WorldWideScience

Sample records for assurance review center

  1. 7 CFR 90.102 - Quality assurance review.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS INTRODUCTION Quality Assurance § 90.102 Quality assurance review. (a) Each laboratory performing tests...

  2. Quality-assurance plan for groundwater activities, U.S. Geological Survey, Washington Water Science Center

    Science.gov (United States)

    Kozar, Mark D.; Kahle, Sue C.

    2013-01-01

    This report documents the standard procedures, policies, and field methods used by the U.S. Geological Survey’s (USGS) Washington Water Science Center staff for activities related to the collection, processing, analysis, storage, and publication of groundwater data. This groundwater quality-assurance plan changes through time to accommodate new methods and requirements developed by the Washington Water Science Center and the USGS Office of Groundwater. The plan is based largely on requirements and guidelines provided by the USGS Office of Groundwater, or the USGS Water Mission Area. Regular updates to this plan represent an integral part of the quality-assurance process. Because numerous policy memoranda have been issued by the Office of Groundwater since the previous groundwater quality assurance plan was written, this report is a substantial revision of the previous report, supplants it, and contains significant additional policies not covered in the previous report. This updated plan includes information related to the organization and responsibilities of USGS Washington Water Science Center staff, training, safety, project proposal development, project review procedures, data collection activities, data processing activities, report review procedures, and archiving of field data and interpretative information pertaining to groundwater flow models, borehole aquifer tests, and aquifer tests. Important updates from the previous groundwater quality assurance plan include: (1) procedures for documenting and archiving of groundwater flow models; (2) revisions to procedures and policies for the creation of sites in the Groundwater Site Inventory database; (3) adoption of new water-level forms to be used within the USGS Washington Water Science Center; (4) procedures for future creation of borehole geophysics, surface geophysics, and aquifer-test archives; and (5) use of the USGS Multi Optional Network Key Entry System software for entry of routine water-level data

  3. Acquisition of certification on quality assurance system ISO9002 in the Tokai Reprocessing Center

    Energy Technology Data Exchange (ETDEWEB)

    Masui, Jinichi; Kobayashi, Kentaro; Iwasaki, Shogo; Fukanoki, Shinji [Japan Nuclear Cycle Development Inst., Tokai Works, Tokai Reprocessing Center, Tokai, Ibaraki (Japan)

    2002-03-01

    On September 6th 2001, Tokai Reprocessing Center obtained Certification under Quality Assurance System ISO9002: 2nd edition 1994 (JIS Z9902: 1998)-Model for quality assurance in production, installation and servicing. In Tokai Reprocessing Plant, quality assurance activities have been undertaken to contribute to the safety and stable operation of the plant based on the JEAG4101 since 1983. Since 1995, the establishment of a quality assurance system based on the ISO9000 series has been underway, and with the fire and explosion incident at the Bituminization Demonstration Facility as a turning point, this activity has been accelerated and certification obtained under ISO9002. These procedures have strengthened quality assurance activities in the plant operation and transparency of the business has been improved for society through an objective evaluation conducted by the International Organization for Standardization. This report describes the details of quality assurance activities until the acquisition of certification and the outline of the established quality assurance system. (author)

  4. Quality assurance of qualitative research: a review of the discourse

    Directory of Open Access Journals (Sweden)

    Reynolds Joanna

    2011-12-01

    Full Text Available Abstract Background Increasing demand for qualitative research within global health has emerged alongside increasing demand for demonstration of quality of research, in line with the evidence-based model of medicine. In quantitative health sciences research, in particular clinical trials, there exist clear and widely-recognised guidelines for conducting quality assurance of research. However, no comparable guidelines exist for qualitative research and although there are long-standing debates on what constitutes 'quality' in qualitative research, the concept of 'quality assurance' has not been explored widely. In acknowledgement of this gap, we sought to review discourses around quality assurance of qualitative research, as a first step towards developing guidance. Methods A range of databases, journals and grey literature sources were searched, and papers were included if they explicitly addressed quality assurance within a qualitative paradigm. A meta-narrative approach was used to review and synthesise the literature. Results Among the 37 papers included in the review, two dominant narratives were interpreted from the literature, reflecting contrasting approaches to quality assurance. The first focuses on demonstrating quality within research outputs; the second focuses on principles for quality practice throughout the research process. The second narrative appears to offer an approach to quality assurance that befits the values of qualitative research, emphasising the need to consider quality throughout the research process. Conclusions The paper identifies the strengths of the approaches represented in each narrative and recommend these are brought together in the development of a flexible framework to help qualitative researchers to define, apply and demonstrate principles of quality in their research.

  5. Surface-water quality-assurance plan for the U.S. Geological Survey Washington Water Science Center

    Science.gov (United States)

    Mastin, Mark C.

    2016-01-01

    This Surface-Water Quality-Assurance Plan documents the standards, policies, and procedures used by the U.S. Geological Survey Washington Water Science Center (WAWSC) for activities related to the collection, processing, storage, analysis, and publication of surface-water data. This plan serves as a guide to all WAWSC personnel involved in surface-water data activities, and changes as the needs and requirements of the WAWSC change. Regular updates to this plan represent an integral part of the quality-assurance process. In the WAWSC, direct oversight and responsibility by the hydrographer(s) assigned to a surface-water station, combined with team approaches in all work efforts, assure high-quality data, analyses, reviews, and reports for cooperating agencies and the public.

  6. Review of SKB's Quality Assurance Programme

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, Tamara D.; Hicks, Timothy W. (Galson Sciences LTD, Oakham, Rutland (United Kingdom))

    2009-06-15

    SKB is preparing a license application for the construction of a final repository for spent nuclear fuel in Sweden. This application will be supported by the safety assessment SR-Site for the post-closure phase. The assessment of long-term safety is based on a broad range of experimental results from laboratory scale, intermediate scale and up to full scale experiments. It is essential that there is a satisfactory level of assurance that experiments have been carried of with sufficient quality, so that results can be considered to be reliable within the context of their use in safety assessment. SSM has initiated a series of reviews of SKB's methods of quality assurance and their implementation. This project includes reviews of the quality assurance (QA) procedures and instructions that have been prepared for the SR-Site assessment as well as reviews of QA implementation at the canister and buffer/backfill laboratories in Oskarshamn, Sweden. The purpose of this project is to assess SKB's quality assurance with the view of providing a good basis for subsequent quality reviews in the context of future licensing. This has been achieved by examination of a number of SKB experiments using a check list, visits to the relevant facilities, and meetings with contractors and a few members of the SKB staff. Overall, the reviewed set of QA documents and instructions do provide reasonably comprehensive coverage of quality-affecting issues relating to the SR-Site safety assessment and, if implemented correctly, will generate confidence in the reliability of the safety assessment results. The results show that the efforts involving quality assurance are increasing within the SKB programme and in general appear to be satisfactory for ongoing experiments and measurements. However, progress in development of the QA documents and instructions has been relatively recent and it may be difficult for these to be fully implemented in the short period remaining before the planned

  7. Computer Center: Software Review.

    Science.gov (United States)

    Duhrkopf, Richard, Ed.; Belshe, John F., Ed.

    1988-01-01

    Reviews a software package, "Mitosis-Meiosis," available for Apple II or IBM computers with colorgraphics capabilities. Describes the documentation, presentation and flexibility of the program. Rates the program based on graphics and usability in a biology classroom. (CW)

  8. Structural Analysis Peer Review for the Static Display of the Orbiter Atlantis at the Kennedy Space Center Visitors Center

    Science.gov (United States)

    Minute, Stephen A.

    2013-01-01

    Mr. Christopher Miller with the Kennedy Space Center (KSC) NASA Safety & Mission Assurance (S&MA) office requested the NASA Engineering and Safety Center's (NESC) technical support on March 15, 2012, to review and make recommendations on the structural analysis being performed for the Orbiter Atlantis static display at the KSC Visitor Center. The principal focus of the assessment was to review the engineering firm's structural analysis for lifting and aligning the orbiter and its static display configuration

  9. Asset Analysis and Operational Concepts for Separation Assurance Flight Testing at Dryden Flight Research Center

    Science.gov (United States)

    Costa, Guillermo J.; Arteaga, Ricardo A.

    2011-01-01

    A preliminary survey of existing separation assurance and collision avoidance advancements, technologies, and efforts has been conducted in order to develop a concept of operations for flight testing autonomous separation assurance at Dryden Flight Research Center. This effort was part of the Unmanned Aerial Systems in the National Airspace System project. The survey focused primarily on separation assurance projects validated through flight testing (including lessons learned), however current forays into the field were also examined. Comparisons between current Dryden flight and range assets were conducted using House of Quality matrices in order to allow project management to make determinations regarding asset utilization for future flight tests. This was conducted in order to establish a body of knowledge of the current collision avoidance landscape, and thus focus Dryden s efforts more effectively towards the providing of assets and test ranges for future flight testing within this research field.

  10. Osseointegration: a review of the fundamentals for assuring cementless skeletal fixation

    Directory of Open Access Journals (Sweden)

    Isaacson BM

    2014-04-01

    Full Text Available Brad M Isaacson,1,2 Sujee Jeyapalina3,4 1Henry M Jackson Foundation for the Advancement of Military Medicine, 2The Center for Rehabilitation Sciences Research, Department of Physical Medicine and Rehabilitation, Uniformed Services University of Health Sciences, Bethesda, MD, USA; 3Department of Orthopedics, 4Orthopedic Research Laboratory, University of Utah, Salt Lake City, UT, USA Abstract: Direct skeletal fixation, termed osseointegration, has expanded in the last century and includes use in total joint replacements, the edentulous mandible and maxilla, and percutaneous osseointegrated prosthetics. Although it is well known that titanium and bone have the ability to form a durable bone–implant interface, new applications have emerged in the field of orthopedics, which requires a more thorough assessment of the literature. This review aims to introduce the basic biological principles for attaining osseointegration and discusses the major factors for assuring successful cementless fixation. Keywords: osseointegration, bone, skeletal attachment, total joint replacements, dental implants, percutaneous

  11. GSFC Safety and Mission Assurance Organization

    Science.gov (United States)

    Kelly, Michael P.

    2010-01-01

    This viewgraph presentation reviews NASA Goddard Space Flight Center's approach to safety and mission assurance. The contents include: 1) NASA GSFC Background; 2) Safety and Mission Assurance Directorate; 3) The Role of SMA-D and the Technical Authority; 4) GSFC Mission assurance Requirements; 5) GSFC Systems Review Office (SRO); 6) GSFC Supply Chain Management Program; and 7) GSFC ISO9001/AS9100 Status Brief.

  12. Quality-assurance and data-management plan for water-quality activities in the Kansas Water Science Center, 2014

    Science.gov (United States)

    Rasmussen, Teresa J.; Bennett, Trudy J.; Foster, Guy M.; Graham, Jennifer L.; Putnam, James E.

    2014-01-01

    As the Nation’s largest water, earth, and biological science and civilian mapping information agency, the U.S. Geological Survey is relied on to collect high-quality data, and produce factual and impartial interpretive reports. This quality-assurance and data-management plan provides guidance for water-quality activities conducted by the Kansas Water Science Center. Policies and procedures are documented for activities related to planning, collecting, storing, documenting, tracking, verifying, approving, archiving, and disseminating water-quality data. The policies and procedures described in this plan complement quality-assurance plans for continuous water-quality monitoring, surface-water, and groundwater activities in Kansas.

  13. 77 FR 23229 - Submission for OMB Review; Assurance of Compliance-Civil Rights Certificate

    Science.gov (United States)

    2012-04-18

    ... Submission for OMB Review; Assurance of Compliance--Civil Rights Certificate SUMMARY: The Office for Civil Rights (OCR) has enforcement responsibilities under several civil rights laws, including Title VI, Title... ``Download Attachments'' to view. Written requests for information should be addressed to U.S. Department...

  14. John F. Kennedy Space Center, Safety, Reliability, Maintainability and Quality Assurance, Survey and Audit Program

    Science.gov (United States)

    1994-01-01

    This document is the product of the KSC Survey and Audit Working Group composed of civil service and contractor Safety, Reliability, and Quality Assurance (SR&QA) personnel. The program described herein provides standardized terminology, uniformity of survey and audit operations, and emphasizes process assessments rather than a program based solely on compliance. The program establishes minimum training requirements, adopts an auditor certification methodology, and includes survey and audit metrics for the audited organizations as well as the auditing organization.

  15. Energy Assurance Technical Training and Awareness Program/Energy Infrastructure Training and Analysis Center

    Energy Technology Data Exchange (ETDEWEB)

    Barbara McCabe

    2005-11-15

    This report covers the work completed during Year One (Year One has a 16 month project period) of a five- year Cooperative Agreement (DE-FC26-03NT41895) between the International Union of Operating Engineers (IUOE) National Hazmat Program (OENHP) and the U. S. Department of Energy (DOE) National Energy Technology Laboratory (NETL). This final technical report is being submitted, as required by the Cooperative Agreement, within 90 (calendar) days after the project period ends (December 31, 2004). The resources allocated to Year One of the Cooperative Agreement were adequate for the completion of the required deliverables. All deliverables have been completed and sent to AAD Document Control as directed in the cooperative agreement. The allocation for Year One required 20-25 trainers to be trained in each of five Train-the-Trainer courses and a total of 6,000 workers trained throughout the country. Through cost savings employed for the scheduling and conduct of Train-the-Trainer, instructor refreshers, and direct training classes, 3171 workers have been trained to date. This total incorporates 159 trainers and members from management, local, county, state and federal organizations identified in the Strategic Plan. The largest percentage of personnel trained is heavy equipment operators, and building engineers, which is the largest targeted population identified under this cooperative agreement. The OENHP, using existing curriculum as appropriate, has modified and developed new training modules that have been used to establish four different levels of training courses. The four courses are: (1) EA 500 Energy Assurance Train-the-Trainer, (2) EA 400 Energy Assurance Instructor Refresher, (3) EA 300 Energy Assurance, and (4) EA 100 Energy Assurance Awareness. Training modules cover topics, such as, but not limited to, facility vulnerability and vulnerability assessment, physical security- heating, ventilation, air conditioning, terrorism awareness, weapons of mass

  16. Colonoscopy Quality Assurance in Ontario: Systematic Review and Clinical Practice Guideline

    Directory of Open Access Journals (Sweden)

    Jill Tinmouth

    2014-01-01

    Full Text Available Colonoscopy is fundamental to the diagnosis and management of digestive diseases and plays a key role in colorectal cancer (CRC screening and diagnosis. Therefore, it is important to ensure that colonoscopy is of high quality. The present guidance document updates the evidence and recommendations in Cancer Care Ontario’s 2007 Colonoscopy Standards, and was conducted under the aegis of the Program in Evidence-Based Care. It is intended to support quality improvement for colonoscopies for all indications, including follow-up to a positive fecal occult blood test, screening for individuals who have a family history of CRC and those at average risk, investigation for symptomatic patients, and surveillance of those with a history of adenomatous polyps or CRC. A systematic review was performed to evaluate the existing evidence concerning the following three key aspects of colonoscopy: physician endoscopist training and maintenance of competency; institutional quality assurance parameters; and colonoscopy quality indicators and auditable outcomes. Where appropriate, indicators were designated quality indicators (where there was sufficient evidence to recommend a specific target and auditable outcomes (insufficient evidence to recommend a specific target, but which should be monitored for quality assurance purposes. The guidance document may be used to support colonoscopy quality assurance programs to improve the quality of colonoscopy regardless of indication. Improvements in colonoscopy quality are anticipated to improve important outcomes in digestive diseases, such as reduction of the incidence of and mortality from CRC.

  17. 34 CFR 366.50 - What assurances shall a center provide and comply with?

    Science.gov (United States)

    2010-07-01

    ... objectives for the center, including overall goals or a mission for the center; (2) A work plan for achieving... Act; (f) The applicant will ensure that the majority of the staff, and individuals in decision-making... management, including making arrangements for an annual independent fiscal audit; (h) The applicant...

  18. FGPA Mission Assurance Center (FMAC) Support Activity at the University of New Mexico

    Science.gov (United States)

    2013-10-31

    two primary tools. The first tool, GNU Radio Companion (GRC), allows the user to drag and drop Digital Signal Processing (DSP) blocks to a workspace...Outputs GRC GNU Radio Companion GSFC NASA Goddard Space Flight Center GUI Graphical User Interface HDL Hardware Descriptive Language HWICAP HardWare...6 4.3 Software Defined Radio (SDR

  19. Toward quality assurance for metaphase FISH: A multi-center experience

    Energy Technology Data Exchange (ETDEWEB)

    Dewald, G. [Mayo Clinic, Rochester, NY (United States); Higgins, R. [Abbott Northwestern Hospital, Minneapolis, MN (United States); Hirsch, B. [Univ. Minnesota Hospitals and Clinics, Minneapolis, MN (United States)] [and others

    1996-09-06

    Although fluorescent in situ hybridization (FISH) is rapidly becoming a part of clinical cytogenetics, no organization sponsors multi-center determinations of the efficacy of probes. We report on 23 laboratories that volunteered to provide slides and to use a probe for SNRPN and a control locus. Experiences with FISH for these laboratories during 1994 ranged from 0 to 645 utilizations (median = 84) involving blood, amniotic fluid and bone marrow. In an initial study of hybridization efficiency, the median percentage of metaphases from normal individuals showing two SNRPN and 2 control signals for slides prepared at each site was 97.0 (range = 74-100); for slides prepared by a central laboratory, it was 97.8 (range = 81.6-100). In a subsequent blind study, each laboratory attempted to score 5 metaphases from each of 23 specimens [8 with del(15)(q11.2{r_arrow}q12) and 15 with normal 15 chromosomes]. Of 529 challenges, the correct SNRPN pattern was found in 5 of 5 metaphases in 457 (86%) and in 4 of 5 in 33 (6%). Ambiguous, incomplete or no results were reported for 32 (6%) challenges. Seven (1%) diagnostic errors were made including 6 false positives and 1 false negative: 1 laboratory made 3 errors, 1 made 2, and 2 made 1 each. Most errors and inconsistencies seemed due to inexperience with FISH. The working time to process and analyze slides singly averaged 49.5 minutes; slides processed in batches of 4 and analyzed singly required 36.9 minutes. We conclude that proficiency testing for FISH using an extensive array of challenges is possible and that multiple centers can collaborate to test probes and to evaluate costs. 10 refs., 1 fig., 4 tabs.

  20. A review of Doppler ultrasound quality assurance protocols and test devices.

    Science.gov (United States)

    Browne, Jacinta E

    2014-11-01

    In this paper, an overview of Doppler ultrasound quality assurance (QA) testing will be presented in three sections. The first section will review the different Doppler ultrasound parameters recommended by professional bodies for use in QA protocols. The second section will include an evaluation and critique of the main test devices used to assess Doppler performance, while the final section of this paper will discuss which of the wide range of test devices have been found to be most suitable for inclusion in Doppler QA programmes. Pulsed Wave Spectral Doppler, Colour Doppler Imaging QA test protocols have been recommended over the years by various professional bodies, including the UK's Institute of Physics and Engineering in Medicine (IPEM), the American Institute for Ultrasound in Medicine (AIUM), and the International Electrotechnical Commission (IEC). However, despite the existence of such recommended test protocols, very few commercial or research test devices exist which can measure the full range of both PW Doppler ultrasound and colour Doppler imaging performance parameters, particularly quality control measurements such as: (i) Doppler sensitivity (ii) colour Doppler spatial resolution (iii) colour Doppler temporal resolution (iv) colour Doppler velocity resolution (v) clutter filter performance and (vi) tissue movement artefact suppression. In this review, the merits of the various commercial and research test devices will be considered and a summary of results obtained from published studies which have made use of some of these Doppler test devices, such as the flow, string, rotating and belt phantom, will be presented.

  1. Emerging technologies and quality assurance in hemostasis: a review of findings from the Royal College of Pathologists of Australasia Quality Assurance Program.

    Science.gov (United States)

    Favaloro, Emmanuel J; Bonar, Roslyn

    2007-04-01

    Regular multilaboratory surveys of laboratories by the Royal College of Pathologists of Australasia Quality Assurance Program (QAP) have been conducted to assess proficiency in tests of hemostasis for the last 40 years. This article focuses primarily on specialized assays of hemostasis, for which surveys have been conducted for some 10 years. For von Willebrand disease (vWD) evaluations, a total of 47 plasma samples have been dispatched to survey participants, including representative samples from normal individuals plus all of the major vWD subtypes (i.e., types 1, 2A, 2B, 2M, 2N, and 3). These surveys have focused partly on the issue of diagnostic interpretive error rates associated with different assays and test panels. In this context, considerable improvement is seen when laboratories incorporate the vWF:collagen-binding assay into the test panel. Thrombophilia-associated tests assessed by the program and discussed in this review include activated protein c resistance, lupus anticoagulant, and deficiencies of protein C, protein S, and antithrombin. Other tests briefly reviewed here include factor assays and inhibitors, D-dimer, and heparin/anti-Xa assays. Anticardiolipin antibody and anti-beta(2)-glycoprotein I antibody (aB(2)GPI) testing, assessed by the Immunology QAP, is also reviewed briefly, as are genetic tests associated with thrombophilic markers such as factor V Leiden and the prothrombin gene.

  2. BYU Food Quality Assurance Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Quality Assurance Lab is located in the Eyring Science Center in the department of Nutrition, Dietetics, and Food Science. The Quality Assurance Lab has about 10...

  3. Quality Assurance Plan for Field Activities at the Natural and Accelerated Bioremediation Research (NABIR) Field Research Center (FRC), Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Brandt, C.C.

    2002-02-28

    The Environmental Sciences Division (ESD) at Oak Ridge National Laboratory (ORNL) has established a Natural and Accelerated Bioremediation Research (NABIR) program Field Research Center (FRC) for the U.S. Department of Energy (DOE) Office of Biological and Environmental Research. The FRC is located in Bear Creek Valley within the Y-12 Plant area of responsibility on DOE's Oak Ridge Reservation in Tennessee. The NABIR program is a long-term effort designed to increase the understanding of fundamental biogeochemical processes that would allow the use of bioremediation approaches for cleaning up DOE's contaminated legacy waste sites. The FRC provides a site for investigators in the NABIR program to conduct research and obtain samples related to in situ bioremediation. The FRC is integrated with existing and future laboratory and field research and provides a means of examining the biogeochemical processes that influence bioremediation under controlled small-scale field conditions. This Quality Assurance Plan (QAP) documents the quality assurance protocols for field and laboratory activities performed by the FRC staff. It supplements the requirements in the ORNL Nuclear Quality Assurance Program and the ESD Quality Assurance Program. The QAP addresses the requirements in Title 10 CFR, Part 830 Subpart A, ''Quality Assurance Requirements'', using a graded approach appropriate for Research and Development projects based on guidance from ''Implementation Guide for Quality Assurance Programs for Basic and Applied Research'' (DOE-ER-STD-6001-92). It also supports the NABIR FRC Management Plan (Watson and Quarles 2000a) which outlines the overall procedures, roles and responsibilities for conducting research at the FRC. The QAP summarizes the organization, work activities, and qualify assurance and quality control protocols that will be used to generate scientifically defensible data at the FRC. The QAP pertains to field

  4. Building High-Performing and Improving Education Systems: Quality Assurance and Accountability. Review

    Science.gov (United States)

    Slater, Liz

    2013-01-01

    Monitoring, evaluation, and quality assurance in their various forms are seen as being one of the foundation stones of high-quality education systems. De Grauwe, writing about "school supervision" in four African countries in 2001, linked the decline in the quality of basic education to the cut in resources for supervision and support.…

  5. 76 FR 5595 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-01

    ... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Immunology. Date: February... Committee: Center for Scientific Review Special Emphasis Panel; Cancer Etiology. Date: February 28, 2011... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  6. 77 FR 57097 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-17

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel; Program Project: Mouse Meiosis... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel; Population Sciences and Epidemiology...

  7. Review: The procurement, storage and quality assurance of frozen blood and tissue biospecimens

    Directory of Open Access Journals (Sweden)

    Manoj S. Charde

    2014-05-01

    Full Text Available The preserved frozen biospecimens are ideal for evaluating the genome, transcriptome, and proteome. Here we present a current overview of experimental data regarding procurement, storage, and quality assurance that can informthe handling of frozen biospecimens. Degradation of frozen biospecimens can be affected by collecting methodology, premortem agonal changes and warm ischemic time during surgery.  Tissue storage at− 80 °C can preserve DNA and protein but RNA show degradation at 5 years, therefore storage at − 150 °C provides significant advantages.  Histologic quality assurance of tissue biospecimens is typically performed at the time of surgery but should also be conducted on the aliquot to be distributed because of tissue heterogeneity.Additional qualityassurance testing should be dictated by the anticipated downstream applications.

  8. 78 FR 55268 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-10

    .... Contact Person: Lee Rosen, Ph.D., Scientific Review Officer, Center for Scientific Review, National...: George M Barnas, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes...

  9. Actions Needed to Ensure Scientific and Technical Information is Adequately Reviewed at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center

    Science.gov (United States)

    2008-01-01

    This audit was initiated in response to a hotline complaint regarding the review, approval, and release of scientific and technical information (STI) at Johnson Space Center. The complainant alleged that Johnson personnel conducting export control reviews of STI were not fully qualified to conduct those reviews and that the reviews often did not occur until after the STI had been publicly released. NASA guidance requires that STI, defined as the results of basic and applied scientific, technical, and related engineering research and development, undergo certain reviews prior to being released outside of NASA or to audiences that include foreign nationals. The process includes technical, national security, export control, copyright, and trade secret (e.g., proprietary data) reviews. The review process was designed to preclude the inappropriate dissemination of sensitive information while ensuring that NASA complies with a requirement of the National Aeronautics and Space Act of 1958 (the Space Act)1 to provide for the widest practicable and appropriate dissemination of information resulting from NASA research activities. We focused our audit on evaluating the STI review process: specifically, determining whether the roles and responsibilities for the review, approval, and release of STI were adequately defined and documented in NASA and Center-level guidance and whether that guidance was effectively implemented at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center. Johnson was included in the review because it was the source of the initial complaint, and Goddard, Langley, and Marshall were included because those Centers consistently produce significant amounts of STI.

  10. Expert panel reviews of research centers: the site visit process.

    Science.gov (United States)

    Lawrenz, Frances; Thao, Mao; Johnson, Kelli

    2012-08-01

    Site visits are used extensively in a variety of settings within the evaluation community. They are especially common in making summative value decisions about the quality and worth of research programs/centers. However, there has been little empirical research and guidance about how to appropriately conduct evaluative site visits of research centers. We review the processes of two site visit examples using an expert panel review: (1) a process to evaluate four university research centers and (2) a process to review a federally sponsored research center. A set of 14 categories describing the expert panel review process was obtained through content analysis and participant observation. Most categories were addressed differently through the two processes highlighting the need for more research about the most effective processes to use within different contexts. Decisions about how to structure site visits appear to depend on the research context, practical considerations, the level at which the review is being conducted and the intended impact of the report. Future research pertaining to the selection of site visitors, the autonomy of the visitors in data collection and report writing, and the amount and type of information provided would be particularly valuable.

  11. 76 FR 74777 - National Marine Protected Areas Center External Review

    Science.gov (United States)

    2011-12-01

    ..., information resources, coordination and policy development. An external review of the MPA Center is needed to... feedback, including public comment on the program's approach to balancing competing priorities. All... of MPAs? Are resources (human and financial) allocated appropriately to effectively address the...

  12. Centers for manufacturing technology: Industrial Advisory Committee Review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    An advisory committee, composed of senior managers form industrial- sector companies and major manufacturing trade associations and representatives from appropriate educational institutions, meets semi-annually to review and advise the Oak Ridge Centers for Manufacturing Technology (ORCMT) on its economic security program. Individual papers have been indexed separately for the database.

  13. 78 FR 30303 - National Contact Center; Submission for OMB Review; National Contact Center Customer Evaluation...

    Science.gov (United States)

    2013-05-22

    ...Under the provisions of the Paperwork Reduction Act, the General Services Administration will be submitting to the Office of Management and Budget (OMB) a request to review and approve an extension of a previously approved information collection requirement regarding the National Contact Center customer evaluation surveys. In this request, the previously approved surveys have been supplemented......

  14. 75 FR 6032 - National Contact Center; Submission for OMB Review; National Contact Center Customer Evaluation...

    Science.gov (United States)

    2010-02-05

    ...Under the provisions of the Paperwork Reduction Act of 1995 (44 U.S.C. Chapter 35), the General Services Administration will be submitting to the Office of Management and Budget (OMB) a request to review and approve a renewal of a previously approved information collection requirement regarding the National Contact Center customer evaluation survey. A request for public comments was published......

  15. Quality Assurance Peer Review Chart Rounds in 2011: A Survey of Academic Institutions in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, Yaacov Richard, E-mail: yaacovla@gmail.com [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Department of Radiation Oncology, Sheba Medical Center, Tel HaShomer (Israel); Sackler School of Medicine, Tel Aviv University (Israel); Whiton, Michal A. [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Department of Radiation Oncology, Skagit Valley Hospital Regional Cancer Care Center, Mt. Vernon, Washington (United States); Symon, Zvi [Department of Radiation Oncology, Sheba Medical Center, Tel HaShomer (Israel); Sackler School of Medicine, Tel Aviv University (Israel); Wuthrick, Evan J. [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Department of Radiation Oncology, Ohio State University, Columbus, Ohio (United States); Doyle, Laura; Harrison, Amy S.; Dicker, Adam P. [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States)

    2012-11-01

    Purpose: In light of concerns regarding the quality of radiation treatment delivery, we surveyed the practice of quality assurance peer review chart rounds at American academic institutions. Methods and Materials: An anonymous web-based survey was sent to the chief resident of each institution across the United States. Results: The response rate was 80% (57/71). The median amount of time spent per patient was 2.7 minutes (range, 0.6-14.4). The mean attendance by senior physicians and residents was 73% and 93%, respectively. A physicist was consistently present at peer review rounds in 66% of departments. There was a close association between attendance by senior physicians and departmental organization: in departments with protected time policies, good attendance was 81% vs. 31% without protected time (p = 0.001), and in departments that documented attendance, attending presence was 69% vs. 29% in departments without documentation (p < 0.05). More than 80% of institutions peer review all external beam therapy courses; however, rates were much lower for other modalities (radiosurgery 58%, brachytherapy 40%-47%). Patient history, chart documentation, and dose prescription were always peer reviewed in >75% of institutions, whereas dosimetric details (beams, wedges), isodose coverage, intensity-modulated radiation therapy constraints, and dose-volume histograms were always peer reviewed in 63%, 59%, 42%, and 50% of cases, respectively. Chart rounds led to both minor (defined as a small multileaf collimator change/repeated port film) and major (change to dose prescription or replan with dosimetry) treatment changes. Whereas at the majority of institutions changes were rare (<10% of cases), 39% and 11% of institutions reported that minor and major changes, respectively, were made to more than 10% of cases. Conclusion: The implementation of peer review chart rounds seems inconsistent across American academic institutions. Brachytherapy and radiosurgical procedures are

  16. 77 FR 30540 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2012-05-23

    ...). Contact Person: Bukhtiar H Shah, DVM, Ph.D., Scientific Review Officer, Center for Scientific Review..., Chicago, IL 60611. Contact Person: Bukhtiar H Shah, Ph.D., DVM, Scientific Review Officer, Center...

  17. 76 FR 52336 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-22

    ... Developmental Neuroscience Integrated Review Group, Neurotransporters, Receptors, and Calcium Signaling Study... HUMAN SERVICES National Institutes of Health Center For Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Epidemiology....

  18. Assurance Cases

    Science.gov (United States)

    2015-01-26

    2015 Carnegie Mellon University Assurance Cases Software Engineering Institute Carnegie Mellon University Pittsburgh, PA 15213 Charles B...1. REPORT DATE 26 JAN 2015 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Assurance Cases 5a. CONTRACT NUMBER 5b. GRANT NUMBER... Assurance Cases Charles B. Weinstock, January 2015 © 2015 Carnegie Mellon University Copyright 2015 Carnegie Mellon University This material is based upon

  19. RAVEN Quality Assurance Activities

    Energy Technology Data Exchange (ETDEWEB)

    Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    This report discusses the quality assurance activities needed to raise the Quality Level of Risk Analysis in a Virtual Environment (RAVEN) from Quality Level 3 to Quality Level 2. This report also describes the general RAVEN quality assurance activities. For improving the quality, reviews of code changes have been instituted, more parts of testing have been automated, and improved packaging has been created. For upgrading the quality level, requirements have been created and the workflow has been improved.

  20. Methods for quality-assurance review of water-quality data in New Jersey

    Science.gov (United States)

    Brown, G. Allan; Pustay, Edward A.; Gibs, Jacob

    2003-01-01

    This report is an instructional and reference manual that describes methods developed and used by the U.S. Geological Survey (USGS), New Jersey District, to assure the accuracy and precision of the results of analyses of surface- and ground-water samples received from analyzing laboratories and, ultimately, to ensure the integrity of water-quality data in USGS databases and published reports. A statistical-analysis computer program, COMP.PPL, is used to determine whether the values reported by the laboratories are internally consistent, whether they are reasonable when compared with values for samples previously collected at the same site, and whether they exceed applicable drinking-water regulations. The program output consists of three files -- QWREVIEW, QWOUTLIERS, and QWCALC. QWREVIEW presents the results of tests of chemical logic and shows values that exceed drinking-water regulations. QWOUTLIERS identifies values that fall outside the historical range of values for the site sampled. QWCALC shows values and calculations used for reference purposes.

