WorldWideScience

Sample records for astatine 193

  1. Astatine-211: production and availability.

    Science.gov (United States)

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production.

  2. 49 CFR 193.2305-193.2319 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false 193.2305-193.2319 Section 193.2305-193.2319 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  3. 49 CFR 193.2323-193.2329 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false 193.2323-193.2329 Section 193.2323-193.2329 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  4. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    CERN Document Server

    Rothe, S; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yu; Köster, U; Lane, J; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of smallest quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.317510(8) eV. New ab initio calculations were performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of super-heavy element 117, the heaviest homologue of astatine.

  5. Comment: 193 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Japanese Bush Warbler Cettia diphone Cettia_diphone_L.png 193.png Takeru Nakazato (Database Center for Life...: Takeru Nakazato (Database Center for Life Science) ウグイス Cettia diphone cantans nakazato 2008/12/22 10:09:51 2010/01/14 20:05:22 ...

  6. Spectroscopy of low-lying states in neutron-deficient astatine and francium nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Jakobsson, U., E-mail: ulrjak@kth.se; Cederwall, B. [KTH, The Division of Nuclear Physics, AlbaNova University Center, SE-10691 Stockholm (Sweden); Uusitalo, J.; Auranen, K.; Badran, H.; Cox, D. M.; Grahn, T.; Greenlees, P. T.; Julin, R.; Juutinen, S.; Herzáň, A.; Konki, J.; Leino, M.; Mallaburn, M.; Pakarinen, J.; Papadakis, P.; Partanen, J.; Rahkila, P.; Sandzelius, M.; Sarén, J. [University of Jyvaskyla, Department of Physics, P.O. Box 35, FI-40014 University of Jyvaskyla (Finland); and others

    2015-10-15

    Low-lying states in neutron-deficient astatine and francium nuclei have been studied by means of in-beam and delayed spectroscopy. The 13/2{sup +} state has been observed in francium nuclei with a similar down-sloping trend as in neighbouring astatine and bismuth isotopes, as a function of decreasing neutron number. A systematic trend can also now be seen for the 1/2{sup +} state both in astatine and francium nuclei, where the level energy decreases steeply as a function of neutron number when moving further away from the neutron shell closure. This trend is very similar between astatine nuclei and their francium isotones. Moreover, shape coexistence has been observed between the 13/2{sup +} state and the spherical 9/2{sup −} ground state in {sup 203}Fr and {sup 205}Fr.

  7. Spectroscopy of 193Bi

    Directory of Open Access Journals (Sweden)

    Herzáň A.

    2014-03-01

    Full Text Available An experiment aiming to study the shape coexistence in 193Bi has been performed at the Accelerator laboratory of the University of Jyväskylä, Finland (JYFL. Many new states have been found, hugely extending the previously known level scheme of 193Bi. The Iπ=292+${I^\\pi } = {{{29} \\over 2}^ + }$ member of the πi13/2 band de-excites also to the previously, only tentatively placed long-lived isomeric state. This link determines the energy of the isomeric state to be 2260(1 keV and suggests a spin and parity of (272+$\\left( {{{{{27} \\over 2}}^ + }} \\right$. The half-life of the isomeric state was measured to be 84.4(6 µs. A level structure on top of this isomeric state was constructed. However, transition directly depopulating this state could not be identified. A superdeformed band almost identical to that present in the neighboring isotope 191Bi has been identified.

  8. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    DEFF Research Database (Denmark)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom

    2015-01-01

    and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting......To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical...

  9. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    NARCIS (Netherlands)

    Rothe, S.; Andreyev, A. N.; Antalic, S.; Borschevsky, A.; Capponi, L.; Cocolios, T. E.; De Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.; Kaldor, U.; Kudryavtsev, Yuri; Koester, U.; Lane, J. F. W.; Lassen, J.; Liberati, V.; Lynch, K. M.; Marsh, B. A.; Nishio, K.; Pauwels, D.; Pershina, V.; Popescu, L.; Procter, T. J.; Radulov, D.; Raeder, S.; Rajabali, M. M.; Rapisarda, E.; Rossel, R. E.; Sandhu, K.; Seliverstov, M. D.; Sjoedin, A. M.; Van den Bergh, P.; Van Duppen, P.; Venhart, M.; Wakabayashi, Y.; Wendt, K. D. A.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviou

  10. 49 CFR 193.2161 - Dikes, general.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Dikes, general. 193.2161 Section 193.2161...: FEDERAL SAFETY STANDARDS Design Impoundment Design and Capacity § 193.2161 Dikes, general. An outer wall of a component served by an impounding system may not be used as a dike unless the outer wall...

  11. 49 CFR 193.2517 - Purging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Purging. 193.2517 Section 193.2517 Transportation...: FEDERAL SAFETY STANDARDS Operations § 193.2517 Purging. When necessary for safety, components that could accumulate significant amounts of combustible mixtures must be purged in accordance with a procedure...

  12. 49 CFR 193.2051 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2051 Section 193.2051 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Siting Requirements § 193.2051 Scope. Each LNG facility designed,...

  13. 49 CFR 193.2701 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2701 Section 193.2701 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Personnel Qualifications and Training § 193.2701 Scope. This subpart...

  14. 49 CFR 193.2101 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2101 Section 193.2101 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Design § 193.2101 Scope. (a) Each LNG facility designed after March 31, 2000...

  15. 49 CFR 193.2901 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2901 Section 193.2901 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Security § 193.2901 Scope. This subpart prescribes requirements for security...

  16. 49 CFR 193.2301 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2301 Section 193.2301 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Construction § 193.2301 Scope. Each LNG facility constructed after March 31,...

  17. 49 CFR 193.2401 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2401 Section 193.2401 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Equipment § 193.2401 Scope. After March 31, 2000, each new, replaced,...

  18. 49 CFR 193.2501 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2501 Section 193.2501 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Operations § 193.2501 Scope. This subpart prescribes requirements for...

  19. 49 CFR 193.2601 - Scope.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 193.2601 Section 193.2601 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Maintenance § 193.2601 Scope. This subpart prescribes requirements...

  20. 49 CFR 193.2173 - Water removal.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Water removal. 193.2173 Section 193.2173...: FEDERAL SAFETY STANDARDS Design Impoundment Design and Capacity § 193.2173 Water removal. (a) Impoundment areas must be constructed such that all areas drain completely to prevent water collection....

  1. 46 CFR 193.50-5 - Classification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Classification. 193.50-5 Section 193.50-5 Shipping COAST... Details § 193.50-5 Classification. (a) Hand portable fire extinguishers and semiportable fire...) Classification Type Size Soda-acid and water, gals. Foam, gals. Carbon dioxide, lbs. Dry chemical, lbs. A II...

  2. 49 CFR 193.2067 - Wind forces.

    Science.gov (United States)

    2010-10-01

    ... fluids with a capacity of not more than 70,000 gallons, applicable wind load data in ASCE/SEI 7-05... 49 Transportation 3 2010-10-01 2010-10-01 false Wind forces. 193.2067 Section 193.2067...: FEDERAL SAFETY STANDARDS Siting Requirements § 193.2067 Wind forces. (a) LNG facilities must be...

  3. 7 CFR 4280.193 - Combined funding.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Combined funding. 4280.193 Section 4280.193... Efficiency Improvements Program Section D. Combined Funding § 4280.193 Combined funding. The requirements for... if the project meets the requirements specified in § 4280.109. (b) Funding. Funding provided...

  4. 49 CFR 193.2619 - Control systems.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Control systems. 193.2619 Section 193.2619...: FEDERAL SAFETY STANDARDS Maintenance § 193.2619 Control systems. (a) Each control system must be properly adjusted to operate within design limits. (b) If a control system is out of service for 30 days or more,...

  5. 49 CFR 193.2715 - Training: security.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Training: security. 193.2715 Section 193.2715...: FEDERAL SAFETY STANDARDS Personnel Qualifications and Training § 193.2715 Training: security. (a) Personnel responsible for security at an LNG plant must be trained in accordance with a written plan...

  6. 49 CFR 193.2709 - Security.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Security. 193.2709 Section 193.2709 Transportation...: FEDERAL SAFETY STANDARDS Personnel Qualifications and Training § 193.2709 Security. Personnel having security duties must be qualified to perform their assigned duties by successful completion of the...

  7. 46 CFR 193.30-1 - Application.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Application. 193.30-1 Section 193.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Automatic Sprinkler Systems § 193.30-1 Application. Automatic sprinkling systems shall comply...

  8. 46 CFR 193.10-15 - Piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Piping. 193.10-15 Section 193.10-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS FIRE PROTECTION EQUIPMENT Fire Main System, Details § 193.10-15 Piping. (a) All piping, valves, and fittings, shall meet...

  9. 46 CFR 193.15-15 - Piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Piping. 193.15-15 Section 193.15-15 Shipping COAST GUARD... Dioxide Extinguishing Systems, Details § 193.15-15 Piping. (a) The piping, valves, and fittings shall have a bursting pressure of not less than 6,000 pounds per square inch. (b) All piping, in nominal...

  10. 49 CFR 193.2711 - Personnel health.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Personnel health. 193.2711 Section 193.2711 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY...: FEDERAL SAFETY STANDARDS Personnel Qualifications and Training § 193.2711 Personnel health. Each...

  11. 49 CFR 193.2625 - Corrosion protection.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Corrosion protection. 193.2625 Section 193.2625...: FEDERAL SAFETY STANDARDS Maintenance § 193.2625 Corrosion protection. (a) Each operator shall determine which metallic components could, unless corrosion is controlled, have their integrity or...

  12. 32 CFR 193.3 - Policy.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 193.3 Section 193.3 National Defense... NATIONAL DEFENSE § 193.3 Policy. In order to insure that the national defense is served by adequate, safe and efficient highway transportation, it shall be the policy of the DoD to (a) integrate the...

  13. Dicty_cDB: SSC193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSC193 (Link to dictyBase) - - - Contig-U10256-1 SSC193F (Link to Original site) SSC...193F 589 - - - - - - Show SSC193 Library SS (Link to library) Clone ID SSC193 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSC1-D/SSC193Q.Seq.d/ Representative seq. ID SSC19...3F (Link to Original site) Representative DNA sequence >SSC193 (SSC193Q) /CSM/SS/SSC1-D/SSC193Q.Seq.d/ GTTGT...nce (All Frames) Frame A: vvlldnlllffkflqffvlnitqt*nknglnqkkikqrriicsfr*rtsc*ikrsf*tl* *rknwfh*kgclknhl*tiwc

  14. 27 CFR 28.193 - Export marks.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.193... Drawback Filing of Notice and Removal § 28.193 Export marks. In addition to the marks and brands required... chapter, the exporter shall mark the word “Export” on the Government side of each case or Government...

  15. 49 CFR 193.2015 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false 193.2015 Section 193.2015 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES: FEDERAL...

  16. 49 CFR 193.2509 - Emergency procedures.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Emergency procedures. 193.2509 Section 193.2509 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  17. 49 CFR 193.2303 - Construction acceptance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Construction acceptance. 193.2303 Section 193.2303 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  18. 49 CFR 193.2011 - Reporting.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Reporting. 193.2011 Section 193.2011 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  19. 49 CFR 193.2005 - Applicability.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Applicability. 193.2005 Section 193.2005 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  20. 49 CFR 193.2321 - Nondestructive tests.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Nondestructive tests. 193.2321 Section 193.2321 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  1. 49 CFR 193.2507 - Monitoring operations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Monitoring operations. 193.2507 Section 193.2507 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  2. 49 CFR 193.2505 - Cooldown.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Cooldown. 193.2505 Section 193.2505 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  3. 49 CFR 193.2503 - Operating procedures.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Operating procedures. 193.2503 Section 193.2503 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  4. 49 CFR 193.2003 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false 193.2003 Section 193.2003 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES: FEDERAL...

  5. 46 CFR 193.15-10 - Controls.

    Science.gov (United States)

    2010-10-01

    ... of discharging the system should the manual release or stop valve controls fail to operate. Each... EQUIPMENT Carbon Dioxide Extinguishing Systems, Details § 193.15-10 Controls. (a) Except as noted in § 193.15-20(b), all controls and valves for the operation of the system shall be outside the...

  6. Dicty_cDB: SFD193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFD193 (Link to dictyBase) - - - Contig-U15327-1 SFD193P (Link to Original site) SFD1...93F 586 SFD193Z 658 SFD193P 1244 - - Show SFD193 Library SF (Link to library) Clone ID SFD1...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SF/SFD1-D/SFD193Q.Seq.d/ Representative seq. ID SFD1...93P (Link to Original site) Representative DNA sequence >SFD193 (SFD193Q) /CSM/SF/SFD1-D/SFD1...alignments: (bits) Value SFD193 (SFD193Q) /CSM/SF/SFD1-D/SFD193Q.Seq.d/ 2405 0.0 SFK725 (SFK725Q) /CSM/SF/SF

  7. 49 CFR 193.2633 - Interference currents.

    Science.gov (United States)

    2010-10-01

    ...: FEDERAL SAFETY STANDARDS Maintenance § 193.2633 Interference currents. (a) Each component that is subject to electrical current interference must be protected by a continuing program to minimize...

  8. Dicty_cDB: SHD193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available iol.tsukuba.ac.jp/CSM/SH/SHD1-D/SHD193Q.Seq.d/ Representative seq. ID - (Link to Original site) Representa...tive DNA sequence >SHD193 (SHD193Q) /CSM/SH/SHD1-D/SHD193Q.Seq.d/ ATTTTATAAATATCATA

  9. Dicty_cDB: CHS193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHS193 (Link to dictyBase) - - - Contig-U16475-1 - (Link to Original site) - - CHS19...3Z 556 - - - - Show CHS193 Library CH (Link to library) Clone ID CHS193 (Link to dicty...iol.tsukuba.ac.jp/CSM/CH/CHS1-D/CHS193Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >CHS193 (CHS193Q) /CSM/CH/CHS1-D/CHS193Q.Seq.d/ XXXXXXXXXXAAATGTG...icant alignments: (bits) Value SFE223 (SFE223Q) /CSM/SF/SFE2-A/SFE223Q.Seq.d/ 1082 0.0 CHS193 (CHS193Q) /CSM/CH/CHS1-D/CHS19

  10. Dicty_cDB: VSF193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VS (Link to library) VSF193 (Link to dictyBase) - - - Contig-U15128-1 VSF193P (Link to Original site) VSF1...93F 376 VSF193Z 343 VSF193P 719 - - Show VSF193 Library VS (Link to library) Clone ID VSF1... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VS/VSF1-D/VSF193Q.Seq.d/ Representative seq. ID VSF1...93P (Link to Original site) Representative DNA sequence >VSF193 (VSF193Q) /CSM/VS/VSF1-D/VSF1... (rps17) gene, complete cds. 311 e-144 4 BG259081 |BG259081.1 602379133F1 NIH_MGC_92 Homo sapiens cDNA clone

  11. Laser photodetachment of radioactive ions: towards the determination of the electronegativity of astatine

    CERN Multimedia

    Rothe, Sebastian; Welander, Jakob Emanuel; Chrysalidis, Katerina; Day Goodacre, Thomas; Fedosseev, Valentine; Fiotakis, Spyridon; Forstner, Oliver; Heinke, Reinhard Matthias; Johnston, Karl; Kron, Tobias; Koester, Ulli; Liu, Yuan; Marsh, Bruce; Ringvall Moberg, Annie; Rossel, Ralf Erik; Seiffert, Christoph; Studer, Dominik; Wendt, Klaus; Hanstorp, Dag

    2017-01-01

    Negatively charged ions are mainly stabilized through the electron correlation effect. A measure of the stability of a negative ion is the electron affinity, which the energy gain by attaching an electron to a neutral atom. This fundamental quantity is, due to the almost general lack of bound excited states, the only atomic property that can be determined with high accuracy for negative ions. We will present the results of the first laser photodetachment studies of radioactive negative ions at CERN-ISOLDE. The photodetachment threshold for the radiogenic iodine isotope 128I was measured successfully, demonstrating the performance of the upgraded GANDALPH experimental beam line. The first detection of photo-detached astatine atoms marks a milestone towards the determination of the EA of this radioactive element.

  12. Determination of the electron affinity of astatine and polonium by laser photodetachment

    CERN Multimedia

    We propose to conduct the first electron affinity (EA) measurements of the two elements astatine (At) and polonium (Po). Collinear photo-detachment spectroscopy will allow us to measure these quantities with an uncertainty limited only by the spectral line width of the laser. We plan to use negative ion beams of the two radioactive elements At and Po, which are only accessible on-line and at ISOLDE. The feasibility of our proposed method and the functionality of the experimental setup have been demonstrated at ISOLDE in off-line tests by the clear observation of the photo-detachment threshold for stable iodine. This proposal is based on our Letter of Intent I-148.

  13. Advanced processes for 193-nm immersion lithography

    CERN Document Server

    Wei, Yayi

    2009-01-01

    This book is a comprehensive guide to advanced processes and materials used in 193-nm immersion lithography (193i). It is an important text for those new to the field as well as for current practitioners who want to broaden their understanding of this latest technology. The book can be used as course material for graduate students of electrical engineering, material sciences, physics, chemistry, and microelectronics engineering and can also be used to train engineers involved in the manufacture of integrated circuits. It provides techniques for selecting critical materials (topcoats, photoresi

  14. New supersymmetric quartet of nuclei: 192Os, 193Os, 193Ir, 194Ir

    CERN Document Server

    Bijker, R; Frank, A; Graw, G; Hertenberger, R; Jolie, J; Wirth, H -F

    2008-01-01

    We present evidence of the existence of a new supersymmetric quartet of nuclei in the A=190 mass region. The analysis is based on new experimental information on the odd-odd nucleus 194Ir from transfer and capture reactions. The new data allow the identification of a new supersymmetric quartet, consisting of the 192,193Os and 193,194Ir nuclei. We make explicit predictions fo r193Os, and suggest that its spectroscopic properties be measured in dedicated experiments. Finally, we study correlations between different transfer reactions.

  15. Dicty_cDB: SSI193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI193 (Link to dictyBase) - - - Contig-U14703-1 SSI193Z (Link to Original si...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSI1-D/SSI193Q.Seq.d/ Representative seq. ID SSI193Z (Link to Original si... mitochondrial 4.0 %: vacuolar 4.0 %: vesicles of secretory system >> prediction for SSI193 is cyt 5' end se...te) - - SSI193Z 630 - - - - Show SSI193 Library SS (Link to library) Clone ID SSI193 (Link to... dictyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U14703-1 Original site URL http://dict

  16. 49 CFR 193.2187 - Nonmetallic membrane liner.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Nonmetallic membrane liner. 193.2187 Section 193... GAS FACILITIES: FEDERAL SAFETY STANDARDS Design Lng Storage Tanks § 193.2187 Nonmetallic membrane liner. A flammable nonmetallic membrane liner may not be used as an inner container in a storage tank....

  17. 49 CFR 193.2615 - Isolating and purging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Isolating and purging. 193.2615 Section 193.2615...: FEDERAL SAFETY STANDARDS Maintenance § 193.2615 Isolating and purging. (a) Before personnel begin... component must be purged in accordance with a procedure which meets the requirements of AGA...

  18. 46 CFR 193.15-20 - Carbon dioxide storage.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Carbon dioxide storage. 193.15-20 Section 193.15-20... PROTECTION EQUIPMENT Carbon Dioxide Extinguishing Systems, Details § 193.15-20 Carbon dioxide storage. (a...), consisting of not more than 300 pounds of carbon dioxide, may have cylinders located within the...

  19. 49 CFR 193.2623 - Inspecting LNG storage tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Inspecting LNG storage tanks. 193.2623 Section 193.2623 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS... GAS FACILITIES: FEDERAL SAFETY STANDARDS Maintenance § 193.2623 Inspecting LNG storage tanks. Each...

  20. 49 CFR 193.2635 - Monitoring corrosion control.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Monitoring corrosion control. 193.2635 Section 193... GAS FACILITIES: FEDERAL SAFETY STANDARDS Maintenance § 193.2635 Monitoring corrosion control. Corrosion protection provided as required by this subpart must be periodically monitored to give...

  1. 49 CFR 193.2631 - Internal corrosion control.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Internal corrosion control. 193.2631 Section 193... GAS FACILITIES: FEDERAL SAFETY STANDARDS Maintenance § 193.2631 Internal corrosion control. Each component that is subject to internal corrosive attack must be protected from internal corrosion by—...

  2. 49 CFR 193.2304 - Corrosion control overview.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Corrosion control overview. 193.2304 Section 193... GAS FACILITIES: FEDERAL SAFETY STANDARDS Construction § 193.2304 Corrosion control overview. (a... materials specifications from a corrosion control viewpoint and determines that the materials involved...

  3. Ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and ionic radii of element Uus (Z = 117) and astatine.

    Science.gov (United States)

    Chang, Zhiwei; Li, Jiguang; Dong, Chenzhong

    2010-12-30

    Multiconfiguration Dirac-Fock (MCDF) method was employed to calculate the first five ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and radii for the element Uus and its homologue At. Main valence correlation effects were taken into account. The Breit interaction and QED effects were also estimated. The uncertainties of calculated IPs, EAs, and IR for Uus and At were reduced through an extrapolation procedure. The good consistency with available experimental and other theoretical values demonstrates the validity of the present results. These theoretical data therefore can be used to predict some unknown physicochemical properties of element Uus, Astatine, and their compounds.

  4. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    Energy Technology Data Exchange (ETDEWEB)

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  5. 46 CFR 193.01-3 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... PROTECTION EQUIPMENT Application § 193.01-3 Incorporation by reference. (a) Certain material is incorporated... Specification for International Shore Connections for Marine Fire Applications, incorporation by reference approved for § 193.10-10. (2) (c) National Fire Protection Association (NFPA), 1 Batterymarch Park,...

  6. 49 CFR 193.2707 - Operations and maintenance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Operations and maintenance. 193.2707 Section 193... and maintenance. (a) Each operator shall utilize for operation or maintenance of components only those... operation or maintenance function; and (3) Acceptable performance on a proficiency test relevant to...

  7. 49 CFR 193.2017 - Plans and procedures.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Plans and procedures. 193.2017 Section 193.2017 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS...

  8. 49 CFR 192.193 - Valve installation in plastic pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Valve installation in plastic pipe. 192.193... Components § 192.193 Valve installation in plastic pipe. Each valve installed in plastic pipe must be designed so as to protect the plastic material against excessive torsional or shearing loads when the...

  9. 7 CFR 3015.193 - Other non-profit organizations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Other non-profit organizations. 3015.193 Section 3015.193 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL... non-profit organizations. (a) OMB Circular No. A-122, including any subsequent amendments to...

  10. 49 CFR 193.2019 - Mobile and temporary LNG facilities.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Mobile and temporary LNG facilities. 193.2019... LIQUEFIED NATURAL GAS FACILITIES: FEDERAL SAFETY STANDARDS General § 193.2019 Mobile and temporary LNG facilities. (a) Mobile and temporary LNG facilities for peakshaving application, for service...

  11. 49 CFR 193.2627 - Atmospheric corrosion control.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Atmospheric corrosion control. 193.2627 Section... LIQUEFIED NATURAL GAS FACILITIES: FEDERAL SAFETY STANDARDS Maintenance § 193.2627 Atmospheric corrosion... atmospheric corrosion by— (a) Material that has been designed and selected to resist the corrosive...

  12. An all-solid state laser system for the laser ion source RILIS and in-source laser spectroscopy of astatine at ISOLDE, CERN

    CERN Document Server

    Rothe, Sebastian; Nörtershäuser, W

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at ISOLDE, CERN, by the addition of an all-solid state tuneable titanium: sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE, CERN, and at ISAC, TRIUMF, radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  13. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, Sebastian

    2012-09-24

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  14. Radiobiological Effects of Alpha-Particles from Astatine-211: From DNA Damage to Cell Death

    Energy Technology Data Exchange (ETDEWEB)

    Claesson, Kristina

    2011-05-15

    In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an alpha-particle emitting radionuclide, promising for targeted radioimmunotherapy of isolated tumor cells and microscopic clusters. To improve development of safe radiotherapy using 211At it is important to increase our knowledge of the radiobiological effects in cells. During radiotherapy, both tumors and adjacent normal tissue will be irradiated and therefore, it is of importance to understand differences in the radio response between proliferating and resting cells. The aim of this thesis was to investigate effects in fibroblasts with different proliferation status after irradiation with alpha-particles from 211At or X-rays, from inflicted DNA damage, to cellular responses and biological consequences. Throughout this work, irradiation was performed with alpha-particles from 211A or X-rays. The induction and repair of double-strand breaks (DSBs) in human normal fibroblasts were investigated using pulsed-field gel electrophoresis and fragment analysis. The relative biological effectiveness (RBE) of 211At for DSB induction varied between 1.4 and 3.1. A small increase of DSBs was observed in cycling cells compared to stationary cells. The repair kinetics was slower after 211At and more residual damage was found after 24 h. Comparison between cells with different proliferation status showed that the repair was inefficient in cycling cells with more residual damage, regardless of radiation quality. Activation of cell cycle arrests was investigated using immunofluorescent labeling of the checkpoint kinase Chk2 and by measuring cell cycle distributions with flow cytometry analysis. After alpha-particle irradiation, the average number of Chk2-foci was larger and the cells had a more affected cell cycle progression for several weeks compared with X-irradiated cells, indicating a more powerful arrest after 211At

  15. 49 CFR 193.2013 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... Standard 620 “Design and Construction of Large, Welded, Low-Pressure Storage Tanks” (11th edition February... FEM3A for LNG Accident Consequence Analyses” (April 1997) § 193.2059. F. National Fire...

  16. 34 CFR 300.193 - Request to show cause.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Request to show cause. 300.193 Section 300.193... show cause. An SEA, LEA or other public agency in receipt of a notice under § 300.192 that seeks an opportunity to show cause why a by-pass should not be implemented must submit a written request for a...

  17. Mir193b-365 is essential for brown fat differentiation.

    Science.gov (United States)

    Sun, Lei; Xie, Huangming; Mori, Marcelo A; Alexander, Ryan; Yuan, Bingbing; Hattangadi, Shilpa M; Liu, Qingqing; Kahn, C Ronald; Lodish, Harvey F

    2011-07-10

    Mammals have two principal types of fat. White adipose tissue primarily serves to store extra energy as triglycerides, whereas brown adipose tissue is specialized to burn lipids for heat generation and energy expenditure as a defence against cold and obesity. Recent studies have demonstrated that brown adipocytes arise in vivo from a Myf5-positive, myoblastic progenitor by the action of Prdm16 (PR domain containing 16). Here, we identified a brown-fat-enriched miRNA cluster, MiR-193b-365, as a key regulator of brown fat development. Blocking miR-193b and/or miR-365 in primary brown preadipocytes markedly impaired brown adipocyte adipogenesis by enhancing Runx1t1 (runt-related transcription factor 1; translocated to, 1) expression, whereas myogenic markers were significantly induced. Forced expression of Mir193b and/or Mir365 in C2C12 myoblasts blocked the entire programme of myogenesis, and, in adipogenic conditions, miR-193b induced myoblasts to differentiate into brown adipocytes. Mir193b-365 was upregulated by Prdm16 partially through Pparα. Our results demonstrate that Mir193b-365 serves as an essential regulator for brown fat differentiation, in part by repressing myogenesis.

  18. Identical Bands and Alignment in 193,194Tl

    Institute of Scientific and Technical Information of China (English)

    HE Xiao-Tao; YU Shao-Ying; LIU Shu-Xin; LIU Yan-Xin; ZHAO En-Guang

    2004-01-01

    @@ The microscopic mechanism of the identical bands in odd odd nucleus 194Tl and its neighbour odd-A nucleus 193Tl are investigated using the particle-number conserving method with monopole and quadrupole pairing interaction.It is found that the blocking effect plays an important role in the variation of moments of inertia (J(1) and J(2))with rotational frequency for the superdeformed bands and identical bands. The alignment of 194Tl bands with respect to the 193 Tl(1) band used as a reference is also discussed.

  19. 49 CFR 193.2515 - Investigations of failures.

    Science.gov (United States)

    2010-10-01

    ... GAS FACILITIES: FEDERAL SAFETY STANDARDS Operations § 193.2515 Investigations of failures. (a) Each operator shall investigate the cause of each explosion, fire, or LNG spill or leak which results in: (1... operational or safety reasons, they must not be removed from the plant site and must be maintained intact...

  20. 49 CFR 193.2713 - Training: operations and maintenance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Training: operations and maintenance. 193.2713... Training: operations and maintenance. (a) Each operator shall provide and implement a written plan of initial training to instruct— (1) All permanent maintenance, operating, and supervisory personnel—...

  1. 49 CFR 193.2001 - Scope of part.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES... LNG facilities used in the transportation of gas by pipeline that is subject to the pipeline safety... 49 Transportation 3 2010-10-01 2010-10-01 false Scope of part. 193.2001 Section...

  2. 49 CFR 193.2181 - Impoundment capacity: LNG storage tanks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Impoundment capacity: LNG storage tanks. 193.2181... Impoundment capacity: LNG storage tanks. Each impounding system serving an LNG storage tank must have a minimum volumetric liquid impoundment capacity of: (a) 110 percent of the LNG tank's maximum...

  3. 27 CFR 24.193 - Conversion into still wine.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Conversion into still wine..., DEPARTMENT OF THE TREASURY LIQUORS WINE Production of Effervescent Wine § 24.193 Conversion into still wine. Sparkling wine or artificially carbonated wine may be dumped for use as still wine. The dumping process...

  4. 10 CFR 431.193 - Test procedures for measuring energy consumption of distribution transformers.

    Science.gov (United States)

    2010-01-01

    ... distribution transformers. 431.193 Section 431.193 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Distribution Transformers Test Procedures § 431.193 Test procedures for measuring energy consumption of distribution transformers. The...

  5. Advances in 193 nm excimer lasers for mass spectrometry applications

    Science.gov (United States)

    Delmdahl, Ralph; Esser, Hans-Gerd; Bonati, Guido

    2016-03-01

    Ongoing progress in mass analysis applications such as laser ablation inductively coupled mass spectrometry of solid samples and ultraviolet photoionization mediated sequencing of peptides and proteins is to a large extent driven by ultrashort wavelength excimer lasers at 193 nm. This paper will introduce the latest improvements achieved in the development of compact high repetition rate excimer lasers and elaborate on the impact on mass spectrometry instrumentation. Various performance and lifetime measurements obtained in a long-term endurance test over the course of 18 months will be shown and discussed in view of the laser source requirements of different mass spectrometry tasks. These sampling type applications are served by excimer lasers delivering pulsed 193 nm output of several mJ as well as fast repetition rates which are already approaching one Kilohertz. In order to open up the pathway from the laboratory to broader market industrial use, sufficient component lifetimes and long-term stable performance behavior have to be ensured. The obtained long-term results which will be presented are based on diverse 193 nm excimer laser tube improvements aiming at e.g. optimizing the gas flow dynamics and have extended the operational life the laser tube for the first time over several billion pulses even under high duty-cycle conditions.

  6. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  7. High index fluoride materials for 193nm immersion lithography

    Science.gov (United States)

    Nawata, T.; Inui, Y.; Masada, I.; Nishijima, E.; Satoh, H.; Fukuda, T.

    2006-03-01

    We tried to investigate various kinds of metal fluoride materials which have higher gravity than CaF II and cubic crystal system, and we found out barium lithium fluoride (BaLiF 3) and potassium yttrium fluoride (KY 3F 10) as candidates for the last lens material. We have developed unique Czochralski (CZ) machines and techniques for the growth of large calcium fluoride single crystals. And we applied these technologies to the growth of fluoride high index materials. We have succeeded to grow the large BaLiF 3 single crystal with 120mm in diameter and a KY 3F 10 single crystal, and measured their basic properties such as refractive index, VUV transmittance, birefringence, and so on. As a result of our basic research, we found out that BaLiF 3 single crystal is transparent at VUV region, and the refractive index at 193nm is 1.64, and KY 3F 10 single crystal has the index of 1.59 at the wavelength of 193nm which is slightly higher than fused silica. We expect that these fluoride high index materials are useful for the last lens material of the next generation immersion lithography.

  8. Study of {sup 193}Os beta{sup -} decay; Estudo do decaimento beta{sup -} do {sup 193}Os

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, Guilherme Soares

    2006-07-01

    In this work, the excited levels of {sup 193}Ir populated by the beta{sup -} decay of {sup 193}Os (T{sub 1/2} {approx} 30h) were investigated. For that purpose, {approx} 5 mg samples of 99%-enriched {sup 192}Os were irradiated under a thermal neutron flux of {approx} 10{sup 12} s{sup -1} and then analysed both using single gamma spectroscopy and a 4-detector multi parametric acquisition facility, which provided data for both a gamma gamma coincidence analysis and a directional angular correlation gamma gamma ({theta} ) study. From these data, 28 transitions were added to this decay scheme, 11 of which were previously known from nuclear reactions and 17 observed for the first time. Eight excited levels were also added to the decay scheme, 3 of which were known from nuclear reaction studies - the remaining 5 are suggested for the first time. Moreover, it was possible to confirm suspicions found in reference that the levels at 848.93 keV and 849.093 keV are indeed the same; it was also possible to confirm the existence of an excited level at 806.9 keV, which had been inferred, but not experimentally confirmed in beta decay studies to date. The angular correlation analysis allowed for the definition of the spin of the excited level at 874 keV as 5/2{sup +;} moreover, the results showed a 79% probability that the spin of the 1078 keV level is 5/2/'-, and also restricted the spin possibilities for the new excited level at 960 keV to two values (1/2 or 3/2). It was also possible to measure the multipolarity mixing ratio ({delta}{sub Ln+1}/L{sub n}) for 43 transitions - 19 of them for the first time and most of the others with a better precision than previously known. Finally, an attempt was made to understand the low-lying levels structure for this nucleus using a theoretical model, which reproduced the ground state and the two lowest-lying excited levels in {sup 193}Ir. (author)

  9. 46 CFR 193.10-90 - Installations contracted for prior to March 1, 1968.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Installations contracted for prior to March 1, 1968. 193.10-90 Section 193.10-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... contracted for prior to March 1, 1968. Installations contracted for prior to March 1, 1968, must meet...

  10. 46 CFR 193.50-90 - Vessels contracted for prior to March 1, 1968.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Vessels contracted for prior to March 1, 1968. 193.50-90... Systems, Arrangements and Details § 193.50-90 Vessels contracted for prior to March 1, 1968. (a) Vessels contracted for prior to March 1, 1968, shall meet the following requirements: (1) Except as...

  11. 34 CFR 403.193 - What are the information requirements regarding special populations?

    Science.gov (United States)

    2010-07-01

    ... populations? 403.193 Section 403.193 Education Regulations of the Offices of the Department of Education... information requirements regarding special populations? (a)(1) Each local educational agency that receives funds under Title II of the Act shall provide to students who are members of special populations...

  12. Technique for cellular microsurgery using the 193-nm excimer laser.

    Science.gov (United States)

    Palanker, D; Ohad, S; Lewis, A; Simon, A; Shenkar, J; Penchas, S; Laufer, N

    1991-01-01

    A new cell surgery technique has been developed to produce well-defined alterations in cells and tissue without detectable heating and/or other structural damage in the surroundings. The technique involves the use of an argon fluoride excimer laser, in the deep ultraviolet (UV) region of the spectrum at 193 nm, which is guided through a glass pipette filled with a positive air pressure. To demonstrate the method, holes were drilled in the zona pellucida of mouse oocytes. The diameter of the drilled hole was determined by the pipette tip size, and its depth by an energy emitted per pulse and number of pulses. Scanning electron microscopy of the drilled mouse oocytes showed uniform, round, well-circumscribed holes with sharp edges. Oocytes that had their zona pellucida drilled with this new method fertilized in vitro and developed to the blastocyst stage in a rate similar to that of control group. These results demonstrate the nonperturbing nature of this cold laser microsurgical procedure. In addition to the extension of our results for clinical in vitro fertilization purposes, such as enhancement of fertilization and embryo biopsy, there are wide-ranging possible uses of our method in fundamental and applied investigations that require submicron accuracy in cellular alteration.

  13. EUV reticle inspection with a 193nm reticle inspector

    Science.gov (United States)

    Broadbent, William; Inderhees, Gregg; Yamamoto, Tetsuya; Lee, Isaac; Lim, Phillip

    2013-06-01

    The prevailing industry opinion is that EUV Lithography (EUVL) will enter High Volume Manufacturing (HVM) in the 2015 - 2017 timeframe at the 16nm HP node. Every year the industry assesses the key risk factors for introducing EUVL into HVM - blank and reticle defects are among the top items. To reduce EUV blank and reticle defect levels, high sensitivity inspection is needed. To address this EUV inspection need, KLA-Tencor first developed EUV blank inspection and EUV reticle inspection capability for their 193nm wavelength reticle inspection system - the Teron 610 Series (2010). This system has become the industry standard for 22nm / 3xhp optical reticle HVM along with 14nm / 2xhp optical pilot production; it is further widely used for EUV blank and reticle inspection in R and D. To prepare for the upcoming 10nm / 1xhp generation, KLA-Tencor has developed the Teron 630 Series reticle inspection system which includes many technical advances; these advances can be applied to both EUV and optical reticles. The advanced capabilities are described in this paper with application to EUV die-to-database and die-to-die inspection for currently available 14nm / 2xhp generation EUV reticles. As 10nm / 1xhp generation optical and EUV reticles become available later in 2013, the system will be tested to identify areas for further improvement with the goal to be ready for pilot lines in early 2015.

  14. Inline detection of Chrome degradation on binary 193nm photomasks

    Science.gov (United States)

    Dufaye, Félix; Sippel, Astrid; Wylie, Mark; García-Berríos, Edgardo; Crawford, Charles; Hess, Carl; Sartelli, Luca; Pogliani, Carlo; Miyashita, Hiroyuki; Gough, Stuart; Sundermann, Frank; Brochard, Christophe

    2013-09-01

    193nm binary photomasks are still used in the semiconductor industry for the lithography of some critical layers for the nodes 90nm and 65nm, with high volumes and over long periods. However, these 193nm binary photomasks can be impacted by a phenomenon of chrome oxidation leading to critical dimensions uniformity (CDU) degradation with a pronounced radial signature. If not detected early enough, this CDU degradation may cause defectivity issues and lower yield on wafers. Fortunately, a standard cleaning and repellicle service at the mask shop has been demonstrated as efficient to remove the grown materials and get the photomask CD back on target.Some detection methods have been already described in literature, such as wafer CD intrafield monitoring (ACLV), giving reliable results but also consuming additional SEM time with less precision than direct photomask measurement. In this paper, we propose another approach, by monitoring the CDU directly on the photomask, concurrently with defect inspection for regular requalification to production for wafer fabs. For this study, we focused on a Metal layer in a 90nm technology node. Wafers have been exposed with production conditions and then measured by SEM-CD. Afterwards, this photomask has been measured with a SEM-CD in mask shop and also inspected on a KLA-Tencor X5.2 inspection system, with pixels 125 and 90nm, to evaluate the Intensity based Critical Dimension Uniformity (iCDU) option. iCDU was firstly developed to provide feed-forward CDU maps for scanner intrafield corrections, from arrayed dense structures on memory photomasks. Due to layout complexity and differing feature types, CDU monitoring on logic photomasks used to pose unique challenges.The selection of suitable feature types for CDU monitoring on logic photomasks is no longer an issue, since the transmitted intensity map gives all the needed information, as shown in this paper. In this study, the photomask was heavily degraded after more than 18,000 300

  15. 14 CFR 193.17 - How must design and production approval holders handle information they receive from the FAA...

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS PROTECTION OF VOLUNTARILY SUBMITTED INFORMATION § 193.17 How must design and production approval... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false How must design and production approval holders handle information they receive from the FAA under this part? 193.17 Section 193.17...

  16. 41 CFR 102-193.25 - What type of records management business process improvements should my agency strive to achieve?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What type of records management business process improvements should my agency strive to achieve? 102-193.25 Section 102-193.25...-193.25 What type of records management business process improvements should my agency strive...

  17. Development of fluoropolymer for 193nm immersion lithography

    Science.gov (United States)

    Shirota, Naoko; Takebe, Yoko; Sasaki, Takashi; Yokokoji, Osamu; Toriumi, Minoru; Masuhara, Hiroshi

    2006-03-01

    We had already developed several series of fluoropolymers, FPRs and FUGUs, having a partially fluorinated monocyclic structure and having acidic hydroxyl group, which acts as dissolution unit into alkaline solution. Then we have optimized these polymers for top-coat as the developer-soluble type in the 193nm immersion lithography. However the hydrophobicity of these polymers were a little poor due to its hydroxyl group. So we thought that the introduction of water repellent moiety into the these polymers structure is effective to improve the their hydrophobicity though the increase of water repellent unit in the polymer leads to lower dissolution rate in developer. To introduce as much as possible of hydrophobicity unit, we selected FUGU as platform, which has larger dissolution rate in developer than that of FPRs, We copolymerized FUGU with higher water-repellent component and obtained three copolymers, FUGU-CoA, FUGU-CoB, and FUGU-CoC. In this paper, we described characteristics and evaluation of these polymers. Most of these polymer showed an improvement of hydrophobicity, in particular FUGU-CoB had excellent hydrophobicity due to introduction bulky containing-fluorine group. In this study, we also investigated the interaction between the water and various polymers by using QCM method. The difference between FUGU and water repellent polymers for swelling behavior to water became clear by analysis of diffusion coefficient. We found that our new co-polymers have excellent diffusion coefficient than FUGU which was confirmed by QCM method used to evaluate water permeability and water diffusion in the materials.

  18. Establishment of PL19-3 Ⅱ -WHPC Jacket Measurement Stations%PL19-3Ⅱ-WHPC JACKET测量坐标站的建立

    Institute of Scientific and Technical Information of China (English)

    孙云虎; 张士舰

    2005-01-01

    本文论述了PL19-3Ⅱ-WHPC JACKET测量坐标站的建立过程,并简单的介绍了间接平差和条件平差两种基本的平差数学模型;重点阐述了建立坐标站的原理和PL19-3Ⅱ-WHPC JACKET的建站模型,并说明了测角、测距所用的方法.

  19. Identification of a $9/2^-$[505] isomer in the neutron-rich $^{193}$Os nucleus

    OpenAIRE

    Gao, B. S.; Zhou, X. H.; Fang, Y. D.; Zhang, Y.H.; Liu, M.L.; Wang, S C; Wang, J.G.; F. Ma; Guo, Y. X.; Wu, X. G.; He, C.Y.(China Institute of Atomic Energy, Beijing, 102413, China); Zheng, Y.; Wang, Z. M.; Yan, X. L.; Wang, Z.G.

    2013-01-01

    The neutron rich nucleus $^{193}$Os was produced in the $^{192}$Os($^{7}$Li,$^{6}$Li)$^{193}$Os reaction. An isomeric state based on the $9/2^-$[505] nilsson orbital was identified in the present work. Half-life of the isomeric state was extracted and discussed in terms of the $K$ quantum number. Level scheme built on the isomeric state was proposed based on the experimental data.

  20. A Comparison of Photoresist Resolution Metrics using 193 nm and EUV Lithography

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Juanita; Pathak, Piyush; Wallow, Thomas; LaFontaine, Bruno; Deng, Yunfei; Kim, Ryoung-han; Kye, Jongwook; Levinson, Harry; Naulleau, Patrick; Anderson, Chris

    2007-08-20

    Image blur due to chemical amplification represents a fundamental limit to photoresist performance and manifests itself in many aspects of lithographic performance. Substantial progress has been made in linking image blur with simple resolution metrics using EUV lithography. In this presentation, they examine performance of 193 nm resist and EUV resist systems using modulation transfer function, corner rounding, and other resolution metrics. In particular, they focus on cross-comparisons in which selected EUV and 193 nm resist are evaluated using both EUV and 193 nm lithography. Simulation methods linking 193 nm and EUV performance will be described as well. Results from simulation indicate that image blur in current generation 193 nm photoresists is comparable to that of many EUV resists, but that ultra-low diffusion materials designs used in very high resolution EUV resists can result in substantially lower blur. In addition to detailing correlations between EUV and 193 nm experimental methods, they discuss their utility in assessing performance needs of future generation photoresists.

  1. An automated flow system incorporating in-line acid dissolution of bismuth metal from a cyclotron irradiated target assembly for use in the isolation of astatine-211

    Energy Technology Data Exchange (ETDEWEB)

    O’Hara, Matthew J.; Krzysko, Anthony J.; Niver, Cynthia M.; Morrison, Samuel S.; Owsley, Stanley L.; Hamlin, Donald K.; Dorman, Eric F.; Scott Wilbur, D.

    2017-04-01

    Astatine-211 (211At) is a promising cyclotron-produced radionuclide being investigated for use in targeted alpha therapy of blood borne and metastatic cancers, as well as treatment of tumor remnants after surgical resections. The isolation of trace quantities of 211At, produced within several grams of a Bi metal cyclotron target, involves a complex, multi-step procedure: (1) Bi metal dissolution in strong HNO3, (2) distillation of the HNO3 to yield Bi salts containing 211At, (3) dissolution of the salts in strong HCl, (4) solvent extraction of 211At from bismuth salts with diisopropyl ether (DIPE), and (5) back-extraction of 211At from DIPE into NaOH, leading to a purified 211At product. Step (1) has been addressed first to begin the process of automating the onerous 211At isolation process. A computer-controlled Bi target dissolution system has been designed. The system performs in-line dissolution of Bi metal from the target assembly using an enclosed target dissolution block, routing the resulting solubilized 211At/Bi mixture to the subsequent process step. The primary parameters involved in Bi metal solubilization (HNO3 concentration and influent flow rate) were optimized prior to evaluation of the system performance on replicate cyclotron irradiated targets. The results indicate that the system performs reproducibly, having nearly quantitative release of 211At from irradiated targets, with cumulative 211At recoveries that follow a sigmoidal function. The predictable nature of the 211At release profile allows the user to tune the system to meet target processing requirements.

  2. The structure of {sup 193}Au within the Interacting Boson Fermion Model

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, T., E-mail: tim.thomas@ikp.uni-koeln.de [Institute for Nuclear Physics, University of Cologne, Zülpicher Straße 77, D-50937 Köln (Germany); WNSL, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States); Bernards, C. [Institute for Nuclear Physics, University of Cologne, Zülpicher Straße 77, D-50937 Köln (Germany); WNSL, Yale University, P.O. Box 208120, New Haven, CT 06520-8120 (United States); Régis, J.-M.; Albers, M.; Fransen, C.; Jolie, J.; Heinze, S.; Radeck, D.; Warr, N.; Zell, K.-O. [Institute for Nuclear Physics, University of Cologne, Zülpicher Straße 77, D-50937 Köln (Germany)

    2014-02-15

    A γγ angular correlation experiment investigating the nucleus {sup 193}Au is presented. In this work the level scheme of {sup 193}Au is extended by new level information on spins, multipolarities and newly observed states. The new results are compared with theoretical predictions from a general Interacting Boson Fermion Model (IBFM) calculation for the positive-parity states. The experimental data is in good agreement with an IBFM calculation using all proton orbitals between the shell closures at Z=50 and Z=126. As a dominant contribution of the d{sub 3/2} orbital to the wave function of the lowest excited states is observed, a truncated model of the IBFM using a Bose–Fermi symmetry is applied to the describe {sup 193}Au. Using the parameters of a fit performed for {sup 193}Au, the level scheme of {sup 192}Pt, the supersymmetric partner of {sup 193}Au, is predicted but shows a too small boson seniority splitting. We obtained a common fit by including states observed in {sup 192}Pt. With the new parameters a supersymmetric description of both nuclei is established.

  3. MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively.

    Science.gov (United States)

    Pu, Youguang; Zhao, Fangfang; Cai, Wenjing; Meng, Xianghui; Li, Yinpeng; Cai, Shanbao

    2016-04-01

    MicroRNAs have been identified as key players in the development and progression of osteosarcoma, which is the most common primary malignancy of bone. Sequencing-based miR-omic and quantitative real-time PCR analyses suggested that the expression of miR-193a-3p and miR-193a-5p was decreased by DNA methylation at their promoter region in a highly metastatic osteosarcoma cell line (MG63.2) relative to their expression in the less metastatic MG63 cell line. Further wound-healing and invasion assays demonstrated that both miR-193a-3p and miR-193a-5p suppressed osteosarcoma cell migration and invasion. Moreover, introducing miR-193a-3p and miR-193a-5p mimics into MG63.2 cells or antagomiRs into MG63 cells confirmed their critical roles in osteosarcoma metastasis. Additionally, bioinformatics prediction along with biochemical assay results clearly suggested that the secretory small GTPase Rab27B and serine racemase (SRR) were direct targets of miR-193a-3p and miR-193a-5p, respectively. These two targets are indeed involved in the miR-193a-3p- and miR-193a-5p-induced suppression of osteosarcoma cell migration and invasion. MiR-193a-3p and miR-193a-5p play important roles in osteosarcoma metastasis through down-regulation of the Rab27B and SRR genes and therefore may serve as useful biomarkers for the diagnosis of osteosarcoma and as potential candidates for the treatment of metastatic osteosarcoma.

