WorldWideScience

Sample records for assistance enhancing safety

  1. U.S. assistance enhancing safety culture in countries operating Soviet-designed reactors

    International Nuclear Information System (INIS)

    The United States Department of Energy (USDOE) is managing the International Nuclear Safety Program (INSP), which is aimed at providing assistance to enhance safety at commercial nuclear power plants (NPPS) in Russia and Ukraine, as well as Central European countries (CEC). The funding for this program has been provided by the US Agency for International Development (AID). Brookhaven National Laboratory has been assisting DOE in certain portions of this program. The enhancement of safety culture is one of the most important goals of the joint International Nuclear Safety Program. In terms of the INSP, safety culture is comprised of two major components; (1) an environment that is a function of regulations, management sensitivity and structure; and (2) an individual commitment to safety in the day to day execution of activities in terms of thought and accountability. The long term impact of the INSP activities can only be measured by the effectiveness of strengthening safety culture within our partner counties. The strengthening of this culture will manifest in reduced risk of a nuclear accident long after other evidence of the INSP activities has disappeared. One area within the INSP, which has already led to a number of successful specific projects, is under the plant safety upgrade activities. Here, the US and the partner countries jointly identify specific target areas for the INSP efforts. Each identified area has a major component involving safety culture enhancement. With any direct involvement in the particular assistance activities, areas are identified to include a need for training. As technical experts and management from the partner country are assisted in addressing the identified needs, the training programs are provided which will not only address the specific need at hand, but will also teach skills which can be applied to different, but related needs that may exist or develop

  2. Enhancing operational nuclear safety

    International Nuclear Information System (INIS)

    's safety standards and program which provides the safety objective following the 10 fundamental safety principles. The safety requirements defines the functional conditions required for safety and the safety guides provides user-friendly and up-to-date practical guidance representing good/best practices to fulfill the requirements. The IAEA provides safety review services and fields safety review teams upon request of member states for the regulatory, the International Regulatory Review Team (IRRT) and Operational Safety Review Team (OSART) and Peer Review of the Operational and Safety Performance Experience Review (PROSPER). The OSART programme's purpose is to assist member states in enhancing the operational safety of individual nuclear power plants and to promote the continuous development of operational safety within all member states by the dissemination of information on good practice. The OSART Mission Results (OSMIR) database contains the results from 73 OSART missions and 54 follow up visits from 1991 and its continually updated. The Asian Nuclear Safety Network (ANSN) was established to pool and share existing and new technical knowledge and practical experience to further improve the safety of nuclear installation in Asia. In summary, the enhancement of the GNSR is anchored in the recognition that all the states are in the same boat and the increasing importance of sharing and mutual learning, sharing knowledge and experience through regional and global networking. It requires joint and coordinated strategy by all states. The IAEA is willing and ready to support the GNSR through the establishment and application of safety standards, and safety review and advisory services and international instruments. (Author)

  3. ESSAA: Embedded system safety analysis assistant

    Science.gov (United States)

    Wallace, Peter; Holzer, Joseph; Guarro, Sergio; Hyatt, Larry

    1987-01-01

    The Embedded System Safety Analysis Assistant (ESSAA) is a knowledge-based tool that can assist in identifying disaster scenarios. Imbedded software issues hazardous control commands to the surrounding hardware. ESSAA is intended to work from outputs to inputs, as a complement to simulation and verification methods. Rather than treating the software in isolation, it examines the context in which the software is to be deployed. Given a specified disasterous outcome, ESSAA works from a qualitative, abstract model of the complete system to infer sets of environmental conditions and/or failures that could cause a disasterous outcome. The scenarios can then be examined in depth for plausibility using existing techniques.

  4. Enhancing safety culture. Experiences within Nuclear Electric plc. United Kingdom

    International Nuclear Information System (INIS)

    Nuclear electric inherited an enviable safety record over a thirty year period from its predecessor, the Central Electricity Generating Board (CEGB). However , the company has not been complacent, and continues to recognize that there are still many opportunities to improve safety culture within the company. This paper describes two separate aspects of safety culture enhancement that are current within the company. The first is a review of operational experience that has highlighted many organisational characteristics and issues that can affect safety culture. Standard audit and plant evaluation findings were aggregated and then assessed, leading to the identification of common problems and underlying issues. The findings have confirmed that the programme of change within the company, focused around continuous quality improvement concepts, embodies all the necessary elements to address the issues and enhance safety culture if used appropriately. The challenge is now to ensure that each units business planning process adequately addresses the underlying issues. The second part of the paper presents just one example of specific developments at NE's power stations. At hinkley point, there is a strong desire to enhance safety culture at all levels on the station. Various safety awareness raising workshops that have been developed, together with a programme designed to assist the team leaders (first line supervisors) foster an improved safety culture within their teams. The first phase of the programme is coming to completion, and appears to have had considerable effect in raising awareness of the issues amongst team leaders and their line management. It has identified several key issues for the senior management team to address. Methods of providing more detailed practical assistance to the team leaders are being developed to assist the change in attitudes and behaviours required to further enhance the station's safety culture. (author)

  5. Vehicle Safety Enhancement System: Sensing and Communication

    OpenAIRE

    Huihuan Qian; Yongquan Chen; Yuandong Sun; Niansheng Liu; Ning Ding; Yangsheng Xu; Guoqing Xu; Yunjian Tang; Jingyu Yan

    2013-01-01

    With the substantial increase of vehicles on road, driving safety and transportation efficiency have become increasingly concerned focus from drivers, passengers, and governments. Wireless networks constructed by vehicles and infrastructures provide abundant information to share for the sake of both enhanced safety and network efficiency. This paper presents the systematic research to enhance the vehicle safety by wireless communication, in the aspects of information acquisition through vehic...

  6. Suitable footwear for enhanced safety

    CERN Document Server

    2004-01-01

    Safety shoes are the theme of a new safety campaign. Always remember that accidents can happen - even to your feet! When entering hazardous areas such as underground halls, work sites, experiment assembly sites, workshops etc., sandals, ordinary shoes or similar light footwear should not be worn. Whatever the risks to which you may be exposed, always think safety and wear suitable footwear, i.e. safety shoes, which have non-slip soles and steel reinforcements to protect your feet from being crushed, fractured or pierced. Is it serious, Doctor? "Some traumas resulting from foot-related accidents - open fractures for instance - can be quite serious," explains CERN Works Doctor Véronique Fassnacht. "But the most common injuries are sprained ankles sustained during simple falls caused by differences in floor-levels (e.g. false floors). Fractures, bruising, surface wounds or deep wounds caused by objects falling onto the top of the foot are also quite common." ...

  7. Enhancement of nuclear safety culture

    International Nuclear Information System (INIS)

    Throughout the 40-year history of the commercial nuclear power industry, improvements have continually been made in the design of nuclear power plants and the equipment in them. In one sense, we have reached an enviable point -- in most plants, equipment failures have become relatively rare. Yet events continue to occur. Regardless of how much the plants are improved, that equipment is operated by people -- highly motivated, well-trained people -- but people nonetheless. And people occasionally make mistakes. By setting the right climate and by setting high standards, good plant management can reduce the number of mistakes made ? and also reduce their potential consequences. Another way to say this is that the proper safety culture must be established and continually improved upon in our nuclear plants. Safety culture is defined by the International Atomic Energy Agency as 'that assembly of characteristics and attitudes in organizations and individuals which establishes that, as an overriding priority, nuclear plant safety issues receive the attention that, as an overriding priority, nuclear plant safety issues receive the attention warranted by their significance.' In short, we must make safety our top priority

  8. Use of a Web Site to Enhance Criticality Safety Training

    International Nuclear Information System (INIS)

    Currently, a website dedicated to enhancing communication and dissemination of criticality safety information is sponsored by the U.S. Department of Energy (DOE) Nuclear Criticality Safety Program (NCSP). This website was developed as part of the DOE response to the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 97-2, which reflected the need to make criticality safety information available to a wide audience. The website is the focal point for DOE nuclear criticality safety (NCS) activities, resources and references, including hyperlinks to other sites actively involved in the collection and dissemination of criticality safety information. The website is maintained by the Lawrence Livermore National Laboratory (LLNL) under auspices of the NCSP management. One area of the website contains a series of Nuclear Criticality Safety Engineer Training (NCSET) modules. During the past few years, many users worldwide have accessed the NCSET section of the NCSP website and have downloaded the training modules as an aid for their training programs. This trend was remarkable in that it points out a continuing need of the criticality safety community across the globe. It has long been recognized that training of criticality safety professionals is a continuing process involving both knowledge-based training and experience-based operations floor training. As more of the experienced criticality safety professionals reach retirement age, the opportunities for mentoring programs are reduced. It is essential that some method be provided to assist the training of young criticality safety professionals to replenish this limited human expert resource to support on-going and future nuclear operations. The main objective of this paper is to present the features of the NCSP website, including its mission, contents, and most importantly its use for the dissemination of training modules to the criticality safety community. We will discuss lessons learned and several ideas

  9. Use of a Web Site to Enhance Criticality Safety Training

    Energy Technology Data Exchange (ETDEWEB)

    Huang, S T; Morman, J

    2003-08-04

    Currently, a website dedicated to enhancing communication and dissemination of criticality safety information is sponsored by the U.S. Department of Energy (DOE) Nuclear Criticality Safety Program (NCSP). This website was developed as part of the DOE response to the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 97-2, which reflected the need to make criticality safety information available to a wide audience. The website is the focal point for DOE nuclear criticality safety (NCS) activities, resources and references, including hyperlinks to other sites actively involved in the collection and dissemination of criticality safety information. The website is maintained by the Lawrence Livermore National Laboratory (LLNL) under auspices of the NCSP management. One area of the website contains a series of Nuclear Criticality Safety Engineer Training (NCSET) modules. During the past few years, many users worldwide have accessed the NCSET section of the NCSP website and have downloaded the training modules as an aid for their training programs. This trend was remarkable in that it points out a continuing need of the criticality safety community across the globe. It has long been recognized that training of criticality safety professionals is a continuing process involving both knowledge-based training and experience-based operations floor training. As more of the experienced criticality safety professionals reach retirement age, the opportunities for mentoring programs are reduced. It is essential that some method be provided to assist the training of young criticality safety professionals to replenish this limited human expert resource to support on-going and future nuclear operations. The main objective of this paper is to present the features of the NCSP website, including its mission, contents, and most importantly its use for the dissemination of training modules to the criticality safety community. We will discuss lessons learned and several ideas

  10. Modified Fittings Enhance Industrial Safety

    Science.gov (United States)