  1. Nutrition Program Quality Assurance through a Formalized Process of On-Site Program Review

    Science.gov (United States)

    Paddock, Joan Doyle; Dollahite, Jamie

    2012-01-01

    A protocol for a systematic onsite review of the Expanded Food and Nutrition Education Program and Supplemental Nutrition Assistance Program-Education was developed to support quality programming and ensure compliance with state guidelines and federal regulations. Onsite review of local nutrition program operations is one strategy to meet this…

  2. Enhancing Treatment Outcome of Patients at Risk of Treatment Failure: Meta-Analytic and Mega-Analytic Review of a Psychotherapy Quality Assurance System

    Science.gov (United States)

    Shimokawa, Kenichi; Lambert, Michael J.; Smart, David W.

    2010-01-01

    Objective: Outcome research has documented worsening among a minority of the patient population (5% to 10%). In this study, we conducted a meta-analytic and mega-analytic review of a psychotherapy quality assurance system intended to enhance outcomes in patients at risk of treatment failure. Method: Original data from six major studies conducted…

  3. 77 FR 26771 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-07

    ... for Scientific Review Special Emphasis Panel; PAR 12-053: Advanced Neural Prosthetics R&D. Date: May...: Richard Panniers, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of...). Contact Person: Priscilla B Chen, Ph.D., Scientific Review Officer, Center for Scientific Review,...

  4. 76 FR 24036 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-04-29

    ... Committee: Center for Scientific Review Special Emphasis Panel, Brain Disorders Pathology and Treatment...: Musculoskeletal, Oral and Skin Sciences Integrated Review Group, Musculoskeletal Tissue Engineering Study...

  5. 76 FR 35227 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-16

    ... Scientific Review Special Emphasis Panel; Small Business: Non-HIV Microbial Vaccine Development. Date: July... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Immune Mechanism....

  6. 77 FR 26302 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-03

    ... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Cancer Biology. Date: May....nih.gov . Name of Committee: Immunology Integrated Review Group; Hypersensitivity, Autoimmune,...

  7. 77 FR 5033 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-01

    ... Integrated Review Group; Behavioral Genetics and Epidemiology Study Section. Date: February 22, 2012. Time: 8...: Center for Scientific Review Special Emphasis Panel; Behavioral Genetics and Epidemiology:...

  8. 76 FR 25701 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-05

    ...: Molecular, Cellular and Developmental Neuroscience Integrated Review Group; Synapses, Cytoskeleton and... Committee: Center for Scientific Review Special Emphasis Panel; RFA Panel: Innovations in Molecular...

  9. 77 FR 28886 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-16

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings..., xuguofen@csr.nih.gov . Name of Committee: Molecular, Cellular and Developmental Neuroscience Integrated...: Center for Scientific Review Special Emphasis Panel; Member Conflicts: Renal Physiology...

  10. Review of Quality Assurance in SKB's Repository Research Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Hicks, T.W. [Galson Sciences Ltd, 5 Grosvenor House, Melton Road, Oakham(United Kingdom)

    2007-01-15

    SKB is preparing licence applications for a spent nuclear fuel encapsulation plant and repository which will be supported by the SR-Site safety report. A separate safety report, SR-Can, has been produced by SKB in preparation for the SR-Site report. SKI is in the process of reviewing the SR-Can safety report. In preparation for this review, and with a view to building confidence in SKB's research activities and understanding SKB's handling of data and other information, SKI has examined SKB's application of QA measures in the management and conduct of repository research and development projects that support the SR-Can safety assessment. These preliminary investigations will serve to support the preparation of more detailed quality and technical audits of SKB's repository safety assessment after the submission of a licence application. SKI's approach to this QA review is based on the consideration of quality-affecting aspects of a selection of SKB's research and development activities. As part of this review, SKI identified the need to examine quality-related aspects of some of the many experiments and investigations that form part of SKB's repository research programme. This report presents the findings of such a review, focusing on experiments concerned with the properties and performance of the engineered barrier system. First, in order to establish a broad understanding of QA requirements for repository scientific investigations, QA procedures implemented in the management of research and development activities for the low-level radioactive waste repository near Drigg in the UK and the Waste Isolation Pilot Plant and Yucca Mountain repository projects in the US were studied. The QA procedures for experiments and tests undertaken in these projects were compared with those implemented by SKB. Key findings are: QA programmes have been implemented for each repository development programme in response to regulatory requirements

  11. 78 FR 70313 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-11-25

    ... Committee: Center for Scientific Review Special Emphasis Panel; RFA Panel: Methodologies and Formative Work... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Drive, Bethesda, MD 20892. Contact Person: Jose H Guerrier, Ph.D., Scientific Review Officer, Center...

  12. The peer review system (PRS) for quality assurance and treatment improvement in radiation therapy

    Science.gov (United States)

    Le, Anh H. T.; Kapoor, Rishabh; Palta, Jatinder R.

    2012-02-01

    Peer reviews are needed across all disciplines of medicine to address complex medical challenges in disease care, medical safety, insurance coverage handling, and public safety. Radiation therapy utilizes technologically advanced imaging for treatment planning, often with excellent efficacy. Since planning data requirements are substantial, patients are at risk for repeat diagnostic procedures or suboptimal therapeutic intervention due to a lack of knowledge regarding previous treatments. The Peer Review System (PRS) will make this critical radiation therapy information readily available on demand via Web technology. The PRS system has been developed with current Web technology, .NET framework, and in-house DICOM library. With the advantages of Web server-client architecture, including IIS web server, SOAP Web Services and Silverlight for the client side, the patient data can be visualized through web browser and distributed across multiple locations by the local area network and Internet. This PRS will significantly improve the quality, safety, and accessibility, of treatment plans in cancer therapy. Furthermore, the secure Web-based PRS with DICOM-RT compliance will provide flexible utilities for organization, sorting, and retrieval of imaging studies and treatment plans to optimize the patient treatment and ultimately improve patient safety and treatment quality.

  13. Just in Time Assurance

    Science.gov (United States)

    2010-04-01

    Just in Time Assurance Ji Al F PhD U i it f Id hm ves- oss, , n vers y o a o Director Center for Secure and Dependable Computing W. Mark Vanfleet...COVERED 00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE Just in Time Assurance 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...discusses how practical and affordable recertification can become the norm instead of the rare exception 2 What Does Just in Time Mean? Manufacturing

  14. Optical biosensors for food quality and safety assurance-a review.

    Science.gov (United States)

    Narsaiah, K; Jha, Shyam Narayan; Bhardwaj, Rishi; Sharma, Rajiv; Kumar, Ramesh

    2012-08-01

    Food quality and safety is a scientific discipline describing handling, preparation and storage of food in ways that prevent food borne illness. Food serves as a growth medium for microorganisms that can be pathogenic or cause food spoilage. Therefore, it is imperative to have stringent laws and standards for the preparation, packaging and transportation of food. The conventional methods for detection of food contamination based on culturing, colony counting, chromatography and immunoassay are tedious and time consuming while biosensors have overcome some of these disadvantages. There is growing interest in biosensors due to high specificity, convenience and quick response. Optical biosensors show greater potential for the detection of pathogens, pesticide and drug residues, hygiene monitoring, heavy metals and other toxic substances in the food to check whether it is safe for consumption or not. This review focuses on optical biosensors, the recent developments in the associated instrumentation with emphasis on fiber optic and surface plasmon resonance (SPR) based biosensors for detecting a range of analytes in food samples, the major advantages and challenges associated with optical biosensors. It also briefly covers the different methods employed for the immobilization of bio-molecules used in developing biosensors.

  15. 78 FR 78984 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-12-27

    ... Conference Call). Contact Person: Robert Freund, Ph.D., Scientific Review Officer, Center for Scientific..., Bethesda, MD 20892, (Virtual Meeting). Contact Person: Robert Freund, Ph.D., Scientific Review Officer...). Contact Person: Robert Freund, Ph.D., Scientific Review Officer, Center for Scientific Review,...

  16. 78 FR 21616 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-04-11

    ... Committee: Center for Scientific Review Special Emphasis Panel; Salivary glands, oral microbiology and oral... Call). Contact Person: Priscilla B Chen, Ph.D., Scientific Review Officer, Center for Scientific Review..., MD 20892, (Virtual Meeting). Contact Person: Scott Jakes, Ph.D., Scientific Review Officer,...

  17. 77 FR 55851 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-11

    ...: Jonathan Arias, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of... Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Patricia Greenwel, Ph.D., Scientific Review...

  18. 75 FR 54638 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-08

    ... Drive, Bethesda, MD 20892. (Virtual Meeting.) Contact Person: John Bishop, PhD, Scientific Review...: Michael K. Schmidt, PhD, Scientific Review Officer, Center for Scientific Review, National Institutes...

  19. 77 FR 58144 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-19

    ... Committee: Molecular, Cellular and Developmental Neuroscience Integrated Review Group; Drug Discovery for... Integrated Review Group; Biostatistical Methods and Research Design Study Section. Date: October 19, 2012... Committee: Center for Scientific Review Special Emphasis Panel; PAR11-145: International Research...

  20. 76 FR 51379 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-18

    ..., Nutrition and Reproductive Sciences Integrated Review Group, Integrative Physiology of Obesity and Diabetes... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review Group Biochemistry...

  1. 78 FR 737 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-04

    ... Integrated Review Group; Skeletal Muscle and Exercise Physiology Study Section. Date: February 5-6, 2013... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Integrative, Functional and Cognitive Neuroscience Integrated Review Group; Somatosensory...

  2. 76 FR 1442 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-10

    ... Integrated Review Group; Skeletal Muscle and Exercise Physiology Study Section. Date: February 8-9, 2011... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review Group;...

  3. 77 FR 4049 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-26

    ..., Nutrition and Reproductive Sciences Integrated Review Group, Integrative Physiology of Obesity and Diabetes... Urological Systems Integrated Review Group, Urologic and Genitourinary Physiology and Pathology. Date... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  4. 78 FR 55752 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-11

    ...: Musculoskeletal, Oral and Skin Sciences Integrated Review Group, Skeletal Muscle and Exercise Physiology Study... HUMAN SERVICES National Institutes of Health Center For Scientific Review; Notice of Closed Meetings... Committee: Oncology 2--Translational Clinical Integrated Review Group; Clinical Oncology Study Section....

  5. 75 FR 22819 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-30

    ... Sciences Integrated Review Group; Integrative Physiology of Obesity and Diabetes Study Section. Date: May... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Sciences, Biomedical Imaging and Bioengineering Integrated Review Group; Surgery, Anesthesiology and...

  6. Quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, B.M.; Gleckler, B.P.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the quality assurance and quality control practices of Hanford Site environmental monitoring and surveillance programs. Samples are analyzed according to documented standard analytical procedures. This section discusses specific measures taken to ensure quality in project management, sample collection, and analytical results.

  7. BUILDING "BRIDGES" WITH QUALITY ASSURANCE

    Science.gov (United States)

    The papr describes how, rather than building "bridges" across centuries, quality assurance (QA) personnel have the opportunity to build bridges across technical disciplines, between public and private organizations, and between different QA groups. As reviewers and auditors of a...

  8. 75 FR 32956 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-10

    ... Committee: Center for Scientific Review Special Emphasis Panel, OD-10-005 Director's Opportunity 5 Themes... . Name of Committee: Center for Scientific Review Special Emphasis Panel, Small Business: Cell Biology... and Cartilage Biology. Date: June 30-July 1, 2010. Time: 8:30 a.m. to 5 p.m. Agenda: To review...

  9. 76 FR 11500 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-03-02

    ... Committee: Center for Scientific Review Special Emphasis Panel; Cardiovascular and Autoimmune Disease... Muscle and Exercise Physiology. Date: March 17, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and...: Center for Scientific Review Special Emphasis Panel; Complex Disease Genetics. Date: March 17, 2011....

  10. 78 FR 37837 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-06-24

    ... Committee: Center for Scientific Review Special Emphasis Panel; Program Project: Basic Research on Human Embryonic Stem Cells. Date: July 16-17, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  11. 75 FR 36662 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-28

    ... Committee: Center for Scientific Review Special Emphasis Panel; RFA Panel: Translational Research in Pediatric and Obstetric Pharmacology. Date: July 21, 2010. Time: 11 a.m. to 2:30 p.m. Agenda: To review and... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  12. 76 FR 29770 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-23

    ... for Scientific Review Special Emphasis Panel; PAR10-266: Program Project: NFKB Cell Signal Theory and... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: AIDS/HIV. Date: June...

  13. 76 FR 6805 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-08

    ... Scientific Review Special Emphasis Panel; Small Business: Immunology. Date: March 10-11, 2011. Time: 8:30 a.m... Committee: Center for Scientific Review Special Emphasis Panel; Small Business: Cancer Drug Development and... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  14. 78 FR 12071 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-21

    ... Committee: Center for Scientific Review Special Emphasis Panel; Overflow: Immunology. Date: March 13, 2013... Review Special Emphasis Panel; Small Business: Cancer Drug Development and Therapeutics. Date: March 14... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  15. 76 FR 72208 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2011-11-22

    ... Committee: Center for Scientific Review Special Emphasis Panel; Program Project: Mitosis and Meiosis. Date: December 13-14, 2011. Time: 9 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  16. 77 FR 67015 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-11-08

    ... Committee: Center for Scientific Review Special Emphasis Panel. Program Project: Mitosis and Meiosis. Date: November 27-28, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  17. 77 FR 35417 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-13

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel; Fellowships: Physiology and Pathobiology of... Integrated Review Group; AIDS Molecular and Cellular Biology Study Section. Date: July 9, 2012. Time: 8:00...

  18. 78 FR 9931 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-12

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel; Fellowships: Physiology and Pathobiology of....nih.gov Name of Committee: AIDS and Related Research Integrated Review Group; Behavioral and...

  19. 75 FR 6676 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-10

    ... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Trafficking, Opioid Receptors, Addiction, and Antidepressants. Date: March 3, 2010. Time: 1 p.m. to 3 p.m. Agenda: To review and... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  20. 77 FR 35417 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-13

    ... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Ligand Receptor Interactions of Plasmodium. Date: June 19, 2012. Time: 12:01 a.m. to 11:59 p.m. Agenda: To review and evaluate... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  1. 77 FR 61614 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-10

    ..., (Telephone Conference Call). Contact Person: Patricia Greenwel, Ph.D., Scientific Review Officer, Center for... Emphasis Panel; Member Conflicts: Liver Biology and Pathophysiology. Date: October 31, 2012. Time: 12 p.m... Greenwel, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of...

  2. Ethics review of pediatric multi-center drug trials.

    Science.gov (United States)

    Needham, Allison C; Kapadia, Mufiza Z; Offringa, Martin

    2015-02-01

    The assessment of safety and efficacy of therapeutics for children and adolescents requires the use of multi-centered designs. However, the need to obtain ethical approval from multiple independent research ethics boards (REBs) presents as a challenge to investigators and sponsors who must consider local requirements while ensuring that the protection of human subjects is consistent across sites. In pediatrics, this requirement is complicated by pediatric-specific ethical concerns such as the acquisition of assent and consent and the need for pediatric expertise to assess the scholarly merit of the proposed research. Efforts to tackle these challenges have focused on the process of ethics review, which will improve efficiency. In addition to improving process, we suggest further research to fill gaps in the evidence base for recommendations and decisions made by REBs, specifically their effectiveness to protect human subjects. Evidence gathered will contribute to the successful development, adoption and implementation of harmonized guidance to apply ethics principles in order to protect children through research rather than from research.

  3. 78 FR 16860 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-03-19

    ... Panel; Member Conflict: Endocrinology, Metabolism, Nutrition and Reproductive Sciences. Date: April 9... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Neurodevelopment...

  4. 75 FR 32487 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-08

    ... Committee: Center for Scientific Review Special Emphasis Panel; Fellowship: Neurodevelopment, Synaptic...: Pilot and Feasibility Clinical Studies in Digestive Diseases and Nutrition. Date: June 28-29, 2010....

  5. 77 FR 65698 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2012-10-30

    ... Committee: Center for Scientific Review Special Emphasis Panel, Dating Violence and Marketing. Date... Clary, Program Analyst, Office of Federal Advisory Committee Policy. BILLING CODE 4140-01-P...

  6. 77 FR 58853 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-24

    ... Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: Social Psychology, Family... . (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333,...

  7. 77 FR 1701 - Center For Scientific Review: Notice of Closed Meetings

    Science.gov (United States)

    2012-01-11

    ... applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue Bethesda, MD.... Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street...

  8. 76 FR 27652 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-12

    ... grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue.... Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street,...

  9. 42 CFR 457.495 - State assurance of access to care and procedures to assure quality and appropriateness of care.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false State assurance of access to care and procedures to assure quality and appropriateness of care. 457.495 Section 457.495 Public Health CENTERS FOR MEDICARE... State assurance of access to care and procedures to assure quality and appropriateness of care. A...

  10. Characterization of the peer review network at the Center for Scientific Review, National Institutes of Health.

    Directory of Open Access Journals (Sweden)

    Kevin W Boyack

    Full Text Available The National Institutes of Health (NIH is the largest source of funding for biomedical research in the world. This funding is largely effected through a competitive grants process. Each year the Center for Scientific Review (CSR at NIH manages the evaluation, by peer review, of more than 55,000 grant applications. A relevant management question is how this scientific evaluation system, supported by finite resources, could be continuously evaluated and improved for maximal benefit to the scientific community and the taxpaying public. Towards this purpose, we have created the first system-level description of peer review at CSR by applying text analysis, bibliometric, and graph visualization techniques to administrative records. We identify otherwise latent relationships across scientific clusters, which in turn suggest opportunities for structural reorganization of the system based on expert evaluation. Such studies support the creation of monitoring tools and provide transparency and knowledge to stakeholders.

  11. 75 FR 51081 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-18

    ... Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Pregnancy, Neonatology, and Nutrition. Date: September 7-8, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  12. 78 FR 46593 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2013-08-01

    ... Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: Molecular and Cellular Neurobiology. Date: August 12, 2013. Time: 3:00 p.m. to 6:00 p.m. Agenda: To review and evaluate...

  13. 78 FR 7790 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-04

    ... applications. Place: The Westin St. Francis, 335 Powell Street, San Francisco, CA 94102. Contact Person: Daniel F McDonald, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes...

  14. 77 FR 296 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-04

    ... Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Patricia Greenwel, Ph.D., Scientific Review Officer..., Baltimore, MD 21202. Contact Person: Jonathan Arias, Ph.D., Scientific Review Officer, Center for...

  15. 78 FR 54664 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-05

    ... Bishop, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health... applications. Place: Pier 5 Hotel, 711 Eastern Avenue, Baltimore, MD 21202. Contact Person: Michael...

  16. 75 FR 4090 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-26

    ..., San Diego, CA 92109. Contact Person: George Ann McKie, DVM, PhD., Scientific Review Officer, Center... Drive, San Diego, CA 92109. Contact Person: George Ann McKie, DVM, PhD., Scientific Review...

  17. 77 FR 6809 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-09

    ...: Jacinta Bronte-Tinkew, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes... Post Street, San Francisco, CA 94115. Contact Person: Jacinta Bronte-Tinkew, Ph.D., Scientific...

  18. 78 FR 31951 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-28

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... applications. Place: Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW., Washington, DC 20015... and Epidemiology Integrated Review Group; Infectious Diseases, Reproductive Health, Asthma...

  19. 76 FR 5389 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-31

    ... Immunology. Date: February 24, 2011. Time: 1:30 p.m. to 4:30 p.m. Agenda: To review and evaluate grant...: Center for Scientific Review Special Emphasis Panel Small Business: Cancer Drug Development...

  20. 75 FR 57969 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-23

    ... Committee: Center for Scientific Review Special Emphasis Panel; Small Business: Immunology. Date: October 22... Conflict: Cancer Biomarkers. Date: November 3, 2010. Time: 11 a.m. to 1 p.m. Agenda: To review and...

  1. 76 FR 6803 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-08

    ... p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel & Suites, 2033 M... review and evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center,...

  2. 78 FR 13361 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-27

    ... NW., Washington, DC 20036, Robert Freund, Ph.D., Scientific Review Officer, Center for Scientific... Hotel, 405 Olive Way, Seattle, WA 98101. Contact Person: Robert Freund, Ph.D., Scientific Review...

  3. 77 FR 64118 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-18

    .... Agenda: To review and evaluate grant applications. Place: Doubletree Hotel Bethesda, (Formerly Holiday... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  4. 77 FR 76055 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-12-26

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Emphasis Panel; Member Conflicts: Gastrointestinal Physiology/ Pathophysiology. Date: January 23, 2013... . Name of Committee: Risk, Prevention and Health Behavior Integrated Review Group; Psychosocial Risk...

  5. 75 FR 51277 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-19

    ... Reproductive Sciences Integrated Review Group; Integrative Physiology of Obesity and Diabetes Study Section... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... 20892, 301-443- 8519. Name of Committee: Biological Chemistry and Macromolecular Biophysics...

  6. 77 FR 65569 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-29

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: AIDS and Related Research Integrated Review Group; AIDS Immunology and Pathogenesis Study Section... Special Emphasis Panel; Fellowships: Physiology and Pathobiology of Cardiovascular and Respiratory...

  7. 77 FR 33474 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-06

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings....nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated... Scientific Review Special Emphasis Panel; Muscle Physiology and Musculoskeletal Rehabilitation AREA...

  8. Results of a Quality Assurance Review of External Beam Radiation Therapy in the International Society of Paediatric Oncology (Europe) Neuroblastoma Group's High-risk Neuroblastoma Trial: A SIOPEN Study

    Energy Technology Data Exchange (ETDEWEB)

    Gaze, Mark N., E-mail: mark.gaze@uclh.nhs.uk [Department of Oncology, University College London Hospitals NHS Foundation Trust, London (United Kingdom); Boterberg, Tom [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium); Dieckmann, Karin; Hoermann, Marcus [General Hospital Vienna, Medical University Vienna (Austria); Gains, Jennifer E.; Sullivan, Kevin P. [Department of Oncology, University College London Hospitals NHS Foundation Trust, London (United Kingdom); Ladenstein, Ruth [Children' s Cancer Research Institute, St. Anna Children' s Hospital, Vienna (Austria)

    2013-01-01

    Purpose: Radiation therapy is important for local control in neuroblastoma. This study reviewed the compliance of plans with the radiation therapy guidelines of the International Society of Paediatric Oncology (Europe) Neuroblastoma Group (SIOPEN) High-Risk Trial protocol. Methods and Materials: The SIOPEN trial central electronic database has sections to record diagnostic imaging and radiation therapy planning data. Individual centers may upload data remotely, but not all centers involved in the trial chose to use this system. A quality scoring system was devised based on how well the radiation therapy plan matched the protocol guidelines, to what extent deviations were justified, and whether adverse effects may result. Central review of radiation therapy planning was undertaken retrospectively in 100 patients for whom complete diagnostic and treatment sets were available. Data were reviewed and compared against protocol guidelines by an international team of radiation oncologists and radiologists. For each patient in the sample, the central review team assigned a quality assurance score. Results: It was found that in 48% of patients there was full compliance with protocol requirements. In 29%, there were deviations for justifiable reasons with no likely long-term adverse effects resulting. In 5%, deviations had occurred for justifiable reasons, but that might result in adverse effects. In 1%, there was a deviation with no discernible justification, which would not lead to long-term adverse events. In 17%, unjustified deviations were noted, with a risk of an adverse outcome resulting. Conclusions: Owing to concern over the proportion of patients in whom unjustified deviations were observed, a protocol amendment has been issued. This offers the opportunity for central review of radiation therapy plans before the start of treatment and the treating clinician a chance to modify plans.

  9. 77 FR 54920 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-06

    ... Prosthetics R&D. Date: October 2, 2012. Time: 12 p.m. to 1 p.m. Agenda: To review and evaluate grant..., (Telephone Conference Call). Contact Person: Jane A Doussard-Roosevelt, Ph.D., Scientific Review Officer... Shaw, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of...

  10. Licensing an assured isolation facility for low-level radioactive waste. Volume 2: Recommendations on the content and review of an application

    Energy Technology Data Exchange (ETDEWEB)

    Silverman, D.J.; Bauser, M.A. [Morgan, Lewis and Bockius, Washington, DC (United States); Baird, R.D. [Rogers and Associates Engineering Corp., Salt Lake City, UT (United States)

    1998-07-01

    This report provides a detailed set of proposed criteria and guidance for the preparation of a license application for an assured isolation facility (AIF). The report is intended to provide a detailed planning basis upon which a prospective applicant may begin pre-licensing discussions with the Nuclear Regulatory Commission and initiate development of a license application. The report may also be useful to the NRC or to state regulatory agencies that may be asked to review such an application. Volume 1 of this report provides background information, and describes the licensing approach and methodology. Volume 2 identifies specific information that is recommended for inclusion in a license application.

  11. 78 FR 23276 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-04-18

    ..., pughjohn@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel RFA RM12-015...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; PAR-11-246: Translational Research in Pediatric and Obstetric Pharmacology. Date: May 14, 2013. Time: 12:00 p.m. to 3:00...

  12. 78 FR 11896 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-20

    ... Committee: Center for Scientific Review Special Emphasis Panel; Translational Research in Diabetes, Obesity..., 301-408- 9901, sheardn@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis..., Room 6158, MSC 7892, Bethesda, MD 20892, 301-435-1355, debernardima@csr.nih.gov . Name of...

  13. 75 FR 17416 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-06

    ...-408- 9129, lewisdeb@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Cancer Research. Date: April 21, 2010. Time: 3 p.m. to 5 p.m. Agenda: To review..., Bethesda, MD 20892, (301) 451- 4467, choe@csr.nih.gov . Name of Committee: Center for Scientific...

  14. 76 FR 10910 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-28

    ..., Room 4040A, MSC 7806, Bethesda, MD 20892. (301) 594-1245. ivinsj@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; RFA-HD-11-101: Sleep and Social Environment: Basic...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel;...

  15. 77 FR 50139 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-08-20

    ... Committee: Center for Scientific Review Special Emphasis Panel; Skeletal Integrity and Environment. Date... Health, 6701 Rockledge Drive, Room 5217B, MSC 7846, Bethesda, MD 20892, 301-435- 1259, nadis@csr.nih.gov..., xuguofen@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel;...

  16. 78 FR 24428 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-04-25

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: Cancer Biology and Genetics... Conflict: Neural Engineering and Neurogenetics. Date: May 22, 2013. Time: 2:00 p.m. to 5:00 p.m. Agenda:...

  17. 77 FR 18268 - Proposal Review Panel for Engineering Education and Centers; Notice of Meeting

    Science.gov (United States)

    2012-03-27

    ... Proposal Review Panel for Engineering Education and Centers; Notice of Meeting In accordance with the... the following meeting: Name: Proposal Review Panel for Engineering Education and Centers ( 173). Date... 3:30 p.m.--7:30 p.m. Closed--ERC Education Program Thursday, March 29, 2012 8 a.m.-9 a.m....

  18. 75 FR 67751 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2010-11-03

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Center for Scientific Review Special Emphasis... Obstetric Pharmacology''. The meeting is closed to the public. ] Dated: October 28, 2010. Jennifer S....

  19. 75 FR 60465 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-30

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflicts: Asthma... Chevy Chase Pavilion, 4300 Military Road, NW., Washington, DC 20015. Contact Person: Alexander D...

  20. 75 FR 1399 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-11

    ... Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Cheryl M. Corsaro, PhD... review and evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400... review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street, NW., Washington,...

  1. 78 FR 65345 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Center for Scientific Review Special Emphasis Panel, Molecular Neuroscience of Channels and Receptors, October 18, 2013, 1:00 p.m. to October 18,...

  2. A Client-Centered Review of Rogers with Gloria

    Science.gov (United States)

    Moon, Kathryn A.

    2007-01-01

    Carl Rogers's nondirective theory and his response style with Gloria (E. L. Shostrom, 1965) are discussed in reply to S. A. Wickman and C. Campbell's (2003) "An Analysis of How Carl Rogers Enacted Client-Centered Conversation With Gloria." Client-centered studies of C. Rogers's transcripts give context for reformulating S. A. Wickman and C.…

  3. NASA's Approach to Software Assurance

    Science.gov (United States)

    Wetherholt, Martha

    2015-01-01

    NASA defines software assurance as: the planned and systematic set of activities that ensure conformance of software life cycle processes and products to requirements, standards, and procedures via quality, safety, reliability, and independent verification and validation. NASA's implementation of this approach to the quality, safety, reliability, security and verification and validation of software is brought together in one discipline, software assurance. Organizationally, NASA has software assurance at each NASA center, a Software Assurance Manager at NASA Headquarters, a Software Assurance Technical Fellow (currently the same person as the SA Manager), and an Independent Verification and Validation Organization with its own facility. An umbrella risk mitigation strategy for safety and mission success assurance of NASA's software, software assurance covers a wide area and is better structured to address the dynamic changes in how software is developed, used, and managed, as well as it's increasingly complex functionality. Being flexible, risk based, and prepared for challenges in software at NASA is essential, especially as much of our software is unique for each mission.

  4. Preventive design review as quality assurance and further task at Kawasaki Heavy Industries, Ltd.; Kawasaki Juko ni okeru jizen kensho no torikumi to kongo no tenkai

    Energy Technology Data Exchange (ETDEWEB)

    Minakata, S.; Okazaki, S.; Nishimoto, T.; Saeki, H.; Niguma, Y. [Kawasaki Heavy Industries, Ltd., Kobe (Japan)

    1999-12-01

    At Kawasaki Heavy Industries, Ltd. (KHI), to reduce the risk in manufacturing and contribute to our company management, the most useful method of our Quality Assurance (QA) activities is preventive verification by design reviews (DR). During a design review, we effectively use the abundant experience of our company in the technologies of design, manufacturing and management to prevent failures resulting from the upper processes, such as design. As a direct result of this activity (GRP-50 and 75), failure costs have been greatly reduced. In the future we will continue to evolve our QA activities backed by preventive verification, aiming at linking Total Quality Management (TQM) to management in order to progress our company management and business process. (author)

  5. 75 FR 59728 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-28

    ...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Stem Cells in... Development and Mineralization. Date: November 3, 2010. Time: 3 p.m. to 5:30 p.m. Agenda: To review and... Scientific Review Special Emphasis Panel; Fellowship: Technology Development. Date: November 17-18,...

  6. 78 FR 30319 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-22

    ... Committee: Center for Scientific Review Special Emphasis Panel; Hypersensitivity, Autoimmune, and Immune-mediated Disease Overflow. Date: June 7, 2013. Time: 11:00 a.m. to 2:00 p.m. Agenda: To review and evaluate... Integrated Review Group; Gene and Drug Delivery Systems Study Section. Date: June 13-14, 2013. Time: 8:00...

  7. 77 FR 30021 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2012-05-21

    ... Molecular Biology of Glia Study Section. Date: June 14, 2012. Time: 8:00 a.m. to 7:00 p.m. Agenda: To review...: Center for Scientific Review Special Emphasis Panel; Member Conflict: Skeletal Biology and Biomaterials.... Agenda: To review and evaluate grant applications. Place: Marina del Rey Hotel, 13534 Bali Way,...

  8. 76 FR 5182 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-28

    ... . Name of Committee: Center for Scientific Review Special Emphasis Panel, Small Business: Molecular, Cellular, and Developmental Neurobiology. Date: March 4, 2011. Time: 10 a.m. to 5 p.m. Agenda: To review... Molecular Screening (R21). Date: March 2-3, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and...

  9. 78 FR 738 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-04

    ... Committee: Center for Scientific Review Special Emphasis Panel Member Conflict: Cancer Therapeutics. Date....nih.gov . Name of Committee: Oncology 1-Basic Translational Integrated Review Group; Cancer Genetics...: Immunology Integrated Review Group; Cellular and Molecular Immunology--B Study Section. Date: February...

  10. 78 FR 32260 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-29

    ... Committee: Center for Scientific Review Special Emphasis Panel Cancer Therapeutics. Date: June 24, 2013... Integrated Review Group Cancer Genetics Study Section. Date: June 27-28, 2013. Time: 8:00 a.m. to 5:00 p.m...@csr.nih.gov . Name of Committee: Immunology Integrated Review Group Immunity and Host Defense...

  11. 75 FR 54896 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-09

    ..., 2010. Time: 8:30 a.m. to 7 p.m. Agenda: To review and evaluate grant applications. Place: George... Review Special Emphasis Panel; Small Business: Healthcare Delivery and Methodologies. Date: October 14-15...: Center for Scientific Review Special Emphasis Panel; PAR-10-174: International Research Ethics...

  12. 77 FR 12319 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-29

    ... Review Special Emphasis Panel; RFA-HD-12-204: Sleep and Social Environment: Basic Biopsychosocial... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Behavior. Date: March 12, 2012. Time: 2 p.m. to 3:30 p.m. Agenda: To review and evaluate grant...

  13. 75 FR 33626 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-14

    ... Committee: Center for Scientific Review Special Emphasis Panel; Small Business: Rehabilitation Sciences... Panel; Small Business: Digestive Sciences. Date: July 14, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review... Review Special Emphasis Panel; PAR-TW-10-008: Medical Education Partnership Initiative (MEPI)...