  4. miR-193b directly targets STMN1 and inhibits the malignant phenotype in colorectal cancer

    Science.gov (United States)

    Guo, Feng; Luo, Yang; Mu, Yi-Fei; Qin, Shao-Lan; Qi, Yang; Qiu, Yi-Er; Zhong, Ming

    2016-01-01

    Accumulating evidence suggests that aberrantly expressed microRNAs (miRNAs) contribute to the initiation and progression of human cancers. However, the underlying function of miR-193b in colorectal cancer (CRC) remains largely unexplored. Herein, we demonstrate that miR-193b is significantly down-regulated in CRC tissues compared with their normal counterparts. Kaplan-Meier analysis revealed that decreased miR-193b expression was closely associated with the shorter overall survival of patients with CRC. Through gain-and loss-of-function studies, we showed that miR-193b significantly suppressed CRC cell proliferation and invasion. In addition, bioinformatics analyses and luciferase reporter assays identified Stathmin 1 (STMN1) as the direct functional target of miR-193b in CRC. Furthermore, silencing of STMN1 resulted in a phenotype similar to that observed for overexpression of miR-193b, and restoration of STMN1 expression completely rescued the inhibitory effect of miR-193b in CRC cells. Taken together, our study implies the essential role of miR-193b in negatively regulating CRC progression, and a novel link between miR-193b and STMN1 in CRC. PMID:27904764

  5. Yeast Interacting Proteins Database: YJR055W, YPL193W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the...L193W Prey gene name RSA1 Prey description Protein involved in the assembly of 60S ribosomal subunits; functionally

  6. 46 CFR 193.15-90 - Installations contracted for prior to March 1, 1968.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Installations contracted for prior to March 1, 1968. 193...-90 Installations contracted for prior to March 1, 1968. (a) Installations contracted for prior to March 1, 1968, shall meet the following requirements: (1) Existing arrangements, materials,...

  7. 生防菌SF-193对空心莲子草防除效果及其影响因子的研究%Biocontrol Efficacy and Impact Factors of Indigenous Fungi SF-193 to Alternanthera philoxeroides

    Institute of Scientific and Technical Information of China (English)

    王晓艳; 陈志谊; 刘永锋; 李永丰; 刘邮洲

    2007-01-01

    在室内控制条件下,测定了SF-193菌株培养液对空心莲子草的致病力;在田间小区试验的条件下,测定了SF-193对空心莲子草的防除效果,以及不同因子对SF-193除草效果的影响程度.结果表明,SF-193培养3~5d的培养液具有最强的致病力;最佳接种体为含有菌丝体的培养液;田间有效接种浓度为10倍稀释液,室内有效接种浓度为25倍稀释液;适宜SF-193对空心莲子致病的最佳温度为25~30℃;高湿条件下SF-193致病过程加快.SF-193对不同生长季节和不同生境下的空心莲子草均有较好的防除效果.

  8. Product energy distributions from the 193 nm photodissociation of NH 3

    Science.gov (United States)

    Koplitz, B.; Xu, Z.; Wittig, C.

    1987-07-01

    Product energy distributions are reported for 193 nm NH 3 photodissociation. Velocity-aligned Doppler spectroscopy on the H-atom fragment reveals a "cold" kinetic energy distribution, indicating a high degree of NH 2 internal excitation. Data are compared with the trajectory calculations of Rice, Raff and Thompson for NH 3(X˜ 1A 1) dissociation, and the reaction mechanism of Ashfold, Bennett and Dixon is discussed.

  9. [Flow cytometric analysis of ICRF-193 influence on cell passage through mitosis].

    Science.gov (United States)

    Shatrova, A N; Aksenov, N D; Zenin, V V

    2002-01-01

    Studying the effect of topoisomerase II (topo II) inhibitors on cell passage through mitosis seems to be important for understanding the role of this enzyme during chromosome condensation and segregation. A flow cytometric assay (Zenin et al., 2001) allowed to determine the mitotic index, and to discriminate between not only cells in G2 and M phases (including metaphase and anaphase cells), but also cells in pseudo-G1 with 4c DNA content. It is shown that topo II catalytic inhibitor ICRF-193 blocks G2-M transition in a lymphoblastoid cell line GM-130. Addition of caffeine to cells abrogated a block of their entering mitosis but not the inhibitor action. Cells entered mitosis, which was proven by the presence of chromosomes in the examined specimen, and, bypassing anaphase, appeared in pseudo-G1 with 4c DNA content. We have found that in the presence of ICRF-193 cells, GM-130 and Hep-2 lines, previously blocked by nocodazole when in mitosis and then washed, pass through metaphase, enter anaphase and leave it to pass to pseudo-G1 with the 4c DNA content. Thus, by inhibiting topo II activity ICRF-193 causes abnormal mitotic transition.

  10. miR-193b Modulates Resistance to Doxorubicin in Human Breast Cancer Cells by Downregulating MCL-1

    Directory of Open Access Journals (Sweden)

    Jingpei Long

    2015-01-01

    Full Text Available MicroRNAs (miRNAs family, which is involved in cancer development, proliferation, apoptosis, and drug resistance, is a group of noncoding RNAs that modulate the expression of oncogenes and antioncogenes. Doxorubicin is an active cytotoxic agent for breast cancer treatment, but the acquisition of doxorubicin resistance is a common and critical limitation to cancer therapy. The aim of this study was to investigate whether miR-193b mediated the resistance of breast cancer cells to doxorubicin by targeting myeloid cell leukemia-1 (MCL-1. In this study, we found that miR-193b levels were significantly lower in doxorubicin-resistant MCF-7 (MCF-7/DOXR cells than in the parental MCF-7 cells. We observed that exogenous miR-193b significantly suppressed the ability of MCF-7/DOXR cells to resist doxorubicin. It demonstrated that miR-193b directly targeted MCL-1 3′-UTR (3′-Untranslated Regions. Further studies indicated that miR-193b sensitized MCF-7/DOXR cells to doxorubicin through a mechanism involving the downregulation of MCL-1. Together, our findings provide evidence that the modulation of miR-193b may represent a novel therapeutic target for the treatment of breast cancer.

  11. Photodissociation of HCl at 193.3 nm: Spin-orbit branching ratio

    Science.gov (United States)

    Zhang, J.; Dulligan, M.; Wittig, C.

    1997-08-01

    HCl was photodissociated by ultraviolet (uv) radiation at 193.3 nm. Time-of-flight spectra of the hydrogen atom fragment provided the spin-orbit state distribution of the chlorine fragment, [Cl(2P1/2)]/[Cl(2P3/2)]=0.69±0.02, in excellent agreement with recent theoretical studies. The H atom angular distribution studied by changing the uv photolysis laser polarization confirmed a dominant A 1Π←X 1Σ+ electronic transition in the photoexcitation process (β=-1.01±0.04 and β*=-0.94±0.07).

  12. Chemical trimming overcoat: an enhancing composition and process for 193nm lithography

    Science.gov (United States)

    Liu, Cong; Rowell, Kevin; Joesten, Lori; Baranowski, Paul; Kaur, Irvinder; Huang, Wanyi; Leonard, JoAnne; Jeong, Hae-Mi; Im, Kwang-Hwyi; Estelle, Tom; Cutler, Charlotte; Pohlers, Gerd; Yin, Wenyan; Fallon, Patricia; Li, Mingqi; Jeon, Hyun; Xu, Cheng Bai; Trefonas, Pete

    2016-03-01

    As the critical dimension of devices is approaching the resolution limit of 193nm photo lithography, multiple patterning processes have been developed to print smaller CD and pitch. Multiple patterning and other advanced lithographic processes often require the formation of isolated features such as lines or posts by direct lithographic printing. The formation of isolated features with an acceptable process window, however, can pose a challenge as a result of poor aerial image contrast at defocus. Herein we report a novel Chemical Trimming Overcoat (CTO) as an extra step after lithography that allows us to achieve smaller feature size and better process window.

  13. 193nm immersion lithography for high-performance silicon photonic circuits

    Science.gov (United States)

    Selvaraja, Shankar K.; Winroth, Gustaf; Locorotondo, Sabrina; Murdoch, Gayle; Milenin, Alexey; Delvaux, Christie; Ong, Patrick; Pathak, Shibnath; Xie, Weiqiang; Sterckx, Gunther; Lepage, Guy; Van Thourhout, Dries; Bogaerts, Wim; Van Campenhout, Joris; Absil, Philippe

    2014-04-01

    Large-scale photonics integration has been proposed for many years to support the ever increasing requirements for long and short distance communications as well as package-to-package interconnects. Amongst the various technology options, silicon photonics has imposed itself as a promising candidate, relying on CMOS fabrication processes. While silicon photonics can share the technology platform developed for advanced CMOS devices it has specific dimension control requirements. Though the device dimensions are in the order of the wavelength of light used, the tolerance allowed can be less than 1% for certain devices. Achieving this is a challenging task which requires advanced patterning techniques along with process control. Another challenge is identifying an overlapping process window for diverse pattern densities and orientations on a single layer. In this paper, we present key technology challenges faced when using optical lithography for silicon photonics and advantages of using the 193nm immersion lithography system. We report successful demonstration of a modified 28nm- STI-like patterning platform for silicon photonics in 300mm Silicon-On-Insulator wafer technology. By careful process design, within-wafer CD variation (1sigma) of 20 % from the best propagation loss reported for this cross-section fabricated using e-beam lithography. By using a single-mode low-confinement waveguide geometry the loss is further reduced to ~0.12 dB/cm. Secondly, we present improvement in within-device phase error in wavelength selective devices, a critical parameter which is a direct measure of line-width uniformity improvement due to the 193nm immersion system. In addition to these superior device performances, the platform opens scenarios for designing new device concepts using sub-wavelength features. By taking advantage of this, we demonstrate a cost-effective robust single-etch sub-wavelength structure based fiber-chip coupler with a coupling efficiency of 40 % and high

  14. Episodes of the Klaipeda/Memel Anschluss in March, 1939

    OpenAIRE

    Arbušauskaitė Arūnė

    2012-01-01

    This article discusses the complicated diplomatic relations between Lithuania and Germany in 1938—1939 on the basis of archive documents and historical studies. The author identifies the methods used by the Germans in the Klaipėda region in order to destroy the system established by the Treaty of Versailles, propagate national socialist ideas among the population, and spread a positive attitude to the restoration of the region as a part of the German Reich. The author offers a detailed analys...

  15. Collateral damage-free debridement using 193nm ArF laser

    Science.gov (United States)

    Wynne, James J.; Felsenstein, Jerome M.; Trzcinski, Robert; Zupanski-Nielsen, Donna; Connors, Daniel P.

    2011-03-01

    Burn eschar and other necrotic areas of the skin and soft tissue are anhydrous compared to the underlying viable tissue. A 193 nm ArF excimer laser, emitting electromagnetic radiation at 6.4 eV at fluence exceeding the ablation threshold, will debride such necrotic areas. Because such radiation is strongly absorbed by aqueous chloride ions through the nonthermal process of electron photodetachment, debridement will cease when hydrated (with chloride ions) viable tissue is exposed, avoiding collateral damage to this tissue. Such tissue will be sterile and ready for further treatment, such as a wound dressing and/or a skin graft.

  16. 193 nm deep-ultraviolet solar-blind cubic boron nitride based photodetectors

    Science.gov (United States)

    Soltani, A.; Barkad, H. A.; Mattalah, M.; Benbakhti, B.; De Jaeger, J.-C.; Chong, Y. M.; Zou, Y. S.; Zhang, W. J.; Lee, S. T.; BenMoussa, A.; Giordanengo, B.; Hochedez, J.-F.

    2008-02-01

    Deep-ultraviolet (DUV) solar-blind photodetectors based on high-quality cubic boron nitride (cBN) films with a metal/semiconductor/metal configuration were fabricated. The design of interdigitated circular electrodes enables high homogeneity of electric field between pads. The DUV photodetectors present a peak responsivity at 180nm with a very sharp cutoff wavelength at 193nm and a visible rejection ratio (180 versus 250nm) of more than four orders of magnitude. The characteristics of the photodetectors present extremely low dark current, high breakdown voltage, and high responsivity, suggesting that cBN films are very promising for DUV sensing.

  17. A triple nucleus in the Brightest Cluster Galaxy in Abell 193

    CERN Document Server

    Seigar, M S; Chorney, N E; Seigar, Marc S.; Lynam, Paul D.; Chorney, Nicole E.

    2003-01-01

    We present a ground-based near-infrared K-band image and an HST/WFPC2 image of the brightest cluster galaxy in Abell 193 (IC 1695). This object was selected as the central cluster galaxy using X-ray information. Both images reveal a triple nucleus structure. Previously, this galaxy was thought to have only 2 nuclei. We present colours and magnitudes and a colour plot of the three nuclei. The nuclear structure and colours of the nuclei in this galaxy suggest that a merger may have taken place in its recent history.

  18. Measurement of initial absorption of fused silica at 193nm using laser induced deflection technique (LID)

    Science.gov (United States)

    Schönfeld, Dörte; Klett, Ursula; Mühlig, Christian; Thomas, Stephan

    2008-01-01

    The ongoing development in microlithography towards further miniaturization of structures creates a strong demand for lens material with nearly ideal optical properties. Beside the highly demanding requirements on homogeneity and stress induced birefringence (SIB), low absorption is a key factor. Even a small absorption is associated with a temperature increase and results in thermally induced local variations of refractive index and SIB. This could affect the achievable resolution of the lithographic process. The total absorption of the material is composed of initial absorption and of absorption induced during irradiation. Thus, the optimization of both improves the lifetime of the material. In principal, it is possible to measure transmission and scattering with a suitable spectrometer assembly and calculate absorption from them. However, owing to the influence of sample surfaces and errors of measurement, these methods usually do not provide satisfactory results for highly light-transmissive fused silica. Therefore, it is most desirable to find a technique that is capable of directly measuring absorption coefficients in the range of (1...10)•10 -4 cm -1 (base 10) directly. We report our first results for fused silica achieved with the LID technique. Besides a fused silica grade designed for 193 nm applications, grades with higher absorption at 193 nm were measured to test the LID technique. A special focus was set on the possibility of measuring initial absorption without the influence of degradation effects.

  19. Comparison of 193 nm and 308 nm laser liquid printing by shadowgraphy imaging

    Science.gov (United States)

    Palla-Papavlu, A.; Shaw-Stewart, J.; Mattle, T.; Dinca, V.; Lippert, T.; Wokaun, A.; Dinescu, M.

    2013-08-01

    Over the last years laser-induced forward transfer has emerged as a versatile and powerful tool for engineering surfaces with active compounds. Soft, easily damageable materials can be transferred using a triazene polymer as a sacrificial layer which acts as a pressure generator and at the same time protects the material from direct laser irradiation. To understand and optimize the transfer process of biomolecules in liquid solution by using an intermediate triazene polymer photosensitive layer, shadowgraphy imaging is carried out. Two laser systems i.e. an ArF laser operating at 193 nm and a XeCl laser operating at 308 nm are applied for the transfer. Solutions with 50% v/v glycerol concentration are prepared and the influence of the triazene polymer sacrificial layer thickness (60 nm) on the deposits is studied. The shadowgraphy images reveal a pronounced difference between laser-induced forward transfer using 193 nm or 308 nm, i.e. very different shapes of the ejected liquid.

  20. Study of the inner Bremsstrahlung following the electron-capture decay of {sup 193} Pt

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, J.Y.Z.; Cruz, M.T.F. da; Martins, M.N.; Santos, R.T. dos [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Zamboni, C.B.; Hamada, M.M.; Camargo, S.P. de; Medeiros, J.A.G. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil); Hindi, M.M. [Tennessee Technological Univ., Cookeville, TN (United States). Dept. of Physics

    1997-12-31

    We are measuring the inner Bremsstrahlung (I B) photons emitted in some of the electron-capture decays of {sup 193} Pt. The source was prepared with highly pure metal Pt. It was irradiated with neutron for 52 days and let to cool down for eight months. The remaining activities were due to {sup 193} Pt{sup g} (half-life 50 yr) and {sup 192} Ir (half-life 74 d), the latter coming from (n, {gamma}) reactions on a small content of Ir. We have used a radiochemistry method to reduce the Ir content of the source. The resulting Pt compound will be dissolved in a plastic scintillator disk. Most of the {sup 192} Ir decays are {beta}{sup -} and their signal in the plastic will be used as a veto for the I B-photon detector. We have performed simulations of the efficiency and absorption effects in the detection geometry. (author) 6 refs., 1 fig.; juan at if.usp.br; czamboni at net.ipen.br; hindi at hindi.physics.tntech.edu

  1. An AC phase measuring interferometer for measuring dn/dT of fused silica and calcium fluoride at 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Shagam, R.N.

    1998-09-01

    A novel method for the measurement of the change in index of refraction vs. temperature (dn/dT) of fused silica and calcium fluoride at the 193 nm wavelength has been developed in support of thermal modeling efforts for the development of 193 nm-based photolithographic exposure tools. The method, based upon grating lateral shear interferometry, uses a transmissive linear grating to divide a 193 nm laser beam into several beam paths by diffraction which propagate through separate identical material samples. One diffracted order passing through one sample overlaps the undiffracted beam from a second sample and forms interference fringes dependent upon the optical path difference between the two samples. Optical phase delay due to an index change from heating one of the samples causes the interference fringes to change sinusoidally with phase. The interferometer also makes use of AC phase measurement techniques through lateral translation of the grating. Results for several samples of fused silica and calcium fluoride are demonstrated.

  2. A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells.

    Directory of Open Access Journals (Sweden)

    Frank H C Cheng

    Full Text Available Accumulating data indicate that cancer stem cells contribute to tumor chemoresistance and their persistence alters clinical outcome. Our previous study has shown that ovarian cancer may be initiated by ovarian cancer initiating cells (OCIC characterized by surface antigen CD44 and c-KIT (CD117. It has been experimentally demonstrated that a microRNA, namely miR-193a, targets c-KIT mRNA for degradation and could play a crucial role in ovarian cancer development. How miR-193a is regulated is poorly understood and the emerging picture is complex. To unravel this complexity, we propose a mathematical model to explore how estrogen-mediated up-regulation of another target of miR-193a, namely E2F6, can attenuate the function of miR-193a in two ways, one through a competition of E2F6 and c-KIT transcripts for miR-193a, and second by binding of E2F6 protein, in association with a polycomb complex, to the promoter of miR-193a to down-regulate its transcription. Our model predicts that this bimodal control increases the expression of c-KIT and that the second mode of epigenetic regulation is required to generate a switching behavior in c-KIT and E2F6 expressions. Additional analysis of the TCGA ovarian cancer dataset demonstrates that ovarian cancer patients with low expression of EZH2, a polycomb-group family protein, show positive correlation between E2F6 and c-KIT. We conjecture that a simultaneous EZH2 inhibition and anti-estrogen therapy can constitute an effective combined therapeutic strategy against ovarian cancer.

  3. Photodissociation of HCl at 193.3 nm: Spin{endash}orbit branching ratio

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J.; Dulligan, M.; Wittig, C. [Department of Chemistry, University of Southern California, Los Angeles, California 90089-0482 (United States)

    1997-08-01

    HCl was photodissociated by ultraviolet (uv) radiation at 193.3 nm. Time-of-flight spectra of the hydrogen atom fragment provided the spin{endash}orbit state distribution of the chlorine fragment, [Cl({sup 2}P{sub 1/2})]/[Cl({sup 2}P{sub 3/2})]=0.69{plus_minus}0.02, in excellent agreement with recent theoretical studies. The H atom angular distribution studied by changing the uv photolysis laser polarization confirmed a dominant A{sup 1}{Pi}{l_arrow}X{sup 1}{Sigma}{sup +} electronic transition in the photoexcitation process ({beta}={minus}1.01{plus_minus}0.04 and {beta}{sup {asterisk}}={minus}0.94{plus_minus}0.07). {copyright} {ital 1997 American Institute of Physics.}

  4. Research development of thermal aberration in 193nm lithography exposure system

    Science.gov (United States)

    Wang, Yueqiang; Liu, Yong

    2014-08-01

    Lithographic exposure is the key process in the manufacture of the integrated circuit, and the performance of exposure system decides the level of microelectronic manufacture technology. Nowadays, the 193nm ArF immersion exposure tool is widely used by the IC manufacturer. With the uniformity of critical dimension (CDU) and overlay become tighter and the requirement for throughput become higher, the thermal aberration caused by lens material and structure absorbing the laser energy cannot be neglected. In this paper, we introduce the efforts and methods that researcher on thermal aberration and its control. Further, these methods were compared to show their own pros and cons. Finally we investigated the challenges of thermal aberration control for state of the art technologies.

  5. Plasma channel formed by ultraviolet laser pulses at 193 nm in air

    Institute of Scientific and Technical Information of China (English)

    Yuanyuan Ma; Xin Lu; Tingting Xi; Qihuang Gong; Jie Zhang

    2009-01-01

    The propagation of picosecond deep ultraviolet laser pulse at wavelength of 193 nm in air is numerically investigated.Long plasma channel can be formed due to the competition between Kerr self-focusing and ionization induced defocusing.The plasma channel with electron density of above 1013/cma can be formed over 70 m by 50-ps,20-mJ laser pulses.The fluctuation of laser intensity and electron density inside ultraviolet(UV)plasma channel is significantly lower than that of infrared pulse.The linear absorption of UV laser by air is considered in the simulation and it is shown that the linear absorption is important for the limit of the length of plasma channel.

  6. Morphological Studies of the PWN Candidate HESS J1809-193

    CERN Document Server

    Komin, Nu; Djannati-Ataï, A; Gallant, Y A; Kosack, K; Pühlhofer, G; Schwemmer, S

    2007-01-01

    The source HESS J1809-193 was discovered in 2006 in data of the Galactic Plane survey, followed by several re-observations. It shows a hard gamma-ray spectrum and the emission is clearly extended. Its vicinity to PSR J1809-1917, a high spin-down luminosity pulsar powerful enough to drive the observed gamma-ray emission, makes it a plausible candidate for a TeV Pulsar Wind Nebula (PWN). On the other hand, in this region of the sky a number of faint, radio-emitting supernova remnants can be found, making a firm conclusion on the source type difficult. Here we present a detailed morphological study of recent H.E.S.S. data and compare the result with X-ray measurements taken with Chandra and radio data. The association with a PWN is likely, but contributions from supernova remnants cannot be ruled out.

  7. Corneal stromal wound healing in rabbits after 193-nm excimer laser surface ablation.

    Science.gov (United States)

    Hanna, K D; Pouliquen, Y; Waring, G O; Savoldelli, M; Cotter, J; Morton, K; Menasche, M

    1989-06-01

    An argon fluoride excimer laser (193 nm) with a moving slit delivery system was used to perform anterior myopic keratomileusis in both eyes of 24 New Zealand white rabbits. Rabbits were killed immediately after ablation and at intervals up to 100 days. By slit-lamp microscopy, four rabbits at day 100 exhibited four clear corneas and four corneas had central, spotty, subepithelial haze. Light and electron microscopy documented corneal healing. In the early stages a transient acellular zone in the anterior stroma appeared over a period of three weeks, followed by an increased number of fibrocytes. In the corneas with opacification, focal areas of 20-microns-thick subepithelial scarring were present. An unexpected finding was transient damage to posterior stromal keratocytes and endothelial cells. The endothelium produced a layer of granular material that migrated anteriorly across Descemet's membrane. Immunochemistry at day 6 showed a marked staining for collagen IV, proteoglycans, fibronectin, and laminin.

  8. 193 nm Excimer laser processing of Si/Ge/Si(100) micropatterns

    Science.gov (United States)

    Gontad, F.; Conde, J. C.; Chiussi, S.; Serra, C.; González, P.

    2016-01-01

    193 nm Excimer laser assisted growth and crystallization of amorphous Si/Ge bilayer patterns with circular structures of 3 μm diameter and around 25 nm total thickness, is presented. Amorphous patterns were grown by Laser induced Chemical Vapor Deposition, using nanostencils as shadow masks and then irradiated with the same laser to induce structural and compositional modifications for producing crystalline SiGe alloys through fast melting/solidification cycles. Compositional and structural analyses demonstrated that pulses of 240 mJ/cm2 lead to graded SiGe alloys with Si rich discs of 2 μm diameter on top, a buried Ge layer, and Ge rich SiGe rings surrounding each feature, as predicted by previous numerical simulation.

  9. Inspection of advanced computational lithography logic reticles using a 193-nm inspection system

    Science.gov (United States)

    Yu, Ching-Fang; Lin, Mei-Chun; Lai, Mei-Tsu; Hsu, Luke T. H.; Chin, Angus; Lee, S. C.; Yen, Anthony; Wang, Jim; Chen, Ellison; Wu, David; Broadbent, William H.; Huang, William; Zhu, Zinggang

    2010-09-01

    We report inspection results of early 22-nm logic reticles designed with both conventional and computational lithography methods. Inspection is performed using a state-of-the-art 193-nm reticle inspection system in the reticleplane inspection mode (RPI) where both rule-based sensitivity control (RSC) and a newer modelbased sensitivity control (MSC) method are tested. The evaluation includes defect detection performance using several special test reticles designed with both conventional and computational lithography methods; the reticles contain a variety of programmed critical defects which are measured based on wafer print impact. Also included are inspection results from several full-field product reticles designed with both conventional and computational lithography methods to determine if low nuisance-defect counts can be achieved. These early reticles are largely single-die and all inspections are performed in the die-to-database inspection mode only.

  10. Photolysis of ketene at 193 nm and the rate constant for H + HCCO at 297 K.

    Energy Technology Data Exchange (ETDEWEB)

    Glass, G. P.; Kumaran, S. S.; Michael, J. V.; Chemistry

    2000-01-01

    The 193 nm photolysis of ketene was studied by measuring the amount of atomic hydrogen produced when very dilute ketene/Ar and ketene/H{sub 2} mixtures were irradiated by a single pulse from an ArF excimer laser. Absolute concentrations of atomic hydrogen were monitored over a time interval of 0-2.5 ms by using Lyman-{alpha} atomic resonance absorption spectroscopy (ARAS). Four different photodissociation channels of ketene were identified: H{sub 2}CCO + hv gives (a) CH{sub 2}({sup 3}B1) + CO; (b) CH{sub 2}({sup 1}A{sub 1}) + CO; (c) HCCO + H; and (d) C{sub 2}O(b{sup -1}{Sigma}{sup +}) + H{sub 2}. The quantum yields for each channel were measured as {phi}{sub a} = 0.628, {phi}{sub b} = 0.193, {phi}{sub 3}= 0.107, and {phi}{sub d} = 0.072, respectively. To explore the secondary chemistry that occurred when using higher pressure H{sub 2}CCO/Ar mixtures, a mechanism was constructed that used well-documented reactions and, for most processes, rate constants that had already been accurately determined. Modeling studies using this mechanism showed the [H] profile to be determined largely by the rate of the reaction H + HCCO {yields} CH{sub 2} + CO. An excellent fit to all of the experimental data was obtained when k{sub 2} = (1.7 {+-} 0.3) x 10{sup -10} cm{sup 3} molecule{sup -1} s{sup -1}.

  11. Three-body dissociations: The photodissociation of dimethyl sulfoxide at 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Blank, D.A.; North, S.W.; Stranges, D. [Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    When a molecule with two equivalent chemical bonds is excited above the threshold for dissociation of both bonds, how the rupture of the two bonds is temporally coupled becomes a salient question. Following absorption at 193 nm dimethyl sulfoxide (CH{sub 3}SOCH{sub 3}) contains enough energy to rupture both C-S bonds. This can happen in a stepwise (reaction 1) or concerted (reaction 2) fashion where the authors use rotation of the SOCH{sub 3} intermediate prior to dissociation to define a stepwise dissociation: (1) CH{sub 3}SOCH{sub 3} {r_arrow} 2CH{sub 3} + SO; (2a) CH{sub 3}SOCH{sub 3} {r_arrow} CH{sub 3} + SOCH{sub 3}; and (2b) SOCH{sub 3} {r_arrow} SO + CH{sub 3}. Recently, the dissociation of dimethyl sulfoxide following absorption at 193 nm was suggested to involve simultaneous cleavage of both C-S bonds on an excited electronic surface. This conclusion was inferred from laser induced fluorescence (LIF) and resonant multiphoton ionization (2+1 REMPI) measurements of the internal energy content in the CH{sub 3} and SO photoproducts and a near unity quantum yield measured for SO. Since this type of concerted three body dissociation is very interesting and a rather rare event in photodissociation dynamics, the authors chose to investigate this system using the technique of photofragment translational spectroscopy at beamline 9.0.2.1. The soft photoionization provided by the VUV undulator radiation allowed the authors to probe the SOCH{sub 3} intermediate which had not been previously observed and provided good evidence that the dissociation of dimethyl sulfoxide primarily proceeds via a two step dissociation, reaction 2.

  12. Photoinitiated decomposition of substituted ethylenes: The photodissociation of vinyl chloride and acrylonitrile at 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Blank, D.A.; Suits, A.G.; Lee, Y.T. [Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    Ethylene and its substituted analogues (H{sub 2}CCHX) are important molecules in hydrogen combustion. As the simplest {pi}-bonded hydrocarbons these molecules serve as prototypical systems for understanding the decomposition of this important class of compounds. The authors have used the technique of photofragment translational spectroscopy at beamline 9.0.2.1 to investigate the dissociation of vinyl chloride (X=Cl) and acrylonitrile (X=CN) following absorption at 193 nm. The technique uses a molecular beam of the reactant seeded in helium which is crossed at 90 degrees with the output of an excimer laser operating on the ArF transition, 193.3 nm. The neutral photoproducts which recoil out of the molecular beam travel 15.1 cm where they are photoionized by the VUV undulator radiation, mass selected, and counted as a function of time. The molecular beam source is rotatable about the axis of the dissociation laser. The authors have directly observed all four of the following dissociation channels for both systems: (1) H{sub 2}CCHX {r_arrow} H + C{sub 2}H{sub 2}X; (2) H{sub 2}CCHX {r_arrow} X + C{sub 2}H{sub 3}; (3) H{sub 2}CCHX {r_arrow} H{sub 2} + C{sub 2}HX; and (4) H{sub 2}CCHX {r_arrow} HX + C{sub 2}H{sub 2}. They measured translational energy distributions for all of the observed channels and measured the photoionization onset for many of the photoproducts which provided information about their chemical identity and internal energy content. In the case of acrylonitrile, selective product photoionization provided the ability to discriminate between channels 2 and 4 which result in the same product mass combination.

  13. Decolorization of 1:2 metal complex dye Acid blue 193 by a newly isolated fungus, Cladosporium cladosporioides

    Energy Technology Data Exchange (ETDEWEB)

    Vijaykumar, M.H.; Veeranagouda, Y.; Neelakanteshwar, K.; Karegoudar, T.B. [Gulbarga University, Gulbarga (India). Dept. of Biochemistry

    2006-02-15

    A fungus Cladosporium cladosporioides isolated from coal sample as a decolorizing microorganism. It decolorized five different azo and triphenylmethane dyes like acid blue 193, acid black 210, crystal violet, reactive black B(S) and reactive black BL/LPR both on solid and in liquid broth medium. Culture broth of this fungus decolorized completely 100 mg of acid blue 193 l{sup -1} in 8 days. The extracellular enzyme of Cladosporium cladosporioides decolorized acid blue 193 on repeated addition to a total (out of 700 mg l{sup -1}) concentration of 564 mg l{sup -1} within 168 h without significant decline in the activity, showing the resistant property of Cladosporium cladosporioides to a high concentration of the dye. The optimal temperature 40{sup o}C, pH 5.6 and sugar concentration of 4% required for decolorization of acid blue 193. Cladosporium cladosporioides showed manganese peroxidase activity with 41 U l{sup -1}, laccase activity with 1413 U l{sup -1} and lignin peroxidase activity was negligible after day 8 of incubation.

  14. Expression of a transgene encoding mutant p193/CUL7 preserves cardiac function and limits infarct expansion after myocardial infarction

    NARCIS (Netherlands)

    Hassink, R. J.; Nakajima, H.; Nakajima, H. O.; Doevendans, P. A.; Field, L. J.

    2009-01-01

    Background: Transgenic mice expressing the dominant interfering p193 protein in cardiomyocytes (MHC-1152stop mice) exhibit an induction of cell cycle activity and altered remodelling after experimental myocardial infarction (MI). Objective: To determine whether the altered remodelling results in imp

  15. 76 FR 30956 - Outer Continental Shelf, Alaska OCS Region, Chukchi Sea Planning Area, Oil and Gas Lease Sale 193

    Science.gov (United States)

    2011-05-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management, Regulation and Enforcement Outer Continental Shelf, Alaska OCS Region, Chukchi Sea Planning Area, Oil and Gas Lease Sale 193 AGENCY: Bureau of Ocean Energy...

  16. Determination of effective resonance energy for the 193Ir(n,γ)194Ir reaction by the cadmium ratio method

    Science.gov (United States)

    Budak, Mustafa Guray; Karadag, Mustafa; Yücel, Haluk

    2016-04-01

    In this work, the effective resonance energy, Ebarr -value for the 193Ir(n,γ)194Ir reaction was measured using cadmium ratio method. A dual monitor (197Au-98Mo), which has convenient resonance properties, was employed for characterization of the irradiation sites. Then analytical grade iridium oxide samples diluted with CaCO3 to lower neutron self-shielding effect stacked in small cylindrical Teflon boxes were irradiated once with a 1 mm thick Cd cylindrical box placed in a thermalized neutron field of an 241Am-Be neutron source then without it. The activities produced in samples during 193Ir(n,γ)194Ir reaction were measured using a p-type HPGe detector γ-ray spectrometer with a 44.8% relative efficiency. The correction factors for thermal, epithermal neutron self-shielding (Gth, Gepi), true coincidence summing (Fcoi) and gamma-ray self-absorption (Fs) effects were determined with appropriate approaches and programs. Thus, the experimental Ebarr -value was determined to be 2.65 ± 0.61 eV for 193Ir target nuclide. The recent data for Q0 and FCd values for Ebarr determination were based on k0-NAA online database. The present experimental Ebarr value was calculated and compared with more recent values for Q0 and FCd for 193Ir. Additionally, the Ebarr -values was theoretically calculated from the up-to-date resonance data obtained from ENDF/B VII library using two different approaches. Since there is no experimentally determined Ebarr -value for the 193Ir isotope, the results are compared with the calculated ones given in the literature.

  17. a193yb.m77t and a193yb.h77t: MGD77T data and header files for single-beam bathymetry data for field activity A-1-93-YB in Yakukat Bay, Alaska from 08/21/1993 to 08/27/1993

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with GPS navigation data was collected as part of the U.S. Geological Survey cruise A-1-93-YB. The cruise was conducted in Yakukat...

  18. k193hw.m77t and k193hw.h77t: MGD77T data and header files for single-beam bathymetry data for field activity K-1-93-HW in Oahu, Hawaii from 02/20/1993 to 02/26/1993

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with DGPS navigation data was collected as part of the U.S. Geological Survey cruise K-1-93-HW. The cruise was conducted in Oahu,...

  19. PH2 internal energy distribution produced by the 193 nm photodissociation of PH3

    Science.gov (United States)

    Baugh, D.; Koplitz, B.; Xu, Z.; Wittig, C.

    1988-01-01

    Experimental results involving 193 nm PH3 photodissociation are reported. Detection of the PH2 fragment using laser induced fluorescence suggests that PH2 is formed with appreciable internal excitation, but no quantitative results concerning nascent PH2 could be obtained using this direct method. In related kinetics studies, the reaction of thermalized (300 K) PH2 with O2 yields a rate coefficient of 2.7×10-13 cm3 molecule-1 s-1, while PH2+NO is rather unreactive (k<10-14 cm3 molecule-1 s-1). In separate experiments, sub-Doppler spectroscopy on the H-atom fragment at Lyman-α (121.6 nm) allowed the center-of-mass kinetic energy distribution to be extracted; the PH2 internal energy distribution was obtained using energy conservation. Most of the available energy (E° ≂hν-D0=22 000 cm-1) appears as PH2 internal excitation; the mean internal energy is 14 000 cm-1 and the distribution peaks at ˜19 000 cm-1. The experimental distribution compares favorably with a simple statistical (prior) calculation, and the agreement is discussed in terms of possible photodissociation mechanisms.

  20. Photolysis of pure solid O3 and O2 films at 193 nm

    CERN Document Server

    Raut, U; Famá, M; Baragiola, R A

    2010-01-01

    We studied quantitatively the photochemistry of solid O3 and O2 films at 193 nm and 22 K with infrared spectroscopy and microgravimetry. Photolysis of pure ozone destroyed O3, but a small amount of ozone remained in the film at high fluence. Photolysis of pure O2 produced O3 in an amount that increased with photon fluence to a stationary level. For both O2 and O3 films, the O3:O2 ratio at saturation is 0.03, nearly 10-30 times larger than those obtained in gas phase photolysis. This enhancement is attributed to the increased photodissociation of O2 due to photoabsorption by O2 dimers, a process significant at solid state densities. We obtain initial quantum yield for ozone synthesis from solid oxygen, {\\Phi} (O3) = 0.18 and for destruction of ozone and oxygen in their parent solids, {\\Phi} (- O3) = 1.7 and {\\Phi} (-O2) = 0.28. Combined with known photoabsorption cross sections, we estimate probabilities for germinate recombination of 0.15 for O3 fragments and 0.90 for oxygen atoms from O2 dissociation. Using ...

  1. Understanding dissolution behavior of 193nm photoresists in organic solvent developers

    Science.gov (United States)

    Lee, Seung-Hyun; Park, Jong Keun; Cardolaccia, Thomas; Sun, Jibin; Andes, Cecily; O'Connell, Kathleen; Barclay, George G.

    2012-03-01

    Herein, we investigate the dissolution behavior of 193-nm chemically amplified resist in different organic solvents at a mechanistic level. We previously reported the effect of solvent developers on the negative tone development (NTD) process in both dry and immersion lithography, and demonstrated various resist performance parameters such as photospeed, critical dimension uniformity, and dissolution rate contrast are strongly affected by chemical nature of the organic developer. We further pursued the investigation by examining the dependence of resist dissolution behavior on their solubility properties using Hansen Solubility Parameter (HSP). The effects of monomer structure, and resist composition, and the effects of different developer chemistry on dissolution behaviors were evaluated by using laser interferometry and quartz crystal microbalance. We have found that dissolution behaviors of methacrylate based resists are significantly different in different organic solvent developers such as OSDTM-1000 Developer* and n-butyl acetate (nBA), affecting their resist performance. This study reveals that understanding the resist dissolution behavior helps to design robust NTD materials for higher resolution imaging.

  2. Minimizing wafer defectivity during high-temperature baking of organic films in 193nm lithography

    Science.gov (United States)

    Randall, Mai; Longstaff, Christopher; Ueda, Kenichi; Nicholson, Jim; Winter, Thomas

    2006-03-01

    Demands for continued defect reduction in 300mm IC manufacturing is driving process engineers to examine all aspects of the apply process for improvement. Process engineers, and their respective tool sets, are required to process films at temperatures above the boiling point of the casting solvents. This can potentially lead to the sublimation of the film chemical components. The current methods used to minimize wafer defectivity due to bake residues include frequent cleaning of bake plate modules and surrounding equipment, process optimization, and hardware improvements until more robust chemistries are available. IBM has evaluated the Tokyo Electron CLEAN TRACK TM ACT TM 12 high exhaust high temperature hotplate (HHP) lid to minimize wafer level contamination due to the outgasing of a bottom anti-reflective coating (BARC) films during the high temperature bake process. Goal was to minimize airborne contamination (particles in free space), reduce hotplate contamination build up, and ultimately reduce defects on the wafer. This evaluation was performed on a 193nm BARC material. Evaluation data included visual hardware inspections, airborne particle counting, relative thickness build up measurements on hotplate lids, wafer level defect measurements, and electrical open fail rate. Film coat thickness mean and uniformity were also checked to compare the high exhaust HHP with the standard HHP lid. Chemical analysis of the HHP module residue was performed to identify the source material. The work will quantify potential cost savings achieved by reducing added wafer defects during processing and extending PM frequency for equipment cleaning.

  3. 193-nm radiation durability study of MoSi binary mask and resulting lithographic performance

    Science.gov (United States)

    Servin, Isabelle; Belledent, Jérôme; Pain, Laurent; Connolly, Brid; Sczyrba, Martin; Lamantia, Matt

    2011-05-01

    Dimensions on mask continue to shrink to keep up with the ITRS roadmap. This has implications on the material of choice for the blanks. For example, the new binary OMOG stack (Opaque MOSi on Glass) was successfully introduced to meet the mask specifications at the 32nm technology node. Obviously 193-nm optical lithography will be further used in production at even higher NA and lower k1 emphasizing, for example, the impact on wafer of any electromagnetic field migration effects. Indeed, long term radiation damage inducing CD growth and consequently, device yield loss, has already been reported [1, 2]. This mechanism, known as Electric Field induced Migration of chrome (EMF) often shortens the mask's lifetime. Here, a study was conducted to investigate the impact of intensive ArF scanner exposure both on final wafer and mask performances. The Si printed wafers measured with top-down CD-SEM were characterized with respect to CD uniformity, linearity, Sub Resolution Assist Feature (SRAF) printability through process window, MEEF, DOF, and OPC accuracy. The data was also correlated to advanced mask inspection results (e.g. AIMSTM) taken at the same location. More precisely, this work follows a preliminary study [1] which pointed out that OMOG is less sensitive to radiation than standard COG (Chrome On Glass). And, in this paper, we report on results obtained at higher energy to determine the ultimate lifetime of OMOG masks.

  4. A new look at the photodissociation of methyl iodide at 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Hong; Pratt, S. T. [Argonne National Laboratory, Argonne, Illinois 60439 (United States)

    2013-12-07

    A new measurement of the photodissociation of CH{sub 3}I at 193 nm is reported in which we use a combination of vacuum ultraviolet photoionization and velocity map ion imaging. The iodine photofragments are probed by single-photon ionization at photon energies above and below the photoionization threshold of I({sup 2}P{sub 3/2}). The relative I({sup 2}P{sub 3/2}) and I{sup *}({sup 2}P{sub 1/2}) photoionization cross sections are determined at these wavelengths by using the known branching fractions for the photodissociation at 266 nm. Velocity map ion images indicate that the branching fraction for I({sup 2}P{sub 3/2}) atoms is non-zero, and yield a value of 0.07 ± 0.01. Interestingly, the translational energy distribution extracted from the image shows that the translational energy of the I({sup 2}P{sub 3/2}) fragments is significantly smaller than that of the I{sup *}({sup 2}P{sub 1/2}) atoms. This observation indicates the internal rotational/vibrational energy of the CH{sub 3} co-fragment is very high in the I({sup 2}P{sub 3/2}) channel. The results can be interpreted in a manner consistent with the previous measurements, and provide a more complete picture of the dissociation dynamics of this prototypical molecule.

  5. Photodissociation of the Propargyl (C3D3) Radicals at 248 nm and 193 nm

    Energy Technology Data Exchange (ETDEWEB)

    Neumark., D.M.; Crider, P.E.; Castiglioni, L.; Kautzman, K.K.

    2009-01-21

    The photodissociation of perdeuterated propargyl (D{sub 2}CCCD) and propynyl (D{sub 3}CCC) radicals was investigated using fast beam photofragment translational spectroscopy. Radicals were produced from their respective anions by photodetachment at 540 nm and 450 nm (below and above the electron affinity of propynyl). The radicals were then photodissociated by 248 nm or 193 nm light. The recoiling photofragments were detected in coincidence with a time- and position-sensitive detector. Three channels were observed: D{sub 2} loss, CD + C{sub 2}D{sub 2}, and CD{sub 3} + C{sub 2}. Obervation of the D loss channel was incompatible with this experiment and was not attempted. Our translational energy distributions for D{sub 2} loss peaked at nonzero translational energy, consistent with ground state dissociation over small (< 1 eV) exit barriers with respect to separated products. Translational energy distributions for the two heavy channels peaked near zero kinetic energy, indicating dissociation on the ground state in the absence of exit barriers.

  6. Product study of the photolysis of ketene and ethyl ethynyl ether at 193.3 nm.

    Science.gov (United States)

    Fockenberg, Christopher

    2005-08-18

    The product distributions of the excimer laser photolysis of ketene (CH2CO) and ethyl ethynyl ether (C2H5OCCH) at lambda = 193.3 nm (ArF) were studied using a time-of-flight mass spectrometer (TOFMS) as an analytical tool. Ketene was photolyzed in bath gases consisting of mixtures of He and H2/D2 at various mixing ratios at constant total pressures of 4 Torr and temperature of about 300 K. Singlet methylene (1CH2) produced in the photolysis of ketene was almost instantaneously converted either to triplet methylene (3CH2) or to methyl radicals in collisions with He and H2 or D2. By extrapolating the methyl and methylene signals to zero time after photolysis, initial concentrations of these radicals were obtained. Analyzing the initial 3CH2 and CH3 concentrations as functions of hydrogen-to-helium ratios as well as simulating the observed traces of reactant and product species resulted in 1CH2 + CO (66 +/- 8)%, as the main product channel of the ketene photolysis with smaller contributions from HCCO + H (17 +/- 7)% and 3CH2 + CO (6 +/- 9)%. Hydrogen atoms, acetylene, ethylene, ethyl, and ketenyl radicals, and small amounts of ketene were observed as primary products of the ethyl ethynyl ether photolysis. Quantification of C2H2, C2H4, C2H5, and CH2CO product leads to a HCCO yield of (91 +/- 14)%.

  7. Generation of intense 10-ps, 193-nm pulses using simple distributed feedback dye lasers and an ArF(*) amplifier.

    Science.gov (United States)

    Hatten, D L; Cui, Y; Iii, W T; Mikes, T; Goldhar, J

    1992-11-20

    A pair of holographic distributed feedback dye lasers is used to generate 10-ps pulses at two selected wavelengths that are mixed in a BBO crystal to produce a pulse ~ 10 ps in duration at 193 nm. This seed pulse is subsequently amplified in an ArF(*) excimer laser to an energy of 10-15 mJ with <40 microJ in amplified spontaneous emission. The pulses are nearly transform limited and diffraction limited.

  8. Preparation of Rh[16aneS4-diol](211)At and Ir[16aneS4-diol](211)At complexes as potential precursors for astatine radiopharmaceuticals. Part I: Synthesis.

    Science.gov (United States)

    Pruszyński, Marek; Bilewicz, Aleksander; Zalutsky, Michael R

    2008-04-01

    The goal of this study was to evaluate a new approach that can be applied for labeling biomolecules with (211)At. Many astatine compounds that have been synthesized are unstable in vivo, providing motivation for seeking different (211)At labeling strategies. The approach evaluated in this study was to attach astatide anions to soft metal cations, which are also complexed by a bifunctional ligand. Ultimately, this complex could in principle be subsequently conjugated to a biomolecule with the proper selection of ligand functionality. We report here the attachment of (211)At(-) and *I(-) (*I = (131)I or (125)I) anions to the soft metal cations Rh(III) and Ir(III), which are complexed by the 1,5,9,13-tetrathiacyclohexadecane-3,11-diol (16aneS4-diol) ligand. Radioactive *I(-) anions were used for preliminary studies directed at the optimization of reaction conditions and to provide a baseline for comparison of results with (211)At. Four complexes Rh[16aneS4-diol]*I/(211)At and Ir[16aneS4-diol]*I/(211)At were synthesized in high yield in a one-step procedure, and the products were characterized mainly by paper electrophoresis and reversed-phase HPLC. The influences of time and temperature of heating and concentrations of metal cations and sulfur ligand 16aneS4-diol, as well as pH on the reaction yields were determined. Yields of about 80% were obtained when the quantities of Rh(III) or Ir(III) cations and 16aneS4-diol ligand in the solutions were 62.5 nmol and 250 nmol, respectively, and the pH ranged 3.0-4.0. Syntheses required heating for 1-1.5 h at 75-80 degrees C. The influence of microwave heating on the time and completeness of the complexation reaction was evaluated and compared with the conventional method of heating in an oil bath. Microwave synthesis accelerates reactions significantly. With microwave heating, yields of about 75% for Rh[16aneS4-diol](131)I and Ir[16aneS4-diol](131)I complexes were obtained after only 20 min exposure of the reaction mixtures to

  9. Photodissociation of methanol at 193.3 nm: Translational energy release spectra

    Science.gov (United States)

    Wen, Y.; Segall, J.; Dulligan, M.; Wittig, C.

    1994-10-01

    Center-of-mass translational energy distributions of the dominant primary products resulting from 193.3 nm excitation of jet-cooled CH3OH, CH3OD, and CD3OH were obtained by using the high-n Rydberg time-of-flight (HRTOF) technique. The appearance threshold in the HRTOF spectrum yields a bond dissociation energy, D0(CH3O-H), of 105±1 kcal mol-1, in agreement with recent literature values. Translational energy release spectra from the three isotopomers exhibit progressions of 950±100 cm-1, which are attributed to excitation in the ν3 O-CH3 stretch of the methoxy product. The progressions peak at v=1, with population out to at least v=5. This differs from the results of a recent wave packet dynamics study on a calculated excited state potential energy surface [Marston et al., J. Chem. Phys. 98, 4718 (1993)], which predicted no O-CH3 stretch excitation in the methoxy fragment following photolysis of ground state methanol. The spatial anisotropy of the fragments (β˜-0.7) implies a dissociation time ≤1 ps. The impulsive model for rotational excitation is compared to the unresolved rotational contour of the vibrational peaks in the translational energy release spectra and is found to underestimate the extent of rotational excitation, though the model correctly predicts the increase in contour width observed for the O-deuterated species. The unresolved rotational contours are fit empirically. The inferred vibrational energy distributions are discussed in terms of a simple Franck-Condon model for the pseudotriatomic, Me-O-H. Implications of the vibrational and rotational photofragment distributions for the full 1 1A` surface are discussed.

