WorldWideScience

Sample records for astatine 194

  1. Bibliography of astatine chemistry and biomedical applications

    International Nuclear Information System (INIS)

    An overall bibliography is presented on astatine chemistry and on the biomedical applications of its 211At isotope. The references were grouped in the following chapters: General reviews; Discovery, Natural Occurence; Nuclear Data; Preparation, Handling, Radiation Risk; Physico-chemical Properties; Astatine Compounds and Chemical Reactions; Biological Effects and Applications. Entries are sorted alphabetically by authors name in each chapter, and cross-references to other chapters are provided if appropriate. (R.P.)

  2. Astatine-211: production and availability.

    Science.gov (United States)

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production. PMID:22201707

  3. Adsorption interaction of astatine species with quartz and gold surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Serov, A. [Paul Scherrer Institute, Villigen (Switzerland). Lab. for Radiochemistry and Environmental Chemistry; Bern Univ. (Switzerland). Dept. for Chemistry and Biochemistry; Aksenov, N.; Bozhikov, G. [Joint Institute for Nuclear Research, Dubna (RU). Flerov Lab. of Nuclear Reactions] (and others)

    2011-07-01

    The adsorption interaction of various astatine species with quartz and gold surfaces was investigated by gas chromatography methods. Due to variations of the redox potential of the carrier gas elemental astatine, astatine oxide and hypo-astatic acid have been produced. The identification of the astatine compounds is based on the analogy assumption to the gas phase chemistry of the closest homologues in group 17 of the periodic table, iodine and bromine. The deposition temperatures as well as enthalpies of adsorption have been determined for the astatine species. The enhancement of the metallic character within group 17 towards higher Z is clearly confirmed. Macroscopic properties (sublimation enthalpy) of previously unstudied AtO{sub 2} and HAtO were estimated. The determined data for elemental astatine were compared to available literature data. Based on the obtained experimental results possible designs of experiments for studying of chemical properties of the recently discovered element 117 can be suggested. (orig.)

  4. Recent advances in the organic chemistry of astatine

    International Nuclear Information System (INIS)

    Investigation on the chemical behaviour of astatine in the last decade are surveyed. The survey covers the physical and chemical properties of astatine, synthesis and identification of organic astatine compounds, their physicochemical properties. A special chapter is devoted to biomedical applications, including inorganic 211At species, 211At-labelled proteins and drugs. An extensive bibliography of the related literature is given. (N.T.) 129 refs.; 12 figs.; 14 tabs

  5. Discovery of the astatine, radon, francium, and radium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, thirty-nine astatine, thirty-nine radon, thirty-five francium, and thirty-four radium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  6. Extraction of astatine isotopes for development of radiopharmaceuticals using a 211Rn-211At generator

    International Nuclear Information System (INIS)

    In order to utilize a 211At isotope, a promising α-emitter for radionuclide therapy, the chemical properties of astatine isotopes are studied. We have examined wet chemistry methods through the distribution ratios of astatine in liquid-liquid extraction. The astatine isotopes have been found to be well extracted into DIPE and MIBK. We observed that the distribution ratio of astatine isotopes increases with concentrations of HCl greater than 3 M, while it decreases with the HCl concentration less than 2 M. The results will be useful for development of the 211Rn-211At generator. (author)

  7. Astatine-211-Labeled Targeted Radiotherapeutics: An Update

    International Nuclear Information System (INIS)

    The heavy halogen 211At was first proposed for use in α-particle targeted radiotherapy more than 30 years ago and continues to be one of the most promising radionuclides for this purpose. Although its 7.2-h half life is not ideal for intravenously administered whole antibodies, it is compatible with the pharmacokinetics of antibody fragments, peptides, aptamers and organic molecules. Its diverse chemistry allows its incorporation into a wide array of targeting vehicles, relying on its chemical similarity to iodine to provide a useful point of departure. On the other hand, the relatively low carbon-astatine bond strength is challenging. In common with the other α-emitters being discussed at this symposium, lack of reliable availability is one of the biggest hurdles in the use of 211At for targeted radiotherapy. However, in the case of 211At, it is not a question of production cost or availability of target material, because 211At can be produced in reasonable yield from natural bismuth targets. Rather, the difficulty is the lack of cyclotrons equipped with the medium energy α-particle beams required for its production. If the infrastructure for producing 211At is to be improved to the stage where 211At-labeled radiopharmaceuticals can have a meaningful impact, several developments must occur. First, the ability to produce clinically relevant levels of 211At that can be shipped to remote locations in chemically tractable form must be demonstrated. Approaches under consideration include compensating for radiolysis-mediated effects and the consideration of alternative chemistries. Second, strategies for compensating for heterogeneities in dose deposition must be developed, hopefully in a way that is compatible with approval for human use. And third, it is essential that more clinical trials be performed with 211At-labeled therapeutics, particularly in settings of minimum residual disease where the radiobiological advantages of α-particles can be best exploited. Our

  8. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    CERN Document Server

    Rothe, S; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yu; Köster, U; Lane, J; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of smallest quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.317510(8) eV. New ab initio calculations were performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of super-heavy element 117, the heaviest homologue of astatine.

  9. Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates.

    Science.gov (United States)

    Aneheim, Emma; Gustafsson, Anna; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Svedhem, Sofia; Lindegren, Sture

    2016-03-16

    Effective treatment of metastasis is a great challenge in the treatment of different types of cancers. Targeted alpha therapy utilizes the short tissue range (50-100 μm) of α particles, making the method suitable for treatment of disseminated occult cancers in the form of microtumors or even single cancer cells. A promising radioactive nuclide for this type of therapy is astatine-211. Astatine-211 attached to tumor-specific antibodies as carrier molecules is a system currently under investigation for use in targeted alpha therapy. In the common radiolabeling procedure, astatine is coupled to the antibody arbitrarily on lysine residues. By instead coupling astatine to disulfide bridges in the antibody structure, the immunoreactivity of the antibody conjugates could possibly be increased. Here, the disulfide-based conjugation was performed using a new coupling reagent, maleimidoethyl 3-(trimethylstannyl)benzamide (MSB), and evaluated for chemical stability in vitro. The immunoconjugates were subsequently astatinated, resulting in both high radiochemical yield and high specific activity. The MSB-conjugate was shown to be stable with a long shelf life prior to the astatination. In a comparison of the in vivo distribution of the new immunoconjugate with other tin-based immunoconjugates in tumor-bearing mice, the MSB conjugation method was found to be a viable option for successful astatine labeling of different monoclonal antibodies. PMID:26791409

  10. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    OpenAIRE

    Rothe, S.; A. N. Andreyev; Antalic, S; Borschevsky, A.; Capponi, L.; Cocolios, T.E.; Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the io...

  11. The {sup 194}Os/{sup 194}Ir generator: Production and purification of {sup 194}Os

    Energy Technology Data Exchange (ETDEWEB)

    Mirzadeh, S.; Rice, D.E.; Callahan, A.P.; Knapp, F.F. Jr.

    1992-02-01

    Iridium-194 (t{sub {1/2}} = 19.15 h) decays by {beta}-particle emission (E{sub {beta}}{sup max} = 2.236 MeV) and is a potential candidate for radioimmunotherapy [1,2]. An important characteristic is availability of carrier-free {sup 194}Ir from {beta}-decay of {sup 194}Os (t{sub {1/2}} = 6 y). The {sup 194}Os parent nuclei is produced in a fission nuclear reactor with double neutron capture on {sup 192}Os (41.0% natural abundance). We report here the preliminary nuclear data for production of {sup 194}OS and discuss the feasibility of producing sufficient quantities of {sup 194}Os required for the fabrication of the large-scale generators for further studies. In addition, we describe a novel gas- thermochromatographic method (GTC) for the one step conversion of metallic Os to OsO{sub 4} and subsequent separation and purification of OsO{sub 4}. 6 refs., 1 fig., 1 tab.

  12. The sup 194 Os/ sup 194 Ir generator: Production and purification of sup 194 Os

    Energy Technology Data Exchange (ETDEWEB)

    Mirzadeh, S.; Rice, D.E.; Callahan, A.P.; Knapp, F.F. Jr.

    1992-01-01

    Iridium-194 (t{sub {1/2}} = 19.15 h) decays by {beta}-particle emission (E{sub {beta}}{sup max} = 2.236 MeV) and is a potential candidate for radioimmunotherapy (1,2). An important characteristic is availability of carrier-free {sup 194}Ir from {beta}-decay of {sup 194}Os (t{sub {1/2}} = 6 y). The {sup 194}Os parent nuclei is produced in a fission nuclear reactor with double neutron capture on {sup 192}Os (41.0% natural abundance). We report here the preliminary nuclear data for production of {sup 194}OS and discuss the feasibility of producing sufficient quantities of {sup 194}Os required for the fabrication of the large-scale generators for further studies. In addition, we describe a novel gas- thermochromatographic method (GTC) for the one step conversion of metallic Os to OsO{sub 4} and subsequent separation and purification of OsO{sub 4}. 6 refs., 1 fig., 1 tab.

  13. 49 CFR 194.115 - Response resources.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Response resources. 194.115 Section 194.115... Response Plans § 194.115 Response resources. (a) Each operator shall identify and ensure, by contract or other approved means, the resources necessary to remove, to the maximum extent practicable, a worst...

  14. 42 CFR 460.194 - Corrective action.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Corrective action. 460.194 Section 460.194 Public...) Federal/State Monitoring § 460.194 Corrective action. (a) A PACE organization must take action to correct... corrective actions. (c) Failure to correct deficiencies may result in sanctions or termination, as...

  15. 21 CFR 155.194 - Catsup.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Catsup. 155.194 Section 155.194 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CANNED VEGETABLES Requirements for Specific Standardized Canned Vegetables § 155.194 Catsup....

  16. 40 CFR 194.27 - Peer review.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Peer review. 194.27 Section 194.27... CFR PART 191 DISPOSAL REGULATIONS Compliance Certification and Re-certification General Requirements § 194.27 Peer review. (a) Any compliance application shall include documentation of peer review that...

  17. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    DEFF Research Database (Denmark)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom;

    2015-01-01

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical...... and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting...... vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method...

  18. Study of Astatine (III) reactions with O, S and N ligands in solution

    International Nuclear Information System (INIS)

    Full text of publication follows. Astatine (At, Z=85: [Xe]4f145d106s26p5) belongs to the halogen group and is located below iodine in the periodic table. One of its isotopes (211At) appears promising as a therapeutic agent in nuclear medicine (Ref.1) owing to the energy of the alpha particles emitted during the disintegration of its nucleus and its short physical half-life (7.2 h). Since there are no stable isotopes of astatine, the chemistry of this element remains poorly understood. Generally, At is supposed to behave as a halogen (Ref.2) but it has been shown recently in our group that astatine presents a metallic behaviour in aqueous solution: it notably exists as At+ and AtO+ species under the oxidation states +I and +III (Ref.3). At the present time, the number of studies dealing with the complexation properties of the cationic forms of astatine remains limited (Ref.4), owing to its low availability. In this work, we have investigated the reactions of AtO+ species with different hetero-atomic (N, S, O) model ligands. A combined approach based on experimental and theoretical studies has been used (Ref.5). On account of the difficulties of experimental investigations of astatine species, the reactivity of AtO+ was explored using a competition method founded on astatine distributions between two distinct phases. Furthermore, for each AtO+/ ligand complex, the nature of the species formed and the associated thermodynamic constants were determined by computational modeling (DFT calculations). In this framework, an original computational methodology was developed to take into account the specificities of astatine, notably the associated relativistic effects. The computed equilibrium constants have been confronted with the experimental results. This comparison demonstrates an outstanding coherence between experience and theory. Furthermore, the analysis of the results shows a key role of solvent effects on astatine chemistry. Lastly, a specific reactivity for the

  19. Some aspects of the organic, biological and inorganic chemistry of astatine

    International Nuclear Information System (INIS)

    Astatine has no stable isotopes and the radioactive isotopes with half-lives sufficiently long for chemical experiments (209At, 210At, 211At) must be produced artificially with a cyclotron or with a high energy accelerator by spallation of Th. This thesis deals with the synthesis and chemistry of At-compounds and the determination of some of their properties. (C.F.)

  20. Dicty_cDB: SLA194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLA194 (Link to dictyBase) - - - Contig-U16368-1 SLA194Z (Link... to Original site) - - SLA194Z 528 - - - - Show SLA194 Library SL (Link to library) Clone ID SLA194 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLA1-D/SLA194Q.Seq.d/ Representative seq. ID SLA19...4Z (Link to Original site) Representative DNA sequence >SLA194 (SLA194Q) /CSM/SL/SLA1-D/SLA194Q.Seq.d/ XXXXX...CAAGCTCAGAAAGCTCAGAAAGCTCATCAGCCACTTCATAAATAAAACTTTGATC sequence update 1997. 5.16 Translated Amino Acid seq

  1. 46 CFR 194.15-5 - Ventilation.

    Science.gov (United States)

    2010-10-01

    ... CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Chemistry Laboratory and Scientific Laboratory § 194... minutes based upon the volume of the compartment. (1) Power ventilation units shall have...

  2. Astatine-211 Pathway from Radiochemistry to Clinical Investigation

    International Nuclear Information System (INIS)

    Particularly in clinical settings where tumour burden is low and cancers are located in close proximity to essential normal tissue structures, α-particle emitting radionuclides can offer significant advantages for targeted radionuclide therapy. One of the first alpha emitters to be evaluated for this purpose is the 7.2-h half-life radiohalogen Astatine-211 (211At). From a commercialization-potential perspective 211At, is less appealing than the longer half-life alpha particle emitters Radium-223, Actinium-225 and Thorium-227, which have become the focus of many laboratories. However, if methods for providing a better supply of 211At could be developed, this alpha emitter would be the radionuclide of choice for many potential therapeutic applications. With regard to the production of 211At, this can be readily be accomplished by bombarding natural bismuth targets with 28−29.5 MeV alpha particles via the 209Bi(α,2n)211At reaction. The goal is to utilize an alpha particle beam energy that provides the required balance for maximizing 211At production while minimizing creation of 210At, which is problematic because of its 138.4-day half life alpha-particle emitting daughter, 210Po. For most intended clinical applications, alpha particle beam energy of about 29 MeV offers the best compromise between maximizing yield and providing 211At with sufficient radionuclidic purity for clinical use. Clinically relevant levels of 211At have been produced at several institutions using both internal and external cyclotron targets

  3. 46 CFR 194.10-25 - Ventilation.

    Science.gov (United States)

    2010-10-01

    ... magazines. (1) All integral magazines shall be provided with natural or mechanical ventilation. Design... temperature below 100 °F. with 88 °F. weather air. Mechanical cooling may be used where ventilation... 46 Shipping 7 2010-10-01 2010-10-01 false Ventilation. 194.10-25 Section 194.10-25 Shipping...

  4. 49 CFR 194.117 - Training.

    Science.gov (United States)

    2010-10-01

    ... for emergency response operations in 29 CFR 1910.120, including volunteers or casual laborers employed during a response who are subject to those standards pursuant to 40 CFR part 311. ... 49 Transportation 3 2010-10-01 2010-10-01 false Training. 194.117 Section 194.117...

  5. 40 CFR 194.22 - Quality assurance.

    Science.gov (United States)

    2010-07-01

    ... COMPLIANCE WITH THE 40 CFR PART 191 DISPOSAL REGULATIONS Compliance Certification and Re-certification General Requirements § 194.22 Quality assurance. (a)(1) As soon as practicable after April 9, 1996, the... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Quality assurance. 194.22 Section...

  6. 46 CFR 194.15-19 - Electrical.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Electrical. 194.15-19 Section 194.15-19 Shipping COAST....15-19 Electrical. (a) All electrical equipment located within 18 inches of the deck of the chemical laboratory shall be in accordance with the applicable requirements of Subchapter J (Electrical...

  7. Dicty_cDB: AFM194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFM194 (Link to dictyBase) - - - - AFM194P (Link to Original site) AFM194F 623 AFM...194Z 703 AFM194P 1306 - - Show AFM194 Library AF (Link to library) Clone ID AFM194 (Link... to dictyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig - Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/AF/AFM...1-D/AFM194Q.Seq.d/ Representative seq. ID AFM194P (Link to... Original site) Representative DNA sequence >AFM194 (AFM194Q) /CSM/AF/AFM1-D/AFM194Q.Seq.d/ ATTTTATAATCACTGT

  8. An attempt to explore the production routes of Astatine radionuclides: Theoretical approach

    OpenAIRE

    Maiti, Moumita; Lahiri, Susanta

    2008-01-01

    In order to fulfil the recent thrust of Astatine radionuclides in the field of nuclear medicine various production routes have been explored in the present work. The possible production routes of $^{209-211}$At comprise both light and heavy ion induced reactions at the bombarding energy range starting from threshold to maximum 100 MeV energy. For this purpose, we have used the nuclear reaction model codes TALYS, ALICE91 and PACE-II. Excitation functions of those radionuclides, produced throug...

  9. Dicty_cDB: CHS194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHS194 (Link to dictyBase) - - - Contig-U11696-1 - (Link to Original site) CHS1...94F 159 - - - - - - Show CHS194 Library CH (Link to library) Clone ID CHS194 (Link to dicty...iol.tsukuba.ac.jp/CSM/CH/CHS1-D/CHS194Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >CHS194 (CHS194Q) /CSM/CH/CHS1-D/CHS194Q.Seq.d/ ATAATTATAAAAATTAC...omology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value CHS194 (CHS194Q) /CSM/CH/CHS1-D/CHS1

  10. Dicty_cDB: CHR194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR194 (Link to dictyBase) - - - Contig-U16433-1 CHR194P (Link to Original site) CHR...194F 144 CHR194Z 570 CHR194P 694 - - Show CHR194 Library CH (Link to library) Clone ID CHR... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHR1-D/CHR194Q.Seq.d/ Representative seq. ID CHR...194P (Link to Original site) Representative DNA sequence >CHR194 (CHR194Q) /CSM/CH/CHR1-D/CHR1...A sequence from clone RP11-475L16 on chromosome 10. 48 0.25 1 CR940353 |CR940353.

  11. Linear clusters of galaxies - A194

    Science.gov (United States)

    Chapman, G. N. F.; Geller, M. J.; Huchra, J. P.

    1988-01-01

    New measurements for 160 redshifts and previous measurements for 108 other redshifts are presented for galaxies within 5 deg of A194. The galaxy distribution in A194 is shown to be inconsistent with a spherically symmetric King model. A mass-to-light ratio is derived using the virial theorem which is lower than the mean for the groups in the CfA redshift survey (Huchra and Geller, 1982; Geller, 1984). A nonparametric test for galaxy-cluster alignment and a Chi-squared test are used to search for alignment of galaxy major axes with the axis of A194. Evidence for neither luminosity segregation nor significant differences in the velocity or surface distributions of galaxies as a function of morphological type is found.

  12. Determination of the electron affinity of astatine and polonium by laser photodetachment

    CERN Multimedia

    We propose to conduct the first electron anity (EA) measurements of the two elements astatine (At) and polonium (Po). Collinear photodetachment spectroscopy will allow us to measure these quantities with an uncertainty limited only by the spectral linewidth of the laser. We plan to use negative ion beams of the two radioactive elements At and Po, which are only accessible on-line and at ISOLDE. The feasibility of our proposed method and the functionality of the experimental setup have been demonstrated at ISOLDE in o-line tests by the clear observation of the photodetachment threshold for stable iodine. This proposal is based on our Letter of Intent I-148 [1].

  13. 34 CFR 300.194 - Show cause hearing.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Show cause hearing. 300.194 Section 300.194 Education... DISABILITIES State Eligibility By-Pass for Children in Private Schools § 300.194 Show cause hearing. (a) If a show cause hearing is requested, the Secretary— (1) Notifies the SEA and affected LEA or other...

  14. 49 CFR Appendix B to Part 194 - High Volume Areas

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false High Volume Areas B Appendix B to Part 194... Pt. 194, App. B Appendix B to Part 194—High Volume Areas As of January 5, 1993 the following areas are high volume areas: Major rivers Nearest town and state Arkansas River N. Little Rock, AR....

  15. 46 CFR 194.15-11 - Flushing systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Flushing systems. 194.15-11 Section 194.15-11 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Chemistry Laboratory and Scientific Laboratory § 194.15-11 Flushing systems. (a)...

  16. 46 CFR 194.05-3 - Chemical stores.

    Science.gov (United States)

    2010-10-01

    ... shall be classed, marked and labeled in accordance with 49 CFR part 172: (1) Explosives. (2) Flammable... under paragraph (a) of this section but not specifically listed by name in 49 CFR 172.101 must be... 46 Shipping 7 2010-10-01 2010-10-01 false Chemical stores. 194.05-3 Section 194.05-3...

  17. 28 CFR 19.4 - Cost and percentage estimates.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Cost and percentage estimates. 19.4... RECOVERY OF MISSING CHILDREN § 19.4 Cost and percentage estimates. It is estimated that this program will cost DOJ $78,000 during the initial year. This figure is based on estimates of printing, inserting,...

  18. 49 CFR 194.101 - Operators required to submit plans.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Operators required to submit plans. 194.101... PLANS FOR ONSHORE OIL PIPELINES Response Plans § 194.101 Operators required to submit plans. (a) Except... Coordinator (FOSC) to require an operator of a pipeline in paragraph (b) to submit a response plan,...

  19. 13 CFR 120.194 - Use of computer forms.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by...

  20. 46 CFR 194.20-19 - Piping and electrical requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Piping and electrical requirements. 194.20-19 Section... Storerooms § 194.20-19 Piping and electrical requirements. (a) Piping, electrical equipment, and wiring shall... storeroom itself. (b) The electrical installation shall be in accordance with the applicable requirements...

  1. 46 CFR 194.20-11 - Flushing systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Flushing systems. 194.20-11 Section 194.20-11 Shipping... Flushing systems. (a) Provision shall be made for flushing away chemical spills. (b) If a drainage system is installed, it shall be separate from any other drainage system....

  2. 26 CFR 1.194-1 - Amortization of reforestation expenditures.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Amortization of reforestation expenditures. 1....194-1 Amortization of reforestation expenditures. (a) In general. Section 194 allows a taxpayer to elect to amortize over an 84-month period, up to $10,000 of reforestation expenditures (as defined...

  3. Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

    Science.gov (United States)

    Guérard, François; Lee, Yong-Sok; Baidoo, Kwamena; Gestin, Jean-François; Brechbiel, Martin W

    2016-08-22

    Aryliodonium salts have become precursors of choice for the synthesis of (18) F-labeled tracers for nuclear imaging. However, little is known on the reactivity of these compounds with heavy halides, that is, radioiodide and astatide, at the radiotracer scale. In the first comparative study of radiohalogenation of aryliodonium salts with (125) I(-) and (211) At(-) , initial experiments on a model compound highlight the higher reactivity of astatide compared to iodide, which could not be anticipated from the trends previously observed within the halogen series. Kinetic studies indicate a significant difference in activation energy (Ea =23.5 and 17.1 kcal mol(-1) with (125) I(-) and (211) At(-) , respectively). Quantum chemical calculations suggest that astatination occurs via the monomeric form of an iodonium complex whereas iodination occurs via a heterodimeric iodonium intermediate. The good to excellent regioselectivity of halogenation and high yields achieved with diversely substituted aryliodonium salts indicate that this class of compounds is a promising alternative to the stannane chemistry currently used for heavy radiohalogen labeling of tracers in nuclear medicine. PMID:27305065

  4. Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

    CERN Document Server

    Andreyev, Andrei

    2013-01-01

    Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

  5. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    Energy Technology Data Exchange (ETDEWEB)

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  6. 41 CFR 102-194.35 - Should I create electronic Standard or Optional forms?

    Science.gov (United States)

    2010-07-01

    ... electronic Standard or Optional forms? 102-194.35 Section 102-194.35 Public Contracts and Property Management... PROGRAMS 194-STANDARD AND OPTIONAL FORMS MANAGEMENT PROGRAM § 102-194.35 Should I create electronic Standard or Optional forms? Yes, you should create electronic Standard or Optional forms, especially...

  7. Studies of {sup 194,195,197}Po

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, M.P.; Ahmad, I.; Crowell, B. [and others

    1995-08-01

    The energy systematics of low-lying polonium states show sudden changes near N = 114. The observed drops in the low-lying levels of {sup 196,198}Po relative to the heavier isotopes indicate significant changes in the underlying structure of these nuclei. It is thought that this change is due to the onset of vibrational collectivity brought about by the quadrupole interaction between neutron and proton-pairs. In order to extend the Po systematics even further, we measured, for the first time, states in {sup 194,195,197}Po using the {sup 28}Si + {sup 170}Yb reaction at a beam energy of 142 MeV. The beam was supplied by ATLAS, and the data were taken with 10 Compton-suppressed Ge detectors placed at the target position of the Fragment Mass Analyzer. Preliminary level schemes were constructed for {sup 194,195,197}Po based on {gamma}-{gamma} and {gamma}-FMA coincidences. The results for {sup 194}Po show that the 2{sup +} - 0{sup +} transition energy decreased in energy by 140 keV relative to {sup 196}Po suggesting that this nucleus moved beyond the vibrational limit to more collective motion. An extrapolation of the systematics predicts that the 2{sup +} energy could drop another 140 keV between {sup 194}Po and {sup 192}Po which would indicate the onset of rotational motion. Currently, we have an approved experiment to investigate the decay of yrast isomers in {sup 194}Po which will allow us to (1) confirm our earlier level scheme of {sup 194}Po, and (2) assess the experimental conditions needed for a future study of {sup 192}Po.

  8. Identical Bands and Alignment in 193,194Tl

    Institute of Scientific and Technical Information of China (English)

    HE Xiao-Tao; YU Shao-Ying; LIU Shu-Xin; LIU Yan-Xin; ZHAO En-Guang

    2004-01-01

    @@ The microscopic mechanism of the identical bands in odd odd nucleus 194Tl and its neighbour odd-A nucleus 193Tl are investigated using the particle-number conserving method with monopole and quadrupole pairing interaction.It is found that the blocking effect plays an important role in the variation of moments of inertia (J(1) and J(2))with rotational frequency for the superdeformed bands and identical bands. The alignment of 194Tl bands with respect to the 193 Tl(1) band used as a reference is also discussed.

  9. High spin band structures in doubly-odd $^{194}$Tl

    CERN Document Server

    Pai, H; Bhattacharyya, S; Gohil, M R; Bhattacharjee, T; Bhattacharya, C; Palit, R; Saha, S; Sethi, J; Trivedi, T; Thakur, Shital; Naidu, B S; Jadav, S K; Donthi, R; Goswami, A; Chanda, S

    2012-01-01

    The high-spin states in odd-odd $^{194}$Tl nucleus have been studied by populating them using the $^{185,187}$Re($^{13}$C, xn) reactions at 75 MeV of beam energy. $\\gamma-\\gamma$ coincidence measurement has been performed using the INGA array with a digital data acquisition system to record the time stamped data. Definite spin-parity assignment of the levels was made from the DCO ratio and the IPDCO ratio measurements. The level scheme of $^{194}$Tl has been extended up to 4.1 MeV in excitation energy including 19 new gamma ray transitions. The $\\pi h_{9/2} \\otimes \

  10. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, Sebastian

    2012-09-24

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  11. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    International Nuclear Information System (INIS)

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  12. 40 CFR 194.51 - Consideration of protected individual.

    Science.gov (United States)

    2010-07-01

    ... COMPLIANCE WITH THE 40 CFR PART 191 DISPOSAL REGULATIONS Compliance Certification and Re-certification Individual and Ground-Water Protection Requirements § 194.51 Consideration of protected individual... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Consideration of protected...

  13. 27 CFR 41.194 - Articles of partnership or association.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or... AND TUBES, AND PROCESSED TOBACCO Tobacco Products Importers § 41.194 Articles of partnership or..., must furnish with its application for permit required by § 41.191 a true copy of the articles...

  14. 46 CFR 194.10-10 - Integral magazine construction.

    Science.gov (United States)

    2010-10-01

    ... HANDLING, USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-10 Integral... spaces suitable approved incombustible thermal insulation shall be provided to prevent condensation of... not be installed within or pass through the magazine. Electrical cables enclosed in a watertight...

  15. 40 CFR 194.46 - Removal of waste.

    Science.gov (United States)

    2010-07-01

    ... PROGRAMS CRITERIA FOR THE CERTIFICATION AND RE-CERTIFICATION OF THE WASTE ISOLATION PILOT PLANT'S COMPLIANCE WITH THE 40 CFR PART 191 DISPOSAL REGULATIONS Compliance Certification and Re-certification... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Removal of waste. 194.46 Section...

  16. Radiobiological Effects of Alpha-Particles from Astatine-211: From DNA Damage to Cell Death

    Energy Technology Data Exchange (ETDEWEB)

    Claesson, Kristina

    2011-05-15

    In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an alpha-particle emitting radionuclide, promising for targeted radioimmunotherapy of isolated tumor cells and microscopic clusters. To improve development of safe radiotherapy using 211At it is important to increase our knowledge of the radiobiological effects in cells. During radiotherapy, both tumors and adjacent normal tissue will be irradiated and therefore, it is of importance to understand differences in the radio response between proliferating and resting cells. The aim of this thesis was to investigate effects in fibroblasts with different proliferation status after irradiation with alpha-particles from 211At or X-rays, from inflicted DNA damage, to cellular responses and biological consequences. Throughout this work, irradiation was performed with alpha-particles from 211A or X-rays. The induction and repair of double-strand breaks (DSBs) in human normal fibroblasts were investigated using pulsed-field gel electrophoresis and fragment analysis. The relative biological effectiveness (RBE) of 211At for DSB induction varied between 1.4 and 3.1. A small increase of DSBs was observed in cycling cells compared to stationary cells. The repair kinetics was slower after 211At and more residual damage was found after 24 h. Comparison between cells with different proliferation status showed that the repair was inefficient in cycling cells with more residual damage, regardless of radiation quality. Activation of cell cycle arrests was investigated using immunofluorescent labeling of the checkpoint kinase Chk2 and by measuring cell cycle distributions with flow cytometry analysis. After alpha-particle irradiation, the average number of Chk2-foci was larger and the cells had a more affected cell cycle progression for several weeks compared with X-irradiated cells, indicating a more powerful arrest after 211At

  17. 26 CFR 1.194-4 - Time and manner of making election.

    Science.gov (United States)

    2010-04-01

    ... section, an election to amortize reforestation expenditures under section 194 shall be made by entering... for which reforestation expenditures are being amortized under section 194. The election may only be... election to amortize reforestation expenditures under section 194 may be made by a statement on,...

  18. Decay from the superdeformed bands in {sup 194}Hg

    Energy Technology Data Exchange (ETDEWEB)

    Henry, R.G.; Khoo, T.L.; Carpenter, M.P. [and others

    1995-08-01

    Superdeformed bands in {sup 194}H g were studied using the early implementation of Gammasphere. The response functions for the Ge detectors were measured for the first time as part of this experiment. Experiments were performed with both a backed target (where the residue stopped in the Au backing) and a thin target (where the residue recoiled into vacuum). This will permit measurements of the decay times of the quasicontinuum {gamma}rays. The spectrum in coincidence with the yrast SD band in {sup 194}Hg reveals the same features as found in the quasicontinuum structure in {sup 192}Hg. These features include: statistical {gamma}rays feeding the SD band, a pronounced E2 peak from transitions feeding the SD band, a Ml/E2 bump at low energies that is associated with the last stages of feeding of the superdeformed band, and a quasicontinuous distribution from {gamma}rays linking SD and normal states, including a sizable clustering of strength around 1.7 MeV. The remarkable similarity of the spectra coincident with SD bands in {sup 192,194}Hg provides additional support for a statistical process for decay out of the SD states. This similarity contrasts with differences observed in the spectrum coincident with the SD band in the odd-even {sup 191}Hg, confirming the predictions about the role of pairing (in normal states) in influencing the shape of the decay-out spectrum.

  19. MicroRNA-194 promotes osteoblast differentiation via downregulating STAT1

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jun [Department of Emergency, Shannxi Province People' s Hospital, Third Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710052 (China); He, Xijing [Department of Orthopaedics, Second Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710004 (China); Wei, Wenzhi [Department of Emergency, Shannxi Province People' s Hospital, Third Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710052 (China); Zhou, Xiaobo, E-mail: xiaobozhouxa@163.com [Department of Immunology and Pathogenic Biology, Medical School, Xi' an Jiaotong University, Xi' an 710061 (China)

    2015-05-01

    Osteoblast differentiation is a vital process in maintaining bone homeostasis in which various transcriptional factors, signaling molecules, and microRNAs (miRNAs) are involved. Recently, signal transducer and activator of transcription 1 (STAT1) has been found to play an important role in regulating osteoblast differentiation. Here, we identified that STAT1 expression was regulated by miR-194. Using mouse bone mesenchymal stem cells (BMSCs), we found that miR-194 expression was significantly increased following osteoblast differentiation induction. Overexpression of miR-194 by lentivirus-mediated gene transfer markedly increased osteoblast differentiation, whereas inhibition of miR-194 significantly suppressed osteoblast differentiation of BMSCs. Using a dual-luciferase reporter assay, a direct interaction between miR-194 and the 3′-untranslated region (UTR) of STAT1 was confirmed. Additionally, miR-194 regulated mRNA and protein expression of STAT1 in BMSCs. Further analysis showed that miR-194 overexpression promoted the nuclear translocation of runt-related transcription factor 2 (Runx2), which is critical for osteoblast differentiation. In contrast, inhibition of miR-194 blocked the nuclear translocation of Runx2. Moreover, overexpression of STAT1 significantly blocked Runx2 nuclear translocation and osteoblast differentiation mediated by miR-194 overexpression. Taken together, our data suggest that miR-194 regulates osteoblast differentiation through modulating STAT1-mediated Runx2 nuclear translocation. - Highlights: • Overexpression of miR-194 significantly increased osteoblast differentiation. • miR-194 directly targeted the 3′- UTR of STAT1. • miR-194 regulated the expression of STAT1. • Overexpression of miR-194 promoted the nuclear translocation of Runx2.

  20. Dicty_cDB: SLE194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available E Sequences producing significant alignments: (bits) Value N ( AU034692 ) Dictyostelium discoideum slug cDNA..., clone SLE194. 268 2e-91 2 ( AU033787 ) Dictyostelium discoideum slug cDNA, clon...e SLB438. 260 1e-86 2 ( AU040025 ) Dictyostelium discoideum slug cDNA, clone SLH472. 260 1e-86 2 ( AU033785 ...) Dictyostelium discoideum slug cDNA, clone SLB436. 260 1e-86 2 ( AU033617 ) Dictyostelium discoideum slug c...DNA, clone SLB234. 260 1e-86 2 ( AU039989 ) Dictyostelium discoideum slug cDNA, clone SLH386. 260 1e-86 2 (

  1. DSAM lifetime measurements for the chiral pair in 194Tl

    International Nuclear Information System (INIS)

    Most important for the identification of chiral symmetry in atomic nuclei is to establish a pair of bands that are near-degenerate in energy, but also in B(M1) and B(E2) transition probabilities. Dedicated lifetime measurements were performed for four bands of 194Tl, including the pair of four-quasiparticle chiral bands with close near-degeneracy, considered as a prime candidate for best chiral symmetry pair. The lifetime measurements confirm the excellent near-degeneracy in this pair and indicate that a third band may be involved in the chiral symmetry scenario. (orig.)

  2. Production of tungsten-188 and osmium-194 in a nuclear reactor for new clinical generators

    Energy Technology Data Exchange (ETDEWEB)

    Mirzadeh, S.; Knapp, F.F. Jr.; Callahan, A.P.

    1991-01-01

    Rhenium-188 and iridium-194 are potential candidates for radioimmunotherapy with monoclonal antibodies directed against tumor-associated antigens. Both nuclei are short-lived and decay by high energy {Beta}{minus} emission. In addition, both nuclei emit {gamma}-rays with energy suitable for imaging. An important characteristics is availability of {sup 188}Re and {sup 194}Ir from decay of reactor-produced parents ({sup 188}W and {sup 194}Os, respectively) in convenient generator systems. The {sup 188}W and {sup 194}Os are produced by double neutron capture of {sup 186}W and {sup 192}Os, respectively. The large scale production yields of {sup 188}W in several nuclear reactors will be presented. We also report a new management for the cross-section of {sup 193}Os(n,{gamma}){sup 194}Os reaction and discuss the feasibility of producing sufficient quantities of {sup 194}Os. 17 refs., 1 fig., 2 tabs.

  3. Production of tungsten-188 and osmium-194 in a nuclear reactor for new clinical generators

    International Nuclear Information System (INIS)

    Rhenium-188 and iridium-194 are potential candidates for radioimmunotherapy with monoclonal antibodies directed against tumor-associated antigens. Both nuclei are short-lived and decay by high energy β- emission. In addition, both nuclei emit γ-rays with energy suitable for imaging. An important characteristic is availability of 188Re and 194Ir from decay of reactor-produced parents (188W and 194Os, respectively) in covenient generator systems. The 188W and 194Os are produced by double neutron capture of 186W and 192Os, respectively. The large scale production yields of 188W in several nuclear reactors will be presented. We also report a new measurement for the cross-section of 193Os(n, γ)194Os reaction and discuss the feasibility of producing sufficient quantities of 194Os. (orig.)

  4. Sandwich-like Cu1.94S-ZnS-Cu1.94S nanoheterostructure: structure, formation mechanism and localized surface plasmon resonance behavior

    Science.gov (United States)

    Huang, Feng; Xu, Ju; Chen, Daqin; Wang, Yuansheng

    2012-10-01

    In this communication, a thermolysis route is developed to synthesize novel Cu1.94S-ZnS-Cu1.94S nanoheterostructures with interesting sandwich-like architectures, taking Cu1.94S nanoplates as precursors. Evidently, the trimeric nanostructure is formed by a three-stage process, which includes the Zn-oleate induced assembling of Cu1.94S nanoplate couples, the heteronucleation and growth of a ZnS layer between two Cu1.94S plates dominated by interfacial diffusion, and the catalyst assisted axial growth of ZnS nanorod following the solution-liquid-solid mechanism. With epitaxial growth of ZnS nanocrystal between two Cu1.94S nanoplates, the localized surface plasmon resonance frequency of Cu1.94S shifts from 1875 to 1323 nm, indicating that this new material is potentially applicable as a light absorbing agent in laser photothermal therapy. The reported growth mechanism may provide new strategies for designing and fabricating various technologically important polymeric nanoheterostructures.

  5. MicroRNA-194 is a Marker for Good Prognosis in Clear Cell Renal Cell Carcinoma.

    Science.gov (United States)

    Nofech-Mozes, Roy; Khella, Heba W Z; Scorilas, Andreas; Youssef, Leza; Krylov, Sergey N; Lianidou, Evi; Sidiropoulos, Konstantinos G; Gabril, Manal; Evans, Andrew; Yousef, George M

    2016-04-01

    Clear cell renal cell carcinoma (ccRCC) is the most prevalent adult kidney cancer. Prognostic markers are needed to guide patient management toward aggressive versus more conservative approaches, especially for small tumors ≤4 cm. miR-194 was reported to be downregulated in several cancers and is involved in epithelial to mesenchymal transition. We evaluated miR-194 as a prognostic marker in ccRCC. In a cohort of 234 patients with primary ccRCC, we correlated miR-194 expression level with multiple clinicopathological features including disease-free and overall survival, tumor size, clinical stage, and histological grade. Our results shows a stepwise decrease in miR-194 expression from normal kidney to primary ccRCC (P = 0.0032) and a subsequent decrease from primary to metastatic lesions. Additionally, patients with higher miR-194 expression has significantly longer disease-free survival (P = 0.041) and overall survival (P = 0.031) compared to those with lower expression. In multivariate analysis, miR-194-positive tumors retain significance in disease-free survival and overall survival, suggesting miR-194 is an independent marker for good prognosis in ccRCC. Moreover, miR-194 is a marker for good prognosis for patients with small renal masses (P = 0.014). These findings were validated on an independent data set from The Cancer Genome Atlas. We also compared miR-194 expression between RCC subtypes. ccRCC had the highest levels, whereas chromophobe RCC and oncocytoma had comparable lower levels. Target prediction coupled with pathway analysis show that miR-194 is predicted to target key molecules and pathways involved in RCC progression. miR-194 represents a prognostic biomarker in ccRCC. PMID:26860079

  6. 33 CFR 110.194a - Mobile Bay, Ala., and Mississippi Sound, Miss.

    Science.gov (United States)

    2010-07-01

    ... Sound, Miss. 110.194a Section 110.194a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Mississippi Sound, Miss. (a) The anchorage grounds. (1) The waters of lower Mobile Bay, near Cedar Point... south by latitude 30°20′00″, and on the west by longitude 88°06′00″. (2) The waters of Mississippi...

  7. 34 CFR Appendix B to Part 403 - Examples for 34 CFR 403.194-Comparability Requirements

    Science.gov (United States)

    2010-07-01

    ... TECHNOLOGY EDUCATION PROGRAM Pt. 403, App. B Appendix B to Part 403—Examples for 34 CFR 403.194—Comparability... 34 Education 3 2010-07-01 2010-07-01 false Examples for 34 CFR 403.194-Comparability Requirements B Appendix B to Part 403 Education Regulations of the Offices of the Department of...

  8. 40 CFR 194.53 - Consideration of underground sources of drinking water.

    Science.gov (United States)

    2010-07-01

    ... of drinking water. 194.53 Section 194.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... underground sources of drinking water. In compliance assessments that analyze compliance with part 191, subpart C of this chapter, all underground sources of drinking water in the accessible environment...

  9. 41 CFR 102-194.20 - What is an electronic Standard or Optional form?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is an electronic... 194-STANDARD AND OPTIONAL FORMS MANAGEMENT PROGRAM § 102-194.20 What is an electronic Standard or Optional form? An electronic Standard or Optional form is an officially prescribed set of data residing...

  10. 24 CFR 200.194 - Placement of nonprofit organization on Nonprofit Organization Roster.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Placement of nonprofit organization on Nonprofit Organization Roster. 200.194 Section 200.194 Housing and Urban Development Regulations... Placement and Removal Procedures for Participation in FHA Programs Nonprofit Organization §...

  11. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  12. INTEGRAL Observations of MAXI J1836-194

    DEFF Research Database (Denmark)

    Del Santo, M.; Kuulkers, E.; Rodriguez, J.;

    2011-01-01

    . The source was also clearly detected by JEM-X at 23 sigma level in the 3-10 keV energy band with a flux of about 38 mCrab (~5 ks effective exposure time). The simultaneous IBIS/ISGRI+JEM-X 4-300 keV spectrum can be well described (chi2_red/d.o.f=1.0/18) by a power-law model with photon index 2.......19+/-0.05. There is no evidence of any high-energy cutoff below 200 keV. No disk black-body component (ATEL #3628) is requested by the JEM-X data. The estimated 3-20 keV and 20-100 keV mean fluxes are 1.0E-9 erg/cm2/s and 6.2E-10 erg/cm2/s, respectively. RXTE/PCA spectra (power-law slope as 1.7-1.8) on August 31 (ATEL #3618...... on 2011-09-18 since 03:11:34.0 until 14:48:56.0. MAXI 1836-194 was detected by IBIS/ISGRI at a significance level of 32 sigma and 19 sigma in the 20-40 keV and 40-80 keV bands, respectively (~23 ks effective exposure time). The corresponding fluxes are roughly 48 mCrab and 44 mCrab, respectively...

  13. Properties of superdeformed bands in the A = 194 region

    International Nuclear Information System (INIS)

    At least eighteen superdeformed (SD) bands have been identified in mercury, thallium, and lead nuclei since the report of a SD band in 191Hg. Systematic information is beginning to emerge on the properties of the SD bands in this mass region, and comparisons with SD bands in the A = 150 region are now possible. Recently, data were obtained with the HERA spectrometer at the Lawrence Berkeley Laboratory 88'' Cyclotron on SD bands in 194Pb and 196Pb. In these experiments, we bombarded 176Yb with 24Mg and 26Mg. The cross bombardment was necessary to make the assignment of the band to 196Pb certain. These bands are typical of other SD bands in the region in many ways. The gamma rays have energies that range from about 200 to 800 keV. The gamma-ray spacing decreases from about 40 to 30 keV as the transition energy increases. Their intensities gradually increase as the gamma-ray energies decrease over the upper half of of the sequence, and then sustain a constant value until the one or two lowest energy transitions. 18 refs., 4 figs

  14. The Contribution of Serine 194 Phosphorylation to Steroidogenic Acute Regulatory Protein Function

    OpenAIRE

    Sasaki, Goro; Zubair, Mohamad; Ishii, Tomohiro; Mitsui, Toshikatsu; Hasegawa, Tomonobu; Auchus, Richard J

    2014-01-01

    The steroidogenic acute regulatory protein (StAR) facilitates the delivery of cholesterol to the inner mitochondrial membrane, where the cholesterol side-chain cleavage enzyme catalyzes the initial step of steroid hormone biosynthesis. StAR was initially identified in adrenocortical cells as a phosphoprotein, the expression and phosphorylation of which were stimulated by corticotropin. A number of in vitro studies have implicated cAMP-dependent phosphorylation at serine 194 (S194, S195 in hum...

  15. miR-194 targets RBX1 gene to modulate proliferation and migration of gastric cancer cells.

    Science.gov (United States)

    Chen, Xiaonan; Wang, Yuanyuan; Zang, Wenqiao; Du, Yuwen; Li, Min; Zhao, Guoqiang

    2015-04-01

    RING box protein1 (RBX1), an essential component of SCF E3 ubiquitin ligases, plays an important role in gastric cancer. In the study, miR-194 and RBX1 expression was evaluated in 76 pairs of gastric tumor and non-tumor tissue samples by qRT-PCR, and clinicopathological characteristics were analyzed. CCK8, transwell assay, wound healing assay, and flow cytometry assay were performed to evaluate the effect of miR-194 on gastric cancer (GC) cellular proliferation, invasion, migration, apoptosis, and cell cycle, respectively. Luciferase reporter assays and Western blotting were used to evaluate whether RBX1 is a direct target of miR-194. The Kaplan-Meier method and log-rank test were used to evaluate the correlation between miR-194 or RBX1 expression and patient survival. Then, we found that miR-194 was significantly downregulated and RBX1 upregulated in GC tissues; both of which showed significant association with tumor size, location, invasion, and tumor node metastasis. Cell proliferation, invasion, and migration were significantly restricted with miR-194 overexpression. miR-194 downregulated RBX1 protein expression, and luciferase assays showed that binding sites in the RBX1 3'UTR were required for miR-194-mediated repression of RBX1, indicating that RBX1 was a direct target of miR-194. Transfection of RBX1 without the 3'UTR restored the miR-194-inhibiting migration function. miR-194 overexpression or RBX1 lowexpression was associated with prolonged survival of GC patients. In conclusion, upregulation of miR-194 can inhibit proliferation, migration, and invasion of GC cells, possibly by targeting RBX1. Aberrant expression of miR-194 and RBX1 is correlated to GC patient survival time. PMID:25412959

  16. Removal of Acid Black 194 dye from water by electrocoagulation with aluminum anode.

    Science.gov (United States)

    Vidal, Jorge; Villegas, Loreto; Peralta-Hernández, Juan M; Salazar González, Ricardo

    2016-01-01

    Application of an electrocoagulation process (EC) for the elimination of AB194 textile dye from synthetic and textile wastewater (effluent) contaminated with AB194 dye, was carried out using aluminum anodes at two different initial pH values. Tafel studies in the presence and absence of the dye were performed. The aluminum species formed during the electrolysis were quantified by atomic absorption, and the flocs formed in the process were analyzed by HPLC-MS. Complete removal of AB194 from 1.0 L of solution was achieved applying low densities current at initial pH values of 4.0 and 8.0. The removal of AB194 by EC was possible with a short electrolysis time, removing practically 100% of the total organic carbon content and chemical oxygen demand. The final result was completely discolored water lacking dye and organic matter. An effluent contaminated with 126 mg L(-1) AB194 dye from a Chilean textile industry was also treated by EC under optimized experimental conditions, yielding discolored water and considerably decreasing the presence of organic compounds (dye + dyeing additives), with very low concentrations of dissolved Al(3+). Analysis of flocs showed the presence of the original dye without changes in its chemical structure.

