WorldWideScience

Sample records for assisted rapid maxillary

  1. [Unilateral surgically assisted rapid maxillary expansion using a transpalatal distractor].

    NARCIS (Netherlands)

    Roelofs, J.; Breuning, K.H.; Spijker, A. van 't; Borstlap, W.A.; Berge, S.J.; Kuijpers-Jagtman, A.M.

    2010-01-01

    A 46-year-old woman was referred for orthodontic surgery consultation because ofa retrognathic maxilla, unilateral cross bite and functional, aesthetic and speech problems. The maxilla was widened unilaterally by unilateral surgically assisted rapid maxillary expansion with a bone-borne transpalatal

  2. Surgically Assisted Rapid Maxillary Expansion: surgical and orthodontic aspects

    NARCIS (Netherlands)

    M.J. Koudstaal (Maarten)

    2008-01-01

    textabstractThe scope of this thesis is to shed more light, from a number of perspectives, on surgically assisted rapid maxillary expansion (SARME). The primary questions this thesis set out to answer were; ‘is there a difference in stability between bone-borne and tooth-borne distraction?’ and ‘can

  3. Dental and skeletal changes following surgically assisted rapid maxillary anterior-posterior expansion.

    Science.gov (United States)

    Ho, Cheng-Ting; Lo, Lun-Jou; Liou, Eric J W; Huang, Chiung Shing

    2008-01-01

    Lengthening the maxillary dental arch as a treatment approach for patients with maxillary deficiency and dental crowding is seldom reported. The purpose of this study was to assess dental and skeletal changes in the maxilla in the correction of maxillary deficiency associated with a retruded maxillary arch using a surgically assisted rapid maxillary anterior-posterior expansion appliance. Predistraction and postraction lateral cephalometric and periapical radiographs and maxillary dental casts of six young adolescents (four boys, two girls, mean age 11 years, 2 months) were examined. These patients received a maxillary anterior segmental osteotomy and distraction osteogenesis with an anteroposteriorly oriented Hyrax expansion appliance based on the biological principles of bone distraction. The retruded dental arch and dental crowding were successfully corrected. Significant forward movement of the point anterior nasal spine, point A, central incisors and first premolars was noted. The maxillary dental arch depth increased an average of 4.2 mm while the arch width remained unchanged. In total, 11.5 mm of dental space was created in the maxillary arch which was sufficient to resolve dental crowding. New bone formation along the distraction site was observed three months after distraction. The use of maxillary anterior segmental osteotomy combined with a Hyrax expansion distraction appliance was effective in arch lengthening and creation of dental space. An overcorrection in this interdental distraction osteogenesis could be a good treatment option for children with maxillary deficiency combined with crowded maxillary dentition.

  4. Maxillary protraction after surgically assisted maxillary expansion

    Directory of Open Access Journals (Sweden)

    Laurindo Zanco Furquim

    2010-06-01

    Full Text Available This case report describes the orthodontic treatment of a 32-year-old woman with a Class III malocclusion, whose chief compliant was her dentofacial esthetics. The pretreatment lateral cephalometric tracings showed the presence of a Class III dentoskeletal malocclusion with components of maxillary deficiency. After discussion with the patient, the treatment option included surgically assisted rapid maxillary expansion (SARME followed by orthopedic protraction (Sky Hook and Class III elastics. Patient compliance was excellent and satisfactory dentofacial esthetics was achieved after treatment completion.

  5. Periodontal and dental effects of surgically assisted rapid maxillary expansion, assessed by using digital study models

    Directory of Open Access Journals (Sweden)

    Danilo Furquim Siqueira

    2015-06-01

    Full Text Available OBJECTIVE: The present study assessed the maxillary dental arch changes produced by surgically assisted rapid maxillary expansion (SARME. METHODS: Dental casts from 18 patients (mean age of 23.3 years were obtained at treatment onset (T1, three months after SARME (T2 and 6 months after expansion (T3. The casts were scanned in a 3D scanner (D-250, 3Shape, Copenhagen, Denmark. Maxillary dental arch width, dental crown tipping and height were measured and assessed by ANOVA and Tukey's test. RESULTS: Increased transversal widths from T1 and T2 and the maintenance of these values from T2 and T3 were observed. Buccal teeth tipping also showed statistically significant differences, with an increase in all teeth from T1 to T2 and a decrease from T2 to T3. No statistically significant difference was found for dental crown height, except for left first and second molars, although clinically irrelevant. CONCLUSION: SARME proved to be an effective and stable procedure, with minimum periodontal hazards.

  6. Transverse Expansion and Stability after Segmental Le Fort I Osteotomy versus Surgically Assisted Rapid Maxillary Expansion: a Systematic Review

    Directory of Open Access Journals (Sweden)

    Thomas Starch-Jensen

    2017-01-01

    Full Text Available Objectives: The objective of the present systematic review was to test the hypothesis of no difference in transverse skeletal and dental arch expansion and relapse after segmental Le Fort I osteotomy versus surgically assisted rapid maxillary expansion. Material and Methods: A MEDLINE (PubMed, Embase and Cochrane library search in combination with a hand-search of relevant journals was conducted by including human studies published in English from January 1, 2000 to June 1, 2016. Results: The search provided 130 titles and four studies fulfilled the inclusion criteria. All the included studies were characterized by high risk of bias and meta-analysis was not possible due to considerable variation. Both treatment modalities significantly increase the transverse maxillary skeletal and dental arch width. The transverse dental arch expansion and relapse seems to be substantial higher with tooth-borne surgically assisted rapid maxillary expansion compared to segmental Le Fort I osteotomy. The ratio of dental to skeletal relapse was significantly higher in the posterior maxilla with tooth-borne surgically assisted rapid maxillary expansion. Moreover, a parallel opening without segment tilting was observed after segmental Le Fort I osteotomy. Conclusions: Maxillary transverse deficiency in adults can be treated successfully with both treatment modalities, although surgically assisted rapid maxillary expansion seems more effective when large transverse maxillary skeletal and dental arch expansion is required. However, considering the methodological limitations of the included studies, long-term randomized studies assessing transverse skeletal and dental expansion and relapse with the two treatment modalities are needed before definite conclusions can be provided.

  7. Evaluation of surgically assisted rapid maxillary expansion with piezosurgery versus oscillating saw and chisel osteotomy - a randomized prospective trial

    Science.gov (United States)

    2013-01-01

    Background Ultrasonic bone-cutting surgery has been introduced as a feasible alternative to the conventional sharp instruments used in craniomaxillofacial surgery because of its precision and safety. The piezosurgery medical device allows the efficient cutting of mineralized tissues with minimal trauma to soft tissues. Piezoelectric osteotome has found its role in surgically assisted rapid maxillary expansion (SARME), a procedure well established to correct transverse maxillary discrepancies. The advantages include minimal risk to critical anatomic structures. The purpose of this clinical comparative study (CIS 2007-237-M) was to present the advantages of the piezoelectric cut as a minimally invasive device in surgically assisted, rapid maxillary expansion by protecting the maxillary sinus mucosal lining. Methods Thirty patients (18 females and 12 males) at the age of 18 to 54 underwent a surgically assisted palatal expansion of the maxilla with a combined orthodontic and surgical approach. The patients were randomly divided into two separate treatment groups. While Group 1 received conventional surgery using an oscillating saw, Group 2 was treated with piezosurgery. The following parameters were examined: blood pressure, blood values, required medication, bleeding level in the maxillary sinus, duration of inpatient stay, duration of surgery and height of body temperature. Results The results displayed no statistically significant differences between the two groups regarding laboratory blood values and inpatient stay. The duration of surgery revealed a significant discrepancy. Deploying piezosurgery took the surgeon an average of 10 minutes longer than working with a conventional-saw technique. However, the observation of the bleeding level in the paranasal sinus presented a major and statistically significant advantage of piezosurgery: on average the bleeding level was one category above the one of the remaining patients. Conclusion This method of piezoelectric

  8. A systematic review of the effects of bone-borne surgical assisted rapid maxillary expansion.

    NARCIS (Netherlands)

    Verstraaten, J.; Kuijpers-Jagtman, A.M.; Mommaerts, M.Y.; Berge, S.J.; Nada, R.; Schols, J.G.J.H.

    2010-01-01

    INTRODUCTION: A systematic literature review was conducted to find out if bone-borne maxillary expansion with corticotomies is an effective and secure orthodontic/orthopaedic treatment modality, eliminating orthodontic and periodontal side effects of tooth-borne maxillary expansion with

  9. The effect of surgically assisted rapid maxillary expansion on sleep architecture: an exploratory risk study in healthy young adults.

    Science.gov (United States)

    Bach, N; Tuomilehto, H; Gauthier, C; Papadakis, A; Remise, C; Lavigne, F; Lavigne, G J; Huynh, N

    2013-11-01

    Maxillary transverse deficiencies (MTD) cause malocclusions. Rapid maxillary expansion treatment is commonly used treatment for correcting such deficiencies and has been found to be effective in improving respiration and sleep architecture in children with obstructive sleep apnoea (OSA). However, thus far, the effect of surgically assisted rapid maxillary expansion (SARME) treatment on sleep architecture and breathing of normal subjects has not been assessed. We hypothesised that sleep quality will improve after maxillary expansion treatment. The objective of this study is to access the effect of maxillary expansion treatment on sleep structure and respiratory functions in healthy young adults with severe MTD. This is a prospective and exploratory clinical study. Twenty-eight consecutive young adult patients (15 males and 13 females, mean age 20·6 ± 5·8 years) presenting with severe MTD at the orthodontic examination were recruited into the study. All the participants underwent a standardised SARME procedure (mean expansion 6·5 ± 1·8 and 8·2 ± 1·8 mm, intercanine and intermolar distance, respectively) to correct malocclusion caused by MTD. An overnight in-laboratory polysomnography, before and after the treatment, was performed. The mean follow-up time was 9 months. The main outcome parameters were the changes in sleep architecture, including sleep stages, arousals, slow-wave activity (SWA) and respiratory variables. Before surgery, young adult patients with MTD presented no evidence of sleep breathing problems. At baseline sleep recording, 7 of 28 (25%) had apnoea-hypopnoea index (AHI) ≥ 5 events per hour. No negative effect of the SARME was observed in questionnaires or sleep laboratory parameters. In the patients with a higher baseline AHI (AHI ≥ 5 h of sleep), we observed a reduction in AHI after surgical treatment (P = 0·028). SARME did not have a negative effect on any sleep or respiration parameters in healthy young individuals

  10. Relapse and stability of surgically assisted rapid maxillary expansion, an anatomical biomechanical study

    NARCIS (Netherlands)

    Koudstaal, M.J.; Smeets, J.B.J.; Kleinrensink, G.J.; Schulten, A.J.M.; van der Wal, K.G.H.

    2009-01-01

    Purpose: This anatomic biomechanical study was undertaken to gain insight into the underlining mechanism of tipping of the maxillary segments during transverse expansion using tooth-borne and bone-borne distraction devices. Materials and Methods: An anatomic biomechanical study was performed on 10

  11. Effect of bone-borne rapid maxillary expanders with and without surgical assistance on the craniofacial structures using finite element analysis.

    Science.gov (United States)

    Lee, Seong Cheon; Park, Jae Hyun; Bayome, Mohamed; Kim, Ki Beom; Araujo, Eustaquio A; Kook, Yoon-Ah

    2014-05-01

    The aim of this study was to analyze stress distribution and displacement of the craniofacial structures resulting from bone-borne rapid maxillary expanders with and without surgical assistance using finite element analysis. Five designs of rapid maxillary expanders were made: a tooth-borne hyrax expander (type A); a bone-borne expander (type B); and 3 bone-borne surgically assisted modalities: separation of the midpalatal suture (type C), added separation of the pterygomaxillary sutures (type D), and added LeFort I corticotomy (type E). The geometric nonlinear theory was applied to evaluate the Von Mises stress distribution and displacement. The surgical types C, D, and E demonstrated more transverse movement than did the nonsurgical types A and B. The amounts of expansion were greater in the posterior teeth in types A and B, but in types C, D, and E, the amounts of expansion were greater in the anterior teeth. At the midpalatal suture, the nonsurgical types showed more anterior expansion than did the posterior region, and higher stresses than with the surgical types. Type B showed the highest stresses at the infraorbital margin, anterior and posterior nasal spines, maxillary tuberosity, and pterygoid plate and hamulus. The 3 surgical models showed similar amounts of stress and displacement along the teeth, midpalatal sutures, and craniofacial sutures. Therefore, when using a bone-borne rapid maxillary expander in an adult, it is recommended to assist it with midpalatal suture separation, which requires minimal surgical intervention. Copyright © 2014 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  12. Three-Dimensional Finite Element Analysis of Stress Distribution and Displacement of the Maxilla Following Surgically Assisted Rapid Maxillary Expansion with Tooth- and Bone-Borne Devices.

    Science.gov (United States)

    Dalband, Mohsen; Kashani, Jamal; Hashemzehi, Hadi

    2015-04-01

    The aim of this study was to investigate the displacement and stress distribution during surgically assisted rapid maxillary expansion under different surgical conditions with tooth- and bone-borne devices. Three-dimensional (3D) finite element model of a maxilla was constructed and an expansion force of 100 N was applied to the left and right molars and premolars with tooth-borne devices and the left and right of mid-palatal sutures at the first molar level with bone-borne devices. Five computer-aided design (CAD) models were simulated as follows and surgical procedures were used: G1: control group (without surgery); G2: Le Fort I osteotomy; G3: Le Fort I osteotomy and para-median osteotomy; G4: Le Fort I osteotomy and pterygomaxillary separation; and G5: Le Fort I osteotomy, para-median osteotomy, and pterygomaxillary separation. Maxillary displacement showed a gradual increase from G1 to G5 in all three planes of space, indicating that Le Fort I osteotomy combined with para-median osteotomy and pterygomaxillary separation produced the greatest displacement of the maxilla with both bone- and tooth-borne devices. Surgical relief and bone-borne devices resulted in significantly reduced stress on anchored teeth. Combination of Le Fort I and para-median osteotomy with pterygomaxillary separation seems to be an effective procedure for increasing maxillary expansion, and excessive stress side effects are lowered around the anchored teeth with the use of bone-borne devices.

  13. Short-term skeletal and dental changes following bone-borne versus tooth-borne surgically assisted rapid maxillary expansion: a randomized clinical trial study.

    Science.gov (United States)

    Zandi, Mohammad; Miresmaeili, Amirfarhang; Heidari, Ali

    2014-10-01

    To evaluate and compare the short-term (post-retention) skeletal and dental changes following bone-borne and tooth-borne surgically assisted rapid maxillary expansion (SARME) using cone beam computed tomography (CBCT). In this randomized clinical study, 30 patients with transverse maxillary deficiency underwent either tooth-borne (n = 15) or bone-borne (n = 15) SARME. Before treatment and immediately after the consolidation period, CBCT was obtained and the nasal floor width, interdental root distance, palatal bone width and interdental cusp distance were measured at first premolar and first molar regions of maxilla. Twenty eight patients completed the study protocol. In both tooth-borne (n = 13) and bone-borne (n = 15) groups the highest degree of expansion occurred in the dental arch, followed by palatal bone, and nasal floor (V-shaped widening in coronal dimension). The amount and pattern of expansion was comparable between anterior and posterior maxillary regions in each group (parallel posteroanterior expansion) and between the two groups. Dental and skeletal effects of tooth-borne and bone-borne devices were comparable. The overall complication rate was negligible. Selection of an expansion device should be based on each individual patient's requirements. Future long-term clinical trial studies to evaluate the stability and relapse of these two techniques are recommended. Copyright © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  14. Effects of Pterygomaxillary Separation on Skeletal and Dental Changes After Surgically Assisted Rapid Maxillary Expansion: A Single-Center, Double-Blind, Randomized Clinical Trial.

    Science.gov (United States)

    Ferraro-Bezerra, Marcelo; Tavares, Rodrygo Nunes; de Medeiros, José Rômulo; Nogueira, Alexandre Simões; Avelar, Rafael Linard; Studart Soares, Eduardo Costa

    2017-08-31

    Surgically assisted rapid maxillary expansion (SARME) is a procedure routinely performed to correct transverse maxillary deformities and can be performed with or without pterygomaxillary disjunction (PD). The aim of the present study was to measure the effect of the amount of expansion and stability of SARME with or without PD. We designed and implemented a double-blind, randomized clinical trial. The patients were randomly assigned to 2 groups: group 1, SARME without PD; and group 2, SARME with PD. Cone-beam computed tomography scans were performed at 3 points: baseline (T0), after maxillary expansion (T1), and at the end of the retention period (T2). Dental and bone expansion and dental inclination at the maxillary canine and first molar regions were assessed. Two-way repeated measures analysis of variance was used to evaluate the differences between the 2 groups at the 3 evaluation periods (T0, T1, and T2), using a level of significance of P patients underwent maxillary surgical expansion (group 1, n = 12; and group 2, n = 12). Both techniques promoted a significant transverse dental expansion in the first molar at T2 (with PD, 5.4 mm; vs without PD, 6.4 mm; change, -6.18 mm to 1.48 mm). However, no statistically significant differences were observed between the 2 groups. The tipping molars at T2 remained at a higher level in the SARME, no PD group than in the SARME, PD group (with PD, 2.3°; vs no PD, 4.6° for 3 teeth; change, -12.72° to 5.57°; and with PD, 1.6° vs without PD, 3.6° for 14 teeth; change, -9.96° to 9.83°). SARME with and without PD is a reliable method for obtaining maxillary expansion, with slight differences in the patterns of skeletal and dental alterations. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  15. Evaluation of opening pattern and bone neoformation at median palatal suture area in patients submitted to surgically assisted rapid maxillary expansion (SARME through cone beam computed tomography

    Directory of Open Access Journals (Sweden)

    Daniel Gomes SALGUEIRO

    2015-08-01

    Full Text Available AbstractSurgically assisted rapid maxillary expansion (SARME is the treatment of choice to adult patients even with severe transversal maxillary discrepancies. However, the adequate retention period to achieve the bone remodeling, thus assuring treatment stability, is controversial.Objective To evaluate the opening pattern and bone neoformation process at the midpalatal suture in patients submitted to surgically assisted (SARME through cone beam computed tomography (CBCT.Material and Methods Fourteen patients were submitted to SARME through subtotal Le Fort I osteotomy. Both the opening pattern and the mean bone density at midpalatal suture area to evaluate bone formation were assessed pre- and post-operatively (15, 60 and 180 days through CBCT.Results Type I opening pattern (from anterior to posterior nasal spine occurred in 12 subjects while type II opening pattern (from anterior nasal spine to transverse palatine suture occurred in 2 individuals. The 180-day postoperative mean (PO 180 of bone density value was 49.9% of the preoperative mean (Pre value.Conclusions The opening pattern of midpalatal suture is more related to patients’ age (23.9 years in type I and 33.5 years in type II and surgical technique. It was not possible to observe complete bone formation at midpalatal suture area at the ending of the retention period studied (180 days.

  16. Three Dimensional Finite Element Analysis of Stress Distribution and Displacement of the Maxilla Following Surgically Assisted Rapid Maxillary Expansion with Tooth- and Bone-Borne Devices

    Directory of Open Access Journals (Sweden)

    Mohsen Dalband

    2015-10-01

    Full Text Available Objectives: The aim of this study was to investigate the displacement and stress distri- bution during surgically assisted rapid maxillary expansion under different surgical conditions with tooth- and bone-borne devices.Materials and Methods: Three-dimensional (3D finite element model of a maxilla was constructed and an expansion force of 100 N was applied to the left and right molars and premolars with tooth-borne devices and the left and right of mid-palatal sutures at the first molar level with bone-borne devices. Five CAD models were simulated as fol- lows and surgical procedures were used:  G1: control group (without surgery; G2: Le Fort I osteotomy; G3: Le Fort I osteotomy and para-median osteotomy; G4: Le Fort I osteotomy and pterygomaxillary separation; and G5: Le Fort I osteotomy, para-median osteotomy, and pterygomaxillary separation.Results: Maxillary displacement showed a gradual increase from group 1 to group 5 in all three planes of space, indicating that Le Fort I osteotomy combined with para-me- dian osteotomy and pterygomaxillary separation produced the greatest displacement of the maxilla with both bone- and tooth-borne devices. Surgical relief and bone-borne devices resulted in significantly reduced stress on anchored teeth.Conclusion: Combination of Le Fort I and para-median osteotomy with pterygomaxil-lary separation seems to be an effective procedure for increasing maxillary expansion, and excessive stress side effects are lowered around the anchored teeth with the use of bone-borne devices.

  17. Maxillary Expansion

    OpenAIRE

    Agarwal, Anirudh; Mathur, Rinku

    2010-01-01

    ABSTRACT Maxillary transverse discrepancy usually requires expansion of the palate by a combination of orthopedic and orthodontic tooth movements. Three expansion treatment modalities are used today: rapid maxillary expansion, slow maxillary expansion and surgically assisted maxillary expansion.This article aims to review the maxillary expansion by all the three modalities and a brief on commonly used appliances.

  18. Expansão rápida da maxila cirurgicamente assistida: estudo preliminar Surgically assisted rapid maxillary expasion: a preliminar study

    Directory of Open Access Journals (Sweden)

    Belmiro Cavalcanti do Egito Vasconcelos

    2006-08-01

    Full Text Available A expansão rápida da maxila cirurgicamente assistida é eficiente para o tratamento de deficiências transversais da maxila em pacientes adultos. OBJETIVO: Estudar duas técnicas de expansão rápida da maxila cirurgicamente assistida - com separação ou não dos processos pterigóides. MATERIAL E MÉTODOS: O estudo de coorte contemporânea longitudinal foi composto de 10 pacientes, com 18-40 anos de idade e com discrepância transversa da maxila de mais de 4mm. Dois grupos foram estabelecidos de forma aleatória, cinco pacientes em cada grupo, de acordo com a separação ou não dos processos pterigóides. Além disso, em ambos os grupos, foram realizadas as osteotomias dos pilares zigomáticos e da sutura intermaxilar. A discrepância transversal foi medida em modelos de estudo, uma radiografia cefalométrica póstero-anterior avaliou os planos zigomáticos superior e inferior e a distância inter-tuberes e uma radiografia oclusal avaliou a disjunção intermaxilar no período pré-operatório e 30 dias de pós-operatório. Um período de 7 dias foi aguardado após as osteotomias, antes de iniciar a expansão de um quarto de volta por dia. RESULTADOS: Não houve diferença estatística entre as medidas pré e pós-operatórias. CONCLUSÃO: Há poucos estudos controlados na literatura comparando as duas técnicas de expansão cirúrgica da maxila. Estudos com amostras maiores devem ser realizados.Surgically assisted rapid maxillary expansion is efficient for the treatment of transverse maxillary deficiencies in skeletally mature patients. AIM: To study two techniques for surgically assisted rapid maxillary expansion: with or without pterygoid plate detachment. MATERIAL AND METHODS: A longitudinal cohort study sample including ten patients aged 18-40 years, with a skeletal transverse discrepancy in the maxilla of more than 4 mm. Two groups were established on a randomized basis, five patients in each group, according to the detachment or

  19. Effect of rapid maxillary expansion on sleep characteristics in children

    National Research Council Canada - National Science Library

    Ashok, Navya; Varma, N K Sapna; Ajith, V V; Gopinath, Siby

    2014-01-01

    Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB...

  20. Effect of rapid maxillary expansion on sleep characteristics in children

    National Research Council Canada - National Science Library

    Navya Ashok; N. K. Sapna Varma; V V Ajith; Siby Gopinath

    2014-01-01

    Introduction: Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB...

  1. Maxillary ulceration resulting from using a rapid maxillary expander in a diabetic patient

    OpenAIRE

    Martins Maia, Luiz Guilherme [UNESP; Monini, Andre da Costa [UNESP; Jacob, Helder Baldi; Gandini Júnior, Luiz Gonzaga

    2011-01-01

    One of the characteristics of diabetes mellitus is the exaggerated inflammatory response. The present report shows the reaction from the use of a rapid maxillary expander in a diabetic patient. A 9-year-old child presented an uncommon reaction to the treatment with a rapid maxillary expander, and on follow-up examination, it was discovered that the patient had diabetes mellitus. After controlling the disease, the proposed treatment was used without further incidents. The case calls attention ...

  2. Effect of rapid maxillary expansion on sleep characteristics in children

    OpenAIRE

    Navya Ashok; N. K. Sapna Varma; Ajith, V. V.; Siby Gopinath

    2014-01-01

    Introduction: Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB). Aims and Objectives: The main objective of this study was to evaluate the effects of RME on sleep characteristics in children. Materials and Methods: Polysomnography was done on children of 8-13 years of age before expansion (T0), after expansion (T1) and a...

  3. Effect of rapid maxillary expansion on sleep characteristics in children

    Directory of Open Access Journals (Sweden)

    Navya Ashok

    2014-01-01

    Full Text Available Introduction: Rapid maxillary expansion (RME is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB. Aims and Objectives: The main objective of this study was to evaluate the effects of RME on sleep characteristics in children. Materials and Methods: Polysomnography was done on children of 8-13 years of age before expansion (T0, after expansion (T1 and after a period of 3 months after retention (T2. Bonded rapid maxillary expander was cemented in all children. Inter-molar distance was also measured at T0 and T2. Statistical Analysis: Nonparametric Friedman test was used for comparing the averages of sleep parameters at different time period (T0, T1, T2. Wilcoxon signed ranks test was used for comparing the averages of inter-molar width (T0-T2. P < 0.05 were considered as significant. Results: All children showed an improvement in sleep parameters with an increase in sleep efficiency, decreased in arousal and desaturation index after expansion. Total sleep time showed a statistically significant increase after expansion. A statistically significant increase in inter-molar distance was obtained after expansion. Conclusions: Rapid maxillary expansion is a useful treatment option for improving quality of sleep even in normal children without SDB. It also induces widening of the maxilla, corrects posterior crossbites and improves maxillary and mandibular dental arch coordination.

  4. Effect of rapid maxillary expansion on sleep characteristics in children.

    Science.gov (United States)

    Ashok, Navya; Varma, N K Sapna; Ajith, V V; Gopinath, Siby

    2014-10-01

    Rapid maxillary expansion (RME) is an orthopedic treatment procedure routinely used to treat constricted maxillary arches and also a potential additional treatment in children presenting with sleep-disordered breathing (SDB). The main objective of this study was to evaluate the effects of RME on sleep characteristics in children. Polysomnography was done on children of 8-13 years of age before expansion (T0), after expansion (T1) and after a period of 3 months after retention (T2). Bonded rapid maxillary expander was cemented in all children. Inter-molar distance was also measured at T0 and T2. Nonparametric Friedman test was used for comparing the averages of sleep parameters at different time period (T0, T1, T2). Wilcoxon signed ranks test was used for comparing the averages of inter-molar width (T0-T2). P children showed an improvement in sleep parameters with an increase in sleep efficiency, decreased in arousal and desaturation index after expansion. Total sleep time showed a statistically significant increase after expansion. A statistically significant increase in inter-molar distance was obtained after expansion. Rapid maxillary expansion is a useful treatment option for improving quality of sleep even in normal children without SDB. It also induces widening of the maxilla, corrects posterior crossbites and improves maxillary and mandibular dental arch coordination.

  5. eRME - Rapid Maxillary Expansion in the economic way

    Directory of Open Access Journals (Sweden)

    Sonali Mahadevia

    2011-01-01

    Full Text Available Aim and Objectives: Rapid Maxillary Expansion constitutes a routine clinical procedure in orthodontics, involving separation of mid-palatine suture which is usually done with help of the Hyrax screw. However, because of its high cost, the use has been limited, especially in institutions. So, the purpose of this study was to construct an economical device which can expand the maxillary arch in growing patients. Materials and Methods: Six patients having constricted maxilla and posterior skeletal crossbite were randomly selected from the Department of Orthodontics. A unique, easy and simple alternative device for expanding the maxillary arch called economic Rapid Maxillary Expander (eRME has been fabricated at about one-tenth the cost of the conventional Hyrax. Pre- and post-treatment effects were statistically tested by using paired t-test at 0.05 level of significance. Results and Conclusion: The study results showed an average expansion in canine, premolar and molar regions of 4.4 mm, 6.8 mm and 9.4 mm, respectively, having significant difference pre-and post-treatment. Thus, it shows that maxillary expansion is efficiently possible with the application of this newly constructed device named eRME. This appliance also acts as a fixed retainer to avoid relapse, hence negating the need for a separate retainer.

  6. Longitudinal stability of rapid and slow maxillary expansion

    Directory of Open Access Journals (Sweden)

    Fábio Henrique de Sá Leitão Pinheiro

    2014-12-01

    Full Text Available OBJECTIVE: The aim of this retrospective study was to compare the longitudinal stability of two types of posterior crossbite correction: rapid maxillary expansion (RME and slow maxillary expansion (SME.METHODS: Study casts of 90 adolescent patients were assessed for interdental width changes at three different periods: pretreatment (T1, post-treatment (T2 and at least, five years post-retention (T3. Three groups of 30 patients were established according to the treatment received to correct posterior crossbite: Group A (RME, group B (SME and group C (control- Edgewise therapy only. After crossbite correction, all patients received fixed edgewise orthodontic appliances. Paired t-tests and one-way ANOVA were used to identify significant intra and intergroup changes, respectively (P < 0.05.RESULTS: Except for intercanine distance, all widths increased in groups A and B from T1 to T2. In the long-term, the amount of relapse was not different for groups A and B, except for 3-3 widths which showed greater decrease in group A. However, the percentage of clinically relapsed cases of posterior crossbite was similar for rapid and slow maxillary expansion.CONCLUSION: Rapid and slow maxillary expansion showed similar stability in the long-term.

  7. Three-dimensional analysis of maxillary changes associated with facemask and rapid maxillary expansion compared with bone anchored maxillary protraction.

    Science.gov (United States)

    Hino, Claudia Toyama; Cevidanes, Lucia H S; Nguyen, Tung T; De Clerck, Hugo J; Franchi, Lorenzo; McNamara, James A

    2013-11-01

    Our objectives in this study were to evaluate in 3 dimensions the growth and treatment effects on the midface and the maxillary dentition produced by facemask therapy in association with rapid maxillary expansion (RME/FM) compared with bone-anchored maxillary protraction (BAMP). Forty-six patients with Class III malocclusion were treated with either RME/FM (n = 21) or BAMP (n = 25). Three-dimensional models generated from cone-beam computed tomographic scans, taken before and after approximately 1 year of treatment, were registered on the anterior cranial base and measured using color-coded maps and semitransparent overlays. The skeletal changes in the maxilla and the right and left zygomas were on average 2.6 mm in the RME/FM group and 3.7 mm in the BAMP group; these were different statistically. Seven RME/FM patients and 4 BAMP patients had a predominantly vertical displacement of the maxilla. The dental changes at the maxillary incisors were on average 3.2 mm in the RME/FM group and 4.3 mm in the BAMP group. Ten RME/FM patients had greater dental compensations than skeletal changes. This 3-dimensional study shows that orthopedic changes can be obtained with both RME/FM and BAMP treatments, with protraction of the maxilla and the zygomas. Approximately half of the RME/FM patients had greater dental than skeletal changes, and a third of the RME/FM compared with 17% of the BAMP patients had a predominantly vertical maxillary displacement. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  8. Effects of rapid maxillary expansion on nasal mucociliary clearance.

    Science.gov (United States)

    Babacan, Hasan; Doruk, Cenk; Uysal, Ismail Onder; Yuce, Salim

    2016-03-01

    To evaluate the changes in nasal mucociliary clearance in orthodontic patients after rapid maxillary expansion (RME) therapy. Forty-two children (25 boys and 17 girls) participated in this study. The RME group consisted of 21 patients (mean age, 13.8 years), who had undergone RME at the initiation of orthodontic treatment. The control group consisted of 21 subjects (mean age, 13.6 years), who were attending the department of orthodontics for active orthodontic treatment. The nasal mucociliary clearance was assessed by the saccharin test. Saccharin transit times (STTs) were measured for each treated subject before expansion (T1), after RME (T2), and after a 3-month retention period (T3). Records were obtained at the same time intervals for each group. The STT decreased significantly in the RME group after expansion and retention (P expansion and retention (P maxillary narrowness and without any history of nasal or systemic disease were within normal limits. However, RME increased the mucociliary clearance in patients who had maxillary narrowness, having positive effects on nasal physiology and increasing nasal cavity volume.

  9. Changes in nasal air flow and school grades after rapid maxillary expansion in oral breathing children

    OpenAIRE

    Torre, Hilda; Alarcón, Jose Antonio

    2012-01-01

    Objective: To analyse the changes in nasal air flow and school grades after rapid maxillary expansion (RME) in oral breathing children with maxillary constriction. Material and Methods: Forty-four oral breathing children (mean age 10.57 y) underwent orthodontic RME with a Hyrax screw. Forty-four age-matched children (mean age 10.64 y) with nasal physiological breathing and adequate transverse maxillary dimensions served as the control group. The maxillary widths, nasal air flow assessed via p...

  10. Assessment of changes in smile after rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Ana Paula Morales Cobra de Carvalho

    2012-10-01

    Full Text Available INTRODUCTION: This study evaluated changes in the smile characteristics of patients with maxillary constriction submitted to rapid maxillary expansion (RME. METHODS: The sample consisted of 81 extraoral photographs of maximum smile of 27 patients with mean age of 10 years, before expansion and 3 and 6 months after fixation of the expanding screw. The photographs were analyzed on the software Cef X 2001, with achievement of the following measurements: Transverse smile area, buccal corridors, exposure of maxillary incisors, gingival exposure of maxillary incisors, smile height, upper and lower lip thickness, smile symmetry and smile arch. Statistical analysis was performed by analysis of variance (ANOVA, at a significance level of 5%. RESULTS: RME promoted statistically significant increase in the transverse smile dimension and exposure of maxillary central and lateral incisors; maintenance of right and left side smile symmetry and of the lack of parallelism between the curvature of the maxillary incisal edges and lower lip border. CONCLUSIONS: RME was beneficial for the smile esthetics with the increase of the transverse smile dimension and exposure of maxillary central and lateral incisors.INTRODUÇÃO: esse estudo avaliou as alterações das características do sorriso de pacientes com atresia maxilar submetidos à expansão rápida da maxila (ERM. MÉTODOS: a amostra consistiu de 81 fotografias extrabucais do sorriso máximo de 27 pacientes, com idade média de 10 anos, antes da expansão e aos três e seis meses após a fixação do parafuso expansor. As análises das fotografias foram realizadas por meio do programa Cef X 2001, e as seguintes medidas foram analisadas: dimensão transversal do sorriso, corredores bucais, quantidade de exposição dos incisivos superiores, exposição gengival dos incisivos superiores, altura do sorriso, espessuras dos lábios superior e inferior, simetria e arco do sorriso. As alterações no sorriso durante

  11. Dentoskeletal effects of maxillary protraction in cleft patients with repetitive weekly protocol of alternate rapid maxillary expansions and constrictions.

    Science.gov (United States)

    da Luz Vieira, Gustavo; de Menezes, Luciane Macedo; de Lima, Eduardo Martinelli S; Rizzatto, Susana

    2009-07-01

    To evaluate the amount of maxillary protraction with face mask in complete unilateral cleft lip and palate patients submitted to two distinct rapid maxillary expansion (RME) protocols. The sample consisted of 20 individuals (nine boys and 11 girls; mean age of 10.4 +/- 2.62 years) with unilateral complete cleft lip and palate who had a constricted maxilla in the vertical and transverse dimensions. Ten patients underwent 1 week of RME with screw activation of one complete turn per day, followed by 23 weeks of maxillary protraction (group 1). The other 10 patients underwent 7 weeks of alternate rapid maxillary expansion and constriction, with one complete turn per day, followed by 17 weeks of maxillary protraction (group 2); both groups underwent a total of 6 months of treatment. Cephalometric measurements were taken at different times: pretreatment (T1), soon after RME (T2), and after 6 months of treatment (T3). Each measurement was analyzed with mixed models for repeated measures, and the covariance structure chosen was compound symmetry. The maxilla displaced slightly forward and downward with a counterclockwise rotation; the mandible rotated downward and backward, resulting in an increase in anterior facial height; the sagittal maxillomandibular relationship was improved; the maxillary molars and incisors were protruded and extruded; and the mandibular incisors were retroclined. There was no significant difference between the groups in evaluation time.

  12. Changes in nasal volume of patients undergoing rapid maxillary expansion

    OpenAIRE

    Muniz, Renata Da Fonseca Lacerda E; Mario Cappellette Jr.; Daniela Carlini

    2008-01-01

    Os efeitos da disjunção maxilar na resistência nasal e fluxo aéreo têm sido amplamente discutidos na literatura, com controvérsias. Suas indicações esqueléticas e dentárias parecem estar bem claras. Porém, aquelas puramente rinológicas não são justificadas, porque nem sempre resultados positivos são encontrados. Este estudo teve por finalidade avaliar a repercussão da disjunção maxilar ortopédica no aspecto respiratório e rinológico dos pacientes submetidos a esse procedimento.Rapid maxillary...

  13. Validity of palatal superimposition of 3-dimensional digital models in cases treated with rapid maxillary expansion and maxillary protraction headgear.

    Science.gov (United States)

    Choi, Jin-Il; Cha, Bong-Kuen; Jost-Brinkmann, Paul-Georg; Choi, Dong-Soon; Jang, In-San

    2012-10-01

    The purpose of this study was to evaluate the validity of the 3-dimensional (3D) superimposition method of digital models in patients who received treatment with rapid maxillary expansion (RME) and maxillary protraction headgear. The material consisted of pre- and post-treatment maxillary dental casts and lateral cephalograms of 30 patients, who underwent RME and maxillary protraction headgear treatment. Digital models were superimposed using the palate as a reference area. The movement of the maxillary central incisor and the first molar was measured on superimposed cephalograms and 3D digital models. To determine whether any difference existed between the 2 measuring techniques, intra-class correlation (ICC) and Bland-Altman plots were analyzed. The measurements on the 3D digital models and cephalograms showed a very high correlation in the antero-posterior direction (ICC, 0.956 for central incisor and 0.941 for first molar) and a moderate correlation in the vertical direction (ICC, 0.748 for central incisor and 0.717 for first molar). The 3D model superimposition method using the palate as a reference area is as clinically reliable for assessing antero-posterior tooth movement as cephalometric superimposition, even in cases treated with orthopedic appliances, such as RME and maxillary protraction headgear.

  14. Avaliação cefalométrica da estabilidade pós-expansão rápida da maxila assistida cirurgicamente Cephalometric evaluation of the post surgically assisted rapid maxillary expansion stability

    Directory of Open Access Journals (Sweden)

    Pedro Luis Scattaregi

    2009-10-01

    Full Text Available OBJETIVO: avaliar as possíveis alterações e a estabilidade dentária e esquelética no sentido transversal, bem como as possíveis alterações verticais da face (AFAI, produzidas pela Expansão Rápida da Maxila Assistida Cirurgicamente (ERMAC. MÉTODOS: a amostra selecionada para este estudo retrospectivo foi composta por 60 telerradiografias em norma frontal, de 15 pacientes, sendo 6 do gênero masculino e 9 do gênero feminino, com média de idades de 23 anos e 3 meses. O disjuntor Hyrax foi instalado e o procedimento cirúrgico adotado envolveu a separação da sutura palatina mediana e não-abordagem da sutura pterigomaxilar. A ativação foi realizada do terceiro dias após a cirurgia até o término da expansão, determinada por critérios clínicos. Todos os pacientes foram radiografados nas fases pré-expansão (T1; pós-expansão imediata (T2; 3 meses pós-expansão, com o próprio disjuntor como contenção (T3; e 6 meses pós-expansão, com a placa removível de acrílico como contenção (T4. Medidas lineares foram obtidas a partir dos traçados cefalométricos gerados por um programa computadorizado (Radiocef Studio 2 e analisadas estatisticamente pelos testes de variância (ANOVA e Tukey ao nível de 5% de significância. RESULTADOS E CONCLUSÕES: concluiu-se que a ERMAC produziu aumentos estatisticamente significativos da cavidade nasal, da largura maxilar e da distância intermolares superiores, de T1 para T2, os quais se mantiveram em T3 e T4. A largura facial e as distâncias intermolares inferiores não apresentaram alterações após a ERMAC. Avaliando o comportamento vertical da face, notou-se um aumento da AFAI nas fases T1 para T2, que diminuiu após a contenção de 3 meses (T3 e permaneceu estável em T4, embora aumentada se comparada com T1.AIM: This study evaluated the stability of the dental and skeletal changes produced by the Surgically Assisted Rapid Maxillary Expansion (SARME in transversal and vertical

  15. Analysis of the maxillary dental arch after rapid maxillary expansion in patients with unilateral complete cleft lip and palate.

    Science.gov (United States)

    Ayub, Priscila Vaz; Janson, Guilherme; Gribel, Bruno Frazão; Lara, Tulio Silva; Garib, Daniela Gamba

    2016-05-01

    Although rapid maxillary expansion has been extensively studied in noncleft patients, scarce evidence of maxillary effects is found for patients with oral clefts. Our objective was to evaluate the dentoalveolar effects of rapid maxillary expansion in children with unilateral complete cleft lip and palate compared with noncleft patients. The experimental group included 25 patients with unilateral complete cleft lip and palate and posterior crossbite (9 girls, 16 boys; mean age, 10.6 years). The control group comprised 27 noncleft patients with posterior crossbite (14 boys, 13 girls; mean age, 9.1 years). The experimental group had lip and palate repairs at 3 and 12 months of age, respectively, and maxillary expansion was indicated before a secondary alveolar bone graft. Digital dental models were obtained immediately before expansion and 6 months after expansion with a laser scanner. Canine and posterior tooth inclinations, transversal widths, arch perimeters, arch lengths, palatal depths, and palatal volumes were digitally measured. The paired t test was used for interphase comparisons, and the independent t test was used for intergroup comparisons (P expansion produced buccal tipping of the canines and posterior teeth and significant increases of all maxillary transverse measurements, arch perimeter, palatal volumes, and palatal depths; only arch lengths decreased. No differences were observed between the groups for any measurement, except for intermolar distance. Rapid maxillary expansion produced similar changes in the patients with unilateral complete cleft lip and palate compared with the noncleft patients except for arch length and palatal depth that decreased after expansion in the children with oral clefts. Copyright © 2016 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  16. Modified hyrax splint for rapid maxillary expansion in esthetically concerned patients

    Directory of Open Access Journals (Sweden)

    Sarabjeet Singh Sandhu

    2015-01-01

    Full Text Available The orthodontic treatment of Class III malocclusion with a maxillary deficiency is often treated with maxillary protraction either with or without maxillary expansion. The routine procedure for rapid maxillary expansion includes banding on first premolars/first deciduous molars and the permanent first molars. However in some patients who are esthetically very conscious, banding of the first premolar would not be a good esthetic option. So for such circumstances we have designed a modified hyrax splint, which does not need the first premolars to be banded.

  17. Avaliação das alterações dentárias na maxila em pacientes submetidos à expansão rápida da maxila assistida cirurgicamente sem o envolvimento da sutura pterigomaxilar Assessment of maxillary dental changes in patients submitted to surgically assisted rapid maxillary expansion with no involvement of pterygoid blade

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Pelucio Camara

    2009-12-01

    appliance in patients who underwent surgically assisted rapid maxillary expansion (SARME, as well as the effectiveness of the surgical technique used. The sample was composed of 34 pairs of cast models, of 17 patients - 6 males and 11 females. METHODS: The measurements were performed on cast models, by measuring the changes on the vertical and transversal planes. The surgical procedure used was the lateral osteotomy on maxillary walls with no involvement of the pterygoid blade, osteotomy of nasal spine on dental midline (anterior central incisors, chisel separation of palatine suture, and separation of the nasal septum. The activation was initiated on the third postoperative day, consisting of two activations, one in the morning and another at night. RESULTS: There were statistically significant expansions in the regions of canines, first and second premolars, first molars, and second molars; respectively, 6.03 mm, 9.82 mm, 8.66 mm, 9.72 mm, and 5.67 mm. The evaluation of the behavior of the support teeth of the expansion appliance regarding the inclination of the dental crowns has shown that an asymmetric vestibularization had taken place, because the values found for the first molars were 6.89º (right and 9.56º (left; the values for the first premolars were 4.74º (left and 3.26º (right; this last value was not statistically significant. CONCLUSIONS: The surgical technique used in this research has been shown to be efficient to obtain maxillary transversal alterations, and there was dental-alveolar inclination of the support teeth of the expansion appliance.

  18. Alveolar bone changes after asymmetric rapid maxillary expansion.

    Science.gov (United States)

    Akin, Mehmet; Baka, Zeliha Muge; Ileri, Zehra; Basciftci, Faruk Ayhan

    2015-09-01

    To quantitatively evaluate the effects of asymmetric rapid maxillary expansion (ARME) on cortical bone thickness and buccal alveolar bone height (BABH), and to determine the formation of dehiscence and fenestration in the alveolar bone surrounding the posterior teeth, using cone-beam computed tomography (CBCT). The CBCT records of 23 patients with true unilateral posterior skeletal crossbite (10 boys, 14.06 ± 1.08 years old, and 13 girls, 13.64 ± 1.32 years old) who had undergone ARME were selected from our clinic archives. The bonded acrylic ARME appliance, including an occlusal stopper, was used on all patients. CBCT records had been taken before ARME (T1) and after the 3-month retention period (T2). Axial slices of the CBCT images at 3 vertical levels were used to evaluate the buccal and palatal aspects of the canines, first and second premolars, and first molars. Paired samples and independent sample t-tests were used for statistical comparison. The results suggest that buccal cortical bone thickness of the affected side was significantly more affected by the expansion than was the unaffected side (P ARME significantly reduced the BABH of the canines (P ARME also increased the incidence of dehiscence and fenestration on the affected side. ARME may quantitatively decrease buccal cortical bone thickness and height on the affected side.

  19. Rapid maxillary anterior teeth retraction en masse by bone compression: a canine model

    National Research Council Canada - National Science Library

    Liu, Chufeng; Cao, Yang; Liu, Conghua; Zhang, Jincai; Xu, Pingping

    2011-01-01

    The present study sought to establish an animal model to study the feasibility and safety of rapid retraction of maxillary anterior teeth en masse aided by alveolar surgery in order to reduce orthodontic treatment time...

  20. Management of recurrent otitis media with rapid maxillary expansion: our experience.

    Science.gov (United States)

    De Stefano, A; Baffa, C; Cerrone, D; Mathur, N; Cascini, V; Petrucci, A G; Neri, G

    2009-01-01

    Management of recurrent otitis media with rapid maxillary expansion: our experience. Recurrent otitis media is a frequent problem in the paediatric population. It is commonly associated with adenoid hypertrophy and occasionally with skeletal development syndrome characterised by maxillary anatomical alterations. When this syndrome is present in conjunction with adenoid hypertrophy, surgical management with adenoidectomy and/or myringotomy with ventilation tube positioning does not necessarily ensure a resolution of conductive hearing disorders. We used maxillary rapid expansion in 27 children with a mean age of 7 years affected by recurrent otitis media associated with skeletal development syndrome and adenoid hypertrophy. Rapid maxillary expansion acting directly on the median palatine suture expands the palate and the nasal floor, improving nasal breathing. In addition, maxillary expansion stretches elevator and tensor palatine muscles, helping to restore normal Eustachian tube function, even in the presence of adenoid hypertrophy. In our opinion, rapid maxillary expansion results in an improvement in skeletal-facial abnormalities associated with skeletal development syndrome and it can be considered a valid treatment for preventing recurrent otitis media in children affected by maxillary anatomical alterations.

  1. Evaluation of immediate soft tissue changes after rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Ki Beom Kim

    2012-10-01

    Full Text Available OBJECTIVE: To evaluate immediate soft tissue changes following rapid maxillary expansion (RME in growing patients, using cone beam computed tomography (CBCT. METHODS: Twenty-three consecutive patients (10 male, 13 female treated by RME were selected. Patients were scanned using CBCT prior to placement of the rapid maxillary expander (T0, then immediately following full activation of the appliance (T1. Defined landmarks were then located on the pre- and post-treatment orientated images. Change in landmark position from pre- to post-treatment was then measured. In addition to landmarks, 10 direct measures were made to determine distance change without regard to direction to measure soft tissue change of the lips. RESULTS: Significant transverse expansion was measured on most soft tissue landmark locations. All the measures made showed significant change in the lip position with a lengthening of the vertical dimension of the upper lip, and a generalized decrease of anterior-posterior thickness of both the upper and lower lips. CONCLUSIONS: Significant changes in the soft tissue do occur with RME treatment. There is a transverse widening of the midface, and a thinning of the lips.OBJETIVO: avaliar as mudanças imediatas no tecido mole após a expansão rápida da maxila (ERM em pacientes em fase de crescimento, usando tomografia computadorizada de feixe cônico (TCFC. MÉTODOS: vinte e três pacientes (10 do sexo masculino e 13 do feminino tratados com ERM foram selecionados. Os pacientes foram escaneados por TCFC antes da implantação do expansor maxilar (T0 e imediatamente após a completa ativação do aparelho (T1. Pontos cefalométricos definidos foram localizados nas imagens pré- e pós-tratamento. As mudanças de posição desses pontos do pré- para o pós-tratamento foram, então, analisadas. Adicionalmente aos pontos, 10 medições diretas foram realizadas para determinar a mudança nas distâncias - independentemente da direção - nos

  2. Photographic assessment of nasal morphology following rapid maxillary expansion in children

    OpenAIRE

    Omar Gabriel da Silva Filho; Tulio Silva Lara; Priscila Vaz Ayub; Amanda Sayuri Cardoso Ohashi; Francisco Antônio Bertoz

    2011-01-01

    Objective: The aim of the present study was to use facial analysis to determine the effects of rapid maxillary expansion (RME) on nasal morphology in children in the stages of primary and mixed dentition, with posterior cross-bite. Material and Methods: Facial photographs (front view and profile) of 60 patients in the pre-expansion period, immediate post-expansion period and one year following rapid maxillary expansion with a Haas appliance were evaluated on 2 occasions by 3 experienced ortho...

  3. Changes of pulp-chamber dimensions 1 year after rapid maxillary expansion.

    Science.gov (United States)

    Baratieri, Carolina; Alves, Matheus; Mattos, Cláudia Trindade; Souza, Margareth Maria Gomes de; Ruellas, Antônio Carlos de Oliveira

    2013-04-01

    The purpose of this study was to examine the effect of orthopedic forces on maxillary first molars' and maxillary central incisors' pulp chambers in children having rapid maxillary expansion as the only intervention compared with children having no orthodontic intervention by using cone-beam computed tomography images. In this prospective controlled clinical study, we evaluated 60 maxillary first molars and 60 maxillary central incisors from 30 children (18 boys, 12 girls) in the mixed dentition and during the pubertal growth period. The treated group had rapid maxillary expansion with the Haas expander, followed by 6 months of retention and 6 months of follow-up out of retention; the control group had no intervention during the study. Cone-beam computed tomography scans were taken initially and 1 year after the rapid maxillary expansion active phase. Initially, a 3-dimensional scrolling in all pulp chambers of the evaluated teeth was performed with Dolphin Imaging software (version 11.0; Dolphin Imaging & Management Solutions, Chatsworth, Calif) to describe the incidence of pulp-chamber calcifications. The dimensions of the pulp chambers of the molars and incisors were also investigated. Cross-sectional and longitudinal slices were used for each molar (coronal and axial slices) and incisor (sagittal and axial slices). The area (mm(2)) was obtained from 3 slices of each kind (6 measurements for each tooth). The results suggest that rapid maxillary expansion did not induce new pulp-chamber calcification. Also, it did not interfere in normal pulp-chamber dimension changes of the anchorage molars. The pulp chamber of the central incisors can be expected to be minimally wider 1 year after the therapy. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  4. Molar changes with cervical headgear alone or in combination with rapid maxillary expansion.

    Science.gov (United States)

    Marchiori Farret, Marcel; de Lima, Eduardo Martinelli S; Pereira Araújo, Vanessa; Deon Rizzatto, Susana Maria; Macedo de Menezes, Luciane; Lima Grossi, Marcio

    2008-09-01

    To test the hypothesis that there is no difference in the distal movement of the maxillary first permanent molars when cervical headgear is used alone or in combination with rapid maxillary expansion. The sample was composed of 36 subjects (aged 9 to 13 years), treated in the Faculty of Dentistry, Pontifícia Universidade Cat;aaolica, Rio Grande do Sul, Brazil. The individuals were in good health and in their pubertal growth period. All had Class II division 1 malocclusion. The patients were divided into two groups: group 1 (22 subjects), Class II, with a normal transverse maxilla treated with cervical traction headgear (HG) 400 g 12 h/d, and group 2 (14 subjects), Class II maxillary transverse deficiency treated with rapid maxillary expansion plus cervical traction headgear (RME + HG). An additional group 3 (17 subjects) served as a control group and included individuals with the same characteristics. All subjects had two lateral cephalograms: initial (T1) and progress (T2), taken 6 months later. Differences between T1 and T2 were compared with the Student's t-test, and three groups were compared by the analysis of variance and Tukey multiple comparison test. Results showed greater distal tipping and greater distal movement of the first permanent molars in group 1 (HG) than in group 2 (RME + HG), P .05). The hypothesis was rejected. Cervical traction headgear alone produced greater distal movement effects in maxillary first permanent molars when compared with rapid maxillary expansion associated with cervical headgear.

  5. Rapid maxillary expansion treatment could produce long-term dental arch changes

    NARCIS (Netherlands)

    Ren, Yijin

    2005-01-01

    : Data Sources: Medline, Medline In-Process, LILACS (Latin American and Caribbean Health Sciences Literature), PUBMED, Embase, Web of Science and the Cochrane Library were searched. Search terms were rapid palatal expansion or rapid maxillary expansion (RME) and tooth or dental changes. Reference

  6. Dental and skeletal effects of combined headgear used alone or in association with rapid maxillary expansion.

    Science.gov (United States)

    Farret, Milton Meri Benitez; Lima, Eduardo Martinelli de; Farret, Marcel M; Araújo, Laura Lutz de

    2015-10-01

    The aim of this study was to assess the effects of combined headgear used alone or in association with rapid maxillary expansion, as the first step for Class II malocclusion treatment. The sample comprised 61 patients divided into three groups: Group 1, combined headgear (CH); Group 2, CH + rapid maxillary expansion (CH + RME); and Group 3, control (CG). In Group 1, patients were treated with combined headgear until Class I molar relationship was achieved. In Group 2, the protocol for headgear was the same; however, patients were previously subject to rapid maxillary expansion. Results showed distal displacement of maxillary molars for both experimental groups (p < 0.001), with distal tipping only in Group 1 (CH) (p < 0.001). There was restriction of forward maxillary growth in Group 2 (CH + RME) (p < 0.05) and clockwise rotation of the maxilla in Group 1 (CH) (p < 0.05). Based on the results, it is possible to suggest that treatment with both protocols was efficient; however, results were more significant for Group 2 (CH + RME) with less side effects.

  7. Dental and skeletal effects of combined headgear used alone or in association with rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Milton Meri Benitez Farret

    2015-10-01

    Full Text Available Objective: The aim of this study was to assess the effects of combined headgear used alone or in association with rapid maxillary expansion, as the first step for Class II malocclusion treatment.Methods:The sample comprised 61 patients divided into three groups: Group 1, combined headgear (CH; Group 2, CH + rapid maxillary expansion (CH + RME; and Group 3, control (CG. In Group 1, patients were treated with combined headgear until Class I molar relationship was achieved. In Group 2, the protocol for headgear was the same; however, patients were previously subject to rapid maxillary expansion.Results:Results showed distal displacement of maxillary molars for both experimental groups (p < 0.001, with distal tipping only in Group 1 (CH (p < 0.001. There was restriction of forward maxillary growth in Group 2 (CH + RME (p < 0.05 and clockwise rotation of the maxilla in Group 1 (CH (p < 0.05.Conclusion: Based on the results, it is possible to suggest that treatment with both protocols was efficient; however, results were more significant for Group 2 (CH + RME with less side effects.

  8. An assessment of the maxilla after rapid maxillary expansion using cone beam computed tomography in growing children

    OpenAIRE

    Woller,Jessica L.; Ki Beom Kim; Behrents, Rolf G.; Buschang, Peter H.

    2014-01-01

    INTRODUCTION: With the advent of cone beam computed tomography (CBCT), it is now possible to quantitatively evaluate the effects of rapid maxillary expansion (RME) on the entire maxillary complex in growing patients. OBJECTIVE: The purpose of this study is to use three-dimensional images to evaluate the displacement that occurs at the circummaxillary sutures (frontonasal, zygomaticomaxillary, intermaxillary, midpalatal, and transpalatal sutures) following rapid maxillary expansion in gro...

  9. Surgically assisted rapid palatal expansion: a literature review.

    Science.gov (United States)

    Suri, Lokesh; Taneja, Parul

    2008-02-01

    Transverse maxillomandibular discrepancies are a major component of several malocclusions. Orthopedic and orthodontic forces are used routinely to correct a maxillary transverse deficiency (MTD) in a young patient. Correction of MTD in a skeletally mature patient is more challenging because of changes in the osseous articulations of the maxilla with the adjoining bones. Surgically assisted rapid palatal expansion (SARPE) has gradually gained popularity as a treatment option to correct MTD. It allows clinicians to achieve effective maxillary expansion in a skeletally mature patient. The use of SARPE to treat MTD decreases unwanted effects of orthopedic or orthodontic expansion. Our aim in this article is to present a comprehensive review of the literature, including indications, diagnosis, guidelines for case selection, a brief overview of the surgical techniques, orthodontic considerations, complications, risks, and limitations of SARPE to better aid the clinician in the management of MTD in skeletally mature patients.

  10. Análise da densidade óptica da sutura palatina mediana seis meses após a expansão rápida da maxila assistida cirurgicamente Evaluation of the midpalatal suture optical density six months after surgically assisted rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Mônica Cunha Macedo

    2009-10-01

    Full Text Available OBJETIVO: avaliar a neoformação óssea da sutura palatina mediana por meio da análise de densidade óptica após a expansão rápida da maxila assistida cirurgicamente (ERMAC. MÉTODOS: a amostra estudada consistiu de 16 pacientes, sendo 6 do gênero masculino e 10 do gênero feminino. Todos os pacientes apresentavam atresia maxilar com mordida cruzada posterior e foram submetidos à ERMAC. Foram realizadas radiografias oclusais parciais da região dos incisivos superiores em quatro fases: antes da ERMAC (fase I, após o fim da ativação do parafuso expansor (fase II, três meses após a ativação do parafuso expansor (fase III, e seis meses após a ERMAC (fase IV. Uma escala de alumínio com oito degraus, variando de 1 a 8mm, foi adaptada no extremo das radiografias. A análise da densidade óptica foi feita após a digitalização das radiografias, utilizando-se o software Image Tool® (UTHSCSA, San Antonio, Texas, EUA. Em cada uma dessas fases, duas áreas foram selecionadas e analisadas. A região "A" (anterior mediu 8 x 1mm² e localizou-se a 1,2cm da tangente situada nos incisivos centrais superiores na região da sutura palatina mediana. A região "B" (posterior mediu 5 x 9mm² e localizou-se a 4,3cm da tangente situada nos incisivos centrais superiores na região da sutura palatina mediana. RESULTADOS: na região "A", comparando-se a fase I com a fase II, e a fase I com a fase III, foram encontradas diferenças estatisticamente significativas - p 0,05 entre as fases I e IV.AIM: This study evaluated the new bone formation in the midpalatal suture after surgically assisted rapid maxillary expansion by optical density analysis. METHODS: The sample was comprised by 16 patients (six males and ten females. All patients presented maxillary atresia with posterior crossbite and were submitted to SARME. Maxillary occlusal radiographs were taken at four stages (before SARME, immediately after SARME, three months after SARME and six months

  11. Molar changes with cervical headgear alone or in combination with rapid maxillary expansion

    OpenAIRE

    Farret, Marcel Marchiori; Lima, Eduardo Martinelli Santayana de; Araújo, Vanessa Pereira de; Rizzatto, Susana Maria Deon; Menezes, Luciane Macedo de; Grossi, Márcio Lima

    2008-01-01

    Objective: To test the hypothesis that there is no difference in the distal movement of the maxillary first permanent molars when cervical headgear is used alone or in combination with rapid maxillary expansion. Materials and Methods: The sample was composed of 36 subjects (aged 9 to 13 years), treated in the Faculty of Dentistry, Pontifícia Universidade Católica, Rio Grande do Sul, Brazil. The individuals were in good health and in their pubertal growth period. All had Class II division 1 ma...

  12. Investigation of Oral Candida Albicans Colonization in Patients Treated with Rapid Maxillary Expansion

    Directory of Open Access Journals (Sweden)

    Fundagül Bilgiç

    2017-11-01

    Full Text Available Objective: The purpose of this study was to investigate Candida albicans colonies in the oral microflora of patients treated with rapid maxillary expansion (RME. Materials and Methods: Totally 54 male and female subjects, including 27 using bonded rapid maxillary expander and 27 patients without orthodontic treatment, were entered in the present study. The study group consisted of 27 patients (14 females and 13 males suffering from both maxillary constriction and posterior cross-bite. Patients treated with a rigid acrylic, bonded rapid maxillary expander were evaluated two times using oral rinses: one at baseline (T0 and 2 after palatal spreading out (T1. The data were analyzed using a chi-square test and a Fisher’s exact test. Results: After the use of RME, no significant changes were found between the data showing C. albicans colonies at T0 and at T1 (p=1.964. Conclusion: Our data suggest that the RME therapy and appliance did not cause a significant change in oral C. albicans colonization.

  13. Skeletal alterations associated with the use of bonded rapid maxillary expansion appliance.

    Science.gov (United States)

    Rossi, Moara de; Rossi, Andiara de; Abrão, Jorge

    2011-01-01

    Bonded maxillary expansion appliances have been suggested to control increases in the vertical dimension of the face after rapid maxillary expansion (RME). However, there is still no consensus in the literature about its real skeletal effects. The purpose of this prospective study was to evaluate, longitudinally, the vertical and sagittal cephalometric alterations after RME performed with bonded maxillary expansion appliance. The sample consisted of 26 children, with a mean age of 8.7 years (range: 6.9-10.9 years), with posterior skeletal crossbite and indication for RME. After maxillary expansion, the bonded appliance was used as a fixed retention for 3.4 months, being replaced by a removable retention subsequently. The cephalometric study was performed onto lateral radiographs, taken before treatment was started, and again 6.3 months after removing the bonded appliance. Intra-group comparison was made using paired t test. The results showed that there were no significant sagittal skeletal changes at the end of treatment. There was a small vertical skeletal increase in five of the eleven evaluated cephalometric measures. The maxilla displaced downward, but it did not modify the facial growth patterns or the direction of the mandible growth. Under the specific conditions of this research, it may be concluded that RME with acrylic bonded maxillary expansion appliance did promote signifciant vertical or sagittal cephalometric alterations. The vertical changes found with the use of the bonded appliance were small and probably transitory, similar to those occurred with the use of banded expansion appliances.

  14. Position and stability of the mandibular incisors after rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Darcy Flávio Nouer

    Full Text Available Objective: To make a cephalometric evaluation of the position and stability of the mandibular incisors immediately after rapid maxillaryexpansion and after a containment period of five months. Methods: The sample consisted of 21 schoolchildren, aged between 6 years and 11 months and 11 years, with mixed dentition, posterior reverse articulation (posterior cross bite, and erupted permanent first molars. The children were randomly divided into two groups: Group1 (composed of eleven children, in whom the encapsulated rapid maxilla expander was used, and Group 2 (composed of ten children, inwhom the conventional Hyrax expander was used. Three lateral teleradiographs of each individual were taken: before treatment, after rapid maxillary expansion, and after a containment period of five months. The cephalometric measurements used for analyzing the incisors were: /1.NB, /1-NB, /1-Line I, IMPA and /1-Jr. The data were submitted to the Dalhberg test, to calculate the error of repeatability, and to ANOVA (p<0.05. Results: The result showed significant difference between the adopted mechanics, but showed no difference between the initial measures, those after rapid expansion of the maxilla and final measures for all the distances, except for /1-Jr. Conclusion: Rapid maxillary expansion, using the encapsulated appliance or Hyrax, caused no significant alteration in the distances: /1.NB, /1-NB, /1-Line I, IMPA; before, after rapid maxillary expansion and after containment.

  15. Surgically assisted maxillary expansion in adults: prospective study.

    Science.gov (United States)

    de Freitas, R R; Gonçalves, A J; Moniz, N J; Maciel, F A

    2008-09-01

    The purpose of this research was to carry out a prospective clinical study of patients with transverse maxillary deficiency, orthopaedically expanded after minimum osteotomies of the zygomatic pillars and the median palatine suture, with quantitative assessment of the stability of the transverse dimensions of the maxilla. The distance between the superior canines and the first superior molars was measured six times during the clinical experiment. The desired expansion was achieved by 15 days postoperatively for all patients. After one year of follow-up, clinical measurements showed a relapse rate of 23% in the superior canine area and 18% in the superior first molar area.

  16. Koreksi gigitan terbalik posterior dan anterior dengan alat cekat rapid maxillary expansion dan elastik intermaksila

    Directory of Open Access Journals (Sweden)

    Retno Dewati

    2014-06-01

    Full Text Available Background: Children with anterior and posterior crossbite usually have a complaint in aesthetic and masticatory function. It could caused by bad habits and hereditary factors which made worse condition. Purpose: The purpose of this case report was to report the use of orthodontic appliance rapid maxillary expansion (RPE and intermaxillary elastic to correct posterior and anterior crossbite in teenage patient. Case: A fourteen years-old teenage female patient came to Dental Hospital Dentistry Universitas Airlangga with case of anterior posterior cross bite and unerupted permanent teeth. Case management: The case was treated using orthodontic fixed appliance rapid maxillary expansion (RPE and followed by intermaxillary elastics. The posterior cross bite treatment took 4 weeks used of orthodontic fixed appliance RPE, while, treatment of anterior cross bite which used intermaxillary elactic was done within three month to achieved normal occlusion. Conclusion: This case report showed that the orthodontic appliance rapid maxillary expansion (RPE and intermaxillary elastic could be used to correct posterior and anterior crossbite.Latar belakang: Anak dengan gigitan terbalik anterior dan posterior pada umumnya mempunyai keluhan dalam hal estetik dan fungsi pengunyahan. Kondisi gigitan terbalik biasanya disebabkan oleh adanya kebiasaan buruk dan faktor keturunan yang semakin memperparah keadaan tersebut. Tujuan: Laporan kasus ini melaporkan pemakaian alat cekat rapid maxillary expansion (RPE dan elastik intermaksila untuk mengkoreksi gigitan terbalik posterior dan anterior pada anak remaja. Kasus: Pasien remaja perempuan berusia 14 tahun datang ke Rumah Sakit Gigi dan Mulut Fakultas Kedokteran Gigi Universitas Airlangga Surabaya dengan kasus gigitan terbalik anterior posterior dan terdapat gigi permanen yang tidak tumbuh. Tatalaksana kasus: Perawatan yang dilakukan adalah koreksi gigitan terbalik dengan menggunakan alat ortodonsia cekat rapid maxillary

  17. Modified-casted Appliance for Surgically-assisted Rapid Palatal Expansion: A Clinical Report

    Directory of Open Access Journals (Sweden)

    Puneet Batra

    2014-01-01

    Full Text Available Transverse maxilla-mandibular discrepancies are a major component of several malocclusions. Surgically assisted rapid palatal expansion (SARPE is a common treatment modality for older patients in the correction of a maxillary transverse deficiency. In such cases, retention of the appliance plays an important role and this becomes a problem in patients having enamel hypoplasia. Therefore, the design was modified of a tooth-borne rapid maxillary expansion appliance with provision for miniscrew skeletal anchorage in a Class II malocclusion case having anterior open bite with bilateral posterior crossbite and enamel hypoplasia.

  18. Influence of Orthodontic Rapid Maxillary Expansion on Nocturnal Enuresis in Children

    OpenAIRE

    Lidia Hyla-Klekot; Marek Truszel; Andrzej Paradysz; Lidia Postek-Stefańska; Marcin Życzkowski

    2015-01-01

    Background. The etiology of nocturnal enuresis (NE) is multifactorial and has not been fully explained yet. New ways of treatment are constantly being investigated, including the rapid maxillary expansion (RME). Methods. A total of 41 patients diagnosed with NE were divided into two experimental groups: A and B. Group A included 16 children who have been treated with RME. Group B comprised 25 children who have not undertaken orthodontic treatment. Children from both groups have been monitored...

  19. Comparison between rapid and mixed maxillary expansion through an assessment of arch changes on dental casts.

    Science.gov (United States)

    Grassia, Vincenzo; d'Apuzzo, Fabrizia; Jamilian, Abdolreza; Femiano, Felice; Favero, Lorenzo; Perillo, Letizia

    2015-01-01

    Aim of this retrospective observational study was to compare upper and lower dental changes in patients treated with Rapid Maxillary Expansion (RME) and Mixed Maxillary Expansion (MME), assessed by dental cast analysis. Treatment groups consisted of 42 patients: the RME group (n = 21) consisted of 13 female and 8 male subjects with the mean age of 8.8 years ± 1.37 at T0 and 9.6 years ± 1.45 at T1; the MME group (n = 21) consisted of 12 female and 9 male patients with a mean age of 8.9 years ± 2.34 at T0 and 10.5 years ± 2.08 at T1. The upper and lower arch analysis was performed on four dental bilateral landmarks, on upper and lower casts; also upper and lower arch depths were measured. The groups were compared using independent sample t-test to estimate dental changes in upper and lower arches. Before expansion treatment (T0), the groups were similar for all examined variables (p>0.05). In both RME and MME group, significant increments in all the variables for maxillary and mandibular arch widths were observed after treatment. No significant differences in maxillary and mandibular arch depths were observed at the end of treatment in both groups. An evaluation of the changes after RME and MME (T1) showed statistically significant differences in mandibular arch depth (plip bumper effects" observed in the MME protocol.

  20. Rapid maxillary expansion for the treatment of nasal obstruction in children younger than 12 years.

    Science.gov (United States)

    Monini, Simonetta; Malagola, Caterina; Villa, Maria Pia; Tripodi, Caterina; Tarentini, Silvia; Malagnino, Irene; Marrone, Vania; Lazzarino, Antonio Ivan; Barbara, Maurizio

    2009-01-01

    To assess short- and long-term effects of rapid maxillary expansion (RME) on nasal flow in young children. Since RME has been reported to positively influence nasal obstruction in subjects with respiratory problems by reducing nasal resistance, a similar efficacy of RME could be expected in children with deciduous and/or mixed dentition who are affected by maxillary constriction and nasal obstruction from a different cause. Prospective study of children younger than 12 years, with different grades of malocclusion and oral breathing. Data included active anterior rhinomanometry in both the supine and orthostatic positions, as well as radiographic cephalometric measurements. Tertiary care university hospital. Data were prospectively collected from 2005 to 2007. Nasal flow and resistance were measured in 65 children younger than 12 years, with mixed or deciduous dentition and different grades of malocclusion and oral breathing. Efficacy of RME for resolution of maxillary constriction. After RME, an improvement of nasal flow and resistance has been recorded in patients, in the supine position, who presented both anterior and posterior obstruction. Less notable changes were shown in isolated forms of obstruction and in the orthostatic position. In cases of maxillary constriction and nasal airway obstruction, RME has proved to be efficient for the improvement of nasal respiration in children via a widening effect on the nasopharyngeal cavity.

  1. Prediction of Class II improvement after rapid maxillary expansion in early mixed dentition

    Directory of Open Access Journals (Sweden)

    Alberto Caprioglio

    2017-04-01

    Full Text Available Abstract Background The aim of this study is to identify cephalometric pretreatment parameters for prediction of Class II improvement induced by rapid maxillary expansion. Methods Lateral cephalograms of 30 patients (mean age 8.3 ± 1.6 years old showing Class II molar relationship and undergone to rapid maxillary expansion on the upper deciduous molars were traced before treatment, and molar relation changes were evaluated on dental casts before and after treatment. Overall treatment time lasted 10.2 ± 2 months. Good responders (18 subjects, 10 females and 8 males showed improvement of at least 2.50 mm, and bad responders (12 subjects, 7 females and 5 males showed no improvement, improvement less than 2.50 mm, or worsening of molar relationship after treatment. Student’s t test was used to assess significance of differences between groups, and discriminant analysis allowed identification of predictive pretreatment variables. Results Articular angle, superior gonial angle, and mandibular dimensions (Co-Gn, S-Ar, Ar-Go, Go-Me showed significant differences in the comparison between groups. Mandibular length Co-Gn and superior gonial angle were selected as significant predictive variable for discrimination. Conclusions Patients with smaller mandibular length and more acute superior gonial angle are expected to have more chances to improve molar Class II after rapid maxillary expansion.

  2. Three-dimensional assessment of buccal alveolar bone after rapid and slow maxillary expansion: a clinical trial study.

    Science.gov (United States)

    Brunetto, Mauricio; Andriani, Juliana da Silva Pereira; Ribeiro, Gerson Luiz Ulema; Locks, Arno; Correa, Marcio; Correa, Letícia Ruhland

    2013-05-01

    The purposes of this study were to analyze and compare the immediate effects of rapid and slow maxillary expansion protocols, accomplished by Haas-type palatal expanders activated in different frequencies of activation on the positioning of the maxillary first permanent molars and on the buccal alveolar bones of these teeth with cone-beam computerized tomography. The sample consisted of 33 children (18 girls, 15 boys; mean age, 9 years) randomly distributed into 2 groups: rapid maxillary expansion (n = 17) and slow maxillary expansion (n = 16). Patients in the rapid maxillary expansion group received 2 turns of activation (0.4 mm) per day, and those in the slow maxillary expansion group received 2 turns of activation (0.4 mm) per week until 8 mm of expansion was achieved in both groups. Cone-beam computerized tomography images were taken before treatment and after stabilization of the jackscrews. Data were gathered through a standardized analysis of cone-beam computerized tomography images. Intragroup statistical analysis was accomplished with the Wilcoxon matched-pairs test, and intergroup statistical analysis was accomplished with analysis of variance. Linear relationships, among all variables, were determined by Spearman correlation. Both protocols caused buccal displacement of the maxillary first permanent molars, which had more bodily displacement in the slow maxillary expansion group, whereas more inclination was observed in the rapid maxillary expansion group. Vertical and horizontal bone losses were found in both groups; however, the slow maxillary expansion group had major bone loss. Periodontal modifications in both groups should be carefully considered because of the reduction of spatial resolution in the cone-beam computerized tomography examinations after stabilization of the jackscrews. Modifications in the frequency of activation of the palatal expander might influence the dental and periodontal effects of palatal expansion. Copyright © 2013

  3. Effect of a low-level laser on bone regeneration after rapid maxillary expansion.

    Science.gov (United States)

    Cepera, Fernanda; Torres, Fernando C; Scanavini, Marco A; Paranhos, Luiz R; Capelozza Filho, Leopoldino; Cardoso, Mauricio A; Siqueira, Danieli C R; Siqueira, Danilo F

    2012-04-01

    In this study, we evaluated the effects of a low-level laser on bone regeneration in rapid maxillary expansion procedures. Twenty-seven children, aged 8 to 12 years, took part in the experiment, with a mean age of 10.2 years, divided into 2 groups: the laser group (n = 14), in which rapid maxillary expansion was performed in conjunction with laser use, and the no-laser group (n = 13), with rapid maxillary expansion only. The activation protocol of the expansion screw was 1 full turn on the first day and a half turn daily until achieving overcorrection. The laser type used was a laser diode (TWIN Laser; MMOptics, São Carlos, Brazil), according to the following protocol: 780 nm wavelength, 40 mW power, and 10 J/cm(2) density at 10 points located around the midpalatal suture. The application stages were 1 (days 1-5 of activation), 2 (at screw locking, on 3 consecutive days), 3, 4, and 5 (7, 14, and 21 days after stage 2). Occlusal radiographs of the maxilla were taken with the aid of an aluminum scale ruler as a densitometry reference at different times: T1 (initial), T2 (day of locking), T3 (3-5 days after T2), T4 (30 days after T3), and T5 (60 days after T4). The radiographs were digitized and submitted to imaging software (Image Tool; UTHSCSA, San Antonio, Tex) to measure the optic density of the previously selected areas. To perform the statistical test, analysis of covariance was used, with the time for the evaluated stage as the covariable. In all tests, a significance level of 5% (P maxillary expansion, provided efficient opening of the midpalatal suture and influenced the bone regeneration process of the suture, accelerating healing. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  4. [The effect of two different methods of rapid maxillary expansion on treatment results of skeletal Class III malocclusion patients with maxillary protraction in early permanent dentition].