    2012-01-01

    Kennedy Space Center is not only home to one of the largest buildings in the world - the massive Vehicle Assembly Building - it also hosts a number of one-of-a-kind facilities. The more than 30-mile-long campus has witnessed every launch from the Space Shuttle Launch Pad, as well as many homecomings at the Shuttle Landing Facility. Just as important, the Space Station Processing Facility (SSPF) has seen each element of the International Space Station (ISS) that passes through Kennedy before it goes into orbit. The SSPF is where ISS components are checked, tested, and adjusted before being packed into the Space Shuttle for transport. In an environment like the SSPF - spanning 457,000 square feet of processing areas, operational control rooms, laboratories, logistics areas, and office space - large workstands and equipment used to support the processing of ISS components need to be moved around the facility. One of the devices employed for this task is an air pallet. An air pallet moves on cushions of air instead of wheels. Compressed air inflates the cushions underneath the pallet and is then expelled through exhaust holes. This forms a thin film of air between the cushions and the floor, lifting the platform off the floor and making it easy to move the heavy workstands, equipment, and ISS components. Concerned with the safety of the connections on the pressurized air hoses used for the air pallets, engineers at Kennedy modified an existing commercial cam and groove fitting to control the air supply hose in the event of an accidental release of a pressurized hose. This modification prevented the hose from detaching and, propelled by compressed air, striking workers or equipment. "At the time, these were not available on commercial coupling halves, so NASA made a modification and then put them into use. If a worker were to accidentally try to remove a pressurized hose from the pallet, it no longer rapidly separated, and it safely relieved the pressure," says Paul

  11. Safety culture in nuclear installations. Guidance for the use in enhancement of safety culture

    International Nuclear Information System (INIS)

    This guidance has been developed for use in the IAEA Safety Culture Services, which provides support to Member States in their efforts to develop a sound safety culture of their organizations. It will be of particular use in seminars and training workshops that are part of these services. Much of the information in this publication reflects the approach the IAEA has adopted to assist nuclear organizations in Member States in improving their safety culture. This guidance covers topics such as: what is culture, and in particular what is safety culture; what are the stages of development of safety culture, and how you can assess its development using employee surveys; what practices can be used to develop safety culture, and what indicators will help monitor progress. The symptoms of a weakening safety culture are described, as well as the lessons learned from organizations who have experienced safety culture problems. This guide also contains information on how to undertake the process of transforming the existing safety culture, and develop a learning culture in an organization that is based on continuous improvement. The relationship between quality and safety is discussed. The safety culture services offered by the IAEA are also described. The IAEA perspective of safety culture has expanded with time as its understanding of the complexities of the concept developed. The concept of safety culture was first introduced by the International Nuclear Safety Advisory Group formed by the IAEA. In their report (INSAG-4, 1991) they maintained that the establishment of a safety culture within an organization is one of the fundamental management principles necessary for the safe operation of a nuclear facility. The definition recognized that safety culture is both structural and attitudinal in nature and relates to the organization and its style, as well as to attitudes, approaches and the commitment of individuals at all levels in the organization. In the framework of the

  12. Minimally assistive robot training for proprioception enhancement.

    Science.gov (United States)

    Casadio, Maura; Morasso, Pietro; Sanguineti, Vittorio; Giannoni, Psiche

    2009-04-01

    In stroke survivors, motor impairment is frequently associated with degraded proprioceptive and/or somatosensory functions. Here we address the question of how to use robots to improve proprioception in these patients. We used an 'assist-as-needed' protocol, in which robot assistance was kept to a minimum and was continuously adjusted during exercise. To specifically train proprioceptive functions, we alternated blocks of trials with and without vision. A total of nine chronic stroke survivors participated in the study, which consisted of a total of ten 1-h exercise sessions. We used a linear mixed-effects statistical model to account for the effects of exercise, vision and the degree of assistance on the overall performance, and to capture both the systematic effects and the individual variations. Although there was not always a complete recovery of autonomous movements, all subjects exhibited an increased amount of voluntary control. Moreover, training with closed eyes appeared to be beneficial for patients with abnormal proprioception. Our results indicate that training by alternating vision and no-vision blocks may improve the ability to use proprioception as well as the ability to integrate it with vision. We suggest that the approach may be useful in the more general case of motor skill acquisition, in which enhancing proprioception may improve the ability to physically interact with the external world. PMID:19139867

  13. Minimally assistive robot training for proprioception enhancement.

    Science.gov (United States)

    Casadio, Maura; Morasso, Pietro; Sanguineti, Vittorio; Giannoni, Psiche

    2009-04-01

    In stroke survivors, motor impairment is frequently associated with degraded proprioceptive and/or somatosensory functions. Here we address the question of how to use robots to improve proprioception in these patients. We used an 'assist-as-needed' protocol, in which robot assistance was kept to a minimum and was continuously adjusted during exercise. To specifically train proprioceptive functions, we alternated blocks of trials with and without vision. A total of nine chronic stroke survivors participated in the study, which consisted of a total of ten 1-h exercise sessions. We used a linear mixed-effects statistical model to account for the effects of exercise, vision and the degree of assistance on the overall performance, and to capture both the systematic effects and the individual variations. Although there was not always a complete recovery of autonomous movements, all subjects exhibited an increased amount of voluntary control. Moreover, training with closed eyes appeared to be beneficial for patients with abnormal proprioception. Our results indicate that training by alternating vision and no-vision blocks may improve the ability to use proprioception as well as the ability to integrate it with vision. We suggest that the approach may be useful in the more general case of motor skill acquisition, in which enhancing proprioception may improve the ability to physically interact with the external world.

  14. Effective corrective actions to enhance operational safety of nuclear installations

    International Nuclear Information System (INIS)

    The safe operation of nuclear power plants around the world and the prevention of incidents in these installations remain key concerns for the nuclear community. In this connection the feedback of operating experience plays a major role: every nuclear plant operator needs to have a system in place to identify and feed back the lessons learned from operating experience and to implement effective corrective actions to prevent safety events from reoccurring. An effective operating experience programme also includes a proactive approach that is aimed at preventing the first-time occurrence of safety events. In April 2003, the IAEA issued the PROSPER guidelines for nuclear installations to strengthen and enhance their own operating experience process and for self-assessment on the effectiveness of the feedback process. Subsequently, in the course of the Operational Safety Review Teams missions conducted by the IAEA that focused on the operational safety practices of nuclear power plants, the IAEA enhanced the review of the operating experience in nuclear power plants by implementing a new module that is derived from these guidelines. In order to highlight the effective implementation of the operating experience programme and to provide practical assistance in this area, the IAEA organized workshops and conferences to discuss recent trends in operating experience. The IAEA also performed assistance and review missions at plants and corporate organizations. The IAEA is further developing advice and assistance on operating experience feedback programmes and is reporting on good practices. The present publication is the outcome of two years of coordinated effort involving the participation of experts of nuclear organizations in several Member States. It provides information and good practices for successfully establishing an effective corrective actions programme. This publication forms part of a series that develops the principles set forth in these guidelines

  15. 78 FR 53790 - Public Forum-Safety Culture: Enhancing Transportation Safety

    Science.gov (United States)

    2013-08-30

    ... Culture; Organizational Leadership Perspectives on Safety Culture; Safety Culture Management and Oversight... effective safety cultures within their industries. There will also be a review of some recent organizational... SAFETY BOARD Public Forum--Safety Culture: Enhancing Transportation Safety On Tuesday and...

  16. Safety Culture Enhancement Project. Final Report. A Field Study on Approaches to Enhancement of Safety Culture

    International Nuclear Information System (INIS)

    This report documents a study with the objective of enhancing safety culture in the Swedish nuclear power industry. A primary objective of this study was to ensure that the latest thinking on human factors principles was being recognised and applied by nuclear power operators as a means of ensuring optimal safety performance. The initial phase of the project was conducted as a pilot study, involving the senior management group at one Swedish nuclear power-producing site. The pilot study enabled the project methodology to be validated after which it was repeated at other Swedish nuclear power industry sites, providing a broad-ranging analysis of opportunities across the industry to enhance safety culture. The introduction to this report contains an overview of safety culture, explains the background to the project and sets out the project rationale and objectives. The methodology used for understanding and analysing the important safety culture issues at each nuclear power site is then described. This section begins with a summary of the processes used in the information gathering and data analysis stage. The six components of the Management Workshops conducted at each site are then described. These workshops used a series of presentations, interactive events and group exercises to: (a) provide feedback to site managers on the safety culture and safety leadership issues identified at their site, and (b) stimulate further safety thinking and provide 'take-away' information and leadership strategies that could be applied to promote safety culture improvements. Section 3, project Findings, contains the main observations and output from the project. These include: - a brief overview of aspects of the local industry operating context that impinge on safety culture; - a summary of strengths or positive attributes observed within the safety culture of the Swedish nuclear industry; - a set of identified opportunities for further improvement; - the aggregated results of the

  17. Safety Culture Enhancement Project. Final Report. A Field Study on Approaches to Enhancement of Safety Culture

    Energy Technology Data Exchange (ETDEWEB)

    Lowe, Andrew; Hayward, Brent (Dedale Asia Pacific, Albert Park VIC 3206 (Australia))

    2006-08-15

    This report documents a study with the objective of enhancing safety culture in the Swedish nuclear power industry. A primary objective of this study was to ensure that the latest thinking on human factors principles was being recognised and applied by nuclear power operators as a means of ensuring optimal safety performance. The initial phase of the project was conducted as a pilot study, involving the senior management group at one Swedish nuclear power-producing site. The pilot study enabled the project methodology to be validated after which it was repeated at other Swedish nuclear power industry sites, providing a broad-ranging analysis of opportunities across the industry to enhance safety culture. The introduction to this report contains an overview of safety culture, explains the background to the project and sets out the project rationale and objectives. The methodology used for understanding and analysing the important safety culture issues at each nuclear power site is then described. This section begins with a summary of the processes used in the information gathering and data analysis stage. The six components of the Management Workshops conducted at each site are then described. These workshops used a series of presentations, interactive events and group exercises to: (a) provide feedback to site managers on the safety culture and safety leadership issues identified at their site, and (b) stimulate further safety thinking and provide 'take-away' information and leadership strategies that could be applied to promote safety culture improvements. Section 3, project Findings, contains the main observations and output from the project. These include: - a brief overview of aspects of the local industry operating context that impinge on safety culture; - a summary of strengths or positive attributes observed within the safety culture of the Swedish nuclear industry; - a set of identified opportunities for further improvement; - the aggregated

  18. Sociodrama approach for enhancing nuclear safety

    Energy Technology Data Exchange (ETDEWEB)

    Choi, K. S.; Kim, C. B.; Ha, Y. H. [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of)

    2004-07-01

    A role playing or sociodrama has been experimentally conducted among residents from 4 NPP sites in Korea and KINS employees as a psychological approach for enhancing nuclear safety and improving public communication and public confidence in regulator in Dec. 2004. In this paper, the results were analyzed and presented and future plan and area of further study were suggested. This socio-psychological approach can be used as a new communication method for improving mutual understanding between residents and NPP operators at sites. It can be also used to solve conflicts among stakeholders and interest groups in nuclear industry.