  17. Removal of Acid Black 194 dye from water by electrocoagulation with aluminum anode.

    Science.gov (United States)

    Vidal, Jorge; Villegas, Loreto; Peralta-Hernández, Juan M; Salazar González, Ricardo

    2016-01-01

    Application of an electrocoagulation process (EC) for the elimination of AB194 textile dye from synthetic and textile wastewater (effluent) contaminated with AB194 dye, was carried out using aluminum anodes at two different initial pH values. Tafel studies in the presence and absence of the dye were performed. The aluminum species formed during the electrolysis were quantified by atomic absorption, and the flocs formed in the process were analyzed by HPLC-MS. Complete removal of AB194 from 1.0 L of solution was achieved applying low densities current at initial pH values of 4.0 and 8.0. The removal of AB194 by EC was possible with a short electrolysis time, removing practically 100% of the total organic carbon content and chemical oxygen demand. The final result was completely discolored water lacking dye and organic matter. An effluent contaminated with 126 mg L(-1) AB194 dye from a Chilean textile industry was also treated by EC under optimized experimental conditions, yielding discolored water and considerably decreasing the presence of organic compounds (dye + dyeing additives), with very low concentrations of dissolved Al(3+). Analysis of flocs showed the presence of the original dye without changes in its chemical structure. PMID:26745322

  18. RDDS lifetime measurements of low-lying superdeformed states in {sup 194}Hg

    Energy Technology Data Exchange (ETDEWEB)

    Kuehn, R.; Dewald, A.; Kruecken, R. [Universitaet Koeln (Germany)] [and others

    1996-12-31

    The lifetimes of three low-lying states in the superdeformed (SD) yrast band of {sup 194}Hg were measured by the recoil-distance Doppler-shift method. The deduced transition quadrupole moments, Q{sub t}, equal those extracted from a DSAM measurement for the high-lying states of the band corroborate the assumption that the decay out of SD bands does not strongly affect the structure of the corresponding states. By a simple mixing-model the decay can be described assuming a very small admixture of normal-deformed (ND) states to the decaying SD states. The deduced ND mixing amplitudes for the yrast SD bands in {sup 192,194}Hg and {sup 194}Pb are presented along with average transition quadrupole moments for the lower parts of the excited SD bands.

  19. Clinical Analysis of 194 Cases of Irritable Bowel Syndrome%肠易激综合征194例临床分析

    Institute of Scientific and Technical Information of China (English)

    曲桂霞

    2015-01-01

    Objective To investigate the clinical analysis of irritable bowel syndrome in 194 cases. Methods Selected in our hospital treated 194 cases of patients with irritable bowel syndrome,were randomly divided into observation group and control group,two groups each of 97 patients. The observation group with paroxetine combined oral pinaverium bromide treatment modality for treatment,patients in the control group with oral administration of ammonium treatment modality for treatment of pinaverium bromide. Results The total effective rate of observation group was 78.35%; the control group the total effective rate was 49.48%. The data of the two groups have significant difference(P<0.05). Conclusion Paroxetine combined pinaverium bromide treatment on patients with irritable bowel syndrome has good treatment effect.%目的:探讨对肠易激综合征194例的临床分析。方法选取我院接受治疗的肠易激综合症患者194例,随机分为观察组和对照组,两组各有患者97例。观察组采用口服帕罗西汀联合匹维溴铵的治疗方式进行治疗,对照组患者采用口服匹维溴铵的治疗方式进行治疗。结果观察组总有效率为78.35%;对照组总有效率为49.48%。两组数据具有差异(P<0.05)。结论帕罗西汀联合匹维溴铵的治疗方式对肠易激综症患者有着较好的治疗效果。

  20. To construct the eukaryotic expression plasmid PIRESneo3/miR-194 and establish a miR-194 highly expressed MCF-7 cell%真核表达质粒PIRESneo3/miR-194的构建及其在乳腺癌细胞MCF-7中的表达

    Institute of Scientific and Technical Information of China (English)

    李佳; 王本忠

    2012-01-01

    目的 构建含miR-194基因的真核表达质粒,建立miR-194稳定表达的MCF-7乳腺癌细胞株.方法 设计合成miR-194引物序列,PCR法从乳腺癌231细胞中扩增出目的片段,经双酶切后定向连入PIRESneo3载体,构建PIRESneo3/miR-194真核表达质粒,经酶切、测序检测其构建的正确性.脂质体法将重组质粒转入MCF-7细胞,G418药物筛选出稳定转染的细胞,实时荧光定量PCR法检测稳定转染MCF-7细胞中miR-194基因的表达水平.结果 构建的PIRESneo3/miR-194质粒经酶切、测序等检验表明质粒构建成功,筛选获得稳定高表达miR-194的MCF-7乳腺癌细胞株.结论 成功构建了PIRESneo3/miR-194真核表达质粒以及稳定高表达miR-194的MCF-7细胞株.为进一步观察该基因对乳腺癌细胞的体外效应和以miR-194为靶点的乳腺癌基因治疗研究提供实验基础.%Objective To construct the eukaryotic expression plasmid containing miR-194 genes and establish breast cancer cell lines( MCF-7 ) with stabilized expression of miR-194. Methods MiR-194 primers were designed and miR-194 gene was amplified from cDNA of 231 breast cancer cells by reverse transcription polymerase chain re-action ( PCR ). The miR-194 gene was cloned into PIRESneo3 vector directionally after enzyme cut thus constructing the eukaryotic expression plasmid of PIRESneo3/miR-194. Then the recombinant PIRESneo3/miR-194 plasmid was transfected into the MCF-7 cell line by Lipofectamine, and miR-194 highly expressed cells was selected by G418 ( 600 μg/ml ). The expression level of miR-194 was detected by real-time quantitative PCR. Results The recombinant PIRESneo3/miR-194 plasmid was constructed, and the MCF-7 cell line with highly miR-194 gene was screened. Conclusion miR-194 highly expressed MCF-7 cell line is established sucessfully, which will be a perfect target of miR-194 gene therapy and for observing its function in breast cancer cells.

  1. Yeast Interacting Proteins Database: YER081W, YDR194C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available YDR194C MSS116 DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non...e name MSS116 Prey description DEAD-box protein required for efficient splicing of mitochondrial Group I and

  2. 46 CFR 194.05-5 - Chemicals in the chemistry laboratory.

    Science.gov (United States)

    2010-10-01

    ... labeled as required by 49 CFR part 172. Reagent containers in the laboratory shall be marked to show at... 46 Shipping 7 2010-10-01 2010-10-01 false Chemicals in the chemistry laboratory. 194.05-5 Section....05-5 Chemicals in the chemistry laboratory. (a) Small working quantities of chemical stores in...

  3. Generation of continuous-wave 194 nm laser for mercury ion optical frequency standard

    Science.gov (United States)

    Zou, Hongxin; Wu, Yue; Chen, Guozhu; Shen, Yong; Liu, Qu; Precision measurement; atomic clock Team

    2015-05-01

    194 nm continuous-wave (CW) laser is an essential part in mercury ion optical frequency standard. The continuous-wave tunable radiation sources in the deep ultraviolet (DUV) region of the spectrum is also serviceable in high-resolution spectroscopy with many atomic and molecular lines. We introduce a scheme to generate continuous-wave 194 nm radiation with SFM in a Beta Barium Borate (BBO) crystal here. The two source beams are at 718 nm and 266 nm, respectively. Due to the property of BBO, critical phase matching (CPM) is implemented. One bow-tie cavity is used to resonantly enhance the 718 nm beam while the 266 nm makes a single pass, which makes the configuration easy to implement. Considering the walk-off effect in CPM, the cavity mode is designed to be elliptical so that the conversion efficiency can be promoted. Since the 266 nm radiation is generated by a 532 nm laser through SHG in a BBO crystal with a large walk-off angle, the output mode is quite non-Gaussian. To improve mode matching, we shaped the 266 nm beam into Gaussian modes with a cylindrical lens and iris diaphragm. As a result, 2.05 mW 194 nm radiation can be generated. As we know, this is the highest power for 194 nm CW laser using SFM in BBO with just single resonance. The work is supported by the National Natural Science Foundation of China (Grant No. 91436103 and No. 11204374).

  4. 41 CFR 102-194.40 - For what Standard or Optional forms should an electronic version not be made available?

    Science.gov (United States)

    2010-07-01

    ... Optional forms should an electronic version not be made available? 102-194.40 Section 102-194.40 Public... For what Standard or Optional forms should an electronic version not be made available? All forms should include an electronic version unless it is not practicable to do so. Areas where it may not...

  5. 43 CFR 19.4 - Liaison with other governmental agencies and submission of views by interested persons.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Liaison with other governmental agencies and submission of views by interested persons. 19.4 Section 19.4 Public Lands: Interior Office of the... recommendations as to the suitability or nonsuitability for preservation as wilderness of any roadless area in...

  6. Identification of miR-194-5p as a potential biomarker for postmenopausal osteoporosis

    Directory of Open Access Journals (Sweden)

    Jia Meng

    2015-05-01

    Full Text Available The incidence of osteoporosis is high in postmenopausal women due to altered estrogen levels and continuous calcium loss that occurs with aging. Recent studies have shown that microRNAs (miRNAs are involved in the development of osteoporosis. These miRNAs may be used as potential biomarkers to identify women at a high risk for developing the disease. In this study, whole blood samples were collected from 48 postmenopausal Chinese women with osteopenia or osteoporosis and pooled into six groups according to individual T-scores. A miRNA microarray analysis was performed on pooled blood samples to identify potential miRNA biomarkers for postmenopausal osteoporosis. Five miRNAs (miR-130b-3p, -151a-3p, -151b, -194-5p, and -590-5p were identified in the microarray analysis. These dysregulated miRNAs were subjected to a pathway analysis investigating whether they were involved in regulating osteoporosis-related pathways. Among them, only miR-194-5p was enriched in multiple osteoporosis-related pathways. Enhanced miR-194-5p expression in women with osteoporosis was confirmed by quantitative reverse transcription–polymerase chain reaction analysis. For external validation, a significant correlation between the expression of miR-194-5p and T-scores was found in an independent patient collection comprised of 24 postmenopausal women with normal bone mineral density, 30 postmenopausal women with osteopenia, and 32 postmenopausal women with osteoporosis (p < 0.05. Taken together, the present findings suggest that miR-194-5p may be a viable miRNA biomarker for postmenopausal osteoporosis.

  7. Identification of miR-194-5p as a potential biomarker for postmenopausal osteoporosis.

    Science.gov (United States)

    Meng, Jia; Zhang, Dapeng; Pan, Nanan; Sun, Ning; Wang, Qiujun; Fan, Jingxue; Zhou, Ping; Zhu, Wenliang; Jiang, Lihong

    2015-01-01

    The incidence of osteoporosis is high in postmenopausal women due to altered estrogen levels and continuous calcium loss that occurs with aging. Recent studies have shown that microRNAs (miRNAs) are involved in the development of osteoporosis. These miRNAs may be used as potential biomarkers to identify women at a high risk for developing the disease. In this study, whole blood samples were collected from 48 postmenopausal Chinese women with osteopenia or osteoporosis and pooled into six groups according to individual T-scores. A miRNA microarray analysis was performed on pooled blood samples to identify potential miRNA biomarkers for postmenopausal osteoporosis. Five miRNAs (miR-130b-3p, -151a-3p, -151b, -194-5p, and -590-5p) were identified in the microarray analysis. These dysregulated miRNAs were subjected to a pathway analysis investigating whether they were involved in regulating osteoporosis-related pathways. Among them, only miR-194-5p was enriched in multiple osteoporosis-related pathways. Enhanced miR-194-5p expression in women with osteoporosis was confirmed by quantitative reverse transcription-polymerase chain reaction analysis. For external validation, a significant correlation between the expression of miR-194-5p and T-scores was found in an independent patient collection comprised of 24 postmenopausal women with normal bone mineral density, 30 postmenopausal women with osteopenia, and 32 postmenopausal women with osteoporosis (p osteoporosis.

  8. Study of the Alpha-Decay Chain for7753 194Rn with Relativistic Mean-Field Theory

    Institute of Scientific and Technical Information of China (English)

    SHENG Zong-Qiang; GUO Jian-You

    2008-01-01

    The structures of the nuclei on the alpha-decay chain of 194Rn are investigated in the deformed relativistic mean-field theory with the effective interaction TMA. We put an emphasis on the ground state properties of 194Rn. The calculated alpha-decay energies and lifetimes are both very close to the experimental data for 186pb and 190po. For 194 Rn, the deviations are a little large on both the alpha-decay energy and the lifetime. We also calculate the alpha-decay energies for the isotopes 192~208Rn. The tendency for the change of the alpha-decay energies with neutron number is correctly reproduced in the relativistic mean-field theory (RMF). In general, the RMF theory can give a good description of the alpha decay chain of 194Rn.

  9. Analysis of clinical characteristics of 194 HIV positive pregnant women%194名HIV阳性孕妇临床特征分析

    Institute of Scientific and Technical Information of China (English)

    于兰; 唐志荣; 刘丽芬; 刘燕芬; 杨睿侃; 李繁; 张福杰

    2011-01-01

    Objectives To analyze the demographic, epidemiological, clinical and laboratmy characteristics of 194 HIV positive pregnant women visiting prenatal clinics in Guangxi and to explore the impact of HIV on pregnant women. Methods The data of demographic,epidemiology, clinical and laboratory characteristics of 194 HIV positive pregnant women diagnosed in four cities and counties of Guangxi from October 2008 to February 2009 were analyzed. Results The average age of 194 HIV pregnant women was 26 ± 4.4 years. A majoriiy of them were infected through sexual behavior. 14.4% and 45.9% of them were found at first and third trimester, respectively. Median CD4 count was 317/mL and HIV viral load was 23 600copies/mL when enrolled. There were 54% patients whose CD4 was lower than 350/mL and 19% whose viral load over 100 000 copies/mL. Anemia was common in 61.9% pregnant women, and opportunity infection ( OI ) was found in 16% pregnant women, the main manifestations of which included recmrent fever, skin lesion, respiratory infection,tuberculosis and chronic diarrhea. There were 4.61% and 67.01% HIV positive pregnant women receiving HAART before pregnancy and during pregnancy, and 9.28% of them received cotrimoxazole prophylaxis for OI prevention. Conclusion Early detecting of HIV positive pregnant women and understanding the epidemiological, demographic, clinical and laboratory characteristics of them are the priority strategies of implementing intervention and care for HIV positive pregnant women.%目的 对广西4个市、县在产前门诊发现的194例艾滋病病毒(HIV)阳性孕产妇的人口学、流行病学临床及实验室特征进行描述性分析,了解HIV对孕产妇的影响.方法 针对在2006年10月到2009年2月广西省4个市、县发现的194例HIV阳性孕产妇人口学、流行病学、临床和实验室特征进行分析.结果 194名HIV阳性的孕妇的平均年龄(26±4.4)岁,大部分经性感染,其中孕早期和孕晚

  10. DSAM lifetime measurements for the chiral pair in {sup 194}Tl

    Energy Technology Data Exchange (ETDEWEB)

    Masiteng, P.L.; Bvumbi, S.P. [National Research Foundation, iThemba LABS, PO Box 722, Somerset West (South Africa); University of the Western Cape, Private Bag X17, Bellville (South Africa); University of Johannesburg, PO Box 524, Auckland Park (South Africa); Pasternak, A.A. [A.F. Ioffe Physical-Technical Institute, St.-Petersburg (Russian Federation); Lawrie, E.A.; Shirinda, O.; Lawrie, J.J.; Bark, R.A.; Kheswa, N.Y.; Lieder, E.O.; Lieder, R.M.; Mullins, S.M.; Murray, S.H.T. [National Research Foundation, iThemba LABS, PO Box 722, Somerset West (South Africa); Lindsay, R. [University of the Western Cape, Private Bag X17, Bellville (South Africa); Madiba, T.E.; Sharpey-Schafer, J.F. [National Research Foundation, iThemba LABS, PO Box 722, Somerset West (South Africa); University of the Western Cape, Private Bag X17, Bellville (South Africa); Ndayishimye, J.; Papka, P. [National Research Foundation, iThemba LABS, PO Box 722, Somerset West (South Africa); University of Stellenbosch, Department of Physics, Private Bag X1, Matieland (South Africa); Ntshangase, S.S. [National Research Foundation, iThemba LABS, PO Box 722, Somerset West (South Africa); University of Cape Town, Department of Physics, Private Bag, Rondebosch (South Africa)

    2016-02-15

    Most important for the identification of chiral symmetry in atomic nuclei is to establish a pair of bands that are near-degenerate in energy, but also in B(M1) and B(E2) transition probabilities. Dedicated lifetime measurements were performed for four bands of {sup 194}Tl, including the pair of four-quasiparticle chiral bands with close near-degeneracy, considered as a prime candidate for best chiral symmetry pair. The lifetime measurements confirm the excellent near-degeneracy in this pair and indicate that a third band may be involved in the chiral symmetry scenario. (orig.)

  11. Sum-frequency generation of continuous-wave light at 194 nm.

    Science.gov (United States)

    Berkeland, D J; Cruz, F C; Bergquist, J C

    1997-06-20

    Over 2 mW of continuous-wave tunable 194-nm light is produced by sum-frequency mixing approximately 500 mW of 792-nm and 500 mW of 257-nm radiation in beta-barium borate (BBO). The powers in both fundamental beams are enhanced in separate ring cavities whose optical paths overlap in the Brewster-cut BBO crystal. Due to the higher circulating fundamental powers, the sum-frequency-generated power is nearly 2 orders of magnitude greater than previously reported values.

  12. Multiple superdeformed bands in 194Hg and their dynamical moments of inertia

    International Nuclear Information System (INIS)

    Three superdeformed bands have been observed in 194Hg. The dynamical moment of inertia J(2) of all three bands is observed to increase by 30-40% over the frequency range ℎω=0.1-0.4 MeV. This phenomena can be understood in terms of the gradual alignment of pairs of high-j intruder orbitals within the framework of the cranked Woods-Saxon and Nilsson models including pairing. The calculations together with the observed J(2) behaviour of the three bands indicate that pairing correlations in the superdeformed minimum are rather weak. (orig.)

  13. 3C 40 in Abell 194: can tail radio galaxies exist in a quiescent cluster?

    CERN Document Server

    Sakelliou, I; Jetha, N N

    2007-01-01

    The nearby cluster Abell 194 hosts two luminous, distorted radio galaxies. Both reside within the cluster's core region, being separated in projection by only 100 kpc. It is often suggested that tailed radio galaxies such as these reside in clusters that are under formation and are accreting new material from their outskirts. In this paper we study the intriguing appearance of Abell 194, and test whether the cluster and radio source dynamics are consistent with the cluster formation/merger model. We analyse data from the XMM-Newton satellite and previously unpublished observations with the Very Large Array (VLA), as well as presenting new data from the Giant Metre-Wave Radio Telescope (GMRT). The shape of the jets, and the lack of significant stripping of the galaxies' interstellar media, indicate that the radio galaxies are not moving at the large velocities they would have had if they were falling into the cluster from its outskirts; galaxy velocities of <=300 km s^-1 are adequate instead. A plausible sc...

  14. 19.4%-efficient large-area fully screen-printed silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Gatz, Sebastian; Hannebauer, Helge; Hesse, Rene; Werner, Florian; Schmidt, Arne; Dullweber, Thorsten; Bothe, Karsten [Institute for Solar Energy Hamelin (ISFH), Am Ohrberg 1, 31860 Emmerthal (Germany); Schmidt, Jan; Brendel, Rolf [Institute for Solar Energy Hamelin (ISFH), Am Ohrberg 1, 31860 Emmerthal (Germany); Institute of Solid-State Physics, University of Hannover, Appelstrasse 2, 30167 Hannover (Germany)

    2011-04-15

    We demonstrate industrially feasible large-area solar cells with passivated homogeneous emitter and rear achieving energy conversion efficiencies of up to 19.4% on 125 x 125 mm{sup 2} p-type 2-3 {omega} cm boron-doped Czochralski silicon wafers. Front and rear metal contacts are fabricated by screen-printing of silver and aluminum paste and firing in a conventional belt furnace. We implement two different dielectric rear surface passivation stacks: (i) a thermally grown silicon dioxide/silicon nitride stack and (ii) an atomic-layer-deposited aluminum oxide/silicon nitride stack. The dielectrics at the rear result in a decreased surface recombination velocity of S{sub rear} = 70 cm/s and 80 cm/s, and an increased internal IR reflectance of up to 91% corresponding to an improved J{sub sc} of up to 38.9 mA/cm{sup 2} and V{sub oc} of up to 664 mV. We observe an increase in cell efficiency of 0.8% absolute for the cells compared to 18.6% efficient reference solar cells featuring a full-area aluminum back surface field. To our knowledge, the energy conversion efficiency of 19.4% is the best value reported so far for large area screen-printed solar cells. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  15. Evaporation residue excitation function measurement for 19F + 194,198Pt reactions

    International Nuclear Information System (INIS)

    Nuclear dissipation is one of the active fields in the present day nuclear physics research. Experimental signatures for dissipation are observed through large excess in pre-fission neutrons, γ-ray multiplicities from the compound nucleus, giant dipole resonance (GDR) γ-rays, light charged particles and evaporation residues in comparison to standard statistical model, for the heavy-ion induced fusion-fission or fusion-evaporation reactions (ERs). From the analysis of a large set of experimental data, it is well established that there exists a large dissipation at nuclear temperature above 1 MeV. But most of these probes are not sensitive to the dissipation within saddle. The ER cross-section is a probe which is sensitive to dissipation within the saddle point. Hence, the study of ER cross-section can be helpful in estimating the dissipation effects inside the saddle point. Also the other motivation for these measurements is to see the effect of shell closure on dissipation. With this motivation the evaporation cross-sections for 19F + 194,198Pt are measured at beam energy of 101 to 137.3 MeV. Of the above systems 19F + 194Pt populates 213Fr (N = 126) shell closed compound nucleus (CN) whereas, other system populate 217Fr (N = 130) non-shell closed CN

  16. Compliance of the Waste Isolation Pilot Plant with 40 CFR 194.24(b)

    International Nuclear Information System (INIS)

    This paper presents aspects of DOE's demonstration of compliance with the EPA regulation of the Waste Isolation Pilot Plant (WIPP). The WIPP, a geologic repository for transuranic (TRU) waste, is located 2150 feet below the ground surface in a bedded salt formation about 20 miles east of Carlsbad, NM. Performance of the WIPP as a repository requires that releases to the accessible environment not exceed the limits of the regulation 40 CFR Part 191(1) either when the WIPP is undisturbed, or if there is intrusion into the repository by drilling. In 1996, the EPA promulgated 40 CFR Part 194(2): the implementing regulation for 40 CFR Part 191. The regulatory subsection addressed here, 40 CFR 194.24(b), directs the DOE to identify and analyze the components and characteristics of the TRU waste that can impact performance of the WIPP repository, and thereby possibly impact waste containment. DOE must also analyze those waste characteristics and components that will not affect repository performance

  17. Imunogenicidade da cepa avirulenta RV194-2 do vírus rábico em camundongos

    Directory of Open Access Journals (Sweden)

    Rugimar Marcovistz

    1996-12-01

    Full Text Available O vírus rábico RV194-2, uma variante avirulenta da cepa CVS (Challenge Vírus Standard, produz uma infecção inaparente quando inoculado intracerebralmente em camundongos adultos. Sugerindo que a resposta imunológica do hospedeiro permite a eliminação do vírus do sistema nervoso central. Por esta razão foram estudadas a indução de interferon e a resposta imune humoral em camundongos BALB/c inoculados com vírus RV194-2. Durante a infecção, estes camundongos apresentaram elevados níveis de interferon no plasma e no cérebro com altos títulos de anticorpos neutralizantes anti-rábicos. A 2-5A sintetase. um marcador da ação dos interferons,foi também analisada no cérebro destes animais. Sua atividade, aumentou, paralelamente, á produção de interferon, demonstrando que este interferon é bioquímicamente ativo. O vírus RV194-2 também induziu, 45 dias após sua inoculação, proteção aos animais quando desafiados com a cepa virulenta CVS. Estes resultados demonstram que a cepa RV194-2possui um alto nível imunogênico.RV194-2 rabies virus, an avirulent mutant of CVS strain, induces an inapparent infection limited to the central nervous system (CNS in adult mice inoculated intracerebrally. This fact suggest that immune response of the host is able to eliminate the virus in CNS. For this reason, we have studied the induction of interferon and the humoral immune responses in BALB/c mice after RV194-2 inoculation. These mice presented high levels of interferon in the plasma and in the brain, with elevated levels of neutralizing antirabies antibodies. The 2-5A synthetase, an enzyme marker of interferon action, was analyzed in the brain of inoculated animals. Its enhancement in parallel to the interferon production in the brain, showed biochemical evidence that this interferon is active. Forty five days after RV194-2 virus inoculation, mice were protected against a challenge with the CVS virulent strain. The results presented

  18. Spectral and Temporal Properties of MAXI J1836-194 during 2011 Outburst

    CERN Document Server

    Jana, A; Mondal, S; Chakrabarti, S K; Molla, A A; Chatterjee, D

    2015-01-01

    We study black hole candidate (BHC) MAXI~J1836-194 during its 2011 outburst with Two Component Advective Flow (TCAF) model using RXTE/PCU2 data in $2.5-25$~keV band. From spectral fit, accretion flow parameters such as Keplerian disk rate ($\\dot{m_d}$), sub-Keplerian halo rate ($\\dot{m_h}$), shock location ($X_{s}$) and compression ratio (R) are extracted directly. During the entire phase of the outburst, quasi-periodic oscillations (QPOs) are observed sporadically. From the nature of the variation of accretion rate ratio (ARR=$\\dot{m_h}$ / $\\dot{m_d}$) and QPOs, entire period of the outburst is classified in two spectral states, such as, hard (HS), hard-intermediate (HIMS). Unlike other transient BHCs, no signature of soft (SS) and soft-intermediate (SIMS) spectral states are observed during entire phase of the outburst

  19. Radio monitoring of the hard state jets in the 2011 outburst of MAXI J1836-194

    NARCIS (Netherlands)

    T.D. Russell; J.C.A. Miller-Jones; P.A. Curran; R. Soria; D. Altamirano; S. Corbel; M. Coriat; A. Moin; D.M. Russell; G.R. Sivakoff; T.J. Slaven-Blair; T.M. Belloni; R.P. Fender; S. Heinz; P.G. Jonker; H.A. Krimm; E.G. Körding; D. Maitra; S. Markoff; M. Middleton; S. Migliari; R.A. Remillard; M.P. Rupen; C.L. Sarazin; A.J. Tetarenko; M.A.P. Torres; V. Tudose; A.K. Tzioumis

    2015-01-01

    MAXI J1836−194 is a Galactic black hole candidate X-ray binary that was discovered in 2011 when it went into outburst. In this paper, we present the full radio monitoring of this system during its ‘failed’ outburst, in which the source did not complete a full set of state changes, only transitioning

  20. MicroRNA-194 promotes the growth, migration, and invasion of ovarian carcinoma cells by targeting protein tyrosine phosphatase nonreceptor type 12

    Science.gov (United States)

    Liang, Tian; Li, Liru; Cheng, Yan; Ren, Chengcheng; Zhang, Guangmei

    2016-01-01

    Ovarian carcinoma is the most lethal gynecologic malignancy among women. Ovarian cancer metastasis is the main reason for poor prognosis. MicroRNAs (miRNAs) have been shown to play an important role in tumorigenesis and metastasis in various cancers by affecting the expression of their targets. In this study, we explored the role of miR-194 in ovarian cancer. Real-time polymerase chain reaction assays showed that miR-194 was significantly upregulated in ovarian cancer tissues. Overexpression of miR-194 in ovarian cancer cells promotes cell proliferation, migration, and invasion; in contrast, inhibition of the expression of miR-194 has the opposite effects. Meanwhile, bioinformatics tools were used to identify protein tyrosine phosphatase nonreceptor type 12 (PTPN12) as a potential target of miR-194. The luciferase assay showed that miR-194 directly binds to the 3′-untranslated region of PTPN12. Western blot analysis and quantitative real-time polymerase chain reaction assay revealed that PTPN12 expression was negatively associated with miR-194 expression in both ovarian cancer tissues and cells. Thus, we conclude that miR-194 targets PTPN12 and functions as an oncogene in ovarian cancer cells. This novel pathway may provide a new insight to explain ovarian cancer development and metastasis. PMID:27486333

  1. Primary transitions between the yrast superdeformed band and low-lying normal deformed states in {sup 194}Pb

    Energy Technology Data Exchange (ETDEWEB)

    Hauschild, K.; Bernstein, L.A.; Becker, J.A. [Lawrence Livermore National Lab., CA (United States)] [and others

    1996-12-31

    The observation of one-step `primary` gamma-ray transitions directly linking the superdeformed (SD) states to the normal deformed (ND) low-lying states of known excitation energies (E{sub x}), spins and parities (J{sup {pi}}) is crucial to determining the E{sub x} and J{sup {pi}} of the SD states. With this knowledge one can begin to address some of the outstanding problems associated with SD nuclei, such as the identical band issue, and one can also place more stringent restrictions on theoretical calculations which predict SD states and their properties. Brinkman, et al., used the early implementation of the GAMMASPHERE spectrometer array (32 detectors) and proposed a single, candidate {gamma} ray linking the {sup 194}Pb yrast SD band to the low-lying ND states in {sup 194}Pb. Using 55 detectors in the GAMMASPHERE array Khoo, et al., observed multiple links between the yrast SD band in {sup 194}Hg and the low-lying level scheme and conclusively determined E{sub x} and J of the yrast SD states. Here the authors report on an experiment in which Gammasphere with 88 detectors was used and the E{sub x} and J{sup {pi}} values of the yrast SD states in {sup 194}Pb were uniquely determined. Twelve one-step linking transitions between the yrast SD band and low-lying states in {sup 194}Pb have been identified, including the transition proposed by Brinkman. These transitions have been placed in the level scheme of {sup 194}Pb using coincidence relationships and agreements between the energies of the primary transitions and the energy differences in level spacings. Furthermore, measurements of angular asymmetries have yielded the multipolarities of the primaries which have allowed J{sup {pi}} assignments of the {sup 194}Pb SD states to be unambiguously determined for the first time without a priori assumptions about the character of SD bands. A study performed in parallel to this work using the EUROGAM-II array reports similar, but somewhat less extensive, results.

  2. Regulation of nucleolin expression by miR-194, miR-206, and HuR.

    Science.gov (United States)

    Bose, Sudeep; Tholanikunnel, Tracy E; Reuben, Adrian; Tholanikunnel, Baby G; Spicer, Eleanor K

    2016-06-01

    Nucleolin is a proliferation-associated protein that is overexpressed in multiple types of cancer. The mechanisms leading to overexpression of nucleolin in specific cancers are not fully understood. This study found that nucleolin is notably elevated in breast cancer cell lines MCF-7 and MDA-231 compared to nonmalignant breast epithelial MCF-10A cells. In silico analyses revealed the presence of putative binding sites for microRNAs miR-194 and miR-206 in the 3'-untranslated region (3'-UTR) of Ncl mRNA. Transfection of the three cell lines with pre-miR-194 or pre-miR-206 specifically decreased the Ncl mRNA and protein expression. Treatments of the cells with antagomiR-194 or antagomiR-206 upregulated nucleolin expression ~2- to 3-fold. Co-transfection of cells with a reporter vector containing the Ncl 3'-UTR downstream from the Renilla luciferase gene and pre-miR-194 or pre-miR-206 led to a ~3-fold decrease in Renilla/firefly luciferase activity. Cytoplasmic levels of the RNA-binding protein HuR were higher in MCF-7 and MDA-231 cells than those in MCF-10A cells. RNA immunoprecipitation assays demonstrated that HuR binds to Ncl mRNA in all the three cell types. ShRNA-mediated knock-down of HuR induced a decrease in nucleolin expression, while exogenous expression of HuR led to upregulation of nucleolin expression. Analysis of the polysome-monosome distribution of Ncl mRNA in HuR knock-down cells demonstrated that HuR enhances the translation efficiency of Ncl mRNA. These findings demonstrate that nucleolin expression is down-regulated by miR-194 and miR-206 and upregulated by HuR. PMID:27221739

  3. a194yb.m77t and a194yb.h77t: MGD77T data and header files for single-beam bathymetry for field activity A-1-94-YB in Yakutat Bay and Yakutat Sea Valley, Alaska from 08/05/1994 to 08/08/1994

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with GPS navigation data was collected as part of the U.S. Geological Survey cruise A-1-94-YB. The cruise was conducted in Yakutat...

  4. k194hw.m77t and k194hw.h77t: MGD77T data and header files for single-beam bathymetry data for field activity K-1-94-HW in Mamala Bay, Offshore Honolulu, Oahu, Hawaii from 05/10/1994 to 05/16/1994

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with DGPS navigation data was collected as part of the U.S. Geological Survey cruise K-1-94-HW. The cruise was conducted in Oahu,...

  5. a194gb.m77t and a194gb.h77t: MGD77T data and header files for single-beam bathymetry data for field activity A-1-94-GB in Prince William Sound, Yakutat Bay, Glacier Bay and Icy Strait, Alaska from 08/08/1994 to 08/17/1994

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with GPS navigation data was collected as part of the U.S. Geological Survey cruise A-1-94-GB. The cruise was conducted in Prince...

  6. p194ar.m77t and p194ar.h77t: MGD77T data and header files for single-beam bathymetry data for field activity P-1-94-AR in Arctic Ocean from 07/25/1994 to 08/30/1994

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with SINS navigation data was collected as part of the U.S. Geological Survey cruise P-1-94-AR. The cruise was conducted in...

  7. Overexpression of OsCYP19-4 increases tolerance to cold stress and enhances grain yield in rice (Oryza sativa).

    Science.gov (United States)

    Yoon, Dae Hwa; Lee, Sang Sook; Park, Hyun Ji; Lyu, Jae Il; Chong, Won Seog; Liu, Jang Ryol; Kim, Beom-Gi; Ahn, Jun Cheul; Cho, Hye Sun

    2016-01-01

    AtCYP19-4 (also known as CYP5) was previously identified as interacting in vitro with GNOM, a member of a large family of ARF guanine nucleotide exchange factors that is required for proper polar localization of the auxin efflux carrier PIN1. The present study demonstrated that OsCYP19-4, a gene encoding a putative homologue of AtCYP19-4, was up-regulated by several stresses and showed over 10-fold up-regulation in response to cold. The study further demonstrated that the promoter of OsCYP19-4 was activated in response to cold stress. An OsCYP19-4-GFP fusion protein was targeted to the outside of the plasma membrane via the endoplasmic reticulum as determined using brefeldin A, a vesicle trafficking inhibitor. An in vitro assay with a synthetic substrate oligomer confirmed that OsCYP19-4 had peptidyl-prolyl cis-trans isomerase activity, as was previously reported for AtCYP19-4. Rice plants overexpressing OsCYP19-4 showed cold-resistance phenotypes with significantly increased tiller and spike numbers, and consequently enhanced grain weight, compared with wild-type plants. Based on these results, the authors suggest that OsCYP19-4 is required for developmental acclimation to environmental stresses, especially cold. Furthermore, the results point to the potential of manipulating OsCYP19-4 expression to enhance cold tolerance or to increase biomass. PMID:26453745

  8. Tidal bridge and tidal dwarf candidates in the interacting system Arp194

    CERN Document Server

    Zasov, Anatoly; Egorov, Oleg; Afanasiev, Viktor

    2016-01-01

    Arp194 is a system of recently collided galaxies, where the southern galaxy (S) passed through the gaseous disc of the northern galaxy (N) which in turn consists of two close components. This system is of special interest due to the presence of regions of active star-formation in the bridge between galaxies, the brightest of which (the region A) has a size of at least 4 kpc. We obtained three spectral slices of the system for different slit positions at the 6-m telescope of SAO RAS. We estimated the radial distribution of line-of-sight velocity and velocity dispersion as well as the intensities of emission lines and oxygen abundance $12+\\log(\\mathrm{O/H})$. The gas in the bridge is only partially mixed chemically and spatially: we observe the O/H gradient with the galactocentric distances both from S and N galaxies and a high dispersion of O/H in the outskirts of N-galaxy. Velocity dispersion of the emission-line gas is the lowest in the star-forming sites of the bridge and exceeds 50-70 km/s in the disturbed...

  9. Long noncoding RNA H19 contributes to gallbladder cancer cell proliferation by modulated miR-194-5p targeting AKT2.

    Science.gov (United States)

    Wang, Shou-Hua; Wu, Xiao-Cai; Zhang, Ming-Di; Weng, Ming-Zhe; Zhou, Di; Quan, Zhi-Wei

    2016-07-01

    Gallbladder cancer (GBC) is a highly malignant cancer with poor prognosis. Although long noncoding RNA (lncRNA) H19 has been reported to play vital role in many human cancers, whether it is involved in GBC proliferation is still unknown. This study was designed to explore the effect of H19 in GBC cell proliferation. The expression of H19 and AKT2 were significantly elevated in GBC tissues, and the level of miR-194-5p is markedly decreased. Moreover, the RNA levels of H19 and AKT2 were positively correlated, and H19 elevation was significantly associated with tumor size. Cell proliferation decreased significantly after knockdown of H19 in GBC-SD and NOZ cells and after knockdown of AKT2 in NOZ cells. Results from cell cycle studies indicated that the S phase were significantly decreased after knockdown of H19 in NOZ cells but significantly elevated after overexpression of H19 in GBC-SD cells. Furthermore, knockdown of H19 upregulated miR-194-5p levels, yet significantly decreased miR-194-5p targeting AKT2 gene expression in NOZ cells. Inhibitor against miR-194-5p reversed these effects. In addition, overexpression of H19 in GBC-SD cells downregulated miR-194-5p and markedly increased AKT2 expression, and miR-194-5p mimic reversed these effects. Eventually, GBC cells were arrested in G0/G1-phase after H19 knockdown, inhibition of miR-194-5p markedly promoted cells into S-phase and co-transfection of siH19, and miR-194-5p inhibitor exerted mutually counter-regulated effects on cell cycle. These results suggested that H19/miR-194-5p/AKT2 axis regulatory network might modulate cell proliferation in GBC. PMID:26803515

  10. 194例婴幼儿麻疹临床及流行病学特征的分析%An analysis of clinical and epidemiological features of 194 cases of infants with measles

    Institute of Scientific and Technical Information of China (English)

    刘杰兵

    2015-01-01

    Objective To explore the clinical and epidemiological features of 194 cases of infants with measles in Huadu. Methods Retrospective analysis of clinical data of 194 cases of infants with measles in Huadu from 2010 to 2014 were made,and it was analyzed by descriptive epidemiological methods. Results 194 infants with measles were diagnosed in Huadu from 2010 to 2014.Morbidity in the infants under 1 years old was highest (P < 0.05),and the onset of the disease were mainly in March and April.Morbidity of floating population was significantly higher than that of local population (P < 0.05),and Morbidity of people without history of vaccination and people with measles contact was significantly higher (P < 0.05). Conclusion Measures can be taken to control the morbidity of measles effectively including good seasonal prevention,expanding measles immunization timely,raising the vaccination rate of floating and rural population and strengthening vaccination of high-risk population.%目的:探讨花都区婴幼儿麻疹临床及流行病学特点。方法回顾性分析花都区2010~2014年194例婴幼儿麻疹的临床资料,并进行描述性流行病学分析。结果2010年~2014花都区共出现婴幼儿麻疹194例,年龄<1岁发病率最高(P <0.05),发病时间主要集中于3、4月份,流动人口发病率明显高于本地户籍人口(P <0.05),无免疫接种史和有麻疹接触史者发病率明显要高(P <0.05)。结论做好季节性预防,及时扩大麻疹免疫接种范围,提高流动人口和农村人口的接种率,加强对高危人群免疫接种,可达到有效控制麻疹发病率的作用。

  11. [Induced abortion. Epidemiological study after eight years of enforcement of Law 194].

    Science.gov (United States)

    Danero, S; Capitani, S; La Rosa, R; Morgante, G; Marsiglietti, C; Turillazzi, E; Oliveti, C; Ricci, M G

    1987-01-01

    The authors describe a study of induced abortions performed at the obstetric and gynecological university clinic in Siena, Italy, during the period 6/1/84-5/31/86, contrasting data with the experience of the first two years (6/1/78-5/31/80) of existence of law no. 194 introduced in 1978. The law legalized abortion--until then considered a social wound on society--thus making abortions more easily quantifiable from an epidemiological point of view. Since that initial period the socio- sanitary reality has changed substantially, i.e., a national progressive increase in the number of abortions was followed by a downward trend that has persisted since then, due to greater openness toward the use of contraceptive methods, in the mass media. A correct evaluation of the number of abortions cannot be obtained due to continued secret abortions. The study reflects the national trend, since during the first period, 2171 induced abortions were performed versus 1450 during the second period (a 13.14% decrease). Questionnaires asked patients about their age, geographic origin, occupation, marital status, week of pregnancy, possible previously induced abortions, length of stay in the hospital, and birth control method used at the time of induced abortion. The most significant variations in the parameters studied for the two periods demonstrated reduced waiting periods before an induced abortion operation was performed (during early pregnancy), a reduced number of requests by patients living in remote areas of the province, reduced time spent as inpatient in the clinic, and an increased percentage of women with previously induced abortions. The number of women preferring a certain type of birth control method during the two periods is comparable, except a slight increase was noted for those using IUD. It is concluded that there are still large lacunae in the area of abortion prevention in Italy, e.g., coitus interruptus is still widely practiced. PMID:12283378

  12. Tidal bridge and tidal dwarf candidates in the interacting system Arp194

    Science.gov (United States)

    Zasov, Anatoly V.; Saburova, Anna S.; Egorov, Oleg V.; Afanasiev, Viktor L.

    2016-11-01

    Arp194 is a system of recently collided galaxies, where the southern galaxy (S) passed through the gaseous disc of the northern galaxy (N) which in turn consists of two close components. This system is of special interest due to the presence of regions of active star formation in the bridge between galaxies, the brightest of which (the region A) has a size of at least 4 kpc. We obtained three spectral slices of the system for different slit positions at the 6-m telescope of SAO RAS. We estimated the radial distribution of line-of-sight velocity and velocity dispersion as well as the intensities of emission lines and oxygen abundance 12 + log (O/H). The gas in the bridge is only partially mixed chemically and spatially: we observe the O/H gradient with the galactocentric distances both from S and N galaxies and a high dispersion of O/H in the outskirts of N-galaxy. Velocity dispersion of the emission-line gas is the lowest in the star-forming sites of the bridge and exceeds 50-70 km s-1 in the disturbed region of N-galaxy. Based on the SDSS photometrical data and our kinematical profiles we measured the masses of stellar population and the dynamical masses of individual objects. We confirm that the region A is the gravitationally bound tidal dwarf with the age of 107-108 yr, which is falling on to the parent S-galaxy. There is no evidence of the significant amount of dark matter in this dwarf galaxy.

  13. XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Chiang, Chien-I [School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan (China); Huang, Ya-Li [Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (China); Chen, Wei-Jen [School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan (China); Shiue, Horng-Sheng [Department of Chinese Medicine, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan (China); Huang, Chao-Yuan; Pu, Yeong-Shiau [Department of Urology, National Taiwan University Hospital, College of Medicine National Taiwan University, Taipei, Taiwan (China); Lin, Ying-Chin [Department of Family Medicine, Shung Ho Hospital, Taipei Medical University, New Taipei, Taiwan (China); Department of Health Examination, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan (China); Division of Family Medicine, School of Medicine, Taipei Medical University, Taipei, Taiwan (China); Hsueh, Yu-Mei, E-mail: ymhsueh@tmu.edu.tw [School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan (China); Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (China)

    2014-09-15

    The association between DNA repair gene polymorphisms and bladder cancer has been widely studied. However, few studies have examined the correlation between urothelial carcinoma (UC) and arsenic or its metabolites. The aim of this study was to examine the association between polymorphisms of the DNA repair genes, XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln, with urinary arsenic profiles and UC. To this end, we conducted a hospital-based case–control study with 324 UC patients and 647 age- and gender-matched non-cancer controls. Genomic DNA was used to examine the genotype of XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln by PCR-restriction fragment length polymorphism analysis (PCR-RFLP). Urinary arsenic profiles were measured by high performance liquid chromatography (HPLC) linked with hydride generator and atomic absorption spectrometry. The XRCC1 399 Gln/Gln and 194 Arg/Trp and Trp/Trp genotypes were significantly related to UC, and the odds ratio (OR) and 95% confidence interval (95%CI) were 1.68 (1.03–2.75) and 0.66 (0.48–0.90), respectively. Participants with higher total urinary arsenic levels, a higher percentage of inorganic arsenic (InAs%) and a lower percentage of dimethylarsinic acid (DMA%) had a higher OR of UC. Participants carrying XRCC1 risk diplotypes G-C/G-C, A-C/A-C, and A-T/G-T, and who had higher total arsenic levels, higher InAs%, or lower DMA% compared to those with other XRCC1 diplotypes had a higher OR of UC. Our results suggest that the XRCC1 399 Gln/Gln and 194 Arg/Arg DNA repair genes play an important role in poor arsenic methylation capacity, thereby increasing the risk of UC in non-obvious arsenic exposure areas. - Highlights: • The XRCC1 399Gln/Gln genotype was significantly associated with increased OR of UC. • The XRCC1 194 Arg/Trp and Trp/Trp genotype had a significantly decreased OR of UC. • Combined effect of the XRCC1 genotypes and poor arsenic methylation capacity on

  14. XRCC1 Arg194Trp and Arg399Gln polymorphisms and arsenic methylation capacity are associated with urothelial carcinoma

    International Nuclear Information System (INIS)

    The association between DNA repair gene polymorphisms and bladder cancer has been widely studied. However, few studies have examined the correlation between urothelial carcinoma (UC) and arsenic or its metabolites. The aim of this study was to examine the association between polymorphisms of the DNA repair genes, XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln, with urinary arsenic profiles and UC. To this end, we conducted a hospital-based case–control study with 324 UC patients and 647 age- and gender-matched non-cancer controls. Genomic DNA was used to examine the genotype of XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, and XPD Lys751Gln by PCR-restriction fragment length polymorphism analysis (PCR-RFLP). Urinary arsenic profiles were measured by high performance liquid chromatography (HPLC) linked with hydride generator and atomic absorption spectrometry. The XRCC1 399 Gln/Gln and 194 Arg/Trp and Trp/Trp genotypes were significantly related to UC, and the odds ratio (OR) and 95% confidence interval (95%CI) were 1.68 (1.03–2.75) and 0.66 (0.48–0.90), respectively. Participants with higher total urinary arsenic levels, a higher percentage of inorganic arsenic (InAs%) and a lower percentage of dimethylarsinic acid (DMA%) had a higher OR of UC. Participants carrying XRCC1 risk diplotypes G-C/G-C, A-C/A-C, and A-T/G-T, and who had higher total arsenic levels, higher InAs%, or lower DMA% compared to those with other XRCC1 diplotypes had a higher OR of UC. Our results suggest that the XRCC1 399 Gln/Gln and 194 Arg/Arg DNA repair genes play an important role in poor arsenic methylation capacity, thereby increasing the risk of UC in non-obvious arsenic exposure areas. - Highlights: • The XRCC1 399Gln/Gln genotype was significantly associated with increased OR of UC. • The XRCC1 194 Arg/Trp and Trp/Trp genotype had a significantly decreased OR of UC. • Combined effect of the XRCC1 genotypes and poor arsenic methylation capacity on

  15. Adverse allergic reactions to linear ionic gadolinium-based contrast agents: experience with 194, 400 injections

    International Nuclear Information System (INIS)

    Aim: To report the authors' experience with the administration of four gadolinium-based contrast agents (GBCA; gadopentetate dimeglumine, gadofosveset trisodium, gadoxetate disodium and gadobenate dimeglumine) in a large study population at a single, large academic medical centre. Materials and methods: The institutional review board approved this retrospective study in which data in the electronic incident reporting system were searched. A total of 194, 400 intravenous administrations of linear ionic GBCAs were assessed for the incidence of adverse reactions and risk factors from 1 January 2007 to 14 January 2014. The severity of reactions (mild, moderate, and severe), patient type (outpatients, inpatients, and emergency), examination type, and treatment options were also investigated. Results: In total, 204/194400 (0.1%) patients (mean age 45.7 ± 14.9) showed adverse reactions, consisting of 6/746 (0.80%), 10/3200 (0.31%), 14/6236 (0.22%) and 174/184218 (0.09%), for gadofosveset trisodium, gadoxetate disodium, gadobenate dimeglumine, and gadopentetate dimeglumine, respectively. An overall significant difference was found between different GBCAs regarding the total number of reactions (p < 0.0001). When comparing the GBCAs together, significant differences were found between gadofosveset trisodium versus gadopentetate dimeglumine (p < 0.0001), gadofosveset trisodium versus gadobenate dimeglumine (p = 0.0051), gadoxetate disodium versus gadopentetate dimeglumine (p < 0.0001) and gadopentetate dimeglumine versus gadobenate dimeglumine (p = 0.0013). Rate of reaction was higher in females (F: 146/113187, 0.13%/M: 58/81213, 0.07%; p < 0.0001). Rate of reactions was higher in outpatient (180/158885, 0.11%), emergency (10/10413, 0.10%), and inpatients (14/25102, 0.05%), respectively (p < 0.0001). Most of the patients had mild symptoms 171/204 (83.8%). Abdomen–pelvis, liver, and thoracic examinations had highest rates of reactions (0.17 versus 0

  16. Incidence of HBV, HCV and syphilis co-infections among 194 HIV-infected pregnant women%194例HIV阳性孕妇HBV HCV及梅毒合并感染状况分析

    Institute of Scientific and Technical Information of China (English)

    于兰; 桂秀枝; 蒙秀宁; 班子淇; 鲁鸿艳; 李文英; 张福杰

    2011-01-01

    目的 了解广西艾滋病病毒(HIV)阳性孕妇合并感染乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒状况,为医疗部门及相关部门采取有效的措施,实施母婴阻断、提高人口素质提供科学的依据.方法 对广西贺州、柳州、南宁和横县发现的194名HIV阳性孕妇的HBV、HCV及梅毒合并感染状况进行检测分析.结果 在调查的194名HIV阳性孕妇中,HIV/HCV、HIV/HBV和HIV/梅毒合并感染率分别为14.14%、9.42%和5.24%.2.62%和1.05%的妇女分别有HIV/HBV/HCV和HIV/HCV/梅毒混合感染,吸毒是HIV/HCV合并感染的危险因素,HIV/HBV合并感染存在地区差异.结论 研究地区HIV阳性孕妇的HBV、HCV及梅毒感染率显著高于普通孕妇,应早期发现并采取有效的干预措施以预防母婴垂直传播.%Objective To learn about the incidence of HBV, HCV and syphilis co-infections among pregnant women infected with HIV in Guangxi so as to provide scientific evidences for adopting effective interventions to interrupt MTCT and improve quality of the population. Methods The data collected from 194 HIV positive pregnant women in Hezhou, Liuzhou and Nanning cities and Heng county of Guangxi were analyzed. Results Among the 194 HIV-infected pregnant women, the co-infection rates of HIV/HCV, HIV/HBV and HIV/syphilis were 14. 14%, 9. 42% and 5. 24% , respectively; 2. 62% and 1. 05% of the women had co-infections of HIV/HBV/HCV and HIV/ HCV/ syphilis, respectively. Drug use was the risk factor for HIV/HCV co-infection and the co-infection of HIV/ HCB had regional variations. Conclusion The incidence of HBV, HCV and syphilis co-infections in HIV-infected pregnant women are obviously higher than in general pregnant women in the areas under study. It is urgent to detect HIV positive pregnant women at an early stage and take effective interventions for the prevention of vertical mother to child transmission.