    Science.gov (United States)

    Chen, Xi-hua; Xie, Xing-qian

    2012-10-01

    To evaluate and compare the effect of single rapid maxillary expansion and repetitive rapid expansion and constriction with maxillary protraction in treating early permanent skeletal Class III patients. Twenty children with skeletal Class III malocclusion were randomly divided into two groups.Ten patients received 1 week of rapid expansion,followed by maxillary protraction(group A) and the other ten patients received 5 weeks of repetitive rapid expansion and constriction followed by maxillary protraction (group B).Cephalometric analysis was performed before and after treatment. The data was analyzed with SPSS 13.0 software package for paired t test. Significant changes in cranio-maxillofacial structures were observed in both groups after 6 months of treatment.Point A moved forward. SNA, ANB, UL-EP, U1-PP, SN-MP, ANS-Me/N-Me, Wit's value increased. L1-MP, LL-EP decreased. Significant differences were found in SNA,ANB,UL-EP between the two groups(PClass III malocclusion patients.

  5. Model of oronasal rehabilitation in children with obstructive sleep apnea syndrome undergoing rapid maxillary expansion: Research review

    OpenAIRE

    Levrini, Luca; Lorusso, Paola; Caprioglio, Alberto; Magnani, Augusta; Diaféria, Giovana; Bittencourt, Lia; Bommarito, Silvana

    2014-01-01

    Rapid maxillary expansion (RME) is a widely used practice in orthodontics. Scientific evidence shows that RME can be helpful in modifying the breathing pattern in mouth-breathing patients. In order to promote the restoration of physiological breathing we have developed a rehabilitation program associated with RME in children. The aim of the study was a literature review and a model of orofacial rehabilitation in children with obstructive sleep apnea undergoing treatment with rapid maxillary e...

  6. An assessment of the maxilla after rapid maxillary expansion using cone beam computed tomography in growing children.

    Science.gov (United States)

    Woller, Jessica L; Kim, Ki Beom; Behrents, Rolf G; Buschang, Peter H

    2014-01-01

    With the advent of cone beam computed tomography (CBCT), it is now possible to quantitatively evaluate the effects of rapid maxillary expansion (RME) on the entire maxillary complex in growing patients. The purpose of this study is to use three-dimensional images to evaluate the displacement that occurs at the circummaxillary sutures (frontonasal, zygomaticomaxillary, intermaxillary, midpalatal, and transpalatal sutures) following rapid maxillary expansion in growing children. The CBCT scans of 25 consecutively treated RME patients (10 male, 15 female) with mean age of 12.3±2.6 years, were examined before expansion and immediately following the last activation of the expansion appliance. Statistically significant (Pmaxillary first molars due to RME was also statistically significant. There was no statistically significant displacement of the transpalatal suture. Rapid maxillary expansion results in significant displacement of the bones of circummaxillary sutures in growing children.

  7. A-4-4.Asymmetrical rapid maxillary expansionとcorticotomyを併用した成人下顎前突症の1例

    National Research Council Canada - National Science Library

    福山英治; 大村進; 河原日登美; 関洋一郎; 齋藤友克; 海野智; 藤田浄秀; 相馬邦道

    2003-01-01

    Surgically assisted rapid maxillary expansionはLe fort I型に準じた骨切りに正中口蓋部の骨切りを加え左右のsegmentをほぼ対称的に拡大することが一般的な術式となっている. 今回われわれは, 上顎狭窄をともなう成人下顎前突症患者に対して, 片側Le fort I型骨切りと同側の口蓋骨切りを加え片側のみを拡大するAsymmetrical rapid maxillary expansion...

  8. Morphologic changes of the palate after rapid maxillary expansion: a 3-dimensional computed tomography evaluation.

    Science.gov (United States)

    Phatouros, Andriana; Goonewardene, Mithran S

    2008-07-01

    The purpose of this retrospective study was to estimate the area change of the palate after rapid maxillary expansion (RME) in the early mixed dentition stage by using a 3-dimensional (3D) helical computed tomography (CT) scanning technique. In addition, linear changes in the maxillary arch were evaluated. The treated sample consisted of 43 children (mean age, 9 years 1 month) treated with a bonded RME appliance. The untreated control group consisted of 7 children (mean age, 9 years 3 months). Pretreatment and posttreatment dental casts were evaluated by using 3D helical CT scanning procedures. The Student t test was used to compare the linear, area, and angular differences between the treatment times. RME produced clinically significant increases in interdental widths across the canines, the deciduous first molars, and the permanent first molars in the maxillary arch. Significant increases in cross-sectional area were observed across the permanent first molars (15.3 mm(2)). There was marked variability in the buccal tipping of the permanent first molars. Three-dimensional helical CT scanning is an accurate and cost-effective method of assessing dental cast morphologic changes. It can also provide fast and accurate data acquisition and subsequent analysis.

  9. Rapid Maxillary Expansion Increases Internal Nasal Dimensions of Children With Bilateral Cleft Lip and Palate.

    Science.gov (United States)

    Trindade-Suedam, Ivy Kiemle; Castilho, Ricardo Leão; Sampaio-Teixeira, Ana Claudia Martins; Araújo, Bruna Mara Adorno Marmotel; Fukushiro, Ana Paula; Campos, Letícia Dominguez; Trindade, Inge Elly Kiemle

    2016-05-01

    The transverse maxillary deficiency frequently observed in patients with cleft lip and palate (CLP) is usually treated by rapid maxillary expansion (RME). Considering that RME causes a significant increase of the internal nasal dimensions in children with unilateral CLP (UCLP), this study aimed to characterize the internal nasal geometry of children with bilateral CLP (BCLP) and transverse maxillary deficiency using acoustic rhinometry. The study also aimed to analyze changes caused by RME. Cross-sectional prospective study. Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil. Fifteen children with repaired BCLP of both genders, aged 8 to 15 years, referred for RME, were prospectively analyzed. Subjects underwent acoustic rhinometry before the expander installation and after the active phase of expansion. Cross-sectional areas (CSA) and volumes (V) of the nasal valve regions (CSA1 and V1) and turbinates (CSA2, CSA3, and V2), were measured after nasal decongestion. In the majority of the subjects, an increase of internal nasal dimensions was observed. Percent changes of CSA1, CSA2, CSA3, V1, and V2 were: +25%, +11%, +9%, 20%, and +12%, respectively. Differences were significant for all variables studied, except CSA3 (P < .05). RME promotes an increase in the internal nasal dimensions of children with BCLP, suggesting that RME is capable of substantially improving nasal patency in this population.

  10. Immediate impact of rapid maxillary expansion on upper airway dimensions and on the quality of life of mouth breathers

    Directory of Open Access Journals (Sweden)

    Edna Namiko Izuka

    2015-06-01

    Full Text Available OBJECTIVE: To assess short-term tomographic changes in the upper airway dimensions and quality of life of mouth breathers after rapid maxillary expansion (RME. METHODS: A total of 25 mouth breathers with maxillary atresia and a mean age of 10.5 years old were assessed by means of cone-beam computed tomography (CBCT and a standardized quality of life questionnaire answered by patients' parents/legal guardians before and immediately after rapid maxillary expansion. RESULTS: Rapid maxillary expansion resulted in similar and significant expansion in the width of anterior (2.8 mm, p < 0.001 and posterior nasal floor (2.8 mm, p < 0.001. Although nasopharynx and nasal cavities airway volumes significantly increased (+1646.1 mm3, p < 0.001, oropharynx volume increase was not statistically significant (+1450.6 mm3, p = 0.066. The results of the quality of life questionnaire indicated that soon after rapid maxillary expansion, patients' respiratory symptoms significantly decreased in relation to their initial respiratory conditions. CONCLUSIONS: It is suggested that RME produces significant dimensional increase in the nasal cavity and nasopharynx. Additionally, it also positively impacts the quality of life of mouth-breathing patients with maxillary atresia.

  11. Rapid maxillary expansion (RME) for pediatric obstructive sleep apnea: a 12-year follow-up.

    Science.gov (United States)

    Pirelli, Paola; Saponara, Maurizio; Guilleminault, Christian

    2015-08-01

    The objective of this study was to prospectively evaluate the long-term efficacy of rapid maxillary expansion (RME) in a group of children with obstructive sleep apnea (OSA). Thirty-one children diagnosed with OSA were involved in the study. These children had isolated maxillary narrowing and absence of enlarged adenotonsils at baseline. Twenty-three individuals (73% of the initial group) were followed up annually over a mean of 12 years after the completion of orthodontic treatment at a mean age of 8.68 years. Eight children dropped out over time due to either moving out of the area (n = 6) or refusal to submit to regular follow-up (n = 2). Subjects underwent clinical reevaluation over time and repeat polysomnography (PSG) in the late teenage years or in their early 20s. During the follow-up period, eight children dropped out and 23 individuals (including 10 girls) underwent a final clinical investigation with PSG (mean age of 20.9 years). The final evaluation also included computerized tomographic (CT) imaging that was compared with pre- and post-initial treatment findings. Yearly clinical evaluations, including orthodontic and otolaryngological examinations and questionnaire scores, were consistently normal over time, and PSG findings remained normal at the 12-year follow-up period. The stability and maintenance of the expansion over time was demonstrated by the maxillary base width and the distance of the pterygoid processes measured using CT imaging. A subgroup of OSA children with isolated maxillary narrowing initially and followed up into adulthood present stable, long-term results post RME treatment for pediatric OSA. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Slow versus rapid maxillary expansion in bilateral cleft lip and palate: a CBCT randomized clinical trial.

    Science.gov (United States)

    de Almeida, Araci Malagodi; Ozawa, Terumi Okada; Alves, Arthur César de Medeiros; Janson, Guilherme; Lauris, José Roberto Pereira; Ioshida, Marilia Sayako Yatabe; Garib, Daniela Gamba

    2017-06-01

    The purpose of this "two-arm parallel" trial was to compare the orthopedic, dental, and alveolar bone plate changes of slow (SME) and rapid (RME) maxillary expansions in patients with complete bilateral cleft lip and palate (BCLP). Forty-six patients with BCLP and maxillary arch constriction in the late mixed dentition were randomly and equally allocated into two groups. Computer-generated randomization was used. Allocation was concealed with sequentially, numbered, sealed, opaque envelopes. The SME and RME groups comprised patients treated with quad-helix and Haas/Hyrax-type expanders, respectively. Cone-beam computed tomography (CBCT) exams were performed before expansion and 4 to 6 months post-expansion. Nasal cavity width, maxillary width, alveolar crest width, arch width, palatal cleft width, inclination of posterior teeth, alveolar crest level, and buccal and lingual bone plate thickness were assessed. Blinding was applicable for outcome assessment only. Interphase and intergroup comparisons were performed using paired t tests and t tests, respectively (p Palatal cleft width had a significant increase in both groups. Significant buccal inclination of posterior teeth was only observed for RME. Additionally, both expansion procedures promoted a slight reduction of the alveolar crest level and the buccal bone plate thickness. No difference was found between the orthopedic, dental, and alveolar bone plate changes of SME and RME in children with BCLP. Both appliances produced significant skeletal transverse gains with negligible periodontal bone changes. Treatment time for SME, however, was longer than the observed for RME. SME and RME can be similarly indicated to correct maxillary arch constriction in patients with BCLP in the mixed dentition.

  13. Photographic assessment of nasal morphology following rapid maxillary expansion in children

    Directory of Open Access Journals (Sweden)

    Omar Gabriel da Silva Filho

    2011-10-01

    Full Text Available OBJECTIVE: The aim of the present study was to use facial analysis to determine the effects of rapid maxillary expansion (RME on nasal morphology in children in the stages of primary and mixed dentition, with posterior cross-bite. MATERIAL AND METHODS: Facial photographs (front view and profile of 60 patients in the pre-expansion period, immediate post-expansion period and one year following rapid maxillary expansion with a Haas appliance were evaluated on 2 occasions by 3 experienced orthodontists independently, with a 2-week interval between evaluations. The examiners were instructed to assess nasal morphology and had no knowledge regarding the content of the study. Intraexaminer and interexaminer agreement (assessed using the Kappa statistic was acceptable. RESULTS: From the analysis of the mode of the examiners' findings, no alterations in nasal morphology occurred regarding the following aspects: dorsum of nose, alar base, nasal width of middle third and nasal base. Alterations were only detected in the nasolabial angle in 1.64% of the patients between the pre-expansion and immediate post-expansion photographs. In 4.92% of the patients between the immediate post-expansion period and 1 year following expansion; and in 6.56% of the patients between the pre-expansion period and one year following expansion. CONCLUSIONS: RME performed on children in stages of primary and mixed dentition did not have any impact on nasal morphology, as assessed using facial analysis.

  14. Rapid maxillary expansion outcomes in treatment of obstructive sleep apnea in children.

    Science.gov (United States)

    Villa, Maria Pia; Rizzoli, Alessandra; Rabasco, Jole; Vitelli, Ottavio; Pietropaoli, Nicoletta; Cecili, Manuela; Marino, Alessandra; Malagola, Caterina

    2015-06-01

    The objectives of this study were to confirm the efficacy of rapid maxillary expansion in children with moderate adenotonsillar hypertrophy in a larger sample and to evaluate retrospectively its long-term benefits in a group of children who underwent orthodontic treatment 10 years ago. After general clinical examination and overnight polysomnography, all eligible children underwent cephalometric evaluation and started 12 months of therapy with rapid maxillary expansion. A new polysomnography was performed at the end of treatment (T1). Fourteen children underwent clinical evaluation and Brouilette questionnaire, 10 years after the end of treatment (T2). Forty patients were eligible for recruitment. At T1, 34/40 (85%) patients showed a decrease of apnea-hypopnea index (AHI) greater than 20% (ΔAHI 67.45% ± 25.73%) and were defined responders. Only 6/40 (15%) showed a decrease  1 ev/h) after treatment. Disease duration was significantly lower (2.5 ± 1.4 years vs 4.8 ± 1.9 years, p children (mean age 17.0 ± 1.9 years) who ended orthodontic treatment 10 years previously showed improvement of Brouilette score. Starting an orthodontic treatment as early as symptoms appear is important in order to increase the efficacy of treatment. An integrated therapy is needed. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Photographic assessment of nasal morphology following rapid maxillary expansion in children

    Science.gov (United States)

    da SILVA FILHO, Omar Gabriel; LARA, Tulio Silva; AYUB, Priscila Vaz; OHASHI, Amanda Sayuri Cardoso; BERTOZ, Francisco Antônio

    2011-01-01

    Objective The aim of the present study was to use facial analysis to determine the effects of rapid maxillary expansion (RME) on nasal morphology in children in the stages of primary and mixed dentition, with posterior cross-bite. Material and Methods Facial photographs (front view and profile) of 60 patients in the pre-expansion period, immediate post-expansion period and one year following rapid maxillary expansion with a Haas appliance were evaluated on 2 occasions by 3 experienced orthodontists independently, with a 2-week interval between evaluations. The examiners were instructed to assess nasal morphology and had no knowledge regarding the content of the study. Intraexaminer and interexaminer agreement (assessed using the Kappa statistic) was acceptable. Results From the analysis of the mode of the examiners' findings, no alterations in nasal morphology occurred regarding the following aspects: dorsum of nose, alar base, nasal width of middle third and nasal base. Alterations were only detected in the nasolabial angle in 1.64% of the patients between the pre-expansion and immediate post-expansion photographs. In 4.92% of the patients between the immediate post-expansion period and 1 year following expansion; and in 6.56% of the patients between the pre-expansion period and one year following expansion. Conclusion RME performed on children in stages of primary and mixed dentition did not have any impact on nasal morphology, as assessed using facial analysis. PMID:21986660

  16. Cone-beam computed tomography evaluation of dentoskeletal changes after asymmetric rapid maxillary expansion.

    Science.gov (United States)

    Baka, Zeliha Muge; Akin, Mehmet; Ucar, Faruk Izzet; Ileri, Zehra

    2015-01-01

    The aims of this study were to quantitatively evaluate the changes in arch widths and buccolingual inclinations of the posterior teeth after asymmetric rapid maxillary expansion (ARME) and to compare the measurements between the crossbite and the noncrossbite sides with cone-beam computed tomography (CBCT). From our clinic archives, we selected the CBCT records of 30 patients with unilateral skeletal crossbite (13 boys, 14.2 ± 1.3 years old; 17 girls, 13.8 ± 1.3 years old) who underwent ARME treatment. A modified acrylic bonded rapid maxillary expansion appliance including an occlusal locking mechanism was used in all patients. CBCT records had been taken before ARME treatment and after a 3-month retention period. Fourteen angular and 80 linear measurements were taken for the maxilla and the mandible. Frontally clipped CBCT images were used for the evaluation. Paired sample and independent sample t tests were used for statistical comparisons. Comparisons of the before-treatment and after-retention measurements showed that the arch widths and buccolingual inclinations of the posterior teeth increased significantly on the crossbite side of the maxilla and on the noncrossbite side of the mandible (P ARME treatment, the crossbite side of the maxilla and the noncrossbite side of the mandible were more affected than were the opposite sides. Copyright © 2015. Published by Elsevier Inc.

  17. Correction of a skeletal Class II malocclusion with severe crowding by a specially designed rapid maxillary expander.

    Science.gov (United States)

    Wang, Honghong; Feng, Jing; Lu, Peijun; Shen, Gang

    2015-02-01

    To correct an Angle Class II malocclusion or to create spaces in the maxillary arch by nonextraction treatment, distal movement of the maxillary molars is required. Various modalities for distalizing the buccal segment have been reported. Conventional extraoral appliances can be used to obtain maximum anchorage. However, many patients reject headgear wear because of social and esthetic concerns, and the success of this treatment depends on patient compliance. Intraoral appliances, such as repelling magnets, nickel-titanium coils, pendulum appliance, Jones jig appliance, distal jet appliance, and modified Nance appliance, have been introduced to distalize the molars with little or no patient cooperation. However, intraoral appliances can result in anchorage loss of the anterior teeth and distal tipping of the maxillary molars. In this case report, we introduce a diversified rapid maxillary expansion appliance that was custom designed and fabricated for the treatment of a growing girl with a skeletal Class II malocclusion and severe crowding from a totally lingually positioned lateral incisor. The appliance concomitantly expanded the maxilla transversely and retracted the buccal segment sagittally, distalizing the maxillary molars to reach a Class I relationship and creating the spaces to displace the malpositioned lateral incisor. The uniqueness of this special diversified rapid maxillary expansion appliance was highlighted by a series of reconstructions and modifications at different stages of the treatment to reinforce the anchorage. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  18. Displacements prediction from 3D finite element model of maxillary protraction with and without rapid maxillary expansion in a patient with unilateral cleft palate and alveolus.

    Science.gov (United States)

    Zhang, Dan; Zheng, Li; Wang, Qiang; Lu, Li; Ma, Jia

    2015-08-19

    Both maxillary protraction and rapid expansion are recommended for patients with cleft palate and alveolus. The aim of the study is to establish a three-dimensional finite element model of the craniomaxillary complex with unilateral cleft palate and alveolus to simulate maxillary protraction with and without rapid maxillary expansion. The study also investigates the deformation of the craniomaxillary complex after applied orthopaedic forces in different directions. A three dimensional finite element model of 1,277,568 hexahedral elements (C3D8) and 1,801,945 nodes was established based upon CT scan of a patient with unilateral cleft palate and alveolus on the right side in this study. A force of 4.9 N per side was directed on the anatomic height of contour on the buccal side of the first molar. The angles between the force vector and occlusal plane were -30°, -20°, -10°, 0°, 10°, 20°, and 30°. A force of 2.45 N on each loading point was directed on the anatomic height of contour on the lingual side of the first premolar and the first molar to simulate the expansion of the palate. The craniomaxillary complex displaced forward under any of the loading conditions. The sagittal and vertical displacement of the craniomaxillary complex reached their peak at the protraction degree of -10° forward and downward to the occlusal plane. There were larger sagittal displacements when the maxilla was protracted forward with maxillary expansion. The palatal plane rotated counterclockwise under any of the loading conditions. Being protracted without expansion, the dental arch was constricted. When supplemented with maxillary expansion, the width of the dental arch increased. Transverse deformation of the dental arch on affected side was different from that on unaffected side. Protraction force alone led the craniomaxillary complex moved forward and counterclockwise, accompanied with lateral constrain on the dental arch. Additional rapid maxillary expansion resulted in a

  19. Effect of a rapid maxillary expansion on snoring and sleep in children: a pilot study.

    Science.gov (United States)

    Giannasi, Lilian Chrystiane; Santos, Israel Reis; Alfaya, Thays Almeida; Bussadori, Sandra Kalil; Leitão-Filho, Fernando Studart; de Oliveira, Luis Vicente Franco

    2015-07-01

    The aim of this study was to assess the efficacy of the McNamara rapid palatal expansion device for the treatment of sleep disorders in children. The sample enrolled 12 children aged 4-11 years. Children with snoring and bruxism whose parents did not agree to tonsil surgery were included in the study. During the initial evaluation, a questionnaire addressing sleep was administered, and plaster models were made for the construction of the McNamara rapid maxillary expansion device. The expansion period was 7-15 days, and the McNamara device was removed after 6-8 months. The same questionnaire was administered again after 30 days of use of the orthopedic appliance. The data were analyzed using the McNemar test, with the level of significance set to 5% (Pmaxillary expansion, can be an effective treatment for snoring and other undesirable sleep behaviors in children.

  20. Asymmetric rapid maxillary expansion in true unilateral crossbite malocclusion: a prospective controlled clinical study.

    Science.gov (United States)

    Ileri, Zehra; Basciftci, Faruk Ayhan

    2015-03-01

    To investigate the short-term effects of the asymmetric rapid maxillary (ARME) appliance on the vertical, sagittal, and transverse planes in patients with true unilateral posterior crossbite. Subjects were divided into two groups. The treatment group was comprised of 21 patients with unilateral posterior crossbite (mean age  =  13.3 ± 2.1 years). Members of this group were treated with the ARME appliance. The control group was comprised of 17 patients with Angle Class I who were kept under observation (mean age  =  12.3 ± 0.8 years). Lateral and frontal cephalograms were taken before the expansion (T1), immediately after expansion (T2), and at postexpansion retention (T3) in the treatment group and at preobservation (T1) and postobservation (T2) in the control group. A total of 34 measurements were assessed on cephalograms. For statistical analysis, the Wilcoxon test and analysis of covariance were used. The ARME appliance produced significant increases in nasal, maxillary base, upper arch, and lower arch dimensions (P ARME appliance created asymmetric increments in the transversal dimensions of the nose, maxilla, and upper arch in the short term. Asymmetric expansion therapy for subjects with unilateral maxillary deficiency may provide satisfactory outcomes in adolescents, with the exception of mandibular arch expansion. The triangular pattern of expansion caused clockwise rotation of the mandible and the occlusal plane and produced significant alterations in the vertical facial dimensions, whereas it created no displacement in maxilla in the sagittal plane.

  1. An assessment of the maxilla after rapid maxillary expansion using cone beam computed tomography in growing children

    Directory of Open Access Journals (Sweden)

    Jessica L. Woller

    2014-01-01

    Full Text Available INTRODUCTION: With the advent of cone beam computed tomography (CBCT, it is now possible to quantitatively evaluate the effects of rapid maxillary expansion (RME on the entire maxillary complex in growing patients. OBJECTIVE: The purpose of this study is to use three-dimensional images to evaluate the displacement that occurs at the circummaxillary sutures (frontonasal, zygomaticomaxillary, intermaxillary, midpalatal, and transpalatal sutures following rapid maxillary expansion in growing children. METHODS: The CBCT scans of 25 consecutively treated RME patients (10 male, 15 female with mean age of 12.3 ± 2.6 years, were examined before expansion and immediately following the last activation of the expansion appliance. RESULTS: Statistically significant (P < 0.05 amounts of separation were found for the displacement of the bones of the frontonasal suture, the intermaxillary suture, the zygomaticomaxillary sutures, and the midpalatal suture. The change in angulation of the maxillary first molars due to RME was also statistically significant. There was no statistically significant displacement of the transpalatal suture. CONCLUSIONS: Rapid maxillary expansion results in significant displacement of the bones of circummaxillary sutures in growing children.

  2. Rapid maxillary expansion in the primary and mixed dentitions: a cephalometric evaluation.

    Science.gov (United States)

    da Silva Filho, O G; Boas, M C; Capelozza Filho, L

    1991-08-01

    The present study evaluated the skeletal alterations induced by rapid maxillary expansion procedures in 30 patients in the primary and mixed dentitions. The results were obtained with the use of lateral cephalometrics before and immediately after the active phase of expansion. The time span between these two cephalometric films ranged from 14 to 21 days; therefore the "growth factor" was not considered. Based on the differences in the cephalometric measurements studied on the first and second tracings, it seems that anterior displacement of the maxilla with significant changes in the SNA angle should not be expected, although point B was repositioned more posteriorly (SNB) because of the mandibular downward and backward rotation, with subsequent increase of the inclination of the mandibular plane. The alterations in the A-P position of the mandible was reflected in the increase of ANB and NAP angles. The maxilla always dislocates downward, displaying a downward and backward rotation in the palatine plane, significantly altering the following measurements: N-ANS, PNS-PNS', A-A', SN.PP. The anchoring molars also follow the downward maxillary displacement (M-M') and, as a direct consequence of the vertical displacement of the maxilla and upper molars (N-ANS, A-A', ANS-Me, N-Me, PNS-PNS'), the facial heights increase.

  3. Rapid maxillary expansion in therapy-resistant enuretic children: An orthodontic perspective.

    Science.gov (United States)

    Bazargani, Farhan; Jönson-Ring, Ingrid; Nevéus, Tryggve

    2016-05-01

    To evaluate whether rapid maxillary expansion (RME) could reduce the frequency of nocturnal enuresis (NE) in children and whether a placebo effect could be ruled out. Thirty-four subjects, 29 boys and five girls with mean age of 10.7 ± 1.8 years suffering from primary NE, were recruited. All subjects were nonresponders to the first-line antienuretic treatment and therefore were classified as "therapy resistant." To rule out a placebo effect of the RME appliance, all children were first treated with a passive appliance for 4 weeks. Rhinomanometry (RM), acoustic rhinometry (AR), polysomnographic registration, and study casts were made at different time points. One child experienced severe discomfort from the RME appliance and immediately withdrew from the study. Following RME, the long-term cure rate after 1 year was 60%. The RM and AR measurements at baseline and directly after RME showed a significant increase in nasal volume and nasal airflow, and there was a statistically significant correlation between reduction in enuresis and increase in nasal volume. Six months postretention, a 100% relapse of the dental overexpansion could be noted. RME has a curative effect in some children with NE, which could be connected to the positive influence of RME on the sleep architecture. Normal transverse occlusion does not seem to be a contraindication for moderate maxillary expansion in attempts to cure NE in children.

  4. A bilinear elastic constitutive model applied for midpalatal suture behavior during rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Larissa Carvalho Trojan Serpe

    Full Text Available Introduction : This study aims to evaluate the influence of the biomechanical behavior of the midpalatal suture (MPS during the rapid maxillary expansion (RME when modeled by the Finite Element Method. Methods Four simulation alternatives are discussed and, for each analysis, the suture is considered as a functional unit with a different mechanical behavior: (i without MPS elements, (ii MPS with Young's modulus (E equal to 1 MPa, (ii MPS with E equal to 0.01 MPa and (iv MPS with bilinear elastic behavior. Results The stress analysis showed that, when MPS is not considered in the model, stress peaks are reduced in magnitude and their distribution is restricted to a smaller area when compared to the model with the inclusion of MPS (E=1 MPa. The increased suture stiffness also has a direct influence on MPS displacements after 30 expander activations. Conclusion The consideration of the MPS in RME computer models influences greatly the calculated displacements between the suture bone ends, even as the stress levels in maxillary structures. Furthermore, as proposed for the described model, the elastic bilinear behavior assigned to MPS allows coherent prediction of stresses and displacements results, being a good representation for this suture overall behavior.

  5. Changes in head posture after rapid maxillary expansion in patients with nasopharyngeal obstruction

    Directory of Open Access Journals (Sweden)

    Kjurchieva-Chuchkova G

    2016-09-01

    Full Text Available Introduction: Nasopharyngeal obstruction is an important etiologic factor in the development of an extreme vertical growth facial pattern, and insufficient transversal growth of the maxilla. The treatment outcomes associated with rapid maxillary expansion in the literature are mainly discussed in terms of changes in dentofacial morphology, without special reference to changes in the pharyngeal airway, the position of the mandible, hyoid bone and the tongue. Aim: The aim of this study was to evaluate the effects of rapid maxillary expansion (RME, on changes in head posture and airway dimension. Materials and methods: The cephalometric evaluation was conducted on thirty lateral cephalograms of patients with nasopharyngeal obstruction (mean age 9.11 years; standard deviation (SD ± 2.0; range 8-14 years treated with appliance for rapid maxillary expansion. Patients were randomly divided into two groups: 1 study group comprised of 15 patients treated with RME immediately after the first visit; 2 a control group comprised of 15 subjects monitored for approximately 12 months prior to commencing therapy, who became untreated controls. Lateral cephalograms, taken in the natural head position, were obtained at the first visit and 6 months later for all subjects. Six angular measurements were measured to describe craniocervical angulation, and five linear measurements were measured to describe airway dimension. Results: The investigated group treated with RME shows a statistically significant decrease in craniocervical angulation, especially at the angle of interaction between palatal plane and the tangent odontoid processus (4.07 degrees, for PP/OPT angle and angle interaction between palatal plane and the tangent of cervical vertebra (4.95 degrees for PP/CVT angle. Airway dimension in the treated group increased, especially at the levels PNS-ad1 (2.52 mm, ve-pve (2.97 mm, and uv-puv (2.88 mm. No significant changes were observed in the control group

  6. Cone-beam computed tomography evaluation of dental, skeletal, and alveolar bone changes associated with bonded rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Namrata Dogra

    2016-01-01

    Full Text Available Aims and Objectives: To evaluate skeletal changes in maxilla and its surrounding structures, changes in the maxillary dentition and maxillary alveolar bone changes produced by bonded rapid maxillary expansion (RME using cone-beam computed tomography (CBCT. Materials and Methods: The sample consisted of 10 patients (6 males and 4 females with age range 12 to 15 years treated with bonded RME. CBCT scans were performed at T1 (pretreatment and at T2 (immediately after expansion to evaluate the dental, skeletal, and alveolar bone changes. Results: RME treatment increased the overall skeletal parameters such as interorbital, zygomatic, nasal, and maxillary widths. Significant increases in buccal maxillary width was observed at first premolar, second premolar, and first molar level. There was a significant increase in arch width both on the palatal side and on the buccal side. Significant tipping of right and left maxillary first molars was seen. There were significant reductions in buccal bone plate thickness and increase in palatal bone plate thickness. Conclusions: Total expansion achieved with RME was a combination of dental, skeletal and alveolar bone changes. At the first molar level, 28.45% orthopedic, 16.03% alveolar bone bending, and 55.5% orthodontic changes were observed.

  7. Dental arch changes associated with rapid maxillary expansion: A retrospective model analysis study

    Directory of Open Access Journals (Sweden)

    Ivor M D′Souza

    2015-01-01

    Full Text Available Introduction: Transverse deficiency of the maxilla is a common clinical problem in orthodontics and dentofacial orthopedics. Transverse maxillary deficiency, isolated or associated with other dentofacial deformities, results in esthetic and functional impairment giving rise to several clinical manifestations such as asymmetrical facial growth, positional and functional mandibular deviations, altered dentofacial esthetics, adverse periodontal responses, unstable dental tipping, and other functional problems. Orthopedic maxillary expansion is the preferred treatment approach to increase the maxillary transverse dimension in young patients by splitting of the mid palatal suture. This orthopedic procedure has lately been subject of renewed interest in orthodontic treatment mechanics because of its potential for increasing arch perimeter to alleviate crowding in the maxillary arch without adversely affecting facial profile. Hence, the present investigation was conducted to establish a correlation between transverse expansion and changes in the arch perimeter, arch width and arch length. Methods: For this purpose, 10 subjects (five males, five females were selected who had been treated by rapid maxillary expansion (RME using hyrax rapid palatal expander followed by fixed mechanotherapy (PEA. Pretreatment (T1, postexpansion (T2, and posttreatment (T3 dental models were compared for dental changes brought about by RME treatment and its stability at the end of fixed mechanotherapy. After model measurements were made, the changes between T1-T2, T2-T3 and T1-T3 were determined for each patient. The mean difference between T1-T2, T2-T3 and T1-T3 were compared to assess the effects of RME on dental arch measurements. Results are expressed as mean ± standard deviation and are compared by repeated measures analysis of variance followed by a post-hoc test. Arch perimeter changes are correlated with changes in arch widths at the canine, premolar and molar

  8. Maxillary arch rehabilitation using implant-supported computer-assisted design-computer-assisted manufacturing-milled titanium framework

    Directory of Open Access Journals (Sweden)

    Tulika S Khanna

    2017-01-01

    Full Text Available Esthetic and functional rehabilitation of completely edentulous maxillary arch with fixed implant supported prosthesis is a challenging task. Newer technologies such as computer assisted design computer assisted manufacturing (CAD CAM and cone beam conventional tomography play an important role in achieving predictable results. Full mouth porcelain fused to metal (PFM individual crowns on CAD CAM milled titanium framework provides positive esthetic and functional outcome. This is a case report of rehabilitation of partially edentulous maxillary arch patient. Staged rehabilitation of this patient was planned. In the first stage, root canal treatment of key abutment teeth was done, nonsalvageable teeth were removed, and immediate interim overdenture was provided. In the second stage, five Nobel Biocare dental implants were placed. After integration impressions were made, CAD CAM milled titanium bar was fabricated. Individual PFM crowns were made and cemented. This method gives better esthetic compared to acrylic fused to metal hybrid prosthesis with the advantage of retrievability just like screw retained prosthesis. Hence, this technique is good for rehabilitation of patients with high esthetic demands.

  9. Rapid maxillary anterior teeth retraction en masse by bone compression: a canine model.

    Directory of Open Access Journals (Sweden)

    Chufeng Liu

    Full Text Available OBJECTIVE: The present study sought to establish an animal model to study the feasibility and safety of rapid retraction of maxillary anterior teeth en masse aided by alveolar surgery in order to reduce orthodontic treatment time. METHOD: Extraction of the maxillary canine and alveolar surgery were performed on twelve adult beagle dogs. After that, the custom-made tooth-borne distraction devices were placed on beagles' teeth. Nine of the dogs were applied compression at 0.5 mm/d for 12 days continuously. The other three received no force as the control group. The animals were killed in 1, 14, and 28 days after the end of the application of compression. RESULTS: The tissue responses were assessed by craniometric measurement as well as histological examination. Gross alterations were evident in the experimental group, characterized by anterior teeth crossbite. The average total movements of incisors within 12 days were 4.63±0.10 mm and the average anchorage losses were 1.25±0.12 mm. Considerable root resorption extending into the dentine could be observed 1 and 14 days after the compression. But after consolidation of 28 days, there were regenerated cementum on the dentine. There was no apparent change in the control group. No obvious tooth loosening, gingival necrosis, pulp degeneration, or other adverse complications appeared in any of the dogs. CONCLUSIONS: This is the first experimental study for testing the technique of rapid anterior teeth retraction en masse aided by modified alveolar surgery. Despite a preliminary animal model study, the current findings pave the way for the potential clinical application that can accelerate orthodontic tooth movement without many adverse complications. CLINICAL RELEVANCE: It may become a novel method to shorten the clinical orthodontic treatment time in the future.

  10. Rapid maxillary expansion and obstructive sleep apnea: A review and meta-analysis.

    Science.gov (United States)

    Machado-Júnior, A-J; Zancanella, E; Crespo, A-N

    2016-07-01

    OSAS during childhood leads to significant physical and neuropsychomotor impairment. Thus, it needs to be recognized and treated early in order to avoid or attenuate the chronic problems associated with OSAS, which are deleterious to a child's development. Adenotonsillectomy and, in select cases, continuous positive airwaypressure (CPAP) have been the preferred treatments for OSAS in children, and yet they are ineffective at fully ameliorating the disease. Minimally invasive treatments have recently been proposed, comprising intra-oral and extra-oral devices as well as speech therapy. Objetive: to conduct a meta-analysis on studies from around the world that used rapid maxillary expansion (RME) to treat OSAS in children. We performed a meta-analysis of studies using RME for OSA treatment in children. A literature survey was conductedusing PubMed and Medline for English articles published up to December 2014 with the following descriptors: SleepApnea, Obstructive, Children, Treatment, Orthodontic, Othopaedic, Maxillaryexpansion. Studies were included in the meta-analysisif they were case-controlled studies, randomized, and involved non-syndromic children aged 0 to 12years old diagnosed with OSA by the polysomnography apnea-hypopnea index (AHI) before and after the intervention, submitted RME only. In all, 10 articles conformed to the inclusion criteria and were included in this meta-analysis. The total sample size across all these articles was 215 children, having a mean age of 6.7 years,of whom58.6%were male. The mean AHI during the follow-up was -6.86 (p <0.0001). We concluded that rapid maxillary expansion (RME) in children with OSAS appears to be an effective treatment for this syndrome. Further randomized clinical studies are needed to determine the effectiveness of RME in adults.

  11. Determination of forces on a split palatal screw after rapid maxillary expansion.

    Science.gov (United States)

    García, Valentin Javier; López-Cancelos, Rubén; Riveiro, Antonio; Comesaña, Rafael; Ustrell I Torrent, Josep Maria; Kasem, Khaled; Badaoui, Aida; Manzanares-Céspedes, Mª Cristina; Carvalho-Lobato, Patricia

    2017-09-01

    Aim of this study was to develop a finite element model of the forces that patients with rapid maxillary expansion bear and to validate it by a mechanical test. Computer-aided design models of the metallic screw and polymeric splint were modelled and discretized. Two forces were generated and considered independently: F1 at the temporary molar (2.5 N) and F2 at the permanent molar (2.5 N). The results of the finite element analysis were used to define the strain values which the anterior and posterior arms of the rapid maxillary expansion appliance bore as a linear function of F1-F2 by calculating the strain-force coefficient δ ij . Two strain gauge rosettes were attached to an appliance which was placed in an XY motorized stage to reproduce the same forces used in the finite element analysis. Once the system was validated, the matrix was inverted to determine forces F1 and F2 that a group of 40 patients underwent (median age 8.33 years, standard deviation 1.86 years) for 75 days, using their strain values. The parents of the patients activated a quarter turn (0.20 mm) twice a day until 50% transversal overcorrection was achieved. Finite element analysis showed that the effects of the forces on stress at the location of the arms were notably different. There was a satisfactory correlation between finite element analysis predictions and in vitro values. Dissipation of F1 and F2 in patients was predicted to be 62.5 and 80%, respectively, after 75 days of retention. These results back the finite element analysis model for force prediction.

  12. The Effects of Maxillary Protraction with or without Rapid Maxillary Expansion and Age Factors in Treating Class III Malocclusion: A Meta-Analysis

    Science.gov (United States)

    Zhang, Wei; Qu, Hong-Chen; Yu, Mo; Zhang, Yang

    2015-01-01

    We conducted a comprehensive meta-analysis of 12 studies to examine whether maxillary protraction face mask associated with rapid maxillary expansion (FM/RME) could be an effective treatment for Class III malocclusion and to evaluate the effect of timing on treatment response. Patients with a maxillary deficiency who were treated with FM with or without RME were compared with those who had an untreated Class III malocclusion. In both treatment groups, forward displacement of the maxilla and skeletal changes were found to be statistically significant. In addition, posterior rotation of the mandible and increased facial height were more evident in the FM group compared with the control group. However, no significant differences were observed between the early treatment groups and late treatment groups. The results indicated that both FM/RME and FM therapy produced favorable skeletal changes for correcting anterior crossbite, and the curative time was not affected by the presence of deciduous teeth, early mixed dentition or late mixed dentition in the patient. PMID:26068221

  13. The Effects of Maxillary Protraction with or without Rapid Maxillary Expansion and Age Factors in Treating Class III Malocclusion: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    Full Text Available We conducted a comprehensive meta-analysis of 12 studies to examine whether maxillary protraction face mask associated with rapid maxillary expansion (FM/RME could be an effective treatment for Class III malocclusion and to evaluate the effect of timing on treatment response. Patients with a maxillary deficiency who were treated with FM with or without RME were compared with those who had an untreated Class III malocclusion. In both treatment groups, forward displacement of the maxilla and skeletal changes were found to be statistically significant. In addition, posterior rotation of the mandible and increased facial height were more evident in the FM group compared with the control group. However, no significant differences were observed between the early treatment groups and late treatment groups. The results indicated that both FM/RME and FM therapy produced favorable skeletal changes for correcting anterior crossbite, and the curative time was not affected by the presence of deciduous teeth, early mixed dentition or late mixed dentition in the patient.

  14. Rapid Maxillary Expansion After Alveolar Bone Grafting With rhBMP-2 in UCLP Evaluated by Means of CBCT

    NARCIS (Netherlands)

    Garib, D.; Miranda, F.; Sathler, R.; Kuijpers-Jagtman, A.M.; Aiello, C.A.

    2017-01-01

    OBJECTIVE: To demonstrate the feasibility of rapid maxillary expansion (RME) after alveolar bone grafting (ABG) in complete unilateral cleft lip, alveolus and palate (UCLP) without damage to the grafted area. SETTING: Hospital for Rehabilitation of Craniofacial Anomalies (HRAC), University of Sao

  15. Mandibular response after rapid maxillary expansion in class II growing patients: a pilot randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Roberta Lione

    2017-11-01

    Full Text Available Abstract Background The aim of this pilot randomized controlled trial (RCT was to evaluate the sagittal mandibular response induced by rapid maxillary expansion (RME therapy in mixed dentition patients with class II malocclusion, comparing the effects of bonded RME and banded RME with a matched untreated class II control group. Methods This RCT was designed in parallel with an allocation ratio of 1:1:1. The sample consisted of 30 children with a mean age of 8.1 ± 0.6 years who were randomly assigned to three groups: group 1 treated with bonded RME, group 2 treated with banded RME, and group 3 the untreated control group. All patients met the following inclusion criteria: early mixed dentition, class II molar relationship, transverse discrepancy ≥ 4 mm, overjet ≥ 5 mm, and prepubertal skeletal maturity stage (CS1–CS2. The expansion screw was activated one quarter of a turn per day (0.25 mm until overcorrection was reached. For each subject, lateral cephalograms and plaster casts were obtained before treatment (T1 and after 1 year (T2. A randomization list was created for the group assignment, with an allocation ratio of 1:1:1. The observer who performed all the measurements was blinded to group assignment. The study was single-blinded in regard to statistical analysis. Results RME was effective in the correction of maxillary deficiency. Class II patients treated with both types of RME showed no significant improvement of the anteroposterior relationship of the maxilla and the mandible at both skeletal and occlusal levels. The acrylic splint RME had significant effects on reducing the skeletal vertical dimension and the gonial angle. Conclusions The orthopedic expansion did not affect the sagittal relationship of class II patients treated in the early mixed dentition when compared with the untreated control group. Additional studies with a larger sample are warranted to elucidate individual variations in dento-skeletal mandibular

  16. Mandibular response after rapid maxillary expansion in class II growing patients: a pilot randomized controlled trial.

    Science.gov (United States)

    Lione, Roberta; Brunelli, Valerio; Franchi, Lorenzo; Pavoni, Chiara; Quiroga Souki, Bernardo; Cozza, Paola

    2017-11-06

    The aim of this pilot randomized controlled trial (RCT) was to evaluate the sagittal mandibular response induced by rapid maxillary expansion (RME) therapy in mixed dentition patients with class II malocclusion, comparing the effects of bonded RME and banded RME with a matched untreated class II control group. This RCT was designed in parallel with an allocation ratio of 1:1:1. The sample consisted of 30 children with a mean age of 8.1 ± 0.6 years who were randomly assigned to three groups: group 1 treated with bonded RME, group 2 treated with banded RME, and group 3 the untreated control group. All patients met the following inclusion criteria: early mixed dentition, class II molar relationship, transverse discrepancy ≥ 4 mm, overjet ≥ 5 mm, and prepubertal skeletal maturity stage (CS1-CS2). The expansion screw was activated one quarter of a turn per day (0.25 mm) until overcorrection was reached. For each subject, lateral cephalograms and plaster casts were obtained before treatment (T1) and after 1 year (T2). A randomization list was created for the group assignment, with an allocation ratio of 1:1:1. The observer who performed all the measurements was blinded to group assignment. The study was single-blinded in regard to statistical analysis. RME was effective in the correction of maxillary deficiency. Class II patients treated with both types of RME showed no significant improvement of the anteroposterior relationship of the maxilla and the mandible at both skeletal and occlusal levels. The acrylic splint RME had significant effects on reducing the skeletal vertical dimension and the gonial angle. The orthopedic expansion did not affect the sagittal relationship of class II patients treated in the early mixed dentition when compared with the untreated control group. Additional studies with a larger sample are warranted to elucidate individual variations in dento-skeletal mandibular response to the maxillary expansion protocol in class

  17. Evaluation of the rapid and slow maxillary expansion using cone-beam computed tomography: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Juliana da S. Pereira

    Full Text Available ABSTRACT OBJECTIVE: The aim of this randomized clinical trial was to evaluate the dental, dentoalveolar, and skeletal changes occurring right after the rapid maxillary expansion (RME and slow maxillary expansion (SME treatment using Haas-type expander. METHODS: All subjects performed cone-beam computed tomography (CBCT before installation of expanders (T1 and right after screw stabilization (T2. Patients who did not follow the research parameters were excluded. The final sample resulted in 21 patients in RME group (mean age of 8.43 years and 16 patients in SME group (mean age of 8.70 years. Based on the skewness and kurtosis statistics, the variables were judged to be normally distributed and paired t-test and student t-test were performed at significance level of 5%. RESULTS: Intermolar angle changed significantly due to treatment and RME showed greater buccal tipping than SME. RME showed significant changes in other four measurements due to treatment: maxilla moved forward and mandible showed backward rotation and, at transversal level both skeletal and dentoalveolar showed significant changes due to maxillary expansion. SME showed significant dentoalveolar changes due to maxillary expansion. CONCLUSIONS: Only intermolar angle showed significant difference between the two modalities of maxillary expansion with greater buccal tipping for RME. Also, RME produced skeletal maxillary expansion and SME did not. Both maxillary expansion modalities were efficient to promote transversal gain at dentoalveolar level. Sagittal and vertical measurements did not show differences between groups, but RME promoted a forward movement of the maxilla and backward rotation of the mandible.

  18. Transverse effects on the nasomaxillary complex one year after rapid maxillary expansion as the only intervention: A controlled study

    Directory of Open Access Journals (Sweden)

    Carolina da Luz Baratieri

    2014-10-01

    Full Text Available The aim of this study was to assess by means of cone-beam computed tomography (CBCT scans the transverse effects on the nasomaxillary complex in patients submitted to rapid maxillary expansion (RME using Haas expander in comparison to untreated individuals. This prospective controlled clinical study assessed 30 subjects (18 boys and 12 girls with mixed dentition and during pubertal growth. The treated group was submitted to RME with Haas expander, retention for six months and a six-month follow-up after removal. The control group matched the treated group in terms of age and sex distribution. CBCT scans were taken at treatment onset and one year after the expander was activated. Maxillary first molars (U6 width, right and left U6 angulation, maxillary alveolar width, maxillary basal width, palatal alveolar width, palatal base width, right and left alveolar angulation, palatal area, nasal base width, nasal cavity width and inferior nasal cavity area on the posterior, middle and anterior coronal slices were measured with Dolphin Imaging Software(r 11.5, except for the first two variables which were performed only on the posterior slice. All transverse dimensions increased significantly (P 0.05. Results suggest that increase of molar, maxillary, palatal and nasal transverse dimensions was stable in comparison to the control group one year after treatment with RME.

  19. IBO Case Report: Management of Skeletal Class III Malocclusion with Combined Rapid Maxillary Expansion: Facemask Therapy and 5-Year Follow-up

    Directory of Open Access Journals (Sweden)

    Ashok Surana

    2012-01-01

    Full Text Available This case report describes the management of skeletal Class III malocclusion with maxillary deficiency in an adolescent girl, using combined rapid maxillary expansion-facemask approach, followed by comprehensive fixed appliance mechanotherapy. Excellent long-term stability is demonstrated up to 5 years post-treatment.

  20. Influence of Orthodontic Rapid Maxillary Expansion on Nocturnal Enuresis in Children.

    Science.gov (United States)

    Hyla-Klekot, Lidia; Truszel, Marek; Paradysz, Andrzej; Postek-Stefańska, Lidia; Życzkowski, Marcin

    2015-01-01

    The etiology of nocturnal enuresis (NE) is multifactorial and has not been fully explained yet. New ways of treatment are constantly being investigated, including the rapid maxillary expansion (RME). A total of 41 patients diagnosed with NE were divided into two experimental groups: A and B. Group A included 16 children who have been treated with RME. Group B comprised 25 children who have not undertaken orthodontic treatment. Children from both groups have been monitored in monthly intervals, during a 12-month period, towards the intensification of NE. The comparative analysis of both groups has been conducted after 3 years of observation. Statistical analysis has shown a 4.5 times increase of the probability of reduction of NE in the case of the treated group in comparison with the group of children who have not undergone orthodontic treatment. Unfortunately, the chance of obtaining total dryness diminished proportionally to the higher degree of intensification of enuresis at the beginning of the test. RME can constitute an alternative method of NE treatment in children, irrespective of the occurrence of upper jaw narrowing.

  1. Influence of Orthodontic Rapid Maxillary Expansion on Nocturnal Enuresis in Children

    Directory of Open Access Journals (Sweden)

    Lidia Hyla-Klekot

    2015-01-01

    Full Text Available Background. The etiology of nocturnal enuresis (NE is multifactorial and has not been fully explained yet. New ways of treatment are constantly being investigated, including the rapid maxillary expansion (RME. Methods. A total of 41 patients diagnosed with NE were divided into two experimental groups: A and B. Group A included 16 children who have been treated with RME. Group B comprised 25 children who have not undertaken orthodontic treatment. Children from both groups have been monitored in monthly intervals, during a 12-month period, towards the intensification of NE. The comparative analysis of both groups has been conducted after 3 years of observation. Results. Statistical analysis has shown a 4.5 times increase of the probability of reduction of NE in the case of the treated group in comparison with the group of children who have not undergone orthodontic treatment. Unfortunately, the chance of obtaining total dryness diminished proportionally to the higher degree of intensification of enuresis at the beginning of the test. Conclusion. RME can constitute an alternative method of NE treatment in children, irrespective of the occurrence of upper jaw narrowing.

  2. Effects of rapid maxillary expansion on head posture, postural stability, and fall risk

    Directory of Open Access Journals (Sweden)

    Fatih Celebi

    2017-01-01

    Full Text Available Objective: The aim of this study was to investigate the effects of rapid maxillary expansion (RME on head posture, postural stability, and fall risk. Materials and Methods: A sample of 51 adolescent patients was randomly divided into two groups. In the first group, which consisted of 28 patients (15 females and 13 males, RME was performed as a part of routine orthodontic treatment. The remaining 23 individuals (12 females and 11 males served as the control group. Lateral cephalometric radiographs taken in natural head position, postural stability, and fall risk scores were obtained during the first visit. They were repeated on average 3.8 months and 3.5 months later for the study and control groups, respectively. The changes were analyzed using the Wilcoxon signed-rank test, paired samples t-test, Mann–Whitney U-test, and independent samples t-test. Results: As a result of RME, a statistically significant decrease was detected in the fall risk score (P < 0.05 in the study group, while the head position and postural stability remained unchanged. For the control group, no significant changes were observed in all measurements. Conclusions: The result of the present study suggests that RME has a capacity of improving fall risk.

  3. [Effect of maxillary protraction with or without rapid palatal expansion in treating early skeletal Class III malocclusion].

    Science.gov (United States)

    Ma, Wen-Sheng; Lu, Hai-Yan; Dong, Fu-Sheng; Hu, Xiao-Ying; Li, Xing-Chao

    2009-04-01

    To evaluate the effectiveness of treatment with maxillary protraction with or without rapid palatal expansion (RPE) for skeletal Class III malocclusion in mixed dentition. A total of 31 children with Class III malocclusion in mixed dentition were selected, and 15 (group A) received maxillary protraction treatment with RPE, the other 16 (group B) received maxillary protraction without RPE. Cephalometric films were taken before and after treatment, and traditional and Pancherz analysis were used. The average duration of treatment was 10.14 months in group A and 9.77 months in group B respectively (P>0.05). According to Pancherz analysis, maxillary basal bone moved forwards by 2.99 mm in group A and 3.33 mm in group B respectively (P>0.05), mandibular basal bone moved backwards by 0.07 mm in group A, while forwards by 0.80 mm in group B (P>0.05), the overjet increased by 4.51 mm in group A and 6.37 mm in group B respectively (P0.05). The effects were clinically satisfactory in the both groups. Lower molar moved forwards by 1.18 mm in basal bone in group A, while backwards by 1.20 mm in group B (PClass III malocclusion.

  4. Rapid maxillary expansion versus middle ear tube placement: Comparison of hearing improvements in children with resistance otitis media with effusion.

    Science.gov (United States)

    Kılıç, Nihat; Yörük, Özgür; Kılıç, Songül Cömert; Çatal, Gülhan; Kurt, Sezgin

    2016-09-01

    To test the null hypothesis that there are significant differences in hearing improvements of children with resistance otitis media with effusion (OME) who undergo a rapid maxillary expansion (RME) procedure or ventilation tube placement. Forty-two children between 4.5 and 15 years old were divided into three groups: RME, ventilation tube, and control groups. The RME group consisted of 15 children with maxillary constriction and resistance OME that indicated ventilation tube placement. The ventilation tube group consisted of 16 children for whom ventilation tube placement was indicated but no maxillary constriction. The control group consisted of 11 children with no orthodontic and/or rhinologic problems. Hearing thresholds were evaluated with three audiometric records: (1) before RME/ventilation tube placement (T0); (2) after RME/ventilation tube placement (T1), and (3) after an observation period of 10 months (T2). The control group was matched to these periods, except T1. Hearing thresholds decreased significantly in both the RME and ventilation tube groups (P .05). Slight changes were observed in the control groups. The null hypothesis was rejected. RME showed similar effects as ventilation tube placement for release of otitis media and improvement of hearing thresholds levels. RME should be preferred as a first treatment option for children with maxillary constriction and resistance OME.

  5. Effect of maxillary protraction with alternating rapid palatal expansion and constriction vs expansion alone in maxillary retrusive patients: a single-center, randomized controlled trial.

    Science.gov (United States)

    Liu, Weitao; Zhou, Yanheng; Wang, Xuedong; Liu, Dawei; Zhou, Shaonan

    2015-10-01

    The objective of this randomized controlled trial was to investigate the effects of facemask protraction combined with alternating rapid palatal expansion and constriction (RPE/C) vs rapid palatal expansion (RPE) alone in the early treatment of maxillary retrusive patients. Patients with a midface deficiency were recruited and randomly allocated into either the control group (RPE) or the intervention group (RPE/C). Eligibility criteria included the following: age 7 to 13 years old, Class III malocclusion, anterior crossbite, ANB less than 0°, Wits appraisal less than -2 mm, A-Np less than 0 mm, and no cleft of lip or palate. The primary outcome was the degree of maxillary forward movement after treatment. The secondary outcomes were the changes of the other cephalometric variables after treatment and the treatment time. Simple randomization was carried out using a random number table at the beginning of the study. Envelopes containing the grouping information were used to ensure allocation concealment from the researchers. Blinding was applicable for cephalometric analysis only. Hyrax palatal expanders and facemask maxillary protraction were used in all patients. Patients in the RPE group were treated with rapid palatal expansion for 1 week. Patients in the RPE/C group were treated with RPE/C for 7 weeks. The expansion or constriction rate was 1 mm per day. Cephalometric analysis with traditional cephalometric measurements and an x-y coordinate system were used to compare the pretreatment and posttreatment cephalometric radiographs. Independent t tests were used to compare the data between the 2 groups. A total of 44 patients were randomized to either the RPE group or the RPE/C group in a 1:1 ratio. One subject in the RPE group was lost to follow-up during the treatment. Per-protocol analysis was used. All the other 43 patients reached the treatment completion criteria and were analyzed (RPE group: n = 21; RPE/C group: n = 22). The average protraction time was 10

  6. Effect of low-level laser therapy after rapid maxillary expansion: a clinical investigation.

    Science.gov (United States)

    Garcia, Valentin Javier; Arnabat, J; Comesaña, Rafael; Kasem, Khaled; Ustrell, Josep Maria; Pasetto, Stefano; Segura, Oscar Pozuelo; ManzanaresCéspedes, Maria Cristina; Carvalho-Lobato, Patricia

    2016-08-01

    To evaluate the effectiveness low-level laser therapy (LLLT) on the repair of the mid palatal suture, after rapid maxillary expansion (RME). A single-operator, randomized single-blind placebo-controlled study was performed at the Orthodontic Department at the Dental Hospital of Bellvitge. Barcelona University, Hospitalet de Llobregat, Spain. Thirty-nine children (range 6-12 years old), completed RME and were randomized to receive active LLLT (n = 20) or placebo (n = 19). The laser parameters and dose were 660 nm, 100 mW, CW, InGaAlP laser, illuminated area 0.26 cm(2), 332 mW/cm(2), 60 s to four points along midpalatal suture, and 30 s to a point each side of the suture. A total of seven applications were made on days 1, 7, 14, 28, 42, 56, and 70 of the retention phase RME. A cone beam computed tomography (CBCT) scan was carried out on the day of the first laser treatment, and at day 75, a second CBCT scan was performed. Two radiologists synchronized the slices of two scans to be assessed. P = 0.05 was considered to be statistically significant. At day 75 of the suture, the irradiated patients presented a greater percentage of approximate zones in the anterior (p = 0.008) and posterior (p = 0.001) superior suture-and less approximation in the posterior superior suture (p = 0.040)-than the placebo group. LLLT appears to stimulate the repair process during retention phase after RME.

  7. Rapid maxillary expansion in children with Obstructive Sleep Apnoea Syndrome (OSAS).

    Science.gov (United States)

    Marino, A; Ranieri, R; Chiarotti, F; Villa, M P; Malagola, C

    2012-03-01

    to evaluate the effects of rapid maxillary expansion (RME) in a group of OSAS preschool children. Lateral cephalograms of 15 OSAS children (8 boys and 7 girls, age mean ± SD: 5.94 ± 1.64 years) were analysed at the start of treatment with RME (T0). All subjects were revaluated after a mean period of 1.57 ± 0.58 years (T1). At this time the sample was divided into 2 groups according to the change in the respiratory disturbance index (RDI): an improved group (I: 8 subjects) and a stationary/worsened group (SW: 7 subjects). Differences between I and SW children with respect to values of cephalometric variables at T0 and to variations between T0 and T1 were evaluated using Mann-Whitney U test. Differences between T0 and T1 values in the overall group of children and separately in I and SW groups were assessed using Wilcoxon test. At the start of treatment, the I group was characterised by more retrognathic jaws with lower values of SNA (p=0.055) and SNB (p=0.020) and higher age values (p=0.093) when compared to SW group. After treatment, the I group showed an increase in SNA and SNB angle significantly higher than SW group (p=0.004 and p=0.003, respectively). On the contrary, I and SW groups did not differ as for variation in the skeletal divergency and in the total facial height. OSAS preschool children with retrognathic jaws could benefit from RME treatment.

  8. Volumetric upper airway changes after rapid maxillary expansion: a systematic review and meta-analysis.

    Science.gov (United States)

    Buck, Lloyd M; Dalci, Oyku; Darendeliler, M Ali; Papageorgiou, Spyridon N; Papadopoulou, Alexandra K

    2017-10-01

    Although Rapid Maxillary Expansion (RME) has been used for over a century, its effect on upper airways has not yet adequately been assessed in an evidence-based manner. To investigate the volumetric changes in the upper airway spaces following RME in growing subjects by means of acoustic rhinometry, three-dimensional radiography and digital photogrammetry. Literature search of electronic databases and additional manual searches up to February 2016. Randomized clinical trials, prospective or retrospective controlled clinical trials and cohort clinical studies of at least eight patients, where the RME appliance was left in place for retention, and a maximum follow-up of 8 months post-expansion. After duplicate data extraction and assessment of the risk of bias, the mean differences and 95 per cent confidence intervals (CIs) of upper airway volume changes were calculated with random-effects meta-analyses, followed by subgroup analyses, meta-regressions, and sensitivity analyses. Twenty studies were eligible for qualitative synthesis, of which 17 (3 controlled clinical studies and 14 cohort studies) were used in quantitative analysis. As far as total airway volume is concerned patients treated with RME showed a significant increase post-expansion (5 studies; increase from baseline: 1218.3mm3; 95 per cent CI: 702.0 to 1734.6mm3), which did not seem to considerably diminish after the retention period (11 studies; increase from baseline: 1143.9mm3; 95 per cent CI: 696.9 to 1590.9mm3). However, the overall quality of evidence was judged as very low, due to methodological limitations of the included studies, absence of untreated control groups, and inconsistency among studies. RME seems to be associated with an increase in the nasal cavity volume in the short and in the long term. However, additional well-conducted prospective controlled clinical studies are needed to confirm the present findings. None. Australian Society of Orthodontics Foundation for Research and

  9. Stress and displacement patterns in the craniofacial skeleton with rapid maxillary expansion-a finite element method study.

    Science.gov (United States)

    Priyadarshini, J; Mahesh, C M; Chandrashekar, B S; Sundara, Abhishek; Arun, A V; Reddy, Vinay P

    2017-12-01

    Rapid maxillary expansion (RME), indicated in the treatment of maxillary deficiency directs high forces to maxillary basal bone and to other adjacent skeletal bones. The aim of this study is to (i) evaluate stress distribution along craniofacial sutures and (ii) study the displacement of various craniofacial structures with rapid maxillary expansion therapy by using a Finite Element model. An analytical model was developed from a dried human skull of a 12 year old male. CT scan images of the skull were taken in axial direction parallel to the F-H plane at 1 mm interval, processed using Mimics software, required portion of the skull was exported into stereo-lithography model. ANSYS software was used to solve the mathematical equation. Contour plots of the displacement and stresses were obtained from the results of the analysis performed. At Node 47005, maximum X-displacement was 5.073 mm corresponding to the incisal edge of the upper central incisor. At Node 3971, maximum negative Y-displacement was -0.86 mm which corresponds to the anterior zygomatic arch, indicating posterior movement of craniofacial complex. At Node 32324, maximum negative Z-displacement was -0.92 mm representing the anterior and deepest convex portion of the nasal septum; indicating downward displacement of structures medial to the area of force application. Pyramidal displacement of maxilla was evident. Apex of pyramid faced the nasal bone and base was located on the oral side. Posterosuperior part of nasal cavity moved minimally in lateral direction and width of nasal cavity at the floor of the nose increased, there was downward and forward movement of maxilla with a tendency toward posterior rotation. Maximum von Mises stresses were found along midpalatal, pterygomaxillary, nasomaxillary and frontomaxillary sutures.

  10. Stress and displacement patterns in the craniofacial skeleton with rapid maxillary expansion—a finite element method study

    Directory of Open Access Journals (Sweden)

    J. Priyadarshini

    2017-07-01

    Full Text Available Abstract Background Rapid maxillary expansion (RME, indicated in the treatment of maxillary deficiency directs high forces to maxillary basal bone and to other adjacent skeletal bones. The aim of this study is to (i evaluate stress distribution along craniofacial sutures and (ii study the displacement of various craniofacial structures with rapid maxillary expansion therapy by using a Finite Element model. Methods An analytical model was developed from a dried human skull of a 12 year old male. CT scan images of the skull were taken in axial direction parallel to the F-H plane at 1 mm interval, processed using Mimics software, required portion of the skull was exported into stereo-lithography model. ANSYS software was used to solve the mathematical equation. Contour plots of the displacement and stresses were obtained from the results of the analysis performed. Results At Node 47005, maximum X-displacement was 5.073 mm corresponding to the incisal edge of the upper central incisor. At Node 3971, maximum negative Y-displacement was -0.86 mm which corresponds to the anterior zygomatic arch, indicating posterior movement of craniofacial complex. At Node 32324, maximum negative Z-displacement was -0.92 mm representing the anterior and deepest convex portion of the nasal septum; indicating downward displacement of structures medial to the area of force application. Conclusions Pyramidal displacement of maxilla was evident. Apex of pyramid faced the nasal bone and base was located on the oral side. Posterosuperior part of nasal cavity moved minimally in lateral direction and width of nasal cavity at the floor of the nose increased, there was downward and forward movement of maxilla with a tendency toward posterior rotation. Maximum von Mises stresses were found along midpalatal, pterygomaxillary, nasomaxillary and frontomaxillary sutures.

  11. Treatment of skeletal class III malocclusion using face mask therapy with alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol.

    Science.gov (United States)

    Rathi, Anand Ramchandra; Kumari, N Retna; Vadakkepuriyal, Kannan; Santhkumar, Madhu

    2015-01-01

    Class III malocclusion is very common malocclusion and can be due to maxillary retrusion, mandibular prognathism, or combination. Ellis and McNamara found a combination of maxillary retrusion and mandibular protrusion to be the most common skeletal relationship (30%). The treatment should be carried out as early as possible for permitting normal growth of the skeletal bases. Reverse pull head gear combined with maxillary expansion can effectively correct skeletal Class III malocclusion due to maxillary deficiency in growing patient. An eight-year-old female patient with chief complaint of prognathic mandible and anterior crossbite was successfully treated in duration of 5 months with facemask and expansion therapy based on Alternate Rapid Maxillary Expansion and Constriction (Alt-RAMEC) protocol.

  12. Treatment of skeletal class III malocclusion using face mask therapy with alternate rapid maxillary expansion and constriction (Alt-RAMEC protocol

    Directory of Open Access Journals (Sweden)

    Anand Ramchandra Rathi

    2015-01-01

    Full Text Available Class III malocclusion is very common malocclusion and can be due to maxillary retrusion, mandibular prognathism, or combination. Ellis and McNamara found a combination of maxillary retrusion and mandibular protrusion to be the most common skeletal relationship (30%. The treatment should be carried out as early as possible for permitting normal growth of the skeletal bases. Reverse pull head gear combined with maxillary expansion can effectively correct skeletal Class III malocclusion due to maxillary deficiency in growing patient. An eight-year-old female patient with chief complaint of prognathic mandible and anterior crossbite was successfully treated in duration of 5 months with facemask and expansion therapy based on Alternate Rapid Maxillary Expansion and Constriction (Alt-RAMEC protocol.

  13. Rapid prototyping-assisted maxillofacial reconstruction.

    Science.gov (United States)

    Peng, Qian; Tang, Zhangui; Liu, Ousheng; Peng, Zhiwei

    2015-05-01

    Rapid prototyping (RP) technologies have found many uses in dentistry, and especially oral and maxillofacial surgery, due to its ability to promote product development while at the same time reducing cost and depositing a part of any degree of complexity theoretically. This paper provides an overview of RP technologies for maxillofacial reconstruction covering both fundamentals and applications of the technologies. Key fundamentals of RP technologies involving the history, characteristics, and principles are reviewed. A number of RP applications to the main fields of oral and maxillofacial surgery, including restoration of maxillofacial deformities and defects, reduction of functional bone tissues, correction of dento-maxillofacial deformities, and fabrication of maxillofacial prostheses, are discussed. The most remarkable challenges for development of RP-assisted maxillofacial surgery and promising solutions are also elaborated.

  14. Remodelling of the palatal dome following rapid maxillary expansion (RME): laser scan-quantifications during a low growth period.

    Science.gov (United States)

    Muchitsch, A P; Winsauer, H; Wendl, B; Pichelmayer, M; Kuljuh, E; Szalay, A; Muchitsch, M

    2012-02-01

    To evaluate changes in the palatal vault after rapid maxillary expansion (RME) with bonded splint appliances. The sample comprised 24 children (12 boys and 12 girls) with mixed dentition (mean age 8.3 years; range 6.4-10.4 years). Following expansion, the splint appliance was used as a retainer for 6 months and then removed. Study casts were taken before RME (T0) and when the appliance was removed (T1). Then, 3D laser scans were taken to build complete 3D jaw models. Frontal cross sections were constructed at 53-63, 55-65 and 16-26, exported as coordinates, and finite element calculated to quantify their area, width and height. Maxillary length was also determined. Paired t-tests indicated statistically significant increases in the average palatal width (T1-T0=6.53-6.79 mm) and cross-sectional area (T1-T0=20.39-21.39 mm2) after RME (p0.99 (pmaxillary expansion distinctly increased mean palatal widths and cross-sectional areas. However, palatal height (55-65) and maxillary length decreased to a small extent. © 2012 John Wiley & Sons A/S.

  15. Immediate periodontal bone plate changes induced by rapid maxillary expansion in the early mixed dentition: CT findings

    Directory of Open Access Journals (Sweden)

    Daniela Gamba Garib

    2014-06-01

    Full Text Available OBJECTIVE: This study aimed at evaluating buccal and lingual bone plate changes caused by rapid maxillary expansion (RME in the mixed dentition by means of computed tomography (CT. METHODS: The sample comprised spiral CT exams taken from 22 mixed dentition patients from 6 to 9 years of age (mean age of 8.1 years presenting constricted maxillary arch treated with Haas-type expanders. Patients were submitted to spiral CT scan before expansion and after the screw activation period with a 30-day interval between T1 and T2. Multiplanar reconstruction was used to measure buccal and lingual bone plate thickness and buccal bone crest level of maxillary posterior deciduous and permanent teeth. Changes induced by expansion were evaluated using paired t test (p < 0.05. RESULTS: Thickness of buccal and lingual bone plates of posterior teeth remained unchanged during the expansion period, except for deciduous second molars which showed a slight reduction in bone thickness at the distal region of its buccal aspect. Buccal bone dehiscences were not observed in the supporting teeth after expansion. CONCLUSION: RME performed in mixed dentition did not produce immediate undesirable effects on periodontal bone tissues.

  16. Rapid maxillary expansion screws on the test bench--a pilot study.

    Science.gov (United States)

    Muchitsch, Alfred Peter; Wendl, B; Winsauer, H; Pichelmayer, M; Payer, M

    2011-06-01

    In order to apply high, short-term forces during rapid maxillary expansion (RME) to the sutures of the maxilla with minimum loss of force and without causing unwanted side-effects (dentoalveolar tipping, etc.), the appliance should be as rigid as possible. The retention arms of the RME screws, representing a particularly vulnerable and stressed weak point of RME appliances, were the focus of this laboratory technical study. Retention arms of 16 types of RME screws comprising four arms and one with eight arms were examined using a three-point bending test. According to their ability to absorb the applied bending loads, the screws were classified in product groups from 1 (highest) to 6 (lowest). Fifteen of the tested retention arms (stainless steel), despite having the same diameter (1.48-1.49 mm), differed up to 69.81 per cent between the highest (288.0 N) and lowest (169.6 N) maximum force parameters and up to 66.40 per cent between the highest (3325.9 N/mm(2)) and lowest (1998.7 N/mm(2)) maximum bending stress parameters. Due to optimum formability, though reduced rigidity, a titanium screw for nickel-sensitive patients (group 6) displayed the lowest force and bending tension values. The stainless steel double arms of the eight-arm screw device welded on both ends displayed the highest force data. The mean ductilities of the groups with the most and least rigid single steel arms differed by 22.77 per cent. Statistical analysis using the Pearson correlation coefficient revealed a significant indirect correlation between ductility and both maximum force (r = -0.780, P < 0.001) and maximum bending stress (r = -0.778, P < 0.001). The SUPERscrews, the Tiger Dental four-arm screw (group 1), and the eight-arm screw displayed the highest capacity to absorb an applied bending load. The screws in groups 3-6 appear acceptable for RME during the pre-pubertal period, whereas in the pubertal and post-pubertal period, groups 1 and 2 are sufficient. In early adulthood only the

  17. Effects of palate depth, modified arm shape, and anchor screw on rapid maxillary expansion: a finite element analysis.

    Science.gov (United States)

    Matsuyama, Yosuke; Motoyoshi, Mitsuru; Tsurumachi, Niina; Shimizu, Noriyoshi

    2015-04-01

    This study examined the effects of palate depth, modifications of the arm shape, and anchor screw placement in the mid-palatal area on rapid maxillary expansion (RME) using finite element (FE) analysis. Three-dimensional FE models were constructed that included the maxilla (cortical and cancellous bone), maxillary sinus, maxillary first molar and first premolar, periodontal membrane, and an RME appliance with arms, bands, and anchor screws. The expansion screws were activated 0.2mm transversely. The deepest palate model had the smallest lateral displacement of the tooth and expansion of the mid-palatal suture and the greatest strain of the arm among the models with different palate heights. The model with a larger diameter arm had the smallest arm strain among the models with various arm shapes. The model with an anchor screw had the greatest lateral displacement of the tooth and expansion of the mid-palatal suture among all models. For a deeper palate, the arm strain increased and the effect of RME decreased. Modified arm shapes such as a larger diameter arm, arms connected by a diagonal wire, a straight arm, and a shorter arm efficiently expanded the maxillary dental arch. Anchor screws increased the effect of RME, generated more and closer bodily movement of the tooth, and parallel expansion of the mid-palatal suture. The model with an anchor screw without arms decreased the displacement of the teeth compared to the models with arms, so the arms are necessary for effective RME. © The Author 2014. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  18. Improving Class II malocclusion as a side-effect of rapid maxillary expansion: a prospective clinical study.