  10. A medium-resolution monochromator for 73 keV x-rays - Nuclear resonant scattering of synchrotron radiation from 193-Ir

    CERN Document Server

    Alexeev, Pavel; Wille, Hans-Christian; Sergeev, Ilya; Herlitschke, Marcus; Leupold, Olaf; McMorrow, Desmond F; Röhlsberger, Ralf

    2016-01-01

    We report on the development and characterization of a medium resolution monochromator for synchrotron-based hyperfine spectroscopy at the 73 keV nuclear resonance of 193-Ir. The device provides high throughput of 6*10^8 ph/s in an energy bandwidth of 300(20) meV. We excited the nuclear resonance in 193-Ir at 73.04 keV and observed nuclear fluorescence of 193-Ir in Iridium metal. The monochromator allows for Nuclear Forward Scattering spectroscopy on Ir and its compounds.

  11. A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.

    Science.gov (United States)

    Wong, Swee Kee; Li, Wenhui; Moore, Michael J; Choe, Hyeryun; Farzan, Michael

    2004-01-30

    The coronavirus spike (S) protein mediates infection of receptor-expressing host cells and is a critical target for antiviral neutralizing antibodies. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for the coronavirus (severe acute respiratory syndrome (SARS)-CoV) that causes SARS. Here we demonstrate that a 193-amino acid fragment of the S protein (residues 318-510) bound ACE2 more efficiently than did the full S1 domain (residues 12-672). Smaller S protein fragments, expressing residues 327-510 or 318-490, did not detectably bind ACE2. A point mutation at aspartic acid 454 abolished association of the full S1 domain and of the 193-residue fragment with ACE2. The 193-residue fragment blocked S protein-mediated infection with an IC(50) of less than 10 nm, whereas the IC(50) of the S1 domain was approximately 50 nm. These data identify an independently folded receptor-binding domain of the SARS-CoV S protein.

  12. Site-specific branching ratios for H-atom production from primary haloalkanes photolyzed at 193, 222, and 248 nm

    Science.gov (United States)

    Brum, Jeffrey L.; Deshmukh, Subhash; Wang, Zhongrui; Koplitz, Brent

    1993-01-01

    Selectively deuterated compounds are used to investigate the ``site-specific'' nature of H-atom production resulting from the photolysis of primary haloalkanes. The molecules investigated are 1-iodopropane, 1-bromopropane, iodoethane, bromoethane, and chloroethane, with photolysis being initiated at 193, 222, and 248 nm. Hydrogen and deuterium isotopes are systematically used to label chemically distinct carbon atoms within a given molecule. H- and D-atom Doppler profiles are generated via two-photon (121.6+364.7 nm) ionization resonant with Lyman-α, and the relative H/D ratios are used to quantify the probability for hydrogen production from each carbon site. In general, photolysis of an intermediate, presumably the alkyl radical, is implicated as being a key step in the overall process. When using 248 nm radiation, the photolysis process is dominated by C-H (or C-D) bond cleavage at the β carbon position regardless of the system investigated. In contrast, results using 193 nm excitation display no obvious preference for bond cleavage at a particular carbon site, again regardless of the system. The data produced by 222 nm photolysis show a qualitative tendency for C-H (or C-D) bond cleavage at the β carbon, but the quantitative results are not as self-consistent as either the 248 nm or the 193 nm data. Also, the results of ab initio calculations on the ground and excited states of the ethyl radical are used to help interpret the observed site specificity.

  13. Analysis of clinical pathological characteristics of 193 gastric polypstreated by endoscopic therapy%胃息肉193例临床病理及内镜治疗分析

    Institute of Scientific and Technical Information of China (English)

    张晓艳; 吴学勇; 吴伟

    2016-01-01

    Objective:To investigate the clinical pathological characteristics .Methods :From 2012 to 2015 .the cases of gastric polyps diagnosed by gastroscopy were collected .Data of gender ,age ,location ,number ,size , pathological type .The data were analyzed by Chisquare test .Results :Among 2003 cases received gastroscopy ,gastric polyps were detected in 193patients and the gastric polyps detection rate was 9 .64% ,which of female(14 .89% ,127/853)was higher than that of male(5 .74% ,66/1150) .And patients aged 50~70 years old has a high prevalence of gastric polyps .The positive rate of H .pylori infection in patients detected with gastric polyp was 12 .70% (321/2 527) .Gastric body(30 .57% ,59/193 )and gastric antrum(25 .91% ,50/193)were two predilection sites of gastric pol‐yps .The common pathological types were hyperplastic polyps65 (33 .68% ) ,inflammatory polyps103 (53 .37% ) , fundicgland polyps 17(8 .81% )and adenomatous polyps 8(4 .15% ) .The treatment of gastric polyps included high frequency electrocoagulation ,argon plasma coagulation ,and endoscopic mucosal resection .gastric polyps were re‐sected in one time ,bleeding occurred after resection treatment to stop bleeding .There was no perforation ,infection , and other complications .Conclusion:The detection elderly woman is at high risk .Hyperplastic and inflammatory polyps ware the most common types .Endoscopic resection could achieve a better curative effect .%目的:探讨胃息肉内镜临床病理特点。方法:对193例胃镜检查发现息肉住院患者回顾性调查其年龄、性别、息肉的部位、数目、大小以及病理分型,并应用统计学进行统计分析。结果:在2003例胃镜检查中发现息肉193例,息肉检出率为9.64%,女性检出率为14.89%(127/853)高于男性(5.74%,66/1150)。以50~70岁患者为高发人群。胃体部(30.57%,59/193)和胃窦部(25.91%,50/193)是胃息肉的两个好发部位

  14. Quantum yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2

    Science.gov (United States)

    Schiffman, A.; Nelson, D. D., Jr.; Nesbitt, D. J.

    1993-05-01

    Flash kinetic spectroscopy in a flow tube is used to measure at room temperature the absolute yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2. The OH radicals are produced by excimer laser photolysis and probed via direct absorption of high resolution tunable IR laser light. The results indicate quantum yields for both precursors at both wavelengths which are less than the maximum possible values of 1 for H2O2. The present measurements are discussed in light of contrasting results suggested from other work.

  15. MicroRNA-193 pro-proliferation effects for bone mesenchymal stem cells after low-level laser irradiation treatment through inhibitor of growth family, member 5.

    Science.gov (United States)

    Wang, Jue; Huang, Weicong; Wu, Yihe; Hou, Jianfeng; Nie, Yu; Gu, Haiyong; Li, Jun; Hu, Shengshou; Zhang, Hao

    2012-09-01

    The enhanced proliferation of mesenchymal stem cells (MSCs) can be helpful for the clinical translation of cell therapy. Low-level laser irradiation (LLLI) has been demonstrated as regulating MSC proliferation. MicroRNAs (miRNAs) are involved in various pathophysiologic processes in stem cells, but the role of miRNAs in the LLLI-based promotion of MSC proliferation remains unclear. We found that the proliferation level and cell cycle-associated genes in MSCs were increased after LLLI treatment in a time-dependent manner. Microarray assays revealed subsets of miRNAs to be differentially regulated, and these dynamic changes were confirmed by quantitative real-time polymerase chain reaction (qRT-PCR) after LLLI. miR-193 was the most highly up-regulated miRNA, and the change in it was related with the proliferation level. Gain-loss function experiments demonstrated that miR-193 could regulate the proliferation of MSCs, including human's and rat's, but could not affect the apoptosis and differentiation level. Blockade of miR-193 repressed the MSC proliferation induced by LLLI. By qRT-PCR, we found that miR-193, in particular, regulated cyclin-dependent kinase 2 (CDK2) expression. Bioinformatic analyses and luciferase reporter assays revealed that inhibitor of growth family, member 5 (ING5) could be the best target of miR-193 to functionally regulate proliferation and CDK2 activity, and the mRNA and protein level of ING5 was regulated by miR-193. Furthermore, the ING5 inhibited by small interfering RNA (siRNA) could up-regulate the proliferation of MSCs and the expression of CDK2. Taken together, these results strongly suggest that miR-193 plays a critical part in MSC proliferation in response to LLLI stimulation, which is potentially amenable to therapeutic manipulation for clinical application.

  16. Photodissociation dynamics of the methyl perthiyl radical at 248 and 193 nm using fast-beam photofragment translational spectroscopy

    Science.gov (United States)

    Harrison, Aaron W.; Ryazanov, Mikhail; Sullivan, Erin N.; Neumark, Daniel M.

    2016-07-01

    The photodissociation dynamics of the methyl perthiyl radical (CH3SS) have been investigated using fast-beam coincidence translational spectroscopy. Methyl perthiyl radicals were produced by photodetachment of the CH3SS- anion followed by photodissociation at 248 nm (5.0 eV) and 193 nm (6.4 eV). Photofragment mass distributions and translational energy distributions were measured at each dissociation wavelength. Experimental results show S atom loss as the dominant (96%) dissociation channel at 248 nm with a near parallel, anisotropic angular distribution and translational energy peaking near the maximal energy available to ground state CH3S and S fragments, indicating that the dissociation occurs along a repulsive excited state. At 193 nm, S atom loss remains the major fragmentation channel, although S2 loss becomes more competitive and constitutes 32% of the fragmentation. The translational energy distributions for both channels are very broad at this wavelength, suggesting the formation of the S2 and S atom products in several excited electronic states.

  17. 复方黄黛片诱导治疗急性早幼粒细胞白血病193例疗效分析%Compound huangdai tablet as induction therapy for 193 patients with acute promyelocytic leukemia

    Institute of Scientific and Technical Information of China (English)

    向阳; 王晓波; 孙淑君; 郭爱霞; 魏艾红; 成玉斌; 黄世林

    2009-01-01

    Objective To report the results of curative and adverse effects of compound huangdai tablet (CHl)T)as induction therapy for 193 patients with acute promyelocytic leukemia(APL). Methods CHDT was administered 1.25 g orally three times a day after meal for three days, then the dosage was gradu-ally increased to 7.5 g/d. Results One hundred and ninety-three patients achieved complete remission (CR) ,78.8% of whom in 30 to 60 days with an average time of 44.3 d. No serious infection, bleeding or D1C occurred during the treatment course. The major adverse effects were gastrointestinal symptoms. There was no change in lanine transaminase, urea, creatinine or electrocardiographic QTc interval in 110 APL pa-tients observed before and after the treatment. Conclusion CHDT therapy is a modality of higher CR rate, good safety and tolerance without bone marrow suppression for APL patients.%目的 总结复方黄黛片诱导治疗193例急性早幼粒细胞白血病(APL)患者的疗效与不良反应.方法 复方黄黛片1.25 g,每日3次,饭后服;3 d后逐渐增量至7.5 g/d.结果 193例患者均获完全缓解(CR),其中78.8%的患者在用药44.3(31~60)d后获CR;疗程中未出现严重的感染、出血,不诱发与加重DIC.治疗中的主要不良反应是胃肠道症状.110例患者治疗前后的丙氨酸转氨酶、尿素、肌酐、心电图的QTc间期等指标变化不大.结论 复方黄黛片治疗APL具有CR率高,不抑制骨髓,不诱发与加重DIC,使用安全,患者耐受性好等特点.

  18. Detection of exosomal microRNA-193b in patients of Alzheimer′s disease%外吐小体内 microRN A-193b 在阿尔茨海默病患者中的检测

    Institute of Scientific and Technical Information of China (English)

    刘辰庚; 张跃其; 王金玲; 王培昌

    2015-01-01

    目的:初步探讨 microRNA‐193b(miR‐193b)作为阿尔茨海默病(AD)生物标志物的潜在价值。方法使用超速离心法提取痴呆期AD(DAT )患者和轻度认知障碍(MCI)患者和健康对照组血清和脑脊液外吐小体并检测其miR‐193b水平。结果 MCI和DAT患者脑脊液及血清外吐小体内miR‐193b水平均低于对照组(P<0.05),且DAT组低于MCI组,差异均有统计学意义(P<0.05)。结论脑脊液和血清外吐小体内miR‐193b可能为AD ,特别是早期诊断AD的标志物。%Objective To evaluate the potential value of microRNA‐193b(miR‐193b) as a biomarker in Alzhei‐mer′s disease(AD) .Methods The super centrifugation method was adopted to extract the exosome from serum and cerebrospinal fluid and the level of exosomal miR‐193b was detected in the patients with mild cognitive impairment (MCI) ,patients with dementia of Alzheimer′s type(DAT ) and healthy control group .Results The exosomal miR‐193b levels in cerebrospinal fluid of the patients with MCI and DAT were significantly higher than that of the control (P<0 .05) ,moreover the DAT group was lower than the MCI group(P<0 .05) .The exosomal miR‐193b levels in serum of the patients with MCI and DAT were significantly lower than that of the control group(P<0 .05) .Conclu‐sion The exosomal miR‐193b in serum and cerebrospinal fluid may be a potential biomarker of AD ,especially for its early stage .

  19. $Upsilon$ production in U + U collisions at $\\sqrt{s_{NN}}$=193 GeV measured with the STAR experiment

    CERN Document Server

    Adamczyk, L.

    2016-01-01

    We present a measurement of the inclusive production of Upsilon mesons in U+U collisions at 193 GeV at mid-rapidity (|y| < 1). Previous studies in central Au+Au collisions at 200 GeV show a suppression of Upsilon(1S+2S+3S) production relative to expectations from the Upsilon yield in p+p collisions scaled by the number of binary nucleon-nucleon collisions (Ncoll), with an indication that the Upsilon(1S) state is also suppressed. The present measurement extends the number of participant nucleons in the collision (Npart) by 20% compared to Au+Au collisions, and allows us to study a system with higher energy density. We observe a suppression in both the Upsilon(1S+2S+3S) and Upsilon(1S) yields in central U+U data, which consolidates and extends the previously observed suppression trend in Au+Au collisions.

  20. Photolytic decomposition of adsorbed tellurium and cadmium alkyl species at 295 K upon 193 nm photon irradiation

    Science.gov (United States)

    Stinespring, C. D.; Freedman, A.

    1988-06-01

    The photolytic decomposition of adspecies formed by the adsorption of tellurium and cadmium alkyls at 295 K under ultrahigh-vacuum conditions has been studied using x-ray photoelectron spectroscopy. Dimethyl tellurium adsorbed at submonolayer coverages on a polycrystalline gold substrate has been observed to undergo nearly quantitative photolytic decomposition at 193 nm to form metallic tellurium. The hydrocarbon photofragments produced in the decomposition lead to negligible carbon contamination on the gold surface. Dimethyl cadmium adsorbed on amorphous SiO2 both desorbs and decomposes to form the metal adspecies. In this case, most of the carbon remains as hydrocarbon and carbidic contaminants. Monomethyl adspecies of both metals formed on Si(100) and GaAs(100) surfaces are inactive with respect to decomposition at the low fluences (0.25 mJ cm-2) used in these experiments; however, substantial desorption is observed.

  1. Simulation study of the NA/σ's dependence of DOF for 193-nm immersion lithography at 65-nm node

    Institute of Scientific and Technical Information of China (English)

    Guosheng Huang; Yanqiu Li

    2005-01-01

    @@ Recently, ArF immersion lithography has been considered as a promising method after ArF dry lithography by a factor of refractive index n of the liquid filled into the space between the bottom lens and wafer,in the case of 193-nm exposure tools, water (n = 1.44) has been found as the best liquid. We explore the NA/σ's dependence of depth of focus (DOF) under 3/4 annular and 3/4 quasar illumination by resist Finally, we explored the high NA's dependency of DOF and gave the explanation for the peak value of DOF through three-beam imaging process, MicroCruiser 2.0, Prolith version 8.0.2 and k2 factor based on the Rayleigh equation.

  2. 北京市新中街社区193名老年人认知功能状况的调查%Cognitive function status among 193 elders in the Xinzhongjie Community Beijing

    Institute of Scientific and Technical Information of China (English)

    吴文静; 刘宇; 彭荣立; 夏芸

    2015-01-01

    Objective To probe into the cognitive function among elders in Xinzhongjie community and provide the evidence for corresponding nursing interventions. Methods Convenient sampling was used to recruit 193 elders who were equal to or older than 60 for the investigation by Montreal cognitive assessment ( MoCA) . Results There were 37 elders (19. 17%) who were abnormal on cognitive function. Cognitive function was related to age, educational level, and whether had brain disease. Elders, who were in older, with lower educational level, and had brain disease, were more frequently to have abnormal cognitive function (χ2 =9. 54, 20. 58,21. 92;P<0. 01). By Logistic regression analysis, older age and brain disease were risk factors for cognitive function declines, while high educational level was a protective factor for the cognitive function. Conclusions Community nurses should pay increasing attention on the changes of cognitive function among elders who are in older age, with lower educational level, and have brain disease. Non-pharmacological nursing intervention can be provided to elders according to their specific cognitive function decline.%目的:了解社区老年人的认知功能状况,为相应的社区护理措施提供依据。方法采用蒙特利尔( MoCA)认知功能评估量表对北京新中街社区内能合作的193名60岁及以上的老年人进行调查。结果193名老年人中有37名出现认知功能异常,占19.17%;认知功能是否正常与老人的年龄分布、教育程度、是否患有脑部疾病因素有关,高龄组老人、低学历、既往患有脑部疾病的老人中认知功能异常的人数多(χ2值分别为9.54,20.58,21.92;P<0.01);Logistic回归分析显示,高龄和既往患有脑部疾病是老年人发生认知功能异常的危险因素,而高学历是老年人认知功能的保护因素。结论社区护士要特别关注高龄、低教育程度、既往患有脑部疾病的老人的认知功能变化情况;

  3. 33 CFR 207.170d - Taylor Creek, navigation lock (S-193) across the entrance to Taylor Creek at Lake Okeechobee...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Taylor Creek, navigation lock (S-193) across the entrance to Taylor Creek at Lake Okeechobee, Okeechobee, Fla.; use, administration..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.170d Taylor Creek, navigation...

  4. Investigation of the use of an {alpha} + Xn reaction channel to enhance the population of superdeformed states in {sup 193}Hg and {sup 195}Hg

    Energy Technology Data Exchange (ETDEWEB)

    Zwartz, G.; Drake, T.E.; Cromaz, M. [Department of Physics, University of Toronto, Toronto, Ontario M5S-1A7 (Canada); Ward, D.; Janzen, V.; Galindo-Uribarri, A. [Chalk River Laboratories, Chalk River, Ontario K0J-1J0 (Canada); Prevost, D.; Waddington, J.; Mullins, S.M. [Department of Physics and Astronomy, McMaster University, Hamilton, Ontario L8S-4K1 (Canada)

    2000-11-01

    A study was made to determine whether the population of superdeformed states in {sup 193}Hg and {sup 195}Hg can be enhanced by using reactions in which alpha particles are emitted. The search utilized a {sup 184}W({sup 18}O,{alpha} Xn) reaction at 115 and 120 MeV for the {sup 193}Hg study and a {sup 186}W({sup 18}O,{alpha} Xn) reaction at 105 and 110 MeV for the {sup 195}Hg study. Two known superdeformed states of {sup 193}Hg were observed. The intensities of the superdeformed states in {sup 193}Hg populated by a reaction involving the emission of an alpha particle were found to be reduced by at least a factor of four relative to the intensities of these states produced in reactions involving only the emission of neutrons and {gamma}-rays. No rotational bands built on superdeformed states in {sup 195}Hg with transition intensities >0.8% of the total {sup 195}Hg yield were found. Evidence is shown that the energy of the alpha particle that is associated with superdeformed states may be lower than that of alpha particles associated with normally deformed states. (author)

  5. A preliminary study of the role of miR-193a-3p in radioresistance of esophageal cancer cells%miR-193a-3p在食管癌细胞放射抵抗作用的初步研究

    Institute of Scientific and Technical Information of China (English)

    孟芳; 钱立庭; 丁伯金; 周解平

    2016-01-01

    目的:探讨miR⁃193a⁃3p在食管鳞癌放射耐受性机制中的作用。方法通过6 MV X射线对4个食管癌细胞系进行照射,采用MTT法检测出相对敏感系及耐受系细胞;茎环引物实时定量PCR法检测miR⁃193a⁃3p、miR⁃155、miR⁃22⁃3p在2个细胞中的表达,miR⁃193a⁃3p作为表达差异较为明显的 microRNA 被挑选进行下一步研究。分别合成并转染 miR⁃193a⁃3p 的 mimic (3PM)或antagomiR (3PA)序列及小干扰RNA (si⁃LOXL4)以提高或抑制其在细胞中的表达水平,MTT法和流式细胞分析术检测miR⁃193a⁃3p及其下游基因LOXL4对于放射敏感性的影响。结果筛选出相对放射敏感细胞系( KYSE510)及耐受细胞系( KYSE410);miR⁃193a⁃3p在两系细胞中的表达水平差异显著高于miR⁃155、miR⁃22⁃3p (1.00∶21.13);KYSE510细胞中转染mimic提高其表达后,与对照组相比,其放射敏感性降低,细胞凋亡比例显著下降11.10%(P<0.05),而 KYSE410细胞中转染 antagomiR后,其敏感性增加( P<0.05)。作为miR⁃193a⁃3p的下游基因,LOXL4的表达抑制也受到miR⁃193a⁃3p的调控,转染si⁃LOXL4降低其表达,与对照组相比放射敏感性也降低,细胞凋亡比例下降7.07%( P<0.05)。结论 miR⁃193a⁃3p可能通过调控基因LOXL4促进食管癌细胞放射耐受性。%Objective To investigate the role of miR⁃193a⁃3p in the radioresistance of esophageal squamous cell carcinoma ( ESCC) . Methods MTT assay was used to identify the cell lines with the highest radiosensitivity and radioresistance in four esophageal cancer cell lines exposed to irradiation of 6 MV X⁃ray. Stem⁃loop quantitative real⁃time PCR was used to measure the expression levels of miR⁃193a⁃3p, miR⁃155, and miR⁃22⁃3P in the two cell lines. Further studies were performed on miR⁃193a⁃3p because of the substantial difference in its expression between

  6. Translational energy distribution from C sub 2 H sub 2 + hv(193. 3 nm) yields C sub 2 H + H

    Energy Technology Data Exchange (ETDEWEB)

    Segall, J.; Wen, Y.; Lavi, R.; Singer, R.; Wittig, C. (Univ. of Southern California, Los Angeles (United States))

    1991-10-17

    The authors report the center-of-mass translational energy distribution for 193.3-nm photolysis of expansion-cooled C{sub 2}H{sub 2}, using high-n Rydberg-level excitation of nascent H atoms to facilitate high-resolution time-of-flight measurements. The observed resolution of {approximately}200 cm{sup {minus}1} is presently limited by the ArF photolysis laser, whose band width is approximately 200 cm{sup {minus}1}. The reported distribution clearly resolves a C{sub 2}H bending progression (v{sub 2}{approximately}400 cm{sup {minus}1}), which reflects the trans-bent C{sub 2}H{sub 2} excited state. A definitive assignment of all features is still not possible on the basis of currently available information of C{sub 2}H. These measurements yield an upper bound to D{sub 0} of 131.8 {plus minus} 0.5 kcal mol{sup {minus}1}.

  7. Potential impacts of 40 CFR 193 on the development of low-level radioactive waste disposal facilities

    Energy Technology Data Exchange (ETDEWEB)

    Alvarado, R.A. [Texas Low-Level Radioactive Waste Disposal Authority, Austin, TX (United States)

    1989-11-01

    Since the publication of the Advanced Notice of Proposed Rulemaking in August, 1983, the proposed environmental regulations regarding low-level radioactive waste have become a serious uncertainty in the development of new low-level radioactive waste disposal facilities. The proposed rule has been discussed on several occasions by the Technical Coordinating Committee and the purpose of this paper is to present the results of the Committee`s discussions regarding the proposed rule. The proposed standard has several closely related elements. The rule would prescribe limits on radiation exposure to individuals during processing, management and storage of low-level radioactive waste. It would set BRC levels and also set dose standards for the period following site closure. An important portion of the standard, as far as developing new facilities, is the ground water protection standard. The comments received during developing of 40 CFR 193 has also led the Environmental Protection Agency to propose 40 CFR 764 governing the disposal of naturally occurring radioactive material or NORM.

  8. Effect of water saturation and temperature in the range of 193 to 373 K on the thermal conductivity of sandstone

    Science.gov (United States)

    Guo, P. Y.; Zhang, N.; He, M. C.; Bai, B. H.

    2017-03-01

    The thermal conductivity of porous media is crucial for many geological and engineering projects. Although the thermal conductivity at low temperatures is often overlooked, it is of great significance to calculate the amount of heat that the ice sheet absorbs from the Earth. In this study, the thermal conductivity of dry and water-saturated sandstone was measured in the temperature range of 193 to 373 K using a transient hot wire method. All samples were collected from East China, with a sample porosity distribution of 5 to 13%. The effects of temperature, water saturation and phase transition of fluid in the pores were investigated. The results indicate that the thermal conductivity decreases with an increase in temperature and that the decrease is steeper when the temperature is below 273 K. Moreover, it is found that the thermal conductivity of the saturated sandstone is larger than that of the dry sandstone. With an increase in porosity, the thermal conductivity significantly increases in saturated sandstone but remains almost the same or even decreases in dry sandstones. Finally, it is revealed that the effect of phase transformation on the thermal conductivity is significant. When the water in pores becomes ice, the thermal conductivity increases significantly and increases further as the temperature decreases.

  9. Forward $J/\\psi$ production in U$+$U collisions at $\\sqrt{s_{NN}}$=193 GeV

    CERN Document Server

    Adare, A; Ajitanand, N N; Akiba, Y; Akimoto, R; Alexander, J; Alfred, M; Aoki, K; Apadula, N; Asano, H; Atomssa, E T; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Bai, X; Bandara, N S; Bannier, B; Barish, K N; Bathe, S; Baublis, V; Baumann, C; Baumgart, S; Bazilevsky, A; Beaumier, M; Beckman, S; Belmont, R; Berdnikov, A; Berdnikov, Y; Black, D; Blau, D S; Bok, J S; Boyle, K; Brooks, M L; Bryslawskyj, J; Buesching, H; Bumazhnov, V; Butsyk, S; Campbell, S; Chen, C -H; Chi, C Y; Chiu, M; Choi, I J; Choi, J B; Choi, S; Christiansen, P; Chujo, T; Cianciolo, V; Citron, Z; Cole, B A; Cronin, N; Crossette, N; Csanád, M; Csörgő, T; Danley, D; Datta, A; Daugherity, M S; David, G; DeBlasio, K; Dehmelt, K; Denisov, A; Deshpande, A; Desmond, E J; Ding, L; Dion, A; Diss, P B; Do, J H; D'Orazio, L; Drapier, O; Drees, A; Drees, K A; Durham, J M; Durum, A; Engelmore, T; Enokizono, A; Esumi, S; Eyser, K O; Fadem, B; Feege, N; Fields, D E; Finger, M; Jr., \\,; Fleuret, F; Fokin, S L; Frantz, J E; Franz, A; Frawley, A D; Fukao, Y; Fusayasu, T; Gainey, K; Gal, C; Gallus, P; Garg, P; Garishvili, A; Garishvili, I; Ge, H; Giordano, F; Glenn, A; Gong, X; Gonin, M; Goto, Y; de Cassagnac, R Granier; Grau, N; Greene, S V; Perdekamp, M Grosse; Gu, Y; Gunji, T; Guragain, H; Hachiya, T; Haggerty, J S; Hahn, K I; Hamagaki, H; Hamilton, H F; Han, S Y; Hanks, J; Hasegawa, S; Haseler, T O S; Hashimoto, K; Hayano, R; He, X; Hemmick, T K; Hester, T; Hill, J C; Hollis, R S; Homma, K; Hong, B; Hoshino, T; Hotvedt, N; Huang, J; Huang, S; Ichihara, T; Ikeda, Y; Imai, K; Imazu, Y; Inaba, M; Iordanova, A; Isenhower, D; Isinhue, A; Ivanishchev, D; Jacak, B V; Jeon, S J; Jezghani, M; Jia, J; Jiang, X; Johnson, B M; Joo, K S; Jouan, D; Jumper, D S; Kamin, J; Kanda, S; Kang, B H; Kang, J H; Kang, J S; Kapustinsky, J; Kawall, D; Kazantsev, A V; Key, J A; Khachatryan, V; Khandai, P K; Khanzadeev, A; Kijima, K M; Kim, C; Kim, D J; Kim, E -J; Kim, G W; Kim, M; Kim, Y -J; Kim, Y K; Kimelman, B; Kistenev, E; Kitamura, R; Klatsky, J; Kleinjan, D; Kline, P; Koblesky, T; Kofarago, M; Komkov, B; Koster, J; Kotchetkov, D; Kotov, D; Krizek, F; Kurita, K; Kurosawa, M; Kwon, Y; Lacey, R; Lai, Y S; Lajoie, J G; Lebedev, A; Lee, D M; Lee, G H; Lee, J; Lee, K B; Lee, K S; Lee, S; Lee, S H; Leitch, M J; Leitgab, M; Lewis, B; Li, X; Lim, S H; Liu, M X; Lynch, D; Maguire, C F; Makdisi, Y I; Makek, M; Manion, A; Manko, V I; Mannel, E; Maruyama, T; McCumber, M; McGaughey, P L; McGlinchey, D; McKinney, C; Meles, A; Mendoza, M; Meredith, B; Miake, Y; Mibe, T; Mignerey, A C; Milov, A; Mishra, D K; Mitchell, J T; Miyasaka, S; Mizuno, S; Mohanty, A K; Mohapatra, S; Montuenga, P; Moon, T; Morrison, D P; Moskowitz, M; Moukhanova, T V; Murakami, T; Murata, J; Mwai, A; Nagae, T; Nagamiya, S; Nagashima, K; Nagle, J L; Nagy, M I; Nakagawa, I; Nakagomi, H; Nakamiya, Y; Nakamura, K R; Nakamura, T; Nakano, K; Nattrass, C; Netrakanti, P K; Nihashi, M; Niida, T; Nishimura, S; Nouicer, R; Novak, T; Novitzky, N; Nyanin, A S; O'Brien, E; Ogilvie, C A; Oide, H; Okada, K; Koop, J D Orjuela; Osborn, J D; Oskarsson, A; Ozawa, K; Pak, R; Pantuev, V; Papavassiliou, V; Park, I H; Park, J S; Park, S; Park, S K; Pate, S F; Patel, L; Patel, M; Peng, J -C; Perepelitsa, D V; Perera, G D N; Peressounko, D Yu; Perry, J; Petti, R; Pinkenburg, C; Pinson, R; Pisani, R P; Purschke, M L; Qu, H; Rak, J; Ramson, B J; Ravinovich, I; Read, K F; Reynolds, D; Riabov, V; Riabov, Y; Richardson, E; Rinn, T; Riveli, N; Roach, D; Rolnick, S D; Rosati, M; Rowan, Z; Rubin, J G; Ryu, M S; Sahlmueller, B; Saito, N; Sakaguchi, T; Sako, H; Samsonov, V; Sarsour, M; Sato, S; Sawada, S; Schaefer, B; Schmoll, B K; Sedgwick, K; Seele, J; Seidl, R; Sekiguchi, Y; Sen, A; Seto, R; Sett, P; Sexton, A; Sharma, D; Shaver, A; Shein, I; Shibata, T -A; Shigaki, K; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Singh, B K; Singh, C P; Singh, V; Skolnik, M; Slunečka, M; Snowball, M; Solano, S; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Stankus, P W; Steinberg, P; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Stone, M R; Sugitate, T; Sukhanov, A; Sumita, T; Sun, J; Sziklai, J; Takahara, A; Taketani, A; Tanaka, Y; Tanida, K; Tannenbaum, M J; Tarafdar, S; Taranenko, A; Tennant, E; Tieulent, R; Timilsina, A; Todoroki, T; Tomášek, M; Torii, H; Towell, C L; Towell, R; Towell, R S; Tserruya, I; van Hecke, H W; Vargyas, M; Vazquez-Zambrano, E; Veicht, A; Velkovska, J; Vértesi, R; Virius, M; Vrba, V; Vznuzdaev, E; Wang, X R; Watanabe, D; Watanabe, K; Watanabe, Y; Watanabe, Y S; Wei, F; Whitaker, S; White, A S; Wolin, S; Woody, C L; Wysocki, M; Xia, B; Xue, L; Yalcin, S; Yamaguchi, Y L; Yanovich, A; Yokkaichi, S; Yoo, J H; Yoon, I; You, Z; Younus, I; Yu, H; Yushmanov, I E; Zajc, W A; Zelenski, A; Zhou, S; Zou, L

    2015-01-01

    The invariant yields for $J/\\psi$ production at forward rapidity $(1.2<|y|<2.2)$ in U$+$U collisions at $\\sqrt{s_{_{NN}}}$=193 GeV have been measured as a function of collision centrality. The invariant yields and nuclear-modification factor $R_{AA}$ are presented and compared with those from Au$+$Au collisions in the same rapidity range. Additionally, the direct ratio of the invariant yields from U$+$U and Au$+$Au collisions within the same centrality class is presented, and used to investigate the role of $c\\bar{c}$ coalescence. Two different parameterizations of the deformed Woods-Saxon distribution were used in Glauber calculations to determine the values of the number of nucleon-nucleon collisions in each centrality class, $N_{\\rm coll}$, and these were found to give significantly different $N_{\\rm coll}$ values. Results using $N_{\\rm coll}$ values from both deformed Woods-Saxon distributions are presented. The measured ratios show that the $J/\\psi$ suppression, relative to binary collision scaling...

  10. Electro-optical and dielectric properties of a high tilt antiferroelectric liquid crystal mixture (W-193B)

    Energy Technology Data Exchange (ETDEWEB)

    Nayek, Prasenjit; Ghosh, Sharmistha; Kundu, Sudarshan; Roy, Subir Kr [Department of Spectroscopy, Indian Association for the Cultivation of Science, Jadavpur, Calcutta-700032 (India); Majumder, Tapas Pal [Department of Physics, University of Kalyani, Kalyani-741235, West Bengal (India); Bennis, Noureddine; Oton, Jose Manuel [Department of TecnologIa Fotonica, ETSI Telecomunicacion, Universidad Politecnica de Madrid, Ciudad Universitaria, 28040 Madrid (Spain); Dabrowski, Roman, E-mail: spskr@iacs.res.i [Institute of Chemistry, Military University of Technology, 00-908 Warsaw (Poland)

    2009-11-21

    The electro-optical properties and dielectric relaxation have been investigated for an antiferroelectric liquid crystal mixture W-193B. The material exhibits smectic A*, smectic C* and a wide range of anticlinic smectic C{sub A}{sup *} phases. The high tilt and broad room temperature smectic C{sub A}{sup *} phase make it a good candidate for antiferroelectric display materials. Dielectric studies have been made in a planarly aligned cell in the frequency range 10 Hz-13 MHz. Dielectric spectroscopy reveals the existence of soft mode in the smectic A* phase and Goldstone mode in the smectic C* phase. In the smectic C{sub A}{sup *} phase the dielectric spectrum of the material exhibits two absorption peaks related to the rotational fluctuation around the short axis of the molecules and antiphase azimuthal angle fluctuation, respectively, and are separated by about two orders of frequency. Electro-optical response using a low frequency triangular wave showed a very high quasi-static contrast ratio of 132 : 1, threshold voltage of around 7 V and saturation of 17 V. Surface-stabilized, low thickness cells of this mixture showed a perfect double hysteresis loop with a 1 Hz triangular signal, reaching different transmission levels for different voltage amplitudes. These levels can be stabilized with a single holding voltage, making it possible for the material to be passively multiplexed at video rate.

  11. STAR measurements of elliptic flow in U+U collisions at √sNN = 193 GeV

    Science.gov (United States)

    Callister, Thomas

    2012-10-01

    The hot, dense nuclear medium created in Au+Au collisions at RHIC has exhibited strong, anisotropic collective motion, characterized by the elliptic flow v2. v2has been extensively studied, and is thought to be related to the initial eccentricity of the colliding system and the parton density, quantified by 1/S*dN/dy. Collisions of heavier, deformed uranium nuclei will introduce different eccentricities, and will increase the achievable value of 1/S*dN/dy by 13% [1]. Simulations therefore predict central U+U collisions to yield a significant increase in v2over central Au+Au collisions [2], and also predict a cusp structure in v2vs. multiplicity due to the deformation of uranium [3]. STAR has taken data of U+U collisions at √sNN = 193 GeV in RHIC run2012. In this poster we present preliminary STAR measurements of v2from these collisions. Physics implications of our measurements will also be discussed.[4pt] [1] C. Nepali, G. Fai, and D. Keane, Phys. Rev. C73 (2006) 034911.[0pt] [2] H. Masui, B. Mohanty, N. Xu, Phys. Lett. B679 (2009) 440.[0pt] [3] S. Voloshin, Phys. Rev. Lett.105 (2010) 172301.

  12. 助产士主导伙伴式导乐陪伴分娩193例临床观察%Clinical Observation of 193 Cases of Midwife-Led Partnership-Based Doula Childbirth

    Institute of Scientific and Technical Information of China (English)

    杨欢秀; 欧阳友云; 杨璠

    2013-01-01

    Objective:To investigate the clinical results of midwife-led partnership-based doula childbirth.Method:Three hundred and eighty-six cases of maternal childbirth from August 2010 to August 2012 in the hospital were randomly divided into the observation group and the control group, each group of 193 cases. The control group received routine maternity care measures,the observation group on the basis of routine nursing mothers were given partnership-Doula,compared two groups of maternal mode of delivery,postpartum hemorrhage,neonatal asphyxia rate and the total process time.Result:The natural childbirth of the study group was 90.7%while the control group was 65.1%,and the difference between the two groups were statistically significant(P<0.05). The observation group of postpartum hemorrhage,neonatal asphyxia rate and total production process time were significantly lower than the control group,and all the difference between the two groups were statistically significant(P<0.05).Conclusion:Applied midwife-led maternity partnership type Doula,can effectively improve the natural birth rate,shorten the production process,reduce the rate of postpartum hemorrhage and neonatal asphyxia,worthy of clinical application and promotion.%目的:探讨助产士主导伙伴式导乐陪伴分娩的临床效果。方法:选取2010年8月-2012年8月在本院分娩的386例产妇,按照随机数字表法将其分为观察组和对照组各193例。对照组产妇给予常规护理措施,观察组产妇在常规护理基础上加以伙伴式导乐陪伴分娩,比较两组产妇分娩方式、产后出血率、新生儿窒息率及总产程时间。结果:观察组自然分娩率为84.5%,对照组自然分娩率为65.3%;观察组自然分娩率显著高于对照组(P<0.05);观察组产妇产后出血率、新生儿窒息率及总产程时间均显著低于对照组(P<0.05)。结论:在产妇分娩时应用助产士主导伙伴式导乐分娩,可有效提高自

  13. 193 cases with sex developing abnormality were checked out cytogenetical examination and clinical analysis%193例性分化异常病人的细胞遗传学检查和临床分析

    Institute of Scientific and Technical Information of China (English)

    王健; 丁显平; 袁蔓莉

    2005-01-01

    目的对性分化异常病人的细胞遗传学和临床诊断治疗,发病原因进行分析和探讨.方法重点对193例性分化异常病人进行外周血染色体分析,同时对病史,体格检查做详细的记录,以及相应的生化检查.结果染色体异常有67例,占总数的34.72%,其中Tumer's综合征和Klinefelter's综合征分别为34例和23例.为最常见的染色体异常,分别占就诊总数的17.62%和11.92%.XXX综合征4例,2.07%,性反转综合征2例,真两性畸形2例,另有2例为常染色体异常,各占1.04%.非染色体异常的疾病中以46,XX单纯性腺发育不良为最常见112例,58.03%.结论对性分化异常病人进行染色体检查非常必要,对诊断和治疗有重要意义.早期检查和分析尤为重要.

  14. 193例45岁以下的下肢缺血患者病因及诊治分析%Diagnosis and treatment of 193 cases under 45 years old with peripheral arterial disease

    Institute of Scientific and Technical Information of China (English)

    倪冷; 刘昌伟; 刘暴; 叶炜; 吴巍巍; 宋小军; 管珩

    2010-01-01

    Objective To analyze the etiology,characteristics,and treatment outcomes of peripheral arterial disease (PAD) in patients under 45 years old.Methods One hundred and ninety-three cases mader 45 years old with PAD were included from January 1999 to January 2009.The demography. etiology,surgical data,treatment outcomes of these patients were evaluated and analyzed.Among these patients,males are 171 cases.The age was 13 to 44 years old (average age 35 years old) and the average time between onsets of PAD to admission was 3.6 months.In the 138 patients who underwent surgical interventions,30 patients had serologieally proven thrombophilia,50 patients without thrombophilia had other definite reasons but not Burger's disease.A total of 116 cases underwent open operations,17 cases were received endovascular interventions and 5 cases underwent combinative treatments.Results Among the 193 patients,140 cases(72.5%)had definite reafons.Forty patients(28.6%)were diagnosed with congenital or acquired hypercoagulability in the 140 cases.The thrombophilia group had poorer primary patency(70.0% vs.92.0%,P=0.010) and secondary patency(83.3% vs.98.0%,P=0.016) than non-thrombophilia group and more likely to underwent second revascularization because of recurrent thrombosis within 30 days after operations.After 16 months follow-up, the patients with thrombophilia had lower primary pateney(65.0% vs.75.7%,P=0.392) and secondary pateney(80.0%vs.91.9%,P= 0.192) than the ones without thrombophilia and the rate of ampumtion was higher in thrombophilia group (15.0% vs.5.4%.P=0.222) but,these didn't achieve statistical significance.Conclusions A high prevalence rate of thrombophilia is found in patients less than 45 years old with PAD requiring revascularization.Thrombophilia may have contributed to early postoperative thrombosis of the vascular procedure So the screening and medical therapy to thmmbophilia in young adults with PAD should be reinforced before surgical treatment.%目的 探讨

  15. Kinetics of the Reaction C2H + O2 from 193 to 350 K Using Laser Flash Kinetic Infrared Absorption Spectroscopy

    Science.gov (United States)

    Opansky, Brian J.; Seakins, Paul W.; Pedersen, Jens Olaf P.; Leone, Stephen R.

    1993-01-01

    Rate coefficients for the reaction C2H + O2 are measured from 193 to 350 K by using transient absorption spectroscopy with an infrared color center laser. Ethynyl radicals are produced by pulsed laser photolysis of C2H2 in a temperature variable flow cell and a tunable color center laser probes the transient removal Of C2H ((bar-X(sup 2))Sigma(+))(0,0,0)) in absorption. The rate coefficient has a slight negative temperature dependence over the range 193-350 K which can be expressed as k(O2) = (1.5 +/- 0.3) x 10(exp -11) exp((230 +/- 36)/T) Cu cm/(Molecule.s). The lack of a pressure dependence under our experimental conditions strongly suggests that the HCCOO* complex is short lived with respect to encountering a collision and rapidly dissociates to products without competition from collisional stabilization to HCCOO or collisionally induced dissociation to reactants.

  16. Clinical significance of miR-140-5p and miR-193b expression in patients with breast cancer and relationship to IGFBP5

    Directory of Open Access Journals (Sweden)

    Gökçe Güllü

    2015-03-01

    Full Text Available The functional role of IGFBP5 in breast cancer is complicated. Experimental and bioinformatics studies have shown that IGFBP5 is targeted by miR-140-5p and miR-193b, although this has not yet been proven in clinical samples. The aim of this study was to evaluate the expression of miR-140-5p and miR-193b in breast cancer and adjacent normal tissue and assess its correlation with IGFBP5 and the clinicopathological characteristics of the tumors. IGFBP5 protein expression was analyzed immunohistochemically and IGFBP5, miR-140 and miR-193b mRNA expression levels were analyzed with real-time RT-PCR. Tumor tissue had higher miR-140-5p expression than adjacent normal tissue (p = 0.015. Samples with no immunohistochemical staining for IGFBP5 showed increased miR-140-5p expression (p = 0.009. miR-140-5p expression was elevated in invasive ductal carcinomas (p = 0.002, whereas basal-like tumors had decreased expression of miR-140-5p compared to other tumors (p = 0.008. Lymph node-positive samples showed an approximately 13-fold increase in miR-140-5p expression compared to lymph node-negative tissue (p = 0.049. These findings suggest that miR-140-5p, but not miR-193b, could be an important determinant of IGFBP5 expression and clinical phenotype in breast cancer patients. Further studies are needed to clarify the expressional regulation of IGFBP5 by miR-140-5p.

  17. Low-dose irradiation promotes Rad51 expression by down-regulating miR-193b-3p in hepatocytes

    Science.gov (United States)

    Lee, Eon-Seok; Won, Yeo Jin; Kim, Byoung-Chul; Park, Daeui; Bae, Jin-Han; Park, Seong-Joon; Noh, Sung Jin; Kang, Yeong-Rok; Choi, Si Ho; Yoon, Je-Hyun; Heo, Kyu; Yang, Kwangmo; Son, Tae Gen

    2016-05-01

    Current evidence indicates that there is a relationship between microRNA (miRNA)-mediated gene silencing and low-dose irradiation (LDIR) responses. Here, alterations of miRNA expression in response to LDIR exposure in male BALB/c mice and three different types of hepatocytes were investigated. The miRNome of the LDIR-exposed mouse spleens (0.01 Gy, 6.5 mGy/h) was analyzed, and the expression of miRNA and mRNA was validated by qRT-PCR. Western blotting, chromatin immunoprecipitation (ChIP), and luciferase assays were also performed to evaluate the interaction between miRNAs and their target genes and to gain insight into the regulation of miRNA expression. The expression of miRNA-193b-3p was down-regulated in the mouse spleen and liver and in various hepatocytes (NCTC, Hepa, and HepG2 cell lines) in response to LDIR. The down-regulation of miR-193b-3p expression was caused by histone deacetylation on the miR-193b-3p promoter in the HepG2 cells irradiated with 0.01 Gy. However, the alteration of histone deacetylation and miR-193b-3p and Rad51 expression in response to LDIR was restored by pretreatment with N-acetyl-cyctein. In conclusion, we provide evidence that miRNA responses to LDIR include the modulation of cellular stress responses and repair mechanisms.

  18. Point mutation in the NF2 gene of HEI-193 human schwannoma cells results in the expression of a merlin isoform with attenuated growth suppressive activity

    Energy Technology Data Exchange (ETDEWEB)

    Lepont, Pierig; Stickney, John T.; Foster, Lauren A.; Meng, Jin-Jun; Hennigan, Robert F. [Department of Cell and Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, 3125 Eden Avenue, Cincinnati, OH 45267-0521 (United States); Ip, Wallace [Department of Cell and Cancer Biology, Vontz Center for Molecular Studies, University of Cincinnati College of Medicine, 3125 Eden Avenue, Cincinnati, OH 45267-0521 (United States)], E-mail: wallace.ip@uc.edu

    2008-01-01

    Neurofibromatosis type 2 (NF2) is a genetic disorder characterized by the formation of bilateral schwannomas of the eighth cranial nerve. Although the protein product of the NF2 gene (merlin) is a classical tumor suppressor, the mechanism by which merlin suppresses cell proliferation is not fully understood. The availability of isolated tumor cells would facilitate a better understanding of the molecular function of merlin, but primary schwannoma cells obtained from patients grow slowly and do not yield adequate numbers for biochemical analysis. In this study, we have examined the NF2 mutation in HEI-193 cells, an immortalized cell line derived from the schwannoma of an NF2 patient. Previous work showed that the NF2 mutation in HEI-193 cells causes a splicing defect in the NF2 transcript. We have confirmed this result and further identified the resultant protein product as an isoform of merlin previously designated as isoform 3. The level of isoform 3 proteins in HEI-193 cells is comparable to the levels of merlin isoforms 1 and 2 in normal human Schwann cells and several other immortalized cell lines. In contrast to many mutant forms of merlin, isoform 3 is as resistant to proteasomal degradation as isoforms 1 and 2 and can interact with each of these isoforms in vivo. Cell proliferation assays showed that, in NF2{sup -/-} mouse embryonic fibroblasts, exogenously expressed merlin isoform 3 does exhibit growth suppressive activity although it is significantly lower than that of identically expressed merlin isoform 1. These results indicate that, although HEI-193 cells have undetectable levels of merlin isoforms 1 and 2, they are, in fact, not a merlin-null model because they express the moderately active growth suppressive merlin isoform 3.

  19. Hydrothermal Alteration in the PACMANUS Hydrothermal Field: Implications From Secondary Mineral Assemblages and Mineral Chemistry, OPD Leg 193

    Science.gov (United States)

    Lackschewitz, K. S.; Kummetz, M.; Kummetz, M.; Ackermand, D.; Botz, R.; Devey, C. W.; Singer, A.; Stoffers, P.