  17. Fission excitation function for 19F + 194,196,198Pt at near and above barrier energies

    Directory of Open Access Journals (Sweden)

    Singh Varinderjit

    2015-01-01

    Full Text Available Fission excitation functions for 19F + 194,196,198Pt reactions populating 213,215,217Fr compound nuclei are reported. Out of these three compound nuclei, 213Fr is a shell closed (N=126 compound nucleus and the other two are away from the shell closure. From a comparison of the experimental fission cross-sections with the statistical model predictions, it is observed that the fission cross-sections are underestimated by the statistical model predictions using shell corrected finite range rotating liquid drop model (FRLDM fission barriers. Further the FRLDM fission barriers are reduced to fit the fission cross-sections over the entire measured energy range.

  18. Determination of effective resonance energy for the 193Ir(n,γ)194Ir reaction by the cadmium ratio method

    Science.gov (United States)

    Budak, Mustafa Guray; Karadag, Mustafa; Yücel, Haluk

    2016-04-01

    In this work, the effective resonance energy, Ebarr -value for the 193Ir(n,γ)194Ir reaction was measured using cadmium ratio method. A dual monitor (197Au-98Mo), which has convenient resonance properties, was employed for characterization of the irradiation sites. Then analytical grade iridium oxide samples diluted with CaCO3 to lower neutron self-shielding effect stacked in small cylindrical Teflon boxes were irradiated once with a 1 mm thick Cd cylindrical box placed in a thermalized neutron field of an 241Am-Be neutron source then without it. The activities produced in samples during 193Ir(n,γ)194Ir reaction were measured using a p-type HPGe detector γ-ray spectrometer with a 44.8% relative efficiency. The correction factors for thermal, epithermal neutron self-shielding (Gth, Gepi), true coincidence summing (Fcoi) and gamma-ray self-absorption (Fs) effects were determined with appropriate approaches and programs. Thus, the experimental Ebarr -value was determined to be 2.65 ± 0.61 eV for 193Ir target nuclide. The recent data for Q0 and FCd values for Ebarr determination were based on k0-NAA online database. The present experimental Ebarr value was calculated and compared with more recent values for Q0 and FCd for 193Ir. Additionally, the Ebarr -values was theoretically calculated from the up-to-date resonance data obtained from ENDF/B VII library using two different approaches. Since there is no experimentally determined Ebarr -value for the 193Ir isotope, the results are compared with the calculated ones given in the literature.

  19. A Clinical Analysis of 194 Cases of Diffuse Large B-cell Lymphoma%弥漫大B细胞淋巴瘤194例临床分析

    Institute of Scientific and Technical Information of China (English)

    敬小梅; 吴萍; 李力; 熊竹娟; 任苑蓉; 魏雯; 张智慧

    2015-01-01

    Objective:To analyze the clinical chracteristics,therapeutic approach of diffuse large B-cell lymphoma (DLBCL),and to explore the influence factors on the therapeutic effect and prognosis of DLBCL.Methods:A total of 194 DLBCL patients treated in Sichuan Cancer Hospital from 2009 to 2014 were selected,the general clinical characteristics were analyzed to determine the relationship of relevant factors with therapeutic effect and prognosis.The patients were trea-ted with chemotherapy or chemoradiotherapy.The chemotherapy regimens included CHOP and R-CHOP.Results:The me-dian age of the 194 patients was 53 years.The ratio of male:female was 1.66:1.Among 184 patients who accepted treat-ment,68 cases(37.0%)got complete remission (CR)and 72 cases(39.1%)got partial remission (PR)after treatment with an effective rate of 76.1% in all.Univariate analysis showed that the complications of patients、extranodal involve-ment、the serum level of LDH、B symptom、bulky disease、the level of hemoglobin、the clinical stage and cell origins were im-portant influence factors for curative effect.The extranodal involvement、bulky disease and the clinical stage had significant influence on the survival rate of patients (P <0.05).In Cox multivariable analysis,the clinical factors including clinical stage and bulky disease were independent predicting factors for overall survival(OS)(P <0.05).R-CHOP can extend the OS of patients remarkably(P <0.05).Conclusion:DLBCL commonly occurs in male patients at middle ages.The clinical stage and bulky disease are independent factors for the OS of DLBCL.R-CHOP may be the best effective approach for treat-ment of this disease.%目的:分析弥漫大 B 细胞淋巴瘤(DLBCL)的临床特征和治疗方法,探讨 DLBCL 的疗效及预后影响因素。方法:对我院2009~2014年收治的194例 DLBCL 的临床资料进行回顾性分析,以确定相关因素与疗效及预后的关系。治疗方法包括单纯化疗及

  20. Association of XRCC1 Trp194 allele with risk of breast cancer, and Ki67 protein status in breast tumor tissues

    Science.gov (United States)

    Jalali, Chiya; Ghaderi, Bayazid; Amini, Sabrieh; Abdi, Mohammad; Roshani, Daem

    2016-01-01

    Objectives: To evaluate the role of this polymorphism as a risk factor for breast cancer in Kurdish patients and to investigate the possible association between Arg194Trp x-ray repair cross-complementing group 1 (XRCC1) gene polymorphisms with clinical and histopathological outcomes of patients with breast cancer. Methods: A total of 100 breast cancer patients and 200 cancer-free controls in Kurdish population of Kurdistan state admitted to Tohid Hospital, Sanandaj, Kurdistan, Iran between January 2012 and May 2015 were enrolled in this cross-sectional study. Tissue expression of estrogen receptor (ER), progesteron receptor (PR), human epidermal growth factor receptor 2 (Her2/neu), and Ki67 were evaluated by immunohistochemistry (IHC). The Arg194Trp genotypes were determined by polymerase chain reaction- restriction fragment length polymorphism method. Results: Our data showed that the risk for breast cancer increased significantly among the Trp variant of XRCC1. Statistically significant association was found between codon 194 polymorphisms and tissue expression of Ki67. Conclusion: The Trp allele of codon 194 XRCC1 is a potential risk factor for breast cancer in Kurdish ethnicity. Furthermore, effect of this polymorphism on clinical and histological features of breast cancer was significant. PMID:27279507

  1. 产后早期盆底功能恢复情况194例分析%Analysis of early pelvic function recovery condition after delivery in 194 puerperae

    Institute of Scientific and Technical Information of China (English)

    折瑞莲; 魏晓萍; 汪杨; 苏放明

    2011-01-01

    Objective To discuss the situation and feature of early pelvic function recovery after delivery. Methods One hundred and ninety-four puerperae after delivery 6 - 8 weeks who outpatients in department of obsietrics from 2010 october to november and inpatient delivery in department of obstetrics in Shenzhen People's Hospital were selected , pelvic function was checked by the specialist,including conventional gynaecological check-up,pelvic floor muscle strength assessment by hand and pelvic organ prolapsed quantitative score, the urine mat experiment made for had history of urinary leakage person. Results Among the 194 puerperae,146 puerperae ( 75.26% ) had pelvic organ prolapse,42 puerperae (21.65% ) had postpartum stress urinary incontinence. All the patients who had pelvic organ prolapse suffered from anterior vaginal wall prolapse , in which 66.44% (97/146) were of grade Ⅰ ,33.56% (49/146) were of grade Ⅱ . Anterior vaginal wall prolapse combined with pos terior vaginal wall prolapse accounted for 4.79% ( 7/146) , all were grade Ⅰ ;Anterior vaginal prolapse combined with uterine prolapse accounted for 11.64% ( 17/146) , all were grade Ⅰ . One puerperae ( 0.68% ) had anterior vaginal wall prolapse combined with posterior vaginal wall prolapse and uterine prolapse,for Ⅰ degree of prolapse. Conclusion The incidence of female pelvic floor dysfunction is high on the early postpartum,especially anterior vaginal wall prolapse and stress urinary in continence. Luckily,most of them are mild. Therefore,emphasis should be put on pelvic floor reeducation on the early postpar tum , in order to improve quality of their lives.%目的 探讨女性产后早期盆底功能恢复的情况及特点.方法 选择在深圳市人民医院产科住院分娩,且于2010年10月至11月在产科门诊就诊的产后6~8周产妇194例,由专人负责行盆底功能检查,包括常规妇科检查、手测盆底肌力评定及盆腔器官脱垂定量评分,有漏尿

  2. Radio monitoring of the hard state jets in the 2011 outburst of MAXI J1836-194

    CERN Document Server

    Russell, T D; Curran, P A; Soria, R; Altamirano, D; Corbel, S; Coriat, M; Moin, A; Russell, D M; Sivakoff, G R; Slaven-Blair, T J; Belloni, T M; Fender, R P; Heinz, S; Jonker, P G; Krimm, H A; Kording, E G; Maitra, D; Markoff, S; Middleton, M; Migliari, S; Remillard, R A; Rupen, M P; Sarazin, C L; Tetarenko, A J; Torres, M A P; Tudose, V; Tzioumis, A K

    2015-01-01

    MAXI J1836-194 is a Galactic black hole candidate X-ray binary that was discovered in 2011 when it went into outburst. In this paper, we present the full radio monitoring of this system during its `failed' outburst, in which the source did not complete a full set of state changes, only transitioning as far as the hard intermediate state. Observations with the Karl G. Jansky Very Large Array (VLA) and Australia Telescope Compact Array (ATCA) show that the jet properties changed significantly during the outburst. The VLA observations detected linearly polarised emission at a level of ~1% early in the outburst, increasing to ~3% as the outburst peaked. High-resolution images with the Very Long Baseline Array (VLBA) show a ~15 mas jet along the position angle $-21 \\pm 2^\\circ$, in agreement with the electric vector position angle found from our polarisation results ($-21 \\pm 4^\\circ$), implying that the magnetic field is perpendicular to the jet. Astrometric observations suggest that the system required an asymme...

  3. M1 transitions between superdeformed states in {sup 194,195}Tl: The fingerprint of the i{sub 13/2} proton intruder orbital

    Energy Technology Data Exchange (ETDEWEB)

    Azaiez, F.; Duprat, J.; Sharpey-Schafer, J.F.; Aiche, M.; Bastin, G.; Beausang, C.W.; Bourgeois, C.; Clark, R.M.; Deloncle, I.; Duffait, R.; Gale, S.J.; Gall, B.; Hannachi, F.; Hibbert, I.; Joyce, M.J.; Kaci, A.; Kelly, W.H.; Korichi, A.; Le Coz, Y.; Meyer, M.; Perrin, N.; Poffe, N.; Porquet, M.G.; Redon, N.; Sergolle, H.; Schuck, C.; Simpson, J.; Wadsworth, R. [Inst. de Physique Nucleaire, 91 Orsay (France)]|[Oliver Lodge Lab., Univ. of Liverpool (United Kingdom)]|[C.S.N.S.M., IN2P3-CNRS, 91 Orsay (France)]|[Nuclear Structure Facility, Daresbury Lab., Daresbury, Warrington (United Kingdom)]|[Inst. de Physique Nucleaire de Lyon, IN2P3-CNRS, Univ. Claude Bernard, 69 Villeurbanne (France)]|[Dept. of Physics, Univ. of York (United Kingdom)]|[Iowa State Univ., Ames, IA (United States)]|[Univ. of Oxford, Dept. of Physics (United Kingdom)

    1995-12-31

    Recent data from the EUROGAM array have revealed dipole transitions linking signature partner superdeformed bands in {sup 194}Tl and {sup 195}Tl nuclei. Measurements of the decay branching ratios, taken together with the average quadrupole moment of the neighboring superdeformed nuclei, enable the absolute M1 strengths to be determined. From these data and using the strong coupling model, we find that two SD bands in {sup 195}Tl are due to the 81st proton being in the [642]5/2{sup +} orbital and four from the six SD bands in {sup 194}Tl correspond to a configuration where the intrinsic spins of the single proton and single neutron are aligned. (orig.).

  4. 78 FR 19985 - Modification of VOR Federal Airways V-68, V-76, V-194, and V-548 in the Vicinity of Houston, TX

    Science.gov (United States)

    2013-04-03

    ... published in FAA Order 7400.9W (77 FR 50907, August 23, 2012), the FAA is amending the V-68, V-76, V-194... Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  5. Synergetic Integration of Cu1.94S-ZnxCd1-xS Heteronanorods for Enhanced Visible-Light-Driven Photocatalytic Hydrogen Production.

    Science.gov (United States)

    Chen, Yueguang; Zhao, Shu; Wang, Xian; Peng, Qing; Lin, Rui; Wang, Yu; Shen, Rongan; Cao, Xing; Zhang, Libo; Zhou, Gang; Li, Jun; Xia, Andong; Li, Yadong

    2016-04-01

    In this Communication, we present the integration of synergetic designs into high-quality, well-defined Cu1.94S-ZnxCd1-xS heteronanorods (0 ≤ x ≤ 1) for enhanced photocatalytic hydrogen evolution. These heteronanorods possess two light absorbers, intimate heterointerfaces, tunable band gaps over a wide range, and uniform one-dimensional morphology. As verified by experimental and density functional theory studies, these heteronanorods with continuous composition adjustment fully exploit the benefits of both interfacial charge separation and optimized band alignments. Even without any cocatalysts, Cu1.94S-Zn0.23Cd0.77S heteronanorods exhibit efficient hydrogen production activity (7735 μmol h(-1) g(-1)) under visible-light irradiation (λ > 420 nm), representing a 59-fold enhancement compared with the pristine CdS catalyst. Meanwhile, deposition of a Pt cocatalyst on the Cu1.94S-ZnxCd1-xS surface substantially enhances the hydrogen production performance (13 533 μmol h(-1) g(-1)) with an apparent quantum efficiency of 26.4% at 420 nm, opening up opportunities to promote the overall photocatalytic performance using rationally designed nanostructures. PMID:26998730

  6. Synergetic Integration of Cu1.94S-ZnxCd1-xS Heteronanorods for Enhanced Visible-Light-Driven Photocatalytic Hydrogen Production.

    Science.gov (United States)

    Chen, Yueguang; Zhao, Shu; Wang, Xian; Peng, Qing; Lin, Rui; Wang, Yu; Shen, Rongan; Cao, Xing; Zhang, Libo; Zhou, Gang; Li, Jun; Xia, Andong; Li, Yadong

    2016-04-01

    In this Communication, we present the integration of synergetic designs into high-quality, well-defined Cu1.94S-ZnxCd1-xS heteronanorods (0 ≤ x ≤ 1) for enhanced photocatalytic hydrogen evolution. These heteronanorods possess two light absorbers, intimate heterointerfaces, tunable band gaps over a wide range, and uniform one-dimensional morphology. As verified by experimental and density functional theory studies, these heteronanorods with continuous composition adjustment fully exploit the benefits of both interfacial charge separation and optimized band alignments. Even without any cocatalysts, Cu1.94S-Zn0.23Cd0.77S heteronanorods exhibit efficient hydrogen production activity (7735 μmol h(-1) g(-1)) under visible-light irradiation (λ > 420 nm), representing a 59-fold enhancement compared with the pristine CdS catalyst. Meanwhile, deposition of a Pt cocatalyst on the Cu1.94S-ZnxCd1-xS surface substantially enhances the hydrogen production performance (13 533 μmol h(-1) g(-1)) with an apparent quantum efficiency of 26.4% at 420 nm, opening up opportunities to promote the overall photocatalytic performance using rationally designed nanostructures.

  7. 194例甲基苯丙胺滥用者卡特尔16项人格特征分析%194 cases of methamphetamine abusers Cattell 16 Personality Characteristics

    Institute of Scientific and Technical Information of China (English)

    吴幼华; 沈慧丽; 苏俊义

    2014-01-01

    目的:探讨甲基苯丙胺(“冰毒”)滥用人员的人格特征。方法:使用卡特尔16项人格因素问卷(16PF),对194例冰毒滥用人员进行测查。结果:被调查者男性居多,为134例(69.07%)。平均年龄34.1a ± s7.5a。以初中文化程度为主,共149例(76.80%)。职业以无业者居多,为178例(91.75%)。滥用的毒品以冰毒为主,但该群体中还有部分人员滥用其他毒品,如海洛因,氯胺酮(“K 粉”)等。滥用冰毒人员在乐群性,聪慧性,恃强性,兴奋性,敢为性,敏感性,怀疑性,幻想性,世故性,忧虑性,独立性和紧张性等均显著低于中国常模,而有恒性和实验性则显著高于常模。男性滥用者在乐群性,敏感性,独立性和自律性等均显著低于女性滥用者。结论:冰毒滥用人员有其特异的人格特征,其人格明显偏离正常,男女之间存在差异。在对该人群进行脱毒治疗,管理教育,心理康复时,应充分考虑到其特异的人格特征,做到有的放矢,加强沟通和交流,做好健康教育和心理辅导,提高该群体对药物滥用的阈值,防止或减少吸毒行为的反复发生,降低复吸率。%Objective:To investigate methamphetamine(“ ice”)abuse personality traits personnel. Methods:Questionnaire Cattell 16 Personality Factor(16PF)on 194 cases of methamphetamine abuse testing personnel investigation. Results:Respondents males for 134 cases(69. 07% ). The average age 34. 1a ± s7. 5a. In junior high school education based,total 149 cases(76. 80% ). Career mostly with unemployed for 178 cases(91. 75% ). Drug abuse in methamphetamine-based,but there are some people in the population abuse other drugs,such as heroin,ketamine(“K powder”)and so on. Methamphetamine abuse in gregarious person, intelligence,aggressiveness

  8. Miocene climate as recorded on slope carbonates : examples from Malta (Central Mediterranean) and Northeastern Australia (Marion Plateau, ODP LEG 194)

    Science.gov (United States)

    John, Cédric Michaël

    2003-08-01

    This study investigated the slope carbonates of two Miocene carbonate systems: the Maltese Islands (in the Central Mediterranean) and the Marion Plateau (Northeastern Australia, drilled during ODP Leg 194). The aim of the study was to trace the impact of the Miocene cooling steps (events Mi1-Mi6) in these carbonate systems, especially the Mi3 event, which took place around 13.6 Ma and deeply impacted the marine oxygen isotope record. This event also profoundly impacted oceanographic and climatic patterns, eventually leading to the establishment of the modern ice-house world. In particular, East Antarctica became ice covered at that period. The rational behind the present study was to investigate the impact that this event had on shallow water systems in order to complement the deep-sea record and hence acquire a more global perspective on Miocene climate change. The Maltese Islands were investigated for trends in bulk-rock carbon and oxygen isotopes, as well as bulk-rock mineralogy, clay minerals analysis and organic geochemisty. Results showed that the mid Miocene cooling event deeply impacted sedimentation at that location by changing sedimentation from carbonate to clay-rich sediments. Moreover, it was discovered that each phase of Antarctic glaciation, not just the major mid Miocene event, resulted in higher terrigenous input on Malta. Mass accumulation rates revealed that this was linked to increased runoff during periods when Antarctica was glaciated, and thus that the carbonate sediments were “diluted” by clay-rich sediments. The model subsequently developed to explain this implies feedback from Antarctic glaciations creating cold, dense air masses that push the ITCZ Northward, thus increasing precipitation on the North African subcontinent. Increased precipitation (or stronger African monsoon) accelerated continental weathering and runoff, thus bringing more terrigenous sediment to the paleo-location of the slope sediments of Malta. Spectral analysis of

  9. Detection of moisture and moisture related phenomena from Skylab. [correlation of S-194 antenna temperature and soil moisture content measurements for Kansas and Texas

    Science.gov (United States)

    Eagleman, J. R.; Pogge, E. C.; Moore, R. K. (Principal Investigator); Hardy, N.; Lin, W.; League, L.

    1973-01-01

    The author has identified the following significant results. Correlations between the S-194 antenna temperature and soil moisture have been obtained for three sets of data; one for Skylab 2 and two for Skylab 3. The best correlations were obtained for the surface to one inch depth in two cases and for the surface to two inches for the third case. Correlation coefficients for the surface to one inch depth were -0.98, -0.95, and -0.82. The lowest correlation coefficient was obtained with total soil moisture variations less than 4% across the test site.

  10. c.194 A>C (Q65P) mutation in the LMX1B gene in patients with nail-patella syndrome associated with glaucoma

    Science.gov (United States)

    Romero, Pablo; Sanhueza, Felipe; Lopez, Pamela; Reyes, Loreto

    2011-01-01

    Purpose To report the clinical, ophthalmic, extraophthalmic, and genetic characteristics of nail-patella syndrome (NPS) in a Chilean family and to investigate the expressivity of open angle glaucoma (OAG) and ocular hypertension (OHT) in the family members. Methods Five family members affected with NPS and two unaffected members underwent a complete ophthalmologic examination, including computerized visual field, optical coherence tomography (OCT) of the optic disc and ultrasound pachymetry. Renal function was assessed by urinalysis and blood tests. Orthopedic evaluations were also performed, including radiological studies of the wrist, elbow and hip joints. Genomic DNA was extracted from peripheral leukocytes of the five affected and two unaffected family members. Exons 2–6 of the LIM homeobox transcription factor 1-beta (LMX1B) gene were screened for mutations by DNA sequencing of the proband. We also screened for mutations in exon 2 by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) of the other participants and 91 blood donors. Results Five living family members from three generations were positively diagnosed with NPS, three of them with varying degrees of OAG and one with OHT. Retinal nerve fiber layer (RNFL) thickness measured by spectral domain OCT was below normal values in three individuals. All subjects evaluated had normal nephrologic function. Orthopedic, clinical, and radiological alterations were compatible with NPS. Screening for mutations in exons 2- 6 of LMX1B showed a heterozygous missense mutation c.194 A>C changing glutamine to proline within exon 2 in codon 65 (Q65P) of the coding sequence. This mutation was present in all NPS subjects and absent in the unaffected family members and in 91 Chilean blood donors. Conclusions This is the first report of c.194 A>C mutation in LMX1B in a Chilean family with NPS and the second worldwide. The phenotype associated with this mutation is variable within the family

  11. Description of E4 Transitions in A = 192, 194,196, 198 Platinum Isotopes in a Microscopic sdgIBM- 1

    Institute of Scientific and Technical Information of China (English)

    ZHANG ZhanJun; YANG Jie; WANG Xin; LIU Yong

    2001-01-01

    Influence of the effective fermion hexadecapole force newly incorporated in a microscopic sdgIBM-1 on spectra, reduced E2 and E4 transition matrix elements (T(E2)s and T(E4)s) in the even-even platinum isotopes (A = 192,194,196,198) is investigated in terms of numerical calculations. It is found that the introduced interaction causes only limited modification to the spectrum and T(E2)s, apart from a few exceptions. However, it plays an essential role in describing E4 transitions. Thus in the case that the interaction is incorporated with certain strength, a reasonable description of all the E4 transitions in the platinum isotopes is reached in the microscopic sdgIBM-1 in comparing both to experimental data and the results calculated in phenomenological boson model.``

  12. Evidenced Formal Coverage Index and universal healthcare enactment: A prospective longitudinal study of economic, social, and political predictors of 194 countries.

    Science.gov (United States)

    Feigl, Andrea B; Ding, Eric L

    2013-11-01

    Determinants of universal healthcare (UHC) are poorly empirically understood. We undertook a comprehensive study of UHC development using a novel Evidenced Formal Coverage (EFC) index that combines three key UHC elements: legal framework, population coverage, and accessibility. Applying the EFC index measures (legislation, ≥90% skilled birth attendance, ≥85% formal coverage) to 194 countries, aggregating time-varying data from 1880-2008, this study investigates which macro-economic, political, and social indicators are major longitudinal predictors of developing EFC globally, and in middle-income countries. Overall, 75 of 194 countries implemented legal-text UHC legislation, of which 51 achieved EFC. In a country-year prospective longitudinal analysis of EFC prediction, higher GDP-per-capita (per GDP-per-capita doubling, relative risk [RR]=1.77, 95% CI: 1.49-2.10), higher primary school completion (per +20% completion, RR=2.30, 1.65-3.21), and higher adult literacy were significantly associated with achieving EFC. Results also identify a GDP-per-capita of I$5000 as a minimum level for development of EFC. GDP-per-capita and education were each robust predictors in middle-income countries, and education remained significant even controlling for time-varying GDP growth. For income-inequality, the GINI coefficient was suggestive in its role in predicting EFC (p=0.024). For social and political indicators, a greater degree of ethnic fractionalization (per +25%, RR=0.51, 0.38-0.70), proportional electoral system (RR=2.80, 1.22-6.40), and dictatorships (RR=0.10, 0.05-0.27) were further associated with EFC. The novel EFC index and this longitudinal prospective study together indicate that investment in both economic growth and education should be seen of equal importance for development of UHC. Our findings help in understanding the social and political drivers of universal healthcare, especially for transitioning countries. PMID:23906506

  13. Photometric analysis of the structure evolution on the Pb-19.4%Sn melt surface in the S-L temperature range

    Directory of Open Access Journals (Sweden)

    Lyakhovitskii M.M.

    2011-05-01

    Full Text Available The structure evolution of alloys in solidification range is considered as the first-order phase transformation from the solid state to the liquid one, which occurs by the mechanism of nucleation and growth of more symmetrical phase to less symmetrical crystalline phase. The kinetic regularities of this transformation are studied by the method of the photometric analysis of structure images (PHASI, which makes it possible to establish the temperature dependence of the relationship between the solid and liquid phases and their distribution on the melt surface. The PHASI method is based on the combined analysis of the brightness spectra of the visible light reflections from the sample surface and of the distribution of its scattering centers in different intensity intervals. The data on the structure evolution of the Sn+19.4%Pb alloy upon melting and solidification were considered in parallel with the measured spectra of sound signals. It was revealed that a distinct maximum is observed in the temperature dependence of radiation energy in the temperature range of phase transformation from the liquid into the solid state and hot crack formation occurs near the transition zone in the region of the contact of the ingot with the crucible.

  14. Low temperature sintering and color of a new compound Sn 1.24Ti 1.94O 3.66(OH) 1.50F 1.42

    Science.gov (United States)

    Xie, Yahong; Yin, Shu; Yamane, Hisanori; Hashimoto, Takatoshi; Sato, Tsugio

    2009-09-01

    Nanopowder of a new tin(II) titanium(IV) oxide hydroxide fluoride, Sn 1.24Ti 1.94O 3.66(OH) 1.50F 1.42 with the pyrochlore-type structure (cubic a = 10.3777(7) Å, space group Fd-3 m) was prepared by using a microwave-assisted solvothermal reaction. The grain size of the nanopowder was 20-30 nm in diameter. Sn 1.24Ti 1.94O 3.66(OH) 1.50F 1.42 decomposed above 300 °C, but could be sintered to relative density greater than 99% by a hydrothermal hot-pressing (HHP) method at 270 °C and 80 MPa for 4 h. The synthesized powder and solidified body obtained using HHP showed significantly different color, probably due to the difference in water content.

  15. Ranchero Armature Test LA-19.4-CT-3: PBX-9501 Explosive with no smoothing layer. Firing point 88, 9/16/13

    Energy Technology Data Exchange (ETDEWEB)

    Glover, Brian B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Goforth, James H. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rae, Philip John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Dickson, Peter [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Briggs, Matthew E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Marr-Lyon, Mark [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hare, Steven John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Herrera, Dennis Harold [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Watt, Robert Gregory [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rousculp, Christopher L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-13

    LA-19.4-CT-3 (CT-3) was the third camera test in a series beginning in 1/11, which diagnose the performance of 6 mm thick, 6061 T-0 Al Ranchero armatures. [The test LA-43-CT-2 (CT-2) is described in LA-UR-14-21983.] The goal of CT-3 was to verify that PBX-9501, with 18 mm point spacing and no smoothing layer, could be used for Ranchero generator armatures in place of PBXN-110, which had been used in all previous Ranchero applications. CT-1 and CT-2 both had 43 cm long slapper detonator systems imbedded in the cast PBXN-110 explosive, but manufacturing a charge for a similar 9501 test was not cost effective. Instead, a single cylinder of 9501, 19.368 cm long and 15.494 cm (6.100”)in diameter, had a groove machined to accommodate a row of 11 SE-1 detonators with 18 mm point spacing along the mid-plane of the cylinder. The expansion of the armature looks like a slapper assembly along almost ½ of the circumference, and provides adequate proof of concept. Removing the smoother from PBXN-110-driven armatures increased the armature velocity from 3.1 mm/μs to 3.3 mm/μs, as seen in CT-2, and the velocity measured on CT-3 increased to 3.8 mm/μs. In addition, the camera records show that the surface of the armature is smooth enough, and free from ruptures for an expansion of greater that 2X. The advantage of using 9501 is that it precludes concerns about blow-outs seen when bubbles are left in the cast material, and gives extra velocity. The disadvantage is that the machined explosives are more expensive.

  16. The composition and distribution of metal clusters in the MoFe protein from a nifZ deletion strain (DJ 194) of Azotobacter vinelandii

    Institute of Scientific and Technical Information of China (English)

    ZHOU Huina; ZHANG Chunxi; ZHAO Ying; BIAN Shaomin; REN Fei; WANG Huangping; HUANG Jufu

    2005-01-01

    Through the anaerobic chromatography on the columns of DEAE 52, Q-Sepharose and Sephacryl S-200, a nitrogenase MoFe protein (ΔnifZ Av1) was obtained from a nifZ deleted mutant of Azotobacter vinelandii (stain DJ194). The results of Western blotting after anoxic native electrophoresis and SDS-PAGE showed that ΔnifZ Av1 was similar to wild type MoFe protein (OP Av1) at the electrophoretic mobility, molecular weight and subunit composition. Furthermore, ΔnifZ Av1 was also similar to OP Av1 at the molybdenum content, EPR signal (g≈4.3, 3.65 and 2.01), and the molar extinction coefficient (Δε) of circular dichroism (CD) at 660 nm region. All of these indicated that, besides having the same α2β2 composition as OP Av1, the ΔnifZ Av1 also contained equal amount of reductive FeMoco in the spin state of S=3/2 to OP Av1. However, the iron content and substrate (C2H2, H+ and N2)-reduction activity of ΔnifZ Av1 were 74% and 46%―50% of those of OP Av1, respectively. Furthermore, the Δε at around 450 nm, which reflects P-cluster in Av1, was obviously lower than that of OP Av1. It suggested that the difference between ΔnifZ Av1 and OP Av1 resulted from P-cluster rather than FeMoco, and from the half number of P-cluster in ΔnifZ Av1, but the composition or redox state of P-cluster in ΔnifZ Av1 were not changed. Thus it could propose that ΔnifZ Av1 is composed of two different αβ subunit pairs. One is a FeMoco- and P-cluster-containing pair, and the other is a P-cluster-deficient but FeMoco-con- taining pair. Since the deletion of nifZ gene leads to the deficiency of only one of two P-clusters in a α2β2 tetramer, the assembly of P-cluster may not simply depend on one gene product, and so a possible mechanism of NifZ is supposed here.

  17. 马流感病毒(A/equine/Qinghai/1/94)核蛋白基因的序列测定及同源性分析%Sequencing and Homology Analysis of the NP Gene of Equine Influenza Virus(A/equine/Qinghai/1/94)

    Institute of Scientific and Technical Information of China (English)

    杨建德; 薛飞; 王晓钧; 朱远茂; 赵立平; 吕晓玲; 沈荣显; 相文华; 李景鹏

    2003-01-01

    根据已发表的马流感病毒核蛋白基因序列,设计并合成一对特异性引物,经反转录-聚合酶链反应(RT-PCR)成功扩增出了我国马流感病毒(A/Equine/Qinghai/1/94)核蛋白基因,将该片段连接到PGEM-T-EASY载体并转化DH5α,提取阳性菌落的质粒经EcRo1酶切和PCR鉴定其大小为1.5kb左右,对其测序并进行分析发现,与A/Equine/Kentucky/2/86、A/Equine/Miami/1/63等关系较近,同源率为93.3%~.97.4%,而与我国马流感吉林A/Equine/Jilin/1/89株关系较远,同源率仅为84.6%.

  18. Molecular cloning and homology analysis of the NA gene of equine influenza virus( A/Equine/Qinghai/1/94)in China%马流感病毒(A/Equine/Qinghai/1/94)神经氨酸酶基因的克隆与同源性分析

    Institute of Scientific and Technical Information of China (English)

    杨建德; 王文军; 薛飞; 王晓钧; 朱远茂; 赵立平; 吕晓玲; 沈荣显; 许景军; 相文华

    2003-01-01

    本试验根据已发表的马流感病毒神经氨酸酶(NA)基因序列,设计并合成一对特异性引物,经反转录-聚合酶链反应(RT-PCR)成功扩增出了我国马流感病毒青海株(A/Equine/Qnghai/1/94)NA基因,将片段连接到PGEM-T-easy载体并转化DH5α,提取阳性菌落的质粒经EcRo1酶切和PCR鉴定其大小均为1.4Kb左右,对其测序并构建NA基因进化树.经过比较分析发现,我国马流感病毒青海株与A/Equine/Alaska/1/91、A/Equine/Tennessee/5/86和A/Equine/Algiers/72等关系较近,核苷酸同源率为98.2%~97.4%;与我国马流感吉林株(A/Equine/Jilin/1/89)关系较远,核苷酸同源率仅为72.0%;而与H7N7亚型马流感病毒A/Equine/Prague/1/56核苷酸同源率仅为38.0%.

  19. Identification of Two Novel Anti-Fibrotic Benzopyran Compounds Produced by Engineered Strains Derived from Streptomyces xiamenensis M1-94P that Originated from Deep-Sea Sediments

    Directory of Open Access Journals (Sweden)

    Lei Feng

    2013-10-01

    Full Text Available The benzopyran compound obtained by cultivating a mangrove-derived strain, Streptomyces xiamenensis strain 318, shows multiple biological effects, including anti-fibrotic and anti-hypertrophic scar properties. To increase the diversity in the structures of the available benzopyrans, by means of biosynthesis, the strain was screened for spontaneous rifampicin resistance (Rif, and a mutated rpsL gene to confer streptomycin resistance (Str, was introduced into the S. xiamenensis strain M1-94P that originated from deep-sea sediments. Two new benzopyran derivatives, named xiamenmycin C (1 and D (2, were isolated from the crude extracts of a selected Str-Rif double mutant (M6 of M1-94P. The structures of 1 and 2 were identified by analyzing extensive spectroscopic data. Compounds 1 and 2 both inhibit the proliferation of human lung fibroblasts (WI26, and 1 exhibits better anti-fibrotic activity than xiamenmycin. Our study presents the novel bioactive compounds isolated from S. xiamenensis mutant strain M6 constructed by ribosome engineering, which could be a useful approach in the discovery of new anti-fibrotic compounds.

  20. $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with radioactive At beams

    CERN Multimedia

    We propose to study the $\\beta$-delayed fission, laser spectroscopy and radioactive decay of the newly available pure beams of neutron-deficient and neutron-rich astatine (Z=85) isotopes. The fission probability and the fission fragment distribution of the even-even isotopes $^{194,196}$Po following the $\\beta$-decay of the isotopes $^{194,196}$At will be studied with the Windmill setup. In-source laser spectroscopy will be performed on the entire astatine isotopic chain, using a combination of the Windmill setup, ISOLTRAP MR-ToF and ISOLDE Faraday. Radioactive decay data will be acquired at the Windmill setup throughout those studies and contribute to the global understanding of the phenomenon of shape coexistence in the neutron-deficient lead region.

  1. Insights into the Hydrocarbon Tolerance of Two Devosia Isolates, D. chinhatensis Strain IPL18T and D. geojensis Strain BD-c194T, via Whole-Genome Sequence Analysis.

    Science.gov (United States)

    Hassan, Yousef I; Lepp, Dion; Li, Xiu-Zhen; Zhou, Ting

    2015-01-01

    Hexachlorocyclohexane (HCH) was among the most commonly used pesticides after the Second World War. The extensive use of this hydrocarbon for almost six decades has created a contamination problem on a global scale, and bioremediation methods are being extensively explored. The reported ability of some Devosia species to grow in the presence of appreciable amounts of hydrocarbons (2,000 mg/kg of contaminated soil) is attracting closer attention. Here, we report the de novo genome assembly of two hydrocarbon-tolerating Devosia isolates, D. chinhatensis strain IPL18(T) and D. geojensis strain BD-c194(T), as a first step toward understanding the metabolic pathways involved in their environmental adaptation and tolerance toward hydrocarbons. PMID:26251505

  2. „Neue Leitbilder für den Fortschritt“ (LS 194. Ein Plädoyer für die Wiederentdeckung praktischer Weisheit als neues Leitbild in der Marktwirtschaft

    Directory of Open Access Journals (Sweden)

    Claudius Bachmann

    2016-07-01

    Full Text Available In the light of the far-reaching leadership failures and business scandals of the last decades, the question has often been raised of whether we are reaping the results of the practical application of abstract management theory which is actually counteracting a socially, environmentally, and economically sustainable market economy. In this sense, Pope Francis recently called for ‘new models of progress’ to reflect on ‘the meaning of the economy and its goals’ (LS 194. To answer these calls, I first provide an overview of the recent discourse in leadership and organizational studies that have critically scrutinized the established theories and models of mainstream business. Second, I draw on the Apostolic Exhortation Evangelii Gaudium and the Encyclical Laudato Si’ to derive the cornerstones of an ‘evangelizing approach’ to the guiding principles of management theory and practice suggested by Pope Francis. Third, to facilitate this renewal, I introduce the ancient idea of practical wisdom (prudence which has recently enjoyed a remarkable renaissance in the literature and is considered as a new transformative paradigm for management theory and practice.

  3. 40 CFR 194.26 - Expert judgment.

    Science.gov (United States)

    2010-07-01

    ... CFR PART 191 DISPOSAL REGULATIONS Compliance Certification and Re-certification General Requirements...: (i) Individuals who are members of the team of investigators requesting the judgment or the team of... organizational level, a supervisory role or who are supervised by those who will utilize the judgment were...

  4. 26 CFR 1.194-3 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... used in forestation or reforestation. The property must be held by the taxpayer for the growing and... qualifying reforestation expenditures incurred by such taxpayer on leased qualified timber property... which is attributable to reforestation expenditures. (c) Reforestation expenditures—(1) In general....

  5. Synthesis and electrochemical characterizations of spinel LiMn1.94MO4 (M = Mn0.06, Mg0.06, Si0.06, (Mg0.03Si0.03)) compounds as cathode materials for lithium-ion batteries

    Science.gov (United States)

    Zhao, Hongyuan; Liu, Xingquan; Cheng, Cai; Li, Qiang; Zhang, Zheng; Wu, Yue; Chen, Bing; Xiong, Weiqiang

    2015-05-01

    The spinel LiMn1.94MO4 (M = Mn0.06, Mg0.06, Si0.06, (Mg0.03Si0.03)) compounds are successfully synthesized by citric acid-assisted sol-gel method. The crystal structures and morphologies of synthesized compounds are characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), respectively. All the compounds possess the cubic spinel structure of LiMn2O4 with space group of Fd-3m. The electrochemical properties of synthesized compounds are investigated by galvanostatic charge-discharge test, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The results show that the Si-doping can increase the discharge capacity of LiMn2O4 due to the more expanded and regular MnO6 octahedra. In particular, for the LiMn1.94Mg0.03Si0.03O4 compound, the addition of Si4+ ions can make up for the shortage of Mg-doping in term of the discharge capacity. As a result, the Mg2+ and Si4+ co-doping has the effect of synergistic enhancement, which can make full use of the respective advantages of Mg-doping and Si-doping. The optimal LiMn1.94Mg0.03Si0.03O4 can deliver the initial discharge capacity of 128.3 mAh g-1 with good capacity retention of 92.8% after 100 cycles at 0.5 C in the voltage range of 3.20-4.35 V. Compared with the undoped LiMn2O4, the co-doped compound also presents superior rate performance, especially the capacity recovery performance.

  6. Evaluation of a Wet Chemistry Method for Isolation of Cyclotron Produced [211At]Astatine

    Directory of Open Access Journals (Sweden)

    Shigeki Watanabe

    2013-09-01

    Full Text Available A “wet chemistry” approach for isolation of 211At from an irradiated bismuth target is described. The approach involves five steps: (1 dissolution of bismuth target in conc. HNO3; (2 removal of the HNO3 by distillation; (3 dissolution of residue in 8 M HCl; (4 extraction of 211At from 8 M HCl into DIPE; and (5 extraction of 211At from DIPE into NaOH. Results from 55 “optimized” 211At isolation runs gave recovery yields of approximately 78% after decay and attenuation corrections. An attenuation-corrected average of 26 ± 3 mCi in the target provided isolated (actual yields of 16 ± 3 mCi of 211At. A sixth step, used for purification of 211At from trace metals, was evaluated in seven runs. In those runs, isolated 211At was distilled under reductive conditions to provide an average 71 ± 8% recovery. RadioHPLC analyses of the isolated 211At solutions, both initial and after distillation, were obtained to examine the 211At species present. The primary species of 211At present was astatide, but astatate and unidentified species were also observed. Studies to determine the effect of bismuth attenuation on 211At were conducted to estimate an attenuation factor (~1.33 for adjustment of 211At readings in the bismuth target.

  7. Production of Astatine-211 at the Duke University Medical Center for its regional distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, Michael [Duke University Medical Center, Durham, NC (United States)

    2016-01-01

    Systemic targeted radiation therapy and radioimmunotherapy continue to be important tools in the treatment of certain cancers. Because of their high energy and short path length, alpha particle emitters such as 211At are more effective than either external beam x- ray or in vivo beta radiation in delivering potentially curative doses of radiation. The limited clinical trials that have been conducted to date have yielded encouraging responses in some patients, e.g., malignant brain tumors. In order to escalate the additional necessary research and development in radiochemistry, radiobiology and efficacy evaluation of alpha particle radiotherapeutics, it is universally agreed that access to an affordable, reliable supply of 211At is warranted. In conjunction with the Department of Energy's intent to enhance stable and radioactive isotope availability for research applications, it is the primary objective of this project to improve 211At production and purification capabilities at Duke so that this radionuclide can be supplied to researchers at other institutions throughout the US.The most widely used 211At production method involves the α,2n reaction on Bismuth using a cyclotron with beams ≤ 28 MeV. Yields can be enhanced with use of an internal target that allows for a higher alpha fluence plus efficient heat dissipation in the target. Both of these items are in place at Duke; however, in order to support production for multi-institutional use, irradiation campaigns in excess of 50 µAp and four hours duration will be needed. Further, post-irradiation processing equipment is lacking that will enable the distribution process. Financial support is sought for i) a shielded, ventilated processing/containment hood; ii) development of a post-irradiation target retrieval system; iii) fabrication of a 211At distillation and recovery module and iv) a performance review and, where needed, an enhancement of seven major subsystems that comprise the CS-30 Cyclotron. With these modifications in place, routine production of ≥200 mCi of At-211 should be readily achievable, given our methodological development of At-211 target preparation, internal target irradiation and dry distillation to recover the radionuclide.

  8. Final Report for grant entitled "Production of Astatine-211 for U.S. Investigators"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott

    2012-12-12

    Alpha-particle emitting radionuclides hold great promise in the therapy of cancer, but few alpha-emitters are available to investigators to evaluate. Of the alpha-emitters that have properties amenable for use in humans, 211At is of particular interest as it does not have alpha-emitting daughter radionuclides. Thus, there is a high interest in having a source of 211At for sale to investigators in the US. Production of 211At is accomplished on a cyclotron using an alpha-particle beam irradiation of bismuth metal. Unfortunately, there are few cyclotrons available that can produce an alpha particle beam for that production. The University of Washington has a cyclotron, one of three in the U.S., that is currently producing 211At. In the proposed studies, the things necessary for production and shipment of 211At to other investigators will be put into place at UW. Of major importance is the efficient production and isolation of 211At in a form that can be readily used by other investigators. In the studies, production of 211At on the UW cyclotron will be optimized by determining the best beam energy and the highest beam current to maximize 211At production. As it would be very difficult for most investigators to isolate the 211At from the irradiated target, the 211At-isolation process will be optimized and automated to more safely and efficiently obtain the 211At for shipment. Additional tasks to make the 211At available for distribution include obtaining appropriate shipping vials and containers, putting into place the requisite standard operating procedures for Radiation Safety compliance at the levels of 211At activity to be produced / shipped, and working with the Department of Energy, Isotope Development and Production for Research and Applications Program, to take orders, make shipments and be reimbursed for costs of production and shipment.