    Science.gov (United States)

    Guest, Susan S; McNamara, James A; Baccetti, Tiziano; Franchi, Lorenzo

    2010-11-01

    The objective of this prospective clinical study was to evaluate the dentoalveolar and skeletal effects induced by rapid maxillary expansion (RME) therapy in mixed dentition patients with Class II Division 1 malocclusion compared with a matched untreated Class II Division 1 control group. The treatment sample consisted of cephalometric records of 50 patients with Class II malocclusion (19 boys, 31 girls) treated with an RME protocol including an acrylic splint expander. Some patients also had a removable mandibular Schwarz appliance or maxillary incisor bracketing as part of their treatment protocol. Postexpansion, the patients were stabilized with a removable maintenance plate or a transpalatal arch. The mean age at the start of treatment of the RME group was 8.8 years (T1), with a prephase 2 treatment cephalogram (T2) taken 4.0 years later. The control sample, derived from the records of 3 longitudinal growth studies, consisted of the cephalometric records of 50 Class II subjects (28 boys, 22 girls). The mean age of initial observation for the control group was 8.9 years, and the mean interval of observation was 4.1 years. All subjects in both groups were prepubertal at T1 and showed comparable prevalence rates for prepubertal or postpubertal stages at T2. Independent-sample Student t tests were used to examine between-group differences. Class II patients treated with the described bonded RME protocol showed statistically significant increases in mandibular length and advancement of pogonion relative to nasion perpendicular. The acrylic splint RME had significant effects on the anteroposterior relationship of the maxilla and the mandible, as shown by the improvements toward Class I in the maxillomandibular differential value, the Wits appraisal value, and the ANB angle. Patients treated with the bonded RME showed the greatest effects of therapy at the occlusal level, specifically highly significant improvement of Class II molar relationship and decrease in

  19. Miniscrew-assisted rapid palatal expander (MARPE: the quest for pure orthopedic movement

    Directory of Open Access Journals (Sweden)

    Hideo Suzuki

    Full Text Available ABSTRACT The midpalatal suture has bone margins with thick connective tissue interposed between them, and it does not represent the fusion of maxillary palatal processes only, but also the fusion of palatal processes of the jaws and horizontal osseous laminae of palatal bones. Changing it implies affecting neighboring areas. It has got three segments that should be considered by all clinical analyses, whether therapeutic or experimental: the anterior segment (before the incisive foramen, or intermaxillary segment, the middle segment (from the incisive foramen to the suture transversal to the palatal bone and the posterior segment (after the suture transversal to the palatal bone . Rapid palatal expansion might be recommended for patients at the final pubertal growth stage, in addition to adult patients with maxillary constriction. It represents a treatment solution that can potentially avoid surgical intervention. When performed in association with rapid palatal expanders, it might enhance the skeletal effects of the latter. Of the various designs of expansion appliances, MARPE (miniscrew-assisted rapid palatal expander has been modified in order to allow its operational advantages and outcomes to become familiar in the clinical practice.

  20. Model of oronasal rehabilitation in children with obstructive sleep apnea syndrome undergoing rapid maxillary expansion: Research review

    Directory of Open Access Journals (Sweden)

    Luca Levrini

    2014-12-01

    Full Text Available Rapid maxillary expansion (RME is a widely used practice in orthodontics. Scientific evidence shows that RME can be helpful in modifying the breathing pattern in mouth-breathing patients. In order to promote the restoration of physiological breathing we have developed a rehabilitation program associated with RME in children. The aim of the study was a literature review and a model of orofacial rehabilitation in children with obstructive sleep apnea undergoing treatment with rapid maxillary expansion. Muscular training (local exercises and general ones is the key factor of the program. It also includes hygienic and behavior instructions as well as other therapeutic procedures such as rhinosinusal washes, a postural re-education (Alexander technique and, if necessary, a pharmacological treatment aimed to improve nasal obstruction. The program should be customized for each patient. If RME is supported by an adequate functional rehabilitation, the possibility to change the breathing pattern is considerably amplified. Awareness, motivation and collaboration of the child and their parents, as well as the cooperation among specialists, such as orthodontist, speech therapist, pediatrician and otolaryngologist, are necessary conditions to achieve the goal.

  1. Short-term evaluation of tegumentary changes of the nose in oral breathers undergoing rapid maxillary expansion.

    Science.gov (United States)

    Badreddine, Fauze Ramez; Fujita, Reginaldo Raimundo; Cappellette, Mario

    2017-06-26

    Rapid maxillary expansion is an orthodontic and orthopedic procedure that can change the form and function of the nose. The soft tissue of the nose and its changes can influence the esthetics and the stability of the results obtained by this procedure. The objective of this study was to assess the changes in nose dimensions after rapid maxillary expansion (RME) in oral breathers with maxillary atresia, using a reliable and reproducible methodology through computed tomography. A total of 30 mouth-breathing patients with maxillary atresia were analyzed and divided into a treatment group who underwent RME (20 patients, 10 of which were male and 10 female, with a MA of 8.9 years and a SD of 2.16, ranging from 6.5 to 12.5 years) and a Control Group (10 patients, 5 of which were male and 5 female, with a MA of 9.2 years, SD of 2.17, ranging from 6.11 to 13.7 years). In the treatment group, multislice computed tomography scans were obtained at the start of the treatment (T1) and 3 months after expansion (T2). The patients of the control group were submitted to the same exams at the same intervals of time. Four variables related to soft tissue structures of the nose were analyzed (alar base width, alar width, height of soft tissue of the nose and length of soft tissue of the nose), and the outcomes between T1 and T2 were compared using Osirix MD software. In the TG, the soft tissues of the nose exhibited significant increases in all variables studied (p0.05). In the treatment group, mean alar base width increased by 4.87% (p=0.004), mean alar width increased by 4.04% (p=0.004), mean height of the soft tissues of the nose increased by 4.84% (p=0.003) and mean length of the soft tissues of the nose increased by 4.29% (p=0.012). In short-term, RME provided a statistically significant increase in the dimensions of the soft tissues of the nose. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All

  2. Camouflage treatment of skeletal class III malocclusion with asymmetry using a bone-borne rapid maxillary expander.

    Science.gov (United States)

    Seo, Yu-Jin; Chung, Kyu-Rhim; Kim, Seong-Hun; Nelson, Gerald

    2015-03-01

    This case report presents the successful use of palatal mini-implants for rapid maxillary expansion and mandibular distalization in a skeletal Class III malocclusion. The patient was a 13-year-old girl with the chief complaint of facial asymmetry and a protruded chin. Camouflage orthodontic treatment was chosen, acknowledging the possibility of need for orthognathic surgery after completion of her growth. A bone-borne rapid expander (BBRME) was used to correct the transverse discrepancy and was then used as indirect anchorage for distalization of the lower dentition with Class III elastics. As a result, a Class I occlusion with favorable inclination of the upper teeth was achieved without any adverse effects. The total treatment period was 25 months. Therefore, BBRME can be considered an alternative treatment in skeletal Class III malocclusion.

  3. A prospective study of the short-term treatment effects of the acrylic-splint rapid maxillary expander combined with the lower Schwarz appliance.

    Science.gov (United States)

    Wendling, Lisa K; McNamara, James A; Franchi, Lorenzo; Baccetti, Tiziano

    2005-01-01

    This prospective clinical study evaluated the short-term treatment effects of acrylic-splint rapid maxillary expander in conjunction with lower Schwarz appliance (RME-Sz) therapy to the acrylic-splint rapid maxillary expansion alone (RME-only group). Pretreatment and posttreatment lateral cephalograms were analyzed for 25 RME patients and 19 RME-Sz patients. The average time between films ranged between nine and 12 months. Statistical comparisons of the treatment changes in the RME-only and RME-Sz groups were performed by means of independent sample t-tests (P appliance prevented the mesial movement of the lower molars during the treatment period.

  4. Changes in skeletal and dental relationship in Class II Division I malocclusion after rapid maxillary expansion: a prospective study.

    Science.gov (United States)

    Baratieri, Carolina; Alves, Matheus; Bolognese, Ana Maria; Nojima, Matilde C G; Nojima, Lincoln I

    2014-01-01

    To assess skeletal and dental changes immediately after rapid maxillary expansion (RME) in Class II Division 1 malocclusion patients and after a retention period, using cone beam computed tomography (CBCT) imaging. Seventeen children with Class II, Division 1 malocclusion and maxillary skeletal transverse deficiency underwent RME following the Haas protocol. CBCT were taken before treatment (T1), at the end of the active expansion phase (T2) and after a retention period of 6 months (T3). The scanned images were measured anteroposteriorly (SNA, SNB, ANB, overjet and MR) and vertically (N-ANS, ANS-Me, N-Me and overbite). Significant differences were identified immediately after RME as the maxilla moved forward, the mandible moved downward, overjet increased and overbite decreased. During the retention period, the maxilla relapsed backwards and the mandible was displaced forward, leaving patients with an overall increase in anterior facial height. RME treatment allowed more anterior than inferior positioning of the mandible during the retention period, thus significantly improving Class II dental relationship in 75% of the patients evaluated.

  5. Can rapid maxillary expansion cause auditory improvement in children and adolescents with hearing loss? A systematic review.

    Science.gov (United States)

    Fagundes, Nathalia Carolina Fernandes; Rabello, Nicole Melres; Maia, Lucianne Cople; Normando, David; Mello, Karina Corrêa Flexa Ribeiro

    2017-11-01

    To evaluate whether the use of palatal expansion techniques can influence hearing loss in children and adolescents with previous hearing impairment. Electronic searches in PubMed, Scopus, Web of Science, The Cochrane Library, Lilacs, OpenGrey, and Google Scholar were performed with a controlled vocabulary and free-text terms relating to palatal expansion and hearing loss. No language or time restrictions were imposed. Clinical trials that focused on human patients treated with rapid or semirapid maxillary expansion in children and teenagers with hearing loss were included. Data extraction was undertaken by two authors, with conflict resolution by a third author. Risk of bias assessment and data extraction were performed on the selected studies. Seventy-four citations were retrieved by the search. Initially, 12 studies were selected according to the eligibility criteria, but three studies were excluded because of the presence of adults, absence of hearing level evaluation, and oversampling, resulting in nine studies. The mean improvement in hearing levels varied from 2 to 19 dB among the studies. The risk of bias varied from low to moderate risk. The evidence indicated that there was a hearing improvement after maxillary expansion in patients with hearing loss in the evaluated studies, although more controlled and randomized studies are necessary to investigate this issue further.

  6. Changes in skeletal and dental relationship in Class II Division I malocclusion after rapid maxillary expansion: a prospective study

    Directory of Open Access Journals (Sweden)

    Carolina Baratieri

    2014-06-01

    Full Text Available OBJECTIVE: To assess skeletal and dental changes immediately after rapid maxillary expansion (RME in Class II Division 1 malocclusion patients and after a retention period, using cone beam computed tomography (CBCT imaging. METHODS: Seventeen children with Class II, Division 1 malocclusion and maxillary skeletal transverse deficiency underwent RME following the Haas protocol. CBCT were taken before treatment (T1, at the end of the active expansion phase (T2 and after a retention period of 6 months (T3. The scanned images were measured anteroposteriorly (SNA, SNB, ANB, overjet and MR and vertically (N-ANS, ANS-Me, N-Me and overbite. RESULTS: Significant differences were identified immediately after RME as the maxilla moved forward, the mandible moved downward, overjet increased and overbite decreased. During the retention period, the maxilla relapsed backwards and the mandible was displaced forward, leaving patients with an overall increase in anterior facial height. CONCLUSION: RME treatment allowed more anterior than inferior positioning of the mandible during the retention period, thus significantly improving Class II dental relationship in 75% of the patients evaluated.

  7. Dentoskeletal outcomes of a rapid maxillary expander with differential opening in patients with bilateral cleft lip and palate: A prospective clinical trial.

    Science.gov (United States)

    Garib, Daniela; Lauris, Rita De Cássia Moura Carvalho; Calil, Louise Resti; Alves, Arthur César De Medeiros; Janson, Guilherme; De Almeida, Araci Malagodi; Cevidanes, Lúcia Helena Soares; Lauris, José Roberto Pereira

    2016-10-01

    The purpose of this 2-arm parallel study was to evaluate the dentoskeletal effects of rapid maxillary expansion with differential opening (EDO) compared with the hyrax expander in patients with complete bilateral cleft lip and palate. A sample of patients with complete bilateral cleft lip and palate was prospectively and consecutively recruited. Eligibility criteria included participants in the mixed dentition with lip and palate repair performed during early childhood and maxillary arch constriction with a need for maxillary expansion before the alveolar bone graft procedure. The participants were consecutively divided into 2 study groups. The experimental and control groups comprised patients treated with rapid maxillary expansion using EDO and the hyrax expander, respectively. Cone-beam computed tomography examinations and digital dental models of the maxillary dental arches were obtained before expansion and 6 months postexpansion. Standardized cone-beam computed tomography coronal sections were used for measuring maxillary transverse dimensions and posterior tooth inclinations. Digital dental models were used for assessing maxillary dental arch widths, arch perimeters, arch lengths, palatal depths, and posterior tooth inclinations. Blinding was used only during outcome assessment. The chi-square test was used to compare the sex ratios between groups (P variables before expansion. No significant differences were found between the EDO and the hyrax expander groups regarding skeletal changes. The EDO promoted significantly greater increases of intercanine width (difference, 3.63 mm) and smaller increases in canine buccal tipping than the conventional hyrax expander. No serious harm was observed other than transitory variable pressure sensations on the maxillary alveolar process in both groups. The EDO produced skeletal changes similar to the conventional hyrax expander. The differential expander is an adequate alternative to conventional rapid maxillary

  8. Cephalometric evaluation of the hyoid triangle before and after maxillary rapid expansion in patients with skeletal class II, mixed dentition, and infantile swallowing.

    Science.gov (United States)

    Parisella, Valeria; Vozza, Iole; Capasso, Francesca; Luzzi, Valeria; Ierardo, Gaetano; Nofroni, Italo; Polimeni, Antonella

    2012-07-01

    Rocabado's hyoid triangle is the only cephalometric parameter that can assess the effects of orthodontic treatment on tongue posture. To evaluate the restoration of tongue posture and function by conducting a cephalometric assessment of the hyoid triangle before and after rapid maxillary expansion. Sixty-four healthy patients aged 6-11 years with skeletal class II malocclusion, mixed dentition, and infantile swallowing took part in this study. They submitted to lateral cephalometric radiography before and after orthodontic maxillary rapid expansion, in order to assess the resulting changes in the proportions of the hyoid triangle (following Rocabado's parameters). The cephalometric findings were compared according to sex, age, and divergence using the chi-square McNemar test at the 5% significance level (ptriangle was modified by the orthodontic maxillary expansion, reconditioning of tongue posture and function particularly among male, aged 6-7 years old with skeletal class II malocclusion, mixed dentition, and infantile swallowing.

  9. Computer-assisted orthognathic surgery: waferless maxillary positioning, versatility, and accuracy of an image-guided visualisation display.

    Science.gov (United States)

    Zinser, Max J; Mischkowski, Robert A; Dreiseidler, Timo; Thamm, Oliver C; Rothamel, Daniel; Zöller, Joachim E

    2013-12-01

    There may well be a shift towards 3-dimensional orthognathic surgery when virtual surgical planning can be applied clinically. We present a computer-assisted protocol that uses surgical navigation supplemented by an interactive image-guided visualisation display (IGVD) to transfer virtual maxillary planning precisely. The aim of this study was to analyse its accuracy and versatility in vivo. The protocol consists of maxillofacial imaging, diagnosis, planning of virtual treatment, and intraoperative surgical transfer using an IGV display. The advantage of the interactive IGV display is that the virtually planned maxilla and its real position can be completely superimposed during operation through a video graphics array (VGA) camera, thereby augmenting the surgeon's 3-dimensional perception. Sixteen adult class III patients were treated with by bimaxillary osteotomy. Seven hard tissue variables were chosen to compare (ΔT1-T0) the virtual maxillary planning (T0) with the postoperative result (T1) using 3-dimensional cephalometry. Clinically acceptable precision for the surgical planning transfer of the maxilla (orthognathic planning. Copyright © 2013 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  10. Miniscrew-assisted rapid palatal expansion for managing arch perimeter in an adult patient

    Directory of Open Access Journals (Sweden)

    Amanda Carneiro da Cunha

    Full Text Available ABSTRACT Introduction: Etiology of dental crowding may be related to arch constriction in diverse dimensions, and an appropriate manipulation of arch perimeter by intervening in basal bone discrepancies cases, may be a key for crowding relief, especially when incisors movement is limited due to underlying pathology, periodontal issues or restrictions related to soft tissue profile. Objectives: This case report illustrates a 24-year old woman, with maxillary transverse deficiency, upper and lower arches crowding, Class II, division 1, subdivision right relationship, previous upper incisors traumatic episode and straight profile. A non-surgical and non-extraction treatment approach was feasible due to the miniscrew-assisted rapid palatal expansion technique (MARPE. Methods: The MARPE appliance consisted of a conventional Hyrax expander supported by four orthodontic miniscrews. A slow expansion protocol was adopted, with an overall of 40 days of activation and a 3-month retention period. Intrusive traction miniscrew-anchored mechanics were used for correcting the Class II subdivision relationship, managing lower arch perimeter and midline deviation before including the upper central incisors. Results: Post-treatment records show an intermolar width increase of 5 mm, bilateral Class I molar and canine relationships, upper and lower crowding resolution, coincident dental midlines and proper intercuspation. Conclusions: The MARPE is an effective treatment approach for managing arch-perimeter deficiencies related to maxillary transverse discrepancies in adult patients.

  11. Application of computer-aided three-dimensional skull model with rapid prototyping technique in repair of zygomatico-orbito-maxillary complex fracture.

    Science.gov (United States)

    Li, Wei Zhong; Zhang, Mei Chao; Li, Shao Ping; Zhang, Lei Tao; Huang, Yu

    2009-06-01

    With the advent of CAD/CAM and rapid prototyping (RP), a technical revolution in oral and maxillofacial trauma was promoted to benefit treatment, repair of maxillofacial fractures and reconstruction of maxillofacial defects. For a patient with zygomatico-facial collapse deformity resulting from a zygomatico-orbito-maxillary complex (ZOMC) fracture, CT scan data were processed by using Mimics 10.0 for three-dimensional (3D) reconstruction. The reduction design was aided by 3D virtual imaging and the 3D skull model was reproduced using the RP technique. In line with the design by Mimics, presurgery was performed on the 3D skull model and the semi-coronal incision was taken for reduction of ZOMC fracture, based on the outcome from the presurgery. Postoperative CT and images revealed significantly modified zygomatic collapse and zygomatic arch rise and well-modified facial symmetry. The CAD/CAM and RP technique is a relatively useful tool that can assist surgeons with reconstruction of the maxillofacial skeleton, especially in repairs of ZOMC fracture.

  12. Non-surgical treatment of transverse deficiency in adults using Microimplant-assisted Rapid Palatal Expansion (MARPE).

    Science.gov (United States)

    Brunetto, Daniel Paludo; Sant'Anna, Eduardo Franzzotti; Machado, Andre Wilson; Moon, Won

    2017-02-01

    Maxillary transverse deficiency is a highly prevalent malocclusion present in all age groups, from primary to permanent dentition. If not treated on time, it can aggravate and evolve to a more complex malocclusion, hindering facial growth and development. Aside from the occlusal consequences, the deficiency can bring about serious respiratory problems as well, due to the consequent nasal constriction usually associated. In growing patients, this condition can be easily handled with a conventional rapid palatal expansion. However, mature patients are frequently subjected to a more invasive procedure, the surgically-assisted rapid palatal expansion (SARPE). More recently, researches have demonstrated that it is possible to expand the maxilla in grown patients without performing osteotomies, but using microimplants anchorage instead. This novel technique is called microimplant-assisted rapid palatal expansion (MARPE). The aim of the present article was to demonstrate and discuss a MARPE technique developed by Dr. Won Moon and colleagues at University of California - Los Angeles (UCLA). All laboratory and clinical steps needed for its correct execution are thoroughly described. For better comprehension, a mature patient case is reported, detailing all the treatment progress and results obtained. It was concluded that the demonstrated technique could be an interesting alternative to SARPE in the majority of non-growing patients with maxillary transverse deficiency. The present patient showed important occlusal and respiratory benefits following the procedure, without requiring any surgical intervention.

  13. Non-surgical treatment of transverse deficiency in adults using Microimplant-assisted Rapid Palatal Expansion (MARPE

    Directory of Open Access Journals (Sweden)

    Daniel Paludo Brunetto

    Full Text Available ABSTRACT Introduction: Maxillary transverse deficiency is a highly prevalent malocclusion present in all age groups, from primary to permanent dentition. If not treated on time, it can aggravate and evolve to a more complex malocclusion, hindering facial growth and development. Aside from the occlusal consequences, the deficiency can bring about serious respiratory problems as well, due to the consequent nasal constriction usually associated. In growing patients, this condition can be easily handled with a conventional rapid palatal expansion. However, mature patients are frequently subjected to a more invasive procedure, the surgically-assisted rapid palatal expansion (SARPE. More recently, researches have demonstrated that it is possible to expand the maxilla in grown patients without performing osteotomies, but using microimplants anchorage instead. This novel technique is called microimplant-assisted rapid palatal expansion (MARPE. Objective: The aim of the present article was to demonstrate and discuss a MARPE technique developed by Dr. Won Moon and colleagues at University of California - Los Angeles (UCLA. Methods: All laboratory and clinical steps needed for its correct execution are thoroughly described. For better comprehension, a mature patient case is reported, detailing all the treatment progress and results obtained. Conclusion: It was concluded that the demonstrated technique could be an interesting alternative to SARPE in the majority of non-growing patients with maxillary transverse deficiency. The present patient showed important occlusal and respiratory benefits following the procedure, without requiring any surgical intervention.

  14. Effects of strontium ranelate on bone formation in the mid-palatal suture after rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Zhao SY

    2015-05-01

    Full Text Available Shuya Zhao,1,* Xuxia Wang,2,* Na Li,3 Yun Chen,1 Yuran Su,1 Jun Zhang1 1Department of Orthodontics, 2Department of Oral and Maxillofacial Surgery, Faculty of Stomatology, Shandong University; 3Department of Orthodontics, Shandong Provincial Qianfoshan Hospital, Jinan, People’s Republic of China *These authors contributed equally to this work Background: The aim of this experimental study was to investigate the effects of strontium ranelate on bone regeneration in the mid-palatal suture in response to rapid maxillary expansion (RME.Methods: Thirty-six male 6-week-old Wistar rats were randomly divided into three groups, ie, an expansion only (EO group, an expansion plus strontium ranelate (SE group, and a control group. An orthodontic appliance was set between the right and left upper molars of rats with an initial expansive force of 0.98 N. Rats in the SE group were administered strontium ranelate (600 mg/kg body weight and then euthanized in batches on days 4, 7, and 10. Morphological changes in the mid-palatal suture were investigated using micro-computed tomography and hematoxylin and eosin staining after RME. Bone morphogenetic protein-2 expression in the suture was also examined to evaluate bone formation in the mid-palatal suture. Image-Pro Plus software was then used to determine the mean optical density of the immunohistochemical images. Analysis of variance was used for statistical evaluation at the P<0.05 level.Results: With expansive force, the mid-palatal suture was expanded, but there was no statistically significant difference (P>0.05 between the SE and EO groups. The bone volume of the suture decreased after RME, but was higher in the SE group than in the EO group on days 7 and 10. Further, expression of bone morphogenetic protein-2 in the SE group was higher than in the other two groups (P<0.05.Conclusion: Strontium ranelate may hasten new bone formation in the expanded mid-palatal suture, which may be therapeutically

  15. CBCT of skeletal changes following rapid maxillary expansion to increase arch-length with a development-dependent bonded or banded appliance.

    Science.gov (United States)

    Kanomi, Ryuzo; Deguchi, Toru; Kakuno, Eriko; Takano-Yamamoto, Teruko; Roberts, W Eugene

    2013-09-01

    To assess the three-dimensional (3D) skeletal response to a standardized 5 mm of rapid maxillary expansion (RME) in growing children (6-15 years) with maxillary width deficiency and crowding. A bonded appliance was used prior to the eruption of the maxillary first premolars (Mx4s), and a banded appliance was used thereafter. A consecutive sample of 89 patients (29 boys and 60 girls) from a large pediatric dentistry and orthodontics practice was divided into four groups: 1) 6-8 years old (n = 26), 2) 9-11 years old with unerupted Mx4s (n = 21), 3) 9-11 years with erupted Mx4s (n = 23), and 4) 12-15 years (n = 19). For all patients, the 3D evaluation of dental and skeletal effects was performed with cone-beam computed tomography (CBCT). For both appliances in all patients, CBCT confirmed a triangular pattern of expansion in both the frontal and sagittal planes. Overall, both appliances produced significant maxillary expansion (>80% of the 5-mm activation), but older children showed a progressively more dental (less skeletal) response. Comparison of the two types of expanders in the crossover sample, children aged 9-11 years, showed that the bonded RME produced the most efficient skeletal expansion in the preadolescent sample. Increased maxillary width at the level of the zygomaticomaxillary suture was the best indicator for development of maxillary arch circumference. Development-dependent appliances (bonded RPE before Mx4s erupt, and a banded device thereafter) provided optimal RME treatment for all children from age 6-15 years.

  16. Cephalometric variables used to predict the success of interceptive treatment with rapid maxillary expansion and face mask. A longitudinal study

    Directory of Open Access Journals (Sweden)

    Daniele Nóbrega Nardoni

    2015-02-01

    Full Text Available INTRODUCTION: Prognosis is the main limitation of interceptive treatment of Class III malocclusions. The interceptive procedures of rapid maxillary expansion (RME and face mask therapy performed in early mixed dentition are capable of achieving immediate overcorrection and maintenance of facial and occlusal morphology for a few years. Individuals presenting minimal acceptable faces at growth completion are potential candidates for compensatory orthodontic treatment, while those with facial involvement should be submitted to orthodontic decompensation for orthognathic surgery. OBJECTIVES: To investigate cephalometric variables that might predict the outcomes of orthopedic treatment with RME and face mask therapy (FM. METHODS: Cephalometric analysis of 26 Class III patients (mean age of 8 years and 4 months was performed at treatment onset and after a mean period of 6 years and 10 months at pubertal growth completion, including a subjective facial analysis. Patients was divided into two groups: success group (21 individuals and failure group (5 individuals. Discriminant analysis was applied to the cephalometric values at treatment onset. Two predictor variables were found by stepwise procedure. RESULTS: Orthopedic treatment of Class III malocclusion may have unfavorable prognosis at growth completion whenever initial cephalometric analysis reveals increased lower anterior facial height (LAFH combined with reduced angle between the condylar axis and the mandibular plane (CondAx.MP. CONCLUSION: The results of treatment with RME and face mask therapy at growth completion in Class III patients could be predicted with a probability of 88.5%.

  17. Complete Maxillary Crossbite Correction with a Rapid Palatal Expansion in Mixed Dentition Followed by a Corrective Orthodontic Treatment

    National Research Council Canada - National Science Library

    Tanaka, Orlando Motohiro; Fornazari, Isabelle Adad; Parra, Ariane Ximenes Graciano; Castilhos, Bruno Borges de; Franco, Ademir

    2016-01-01

    .... In phase I, the patient was treated with a modified Haas-type palatal expander, which provided a clinically significant palatal expansion and increased the maxillary arch perimeter with favorable...

  18. Strategic camouflage treatment of skeletal Class III malocclusion (mandibular prognathism) using bone-borne rapid maxillary expansion and mandibular anterior subapical osteotomy.

    Science.gov (United States)

    Seo, Yu-Jin; Lin, Lu; Kim, Seong-Hun; Chung, Kyu-Rhim; Nelson, Gerald

    2016-01-01

    This case report presents the camouflage treatment that successfully improved the facial profile of a patient with a skeletal Class III malocclusion using bone-borne rapid maxillary expansion and mandibular anterior subapical osteotomy. The patient was an 18-year-old woman with chief complaints of crooked teeth and a protruded jaw. Camouflage treatment was chosen because she rejected orthognathic surgery under general anesthesia. A hybrid type of bone-borne rapid maxillary expander with palatal mini-implants was used to correct the transverse discrepancy, and a mandibular anterior subapical osteotomy was conducted to achieve proper overjet with normal incisal inclination and to improve her lip and chin profile. As a result, a Class I occlusion with a favorable inclination of the anterior teeth and a good esthetic profile was achieved with no adverse effects. Therefore, the hybrid type of bone-borne rapid maxillary expander and a mandibular anterior subapical osteotomy can be considered effective camouflage treatment of a skeletal Class III malocclusion, providing improved inclination of the dentition and lip profile. Copyright © 2016 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  19. Comparison and evaluation of stresses generated by rapid maxillary expansion and the implant-supported rapid maxillary expansion on the craniofacial structures using finite element method of stress analysis.

    Science.gov (United States)

    Jain, Varun; Shyagali, Tarulatha R; Kambalyal, Prabhuraj; Rajpara, Yagnesh; Doshi, Jigar

    2017-12-01

    The study aimed to evaluate and compare the stress distribution and 3-dimensional displacements along the craniofacial sutures in between the Rapid maxillary Expansion (RME) and Implant supported RME (I-RME). METHODS: Finite element model of the skull and the implants were created using ANSYS software. The finite element model thus built composed of 537692 elements and 115694 nodes in RME model & 543078 elements and 117948 nodes with implants model. The forces were applied on the palatal surface of the posterior teeth to cause 5mm of transverse displacement on either side of the palatal halves, making it a total of 10mm. The stresses and the displacement values were obtained and interpreted. Varying pattern of stress and the displacements with both positive and negative values were seen. The maximum displacement was seen in the case of plain RME model and that too at Pterygomaxillary suture and Mid-palatal suture in descending order. In the case of I-RME maximum displacement was seen at Zygomaticomaxillary suture followed by Pterygomaxillary suture. The displacements produced in all the three planes of space for the plain RME model were greater in comparison to the Implant Supported RME model. And the stresses remained high for all the sutures in case of an I-RME. There is a definite difference in the stress and the displacement pattern produced by RME and I-RME model and each can be used according to the need of the patient. The stresses generated in case of conventional RME were considerably less than that of the I-RME for all the sutures.

  20. Analysis of the dentoalveolar effects of slow and rapid maxillary expansion in complete bilateral cleft lip and palate patients: a randomized clinical trial.

    Science.gov (United States)

    de Medeiros Alves, Arthur César; Garib, Daniela Gamba; Janson, Guilherme; de Almeida, Araci Malagodi; Calil, Louise Resti

    2016-09-01

    The purpose of this study was to compare the dentoalveolar effects of slow (SME) and rapid (RME) maxillary expansions in patients with complete bilateral cleft lip and palate (BCLP). A sample of 50 patients with BCLP and maxillary arch constriction was randomly and equally allocated into two groups. Group SME comprised patients (mean age of 8.8 years) treated with quad-helix appliance. Group RME comprised individuals (mean age of 8.9 years) treated with Hyrax expander. Digital dental models obtained immediately pre-expansion (T1) and 6 months after the active expansion period (T2) were used for measuring maxillary dental arch widths, arch perimeter, arch length, palatal depth, buccolingual inclination of posterior teeth and differential amount of expansion accomplished at the canine and molar regions. Inter-phase and intergroup comparisons were performed using paired t tests and t tests, respectively (p < 0.05). SME and RME caused significant increase of arch widths and arch perimeter. Arch length and palatal depth decreased nonsignificantly with SME but significantly with RME. Buccal tooth inclination was significant only for maxillary deciduous canines in both groups. The quad-helix appliance showed a significant differential expansion between anterior and posterior regions. No differences were observed between SME and RME for all variables. Differences were not found between the dentoalveolar effects of SME and RME in patients with BCLP. SME demanded a greater therapy time compared to RME. Both expansion procedures can be similarly indicated to correct maxillary arch constriction in patients with BCLP in the mixed dentition.

  1. Is alternate rapid maxillary expansion and constriction an effective protocol in the treatment of Class III malocclusion? A systematic review.

    Science.gov (United States)

    Pithon, Matheus Melo; Santos, Nathalia de Lima; Santos, Camila Rangel Barreto Dos; Baião, Felipe Carvalho Souza; Pinheiro, Murilo Costa Rangel; Matos, Manoel; Souza, Ianderlei Andrade; Paula, Rafael Pereira de

    2016-01-01

    the treatment of Class III malocclusion in early age is one of the greatest challenges for orthodontists, and the establishment of more effective treatment method is a constant concern for these professionals. Thus, the objective of this systematic review is to verify the effectiveness of the therapy protocol for alternate rapid maxillary expansion and constriction (Alt-RAMEC) in the early treatment of Class III malocclusion. searches were performed in the following electronic databases: Cochrane Library, Medline (EBSCO and PubMed), SciELO, LILACS and Scopus. The following inclusion criteria were used: in vivo studies conducted with early intervention (patient in craniofacial development phase) with the use of the Alt-RAMEC protocol. Reviews, case reports, editorials, and studies with syndromic patients or under use of systemic drug were excluded. Duplicates were also excluded. The studies were assessed for methodological quality using the Cochrane tool for assessment of risk of bias, and classified as high or low risk of bias. 53 articles were found. Duplicates exclusion was thus performed and 35 articles remained. After inclusion analysis, only 5 matched the criteria. Two articles were classified as low risk of bias and three as high risk of bias. It was observed that the Alt-RAMEC enable protraction in less time and with better results, promoting greater effectiveness in the protraction treatment of Class III malocclusion. Although there is positive evidence of the effectiveness of early treatment with the Alt-RAMEC protocol in patients with Class III malocclusion, further studies are needed to confirm its effectiveness using long-term methodology.

  2. Craniofacial and upper airway morphology in pediatric sleep-disordered breathing and changes in quality of life with rapid maxillary expansion.

    Science.gov (United States)

    Katyal, Vandana; Pamula, Yvonne; Daynes, Cathal N; Martin, James; Dreyer, Craig W; Kennedy, Declan; Sampson, Wayne J

    2013-12-01

    The association between pediatric sleep-disordered breathing caused by upper airway obstruction and craniofacial morphology is poorly understood and contradictory. The aims of this study were to evaluate the prevalence of children at risk for sleep-disordered breathing, as identified in an orthodontic setting by validated screening questionnaires, and to examine associations with their craniofacial and upper airway morphologies. A further aim was to assess the change in quality of life related to sleep-disordered breathing for affected children undergoing rapid maxillary expansion to correct a palatal crossbite or widen a narrow maxilla. A prospective case-control study with children between 8 and 17 years of age (n = 81) at an orthodontic clinic was undertaken. The subjects were grouped as high risk or low risk for sleep-disordered breathing based on the scores from a validated 22-item Pediatric Sleep Questionnaire and the Obstructive Sleep Apnea-18 Quality of Life Questionnaire. Variables pertaining to a screening clinical examination, cephalometric assessment, and dental cast analysis were tested for differences between the 2 groups at baseline. Ten children who underwent rapid maxillary expansion were followed longitudinally until removal of the appliance approximately 9 months later with a repeated Obstructive Sleep Apnea-18 Quality of Life Questionnaire. All data were collected blinded to the questionnaire results. The frequency of palatal crossbite involving at least 3 teeth was significantly higher in the high-risk group at 68.2%, compared with the low-risk group at 23.2% (P children in the low-risk group at baseline (P maxillary intercanine, maxillary interfirst premolar, maxillary interfirst molar, mandibular intercanine, and mandibular interfirst premolar widths were reduced in the high-risk group compared with the low-risk group by 4.22 mm (P Children treated with rapid maxillary expansion showed an average improvement of 14% in quality of life

  3. Assessment of the dental and skeletal effects of fan-type rapid maxillary expansion screw and Hyrax screw on craniofacial structures

    Directory of Open Access Journals (Sweden)

    Umarevathi Gopalakrishnan

    2017-01-01

    Full Text Available Aims and Objectives: The purpose of the study was to assess the skeletal and dental effects of fan-type rapid maxillary expansion (RME appliance and Hyrax RME appliance on the craniofacial structures. Materials and Methods: The sample of the study included 12 patients with constricted maxillary arches. Acrylic bonded type of attachment was used for both groups. Changes in sagittal, vertical, and transverse relationship were assessed with lateral and frontal cephalograms, respectively. Intercanine and intermolar widths were measured with stone models. Pre- and immediate post-treatment records were statistically analyzed with Wilcoxon signed-rank test. The differences between the groups were evaluated using Mann–Whitney U-test. Since the data pertaining to intercanine width and intermolar width were normally distributed, parametric test of signifi cance (unpaired t-test was used to compare them. Results: Results showed that Hyrax presented with signifi cantly greater increments for both nasal cavity width and maxillary width when compared to fan-type RME. Both groups had retroclination of incisors. The increase in the intercanine width was almost similar in both groups. Conclusion: Fan-type RME caused only minimal expansion of the intermolar width when compared to the Hyrax. The ratio between the intercanine and intermolar width expansion was nearly 4:1 in the fan-type RME and 0.75:1 in Hyrax.

  4. Effects of rapid maxillary expansion and mandibular advancement on upper airways in Marfan's syndrome children: a home sleep study and cephalometric evaluation.

    Science.gov (United States)

    Taddei, M; Alkhamis, N; Tagariello, T; D'Alessandro, G; Mariucci, E M; Piana, G

    2015-12-01

    Evaluation of the effects of rapid maxillary expansion and mandibular advancement using Propulsor Universal Light appliance on the upper airways in Marfan's syndrome children through home sleep studies, Epworth Sleepiness Scale questionnaire, and cephalometric analysis of the upper airways on lateral radiographs. The study sample consisted of 30 children with Marfan's syndrome, and the control group consisted of 30 untreated and matched children. For Marfan subjects, data were taken at different time points compared to treatment: at T0 (before treatment), T1 (after rapid maxillary expansion), and T2 (after mandibular advancement). For control subjects, data were taken at similar intervals, at three follow-up visits: at T0 (as a starting screening tool), T1 (after approximately 2 years), and T2 (in proximity of the peak skeletal growth). Apnea-hypopnea and oxygen desaturations were significantly higher in the study group at T0 and T1 compared with control children. At T2, the values were not significant (p value 0.442 for both apnea-hypopnea index (AHI) and oxygen desaturation index (ODI)). Horizontal airway dimensions were significantly reduced, and vertical airway values were significantly increased in Marfan's syndrome at T0 and T1 but not at T2 (p values at T2: 0.071 for Phw1-Psp, 0.106 for Phw1-Psp', 0.101 for Phw2-Tb, 0.559 for UAL in male and 0.560 for UAL in female). Early rapid maxillary expansion and mandibular advancement using Propulsor Universal Light appliance significantly improved airway patency of Marfan's syndrome children and are strongly encouraged as a routine treatment for both correction of class II malocclusions and prevention of obstructive sleep apnea.

  5. Complete Maxillary Crossbite Correction with a Rapid Palatal Expansion in Mixed Dentition Followed by a Corrective Orthodontic Treatment

    Directory of Open Access Journals (Sweden)

    Orlando Motohiro Tanaka

    2016-01-01

    Full Text Available This case report presents the interceptive orthodontic treatment of a boy, aged 8 years 4 months with a Class I malocclusion with severe transverse maxillary deficiency and complete maxillary crossbite and correction using Haas expansion and fixed appliance. The treatment goals were to correct the posterior crossbite and anterior crossbite and restore the normality of the dentition and occlusion. In phase I, the patient was treated with a modified Haas-type palatal expander, which provided a clinically significant palatal expansion and increased the maxillary arch perimeter with favorable conditions for orthodontic treatment with fixed appliances in phase II. The optimization of E-space and the use of intermaxillary Class III elastics helped to maintain the mandibular incisors upright. A removable wraparound type appliance and a bonded lingual canine-to-canine retainer were used as retention. Although the literature has reported a high rate of relapse after palatal expansion, after 2 years 9 months of posttreatment follow-up, the occlusal result was stable and no skeletal reversals could be detected.

  6. Alterações no volume nasal de pacientes submetidos a disjunção da maxila Changes in nasal volume of patients undergoing rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Renata da Fonseca Lacerda e Muniz

    2008-02-01

    Full Text Available Os efeitos da disjunção maxilar na resistência nasal e fluxo aéreo têm sido amplamente discutidos na literatura, com controvérsias. Suas indicações esqueléticas e dentárias parecem estar bem claras. Porém, aquelas puramente rinológicas não são justificadas, porque nem sempre resultados positivos são encontrados. Este estudo teve por finalidade avaliar a repercussão da disjunção maxilar ortopédica no aspecto respiratório e rinológico dos pacientes submetidos a esse procedimento.Rapid maxillary expansion effects on airflow and nasal resistance has been amply discussed in literature, with controversies. Its skeletal and dental indications seem to be clear, however, those sole rhinologic are not justified, because positive results are not always found. This study had as purpose to evaluate the orthopedic rapid maxillary expansion repercussion on respiratory and rhinologic aspects of patients undergoing this procedure.

  7. Comparison of the treatment effects of different rapid maxillary expansion devices on the maxilla and the mandible. Part 1: Evaluation of dentoalveolar changes.

    Science.gov (United States)

    Canan, Selin; Şenışık, Neslihan Ebru

    2017-06-01

    The aim of this study was to compare the dentoalveolar treatment effects of 3 rapid maxillary expansion (RME) appliances, supported by different tissues, on the maxilla and the mandible. Patients were assessed for eligibility, and those who met the requirements and agreed to participate were enrolled in the study. Participants were randomly allocated into 3 groups, depending on the type of expansion. The tooth-borne group (n = 16; ages, 12.63 ± 1.36 years) had RME with a tooth-borne appliance; the bone-borne group (n = 16; ages, 12.92 ± 1.07 years) had RME with a bone-borne appliance; and the hybrid group (n = 15; ages, 13.41 ± 0.88 years) had RME with hybrid appliances. Dentoalveolar effects were evaluated by digitally superimposed 3-dimensional scans of maxillary dental casts on a coordinate system and linear interdental width measurements of mandibular dental casts in the pretreatment, posttreatment, and postretention periods. For intragroup and intergroup comparisons, 1-way analysis of variance for repeated measures and multivariate analysis of variance were performed, respectively. Similar dentoalveolar treatment effects were achieved in all groups with the exception of a small amount of expansion on the right side in the bone-borne group. All 3 expanders led to the expansion of maxillary dentoalveolar structures with mild relapse. However, the amount of expansion of the bone-borne expander on the right side was statistically lower. Spontaneous interdental expansion was observed in the mandibular dentitions in all groups. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  8. Orthopedic treatment of Class III malocclusion with rapid maxillary expansion combined with a face mask: a cephalometric assessment of craniofacial growth patterns

    Directory of Open Access Journals (Sweden)

    Daniella Torres Tagawa

    2012-06-01

    Full Text Available OBJECTIVE: The aim of this prospective study was to assess potential changes in the cephalometric craniofacial growth pattern of 17 children presenting Angle Class III malocclusion treated with a Haas-type expander combined with a face mask. METHODS: Lateral cephalometric radiographs were taken at beginning (T1 and immediately after removal of the appliances (T2, average of 11 months of treatment. Linear and angular measurements were used to evaluate the cranial base, dentoskeletal changes and facial growth pattern. RESULTS: The length of the anterior cranial base experienced a reduction while the posterior cranial base assumed a more vertical position at T1. Some maxillary movement occurred, there was no rotation of the palatal plane, there was a slight clockwise rotation of the mandible, although not significant. The ANB angle increased, thereby improving the relationship between the jaws; dentoalveolar compensation was more evident in the lower incisors. Five out of 12 cases (29.41% showed the following changes: In one case the pattern became more horizontal and in four cases more vertical. CONCLUSIONS: It was concluded after a short-term assessment that treatment with rapid maxillary expansion (RME associated with a face mask was effective in the correction of Class III malocclusion despite the changes in facial growth pattern observed in a few cases.

  9. Tongue posture improvement and pharyngeal airway enlargement as secondary effects of rapid maxillary expansion: a cone-beam computed tomography study.

    Science.gov (United States)

    Iwasaki, Tomonori; Saitoh, Issei; Takemoto, Yoshihiko; Inada, Emi; Kakuno, Eriko; Kanomi, Ryuzo; Hayasaki, Haruaki; Yamasaki, Youichi

    2013-02-01

    Rapid maxillary expansion (RME) is known to improve nasal airway ventilation. Recent evidence suggests that RME is an effective treatment for obstructive sleep apnea in children with maxillary constriction. However, the effect of RME on tongue posture and pharyngeal airway volume in children with nasal airway obstruction is not clear. In this study, we evaluated these effects using cone-beam computed tomography. Twenty-eight treatment subjects (mean age 9.96 ± 1.21 years) who required RME treatment had cone-beam computed tomography images taken before and after RME. Twenty control subjects (mean age 9.68 ± 1.02 years) received regular orthodontic treatment. Nasal airway ventilation was analyzed by using computational fluid dynamics, and intraoral airway (the low tongue space between tongue and palate) and pharyngeal airway volumes were measured. Intraoral airway volume decreased significantly in the RME group from 1212.9 ± 1370.9 mm(3) before RME to 279.7 ± 472.0 mm(3) after RME. Nasal airway ventilation was significantly correlated with intraoral airway volume. The increase of pharyngeal airway volume in the control group (1226.3 ± 1782.5 mm(3)) was only 41% that of the RME group (3015.4 ± 1297.6 mm(3)). In children with nasal obstruction, RME not only reduces nasal obstruction but also raises tongue posture and enlarges the pharyngeal airway. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  10. Rapid preparation of functional polysaccharides from Pyropia yezoensis by microwave-assistant rapid enzyme digest system.

    Science.gov (United States)

    Lee, Ji-Hyeok; Kim, Hyung-Ho; Ko, Ju-Young; Jang, Jun-Ho; Kim, Gwang-Hoon; Lee, Jung-Suck; Nah, Jae-Woon; Jeon, You-Jin

    2016-11-20

    This study describes a simple preparation of functional polysaccharides from Pyropia yezoensis using a microwave-assistant rapid enzyme digest system (MAREDS) with various carbohydrases, and evaluates their antioxidative effects. Polysaccharide hydrolysates were prepared using MAREDS under different hydrolytic conditions of the carbohydrases and microwave powers. Polysaccharides less than 10kDa (Low molecular weight polysaccharides, LMWP, ≤10kDa) were efficiently obtained using an ultrafiltration (molecular weight cut-off of 10kDa). MAREDS increases AMG activation via an increased degree of hydrolysis; the best AMG hydrolysate was prepared using a 10:1 ratio of substrate to enzyme for 2h in MAREDS with 400W. LMWP consisted of galactose (27.3%), glucose (64.5%), and mannose (8.3%) from the AMG hydrolysate had stronger antioxidant effects than the high molecular weight polysaccharides (>10kDa). We rapidly prepared functional LMWPs by using MAREDS with carbohydrases, and suggest that LMWP might be potentially a valuable algal polysaccharide antioxidant. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Retração rápida de caninos associada ao levantamento do seio maxilar Rapid canine retraction associated with maxillary sinus lifting

    Directory of Open Access Journals (Sweden)

    Paulo Renato Carvalho Ribeiro

    2007-10-01

    Full Text Available INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de 2 ou 3 semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. A técnica cirúrgica para realização deste procedimento é relativamente simples, entretanto, nos casos onde o seio maxilar apresenta-se próximo ao ápice radicular de caninos e pré-molares, sempre há o risco de perfuração da membrana desta cavidade. OBJETIVO: o objetivo deste artigo é apresentar, através de um caso clínico, uma modificação na técnica original proposta por Liou e Huang, onde o levantamento do seio maxilar, executado de forma bastante simples, imprimiu maior controle e segurança ao ato cirúrgico necessário para a realização da retração rápida de caninos. CONCLUSÃO: a retração rápida de caninos é um procedimento exeqüível e o levantamento de seio maxilar pode auxiliar na execução do movimento dentário.INTRODUCTION: Rapid canine distalization using distraction of the periodontal ligament is a tooth movement technique that allows to close the space of extraction of first premolars in about 2 or 3 weeks, reducing orthodontic treatment time considerably. The surgical technique for this procedure is reasonably simple, however, during surgery in the maxilla, always exists the risk of sinus injury when the sinus membrane is close to the apex of canines and first premolars. AIM: The aim of this study is to present a case report showing a modification of the original technique proposed by Liou and Huang, where the maxillary sinus membrane lifting procedure was undertaken in a simple way, leaving it intact, and permitting a safer and more controlled protocol to start the rapid canine retraction. CONCLUSION: Rapid canine retraction is a viable procedure and maxillary sinus lifting may be

  12. Dental arch response to Haas-type rapid maxillary expansion anchored to deciduous vs permanent molars: A multicentric randomized controlled trial.

    Science.gov (United States)

    Ugolini, Alessandro; Cerruto, Carmen; Di Vece, Luca; Ghislanzoni, Luis Huanca; Sforza, Chiarella; Doldo, Tiziana; Silvestrini-Biavati, Armando; Caprioglio, Alberto

    2015-07-01

    To assess maxilla and mandibular arch widths' response to Haas-type rapid maxillary expansion (RME) anchored to deciduous vs permanent molars on children with unilateral posterior crossbite. Seventy patients with unilateral posterior crossbite recruited at the Universities of Genova, Siena, and Insubria (Varese) were randomly located into GrE (RME on second deciduous molars) or Gr6 (RME on first permanent molars) and compared. Upper intermolar distance and permanent molar angulation increased significantly in Gr6 vs GrE at T1. Upper intercanine distance increased significantly in GrE vs Gr6 at T1 and T2. GrE showed significant increases for upper intermolar and upper intercanine widths. Gr6 showed statistically significant increases for upper intermolar widths, for upper and lower intercanine widths, and for increases of angulation of upper and lower permanent molars. GrE showed reduced molar angulation increases at T1 and reduced molar angulation decreases at T2 when compared with Gr6. At T2, the net increase of the upper intercanine distance in GrE was still significant compared with Gr6, indicating a more stable expansion in the anterior area.

  13. New Statistical Method to Analyze Three-Dimensional Landmark Configurations Obtained with Cone-Beam CT: Basic Features and Clinical Application for Rapid Maxillary Expansion

    Energy Technology Data Exchange (ETDEWEB)

    Gamble, Jennifer; Lagravere, Manuel O.; Major, Paul W.; Heo, Giseon [University of Alberta, Edmonton (Canada)

    2012-03-15

    To describe a statistical method of three-dimensional landmark configuration data and apply it to an orthodontic data set comparing two types of rapid maxillary expansion (RME) treatments. Landmark configurations obtained from cone beam CT scans were used to represent patients in two types (please describe what were two types) of RME groups and a control group over four time points. A method using tools from persistent homology and dimensionality reduction is presented and used to identify variability between the subjects. The analysis was in agreement with previous results using conventional methods, which found significant differences between treatment groups and the control, but no distinction between the types of treatment. Additionally, it was found that second molar eruption varied considerably between the subjects, and this has not been evaluated in previous analyses. This method of analysis allows entire configurations to be considered as a whole, and does not require specific inter-landmark distances or angles to be selected. Sources of variability present themselves, without having to be individually sought after. This method is suggested as an additional tool for the analysis of landmark configuration data.

  14. Alterações na dimensão transversal pela expansão rápida da maxila Transverse dimension alterations using rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Roberto M. A. Lima Filho

    2009-10-01

    Full Text Available As deformidades transversais, que se manifestam tipicamente pela mordida cruzada unilateral ou bilateral, são os problemas esqueléticos que mais sequelas podem causar na região craniofacial. Entretanto, são as deformidades que melhor se adaptam às alterações ortopédicas. A expansão rápida da maxila tornou-se rotina na prática ortodôntica. Embora inicialmente tenha sido utilizada na correção da mordida cruzada posterior, atualmente sua indicação ampliou-se para a expansão indireta do arco inferior, obtenção de espaço para correção de apinhamento dentário, correção axial dos dentes posteriores, melhora na estética do sorriso e auxílio no tratamento de pacientes Classe II. A expansão ortopédica da maxila vem atraindo cada vez mais a atenção da comunidade científica devido, principalmente, à sua aplicação e capacidade de alterar o crescimento craniofacial em diversas situações clínicas. Esse tipo de intervenção ortopédica possui grande utilidade terapêutica, pois sua aplicação em diversas anormalidades apresenta maior versatilidade quando comparada aos aparelhos de modificação de crescimento disponíveis atualmente para o tratamento ortodôntico.Transverse deformities, typically manifested by unilateral or bilateral crossbite, are the skeletal problems that can cause more sequels in the craniofacial region. However, such deformities are the most adaptable to orthopedic changes. Rapid maxillary expansion has become a routine in the orthodontic practice. Even though initially such procedure has been used for correction of posterior crossbite, today it has been applied for indirect expansion of the lower arch, obtaining space for correction of dental crowding, correction of axial inclination of posterior teeth, improvement in the smile aesthetics characteristics and on treatment of Class II patients. Orthopedic maxillary expansion has gained increasing attention of the scientific community due to its

  15. Involvement of the Nonneuronal Cholinergic System in Bone Remodeling in Rat Midpalatal Suture after Rapid Maxillary Expansion

    Directory of Open Access Journals (Sweden)

    Xiaoxia Che

    2016-01-01

    Full Text Available Few studies sought to analyze the expression and function of the nonneuronal acetylcholine system in bone remodeling in vivo due to the lack of suitable models. We established a rat maxilla expansion model in which the midline palatine suture of the rat was rapidly expanded under mechanical force application, inducing tissue remodeling and new bone formation, which could be a suitable model to investigate the role of the nonneuronal acetylcholine system in bone remodeling in vivo. During the expansion, the expression pattern changes of the nonneuronal cholinergic system components and the mRNA levels of OPG/RANKL were detected by immunohistochemistry or real-time PCR. The value of the RANKL/OPG ratio significantly increased after 1 day of expansion, indicating dominant bone resorption induced by the mechanical stimulation; however after 3 days of expansion, the value of the RANKL/OPG ratio significantly decreased, suggesting a dominant role of the subsequent bone formation process. Increasing expression of Ach was detected after 3 days of expansion which indicated that ACh might play a role in bone formation. The mRNA expression levels of other components also showed observable changes during the expansion which confirmed the involvement of the nonneuronal cholinergic system in the process of bone remodeling in vivo. Further researches are still needed to figure out the detailed functions of the nonneuronal cholinergic system and its components.

  16. Involvement of the Nonneuronal Cholinergic System in Bone Remodeling in Rat Midpalatal Suture after Rapid Maxillary Expansion

    Science.gov (United States)

    Guo, Jie; Wang, Lue; Miao, Cong; Ge, Lihua; Tian, Zhenchuan; Wang, Jianhong

    2016-01-01

    Few studies sought to analyze the expression and function of the nonneuronal acetylcholine system in bone remodeling in vivo due to the lack of suitable models. We established a rat maxilla expansion model in which the midline palatine suture of the rat was rapidly expanded under mechanical force application, inducing tissue remodeling and new bone formation, which could be a suitable model to investigate the role of the nonneuronal acetylcholine system in bone remodeling in vivo. During the expansion, the expression pattern changes of the nonneuronal cholinergic system components and the mRNA levels of OPG/RANKL were detected by immunohistochemistry or real-time PCR. The value of the RANKL/OPG ratio significantly increased after 1 day of expansion, indicating dominant bone resorption induced by the mechanical stimulation; however after 3 days of expansion, the value of the RANKL/OPG ratio significantly decreased, suggesting a dominant role of the subsequent bone formation process. Increasing expression of Ach was detected after 3 days of expansion which indicated that ACh might play a role in bone formation. The mRNA expression levels of other components also showed observable changes during the expansion which confirmed the involvement of the nonneuronal cholinergic system in the process of bone remodeling in vivo. Further researches are still needed to figure out the detailed functions of the nonneuronal cholinergic system and its components. PMID:27478838

  17. Flexible composite via rapid titania coating by microwave-assisted ...

    Indian Academy of Sciences (India)

    2017-06-09

    Jun 9, 2017 ... carbon fibre via microwave-assisted hydrothermal synthesis (MHS) and to evaluate its photocatalytic properties. The TiO2 nanoparticles were directly grown on the carbon fibre (CF). Thus, a study comparing the conventional titania coating vs. the MHS were performed. The significant layer interaction as a ...

  18. Maxillary obturator

    Directory of Open Access Journals (Sweden)

    Aruna Jawahirlal Bhandari

    2017-01-01

    Full Text Available Defects in the maxillary jaw can be congenital, developmental, acquired, traumatic or surgical involving the oral cavity and related anatomic structure. Absence or loss of some or all of the soft palate and / or hard palate results in insufficient structure or altered function of the remaining tissues. Defects can cause disruption of articulation and airflow during speech production and also nasal reflux during deglutition. Patients after surgical resection have altered anatomy due to scaring, tissue contracture, lack of bony support and tissue edema. These patients have problem of regurgitation of water and food through nose and difficulty in speech. These changes require the fabrication of prosthesis and also sometimes repeated prosthesis adjustments to confirm to the soft tissue changes. To prevent this and to help the patient in deglutition and speech defects must be restored with prosthesis. In such situation an obturator is designed to close the opening between the residual hard and / or soft palate and the pharynx. The prosthesis provided for these patients are called as obturators. An obturator is a prosthesis which is fabricated for the patients with the palatal defects in the form of cleft lip and palate, oroantral fistula or surgical resection after removable of pathology like tumor or cancer. This review article will highlight on the Prosthetic Rehabilitation of the maxillary defects and the types of obturators.

  19. Avaliação clínica dos procedimentos de expansão cirurgicamente assistida da maxila (ECAM Clinical evaluation of surgically assisted maxillary expansion (SAME

    Directory of Open Access Journals (Sweden)

    Paulo Domingos Ribeiro Jr.

    2006-02-01

    Full Text Available OBJETIVO: avaliação clínica dos procedimentos de expansão cirurgicamente assistida da maxila. METODOLOGIA: foram avaliados 10 pacientes tratados através da expansão ortopédica com auxílio cirúrgico, conhecida como expansão cirurgicamente assistida da maxila (ECAM. Avaliou-se a efetividade deste procedimento cirúrgico no auxílio à expansão transversal da maxila proporcionada através de aparelho do tipo Hyrax, a estabilidade desta expansão, as ocorrências pós-operatórias, a quantidade e qualidade da expansão conseguida e alterações estéticas deste procedimento. RESULTADOS E CONCLUSÕES: concluiu-se, com um acompanhamento a longo prazo, que a ECAM trata-se de um procedimento eficiente, estável, que proporciona mudanças funcionais e pouca alteração estética facial.AIM: clinical evaluation of surgically assisted maxillary expansion. METHODS: the present study evaluated 10 patients who underwent surgically assisted maxillary expansion. The efficacy of the surgical procedure helping transverse maxillary expansion given by the Hyrax, expansion stability, post-operatory discomfort during the activation of the device, the quantity and quality of the expansion achieved, the age of the patients, nasal base alteration, and nasal breathing were analyzed. RESULTS AND CONCLUSIONS: from the results, it was possible to observe that surgically assisted maxillary expansion is an efficient and stable treatment, which offers functional changes and minimal aesthetic alterations.

  20. 78 FR 18725 - Homeless Emergency Assistance and Rapid Transition to Housing: Rural Housing Stability Assistance...

    Science.gov (United States)

    2013-03-27

    ... creates the Rural Housing Stability Assistance program to replace the Rural Homelessness Grant program... histories of homelessness and the highest level of need. DATES: Comment Due Date. May 28, 2013. ADDRESSES... Assistance program which replaces the Rural Homelessness Grant program, a program that was authorized but...

  1. Análise morfológica do arco superior de portadores de fissura labiopalatal submetidos a diferentes protocolos de expansão rápida maxilar: avaliação das alterações maxilares Morphological analysis of the maxillary arch in patients with cleft lip and palate submitted to different protocols of rapid maxillary expansion: maxillary alterations evaluation

    Directory of Open Access Journals (Sweden)

    Maíra Massuia de Souza

    2009-10-01

    transverse dimensions of maxillary dental arches by analysis of the dental casts of 15 patients with complete unilateral cleft lip and palate who presented sagittal and transverse maxillary constriction and were submitted to two distinct protocols of rapid maxillary expansion. METHODS: Seven patients were submitted to rapid maxillary expansion (RME by the conventional activation protocol (Group 1, and the others were treated by the protocol proposed by Liou and Tsai in 2005, with alternated expansion and constriction (Group 2. Both groups were later submitted to maxillary protraction with facial mask. Dental casts were obtained at two periods: before placement of a modified Haas expander (T1 and after 24 weeks of treatment (T2. Transverse distances were measured with a digital caliper to register the distances between first upper premolars (anterior area and first upper molars (posterior area. Data were statistically analyzed by the Student's t test. RESULTS AND CONCLUSION: Both protocols were equally effective, since no differences were observed between the groups as to the transverse increasing achieved.

  2. 78 FR 26559 - Homeless Emergency Assistance and Rapid Transition to Housing: Rural Housing Stability Assistance...

    Science.gov (United States)

    2013-05-07

    ... creates the Rural Housing Stability Assistance program to replace the Rural Homelessness Grant program... definition on what constitutes an occasion of homelessness or homeless occasion. In the CoC interim rule, and... Rural Homelessness Grant program, and consequently regulations were never promulgated. Accordingly, this...

  3. Miniscrew-assisted rapid palatal expansion for managing arch perimeter in an adult patient

    National Research Council Canada - National Science Library

    da Cunha Amanda Carneiro; Lee Hisun; Nojima Lincoln Issamu; Nojima Matilde da Cunha Gonçalves; Lee Kee-Joon

    2017-01-01

    ...: This case report illustrates a 24-year old woman, with maxillary transverse deficiency, upper and lower arches crowding, Class II, division 1, subdivision right relationship, previous upper incisors...

  4. Rinometria acústica em crianças submetidas à disjunção maxilar Acoustic rhinometry in children undergoing a rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Mario Cappellette Jr.

    2006-04-01

    Full Text Available OBJETIVO: este estudo foi realizado na Disciplina de Otorrinolaringologia Pediátrica da Escola Paulista de Medicina - UNIFESP, com o objetivo de verificar o comportamento da disjunção maxilar e sua influência na cavidade nasal em crianças de 7 a 8 anos de idade submetidas à rinometria acústica. METODOLOGIA: foram avaliadas 20 crianças respiradoras bucais, portadoras de atresia maxilar diagnosticada clinicamente e submetidas à avaliação objetiva da cavidade nasal pré-disjunção maxilar e pós-disjunção maxilar por meio de rinometria acústica, analisando-se os resultados das áreas transversais mínimas (MCA1 e MCA2 e volumes nasais (VOL1 e VOL2. RESULTADOS: os resultados de MCA1 e MCA2 pré-disjunção maxilar apresentaram-se menores que os valores de MCA1 e MCA2 pós-disjunção maxilar do lado esquerdo; à direita, a MCA1 pré-disjunção maxilar mostrou-se menor que a MCA1 pós-disjunção maxilar, aumentos estes estatisticamente significantes, já os VOL1 e VOL2 pré-disjunção foram menores que o VOL1 e VOL2 pós-disjunção maxilar em ambos os lados, ou seja, os resultados desta diferença foram estatisticamente significantes. CONCLUSÃO: a rinometria acústica é um método objetivo para avaliar a variação da cavidade nasal. A disjunção maxilar promove um aumento significante da área e volume da cavidade nasal.AIM: this research study was carried out by professionals of the Paulista School of Medicine - UNIFESP and it relates to the Pediatric Otorhinolaryngology subject. The current study aimed at checking the behaviour of the maxillary dysjunction and its influence in the nasal cavity of children between 7 and 8 years of age who underwent acoustic rhinometry. METHODS: 20 mouth-breathing subjects presenting maxillary atresia diagnosed clinically were evaluated. Subjects underwent objective evaluation of the nasal cavity before and after maxillary dysjunction by means of acoustic rhinometry. Results of the minimal

  5. Protocols for Late Maxillary Protraction in Cleft Lip and Palate Patients at Childrens Hospital Los Angeles

    Science.gov (United States)

    Yen, Stephen L-K

    2011-01-01

    This paper describes the protocols used at Childrens Hospital Los Angeles (CHLA) to protract the maxilla during early adolescence. It is a modification of techniques introduced by Eric Liou with his Alternate Rapid Maxillary Expansion and Constriction (ALT-RAMEC) technique. The main differences between the CHLA protocol and previous maxillary protraction protocols are the age the protraction is attempted, the sutural loosening by alternating weekly expansion with constriction and the use of Class III elastics to support and redirect the protraction by nightly facemask wear. The CHLA protocol entirely depends on patient compliance and must be carefully taught and monitored. In a cooperative patient, the technique can correct a Class III malocclusion that previously would have been treated with LeFort 1 maxillary advancement surgery. Thus, it is not appropriate for patients requiring 2 jaw surgeries to correct mandibular prognathism, occlusal cants or facial asymmetry. The maxillary protraction appears to work by a combination of skeletal advancement, dental compensation and rotation of the occlusal planes. Microscrew/microimplant/temporary anchorage devices have been used with these maxillary protraction protocols to assist in expanding the maxilla, increasing skeletal anchorage during protraction, limiting dental compensations and reducing skeletal relapse. PMID:21765629

  6. [Maxillary sinus hypoplasia].

    Science.gov (United States)

    Plaza, G; Ferrando, J; Martel, J; Toledano, A; de los Santos, G

    2001-03-01

    Maxillary sinus hypoplasia is rare, with an estimated prevalence of 1-5%. Out of the CT scans performed in sinusal patients between March 1998 and June 1999, we report on 4 isolated maxillary sinus hypoplasia, 4 maxillary sinus hypoplasia associated to concha bullosa, and 10 isolated conchae bullosas. All cases were evaluated by nasosinusal endoscopy and CT scan. Size, location and uni/bilateral presentation of concha bullosa is correlated to maxillary sinus hypoplasia presence, specially with regards to uncinate process presence, medial or lateral retraction. The pathogenesis of maxillary sinus hypoplasia is reviewed, and its relation to concha bullosa, evaluating how this could explain some cases of the so called chronic maxillary sinus atelectasia, as an acquired and progressive variant of maxillary sinus hypoplasia in adults.

  7. Estudo radiográfico digital indireto do efeito da expansão de maxila cirurgicamente assistida (EMCA sobre o septo nasal Indirect digital radiographic study about the effect of surgically assisted maxillary expansion (SAME on the nasal septum

    Directory of Open Access Journals (Sweden)

    Eduardo Sanches Gonçales

    2007-10-01

    maxillary expansion is achieved by means of surgical-orthodontic procedures (known as surgically assisted maxillary expansion - SAME that can cause some effects on the nasal cavity and septum. AIM: To evaluate the behavior of the nasal septum after the procedures of SAME. METHODS: Post-anterior cephalometric and maxillary occlusal radiographs, taken by conventional technique and therefore digitalized, were analyzed from 16 patients undergone SAME. For all patients, the SAME technique consisted of subtotal Le Fort I osteotomy. The radiographs were taken before the surgical procedure, right after (mediate post-operatory time or after the expansion, and thereafter digitalized and measured using DIGORA program. Also, the distances between teeth (canines, first premolars, second premolars, first molars and second molars were registered. RESULTS: The statistical treatment showed an increase in interdental and intermaxillary distances, along with an increase in the width of the base of piriform aperture and in the distances between the base of lateral wall of the piriform aperture and nasal septum. CONCLUSION: SAME is an efficient procedure that seems not to influence the septum position.

  8. Rapid selective metal patterning on polydimethylsiloxane (PDMS) fabricated by capillarity-assisted laser direct write

    KAUST Repository

    Lee, Ming-Tsang

    2011-08-12

    In this study we demonstrate a novel approach for the rapid fabricating micro scale metal (silver) patterning directly on a polydimethylsiloxane (PDMS) substrate. Silver nanoparticles were sintered on PDMS to form conductive metal films using laser direct write (LDW) technology. To achieve good metal film quality, a capillarity-assisted laser direct writing (CALDW) of nanoparticle suspensions on a low surface energy material (PDMS) was utilized. Experimental results showed controllable electrical conductivities and good film properties of the sintered silver patterns. This study reveals an advanced method of metal patterning on PDMS, and proposes a new research application of LDW in a nanoparticle colloidal environment. © 2011 IOP Publishing Ltd.

  9. Rapid microwave-assisted preparation of binary and ternary transition metal sulfide compounds

    Energy Technology Data Exchange (ETDEWEB)

    Butala, Megan M.; Perez, Minue A.; Arnon, Shiri; Göbel, Claudia; Preefer, Molleigh B.; Seshadri, Ram

    2017-12-01

    Transition metal chalcogenides are of interest for energy applications, including energy generation in photoelectrochemical cells and as electrodes for next-generation electrochemical energy storage. Synthetic routes for such chalcogenides typically involve extended heating at elevated temperatures for multiple weeks. We demonstrate here the feasibility of rapidly preparing select sulfide compounds in a matter of minutes, rather than weeks, using microwave-assisted heating in domestic microwaves. We report the preparations of phase pure FeS2, CoS2, and solid solutions thereof from the elements with only 40 min of heating. Conventional furnace and rapid microwave preparations of CuTi2S4 both result in a majority of the targeted phase, even with the significantly shorter heating time of 40 min for microwave methods relative to 12 days using a conventional furnace. The preparations we describe for these compounds can be extended to related structures and chemistries and thus enable rapid screening of the properties and performance of various compositions of interest for electronic, optical, and electrochemical applications.

  10. Avaliação da expansão rápida da maxila por meio da tomografia computadorizada: relato de um caso Computed tomography evaluation of rapid maxillary expansion: a case report

    Directory of Open Access Journals (Sweden)

    Daniela Gamba Garib

    2005-08-01

    Full Text Available Este trabalho descreve os efeitos dentoesqueléticos e periodontais da expansão rápida da maxila (ERM, avaliados por meio da tomografia computadorizada (TC, em uma jovem de 11,6 anos de idade com má oclusão de Classe I e mordida cruzada posterior unilateral funcional. Durante a fase ativa da ERM, o expansor dentossuportado com parafuso Hyrax foi ativado 7mm. A paciente submeteu-se ao exame de TC helicoidal, antes da expansão e após a remoção do aparelho expansor, findo o período de três meses de contenção. Realizaram-se cortes axiais, de um milímetro de espessura, paralelamente ao plano palatino, englobando as regiões dentoalveolar e basal da maxila, até o terço inferior da cavidade nasal. Utilizando-se o recurso de reconstruções multiplanares, mensuraram-se pelo método computadorizado: as dimensões transversas maxilares, a inclinação dos dentes posteriores, a espessura das tábuas ósseas vestibular e lingual, e o nível da crista óssea alveolar vestibular. A expansão rápida da maaxila ocasionou um significante aumento transverso em todas as regiões aferidas, com magnitude decrescente do arco dentário para a base óssea. Os dentes posteriores foram movimentados para vestibular, com um componente de inclinação e translação associados. Tal efeito ortodôntico ocasionou uma redução na espessura da tábua óssea vestibular, e um concomitante aumento na espessura da tábua óssea lingual. Após a expansão, observou-se o desenvolvimento de deiscências ósseas por vestibular dos dentes de ancoragem.This paper presents a computed tomography (CT evaluation of rapid maxillary expansion dentoskeletal and periodontal effects, in a 11.6 year-old girl presenting Class I malocclusion with posterior unilateral crossbite. The tooth-borne expander with Hyrax screw was activated 7-mm. The patient was submitted to helicoidal CT scan before expansion and after the three-month retention period when the expander was removed. Axial

  11. Computer-assisted preoperative simulation for positioning and fixation of plate in 2-stage procedure combining maxillary advancement by distraction technique and mandibular setback surgery

    Directory of Open Access Journals (Sweden)

    Hideyuki Suenaga

    2016-01-01

    Conclusion: The implementation of the computer-assisted preoperative simulation for the positioning and fixation of plate in 2-stage orthognathic procedure using distraction technique and mandibular setback surgery yielded good results.

  12. Rapid microwave-assisted growth of silver nanoparticles on 3D graphene networks for supercapacitor application.

    Science.gov (United States)

    Khamlich, S; Khamliche, T; Dhlamini, M S; Khenfouch, M; Mothudi, B M; Maaza, M

    2017-05-01

    Silver nanoparticles (AgNPs) grown on a three dimensional (3d) graphene networks (GNs) has been successfully prepared by an efficient and rapid microwave-assisted growth process to form GNs/AgNPs nanocomposite electrode materials for supercapacitor application. The 3d nature of the used GNs offers a unique architecture, which creates an efficient conduction networks and maximum utilization of space and interface, and acts as a conductive layer for the deposited AgNPs. The electrochemical performances of the fabricated electrode were evaluated by cyclic voltammetry (CV), galvanostatic charge/discharge and electrochemical impedance spectroscopy (EIS) tests. Specifically, the optimal GNs/AgNPs nanocomposite exhibits remarkable performances with a high specific capacitance of 528Fg-1 at a current density of 1Ag-1 and excellent capacitance retention of ∼93% after 3000cycles. Moreover, this microwave-assisted growth strategy of AgNPs is simple and effective, which could be extended to the construction of other three dimensional graphene based metallic composites for energy storage and conversion applications. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Rapid microwave-assisted synthesis of dextran-coated iron oxide nanoparticles for magnetic resonance imaging

    Science.gov (United States)

    Osborne, Elizabeth A.; Atkins, Tonya M.; Gilbert, Dustin A.; Kauzlarich, Susan M.; Liu, Kai; Louie, Angelique Y.

    2012-06-01

    Currently, magnetic iron oxide nanoparticles are the only nanosized magnetic resonance imaging (MRI) contrast agents approved for clinical use, yet commercial manufacturing of these agents has been limited or discontinued. Though there is still widespread demand for these particles both for clinical use and research, they are difficult to obtain commercially, and complicated syntheses make in-house preparation unfeasible for most biological research labs or clinics. To make commercial production viable and increase accessibility of these products, it is crucial to develop simple, rapid and reproducible preparations of biocompatible iron oxide nanoparticles. Here, we report a rapid, straightforward microwave-assisted synthesis of superparamagnetic dextran-coated iron oxide nanoparticles. The nanoparticles were produced in two hydrodynamic sizes with differing core morphologies by varying the synthetic method as either a two-step or single-step process. A striking benefit of these methods is the ability to obtain swift and consistent results without the necessity for air-, pH- or temperature-sensitive techniques; therefore, reaction times and complex manufacturing processes are greatly reduced as compared to conventional synthetic methods. This is a great benefit for cost-effective translation to commercial production. The nanoparticles are found to be superparamagnetic and exhibit properties consistent for use in MRI. In addition, the dextran coating imparts the water solubility and biocompatibility necessary for in vivo utilization.