  19. CANDU 9 safety enhancements and licensability

    International Nuclear Information System (INIS)

    The CANDU 9 design has followed the evolutionary product development approach that has characterized the CANDU family of nuclear power plants. In addition to utilizing proven equipment and systems from operating stations, the CANDU 9 design has looked ahead to incorporate design and safety enhancements necessary to meet evolving utility and regulatory requirements both in Canada and overseas. To demonstrate licensability in Canada, and to assure overseas customers that the design had independent regulatory review in the country of origin, the pre-project Basic Engineering Program included an extensive two year formal review by the Canadian regulatory authority, the Atomic Energy Control Board (AECB). Documentation submitted for this licensing review included the licensing basis, safety requirements and safety analysis necessary to demonstrate compliance with regulations as well as to assess system design and performance. The licensing review was successfully completed in 1997 January. In addition, to facilitate licensability in Korea, CANDU 9 incorporates feedback from the application of Korean licensing requirements to the CANDU 6 reactors at Wolsong site. (author)

  20. Electronuclear's safety culture assessment and enhancement program

    International Nuclear Information System (INIS)

    The present paper describes the Eletronuclear's safety culture assessment and enhancement program. The program was launched by the company's top management one year after the creation of Eletronuclear in 1997, from the merging of two companies with different organizational cultures, the design and engineering company Nuclen and the nuclear directorate of the Utility Furnas, Operator of the Angra1 NPP. The program consisted of an assessment performed internally in 1999 with the support and advice of the IAEA. This assessment, performed with the help of a survey, pooled about 80% of the company's employees. The overall result of the assessment was that a satisfactory level of safety culture existed; however, a number of points with a considerable margin for improvement were also identified. These points were mostly related with behavioural matters such as motivation, stress in the workplace, view of mistakes, handling of conflicts, and last but not least a view by a considerable number of employees that a conflict between safety and production might exist. An Action Plan was established by the company managers to tackle these weak points. This Plan was issued as company guideline by the company's Directorate. The subsequent step was to detail and implement the different actions of the Plan, which is the phase that we are at present. In the detailing of the Action Plan, special care was taken to sum up efforts, avoiding duplication of work or competition with already existing programs. In this process it was identified that the company had a considerable number of initiatives directly related to organizational and safety culture improvement, already operational. These initiatives have been integrated in the detailed Action Plan. A new assessment, for checking the effectiveness of the undertaken actions, is planned for 2003. (author)

  1. Safety Culture Enhancement Project. Final Report. A Field Study on Approaches to Enhancement of Safety Culture

    Energy Technology Data Exchange (ETDEWEB)

    Lowe, Andrew; Hayward, Brent (Dedale Asia Pacific, Albert Park VIC 3206 (Australia))

    2006-08-15

    This report documents a study with the objective of enhancing safety culture in the Swedish nuclear power industry. A primary objective of this study was to ensure that the latest thinking on human factors principles was being recognised and applied by nuclear power operators as a means of ensuring optimal safety performance. The initial phase of the project was conducted as a pilot study, involving the senior management group at one Swedish nuclear power-producing site. The pilot study enabled the project methodology to be validated after which it was repeated at other Swedish nuclear power industry sites, providing a broad-ranging analysis of opportunities across the industry to enhance safety culture. The introduction to this report contains an overview of safety culture, explains the background to the project and sets out the project rationale and objectives. The methodology used for understanding and analysing the important safety culture issues at each nuclear power site is then described. This section begins with a summary of the processes used in the information gathering and data analysis stage. The six components of the Management Workshops conducted at each site are then described. These workshops used a series of presentations, interactive events and group exercises to: (a) provide feedback to site managers on the safety culture and safety leadership issues identified at their site, and (b) stimulate further safety thinking and provide 'take-away' information and leadership strategies that could be applied to promote safety culture improvements. Section 3, project Findings, contains the main observations and output from the project. These include: - a brief overview of aspects of the local industry operating context that impinge on safety culture; - a summary of strengths or positive attributes observed within the safety culture of the Swedish nuclear industry; - a set of identified opportunities for further improvement; - the aggregated

  2. Enhancing Transfusion Safety: Nurse’s Role

    Directory of Open Access Journals (Sweden)

    Kyriazi Vasiliki

    2011-01-01

    Full Text Available Background: Despite strict clinical measures, there are distinct steps in transfusion process which require acute attention.The nurse is responsible for insuring that the right unit is administered to the right patient. Knowledge of risks is essential toadminister and monitor transfusions safely.Aim: This study summarizes the available data concerning transfusion adverse events and provides theoretical and technicalaspects for improving transfusion practice.Methodology: A systematic review in PubMed, MedLine and MDConsult database was conducted. The research limitsincluded English texts, referring to transfusion risks and technological means aiming at transfusion safety.Results: Blood transfusion is a medical intervention that saves lives and improves the quality of life. The regulations forensuring the availability and assuring the quality of the blood component cannot avoid transfusion errors, placing patients atrisk. Most frequent errors are attributed to practitioners involved in the clinical transfusion process. Based on reports toSerious Hazards of Transfusion (SHOT the risk of transfusion error is estimated at 1:16,500. Over the last years severalcommittees have recommended guidance for enhancing the safety of blood ordering and administration. Moreover, newtechnology like barcode on patient wristband manages to improve the performance in each step.Conclusion: Safe transfusion process depends on a series of linked processes and nurses should take specific measuresreferring to pre- and post-transfusion stage. Technological innovations could help patients in need of transfusion therapy.

  3. TSO assistance towards the improvement of nuclear safety in Lithuania: achievements and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Butcher, P. [Serco Assurance, Winfrith, Dorchester, Dorset (United Kingdom); Bystedt, P. [Swedish International Project, Nuclear Safety (SIP), Stockholm (Sweden); Chouha [CEA Fontenay-aux-Roses, 92 (France). Inst. de Protection et de Surete Nucleaire; Uspuras, E. [Lithuanian Energy Institute (LEI), Kaunas (Lithuania); Weber, J.P. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, Garching (Germany); Zilys, K. [State Nuclear Power Safety Inspectorate (VATESI), Vilnius (Lithuania)

    2001-07-01

    This paper explores the improvements that have taken place at INPP (Ignalina nuclear power plant) in both the engineering and operational aspects of nuclear safety, discussing as example some areas where there has been a large involvement of international experts. The development of the Lithuanian Nuclear Regulatory Authority VATESI, and also the technical support organisations for both the regulator and the NPP are discussed. In each of these sections the paper describes some of the successes and also the areas where there have been some problems. Many of the problems have been resolved but challenges remain for the future. The paper only deals with the assistance towards enhancing the safety of the NPP up to the time of its closure. Regulation of decommissioning is an important area for the future and is receiving urgent attention and active planning at the present time. (authors)

  4. Enhancing nuclear safety by strengthening regulatory competencies

    International Nuclear Information System (INIS)

    In order to support the international obligations of the Russian Federation on NPP construction in several countries (Belarus, Turkey, Iran, Vietnam, Bangladesh,...) that are new users of nuclear energy, the Russian Regulatory Body (Rostechnadzor) with the support of TSO - Federal State Unitary Enterprise VO 'Safety' (FSUE VO Safety) has developed a comprehensive modular program for training the specialists of the nuclear and radiation safety authorities of these countries. The program main task is the knowledge transfer in the area of nuclear and radiation safety regulations. The lectures of the Program cover the full set of regulatory competencies in compliance with the corresponding IAEA safety standards and they comply with the objectives of the IAEA 'Strategic Approach to Education and Training in Nuclear Safety 2013 - 2022'

  5. IAEA Assistance in Helping Member States Develop Effectively Independent and Robust Regulators for Nuclear Installation Safety

    International Nuclear Information System (INIS)

    Full text: The International Conference on Topical Issues in Nuclear Installation Safety will be focused on the exchange of information on the latest thinking and advances in the implementation of the concept of Defence-in-Depth (DID) in nuclear installations, and the associated challenges. The focus will be on operating nuclear installations, including nuclear power plants, research reactors and fuel cycle facilities, and on how lessons learned from operating experience and recent events (e.g. the Fukushima Daiichi accident) are used to enhance safety. The implementation of DID covers a number of elements that are directly related to the different states and phases of a nuclear facility. This presentation will discuss the importance of the regulatory body in its oversight role as a cross-cutting element of DID in helping to assure the safety of nuclear installations. Taking note of the numerous challenges in developing an effectively independent and robust regulatory body, the presentation will describe how the IAEA assists Member States in their development of the appropriate regulatory infrastructure and necessary capacity to carry out their regulatory responsibilities – consistent with the IAEA Safety Standards. The presentation will describe the importance of the self-assessment process which serves as a starting point for helping Member States gain an understanding of what support they need and when the support should be provided as they develop into a competent regulatory authority. The presentation will discuss recent improvements in the self-assessment process and related IAEA services in this regard. Once regulatory bodies are established, it is essential that they seek continuous improvement. In this regard, the presentation will describe the IAEA’s assistance provided through the Integrated Regulatory Review Service (IRRS) and recent activities to improve the IRRS, consistent with the IAEA’s Action Plan on Nuclear Safety. (author)

  6. The safety of electrically assisted bicycles compared to classic bicycles.

    Science.gov (United States)

    Schepers, J P; Fishman, E; den Hertog, P; Wolt, K Klein; Schwab, A L

    2014-12-01

    Use of electrically assisted bicycles with a maximum speed of 25 km/h is rapidly increasing. This growth has been particularly rapid in the Netherlands, yet very little research has been conducted to assess the road safety implications. This case-control study compares the likelihood of crashes for which treatment at an emergency department is needed and injury consequences for electric bicycles to classic bicycles in the Netherlands among users of 16 years and older. Data were gathered through a survey of victims treated at emergency departments. Additionally, a survey of cyclists without any known crash experience, drawn from a panel of the Dutch population acted as a control sample. Logistic regression analysis is used to compare the risk of crashes with electric and classical bicycles requiring treatment at an emergency department. Among the victims treated at an emergency department we compared those being hospitalized to those being send home after the treatment at the emergency department to compare the injury consequences between electric and classical bicycle victims. The results suggest that, after controlling for age, gender and amount of bicycle use, electric bicycle users are more likely to be involved in a crash that requires treatment at an emergency department due to a crash. Crashes with electric bicycles are about equally severe as crashes with classic bicycles. We advise further research to develop policies to minimize the risk and maximize the health benefits for users of electric bicycles.