  14. 75 FR 6044 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-05

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings.... micklinm@csr.nih.gov . Name of Committee: AIDS and Related Research Integrated Review Group, AIDS Molecular... Physiology. Date: March 9-10, 2010. Time: 9 a.m. to 6 p.m. Agenda: To review and evaluate grant...

  15. 77 FR 32652 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-01

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings...: Genes, Genomes, and Genetics Integrated Review Group Molecular Genetics A Study Section. Date: June 25... for Scientific Review Special Emphasis Panel Skeletal Muscle Biology, Physiology and Disease....

  16. 76 FR 57063 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-15

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Musculoskeletal, Oral And Skin Sciences Integrated Review Group; Skeletal Muscle and Exercise Physiology Study Section Date: October 3-4, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  17. 78 FR 54259 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-03

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... and Training Neurosciences Integrated Review Group; Molecular Neurogenetics Study Section. Date... Physiology and Pathophysiology. Date: September 26, 2013. Time: 1:00 p.m. to 4:30 p.m. Agenda: To review...

  18. 78 FR 5190 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-24

    ..., Nutrition and Reproductive Sciences Integrated Review Group; Integrative Physiology of Obesity and Diabetes... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings..., greenbergwa@csr.nih.gov . Name of Committee: Musculoskeletal, Oral and Skin Sciences Integrated Review...

  19. 75 FR 26970 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-13

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Musculoskeletal, Oral and Skin Sciences Integrated Review Group, Skeletal Muscle and Exercise Physiology Study Section. Date: June 3-4, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  20. 75 FR 57042 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-17

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Musculoskeletal, Oral and Skin Sciences Integrated Review Group; Skeletal Muscle and Exercise Physiology Study Section. Date: October 12-13, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and...

  1. 78 FR 60297 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-10-01

    ...: Endocrinology, Metabolism, Nutrition and Reproductive ] Sciences Integrated Review Group; Integrative Physiology... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Integrated Review Group; Neural Oxidative Metabolism and Death Study Section. Date: October 24-25, 2013....

  2. 77 FR 9672 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-17

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings....nih.gov . Name of Committee: AIDS and Related Research Integrated Review Group; Behavioral and Social... Scientific Review Special Emphasis Panel; Fellowships: Physiology and Pathobiology of Cardiovascular...

  3. 77 FR 511 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-05

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Neurosciences Integrated Review Group, Bioengineering of Neuroscience, Vision and Low Vision Technologies Study..., Physiology and Robotics. Date: February 1, 2012. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate...

  4. User-centered design to develop clinical applications. Literature review.

    Science.gov (United States)

    Luna, Daniel; Quispe, María; Gonzalez, Zulma; Alemrares, Alfredo; Risk, Marcelo; Garcia Aurelio, Mauro; Otero, Carlos

    2015-01-01

    User-centered design is mentioned by Norman as "the need for a design that uses the natural properties of the individuals, exploiting the relationships and constraints and focusing on the needs and interests of the user, in order to make the final products usable and understandable". This is also important in health developments. The objective of this paper is to search and analyze articles in the healthcare field where user-centered design principles have been applied. We describe findings in this topic from articles published between January 1995 and September 2014.

  5. Quality assurance manual: Volume 2, Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Oijala, J.E.

    1988-06-01

    This paper contains quality assurance information on departments of the Stanford Linear Accelerator Center. Particular quality assurance policies and standards discussed are on: Mechanical Systems; Klystron and Microwave Department; Electronics Department; Plant Engineering; Accelerator Department; Purchasing; and Experimental Facilities Department. (LSP)

  6. 76 FR 60507 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-29

    ....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, Small Business: Diabetes... Special Emphasis Panel, Fellowship: Genes, Genomes, and Genetics. Date: October 26, 2011. Time: 11 a.m....

  7. 78 FR 64507 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-10-29

    ...; Fellowships: Genes, Genomes and Genetics. Date: November 5-6, 2013. Time: 8:30 a.m. to 1:00 p.m. Agenda: To...: Center for Scientific Review Special Emphasis Panel; Diabetes and Metabolism. Date: November 6,...

  8. 75 FR 11895 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-12

    ... Committee: Center for Scientific Review Special Emphasis Panel, Neural Processing and Social Stress. Date.... Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. BILLING CODE 4140-01-P...

  9. 78 FR 38998 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-06-28

    ...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Oral Microbiology, Oral Pathology and Tooth Mobility. Date: July 25, 2013. Time: 12:00 p.m. to 2:00 p.m. Agenda:...

  10. 78 FR 11211 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-15

    ...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Genomics, Molecular Evolution and Biochemical Genetics. Date: March 7, 2013. Time: 12:00 p.m. to 3:00 p.m. Agenda:...

  11. 78 FR 9404 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-08

    ...-254-9975, helmersk@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis... Rockledge Drive, Room 3166, MSC 7770, Bethesda, MD 20892, 301-254-9975, helmersk@csr.nih.gov . Name...

  12. 78 FR 1864 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-09

    ..., MD 20814. Contact Person: Michael Knecht, Ph.D., Scientific Review Officer, Center for Scientific... Monica Hotel, 530 West Pico Boulevard, Santa Monica, CA 90405. Contact Person: John Bishop,...

  13. 76 FR 7868 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-11

    ... Emphasis Panel, Quick Trial on Imaging and Image-Guided Intervention. Date: March 10, 2011. Time: 1 p.m. to...: Center for Scientific Review Special Emphasis Panel, Member Conflict: Biological Chemistry...

  14. 75 FR 61507 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-10-05

    ... Emphasis Panel, Member Conflicts: Cardiac Ion Channels. Date: October 21, 2010. Time: 2 p.m. to 4 p.m... Committee: Center for Scientific Review Special Emphasis Panel, Analysis of Retinal Diseases. Date:...

  15. 75 FR 4092 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-26

    ... Panel, Member Conflict: Basic Immunology, Vaccine, and Host Defense. Date: February 24, 2010. Time: 9:30... Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict: Cancer Biomarkers....

  16. 76 FR 53479 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-26

    ... grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue.... to 5 p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M...

  17. 76 FR 30734 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-26

    ... Committee: Center for Scientific Review Special Emphasis Panel, Fellowships: Sensory, Motor, and Cognitive... Special Emphasis Panel, Small Business: Drug Discovery and Development. Date: June 23-24, 2011. Time: 7...

  18. 78 FR 58547 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-24

    ... Committee: Center for Scientific Review Special Emphasis Panel; Neurobiology, genetics, stress and mood... Panel; Small Business: Non-HIV Microbial Vaccine Development. Date: October 18, 2013. Time: 8:00 a.m....

  19. BOOK REVIEWS, Centering the Margin, Agency and Narrative in Southeast Asian Borderlands

    OpenAIRE

    Ibrahim Sirkeci

    2007-01-01

    BOOK REVIEW Centering the Margin, Agency and Narrative in Southeast Asian Borderlands Alexander Horstmann and Reed L. Wadley (eds.)(2006) Berghahn Books, New York, Oxford, (ISBN 1-84545-019-1, hardcover)

  20. Software Assurance Using Structured Assurance Case Models.

    Science.gov (United States)

    Rhodes, Thomas; Boland, Frederick; Fong, Elizabeth; Kass, Michael

    2010-01-01

    Software assurance is an important part of the software development process to reduce risks and ensure that the software is dependable and trustworthy. Software defects and weaknesses can often lead to software errors and failures and to exploitation by malicious users. Testing, certification and accreditation have been traditionally used in the software assurance process to attempt to improve software trustworthiness. In this paper, we examine a methodology known as a structured assurance model, which has been widely used for assuring system safety, for its potential application to software assurance. We describe the structured assurance model and examine its application and use for software assurance. We identify strengths and weaknesses of this approach and suggest areas for further investigation and testing.

  1. A Management Review and Analysis of Purdue University Libraries and Audio-Visual Center.

    Science.gov (United States)

    Baaske, Jan; And Others

    A management review and analysis was conducted by the staff of the libraries and audio-visual center of Purdue University. Not only were the study team and the eight task forces drawn from all levels of the libraries and audio-visual center staff, but a systematic effort was sustained through inquiries, draft reports and open meetings to involve…

  2. Quality Assurance - Construction

    DEFF Research Database (Denmark)

    Gaarslev, Axel

    1996-01-01

    Gives contains three main chapters:1. Quality Assurance initiated by external demands2. Quality Assurance initiated by internal company goals3. Innovation strategies......Gives contains three main chapters:1. Quality Assurance initiated by external demands2. Quality Assurance initiated by internal company goals3. Innovation strategies...

  3. 78 FR 66018 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-11-04

    ...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, Accelerator Mass Spectrometry Facility. Date: December 2-3, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and...

  4. 78 FR 50066 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-08-16

    ..., fitzsimmonss@csr.nih.gov . Name of Committee: Risk, Prevention and Health Behavior Integrated Review Group..., Room 3114, MSC 7808, Bethesda, MD 20892, 301-451-9956, fitzsimmonss@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; PAR Panel: Translational Research in Pediatric...

  5. 78 FR 7438 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-01

    ..., Bethesda, MD 20892, 301-435-6809, beheraak@csr.nih.gov . Name of Committee: Center for Scientific Review..., 6701 Rockledge Drive, Room 3182, MSC 7770, Bethesda, MD 20892, 301-435- 0913, mark.lindner@csr.nih.gov... Ethical Issues in Research. Date: February 27, 2013. Time: 2:00 p.m. to 3:00 p.m. Agenda: To review...

  6. 77 FR 16248 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-03-20

    ... Research. Date: April 9-10, 2012. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications...-1166, roebuckk@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: AIDS and AIDS Related Research. Date: April 9-10, 2012. Time: 9 a.m. to 5 p.m....

  7. 77 FR 29673 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-18

    ...: Biobehavioral and Behavioral Processes Integrated Review Group; Biobehavioral Mechanisms of Emotion, Stress and... . Name of Committee: Center for Scientific Review Special Emphasis Panel; PA:12-006: Academic Research... Special Emphasis Panel; PAR10-169: Academic Industrial Partnership. Date: June 14, 2012. Time: 12:00...

  8. 75 FR 27351 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-14

    ... America Hotel, 500 South Main Street, Salt Lake City, UT 84101. Contact Person: Lee Rosen, PhD, Scientific... Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: George M...) Contact Person: George M Barnas, PhD, Scientific Review Officer, Center for Scientific Review,...

  9. 77 FR 60706 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-04

    ... Committee: Center for Scientific Review Special Emphasis Panel, PAR Panel: Social Network Analysis and...: Sensory Technologies. Date: November 1-2, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and... Emphasis Panel, Member Conflict: Healthcare Delivery Methodologies. Date: November 1, 2012. Time: 8:00...

  10. 78 FR 57866 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-20

    ... Committee: Infectious Diseases and Microbiology Integrated Review Group; Virology--B Study Section. Date...: Center for Scientific Review Special Emphasis Panel; Pathophysiology and Clinical Studies of... Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337,...

  11. Mental Health Services in School-Based Health Centers: Systematic Review

    Science.gov (United States)

    Bains, Ranbir Mangat; Diallo, Ana F.

    2016-01-01

    Mental health issues affect 20-25% of children and adolescents, of which few receive services. School-based health centers (SBHCs) provide access to mental health services to children and adolescents within their schools. A systematic review of literature was undertaken to review evidence on the effectiveness of delivery of mental health services…

  12. 75 FR 26261 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-11

    ... Integrated Review Group; Cellular Aspects of Diabetes and Obesity Study Section. Date: June 3-4, 2010. Time..., schwarte@csr.nih.gov . Name of Committtee: Center for Scientific Review Special Emphasis Panel; Nursing and... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306,...

  13. 76 FR 53688 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-29

    ... 2 p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street... p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street, NW... applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda,...

  14. 78 FR 30930 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-23

    ... Committee: Center for Scientific Review Special Emphasis Panel; PAR10-169: Academic Industrial Partnership... Review Special Emphasis Panel; PAR-13-008: Shared Instrumentation: Miscellaneous. Date: June 19-20, 2013... Panel; Small Business: Biomedical Sensing, Measurement and Instrumentation. Date: June 21, 2013. Time:...

  15. 77 FR 28889 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-16

    ... Committee: Center for Scientific Review Special Emphasis Panel; Behavioral Genetics and Epidemiology... Control Revision Applications: Behavioral Genetics and Epidemiology. Date: June 4, 2012. Time: 4:00 p.m...: Behavioral Genetics and Epidemiology. Date: June 4, 2012. Time: 4:00 p.m. to 6:00 p.m. Agenda: To review...

  16. 77 FR 28397 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2012-05-14

    ..., williamsdl2@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, Dental Biomechanics and Implants. Date: June 7, 2012. Time: 3:00 p.m. to 5:00 p.m. Agenda: To review and...

  17. 78 FR 26642 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-07

    ...:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  18. 76 FR 47595 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-05

    ... Hotel, 2660 Woodley Road, NW., Washington, DC 20008. Contact: Xiang-Ning Li, MD, PhD, Scientific Review... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed...

  19. 75 FR 22412 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-28

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Bioengineering Sciences & Technologies Integrated Review Group; Biomaterials and Biointerfaces...: Gastrointestinal Physiology and Pathophysiology. Date: May 28, 2010. Time: 12 p.m. to 2:30 p.m. Agenda: To...

  20. 75 FR 60763 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-10-01

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Healthcare Delivery and Methodologies Integrated Review Group, Biostatistical Methods and...: Physiology and Pathobiology of Cardiovascular and Respiratory Systems. Date: November 18-19, 2010. Time: 8...

  1. 78 FR 6125 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-29

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... . Name of Committee: Digestive, Kidney and Urological Systems Integrated Review Group; Urologic and Genitourinary Physiology and Pathology. Date: February 25, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To...

  2. 78 FR 54258 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-03

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings...: Kidney Physiology and Pathophysiology. Date: September 23, 2013. Time: 1:00 p.m. to 4:30 p.m. Agenda: To... Systems Integrated Review Group; Clinical, Integrative and Molecular Gastroenterology Study Section....

  3. 76 FR 34716 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-14

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: AIDS and Related Research Integrated Review Group, NeuroAIDS and other End-Organ Diseases Study...: Skeletal Muscle and Exercise Physiology. Date: July 13, 2011. Time: 1 p.m. to 3:30 p.m. Agenda: To...

  4. 77 FR 57571 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-18

    ... HUMAN SERVICES National Institutes of Health Center For Scientific Review; Notice of Closed Meetings... . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group; Integrative Physiology of Obesity and Diabetes Study Section. Date: October 18-19, 2012. Time:...

  5. 75 FR 1397 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-11

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Molecular, Cellular and Developmental Neuroscience Integrated Review Group; Molecular... Special Emphasis Panel; Muscle Physiology and Diseases. Date: February 10, 2010. Time: 11 a.m. to 4...

  6. 77 FR 63842 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-17

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: AIDS and Related Research Integrated Review Group; HIV/AIDS Vaccines Study Section. Date...: Physiology and Pathobiology of Musculoskeletal, Oral, and Skin Systems. Date: November 15, 2012. Time: 8:00...

  7. 76 FR 4928 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-27

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Emerging Technologies and Training Neurosciences Integrated Review Group, Molecular Neurogenetics...: Asthma, Lung Immunology, and Lung Physiology. Date: February 23, 2011. Time: 1 p.m. to 5 p.m. Agenda:...

  8. 75 FR 32955 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-10

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Integrated Review Group; AIDS Clinical Studies and Epidemiology Study Section. Date: July 6, 2010. Time: 8 a... Emphasis Panel; Fellowships: Physiology and Pathobiology of Musculoskeletal, Oral, and Skin Systems....

  9. 78 FR 13364 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-27

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings...: Liver and Gastrointestinal Physiology, Pathology and Pharmacology. Date: March 21, 2013. Time: 2:00 p.m... . Name of Committee: AIDS and Related Research Integrated Review Group; AIDS-associated...

  10. 76 FR 55929 - CENTER FOR SCIENTIFIC REVIEW; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-09

    ... Therapeutics Study Section. Date: September 26-27, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate....nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Cancer Therapeutics... and Molecular Pharmacology Study Section. Date: October 10-11, 2011. Time: 8 a.m. to 5 p.m. Agenda:...

  11. Ontario's Quality Assurance Framework: A Critical Response

    Science.gov (United States)

    Heap, James

    2013-01-01

    Ontario's Quality Assurance Framework (QAF) is reviewed and found not to meet all five criteria proposed for a strong quality assurance system focused on student learning. The QAF requires a statement of student learning outcomes and a method and means of assessing those outcomes, but it does not require that data on achievement of intended…

  12. Real-Time Pretreatment Review Limits Unacceptable Deviations on a Cooperative Group Radiation Therapy Technique Trial: Quality Assurance Results of RTOG 0933

    Energy Technology Data Exchange (ETDEWEB)

    Gondi, Vinai, E-mail: vgondi@chicagocancer.org [Cadence Brain Tumor Center and CDH Proton Center, Warrenville, Illinois (United States); University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin (United States); Cui, Yunfeng [Duke University School of Medicine, Durham, North Carolina (United States); Mehta, Minesh P. [University of Maryland School of Medicine, Baltimore, Maryland (United States); Manfredi, Denise [Radiation Therapy Oncology Group—RTQA, Philadelphia, Pennsylvania (United States); Xiao, Ying; Galvin, James M. [Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (United States); Rowley, Howard [University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin (United States); Tome, Wolfgang A. [Montefiore Medical Center and Institute for Onco-Physics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York (United States)

    2015-03-01

    Purpose: RTOG 0933 was a phase II trial of hippocampal avoidance during whole brain radiation therapy for patients with brain metastases. The results demonstrated improvement in short-term memory decline, as compared with historical control individuals, and preservation of quality of life. Integral to the conduct of this trial were quality assurance processes inclusive of pre-enrollment credentialing and pretreatment centralized review of enrolled patients. Methods and Materials: Before enrolling patients, all treating physicians and sites were required to successfully complete a “dry-run” credentialing test. The treating physicians were credentialed based on accuracy of magnetic resonance imaging–computed tomography image fusion and hippocampal and normal tissue contouring, and the sites were credentialed based on protocol-specified dosimetric criteria. Using the same criteria, pretreatment centralized review of enrolled patients was conducted. Physicians enrolling 3 consecutive patients without unacceptable deviations were permitted to enroll further patients without pretreatment review, although their cases were reviewed after treatment. Results: In all, 113 physicians and 84 sites were credentialed. Eight physicians (6.8%) failed hippocampal contouring on the first attempt; 3 were approved on the second attempt. Eight sites (9.5%) failed intensity modulated radiation therapy planning on the first attempt; all were approved on the second attempt. One hundred thirteen patients were enrolled in RTOG 0933; 100 were analyzable. Eighty-seven cases were reviewed before treatment; 5 (5.7%) violated the eligibility criteria, and 21 (24%) had unacceptable deviations. With feedback, 18 cases were approved on the second attempt and 2 cases on the third attempt. One patient was treated off protocol. Twenty-two cases were reviewed after treatment; 1 (4.5%) violated the eligibility criteria, and 5 (23%) had unacceptable deviations. Conclusions: Although >95% of the

  13. 77 FR 63845 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-17

    ...: Dermatology, Rheumatology and Inflammation. Date: November 9, 2012. Time: 8:00 a.m. to 6:00 p.m. Agenda: To... Preventing HIV/ AIDS Study Section. Date: November 8-9, 2012. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review.... Contact Person: Jose H Guerrier, Ph.D., Scientific Review Officer, Center for Scientific Review,...

  14. Quality Assurance: One School's Response.

    Science.gov (United States)

    Wittemann, K. Joseph

    1990-01-01

    Since 1987, the Virginia Commonwealth University School of Dentistry has established a system of committee responsibilities for quality assurance, involving the committees for clinical affairs, academic performance, safety and therapeutics, and a council composed largely of department chairs. Additional review of procedures and records management…

  15. Optical metrology at the Optical Sciences Center: an historical review

    Science.gov (United States)

    Creath, Katherine; Parks, Robert E.

    2014-10-01

    The Optical Sciences Center (OSC) begun as a graduate-level applied optics teaching institution to support the US space effort. The making of optics representative of those used in other space programs was deemed essential. This led to the need for optical metrology: at first Hartmann tests, but almost immediately to interferometric tests using the newly invented HeNe laser. Not only were new types of interferometers needed, but the whole infrastructure that went with testing, fringe location methods, aberration removal software and contour map generation to aid the opticians during polishing needed to be developed. Over the last half century more rapid and precise methods of interferogram data reduction, surface roughness measurement, and methods of instrument calibration to separate errors from those in the optic have been pioneered at OSC. Other areas of research included null lens design and the writing of lens design software that led into the design of computer generated holograms for asphere testing. More recently work has been done on the reduction of speckle noise in interferograms, methods to test large convex aspheres, and a return to slope measuring tests to increase the dynamic range of the types of aspheric surfaces amenable to optical testing including free-form surfaces. This paper documents the history of the development of optical testing projects at OSC and highlights the contributions some of the individuals associated with new methods of testing and the infrastructure needed to support the testing. We conclude with comments about the future trends optical metrology.

  16. 对等代码复杰过程中的质量保证:一个基于计算机科学的策略%Quality Assurance of Peer Code Review Process: A Computer Science Based Strategy

    Institute of Scientific and Technical Information of China (English)

    王延青; 杨发; 刘培杰; COLLINS Michael

    2007-01-01

    The software industry is asking universities and colleges to cultivate more software engineers who can write quality programs. A peer code review process is an ideal approach to maximize the learning outcome of students in programming. In this paper, the process in our previous publication was improved. The found problems were analyzed which will take as the basis of the future research on quality assurance. Finally, a set of solutions based on computer science were proposed to further improve the whole review process.

  17. Internal Quality Assurance System and Its Implementation in Kaunas College

    Science.gov (United States)

    Misiunas, Mindaugas

    2007-01-01

    The article discusses the internal system of quality assurance and its implementation methods in Kaunas College. The issues of quality assurance are reviewed in the context of the European higher education area covering the three levels: European, national and institutional. The importance of quality assurance and its links with external…

  18. Multinational Quality Assurance

    Science.gov (United States)

    Kinser, Kevin

    2011-01-01

    Multinational colleges and universities pose numerous challenges to the traditional models of quality assurance that are designed to validate domestic higher education. When institutions cross international borders, at least two quality assurance protocols are involved. To guard against fraud and abuse, quality assurance in the host country is…

  19. FESA Quality Assurance

    CERN Document Server

    CERN. Geneva

    2015-01-01

    FESA is a framework used by 100+ developers at CERN to design and implement the real-time software used to control the accelerators. Each new version must be tested and qualified to ensure that no backward compatibility issues have been introduced and that there is no major bug which might prevent accelerator operations. Our quality assurance approach is based on code review and a two-level testing process. The first level is made of unit-test (Python unittest & Google tests for C++). The second level consists of integration tests running on an isolated test environment. We also use a continuous integration service (Bamboo) to ensure the tests are executed periodically and the bugs caught early. In the presentation, we will explain the reasons why we took this approach, the results and some thoughts on the pros and cons.

  20. Construction quality assurance report

    Energy Technology Data Exchange (ETDEWEB)

    Roscha, V.

    1994-09-08

    This report provides a summary of the construction quality assurance (CQA) observation and test results, including: The results of the geosynthetic and soil materials conformance testing. The observation and testing results associates with the installation of the soil liners. The observation and testing results associated with the installation of the HDPE geomembrane liner systems. The observation and testing results associated with the installation of the leachate collection and removal systems. The observation and testing results associated with the installation of the working surfaces. The observation and testing results associated with in-plant manufacturing process. Summary of submittal reviews by Golder Construction Services, Inc. The submittal and certification of the piping material specifications. The observation and verification associated of the Acceptance Test Procedure results of the operational equipment functions. Summary of the ECNs which are incorporated into the project.

  1. Construction and Thinking on Security Assurance System in Public Health Data Center%r公共卫生数据中心安全保障体系建设与思考

    Institute of Scientific and Technical Information of China (English)

    肖革新; 张烨; 张睿; 王俊玲

    2012-01-01

    分析中国疾控中心数据中心信息化建设现状及信息安全保障体系存在的问题,对此提出总体应对框架,即构建以公共卫生业务系统为服务对象、安全管理体系建设为龙头、安全技术体系为基础的安全体系结构,为公共卫生数据中心信息安全保障体系建设提供借鉴。%The paper analyzes the informatization construction status of China CDC data center and the existing problems of information security assurance system, puts forwards corresponding framework, namely, constructing the security architecture taking public health service system as a target, system security management system as the leading, security technology system as the basis, so as to provide some references for public health data center information security protection system.

  2. 77 FR 31029 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-24

    ...; Neuroimmunology, Multiple Sclerosis, Alzheimer's Disease, and Sleep Apnea and Restless Leg Syndrome. Date: June 20.... Edwards, Ph.D., IRG Chief, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5210, MSC 7846, Bethesda, MD 20892, (301) 435-1246, edwardss@csr.nih.gov . Name of...

  3. 77 FR 14406 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-03-09

    ... 5216, MSC 7852, Bethesda, MD 20892, 301-435- 1050, freundr@csr.nih.gov . This notice is being published... 20892, 301-435-1038, remondid@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Small Business: HIV/AIDS Innovative Research Applications. Date: March 28, 2012. Time: 1...

  4. 76 FR 81953 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-12-29

    ..., Room 5118, MSC 7854, Bethesda, MD 20892, (301) 435- 2598, firrellj@csr.nih.gov . Name of Committee... 20892, (301) 435-1727, schneidd@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel, RFA Panel: Fogarty International Research Training and Planning Awards (NCD-LIFESPAN)....

  5. 78 FR 78372 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-12-26

    ... 20892, (301) 435-1725, bowersj@csr.nih.gov . This notice is being published less than 15 days prior to...@csr.nih.gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Program Project: Research Resources Reverse Site Visit. Date: January 21-23, 2014. Time: 7:00 p.m. to 12:30 p.m. Agenda:...

  6. 76 FR 63314 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2011-10-12

    ... Panel, Neurologic Disorders and Development. Date: November 3, 2011. Time: 2 p.m. to 4 p.m. Agenda: To... Special Emphasis Panel, Small Business: Biobehavioral and Behavioral Processes across the Lifespan. Date...: Center for Scientific Review Special Emphasis Panel, Small Business: Cancer Development and...

  7. 78 FR 10186 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-13

    ... Special Emphasis Panel; RFA: EY 13-001 Basic Behavioral Research on Multisensory Processing Date: March 7....gov . Name of Committee: Center for Scientific Review Special Emphasis Panel; Fellowships: Cell Biology, Developmental Biology and Bioengineering. Date: March 7, 2013. Time: 8:00 a.m. to 6:00...

  8. 77 FR 11138 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-24

    ... Committee: Center for Scientific Review Special Emphasis Panel; Fellowship: Cell Biology and Development... Special Emphasis Panel; Small Business: Basic and Integrative Bioengineering. Date: March 21, 2012. Time...; RFA Panel: Developmental System Biology. Date: March 22-23, 2012. Time: 8 a.m. to 5:30 p.m. Agenda:...

  9. 78 FR 42968 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-07-18

    ... Committee: Center for Scientific Review Special Emphasis Panel; RFA: Pilot Projects on Sports-Related Brain... Emphasis Panel; Brain and Eye Disorders. Date: August 12, 2013. Time: 1:00 p.m. to 3:00 p.m. Agenda:...

  10. 76 FR 66075 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-10-25

    ... Special Emphasis Panel, DA-12-004: The Placebo Effect: Mechanisms and Methodology (R21). Date: November 30...: Center for Scientific Review Special Emphasis Panel, DA-12-003: The Placebo Effect: Mechanisms and....gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine;...

  11. Games Centered Approaches in Teaching Children & Adolescents: Systematic Review of Associated Student Outcomes

    Science.gov (United States)

    Miller, Andrew

    2015-01-01

    The purpose of this systematic review was to investigate the weight of scientific evidence regarding student outcomes (physical, cognitive and affective) of a Game Centered Approach (GCA) when the quality of a study was taken into account in the interpretation of collective findings. A systematic search of five electronic databases (Sports…

  12. 75 FR 56115 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-15

    .... Gregory Hotel, 2033 M Street, NW., Washington, DC 20036 Contact Person: Ai-Ping Zou, MD, PhD, Scientific.... Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street, NW... Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. Contact...

  13. 77 FR 37425 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-21

    ..., 2033 M Street NW., Washington, DC 20036. Contact Person: Mark P Rubert, Ph.D., Scientific Review... Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Kenneth M... and evaluate grant applications. Place: St Gregory Hotel, 2033 M Street Northwest, Washington,...

  14. 75 FR 27793 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-18

    ... applications. Place: St. Gregory Hotel, 2033 M Street, NW., Washington, DC 20036. Contact Person: Sally A... evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin...: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: St. Gregory Hotel, 2033...

  15. Child-Centered Play Therapy in the Schools: Review and Meta-Analysis

    Science.gov (United States)

    Ray, Dee C.; Armstrong, Stephen A.; Balkin, Richard S.; Jayne, Kimberly M.

    2015-01-01

    The authors conducted a meta-analysis and systematic review that examined 23 studies evaluating the effectiveness of child centered play therapy (CCPT) conducted in elementary schools. Meta-analysis results were explored using a random effects model for mean difference and mean gain effect size estimates. Results revealed statistically significant…

  16. 78 FR 66946 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 17, 2013, 08:00 a.m. to October 17, 2013, 05:00 p.m., Pier 5 Hotel, 711 Eastern...

  17. 76 FR 30179 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2011-05-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Study Section, June 8, 2011, 8 a.m. to June 8, 2011, 6 p.m., Sir Francis Drake Hotel, 450 Powell...

  18. 75 FR 2878 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2010-01-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting..., February 11, 2010, 8 a.m. to February 12, 2010, 5 p.m., Sheraton Fisherman's Wharf Hotel, 2500 Mason...

  19. 78 FR 65349 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 8, 2013, 8:00 a.m. to October 8, 2013, 6:00 p.m., Melrose Hotel, 2430 Pennsylvania...

  20. 78 FR 66372 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-05

    ... FR 54664-54665. The meeting will be held at the Hotel Monaco Baltimore, 2 North Charles Street... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of...

  1. 78 FR 64965 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 17, 2013, 8:00 a.m. to October 17, 2013, 7:00 p.m., Amalfi Hotel, 20 West Kinzie...

  2. 78 FR 64967 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Study Section, October 10, 2013, 08:00 a.m. to October 10, 2013, 06:00 p.m., Doubletree Hotel...

  3. 78 FR 65346 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 21, 2013, 8:00 a.m. to October 21, 2013, 5:00 p.m., Hotel Nikko San Francisco, 222...

  4. 78 FR 64958 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 21, 2013, 8:30 a.m. to October 21, 2013, 3:00 p.m., Amalfi Hotel, 20 West Kinzie...

  5. 78 FR 64963 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting..., October 16, 2013, 08:00 a.m. to October 16, 2013, 06:30 p.m., Washington Plaza Hotel, 10 Thomas...

  6. 78 FR 65344 - Center for Scientific Review Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review Amended Notice of Meeting... Section, October 7, 2013, 8:00 a.m. to October 8, 2013, 12:00 p.m., The Dupont Hotel, 1500 New...

  7. 78 FR 64962 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Hotel, 20 West Kinzie Street, Chicago, IL 60654 which was published in the Federal Register on...

  8. 76 FR 31968 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2011-06-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Study Section, June 8, 2011, 8 a.m. to June 8, 2011, 6 p.m., The Westin St. Francis Hotel, 335...

  9. 78 FR 64961 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ..., 78 FR 55266-55267. The meeting will be held at the Bahia Hotel, 998 W. Mission Bay Drive, San Diego... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of...

  10. 78 FR 66371 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-05

    ..., 2013, 78 FR 187 Pgs. 59361-59362. The meeting will be held at the Renaissance Dupont Circle Hotel, 1143... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of...

  11. 78 FR 64968 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Study Section, October 16, 2013, 8:30 a.m. to October 17, 2013, 1:00 p.m., Avenue Hotel Chicago, 160...

  12. 78 FR 65342 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Section, October 10, 2013, 8:00 a.m. to October 11, 2013, 12:30 p.m., Melrose Hotel, 2430 Pennsylvania...

  13. 78 FR 65347 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting... Hotel, 1143 New Hampshire Avenue NW., Washington, DC 20037 which was published in the Federal...

  14. 78 FR 64959 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-10-30

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting..., October 17, 2013, 8:00 a.m. to October 18, 2013, 2:00 p.m., Sheraton Delfina Santa Monica Hotel, 530...

  15. 78 FR 66031 - Center for Scientific Review; Amended Notice of Meeting

    Science.gov (United States)

    2013-11-04

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Clinical Neuroplasticity and...

  16. 77 FR 30297 - Center for Scientific Review Amended; Notice of Meeting

    Science.gov (United States)

    2012-05-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review Amended; Notice of Meeting Notice is hereby given of a change in the meeting of the Neurotransporters, Receptors, and...

  17. 78 FR 38066 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-06-25

    ... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Panel; Small Business: Digestive Sciences. Date: July 23-24, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda... Emphasis Panel; Fellowships: Physiology and Pathobiology of Cardiovascular and Respiratory. Date: July...