  14. Avaliação cefalométrica das alterações verticais e anteroposteriores associadas ao uso do expansor maxilar com cobertura oclusal Cephalometric evaluation of vertical and anteroposterior changes associated with the use of bonded rapid maxillary expansion appliance

    Directory of Open Access Journals (Sweden)

    Moara De Rossi

    2010-06-01

    Full Text Available INTRODUÇÃO: os aparelhos expansores maxilares com cobertura oclusal têm sido sugeridos para controlar o aumento na dimensão vertical da face após a expansão rápida da maxila, porém ainda não há um consenso na literatura sobre seus reais efeitos. OBJETIVO: o objetivo deste trabalho foi avaliar as alterações cefalométricas verticais e anteroposteriores associadas à expansão da maxila realizada com o aparelho expansor com cobertura oclusal. MÉTODOS: a amostra foi composta por 25 crianças, de ambos os gêneros, com idades entre 6 e 10 anos, portadoras de mordida cruzada posterior esquelética. Após a expansão maxilar, o próprio aparelho expansor foi utilizado como contenção fixa. Foram analisadas telerradiografias em norma lateral tomadas antes do início do tratamento e após a remoção do aparelho expansor. CONCLUSÃO: com base nos resultados, pôde-se concluir que o uso do aparelho expansor com cobertura oclusal não alterou significativamente as medidas cefalométricas verticais e anteroposteriores das crianças.INTRODUCTION: Bonded rapid maxillary expansion appliances have been suggested to control increases in the vertical dimension of the face after rapid maxillary expansion but there is still no consensus in the literature concerning its actual effectiveness. OBJECTIVE: The purpose of this study was to evaluate the vertical and anteroposterior cephalometric changes associated with maxillary expansion performed using bonded rapid maxillary expansion appliances. METHODS: The sample consisted of 25 children of both genders, aged between 6 and 10 years old, with skeletal posterior crossbite. After maxillary expansion, the expansion appliance itself was used for fixed retention. Were analyzed lateral teleradiographs taken prior to treatment onset and after removal of the expansion appliance. CONCLUSION: Based on the results, it can be concluded that the use of bonded rapid maxillary expansion appliance did not significantly

  15. Maxillary bone myxoma.

    Science.gov (United States)

    Zainine, R; Mizouni, H; El Korbi, A; Beltaief, N; Sahtout, S; Besbes, G

    2014-09-01

    Maxillary bone myxoma is a rare benign mesenchymal tumor, slow-growing but locally aggressive. Pathogenesis remains disputed. To study the clinical, radiological and histological features and treatment of maxillary myxoma, based on a pediatric case report. An infant of two and a half months presented with endonasal tumor extending to ethmoid. Surgical excision was performed on an endonasal approach. Myxoma was diagnosed by histologic examination of the surgical specimen, whereas initial biopsy had suggested fibrous dysplasia. No recurrence was observed after two and a half years' surveillance. Positive diagnosis of maxillary myxoma is histological. Treatment is primarily surgical. Strict long-term surveillance is required because of the high risk of recurrence. Copyright © 2013. Published by Elsevier Masson SAS.

  16. Bone density of the midpalatal suture 7 months after surgically assisted rapid palatal expansion in adults.

    Science.gov (United States)

    Petrick, Silvia; Hothan, Thorsten; Hietschold, Volker; Schneider, Matthias; Harzer, Winfried; Tausche, Eve

    2011-04-01

    The aims of this study were to analyze changes in bone density of the midpalatal suture after surgically assisted rapid palatal expansion (SARPE) with the bone-borne Dresden Distractor (DD; ITU, Dresden, Germany) via computed tomography (CT) and to compare of preoperative surgical findings with a control group. Sixteen adult patients (mean age 24.5 years) underwent axial CT scans before and 7 months after SARPE. CT image fusion was performed for the midpalatal suture bone. Sixty-six controls (mean age 25.7 years) served for comparing age-related bone density. Bone structure and density were assessed in the coronal plane at the anterior, median, and posterior levels. Highest density was found in the posterior part (1046 Hounsfield units [HU]) before expansion. Seven months after SARPE, bone density was 48% (anterior), 53% (median), and 75% (posterior) compared with preoperative values. The control group showed fairly equal Hounsfield units (889 HU to 900 HU) in all parts. Seven months after SARPE, the midpalatal suture's density achieves just one half to three quarters of the pretreatment values. To maintain the resistance against forces from the unsplit posterior part, the retention time should be lengthened. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  17. Rapid Photodegradation of Methyl Orange (MO Assisted with Cu(II and Tartaric Acid.

    Directory of Open Access Journals (Sweden)

    Jing Guo

    Full Text Available Cu(II and organic carboxylic acids, existing extensively in soil and aquatic environments, can form complexes that may play an important role in the photodegradation of organic contaminants. In this paper, the catalytic role of Cu(II in the removal of methyl orange (MO in the presence of tartaric acid with light was investigated through batch experiments. The results demonstrate that the introduction of Cu(II could markedly enhance the photodegradation of MO. In addition, high initial concentrations of Cu(II and tartaric acid benefited the decomposition of MO. The most rapid removal of MO assisted by Cu(II was achieved at pH 3. The formation of Cu(II-tartaric acid complexes was assumed to be the key factor, generating hydroxyl radicals (•OH and other oxidizing free radicals under irradiation through a ligand-to-metal charge-transfer pathway that was responsible for the efficient degradation of MO. Some intermediates in the reaction system were also detected to support this reaction mechanism.

  18. A rapid microwave-assisted solvothermal approach to lower-valent transition metal oxides.

    Science.gov (United States)

    Moorhead-Rosenberg, Zachary; Harrison, Katharine L; Turner, Travis; Manthiram, Arumugam

    2013-11-18

    A green, rapid microwave-assisted solvothermal process using tetraethylene glycol (TEG) as a reducing agent has been explored as a soft-chemistry route for the preparation of various lower-valent transition metal oxides. To demonstrate the feasibility of the approach, lower-valent binary oxides such as V4O9, Mn3O4 or MnO, CoO, and Cu2O have been obtained within a short reaction time of 30 min by reducing, respectively, V2O5, MnO2, Co3O4, and CuO with TEG at LaCoO3, LaNiO3, and La4Ni3O10. The oxidation state of the transition metal ions and the oxygen content in these ternary oxides could be tuned by precisely controlling the reaction temperatures from 160 to 300 °C. The products have been characterized by X-ray powder diffraction and iodometric titration. The versatility of this novel technique is demonstrated by the facile synthesis of V4O9, which has only been produced recently in single-phase form.

  19. Microwave-assisted chemical insertion: a rapid technique for screening cathodes for Mg-ion batteries

    Energy Technology Data Exchange (ETDEWEB)

    Kaveevivitchai, Watchareeya; Huq, Ashfia; Manthiram, Arumugam

    2016-12-19

    We report an ultrafast microwave-assisted solvothermal method for chemical insertion of Mg2+ ions into host materials using magnesium acetate [Mg(CH3COO)2] as a metal-ion source and diethylene glycol (DEG) as a reducing agent. For instance, up to 3 Mg ions per formula unit of a microporous host framework Mo2.5+yVO9+z could be inserted in as little as 30 min at 170–195 °C in air. This process is superior to the traditional method which involves the use of organometallic reagents, such as di-n-butylmagnesium [(C4H9)2Mg] and magnesium bis(2,6-di-tert-butylphenoxide) [Mg-(O-2,6-But2C6H3)2], and requires an inert atmosphere with extremely long reaction times. Considering the lack of robust electrolytes for Mg-ion batteries, this facile approach can be readily used as a rapid screening technique to identify potential Mg-ion electrode hosts without the necessity of fabricating electrodes and assembling electrochemical cells. Due to the mild reaction conditions, the overall structure and morphology of the Mg-ion inserted products are maintained and the compounds can be used successfully as a cathode in Mg-ion batteries. The combined synchrotron X-ray and neutron diffraction Rietveld analysis reveals the structure of the Mg-inserted compounds and gives an insight into the interactions between the Mg ions and the open-tunnel host framework.

  20. [Rapid maxillary expansion: clinical and radiographic principles].

    Science.gov (United States)

    dos Santos-Pinto, C C; Henriques, J F

    1990-01-01

    The midpalatine suture disjunction as an auxiliary means in the treatment of malocclusions with horizontal craneal base deficiencies has become a routine procedure in the orthodontic clinic. Therefore, for it to become an adequate therapeutical procedure for our patients it is of upmost importance we make a radiographic examinative so that we may juntify our diagnosis in that refers to facial skeletal disharmonies, specially in horizontal maxilary discrepancies.

  1. Maxillary sinus augmentation

    Directory of Open Access Journals (Sweden)

    A B Tarun Kumar

    2015-01-01

    Full Text Available Placing dental implants in the maxillary posterior region can be both challenging and un-nerving for a regular implant dentist who is not well versed with advanced surgical procedures. It is vital for a general dentist to understand the fundamentals of bone grafting the maxillary sinus if he/she is really committed to providing the best health care for their patients. The dental practice is seeing an increasing group of patients who are living longer, and this group of older baby boomers often has an edentulous posterior maxilla either unilateral or bilateral. When edentulous, the posterior maxilla more likely has diminished bone height, which does not allow for the placement of dental implants without creating additional bone. Through grafting the maxillary sinus, bone of ideal quality can be created (allowing for placement of dental implants, which offer many advantages over other tooth replacement modalities. The sinus graft offers the dental patient a predictable procedure of regenerating lost osseous structure in the posterior maxilla. This offers the patient many advantages for long-term success. If dentists understand these concepts, they can better educate their patients and guide them to have the procedure performed. This article outlines bone grafting of the maxillary sinus for the purpose of placing dental implants. This review will help the readers to understand the intricacies of sinus augmentation. They can relate their patient's condition with the available literature and chalk out the best treatment plan for the patient, especially by using indirect sinus augmentation procedures which are less invasive and highly successful if done using prescribed technique.

  2. [Maxillary bone sarcoidosis].

    Science.gov (United States)

    El Fares, N; El Bouihi, M; Zouhair, K; El Kabli, H; Benchikhi, H

    2011-04-01

    Sarcoidosis is an unexplained systemic granulomatosis. Bone localizations of the disease are rare. We report a maxillary localization. A 35-year-old patient consulted for facial dysmorphia first observed 2 years before. This swelling was associated to nodular panniculitis lesions and xerostomia. The facial asymmetry was due to maxillary gingival and alveolar swelling. It was associated with scarring in the legs and a purple nodular facial lesion. Lip and jaw biopsies revealed epithelioid and giant cell granulomas without caseous necrosis. The panoramic dental X-ray showed diffuse horizontal alveolar ridge lysis and CT scan revealed an osteolytic lesion of the right maxilla associated to a bone-condensing lesion of the left hemi-mandible. The diagnosis of sarcoidosis is made in case of epithelioid and giant cell granulomas without caseous necrosis and the ruling out of other possible diagnoses, including tuberculosis. Bone involvement is rare; face and maxillary localization are extremely rare. The recommended treatment is corticosteroids. Facial remodeling surgery is not recommended. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  3. Microwave-assisted rapid extracellular synthesis of stable bio-functionalized silver nanoparticles from guava (Psidium guajava) leaf extract

    Energy Technology Data Exchange (ETDEWEB)

    Raghunandan, Deshpande [H.K.E.S' s College of Pharmacy (India); Mahesh, Bedre D. [Gulbarga University, Materials Chemistry Laboratory, Department of Material Science (India); Basavaraja, S. [Jawaharlal Nehru Centre for Advanced Scientific Research, Veeco-India Nanotechnology Laboratory (India); Balaji, S. D. [Gulbarga University, Materials Chemistry Laboratory, Department of Material Science (India); Manjunath, S. Y. [Sri Krupa, Institute of Pharmaceutical Science (India); Venkataraman, A., E-mail: raman_chem@rediffmail.com [Gulbarga University, Materials Chemistry Laboratory, Department of Material Science (India)

    2011-05-15

    Our research interest centers on microwave-assisted rapid extracellular synthesis of bio-functionalized silver nanoparticles of 26 {+-} 5 nm from guava (Psidium guajava) leaf extract with control over dimension and composition. The reaction occurs very rapidly as the formation of spherical nanoparticles almost completed within 90 s. The probable pathway of the biosynthesis is suggested. Appearance, crystalline nature, size and shape of nanoparticles are understood by UV-vis (UV-vis spectroscopy), FTIR (fourier transform infrared spectroscopy), XRD (X-ray diffraction), FESEM (field emission scanning electron microscopy) and TEM (transmission electron microscopy) techniques. Microwave-assisted route is selected for the synthesis of silver nanoparticles to carry out the reaction fast, suppress the enzymatic action and to keep the process environmentally clean and green.

  4. Microwave-assisted rapid extracellular synthesis of stable bio-functionalized silver nanoparticles from guava ( Psidium guajava) leaf extract

    Science.gov (United States)

    Raghunandan, Deshpande; Mahesh, Bedre D.; Basavaraja, S.; Balaji, S. D.; Manjunath, S. Y.; Venkataraman, A.

    2011-05-01

    Our research interest centers on microwave-assisted rapid extracellular synthesis of bio-functionalized silver nanoparticles of 26 ± 5 nm from guava ( Psidium guajava) leaf extract with control over dimension and composition. The reaction occurs very rapidly as the formation of spherical nanoparticles almost completed within 90 s. The probable pathway of the biosynthesis is suggested. Appearance, crystalline nature, size and shape of nanoparticles are understood by UV-vis (UV-vis spectroscopy), FTIR (fourier transform infrared spectroscopy), XRD (X-ray diffraction), FESEM (field emission scanning electron microscopy) and TEM (transmission electron microscopy) techniques. Microwave-assisted route is selected for the synthesis of silver nanoparticles to carry out the reaction fast, suppress the enzymatic action and to keep the process environmentally clean and green.

  5. Rapid Detection of OXA-48-Producing Enterobacteriaceae by Matrix-Assisted Laser Desorption Ionization−Time of Flight Mass Spectrometry

    Science.gov (United States)

    Oviaño, Marina; Barba, Maria José; Fernández, Begoña; Ortega, Adriana; Aracil, Belén; Oteo, Jesús; Campos, José

    2015-01-01

    A rapid and sensitive (100%) matrix-assisted laser desorption ionization−time of flight mass spectrometry (MALDI-TOF MS) assay was developed to detect OXA-48-type producers, using 161 previously characterized clinical isolates. Ertapenem was monitored to detect carbapenem resistance, and temocillin was included in the assay as a marker for OXA-48-producers. Structural analysis of temocillin is described. Data are obtained within 60 min. PMID:26677247

  6. Previsibilidade de sucesso na disjunção palatina avaliada pelo estágio de maturação esquelética: estudo piloto Sucess predictability in rapid maxillary expansion when assessed by skeletal growth maturation phase: pilot study

    Directory of Open Access Journals (Sweden)

    Rodrigo Rezende de Albuquerque

    2006-04-01

    Full Text Available OBJETIVO: a proposta deste estudo foi determinar se a previsibilidade de sucesso da disjunção palatina está correlacionada a algum evento de maturidade esquelética que determine o final do crescimento geral do organismo. METODOLOGIA: utilizando o conhecimento dos estágios de maturação esquelética visualizados por radiografia de mão e punho e registrados em um gráfico do surto de crescimento puberal, foram avaliados dezenove pacientes de ambos os gêneros, com idades variando de dez anos e três meses a vinte e oito anos e quatro meses, supervisionados por análises clínicas e radiográficas específicas antes e após o procedimento de disjunção palatina. RESULTADO E CONCLUSÃO: pode-se afirmar que não foi possível determinar a previsibilidade de sucesso da disjunção palatina quando esta foi correlacionada com a ossificação total do osso rádio.AIM: to evaluate the possibility of rapid maxillary expansion in patients who have reached the decisive event of facial growth ending (total fusion of the radius. METHODS: the study was held using esqueletal maturation data from hand and wrist x-ray plotted in a puberal growth spurt graph from nineteen patients of both genders at ages ranging from ten years and three months to twenty-eight years and four months surveilled by specific clinical and radiographic analysis before and after the rapid maxillary expansion procedure. RESULTS AND CONCLUSION: it could be concluded that it was not possible to establish a successful correlation between total fusion of radius with rapid maxillary expansion.

  7. Rapid detection of undesired cosmetic ingredients by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Ouyang, Jie; An, Dongli; Chen, Tengteng; Lin, Zhiwei

    2017-10-01

    In recent years, cosmetic industry profits soared due to the widespread use of cosmetics, which resulted in illicit manufacturers and products of poor quality. Therefore, the rapid and accurate detection of the composition of cosmetics has become crucial. At present, numerous methods, such as gas chromatography and liquid chromatography-mass spectrometry, were available for the analysis of cosmetic ingredients. However, these methods present several limitations, such as failure to perform comprehensive and rapid analysis of the samples. Compared with other techniques, matrix-assisted laser desorption ionization time-of-flight mass spectrometry offered the advantages of wide detection range, fast speed and high accuracy. In this article, we briefly summarized how to select a suitable matrix and adjust the appropriate laser energy. We also discussed the rapid identification of undesired ingredients, focusing on antibiotics and hormones in cosmetics.

  8. The effectiveness of non-surgical maxillary expansion: a meta-analysis.

    Science.gov (United States)

    Zhou, Yang; Long, Hu; Ye, Niansong; Xue, Junjie; Yang, Xin; Liao, Lina; Lai, Wenli

    2014-04-01

    To evaluate and compare the effectiveness of rapid maxillary expansion (RME) and slow maxillary expansion (SME). PubMed, Embase, Web of Science, CENTRAL, ProQuest Dissertations & Theses, ClinicalTrial.gov, and SIGLE were searched from January 1980 to October 2012 for randomized or non-randomized controlled trials. The processes of study search, selection, and quality assessment were conducted independently and in duplicate. Original outcome data underwent statistical pooling through Review Manager 5. Fourteen eligible studies were finally included and two interventions (RME and SME) studied. Four outcomes (maxillary intermolar width, maxillary intercanine width, maxillary interpremolar width, and mandibular intermolar width) during three time periods (expansion, retention, and net change) were statistically pooled. The sensitivity analysis revealed that the results from the meta-analysis were generally robust. Egger's test and Begg's test detected no publication bias except for maxillary intercanine width in expansion period for SME versus control. SME is effective in expanding maxillary arch, while we cannot determine its effectiveness in mandibular arch expansion. RME is effective in expanding both maxillary and mandibular arches. Furthermore, SME is superior to RME in expanding molar region of maxillary arch, while similar with RME in mandibular arch expansion. However, we cannot compare their effectiveness in maxillary anterior region.

  9. Congenital maxillary double lip

    Directory of Open Access Journals (Sweden)

    Dinesh Singh Chauhan

    2012-01-01

    Full Text Available Double lip, also referred to as "macrocheilia," is a rare anomaly which affects the upper lip more commonly than the lower lip. It consists of a fold of excess or redundant hypertrophic tissue on the mucosal side of the lip. The congenital double lip is believed to be present at birth and becomes more prominent after eruption of teeth. It affects esthetics and also interferes with speech and mastication. Simple surgical excision produces good functional and cosmetic results. We report a case of a non-syndromic congenital maxillary double lip in a 21-year-old male patient.

  10. Diagnosis and treatment of transverse maxillary deficiency.

    Science.gov (United States)

    Betts, N J; Vanarsdall, R L; Barber, H D; Higgins-Barber, K; Fonseca, R J

    1995-01-01

    Treatment of skeletally mature patients is often complicated by inadequately treated or undiagnosed transverse skeletal discrepancy. This report emphasizes diagnosis of transverse maxillo-mandibular discrepancy and describes recommendations for treatment. Proper treatment strategy must consider the type and magnitude of transverse deficiency, patient's growth status, dentofacial esthetics, stability factors, and periodontal tissue health. Indications for surgically assisted maxillary expansion are listed, and the recommended surgical technique to improve frontal dentofacial esthetics, provide better stability, and enhance long-term periodontal health is described. Specific modifications in surgical technique to help prevent postoperative complications are included. New recommendations for sequencing, timing, and correction of transverse deficiency are presented.

  11. Rapid and convenient semi-automated microwave-assisted solid-phase synthesis of arylopeptoids

    DEFF Research Database (Denmark)

    Rasmussen, Jakob Ewald; Boccia, Marcello Massimo; Nielsen, John

    2014-01-01

    A facile and expedient route to the synthesis of arylopeptoid oligomers (N-alkylated aminomethyl benz-amides) using semi-automated microwave-assisted solid-phase synthesis is presented. The synthesis was optimized for the incorporation of side chains derived from sterically hindered or unreactive...

  12. A expansão rápida da maxila com haas e a fala na fissura labiopalatina transforame Rapid maxillary expansion with Haas and the speech in people with cleft lip and palate

    Directory of Open Access Journals (Sweden)

    Christiane Moraes Lazzari

    2009-01-01

    Full Text Available OBJETIVO: verificar os efeitos da Expansão Rápida da Maxila (ERM, com aparelho Haas, na fala do paciente com fissura labiopalatina (FLP Transforame. MÉTODOS: 12 indivíduos entre sete e 14 anos, sendo seis meninos e seis meninas, divididos em dois grupos. O Grupo 1 (G1, submetido à ERM com protocolo de ativação convencional e, o Grupo 2 (G2, submetido à ERM com protocolo de ativação preconizado por Liou e Tsai (2005 com expansões e constrições alternadas. Realizou-se avaliação da fala, análise acústica com programa Praat e avaliação perceptivo-auditiva por julgadores fonoaudiólogos e leigos. RESULTADOS: a medição dos tempos de emissão das vogais por análise acústica mostrou diferença estatisticamente significante na avaliação pós-ERM da vogal /i/ no G1 e da vogal /a/ no G2. Na avaliação perceptivo-auditiva, não houve diferenças estatisticamente significantes entre os grupos nas avaliações de Nasalidade e Clareza na Articulação, porém, na medida em que os julgadores atribuíram melhora à Nasalidade, também atribuíram melhora à Articulação e, assim também em relação as variáveis "Melhor", "Igual" e "Pior". CONCLUSÃO: a diminuição dos tempos de emissão pós-ERM, indica que o aumento no escape aéreo nasal ocasiona menores tempos de emissão. A análise perceptivo-auditiva mostrou-se um instrumento eficaz de avaliação, havendo concordância entre julgadores leigos e fonoaudiólogos. Essa avaliação indicou também, que na medida em que a nasalidade diminui ocorre maior clareza na articulação.PURPOSE: to check the effects of rapid maxillary expansion (RME with Haas, made by orthodontistic, in speech of the patient with cleft lip and palate. METHODS: 12 subjects, 6 boys and 6 girls, with age between 7 and 14-year old, divided in two groups. Group 1 (G1, was submitted to conventional activation RME protocol and Group 2 (G2, was submitted to activation ERM protocol in accordance with Liou and Tsai

  13. Avaliação do efeito da expansão rápida da maxila na via aérea superior, por meio da nasofibroscopia: descrição da técnica e relato de caso Evaluation of the effect of rapid maxillary expansion on the upper airway using nasofibroscopy: case report and description of the technique

    Directory of Open Access Journals (Sweden)

    Edmilsson Pedro Jorge

    2011-02-01

    Full Text Available A finalidade deste artigo é avaliar o efeito da expansão rápida da maxila (ERM na via aérea superior. Por intermédio de um caso clínico, será relatado como indivíduos com atresia da maxila e com comprometimento da função naso-respiratória podem beneficiar-se com a ERM. Para entender melhor as alterações morfológicas decorrentes do paciente com problemas respiratórios, deve-se conhecer a anatomia e a fisiologia do sistema respiratório. Entretanto, não se pode esquecer que o tratamento deste paciente é multidisciplinar, envolvendo o ortodontista, otorrinolaringologista e a fonoaudióloga.The aim of the present investigation is to evaluate the effect of rapid maxillary expansion (RME on the upper airway. A clinical case is presented to describe how patients with atresic maxilla and reduced naso-respiratory function can have benefits from rapid maxillary expansion. In order to better understand the morphological alterations present in patients with respiratory disorders, it is necessary to understand the respiratory system's anatomy and physiology. However, it is relevant to mention that this patient undergoes a multidisciplinary treatment, involving the orthodontist, the otorhinolaryngologist and the phonoaudiologist.

  14. Wax: A benign hydrogen-storage material that rapidly releases H2-rich gases through microwave-assisted catalytic decomposition.

    Science.gov (United States)

    Gonzalez-Cortes, S; Slocombe, D R; Xiao, T; Aldawsari, A; Yao, B; Kuznetsov, V L; Liberti, E; Kirkland, A I; Alkinani, M S; Al-Megren, H A; Thomas, J M; Edwards, P P

    2016-10-19

    Hydrogen is often described as the fuel of the future, especially for application in hydrogen powered fuel-cell vehicles (HFCV's). However, its widespread implementation in this role has been thwarted by the lack of a lightweight, safe, on-board hydrogen storage material. Here we show that benign, readily-available hydrocarbon wax is capable of rapidly releasing large amounts of hydrogen through microwave-assisted catalytic decomposition. This discovery offers a new material and system for safe and efficient hydrogen storage and could facilitate its application in a HFCV. Importantly, hydrogen storage materials made of wax can be manufactured through completely sustainable processes utilizing biomass or other renewable feedstocks.

  15. [Maxillary sinus myxoma].

    Science.gov (United States)

    Niedzielski, Artur; Partycka-Pietrzyk, Kornela; Brodzisz, Agnieszka; Walczyna, Beata; Mielnik-Niedzielska, Grażyna

    2016-07-29

    Myxoma is a slow growing, benign neoplasm, which pathogenesis still remains disputed. The lesion has well-defined borders but a true capsule is absent. Because of that myxoma can be locally invasive causing bone destruction. A change is mainly observed among persons between 20-30 years of age and is very uncommon in the pediatric population. Most myxomas are observed in myocardium, but rarely may also manifest in the head and neck region. In the paper we describe an unusual case of myxoma of maxillary sinus in a female infant. Diagnostic challenges, treatment, outcome, post-operative follow-up are discussed as well as a review of the literature in order to present many features of this rare pathology. © 2016 MEDPRESS.

  16. 76 FR 75994 - Homeless Emergency Assistance and Rapid Transition to Housing: Defining “Homeless”

    Science.gov (United States)

    2011-12-05

    ... Homelessness Grant program. The HEARTH Act also codifies in law the Continuum of Care planning process, long a... emergency shelter and homelessness prevention activities and to add rapid rehousing activities. The new Rural Housing Stability program replaces the Rural Homelessness Grant program. The HEARTH Act also...

  17. Alterações da cavidade nasal e do padrão respiratório após expansão maxilar Nasal cavity changes and the respiratory standard after maxillary expansion

    Directory of Open Access Journals (Sweden)

    Tatiana Ramires

    2008-10-01

    Full Text Available A deficiência transversal da maxila é uma anomalia dentofacial relacionada à diminuição do diâmetro do arco maxilar. Este tipo de deformidade está muitas vezes associado a deficiência respiratória nasal, sendo um importante fator etiopatogênico. O tratamento desta atresia pode ser realizado através da Expansão Rápida da Maxila ou Expansão Rápida da Maxila Cirurgicamente Assistida, ficando na dependência da idade do paciente. Ambos os procedimentos levarão a mudanças na estrutura craniofacial, especialmente na cavidade nasal. OBJETIVO: Através da descrição de trabalhos levantados na literatura, procurou-se relatar a relação existente entre a expansão maxilar, cavidade nasal e resistência aérea nasal. MÉTODO: Foi realizada uma tradicional revisão assistemática da literatura, utilizando trabalhos do tipo experimentais, incluindo os que utilizaram Expansão Rápida da Maxila e Expansão Rápida da Maxila Cirurgicamente Assistida, e excluindo os que utilizaram Expansão Maxilar por Osteotomia Segmentada para o tratamento da atresia maxilar. RESULTADO: Tanto a Expansão Rápida da Maxila quanto a Expansão Rápida da Maxila Cirurgicamente Assistida levam a mudanças dentofaciais, especialmente sobre a cavidade nasal, causando um aumento da largura nasal, o que pode levar à diminuição da Resistência Aérea Nasal. CONCLUSÃO: Através dos estudos cefalométricos ântero-posteriores, fica evidente o aumento da largura da cavidade nasal após expansão maxilar.Mandibular cross-sectional deficiency is a dentofacial defect in connection with the narrowing of the mandibular arch width. This abnormality is a significant etiopathogenic factor and it is often associated with nasal breathing difficulties. This atresia may be treated through Rapid Maxillary Expansion or Surgically Assisted Rapid Maxillary Expansion, depending on the patient's age. Both procedures will change the craniofacial structure, especially the nasal cavity

  18. Modification of the technique of osteotomy for surgical maxillary expansion

    Directory of Open Access Journals (Sweden)

    João Luis Carlini

    2015-10-01

    Full Text Available Surgically assisted maxillary expansion is a technique used to correct transverse maxillary deficiency, which is a dentofacial anomaly related to the decrease of the upper arch over the lower arch. It is applied to patients in their late teens and adults due to skeletal maturity, causing obliteration of the intermaxillary suture, which requires orthodontic procedure, associated with surgery. The purpose of this study is to report the clinical case of a patient admitted for surgical maxillary expansion through the modified technique and point out the possible advantages, such as aesthetics maintenence, long-term stability, faster return to orthodontic treatment, and improved bone healing. However, there are some contraindications when the patient presents severe crowding, roots of the canine and lateral incisor are converging and in patients who will undergo to protraction with facial mask.

  19. Análise da expansão rápida da maxila por meio da tomografia computadorizada Cone-Beam Analysis of rapid maxillary expansion using Cone-Beam computed tomography

    Directory of Open Access Journals (Sweden)

    Gerson Luiz Ulema Ribeiro

    2010-12-01

    Full Text Available Diante do diagnóstico de uma arcada maxilar esqueleticamente atrésica, o tratamento de escolha geralmente é a expansão ortopédica da maxila, envolvendo a separação da sutura palatina mediana. A avaliação dessa sutura era basicamente realizada por meio da radiografia oclusal superior, limitando sua análise em norma frontal. Da mesma forma, quantificar essa atresia radiograficamente nas telerradiografias cefalométricas sempre foi um obstáculo para o clínico, devido à grande sobreposição das estruturas faciais. O advento da tomografia computadorizada na Odontologia tem transformado a forma de diagnóstico devido à alta precisão na avaliação das dimensões das estruturas faciais, possibilitando quantificar de maneira fiel o comportamento das hemimaxilas, a inclinação dentária, a formação óssea na sutura nos três planos do espaço, assim como a reabsorção óssea alveolar e demais consequências da expansão palatinaWhenever a maxillary arch is diagnosed as skeletally atresic the treatment of choice is usually maxillary orthopedic expansion, involving separation of the midpalatal suture. Basically, this suture used to be assessed with the aid of a maxillary occlusal radiograph, which limited its posteroanterior evaluation. Similarly, quantifying this atresia in cephalometric x-rays always posed an obstacle for clinicians owing to considerable superimposition of facial structures. With the advent of computed tomography, this technology has revolutionized diagnostic methods in dentistry because it provides high dimensional accuracy of the facial structures and a reliable method for quantifying the behavior of the maxillary halves, tooth inclination, bone formation at the suture in the three planes of space, as well as alveolar bone resorption and other consequences of palatal expansion

  20. Laccase-Assisted Rapid Synthesis of Colloidal Gold Nanoparticles for the Catalytic Reduction of 4-Nitrophenol

    OpenAIRE

    Li, Fang; Li, Zheng; Zeng, Chang; Hu, Yonggang

    2017-01-01

    A green method for the rapid preparation of uniform-sized colloidal gold nanoparticles under ambient conditions was presented and validated using laccase as a reduction agent in alkaline medium. UV-Vis spectrophotometry, field-emission high-resolution transmission electron microscopy, X-ray diffraction, selected area electron diffraction, energy dispersive X-ray analysis, zetasizer, and Fourier transform infrared spectroscopy were used to characterize the gold nanoparticles. The gold nanopart...

  1. Rapid identification of bacillus anthracis spores in suspicious powder samples by using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)

    NARCIS (Netherlands)

    Dybwad, M.; Laaken, A.L. van der; Blatny, J.M.; Paauw, A.

    2013-01-01

    Rapid and reliable identification of Bacillus anthracis spores in suspicious powders is important to mitigate the safety risks and economic burdens associated with such incidents. The aim of this study was to develop and validate a rapid and reliable laboratory- based matrix-assisted laser

  2. [The original method for the endonasal surgical access to the maxillary sinus through crista conchalis of the maxillary bone].

    Science.gov (United States)

    Tsarapkin, G Yu; Tovmasyan, A S; Fedotkina, К M; Gorovaya, E V; Arzamazov, S G; Panasov, S A

    The objective of the present work was to develop a technique for the endonasal surgical access to the maxillary sinus through crista conchalis of the maxillary bone and to evaluate the effectiveness and safety of the surgical treatment by this method. A total of 210 patients underwent the CT-assisted examination of the paranasal sinuses. The data obtained made it possible to characterize the detailed anatomical structure of crista conchalis of a maxillary bone that forms the anterior part of the medial wall of the maxillary sinus. The syntopy in relation to the distal end of the nasolacrimal canal and the cavity of the maxillary sinus was investigated. The results of the study were used to develop the original technique for endonasal antrotomy that included the 0.5-1.0 cm long vertical section of the mucous membrane at the level of the anterior end of the inferior turbinated bone approximately 1 mm from the edge of the bone aperture of the nose which exposed crista conchalis up to the place of fixation of the inferior turbinated bone. Then, the diamond drill burr was use to carry out trepanation of the medial wall of the maxillary sinus in the region of crista conchalis of the maxillary bone; sanitation of the of the sinus was followed by the apposition of the edges of the incision and their fixation with two sutures. The safety of the proposed surgical technique was confirmed by results of the repeated CT examinations of the paranasal sinus and its effectiveness by the clinical follow-up observations.

  3. Ball mill assisted rapid mechanochemical extraction method for natural products from plants.

    Science.gov (United States)

    Wang, Man; Bi, Wentao; Huang, Xiaohua; Chen, David Da Yong

    2016-06-03

    A ball mill assisted mechanochemical extraction method was developed to extract compounds of natural product (NP) from plant using ionic liquid (IL). A small volume ball mill, also known as PastPrep(®) Homogenizer, which is often used for high-speed lysis of biological samples and for other applications, was used to dramatically increase the speed, completeness and reproducibility of the extraction process at room temperature to preserve the chemical integrity of the extracted compounds. In this study, tanshinones were selected as target compounds to evaluate the performance of this extraction method. Factors affecting the extraction efficiency, such as the duration, IL concentration and solid/liquid ratio were systematically optimized using the response surface methodology. Under the optimized conditions, the described method was more efficient and much faster than the conventional extraction methods such as methanol based ultrasound assisted extraction (UAE) and heat reflux extraction (HRE) that consumes a lot more organic solvent. In addition, the natural products of interest were enriched by anion metathesis of ionic liquids, combining extraction and preconcentration in the same process. The extractant was analyzed by HPLC and LC-MS. The reproducibility (RSD, n=5), correlation coefficient (r(2)) of the calibration curve, and the limit of detection, were determined to be in the range of 4.7-5.2%, 0.9992-0.9995, and 20-51ng/mL, respectively. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Cone-Beam computed tomography evaluation of maxillary expansion in twins with cleft lip and palate

    OpenAIRE

    Luciane Macedo de Menezes; Fabiane Azeredo; André Weissheimer; Juliana Lindemann Rizzato; Susana Maria Deon Rizzatto

    2012-01-01

    OBJECTIVE: The establishment of normal occlusal relationships in patients with cleft lip and palate using rapid maxillary expansion may promote good conditions for future rehabilitation. OBJECTIVE: This study describes the clinical case of monozygotic twins with unilateral cleft lip and palate at the age of mixed dentition, who were treated using the same rapid maxillary expansion protocol, but with two different screws (conventional and fan-type expansion screw). Results were evaluated using...

  5. Effects of maxillary sinus floor elevation surgery on maxillary sinus physiology

    NARCIS (Netherlands)

    Timmenga, NM; Raghoebar, GM; Liem, RSB; van Weissenbruch, R; Manson, WL; Vissink, A

    In a prospective study, the effects of elevation surgery of the maxillary sinus floor on maxillary sinus physiology were assessed. Seventeen consecutive patients without preoperative anamnestic, clinical and radiological signs of maxillary sinusitis underwent sinus floor elevation surgery with iliac

  6. [CFD-simulation of the air flows in the maxillary sinus].

    Science.gov (United States)

    Shcherbakov, D A; Krukov, A I; Krasnozhen, V N; Garskova, Yu A; Saushin, I I

    This article summarizes the results of computer simulation of the air flows in the nasal cavity and the maxillary sinus by the computational fluid dynamics (CFD) method. The objective of the study was to apply the method of computational aerodynamics to simulate the air flows in the nasal cavity and the maxillary sinus under the normal conditions and after the surgical interventions on the middle nasal meatus. The normal air space of the nasal cavity and paranasal sinuses was simulated and the computer modeling of the main options for the surgical approach to the maxillary sinus through the middle nasal meatus was performed including balloon sinuplasty, functional endoscopic sinus surgery, and uncinate process mobilization. The study has demonstrated the increase of the air flow velocity in the maxillary sinus after computer-assisted balloon sinuplasty. The computer simulation of functional endoscopic sinus surgery including the removal of the uncinated process revealed the mass exchange between the maxillary sinus and the nasal cavity.

  7. Rapid microwave-assisted transesterification of yellow horn oil to biodiesel using a heteropolyacid solid catalyst.

    Science.gov (United States)

    Zhang, Su; Zu, Yuan-Gang; Fu, Yu-Jie; Luo, Meng; Zhang, Dong-Yang; Efferth, Thomas

    2010-02-01

    An efficient microwave-assisted transesterification (MAT) technique was developed to prepare biodiesel from yellow horn (Xanthoceras sorbifolia Bunge.) oil with a heteropolyacid (HPA) catalyst namely Cs(2.5)H(0.5)PW(12)O(40). A study for optimizing the reaction conditions such as reaction temperature, time, molar ratio of methanol/oil, catalyst amount, and recycle number of catalyst has been performed. The maximum yield of fatty acid methyl esters (FAMEs) reached 96.22% under optimal conditions of temperature 60 degrees C, 10 min, molar ratio of methanol/oil 12:1, 1% (w/w of oil) catalyst and minimum recycle number nine times. The final product of biodiesel, obtained after the new catalyzed process, was analyzed by gas chromatography. The results showed that the Cs(2.5)H(0.5)PW(12)O(40) heterogeneous acid catalyst had higher efficiency for transesterification under microwave irradiation compared with the conventional method. The product properties of yellow horn biodiesel are found to be in agreement with EN 14214 standard.

  8. Rapid ablation of dental hard tissue using promoter-assisted pulsed Nd:YAG laser

    Science.gov (United States)

    Frederickson, Christopher J.; Lu, Quiang; Hayes, Donald J.; Wallace, David B.; Grove, Michael E.; Bell, Brent A.; Motamedi, Massoud; Rastegar, Sohi; Wright, C. G.; Arcoria, Charles J.

    1997-05-01

    Nd:YAG lasers have been used previously for selective removal of various material from teeth. To permit ablation of healthy enamel with the Nd:YAG laser, we have adopted a strategy in which micro-drops of photoabsorptive 'promoters' are placed on the enamel to enhance absorption of individual laser pulses. Ink-jet technology dispenses the micro-drops with micron- and millisecond-scale precision. Various promoters using drug and cosmetic dyes, indocyanine green, or carbon-black pigments have been studied. Typical ablation parameters are 1.064 micrometers ; 20-180 mJ per pulse; 100 microsecond(s) ; 10-30 pulses/sec; 0.2-2.0 nl drops. Recent results from the program include: (1) For a variety of promoters, a monotonic relationship obtains between absorption coefficient at 1.064 micrometers and the efficiency of ablation of enamel. (2) With different promoter volumes, the efficiency of ablation rises, plateaus, then falls with increasing volume. (3) At drilling rates of 30 pulses/sec, ablation efficiency approaches rates of 0.1 mm3/sec. LM and SEM observations show a glassy 'pebbled' crater surface indicative of hydroxyapatite that has cooled, condensed, and solidified on the crater walls. Together these results favor the view that a micro-drop promoter-assisted Nd:YAG drill can five clinically useful ablations hard dental tissue.

  9. Rapid synthesis of tin oxide nanostructures by microwave-assisted thermal oxidation for sensor applications

    Science.gov (United States)

    Phadungdhitidhada, S.; Ruankham, P.; Gardchareon, A.; Wongratanaphisan, D.; Choopun, S.

    2017-09-01

    In the present work nanostructures of tin oxides were synthesized by a microwave-assisted thermal oxidation. Tin precursor powder was loaded into a cylindrical quartz tube and further radiated in a microwave oven. The as-synthesized products were characterized by scanning electron microscope, transmission electron microscope, and x-ray diffractometer. The results showed that two different morphologies of SnO2 microwires (MWs) and nanoparticles (NPs) were obtained in one minute of microwave radiation under atmospheric ambient. A few tens of the SnO2 MWs with the length of 10-50 µm were found. Some parts of the MWs were decorated with the SnO2 NPs. However, most of the products were SnO2 NPs with the diameter ranging from 30-200 nm. Preparation under loosely closed system lead to mixed phase SnO-SnO2 NPs with diameter of 30-200 nm. The single-phase of SnO2 could be obtained by mixing the Sn precursor powders with CuO2. The products were mostly found to be SnO2 nanowires (NWs) and MWs. The diameter of SnO2 NWs was less than 50 nm. The SnO2 NPs, MWs, and NWs were in the cassiterite rutile structure phase. The SnO NPs was in the tetragonal structure phase. The growth direction of the SnO2 NWs was observed in (1 1 0) and (2 2 1) direction. The ethanol sensor performance of these tin oxide nanostructures showed that the SnO-SnO2 NPs exhibited extremely high sensitivity. Invited talk at 5th Thailand International Nanotechnology Conference (Nano Thailand-2016), 27-29 November 2016, Nakhon Ratchasima, Thailand.

  10. A Plasma-Assisted Route to the Rapid Preparation of Transition-Metal Phosphides for Energy Conversion and Storage

    KAUST Repository

    Liang, Hanfeng

    2017-06-06

    Transition-metal phosphides (TMPs) are important materials that have been widely used in catalysis, supercapacitors, batteries, sensors, light-emitting diodes, and magnets. The physical and chemical structure of a metal phosphide varies with the method of preparation as the electronic, catalytic, and magnetic properties of the metal phosphides strongly depend on their synthesis routes. Commonly practiced processes such as solid-state synthesis and ball milling have proven to be reliable routes to prepare TMPs but they generally require high temperature and long reaction time. Here, a recently developed plasma-assisted conversion route for the preparation of TMPs is reviewed, along with their applications in energy conversion and storage, including water oxidation electrocatalysis, sodium-ion batteries, and supercapacitors. The plasma-assisted synthetic route should open up a new avenue to prepare TMPs with tailored structure and morphology for various applications. In fact, the process may be further extended to the synthesis of a wide range of transition-metal compounds such as borides and fluorides at low temperature and in a rapid manner.

  11. Application of 3D printing rapid prototyping-assisted percutaneous fixation in the treatment of intertrochanteric fracture.

    Science.gov (United States)

    Zheng, Sheng-Nai; Yao, Qing-Qiang; Mao, Feng-Yong; Zheng, Peng-Fei; Tian, Shu-Chang; Li, Jia-Yi; Yu, Yi-Fan; Liu, Shuai; Zhou, Jin; Hu, Jun; Xu, Yan; Tang, Kai; Lou, Yue; Wang, Li-Ming

    2017-10-01

    The aim of the present study was to investigate the application of 3D printing (3DP) rapid prototyping (RP) technique-assisted percutaneous fixation in the treatment of femoral intertrochanteric fracture (ITF) using proximal femoral nail anti-rotation (PFNA). A total of 39 patients with unstable ITF were included in the current study. Patients were divided into two groups: 19 patients were examined using computed tomography scanning and underwent PFNA with SDP-RP whereas the other 20 patients underwent conventional PFNA treatment. Anatomical data were converted from the Digital Imaging and Communications in Medicine format to the stereolithography format using M3D software. The 3DP-RP model was established using the fused deposition modeling technique and the length and diameter of the main screw blade was measured during the simulation. The postoperative femoral neck-shaft angle (NSA), surgery duration, intraoperative and postoperative blood loss, and the duration of hospital stay were recorded and compared with the corresponding values in conventional surgery. No significant differences were observed in mean PFNA size between the implants used and the preoperative planning estimates. It was demonstrated that the 3DP-RP assisted procedure resulted in more effective reduction of the NSA. Furthermore, patients undergoing 3DP-RP experienced a significant reduction in duration of surgery (P<0.01), as well as reductions in intraoperative (P=0.02) and postoperative (P=0.03) blood loss, compared with conventional surgery. At 6 months post-surgery, no cases of hip varus/vague deformities or implant failure were observed in patients that underwent either the 3DP-RP-assisted or conventional procedure. The results of the present study suggest that the 3DP-RP technique is able to create an accurate model of the ITF, which facilitates surgical planning and fracture reduction, thus improving the efficiency of PFNA surgery for ITFs.

  12. Adiantum philippense L. Frond Assisted Rapid Green Synthesis of Gold and Silver Nanoparticles

    Directory of Open Access Journals (Sweden)

    Duhita G. Sant

    2013-01-01

    Full Text Available Development of an ecofriendly, reliable, and rapid process for synthesis of nanoparticles using biological system is an important bulge in nanotechnology. Antioxidant potential and medicinal value of Adiantum philippense L. fascinated us to utilize it for biosynthesis of gold and silver nanoparticles (AuNPs and AgNPs. The current paper reports utility of aqueous extract of A. philippense L. fronds for the green synthesis of AuNPs and AgNPs. Effect of various parameters on synthesis of nanoparticles was monitored by UV-Vis spectrometry. Optimum conditions for AuNPs synthesis were 1 : 1 proportion of original extract at pH 11 and 5 mM tetrachloroauric acid, whereas optimum conditions for AgNPs synthesis were 1 : 1 proportion of original extract at pH 12 and 9 mM silver nitrate. Characterization of nanoparticles was done by TEM, SAED, XRD, EDS, FTIR, and DLS analyses. The results revealed that AuNPs and AgNPs were anisotropic. Monocrystalline AuNPs and polycrystalline AgNPs measured 10 to 18 nm in size. EDS and XRD analyses confirmed the presence of elemental gold and silver. FTIR analysis revealed a possible binding of extract to AuNPs through –NH2 group and to AgNPs through C=C group. These nanoparticles stabilized by a biological capping agent could further be utilized for biomedical applications.

  13. Murraya Koenigii leaf-assisted rapid green synthesis of silver and gold nanoparticles

    Science.gov (United States)

    Philip, Daizy; Unni, C.; Aromal, S. Aswathy; Vidhu, V. K.

    2011-02-01

    A facile bottom-up 'green' and rapid synthetic route using Murraya Koenigii leaf extract as reducing and stabilizing agent produced silver nanoparticles at ambient conditions and gold nanoparticles at 373 K. The nanoparticles were characterized using UV-vis, transmission electron microscopy (TEM), X-ray diffraction (XRD) and FTIR analysis. This method allows the synthesis of well-dispersed silver and gold nanoparticles having size ˜10 nm and ˜20 nm, respectively. Silver nanoparticles with size ˜10 nm having symmetric SPR band centered at 411 nm is obtained within 5 min of addition of the extract to the solution of AgNO 3 at room temperature. Nearly spherical gold nanoparticles having size ˜20 nm with SPR at 532 nm is obtained on adding the leaf extract to the boiling solution of HAuCl 4. Crystallinity of the nanoparticles is confirmed from the high-resolution TEM images, selected area electron diffraction (SAED) and XRD patterns. From the FTIR spectra it is found that the biomolecules responsible for capping are different in gold and silver nanoparticles. A comparison of the present work with the author's earlier reports on biosynthesis is also included.

  14. Rapid Single-step Formation of Liposomes by Flow Assisted Stationary Phase Interdiffusion.

    Science.gov (United States)

    Has, Chandra; Phapal, Sopan M; Sunthar, P

    2018-01-17

    Laboratory preparation of unilamellar liposomes often involves multiple steps carried out over several hours to achieve a monodisperse size distribution. Here we present a methodology, based on a recently introduced lipid self-assembly principle-stationary phase interdiffusion (SPI)-to prepare large unilamellar vesicles (LUVs) of a monodisperse population in a short period of about 10min. The stationary interface between a lipid-ethanol phase and an aqueous phase is created by a density difference induced convective flow in a horizontal capillary. The average size of the liposomes, as expected from the SPI principle, is modulated only by the temperature and the type of lipids. Lipid concentration, ethanol content, pH of the aqueous phase, and the time duration of the experiment have little influence on the mean diameter of the vesicles. This simple methodology can be easily carried out with a capillary and a micro-needled syringe, and provides a rapid production tool for researchers requiring reproducible liposome suspensions. Refined natural lipids, based on soy and egg lecithin mixtures, yield LUVs in the range 100-200 nm, suitable for drug delivery applications. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Rapid Palatal Expansion in the absence of posterior cross-bite to intercept maxillary incisor crowding in the mixed dentition: a CBCT evaluation of spontaneous changes of untouched permanent molars.

    Science.gov (United States)

    Rosa, M; Lucchi, P; Manti, G; Caprioglio, A

    2016-12-01

    The aim of this study was to investigate the reaction of untouched permanent molars following RPE, anchored on deciduous teeth in the early mixed dentition, aimed to solve maxillary anterior crowding in the absence of posterior cross-bite. A prospective clinical trial comprised 35 consecutive patients (20 males and 15 females) treated by the same orthodontist (MR). All patients showed crowding of the upper permanent incisors in the early mixed dentition in the absence of posterior cross-bite. RPE was anchored on second deciduous molars and on the deciduous canines. CBCT was taken before and after the removal of the RPE appliance. The transverse linear changes in width and the variation in the torque of the permanent molars were measured in the coronal plane. Relief of incisor crowding was found in all patients. The transverse width between permanent molars increased significantly. The apices of the upper permanent molars spontaneously expanded more than the crowns, while the opposite happened on the lower permanent molars. Moreover, the untouched upper permanent molars spontaneously uprighted palatally, while the lower permanent molars spontaneously uprighted buccally. The variation in the torque of the permanent molars mirrored transverse normal growth. In the early mixed dentition and in the absence of posterior cross-bite, it is possible to expand transversally the palate while uprighting the upper permanent molars in the opposite direction. RPE anchored on the deciduous teeth in the early mixed dentition, in the absence of posterior cross-bite, provides an "anticipation of transverse growth" and could be indicated to expand the anterior portion of the maxillary arch perimeter to solve upper incisor crowding.

  16. Estudo das alterações craniofaciais e da importância da expansão rápida da maxila após adenotonsilectomia Study of craniofacial alterations and of the importance of the rapid maxillary expansion after tonsillectomy

    Directory of Open Access Journals (Sweden)

    Silvia Regina Amorim Pereira

    2012-04-01

    Full Text Available A hipertrofia obstrutiva das tonsilas palatinas e faríngeas está associada à respiração oral e pode levar a desequilíbrios faciais. A adenotonsilectomia parece ser insuficiente para o tratamento quando ocorreram alterações anatômicas. Técnicas ortopédicas faciais auxiliam no restabelecimento morfofuncional. Estudo clínico longitudinal prospectivo objetivou observar alterações craniofaciais após adenotonsilectomia e verificar a importância de associar ortopedia ao tratamento. MATERIAL E MÉTODO: Cinquenta e três crianças de ambos os gêneros, entre 6 e 12 anos, divididas em: Grupo 1, 20 crianças com respiração nasal; Grupo 2, 33 crianças com hipertrofia obstrutiva das tonsilas faríngeas e/ou palatinas, submetidas à adenotonsilectomia. Após a cirurgia, este grupo foi subdividido: Grupo 2A, 16 pacientes não tratados com expansão rápida da maxila; Grupo 2B, 17 pacientes tratados com disjunção maxilar. Foram realizadas medidas cefalométricas em norma frontal e lateral anteriores à cirurgia e após 14 meses. Foram utilizados os testes Kruskal-Wallis e Wilcoxon, com nível de significância de 5%. RESULTADOS: A adenotonsilectomia equilibrou o crescimento transversal, sagital e vertical em ambos os grupos, sendo mais efetiva no grupo submetido ao tratamento combinado. CONCLUSÕES: A adenotonsilectomia favoreceu o crescimento facial das crianças com hipertrofia obstrutiva, sendo mais evidente quando associada à expansão maxilar.Obstructive hypertrophy of the tonsils and/or adenoids is associated with mouth breathing and can lead to facial imbalances. Adenotonsillectomy is not enough to treat the anatomic changes. Facial orthopedic techniques aid in morphological and functional recovery. This prospective longitudinal clinical study aimed to observe craniofacial changes after adenotonsillectomy and to verify the importance of linking rapid maxillary expansion to treatment. METHOD: Fifty-three children of both genders

  17. Rapid microwave-assisted synthesis of molecularly imprinted polymers on carbon quantum dots for fluorescent sensing of tetracycline in milk.

    Science.gov (United States)

    Hou, Juan; Li, Huiyu; Wang, Long; Zhang, Ping; Zhou, Tianyu; Ding, Hong; Ding, Lan

    2016-01-01

    In this paper, a novel, selective and eco-friendly sensor for the detection of tetracycline was developed by grafting imprinted polymers onto the surface of carbon quantum dots. A simple microwave-assisted approach was utilized to fabricate the fluorescent imprinted composites rapidly for the first time, which could shorten the polymerization time and simplify the experimental procedure dramatically. The novel composites not only demonstrated excellent fluorescence stability and special binding sites, but also could selectively accumulate target analytes. Under optimal conditions, the relative fluorescence intensity of the composites decreased linearly with increasing the concentration of tetracycline from 20 nM to 14 µM. The detection limit of tetracycline was 5.48 nM. The precision and reproducibility of the proposed sensor were also acceptable. Significantly, the practicality of this ultrasensitive sensor for tetracycline detection in milk was further validated, revealing the advantages of simplicity, sensitivity, selectivity and low cost. This approach combines the high selective adsorption property of molecular imprinted polymers and the sensitivity of fluorescence detection. It is envisioned that the development of fluorescent molecularly imprinted composites will offer a new way of thinking for rapid analysis in complex samples. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Bilateral supernumerary primary maxillary canines

    Directory of Open Access Journals (Sweden)

    Santanu Mukhopadhyay

    2018-01-01

    Full Text Available Supernumerary teeth are more common in the permanent than in primary dentition. In the primary dentition, the anomaly is most frequently observed in the maxillary lateral incisor region, followed by the maxillary midline where they are termed as mesiodens. Supernumerary teeth in the primary canine region are rare. This paper describes a rare case of nonsyndromic supernumerary primary maxillary canine distributed bilaterally in a 4-year-old boy. Both the supernumeraries resembled size and shape of normal primary canine. The right supplemental canine is high labially placed, whereas the left one is seen normally aligned in the dental arch distal to lateral incisor. One of the most significant sequelae of primary supernumerary teeth is their duplication in the permanent series. Radiographic examination of supernumerary primary canine did not indicate any such anomaly in the permanent dentition. The patient was kept under observation.

  19. Maxillary Osteomyelitis: A Rare Entity

    Directory of Open Access Journals (Sweden)

    Ayaaz Habib

    2016-01-01

    Full Text Available Osteomyelitis of the maxilla is now a rare event with the advent of antibiotics. The two predominant causes are odontogenic infections and sinusitis. Immunocompromised states such as diabetes, HIV, and malnutrition increase the risk of osteomyelitis. It is important to recognize this early as it is a difficult entity to treat with potentially serious consequences. We report an unusual case of right sided maxillary osteomyelitis in a lady with poorly controlled diabetes in rural Lincolnshire. Biopsy of the right maxillary bone showed features of acute osteomyelitis. This responded well to a prolonged course of oral antibiotics.

  20. Proximity of maxillary posterior teeth roots to maxillary sinus and adjacent structures using Denta scan?

    OpenAIRE

    Fry, Ramesh Ram; Patidar, Dinesh Chand; Goyal, Samta; Malhotra, Aayush

    2016-01-01

    Aim: The study aimed to investigate the proximity of maxillary posterior teeth roots to maxillary sinus and measure the distance of maxillary posterior teeth roots and the sinus floor as well as the thickness of bone between the roots and alveolar cortical bone using Denta scan?. Materials and Methods: The study samples include Denta scan? images of fifty patients with normally erupted bilateral maxillary first premolar to maxillary second molar. The vertical relationship of each tooth root w...

  1. Structural stability of hydrogenated amorphous carbon overcoats used in heat-assisted magnetic recording investigated by rapid thermal annealing

    KAUST Repository

    Wang, N.

    2013-01-01

    Ultrathin amorphous carbon (a-C) films are extensively used as protective overcoats of magnetic recording media. Increasing demands for even higher storage densities have necessitated the development of new storage technologies, such as heat-assisted magnetic recording (HAMR), which uses laser-assisted heating to record data on high-stability media that can store single bits in extremely small areas (∼1 Tbit/in.2). Because HAMR relies on locally changing the coercivity of the magnetic medium by raising the temperature above the Curie temperature for data to be stored by the magnetic write field, it raises a concern about the structural stability of the ultrathin a-C film. In this study, rapid thermal annealing (RTA) experiments were performed to examine the thermal stability of ultrathin hydrogenated amorphous carbon (a-C:H) films deposited by plasma-enhanced chemical vapor deposition. Structural changes in the a-C:H films caused by RTA were investigated by x-ray photoelectron spectroscopy, Raman spectroscopy, x-ray reflectivity, and conductive atomic force microscopy. The results show that the films exhibit thermal stability up to a maximum temperature in the range of 400-450 °C. Heating above this critical temperature leads to hydrogen depletion and sp 2 clustering. The critical temperature determined by the results of this study represents an upper bound of the temperature rise due to laser heating in HAMR hard-disk drives and the Curie temperature of magnetic materials used in HAMR hard disks. © 2013 American Institute of Physics.

  2. Rapid microwave-assisted synthesis of PVP-coated ultrasmall gadolinium oxide nanoparticles for magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Vahdatkhah, Parisa [Department of Materials Science and Engineering, Sharif University of Technology (Iran, Islamic Republic of); Madaah Hosseini, Hamid Reza, E-mail: Madaah@sharif.ir [Department of Materials Science and Engineering, Sharif University of Technology (Iran, Islamic Republic of); Khodaei, Azin [Department of Materials Science and Engineering, Sharif University of Technology (Iran, Islamic Republic of); Montazerabadi, Ali Reza [Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences (Iran, Islamic Republic of); Irajirad, Rasoul [Biomolecular Image Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences (Iran, Islamic Republic of); Oghabian, Mohamad Ali [Biomolecular Image Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences (Iran, Islamic Republic of); Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences (Iran, Islamic Republic of); Delavari, Hamid H., E-mail: Hamid.delavari@modares.ac.ir [Department of Materials Engineering, Tarbiat Modares University, Tehran, PO Box 14115-143 (Iran, Islamic Republic of)

    2015-05-12

    Highlights: • A rapid microwave-assisted polyol process used to synthesize Gd{sub 2}O{sub 3} nanoparticles. • In situ surface modification of ultrasmall Gd{sub 2}O{sub 3}NPs with PVP has been performed. • Gd{sub 2}O{sub 3}NPs shows considerable increasing of relaxivity in comparison to Gd-chelates. • PVP-covered Gd{sub 2}O{sub 3}NPs show appropriate stability for approximately 15 days. • Spectrophotometric indicates the leaching of free Gd ions not occurred versus time. - Abstract: Synthesis of polyvinyl pyrrolidone (PVP) coated ultrasmall Gd{sub 2}O{sub 3} nanoparticles (NPs) with enhanced T{sub 1}-weighted signal intensity and r{sub 2}/r{sub 1} ratio close to unity is performed by a microwave-assisted polyol process. PVP coated Gd{sub 2}O{sub 3}NPs with spherical shape and uniform size of 2.5 ± 0.5 nm have been synthesized below 5 min and structure and morphology confirmed by HRTEM, XRD and FTIR. The longitudinal (r{sub 1}) and transversal relaxation (r{sub 2}) of Gd{sub 2}O{sub 3}NPs is measured by a 3 T MRI scanner. The results showed considerable increasing of relaxivity for Gd{sub 2}O{sub 3}NPs in comparison to gadolinium chelates which are commonly used for clinical magnetic resonance imaging. In addition, a mechanism for Gd{sub 2}O{sub 3}NPs formation and in situ surface modification of PVP-grafted Gd{sub 2}O{sub 3}NPs is proposed.

  3. Rapid metal extractability tests from polluted mining soils by ultrasound probe sonication and microwave-assisted extraction systems.

    Science.gov (United States)

    García-Salgado, Sara; Quijano, M Ángeles

    2016-12-01

    Ultrasonic probe sonication (UPS) and microwave-assisted extraction (MAE) were used for rapid single extraction of Cd, Cr, Cu, Ni, Pb, and Zn from soils polluted by former mining activities (Mónica Mine, Bustarviejo, NW Madrid, Spain), using 0.01 mol L-1 calcium chloride (CaCl2), 0.43 mol L-1 acetic acid (CH3COOH), and 0.05 mol L-1 ethylenediaminetetraacetic acid (EDTA) at pH 7 as extracting agents. The optimum extraction conditions by UPS consisted of an extraction time of 2 min for both CaCl2 and EDTA extractions and 15 min for CH3COOH extraction, at 30% ultrasound (US) amplitude, whereas in the case of MAE, they consisted of 5 min at 50 °C for both CaCl2 and EDTA extractions and 15 min at 120 °C for CH3COOH extraction. Extractable concentrations were determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). The proposed methods were compared with a reduced version of the corresponding single extraction procedures proposed by the Standards, Measurements and Testing Programme (SM&T). The results obtained showed a great variability on extraction percentages, depending on the metal, the total concentration level and the soil sample, reaching high values in some areas. However, the correlation analysis showed that total concentration is the most relevant factor for element extractability in these soil samples. From the results obtained, the application of the accelerated extraction procedures, such as MAE and UPS, could be considered a useful approach to evaluate rapidly the extractability of the metals studied.

  4. Efeitos transversais da expansão rápida da maxila em pacientes com má oclusão de Classe II: avaliação por Tomografia Computadorizada Cone-Beam Transverse effects of rapid maxillary expansion in Class II malocclusion patients: a Cone-Beam Computed Tomography study

    Directory of Open Access Journals (Sweden)

    Carolina Baratieri

    2010-10-01

    Full Text Available OBJETIVO: avaliar por meio de Tomografia Computadorizada Cone-Beam (TCCB os efeitos transversais, imediatos e após o período de contenção, da expansão rápida da maxila (ERM em pacientes com má oclusão de Classe II. MÉTODOS: dezessete crianças (idade inicial média de 10,36 anos com má oclusão de Classe II e deficiência transversal esquelética da maxila foram submetidas ao protocolo de ERM com aparelho expansor de Haas. TCCBs foram realizadas antes dos procedimentos clínicos (T1, imediatamente após a estabilização do parafuso expansor (T2 e após completados 6 meses de contenção e removido o aparelho (T3. Com o software Dolphin, foram possíveis a manipulação das imagens e as mensurações. O teste t de Student pareado foi utilizado para identificar significância estatística (pOBJECTIVE: The aim of this study was to evaluate by Cone-Beam Computed Tomography (CBCT transversal responses, immediately and after the retention period, to rapid maxillary expansion (RME, in Class II malocclusion patients. METHODS: Seventeen children (mean initial age of 10.36 years, with Class II malocclusion and skeletal constricted maxilla, underwent Haas´ protocol for RME. CBCT scans were taken before treatment (T1, at the end of the active expansion phase (T2 and after the retention period of six months (T3. The scans were managed in Dolphin software, where landmarks were marked and measured, on a coronal slice passing through the upper first molar. The paired Student´s t-test was used to identify significant differences (p<0.05 between T2 and T1, T3 and T2, and T3 and T1. RESULTS: Immediately after RME, the mean increase in maxillary basal, alveolar and dental width was 1.95 mm, 4.30 mm and 6.89 mm, respectively. This was accompanied by buccal inclination of the right (7.31° and left (6.46° first molars. At the end of the retention period, the entire transverse dimension increased was maintained and the dentoalveolar inclination resumed

  5. Avaliação transversal e vertical da maxila, após expansão rápida, utilizando um método de padronização das radiografias póstero-anteriores Transversal and vertical maxillary evaluation, after rapid expansion, using a standardization method for posteroanterior radiographs

    Directory of Open Access Journals (Sweden)

    Gustavo Mattos Barreto

    2005-12-01

    Full Text Available OBJETIVO: na presente pesquisa utilizou-se o aparelho Hyrax tendo como objetivo avaliar as alterações transversais e verticais da maxila. Foram selecionados 20 pacientes de ambos os gêneros, entre 7 e 11 anos de idade, que apresentavam mordida cruzada posterior uni ou bilateral. METODOLOGIA: foram realizadas telerradiografias em norma frontal (PA antes e após a expansão. A fim de evitar que a falta de padronização dessas radiografias pudesse influenciar nos resultados, idealizou-se um método de padronização para tais radiografias. RESULTADOS E CONCLUSÕES: os resultados mostraram que a correção da mordida cruzada posterior com o aparelho Hyrax, que ocorreu em todos os casos, foi em função tanto da abertura da sutura palatina mediana como também da inclinação dos molares. A medida JgE-JgD relacionada com a expansão maxilar aumentou significantemente em todos os casos tratados. Nas avaliações dentárias, as medidas verticais não apresentaram diferenças significantes, ao contrário das medidas transversais (FTE-FTD; FBE-FBD; LO.BTE; LO.BTD; BTE.BTD. A largura da cavidade nasal também aumentou significantemente (CNE-CND. O método de padronização proposto permite, portanto, utilizar as medidas que avaliam a expansão rápida da maxila, através das radiografias póstero-anteriores, com segurança, também no sentido vertical.AIM: in the atresia maxillary cases, the most indicated treatment is rapid maxillary expansion that can be achieved by different therapies. In the present research the Hyrax appliance was used in order to evaluate the transverse and vertical outcomes in maxillary base. METHODS: twenty patients of both gender, from 7 to 11 years old, presenting uni or bilateral posterior crossbite were selected. Posteroanterior radiographs were performed before and after expansion. These radiographs were standardized in order to avoid that problems with lack of standardization influence the results. RESULTS AND CONCLUSION

  6. A SIMPLE AND RAPID MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHT MASS SPECTROMETRY METHOD TO SCREEN FISH PLASMA SAMPLES FOR ESTROGEN-RESPONSIVE BIOMARKERS

    Science.gov (United States)

    In this study, we describe and evaluate the performance of a simple and rapid mass spectral method for screening fish plasma for estrogen-responsive biomarkers using matrix assisted laster desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) couopled with a short...

  7. Mucocoele of the maxillary sinus

    Directory of Open Access Journals (Sweden)

    Perić Aleksandar

    2007-01-01

    Full Text Available Background. Mucocoele is histopathologically benign, cystic change of paranasal sinuses filled with mucoid contents, which with its growth is pressuring and destroying local bone walls. In only 3% of the cases it can be localized in maxillary sinuses. Etiology is unknown. Pyocoele develops by secondary infection. Case report. The male patient was 21 years old. His symptoms were runny nose with thick contents and heavy breathing on the right side of the nose, headaches, as well as the swelling of the right cheek. During clinical examination, the expansive change was found. It was completely closing the right side of the nose cavity. Computerized tomography (CT of paranasal cavities showed excessive expansion of the right maxillary sinus, with very thinned walls, while the cavity was filled with liquid. After antibiotics therapy, the radical operation of the right maxillary sinus was performed, based on Caldwell Luc method. The frontal wall was found to be extremely convex and thinned, while the medial wall was with dehiscention. The cystic change was extirpated. Mucocoele was proved by pathohistologic findings. Its wall was about 2 mm thick and it showed squamous metaplasia in the large part of the mucocoela epithel. In the submucosa fibrosis and inflammatory infiltrate was present. Postoperative follow-up was under control. Clinically and radiographycaly, six months after therapy, the patient does not have troubles. Conclusion. The rare localization of the mucocoeles in maxillary sinus can be explained with the width of the maxillary ostia. Infected mucocoeles, expanded to the local anatomical structures, should be operated on with classic radical surgical operation. .

  8. Microwave assisted extraction-solid phase extraction for high-efficient and rapid analysis of monosaccharides in plants.

    Science.gov (United States)

    Zhang, Ying; Li, Hai-Fang; Ma, Yuan; Jin, Yan; Kong, Guanghui; Lin, Jin-Ming

    2014-11-01

    Monosaccharides are the fundamental composition units of saccharides which are a common source of energy for metabolism. An effective and simple method consisting of microwave assisted extraction (MAE), solid phase extraction (SPE) and high performance liquid chromatography-refractive index detector (HPLC-RID) was developed for rapid detection of monosaccharides in plants. The MAE was applied to break down the structure of the plant cells and release the monosaccharides, while the SPE procedure was adopted to purify the extract before analysis. Finally, the HPLC-RID was employed to separate and analyze the monosaccharides with amino column. As a result, the extraction time was reduced to 17 min, which was nearly 85 times faster than soxhlet extraction. The recoveries of arabinose, xylose, fructose and glucose were 85.01%, 87.79%, 103.17%, and 101.24%, with excellent relative standard deviations (RSDs) of 1.94%, 1.13%, 0.60% and 1.67%, respectively. The proposed method was demonstrated to be efficient and time-saving, and had been applied to analyze monosaccharides in tobacco and tea successfully. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Innovative procedure for computer-assisted genioplasty: three-dimensional cephalometry, rapid-prototyping model and surgical splint.

    Science.gov (United States)

    Olszewski, R; Tranduy, K; Reychler, H

    2010-07-01

    The authors present a new procedure of computer-assisted genioplasty. They determined the anterior, posterior and inferior limits of the chin in relation to the skull and face with the newly developed and validated three-dimensional cephalometric planar analysis (ACRO 3D). Virtual planning of the osteotomy lines was carried out with Mimics (Materialize) software. The authors built a three-dimensional rapid-prototyping multi-position model of the chin area from a medical low-dose CT scan. The transfer of virtual information to the operating room consisted of two elements. First, the titanium plates on the 3D RP model were pre-bent. Second, a surgical guide for the transfer of the osteotomy lines and the positions of the screws to the operating room was manufactured. The authors present the first case of the use of this model on a patient. The postoperative results are promising, and the technique is fast and easy-to-use. More patients are needed for a definitive clinical validation of this procedure. Copyright 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  10. Rapid assignment of malting barley varieties by matrix-assisted laser desorption-ionisation - Time-of-flight mass spectrometry.

    Science.gov (United States)

    Šedo, Ondrej; Kořán, Michal; Jakešová, Michaela; Mikulíková, Renata; Boháč, Michal; Zdráhal, Zbyněk

    2016-09-01

    A method for discriminating malting barley varieties based on direct matrix-assisted laser desorption-ionisation - time-of-flight mass spectrometry (MALDI-TOF MS) fingerprinting of proteins was developed. Signals corresponding to hordeins were obtained by simple mixing of powdered barley grain with a MALDI matrix solution containing 12.5mgmL(-1) of ferulic acid in an acetonitrile:water:formic acid 50:33:17 v/v/v mixture. Compared to previous attempts at MALDI-TOF mass spectrometric analysis of barley proteins, the extraction and fractionation steps were practically omitted, resulting in a significant reduction in analytical time and costs. The discriminatory power was examined on twenty malting barley varieties and the practicability of the method was tested on sixty barley samples acquired from Pilsner Urquell Brewery. The method is proposed as a rapid tool for variety assignment and purity determination of malting barley that may replace gel electrophoresis currently used for this purpose. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Generation of Aptamers from A Primer-Free Randomized ssDNA Library Using Magnetic-Assisted Rapid Aptamer Selection

    Science.gov (United States)

    Tsao, Shih-Ming; Lai, Ji-Ching; Horng, Horng-Er; Liu, Tu-Chen; Hong, Chin-Yih

    2017-04-01

    Aptamers are oligonucleotides that can bind to specific target molecules. Most aptamers are generated using random libraries in the standard systematic evolution of ligands by exponential enrichment (SELEX). Each random library contains oligonucleotides with a randomized central region and two fixed primer regions at both ends. The fixed primer regions are necessary for amplifying target-bound sequences by PCR. However, these extra-sequences may cause non-specific bindings, which potentially interfere with good binding for random sequences. The Magnetic-Assisted Rapid Aptamer Selection (MARAS) is a newly developed protocol for generating single-strand DNA aptamers. No repeat selection cycle is required in the protocol. This study proposes and demonstrates a method to isolate aptamers for C-reactive proteins (CRP) from a randomized ssDNA library containing no fixed sequences at 5‧ and 3‧ termini using the MARAS platform. Furthermore, the isolated primer-free aptamer was sequenced and binding affinity for CRP was analyzed. The specificity of the obtained aptamer was validated using blind serum samples. The result was consistent with monoclonal antibody-based nephelometry analysis, which indicated that a primer-free aptamer has high specificity toward targets. MARAS is a feasible platform for efficiently generating primer-free aptamers for clinical diagnoses.

  12. Rapid microwave-assisted synthesis of highly luminescent nitrogen-doped carbon dots for white light-emitting diodes

    Science.gov (United States)

    Wang, Yaling; Zheng, Jingxia; Wang, Junli; Yang, Yongzhen; Liu, Xuguang

    2017-11-01

    Highly luminescent nitrogen-doped carbon dots (N-CDs) were synthesized rapidly by one-step microwave-assisted hydrothermal method using citric acid as carbon source and ethylenediamine as dopant. The influences of reaction temperature, reaction time and raw material ratio on the fluorescence performance of N-CDs were investigated. Then N-CDs with the highest quantum yield were selected as fluorescent materials for fabricating white light-emitting diodes (LEDs). Highly luminescent N-CDs with the quantum yield of 75.96% and blue-to-red spectral composition of 51.48% were obtained at the conditions of 180 °C, 8 min and the molar ratio of citric acid to ethylenediamine 2:1. As-prepared highly luminescent N-CDs have an average size of 6.06 nm, possess extensive oxygen- and nitrogen-containing functional groups on their surface, and exhibit strong absorption in ultraviolet region. White LEDs based on the highly luminescent N-CDs emit warm white light with color coordinates of (0.42, 0.40) and correlated color temperature of 3416 K.