  9. Dicty_cDB: CHO194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available er of HSP's gapped (non-prelim): 0 length of query: 121 length of database: 80,480,566 effective HSP length: 17 effective... length of query: 104 effective length of database: 78,821,179 effective search space: 8197402616 effective...successful extensions: 0 Number of sequences better than 10.0: 0 length of query: 121 length of database: _,504,085,797 effective... HSP length: 21 effective length of query: 100 effective length of database: ^,543,142,933 effective... search space: 4654314293300 effective search space used: 4654314293300 T: 0 A: 0 X1: 6 (11.9 b

  10. 46 CFR 194.10-5 - Type and location.

    Science.gov (United States)

    2010-10-01

    ... utilized shall not be used for stowage of other hazardous materials covered by 49 CFR parts 171-179. The... requirements of 49 CFR part 176. (c) Magazine chests. (1) Magazine chests shall be located on the weather decks... in bearing with a bulkhead forming the boilerroom, engineroom, gallery, or other high fire...

  11. 26 CFR 1.194-2 - Amount of deduction allowable.

    Science.gov (United States)

    2010-04-01

    ... deduction allowable. (a) General rule. The allowable monthly deduction with respect to reforestation expenditures made in a taxable year is determined by dividing the amount of reforestation expenditures made in... subject to election. A taxpayer may elect to amortize up to $10,000 of qualifying...

  12. Dicty_cDB: CFC194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available equences producing significant alignments: (bits) Value N AF305060 |AF305060.1 Dictyostelium discoideum Wiscott...nts: (bits) Value AF305060_1( AF305060 |pid:none) Dictyostelium discoideum Wiscott

  13. Dicty_cDB: AFF194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available gsncitkttrktktdgirdskrirkissrrsrc*rkyr l*s*rkektrri*kenagktk*skrcsktknt*r*rkrkn*irktkrkrstkrinetsne wck*w*it...All Frames) Frame A: ttttnrgdnittnik***i*ktgsncitkttrktktdgirdskrirkissrrsrc*rkyr l*s*rkektrri*kenagktk*skrcskt

  14. 27 CFR 26.194 - Detention of articles.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Detention of articles. 26..., DEPARTMENT OF THE TREASURY LIQUORS LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Shipment of... Detention of articles. (a) Upon receiving a notification in accordance with § 26.193(b), the appropriate...

  15. Dicty_cDB: SLD194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Dictyostelium discoideum gamete cDNA clone:FCL-AC... 161 7e-36 1 ( AU285021 ) Dictyostelium discoideum gamete... cDNA clone:FCL-AA... 161 7e-36 1 ( AU285015 ) Dictyostelium discoideum gamete ...cDNA clone:FCL-AA... 161 7e-36 1 ( AU284890 ) Dictyostelium discoideum gamete cDNA clone:FC-BO1... 161 7e-36... 1 ( AU284628 ) Dictyostelium discoideum gamete cDNA clone:FC-BF1... 161 7e-36 1 ( AU284420 ) Dictyostelium discoideum gamete... cDNA clone:FC-AT2... 161 7e-36 1 ( AU284396 ) Dictyostelium discoideum gamete cDNA clone:F

  16. 40 CFR 194.23 - Models and computer codes.

    Science.gov (United States)

    2010-07-01

    ... executing the computer codes, including hardware and software requirements, input and output formats with explanations of each input and output variable and parameter (e.g., parameter name and units); listings of input and output files from a sample computer run; and reports on code verification,...

  17. Dicty_cDB: SFE194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available .26 Human DNA sequence *** SEQUENCING IN PROGRESS *** from clone RP11-368H14. 363 0.0 15 AF419983 |AF419983.1 Closterium calo...sporum var. calosporum 26S ribosomal RNA gene, partial sequence. 406 0.0 9 AF419986 |AF4199...genic spacer, partial sequence. 406 0.0 9 AF419996 |AF419996.1 Closterium calosporum var. himalayense 26S ri

  18. 46 CFR 194.10-20 - Magazine chest construction.

    Science.gov (United States)

    2010-10-01

    .... Side shields shall be offset from the body a distance of 1 inch. The top shield shall be offset a distance of 11/2 inches. Sun shields may be omitted when chests are installed “on deck protected,” shielded... lid shall have a minimum thickness of 1/8 inch. (b) Permanent sun shields shall be provided for...

  19. Dicty_cDB: SFF194 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 124-6045772 strain AX4, complete sequence. 34 0.50 7 BE317387 |BE317387.2 NF068C10LF1F1070 Developing leaf M...249770 |BE249770.2 NF022C10LF1F1081 Developing leaf Medicago truncatula cDNA clone NF022C10LF 5', mRNA seque

  20. 云南省1194名接受HAART的艾滋病病人的生命质量测评及影响因素分析%Quality of life and related factors among 1 194 AIDS patients receiving HAART in Yunnan province

    Institute of Scientific and Technical Information of China (English)

    王晓锋; 王启林; 杨霞

    2011-01-01

    目的 探讨接受高效抗反转录病毒治疗(HAART)的艾滋病病人的生命质量及其影响因素.方法 采取典型抽样的方法,使用中文版SF 36量表和自编基本情况调查表,对研究对象进行横断面调查,应用Epi Data 3.1建立数据库,SPSS 12.0进行统计分析.结果 选择1个省级、2个州级、5个县级抗病毒治疗医院作为研究现场,选择在2009年4月以前在8个研究现场入组并接受抗病毒治疗的艾滋病病人作为研究对象.①1 194名调查对象,SF 36量表8个领域百分转换得分中,躯体功能(PF)得分最高(86.00±18.48),总健康(GH)得分最低(44.37±21.59),领域间得分差异有统计学意义(P<0.01).②女性病人的GH、肌体疼痛(BP)维度得分高于男性病人(P<0.05);不同年龄的病人在PF、GH 2个领域的得分差异有统计学意义(P<0.05),年龄小的病人PF、GH得分高于年龄大的病人;不同文化程度的病人的PF、生命力(VT)、情感角色(RE)、心理健康(MH)、BP得分差异有统计学意义(P<0.05),文化程度低的病人以上领域得分低于文化程度高的病人;不同婚姻状况的病人生命质量8个领域得分差异均有统计学意义(P<0.05),已婚病人生命质量好于未婚和离异/独居/分居病人;农村户籍的调查对象的PF、GH、社会功能(SF)3个维度得分明显高于城镇户籍的调查对象(P<0.05);不同职业的病人生命质量8个领域得分差异均有统计学意义(P<0.05),公职人员、个体从业人员的生命质量好于无业人员和农民.结论 性别、年龄、文化程度、婚姻状况、户籍、职业是影响高效抗反转录病毒治疗艾滋病病人生命质量的因素.%Objective To investigate the quality of life and related factors among AIDS patients receiving highly active antiretroviral therapy(H AART) . Methods One provincial-level , two prefecture-level and five county-level HAART hospitals were selected as research sites by

  1. KN194L05: WHOI cruise 194 leg 05 aboard the R/V Knorr from 2008-11-01 - 2008-11-14 (NODC Accession 0080960)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  2. An all-solid state laser system for the laser ion source RILIS and in-source laser spectroscopy of astatine at ISOLDE,CERN

    OpenAIRE

    Rothe, Sebastian

    2012-01-01

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spec...

  3. People and things. CERN Courier, Jun 1979, v. 19(4)

    International Nuclear Information System (INIS)

    On 1 April, six months ahead of schedule, electrons were injected into the 8 GeV electron-positron storage ring, CESR, at Cornell. Two weeks later beam was accumulated at an energy of 5.5 GeV. The contract for the management and construct/on of the conventional facilities of the ISABELLE 400 GeV proton storage rings to be built at the Brookhaven Laboratory has been awarded to the New York firm of Ammann and Whitney. Greatly helped by the quality of the beams from the new linac, the CERN 800 MeV four-ring Booster has achieved several new records which bode well for the role it has to play with the PS in feeding the high energy machines in the coming years

  4. 41 CFR 102-194.25 - What is an automated Standard or Optional format?

    Science.gov (United States)

    2010-07-01

    ... Optional format? An automated Standard or Optional format is an electronic version of the officially prescribed form containing the same data elements and used for the electronic transaction of information...

  5. LSW-177 and LSW-194: Red-fleshed watermelon lines with low-total soluble solids

    Science.gov (United States)

    Increasing fruit total soluble solids (TSS) content has been a priority of many breeding programs, and the TSS content of modern watermelon [Citrullus lanatus var. lanatus (Thunb.) Matsum. & Nakai)] cultivars is considerably higher than their heirloom counterparts (12-14% TSS compared to ~10% TSS re...

  6. 40 CFR 267.194 - What installation requirements must I follow?

    Science.gov (United States)

    2010-07-01

    ... must support and protect ancillary equipment against physical damage and excessive stress due to settlement, vibration, expansion, or contraction. (b) You must provide the type and degree of corrosion... required in 40 CFR 270.11(d)....

  7. Yucca Mountain Site Characterization Project Bibliography, July, December 194: An update

    International Nuclear Information System (INIS)

    Following a reorganization of the Office of Civilian Radioactive Waste Management in 1990, the Yucca Mountain Project was renamed Yucca Mountain Site Charactrization Project. The title of this bibliography was also changed to Yucca Mountain Site Characterization Project Bibliography. Prior to August 5, 1988, this project was called the Nevada Nuclear Waste Storage Investigations. This bibliography contains information on this ongoing project that was added to the Department of Energy's Science and Technology Database from July 1, 1994 through December 31, 1994. The bibliography is categorized by principal project participating organization. Participant-sponsored subcontractor reports, papers, and articles are included in the sponsoring organization's list. Another section contains information about publications on the Energy Science and Technology Database that were not sponsored by the project but have some relevance to it

  8. Susceptibility of 194 Salmonella Isolates to 17 Chemicals used as Sanitizers and Biocides

    Science.gov (United States)

    Salmonella is a major cause of foodborne illnesses in the United States. Meat processing facilities use a wide variety of antimicrobial interventions to reduce Salmonella contamination. The objective of this study was to determine the minimum inhibitory concentration (MIC) of sanitizers and biocides...

  9. 19 CFR 191.194 - Action on application to participate in compliance program.

    Science.gov (United States)

    2010-04-01

    ... the program participant of its right to file an appeal of the removal in accordance with paragraph (f... cases of willfulness on the part of the program participant or when required by public health, interest... and Programs, Office of International Trade, within 30 days after issuance of the applicable...

  10. JPL Physical Oceanography Distributed Active Archive Center (PO.DAAC) data availability, version 1-94

    Science.gov (United States)

    1994-01-01

    The Physical Oceanography Distributed Active Archive Center (PO.DAAC) archive at the Jet Propulsion Laboratory (JPL) includes satellite data sets for the ocean sciences and global-change research to facilitate multidisciplinary use of satellite ocean data. Parameters include sea-surface height, surface-wind vector, sea-surface temperature, atmospheric liquid water, and integrated water vapor. The JPL PO.DAAC is an element of the Earth Observing System Data and Information System (EOSDIS) and is the United States distribution site for Ocean Topography Experiment (TOPEX)/POSEIDON data and metadata.

  11. 19 CFR 19.4 - CBP and proprietor responsibility and supervision over warehouses.

    Science.gov (United States)

    2010-04-01

    ... transportation, receipts, deliveries, sampling, recordkeeping, repacking, manipulation, destruction, physical and...) Protect proprietary information in its custody from unauthorized disclosure. (ii) Availability. Records... quantity in each storage location, covered by any warehouse entry, general order, or seizure so a...

  12. Djurleite (Cu1.94S) and low chalcocite (Cu2S): New crystal structure studies

    Science.gov (United States)

    Evans, H.T., Jr.

    1979-01-01

    Additional x-ray structure studies on low chalcocite generally confirm the previously reported structure but show that either disorder is present or the true space group is not P21/c but Pc, four of the 96 copper atoms in the monoclinic unit cell taking on twofold (linear) coordination. The crystal structure of djurleite has been solved in space group P21/n, the monoclinic cell having parameters a = 26.897, b = 15.745, and c = 13.565 angstroms; ?? = 90.13??; and a content of 248 copper and 128 sulfur atoms. Of the 62 different copper atoms in the structure, 52 are in threefold, triangular coordination with sulfur, nine in tetrahedral, and one in linear coordination.

  13. 9 CFR 381.194 - Transportation and other transactions concerning dead, dying, disabled, or diseased poultry, and...

    Science.gov (United States)

    2010-01-01

    ... concerning dead, dying, disabled, or diseased poultry, and parts of carcasses of poultry that died otherwise... SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION...

  14. Analysis of ER and fission in decay of 210Rn* formed in 16O + 194Pt reaction

    International Nuclear Information System (INIS)

    In the present work, the decay of 210Rn* is studied using the dynamical cluster decay model (DCM). The ER as well as fission cross-sections are calculated by independent as well as simultaneous choice of neck length parameter 'ΔR'

  15. 77 FR 194 - Federal Acquisition Regulation; Time-and-Materials and Labor-Hour Contracts for Commercial Items

    Science.gov (United States)

    2012-01-03

    ... material; (4) Clarify contract types; (5) Potential for rule to limit the use of T&M contracts; (6...) The ordering activity shall specify the order type (i.e., firm-fixed price, time- and-materials, or... RIN 9000-AL74 Federal Acquisition Regulation; Time-and-Materials and Labor-Hour Contracts...

  16. The quasicontinuum of gamma rays from the feeding and decay of the superdeformed in {sup 194}Pb

    Energy Technology Data Exchange (ETDEWEB)

    Lauritsen, T.; Ahmad, I.; Carpenter, M.P. [and others

    1995-08-01

    Over the last year we developed techniques for the study of the quasicontinuum of gamma-rays from both the feeding and especially the decay of the superdeformed (SD) bands in the Hg nuclei, most notably {sup 192}Hg. From this analysis we could extract both the spin and energy of some of the SD bands. The quasicontinuum analysis is the only technique so far that could extract these two fundamental properties of the now more than 100 SD bands found in the A = 150 and A = 190 regions. We based our understanding of the feeding and decay on comparisons of the data with extensive Monte Carlo simulations of the emission of gamma rays, both from the entry distribution toward the SD minimum, and, at lower spins, from the decay out of the SD band back to the states in the normal well.

  17. 76 FR 194 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2011-01-03

    ... or corporate bonds, denominated in local currencies or U.S. dollars, as well as issues denominated in..., Malaysia, Philippines, Singapore, Thailand and Viet Nam) increased by 24.4% through June 2010. China's..., distributions and taxes is included in the Registration Statement. Availability of Information The Fund's...

  18. Compound list: simvastatin [Open TG-GATEs

    Lifescience Database Archive (English)

    Full Text Available simvastatin SST 00117 ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Human/in_vitro/simv...astatin.Human.in_vitro.Liver.zip ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Rat/in_vitro/simv...astatin.Rat.in_vitro.Liver.zip ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Rat/in_vivo/Liver/Single/simv...archive/open-tggates/LATEST/Rat/in_vivo/Liver/Repeat/simvastatin.Rat.in_vivo.Liver.Repeat.zip ...

  19. 22 CFR Appendix A to Part 194 - Inter-American Commercial Arbitration Commission Rules of Procedure (As Amended April 1, 2002)

    Science.gov (United States)

    2010-04-01

    .... 2Notice, Calculation of Periods of Time Art. 3Notice of Arbitration Art. 4Representation and Assistance... arbitration from which the parties cannot derogate, that provision shall prevail. Notice, Calculation of... shall determine the admissibility, relevance, materiality and weight of the evidence offered....

  20. Search for shape coexistence in {sup 188,190}Pb via fine structure in the alpha decay of {sup 192,194}Po

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, I.; Davids, C.; Janssens, R.V.F. [and others

    1995-08-01

    The interaction between coexisting shapes in nuclei near closed shells was of great interest in the past decade. Excited 0{sup +} states at low energy can often be identified as the bandheads of structures with differing shapes built on those states, These structures were identified in {sup 190-198}Pb via beta decay and alpha decay {open_quotes}fine structure{close_quotes} studies. Coexistence of different shapes in Pb nuclei was predicted by Nilsson-Strutinsky calculations, in which both the oblate and prolate minima were predicted to have excitation energies near 1 MeV. It was our intention to continue the systematic study of the Pb nuclides by searching for excited O{sup +} states in {sup 188}Pb by observing the fine structure in the alpha decay of {sup 192}Po.

  1. Spectral and timing properties of MAXI J1836-194 during its 2011 outburst and estimation of mass with TCAF solution

    Science.gov (United States)

    Jana, Arghajit; Debnath, Dipak; Chakrabarti, Sandip Kumar; Mondal, Santanu; Chatterjee, Debjit; Molla, Aslam Ali

    2016-07-01

    We make a detailed analysis of the BHC using 2.5-25 keV RXTE/PCA data with two components advective flow (TCAF) model generated fits file as an additive table model in XSPEC. From the spectral analysis, we extract Keplerian disk rate, sub-Keplerian halo rate, shock location and compression ratio. We also estimate mass of the BHC from spectral analysis and we find it in the range of 7.5-11 M_{Sun}. During the entire outburst we keep the normalization in a very narrow range of 0.25-0.35 except a few days when radio jet is observed. We find quasi periodic oscillation (QPO) frequencies are in sporadic nature. From the variation of accretion rate ratio (ARR=halo rate/disk rate), QPO frequencies and photon indices, we classify the outburst in two states - hard and hard-intermediate. Unlike other BHC, soft and soft-intermediate states are absent during the entire outburst. This may be the reason due to the fact that the BHC is immersed within the excreation disk of the companion which is a Be star.

  2. A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency

    OpenAIRE

    Bechtold-Dalla Pozza, Susanne; Hiedl, Stefan; Roeb, Julia; Lohse, Peter; Malik, Raleigh E.; Park, Soyoung; Duran-Prado, Mario; Rhodes, Simon J.

    2012-01-01

    Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD) who harbor a novel mutation in LHX3. Methods: Two female siblings from related parents were examined. Both patients had neonatal complications. The index patient had CPHD featuring deficiencies of GH, LH, FSH, PRL, and TSH, with later onset ...

  3. Hepatitis B virus in tenofovir-naive Chinese patients with chronic hepatitis B contains no mutation of rtA194T conferring a reduced tenofovir susceptibility

    Institute of Scientific and Technical Information of China (English)

    LIU Yan; WANG Chun-mei; CHENG Jun; LIANG Zhao-ling; ZHONG Yan-wei; REN Xiao-qiang; XU Zhi-hui; Fabien Zoulim; XU Dong-ping

    2009-01-01

    @@ Recently the Chinese Ministry of Health declared that 93 million people were chronically infected with hepatitis B virus (HBV) in China. Four nucleotide analogues (Nas) are currently approved for the treatment of HBV infection, I.e., lamivudine (LAM), adefovir (ADV), entecavir (ETV), and telbivudine (L-dT).1 In contrast to therapeutic benefits, prolonged use of Nas increases the emergence of drug-resistant mutations in the HBV reverse transcriptase (RT) domain, leading to a.

  4. Les ONG : instruments du néolibéralisme ou alternatives populaires ?. -Paris, l’harmattan, 1998- 194 p

    OpenAIRE

    Izerouken, Arab

    2013-01-01

    Les auteurs ayant collaboré à la réalisation de cette publication, annoncent d’emblée la couleur. Ils expriment, dans leurs analyses des ONG (en particulier les ONG dites " de développement"), le point de vue du Sud. L’ouvrage, à travers les différents articles qui le composent, passe au crible les intentions affichées, les pratiques, le fonctionnement et l’organisation des ONG. Les auteurs conscients de la difficulté qu’il y a à définir le groupe notionnel ONG" semblent, devant le succès du ...

  5. Effects of Simvastatin on Ion Channel Currents in Ventricular Myocytes from Acute Infarcted Heart of Normocholesterolemic Rabbits

    Institute of Scientific and Technical Information of China (English)

    Chao Ding; Xianghua Fu; Li Yang; Huixiao Chen; Junxia Li; Yuying Zhao; Jie Li; Jie Wang

    2008-01-01

    Objectives To investigate the effects of simvastatin on membrane ionic currents in left ventricular myocytes of rab-bit heart suffering from acute myocardial infarction (AMI), so as to explore the ionic mechanism of statin treatment for antiarrhythmia. Methods Forty-five New Zealand rabbits were randomly divided into three groups: AMI group, simv-astatin intervention group (Statin group) and sham-operated control group (CON). Rabbits were infarcted by ligation of the left anterior descending coronary artery after administration of oral simvastatin 5 mg · kg-1 · d-1 (Statin group) or placebo (AMI group) for 3 days. Single ventricular myocytes were isolated enzymatically from the epicardial zone of the infracted region 72 h later. Whole cell patch clamp technique was used to record membrane ionic currents, inclu-ding sodium current (Ina), L-type calcium current (Ica-L) and transient outward potassium current (Ito). Results ① There was not significant difference in serum cholesterol concentration among three groups. ② The peak Ina current den-sity (at -30 mV) was significantly decreased in AMI group (-25.26±5. 28, n = 13), comparing with CON (-42. 78±5.48, n = 16), P < 0. 05, while it was significantly increased in Statin group (-39. 83±5. 65 pA/pF, n = 12) comparing with AMI group, P <0. 01; The peak I Ca-L current density (at 0 mV) was significantly decreased in AMI group (- 3.43±0. 92 pA/pF, n = 13) comparing with CON (- 4. 56±1.01 pA/pF, n = 15), P < 0. 05, while it was significantly increased in Statin group (-4. 18±0. 96 pA/pF, n = 12) comparing with AMI group, P <0. 05; The Ito current density (at + 60 mV) was significantly decreased in AMI group (11.41±1.94 pA/pF, n = 13) compa-ring with CON (17. 41±3. 13 pA/pF, n = 15), P <0. 01, while it was significantly increased in Statin group (16. 11±2. 43 pA/pF, n = 14) comparing with AMI group, P < 0. 01. Conclusions AMI induces significant down-regula-tion of Ina, I Ca-L and Ito. Pretreatment with

  6. Dicty_cDB: Contig-U10506-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available = 9e-54 Identities = 194/194 (100%) Strand = Plus / Plus Query: 14 tccaaanaaaatccnanaaccatatttnttaatattnccaa...aatcgganatcatcnttnc 73 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 14 tccaaanaaaatccna...ct: 74 caatttnganaaaaccnttggnaaaacttggnttattgattttgaaaaanaaacaactaa 133 Query: 134 aatccnanatggnagnttcnttncn...||||||||||||||||||| Sbjct: 134 aatccnanatggnagnttcnttncnaatattnaaaanacnttnattcnttggaanagaca 193 Query: 194 n... Score = 206 bits (104), Expect(2) = 2e-60 Identities = 194/194 (100%) Strand = Plus / Minus Query: 14 tccaaanaaaatccna

  7. Le palais d’Aiétès et son jardin chez Apollonios de Rhodes (Arg., III, v. 194-252). Un exemple de paysage-palimpseste antique ? The Palace of Aeetes and its Garden in Apollonius of Rhodes (Arg., III, lines 194-252). An example of ancient landscape as palimpsest? Il palazzo di Eeta e il suo giardino in Apollonio Rodio (Arg., III, 194-252). Un esempio di paesaggio-palinsesto antico?

    OpenAIRE

    Laury-Nuria André

    2012-01-01

    Lorsque le lecteur découvre au chant III des Argonautiques d’Apollonios de Rhodes l’espace du « paysage urbain » colque, au fur et à mesure de la progression visuelle des personnages, se dessine mentalement tout un espace littéraire fait de réminiscences homériques. L’espace végétal semble composé d’un bouquet d’intertextes de nature endogène tandis que l’architecture palatiale combine structure archaïque et ornements hellénistiques. Nulle trace d’exotisme donc, mais un espace composé de réfé...

  8. Le palais d’Aiétès et son jardin chez Apollonios de Rhodes (Arg., III, v. 194-252. Un exemple de paysage-palimpseste antique ? The Palace of Aeetes and its Garden in Apollonius of Rhodes (Arg., III, lines 194-252. An example of ancient landscape as palimpsest? Il palazzo di Eeta e il suo giardino in Apollonio Rodio (Arg., III, 194-252. Un esempio di paesaggio-palinsesto antico?

    Directory of Open Access Journals (Sweden)

    Laury-Nuria André

    2012-07-01

    Full Text Available Lorsque le lecteur découvre au chant III des Argonautiques d’Apollonios de Rhodes l’espace du « paysage urbain » colque, au fur et à mesure de la progression visuelle des personnages, se dessine mentalement tout un espace littéraire fait de réminiscences homériques. L’espace végétal semble composé d’un bouquet d’intertextes de nature endogène tandis que l’architecture palatiale combine structure archaïque et ornements hellénistiques. Nulle trace d’exotisme donc, mais un espace composé de référents grecs typiques. Du fait de ces référents littéraires, la construction de l’espace palatial urbain emprunte sa configuration même au type d’écriture poétique sollicité par le poète épique : la réécriture. Comment comprendre alors que le palais d’Aiétès puisse être à l’image du palais du souverain grec hellénistique, image idéale d’une architecture s’inscrivant dans l’ordre divin ? Il faut voir ici non seulement la mise en image, l’illustration concrète via l’architecture et, partant, le « paysage urbain » qui se singularise par sa nature hybride, de la volonté de rapprocher Orient et Occident, mais aussi et surtout les moyens mêmes de cette mise en œuvre. Le palais et son jardin ne seraient alors qu’une promesse, un prototype d’un modèle idéal à étendre, grandeur nature, sur l’ensemble du territoire colque, et de l’oïkoumène tout entière.When the reader of the third book of Apollonius of Rhodes discovers, in the course of the characters’ visual progression, the space of a Colchian “urban landscape”, s/he mentally creates a literary space made of Homeric recollections. The garden space seems composed of a bouquet of intertexts of endogenous nature, whereas the palatial architecture combines archaic structure with hellenistic ornamentation. So no trace of the exotic, but a space composed of typical Greek references. As a result of these literary references, the construction of palatial urban space borrows its own configuration from the type of poetic writing the epic poet himself solicits: re-writing. How else can one explain that the palace of Aeetes can be the image of a hellenistic Greek royal palace, the perfect image of an architecture that inscribes itself into a divine order? One should see here not only the reconfiguration, the concrete illustration through the archictecture and, consequently, the urban “landscape” of such an unusual hybrid character, as a result of the wish to reconcile East and West, but also, perhaps especially, the means of its implementation. The palace and garden would then only be a promise, an ideal prototype to be extended, on a large scale, over all of the Colchian land and the entire oekoumene.Quando il lettore scopre, nel terzo libro delle Argonautiche di Apollonio Rodio, lo spazio del ‘paesaggio urbano’ colco, via che progredisce la visuale dei personaggi, viene tracciato mentalmente tutto uno spazio letterario fatto di reminiscenze omeriche. Lo spazio vegetale sembra composto da un insieme di intertesti endogeni, laddove l’architettura palaziale combina struttura arcaica e decorazioni ellenistiche. Nessuna traccia d’esotismo, quindi, ma uno spazio composto di tipici referenti greci. A partire da questi referenti letterari, la costruzione dello spazio palaziale urbano deve la sua stessa configurazione al tipo di scrittura poetica sollecitata dal poeta epico: la riscrittura. Come comprendere, allora, che il palazzo di Eeta possa essere a immagine del palazzo del sovrano greco ellenistico, immagine ideale di un’architettura che si inscrive nell’ordine divino? Occorre vedere qui non soltanto la raffigurazione, l’illustrazione concreta tramite l’architettura e, perciò, il ‘paesaggio urbano’ che si distingue per la sua natura ibrida, dalla volontà di avvicinare Oriente e Occidente, ma anche e soprattutto i mezzi stessi di questa attuazione. Il palazzo e il suo giardino non sarebbero allora altro che una promessa, un prototipo di un modello ideale da estendere, in scala naturale, all’insieme del territorio colco e dell’intera ecumene.

  9. SPECT assay of radiolabeled monoclonal antibodies. Final performance report, March 1992--November 1995

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1995-12-01

    Research is described in the following areas: development and evaluation quantitatively of reconstruction algorithms with improved compensations for attenuation, scatter, and geometric collimator response; evaluation of single photon emission computed tomography (SPECT) quantification of iodine 123 and astatine 211; and the development and evaluation of SPECT pinhole imaging for low and medium energy photons.

  10. Shelf-life of ɛ-lysyl-3-(trimethylstannyl)benzamide immunoconjugates, precursors for 211At labeling of antibodies

    DEFF Research Database (Denmark)

    Aneheim, Emma; Halleröd, Jenny; Albertsson, Per;

    2015-01-01

    Astatine-211 is possibly the most promising radionuclide for targeted α-particle therapy when it comes to the treatment of occult disseminated cancer. Preclinical research has proven effective, and patient studies have been initiated based on these results. However, a lack of production capacity...

  11. 10 CFR Appendix B to Part 20 - Annual Limits on Intake (ALIs) and Derived Air Concentrations (DACs) of Radionuclides for...

    Science.gov (United States)

    2010-01-01

    .... Actinium Ac 89 Aluminum Al 13 Americium Am 95 Antimony Sb 51 Argon Ar 18 Arsenic As 33 Astatine At 85... Curium Cm 96 Dysprosium Dy 66 Einsteinium Es 99 Erbium Er 68 Europium Eu 63 Fermium Fm 100 Fluorine F...

  12. SPECT assay of radiolabeled monoclonal antibodies. Final performance report, March 1992--November 1995

    International Nuclear Information System (INIS)

    Research is described in the following areas: development and evaluation quantitatively of reconstruction algorithms with improved compensations for attenuation, scatter, and geometric collimator response; evaluation of single photon emission computed tomography (SPECT) quantification of iodine 123 and astatine 211; and the development and evaluation of SPECT pinhole imaging for low and medium energy photons

  13. Multibeam collection for KN194-04: Multibeam data collected aboard Knorr from 2008-10-03 to 2008-10-31, departing from Reykjavik, Iceland and returning to Reykjavik, Iceland

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  14. Le palais d’Aiétès et son jardin chez Apollonios de Rhodes (Arg., III, v. 194-252). Un exemple de paysage-palimpseste antique ?

    OpenAIRE

    André, Laury-Nuria

    2013-01-01

    Lorsque le lecteur découvre au chant III des Argonautiques d’Apollonios de Rhodes l’espace du « paysage urbain » colque, au fur et à mesure de la progression visuelle des personnages, se dessine mentalement tout un espace littéraire fait de réminiscences homériques. L’espace végétal semble composé d’un bouquet d’intertextes de nature endogène tandis que l’architecture palatiale combine structure archaïque et ornements hellénistiques. Nul...

  15. Multibeam collection for KN194-02: Multibeam data collected aboard Knorr from 2008-09-01 to 2008-09-23, departing from Nuuk (Godthab), Greenland and returning to Nuuk (Godthab), Greenland

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  16. Insights into the Hydrocarbon Tolerance of Two Devosia Isolates, D. chinhatensis Strain IPL18T and D. geojensis Strain BD-c194T, via Whole-Genome Sequence Analysis

    OpenAIRE

    Hassan, Yousef I.; Lepp, Dion; Li, Xiu-Zhen; Zhou, Ting

    2015-01-01

    Hexachlorocyclohexane (HCH) was among the most commonly used pesticides after the Second World War. The extensive use of this hydrocarbon for almost six decades has created a contamination problem on a global scale, and bioremediation methods are being extensively explored. The reported ability of some Devosia species to grow in the presence of appreciable amounts of hydrocarbons (2,000 mg/kg of contaminated soil) is attracting closer attention. Here, we report the de novo genome assembly of ...

  17. Analisis Yuridis Terhadap Sengketa Kepemilikan Merek “Lexus” Antara Perusahaan PT. Toyota Jidosha Kabushiki Kaisha Dengan PT. Lexus Daya Utama (Studi Kasus Putusan No. 194.K/Pdt.Sus/2011)

    OpenAIRE

    Komalasari, Rini

    2016-01-01

    Brand is a mark which consists of pictures, names, words, alphabets, figures, color arrangement, of the combination of these elements which have distinctive power and are used in the activities of goods and services. The requirement/recognition on the right of brand for the brand ownership, according to constitution, is by registering it to the Directorate General of HKI as it is stipulated in Law on Brand No. 15/2001. This case began from the claim which was filed by PT. To...

  18. Preparing Children for Schools and Schools for Children. Notes, Comments = Preparer les enfants a l'ecole et adapter l'ecole aux enfants. Notes, Comments--No. 194.

    Science.gov (United States)

    United Nations Children's Fund, New York, NY.

    This paper critically examines evaluations of the effects of early childhood development programs in Third World countries. Introductory comments underscoring the importance of preschool interventions for the improvement of primary schools are followed by a section explaining the paper's analytical framework, which posits an interactive…

  19. Hurdles for a Broader Use of 211At and for the Synthesis of 211At-Labelled Radiopharmaceuticals at High Activities for Clinical Use

    International Nuclear Information System (INIS)

    One of the key impediments to the use of 211At is the very well known deleterious effect of high radiation fields caused by its alpha particles on the synthesis of 211At-labelled radiopharmaceuticals. This is problematic because radiolysis-mediated effects can produce diminishing efficiency of electrophilic astatination reactions due to increasing deposition of radiation dose with increasing activities and with the passage of the time. Astatine-211 has chemical properties that permit complex labelling strategies and a longer half-life than 213Bi that makes it more suitable when the targeting molecule does not gain immediate access to the tumour cells. The first clinical evaluation was published in 2001 [2] in patients with brain tumour. Although this study circumvents many of the challenges to entering clinical studies with 211At and many obstacles had to be surmounted before clinical studies could be initiated, several problems were encountered in maintaining efficient labelling with escalating radiation dose of α-particle even with fresh 211At elution [3]. Astatine-211 also has an additional hurdle to overcome before to its clinical application in labelled radiopharmaceuticals related with its production and distribution. Among the potential group of promising α- emitter it is the only one produced by cyclotrons, but due to the scarcity of cyclotrons equipped with 25−30 MeV α-particle beams, it will of necessity be utilized in distant locations from the site of production. It presents a major chemical challenge because the diminishing efficiency of electrophilic astatination reactions with the passage of the time is well known, a problem likely related to the radiolysis produced by the high LET (linear energy transfer) meaning that large amounts of energy are deposited in a highly localized manner. This problem has been most comprehensively investigated to understand and evaluate the role of the radiolysis effects of astatine alpha particles in the synthesis

  20. Production cross section of At radionuclides from $^{7}$Li+$^{\\textrm{nat}}$Pb and $^{9}$Be+$^{\\textrm{nat}}$Tl reactions

    CERN Document Server

    Maiti, Moumita

    2011-01-01

    Earlier we reported theoretical studies on the probable production of astatine radionuclides from $^{6,7}$Li and $^{9}$Be-induced reactions on natural lead and thalliun targets, respectively. For the first time, in this report, production of astatine radionuclides has been investigated experimentally with two heavy ion induced reactions: $^{9}$Be+$^{\\textrm{nat}}$Tl and $^{7}$Li+$^{\\textrm{nat}}$Pb. Formation cross sections of the evaporation residues, $^{207,208,209,210}$At, produced in (HI, xn) channel, have been measured by the stacked-foil technique followed by the off-line $\\gamma$-spectrometry at the low incident energies ($<$50 MeV). Measured excitation functions have been explained in terms of compound nuclear reaction mechanism using Weisskopf-Ewing and Hauser-Feshbach model. Absolute cross section values are lower than the respective theoretical predictions.

  1. Radiopharmaceutical Chemistry of Targeted Radiopharmaceutics. Synthesis of 211At-Labeled Radiopharmaceuticals at High Activities for Clinical Use

    International Nuclear Information System (INIS)

    Targeted α-particle radiotherapy is an appealing approach to cancer treatment because of the potential for delivering curative doses of radiation to tumor with minimal damage to normal tissue due to a range equivalent to only a few cell diameters. Compared with β-emitters they have significant advantages from a radiobiological perspective. The LET of 211At α-particles is more than 400 times higher than the β-particles emitted by 90Y, in addition the distance between ionizing events is almost the same as that between the two strands of DNA, yielding a high probability of creating non-repairable DNA damage. It gives the ability to kill cancer cells not compromised by hypoxia, dose rate effects or cell cycle position, enhancing their attractiveness for targeted radiotherapy. However, translation of the concept to the clinic has been slow, many obstacles had to be surmounted before clinical studies could be initiated, the first clinical evaluation of a 211At- labeled mAb was made in 2001. This study circumvents many of the challenges to entering clinical studies with 211At. But several problems were encountered in maintaining efficient labeling with escalating radiation dose of alpha-particle likely related to radiolysis. The impact of the radiolysis produced by the α-particle over the labeling chemistry is much higher in comparison with typical β-emitters due to a deposition of energy in the solvent in a highly localized manner two orders of magnitude per unit volume higher than 90Y or 131I. Due to these difficulties a comprehensive basic science study about the radiolytic effects of astatine alpha-particles over the synthesis of 211At-labeled radiopharmaceuticals was carried out. Its main goal was overcoming the problem of the synthesis of 211At-labeled radiopharmaceuticals at the high activities necessaries for therapy and also to extend the shelf life of astatine elutions. Briefly this study held several steps, the first one was to study the role of solvent

  2. 75 FR 9027 - Proposed Collection; Comment Request for Regulation Project

    Science.gov (United States)

    2010-02-26

    ...-80 (T.D. 7927), Amortization of Reforestation Expenditures (Sec. Sec. 1.194-2 and 1.194-4). DATES... Internet at Elaine.H.Christophe@irs.gov . SUPPLEMENTARY INFORMATION: Title: Amortization of Reforestation... section 194 allows taxpayers to elect to amortize certain reforestation expenditures over a 7-year...

  3. Decision of the German Federal Constitutional Court in proceedings instituted by the Land of Lower of Saxony, on the constitutionality of paragraph 2a, sub-para. 1(2) of paragraph 7 atomic energy act (AtG). Ruling as of 2 March 1999 (Az.: 2BvF 1/94)

    International Nuclear Information System (INIS)

    The legal question to be decided by the Federal Constitutional Court of Germany was whether a single ministry of the federal government can be vested, by way of a federal act, with the authority to issue general administrative regulations for implementation of the federal atomic energy act (AtG), to the governments of the federal Lands in matters where the Land governments act on behalf of the federal government, as e.g. in this case, concerning nuclear power plant licensing and radiation protection. The court ruling explains that the Constitution provides for exclusive rights of the federal government to issue general administrative regulations for the implementation of federal law. (orig./CB)

  4. Niels Bohr and China (II) A Collection of Related Historical Materials (194%2012)%尼耳斯·玻尔与中国(下) 有关历史资料汇编(1949-2012)

    Institute of Scientific and Technical Information of China (English)

    范岱年

    2012-01-01

    Niels Bohr was very warm to new China and Chinese people since the establishment of the People' s Republic of China in 1949. In contrast, the Chinese scientific community also paid great respect to him in due time. Mr. Guo Moruo, for example, the first President of the Chinese Academy of Sciences, used to invite Bohr to visit China in 1957. However, since 1952, influenced by the Soviet Union and guided by Marxism ideological concepts, the Chinese academia had improperly animadverted on Bohr' s philosophical views. Even in the 1970s, while the Soviet academia had changed their attitude to Bohr, a few critical articles were still published in two radical Chinese journals during the last stage of the Cultural Revolution. On the other hand, when Bohr died in 1962, the Chinese scientific community sent messages of condolence to his family. From 1962 to 1995, nearly 40 Chinese scholars had visited the Niels Bohr Institute at Copenhagen. In 1985, on the occasion of the 100th anniversary of Bohr' s birth, Chinese physics community held a ceremonious commemoration, singing high praise for this great scientist. Professor Ge Ge devoted all his life to introduce Bohr and his works into China, in particular by translating total 12 volumes of his Collected Works. In the 21 st century, although the political critique on Bohr' s philosophy in China has no long existed, the evaluation about Bohr, the Copenhagen School, as well as his view of the principle of complementarity, are still the most attractive topics which may cause continual and enthusiastic discussion.%1949年以后,中华人民共和国成立,玻尔一直对新中国和中国人民友好。中国科学界也一直尊敬、仰慕玻尔。1957年中国科学院院长郭沫若曾邀请玻尔访华。杨振宁曾会见玻尔。但自1952年开始,在苏联的影响下,在中共的领导下,中国学术界开始了对玻尔哲学观点的批判,到文革后期,苏联学者从批判玻尔转变为赞扬玻尔,中国两个刊物仍坚持批判玻尔。直到改革开放,情况才有所改变。1962年玻尔逝世,中国科学界向玻尔家属发去了唁电。自1962年起到1995年,中国有近40名学者访问了玻尔研究所,玻尔的儿子奥格.玻尔曾两次访问中国。1985年玻尔诞辰100周年,中国物理学界进行了隆重的纪念,对玻尔作了很高的评价。戈革为介绍玻尔和翻译玻尔全集奋斗了一生。21世纪以来,中国学术界已没有人对玻尔进行哲学批判,但对玻尔、对哥本哈根学派、对互补观点的评价仍是争论的话题。

  5. Dicty_cDB: SFA691 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 510164 |AJ510164.1 Cloning vector pDXA-3strep. 194 7e-47 2 X85119 |X85119.1 Artificial... sequences cloning vector DNA pDXA-3H. 194 7e-47 2 X85122 |X85122.1 Artificial sequences cloning vector... DNA pDXA-HY. 194 7e-47 2 AJ510165 |AJ510165.1 Cloning vector pDXA-3FLAG. 194 7e-47 2 X85118 |X85118.1 Artificial... sequences cloning vector DNA pDXA-3C. 194 7e-47 2 X85123 |X85123.1 Artificial... sequence. 194 7e-47 2 X85120 |X85120.1 Artificial sequences cloning vector DNA pDXD-3H. 194 8e-47 2 AJ51016

  6. Inclusive measurement of (p,πsup(-)xn) double charge exchange reactions on bismuth from threshold to 800 MeV

    International Nuclear Information System (INIS)

    The energy dependence of the total angle-integrated cross section for the production of astatine isotopes from (p,πsup(-)xn) double charge exchange reactions on bismuth (sup(209)Bi) was measured from 120 to 800 MeV using activation and radiochemical techniques. Chemical yields were estimated by direct radioassaying of sup(211)At activity in thin (approximately 1 mg/cmsup(2)), irradiated bismuth targets. Calculations of the contributions of secondary (2-step) reactions to these measured astatine yields were performed, based partially upon the observed sup(211)At activity although even at the highest energies, the contribution to products lighter than sup(207)At was negligible. These data for products with as many as 7 neutrons removed from the doubly coherent product (sup(210)At) display nearby gaussian shapes for the mass distributions of the astatine residues with the maximum occurring for about sup(204)At. The most probable momentum transfer deduced from these distributions for the initial πsup(-) production step was 335 MeV/c. The observed excitation functions display a behaviour similar to that observed for the yield of sup(210)Po from a (p,πsup(O)) reaction on sup(209)Bi, but radically different from that observed for inclusive πsup(-) reactions on a heavy nucleus. These data are discussed in terms of recent theoretical approaches to negative pion production from bismuth. In addition, a simple, schematic model is developed to treat the rapidly decreasing percentage of the total inclusive πsup(-) emission which is observed for this double charge exchange reaction. This model reflects the capacity of a nucleus to a source of internal energetic protons

  7. Human radiation studies: Remembering the early years: Oral history of Dr. Patricia Wallace Durbin, Ph.D., conducted November 11, 1994

    International Nuclear Information System (INIS)

    This report is a transcript of an interview of Dr. Patricia Wallace Durbin by representatives of the US DOE Office of Human Radiation Research. Dr. Durbin was selected for this interview because of her knowledge of the human plutonium injections and her recollections of key figures, especially Joseph Hamilton. After a brief biographical sketch Dr. Durbin discusses her loss of research funding from DOE, her recollections concerning research into strontium metabolism as part of Project Sunshine, her recollections relating to the rationale for studies of human metabolism of radionuclides, her remembrances of Dr. Hamilton's Astatine and Plutonium research, and her experiences in gathering archival records concerning these researches

  8. EFFECT OF MECHANICAL PROPERTIES OF MARTENSITE AND LOADING RATE ON DUAL PHASE STEELS

    OpenAIRE

    BAYRAM, Ali

    1998-01-01

    In this study, steel sheet materials were used in order to obtain dual-phase steel. Specimens for this purpose have been annealed in ferrite + astatine regions at the temperatures of 740, 760, 800 and 820 °C. The specimens were annealed at the different temperatures with corresponding times 20, 40 and 60 minutes and quenched into water. As a result of this dual-phase steels at different ferrite + martensite ratio were produced. Sheet specimens were tested at the range of loading rates of 1...

  9. Dicty_cDB: Contig-U00979-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tttttttaatgaacnaa 134 Query: 135 naaattcnagtaaaatcnaaagagnttatgatattaccnatgntntaagnccnttaggtc 194 ||||||||||...|||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 135 naaattcnagtaaaatcnaaagagnttatgatattaccnatgntnt...) Strand = Plus / Minus Query: 125 aatgaacnaanaaattcnagtaaaatcnaaagagnttatgatattaccna...agtaaaatcnaaagagnttatgatattaccnatgntntaagn 25 Query: 185 ccnttaggtctaatccgnaaaac 207 |||||||||||||||||||||||

  10. Alpha-decay studies of the new isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At

    CERN Document Server

    Kettunen, H; Grahn, T; Greenlees, P T; Jones, P; Julin, R; Juutinen, S; Keenan, A; Kuusiniemi, P; Leino, M; Leppaenen, A P; Nieminen, P; Pakarinen, J; Rahkila, P; Uusitalo, J

    2003-01-01

    Detailed alpha-decay studies have been performed for the neutron-deficient isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At. The nuclei were produced in fusion-evaporation reactions of sup 5 sup 4 Fe and sup 5 sup 6 Fe ions with a sup 1 sup 4 sup 1 Pr target. The fusion products were separated in-flight using a gas-filled recoil separator and implanted into a position-sensitive silicon detector. The isotopes were identified using position, time and energy correlations between the implants and subsequent alpha-decays. Three alpha-decaying states were identified for sup 1 sup 9 sup 3 At and two for sup 1 sup 9 sup 1 At. The spin and parity of the initial states in the astatine isotopes were deduced based on unhindered alpha-decays to states in the bismuth daughter nuclei. In both astatine isotopes the 1/2 sup + intruder state was determined to be the ground state and a 7/2 sup - state to be the first-excited state. In sup 1 sup 9 sup 3 At the alpha-decay of the 13/2 sup + state was observed in coincidence...

  11. Rationalization of the solvation effects on the AtO+ ground-state change.

    Science.gov (United States)

    Ayed, Tahra; Réal, Florent; Montavon, Gilles; Galland, Nicolas

    2013-09-12

    (211)At radionuclide is of considerable interest as a radiotherapeutic agent for targeted alpha therapy in nuclear medicine, but major obstacles remain because the basic chemistry of astatine (At) is not well understood. The AtO(+) cationic form might be currently used for (211)At-labeling protocols in aqueous solution and has proved to readily react with inorganic/organic ligands. But AtO(+) reactivity must be hindered at first glance by spin restriction quantum rules: the ground state of the free cation has a dominant triplet character. Investigating AtO(+) clustered with an increasing number of water molecules and using various flavors of relativistic quantum methods, we found that AtO(+) adopts in solution a Kramers restricted closed-shell configuration resembling a scalar-relativistic singlet. The ground-state change was traced back to strong interactions, namely, attractive electrostatic interactions and charge transfer, with water molecules of the first solvation shell that lift up the degeneracy of the frontier π* molecular orbitals (MOs). This peculiarity brings an alternative explanation to the highly variable reproducibility reported for some astatine reactions: depending on the production protocols (with distillation in gas-phase or "wet chemistry" extraction), (211)At may or may not readily react. PMID:23944251

  12. Pamjat teksta i tekst kak pamjat / Ülle Pärli

    Index Scriptorium Estoniae

    Pärli, Ülle

    1999-01-01

    Bibl. lk. 194. Kokkuvõtted eesti k. "Teksti mälu ja tekst kui mälu" ning inglise k. "The memory of a text and text as a memory", lk. 194-195. Jossif Brodski luuletusest "Järelsõna valmile" ("Posleslovije k basne")

  13. 77 FR 3636 - Federal Acquisition Regulation; Brand-Name Specifications; Correction

    Science.gov (United States)

    2012-01-25

    ... at 77 FR 194 on January 3, 2012. DATES: Effective Date: February 2, 2012. FOR FURTHER INFORMATION..., which published in the Federal Register at 77 FR 189 on January 3, 2012. Correction In the final rule document appearing at 77 FR 189 on January 3, 2012, on page 194, first column, amendatory instruction...