    2001-12-01

    Leg 193 of the Ocean Drilling Program investigated the subsurface nature of the active PACMANUS hydrothermal field in the Manus backarc basin near Papua New Guinea. Drilling in different areas on the felsic neovolcanic Pual Ridge, including the high-temperature black smoker complex of Roman Ruins and the low-temperature Snowcap site with diffusive discharge yielded a complex alteration history with a regional primary alteration being overprinted by a secondary mineralogy. The intense hydrothermal alteration at both sites shows significant differences in the secondary mineralogy. At Roman Ruins, the upper 25 m of hydrothermally altered rocks are characterized by a rapid change from secondary cristobalite to quartz, implying a high temperature gradient. From 10 to 120 mbsf the clay mineralogy is dominated by illite and chlorite. The chlorite formation temperature calculated from oxygen isotope data lies at 250° C in 116 mbsf which is similar to the present fluid outflow temperatures of 240-250° C (Douville et al., 1999, Geochim. Cosmochim. Acta, 63, 627-643). Drilling in the Snowcap field recovered evidence for several stages of hydrothermal alteration. Between 50 and 150 mbsf, cristobalite and chlorite are the most abundant alteration minerals while hydrothermal pyrophyllite becomes abundant in some places At 67 mbsf, the isotopic composition of pyrophyllite gives a temperature for ist formation at 260° C whereas at 77 and 116 mbsf the pyrophyllite displays the highest temperatures of formation (>300° C). These temperatures are close to the maximum measured borehole temperatures of 313° C. The appearance of assemblages of chlorite, chlorite-vermiculite, chlorite-vermiculite-smectite and illite-smectite as well as the local development of corrensite below 150 mbsf suggests that the alteration at Snowcap may be more complex than that beneath Roman Ruins. Detailed geochemical studies of the authigenic clay mineral phases will provide further insights into the

  20. Polymorphisms of Tumor Necrosis Factor Alpha in Moroccan Patients with Gastric Pathology: New Single-Nucleotide Polymorphisms in TNF-α−193 (G/A

    Directory of Open Access Journals (Sweden)

    A. Essadik

    2015-01-01

    Full Text Available Polymorphisms in tumor necrosis factor alpha (TNF-α gene are emerging as key determinants of gastric diseases. The TNF-α−308 (G/A and TNF-α−238 (G/A single-nucleotide polymorphisms SNPs are the most extensively studied. However, all these studies are conducted in Caucasian and Asian populations. Thus, for the first time in Africa, we sought to investigate whether polymorphisms in TNF-α gene were associated with the development of gastric pathology in Morocco. Two SNPs located in the promoter region (positions −308 and −238 in TNF-α gene were genotyped in 244 individuals (170 patients and 74 healthy controls. Odds ratios (ORs and 95% confidence intervals (CI were estimated using logistic regression analysis. The TNF-α−238 (G/A genotype was significantly associated with a high risk of gastritis and gastric cancer (GC (P=0.001 and P=0.002, resp.. Furthermore, a new polymorphism located in the promoter region at position −193 in TNF-α gene was identified. The distribution of this SNP was markedly different in patients suffering from ulcers. The association between TNF-α−193 (G/A genotype and high risk of ulcer was significant (P=0.03. These results suggest that the TNF-α−193 (G/A allele has a protective function against gastric cancer by developing ulcer.

  1. The effect of acute Lithium and AMI-193, a new 5HT2 antagonist, on Apomorphine-induced pecking in pigeon

    Directory of Open Access Journals (Sweden)

    Bagheri T

    2002-06-01

    Full Text Available Intramascular (IM administration of apomorphine (a mixed D1/D2 dopamine receptors agonist 0.2-1.6 mg/kg induced pecking, a stereotype behavior in pigeons in a dose- dependent manner. In this study the effect of lithium (Li+, 240 mg/kg, IM and AMI-193 (a new 5-HT2 antagonist, 0.003 mg/pigeon on apomorphine-induced peking (AIP were investigated. This study showed that Li+ and AMI-193 did not induce pecking by itself but administration of each of these agents before apomorphine increased and decreased the AIP (apomor-phine 0.8 mg/kg respectively whereas concomitant use of Li+ (240 mg/kg IM and AMI-193 decreased AIP significantly. These results suggested that 5-HT2 antagonists inhibit the inhibitory effect of serotonin on the dopamine release in the raphe-striatal pathway but Li+ can modulate dopamine and serotonin function by different mechanisms and decrease this effect. As a result, it is mechanisms and decrease this effect. As a result, it is concluded serotonin can decrease the AIP through 5-HT2 receptors indirectly by decrease the dopamine release.

  2. LncRNA-UCA1 exerts oncogenic functions in non-small cell lung cancer by targeting miR-193a-3p.

    Science.gov (United States)

    Nie, Wei; Ge, Hui-juan; Yang, Xiao-qun; Sun, Xiangjie; Huang, Hai; Tao, Xia; Chen, Wan-sheng; Li, Bing

    2016-02-01

    Recently, the long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) has been identified as an oncogenic gene in multiple human tumor entitles, and dysregulation of UCA1 was tightly linked to carcinogenesis and cancer progression. However, whether the aberrant expression of UCA1 in non-small cell lung cancer (NSCLC) is associated with malignancy, metastasis or prognosis has not been characterized. In this study, we found that UCA1 was upregulated in NSCLC tissues. Higher expression of UCA1 led to a significantly poorer survival time, and multivariate analysis revealed that UCA1 was an independent risk factor of prognosis. UCA1 overexpression enhanced, whereas UCA1 silencing impaired the proliferation and colony formation of NSCLC cells. Moreover, mechanistic investigations showed that UCA1 upregulated the expression of miR-193a-3p target gene ERBB4 through competitively 'spongeing' miR-193a-3p. Overall, we concluded that UCA1 functions as an oncogene in NSCLC, acting mechanistically by upregulating ERBB4 in part through 'spongeing' miR-193a-3p.

  3. Strangeness production in Ni+Ni collisions at 1.93 AGeV; Production d'etrangete dans les collisions Ni+Ni a 1.93 AGeV

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, X

    2004-12-15

    This work deals with the production of strange particles in Ni + Ni collisions at 1.93 A GeV detected with the Fopi (four pi) detector at the heavy ion synchrotron SIS (GSI - Germany). We have limited our investigation to the study of {lambda} and {xi} hyperons. The first chapter presents the models used to describe ultra-relativistic heavy ions collisions. In the second chapter we present the main experimental results concerning the production and transport of strange particles in an energy domain ranging from SIS to RHIC (relativistic heavy ion collider) energies. The third chapter is dedicated to the specificities of the Fopi detector. The fourth chapter deals with the production of {lambda} particles in Ni + Ni collisions. An analysis method based on neuron network has been used in parallel with a more classical method. The production rate and temperature of {lambda} have been deduced from both methods. The neuron network method gives a statistical gain and allows a better identification of particles with low transverse impulses. The fifth chapter is dedicated to the detection of the doubly strange {xi}{sup -} particle. A detailed study about the stability of the signal is presented. In the last chapter all our experimental results are confronted with theoretical predictions. The UrQMD model that uses a hard equation of state, can simulate satisfactorily the production rates of {lambda} and K{sup +} as well as their dependency on collision centrality despite the fact that this model does not use a potential linked to the medium density. The comparison between experimental results and predictions given by the IQMD model (that is based on a soft equation of state) is better when the version of the model that does not take into account the effects of the media is used. We see that the choices for the nuclear matter compressibility, for the particles involved in Kaon and {lambda} creation process, or for the interaction potential with dense medium, appear to be

  4. Characteristics and prognostic analysis of 193 patients with special type of lung adenocarcinoma%193例特殊类型肺腺癌的临床特征及预后分析*

    Institute of Scientific and Technical Information of China (English)

    刘薇; 张翠翠; 李凯

    2013-01-01

    Objective: This work aimed to investigate the negative prognostic factors of bronchioloalveolar carcinoma (BAC) and adenocarcinoma with BAC characteristics, based on the 2004 pathological classification by the World Health Organization (WHO), which were further verified with the new pathological classification of lung adenocarcinoma (WHO 2011), to identify crucial factors that determine the prognosis of BAC and adenocarcinoma with BAC features, and to prove the coherence of the two pathological classi-fications in assessing clinical prognosis. Methods: Upon pathological diagnosis, some of the 193 cases of BAC or adenocarcinoma with BAC features were categorized into adenocarcinoma in situ (AIS) or minimally invasive adenocarcinoma (MIA), based on the 2011 WHO classification. Gender, age, tumor size, familial cancer history, smoking history, TNM stage, symptoms, duration of symp-toms, and the choice of treatment were recorded and analyzed for prognosis. The survival rate was calculated by Kaplan-Meier method. Log-rank test was introduced to compare the survival rate. Univariate and multivariate factors for the survival rate were analyzed by Cox proportional hazards regression model. Results:The overall 1-, 3-and 5-year survival rates were 84.3%, 60.6%, and 45.6%, respec-tively. Cox univariate analysis revealed that the tumor size, symptoms, TNM stage, pathological outcomes, and the choice of treatment were all prognostic factors. Cox multivariate analysis revealed that TNM stage was an independent prognostic factor for patients with BAC. Data from patients with AIS and MIA revealed better survival. Conclusion:The overall survival rate of BAC and adenocarcino-ma with BAC features are superior to that of other non-small cell lung cancer (NSCLC). The clinical symptoms are non-specific com-pared with other types of NSCLC. Clinical stage at diagnosis is a key prognostic factor, such that early correct diagnosis significantly improves survival. The new classification

  5. Effect of gamma-glutamyl kinase gene knock-out on metabolism in L-arginine-producing strain Corynebacterium crenatum 8-193%γ-谷氨酰激酶基因敲除对产L-精氨酸钝齿棒杆菌8-193生理代谢的影响

    Institute of Scientific and Technical Information of China (English)

    李小曼; 赵智; 张英姿; 王宇; 丁久元

    2011-01-01

    [目的]为了阻断L-精氨酸合成的前体物L-谷氨酸的分支代谢途径,增加L-精氨酸合成的代谢流,构建钝齿棒杆菌8-193(Corynebacterium crenatum 8-193)γ-谷氨酰激酶(EC:2.7.2.11,γ-glutamyl kinase)基因proB敲除的菌株,并研究proB基因敲除对菌株生理特性的影响.[方法]运用PCR技术分别扩增proB基因的上游和下游序列,构建带有内部缺失的proB基因的敲除载体.经过两次同源重组,敲除C.crenatum 8-193的proB基因,构建菌株8-193-ΔproB,并用带有proB基因的表达载体对8-193-ΔproB进行互补验证.通过摇瓶发酵研究8-193-ΔproB的生理特性.[结果]PCR验证、γ-谷氨酰激酶酶活测定和营养缺陷型鉴定表明,获得了proB基因缺陷的菌株.摇瓶发酵结果表明,与出发菌株相比,8-193-ΔproB生物量降低9.6%,L-精氨酸产量提高13.6%.副产物中谷氨酸族和天冬氨酸族氨基酸含量升高;α-酮戊二酸、磷酸烯醇式丙酮酸和琥珀酸含量降低.proB基因敲除后,菌株的磷酸烯醇式丙酮酸羧化酶和丙酮酸羧化酶活性提高.[结论]对谷氨酸分支代谢途径的阻断可以改善8-193菌株的葡萄糖利用和精氨酸合成能力.%[Objective] In order to optimize precursor supply for L-arginine biosynthesis, we constructed a Corynebacterium crenatum 8-193 mutant with gamma-glutamyl kinase gene (proB) in-frame deletion. The effects of proB knock-out on physiological characteristics of the mutant were investigated. [ Methods ] The upstream and downstream fragments of proB were cloned from C. Crenatum 8-193 chromosome and ligated to integration vector. The mutant C. Crenatum 8-193-△proB was obtained by homologous recombination. The mutant phenotype can be reversed by complementation with proB gene from the expression vector. The physiological characteristics of the mutant were investigated by measurement of the activities of phosphoenolpyruvate carboxylase ( PEPCx) and pyruvate carboxylase (PYC). [Results

  6. Nuclear stopping from 0.09A GeV to 1.93A GeV and its correlation to flow

    CERN Document Server

    Reisdorf, W; Gobbi, A; Hartmann, O N; Herrmann, N; Hildenbrand, K D; Kim, Y J; Kirejczyk, M; Koczón, P; Kress, T; Leifels, Y; Schüttauf, A; Tyminski, Z; Xiao, Z G; Alard, J P; Barret, V; Basrak, Z; Bastid, N; Benabderrahmane, M L; Caplar, R; Crochet, Philippe; Dupieux, P; Dzelalija, M; Fodor, Z; Grishkin, Y; Hong, B; Kecskeméti, J; Korolija, M; Kotte, R; Lebedev, A; López, X; Merschmeyer, M; Mösner, J; Neubert, W; Pelte, D; Petrovici, M; Rami, F; De, B; Schauenburg; Seres, Z; Sikora, B; Sim, K S; Simion, V; Siwek-Wilczynska, K; Smolyankin, V T; Stockmeier, M R; Stoicea, G; Wagner, P; Wisniewski, K; Wohlfarth, D; Yushmanov, I E; Zhilin, A

    2004-01-01

    We present a complete systematics (excitation functions and system-size dependences) of global stopping and sideflow for heavy ion reactions in the energy range between 0.09A GeV and 1.93A GeV. For the heaviest system, Au+Au, we observe a plateau of maximal stopping extending from about 0.2A to 0.8A GeV with a fast drop on both sides. The degree of stopping, which is shown to remain significantly below the expectations of a full stopping scenario, is found to be highly correlated to the amount of sideflow.

  7. INFRACŢIUNI CONTRA PATRIMONIULUI, SĂVÂRŞITE ÎN LIPSA UNUI SCOP SPECIAL (art.193, 197 şi 199 CP RM: ASPECTE TEORETICE ŞI PRACTICE

    Directory of Open Access Journals (Sweden)

    Sergiu BRÎNZA

    2016-03-01

    Full Text Available Prezentul articol este dedicat analizei juridico-penale a infracţiunilor contra patrimoniului, săvârşite în lipsa unui scop special. Acestea sunt prevăzute la art.193, 197 şi 199 CP RM. Sunt examinate elementele constitutive (obiectul, latura obiectivă, latura subiectivă şi subiectul, precum şi elementele circumstanţiale agravante ale infracţiunilor în cauză. Sunt propuse criterii de delimitare a infracţiunilor specificate la art.193, 197 şi 199 CP RM de faptele conexe de factură penală sau nepenală. Regulile de calificare a faptelor conform acestor articole, precum şi procedeele de interpretare a art.193, 197 şi 199 CP RM, urmăresc scopul eficientizării aplicării răspunderii pentru faptele infracţionale corespunzătoare. OFFENCES AGAINST PATRIMONY, COMMITED IN THE ABSENCE OF A SPECIAL PURPOSE (art.193, 197 and 199 PC RM: THEORETICAL AND PRACTICAL ASPECTSThis article is dedicated to the legal-penal analysis of the offences against patrimony, committed in the absence of a special purpose. The offences mentioned above are included in art.193, 197 and 199 PC RM; there are examined the constituents (the object, objective side, subjective side and the subject, as well as the circumstantial aggravating elements of the offences in question. There are also proposed delimitation criteria of the offences specified at art.193, 197 and 199 PC RM from the ancillary penal or non-penal acts. The rules of qualification of the acts under these articles, including the methods of interpretation of art.193, 197 and 199 PC RM, aim to streamline the application of penal liability for the appropriate criminal acts. 

  8. Studies of nitride- and oxide-based materials as absorptive shifters for embedded attenuated phase-shifting mask in 193 nm

    Science.gov (United States)

    Lin, Cheng-ming; Chang, Keh-wen; Lee, Ming-der; Loong, Wen-An

    1999-07-01

    Abstract-Five materials which are PdSixOy, CrAlxOy, SiNx, TiSixNy, and TiSixOyNz as absorptive shifters for attenuated phase-shifting mask in 193 nm wavelength lithography are presented. PdSixOy films were deposited by dual e-gun evaporation. CrAlxOy, TiSixNy and TiSixOyNz films were formed by plasma sputtering and SiNx films were formed with LPCVD. All of these materials are shown to be capable of achieving 4 percent - 15 percent transmittance in 193 nm with thickness that produce a 180 degrees phase shift. Under BCl3:Cl2 equals 14:70 sccm; chamber pressure 5 mtorr and RF power 1900W, the dry etching selectivity of TiSixNy over DQN positive resist and fused silica, were found to be 2:1 and 4,8:1 respectively. An embedded layer TiSixNy with 0.5 micrometers line/space was successfully patterned.

  9. Structure and magnetostrictive properties of melt-spun Pr(Fe{sub 0.4}Co{sub 0.6}){sub 1.93} alloys

    Energy Technology Data Exchange (ETDEWEB)

    Liu, J.J. [State Key Laboratory Base of Novel Functional Materials and Preparation Science, Faculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211 (China)], E-mail: liujinjun1@nbu.edu.cn; Liu, X.C. [State Key Laboratory Base of Novel Functional Materials and Preparation Science, Faculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211 (China); Zhang, W.S. [Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Si, P.Z. [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310018 (China)

    2009-12-15

    Pr(Fe{sub 0.4}Co{sub 0.6}){sub 1.93} ribbons were prepared by a melt-spinning method. Their structure and magnetic properties are investigated as functions of wheel speed and annealing temperature. The as-spun ribbon consists of a Pr(Fe, Co){sub 2} cubic Laves phase and an amorphous phase at a wheel speed of v{>=}35 m/s, while the non-cubic phases of PuNi{sub 3}-type and rare earth appear when the speed lower than 30 m/s. A single Pr(Fe, Co){sub 2} phase with MgCu{sub 2}-type structure has been synthesized by the process for the wheel speed of v{>=}35 m/s and subsequent annealing at 500 deg. C for 30 min. The epoxy/Pr(Fe{sub 0.4}Co{sub 0.6}){sub 1.93} composite has been produced by a cold isostatic pressing technique, and the magnetic properties have been investigated. The composite rod sample possesses good magnetostrictive properties, i.e., a large magnetostriction ({lambda}{sub a}={lambda}{sub parallell}ambda{sub perpendicular}) of 710 ppm at 800 kA/m and a dynamic coefficient d{sub 33} of 0.67 nm/A at 100 kA/m, and is of practical value.

  10. Chemonuclear studies for identification for new production routes for the therapeutically useful radionuclides {sup 140}Nd, {sup 192}Ir, {sup 191}Pt, {sup 193m}Pt, und {sup 195m}Pt; Kernchemische Studien zur Entwicklung neuerer Produktionsverfahren fuer die therapierelevanten Radionuklide {sup 140}Nd, {sup 192}Ir, {sup 191}Pt, {sup 193m}Pt, und {sup 195m}Pt

    Energy Technology Data Exchange (ETDEWEB)

    Hilgers, K.

    2005-12-15

    New production routes for the therapeutically useful radionuclides {sup 140}Nd, {sup 192}Ir, {sup 191}Pt, {sup 193m}Pt and {sup 195m}Pt were investigated. Cross section data were measured using the stacked-foil technique and compared with theoretical calculations. A production method for the platinum nuclides was developed. The {sup 141}Pr(p, 2n){sup 140}Nd and {sup nat}Ce({sup 3}He, xn){sup 140}Nd reactions were investigated for production of {sup 140}Nd. Cross section data of nuclear reactions leading to the side products {sup 141}Nd, {sup 139}Nd and {sup 139}Ce could also be achieved. The experimental data were compared with theoretical calculations using the code ALICE-IPPE. A comparison of the calculated thick target yields showed that the {sup 141}Pr(p, 2n){sup 140}Nd reaction gives a higher yield. The {sup 192}Os(p, n){sup 192}Ir reaction was examined in the context of the production of {sup 192}Ir. Cross section data were determined and compared with theoretical calculations using the codes ALICE-IPPE and EMPIRE II. The yield of this reaction was compared with the yield of the reactor production of this nuclide. The reactor production seems to be more suitable because of a higher purity and yield. Cross section data were measured for the {sup 192}Os({alpha}, n){sup 195m}Pt, {sup 192}Os({alpha}, 3n){sup 193m}Pt and {sup 192}Os({sup 3}He, 4n){sup 191}Pt reactions. The activity of {sup 193m}Pt and {sup 195m}Pt was determined by X-ray spectroscopy after a chemical separation procedure. The ALICE-IPPE code was found to be inappropriate to reproduce the experimental values. The calculated yields were compared with the yields of other reactions, especially the reactor production of {sup 195m}Pt. The yield of the {sup 192}Os({alpha}, n){sup 195m}Pt reaction is lower compared to the yield of the reactor production, but offers lower target costs and higher specific activity. A production method for {sup 193m}Pt and {sup 195m}Pt was developed. Batch yields of 0.9 MBq

  11. 中材国际(天津)签1.93亿欧元水泥生产线总承包合同

    Institute of Scientific and Technical Information of China (English)

    文津

    2014-01-01

    <正>中材国际天津公司与阿尔及利亚SPA CILAS(Ciment LAFARGE SOUAKRI)水泥公司签署了阿尔及利亚BISKRA日产5000吨熟料水泥生产线总承包合同。合同金额合计约为1.93亿欧元。BISKRA项目是一条全新的水泥生产线,范围从石灰石破碎到水泥包装发运,包括设计、供货、土建、安装、培训和调试,合同采用EPC模式。项目由阿尔

  12. Simulation of research loop LOBI-MOD2 with RELAP5/MOD3.3 code for LOBI thermo hydraulic test A1-93

    Energy Technology Data Exchange (ETDEWEB)

    Pesaran, Farshad; Barati, Ramin [Islamic Azad Univ., Shiraz (Iran, Islamic Republic of). Dept. of Electrical Engineering

    2016-06-15

    RELAP5/MOD3.3 is one of the used computer codes for the simulation of event thermal-hydraulics of nuclear power plants. The LOBI test facility is a full-power high-pressure integral system test facility, representing an approximately 1: 700 scale model of a 4-loop, 1300 MWe PWR. A new simulation of the small break LOCA test A1-93 has been carried out in a LOBI/Mod2 facility for reaching good agreement and to evaluate the performance of the RELAP5/MOD3.3 code. Good agreement was obtained in general between the code predictions and the experimental data in transient state.

  13. Production of non-photonic electrons in U+U collisions at √sNN = 193 GeV at the STAR experiment

    Directory of Open Access Journals (Sweden)

    Gajdosova Katarina

    2016-01-01

    Measurements of NPE RAA in Au+Au collisions at √sNN = 200 GeV reveal that NPE production is strongly suppressed. In year 2012 STAR collected data from U+U collisions at √sNN = 193 GeV. In most central collisions higher energy density can be achieved in comparison to collisions of gold nuclei. In this proceedings the preliminary results on NPE in 0-5% most central U+U collisions at a transverse momentum range 1.2 < pT < 6 GeV/c are presented. The nuclear modification factor in U+U collisions is compared to that in Au+Au collisions and theoretical models.

  14. Spin-orbit relaxation rates of Bi(6p(3)) 2D(3/2) following photolysis of Bi(CH3)3 at lambda = 193 nm

    Science.gov (United States)

    Holloway, J. S.; Koffend, J. B.; Heidner, R. F., III

    1989-07-01

    Rate coefficients for the collisional relaxation of the first excited spin-orbit state of Bismuth (6p3, 2D3/2) have been measured at 295 K for argon, carbon dioxide, sulfur hexaflouride, hydrogen, deuterium, hydrogen flouride. The excited Bi atoms were prepared by excimer laser photolysis of trimethyl bismuth (TMB) at 193 nm and monitored directly in emission. The rate coefficient for quenching by the precursor TMB and a lower limit for removal by CH3 photofragments have also been established. Where applicable, our results are compared with the earlier work of Bevan and Husain and of Trainor. The suitability of long-range interaction models is discussed for those cases where isotopic substitution leads to markedly different quenching rates.

  15. Electron Photodetachment from Aqueous Anions. I. Quantum Yields for Generation of Hydrated Electron by 193 and 248 nm Laser Photoexcitation of Miscellaneous Inorganic Anions

    CERN Document Server

    Sauer, M C; Shkrob, I A; Sauer, Myran C.; Shkrob, Ilya A.

    2004-01-01

    Time resolved transient absorption spectroscopy has been used to determine quantum yields for electron photodetachment in 193 nm and (where possible) 248 nm laser excitation of miscellaneous aqueous anions, including hexacyanoferrate(II), sulfate, sulfite, halide anions (Cl-, Br-, and I-), pseudohalide anions (OH-, HS-, CNS-), and several common inorganic anions for which no quantum yields have been reported heretofore: SO3=, NO2-, NO3-, ClO3- and ClO4-. Molar extinction coefficients for these anions and photoproducts of electron detachment from these anions at the excitation wavelengths were also determined. These results are discussed in the context of recent ultrafast kinetic studies and compared with the previous data obtained by product analyses. We suggest using electron photodetachment from the aqueous halide and pseudohalide anions as actinometric standard for time-resolved studies of aqueous photosystems in the UV.

  16. Dynamics of N-OH bond dissociation in cyclopentanone and cyclohexanone oxime at 193 nm: laser-induced fluorescence detection of nascent OH (v'', J'').

    Science.gov (United States)

    Kawade, Monali N; Saha, Ankur; Upadhyaya, Hari P; Kumar, Awadhesh; Naik, Prakash D

    2010-12-01

    Cyclohexanone oxime (CHO) and cyclopentanone oxime (CPO) in the vapor phase undergo N-OH bond scission upon excitation at 193 nm to produce OH, which was detected state selectively employing laser-induced fluorescence. The measured energy distribution between fragments for both oximes suggests that in CHO the OH produced is mostly vibrationally cold, with moderate rotational excitation, whereas in CPO the OH fragment is also formed in v'' = 1 (~2%). The rotational population of OH (v'' = 0, J'') from CHO is characterized by a rotational temperature of 1440 ± 80 K, whereas the rotational populations of OH (v'' = 0, J'') and OH (v'' = 1, J'') from CPO are characterized by temperatures of 1360 ± 90 K and 930 ± 170 K, respectively. A high fraction of the available energy is partitioned to the relative translation of the fragments with f(T) values of 0.25 and 0.22 for CHO and CPO, respectively. In the case of CHO, the Λ-doublet states of the nascent OH radical are populated almost equally in lower rotational quantum levels N'', with a preference for Π(+) (A') states for higher N''. However, there is no preference for either of the two spin orbit states Π(3/2) and Π(1/2) of OH. The nascent OH product in CPO is equally distributed in both Λ-doublet states of Π(+) (A') and Π(-) (A'') for all N'', but has a preference for the Π(3/2) spin orbit state. Experimental work in combination with theoretical calculations suggests that both CHO and CPO molecules at 193 nm are excited to the S(2) state, which undergoes nonradiative relaxation to the T(2) state. Subsequently, molecules undergo the N-OH bond dissociation from the T(2) state with an exit barrier to produce OH (v'', J'').

  17. Oxalyl chloride, ClC(O)C(O)Cl: UV/vis spectrum and Cl atom photolysis quantum yields at 193, 248, and 351 nm.

    Science.gov (United States)

    Ghosh, Buddhadeb; Papanastasiou, Dimitrios K; Burkholder, James B

    2012-10-28

    Oxalyl chloride, (ClCO)(2), has been used as a Cl atom photolytic precursor in numerous laboratory kinetic and photochemical studies. In this study, the UV/vis absorption spectrum of (ClCO)(2) and the Cl atom quantum yields in its photolysis at 193, 248, and 351 nm are reported. The UV∕vis spectrum was measured between 200 and 450 nm at 296 K using diode array spectroscopy in conjunction with an absolute cross section obtained at 213.9 nm. Our results are in agreement with the spectrum reported by Baklanov and Krasnoperov [J. Phys. Chem. A 105, 97-103 (2001)], which was obtained at 11 discrete wavelengths between 193.3 and 390 nm. Cl atom quantum yields, Φ(λ), were measured using pulsed laser photolysis coupled with time resolved atomic resonance fluorescence detection of Cl. The UV photolysis of (ClCO)(2) has been shown in previous studies to occur via an impulsive three-body dissociation mechanism, (COCl)(2) + hv → ClCO* + Cl + CO (2), where the excited ClCO radical, ClCO*, either dissociates or stabilizes ClCO* → Cl + CO (3a), → ClCO (3b). ClCO is thermally unstable at the temperatures (253-298 K) and total pressures (13-128 Torr) used in our experiments ClCO + M → Cl + CO + M (4) leading to the formation of a secondary Cl atom that was resolvable in the Cl atom temporal profiles obtained in the 248 and 351 nm photolysis of (ClCO)(2). Φ(193 nm) was found to be 2.07 ± 0.37 independent of bath gas pressure (25.8-105.7 Torr, N(2)), i.e., the branching ratio for channel 2a or the direct formation of 2Cl + 2CO in the photolysis of (ClCO)(2) is >0.95. At 248 nm, the branching ratio for channel 2a was determined to be 0.79 ± 0.15, while the total Cl atom yield, i.e., following the completion of reaction (4), was found to be 1.98 ± 0.26 independent of bath gas pressure (15-70 Torr, N(2)). Φ(351 nm) was found to be pressure dependent between 7.8 and 122.4 Torr (He, N(2)). The low-pressure limit of the total Cl atom quantum yield, Φ(0)(351 nm), was 2

  18. Kinetic and internal energy distributions via velocity-aligned Doppler spectroscopy: The 193 nm photodissociation of H/sub 2/S and HBr

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Z.; Koplitz, B.; Wittig, C.

    1987-07-15

    We report center-of-mass kinetic energy distributions for the 193 nm photodissociation of H/sub 2/S and HBr using the method of velocity--aligned Doppler spectroscopy. Nascent H atoms are detected by sequential two-photon photoionization via Lyman-..cap alpha.. (121.6 nm + 364.7 nm), and internal SH(X /sup 2/Pi) and Br excitations are observed directly in the H-atom kinetic energy distributions. The kinetic energy resolution is much better than in ''conventional'' sub-Doppler resolution spectroscopy and results from detecting spatially selected species whose velocities are aligned with the wave vector of the probe radiation, k/sub probe/, thereby providing a kinetic energy distribution for a specific laboratory direction. This improved resolution is achieved in the present experiments by using pulsed, collimated, and overlapped photolysis and probe beams, but the vital aspect of the technique involves increasing the delay between the two lasers in order to discriminate against species having velocity components perpendicular to k/sub probe/.

  19. Neutron scattering study of spin ordering and stripe pinning in superconducting La1.93Sr0.07CuO4

    Science.gov (United States)

    Jacobsen, H.; Zaliznyak, I. A.; Savici, A. T.; Winn, B. L.; Chang, S.; Hücker, M.; Gu, G. D.; Tranquada, J. M.

    2015-11-01

    The relationships among charge order, spin fluctuations, and superconductivity in underdoped cuprates remain controversial. We use neutron scattering techniques to study these phenomena in La1.93Sr0.07CuO4 , a superconductor with a transition temperature of Tc=20 K. At T ≪Tc we find incommensurate spin fluctuations with a quasielastic energy spectrum and no sign of a gap within the energy range from 0.2 to 15 meV. A weak elastic magnetic component grows below ˜10 K, consistent with results from local probes. Regarding the atomic lattice, we have discovered unexpectedly strong fluctuations of the CuO6 octahedra about Cu-O bonds, which are associated with inequivalent O sites within the CuO2 planes. Furthermore, we observed a weak elastic (3 3 ¯0 ) superlattice peak that implies a reduced lattice symmetry. The presence of inequivalent O sites rationalizes various pieces of evidence for charge stripe order in underdoped La2 -xSrxCuO4 . The coexistence of superconductivity with quasistatic spin-stripe order suggests the presence of intertwined orders; however, the rotation of the stripe orientation away from the Cu-O bonds might be connected with evidence for a finite gap at the nodal points of the superconducting gap function.

  20. The Environmental Protection Agency`s proposed regulation of low level radioactive waste (40 CFR Part 193): A Department of Energy overview

    Energy Technology Data Exchange (ETDEWEB)

    Frangos, T.G. [Dept. of Energy, Washington, DC (United States)

    1989-11-01

    The Department of Energy (DOE) manages one of the world`s largest programs for storage, treatment, and disposal of low-level radioactive wastes. This system with facilities located at sites across the nation has evolved over some forty years in response to changing needs, technologies, and increasing public awareness and concerns for environmental protection. The DOE has operated in a self regulatory mode in most aspects of its low-level waste (LLW) programs. It has been DOE`s policy and practice to provide at least the same level of safety and protection for the public, DOE and contractor employees, and the general environment, as that required by the Nuclear Regulatory Commission for commercial operations. DOE`s policies have been implemented through a management system that historically has been highly decentralized so as to be responsive to the needs of DOE sites which generate a wide variety of wastes at some 25 locations. In addition to concerns with the LLW that it manages, DOE has an interest in the US Environmental Protection Agency`s (EPA) promulgation of 40 CFR Part 193 because of its responsibilities under the Low Level Radioactive Waste Policy Amendments Act (LLRWPAA) to manage certain classes of waste and to assist and encourage the development of interstate compact-managed regional low-level waste disposal sites.

  1. Production of non-photonic electrons in U+U collisions at √sNN = 193 GeV at the STAR experiment

    Science.gov (United States)

    Gajdosova, Katarina

    2016-11-01

    Heavy quarks are suitable probes to study the properties of Quark-Gluon Plasma (QGP), a strongly interacting medium, which can be created in ultrarelativistic heavy-ion collisions at the Relativistic Heavy Ion Collider (RHIC). Non-photonic electrons (NPE) that originate from semileptonic decays of D and B mesons can serve as a good proxy for heavy flavor quarks. Nuclear modification factor RAA of NPE is measured in heavy-ion collisions, which is sensitive to the effect of QGP on heavy quarks. Measurements of NPE RAA in Au+Au collisions at √sNN = 200 GeV reveal that NPE production is strongly suppressed. In year 2012 STAR collected data from U+U collisions at √sNN = 193 GeV. In most central collisions higher energy density can be achieved in comparison to collisions of gold nuclei. In this proceedings the preliminary results on NPE in 0-5% most central U+U collisions at a transverse momentum range 1.2 < pT < 6 GeV/c are presented. The nuclear modification factor in U+U collisions is compared to that in Au+Au collisions and theoretical models.

  2. Υ production in U + U collisions at √{sN N}=193 GeV measured with the STAR experiment

    Science.gov (United States)

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Anderson, D. M.; Aoyama, R.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Ashraf, M. U.; Attri, A.; Averichev, G. S.; Bai, X.; Bairathi, V.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chatterjee, A.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Esumi, S.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A. I.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Horvat, S.; Huang, H. Z.; Huang, B.; Huang, T.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jentsch, A.; Jia, J.; Jiang, K.; Jowzaee, S.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Kochenda, L.; Koetke, D. D.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kumar, L.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, Y.; Li, C.; Li, X.; Li, W.; Li, X.; Lin, T.; Lisa, M. A.; Liu, F.; Liu, Y.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Luo, S.; Ma, G. L.; Ma, R.; Ma, L.; Ma, Y. G.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Matis, H. S.; McDonald, D.; McKinzie, S.; Meehan, K.; Mei, J. C.; Miller, Z. W.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Niida, T.; Nogach, L. V.; Nonaka, T.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V. A.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Pile, P.; Pluta, J.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Pruthi, N. K.; Przybycien, M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Ray, R. L.; Reed, R.; Rehbein, M. J.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roth, J. D.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, A.; Sharma, B.; Shen, W. Q.; Shi, Z.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Singha, S.; Skoby, M. J.; Smirnov, D.; Smirnov, N.; Solyst, W.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sugiura, T.; Sumbera, M.; Summa, B.; Sun, Y.; Sun, Z.; Sun, X. M.; Surrow, B.; Svirida, D. N.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thäder, J.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Todoroki, T.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, J. S.; Wang, F.; Wang, Y.; Wang, Y.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y.; Xiao, Z. G.; Xie, G.; Xie, W.; Xin, K.; Xu, Z.; Xu, H.; Xu, N.; Xu, J.; Xu, Y. F.; Xu, Q. H.; Yang, Y.; Yang, Y.; Yang, S.; Yang, Q.; Yang, Y.; Yang, C.; Ye, Z.; Ye, Z.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J. B.; Zhang, Y.; Zhang, S.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

    2016-12-01

    We present a measurement of the inclusive production of Υ mesons in U+U collisions at √{sN N}=193 GeV at midrapidity (|y |<1 ). Previous studies in central Au+Au collisions at √{sN N}=200 GeV show a suppression of Υ (1S+2S+3S) production relative to expectations from the Υ yield in p+p collisions scaled by the number of binary nucleon-nucleon collisions (Ncoll), with an indication that the Υ (1S) state is also suppressed. The present measurement extends the number of participant nucleons in the collision (Npart) by 20% compared to Au+Au collisions, and allows us to study a system with higher energy density. We observe a suppression in both the Υ (1 S +2 S +3 S ) and Υ (1 S ) yields in central U+U data, which consolidates and extends the previously observed suppression trend in Au+Au collisions.

  3. 基于生态事件的企业社会回应研究——以蓬莱19-3油田溢油案为例%Research on Corporate Social Responsiveness Based on Ecological Events: A Case Study of Penglai 19-3 Field Incident in Bohai Bay

    Institute of Scientific and Technical Information of China (English)

    胡建军; 金炜东; 董大勇

    2013-01-01

    企业在生态事件中有效回应社会压力对企业、社会和生态环境的可持续发展具有重要意义.基于企业社会回应的理论与方法,对蓬莱19-3油田溢油事件中康菲公司的企业社会回应进行了深入分析,研究发现企业的社会责任担当、生态环保的立法执法环境、政府处置生态环境事故的效率、社会公众的生态环保意识是企业社会回应有效性的关键影响因素,并从企业内部管理和外部环境建设两方面对提高生态事件中企业社会回应有效性提出建议.%It has important significance for the sustainable development of enterprises, social and ecological environment that Enterprises effectively respond to social pressure in the ecological incident. Based on the theories and methods of corporate social responsiveness, this paper take in-depth analysis of Conoco Phillips China's corporate social responsiveness in Penglai 19-3 field incident in Bohai Bay. The result of our exploration indicates that, corporate social responsibility, legislation and law enforcement environment, the efficiency of government, public awareness of ecological and environmental protection are four decisive factors of corporate social responsiveness in ecological incident. From tow aspects of internal management and external environment construction, this article puts forward suggestions about related policies.

  4. Search and analysis of superdeformed and oblate states in {sup 193}Pb nucleus with the EUROGAM II multidetector array; Recherche et analyse des etats superdeformes et aplatis dans le noyau {sup 193}Pb a l'aide du multidetecteur EUROGAM II

    Energy Technology Data Exchange (ETDEWEB)

    Ducroux, L. [Lyon-1 Univ., 69 - Villeurbanne (France). Inst. de Physique Nucleaire]|[Universite Claude Bernard, 69 - Lyon (France)

    1997-01-09

    This work is devoted to the search and analysis of superdeformed and oblate states in {sup 193}Pb nucleus. High spin states of this isotope, populated via fusion-evaporation reaction {sup 168}Er ({sup 30}Si, 5n) {sup 193}Pb, have been studied with the EUROGAM II {gamma} multidetector array located near the VIVITRON accelerator in Strasbourg. New sorting and analysis programs have been developed in particular related to the background treatment. Angular distribution and linear polarisation analysis allowed us to assign the {gamma} transition multipolarities. Five dipole bands, corresponding to a weakly oblate-deformed shape of the nucleus, have been observed and connected to the low-lying states. The level scheme has been considerably extended up to a spin of 61/2 {Dirac_h} and an excitation energy of about 8 MeV. These structures have been interpreted as based on a high-K two-quasi-proton excitation coupled to rotation aligned quasi-neutrons. Six superdeformed bands, corresponding to a high prolate-deformed shape of the nucleus, have been observed. These six bands have been interpreted as three pairs of signature partners based on quasineutron excitations. The extraction of the g-factor of a K=9/2 neutron superdeformed orbital has been done for the first time in lead isotopes, giving access to the magnetic properties of the extreme nuclear matter. All these results have been discussed in terms of microscopic mean field self-consistent Hartree-Fock calculations using the microscopic 'rotor + particle(s)' model. (author)

  5. Structure of the Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme and enzymatic inactivation by mutation of the heme coordinating residue His-193

    Energy Technology Data Exchange (ETDEWEB)

    Suits,M.; Jaffer, N.; Jia, Z.

    2006-01-01

    Heme oxygenases catalyze the oxidation of heme to biliverdin, CO, and free iron. For pathogenic microorganisms, heme uptake and degradation are critical mechanisms for iron acquisition that enable multiplication and survival within hosts they invade. Here we report the first crystal structure of the pathogenic Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme at 1.45 {angstrom} resolution. When compared with other heme oxygenases, ChuS has a unique fold, including structural repeats and a {beta}-sheet core. Not surprisingly, the mode of heme coordination by ChuS is also distinct, whereby heme is largely stabilized by residues from the C-terminal domain, assisted by a distant arginine from the N-terminal domain. Upon heme binding, there is no large conformational change beyond the fine tuning of a key histidine (His-193) residue. Most intriguingly, in contrast to other heme oxygenases, the propionic side chains of heme are orientated toward the protein core, exposing the {alpha}-meso carbon position where O{sub 2} is added during heme degradation. This unique orientation may facilitate presentation to an electron donor, explaining the significantly reduced concentration of ascorbic acid needed for the reaction. Based on the ChuS-heme structure, we converted the histidine residue responsible for axial coordination of the heme group to an asparagine residue (H193N), as well as converting a second histidine to an alanine residue (H73A) for comparison purposes. We employed spectral analysis and CO measurement by gas chromatography to analyze catalysis by ChuS, H193N, and H73A, demonstrating that His-193 is the key residue for the heme-degrading activity of ChuS.

  6. THE CARMA PAIRED ANTENNA CALIBRATION SYSTEM: ATMOSPHERIC PHASE CORRECTION FOR MILLIMETER WAVE INTERFEROMETRY AND ITS APPLICATION TO MAPPING THE ULTRALUMINOUS GALAXY ARP 193

    Energy Technology Data Exchange (ETDEWEB)

    Zauderer, B. Ashley; Bolatto, Alberto D.; Vogel, Stuart N.; Curley, Roger; Pound, Marc W.; Mundy, Lee G.; Teng, Stacy H.; Teuben, Peter J. [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Carpenter, John M. [California Institute of Technology, Department of Astronomy, MC 249-17, Pasadena, CA 91125 (United States); Peréz, Laura M. [National Radio Astronomy Observatory, P.O. Box 0, Socorro, NM 87801 (United States); Lamb, James W.; Woody, David P.; Leitch, Erik M.; Muchovej, Stephen J.; Volgenau, Nikolaus H. [California Institute of Technology, Owens Valley Radio Observatory, Big Pine, CA 93513 (United States); Bock, Douglas C.-J. [CSIRO Astronomy and Space Science, P.O. Box 76, Epping NSW 1710 (Australia); Carlstrom, John E.; Culverhouse, Thomas L. [Department of Astronomy and Astrophysics, University of Chicago, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Plambeck, Richard L. [Radio Astronomy Laboratory, University of California, Berkeley, 601 Campbell Hall, Berkeley, CA 94720 (United States); Marrone, Daniel P. [Department of Astronomy, Steward Observatory, University of Arizona, Tucson, AZ 85721 (United States); and others

    2016-01-15

    Phase fluctuations introduced by the atmosphere are the main limiting factor in attaining diffraction limited performance in extended interferometric arrays at millimeter and submillimeter wavelengths. We report the results of C-PACS, the Combined Array for Research in Millimeter-Wave Astronomy Paired Antenna Calibration System. We present a systematic study of several hundred test observations taken during the 2009–2010 winter observing season where we utilize CARMA's eight 3.5 m antennas to monitor an atmospheric calibrator while simultaneously acquiring science observations with 6.1 and 10.4 m antennas on baselines ranging from a few hundred meters to ∼2 km. We find that C-PACS is systematically successful at improving coherence on long baselines under a variety of atmospheric conditions. We find that the angular separation between the atmospheric calibrator and target source is the most important consideration, with consistently successful phase correction at CARMA requiring a suitable calibrator located ≲6° away from the science target. We show that cloud cover does not affect the success of C-PACS. We demonstrate C-PACS in typical use by applying it to the observations of the nearby very luminous infrared galaxy Arp 193 in {sup 12}CO(2-1) at a linear resolution of ≈70 pc (0.″12 × 0.″18), 3 times better than previously published molecular maps of this galaxy. We resolve the molecular disk rotation kinematics and the molecular gas distribution and measure the gas surface densities and masses on 90 pc scales. We find that molecular gas constitutes ∼30% of the dynamical mass in the inner 700 pc of this object with a surface density ∼10{sup 4} M{sub ⊙} pc{sup −2}; we compare these properties to those of the starburst region of NGC 253.

  7. FEM for modelling 193 nm excimer laser treatment of SiO{sub 2}/Si/Si{sub (1-x)}Ge{sub x} heterostructures on SOI substrates

    Energy Technology Data Exchange (ETDEWEB)

    Conde, J.C.; Chiussi, S.; Gontad, F.; Gonzalez, P. [Dpto. Fisica Aplicada, E.T.S.I.I. University of Vigo, Campus Universitario, Rua Maxwell s/n, 36310 Vigo (Spain); Martin, E. [Dpto. de Mecanica, Maquinas, Motores Termicos y Fluidos, E.T.S.I.I. University of Vigo, Campus Universitario, Rua Maxwell s/n, 36310 Vigo (Spain)

    2011-03-15

    Research on epitaxial crystalline silicon (c-Si) and silicon-germanium (Si{sub 1-x}Ge{sub x}) alloys growth and annealing for microelectronic purposes, such as Micro- or Nano-Electro-Mechanical Systems (MEMS or NEMS) and Silicon-On-Nothing (SON) devices is continuously in progress. Laser assisted annealing techniques using commercial ArF Excimer Laser sources are based on ultra-rapid heating and cooling cycles induced by the 193 nm pulses of 20 ns, which are absorbed in the near surface region of the heterostructures. During and after the absorption of these laser pulses, complex physical processes appear that strongly depend on sample structure and applied laser pulse energy densities. The control of the experimental parameters is therefore a key task for obtaining high quality alloys. The Finite ElementsMethod (FEM) is a powerful tool for the optimization of such treatments, because it provides the spatial and temporal temperature fields that are produced by the laser pulses. In this work, we have used a FEM commercial software, to predict the temperatures gradients induced by ArF excimer laser over a wide energy densities range, 0.1<{phi}<0.4 J/cm{sup 2}, on different SiO{sub 2}/Si/Si{sub (1-x)}Ge{sub (x)} thin films deposited on SOI substrate. These numerical results allow us to predict the threshold energies needed to reach the melting point (MP) of the Si and SiGe alloy without oxidation of the thin films system. Therefore, it is possible to optimize the conditions to achieve high quality epitaxy films. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  8. The CARMA Paired Antenna Calibration System: Atmospheric Phase Correction for Millimeter Wave Interferometry and Its Application to Mapping the Ultraluminous Galaxy Arp 193

    Science.gov (United States)

    Zauderer, B. Ashley; Bolatto, Alberto D.; Vogel, Stuart N.; Carpenter, John M.; Peréz, Laura M.; Lamb, James W.; Woody, David P.; Bock, Douglas C.-J.; Carlstrom, John E.; Culverhouse, Thomas L.; Curley, Roger; Leitch, Erik M.; Plambeck, Richard L.; Pound, Marc W.; Marrone, Daniel P.; Muchovej, Stephen J.; Mundy, Lee G.; Teng, Stacy H.; Teuben, Peter J.; Volgenau, Nikolaus H.; Wright, Melvyn C. H.; Wu, Dalton

    2016-01-01

    Phase fluctuations introduced by the atmosphere are the main limiting factor in attaining diffraction limited performance in extended interferometric arrays at millimeter and submillimeter wavelengths. We report the results of C-PACS, the Combined Array for Research in Millimeter-Wave Astronomy Paired Antenna Calibration System. We present a systematic study of several hundred test observations taken during the 2009-2010 winter observing season where we utilize CARMA's eight 3.5 m antennas to monitor an atmospheric calibrator while simultaneously acquiring science observations with 6.1 and 10.4 m antennas on baselines ranging from a few hundred meters to ˜2 km. We find that C-PACS is systematically successful at improving coherence on long baselines under a variety of atmospheric conditions. We find that the angular separation between the atmospheric calibrator and target source is the most important consideration, with consistently successful phase correction at CARMA requiring a suitable calibrator located ≲6° away from the science target. We show that cloud cover does not affect the success of C-PACS. We demonstrate C-PACS in typical use by applying it to the observations of the nearby very luminous infrared galaxy Arp 193 in 12CO(2-1) at a linear resolution of ≈70 pc (0.″12 × 0.″18), 3 times better than previously published molecular maps of this galaxy. We resolve the molecular disk rotation kinematics and the molecular gas distribution and measure the gas surface densities and masses on 90 pc scales. We find that molecular gas constitutes ˜30% of the dynamical mass in the inner 700 pc of this object with a surface density ˜104 M⊙ pc-2 we compare these properties to those of the starburst region of NGC 253.