  13. Facile and rapid one-pot microwave-assisted synthesis of Pd-Ni magnetic nanoalloys confined in mesoporous carbons

    Energy Technology Data Exchange (ETDEWEB)

    Martínez de Yuso, Alicia; Le Meins, Jean-Marc [Université de Strasbourg, Université de Haute-Alsace, Institut de Science des Matériaux de Mulhouse, CNRS UMR (France); Oumellal, Yassine; Paul-Boncour, Valérie; Zlotea, Claudia [Institut de Chimie et des Matériaux Paris Est, UMR 7182, CNRS-UPEC (France); Matei Ghimbeu, Camelia, E-mail: camelia.ghimbeu@uha.fr [Université de Strasbourg, Université de Haute-Alsace, Institut de Science des Matériaux de Mulhouse, CNRS UMR (France)

    2016-12-15

    An easy and rapid one-pot microwave-assisted soft-template synthesis method for the preparation of Pd-Ni nanoalloys confined in mesoporous carbon is reported. This approach allows the formation of mesoporous carbon and the growth of the particles at the same time, under short microwave irradiation (4 h) compared to the several days spent for the classical approach. In addition, the synthesis steps are diminished and no thermopolymerization step or reduction treatment being required. The influence of the Pd-Ni composition on the particle size and on the carbon characteristics was investigated. Pd-Ni solid solutions in the whole composition range could be obtained, and the metallic composition proved to have an important effect on the nanoparticle size but low influence on carbon textural properties. Small and uniformly distributed nanoparticles were confined in mesoporous carbon with uniform pore size distribution, and dependence between the nanoparticle size and the nanoalloy composition was observed, i.e., increase of the particle size with increasing the Ni content (from 5 to 14 nm). The magnetic properties of the materials showed a strong nanoparticle size and/or composition effect. The blocking temperature of Pd-Ni nanoalloys increases with the increase of Ni amount and therefore of particle size. The magnetization values are smaller than the bulk counterpart particularly for the Ni-rich compositions due to the formed graphitic shells surrounding the particles inducing a dead magnetic layer.

  14. Internal maxillary artery pseudoaneurysm in a case of mandibular fracture

    Directory of Open Access Journals (Sweden)

    Karanth Siddharth

    2007-01-01

    Full Text Available We report a rare case of internal maxillary artery pseudoaneurysm in a patient with a subcondylar fracture of the mandible. Though traumatic pseudoaneurysm in the craniofacial region is a known entity, a situation in which a closed mandibular fracture presents as a rapidly growing swelling in the neck and facial region is a rare presentation. Such a warning sign should be taken seriously and investigated further.

  15. Effects of a three-dimensional bimetric maxillary distalizing arch.

    Science.gov (United States)

    Uçem, T T; Yüksel, S; Okay, C; Gülşen, A

    2000-06-01

    This study aimed to investigate the dental effects of a three-dimensional (3D) bimetric maxillary distalizing arch. The Wilson rapid molar distalization appliance for Class II molar correction was used in 14 patients (10 girls and four boys with a mean age of 12.18 years). The open coil springs were activated with bent Omega stops and Class II intermaxillary elastics. The mandibular anchorage was gained by a 0.016 x 0.016 utility arch with a 3D lingual arch or a lip bumper with a standard lingual arch. The lateral cephalograms taken before and after treatment formed the material of the research. A Wilcoxon test was used to statistically evaluate the treatment effects. The results showed that the distal tipping of the maxillary first and second molars, and first and second premolars and canines were statistically significant. Significant distal movement occurred in all posterior and canine teeth. The maxillary first molar distalization was found to be 3.5 mm. The maxillary incisor showed significant proclination and protrusion. The decrease in overbite was found to be statistically significant. The mandibular plane angle significantly increased by a mean of 0.5 mm. In addition, significant soft tissue changes were observed.

  16. THE EFFECTS OF MAXILLARY EXPANSION ON THE SOFT TISSUE FACIAL PROFILE

    Directory of Open Access Journals (Sweden)

    Işıl ARAS

    2017-10-01

    Full Text Available Purpose: The aims of this retrospective study were to evaluate the possible changes in soft tissue facial profile induced by orthopedic rapid maxillary expansion (RME and surgically assisted rapid maxillary expansion (SARME, and to correlate them with the underlying hard tissue alterations. Materials and Methods: 16 patients who received bone borne SARME and 25 patients who were subjected to RME using metal cast splint hyrax appliance were analyzed retrospectively. This research was conducted on lateral cephalometric radiographs taken on 2 occasions: before expansion (T1 and at the beginning of any further orthodontic treatment (T2. Investigated lateral cephalometric parameters consisted of Holdaway soft tissue measurements with some supplementary soft tissue, skeletal and dental assessments. Results: The acquisition of T2 cephalograms which conforms to the initiation of further orthodontic treatment corresponded to 83.25±3.51 days for SARME and 85.68±4.37 days for RME after the expansion was completed. The only significant change in soft tissue profile of the SARME group was a decrease in upper lip thickness (p<0.05, whereas in the RME group, decrease in soft tissue facial profile angle and increase in H angle were found to be statistically significant (p<0.05 for each. For the RME group, the changes in soft tissue facial profile angle and H angle correlated only with the changes in SNB angle (p<0.05. Conclusion: While bone-borne SARME did not seem to possess the potential to alter soft tissue profile, tooth-borne RME caused a more convex soft tissue profile related to a reduction in SNB.

  17. Avaliação por tomografia computadorizada helicoidal dos efeitos da expansão rápida da maxila no posicionamento condilar em pacientes com mordida cruzada posterior funcional Evaluation with helicoidal computed tomography of rapid maxillary expansion effects in the condylar position of patients with functional posterior crossbite

    Directory of Open Access Journals (Sweden)

    Edgard Norões Rodrigues da Matta

    2009-10-01

    Full Text Available OBJETIVO: este estudo clínico avaliou, por meio da tomografia computadorizada helicoidal, os efeitos da expansão rápida da maxila no posicionamento condilar de pacientes com mordida cruzada posterior funcional na fase da dentadura mista. MÉTODOS: dez pacientes com faixa etária entre os 7 anos e 2 meses e os 11 anos e 2 meses - apresentando mordida cruzada posterior funcional, com desvio da linha média de pelo menos 2,5mm para o lado do cruzamento - foram tratados com expansão rápida da maxila. Após a obtenção de cortes tomográficos sagitais da articulação temporomandibular, as medidas dos espaços articulares anterior, posterior e superior foram realizadas e o posicionamento relativo do côndilo foi calculado. Utilizando-se cortes tomográficos axiais, avaliou-se o posicionamento anteroposterior e transversal dos côndilos em relação às estruturas da base craniana. RESULTADOS: foram identificadas diferenças significativas, antes do tratamento, entre os espaços articulares posteriores, na posição relativa do côndilo e um posicionamento mais anterior e mais próximo ao plano sagital mediano do côndilo do lado não-cruzado. Após o tratamento, não foram evidenciadas diferenças significativas nessas medidas. CONCLUSÕES: após a expansão rápida da maxila, um posicionamento mais centralizado dos côndilos nas fossas articulares foi observado, além de uma maior simetria anteroposterior e transversal entre os mesmos.AIM: This clinical study evaluated, through helicoidal computed tomography (CT, the effects of rapid maxillary expansion in the condylar position of patients with functional posterior crossbite in mixed dentition stage. METHODS: Ten patients aged between 7 years and 2 months and 11 years and 2 months were selected. This patients which presented functional unilateral posterior crossbite with mandibular midline deviation of at least 2.5mm to the crossbite side were submitted to rapid maxillary expansion. After

  18. Rapid Identification of the Foodborne Pathogen Trichinella spp. by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.

    Science.gov (United States)

    Mayer-Scholl, Anne; Murugaiyan, Jayaseelan; Neumann, Jennifer; Bahn, Peter; Reckinger, Sabine; Nöckler, Karsten

    2016-01-01

    Human trichinellosis occurs through consumption of raw or inadequately processed meat or meat products containing larvae of the parasitic nematodes of the genus Trichinella. Currently, nine species and three genotypes are recognized, of which T. spiralis, T. britovi and T. pseudospiralis have the highest public health relevance. To date, the differentiation of the larvae to the species and genotype level is based primarily on molecular methods, which can be relatively time consuming and labor intensive. Due to its rapidness and ease of use a matrix assisted laser desorption / ionization time of flight mass spectrometry (MALDI-TOF MS) reference spectra database using Trichinella strains of all known species and genotypes was created. A formicacid/acetonitrile protein extraction was carried out after pooling 10 larvae of each Trichinella species and genotype. Each sample was spotted 9 times using α-cyano 4-hydoxy cinnamic acid matrix and a MicroFlex LT mass spectrometer was used to acquire 3 spectra (m/z 2000 to 20000 Da) from each spot resulting in 27 spectra/species or genotype. Following the spectra quality assessment, Biotyper software was used to create a main spectra library (MSP) representing nine species and three genotypes of Trichinella. The evaluation of the spectra generated by MALDI-TOF MS revealed a classification which was comparable to the results obtained by molecular methods. Also, each Trichinella species utilized in this study was distinct and distinguishable with a high confidence level. Further, different conservation methods such as freezing and conservation in alcohol and the host species origin of the isolated larvae did not have a significant influence on the generated spectra. Therefore, the described MALDI-TOF MS can successfully be implemented for both genus and species level identification and represents a major step forward in the use of this technique in foodborne parasitology.

  19. Rapid Identification of the Foodborne Pathogen Trichinella spp. by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.

    Directory of Open Access Journals (Sweden)

    Anne Mayer-Scholl

    Full Text Available Human trichinellosis occurs through consumption of raw or inadequately processed meat or meat products containing larvae of the parasitic nematodes of the genus Trichinella. Currently, nine species and three genotypes are recognized, of which T. spiralis, T. britovi and T. pseudospiralis have the highest public health relevance. To date, the differentiation of the larvae to the species and genotype level is based primarily on molecular methods, which can be relatively time consuming and labor intensive. Due to its rapidness and ease of use a matrix assisted laser desorption / ionization time of flight mass spectrometry (MALDI-TOF MS reference spectra database using Trichinella strains of all known species and genotypes was created. A formicacid/acetonitrile protein extraction was carried out after pooling 10 larvae of each Trichinella species and genotype. Each sample was spotted 9 times using α-cyano 4-hydoxy cinnamic acid matrix and a MicroFlex LT mass spectrometer was used to acquire 3 spectra (m/z 2000 to 20000 Da from each spot resulting in 27 spectra/species or genotype. Following the spectra quality assessment, Biotyper software was used to create a main spectra library (MSP representing nine species and three genotypes of Trichinella. The evaluation of the spectra generated by MALDI-TOF MS revealed a classification which was comparable to the results obtained by molecular methods. Also, each Trichinella species utilized in this study was distinct and distinguishable with a high confidence level. Further, different conservation methods such as freezing and conservation in alcohol and the host species origin of the isolated larvae did not have a significant influence on the generated spectra. Therefore, the described MALDI-TOF MS can successfully be implemented for both genus and species level identification and represents a major step forward in the use of this technique in foodborne parasitology.

  20. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for rapid identification of fungal rhinosinusitis pathogens.

    Science.gov (United States)

    Huang, Yanfei; Wang, Jinglin; Zhang, Mingxin; Zhu, Min; Wang, Mei; Sun, Yufeng; Gu, Haitong; Cao, Jingjing; Li, Xue; Zhang, Shaoya; Lu, Xinxin

    2017-03-01

    Filamentous fungi are among the most important pathogens, causing fungal rhinosinusitis (FRS). Current laboratory diagnosis of FRS pathogens mainly relies on phenotypic identification by culture and microscopic examination, which is time consuming and expertise dependent. Although matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MS has been employed to identify various fungi, its efficacy in the identification of FRS fungi is less clear. A total of 153 FRS isolates obtained from patients were analysed at the Clinical Laboratory at the Beijing Tongren Hospital affiliated to the Capital Medical University, between January 2014 and December 2015. They were identified by traditional phenotypic methods and Bruker MALDI-TOF MS (Bruker, Biotyper version 3.1), respectively. Discrepancies between the two methods were further validated by sequencing. Among the 153 isolates, 151 had correct species identification using MALDI-TOF MS (Bruker, Biot 3.1, score ≥2.0 or 2.3). MALDI-TOF MS enabled identification of some very closely related species that were indistinguishable by conventional phenotypic methods, including 1/10 Aspergillus versicolor, 3/20 Aspergillus flavus, 2/30 Aspergillus fumigatus and 1/20 Aspergillus terreus, which were misidentified by conventional phenotypic methods as Aspergillus nidulans, Aspergillus oryzae, Aspergillus japonicus and Aspergillus nidulans, respectively. In addition, 2/2 Rhizopus oryzae and 1/1 Rhizopus stolonifer that were identified only to the genus level by the phenotypic method were correctly identified by MALDI-TOF MS. MALDI-TOF MS is a rapid and accurate technique, and could replace the conventional phenotypic method for routine identification of FRS fungi in clinical microbiology laboratories.

  1. Expansão rápida da maxila: avaliação de dois métodos de reconstrução 3D por meio de um modelo laboratorial Rapid maxillary expansion: evaluation of two methods of 3D reconstruction by means of a laboratorial model

    Directory of Open Access Journals (Sweden)

    Pollyana Marques de Moura

    2009-02-01

    Full Text Available OBJETIVO: a proposta deste artigo é apresentar um modelo laboratorial para aquisição de imagens tomográficas para avaliação tridimensional do procedimento de expansão rápida da maxila (ERM. MÉTODOS: o procedimento de expansão rápida da maxila foi realizado em crânio seco e os exames foram executados em tomógrafo de alta resolução e em tomógrafo de feixe cônico, antes e depois da ERM. RESULTADOS: as imagens obtidas a partir do crânio seco, tomografia computadorizada multislice (TC e tomografia volumétrica (CBCT produziram resultados semelhantes para avaliação da abertura da sutura palatina mediana. CONCLUSÃO: a utilização de cortes tomográficos, adquiridos tanto por meio de tomógrafo computadorizado de alta resolução quanto por meio da técnica cone beam, possibilitou a reconstrução 3D da maxila com objetivo de oferecer a real avaliação da abertura intermaxilar.OBJECTIVE: This paper proposes to present a laboratorial model for acquisition of tomographic images for three-dimensional evaluation of the rapid maxillary expansion procedure. METHODS: The procedure of rapid maxillary expansion was developed using a dry skull and the images were acquired from a multi-slice tomography and a volumetric tomography. The examinations were taken prior to and after the ERM. RESULTS: The images acquired from the skull, multislice computed tomography (CT and cone beam computed tomography (CBCT had produced similar results. CONCLUSION: The use of tomographic slices, acquired by means of high resolution computerized tomography, as well as the cone beam technique, make possible the three-dimensional reconstruction of the palatomaxillary region in order to offer the real evaluation of the sutural opening.

  2. Sagittal, vertical and transversal dimensions of the maxillary complex in patients with ectopic maxillary canines

    DEFF Research Database (Denmark)

    Larsen, H J; Sørensen, H B; Artmann, L

    2010-01-01

    To analyse the craniofacial maxillary complex in cases with labially and palatally located ectopic canines, subgrouped accordingly: Group I: no deviations in the dentition; Group IIa: deviations in the maxillary incisors only; Group IIb: deviations in the dentition in general....

  3. Ultrasound assisted dispersive liquid-liquid microextraction followed by injector port silylation: a novel method for rapid determination of quinine in urine by GC-MS.

    Science.gov (United States)

    Jain, Rajeev; Mudiam, Mohana Krishna Reddy; Ch, Ratnasekhar; Chauhan, Abhishek; Khan, Haider A; Murthy, Rc

    2013-09-01

    Silylation is a widely used derivatization method for the analysis of polar analytes by GC-MS. Ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) is an ecofriendly, rapid and simple microextraction method. For the first time, a novel approach has been developed and applied for the analysis of quinine in urine by combining UA-DLLME with injection port silylation. The LOD and LOQ were found to be 5.4 and 18 ng/ml. The intra- and inter-day precisions were less than 5 and 8%, respectively. Mean recoveries of quinine were found to be in the range of 87 to 96%. Ultrasound-assisted dispersive liquid-liquid microextraction is rapid, simple and consumes less reagent for the analysis of polar analytes such as quinine.

  4. Cone-Beam computed tomography evaluation of maxillary expansion in twins with cleft lip and palate

    Directory of Open Access Journals (Sweden)

    Luciane Macedo de Menezes

    2012-04-01

    Full Text Available OBJECTIVE: The establishment of normal occlusal relationships in patients with cleft lip and palate using rapid maxillary expansion may promote good conditions for future rehabilitation. OBJECTIVE: This study describes the clinical case of monozygotic twins with unilateral cleft lip and palate at the age of mixed dentition, who were treated using the same rapid maxillary expansion protocol, but with two different screws (conventional and fan-type expansion screw. Results were evaluated using plaster models, intraoral and extraoral photographs, and Cone-Beam computed tomography (CBCT scans obtained before the beginning of the treatment, (T1. METHODS: The patients were followed up for 6 months after maxillary expansion, when the same tests requested at T1 were obtained again for review (T2. T1 and T2 results were compared using lateral cephalometric tracings and measurements of the intercanine and intermolar distances in the plaster models using a digital caliper. RESULTS: The two types of expansion screws corrected the transverse discrepancy in patients with cleft lip and palate. The shape of the upper arches improved at 10 days after activation. CONCLUSION: CBCT scans provide detailed information about craniofacial, maxillary and mandibular changes resulting from rapid maxillary expansion. The most adequate screw for each type of malocclusion should be chosen after detailed examination of the dental arches.

  5. Maxillary sinusitis with pulmonary tuberculosis.

    Science.gov (United States)

    Upadhyay, Rashmi; Prakash, Ved; Singh, Abhishek Bahadur; Saheer, S

    2014-08-01

    Tubercular infection of the nasal cavity is an infrequently encountered condition. More so, after the discovery of relevant antibiotics, nasal sinus tuberculosis is not commonly seen. Few cases have reported tuberculosis of the paranasal sinuses, nasopharynx and larynx. With the increasing incidence of HIV, these rare forms of infection have started re-emerging. We present a case of a middle aged man presenting with nasal cavity lesion along with pulmonary tuberculosis, which came to light only after the diagnosis of maxillary sinus tuberculosis. 2014 BMJ Publishing Group Ltd.

  6. Aneurismatisk knoglecyste i sinus maxillaris

    DEFF Research Database (Denmark)

    Danielsen, Annegrete Aalkjær; Jensen, Margarat Malgorzata; Iyer, Victor Vishwanath

    2017-01-01

    This case report describes a primary aneurysmal bone cyst in the maxillary sinus of a 50-year-old woman. She had nonspecific symptoms through four years of tearing, muscle tension in the face and neck as well as a sense of altered sound of speech. A magnetic resonance imaging of the facial skeleton...... showed multiple cystic processes with liquid mirror in nearly all large cysts. Histology confirmed the diagnosis of a rare aneurysmal bone cyst, and the operation was done by endoscopic resection. At the one-month post-operative control there was no recurrence....

  7. Effect of rapid maxillary expansion on the dimension of the nasal cavity and on facial morphology assessed by acoustic rhinometry and rhinomanometry Efeito da expansão rápida da maxila na dimensão da cavidade nasal e morfologia facial pela rinometria acústica e rinomanometria

    Directory of Open Access Journals (Sweden)

    Carla Enoki Itikawa

    2012-08-01

    Full Text Available OBJECTIVE: To assess the effects of rapid maxillary expansion on facial morphology and on nasal cavity dimensions of mouth breathing children by acoustic rhinometry and computed rhinomanometry. METHODS: Cohort; 29 mouth breathing children with posterior crossbite were evaluated. Orthodontic and otorhinolaryngologic documentation were performed at three different times, i.e., before expansion, immediately after and 90 days following expansion. RESULTS: The expansion was accompanied by an increase of the maxillary and nasal bone transversal width. However, there were no significant differences in relation to mucosal area of the nose. Acoustic rhinometry showed no difference in the minimal cross-sectional area at the level of the valve and inferior turbinate between the periods analyzed, although rhinomanometry showed a statistically significant reduction in nasal resistance right after expansion, but were similar to pre-treatment values 90 days after expansion. CONCLUSION: The maxillary expansion increased the maxilla and nasal bony area, but was inefficient to increase the nasal mucosal area, and may lessen the nasal resistance, although there was no difference in nasal geometry. Significance: Nasal bony expansion is followed by a mucosal compensation.OBJETIVO: avaliar o efeito da expansão rápida da maxila na dimensão da cavidade nasal e na morfologia facial através da rinometria acústica e rinomanometria computadorizada. MÉTODOS: foram avaliadas 29 crianças na fase de dentição mista, portadoras de respiração bucal e mordida cruzada posterior. A documentação ortodôntica e a avaliação otorrinolaringológica foram realizadas em três tempos - antes da expansão rápida da maxila, imediatamente após e 90 dias depois. RESULTADOS: a expansão promoveu um aumento na dimensão da cavidade nasal e na maxila transversalmente. Contudo, não houve diferenças significativas na área da mucosa nasal. A rinometria acústica mostrou que n

  8. Giant complex odontoma of the maxillary antrum

    African Journals Online (AJOL)

    1983-04-30

    Apr 30, 1983 ... Giant complex odontoma of the maxillary antrum. A case report. DIANNE B. MENDELSOHN, Y. HERTZANU, R. B. J. GLASS, G. KASSNER,. M. ALTINI. Summary ... completely filled the maxillary antrum, resulting in elevation of the orbit and .... out cortical bone, resulting in facial asymmetry. Radiographically ...

  9. Microwave-assisted extraction and rapid isolation of ursolic acid from the leaves of Eucalyptus × hybrida Maiden and its quantification using HPLC-diode array technique.

    Science.gov (United States)

    Verma, Subash C; Jain, Chhoten L; Kumari, Amita; Padhi, Madan M; Devalla, Ramesh B

    2013-04-01

    Ursolic acid (UA) is the most important bioactive phytoconstituent of Eucalyptus × hybrida Maiden leaves and exhibits anticancer, antimutagenic, anti-inflammatory, antioxidative, and antiprotozoal activities. In this study, microwave-assisted extraction technique was employed for rapid isolation of UA from the leaves of Eucalyptus × hybrida and simultaneously HPLC-diode array method was developed for the quantification of UA. Effects of several experimental parameters on the extraction efficiencies of UA, such as type and volume of extraction solvents, microwave power and extraction time, were evaluated. The optimal extraction conditions were found to be 20 mL of a mixture of chloroform/methanol, 60:40; liquid-to-material ratio, 4:1; preleaching time, 10 min; microwave power, 600 W; temperature, 50°C; and microwave irradiation time, 5 min. Under the optimum conditions, the yield of UA was found to be 1.95 ± 0.08% in the dry leaves of Eucalyptus × hybrida. The results showed that microwave-assisted extraction is a more rapid extraction method with higher yield and lower solvent consumptions than the conventional method. It is a faster, convenient, and appropriate method and it may be used for rapid isolation and quantification of UA and other important phytoconstituents present in the leaves of Eucalyptus × hybrida. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Comparison of transverse changes during maxillary expansion with 4-point bone-borne and tooth-borne maxillary expanders.

    Science.gov (United States)

    Mosleh, Mennatallah Ihab; Kaddah, Mohamed Amgad; Abd ElSayed, Fatma Abdou; ElSayed, Hend Salah

    2015-10-01

    The purposes of this study were to evaluate and compare the dentoskeletal changes concurrent with 4-point bone-borne and tooth-borne rapid maxillary expanders in growing children. The study was conducted with 20 growing girls (ages, 12 ± 0.6 years) with posterior crossbite. They were divided into 2 equal groups; patients in one group were treated with a tooth-borne maxillary hyrax expander (TBME), and those in the other group received a bone-borne maxillary hyrax expander (BBME) anchored directly to the palatal bone. Changes were assessed using cone-beam computed tomography. Images were taken before and immediately after expansion. Superimpositions of the 3-dimensional palatal images showed significant increases in skeletal widths at the canine, first premolar, and first molar areas in both groups. The TBME group had greater nasal width expansion. Regarding the transverse dentolinear measurements, significant increases were seen in both groups, whereas the TBME group showed a greater increase than the BBME group. Significant increases in the dentoangular measurements were seen in the TBME group only and were significantly greater than in the BBME group at the first premolars. There were significant increases in facial and maxillary widths for the BBME group and in nasal width for the TBME group. Both expanders produced basal bone expansion at the level of the hard palate. The TBMEs produced more dental expansion, buccal rolling, and a greater increase in nasal width than did the BBMEs. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  11. Antibiotics for acute maxillary sinusitis

    DEFF Research Database (Denmark)

    Ahovuo-Saloranta, Anneli; Borisenko, Oleg V; Kovanen, Niina

    2008-01-01

    BACKGROUND: Expert opinions vary on the appropriate role of antibiotics for sinusitis, one of the most commonly diagnosed conditions among adults in ambulatory care. OBJECTIVES: We examined whether antibiotics are effective in treating acute sinusitis, and if so, which antibiotic classes...... are the most effective. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2007, Issue 3); MEDLINE (1950 to May 2007) and EMBASE (1974 to June 2007). SELECTION CRITERIA: Randomized controlled trials (RCTs) comparing antibiotics with placebo...... or antibiotics from different classes for acute maxillary sinusitis in adults. We included trials with clinically diagnosed acute sinusitis, whether or not confirmed by radiography or bacterial culture. DATA COLLECTION AND ANALYSIS: At least two review authors independently screened search results, extracted...

  12. Rhabdomyosarcoma of the maxillary gingiva

    Directory of Open Access Journals (Sweden)

    Mina Motallebnejad

    2018-01-01

    Full Text Available Rhabdomyosarcoma is a malignant skeletal muscle neoplasm. The tumor is much more common in children, and the most frequent site is head and neck region. Since this tumor is less frequent than other neoplasms in oral cavity, the clinicians sometimes ignore it, working the patients up. Rhabdomyosarcoma is a high-grade malignancy with poor prognosis. Considering the aggressive behavior and various clinical or histopathologic presentations of the tumor, early diagnosis has a significant impact on the treatment outcome and prognosis of the patients. We highlight the importance of combining the clinical, radiographic, and histopathologic examination to obtain a definitive diagnosis in sarcomas of the head and neck region, especially rhabdomyosarcoma. A case of rhabdomyosarcoma of the maxillary gingiva is presented in a 32-year-old woman in which the primary incisional biopsy was erroneously interpreted as an inflammatory process and consequently, the accurate diagnosis postponed for about 10 months.

  13. Os efeitos da expansão rápida da maxila sobre a permeabilidade nasal avaliados por rinomanometria e rinometria acústica The effects of rapid maxillary expansion on the nasal patency assessed by rhinomanometry and acoustic rhinometry

    Directory of Open Access Journals (Sweden)

    Bruno Alberto Vidotti

    2008-12-01

    Full Text Available O objetivo deste artigo foi analisar os achados da literatura acerca das repercussões da expansão rápida da maxila (ERM sobre a permeabilidade nasal, pela rinomanometria, que avalia a resistência oferecida pela cavidade nasal à passagem do fluxo aéreo, e pela rinometria acústica, que mede as áreas seccionais e os volumes de diferentes segmentos da cavidade nasal. Estudos que utilizaram a rinomanometria evidenciaram que a ERM determina uma diminuição significativa da resistência nasal, assim como o aumento da área de secção transversa mínima nasal (ASTM em parcela significativa de pacientes. Estudos com rinometria acústica mostraram que a ERM determina, adicionalmente, um aumento significativo do volume da cavidade nasal anterior. Entretanto, é consenso que a ERM não se justifica, por si, como forma de induzir um padrão nasal de respiração em respiradores bucais habituais, apesar dos benefícios trazidos pela ERM em termos de permeabilidade nasal.The aim of this review was to analyze the findings reported in the literature about the effects of rapid maxillary expansion (RME on nasal patency assessed by rhinomanometry, which measures the resistance offered by the nasal cavity to airflow, and acoustic rhinometry, which measures sectional areas and volumes of different segments of the nasal cavity. Studies using rhinomanometry have demonstrated a significant decrease of nasal resistance after RME on a significant number of patients, and also an increase in minimal nasal cross-sectional area. Studies using acoustic rhinometry have additionally shown a significant increase of anterior nasal volume. However, it is a consensus that RME is not justified only for the purpose of inducing a nasal pattern of breathing in oral breathers, despite the improvement of nasal patency caused by RME.

  14. Right Technology, Right Now: An Evaluation Methodology for Rapidly Deployable Information and Communications Technologies in Humanitarian Assistance/Disaster Relief

    Science.gov (United States)

    2012-03-01

    USAID U.S. Agency for International Development VPN Virtual Private Network VSAT Very Small Aperture Terminal WEP Wired Equivalent Privacy Wi-Fi...radios, satellite phones, very small aperture terminal ( VSAT ) satellite systems, personal digital assistants (PDAs), laptops, workstations, Wi-Fi...BGAN/ VSAT , respectively, as depicted in Figure 13 (Nelson, Steckler, & Stamberger, 2011). 27 Figure 13. Example of a Three Level HFN Solution

  15. Rapid identification of Mycobacterium avium clinical isolates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Lin, Chuan-Sheng; Su, Chih-Cheng; Hsieh, Shang-Chen; Lu, Chia-Chen; Wu, Tsu-Lan; Jia, Ju-Hsin; Wu, Ting-Shu; Han, Chau-Chung; Tsai, Wen-Cherng; Lu, Jang-Jih; Lai, Hsin-Chih

    2015-04-01

    Rapid and accurate discrimination of Mycobacterium avium from other mycobacteria is essential for appropriate therapeutic management and timely intervention for infection control. However, routine clinical identification methods for M. avium are both time consuming and labor intensive. In the present study, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to identify specific cellular protein pattern for rapid identification of M. avium isolates. A total of 40 clinically relevant Mycobacterium strains comprising 13 distinct species were enrolled for the MALDI-TOF MS identification. A 10-minute extraction-free examination procedure was set up to obtain mass spectral fingerprints from whole bacterial cells. The characteristic mass spectral peak patterns in the m/z (mass/charge ratio) range of 5-20 kDa can be obtained within 10 minutes. The species-specific mass spectra for M. avium is identified and can be differentiated from as Mycobacterium strains. This technique shortens and simplifies the identification procedure of MALDI-TOF MS and may further extend the mycobacterial MALDI-TOF MS database. Simplicity and rapidity of identification procedures make MALDI-TOF MS an attractive platform in routine identification of mycobacteria. MALDI-TOF MS is applicable for rapid discrimination of M. avium from other Mycobacterium species, and shows its potential for clinical application. Copyright © 2013. Published by Elsevier B.V.

  16. Microwave-assisted multicomponent reactions for rapid synthesis of AIE-active fluorescent polymeric nanoparticles by post-polymerization method.

    Science.gov (United States)

    Cao, Qian-Yong; Jiang, Ruming; Liu, Meiying; Wan, Qing; Xu, Dazhuang; Tian, Jianwen; Huang, Hongye; Wen, Yuanqing; Zhang, Xiaoyong; Wei, Yen

    2017-11-01

    The development of simple and effective methods for synthesis of fluorescent polymeric nanoparticles (FPNs) with aggregation-induced emission (AIE) plays an important role for the biomedical applications of AIE-active FPNs. In present work, we developed a facile strategy for the fabrication of AIE-active FPNs by a post-polymerization method based on the microwave-assisted Kabachnik-Fields (KF) reaction, which can conjugate with poly(PEGMA-NH2), AIE-active dye (TPE-CHO) and diethyl phosphate (DP) under microwave irradiation within 5min. The characterization results confirm that PEGMA-TPE FPNs are successfully prepared through the microwave-assisted KF reaction. The resultant AIE-active FPNs show high water dispersity, intensive fluorescence and low cytotoxicity. These features make these AIE-active FPNs great potential for biomedical applications. Moreover, the microwave-assisted KF reaction is simple, fast, atom economy that should be a general strategy for the fabrication of various multifunctional AIE-active FPNs. We believe this work will open up a new avenue for the preparation of AIE-active functional materials with great potential for different applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Managing the severely proclined maxillary anteriors by extracting traumatized right maxillary central incisor

    Directory of Open Access Journals (Sweden)

    Mahesh Jain

    2014-01-01

    Full Text Available A 14-year-old girl reported with severely proclined maxillary anterior teeth with fractured and discolored right maxillary central incisor with questionable prognosis. Autotransplantation of premolar to replace central incisor was considered a risky option as patient was 14-year-old with presence of advanced root development of premolar. The immediate placement of the prosthetic implant was also not possible because of patient′s age. Therefore, it was decided to use the space obtained by extracting questionable maxillary right central incisor for orthodontic purpose and also sacrificing the healthy premolar is invariably an excessive biological cost for a modest functional and aesthetic gain. Hence, the treatment plan for this case includes extraction of right maxillary central incisor and left maxillary first premolar, movement of right maxillary lateral incisor mesially, achieving normal axial inclination of maxillary anteriors with normal overjet and overbite. Mandibular arch was treated nonextraction due to congenitally missing central incisors with presence of normally inclined lower anteriors thereby maintaining Angles class I occlusion. Tipping, usually, seen in Begg mechanotherapy was used for our advantage to correct severely proclined maxillary anteriors with simultaneous bite opening mechanics. Case was completed in 19 months and posttreatment records including photographs, radiographs and study models were made. Begg wrap around the retainer was placed in the maxillary arch allowing natural settling of occlusion.

  18. Clinical and radiographic evaluation of maxillary central incisors exposure in patients undergoing maxillary advancement

    Directory of Open Access Journals (Sweden)

    Guilherme dos Santos Trento

    2015-12-01

    Full Text Available Abstract Introduction: Patients with dentofacial deformities may undergo orthodontic or orthodontic-surgical treatment. Both modalities can affect esthetics. Objective: This study aims to evaluate clinical and radiographic changes in exposure of maxillary central incisors occurring after orthognathic surgery for maxillary advancement. Methods: A total of 17 patients who underwent orthognathic surgery for maxillary advancement between September, 2010 and July, 2011 were selected. Exposure of maxillary central incisors was evaluated clinically and by lateral cephalograms. Measurements were taken one week before and three months after surgery. Data were paired in terms of sex, age, nasolabial angle, height and thickness of the upper lip, the amount of maxillary advancement, clinical exposure and inclination of maxillary central incisor by statistical tests (CI 95%. Results: After maxillary advancement, incisor clinical exposure had increased even with relaxed lips and under forced smile. Moreover, there was a mean increase of 23.33% revealed by lateral cephalograms. There was an inverse correlation between upper lip thickness and incisors postsurgical exposure revealed by radiographic images (p = 0.002. Conclusions: Significant changes in the exposure of maxillary central incisors occur after maxillary advancement, under the influence of some factors, especially lip thickness.

  19. Postoperative Maxillary Cyst: A Case Report

    Directory of Open Access Journals (Sweden)

    Asiye Şafak Bulut

    2010-01-01

    Full Text Available Postoperative maxillary cyst is a quite rare delayed complication of surgical intervention associated with maxillary sinuses. It occurs many years after surgery. This paper describes a 54-year-old woman presenting with swelling of left cheek for seven-years duration. The orthopantomograph revealed a unilocular cystic radiolucency with well-defined margins in left maxillary sinus. In the computerized tomography, the cyst had a sclerotic wall with bony condensations. Aspiration cytology revealed many neutrophil leukocytes. Cyst was drained and enucleated. Histopathologically, it had a fibrous wall with inflammation and focal reactive bone formation and lined by a respiratory-type epithelium. In the clinical history, it is learned that she had a maxillary sinus surgery 8 years ago and the diagnosis was made considering the clinical and histopathological findings.

  20. Determinant factors of Yemeni maxillary arch dimensions

    Directory of Open Access Journals (Sweden)

    Nabil Muhsen Al-Zubair

    2015-01-01

    Conclusion: Measurements of palatal depth and relationships of the canines to one another and to other teeth thus had the widest ranges, implying that these dimensions are the strongest determinants of maxillary arch size.

  1. Generation and evaluation of 3D digital casts of maxillary defects based on multisource data registration: A pilot clinical study.

    Science.gov (United States)

    Ye, Hongqiang; Ma, Qijun; Hou, Yuezhong; Li, Man; Zhou, Yongsheng

    2017-12-01

    Digital techniques are not clinically applied for 1-piece maxillary prostheses containing an obturator and removable partial denture retained by the remaining teeth because of the difficulty in obtaining sufficiently accurate 3-dimensional (3D) images. The purpose of this pilot clinical study was to generate 3D digital casts of maxillary defects, including the defective region and the maxillary dentition, based on multisource data registration and to evaluate their effectiveness. Twelve participants with maxillary defects were selected. The maxillofacial region was scanned with spiral computer tomography (CT), and the maxillary arch and palate were scanned using an intraoral optical scanner. The 3D images from the CT and intraoral scanner were registered and merged to form a 3D digital cast of the maxillary defect containing the anatomic structures needed for the maxillary prosthesis. This included the defect cavity, maxillary dentition, and palate. Traditional silicone impressions were also made, and stone casts were poured. The accuracy of the digital cast in comparison with that of the stone cast was evaluated by measuring the distance between 4 anatomic landmarks. Differences and consistencies were assessed using paired Student t tests and the intraclass correlation coefficient (ICC). In 3 participants, physical resin casts were produced by rapid prototyping from digital casts. Based on the resin casts, maxillary prostheses were fabricated by using conventional methods and then evaluated in the participants to assess the clinical applicability of the digital casts. Digital casts of the maxillary defects were generated and contained all the anatomic details needed for the maxillary prosthesis. Comparing the digital and stone casts, a paired Student t test indicated that differences in the linear distances between landmarks were not statistically significant (P>.05). High ICC values (0.977 to 0.998) for the interlandmark distances further indicated the high

  2. A benign maxillary tumour with malignant features.

    Science.gov (United States)

    Ricalde, Rosario R; Lim, Aimee Caroline E; Lopa, Ramon Antonio B; Carnate, Jose M

    2010-06-01

    Non-specific biopsy results such as chronic inflammation, hemorrhage, necrosis can be frustrating to the clinician. This is especially true if the patient presents with clinical features suggestive of an aggressive tumour. This is a review of the clinical features, diagnostic dilemmas and surgical management of a benign maxillary mass with malignant features - a disease called hematoma-like mass of the maxillary sinus (HLMMS). Our experience with five cases will also be cited.

  3. Detection and mapping of Cannabinoids in single hair samples through rapid derivatization- Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

    OpenAIRE

    Beasley, Emma; Francese, Simona; Bassindale, Thomas

    2016-01-01

    The sample preparation method reported in this work has permitted for the first time the application of Matrix Assisted Laser Desorption Ionization Mass Spectrometry Profiling and Imaging (MALDI-MSP and MALDI-MSI) for the detection and mapping of cannabinoids in a single hair sample. MALDI-MSI analysis of hair samples has recently been suggested as an alternative technique to traditional methods of GC-MS and LC-MS due to simpler sample preparation, the ability to detect a narrower time frame ...

  4. Microwave-assisted rapid synthesis of methyl 2,4,5-trimethoxyphenylpropionate, a metabolite of Cordia alliodora.

    Science.gov (United States)

    Sinha, A K; Joshi, B P; Sharma, A; Kumar, J K; Kaul, V K

    2003-12-01

    Microwave assisted condensation of asaronaldehyde (2) with malonic acid in piperidine-AcOH provides 2,4,5-trimethoxycinnamic acid (3) in 87% yield within 4 min, which upon further reduction with PdCl2- HCOOH-aq. NaOH gives 3-(2,4,5-trimethoxy)phenyl propionic acid (4) in 88% yield within 3 min. Esterification of 4 with MeOH-H+ gives methyl 2,4,5-trimethoxyphenylpropionate (1), a metabolite of Cordia alliodora, in 94% yield within 3 min (overall 69% yield).

  5. Rapid ultrasonic and microwave-assisted micellar extraction of zingiberone, shogaol and gingerols from gingers using biosurfactants.

    Science.gov (United States)

    Peng, Li-Qing; Cao, Jun; Du, Li-Jing; Zhang, Qi-Dong; Xu, Jing-Jing; Chen, Yu-Bo; Shi, Yu-Ting; Li, Rong-Rong

    2017-09-15

    Two kinds of extraction methods ultrasonic-assisted micellar extraction (UAME) and microwave-assisted micellar extraction (MAME) coupled with ultra-high performance liquid chromatography with ultraviolet detector (UHPLC-UV) were developed and evaluated for extraction and determination of zingerone, 6-gingerol, 8-gingerol, 6-shogaol and 10-gingerol in Rhizoma Zingiberis and Rhizoma Zingiberis Preparata. A biosurfactant, hyodeoxycholic acid sodium salt, was used in micellar extraction. Several experimental parameters were studied separately by a univariate method. The result indicated that the MAME was more efficient than UAME. The optimal conditions of MAME were as follows: 100mM of hyodeoxycholic acid sodium salt was used as surfactant, the irradiation time was set at 10s and the extraction temperature was set at 60°C. The validation results indicated that the limits of detection were in the range of 3.80-8.11ng/mL. The average recoveries were in the range of 87.32-103.12% for the two samples at two spiking levels. Compared with other reported methods, the proposed MAME-UHPLC-UV method was more effective, quicker (10s) and more eco-friendly. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Evaluation of Two Different Rapid Maxillary Expansion Surgical ...

    African Journals Online (AJOL)

    2018-02-07

    Feb 7, 2018 ... beam computed tomography, focusing on changes in soft and hard tissue in the malar region. A conventional Le Fort I .... In younger patients, conventional orthodontic RME before closure of the midpalatal suture ... disease, craniofacial deformity, or previous orthodontic treatment; SARME was included as ...

  7. Rapid canine retraction associated with maxillary sinus lifting

    OpenAIRE

    Paulo Renato Carvalho Ribeiro; Silvia Regina de Souza Monteiro; Sérgio Henrique Casarim Fernandes; Gustavo Saggioro Oliveira

    2007-01-01

    INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de 2 ou 3 semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. A técnica cirúrgica para realização deste procedimento é relativamente simples, entretanto, nos casos onde o seio maxilar apresenta-se próximo ao ápice radicular de caninos e pré-molares, sempre...

  8. Acoustic rhinometry in children undergoing a rapid maxillary expansion

    OpenAIRE

    Mario Cappellette Jr.; Daniela Carlini; Shirley Shizue Nagata Pignatari; Oswaldo Laércio Mendonça Cruz; Luc Louis Maurice Weckx

    2006-01-01

    OBJETIVO: este estudo foi realizado na Disciplina de Otorrinolaringologia Pediátrica da Escola Paulista de Medicina - UNIFESP, com o objetivo de verificar o comportamento da disjunção maxilar e sua influência na cavidade nasal em crianças de 7 a 8 anos de idade submetidas à rinometria acústica. METODOLOGIA: foram avaliadas 20 crianças respiradoras bucais, portadoras de atresia maxilar diagnosticada clinicamente e submetidas à avaliação objetiva da cavidade nasal pré-disjunção maxilar e pós-di...

  9. Stresses in the midpalatal suture in the maxillary protraction therapy: a 3D finite element analysis

    Directory of Open Access Journals (Sweden)

    Orlando M. Tanaka

    2016-03-01

    Full Text Available Abstract Background The aim of the present work was to evaluate the stress magnitudes and directions along the midpalatal suture in the maxillary protraction therapy. Methods The geometry of the maxilla and teeth were digitally reconstructed based on computer tomography images obtained from the skull of a girl in a mixed dentition stage with skeletal and dental class III malocclusion. An appliance commonly used for rapid palatal expansion (RPE was also digitally modeled for anchorage of the protraction force and meshed for finite element analysis. The maxillary protraction was simulated applying 600 cN (300 cN for each side directed 30° forward and downward to the maxillary occlusal plane. Results The principal stresses, through the force application, exhibited similar distribution patterns. A higher stress area was observed in the region of the midpalatal suture located in front of the incisive canal. All the sections showed vectors of compressive nature. Conclusions Because of the compressive nature of the stresses distributed along the midpalatal suture in the maxillary protraction therapy simulation, which is opposite to the natural growth transversal tendency, maxillary expansion is advisable in clinical cases.

  10. [Clinicopathological investigations of the dental diseases caused by maxillary lesions].

    Science.gov (United States)

    Sato, K

    1998-03-01

    Clinicopathological investigations of five surgery-requiring dental diseases caused by maxillary lesions were conducted. 1) The maxillary lesions were acute maxillary sinusitis and a postoperative maxillary cyst. 2) The clinical symptom was persistent cheek pain, even though the maxillary lesions were improved and there were no lesions in the tooth crown or periodontal tissue. 3) All of the teeth with dental diseases caused by maxillary lesions had percussion pain. 4) The pathological findings of the dental diseases were ascending pulpitis and pulpal necrosis caused by maxillary lesions. 5) When patients complain of persistent cheek pain even though maxillary lesions are improved and there are no lesions of the tooth crown or periodontal tissue, we should doubt the presence of dental diseases caused by maxillary lesions (ascending pulpitis and pulpal necrosis).

  11. Rapid Characterization of Microalgae and Microalgae Mixtures Using Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS).

    Science.gov (United States)

    Barbano, Duane; Diaz, Regina; Zhang, Lin; Sandrin, Todd; Gerken, Henri; Dempster, Thomas

    2015-01-01

    Current molecular methods to characterize microalgae are time-intensive and expensive. Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) may represent a rapid and economical alternative approach. The objectives of this study were to determine whether MALDI-TOF MS can be used to: 1) differentiate microalgae at the species and strain levels and 2) characterize simple microalgal mixtures. A common protein extraction sample preparation method was used to facilitate rapid mass spectrometry-based analysis of 31 microalgae. Each yielded spectra containing between 6 and 56 peaks in the m/z 2,000 to 20,000 range. The taxonomic resolution of this approach appeared higher than that of 18S rDNA sequence analysis. For example, two strains of Scenedesmus acutus differed only by two 18S rDNA nucleotides, but yielded distinct MALDI-TOF mass spectra. Mixtures of two and three microalgae yielded relatively complex spectra that contained peaks associated with members of each mixture. Interestingly, though, mixture-specific peaks were observed at m/z 11,048 and 11,230. Our results suggest that MALDI-TOF MS affords rapid characterization of individual microalgae and simple microalgal mixtures.

  12. Diagnosis of congenital adrenal hyperplasia by rapid determination of 17alpha-hydroxyprogesterone in dried blood spots by gas chromatography/mass spectrometry following microwave-assisted silylation.

    Science.gov (United States)

    Deng, Chunhui; Ji, Jie; Zhang, Lijuan; Zhang, Xiangmin

    2005-01-01

    17alpha-Hydroxyprogesterone (17OHP) is considered to be the biomarker of congential adrenal hyperplasia (CAH). Screening for CAH in newborns by measuring levels of the biomarker of 17OHP has become routine. In the work, a rapid, simple and sensitive technique was developed for the diagnosis of neonatal CAH by the quantitative analysis of 17OHP in neonatal blood spots. The technique was based on microwave-assisted silylation (MAS) followed by gas chromatography/mass spectrometry (GC/MS). In the method, fast derivatization of 17OHP with N,O-bis(trimethylsilyl)trifluoroacetamide was performed by using microwave irradiation, and the trimethylsilyl derivative thus formed was analyzed by GC/MS. The results of the experiment indicate that MAS followed by GC/MS analysis is a rapid, simple and sensitive method for the determination of 17OHP in blood samples. The proposed technique has been shown to have potential as a powerful tool for the rapid diagnosis of neonatal CAH. (c) 2005 John Wiley & Sons, Ltd.

  13. Rapid Characterization of Microalgae and Microalgae Mixtures Using Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS)

    Science.gov (United States)

    Barbano, Duane; Diaz, Regina; Zhang, Lin; Sandrin, Todd; Gerken, Henri; Dempster, Thomas

    2015-01-01

    Current molecular methods to characterize microalgae are time-intensive and expensive. Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) may represent a rapid and economical alternative approach. The objectives of this study were to determine whether MALDI-TOF MS can be used to: 1) differentiate microalgae at the species and strain levels and 2) characterize simple microalgal mixtures. A common protein extraction sample preparation method was used to facilitate rapid mass spectrometry-based analysis of 31 microalgae. Each yielded spectra containing between 6 and 56 peaks in the m/z 2,000 to 20,000 range. The taxonomic resolution of this approach appeared higher than that of 18S rDNA sequence analysis. For example, two strains of Scenedesmus acutus differed only by two 18S rDNA nucleotides, but yielded distinct MALDI-TOF mass spectra. Mixtures of two and three microalgae yielded relatively complex spectra that contained peaks associated with members of each mixture. Interestingly, though, mixture-specific peaks were observed at m/z 11,048 and 11,230. Our results suggest that MALDI-TOF MS affords rapid characterization of individual microalgae and simple microalgal mixtures. PMID:26271045

  14. Rapid detection of GM1 ganglioside in cerebrospinal fluid in dogs with GM1 gangliosidosis using matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Satoh, Hiroyuki; Yamauchi, Toyofumi; Yamasaki, Masahiro; Maede, Yoshimitsu; Yabuki, Akira; Chang, Hye-Sook; Asanuma, Taketoshi; Yamato, Osamu

    2011-11-01

    The concentration of GM1 (monosialotetrahexosyl ganglioside) in cerebrospinal fluid (CSF) is markedly increased in dogs with GM1 gangliosidosis due to GM1 accumulation in the central nervous system and leakage to the CSF. The present study established a rapid and simple method for detection of accumulated GM1 in the CSF in dogs with GM1 gangliosidosis using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS) and discusses the usefulness of this method for the rapid diagnosis and/or high-risk screening of this disease in domestic animals. Cerebrospinal fluid was collected from normal dogs and 4- to 11-month-old Shiba dogs with GM1 gangliosidosis. The MALDI TOF MS analysis was carried out in combination with a special sample plate and a simple desalting step on the plate. Specific signs of GM1 could be detected in the standard GM1 solutions at concentrations of 50 nmol/l or more. The signs were also clearly detected in CSF (131-618 nmol/l) in affected dogs, but not in normal canine CSF (12 ± 5 nmol/l, mean ± standard deviation). The results demonstrated that MALDI TOF MS can detect GM1 accumulated in canine CSF even in the early stage of the disease. In conclusion, the rapid detection of increased CSF GM1 using MALDI TOF MS is a useful method for diagnosis and/or screening for canine GM1 gangliosidosis.

  15. Rapid discrimination of environmental Vibrio by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Eddabra, Rkia; Prévost, Gilles; Scheftel, Jean-Michel

    2012-04-20

    The aim of this study was to discriminate 30 Vibrio strains isolated from two wastewater treatment plants from Agadir, Morocco by two molecular typing methods, pulsed-field gel electrophoresis (PFGE) and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Out of the 30 strains of Vibrio examined in this study, 5 isolates could not be typed by PFGE and consistently appeared as a smear on the gel. In general, high genetic biodiversity among the Vibrio strains was found regardless to the isolation source. The results of MALDI TOF analysis show a high congruence of strain grouping demonstrating the accuracy and reliability of MALDI-TOF MS. Copyright © 2011 Elsevier GmbH. All rights reserved.

  16. Homogenization and texture development in rapidly solidified AZ91E consolidated by Shear Assisted Processing and Extrusion (ShAPE)

    Energy Technology Data Exchange (ETDEWEB)

    Overman, N. R.; Whalen, S. A.; Bowden, M. E.; Olszta, M. J.; Kruska, K.; Clark, T.; Stevens, E. L.; Darsell, J. T.; Joshi, V. V.; Jiang, X.; Mattlin, K. F.; Mathaudhu, S. N.

    2017-07-01

    Shear Assisted Processing and Extrusion (ShAPE) -a novel processing route that combines high shear and extrusion conditions- was evaluated as a processing method to densify melt spun magnesium alloy (AZ91E) flake materials. This study illustrates the microstructural regimes and transitions in crystallographic texture that occur as a result of applying simultaneous linear and rotational shear during extrusion. Characterization of the flake precursor and extruded tube was performed using scanning and transmission electron microscopy, x-ray diffraction and microindentation techniques. Results show a unique transition in the orientation of basal texture development. Despite the high temperatures involved during processing, uniform grain refinement and material homogenization are observed. These results forecast the ability to implement the ShAPE processing approach for a broader range of materials with novel microstructures and high performance.

  17. Microwave assisted rapid growth of Mg(OH){sub 2} nanosheet networks for ethanol chemical sensor application

    Energy Technology Data Exchange (ETDEWEB)

    Al-Hazmi, Faten [Department of Physics, College of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21569 (Saudi Arabia); Umar, Ahmad, E-mail: ahmadumar786@gmail.com [Promising Centre for Sensors and Electronic Devices (PCSED) and Centre for Advanced Materials and Nano-Research (CAMNR), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Dar, G.N. [Promising Centre for Sensors and Electronic Devices (PCSED) and Centre for Advanced Materials and Nano-Research (CAMNR), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Al-Ghamdi, A.A.; Al-Sayari, S.A. [Department of Physics, College of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21569 (Saudi Arabia); Al-Hajry, A. [Promising Centre for Sensors and Electronic Devices (PCSED) and Centre for Advanced Materials and Nano-Research (CAMNR), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Department of Physics, College of Science and Arts, Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Kim, S.H. [Promising Centre for Sensors and Electronic Devices (PCSED) and Centre for Advanced Materials and Nano-Research (CAMNR), Najran University, P.O. Box 1988, Najran 11001 (Saudi Arabia); Al-Tuwirqi, Reem M. [Department of Physics, College of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21569 (Saudi Arabia); Alnowaiserb, Fowzia [Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah (Saudi Arabia); El-Tantawy, Farid [Department of Physics, Faculty of Science, Suez Canal University, Ismailia (Egypt)

    2012-04-05

    Highlights: Black-Right-Pointing-Pointer A facile microwave-assisted synthesis and characterizations of magnesium hydroxide (Mg(OH){sub 2}) nanosheet networks. Black-Right-Pointing-Pointer Fabrication of ethanol sensor based on (Mg(OH){sub 2}) nanosheet networks. Black-Right-Pointing-Pointer Good sensitivity ({approx}3.991 {mu}A cm{sup -2} mM{sup -1}) and lower detection limit (5 {mu}M). Black-Right-Pointing-Pointer This research opens a way to utilize Mg(OH){sub 2} nanostructures for chemical sensors applications. - Abstract: This paper reports a facile microwave-assisted synthesis of magnesium hydroxide (Mg(OH){sub 2}) nanosheet networks and their utilization for the fabrication of efficient ethanol chemical sensor. The synthesized nanosheets networks were characterized in terms of their morphological, structural and optical properties using various analysis techniques such as field emission scanning electron microscopy (FESEM), X-ray diffraction pattern (XRD), Fourier transform infrared (FTIR) and UV-Vis spectroscopy. The detailed morphological and structural investigations reveal that the synthesized (Mg(OH){sub 2}) products are nanosheet networks, grown in high density, and possessing hexagonal crystal structure. The optical band gap of as-synthesized Mg(OH){sub 2} nanosheet networks was examined by UV-Vis absorption spectrum, and found to be 5.76 eV. The synthesized nanosheet networks were used as supporting matrices for the fabrication of I-V technique based efficient ethanol chemical sensor. The fabricated ethanol sensor based on nanosheet networks exhibits good sensitivity ({approx}3.991 {mu}A cm{sup -2} mM{sup -1}) and lower detection limit (5 {mu}M), with linearity (R = 0.9925) in short response time (10.0 s). This work demonstrate that the simply synthesized Mg(OH){sub 2} nanosheet networks can effectively be used for the fabrication of efficient ethanol chemical sensors.

  18. Continuous, size and shape-control synthesis of hollow silica nanoparticles enabled by a microreactor-assisted rapid mixing process

    Science.gov (United States)

    He, Yujuan; Kim, Ki-Joong; Chang, Chih-Hung

    2017-06-01

    Hollow silica nanoparticles (HSNPs) were synthesized using a microreactor-assisted system with a hydrodynamic focusing micromixer. Due to the fast mixing of each precursor in the system, the poly(acrylic acid) (PAA) thermodynamic-locked (TML) conformations were protected from their random aggregations by the immediately initiated growth of silica shells. When altering the mixing time through varying flow rates and flow rate ratios, the different degrees of the aggregation of PAA TML conformations were observed. The globular and necklace-like TML conformations were successfully captured by modifying the PAA concentration at the optimized mixing condition. Uniform HSNPs with an average diameter ∼30 nm were produced from this system. COMSOL numerical models was established to investigate the flow and concentration profiles, and their effects on the formation of PAA templates. Finally, the quality and utility of these uniform HSNPs were demonstrated by the fabrication of antireflective thin films on monocrystalline photovoltaic cells which showed a 3.8% increase in power conversion efficiency.

  19. Rapid adsorption properties of flower-like BiOI nanoplates synthesized via a simple EG-assisted solvothermal process

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Bin; Ji, Guangbin, E-mail: gbji@nuaa.edu.cn [Nanjing University of Aeronautics and Astronautics, College of Materials Science and Technology (China); Gondal, M. A. [King Fahd University of Petroleum and Minerals, Physics Department (Saudi Arabia); Liu, Yousong; Zhang, Xingmiao; Chang, Xiaofeng; Li, Nianwu [Nanjing University of Aeronautics and Astronautics, College of Materials Science and Technology (China)

    2013-07-15

    Uniform well-crystallized flower-like BiOI nanoplates contained 3.7 nm mesopores, which may be attributed to the internanosheet spaces of BiOI with maximum pore diameters of about 30 nm, were successfully synthesized via a simple ethylene glycol-assisted solvothermal method. The as-prepared porous BiOI nanoplates exhibited excellent adsorption ability, and the saturated extent of adsorption of BiOI over an RhB solution was as high as 197 mg/g, which is much higher than those for BiOCl and BiOBr prepared via the same method and with a similar surface area. The probable adsorption mechanism could have originated from the interaction between the I atom in BiOI and a proton in RhB at different pH values and temperatures. With visible light irradiation ({lambda} > 420 nm), 80 % of the RhB was degraded in 4 h, while BiOI still demonstrated reasonably outstanding photocatalytic ability under green light ({lambda} = 550 {+-} 15 nm) because of its low-energy gap (1.72 eV). The degradation test for BiOI under irradiation at {lambda} = 550 {+-} 15 nm is an excellent achievement for field applications because the catalyst can be applied in solar irradiation to remove organic pollutants, which may be of great value BiOI complex.

  20. Foreign body of endodontic origin in the maxillary sinus

    Directory of Open Access Journals (Sweden)

    Marta Tanasiewicz

    2017-09-01

    Full Text Available Foreign bodies found in the maxillary sinus include tooth roots, burs, dental impression material, root-filling materials, dental implants, and needles. The purpose of this paper was to present an unusual case of a large foreign body of endodontic origin (root-filling material removed from the maxillary sinus. A 45-year-old generally healthy male patient reported to the Department of Conservative Dentistry with Endodontics of the Medical University of Silesia, because of orbital and buccal pain on the right side of his face and headaches in the preceding 6 months. Those symptoms were associated with the end of endodontic treatment of teeth 14 and 16. Periapical X-rays, including of teeth 14 and 16, showed the presence of root canal filling with extrusion of endodontic obturation material beyond the apices of tooth 14. In the case of tooth 16, a completely filled palatal canal and incompletely filled buccal canals were found. There was also an irregular dimness at the upper edge of the X-ray image. Panoramic radiography and computed tomography demonstrated a foreign body in the right sinus. Sinus exploration was performed via a surgical procedure conducted using topical anesthesia. The root apices of tooth 14 were resected, and foreign substance was removed. The practitioner did not correctly recognize a complication that occurred during endodontic treatment, which resulted in extrusion of endodontic material beyond the root apices of tooth 14. This case emphasizes the potential impact that an involved maxillary sinus may have on endodontic therapy. Detailed diagnostic identification based on the medical interview, physical and histopathological examinations, and diagnostic imaging allowed rapid surgical intervention and prevented local and general complications. It is important to realize that the range of the periapical X-ray projection is not always sufficient.

  1. Rapid and ultrasensitive detection of microRNA by target-assisted isothermal exponential amplification coupled with poly (thymine)-templated fluorescent copper nanoparticles

    Science.gov (United States)

    Park, Kwan Woo; Batule, Bhagwan S.; Kang, Kyoung Suk; Park, Ki Soo; Park, Hyun Gyu

    2016-10-01

    We devised a novel method for rapid and ultrasensitive detection of target microRNA (miRNA) by employing target-assisted isothermal exponential amplification (TAIEA) combined with poly (thymine)-templated fluorescent copper nanoparticles (CuNPs) as signaling probes. The target miRNA hybridizes to the unimolecular template DNA and works as a primer for the extension reaction to form double-stranded product, which consequently generates two nicking endonuclease recognition sites. By simultaneous nicking and displacement reactions, exponential amplification generates many poly (thymine) strands as final products, which are employed for the synthesis of fluorescent CuNPs. Based on the fluorescent signal from CuNPs, target miRNA is detected as low as 0.27 fM around 1 h of total analysis time. The diagnostic capability of this system has been successfully demonstrated by reliably detecting target miRNA from different cell lysates, showing its great potential towards real clinical applications.

  2. Rapid detection of porins by matrix-assisted laser desorption/ionization-time of flight mass spectrometry

    Directory of Open Access Journals (Sweden)

    Yanyan eHU

    2015-08-01

    Full Text Available The rapid and cost-efficient determination of carbapenem resistance is an important prerequisite for the choice of an adequate antibiotic therapy. A MALDI-TOF MS-based assay was set up to detect porins in the current study. A loss of the components of porin alone such as OmpK35/OmpK36 or together with the production of carbapenemases will augment the carbapenem resistance. Ten strains of E. coli and eight strains of K. pneumoniae were conducted for both SDS-PAGE and MALDI-TOF MS analysis. MALDI-TOF/TOF MS analysis was then performed to verify the corrospondence of proteins between SDS-PAGE and MALDI-TOF MS. The results indicated that the mass spectrum of ca. 35,000-m/z, 37,000-m/z and 38,000-m/z peaks of E. coli ATCC 25922 corresponded to OmpA, OmpC and OmpF with molecular weight of approximately ca. 38 kDa, 40 kDa and 41 kDa in SDS-PAGE gel, respectively. The band of OmpC and OmpF porins were unable to be distinguished by SDS-PAGE, whereas it was easy to be differentiated by MALDI-TOF MS. As for K. pneumoniae isolates, the mass spectrum of ca. 36,000-m/z and 38,600-m/z peaks was observed corresponding to OmpA and OmpK36 with molecular weight of approximately ca. 40 kDa and 42 kDa in SDS-PAGE gel, respectively. Porin OmpK35 was not observed in the current SDS-PAGE, while a 37,000-m/z peak was found in K. pneumoniae ATCC 13883 and carbapenem-susceptible strains by MALDI-TOF MS which was presumed to be the characteristic peak of the OmpK35 porin. Compared with SDS-PAGE, MALDI-TOF MS is able to rapidly identify the porin-deficient strains within half an hour with better sensitivity, less cost, and is easier to operate and has less interference.

  3. Rapid identification of siderophores by combined thin-layer chromatography/matrix-assisted laser desorption/ionization mass spectrometry.

    Science.gov (United States)

    Hayen, Heiko; Volmer, Dietrich A

    2005-01-01

    The investigation of a combined thin-layer chromatography/matrix-assisted laser desorption/ionization mass spectrometry (TLC/MALDI-MS) method for the analysis of siderophores from microbial samples is described. The investigated siderophores were enterobactin, ferrioxamine B, ferrichrome, ferrirhodin, rhodotorulic acid and coprogen. Solid-phase extraction was employed to recover the siderophores from the microbial samples. After visualization of the spots via spraying with ferric chloride or chrome azurol sulfonate assay solution, the MALDI matrix was applied to the gel surface. Several TLC/MALDI experimental parameters were optimized, such as type and concentration of MALDI matrix, as well as the type and composition of solvent to facilitate analyte transport from the inside of the TLC gel to the surface. The impact of these parameters on sensitivity, precision and ion formation of the various siderophores was studied. The detection limits for the investigated siderophores were in the range 1-4 pmol. These values were about 4-24 times higher than the detection limits obtained directly from stainless steel MALDI targets. The differences were most likely due to incomplete transport of the 'trapped' analyte molecules from the deeper layers of the TLC gel to the surface and into the matrix layer. In addition, chromatographic band broadening spread the analyte further in TLC as compared with the steel plates, resulting in less analyte per surface area. The identification of the siderophores was aided by concurrently applying a Ga(III) nitrate solution to the TLC plate during the visualization step. The resulting formation of Ga(III) complexes lead to distinctive (69)Ga/(71)Ga isotope patterns in the mass spectra. The versatility of the TLC/MALDI-MS assay was demonstrated by using it to analyze siderophores in a Pseudomonas aeruginosa sample. An iron-binding compound was identified in the sample, namely pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3

  4. Ultrasonic-assisted Kabachnik-Fields reaction for rapid fabrication of AIE-active fluorescent organic nanoparticles.

    Science.gov (United States)

    Long, Zi; Liu, Meiying; Jiang, Ruming; Zeng, Guangjiang; Wan, Qing; Huang, Hongye; Deng, Fengjie; Wan, Yiqun; Zhang, Xiaoyong; Wei, Yen

    2017-03-01

    Aggregation-induced emission (AIE)-active fluorescent organic nanoparticles (FNPs) have been extensively explored for fluorescence "turn-on" bio-imaging applications with the unique advantages over conventional FNPs. Transformation of AIE-active molecules into FNPs can greatly expand their biomedical application potential. Here we reported a novel "one-pot" strategy for fabricating AIE-active FNPs through an ultrasonic-assisted, catalysts-free and solvent-free Kabachnik-Fields (KF) reaction for the first time. The KF reaction can be completed within 10min to generate AIE-active PTH-CHO-PEI-DEP FNPs through mixing polyethylenimine and aldehyde group containing AIE dyes and diethyl phosphate. These PTH-CHO-PEI-DEP FNPs were confirmed by proton nuclear magnetic resonance ((1)H NMR) spectroscopy, transmission electron microscopy (TEM) and fluorescence spectroscopy etc. The cell uptake behavior as well as cell viability of PTH-CHO-PEI-DEP FNPs was examined to evaluate their potential for biomedical application. We demonstrated that the amphiphilic α-aminophosphonate polymers could self-assemble into PTH-CHO-PEI-DEP FNPs in aqueous solution and showed excellent water dispersibility. TEM image shows the size of PTH-CHO-PEI-DEP FNPs is 100-200nm. More importantly, the PTH-CHO-PEI-DEP FNPs emit strong green fluorescence and desirable biocompatibility, making them very suitable for biomedical applications. Finally, thus smart FNPs design together with their excellent performance will open a new avenue in the development of FNPs for following biological processes such as carcinogenesis. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. A simple and rapid infrared-assisted self enzymolysis extraction method for total flavonoid aglycones extraction from Scutellariae Radix and mechanism exploration.

    Science.gov (United States)

    Wang, Liping; Duan, Haotian; Jiang, Jiebing; Long, Jiakun; Yu, Yingjia; Chen, Guiliang; Duan, Gengli

    2017-09-01

    A new, simple, and fast infrared-assisted self enzymolysis extraction (IRASEE) approach for the extraction of total flavonoid aglycones (TFA) mainly including baicalein, wogonin, and oroxylin A from Scutellariae Radix is presented to enhance extraction yield. Extraction enzymolysis temperature, enzymolysis liquid-to-solid ratio, enzymolysis pH, enzymolysis time and infrared power, the factors affecting IRASEE procedure, were investigated in a newly designed, temperature-controlled infrared-assisted extraction (TC-IRAE) system to acquire the optimum analysis conditions. The results illustrated that IRASEE possessed great advantages in terms of efficiency and time compared with other conventional extraction techniques. Furthermore, the mechanism of IRASEE was preliminarily explored by observing the microscopic change of the samples surface structures, studying the main chemical compositions change of the samples before and after extraction and investigating the kinetics and thermodynamics at three temperature levels during the IRASEE process. These findings revealed that IRASEE can destroy the surface microstructures to accelerate the mass transfer and reduce the activation energy to intensify the chemical process. This integrative study presents a simple, rapid, efficient, and environmental IRASEE method for TFA extraction which has promising prospects for other similar herbal medicines. Graphical Abstract ᅟ.

  6. Expansão maxilar em adultos e adolescentes com maturação esquelética avançada Maxillary expansion in adults and adolescents with advanced skeletal maturation

    Directory of Open Access Journals (Sweden)

    Rowdley Robert Pereira Rossi

    2009-10-01

    situations Surgically Assisted Rapid Maxillary Expansion (SARME can be an option. And the choice of the surgical technique (SARME should focus mainly the patient's age, grade of skeletal maturation, anatomical structures that offer more resistance to the maxillary expansion and location of the palatal constriction. Hyrax is the expander appliance more indicated for patients that will be submitted to SARME.

  7. Several early interventions for ectopic maxillary canines.

    Directory of Open Access Journals (Sweden)

    Carlos Astorga

    2012-07-01

    Full Text Available Maxillary canine impactation is often encountered in orthodontic clinical practice and the aetiology is associated to genetic factors as well as local space factors. If preventive treatment is not started in ectopic maxillary canines, some possible consequences may occur, such as resorption of the roots of the neighboring permanent teeth, cysts, ankylosis and expensive surgical and orthodontic treatment. The aim of this review was to preset several early treatment modalities for ectopic maxillary canines based on recent scientific evidence. Four are the most important: Only extractions intervention, extraction of deciduous canines with cervical pull headgear, active intervention in late mixed dentition and active intervention in early mixed dentition. These different modalities showed a greater increasing the rate of normal eruption of ectopic canines ( 80-97%. The extraction of primary canine alone is still an effective method to prevent canine impactation, whose success rate would be increased if some other method interceptive is added.

  8. Management of missing maxillary lateral incisors.

    Science.gov (United States)

    Sabri, R

    1999-01-01

    Missing maxillary lateral incisors create an esthetic problem with specific orthodontic and prosthetic considerations. The purpose of this article is to describe treatment protocols and problems encountered in the management of this disorder. The two common treatment options are orthodontic space opening for future restorations or orthodontic space closure using canines to replace the missing maxillary lateral incisors. The required amount of space opening and the various prosthetic options are discussed. The methods for reshaping canines in orthodontic space closure and building them up to simulate lateral incisors also are described. The indications, advantages and disadvantages of both treatment modalities are outlined to help clinicians make decisions in borderline situations. Teamwork between the orthodontist, general practitioner and restorative dentist is important when analyzing factors related to individual patients and establishing overall treatment plans. This also will allow treatment modalities and the various options for replacing missing maxillary lateral incisors in space opening to be discussed between team members and the patient.

  9. Unusual case of bilateral maxillary fungus ball.

    Science.gov (United States)

    Vinciguerra, Alessandro; Saibene, Alberto Maria; Lozza, Paolo; Maccari, Alberto

    2016-12-15

    An otherwise healthy 34-year-old man was referred to our ear, nose and throat (ENT) clinic for a bilateral maxillary radiologic opacity. This condition was accidentally discovered with a panoramic radiography performed during a follow-up visit after a bilateral endodontic treatment. The patient did not report any specific sinonasal symptom such as purulent nasal discharge, loss of smell and cough, apart from an unspecific sinus pressure. The CT scans showed a bilateral inflammatory process into the maxillary-ethmoidal sinuses and an iron-like density within the maxillary sinuses, while nasal endoscopy showed purulent discharge in the ostiomeatal complex. The patient underwent functional endoscopic sinus surgery under general anaesthesia and the inflammatory material collected was histologically diagnosed as a rare case of bilateral fungus ball. The patient was dismissed the following day with no complications; there were not any sign of recurrence or symptoms during a 4 month follow-up. 2016 BMJ Publishing Group Ltd.

  10. Rare occurrence of the left maxillary horizontal third molar impaction ...

    African Journals Online (AJOL)

    Rare occurrence of the left maxillary horizontal third molar impaction, the right maxillary third molar vertical impaction and the left mandibular third molar vertical impaction with inferior alveolar nerve proximity in a 30 year old female: a case report.

  11. Craniofacial morphological differences between Down syndrome and maxillary deficiency children

    National Research Council Canada - National Science Library

    Silva Jesuino, Flávia Aline; Valladares-Neto, José

    2013-01-01

    Maxillary deficiency is one of the facial features of Down syndrome (DS). Differences in craniofacial morphology between DS and nonsyndromic skeletal Class III malocclusion with maxillary deficiency remain unclear...

  12. An unusual foreign body in the maxillary sinus: Dental impression ...

    African Journals Online (AJOL)

    2015-03-06

    12] The present report presents a case of dental impression material that passed through an oro‑antral fistula while in its plastic form, solidified inside the maxillary sinus, and caused a maxillary sinus infection. Case Report.

  13. Maxillary palp glomeruli and ipsilateral projections in the antennal ...

    Indian Academy of Sciences (India)

    Unknown

    seven) reported to be expressed exclusively in the maxillary palp. ... maxillary palp sensory neurons but specified only glo- meruli VA4, VA3 and DM2 to ..... Neuronal architecture of the antennal lobe in Drosophila mela- nogaster; Cell Tissue Res.

  14. Comparison of rapidly synergistic cloud point extraction and ultrasound-assisted cloud point extraction for trace selenium coupled with spectrophotometric determination.

    Science.gov (United States)

    Wen, Xiaodong; Zhang, Yanyan; Li, Chunyan; Fang, Xiang; Zhang, Xiaocan

    2014-04-05

    In this work, rapidly synergistic cloud point extraction (RS-CPE) and ultrasound-assisted cloud point extraction (UA-CPE) were firstly compared and coupled with spectrophotometer for selenium preconcentration and detection. The established RS-CPE pretreatment was simple, rapid and high effective. The extraction time was only 1min without heating process. Under the effect of ultrasound, UA-CPE accomplished extraction efficiently although the extraction procedure was relatively time-consuming. In this study, RS-CPE and UA-CPE were firstly applied for selenium preconcentration and coupled with conventional spectrophotometer. Their applications were expanded and the analytical performance of spectrophotometric determination for selenium was considerably improved. The influence factors relevant to RS-CPE and UA-CPE were studied in detail. Under the optimal conditions, the limits of detection (LODs) for selenium were respectively 0.2μgL(-1) of RS-CPE and 0.3μgL(-1) of UA-CPE with sensitivity enhancement factors (EFs) of 124 and 103. The developed methods were applied to the determination of trace selenium in real water samples with satisfactory analytical results. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. A simple method for rapid microbial identification from positive monomicrobial blood culture bottles through matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Lin, Jung-Fu; Ge, Mao-Cheng; Liu, Tsui-Ping; Chang, Shih-Cheng; Lu, Jang-Jih

    2017-06-30

    Rapid identification of microbes in the bloodstream is crucial in managing septicemia because of its high disease severity, and direct identification from positive blood culture bottles through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can shorten the turnaround time. Therefore, we developed a simple method for rapid microbiological identification from positive blood cultures by using MALDI-TOF MS. We modified previously developed methods to propose a faster, simpler and more economical method, which includes centrifugation and hemolysis. Specifically, our method comprises two-stage centrifugation with gravitational acceleration (g) at 600g and 3000g, followed by the addition of a lysis buffer and another 3000g centrifugation. In total, 324 monomicrobial bacterial cultures were identified. The success rate of species identification was 81.8%, which is comparable with other complex methods. The identification success rate was the highest for Gram-negative aerobes (85%), followed by Gram-positive aerobes (78.2%) and anaerobes (67%). The proposed method requires less than 10 min, costs less than US$0.2 per usage, and facilitates batch processing. We conclude that this method is feasible for clinical use in microbiology laboratories, and can serve as a reference for treatments or further complementary diagnostic testing. Copyright © 2017. Published by Elsevier B.V.

  16. Rapid Ag/Sn/Ag transient liquid phase bonding for high-temperature power devices packaging by the assistance of ultrasound.