  18. Ocmulgee National Monument Visitor Center solar heating and cooling system design review data

    Energy Technology Data Exchange (ETDEWEB)

    1978-05-01

    This document has been prepared as a part of the detailed design of the solar heating and cooling system to be installed at the Ocmulgee National Monument Visitor Center. It describes the 50 percent design review data for this site, and discusses the design approaches, system trade studies, subsystem design and development approach, solar collectors, preliminary specifications and other related information.

  19. 77 FR 35412 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-13

    ... Panel; Small Business: Non-HIV Infectious Agent Detection/ Diagnostics, Food Safety, Sterilization... Panel; Fellowships: Infectious Diseases and Microbiology. Date: July 12-13, 2012. Time: 8:00 a.m. to 12...: Center for Scientific Review Special Emphasis Panel; AREA: Infectious Diseases and Microbiology....

  20. Quality-assurance and data management plan for groundwater activities by the U.S. Geological Survey in Kansas, 2014

    Science.gov (United States)

    Putnam, James E.; Hansen, Cristi V.

    2014-01-01

    As the Nation’s principle earth-science information agency, the U.S. Geological Survey (USGS) is depended on to collect data of the highest quality. This document is a quality-assurance plan for groundwater activities (GWQAP) of the Kansas Water Science Center. The purpose of this GWQAP is to establish a minimum set of guidelines and practices to be used by the Kansas Water Science Center to ensure quality in groundwater activities. Included within these practices are the assignment of responsibilities for implementing quality-assurance activities in the Kansas Water Science Center and establishment of review procedures needed to ensure the technical quality and reliability of the groundwater products. In addition, this GWQAP is intended to complement quality-assurance plans for surface-water and water-quality activities and similar plans for the Kansas Water Science Center and general project activities throughout the USGS. This document provides the framework for collecting, analyzing, and reporting groundwater data that are quality assured and quality controlled. This GWQAP presents policies directing the collection, processing, analysis, storage, review, and publication of groundwater data. In addition, policies related to organizational responsibilities, training, project planning, and safety are presented. These policies and practices pertain to all groundwater activities conducted by the Kansas Water Science Center, including data-collection programs, interpretive and research projects. This report also includes the data management plan that describes the progression of data management from data collection to archiving and publication.

  1. Bibliometric analysis of poison center-related research published in peer-review journals.

    Science.gov (United States)

    Forrester, M B

    2016-07-01

    Poison centers advance knowledge in the field of toxicology through publication in peer-review journals. This investigation describes the pattern of poison center-related publications. Cases were poison center-related research published in peer-review journals during 1995-2014. These were identified through searching the PubMed database, reviewing the tables of contents of selected toxicology journals, and reviewing abstracts of various national and international meetings. The following variables for each publication were identified: year of publication, journal, type of publication (meeting abstract vs. other, i.e. full article or letter to the editor), and the country(ies) of the poison center(s) included in the research. Of the 3147 total publications, 62.1% were meeting abstracts. There were 263 publications in 1995-1999, 536 in 2000-2004, 999 in 2005-2009, and 1349 in 2010-2014. The publications were in 234 different journals. The journals in which the highest number of research was published were Clinical Toxicology (69.7%), Journal of Medical Toxicology (2.2%), and Veterinary and Human Toxicology (2.1%). The research was reported from 62 different countries. The countries with the highest number of publications were the United States (67.9%), United Kingdom (6.5%), Germany (3.9%), France (2.5%), and Italy (2.4%). The number of publications increased greatly over the 20 years. Although the publications were in a large number of journals, a high proportion of the publications were in one journal. While the research came from a large number of countries, the preponderance came from the United States.

  2. Engaging patients and stakeholders in research proposal review: the patient-centered outcomes research institute.

    Science.gov (United States)

    Fleurence, Rachael L; Forsythe, Laura P; Lauer, Michael; Rotter, Jason; Ioannidis, John P A; Beal, Anne; Frank, Lori; Selby, Joseph V

    2014-07-15

    The inaugural round of merit review for the Patient-Centered Outcomes Research Institute (PCORI) in November 2012 included patients and other stakeholders, as well as scientists. This article examines relationships among scores of the 3 reviewer types, changes in scoring after in-person discussion, and the effect of inclusion of patient and stakeholder reviewers on the review process. In the first phase, 363 scientists scored 480 applications. In the second phase, 59 scientists, 21 patients, and 31 stakeholders provided a "prediscussion" score and a final "postdiscussion" score after an in-person meeting for applications. Bland-Altman plots were used to characterize levels of agreement among and within reviewer types before and after discussion. Before discussion, there was little agreement among average scores given by the 4 lead scientific reviewers and patient and stakeholder reviewers. After discussion, the 4 primary reviewers showed mild convergence in their scores, and the 21-member panel came to a much stronger agreement. Of the 25 awards with the best (and lowest) scores after phase 2, only 13 had ranked in the top 25 after the phase 1 review by scientists. Five percent of the 480 proposals submitted were funded. The authors conclude that patient and stakeholder reviewers brought different perspectives to the review process but that in-person discussion led to closer agreement among reviewer types. It is not yet known whether these conclusions are generalizable to future rounds of peer review. Future work would benefit from additional data collection for evaluation purposes and from long-term evaluation of the effect on the funded research.

  3. Data center network architecture in cloud computing:review, taxonomy, and open research issues

    Institute of Scientific and Technical Information of China (English)

    Han QI; Muhammad SHIRAZ; Jie-yao LIU; Abdullah GANI; Zulkanain ABDUL RAHMAN; Torki AALTAMEEM

    2014-01-01

    The data center network (DCN), which is an important component of data centers, consists of a large number of hosted servers and switches connected with high speed communication links. A DCN enables the deployment of resources centralization and on-demand access of the information and services of data centers to users. In recent years, the scale of the DCN has constantly increased with the widespread use of cloud-based services and the unprecedented amount of data delivery in/between data centers, whereas the traditional DCN architecture lacks aggregate bandwidth, scalability, and cost effectiveness for coping with the increasing demands of tenants in accessing the services of cloud data centers. Therefore, the design of a novel DCN architecture with the features of scalability, low cost, robustness, and energy conservation is required. This paper reviews the recent research fi ndings and technologies of DCN architectures to identify the issues in the existing DCN architectures for cloud computing. We develop a taxonomy for the classifi cation of the current DCN architectures, and also qualitatively analyze the traditional and contemporary DCN architectures. Moreover, the DCN architectures are compared on the basis of the signifi cant characteristics, such as bandwidth, fault tolerance, scalability, overhead, and deployment cost. Finally, we put forward open research issues in the deployment of scalable, low-cost, robust, and energy-efficient DCN architecture, for data centers in computational clouds.

  4. Proceedings of RIKEN BNL Research Center Workshop, Volume 91, RBRC Scientific Review Committee Meeting

    Energy Technology Data Exchange (ETDEWEB)

    Samios,N.P.

    2008-11-17

    The ninth evaluation of the RIKEN BNL Research Center (RBRC) took place on Nov. 17-18, 2008, at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC) were Dr. Dr. Wit Busza (Chair), Dr. Miklos Gyulassy, Dr. Akira Masaike, Dr. Richard Milner, Dr. Alfred Mueller, and Dr. Akira Ukawa. We are pleased that Dr. Yasushige Yano, the Director of the Nishina Institute of RIKEN, Japan participated in this meeting both in informing the committee of the activities of the Nishina Institute and the role of RBRC and as an observer of this review. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation, theoretical, experimental and computational physics. In addition the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN Management (Dr. Ryoji Noyori, RIKEN President) on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.

  5. High assurance services computing

    CERN Document Server

    2009-01-01

    Covers service-oriented technologies in different domains including high assurance systemsAssists software engineers from industry and government laboratories who develop mission-critical software, and simultaneously provides academia with a practitioner's outlook on the problems of high-assurance software development

  6. Building Assured Systems Framework

    Science.gov (United States)

    2010-09-01

    Extraction (FX) Techniques to Reverse Engineer Virtual Machines Mark Pleszkoch, Stacy Prowell, Cory F. Cohen, and Jeffrey S. Havrilla 6.3 Assured...Cory F. Cohen and Jeffrey S. Havrilla 5.1.2 Potential attack methods, 5.2.1 Historic and potential operational attack methods, 6.3 Assured

  7. NASA Goddard Space Flight Center Supply Chain Management Program

    Science.gov (United States)

    Kelly, Michael P.

    2011-01-01

    This slide presentation reviews the working of the Supplier Assessment Program at NASA Goddard Space Flight Center. The program supports many GSFC projects to ensure suppliers are aware of and are following the contractual requirements, to provide an independent assessment of the suppliers' processes, and provide suppliers' safety and mission assurance organizations information to make the changes within their organization.

  8. Quality assurance of metabolomics.

    Science.gov (United States)

    Bouhifd, Mounir; Beger, Richard; Flynn, Thomas; Guo, Lining; Harris, Georgina; Hogberg, Helena; Kaddurah-Daouk, Rima; Kamp, Hennicke; Kleensang, Andre; Maertens, Alexandra; Odwin-DaCosta, Shelly; Pamies, David; Robertson, Donald; Smirnova, Lena; Sun, Jinchun; Zhao, Liang; Hartung, Thomas

    2015-01-01

    Metabolomics promises a holistic phenotypic characterization of biological responses to toxicants. This technology is based on advanced chemical analytical tools with reasonable throughput, including mass-spectroscopy and NMR. Quality assurance, however - from experimental design, sample preparation, metabolite identification, to bioinformatics data-mining - is urgently needed to assure both quality of metabolomics data and reproducibility of biological models. In contrast to microarray-based transcriptomics, where consensus on quality assurance and reporting standards has been fostered over the last two decades, quality assurance of metabolomics is only now emerging. Regulatory use in safety sciences, and even proper scientific use of these technologies, demand quality assurance. In an effort to promote this discussion, an expert workshop discussed the quality assurance needs of metabolomics. The goals for this workshop were 1) to consider the challenges associated with metabolomics as an emerging science, with an emphasis on its application in toxicology and 2) to identify the key issues to be addressed in order to establish and implement quality assurance procedures in metabolomics-based toxicology. Consensus has still to be achieved regarding best practices to make sure sound, useful, and relevant information is derived from these new tools.

  9. Product assurance policies and procedures for flight dynamics software development

    Science.gov (United States)

    Perry, Sandra; Jordan, Leon; Decker, William; Page, Gerald; Mcgarry, Frank E.; Valett, Jon

    1987-01-01

    The product assurance policies and procedures necessary to support flight dynamics software development projects for Goddard Space Flight Center are presented. The quality assurance and configuration management methods and tools for each phase of the software development life cycles are described, from requirements analysis through acceptance testing; maintenance and operation are not addressed.

  10. Incorporating student-centered approaches into catchment hydrology teaching: a review and synthesis

    Directory of Open Access Journals (Sweden)

    S. E. Thompson

    2012-09-01

    Full Text Available As hydrologists confront the future of water resources on a globalized, resource-scarce and human-impacted planet, the educational preparation of future generations of water scientists becomes increasingly important. Although hydrology inherits a tradition of teacher-centered direct instruction – based on lecture, reading and assignment formats – a growing body of knowledge derived from engineering education research suggests that modifications to these methods could firstly improve the quality of instruction from a student perspective, and secondly contribute to better professional preparation of hydrologists, in terms of their abilities to transfer knowledge to new contexts, to frame and solve novel problems, and to work collaboratively in uncertain environments. Here we review the theoretical background and empirical literature relating to adopting student-centered and inductive models of teaching and learning. Models of student-centered learning and their applications in engineering education are introduced by outlining the approaches used by several of the authors to introduce student-centered and inductive educational strategies into their university classrooms. Finally, the relative novelty of research on engineering instruction in general and hydrology in particular creates opportunities for new partnerships between education researchers and hydrologists to explore the discipline-specific needs of hydrology students and develop new approaches for instruction and professional preparation of hydrologists.

  11. Incorporating student-centered approaches into catchment hydrology teaching: a review and synthesis

    Science.gov (United States)

    Thompson, S. E.; Ngambeki, I.; Troch, P. A.; Sivapalan, M.; Evangelou, D.

    2012-09-01

    As hydrologists confront the future of water resources on a globalized, resource-scarce and human-impacted planet, the educational preparation of future generations of water scientists becomes increasingly important. Although hydrology inherits a tradition of teacher-centered direct instruction - based on lecture, reading and assignment formats - a growing body of knowledge derived from engineering education research suggests that modifications to these methods could firstly improve the quality of instruction from a student perspective, and secondly contribute to better professional preparation of hydrologists, in terms of their abilities to transfer knowledge to new contexts, to frame and solve novel problems, and to work collaboratively in uncertain environments. Here we review the theoretical background and empirical literature relating to adopting student-centered and inductive models of teaching and learning. Models of student-centered learning and their applications in engineering education are introduced by outlining the approaches used by several of the authors to introduce student-centered and inductive educational strategies into their university classrooms. Finally, the relative novelty of research on engineering instruction in general and hydrology in particular creates opportunities for new partnerships between education researchers and hydrologists to explore the discipline-specific needs of hydrology students and develop new approaches for instruction and professional preparation of hydrologists.

  12. 42 CFR 441.352 - State assurances.

    Science.gov (United States)

    2010-10-01

    ... medical assistance with respect to NF, home health, private duty nursing, personal care services, home and... 42 Public Health 4 2010-10-01 2010-10-01 false State assurances. 441.352 Section 441.352 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  13. Software quality assurance handbook

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    There are two important reasons for Software Quality Assurance (SQA) at Allied-Signal Inc., Kansas City Division (KCD): First, the benefits from SQA make good business sense. Second, the Department of Energy has requested SQA. This handbook is one of the first steps in a plant-wide implementation of Software Quality Assurance at KCD. The handbook has two main purposes. The first is to provide information that you will need to perform software quality assurance activities. The second is to provide a common thread to unify the approach to SQA at KCD. 2 figs.

  14. Review on space weather in Latin America. 3. Development of space weather forecasting centers

    Science.gov (United States)

    Denardini, Clezio Marcos; Dasso, Sergio; Gonzalez-Esparza, J. Americo

    2016-11-01

    The present work is the third of a three-part review of space weather in Latin America, specifically observing its evolution in three countries (Argentina, Brazil and Mexico). This work presents the decision process for the spinning off of space weather prediction centers from space science groups with our interpretation of the reasons/opportunities that lead to this. Lastly, the constraints for the progress in space weather monitoring, research, and forecast are listed with recommendations to overcome them, which we believe will lead to the access of key variables for the monitoring and forecasting space weather, which will allow these centers to better monitor space weather and issue warnings, ​watches and alerts.

  15. Health consequences of the September 11 World Trade Center attacks: a review.

    Science.gov (United States)

    Moline, Jacqueline; Herbert, Robin; Nguyen, Ngoctram

    2006-01-01

    In the aftermath of the September 11 World Trade Center (WTC) attack, a large number of people sustained potential exposures to smoke, dust, particulate matter, and a variety of toxins, including asbestos, pulverized concrete, glass fibers, polycyclic aromatic hydrocarbons (PAHs), and polychlorinated furans and dioxins. Additionally, many had exposure to psychological traumatogens. The most common effects seen to date are respiratory and mental health consequences. The long-term consequences of exposures are not yet known, and there remains concern about the potential for late-emerging diseases such as cancers. This article reviews WTC-related health effects, the spectrum of exposures and how they were documented, and discusses future preventive efforts.

  16. Performance assurance program plan

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, B.H.

    1997-11-06

    B and W Protec, Inc. (BWP) is responsible for implementing the Performance Assurance Program for the Project Hanford Management Contract (PHMC) in accordance with DOE Order 470.1, Safeguards and Security Program (DOE 1995a). The Performance Assurance Program applies to safeguards and security (SAS) systems and their essential components (equipment, hardware, administrative procedures, Protective Force personnel, and other personnel) in direct support of Category I and H special nuclear material (SNM) protection. Performance assurance includes several Hanford Site activities that conduct performance, acceptance, operability, effectiveness, and validation tests. These activities encompass areas of training, exercises, quality assurance, conduct of operations, total quality management, self assessment, classified matter protection and control, emergency preparedness, and corrective actions tracking and trending. The objective of the Performance Assurance Program is to capture the critical data of the tests, training, etc., in a cost-effective, manageable program that reflects the overall effectiveness of the program while minimizing operational impacts. To aid in achieving this objective, BWP will coordinate the Performance Assurance Program for Fluor Daniel Hanford, Inc. (FDH) and serve as the central point for data collection.

  17. Performance assurance for IT systems

    CERN Document Server

    King, Brian

    2004-01-01

    INDIVIDUAL AREAS OF INTERESTPreparing for the ChallengeAbstractIntroductionIn the BeginningThe Need to Address New ApplicationsDefinition of PerformanceThe Required SkillsPerformance Assurance Within a Project LifecycleSummaryCaveat Emptor (Let the Buyer Beware)AbstractSoftware Product LifecycleHardware Product LifecycleMarketingTechnical Reviews of ProductsLies, Damned Lies and BenchmarksAbstractIntroductionIndustry BenchmarksVendor BenchmarksIndependent BenchmarkingIn-House Benchmarking""Tricks of the Trade""Using Benchmarks Non-Functional Requirements and SolutionsAbstractIntroductionThe Pr

  18. Improving surface and defect center chemistry of fluorescent nanodiamonds for imaging purposes--a review.

    Science.gov (United States)

    Nagl, Andreas; Hemelaar, Simon Robert; Schirhagl, Romana

    2015-10-01

    Diamonds are widely used for jewelry owing to their superior optical properties accounting for their fascinating beauty. Beyond the sparkle, diamond is highly investigated in materials science for its remarkable properties. Recently, fluorescent defects in diamond, particularly the negatively charged nitrogen-vacancy (NV(-)) center, have gained much attention: The NV(-) center emits stable, nonbleaching fluorescence, and thus could be utilized in biolabeling, as a light source, or as a Förster resonance energy transfer donor. Even more remarkable are its spin properties: with the fluorescence intensity of the NV(-) center reacting to the presence of small magnetic fields, it can be utilized as a sensor for magnetic fields as small as the field of a single electron spin. However, a reproducible defect and surface and defect chemistry are crucial to all applications. In this article we review methods for using nanodiamonds for different imaging purposes. The article covers (1) dispersion of particles, (2) surface cleaning, (3) particle size selection and reduction, (4) defect properties, and (5) functionalization and attachment to nanostructures, e.g., scanning probe microscopy tips.

  19. NASA Johnson Space Center's Energy and Sustainability Efforts

    Science.gov (United States)

    Ewert, Michael K.

    2008-01-01

    This viewgraph presentation reviews the efforts that NASA is making to assure a sustainable environment and energy savings at the Johnson Space Center. Sustainability is defined as development that meets the needs of present generations without compromising the ability of future generations to meet their own needs. The new technologies that are required for sustainable closed loop life support for space exploration have uses on the ground to reduce energy, greenhouse gas emissions, and water use. Some of these uses are reviewed.

  20. From quality assurance to total quality management

    OpenAIRE

    Andreea Ionică

    2003-01-01

    Quality assurance is broadly the prevention of quality problems through planned and systematic activities. These will include the establishment of a good quality management system and the assessment of its adequacy, the audit of the operation of the system, and the review of the system itself

  1. Vega flow assurance system

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Marit; Munaweera, Sampath

    2010-07-01

    Vega is a gas condensate field located at the west coast of Norway and developed as a tie-in to the Gjoea platform. Operator is Statoil, production startup is estimated to the end of 2010. Flow assurance challenges are high reservoir pressure and temperature, hydrate and wax control, liquid accumulation and monitoring the well/template production rates. The Vega Flow Assurance System (FAS) is a software that supports monitoring and operation of the field. The FAS is based FlowManagerTM designed for real time systems. This is a flexible tool with its own steady state multiphase- and flow assurance models. Due to the long flowlines lines and the dynamic behavior, the multiphase flow simulator OLGA is also integrated in the system. Vega FAS will be used as: - An online monitoring tool - An offline what-if simulation and validation tool - An advisory control system for well production allocation. (Author)

  2. Quality assurance in diagnostic ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Sipilae, Outi, E-mail: outi.sipila@hus.fi [HUS Helsinki Medical Imaging Center, Helsinki University Central Hospital, P.O. Box 340, 00029 HUS (Finland); Mannila, Vilma, E-mail: vilma.mannila@hus.fi [HUS Helsinki Medical Imaging Center, Helsinki University Central Hospital, P.O. Box 340, 00029 HUS (Finland); Department of Physics, University of Helsinki, P.O. Box 64, 00014 Helsinki University (Finland); Vartiainen, Eija, E-mail: eija.vartiainen@hus.fi [HUS Helsinki Medical Imaging Center, Helsinki University Central Hospital, P.O. Box 750, 00029 HUS (Finland)

    2011-11-15

    Objective: To setup a practical ultrasound quality assurance protocol in a large radiological center, results from transducer tests, phantom measurements and visual checks for physical faults were compared. Materials and methods: Altogether 151 transducers from 54 ultrasound scanners, from seven different manufacturers, were tested with a Sonora FirstCall aPerio{sup TM} system (Sonora Medical Systems, Inc., Longmont, CO, USA) to detect non-functional elements. Phantom measurements using a CIRS General Purpose Phantom Model 040 (CIRS Tissue Simulation and Phantom Technology, VA, USA) were available for 135 transducers. The transducers and scanners were also checked visually for physical faults. The percentages of defective findings in these tests were computed. Results: Defective results in the FirstCall tests were found in 17% of the 151 transducers, and in 16% of the 135 transducers. Defective image quality resulted with 15% of the transducers, and 25% of the transducers had a physical flaw. In 16% of the scanners, a physical fault elsewhere than in the transducer was found. Seven percent of the transducers had a concurrent defective result both in the FirstCall test and in the phantom measurements, 8% in the FirstCall test and in the visual check, 4% in the phantom measurements and in the visual check, and 2% in all three tests. Conclusion: The tested methods produced partly complementary results and seemed all to be necessary. Thus a quality assurance protocol is forced to be rather labored, and therefore the benefits and costs must be closely followed.

  3. Benchmarking Software Assurance Implementation

    Science.gov (United States)

    2011-05-18

    product The chicken#. (a.k.a. Process Focused Assessment ) – Management Systems ( ISO 9001 , ISO 27001, ISO 2000) – Capability Maturity Models (CMMI...Assurance PRM, RMM, Assurance for CMMI)) – Lifecycle Processes ( ISO /IEEE 15288, ISO /IEEE 12207) – COBIT, ITIL, MS SDL, OSAMM, BSIMM 5 The egg...a.k.a Product Focused Assessments) – SCAP - NIST-SCAP – ISO /OMG W3C – KDM, BPMN, RIF, XMI, RDF – OWASP Top 10 – SANS TOP 25 – Secure Code Check Lists

  4. Medicare: a strategy for quality assurance.

    Science.gov (United States)

    Lohr, K N

    1991-01-01

    This paper has outlined a strategy proposed by an IOM study committee for a quality review and assurance program for Medicare. The committee intended that such a program respond to several major issues, including: the burdens of harm of poor quality of care (poor performance of clinicians in both technical and interpersonal ways, unnecessary and inappropriate services, and lack of needed and appropriate services); difficulties and incentives presented by the organization and financing of healthcare; the state of scientific knowledge; the problems of adversarial, punitive, and burdensome external QA activities and the need to foster successful internal, organization-based QA programs; the adequacy of quality review and assurance methods and tools; and the human and financial resources for quality assurance. In comparison with the existing federal peer review organization program, the IOM's proposed program is intended to focus far more directly on quality assurance, cover all major settings of care, emphasize both a wide range of patient outcomes and the process of care, and have a greatly expanded program evaluation component and greater public oversight and accountability. In laying out the details of such a program, the IOM committee advanced 10 recommendations to support its proposed program. Two of these call for the Secretary of DHHS to support and expand research and educational activities designed to improve the nation's knowledge base and capacity for quality assurance. Finally, the committee emphasized both the extraordinary challenges of quality assurance and the diversity of support for addressing those challenges, noting that patients, providers, and societal agents all have a responsibility in this regard. Building the nation's capacity through additional research and expanded educational efforts is a major cornerstone of the entire enterprise.

  5. A review of user-centered design for diabetes-related consumer health informatics technologies.

    Science.gov (United States)

    LeRouge, Cynthia; Wickramasinghe, Nilmini

    2013-07-01

    User-centered design (UCD) is well recognized as an effective human factor engineering strategy for designing ease of use in the total customer experience with products and information technology that has been applied specifically to health care information technology systems. We conducted a literature review to analyze the current research regarding the use of UCD methods and principles to support the development or evaluation of diabetes-related consumer health informatics technology (CHIT) initiatives. Findings indicate that (1) UCD activities have been applied across the technology development life cycle stages, (2) there are benefits to incorporating UCD to better inform CHIT development in this area, and (3) the degree of adoption of the UCD process is quite uneven across diabetes CHIT studies. In addition, few to no studies report on methods used across all phases of the life cycle with process detail. To address that void, the Appendix provides an illustrative case study example of UCD techniques across development stages.

  6. Blood blister-like aneurysms: Single center experience and systematic literature review

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Ana Marcos; Narata, Ana Paula; Yilmaz, Hasan [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland); Bijlenga, Philippe; Radovanovic, Ivan; Schaller, Karl [Service of Neurosurgery, University Hospital of Geneva (Switzerland); Lovblad, Karl-Olof [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland); Pereira, Vitor Mendes, E-mail: vitormpbr@hotmail.com [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland)

    2014-01-15

    Blood blister-like aneurysms (BBAs) are a controversial entity. They arise from non-branching sites on the supraclinoid internal carotid artery (ICA) and are suspected to originate from a dissection. Our aim is to describe the BBA cases seen in our center and to present a systematic review of the literature on BBAs. We analyzed the eleven cases of BBA admitted to our center from 2003 to 2012. We assessed the medical history, treatment modality (endovascular and/or surgery), complications and clinical outcome. The cohort included 8 women and 4 men with a mean age of 53.16 years. Treatment of the BBA consisted of stenting and coiling in 5 patients, stenting only in 4 patients, coiling and clipping in 1 patient, clipping only in 1 patient, and conservative treatment in 1 patient. A good outcome was found in 10 patients, as defined by a modified Rankin Scale (mRS) less than or equal to two at three months. A systematic review of the literature was performed, and 314 reported patients were found: 221 patients were treated with a primarily surgical approach, and 87 patients were treated with a primarily endovascular approach. A rescue or second treatment was required in 46 patients (21%). The overall estimated treatment morbidity rate was 17%, and the mortality rate was 15%. BBAs exhibit more aggressive behavior compared to saccular aneurysms, and more intra-operative complications occur with BBAs, independent of the treatment type offered. They are also significantly more likely to relapse and rebleed after treatment. Endovascular treatment offers a lower morbidity–mortality compared with surgical approaches. Multilayer flow-diverting stents appear to be a promising strategy.

  7. Blood blister-like aneurysms: single center experience and systematic literature review.

    Science.gov (United States)

    Gonzalez, Ana Marcos; Narata, Ana Paula; Yilmaz, Hasan; Bijlenga, Philippe; Radovanovic, Ivan; Schaller, Karl; Lovblad, Karl-Olof; Pereira, Vitor Mendes

    2014-01-01

    Blood blister-like aneurysms (BBAs) are a controversial entity. They arise from non-branching sites on the supraclinoid internal carotid artery (ICA) and are suspected to originate from a dissection. Our aim is to describe the BBA cases seen in our center and to present a systematic review of the literature on BBAs. We analyzed the eleven cases of BBA admitted to our center from 2003 to 2012. We assessed the medical history, treatment modality (endovascular and/or surgery), complications and clinical outcome. The cohort included 8 women and 4 men with a mean age of 53.16 years. Treatment of the BBA consisted of stenting and coiling in 5 patients, stenting only in 4 patients, coiling and clipping in 1 patient, clipping only in 1 patient, and conservative treatment in 1 patient. A good outcome was found in 10 patients, as defined by a modified Rankin Scale (mRS) less than or equal to two at three months. A systematic review of the literature was performed, and 314 reported patients were found: 221 patients were treated with a primarily surgical approach, and 87 patients were treated with a primarily endovascular approach. A rescue or second treatment was required in 46 patients (21%). The overall estimated treatment morbidity rate was 17%, and the mortality rate was 15%. BBAs exhibit more aggressive behavior compared to saccular aneurysms, and more intra-operative complications occur with BBAs, independent of the treatment type offered. They are also significantly more likely to relapse and rebleed after treatment. Endovascular treatment offers a lower morbidity-mortality compared with surgical approaches. Multilayer flow-diverting stents appear to be a promising strategy.

  8. Quality Assurance Source Requirements Traceability Database

    Energy Technology Data Exchange (ETDEWEB)

    MURTHY, R., NAYDENOVA, A., DEKLEVER, R., BOONE, A.

    2006-01-30

    At the Yucca Mountain Project the Project Requirements Processing System assists in the management of relationships between regulatory and national/industry standards source criteria, and Quality Assurance Requirements and Description document (DOE/R W-0333P) requirements to create compliance matrices representing respective relationships. The matrices are submitted to the U.S. Nuclear Regulatory Commission to assist in the commission's review, interpretation, and concurrence with the Yucca Mountain Project QA program document. The tool is highly customized to meet the needs of the Office of Civilian Radioactive Waste Management Office of Quality Assurance.

  9. A review of the design and development processes of simulation for training in healthcare - A technology-centered versus a human-centered perspective.

    Science.gov (United States)

    Persson, Johanna

    2017-01-01

    This article reviews literature about simulation systems for training in healthcare regarding the prevalence of human-centered approaches in the design and development of these systems, motivated by a tradition in this field of working technology-centered. The results show that the focus on human needs and context of use is limited. It is argued that a reduction of the focus on technical advancements in favor of the needs of the users and the healthcare community, underpinned by human factors and ergonomics theory, is favorable. Due to the low number of identified articles describing or discussing human-centered approaches it is furthermore concluded that the publication culture promotes technical descriptions and summative evaluations rather than descriptions and reflections regarding the design and development processes. Shifting the focus from a technology-centered approach to a human-centered one can aid in the process of creating simulation systems for training in healthcare that are: 1) relevant to the learning objectives, 2) adapted to the needs of users, context and task, and 3) not selected based on technical or fidelity criteria.

  10. Safety and Mission Assurance Knowledge Management Retention

    Science.gov (United States)

    Johnson, Teresa A.

    2006-01-01

    This viewgraph presentation reviews the issues surrounding the management of knowledge in regards to safety and mission assurance. The JSC workers who were hired in the 1960's are slated to retire in the next two to three years. The experiences and knowledge of these NASA workers must be identified, and disseminated. This paper reviews some of the strategies that the S&MA is developing to capture that valuable institutional knowledge.

  11. Mission Operations Assurance

    Science.gov (United States)

    Faris, Grant

    2012-01-01

    Integrate the mission operations assurance function into the flight team providing: (1) value added support in identifying, mitigating, and communicating the project's risks and, (2) being an essential member of the team during the test activities, training exercises and critical flight operations.

  12. Transanal surgery for obstructed defecation syndrome: Literature review and a single-center experience

    Science.gov (United States)

    Liu, Wei-Cheng; Wan, Song-Lin; Yaseen, SM; Ren, Xiang-Hai; Tian, Cui-Ping; Ding, Zhao; Zheng, Ken-Yan; Wu, Yun-Hua; Jiang, Cong-Qing; Qian, Qun

    2016-01-01

    Obstructed defecation syndrome (ODS) is a functional disorder commonly encountered by colorectal surgeons and gastroenterologists, and greatly affects the quality of life of patients from both societal and psychological aspects. The underlying anatomical and pathophysiological changes of ODS are complex. However, intra-rectal intussusception and rectocele are frequently found in patients with ODS and both are thought to play an important role in the pathogenesis of ODS. With the development of evaluation methods in anorectal physiology laboratories and radiology studies, a great variety of new operative procedures, especially transanal procedures, have been invented to treat ODS. However, no procedure has been proved to be superior to others at present. Each operation has its own merits and defects. Thus, choosing appropriate transanal surgical procedures for the treatment of ODS remains a challenge for all surgeons. This review provides an introduction of the current problems and options for treatment of ODS and a detailed summary of the essential assessments needed for patient evaluation before carrying out transanal surgery. Besides, an overview of the benefits and problems of current transanal surgical procedures for treatment of ODS is summarized in this review. A report of clinical experience of some transanal surgical techniques used in the authors’ center is also presented. PMID:27672293

  13. Turner syndrome: review of clinical, neuropsychiatric, and EEG status: an experience of tertiary center.

    Science.gov (United States)

    Saad, Khaled; Abdelrahman, Ahmed A; Abdel-Raheem, Yasser F; Othman, Essam R; Badry, Reda; Othman, Hisham A K; Sobhy, Karema M

    2014-03-01

    We reviewed the clinical, neuropsychiatric, and EEG status of 53 turner syndrome (TS) females, aged 3-16 years, in Assiut university hospitals, Upper Egypt. The diagnosis and care of patients with TS in Egypt is still in the developing stage. Hence this study was undertaken to review the details of patients with TS with respect to the pattern of cognitive, psychiatric, and motor dysfunction. We aimed to provide a comprehensive data about the experience of our center comparable to previous studies, which have been published in this field. This will contribute to a better definition of the neuropsychiatric features that may be specific to TS that allows early and better detection and management of these cases. We found FSIQ and verbal IQ that seem to be at a nearly normal level and a decreased performance IQ. ADHD and autistic symptoms were found in 20.70 and 3.77 % of our cohort, respectively. The motor performance in TS was disturbed, with some neurological deficits present in 17 % (reduced muscle tone and reduced muscle power). In addition, females with TS in our study exhibit social and emotional problems, including anxiety (5.66 %) and depression (11.30 %). The EEG results revealed abnormalities in seven patients (13.20 %). One patient presenting with generalized tonic-clonic seizures showed generalized epileptiform activity, and six patients presenting with intellectual disabilities showed abnormal EEG background activity.