  9. 国际标准化组织天然气技术委员会天然气上游领域分委会ISO/TC193/SC3第四次年会情况报告%The Report on the Situation of the Fourth Annual Conference Held by ISO/TC 193/SC3 Sub-Committee of Natural Gas Upper Field in Natural Gas Technical Commission of International Standardization Organization

    Institute of Scientific and Technical Information of China (English)

    罗勤; 崔建华; 何敏

    2008-01-01

    国际标准化组织天然气技术委员会天然气上游领域分委会ISO/TC193/SC3第4届年会于2008年5月6日在美国德克萨斯州休斯顿市召开,本届年会由ISO/TC193/SC3秘书处(美国石油学会API/美国国家标准学会ANSI)举办,BP美国公司承办了该次会议。来自挪威、泰国、中国、美国等4个国家的15名代表出席了会议,

  10. Oil spill information extraction combined with texture features from HJ-CCD Sensors-A case study in PL19-3 oil spill incident%辅以纹理特征的HJ-CCD海上溢油信息提取——以PL19-3溢油为例

    Institute of Scientific and Technical Information of China (English)

    李颖; 兰国新; 刘丙新

    2012-01-01

    Traditional information extraction technique of optical satellite remote sensing constitutes an important component of oil spills monitoring system, but it subjects to monitoring accuracy and ability dependence on spectral features. Based on CCD (30m spatial resolution) data from operational HJ instruments, we taking Penglai 19-3 oil spill incident was took as an example to discuss the method of combining spectrum with directional textural information to improve the accuracy of extracted information. A principal components-based algorithm first extracted all spectrum information of oil-on-water. Then a directional gradient algorithm acquired the edge distribution of oil-contaminated area. Finally, the proposal method were tested with 8 scenes of HJ-CCD data and compared with conventional method based on singe spectrum using Jefrries-Matusita separability index. The results show that the introduction of the directional texture analysis is effective to the edge detection of contaminated zone and the identification of thick-thin oil distribution, which is feasible in the oil spill monitoring based on HJ-CCD data.%鉴于依赖光谱特征的传统溢油信息提取方法面临信息提取精度低的困境,提出采用光谱特征与纹理分析结合的方法应用于溢油监测.选择位于渤海的蓬莱19-3油田溢油事故为研究对象,基于覆盖溢油事故阶段的8景30m分辨率HJ-CCD数据,在溢油目标提取过程中,引入了方向性纹理特征分析,将主成分光谱降维、方向梯度边缘检测等技术相结合,形成了基于光谱与纹理特征的溢油信息提取技术.所述方法经8组数据检验后,用类间分歧度方法进行了对比评价.结果表明:将纹理分析方法应用于溢油信息提取,类间分歧度提高到1.9999,提高了油膜影响边界和油膜厚度分区识别能力.

  11. Kinetic and internal energy distributions via velocity-aligned Doppler spectroscopy: The 193 nm photodissociation of H2S and HBr

    Science.gov (United States)

    Xu, Z.; Koplitz, B.; Wittig, C.

    1987-07-01

    We report center-of-mass kinetic energy distributions for the 193 nm photodissociation of H2S and HBr using the method of velocity-aligned Doppler spectroscopy. Nascent H atoms are detected by sequential two-photon photoionization via Lyman-α (121.6 nm + 364.7 nm), and internal SH(X 2Π) and Br excitations are observed directly in the H-atom kinetic energy distributions. The kinetic energy resolution is much better than in ``conventional'' sub-Doppler resolution spectroscopy and results from detecting spatially selected species whose velocities are aligned with the wave vector of the probe radiation, kprobe, thereby providing a kinetic energy distribution for a specific laboratory direction. This improved resolution is achieved in the present experiments by using pulsed, collimated, and overlapped photolysis and probe beams, but the vital aspect of the technique involves increasing the delay between the two lasers in order to discriminate against species having velocity components perpendicular to kprobe. In the case of HBr, we identify the Br(2P3/2) and Br(2P1/2) contributions and find that the Br(2P1/2) channel accounts for approximately 14% of the fragmentation associated with perpendicular electronic transitions. Concerning H2S, SH(X 2Π) vibrational structure is clearly evident in the H-atom kinetic energy distribution, and the SH vibrational distribution shows oscillations, with [v″=0]>[v″=1], [v″=1][v″=3], [v″=3][v″=5]. Such oscillatory behavior was predicted theoretically by Kulander. A simulation of our data places 32% of the SH in v″>0 (˜2700 cm-1, which is approximately 14% of the available energy, hν-D0), while the general features of our H2S data are in accord with the TOF study of van Veen et al. Presently, our measurements appear to be limited by the dye laser resolution (˜0.06 cm-1 at 364.7 nm), but a significant improvement of the laser bandwidth is possible using commercially available sources. The velocity-aligned Doppler

  12. Mechanisms of the pancake vortex and vortex line movement in the high Tc superconductors Bi2Sr2CaCu2O8+δ and La1.93Sr0.07CuO4+δ

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In the strict sense, it is not very clear why with magnetic field increasing, the normal-superconductive (NS) transition becomes broad for Bi2Sr2CaCu208+δ(Bi2212) while the NS transitions are almost parallel for La193Sroo7Cu04+δ(La214). In this paper, R-T relations are measured by the six-probe method. We propose a moving mechanism of the pancake vortex and vortex line for Bi2212. The theoretical curves fit the experiment data well.

  13. Influence of the Texture and Strain on the Behaviour of Ni53.6Mn27.1Ga19.3 and Ni54.2Mn29.4Ga16.4 Shape Memory Alloys

    Directory of Open Access Journals (Sweden)

    Alexandra Rudajevova

    2013-01-01

    Full Text Available Polycrystalline samples of Ni53.6Mn27.1Ga19.3 and Ni54.2Mn29.4Ga16.4 shape memory alloys were investigated using dilatometry. The longitudinal axes of the samples were perpendicular to the columnar grains. Both alloys showed positive shape memory effects. The martensitic phase transformation occurred without hysteresis in both alloys with transformation temperatures of 174°C for the Ni53.6Mn27.1Ga19.3 alloy and 253°C for the Ni54.2Mn29.4Ga16.4 alloy. The dilatation characteristics for both alloys were determined in three perpendicular directions. The strain associated with the internal stress at the interface between the two martensitic structures and the two grains affected the dilatation characteristics in the y and z directions (perpendicular to the longitudinal axis of the sample. The microstructure was determined for all the directions investigated. To investigate the mechanical history, a round cross-section of the Ni54.2Mn29.4Ga16.4 sample was machined using a milling machine along the longitudinal axis so that both sides of the sample were symmetrical. This sample treatment changed the dilatation characteristics of the martensite and austenite. The study and analysis of the dilatation characteristics of the thermal cycle showed the relaxation of internal stresses and the reorientation of the martensitic variants.

  14. Hydrogen Migration and Vinylidene Pathway for Formation of Methane in the 193 nm Photodissociation of Propene: CH3CH=CH2 and CD3CD=CD2

    Science.gov (United States)

    Zhao, Yi-Lei; Laufer, Allan H.; Halpern, Joshua B.; Fahr, Askar

    2007-01-01

    Photodissociation channels and the final product yields from the 193 nm photolysis of propene-h6 (CH2=CHCH3) and propene-d6 (CD2=CDCD3) have been investigated, employing gas chromatography, mass spectroscopy, and flame ionization (GC/MS/FID) detection methods. The yields of methane as well as butadiene relative to ethane show considerable variations when propene-h6 or propene-d6 are photolyzed. This suggests significant variances in the relative importance of primary photolytic processes and/or secondary radical reactions, occurring subsequent to the photolysis. Theoretical calculations suggest the potential occurrence of an intramolecular dissociation through a mechanism involving vinylidene formation, accompanied by an ethylenic H-migration through the pi-orbitals. This process affects the final yields of methane-h4 versus methane-d4 with respect to other products. The product yields from previous studies of the 193 nm photolysis of methyl vinyl ketone-h6 and -d6 (CH2=CHCOCH3, CD2=CDCOCD3), alternative precursors for generating methyl and vinyl radicals, are compared with the current results for propene.

  15. Acetylene C-H bond dissociation energy using 193. 3-nm photolysis and sub-doppler resolution H-atom spectroscopy: 127 + 1. 5 kcal mol sup minus 1

    Energy Technology Data Exchange (ETDEWEB)

    Segall, J. Lavi, R.; Wen, Y.; Wittig, C. (Univ. of Southern California, Los Angeles (USA))

    1989-10-19

    H atoms are produced by 193.3-nm C{sub 2}H{sub 2} photolysis and probed spectroscopically with sub-Doppler resolution at Lyman-{alpha} by using two-photon, two-frequency ionization, for both expansion-cooled and effusive samples. The maximum Doppler shifts are in agreement with D{sub 0}(C{sub 2}H-H) = 127 {plus minus} 1.5 kcal mol{sup {minus}1}, assuming (i) that the fastest H atoms are produced concomitantly with unexcited C{sub 2}H and (ii) that vibrationally excited C{sub 2}H{sub 2} parent is not the source of these fast H atoms. In the sense that higher detection sensitivity might allow observation of faster H atoms, 127 {plus minus} 1.5 kcal mol{sup {minus}1} is an upper limit.

  16. A damage assessment model of oil spill accident combining historical data and satellite remote sensing information: a case study in Penglai 19-3 oil spill accident of China.

    Science.gov (United States)

    Wei, Lai; Hu, Zhuowei; Dong, Lin; Zhao, Wenji

    2015-02-15

    Oil spills are one of the major sources of marine pollution; it is important to conduct comprehensive assessment of losses that occur as a result of these events. Traditional methods are required to assess the three parts of losses including cleanup, socioeconomic losses, and environmental costs. It is relatively slow because assessment is complex and time consuming. A relatively quick method was developed to improve the efficiency of assessment, and then applied to the Penglai 19-3 accident. This paper uses an SAR image to calculate the oil spill area through Neural Network Classification, and uses historical oil-spill data to build the relationship between loss and other factors including sea-surface wind speed, and distance to the coast. A multiple regression equation was used to assess oil spill damage as a function of the independent variables. Results of this study can be used for regulating and quickly dealing with oil spill assessment.

  17. 18 June 2012 - DST Global Founder Y. Milner signing the guest book with Head of International Relations F. Pauss; visiting the AD facility in building 193 with AEGIS Collaboration Spokesperson M. Doser and Adviser for the Russian Federation T. Kurtyka. Managing Director I. Osborne also present with Mrs J. Milner and DST Global A. Lebedkina.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    18 June 2012 - DST Global Founder Y. Milner signing the guest book with Head of International Relations F. Pauss; visiting the AD facility in building 193 with AEGIS Collaboration Spokesperson M. Doser and Adviser for the Russian Federation T. Kurtyka. Managing Director I. Osborne also present with Mrs J. Milner and DST Global A. Lebedkina.

  18. Proton-proton correlations in central collisions of Ni-Ni at 1.93 A.GeV and the space-time extent of the emission source

    Energy Technology Data Exchange (ETDEWEB)

    Kotte, R. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Biegansky, J. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Moesner, J. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Neubert, W. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Plettner, C. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Wohlfarth, D. [Forschungszentrum Rossendorf e.V. (FZR), Dresden (Germany); Alard, J.P.; Amouroux, V.; Basrak, Z.; Bastid, N.; Belyaev, I.; Best, D.; Buta, A.; Caplar, R.; Cindro, N.; Coffin, J.P.; Crochet, P.; Dona, R.; Dupieux, P.; Dzelalija, M.; Eskef, M.; Fintz, P.; Fodor, Z.; Fraysse, L.; Genoux-Lubain, A.; Goebels, G.; Gobbi, A.; Guillaume, G.; Haefele, E.; Herrmann, N.; Hildenbrand, K.D.; Hoelbling, S.; Hong, B.; Jundt, F.; Kecskemeti, J.; Kirejczyk, M.; Korolija, M.; Kuhn, C.; Lebedev, A.; Legrand, I.; Leifels, Y.; Maazouzi, C.; Manko, V.; Merlitz, H.; Mohren, S.; Pelte, D.; Petrovici, M.; Pinkenburg, C.; Pras, P.; Rami, F.; Reisdorf, W.; Ritman, J.L.; Roy, C.; Schuell, D.; Seres, Z.; Sikora, B.; Simion, V.; Siwek-Wilczynska, K.; Sodan, U.; Somov, A.; Tizniti, L.; Trzaska, M.; Vasiliev, M.A.; Wagner, P.; Wang, G.S.; Wienold, T.; Yatsunenko, Y.; Zhilin, A.; FOPI Collaboration

    1997-02-01

    Small-angle correlations of proton pairs produced in central Ni+Ni collisions at a beam energy of 1.93 A.GeV are investigated with the FOPI detector system at GSI Darmstadt. A well-defined emission source is selected by triggering on central events which comprise about 8% of the total cross section. Simultaneous comparison of longitudinal and transverse correlation functions with the predictions of the Koonin model allows to unravel the space-time ambiguity of the emission process. Taking into account the strong collective expansion of the participant zone, which introduces a reduction of the extracted source radius of more than 30%, r.m.s. radius and emission time parameters of R{sub rms} = (4.2{+-}1.2) fm and t{sub rms} = (11{sup +7}{sub -5}) fm/c are extracted, respectively. In contrast, the analysis of the angle-integrated correlation function gives an upper limit R{sub rms} = (7.0 {+-} 1.4) fm of the source radius. (orig.)

  19. {sup 18}F-FDG PET and conventional imaging for assessment of Hodgkin's disease and non Hodgkin's lymphoma. An analysis of 193 patient studies

    Energy Technology Data Exchange (ETDEWEB)

    Bucerius, J. [Dept. of Nuclear Medicine, Univ. Hospital of Bonn (Germany); Herkel, C.; Moser, E. [Dept. of Nuclear Medicine, Univ. Hospital of Freiburg (Germany); Joe, A.Y.; Reinhardt, M.J. [Dept. of Nuclear Medicine, Univ. Hospital of Bonn (Germany); Dept. of Nuclear Medicine, Univ. Hospital of Freiburg (Germany); Altehoefer, C. [Dept. of Radiology, Univ. Hospital of Freiburg (Germany); Finke, J. [Dept. of Hematology and Oncology, Univ. Hospital of Freiburg (Germany)

    2006-07-01

    The aim of this study was to assess the diagnostic value of FDG-PET and conventional imaging (CI) in a large series of patient with Hodgkin's disease (HD) or non-Hodgkin's lymphoma (NHL) at three time points during their course of disease. Patients, methods: 169 consecutive lymphoma patients (69 HD; 100 NHL) were included. 193 FDG-PET studies were performed for staging at baseline in 42 cases, for post-therapeutic monitoring in 103, and for diagnosis of recurrence in 48 cases. Performance indices of sensitivity, specificity, positive (PPV) and negative predictive value (NPV), and accuracy of metabolic FDG-PET and morphological CI were calculated. Differences in staging and diagnosis of residual or recurrent lymphoma were compared. Results: FDG-PET changed staging in 36% of cases for staging at baseline, in 52% of cases for monitoring response to treatment, and in 29% for diagnosis of recurrence. FDG-PET staging results were confirmed in 80% for staging at baseline, in 74% for monitoring response to treatment, and in 50% for diagnosis of recurrence. FDG-PET and CI differed significantly at monitoring response to treatment for sensitivity (0.91 versus 0.69; p < 0.02), specificity (0.90 versus 0.38; p < 0.00001), PPV (0.77 versus 0.42; p < 0.001), and accuracy (0.83 versus 0.55; p < 0.02). Conclusion: FDG-PET should be considered as the diagnostic modality of choice for post-therapeutic assessment of lymphoma patients and may be a reliable alternative to CI for staging at baseline and diagnosis of recurrence. (orig.)

  20. 12 CFR 19.3 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... administrative law judge's staff who has not engaged in an investigative or prosecutorial role in a proceeding... Federal Deposit Insurance Corporation (“FDIC”), the Office of Thrift Supervision (“OTS”), and the...

  1. Das deutsche Kriegsgefangenenwesen 1939 - 1945

    OpenAIRE

    Geck, Stefan

    1998-01-01

    Zusammenfassung: Die vorliegende Untersuchung zum deutschen Kriegsgefangenenwesen (KGW) im Zweiten Weltkrieg schließt eine wichtige Lücke innerhalb der geschichtswissenschaftlichen Forschungen zum Themenkreis der Kriegsgefangenschaft in deutschem Gewahrsam. Bisherige Studien (bis einschließlich 1997) behandeln vor allem sozial- und kulturgeschichtliche Aspekte der Kriegsgefangenen (Kgf.), der Lagergesellschaft und dem Alltag von Soldaten in Kriegsgefangenschaft. Der Verfasser indes legt mit s...

  2. Reference: 193 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ous electrophysiological studies as the slow vacuolar channel. Slow vacuolar chan...scisic acid-induced repression of germination and in the response of stomata to extracellular calcium. These studies

  3. 49 CFR 193.2007 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES... impounding space. Liquefied natural gas or LNG means natural gas or synthetic gas having methane (CH4) as its... used for liquefying natural gas or synthetic gas or transferring, storing, or......

  4. Structural magnetic and magnetostrictive properties of Tb{sub 0.3}Dy{sub 0.7−x}Nd{sub x}Fe{sub 1.93} [x = 0, 0.05, 0.1, 0.15 and 0.2] compounds

    Energy Technology Data Exchange (ETDEWEB)

    Narayana Jammalamadaka, S., E-mail: surya@iith.ac.in [Advanced Magnetic Materials Laboratory, Department of Physics, Indian Institute of Technology Madras, Chennai 600036 (India); Magnetic Materials and Device Physics Laboratory, Department of Physics, Indian Institute of Technology Hyderabad, Hyderabad 502205 (India); Markandeyulu, G. [Advanced Magnetic Materials Laboratory, Department of Physics, Indian Institute of Technology Madras, Chennai 600036 (India); Balasubramaniam, Krishnan [Centre for Non Destructive Evaluation, Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai 600036 (India); Arout Chelvane, J. [Defence Metallurgical Research Laboratory, Hyderabad 500058 (India)

    2015-03-05

    Highlights: • Easy magnetization direction (EMD) for x = 0.2 compound it is towards 〈1 1 0〉. • Structural distortion from rhombohedral to orthorhombic from x = 0 to x = 0.2. • Tb{sub 0.3}Dy{sub 0.6}Nd{sub 0.1}Fe{sub 1.93} has a large magnetostriction and a low anisotropy. - Abstract: We report on the results pertinent to structural, magnetic, magnetostrictive studies of the Tb{sub 0.3}Dy{sub 0.7−x}Nd{sub x}Fe{sub 1.93} [x = 0, 0.05, 0.1, 0.15 and 0.2] compounds. From the evidenced magnetization and magnetostriction results, the crucial finding that we emphasize is that the realization of minimum anisotropy for the compound with the composition x = 0.1. From the X-ray diffraction on magnetically aligned samples, (4 4 0) peak splitting analysis and Mössbauer studies, we ascertain that the easy magnetization direction (EMD) for x = 0.2 compound it is towards 〈1 1 0〉. Above results also affirmed that indeed there exists transformation of the structural distortion from rhombohedral to orthorhombic from x = 0 to x = 0.2. The Laves phase compound Tb{sub 0.3}Dy{sub 0.6}Nd{sub 0.1}Fe{sub 1.93} with a large magnetostriction (λ{sub 111} ≈ 1270 × 10{sup −6}) and a low anisotropy may be a potential candidate for magnetostriction applications.

  5. Structural, magnetic and magnetostrictive properties of Laves-phase compounds Tb{sub x}Ho{sub 0.9−x}Nd{sub 0.1}Fe{sub 1.93} (0 ≤ x ≤ 0.40)

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Z.B. [Faculty of Materials Science and Chemical Engineering, and Department of Physics, Ningbo University, Ningbo 315211 (China); Liu, J.J., E-mail: liujinjun1@nbu.edu.cn [Faculty of Materials Science and Chemical Engineering, and Department of Physics, Ningbo University, Ningbo 315211 (China); Liu, X.Y.; Wang, J. [Faculty of Materials Science and Chemical Engineering, and Department of Physics, Ningbo University, Ningbo 315211 (China); Du, J. [Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Si, P.Z. [Zhejiang Key Lab on Magnetic Materials, China Jiliang University, Hangzhou 310018 (China)

    2014-11-14

    The structural, magnetic and magnetostrictive properties of Tb{sub x}Ho{sub 0.9−x}Nd{sub 0.1}Fe{sub 1.93} (0 ≤ x ≤ 0.40) alloys have been investigated by means of X-ray diffraction (XRD), a vibrating sample magnetometer and a standard strain technique. Single Laves phase (Tb,Ho,Nd)Fe{sub 2} compounds with a cubic MgCu{sub 2}-type structure have been synthesized at equilibrium conditions with ambient pressure. The lattice parameter of the Laves phase increases linearly with increasing Tb content and obeys the linear Vegard's law. The easy magnetization direction (EMD) at room temperature rotates continuously from <100> for x = 0.10 to <111> for x = 0.25 through an intermediate direction <110> around x = 0.15, subjected to the anisotropy compensation between Tb{sup 3+} and Ho{sup 3+} ions. The splitting of (440) XRD peak accompanied by the spontaneous magnetostriction-induced rhombohedral distortion is observed for the compounds of x ≥ 0.2, and the spontaneous magnetostriction coefficient λ{sub 111} is found to increase with increasing Tb content. The analysis of XRD, EMD, magnetization and magnetostriction shows that the pseudobinary system Tb{sub x}Ho{sub 0.9−x}Nd{sub 0.1}Fe{sub 1.93} is an anisotropy compensation system and the compensation point is realized around x = 0.25. The Nd-containing Tb{sub 0.25}Ho{sub 0.65}Nd{sub 0.1}Fe{sub 1.93} Laves-phase compound has good magnetostrictive properties, that is, a large saturation magnetostriction (λ{sub S}∼585 ppm) and a low magnetocrystalline anisotropy at room temperature, which may make it technological interest for magnetostriction applications. - Highlights: • A single (Tb,Ho,Nd)Fe{sub 2} Laves phase with a cubic MgCu{sub 2}-type structure is formed. • Anisotropy compensation has been realized for the Tb{sub x}Ho{sub 0.9−x}Nd{sub 0.1}Fe{sub 1.93} alloys. • A large saturation magnetostriction (λ{sub S} ∼ 585 ppm) is obtained for x = 0.25.

  6. Optimization on magnetic anisotropy and magnetostriction in Tb{sub x}Ho{sub 0.8−x}Pr{sub 0.2}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} compounds

    Energy Technology Data Exchange (ETDEWEB)

    Liu, X.Y. [Faculty of Materials Science & Chemical Engineering, Ningbo University, Ningbo 315211 (China); Liu, J.J., E-mail: liujinjun1@nbu.edu.cn [Faculty of Materials Science & Chemical Engineering, Ningbo University, Ningbo 315211 (China); Pan, Z.B.; Song, X.H.; Zhang, Z.R. [Faculty of Materials Science & Chemical Engineering, Ningbo University, Ningbo 315211 (China); Du, J. [Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201 (China); Ren, W.J. [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China)

    2015-10-01

    The structure, magnetocrystalline anisotropy compensation, magnetic properties, and magnetostriction of Tb{sub x}Ho{sub 0.8–x}Pr{sub 0.2}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} (0≤x≤0.30) polycrystalline alloys have been investigated. X-ray diffraction (XRD) analysis shows that all the alloys stabilize in the single Laves phase with a MgCu{sub 2}-type cubic structure. The lattice parameter, Curie temperature and saturation magnetization monotonically increase with increasing Tb content. The easy magnetization direction (EMD) at room temperature is detected rotating from the <100> axis (x≤0.10) to the <111> axis (x≥0.15), accompanied by a rhombohedral distortion with large spontaneous magnetostriction coefficients λ{sub 111}. The analysis of XRD, EMD and magnetostriction shows that Tb{sub x}Ho{sub 0.8–x}Pr{sub 0.2}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} is an anisotropy compensation system, and the critical compensation point is realized around x=0.15, which shifts to the Tb-poor side compared with the Pr-free counterpart. An optimized effect on magnetostriction especially at a relatively low field (λ{sub S}~445 ppm, λ{sub a}~510 ppm/3 kOe) was obtained in Tb{sub 0.15}Ho{sub 0.65}Pr{sub 0.2}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} compound, which is much larger than that of the Pr-free counterpart Tb{sub 0.15}Ho{sub 0.85}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} (λ{sub S}~300 ppm) and the Tb{sub 0.15}Ho{sub 0.85}Fe{sub 2} (λ{sub S}~325 ppm), due to the 20 at% Pr introduction. Low content of heavy rare earth Tb, low anisotropy, high saturation magnetostriction and large low-field magnetostriction are obtained in Tb{sub 0.15}Ho{sub 0.65}Pr{sub 0.2}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} compound, which may make it a promising magnetostrictive material. - Highlights: • The minimum anisotropy is realized around x=0.15. • EMD at RT is detected rotating from <100> to <111> axis with increasing Tb content. • A large saturation magnetostriction (λ{sub S}~445 ppm) is obtained

  7. Final Report for grant entitled "Production of Astatine-211 for U.S. Investigators"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott

    2012-12-12

    Alpha-particle emitting radionuclides hold great promise in the therapy of cancer, but few alpha-emitters are available to investigators to evaluate. Of the alpha-emitters that have properties amenable for use in humans, 211At is of particular interest as it does not have alpha-emitting daughter radionuclides. Thus, there is a high interest in having a source of 211At for sale to investigators in the US. Production of 211At is accomplished on a cyclotron using an alpha-particle beam irradiation of bismuth metal. Unfortunately, there are few cyclotrons available that can produce an alpha particle beam for that production. The University of Washington has a cyclotron, one of three in the U.S., that is currently producing 211At. In the proposed studies, the things necessary for production and shipment of 211At to other investigators will be put into place at UW. Of major importance is the efficient production and isolation of 211At in a form that can be readily used by other investigators. In the studies, production of 211At on the UW cyclotron will be optimized by determining the best beam energy and the highest beam current to maximize 211At production. As it would be very difficult for most investigators to isolate the 211At from the irradiated target, the 211At-isolation process will be optimized and automated to more safely and efficiently obtain the 211At for shipment. Additional tasks to make the 211At available for distribution include obtaining appropriate shipping vials and containers, putting into place the requisite standard operating procedures for Radiation Safety compliance at the levels of 211At activity to be produced / shipped, and working with the Department of Energy, Isotope Development and Production for Research and Applications Program, to take orders, make shipments and be reimbursed for costs of production and shipment.

  8. Production of Astatine-211 at the Duke University Medical Center for its regional distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, Michael [Duke University Medical Center, Durham, NC (United States)

    2016-01-01

    Systemic targeted radiation therapy and radioimmunotherapy continue to be important tools in the treatment of certain cancers. Because of their high energy and short path length, alpha particle emitters such as 211At are more effective than either external beam x- ray or in vivo beta radiation in delivering potentially curative doses of radiation. The limited clinical trials that have been conducted to date have yielded encouraging responses in some patients, e.g., malignant brain tumors. In order to escalate the additional necessary research and development in radiochemistry, radiobiology and efficacy evaluation of alpha particle radiotherapeutics, it is universally agreed that access to an affordable, reliable supply of 211At is warranted. In conjunction with the Department of Energy's intent to enhance stable and radioactive isotope availability for research applications, it is the primary objective of this project to improve 211At production and purification capabilities at Duke so that this radionuclide can be supplied to researchers at other institutions throughout the US.The most widely used 211At production method involves the α,2n reaction on Bismuth using a cyclotron with beams ≤ 28 MeV. Yields can be enhanced with use of an internal target that allows for a higher alpha fluence plus efficient heat dissipation in the target. Both of these items are in place at Duke; however, in order to support production for multi-institutional use, irradiation campaigns in excess of 50 µAp and four hours duration will be needed. Further, post-irradiation processing equipment is lacking that will enable the distribution process. Financial support is sought for i) a shielded, ventilated processing/containment hood; ii) development of a post-irradiation target retrieval system; iii) fabrication of a 211At distillation and recovery module and iv) a performance review and, where needed, an enhancement of seven major subsystems that comprise the CS-30 Cyclotron. With these modifications in place, routine production of ≥200 mCi of At-211 should be readily achievable, given our methodological development of At-211 target preparation, internal target irradiation and dry distillation to recover the radionuclide.

  9. Genotyping of HFE c.845G>A, HFE c.187C>G and HFE c.193A>T for hemochormatosis by Real Time-Polymerase Chain Reaction  : A quality improvement study in the Region Jönköping County

    OpenAIRE

    Chamoun, Stephanie; Medina, Sarajlic

    2016-01-01

    Hereditär hemokromatos (HH) är en vanlig multigenetisk defekt som leder till ett onormalt förhöjt järnupptag i tarmen och ses framförallt hos kaukasisk befolkning. Sjukdomen har på senare år visats orsakats av mutationen c.845G>A men även mer ovanliga varianter som c.187C>G och c.193A>T, vilka alla finns belägna i genen HFE. HFE som finns lokaliserad intill Human Leukocyte Antigen (HLA)-genen på kromosom sex korta arm kodar för ett HFE-protein som har till uppgift att reglera kroppen...

  10. Enhanced magnetostrictive effect in epoxy-bonded Tb{sub x}Dy{sub 0.9−x}Nd{sub 0.1}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} pseudo 1–3 particulate composites

    Energy Technology Data Exchange (ETDEWEB)

    Liu, J. J., E-mail: liujinjun1@nbu.edu.cn, E-mail: liujjimr@gmail.com; Pan, Z. B.; Song, X. H.; Zhang, Z. R. [Faculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211 (China); Ren, W. J. [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China)

    2015-05-07

    The spin configuration and spontaneous magnetostriction λ{sub 111} of Tb{sub x}Dy{sub 0.9−x}Nd{sub 0.1}(Fe{sub 0.8}Co{sub 0.2}){sub 1.93} (0.20 ≤ x ≤ 0.60) alloys have been investigated. The easy magnetization direction (EMD) at room temperature was observed towards the 〈111〉 axis when 0.40 ≤ x ≤ 0.60, accompanied by a rhombohedral distortion with large spontaneous magnetostriction coefficients λ{sub 111}, which increases from 1640 ppm for x = 0.40 to 1900 ppm for x = 0.60. The strong 〈111〉-oriented pseudo 1–3 particulate composite was fabricated by embedding and aligning particles in a passive epoxy matrix under an applied magnetic field. An enhanced magnetostrictive effect, the large low-field magnetostriction, λ{sub a}, as high as 480 ppm at 3 kOe, was obtained for the sample of x = 0.40, in an excess of 75% of its polycrystalline alloy although it only contains 27 vol. % alloy particles. This enhanced effect can be attributed to its low magnetic anisotropy, anisotropic magnetostrictive nature (e.g., λ{sub 111} ≠ λ{sub 100,} 〈111〉EMD), chain structure, and the 〈111〉-textured orientation. In addition, we give a direct experimental support that the 〈111〉EMD of particle and the strong 〈111〉-textured orientation are the crucial factors to realize the enhanced magnetostrictive effect in 1–3 particulate composites.

  11. 40 CFR 264.193 - Containment and detection of releases.

    Science.gov (United States)

    2010-07-01

    ... wastes or accumulated liquid out of the system to the soil, ground water, or surface water at any time... tanks must include one or more of the following devices: (1) A liner (external to the tank); (2) A vault... containment systems must satisfy the following requirements: (1) External liner systems must be: (i)...

  12. 40 CFR 265.193 - Containment and detection of releases.

    Science.gov (United States)

    2010-07-01

    ... prevent any migration of wastes or accumulated liquid out of the system to the soil, ground water, or... devices: (1) A liner (external to the tank); (2) A vault; (3) A double-walled tank; or (4) An equivalent...: (1) External liner systems must be: (i) Designed or operated to contain 100 percent of the...

  13. 34 CFR 668.193 - Loan servicing appeals.

    Science.gov (United States)

    2010-07-01

    ... EDUCATION, DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Two Year Cohort Default Rates § 668... that the FFEL Program lender or the Direct Loan Servicer, as defined in 34 CFR 685.102, failed to... identifies a sample that is large enough to derive an estimate, acceptable at a 95 percent confidence...

  14. 46 CFR 193.10-5 - Fire pumps.

    Science.gov (United States)

    2010-10-01

    ... Minimum number of pumps Hose and hydrant size, inches Nozzle orifice size, inches Length of hose, feet 100... tube pressure may not be less than 35 p.s.i. (d) Fire pumps shall be fitted on the discharge side with... this amount. (e) Fire pumps shall be fitted with a pressure gage on the discharge side of the pumps....

  15. Dicty_cDB: VSA193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available us sp. cDNA clone RSPBK07 3' end, mRNA sequence. 46 2e-15 4 BQ194903 |BQ194903.1 UI-R-CN1-cmb-p-04-0-UI.s1 U...I-R-CN1 Rattus norvegicus cDNA clone UI-R-CN1-cmb-p-04-0-UI 3', mRNA sequence. 46

  16. 19 CFR 191.193 - Application procedure for compliance program.

    Science.gov (United States)

    2010-04-01

    ..., address, IRS number (with suffix), and the type of business in which engaged, as well as the name(s) of... program, including the retention period and method (for example, paper, electronic, etc.); (4) A list...

  17. 46 CFR 193.10-10 - Fire hydrants and hose.

    Science.gov (United States)

    2010-10-01

    ... shaft alleys containing no assigned space for the stowage of combustibles. Fire hydrants must be... be provided with a single length of hose with nozzle attached and a spanner. A suitable hose rack or other device shall be provided for the proper stowage of the hose. If the hose is not stowed in the...

  18. Dicty_cDB: VFL193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available e B: gllekhlkkskkinikqi*k*kcqvvemvvii*kilaiilkkllfnhqkkqlql*ynkil milkq*hhh*sqnplvavlvkinhhhhhhvvvvviklkknkn...***s*rktkirllwr**kkwiiiml*irind nnnnnk*tnkr*fkyfikw--- ---qfqs*wvlinckl*iqsmvgfhqrcnkqimilkscllvfywvplmhl*fg...MGVDKLQIINSEYGWIPPKVQQANHDIKVMSVGFLLGTPDAPVIWKGPRKTT MIRRFLKDTFWGKQDYLIIDTPPGTSDEHLSIINSLKSCNPDGAVLVTTPQDLSC...PKLMGVDKLQIINSEYGWIPPKVQQANHDIKVMSVGFLLGTPDAPVIWKGPRKTT MIRRFLKDTFWGKQDYLIIDTPPGT

  19. Inside Hall 193 for the Antiproton Accumulator (AA) ring

    CERN Multimedia

    1979-01-01

    Installation work is in full swing. A model quadrupole on the left shows where the magnet ring will be. The cables wound on drums are part of the pulse-forming network for the injection kicker. See Annual Report 1979 p. 103, Fig. 9 and photo 7911303. For photos of the AA in different phases of completion (between 1979 and 1982) see: 7911303, 7911597X, 8004261, 8004608X, 8005563X, 8005565X, 8006716X, 8006722X, 8010939X, 8010941X, 8202324, 8202658X, 8203628X .

  20. 46 CFR 193.05-10 - Fixed fire extinguishing systems.

    Science.gov (United States)

    2010-10-01

    ... of the foam system shall be as set forth in part 95 of Subchapter I (Cargo and Miscellaneous Vessels) of this chapter. (f) Where an enclosed ventilating system is installed for electric propulsion motors... VESSELS FIRE PROTECTION EQUIPMENT Fire Detecting and Extinguishing Equipment, Where Required §...

  1. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Science.gov (United States)

    2010-07-01

    ...′30″, 3,100 yards southeast of FW South Channel Light and 5,250 yards south of FW North Channel Light... northeast of the north entrance channel to Port St. Joe, Florida. (2) Explosives Anchorage Area 2....

  2. Dicty_cDB: AFN193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available skestikcc*fitikf*fscfr*ikecfs*ilct mvwslqkvnarl*npw*hlrq*krcchrqn*lrcc**qshllqiwxhwxxntq--- ---hqiliqlf*inqr...DSVVLDKSKNVLVEFYAP WCGHCKKLMPDYEILGNTYANEKDVVIAKIDCDAADNKAICXKYGVTGXPTLK--- ---ikf*fscfr*ikecfs*ilctmvwsxqkvnar

  3. 38 CFR 19.3 - Assignment of proceedings.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Assignment of proceedings... Assignment of proceedings. (a) Assignment. The Chairman may assign a proceeding instituted before the Board, including any motion, to an individual Member or to a panel of three or more Members for adjudication...

  4. Dicty_cDB: SFL193 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available skt*m*m**sw*kmlcxdsl**sl*frlwxrf*mxn*t*wfrxlcpfrktx xttt*km**xmptrp*mxsxstwkrmlrccpxttxkmlfkmsxkt*m*sqplw*rm...GVKXXP*ixvh*rxphxheckvdpngkemlrqip*ttt trslfikmpskt*m*m**sw*kmlcxdsl**sl*frlwxrf*mxn*t*wfrxlcpfrktx xttt*km*...l *ryi*ylyi*k*ll*kfiq*psc*sik*mlqs*wiy*nynsnrvflf*cqd*rmclir*i m*fpkxllfksnfllpr*inl*rfklw--- ---*rcppnhexrf...ndqxhqxwgkgspmnxcsltxxxxp*m*s*sqw*rnvasdpidhhh qkfvh*dalqnmnvnvmimvknvvxrfivmkfvi*ivvevlnv*ldmmvqxvvsvqkdxt

  5. 14 CFR 21.193 - Experimental certificates: general.

    Science.gov (United States)

    2010-01-01

    ... three-view dimensioned photographs of the aircraft. (e) In the case of a light-sport aircraft assembled... aircraft kit manufacturer and issued a special airworthiness certificate in the light-sport category. (2... manufactured outside of the United States, evidence that the aircraft kit was manufactured in a country...

  6. 37 CFR 2.193 - Trademark correspondence and signature requirements.

    Science.gov (United States)

    2010-07-01

    ... who has an actual written or verbal power of attorney or an implied power of attorney from the owner... questions the authority of a person who signs a communication that merely transmits paper documents. (f... advocating) of any document by any person, whether a practitioner or non-practitioner, constitutes...

  7. Evaluation of Novel Wet Chemistry Separation and Purification Methods to Facilitate Automation of Astatine-­211 Isolation

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott [Univ. of Washington, Seattle, WA (United States)

    2016-07-19

    This research is a collaborative effort between the research groups of the PIs, Dr. D. Scott Wilbur in the Department of Radiation Oncology at the University of Washington (UW) and Matthew O’Hara at the Pacific Northwest National Laboratory (PNNL). In this report only those studies conducted at UW and the budget information from UW will be reported. A separate progress and financial report will be provided by PNNL. This final report outlines the experiments (Tasks) conducted and results obtained at UW from July 1, 2013 thru June 30, 2016 (2-­year project with 1 year no-­cost extension). The report divides the information on the experiments and results obtained into the 5 specific objectives of the research efforts and the Tasks within those objectives. This format is used so that it is easy to see what has been accomplished in each area. A brief summary of the major findings from the studies is provided below. Summary of Major Findings from Research/Training Activities at UW: Anion and cation exchange columns did not provide adequate 211At capture and/or extraction results under conditions studied to warrant further evaluation; PEG-­Merrifield resins containing mPEG350, mPEG750, mPEG2000 and mPEG5000 were synthesized and evaluated; All of the mPEG resins with different sized mPEG moieties conjugated gave similar 211At capture (>95%) from 8M HCl solutions and release with conc. NH4OH (~50-­80%), but very low quantities were released when NaOH was used as an eluent; Capture and release of 211At when loading [211At]astatate appeared to be similar to that of [211At]astatide on PEG columns, but further studies need to be conducted to confirm that; Capture of 211At on PEG columns was lower (e.g. 80-­90%) from solutions of 8M HNO3, but higher capture rates (e.g. 99%) can be obtained when 10M HNO3 is mixed with an equal quantity of 8M HCl; Addition of reductants to the 211At solutions did not appear to change the percent capture, but may have an effect on the % extracted; There was some indication that the PEG-­Merrifield resins could be saturated (perhaps with Bi) resulting in lower capture percentages, but more studies need to be done to confirm that; A target dissolution chamber, designed and built at PNNL, works well with syringe pumps so it can be used in an automated system; Preliminary semi-­automated 211At isolation studies have been conducted with full scale target dissolution and 211At isolation using a PEG column on the Hamilton automated system gave low overall recoveries, but HNO3 was used (rather than HCl) for loading the 211At and flow rates were not optimized; Results obtained using PEG columns are high enough to warrant further development on a fully automated system; Results obtained also indicate that additional studies are warranted to evaluate other types of columns for 211At separation from bismuth, which allow use of HNO3/HCl mixtures for loading and NaOH for eluting 211At. Such a column could greatly simplify the overall isolation process and make it easier to automate.

  8. KN193L05: WHOI cruise 193 leg 05 aboard the R/V Knorr from 2008-06-06 - 2008-06-27 (NODC Accession 0081219)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  9. Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model

    Energy Technology Data Exchange (ETDEWEB)

    Green, Damian J.; Shadman, Mazyar; Jones, Jon C.; Frayo, Shani; Kenoyer, Aimee L.; Hylarides, Mark; Hamlin, Donald K.; Wilbur, D. Scott; Balkan, Ethan R.; Lin, Yukang; Miller, Brian W.; Frost, Sophia; Gopal, Ajay K.; Orozco, Johnnie J.; Gooley, Ted; Laird, Kelley L.; Till, B. G.; Back, Tom; Sandmaier, B. M.; Pagel, John M.; Press, Oliver W.

    2015-03-26

    Alpha emitting radionuclides release a large amount of energy within a few cell diameters and may be particularly effective for radioimmunotherapy targeting minimal residual disease (MRD) conditions in which micrometastatic disease satellites are broadly distributed. To evaluate this hypothesis, 211At conjugated 1F5 mAb (anti-CD20) was studied in both bulky lymphoma tumor xenograft and MRD animal models. Superior treatment responses to 211At conjugated 1F5 mAb were evident in the MRD setting. Lymphoma xenograft tumor bearing animals treated with doses of up to 48µCi of anti-CD20 211At-decaborate [211At-B10-1F5] experienced modest responses (0% cures but 2-3-fold prolongation of survival compared to negative controls). In contrast, 70% of animals in the MRD lymphoma model demonstrated complete eradication of disease when treated with 211At-B10-1F5 at a radiation dose that was less than one-third (15 µCi) of the highest dose given to xenograft animals. Tumor progression among untreated control animals in both models was uniformly lethal. After 130 days, no significant renal or hepatic toxicity is observed in the cured animals receiving 15 µCi of 211At-B10-1F5. These findings suggest that in a MRD lymphoma model, where isolated cells and tumor microclusters prevail, α-emitters may be uniquely efficacious.

  10. SU-E-T-193: FMEA Severity Scores - Do We Really Know?

    Energy Technology Data Exchange (ETDEWEB)

    Khan, A; Robertson, JD; Narra, V; Yue, N; Howell, R

    2014-06-01

    Purpose: Mycosis fungoides is a common form of cutaneous T-cell lymphoma which generally affects the skin. A typical course of treatment may include fractionated total skin electron beam therapy. Given the difficulties in uniformly irradiating some regions of the body and the need for frequent visits within the context of a fractionated protocol, this study investigated the feasibility of delivering the dose using form-fitting cloth which contained phosphorous-32 as a source for beta particle irradiation. Methods: A piece of fabric (0.97 g) consisting of a blend of spandex and flame retardant material impregnated with phosphorus-31 (2000 ppm) was bombarded with neutrons to produce phosphorus-32. The cloth was then laid flat and a stack of radiochromic film placed on top. Sheets of film and tissue equivalent plastic were layered to form a stack measuring a total of 1 cm thickness and remained sandwiched for 77.3 hr. Results: The initial activity of the activated cloth was 44 μCi of P-32. The absorbed dose was uniform within planes parallel to the cloth and exponentially dependent on depth, delivering 560cGy at 0.3mm and falling to 20cGy at 3mm. Conclusion: The total dose prescribed for a typical course of TSET for mycosis fungoides is 36Gy delivered over 9 weeks and is expected to treat to at least 5mm depth. Therefore, the P-32 impregnated cloth may not be clinically indicated to treat this disease given the unfavorable depth-dose characteristics. However, a major advantage of using form-fitting cloth is the uniformity with which the dose could be delivered over the skin in areas which are not flat. Increasing the distance between cloth and skin could improve the depth-dose characteristics.

  11. 31 CFR 103.193 - Special measures against Banco Delta Asia.

    Science.gov (United States)

    2010-07-01

    ... FINANCIAL RECORDKEEPING AND REPORTING OF CURRENCY AND FOREIGN TRANSACTIONS Anti-Money Laundering Programs...-money laundering program requirement; (viii) A broker or dealer in securities registered, or required to... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Special measures against Banco...

  12. Conformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I

    DEFF Research Database (Denmark)

    Petrlova, Jitka; Bhattacherjee, Arnab; Boomsma, Wouter Krogh;

    2014-01-01

    Several disease-linked mutations of apolipoprotein A-I, the major protein in high-density lipoprotein (HDL), are known to be amyloidogenic, and the fibrils often contain N-terminal fragments of the protein. Here, we present a combined computational and experimental study of the fibril-associated ......Several disease-linked mutations of apolipoprotein A-I, the major protein in high-density lipoprotein (HDL), are known to be amyloidogenic, and the fibrils often contain N-terminal fragments of the protein. Here, we present a combined computational and experimental study of the fibril...... that these conformational shifts match well with the effects of these mutations in thioflavin T fluorescence and transmission electron microscopy experiments. Together, our results point to molecular mechanisms that may have a key role in disease-linked aggregation of apolipoprotein A-I....

  13. Long Coherence Length 193 nm Laser for High-Resolution Nano-Fabrication

    Science.gov (United States)

    2008-06-27

    laser spectral bandwidth to coherence length and the measurement method used. A Michelson interferometer was used to directly measure the coherence...Using the SNLO non-linear optics modeling program and new fiber laser models both developed at Sandia National Labs, we were able to analyze pulsed and...scattering preclude pulsed fiber laser amplifiers from meeting our required power and coherence specifications. While CW fiber laser amplifiers are

  14. 47 CFR 95.193 - (FRS Rule 3) Types of communications.

    Science.gov (United States)

    2010-10-01

    ... information, transmit a brief text message, make a voice page, or to conduct a brief test. (b) Non-voice... of communications. (a) You may use an FRS unit to conduct two-way voice communications with another person. You may use an FRS unit to transmit one-way voice or non-voice communications only to...

  15. 19 CFR 19.3 - Bonded warehouses; alterations; relocation; suspensions; discontinuance.

    Science.gov (United States)

    2010-04-01

    ... through fraud or the misstatement of a material fact; (2) The warehouse proprietor refuses or neglects to... crime. Any change in the employment status of the corporate officer, (e.g., discharge, resignation... theft, smuggling, or a theft-connected crime, resulting from acts committed while a corporate...

  16. Children poisoning by carbamate: a descriptive study - doi:10.5020/18061230.2004.p193

    Directory of Open Access Journals (Sweden)

    Luiza Jane Eyre de Souza Vieira

    2012-01-01

    Full Text Available The study had as its aim to characterize the children under 5 years old, attended with exogenous poisoning by carbamate (popularly called “chumbinho” – “small shot” at an emergency hospital in Fortaleza and to relate the signs and symptoms detected in this type of poisoning. It concerned a descriptive study, with a sample of 65 children attended during the period of 1998 to 2000, in Fortaleza, Ceará. It was noticed that the most affected age group was of those with 1 to 3 years old, not being verified any significant difference between sexes. The most evident signs and symptoms were myosis, vomits, profuse perspiration and sialorrhea and the predominant treatment was the use of active coal. It is concluded, therefore, that there is a need of putting into effect the health education, calling the society’s attention to the risks of the inadequate “chumbinho” use in the domiciliar environment.

  17. Yeast Interacting Proteins Database: YER022W, YBR193C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available n prey (YPD) 15 Literature shared by bait and prey 10 Literature sharing score 50... CuraGen (0 or 1) 0 S. Fields (0 or 1) 0 Association (0 or 1,YPD) 1 Complex (0 or 1,YPD) 1 Synthetic lethali

  18. 9 CFR 381.193 - Poultry carcasses, etc., not intended for human food.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Poultry carcasses, etc., not intended..., DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS...

  19. Women, Wit, and Witchcraft: The Burden of Stereotypes. Working Paper No. 193.

    Science.gov (United States)

    Levy, Barbara

    This paper examines the negative stereotypes so long foisted on witty women and the move of contemporary witty women writers into a comic vision beyond the imposed connection of female wit to sly cleverness and witchcraft. To illustrate how the woman writer had to cope with a prejudice against and a fear of her wit, the paper considers three…

  20. Yeast Interacting Proteins Database: YPL070W, YPR193C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available utational analysis of large-scale protein-protein interaction data suggests a possible role in transcription...in; computational analysis of large-scale protein-protein interaction data suggests a possible role in trans

  1. Health-hazard evaluation report MHETA 87-193-1865, Clarksburg Publishing Company, Clarksburg, West Virginia

    Energy Technology Data Exchange (ETDEWEB)

    Kullman, G.J.

    1987-12-01

    In response to a request from employees at the Clarksburg Publishing Company, Clarksburg, West Virginia, a study was made of work related health complaints at their Exponet Telegram Building (ETB). Particular attention was given to employees reporting symptoms of headache, sinus trouble, nasal irritation, blurred vision, dizziness, diarrhea, memory loss, muscle weakness/cramping, nausea, confusion, and chills. Of the 124 workers in the ETB, 46% completed an indoor air quality survey. Discomfort related to work was reported by about 16%, and about 5% reported work related illness. The most-prevalent medical symptom was discomfort/irritation related to cigarette smoke. Air samples indicated no contaminants present at levels above those recommended for working environments. The ventilation system for the facility was suboptimal and recommendations were offered for its improvement and routine maintenance, along with a recommendation for a restriction or ban on smoking. The author concludes that symptoms in ETB workers are consistent with tight building syndrome.