    Science.gov (United States)

    Shao, Huakai; Wu, Aiping; Bao, Yudian; Zhao, Yue; Liu, Lei; Zou, Guisheng

    2017-07-01

    Rapid transient liquid phase (TLP) bonding process on Ag/Sn/Ag system is achieved in air by the assistance of ultrasonic, which has great potential to be applied to high-temperature power devices packaging. In this study, the influence of ultrasonic effect on the morphology and growth kinetics of Ag3Sn grains, and the joint microstructure, mechanical property and thermal reliability were systematically investigated. Experimental results indicated that the rapid consumption of the "dynamic" transient liquid phase was attributed to the accelerated dissolution of Ag substrate and the extrusion of liquid Sn, which were entirely induced by the complex sonochemical effects on the liquid/solid intermetallic compounds (IMCs) interface. An elongated scallop-like morphology of Ag3Sn grains was developed during Ag/Sn interfacial reaction with ultrasonic, accompanied by widening of grooves between neighbored grains. This phenomenon is called as a strengthening thermal grooving, in which the grooves at grain boundaries provide stable molten channels for Ag atoms diffusion from the substrate. Consequently, the improved elemental diffusion was evaluated through the growth kinetics of Ag3Sn IMCs, with conservative estimation of 6-16.5 times faster than the traditional TLP process. In addition, both excellent mechanical property and thermal reliability of the Ag-Sn intermetallic joint were experimentally verified by shear test and high-temperature storage test, respectively. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Rapid determination of oxindole alkaloids in cat's claw by HPLC using ionic liquid-based microwave-assisted extraction and silica monolithic column.

    Science.gov (United States)

    Chang, Chih-Wei; Yeh, Yu-Ying; Chang, Li-Ching; Hsu, Mei-Chich; Wu, Yu-Tse

    2017-08-01

    Cat's claw is a large woody vine with hook-like thorns, and has been traditionally used to treat inflammatory disorders in South and Central America. In this study, a rapid, validated high-performance liquid chromatographic (HPLC) method using a silica monolithic column was developed for the simultaneous determination of oxindole alkaloids, namely rhynchophylline, pteropodine, isomitraphylline and isopteropodine, in cat's claw. The ionic liquid-based microwave-assisted extraction (ILMAE), considered as an environmentally friendly and powerful tool, was first applied in the extraction of oxindole alkaloids. To optimize the HPLC method, the stationary phases, pH values of mobile phase and flow rates were investigated. The validated HPLC method using a Monolithic RP18e column (100 × 4.6 mm) enables these analytes to be separated almost twice as fast as with a conventional particulate column (~16 vs ~30 min) with limits of quantification and detection of 0.5 and 0.15 μg/mL, respectively. The ILMAE conditions were optimized by the Taguchi orthogonal array design. In comparison with conventional water boiling extraction, ILMAE offers almost four times higher yields within an extremely short extraction time. The developed HPLC coupled with ILMAE method could be efficient and practical for rapid determination of oxindole alkaloids in cat's claw. Copyright © 2016 John Wiley & Sons, Ltd.

  18. Rapid determination of volatile constituents in safflower from Xinjiang and Henan by ultrasonic-assisted solvent extraction and GC–MS

    Science.gov (United States)

    Jia, Ling-Han; Liu, Yi; Li, Yu-Zhen

    2011-01-01

    The total volatile components were extracted from safflower by ultrasonic-assisted solvent extraction (USE) and their chemical constituents were analyzed by gas chromatography–mass spectrometry (GC–MS) to provide scientific basis for the quality control of safflower. Five different solvents (diethyl ether, ethanol, ethyl acetate, dichloromethane and acetone) were used and compared in terms of number of volatile components extracted and the peak areas of these components in TIC. The results showed that USE could be used as an efficient and rapid method for extracting the volatile components from safflower. It also could be found that the number of components in the TIC of ethyl acetate extract was more than that in the TIC of other solvent ones. Meanwhile, the volatile components of safflower from Xinjiang Autonomous Region and Henan Province of China were different in chemical components and relative contents. It could be concluded that both the extraction solvents and geographical origin of safflower are responsible for these differences. The experimental results also indicated that USE/GC–MS is a simple, rapid and effective method to analyze the volatile oil components of safflower.

  19. Rapid determination of volatile constituents in safflower from Xinjiang and Henan by ultrasonic-assisted solvent extraction and GC–MS

    Directory of Open Access Journals (Sweden)

    Ling-Han Jia

    2011-08-01

    Full Text Available The total volatile components were extracted from safflower by ultrasonic-assisted solvent extraction (USE and their chemical constituents were analyzed by gas chromatography–mass spectrometry (GC–MS to provide scientific basis for the quality control of safflower. Five different solvents (diethyl ether, ethanol, ethyl acetate, dichloromethane and acetone were used and compared in terms of number of volatile components extracted and the peak areas of these components in TIC. The results showed that USE could be used as an efficient and rapid method for extracting the volatile components from safflower. It also could be found that the number of components in the TIC of ethyl acetate extract was more than that in the TIC of other solvent ones. Meanwhile, the volatile components of safflower from Xinjiang Autonomous Region and Henan Province of China were different in chemical components and relative contents. It could be concluded that both the extraction solvents and geographical origin of safflower are responsible for these differences. The experimental results also indicated that USE/GC–MS is a simple, rapid and effective method to analyze the volatile oil components of safflower. Keywords: Safflower, Ultrasonic solvent extraction, Gas chromatography–mass spectrometry (GC–MS

  20. Rapid identification of clinical mycobacterial isolates by protein profiling using matrix assisted laser desorption ionization-time of flight mass spectrometry.

    Science.gov (United States)

    Panda, A; Kurapati, S; Samantaray, J C; Myneedu, V P; Verma, A; Srinivasan, A; Ahmad, H; Behera, D; Singh, U B

    2013-01-01

    The purpose of this study was to evaluate the identification of Mycobacterium tuberculosis which is often plagued with ambiguity. It is a time consuming process requiring 4-8 weeks after culture positivity, thereby delaying therapeutic intervention. For a successful treatment and disease management, timely diagnosis is imperative. We evaluated a rapid, proteomic based technique for identification of clinical mycobacterial isolates by protein profiling using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Freshly grown mycobacterial isolates were used. Acetonitrile/trifluoroacetic acid extraction procedure was carried out, following which cinnamic acid charged plates were subjected to identification by MALDI-TOF MS. A comparative analysis of 42 clinical mycobacterial isolates using the MALDI-TOF MS and conventional techniques was carried out. Among these, 97.61% were found to corroborate with the standard methods at genus level and 85.36% were accurate till the species level. One out of 42 was not in accord with the conventional assays because MALDI-TOF MS established it as Mycobacterium tuberculosis (log (score)>2.0) and conventional methods established it to be non-tuberculous Mycobacterium. MALDI-TOF MS was found to be an accurate, rapid, cost effective and robust system for identification of mycobacterial species. This innovative approach holds promise for early therapeutic intervention leading to better patient care.

  1. Ionic-liquid-assisted microwave distillation coupled with headspace single-drop microextraction followed by GC-MS for the rapid analysis of essential oil in Dryopteris fragrans.

    Science.gov (United States)

    Jiao, Jiao; Gai, Qing-Yan; Wang, Wei; Luo, Meng; Zhao, Chun-Jian; Fu, Yu-Jie; Ma, Wei

    2013-12-01

    A rapid, green and effective miniaturized sample preparation technique, ionic-liquid-assisted microwave distillation coupled with headspace single-drop microextraction was developed for the extraction of essential oil from dried Dryopteris fragrans. 1-Ethyl-3-methylimidazolium acetate was the optimal ionic liquid as the destruction agent of plant cell walls and microwave absorption was medium. n-Heptadecane (2.0 μL) was adopted as the suspended microdrop solvent in the headspace for the extraction and concentration of essential oil. The optimal parameters of the proposed method were an irradiation power of 300 W, sample mass of 0.9 g, mass ratio of ionic liquids to sample of 2.8, extraction temperature of 79°C, and extraction time of 3.6 min. In comparison to the previous reports, the proposed technique could equally monitor all the essential oil components with no significant differences in a simple way, which was more rapid and required a much lower amount of sample. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Maxillary Corticotomies With Bone-to-Bone Retraction and Mandibular Segmental Osteotomy for Correcting an Anterior Double Protrusion.

    Science.gov (United States)

    Kim, Kyung A; Lee, Baek-Soo; Akbulut, Ayse Selenge; Kim, Seong-Hun; Nelson, Gerald

    2017-11-01

    This article presents maxillary corticotomies with bone-to-bone retraction and anterior segmental osteotomy (ASO) as an alternative to 2-jaw orthognathics in the bimaxilary protrusion patient with partially anchylosed maxillary anterior tooth. The 18-year-old male, complaining of anterior protrusion, with a trauma history to the maxillary central incisor, and requesting rapid treatment, was treated with maxillary corticotomies in 2 stages and ASO in the mandible. The mandibular ASO and palatal corticotomy were done under local anesthesia and 2 weeks later, labial corticotomy followed. The anterior segment was retracted bodily using buccal C-tubes and a combination of the C-lingual retractor and palatal C-plate. Due to a concern about ankylosis of the maxillary right central incisor, retraction of the anterior bone/tooth segment was chosen over any attempt to move teeth through the bone. After bone-to-bone retraction, the remaining extraction space was closed by protraction of posteriors. The total treatment period was 18 months. There was good retraction of the anterior segment and retrusion of the lips. A combination of maxillary corticotomies with skeletal anchorage for bone-to-bone retraction and a mandibular ASO under local anesthesia might be an alternative treatment option for excellent profile change in a short treatment period.

  3. Large radicular cyst in the maxillary sinus.

    Science.gov (United States)

    Sagit, Mustafa; Guler, Sabri; Tasdemir, Arzu; Akf Somdas, Mehmet

    2011-11-01

    Radicular cysts (RCs) are the most common inflammatory jaw cystic lesions that occur infected and necrotic in teeth pulps. They account for more than 50% of all odontogenic cysts. Radicular cysts cause slowly progressive painless swelling. There are no symptoms until they become large. Enucleating the cyst is recommended with primary treatment. Here we describe a patient with a large RC with maxillary sinus involvement who underwent an endonasal endoscopic approach for complete resection. In conclusion, the endonasal endoscopic approach should be kept in mind for the resection of RC with maxillary sinus involvement because of its minimally invasive characteristics.

  4. [Evaluation of the speech outcomes in patients with unilateral maxillary defect rehabilitated with maxillary obturator prosthesis].

    Science.gov (United States)

    Xing, Guo-fang; Jiao, Ting; Sun, Jian; Jiang, Yong-lin

    2005-08-01

    Evaluation of the outcomes in 15 patients with unilateral maxillary defect before and after maxillofacial obturator prosthesis. 15 patients with unilateral maxillary defect were included in this study, who received obturator prosthesis for maxillary rehabilitation. The pronunciation of the examined phonetics such as /a/, /o/, /e/, /i/, /u/ were transferred into CSL4400 before and after treatment. The mean value of the first, second, third formant were measured. Paired t test of SPSS11.0 was used for statistical analysis. There was statistically significant difference on F2 and F3 before and after treatment (Pvowels changed after treatment. Maxillofacial prosthesis can improve the speech function of patients with unilateral maxillary defect effectively.

  5. Topographic analysis of the maxillary premolars relative to the maxillary sinus and the alveolar bone using cone beam computed tomography.

    Science.gov (United States)

    Nishihara, Kazuhide; Yoshimine, Shin-Ichiro; Goto, Takahiro; Ishihata, Kiyohide; Kume, Ken-Ichi; Yoshimura, Takuya; Nakamura, Norifumi; Arasaki, Akira

    2017-05-01

    The purpose of the present study was to elucidate the anatomic characteristics of the maxillary premolars for the planning of dental treatment using cone beam computed tomography (CBCT). CBCT images were obtained for 150 maxillary premolars in 68 patients. The internal angle formed by the long axis of the maxillary premolars and the long axis of the alveolar bone was evaluated on the cross-sectional images. The vertical relationships between the maxillary premolars and the maxillary sinus were classified into 5 categories. The bone width and internal angle were compared among the images classified into the 5 categories. The internal angle was 25.5 ± 6.9° at the maxillary first premolars. The incidence of Type I in the maxillary first premolars was 46.7%. In the maxillary second premolars, the incidence of Type I (14.7%) was significantly lower than the total incidence of Types II, III, IV, and V (85.3%). Type I had the significantly largest internal angle (28.0 ± 7.7°) among all types for the maxillary first premolars. When considering dental treatment in the maxillary premolars, one should observe the inclination of the maxillary premolars to the alveolar bone as well as the position of the inferior wall of the maxillary sinus. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Apical surgery of a maxillary molar creating a maxillary sinus window using ultrasonics: a clinical case.

    Science.gov (United States)

    García, B; Peñarrocha, M; Peñarrocha, M A; Von Arx, T

    2010-11-01

    To describe a method of carrying out apical surgery of a maxillary molar using ultrasonics to create a lateral sinus window into the maxillary sinus and an endoscope to enhance visibility during surgery. A 37-year-old female patient presented with tenderness to percussion of the maxillary second right molar. Root canal treatment had been undertaken, and the tooth restored with a metal-ceramic crown. Radiological examination revealed an apical radiolucency in close proximity to the maxillary sinus. Apical surgery of the molar was performed through the maxillary sinus, using ultrasonics for the osteotomy, creating a window in the lateral wall of the maxillary sinus. During surgery, the lining of the sinus was exposed and elevated without perforation. The root-end was resected using a round tungsten carbide drill, and the root-end cavity was prepared with ultrasonic retrotips. Root-end filling was accomplished with MTA(®) . An endoscope was used to examine the cut root face, the prepared cavity and the root-end filling. No intraoperative or postoperative complications were observed. At the 12-month follow-up, the tooth had no clinical signs or symptoms, and the radiograph demonstrated progressing resolution of the radiolucency. When conventional root canal retreatment cannot be performed or has failed, apical surgery may be considered, even in maxillary molars with roots in close proximity to the maxillary sinus. Ultrasonic sinus window preparation allows more control and can minimize perforation of the sinus membrane when compared with conventional rotary drilling techniques. The endoscope enhances visibility during endodontic surgery, thus improving the quality of the case. © 2010 International Endodontic Journal.

  7. Neonatal maxillary orthopedics: past to present

    NARCIS (Netherlands)

    Kuijpers-Jagtman, A.M.; Prahl, C.; Berkowitz, S.

    2013-01-01

    Neonatal maxillary orthopedics was introduced in the treatment protocol for cleft lip and palate in the 1950s of the last century. A wide range of appliances has been designed with pin-retained active appliances at one end of the spectrum and passive appliances at the other. Although neonatal

  8. [Anatomy in relation to posterior maxillary osteotomy].

    Science.gov (United States)

    Hua, Z; Chen, Z; Hu, X

    2000-09-01

    The most common site of haemorrhage in maxillary osteotomies is the posterior maxilla. Better understanding of the anatomy of this region would minimize possible vascular complications. The aim of this study is to investigate the anatomy of posterior maxilla and establish safety guidelines for Le Fort I osteotomy. Thirty dry human skulls were selected for direct measurement and computerized image analysis. Synosteosis of the pterygomaxillary junction was noted in 10% of the samples. The height of the pterygomaxillary junction was 13.15 mm. The height from the inferior point of the pterygomaxillary junction to the inferior point of the maxillary tuberosity was 5.25 mm. The height from the superior point of the pterygomaxillary junction to the inferior point of the maxillary tuberrosity was 18.05 mm. The average distance from the piriform rim to the descending palatine canal was 35.25 mm. The width of the pterygoid process was 12.34 mm. The average length from the zygo-alveolar ridge to the pterygomaxillary junction was 25.47 mm. The average length from anterior nasal spine to the posterior nasal spine was 46.27 mm, and the angle between the descending palatine canal and the palate plane was 58 degrees 47'. The study is to provide further understanding of the posterior maxillary anatomy in relation to the bone-cut design of Le fort I osteotomy and to create clinical safety guidelines in order to avoid damaging the descending palatine vessels.

  9. Palatal Surface Area of Maxillary Plaster Casts

    DEFF Research Database (Denmark)

    Darvann, Tron Andre; Hermann, Nuno V.; Ersbøll, Bjarne Kjær

    2007-01-01

    -dimensional measurements of selected linear distances, curve lengths, and (surface) areas were carried out on maxillary plaster casts from individuals with unilateral or bilateral cleft lip and palate. The relationship between two-dimensional and three-dimensional measurements was investigated using linear regression...... ratio may be converted to a three-dimensional measurement by use of a multiplication factor of 0.75....

  10. Revisiting the Factors Underlying Maxillary Midline Diastema

    Directory of Open Access Journals (Sweden)

    Abdullah M. Zakria Jaija

    2016-01-01

    Full Text Available Aim. The aim of this study is to analyze the etiological factors underlying the presence of maxillary midline diastema in a sample of orthodontic patients. Materials and Methods. One hundred patients who fulfill the inclusion criteria were selected from 1355 patients seeking orthodontic treatment. The pretreatment orthodontic records were analyzed. The width of the maxillary midline diastema was measured clinically with a digital caliper at two levels: the mesioincisal angles of the central incisors and five millimeters from the incisal edge. The two measurements were averaged, and patients with diastema of more than 0.5 millimeter in width were enrolled. Results. Diastema is a multifactorial clinical finding with more than one underlying etiological cause. The interrelationship between the familial pattern of midline diastema and the microdontia, macroglossia, labial frenum, and alveolar cleft conforms was clear. The effect of a mesiodens and the upper lateral incisor whether bilaterally missing, unerupted, or peg shaped was minimal. Conclusion. Etiological factors underlying maxillary midline diastema are interconnected. Using a checklist as a guide during handling maxillary midline diastema is important in the different stages of treatment.

  11. Maxillary brown tumour: unusual presentation of parathyroid ...

    African Journals Online (AJOL)

    This is a report of a maxillary brown tumour caused by primary hyperparathyroidism (HPT) secondary to parathyroid carcinoma. A 62-year-old man presented with a large swelling in the right maxilla, which caused right-sided nasal obstruction, intermittent bleeding and diplopia. A computed tomography scan demonstrated ...

  12. Maxillary Tuberosity Reconstruction with Transport Distraction Osteogenesis

    Directory of Open Access Journals (Sweden)

    F. Ugurlu

    2012-01-01

    Full Text Available Severe bone loss due to pathology in the maxillary tuberosity region is a challenging problem both surgically and prosthetically. Large bone grafts have a poor survival rate due to the delicate bony architecture in this area and presence of the maxillary sinus. Our case presentation describes a new technique for reconstructing severe bony defect in the maxillary tuberosity with horizontal distraction osteogenesis in a 45-year-old man. A 4×6×3cm cyst was discovered in the left maxillary molar region and enucleated. Three months postoperatively, the area had a severe bone defect extending to the zygomatic buttress superiorly and hamular notch posteriorly. Three months later, a bone segment including the right upper second premolar was osteotomised and distracted horizontally. The bone segment was distracted 15 mm distally. After consolidation, implants were placed when the distractor was removed. A fixed denture was loaded over the implants after 3 months. Complete alveolar bone loss extending to the cranial base can be reconstructed with transport distraction osteogenesis. Distalisation of the alveolar bone segment adjacent to the bony defect is an easy method for reconstructing such severe defects.

  13. Rice hull/MnFe{sub 2}O{sub 4} composite: Preparation, characterization and its rapid microwave-assisted COD removal for organic wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Lv Shuangshuang [Zhejiang Institute of Geology and Mineral Resources, Hangzhou 310007 (China); Chen Xuegang [Department of Earth Sciences, Zhejiang University, Hangzhou 310027 (China); Ye Ying, E-mail: commandos2@zju.edu.cn [Department of Earth Sciences, Zhejiang University, Hangzhou 310027 (China); Yin Suhang [Department of Earth Sciences, Zhejiang University, Hangzhou 310027 (China); Cheng Jipeng [Department of Materials Science and Engineering, Zhejiang University, Hangzhou 310027 (China); Xia Meisheng [Department of Earth Sciences, Zhejiang University, Hangzhou 310027 (China)

    2009-11-15

    Adsorbent/ferrite composites can adsorb and degrade organics in the organic wastewater treatment. In this study, a rice hull/MnFe{sub 2}O{sub 4} composite (RHM) was prepared via calcination under nitrogen atmosphere and was used to treat organic wastewater with the assistance of microwave radiation. Rice hull was pyrolysed to a porous substrate that consisted of silica and activated carbon under high temperature. Monodisperse spinel MnFe{sub 2}O{sub 4} nanoparticles whose mean diameter is around 59 nm are distributed on the substrate. With the assistance of microwave radiation, RHM was motivated to a hotspot of adsorption and catalysis which could remove more than 70% COD of wastewater within 6 min. The maximum COD removal was 73.5% when the concentration of RHM was 15 mg mL{sup -1} and the irradiation time of microwave radiation was 6 min. Although the BET surface area and iodine value of RHM are half of rice hull ash (RHA), the COD removal of RHM is 7-20% higher than that of RHA. It is attributed to the presence of MnFe{sub 2}O{sub 4}, which enhances the catalytic activity of RHM. RHM can be regenerated via water washing. However, the surface area and the maximum COD removal of RHM decrease for each regeneration cycle. With the advantages of low cost and rapid processing, this novel rice hull/MnFe{sub 2}O{sub 4} composite could gain promising application in wastewater treating-agent.

  14. Radiological diagnosis of maxillary sinus aspergillosis. Radiologische Diagnostik der Kieferhoehlenaspergillose

    Energy Technology Data Exchange (ETDEWEB)

    Schulte, B.; Beyer, D. (Akademisches Lehrkrankenhaus, Porz (Germany). Radiologische Abt.)

    1992-11-01

    Aspergillosis of the maxillary sinuses shows an increasing incidence in even otherwise healthy patients. Next to inhalation as the mode of infection, a dental root canal filling with an orosinusal fistula can be the cause. As most infections remain initially undetected or underestimated as common sinusitis, early diagnosis must be achieved. Standard X-ray of the paranasal sinuses, conventional tomography as well as CT scans are of major importance. Centrally located hyperdense opacifications are a good criterion and can be best seen in CT. Even when the case has not progressed too much, radical surgery combined with Amphotericin B therapy is still the treatment of choice since the infection may progress rapidly. (orig.).

  15. Influência da expansão rápida da maxila na rizólise dos caninos decíduos usados como ancoragem Influence of rapid maxillary expansion on the root resorption of primary canines used as anchorage

    Directory of Open Access Journals (Sweden)

    Omar Gabriel da Silva Filho

    2009-10-01

    Full Text Available OBJETIVOS: o presente estudo radiográfico, retrospectivo e longitudinal objetivou determinar se a ancoragem do aparelho expansor fixo tipo Haas, modificado para as dentaduras decídua e mista, interfere na velocidade de rizólise e esfoliação dos caninos decíduos. MÉTODOS: foi feita uma avaliação quantitativa da rizólise do canino decíduo mediante a medição do comprimento coroa-ápice dos caninos decíduos superiores, dos lados direito e esquerdo. Para essa avaliação, 24 crianças submetidas à expansão rápida da maxila (ERM na dentadura decídua ou no início da dentadura mista foram comparadas com 15 crianças que não passaram por esse procedimento. A medição do comprimento coroa-ápice dos caninos decíduos foi realizada com o programa computadorizado CEF-X Cefalometria Digital, produzido pela CDT Informática, que permitiu calibrar o tamanho dos dentes pela uniformização das imagens radiográficas digitalizadas. RESULTADOS: os dados estatísticos revelaram que não houve diferença na velocidade de rizólise dos caninos decíduos entre as crianças do grupo controle e as do grupo submetido à ERM. CONCLUSÕES: é possível inferir que o aparelho expansor fixo tipo Haas ancorado em dentes decíduos não influencia a rizólise dos caninos decíduos usados como ancoragem.AIM: The current radiographic, retrospective longitudinal study aim was to demonstrate whether the Haas fixed appliance, modified for the primary and mixed dentitions, interferes in the velocity of the root resorption and exfoliation of the primary canines. METHODS: It was evaluated the amount of root resorption of primary canines on the basis of measurements of the apex-crown length of right and left upper primary canines. For this measurement twenty-four children submitted to rapid maxillary expansion (RME in the primary and mixed dentition were compared to 15 children who did not undergo such a procedure. The measurement of the apex-crown length of the

  16. Air-assisted liquid–liquid microextraction by solidifying the floating organic droplets for the rapid determination of seven fungicide residues in juice samples

    Energy Technology Data Exchange (ETDEWEB)

    You, Xiangwei [Tobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266101 (China); College of Science, China Agricultural University, Beijing 100193 (China); Xing, Zhuokan [College of Science, China Agricultural University, Beijing 100193 (China); Liu, Fengmao, E-mail: liufengmao@cau.edu.cn [College of Science, China Agricultural University, Beijing 100193 (China); Zhang, Xu [College of Science, China Agricultural University, Beijing 100193 (China)

    2015-05-22

    Highlights: • A novel AALLME-SFO method was firstly reported for pesticide residue analysis. • Solvent with low density and proper melting point was used as extraction solvent. • The formation of “cloudy solvent” with a syringe only. • The new method avoided the use of organic dispersive solvent. - Abstract: A novel air assisted liquid–liquid microextraction using the solidification of a floating organic droplet method (AALLME-SFO) was developed for the rapid and simple determination of seven fungicide residues in juice samples, using the gas chromatography with electron capture detector (GC-ECD). This method combines the advantages of AALLME and dispersive liquid–liquid microextraction based on the solidification of floating organic droplets (DLLME-SFO) for the first time. In this method, a low-density solvent with a melting point near room temperature was used as the extraction solvent, and the emulsion was rapidly formed by pulling in and pushing out the mixture of aqueous sample solution and extraction solvent for ten times repeatedly using a 10-mL glass syringe. After centrifugation, the extractant droplet could be easily collected from the top of the aqueous samples by solidifying it at a temperature lower than the melting point. Under the optimized conditions, good linearities with the correlation coefficients (γ) higher than 0.9959 were obtained and the limits of detection (LOD) varied between 0.02 and 0.25 μg L{sup −1}. The proposed method was applied to determine the target fungicides in juice samples and acceptable recoveries ranged from 72.6% to 114.0% with the relative standard deviations (RSDs) of 2.3–13.0% were achieved. Compared with the conventional DLLME method, the newly proposed method will neither require a highly toxic chlorinated solvent for extraction nor an organic dispersive solvent in the application process; hence, it is more environmentally friendly.

  17. Matrix-assisted laser desorption/ionisation-time of flight mass spectrometry: rapid identification of bacteria isolated from patients with cystic fibrosis.

    Science.gov (United States)

    Baillie, S; Ireland, K; Warwick, S; Wareham, D; Wilks, M

    2013-01-01

    Despite extensive research into the diagnosis and management of cystic fibrosis (CF) over the past decades, sufferers still have a median life expectancy of less than 37 years. Respiratory tract infections have a significant role in increasing the morbidity and mortality of patients with CF via a progressive decline in lung function. Rapid identification of organisms recovered from CF sputum is necessary for effective management of respiratory tract infections; however, standard techniques of identification are slow, technically demanding and expensive. The aim of this study is to asses the suitability of matrix-assisted laser desorption/ionisation-time of flight mass spectrometry (MALDI-TOF MS) in identifying bacteria isolated from the respiratory tract of patients with CF, and is assessed by testing the accuracy of MALDI-TOF MS in identifying samples from a reference collection of rare CF strains in conjunction with comparing MALDI-TOF MS and standard techniques in identifying clinical isolates from sputum samples of CF patients. MALDI-TOF MS accurately identified 100% of isolates from the reference collection of rare CF pathogens (EuroCare CF collection). The isolate identification given by MALDI-TOF MS agreed with that given by standard techniques for 479/481 (99.6%) clinical isolates obtained from respiratory samples provided by patients with CE In two (0.4%) of 481 samples there was a discrepancy in identification between MALDI-TOF MS and standard techniques. One organism was identified as Pseudomonas aeruginosa by MALDI-TOF but could only be identified by the laboratory's standard methods as of the Pseudomonas genus. The second organism was identified as P. beteli by MALDI-TOF MS and Stenotrophomonas maltophilia by standard methods. This study shows that MALDI-TOF MS is superior to standard techniques in providing cheap, rapid and accurate identification of CF sputum isolates.

  18. Rapid gas chromatography with flame photometric detection of multiple organophosphorus pesticides in Salvia miltiorrhizae after ultrasonication assisted one-step extraction.

    Science.gov (United States)

    Zhang, Shanshan; Liu, Xiaofei; Qin, Jia'an; Yang, Meihua; Zhao, Hongzheng; Wang, Yong; Guo, Weiying; Ma, Zhijie; Kong, Weijun

    2017-11-15

    A simple and rapid gas chromatography-flame photometric detection (GC-FPD) method was developed for the determination of 12 organophosphorus pesticides (OPPs) in Salvia miltiorrhizae by using ultrasonication assisted one-step extraction (USAE) without any clean-up steps. Some crucial parameters such as type of extraction solvent were optimized to improve the method performance for trace analysis. Any clean-up steps were negligent as no interferences were detected in the GC-FPD chromatograms for sensitive detection. Under the optimized conditions, limits of detection (LODs) and quantitation (LOQs) for all pesticides were in the range of 0.001-0.002mg/kg and 0.002-0.01mg/kg and 0.002-0.01mg/kg, respectively, which were all below the regulatory maximum residue limits suggested. RSDs for method precision (intra- and inter-day variations) were lower than 6.8% in approval with international regulations. Average recovery rates for all pesticides at three fortification levels (0.5, 1.0 and 5.0mg/kg) were in the range of 71.2-101.0% with relative standard deviations (RSDs) pesticide (dimethoate) out of the 12 targets was simultaneously detected in four samples at concentrations of 0.016-0.02mg/kg. Dichlorvos and omethoate were found in the same sample from Sichuan province at 0.004 and 0.027mg/kg, respectively. Malathion and monocrotophos were determined in the other two samples at 0.014 and 0.028mg/kg, respectively. All the positive samples were confirmed by LC-MS/MS. The simple, reliable and rapid USAE-GC-FPD method with many advantages over traditional techniques would be preferred for trace analysis of multiple pesticides in more complex matrices. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Vertical growth control during maxillary expansion using a bonded Hyrax appliance

    Directory of Open Access Journals (Sweden)

    Francisco Marcelo Paranhos Pinto

    2012-02-01

    Full Text Available INTRODUCTION: Rapid maxillary expansion (RME for the treatment of maxillary deficiency and posterior crossbite may induce changes in the vertical dimension. Expanders with occlusal splints have been developed to minimize unwanted vertical effects. OBJECTIVE: This preliminary study used cephalometri radiographs to evaluate the vertical effects of RME using a Hyrax appliance in children with maxillary deficiency. METHOD: Twenty-six patients (11 boys; mean age = 8 years and 5 months with maxillary deficiency and posterior crossbite were treated using a Hyrax appliance with an acrylic occlusal splint. Radiographs and cephalometric studies were performed before the beginning of the treatment (T1 and after RME active time (T2, at a mean interval of 7 months. Results were compared with normative values. RESULTS AND CONCLUSIONS: At the end of treatment, there were no statistically significant changes, and measurements were similar to the normative values. Data showed that there were no significant effects on vertical growth, which suggests that appliances with occlusal splints may be used to correct transverse deficiencies regardless of the patient's growth pattern.

  20. Maxillary sinus floor extension and posterior tooth inclination in adolescent patients with Class II Division 1 malocclusion treated with maxillary first molar extractions

    NARCIS (Netherlands)

    Livas, Christos; Halazonetis, Demetrios J.; Booij, Johan Willem; Pandis, Nikolaos; Tu, Yu-Kang; Katsaros, Christos

    Introduction: Our objective was to investigate potential associations between maxillary sinus floor extension and inclination of maxillary second premolars and second molars in patients with Class II Division 1 malocclusion whose orthodontic treatment included maxillary first molar extractions.

  1. Maxillary sinus floor extension and posterior tooth inclination in adolescent patients with Class II Division 1 malocclusion treated with maxillary first molar extractions

    NARCIS (Netherlands)

    Livas, C.; Halazonetis, D.J.; Booij, J.W.; Pandis, N.; Tu, Y.K.; Katsaros, C.

    2013-01-01

    INTRODUCTION: Our objective was to investigate potential associations between maxillary sinus floor extension and inclination of maxillary second premolars and second molars in patients with Class II Division 1 malocclusion whose orthodontic treatment included maxillary first molar extractions.

  2. Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption/Ionisation mass spectrometric typing

    Science.gov (United States)

    2012-01-01

    Background Burkholderia (B.) pseudomallei and B. mallei are genetically closely related species. B. pseudomallei causes melioidosis in humans and animals, whereas B. mallei is the causative agent of glanders in equines and rarely also in humans. Both agents have been classified by the CDC as priority category B biological agents. Rapid identification is crucial, because both agents are intrinsically resistant to many antibiotics. Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-TOF MS) has the potential of rapid and reliable identification of pathogens, but is limited by the availability of a database containing validated reference spectra. The aim of this study was to evaluate the use of MALDI-TOF MS for the rapid and reliable identification and differentiation of B. pseudomallei and B. mallei and to build up a reliable reference database for both organisms. Results A collection of ten B. pseudomallei and seventeen B. mallei strains was used to generate a library of reference spectra. Samples of both species could be identified by MALDI-TOF MS, if a dedicated subset of the reference spectra library was used. In comparison with samples representing B. mallei, higher genetic diversity among B. pseudomallei was reflected in the higher average Eucledian distances between the mass spectra and a broader range of identification score values obtained with commercial software for the identification of microorganisms. The type strain of B. pseudomallei (ATCC 23343) was isolated decades ago and is outstanding in the spectrum-based dendrograms probably due to massive methylations as indicated by two intensive series of mass increments of 14 Da specifically and reproducibly found in the spectra of this strain. Conclusions Handling of pathogens under BSL 3 conditions is dangerous and cumbersome but can be minimized by inactivation of bacteria with ethanol, subsequent protein extraction under BSL 1 conditions and MALDI-TOF MS analysis being faster than

  3. Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption/Ionisation mass spectrometric typing.

    Science.gov (United States)

    Karger, Axel; Stock, Rüdiger; Ziller, Mario; Elschner, Mandy C; Bettin, Barbara; Melzer, Falk; Maier, Thomas; Kostrzewa, Markus; Scholz, Holger C; Neubauer, Heinrich; Tomaso, Herbert

    2012-10-10

    Burkholderia (B.) pseudomallei and B. mallei are genetically closely related species. B. pseudomallei causes melioidosis in humans and animals, whereas B. mallei is the causative agent of glanders in equines and rarely also in humans. Both agents have been classified by the CDC as priority category B biological agents. Rapid identification is crucial, because both agents are intrinsically resistant to many antibiotics. Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-TOF MS) has the potential of rapid and reliable identification of pathogens, but is limited by the availability of a database containing validated reference spectra. The aim of this study was to evaluate the use of MALDI-TOF MS for the rapid and reliable identification and differentiation of B. pseudomallei and B. mallei and to build up a reliable reference database for both organisms. A collection of ten B. pseudomallei and seventeen B. mallei strains was used to generate a library of reference spectra. Samples of both species could be identified by MALDI-TOF MS, if a dedicated subset of the reference spectra library was used. In comparison with samples representing B. mallei, higher genetic diversity among B. pseudomallei was reflected in the higher average Eucledian distances between the mass spectra and a broader range of identification score values obtained with commercial software for the identification of microorganisms. The type strain of B. pseudomallei (ATCC 23343) was isolated decades ago and is outstanding in the spectrum-based dendrograms probably due to massive methylations as indicated by two intensive series of mass increments of 14 Da specifically and reproducibly found in the spectra of this strain. Handling of pathogens under BSL 3 conditions is dangerous and cumbersome but can be minimized by inactivation of bacteria with ethanol, subsequent protein extraction under BSL 1 conditions and MALDI-TOF MS analysis being faster than nucleic amplification methods. Our

  4. Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption/Ionisation mass spectrometric typing

    Directory of Open Access Journals (Sweden)

    Karger Axel

    2012-10-01

    Full Text Available Abstract Background Burkholderia (B. pseudomallei and B. mallei are genetically closely related species. B. pseudomallei causes melioidosis in humans and animals, whereas B. mallei is the causative agent of glanders in equines and rarely also in humans. Both agents have been classified by the CDC as priority category B biological agents. Rapid identification is crucial, because both agents are intrinsically resistant to many antibiotics. Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-TOF MS has the potential of rapid and reliable identification of pathogens, but is limited by the availability of a database containing validated reference spectra. The aim of this study was to evaluate the use of MALDI-TOF MS for the rapid and reliable identification and differentiation of B. pseudomallei and B. mallei and to build up a reliable reference database for both organisms. Results A collection of ten B. pseudomallei and seventeen B. mallei strains was used to generate a library of reference spectra. Samples of both species could be identified by MALDI-TOF MS, if a dedicated subset of the reference spectra library was used. In comparison with samples representing B. mallei, higher genetic diversity among B. pseudomallei was reflected in the higher average Eucledian distances between the mass spectra and a broader range of identification score values obtained with commercial software for the identification of microorganisms. The type strain of B. pseudomallei (ATCC 23343 was isolated decades ago and is outstanding in the spectrum-based dendrograms probably due to massive methylations as indicated by two intensive series of mass increments of 14 Da specifically and reproducibly found in the spectra of this strain. Conclusions Handling of pathogens under BSL 3 conditions is dangerous and cumbersome but can be minimized by inactivation of bacteria with ethanol, subsequent protein extraction under BSL 1 conditions and MALDI-TOF MS

  5. Principle component analysis combined with matrix-assisted laser desorption ionization mass spectrometry for rapid diagnosing the sera of patients with major depression.

    Science.gov (United States)

    Huang, Tiao-Lai; Cho, Yi-Tzu; Su, Hong; Shiea, Jentaie

    2013-09-23

    Previously, we demonstrated that 6M HCl hydrolysis followed by matrix-assisted laser desorption/ionization (MALDI-TOF) mass spectrometry is a useful technique to detect potential protein biomarkers in the sera collected from major depression (MD) patients and from healthy controls. In this study, the effects of various organic acids in hydrolyzing proteins in serum were first examined. The organic matrixes commonly used in MALDI analysis were also examined for characterizing the hydrolyzed peptides. Finally, principle component analysis (PCA) was used to analyze the MALDI mass spectra of acid-hydrolyzed serum samples. It was found that 20% TFA and sinapinic acid were the optimal reagents for hydrolysis and MALDI matrix. Samples collected from MD patients and healthy controls were readily classified through PCA analysis. A receiver operating characteristic (ROC) curve based on the ratio of the intensities of the two fragment ions (m/z 8606 and 9287) indicated by PCA plot was also constructed. The area under the curve was 0.845; the sensitivity and specificity were both 80%. An analytical platform employing trifluoroacetic acid to hydrolyze serum proteins followed by MALDI-TOF/MS and PCA analysis was developed to rapidly differentiate the sera between MD patients and healthy controls. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry rapid detection of carbapenamase activity in Acinetobacter baumannii isolates.

    Science.gov (United States)

    Abouseada, Noha; Raouf, May; El-Attar, Eman; Moez, Pacinte

    2017-01-01

    Carbapenamase-producing Acinetobacter baumannii are an increasing threat in hospitals and Intensive Care Units. Accurate and rapid detection of carbapenamase producers has a great impact on patient improvement and aids in implementation of infection control measures. In this study, we describe the use of matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI TOF MS) to identify carbapenamase-producing A. baumannii isolates in up to 3 h. Isolates and Methods: A total of 50 A. baumannii isolates (of which 39 were carabapenamase producers) were tested using MALDI TOF MS. Isolates were incubated for 3 h with 0.25 mg/ml up to 2 mg/ml of imipenem (IMP) at 37°C. Supernatants were analysed by MALDI TOF to analyse peaks corresponding to IMP (300 Da) and an IMP metabolite (254 Da) using UltrafleXtreme (Bruker Daltonics, Bremen, Germany). All carbapenamase-producing isolates were evidenced by the disappearance or reduction in intensity of the 300 Da peak of IPM and the appearance of a 254 Da peak of the IPM metabolite. In isolates that did not produce carbapenamase, the IPM 300 Da peak remained intact. MALDI TOF is a promising tool in the field of diagnostic microbiology that has the ability to transfer identification and antimicrobial susceptibility testing time from days to hours.

  7. Rapid determination of 54 pharmaceutical and personal care products in fish samples using microwave-assisted extraction-Hollow fiber-Liquid/solid phase microextraction.

    Science.gov (United States)

    Zhang, Yi; Guo, Wen; Yue, Zhenfeng; Lin, Li; Zhao, Fengjuan; Chen, Peijin; Wu, Weidong; Zhu, Hong; Yang, Bo; Kuang, Yanyun; Wang, Jiong

    2017-04-15

    In this paper, a simple, rapid, solvent-less and environmental friendliness microextraction method, microwave-assisted extraction-hollow fiber-liquid/solid phase microextraction (MAE-HF-L/SME), was developed for simultaneous extraction and enrichment of 54 trace hydrophilic/lipophilic pharmaceutical and personal care products (PPCPs) from fish samples. A solid-phase extraction material, solid-phase microextraction (SPME) fiber, was synthesized. The SPME fiber had a homogeneous, loose structure and good mechanical properties, and they exhibited a good adsorption capacity for most PPCPs selected. The material formed the basis for the method of MAE-HF-L/SME. A method of liquid chromatography-high resolution mass spectroscopy (LC-HRMS) for analysis of 54 PPCPs. Under optimal synthesis and extraction conditions, the limits of detection (LODs, n=3) and the limits of quantitation (LOQs, n=10) for the 54 PPCPs were between 0.01-0.50μg·kg-1 and 0.052.00μg·kg-1, respectively. Percent recoveries and the relative standard deviations (RSDs) in spiked fish samples (n=6) were between 56.3%-119.9% and 0.3%-17.1%, respectively. The microextraction process of 54 PPCPs in MAE-HF-L/SME took approximately 12min. The method has a low matrix interference and high enrichment factor and may be applicable for determination of 54 different PPCPs in fish samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Oil palm trunk and sugarcane bagasse derived solid acid catalysts for rapid esterification of fatty acids and moisture-assisted transesterification of oils under pseudo-infinite methanol.

    Science.gov (United States)

    Ezebor, Francis; Khairuddean, Melati; Abdullah, Ahmad Zuhairi; Boey, Peng Lim

    2014-04-01

    The use of pseudo-infinite methanol in increasing the rate of esterification and transesterification reactions was studied using oil palm trunk (OPT) and sugarcane bagasse (SCB) derived solid acid catalysts. The catalysts were prepared by incomplete carbonisation at 400°C for 8h, followed by sulfonation at 150°C for 15h and characterised using TGA/DTA, XRD, FT-IR, SEM-EDS, EA and titrimetric determinations of acid sites. Under optimal reaction conditions, the process demonstrated rapid esterification of palmitic acid, with FAME yields of 93% and 94% in 45min for OPT and SCB catalysts, respectively. With the process, moisture levels up to 16.7% accelerated the conversion of low FFA oils by sulfonated carbon catalysts, through moisture-induced violent bumping. Moisture assisted transesterification of palm olein containing 1.78% FFA and 8.33% added water gave FAME yield of 90% in 10h, which was two folds over neat oil. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Sensitive, accurate and rapid detection of trace aliphatic amines in environmental samples with ultrasonic-assisted derivatization microextraction using a new fluorescent reagent for high performance liquid chromatography.

    Science.gov (United States)

    Chen, Guang; Liu, Jianjun; Liu, Mengge; Li, Guoliang; Sun, Zhiwei; Zhang, Shijuan; Song, Cuihua; Wang, Hua; Suo, Yourui; You, Jinmao

    2014-07-25

    A new fluorescent reagent, 1-(1H-imidazol-1-yl)-2-(2-phenyl-1H-phenanthro[9,10-d]imidazol-1-yl)ethanone (IPPIE), is synthesized, and a simple pretreatment based on ultrasonic-assisted derivatization microextraction (UDME) with IPPIE is proposed for the selective derivatization of 12 aliphatic amines (C1: methylamine-C12: dodecylamine) in complex matrix samples (irrigation water, river water, waste water, cultivated soil, riverbank soil and riverbed soil). Under the optimal experimental conditions (solvent: ACN-HCl, catalyst: none, molar ratio: 4.3, time: 8 min and temperature: 80°C), micro amount of sample (40 μL; 5mg) can be pretreated in only 10 min, with no preconcentration, evaporation or other additional manual operations required. The interfering substances (aromatic amines, aliphatic alcohols and phenols) get the derivatization yields of impurities. With this UDME-HPLC-FD-MS method, the accuracy (-0.73-2.12%), precision (intra-day: 0.87-3.39%; inter-day: 0.16-4.12%), recovery (97.01-104.10%) and sensitivity were significantly improved. Successful applications in environmental samples demonstrate the superiority of this method in the sensitive, accurate and rapid determination of trace aliphatic amines in micro amount of complex samples. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. A Facile and Microwave-assisted Rapid Synthesis of 2-Arylamino-4-(3'-indolyl)- thiazoles as Apoptosis Inducing Cytotoxic Agents.

    Science.gov (United States)

    Tantak, Mukund P; Mukherjee, Dipanwita Das; Kumar, Anil; Chakrabarti, Gopal; Kumar, Dalip

    2017-01-01

    The clinical success of the chemotherapeutic drugs is restricted by the nonspecific toxicity-related adverse side effects. The diverse implication of indoles and thiazoles in medicinal chemistry prompted us to develop a new series of novel 2-aryl-amino-4-(3'-indolyl)thiazoles as more effective and less toxic anti-cancer compounds. One-pot microwave-assisted rapid and high yielding synthesis of 2-arylamino-4-(3'- indolyl)thiazoles involved the reaction of easily available α-tosyloxy-ketones with N-arylthioureas in polyethylene glycol-400 (PEG-400). In vitro cytotoxicity study of 2-arylamino-4-(3'-indolyl)thiazoles against a panel of human cancer cell lines by MTT assay revealed IC50 values in the low micromolar range. Of the fifteen synthesized arylaminothiazoles, compounds 17b, 17d, 17g and 17il showed significant anti-proliferative activity against the selected cancer cell lines with IC50 synthesis for 2-arylamino-4-(3'-indolyl)thiazoles, and their in vitro cytotoxicity studies demonstrate that compound 17b exhibits significant anti-proliferative activity against MCF-7 (breast cancer) cells by activating ROS-mediated apoptosis through the mitochondrial apoptosis pathway. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  11. Following Surgically Assisted Rapid Palatal Expansion, Do Tooth-Borne or Bone-Borne Appliances Provide More Skeletal Expansion and Dental Expansion?

    Science.gov (United States)

    Hamedi-Sangsari, Adrien; Chinipardaz, Zahra; Carrasco, Lee

    2017-10-01

    The aim of this study was to compare outcome measurements of skeletal and dental expansion with bone-borne (BB) versus tooth-borne (TB) appliances after surgically assisted rapid palatal expansion (SARPE). This study was performed to provide quantitative measurements that will help the oral surgeon and orthodontist in selecting the appliance with, on average, the greatest amount of skeletal expansion and the least amount of dental expansion. A computerized database search was performed using PubMed, EBSCO, Cochrane, Scopus, Web of Science, and Google Scholar on publications in reputable oral surgery and orthodontic journals. A systematic review and meta-analysis was completed with the predictor variable of expansion appliance (TB vs BB) and outcome measurement of expansion (in millimeters). Of 487 articles retrieved from the 6 databases, 5 articles were included, 4 with cone-beam computed tomographic (CBCT) data and 1 with non-CBCT 3-dimensional cast data. There was a significant difference in skeletal expansion (standardized mean difference [SMD], 0.92; 95% confidence interval [CI], 0.54-1.30; P < .001) in favor of BB rather than TB appliances. However, there was no significant difference in dental expansion (SMD, 0.05; 95% CI, -0.24 to 0.34; P = .03). According to the literature, to achieve more effective skeletal expansion and minimize dental expansion after SARPE, a BB appliance should be favored. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  12. Optimization of alcohol-assisted dispersive liquid-liquid microextraction by experimental design for the rapid determination of fluoxetine in biological samples.

    Science.gov (United States)

    Hamedi, Raheleh; Hadjmohammadi, Mohammad Reza

    2016-12-01

    A sensitive and rapid method based on alcohol-assisted dispersive liquid-liquid microextraction followed by high-performance liquid chromatography for the determination of fluoxetine in human plasma and urine samples was developed. The effects of six parameters on the extraction recovery were investigated and optimized utilizing Plackett-Burman design and Box-Benken design, respectively. According to the Plackett-Burman design results, the volume of disperser solvent, extraction time, and stirring speed had no effect on the recovery of fluoxetine. The optimized conditions included a mixture of 172 μL of 1-octanol as extraction solvent and 400 μL of methanol as disperser solvent, pH of 11.3 and 0% w/v of salt in the sample solution. Replicating the experiment in optimized condition for five times, gave the average extraction recoveries equal to 90.15%. The detection limit of fluoxetine in human plasma was obtained 3 ng/mL, and the linearity was in the range of 10-1200 ng/mL. The corresponding values for human urine were 4.2 ng/mL with the linearity range from 10 to 2000 ng/mL. Relative standard deviations for intra and inter day extraction of fluoxetine were less than 7% in five measurements. The developed method was successfully applied for the determination of fluoxetine in human plasma and urine samples. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Development and validation of an HPLC method for the determination of alk(en)ylresorcinols using rapid ultrasound-assisted extraction of mango peels and rye grains.

    Science.gov (United States)

    Geerkens, Christian H; Matejka, Anna E; Carle, Reinhold; Schweiggert, Ralf M

    2015-02-15

    Exhaustive extraction of alk(en)ylresorcinols (ARs) from biological matrices is a prerequisite for economic screening of extensive plant collections including their rapid quantitation. For this purpose, an ultrasound-assisted extraction protocol was developed to facilitate the liberation of ARs from mango peels (Mangifera indica L.) and rye grains (Secale cereale L.). While maintaining or even improving the extraction efficiency of the analytes, the duration of analytical extraction was shortened from more than 1h to only 45s as compared to previous methods. In addition, sample weight and solvent use were significantly reduced. Besides the validation of the extraction procedure, validation parameters for the HPLC-DAD-MS(n) based characterisation and quantitation method are provided. In particular, fully satisfactory recovery rates and quantitation limits were achieved, and coefficients of variation (CV) for repeatability and reproducibility were ⩽8 and mango and three rye cultivars, and the results were compared to previously published data. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Mass fingerprint analysis of spider mites (Acari) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for rapid discrimination.

    Science.gov (United States)

    Kajiwara, Hideyuki; Hinomoto, Norihide; Gotoh, Tetsuo

    2016-04-30

    Discrimination of spider mite species is still performed using morphological information, although DNA and other biological approaches have been attempted for identification purposes. These techniques need much time, are expensive, and require specialist staff. As an alternative, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) analysis is applied for rapid discrimination of spider mite species. Spider mites were analyzed using MALDI-TOFMS after extraction with 70% formic acid and acetonitrile. A single spider mite was also analyzed directly on double-sided carbon tape. A dendrogram was compiled from the MS data. Evolutionarily close and morphologically similar spider mites, the Kanzawa (Tetranychus kanzawai) and the two-spotted (T. urticae) spider mites, as well as three other related species of spider mites, could be discriminated by mass fingerprints. Although female adults were mainly used in this report, male adults and nymphs showed almost the same mass fingerprints and were not considered to affect discrimination capability. A single spider mite on double-sided carbon tape was analyzed directly by MALDI-TOFMS. Spider mites could be analyzed directly by MALDI-TOFMS, with evolutionarily and morphologically closely related spider mites showing different mass fingerprints, allowing for their identification. Copyright © 2016 John Wiley & Sons, Ltd.

  15. Rapid analysis of Fructus forsythiae essential oil by ionic liquids-assisted microwave distillation coupled with headspace single-drop microextraction followed by gas chromatography-mass spectrometry.

    Science.gov (United States)

    Jiao, Jiao; Ma, Dan-Hui; Gai, Qing-Yan; Wang, Wei; Luo, Meng; Fu, Yu-Jie; Ma, Wei

    2013-12-04

    A rapid, green and effective miniaturized sample preparation and analytical technique, i.e. ionic liquids-assisted microwave distillation coupled with headspace single-drop microextraction (ILAMD-HS-SDME) followed by gas chromatography-mass spectrometry (GC-MS) was developed for the analysis of essential oil (EO) in Fructus forsythiae. In this work, ionic liquids (ILs) were not only used as the absorption medium of microwave irradiation but also as the destruction agent of plant cell walls. 1-Ethyl-3-methylimidazolium acetate ([C2mim]OAc) was chosen as the optimal ILs. Moreover, n-heptadecane (2.0 μL) was selected as the appropriate suspended solvent for the extraction and concentration of EO. Extraction conditions of the proposed method were optimized using the relative peak area of EO constituents as the index, and the optimal operational parameters were obtained as follows: irradiation power (300 W), sample mass (0.7 g), mass ratio of ILs to sample (2.4), temperature (78°C) and time (3.4 min). In comparison to previous reports, the proposed method was faster and required smaller sample amount but could equally monitor all EO constituents with no significant differences. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Anatomic (positional) variation of maxillary wisdom teeth with special regard to the maxillary sinus.

    Science.gov (United States)

    Lanzer, Martin; Pejicic, Rada; Kruse, Astrid L; Schneider, Thomas; Grätz, Klaus W; Lübbers, Heinz-Theo

    2015-01-01

    The removal of wisdom teeth is one of the most common interventions in oral surgery. In order to avoid complications, a profound knowledge of the anatomy of teeth and adjacent tissues is crucial. In the case of maxillary wisdom teeth, their relationship to the maxillary sinus, to the pterygoid fossa, to the maxillary tuber and the adjacent venous plexus is particularly important. Three-dimensional (3D) imaging, for example by means of cone beam computed tomography (CBCT), is increasingly utilized in practice. However, the necessity of CBCT imaging is still a matter of intensive debate. The aim of this study was to describe the anatomic (positional) variation of maxillary wisdom teeth and, based on these findings, to elucidate the additional benefit of such imaging. A retrospective case study was performed using patients examined by means of CBCT imaging in the Department of Dento-Maxillofacial Radiology during the period from 2008 to 2013. Primary study variables comprised the spatial relationship of the teeth to the maxillary sinus, the degree of retention and root development, the covering of the root with bone and mucosa, the root configuration, and the developmental stage of the tooth. In addition, the association of the inclination of teeth in the transversal and sagittal plane with the above variables was evaluated. Descriptive statistical parameters were calculated for all results of the examination. In total, CBCT recordings of 713 maxillary wisdom teeth from 430 patients were evaluated. Their mean age was 29.8 years, and the proportion of male patients slightly prevailed (54.4%). Most teeth exhibited fully developed roots (64.1%). Overall 22.9% of third molars were impacted, 32.3% were retained, and 6.5% were erupting. In more than a third of the patients, wisdom teeth were in occlusion. The inclination of the third molars both in the transversal and sagittal plane was significantly associated with the distance of the root from the maxillary sinus as well

  17. Infantile maxillary sinus osteomyelitis mimicking orbital cellulitis

    Directory of Open Access Journals (Sweden)

    Nagarajan Krishnan

    2014-01-01

    Full Text Available Periorbital soft tissue swelling may result due to primary orbital pathology or from adjacent facio-maxillary or sino-nasal inflammatory causes. Osteomyelitis of maxilla in the pediatric age group is a rare entity in this era of antibiotics. We present an 11-month-old female infant who was brought with peri-orbital selling and purulent nasal discharge. Computed Tomography showed erosions of the walls of maxillary sinus suggestive of osteomyelitis. Culture of sinus scraping showed Staphylococcus aureus growth and the child improved with intravenous cloxacillin therapy. This case is presented due to the rarity of its presentation in this age group and for awareness to consider this entity in children having fever and peri-orbital swelling.

  18. Radiology in diagnostics of odontogenic maxillary sinusitis

    Directory of Open Access Journals (Sweden)

    Chekhonatskaya М.L

    2013-09-01

    Full Text Available The purpose: to prove diagnostic capabilities of modern radiation techniques in odontogenic maxillary sinusitis. Material and methods: The study involved 546 patients with sinusitis. The following methods have been used: X-ray of the paranasal sinuses, contrast maxillary sinus radiography, contact intraoral radiographs, orthopantomography, computer tomography and magnetic resonance imaging. Results. In 7,9% of cases the presence of odontogenic sinusitis has been established, in 92,1 % rhinogenous sinusitis has been revealed. The work provides information about the effectiveness of various radiation techniques in the diagnosis of odontogenic sinusitis. Conclusion. For suspected odontogenic sinusitis, treatment of choice includes the combined use of X-ray of the paranasal sinuses in the mentoanterior projection and contact intraoral radiographs of «causal teeth». Computer tomography is the most informative additional method to clarify the diagnosis of odontogenic sinusitis.

  19. Maxillary sinusitis as a complication of infected dens invaginatus in maxillary lateral incisor: A case report

    Directory of Open Access Journals (Sweden)

    Paras Mull Gehlot

    2015-01-01

    Full Text Available Introduction: Maxillary sinusitis can have various origins, including odontogenic origin. Case Report: We describe a case of maxillary sinusitis in a 25-year-old female patient who experienced pain and swelling in the right maxillary region as a complication of infected maxillary lateral incisor. Clinical and radiographic examinations revealed dens invaginatus (DI; Oehler′s type III associated with apical pathosis in the maxillary right lateral incisor, with a large periapical lesion involving the adjacent four teeth. Nonsurgical root canal treatment using calcium hydroxide medicament was carried out for all five teeth, which resulted in gradual diminution of sinusitis, and the patient remained asymptomatic. Discussion: This paper emphasizes the following: (i the challenges posed by DI for root canal treatment because of its anatomical complexity; (ii a nonsurgical approach in the management of a large periapical lesion, using calcium hydroxide medicament; and (iii the interdisciplinary management of conditions of common clinical concern for medical and dental practitioners, for successful outcome.

  20. A cone-beam computed tomography evaluation of buccal bone thickness following maxillary expansion

    Energy Technology Data Exchange (ETDEWEB)

    Akyalcin, Sercan; Englih, Jeryl D.; Stephens, Claude R.; Winkelmann, Sam [Dept. of Orthodontics, School of Dentistry, University of Texas Health Science Center at Houston, Houston (United States); Schaefer, Jeffrey S. [Todd Hughes Orthodontics, Houston (United States)

    2013-06-15

    This study was performed to determine the buccal alveolar bone thickness following rapid maxillary expansion (RME) using cone-beam computed tomography (CBCT). Twenty-four individuals (15 females, 9 males; 13.9 years) that underwent RME therapy were included. Each patient had CBCT images available before (T1), after (T2), and 2 to 3 years after (T3) maxillary expansion therapy. Coronal multiplanar reconstruction images were used to measure the linear transverse dimensions, inclinations of teeth, and thickness of the buccal alveolar bone. One-way ANOVA analysis was used to compare the changes between the three times of imaging. Pairwise comparisons were made with the Bonferroni method. The level of significance was established at p<0.05. The mean changes between the points in time yielded significant differences for both molar and premolar transverse measurements between T1 and T2 (p<0.05) and between T1 and T3 (p<0.05). When evaluating the effect of maxillary expansion on the amount of buccal alveolar bone, a decrease between T1 and T2 and an increase between T2 and T3 were found in the buccal bone thickness of both the maxillary first premolars and maxillary first molars. However, these changes were not significant. Similar changes were observed for the angular measurements. RME resulted in non-significant reduction of buccal bone between T1 and T2. These changes were reversible in the long-term with no evident deleterious effects on the alveolar buccal bone.

  1. Management of an extremely displaced maxillary canine.

    Science.gov (United States)

    Grande, Torsten; Stolze, Annemarie; Goldbecher, Heiko

    2005-07-01

    Aligning a displaced maxillary canine into the dental arch is one of the most complicated problems in orthodontics. In cases of extremely high displacement, the tooth is frequently removed surgically. Because of the upper canines' significance to dental esthetics and functional occlusion, such a decision is a very serious one. This case report illustrates the treatment of an extremely high displaced maxillary canine. The main diagnosis was the displacement and the retention of tooth 13 (in nearly horizontal position, apical to the neighboring teeth); further diagnoses were: transversal maxillary deficiency with frontal crowding and a distal bite of one premolar in width, a deep bite of 6 mm with contact in the palatal mucosa, mandibular midline deviation of 2.5 mm to the right, lingual eruption of teeth 32 and 42, retroinclination of the maxillary incisors, and retarded eruption of the permanent teeth. Initial treatment with active and functional appliances to correct the distal bite, midline deviation and deep bite. Surgical exposure of the high displaced canine at the age of 14. Onset of cuspid elongation with removable appliances and elastics, further movement with a transpalatinal bar and welded arm, and full alignment of the upper and lower arches with fixed appliances in both jaws. Stabilization of the orthodontic treatment results with retention devices. Duration of treatment: 5 years and 8 months. For the alignment of tooth 13, 2 years and 10 months were required; 1 year and 4 months were necessary with complete fixed appliance. The aim of this case report was to demonstrate the potential of aligning an extremely displaced canine. Because of the esthetic and functional importance of the upper canines, therapeutic alignment should be initiated, provided there are no indications to the contrary.

  2. Transcultural perception of maxillary midline diastema.

    Science.gov (United States)

    Akinboboye, Bolanle; Umesi, Donna; Ajayi, Yetunde

    2015-01-01

    Perception of maxillary midline diastema as an esthetic trait varies in relation to culture, age group, and racial background. Although midline diastema is accepted in Africa, there are few reports on interethnic perception of midline diastema among Nigerians. Participants aged 19 to 45 years were selected from six geographical zones of Nigeria; one state was randomly selected from each zone, and a local government area (LGA) selected from each state. A structured questionnaire including a set of color smile photographs with varying sizes of maxillary midline diastema (narrowest=2 mm; widest=6 mm) was administered. Information sought was age, gender, socioeconomic group, tribe, presence of a midline diastema, and grading of attractiveness of smile. This information was evaluated using a Likert scale. A total of 402 subjects aged 19 to 45 years and a mean age of 36.3 years (±0.714) took part in this study. The highest proportion of subjects with midline diastema was aged 21 to 30 years (33.9%), females (29.8%), from the Hausa ethnic group (35%), and from the class II socioeconomic group (31.9%). Among the ethnic groups, Hausa had the highest (65%) preference for midline diastema. Females (58.8%) and those in the class II socioeconomic group (68.1%) also had the highest preference for midline diastema. There was a strong relationship between incidence of and preference for midline diastema (P=0.000). All ethnic groups rated maxillary midline diastema as attractive, especially when the width was within 2 to 3 mm (P=0.02). All ethnic groups perceived maxillary midline diastema to be an esthetic attribute, provided the width was within 2 to 3 mm.

  3. Craniofacial repercussions in maxillary lateral incisors agenesis.

    Science.gov (United States)

    Pinho, Teresa; Pollmann, Cristina; Calheiros-Lobo, Maria João; Sousa, Alda; Lemos, Carolina

    2011-09-01

    Assessment of the influence of maxillary lateral incisor agenesis (MLIA) on the facial morphogenesis. Evaluation of the skeletal dimensions of the upper maxilla and its incisor region. Analysis was performed among three groups: individuals with MLIA, its relatives and the normal population. Among these a comparison between adults and growing individuals was performed. MLIA may interfere with the maxillary length and the anterosuperior facial height, negatively conditioning on its potential growth. MLIA was not correlated with changes of the palatine plane inclination, maxillary height nor with adjustment of the anterior nasal spine dimensions related to the Frankfurt plan or to the posterior nasal spine-Frankfurt plan during the observed development stage; the backward angle of the incisors in children with bilateral agenesis of lateral incisors appear to have been corrected in adulthood. MLIA is associated with an upper maxilla shortening, and appear to interfere significantly with the anterior facial height, reducing its potential size. Copyright © 2011 CEO. Published by Elsevier Masson SAS. All rights reserved.

  4. Microarchitectural pattern of pristine maxillary bone.

    Science.gov (United States)

    Monje, Alberto; González-García, Raúl; Monje, Florencio; Chan, Hsun-Liang; Galindo-Moreno, Pablo; Suarez, Fernando; Wang, Hom-Lay

    2015-01-01

    There is limited evidence available on the influence of location on bone density in the maxilla. Therefore, this study was aimed at comparing the microarchitecture of bone harvested from different nonatrophic maxillary locations. A total of 37 partially edentulous subjects (aged 48.15 ± 15.85 years) were included in the study. A bone core biopsy specimen was obtained from one site per patient at the planned implant surgery location. Thirty-four specimens were used for microcomputed tomography (micro-CT) analysis. Mann-Whitney U tests (independent samples) were performed to determine whether the distributions of the six bone-related parameters showed significant differences between sexes and site locations. Study sites were categorized as either anterior (incisors and canines) or posterior (premolars and molars). The possible associations among variables (bone volume fraction [BV/TV], age, and five bone-related parameters) were examined using the Spearman rank correlation test. The mean BV/TV values showed no significant difference between the maxillary anterior (46.93 ± 26.2) and posterior (51.90 ± 28.42) locations. Statistically significant positive correlations were identified between BV/TV and trabecular thickness (Tb.Th) (r = 0.6, P Bone density was independent of the anatomical location, assessed by micro-CT in the pristine nonatrophic maxillary bone. Studies with a larger sample size and different population should be conducted to validate the findings of the current project.

  5. Internal Maxillary Bypass for Complex Pediatric Aneurysms.

    Science.gov (United States)

    Wang, Long; Lu, Shuaibin; Qian, Hai; Shi, Xiang'en

    2017-07-01

    Complex pediatric aneurysms (PAs) are an unusual clinicopathologic entity. Data regarding the use of a bypass procedure to treat complex PAs are limited. Internal maxillary artery-to-middle cerebral artery bypass with radial artery graft was used to isolate PAs. Bypass patency and aneurysm stability were evaluated using intraoperative Doppler ultrasound, indocyanine green videoangiography, and postoperative angiography. Modified Rankin Scale was used to assess neurologic function. Over a 5-year period, 7 pediatric patients (≤18 years old) were included in our analysis. Mean age of patients was 14.4 years (range, 12-18 years), and mean size of PAs was 23.6 mm (range, 9-37 mm). All cases manifested with complex characteristics. Proximal artery occlusion was performed in 3 cases, complete excision following aneurysmal distal internal maxillary artery bypass was performed in 2 cases, and combined proximal artery occlusion and aneurysm excision was performed in the 2 remaining cases. Mean intraoperative blood flow was 61.6 mL/minute (range, 40.0-90.8 mL/minute). Graft patency rate was 100% during postoperative recovery and at the last follow-up examination (mean, 20 months; range, 7-45 months). All patients had excellent outcomes except for 1 patient who died of multiple-organ failure. Internal maxillary artery bypass is an essential technique for treatment of selected cases of complex PAs. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Rapid and reliable species identification of wild mushrooms by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS).

    Science.gov (United States)

    Sugawara, Ryota; Yamada, Sayumi; Tu, Zhihao; Sugawara, Akiko; Suzuki, Kousuke; Hoshiba, Toshihiro; Eisaka, Sadao; Yamaguchi, Akihiro

    2016-08-31

    Mushrooms are a favourite natural food in many countries. However, some wild species cause food poisoning, sometimes lethal, due to misidentification caused by confusing fruiting bodies similar to those of edible species. The morphological inspection of mycelia, spores and fruiting bodies have been traditionally used for the identification of mushrooms. More recently, DNA sequencing analysis has been successfully applied to mushrooms and to many other species. This study focuses on a simpler and more rapid methodology for the identification of wild mushrooms via protein profiling based on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF MS). A preliminary study using 6 commercially available cultivated mushrooms suggested that a more reproducible spectrum was obtained from a portion of the cap than from the stem of a fruiting body by the extraction of proteins with a formic acid-acetonitrile mixture (1 + 1). We used 157 wild mushroom-fruiting bodies collected in the centre of Hokkaido from June to November 2014. Sequencing analysis of a portion of the ribosomal RNA gene provided 134 identifications of mushrooms by genus or species, however 23 samples containing 10 unknown species that had lower concordance rate of the nucleotide sequences in a BLAST search (less than 97%) and 13 samples that had unidentifiable poor or mixed sequencing signals remained unknown. MALDI-TOF MS analysis yielded a reproducible spectrum (frequency of matching score ≥ 2.0 was ≥6 spectra from 12 spectra measurements) for 114 of 157 samples. Profiling scores that matched each other within the database gave correct species identification (with scores of ≥2.0) for 110 samples (96%). An in-house prepared database was constructed from 106 independent species, except for overlapping identifications. We used 48 wild mushrooms that were collected in autumn 2015 to validate the in-house database. As a result, 21 mushrooms were identified at the species level with

  7. Endodontic Surgery of a Deviated Premolar Root in the Surgical Orthodontic Management of an Impacted Maxillary Canine.

    Science.gov (United States)

    Pedullà, Eugenio; Valentino, Jessica; Rapisarda, Silvia

    2015-10-01

    Maxillary canine impactions are of multifactorial etiology. The incidence of maxillary canine impaction ranges from 1% to 4%. One of the reasons for canine impaction might be a deviated premolar root. This report describes surgical-orthodontic extrusion of an upper canine that occurred only after the endodontic surgery treatment of the adjacent deviated premolar root. Orthograde endodontic treatment followed by endodontic surgery with retrograde filling of the deviated premolar root was performed to obtain a surgical-orthodontic extrusion of the upper canine. A female patient, aged 15 years, with a class I molar relationship was referred to continue the orthodontic therapy. Although a correct surgical-orthodontic extrusion with adequate anchorage was carried out, the maxillary left canine had not erupted. Radiographic examination showed a deviated palatal root of the adjacent maxillary first premolar in the canine eruption path. Root canal filling followed by endodontic surgery of the first premolar deviated root has led to rapid progression of the canine and its placement in the arch in just 3 months. A multidisciplinary management involving endodontic treatment, endodontic surgery, and surgical-orthodontic extrusion could be considered a successful approach in the maxillary impacted canine cases in which adjacent premolar root is deviated. Long-term radiographic follow-up (6 years) indicated stable periodontal health of the canine and premolar without the presence of root resorption. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) for rapid identification of micro-organisms in the routine clinical microbiology laboratory.

    Science.gov (United States)

    Wattal, C; Oberoi, J K; Goel, N; Raveendran, R; Khanna, S

    2017-05-01

    The study evaluates the utility of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) Vitek MS for identification of microorganisms in the routine clinical microbiology laboratory. From May 2013 to April 2014, microbial isolates recovered from various clinical samples were identified by Vitek MS. In case of failure to identify by Vitek MS, the isolate was identified using the Vitek 2 system (bioMerieux, France) and serotyping wherever applicable or otherwise by nucleic acid-mediated methods. All the moulds were identified by Lactophenol blue mounts, and mycobacterial isolates were identified by molecular identification systems including AccuProbe (bioMerieux, France) or GenoType Mycobacterium CM (Hain Lifescience, Germany). Out of the 12,003 isolates, the Vitek MS gave a good overall ID at the genus and or species level up to 97.7% for bacterial isolates, 92.8% for yeasts and 80% for filamentous fungi. Of the 26 mycobacteria tested, only 42.3% could be identified using the Saramis RUO (Research Use Only) database. VITEK MS could not identify 34 of the 35 yeast isolates identified as C. haemulonii by Vitek 2. Subsequently, 17 of these isolates were identified as Candida auris (not present in the Vitek MS database) by 18S rRNA sequencing. Using these strains, an in-house superspectrum of C. auris was created in the VITEK MS database. Use of MALDI-TOF MS allows a rapid identification of aerobic bacteria and yeasts in clinical practice. However, improved sample extraction protocols and database upgrades with inclusion of locally representative strains is required, especially for moulds.

  9. Rapid and simple analysis of disease-associated biomarkers of Taiwanese patients with schizophrenia using matrix-assisted laser desorption ionization mass spectrometry.

    Science.gov (United States)

    Huang, Tiao-Lai; Lo, Li-Hua; Shiea, Jentaie; Su, Hung

    2017-10-01

    Matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF MS) is an extremely sensitive analytical tool for characterizing biological compounds in bio samples. In this study, we applied MALDI-TOF MS to assess potential protein biomarkers in the peripheral blood mononuclear cells (PBMCs) of patients with schizophrenia in the acute phase, recovery phase and healthy controls in Taiwan. We recruited 40 participants, including 20 pairs of patients diagnosed with schizophrenia in the acute phase, after four-week treatment with drug in the recovery phase, and 20 healthy controls. The schizophrenic patients were diagnosed using Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), and severity was assessed by a positive and negative symptom scale at baseline and at endpoint following four-week treatment with drug. The patients' PBMCs biomarkers were rapidly measured using a technique that combines MALDI-TOF MS and principle component analysis. A receiver operating characteristic curve was created for the evaluated biomarker. Significant differences in α-defensins 1-3 were found between the patients in acute phase with schizophrenia and the healthy controls, but not between the schizophrenic patients in recovery phase and healthy controls or between the schizophrenic patients in acute phase and in recovery phase. α-Defensins can be biomarkers of Taiwanese patients with schizophrenia, thus supporting the hypothesis that the inflammatory response and immunity system is correlated with the pathophysiology of schizophrenia. Moreover, the result also implies that α-defensins may be related in schizophrenia-associated disease not in efficacy of drug-treatment. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Rapid and sensitive serum glucose determination using chemical labeling coupled with black phosphorus-assisted laser desorption/ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Wang, Qing; Yu, Lei; Qi, Chu-Bo; Ding, Jun; He, Xiao-Mei; Wang, Ren-Qi; Feng, Yu-Qi

    2018-01-01

    Monitoring the concentration of blood glucose in patients is a key component of good medical diagnoses. Therefore, developing an accurate, rapid and sensitive strategy for monitoring blood glucose is of vital importance. We proposed a strategy for serum glucose determination combining 2-(4-boronobenzyl) isoquinolin-2-ium bromide chemical labeling with black phosphorus assisted laser desorption ionization-time of flight mass spectrometry (CL-BP/ALDI-TOF MS). The entire analytical process consisted of 1min of protein precipitation and 3min of chemical labeling in a microwave oven prior to the BP/ALDI-TOF MS analysis. The analysis can be completed in 5min with high throughput and extremely low sample consumption. Good linearity for glucose was obtained with a correlation coefficient (R) of 0.9986. The limit of detection (LOD) and limit of quantification (LOQ) were 11.5 fmol and 37.5 fmol, respectively. Satisfied reproducibility and reliability were gained by evaluation of the intra- and inter-day precisions with relative standard deviations (RSDs) less than 7.2% and relative recoveries ranging from 87.1% to 108.1%, respectively. The proposed strategy was also applied for the analysis of endogenous glucose in various serum samples and the results were consistent with those obtained using the hexokinase method in a clinical laboratory. Considering the results, the proposed CL-BP/ALDI-TOF MS strategy has proven to be reliable, fast, and sensitive for quantitative analysis of serum glucose. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. MoS2-Nanosheet-Assisted Coordination of Metal Ions with Porphyrin for Rapid Detection and Removal of Cadmium Ions in Aqueous Media.