  14. Quality assurance for gamma knives

    Energy Technology Data Exchange (ETDEWEB)

    Jones, E.D.; Banks, W.W.; Fischer, L.E. [Lawrence Livermore National Lab., CA (United States)

    1995-09-01

    This report describes and summarizes the results of a quality assurance (QA) study of the Gamma Knife, a nuclear medical device used for the gamma irradiation of intracranial lesions. Focus was on the physical aspects of QA and did not address issues that are essentially medical, such as patient selection or prescription of dose. A risk-based QA assessment approach was used. Sample programs for quality control and assurance are included. The use of the Gamma Knife was found to conform to existing standards and guidelines concerning radiation safety and quality control of external beam therapies (shielding, safety reviews, radiation surveys, interlock systems, exposure monitoring, good medical physics practices, etc.) and to be compliant with NRC teletherapy regulations. There are, however, current practices for the Gamma Knife not covered by existing, formalized regulations, standards, or guidelines. These practices have been adopted by Gamma Knife users and continue to be developed with further experience. Some of these have appeared in publications or presentations and are slowly finding their way into recommendations of professional organizations.

  15. Creating Quality Assurance and International Transparency for Quality Assurance Agencies

    DEFF Research Database (Denmark)

    Kristoffersen, Dorte; Lindeberg, Tobias

    2004-01-01

    The paper presents the experiences gained in the pilot project on mutual recognition conducted by the quality assurance agencies in the Nordic countries and the future perspective for international quality assurance of national quality assurance agencies. The background of the project was the need......, on the one hand, to advance internationalisation of quality assurance of higher education, and on the other hand, allow for the differences in the national approaches to quality assurance. The paper will focus on two issues: first, the strength and weaknesses of the method employed and of the use of the ENQA...

  16. Quality Assurance: Strategic Choices for Higher Education in Turkey

    Directory of Open Access Journals (Sweden)

    Mahmut ÖZER

    2011-01-01

    Full Text Available As the number of students and higher education institutions in the world increases and there is a growing difficulty in financing the higher education systems, decision-makers have begun to show more interest in quality assurance. As quality assurance is given special attention in European countries, developing countries such as Turkey are interested in importing quality assurance systems. It is not possible to set quality assurance without sensitivity toward quality and without having quality as a cultural practice. The most likely encountered quality assurance approach in the world is that the higher education institution itself is responsible for its quality. In addition, external quality assurance procedures used are based on (academic peer review rather than on bureaucratic evaluations. Moreover, there is a lively debate across the world regarding the bureaucratic regulations of the quality assurance agencies and institutions that restrict the autonomy of higher education institutions. Without taking into consideration of the existing centralized structure of the higher education system in Turkey, of meeting social demands for the higher education, and of current higher education enrollment rates, the possible establishment of a quality assurance mechanism that may have sanctions on universities in Turkey is a threat to already limited autonomy of universities and is having a risk of additional bureaucratic burden. By laying out the roles and responsibilities of Turkish Council of Higher Education, the government and universities, this article discusses policies that should be adopted regarding the quality assurance.

  17. [Medical quality assurance today].

    Science.gov (United States)

    Schäfer, Robert D

    2008-01-01

    Both the quality and performance of health systems are strongly influenced by the number and the qualification of the professional staff. Quality assurance programs help to analyse causalities which are responsible for medical malpractice. On the basis of the experiences gained by the performance of established Quality Assurance Programs (QAP) in the North Rhine area since 1982 various aspects of the efficiency of these programs will be discussed. The implementation of legal regulations making these programs mandatory is criticised not only for its bureaucratic effect but also for the attempt to exclude professional experts from the interpretation of results. It is recommended to liberalize these regulations in order to facilitate improvement of methods and participation of the medical profession.

  18. Current Practices in Constructing and Evaluating Assurance Cases With Applications to Aviation

    Science.gov (United States)

    Rinehart, David J.; Knight, John C.; Rowanhill, Jonathan

    2015-01-01

    This report introduces and provides an overview of assurance cases including theory, practice, and evaluation. This report includes a section that introduces the principles, terminology, and history of assurance cases. The core of the report presents twelve example uses of assurance cases from a range of domains, using a novel classification scheme. The report also reviews the state of the art in assurance case evaluation methods.

  19. Power transformers quality assurance

    CERN Document Server

    Dasgupta, Indrajit

    2009-01-01

    About the Book: With the view to attain higher reliability in power system operation, the quality assurance in the field of distribution and power transformers has claimed growing attention. Besides new developments in the material technology and manufacturing processes of transformers, regular diagnostic testing and maintenance of any engineering product may be ascertained by ensuring: right selection of materials and components and their quality checks. application of correct manufacturing processes any systems engineering. the user`s awareness towards preventive maintenance. The

  20. Home hemodialysis: a comprehensive review of patient-centered and economic considerations

    Science.gov (United States)

    Walker, Rachael C; Howard, Kirsten; Morton, Rachael L

    2017-01-01

    Internationally, the number of patients requiring treatment for end-stage kidney disease (ESKD) continues to increase, placing substantial burden on health systems and patients. Home hemodialysis (HD) has fluctuated in its popularity, and the rates of home HD vary considerably between and within countries although there is evidence suggesting a number of clinical, survival, economic, and quality of life (QoL) advantages associated with this treatment. International guidelines encourage shared decision making between patients and clinicians for the type of dialysis, with an emphasis on a treatment that aligned to the patients’ lifestyle. This is a comprehensive literature review of patient-centered and economic impacts of home HD with the studies published between January 2000 and July 2016. Data from the primary studies representing both efficiency and equity of home HD were presented as a narrative synthesis under the following topics: advantages to patients, barriers to patients, economic factors influencing patients, cost-effectiveness of home HD, and inequities in home HD delivery. There were a number of advantages for patients on home HD including improved survival and QoL and flexibility and potential for employment, compared to hospital HD. Similarly, there were several barriers to patients preferring or maintaining home HD, and the strategies to overcome these barriers were frequently reported. Good evidence reported that indigenous, low-income, and other socially disadvantaged individuals had reduced access to home HD compared to other forms of dialysis and that this situation compounds already-poor health outcomes on renal replacement therapy. Government policies that minimize barriers to home HD include reimbursement for dialysis-related out-of-pocket costs and employment-retention interventions for home HD patients and their family members. This review argues that home HD is a cost-effective treatment, and increasing the proportion of patients on this

  1. Orbital floor fractures: a retrospective review of 45 cases at a tertiary health care center.

    Science.gov (United States)

    Rhim, Chun H; Scholz, Thomas; Salibian, Ara; Evans, Gregory R D

    2010-03-01

    The purpose of this retrospective study was to investigate treatment options for orbital floor fractures at a Level 1 Trauma Center in Southern California. A review of 45 cases of isolated orbital floor fractures treated at the University of California at Irvine between February 2004 and April 2007 was done. Patients were retrospectively analyzed for gender, age, mechanism of injury, associated facial injuries, presenting symptoms, method of treatment, and postoperative complications. Thirty-six male patients and nine female patients were treated. Motor vehicle collision (26/45) was the most common cause of injury, and the mean age of the patients was 35.5 years (range: 15-81 years). Ecchymosis surrounding the orbital tissue was the most common presentation (38/45). Diplopia was present in 8 of 45 patients, with 1 patient requiring urgent decompression for retrobulbar hematoma. Forty-three patients underwent surgical repair; 40 underwent transconjunctival approach with lateral canthotomy; 17 underwent reconstruction with porous polyethylene Medpor (Porex Surgical, Inc., College Park, GA.); and 26 underwent reconstruction with a titanium mesh plate. Immediate postoperative complications included 12 patients with infraorbital numbness, 3 with diplopia, 1 with cellulitis, and 1 with ectropion with a subcilliary approach. Average timing of surgery of our study was 4.94 days (range, 1-20 days). Orbital floor fracture management has changed significantly over the past few decades with the introduction of new internal fixation methods and new materials for reconstructing orbital floor defects. Recommendations for surgical intervention on orbital floor fractures mostly depend on clinical examination and imaging studies. Consequences of inadequate repair of orbital floor fractures can lead to significant facial asymmetry and visual problems. Both porous polyethylene and titanium plates are effective tools for reconstructing the orbital floor. Our review demonstrates that

  2. Hyperhemolysis in Patients With Hemoglobinopathies: A Single-Center Experience and Review of the Literature.

    Science.gov (United States)

    Danaee, Anicee; Inusa, Baba; Howard, Jo; Robinson, Susan

    2015-10-01

    Hyperhemolysis is a severe and potentially life-threatening complication of transfusion described in numerous case reports and gaining recognition since 2009 via the UK Serious Hazards of Transfusion scheme. Although it is predominantly seen in patients with sickle cell disease, there are several reports of this complication in patients with other hemoglobinopathies as well as patients with a range of other hematologic diagnoses who have blood transfusions as part of their management. Our understanding of the underlying pathophysiology of this subtype of delayed transfusion reaction has increased over the last few years; however, there are still questions, which remain unanswered. In our center alone, we have encountered 9 cases in the last 5 years both in the adult and pediatric population. Here we discuss our experience in the diagnosis and management of this complication, and review other cases reported in the literature and the various existing theories behind the pathophysiology of this process. We also discuss the role of genotyping and using DNA technology to aid selection of the most appropriate blood for this patient group. With an increased awareness of hyperhemolysis, it would be advantageous to finally develop international registries to determine the true incidence of hyperhemolysis, better understand the pathophysiology, identify markers to predict which patients are at risk, and inform management guidelines.

  3. Cancer survivorship research: a review of the literature and summary of current NCI-designated cancer center projects.

    Science.gov (United States)

    Harrop, J Phil; Dean, Julie A; Paskett, Electra D

    2011-10-01

    The number of cancer survivors and the amount of cancer survivorship research have grown substantially during the past three decades. This article provides a review of interventional and observational cancer survivorship research efforts as well as a summary of current cancer survivorship research projects being conducted by National Cancer Institute-designated cancer centers in an effort to identify areas that need further attention.

  4. Quality Assurance of Quality Assurance Agencies from an Asian Perspective: Regulation, Autonomy and Accountability

    Science.gov (United States)

    Hou, Angela Yung-Chi; Ince, Martin; Tsai, Sandy; Chiang, Chung Lin

    2015-01-01

    As quality guardians of higher education, quality assurance agencies are required to guarantee the credibility of the review process and to ensure the objectivity and transparency of their decisions and recommendations. These agencies are therefore expected to use a range of internal and external approaches to prove the quality of their review…

  5. 76 FR 24894 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-03

    ... Biology Integrated Review Group; Cellular Mechanisms in Aging and Development Study Section. Date: June 13....hhs.gov . Name of Committee: Oncology 1--Basic Translational Integrated Review Group; Molecular... Committee: Integrative, Functional and Cognitive Neuroscience Integrated Review Group; Neurobiology...

  6. 77 FR 27073 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-08

    ... of Committee: Immunology Integrated Review Group; Immunity and Host Defense Study Section. Date: June... . Name of Committee: Immunology Integrated Review Group; Transplantation, Tolerance, and Tumor Immunology... . Name of Committee: Oncology 2--Translational Clinical Integrated Review Group; Cancer Biomarkers...

  7. 76 FR 60058 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-28

    ... Scientific Review Special Emphasis Panel, Cancer Etiology Overflow. Date: October 28, 2011. Time: 8 a.m. to 5... Review Special Emphasis Panel, Review of Immunology AREA Grant Applications. Date: October 28, 2011....

  8. 75 FR 52764 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-27

    ... for Scientific Review Special Emphasis Panel, Small Business: Neuroscience Education. Date: October 6... Cognitive Neuroscience Integrated Review Group, Neurobiology of Motivated Behavior Study Section. Date....gov . Name of Committee: Integrative, Functional and Cognitive Neuroscience Integrated Review...

  9. 78 FR 56904 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-16

    ... Integrated Review Group; Molecular and Cellular Hematology Study Section. Date: October 15-16, 2013. Time: 8...: Integrative, Functional and Cognitive Neuroscience Integrated Review Group; Neurobiology of Motivated...

  10. 78 FR 78985 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-12-27

    ... for Scientific Review Special Emphasis Panel Member Conflict: Genetics and Genomics. Date: January 24... Committee: Genes, Genomes, and Genetics Integrated Review Group Molecular Genetics B Study Section....

  11. 77 FR 59198 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-26

    ... Scientific Review Special Emphasis Panel; Small Business: Innovative Neuroscience K-12 Education. Date... Committee: Brain Disorders and Clinical Neuroscience Integrated Review Group; Acute Neural Injury...

  12. 76 FR 55400 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-07

    ... Genetics Integrated Review Group; Therapeutic Approaches to Genetic Diseases. Date: October 6, 2011. Time....gov . Name of Committee: Immunology Integrated Review Group; Vaccines Against Microbial Diseases...

  13. Home hemodialysis: a comprehensive review of patient-centered and economic considerations

    Directory of Open Access Journals (Sweden)

    Walker RC

    2017-02-01

    Full Text Available Rachael C Walker,1,2 Kirsten Howard,1 Rachael L Morton3 1School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia; 2Hawke’s Bay District Health Board, Hastings, New Zealand; 3NHMRC Clinical Trials Centre, Sydney Medical School, University of Sydney, Sydney, Australia Abstract: Internationally, the number of patients requiring treatment for end-stage kidney disease (ESKD continues to increase, placing substantial burden on health systems and patients. Home hemodialysis (HD has fluctuated in its popularity, and the rates of home HD vary considerably between and within countries although there is evidence suggesting a number of clinical, survival, economic, and quality of life (QoL advantages associated with this treatment. International guidelines encourage shared decision making between patients and clinicians for the type of dialysis, with an emphasis on a treatment that aligned to the patients’ lifestyle. This is a comprehensive literature review of patient-centered and economic impacts of home HD with the studies published between January 2000 and July 2016. Data from the primary studies representing both efficiency and equity of home HD were presented as a narrative synthesis under the following topics: advantages to patients, barriers to patients, economic factors influencing patients, cost-effectiveness of home HD, and inequities in home HD delivery. There were a number of advantages for patients on home HD including improved survival and QoL and flexibility and potential for employment, compared to hospital HD. Similarly, there were several barriers to patients preferring or maintaining home HD, and the strategies to overcome these barriers were frequently reported. Good evidence reported that indigenous, low-income, and other socially disadvantaged individuals had reduced access to home HD compared to other forms of dialysis and that this situation compounds already-poor health outcomes on renal

  14. Evolving Principles of Office Quality Assurance

    OpenAIRE

    Norman, Lee A.

    1988-01-01

    The application of medical quality assurance principles to ambulatory patient care using the traditional methods of medical chart audit, process review, and physician education has yielded generally disappointing results in improving patient care and physician performance. Newer methods assist physicians by providing patient and medical reference data at the time of a patient's visit. Techniques for tracking treatment outcomes and patients' test results and for providing instructions to patie...

  15. Review of fatigue and fracture research at NASA Langley Research Center

    Science.gov (United States)

    Everett, Richard A., Jr.

    1988-01-01

    Most dynamic components in helicopters are designed with a safe-life constant-amplitude testing approach that has not changed in many years. In contrast, the fatigue methodology in other industries has advanced significantly in the last two decades. Recent research at the NASA Langley Research Center and the U.S. Army Aerostructures Directorate at Langley are reviewed relative to fatigue and fracture design methodology for metallic components. Most of the Langley research was directed towards the damage tolerance design approach, but some work was done that is applicable to the safe-life approach. In the areas of testing, damage tolerance concepts are concentrating on the small-crack effect in crack growth and measurement of crack opening stresses. Tests were conducted to determine the effects of a machining scratch on the fatigue life of a high strength steel. In the area of analysis, work was concentrated on developing a crack closure model that will predict fatigue life under spectrum loading for several different metal alloys including a high strength steel that is often used in the dynamic components of helicopters. Work is also continuing in developing a three-dimensional, finite-element stress analysis for cracked and uncracked isotropic and anisotropic structures. A numerical technique for solving simultaneous equations called the multigrid method is being pursued to enhance the solution schemes in both the finite-element analysis and the boundary element analysis. Finally, a fracture mechanics project involving an elastic-plastic finite element analysis of J-resistance curve is also being pursued.

  16. Congenital bronchopulmonary malformations: A single-center experience and a review of literature

    Directory of Open Access Journals (Sweden)

    Kumar Basant

    2008-01-01

    Full Text Available Purpose: To present a single-center experience with 25 cases of bronchopulmonary malformations and the review the literature. Materials and Methods: We conducted a retrospective analysis of the medical records of patients with congenital bronchopulmonary malformations who were operated between July 1997 and July 2007 in our institute; we examined the modes of presentations, management, and outcome. Outcome of all patients was assessed over a short follow-up period (average 1.8 months. Results: Out of 25 patients, 18 (72% were male and 7 (28% were female. Age of patients ranged from 1 day to 11 years. The histopathological diagnosis was congenital cystic adenomatoid malformations [CCAM; n = 14 (56%], congenital lobar emphysema [CLE; n = 5 (20%], pulmonary sequestrations [PS; n = 3 (12%], and bronchogenic cysts [BC; n = 3 (12%]. Antenatal diagnosis was available in only 2 (8% patients. The common presenting symptoms were respiratory distress and chest infections. Lobectomy was the procedure of choice . Mortality was 16% (n = 4; M: F = 3: 1. Two patients died because of overwhelming sepsis, one from compromised cardiac function, and one from aspiration which might possibly have been prevented. Conclusion: Patients with progressive respiratory distress due to these anomalies may require urgent surgical intervention regardless of age. The surgical outcome is favorable, with manageable complications. Plain x-ray chest and CT of thorax are usually sufficient for diagnosis and planning of treatment. Pathological diagnosis may differ from the imaging diagnosis. Mortality is found to be more in neonates. Apart from initial stabilization, resection of lesion and careful postoperative care is necessary to reduce mortality and morbidity.

  17. Peripherally inserted central venous catheter safety in burn care: a single-center retrospective cohort review.

    Science.gov (United States)

    Austin, Ryan E; Shahrokhi, Shahriar; Bolourani, Siavash; Jeschke, Marc G

    2015-01-01

    The use of peripherally inserted central catheter (PICC) line for central venous access in thermally injured patients has increased in recent years despite a lack of evidence regarding safety in this patient population. A recent survey of invasive catheter practices among 44 burn centers in the United States found that 37% of burn units use PICC lines as part of their treatment protocol. The goal of this study was to compare PICC-associated complication rates with the existing literature in both the critical care and burn settings. The methodology involved is a single institution retrospective cohort review of patients who received a PICC line during admission to a regional burn unit between 2008 and 2013. Fifty-three patients were identified with a total of seventy-three PICC lines. The primary outcome measurement for this study was indication for PICC line discontinuation. The most common reason for PICC line discontinuation was that the line was no longer indicated (45.2%). Four cases of symptomatic upper extremity deep vein thrombosis (5.5%) and three cases of central line-associated bloodstream infection (4.3%, 2.72 infections per 1000 line days) were identified. PICC lines were in situ an average of 15 days (range 1 to 49 days). We suggest that PICC line-associated complication rates are similar to those published in the critical care literature. Though these rates are higher than those published in the burn literature, they are similar to central venous catheter-associated complication rates. While PICC lines can be a useful resource in the treatment of the thermally injured patient, they are associated with significant and potentially fatal risks.

  18. Critical care issues in solid organ injury: Review and experience in a tertiary trauma center

    Directory of Open Access Journals (Sweden)

    Chhavi Sawhney

    2014-01-01

    Full Text Available Background and Aim: Solid organ (spleen and liver injuries are dreaded by both surgeons and anesthesiologists because of associated high morbidity and mortality. The purpose of this review is to describe our experience of critical care concerns in solid organ injury, which otherwise has been poorly addressed in the literature. Materials and Methods: Retrospective cohort of solid organ injury (spleen and liver patients was done from January 2010 to December 2011 in tertiary level trauma Center. Results: Out of 624 abdominal trauma patients, a total of 212 patients (70% were admitted in intensive care unit (ICU. Their ages ranged from 6 to 74 years (median 24 years. Nearly 89% patients in liver trauma and 84% patients in splenic trauma were male. Mechanism of injury was blunt abdominal trauma in 96% patients and the most common associated injury was chest trauma. Average injury severity score, sequential organ failure assessment, lactate on admission was 16.84, 4.34 and 3.42 mmol/L and that of dying patient were 29.70, 7.73 and 5.09 mmol/L, respectively. Overall mortality of ICU admitted solid organ injury was 15.55%. Major issues of concern in splenic injury were hemorrhagic shock, overwhelming post-splenectomy infection and post-splenectomy vaccination. Issues raised in liver injury are damage control surgery, deadly triad, thromboelastography guided transfusion protocols and hemostatic agents. Conclusions: A protocol-based and multidisciplinary approach in high dependency unit can significantly reduce morbidity and mortality in patients with solid organ injury.

  19. Critical care issues in solid organ injury: Review and experience in a tertiary trauma center

    Science.gov (United States)

    Sawhney, Chhavi; Kaur, Manpreet; Gupta, Babita; Singh, P. M.; Gupta, Amit; Kumar, Subodh; Misra, M. C.

    2014-01-01

    Background and Aim: Solid organ (spleen and liver) injuries are dreaded by both surgeons and anesthesiologists because of associated high morbidity and mortality. The purpose of this review is to describe our experience of critical care concerns in solid organ injury, which otherwise has been poorly addressed in the literature. Materials and Methods: Retrospective cohort of solid organ injury (spleen and liver) patients was done from January 2010 to December 2011 in tertiary level trauma Center. Results: Out of 624 abdominal trauma patients, a total of 212 patients (70%) were admitted in intensive care unit (ICU). Their ages ranged from 6 to 74 years (median 24 years). Nearly 89% patients in liver trauma and 84% patients in splenic trauma were male. Mechanism of injury was blunt abdominal trauma in 96% patients and the most common associated injury was chest trauma. Average injury severity score, sequential organ failure assessment, lactate on admission was 16.84, 4.34 and 3.42 mmol/L and that of dying patient were 29.70, 7.73 and 5.09 mmol/L, respectively. Overall mortality of ICU admitted solid organ injury was 15.55%. Major issues of concern in splenic injury were hemorrhagic shock, overwhelming post-splenectomy infection and post-splenectomy vaccination. Issues raised in liver injury are damage control surgery, deadly triad, thromboelastography guided transfusion protocols and hemostatic agents. Conclusions: A protocol-based and multidisciplinary approach in high dependency unit can significantly reduce morbidity and mortality in patients with solid organ injury. PMID:25538517

  20. Effectiveness of person-centered care on people with dementia: a systematic review and meta-analysis

    Science.gov (United States)

    Kim, Sun Kyung; Park, Myonghwa

    2017-01-01

    Background Person-centered care is a holistic and integrative approach designed to maintain well-being and quality of life for people with dementia, and it includes the elements of care, the individual, the carers, and the family. Aim A systematic literature review and meta-analysis were undertaken to investigate the effectiveness of person-centered care for people with dementia. Methods Literature searches were undertaken using six databases including Medline, EMBASE, CINAHL, PsycINFO, Cochrane Database, and KoreaMed using the following keywords: cognition disorder, dementia, person-centered care, patient-centered care, client-centered care, relationship-centered care, and dementia care. The searches were limited to interventional studies written in English and Korean and included randomized controlled studies and noncontrolled studies for people with dementia living in any setting. Results Nineteen interventional studies, including 3,985 participants, were identified. Of these, 17 studies were from long-term care facilities and two studies were from homecare settings. The pooled data from randomized controlled studies favored person-centered care in reducing agitation, neuropsychiatric symptoms, and depression and improving the quality of life. Subgroup analysis identified greater effectiveness of person-centered care when implemented for people with less severe dementia. For agitation, short-term interventions had a greater effect (standardized mean difference [SMD]: −0.434; 95% conference interval [CI]: −0.701 to −0.166) than long-term interventions (SMD: −0.098; 95% CI: −0.190 to 0.007). Individualized activities resulted in a significantly greater beneficial effect than standard care (SMD: 0.513; 95% CI: −0.994 to −0.032). However, long-term, staff education, and cultural change interventions had a greater effect on improving the quality of life for people with dementia (SMD: 0.191; 95% CI: 0.079 to 0.302). Conclusion This systematic review and

  1. 76 FR 55076 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2011-09-06

    ...: Hyatt Regency Bethesda, One Bethesda Metro Center, Bethesda, MD 20814. Contact Person: Patricia Greenwel... and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street, NW., Washington, DC...

  2. 77 FR 58852 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-24

    ... evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street NW., Washington, DC 20036. Contact... and evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center,...

  3. Improving the Quality of Services in Residential Treatment Facilities: A Strength-Based Consultative Review Process

    Science.gov (United States)

    Pavkov, Thomas W.; Lourie, Ira S.; Hug, Richard W.; Negash, Sesen

    2010-01-01

    This descriptive case study reports on the positive impact of a consultative review methodology used to conduct quality assurance reviews as part of the Residential Treatment Center Evaluation Project. The study details improvement in the quality of services provided to youth in unmonitored residential treatment facilities. Improvements were…

  4. 76 FR 11498 - Submission for OMB Review; Comment Request; Generic Submission of Technology Transfer Center (TTC...

    Science.gov (United States)

    2011-03-02

    ... process improvements for services provided by the NCI TTC to the research community. The results will be... Submission of Technology Transfer Center (TTC) External Customer Satisfaction Surveys (NCI) SUMMARY: Under... control number. Proposed Collection: Title: Generic Submission of Technology Transfer Center...

  5. Assessing Community Informatics: A Review of Methodological Approaches for Evaluating Community Networks and Community Technology Centers.

    Science.gov (United States)

    O'Neil, Dara

    2002-01-01

    Analyzes the emerging community informatics evaluation literature to develop an understanding of the indicators used to gauge project impacts in community networks and community technology centers. The study finds that community networks and community technology center assessments fall into five key areas: strong democracy; social capital;…

  6. 77 FR 56855 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-14

    ... grant applications. Place: St. Gregory Hotel, 2033 M Street NW., Washington, DC 20036. Contact Person... evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin... Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. Contact Person:...

  7. How Are We Doing? A Review of Assessments within Writing Centers

    Science.gov (United States)

    Gofine, Miriam

    2012-01-01

    Today, nearly forty years after writing centers first began to proliferate, it is worthwhile to reflect on the themes that emerge from empirical material surrounding writing center assessments, for reflecting on these themes may help administrators to refine current assessment practices and scholars to redirect their research. The goal of this…

  8. Effectiveness of person-centered care on people with dementia: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Kim SK

    2017-02-01

    Full Text Available Sun Kyung Kim, Myonghwa Park Education and Research Center for Evidence Based Nursing Knowledge, College of Nursing, Chungnam National University, Daejeon, Republic of Korea Background: Person-centered care is a holistic and integrative approach designed to maintain well-being and quality of life for people with dementia, and it includes the elements of care, the individual, the carers, and the family.Aim: A systematic literature review and meta-analysis were undertaken to investigate the effectiveness of person-centered care for people with dementia.Methods: Literature searches were undertaken using six databases including Medline, EMBASE, CINAHL, PsycINFO, Cochrane Database, and KoreaMed using the following keywords: cognition disorder, dementia, person-centered care, patient-centered care, client-centered care, relationship-centered care, and dementia care. The searches were limited to interventional studies written in English and Korean and included randomized controlled studies and noncontrolled studies for people with dementia living in any setting.Results: Nineteen interventional studies, including 3,985 participants, were identified. Of these, 17 studies were from long-term care facilities and two studies were from homecare settings. The pooled data from randomized controlled studies favored person-centered care in reducing agitation, neuropsychiatric symptoms, and depression and improving the quality of life. Subgroup analysis identified greater effectiveness of person-centered care when implemented for people with less severe dementia. For agitation, short-term interventions had a greater effect (standardized mean difference [SMD]: -0.434; 95% conference interval [CI]: -0.701 to -0.166 than long-term interventions (SMD: -0.098; 95% CI: -0.190 to 0.007. Individualized activities resulted in a significantly greater beneficial effect than standard care (SMD: 0.513; 95% CI: -0.994 to -0.032. However, long-term, staff education, and

  9. The case of sustainability assurance: constructing a new assurance service

    NARCIS (Netherlands)

    O'Dwyer, B.

    2011-01-01

    This paper presents an in-depth longitudinal case study examining the processes through which practitioners in two Big 4 professional services firms have attempted to construct sustainability assurance (independent assurance on sustainability reports). Power’s (1996, 1997, 1999, 2003) theorization o

  10. Quality Assurance in the Endoscopy Suite: Sedation and Monitoring.

    Science.gov (United States)

    Harris, Zachary P; Liu, Julia; Saltzman, John R

    2016-07-01

    Recent development and expansion of endoscopy units has necessitated similar progress in the quality assurance of procedure sedation and monitoring. The large number of endoscopic procedures performed annually underlies the need for standardized quality initiatives focused on mitigating patient risk before, during, and immediately after endoscopic sedation, as well as improving procedure outcomes and patient satisfaction. Specific standards are needed for newer sedation modalities, including propofol administration. This article reviews the current guidelines and literature concerning quality assurance and endoscopic procedure sedation.

  11. Radiotherapy Quality Assurance Report From Children's Oncology Group AHOD0031

    Energy Technology Data Exchange (ETDEWEB)

    Dharmarajan, Kavita V. [Mount Sinai Medical Center, New York, New York (United States); Friedman, Debra L. [Vanderbilt University, Nashville, Tennessee (United States); FitzGerald, T.J. [Quality Assurance Review Center, Lincoln, Rhode Island (United States); McCarten, Kathleen M. [Rhode Island Hospital/Warren Alpert Medical School of Brown University, Providence, Rhode Island (United States); Constine, Louis S. [University of Rochester Medical Center, Rochester, New York (United States); Chen, Lu [Children' s Oncology Group, Arcadia, California (United States); Kessel, Sandy K.; Iandoli, Matt; Laurie, Fran [Quality Assurance Review Center, Lincoln, Rhode Island (United States); Schwartz, Cindy L. [MD Anderson Cancer Center, Houston, Texas (United States); Wolden, Suzanne L., E-mail: woldens@mskcc.org [Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

    2015-04-01

    Purpose: A phase 3 trial assessing response-based therapy in intermediate-risk Hodgkin lymphoma mandated real-time central review of involved field radiation therapy (IFRT) and imaging records by a centralized review center to maximize protocol compliance. We report the impact of centralized radiation therapy review on protocol compliance. Methods and Materials: Review of simulation films, port films, and dosimetry records was required before and after treatment. Records were reviewed by study-affiliated or review center–affiliated radiation oncologists. A deviation of 6% to 10% from protocol-specified dose was scored as “minor”; a deviation of >10% was “major.” A volume deviation was scored as “minor” if margins were less than specified or “major” if fields transected disease-bearing areas. Interventional review and final compliance review scores were assigned to each radiation therapy case and compared. Results: Of 1712 patients enrolled, 1173 underwent IFRT at 256 institutions in 7 countries. An interventional review was performed in 88% of patients and a final review in 98%. Overall, minor and major deviations were found in 12% and 6% of patients, respectively. Among the cases for which ≥1 pre-IFRT modification was requested by the Quality Assurance Review Center and subsequently made by the treating institution, 100% were made compliant on final review. By contrast, among the cases for which ≥1 modification was requested but not made by the treating institution, 10% were deemed compliant on final review. Conclusions: In a large trial with complex treatment pathways and heterogeneous radiation therapy fields, central review was performed in a large percentage of cases before IFRT and identified frequent potential deviations in a timely manner. When suggested modifications were performed by the institutions, deviations were almost eliminated.

  12. 78 FR 32670 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-31

    ...- 9918, niw@csr.nih.gov . Name of Committee: Genes, Genomes, and Genetics Integrated Review Group... Diabetes Clinical Research. Date: June 27, 2013. Time: 3:30 p.m. to 5:00 p.m. Agenda: To review...

  13. 75 FR 51082 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-18

    ...: Technology Development for High-Throughput Structural Biology Research Review. Date: September 14-15, 2010...: Biology of Development and Aging Integrated Review Group; Development--1 Study Section. Date: September...

  14. 77 FR 6811 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-09

    ... for Scientific Review Special Emphasis Panel; Small Business: Non-HIV Microbial Vaccine Development... development and resistance. Date: February 28, 2012. Time: 3 p.m. to 5 p.m. Agenda: To review and...