  2. 10 CFR Appendix C to Part 20 - Quantities 1 of Licensed Material Requiring Labeling

    Science.gov (United States)

    2010-01-01

    ... Polonium-205 1,000 Polonium-207 1,000 Polonium-210 0.1 Astatine-207 100 Astatine-211 10 Radon-220 1 Radon-222 1 Francium-222 100 Francium-223 100 Radium-223 0.1 Radium-224 0.1 Radium-225 0.1 Radium-226...

  3. Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia

    Science.gov (United States)

    Here we report two genomes, one complete and one draft, from virulent bovine strains of Mannheimia haemolytica(strains D171 and D35)serotype A2 recovered prior to the field usage of modern antimicrobial drugs....

  4. 41 CFR 102-193.15 - What are the records management responsibilities of the Administrator of General Services (the...

    Science.gov (United States)

    2010-07-01

    .... Records management policies and guidance established by the Archivist are contained in 36 CFR chapter XII... ensure economical and effective records management. Records management policies and guidance established... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are the...

  5. MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells

    NARCIS (Netherlands)

    J. Nyhan (Michelle); R. O'Donovan (Tracey); W.M.A. Boersma (Antonius); E.A.C. Wiemer (Erik); S.L. McKenna (Sharon)

    2016-01-01

    markdownabstract__Background:__ Successful treatment of oesophageal cancer is hampered by recurrent drug resistant disease. We have previously demonstrated the importance of apoptosis and autophagy for the recovery of oesophageal cancer cells following drug treatment. When apoptosis (with autophagy)

  6. 15 CFR Appendix B to Subpart R of... - Minor Projects for Purposes of § 922.193(a)(2)(iii)

    Science.gov (United States)

    2010-01-01

    ... structures in the vicinity and on the watercourse involved; and (ii) provide for the free littoral flow of... structure fulfills an identifiable need for erosion protection, bank stabilization, protection of uplands... pollutants, waste metal products, debris, or organic materials; (iii) the structure is not more than 300...

  7. SU-E-J-193: Application of Surface Mapping in Detecting Swallowing for Head-&-Neck Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Cao, D; Xie, X; Mehta, V; Shepard, D [Swedish Cancer Institute, Seattle, WA (United States)

    2015-06-15

    Purpose: Recent evidence is emerging that long term swallowing function may be improved after radiotherapy for head-&-neck cancer if doses are limited to certain swallowing structures. Immobilization of patients with head-&-neck cancer is typically done with a mask. This mask, however, doesn’t limit patient swallowing. Patient voluntary or involuntary swallowing may introduce significant tumor motion, which can lead to suboptimal delivery. In this study, we have examined the feasibility of using surface mapping technology to detect patient swallowing during treatment and evaluated its magnitude. Methods: The C-RAD Catalyst system was used to detect the patient surface map. A volunteer lying on the couch was used to simulate the patient under treatment. A virtual marker was placed near the throat and was used to monitor the swallowing action. The target motion calculated by the Catalyst system through deformable registration was also collected. Two treatment isocenters, one placed close to the throat and the other placed posterior to the base-of-tongue, were used to check the sensitivity of surface mapping technique. Results: When the patient’s throat is not in the shadow of the patient’s chest, the Catalyst system can clearly identify the swallowing motion. In our tests, the vertical motion of the skin can reach to about 5mm. The calculated target motion can reach up to 1 cm. The magnitude of this calculated target motion is more dramatic when the plan isocenter is closer to the skin surface, which suggests that the Catalyst motion tracking technique is more sensitive to the swallowing motion with a shallower isocenter. Conclusion: Surface mapping can clearly identify patient swallowing during radiation treatment. This information can be used to evaluate the dosimetric impact of the involuntary swallowing. It may also be used to potentially gate head-&-neck radiation treatments. A prospective IRB approved study is currently enrolling patients in our institution. Research was funded through an Elekta grant.

  8. 76 FR 53481 - Outer Continental Shelf, Alaska OCS Region, Chukchi Sea Planning Area, Oil and Gas Lease Sale 193

    Science.gov (United States)

    2011-08-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management, Regulation and Enforcement Outer Continental Shelf, Alaska OCS Region...) announces the availability of a Final Supplemental Environmental Impact Statement (SEIS) for...

  9. The CARMA Paired Antenna Calibration System: Atmospheric Phase Correction for Millimeter Wave Interferometry and its Application to Mapping the Ultraluminous Galaxy Arp 193

    CERN Document Server

    Zauderer, B Ashley; Vogel, Stuart N; Carpenter, John M; Peréz, Laura M; Lamb, James W; Woody, David P; Bock, Douglas C -J; Carlstrom, John E; Culverhouse, Thomas L; Curley, Roger; Leitch, Erik M; Plambeck, Richard L; Pound, Marc W; Marrone, Daniel P; Muchovej, Stephen J; Mundy, Lee G; Teng, Stacy H; Teuben, Peter J; Volgenau, Nikolaus H; Wright, Melvyn C H; Wu, Dalton

    2014-01-01

    Phase fluctuations introduced by the atmosphere are the main limiting factor in attaining diffraction limited performance in extended interferometric arrays at millimeter and submillimeter wavelengths. We report the results of C-PACS, the Combined Array for Research in Millimeter-Wave Astronomy Paired Antenna Calibration System. We present a systematic study of several hundred test observations taken during the 2009-2010 winter observing season where we utilize CARMA's eight 3.5-m antennas to monitor an atmospheric calibrator while simultaneously acquiring science observations with 6.1-m and 10.4-m antennas on baselines ranging from a few hundred meters to ~2 km. We find that C-PACS is systematically successful at improving coherence on long baselines under a variety of atmospheric conditions. We find that the angular separation between the atmospheric calibrator and target source is the most important consideration, with consistently successful phase correction at CARMA requiring a suitable calibrator locate...

  10. 49 CFR 40.193 - What happens when an employee does not provide a sufficient amount of urine for a drug test?

    Science.gov (United States)

    2010-10-01

    ... MRO, who has expertise in the medical issues raised by the employee's failure to provide a sufficient specimen. (The MRO may perform this evaluation if the MRO has appropriate expertise.) (1) As the MRO, if...-existing psychological disorder, but does not include unsupported assertions of “situational anxiety”...

  11. Molecular characterization of Salmonella enterica serovar 4,[5],12:i:- DT193 ASSuT strains from two outbreaks in Italy

    DEFF Research Database (Denmark)

    Barco, Lisa; Ramon, Elena; Cortini, Enzo

    2014-01-01

    profiles of resistance within this clone. Recently, strains presenting such features were isolated from two unrelated outbreaks in Italy. Strains were characterized by pulsed-field gel electrophoresis (PFGE), performed with XbaI, BlnI, and SpeI, and multiple-locus variable-number tandem repeat analysis...

  12. Detailed gravimetric geoid confirmation of short wavelength features of sea surface topography detected by the Skylab S-193 altimeter in the Atlantic Ocean

    Science.gov (United States)

    Marsh, J. G.; Vincent, S.; Mcclinton, A. T.; Chang, E. S.

    1975-01-01

    A detailed gravimetric geoid was computed for the Northwest Atlantic Ocean and Caribbean Sea area in support of the calibration and evaluation of the GEOS-C altimeter. This geoid, computed on a 15 ft. x 15 ft. grid was based upon a combination of surface gravity data with the GSFC GEM-6 satellite derived gravity data. A comparison of this gravimetric geoid with 10 passes of SKYLAB altimeter data is presented. The agreement of the two data types is quite good with the differences generally less than 2 meters. Sea surface manifestations of numerous short wavelength (approximately 100 km) oceanographic features are now indicated in the gravimetric geoid and are also confirmed by the altimetry data.

  13. Erratum: "The Eighth Data Release of the Sloan Digital Sky Survey: First Data from SDSS-III" (2011, ApJS, 193, 29)

    OpenAIRE

    Aihara, Hiroaki; Prieto, Carlos Allende; An, Deokkeun; Anderson, Scott F.; Aubourg, Éric; Balbinot, Eduardo; Beers, Timothy C.; Berlind, Andreas A.; Bickerton, Steven J.; Bizyaev, Dmitry; Blanton, Michael R.; Bochanski, John J.; Bolton, Adam S; Bovy, Jo; Brandt, W.N.

    2011-01-01

    Section 3.5 of Aihara et al. (2011) described various sources of systematic error in the astrometry of the imaging data of the Sloan Digital Sky Survey (SDSS). In addition to these sources of error, there is an additional and more serious error, which introduces a large systematic shift in the astrometry over a large area around the north celestial pole. The region has irregular boundaries but in places extends as far south as declination δ ≈ 41◦. The sense of the shift is that the positions ...

  14. Dicty_cDB: Contig-U14401-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available uery: 134 aaggtttatcngtttttangggtgatttaaagatcaaatatgaagantttcanccatatt 193 |||||||||||||||||||||||||||||||||...||||||||||||||||||||||||||| Sbjct: 134 aaggtttatcngtttttangggtgatttaaagatcaaatatgaagantttcan... 333 Query: 134 aaggtttatcngtttttangggtgatttaaagatcaaatatgaagantttcanccatatt 193 ...|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 332 aaggtttatcngtttttangggtgatttaaagatcaaatatgaagantttcan

  15. Shelf-life of ɛ-lysyl-3-(trimethylstannyl)benzamide immunoconjugates, precursors for 211At labeling of antibodies

    DEFF Research Database (Denmark)

    Aneheim, Emma; Halleröd, Jenny; Albertsson, Per;

    2015-01-01

    Astatine-211 is possibly the most promising radionuclide for targeted α-particle therapy when it comes to the treatment of occult disseminated cancer. Preclinical research has proven effective, and patient studies have been initiated based on these results. However, a lack of production capacity...

  16. Successful radioimmunotherapy of established syngeneic rat colon carcinoma with 211At-mAb

    DEFF Research Database (Denmark)

    Eriksson, Sophie E; Bäck, Tom; Elgström, Erika

    2013-01-01

    Most carcinomas are prone to metastasize despite successful treatment of the primary tumor. One way to address this clinical challenge may be targeted therapy with α-emitting radionuclides such as astatine-211 (211At). Radioimmunotherapy utilizing α-particle emitting radionuclides is considered...... colon carcinoma with tumor diameters of approximately 10 mm....

  17. Dicty_cDB: Contig-U10543-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ery: 193 aataatggggccnataataataattcanccagtggaatcattggtggttcaacaatttct 252 ||||||||||||||||||||||||||||||||||...|||||||||||||||||||||||||| Sbjct: 193 aataatggggccnataataataattcanccagtggaatcattg...gtggttcaacaatttct 252 Query: 253 ggtgaaaaggttaaaccaggggnatttgaaaaatatgtaaaagaaaagggnaatattcan 312 ||||||||||...|||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 253 ggtgaaaaggttaaaccaggggnatttgaaaaatatgtaaaagaaaagggnaatattcan...||||||| ||||||||| Sbjct: 414 atttttcaaa-acaatataaaatgtggttctctggtttaaatatgtttagtttagaaatg 472 Query: 193 aataatggggccnataataataattcan

  18. Widerstand als Farce? V-Männer in der illegalen KPD in Breslau 1935–1939 / Resistance as farce? Gestapo Informants (Vertrauensmänner) in the illegal German Communist Party in Breslau 1935–39

    OpenAIRE

    Grashoff, U. R.

    2016-01-01

    So far, little is known about the communist resistance movement during the Third Reich in Breslau. After the party was proscribed, it was possible to install new local leaders quickly, despite repeated arrests. But to what extent can the communist underground in Breslau be regarded to be genuine resistance? There is reason to believe that the party’s Silesian district leadership was controlled by the Gestapo – at least in part and to an increasing extent. This article discusses the role of th...

  19. 75 FR 28483 - Airworthiness Directives; Dowty Propellers R175/4-30-4/13; R175/4-30-4/13e; R184/4-30-4/50; R193...

    Science.gov (United States)

    2010-05-21

    ... Engineer, Boston Aircraft Certification Office, FAA, Engine and Propeller Directorate, 12 New England..., Engine and Propeller Directorate, Aircraft Certification Service. BILLING CODE 4910-13-P ...-21-AD; Amendment 39-16302; AD 2010-10-23] RIN 2120-AA64 Airworthiness Directives; Dowty...

  20. Test accuracy at different cut-offs when plasma concentrations of metabolic indicators are used to detect decreased fertility in dairy cows (Poster topic 01, Poster 27, p. 193)

    DEFF Research Database (Denmark)

    Lomander, H; Gustafsson, H; Svensson, C

    Negative energy balance is a known risk factor for decreased fertility in dairy cows. This study evaluates the accuracy of measuring plasma concentrations of two indicators of negative energy balance, non esterified fatty acids (NEFA) and β-hyrdroxy buturate (BHBA), when they are used to predict ...

  1. 跨国公司造成东道国环境损害的环境侵权法律责任--从渤海湾蓬莱19-3油田溢油事故谈起%On Environmental Tort Liability of the Host Country’ s Environmental Damage Caused by the Multinationals:Starting from the Oil Spill of Penglai 19-3 Oil Field in Bohai Bay

    Institute of Scientific and Technical Information of China (English)

    邬勇

    2014-01-01

    Currently ,the multinational companies are involved in international development and utilization of re -sources more frequently , and cases of causing damage to the environment of the host country is also increasing , such as the Bohai Bay oil spill , so that the topic as to how to determine the responsibility when a multinational causes environmental damage to the host country becomes a hot issue .Considering the social responsibility and environmental responsibility of multinational corporate , taking into account the special organizational structure of multinationals , with a view to protect the economic interests of multinationals so as to promote cross-border in-vestment as well as the environmental interests of the host country , the parent company of the multinational should bear against the supplemental liability for casuing damage to the environmental interests of the host coun -try.%当前,跨国公司参与国际资源开发利用活动越来越频繁,造成东道国环境损害的几率也越来越高,如渤海湾溢油事故。如何确定跨国公司对东道国造成环境损害的责任承担机制成为一个热门话题。从跨国公司企业的社会责任和环境公平责任出发,考虑到跨国公司特殊的组织结构形式,同时为了达到兼顾保护跨国投资者的经济利益和东道国的环境利益的目的,跨国公司母公司应承担侵害东道国环境利益的补充责任。

  2. Composição específica e abundância da ictiofauna do rio dos Padres, bacia do rio Iguaçu, Brasil - DOI: 10.4025/actascibiolsci.v28i3.193 Specific composition and abundance of the ichthyofauna from Padres’ river, Iguaçu river basin, Brazil - DOI: 10.4025/actascibiolsci.v28i3.193

    Directory of Open Access Journals (Sweden)

    Vitor André Frana

    2007-11-01

    Full Text Available A composição e estrutura das comunidades de peixes podem ser consideradas como indicadores ecológicos e ambientais, constituindo-se desta forma como ferramenta para o manejo de bacias hidrográficas. O presente estudo objetivou levantar informações sobre a composição específica e abundância da ictiofauna do rio dos Padres. Foram realizadas amostragens trimestrais pelo método da pesca elétrica em dois pontos de coleta, um próximo à nascente e outro nas proximidades da foz. As coletas resultaram na captura de 7.026 exemplares pertencentes a 12 espécies distribuídas em sete famílias. A nascente apresentou uma alta densidade em número de indivíduos e menores valores de diversidade, eqüitabilidade e riqueza de espécies em relação à foz. O levantamento da composição específica e abundância da ictiofauna de um rio é de grande importância, por fornecer subsídio a futuros manejos e monitoramentos, tanto da comunidade aquática quanto do ambiente.The composition and structure of fish community can be considered ecological and environmental indicators. The present study aimed to survey information about the specific composition and abundance of the ichthyofauna from Padres’ River. Quarterly samplings were accomplished by the method of the electrofishing in two sample sites, one close to the headwater and another in the proximities of the mouth. The collections resulted in the capture of 7026 specimens belonging to 12 species, which, in turn, fit in seven different families. The headwater presented a high density in number of individuals and smaller values of diversity, evenness and richness of species in relation to the mouth. The raising of the specific composition and abundance of the ichthyofauna of a river is of great importance for supplying subsidy to future managements and accompaniment, as much of the aquatic community as of the environment.

  3. $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with radioactive At beams

    CERN Multimedia

    We propose to study the $\\beta$-delayed fission, laser spectroscopy and radioactive decay of the newly available pure beams of neutron-deficient and neutron-rich astatine (Z=85) isotopes. The fission probability and the fission fragment distribution of the even-even isotopes $^{194,196}$Po following the $\\beta$-decay of the isotopes $^{194,196}$At will be studied with the Windmill setup. In-source laser spectroscopy will be performed on the entire astatine isotopic chain, using a combination of the Windmill setup, ISOLTRAP MR-ToF and ISOLDE Faraday. Radioactive decay data will be acquired at the Windmill setup throughout those studies and contribute to the global understanding of the phenomenon of shape coexistence in the neutron-deficient lead region.

  4. Sp ectroscopy of Low-lying States in Odd-Z Odd-A Nuclei Beyond Lead

    Institute of Scientific and Technical Information of China (English)

    U Jakobsson; S Juutinen; A Herzan; J Konki; M Leino; M Mallaburn; J Pakarinen; P Papadakis; J Partanen; P Rahkila; M Sandzelius; J Uusitalo; J Saren; C Scholey; J Sorri; S Stolze; K Auranen; H Badran; B Cederwall; D M Cox; T Grahn; P T Greenlees; R Julin

    2016-01-01

    Low-lying states in odd-Z odd-mass nuclei at the proton drip-line beyond lead have recently been studied through fusion-evaporation reactions using a gas-filled recoil separator. Isomeric 1/2+ and 13/2+ states have been observed in odd-mass astatine and francium nuclei. The systematic behaviour of the level energies of these states have been studied and a similarity between the 1/2+ state in astatine and francium has been found. Furthermore, the 13/2+ state has been observed in the francium nuclei with an oblate behaviour suggesting a coupling of the i13/2 proton to the 2p−2h intruder excitation.

  5. Two-component relativistic density-functional calculations of the dimers of the halogens from bromine through element 117 using effective core potential and all-electron methods.

    Science.gov (United States)

    Mitin, Alexander V; van Wüllen, Christoph

    2006-02-14

    A two-component quasirelativistic Hamiltonian based on spin-dependent effective core potentials is used to calculate ionization energies and electron affinities of the heavy halogen atom bromine through the superheavy element 117 (eka-astatine) as well as spectroscopic constants of the homonuclear dimers of these atoms. We describe a two-component Hartree-Fock and density-functional program that treats spin-orbit coupling self-consistently within the orbital optimization procedure. A comparison with results from high-order Douglas-Kroll calculations--for the superheavy systems also with zeroth-order regular approximation and four-component Dirac results--demonstrates the validity of the pseudopotential approximation. The density-functional (but not the Hartree-Fock) results show very satisfactory agreement with theoretical coupled cluster as well as experimental data where available, such that the theoretical results can serve as an estimate for the hitherto unknown properties of astatine, element 117, and their dimers.

  6. Gclust Server: 121686 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 121686 ATH_AT3G23380_15229436 Cluster Sequences Related Sequences(19) 193 RIC5 (ROP-INTERACTIVE...s Related Sequences(19) Sequence length 193 Representative annotation RIC5 (ROP-INTERACTIVE

  7. Dicty_cDB: Contig-U13016-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tntgntg 72 Query: 73 atttngatccnaaaccnttcntttgtaaaactgcngctgntgtttcngttggngttgctg 132 ||||||||||||||||||||||...|||||||||||||||||||||||||||||||||||||| Sbjct: 73 atttngatccnaaaccnttcntttgtaaaactgcngctgntgtttcngttggngttgct...gtntttatttttgnnggnaanaaag 192 Query: 193 gttatgacttntggaaancnagtcaaggngntncnatggccccntcnaatgccnatcccc 252 ||...|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 193 gttatgacttntggaaancnagtcaaggngntncnatggccccntcnaatgccna...e-30 Identities = 165/186 (88%) Strand = Plus / Plus Query: 71 tgatttngatccnaaaccnttcntttgtaaaactgcngctgntgt

  8. Dicty_cDB: Contig-U13557-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ntgccnttacatttggtgttcaantaaaanttcantggaaanaa 192 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||...| Sbjct: 133 attgtaantccgttngntgccnttacatttggtgttcaantaaaanttcantggaaanaa 192 Que...tngntgccnttacatttggtgttcaantaaaanttcantggaaanaan 193 |||||||||||||||||||||||||||||||||||||||||||||||||||||||...||||| Sbjct: 367 ttgtaantccgttngntgccnttacatttggtgttcaantaaaanttcantggaaanaan 308

  9. Research on Unintentional Injuries and Its Affecting Factors in Preschool Children at Urban Area of Guiyang City%贵阳市城区2 193例学龄前儿童意外伤害及影响因素的研究

    Institute of Scientific and Technical Information of China (English)

    刘玲; 刘筱娴; 文秋生; 王鸿娟; 李建芬; 鲁永辉

    2001-01-01

    【 Objective】 To find out the situation and influencing factors of unintentional injuries among preschool children at urban area in Guiyang city. 【Methods】 The descriptive epidemiology and case- control study was conducted among these chil drenin15kindergartens in Guiyang during1,April,98-31,Mar,99. 【Results】 The rate of injury was 24.76% with the boys ' higher than that of girls' (P < 0.05)and it rose very significanty with the chidren' s age went up.(P < 0.05) .The first threetypes of injuries were fall,collision and animal injuries.96.32% of injuries were mild and 3.68% were moderate. There was no disability and death. The analysis of single and multiple factors showed that the chileren' s unintentional injury were affected by following factors:fa ther' s age, the background of partent' s education, mother' s occupation, family pets, children' s nationality, persons taking care of chil dren, living floors and family average income. 【Conclusions】 The rate of children' s unintentional injury in Guiyang was high. The unintentionall injury was assoiated with many factors. It was a serious problem for Guiyang children.%【目的】了解贵阳市城区学龄前儿童意外伤害现况和影响因素。【方法】采用描述性流行病学和病例一对照研究的方法,对贵阳性市城区15所幼儿园的学龄前儿童在1998年4月1日~1999年3月31日期间发生的意外伤害情况和影响因素进行了研究。【结果】贵阳市城区学龄前儿童意外伤害发生率为24.76%,男童高于女童(P<0.05),意外伤害发生率随年龄增长而上升(P<0.05)。伤害类型前三位为:跌伤、撞伤、动物伤;96.32%的伤害为轻度,3.68%为中度,无1例伤残和死亡。单因素和多因素回归分析表明儿童意外伤害的发生受下列因素的影响:父亲年龄、父母文化程度、母亲职业、家庭宠物、儿童民族、儿童看护人、居住楼层、家庭人均收入等。【结论】贵阳市学龄前儿童意外伤害发生率高,意外伤害的发生受多种因素的影响,意外伤害是贵阳市儿童健康不可忽视的问题。

  10. Dicty_cDB: [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFC193 (Link to dictyBase) - - - Contig-U16382-1 VFC193P (Link... to Original site) VFC193F 338 VFC193Z 430 VFC193P 768 - - Show VFC193 Library VF (Link to library) Clone ID VFC193 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16382-1 Original site URL http://dict...producing significant alignments: (bits) Value N AC116957 |AC116957.2 Dictyostelium discoideum chromosome 2 ...map 1685067-2090751 strain AX4, complete sequence. 654 0.0 7 X03281 |X03281.1 Dict

  11. Alpha-decay studies of the new isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At

    CERN Document Server

    Kettunen, H; Grahn, T; Greenlees, P T; Jones, P; Julin, R; Juutinen, S; Keenan, A; Kuusiniemi, P; Leino, M; Leppaenen, A P; Nieminen, P; Pakarinen, J; Rahkila, P; Uusitalo, J

    2003-01-01

    Detailed alpha-decay studies have been performed for the neutron-deficient isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At. The nuclei were produced in fusion-evaporation reactions of sup 5 sup 4 Fe and sup 5 sup 6 Fe ions with a sup 1 sup 4 sup 1 Pr target. The fusion products were separated in-flight using a gas-filled recoil separator and implanted into a position-sensitive silicon detector. The isotopes were identified using position, time and energy correlations between the implants and subsequent alpha-decays. Three alpha-decaying states were identified for sup 1 sup 9 sup 3 At and two for sup 1 sup 9 sup 1 At. The spin and parity of the initial states in the astatine isotopes were deduced based on unhindered alpha-decays to states in the bismuth daughter nuclei. In both astatine isotopes the 1/2 sup + intruder state was determined to be the ground state and a 7/2 sup - state to be the first-excited state. In sup 1 sup 9 sup 3 At the alpha-decay of the 13/2 sup + state was observed in coincidence...

  12. EST Table: BP127127 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BP127127 tesS0033 10/09/28 100 %/193 aa ref|NP_001093079.1| beta-tubulin [Bombyx mo...13326418:-1|gene:AGAP010929 10/09/10 89 %/193 aa gnl|Amel|GB13049-PA 10/09/10 89 %/193 aa gi|171464762|gb|ACB45871.1| tublin [Tribolium castaneum] BP128081 tesS ...

  13. New supersymmetric quartet of nuclei in the A=190 mass region

    CERN Document Server

    Barea, J; Frank, A; Graw, G; Hertenberger, R; Wirth, H F; Christen, S; Jolie, J; Tonev, D; Balodis, M; Berzins, J; Kramere, N; Von Egidy, T

    2008-01-01

    We present evidence for a new supersymmetric quartet in the A=190 region of the nuclear mass table. New experimental information on transfer and neutron capture reactions to the odd-odd nucleaus 194 Ir strongly suggests the existence of a new supersymmetric quartet, consisting of the 192,193 Os and 193,194 Ir nuclei. We make explicit predictions for the odd-neutron nucleus 193 Os, and suggest that its spectroscopic properties be measured in dedicated experiments.

  14. Local Purchasing of Journals is Required in Addition to a Nationally Purchased Collection to Meet the Information Needs of NHS Staff. A review of: Glover, Steven William, John Addison, Colette Gleghorn, and John Bramwell. “Journal Usage in NHS Hospitals: A Comparison Report of Total Usage at an Acute NHS Trust and a Specialist NHS Trust in the North West of England.” Health Information and Libraries Journal 24.3 (2007: 193‐9.

    Directory of Open Access Journals (Sweden)

    Jennie Kelson

    2008-03-01

    Full Text Available Objective ‐ To compare journal usage between an acute National Health Service (NHS Trust and a specialist NHS Trust located in North West England to provide some evidence as to how well the National Core Content Collection (provided by ProQuest meets the needs of staff in these settings.Design ‐ Comparative studySetting ‐ An acute NHS Trust, comprising four hospital sites, and a cancer specialist NHS Trust based on a single site. Both Trusts are located in North West England. The cancer specialist NHS Trust is a teaching hospital with undergraduate nurses, medical students, and student radiographers. This Trust is also closely associated with an adjoining cancer research institute. The acute NHS Trust has a large number of healthcare staff in training and was not described as a teaching hospital.Subjects ‐ Staff of the respective NHS Trusts. The staff numbers for each organisation were not provided.Methods ‐ COUNTER usage statistics of online journals, obtained from publisher administration tools, were collected for one year covering the period 1 December 2005 to 30 November 2006. Where available, the number of photocopies made from print journals during the same period by library users for their own use was also included. All full‐text downloads of journal articles were counted as part of this study, hence the possibility of double counting if a single article was requested in both HTML and PDF versions. Details of free or open access articles accessed without the need for a username and password were not included in the study. To encourage use of the electronic journals, library services at both Trusts implemented a number of initiatives to maximize publicity. These included direct e‐mails to staff, posters, and presentations to staff. Athens registration, required for access to the electronic journal collections, was promoted as part of the induction process for new library users. Staff members were encouraged to apply for the electronic table of contents alert for journals in their area of specialty. An A‐Z list of journals was accessible via the Trusts’ intranet and internet sites, and direct links to electronic journals were added to the NHS Dialog/Datastar databases and on PubMed.Main results ‐ The libraries at both Trusts in the study provide the majority of their journals in electronic‐only format. In addition to the National Core Content titles, the cancer specialist Trust provides access to an additional five journal collections: Science Direct Health Sciences, Blackwell Synergy Medical and Nursing collection, five journals selected from Nature Publishing Group, selected society journals via HighWire Press and Oxford University Press titles. Staff members of the acute Trust have access to an additional three journal collections: Science Direct Health Sciences, the BMJ Publishing Group (BMJPG collection and 16 LWW titles via Ovid. During the study period, a total of 93,376 articles were downloaded or copied. Of these, 47,079 articles were downloaded or copied by staff of the cancer specialist NHS Trust and 46,297 articles were downloaded or copied by staff of the acute NHS Trust. The usage of each of the journal collections during the study period for each Trust is shown in the table below with the most used resource shown in bold. (See article for table General information regarding some of the commonly used journal titles by staff of each Trust was included in the commentary, but levels of use were not enumerated. Staff of the cancer specialist NHS Trust favoured cancer‐related titles, whilst staff of the acute NHS Trust accessed journal titles over a greater range of subject areas. Details of the top titles accessed from the National Core Content collection were not provided for either Trust. A possible reason given for the lower usage level of the National Core Content collection by the cancer specialist NHS Trust compared to the acute NHS Trust was the presence of embargoes on many cancer‐related titles within the National Core Content collection. Information about training offered to staff, their level of access to computer facilities,or familiarity with accessing electronic journal collections was not provided.Conclusion ‐ Staff of both Trusts in the study recorded a high level of journal use, with a total of 93,376 articles downloaded or photocopied during the study period. There was a marked difference in the usage patterns of the National Core Content journals between the two Trusts studied with the acute NHS Trust showing a higher proportion of usage (29.9%compared with the cancer specialist Trust(4.5%. Staff members of the acute NHS Trust accessed a greater range of subject areas, while staff those at the cancer specialist NHS Trust favoured cancer related titles.The results indicated that the National Core Content collection did not meet the information needs of the specialist cancer Trust as well as it met the needs of the more generalist acute Trust. The National Core Content collection appears insufficient to meet the diverse information needs of all NHS staff. Local purchasing of journals, in addition to national level provision, is therefore required to ensure that the needs of local specialties are adequately supported.

  15. Is electronegativity a useful descriptor for the pseudo-alkali metal NH4?

    Science.gov (United States)

    Whiteside, Alexander; Xantheas, Sotiris S; Gutowski, Maciej

    2011-11-18

    Molecular ions in the form of "pseudo-atoms" are common structural motifs in chemistry, with properties that are transferrable between different compounds. We have determined one such property--the electronegativity--for the "pseudo-alkali metal" ammonium (NH(4)), and evaluated its reliability as a descriptor versus the electronegativities of the alkali metals. The computed properties of ammonium's binary complexes with astatine and of selected borohydrides confirm the similarity of NH(4) to the alkali metal atoms, although the electronegativity of NH(4) is relatively large in comparison to its cationic radius. We have paid particular attention to the molecular properties of ammonium (angular anisotropy, geometric relaxation and reactivity), which can cause deviations from the behaviour expected of a conceptual "true alkali metal" with this electronegativity. These deviations allow for the discrimination of effects associated with the molecular nature of NH(4).

  16. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    CERN Document Server

    Marsh, B A; Imai, N; Seliverstov, M D; Rothe, S; Sels, S; Capponi, L; Rossel, R E; Franchoo, S; Wendt, K; Focker, G J; Kalaninova, Z; Sjoedin, A M; Popescu, L; Nicol, T; Huyse, M; Radulov, D; Atanasov, D; Kesteloot, N; Borgmann, Ch; Cocolios, T E; Lecesne, N; Ghys, L; Pauwels, D; Rapisarda, E; Kreim, S; Liberati, V; Wolf, R N; Andel, B; Schweikhard, L; Lane, J; Derkx, X; Kudryavtsev, Yu; Zemlyanoy, S G; Fedosseev, V N; Lynch, K M; Rosenbusch, M; Van Duppen, P; Lunney, D; Manea, V; Barzakh, A E; Andreyev, A N; Truesdale, V; Flanagan, K T; Molkanov, P L; Koester, U; Van Beveren, C; Wienholtz, F; Goodacre, T Day; Antalic, S; Bastin, B; De Witte, H; Fink, D A; Fedorov, D V

    2013-01-01

    At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar fr...

  17. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, B.A., E-mail: bruce.marsh@cern.ch [CERN, CH-1211 Geneva (Switzerland); Andel, B. [Comenius University, Bratislava (Slovakia); Andreyev, A.N. [University of York, Department of Physics, York YO10 5DD (United Kingdom); Antalic, S. [Comenius University, Bratislava (Slovakia); Atanasov, D. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Barzakh, A.E. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Bastin, B. [Grand Accérateur National d’Ions Lourds (GANIL), Bd Henri Becquerel, F-14076 Caen (France); Borgmann, Ch. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Capponi, L. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Cocolios, T.E.; Day Goodacre, T. [CERN, CH-1211 Geneva (Switzerland); University of Manchester, Manchester (United Kingdom); Dehairs, M. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Derkx, X. [University of the West of Scotland, School of Engineering, Paisley PA1 2BE (United Kingdom); De Witte, H. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fedorov, D.V. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Fedosseev, V.N.; Focker, G.J. [CERN, CH-1211 Geneva (Switzerland); Fink, D.A. [Ruprecht-Karls Universität, Seminarstr. 2, 69117 Heidelberg (Germany); CERN, CH-1211 Geneva (Switzerland); Flanagan, K.T. [University of Manchester, Manchester (United Kingdom); Franchoo, S. [CSNSM-IN2P3-CNRS, Université Paris-Sud, 91406 Orsay (France); and others

    2013-12-15

    Highlights: • Upgrade of the lasers, detectors and data acquisition for in-source resonance ionization spectroscopy at ISOLDE. • First use of the ISOLTRAP MR-ToF MS in combination with laser spectroscopy at ISOLDE. • Resonance ionization of astatine for the study of its nuclear structure. -- Abstract: At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar free ionization using the Laser Ion Source Trap, LIST (Po); isobar selective particle identification using the multi-reflection time-of-flight mass separator (MR-ToF MS) of ISOLTRAP (Au, At). These are summarized as part of an overview of the current status of the in-source resonance ionization spectroscopy setup at ISOLDE.

  18. Gclust Server: 164265 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 164265 HSA_62240997 Cluster Sequences - 193 NP_000790.2 erythropoietin precursor ; ...opoietin precursor ; no annotation Number of Sequences 1...k to cluster sequences Cluster Sequences Link to related sequences - Sequence length 193 Representative annotation NP_000790.2 erythr

  19. Assessing the Effects of Individual Augmentation (IA) on Active Component Navy Enlisted and Officer Retention

    Science.gov (United States)

    2008-08-01

    who deployed to Iraq and Afghanistan, it further increased to 1.93. exp(0.426) 1.53= exp(0.659) 1.93= 22 23 Term Estimate Std Error ChiSquare ...comparing all enlisted IAers versus all other Navy enlisted with deployment experience. 24 Term Estimate Std Error ChiSquare Prob>ChiSq Intercept

  20. 76 FR 17426 - Agency Information Collection Activities: Application for Waiver of Passport and/or Visa (Form I...

    Science.gov (United States)

    2011-03-29

    ... Waiver of Passport and/or Visa (Form I-193) AGENCY: U.S. Customs and Border Protection (CBP), Department... collection requirement concerning the Application for Waiver of Passport and/or Visa (Form I-193). This...: Title: Application for Waiver of Passport and/or Visa. OMB Number: 1651-0107. Form Number: CBP Form...

  1. A text in Romani from 1622

    DEFF Research Database (Denmark)

    Bakker, Peter

    2015-01-01

    this is a reprint of a 2012 article: A new old text in Romani: Lord's Prayer, 1622. International Journal of Romani Language and Culture 2 (2011): 193-212.......this is a reprint of a 2012 article: A new old text in Romani: Lord's Prayer, 1622. International Journal of Romani Language and Culture 2 (2011): 193-212....

  2. Northeast Asia Nuclear Dilemmas

    Science.gov (United States)

    2012-02-01

    Post-Vietnam Realities, edited by John P. Lovell and Phillip S. Kronenberg , (New Brunswick, NJ: Transaction Books, 1974), 193-228. 53 Derived...Relations: The Agonies of Post-Vietnam Realities, edited by John P. Lovell and Phillip S. Kronenberg . New Brunswick, NJ: Transaction Books, 1974, 193-228

  3. Ametniku mõiste avaliku teenistuse seaduse eelnõus / Ebe Sarapuu

    Index Scriptorium Estoniae

    Sarapuu, Ebe

    2012-01-01

    Ametniku mõistest 1924. aastal vastu võetud riigiteenistuse seaduses, 1995. aastal vastu võetud avaliku teenistuse seaduses ja 2002. (964 SE), 2009. (484 SE ja 538 SE) ja 2012. aasta avaliku teenistuse seaduse (193 SE) eelnõus. Muudatustest uues seaduseelnõus (193 SE)

  4. Electron Density and Temperature During the CHARGE-2B Sounding Rocket Mission

    Science.gov (United States)

    1997-07-01

    instrument. 13 Horowitz, P., and Hill, W. (1989) The Art of Electronics , Cambridge University Press, New York, pp 192-193. 18 -5 c £ V. 3 ü ■ö...Res., 86:575-584. 13. Horowitz, P., and Hill, W. (1989) The Art of Electronics , Cambridge University Press, New York, pp 192-193. 21 14

  5. Intense predation on ascidians by a trunk fish, Ostracion immaculatus (Temminck et Schlege) (Pisces:Ostracidae)

    Digital Repository Service at National Institute of Oceanography (India)

    Raveendran, T.V; Harada, E.

    stream_size 9 stream_content_type text/plain stream_name Publ_Seto_Mar_Biol_Lab_37_193.pdf.txt stream_source_info Publ_Seto_Mar_Biol_Lab_37_193.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  6. NCBI nr-aa BLAST: CBRC-LAFR-01-1256 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-LAFR-01-1256 ref|ZP_01056432.1| cobalamin 5'-phosphate synthase [Roseobacter s...p. MED193] gb|EAQ45647.1| cobalamin 5'-phosphate synthase [Roseobacter sp. MED193] ZP_01056432.1 1.00 32% ...

  7. NCBI nr-aa BLAST: CBRC-DYAK-03-0005 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-DYAK-03-0005 ref|ZP_01058288.1| copper-translocating P-type ATPase [Roseobacte...r sp. MED193] gb|EAQ43820.1| copper-translocating P-type ATPase [Roseobacter sp. MED193] ZP_01058288.1 0.092 25% ...

  8. NCBI nr-aa BLAST: CBRC-CJAC-01-1298 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CJAC-01-1298 ref|ZP_01054714.1| type I secretion target repeat protein [Roseob...acter sp. MED193] gb|EAQ47205.1| type I secretion target repeat protein [Roseobacter sp. MED193] ZP_01054714.1 5e-17 40% ...

  9. NCBI nr-aa BLAST: CBRC-OPRI-01-1553 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-OPRI-01-1553 ref|ZP_01057726.1| Holliday junction DNA helicase RuvA [Roseobact...er sp. MED193] gb|EAQ44205.1| Holliday junction DNA helicase RuvA [Roseobacter sp. MED193] ZP_01057726.1 1.4 34% ...

  10. Cloud Point Extraction of Parabens Using Non-Ionic Surfactant with Cylodextrin Functionalized Ionic Liquid as a Modifier

    Directory of Open Access Journals (Sweden)

    Md Saleh Noorashikin

    2013-12-01

    Full Text Available A cloud point extraction (CPE process using non-ionic surfactant (DC193C to extract selected paraben compounds from water samples was investigated using reversed phase high performance liquid chromatography (RP-HPLC. The CPE process with the presence of β-cyclodextrin (βCD functionalized ionic liquid as a modifier (CPE-DC193C-βCD-IL is a new extraction technique that has been applied on the optimization of parameters, i.e., pH, βCD-IL concentration and phase volume ratio. This CPE-DC193C-βCD-IL method is facilitated at 30 °C, showing great losses of water content in the surfactant-rich phase, resulting in a high pre-concentration factor and high distribution coefficient. The developed method CPE-DC193C-βCD-IL did show enhanced properties compared to the CPE method without the modifier (CPE-DC193C. The developed method of CPE-DC193C-βCD-IL gives an excellent performance on the detection of parabens from water samples with the limit of detection falling in the range of 0.013–0.038 µg mL−1. Finally, the inclusion complex formation, hydrogen bonding, and π–π interaction between the βCD-IL, benzyl paraben (ArP, and DC 193C were proven using 1H NMR and 2D NOESY spectroscopy.

  11. Cloud point extraction of parabens using non-ionic surfactant with cylodextrin functionalized ionic liquid as a modifier.

    Science.gov (United States)

    Noorashikin, Md Saleh; Raoov, Muggundha; Mohamad, Sharifah; Abas, Mhd Radzi

    2013-12-17

    A cloud point extraction (CPE) process using non-ionic surfactant (DC193C) to extract selected paraben compounds from water samples was investigated using reversed phase high performance liquid chromatography (RP-HPLC). The CPE process with the presence of β-cyclodextrin (βCD) functionalized ionic liquid as a modifier (CPE-DC193C-βCD-IL) is a new extraction technique that has been applied on the optimization of parameters, i.e., pH, βCD-IL concentration and phase volume ratio. This CPE-DC193C-βCD-IL method is facilitated at 30 °C, showing great losses of water content in the surfactant-rich phase, resulting in a high pre-concentration factor and high distribution coefficient. The developed method CPE-DC193C-βCD-IL did show enhanced properties compared to the CPE method without the modifier (CPE-DC193C). The developed method of CPE-DC193C-βCD-IL gives an excellent performance on the detection of parabens from water samples with the limit of detection falling in the range of 0.013-0.038 µg mL-1. Finally, the inclusion complex formation, hydrogen bonding, and π-π interaction between the βCD-IL, benzyl paraben (ArP), and DC 193C were proven using 1H NMR and 2D NOESY spectroscopy.

  12. HIV and the internally displaced: Burundi in focus

    Directory of Open Access Journals (Sweden)

    Raquel Wexler

    2003-01-01

    Full Text Available "Special attention should also be given to the prevention of contagious and infectious diseases, including AIDS, among internally displaced persons." (Guiding Principles on InternalDisplacement, 19.3

  13. 1984 walrus harvest, health, and welfare study at Gambell, Alaska: Progress report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The recorded harvest between 25 April and 8 June in Gambell was 1499 walruses. There were 373 adult males, 528 adult females, 405 calves, and 193 of unknown sex....

  14. Dicty_cDB: Contig-U01567-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ttcatnggaatcattccatttaaaagtttaaagggtaaaggtttattatta 199 Query: 200 tttcantatggggg...aattcaatanggttttttangtcccctaaggt 245 |||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 200 tttcantatgggg... Query: 149 ttcatnggaatcattccatttaaaagtttaaagggtaaaggtttattattatttcantat 208 ||||...atcattccatctaaaattttaaatnataaagtttt 701 Query: 193 attattatttcantatg 209 |||||||| ||| |||| Sbjct: 702 attatt...aatcattccatttaaaagtttaaagggtaaa 187 Query: 188 ggtttattattatttcantatgggggaattcaatanggttttttangtcccctaaggt 24

  15. Moose Survey-Inventory Progress Report : Unit 15A Kenai

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes the 1972 moose surveys on Kenai National Wildlife Refuge, Game Management Unit 15(A). Harvest report returns indicate a hunter harvest of 193...

  16. Alaska Federal Oil and Gas Historical Leases

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains the outlines for historic (i.e., relinquished or inactive) federal oil and gas leases in the Alaska OCS Region through sale 193. They...

  17. Disease: H00407 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 4 C564336 OMIM: 264470 261515 614307 214950 607748 233400 PMID:17347916 Shimozawa N Molecular and clinical a...spects of peroxisomal diseases. J Inherit Metab Dis 30:193-7 (2007) PMID:16376506 Funato M, Shimozawa

  18. Addiction in developmental perspective: influence of conduct disorder severity, subtype, and attention-deficit hyperactivity disorder on problem severity and comorbidity in adults with opioid dependence.

    NARCIS (Netherlands)

    Carpentier, P.J.; Knapen, L.J.; Gogh, M.T. van; Buitelaar, J.K.; Jong, C.A.J. de

    2012-01-01

    This retrospective cross-sectional study examines whether conduct disorder and attention deficit hyperactivity disorder are associated with problem severity and psychiatric comorbidity in 193 middle-aged, opioid-dependent patients. Conduct disorder history, attention deficit hyperactivity disorder,

  19. Low Noise Millimeter Wave LNA Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Phase I effort will result in a low noise MMIC G-Band amplifier the covers the entire 165 to 193GHz frequency range. The amplifier will be designed using a 50nm...

  20. EnviroAtlas - Durham, NC - BenMAP Results by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset demonstrates the effect of changes in pollution concentration on local populations in 193 block groups in Durham, North Carolina. The US...

  1. EST Table: FS748350 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available PREDICTED: similar to fetal alzheimer antigen, falz [Nasonia vitripennis] 10/09/08 37 %/193 aa FBpp0290563|E...811424.1| PREDICTED: similar to fetal alzheimer antigen, falz [Tribolium castaneum] FS748350 caL- ...

  2. Integrated circuit reliability. Citations from the NTIS data base

    Science.gov (United States)

    Reed, W. E.

    1980-06-01

    The bibliography presents research pertinent to design, reliability prediction, failure and malfunction, processing techniques, and radiation damage. This updated bibliography contains 193 abstracts, 17 of which are new entries to the previous edition.

  3. 78 FR 2912 - Prohibition on Personal Use of Electronic Devices on the Flight Deck

    Science.gov (United States)

    2013-01-15

    ... International Journal of Aviation Psychology, 19(3), 182-199 (2009). The ``party'' situation, when a person at a... report summarizing each substantive public contact with FAA personnel concerning this proposed...

  4. 77 FR 3324 - Release of Airport Property: Fort Myers International Airport, Fort Myers, FL

    Science.gov (United States)

    2012-01-23

    ... property is located north of Daniels Parkway and Chana Court, near the intersection of Chamberlin Parkway... Interstate 75. Lee County will also transfer ownership of 1.93 acres of property north of Daniels Parkway...

  5. An enantioselective formal synthesis of (-)-thujopsene

    Institute of Scientific and Technical Information of China (English)

    Chen Xi Zhang; Li Jing Fang; Fu Qiang Bi; Yu Lin Li

    2008-01-01

    Dihydromayurone (3), a key intermediate to synthesize (-)-thujopsene (1), was efficient enantiocontrolled synthesized from (+)-dihydrocarvone through 9 steps in an overall yield of 19.3%. The key step was the Simmons-Smith reaction.

  6. Digital data sets that describe aquifer characteristics of the Elk City aquifer in western Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized water-level elevation contours for the Elk City aquifer in western Oklahoma. The aquifer covers an area of approximately 193,000...

  7. Digital data sets that describe aquifer characteristics of the Elk City aquifer in western Oklahoma

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digitized aquifer boundaries for the Elk City aquifer in western Oklahoma. The aquifer covers an area of approximately 193,000 acres and...

  8. Interpretation of Biosphere Reserves.

    Science.gov (United States)

    Merriman, Tim

    1994-01-01

    Introduces the Man and the Biosphere Programme (MAB) to monitor the 193 biogeographical provinces of the Earth and the creation of biosphere reserves. Highlights the need for interpreters to become familiar or involved with MAB program activities. (LZ)

  9. Experiment list: SRX150405 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available mesoderm|Description=lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epst...193 || cell organism=human || cell description=lymphoblastoid, International HapMap Project, Yoruba in Ibada

  10. EnviroAtlas - Durham, NC - Ecosystem Services by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset presents environmental benefits of the urban forest in 193 block groups in Durham, North Carolina. Carbon attributes, temperature reduction,...

  11. 2. The Data Librarian: introducing the Data Librarian

    OpenAIRE

    1997-01-01

    This paper provides some initial considerations into the design and function of the Data Librarian. The first part (Liscouski, J., 1997, Journal of Automatic Chemistry, 19, 193-197) described the need for the Librarian.

  12. AK_Lease

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains the outlines for active federal oil and gas leases in the Alaska OCS Region through sale 193. They represent a close approximation, but might...

  13. WTO/TBT-SPS风险预警通报

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ TBT 美国发布无机溴化物容许量动议G/TBT/N/USA/193 据设在国家质检总局的中国WTO/TBT通报咨询中心消息:美国环保署(EPA)2006年6月2日发布了G/TBT/N/USA/193号通报.标题:无机溴化物容许量动议.