    Science.gov (United States)

    Yin, Wenyan; Dong, Xinghua; Yu, Jie; Pan, Jun; Yao, Zhiyi; Gu, Zhanjun; Zhao, Yuliang

    2017-06-28

    Molybdenum disulfide (MoS2) is a two-dimensional (2D) graphene-like material that is gaining great attention because of its potential application in various fields. Here, we reported a self-assembled nanocomposite consisted of MoS2 nanosheets and 5,10,15,20-tetrakis(1-methyl-4-pyridinio)porphyrintetra(p-toluenesulfonate) (TMPyP), named MoS2@TMPyP. This nanocomposite can be used as a sensing probe for low cost, rapid, selective detection of cadmium (Cd(2+)) ions. It is found that a new Soret band at 442 nm in UV-vis absorption spectra represented the coordination of Cd(2+) ions into TMPyP of the MoS2@TMPyP. The coordination rates between TMPyP and Cd(2+) ions is greatly accelerated from 72 h to 20 min with the assistance of MoS2, which is 200 times faster than in the absence of MoS2. The limit of detection (LOD) of the Cd(2+) is as low as 7.2 × 10(-8) mol/L. The binding behavior between the cationic TMPyP and MoS2 nanosheets was corroborated by molecular dynamics simulation and various control experiments. The results demonstrated that electrostatic interaction was the main force for driving TMPyP enriching around the MoS2 surface, resulting in an accelerated complexation of Cd(2+) and TMPyP. Moreover, MoS2@TMPyP nanocomposite can also be used for removing of Cd(2+) in water. The removal efficiency (RF) of the MoS2@TMPyP can reach to 91% for high concentrations of Cd(2+). This work provides a new insight into detection and removal of Cd(2+) ions in water.

  12. Ultrasonic assisted rapid synthesis of high uniform super-paramagnetic microspheres with core-shell structure and robust magneto-chromatic ability

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wenyan, E-mail: wiseyanyan@jit.edu.cn [College of Material Engineering, Jinling Institute of technology, Nanjing (China); Chen, Jiahua [College of Material Engineering, Jinling Institute of technology, Nanjing (China); Wang, Wei [Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, Nanjing Tech University, Nanjing (China); School of Physics and Optoelectronic Engineering, Nanjing University of Information Science & Technology, Nanjing (China); Lu, GongXuan [State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000 (China); Hao, Lingyun [College of Material Engineering, Jinling Institute of technology, Nanjing (China); Ni, Yaru; Lu, Chunhua; Xu, Zhongzi [Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, Nanjing Tech University, Nanjing (China); State Key Laboratory of Materials-Oriented Chemical Engineering, College of Materials Science and Engineering, Nanjing Tech University, Nanjing (China)

    2017-03-15

    Super-paramagnetic core-shell microspheres were synthesized by ultrasonic assisted routine under low ultrasonic irradiation powers. Compared with conventional routine, ultrasonic effect could not only improve the uniformity of the core-shell structure of Fe{sub 3}O{sub 4}@SiO{sub 2}, but shorten the synthesis time in large scale. Owing to their hydrophilicity and high surface charge, the Fe{sub 3}O{sub 4}@SiO{sub 2} microspheres could be dispersed well in distilled water to form homogeneous colloidal suspension. The suspensions have favorable magneto-chromatic ability that they sensitively exhibit brilliant colorful ribbons by magnetic attraction. The colorful ribbons, which distributed along the magnetic lines, make morphology of the magnetic fields become “visible” to naked eyed. Those colorful ribbons originate from strong magnetic interaction between the microspheres and magnetic fields. Furthermore, the magneto-chromatic performance is reversible as the colorful ribbons vanished rapidly with the removing of magnetic fields. The silica layer effectively enhanced the acid resistance and surface-oxidation resistance of theFe{sub 3}O{sub 4}@SiO{sub 2} microspheres, so they could exhibit stable magnetic nature and robust magneto-chromatic property in acid environment. - Graphical abstract: The Graphical abstract shows the sensitive magneto-chromatic ability, the acid resistance ability as well as the magneto-chromatic mechanism of the Fe{sub 3}O{sub 4} and Fe{sub 3}O{sub 4}@SiO{sub 2} suspension. - Highlights: • Sensitive and reversible robust magneto-chromatic property under magnetic attraction. • Morphology of magnetic field “visible” to naked eyes. • Enhance acid resistance and surface-oxidation resistance. • Ultrasonic effect largely shorten the synthesis time of high uniform microspheres.

  13. Reliable and reproducible method for rapid identification of Nocardia species by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

    Science.gov (United States)

    Toyokawa, Masahiro; Kimura, Keigo; Nishi, Isao; Sunada, Atsuko; Ueda, Akiko; Sakata, Tomomi; Asari, Seishi

    2013-01-01

    Recently, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been challenged for the identification of Nocardia species. However, the standard ethanol-formic acid extraction alone is insufficient in allowing the membrane proteins of Nocardia species to be ionized by the matrix. We therefore aimed to establish our new extraction method for the MALDI-TOF MS-based identification of Nocardia species isolates. Our modified extraction procedure is through dissociation in 0.5% Tween-20 followed by bacterial heat-inactivation, mechanical breaking of the cell wall by acid-washed glass beads and protein extraction with formic acid and acetonitrile. As reference methods for species identification, full-length 16S rRNA gene sequencing and some phenotypical tests were used. In a first step, we made our own Nocardia database by analyzing 13 strains (13 different species including N. elegans, N. otitidiscaviarum, N. asiatica, N. abscessus, N. brasiliensis, N. thailandica, N. farcinica, N. nova, N. mikamii, N. cyriacigeorgica, N. asteroids, Nocardiopsis alba, and Micromonospora sp.) and registered to the MALDI BioTyper database. Then we established our database. The analysis of 12 challenge strains using the our database gave a 100% correct identification, including 8 strains identified to the species level and 4 strains to the genus level (N. elegans, N. nova, N. farcinica, Micromonospora sp.) according to the manufacture's log score specifications. In the estimation of reproducibility of our method intended for 4 strains, both within-run and between-run reproducibility were excellent. These data indicates that our method for rapid identification of Nocardia species is with reliability, reproducibility and cost effective.

  14. Impact of rapid microbial identification directly from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry on patient management.

    Science.gov (United States)

    Martiny, D; Debaugnies, F; Gateff, D; Gérard, M; Aoun, M; Martin, C; Konopnicki, D; Loizidou, A; Georgala, A; Hainaut, M; Chantrenne, M; Dediste, A; Vandenberg, O; Van Praet, S

    2013-12-01

    For septic patients, delaying the initiation of antimicrobial therapy or choosing an inappropriate antibiotic can considerably worsen their prognosis. This study evaluated the impact of rapid microbial identification (RMI) from positive blood cultures on the management of patients with suspected sepsis. During a 6-month period, RMI by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was performed for all new episodes of bacteraemia. For each patient, the infectious disease specialist was contacted and questioned about his therapeutic decisions made based on the Gram staining and the RMI. This information was collected to evaluate the number of RMIs that led to a therapeutic change or to a modification of the patient's general management (e.g. fast removal of infected catheters). During the study period, 277 new episodes of bacteraemia were recorded. In 71.12% of the cases, MALDI-TOF MS resulted in a successful RMI (197/277). For adult and paediatric patients, 13.38% (21/157) and 2.50% (1/40) of the RMIs, respectively, resulted in modification of the treatment regimen, according to the survey. In many other cases, the MALDI-TOF MS was a helpful tool for infectious disease specialists because it confirmed suspected cases of contamination, especially in the paediatric population (15/40 RMIs, 37.50%), or suggested complementary diagnostic testing. This study emphasizes the benefits of RMI from positive blood cultures. Although the use of this technique represents an extra cost for the laboratory, RMI using MALDI-TOF MS has been implemented in our daily practice. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

  15. Rapid Profiling of Bovine and Human Milk Gangliosides by Matrix-Assisted Laser Desorption/Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.

    Science.gov (United States)

    Lee, Hyeyoung; An, Hyun Joo; Lerno, Larry A; German, J Bruce; Lebrilla, Carlito B

    2011-08-15

    Gangliosides are anionic glycosphingolipids widely distributed in vertebrate tissues and fluids. Their structural and quantitative expression patterns depend on phylogeny and are distinct down to the species level. In milk, gangliosides are exclusively associated with the milk fat globule membrane. They may participate in diverse biological processes but more specifically to host-pathogen interactions. However, due to the molecular complexities, the analysis needs extensive sample preparation, chromatographic separation, and even chemical reaction, which makes the process very complex and time-consuming. Here, we describe a rapid profiling method for bovine and human milk gangliosides employing matrix-assisted desorption/ionization (MALDI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS). Prior to the analyses of biological samples, milk ganglioside standards GM3 and GD3 fractions were first analyzed in order to validate this method. High mass accuracy and high resolution obtained from MALDI FTICR MS allow for the confident assignment of chain length and degree of unsaturation of the ceramide. For the structural elucidation, tandem mass spectrometry (MS/MS), specifically as collision-induced dissociation (CID) and infrared multiphoton dissociation (IRMPD) were employed. Complex ganglioside mixtures from bovine and human milk were further analyzed with this method. The samples were prepared by two consecutive chloroform/methanol extraction and solid phase extraction. We observed a number of differences between bovine milk and human milk. The common gangliosides in bovine and human milk are NeuAc-NeuAc-Hex-Hex-Cer (GD3) and NeuAc-Hex-Hex-Cer (GM3); whereas, the ion intensities of ganglioside species are different between two milk samples. Kendrick mass defect plot yields grouping of ganglioside peaks according to their structural similarities. Gangliosides were further probed by tandem MS to confirm the compositional and structural assignments

  16. Evaluation of a new rapid readout biological indicator for use in 132°C and 135°C vacuum-assisted steam sterilization cycles.

    Science.gov (United States)

    Schneider, Philip M

    2014-02-01

    Sterilization is a process that cannot be inspected or tested in a practical manner to assure that all microorganisms have been inactivated. The process must therefore be validated for all of the specific items processed or monitored on a per cycle basis. A new, faster rapid readout biological indicator (RRBI) has been developed for use in 132°C and 135°C vacuum-assisted steam sterilization cycles. The aim of this study was to evaluate the performance of this new 1-hour readout RRBI at 132°C in side-by-side testing with an existing 3-hour readout RRBI and also evaluate the performance of the new RRBI in 135°C cycles. Readout responses of 1 hour (fluorescent) and 48 hours and 7 days (growth) of the new RRBI were compared with 3-hour, 48-hour, and 7-day readouts of the 3-hour RRBI following exposures in 132°C cycles using a highly controlled test vessel, ie, a steam resistometer. Additional testing of the 1-hour RRBIs was also performed in 135°C cycles. The number and percentage of fluorescent-positive 1-hour RRBIs were virtually identical to those of the 3-hour RRBIs after 1 and 3 hours of incubation, respectively. Testing of the 1-hour RRBI in 135°C cycles paralleled the results of the testing at 132°C but with the expected shorter exposure times. The results of this study suggest that the 1-hour RRBI is equivalent to the 3-hour RRBI and would be suitable for use in monitoring dynamic air removal steam sterilization cycles at both 132°C and 135°C per recommended practice guidelines. Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  17. Treatment of Bi-maxillary Protrusion with Impacted Maxillary and Mandibular Canines: Case Report.

    Science.gov (United States)

    Shdrma, Vipul Kumar; Yadav, Kirti; Nagar, Amit; Tandon, Pradeep; Chaturvedi, Thakur Prasad

    2016-01-01

    Bi-maxillary protrusion in adolescent patients has traditionally been treated by extraction of the four first premolars and retraction ofthe anterior teeth. The ectopic eruption of the maxiIlary permanent canines is a frequently encountered clinical problem. Orthodontic treatment of the impacted teeth remains a challenge for clinicians. If it is associated with other dental and skeletalproblems, there will be further complications to the treatment plan. In such cases, if we extract canines, then problems with this approach are restricted to anatomical and functional limitations ofpremolars substitution of canines. Here, we are presenting a case report of bi-maxillary dento-alveolar protrusion with the impacted maxillary and mandibular left canines and its management.

  18. Analysis digital panoramic radiograph about positions root of maxillary posterior teeth with maxillary sinus floor

    Directory of Open Access Journals (Sweden)

    Aprilia Dian Pertiwi

    2016-11-01

    Full Text Available Introduction: Maxillary sinus floor is a part of the alveolar bone adjacent to the apex of the posterior maxillary teeth that often causes complications in dentistry. Anatomical relationship between the maxillary posterior tooth root and the maxillary sinus floor can be obtained by panoramic radiograph.  The purpose of this study is to analysis digital panoramic radiograph about positions root of maxillary posterior teeth’s with  maxillary sinus floor by age and gender using. Methods: Research method is descriptive with purposive sampling technique. Study population was taken from archives of patient’s digital panoramic radiograph in Radiography Installation from January to March 2016. 88 samples were obtained from 207 digital panoramic radiographs archives. Results: The result showed that type 3 was dominated by P1 (86.8% right, 88.2% left, type 2 is dominated by P2 (24.7% right, 21% left, type 1 is dominated by M2 in the right (31.2% and M1 in the left (38.1%. Conclusion: This study concludes that overall, the most commonly found was type 3. Based on the age, type 1 majority occurs in age group of above 49 years old; type 2 in age group of 40-49 years old; and type 3 in age group 30-39 years old, 40-49 years old, and above 49 years old. By gender, type 1 and type 2 are more common in males, while type 3 is more common in female.

  19. Ecological and phylogenetic influences on maxillary dentition in snakes

    Directory of Open Access Journals (Sweden)

    Kate Jackson

    2010-12-01

    Full Text Available The maxillary dentition of snakes was used as a system with which to investigate the relative importance of the interacting forces of ecological selective pressures and phylogenetic constraints indetermining morphology. The maxillary morphology of three groups of snakes having different diets, with each group comprising two distinct lineages — boids and colubroids — was examined. Our results suggest that dietary selective pressures may be more significantthan phylogenetic history in shaping maxillary morphology.

  20. Does maxillary arch remodeling exist in nasal polyposis?

    Science.gov (United States)

    Gunhan, Kivanc; Can, Fatma; Uz, Uzdan; Serter, Selim; Unlu, Halis

    2010-01-01

    The potential transformation in the maxillary complex morphology is mostly complete during childhood. Recent studies suggest a nasal tissue remodeling both in the overlying mucosa and in the underlying sinus bone in nasal polyposis (NP). Our evaluation of computed tomography (CT) revealed that the maxillary arch is more flat and shallow in patients with chronic rhinosinusitis with NP. The purpose of this study was to determine the possible effects of NP to the maxillary arch morphology in adulthood and to investigate a possible remodeling of the maxillary bone during the course of NP. A prospective study was performed on 25 patients. Grading of the polyps, acoustic rhinometry and rhinomanometry assessments, and CT scans were documented initially, 1 year after diagnosis, and 2 years postoperatively. Twenty-five subjects' CT scans randomly selected from our CT database formed the comparison group. The plane angle between the maxillary alveolar processes (MAP) and the palatine process of the maxillary bone (MPP), and the depth of the maxillary arch of both groups were compared. The results pointed out that the maxillary arch was shallower and the bilateral angles between MAP and MPP were significantly greater than those of the comparison group in all evaluation periods. This difference was less at the end of the postoperative follow-up period. Although it is a common belief that maxillofacial formation expires in childhood, this may not be the case under some special conditions such as NP in adulthood. NP might cause maxillary arch remodeling in adults.

  1. Keratocystic odontogenic tumor with impacted maxillary third molar involving the right maxillary antrum:An unusual case report

    Directory of Open Access Journals (Sweden)

    Abhishek Gupta

    2011-01-01

    Full Text Available The odontogenic keratocyst (OKC, first described by Phillipsen in 1956, has metamorphosized as a keratocystic odontogenic tumor (KCOT as reported in WHO classification of head and neck tumors in 2005. KCOT is a benign intraosseous neoplasm of the jaw and its occurrence in maxilla is unusual and its appearance in maxillary antrum along with maxillary impacted third molar is very uncommon. This article reports a case of KCOT associated with impacted maxillary third molar in right maxillary antrum and describes its rare site of occurrence.

  2. Keratocystic odontogenic tumor with impacted maxillary third molar involving the right maxillary antrum: an unusual case report.

    Science.gov (United States)

    Gupta, Abhishek; Rai, Bhagavandas; Nair, Manju A; Bhut, Mitul K

    2011-01-01

    The odontogenic keratocyst (OKC), first described by Phillipsen in 1956, has metamorphosized as a keratocystic odontogenic tumor (KCOT) as reported in WHO classification of head and neck tumors in 2005. KCOT is a benign intraosseous neoplasm of the jaw and its occurrence in maxilla is unusual and its appearance in maxillary antrum along with maxillary impacted third molar is very uncommon. This article reports a case of KCOT associated with impacted maxillary third molar in right maxillary antrum and describes its rare site of occurrence.

  3. The primary Maxillary Central Incisor in the Solitary Median Maxillary Central Incisor syndrome

    DEFF Research Database (Denmark)

    Kjaer, I; Balslev-Olesen, M

    2012-01-01

    Solitary Median Maxillary Central Incisor (SMMCI) is a developmental anomaly in the permanent dentition with one single central incisor in the maxilla, positioned exactly in the midline. This condition has been associated with extra- and intraoral malformations in the frontonasal segment of the c...

  4. Treatment for an endosseous implant migrated into the maxillary sinus not causing maxillary sinusitis : Case report

    NARCIS (Netherlands)

    Raghoebar, GM; Vissink, A

    2003-01-01

    Placement of endosseous implants in the maxilla has been proven to be a reliable treatment modality. If there is lack of supporting bone, the placed implant may not have enough primary stability and may migrate into the maxillary sinus. Displaced implants must be removed. If there are no signs of

  5. A moderate dose of propofol and rapidly induced mild hypothermia with extracorporeal lung and heart assist (ECLHA) improve the neurological outcome after prolonged cardiac arrest in dogs.

    Science.gov (United States)

    Ichinose, Keisuke; Okamoto, Taisuke; Tanimoto, Hironari; Taguchi, Hiroyuki; Tashiro, Masafumi; Sugita, Michiko; Takeya, Motohiro; Terasaki, Hidenori

    2006-08-01

    Propofol has been shown to protect against neuronal damage induced by brain ischaemia in small animal models. We reported previously that mild hypothermia (33 degrees C) in combination with extracorporeal lung and heart assist (ECLHA) improved the neurological outcome in dogs with cardiac arrest (CA) of 15 min induced during normothermia. In the present study, we investigated the neuroprotective effect of propofol infusion under mild hypothermia with ECLHA in this model. Twenty-one female dogs (15 mongrel dogs and 6 beagles) were divided into three groups: Midazolam 0.1 mg/(kg h) infusion group (M, n=7), Propofol 2 mg/(kg h) infusion group (P2, n=7), Propofol 4 mg/(kg h) infusion group (P4, n=7). Normothermic ventricular fibrillation (VF) was induced in all dogs for 15 min, followed by brief ECLHA and 168 h of intensive care. The drug infusion was initiated at a constant rate after the restoration of spontaneous circulation (ROSC) to 24 h. Mild hypothermia (33 degrees C) was maintained for 20 h. Neurological deficit scores (NDS: 0%=normal, 100%=brain death) were evaluated for neurological function from 33 to 168 h. One dog in the M group died, and the remaining dogs survived for 168 h. The P4 group showed better neurological recovery compared with the M group (48 h, 21+/-16% versus 32+/-15%; 72 h, 7+/-6% versus 25+/-11%; 96 h, 6+/-6% versus 21+/-6%; 120 h, 5+/-5% versus 20+/-6%; 144 h, 4+/-4% versus 20+/-6%; 168 h, 4+/-4% versus 20+/-6%, pdog in the P2 and three dogs in the P4 group achieved full neurological recovery (NDS: 0%). The number of intact pyramidal cells in the hippocampal CA1 was greater in the propofol groups than midazolam group (p<0.05). The combination of propofol infusion at a rate of 4 mg/(kg h), 24h and rapidly induced mild hypothermia (33 degrees C) with ECLHA might provide a successful means of cerebral resuscitation from CA.

  6. Correlation between transverse expansion and increase in the upper arch perimeter after rapid maxillary expansion Correlação entre expansão transversal e aumento no perímetro do arco dentário após disjunção maxilar

    Directory of Open Access Journals (Sweden)

    Cristiane Aparecida de Assis Claro

    2006-03-01

    Full Text Available The purpose of the present study was to assess the correlation between transverse expansion and the increase in upper arch perimeter, after maxillary expansion. Dental casts of eighteen patients were obtained before treatment and again five months after maxillary expansion. Measurements of intermolar width, intercanine width, arch length and arch perimeter were made with a digital caliper on photocopies taken from the dental casts. After assessment of the method error, a multiple regression model was developed following the identification of the best subset of variables. The resulting equation led to the conclusion that the increase in arch perimeter is approximately given by the addition of 0.54 times the intercanine expansion, and 0.87 times the arch length alteration.O presente estudo avaliou a correlação entre expansão transversal e aumento no perímetro do arco dentário superior, após disjunção maxilar, em dezoito pares de modelos de gesso, obtidos antes e depois de aproximadamente cinco meses da disjunção maxilar. Os modelos foram fotocopiados e as variáveis largura intermolares, largura intercaninos, comprimento e perímetro do arco dentário superior foram mensuradas por meio de paquímetro digital. Depois de verificado o erro do método, um modelo de regressão múltipla foi desenvolvido em seqüência à identificação do melhor conjunto de variáveis. A equação resultante permitiu concluir que o aumento no perímetro do arco é dado pela adição de 0,54 vezes a alteração intercaninos e de 0,87 vezes a alteração no comprimento do arco.

  7. Expansão cirúrgica da maxila Surgical maxillary expansion

    Directory of Open Access Journals (Sweden)

    Eduardo Sant'Ana

    2009-10-01

    Full Text Available Embora a expansão rápida da maxila possa ser considerada um procedimento ortodôntico eficaz e amplamente utilizado na correção da deficiência transversa maxilar em crianças e pacientes adolescentes jovens, seu prognóstico não se apresenta muito favorável na correção dessa condição oclusal em pacientes adultos ou no final da adolescência. Nesses pacientes, a correção da deficiência transversa pode ser realizada com sucesso através da intervenção cirúrgica, seja por meio da expansão assistida ou da osteotomia multissegmentada da maxila.Although the maxillary expansion may be considered a orthodontic procedure efficient and widely used in the maxillary transverse deficiency correction in children and young adolescent patients, its prognostic is not very favorable in the correction of this occlusal condition in adults or patients in the adolescence end. In these patients the correction of this transverse deficiency may be successfully conducted by means of the surgical intervention, either through the assisted expansion or the multi-segmented maxillary osteotomy.

  8. Compound odontoma associated with impacted maxillary incisors

    Directory of Open Access Journals (Sweden)

    S Sreedharan

    2012-01-01

    Full Text Available Odontomas are considered to be the most common odontogenic tumors of the oral cavity. Some authors consider it as malformations rather than true neoplasms. The exact etiology of odontomes is still not known. Most odontomes are asymptomatic and are discovered during routine radiographic investigations. Odontomes generally cause disturbances in the eruption of the teeth, most commonly delayed eruption or deflection. The present report describes the surgical management of a case of compound odontoma in a 10-year-old boy who presented with a complaint of swelling in the maxillary right anterior region and retained deciduous incisors. The related literature is also being reviewed in this article.

  9. Supernumerary maxillary and Mandibular Fourth Molars.

    Science.gov (United States)

    1981-09-23

    Company. 12. Luten, J.R.: The prevalence of supernumerary teeth in primary and mixed dentitions . J Dent Child 9:346-353, 1967. LEGEND Fig 1 Impacted...aide it n~coaesny and Identify by block number) Supernumerary teeth sk 1 AT waAC? V0111i (Cae s evem h N 011,690411 - idetit7 by block ntmmba) Five cases...of patients having supernumerary teeth in the distomolar regions of the mandibula and maxillary arches are reported. Supernumerary bicuspids were

  10. Wing-bib multi helix maxillary expander

    Directory of Open Access Journals (Sweden)

    Mugdha P Mankar

    2017-01-01

    Full Text Available An orthodontic appliance for maxillary expansion is presented, which consists of a wire assembly fabricated from 0.032” round straight length beta-titanium wire. Posterior active portion of the appliance consists of a trihelix omega loop parallel to palatal surface, providing transverse expansion and distalizing forces on the first molars. Anterior active portion consisting of an acrylic apron (bib over a (wing-like wire framework, provides transverse expansion at the anterolateral slopes of the palate including the depths; lying directly over the envisioned canine- first premolar root area of the palatal vault surface.

  11. Maxillary osteosarcoma in a beef suckler cow

    Directory of Open Access Journals (Sweden)

    Prins Diether G J

    2012-07-01

    Full Text Available Abstract A ten-year-old beef suckler cow was referred to the Scottish Centre for Production Animal Health & Food Safety of the University of Glasgow, because of facial swelling in the region of the right maxilla. The facial swelling was first noticed three months earlier and was caused by a slow growing oral mass which contained displaced, loosely embedded teeth. The radiographic, laboratory and clinicopathological findings are described. Necropsy, gross pathology and histological findings confirmed the mass as a maxillary osteosarcoma.

  12. Internal root morphology in maxillary first permanent molars in a ...

    African Journals Online (AJOL)

    Objective: To determine the internal root morphology and gender variations in maxillary first permanent molars in a Kenyan population. Design: In vitro descriptive cross-sectional study. Setting: School of Dental Sciences, University of Nairobi. Subject: One hundred and eighty seven maxillary first permanent molars were ...

  13. External root morphology of maxillary first premolars in Kenyan ...

    African Journals Online (AJOL)

    Objective: To determine the external root morphology of the maxillary first premolars in Kenyan Africans. Design: In vitro descriptive cross-sectional study. Setting: School of Dental Sciences, University of Nairobi. Subjects: One hundred and fifty five extracted maxillary first premolar teeth obtained from patients aged between ...

  14. Maxillary Ameloblastoma: An Enigma for the Surgeon. | Ajike ...

    African Journals Online (AJOL)

    Background: Ameloblastoma is a benign but locally aggressive odontogenic tumour. Worldwide, maxillary ameloblastoma is rare but its late detection renders adequate treatment difficult. Majority occur in the mandible with about 5-20% occurring in the maxillary bone. Objective: The purpose of this study was to analyze 21 ...

  15. Prosthetic Rehabilitation of Patients with Maxillary Defects in a ...

    African Journals Online (AJOL)

    Conclusion: The results of this study suggest that majority of the obturators fabricated for patients with maxillary defect at the Tertiary health institution in Nigeria were immediate surgical obturators. Pre‑surgical patient education and follow‑up care is advocated. Keywords: Maxillary defects, Maxillectomy, Obturators ...

  16. Maxillary arch and combined incisor dimensions of Urhobos in ...

    African Journals Online (AJOL)

    Tooth morphometry is known to be influenced by cultural, environment and racial or ethnic factors. The purpose of this study was to assess the maxillary arch and combined incisor widths; to determine if there is sexual dimorphism in the maxillary arch and combined incisor dimensions; to verify the reliability of Pont's Index ...

  17. Orthodontic management of an impacted maxillary central incisor ...

    African Journals Online (AJOL)

    The orthodontic management of an impacted maxillary central incisor with a talon cusp and dilacerated root in a 23-year-old female is reported. The patient presented complaining of an inability to smile because of the irregular arrangement of her front teeth. An oral examination revealed absence of the maxillary right ...

  18. Maxillary incisor root forms in orthodontic patients in Nairobi, Kenya ...

    African Journals Online (AJOL)

    Objective:To evaluate, radiographically, the root forms of maxillary incisors in a sample of patients seeking orthodontic treatment in Nairobi, Kenya. Design:A retrospective study of maxillary incisor root forms based on periapical radiographs. Setting: A private dental clinic in Nairobi, Kenya. Materials and Methods:The study ...

  19. CASE REPORT - Maxillary Herpes Zoster with Corneal Involvement ...

    African Journals Online (AJOL)

    Corneal involvement in maxillary herpes zoster is very rare. This report presents the case of a 32 years old 7 months pregnant para2+1 female, who presented with vesiculopapular rashes with hyperpigmented crusts over the maxillary area of the face on the left side with periocular oedema, conjunctivitis and mild punctate ...

  20. Maxillary First Premolar with Three Root Canals: A Case Report ...

    African Journals Online (AJOL)

    ... the tooth is needed to ensure a proper endodontic treatment. This article reports a rare finding of three canals in a maxillary first premolar with non well defined root outline radiographically during an elective root canal treatment. Keywords: Maxillary First Premolar, Endodontic Treatment, Elective, Root Canal Morphology ...

  1. Classification of Alveolar Bone Destruction Patterns on Maxillary ...

    African Journals Online (AJOL)

    2017-09-14

    Sep 14, 2017 ... implant can be prevented in many cases and be replaced with a more conservative approach on the maxillary molar region. .... maxillary sinus elevation and bone augmentation are usually needed to increase the ...... they are narrow and deep, may be successfully treated with techniques that attempt new ...

  2. Odontogenic sinusitis: an ancient but under-appreciated cause of maxillary sinusitis.

    Science.gov (United States)

    Patel, Nimish A; Ferguson, Berrylin J

    2012-02-01

    For well over 100 years, it has been appreciated that maxillary dental infections can cause sinusitis. This insight has been largely overlooked with the advent of functional endoscopic sinus surgery (ESS) and its emphasis on the osteomeatal complex. We review several recent case series and reviews of odontogenic sinusitis that characterize and discuss emerging diagnostic modalities in odontogenic sinusitis. In recent publications on odontogenic sinusitis, up to 40% of chronic bacterial maxillary sinus infections are attributed to a dental source, which is far higher than the previously reported incidence of 10%. Plain dental films and dental evaluations frequently fail to detect maxillary dental infection that can be causing odontogenic sinusitis. However, sinus computed tomography (CT) or Cone Beam Volumetric CT (CBVCT) are far more successful in identifying dental disease causing sinusitis. The microbial pathogens of odontogenic sinusitis remain unchanged from earlier reviews; however, the clinical findings in odontogenic sinusitis are better described in recent reviews. Successful treatment of odontogenic sinusitis requires management of the odontogenic source and may require concomitant or subsequent sinus surgery. Odontogenic sinusitis is frequently recalcitrant to medical therapy and usually requires treatment of the dental disease. Sometimes dental treatment alone is adequate to resolve the odontogenic sinusitis and sometimes concomitant or subsequent ESS is required. Evaluation of all patients with persistent chronic rhinosinusitis (CRS) should include inspection of the maxillary teeth on CT scan for evidence of periapical lucencies. Unilateral recalcitrant disease associated with foul smelling drainage is especially characteristic of odontogenic sinusitis. High-resolution CT scans and CBVCT can assist in identifying dental disease.

  3. Endodontic treatment of a geminated maxillary second molar using an endoscope as magnification device.

    Science.gov (United States)

    Weinstein, T; Rosano, G; Del Fabbro, M; Taschieri, S

    2010-05-01

    To describe endodontic treatment for a rare case of gemination. A case of complex endodontic treatment in a geminated tooth is presented. With the assistance of microinstruments and magnification devices, a geminated maxillary second molar was successfully treated. In such a case, ultrasonic tips and the use of an endoscope were essential to detect the peculiar anatomy of the tooth involved. Knowledge of anomalies concerning fused teeth is essential. Using an endoscope as a magnification device is useful during the inspection of pulp chambers. Ultrasonic tips are safe and useful to detect canal orifices.

  4. Aspergilloma of the maxillary sinus: report of a case

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Ju Han; Kim, Gyu Tae; Choi, Yong Suk; Hwang, Eui Hwan [School of Dentistry, Kung Hee University, Seoul (Korea, Republic of); Yu, Jae Jung [Kangdong Scared Heart Hospital, Hallym Medical Center, Seoul (Korea, Republic of)

    2010-12-15

    Aspergilloma of the paranasal sinus is a non-invasive form of aspergillosis, most often in the maxillary sinus. This case presents an 86-year-old female with aspergilloma of the left maxillary sinus. The patient's chief complaint was intermittent pain on the left maxillary first premolar area. A radiopacification of the left maxillary sinus was observed on the panoramic radiograph. Cone-beam computed tomography revealed complete radiopacification of the left maxillary sinus and scattered multiple radiopaque mass inside the lesion. Biopsy was performed under local anesthesia. On microscopic examination, numerous fungal hyphae, which branch at acute angle, were observed. The diagnosis was made as an aspergilloma based on the histopathologic examination.

  5. Surgical endodontic management of infected lateral canals of maxillary incisors.

    Science.gov (United States)

    Jang, Ji-Hyun; Lee, Jung-Min; Yi, Jin-Kyu; Choi, Sung-Baik; Park, Sang-Hyuk

    2015-02-01

    This case report presents surgical endodontic management outcomes of maxillary incisors that were infected via the lateral canals. Two cases are presented in which endodontically-treated maxillary central incisors had sustained lateral canal infections. A surgical endodontic treatment was performed on both teeth. Flap elevation revealed vertical bone destruction along the root surface and infected lateral canals, and microscopy revealed that the lateral canals were the origin of the lesions. After the infected lateral canals were surgically managed, both teeth were asymptomatic and labial fistulas were resolved. There were no clinical or radiographic signs of surgical endodontic management failure at follow-up visits. This case report highlights the clinical significance and surgical endodontic management of infected lateral canal of maxillary incisor. It is important to be aware of root canal anatomy variability in maxillary incisors. Maxillary central incisors infected via the lateral canal can be successfully managed by surgical endodontic treatment.

  6. Maxillary sinus carcinoma: result of radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Shibuya, H.; Horiuchi, J.; Suzuki, S.; Shioda, S.; Enomoto, S.

    1984-07-01

    This hundred and sixteen patients with carcinoma of the maxillary sinus received primary therapy consisting of external beam irradiation alone or in combination with surgery and/or chemotherapy at the Department of Radiology, Tokyo Medical and Dental University Hospital, between 1953 and 1982. In our institution, methods of treating cancer of the maxillary sinus have been changed from time to time and showed different control rates and clinical courses. An actuarial 10-year survival rate of 21% has been obtained by the megavoltage irradiation alone as well as 34% actuarial 10-year survival rate by megavoltage irradiation with surgery. After the introduction of conservative surgery followed by conventional trimodal combination therapy, the local control rate has been improved. The amount of functional, cosmetic, and brain damages have been remarkably decreased by this mode of therapy. The actuarial five year survival rate was 67%. In addition, along with the improvement of the local control rate, the control of nodal and distant organ metastases have been emerging as one of the important contributions to the prognosis of this disease.

  7. Maxillary dentoskeletal changes 1-year after adenotonsillectomy.

    Science.gov (United States)

    Brunelli, Valerio; Lione, Roberta; Franchi, Lorenzo; Cozza, Paola; Becker, Helena M G; Franco, Letícia P; Souki, Bernardo Q

    2016-07-01

    To measure the maxillary dentoskeletal and soft tissue changes of severely obstructed mouth breathing (MB) young children who had their mode of breathing normalized after adenotonsillectomy (T&A), in comparison with a matched group of severely obstructed untreated MB children (CG). Seventy patients who had an Ear, Nose, and Throat examination (ENT), including flexible nasal endoscopy, to confirm the severe obstruction of the upper airways and the indication of T&A composed the sample. Cephalograms and dental casts were available from the patient's orthodontic records. Treatment group (TG) and CG included 35 children each. Groups were matched by gender (24 males and 11 females in each group), age (TG, 6.7 ± 1.8 years; CG, 6.9 ± 2.3 years), tooth development (TG, 13 primary dentition, 22 mixed dentition; CG, 14 primary dentition, 21 mixed dentition), and skeletal maturation status. Records were taken at baseline (T0) and 1-year after T&A (T1) for TG; while CG records were taken with a 1-year interval. Dentoskeletal measurements were performed in the lateral cephalograms, and dental casts were used to assess the palatal volume and occlusal changes. TG showed a significant increase (503.3 mm(3), P palatal volume (10% of change), while CG palatal volume was stable. No dimensional occlusal changes were detected between T0 and T1 in both groups. Significant downward (point A, 2.1 mm; ANS, 2.1 mm) and forward displacements (point A, 0.7 mm; ANS, 1 mm) of the anterior region of the maxilla were observed in the TG, but CG presented only significant downward displacement (point A, 1.8 mm; ANS, 1.4 mm). The maxillary posterior region (PNS, PTM, and Molar) displaced downward in both groups (P palatal plane inclination was stable in both groups. TG presented significant increase in the palatal volume and in the forward displacement of the maxilla. No other significant maxillary dentoskeletal changes were found. Copyright © 2016 Elsevier Ireland Ltd

  8. CT-MPR invaluable in diagnosing odontogenic maxillary sinusitis

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, Hideaki; Shimazu, Kaoru; Kamada, Morito; Shiroyama, Akihiro; Mouri, Daisuke; Yamashita, Masashi; Kawasaki, Yasunori; Koseki, Takakazu; Mouri, Manabu [Osaka Dental Univ. (Japan)

    2001-08-01

    In everyday examination, it is usual to encounter odontogenic maxillary sinusitis patients. Odontogenic maxillary sinusitis is generally best diagnosed by dental X-ray imaging. Many medical facilities not having a dental X-ray unit use coronal computed tomography (CT) images to diagnose odontogenic maxillary sinusitis. Coronal CT imaging causes artifacts, however due to dental prosthesises. Computed tomography-Multiplanar reformation (CT-MPR) imaging has proved useful in evaluating the paranasal sinus because it is not influenced by dental prosthesises. We evaluated the usefulness of CT-MPR for diagnosing odontogenic maxillary sinusitis by retrospectively analyzing 16 patients, with the following results. We couldn't diagnose all cases of odontogenic maxillary sinusitis in posteroanterior and Waters projection images. Panoramic radiography is needed to diagnose odontogenic maxillary sinusitis. Dental X-ray imaging missed some cases, but all cases were diagnosed by CT-MPR imaging, giving a 100% diagnosestic rate. CT-MPR imaging is thus at least as valuable or better than dental X-ray imaging in diagnosing odontogenic maxillary sinusitis. (author)

  9. Association between maxillary sinus pathologies and healthy teeth

    Directory of Open Access Journals (Sweden)

    Gina D. Roque-Torres

    2016-02-01

    Full Text Available ABSTRACT INTRODUCTION: The proximity of the roots to the maxillary sinus can create a variety of risks. OBJECTIVE: To evaluate the relationship between the roots of healthy teeth and the maxillary sinus, as well as the occurrence of sinus pathologies. METHODS: Three radiologists analyzed 109 cone beam computed tomography (CBCT images. The Kappa test was used to assess the intra- and inter-rater agreement. The chi-squared test and prevalence ratio were used to test the hypothesis that roots of healthy teeth in the maxillary sinus favored the occurrence of sinus pathologies ( p = 0.01. RESULTS: Intra- and inter-rater agreement ranged from good to excellent. The chi-squared test demonstrated a statistically significant difference ( p = 0.006 between the tooth roots in diseased maxillary sinuses (6.09% and those in normal sinuses (3.43%. The prevalence ratio test showed a statistically significant higher prevalence of tooth roots in diseased sinuses than in normal sinuses ( p < 0.0001. Roots in the maxillary sinus were 1.82 times more associated with diseased sinuses. CONCLUSION: Dental roots in the maxillary sinus are almost twice as likely to be associated with diseased sinuses than normal sinuses. Healthy teeth whose roots are inside the maxillary sinus may induce an inflammatory response in the sinus membrane. It is suspected that dental procedures may exacerbate the condition.

  10. Endodontic working length of permanent maxillary central incisors in Nigerians.

    Science.gov (United States)

    Sede, M A; Oboro-Onuora, H O; Umanah, A U

    2013-01-01

    The permanent maxillary central incisors are critical to dento-facial aesthetics in humans. Their restoration in the event of periapical infection or traumatic injury to the pulp requires an accurate determination of the root canal working length; an important outcome predictor in endodontic treatments. To determine the standard working length of permanent maxillary central incisor in a Nigerian population. This study was carried out between March 2008 and June 2010. The study involved Nigerian patients of both gender, receiving endodontic treatment of the permanent maxillary central incisor. The study participants were selected based on a predetermined exclusion and inclusion criteria. The working lengths of the patient's teeth were determined using the radiographic method and Electronic apex locator. The average working length of the permanent maxillary central incisor of the patient's was 25.0 ± 1.7 mm while the values in males and females were 25.4 ± 1.2mm and 24.4 ± 2.2mm respectively. The male patients had longer working length than the females (P<0.05). The study also revealed that the most common indication for endodontic treatment in permanent maxillary central incisors in the studied population was trauma. The endodontic working length of permanent maxillary central incisors in adult Nigerian population was greater than that reported in Caucasians and Asians. This variation should serve as an important reference for endodontic procedures in the maxillary central incisors of adult Nigerians and perhaps others nationals from the West Africa sub region.

  11. Maxillary repositioning according to Frankfort horizontal plane during orthognathic surgery.

    Science.gov (United States)

    Ghoreishian, Mehdi; Hasheminia, Dariush; Hashemzehi, Hadi; Khazaei, Saber

    2013-01-01

    There are a lot of disagreements among surgeons over controlling the maxillary position during orthognathic surgery. To investigate maxillary repositioning according to Frankfort horizontal plane in orthognathic surgery. Fourteen patients were selected who were submitted to maxillary or bimaxillary surgery. Maxillary model surgery was performed based on the treatment planning and an intermediate splint was made. The surgical technique in this study was based on maxillary osteotomy according to the findings of the model surgery, in a manner that the osteotomy line was parallel to the Frankfort horizontal plane. Intermediate splint was used for repositioning of the maxilla in the new position and the vertical position of that was determined according to external reference point and fixed on this position. The upper central incisor designed from prediction tracing and post-operative cephalometry on the first tracing. The new position of maxilla was evaluated horizontally and vertically. A paired t-test was used to compare the predicted maxillary position and the actual position. Association between these two groups of variables was evaluated with Pearson correlation. The mean difference between the maxillary planned position and post-operative cephalometric radiography varied between 0.3 mm and 0.9 mm vertically (P value = 0.315) and 0.0 mm and 0.9 mm horizontally (P value = 0.034). The averages of horizontally and vertically observed changes were 0.3 mm and 0.17 mm respectively (P surgery. By eliminating the ramping effect the accuracy of surgery increases.

  12. Three-dimensional assessment of maxillary changes associated with bone anchored maxillary protraction

    Science.gov (United States)

    Nguyen, Tung; Cevidanes, Lucia; Cornelis, Marie A.; Heymann, Gavin; de Paula, Leonardo K.; De Clerck, Hugo

    2013-01-01

    Introduction Bone-anchored maxillary protraction has been shown to be an effective treatment modality for the correction of Class III malocclusions. The purpose of this study was to evaluate 3-dimensional changes in the maxilla, the surrounding hard and soft tissues, and the circummaxillary sutures after bone-anchored maxillary protraction treatment. Methods Twenty-five consecutive skeletal Class III patients between the ages of 9 and 13 years (mean, 11.10 ± 1.1 years) were treated with Class III intermaxillary elastics and bilateral miniplates (2 in the infrazygomatic crests of the maxilla and 2 in the anterior mandible). Cone-beam computed tomographs were taken before initial loading and 1 year out. Three-dimensional models were generated from the tomographs, registered on the anterior cranial base, superimposed, and analyzed by using color maps. Results The maxilla showed a mean forward displacement of 3.7 mm, and the zygomas and the maxillary incisors came forward 3.7 and 4.3 mm, respectively. Conclusions This treatment approach produced significant orthopedic changes in the maxilla and the zygomas in growing Class III patients. PMID:22133943

  13. Bilateral fusion of permanent maxillary incisors

    Directory of Open Access Journals (Sweden)

    Manoj Kumar Hans

    2011-01-01

    Full Text Available Dental fusion is a rare developmental anomaly, which is included in the anomalies of tooth morphology or shape. Fusion can occur at the level of enamel or enamel and dentin, which results in the formation of a single tooth with enlarged clinical crown. Fusion is more common in deciduous dentition. Incisors are reported to be fused in primary and permanent dentition, but bilateral fusion is a rare occurrence. The prevalence of bilateral fusion in the permanent dentition is less frequent than unilateral fusion and is reported to be around 0.05%. The authors report a case of a 20-year-old male with bilateral fusion of maxillary central and lateral incisors. Multi-disciplinary treatment approach is essential to get the desired esthetic result. The best way to manage these difficult cases depends on a number of factors including the knowledge and technical skills of the practitioner.

  14. Solitary median maxillary central incisor (SMMCI syndrome

    Directory of Open Access Journals (Sweden)

    Hall Roger K

    2006-04-01

    Full Text Available Abstract Solitary median maxillary central incisor syndrome (SMMCI is a complex disorder consisting of multiple, mainly midline defects of development resulting from unknown factor(s operating in utero about the 35th–38th day(s from conception. It is estimated to occur in 1:50,000 live births. Aetiology is uncertain. Missense mutation in the SHH gene (I111F at 7q36 may be associated with SMMCI. The SMMCI tooth differs from the normal central incisor, in that the crown form is symmetric; it develops and erupts precisely in the midline of the maxillary dental arch in both primary and permanent dentitions. Congenital nasal malformation (choanal atresia, midnasal stenosis or congenital pyriform aperture stenosis is positively associated with SMMCI. The presence of an SMMCI tooth can predict associated anomalies and in particular the serious anomaly holoprosencephaly. Common congenital anomalies associated with SMMCI are: severe to mild intellectual disability, congenital heart disease, cleft lip and/or palate and less frequently, microcephaly, hypopituitarism, hypotelorism, convergent strabismus, oesophageal and duodenal atresia, cervical hemivertebrae, cervical dermoid, hypothyroidism, scoliosis, absent kidney, micropenis and ambiguous genitalia. Short stature is present in half the children. Diagnosis should be made by eight months of age, but can be made at birth and even prenatally at 18–22 weeks from the routine mid-trimester ultrasound scan. Management depends upon the individual anomalies present. Choanal stenosis requires emergency surgical treatment. Short stature may require growth hormone therapy. SMMCI tooth itself is mainly an aesthetic problem, which is ideally managed by combined orthodontic, prosthodontic and oral surgical treatment; alternatively, it can be left untreated.

  15. Solitary median maxillary central incisor (SMMCI) syndrome.

    Science.gov (United States)

    Hall, Roger K

    2006-04-09

    Solitary median maxillary central incisor syndrome (SMMCI) is a complex disorder consisting of multiple, mainly midline defects of development resulting from unknown factor(s) operating in utero about the 35th-38th day(s) from conception. It is estimated to occur in 1:50,000 live births. Aetiology is uncertain. Missense mutation in the SHH gene (I111F) at 7q36 may be associated with SMMCI. The SMMCI tooth differs from the normal central incisor, in that the crown form is symmetric; it develops and erupts precisely in the midline of the maxillary dental arch in both primary and permanent dentitions. Congenital nasal malformation (choanal atresia, midnasal stenosis or congenital pyriform aperture stenosis) is positively associated with SMMCI. The presence of an SMMCI tooth can predict associated anomalies and in particular the serious anomaly holoprosencephaly. Common congenital anomalies associated with SMMCI are: severe to mild intellectual disability, congenital heart disease, cleft lip and/or palate and less frequently, microcephaly, hypopituitarism, hypotelorism, convergent strabismus, oesophageal and duodenal atresia, cervical hemivertebrae, cervical dermoid, hypothyroidism, scoliosis, absent kidney, micropenis and ambiguous genitalia. Short stature is present in half the children. Diagnosis should be made by eight months of age, but can be made at birth and even prenatally at 18-22 weeks from the routine mid-trimester ultrasound scan. Management depends upon the individual anomalies present. Choanal stenosis requires emergency surgical treatment. Short stature may require growth hormone therapy. SMMCI tooth itself is mainly an aesthetic problem, which is ideally managed by combined orthodontic, prosthodontic and oral surgical treatment; alternatively, it can be left untreated.

  16. Treatment of anastomotic leakage after rectal resection with transrectal vacuum-assisted drainage (VAC). A method for rapid control of pelvic sepsis and healing

    DEFF Research Database (Denmark)

    Nagell, Carl Frederik Otto; Holte, Kathrine

    2006-01-01

    functional result is not uncommon. Vacuum-assisted closure (VAC) has been shown to accelerate wound healing by increasing local blood flow, reducing bacterial load and stimulating growth of granulation tissue. In this paper, we describe VAC as a method for treating anastomotic leakage after rectal resection...

  17. Development of a Rapid and Accurate Identification Method for Citrobacter Species Isolated from Pork Products Using a Matrix-Assisted Laser-Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS).

    Science.gov (United States)

    Kwak, Hye-Lim; Han, Sun-Kyung; Park, Sunghoon; Park, Si Hong; Shim, Jae-Yong; Oh, Mihwa; Ricke, Steven C; Kim, Hae-Yeong

    2015-09-01

    Previous detection methods for Citrobacter are considered time consuming and laborious. In this study, we have developed a rapid and accurate detection method for Citrobacter species in pork products, using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). A total of 35 Citrobacter strains were isolated from 30 pork products and identified by both MALDI-TOF MS and 16S rRNA gene sequencing approaches. All isolates were identified to the species level by the MALDI-TOF MS, while 16S rRNA gene sequencing results could not discriminate them clearly. These results confirmed that MALDI-TOF MS is a more accurate and rapid detection method for the identification of Citrobacter species.

  18. Management of palato radicular groove in a maxillary lateral incisor

    National Research Council Canada - National Science Library

    Kishan, K V; Hegde, Vani; Ponnappa, K C; Girish, T N; Ponappa, M C

    2014-01-01

    This study is to report the rare localization of a radicular groove on the palatal aspect of the maxillary lateral incisor and to discuss the pathology and management of the concomitant endo-periodontal defect...

  19. The CT findings of maxillary sinusitis comparing with conventional radiography

    Energy Technology Data Exchange (ETDEWEB)

    Ohmori, Keiichi; Minowa, Kazuyuki; Kaneko, Masanori; Yamazaki, Michio (Hokkaido Univ., Sapporo (Japan). School of Dentistry); Hirano, Masayasu

    1991-04-01

    The CT findings of 42 patients with surgically verified benign lesions of the maxillary sinus were evaluated to demonstrate the value of CT. Comparison with conventional radiological methods was made. The opacification of the maxillary sinus lumen in Waters view shows the relationship in proportion to the soft tissue that occupies the sinus in CT finding. The thickening in the posterior wall of the maxillary antra may cause the opacification in Waters view. The Waters view can depict more significantly the maxillary soft tissue in CT finding than the Caldwell view and panoramic view. CT is of value in demonstration of fluid level, mucosal swelling, mucosal thickening and the thickening of the bony walls. (author).

  20. Localization of impacted maxillary canines using panoramic radiography

    National Research Council Canada - National Science Library

    Nagpal, Archna; Pai, Keerthilatha M; Setty, Suhas; Sharma, Gaurav

    2009-01-01

    We aimed to establish a reliable method of localizing an impacted maxillary canine on the sole basis of assessment of a single panoramic radiograph, and to determine the validity and reproducibility of the method...

  1. Oncologic profile of maxillary odontogenic myxoma: A rare case

    Directory of Open Access Journals (Sweden)

    Reena Radhikaprasad Sarkar

    2013-01-01

    Full Text Available Odontogenic myxoma (OM is an ectomesenchyme derived neoplasm, almost exclusively found in jaws. This article presents a maxillary OM with a brief review of the molecular and proteomic antecedents of OMs, capturing its histopathogenesis.

  2. Prosthetic Rehabilitation of Patients with Maxillary Defects in a ...

    African Journals Online (AJOL)

    com. Introduction. Maxillary defects are created by surgical treatment of benign or malignant neoplasms, congenital malformation and ... the orbital contents to prevent enophthalmos and diplopia, support of the soft-tissue to restore the midfacial ...

  3. Esthetics with prosthetics in case of maxillary canine transposition: A ...

    African Journals Online (AJOL)

    2011-03-16

    .app.medknow. For suggestions and comments do write back to us. Announcement. How to cite this article: Yadav S, Sheorain AK, Madan N, Bajaj P. Esthetics with prosthetics in case of maxillary canine transposition: A ...

  4. Radicular cyst of maxillary primary tooth: Report of two cases

    Directory of Open Access Journals (Sweden)

    Vinod Vijay Chander

    2014-01-01

    Full Text Available Radicular cyst is one of the most common odontogenic cysts of the jaws, but those arising from primary teeth are very rare. This article reports two such rare cases incidentally affecting deciduous maxillary teeth.

  5. A Case of Maxillary Bone Metastasis from Lung Cancer

    National Research Council Canada - National Science Library

    Kusunoki, Takeshi; Homma, Hirotomo; Kidokoro, Yoshinobu; Yanai, Aya; Ikeda, Katsuhisa; Wada, Ryo

    2015-01-01

    We experienced a very rare case of maxillary bone metastasis from lung cancer. The patient was a 77-year-old Japanese man with 1-month history of right alar swelling with hard pain as his chief complaint...

  6. Bilateral postoperative maxillary cysts after orthognathic surgery: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Hye; Huh, Kyung Hoe; Yi, Won Jin; Heo, Min Suk; Lee, Sam Sun; Choi, Soon Chul [Dept. of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    2014-12-15

    Postoperative maxillary cysts are locally aggressive lesions, usually developing as delayed complications many years after radical antral surgery. This report describes a case of bilateral postoperative maxillary cysts following orthognathic surgery performed approximately 21 years previously. The patient complained of stinging pain on her right cheek. Radiographic examination revealed low-attenuation lesions on both maxillary sinuses with discontinuously corticated margins without distinct expansion or bone destruction. The cysts were enucleated with the removal of metal plates and screws for pain relief. Histopathological examination confirmed the diagnosis of postoperative maxillary cysts lined by ciliated, pseudostratified columnar cells. The patient has remained asymptomatic thus far, and there was no evidence of local recurrence at 21 months of postoperative follow-up.

  7. Simplified Model Surgery Technique for Segmental Maxillary Surgeries

    Directory of Open Access Journals (Sweden)

    Namit Nagar

    2011-01-01

    Full Text Available Model surgery is the dental cast version of cephalometric prediction of surgical results. Patients having vertical maxillary excess with prognathism invariably require Lefort I osteotomy with maxillary segmentation and maxillary first premolar extractions during surgery. Traditionally, model surgeries in these cases have been done by sawing the model through the first premolar interproximal area and removing that segment. This clinical innovation employed the use of X-ray film strips as separators in maxillary first premolar interproximal area. The method advocated is a time-saving procedure where no special clinical or laboratory tools, such as plaster saw (with accompanying plaster dust, were required and reusable separators were made from old and discarded X-ray films.

  8. Rapid analysis of pyrethroid insecticides in aquaculture seawater samples via membrane-assisted solvent extraction coupled with gas chromatography-electron capture detection

    OpenAIRE

    Shi, X.Z.; Song, S.Q.; Sun, A.L.; Liu, J.H.; Li, D.X.; Chen, J.

    2012-01-01

    A simple, efficient, and environmentally friendly membrane-assisted solvent extraction (MASE) method for the extraction and preconcentration of six pyrethroid insecticides from aquaculture seawater samples followed by gas chromatography-electron capture detection (GC-ECD) was successfully proposed. The operating conditions for MASE, such as the extraction solvent, solvent volume, NaCl concentration, stirring rate, extraction time, and temperature, were optimized. Compared to conventional Flor...

  9. Bi-rooted Primary Maxillary Canines: A Case Report

    Directory of Open Access Journals (Sweden)

    Maryam Talebi

    2010-09-01

    Full Text Available This report presents a rare case of bi-rooted primary maxillary canines. A 6-year-old girl presented at the Department of Pediatric Dentistry, Faculty of Dentistry, Mashhad University of Medical Sciences, Iran, with the chief complaint of pain in the lower right quadrant of her dentition. Radiographic examination revealed bifurcation of primary maxillary canine roots. This report discusses the possible etiology of bi-rooted canines, implications for the developing dentition, and treatment options for these teeth.

  10. Orthopedic Treatment of Maxillary Expansion: A Review of the Literature

    OpenAIRE

    Sylvia Ng; Minjie Li; Yanqi Yang

    2015-01-01

    Transverse maxillary deficiency, no matter in adolescents or in adults, is frequently seen in the patients seeking orthodontic treatment. The treatment goal of detaching the midpalatal suture can be achieved using an expansion device. In present article we give a review on various palatal expansion appliances and treatment protocol. A comprehensive search of the literatures was performed to observe the regime of different maxillary expansion appliances and therapies.

  11. Unusal canal configuration in maxillary and mandibular second molars

    Directory of Open Access Journals (Sweden)

    Ramachandran Ragunathan

    2016-01-01

    Full Text Available This clinical article describes three different case reports of maxillary and mandibular second molars with the unusual anatomy of single root with a single canal and their endodontic management. An unusual case of bilateralism is observed in the first two cases in the form of single-rooted second mandibular molars in both the quadrant of the same patient. The presence of maxillary second molar with single root and single canal in the third case is unusual.

  12. Closing a Large Maxillary Median Diastema using Bapat Power Arm

    OpenAIRE

    M Bapat, Shirish; Singh, Chanchal; Bandejiya, Prashant

    2017-01-01

    Aim The aim of this study is to present a case of large maxillary median diastema closed by bodily movement of central incisors using Bapat power arm (BPA). Materials and methods After extraction of mesiodens, a power chain with a force of 120 gm was applied to BPA ligated to preadjusted edgewise brackets bonded to maxillary central incisors to move them over round steel wire for closure of resultant diastema. Bonded retainer was placed after the closure of median diastema. Results The median...

  13. The radiographic localization of unerupted maxillary incisors and supernumeraries

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Duk; Lee, Chang Yul; You, Choong Hyun [Chosun University College of Medicine, Kwangju (Korea, Republic of)

    2003-12-15

    To evaluate the use of the vertical tube shift from a panoramic film and a periapical film to localize unerupted maxillary incisors and supernumeraries. The total of 103 displaced maxillary incisors or embedded supernumeraries were examined in this study. The vertical tube shift technique with panoramic and periapical radiography by normal projection taken and compared to localize the position of the embedded maxillary incisors or supernumeraries by a radiologist and 5 general dentists. The gold standard used for the radiographic comparisons was the true position of the embedded tooth as confirmed by horizontal tube shift technique using three periapical radiographs. The general dentist examiners were instructed on the use of the modified acronym 'SLDOBU' by the radiologist as it pertains to panoramic radiographs as the principle of vertical tube shift. All of the embedded maxillary incisors and supernumeraries were successfully located using the vertical tube shift from a panoramic and a maxillary anterior periapical radiograph by the radiologist and 5 general dentists. The use of a panoramic film with a periapical film combination for a vertical tube shift can be useful to localize unerupted maxillary incisors and supernumeraries.

  14. Jagged1 is essential for osteoblast development during maxillary ossification

    Science.gov (United States)

    Hill, Cynthia R.; Yuasa, Masato; Schoenecker, Jonathan; Goudy, Steven L.

    2015-01-01

    Maxillary hypoplasia occurs due to insufficient maxillary intramembranous ossification, leading to poor dental occlusion, respiratory obstruction and cosmetic deformities. Conditional deletion of Jagged1 (Jag1) in cranial neural crest (CNC) cells using Wnt1-cre; Jagged1f/f (Jag1CKO) led to maxillary hypoplasia characterized by intrinsic differences in bone morphology and density using μCT evaluation. Jag1CKO maxillas had altered collagen deposition, delayed ossification, and reduced expression of early and late determinants of osteoblast development during maxillary ossification. In vitro bone cultures on Jag1CKO mouse embryonic maxillary mesenchymal (MEMM) cells demonstrated decreased mineralization that was also associated with diminished induction of osteoblast determinants. BMP receptor expression was dysregulated in the Jag1CKO MEMM cells suggesting that these cells were unable to respond to BMP-induced differentiation. JAG1-Fc rescued in vitro mineralization and osteoblast gene expression changes. These data suggest that JAG1 signaling in CNC-derived MEMM cells is required for osteoblast development and differentiation during maxillary ossification. PMID:24491691

  15. Jagged1 is essential for osteoblast development during maxillary ossification.

    Science.gov (United States)

    Hill, Cynthia R; Yuasa, Masato; Schoenecker, Jonathan; Goudy, Steven L

    2014-05-01

    Maxillary hypoplasia occurs due to insufficient maxillary intramembranous ossification, leading to poor dental occlusion, respiratory obstruction and cosmetic deformities. Conditional deletion of Jagged1 (Jag1) in cranial neural crest (CNC) cells using Wnt1-cre; Jagged1(f/f) (Jag1CKO) led to maxillary hypoplasia characterized by intrinsic differences in bone morphology and density using μCT evaluation. Jag1CKO maxillas revealed altered collagen deposition, delayed ossification, and reduced expression of early and late determinants of osteoblast development during maxillary ossification. In vitro bone cultures on Jag1CKO mouse embryonic maxillary mesenchymal (MEMM) cells demonstrated decreased mineralization that was also associated with diminished induction of osteoblast determinants. BMP receptor expression was dysregulated in the Jag1CKO MEMM cells suggesting that these cells were unable to respond to BMP-induced differentiation. JAG1-Fc rescued in vitro mineralization and osteoblast gene expression changes. These data suggest that JAG1 signaling in CNC-derived MEMM cells is required for osteoblast development and differentiation during maxillary ossification. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  16. Differential protein expression in the secretory fluids of maxillary sinusitis and maxillary retention cyst.

    Science.gov (United States)

    Kim, Soung Min; Eo, Mi Young; Cho, Yun Ju; Kim, Yeon Sook; Lee, Suk Keun

    2017-01-01

    Both maxillary sinusitis (MS) and maxillary retention cyst (MRC) involve the maxillary sinus and show similar clinical features. Clinically, differentiating between MS and MRC is sometimes difficult in asymptomatic patients, despite their quite different pathogenic behaviors. To identify differential protein expressions in the secretory fluids of MS and MRC, 25 cases of asymptomatic MS and 15 cases of asymptomatic MRC were examined pathologically in this study. All patients underwent routine endoscopic sinus surgery or modified Caldwell-Luc procedure and the sinus mucosal specimens obtained during these procedures with the approval of the Institutional Review Board. Their secretory fluids were analyzed via immunoprecipitation-based high-performance liquid chromatography (IP-HPLC) using 25 types of antiserum, including inflammatory cytokines, antimicrobial proteins, and mucosal protective proteins. In the histological examinations, MS and MRC showed similar features in the secretory columnar epithelial lining and thick submucosal connective tissue, both of which contained few inflammatory cells infiltrates. The IP-HPLC analysis revealed that TNFα, IL-1, -8, MMP-3, -10, α1-antitrypsin, cathepsin C, lysozyme, lactoferrin, β-defensin-1, -3, LL-37, mucocidin, and mucin-1 were more intensely expressed in MS than in MRC; whereas IgA, cystatin A, and proline-rich proteins were more strongly expressed in MRC than in MS. These data indicate that the secretory fluid of MS is indicative of a more robust inflammatory reaction to certain bacteria compared to that of MRC, while the secretory fluid of MRC contains more abundant mucosal protective proteins compared to that of MS. Taken together, the IP-HPLC analysis of MS and MRC secretory fluid revealed that MRC showed a weaker inflammatory reaction but a stronger mucosal protective function than MS.

  17. Microwave assisted chemistry: A rapid and regioselective route for direct ortho-acylation of phenols and naphthols by methanesulfonic acid as catalyst

    Directory of Open Access Journals (Sweden)

    Hossein Naeimi

    2017-05-01

    Full Text Available Direct ortho-acylation of phenols and naphthols with methanesulfonic acid (MSA as the catalyst has been studied under microwave stimulation. The microwave assisted reaction was environmentally benign in terms of faster reaction, useful conditions and higher yield of the desired products. However, after 3–4 min reaction time at 200–300 Watt, selectivity to over 98% ortho-acylation products was obtained. These reactions have some advantages in competition with other methods such as; short reaction times, high yield and regioselectivity of products, mild reaction conditions and easy workup of the reactions.

  18. Rapid identification of positive blood cultures by matrix-assisted laser desorption ionization-time of flight mass spectrometry using prewarmed agar plates.

    Science.gov (United States)

    Bhatti, M M; Boonlayangoor, S; Beavis, K G; Tesic, V

    2014-12-01

    This study describes an inexpensive and straightforward method for identifying bacteria by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) directly from positive blood cultures using prewarmed agar plates. Different inoculation methods and incubation times were evaluated to determine the optimal conditions. The two methods using pelleted material from positive culture bottles performed best. In particular, the pellet streak method correctly identified 94% of the Gram negatives following 4 h of incubation and 98% of the Gram positives following 6 h of incubation. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  19. Comparative assessment of maxillary canine index and maxillary first molar dimensions for sex determination in forensic odontology.

    Science.gov (United States)

    Phulari, Rashmi G S; Rathore, Rajendrasinh; Talegaon, Trupti; Jariwala, Prachi

    2017-01-01

    Sexual identification of immature skeletal remains is still a difficult problem to solve in forensic anthropology. In such situations, the odontometric features of the teeth can be of immense help. Teeth, being the hardest and chemically the most stable tissue in the body, are an excellent material in living and nonliving populations for anthropological, genetic, odontologic, and forensic investigations. Using tooth size standards, whenever it is possible to predict the sex, identification is made easier because then only missing persons of one sex need to be considered. To determine sex from the odontometric data using maxillary canine index and maxillary first molar dimensions and to determine which index gives higher accuracy rate for sex determination using only maxillary cast. In a sample size of 200 population (100 male and 100 female), alginate impression was taken of maxillary arch and poured with dental stone. Using Vernier caliper, the dimension of maxillary first molar (buccolingual [BL] and mesiodistal [MD]), canine (MD), and intercanine distance was measured on the cast. The obtained data were analyzed using discriminant statistical analysis. This study concludes that BL dimension of maxillary first molar is a more reliable indicator for gender determination than other molar and canine dimensions in maxilla.

  20. Influence of maxillary posterior dentoalveolar discrepancy on angulation of maxillary molars in individuals with skeletal open bite.

    Science.gov (United States)

    Arriola-Guillén, Luis Ernesto; Aliaga-Del Castillo, Aron; Flores-Mir, Carlos

    2016-12-01

    The aim of this study was to determine the effect of the maxillary posterior dentoalveolar discrepancy (MPDD) on the angulation of maxillary molars in open bite subjects. Pre-treatment lateral cephalograms of 90 young adults with skeletal open bite were examined. The sample initially included six groups categorized according to MPDD condition (present or absent) and sagittal skeletal facial growth patterns (classes I, II, or III). Then, the sample was separated into two groups according to MPDD (present = 50, absent = 40). When the eruption of the maxillary third molar was apparently blocked by the presence of an erupted second molar, a MPDD was considered. Maxillary molar angulation was measured. Independent T test was performed to determine differences between the groups considering MPDD condition. Principal component analysis (PCA) and multivariate analysis (MANCOVA) test were also developed. A decreased molar angulation was found in all groups with MPDD (overall p MANCOVA test was applied. Significance was only found for MPDD (p < 0.001), APDI (p = 0.001), and ratio (A'6'/A'P') (p = 0.026) for maxillary first molar angulation and APDI (p = 0.011) and MPDD (p < 0.001) for maxillary second molar angulation. The MPDD generates a major mesial displacement of the second and first molar roots with a concurrent simultaneous distal angulation of the associated crowns in individuals with skeletal open bite.

  1. Rapid crystallization of WS{sub 2} films assisted by a thin nickel layer: An in situ energy-dispersive X-ray diffraction study

    Energy Technology Data Exchange (ETDEWEB)

    Ellmer, K.; Seeger, S. [Hahn-Meitner-Institut Berlin, Dept. Solare Energetik, Glienicker Str. 100, 14109 Berlin (Germany); Mientus, R. [Opto-Transmitter-Umweltschutz-Technologie e.V., Koepenicker Str. 325b, 12555 Berlin (Germany)

    2006-08-15

    By rapid thermal crystallization of an amorphous WS{sub 3+x} film, deposited by reactive magnetron sputtering at temperatures below 150 C, layer-type semiconducting tungsten disulfide films (WS{sub 2}) were grown. The rapid crystallization was monitored in real-time by in situ energy-dispersive X-ray diffraction. The films crystallize very fast (>40 nm/s), provided that a thin nickel film acts as nucleation seeds. Experiments on different substrates and the onset of the crystallization only at a temperature between 600 and 700 C points to the decisive role of seeds for the textured growth of WS{sub 2}, most probably liquid NiS{sub x} drops. The rapidly crystallized WS{sub 2} films exhibit a pronounced (001) texture with the van der Waals planes oriented parallel to the surface, leading to photoactive layers with a high hole mobility of about 80 cm{sup 2}/Vs making such films suitable as absorbers for thin film solar cells. (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  2. Morphological variation of the maxillary lateral incisor

    Directory of Open Access Journals (Sweden)

    Shintaro Kondo

    2014-11-01

    Full Text Available The maxillary lateral incisor is a variable tooth morphologically. This tooth frequently shows reduction in size, and also various alterations in shape, for example, peg-shaped, cone-shaped, barrel-shaped and canine-shaped. The lateral incisor variant can be analyzed by family studies and using twin models, and these approaches have shown that genetic, epigenetic and environmental factors can all contribute to variation in the trait. Discordance of the phenotype in monozygotic twin pairs could be explained by the following two hypotheses: (1 the embryological environment of monochorionic twin pairs who share the same placenta and chorionic membrane during the prenatal period may differ, (2 phenotypic variation may be caused by epigenetic influences. Possible developmental factors are discussed in this review. Recent studies suggest that Msx1, Pax9 and Axin2 genes predispose to lateral incisor agenesis. Tooth reduction and agenesis seem to represent inter-related complex multifactorial traits, influenced by a combination of gene expression and function, environmental interaction and developing timing. Thus, accumulation of large data banks of morphological data is needed to support and clarify ongoing molecular genetic studies of dental development.

  3. [Maxillary sinusitis of odontogenic origin: surgical treatment].

    Science.gov (United States)

    Chemli, H; Mnejja, M; Dhouib, M; Karray, F; Ghorbel, A; Abdelmoula, M

    2012-04-01

    The frequency of maxillary sinusitis of dental origin (MSDO) is under estimated. The medical and surgical treatment has improved thanks to endoscopic guidance. We report our experience and strategy in the treatment of MSDO. Twenty-two patients presenting with MSDO were treated between 1998 and 2008. The results were evaluated on clinical, functional, sinusal, and odontologic signs. MSDO accounted for 16% of surgically managed sinusitis. CT was performed in 95% of cases. The etiologies were apical leakage in seven patients, migration of a tooth or root during extraction, or presence of ectopic tooth in the sinus in nine patients, a cyst in three patients, and oroantral communication in three patients. Surgery was performed after antibiotic and NSAID treatment. The first surgical step was the treatment of the odontogenic source. The second step was sinus drainage by endoscopic treatment in 64%, Caldwell-Luc in 23%, and drainage by oroantral communication enlarged then closed in the same operative time in 13%. The follow up ranged from 3 months to 10 years. Early postoperative superinfection was observed in two patients. Two patients presented with recurrent sinusitis. The postoperative sequels were hyposmia in three patients, dental pulpotomy, and trigeminal neuralgia in five patients treated by Caldwell-Luc surgery. Nasal endoscopy has improved the surgical management of MSDO. It makes curettage and exclusion of sinus cavities obsolete. It is reliable and has a low rate of complications. The best treatment remains prevention. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  4. A Radiologic Study of the Relationship of the Maxillary Sinus Floor and Apex of the Maxillary Molar

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Hae Rym; Park, Chang Seo [Dept. of Dental Radiology, College of Dentistry, Yonsei University, Seoul (Korea, Republic of)

    1998-02-15

    In this study, radiographic evaluation was made using panoramic radiography and cross-sectional tomography of SCANORA in male and female adults in their 20 s on the relationship between the maxillary sinus floor and the apex of the maxillary molar, to test the accuracy and effectiveness of the cross-sectional tomography, and to use this information in the assessment of preop, and postop, root canal treatment, apical surgery, extraction and implantology. Forty-one adults with an average age of 24.4 years were studied panoramic radiography and cross-sectional tomography. In panoramic view and cross-sectional view, the position of the apices of maxillary molars were classified as separated, contacted, or protruded type; the general shape of the maxillary sinus floor was evaluated horizontally and vertically from cross-sectional tomography. The accuracy of each radiography was tested using maxilla from 5 fresh cadavers from the Anatomy Lab at Yonsei University Dental College, and panoramic view and cross-sectional tomography were taken in the same condition as with the patients. The results were as follows: 1. Panoramic view and cross-sectional view were taken in the maxilla specimen, and the actual distance between the maxillary sinus floor and the tooth apices were measured in the specimen; the median values of the distance from the tooth apices to the maxillary sinus floor in the panoramic view, cross-sectional view and in the accrual maxilla specimen were 2.83 mm, 4.51 mm, and 4.15 mm, respectively. In the cross-sectional view, the measured distance was close to the actual distance but in the panoramic view, the measured distance was far from the actual distance. 2. When the results of the panoramic view and cross-sectional view were compared, 40.5% of the results agreed with each other in the two radiographic methods and buccal roots of the 2nd molar were the closest to the maxillary sinus floor in the cross-sectional tomography.3. In cross-sectional view, when

  5. Rapid microwave assisted synthesis of graphene nanosheets/polyethyleneimine/gold nanoparticle composite and its application to the selective electrochemical determination of dopamine.

    Science.gov (United States)

    Ponnusamy, Vinoth Kumar; Mani, Veerappan; Chen, Shen-Ming; Huang, Wan-Tran; Jen, Jen-Fon

    2014-03-01

    In this study, a simple and fast microwave assisted chemical reduction method for the preparation of graphene nanosheet/polyethyleneimine/gold nanoparticle (GNS/PEI/AuNP) composite was developed. PEI, a cationic polymer, was used both as a non-covalent functionalizing agent for the graphene oxide nanosheets (GONSs) through electrostatic interactions in the aqueous medium and also as a stabilizing agent for the formation of AuNPs on PEI wrapped GNSs. This preparation method involves a simple mixing step followed by a simultaneous microwave assisted chemical reduction of the GONSs and gold ions. The prepared composite exhibits the dispersion of high density AuNPs which were densely decorated on the large surface area of the PEI wrapped GNS. X-ray photoelectron spectroscopy, powder X-ray diffraction, high-resolution transmission electron microscopy, field-emission scanning electron microscopy with energy dispersive X-ray spectroscopy, and thermo-gravimetric analysis, were used to characterize the properties of the resultant composite. The prepared GNS/PEI/AuNP composite film exhibited excellent electrocatalytical activity towards the selective determination of dopamine in the presence of ascorbic acid, which showed potential application in electrochemical sensors. The applicability of the presented sensor was also demonstrated for the determination of dopamine in human urine samples. © 2013 Elsevier B.V. All rights reserved.