  7. Safety enhancement solutions Laguna Verde NPP

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-10-15

    After the event happened in the nuclear power plant of Fukushima (Japan) proposals are carried out to improve the safety systems in the nuclear power plant of Laguna Verde (Mexico), from the application of the recommendations of the US NRC, until the considerations for the renovation of the operation license. (Author)

  8. Safety enhancement during refurbishing of research reactor Cirus

    International Nuclear Information System (INIS)

    The plan to refurbish Cirus, after 37 years of operation, was finalized after detailed ageing studies of all systems and equipment and extensive evaluations pertaining specifically to the jobs requiring core unloading and extended outage. Additional jobs scheduled were towards reduction in man-rem, safety enhancement and retrofitting of technology upgrades. All details of the refurbishing plan were deliberated in appropriate safety committees and a consolidated list of jobs was prepared before the commencement of extended outage. This paper discusses the various safety enhancement issues which have been addressed as a part of the overall refurbishing plan. (author)

  9. Enhancing Safety at Airline Operations Control Centre

    Directory of Open Access Journals (Sweden)

    Lukáš Řasa

    2015-04-01

    Full Text Available In recent years a new term of Safety Management System (SMS has been introduced into aviation legislation. This system is being adopted by airline operators. One of the groundbased actors of everyday operations is Operations Control Centre (OCC. The goal of this article has been to identify and assess risks and dangers which occur at OCC and create a template for OCC implementation into SMS.

  10. Physician attitudes towards pharmacological cognitive enhancement: safety concerns are paramount.

    Directory of Open Access Journals (Sweden)

    Opeyemi C Banjo

    Full Text Available The ethical dimensions of pharmacological cognitive enhancement have been widely discussed in academic circles and the popular media, but missing from the conversation have been the perspectives of physicians - key decision makers in the adoption of new technologies into medical practice. We queried primary care physicians in major urban centers in Canada and the United States with the aim of understanding their attitudes towards cognitive enhancement. Our primary hypothesis was that physicians would be more comfortable prescribing cognitive enhancers to older patients than to young adults. Physicians were presented with a hypothetical pharmaceutical cognitive enhancer that had been approved by the regulatory authorities for use in healthy adults, and was characterized as being safe, effective, and without significant adverse side effects. Respondents overwhelmingly reported increasing comfort with prescribing cognitive enhancers as the patient age increased from 25 to 65. When asked about their comfort with prescribing extant drugs that might be considered enhancements (sildenafil, modafinil, and methylphenidate or our hypothetical cognitive enhancer to a normal, healthy 40 year old, physicians were more comfortable prescribing sildenafil than any of the other three agents. When queried as to the reasons they answered as they did, the most prominent concerns physicians expressed were issues of safety that were not offset by the benefit afforded the individual, even in the face of explicit safety claims. Moreover, many physicians indicated that they viewed safety claims with considerable skepticism. It has become routine for safety to be raised and summarily dismissed as an issue in the debate over pharmacological cognitive enhancement; the observation that physicians were so skeptical in the face of explicit safety claims suggests that such a conclusion may be premature. Thus, physician attitudes suggest that greater weight be placed upon the

  11. Food Assistance: How Strong Is the Safety Net?

    OpenAIRE

    LeBlanc, Michael; Lin, Biing-Hwan; Smallwood, David M.

    2006-01-01

    Food assistance programs, particularly the Food Stamp Program, increase food spending and household income. In 2004, adding food stamp benefits to recipients’ incomes raised 9 percent of recipients out of poverty. Nutritional effects of food assistance programs are uncertain.

  12. Safety Enhancements for TRU Waste Handling - 12258

    Energy Technology Data Exchange (ETDEWEB)

    Cannon, Curt N. [Perma-Fix Northwest Richland, Inc., Richland, WA 99354 (United States)

    2012-07-01

    For years, proper Health Physics practices and 'As Low As Reasonably Achievable' (ALARA) principles have fostered the use of glove boxes or other methods of handling (without direct contact) high activities of radioactive material. The physical limitations of using glove boxes on certain containers have resulted in high-activity wastes being held in storage awaiting a path forward. Highly contaminated glove boxes and other remote handling equipment no longer in use have also been added to the growing list of items held for storage with no efficient method of preparation for proper disposal without creating exposure risks to personnel. This is especially true for wastes containing alpha-emitting radionuclides such as Plutonium and Americium that pose significant health risks to personnel if these Transuranic (TRU) wastes are not controlled effectively. Like any good safety program or root cause investigation PFNW has found that the identification of the cause of a negative change, if stopped, can result in a near miss and lessons learned. If this is done in the world of safety, it is considered a success story and is to be shared with others to protect the workers. PFNW believes that the tools, equipment and resources have improved over the past number of years but that the use of them has not progressed at the same rate. If we use our tools to timely identify the effect on the work environment and immediately following or possibly even simultaneously identify the cause or some of the causal factors, we may have the ability to continue to work rather than succumb to the start and stop-work mentality trap that is not beneficial in waste minimization, production efficiency or ALARA. (authors)

  13. Leadership and Safety Management: Regulatory Initiatives for Enhancing Nuclear Safety in the Republic of Korea

    International Nuclear Information System (INIS)

    Since the construction of the first nuclear power plant (NPP) in the Republic of Korea in 1978, a high level of nuclear safety has continued to be maintained. This has been the important basis on which the continuous construction of NPPs has been possible in the country. To date, regulatory initiatives, leaderships and strategies adopting well harmonized regulatory systems and practices of advanced countries have contributed to improving the effectiveness and efficiency of safety regulation and further enhancing nuclear safety. The outcomes have resulted in a high level of safety and performance of Korean NPPs, attributing largely to the safety promotion policy. Recently, with the support of the Korean Ministry of Education, Science and Technology (MEST), the Korea Institute of Nuclear Safety (KINS) established the International Nuclear Safety School and created a Nuclear Safety Master's Degree Programme. Further, it developed multilateral and bilateral cooperation with other agencies to promote global nuclear safety, with the aim of providing knowledge and training to new entrant countries in establishing the safety infrastructure necessary for ensuring an acceptable level of nuclear safety. (author)

  14. Enhancing Safety Performance of Research Reactors at Trombay

    International Nuclear Information System (INIS)

    Based on various national requirements of basic research, material testing, isotope production, criticality experiments and research related to future power reactor program, Indian research reactor program encompasses a variety of reactors from simple pool type reactor Apsara to complex 100 MW reactor like Dhruva. To meet the varied and complex safety requirements of research reactors, a strong safety management system has also been evolved and nurtured. With over 150 reactor years of operating feedback, wealth of experience has been gained and safety enhancement has been kept as a continuously evolving process at Trombay. The 100 MWth research reactor Dhruva has now completed more than two and half decades of operation. Based on a systematic In-Service Inspection (ISI) program, structured system performance monitoring and review and Periodic Safety Review (PSR) certain incipient failures in the system could be noted and corrected in time. Based on these reviews, certain mid-term safety upgrades in various systems of Dhruva were carried out. This paper will provide an overview of overall safety enhancement of research reactors, through refurbishment, and engineering changes. (author)

  15. Knowledge management and networking for enhancing nuclear safety

    International Nuclear Information System (INIS)

    Striving for innovative solutions to enhance efficiency of programme delivery and a wider outreach of its nuclear safety activities, the International Atomic Energy Agency (IAEA) has developed an Integrated Safety Approach as a platform for linking its safety related statutory functions and its many associated activities. The approach recognizes the vital importance of effective management of the knowledge base and builds on the integration between the IAEA's safety standards and all aspects of the provision for their application, including peer reviews and technical meetings to share lessons learned. The IAEA is using knowledge management techniques to develop process flows, map safety knowledge and to promote knowledge sharing. The first practical application was the establishment of a knowledge base related to safety aspects of ageing and long-term operation of nuclear power plants. The IAEA is also promoting and facilitating the establishment of regional nuclear and radiation safety networks to preserve existing knowledge and expertise as well as to strengthen sharing and creation of new knowledge in these fields. Prominent examples are the Asian Nuclear Safety Network established in the frame of the IAEA's Programme on the Safety of Nuclear Installations in South East Asia, Pacific and Far East Countries, and the Ibero-American Radiation Safety Network in the frame of the Ibero-American Forum of Nuclear Regulators. Results to date are most encouraging and suggest that this pioneer work should be extended to other regions and eventually to a global nuclear safety network. Responsive to the need of Member States, the IAEA Secretariat has prepared and made available a large number of up-to-date training packages in nuclear, radiation, transport and waste safety, using IAEA safety standards as a basis. It is also providing instruction to trainers in Member States on the use of these modules. This ensures that the material is properly used and that the IAEA

  16. Knowledge management and networking for enhancing nuclear safety

    International Nuclear Information System (INIS)

    Striving for innovative solutions to enhance the efficiency of programme delivery and a wider outreach of its nuclear safety activities, the IAEA has developed an Integrated Safety Approach as a platform for linking its safety related statutory functions and its many associated activities. The approach recognizes the vital importance of the effective management of the knowledge base and builds on the integration between the IAEA's Safety Standards and all aspects of the provision for their application, including peer reviews and technical meetings to share lessons learned. The IAEA is using knowledge management techniques to develop process flows, map safety knowledge and promote knowledge sharing. The first practical application was the establishment of a knowledge base related to safety aspects of ageing and the long term operation of nuclear power plants. The IAEA is also promoting and facilitating the establishment of regional nuclear and radiation safety networks to preserve existing knowledge and expertise, as well as to strengthen the sharing and creation of new knowledge in these fields. Prominent examples are the Asian Nuclear Safety Network established in the frame of the IAEA's Programme on the Safety of Nuclear Installations in South East Asia, Pacific and Far East Countries, and the Ibero-American Radiation Safety Network in the frame of the Ibero-American Forum of Nuclear Regulators. Results to date are most encouraging and suggest that this pioneering work should be extended to other regions and eventually to a global nuclear safety network. Responsive to the needs of Member States, the IAEA Secretariat has prepared and made available a large number of up to date training packages in nuclear, radiation, transport and waste safety, using IAEA Safety Standards as a basis. It is also providing instruction to trainers in Member States on the use of these modules. This ensures that the material is properly used and that the IAEA receives feedback so that

  17. 78 FR 3311 - Safety Enhancements, Certification of Airports

    Science.gov (United States)

    2013-01-16

    ...) on Safety Enhancements Part 139, Certification of Airports (76 FR 5510). In the NPRM, the FAA... period until May 13, 2011, (76 FR 20570) because we learned that a number of airport operators were not... again reopened the comment period until July 5, 2011, (76 FR 32105) because several industry...