  14. 40 CFR 75.33 - Standard missing data procedures for SO2, NOX, Hg, and flow rate.

    Science.gov (United States)

    2010-07-01

    ...-assured monitor operating hours. X Use this algorithm for moisture except when Equation 19-3, 19-4 or 19-8... algorithm for moisture only when Equation 19-3, 19-4 or 19-8 in Method 19 in appendix A-7 to part 60 of...

  15. EST Table: DC555227 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DC555227 E_FL_wd--_09J09_F_0 10/09/28 51 %/194 aa ref|XP_002094603.1| GE20109 [Dros...ophila yakuba] gb|EDW94315.1| GE20109 [Drosophila yakuba] 10/09/02 51 %/194 aa FBpp0265119|DyakGE20109-PA 10

  16. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    CERN Document Server

    Marsh, B A; Imai, N; Seliverstov, M D; Rothe, S; Sels, S; Capponi, L; Rossel, R E; Franchoo, S; Wendt, K; Focker, G J; Kalaninova, Z; Sjoedin, A M; Popescu, L; Nicol, T; Huyse, M; Radulov, D; Atanasov, D; Kesteloot, N; Borgmann, Ch; Cocolios, T E; Lecesne, N; Ghys, L; Pauwels, D; Rapisarda, E; Kreim, S; Liberati, V; Wolf, R N; Andel, B; Schweikhard, L; Lane, J; Derkx, X; Kudryavtsev, Yu; Zemlyanoy, S G; Fedosseev, V N; Lynch, K M; Rosenbusch, M; Van Duppen, P; Lunney, D; Manea, V; Barzakh, A E; Andreyev, A N; Truesdale, V; Flanagan, K T; Molkanov, P L; Koester, U; Van Beveren, C; Wienholtz, F; Goodacre, T Day; Antalic, S; Bastin, B; De Witte, H; Fink, D A; Fedorov, D V

    2013-01-01

    At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar fr...

  17. Development of 211At Chemistry for Labelling Biomolecules

    International Nuclear Information System (INIS)

    Our studies have demonstrated that high recovery of 211At can be obtained using a “wet chemistry” approach to isolation from the bismuth target. We have also demonstrated that direct labelling of antibody-B10 conjugates with 211At can be performed in high yields, and that the astatinated antibodies are stable to in vivo deastatination. While these results will allow us to enter clinical studies with 211At-labelled antibodies, the chemistry associated with 211At is not fully understood. Therefore, it is important that many more basic studies to be conducted with 211At, so the optimal labelling reagent for each type of disease-targeting agent becomes apparent

  18. Alpha particle induced DNA damage and repair in normal cultured thyrocytes of different proliferation status

    DEFF Research Database (Denmark)

    Lyckesvärd, Madeleine Nordén; Delle, Ulla; Kahu, Helena;

    2014-01-01

    Childhood exposure to ionizing radiation increases the risk of developing thyroid cancer later in life and this is suggested to be due to higher proliferation of the young thyroid. The interest of using high-LET alpha particles from Astatine-211 ((211)At), concentrated in the thyroid by the same...... levels of γH2AX decreased during the first 24h in both cycling and stationary cultures and complete repair was seen in all cultures but cycling cells exposed to (211)At. Compared to stationary cells alpha particles were more harmful for cycling cultures, an effect also seen at the pChk2 levels...... cultures at a modest level of damage, clearly demonstrating that cell cycle status influences the relative effectiveness of alpha particles....

  19. EFFECT OF MECHANICAL PROPERTIES OF MARTENSITE AND LOADING RATE ON DUAL PHASE STEELS

    Directory of Open Access Journals (Sweden)

    Ali BAYRAM

    1998-03-01

    Full Text Available In this study, steel sheet materials were used in order to obtain dual-phase steel. Specimens for this purpose have been annealed in ferrite + astatine regions at the temperatures of 740, 760, 800 and 820 °C. The specimens were annealed at the different temperatures with corresponding times 20, 40 and 60 minutes and quenched into water. As a result of this dual-phase steels at different ferrite + martensite ratio were produced. Sheet specimens were tested at the range of loading rates of 10, 50 and 259 mm/min. Strength properties of dual-phase steels were investigated depending on annealing temperature, ratio of martensite and loading rate.

  20. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, B.A., E-mail: bruce.marsh@cern.ch [CERN, CH-1211 Geneva (Switzerland); Andel, B. [Comenius University, Bratislava (Slovakia); Andreyev, A.N. [University of York, Department of Physics, York YO10 5DD (United Kingdom); Antalic, S. [Comenius University, Bratislava (Slovakia); Atanasov, D. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Barzakh, A.E. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Bastin, B. [Grand Accérateur National d’Ions Lourds (GANIL), Bd Henri Becquerel, F-14076 Caen (France); Borgmann, Ch. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Capponi, L. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Cocolios, T.E.; Day Goodacre, T. [CERN, CH-1211 Geneva (Switzerland); University of Manchester, Manchester (United Kingdom); Dehairs, M. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Derkx, X. [University of the West of Scotland, School of Engineering, Paisley PA1 2BE (United Kingdom); De Witte, H. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fedorov, D.V. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Fedosseev, V.N.; Focker, G.J. [CERN, CH-1211 Geneva (Switzerland); Fink, D.A. [Ruprecht-Karls Universität, Seminarstr. 2, 69117 Heidelberg (Germany); CERN, CH-1211 Geneva (Switzerland); Flanagan, K.T. [University of Manchester, Manchester (United Kingdom); Franchoo, S. [CSNSM-IN2P3-CNRS, Université Paris-Sud, 91406 Orsay (France); and others

    2013-12-15

    Highlights: • Upgrade of the lasers, detectors and data acquisition for in-source resonance ionization spectroscopy at ISOLDE. • First use of the ISOLTRAP MR-ToF MS in combination with laser spectroscopy at ISOLDE. • Resonance ionization of astatine for the study of its nuclear structure. -- Abstract: At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar free ionization using the Laser Ion Source Trap, LIST (Po); isobar selective particle identification using the multi-reflection time-of-flight mass separator (MR-ToF MS) of ISOLTRAP (Au, At). These are summarized as part of an overview of the current status of the in-source resonance ionization spectroscopy setup at ISOLDE.

  1. EST Table: FY010502 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY010502 bmov30g16 11/11/04 100 %/194 aa dbj|BAB16697.1| annexin [Bombyx mori] dbj|BAB16698.1| anne....9a#CE23956#WBGene00003589#locus:nex- 2#Annexin#status:Confirmed#UniProt:Q27512#protein_id:CAA 82571.2 11/11...62 %/194 aa gnl|Amel|GB16448-PA 11/11/04 72 %/194 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] NM_001043376 bmov ...

  2. Theoretical analysis of an Uqp(u2) model for the congruent superdeformed rotational bands

    International Nuclear Information System (INIS)

    Superdeformed rotational bands in 191-192-193-194Hg are analyzed by means of the Uqp(u2) model. An overall and excellent agreement between the calculated and observed spectra Eγ, kinematic moment of inertia J(1) and dynamic moment of inertia J(2), the aligned angular momentum (i = ω (J(1)(191-193-194Hg)-J(1)(192Hg))) is obtained. Further more, the nuclear softness in 191-192-193-194Hg are calculated by means of the Uqp(u2) model and drawn into the nuclear configuration analysis

  3. Dicty_cDB: Contig-U13509-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 78 Start point 4427081 End point 4426057 Strand (PLUS/MINUS) MINUS Number of clones 2 Number of EST 2 Link t... 0.0 Identities = 487/487 (100%) Strand = Plus / Plus Query: 431 tactacttcaacaaccacaccatcaaacagtttatttggaaca...17 Score = 385 bits (194), Expect = e-107 Identities = 194/194 (100%) Strand = Plus / Plus Query: 200 aacatc... = 137 bits (69), Expect = 3e-32 Identities = 69/69 (100%) Strand = Plus / Plus Q...pect = 3e-29 Identities = 73/73 (100%) Strand = Plus / Plus Query: 953 ttctaccacctcaacaaccaccacaccatnaactggn

  4. Innovaatiline mõtlemine nõuab juhilt julgust kastist välja tulla / Alexander Kotchubei

    Index Scriptorium Estoniae

    Kotchubei, Alexander, 1963-

    2005-01-01

    Ilmunud ka: Juhi ideelaegas. - Tallinn, 2006, lk. 194-196. Uuenduslikkuse aluseks on konkurentidest efektiivsem mõtlemine. Vt. samas: Tänapäeva juht peab olema avatud ja riskijulge; Uusi ideid soodustavad muudatused mõtteviisis

  5. Fire Management Plan: Upper Mississippi River National Wildlife and Fish Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Upper Mississippi River National Wildlife and Fish Refuge consists of approximately 194,000 acres of wooded islands, waters and marshes extending southward...

  6. Drug: D06649 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available atment of patients undergoing percutaneous coronary interventions Monoclonal antibody glycoprotein alphaIIb/...ADYEKHK VYACEVTHQG LSSPVTKSFN RGEC (Disulfide bridge: 23-88; 134-194) Peptide Tre

  7. 76 FR 51998 - Announcement of Funding Awards for the Service Coordinators in Multifamily Housing Fiscal Year 2009

    Science.gov (United States)

    2011-08-19

    ... Recipient: Catholic Charities of St. Paul and Minneapolis Property Name: Mary Hall SRO Occupancy Program... City: Richmond Assisted Units: 249 Amount: $194,416 Recipient: Elm Manor Homes, Inc. Property Name:...

  8. Dicósimo, Daniel y Simonassi, Silvia (comp., Trabajadores y empresarios en la Argentina del siglo XX: indagaciones desde la historia social

    Directory of Open Access Journals (Sweden)

    Valeria Ianni

    2013-01-01

    Full Text Available Dicósimo, Daniel y Simonassi, Silvia (comp., Trabajadores y empresarios en la Argentina del siglo XX: indagaciones desde la historia social, Prohistoria ediciones, Rosario, 2011 (194 págs..

  9. Dicty_cDB: Contig-U13692-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available D504Z ,194,812 Translated Amino Acid sequence mv*lqsiwvvvvwigy*livtf*lnkiqywlgiwqsq*hvacfiymignqiqyfieiyqq r...fvf*nsckylskk Frame C: mv*lqsiwvvvvwigy*livtf*lnkiqywlgiwqsq*hvacfiymignqiqyfieiy

  10. Eimuntas Nekroshiuse teatripoeetika / Ruta Mazheikiene ; tõlk. Tiina Kattel

    Index Scriptorium Estoniae

    Mazheikiene, Ruta

    2004-01-01

    E. Nekroshiuse lavastustele iseloomulikest joontest, toetudes tema lavastustele "Hamlet" "Macbeth", "Othello", "Onu Vanja", "Nina". Samuti näitlejatega töötamise strateegiast. Kasut. kirjandus, lk. 194-195

  11. Effect of Family Structure on Marital Attitudes of Adolescents.

    Science.gov (United States)

    Ganong, Lawrence; And Others

    1981-01-01

    Assesses the effect of exposure to different family structures (single parent families, reconstituted families, intact families) on the marital socialization of 127 males and 194 female adolescents. (Author/CM)

  12. First indication of population of superdeformed states by incomplete fusion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Kaci, M.; Azaiez, F.; Bouneau, S.; Duprat, J.; Bourgeois, C.; Sergolle, H. [IPN, IN2P3-CNRS, Bat 104-108, F-91406 Orsay (France); Gueorguieva, E.; Porquet, M.G.; Deloncle, I.; Dozie, N. [CSNSM, IN2P3-CNRS, Bat 104, F-91405 Orsay (France); Aleonard, M.M. [CENBG, IN2P3-CNRS, F-33170 Gradignan (France); Astier, A.; Ducroux, L.; Meyer, M.; Redon, N. [IPN, IN2P3-CNRS Villeurbanne (France); Baldsiefen, G.; Korten, W.; van Severen, U.J. [ISKP, University of Bonn, Nussallee 14-16, D-53115 Bonn (Germany); Beausang, C.W. [Oliver Lodge Laboratory, University of Liverpool, P.O. Box 147, Liverpool L69 3BX (United Kingdom); Beck, F.A.; Curien, D.; Gall, B.J.; Prevost, D. [CRN, IN2P3-CNRS, F-67037 Strasbourg (France); Sharpey-Schafer, J.F. [NAC, Faure P.O. Box 72, ZA 7131 Cape Town (South Africa)

    1997-08-01

    The high-spin normally deformed and superdeformed states of {sup 194}Hg have been populated in an exit channel of the {sup 16}O+{sup 186}W reaction at 110 MeV bombarding energy. The Doppler shift analysis of the energies of the {gamma} transitions de-exciting both normally deformed and superdeformed states in {sup 194}Hg indicates a lower recoil velocity of the {sup 194}Hg nucleus compared to that of the {sup 196}Pb nucleus obtained from the 6n exit channel of the complete-fusion compound nucleus. This suggests that incomplete fusion plays the main role in the population of normally deformed and superdeformed states of {sup 194}Hg in this reaction. {copyright} {ital 1997} {ital The American Physical Society}

  13. 75 FR 33669 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-06-14

    .... Title: LR-189-80 (T.D. 7927) Final Amortization of Reforestation Expenditures Abstract: 26 U.S.C. 194(a) allows taxpayers to elect to amortize certain reforestation expenditures over a 7-year period if...

  14. Dicty_cDB: Contig-U16173-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available japonicum isolate Anhu... 200 3e-49 AB367929_1( AB367929 |pid:none) Theileria sergenti CCTeta gene for... 19...ana AT5g20890/F22... 199 4e-49 AB367931_1( AB367931 |pid:none) Theileria sergenti CCTeta mRNA for... 199 4e-.... 194 2e-47 AB367930_1( AB367930 |pid:none) Theileria sergenti CCTeta gene for... 194 2e-47 BC065324_1( BC06

  15. A new species of elongate unpatterned moray eel of the genus Gymnothorax (Muraenidae: Muraeninae) from the Bay of Bengal.

    Science.gov (United States)

    Mohapatra, Anil; Ray, Dipanjan; Smith, David G; Mishra, Subhrendu Sekhar

    2016-08-16

    An elongate, brown unpatterned moray eel, Gymnothorax indicus sp. nov., is described based on four specimens collected from the northern Bay of Bengal. The new species is differentiated from other elongate, unpatterned moray eels in having the following combination of characters: anus at about mid-point of body, preanal length 2.0 in total length; snout blunt and short; dorsal fin margin black, 5 mandibular pores; maxillary teeth uniserial, sharp and depressible, total vertebrae 194 (MVF: 9-79-194).

  16. A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk

    Energy Technology Data Exchange (ETDEWEB)

    Mohrenweiser, H W; Han, J; Hankinson, S E; De Vivo, I; Spiegelman, D; Tamimi, R M; Colditz, G A; Hunter, D J

    2004-01-15

    The XRCC1 protein is involved in the base excision repair pathway through interactions with other proteins. Polymorphisms in the XRCC1 gene may lead to variation in repair proficiency and confer inherited predisposition to cancer. We prospectively assessed the associations between polymorphisms and haplotypes in XRCC1 and breast cancer risk in a nested case-control study within the Nurses' Health Study (incident cases, n 1004; controls, n 1385). We further investigated gene-environment interactions between the XRCC1 variations and plasma carotenoids on breast cancer risk. We genotyped four haplotype-tagging single nucleotide polymorphisms Arg {sup 194}Trp, C26602T, Arg{sup 399}Gln, and Gln{sup 632}Gln in the XRCC1 gene. Five common haplotypes accounted for 99% of the chromosomes in the present study population of mostly Caucasian women. We observed a marginally significant reduction in the risk of breast cancer among {sup 194}Trp carriers. As compared with no-carriers, women with at least one {sup 194}Trp allele had a multivariate odds ratio of 0.79 (95% of the confidence interval, 0.60 -1.04). The inferred haplotype harboring the {sup 194}Trp allele was more common in controls than in cases (6.6 versus 5.3%, P 0.07). We observed that the Arg {sup 194}Trp modified the inverse associations of plasma -carotene level (P, ordinal test for interaction 0.02) and plasma -carotene level (P, ordinal test for interaction 0.003) with breast cancer risk. No suggestion of an interaction was observed between the Arg {sup 194}Trp and cigarette smoking. Our results suggest an inverse association between XRCC1 {sup 194}Trp allele and breast cancer risk. The findings of the effect modification of the Arg {sup 194}Trp on the relations of plasma -and -carotene levels with breast cancer risk suggest a potential protective effect of carotenoids in breast carcinogenesis by preventing oxidative DNA damage.

  17. An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV.

    Directory of Open Access Journals (Sweden)

    Jennifer D Watkins

    Full Text Available Neutralizing antibodies have been shown to protect macaques against SHIV challenge. However, genetically diverse HIV-1 clades have evolved, and a key question left unanswered is whether neutralizing antibodies can confer cross-clade protection in vivo. The novel human monoclonal antibody HGN194 was isolated from an individual infected with an HIV-1 clade AG recombinant circulating recombinant form (CRF. HGN194 targets an epitope in the third hypervariable loop (V3 of HIV-1 gp120 and neutralizes a range of relatively neutralization-sensitive and resistant viruses. We evaluated the potential of HGN194 to protect infant rhesus monkeys against a SHIV encoding a primary CCR5-tropic HIV-1 clade C envelope. After high-dose mucosal challenge, all untreated controls became highly viremic while all HGN194-treated animals (50 mg/kg were completely protected. When HGN194 was given at 1 mg/kg, one out of two monkeys remained aviremic, whereas the other had delayed, lower peak viremia. Interestingly, all protected monkeys given high-dose HGN194 developed Gag-specific proliferative responses of both CD4+ and CD8+ T cells. To test whether generation of the latter involved cryptic infection, we ablated CD8+ cells after HGN194 clearance. No viremia was detected in any protected monkeys, thus ruling out virus reservoirs. Thus, induction of CD8 T-cell immunity may have resulted from transient "Hit and Run" infection or cross priming via Ag-Ab-mediated cross-presentation. Together, our data identified the HGN194 epitope as protective and provide proof-of-concept that this anti-V3 loop mAb can prevent infection with sterilizing immunity after challenge with virus of a different clade, implying that V3 is a potential vaccine target.

  18. EST Table: AV398126 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AV398126 NV021158 10/09/28 96 %/194 aa pdb|2I1J|A Chain A, Moesin From Spodoptera Frugiperda At 2.1 Angstrom...strom Resolution gb|ABK60307.1| moesin [Spodoptera frugiperda] 10/08/28 87 %/194 aa...s Resolution pdb|2I1K|A Chain A, Moesin From Spodoptera Frugiperda Reveals The Coiled-Coil Domain At 3.0 Ang

  19. MORPHOLOGICAL ALTERATIONS OF STAPHYLOCOCCUS AUREUS CAUSED BY ARYL ALIPHATIC AMINOALCOHOL DERIVATIVE

    Directory of Open Access Journals (Sweden)

    Dronova M.

    2015-05-01

    Full Text Available Increasing of antimicrobial resistance has created a critical need of the novel antimicrobial agents. One of the promising chemical classes for its development are aryl aliphatic aminoalcohols. New compounds of this class were synthesized at the Institute of organic chemistry (Kiev, Ukraine, by Y. Korotkiy. After the screening studies compound KVM-194 was selected as the potent antistaphylococcal agent. The aim of the study was to examine ultrastructural changes in the bacterial cells under the influence of the compound KVM-194. Materials and methods. Staphylococcus aureus ATCC 25923 was used in all experiments. The minimum inhibitory concentration was determined by serial macrodilution method in Mueller-Hinton broth. Bacteria were exposed to the 0,5 MIC and 5 MICs of the KVM- 194 for 1 h and 24 h. Ultrastructure of intact and treated Staphylococcus aureus cells was examined by transmission electron microscopy after contrasting by osmium tetraoxide and lead citrate. Results and Discussion. The compound KVM-194 possesses a distinct antibacterial activity against Staphylococcus aureus, the minimum inhibitory concentration is 1.25 μg/ml. We found that exposure to KVM-194 at a subinhibitory concentration resulted in alterations of the cell morphology even after 1 h of treatment. The roughness of the cell surface and emerging of the intracellular particles of different electron density were observed. Increase of the incubation time to 24 h led to detachment of membrane from cytoplasm, multimembrane structures within cells emergence and formation of nonpolar septum. 1 h exposition to suprainhibitory concentration of KVM-194 resulted in nucleoid fragmentation, septum abnormalities and necrosis of some cells. We found that increasing of the incubation period to 24 h led to exacerbation of alterations: cell wall rupture, leakage of cytoplasm and a large number of lysed cells were registered. Conclusion. Observed alterations, suggest the possible

  20. Properties of Nuclear Superdeformed Rotational Bands in A~190 Mass Region

    Directory of Open Access Journals (Sweden)

    Khalaf A. M.

    2014-10-01

    Full Text Available Two-parameters formula based on the conventional collective rotational model is ap- plied to describe superdeformed rotational bands (SDRB’s in nuclei in the A 190 mass region, namely the five SDRB’s 192 Hg(SD1, 194 Hg(SD1, 194 Hg(SD2, 194 Pb(SD1 and 194 Pb(SD2. The bandhead spins of the observed levels have been ex- tracted by first and second-hand estimation corresponding to pure rotator and our pro- posed formula respectively by plotting the E-Gamma Over Spin (EGOS versus spin. A computer simulated search program is used to extract the model parameters in order to obtain a minimum root mean square (rms deviation between the calculated and the experimental transition energies The values of spins resulting from second estimation method are excellent consistent with spin assignment of other models. The calculated transition energies, level spins, rotational frequencies, kinematic and dynamic moments of inertia are systematically examined. The di ff erence in - ray transition energies ∆ E between transitions in the two isotones 192 Hg(SD1 and 194 Pb(SD1 were small and con- stant up to rotational frequency ℏ ! 0.25 MeV. Therefore, these two bands have been considered as identical bands. The ∆ I = 2 energy staggering observed in 194 Hg(SD1 and 194 Hg(SD2 of our selected SDRB’s are also described from a smooth reference representing the finite difference approximation to the fourth order derivative of the transition energies at a given spin.

  1. Inhibition of Metastatic Potential in Breast Carcinoma In Vivo and In Vitro through Targeting VEGFRs and FGFRs

    Directory of Open Access Journals (Sweden)

    Ming-Hsien Chien

    2013-01-01

    Full Text Available Angiogenesis and lymphangiogenesis are considered to play key roles in tumor metastasis. Targeting receptor tyrosine kinases essentially involved in the angiogenesis and lymphangiogenesis would theoretically prevent cancer metastasis. However, the optimal multikinase inhibitor for metastasis suppression has yet to be developed. In this study, we evaluated the effect of NSTPBP 0100194-A (194-A, a multikinase inhibitor of vascular endothelial growth factor receptors (VEGFRs/fibroblast growth factor receptors (FGFRs, on lymphangiogenesis and angiogenesis in a mammary fat pad xenograft model of the highly invasive breast cancer cell line 4T1-Luc+. We investigated the biologic effect of 194-A on various invasive breast cancer cell lines as well as endothelial and lymphatic endothelial cells. Intriguingly, we found that 194-A drastically reduced the formation of lung, liver, and lymph node metastasis of 4T1-Luc+ and decreased primary tumor growth. This was associated with significant reductions in intratumoral lymphatic vessel length (LVL and microvessel density (MVD. 194-A blocked VEGFRs mediated signaling on both endothelial and lymphatic endothelial cells. Moreover, 194-A significantly inhibited the invasive capacity induced by VEGF-C or FGF-2 in vitro in both 4T1 and MDA-MB231 cells. In conclusion, these experimental results demonstrate that simultaneous inhibition of VEGFRs/FGFRs kinases may be a promising strategy to prevent breast cancer metastasis.

  2. Identification of Specific Effect of Chloride on the Spectral Properties and Structural Stability of Multiple Extracellular Glutamic Acid Mutants of Bacteriorhodopsin

    Science.gov (United States)

    Lazarova, Tzvetana; Mlynarczyk, Krzysztof; Querol, Enric; Tenchov, Boris; Filipek, Slawomir; Padrós, Esteve

    2016-01-01

    In the present work we combine spectroscopic, DSC and computational approaches to examine the multiple extracellular Glu mutants E204Q/E194Q, E204Q/E194Q/E9Q and E204Q/E194Q/E9Q/E74Q of bacteriorhodopsin by varying solvent ionic strength and composition. Absorption spectroscopy data reveal that the absorption maxima of multiple EC Glu mutants can be tuned by the chloride concentration in the solution. Visible Circular dichroism spectra imply that the specific binding of Cl- can modulate weakened exciton chromophore coupling and reestablish wild type-like bilobe spectral features of the mutants. The DSC data display reappearance of the reversible thermal transition, higher Tm of denaturation and an increase in the enthalpy of unfolding of the mutants in 1 M KCl solutions. Molecular dynamics simulations indicate high affinity binding of Cl- to Arg82 and to Gln204 and Gln194 residues in the mutants. Analysis of the experimental data suggests that simultaneous elimination of the negatively charged side chain of Glu194 and Glu204 is the major cause for mutants’ alterations. Specific Cl- binding efficiently coordinates distorted hydrogen bonding interactions of the EC region and reconstitutes the conformation and structure stability of mutated bR in WT-like fashion. PMID:27657718

  3. Search for new candidates for the neutrino-oriented mass determination by electron-capture

    CERN Multimedia

    Herfurth, F; Boehm, C; Blaum, K; Beck, D

    2008-01-01

    This proposal is part of an extended program dedicated to the neutrino-mass determination in the electron-capture sector, which aims at ultra-precise mass measurements by Penning traps in combination with cryogenic micro-calorimetry for atomic de-excitation measurements. Here, precise mass measurements with ISOLTRAP are proposed for the orbital electron-capture nuclides $^{194}$Hg and $^{202}$Pb, as well as their daughters, with the goal to determine accurately their Q-values. These values are expected to be the smallest ones among a great variety of known electron-capture precursors. Therefore, these nuclides are strong candidates for an improved electron-neutrino mass determination. We ask for 8 shifts of on-line beam at ISOLDE for mass measurements of $^{194}$Hg, $^{194}$ Au, $^{202}$Pb, and $^{202}$Tl at ISOLTRAP.

  4. An overview of the recent results on fission dynamics from the NAND facility

    Indian Academy of Sciences (India)

    B R Behera

    2015-08-01

    This paper summarizes the results of some of the recent fusion–fission experiments carried out at the National Array of Neutron Detectors (NAND) Phase-01 installed at the Pelletron+LINAC accelerator facility of Inter-University Accelerator Centre (IUAC), New Delhi. Pre-scission neutron multiplicity excitation functions are measured for the 213,215,217Fr, 210,212,214,216Rn and 206,210Po compound nuclei populated through the fusion of the 19F+194,196,198Pt, 16,18O+194,198Pt and 12C+194,198Pt systems, respectively. Pre-scission neutron yields from these reactions are compared with the extensive statistical model calculations to look for the effects due to the compound nucleus shell closure, / ratio of the compound nucleus, magnitude of the saddle-point shell corerction and fission time-scale.

  5. Superelasticity of TiPdNi Alloys with and without Rare Earth Ce Addition

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Ti50.6Pda0Ni19.4 and Ti51Pd2sNi21 (Ce) alloys have been prepared under various temperatures for long time annealing. Differential scanning calorimetery (DSC), X-ray diffraction (XRD) and tensile test were employed to investigate the phase transformation behavior and superelasticity of the alloys. It has been found that the phase transformation temperature of Ti50.6Pd30Ni19.4 is about 40℃ higher than that of Ti51Pd28Ni21(Ce), and do not change much with different annealed temperature. Obvious superelasticity is retained in Ti50.6Pd30Ni19.4 alloy annealed at 400℃ for 18 h, and annealing at higher temperature shows a deterioration of this property. The Ce addition in Ti51Pd28Ni21 alloy significantly delays recrystallization, increases yied strength and elastic modulus, but the superelasticity is poor.

  6. Modeling and Re-Engineering of Azotobacter vinelandii Alginate Lyase to Enhance Its Catalytic Efficiency for Accelerating Biofilm Degradation.

    Directory of Open Access Journals (Sweden)

    Chul Ho Jang

    Full Text Available Alginate is known to prevent elimination of Pseudomonas aeruginosa biofilms. Alginate lyase (AlgL might therefore facilitate treatment of Pseudomonas aeruginosa-infected cystic fibrosis patients. However, the catalytic activity of wild-type AlgL is not sufficiently high. Therefore, molecular modeling and site-directed mutagenesis of AlgL might assist in enzyme engineering for therapeutic development. AlgL, isolated from Azotobacter vinelandii, catalyzes depolymerization of alginate via a β-elimination reaction. AlgL was modeled based on the crystal structure template of Sphingomonas AlgL species A1-III. Based on this computational analysis, AlgL was subjected to site-directed mutagenesis to improve its catalytic activity. The kcat/Km of the K194E mutant showed a nearly 5-fold increase against the acetylated alginate substrate, as compared to the wild-type. Double and triple mutants (K194E/K245D, K245D/K319A, K194E/K245D/E312D, and K194E/K245D/K319A were also prepared. The most potent mutant was observed to be K194E/K245D/K319A, which has a 10-fold improved kcat value (against acetylated alginate compared to the wild-type enzyme. The antibiofilm effect of both AlgL forms was identified in combination with piperacillin/tazobactam (PT and the disruption effect was significantly higher in mutant AlgL combined with PT than wild-type AlgL. However, for both the wild-type and K194E/K245D/K319A mutant, the use of the AlgL enzyme alone did not show significant antibiofilm effect.

  7. Genomic polymorphism and protein changes of soybean mutant induced by space environment

    Science.gov (United States)

    He, J.; Gao, Y.; Sun, Y.

    Soybean 194 4126 of excellent agricultural qualities such as high yield and rounder and wider leaf was selected in six generation after abroad recoverable satellite 15 days in 1996 from Soybean 72163 featured with long-leaf white-blossom grey-hair and infinitude-poding To explore the mechanisms of plant mutation induced by space environment we have experimented at genome and proteome level on Soybean 194 4126 and its control Soybean 72163 Amplified Fragment Length Polymorphism AFLP was used to identify mutated sits and the result shows that 36 polymorphic bands varying between 100 and 900 bp in 2022 DNA bands varying between 100 and 1500 bp have been amplified out of 64 pairs of primer combinations between mutant Soybean 194 4126 and the control plant So the mutation degree of DNA is 3 56 The protein two-dimensional electrophoresis 2-DE and peptide mass fingerprint PMF assays were used to investigate the difference of proteins in fruits and leaves between Soybean 194 4126 and its control Results indicate that 62 protein dots specially appear in Soybean 72163 and 39 dots specially in the mutant Soybean 194 4126 by image analysis software PDQuest in the 2-DE maps of soybean seeds Using PMF assay and protein data-base searching to investigate two distinct protein dots we found that the protein specially expressed in the seed of mutant Soybean 194 4126 may be Dehydrin and the other protein specially expressed in the seed of the control Soybean 72163 may be maturation-associated protein MAT1 Because Dehydrin and MAT1 are

  8. Modeling and Re-Engineering of Azotobacter vinelandii Alginate Lyase to Enhance Its Catalytic Efficiency for Accelerating Biofilm Degradation

    Science.gov (United States)

    Jang, Chul Ho; Piao, Yu Lan; Huang, Xiaoqin; Yoon, Eun Jeong; Park, So Hee; Lee, Kyoung; Zhan, Chang-Guo; Cho, Hoon

    2016-01-01

    Alginate is known to prevent elimination of Pseudomonas aeruginosa biofilms. Alginate lyase (AlgL) might therefore facilitate treatment of Pseudomonas aeruginosa-infected cystic fibrosis patients. However, the catalytic activity of wild-type AlgL is not sufficiently high. Therefore, molecular modeling and site-directed mutagenesis of AlgL might assist in enzyme engineering for therapeutic development. AlgL, isolated from Azotobacter vinelandii, catalyzes depolymerization of alginate via a β-elimination reaction. AlgL was modeled based on the crystal structure template of Sphingomonas AlgL species A1-III. Based on this computational analysis, AlgL was subjected to site-directed mutagenesis to improve its catalytic activity. The kcat/Km of the K194E mutant showed a nearly 5-fold increase against the acetylated alginate substrate, as compared to the wild-type. Double and triple mutants (K194E/K245D, K245D/K319A, K194E/K245D/E312D, and K194E/K245D/K319A) were also prepared. The most potent mutant was observed to be K194E/K245D/K319A, which has a 10-fold improved kcat value (against acetylated alginate) compared to the wild-type enzyme. The antibiofilm effect of both AlgL forms was identified in combination with piperacillin/tazobactam (PT) and the disruption effect was significantly higher in mutant AlgL combined with PT than wild-type AlgL. However, for both the wild-type and K194E/K245D/K319A mutant, the use of the AlgL enzyme alone did not show significant antibiofilm effect. PMID:27253324

  9. VISUAL ACUITY AND CLINICAL REFRACTION FOLLOWING IMPLANTATION OF VARIOUS MULTIFOCAL INTRAOCULAR LENSES

    OpenAIRE

    N. N. Temirov; N. E. Temirov

    2015-01-01

    Aim. To analyze visual acuity, clinical refraction, and defocusing tolerance after the implantation of monofocal IOL with rotational asymmetric optic (Lentis Mplus 313 MF) compared with Acrysof ReSTOR SN6AD1.Materials and methods. Phacoemulsification was performed in a total of 194 patients (288 eyes), i.e., 144 patients (188 eyes) with cataract and 50 patients (100 eyes) with presbyopia and high ametropia. The patients were divided into two groups. Study group included 132 patients (194 eyes...

  10. Acute Toxicity and Neurotoxicity of Chlorpyrifos in Black Tiger Shrimp, Penaeus monodon

    OpenAIRE

    Tassanee Eamkamon; Sirawut Klinbunga; Kumthorn Thirakhupt; Piamsak Menasveta; Narongsak Puanglarp

    2012-01-01

    Acute toxicity and neurotoxicity of chlorpyrifos were determined in black tiger shrimp, P. monodon. LC50 values after 24 to 96 h of exposure were between 149.55 and 59.16 nmol/L. To determine the neurotoxicity of chlorpyrifos, the inhibition of acetylcholinesterase was monitored in the gill of the shrimps exposed to lethal (0.019, 0.194, and 1.942 µmol/L) and sub-lethal (0.019, 0.194, and 1.942 nmol/L) concentrations of chlorpyrifos. In lethal dose exposure, the AChE activities observed in sh...

  11. Atomic force microscopy-coupled microcoils for cellular-scale nuclear magnetic resonance spectroscopy

    Science.gov (United States)

    Mousoulis, Charilaos; Maleki, Teimour; Ziaie, Babak; Neu, Corey P.

    2013-04-01

    We present the coupling of atomic force microscopy (AFM) and nuclear magnetic resonance (NMR) technologies to enable topographical, mechanical, and chemical profiling of biological samples. Here, we fabricate and perform proof-of-concept testing of radiofrequency planar microcoils on commercial AFM cantilevers. The sensitive region of the coil was estimated to cover an approximate volume of 19.4 × 103 μm3 (19.4 pl). Functionality of the spectroscopic module of the prototype device is illustrated through the detection of 1Η resonance in deionized water. The acquired spectra depict combined NMR capability with AFM that may ultimately enable biophysical and biochemical studies at the single cell level.

  12. Formation and decay of neutron—deficient nuclei Po and Pb

    Institute of Scientific and Technical Information of China (English)

    ChenXue-Shi; AhmadI; 等

    1998-01-01

    A study of α-decay for &192,194Po and 188.190Pb was performed in the reaction of 36Ar on 160Dy at 176MeV,The formation cross sction was obtained to be 5.0±0.2μb for 192Po and 11.6±0.3ub for 194Po.The resulting reduced αwidth δ2 was 38(5)keV for 188Pb and 25(3)keV for 190Pb,which further confirmed the magic characteristics for neutron-deficient nuclei of Z=82.

  13. Study of Neutron-Deficient $^{202-205}$Fr Isotopes with Collinear Resonance Ionization Spectroscopy

    CERN Document Server

    De Schepper, Stijn; Cocolios, Thomas; Budincevic, Ivan

    The scope of this master’s thesis is the study of neutron-deficient $^{202−205}$Fr isotopes. These isotopes are inside the neutron-deficient lead region, a region that has shown evidence of shape coexistence. For this thesis, this discussion is limited to the phenomenon where a low lying excited state has a different shape than the ground state. Shape coexistence is caused by intruder states. These are single-particle Shell Model states that are perturbed in energy due to the interaction with a deformed core. In the neutron-deficient lead region the main proton intruder orbit is the 3s$_{1/2}$orbit. When going towards more neutron-deficient isotopes, deformation increases. The $\\pi3s_{1/2}$orbit will rise in energy and will eventually become the ground state in odd- A bismuth (Z=83) isotopes. It is also observed in odd-A astatine (Z=85) isotopes, already in less neutron-deficient nuclei. The same phenomenon is expected to be present francium (Z=87) isotopes already at $^{199}$Fr. Although it is currently ...

  14. The biokinetics of alpha-particle emitting radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, D.M. [School of Chemistry, Cardiff Univ., Cardiff (United Kingdom); Duffield, J.R. [Faculty of Applied Sciences, Univ. of the West of England, Bristol (United Kingdom)

    2005-07-01

    The past two decades have seen wide interest in the application of alpha-particle emitting radionuclides for targeted endoradiotherapy and a large number of compounds labeled with {sup 211}At (T{sup 1}/{sub 2} 7.21 h), {sup 212}Bi (T{sup 1}/{sub 2} 1 h) or {sup 213}Bi (T{sup 1}/{sub 2} 0.78 h) have been studied. Knowledge of the biokinetic behaviour of such agents is important both for their optimal clinical exploitation and for general radiological protection purposes. Animal studies of the distribution and retention of {sup 211}At compounds, including ionic astatide, substituted aromatic compounds and labelled monoclonal antibodies, have provided new information on the biochemistry of astatine. With respect the thyroid gland the uptake of the astatide ion has been shown to be very much lower than that of the iodide ion. Less information is available for {sup 212}Bi-labelled radiopharmaceuticals. The available data for both {sup 211}At and {sup 212}Bi radiopharmaceuticals are reviewed. Cautious generic biokinetic models for inorganic and simple organic compounds of {sup 211}At and {sup 212}Bi; for [{sup 211}At]-, and [{sup 212}Bi]-biphosphonates and for [{sup 211}At]-, and [{sup 212}Bi]-monoclonal antibodies, are proposed for use in general radiological protection when compound-specific data are not available. (orig.)

  15. Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with {sup 211}At-EGF

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, Aasa Liljegren; Orlova, Anna; Gedda, Lars; Tolmachev, Vladimir; Carlsson, Joergen [Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala (Sweden); Almqvist, Ylva [Division of Radiology, Uppsala University, Uppsala (Sweden); Blomquist, Erik [Division of Oncology, Uppsala University, Uppsala (Sweden); Jensen, Holger J. [Department of Clinical Physiology and Nuclear Medicine, PET and Cyclotron Unit, Rigshospitalet, Copenhagen (Denmark)

    2003-10-01

    The EGFR-TKI (epidermal growth factor receptor tyrosine kinase inhibitor) gefitinib ['Iressa' (trademark of the AstraZeneca group of companies), ZD1839] increases the cellular uptake of radiolabelled epidermal growth factor (EGF). We investigated gefitinib treatment combined with astatine-211 EGF targeting in vitro using two cell lines expressing high levels of EGFR: A431 (sensitive to gefitinib) and U343MGaCl2:1 (resistant to gefitinib). In both cell lines, the uptake of {sup 211}At-EGF was markedly increased by concomitant treatment with gefitinib. Survival was investigated using both a clonogenic survival assay and a cell growth assay. Combined gefitinib and {sup 211}At-EGF treatment reduced the survival of U343 cells 3.5-fold compared with {sup 211}At-EGF alone. In A431 cells, {sup 211}At-EGF treatment resulted in very low survival, but combined treatment with gefitinib increased the survival by about 20-fold. These results indicate that combined treatment with gefitinib might increase the effect of ligand-mediated radionuclide therapy in gefitinib-resistant tumours and decrease the effect of such therapy in gefitinib-sensitive tumours. (orig.)

  16. Alpha particle emitters in medicine

    International Nuclear Information System (INIS)

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 (211At) and natural bismuth-212 (212Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 (223Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs

  17. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  18. Development of Reagents for Application of At-211 to Targeted Radionuclide Therapy of Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D. Scott

    2011-12-23

    This grant covered only a period of 4 months as the major portion of the award was returned to DOE due to an award of funding from NIH that covered the same research objectives. A letter regarding the termination of the research is attached as the last page of the Final Report. The research conducted was limited due to the short period of this grant, but the results obtained in that period are outlined in the Final Report. The studies addressed in the research effort were directed at a problem that is of critical importance to the in vivo application of the alpha-particle emitting radionuclide At-211. That problem, low in vivo stability of many astatinated molecules, severely limits the use of At-211 in therapeutic applications. The advances sought in the studies were expected to expand the types of biomolecules that can be used as carriers of At-211, and provide improved in vivo targeting of the radiation dose compared with the dose delivered to normal tissue.

  19. Tumor immunotargeting using innovative radionuclides.

    Science.gov (United States)

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  20. SPECT assay of radiolabeled monoclonal antibodies. Progress report, September 1, 1992--August 24, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1993-08-20

    The overall goal of this project is to improve the effectiveness of single photon emission computed tomography (SPECT) to image and quantify radiolabeled monoclonal antibodies. During the past year, we have made significant progress toward this goal, and this report summarizes that work. Our efforts have been mainly directed along three fronts. First, we have developed and tested new reconstruction methods including three-dimensional iterative algorithms that model non-uniform attenuation and distance-dependent detector response. Both fan beam and parallel beam collimator geometries have been modeled and novel ways of improving the efficiency of the computationally intensive methods have been introduced. Second, an ultra-high resolution, small field-of-view pinhole collimator has been constructed and evaluated. Reconstructed spatial resolution of 1 to 3 mm (FWHM) has been achieved in phantom scans with a useful field-of-view of 9 to 10 cm. Finally, we have investigated the ability of SPECT to image and quantify astatine-211 distributions. Reconstructed images of phantom data demonstrated quantitative accuracy to within 10% with proper attenuation and scatter compensation.

  1. Silver impregnated nanoparticles of titanium dioxide as carriers for {sup 211}At

    Energy Technology Data Exchange (ETDEWEB)

    Cedrowska, Edyta; Lyczko, Monika; Piotrowska, Agata; Bilewicz, Aleksander [Institute of Nuclear Chemistry and Technology, Warsaw (Poland); Stolarz, Anna; Trcinska, Agnieszka [Warsaw Univ. (Poland). Heavy Ion Lab.; Szkliniarz, Katarzyna [Silesia Univ. Katowice (Poland). Inst. of Physics; Was, Bogdan [Polish Academy of Science, Cracow (Poland). Inst. of Nuclear Physics

    2016-08-01

    The {sup 211}At radioisotope exhibits very attractive nuclear properties for application in radionuclide therapy. Unfortunately use of {sup 211}At is limited, because astatine as the heaviest halogen forms weak bond with carbon atoms in the biomolecules which makes {sup 211}At bioconjugates unstable in physiological conditions. In our work we propose a new solution for binding of {sup 211}At which consists of using nanoparticles of titanium dioxide modified with silver atoms as carriers for {sup 211}At. Ag{sup +} cations have been absorbed on the nanometer-sized TiO{sub 2} particles (15 and 32 nm) through ion exchange process and were reduced in Tollens' reaction. The obtained TiO{sub 2}-Ag nanoparticles were labeled with {sup 211}At. It was found that labeling yields were almost quantitative under reducing conditions, while under oxidizing conditions they dropped to about 80%. The labeled nanoparticles exhibited very high stability in physiological salt, PBS buffer, solutions of peptides (0.001 M cysteine, 0.001 M glutathione) and in human blood serum. To make TiO{sub 2}/Ag nanoparticles well dispersed in water and biocompatible their surface was modified with a silane coupling agent containing poly(ethyleneglycol) molecules. The developed functionalization approach will allow us to attach biomolecules to the TiO{sub 2}/Ag surface.

  2. Nuclear and chemical data for life sciences

    International Nuclear Information System (INIS)

    Use of reactor produced radionuclides is popular in life sciences. However, cyclotron production of proton rich radionuclides are being more focused in recent times. These radionuclides have already gained attention in various fields, including life sciences, provided they are obtained in pure form. This article is a representative brief of our contributions in generating nuclear data for the production of proton rich radionuclides of terbium, astatine, technetium, ruthenium, cadmium, niobium, zirconium, rhenium, etc., which may have application in clinical, biological, agriculture studies or in basic research. The chemical data required to separate the product isotopes from the corresponding target matrix have been presented along with a few propositions of radiopharmaceuticals. It also emphasizes on the development of simple empirical technique, based on the nuclear reaction model analysis, to generate reliable nuclear data for the estimation of yield and angular distribution of emitted neutrons and light charged particles from light as well as heavy ion induced reactions on thick stopping targets. These data bear utmost important in radiation dosimetry. (author)

  3. Studies of Stable Octupole Deformations in the Radium Region

    CERN Multimedia

    2002-01-01

    The purpose of the present project is to locate and identify states in the atomic nuclei possessing stable pearshaped octupole deformation. Such states, formally related to the structures known in molecular physics, manifest themselves as families of parity doublets in odd nuclei.\\\\ \\\\ The best possibilities for observing stable octupole deformations are offered in the Ra-region. Both theoretical calculations and experimental indications support such expectations. Such indications are the non-observation of two-phonon octupole vibrational states in the ISOLDE studies of the even-even radium nuclei, and the reversed sign of the decoupling factor of the ground state band in |2|2|5Ra observed in the single-neutron transfer reactions. In order to establish the predicted strong E1 and E3-transitions between the parity doublets in odd nuclei with stable octupole deformations it is proposed to study conversion electrons in odd-mass francium radium and radon isotopes following the @b-decay of francium and astatine. \\...

  4. Alpha particle emitters in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R.

    1989-09-01

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

  5. Nature, socioeconomics and adaptation to natural disasters: new evidence from floods

    OpenAIRE

    Ferreira, Susana; Hamilton, Kirk; Vincent, Jeffrey R.

    2011-01-01

    The authors analyze the determinants of fatalities in 2,194 large flood events in 108 countries between 1985 and 2008. Given that socioeconomic factors can affect mortality right in the aftermath of a flood, but also indirectly by influencing flood frequency and magnitude, they distinguish between direct and indirect effects of development on flood mortality. The authors find that income i...