  6. Digital design of functional surgery for odontogenic cyst intruding into maxillary sinus.

    Science.gov (United States)

    Hu, Ying Kai; Yang, Chi; Xu, Guang Zhou; Xie, Qian Yang

    2017-03-19

    Traditional Caldwell-Luc approach needs modifications for odontogenic cysts intruding into the maxillary sinus, to preserve sinus mucosa and bony contour. Recently, digital technology has been widely applied to the field of maxillofacial surgery, guiding the surgical plan and improving its accuracy. This study attempted to present and evaluate the functional surgery of odontogenic cysts intruding into the maxillary sinus using a computer-assisted pre-surgical design. Consecutive patients with odontogenic cysts intruding into the posterior part of the maxillary sinus were enrolled. Method I "Bony wall reimplantation method" was performed for large lesions exceeding the zygomatic alveolar crest but without apparent bone destruction of the anterior wall of the sinus, while Method II "bone removal method" was more convenient for small lesions near to the zygomatic alveolar crest. The gap was filled with a pedicled Buccal Fat Pad (BFP) after lesion removal and all cases were without inferior meatal antrostomy. A total of 45 cases were included in the study. 22 were operated using method I while 23 were operated with method II. Operations were completed in 20min. Pain disappeared in 3.62 days on average, and swelling 6.47 days. Nasal bleeding occurred in 8 patients lasting 1-3 days. Suppurative inflammation was observed in 1 patient, and infection occurred after bone reposition. Other repositioned free bony wall was without resorption in CT images. Sinus mucosa and bony wall should be conserved. Preoperative digital design can guide osteotomy effectively during the surgery. Bone reposition is not suitable for suppurative inflammation. The pedicled BFP is enough for drainage and inferior meatal antrostomy is not necessary. Copyright © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  7. Interceptive orthopedics for the correction of maxillary transverse and sagittal deficiency in the early mixed dentition period

    Directory of Open Access Journals (Sweden)

    Ashok Kumar Talapaneni

    2011-01-01

    Full Text Available Dentofacial Orthopedics directed to a hypoplastic maxilla in the prepubertal period redirects growth of the maxilla in the vertical, transverse and sagittal planes of space. The orthopedic correction of maxillary hypoplasia in the early mixed dentition period thus intercepts the establishment of permanent structural asymmetry in the mandible and helps in the achievement of optimal dentofacial esthetics. This paper presents the growth redirection in a hypoplastic maxilla of an 8-year-old girl with simultaneous rapid maxillary expansion and protraction headgear therapy for a period of 11 months which corrected the posterior unilateral cross-bite, the positional asymmetry of the mandible and established an orthognathic profile in the individual.

  8. Rapid detection of meticillin-resistant Staphylococcus aureus bacteraemia using combined three-hour short-incubation matrix-assisted laser desorption/ionization time-of-flight MS identification and Alere Culture Colony PBP2a detection test.

    Science.gov (United States)

    Delport, Johannes Andries; Mohorovic, Ivor; Burn, Sandi; McCormick, John Kenneth; Schaus, David; Lannigan, Robert; John, Michael

    2016-07-01

    Meticillin-resistant Staphylococcus aureus (MRSA) bloodstream infection is responsible for significant morbidity, with mortality rates as high as 60 % if not treated appropriately. We describe a rapid method to detect MRSA in blood cultures using a combined three-hour short-incubation BRUKER matrix-assisted laser desorption/ionization time-of-flight MS BioTyper protocol and a qualitative immunochromatographic assay, the Alere Culture Colony Test PBP2a detection test. We compared this combined method with a molecular method detecting the nuc and mecA genes currently performed in our laboratory. One hundred and seventeen S. aureus blood cultures were tested of which 35 were MRSA and 82 were meticillin-sensitive S. aureus (MSSA). The rapid combined test correctly identified 100 % (82/82) of the MSSA and 85.7 % (30/35) of the MRSA after 3 h. There were five false negative results where the isolates were correctly identified as S. aureus, but PBP2a was not detected by the Culture Colony Test. The combined method has a sensitivity of 87.5 %, specificity of 100 %, a positive predictive value of 100 % and a negative predictive value of 94.3 % with the prevalence of MRSA in our S. aureus blood cultures. The combined rapid method offers a significant benefit to early detection of MRSA in positive blood cultures.

  9. Rapid detection of t(15;17)(q24;q21) in acute promyelocytic leukaemia by microwave-assisted fluorescence in situ hybridization.

    Science.gov (United States)

    Soriani, Silvia; Mura, Cinzia; Panico, Anna Rita; Scarpa, Anna Maria; Recchimuzzo, Patrizia; Dadati, Raffaella; Farioli, Renata; De Canal, Gabriella; Mura, Maria Angela; Cesana, Clara

    2017-03-01

    Acute promyelocytic leukaemia (APL) is a hematologic malignancy characterized by the rearrangement of the PML and RARα genes, mostly due to a reciprocal chromosomal translocation t(15;17)(q24;q21). A quick APL diagnosis is essential for starting a prompt suitable therapy. We describe a new rapid diagnostic laboratory approach to detect the PML-RARα rearrangement, which gives clear genetic results within 30 min of hybridization. It combines quick cell harvesting, fluorescence in situ hybridization performed with commercial DNA probe and microwave beams supplied by a domestic microwave oven. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Ultrasonic-assisted ultra-rapid synthesis of monodisperse meso-SiO2@Fe3O4 microspheres with enhanced mesoporous structure.

    Science.gov (United States)

    Liu, Hongfei; Ji, Shengfu; Yang, Hao; Zhang, Huan; Tang, Mi

    2014-03-01

    A core-shell-type of meso-SiO2@Fe3O4 microsphere was synthesized via an ultrasonic-assisted surfactant-templating process using solvothermal synthesized Fe3O4 as core, tetraethoxysilane (TEOS) as silica source, and cetyltrimethyl ammonium bromide (CTAB) as templates. The samples were characterized by FT-IR, XRD, TEM, N2 adsorption-desorption technology, and vibrating sample magnetometer (VSM). The results show that as-prepared meso-SiO2@Fe3O4(E) and meso-SiO2@Fe3O4(C) microspheres, treated by acetone extraction and high temperature calcination, respectively, still maintain uniform core-shell structure with desirable mesoporous silica shell. Therein, the meso-SiO2@Fe3O4(E) microspheres possess a distinct pore size distribution in 1.8-3.0 nm with large specific surface area (468.6 m(2)/g) and pore volume (0.35 cm(3)/g). Noteworthily, the coating period of this ultrasonic-assisted method (40 min) is much shorter than that of the conventional method (12-24 h). The morphology of microspheres and the mesoporous structure of silica shell are significantly influenced by initial concentration of CTAB (CCTAB), ultrasonic irradiation power (P) and ultrasonic irradiation time (t). The acceleration roles of ultrasonic irradiation take effect during the whole coating process of mesoporous silica shell, including hydrolysis-condensation process of TEOS, co-assembly of hydrolyzed precursors and CTAB, and deposition of silica oligomers. In addition, the use of ultrasonic irradiation is favorable for improving the homogeneity of silica shell and the monodispersity of meso-SiO2@Fe3O4 microspheres. Copyright © 2013. Published by Elsevier B.V.

  11. Matrix-assisted laser desorption/ionization mass spectrometric imaging for the rapid segmental analysis of methamphetamine in a single hair using umbelliferone as a matrix.

    Science.gov (United States)

    Wang, Hang; Wang, Ying

    2017-07-04

    Segmental hair analysis offers a longer period for retrospective drug detection than blood or urine. Hair is a keratinous fiber and is strongly hydrophobic. The embedding of drugs in hydrophobic hair at low concentrations makes it difficult for extraction and detection with matrix-assisted laser desorption/ionization (MALDI) coupled with mass spectrometric imaging (MSI). In this study, a single scalp hair was longitudinally cut with a cryostat section to a length of 4 mm and fixed onto a stainless steel MALDI plate. Umbelliferone was used as a new hydrophobic matrix to enrich and assist the ionization efficiency of methamphetamine in the hair sample. MALDI-Fourier transform ion cyclotron resonance (FTICR)-MS profiling and imaging were performed for direct detection and mapping of methamphetamine on the longitudinal sections of the single hair sample in positive ion mode. Using MALDI-MSI, the distribution of methamphetamine was observed throughout five longitudinally sectioned hair samples from a drug abuser. The changes of methamphetamine were also semi-quantified by comparing the ratios of methamphetamine/internal standard (I.S). This method improves the detection sensitivity of target drugs embedded in a hair matrix for imaging with mass spectrometry. The method could provide a detection level of methamphetamine down to a nanogram per milligram incorporated into hair. The results were also compared with the conventional high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS) method. Changes in the imaging results over time by the MSI method showed good semi-quantitative correlation to the results from the HPLC-MS/MS method. This study provides a powerful tool for drug abuse control and forensic medicine analysis in a narrow time frame, and a reduction in the sample amount required. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Rapid identification of Enterobacteriaceae in milk and dairy products with the Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS

    Directory of Open Access Journals (Sweden)

    Miroslava Kačániová

    2017-11-01

    Full Text Available Identification of microorganisms by MALDI-TOF MS Biotyper has been demonstrated to be accurate, rapid and lower cost than conventional food investigation methods. Rapid identification of pathogenic and spoilage microorganisms is crucial for dairy industry to ensure the quality and safety of milk and milk products. In this study, the bacterial species representing the Enterobacteriaceae family were identified in raw milk and milk products using the MALDI-TOF MS mass spectrometry. Altogether, 20 samples of Slovak milk and milk products were examined. Samples were cultured on VRBG agar at 37 °C for 24-48 h. Typical bacterial colonies were selected for identification with MALDI-TOF MS Biotyper. Escherichia coli and Enterobacter sp. were the most abundant  Enterobacteriaceae family representatives identified. E. coli was found in nine  and Enterobacter sp. in eight samples. Enterobacter sp. comprised 49 % and Escherichia coli 23 % of all bacterial isolates. The study shows that MALDI-TOF MS Biotyper was reliable identification method of Enterobacteriaceae in milk and dairy products. This method was helpful in evaluation of bacterial contamination of milk.

  13. Antibiotics for acute maxillary sinusitis in adults.

    Science.gov (United States)

    Ahovuo-Saloranta, Anneli; Rautakorpi, Ulla-Maija; Borisenko, Oleg V; Liira, Helena; Williams, John W; Mäkelä, Marjukka

    2014-02-11

    Sinusitis is one of the most common diagnoses among adults in ambulatory care, accounting for 15% to 21% of all adult outpatient antibiotic prescriptions. However, the role of antibiotics for sinusitis is controversial. To assess the effects of antibiotics in adults with acute maxillary sinusitis by comparing antibiotics with placebo, antibiotics from different classes and the side effects of different treatments. We searched CENTRAL 2013, Issue 2, MEDLINE (1946 to March week 3, 2013), EMBASE (1974 to March 2013), SIGLE (OpenSIGLE, later OpenGrey (accessed 15 January 2013)), reference lists of the identified trials and systematic reviews of placebo-controlled studies. We also searched for ongoing trials via ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform (ICTRP). We imposed no language or publication restrictions. Randomised controlled trials (RCTs) comparing antibiotics with placebo or antibiotics from different classes for acute maxillary sinusitis in adults. We included trials with clinically diagnosed acute sinusitis, confirmed or not by imaging or bacterial culture. Two review authors independently screened search results, extracted data and assessed trial quality. We calculated risk ratios (RRs) for differences between intervention and control groups in whether the treatment failed or not. All measures are presented with 95% confidence intervals (CIs). We conducted the meta-analyses using either the fixed-effect or random-effects model. In meta-analyses of the placebo-controlled studies, we combined data across antibiotic classes. Primary outcomes were clinical failure rates at 7 to 15 days and 16 to 60 days follow-up. We used GRADEpro to assess the quality of the evidence. We included 63 studies in this updated review; nine placebo-controlled studies involving 1915 participants (seven of the studies clearly conducted in primary care settings) and 54 studies comparing different classes of antibiotics (10 different comparisons

  14. Avaliação cefalométrica radiográfica da posição craniocervical de pacientes orientados em posição natural da cabeça pré e pós-expansão rápida da maxila Cephalometric radiographic evaluation of the craniocervical position of patients oriented in natural head position before and after the rapid maxillary expansion

    Directory of Open Access Journals (Sweden)

    Belini Augusto Villalba Freire-Maia

    2005-04-01

    Full Text Available O objetivo deste estudo foi avaliar a eventual alteração na posição craniocervical de pacientes orientados na Posição Natural da Cabeça (PNC, após o procedimento de expansão rápida da maxila (ERM. Utilizaram-se telerradiografias em norma lateral, selecionadas do acervo de documentação da Clínica de Ortodontia Preventiva da Faculdade de Odontologia da Universidade de São Paulo, de 20 pacientes, com idades entre 5 a 11 anos (média de 9,0 anos, sendo 7 do gênero masculino e 13 do feminino, obtidas no início do tratamento e imediatamente após a fase ativa da expansão da maxila. Os pacientes eram portadores de atresia da maxila e foram tratados com aparelho disjuntor tipo Biederman modificado. A partir dos cefalogramas pré e pós-ERM foram obtidas as grandezas angulares craniovertical (SN.VER, craniocervical (OPT.SN e CVT.SN, cervicohorizontal (OPT.HOR, CVT.HOR e o ângulo da curvatura cervical (OPT.CVT. Após análise estatística e interpretação dos resultados obtidos concluímos que a posição da cabeça não apresentou alteração estatisticamente significativa. Não foram observadas diferenças estatisticamente significativas entre os gêneros quando comparadas as fases pré e pós-ERM para as grandezas estudadas. O método de obtenção de telerradiografias laterais em Orientação Natural da Cabeça mostrou-se confiável e reproduzível na amostra estudada, mesmo na presença de intervenção ortodôntica-ortopédica entre as séries de radiografias.The aim of this study was to evaluate the eventual alteration in the craniocervical position of patients, oriented in the Natural Head Position (NHP, after the rapid maxillary expansion (RME procedure. We have used lateral radiographs, selected from the documentation file of the Preventive Orthodontics Clinic, School of Dentistry, University of São Paulo. Our sample consisted of 20 patients (7M:13F, with ages ranging from 5.08 up to 11.08 years (mean of 9,0. The

  15. Light weight hollow maxillary complete denture: A case series

    Directory of Open Access Journals (Sweden)

    Laxman Singh Kaira

    2012-01-01

    Full Text Available Retention, stability and support are the basic principles on which the success of a complete denture relies on. The skill lies in applying these principles efficiently in critical situations. Residual ridge resorption occurs at a three times faster rate in mandibular arch than in the maxillary arch. The severely resorbed maxillary and mandibular edentulous arches that are narrow and constricted with increased interarch space provide decreased support, retention and stability. The consequent weight of the processed complete denture only compromises them further. The severely resorbed jaw can have various treatment options. Extreme resorption of the maxillary denture-bearing area may lead to problems with prosthetic rehabilitation. The advantage of a hollow maxillary or mandibular denture is the reduction of excessive weight of acrylic resin, which normally replaces lost alveolar ridge in the interridge space of the denture wearer. This clinical report describes two case reports of edentulous patients with resorbed ridges where a simplified technique of fabricating a light weight hollow maxillary complete denture was used for the preservation of denture bearing areas.

  16. Posterior Open Bite Due to Failure of Maxillary Molar Eruption.

    Science.gov (United States)

    Yasumura, Toshihiko; Sueishi, Kenji

    2016-01-01

    Posterior open bite can cause problems with occlusion. It arises from systemic or local factors such as physical or functional interference, ankylosis, and failure of eruption. Primary failure of eruption (PFE) is a rare condition that is difficult to differentiate from ankylosis and requires complex treatment strategies. Here we report a 12-year-old girl who was referred to our hospital by her dentist for re-evaluation of eruption failure of the left maxillary secondary premolar and first and second molars with congenitally missing maxillary lateral teeth. The maxillary first molar was extracted for a therapeutic diagnosis. The left maxillary secondary premolar and second molar reacted well to subsequent orthodontic treatment. Auto-transplantation of the mandibular premolar to the maxil-lary arch was carried out to achieve optimal overjet, overbite, and occlusion. The active treatment period spanned 4 years and 1 month. Assessment of the patient's medical and dental history, prior trauma, and clinical conditions resulted in a therapeutic diagnosis of PFE. Satisfactory orthodontic treatment results were achieved.

  17. Coincidence of mandibular fractures with isolated posterior maxillary sinus fractures.

    Science.gov (United States)

    Blatt, Sebastian; Rahimi-Nedjat, Roman; Sagheb, Keyvan; Piechowiak, Lisa; Walter, Christian; Brüllmann, Dan

    2017-10-01

    There are no data available to show whether there is a relationship between mandibular fractures and isolated fractures of the posterior and/or lateral walls of the maxillary sinus. The aim of this study was to determine whether there is a coincidence between these fracture patterns. Four hundred large volume cone beam computed tomography scans (CBCT) of patients with a fracture of the mandible between 2008 and 2013 were analyzed retrospectively. Patients with multiple midfacial fractures were excluded. The radiographic findings were correlated with epidemiological and clinical data of the patients such as gender, age, treatment methods, or complications. The most frequent fracture sites of the mandible were the jaw angle, the parasymphysis region, and the condyle. Nineteen of the 400 patients (4.75%) had an isolated fracture of the lateral and/or posterior maxillary sinus. Odds-ratio analysis revealed a high tendency for significant correlation of condylar process fractures with isolated maxillary sinus fractures. Chi-square test demonstrated a P-value near statistical significance (P=.054). No other fracture site of the mandible could be associated with an isolated fracture of the maxillary sinus. A condylar process fracture of the mandible after trauma without any further injury of the midface may be associated with an isolated fracture of the lateral and/or posterior maxillary sinus. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Biochemical and Clinical Assessments of Segmental Maxillary Posterior Tooth Intrusion

    Directory of Open Access Journals (Sweden)

    Jintana Tasanapanont

    2017-01-01

    Full Text Available Objective. To compare chondroitin sulphate (CS levels around maxillary second premolars, first molars, and second molars between the unloaded and the loaded periods and to measure the rates of intrusion of maxillary posterior teeth during segmental posterior tooth intrusion. Materials and Methods. In this prospective clinical study, 105 teeth (from 15 patients exhibiting anterior open bite and requiring maxillary posterior tooth intrusion were studied. Competitive ELISA was used to detect CS levels. Dental casts (during the unloaded and loaded periods were scanned, and posterior tooth intrusion distances were measured. Results. During the unloaded period, the median CS levels around maxillary second premolars, first molars, second molars (experimental teeth, and mandibular first molars (negative control were 0.006, 0.055, 0.056, and 0.012 and during the loaded period were 2.592, 5.738, 4.727, and 0.163 ng/μg of total protein, respectively. The median CS levels around experimental teeth were significantly elevated during the loaded period. The mean rates of maxillary second premolar and first and second molar intrusion were 0.72, 0.58, and 0.40 mm/12 weeks, respectively. Conclusions. Biochemical and clinical assessments suggested that the segmental posterior tooth intrusion treatment modality with 50 g of vertical force per side was sufficient. Trial Registration. The study is registered as TCTR20170206006.

  19. Biochemical and Clinical Assessments of Segmental Maxillary Posterior Tooth Intrusion.

    Science.gov (United States)

    Tasanapanont, Jintana; Wattanachai, Tanapan; Apisariyakul, Janya; Pothacharoen, Peraphan; Ongchai, Siriwan; Kongtawelert, Prachya; Midtbø, Marit; Jotikasthira, Dhirawat

    2017-01-01

    Objective. To compare chondroitin sulphate (CS) levels around maxillary second premolars, first molars, and second molars between the unloaded and the loaded periods and to measure the rates of intrusion of maxillary posterior teeth during segmental posterior tooth intrusion. Materials and Methods. In this prospective clinical study, 105 teeth (from 15 patients exhibiting anterior open bite and requiring maxillary posterior tooth intrusion) were studied. Competitive ELISA was used to detect CS levels. Dental casts (during the unloaded and loaded periods) were scanned, and posterior tooth intrusion distances were measured. Results. During the unloaded period, the median CS levels around maxillary second premolars, first molars, second molars (experimental teeth), and mandibular first molars (negative control) were 0.006, 0.055, 0.056, and 0.012 and during the loaded period were 2.592, 5.738, 4.727, and 0.163 ng/μg of total protein, respectively. The median CS levels around experimental teeth were significantly elevated during the loaded period. The mean rates of maxillary second premolar and first and second molar intrusion were 0.72, 0.58, and 0.40 mm/12 weeks, respectively. Conclusions. Biochemical and clinical assessments suggested that the segmental posterior tooth intrusion treatment modality with 50 g of vertical force per side was sufficient. Trial Registration. The study is registered as TCTR20170206006.

  20. Unilateral maxillary molar distalization with zygoma-gear appliance.

    Science.gov (United States)

    Kilkis, Dogan; Bayram, Mehmet; Celikoglu, Mevlut; Nur, Metin

    2012-08-01

    The aim of this study was to present the orthodontic treatment of a 15-year-old boy with a unilateral maxillary molar distalization system, called the zygoma-gear appliance. It consisted of a zygomatic anchorage miniplate, an inner bow, and a Sentalloy closed coil spring (GAC International, Bohemia, NY). A distalizing force of 350 g was used during the distalization period. The unilateral Class II malocclusion was corrected in 5 months with the zygoma-gear appliance. The maxillary left first molar showed distalization of 4 mm with an inclination of 3°. The maxillary premolars moved distally with the help of the transseptal fibers. In addition, there were slight decreases in overjet (-0.5 mm) and maxillary incisor inclination (-1°), indicating no anchorage loss from the zygoma-gear appliance. Preadjusted fixed appliances (0.022 × 0.028-in, MBT system; 3M Unitek, Monrovia, Calif) were placed in both arches to achieve leveling and alignment. After 14 months of unilateral distalization with the zygoma-gear appliance and fixed appliances, Class I molar and canine relationships were established with satisfactory interdigitation of the posterior teeth. Acceptable overjet and overbite were also achieved. This article shows that this new system, the zygoma-gear appliance, can be used for unilateral maxillary molar distalization without anchorage loss. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  1. Assessment of the relationship between the maxillary molars and adjacent structures using cone beam computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Yun Hoa; Cho, Bong Hae [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Pusan National University, Yangsan (Korea, Republic of)

    2012-09-15

    This study investigated the relationship between the roots of the maxillary molars and the maxillary sinus using cone beam computed tomography (CBCT), and measured the distances between the roots of the maxillary molars and the sinus floor as well as the thickness of the bone between the root and the alveolar cortical plate. The study sample consisted of 83 patients with normally erupted bilateral maxillary first and second molars. A total of 332 maxillary molars were examined using CBCT images. The vertical relationship of each root with the maxillary sinus was classified into four types on CBCT cross-sectional images. The distance between the sinus floor and root and the bone thickness between the root and alveolar cortical plate were measured. In the buccal roots of the maxillary molars, a root protruding into the sinus occurred most frequently. A root projecting laterally along the sinus cavity was most common in the palatal roots of the maxillary first molars. The mesiobuccal roots of the maxillary second molar were closest to the sinus. The mesiobuccal roots of the first molars were closest to the cortical plate. The relationship between the roots of the maxillary molars and the sinus differed between the buccal and palatal roots. A root protruding into the sinus occurred more frequent in the buccal roots of the maxillary molars. The mesiobuccal root of the maxillary second molar was closest to the maxillary sinus floor and farthest from the alveolar cortical plate.

  2. Collagen-embedded hydroxylapatite-beta-tricalcium phosphate-silicon dioxide bone substitute granules assist rapid vascularization and promote cell growth

    Energy Technology Data Exchange (ETDEWEB)

    Ghanaati, Shahram M; Thimm, Benjamin W; Unger, Ronald E; Orth, Carina; Barbeck, Mike; Kirkpatrick, C James [Institute of Pathology, Johannes Gutenberg-University Mainz, Langenbeckstr.1, 55101 Mainz (Germany); Kohler, Thomas; Mueller, Ralph, E-mail: ghanaati@uni-mainz.d [Institute for Biomechanics, ETH Zuerich, Wolfgang-Pauli-Str.10, 8093 Zuerich (Switzerland)

    2010-04-15

    In the present study we assessed the biocompatibility in vitro and in vivo of a low-temperature sol-gel-manufactured SiO{sub 2}-based bone graft substitute. Human primary osteoblasts and the osteoblastic cell line, MG63, cultured on the SiO{sub 2} biomatrix in monoculture retained their osteoblastic morphology and cellular functionality in vitro. The effect of the biomaterial in vivo and its vascularization potential was tested subcutaneously in Wistar rats and demonstrated both rapid vascularization and good integration within the peri-implant tissue. Scaffold degradation was progressive during the first month after implantation, with tartrate-resistant acid phosphatase-positive macrophages being present and promoting scaffold degradation from an early stage. This manuscript describes successful osteoblastic growth promotion in vitro and a promising biomaterial integration and vasculogenesis in vivo for a possible therapeutic application of this biomatrix in future clinical studies.

  3. Bacterial rapid identification with matrix assisted laser desorption/ionization time-of-flight mass spectrometry: development of an 'in-house method' and comparison with Bruker Sepsityper(®) kit.

    Science.gov (United States)

    Frédéric Ric, S; Antoine, M; Bodson, A; Lissoir, B

    2015-10-01

    The objective of this study was to compare an in-house matrix-assisted laser desorption ionization with time of flight (MALDI-TOF) method and a commercial MALDI-TOF kit (Sepsityper(®) kit) for direct bacterial identification in positive blood cultures. We also evaluated the time saved and the cost associated with the rapid identification techniques. We used the BACTEC(®) automated system for detecting positive blood cultures. Direct identification using Sepsityper kit and the in-house method were compared with conventional identification by MALDI-TOF using pure bacterial culture on the solid phase. We also evaluated different cut-off scores for rapid bacterial identification. In total, 127 positive blood vials were selected. The rate of rapid identification with the MALDI Sepsityper kit was 25.2% with the standard cut-off and 33.9% with the enlarged cut-off, while the results for the in-house method were 44.1 and 61.4%, respectively. Error rates with the enlarged cut-off were 6.98 (n = 3) and 2.56% (n = 2) for Sepsityper and the in-house method, respectively. Identification rates were higher for gram-negative bacteria. Direct bacterial identification succeeded in supplying rapid identification of the causative organism in cases of sepsis. The time taken to obtain a result was nearly 24  hours shorter for the direct bacterial identification methods than for conventional MALDI-TOF on solid phase culture. Compared with the Sepsityper kit, the in-house method offered better results and fewer errors, was more cost-effective and easier to use.

  4. PERFORATION OF INFERIOR ALVEOLAR NERVE BY MAXILLARY ARTERY. Perforation of inferior alveolar nerve by maxillary artery

    Directory of Open Access Journals (Sweden)

    Prakash B Billakanti

    2016-03-01

    Full Text Available La fosa infratemporal es un área anatómica clínicamente importante para la administración de agentes anestésicos locales en odontología y cirugía maxilofacial. Fueron estudiadas variaciones en la anatomía del nervio alveolar inferior y la arteria maxilar en la disección infratemporal. Durante la disección rutinaria de la cabeza en el cadáver de un varón adulto, fue observada una variación excepcional en el origen del nervio alveolar inferior y su relación con las estructuras circundantes. El nervio alveolar inferior se originaba en el nervio mandibular por dos raíces y la primera parte de la arteria maxilar estaba incorporada entre ambas. El origen embriológico de esta variación y sus implicaciones clínicas es debatido. Dado que la arteria maxilar transcurría entre las dos raíces del nervio alveolar inferior, y el nervio estaba fijado entre el foramen oval y el foramen mandibular, el atrapamiento vásculo-nervioso pudo causar entume-cimiento o dolor de cabeza e interferir con la inyección de anestésicos locales en la fosa infratemporal.  Variaciones anatómicas en esta región deben ser tenidas en cuenta, especialmente en casos de tratamiento fallido de neuralgia del trigémino. Infratemporal fossa is clinically important anatomical area for the delivery of local anesthetic agents in dentistry and maxillofacial surgery. Variations in the anatomy of the inferior alveolar nerve and maxillary artery were studied in infratemporal dissection. During routine dissection of the head in an adult male cadaver an unusual variation in the origin of the inferior alveolar nerve and its relationship with the surrounding structures was observed. The inferior alveolar nerve originated from the mandibular nerve by two roots and the first part of the maxillary artery was incorporated between them. An embryologic origin of this variation and its clinical implications is discussed. Because the maxillary artery runs between the two roots of

  5. Rapid analysis of fungicides in tea infusions using ionic liquid immobilized fabric phase sorptive extraction with the assistance of surfactant fungicides analysis using IL-FPSE assisted with surfactant.

    Science.gov (United States)

    Yang, Miyi; Gu, Yihan; Wu, Xiaoling; Xi, Xuefei; Yang, Xiaoling; Zhou, Wenfeng; Zeng, Haozhe; Zhang, Sanbing; Lu, Runhua; Gao, Haixiang; Li, Jing

    2018-01-15

    A green, simple, inexpensive, and sensitive ionic liquid immobilized fabric phase sorptive extraction method coupled with high performance liquid chromatography was developed for rapid screening and simultaneous determination of four fungicides (azoxystrobin, chlorothalonil, cyprodinil and trifloxystrobin) residues in tea infusions. This IL modified extraction fiber is capable of extracting target analytes directly from complicated tea water matrices with the addition of surfactant. A series of extraction conditions were investigated by one-factor-at-a-time approach and orthogonal test. After a series experiments, the optimum conditions were found to be 10% [HIMIM]NTf2 as coating solution, 2min vortex time, 500μL acetonitrile as dispersive solvent and 2min desorption time. Under the above conditions, the proposed technique was applied to detect fungicides from real tea water samples with satisfactory results. Copyright © 2017. Published by Elsevier Ltd.

  6. Ultrasound-assisted single extraction tests for rapid assessment of metal extractability from soils by total reflection X-ray fluorescence.

    Science.gov (United States)

    De La Calle, I; Cabaleiro, N; Lavilla, I; Bendicho, C

    2013-09-15

    In this work, ultrasound-assisted extraction (UAE) was employed for acceleration of metal extraction from soil samples. After extraction, multielemental analysis (Cr, Mn, Fe, Ni, Cu, Zn and Pb) of EDTA and acetic acid extracts was performed by total reflection X-ray fluorescence spectrometry (TXRF). High-intensity ultrasonic processors, i.e. the ultrasonic probe (50W) and the cup-horn sonoreactor (200W) were applied. Both ultrasonic procedures were compared with a miniaturized version of the single extraction scheme proposed by the Standards, Measurements and Testing program (SM&T). The extraction time with EDTA was reduced from 1h (conventional procedure) to 2 min (ultrasonic probe) or to 10 min (cup-horn sonoreactor). The time required for acetic acid extraction was also reduced from 16 h (conventional procedure) to 6 min (ultrasonic probe) or to 30 min (cup-horn sonoreactor). In addition, the amount of sample and extractants was drastically reduced as a result of the miniaturization implemented in the developed approaches. The combination of UAE and TXRF allows assessing the potential metal mobility and bioavailability in a simple way. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. A rapid ultrasound-assisted dispersive liquid-liquid microextraction followed by ultra-performance liquid chromatography for the simultaneous determination of seven benzodiazepines in human plasma samples.

    Science.gov (United States)

    Fernández, Purificación; González, Cristina; Pena, M Teresa; Carro, Antonia M; Lorenzo, Rosa A

    2013-03-12

    A simple and efficient ultrasound-assisted dispersive liquid-liquid microextraction (UA-DLLME) method has been developed for the determination of seven benzodiazepines (alprazolam, bromazepam, clonazepam, diazepam, lorazepam, lormetazepam and tetrazepam) in human plasma samples. Chloroform and methanol were used as extractant and disperser solvents, respectively. The influence of several variables (e.g., type and volume of dispersant and extraction solvents, pH, ultrasonic time and ionic strength) was carefully evaluated and optimized, using an asymmetric screening design 3(2)4(2)//16. Analysis of extracts was performed by ultra-performance liquid chromatography coupled with photodiode array detection (UPLC-PDA). Under the optimum conditions, two reversed-phases, Shield RP18 and C18 columns were successfully tested, obtaining good linearity in a range of 0.01-5μgmL(-1), with correlation coefficients r>0.996. Quantification limits ranged between 4.3-13.2ngmL(-1) and 4.0-14.8ngmL(-1), were obtained for C18 and Shield RP18 columns, respectively. The optimized method exhibited a good precision level, with relative standard deviation values lower than 8%. The recoveries studied at two spiked levels, ranged from 71 to 102% for all considered compounds. The proposed method was successfully applied to the analysis of seven benzodiazepines in real human plasma samples. Copyright © 2013 Elsevier B.V. All rights reserved.

  8. Rapid determination of rivaroxaban in human urine and serum using colloidal palladium surface-assisted laser desorption/ionization mass spectrometry.

    Science.gov (United States)

    Cheng, Yu-Han; Chen, Wen-Chi; Chang, Sarah Y

    2015-11-15

    Rivaroxaban is a new anticoagulant drug that has recently been introduced for clinical applications. To ensure optimum efficacy while minimizing the risk of toxicity and other adverse effects, a simple and sensitive analytical procedure for monitoring the concentration of rivaroxaban in biological fluids is required. Rivaroxaban was extracted from aqueous solutions by dispersive liquid-liquid microextraction (DLLME). Detection of rivaroxaban was achieved through surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using colloidal palladium as the SALDI matrix. The calibration curve for rivaroxaban in aqueous solutions was linear over the concentration range from 5 to 500 nM. The limit of detection (LOD) for rivaroxaban at a signal-to-noise ratio of 3 was 2 nM. With a sample-to-extract volume ratio of 200, the enrichment factors were calculated to be 141. This method was successfully applied for the determination of rivaroxaban in human urine and serum samples. The LODs for rivaroxaban in urine and serum were calculated to be 6 nM and 60 nM, respectively. The analysis speed, together with the ease of operation and high sensitivity, allows SALDI-MS method to be particularly suitable for the high-throughput screening of rivaroxaban levels in human urine and serum samples. Copyright © 2015 John Wiley & Sons, Ltd.

  9. Rapid analysis of pyrethroid insecticides in aquaculture seawater samples via membrane-assisted solvent extraction coupled with gas chromatography-electron capture detection.

    Science.gov (United States)

    Shi, X Z; Song, S Q; Sun, A L; Liu, J H; Li, D X; Chen, J

    2012-01-21

    A simple, efficient, and environmentally friendly membrane-assisted solvent extraction (MASE) method for the extraction and preconcentration of six pyrethroid insecticides from aquaculture seawater samples followed by gas chromatography-electron capture detection (GC-ECD) was successfully proposed. The operating conditions for MASE, such as the extraction solvent, solvent volume, NaCl concentration, stirring rate, extraction time, and temperature, were optimized. Compared to conventional Florisil-solid phase extraction (SPE), higher extraction recoveries (85.9% to 105.9%) of three spiked levels of the six pyrethroid pesticides in aquaculture seawater were obtained using MASE, and the RSD values were lower than 7.9%. The limits of detection (LOD, signal-to-noise ratio (S/N)=3) and quantification (LOQ, S/N = 10) were in the range of 0.037-0.166 and 0.12-0.55 μg L(-1), respectively. The results demonstrate the excellent applicability of the MASE method in analyzing the six pyrethroid pesticides in aqueous samples. The proposed method exhibited a high potential for routine monitoring analysis of pyrethroid insecticides in seawater samples.

  10. RAPID AND SENSITIVE DETERMINATION OF PALLADIUM USING HOMOGENEOUS LIQUID-LIQUID MICROEXTRACTION VIA FLOTATION ASSISTANCE FOLLOWED BY GRAPHITE FURNACE ATOMIC ABSORPTION SPECTROMETRY

    Directory of Open Access Journals (Sweden)

    Mohammad Rezaee

    2015-05-01

    Full Text Available A method for the determination of trace amounts of palladium was developed using homogeneous liquid-liquid microextraction via flotation assistance (HLLME-FA followed by graphite furnace atomic absorption spectrometry (GFAAS. Ammonium pyrrolidine dithiocarbamate (APDC was used as a complexing agent. This was applied to determine palladium in three types of water samples. In this study, a special extraction cell was designed to facilitate collection of the low-density solvent extraction. No centrifugation was required in this procedure. The water sample solution was added to the extraction cell which contained an appropriate mixture of extraction and homogeneous solvents. By using air flotation, the organic solvent was collected at the conical part of the designed cell. Parameters affecting extraction efficiency were investigated and optimized. Under the optimum conditions, the calibration graph was linear in the range of 1.0-200 µg L-1 with a limit of detection of 0.3 µg L-1. The performance of the method was evaluated for the extraction and determination of palladium in water samples and satisfactory results were obtained. In order to verify the accuracy of the approach, the standard addition method was applied for the determination of palladium in spiked synthetic samples and satisfactory results were obtained.

  11. Rapid synthesis of water-dispersible superparamagnetic iron oxide nanoparticles by a microwave-assisted route for safe labeling of endothelial progenitor cells.

    Science.gov (United States)

    Carenza, Elisa; Barceló, Verónica; Morancho, Anna; Montaner, Joan; Rosell, Anna; Roig, Anna

    2014-08-01

    We synthesize highly crystalline citrate-coated iron oxide superparamagnetic nanoparticles that are stable and readily dispersible in water by an extremely fast microwave-assisted route and investigate the uptake of magnetic nanoparticles by endothelial cells. Nanoparticles form large aggregates when added to complete endothelial cell medium. The size of the aggregates was controlled by adjusting the ionic strength of the medium. The internalization of nanoparticles into endothelial cells was then investigated by transmission electron microscopy, magnetometry and chemical analysis, together with cell viability assays. Interestingly, a sevenfold more efficient uptake was found for systems with larger nanoparticle aggregates, which also showed significantly higher magnetic resonance imaging effectiveness without compromising cell viability and functionality. We are thus presenting an example of a straightforward microwave synthesis of citrate-coated iron oxide nanoparticles for safe endothelial progenitor cell labeling and good magnetic resonance cell imaging with potential application for magnetic cell guidance and in vivo cell tracking. Copyright © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  12. Rapid identification of pathogens directly from blood culture bottles by Bruker matrix-assisted laser desorption laser ionization-time of flight mass spectrometry versus routine methods.

    Science.gov (United States)

    Jamal, Wafaa; Saleem, Rola; Rotimi, Vincent O

    2013-08-01

    The use of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identification of microorganisms directly from blood culture is an exciting dimension to the microbiologists. We evaluated the performance of Bruker SepsiTyper kit™ (STK) for direct identification of bacteria from positive blood culture. This was done in parallel with conventional methods. Nonrepetitive positive blood cultures from 160 consecutive patients were prospectively evaluated by both methods. Of 160 positive blood cultures, the STK identified 114 (75.6%) isolates and routine conventional method 150 (93%). Thirty-six isolates were misidentified or not identified by the kit. Of these, 5 had score of >2.000 and 31 had an unreliable low score of time using the STK was 35 min, including extraction steps and 30:12 to 36:12 h with routine method. The STK holds promise for timely management of bacteremic patients. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Chemometrics-assisted excitation-emission fluorescence analytical data for rapid and selective determination of optical brighteners in the presence of uncalibrated interferences

    Science.gov (United States)

    Gholami, Ali; Masoum, Saeed; Mohsenikia, Atefeh; Abbasi, Saleheh

    2016-01-01

    This study describes a novel approach for the simultaneous determination of CBS-X and CXT as widely used optical brighteners in household detergent, by combining the advantage of the high sensitivity of molecular fluorescence, and the selectivity of second-order chemometric methods. The proposed method is assisted by second-order chemometric analyses employing the PARAFAC, SWATLD and APTLD that help us to determine CBS-X and CXT in laundry powders and environmental samples, through the unique decomposition of the three-way data array. Proposed method can provide the extraction of relative concentrations of the analytes, as well as the spectral profiles. This approach achieves the second-order advantage and in principle could be able to overcome the spectral uncalibrated interference problems in the determination of CBS-X and CXT at the ng g- 1 level. By spiking the known concentrations of these compounds to the real samples, the accuracy of the proposed methods was validated and recoveries of the spiked values were calculated. High recoveries (90.00%-113.33%) for the spiked laundry powders and real environmental samples indicate the present method successfully faces this complex challenge without the necessity of applying separation and preconcentration steps in environmental contaminations.

  14. Rapid and sensitive analysis of nine fungicide residues in chrysanthemum by matrix extraction-vortex-assisted dispersive liquid-liquid microextraction.

    Science.gov (United States)

    Xue, Jiaying; Chen, Xiaochu; Jiang, Wenqing; Liu, Fengmao; Li, Huichen

    2015-01-15

    A simple sample pretreatment for simultaneous determination of nine fungicides (triadimefon, picoxystrobin, kresoxim-methyl, diniconazole, epoxiconazole, trifloxystrobin, triticonazole, difenoconazole, and azoxystrobin) in chrysanthemum was developed using matrix extraction-vortex-assisted dispersive liquid-liquid microextraction (ME-VADLLME) prior to gas chromatography with electron capture detection. The target fungicides were firstly extracted with acetonitrile and cleaned with the mixture of primary secondary amine and graphite carbon black. The VADLLME procedure was performed by using toluene with lower density than water as the extraction solvent and the acetonitrile extract as the dispersive solvent, respectively. After vortexing and centrifugation, the fine droplet of toluene was collected on the upper of the mixed toluene/acetonitrile/water system using a 0.1-mL pipettor. Under the optimum conditions, the relative recoveries ranged from 73.9 to 95.1% with relative standard deviations of 3.5-9.7% for all of the analytes. The limits of detection were in the range of (0.005-0.05)×10(-3) mg kg(-1). In the proposed method, the ME step provides more effective cleanup for the chrysanthemum matrix, and VADLLME introduces higher sensitivity with the remarkable enrichment factors up to 88-fold compared with the conventional QuEChERS or SPE. The good performance has demonstrated that ME-VADLLME has a strong potential for application in the multi-residue analysis of complex matrices. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry as a tool for rapid diagnosis of potentially toxigenic Corynebacterium species in the laboratory management of diphtheria-associated bacteria.

    Science.gov (United States)

    Konrad, R; Berger, A; Huber, I; Boschert, V; Hörmansdorfer, S; Busch, U; Hogardt, M; Schubert, S; Sing, A

    2010-10-28

    The rapid identification of the potentially toxigenic Corynebacterium species, C. diphtheriae, C. ulcerans and C. pseudotuberculosis is essential for diagnosis and treatment of diphtheria and diphtheria-like diseases. We used matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDIT-OF MS) in comparison with classical microbiological and molecular methods on 116 Corynebacterium strains. All 90 potentially toxigenic Corynebacterium strains collected by the German National Consiliary Laboratory on Diphtheria in a period of more than ten years were correctly identified by MALDI-TOF MS. We propose an algorithm for fast and reliable diagnosis of diphtheria incorporating MALDI-TOF MS, real-time tox PCR and Elek testing.

  16. Effects of orthopedic maxillary expansion on nasal cavity size in growing subjects: a low dose computer tomography clinical trial.

    Science.gov (United States)

    Cordasco, Giancarlo; Nucera, Riccardo; Fastuca, Rosamaria; Matarese, Giovanni; Lindauer, Steven J; Leone, Pietro; Manzo, Paolo; Martina, Roberto

    2012-11-01

    The aim of this retrospective clinical trial was to evaluate the effects of rapid maxillary expansion on skeletal nasal cavity size in growing subjects by use of low dose computer tomography. Eight Caucasian children (three male; five female) with a mean age of 9.7 years (SD±1.41) were the final sample of this research that underwent palatal expansion as a first phase of orthodontic treatment. The maxillary expander was banded to the upper first molars and was activated according a rapid maxillary expansion protocol. Low-dose computer tomography examinations of maxilla and of the low portion of nasal cavity were performed before inserting the maxillary expander (T0) and at the end of retention (T1), 7 months later. A low-dose computer tomography protocol was applied during the exams. Image processing was achieved in 3 steps: reslicing; dental and skeletal measurements; skeletal nasal volume computing. A set of reproducible skeletal and dental landmarks were located in the coronal passing through the first upper right molar furcation. Using the landmarks, a set of transverse linear measurements were identified to estimate maximum nasal width and nasal floor width. To compute the nasal volume the lower portion of the nasal cavity was set as region of interest. Nasal volume was calculated using a set of coronal slices. In each coronal slice, the cortical bone of the nasal cavity was identified and selected with a segmentation technique. Dependent t-tests were used to evaluate changes due to expansion. For all tests, a significance level of Pmaxillary expansion produced significant increases of linear transverse skeletal measurements, these increments were bigger in the lower portion of the nasal cavities: nasal floor width (+3.15 mm; SD ± 0.99), maximum nasal width (+2.47 mm; SD ± 0.99). Rapid maxillary expansion produced significant increment of the total nasal volume (+1.27 cm(3) ± SD 0.65). The anterior volume increase was 0.58 cm(3) while the posterior one was

  17. Effect of maxillary sinus floor augmentation without bone grafts

    Directory of Open Access Journals (Sweden)

    D Shiva Kumar

    2013-01-01

    Full Text Available Objective: The objective of the present review was to determine the effectiveness of maxillary sinus floor augmentation without bone grafts using lateral window technique. Materials and Methods: PubMed and Cochrane databases were searched for relevant articles. We also included articles by hand search until June 2012. The analysis included both human and animal studies which satisfied the following criteria: Minimum of 6 months follow-up, no use of bone grafts, and lateral window approach to the sinus. Results: We included 22 articles in the review. A descriptive analysis of the constructed evidence tables indicated that there is evidence of predictable a mount of bone formation in the maxillary sinus augmentation without the use of bone grafts. Conclusion: Within the limits of the articles and data available, maxillary sinus augmentation without bone graft might be considered effective inpredictable bone formation.

  18. The value of panoramic radiography in assessing maxillary sinus inflammation

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Bong Hae; Jung, Yun Hoa; Nah, Kyung Soo [Department of Oral and Maxillofacial Radiology, College of Dentistry, Pusan National University, Pusan (Korea, Republic of)

    2008-12-15

    To evaluate the value of panoramic radiography in diagnosing maxillary sinus inflammation. A total of 214 maxillary sinuses from 114 panoramic radiographs were assessed in this study. Two independent experienced oral radiologists evaluated the images in random order for sinus inflammation. Using Cone beam CT images as the gold standard, the sensitivity and specificity of panoramic radiography were calculated, and inter- and intraobserver agreement for panoramic interpretation were obtained. The mean sensitivity and specificity of panoramic radiography were 81.0% and 85.6%, respectively. The weighted kappas for inter- and intraobserver agreement of panoramic radiography were 0.56 and 0.60, respectively. Panoramic radiography is a reasonably accurate method for diagnosing maxillary sinus inflammation and can be used for screening. However, additional examinations should be considered in patients with potentially significant pathology.

  19. Maxillary necrosis by mucormycosis. a case report and literature review.

    Science.gov (United States)

    Auluck, Ajit

    2007-09-01

    The maxilla rarely undergoes necrosis due to its rich vascularity. Maxillary necrosis can occur due to bacterial infections such as osteomyelitis, viral infections such as herpes zoster or fungal infections such as mucormycosis, aspergillosis etc. Mucormycosis is an opportunistic fulminant fungal infection, which mainly infects immunocompromised patients. The infection begins in the nose and paranasal sinuses due to inhalation of fungal spores. The infection can spread to orbital and intracranial structures either by direct invasion or through the blood vessels. The fungus invades the arteries leading to thrombosis that subsequently causes necrosis of hard and soft tissues. We report a case of maxillary necrosis by mucormycosis in an uncontrolled diabetic patient to emphasize early diagnosis of this potentially fatal fungal infection. We briefly discuss different diseases which can lead to maxillary necrosis and review the current concepts in management of mucormycosis. Early diagnosis and prompt treatment can reduce the mortality and morbidity of this lethal fungal infection.

  20. Posterior maxillary anatomy: implications for Le Fort I osteotomy.

    Science.gov (United States)

    Cheung, L K; Fung, S C; Li, T; Samman, N

    1998-10-01

    The most common site of haemorrhage in maxillary osteotomies is the posterior maxilla. Better understanding of the anatomy in this region may minimize possible vascular complications. The aim of the study was to study the osteology of the posterior maxillary region and establish clinical safety guidelines for the Le Fort I osteotomy Thirty human dry skulls were selected and assessed by a combination of direct inspection, computerized imaging and computed tomography (CT) scan analysis. Results showed that the presence of maxillary third molars influenced the transverse angulation of the posterior vertical cut. Synostosis of the pterygomaxillary junction was noted in 12% of samples. The mean length of the medial sinus wall from the piriform rim to the descending palatine canal at the Le Fort I level was 34 mm. The three-dimensional CT-reconstructed descending palatine canal ran at 60 degrees anteroinferiorly to the palatine plane and slightly medially to the exit through the greater palatine foramen.

  1. UNILATERAL DISTALIZATION OF MAXILLARY MOLAR BY PENDULUM APPLIANCE

    Directory of Open Access Journals (Sweden)

    Safra Mauna

    2006-04-01

    Full Text Available Pendulum appliance is one of intraoral appliances to distalize molars for correction of class II molar relationship or space gaining in the maxillary arch. Its major advantages are: no need to depend on patient compliance; ease of fabrication; and better patient acceptance. In this case, 22 years old female patient with class II division 2 malocclusion was treated with pendulum appliance for unilateral distalization of the maxillary molar teeth. Pendulum can distalize second molar until 4 mm in 4 months and continues to distalize first molar in 3 months. Nevertheless, relapse 2 mm happens during anterior retraction. This case has shown that pendulum is an effective and reliable appliance for distalizing maxillary molars. However, molar distalization is at the expense of moderate anchorage loss during anterior retraction, which could possibly be reduced if the anchor unit is adequately reinforced.

  2. Closing a Large Maxillary Median Diastema using Bapat Power Arm

    Science.gov (United States)

    Singh, Chanchal; Bandejiya, Prashant

    2017-01-01

    Aim The aim of this study is to present a case of large maxillary median diastema closed by bodily movement of central incisors using Bapat power arm (BPA). Materials and methods After extraction of mesiodens, a power chain with a force of 120 gm was applied to BPA ligated to preadjusted edgewise brackets bonded to maxillary central incisors to move them over round steel wire for closure of resultant diastema. Bonded retainer was placed after the closure of median diastema. Results The median diastema was completely closed in 5 months period with almost bodily movement of incisors, which was confirmed by periapical X-ray. Conclusion Bapat power arm was efficient in closing diastema without any discomfort or injury and was well accepted by the patient. How to cite this article Bapat SM, Singh C, Bandejiya P. Closing a Large Maxillary Median Diastema using Bapat Power Arm. Int J Clin Pediatr Dent 2017;10(2):201-204. PMID:28890624

  3. Unevenness of the apical constriction in human maxillary central incisors.

    Science.gov (United States)

    Olson, David G; Roberts, Steven; Joyce, Anthony P; Collins, D Edward; McPherson, James C

    2008-02-01

    This study examined the incisoapical extent of the apical constriction in 45 human maxillary central incisors. The null hypothesis was that the apical constriction is a flat ring. Our working hypothesis was that the constriction is actually uneven or "skewed" as it traces a path around the circumference of the canal. Teeth were split and imaged with 25x magnification, and the most apical and coronal limits of the apical constriction were identified and measured. Analysis of the data indicates that a majority (>70%) of maxillary central incisors exhibit an unevenness or "skew" of the apical constriction of greater than 100 microm in the incisoapical dimension, with a maximum measured skew of 385 microm. On the basis of the results of this study, a statistically significant (P apical constriction around its circumference was confirmed in maxillary central incisors.

  4. Maxillary Chronic Osteomyelitis Caused by Domestic Violence: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Tamyris Inácio Oliveira

    2014-01-01

    Full Text Available Maxillary osteomyelitis is a rare condition defined as inflammation of the bone primarily caused by odontogenic bacteria, with trauma being the second leading cause. The present report documents a rare case of maxillary osteomyelitis in a 38-year-old female who was the victim of domestic violence approximately a year prior to presentation. Intraoral examination revealed a lesion appearing as exposed bony sequestrum, with significant destruction of gingiva and alveolar mucosa in the maxillary right quadrant, accompanied by significant pain, local edema, and continued purulence. Teeth numbers 11, 12, 13, 14, and 15 were mobile, not responsive to percussion, and nonvital. Treatment included antibiotic therapy for seven days followed by total enucleation of the necrotic bone tissue and extraction of the involved teeth. Microscopic findings confirmed the clinical diagnosis of chronic suppurative osteomyelitis. Six months postoperatively, the treated area presented complete healing and there was no sign of recurrence of the lesion.

  5. Multiple talon cusps on maxillary central incisor: A case report

    Directory of Open Access Journals (Sweden)

    Suresh KV

    2017-06-01

    Full Text Available Dental anomalies affecting the teeth are relatively common. Simultaneous occurrence of multiple dental abnormalities in a single tooth is uncommon and relatively rare. One such abnormality routinely encountered in dental clinics is the talon cusp. It is also referred to as dens evaginatus, characterized by the presence of an accessory cusp-like structure projecting from the cingulum of anterior teeth. It has an increased predilection for maxillary teeth and permanent dentition. Although numerous cases of talon cusp have been reported in the literature, occurrence of multiple talon cusps in maxillary central incisors has not been found in the literature. This case report highlights the presence of talon cusps in maxillary anterior teeth with multiple impacted supernumerary teeth.

  6. Etiologies and Treatments of Odontogenic Maxillary Sinusitis: A Systematic Review

    Science.gov (United States)

    Akhlaghi, Fahimeh; Esmaeelinejad, Mohammad; Safai, Pooria

    2015-01-01

    Context: Maxillary sinusitis is an important issue in dentistry and maxillofacial surgery. This study aims to present a systematic review of etiologies and treatments of odontogenic maxillary sinusitis. Evidence Acquisition: An electronic database search was performed based on related MeSH keywords. Articles published between January 2001 and December 2014 was selected according to the inclusion criteria. The information extracted from various studies was categorized in various tables. Results: The study selected 19 studies. In most studies, oroantral fistula (OAF) was the most common etiology of odontogenic sinusitis. Alpha-hemolytic streptococcus was the most common flora in sinusitis with dental origin. The literature shows that the Caldwell-Luc approach may be the best method for treating sinusitis in cases of displaced teeth. Conclusions: OAF is a common cause of odontogenic maxillary sinusitis and may easily be treated by endoscopy and fistula closure. Maxillofacial surgeons and dentists should consider this problem to avoid misdiagnosis and prevent complications. PMID:26756016

  7. Methylene blue mediated laser therapy of maxillary sinusitis

    Science.gov (United States)

    Genina, E. A.; Bashkatov, A. N.; Chikina, E. E.; Knyazev, A. B.; Mareev, O. V.; Tuchin, V. V.

    2006-07-01

    The purpose of the present work is a clinical study of photodynamic therapy of maxillary sinusitis. 0.1%-Methylene Blue aqueous solution in combination with He-Ne laser irradiation (632.8 nm) have been used for treatment of maxillary sinus mucous of patients with acute and chronic maxillary sinusitis. The differences between the results of the treatment with dye and light versus treatment with a drug for every group of patients were statistically analyzed by Student’s t test. The efficacy of the photodynamic therapy was estimated with the use of the following criteria: the state of respiration, olfaction, duration of purulent discharge, reconstruction of transport function of ciliary epithelium, etc. The obtained results have shown that the photodynamic therapy is effective in comparison with conservative methods of treatment of the disease.

  8. Closing a Large Maxillary Median Diastema using Bapat Power Arm.

    Science.gov (United States)

    M Bapat, Shirish; Singh, Chanchal; Bandejiya, Prashant

    2017-01-01

    The aim of this study is to present a case of large maxillary median diastema closed by bodily movement of central incisors using Bapat power arm (BPA). After extraction of mesiodens, a power chain with a force of 120 gm was applied to BPA ligated to preadjusted edgewise brackets bonded to maxillary central incisors to move them over round steel wire for closure of resultant diastema. Bonded retainer was placed after the closure of median diastema. The median diastema was completely closed in 5 months period with almost bodily movement of incisors, which was confirmed by periapical X-ray. Bapat power arm was efficient in closing diastema without any discomfort or injury and was well accepted by the patient. Bapat SM, Singh C, Bandejiya P. Closing a Large Maxillary Median Diastema using Bapat Power Arm. Int J Clin Pediatr Dent 2017;10(2):201-204.

  9. Evaluation the success of osseointegrated implants in maxillary sinus grafts

    Directory of Open Access Journals (Sweden)

    Rubens Eduardo Gigli

    2008-01-01

    Full Text Available Objective: To analyze implants placed in maxillary sinus grafts with biomaterial of bovine origin and platelet-rich plasma, observing bone neoformation and the clinical and histologic success rate presented.Methods: Analysis of the clinical findings was based on 36 maxillary sinus grafts with 101 implants placed in 30 patients with a mean age of 47 years, and the histologic analysis, based on nine samples of the 36 grafts performed, with a mean interval of 7.5 months time of the graft, the majority of patients being men with a mean age of 42 years. Results: Clinically, 91 implants placed were osseointegrated.Conclusion: Based on the results presented, it was concluded that when implants are placed in the maxillary sinus region grafted with biomaterial, they present a high success rate. ISRCTN24003246

  10. Skeletal Anchorage using Mini-implants in the Maxillary Tuberosity Region

    Directory of Open Access Journals (Sweden)

    Sundaram Venkateswaran

    2013-01-01

    The case reports discussed in the article demonstrates the ability of mini-implants when placed in the maxillary tuberosity for en masse distalization of the entire maxillary dentition, its advantages and biomechanics.

  11. Analysis of the dental morphology of Plio-Pleistocene hominids. V. Maxillary postcanine tooth morphology

    National Research Council Canada - National Science Library

    Wood, B A; Engleman, C A

    1988-01-01

    A total of 139 maxillary molar crowns and 79 maxillary premolar crowns, from at least 98 individual East and Southern African Plio-Pleistocene hominids, has been subjected to detailed morphometric analysis...

  12. Análise comparativa da expansão maxilar com três marcas de parafusos com limitador posterior: ensaio laboratorial em Typodont Comparative analysis of rapid maxillary expansion using three brands of fan-type expander screw: laboratory trial using typodont

    Directory of Open Access Journals (Sweden)

    Ricardo Damo Meneguzzi

    2011-10-01

    Full Text Available INTRODUÇÃO: nos pacientes com fissura labiopalatina, observa-se, usualmente, uma severa atresia da maxila, especialmente na região anterior da arcada, cujo tratamento envolve expansão maxilar. OBJETIVO: o propósito desse estudo foi avaliar o padrão de expansão de três marcas de parafusos com limitador posterior na correção da deficiência transversa. MÉTODOS: foram realizadas 18 expansões em Typodont, com 6 simulações para cada grupo: G1 - parafuso Dentaurum®, G2 - parafuso Leone®, e G3 - parafuso Morelli®. Foram realizadas, para cada ensaio, 13 ativações de 2/4 de volta, totalizando 5,2mm de abertura do parafuso. Definiram-se os momentos das medições em inicial (T1, metade das ativações (T2 e final (T3. Com o auxílio de um paquímetro, foram medidas as seguintes distâncias: interprimeiros pré-molares (IP1, interssegundos pré-molares (IP2, intermolares (IM e comprimento da arcada (CA. Os dados obtidos foram submetidos aos testes de Kolmogorov-Smirnov, de Tukey, de Friedman e ANOVA. RESULTADOS: observou-se que todos os grupos apresentaram um padrão de abertura em forma de "V" com maior expansão na região anterior da arcada, sendo mais expressivo no grupo G3 (29,58% em IP1 e 9,73% em IM. O aumento na medida CA foi semelhante para os grupos G1 e G3 (+12,65% e +12,13%, respectivamente, com menor valor para o G2 (+8,23%. CONCLUSÕES: concluiu-se que todos os parafusos com limitador posterior utilizados nesse estudo podem ser empregados no tratamento da deficiência transversa da arcada. Entretanto, o parafuso Morelli® apresentou maior abertura na região anterior em relação à posterior, característica importante no tratamento de pacientes com fissura labiopalatina. Recomenda-se a realização de estudos clínicos para confirmação desses achados.INTRODUCTION: Severe constriction of the maxillary arch, especially in the anterior part of the maxilla, is a common finding in cleft lip and palate patients. The usual

  13. The choice of ultrasound assisted extraction coupled with spectrophotometric for rapid determination of gallic acid in water samples: Central composite design for optimization of process variables.

    Science.gov (United States)

    Pooralhossini, Jaleh; Ghaedi, Mehrorang; Zanjanchi, Mohammad Ali; Asfaram, Arash

    2017-01-01

    A sensitive procedure namely ultrasound-assisted (UA) coupled dispersive nano solid-phase microextraction spectrophotometry (DNSPME-UV-Vis) was designed for preconcentration and subsequent determination of gallic acid (GA) from water samples, while the detailed of composition and morphology and also purity and structure of this new sorbent was identified by techniques like field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD) and Energy-dispersive X-ray spectroscopy (EDX) techniques. Among conventional parameters viz. pH, amount of sorbent, sonication time and volume of elution solvent based on Response Surface Methodology (RSM) and central composite design according to statistics based contour the best operational conditions was set at pH of 2.0; 1.5mg sorbent, 4.0min sonication and 150μL ethanol. Under these pre-qualified conditions the method has linear response over wide concentration range of 15-6000ngmL(-1) with a correlation coefficient of 0.9996. The good figure of merits like acceptable LOD (S/N=3) and LOQ (S/N=10) with numerical value of 2.923 and 9.744ngmL(-1), respectively and relative recovery between 95.54 and 100.02% show the applicability and efficiency of this method for real samples analysis with RSDs below 6.0%. Finally the method with good performance were used for monitoring under study analyte in various real samples like tap, river and mineral waters. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Root Length and Anatomy of Impacted Maxillary Canines in Patients with Unilateral Maxillary Canine Impaction

    Directory of Open Access Journals (Sweden)

    Mostfa Shahabi

    2017-09-01

    Full Text Available Introduction: Canine impaction is a common occurrence. In this study, we sought to investigate the root anatomy and length of impacted canines and lateral incisor adjacent to impacted maxillary canine. Materials and Methods: In this retrospective study, three-dimensional tomographic imaging was performed on 26 patients with unilateral maxillary canine impaction. In this study, we evaluated root length and anatomy of impacted canines, in terms of resorption intensity and curvature, with Planmeca Romexis Viewer 4.0. Furthermore, crown shape as well as root length and anatomy of the lateral incisors adjacent to impacted canines were investigated and compared with the other side on the dental arch, where canine eruption was normal. Results: Root length of impacted canines was significantly lower than that of normal canines (P=0.011. There were no significant differences between root length of lateral incisors adjacent to impacted canines and root length of lateral incisors adjacent to normal canines (P=0.221. Moreover, the resorption intensity of the adjacent lateral incisors was higher than that of the impacted canines. No significant differences were noted in root resorption intensity between the lateral incisors adjacent to the imacted canines and the lateral incisors adjacent to normal canines (P=0.36. In addition, resorption intensity was significantly higher in impacted canines than in normal canines (P=0.024. Root anatomy of impacted canines was not significantly different from that of normal canines (P=0.055. The crown shape of the lateral incisors adjacent to impacted canines was not significantly different from that of the lateral incisors adjacent to normal canines (P=0.052. Conclusion: Impaction can probably affect root length and canine resorption severity. However, root and crown shape of lateral incisors cannot always be associated with canine impaction.

  15. A Rapid Centrifugation-Assisted Solid-Phase Extraction and Liquid Chromatography Method for Determination of Loureirin A and Loureirin B of Dragon's Blood Capsules in Rat Plasma and Urine After Oral Administration.

    Science.gov (United States)

    Chen, Xiaoshuang; Li, Gaofeng; Ma, Shangfang; Hu, Xujia

    2015-07-01

    A simple, sensitive and rapid centrifugation-assisted solid-phase extraction (SPE) with high-performance liquid chromatography (SPE-HPLC) method was developed for simultaneous determination of the metabolites loureirin A and loureirin B from Dragon's blood in rat plasma and urine. The development of the extraction procedure included optimization of some important extraction phases. After evaluation, the metabolites of Dragon's blood were extracted by centrifugation-assisted SPE and separated by using HPLC. This method showed good linearity (r(2) > 0.99), and in the rat plasma and urine, the recoveries were 93.1 and 95.7% for loureirin A and were 90.1 and 94.2% for loureirin B. The relative standard deviation (RSD) values of intraday and interday precision in rat plasma and urine for loureirin A were <3.84 and 2.01%, respectively. The RSD values of the intraday and interday precision in rat plasma and urine for loureirin B were below 4.25 and 5.83%, respectively. Thus, the established method is suitable for metabolism studies of loureirin A and loureirin B in rat plasma and urine. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. COMPARISON OF CONE-BEAM COMPUTED TOMOGRAPHY AND PANORAMIC RADIOGRAPHS IN DETECTING MAXILLARY SINUS SEPTA

    Directory of Open Access Journals (Sweden)

    Meryem TORAMAN-ALKURT

    2016-10-01

    Full Text Available Purpose: The purpose of this retrospective study was to compare the performance of cone-beam computed tomography (CBCT and panoramic radiography in detecting the presence and location of maxillary sinus septa. Materials and methods: This study included radiographic examination of 104 maxillary sinuses of 52 individuals (26 females, 50% and 26 males, 50% whose panoramic radiographs and CBCT images were obtained for several dental causes which were examined by the consensus of four dentomaxillofacial radiologists. The posterior maxillary segments in proximity of maxillary sinus were classified as edentulous and dentate maxillary segments. The location of maxillary sinus septa was classified as primary septa and secondary septa according to the presence of maxillary tooth at the affected site. The maxillary sinus septa were divided into three categories (anterior, middle and posterior according to its relation with posterior maxillary teeth. Data were statistically analyzed with chi-square and Fisher’s exact tests. Results: The septa were found in 23.1% and 29.8% of the maxillary sinuses on panoramic radiography and CBCT images, respectively. The majority of maxillary sinus septa were observed in dentate posterior maxillary segments on both panoramic (45.8% radiography and CBCT (64.5% images. Statistically significant differences (p<0.001 were found between panoramic radiography and CBCT images for presence, location and neighborhood with the posterior maxillary teeth of maxillary sinus septa. Conclusion: The results of this study demonstrated the low reliability of panoramic radiography images in the detection of maxillary sinus septa. CBCT images can provide valuable information to the clinicians about the presence and location of maxillary sinus septa.

  17. 〈Case Reports〉Clinical study of six patients with foreign bodies into maxillary sinus

    OpenAIRE

    Matsunaga, Kazuhide; Ehara, Hiroki; Enomoto, Akifumi; Uchihashi, Takayuki; Morikawa, Hiroki; Mukai, Takao; Tamai, Nana; Higashi, Naoya; Doi Katsumi; Hamada, Suguru

    2017-01-01

    [Abstract]Six patients with iatrogenic and noniatrogenic foreign bodies in the maxillary sinus are presented. Four patients had iatrogenic foreign bodies, including a dental implant, a maxillary wisdom tooth, a maxillary wisdom tooth root and a dental root canal filler. The other two patients with non-iatrogenic foreign bodies fractured an interdental brush while cleaning their teeth and it entered the maxillary sinus. For surgical extraction of foreign bodies, the intra-oral and trans-nasal ...

  18. Rapid continuous microwave-assisted synthesis of silver nanoparticles to achieve very high productivity and full yield: from mechanistic study to optimal fabrication strategy

    Energy Technology Data Exchange (ETDEWEB)

    Dzido, Grzegorz, E-mail: gdzido@polsl.pl [Silesian University of Technology, Department of Chemical Engineering and Process Design, Faculty of Chemistry (Poland); Markowski, Piotr [Silesian University of Technology, Department of Inorganic, Analytical Chemistry and Electrochemistry, Faculty of Chemistry (Poland); Małachowska-Jutsz, Anna [Silesian University of Technology, Department of Environmental Biotechnology, Faculty of Energy and Environmental Engineering (Poland); Prusik, Krystian [University of Silesia, Institute of Materials Science (Poland); Jarzębski, Andrzej B. [Silesian University of Technology, Department of Chemical Engineering and Process Design, Faculty of Chemistry (Poland)

    2015-01-15

    Systematic studies of silver nanoparticle synthesis in a continuous-flow single-mode microwave reactor using polyol process were performed, revealing that the synthesis is exceptionally effective to give very small metal particles at full reaction yield and very high productivity. Inlet concentration of silver nitrate or silver acetate, applied as metal precursors, varied between 10 and 50 mM, and flow rates ranged from 0.635 to 2.5 dm{sup 3}/h, to give 3–24 s reaction time. Owing to its much higher reactivity, silver acetate was shown to be far superior substrate for the synthesis of small (10–20 nm) spherical silver nanoparticles within a few seconds. Its restricted solubility in ethylene glycol, applied as the solvent and reducing agent, appeared to be vital for effective separation of the stage of particle growth from its nucleation to enable rapid synthesis of small particles in a highly loaded system. This was not possible to obtain using silver nitrate. All the observations could perfectly be explained by a classical LaMer–Dinegar model of NPs’ formation, but taking into account also nonisothermal character of the continuous-flow process and acetate dissolution in the reaction system. The performed studies indicate an optimal strategy for the high-yield fabrication of metal particles using polyol method.

  19. Abscess of the orbit arising 48 h after root canal treatment of a maxillary first molar.

    Science.gov (United States)

    Koch, F; Breil, P; Marroquín, B B; Gawehn, J; Kunkel, M

    2006-08-01

    To discuss a rare, but severe complication arising following routine root canal treatment. An orbital abscess is reported that occurred following routine root canal treatment. A young, healthy female patient, with no history of chronic paranasal infection had undergone root canal treatment of the right maxillary first molar. On hospital admission, she presented with extensive periorbital swelling and discreet diplopia. Computed tomography imaging identified massive purulent sinusitis and subsequent involvement of the orbit via the inferior and medial orbital wall within 48 h after completion of root canal treatment. Immediate surgical drainage of the maxillary sinus and the orbit was established and a high dose of perioperative antibiotics (Amoxicillin/Clavulanic acid, Gentamycin, Metronidazole) were administered. Vision remained undisturbed and mobility of the globe recovered within 10 days. Rapid exacerbation of a periapical inflammation may occur following root canal treatment and may even involve the orbit. A typical speed of disease progression or ophthalmic symptoms should alert the clinician to at least consider unusual early orbital spread of odontogenic infection. When extra-alveolar spread and especially orbital spread is suspected, immediate referral to a maxillofacial or other specialized unit is mandatory.

  20. The effect of a maxillary lip bumper on tooth positions

    OpenAIRE

    Häsler, R.; Ingervall, B.

    2017-01-01

    The effect of the use of a lip bumper with anterior vestibular shields on the maxilla was studied in twenty-two 9-14 year-old children with a space deficiency in the maxillary dental arch. The lip bumper was used for 1 year. The effect of the treatment was evaluated from dental casts and profile cephalograms made before and after treatment. Both the width of the maxillary dental arch at the premolars and the length of the arch increased significantly by about 2 mm. The effect of the treatment...

  1. Uncontrolled Epistaxis Secondary to Traumatic Pseudoaneurysm of the Maxillary Artery

    Directory of Open Access Journals (Sweden)

    Eelam Adil

    2011-01-01

    Full Text Available We describe a rare case of traumatic pseudoaneurysm of the maxillary artery following a fall. The patient presented with epistaxis that could not be controlled with anterior and posterior nasal packing. She was urgently taken to the angiography suite for evaluation and ultimately underwent embolization of a left maxillary artery pseudoaneurysm with 500–700 micron Contour PVA followed by coiling with two 3 mm Tornado coils. Bleeding subsided after embolization, and the patient suffered no neurologic sequelae.

  2. Effective Maxillary Protraction with Tandem Traction Bow Appliance

    Directory of Open Access Journals (Sweden)

    Pravin Kumar S Marure

    2014-01-01

    Full Text Available Tandem traction bow appliance (TTBA promotes patient compliance, because it is more esthetic and comfortable than extraoral appliances. TTBA should be used only in case where maxillary deficiency and normal mandible is present. Advantages of it includes good oral hygiene, early treatment of any Class III malocclusion, optimal retention, distribution of the forces for protraction to all maxillary teeth, free mandibular movement. It can be used in conjunction with fixed appliances if necessary. This paper includes two case reports. The treatment results in both the cases demonstrated significant skeletal and dental response to TTBA therapy. Skeletal change was primarily a result of anterior movement of the maxilla.

  3. Laser therapy of acute and chronic maxillary sinusitis

    Science.gov (United States)

    Bashkatov, Alexey N.; Genina, Elina A.; Chikina, Elena E.; Meglinski, Igor V.; Tuchin, Valery V.; Knyazev, Anatoly B.; Mareev, Oleg V.

    2006-06-01

    The clinical results of photodynamic therapy of maxillary sinusitis have been presented. 0.1%-Methylene Blue aqueous solution in combination with He-Ne laser irradiation (632.8 nm) has been used for treatment of patients with acute and chronic maxillary sinusitis. Efficacy of the photodynamic therapy was estimated with the use of the following criteria: the state of respiration, olfaction, duration of purulent discharge, reconstruction of transport function of ciliary epithelium, etc. The obtained results have shown that the photodynamic therapy is effective in comparison with conservative methods of treatment of the diseases.

  4. Relapse of a maxillary median diastema: closure and permanent retention.

    Science.gov (United States)

    Mattos, Claudia Trindade; da Silva, Dayanne Lopes; Ruellas, Antonio Carlos de Oliveira

    2012-01-01

    The purpose of this article was to describe the closure of a maxillary median diastema of a 26-year-old woman that had been corrected before during orthodontic treatment but reopened after dental trauma in a car accident. A clear esthetic device made from a tray like those used for home bleaching was used, providing a comfortable, nearly undetectable, and efficient solution. A permanent fixed retainer was bonded again to the maxillary central incisors to prevent relapse. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  5. Aplasia and hypoplasia of the maxillary sinus: A case series

    Directory of Open Access Journals (Sweden)

    Nasim Jafari-Pozve

    2014-01-01

    Full Text Available Maxillary sinus aplasia and hypoplasia are rare conditions that can cause symptoms such as headaches and voice alteration. The majority of patients are asymptomatic, but these conditions must be noticed for importance of differential diagnosis such as infection and neoplasms. Conventional radiographs could not differentiate between inflammatory mucosal thickening, neoplasm, and hypoplasia of the sinus. Computed tomography (CT and also cone beam computed tomography (CBCT are the proper modalities to detect these conditions. In the present study, CBCT findings of three cases with maxillary sinus hypoplasia and aplasia are reported.

  6. [Fracture of the maxillary tuberosity in the hemophiliac patient].

    Science.gov (United States)

    Duarte Ronces, M; Hernández Cazares, L; Gutiérrez Romero, M

    1990-11-01

    Fracture of the left maxillary tuberosity during surgical extraction of multiple teeth, involving the maxillary sinus and pterigomaxillary fossa in a male patient with classic hemophilia due to factor VIII deficiency, is reported. The subject was treated by a private dentist and afterwards admitted at the Oral and Maxillofacial Surgery unit of the "20 de N