  15. 78 FR 5468 - Center for Scientific Review; Notice of Closed Meetings

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    2013-01-25

    ... Scientific Review Special Emphasis Panel; PAR10-169: Academic Industrial Partnership (2013/05). Date... Instrumentation. Date: February 22, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate...

  16. 76 FR 2399 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-13

    .... garofalors@csr.nih.gov . Name of Committee: Molecular, Cellular and Developmental Neuroscience Integrated...: Molecular, Cellular and Developmental Neuroscience Integrated Review Group, Cellular and Molecular Biology...: Healthcare Delivery and Methodologies Integrated Review Group, Biostatistical Methods and Research......

  17. 78 FR 3904 - Center for Scientific Review; Notice of Closed Meetings

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    2013-01-17

    ..., yakovleva@csr.nih.gov . Name of Committee: Molecular, Cellular and Developmental Neuroscience Integrated...: Molecular, Cellular and Developmental Neuroscience Integrated Review Group; Drug Discovery for the Nervous...: Healthcare Delivery and Methodologies Integrated Review Group; Biostatistical Methods and Research...

  18. 77 FR 2739 - Center for Scientific Review; Notice of Closed Meetings

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    2012-01-19

    ...: Biobehavioral and Behavioral Processes Integrated Review Group; Language and Communication Study Section. Date... Genetics Integrated Review Group; Molecular Genetics A Study Section. Date: February 13-14, 2012. Time: 8...

  19. 76 FR 55691 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-08

    ...: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Clinical and Integrative... Review Group, Social Psychology, Personality and Interpersonal Processes Study Section. Date: October 6-7... Panel, Social Psychology, Personality and Interpersonal Processes. Date: October 6, 2011. Time: 3...

  20. 75 FR 56554 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-16

    ... Conflict: Cardiac Ion Channels. Date: September 29, 2010. Time: 2 p.m. to 4 p.m. Agenda: To review and... Review Special Emphasis Panel; Mental Health and Developmental Disorders. Date: October 1, 2010. Time:...

  1. 77 FR 29672 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-18

    .... Agenda: To review and evaluate grant applications. Place: Marina del Rey Hotel, 13534 Bali Way, Marina... Review Group; Tumor Cell Biology Study Section. Date: June 14-15, 2012. Time: 8:00 a.m. to 5:00 p.m...--Translational Clinical Integrated Review Group; Radiation Therapeutics and Biology Study Section. Date: June...

  2. 76 FR 24897 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-03

    ... Cell and Molecular Biology Study Section. Date: June 9, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review....m. Agenda: To review and evaluate grant applications. Place: Marina del Rey Marriott, 4100 Admiralty Way, Marina del Rey, CA 90292. Contact Person: Olga A Tjurmina, PhD, Scientific Review Officer,...

  3. 78 FR 3905 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-17

    ... Review Special Emphasis Panel; Member Conflict: Basic Biology of Neurological Disorders. Date: February.... to 6:30 p.m. Agenda: To review and evaluate grant applications. Place: Marina Del Rey Hotel, 13534 Bali Way, Marina Del Rey, CA 90292. Contact Person: Yuanna Cheng, MD, Ph.D., Scientific Review...

  4. 77 FR 8888 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-15

    ... 5 p.m. Agenda: To review and evaluate grant applications. Place: Ritz-Carlton Marina del Rey, 4375 Admiralty Way, Marina del Rey, CA 90292. Contact Person: Mark Lindner, Ph.D., Scientific Review Officer... for Scientific Review Special Emphasis Panel; Member Conflict: Cell Biology. Date: March 6, 2012....

  5. 77 FR 14028 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-03-08

    ...-1323, assamunu@csr.nih.gov . Name of Committee: Biology of Development and Aging Integrated Review....m. Agenda: To review and evaluate grant applications. Place: Marina del Rey Marriott, 4100 Admiralty Way, Marina del Rey, CA 90292. Contact Person: Hilary D. Sigmon, Ph.D., Scientific Review...

  6. 75 FR 54156 - Center for Scientific Review; Notice of Closed Meetings

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    2010-09-03

    ...: 8 a.m. to 5 p.m. Agenda: To review and evaluate grant applications. Place: Marina del Rey Hotel, 13534 Bali Way, Marina del Rey, CA 90292. Contact Person: Lambratu Rahman, PhD, Scientific Review... of Committee: Cell Biology Integrated Review Group, Biology and Diseases of the Posterior Eye...

  7. 77 FR 293 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-04

    ... Bioengineering Integrated Review Group; Surgery, Anesthesiology and Trauma Study Section. Date: February 1-2...: Immunology Integrated Review Group; Immunity and Host Defense Study Section. Date: February 2-3, 2012. Time... Committee: Immunology Integrated Review Group; Cellular and Molecular Immunology--B Study Section....

  8. 75 FR 25275 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-07

    ...@nih.gov . Name of Committee: Genes, Genomes, and Genetics Integrated Review Group; Genomics...-435- 1033, hoshawb@csr.nih.gov Name of Committee: Genes, Genomes, and Genetics Integrated Review Group; Molecular Genetics B Study Section. Date: June 1-2, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review...

  9. 78 FR 26644 - Center for Scientific Review; Notice of Closed Meetings

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    2013-05-07

    ... Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review Group Synthetic and Biological Chemistry B Study Section Date: June 4-5, 2013. Time: 8:30 a.m. to 5:00 p.m. Agenda: To review and... . Name of Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review...

  10. 76 FR 26736 - Center for Scientific Review; Notice of Closed Meetings

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    2011-05-09

    ... Respiratory Sciences Integrated Review Group, Clinical and Integrative Cardiovascular Sciences Study Section... and Microbiology Integrated Review Group, Virology--B Study Section. Date: June 16-17, 2011. Time: 8... Diseases and Microbiology Integrated Review Group, Virology--A Study Section. Date: June 16-17, 2011....

  11. 75 FR 25273 - Center for Scientific Review; Notice of Closed Meetings

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    2010-05-07

    ... Integrated Review Group, Cancer Molecular Pathobiology Study Section. Date: June 3-4, 2010. Time: 8 a.m. to 5... 20892, 301-435-1254, yakovleva@csr.nih.gov . Name of Committee: Immunology Integrated Review Group...- 2037, mackj2@csr.nih.gov . Name of Committee: Immunology Integrated Review Group, Immunity and...

  12. 75 FR 27794 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-18

    ...@csr.nih.gov . Name of Committee: Immunology Integrated Review Group; Transplantation, Tolerance, and Tumor Immunology Study Section. Date: June 10-11, 2010. Time: 8 a.m. to 4 p.m. Agenda: To review and...: Oncology 2--Translational Clinical Integrated Review Group; Cancer Immunopathology and Immunotherapy...

  13. 75 FR 53317 - Center for Scientific Review; Notice of Closed Meetings

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    2010-08-31

    ..., Cancer Etiology Study Section. Date: October 7-8, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review and.... riverase@csr.nih.gov . Name of Committee: Oncology 1--Basic Translational Integrated Review Group, Cancer.... (301) 408- 9882. durrantv@csr.nih.gov . Name of Committee: Immunology Integrated Review Group,...

  14. 77 FR 3277 - Center for Scientific Review; Notice of Closed Meetings

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    2012-01-23

    ... Low-Cost Medical Devices. Date: February 15-16, 2012. Time: 11 a.m. to 6 p.m. Agenda: To review and... for Scientific Review Special Emphasis Panel Clinical and Translational Imaging Applications. Date... Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee...

  15. 78 FR 1216 - Center for Scientific Review; Notice of Closed Meetings

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    2013-01-08

    ...: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Cellular Aspects of Diabetes and Obesity Study Section. Date: February 7, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review...: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Clinical and...

  16. 76 FR 3643 - Center for Scientific Review; Notice of Closed Meetings

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    2011-01-20

    ... Integrated Review Group, Vector Biology Study Section. Date: February 10, 2011. Time: 8 a.m. to 5 p.m. Agenda... Review Group, Tumor Cell Biology Study Section. Date: February 14-15, 2011. Time: 8 a.m. to 5 p.m. Agenda... for Scientific Review Special Emphasis Panel, Societal and Ethical Issues in Research. Date:...

  17. 76 FR 63315 - Center for Scientific Review; Notice of Closed Meetings

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    2011-10-12

    ... for Scientific Review Special Emphasis Panel, Drug Discovery for the Nervous System II. Date: November... Review Special Emphasis Panel, Translational Research in Diabetes, Obesity and Endocrinology. Date... Systems. Date: November 3-4, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate...

  18. 75 FR 994 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-07

    ...; Developmental Brain Disorders Study Section. Date: February 4-5, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review..., Genomes, and Genetics Integrated Review Group; Molecular Genetics C Study Section. Date: February 4-5...: Molecular, Cellular and Developmental Neuroscience Integrated Review Group; Neural Oxidative Metabolism...

  19. Review of the Lujan neutron scattering center: basic energy sciences prereport February 2009

    Energy Technology Data Exchange (ETDEWEB)

    Hurd, Alan J [Los Alamos National Laboratory; Rhyne, James J [Los Alamos National Laboratory; Lewis, Paul S [Los Alamos National Laboratory

    2009-01-01

    The Lujan Neutron Scattering Center (Lujan Center) at LANSCE is a designated National User Facility for neutron scattering and nuclear physics studies with pulsed beams of moderated neutrons (cold, thermal, and epithermal). As one of five experimental areas at the Los Alamos Neutron Science Center (LANSCE), the Lujan Center hosts engineers, scientists, and students from around the world. The Lujan Center consists of Experimental Room (ER) 1 (ERl) built by the Laboratory in 1977, ER2 built by the Office of Basic Energy Sciences (BES) in 1989, and the Office Building (622) also built by BES in 1989, along with a chem-bio lab, a shop, and other out-buildings. According to a 1996 Memorandum of Agreement (MOA) between the Defense Programs (DP) Office of the National Nuclear Security Agency (NNSA) and the Office of Science (SC, then the Office of Energy Research), the Lujan Center flight paths were transferred from DP to SC, including those in ERI. That MOA was updated in 2001. Under the MOA, NNSA-DP delivers neutron beam to the windows of the target crypt, outside of which BES becomes the 'landlord.' The leveraging nature of the Lujan Center on the LANSCE accelerator is a substantial annual leverage to the $11 M BES operating fund worth approximately $56 M operating cost of the linear accelerator (LINAC)-in beam delivery.

  20. 75 FR 33627 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-14

    ... applications. Place: St. Gregory Hotel, 2033 M Street, NW., Washington, DC 20036. Contact Person: Mark P Rubert...: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814....

  1. Recent Trends in Quality Assurance

    Science.gov (United States)

    Amaral, Alberto; Rosa, Maria Joao

    2010-01-01

    In this paper we present a brief description of the evolution of quality assurance in Europe, paying particular attention to its relationship to the rising loss of trust in higher education institutions. We finalise by analysing the role of the European Commission in the setting up of new quality assurance mechanisms that tend to promote…

  2. Center for risk research: A review of work 1988-1991

    Energy Technology Data Exchange (ETDEWEB)

    Sjoeberg, L.

    1992-01-01

    This report gives a summary of the research published during the first 4 years of the Center for Risk Research at the Stockholm School of Economics. Risk research carried out so far at the Center has been concerned with mapping of attitudes and risk perceptions with regard to nuclear risks, AIDS, military flight risks, and economic risks. There has also been some methodological work and some work on the relationship between risk perception and interests.

  3. [Quality assurance in occupational health services].

    Science.gov (United States)

    Michalak, J

    1996-01-01

    The general conditions influencing the quality assurance and audit in Polish occupational health services are presented. The factors promoting or hampering the implementation of quality assurance and audits are also discussed. The major influence on the transformation of Polish occupational health services in exorted by employers who are committed to cover the costs of the obligatory prophylactic examination of their employees. This is the factor which also contributes to the improvement of quality if services. The definitions of the most important terms are reviewed to highlight their accordance with the needs of occupational health services in Poland. The examples of audit are presented and the elements of selected methods of auditing are suggested to be adopted in Poland.

  4. 75 FR 80830 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-12-23

    ...-435- 1042, capraramg@mail.nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group; Pregnancy and Neonatology Study Section. Date: January...

  5. 77 FR 4050 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-26

    ... Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Pregnancy... 20892, (301) 435-4511, ronald.adkins@nih.gov . Name of Committee: Endocrinology, Metabolism,...

  6. 75 FR 57967 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-23

    .... Place: Courtyard by Marriot, 5520 Wisconsin Avenue, Chevy Chase, MD 20815. Contact Person: James P...: To review and evaluate grant applications. Place: Washington Marriott Wardman Park Hotel,...

  7. 78 FR 31954 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-28

    ... Microbiology Integrated Review Group; Drug Discovery and Mechanisms of Antimicrobial Resistance Study Section...: May 21, 2013. Melanie J. Gray, Program Analyst, Office of Federal Advisory Committee Policy....

  8. 77 FR 53205 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-08-31

    ... Health Behavior Integrated Review Group, Social Psychology, Personality and Interpersonal Processes Study...@csr.nih.gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine;...

  9. 75 FR 54893 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-09

    ... Drive, Bethesda, MD 20892. (Virtual Meeting.) Contact Person: John Bishop, PhD, Scientific Review... Hotel, 2430 Pennsylvania Avenue, NW., Washington, DC 20037. Contact Person: Michael K Schmidt,...

  10. 75 FR 26972 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-13

    ... Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group... Emphasis Panel, Collaborative: Risk Assessment for Autism Spectrum Disorders. Date: June 7, 2010. Time:...

  11. 75 FR 54159 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-03

    ... Review Group; Social Psychology, Personality and Interpersonal Processes Study Section. Date: October 11... of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical...

  12. Job Demand and Control Interventions: A Stakeholder-Centered Best-Evidence Synthesis of Systematic Reviews on Workplace Disability

    Directory of Open Access Journals (Sweden)

    K Williams-Whitt

    2015-03-01

    Full Text Available Background: Physical and psychological job demands in combination with the degree of control a worker has over task completion, play an important role in reducing stress. Occupational stress is an important, modifiable factor affecting work disability. However, the effectiveness of reducing job demands or increasing job control remains unclear, particularly for outcomes of interest to employers, such as absenteeism or productivity.Objective: This systematic review reports on job demand and control interventions that impact absenteeism, productivity and financial outcomes.Methods: A stakeholder-centered best-evidence synthesis was conducted with researcher and stakeholder collaboration throughout. Databases and grey literature were searched for systematic reviews between 2000 and 2012: Medline, EMBASE, the Cochrane Database of Systematic Reviews, DARE, CINAHL, PsycINFO, TRIP, health-evidence.ca, Rehab+, National Rehabilitation Information Center (NARIC, and Institute for Work and Health. Articles were assessed independently by two researchers for inclusion criteria and methodological quality. Differences were resolved through consensus.Results: The search resulted in 3363 unique titles. After review of abstracts, 115 articles were retained for full-text review. 11 articles finally met the inclusion criteria and are summarized in this synthesis. The best level of evidence we found indicates that multimodal job demand reductions for either at-work or off-work workers will reduce disability-related absenteeism.Conclusion: In general, the impacts of interventions that aim to reduce job demands or increase job control can be positive for the organization in terms of reducing absenteeism, increasing productivity and cost-effectiveness. However, more high quality research is needed to further assess the relationships and quantify effect sizes for the interventions and outcomes reviewed in this study.

  13. 75 FR 28623 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-21

    ...: Pregnancy and Reproduction. Date: June 14-15, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate... Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Integrative Nutrition and Metabolic Processes Study Section. Date: June 14, 2010. Time: 8 a.m. to 6...

  14. 78 FR 9064 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-07

    ... for Scientific Review Special Emphasis Panel; Member Conflict: Autoimmune and Infectious Diseases...: Biological Chemistry, Biophysics, and Drug Discovery. Date: March 4, 2013. Time: 8:30 a.m. to 6:00 p.m... for Scientific Review Special Emphasis Panel; PAR Panel: Lymphatics in Health and Disease in...

  15. 77 FR 26300 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-03

    ...-435-1169, greenwep@csr.nih.gov . ] This notice is being published less than 15 days prior to the... Research, and Recovery. Date: June 1, 2012. Time: 5:00 p.m. to 6:00 p.m. Agenda: To review and evaluate..., brontetinkewjm@csr.nih.gov . Name of Committee: Cardiovascular and Respiratory Sciences Integrated Review...

  16. 76 FR 65203 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-10-20

    ...@csr.nih.gov . Name of Committee: AIDS and Related Research Integrated Review Group, AIDS Molecular and..., roebuckk@csr.nih.gov . Name of Committee: AIDS and Related Research Integrated Review Group, AIDS..., Room 5218, MSC 7852, Bethesda, MD 20892, 301-435- 1775, rubertm@csr.nih.gov . Name of Committee:...

  17. 75 FR 6676 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-10

    ... Business: Genes, Genomes, and Genetics. Date: March 4, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and...: Diabetes, Obesity and Nutrition. Date: March 4-5, 2010. Time: 10 a.m. to 2 p.m. Agenda: To review...

  18. 78 FR 3009 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-15

    ... Developmental Biology AREA Review. Date: February 6-7, 2013. Time: 8:00 a.m. to 5:30 p.m. Agenda: To review and...: Systems Developmental Biology for Understanding Embryonic Development and the Ontogeny of Structural Birth...: Marina del Rey Hotel, 13534 Bali Way, Marina Del Rey, CA 90292. Contact Person: Kathryn Kalasinsky,...

  19. 78 FR 5466 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-25

    ... Integrated Review Group, Prokaryotic Cell and Molecular Biology Study Section. Date: February 21, 2013. Time... applications. Place: Marina del Rey Hotel, 13534 Bali Way, Marina del Rey, CA 90292. Contact Person: John C... 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Marina del Rey Hotel, 13534...

  20. 75 FR 64316 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-10-19

    ... Biology. Date: November 9-10, 2010. Time: 8 a.m. to 11 p.m. Agenda: To review and evaluate grant..., 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant applications. Place: Marina del Rey Marriott, 4100 Admiralty Way, Marina del Rey, CA 90292. Contact Person: Eduardo A Montalvo, PhD,...

  1. 78 FR 735 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-01-04

    ... Respiratory Sciences Integrated Review Group, Lung Cellular, Molecular, and Immunobiology Study Section. Date... Cognitive Neuroscience Integrated Review Group, Neurobiology of Motivated Behavior Study Section. Date..., Clinical Molecular Imaging and Probe Development. Date: February 6-7, 2013. Time: 7:00 p.m. to 2:00...

  2. 75 FR 54641 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-08

    ... Neuroscience Integrated Review Group; Neural Oxidative Metabolism and Death Study Section. Date: October 4-5...: Neural Control. Date: October 13-14, 2010. Time: 7 a.m. to 8 p.m. Agenda: To review and evaluate grant.... Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. BILLING CODE 4140-01-P...

  3. 75 FR 1064 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-08

    ... Committee: Genes, Genomes, and Genetics Integrated Review Group; Genomics, Computational Biology and... 20892, 301-435- 1033, hoshawb@csr.nih.gov . Name of Committee: Genes, Genomes, and Genetics Integrated Review Group; Molecular Genetics B Study Section. Date: February 3-4, 2010. Time: 7 p.m. to 6 p.m....

  4. 76 FR 54240 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-31

    ...: Brain Disorders and Clinical Neuroscience Integrated Review Group, Brain Injury and Neurovascular... Committee: Infectious Diseases and Microbiology Integrated Review Group, Virology--A Study Section. Date..., Pathophysiology and Clinical Studies of Osteonecrosis of the Jaw. Date: October 5, 2011. Time: 12 p.m. to 5...

  5. 77 FR 54583 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-05

    ... Disorders and Clinical Neuroscience Integrated Review Group, Aging Systems and Geriatrics Study Section... . Name of Committee: Infectious Diseases and Microbiology Integrated Review Group, Virology--B Study... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306,...

  6. 78 FR 57169 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-17

    ... Committee: Infectious Diseases and Microbiology Integrated Review Group; Virology--A Study Section. Date... Committee: Infectious Diseases and Microbiology Integrated Review Group; Clinical Research and Field Studies... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306,...

  7. 77 FR 31030 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-24

    ...: Biobehavioral and Behavioral Processes Integrated Review Group; Cognition and Perception Study Section. Date..., Cognition and Perception. Date: June 21-22, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and... Emphasis Panel; PAR Panel: Brain Disorders in the Developing World Research Across the Lifespan. Date:...

  8. 78 FR 35943 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-06-14

    ... Special Emphasis Panel; Small Business: Cancer Drug Developments & Therapeutics. Date: July 9-10, 2013... Adaptive Immunology. Date: July 9, 2013. Time: 11:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant... Integrated Review Group; AIDS Immunology and Pathogenesis Study Section. Date: July 11, 2013. Time: 8:00...

  9. 76 FR 6486 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-04

    ... Scientific Review Special Emphasis Panel; Neurodegeneration, Trauma, Immunology and Imaging. Date: March 7-8... Cancer Study Section. Date: March 8, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant... ] Conflicts: Lung Immunology, Asthma, and Cystic Fibrosis Applications. Date: March 9, 2011. Time: 9 a.m....

  10. 75 FR 1066 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-08

    ... Epidemiology Integrated Review Group; Epidemiology of Cancer Study Section. Date: February 4-5, 2010. Time: 8 a..., (301) 435-1747, rosenzweign@csr.nih.gov . Name of Committee: Immunology Integrated Review Group; Transplantation, Tolerance, and Tumor Immunology Study Section. Date: February 4-5, 2010. Time: 8 a.m. to 4...

  11. 78 FR 58323 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-23

    ... Epidemiology Integrated Review Group, Epidemiology of Cancer Study Section. Date: October 17-18, 2013. Time: 8..., Bethesda, MD 20892, (301) 437- 3478, wieschd@csr.nih.gov . Name of Committee: Immunology Integrated Review Group, Cellular and Molecular Immunology--B Study Section. Date: October 17-18, 2013. Time: 8:30 a.m....

  12. 76 FR 22907 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-04-25

    ....hunnicutt@nih.gov . Name of Committee: Oncology 1-Basic Translational Integrated Review Group; Cancer...-402-5671, zhengli@csr.nih.gov . Name of Committee: Immunology Integrated Review Group; Transplantation, Tolerance, and Tumor Immunology Study Section. Date: June 2-3, 2011. Time: 8 a.m. to 2:30 p.m. Agenda:...

  13. 76 FR 35454 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-17

    ..., Fellowships: Immunology. Date: July 21-22, 2011. Time: 8 a.m. to 2 p.m. Agenda: To review and evaluate grant... Cancer Study Section. Date: July 21, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate...

  14. 76 FR 24891 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-03

    ... Committee: Oncology 1-Basic Translational Integrated Review Group, Cancer Genetics Study Section. Date: June..., Bethesda, MD 20892, (301) 435-1239, guthriep@csr.nih.gov . Name of Committee: Immunology Integrated Review..., Bethesda, MD 20892, 301-496-8551, ingrahamrh@mail.nih.gov . Name of Committee: Immunology Integrated...

  15. 75 FR 19982 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-16

    ... Emphasis Panel; Member Conflict: Cancer Prevention. Date: May 10, 2010. Time: 1 p.m. to 4 p.m. Agenda: To... Clinical Integrated Review Group; Basic Mechanisms of Cancer Therapeutics Study Section. Date: May 24-25...-435-1159, rubinsteinal@csr.nih.gov . Name of Committee: Immunology Integrated Review...

  16. 76 FR 573 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-05

    ..., Cancer Immunopathology and Immunotherapy Study Section. Date: February 3-4, 2011. Time: 8 a.m. to 5 p.m...: Immunology Integrated Review Group, Transplantation, Tolerance, and Tumor Immunology Study Section. Date...: Immunology Integrated Review Group, Immunity and Host Defense Study Section. Date: February 3-4, 2011....

  17. 75 FR 32958 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-06-10

    ... Business: Cancer Diagnostic and Treatment. Date: June 29-30, 2010. Time: 8 a.m. to 5 p.m. Agenda: To review... Scientific Review Special Emphasis Panel; Fellowships: Immunology. Date: June 29, 2010. Time: 1 p.m. to 3...

  18. 77 FR 28890 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-16

    ... 20892, 301-408-9129, lewisdeb@csr.nih.gov . Name of Committee: Immunology Integrated Review Group; Cellular and Molecular Immunology--A Study Section. Date: June 7-8, 2012. Time: 8:30 a.m. to 3:00 p.m...: Population Sciences and Epidemiology Integrated Review Group; Epidemiology of Cancer Study Section....

  19. 77 FR 31625 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-29

    ... Emphasis Panel; Small Business: Sensory Technologies. Date: June 21-22, 2012. Time: 8:00 a.m. to 5:00 p.m... and Behavioral Processes Integrated Review Group, Motor Function, Speech and Rehabilitation Study... and Development. Date: June 22, 2012. Time: 4:00 p.m. to 5:00 p.m. Agenda: To review and...

  20. 77 FR 54582 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-05

    ..., ] Behavioral Genetics and Epidemiology Study Section. Date: October 5, 2012. Time: 8:30 a.m. to 6 p.m. Agenda... Committee: Biobehavioral and Behavioral Processes Integrated Review Group, Cognition and Perception Study...: Biobehavioral and Behavioral Processes Integrated Review Group, Biobehavioral Mechanisms of Emotion, Stress...

  1. 76 FR 370 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-04

    ... Epidemiology Integrated Review Group; Behavioral Genetics and Epidemiology Study Section. Date: February 2... for Scientific Review Special Emphasis Panel; Collaborative: Behavioral Genetics and Epidemiology... 20892, 301-435-2270, wanimaqs@csr.nih.gov . Name of Committee: Genes, Genomes, and Genetics...

  2. 77 FR 32649 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-01

    ... Committee: Biological Chemistry and Macromolecular Biophysics Integrated Review Group; Synthetic and Biological Chemistry A Study Section. Date: June 25, 2012. Time: 8:00 a.m. to 7:00 p.m. Agenda: To review and..., (301) 435-1786, pelhamj@csr.nih.gov . Name of Committee: Biological Chemistry and...

  3. 78 FR 7791 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-04

    ....m. Agenda: To review and evaluate grant applications. Place: Doubletree Hotel Washington, 1515 Rhode... a.m. Agenda: To review and evaluate grant applications. Place: Washington Plaza Hotel, 10 Thomas... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  4. 75 FR 57475 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-21

    ... Molecular Biology of Neurodegeneration Study Section. Date: October 14-15, 2010. Time: 8:30 a.m. to 5 p.m...; Member Conflict: Cell Biology. Date: October 26-27, 2010. Time: 8 a.m. to 6 p.m. Agenda: To review and... Committee: Genes, Genomes, and Genetics Integrated Review Group; Ethical, Legal, and Social Implications...

  5. 78 FR 27247 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-09

    ... Neuroscience Integrated Review Group; Pathophysiological Basis of Mental Disorders and Addictions Study Section... Alcohol Study Section. Date: June 3-4, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review and evaluate..., Bethesda, MD 20892, 301-408-9436, fungai.chanetsa@nih.hhs.gov . Name of Committee: Brain Disorders...

  6. 77 FR 54580 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-05

    ...: Musculoskeletal, Oral and Skin Sciences Integrated Review Group, Skeletal Muscle and Exercise Physiology Study...-54581] [FR Doc No: 2012-21748] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health... Integrated Review Group, Health Disparities and Equity Promotion Study Section. Date: October 4-5, 2012....

  7. 77 FR 56661 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-13

    ... Urological Systems Integrated Review Group; Urologic and Genitourinary Physiology and Pathology. Date...-56662] [FR Doc No: 2012-22481] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health... . Name of Committee: Immunology Integrated Review Group; Innate Immunity and Inflammation Study...

  8. 76 FR 54778 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-02

    .... 301-435-1743. smithbf@auburn.edu . Name of Committee: Emerging Technologies and Training Neurosciences... for Scientific Review Special Emphasis Panel, PAR10-174: International Research Ethics Education and... Committee: Brain Disorders and Clinical Neuroscience Integrated Review Group, Clinical Neuroscience...

  9. 76 FR 49779 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-11

    ... Scientific Review Special Emphasis Panel, Small Business: Neuroscience Education. Date: September 20-21, 2011...: Integrative Neuroscience. Date: September 14-15, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate...-435- 1033, hoshawb@csr.nih.gov . Name of Committee: Brain Disorders and Clinical...

  10. 77 FR 2073 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2012-01-13

    ... Integrated Review Group; Basic Mechanisms of Cancer Therapeutics Study Section. Date: February 6-7, 2012... Conflicts: Liver Pathobiology, Toxicology, and Pharmacology. Date: February 6, 2012. Time: 12 p.m. to 3 p.m... Integrated Review Group; Therapeutic Approaches to Genetic Diseases Study Section. Date: February 9,...

  11. 78 FR 9706 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-02-11

    ...: Developmental Pharmacology. Date: March 5-6, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate... Scientific Review Special Emphasis Panel; Member Conflict: Cancer Therapeutics. Date: March 5, 2013. Time:...

  12. 75 FR 26262 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-11

    ...; Pathophysiological Basis of Mental Disorders and Addictions Study Section. Date: June 3, 2010. Time: 8:30 a.m. to 5 p...: To review and evaluate grant applications. Place: Little America Hotel, 500 South Main Street, Salt... Addictions Competitive Revisions. Date: June 3, 2010. Time: 4 p.m. to 5 p.m. Agenda: To review and...

  13. 7 CFR 1c.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Assuring compliance with this policy-research... Secretary of Agriculture PROTECTION OF HUMAN SUBJECTS § 1c.103 Assuring compliance with this policy—research... research covered by the assurance and by § 1c.103 of this Policy has been reviewed and approved by the...

  14. Implementation of a Quality Assurance Program in a new Radiotherapy Center taking as base the TG-40; Implementacion del programa de Garantia de Calidad en un Centro nuevo de Radioterapia tomando como base el TG-40

    Energy Technology Data Exchange (ETDEWEB)

    Marles, A.; Besa, P.; Hecht, P.; Arriagada, L.; Ruz, A.; Garay, C. [Pontificia Universidad Catolica de Chile, Centro de Cancer. Diagonal Paraguay, 319. Santiago (Chile)

    1998-12-31

    The recommended principles in the `Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group 40`, TG-40, have been the base for implementation of the Quality Assurance Program of a modern Radiotherapy service. During its application has been necessary: to initiate its implementation before the equipment installation, assuming the costs of the contracts of the qualified personnel, realizing an initial investment adequate for equipment acquisition necessary for acceptation, commissioning and routinary control, the experienced formation of the personnel in the protocol philosophy, establishing procedures for day by day process which would allow the retrofeeding, the elaboration of templates and opening to changes and adjustments according to the necessities. The experience of two years had been demonstrated that the TG-40: a) It is feasible to be implemented but sometimes no strict totally and it is essential to have qualified personnel and the necessary material resources; b) It does not contains all the necessary for its practical implementation and must be completing with procedures and routine formats which facilitate their application; c) It allows the detection and opportune failure correction in the process; d) It is a continuous process that does not finishes. (Author)

  15. Marshall Island radioassay quality assurance program an overview

    Energy Technology Data Exchange (ETDEWEB)

    Conrado, C.L.; Hamilton, T.F.; Kehl, S.R.; Robison, W.L.; Stoker, A.C.

    1998-09-01

    The Lawrence Livermore National Laboratory has developed an extensive quality assurance program to provide high quality data and assessments in support of the Marshall Islands Dose Assessment and Radioecology Program. Our quality assurance objectives begin with the premise of providing integrated and cost-effective program support (to meet wide-ranging programmatic needs, scientific peer review, litigation defense, and build public confidence) and continue through from design and implementation of large-scale field programs, sampling and sample preparation, radiometric and chemical analyses, documentation of quality assurance/quality control practices, exposure assessments, and dose/risk assessments until publication. The basic structure of our radioassay quality assurance/quality control program can be divided into four essential elements; (1) sample and data integrity control; (2) instrument validation and calibration; (3) method performance testing, validation, development and documentation; and (4) periodic peer review and on-site assessments. While our quality assurance objectives are tailored towards a single research program and the evaluation of major exposure pathways/critical radionuclides pertinent to the Marshall Islands, we have attempted to develop quality assurance practices that are consistent with proposed criteria designed for laboratory accre

  16. 42 CFR 440.260 - Methods and standards to assure quality of services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Methods and standards to assure quality of services. 440.260 Section 440.260 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH... and Limits Applicable to All Services § 440.260 Methods and standards to assure quality of...

  17. 42 CFR 417.940 - Civil action to enforce compliance with assurances.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Civil action to enforce compliance with assurances. 417.940 Section 417.940 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH....940 Civil action to enforce compliance with assurances. The provisions of § 417.163(g) apply...

  18. 78 FR 64224 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-10-28

    ... 20892, 301-435-2365, aitouchea@csr.nih.gov . Name of Committee: AIDS and Related Research Integrated... Health, 6701 Rockledge Drive, Room 4138, MSC 7814, Bethesda, MD 20892, 301-435-1195, Chengy5@csr.nih.gov... 5218, MSC 7852, Bethesda, MD 20892, 301-806- 6596, rubertm@csr.nih.gov . Name of Committee: Center...