  18. Knowledge management and networking for enhancing nuclear safety

    International Nuclear Information System (INIS)

    Full text: Striving for innovative solutions to enhance efficiency of programme delivery and a wider outreach of its nuclear safety activities, the IAEA has developed an Integrated Safety Approach as a platform for linking its safety related statutory functions and its many related activities. The approach recognizes the vital importance of effective management of the knowledge base and builds on the integration between the Agency's safety standards and all aspects of the provision for their application, including peer reviews and technical meetings to share lessons learned. The IAEA is using knowledge management techniques to develop process flows, map safety knowledge and to promote knowledge sharing. The first practical application was the establishment of a knowledge base related to ageing and long-term operation of nuclear power plants. The IAEA is also promoting and facilitating the establishment of regional nuclear and radiation safety networks to preserve existing knowledge and expertise as well as to strengthen sharing and creation of new knowledge in these fields. Prominent examples are the Asian Nuclear Safety Network established in the frame of the Agency's Programme on the Safety of Nuclear Installations in South East Asia, Pacific and Far East Countries, and the Ibero-American Radiation Safety Network in the frame of the Ibero-American Forum of Nuclear Regulators. Results to date are most encouraging and suggest that this pioneer work should be extended to other regions and eventually to a global safety network. Responsive to the need of Member States, the IAEA Secretariat has prepared and made available a large number of up-to-date training packages in nuclear, radiation, transport and waste safety, using the Agency's safety standards as a basis. It has also provided instruction to trainers in Member States on the use of these modules. This ensures that the material is properly used and that the Agency receives feedback so that training services and

  19. Does assisted driving behavior lead to safety-critical encounters with unequipped vehicles' drivers?

    Science.gov (United States)

    Preuk, Katharina; Stemmler, Eric; Schießl, Caroline; Jipp, Meike

    2016-10-01

    With Intelligent Transport Systems (e.g., traffic light assistance systems) assisted drivers are able to show driving behavior in anticipation of upcoming traffic situations. In the years to come, the penetration rate of such systems will be low. Therefore, the majority of vehicles will not be equipped with these systems. Unequipped vehicles' drivers may not expect the driving behavior of assisted drivers. However, drivers' predictions and expectations can play a significant role in their reaction times. Thus, safety issues could arise when unequipped vehicles' drivers encounter driving behavior of assisted drivers. This is why we tested how unequipped vehicles' drivers (N=60) interpreted and reacted to the driving behavior of an assisted driver. We used a multi-driver simulator with three drivers. The three drivers were driving in a line. The lead driver in the line was a confederate who was followed by two unequipped vehicles' drivers. We varied the equipment of the confederate with an Intelligent Transport System: The confederate was equipped either with or without a traffic light assistance system. The traffic light assistance system provided a start-up maneuver before a light turned green. Therefore, the assisted confederate seemed to show unusual deceleration behavior by coming to a halt at an unusual distance from the stop line at the red traffic light. The unusual distance was varied as we tested a moderate (4m distance from the stop line) and an extreme (10m distance from the stop line) parameterization of the system. Our results showed that the extreme parametrization resulted in shorter minimal time-to-collision of the unequipped vehicles' drivers. One rear-end crash was observed. These results provided initial evidence that safety issues can arise when unequipped vehicles' drivers encounter assisted driving behavior. We recommend that future research identifies counteractions to prevent these safety issues. Moreover, we recommend that system developers

  20. Enhancing Assisted Living Technology with Extended Visual Memory

    Directory of Open Access Journals (Sweden)

    Joo-Hwee Lim

    2011-05-01

    Full Text Available Human vision and memory are powerful cognitive faculties by which we understand the world. However, they are imperfect and further, subject to deterioration with age. We propose a cognitive-inspired computational model, Extended Visual Memory (EVM, within the Computer-Aided Vision (CAV framework, to assist human in vision-related tasks. We exploit wearable sensors such as cameras, GPS and ambient computing facilities to complement a user's vision and memory functions by answering four types of queries central to visual activities, namely, Retrieval, Understanding, Navigation and Search. Learning of EVM relies on both frequency-based and attention-driven mechanisms to store view-based visual fragments (VF, which are abstracted into high-level visual schemas (VS, both in the visual long-term memory. During inference, the visual short-term memory plays a key role in visual similarity computation between input (or its schematic representation and VF, exemplified from VS when necessary. We present an assisted living scenario, termed EViMAL (Extended Visual Memory for Assisted Living, targeted at mild dementia patients to provide novel functions such as hazard-warning, visual reminder, object look-up and event review. We envisage EVM having the potential benefits in alleviating memory loss, improving recall precision and enhancing memory capacity through external support.

  1. Upgraded reactor systems for enhanced safety at TRIGA-INR

    International Nuclear Information System (INIS)

    After almost three decades of operation of stationary TRIGA 14MW with systems provided and installed at reactor first start-up, it appeared obvious that an extended modernization program is required, both for enhancing the nuclear safety and to expand the facility lifetime. A first step has been achieved through complete HEU to LEU core conversion, meaning also core refuelling possibility for the future. Systems that have been subjected to the upgrading program are: control rods, radiation monitoring, data acquisition and processing, ventilation, irradiation devices, and above all, the outstanding modernization of the I and C system, including a brand new reactor control desk. Taking into account own and research reactors community operation experience, IAEA guides and recommendations, the basic requirement for the Instrumentation and Control System is the separation between safety and operation components, in order to decrease human error consequences and avoid common cause failures. Modernization did not cover any sensor replacement, but preserve the present scram logic and conditions (as given and approved in the Safety Report and Licensed Limits and Conditions) The entire modernization program is performed according to QA system. Out of intrinsic nuclear safety enhancement, enhanced population and environment protection is a concern and an expected result of the program. Upgrading the overall performances of the reactor and extending its operational lifetime, the Reactor Department of Institute will be able to perform competitive irradiation tests for nuclear fuel and materials, and to continue to develop nuclear investigation techniques or isotope production. (author)

  2. RFID authentication protocol to enhance patient medication safety.

    Science.gov (United States)

    Kaul, Sonam Devgan; Awasthi, Amit K

    2013-12-01

    Medication errors can cause substantial harm to patients. Automated patient medication system with RFID technology is purposely used to reduce the medication error, to improve the patient safety, to provide personalized patient medication and identification and also to provide counterfeit protection to the patients. In order to enhance medication safety for patients we propose a new dynamic ID based lightweight RFID authentication protocol. Due to low storage capacity and limited computational and communicational capacity of tags, only pseudo random number generator function, one way hash function and bitwise Xor operation are used in our authentication protocol. The proposed protocol is practical, secure and efficient for health care domain.

  3. Special studies and analyses for the Assistant Secretary for Policy, Safety, and Environment. Final report

    International Nuclear Information System (INIS)

    The report identifies major tasks accomplished, details plans for the orderly completion of all work in process, and provides a complete listing of deliverables (reports, briefings, letters, etc.) provided under the contract. Purpose of this contract was to provide environmental studies, analytical planning, evaluation, and other technical assistance and support to the DOE Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness (EP) and designated EP offices and divisions

  4. Criticality safety enhancements for SCALE 6.2 and beyond

    Energy Technology Data Exchange (ETDEWEB)

    Rearden, Bradley T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Bekar, Kursat B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Celik, Cihangir [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Clarno, Kevin T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dunn, Michael E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hart, Shane W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ibrahim, Ahmad M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Johnson, Seth R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Langley, Brandon R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lefebvre, Jordan P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lefebvre, Robert A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Marshall, William J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mertyurek, Ugur [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Mueller, Don [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Peplow, Douglas E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Perfetti, Christopher M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Petrie Jr, Lester M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Thompson, Adam B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wiarda, Dorothea [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wieselquist, William A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Mark L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-01-01

    SCALE is a widely used suite of tools for nuclear systems modeling and simulation that provides comprehensive, verified and validated, user-friendly capabilities for criticality safety, reactor physics, radiation shielding, and sensitivity and uncertainty analysis. Since 1980, regulators, industry, and research institutions around the world have relied on SCALE for nuclear safety analysis and design. SCALE 6.2 provides several new capabilities and significant improvements in many existing features for criticality safety analysis. Enhancements are realized for nuclear data; multigroup resonance self-shielding; continuous-energy Monte Carlo analysis for sensitivity/uncertainty analysis, radiation shielding, and depletion; and graphical user interfaces. An overview of these capabilities is provided in this paper, and additional details are provided in several companion papers.

  5. Post-Fukushima Probabilistic Safety Enhancements of Industry

    Energy Technology Data Exchange (ETDEWEB)

    Na, Janghwan; Jeon, Ho-Jun; Lee, Hyun-Gyo [Korea Hydro and Nuclear Power Co. Ltd. Central Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    Nuclear concerned society as well as regulatory agency of Korea also asked several safety measures be included to the existing safety principles. These measures include the post-Fukushima near action items, several mid-long term obligations for severe accidents and rare external hazards which were disregarded due to unlikely event probabilities. This paper illustrates some activities being done or planned in view of probabilistic assessment boundaries; 1) Items currently performed by industry, 2) Regulatory measures which will impact to the industry activities, 3) Activities planned by mid-long bases. After the Fukushima accident, the significance of severe accidents and PSA came to the public as well as the industry itself. Among fifty safety-related plans, in this paper, we showed the implementation strategies and interim insights from LPSD PSA. The plans or activities now underway are further enhancing the safety for operating by introducing PSR and construction plants by inclusion of PSA insights into SAR. The main focus for safety improvement is targeted by not only the hardware improvement, but also systematic structure and effective operational improvement. The results of LPSD PSA implementation strategy will contribute to conforming of regulatory requirement and legislation of PSA which requests the application of extended scope of analysis, new methodology, PSA quality, living PSA through technically sound and application- specific PSA models.

  6. Post-Fukushima Probabilistic Safety Enhancements of Industry

    International Nuclear Information System (INIS)

    Nuclear concerned society as well as regulatory agency of Korea also asked several safety measures be included to the existing safety principles. These measures include the post-Fukushima near action items, several mid-long term obligations for severe accidents and rare external hazards which were disregarded due to unlikely event probabilities. This paper illustrates some activities being done or planned in view of probabilistic assessment boundaries; 1) Items currently performed by industry, 2) Regulatory measures which will impact to the industry activities, 3) Activities planned by mid-long bases. After the Fukushima accident, the significance of severe accidents and PSA came to the public as well as the industry itself. Among fifty safety-related plans, in this paper, we showed the implementation strategies and interim insights from LPSD PSA. The plans or activities now underway are further enhancing the safety for operating by introducing PSR and construction plants by inclusion of PSA insights into SAR. The main focus for safety improvement is targeted by not only the hardware improvement, but also systematic structure and effective operational improvement. The results of LPSD PSA implementation strategy will contribute to conforming of regulatory requirement and legislation of PSA which requests the application of extended scope of analysis, new methodology, PSA quality, living PSA through technically sound and application- specific PSA models

  7. 78 FR 52899 - Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility...

    Science.gov (United States)

    2013-08-27

    ... Food and Nutrition Service Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility--Listening Sessions AGENCY: Food and Nutrition Service (FNS), USDA. ACTION: Notice. SUMMARY: This... regarding Supplemental Nutrition Assistance Program (SNAP) retailer eligibility requirements (78 FR...