  14. Defining Stability, Security, Transition, and Reconstruction (SSTR) Operations Requirements for Future Department of the Navy Training and Analytical Models and Simulations

    Science.gov (United States)

    2008-09-01

    event 193 Rene Descartes (1960). Discourse on Method and Meditations. New York: The Liberal Arts Press...of State’s country website for Burma. Retrieved from http://www.state.gov/p/eap/ci/bm/. Descartes , Rene ; Laurence J. Lafleur (trans.) (1960...objects which in their own nature do not stand in a relation of antecedence and sequence. -- Rene Descartes193 A. INTRODUCTION Implementation of

  15. Trends in Navy Waste Reduction and Materials Markets.

    Science.gov (United States)

    1981-06-01

    su. - -e transient, It may not be poe - under pressure of carbonation. Cups and lower beverage prices for consumers. sible to use returnable containers...193 "Is Paper Industry Doomed by Electronic Publishing?" David R. Allan ,Pulp & Paper, October 1980. 194 "Steel Industry, USA: The Ubiquitous Electric...Paper Industry Doomed by Electronic Publishing?", by David R. Allan , News Editor, Pulp & Paper, October 1980. [193] ISIS Handbook. Institute of Scrap

  16. A large outbreak of human salmonellosis traced to a local pig farm.

    OpenAIRE

    Maguire, H. C.; Codd, A A; Mackay, V. E.; Rowe, B.; Mitchell, E

    1993-01-01

    An outbreak of Salmonella typhimurium definitive type (DT) 193 affecting 206 persons occurred in July and August 1989 in a small town in northern England. A descriptive study suggested that cold meats including pork from a butcher's shop in the town were vehicles of infection. An analytical study of a cohort attending a function in the town showed a significant association between illness and consumption of cold roast pork supplied by the butcher's shop (P = 0.00000004). S. typhimurium DT 193...

  17. Building for Peace: U.S. Army Engineers in Europe 1945-1991

    Science.gov (United States)

    2005-01-01

    the quality of work-the "how to" set out in American specifications- Germans turned to the Deutsche Industrie- Normen (DIN). The Germans had a DIN on...specifications, 193 Deutsche Bundesbauverwaltung (DBBV), 67, 121-23 Deutsche Industrie- Normen (DIN), 193 Deutschmark (OM) construction, 44, 51, 67...95-96,99,121-23,128,132,153,165,301 DIN. See Deutsche Industrie- Normen (DIN). Direct contracting system, 243, 246, 340-41 Directorate of

  18. ISO/TC33 Meeting Held in Salvador,Brasil,October 2009

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ ISO/TC33 Meeting was held in Salvador Brasil on 12-13 October 2009.Delegates from UK,USA,Germany,Australia,Japan and China attended the meeting.Two Chinese delegates,the new chairman of ISO/TC33 Li Hongxia fthe committee chaiman of SAC/TC193 and the president of Sinosteel Luoyang Institute of Refractories Research Co.,Ltd.)and Zhang Yongfhng(vice general secretary of SAC/TC193),were present.

  19. An Approach to the 40-Year Drug War

    Science.gov (United States)

    2012-05-17

    do smuggle large sums of cash back across the border, but prefer a process called Black Market Peso Exchange (BMPE).189 BMPE is a system in which...Mexican Institute, 170. 192 Ibid., 189. 193 Ibid., 193. The El Paso corridor runs from El Paso, Texas to Ciudad Juarez. The Tucson Corridor runs from...in a market –sharing 223 Culp, “Military Counter Drug Operations,” 5.; Brad Freden, “The

  20. Drug: D02206 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available pocytokine signaling pathway map07051 Antidiabetics Therapeutic category of drugs in Japan [BR:br08301] 3 Ag...ents affecting metabolism 39 Other agents affecting metabolism 396 Antidiabetic agents 3962 Biguanides D0220...D02206 Drug Buformin hydrochloride (JP16); Dibetos-B (TN) C6H15N5. HCl 193.1094 193.6777 D02206.gif Antidiab...etic [DS:H00409] Therapeutic category: 3962 ATC code: A10BA03 biguanides AMPK activ

  1. Domain Modeling: NP_005431.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_005431.1 chr17 G proteins c2rgnf_ chr17/NP_005431.1/NP_005431.1_apo_7-193.pdb d1kmqa_ chr17/NP_005431.1.../NP_005431.1_holo_7-193.pdb blast 14G,15D,16A,17E,18C,19G,20K,21T,22A,23L,32Y,33P,36Y

  2. Isolation and characterization of a novel thermostable neopullulanase-like enzyme from a hot spring in Thailand.

    Science.gov (United States)

    Tang, Kittapong; Kobayashi, Rutchadaporn Sriprang; Champreda, Verawat; Eurwilaichitr, Lily; Tanapongpipat, Sutipa

    2008-06-01

    A gene encoding a thermostable pullulan-hydrolyzing enzyme was isolated from environmental genomic DNA extracted from soil sediments of Bor Khleung hot spring in Thailand. Sequence comparison with related enzymes suggested that the isolated enzyme, designated Env Npu193A, was most likely a neopullulanase-like enzyme. Env Npu193A was expressed in Pichia pastoris as a monomeric recombinant protein. The purified Env Npu193A exhibited pH stability ranging from 3 to 9. More than 60% of enzyme activity was retained after incubation at 60 degrees C for 1 h. Env Npu193A was found to hydrolyze various substrates, including pullulan, starch, and gamma-cyclodextrin. The optimal working condition for Env Npu193A was at pH 7 at 75 degrees C with K(m) and V(max) toward pullulan of 1.22+/-0.3% and 23.24+/-1.7 U/mg respectively. Env Npu193A exhibited distinct biochemical characteristics as compared with the previously isolated enzyme from the same source. Thus, a culture-independent approach with sequence-basing was found to be an effective way to discover novel enzymes displaying unique substrate specificity and high thermostability from natural bioresources.

  3. Value of color Doppler flow imaging on screening and diagnosis of vein thrombosis in perioperative patients with lower extremity fracture%彩色多普勒血流显像筛查下肢骨折围手术期静脉血栓的价值及意义

    Institute of Scientific and Technical Information of China (English)

    徐志强; 刘照宏; 李炎; 方耀忠; 梁峭嵘; 廖荣宗

    2011-01-01

    目的 观察CDFI筛查下肢骨折围手术期静脉血栓形成的价值及意义.方法 回顾性分析1077例下肢骨折围手术期CDFI检查资料,重点观察下肢静脉有无血栓形成,累及部位、范围、声像图表现及血管腔阻塞等情况.结果 1077例患者,发现静脉血栓193例,阳性率17.92%(193/1077);其中术前发现171例,术后发现22例;急性血栓127例(127/193,65.80%),慢性血栓41例(41/193,21.24%),混合期血栓25例(25/193,12.95%);多发152例,单发41例.94.49%(120/127)的急性血栓发生在髂外静脉至胫后、腓静脉上段水平,68.29%(28/41)的慢性血栓发生在小腿肌肉静脉丛;82.38%(159/193)血栓致静脉大部分或完全阻塞,17.62%(34/193)血栓致静脉小部分阻塞.所有患者均接受抗凝溶栓治疗、植入腔静脉滤网等治疗,1例发生肺栓塞,积极抢救后痊愈.结论 下肢骨折围手术期静脉血栓发生率较高.CDFI作为下肢骨折围手术期的常规检查项目非常必要,可为临床治疗提供重要参考依据.%Objective To ohserve the value of CDFI on screening and diagnosing vein thromhosis in perioperative patients with lower extremity fractured . Methods A total of 1077 patients with lower extremely f'racture were examined with CDFI . Whether vein thrombosis happened or not in lower extremity , the location , range , image of vein thromhosis , and the blood vessel cavity blockage were observed . Results Of 1077 patients , venous thrombosis were found in 193 , the positive rate was 17. 92% (193/1077) , including 171 in preoperation and 22 in postoperation . Acute vein thrombosis were detected in 127 patients (127/193 . 65. 80% ) . chronic vein thrombosis in 41 patients (41/193 . 21. 24% ) and mixed vein thrombosis in 25 patients (25/193 ,12. 95% ) . Multiple thrombosis were f'ound in 152 patients , and single thromhosis in 41 patients .Totally 94. 49% (120/127 ) cases of acute vein thrombosis happened in external iliac vein to posterior

  4. Development of Reagents for Application of At-211 to Targeted Radionuclide Therapy of Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D. Scott

    2011-12-23

    This grant covered only a period of 4 months as the major portion of the award was returned to DOE due to an award of funding from NIH that covered the same research objectives. A letter regarding the termination of the research is attached as the last page of the Final Report. The research conducted was limited due to the short period of this grant, but the results obtained in that period are outlined in the Final Report. The studies addressed in the research effort were directed at a problem that is of critical importance to the in vivo application of the alpha-particle emitting radionuclide At-211. That problem, low in vivo stability of many astatinated molecules, severely limits the use of At-211 in therapeutic applications. The advances sought in the studies were expected to expand the types of biomolecules that can be used as carriers of At-211, and provide improved in vivo targeting of the radiation dose compared with the dose delivered to normal tissue.

  5. Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with {sup 211}At-EGF

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, Aasa Liljegren; Orlova, Anna; Gedda, Lars; Tolmachev, Vladimir; Carlsson, Joergen [Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala (Sweden); Almqvist, Ylva [Division of Radiology, Uppsala University, Uppsala (Sweden); Blomquist, Erik [Division of Oncology, Uppsala University, Uppsala (Sweden); Jensen, Holger J. [Department of Clinical Physiology and Nuclear Medicine, PET and Cyclotron Unit, Rigshospitalet, Copenhagen (Denmark)

    2003-10-01

    The EGFR-TKI (epidermal growth factor receptor tyrosine kinase inhibitor) gefitinib ['Iressa' (trademark of the AstraZeneca group of companies), ZD1839] increases the cellular uptake of radiolabelled epidermal growth factor (EGF). We investigated gefitinib treatment combined with astatine-211 EGF targeting in vitro using two cell lines expressing high levels of EGFR: A431 (sensitive to gefitinib) and U343MGaCl2:1 (resistant to gefitinib). In both cell lines, the uptake of {sup 211}At-EGF was markedly increased by concomitant treatment with gefitinib. Survival was investigated using both a clonogenic survival assay and a cell growth assay. Combined gefitinib and {sup 211}At-EGF treatment reduced the survival of U343 cells 3.5-fold compared with {sup 211}At-EGF alone. In A431 cells, {sup 211}At-EGF treatment resulted in very low survival, but combined treatment with gefitinib increased the survival by about 20-fold. These results indicate that combined treatment with gefitinib might increase the effect of ligand-mediated radionuclide therapy in gefitinib-resistant tumours and decrease the effect of such therapy in gefitinib-sensitive tumours. (orig.)

  6. Effect of cetuximab in combination with alpha-radioimmunotherapy in cultured squamous cell carcinomas

    Energy Technology Data Exchange (ETDEWEB)

    Nestor, Marika, E-mail: marika.nestor@bms.uu.s [Unit of Otolaryngology and Head and Neck Surgery, Department of Surgical Sciences, Uppsala University, S-751 85 Uppsala (Sweden); Unit of Biomedical Radiation Sciences, Department of Oncology, Radiology and Clinical Immunology, Uppsala University, S-751 85 Uppsala (Sweden); Sundstroem, Magnus [Unit of Molecular Pathology, Department of Genetics and Pathology, Uppsala University (Sweden); Anniko, Matti [Unit of Otolaryngology and Head and Neck Surgery, Department of Surgical Sciences, Uppsala University, S-751 85 Uppsala (Sweden); Tolmachev, Vladimir [Unit of Biomedical Radiation Sciences, Department of Oncology, Radiology and Clinical Immunology, Uppsala University, S-751 85 Uppsala (Sweden)

    2011-01-15

    Aim: The monoclonal antibody cetuximab, targeting the epidermal growth factor receptor (EGFR), is a promising molecular targeting agent to be used in combination with radiation for anticancer therapy. In this study, effects of cetuximab in combination with alpha-emitting radioimmunotherapy (RIT) in a panel of cultured human squamous cell carcinomas (SCCs) were assessed. Methods: SCC cell lines were characterized and treated with cetuximab in combination with anti-CD44v6 RIT using the astatinated chimeric monoclonal antibody U36 ({sup 211}At-cMAb U36). Effects on {sup 211}At-cMAb U36 uptake, internalization and cell proliferation were then assessed in SCC cells. Results: Cetuximab in combination with {sup 211}At-cMAb U36 mediated increased growth inhibition compared to RIT or cetuximab alone in two cell lines. However, cetuximab also mediated radioprotective effects compared to RIT alone in two cell lines. The radioprotective effects occurred in the cell lines in which cetuximab clearly inhibited cell growth during radiation exposure. Cetuximab treatment also influenced {sup 211}At-cMAb-U36 uptake and internalization, suggesting interactions between CD44v6 and EGFR. Conclusions: Results from this study demonstrate the vast importance of further clarifying the mechanisms of cetuximab and radiation response, and the relationship between EGFR and suitable RIT targets. This is important not only in order to avoid potential radioprotective effects, but also in order to find and utilize potential synergistic effects from these combinations.

  7. Cyclotron production of cesium radionuclides as analogues for francium-221 biodistribution

    Science.gov (United States)

    Finn, R.; McDevitt, M.; Sheh, Y.; Lom, C.; Qiao, J.; Cai, S.; Burnazi, E.; Nacca, A.; Pillarsetty, N.; Jaggi, J.; Scheinberg, D.

    2005-12-01

    In our clinical investigations focussing on improved therapeutic treatment of specific tumors we have concentrated on a targeted therapy approach utilizing designed radiolabeled monoclonal antibodies as the cytotoxic reagent. The physical characteristics of the alpha particle emitting radionuclide bismuth-213 including the short half-life of 45.6 min, has shown promise for the treatment of specific cancers such as leukemias and lymphomas or micrometastatic carcinomas. In an effort to increase the cytocidal effect of the HuM195, a humanized monoclonal antibody carrier to the CD33 antigen expressed on leukemia cells, our focus is directed toward an "internal" nano-generator composed of Ac-225 radionuclide, the parent of the bismuth-213. The actinium-225 radionuclide decays through several short-lived, alpha emitting daughters including francium-221, astatine-217 and bismuth-213. In order to study the biodistribution and the pharmacokinetics of the individual daughter nuclide, francium-221, the cyclotron production and separation of cesium radionuclides, specifically cesium-132, from a natural xenon gas target was undertaken. The choice of cesium as an analogue for francium was predicated upon both elements being in Group 1A alkali metals and cesium radionuclide possesses a sufficient half-life to allow biodistribution studies to be performed. The preliminary experimental results of this investigation are presented.

  8. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  9. Study of Neutron-Deficient $^{202-205}$Fr Isotopes with Collinear Resonance Ionization Spectroscopy

    CERN Document Server

    De Schepper, Stijn; Cocolios, Thomas; Budincevic, Ivan

    The scope of this master’s thesis is the study of neutron-deficient $^{202−205}$Fr isotopes. These isotopes are inside the neutron-deficient lead region, a region that has shown evidence of shape coexistence. For this thesis, this discussion is limited to the phenomenon where a low lying excited state has a different shape than the ground state. Shape coexistence is caused by intruder states. These are single-particle Shell Model states that are perturbed in energy due to the interaction with a deformed core. In the neutron-deficient lead region the main proton intruder orbit is the 3s$_{1/2}$orbit. When going towards more neutron-deficient isotopes, deformation increases. The $\\pi3s_{1/2}$orbit will rise in energy and will eventually become the ground state in odd- A bismuth (Z=83) isotopes. It is also observed in odd-A astatine (Z=85) isotopes, already in less neutron-deficient nuclei. The same phenomenon is expected to be present francium (Z=87) isotopes already at $^{199}$Fr. Although it is currently ...

  10. Metalloids, soil chemistry and the environment.

    Science.gov (United States)

    Lombi, Enzo; Holm, Peter E

    2010-01-01

    This chapter reviews physical chemical properties, origin and use ofmetalloids and their relevance in the environment. The elements boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), tellurium (Te), polonium (Po) and astatine (At) are considered metalloids. Metalloids conduct heat and electricity intermediate between nonmetals and metals and they generally form oxides. The natural abundance ofmetalloids varies from Si being the second most common element in the Earth's crust to At as the rarest of natural elements on Earth. The metalloid elements Ge, Te, Po and At are normally present in trace or ultratrace levels in the environment and as such are not considered of relevance in terms of environmental health. The environmental geochemical processes, factors and parameters controlling the partitioning and the speciation of B, Si, As and Sb are reviewed in relation to the bioavailability of these metalloids. Approaches based on the hypothesis that metal toxicity is related to both the metal-ligand complexation processes and the metal interactions with competing cations at the cell surface (biotic ligand) have so far not been successful for assessing metalloid bioavailability. The chapter concludes that our understanding of metalloids toxicity will improve in the future if, in addition to the points discussed above, surface membrane potentials are considered. This should represent a robust approach to the prediction of metalloid toxicity.

  11. SPECT assay of radiolabeled monoclonal antibodies. Progress report, September 1, 1992--August 24, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1993-08-20

    The overall goal of this project is to improve the effectiveness of single photon emission computed tomography (SPECT) to image and quantify radiolabeled monoclonal antibodies. During the past year, we have made significant progress toward this goal, and this report summarizes that work. Our efforts have been mainly directed along three fronts. First, we have developed and tested new reconstruction methods including three-dimensional iterative algorithms that model non-uniform attenuation and distance-dependent detector response. Both fan beam and parallel beam collimator geometries have been modeled and novel ways of improving the efficiency of the computationally intensive methods have been introduced. Second, an ultra-high resolution, small field-of-view pinhole collimator has been constructed and evaluated. Reconstructed spatial resolution of 1 to 3 mm (FWHM) has been achieved in phantom scans with a useful field-of-view of 9 to 10 cm. Finally, we have investigated the ability of SPECT to image and quantify astatine-211 distributions. Reconstructed images of phantom data demonstrated quantitative accuracy to within 10% with proper attenuation and scatter compensation.

  12. Glomerular filtration rate after alpha-radioimmunotherapy with 211At-MX35-F(ab')2: a long-term study of renal function in nude mice

    DEFF Research Database (Denmark)

    Back, T.; Haraldsson, B.; Hultborn, R;

    2009-01-01

    and animals bearing subcutaneous xenografts of the human ovarian cancer cell line, OVCAR-3, were used. The animals received approximately 0.4, 0.8, or 1.2 MBq in one, two, or three fractions. The mean absorbed doses to the kidneys ranged from 1.5 to 15 Gy. The renal function was studied by serial GFR...... of the glomerular filtration rate (GFR). The renal toxicity was evaluated at levels close to the dose limit for the bone marrow and well within the range for therapeutic efficacy on tumors. Astatinated MX35-F(ab')(2) monoclonal antibodies were administered intravenously to nude mice. Both non-tumor-bearing animals...... manifested late. Examination of the kidney sections showed histologic changes that were overall subdued. Following alpha-RIT with (211)At-MX35-F(ab')(2) at levels close to the dose limit of severe myelotoxicity, the effects found on renal function were relatively small, with only minor to moderate reductions...

  13. Silver impregnated nanoparticles of titanium dioxide as carriers for {sup 211}At

    Energy Technology Data Exchange (ETDEWEB)

    Cedrowska, Edyta; Lyczko, Monika; Piotrowska, Agata; Bilewicz, Aleksander [Institute of Nuclear Chemistry and Technology, Warsaw (Poland); Stolarz, Anna; Trcinska, Agnieszka [Warsaw Univ. (Poland). Heavy Ion Lab.; Szkliniarz, Katarzyna [Silesia Univ. Katowice (Poland). Inst. of Physics; Was, Bogdan [Polish Academy of Science, Cracow (Poland). Inst. of Nuclear Physics

    2016-08-01

    The {sup 211}At radioisotope exhibits very attractive nuclear properties for application in radionuclide therapy. Unfortunately use of {sup 211}At is limited, because astatine as the heaviest halogen forms weak bond with carbon atoms in the biomolecules which makes {sup 211}At bioconjugates unstable in physiological conditions. In our work we propose a new solution for binding of {sup 211}At which consists of using nanoparticles of titanium dioxide modified with silver atoms as carriers for {sup 211}At. Ag{sup +} cations have been absorbed on the nanometer-sized TiO{sub 2} particles (15 and 32 nm) through ion exchange process and were reduced in Tollens' reaction. The obtained TiO{sub 2}-Ag nanoparticles were labeled with {sup 211}At. It was found that labeling yields were almost quantitative under reducing conditions, while under oxidizing conditions they dropped to about 80%. The labeled nanoparticles exhibited very high stability in physiological salt, PBS buffer, solutions of peptides (0.001 M cysteine, 0.001 M glutathione) and in human blood serum. To make TiO{sub 2}/Ag nanoparticles well dispersed in water and biocompatible their surface was modified with a silane coupling agent containing poly(ethyleneglycol) molecules. The developed functionalization approach will allow us to attach biomolecules to the TiO{sub 2}/Ag surface.

  14. Studies of Stable Octupole Deformations in the Radium Region

    CERN Multimedia

    2002-01-01

    The purpose of the present project is to locate and identify states in the atomic nuclei possessing stable pearshaped octupole deformation. Such states, formally related to the structures known in molecular physics, manifest themselves as families of parity doublets in odd nuclei.\\\\ \\\\ The best possibilities for observing stable octupole deformations are offered in the Ra-region. Both theoretical calculations and experimental indications support such expectations. Such indications are the non-observation of two-phonon octupole vibrational states in the ISOLDE studies of the even-even radium nuclei, and the reversed sign of the decoupling factor of the ground state band in |2|2|5Ra observed in the single-neutron transfer reactions. In order to establish the predicted strong E1 and E3-transitions between the parity doublets in odd nuclei with stable octupole deformations it is proposed to study conversion electrons in odd-mass francium radium and radon isotopes following the @b-decay of francium and astatine. \\...

  15. Alpha particle emitters in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R.

    1989-09-01

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

  16. Stathmin 1 is a potential novel oncogene in melanoma.

    Science.gov (United States)

    Chen, J; Abi-Daoud, M; Wang, A; Yang, X; Zhang, X; Feilotter, H E; Tron, V A

    2013-03-07

    In previous studies, we demonstrated that miR-193b expression is reduced in melanoma relative to benign nevi, and also that miR-193b represses cyclin D1 and Mcl-1 expression. We suggested that stathmin 1 (STMN1) might be a target of miR-193b. STMN1 normally regulates microtubule dynamics either by sequestering free tubulin heterodimers or by promoting microtubule catastrophe. Increased expression of STMN1 has been observed in a variety of human malignancies, but its association with melanoma is unknown. We now report that STMN1 is upregulated during the progression of melanoma relative to benign nevi, and that STMN1 is directly regulated by miR-193b. Using an experimental cell culture approach, overexpression of miR-193b using synthetic microRNAs repressed STMN1 expression, whereas inhibition of miR-193b with anti-miR oligos increased STMN1 expression in melanoma cells. The use of a luciferase reporter assay confirmed that miR-193b directly regulates STMN1 by targeting the 3'-untranslated region of STMN1 mRNA. We further demonstrated that STMN1 is overexpressed in malignant melanoma compared with nevi in two independent melanoma cohorts, and that its level is inversely correlated with miR-193b expression. However, STMN1 expression was not significantly associated with patient survival, Breslow depth, mitotic count or patient age. STMN1 knockdown by small-interfering RNA in melanoma cells drastically repressed cell proliferation and migration potential, whereas ectopic expression of STMN1 using lentivirus increased cell proliferation and migration rates. Subsequent gene expression analysis indicated that interconnected cytoskeletal networks are directly affected following STMN1 knockdown. In addition, we identified deregulated genes associated with proliferation and migration, and revealed that p21(Cip1/Waf1) and p27(Kip) could be downstream effectors of STMN1 signaling. Taken together, our study suggests that downregulation of miR-193b may contribute to increased

  17. Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase

    Directory of Open Access Journals (Sweden)

    Suzanne Wolterink-van Loo

    2009-01-01

    Full Text Available Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase (SacKdgA displays optimal activity at 95°C and is studied as a model enzyme for aldol condensation reactions. For application of SacKdgA at lower temperatures, a library of randomly generated mutants was screened for improved synthesis of 2-keto-3-deoxygluconate from pyruvate and glyceraldehyde at the suboptimal temperature of 50 °C. The single mutant SacKdgA-V193A displayed a threefold increase in activity compared with wild type SacKdgA. The increased specific activity at 40–60 °C of this mutant was observed, not only for the condensation of pyruvate with glyceraldehyde, but also for several unnatural acceptor aldehydes. The optimal temperature for activity of SacKdgA-V193A was lower than for the wild type enzyme, but enzymatic stability of the mutant was similar to that of the wild type, indicating that activity and stability were uncoupled. Valine193 has Van der Waals interactions with Lysine153, which covalently binds the substrate during catalysis. The mutation V193A introduced space close to this essential residue, and the increased activity of the mutant presumably resulted from increased flexibility of Lysine153. The increased activity of SacKdgA-V193A with unaffected stability demonstrates the potential for optimizing extremely thermostable aldolases for synthesis reactions at moderate temperatures.

  18. Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase.

    Science.gov (United States)

    Wolterink-van Loo, Suzanne; Siemerink, Marco A J; Perrakis, Georgios; Kaper, Thijs; Kengen, Servé W M; van der Oost, John

    2009-03-02

    Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase (SacKdgA) displays optimal activity at 95 degrees C and is studied as a model enzyme for aldol condensation reactions. For application of SacKdgA at lower temperatures, a library of randomly generated mutants was screened for improved synthesis of 2-keto-3-deoxygluconate from pyruvate and glyceraldehyde at the suboptimal temperature of 50 degrees C. The single mutant SacKdgA-V193A displayed a threefold increase in activity compared with wild type SacKdgA. The increased specific activity at 40-60 degrees C of this mutant was observed, not only for the condensation of pyruvate with glyceraldehyde, but also for several unnatural acceptor aldehydes. The optimal temperature for activity of SacKdgA-V193A was lower than for the wild type enzyme, but enzymatic stability of the mutant was similar to that of the wild type, indicating that activity and stability were uncoupled. Valine193 has Van der Waals interactions with Lysine153, which covalently binds the substrate during catalysis. The mutation V193A introduced space close to this essential residue, and the increased activity of the mutant presumably resulted from increased flexibility of Lysine153. The increased activity of SacKdgA-V193A with unaffected stability demonstrates the potential for optimizing extremely thermostable aldolases for synthesis reactions at moderate temperatures.

  19. Effects of dietary virginiamycin on performance and liver abscess incidence in feedlot cattle.

    Science.gov (United States)

    Rogers, J A; Branine, M E; Miller, C R; Wray, M I; Bartle, S J; Preston, R L; Gill, D R; Pritchard, R H; Stilborn, R P; Bechtol, D T

    1995-01-01

    The effects of dietary virginiamycin level on performance and liver abscesses in feedlot cattle were evaluated in seven dose-response studies. Steers and heifers were fed finishing diets ranging in energy content from 1.34 to 1.51 Mcal of NEg/kg of DM. In all studies, virginiamycin added to the diet improved average daily gain and(or) feed conversion, with no substantial effect on dry matter intake. Pooled analyses of four studies providing virginiamycin at 11.0, 19.3, and 27.6 mg/kg of DM in the complete diet indicated that growth and feed conversion were linearly improved (P virginiamycin at either 19.3 or 27.6 mg/kg. Linear plateau modeling indicated that the effective dose range for virginiamycin in feedlot diets (DM basis) was 19.3 to 27.3 mg/kg for increasing average daily gain, 13.2 to 19.3 mg/kg for improving feed conversion, and 16.5 to 19.3 mg/kg for reducing liver abscess incidence.

  20. X-Ray Crystal Structure and Properties of Phanta, a Weakly Fluorescent Photochromic GFP-Like Protein.

    Directory of Open Access Journals (Sweden)

    Craig Don Paul

    Full Text Available Phanta is a reversibly photoswitching chromoprotein (ΦF, 0.003, useful for pcFRET, that was isolated from a mutagenesis screen of the bright green fluorescent eCGP123 (ΦF, 0.8. We have investigated the contribution of substitutions at positions His193, Thr69 and Gln62, individually and in combination, to the optical properties of Phanta. Single amino acid substitutions at position 193 resulted in proteins with very low ΦF, indicating the importance of this position in controlling the fluorescence efficiency of the variant proteins. The substitution Thr69Val in Phanta was important for supressing the formation of a protonated chromophore species observed in some His193 substituted variants, whereas the substitution Gln62Met did not significantly contribute to the useful optical properties of Phanta. X-ray crystal structures for Phanta (2.3 Å, eCGP123T69V (2.0 Å and eCGP123H193Q (2.2 Å in their non-photoswitched state were determined, revealing the presence of a cis-coplanar chromophore. We conclude that changes in the hydrogen-bonding network supporting the cis-chromophore, and its contacts with the surrounding protein matrix, are responsible for the low fluorescence emission of eCGP123 variants containing a His193 substitution.

  1. X-Ray Crystal Structure and Properties of Phanta, a Weakly Fluorescent Photochromic GFP-Like Protein.

    Science.gov (United States)

    Don Paul, Craig; Traore, Daouda A K; Olsen, Seth; Devenish, Rodney J; Close, Devin W; Bell, Toby D M; Bradbury, Andrew; Wilce, Matthew C J; Prescott, Mark

    2015-01-01

    Phanta is a reversibly photoswitching chromoprotein (ΦF, 0.003), useful for pcFRET, that was isolated from a mutagenesis screen of the bright green fluorescent eCGP123 (ΦF, 0.8). We have investigated the contribution of substitutions at positions His193, Thr69 and Gln62, individually and in combination, to the optical properties of Phanta. Single amino acid substitutions at position 193 resulted in proteins with very low ΦF, indicating the importance of this position in controlling the fluorescence efficiency of the variant proteins. The substitution Thr69Val in Phanta was important for supressing the formation of a protonated chromophore species observed in some His193 substituted variants, whereas the substitution Gln62Met did not significantly contribute to the useful optical properties of Phanta. X-ray crystal structures for Phanta (2.3 Å), eCGP123T69V (2.0 Å) and eCGP123H193Q (2.2 Å) in their non-photoswitched state were determined, revealing the presence of a cis-coplanar chromophore. We conclude that changes in the hydrogen-bonding network supporting the cis-chromophore, and its contacts with the surrounding protein matrix, are responsible for the low fluorescence emission of eCGP123 variants containing a His193 substitution.

  2. New data on cross-sections of deuteron induced nuclear reactions on gold up to 50 MeV and comparison of production routes of medically relevant Au and Hg radioisotopes

    CERN Document Server

    Tárkányi, F; Ditrói, F; Takács, S; Adam-Rebeles, R

    2016-01-01

    Investigations of cross-sections of deuteron induced nuclear reactions on gold were extended up to 50 MeV by using the standard stacked foil irradiation technique and high resolution gamma-ray spectrometry. New cross-sections are reported for the $^{197}$Au(d,xn)$^{197m,197g,195m,195g,193m,193g}$Hg and $^{197}$Au(d,x)$^{198m,198g,196m,196g,195,194}$Au nuclear reactions. The application for production of the medically relevant isotopes $^{198}$Au and $^{195m,195g,197m,197g}$Hg is discussed, including the comparison with other charged particle induced production routes. The possible use of the $^{197}$Au(d,x)$^{197m,197g,195m,193m}$Hg and $^{196m,196g}$Au reactions for monitoring deuteron beam parameters is also investigated.

  3. Solar Wind Associated with Near Equatorial Coronal Hole

    Indian Academy of Sciences (India)

    M. Hegde; K. M. Hiremath; Vijayakumar H. Doddamani; Shashanka R. Gurumath

    2015-09-01

    Present study probes temporal changes in the area and radiative flux of near equatorial coronal hole associated with solar wind parameters such as wind speed, density, magnetic field and temperature. Using high temporal resolution data from SDO/AIA for the two wave-lengths 193 Å and 211 Å, area and radiative flux of coronal holes are extracted and are examined for the association with high speed solar wind parameters. We find a strong association between different parameters of coronal hole and solar wind. For both the wavelength bands, we also compute coronal hole radiative energy near the earth and it is found to be of similar order as that of solar wind energy. However, for the wavelength 193 Å, owing to almost similar magnitudes of energy emitted by coronal hole and energy due to solar wind, it is conjectured that solar wind might have originated around the same height where 193 Å line is formed in the corona.

  4. PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis.

    Science.gov (United States)

    Nielsen, Christian F; Huttner, Diana; Bizard, Anna H; Hirano, Seiki; Li, Tian-Neng; Palmai-Pallag, Timea; Bjerregaard, Victoria A; Liu, Ying; Nigg, Erich A; Wang, Lily Hui-Ching; Hickson, Ian D

    2015-01-01

    PICH is a SNF2 family DNA translocase that binds to ultra-fine DNA bridges (UFBs) in mitosis. Numerous roles for PICH have been proposed from protein depletion experiments, but a consensus has failed to emerge. Here, we report that deletion of PICH in avian cells causes chromosome structural abnormalities, and hypersensitivity to an inhibitor of Topoisomerase II (Topo II), ICRF-193. ICRF-193-treated PICH(-/-) cells undergo sister chromatid non-disjunction in anaphase, and frequently abort cytokinesis. PICH co-localizes with Topo IIα on UFBs and at the ribosomal DNA locus, and the timely resolution of both structures depends on the ATPase activity of PICH. Purified PICH protein strongly stimulates the catalytic activity of Topo II in vitro. Consistent with this, a human PICH(-/-) cell line exhibits chromosome instability and chromosome condensation and decatenation defects similar to those of ICRF-193-treated cells. We propose that PICH and Topo II cooperate to prevent chromosome missegregation events in mitosis.

  5. Dicty_cDB: SLB140 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLB140 (Link to dictyBase) - - - Contig-U16455-1 SLB140Z (Link... to Original site) - - SLB140Z 723 - - - - Show SLB140 Library SL (Link to library) Clone ID SLB140 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLB1-B/SLB140Q.Seq.d/ Representative seq. ID SLB14...0Z (Link to Original site) Representative DNA sequence >SLB140 (SLB140Q) /CSM/SL/SLB1-B/SLB140Q.Seq.d/ XXXXX...3 0.0 SLE193 (SLE193Q) /CSM/SL/SLE1-D/SLE193Q.Seq.d/ 1403 0.0 SLB795 (SLB795Q) /CSM/SL/SLB7-D/SLB795Q.Seq.d/ 1403 0.0 SLB249 (SLB

  6. Dicty_cDB: SLB158 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLB158 (Link to dictyBase) - - - Contig-U16455-1 SLB158Z (Link... to Original site) - - SLB158Z 721 - - - - Show SLB158 Library SL (Link to library) Clone ID SLB158 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLB1-C/SLB158Q.Seq.d/ Representative seq. ID SLB15...8Z (Link to Original site) Representative DNA sequence >SLB158 (SLB158Q) /CSM/SL/SLB1-C/SLB158Q.Seq.d/ XXXXX... SLE193 (SLE193Q) /CSM/SL/SLE1-D/SLE193Q.Seq.d/ 1407 0.0 SLB795 (SLB795Q) /CSM/SL/SLB7-D/SLB795Q.Seq.d/ 1407 0.0 SLB249 (SLB

  7. Screening and Identification of Peptide Interacting with a Single Chain Antibody Against Cell Surface Molecule%用抗细胞表面分子单链抗体筛选和鉴别其相互作用肽

    Institute of Scientific and Technical Information of China (English)

    许静; 李侠; 刘俊霞; 何一心; 韩忠朝; 宋增璇

    2005-01-01

    展示于噬菌体表面的肽库适于用抗体筛选其特异性结合表达肽.scFv-C193是一个抗KG1a细胞表面分子的单链抗体,其抗原仍不清楚,为了筛选并鉴定其识别分子,用scFv-C193筛选了1个展示于T7噬菌体表面的人胎肝cDNA片段库.经4轮生物吸附后分离单个阳性噬斑,并对其表达产物做电泳分析及斑点杂交.结果鉴别出1个scFv-C193结合肽,scFv-C193+克隆噬菌体DNA插入片段的PCR扩增和序列分析结果表明它是1个43bpDNA片段表达产物.BLAST分析EST人类基因数据库,发现它97%相同于CD34+造血干/祖细胞mRNA的1~43bp,提示scFv-C193识别片段存在于人类造血干/祖细胞基因中,单克隆单链抗体scFv-C193可能用于研究这些人类基因的性质.

  8. Generalized Entropies and Legendre Duality

    Science.gov (United States)

    2012-04-22

    Level surfaces of non-degenerate functions in Rn+1, Geometriae Dedicata 50 (1994), 193-204. [3] S.Ivanov: On dual-projectively flat affine... Geometriae Dedicata 56 (1995), 177-184. [8] H.Shima, The geometry of Hessian Structures, World Sci.,(2007). [9] K.Uohashi, A.Ohara and T.Fujii: 1...surfaces of non-degenerate functions in Rn+1, Geometriae Dedicata 50 (1994), 193-204. [3] S. Ivanov, On dual-projectively flat affine connections, J. of

  9. Hi-C Observations of Sunspot Penumbral Bright Dots

    OpenAIRE

    Alpert, Shane E.; Tiwari, Sanjiv K.; Moore, Ronald L.; Winebarger, Amy R.; Savage, Sabrina L.

    2016-01-01

    We report observations of bright dots (BDs) in a sunspot penumbra using High Resolution Coronal Imager (Hi-C) data in 193 \\AA\\ and examine their sizes, lifetimes, speeds, and intensities. The sizes of the BDs are on the order of 1\\arcsec\\ and are therefore hard to identify in the Atmospheric Imaging Assembly (AIA) 193 \\AA\\ images, which have 1.2\\arcsec\\ spatial resolution, but become readily apparent with Hi-C's five times better spatial resolution. We supplement Hi-C data with data from AIA'...

  10. Bright Photoelectron Beams Emitted From Excimer-Laser Illuminated LaB6

    Science.gov (United States)

    Oettinger, Peter E.

    1988-12-01

    Lanthanum hexaboride has traditionally been used as a high-temperature thermionic emitter of electrons. This material, whose work function for a sintered multicrystalline composition is nominally 2.6 eV, appears to be a reasonably good photoemitter when irradiated by UV light. A quantum efficiency of 10-3 was recorded for photoemission at a 193 nm (ArF) incident wavelength. At least 20 A/cm2 were observed at 193 nm, 248 nm (KrF) and 308 (XeC1). Beam brightness appears to be a minimum of 4 x 105 A/cm2-rad2 at 248 nm.

  11. FOOD SAFETY BETWEEN PREVENTION AND MANAGEMENT

    Directory of Open Access Journals (Sweden)

    G. Cagnazzo

    2008-09-01

    Full Text Available Analiysis of key points releted to D.lgs. of November 24th 2007 n. 193 that modify the body of the sistem of control over the Food Safety, abrogating the national regulations regarding the production and marketing of food by animal product; the art. 2, law n. 283 of 1962 and the D. lgs n. 155 of 1977. Analisys of sanctions described on the D. lgs n. 193 of 2007 related to the commission of the illicits in the Pubblic Health and Food Safety sectors.

  12. Drought responses of two bambara groundnut (Vigna subterranea L. Verdc.) landraces collected from a dry and a humid area of Africa

    DEFF Research Database (Denmark)

    Jørgensen, Søren Thorndal; Liu, Fulai; Ouédraogo, M.

    2010-01-01

    Drought adaptation strategies of two bambara groundnut landraces, Uniswa Red and S19-3, collected from contrasting environments in Africa, were compared. Our objectives were to investigate the relative significance of effective stomatal control induced by the abscisic acid (ABA) signalling...... and osmotic adjustment in regulating plant water relations in general for this legume species. The ABA concentration [ABA] in the leaf increased linearly with declining relative leaf water content, and there were significantly higher [ABA] in Uniswa Red compared with S19-3 at the final harvest in the drought...

  13. Immuno-vectorization of radioelements emitters of alpha particles: a new therapy in cancerology; Immunovectorisation de radioelements emetteurs de particules alpha: une nouvelle voie therapeutique en cancerologie

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, M

    2007-05-15

    The radio-immunotherapy is an anti cancerous therapy which consists in vectorising with immuno-specific agents very radio toxic radioelements on tumors or in their environment to destroy them. The first part of this report presents the different characteristics of antibodies as well as their means of production under monoclonal shapes specifically steered against a tumoral antigen of interest. The second part of this report replaces the importance of the immunological vectors in the context of the nuclear medicine. It is notably described that the different methods which allow to radio-label the vector, as well as the different ways of optimization which were envisaged to improve the targeting of radioelements on a tumor. These different developments allow to define the potential place of the alpha radio-immunotherapy in treatments and so re-place the interest of the experimental part. If the radio-immunotherapy, using beta emitters isotopes as the {sup 131}iodine or the{sup 90}yttrium, is today current in anti cancerous therapy, it finds limits because of the disintegration characteristics of the isotopes it uses. Indeed, compared with alpha particles, the beta particles deposit less energy by unit of length in the crossed material.The experimental part of this report aims at studying the feasibility of the coupling between an immunological vector and an alpha emitter isotope.The different tests led on the bismuth 213, the bismuth 212, the lead 212 and the astatine 211 demonstrated that the fixation of these radionuclides was possible. This research theme is strengthened by the construction in Nantes of a cyclotron with high energy ( A.R.R.O.N.A.X.) and the optimization of the obtained promising results should allow a therapeutic use in oncology of the alpha radio-immunotherapy. (N.C.)

  14. Parenting among Low-Income, African American Single Mothers with Preschool-Age Children: Patterns, Predictors, and Developmental Correlates.

    Science.gov (United States)

    McGroder, Sharon M.

    2000-01-01

    Examined dimensions and patterns of parenting among 193 low-income African American single mothers with preschoolers. Identified four parenting patterns (aggravated but nurturant, cognitively stimulating, patient and nurturant, and low nurturance). Found that maternal well-being and sociodemographic characteristics accounted for 93 percent of…

  15. Vibrationally resolved translational energy release spectra from the ultraviolet photodissociation of methyl mercaptan

    Science.gov (United States)

    Segall, J.; Wen, Y.; Singer, R.; Dulligan, M.; Wittig, C.

    1993-11-01

    Product translational energy release spectra resulting from 248 and 193 nm photodissociation of methyl mercaptan are obtained for the hydrogen atom channels (CH3SH+hν→CH3S+H) by using the high-n Rydberg time-of-flight technique. The spectra exhibit vibrational structure that is assigned to a CH3-S stretch progression. At 248 nm, the progression extends only to v=2, while at 193 nm levels up to approximately v=17 are populated. The progression observed at 193 nm is bimodal, with the higher kinetic energy component showing greater spatial anisotropy than the lower energy component, suggesting that two different processes occurring on different time scales are responsible for the two components. The results at 248 nm are consistent with excitation to a repulsive electronic surface. For 193 nm excitation, the high kinetic energy component is consistent with direct photoexcitation to a repulsive surface and/or rapid intramolecular access to a repulsive surface. The lower kinetic energy component presumably derives from the molecule spending more time on an excited surface. A simple model is applied to estimate the extent of C-S bond extension for the various processes.

  16. Vibrationally resolved translational energy release spectra from the ultraviolet photodissociation of methyl mercaptan

    Energy Technology Data Exchange (ETDEWEB)

    Segall, J.; Wen, Y.; Singer, R.; Dulligan, M.; Wittig, C. (Department of Chemistry, University of Southern California, Los Angeles, California 90089 (United States))

    1993-11-01

    Product translational energy release spectra resulting from 248 and 193 nm photodissociation of methyl mercaptan are obtained for the hydrogen atom channels (CH[sub 3]SH+[ital h][nu][r arrow]CH[sub 3]S+H) by using the high-[ital n] Rydberg time-of-flight technique. The spectra exhibit vibrational structure that is assigned to a CH[sub 3]--S stretch progression. At 248 nm, the progression extends only to [ital v]=2, while at 193 nm levels up to approximately [ital v]=17 are populated. The progression observed at 193 nm is bimodal, with the higher kinetic energy component showing greater spatial anisotropy than the lower energy component, suggesting that two different processes occurring on different time scales are responsible for the two components. The results at 248 nm are consistent with excitation to a repulsive electronic surface. For 193 nm excitation, the high kinetic energy component is consistent with direct photoexcitation to a repulsive surface and/or rapid intramolecular access to a repulsive surface. The lower kinetic energy component presumably derives from the molecule spending more time on an excited surface. A simple model is applied to estimate the extent of C--S bond extension for the various processes.

  17. Domain Modeling: NP_001036146.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001036146.1 chr1 The structure of collagen type I. Single type I collagen molecu...le: rigid refinment c1ygvb_ chr1/NP_001036146.1/NP_001036146.1_holo_191-1185.pdb psi-blast 192E,193V,194P,19

  18. Comparison of Reading Performance between Visually Impaired and Normally Sighted Students in Malaysia

    Science.gov (United States)

    Mohammed, Zainora; Omar, Rokiah

    2011-01-01

    The aim of this study is to compare reading performance between visually impaired and normally sighted school children. Participants (n = 299) were divided into three groups: normal vision (NV, n = 193), visually impaired print reader (PR, n = 52), and Braille reader (BR, n = 54). Reading performance was determined by measuring reading rate and…

  19. Hematopoietic stem cell transplantation for infantile osteopetrosis

    NARCIS (Netherlands)

    Orchard, Paul J.; Fasth, Anders L.; Le Rademacher, Jennifer L.; He, Wensheng; Boelens, Jaap Jan; Horwitz, Edwin M.; Al-Seraihy, Amal; Ayas, Mouhab; Bonfim, Carmem M.; Boulad, Farid; Lund, Troy; Buchbinder, David K.; Kapoor, Neena; OBrien, Tracey A.; Perez, Miguel A Diaz; Veys, Paul A.; Eapen, Mary

    2015-01-01

    We report the international experience in outcomes after related and unrelated hematopoietic transplantation for infantile osteopetrosis in 193 patients. Thirty-four percent of transplants used grafts from HLA-matched siblings, 13% from HLA-mismatched relatives, 12% from HLA-matched, and 41% from HL

  20. Content and Timing of Feedback in a Web-based Learning Environment: Effects on Learning as a function of prior knowledge.

    NARCIS (Netherlands)

    Smits, Marieke; Boon, Jo; Sluijsmans, Dominique; Van Gog, Tamara

    2008-01-01

    Smits, M. H. S. B., Boon, J., Sluijsmans, D. M. A., & Van Gog, T. (2008). Content and timing of feedback in a web-based learning environment: Effects on learning as a function of prior knowledge. Interactive Learning Environments, 16, 183-193.

  1. Adverse effects of plant food supplements and botanical preparations

    DEFF Research Database (Denmark)

    Di Lorenzo, Chiara; Ceschi, Alessandro; Kupferschmidt, Hugo

    2015-01-01

    interactions with conventional drugs. Only one case was associated with misidentification. Adverse effects were reported for 39 of the 66 botanical substances searched. Of the total references, 86.6% were associated with 14 plants, including Glycine max/soybean (19.3%), Glycyrrhiza glabra/liquorice (12...

  2. Differentiating Violent and Nonviolent Opiate-Addicted Reformatory Inmates with the MMPI.

    Science.gov (United States)

    Chick, Garry E.; And Others

    1984-01-01

    Discriminated among four groups of male opiate-addicted reformatory inmates (N=193) according to degree of criminal violence using the Minnesota Multiphasic Personality Inventory (MMPI). Results showed that discriminant analysis was moderately successful for classifying Bodily Violent and Nonbodily Violent groups on the basis of their MMPI scores.…

  3. Measuring Adult Literacy Students' Reading Skills Using the Gray Oral Reading Test

    Science.gov (United States)

    Greenberg, Daphne; Pae, Hye Kyeong; Morris, Robin D.; Calhoon, Mary Beth; Nanda, Alice O.

    2009-01-01

    There are not enough reading tests standardized on adults who have very low literacy skills, and therefore tests standardized on children are frequently administered. This study addressed the complexities and problems of using a test normed on children to measure the reading comprehension skills of 193 adults who read at approximately third…

  4. The Influence of Motivation and Adaptation on Students' Subjective Well-Being, Meaning in Life and Academic Performance

    Science.gov (United States)

    Bailey, Thomas Hamilton; Phillips, Lisa J.

    2016-01-01

    High rates of mental illness among students and discontinuation with university studies are regularly reported. The current study sought to explore relationships between motivation, university adaptation and indicators of mental health and well-being and academic performance of 184 first-year university students (73% female, mean age?=?19.3

  5. Changes in Racial Identity among African American College Students Following the Election of Barack Obama

    Science.gov (United States)

    Fuller-Rowell, Thomas E.; Burrow, Anthony L.; Ong, Anthony D.

    2011-01-01

    The current study considered the influence of the 2008 presidential election on the racial identity of African American college students (M[subscript age] = 19.3 years; 26.3% male). The design of the study consisted of 2 components: longitudinal and daily. The longitudinal component assessed 3 dimensions of racial identity (centrality, private…

  6. Group Patient Education: Effectiveness of a Brief Intervention in People with Type 2 Diabetes Mellitus in Primary Health Care in Greece: A Clinically Controlled Trial

    Science.gov (United States)

    Merakou, K.; Knithaki, A.; Karageorgos, G.; Theodoridis, D.; Barbouni, A.

    2015-01-01

    This study aims to assess the impact of a brief patient group education intervention in people with type 2 diabetes mellitus. The sample, 193 people with type 2 diabetes mellitus who were patients at the diabetic clinic of a primary health care setting in Attica, was assigned to two groups, intervention (138 individuals) and control group (55…

  7. Evangelización y sacramentos en la Nueva España (s. XVI) según Jerónimo de Mendieta. Lecciones de ayer para hoy (Reseña)

    OpenAIRE

    Luque-Alcaide, E. (Elisa)

    1994-01-01

    Reseña del libro de Dionisio BOROBIO, Evangelización y sacramentos en la Nueva España (s. XVI) según Jerónimo de Mendieta. Lecciones de ayer para hoy, Servicio de Publicaciones Instituto Teológico Franciscano, Murcia 1992, 193 pp.