  19. 78 FR 36553 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-06-18

    ... research on assessing the role of Stigma in HIV prevention and care. Date: July 10, 2013. Time: 11:00 a.m... 7852, Bethesda, MD 20892, 301-435- 1775, rubertm@csr.nih.gov . Name of Committee: Center for Scientific... Rockledge Drive, Room 4138, MSC 7814, Bethesda, MD 20892, (301)435-1195, Chengy5@csr.nih.gov . Name...

  20. Program review of the USDA Center for Medical, Agricultural and Veterinary Entomology

    Science.gov (United States)

    The USDA-ARS Center for Medical, Agricultural and Veterinary Entomology (CMAVE) has a history that starts in 1932 in Orlando to develop methods to control mosquitoes, including malaria vectors under conditions simulating those of the south Pacific jungles, and other insects affecting man and animals...

  1. Patient-centered outcomes of high-velocity, low-amplitude spinal manipulation for low back pain: a systematic review.

    Science.gov (United States)

    Goertz, C M; Pohlman, K A; Vining, R D; Brantingham, J W; Long, C R

    2012-10-01

    Low back pain (LBP) is a well-recognized public health problem with no clear gold standard medical approach to treatment. Thus, those with LBP frequently turn to treatments such as spinal manipulation (SM). Many clinical trials have been conducted to evaluate the efficacy or effectiveness of SM for LBP. The primary objective of this paper was to describe the current literature on patient-centered outcomes following a specific type of commonly used SM, high-velocity low-amplitude (HVLA), in patients with LBP. A systematic search strategy was used to capture all LBP clinical trials of HVLA using our predefined patient-centered outcomes: visual analogue scale, numerical pain rating scale, Roland-Morris Disability Questionnaire, and the Oswestry Low Back Pain Disability Index. Of the 1294 articles identified by our search, 38 met our eligibility criteria. Like previous SM for LBP systematic reviews, this review shows a small but consistent treatment effect at least as large as that seen in other conservative methods of care. The heterogeneity and inconsistency in reporting within the studies reviewed makes it difficult to draw definitive conclusions. Future SM studies for LBP would benefit if some of these issues were addressed by the scientific community before further research in this area is conducted.

  2. 78 FR 27975 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2013-05-13

    ... . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group; Pregnancy and Neonatology Study Section. Date: June 11, 2013. Time: 8:00 a.m. to 6:00 p.m....

  3. 77 FR 31626 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-29

    ....nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences, Integrated Review Group, Pregnancy and Neonatology Study Section. Date: June 19, 2012. Time: 8:00 a.m. to...

  4. 75 FR 2877 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-19

    ..., sipej@csr.nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group; Pregnancy and Neonatology Study Section. Date: February 10-11, 2010. Time: 8 a.m....

  5. 76 FR 53686 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-29

    ...@csr.nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences...-435- 1781, liuyh@csr.nih.gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Pregnancy and Neonatology Study Section. Date: October 4,...

  6. 76 FR 31619 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-01

    ... Conflict: Autism, Schizophrenia and Addiction. Date: June 22, 2011, Time: 3 p.m. to 5 p.m. Agenda: To... Scientific Review Special Emphasis Panel, Topics in Bacterial Pathogenesis. Date: June 23-24, 2011. Time: 8...

  7. 76 FR 31966 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-02

    ... Development. Date: July 6-7, 2011. Time: 9 a.m. to 6 p.m. Agenda: To review and evaluate grant applications..., Small ] Business: Biobehavioral and Behavioral Processes across the Lifespan. Date: July 7, 2011....

  8. 75 FR 1795 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-13

    ... Sciences Integrated Review Group, Skeletal Biology Development and Disease Study Section. Date: February 10... Emphasis Panel, Risk Prevention and Health Behavior Across the Lifespan. Date: February 18-19, 2010....

  9. 77 FR 62246 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-12

    ... Review Group, Behavioral and Social Consequences of HIV/AIDS Study Section. Date: November 6-7, 2012...: Interventions for Health Promotion and Disease Prevention, in Native American Populations. Date: November...

  10. 77 FR 10539 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-22

    ... Antimicrobial Resistance Overflow. Date: March 1-2, 2012. Time: 9 a.m. to 5 p.m. Agenda: To review and evaluate... 14, 2012. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. BILLING...

  11. 77 FR 31861 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-05-30

    .... Agenda: To review and evaluate grant applications. Place: The River Inn, 924 25th Street NW., Washington... Emphasis Panel; Member Conflict: Teen Relationship Violence. Date: June 20, 2012. Time: 2:00 p.m. to 3:00...

  12. 75 FR 57965 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-23

    ... grant applications. Place: St. Gregory Luxury Hotel & Suites, 2033 M Street, NW., Washington, DC 20036.... Agenda: To review and evaluate grant applications. Place: St. Gregory Luxury Hotel & Suites, 2033...

  13. 75 FR 1793 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-01-13

    ... Committee: Risk, Prevention and Health Behavior Integrated Review Group; Social Psychology, Personality and.... 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393-93.396,...

  14. 75 FR 52009 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-24

    ..., Bethesda, MD 20892, 301-408-9041, claytone@csr.nih.gov . Name of Committee: Genes, Genomes, and Genetics Integrated Review Group, Genomics, Computational Biology and Technology Study Section. Date: October...

  15. 77 FR 60446 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-03

    ...: Language and Communication. Date: October 31-November 1, 2012. Time: 1 p.m. to 5 p.m. Agenda: To review and... Rockledge Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: Julia Krushkal, Ph.D.,...

  16. 77 FR 2986 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-01-20

    ... Pediatric and Fetal Applications. Date: February 15, 2012. Time: 2 p.m. to 5 p.m. Agenda: To review and....gov . Name of Committee: Endocrinology, Metabolism, Nutrition and Reproductive Sciences,...

  17. 76 FR 9354 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-17

    ... Pediatric and Obstetric Pharmacology. Date: March 9, 2011. Time: 12 p.m. to 4 p.m. Agenda: To review and... Panel; Member Conflict: Endocrinology, Metabolism and Reproduction. Date: March 10-11, 2011. Time: 11...

  18. 75 FR 19983 - National Center for Injury Prevention and Control Initial Review Group

    Science.gov (United States)

    2010-04-16

    ... of the peer reviews conducted in response to Fiscal Year 2010 Requests for Applications related to... Preventing Violence and Violence- Related Injury (R01) Agenda items are subject to change as...

  19. 77 FR 56216 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-12

    ... Committee: Oncology 1-Basic Translational Integrated Review Group; Cancer Etiology Study Section. Date..., Bethesda, MD 20892-7844, 301- 435-1033, gaianonr@csr.nih.gov . Name of Committee: Immunology...

  20. 78 FR 28230 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-14

    ... Emphasis Panel; Cancer Diagnostics and Treatments (CDT) SBIR/STTR. Date: June 13-14, 2013. Time: 8:00 a.m....gov . Name of Committee: Immunology Integrated Review Group; Vaccines Against Microbial Diseases...

  1. 78 FR 55086 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-09

    .... Agenda: To review and evaluate grant applications. Place: Washington Plaza Hotel, 10 Thomas Circle NW... Allerton Hotel, 701 North Michigan Avenue, Chicago, IL 60611. Contact Person: Lee S Mann, Ph.D.,...

  2. 76 FR 57064 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-15

    ... Mechanisms of Emotion, Stress and Health Study Section. Date: October 13, 2011. Time: 8 a.m. to 6 p.m. Agenda... Scientific Review Special Emphasis Panel, Computational Modeling and Sciences for Biomedical and...

  3. 77 FR 12598 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-03-01

    ... applications and the discussions could disclose confidential trade secrets or commercial property such as...: Cognition, Perception and Speech. Date: March 20, 2012. Time: 3 p.m. to 4:30 p.m. Agenda: To review...

  4. 77 FR 39499 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-07-03

    ... applications and the discussions could disclose confidential trade secrets or commercial property such as..., Speech and Rehabilitation. Date: July 30, 2012. Time: 1:00 p.m. to 2:30 p.m. Agenda: To review...

  5. Quality assurance in performance assessments

    Energy Technology Data Exchange (ETDEWEB)

    Maul, P.R.; Watkins, B.M.; Salter, P.; Mcleod, R [QuantiSci Ltd, Henley-on-Thames (United Kingdom)

    1999-01-01

    Following publication of the Site-94 report, SKI wishes to review how Quality Assurance (QA) issues could be treated in future work both in undertaking their own Performance Assessment (PA) calculations and in scrutinising documents supplied by SKB (on planning a repository for spent fuels in Sweden). The aim of this report is to identify the key QA issues and to outline the nature and content of a QA plan which would be suitable for SKI, bearing in mind the requirements and recommendations of relevant standards. Emphasis is on issues which are specific to Performance Assessments for deep repositories for radioactive wastes, but consideration is also given to issues which need to be addressed in all large projects. Given the long time over which the performance of a deep repository system must be evaluated, the demonstration that a repository is likely to perform satisfactorily relies on the use of computer-generated model predictions of system performance. This raises particular QA issues which are generally not encountered in other technical areas (for instance, power station operations). The traceability of the arguments used is a key QA issue, as are conceptual model uncertainty, and code verification and validation; these were all included in the consideration of overall uncertainties in the Site-94 project. Additionally, issues which are particularly relevant to SKI include: How QA in a PA fits in with the general QA procedures of the organisation undertaking the work. The relationship between QA as applied by the regulator and the implementor of a repository development programme. Section 2 introduces the discussion of these issues by reviewing the standards and guidance which are available from national and international organisations. This is followed in Section 3 by a review of specific issues which arise from the Site-94 exercise. An outline procedure for managing QA issues in SKI is put forward as a basis for discussion in Section 4. It is hoped that

  6. 78 FR 26376 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-06

    ... Review Group; Cancer Etiology Study Section. Date: May 30, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To...-1323, assamunu@csr.nih.gov . Name of Committee: Immunology Integrated Review Group; Cellular and Molecular Immunology--B Study Section. Date: May 30-31, 2013. Time: 8:30 a.m. to 5:00 p.m. Agenda: To...

  7. PROCEEDINGS OF RIKEN BNL RESEARCH CENTER WORKSHOP, VOLUME 77, RBRC SCIENTIFIC REVIEW COMMITTEE MEETING, OCTOBER 10-12, 2005

    Energy Technology Data Exchange (ETDEWEB)

    SAMIOS, N.P.

    2005-10-10

    The eighth evaluation of the RIKEN BNL Research Center (RBRC) took place on October 10-12, 2005, at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC) were Dr. Jean-Paul Blaizot, Professor Makoto Kobayashi, Dr. Akira Masaike, Professor Charles Young Prescott (Chair), Professor Stephen Sharpe (absent), and Professor Jack Sandweiss. We are grateful to Professor Akira Ukawa who was appointed to the SRC to cover Professor Sharpe's area of expertise. In addition to reviewing this year's program, the committee, augmented by Professor Kozi Nakai, evaluated the RBRC proposal for a five-year extension of the RIKEN BNL Collaboration MOU beyond 2007. Dr. Koji Kaya, Director of the Discovery Research Institute, RIKEN, Japan, presided over the session on the extension proposal. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on higher research efforts. In addition, a special session was held in connection with the RBRC QCDSP and QCDOC supercomputers. Professor Norman H. Christ, a collaborator from Columbia University, gave a presentation on the progress and status of the project, and Professor Frithjof Karsch of BNL presented the first physics results from QCDOC. Although the main purpose of this review is a report to RIKEN Management (Dr. Ryoji Noyori, RIKEN President) on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.

  8. Quality Assurance Training Tracking (QATTS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is metadata documentation for the Quality Assurance Training Tracking System (QATTS) which tracks Quality Assurace training given by R7 QA staff to in-house...

  9. Incorporating student-centered approaches into catchment hydrology teaching: a review and synthesis

    OpenAIRE

    Thompson, S. E.; I. Ngambeki; Troch, P A; Sivapalan, M.; D. Evangelou

    2012-01-01

    As hydrologists confront the future of water resources on a globalized, resource-scarce and human-impacted planet, the educational preparation of future generations of water scientists becomes increasingly important. Although hydrology inherits a tradition of teacher-centered direct instruction – based on lecture, reading and assignment formats – a growing body of knowledge derived from engineering education research suggests that modifications to these methods could firstly improve the quali...

  10. Chromogranin A as serum marker for gastroenteropancreatic neuroendocrine tumors: a single center experience and literature review.

    OpenAIRE

    Christoph J Auernhammer; Christine Spitzweg; Burkhard Göke; Hoffmann, Johannes N.; Herrmann, Karin A.; Alexander Haug; Michael Vogeser; Axel Kuttner; Michael Lauseker; Svenja Nölting

    2012-01-01

    The aim of this study was to assess the clinical sensitivities of the tumor markers chromogranin A (CgA), urinary 5-hydroxyindoleacetic acid (5-HIAA) and alkaline phosphatase (AP) in neuroendocrine tumors (NETs) of the GastroEnteroPancreatic-(GEP-) system depending on tumor primary location and metastatic spread. In a retrospective single-center series, sensitivities were evaluated in serum samples from 110 patients with midgut (n = 62) and pancreatic (n = 48) NETs. CgA levels were analyzed b...

  11. Review of ultra-high density optical storage technologies for big data center

    Science.gov (United States)

    Hao, Ruan; Liu, Jie

    2016-10-01

    In big data center, optical storage technologies have many advantages, such as energy saving and long lifetime. However, how to improve the storage density of optical storage is still a huge challenge. Maybe the multilayer optical storage technology is the good candidate for big data center in the years to come. Due to the number of layers is primarily limited by transmission of each layer, the largest capacities of the multilayer disc are around 1 TB/disc and 10 TB/ cartridge. Holographic data storage (HDS) is a volumetric approach, but its storage capacity is also strictly limited by the diffractive nature of light. For a holographic disc with total thickness of 1.5mm, its potential capacities are not more than 4TB/disc and 40TB/ cartridge. In recent years, the development of super resolution optical storage technology has attracted more attentions. Super-resolution photoinduction-inhibition nanolithography (SPIN) technology with 9 nm feature size and 52nm two-line resolution was reported 3 years ago. However, turning this exciting principle into a real storage system is a huge challenge. It can be expected that in the future, the capacities of 10TB/disc and 100TB/cartridge can be achieved. More importantly, due to breaking the diffraction limit of light, SPIN technology will open the door to improve the optical storage capacity steadily to meet the need of the developing big data center.

  12. Integrating Safety and Mission Assurance in Design

    Science.gov (United States)

    Cianciola, Chris; Crane, Kenneth

    2008-01-01

    This presentation describes how the Ares Projects are learning from the successes and failures of previous launch systems in order to maximize safety and reliability while maintaining fiscal responsibility. The Ares Projects are integrating Safety and Mission Assurance into design activities and embracing independent assessments by Quality experts in thorough reviews of designs and processes. Incorporating Lean thinking into the design process, Ares is also streamlining existing processes and future manufacturing flows which will yield savings during production. Understanding the value of early involvement of Quality experts, the Ares Projects are leading launch vehicle development into the 21st century.

  13. 77 FR 35413 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-06-13

    ... Disposition During Pregnancy. Date: July 9, 2012. Time: 12:00 p.m. to 3:00 p.m. Agenda: To review and evaluate... Emphasis Panel; Member Conflict: Nutrition and Reproduction. Date: July 10-11, 2012. Time: 8:00 a.m. to...

  14. 75 FR 6674 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-10

    ... Emphasis Panel, Stem Cells and Development. Date: March 16, 2010. Time: 12 p.m. to 1:30 p.m. Agenda: To... Business: Drug Discovery and Development. Date: March 1-2, 2010. Time: 8:30 a.m. to 4 p.m. Agenda: To... Research Integrated Review Group, AIDS Discovery and Development of Therapeutics Study Section. Date:...

  15. 76 FR 66075 - Center for Scientific Review Notice of Closed Meetings

    Science.gov (United States)

    2011-10-25

    ... Rockledge Drive, Room 5208, MSC 7852, Bethesda, MD 20892, (301) 435-1165, walkermc@csr.nih.gov . Name of Committee: AIDS and Related Research Integrated Review Group HIV/AIDS Vaccines Study Section. Date: November..., Room 5208, MSC 7852, Bethesda, MD 20892, (301) 435-1165, walkermc@csr.nih.gov . Name of...

  16. 75 FR 41505 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-07-16

    ... Innovative Research Applications. Date: July 29, 2010. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate...-435- 1775, rubertm@csr.nih.gov . This notice is being published less than 15 days prior to the meeting..., Room 6166, MSC 7892, Bethesda, MD 20892, (301) 402- 6297, gravesr@csr.nih.gov . This notice is...

  17. 75 FR 61767 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-10-06

    ...: Biobehavioral and Behavioral Processes Across the Lifespan. Date: November 4-5, 2010. Time: 8 a.m. to 5 p.m... Development. Date: November 10, 2010. Time: 2 p.m. to 4 p.m. Agenda: To review and evaluate grant...

  18. 77 FR 59200 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-26

    ...-408-9098, josephru@csr.nih.gov . Name of Committee: Genes, Genomes, and Genetics Integrated Review..., Bethesda, MD 20892, 301-435- 4511, ronald.adkins@nih.gov . Name of Committee: Genes, Genomes, and Genetics... Panel, Member Conflict: Cardiovascular, Kidney, Obesity and Diabetes Epidemiology. Date: October...

  19. 77 FR 55847 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-09-11

    ...; Psychiatric and Physiological Domains in Mental Diseases. Date: October 11-12, 2012. Time: 8 a.m. to 5 p.m... 20892, 301-408-9115, bsokolov@csr.nih.gov . Name of Committee: Infectious Diseases and Microbiology Integrated Review Group; Clinical Research and Field Studies of Infectious Diseases Study Section....

  20. 76 FR 2914 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-18

    ... . Name of Committee: Musculoskeletal, Oral and Skin Sciences Integrated Review Group; Skeletal Biology... Group; Cellular and Molecular Biology of Neurodegeneration Study Section. Date: February 9-10, 2011.... Place: Marina del Rey Hotel, 13534 Bali Way, Marina del Rey, CA 90292. Contact Person: Fouad A...

  1. 75 FR 76994 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-12-10

    ... applications. Place: Marina del Rey Hotel, 13534 Bali Way, Marina del Rey, CA 90292. ] Contact Person: Pat... grant applications. Place: Marina del Rey Hotel, 13534 Bali Way, Marina del Rey, CA 90292. Contact....walton@nih.hhs.gov . Name of Committee: Cell Biology Integrated Review Group, Molecular and...

  2. 76 FR 55402 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-09-07

    ..., Cellular and Molecular Biology of the Kidney Study Section. Date: October 12, 2011. Time: 8 a.m. to 5 p.m... Cognitive Neuroscience Integrated Review Group, Neurobiology of Motivated Behavior Study Section. Date... Group, Molecular and Integrative Signal Transduction Study Section. Date: October 11-12, 2011. Time: 8...

  3. 78 FR 59361 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-26

    ..., wup4@csr.nih.gov . Name of Committee: Cell Biology Integrated Review Group; Cellular Signaling and... and Molecular Biology of Glia Study Section. Date: October 21, 2013. Time: 8:00 a.m. to 6:00 p.m...-402- 4411, tianbi@csr.nih.gov . Name of Committee: Oncology 1-Basic Translational Integrated...

  4. 75 FR 29354 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-05-25

    ... Integrated Review Group; Social Psychology, Personality and Interpersonal Processes Study Section. Date: June... Special Emphasis Panel; RFA-OD-10-011: ARRA Comparative Effectiveness Research Mentored Career Development...@csr.nih.gov . (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine;...

  5. 78 FR 28599 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-15

    ... Business: Non-HIV Microbial Vaccine Development. Date: June 14, 2013. Time: 8:00 a.m. to 7:00 p.m. Agenda... Genitourinary Organ Development. Date: June 14, 2013. Time: 8:00 a.m. to 6:00 p.m. Agenda: To review...

  6. 78 FR 15729 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-03-12

    ... Conflict: Topics in Virology and Viral Pathogenesis. Date: April 3, 2013. Time: 2:00 p.m. to 5:00 p.m... for Scientific Review Special Emphasis Panel; Member Conflict: Cardiovascular Clinical and... Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306,...

  7. 75 FR 64736 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-10-20

    ... Emphasis Panel; Small Business: Cancer Drug Development and Therapeutics. Date: November 9-10, 2010. Time...; AIDS Immunology and Pathogenesis Study Section. Date: November 15, 2010. Time: 8:30 a.m. to 6 p.m... for Scientific Review Special Emphasis Panel; Immunology and Pathogenesis of HIV/AIDS. Date:...

  8. 78 FR 64513 - Center For Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-10-29

    ...; Translational Research in Diabetes and Obesity. Date: November 20, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To... for Scientific Review Special Emphasis Panel; Small Business: Endocrinology, Metabolism and... Panel; Fellowships: Endocrinology, Metabolism, Nutrition and Reproductive Sciences. Date: November...

  9. 76 FR 4924 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-27

    ... Discovery for the Nervous System. Date: February 17-18, 2011. Time: 8 a.m. to 10 a.m. Agenda: To review and...: Drug Discovery for the Nervous System. Date: February 18, 2011. Time: 11 a.m. to 3 p.m. Agenda:...

  10. 76 FR 28237 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-16

    ... Special Emphasis Panel, Societal and Ethical Issues in Research: Quorum. Date: June 9, 2011. Time: 8 a.m... Review Group, Radiation Therapeutics and Biology Study Section. Date: June 13-14, 2011. Time: 8 a.m. to 5... Emphasis Panel, Member Conflict: Computational Biology. Date: June 14, 2011. Time: 12 p.m. to 3:30...

  11. 76 FR 1622 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-01-11

    ...; Social Psychology, Personality and Interpersonal Processes Study Section. Date: February 10-11, 2011... Emphasis Panel: Nursing and Related Clinical Sciences Overflow. Date: February 10, 2011. Time: 8 a.m. to 6....gov . Name of Committee: Oncology 2--Translational Clinical Integrated Review Group;...

  12. 76 FR 26309 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-06

    ... Pain Neuroscience. Date: June 1-2, 2011. Time: 8 a.m. to 6 p.m. Agenda: To review and evaluate grant..., Dental and Craniofacial Sciences Study Section. Date: June 2-3, 2011. Time: 8 a.m. to 12 p.m. Agenda:T...

  13. 77 FR 48527 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2012-08-14

    ...: Translational Research in Pediatric and Obstetric Pharmacology. Date: September 11, 2012. Time: 12 p.m. to 5 p.m...: Radiation Therapeutics. Date: September 12, 2012. Time: 1 p.m. to 3 p.m. Agenda: To review and...

  14. Leadership in academic health centers in the US: a review of the role and some recommendations.

    Science.gov (United States)

    Weil, Thomas P

    2014-01-01

    The leadership of the US's most complex academic health centers (AHCs)/medical centers requires individuals who possess a high level of clinical, organizational, managerial, and interpersonal skills. This paper first outlines the major attributes desired in a dean/vice president of health affairs before then summarizing the educational opportunities now generally available to train for such leadership and management roles. For the most part, the masters in health administration (MHA), the traditional MBA, and the numerous alternatives primarily available at universities are considered far too general and too lacking in emotional intelligence tutoring to be particularly relevant for those who aspire to these most senior leadership positions. More appropriate educational options for these roles are discussed: (a) the in-house leadership and management programs now underway at some AHCs for those selected early on in their career for future executive-type roles as well as for those who are appointed later on to a chair, directorship or similar position; and (b) a more controversial approach of potentially establishing at one or a few universities, a mid-career, professional program (a maximum of 12 months and therefore, being completed in less time than an MBA) leading to a masters degree in academic health center administration (MHCA) for those who aspire to fill a senior AHC leadership position. The proposed curriculum as outlined herein might be along the lines of some carefully designed masters level on-line, self-teaching modules for the more technical subjects, yet vigorously emphasizing integrate-type courses focused on enhancing personal and professional team building and leadership skills.

  15. Thoughts on Internal and External Quality Assurance

    Science.gov (United States)

    Zhang, Jianxin

    2012-01-01

    Quality assurance of higher education is made up of two parts: internal quality assurance (IQA) and external quality assurance (EQA). Both belong to a union of the coexistence and balance of yin and yang. But in reality there exists a paradox of "confusion of quality assurance (QA) subject consciousness, singularity of social QA and lack of QA…

  16. 10 CFR 71.37 - Quality assurance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Quality assurance. 71.37 Section 71.37 Energy NUCLEAR... Package Approval § 71.37 Quality assurance. (a) The applicant shall describe the quality assurance program... quality assurance program that are applicable to the particular package design under...

  17. 40 CFR 51.363 - Quality assurance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality assurance. 51.363 Section 51... Requirements § 51.363 Quality assurance. An ongoing quality assurance program shall be implemented to discover... impede program performance. The quality assurance and quality control procedures shall be...

  18. Neuropathy in the hemodialysis population: a review of neurophysiology referrals in a tertiary center.

    LENUS (Irish Health Repository)

    O'Regan, John

    2012-01-01

    This was a retrospective observational study of neurophysiology referrals over 8 years from a tertiary referral center in Ireland. A total of 68 of the 73 referrals yielded one or more abnormalities. Thirty-nine (53%) patients had one or more mononeuropathies; iatrogenic mononeuropathies believed to be associated with arterio-venous fistula creation occurred in 15 patients. Polyneuropathy was identified in 43 patients (59%). Access to an experienced neurophysiology department offers valuable insight into dialysis-associated neuropathies, especially when associated with arterio-venous fistulae.

  19. Advancing patient-centered care through transformative educational leadership: a critical review of health care professional preparation for patient-centered care

    Directory of Open Access Journals (Sweden)

    Lévesque MC

    2013-07-01

    Full Text Available Martine C Lévesque,1,2 Richard Bruce Hovey,2,3 Christophe Bedos2,4 1Faculté de médecine, Université de Montréal, Montréal, QC, Canada; 2Division of Oral Health and Society, Faculty of Dentistry, McGill University, Montreal, QC, Canada; 3Faculty of Medicine, University of Calgary, Calgary, AB, Canada; 4Département de médecine sociale et préventive, Faculté de médicine, Université de Montréal, Montréal, QC, Canada Abstract: Following a historical brief on the development of patient-centered care (PCC, we discuss PCC's value and role in counterbalancing the evidence-based movement in health care. We in turn make a case for a philosophical shift in thinking about the PCC concept, one based on a consideration for how knowledge is produced, used, and valued within care provision processes. A “shared epistemology” foundation is presented, defined, and promoted as essential to the authentic and ethical realization of “shared decision making” between patient and health care provider, and, more generally, of PCC. In accordance with these views, this article critically reviews the literature on health care professional education for the development of PCC. We uncover the disturbing ways in which education frequently undermines the development of patient centeredness, despite curricular emphasis on professionalism and ethical PCC. We also establish the need to raise awareness of how dominant approaches to evaluating student or practitioner performance often fail to reinforce or promote patient centeredness. Finally, we identify successful and inspiring cases of teaching and learning experiences that have achieved perspective transformation on PCC and on new ways of providing care. The pertinence of adopting the theoretical foundations of adult transformative learning is argued, and a call to action is proposed to the leadership of health professional educators across all disciplines. Keywords: patient-centered care, health professional

  20. Synopsis of the Review on Space Weather in Latin America: Space Science, Research Networks and Space Weather Center

    Science.gov (United States)

    Denardini, Clezio Marcos; Dasso, Sergio; Gonzalez-Esparza, Americo

    2016-07-01

    The present work is a synopsis of a three-part review on space weather in Latin America. The first paper (part 1) comprises the evolution of several Latin American institutions investing in space science since the 1960's, focusing on the solar-terrestrial interactions, which today is commonly called space weather. Despite recognizing advances in space research in all of Latin America, this part 1 is restricted to the development observed in three countries in particular (Argentina, Brazil and Mexico), due to the fact that these countries have recently developed operational centers for monitoring space weather. The review starts with a brief summary of the first groups to start working with space science in Latin America. This first part of the review closes with the current status and the research interests of these groups, which are described in relation to the most significant works and challenges of the next decade in order to aid in the solving of space weather open issues. The second paper (part 2) comprises a summary of scientific challenges in space weather research that are considered to be open scientific questions and how they are being addressed in terms of instrumentation by the international community, including the Latin American groups. We also provide an inventory of the networks and collaborations being constructed in Latin America, including details on the data processing, capabilities and a basic description of the resulting variables. These instrumental networks currently used for space science research are gradually being incorporated into the space weather monitoring data pipelines as their data provides key variables for monitoring and forecasting space weather, which allow these centers to monitor space weather and issue warnings and alerts. The third paper (part 3) presents the decision process for the spinning off of space weather prediction centers from space science groups with our interpretation of the reason/opportunities that leads to

  1. A workshop on asthma management programs and centers in Brazil: reviewing and explaining concepts

    Directory of Open Access Journals (Sweden)

    Rafael Stelmach

    2015-02-01

    Full Text Available Objective: To report the results of a workshop regarding asthma management programs and centers (AMPCs in Brazil, so that they can be used as a tool for the improvement and advancement of current and future AMPCs. Methods: The workshop consisted of five presentations and the corresponding group discussions. The working groups discussed the following themes: implementation of asthma management strategies; human resources needed for AMPCs; financial resources needed for AMPCs; and operational maintenance of AMPCs. Results: The workshop involved 39 participants, from all regions of the country, representing associations of asthma patients (n = 3, universities (n = 7, and AMPCs (n = 29. We found a direct relationship between a lack of planning and the failure of AMPCs. Based on the experiences reported during the workshop, the common assumptions about AMPCs in Brazil were the importance of raising awareness of managers; greater community participation; interdependence between primary care and specialized care; awareness of regionalization; and use of medications available in the public health system. Conclusions: Brazil already has a core of experience in the area of asthma management programs. The implementation of strategies for the management of chronic respiratory disease and their incorporation into health care system protocols would seem to be a natural progression. However, there is minimal experience in this area. Joint efforts by individuals with expertise in AMPCs could promote the implementation of asthma management strategies, thus speeding the creation of treatment networks, which might have a multiplier effect, precluding the need for isolated centers to start from zero.

  2. A workshop on asthma management programs and centers in Brazil: reviewing and explaining concepts*

    Science.gov (United States)

    Stelmach, Rafael; Neto, Alcindo Cerci; Fonseca, Ana Cristina de Carvalho Fernandez; Ponte, Eduardo Vieira; Alves, Gerardo; Araujo-Costa, Ildely Niedia; Lasmar, Laura Maria de Lima Belizário Facury; de Castro, Luci Keiko Kuromoto; Lenz, Maria Lucia Medeiros; Silva, Paulo; Cukier, Alberto; Alves, Alexssandra Maia; Lima-Matos, Aline Silva; Cardoso, Amanda da Rocha Oliveira; Fernandes, Ana Luisa Godoy; de São-José, Bruno Piassi; Riedi, Carlos Antônio; Schor, Deborah; Peixoto, Décio Medeiros; Brandenburg, Diego Djones; Camillo, Elineide Gomes dos Santos; Serpa, Faradiba Sarquis; Brandão, Heli Vieira; Lima, João Antonio Bonfadini; Pio, Jorge Eduardo; Fiterman, Jussara; Anderson, Maria de Fátima; Cardoso, Maria do Socorro de Lucena; Rodrigues, Marcelo Tadday; Pereira, Marilyn Nilda Esther Urrutia; Antila, Marti; Martins, Sonia Maria; Guimarães, Vanessa Gonzaga Tavares; Mello, Yara Arruda Marques; de Andrade, Wenderson Clay Correia; Salibe-Filho, William; Caldeira, Zelina Maria da Rocha; da Cruz-Filho, Álvaro Augusto Souza; Camargos, Paulo

    2015-01-01

    Objective: To report the results of a workshop regarding asthma management programs and centers (AMPCs) in Brazil, so that they can be used as a tool for the improvement and advancement of current and future AMPCs. Methods: The workshop consisted of five presentations and the corresponding group discussions. The working groups discussed the following themes: implementation of asthma management strategies; human resources needed for AMPCs; financial resources needed for AMPCs; and operational maintenance of AMPCs. Results: The workshop involved 39 participants, from all regions of the country, representing associations of asthma patients (n = 3), universities (n = 7), and AMPCs (n = 29). We found a direct relationship between a lack of planning and the failure of AMPCs. Based on the experiences reported during the workshop, the common assumptions about AMPCs in Brazil were the importance of raising awareness of managers; greater community participation; interdependence between primary care and specialized care; awareness of regionalization; and use of medications available in the public health system. Conclusions: Brazil already has a core of experience in the area of asthma management programs. The implementation of strategies for the management of chronic respiratory disease and their incorporation into health care system protocols would seem to be a natural progression. However, there is minimal experience in this area. Joint efforts by individuals with expertise in AMPCs could promote the implementation of asthma management strategies, thus speeding the creation of treatment networks, which might have a multiplier effect, precluding the need for isolated centers to start from zero. PMID:25750669

  3. 78 FR 27244 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-09

    ... Group; Cellular and Molecular Immunology--A Study Section. Date: June 6-7, 2013. Time: 8:30 a.m. to 5:00... Committee: Vascular and Hematology Integrated Review Group; Vascular Cell and Molecular Biology Study...; Neurobiology of Motivated Behavior Study Section. Date: June 6-7, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda:...