  8. Increased safety and reduction of congestion by using driver assistance technology: dream or reality?

    NARCIS (Netherlands)

    Schijndel-de Nooij, M. van

    2009-01-01

    As accidents with trucks have a large influence on traffic flow, a large pilot on the effect of driver assistance systems was kicked off in July 2008 in the Netherlands. The primary goals of the pilot are to assess the potential for improving safety and maintaining traffic flow. The potential contri

  9. Pacific Northwest Laboratory annual report for 1990 to the Assistant Secretary for Environment, Safety, and Health

    Energy Technology Data Exchange (ETDEWEB)

    Faust, L.G.; Moraski, R.V.; Selby, J.M.

    1991-05-01

    Part 5 of the 1990 Annual Report to the US Department of Energy's Assistant Secretary for Environment, Safety, and Health presents Pacific Northwest Laboratory's progress on work performed for the Office of Environmental Guidance, the Office of Environmental Compliance, the Office of Environmental Audit, the Office of National Environmental Policy Act Project Assistance, the Office of Nuclear Safety, the Office of Safety Compliance, and the Office of Policy and Standards. For each project, as identified by the Field Work Proposal, there is an article describing progress made during fiscal year 1990. Authors of these articles represent a broad spectrum of capabilities derived from five of the seven technical centers of the Laboratory, reflecting the interdisciplinary nature of the work.

  10. Pacific Northwest Laboratory annual report for 1989 to the Assistant Secretary for Environment, Safety, and Health

    International Nuclear Information System (INIS)

    Part 5 of the 1989 Annual Report to the US Department of Energy's Assistant Secretary for Environment, Safety, and Health presents Pacific Northwest Laboratory's progress on work performed for the Office of Environmental Guidance and Compliance, the Office of Environmental Audit, the Office of National Environmental Policy Act Project Assistance, the Office of Nuclear Safety, the Office of Safety Compliance, and the Office of Policy and Standards. For each project, as identified by the Field Work Proposal, there is an article describing progress made during fiscal year 1989. Authors of these articles represent a broad spectrum of capabilities derived from five of the seven technical centers of the Laboratory, reflecting the interdisciplinary nature of the work. 35 refs., 1 fig

  11. Development of safety enhancement technology of containment building

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Rim; Song, Y. C.; Kim, W. B. [Korea Electric Power Research Institute, Taejeon (Korea)

    2002-04-01

    A containment building, which is a final barrier to prevent the release of radioactivity under a postulated severe accident condition, has to be ensured the structural integrity and capacity that are essential elements for safety of the NPP(Nuclear Power Plant) in service. Therefore, even when a disaster such as earthquake occurs its integrity has to be maintained, as well as an appropriate counter-plan for the aging phenomenon of the major structural materials due to increasing of the service time has to be established. To establish the safety and capacity enhancement of containment building, the following 5 research tasks were performed for three years. - Earthquake response measurement and verification of SSI analysis technique - Development of aging database system and aging database construction of containment building. - Development of survey, detection and assessment technology of concrete aging: drawing up of a guide book - Development of survey, detection and assessment technology of Epoxy-liner aging. - Development of nonlinear material models : biaxal strength envelope and uniaxial tension softening model of plain concrete. The research products in this study can be applied to the structural safety enhancement and life extension of NPP and the other electric power structures. 51 refs., 107 figs., 30 tabs. (Author)

  12. Enhancement of safety at nuclear facilities in Pakistan

    International Nuclear Information System (INIS)

    Pakistan is benefiting from nuclear technology mostly in health and energy sectors as well as agriculture and industry and has an impeccable safety record. At the national level uses of nuclear technology started in 1955 resulting in the operation of Karachi Radioisotope Center, Karachi, in December 1960. Pakistan Nuclear Safety Committee (PNSC) was formulated in 1964 with subsequent promulgation of Pakistan Atomic Energy Commission (PAEC) Ordinance in 1965 to cope with the anticipated introduction of a research reactor, namely PARR-I, and a nuclear power plant, namely KANUPP. Since then Pakistan's nuclear program has expanded to include numerous nuclear facilities of varied nature. This program has definite economic and social impacts by producing electricity, treating and diagnosing cancer patients, and introducing better crop varieties. Appropriate radiation protection includes a number of measures including database of sealed radiation sources at PAEC operated nuclear facilities, see Table l, updated during periodic physical verification of these sources, strict adherence to the BSS-115, IAEA recommended enforcement of zoning at research reactors and NPPs, etc. Pakistan is party to several international conventions and treaties, such as Convention of Nuclear Safety and Early Notification, to improve and enhance safety at its nuclear facilities. In addition Pakistan generally and PAEC particularly believes in a blend of prudent regulations and good/best practices. This is described in this paper. (Author)

  13. Handbook of driver assistance systems basic information, components and systems for active safety and comfort

    CERN Document Server

    Hakuli, Stephan; Lotz, Felix; Singer, Christina

    2016-01-01

    This fundamental work explains in detail systems for active safety and driver assistance, considering both their structure and their function. These include the well-known standard systems such as Anti-lock braking system (ABS), Electronic Stability Control (ESC) or Adaptive Cruise Control (ACC). But it includes also new systems for protecting collisions protection, for changing the lane, or for convenient parking. The book aims at giving a complete picture focusing on the entire system. First, it describes the components which are necessary for assistance systems, such as sensors, actuators, mechatronic subsystems, and control elements. Then, it explains key features for the user-friendly design of human-machine interfaces between driver and assistance system. Finally, important characteristic features of driver assistance systems for particular vehicles are presented: Systems for commercial vehicles and motorcycles.

  14. BEST AVAILABLE TECHNIQUES AS ENVIRONMENTAL SAFETY ENHANCEMENT INSTRUMENTS

    Directory of Open Access Journals (Sweden)

    Michael Begak

    2015-09-01

    Full Text Available Environmental safety enhancement is an important objective for any state. It is vital for the Russian Federation, where economic activities resulted in environmental deterioration. Current development has to provide both for the growth of the national economy and for the minimization of negative environmental impacts. These issues could be addressed via development and implementation of the National Environmental Strategies, which have to become a basis for setting national targets and implementing modern instruments of environmental safety. European experience proves that the Best Available Techniques (BAT are considered as instruments applicable to improve environmental performance and resource efficiency for major enterprises. Main components of the national environmental strategy are discussed, and prerequisites for its implementation (such as ratification of Espoo and Aarhus conventions and practical application of BAT principles in environmental regulation are suggested as a result of the analysis of new legislative and managerial approaches emerging in Russia.

  15. Coaxial needle insertion assistant with enhanced force feedback.

    Science.gov (United States)

    De Lorenzo, Danilo; Koseki, Yoshihiko; De Momi, Elena; Chinzei, Kiyoyuki; Okamura, Allison M

    2013-02-01

    Many medical procedures involving needle insertion into soft tissues, such as anesthesia, biopsy, brachytherapy, and placement of electrodes, are performed without image guidance. In such procedures, haptic detection of changing tissue properties at different depths during needle insertion is important for needle localization and detection of subsurface structures. However, changes in tissue mechanical properties deep inside the tissue are difficult for human operators to sense, because the relatively large friction force between the needle shaft and the surrounding tissue masks the smaller tip forces. A novel robotic coaxial needle insertion assistant, which enhances operator force perception, is presented. This one-degree-of-freedom cable-driven robot provides to the operator a scaled version of the force applied by the needle tip to the tissue, using a novel design and sensors that separate the needle tip force from the shaft friction force. The ability of human operators to use the robot to detect membranes embedded in artificial soft tissue was tested under the conditions of 1) tip force and shaft force feedback, and 2) tip force only feedback. The ratio of successful to unsuccessful membrane detections was significantly higher (up to 50%) when only the needle tip force was provided to the user. PMID:23193302

  16. Smart Roadside System for Driver Assistance and Safety Warnings: Framework and Applications

    OpenAIRE

    Han Byeog Cho; Hyun Suk Kim; Jeong Ah Jang

    2011-01-01

    The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs). This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system f...

  17. Engineering and Safety Partnership Enhances Safety of the Space Shuttle Program (SSP)

    Science.gov (United States)

    Duarte, Alberto

    2007-01-01

    difference for the safety of the Space Shuttle Vehicle, its crew, and personnel. Because of the MSERP's valuable contribution to the assessment of safety risk for the SSP, this paper also proposes an enhanced Panel concept that takes this successful partnership concept to a higher level of 'true partnership'. The proposed panel is aimed to be responsible for the review and assessment of all risk relative to Safety for new and future aerospace and related programs.

  18. Use of DRACS to Enhance HTGRs Passive Safety and Economy

    International Nuclear Information System (INIS)

    This paper discusses the use of DRACS to Enhance HTGRs Passive Safety and Economy. One of the important requirements for Gen. IV High Temperature Gas Cooled Reactors (HTGR) is passive safety. Currently all the HTGR designs use Reactor Vessel Auxiliary Cooling System (RVACS) for passive decay heat removal. (1) The decay heat first is transferred to core barrel by conduction and radiation, and then to reactor vessel by thermal radiation and convection; finally the decay heat is transferred to natural circulated air or water systems. RVACS can be characterized as a surface based decay heat removal system. Similar concepts have been widely used in sodium cooled fast reactor (SFR) designs, advanced light water reactors like AP1000. The RVACS is especially suitable for smaller power reactors since small systems have relatively larger surface area. RVACS tends to be less expensive. However, it limits the largest achievable power level for modular HTGRs due to the mismatch between the reactor power (proportional to volume) and decay heat removal capability (proportional to surface). When the relative decay heat removal capability is reduced, the peak fuel temperature increases, even close to the design limit. Annual designs with internal reflector can mitigate this effect therefore further increase the power. Another way to increase power is to increase power density. However, it is also limited by the decay heat removal capability. Besides safety, HTGRs also need to be economical in order to compete with other reactor designs. The limit of decay heat removal capability set by using RVACS has affected the economy of HTGRs. Forsberg (2) pointed out other disadvantages of using RVACS such as conflicting functional requirements for the reactor vessel and scaling distortion for integral effect test of the system performance. A potential alternative solution is to use a volume based passive decay removal system, call Direct Reactor Auxiliary Cooling Systems (DRACS), to remove

  19. Use of DRACS to Enhance HTGRs Passive Safety and Economy

    Energy Technology Data Exchange (ETDEWEB)

    Haihua Zhao; Hongbin Zhang; Ling Zou

    2011-06-01

    This paper discusses the use of DRACS to Enhance HTGRs Passive Safety and Economy. One of the important requirements for Gen. IV High Temperature Gas Cooled Reactors (HTGR) is passive safety. Currently all the HTGR designs use Reactor Vessel Auxiliary Cooling System (RVACS) for passive decay heat removal. [1] The decay heat first is transferred to core barrel by conduction and radiation, and then to reactor vessel by thermal radiation and convection; finally the decay heat is transferred to natural circulated air or water systems. RVACS can be characterized as a surface based decay heat removal system. Similar concepts have been widely used in sodium cooled fast reactor (SFR) designs, advanced light water reactors like AP1000. The RVACS is especially suitable for smaller power reactors since small systems have relatively larger surface area. RVACS tends to be less expensive. However, it limits the largest achievable power level for modular HTGRs due to the mismatch between the reactor power (proportional to volume) and decay heat removal capability (proportional to surface). When the relative decay heat removal capability is reduced, the peak fuel temperature increases, even close to the design limit. Annual designs with internal reflector can mitigate this effect therefore further increase the power. Another way to increase power is to increase power density. However, it is also limited by the decay heat removal capability. Besides safety, HTGRs also need to be economical in order to compete with other reactor designs. The limit of decay heat removal capability set by using RVACS has affected the economy of HTGRs. Forsberg [2] pointed out other disadvantages of using RVACS such as conflicting functional requirements for the reactor vessel and scaling distortion for integral effect test of the system performance. A potential alternative solution is to use a volume based passive decay removal system, call Direct Reactor Auxiliary Cooling Systems (DRACS), to remove