  6. Data of evolutionary structure change: 1YLJA-3BLMA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1YLJA-3BLMA 1YLJ 3BLM A A QTSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDE... 194 LEU CA 258 LEU CA 327 ASN CA 247 3BLM... A 3BLMA LLEQVPYNKL... CA 338 THR CA 465 THR CA 490 3BLM... A 3BLMA KSGQ

  7. Intergenerational Contact and Mediators Impact Ambivalence towards Future Selves

    Science.gov (United States)

    Jarrott, Shannon E.; Savla, Jyoti

    2016-01-01

    Intergenerational contact can promote positive attitudes towards elders. However, contact with older adults often fosters multiple stereotypes, which may contribute to ambivalence about aging and poorer health in late life. Online survey data from 457 young adults (M age = 19.4 years; 74% female) were used to explore the relationship between…

  8. A Study of Prospective Turkish Science Teachers' Knowledge at the Popular Biotechnological Issues

    Science.gov (United States)

    Darcin, Emine Selcen; Turkmen, Lutfullah

    2006-01-01

    The purpose of this study was to determine the knowledge level of popular biotechnological issues of prospective Turkish science teachers. A questionnaire was administered during 2005-2006 academic year to 194 students in the Department of Science Education of a university in Turkey. The questionnaire covered six biotechnological issues such as…

  9. AcEST: DK957319 [AcEST

    Lifescience Database Archive (English)

    Full Text Available EVYDLEQDRWTKLPSLRRA 203 +W+ VASM + R FAC + P EVYD DRW +LP++ R Sbjct: 144 QWKMVASMRTPRTHFACTS...TIGHSRCV---DVFDPLKGQW 323 +D + +W + S+R R + GK+YV GR+ + HSR + +V+DP+ +W Sbjct: 138 FDPFKKQWKMVASMRTPRTHFAC...TSVSGKVYVAGGRN---LTHSRGIPSAEVYDPVADRW 194 Query: 324 EE--------------AKNGCMMVLAHAIV

  10. Differences in overweight and obesity among children from migrant and native origin : The role of physical activity, dietary intake, and sleep duration

    NARCIS (Netherlands)

    L.J.W. Labree (Wim); D. van de Mheen (Dike); M.P.M.H. Rutten-van Mölken (Maureen); G. Rodenburg (Gerda); G.T. Koopmans (Gerrit); M.M.E. Foets (Marleen)

    2015-01-01

    textabstractA cross-sectional survey was performed to examine to what degree differences in overweight and obesity between native Dutch and migrant primary school children could be explained by differences in physical activity, dietary intake, and sleep duration among these children. Subjects (n=194

  11. Teachers' Attitudes toward the Integration of Pupils with Intellectual Disabilities.

    Science.gov (United States)

    Kis-Glavas, Lelia; And Others

    This study examined the attitudes of 194 teachers in 17 regular primary schools in the city of Zagreb (Croatia) and the surrounding area about the integration of children with intellectual or other developmental disabilities. In addition to providing demographic data, the teachers completed a 21-item questionnaire with questions that addressed:…

  12. Developmental Dynamics of Math Performance From Preschool to Grade 2

    Science.gov (United States)

    Aunola, Kaisa; Leskinen, Esko; Lerkkanen, Marja-Kristiina; Nurmi, Jari-Erik

    2004-01-01

    This study investigated the developmental dynamics of mathematical performance during children's transition from preschool to Grade 2 and the cognitive antecedents of this development. 194 Finnish children were examined 6 times according to their math performance, twice during each year across a 3-year period. Cognitive antecedents, that is,…

  13. The Effects on Students' Conceptual Understanding of Electric Circuits of Introducing Virtual Manipulatives within a Physical Manipulatives-Oriented Curriculum

    Science.gov (United States)

    Zacharia, Zacharias C.; de Jong, Ton

    2014-01-01

    This study investigates whether Virtual Manipulatives (VM) within a Physical Manipulatives (PM)-oriented curriculum affect conceptual understanding of electric circuits and related experimentation processes. A pre-post comparison study randomly assigned 194 undergraduates in an introductory physics course to one of five conditions: three…

  14. Xinjiang:Cotton Yield Down 21.3%

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Under the impact of policy adjustment and market recession, the larg-est cotton region Xinjiang reported coverage of 20.156 million mu, down 19.4%. The yeild is estimated to be 2.3746 million tons, down 21.3%

  15. Motives for Dissertation Research at the Intersection between Rural Education and Curriculum and Instruction

    Science.gov (United States)

    Howley, Craig B.; Howley, Aimee; Yahn, Jacqueline

    2014-01-01

    Dissertation literature focusing on issues of curriculum and instruction (C&I) in rural schools has substantially increased since 1987. We located 580 possibly rural C&I dissertations and subsequently identifi ed 194 as probably rural; of these we were able to obtain digital copies of 188 full-length studies. Our purpose was to…

  16. Monetka iz-za morja / Josef Kats

    Index Scriptorium Estoniae

    Kats, Josef, 1977-

    2005-01-01

    Eesti Panga president Andres Lipstok ja Soome Rahapaja OY tegevdirektor Raimo Makkonen allkirjastasid 19. detsembril mündivermimise lepingu, mille kohaselt vermib Eesti euromündid Rahapaja OY. Ettevõte vermib Eestile 194 miljonit euromünti

  17. Parental Behaviors during Family Interactions Predict Changes in Depression and Anxiety Symptoms during Adolescence

    Science.gov (United States)

    Schwartz, Orli S.; Dudgeon, Paul; Sheeber, Lisa B.; Yap, Marie B. H.; Simmons, Julian G.; Allen, Nicholas B.

    2012-01-01

    This study investigated the prospective, longitudinal relations between parental behaviors observed during parent-adolescent interactions, and the development of depression and anxiety symptoms in a community-based sample of 194 adolescents. Positive and negative parental behaviors were examined, with negative behaviors operationalized to…

  18. Perceptions of Domestic Violence: The Effects of Domestic Violence Myths, Victim's Relationship with Her Abuser, and the Decision to Return to Her Abuser

    Science.gov (United States)

    Yamawaki, Niwako; Ochoa-Shipp, Monica; Pulsipher, Craig; Harlos, Andrew; Swindler, Scott

    2012-01-01

    Researchers in this study examined the attitudes toward domestic violence, the victim, and her perpetrator. A total of 194 participants were randomly assigned to one of 4 hypothetical scenarios to evaluate how observers' perceptions were influenced by their own sex and myths about domestic violence, by the victim's decision to return to the…

  19. How Providing Mentoring Relates to Career Success and Organizational Commitment: A Study in the General Managerial Population

    Science.gov (United States)

    Bozionelos, Nikos; Bozionelos, Giorgos; Kostopoulos, Konstantinos; Polychroniou, Panagiotis

    2011-01-01

    Purpose: This study aims to investigate the relationship of mentoring provided with career success and organizational commitment in the general managerial population. Design/methodology/approach: Participants were 194 native British who were employed in a variety of jobs, professions and industries in the United Kingdom. Findings: Mentoring…

  20. Electrocardiographic precordial ST-segment deviations and the risk of cardiovascular death

    DEFF Research Database (Denmark)

    Rasmussen, Peter Vibe; Nielsen, Jonas Bille; Pietersen, Adrian;

    2014-01-01

    computerized analysis of ECGs from 285 194 persons, we evaluated the association between precordial ST-segment deviations and the risk of CVD. All data on medication, comorbidity, and outcomes were retrieved from Danish registries. After a median follow-up period of 5.8 years, there were 6679 cardiovascular...

  1. Attitudes and Self-Efficacy of Pre-Service Teachers towards Inclusion in Pakistan

    Science.gov (United States)

    Sharma, Umesh; Shaukat, Sadia; Furlonger, Brett

    2015-01-01

    This study sought to determine the attitudes and teaching self-efficacy of pre-service teachers towards the inclusion of students with disabilities into regular classrooms. A questionnaire was administered to 194 pre-service Pakistani teachers (male 73, female 121) enrolled in a 1-year teacher education programme at a government university in…

  2. Assessment of menstrual characteristics among nulliparous female consumers of carbonated soft drinks

    Directory of Open Access Journals (Sweden)

    Ologhaguo M. Adienbo

    2016-01-01

    Conclusions: This study has shown that consumption of soft drinks during menstruation could alter menstrual characteristics in nulliparous females by increasing the menstrual flow, menstrual pain and menstrual duration. [Int J Reprod Contracept Obstet Gynecol 2016; 5(1.000: 194-197

  3. Value Added: The Economic Impact of Public Universities.

    Science.gov (United States)

    National Association of State Universities and Land Grant Colleges, Washington, DC.

    This monograph reports the results of a survey of the economic impact on state and local economies of the 194 member institutions of the National Association of State Universities and Land-Grant Colleges. Analysis of responses (from 111 institutions) is reported in text and graphs. An introductory section notes that the recent emphasis on cutting…

  4. Co-Rumination Cultivates Anxiety: A Genetically Informed Study of Friend Influence during Early Adolescence

    Science.gov (United States)

    Dirghangi, Shrija; Kahn, Gilly; Laursen, Brett; Brendgen, Mara; Vitaro, Frank; Dionne, Ginette; Boivin, Michel

    2015-01-01

    This study tested 2 related hypotheses. The first holds that high co-rumination anticipates heightened internalizing problems. The second holds that positive relationships with friends exacerbate the risk for internalizing problems arising from co-rumination. A sample of MZ twins followed from birth (194 girls and 170 boys) completed (a)…

  5. Predictors of Academic Procrastination and University Life Satisfaction among Turkish Sport Schools Students

    Science.gov (United States)

    Ocal, Kubilay

    2016-01-01

    The purpose of this study was to examine the role of burnout, academic self-efficacy and academic success in predicting procrastination and university life satisfaction among sports schools students. The study sample comprised of 224 participants aged from 18 to 30 years with a mean age of 21.71 (SD = 1.94) who were attending various departments…

  6. Reviews

    NARCIS (Netherlands)

    NN,

    1982-01-01

    This book is designed as a practical guide for the identification of fossil and extant woods with the aid of a marginally perforated card key, based on the ones devised by Clarke and perfected in the well-known Hardwood and Softwood keys published by the Princes Risborough Laboratory in 1961 and 194

  7. Middle-School Homework Management: More than Just Gender and Family Involvement

    Science.gov (United States)

    Xu, Jianzhong

    2007-01-01

    The article links student and family characteristics, along with homework characteristics and homework purposes, to homework management as reported by 194 middle-school students in Grades 5-6. The results revealed that homework management was not related to grade level, amount of parental education, time spent on homework, or extrinsic reasons for…

  8. Injury Patterns In Low Intensity Conflict

    Directory of Open Access Journals (Sweden)

    V Saraswat

    2009-01-01

    Most common mode of injury was Gunshot wound (41.4%, followed by splinter injuries (39.2% and Road traffic accident(RTA (19.4%. Overall mortality was 3.8% and inpatient mortality of 1.4%. Head and neck injuries were leading cause of death followed by thoracic injuries.

  9. Insects of terrestrial origin over Indian Ocean during north-east monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    Pathak, S.C.; Kulshrestha, V.; Choubey, A.K.; Parulekar, A.H.

    ,217 airborne insects belonging to 7 orders, 53 families and 194 species were collected from 57 sampling stations, over 33 days. Hemiptera was the order with the highest number of insects (1,450), followed by Diptera (1,111), Hymenoptera (510) and Coleoptera...

  10. File list: InP.Liv.10.AllAg.Liver_tumor [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Liv.10.AllAg.Liver_tumor mm9 Input control Liver Liver tumor SRX1008193,SRX1008...194 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Liv.10.AllAg.Liver_tumor.bed ...

  11. InterProScan Result: FS789827 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS789827 FS789827_3_ORF1 471A90174D851C20 PANTHER PTHR23300 SELENIUM-BINDING PROTEIN 9e-194 T IPR008826 Sele...nium-binding protein Molecular Function: selenium binding (GO:0008430) ...

  12. Self-Regulation of Physical Education Teacher Education Students' Attitudes towards Exercise and Diet

    Science.gov (United States)

    Wilkinson, Carol; Prusak, Keven

    2013-01-01

    The purpose of this study was to assess differences in self-regulation of attitudes towards engaging in exercise and eating a healthy diet between physical education teacher education (PETE) students and general education (GE) students, and between male students and female students. Participants were university students (n = 194) at a university…

  13. Severity Differences among Self-Assessors, Peer-Assessors, and Teacher Assessors Rating EFL Essays

    Science.gov (United States)

    Esfandiari, Rajab; Myford, Carol M.

    2013-01-01

    We compared three assessor types (self-assessors, peer-assessors, and teacher assessors) to determine whether they differed in the levels of severity they exercised when rating essays. We analyzed the ratings of 194 assessors who evaluated 188 essays that students enrolled in two state-run universities in Iran wrote. The assessors employed a…

  14. Profiles of Motivated Self-Regulation in College Computer Science Courses: Differences in Major versus Required Non-Major Courses

    Science.gov (United States)

    Shell, Duane F.; Soh, Leen-Kiat

    2013-01-01

    The goal of the present study was to utilize a profiling approach to understand differences in motivation and strategic self-regulation among post-secondary STEM students in major versus required non-major computer science courses. Participants were 233 students from required introductory computer science courses (194 men; 35 women; 4 unknown) at…

  15. AcEST: BP912286 [AcEST

    Lifescience Database Archive (English)

    Full Text Available OS=Homo sapiens GN=SRCAP PE... 72 3e-12 sp|Q9NDJ2|DOM_DROME Helicase domino OS=Drosophila melanogaster G... ...VGQTE+YS +L++ Sbjct: 194 IASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQ 249 >sp|Q9NDJ2|DOM_DROME Helicase domino

  16. EST Table: CK510757 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available 969652.1| PREDICTED: similar to high density lipoprotien binding protein / vigilin [Tribolium castaneum] BY919895 swd ... ...CK510757 rswdd0_006585.y1 10/09/29 51 %/164 aa ref|XP_969652.1| PREDICTED: similar to high density lipoproti...en binding protein / vigilin [Tribolium castaneum] 10/08/30 38 %/194 aa FBpp0234312

  17. Linguo-Intercultural Sensitivity and Its Predictors in EFL in a Bosnian Sample

    Science.gov (United States)

    Aydogan, Hakan; Akbarov, Azamat

    2015-01-01

    In this article, the predictive power of five variables relevant for Linguo-intercultural sensitivity (flexibility) is examined. Communication aspect of intercultural interactions, specifically, the role of English as an international language are emphasized. Attitudes Towards English and Its Usage Scale (ATEUS) was applied to 194 students who…

  18. The 1984 Literacy Campaign in the People's Democratic Republic of Yemen. A Case Study. Notes, Comments...No. 183.

    Science.gov (United States)

    Fara, Mohammed Saeed; Fisher, Nigel

    In 1984, the People's Democratic Republic of Yemen undertook a nationwide literacy campaign, which mobilized the entire nation in an effort to reach an estimated 194,000 illiterate people, 77 percent of them women. The campaign plan demanded the full and active participation of formal school teachers and students at secondary level and above as…

  19. Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

    DEFF Research Database (Denmark)

    Bodenlenz, Manfred; Höfferer, Christian; Magnes, Christoph;

    2012-01-01

    OFM sampling was performed for 25 h from each site on day 1 and day 8. Patients were mobile as dOFM probes were operated by a novel light-weight push-pull pump. Ultrasound was used to verify intradermal probe placement, cap-LC-MS/MS for BCT194 and ELISA for TNFα analysis. RESULTS: dOFM was well tolerated...

  20. Effectiveness of an intervention to reduce sickness absence in patients with emotional distress or minor mental disorders: a randomized controlled effectiveness trial.

    NARCIS (Netherlands)

    Brouwers, E.P.M.; Tiemens, B.G.; Terluin, B.; Verhaak, P.F.M.

    2006-01-01

    OBJECTIVE: The purpose of this study was to evaluate the effectiveness of an activating intervention designed to reduce sick leave duration in patients with emotional distress or minor mental disorders. METHOD: In a 1.5-year randomized controlled trial, 194 patients with minor mental disorders recei

  1. AcEST: BP912488 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 3|B5AH23_9ROSI Ribosomal protein L33 OS=Gonystylus banca... 79 2e-13 tr|B3IWG9|B3IWG9_TAKLE Ribosomal protei...23_9ROSI Ribosomal protein L33 OS=Gonystylus bancanus GN=rpl33 PE=4 SV=1 Length = 66 Score = 79.3 bits (194)

  2. Non-weight-bearing status compromises the functional level up to 1 yr after hip fracture surgery

    DEFF Research Database (Denmark)

    Ariza-Vega, Patrocinio; Jiménez-Moleón, José Juan; Kristensen, Morten Tange

    2014-01-01

    OBJECTIVE: The aim of this study was to examine the influence of weight-bearing (WB) status after hip fracture surgery on 1-yr functional outcome. DESIGN: This was a prospective cohort study, carried out in a public acute hospital trauma service. The 194 patients (36 men and 158 women), with a me...

  3. Ecology of phytoplankton from Dharmatar Creek, west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Tiwari, L.R.; Nair, V.R.

    was vertically mixed except during the monsoon period and nutrients never became a limiting factore for phytoplankton production. Concentration of chlorophyll a and phaeophytin were fairly high, (av. 1.94 and 1.89 mg m sup(-3) respectively). A total of 58 general...

  4. The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1

    DEFF Research Database (Denmark)

    Hanssen-Bauer, Audun; Solvang-Garten, Karin; Gilljam, Karin Margaretha;

    2012-01-01

    most common amino acid variants of XRCC1, Arg194Trp, Arg280His and Arg399Gln, are located within the region comprising the NLS and BRCT1 domains, and these variants may be associated with increased incidence of specific types of cancer. While we could not detect differences in the intra...

  5. 40 CFR 60.4400 - How do I conduct the initial and subsequent performance tests, regarding NOX?

    Science.gov (United States)

    2010-07-01

    ... = NOX emission rate, in lb/MWh 1.194 × 10−7 = conversion constant, in lb/dscf-ppm (NOX)c = average NOX... emission rate in lb/MWh. (2) Sampling traverse points for NOX and (if applicable) diluent gas are to be... units complying with the output based standard, concurrently measure the stack gas flow rate, using...

  6. New developments in nuclear supersymmetry

    CERN Document Server

    Bijker, R; Barea, J

    2009-01-01

    We discuss several new developments in nuclear supersymmetry, in particular the identification of a new supersymmetric quartet of nuclei in the A~190 mass region, consisting of the 192,193 Os and 193,194 Ir nuclei, and a study of correlations between different transfer reactions.

  7. Aggression in Dating Relationships Compared by Country of Origin

    Science.gov (United States)

    Seligowski, Antonia; West, Doe

    2009-01-01

    Aims: The purpose of this study was to analyze prevalence levels of aggression in dating relationships and to compare this by country of origin. The study also seeks more understanding of the violence experienced by men in these countries. Method: A convenience sample was used; study participants were 194 females and 168 males ranging in age from…

  8. Gclust Server: 125000 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available lightly similar to metyltransfrases 1 1.00e-99 0.0 0.0 0.0 0.0 3.23 0.0 Show 125000 Cluster ID 125000 Sequen...2) Sequence length 194 Representative annotation putative protein, slightly similar to metyltransfrases

  9. On some Chiroptera from Greece

    NARCIS (Netherlands)

    Laar, van Vincent; Daan, Serge

    1964-01-01

    On a trip to Greece between the 25th April and the 25th July 1963, the authors collected (on the mainland and some islands in the Aegean) insects, amphibians and reptiles as well as 194 mammals. Among the mammals, mainly rodents and insectivores, there were also 27 bats, belonging to five species. A

  10. AcEST: DK960561 [AcEST

    Lifescience Database Archive (English)

    Full Text Available =Popul... 220 7e-56 tr|Q94KH9|Q94KH9_AVIMR Aluminium induced protein OS=Avicennia ma... 218 2e-55 tr|Q6UK15|...5 S A+FPQGC+FS+ Sbjct: 181 KSLASFPQGCFFST 194 >tr|Q94KH9|Q94KH9_AVIMR Aluminium i

  11. Multidrug resistance among different serotypes of clinical Salmonella isolates in Taiwan

    DEFF Research Database (Denmark)

    Lauderdale, T. L.; Aarestrup, Frank Møller; Chen, P. C.;

    2006-01-01

    (41%) and was highly prevalent in Salmonella enterica serotype Typhimurium (72.7%, 176/242) the most common serotype. Additional resistance to trimethoprim was present in 155 (19.4% overall) of the ACSSuT R-type isolates from several serotypes. Reduced susceptibility to fluoroquinolone (FQ...

  12. 76 FR 33367 - Employment and Training Administration Program Year (PY) 2011 Allotments for the Workforce...

    Science.gov (United States)

    2011-06-08

    ... ....... $109,736.00 $98,079.00 ($11,657) -10.60% the Yakama Nation. WA Lummi Indian Business Council....00 $194,755.00 ($390.00) -0.2% the Yakama Nation. WA Lummi Indian Business Council... ....... $107... Allotments for the Workforce Investment Act (WIA), Section 166, Indian and Native American Program...

  13. 30 CFR 253.14 - How do I determine the worst case oil-spill discharge volume?

    Science.gov (United States)

    2010-07-01

    ... discharge volume that you determined under whichever of the following regulations applies: (1) 30 CFR Part... estimate for the first 24 hours. (2) 40 CFR Part 112—Oil Pollution Prevention; or (3) 49 CFR Part 194... discharge volume? 253.14 Section 253.14 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF...

  14. Discovery: Prime Numbers

    Science.gov (United States)

    de Mestre, Neville

    2008-01-01

    Prime numbers are important as the building blocks for the set of all natural numbers, because prime factorisation is an important and useful property of all natural numbers. Students can discover them by using the method known as the Sieve of Eratosthenes, named after the Greek geographer and astronomer who lived from c. 276-194 BC. Eratosthenes…

  15. Association between C reactive protein and coronary heart disease : mendelian randomisation analysis based on individual participant data

    NARCIS (Netherlands)

    Wensley, Frances; Gao, Pei; Burgess, Stephen; Kaptoge, Stephen; Di Angelantonio, Emanuele; Shah, Tina; Engert, James C.; Clarke, Robert; Davey-Smith, George; Nordestgaard, Borge G.; Saleheen, Danish; Samani, Nilesh J.; Sandhu, Manjinder; Anand, Sonia; Pepys, Mark B.; Smeeth, Liam; Whittaker, John; Casas, Juan Pablo; Thompson, Simon G.; Hingorani, Aroon D.; Danesh, John; Eiriksdottir, G.; Harris, T. B.; Launer, L. J.; Gudnason, V.; Folsom, A. R.; Andrews, G.; Ballantyne, C. M.; Samani, N. J.; Hall, A. S.; Braund, P. S.; Balmforth, A. J.; Whincup, P. H.; Morris, R.; Lawlor, D. A.; Lowe, G. D. O.; Timpson, N.; Ebrahim, S.; Ben-Shlomo, Y.; Davey-Smith, G.; Timpson, N.; Nordestgaard, B. G.; Tybjaerg-Hansen, A.; Zacho, J.; Brown, M.; Sandhu, M.; Ricketts, S. L.; Ashford, S.; Lange, L.; Reiner, A.; Cushman, M.; Tracy, R.; Wu, C.; Ge, J.; Zou, Y.; Sun, A.; Hung, J.; McQuillan, B.; Thompson, P.; Beilby, J.; Warrington, N.; Palmer, L. J.; Wanner, C.; Drechsler, C.; Hoffmann, M. M.; Fowkes, F. G. R.; Lowe, G. D. O.; Tzoulaki, I.; Kumari, M.; Miller, M.; Marmot, M.; Onland-Moret, C.; van der Schouw, Y. T.; Boer, J. M.; Wijmenga, C.; Ricketts, S. L.; Ashford, S.; Sandhu, M.; Khaw, K-T; Vasan, R. S.; Schnabel, R. B.; Yamamoto, J. F.; Benjamin, E. J.; Schunkert, H.; Erdmann, J.; Koenig, I. R.; Hengstenberg, C.; Chiodini, B.; Franzosi, M. G.; Pietri, S.; Gori, F.; Rudock, M.; Liu, Y.; Lohman, K.; Harris, T. B.; Humphries, S. E.; Hamsten, A.; Norman, P. E.; Hankey, G. J.; Jamrozik, K.; Palmer, L. J.; Rimm, E. B.; Pai, J. K.; Psaty, B. M.; Heckbert, S. R.; Bis, J. C.; Yusuf, S.; Anand, S.; Engert, J. C.; Xie, C.; Collins, R.; Clarke, R.; Bennett, D.; Kooner, J.; Chambers, J.; Elliott, P.; Maerz, W.; Kleber, M. E.; Boehm, B. O.; Winkelmann, B. R.; Melander, O.; Berglund, G.; Koenig, W.; Thorand, B.; Baumert, J.; Peters, A.; Rimm, E. B.; Manson, J.; Pai, J. K.; Humphries, S. E.; Cooper, J. A.; Talmud, P. J.; Ladenvall, P.; Johansson, L.; Jansson, J-H; Hallmans, G.; Reilly, M. P.; Qu, L.; Li, M.; Rader, D. J.; Watkins, H.; Clarke, R.; Hopewell, J.; Saleheen, D.; Danesh, J.; Frossard, P.; Sattar, N.; Robertson, M.; Shepherd, J.; Schaefer, E.; Hofman, A.; Witteman, J. C. M.; Kardys, I.; Dehghan, A.; de Faire, U.; Bennet, A.; Gigante, B.; Leander, K.; Ben-Shlomo, Y.; Davey-Smith, G.; Timpson, N.; Peters, B.; Maitland-van der Zee, A. H.; de Boer, A.; Klungel, O.; Reiner, A.; Manson, J.; Greenland, P.; Dai, J.; Liu, S.; Brunner, E.; Kivimaki, M.; Marmot, M.; Sattar, N.; O'Reilly, D.; Ford, I.; Packard, C. J.

    2011-01-01

    Objective To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. Design Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries. Participants 194 418 particip

  16. 75 FR 34196 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by EDGX Exchange, Inc...

    Science.gov (United States)

    2010-06-16

    ... Organization's Statement of the Terms of Substance of the Proposed Rule Change EDGX proposes to make changes to...-Regulatory Organization's Statement of the Purpose of, and Statutory Basis for, the Proposed Rule Change 1... Exchange Release No. 61698 (March 12, 2010), 75 FR 13151 (March 18, 2010) (approving File Nos. 10-194...

  17. 75 FR 34189 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by EDGA Exchange, Inc...

    Science.gov (United States)

    2010-06-16

    ... Organization's Statement of the Terms of Substance of the Proposed Rule Change EDGA proposes to make changes to...-Regulatory Organization's Statement of the Purpose of, and Statutory Basis for, the Proposed Rule Change 1... Exchange Release No. 61698 (March 12, 2010), 75 FR 13151 (March 18, 2010) (approving File Nos. 10-194...

  18. 78 FR 72612 - Criteria for the Certification and Recertification of the Waste Isolation Pilot Plant's...

    Science.gov (United States)

    2013-12-03

    ... proposed action does not impose an information collection burden under the provisions of the Paper Reduction Act, 44 U.S.C. 3501 et seq. The Compliance Criteria in 40 CFR part 194 requirements are applicable... Compliance Criteria via rulemaking in July 2004 (69 FR 42571-42583). These new provisions provide...

  19. Designing a Digital Future: Federally Funded Research and Development in Networking and Information Technology. Report to the President and Congress

    Science.gov (United States)

    Executive Office of the President, 2010

    2010-01-01

    This report is prepared by the President's Council of Advisors on Science and Technology (PCAST) acting in its role as the President's Innovation and Technology Advisory Council (PITAC). This report fulfills PCAST's responsibilities under Executive Order 13539 and the High-Performance Computing Act of 1991 (Public Law 102-194) as amended by the…

  20. Retinal layer location of increased retinal thickness in eyes with subclinical and clinical macular edema in diabetes type 2

    DEFF Research Database (Denmark)

    Bandello, Francesco; Tejerina, Amparo Navea; Vujosevic, Stela;

    2015-01-01

    PURPOSE: To identify the retinal layer predominantly affected in eyes with subclinical and clinical macular edema in diabetes type 2. METHODS: A cohort of 194 type 2 diabetic eyes/patients with mild nonproliferative diabetic retinopathy (ETDRS levels 20/35) were examined with Cirrus spectral...

  1. Chlamydia and sudden infant death syndrome. A study of 166 SIDS and 30 control cases

    DEFF Research Database (Denmark)

    Banner, Jytte; Lundemose, A G; Gregersen, M;

    1990-01-01

    Chlamydia inclusions could be demonstrated by an immunofluorescence assay in formalin-fixed lung sections in 32 of 166 cases (19.4%) of Sudden Infant Death Syndrome (SIDS) and in the lungs of only 1 of 30 infants with a known cause of death (3.3%). The difference is statistically significant (P =...

  2. Accuracy of Self-Reported College GPA: Gender-Moderated Differences by Achievement Level and Academic Self-Efficacy

    Science.gov (United States)

    Caskie, Grace I. L.; Sutton, MaryAnn C.; Eckhardt, Amanda G.

    2014-01-01

    Assessments of college academic achievement tend to rely on self-reported GPA values, yet evidence is limited regarding the accuracy of those values. With a sample of 194 undergraduate college students, the present study examined whether accuracy of self-reported GPA differed based on level of academic performance or level of academic…

  3. Peer Assessment without Assessment Criteria

    Science.gov (United States)

    Jones, Ian; Alcock, Lara

    2014-01-01

    Peer assessment typically requires students to judge peers' work against assessment criteria. We tested an alternative approach in which students judged pairs of scripts against one another in the absence of assessment criteria. First year mathematics undergraduates (N?=?194) sat a written test on conceptual understanding of multivariable…

  4. Contact sensitization to 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one (MCI/MI). A European multicentre study

    DEFF Research Database (Denmark)

    Menné, T; Frosch, P J; Veien, Niels;

    1991-01-01

    , formaldehyde, paraben-mix, and MCI/MI. 19.4% of the patients had positive patch tests to nickel, making this the most common allergen. 3% of the patients reacted to 100 ppm MCI/MI, while 2.6% reacted to formaldehyde and 1.1% to parabens. There was great variation in the frequency of MCI/MI sensitivity among...

  5. NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

    Science.gov (United States)

    Dammermann, Werner; Zhang, Bo; Nebel, Merle; Cordiglieri, Chiara; Odoardi, Francesca; Kirchberger, Tanja; Kawakami, Naoto; Dowden, James; Schmid, Frederike; Dornmair, Klaus; Hohenegger, Martin; Flügel, Alexander; Guse, Andreas H.; Potter, Barry V. L.

    2009-01-01

    The nucleotide NAADP was recently discovered as a second messenger involved in the initiation and propagation of Ca2+ signaling in lymphoma T cells, but its impact on primary T cell function is still unknown. An optimized, synthetic, small molecule inhibitor of NAADP action, termed BZ194, was designed and synthesized. BZ194 neither interfered with Ca2+ mobilization by d-myo-inositol 1,4,5-trisphosphate or cyclic ADP-ribose nor with capacitative Ca2+ entry. BZ194 specifically and effectively blocked NAADP-stimulated [3H]ryanodine binding to the purified type 1 ryanodine receptor. Further, in intact T cells, Ca2+ mobilization evoked by NAADP or by formation of the immunological synapse between primary effector T cells and astrocytes was inhibited by BZ194. Downstream events of Ca2+ mobilization, such as nuclear translocation of “nuclear factor of activated T cells” (NFAT), T cell receptor-driven interleukin-2 production, and proliferation in antigen-experienced CD4+ effector T cells, were attenuated by the NAADP antagonist. Taken together, specific inhibition of the NAADP signaling pathway constitutes a way to specifically and effectively modulate T-cell activation and has potential in the therapy of autoimmune diseases. PMID:19541638

  6. Austria uuringu tõlgendus: Eesti on eurotsooni must majandus / Kaja Koovit ; kommenteerinud Maria Alajõe

    Index Scriptorium Estoniae

    Koovit, Kaja, 1968-

    2011-01-01

    Austrias asuva Linzi ülikooli uuringu kohaselt moodustab varimajandus Eesti majandusest kolmandiku. SSE Riga ehk Stockholmi majanduskooli Riias Balti varimajanduse uuringu põhjal võib varimajanduse osakaal Eestis olla 19,4 protsenti. Varimajanduse alal maailma juhtivaks eksperdiks peetava Friedrich Schneideri uuringust. Marje Josingu ja Juhan Partsi hinnanguid. Tabel: Varimajandus

  7. Moderating Effects of Aggression on the Associations between Social Withdrawal Subtypes and Peer Difficulties during Early Adolescence

    Science.gov (United States)

    Bowker, Julie C.; Markovic, Andrea; Cogswell, Alex; Raja, Radhi

    2012-01-01

    Recent research has revealed significant heterogeneity in the peer difficulties associated with social withdrawal subtypes during early adolescence, but little is known about possible sources of that heterogeneity. This study of 194 Indian young adolescents (48% female; 90% Hindu; M age = 13.35 years) evaluated whether the peer adversity related…

  8. Comparison of early complications using regular mesh versus Atramat and reg; Neoflex 25 mesh in inguinal, umbilical and post incisional hernias

    Directory of Open Access Journals (Sweden)

    Juan Jos and eacute; Granados-Romero

    2016-01-01

    Conclusions: Using Atramat and reg; Neoflex 25 mesh demonstrated a significant reduction of complications (recurrence and seroma formation and length of hospital stay (2 days vs 1 day in abdominoplasty after surgery. [Int J Res Med Sci 2016; 4(1.000: 194-197

  9. Corporal Punishment in Tanzania's Schools

    Science.gov (United States)

    Feinstein, Sheryl; Mwahombela, Lucas

    2010-01-01

    The purpose of this survey was to acquire descriptive information regarding corporal punishment in Tanzania's O-level secondary schools. 448 individuals participated in the study: 254 teachers and 194 students, all from government or private secondary schools in the Iringa Region of Tanzania. In addition, 14 students and 14 teachers were…

  10. Ajaleht Pravda ja 40 keisri hullu : "40 kiri" sündis siis, kui teisiti enam ei saanud / Lauri Vahtre

    Index Scriptorium Estoniae

    Vahtre, Lauri, 1960-

    2005-01-01

    Eesti kultuuritegelaste kirjutatud "40 kirjast" 1980. aastal, kus tunti muret Eesti ühiskonna ja kultuuri tuleviku pärast. Artikkel sisaldab kirjale allakirjutanute nimesid. Ilmunud ka rmt.: Vahtre, Lauri. Ajaloo pööripäevad. Tallinn, 2006, lk. 190-194

  11. Whom should one thank for a narrow escape? Lessons drawn from a perilous journey from Vormsi and Noarootsi to Finland in 1796 / Jürgen Beyer

    Index Scriptorium Estoniae

    Beyer, Jürgen, 1965-

    2004-01-01

    Autor analüüsib arhiivimaterjalide ja tekstide erinevusi juhtumitest, kus kaheksa Vormsi ja Noarootsi meest sattusid merel tormi kätte, kuid pääsesid õnnelikult. Lisad lk. 194-195 : Eesti kaart (Andree 1893-96 : 91) ja Haapsalu kihelkond (Mellin 1798 : Der Hapsalsche Kreis)

  12. The role of continuity in residual-based variational multiscale modeling of turbulence

    NARCIS (Netherlands)

    Akkerman, I.; Bazilevs, Y.; Calo, V.M.; Hughes, T.J.R.; Hulshoff, S.

    2007-01-01

    This paper examines the role of continuity of the basis in the computation of turbulent flows. We compare standard finite elements and non-uniform rational B-splines (NURBS) discretizations that are employed in Isogeometric Analysis (Hughes et al. in Comput Methods Appl Mech Eng, 194:4135–4195, 2005

  13. Vitamin B12 status is associated to bone mineral content and bone mineral density in frail elderly women, but not in men

    NARCIS (Netherlands)

    Dhonukshe-Rutten, R.A.M.; Lips, M.; Jong, N.; Chin A Paw, M.J.M.; Hiddink, G.J.; Dusseldorp, van M.; Groot, de C.P.G.M.; Staveren, van W.A.

    2003-01-01

    Subclinical vitamin B-12 deficiency is common in the elderly. Encouraged by early indications, we investigated the plasma vitamin B-12 status in association with bone mineral content (BMC) and bone mineral density (BMD) in frail elderly people. Data of 194 free-living Dutch frail elderly (143 women

  14. Living Together: The Impact of the Intifada and the Peace Negotiations on Attitudes toward Coexistence of Arab and Jewish Pupils in Ethnically Segregated and Mixed Schools in Jaffa.

    Science.gov (United States)

    Zuzovsky, Ruth

    1997-01-01

    Changes in the willingness of Jews and Arabs to coexist were studied in 1989 with 217 12-year-olds and in 1994 with 194 in Jaffa (Israel), where both Jews and Arabs live. Separatist attitudes increased and faith in coexistence decreased, but mixed schools seemed to improve attitudes toward coexistence. (SLD)

  15. Use of radiography in public dental care for children and adolescents in northern Sweden

    DEFF Research Database (Denmark)

    Falk Kieri, Catarina; Twetman, Svante; Stecksén-Blicks, Christina

    2009-01-01

    -oral radiographs with a mean number of 19+/-4 exposures. There was a statistically significant difference (pgender-related differences were displayed. During preschool ages, bitewing radiographs were taken in less than 10......% of the children. Children treated at specialist clinics in orthodontics displayed higher number of radiographic examinations than non-referred children (pdetection were the most common radiographic examination. Fewer bitewing...

  16. Abstinence, Social Norms, and Drink Responsibly Messages: A Comparison Study

    Science.gov (United States)

    Glassman, Tavis J.; Kruger, Jessica Sloan; Deakins, Bethany A.; Paprzycki, Peter; Blavos, Alexis A.; Hutzelman, Erin N.; Diehr, Aaron

    2016-01-01

    Objective: The purpose of this study was to determine which type of prevention message (abstinence, social norms, or responsible drinking) was most effective at reducing alcohol consumption. Participants: The subjects from this study included 194 college students from a public university. Methods: Researchers employed a quasi-experimental design,…

  17. Long the fixation of physicists worldwide, a tiny particle is found

    CERN Multimedia

    2006-01-01

    "After decades of intensive effort by both experimental and theoretical physicists worldwide, a tiny particle with no charge, a very low mass and a lifetime much shorter than a nanosecond, dubbed the "axion", has now been detected by the University at Buffalo physicist who first suggested its existence in a little-read paper as early as 194." (2 pages)

  18. Disease: H00548 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available pers HH, Hamel BC X-linked mental retardation. Nat Rev Genet 6:46-57 (2005) PMID:8862875 Brunner HG MAOA deficiency and abnormal beha...viour: perspectives on an association. Ciba Found Symp 194:155-64; discussion 164-7 (1996) ...

  19. Multiplex polymerase chain reaction-based prognostic models in diffuse large B-cell lymphoma patients treated with R-CHOP

    DEFF Research Database (Denmark)

    Green, Tina M; Jensen, Andreas K; Holst, René;

    2016-01-01

    We present a multiplex analysis for genes known to have prognostic value in an attempt to design a clinically useful classification model in patients with diffuse large B-cell lymphoma (DLBCL). Real-time polymerase chain reaction was used to measure transcript levels of 28 relevant genes in 194 de...

  20. The origins of formal education in sub-Saharan Africa: was British rule more benign?

    NARCIS (Netherlands)

    Frankema, E.H.P.

    2012-01-01

    British colonial rule has often been praised for its comparatively benign features, such as its support of local educational development. This study argues that the impact of British educational policies and investments on the supply of schooling in British Africa should not be overstated. Until 194

  1. Structural Impediments to African Growth? New Evidence from British African Real Wages, 1880-1965

    NARCIS (Netherlands)

    Frankema, E.H.P.; Waijenburg, van M.

    2012-01-01

    British colonial rule has often been praised for its comparatively benign features, such as its support of local educational development. This study argues that the impact of British educational policies and investments on the supply of schooling in British Africa should not be overstated. Until 194

  2. 75 FR 8431 - Carbon Dioxide Fire Suppression Systems on Commercial Vessels

    Science.gov (United States)

    2010-02-24

    ... Homeland Security Coast Guard 46 Parts 25, 27, 28, et al. Carbon Dioxide Fire Suppression Systems on..., 182, 185, 189, 190, 193, 194, and 196 RIN 1625-AB44 Carbon Dioxide Fire Suppression Systems on... vessels. The amendments would clarify that approved alternatives to carbon dioxide systems may be used...

  3. 76 FR 10073 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2011-02-23

    .... \\3\\ See Securities Exchange Act Release No. 63609 (December 27, 2010), 76 FR 194 (``Notice''). \\4\\ In... exposure to a broad range of Asian government and corporate bonds through investment in both local currency... developing/emerging market economies in Asia, primarily China, Hong Kong, India, Indonesia, South...

  4. Self-Efficacy and Burnout in Professional School Counselors

    Science.gov (United States)

    Gunduz, Bulent

    2012-01-01

    This study investigated the relationships between burnout and self-efficacy among school counselors. Also, the level of their burnout and self-efficacy was examined in terms of the social support, task perception and the number of students. A sample of 194 school counselors filled out the Maslach Burnout Inventory, The School Counselors…

  5. Friends or lovers? Person- and variable-oriented perspectives on dyadic similarity in adolescent romantic relationships

    NARCIS (Netherlands)

    Seiffge-Krenke, I.; Burk, W.J.

    2013-01-01

    Variable- and person-oriented approaches were used to examine the affiliative and romantic experiences of adolescents in heterosexual romantic relationships and its associations with relationship conflict and jealousy on a sample of 194 romantic partner dyads. Variable-oriented findings indicated th

  6. Domain Modeling: NP_000881.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_000881.3 chr11 Crystal structure of a Kir3.1-prokaryotic Kir channel chimera p2qksb_ chr11/NP_000881.3.../NP_000881.3_apo_50-370.pdb blast 192Q,193P,194K,196R,210M,211R,212D,213E,228H,229I,23

  7. Domain Modeling: NP_001561.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001561.3 chr3 Structural Basis for the Interaction of TAK1 Kinase with its Activ...ating Protein TAB1 p2evaa_ chr3/NP_001561.3/NP_001561.3_holo_194-543.pdb psi-blast 216I,217S,218Q,219G,224V,

  8. Brief Report: Relationship between Non-Verbal IQ and Gender in Autism

    Science.gov (United States)

    Banach, Ryan; Thompson, Ann; Szatmari, Peter; Goldberg, Jeremy; Tuff, Lawrence; Zwaigenbaum, Lonnie; Mahoney, William

    2009-01-01

    It has been proposed that females at risk for autism are protected in some way, so that only those with the greatest genetic liability are affected. Consequently, affected male siblings of females with autism should be more impaired than affected male siblings of male probands. One hundred and ninety-four (194) families with a single child with…

  9. School Counselors' Systematic Perceptions of Change Agency through Primal Leadership and Empowerment: Critical Provisions towards K-12 Students' Achievement

    Science.gov (United States)

    Fay, Miriam Soler; Martin, Barbara Nell

    2005-01-01

    In this examination, 194 K-12 school counselors completed the Self-Perceptions of Effectiveness as Educational Change Agent (SPECA) survey. Analyses uncovered that Primal Leadership and personal power or empowerment both play a significant role in counselors' potential effectiveness to effect change regardless of gender or building level. Personal…

  10. The "Reading the Mind in the Voice" Test-Revised: A Study of Complex Emotion Recognition in Adults with and Without Autism Spectrum Conditions

    Science.gov (United States)

    Golan, Ofer; Baron-Cohen, Simon; Hill, Jacqueline J.; Rutherford, M. D.

    2007-01-01

    This study reports a revised version of the "Reading the Mind in the Voice" (RMV) task. The original task (Rutherford et al., (2002), "Journal of Autism and Developmental Disorders, 32," 189-194) suffered from ceiling effects and limited sensitivity. To improve that, the task was shortened and two more foils were added to each of the remaining…

  11. Mind and Body: Concepts of Human Cognition, Physiology and False Belief in Children with Autism or Typical Development

    Science.gov (United States)

    Peterson, Candida C.

    2005-01-01

    This study examined theory of mind (ToM) and concepts of human biology (eyes, heart, brain, lungs and mind) in a sample of 67 children, including 25 high functioning children with autism (age 6-13), plus age-matched and preschool comparison groups. Contrary to Baron-Cohen [1989, "Journal of Autism and Developmental Disorders," 19(4), 579-600],…

  12. 78 FR 38330 - Information Collection Being Reviewed by the Federal Communications Commission

    Science.gov (United States)

    2013-06-26

    ... Pornography and Marketing Act of 2003, CG Docket No. 04-53, FCC 04-194, published at 69 FR 55765, September 16... Federal Register on December 15, 2009 (74 FR 66356), which became effective on January 25, 2010. Privacy... Assault of Non-Solicited Pornography and Marketing Act of 2003, CG Docket No. 04-53. Form Number:...

  13. The use of lipids as phase change materials for thermal energy storage

    Science.gov (United States)

    Phase change materials (PCMs) are substances capable of absorbing and releasing large 2 amounts of thermal energy (heat or cold) as latent heat over constant temperature as they 3 undergo a change in state of matter (phase transition), commonly, between solid and 4 liquid phases. Since the late 194...

  14. The dark side of romantic relationships: Aggression in adolescent couples and links to attachment

    NARCIS (Netherlands)

    Seiffge-Krenke, I.; Burk, W.J.

    2015-01-01

    This study focuses on romantic relationships from the perspective of both partners. This dyadic approach was chosen to account for the fact that both partners may differently contribute to the escalation of aggression. In a sample of 194 romantic partner dyads, differences between female and male pa

  15. “Bad Romance”: Links between Psychological and Physical Aggression and Relationship Functioning in Adolescent Couples

    NARCIS (Netherlands)

    Seiffge-Krenke, I.; Burk, W.J.

    2015-01-01

    Assortative mating is an important issue in explaining antisocial, aggressive behavior. It is yet unclear, whether the similarity paradigm fully explains frequent displays of aggression in adolescents’ romantic relationships. In a sample of 194 romantic partner dyads, differences between female and

  16. From Caterpillar to Butterfly: A Window for Looking into Students' Ideas about Life Cycle and Life Forms of Insects

    Science.gov (United States)

    Cinici, Ayhan

    2013-01-01

    The purpose of this study was a qualitative analysis of high school students' ideas about life cycle and life forms of the butterfly. For this purpose, open-ended questions and drawing methods were applied to 194 high school students from the ninth to eleventh grades and 14 to 16 years of age in Erzurum, Turkey. Students' drawings were categorised…

  17. Früher Beginn: Aggression bei jugendlichen Paaren und ihr Bezug zu Partnerschaftsqualität und Bewältigung von Konflikten [Early start: Aggression in adolescent couples and its link to relationship quality and coping with conflicts

    NARCIS (Netherlands)

    Seiffge-Krenke, I.; Burk, W.J.

    2016-01-01

    Aggressive behavior in adult couples is a problem which must be taken seriously and is a frequent reason for psychotherapy and counseling. Less is known about an early start of aggression, e.g. in adolescent romantic relationships. In a sample of 194 romantic partner dyads (age 16-18 years) differen

  18. Biomedical applications of peptide nanostructures

    OpenAIRE

    Ekiz, Melis Şardan

    2016-01-01

    Cataloged from PDF version of thesis. Includes bibliographical references (leaves 171-194). Thesis (Ph. D.): Bilkent University, Materials Science and Nanotechnology Program, İhsan Doğramacı Bilkent University, 2016. by Melis Şardan Ekiz. Ph. D.

  19. Discovery of the Isotopes with 11 <= Z <= 19

    OpenAIRE

    Thoennessen, M

    2011-01-01

    A total of 194 isotopes with 11 $\\le$ Z $\\le$ 19 have been identified to date. The discovery of these isotopes which includes the observation of unbound nuclei, is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  20. Towards a Social Trust-aware Recommender for Teachers

    NARCIS (Netherlands)

    Fazeli, Soude; Drachsler, Hendrik; Brouns, Francis; Sloep, Peter

    2013-01-01

    Fazeli, S., Drachsler, H., Brouns, F., & Sloep, P. B. (2014). Towards a Social Trust-aware Recommender for Teachers. In N. Manouselis, H. Drachsler, K. Verbert & O. C. Santos (Eds.), Recommender Systems for Technology Enhanced Learning (pp. 177-194): Springer New York.

  1. Commentary on Carter, Stephenson and Strnadova's Reported Prevalence by Australian Special Educators of Evidence-Based Instructional Practices

    Science.gov (United States)

    Dempsey, Ian

    2011-01-01

    In Volume 35, Issue 1 of the "Australasian Journal of Special Education," Carter, Stephenson and Strnadova (2011) replicated a study by Burns and Ysseldyke (2009). In Carter et al.'s study, 194 Australian special educators were asked to rate the extent to which they used eight instructional practices. These practices were applied behaviour…

  2. Development of an Abbreviated Social Phobia and Anxiety Inventory (SPAI) Using Item Response Theory: The SPAI-23

    Science.gov (United States)

    Roberson-Nay, Roxann; Strong, David R.; Nay, William T.; Beidel, Deborah C.; Turner, Samuel M.