  8. 75 FR 5780 - Green Borders Geothermal, LLC, Complainant, v. Terra-Gen Dixie Valley, LLC, Respondent; Notice of...

    Science.gov (United States)

    2010-02-04

    ... System Operator Corp.'s Control Area. \\1\\ Oxbow Power Marketing, Inc., 76 FERC ] 61, 031 (1996) and Oxbow Power Marketing, Inc., 79 FERC ] 61, 193. \\2\\ Promoting Wholesale Competition Through Open Access Non... Policy Study Group, et al. v. FERC, 225 F.3d 667 (D.C. Cir. 2000), cert. granted in part and denied...

  9. 77 FR 65729 - Uranium Enrichment Fuel Cycle Facility Inspection Reports Regarding Louisiana Energy Services LLC...

    Science.gov (United States)

    2012-10-30

    ... COMMISSION Uranium Enrichment Fuel Cycle Facility Inspection Reports Regarding Louisiana Energy Services LLC... inspections of the Louisiana Energy Services (LES), LLC, National Enrichment Facility in Eunice, New Mexico... Title 10 of the Code of Federal Regulations (10 CFR) 70.32 (k) and section 193(c) of the Atomic...

  10. Traumatic Brain Injury in a Military Operational Setting (Le traumatisme cranien dans un cadre militaire operationnel)

    Science.gov (United States)

    2015-01-01

    reproductions of a primary blast, penetrating injuries from fragments, acceleration movements, or combinations of such mechanisms. It is of crucial...pathophysiology. Brain Res Bull . 2011; 85:313-20. [193] Wang, Y., Wei, Y., Oguntayo, S., Wilkins, W., Arun, P. and Valiyaveettil, M., et al. Tightly coupled

  11. The Use of Inhibitors of Mechanosensitive Ion Channels as Local Inhibitors of Peripheral Pain

    Science.gov (United States)

    2013-03-01

    important feature of PIEZO1 that may contribute to the clinical presentation is its ability to pass calcium . The net cation flux through hPIEZO1...Ma JJ, Peng HB (2012) Mechanosensitivity of nicotinic receptors. Pflugers Arch 464(2):193–203. 26. Suchyna TM, et al. (2004) Bilayer-dependent

  12. Dicty_cDB: VSJ669 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available for NADH dehydrogenase 5, partial cds, sample:Mt. Victoria, Chin, Myanmar2,@109. 36 1.2 2 AB059535 |AB05953... dehydrogenase 5, partial cds, sample:Mt. Victoria, Chin, Myanmar1,@93. 36 1.2 2 AB059526 |AB059526.1 Graphi

  13. EST Table: BW999096 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BW999096 SES2266 10/09/28 85 %/193 aa ref|NP_001040402.1| preimplantation protein [...Bombyx mori] gb|ABF51322.1| preimplantation protein [Bombyx mori] 10/08/29 73 %/195 aa FBpp0252287|DwilGK231

  14. AcEST: DK962959 [AcEST

    Lifescience Database Archive (English)

    Full Text Available yl-2'-deoxytaxol N-benzoyltran... 77 1e-13 sp|Q94FT4|SALAT_PAPSO Salutaridinol 7-O-acetyltransferase OS=Pap....LVIVQVTRFTCGGIAVGVTLPHSVCDGRGAAQFVTALAEMARGEVKPSLEPI 193 >sp|Q94FT4|SALAT_PAPSO Salutaridinol 7-O-acetyltran

  15. 75 FR 8431 - Carbon Dioxide Fire Suppression Systems on Commercial Vessels

    Science.gov (United States)

    2010-02-24

    ... Homeland Security Coast Guard 46 Parts 25, 27, 28, et al. Carbon Dioxide Fire Suppression Systems on..., 182, 185, 189, 190, 193, 194, and 196 RIN 1625-AB44 Carbon Dioxide Fire Suppression Systems on... vessels. The amendments would clarify that approved alternatives to carbon dioxide systems may be used...

  16. Communication Technology: Pros and Cons of Constant Connection to Work

    Science.gov (United States)

    Diaz, Ismael; Chiaburu, Dan S.; Zimmerman, Ryan D.; Boswell, Wendy R.

    2012-01-01

    We examined the relationship between employees' attitudes related to communication technology (CT) flexibility, communication technology (CT) use, work-to-life conflict and work satisfaction. Based on data obtained from 193 employees, CT flexibility predicted more CT use. Further, CT use was associated not only with increased work satisfaction,…

  17. EST Table: FS758709 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DICTED: similar to Niemann-Pick Type C-1 CG5722-PA isoform 2 [Apis mellifera] 10/09/08 38 %/193 aa FBpp01472...241956|ref|XP_967619.2| PREDICTED: similar to niemann-pick C1 [Tribolium castaneum] FS758709 fcaL ...

  18. Study of Experimental Aspects of Dynamic Modeling and Control System Analysis of Hovering Fights of Eristalis Hoverflies

    Science.gov (United States)

    2005-11-01

    Matematico e Fisico di Milano, 60:193–203, 1990. [44] J. Milnor. The characteristics of a vector field on the two-sphere. Annals of Mathematics , 58(2):253...257, 1953. [45] J. F. Adams. Vector fields on spheres. Annals of Mathematics , 75(3):603–632, 1962. [46] J. Cantarella, D. DeTurck, and H. Gluck. Vector

  19. 77 FR 62270 - Proposed Revision Treatment of Non-Safety Systems for Passive Advanced Light Water Reactors

    Science.gov (United States)

    2012-10-12

    ... Section 19.3, ``Regulatory Treatment of Non-Safety Systems (RTNSS) for Passive Advanced Light Water...] [FR Doc No: 2012-25110] NUCLEAR REGULATORY COMMISSION [NRC-2012-0237] Proposed Revision Treatment of Non-Safety Systems for Passive Advanced Light Water Reactors AGENCY: Nuclear Regulatory...

  20. 21st Century Conceptions of Musical Ability

    Science.gov (United States)

    Hallam, Susan

    2010-01-01

    This study explored conceptions of musical ability using an inventory derived from previous qualitative research. Participants included 102 musicians, 95 educators, 132 adult amateur musicians, 60 adults who were not actively engaged in making music, 193 children actively engaged in making music in addition to their engagement with the school…

  1. A Study of Outpatient Pharmacy Utilization at Naval Hospital, Camp Lejeune

    Science.gov (United States)

    2002-07-01

    may also be placed on certain drugs based on their potential for abuse or misuse (DoD, 1999). When developing formulary management strategies, it is...FENTANYL 11 $ 2,560.24 BLOOD SUGAR DIAGNOSTIC 28 $ 2,193.86 OXYCODONE HCL/ACETAMINOPHEN 137 $ 2,076.71 METHYLPHENIDATE HCL 31 $ 1,996.63 HYDROCODONE

  2. Diagnóstico ambiental de suelos contaminados por actividades mineras y evaluación de técnicas de estabilización para su recuperación

    OpenAIRE

    Otones Migueláñez, V.

    2014-01-01

    X, 193 páginas. -- Bibliografía: p. 161-180. -- Tesis doctoral. Universidad de Salamanca. Facultad de Ciencias. Departamento de Geología. Instituto de Recursos Naturales y Agrobiología de Salamanca-CSIC. Leída, 31-10-2014

  3. 37 CFR 2.33 - Verified statement.

    Science.gov (United States)

    2010-07-01

    ... behalf of the applicant under § 2.193(e)(1). (b)(1) In an application under section 1(a) of the Act, the... likely, when applied to the goods or services of the other person, to cause confusion or mistake, or to... 44 of the Act, the verified statement must allege: That the applicant has a bona fide intention...

  4. Crisis leadership by mayors: a qualitative content analysis of newspapers and social media on the MH17 disaster.

    NARCIS (Netherlands)

    Jong, W.; Dückers, M.L.A.; Velden, P.G. van der

    2016-01-01

    Malaysia Airlines Flight MH17 crashed in the Ukraine on 17 July 2014 with 193 Dutch passengers on board. The present study assessed which MH17-related activities (or absence of certain activities) of 54 mayors from the Netherlands were mentioned in (social) media and if and how they were evaluated.

  5. Dicty_cDB: Contig-U16424-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 19K01_F.ab1 adult sheep fracture callus 7d ... 40 0.72 3 ( CU654057 ) ovine foetal ovary tissues (Prophase I...sbb001f193d17f0 Sorghum methylation filtered lib... 34 0.70 2 ( DY496661 ) sh2P00

  6. 40 CFR 98.195 - Procedures for estimating missing data.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. For the procedure in § 98.193(b)(2), a complete record of all measured parameters... process data or data used for accounting purposes. (b) For missing values related to the CaO and...

  7. EST Table: CA946075 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available CA946075 KI000114 10/09/28 39 %/193 aa ref|XP_969395.1| PREDICTED: similar to conserved hypothetica...l protein [Tribolium castaneum] gb|EFA00804.1| hypothetical protein TcasGA2_TC003691 [Tribolium ca...: similar to conserved hypothetical protein [Tribolium castaneum] FS915960 L9 ...

  8. Home Literacy Beliefs and Practices among Low-Income Latino Families

    Science.gov (United States)

    Davis, Heather S.; Gonzalez, Jorge E.; Pollard-Durodola, Sharolyn; Saenz, Laura M.; Soares, Denise A.; Resendez, Nora; Zhu, Leina; Hagan-Burke, Shanna

    2016-01-01

    The aim of this study was to explore within-group patterns of variability in the home literacy environments (HLEs) of low-income Latino families using latent profile analysis. Participants were (N = 193) families of Latino preschoolers enrolled in a larger study. In the fall of 2012, mothers filled out a family literacy practices inventory, a…

  9. UNESCO's activities in ethics.

    NARCIS (Netherlands)

    Have, H.A.M.J. ten

    2010-01-01

    UNESCO is an intergovernmental organization with 193 Member States. It is concerned with a broad range of issues regarding education, science and culture. It is the only UN organisation with a mandate in science. Since 1993 it is addressing ethics of science and technology, with special emphasis on

  10. 78 FR 33120 - Final Interim Staff Guidance LR-ISG-2011-04; Updated Aging Management Criteria for Reactor Vessel...

    Science.gov (United States)

    2013-06-03

    ... Evaluation Guidelines (MRP-227-A), dated December 2011 (ADAMS Accession No. ML12017A193 [Transmittal letter from the EPRI-MRP] and ADAMS Accession Nos. ML12017A194, ML12017A196, ML12017A197, ML12017A191... ensure consistency with MRP-227-A and provides a framework to ensure that PWR license renewal...

  11. Anthropometric Survey of US Army Personnel (1988): Correlation Coefficients and Regression Equations. Part 2. Simple and Partial Correlation Tables--Male

    Science.gov (United States)

    1990-05-01

    371’ .355’ .510’ .5"&. .332’ .409’ .319’ We63 .455’ .126w 17 SITCOM *C .291’ .224’ .199’ . 33’ .1%’* .173’ .193’ .1390 .288 .281’ .186’ 1s GITCRUC .3180

  12. Epibiotic community on the acorn barnacle (Balanus amphitrite) from a monsoon-influenced tropical estuary

    Digital Repository Service at National Institute of Oceanography (India)

    Sahoo, G.; Khandeparker, L.

    of Phycology, 23(3), 434-441. Ianora, A., A. Miralto (2010) Toxigenic effects of diatoms on grazers, phytoplankton and other microbes: a review. Ecotoxicology, 19(3), 493-511. Jackson, D., S.P. Leys, V.F. Hinman, R. Woods, M.F. Lavin, B.M. Degnan (2002...

  13. Midway Atoll Site P19 12/5/2002 21-22M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Midway Atoll, site P19 (28.193 N, 177.401 W), between 21 and 22 meters along a permanent transect.

  14. Midway Atoll Site P19 12/5/2002 8-9M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Midway Atoll, site P19 (28.193 N, 177.401 W), between 8 and 9 meters along a permanent transect.

  15. Military Suicide Research Consortium

    Science.gov (United States)

    2013-10-01

    career achievements in research and creative activity. The “References” section contains a listing of the many conference presentations...2003). Problem-solving and cognitive scars in mood and anxiety disorders: The sting of mania . Journal of Social & Clinical Psychology, 22, 193-213

  16. Mustering and evacuation of passengers : scientific basis for design

    NARCIS (Netherlands)

    Boer, L.C.

    1999-01-01

    The capsizing of the HERALD in 1987 (death toll 193) and the ESTONIA in 1994 (death toll 852) have shown that safety can be tenibly insufficient. That is why, since these disasters, moves to improve safety on board ship have gathered momentum. And this had led to the authorities paying special atten

  17. GenousTM endothelial progenitor cell capturing stent vs. the Taxus Liberte stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single-centre, pilot study

    NARCIS (Netherlands)

    M.A.M. Beijk; M. Klomp; N.J.W. Verouden; N. van Geloven; K.T. Koch; J.P.S. Henriques; J. Baan; M.M. Vis; E. Scheunhage; J.J. Piek; J.G.P. Tijssen; R.J. de Winter

    2010-01-01

    Aims The purpose of this study was to evaluate the Genous(TM) endothelial progenitor cell capturing stent vs. the Taxus Liberté paclitaxel-eluting stent in patients with de novo coronary lesions with a high-risk of coronary restenosis. Methods and results We randomly assigned 193 patients with lesio

  18. 19 CFR 10.191 - General.

    Science.gov (United States)

    2010-04-01

    ... directly from a beneficiary country as provided in § 10.193 and which meets the country of origin criteria..., prepared or preserved in any manner, in airtight containers. (iv) Petroleum, or any product derived from petroleum, provided for in headings 2709 and 2710, Harmonized Tariff Schedule of the United States...

  19. Transnational Strategies for the Promotion of Physical Activity and Active Aging: The World Health Organization Model of Consensus Building in International Public Health

    Science.gov (United States)

    Chodzko-Zajko, Wojtek; Schwingel, Andiara

    2009-01-01

    In this paper we focus our attention on an examination of the four-step process adopted by the World Health Organization (WHO) in its systematic campaign to promote physically active lifestyles by older adults across the 193 WHO member states. The four steps adopted by the WHO include (1) Building Consensus Among Professionals; (2) Educating the…

  20. 75 FR 10168 - Information on Foreign Chain of Distribution for Ephedrine, Pseudoephedrine, and Phenylpropanolamine

    Science.gov (United States)

    2010-03-05

    ..., pseudoephedrine, and phenylpropanolamine. In a separate rulemaking, ``Import and Production Quotas for Certain... administer the system of import and production quotas mandated for ephedrine, pseudoephedrine, and... imports of acetone, 110 440 0.5 hour (30 minutes)....... 220 2-butanone, and toluene. Total 193...

  1. Relationship between Professional Values and Critical Thinking Disposition of Science-Technology and Mathematics Teachers

    Science.gov (United States)

    Sahin, Senar Alkin; Tunca, Nihal; Altinkurt, Yahya; Yilmaz, Kürsad

    2016-01-01

    The purpose of this study is to determine the relationship between the professional values and critical thinking disposition of science-technology and mathematics teachers working in middle schools. The survey research method was employed in the study. The sample of the study is comprised of 193 teachers (90 science-technology and 103 mathematics…

  2. Aero-Optics at Shorter Wavelengths.

    Science.gov (United States)

    1980-03-01

    heliostat 1.93 1788 60 coelostat 2.40 2161 60 Changing from a CO2 laser to an iodine laser gives a wavelength ratio of 1/8. Assuming S is fixed, the...thickness and velocity profile. When the wall is concave to the external flow, Gortler vortices may occur. Cooling or heating can alter boundary layer

  3. 2,6-Bis(4-methoxybenzylidenecyclohexanone

    Directory of Open Access Journals (Sweden)

    Deyun Liu

    2009-04-01

    Full Text Available In the title molecule, C22H22O3, the central cyclohexanone ring adopts an envelope conformation. The two outer aromatic rings form a dihedral angle of 19.3 (2°. The crystal packing exhibits weak intermolecular C—H...O hydrogen bonds.

  4. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    DEFF Research Database (Denmark)

    Antoniou, Antonis C; Wang, Xianshu; Fredericksen, Zachary S;

    2010-01-01

    Germline BRCA1 mutations predispose to breast cancer. To identify genetic modifiers of this risk, we performed a genome-wide association study in 1,193 individuals with BRCA1 mutations who were diagnosed with invasive breast cancer under age 40 and 1,190 BRCA1 carriers without breast cancer diagn...

  5. 1-Methyl-3-phenylquinoxalin-2(1H-one

    Directory of Open Access Journals (Sweden)

    Hanane Benzeid

    2009-10-01

    Full Text Available The phenyl substituents in both independent molecules of the title compound, C15H12N2O, are twisted with respect to the quinoxaline system [dihedral angles = 19.3 (1 and 30.4 (1°].

  6. Hollow Promises: The Problem of Culture and the Integration of New Technology into the Navy

    Science.gov (United States)

    2007-11-02

    As a result of this elitism, later American losses were chocked up to poor decisions by commanders, confusion caused by ill-timed or unplanned...Available from http://www.rand.org/publications/IP/IP193/, last accessed 10 March 2004. Gordon, Gilbert. The Rules of the Game : Jutland and British

  7. Verest saab vein : [luuletused] / Mare Osi

    Index Scriptorium Estoniae

    Osi, Mare

    2003-01-01

    Sisu: "Must üü nigu kaaren ..." ; Metamorfoos ; Pettumus ; Skeptiline ; Talisman ; Unetet latsepõli ; Meie kaits ; Sannaõhtu ; "Külmä süä lüüdi lõhki ..." ; "Egäl kevädil ...". Eluloolisi andmeid autori kohta lk. 193

  8. Sex Differences in Arithmetical Performance Scores: Central Tendency and Variability

    Science.gov (United States)

    Martens, R.; Hurks, P. P. M.; Meijs, C.; Wassenberg, R.; Jolles, J.

    2011-01-01

    The present study aimed to analyze sex differences in arithmetical performance in a large-scale sample of 390 children (193 boys) frequenting grades 1-9. Past research in this field has focused primarily on average performance, implicitly assuming homogeneity of variance, for which support is scarce. This article examined sex differences in…

  9. Cohabitation and U.S Adult Mortality: An Examination by Gender and Race

    Science.gov (United States)

    Liu, Hui; Reczek, Corinne

    2012-01-01

    This study is the first to explore the relationship between cohabitation and U.S. adult mortality using a nationally representative sample. Using data from the National Health Interview Survey-Longitudinal Mortality Follow-up files 1997-2004 (N = 193,851), the authors found that divorced, widowed, and never-married White men had higher mortality…

  10. 75 FR 77693 - Noise Exposure Map Notice; Manchester-Boston Regional Airport, Manchester, NH

    Science.gov (United States)

    2010-12-13

    ... Federal Aviation Administration Noise Exposure Map Notice; Manchester-Boston Regional Airport, Manchester... Administration (FAA) announces its determination that the noise exposure maps for Manchester-Boston Regional... Aviation Safety and Noise Abatement Act of 1979 (Pub. L. 96-193) and 14 CFR part 150, are in...

  11. Crisis in the Curriculum? New Counselors' Crisis Preparation, Experiences, and Self-Efficacy

    Science.gov (United States)

    Morris, Carrie A. Wachter; Minton, Casey A. Barrio

    2012-01-01

    Professional counselors are responsible for providing crisis assessment, referral, and intervention (Council for Accreditation of Counseling and Related Educational Programs, 2009); however, little is known about their preparation and experiences in these areas. This study examined new professional counselors' (N= 193) crisis intervention…

  12. Iran: U.S. Concerns and Policy Responses

    Science.gov (United States)

    2010-05-24

    29 Three countries voted no: Malaysia , Cuba, and Venezuela. Six abstained: Afghanistan, Pakistan, Turkey, Brazil, Egypt, and South...S.Res. 193, S.Res. 196, S.Res. 355, and S.Res. 386. Other legislation, such as the “Voice (Victims of Iranian Censorship ) Act” (Subtitle D of the

  13. Dispositional Hope as a Moderator of the Link between Social Comparison with Friends and Eighth-Grade Students' Perceptions of Academic Competence

    Science.gov (United States)

    Bissell-Havran, Joanna M.

    2015-01-01

    We examined the link between social comparison with friends and self-perceptions of academic competence during adolescence and how personality may play a role in this link. Participants were 193 eighth-grade students who attended a rural, mid-Atlantic middle school. We used difference scores to measure the extent to which students' nominated and…

  14. Competency vs. Character? It Must Be Both

    Science.gov (United States)

    2009-12-01

    compass. We must teach moral reasoning, not just ‘core values’ or ‘ethical checklists.’ ”11 Albert Bandura has described the choice to do nothing (or... Albert Bandura , “Moral Disengagement in the Perpetration of Inhumanities,” Personality and Social Psychology Review 3, no. 3, (1999), 193–209; COL(R

  15. Differential Effects of Intelligence, Perceptual Speed and Age on Growth in Attentional Speed and Accuracy

    Science.gov (United States)

    Goldhammer, Frank; Rauch, Wolfgang A.; Schweizer, Karl; Moosbrugger, Helfried

    2010-01-01

    The study investigates the effects of intelligence, perceptual speed and age on intraindividual growth in attentional speed and attentional accuracy over the course of a 6-minute testing session. A sample of 193 subjects completed the Advanced Progressive Matrices and the Vienna Matrices Test representing intelligence, the tests Alertness and…

  16. Aspectos sobre el matrimonio en el Derecho Romano arcaico

    OpenAIRE

    Fern??ndez Baquero, Mar??a-Eva

    2004-01-01

    El libro "El Derecho de Familia: De Roma al Derecho actual" donde se encuentra recogido este cap??tulo "Aspectos sobre el matrimonio en el Derecho Romano arcaico" (p??gs. 193-207) tiene un total de 853 p??ginas.

  17. Influence of Instructor Personality on Student Evaluation of Teaching: A Comparison between English Majors and Non-English Majors

    Science.gov (United States)

    Mori, S.; Tanabe, Y.

    2015-01-01

    160 non-English major students studying at a four-year university and 193 English major students studying at a career college of foreign language in Japan completed a questionnaire regarding instruction and instructor personality. The purpose of the current study was to examine whether the students' instructional and personality ratings predicted…

  18. Employees' Perceptions of Email Communication, Volume and Management Strategies in an Australian University

    Science.gov (United States)

    Pignata, Silvia; Lushington, Kurt; Sloan, Jeremy; Buchanan, Fiona

    2015-01-01

    Despite email playing a central role in university business, little is known about the strategies used by staff to manage email and the factors contributing to email overload. In a mixed method study undertaken in one Australian university comparing academic (n = 193) and professional (n = 278) staff, we found that while email volume was higher in…

  19. A Preliminary Investigation of ADHD Symptoms in Persons with Celiac Disease

    Science.gov (United States)

    Niederhofer, Helmut; Pittschieler, Klaus

    2006-01-01

    Objective: Several studies report a possible association of celiac disease (CD) with psychiatric and psychological disturbances, such as ADHD. Method: The authors assess 132 participants from 3 to 57 years of age (M = 19.3 years) affected by CD for the possibility of an associated ADHD-like symptomatology, using the Conner Scale Hypescheme, a…

  20. COMPORTAMIENTO MECANICO DE LA AORTA ASCENDENTE: CARACTERZACION EXPERIMENTAL Y SIMULACION NUMERICA.

    OpenAIRE

    GARCIA HERRERA, CLAUDIO

    2008-01-01

    En este trabajo se realiza una caracterización experimental y numérica del comportamiento mecánico de la pared de la aorta humana. Se destaca la importancia (le este tema debido al creciente interés cii coiiocer las propiedades y la respuesta mecánica de 193p.

  1. Effects of chronic and periodic exposure to ammonia on growth and blood physiology in juvenile turbot (Scophthalmus maximus)

    NARCIS (Netherlands)

    Foss, A.; Imsland, A.K.; Roth, B.; Schram, E.; Stefansson, S.O.

    2009-01-01

    Juvenile turbot (Scophthalmus maximus) were exposed periodically and chronically to different levels of un-ionised ammonia (UIA-N) and the subsequent effect on growth and food conversion efficiency was studied. Fish with a mean (SD) initial weight 19.3 (3.9) g, were exposed to five treatments consis

  2. Data of evolutionary structure change: 1ALCA-1LMAA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1LMAA 1ALC 1LMA A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...yChain> 1LMA A 1LMA...55 ASP CA 290 1LMA A 1LMA...U CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1LMA... A 1LMAA NRCKGT

  3. Harmony and Disharmony: Exploiting al-Qa’ida’s Organizational Vulnerabilities

    Science.gov (United States)

    2006-02-14

    of suicide missions as a key to gaining popular 37 Newell (1985). 38 Donatella della Porta...Underground,” Terrorism and Political Violence 2 (1990): 193-211. 40 Harmony AFGP-2002-600080. 41 Della Porta (1985), 120, 174. 42 Harmony AFGP-2002

  4. Deterrence of Nuclear Terrorism via Post-Detonation Attribution: Is the United States on Target?

    Science.gov (United States)

    2009-12-01

    analysis of recovered materials. Elemental and isotopic bulk analysis tools include chemical assay, radiochemistry , radioactive counting techniques...disciplines as chemistry, geochemistry, radiochemistry , nuclear physics, radiation physics, and nuclear engineering.193 The current staffing...198 Student enrollment in university graduate radiochemistry programs has dwindled; in fact, less than six doctoral degrees in radiochemistry are

  5. Applicability to Youth Sports of the Leadership Scale for Sports.

    Science.gov (United States)

    Chelladurai, P.; Carron, Albert V.

    1981-01-01

    Item analyses of the responses of 54 high school wrestlers and 193 high school basketball players to the Leadership Scale for Sports support the instrument's applicability in high school sports. The scale taps highly similar response dimensions in varsity and high school athletes. (Author)

  6. NCBI nr-aa BLAST: CBRC-RMAC-02-0030 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-RMAC-02-0030 sp|Q9BDS8|CCR3_MACFA C-C chemokine receptor type 3 (C-C CKR-3) (C...C-CKR-3) (CCR-3) (CCR3) (CKR3) (CD193 antigen) gb|AAK25739.1| chemokine receptor CCR3 [Macaca fascicularis] Q9BDS8 0.0 98% ...

  7. Substance use disorders in forensic psychiatric patients

    NARCIS (Netherlands)

    Kraan, J.; Verkes, R.J.; Goethals, K.; Vissers, A.; Brazil, I.A.; Bulten, B.H.

    2014-01-01

    There is a lack of detailed information on the role of substance use disorders (SUD) as a substantial factor in offences and treatment in forensic psychiatric patients. The aim of this study was to get a better understanding of these specifics. Clinical records of 193 male patients admitted to a Dut

  8. AcEST: BP919323 [AcEST

    Lifescience Database Archive (English)

    Full Text Available apillomavi... 31 5.1 sp|P42854|REG3G_RAT Regenerating islet-derived protein 3 gam...++ P Sbjct: 164 PVYSDPFTLRP--SLPVEGNGRLLTSHPTIAP 193 >sp|P42854|REG3G_RAT Regenerating islet-derived protein

  9. Data of evolutionary structure change: 1ALCA-1VEDA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1VEDA 1ALC 1VED A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...CA 233 THR CA 295 GLU CA 388 TYR CA 428 1VED... A 1VEDA ASP CA 290 1VED A 1VED... CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1VED

  10. Common Aero Vehicle Autonomous Reentry Trajectory Optimization Satisfying Waypoint and No-Fly Zone Constraints

    Science.gov (United States)

    2007-09-01

    Guidance, Control, and Dynamics, 21(2):193–207, March-April 1998. 7. Betts, John T. “A Direct Approach to Solving Optimal Control Problems ,” CSE in...Paul. “Jacobi Pseudospectral Method for Solving Optimal Control Problems ,” Journal of Guidance, Control, and Dynamics, 27(2):293–297, 2004. 117

  11. Foreign Currency Lending in Emerging Europe : Bank Level Evidence

    NARCIS (Netherlands)

    Brown, M.; de Haas, R.

    2010-01-01

    Based on survey data from 193 banks in 20 countries we provide the first bank-level analysis of the determinants of foreign currency (FX) lending in Emerging Europe. We find that FX lending by all banks, regardless of their ownership structure, is strongly determined by the macroeconomic environment

  12. A compact positron annihilation lifetime spectrometer

    Institute of Scientific and Technical Information of China (English)

    李道武; 刘军辉; 章志明; 王宝义; 张天保; 魏龙

    2011-01-01

    Using LYSO scintillator coupled on HAMAMATSU R9800 (a fast photomultiplier) to form the small size γ-ray detectors, a compact lifetime spectrometer has been built for the positron annihilation experiments. The system time resolution FWHM=193 ps and the co

  13. Championing Developing Nations

    Institute of Scientific and Technical Information of China (English)

    Ni Yanshuo

    2011-01-01

    THE United Nations is without doubt the only organization that represents the interests of the entire world and being a member is essential for a country's credibility.That's why when South Sudan became independent recently,the new nation's first move was to join the UN,becoming the 193rd country to attain membership.

  14. Collaboration between the US Forest Service and the USDA Agricultural Research Service on the complementary conservation of crop wild relatives in the United States

    Science.gov (United States)

    Two USDA agencies, the Forest Service (USFS) and the Agricultural Research Service (USDA-ARS) are cooperating on the complementary conservation of crop wild relatives (CWR) native to the United States. The USFS manages 193 million acres of National Forest System lands in 43 states and provides suppo...

  15. Evaluating and Educating - 2000: Is Your Catholic School System Ready? Our Lady of Lourdes Catholic School and Family Partnerships Survey.

    Science.gov (United States)

    Sandoz, Robert J.; Vadenais, Kim Rocha

    Parents attitudes towards traditional Catholic education at Our Lady of Lourdes School (Raleigh, North Carolina) were explored in this study. From 315 surveys sent home to parents, 193 were returned completed. The survey was designed to gather information to improve the partnerships among schools, families, and communities and to prepare Catholic…

  16. Grupo Pensamiento Numérico de la Universidad de Granada. Objetivos e hipótesis de investigación de tesis doctorales hasta el año 1999

    OpenAIRE

    2009-01-01

    Objetivos e hipótesis de tesis doctorales grupo de investigación. didáctica de la matemática. pensamiento numérico Universidad de Granada. Tesis realizadas en el Grupo de Investigación Didáctica de la Matemática. Pensamiento Numérico, FQM-193 del PAIDI (1994- 2009)

  17. Pb isotope evidence for contributions from different Iceland mantle components to Palaeogene East Greenland flood basalts

    DEFF Research Database (Denmark)

    Peate, David; Stecher, Ole

    2003-01-01

    We present new Pb isotope data on 21 samples of break-up-related flood basalts (56–54 Ma) from the Blosseville Kyst region of East Greenland. These samples show a considerable range in isotopic composition (206Pb/204Pb 17.6 to 19.3) that broadly correlates with compositional type. The ‘low-Ti’ type...

  18. Connecting agents and artifacts in CSCL: Towards a rationale of mutual shaping

    NARCIS (Netherlands)

    Overdijk, Maarten; Van Diggelen, Wouter; Kirschner, Paul A.; Baker, Michael

    2012-01-01

    Overdijk, M., Van Diggelen, W., Kirschner, P. A., & Baker, M. (2012). Connecting agents and artifacts in CSCL: Towards a rationale of mutual shaping. International Journal of Computer-Supported Collaborative Learning, 7, 193-210. doi:10.1007/s11412-012-9143-2

  19. EST Table: BP179211 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BP179211 maV32451 10/09/28 100 %/179 aa ref|NP_001136399.1| kynureninase [Bombyx mori] dbj|BAH03383.1| kynur...eninase [Bombyx mori] 10/08/29 n.h 10/08/28 34 %/193 aa C15H9.7#CE06835#WBGene00015802#kynure

  20. Bán, Zsófia and Turai, Hedvig, eds.: "Exposed Memories: Family Pictures in Private and Collective Memory"

    Directory of Open Access Journals (Sweden)

    Katalin Kádár Lynn

    2011-01-01

    Full Text Available Zsófia Bán and Hedvig Turai, eds. Exposed Memories: Family Pictures in Private and Collective Memory. AICA: International Association of Art Critics: Hungarian Section: Distributed by Central European University Press, 2010, 193 pp. Reviewed by Katalin Kádár Lynn, Senior Researcher, ELTE.

  1. State of the Market

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Holiday Week Statistics from the China National Tourism Administration show that during the weeklong National Day holidays, the number of tourists hit 133 million and revenues generated by tourism amounted to 55.9 billion yuan, growing 19.3 percent and 20.7

  2. Can Schools Promote the Health of Children with Asthma?

    Science.gov (United States)

    McWhirter, Jenny; McCann, Donna; Coleman, Helen; Calvert, Marguerite; Warner, John

    2008-01-01

    This report describes the evaluation of a whole-school intervention to improve morbidity and psychosocial well-being in pupils with asthma. In all, 193 children with asthma (7-9 years) from 23 primary/junior schools in the south of England participated. Schools (n = 12) randomly assigned to the intervention group (IV) received a staff asthma…

  3. Improving Nursing Home Care through Training and Job Redesign.

    Science.gov (United States)

    Smyer, Michael; And Others

    1992-01-01

    Short-term longitudinal study assessed single and combined effects of two interventions designed to affect nursing assistants' (n=193) performance by increasing knowledge and motivation. Four sites included skills training only, job redesign only, both interventions, and control. Significant differences were found in knowledge in comparisons…

  4. Bioaccumulation, subcellular distribution and toxicity of sediment-associated copper in the ragworm Nereis diversicolor: The relative importance of aqueous copper, copper oxide nanoparticles and microparticles

    DEFF Research Database (Denmark)

    Thit, Amalie; Banta, Gary Thomas; Selck, Henriette

    2015-01-01

    mean burrowing time increased during exposure to CuAq and CuONP from 0.12 h (controls) to 19.3 and 12.2 h, respectively. All Cu treatments bioaccumulated, especially CuAq (up to 4 times more than the other treatments). Cu was roughly equally distributed among the five subcellular fractions in controls...

  5. "My Baby & Me": Effects of an Early, Comprehensive Parenting Intervention on At-Risk Mothers and Their Children

    Science.gov (United States)

    Guttentag, Cathy L.; Landry, Susan H.; Williams, Jeffrey M.; Baggett, Kathleen M.; Noria, Christine W.; Borkowski, John G.; Swank, Paul R.; Farris, Jaelyn R.; Crawford, April; Lanzi, Robin G.; Carta, Judith J.; Warren, Steven F.; Ramey, Sharon L.

    2014-01-01

    This study examined the efficacy of a multimodule parenting intervention, "My Baby & Me," that began prenatally and continued until children reached 2.5 years of age. The intervention targeted specific parenting skills designed to alter trajectories of maternal and child development. Of 361 high-risk mothers (193 adolescents, 168…

  6. Síndrome de alienación parental en los procesos de divorcio de la pareja /

    OpenAIRE

    Pérez Agüero, María Cristina

    2011-01-01

     tesis que para obtener el grado de Doctor en Psicología, presenta María Cristina Pérez Agüero ; asesor Patricia Andrade Palos. 193 páginas : diagramas. Doctorado en Psicología UNAM, Facultad de Psicología, 2011

  7. TMFunction data: 834 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available N459Q N459 YES Nitrate transport;structural/functional ... High-affinity nitrate tran... Sci U S A. 2004 Dec 14;101(50):17549-54 Nitrate influx assays 0.163±0.026 Km (mM) ... Q8X193_EMENI Helix ... anion transport; membrane protein; nitrate permease; transmembrane domain

  8. Field Medical Surveillance System User’s Manual

    Science.gov (United States)

    2013-01-31

    Paronychia/Infection - Toe 517. Gangrene 518. Necrotizing Fasciitis 519.Impetigo 520.Local Infection/Lesion - Skin 521.Skin Disease - Other 522...190.Nanophyetiasis 165.Marburg virus disease 191. Necrotizing skin/soft tissue infx. 166.Mayaro 192.Neutropenic typhlitis 167.Measles 193.New World

  9. [Mollusks in the Bou Grara Sea (southern, Tunisia): initial biometric data on Cerastoderma glaucum Poirêt, 1789 (Bivalvia, Eulamellibranchia, Cardiae)].

    Science.gov (United States)

    Zaouali, J

    1979-12-01

    The statistical study of Cerastoderma glaucum in the little harbour of Bou Grara points out the presence of 21 ribs on the valves, a mean growth of 19,3 mm for the first year of life and a mean longevity of two years; the formation of rest rings is made at summer period. The dynamical study of the population shows its large homeostasy.

  10. Selected Private Higher Educational Institutions in Metro Manila: A DEA Efficiency Measurement

    Science.gov (United States)

    de Guzman, Maria Corazon Gwendolyn N.; Cabana, Emilyn

    2009-01-01

    This paper measures the technical efficiency of 16 selected colleges and universities in Metro Manila, Philippines, using academic data for the SY 2001-2005. Using the data envelopment analysis (DEA), on average, schools posted 0.807 index score and need additional 19.3% efficiency growth to be efficient. Overall, there are top four efficient…

  11. The Stability of Social Relations among Adolescents with Special Educational Needs (SEN) in Regular Schools in Norway

    Science.gov (United States)

    Frostad, Per; Mjaavatn, Per Egil; Pijl, Sip Jan

    2011-01-01

    The study focuses the stability of friendships of students with special educational needs in regular schools, compared to regular students. The sample consisted of 114 students (M age = 14,4); 22 students (19.3%) were identified by the school as SEN students. The results show that on average, SEN students had fewer stable friendships than their…

  12. The Global Logistics Command: A Strategy to Sustain the Post-War Army

    Science.gov (United States)

    2014-05-22

    sustainment. Because of AMCs innovations during the Vietnam Era, today, AMC supports the Army’s global requirements through forward field...Vehicle (HMMWV), the Personnel Armor System for Ground Troops (PASGT) Kevlar helmet and body armor, the Battle Dress Uniform, the MK19-3 40 mm Grenade

  13. EST Table: FS886342 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available protein [Choristoneura parallela] 10/09/12 40 %/193 aa FBpp0149335|DgriGH15429-PA 10/08/29 n.h 10/09/10 41 %...FS886342 E_FL_ftes_35N22_F_0 10/09/28 58 %/129 aa gb|AAN39695.1| ATP synthase-like

  14. Domain Modeling: NP_683704.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_683704.1 chr1 Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein p2b5lc_ chr1/NP_683704....1/NP_683704.1_holo_16-196.pdb forte 168P,171T,190S,192D,193D,194R _ZN 0 ...

  15. Midway Atoll Site P19 12/5/2002 4-5M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Midway Atoll, site P19 (28.193 N, 177.401 W), between 4 and 5 meters along a permanent transect.

  16. 40 CFR 421.283 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Science.gov (United States)

    2010-07-01

    ....214 Lead 0.098 0.046 Nickel 0.193 0.130 Zinc 0.357 0.147 Tantalum 0.158 (e) Leaching wet air pollution... Tantalum Subcategory § 421.283 Effluent limitations guidelines representing the degree of effluent... application of the best available technology economically achievable: (a) Tantalum alloy leach and rinse....

  17. 76 FR 24465 - Pacific Gas and Electric Company

    Science.gov (United States)

    2011-05-02

    ... Energy Regulatory Commission Pacific Gas and Electric Company Notice of Application Tendered for Filing....: 2310-193. c. Date Filed: April 12, 2011. d. Applicant: Pacific Gas and Electric Company. e. Name of... Contact: Steve Peirano, Relicensing Project Manager, Pacific Gas and Electric Company, P.O. Box...

  18. Unified Methodology for Airport Pavement Analysis and Design. Volume 1. State of the Art

    Science.gov (United States)

    1991-06-01

    pavements with saturated bases and subgrades to well- drained pavements. The damage factors ranged from 10 to 70,000. Cedergren also demonstrated that...34Modulus of Asphalt Mixtures - An Unresolved Dilemma," Transportation Research Board, Research Record 1171, p. 193, Washington, DC 13. Cedergren , H.R

  19. Case Study: South Texas Veterans Health Care System’s Communication Center

    Science.gov (United States)

    2008-07-14

    and the patient-physician relationship. Journal of General Internal Medicine , 14(1), 34-40. Fetter, R. B. & Thompson, J. D. (1966). Patients’ waiting...of appointments kept in an outpatient clinic: a randomized controlled trial. Journal of General Internal Medicine ,\\4(3), 193-196. Johnson, B. J

  20. The Effects of Modern Mathematics Computer Games on Mathematics Achievement and Class Motivation

    Science.gov (United States)

    Kebritchi, Mansureh; Hirumi, Atsusi; Bai, Haiyan

    2010-01-01

    This study examined the effects of a computer game on students' mathematics achievement and motivation, and the role of prior mathematics knowledge, computer skill, and English language skill on their achievement and motivation as they played the game. A total of 193 students and 10 teachers participated in this study. The teachers were randomly…

  1. Construction of Refinery Planned in China's Coastal Area

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ CNOOC plans to build a 12-million-ton-per-year oil refinery in Southeast China's Guangdong Province in the next three years to tap the lucrative oil market in the southern part of the nation. Investment in the project, which was approved by the central government in mid-July, will total at least 16 billion yuan (US$1.93 billion).

  2. Acute Stress Reactions in Couples after a Burn Event to Their Young Child

    NARCIS (Netherlands)

    Bakker, A.; Van Loey, N.E.; Van der Heijden, P.G.M.; Van Son, M.J.M.

    2012-01-01

    Objective This multicenter study examines acute stress reactions in couples following a burn event to their preschool child. Methods Participants were 182 mothers and 154 fathers, including 143 couples, of 193 children (0–4 years) with acute burns. Parents’ self-reported acute stress reactions and e

  3. Comparison of Qinzhou bay wetland landscape information extraction by three methods

    Directory of Open Access Journals (Sweden)

    X. Chang

    2014-04-01

    and OO is 219 km2, 193.70 km2, 217.40 km2 respectively. The result indicates that SC is in the f irst place, followed by OO approach, and the third DT method when used to extract Qingzhou Bay coastal wetland.

  4. RELACIONES Y DISCURSOS ENTRE ATACAMEÑOS, ARQUEOLOGOS Y ESTADO EN ATACAMA (II REGION, NORTE DE CHILE).

    OpenAIRE

    AYALA ROCABADO, RUTH PATRICIA

    2006-01-01

    En esta investigación se aborda el problema de cómo el patrimonio arqueológico y los discursos del pasado forman parte de los movimientos de reivindicación étnica, a la vez que ello contribuye de manera importante a dar forma y sentido al movimiento. Comp 193p.

  5. TABLOG: The Deductive Tableau Programming Language

    Science.gov (United States)

    1988-11-01

    temporal deduction," Logic of Programs Confer- ence, Brooklyn, NY, Lecture Notes in Computer Science 193 (R. Parikh, ed.), Springer- Verlag, June 1985...A. Abadl and Z. Manna, "Modal theorem proving," 8th International Conference on Automated Deduction, Oxford, England, Lecture Notes in Computer Science 230

  6. Domain Modeling: NP_057073.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_057073.3 chr12 HUMAN CYSTEINE SULFINIC ACID DECARBOXYLASE (CSAD) IN COMPLEX WITH... PLP. p2jisb_ chr12/NP_057073.3/NP_057073.3_holo_7-493.pdb blast 93L,151G,152G,153S,154I,156N,190C,193S,244T

  7. Sure How Would the (Imminent) Future Ever Be after Becoming the (Recent) Past? Change in the Irish English "Be after V-ing" Construction.

    Science.gov (United States)

    McCafferty, Kevin

    This paper examines the written use of the "be after V-ing" construction since the reintroduction of English into Ireland. Information comes from publications beginning in 1670, including 193 works by 87 authors providing 1,316 tokens of the construction. Results support Filppula's (1999) view of historical change in the use of this…

  8. The Acquisition of Sight-Singing Skills in Second-Grade General Music: Effects of Using Solfege and of Relating Tonal Patterns to Songs

    Science.gov (United States)

    Reifinger, James L., Jr.

    2012-01-01

    This study was designed to examine two aspects of sight-singing instruction: (1) solfege syllables versus the syllable "loo" for singing patterns and (2) the use of related songs (songs that began with tonal patterns being studied) as compared with unrelated songs. Second-grade students (N = 193) enrolled in general music classes participated in…

  9. Relationship between dioxin and steroid hormones in sera of Vietnamese men

    OpenAIRE

    孫, 献亮

    2015-01-01

    要旨Abstract 以下に掲載:Biomarkers 19(3) pp.236-240 2014. informaheathcare. 共著者:Xian Liang Sun, Teruniko Kido, Rie Okamoto, Ho Dung Manh, Shoko Maruzeni, Muneko Nishijo, Hideaki Nakagawa, Seijiro Honma, Takeshi Nakano, Takumi Takasuga, Dang Duc Nhu, Nguyen Ngoc Hung, and Le Ke Son

  10. History of the Coastal Engineering Research Center 1963-1983, Volume 1

    Science.gov (United States)

    1991-01-01

    Aviv, Israel; and at San Juan. Pue.rto Rico , had demonstrated the tec)mjque. In the United States, offshore breakwaters con- structed in 193lto protect...Research Center pioneered field studies to determine how groins behaved under various Sand Fencing at Padre Island, Texas. 1971 shore conditions

  11. LIPID METABOLISM

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    2004460 Study of plasma acylation-stimulating protein in diabetic and coronary heart disease patients. LU Huiling (卢慧玲), et al. Dept Pediatr, Tongji Hosp, Tongji Med Coll, Huazhong Univ Sci & Technol, Wuhan, 430030. Chin Cir J 2004; 19(3): 187-189.

  12. Bibliography on Aeromedical Research with Abstracts

    Science.gov (United States)

    1959-12-01

    and experimental controls is given. Project 7189 ASTIA No. AD-131058 (12) TN 58-210 September 1958 Biagioni , J. R.; McKelvey, R. K.; Mousted, J. F...D. S. 268, 229 Biagioni , J. R. 12 Clark, W. B. M. 247 Doelling, N. 117 Biesele, R. L., Jr. 286 Clarke, N. P. 160, 166, 176, Dreyer, J. F. 26Z193, 196

  13. 77 FR 27065 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-05-08

    ... average of 14 years earlier than nonsmokers. Moreover, cigarette smoking costs more than $193 billion; $97... Smoking Prevention and Tobacco Control Act (Tobacco Control Act) in 2009, the FDA is legally mandated to... potential adverse consequences of FDA's regulatory actions, as the regulatory framework is being...

  14. Teacher-Student Relationships among Behaviorally At-Risk African American Youth from Low-Income Backgrounds: Student Perceptions, Teacher Perceptions, and Socioemotional Adjustment Correlates

    Science.gov (United States)

    Murray, Christopher; Zvoch, Keith

    2011-01-01

    This investigation examines teacher-student relationships among African American youth from low-income backgrounds (N = 193). Students and their teachers completed measures of teacher-student relationship quality and measures pertaining to emotional, behavioral, and school-related adjustment. Results indicated that African American youth who fell…

  15. Assessment of Junior Doctors' Perceptions of Difficulty of Medical Specialty Training Programs

    Science.gov (United States)

    Rogers, Mary E.; Creed, Peter A.; Searle, Judy

    2012-01-01

    The demands placed on medical trainees by the different specialty training programs are important considerations when choosing a medical specialty. To understand these demands, 193 junior doctors completed a web-based survey, and: (a) ranked medical specialties according to perceived level of training difficulty (incorporating entry difficulty,…

  16. Simulation of High Power Lasers (Preprint)

    Science.gov (United States)

    2010-06-01

    product of laser power. 5. References 1 Wilcox, D. C, Turbulence Modeling for CFD, DCW Industries, Inc. pp. 185-193, July 1998. 2 Menter, F. L...Modeling for CFD, DCW Industries, Inc. pp. 294-296, July 1998. 4 Perram, G. P, .Int. J. Chem. Kinet. 27, 817-28 (1995). 5 Madden, T. J. and Solomon

  17. EST Table: FS760160 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS760160 E_FL_fcaL_13I03_F_0 10/09/28 99 %/193 aa ref|NP_001037584.1| ferritin [Bom...byx mori] gb|ABF51339.1| ferritin isoform 1 [Bombyx mori] gb|ABG76018.1| iron storage protein [Bombyx mori] gb|ABG760

  18. Gclust Server: 193842 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 193842 YelB_CYB_2766 Cluster Sequences - 45 hypothetical protein 1 1.00e-16 0.0 0.0 4.0 0.0 0.0 0.0 Show 193...842 Cluster ID 193842 Sequence ID YelB_CYB_2766 Link to cluster sequences Cluster S

  19. Students’ sense of belonging at school in 41 countries: cross-cultural variability

    NARCIS (Netherlands)

    M.M. Chiu; B.W.Y. Chow; C. McBride; S.T. Mol

    2015-01-01

    This study examined whether students’ sense of belonging at school (SOBAS) differed across attributes of countries, families, schools, teachers, or students. Multilevel analyses of survey and test data from 193,073 15-year-old students in 41 countries yielded four main findings. First, students in m

  20. File list: InP.Liv.50.AllAg.Liver_tumor [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Liv.50.AllAg.Liver_tumor mm9 Input control Liver Liver tumor SRX1008194,SRX1008...193 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Liv.50.AllAg.Liver_tumor.bed ...