  20. Pacific Northwest Laboratory annual report for 1980 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health and safety

    International Nuclear Information System (INIS)

    Pacific Northwest Laboratory's (PNL) 1980 annual report to the DOE Assistant Secretary for Environment describes research in environment, health, and safety conducted during fiscal year 1980. Part 5 includes technology assessments for natural gas, enhanced oil recovery, oil shale, uranium mining, magnetic fusion energy, solar energy, uranium enrichment and industrial energy utilization; regional analysis studies of environmental transport and community impacts; environmental and safety engineering for LNG, oil spills, LPG, shale oil waste waters, geothermal liquid waste disposal, compressed air energy storage, and nuclear/fusion fuel cycles; operational and environmental safety studies of decommissioning, environmental monitoring, personnel dosimetry, and analysis of criticality safety; health physics studies; and epidemiological studies. Also included are an author index, organization of PNL charts and distribution lists of the annual report, along with lists of presentations and publications

  1. Enhancing Patient Safety Using Clinical Nursing Data: A Pilot Study.

    Science.gov (United States)

    Choi, Jeeyae; Choi, Jeungok E

    2016-01-01

    To enhance patient safety from falls, many hospital information systems have been implemented to collect clinical data from the bedside and have used the information to improve fall prevention care. However, most of them use administrative data not clinical nursing data. This necessitated the development of a web-based Nursing Practice and Research Information Management System (NPRIMS) that processes clinical nursing data to measure nurses' delivery of fall prevention care and its impact on patient outcomes. This pilot study developed computer algorithms based on a falls prevention protocol and programmed the prototype NPRIMS. It successfully measured the performance of nursing care delivered and its impact on patient outcomes using clinical nursing data from the study site. Results of the study revealed that NPRIMS has the potential to pinpoint components of nursing processes that are in need of improvement for preventing patient from falls. PMID:27332171

  2. Enhanced safety in the storage of fissile materials

    International Nuclear Information System (INIS)

    An inexpensive boron-loaded liner of epoxy resin for fissile-material storage containers was developed that can be easily fabricated of readily available, low-cost materials. Computer calculations indicate reactivity will be reduced substantially if this neutron-absorbing liner is added to containers in a typical storage array. These calculations compare favorably with neutron-attenuation experiments with thermal and fission neutron spectra, and tests at the Fire Test Facility indicate the epoxy resin will survive extreme environmental and accident conditions. The fire-resistant and insulating properties of the epoxy-resin liner further augment its ability to protect fissile materials. Boron-loaded epoxy resin is adaptable to many tasks but is particularly useful for providing enhanced criticality safety in the packaging and storage of fissile materials

  3. Contractors’ Attitude towards Enhancing Safety Performance: Case Study on Construction Firms in Penang

    OpenAIRE

    Ulang N. Md.; Ming Sing S.; Baharum F.; Agus Salim N.A.

    2014-01-01

    A qualitative study was conducted to investigate the contractors’ attitude towards enhancing the safety performance in construction site. Despite the fact that there are many safety initiatives established by the government, the rates of accidents are still in a critically high condition. Thus the purpose of this research is to study the contractors’ attitude towards enhancing the implementation of safety management system in construction site in order to increase the safety awareness of cons...

  4. Antenna-assisted enhanced transmission through subwavelength nanoholes

    DEFF Research Database (Denmark)

    Xiao, Sanshui; Peng, Liang; Mortensen, Asger

    2010-01-01

    By structural engineering of sub-wavelength apertures, we numerically demonstrate that transmission through apertures can be significantly enhanced. Based on equivalent circuit theory analysis, structured apertures are obtained with a 1900-fold transmission enhancement factor. We show that the...

  5. Using Total Lightning Observations to Enhance Lightning Safety

    Science.gov (United States)

    Stano, Geoffrey T.

    2012-01-01

    Lightning is often the underrated threat faced by the public when it comes to dangerous weather phenomena. Typically, larger scale events such as floods, hurricanes, and tornadoes receive the vast majority of attention by both the general population and the media. This comes from the fact that these phenomena are large, longer lasting, can impact a large swath of society at one time, and are dangerous events. The threat of lightning is far more isolated on a case by case basis, although millions of cloud-to-ground lightning strikes hit this United States each year. While attention is given to larger meteorological events, lightning is the second leading cause of weather related deaths in the United States. This information raises the question of what steps can be taken to improve lightning safety. Already, the meteorological community s understanding of lightning has increased over the last 20 years. Lightning safety is now better addressed with the National Weather Service s access to the National Lightning Detection Network data and enhanced wording in their severe weather warnings. Also, local groups and organizations are working to improve public awareness of lightning safety with easy phrases to remember, such as "When Thunder Roars, Go Indoors." The impacts can be seen in the greater array of contingency plans, from airports to sports stadiums, addressing the threat of lightning. Improvements can still be made and newer technologies may offer new tools as we look towards the future. One of these tools is a network of sensors called a lightning mapping array (LMA). Several of these networks exist across the United States. NASA s Short-term Prediction Research and Transition Center (SPoRT), part of the Marshall Spaceflight Center, has access to three of these networks from Huntsville, Alabama, the Kennedy Space Center, and Washington D.C. The SPoRT program s mission is to help transition unique products and observations into the operational forecast environment

  6. Public safety investigations-A new evolutionary step in safety enhancement?

    International Nuclear Information System (INIS)

    A historical overview highlights the evolutionary nature of developments in accident investigations in the transport industry. Based on a series of major events outside transportation, the concept of accident investigations has broadened to other domains and to a widening of the scope of the investigation. Consequently, existing investigation boards are forced to adapt their mandates, missions and methods. With the introduction of social risk perception and application of the concept of safety investigation in the public sector, a change of focus towards the aftermath and non-technical issues of a more generic nature emerges. This expansion has also gained the interest of social sciences and public governance, generating new underlying models and theories on risk and responsibility. The evolutionary development of safety investigations is demonstrated by the various organisational forms which shaped accident investigations in different countries. Underneath these organisational differences, a need for a common methodology and a reflection on fundamental notions is discussed. In particular differences among human operator models, the allocation of responsibilities in design concepts and methodological issue are elaborated. The needs and opportunities for a transition from accident prevention towards systems change are indicated. At present, the situation is ambiguous. An encompassing inventory can only provide a general oversight over emerging trends and lacks analytic rigor on specific topics. The societal dimensions, institutional changes at the level of governance and control and the powers that advocate or challenge investigations are not yet fully described. Therefore, in the conclusions a small number of critical challenges and threats are identified that should be open to scrutiny in order to facilitate a new, evolutionary step in safety enhancement.

  7. Safety and Response-Time Analysis of an Automotive Accident Assistance Service

    Science.gov (United States)

    Argent-Katwala, Ashok; Clark, Allan; Foster, Howard; Gilmore, Stephen; Mayer, Philip; Tribastone, Mirco

    In the present paper we assess both the safety properties and the response-time profile of a subscription service which provides medical assistance to drivers who are injured in vehicular collisions. We use both timed and untimed process calculi cooperatively to perform the required analysis. The formal analysis tools used are hosted on a high-level modelling platform with support for scripting and orchestration which enables users to build custom analysis processes from the general-purpose analysers which are hosted as services on the platform.

  8. Pacific Northwest Laboratory annual report for 1987 to the Assistant Secretary for Environment, Safety, and Health: Part 5: Environment, safety, health, and quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    Faust, L.G.; Steelman, B.L.; Selby, J.M.

    1988-02-01

    Part 5 of the 1987 Annual Report to the US Department of Energy's Assistant Secretary for Environment, Safety, and Health presents Pacific Northwest Laboratory's progress on work performed for the Office of Nuclear Safety, the Office of Environmental Guidance and Compliance, the Office of Environmental Audit, and the Office of National Environmental Policy Act Project Assistance. For each project, as identified by the Field Work Proposal, articles describe progress made during fiscal year 1987. Authors of these articles represent a broad spectrum of capabilities derived from five of the seven technical centers of the Laboratory, reflecting the interdisciplinary nature of the work.

  9. Pacific Northwest Laboratory annual report for 1987 to the Assistant Secretary for Environment, Safety, and Health: Part 5: Environment, safety, health, and quality assurance

    International Nuclear Information System (INIS)

    Part 5 of the 1987 Annual Report to the US Department of Energy's Assistant Secretary for Environment, Safety, and Health presents Pacific Northwest Laboratory's progress on work performed for the Office of Nuclear Safety, the Office of Environmental Guidance and Compliance, the Office of Environmental Audit, and the Office of National Environmental Policy Act Project Assistance. For each project, as identified by the Field Work Proposal, articles describe progress made during fiscal year 1987. Authors of these articles represent a broad spectrum of capabilities derived from five of the seven technical centers of the Laboratory, reflecting the interdisciplinary nature of the work

  10. Enhanced neurorehabilitation techniques in the DVBIC Assisted Living Pilot Project.

    Science.gov (United States)

    Hoffman, Stuart W; Shesko, Kristina; Harrison, Catherine R

    2010-01-01

    Traumatic Brain Injury has been labeled the "silent epidemic" in our current wars. Both CBO and the RAND reports predict that the costs of these injuries will be both extensive and enduring. The projected costs are based not only upon the loss contribution of these warriors to our economy, but also the long-term medical and assistive care that will be needed to support these veterans for decades to come. Thus, the primary goal of the Assisted Living Pilot Project (ALPP) at the Defense and Veterans Brain Injury Center - Johnstown (DVBIC-J) is to promote the ability of the injured warrior to move from assisted living to living independently and to be self-supporting by providing a continuum of care. To accomplish this goal the DVBIC-J ALPP is providing full set of traditional services (physical, occupational, speech, psychological/cognitive, social/familial, vocational, and spiritual), along with "cutting-edge" rehabilitative treatment technologies. These cutting-edge therapies include transdisciplinary clinical consultations, interactive patient and family counseling, and telemedicine-teleconferencing for clinical evaluations and family/significant other care participation. These services will be available to those who require assisted living through their progression to community re-entry. The ALPP also serves as a vehicle for clinical trials to investigate the effects of an enriched environment (e.g., recreational therapies, massage, multisensory stimulation, etc.) on neurorehabilitation therapy, rural telemedicine for servicemembers with traumatic brain injury, and long-term outcome measures of those who have received neurorehabilitation services at the DVBIC-J site. DVBIC-J is also developing collaborative projects with universities and private industry to create an incubator for new rehabilitation technologies. The technologies that DVBIC-J will be focusing on will include assistive technologies (to assist cognitive, physical, and communicative impairments

  11. Collaborative Assistive Robot for Mobility Enhancement (CARMEN) The bare necessities assisted wheelchair navigation and beyond

    CERN Document Server

    Urdiales, Cristina

    2012-01-01

    In nowadays aging society, many people require mobility assistance. Sometimes, assistive devices need a certain degree of autonomy when users' disabilities difficult manual control. However, clinicians report that excessive assistance may lead to loss of residual skills and frustration. Shared control focuses on deciding when users need help and providing it. Collaborative control aims at giving just the right amount of help in a transparent, seamless way. This book presents the collaborative control paradigm. User performance may be indicative of physical/cognitive condition, so it is used to decide how much help is needed. Besides, collaborative control integrates machine and user commands so that people contribute to self-motion at all times. Collaborative control was extensively tested for 3 years using a robotized wheelchair at a rehabilitation hospital in Rome with volunteer inpatients presenting different disabilities, ranging from mild to severe. We also present a taxonomy of common metrics for wheelc...