    2007-01-01

    An abbreviated version of the Social Phobia and Anxiety Inventory (SPAI) was developed using methods based in nonparametric item response theory. Participants included a nonclinical sample of 1,482 undergraduates (52% female, mean age = 19.4 years) as well as a clinical sample of 105 individuals (56% female, mean age = 36.4 years) diagnosed with…

  3. AcEST: DK956074 [AcEST

    Lifescience Database Archive (English)

    Full Text Available Oryzain alpha chain OS=Oryza sativa subsp. ... 139 8e-33 sp|Q94B08|GCP1_ARATH Germination... 183 DCDTSYNEGCNG 194 >sp|Q94B08|GCP1_ARATH Germination-specific cysteine protease 1 OS=Arabidopsis thaliana

  4. How Reading Strategy Use and Personality Types Are Related?

    Science.gov (United States)

    Safdarian, Zahra; Ghyasi, Majid; Farsani, Mohammad Amini

    2014-01-01

    This study sought to uncover the reading strategies utilized by Iranian undergraduate English Foreign Language (EFL) learners and their relationship with personality types. To this end, 194 university EFL learners were asked to fill out the Myers-Briggs Type Indicator (MBTI) to identify their personality types and answer a reading strategy…

  5. Androgyny, Masculinity, and Self-Esteem.

    Science.gov (United States)

    Lundy, Allan; Rosenberg, Judy A.

    1987-01-01

    Administered Coopersmith Self-Esteem Inventory and Bem Sex Role Inventory to 194 adults. Found androgyny scale emphasizing masculinity was most predictive of self-esteem, due to strong correlation found between masculinity and self-esteem. Found no effects due to femininity, interaction of femininity and masculinity, or sex. (Author/NB)

  6. Charismatic aspect of transformational leadership and its role in creating organizational culture / Gerda Mihhailova, Kulno Türk

    Index Scriptorium Estoniae

    Mihhailova, Gerda

    2006-01-01

    Ettevõtte kasvu- ja küpsusfaasis vajatakse autorite hinnangul enam nn. klassikalisi juhte, karismaatilised juhid sobivad pigem radikaalseid muutusi nõudvatesse situatsioonidesse, nagu näiteks ettevõtte rajamine või selle langusfaasist välja toomine. Skeemid. Tabel. Lisa lk. 194

  7. AcEST: BP916097 [AcEST

    Lifescience Database Archive (English)

    Full Text Available |PALY_AMAMU Phenylalanine ammonia-lyase OS=Amanita musc... 30 8.8 sp|Q32LL5|INT12_BOVIN Integrator complex s...----AYC 194 >sp|O93967|PALY_AMAMU Phenylalanine ammonia-lyase OS=Amanita muscaria

  8. EGF61A>G polymorphism as predictive marker of clinical outcome to first-line capecitabine and oxaliplatin in metastatic colorectal cancer

    DEFF Research Database (Denmark)

    Spindler, Karen-Lise Garm; Andersen, R F; Jensen, Lars Henrik;

    2010-01-01

    samples. Response was evaluated according to the RECIST. Survival analysis was described by the Kaplan-Meier method and log-rank testing. RESULTS: The overall response rate was 38% and the median overall survival 19.4 months. A favorable outcome was seen in patients with the EGF61A/G genotype compared...

  9. The quasi-continuum of gamma rays following the decay of superdeformed bands in the Hg region

    Energy Technology Data Exchange (ETDEWEB)

    Lauritsen, T.; Khoo, T.L.; Janssens, R.V.F. [Argonne National Lab., IL (United States)] [and others

    1996-12-31

    The quasi-continuum part of the spectrum associated with the decay-out of the yrast superdeformed band in {sup 194}Hg has been extracted. It has for the first time been possible to compare the spin and excitation energy determined from the analysis of the quasi-continuum {gamma} rays to the exact result obtained from the one-step linking transitions.

  10. Stereotype Threat and Gender Differences in Performance on a Novel Visuospatial Task

    Science.gov (United States)

    Campbell, Susan Miller; Collaer, Marcia L.

    2009-01-01

    Stereotype threat research has shown that being a member of a negatively stereotyped group may result in impaired performance on tests of skills thought to be relevant to the stereotype. This study investigated whether stereotype threat influences gender differences in performance on a novel test of visuospatial ability. Undergraduates (N = 194)…

  11. Population genetic structure in farm and feral American mink (Neovison vison) inferred from RAD sequencing-generated single nucleotide polymorphisms

    DEFF Research Database (Denmark)

    Thirstrup, Janne Pia; Ruiz-Gonzalez, Aritz; Pujolar, José Martin;

    2015-01-01

    Feral American mink populations (Neovison vison), derived from mink farms, are widespread in Europe. In this study we investigated genetic diversity and genetic differentiation between feral and farm mink using a panel of genetic markers (194 SNP) generated from RAD sequencing data. Sampling incl...

  12. Robust Eye and Pupil Detection Method for Gaze Tracking

    Directory of Open Access Journals (Sweden)

    Su Yeong Gwon

    2013-02-01

    The experimental results show that the proposed method can detect the center of the pupil at a speed of approximately 19.4 frames/s with an RMS error of approximately 5.75 pixels, which is superior to the performance of conventional detection methods.

  13. Aggregation studied by laser diffraction in relation to plowing and liming in the Cerrado region in Brazil

    NARCIS (Netherlands)

    Westerhof, R.; Buurman, P.; Griethuysen, van C.; Ayarza, M.; Vilela, L.; Zech, W.

    1999-01-01

    In the Cerrado savanna region in Brazil, the effects of different land use on axisol aggregation were studied using laser diffraction grain size analyses. The topsoil of plowed systems had significantly lower amount of macroaggregates (2000-194 μm) and a significantly higher amount of soil in the mi

  14. Use of the GMFCS in infants with CP : the need for reclassification at age 2 years or older

    NARCIS (Netherlands)

    Gorter, Jan Willem; Ketelaar, Marjolijn; Rosenbaum, Peter; Helders, Paul J. M.; Palisano, Robert

    2009-01-01

    The stability of the Gross Motor Function Classification System (GMFCS) over time is described in 77 infants (41 boys, 36 girls) with cerebral palsy (CP; mean age 19.4mo [SD 1.6 mo]; 27 unilateral spastic, 42 bilateral spastic, eight dyskinetic type) and in the same children at follow-up at age 2 to

  15. A Randomized Study of a Literacy-Integrated Science Intervention for Low-Socio-Economic Status Middle School Students: Findings from First-Year Implementation

    Science.gov (United States)

    Tong, Fuhui; Irby, Beverly J.; Lara-Alecio, Rafael; Guerrero, Cindy; Fan, Yinan; Huerta, Margarita

    2014-01-01

    This paper presents the findings from a randomized control trial study of reading/literacy-integrated science inquiry intervention after 1 year of implementation and the treatment effect on 5th-grade low-socio-economic African-American and Hispanic students' achievement in science and English reading. A total of 94 treatment students and 194

  16. Study of Locomotor Disability due to Various Types of Trauma

    Directory of Open Access Journals (Sweden)

    Sandip Rameshrao Dhole

    2015-09-01

    Conclusion: Trauma contributes not only to significant number of disabilities, but also to severity of disability. Road traffic accidents and railway accidents are major causes of traumatic locomotor disability and young persons are the usual victims of such disasters. [Natl J Med Res 2015; 5(3.000: 194-198

  17. Gclust Server: 194123 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 194123 Ctep_CT0791 Cluster Sequences - 145 hypothetical protein 1 1.00e-80 0.0 0.0 0.0 6.67 0.0 0.0 Show 194...123 Cluster ID 194123 Sequence ID Ctep_CT0791 Link to cluster sequences Cluster Seq

  18. Gclust Server: 194136 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 194136 Ctep_CT0811 Cluster Sequences - 145 hypothetical protein 1 1.00e-70 0.0 0.0 0.0 6.67 0.0 0.0 Show 194...136 Cluster ID 194136 Sequence ID Ctep_CT0811 Link to cluster sequences Cluster Seq

  19. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 7, Revision 4 (FGE.07Rev4): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5

    DEFF Research Database (Denmark)

    Larsen, John Christian; Nørby, Karin Kristiane; Beltoft, Vibe Meister;

    substances, the specifications for the materials of commerce have also been considered. For three substances [FL-no: 02.194, 02.211 and 02.255] the stereoisomeric compositions have not been given and for one substance [FL-no: 07.156] information on the composition of the stereoisomeric mixture is lacking....

  20. 78 FR 14421 - Proposed Collection; Comment Request for Regulation Project

    Science.gov (United States)

    2013-03-05

    ...(c)(2)(A)). Currently, the IRS is soliciting comments concerning Amortization of Reforestation... Reforestation Expenditures. OMB Number: 1545-0735. Regulation Project Number: TD 7927. Abstract: Internal Revenue Code section 194 allows taxpayers to elect to amortize certain reforestation expenditures over a...

  1. Parent Reports of Young Spanish-English Bilingual Children's Productive Vocabulary: A Development and Validation Study

    Science.gov (United States)

    Mancilla-Martinez, Jeannette; Gámez, Perla B.; Vagh, Shaher Banu; Lesaux, Nonie K.

    2016-01-01

    Purpose: This 2-phase study aims to extend research on parent report measures of children's productive vocabulary by investigating the development (n = 38) of the Spanish Vocabulary Extension and validity (n = 194) of the 100-item Spanish and English MacArthur-Bates Communicative Development Inventories Toddler Short Forms and Upward Extension…

  2. Polymorphisms of DNA repair genes XRCC1 and XRCC3, interaction with environmental exposure and risk of chronic gastritis and gastric cancer

    Institute of Scientific and Technical Information of China (English)

    Márcia Cristina Duarte; Jucimara Colombo; Andrea Regina Baptista Rossit; Alaor Caetano; Aldenis Albaneze Borim; Durval Wornrath; Ana Elizabete Silva

    2005-01-01

    AIM: To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population.METHODS: Genotyping by PCR-RFLP was carried out on 202 patients with chronic gastritis (CG) and 160 patients with gastric cancer (GC), matched to 202 (C1) and 150(C2) controls, respectively.RESULTS: No differences were observed among the studied grou ps with regard to the genotype distribution of XRCC1 codons 194 and 399 and of XRCC3 codon 241. However, the combined analyses of the three variant alleles (194Trp, 399Gln and 241Met) showed an increased risk for chronic gastritis when compared to the GC group. Moreover, an interaction between the polymorphic alleles and demographic and environmental factors was observed in the CG and GC groups. XRCC1 194Trp was associated with smoking in the CG group,while the variant alleles XRCC1 399Gln and XRCC3241Met were related with gender, smoking, drinking and H pylori infection in the CG and GC groups.CONCLUSION: Our results showed no evidence of a rela-tionship between the polymorphisms XRCC1Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk of chronic gastritis and gastric cancer in the Brazilian population, but the combined effect of these variants may interact to increase the risk for chronic gastritis,considered a premalignant lesion. Our data also indicate a gene-environment interaction in the susceptibility to chronic gastritis and gastric cancer.

  3. Construction and characterization of double mutants in nitrogenase of Klebsiella pneumoniae

    Institute of Scientific and Technical Information of China (English)

    ZHAO Dehua; LI Jilun

    2004-01-01

    Two mutants in nitrogenase of Klebsiella pneumoniae are constructed by site-directed mutagenesis and gene replacement procedure, which express the nitrogenases with Lysine and Glutamine substituting for α-Glutamine 190and α-Histidine 194 respectively (Kp-Q α190 K and Kp-H α194 Q). The above two substitutions are respectively introduced into a nifV mutant (expressing a citrate-containing nitrogenase) and sequentially two double mutants are obtained (Kp-Q α190 K-nifV- and Kp-H α194 Q-nifV-). All four mutants exhibit strict Nif- phenotype under the N2-fixation condition and fail to grow diazotrophically. Altered nitrogneases are effeetively depressed and the C2H2 reduction analysis shows that the double substitutions in Kp-Q α190K-nifV abolish cell C2H2 reduction activity, but Kp-H α194Q-nifV cells maintain a C2H2 reduction activity at 10% of that of wild type. Whole cell C2D2 reduction by all four mutants in comparison to the wild type and nifV mutant is also detected. The results show that only single α-Gln194 substitution does not perturb the stereospecificity of protonation of C2D2. These results indicate that the α- Glutamine 190 and its combination with homocitrate are essential to the catalytic activity of nitrogenase and it is proposed that α-Glutamine 190 and its combination with homocitrate are involved in the proton and/or electron transfer to FeMoco. The nitrogenases from these double mutants will be useful in further analysis of the entry of the proton and/or electron to FeMoco and the substrate binding sites.

  4. Immuno-vectorization of radioelements emitters of alpha particles: a new therapy in cancerology

    International Nuclear Information System (INIS)

    The radio-immunotherapy is an anti cancerous therapy which consists in vectorising with immuno-specific agents very radio toxic radioelements on tumors or in their environment to destroy them. The first part of this report presents the different characteristics of antibodies as well as their means of production under monoclonal shapes specifically steered against a tumoral antigen of interest. The second part of this report replaces the importance of the immunological vectors in the context of the nuclear medicine. It is notably described that the different methods which allow to radio-label the vector, as well as the different ways of optimization which were envisaged to improve the targeting of radioelements on a tumor. These different developments allow to define the potential place of the alpha radio-immunotherapy in treatments and so re-place the interest of the experimental part. If the radio-immunotherapy, using beta emitters isotopes as the 131iodine or the90yttrium, is today current in anti cancerous therapy, it finds limits because of the disintegration characteristics of the isotopes it uses. Indeed, compared with alpha particles, the beta particles deposit less energy by unit of length in the crossed material.The experimental part of this report aims at studying the feasibility of the coupling between an immunological vector and an alpha emitter isotope.The different tests led on the bismuth 213, the bismuth 212, the lead 212 and the astatine 211 demonstrated that the fixation of these radionuclides was possible. This research theme is strengthened by the construction in Nantes of a cyclotron with high energy ( A.R.R.O.N.A.X.) and the optimization of the obtained promising results should allow a therapeutic use in oncology of the alpha radio-immunotherapy. (N.C.)

  5. Immuno-vectorization of radioelements emitters of alpha particles: a new therapy in cancerology; Immunovectorisation de radioelements emetteurs de particules alpha: une nouvelle voie therapeutique en cancerologie

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, M

    2007-05-15

    The radio-immunotherapy is an anti cancerous therapy which consists in vectorising with immuno-specific agents very radio toxic radioelements on tumors or in their environment to destroy them. The first part of this report presents the different characteristics of antibodies as well as their means of production under monoclonal shapes specifically steered against a tumoral antigen of interest. The second part of this report replaces the importance of the immunological vectors in the context of the nuclear medicine. It is notably described that the different methods which allow to radio-label the vector, as well as the different ways of optimization which were envisaged to improve the targeting of radioelements on a tumor. These different developments allow to define the potential place of the alpha radio-immunotherapy in treatments and so re-place the interest of the experimental part. If the radio-immunotherapy, using beta emitters isotopes as the {sup 131}iodine or the{sup 90}yttrium, is today current in anti cancerous therapy, it finds limits because of the disintegration characteristics of the isotopes it uses. Indeed, compared with alpha particles, the beta particles deposit less energy by unit of length in the crossed material.The experimental part of this report aims at studying the feasibility of the coupling between an immunological vector and an alpha emitter isotope.The different tests led on the bismuth 213, the bismuth 212, the lead 212 and the astatine 211 demonstrated that the fixation of these radionuclides was possible. This research theme is strengthened by the construction in Nantes of a cyclotron with high energy ( A.R.R.O.N.A.X.) and the optimization of the obtained promising results should allow a therapeutic use in oncology of the alpha radio-immunotherapy. (N.C.)

  6. Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.

    Science.gov (United States)

    Sholukh, Anton M; Watkins, Jennifer D; Vyas, Hemant K; Gupta, Sandeep; Lakhashe, Samir K; Thorat, Swati; Zhou, Mingkui; Hemashettar, Girish; Bachler, Barbara C; Forthal, Donald N; Villinger, Francois; Sattentau, Quentin J; Weiss, Robin A; Agatic, Gloria; Corti, Davide; Lanzavecchia, Antonio; Heeney, Jonathan L; Ruprecht, Ruth M

    2015-04-21

    Although IgA is the most abundantly produced immunoglobulin in humans, its role in preventing HIV-1 acquisition, which occurs mostly via mucosal routes, remains unclear. In our passive mucosal immunizations of rhesus macaques (RMs), the anti-HIV-1 neutralizing monoclonal antibody (nmAb) HGN194, given either as dimeric IgA1 (dIgA1) or dIgA2 intrarectally (i.r.), protected 83% or 17% of the RMs against i.r. simian-human immunodeficiency virus (SHIV) challenge, respectively. Data from the RV144 trial implied that vaccine-induced plasma IgA counteracted the protective effector mechanisms of IgG1 with the same epitope specificity. We thus hypothesized that mucosal dIgA2 might diminish the protection provided by IgG1 mAbs targeting the same epitope. To test our hypothesis, we administered HGN194 IgG1 intravenously (i.v.) either alone or combined with i.r. HGN194 dIgA2. We enrolled SHIV-exposed, persistently aviremic RMs protected by previously administered nmAbs; RM anti-human IgG responses were undetectable. However, low-level SIV Gag-specific proliferative T-cell responses were found. These animals resemble HIV-exposed, uninfected humans, in which local and systemic cellular immune responses have been observed. HGN194 IgG1 and dIgA2 used alone and the combination of the two neutralized the challenge virus equally well in vitro. All RMs given only i.v. HGN194 IgG1 became infected. In contrast, all RMs given HGN194 IgG1+dIgA2 were completely protected against high-dose i.r. SHIV-1157ipEL-p challenge. These data imply that combining suboptimal defenses at the mucosal and systemic levels can completely prevent virus acquisition. Consequently, active vaccination should focus on defense-in-depth, a strategy that seeks to build up defensive fall-back positions well behind the fortified frontline.

  7. 溶剂法回收废旧聚酯纺织品技术%Recovery of waste polyester textiles via solvent method

    Institute of Scientific and Technical Information of China (English)

    石娜; 武志云; 汪少朋; 甘胜华

    2012-01-01

    Polyester (PET) and polyester/cotton fabrics were dissolved by dimethyl sulfoxide (DMSO) for recycled use. The results show that polyester fabric can be dissolved easily in DMSO for recovery, especially at 185 - 194 ℃ , faster dissolving is observed and dissolving can be completed within 12 minutes. Meanwhile, within certain length of time DMSO dissolves polyester but cotton fibers. Therefore, for separating and recovering, put polyester /cotton fabrics into the DMSO reagent, dissolve them at 185 - 194 ℃ for 60 minutes, then recover the cotton fibers by filtering and recover polyester from the solution at around 185 - 194 ℃. The recycled cotton fibers exhibit stable properties and find wide spectrum of applications. The intrinsic viscosity of regenerated PET increased with the increase of recovery percentage of DMSO.%利用二甲基亚砜(DMSO)溶解纯涤纶织物及涤/棉混纺织物,回收利用涤纶(PET)和棉纤维.结果表明,DMSO试剂可以回收纯涤纶织物,尤其当温度在185~194℃时DMSO与纯涤纶织物溶解反应相对较快,溶解时间为12 min.在一定反应时间内DMSO易溶解涤纶而不溶解棉纤维,可将其用于回收聚酯和棉纤维.涤/棉织物投入到温度为185~194℃的DMSO试剂中,溶解60 min,可将不溶于DMSO试剂的棉纤维在温度为185~194℃的条件下滤出并回收,同时从溶解液中回收聚酯.回收的棉纤维性能稳定,运用领域广泛.再生聚酯的特性黏度随DMSO试剂回收率的增加而增大.

  8. HIV DNA loads, plasma residual viraemia and risk of virological rebound in heavily treated, virologically suppressed HIV-infected patients.

    Science.gov (United States)

    Gianotti, N; Canducci, F; Galli, L; Cossarini, F; Salpietro, S; Poli, A; Nozza, S; Spagnuolo, V; Clementi, M; Sampaolo, M; Ceresola, E R; Racca, S; Lazzarin, A; Castagna, A

    2015-01-01

    In this single-centre, retrospective study, we analyzed data of 194 patients receiving antiretroviral therapy with <50 human immunodeficiency virus (HIV) RNA copies/mL in plasma and 318 HIV RNA/DNA paired samples. By kinetic polymerase chain reaction (kPCR) molecular system analysis, 104 (54%) subjects had undetectable HIV RNA and 90 (46%) had residual viraemia. Median (interquartile range) HIV DNA load was 780 (380-1930) copies/10(6) peripheral blood lymphocytes (PBL), and HIV DNA loads were independently associated with residual viraemia (p 0.002). Virological rebound occurred in 29/194 (15%) patients over a median (interquartile range) follow-up of 17.5 (13.5-31.5) months. Residual viraemia (p 0.002), but not HIV DNA load, was independently associated with virological rebound.

  9. Association study between XRCC1 gene polymorphisms and sporadic amyotrophic lateral sclerosis.

    Science.gov (United States)

    Coppedè, Fabio; Migheli, Francesca; Lo Gerfo, Annalisa; Fabbrizi, Maria Rita; Carlesi, Cecilia; Mancuso, Michelangelo; Corti, Stefania; Mezzina, Nicoletta; del Bo, Roberto; Comi, Giacomo P; Siciliano, Gabriele; Migliore, Lucia

    2010-01-01

    The aim of the present study was to investigate the possible contribution of three common functional polymorphisms in the DNA repair protein X-ray repair cross-complementing group 1 (XRCC1), namely Arg194Trp (rs1799782), Arg280His (rs25489) and Arg399Gln (rs25487), to sporadic amyotrophic lateral sclerosis (SALS). We genotyped 206 Italian SALS patients and 203 matched controls for XRCC1 Arg194Trp, Arg280His and Arg399Gln polymorphisms by means of PCR/RFLP technique, searching for association between any of the studied polymorphisms and disease risk, age and site of onset. We observed a statistically significant difference in XRCC1 Gln399 allele frequencies between SALS cases and controls (0.39/0.28; p=0.001). The present study suggests that the XRCC1 Arg399Gln polymorphism might contribute to SALS risk. PMID:19707910

  10. Analytical validation of the Roche 25-OH Vitamin D Total assay

    DEFF Research Database (Denmark)

    Knudsen, Cindy Soendersoe; Nexo, Ebba; Højskov, Carsten Schriver;

    2012-01-01

    evaluated the 25-OH Vitamin D Total assay in comparison to our in-house liquid chromatography tandem mass spectrometry (LC-MS/MS) method [194 patient samples without 25-hydroxy vitamin D2 (25OHD2) and 23 patient samples containing 25OHD2]. Results: At concentrations of 34 and 56 nmol/L within-run CVs were 4.......8% and 1.9% and total CVs were 8.3% and 6.1%. We verified that the limit of quantification was 22.5 nmol/L, as stated by the manufacturer. No significant difference was observed between serum and plasma samples (Li-heparin). Comparison with LC-MS/MS using 194 samples containing 25OHD3 only (no 25OHD2...

  11. Interdisciplinary approach to clinical placements within Charles Sturt University School of Nursing Midwifery and Indigenous Health. A Practice Report

    Directory of Open Access Journals (Sweden)

    Jessica Maree Biles

    2015-03-01

    Full Text Available The clinical placement environment can be challenging for many students, and for students enrolled in the School of Nursing, Midwifery and Indigenous Health (SNMIH subject NRS194, Indigenous Cultures, Health and Nursing, being placed in an Aboriginal facility can be daunting and increase anxiety within a cohort.  A pilot project within the SNMIH for NRS194 sought to engage the local Aboriginal Health Service through Aboriginal staff and utilising the skills, knowledge and expertise of the Aboriginal Health workers as a conduit to the community.  The cross cultural engagement within the SNMIH and the community has meant the cohorts of discipline-specific programs are being exposed to a breadth and depth of diversity within the Australian Health context, with a specific focus on Aboriginal and Torres Strait Islander peoples and their communities.  This Practice Report discusses the core elements of this first year placement initiative and the outcomes from the academic lens.

  12. Proposed standard-weight (Ws) equation and length-categorization standards for brown trout (Salmo trutta) in lentic habitats

    Science.gov (United States)

    Hyatt, M.W.; Hubert, W.A.

    2001-01-01

    We developed a standard-weight (Ws) equation for brown trout (Salmo trutta) in lentic habitats by applying the regression-line-percentile technique to samples from 49 populations in North America. The proposed Ws equation is log10 Ws = -5.422 + 3.194 log10 TL, when Ws is in grams and TL is total length in millimeters. The English-unit equivalent is log10 Ws = -3.592 + 3.194 log10 TL, when Ws is in pounds and TL is total length in inches. The equation is applicable for fish of 140-750 mm TL. Proposed length-category standards to evaluate fish within populations are: stock, 200 mm (8 in); quality, 300 mm (12 in); preferred, 400 mm (16 in); memorable, 500 mm (20 in); and trophy, 600 mm (24 in).

  13. Sporopollen and algae research of core B106 in the northern South China Sea and its paleoenvironmental evolution

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Based on the high-resolution sporopollen and algae research of the sediments from core B106 in the northem South China Sea,three sporopollen assemblage zones have been distinguished in ascending order:Zone 1 (294-194 cm):pinus-Quercus (evergreen)-Gramineae-Polypodia-ceae- Pterdium-Dicranopteris.Zone 2 (194-94 cm):Pinus-Quercus (evergreen)-Polypodiaceae-Pteridium- Dicranopteris.Zone 3 (94-4 cm):Pinus-Polypodiaceae-Pteridium-Quercus(evergreen)-Dicranopteris.The three sporopollen zones correspond to three stages of vegetation,climate and paleoenvironment evolution of the northern part of the South China Sea since 11 000 years ago.Combined with AMS 14C dating,the sporopollen and algae data can be a scientific basis for stratigraphic division and reconstruction of paleoclimate and paleoenvironment in the South China Sea.

  14. Composition Analysis of Rose Oil Extracted by Molecular Distillation%用分子蒸馏技术提取的玫瑰精油的成分分析

    Institute of Scientific and Technical Information of China (English)

    张静菊; 郭永来; 李凤英; 李洪英

    2011-01-01

    Through GC-MS analytical method, the compositions of the rose oil extracted by molecular distillation are analyzed, and 78 kinds of chemical compounds have been identified. There are 20 kinds of compound with content more than 1 % , including 22. 606% phenethyl alcohol, 12.015% citronellol, 6.772% geraniol, 6.194% eugenol, and 2.329% neroli alcohol.%采用GC-MS分析方法,对分子蒸馏法提取的玫瑰精油成分进行分析,共鉴定出78种化学成分,含量大于1%的成分20种,其中苯乙醇22.606%、香茅醇12.015%、香叶醇6.772%、丁子香酚6.194%、橙花醇2.329%.

  15. 磷含量对Cu-Fe-P合金组织与性能的影响%Effect of P content on microstructure and property of Cu-Fe-P alloys

    Institute of Scientific and Technical Information of China (English)

    董琦祎; 汪明朴; 贾延琳; 陈畅; 夏承东

    2013-01-01

    Microstructure of cold roiled and aged Cu-2.3Fe-0.6P-0.2Zn alloy were observed by OM and SEM,and compared with that of Cu-2.3Fe-0.05P-0.2Zn(C194) alloy.The hardness and relative electrical conductivity of the alloys were measured.The results show that Fe2P phase is the main form of P in the as-cast alloy,a part of Fe2P is solid-solutioned in matrix,and the rest up to 10μm are dispersed in the alloy,which can not be eliminated by subsequent heat treatment.The performance of rolled Cu-2.3Fe-0.6P-0.2Zn alloy is better than the C194 alloy,but its conductivity improvement rate is slower than C194 alloy during aging,due to the low concentration of solute atoms and low driving force of precipitation.The micron Fe2P particles will stimulate recrystallization,and worsen the heat resistance of Cu-2.3Fe-0.6P-0.2Zn alloy.Consequently,the P content of C194 alloy should be controlled.%通过显微硬度及相对电导率测试、光学显微镜和扫描电镜观察,研究了Cu-2.3Fe-0.05P-0.2Zn (C194)合金与Cu-2.3Fe-0.6P-0.2Zn合金冷轧态与时效态的组织与性能.结果表明:添加0.6%P元素,铜合金内部形成大量Fe2P相,一部分固溶到基体,一部分以颗粒形式弥散存在于合金内,尺寸可达10μm,后续热处理难以消除;Cu-2.3 Fe-0.6P-0.2Zn合金的初始加工态性能优于C194合金,但基体中Fe溶质原子的浓度低,电导率上升速率变低;微米级Fe2P颗粒会激发再结晶,再结晶软化作用使得Cu-2.3Fe-0.6P-0.2Zn合金耐热性能低于C194合金.对于C194合金,P不宜过量.

  16. New information on the occurrence of the O(6) symmetry in nuclei

    International Nuclear Information System (INIS)

    New γγ-coincidence relations and E2 decay transition rates in the isotopes 194,196Pt have been deduced from γ-ray spectroscopy experiments using the Gammasphere spectrometer in projectile-Coulomb excitation reactions of beams of 194,196Pt ions provided by the ATLAS accelerator facility. The results give access to observables that are crucial for a classification of excited quadrupole-collective states in terms of quantum numbers associated with the analytically solvable O(6) dynamical symmetry of the interacting boson model. The data on 196Pt corroborate the qualitative pattern of excitation energies and E2 transition rates expected from the O(6) solution but the excitation energies significantly deviate from it on a quantitative level

  17. Fast-Neutron Activation of Long-Lived Nuclides in Natural Pb

    CERN Document Server

    Guiseppe, V E; Fields, N E; Hixon, D

    2012-01-01

    We measured the production of the long-lived nuclides Bi-207, Pb-202, and Hg-194 in a sample of natural Pb due to high-energy neutron interactions using a neutron beam at the Los Alamos Neutron Science Center. The activated sample was counted by a HPGe detector to measure the amount of radioactive nuclides present. These nuclides are critical in understanding potential backgrounds in low background experiments utilizing large amounts of Pb shielding due to cosmogenic neutron interactions in the Pb while residing on the Earth's surface. By scaling the LANSCE neutron flux to a cosmic neutron flux, we measure the sea level cosmic ray production rates of 8.0 +/- 1.3 atoms/kg/day of Hg-194, 120 +/- 25 atoms/kg/day Pb-202, and 0.17 +/- 0.04 atoms/kg/day Bi-207.

  18. 光强对杂交泡桐光合生理和荧光特性的影响%Effects of light intensity on photosynthetic physiology and chlorophyll fluorescence characteristics of hybrid Paulownia

    Institute of Scientific and Technical Information of China (English)

    王楠; 李芳东; 叶金山

    2015-01-01

    以杂交泡桐毛白33(即TF33)及其回交一代(BC1(194)和BC1(192))为材料,通过人工模拟旷地、林窗和林下3种光环境(分别为全光照L0、50%全光照L1、25%全光照L2),比较了不同光强下泡桐回交一代及其亲本TF33叶片的光合能力和叶绿素荧光特性的差异.结果显示:(1)遮荫后杂交泡桐净光合速率(Pn)日变化曲线由"双峰"型变为"单峰"型,日平均Pn随遮荫程度增加显著降低(P<0.05).L0条件下,BC1(194)和BC1(192)的日平均Pn未表现出杂种优势;L1条件下,BC1(192)和BC1(194)的日平均Pn杂种优势率(RH)分别为2.23%和3.67%;L2条件下,BC1(192)的日平均Pn高于TF33,但差异不显著,BC1(1舛)则表现为杂种劣势.(2)L0条件下,TF33的最大净光合速率(Pmax)和光饱和点(LSP)最大,光补偿点(LCP)和暗呼吸速率(Rd)最小;L1条件下,BC1(192)的Pmax、LSP和AQY最大,LCP和Rd最小;L2条件下,虽然BC1(194)和BC1(192)的Pmax低于TF33,但其LCP和Rd值也低于TF33.(3)L0条件下,TF33、BC1(194)和BC1(192)各荧光参数差异不显著;L1条件下,3个无性系的qP和qN差异显著,BC1(192)的热耗散最弱,光合能力最强;L2条件下,BC1(192)和TF33的qP差异不显著,BC1(194)与TF33差异显著,BC1(192)的Fv/Fm、F0和ETR与TF33、BC 1(194)差异显著(P<0.05).结果表明,TF33、BC1(1舛)和BC1(192)虽均对弱光有一定的调节适应机制,但在全光照下生长最为适宜,遮荫使植株的光合能力显著降低,光照不足成为其生长的决定性限制因子.在低光照(L1)条件下,BC1(194)和BC1(192)较其亲本TF33有光合优势.

  19. Transformation, evaluation of GTGene and multivariate genetic analysis for morpho-physiological and yield attributing traits in Zea mays

    Directory of Open Access Journals (Sweden)

    Aaliya Khadija

    2016-01-01

    Full Text Available Maize is the 3rd major crop grown all over the world that fulfills the needs of millions of people. Various biotic and abiotic factors caused reduction in grain yield of maize, among them weeds show most adverse effects. Objective of this study was to develop glyphosate resistance maize for developing maize hybrids and synthetic varieties with high grain and fodder yield potential. Glyphosate is a broad spectrum herbicide and resistance of crop against the herbicide, allows post emergence application, which otherwise is impossible. Higher GTG crude protein (479.94μg/g was recorded for CIL 194-975 plant. The plant CIL 194-1786 showed higher expression level of GTG protein, indicated that transformation efficiency was better for line CIL-194 than CIL-123. GTGene stably integrated to the genome of the maize lines CIL-194 and CIL-123, these transformed lines showed more ability to cope with herbicides as compared with non-transformed lines in greenhouse and field trials. The transgenic lines were sown in field and data was recorded for various morpho-physiological, grain, fodder yield and quality traits. Data was statistically analyzed to check significance of results at <0.05% probability level. It was concluded from heritability, genetic advance, stepwise multiple linear regression, principle component and factor analysis that the selection on the basis of grain yield, green fodder yield, stem diameter, cob weight, stomata conductance, chlorophyll contents, photosynthetic rate, cob length, grain protein, grain oil, embryo percentage and grain starch may be fruitful keeping in view as the major contributing traits to improve crop yield and production. It was suggested that the transgenic lines for glyphosate resistance may be used to develop transgenic hybrids and synthetic varieties with higher grain yield with high quality.

  20. Kidney stones and kidney function loss: a cohort study

    OpenAIRE

    Alexander, R Todd; Hemmelgarn, Brenda R; Wiebe, Natasha; Bello, Aminu; Morgan, Catherine; Samuel, Susan; Klarenbach, Scott W; Curhan, Gary C.; Tonelli, Marcello

    2012-01-01

    Objective To investigate whether the presence of kidney stones increase the risk of end stage renal disease (ESRD) or other adverse renal outcomes. Design A registry cohort study using validated algorithms based on claims and facility utilisation data. Median follow-up of 11 years. Setting Alberta, Canada, between 1997 and 2009. Participants 3 089 194 adult patients without ESRD at baseline or a history of pyelonephritis. Of these, 1 954 836 had outpatient serum creatinine measurements and we...

  1. The predictive value of ERG protein expression for development of castration-resistant prostate cancer in hormone-naïve advanced prostate cancer treated with primary androgen deprivation therapy

    DEFF Research Database (Denmark)

    Berg, Kasper Drimer; Røder, Martin A; Thomsen, Frederik B;

    2015-01-01

    BACKGROUND: Biomarkers predicting response to primary androgen deprivation therapy (ADT) and risk of castration-resistant prostate cancer (CRPC) is lacking. We aimed to analyse the predictive value of ERG expression for development of CRPC. METHODS: In total, 194 patients with advanced and...... in secondary endpoints were observed. CONCLUSIONS: ERG expression was not associated with risk of CRPC suggesting that ERG is not a candidate biomarker for predicting response to primary ADT in patients diagnosed with advanced and/or metastatic PCa....

  2. Study on the Wild Edible Raspberry Plant Resources and the Utilization in the Eastern Region of Guangdong Province%粤东地区野生可食悬钩子植物资源及利用研究

    Institute of Scientific and Technical Information of China (English)

    张福平

    2003-01-01

    @@ 悬钩子(Rubus L.)属于蔷薇科Rosaceae悬钩子属植物,在全世界有广泛分布,我国已报道的有194种,其中特有种138种,分布遍及全国各地,分布最为广泛的省(区)有云南、四川、贵州、广西、广东和福建等.

  3. Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies

    DEFF Research Database (Denmark)

    Mitchell, A. J.; Chan, M.; Bhatti, H.;

    2011-01-01

    settings. Prevalence of depression by DSM or ICD criteria was 16.3% (13.4-19.5); for DSM-defined major depression it was 14.9% (12.2-17.7) and for DSM-defined minor depression 19.2% (9-1-31.9). Prevalence of adjustment disorder was 19.4% (14.5-24.8), anxiety 10.3% (5.1-17.0), and dysthymia 2-7% (1...

  4. Oral Health-Related Quality of Life in institutionalized elderly in Barcelona (Spain)

    OpenAIRE

    Cornejo, Marco; Pérez de, Gloria; Lima, Kenio-Costa de; Casals Peidró, Elías; Borrell, Carme

    2013-01-01

    Objective: The objective of this study is to describe the oral health status and the factors associated with oral health-related quality of life (OHRQoL) in people aged 65 and older institutionalized in Barcelona in 2009. Study Design: Cross sectional study in 194 elderly. The dependent variable was poor OHRQoL, according to the Geriatric Oral Health Assessment Index (GOHAI). The independent variables were socio-demographic data, last dental visit, subjective and objective oral health status....

  5. Bank level stability factors and consumer confidence – a comparative study of Islamic and conventional banks’ product mix

    OpenAIRE

    Hussein, Kassim

    2010-01-01

    This study examines the behaviour of key bank level stability factors of liquidity, capital, risk-taking and consumer confidence in Islamic and conventional banks which operate in the same market. Using fixed effect sample of 194 banks of Gulf Cooperating Countries between 2000 and 2007, we found that liquidity is not determined by bank’s product mix but rather attributed to systematic factors. However, non performing assets (representing loans to sub prime borrowers) have positive and signif...

  6. Taxonomic Structure and Stability of the Bacterial Community in Belgian Sourdough Ecosystems as Assessed by Culture and Population Fingerprinting▿ †

    OpenAIRE

    Scheirlinck, Ilse; Van der Meulen, Roel; Van Schoor, Ann; Vancanneyt, Marc; De Vuyst, Luc; Vandamme, Peter; Huys, Geert

    2008-01-01

    A total of 39 traditional sourdoughs were sampled at 11 bakeries located throughout Belgium which were visited twice with a 1-year interval. The taxonomic structure and stability of the bacterial communities occurring in these traditional sourdoughs were assessed using both culture-dependent and culture-independent methods. A total of 1,194 potential lactic acid bacterium (LAB) isolates were tentatively grouped and identified by repetitive element sequence-based PCR, followed by sequence-base...

  7. Extraintestinal salmonellosis.

    OpenAIRE

    Wilkins, E G; Roberts, C

    1988-01-01

    Between 1969 and 1984, 6564 non-typhoid salmonella strains were isolated at the Liverpool Public Health Laboratory of which 194 (3.0%) were from extraintestinal sites. Blood (34%) and urine (32%) isolates accounted for two-thirds of these, with the remainder being recovered from pus and inflammatory tissue (23%), bone (5%), cerebrospinal fluid (5%) and sputum (3%). Certain serotypes tended to cause more invasive disease than others, i.e. Salmonella choleraesuis, S. dublin, S. london, S. virch...

  8. Effect of feed supplement on Milk Production, Fat % Total Serum Protein and Minerals in Lactating Buffalo

    OpenAIRE

    Verma, R. K.; Praveen Kumar; A. Adil and G.K. Arya

    2009-01-01

    A study was carried out to see the effect of feed supplement “Khurak” on milk yielding buffalo. The buffaloes were divided in two group. One group was offered “Khurak” as feed supplement for 7 days. Significant increase was observed in milk production, Total serum protein and calcium in khurak supplemented group (Treatment group). [Vet. World 2009; 2(5.000): 193-194

  9. An Evaluation of a Teat Dip with Dodecyl Benzene Sulfonic Acid in Preventing Bovine Mammary Gland Infection from Experimental Exposure to Streptococcus agalactiae and Staphylococcus aureus

    OpenAIRE

    Barnum, D A; Johnson, R. E.; Brooks, B W

    1982-01-01

    The effectiveness of a teat dip with dodecyl benzene sulfonic acid (1.94%) for the prevention of intramammary infections was determined in cows experimentally challenged with Streptococcus agalactiae and Staphylococcus aureus. The infection rates with Streptococcus agalactiae and Staphylococcus aureus were 62.5% and 75% in undipped quarters, 12.5% and 21.5% in dipped quarters with a reduction rate of 80% and 71% respectively. The significance of some findings in relation to mastitis control a...

  10. Emotion Regulation and Impulsivity in Young Adults

    OpenAIRE

    Schreiber, Liana R.N.; Grant, Jon E.; Odlaug, Brian L.

    2012-01-01

    Past research has linked both emotion regulation and impulsivity with the development and maintenance of addictions. However, no research has investigated the relationship between emotion regulation and impulsivity within young adults. In the present study, we analyzed 194 young adults (27.8% female; 21.3 ± 3.32 years old; 91.8% single; 85.1% Caucasian), grouping them as low, average, or high emotionally dysregulated, and compared self-reported impulsivity, impulsive behavio...

  11. A preliminary neutron diffraction analysis of Achromobacter protease I

    Science.gov (United States)

    Ohnishi, Yuki; Masaki, Takeharu; Yamada, Taro; Kurihara, Kazuo; Tanaka, Ichiro; Niimura, Nobuo

    2010-11-01

    Achromobacter protease I (API, E.C. 3.4.21.50) is one of the serine proteases produced by Achromobacter lyticus M497-1. API is distinct from the other tripsin type protease in its lysine specificity. The neutron structure analysis of catalytic triad with Trp169 and His210 was presented. His57 was double protonated and formed hydrogen bonds to Ser194Oγ and Asp113Oδ1, Oδ2.

  12. Frequencies of fetal chromosomal abnormalities at prenatal diagnosis: 10 years experiences in a single institution.

    OpenAIRE

    Park, S. Y.; J.W. Kim; Y.M. Kim; Kim, J.M.; Lee, M. H.; Lee, B. Y.; Han, J. Y.; Kim, M. Y.; Yang, J. H.; Ryu, H. M.

    2001-01-01

    We present frequencies of fetal chromosomal abnormalities in 4,907 prenatal cytogenetic examinations at Samsung Cheil Hospital from 1988 to 1997 for 10 yr duration. Prenatal karyotypes were undertaken in 3,913 amniotic fluid samples, 800 chorionic villi samples, and 194 percutaneous umbilical blood samples. The frequency of fetal abnormal karyotypes was 3.1% (150 cases). Numerical chromosome abnormalities were 87 cases (1.8%) and structural aberrations of chromosomes were 63 cases (1.3%). In ...

  13. Gclust Server: 157090 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available tive protein of unknown function, identified based on comparisons of the genome sequences of six Saccharomyc...157090 SCE_YGL194C-A Cluster Sequences - 80 Putative protein of unknown function, identified based on compar...isons of the genome sequences of six Saccharomyces species 1 1.00e-40 0.0 0.0 0.0 0

  14. Distribution of PSF of Near Earth Object Survey Telescope%近地天体望远镜的PSF分布研究

    Institute of Scientific and Technical Information of China (English)

    李彬; 赵海斌

    2012-01-01

    The field of view of CCD in NEOST (Near Earth Object Survey Telescope) is 1.94° × 1.94°. As a wide-field telescope, the focusing according to single stars leads to uneven distribution of PSF (Point Spread Function) due to the field curvature. The contour map of PSF's FWHM (Full Width at Half Maximum) indicates the features of the distribution of PSF. The focal surface is yielded by fitting the relation between defocus and PSF's FWHM. It is confirmed that the focal surface reshaped by the field lens is not fiat but convex, and the distance from the peak to the valley is about (85±5) μm. The center of the distribution of PSF deviates from the CCD center. This phenomenon is considered to be caused by the inclination of CCD. The method of getting the best-focus can be found by using the histogram of PSF's FWHM.%盱眙近地天体望远镜CCD视场为1.94°×1.94°,作为大视场望远镜由于存在场曲现象,因此根据单颗星像调焦会导致PSF (Point Spread Function)分布不均匀.研究所拍摄图像的PSF分布特征,并通过拟合半高全宽和离焦量的函数关系模拟出弯曲焦面,从而确定出最佳成像平面.制定出根据PSF的半高全宽直方图来判断最佳成像平面的调焦方法.

  15. AcEST: DK953647 [AcEST

    Lifescience Database Archive (English)

    Full Text Available icted protein OS=Physcomitrella paten... 353 4e-96 tr|A9QVH4|A9QVH4_9CONI Alpha tubulin OS=Picea wilsonii GN...STHSL 594 VVEPYNSVLSTHSL Sbjct: 181 VVEPYNSVLSTHSL 194 >tr|A9QVH4|A9QVH4_9CONI Alpha tubulin OS=Picea wils...onii GN=TUA1 PE=2 SV=1 Length = 451 Score = 353 bits (906), Expect = 4e-96 Identiti

  16. BY PRODUCT TERNAK. Teknologi dan Aplikasinya

    OpenAIRE

    Said, Muhammad Irfan

    2014-01-01

    DAFTAR PUSTAKA Adventini, N., Muhayatun, D. D. Lestiani dan W.Y.N. Syahfitri. 2012. Analisis Mikronutrien dalam Daging, Limpa, dan Hati Sapi. Jurnal Medika. 38 (8), 580???586. Angelidaki, I., and B. K. Ahring. 2000. Methods for increasing the biogas potential from the recalcitrant organic matter contained in manure. Water Science Technology. 41 (3), 189-194. Anonim. 1974. Gelita-Instant-Gelatins Type 800 A Type 800 B. Gelatine-Information-Service. Deutsche Gelatine-Febrike...

  17. Naturtyper og arter omfattet af EF-Habitatdirektivet

    DEFF Research Database (Denmark)

    Pihl, S.; Søgaard, B.; Ejrnæs, R.;

    Baggrund og formål I henhold til Habitatdirektivet (Det Europæiske Råd: Rådets direktiv 92/43/EØF af 21. maj 1992 om bevaring af naturtyper samt vilde dyr og planter) har Danmark udpeget i alt 194 habitatområder, der skal indgå i et europæisk netværk af særlige bevaringsområder, Natura 2000. Udpe...

  18. Intraoperative intravitreal triamcinolone decreases macular edema after vitrectomy with phacoemulsification

    OpenAIRE

    Murray, Timothy

    2012-01-01

    D Wilkin Parke III, Robert A Sisk, Timothy G MurrayDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USABackground: The purpose of this study was to evaluate the incidence and amount of macular edema by optical coherence tomography (OCT) after combined small gauge sutureless vitrectomy with phacoemulsification and intravitreal triamcinolone.Methods: This retrospective case series included 194 consecutive eyes undergoing noneme...

  19. Thoughts on Structure Adjustment of China's Refining Industry and Recommendations on Improving Economy of Scale

    Institute of Scientific and Technical Information of China (English)

    Cao Xianghong

    2002-01-01

    @@By the end of 1998 China boasted 220 refineries with a totalcrude processing capacity of 262 Mt/a. The average refinerysize at that time was 1.194 Mt/a. Refineries with processingcapacity exceeding 5.0 Mt/a accounted for only 21.26%,while the capacity of single refining units were also smallthat could not conform with the economy of scale. China'srefining industry is faced with a tough task of structureadjustment.   

  20. Thoughts on Structure Adjustment of China's Refining Industry and Recommendations on Improving Economy of Scale

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    @@ By the end of 1998 China boasted 220 refineries with a totalcrude processing capacity of 262 Mt/a. The average refinerysize at that time was 1.194 Mt/a. Refineries with processingcapacity exceeding 5.0 Mt/a accounted for only 21.26%,while the capacity of single refining units were also smallthat could not conform with the economy of scale. China'srefining industry is faced with a tough task of structureadjustment.

  1. 77 FR 2119 - WTO Dispute Settlement Proceeding Regarding China-Anti-Dumping and Countervailing Duty Measures...

    Science.gov (United States)

    2012-01-13

    ... From the Federal Register Online via the Government Publishing Office OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE WTO Dispute Settlement Proceeding Regarding China--Anti-Dumping and Countervailing... Anti-dumping Agreement; Articles 10, 12.3, 12.4.1, 12.7, 12.8, 15.1, 15.2, 15.4, 15.5, 16.1, 19.4,...