  4. Characteristics and treatment of vascular injuries: a review of 387 cases at a Chinese center

    OpenAIRE

    Li, Zhui; Zhao, Liang; Wang, Kaizhen; Cheng, Jun; Zhao, Yu; Ren, Wei

    2014-01-01

    Objective: To assess clinical characteristics and treatment outcomes of patients with vascular injuries. Materials and methods: We retrospectively reviewed the medical records of 378 consecutive patients with vascular injuries treated at our hospital from January 2000 to December 2012. Basic characteristics (such as gender; age; cause, site, and type of injury; and concomitant injuries) were recorded, and efficacy was compared between treatments for same type/site injuries. Results: Vascular ...

  5. 75 FR 13767 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-03-23

    ...; Member Conflict: Exploratory Research in AIDS Immunology and Pathogenesis. Date: April 7, 2010. Time: 2 p... Innovative Research Applications. Date: April 1, 2010. Time: 11:59 a.m. to 3:30 p.m. Agenda: To review and....333, Clinical Research, 93.306, 93.333, 93.337, 93.393-93.396, 93.837-93.844, 93.846-93.878,...

  6. 75 FR 8370 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2010-02-24

    ... Panel, Program Project: Systems Genetics. Date: March 3-4, 2010. Time: 8 a.m. to 5 p.m. Agenda: To... Grant Applications: Microbial Vaccine Development. Date: March 11-12, 2010. Time: 8:30 a.m. to 4 p.m...: Microbial Vaccine Development. Date: March 12, 2010. Time: 4 p.m. to 6 p.m. Agenda: To review and...

  7. Canadian TCPS and the Enlightenment to Chinese Ethical Review of Multi-center Research%加拿大三大研究理事会政策宣言及对我国多中心伦理审查的启示

    Institute of Scientific and Technical Information of China (English)

    姜鑫; 张雪; 霍原

    2014-01-01

    In 1998 ,Tri-Council Policy Statement (TCPS) was formally adopted .In 2011 the second edition was passed .It is an important criterion of Canadian multi-center ethical review .TCPS plays an essential role in improving the efficiency and success rate of the multi-center ethical review through the construction of an appropriate decision framework of multi-center ethical review ,the attention to the communication and transparency of multi-center ethical review and the assurance of sufficient resources to support the multi-center ethical review process and to properly handle the problems at the operational level .TCPS ,which strengthens the legislation of the multi-center ethical review ,pays attention to coordinate the relationship between parties and ensures the scientific nature of the research project and the education and training of the staff ,can serve as a reference for multi-center ethical review in China .%1998年,三大研究理事会政策宣言(Tri-Council Policy Statement ,TCPS)正式通过,2011年通过了第二版,是加拿大多中心伦理审查领域的重要准则。TCPS通过构建适宜的多中心伦理审查决策框架、注意多中心伦理审查的沟通及透明度、确保充足的资源以支持多中心伦理审查进程以及妥善处理操作层面问题等途径,提高多中心伦理审查的效率与成功率。可以在强化多中心伦理审查立法、注意协调多方关系、确保研究项目的科学性以及对审查人员进行教育培训等方面为我国多中心伦理审查提供借鉴。

  8. Twin anemia polycythemia sequence: a single center experience and literature review.

    Science.gov (United States)

    Moaddab, Amirhossein; Nassr, Ahmed A; Espinoza, Jimmy; Ruano, Rodrigo; Bateni, Zhoobin H; Shamshirsaz, Amir A; Mandy, George T; Welty, Stephen E; Erfani, Hadi; Popek, Edwina J; Belfort, Michael A; Shamshirsaz, Alireza A

    2016-10-01

    Twin anemia polycythemia sequence (TAPS) is defined by significant intertwin hemoglobin discordance without the amniotic fluid discordance that characterizes twin-twin-transfusion syndrome (TTTS) in monochorionic twin pregnancies. TAPS is an uncommon condition which can either occur spontaneously, or following fetoscopic laser ablation for TTTS. This complication is thought to result from chronic transfusion through very small placental anastomoses; however, the pathogenesis of TAPS remains unknown. Consequently, there is no consensus in the management of TAPS. In this article, three cases of TAPS are described and we review the literature on this uncommon pregnancy complication.

  9. Quality Assurance in Open and Distance Education: a Case Study of Kota Open University

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    After a brief analysis of the concept of quality in open and distance education, information technology for quality assurance and Indian initiative for quality improvement, the paper examines the quality assurance measures at Kota Open University under the following areas: planning academic programmes ;developing academic programmes; producing learning materials; implementing programmes; reviewing courses/programmes ; and developing human resources.

  10. Safety and Mission Assurance Knowledge Management Retention: Managing Knowledge for Successful Mission Operations

    Science.gov (United States)

    Johnson, Teresa A.

    2006-01-01

    Knowledge Management is a proactive pursuit for the future success of any large organization faced with the imminent possibility that their senior managers/engineers with gained experiences and lessons learned plan to retire in the near term. Safety and Mission Assurance (S&MA) is proactively pursuing unique mechanism to ensure knowledge learned is retained and lessons learned captured and documented. Knowledge Capture Event/Activities/Management helps to provide a gateway between future retirees and our next generation of managers/engineers. S&MA hosted two Knowledge Capture Events during 2005 featuring three of its retiring fellows (Axel Larsen, Dave Whittle and Gary Johnson). The first Knowledge Capture Event February 24, 2005 focused on two Safety and Mission Assurance Safety Panels (Space Shuttle System Safety Review Panel (SSRP); Payload Safety Review Panel (PSRP) and the latter event December 15, 2005 featured lessons learned during Apollo, Skylab, and Space Shuttle which could be applicable in the newly created Crew Exploration Vehicle (CEV)/Constellation development program. Gemini, Apollo, Skylab and the Space Shuttle promised and delivered exciting human advances in space and benefits of space in people s everyday lives on earth. Johnson Space Center's Safety & Mission Assurance team work over the last 20 years has been mostly focused on operations we are now beginning the Exploration development program. S&MA will promote an atmosphere of knowledge sharing in its formal and informal cultures and work processes, and reward the open dissemination and sharing of information; we are asking "Why embrace relearning the "lessons learned" in the past?" On the Exploration program the focus will be on Design, Development, Test, & Evaluation (DDT&E); therefore, it is critical to understand the lessons from these past programs during the DDT&E phase.

  11. NARAC SOFTWARE QUALITY ASSURANCE: ADAPTING FORMALISM TO MEET VARYING NEEDS

    Energy Technology Data Exchange (ETDEWEB)

    Walker, H; Nasstrom, J S; Homann, S G

    2007-11-20

    The National Atmospheric Release Advisory Center (NARAC) provides tools and services that predict and map the spread of hazardous material accidentally or intentionally released into the atmosphere. NARAC is a full function system that can meet a wide range of needs with a particular focus on emergency response. The NARAC system relies on computer software in the form of models of the atmosphere and related physical processes supported by a framework for data acquisition and management, user interface, visualization, communications and security. All aspects of the program's operations and research efforts are predicated to varying degrees on the reliable and correct performance of this software. Consequently, software quality assurance (SQA) is an essential component of the NARAC program. The NARAC models and system span different levels of sophistication, fidelity and complexity. These different levels require related but different approaches to SQA. To illustrate this, two different levels of software complexity are considered in this paper. As a relatively simple example, the SQA procedures that are being used for HotSpot, a straight-line Gaussian model focused on radiological releases, are described. At the other extreme, the SQA issues that must be considered and balanced for the more complex NARAC system are reviewed.

  12. Project specific quality assurance plan, W-151, Tank 241-AZ-101 waste retrieval system. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Manthei, M.E.

    1994-11-21

    This project specific quality assurance program plan establishes the responsibility for the implementation of QA requirements, defines and documents the QA requirements associated with design, procurement, and construction, and defines and documents the degree of QA reviews and verifications on the design and construction necessary to assure compliance to project and DOE requirements. Revision 2 updates the QAPP to provide concurrence with approved work scope deletion. In addition, the Quality Assurance Program Index is being updated to reflect the current Quality Assurance Program requirements per DOE Order 5700.6C.

  13. 78 FR 54510 - New Entrant Safety Assurance Program Operational Test

    Science.gov (United States)

    2013-09-04

    ... motor carrier received its USDOT Number. The Agency currently devotes the same resources in travel costs and staff time to on-site reviews of low-risk and higher-risk new entrant motor carriers. The FMCSA... TRANSPORTATION Federal Motor Carrier Safety Administration New Entrant Safety Assurance Program Operational...

  14. Quality Assurance Systems, TQM, and the New Collegialism.

    Science.gov (United States)

    Harvey, Lee

    This report discusses the application of the International Organization for Standards's ISO9000 quality assurance standard and Total Quality Management (TQM) to higher education in light of the "new collegialism." It defines the basic elements of ISO9000 and TQM, reviews the strengths and weaknesses of both approaches, and notes efforts…

  15. A review of zoonotic disease surveillance supported by the Armed Forces Health Surveillance Center.

    Science.gov (United States)

    Burke, R L; Kronmann, K C; Daniels, C C; Meyers, M; Byarugaba, D K; Dueger, E; Klein, T A; Evans, B P; Vest, K G

    2012-05-01

    The Armed Forces Health Surveillance Center (AFHSC), Division of Global Emerging Infections Surveillance and Response System conducts disease surveillance through a global network of US Department of Defense research laboratories and partnerships with foreign ministries of agriculture, health and livestock development in over 90 countries worldwide. In 2010, AFHSC supported zoonosis survey efforts were organized into four main categories: (i) development of field assays for animal disease surveillance during deployments and in resource limited environments, (ii) determining zoonotic disease prevalence in high-contact species which may serve as important reservoirs of diseases and sources of transmission, (iii) surveillance in high-risk human populations which are more likely to become exposed and subsequently infected with zoonotic pathogens and (iv) surveillance at the human-animal interface examining zoonotic disease prevalence and transmission within and between human and animal populations. These efforts have aided in the detection, identification and quantification of the burden of zoonotic diseases such as anthrax, brucellosis, Crimean Congo haemorrhagic fever, dengue fever, Hantaan virus, influenza, Lassa fever, leptospirosis, melioidosis, Q fever, Rift Valley fever, sandfly fever Sicilian virus, sandfly fever Naples virus, tuberculosis and West Nile virus, which are of military and public health importance. Future zoonotic surveillance efforts will seek to develop local capacity for zoonotic surveillance focusing on high risk populations at the human-animal interface.

  16. Long-term outcome on kidney retransplantation: a review of 100 cases from a single center.

    Science.gov (United States)

    Barocci, S; Valente, U; Fontana, I; Tagliamacco, A; Santori, G; Mossa, M; Ferrari, E; Trovatello, G; Centore, C; Lorenzi, S; Rolla, D; Nocera, A

    2009-05-01

    Renal transplantation has become an effective form of treatment for end-stage renal failure. Unfortunately, as a consequence of immunological and nonimmunological pathogenic mechanisms, chronic allograft nephropathy is responsible for the loss of a large proportion of kidney grafts after several years and return to dialysis. We have reported herein our 24 years of experience with second kidney transplantations. Of 1,302 kidney transplantations between January 1983 and June 2007 performed in our transplantation center, 100 were second transplantations. Kidney retransplantation was performed in 74 men and 26 women of overall mean age of 35.4 +/- 12.6 years. Cadaveric donor grafts were transplanted in 92 patients, whereas the remaining 8 were living-related donor kidneys. At 1, 5, and 10 years after kidney transplantation, patient survival rates were 100%, 96%, and 92%, respectively, whereas graft survival rates were 85%, 72%, and 53%, respectively. Immunosuppressive therapy included induction therapy with polyclonal anti-lymphocyte antibodies (ALG/ATG) or (starting from 1999) monoclonal anti CD 25 antibody. Our results demonstrated good outcomes for kidney retransplantations with allocation based on anti- HLA antibody identification together with induction immunosuppression.

  17. A Review of Recent Aeroelastic Analysis Methods for Propulsion at NASA Lewis Research Center

    Science.gov (United States)

    Reddy, T. S. R.; Bakhle, Milind A.; Srivastava, R.; Mehmed, Oral; Stefko, George L.

    1993-01-01

    This report reviews aeroelastic analyses for propulsion components (propfans, compressors and turbines) being developed and used at NASA LeRC. These aeroelastic analyses include both structural and aerodynamic models. The structural models include a typical section, a beam (with and without disk flexibility), and a finite-element blade model (with plate bending elements). The aerodynamic models are based on the solution of equations ranging from the two-dimensional linear potential equation to the three-dimensional Euler equations for multibladed configurations. Typical calculated results are presented for each aeroelastic model. Suggestions for further research are made. Many of the currently available aeroelastic models and analysis methods are being incorporated in a unified computer program, APPLE (Aeroelasticity Program for Propulsion at LEwis).

  18. Near-field microscopy with a scanning nitrogen-vacancy color center in a diamond nanocrystal: A brief review

    CERN Document Server

    Drezet, A; Cuche, A; Mollet, O; Berthel, M; Huant, S

    2015-01-01

    We review our recent developments of near-field scanning optical microscopy (NSOM) that uses an active tip made of a single fluorescent nanodiamond (ND) grafted onto the apex of a substrate fiber tip. The ND hosting a limited number of nitrogen-vacancy (NV) color centers, such a tip is a scanning quantum source of light. The method for preparing the ND-based tips and their basic properties are summarized. Then we discuss theoretically the concept of spatial resolution that is achievable in this special NSOM configuration and find it to be only limited by the scan height over the imaged system, in contrast with the standard aperture-tip NSOM whose resolution depends critically on both the scan height and aperture diameter. Finally, we describe a scheme we have introduced recently for high-resolution imaging of nanoplasmonic structures with ND-based tips that is capable of approaching the ultimate resolution anticipated by theory.

  19. Endovascular Thrombectomy Following Acute Ischemic Stroke: A Single-Center Case Series and Critical Review of the Literature

    Directory of Open Access Journals (Sweden)

    Philip Meyers

    2013-04-01

    Full Text Available Acute ischemic stroke (AIS due to thrombo-embolic occlusion in the cerebral vasculature is a major cause of morbidity and mortality in the United States and throughout the world. Although the prognosis is poor for many patients with AIS, a variety of strategies and devices are now available for achieving recanalization in patients with this disease. Here, we review the treatment options for cerebrovascular thromboembolic occlusion with a focus on the evolution of strategies and devices that are utilized for achieving endovascular clot extraction. In order to demonstrate the progression of this treatment strategy over the past decade, we will also present a single-center case series of AIS patients treated with endovascular thrombectomy.

  20. Chromogranin A as Serum Marker for Gastroenteropancreatic Neuroendocrine Tumors: A Single Center Experience and Literature Review

    Directory of Open Access Journals (Sweden)

    Christoph J. Auernhammer

    2012-02-01

    Full Text Available The aim of this study was to assess the clinical sensitivities of the tumor markers chromogranin A (CgA, urinary 5-hydroxyindoleacetic acid (5-HIAA and alkaline phosphatase (AP in neuroendocrine tumors (NETs of the GastroEnteroPancreatic-(GEP- system depending on tumor primary location and metastatic spread. In a retrospective single-center series, sensitivities were evaluated in serum samples from 110 patients with midgut (n = 62 and pancreatic (n = 48 NETs. CgA levels were analyzed by a commercially-available immunoradiometric assay (CIS-bio during routine follow-up in the years 2000–2009. CgA showed a higher sensitivity for midgut (68% than pancreatic (54% NETs. A higher CgA sensitivity and significantly higher median CgA values were found in patients with liver metastases than in those without, and in patients with hepatic and additionally extra-hepatic metastases than in those with hepatic and nodal metastases alone, respectively. We found an overall sensitivity for elevated 5HIAA excretion of 69% for midgut NETs and a significant correlation between median CgA and 5-HIAA values. The sensitivity of AP and the correlations of AP/CgA-data-pairs were low in both midgut and pancreatic NETs, although highest for metastatic pancreatic NETs. The sensitivity of CgA measurement depends on the NET primary location and spread of disease. 5-HIAA and CgA showed comparable sensitivity in midgut NETs, while AP does not seem to be useful as a tumor marker in GEP-NETs.

  1. Physical aspects of quality assurance in nuclear medicine and radiotherapy, regulatory approach of the National Nuclear Safety Center; Aspectos fisicos de garantia de calidad en medicina nuclear y radioterapia. Enfoque regulatorio del centro Nacional de Seguridad Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez C, D.; Fuente P, A. de la; Quevedo G, J.R.; Lopez F, Y. [CNSN, Calle 28 No. 504 e/5 y 7, Ave. Miramar, La Habana (Cuba); Varela C, C. [CCEEM, Calle 4 No. 455 e/19 y 21, Ave. Vedado, La Habana (Cuba)]. e-mail: cruz@orasen.co.cu

    2006-07-01

    The physical aspects of the quality guarantee in Nuclear Medicine and Radiotherapy its are of cardinal importance to guarantee the quality of the diagnoses and treatments that are carried out to the patients in this type of services. The OIEA, the OMS and other scientific and professional organizations have contributed significantly to the elaboration of recommendations, Protocols, etc. applicable in the quality control programs and safety of the Nuclear Medicine and Radiotherapy departments. In spite of the great effort developed in this sense the Installation of the programs of quality control and safety of the Nuclear Medicine and Radiotherapy departments can fail if the same ones are not based in three decisive elements that are: the existence of national regulations, the existence of the infrastructure required for it and the existence of enough qualified personnel to develop this programs. The present work shows the regulatory focus that on this topic, it has followed the National Center of Nuclear Safety of Cuba (CNSN). The same left of strengthen all the existent Synergies in the different organizations of the country and it went in two fundamental directions: installation of the regulatory requirements that govern this activity and the Authorization of a Cuban Entity, specialized in carrying out audits to the quality control and safety programs of the Nuclear Medicine and Radiotherapy departments. After 4 work years in this direction, the results confirm the validity of the experience developed by the CNSN, at the moment all the services of Nuclear Medicine and Radiotherapy of Cuba possess quality control and safety programs, these programs are annually Auditing by an Authorized entity by the CNSN and the Inspectors of the Regulatory Authority, control, during the inspections, the one execution of the established requirements in the national regulations. The work developed so far can serve, modestly, of reference to others countries of Latin America that

  2. Appreciating the broad clinical features of SMAD4 mutation carriers: a multi-center chart review

    Science.gov (United States)

    Wain, K.E.; Ellingson, M.S.; McDonald, J.; Gammon, A.; Roberts, M.; Pichurin, P.; Winship, I.; Riegert-Johnson, D.; Weitzel, J. N.; Lindor, N.M.

    2014-01-01

    Heterozygous loss-of-function (LOF) SMAD4 mutations are associated with juvenile polyposis syndrome (JP) and hereditary hemorrhagic telangiectasia (HHT). Some carriers exhibit symptoms of both conditions, leading to the name JP-HHT syndrome. Three families have been reported with connective tissue abnormalities. In order to better understand the spectrum and extent of clinical findings in SMAD4 carriers, medical records of 34 patients (20 families) from five clinical practices were reviewed. Twenty-one percent (7/34) had features suggesting a connective tissue defect: enlarged aortic root (n=3), aortic and mitral insufficiency (n=2), aortic dissection (n=1), retinal detachment (n=1), brain aneurysms (n=1), lax skin and joints (n=1). JP-specific findings were almost uniformly present but variable. Ninety-seven percent had colon polyps that were generally pan-colonic and of variable histology and number. Forty-eight percent (15/31) had extensive gastric polyposis. HHT features were documented in 76% including epistaxis (19/31, 61%), mucocutaneous telangiectases (15/31, 48%), liver arteriovenous malformation (AVM) (6/16, 38%), brain AVM (1/26, 4%), pulmonary AVM (9/17, 53%), and intrapulmonary shunting (14/23, 61%). SMAD4 carriers should be managed for JP and HHT, since symptoms of both are likely yet unpredictable. Connective tissue abnormalities are an emerging component of JP-HHT syndrome, and larger studies are needed to understand these manifestations. PMID:24525918

  3. Surgicopathological classification of hepatic space-occupying lesions: A single-center experience with literature review

    Institute of Scientific and Technical Information of China (English)

    Wen-Ming Cong; Hui Dong; Lu Tan; Xu-Xu Sun; Meng-Chao Wu

    2011-01-01

    Accompanying rapid developments in hepatic surgery, the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically. This has led to many changes in the surgicopathological spectrum of PHSOLs, and has contributed to a theoretical basis for modern hepatic surgery and oncological pathology. Between 1982 and 2009 at the Eastern Hepatobiliary Surgery Hospital (EHBH) in Shanghai, 31 901 patients underwent surgery and were diagnosed as having a PHSOL. In this paper, we present an analysis of the PHSOL cases at the EHBH for this time period, along with results from a systematic literature review. We describe a surgicopathological spectrum comprising more than 100 types of PHSOLs that can be stratified into three types: tumor-like, benign, and malignant. We also stratified the PHSOLs into six subtypes derived from hepatocytes; cholangiocytes; vascular, lymphoid and hemopoietic tissues; muscular, fibrous and adipose tissues; neural and neuroendocrine tissues; and miscellaneous tissues. The present study provides a new classification system that can be used as a current reference for clinicians and pathologists to make correct diagnoses and differential diagnoses among various PHSOLs.

  4. [Quality and quality assurance, a European problem].

    Science.gov (United States)

    Schmitt, H

    1994-01-01

    The problem of quality and quality assurance for the free exchange of blood and blood products in Europe is discussed. The background of all discussion of quality is the categorical theory of Aristoteles. The philosophical basis is described. The fundamental law of the daily work of a blood center has to be a philosophy of quality which depends on the sociodemographic situation in the region. This basic varies from country to country in Europe. The importance of the supranational bodies in Europe is mentioned. The weightness of the Code of Ethics is discussed. Virus safety, purity and validity of blood and blood products are described as parameters of the quality aspects. Finally it is confirmed that a well running blood program is a multicategorical problem.

  5. Redefining and expanding quality assurance.

    Science.gov (United States)

    Robins, J L

    1992-12-01

    To meet the current standards of excellence necessary for blood establishments, we have learned from industry that a movement toward organization-wide quality assurance/total quality management must be made. Everyone in the organization must accept responsibility for participating in providing the highest quality products and services. Quality must be built into processes and design systems to support these quality processes. Quality assurance has been redefined to include a quality planning function described as the most effective way of designing quality into processes. A formalized quality planning process must be part of quality assurance. Continuous quality improvement has been identified as the strategy every blood establishment must support while striving for error-free processing as the long-term objective. The auditing process has been realigned to support and facilitate this same objective. Implementing organization-wide quality assurance/total quality management is one proven plan for guaranteeing the quality of the 20 million products that are transfused into 4 million patients each year and for moving toward the new order.

  6. Mission Assurance: Issues and Challenges

    Science.gov (United States)

    2010-07-15

    JFQ), Summer 1995. [9] Alberts , C.J. & Dorofee, A.J., “Mission Assurance Analysis Protocol (MAAP): Assessing Risk in Complex Environments... CAMUS : Automatically Mapping Cyber Assets to Missions and Users,” Proc. of the 2010 Military Communications Conference (MILCOM 2009), 2009. [23

  7. Quality Assurance Program. QAP Workbook.

    Science.gov (United States)

    Pelavin Research Inst., Washington, DC.

    The Quality Assurance Program (QAP) workbook is intended to assist institutions of higher education conduct qualitative and quantitative evaluations of their financial aid operations in relation to requirements of Title IV of the Higher Education Act. The workbook provides a structured approach for incorporating a cyclical Title IV QA system into…

  8. Therapeutic rigid bronchoscopy at a tertiary care center in North India: Initial experience and systematic review of Indian literature

    Directory of Open Access Journals (Sweden)

    Karan Madan

    2014-01-01

    Full Text Available Background and Aim: Rigid bronchoscopy is often an indispensable procedure in the therapeutic management of a wide variety of tracheobronchial disorders. However, it is performed at only a few centers in adult patients in India. Herein, we report our initial 1-year experience with this procedure. Materials and Methods: A prospective observational study on the indications, outcomes, and safety of various rigid bronchoscopy procedures performed between November 2009 and October 2010. Improvement in dyspnea, cough, and the overall quality of life was recorded on a visual analog scale from 0 to 100 mm. A systematic review of PubMed was performed to identify studies reporting the use of rigid bronchoscopy from India. Results: Thirty-eight rigid bronchoscopies (50 procedures were performed in 19 patients during the study period. The commonest indication was benign tracheal stenosis followed by central airway tumor, and the procedures performed were rigid bronchoplasty, tumor debulking, and stent placement. The median procedure duration was 45 (range, 30-65 min. There was significant improvement in quality of life associated with therapeutic rigid bronchoscopy. Minor procedural complications were encountered in 18 bronchoscopies, and there was no procedural mortality. The systematic review identified 15 studies, all on the role of rigid bronchoscopy in foreign body removal. Conclusions: Rigid bronchoscopy is a safe and effective modality for treatment of a variety of tracheobronchial disorders. There is a dire need of rigid bronchoscopy training at teaching hospitals in India.

  9. Transverse arrest: a review of outcomes of rotational forceps and cesarean delivery at a single center.

    Science.gov (United States)

    Leo; Odibo; Ling; Rodis; Borgida; Campbell

    1998-07-01

    Objective: To assess whether Kielland forceps rotational delivery causes a significant increase in maternal or perinatal morbidity in comparison with cesarean delivery in the clinical situation of transverse arrest. Rotational forceps delivery has been reported to have unacceptably high maternal and neonatal complication rates when compared with either spontaneous vaginal delivery or non-rotational forceps delivery. Clinically, however, we considered the more relevant comparison between Kielland rotational forceps delivery and cesarean delivery as these are generally the two modes of delivery for the fetus in transverse arrest.Study Design: The charts of all the mothers delivered by Kielland forceps or cesarean delivery for the main indication of transverse arrest between July 1995 and June 1996 were reviewed. The following were evaluated: Apgar scores at 1 and 5 minutes, cord pH, birth weight, neonatal superficial facial laceration or bruising, bone or nerve injuries, maternal injuries, 3rd and 4th degree perineal or vaginal lacerations, post-partum fever. Statistical analysis was by chi(2) (for Apgar scores), two-tailed Fisher Exact test (for post-partum fever), and t test (for birth weight and cord pH). A P value cesarean deliveries were performed. One-minute Apgar scores of less than or equal to 7 were noted in 11.5% and 6.7% of the forceps and cesarean section groups, respectively (P = NS); mean arterial cord pH was 7.26 for both groups; no cases of post-partum fever were noted in the forceps versus 16% in the cesarean group (P cesarean group, respectively (P cesarean delivery.No significant difference in cord pH and Apgar scores were noted between the two groups. The birth weight was greater and post-partum fever was more common in the cesarean section group. Neonatal facial bruising, temporary facial nerve palsy, and maternal perineal and vaginal lacerations were more common in the forceps groups. This study suggests that rotational forceps may be a

  10. Quality assurance in health care: past, present and future.

    Science.gov (United States)

    Bilawka, E; Craig, B J

    2003-08-01

    Quality of health care delivery is a growing concern globally given current budget restraints and increasing demands on health care providers. The variety of quality assurance and quality management activities equals the numerous ways health care practitioners of all genres provide health care. Dental hygienists around the world must be knowledgeable about quality assurance and management in health care as it is a significant factor in the evolution of the dental hygiene profession and the quality of oral health care provided by dental hygienists. The objective of this research was to conduct a literature review on quality assurance and quality management. A MEDLINE search from 1966 to 2002 was conducted. The search resulted in approximately 145 articles. Additional references from works generated by the search were also obtained. The literature revealed information on the background and history of quality assurance and quality management. Much of the literature was devoted to discussions of the validity, reliability and effectiveness of most prominent quality management activities being utilised in health care today. The investigation revealed numerous issues and barriers surrounding quality management. This article concludes with suggestions for future directions of quality assurance and quality management.

  11. [Quality assurance in head and neck medical oncology].

    Science.gov (United States)

    Digue, Laurence; Pedeboscq, Stéphane

    2014-05-01

    In medical oncology, how can we be sure that the right drug is being administered to the right patient at the right time? The implementation of quality assurance criteria is important in medical oncology, in order to ensure that the patient receives the best treatment safely. There is very little literature about quality assurance in medical oncology, as opposed to radiotherapy or cancer surgery. Quality assurance must cover the entire patient care process, from the diagnosis, to the therapeutic decision and drug distribution, including its selection, its preparation and its delivery to the patient (administration and dosage), and finally the potential side effects and their management. The dose-intensity respect is crucial, and its reduction can negatively affect overall survival rates, as shown in breast and testis cancers for example. In head and neck medical oncology, it is essential to respect the few well-standardized recommendations and the dose-intensity, in a population with numerous comorbidities. We will first review quality assurance criteria for the general medical oncology organization and then focus on head and neck medical oncology. We will then describe administration specificities of head and neck treatments (chemoradiation, radiation plus cetuximab, postoperative chemoradiation, induction and palliative chemotherapy) as well as their follow-up. Lastly, we will offer some recommendations to improve quality assurance in head and neck medical oncology.

  12. Thymic Germinal Centers and Corticosteroids in Myasthenia Gravis: an Immunopathological Study in 1035 Cases and a Critical Review.

    Science.gov (United States)

    Truffault, Frédérique; de Montpreville, Vincent; Eymard, Bruno; Sharshar, Tarek; Le Panse, Rozen; Berrih-Aknin, Sonia

    2017-02-01

    The most common form of Myasthenia gravis (MG) is due to anti-acetylcholine receptor (AChR) antibodies and is frequently associated with thymic pathology. In this review, we discuss the immunopathological characteristics and molecular mechanisms of thymic follicular hyperplasia, the effects of corticosteroids on this thymic pathology, and the role of thymic epithelial cells (TEC), a key player in the inflammatory thymic mechanisms. This review is based not only on the literature data but also on thymic transcriptome results and analyses of pathological and immunological correlations in a vast cohort of 1035 MG patients without thymoma. We show that among patients presenting a thymic hyperplasia with germinal centers (GC), 80 % are females, indicating that thymic follicular hyperplasia is mainly a disease of women. The presence of anti-AChR antibodies is correlated with the degree of follicular hyperplasia, suggesting that the thymus is a source of anti-AChR antibodies. The degree of hyperplasia is not dependent upon the time from the onset, implying that either the antigen is chronically expressed and/or that the mechanisms of the resolution of the GC are not efficiently controlled. Glucocorticoids, a conventional therapy in MG, induce a significant reduction in the GC number, together with changes in the expression of chemokines and angiogenesis. These changes are likely related to the acetylation molecular process, overrepresented in corticosteroid-treated patients, and essential for gene regulation. Altogether, based on the pathological and molecular thymic abnormalities found in MG patients, this review provides some explanations for the benefit of thymectomy in early-onset MG patients.

  13. Quality assurance for environmental analytical chemistry: 1980

    Energy Technology Data Exchange (ETDEWEB)

    Gladney, E.S.; Goode, W.E.; Perrin, D.R.; Burns, C.E.

    1981-09-01

    The continuing quality assurance effort by the Environmental Surveillance Group is presented. Included are all standard materials now in use, their consensus or certified concentrations, quality control charts, and all quality assurance measurements made by H-8 during 1980.

  14. Quality assurance - how to involve the employees

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    1996-01-01

    An overview of strategies for involvement of employees in quality assurance developement and implementation.......An overview of strategies for involvement of employees in quality assurance developement and implementation....

  15. Planning Considerations for Defensive Information Warfare. Information Assurance

    Science.gov (United States)

    2007-11-02

    Systems Agency @ISA) ]oint Interoperability and Engineering Orga&zati&z (‘0) Center for Infomation Systems Security (CBS) Contract No. DCA 100-90-C...military operations. Service assurance features are designed into these systems at every level, [433 and yet they still M to meet even the challenge ...be developed. l Infrastructure design is different than systems design and should be treated as such. l Existing technical and human vulnerabilities

  16. 10 CFR 76.93 - Quality assurance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Quality assurance. 76.93 Section 76.93 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) CERTIFICATION OF GASEOUS DIFFUSION PLANTS Safety § 76.93 Quality assurance. The Corporation shall establish, maintain, and execute a quality assurance program satisfying each...

  17. 40 CFR 31.45 - Quality assurance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Quality assurance. 31.45 Section 31.45... Requirements Reports, Records, Retention, and Enforcement § 31.45 Quality assurance. If the grantee's project... quality assurance practices consisting of policies, procedures, specifications, standards,...

  18. 40 CFR 30.54 - Quality assurance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Quality assurance. 30.54 Section 30.54... NON-PROFIT ORGANIZATIONS Post-Award Requirements Reports and Records § 30.54 Quality assurance. If the... data generation, the grantee shall develop and implement quality assurance practices consisting...

  19. 40 CFR 194.22 - Quality assurance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Quality assurance. 194.22 Section 194... General Requirements § 194.22 Quality assurance. (a)(1) As soon as practicable after April 9, 1996, the Department shall adhere to a quality assurance program that implements the requirements of ASME...

  20. Solar consumer assurance network briefing book

    Energy Technology Data Exchange (ETDEWEB)

    Connor, Lynda

    1980-06-01

    Background information is provided on the rationale and purpose of the Solar Consumer Assurance Network (SOLCAN) program. Mechanisms being instituted by states to meet solar consumer assurance needs are identified. Mechanisms being developed with Federal government support to encourage solar consumer assurance activities are described. The operation of the FY 80 SOLCAN effort is described. (MHR)