  2. GOVERNING OF LABOR SUPPLY IN BULGARIAN FARMS

    OpenAIRE

    Hrabrin Bachev

    2005-01-01

    This is the second paper from a series of articles on governing of different types of transactions in Bulgarian farming applying the framework of New Institutional and Transaction Cost Economics. It is based on a large scale microeconomic data from 194 typical commercial farms of different sizes and types from all regions of the country. This study concentrates on factors and modes for organization of labor supply in Bulgarian farms. Structure of kind of labor (permanent, seasonal, irregular,...

  3. The multiverse and the origin of our universe

    OpenAIRE

    Gehrels, Tom

    2007-01-01

    The multiverse is a hierarchy in the number of universes, increasing stepwise towards infinity. It is an evolutionary system, in which universes survive only near critical mass. That mass is actually a factor of 1.94 less than the critical mass, and this is found to be consistent with the baryon density inferred from nucleosynthesis in our universe; it is also precisely verified as a cosmological effect. That factor seems to have originated in the multiverse for causing intersecting expansion...

  4. Ambiente e paesaggio. Idee per i corsi di geografia e discipline ambientali

    OpenAIRE

    F.Canigiani

    2007-01-01

    Il volume Ambiente e paesaggio. Idee per i corsi di geografia e discipline ambientali (pagine 194) conduce il lettore attraverso quattro itinerari. Nel primo capitolo si vuole offrire una guida essenziale per orientarsi, sia nel campo della ricerca, sia a livello didattico, tra le complesse tematiche che ruotano intorno al concetto di ambiente, nel tentativo di puntualizzarne i contenuti e le diverse visuali. Il secondo capitolo ripercorre la storia delle idee ecologiche e lo sviluppo della c...

  5. PARENT'S AND FRIEND’S AS FACTORS OF CHILD’S BEHAVIOR AT SCHOOL: A COMPARISON OF MULTIPLE CORRELATIONS

    OpenAIRE

    Orhideja Shurbanovska

    2013-01-01

    Why are some children lonely, aggressive or they behaving prosocially at school? This study tends to answer the research question: how are family and peer relations associated with the social behavior of the pupils in mid childhood and early adolescence (3rd grade and 7th grade pupils), respectively. The hypotheses refer to the differences in the connections of the family and peer relations with the student’s social behavior at school. The data gathered from 194 examinees were elaborated in t...

  6. Role of human papillomavirus in determining the HLA associated risk of cervical carcinogenesis.

    OpenAIRE

    Mehal, W Z; Lo, Y M; Herrington, C. S.; Evans, M. F.; Papadopoulos, M.C.; Odunis, K; Ganesan, T. S.; McGee, J O; Bell, J. I.; Fleming, K A

    1994-01-01

    AIMS--To investigate the role of human papillomavirus (HPV) in the association between HLA DQw3 and squamous cell cancer of the cervix (SCCC). METHODS--Tissue from 194 cervical samples, ranging from normal, through cervical intraepithelial neoplasia, to SCCC, were typed for HPV by amplification of the L1 gene using degenerate consensus primers, followed by oligonucleotide probing. HLA DQw3 typing was undertaken in the same samples using a new PCR amplification system using primers common to a...

  7. Whole-Genome Transcription Profiling Reveals Genes Up-Regulated by Growth on Fucose in the Human Gut Bacterium “Roseburia inulinivorans”†

    OpenAIRE

    Karen P Scott; Martin, Jennifer C.; Campbell, Gillian; Mayer, Claus-Dieter; Flint, Harry J

    2006-01-01

    “Roseburia inulinivorans” is an anaerobic polysaccharide-utilizing firmicute bacterium from the human colon that was identified as a producer of butyric acid during growth on glucose, starch, or inulin. R. inulinivorans A2-194 is also able to grow on the host-derived sugar fucose, following a lag period, producing propionate and propanol as additional fermentation products. A shotgun genomic microarray was constructed and used to investigate the switch in gene expression that is involved in c...

  8. Data to the bryoflora of Mount Kenya, Kenya

    OpenAIRE

    Chuah-Petiot, Min S.

    1995-01-01

    194 species of bryophytes, belonging to 61 families are reported from Mount Kenya, of which 38 species are new for Mount Kenya and 30 records are new for the whole country, marked by * and ** respectively. The montane forests between 1600 and 3300m. asl., contain the greatest diversity of life forms and species. This is due to the abundant rainfall providing adequate humidity at relatively low temperature and altitude, coupled with frequent cloud cover. All vegetation belts above the montane ...

  9. Effectiveness of an intervention to reduce sickness absence in patients with emotional distress or minor mental disorders: a randomized controlled effectiveness trial.

    OpenAIRE

    Brouwers, E.P.M.; Tiemens, B.G.; Terluin, B.; Verhaak, P.F.M.

    2006-01-01

    OBJECTIVE: The purpose of this study was to evaluate the effectiveness of an activating intervention designed to reduce sick leave duration in patients with emotional distress or minor mental disorders. METHOD: In a 1.5-year randomized controlled trial, 194 patients with minor mental disorders received either an experimental intervention by social workers or general practitioners' usual care. The intervention focused on understanding causes, developing and implementing problem-solving strateg...

  10. A Thirsty Nation

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Since 1950, lake areas in China have shrunk by 15 percent, and marshes by more than 25 percent. Meanwhile, water consumption has increased 500 percent, with per-capita water consumption doubling. During 2000 and 2004, China's gross water resources fell 13 percent while the per-capita amount dropped from 2,194 cubic meters to 1,856 cubic meters, down 15 percent.

  11. Impacts of chronic low-level nicotine exposure on Caenorhabditis elegans reproduction: Identification of novel gene targets

    OpenAIRE

    Michael A Smith; Zhang, Yanqiong; Polli, Joseph R.; Wu, Hongmei; Zhang, Baohong; Xiao, Peng; Farwell, Mary A.; Pan, Xiaoping

    2013-01-01

    Effects and mechanisms of chronic exposure to low levels of nicotine is an area fundamentally important however less investigated. We employed the model organism Caenorhabditis elegans to investigate potential impacts of chronic (24 h) and low nicotine exposure (6.17–194.5 μM) on stimulus-response, reproduction, and gene expressions. Nicotine significantly affects the organism's response to touch stimulus (p = 0.031), which follows a dose-dependent pattern. Chronic nicotine exposure promotes ...

  12. Application of Grouted Micropile in Old Road Consolidation%注浆微型桩在旧路补强中的应用

    Institute of Scientific and Technical Information of China (English)

    张继彬

    2015-01-01

    结合G308公路K605 +595~K609+ 194(青岛方向)路段病害,分析了造成局部弯沉值不合格的原因,提出病害处治方案.通过注浆微型桩实施前后病害路弯沉检测对比,对压力注浆效果进行评价.

  13. Effect of aluminum content on the passivation behavior of Fe-Al alloys in sulfuric acid solution

    DEFF Research Database (Denmark)

    Chiang, Wen-Chi; Luu, W.C.; Wu, J.K.

    2006-01-01

    The passivation behavior of Fe-Al alloys (3.4, 10.4, 18.7, 19.4, 29.5, and 41.7 at % Al) and Fe-Al alloys (19.5 and 29.0 at % Al) with 5.1 at % Cr addition in 0.1 N H2SO4 is reported in this paper. The behavior has been evaluated by potentiodynamic polarization measurements. The results show the ...

  14. Mass Spectral Library, NIST '02 With Windows 2.0 Software

    Science.gov (United States)

    SRD 1A NIST/EPA/NIH Mass Spectral Library, NIST '02 With Windows 2.0 Software (PC database for purchase)   Available with full-featured NIST MS Search Program for Windows integrated tools, the NIST '98 is a fully evaluated collection of electron-ionization mass spectra. (147,198 Compounds with Spectra; 147,194 Chemical Structures; 174,948 Spectra )

  15. Analisis Reaksi Pasar Terhadap Penerapan International Financial Reporting Standard (IFRS) Pada Perusahaan Manufaktur Yang Terdaftar di Bursa Efek Indonesia dan di Bursa Malaysia 2012

    OpenAIRE

    Manalu, Yudistira Tumbur Saputra

    2015-01-01

    This research is aimed to analyze the market reaction towards the adoption of International Financial Reporting Standard (IFRS) at manufacture company listed on Indonesia Stock Exchange, and Bursa Malaysia 2012. The population of this research are 139 manufacture companies in Indonesia and 194 manufacture companies in Malaysia with access the financial statement on website www.idx.co.id and www.bursamalaysia.com. Sampling method that used in this research is purposive sampling method, so I...

  16. Family Obligation Values as a Protective and Vulnerability Factor among Low-Income Adolescent Girls

    OpenAIRE

    Milan, Stephanie; Wortel, Sanne

    2014-01-01

    Adolescents’ beliefs about family obligation often reflect cultural variations in their family context, and thus are important for understanding development among diverse youth. In this study, we test hypotheses about the role of family obligation values in risk behavior and mental health in a sample of 194 low-income adolescent girls (Mean age = 15.2; 58% Latina, 28% African-American/Black). We hypothesized that family obligation values can be both a protective and vulnerability factor, depe...

  17. Relationship among Strategy, Flexibility, & Performance in the Supply Chain of the Iranian Automotive Industry

    OpenAIRE

    Khademolomoom, Amir Hossein; Emeagwali, Okechukwu Lawrence

    2016-01-01

    Despite the breadth of research devoted to supply chain management, no study has comprehensively probed into this issue with respect to a single sector in the specific context of the Middle East. To address this deficiency, this research investigates the relationship among strategy, flexibility, and performance in the supply chain context of the automotive industry in Iran. A quantitative questionnaire survey was administered to194Iranian automotive SMEs, and the results were examined by path...

  18. [Case of anti VGKC-complex antibody associated disorder presenting with severe pain and fasciculations predominant in unilateral upper extremity].

    Science.gov (United States)

    Hara, Kenju; Watanabe, Osamu; Shibano, Ken; Ishiguro, Hideaki

    2012-01-01

    A 21-year-old man complained of severe pain and muscle twitching localized in his right arm. Neurological examination showed muscle fasciculations in his right forearm but no myokymia or myotonia. Needle electromyography revealed fibrillation potentials in his biceps brachii muscle and extensor carpi radialis muscle at rest but no myokymic discharges. His serum anti-voltage-gated potassium channel (VGKC)-complex antibody level was significantly high (194.2pM; controls VGKC-complex antibody associated disorder.

  19. CYP2D6 genotype determination in the Danish population

    DEFF Research Database (Denmark)

    Brøsen, K; Nielsen, P N; Brusgaard, K;

    1994-01-01

    .741 (0.026) in the Danish population and the second most common allele was the D6-B with an apparent frequency of 0.194 (0.024). The median (range) of the sparteine metabolic ratio (MR) in 47 homozygous D6-wt EM was 0.28 (0.11-4.10) and the corresponding value in heterozygous EM was 0.36 (0...

  20. Magnetic resonance imaging of neuronal ceroid lipofuscinosis in a border collie.

    Science.gov (United States)

    Koie, Hiroshi; Shibuya, Hisashi; Sato, Tsuneo; Sato, Akane; Nawa, Koji; Nawa, Yuko; Kitagawa, Masato; Sakai, Manabu; Takahashi, Tomoko; Yamaya, Yoshiki; Yamato, Osamu; Watari, Toshihiro; Tokuriki, Mikihiko

    2004-11-01

    A castrated male border collie 23 months of age weighing 19.4 kg was referred to the Animal Medical Center of Nihon University with complaints of visual disturbance and behavioral abnormality, hyperacusis and morbid fear. The MRI examination revealed the slight dilated cerebral sulci and cerebellar fissures and left ventricular enlargement. This is the first report of MRI findings of canine neuronal ceroid lipofuscinosis. PMID:15585966

  1. AcEST: BP918812 [AcEST

    Lifescience Database Archive (English)

    Full Text Available KKLWSGKNTQ 609 >tr|B2CBZ1|B2CBZ1_PINEL Early response to drought 3 (Fragment) OS=Pinus elliottii GN=erd3 PE=...t 3 (Fragment) OS=Pinus elliottii GN=erd3 PE=4 SV=1 Length = 207 Score = 184 bits...193 Query: 218 CQKSFWRS 195 CQK WRS Sbjct: 194 CQKKDWRS 201 >tr|B2CBZ2|B2CBZ2_PINEL Early response to drough

  2. Levels of histamine and other biogenic amines in high quality red wines.

    OpenAIRE

    Konakovsky, Viktor; Focke, Margarete; Hoffmann-Sommergruber, Karin; Schmid, Rainer,; Scheiner, Otto; Moser, Peter; Jarisch, Reinhart; Hemmer, Wolfgang

    2011-01-01

    Abstract Biogenic amines in wine may impair sensory wine quality and cause adverse health effects in susceptible individuals. In this study, histamine and other biogenic amines were determined by HPLC after amine derivatization to dansyl chloride conjugates in 100 selected high quality red wines made from seven different cultivars. Amine levels varied considerably between different wines. The most abundant amines were putrescine (median 19.4 mg/L, range 2.9-122), histamine (7.2, 0....

  3. The Performance Effects of Congruence Between Product Competitive Strategies and Purchasing Management Design

    OpenAIRE

    Julie Smith David; Yuhchang Hwang; Buck K. W. Pei; J. Hal Reneau

    2002-01-01

    The objective of this study is to examine a performance contingency effect between product competitive strategy and organization design using an archival approach. Specifically, this study examines a sample of 194 firms from 20 industries based on the data collected by Center for Advanced Purchasing Studies (CAPS) in its benchmarking surveys between 1989-1994 and links the benchmarking data to the COMPUSTAT (Standard & Poor's) financial data of these firms. The results of the study reveal a c...

  4. DOPING IN SPORT: GLOBAL ETHICAL ISSUES

    OpenAIRE

    Angela J. Schneider; Fan Hong

    2007-01-01

    DESCRIPTION In this book the question of "How ethical is using performance improving drugs in sport?" is argued in global perspective. PURPOSE The ethical questions in sport are discussed comprehensively. Particularly, different cultures and approach of various countries to that issue were examined. FEATURES The book composed of 10 chapters following a thorough introduction from the editors in 194 pages. The titles are: 1.Fair is Fair, Or Is It? : A Moral Consideration of the Doping Wars in A...

  5. Retrieval of soil moisture and vegetation water content using SSM/I data over a corn and soybean region

    OpenAIRE

    Jiang, W; Jackson, T.J.; Bindlish, R.; Hsu, A Y; Su, Z

    2005-01-01

    The potential for soil moisture and vegetation water content retrieval using Special Sensor Microwave Imager (SSM/I) brightness temperature over a corn and soybean field region was analyzed and assessed using datasets from the Soil Moisture Experiment 2002 (SMEX02). Soil moisture retrieval was performed using a dual-polarization 19.4-GHz data algorithm that requires the specification of two vegetation parameters¿single scattering albedo and vegetation water content. Single scattering albedo w...

  6. Effect of feed supplement on Milk Production, Fat % Total Serum Protein and Minerals in Lactating Buffalo

    Directory of Open Access Journals (Sweden)

    R.K. Verma

    2009-10-01

    Full Text Available A study was carried out to see the effect of feed supplement “Khurak” on milk yielding buffalo. The buffaloes were divided in two group. One group was offered “Khurak” as feed supplement for 7 days. Significant increase was observed in milk production, Total serum protein and calcium in khurak supplemented group (Treatment group. [Vet. World 2009; 2(5.000: 193-194

  7. Characterization of an allosteric citalopram-binding site at the serotonin transporter

    DEFF Research Database (Denmark)

    Chen, Fenghua; Breum Larsen, Mads; Neubauer, Henrik Amtoft;

    2005-01-01

    -citalopram, sertraline,       serotonin and paroxetine. EC50 values for S- and R-citalopram are 3.6 +/-       0.4 microm and 19.4 +/- 2.3 microm, respectively. Fluoxetine, venlafaxine       and duloxetine have no significant effect on the dissociation of       [3H]S-citalopram. Allosteric modulation of dissociation...

  8. Detection of Perinatal Cytomegalovirus Infection and Sensorineural Hearing Loss in Belgian Infants by Measurement of Automated Auditory Brainstem Response▿

    OpenAIRE

    Verbeeck, Jannick; Van Kerschaver, Erwin; Wollants, Elke; Beuselinck, Kurt; Stappaerts, Luc; Van Ranst, Marc

    2008-01-01

    Since auditory disability causes serious problems in the development of speech and in the total development of a child, it is crucial to diagnose possible hearing impairment as soon as possible after birth. This study evaluates the neonatal hearing screening program in Flanders, Belgium. The auditory ability of 118,438 babies was tested using the automated auditory brainstem response. We selected 194 babies with indicative hearing impairment and 332 matched controls to investigate the associa...

  9. The cost-effectiveness analysis of JinQi Jiangtang tablets for the treatment on prediabetes: a randomized, double-blind, placebo-controlled, multicenter design

    OpenAIRE

    Sun, Xiao; GUO, LIPING; Shang, Hongcai; Ren, Ming; Wang, Yue; Huo, Da; Lei, Xiang; Wang, Hui; Zhai, Jingbo

    2015-01-01

    Background At present, diabetes is a chronic disease of great cost and heavy burdens. The International Diabetes Federation has repeatedly warned that by 2025, the global number of diabetics would rise to 333 million from 194 million in 2003. Although the occurrence of diabetes in developing countries is lower, China has a large population, so that the number of cases is increased. At the same time, more people have prediabetes, a growing health concern where a large percentage of the patient...

  10. GHRH|HaeIII Gene Polymorphism in Dairy and Beef Cattle at National Livestock Breeding Centers

    Directory of Open Access Journals (Sweden)

    A. O. Rini

    2013-12-01

    Full Text Available This study was aimed to identify polymorphism of growth hormone releasing hormone (GHRH gene in 89 heads of Holstein-Friesian (HF dairy cattle from Lembang Artificial Insemination Center/LAIC (17 bulls, Singosari Artificial Insemination Center/SAIC (32 bulls, and Cipelang Livestock Embryo Center/CLEC (40 cows; as well as in 4 breeds of female beef cattle from CLEC for comparison, providing Simmental (13 cows, Limousin (14 cows, Brahman (5 cows, and Angus (5 cows. This study used PCR-RFLP method by using HaeIII restriction enzyme. The enzyme cut the GHRH gene at nucleotides of GG|CC at the base positions of 118, 312, and 406 and produced 4 fragments of 118, 194, 94, and 45 bp respectively. Genotyping the GHRH gene produced two types of allele, namely A (312, 94, and 45 bp and B (194, 118, 94, and 45 bp. These two alleles resulted in three types of genotype, namely AA (312, 94, and 45 bp, AB (312, 194, 118, 94, and 45 bp, and BB (194, 118, 94, and 45 bp. Frequency of the B allele was dominant to the A allele. Chi-Square analysis showed that all of HF dairy and beef cattle observed were in Hardy-Weinberg equilibrium (X2 < X2(0.05. The highest heterozygosity value was 0.471 for HF bulls in LAIC, while the lowest one was for HF bulls in SAIC. Heterozygosity values in Simmental and Limousin cattles were higher than that of in HF cattle. The GHRH gene in HF and beef cattle was polymorphic, the exception was for Brahman with the only B allele. This result will improve the understanding of the polymorphism of GHRH gene in dairy and beef cattle.

  11. Parental authority styles in adolescent-parent relationships

    OpenAIRE

    Kuhar, Metka

    2010-01-01

    "Die Studie konfrontiert eine adaptierte Version der Family Communication Patterns (FCP) nach Ritchie/Fitzpatrick (1990) mit einer ebenfalls adaptierten Version der Psychological Control Scale nach Barber (1996). Die Analyse basiert auf einer Stichprobe von 194 Personen, erstgeborene slowenische Jugendliche und deren Eltern. Die Ergebnisse aus der Kombination von Variablen der beiden theoretisch-empirischen Kontexte verweisen auf die Bedeutung des Konzepts der elterlichen Autorität und insbes...

  12. Reduction of cardiovascular event rate: different effects of cardiac rehabilitation in CABG and PCI patients

    OpenAIRE

    Hansen, D.; DENDALE, PAUL; Leenders, M; Berger, J.; Raskin, A.; Vaes, J.; Meeusen, R.

    2009-01-01

    Objective - In coronary artery disease, the implementation of a cardiac rehabilitation (CR) programme favourably affects cardiovascular prognosis. However, it remains uncertain whether patients benefit to a similar extent from CR after coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). In this study, we have assessed whether CR is equally effective for suppressing the two-year cardiovascular event incidence after CABG or PCI. Methods and results - 194 PCI...

  13. Maternal and perinatal outcomes in critically ill obstetric patients

    Directory of Open Access Journals (Sweden)

    Arati Appinabhavi

    2014-02-01

    Conclusions: Pregnancy-induced hypertensive disorders and hemorrhage were the major risk factors apart from pneumonia and hepatitis that continue to take toll in obstetric patients. Adequate antenatal care, increased vigilance of women during pregnancy for subtle signs and symptoms, early transfer to tertiary centre and aggressive management to prevent complications can bring about the desired reduction in maternal-perinatal morbidity and mortality. [Int J Reprod Contracept Obstet Gynecol 2014; 3(1.000: 189-194

  14. 大学生のアサーション行動とソーシャル・サポート,家族関係およびハーディネスとの関連

    OpenAIRE

    加藤, 佳子; 西, 敦子; 伊藤, 海織

    2012-01-01

    Objective: With the attenuation of human relations, a decrease in communicative competence becomes problematic, and the necessity of teaching communication skills in primary- and secondary-level education rises. The aim of this study is to investigate the hypothesis that social support and family relationship affects hardiness and hardiness affect assertion behaviors.Method: 175 university students (85 men: 19.2±1.0yrs, 94 females 19.4±1.2yrs) completed a questionnaire measuring instrumental ...

  15. 大学生のアサーション行動とソーシャル・サポート,家族関係およびハーディネスとの関連

    OpenAIRE

    Kato, Yoshiko; Nishi, Atsuko; Ito, Miori

    2012-01-01

    Objective: With the attenuation of human relations, a decrease in communicative competence becomes problematic, and the necessity of teaching communication skills in primary- and secondary-level education rises. The aim of this study is to investigate the hypothesis that social support and family relationship affects hardiness and hardiness affect assertion behaviors. Method: 175 university students (85 men: 19.2±1.0yrs, 94 females 19.4±1.2yrs) completed a questionnaire measuring instrume...

  16. Las infancias que vivimos

    Directory of Open Access Journals (Sweden)

    Pablo Rodríguez Jiménez

    2014-03-01

    Full Text Available Los niños que fuimos: huellas de la infancia en Colombia. Patricia Londoño Vega y Santiago Londoño Vélez (investigación y curaduría Biblioteca Luis Ángel Arango, Banco de la República (catálogo de la exposición, Bogotá, 2012, 194 págs, il.

  17. 78 FR 73424 - Retirement of Requirements in Reliability Standards

    Science.gov (United States)

    2013-12-06

    ... Proposed Rulemaking, 78 FR 38,851 (June 28, 2013), 143 FERC ] 61,251 (2013) (NOPR), errata, 78 FR 41,339... 52 FR 47897 (Dec. 17, 1987), FERC Stats. & Regs. Regulations Preambles 1986-1990 ] 30,783 (1987). \\38... NUC-001-2, Requirements R9.1, R9.1.1, R9.1.2, R9.1.3, and R1.9.4--Nuclear Plant Interface...

  18. Evaluation of alternative intra-oral repair techniques for fractured ceramic-fused-to-metal restorations (Review)

    OpenAIRE

    Özcan, M

    2003-01-01

    Versch. in: Journal of Oral Rehabilitation 2003 30; 194–203 Ceramic fractures are serious and costly problems in dentistry. Moreover, they pose an aesthetic and functional dilemma both for the patient and the dentist. This problem has created demand for the development of practical repair options which do not necessitate the removal and remake of the entire restoration. Published literatureon repair techniques for fractured fixed partial dentures, concentrating on the data obtained both from ...

  19. Experiment list: SRX1004437 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ,47.0,0 slx4-486A-FLAG ChIP-seq - MMS - S. cerevisiae: ChIP sample strain=ABY194 || collection_date=not applicable... || geo_loc_name=not applicable || isolation_source=not applicable || genotype=slx4-486A-6his10FLAG::k...hIP || ChIP_antibody=anti-FLAG || seq_read_(paired-end)=not applicable || treatment=60 min MMS || date=07-Ma

  20. Hepatitis

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    2005226 Characteristics of peripheral blood T lymphocyte subsets in hepatitis B patients. FAN Zhen-ping(范振平),et al. Center Bio Ther, Instit Infect Dis, 302 Hosp Chin PLA, Beijing 100039. World Chin J Digestol, 2005;13(2): 194-197. Objective: To characterize the T-lymphocyte subsets in peripheral blood of patients with acute and chronic hepatitis B, and to explore their relations with the disease state. Methods: Peripheral blood

  1. Emergence of Macrolide Resistance in Throat Culture Isolates of Group A Streptococci in Ontario, Canada, in 2001

    OpenAIRE

    Katz, Kevin C.; McGeer, Allison J.; Duncan, Carla L.; Ashi-Sulaiman, Aisha; Willey, Barbara M.; Sarabia, Alicia; McCann, Jacquie; Pong-Porter, Sylvia; Rzayev, Yana; de Azavedo, Joyce S.; Low, Donald E.

    2003-01-01

    Of 500 group A streptococci isolated from pharyngeal swabs, 72 (14.4%) were macrolide resistant, compared to 2.1% in 1997. Of these, 66 (92%) were of the M phenotype and 6 (8.3%) were of the MLS phenotype. Pulsed-field gel electrophoresis found that two clones, with patterns identical to those of serotypes M1 and M4, accounted for 19.4 and 68.1% of the macrolide-resistant isolates, respectively.

  2. Фізична реабілітація хворих з переломами дистального метаепіфіза плечової кістки

    OpenAIRE

    Naumenko, Leonid; Nosivets, Dmytro

    2010-01-01

    On the basis of clinical results of treatment in 194 patients with fractures of the distal humeral metaepiphysis, the authors of the article developed a programme of physical rehabilitation. The restorative treatment consists of 4 periods: 1) preoperative, or immobilization, 2) early mobilization of the elbow joint, 3) late mobilization of the elbow joint, 4) outpatient restorative treatment. The duration of the dispensary observation averaged 55.2 months (from 7 months to 14 months after the...

  3. EST Table: FY743942 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available tein analogous to peritrophins 3-D2 [Tribolium castaneum] gb|ABL73931.1| obstractor D [Tribolium castaneum] ...R:29198983:29203672:1|gene:AGAP002909 11/11/04 84 %/194 aa gnl|Amel|GB16370-PA 11/11/04 86 %/193 aa gi|119387892|gb|ABL73931.1| obstractor D [Tribolium castaneum] FS938058 famL ...

  4. EST Table: FS923994 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available tein analogous to peritrophins 3-D2 [Tribolium castaneum] gb|ABL73931.1| obstractor D [Tribolium castaneum] ...R:29198983:29203672:1|gene:AGAP002909 10/09/10 84 %/194 aa gnl|Amel|GB16370-PA 10/09/10 86 %/193 aa gi|119387892|gb|ABL73931.1| obstractor D [Tribolium castaneum] FS938058 fwgP ...

  5. EST Table: FS922092 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available tein analogous to peritrophins 3-D2 [Tribolium castaneum] gb|ABL73931.1| obstractor D [Tribolium castaneum] ...R:29198983:29203672:1|gene:AGAP002909 10/09/10 84 %/194 aa gnl|Amel|GB16370-PA 10/09/10 86 %/193 aa gi|119387892|gb|ABL73931.1| obstractor D [Tribolium castaneum] FS938058 fwgP ...

  6. EST Table: FS923498 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available tein analogous to peritrophins 3-D2 [Tribolium castaneum] gb|ABL73931.1| obstractor D [Tribolium castaneum] ...R:29198983:29203672:1|gene:AGAP002909 10/09/10 84 %/194 aa gnl|Amel|GB16370-PA 10/09/10 86 %/193 aa gi|119387892|gb|ABL73931.1| obstractor D [Tribolium castaneum] FS938058 fwgP ...

  7. Marital conflict, respiratory sinus arrhythmia, and allostatic load: Interrelations and associations with the development of children’s externalizing behavior

    OpenAIRE

    El-Sheikh, Mona; Hinnant, J. Benjamin

    2011-01-01

    Allostatic load theory hypothesizes that stress and the body’s responses to stressors contribute to longer term physiological changes in multiple systems over time (allostasis), and that shifts in how these systems function have implications for adjustment and health. We investigated these hypotheses with longitudinal data from two independent samples (n = 413; 219 girls, 194 boys) with repeated measures at ages 8, 9, 10, and 11. Initial parental marital conflict and its change over time inde...

  8. Raman spectroscopic study of DL valine under pressure up to 20 GPa

    Science.gov (United States)

    Rêgo, F. S. C.; Lima, J. A.; Freire, P. T. C.; Melo, F. E. A.; Mendes Filho, J.; Polian, A.

    2016-04-01

    DL-valine crystal was studied by Raman spectroscopy under hydrostatic pressure using a diamond anvil cell from ambient pressure up to 19.4 GPa in the spectral range from 40 to 3300 cm-1. Modifications in the spectra furnished evidence of the occurrence of two structural phase transitions undergone by this racemic amino acid crystal. The classification of the vibrational modes, the behavior of their wavenumber as a function of the pressure and the reversibility of the phase transitions are discussed.

  9. Individual and Worksite Environmental Factors Associated with Habitual Beverage Consumption among Overweight and Obese Adults

    OpenAIRE

    Comber, Dana Lynn

    2011-01-01

    The number of overweight adults has risen to two-thirds of the population, thus increases in energy intake, particularly from beverages are of great concern. Sugar-sweetened beverage (SSB) intake has increased by 222 calories in recent decades, which contributes a significant source of added sugars to the American diet. It has been reported that water consumers have a lower overall energy intake (~194 kcals) as compared to non-consumers of water therefore substituting water for SSBs may facil...

  10. AcEST: BP911852 [AcEST

    Lifescience Database Archive (English)

    Full Text Available binding protein OS=Arabidops... 194 2e-48 tr|A9PC45|A9PC45_POPTR Putative uncharacterized protein OS=Popul... 192 1e-47 tr|A5BWR...2|A5BWR2_VITVI Putative uncharacterized protein OS=Vitis... 191 2e-47 tr|A7QW72|A7QW72_...G DE Sbjct: 121 INAEKSPFLAEKLKILVLPTLALIKNAKVDDYVVGFDE 158 >tr|A5BWR2|A5BWR2_VITVI Putative uncharacterized

  11. Nucleotide sequence of a cyanobacterial nifH gene coding for nitrogenase reductase

    OpenAIRE

    Mevarech, Moshe; Rice, Douglas; Haselkorn, Robert

    1980-01-01

    The nucleotide sequence of nifH, the structural gene for nitrogenase reductase (component II or Fe protein of nitrogenase) from the cyanobacterium Anabaena 7120 has been determined. Also reported are 194 bases of the 5′-flanking sequence and 170 bases of the 3′-flanking sequence. The predicted amino acid sequence was compared with that determined for the complete nitrogenase reductase of Clostridium pasteurianum and the cysteine-containing peptides of the protein from Azotobacter vinelandii. ...

  12. Dicty_cDB: Contig-U05010-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ap Contig length 427 Chromosome number (1..6, M) - Chromosome length - Start point - End point - Strand (PLU...5 Identities = 119/119 (100%) Strand = Plus / Plus Query: 218 catcacttaatcantnntc... bits (49), Expect = 9e-21 Identities = 52/52 (100%) Strand = Plus / Plus Query: 45 aatatttttacaatatattctaaa... Identities = 44/44 (100%) Strand = Plus / Plus Query: 151 aaaattattantnttcnnattttagtaactttgaatcaatttcc 194 ...re = 60.0 bits (30), Expect = 2e-09 Identities = 30/30 (100%) Strand = Plus / Plu

  13. Water transport by Na+-coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution

    DEFF Research Database (Denmark)

    Zeuthen, Thomas; Belhage, Bo; Zeuthen, Emil

    2005-01-01

    -analogue alpha-MDG (MW 194); using the larger sugar arbutin (MW 272) this number was reduced by a factor of at least 0.86+/-0.03 (15). For the human SGLT1 the respective numbers were 234+/-12 (18) and 0.85+/-0.8 (7). For NIS, 253+/-16 (12) water molecules were cotransported for each 2 Na+ and 1 thiocyanate (SCN...

  14. The Lebesgue decomposition theorem for arbitrary contents

    OpenAIRE

    König, Heinz

    2005-01-01

    The decomposition theorem named after Lebesgue asserts that certain set functions have canonical representations as sums of particular set functions called the absolutely continuous and the singular ones with respect to some fixed set function. The traditional versions are for the bounded measures with respect to some fixed measure on a \\sigma algebra, in final form due to Hahn 1921, and for the bounded contents with respect to some fixed content on an algebra, due to Bochner-Phillips 194...

  15. High intensity focused ultrasound vs. cryotherapy as primary treatment for prostate cancer

    OpenAIRE

    Ranjan, Pratyush; Saurabh, Gyan; Bansal, Rahul; Gupta, Amit

    2008-01-01

    Prostate cancer is one of the most commonly diagnosed cancers. Here, we will be discussing two upcoming techniques for its management. One is cryotherapy which has returned from oblivion after nearly 150 years armed with latest technology and looking as if its full potential has been recognized now. On the other hand is high intensity focused ultrasound (HIFU), the application of ultrasound to this field is relatively new and hence a lot of excitement and hope. We searched MEDLINE (PubMed 194...

  16. Composition and ecological patterns of snake assemblages in an Amazon-Cerrado Transition Zone in Brazil

    OpenAIRE

    Leandra C. Pinheiro; Pedro S. Abe; Youszef O. C. Bitar; Luiz P. P. Albarelli; Maria C. Santos-Costa

    2015-01-01

    ABSTRACT The present study encompasses the species composition and ecological characteristics of the snake community in a Cerrado-Amazon transition zone in Midwest of Brazil (state of Mato Grosso). The data were collected during six excursions to the "Tanguro" (study area) by visual encounter survey, pitfall traps with drift fences and non-systematic sampling. We collected 194 specimens, distributed in 34 species, 26 genera, and eight families. The most abundant species were Crotalus durissus...

  17. Improved method for extraction and detection of Helicobacter pylori DNA in formalin-fixed paraffin embedded gastric biopsies using laser micro-dissection

    Directory of Open Access Journals (Sweden)

    María Fernanda Loayza

    2015-01-01

    • The use of thin purification columns with 35 μL of elution buffer. The mean of DNA concentration obtained from 25 LM cut sections was 1.94± 0 .16 ng/μL, and it was efficiently amplified with qPCR in a Bio Rad iCycler instrument. The LM can improve the sample selection and DNA extraction for molecular analysis of H. pylori associated with human gastric epithelium.

  18. “Bad Romance”: Links between Psychological and Physical Aggression and Relationship Functioning in Adolescent Couples

    OpenAIRE

    Inge Seiffge-Krenke; Burk, William J.

    2015-01-01

    Assortative mating is an important issue in explaining antisocial, aggressive behavior. It is yet unclear, whether the similarity paradigm fully explains frequent displays of aggression in adolescents’ romantic relationships. In a sample of 194 romantic partner dyads, differences between female and male partners’ reports of aggression (psychological and physical) and different measures of relationship functioning (e.g., jealousy, conflicts, and the affiliative and romantic quality of the rela...

  19. The rural elderly :personal innovativeness toward housing and acceptance of nontraditional housing types

    OpenAIRE

    Kwon, Oh-Jung

    1991-01-01

    The major purpose of this study was to determine the factors which affect elderly individuals' innovativeness toward housing and factors which affect the acceptance of nontraditional housing type(s) by elderly individuals. The study analyzed data from the Southern Regional Research Project, 5-194, "Barriers and Incentives to Affordable Housing." The sample consisted of 1,878 respondents over age 55 who resided in 28 communities in seven southern states. A conceptual st...

  20. Deep inelastic reactions and isomers in neutron-rich nuclei across the perimeter of the A = 180-190 deformed region

    Directory of Open Access Journals (Sweden)

    Dracoulis G.D.

    2014-03-01

    Full Text Available Recent results on high-spin isomers populated in deep-inelastic reactions in the transitional tungsten-osmium region are outlined with a focus on 190Os, 192Os and 194Os. As well as the characterization of several two-quasinutron isomers, the 12+ and 20+ isomers in 192Os are interpreted as manifestations of maximal rotation alignment within the neutron i13/2 and possibly proton h11/2 shells at oblate deformation.

  1. Sinopec and COSCO Sign Strategic Partnership Agreement

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Sinopec and China Ocean Shipping (Group)Company (COSCO), the country's biggest shipping company, signed a framework cooperation agreement on June 18 in Beijing, under which COSCO would provide quality crude oil transport from the current 1.94 million deadweight tons. The ambitious plan was made to chter to COSCO's establishment of a long-term strategic partnership for cooperation with Sinopec, China's leading producer and supplier of petroleum products.

  2. Association between Appendicular Fat Mass and Metabolic Risk Factors

    OpenAIRE

    Park, Si Young; Kwon, Kil Young; Kim, Jung Hwan; Choi, Hyung Hwa; Han, Kun Hee; Han, Jee Hye

    2014-01-01

    Background Different regional fat depots have different effects on lipid and glucose metabolism. The purpose of this study is to examine the relationship between body fat distribution as measured by dual-energy X-ray absorptiometry (DEXA) and metabolic risk factors and to disclose whether there is any difference between groups with and without metabolic syndrome (MS). Methods A total of 292 participants (98 men, 194 women) over 19 years old underwent whole-body DEXA to evaluate body compositi...

  3. Fermi LAT detection of renewed and strong GeV activity from blazar 3C 279

    Science.gov (United States)

    Cutini, Sara

    2015-06-01

    The Large Area Telescope (LAT), one of two instruments on the Fermi Gamma-ray Space Telescope, has observed an intense gamma-ray flare from a source positionally consistent with the flat spectrum radio quasar 3C 279, also known as 3FGL J1256.1-0547 (Acero et al. 2015, APJS, 218, 23), with radio coordinates R.A.: 194.0465271 deg, Dec: -5.7893119 deg (J2000.0; Johnston et al. 1995, AJ, 110, 880).

  4. Some Problems and Solutions of Applying TBLT in a Chinese Large-sized Class

    Institute of Scientific and Technical Information of China (English)

    周尧

    2014-01-01

    This paper mainly looks into the problems of applying Task-based Language Teaching(TBLT) and possible solutions to them.TBLT is now also widely used in Chinese classrooms.It can also be called as "the Age of Task"(Johnson,2001: P.194).However,there are still some problems when TBLT is applied in China.Most of the problems are caused by the large class size and examination-oriented education in China.

  5. Violencia contra inmigrantes en Tamaulipas

    OpenAIRE

    Simón Pedro Izcara-Palacios

    2012-01-01

    Abstract: Violence against immigrants in TamaulipasMigrants in Mexico are subjected to extortions, kidnappings, rapes and killings. Tamaulipas, a state situated in the northeast of Mexico, has registered an unprecedented level of violence against migrants. In August of 2010, 72 migrants were massacred in San Fernando (Tamaulipas) and in April of 2011, 194 corpses of migrants were found in the same place. Furthermore, since 2009, rural communities in central Tamaulipas, which receive more than...

  6. A computer assisted universal design (CAUD) plug-in tool for architectural design process

    OpenAIRE

    Afacan, Yasemin

    2008-01-01

    Ankara : The Department of Interior Architecture and Environmental Design and the Institute of Economics and Social Sciences of Bilkent University, 2008. Thesis (Ph.D.) -- Bilkent University, 2008. Includes bibliographical references leaves 182-194. Managing universal design process is a highly complex and challenging design task due to its multi-parameter characteristics. It becomes even more difficult while accommodating the needs of people with diverse impairments in archite...

  7. Living in the Past: Phylogeography and Population Histories of Indo-Pacific Wrasses (Genus Halichoeres) in Shallow Lagoons versus Outer Reef Slopes

    OpenAIRE

    William B Ludt; Bernal, Moisés A.; Bowen, Brian W; Rocha, Luiz A.

    2012-01-01

    Sea level fluctuations during glacial cycles affect the distribution of shallow marine biota, exposing the continental shelf on a global scale, and displacing coral reef habitat to steep slopes on oceanic islands. In these circumstances we expect that species inhabiting lagoons should show shallow genetic architecture relative to species inhabiting more stable outer reefs. Here we test this expectation on an ocean-basin scale with four wrasses (genus Halichoeres): H. claudia (N = 194, with oc...

  8. Continuous-wave operation of a room-temperature Tm: YAP-pumped Ho: YAG laser

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    We report a continuous-wave (CW) 2.1-μm Ho:YAG laser operating at room temperature pumped by a diode-pumped 1.94-?m Tm:YAP laser.The maximum output power of 1.5 W is obtained from Ho:YAG laser,corresponding to Tm-to-Ho slope efficiency of 17.9% and diode-to-He conversion efficiency of 5.6%.

  9. 対人ストレスコーピングの効果における個人差

    OpenAIRE

    谷口, 弘一

    2013-01-01

    This study examined individual differences in the effects of interpersonal stress coping on mental health among adolescents. The respondents were 306 college students (100 males, 206 females) with a mean age of 19.4 years. They answered the Interpersonal Stress-Coping Inventory (consisting of positive relationship-oriented coping, negative relationship-oriented coping, and postponed-solution coping), measures of mental health (depression and loneliness), and measurements of individual differe...

  10. 40 CFR 268.39 - Waste specific prohibitions-spent aluminum potliners; reactive; and carbamate wastes.

    Science.gov (United States)

    2010-07-01

    ... wastes. (a) On July 8, 1996, the wastes specified in 40 CFR 261.32 as EPA Hazardous Waste numbers K156-K159, and K161; and in 40 CFR 261.33 as EPA Hazardous Waste numbers P127, P128, P185, P188-P192, P194... prohibited from land disposal. (b) On July 8, 1996, the wastes identified in 40 CFR 261.23 as D003 that...

  11. Ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage after different treatments

    OpenAIRE

    Wang, Sida; Liao, Chunyan; Liang, Shuyuan; Zhong, Danni; Liu, Junjie; Li, Zhixian

    2015-01-01

    Objective: To investigate the ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage (PIVH) after different treatments, and to evaluate the neurological outcomes of mild PIVH with Gesell Development Diagnosis Scale (GDDS). Methods: A total of 194 newborns with grade I-II PIVH were recruited, and findings of cranial ultrasound examination before and 1 month after birth were included for analysis. The echo intensity and size of the lesions were recorded. Results: There...

  12. Associations between music education, intelligence, and spelling ability in elementary school

    OpenAIRE

    Hille, Katrin; Gust, Kilian; Bitz, Urlich; Kammer, Thomas

    2011-01-01

    Musical education has a beneficial effect on higher cognitive functions, but questions arise whether associations between music lessons and cognitive abilities are specific to a domain or general. We tested 194 boys in Grade 3 by measuring reading and spelling performance, non verbal intelligence and asked parents about musical activities since preschool. Questionnaire data showed that 53% of the boys had learned to play a musical instrument. Intelligence was higher for boys playing an instru...

  13. Deep inelastic reactions and isomers in neutron-rich nuclei across the perimeter of the A = 180 - 190 deformed region

    International Nuclear Information System (INIS)

    Recent results on high-spin isomers populated in deep-inelastic reactions in the transitional tungsten-osmium region are outlined with a focus on 190Os, 192Os and 194Os. As well as the characterization of several two-quasineutron isomers, the 12+ and 20+ isomers in 192Os are interpreted as manifestations of maximal rotation alignment within the neutron i(13/2) and possibly proton h(11/2) shells at oblate deformation. (authors)

  14. The Need In Training And Retraining For TVET Teachers In Malaysia

    OpenAIRE

    Mimi Mohaffyza Mohamad; Muhammad Sukri Saud; Adnan Ahmad

    2009-01-01

    Malaysia is a fast developing country and to support the growth of Malaysia industrial sector Malaysia needs highly skilled workforce. To fulfill this needs Malaysia has developed many vocational and technical training institutes. Currently there are approximately 194 technical-vocational institutions and there is a plan to increase this number during five next year plan. They are 90 technical schools which provide the vocational course in secondary school level. The Technical and Vocational ...

  15. Evaluation of specific humoral immune response in pigs vaccinated with cell culture adapted classical swine fever vaccine

    OpenAIRE

    Nath, Mrinal K.; Sarma, D. K.; B. C. DAS; Deka, P.; Kalita, D.; Dutta, J. B.; Mahato, G.; S Sarma; Roychoudhury, P

    2016-01-01

    Aim: To determine an efficient vaccination schedule on the basis of the humoral immune response of cell culture adapted live classical swine fever virus (CSFV) vaccinated pigs and maternally derived antibody (MDA) in piglets of vaccinated sows. Materials and Methods: A cell culture adapted live CSFV vaccine was subjected to different vaccination schedule in the present study. Serum samples were collected before vaccination (day 0) and 7, 14, 28, 42, 56, 180, 194, 208, 270, 284 and 298 days af...

  16. Susceptibility to peer pressure and attachment to friends

    OpenAIRE

    Lotar-Rihtarić Martina; Kamenov Željka

    2013-01-01

    The role of attachment to friends in the explanation of adolescents’ susceptibility to peer pressure was explored, regarding the way these two constructs are measured. In Study 1, 475 high school students (194 boys and 281 girls) were given Susceptibility to Peer Pressure Questionnaire, and their attachment to friends was measured with Modified Experiences in Close Relationships Inventory and Relationship Scales Questionnaire. One month later, 80 boys and 80 girls participated in Study ...

  17. Announcement by the Internal Transport Service

    CERN Multimedia

    2015-01-01

    The Shipping Service requests all users of wooden pallets, freight containers and lids that are no longer in use to contact the Internal Transport Service of the GS department (George Truelove), which is responsible for collecting and returning them to the Goods Reception Service in Buildings 904 and 194. Please also contact Mr. Truelove if you receive an order that is not meant for you. Internal Transport Service

  18. Association of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Elements with Specific Serotypes and Virulence Potential of Shiga Toxin-Producing Escherichia coli

    OpenAIRE

    Toro, Magaly; Cao, Guojie; Ju, Wenting; Allard, Marc; Barrangou, Rodolphe; Zhao, Shaohua; Brown, Eric; Meng, Jianghong

    2014-01-01

    Shiga toxin-producing Escherichia coli (STEC) strains (n = 194) representing 43 serotypes and E. coli K-12 were examined for clustered regularly interspaced short palindromic repeat (CRISPR) arrays to study genetic relatedness among STEC serotypes. A subset of the strains (n = 81) was further analyzed for subtype I-E cas and virulence genes to determine a possible association of CRISPR elements with potential virulence. Four types of CRISPR arrays were identified. CRISPR1 and CRISPR2 were pre...

  19. Solariums in Norway; Solarier i Norge

    Energy Technology Data Exchange (ETDEWEB)

    Aalerud, T.N.; Nilsen, L.T.N.; Hannevik, M.

    2011-07-01

    The report presents the results from a large survey of solariums performed by the NRPA in 2008. 410 solariums in different parts of the country were inspected, and the UV radiation was measured in 194 of these. The main reason for the survey was to check the compliance with regulations, compare with earlier surveys and check the effect of inspections by local authorities.(Author)

  20. Sexuality and Affection among Elderly German Men and Women in Long-Term Relationships: Results of a Prospective Population-Based Study

    OpenAIRE

    Britta Müller; Nienaber, Christoph A.; Olaf Reis; Peter Kropp; Wolfgang Meyer

    2014-01-01

    Satisfaction with sexual activity i.e. sexual satisfaction and the importance of sexuality and affection were analysed using data from the German "Interdisciplinary Longitudinal Study of Adult Development" (ILSE). At three measurement points, 1993-1995, 1997-1998, and 2004-2006 i.e. subjects' ages of 63, 67, and 74 years, participants' reports about their affection and sexual activity were collected. The sample of completed records used for this study consisted of 194 urban non-institutionali...