  12. Understanding safety in healthcare: the system evolution, erosion and enhancement model

    Directory of Open Access Journals (Sweden)

    Jane Carthey

    2013-12-01

    Full Text Available The paper summarises previous theories of accident causation, human error, foresight, resilience and system migration. Five lessons from these theories are used as the foundation for a new model which describes how patient safety emerges in complex systems like healthcare: the System Evolution Erosion and Enhancement model. It is concluded that to improve patient safety, healthcare organisations need to understand how system evolution both enhances and erodes patient safety.

  13. Surveying Wearable Human Assistive Technology for Life and Safety Critical Applications: Standards, Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Muhammad Mahtab Alam

    2014-05-01

    Full Text Available In this survey a new application paradigm life and safety for critical operations and missions using wearable Wireless Body Area Networks (WBANs technology is introduced. This paradigm has a vast scope of applications, including disaster management, worker safety in harsh environments such as roadside and building workers, mobile health monitoring, ambient assisted living and many more. It is often the case that during the critical operations and the target conditions, the existing infrastructure is either absent, damaged or overcrowded. In this context, it is envisioned that WBANs will enable the quick deployment of ad-hoc/on-the-fly communication networks to help save many lives and ensuring people’s safety. However, to understand the applications more deeply and their specific characteristics and requirements, this survey presents a comprehensive study on the applications scenarios, their context and specific requirements. It explores details of the key enabling standards, existing state-of-the-art research studies, and projects to understand their limitations before realizing aforementioned applications. Application-specific challenges and issues are discussed comprehensively from various perspectives and future research and development directions are highlighted as an inspiration for new innovative solutions. To conclude, this survey opens up a good opportunity for companies and research centers to investigate old but still new problems, in the realm of wearable technologies, which are increasingly evolving and getting more and more attention recently.

  14. Surveying wearable human assistive technology for life and safety critical applications: standards, challenges and opportunities.

    Science.gov (United States)

    Alam, Muhammad Mahtab; Ben Hamida, Elyes

    2014-05-23

    In this survey a new application paradigm life and safety for critical operations and missions using wearable Wireless Body Area Networks (WBANs) technology is introduced. This paradigm has a vast scope of applications, including disaster management, worker safety in harsh environments such as roadside and building workers, mobile health monitoring, ambient assisted living and many more. It is often the case that during the critical operations and the target conditions, the existing infrastructure is either absent, damaged or overcrowded. In this context, it is envisioned that WBANs will enable the quick deployment of ad-hoc/on-the-fly communication networks to help save many lives and ensuring people's safety. However, to understand the applications more deeply and their specific characteristics and requirements, this survey presents a comprehensive study on the applications scenarios, their context and specific requirements. It explores details of the key enabling standards, existing state-of-the-art research studies, and projects to understand their limitations before realizing aforementioned applications. Application-specific challenges and issues are discussed comprehensively from various perspectives and future research and development directions are highlighted as an inspiration for new innovative solutions. To conclude, this survey opens up a good opportunity for companies and research centers to investigate old but still new problems, in the realm of wearable technologies, which are increasingly evolving and getting more and more attention recently.

  15. Strengthening leadership as a catalyst for enhanced patient safety culture

    DEFF Research Database (Denmark)

    Kristensen, Solvejg; Christensen, Karl Bang; Jaquet, Annette;

    2016-01-01

    in the Safety Attitudes Questionnaire. To broaden knowledge and strengthen leadership skills, a multicomponent programme consisting of academic input, exercises, reflections and discussions, networking, and action learning was implemented among the clinical area level leaders. RESULTS: In total, 358 and 325...... over time. 6 patient safety culture dimensions became more positive (increase in mean) (pstress recognition (p

  16. Contractors’ Attitude towards Enhancing Safety Performance: Case Study on Construction Firms in Penang

    Directory of Open Access Journals (Sweden)

    Ulang N. Md

    2014-01-01

    Full Text Available A qualitative study was conducted to investigate the contractors’ attitude towards enhancing the safety performance in construction site. Despite the fact that there are many safety initiatives established by the government, the rates of accidents are still in a critically high condition. Thus the purpose of this research is to study the contractors’ attitude towards enhancing the implementation of safety management system in construction site in order to increase the safety awareness of construction practitioners in construction site and improve the safety condition of construction sites. This study is conducted through oral interviews with the construction practitioners, and visual inspection of construction sites. The attitudes of contractors are evaluated from 3 aspects: Contractors’ efforts in implement and enforce the safety rules, Contractors efforts in overcoming the rate of accidents, and Reasons given by the contractors for not implement safety law.

  17. Overview of PHARE projects implemented in Romania between 1997 and 2008 for enhancing the nuclear safety level

    International Nuclear Information System (INIS)

    Through the Poland Hungary Aid for Reconstruction of the Economy (PHARE) programme, the European Commission (EC) supported the transition of the Eastern European states to the European market economy. PHARE was a pre-accession financial assistance programme which involved countries from Central and Eastern Europe that applied to become members of the European Union. The paper presents a synthesis of the projects carried out in Romania for enhancing nuclear safety by consolidating key areas such as Regulatory Activities, Radioactive Waste Management and On-Site assistance, in order to fulfil the requirements for accession to the European Union. Statistical considerations on the impact of the projects are also proposed and an analysis of the methodology of intervention is made.

  18. The enhancement of nuclear safety: Basic principles and approaches to ensure the operation safety of NPP's in Korea

    International Nuclear Information System (INIS)

    Nuclear safety of NPPs should receive the highest priority concerns in any mode of operation because various operational transients can develop into an accident of serious consequence. In most nuclear countries, two-tier approach is commonly adopted to assure the operational safety; (1) various operational and maintenance activities by the utility which has the primary responsibility for the safety of the facility, (2) surveillance and inspection by the government authority which officially confirms the nuclear safety to protect the public from the radiation hazards. The utility has to improve the economy of the plant operation and at the same time has to enhance the safety through the achievement of high quality and reliability in operation and maintenance. The regulatory body, in the meantime, confirms the operational safety through the safety review and inspection activities in the form of preoperational inspection, periodical inspection, daily inspection, special inspection, etc. This paper reviews the basic principles for operation and maintenance of NPP, and the fundamental framework of the roles and responsibilities of the utility and the regulatory body with a view to achieving the operational safety. Also discussed is the regulatory effort in Korea to verify the adequacy of the plant management

  19. [Electrically assisted bicycles: health enhancement or "green" gadget?].

    Science.gov (United States)

    Welker, J; Cornuz, J; Gojanovic, B

    2012-07-25

    Electrically assisted bicycles (EAB) are flourishing in cities throughout the world and capitalize on ecological and practical advantages, helping in the fight against pollution, CO2 emissions and traffic jam. Human power is necessary to activate the electrical support, so that it equals to a moderate intensity physical activity (> 3 MET), or a vigorous one on hilly courses (>6 MET). The ecological benefits are obvious and transportation departments tend to support citizens who purchase one. EAB offer increased mobility at speeds of 15 to 25 km/h depending on hills and fitness of the rider, but could cause more accidents. EAB is linked to a real physical activity beneficial for health, but potentially more dangerous than a traditional bicycle. PMID:22913003

  20. Enhancing the safety culture in nuclear installations through efficient regulation

    International Nuclear Information System (INIS)

    The safety culture of a nuclear installation is greatly influenced by the external regulatory agencies with which it relates or interacts. These external regulatory agencies create demands for compliance with national industry or governmental regulatory standards and requirements imposed to provide for the public health and safety. While these national regulations can influence nuclear safety, no amount of regulation can ensure safety if those who operate the nuclear installations do not or cannot take it upon themselves to operate as safely as possible. It is not possible, nor is it desirable, for a regulatory agency to have the ultimate responsibility for the safety of nuclear installations. Good judgement and safe operating philosophy cannot be legislated. There must exist a safety culture in nuclear installations which recognizes the primary and ultimate responsibility for nuclear safety lies with those who manage and operate the installation. Thus, effective regulation must exist which promotes an environment that provides the nuclear installation the latitude it needs to apply innovative solutions to improve maintenance, operations, and training, and fosters a quest for excellence. (author)

  1. Enhancing NPP Safety Through an Effective Dependability Management

    International Nuclear Information System (INIS)

    Taking into account the importance of the continuous improvement of the performance and reliability of a NPP and practical measures to strengthen nuclear safety and security, it is to be noted that a good management for a nuclear power reactor involves a ''good dependability management'' of the activities, such as: Reliability, Availability, Maintainability (RAM) and maintenance support. In order to evaluate certain safety assessment criteria intended to be applied at the level of the nuclear reactor unit management, equipment dependability indicators and their impact over the availability and reactor safety have to be evaluated. Reactor equipment dependability indicators provide a quantitative indication of equipment RAM performances (Reliability, Availability and Maintenance). One of the important benefits of maintenance and failure data gathering is that it can be used as a support of probabilistic safety assessment (PSA). Also, a good dependability management implementation may be used to complement reactor level unit performance indicators in the field of safe operation, maintenance and improving operating parameters, as well as for Strengthening Safety and Improving Reliability of a NPP. This paper underlines the importance of nuclear safety and security as prerequisites for nuclear power. In addition, it demonstrates how different technical aspects, through implementation of a good dependability management, contribute to a strengthened safety and an improvement of availability of the NPP through dependability indicators determination and evaluation. (author)

  2. IRSN - Annual Report 2013. Financial Report 2013. Enhancing nuclear safety

    International Nuclear Information System (INIS)

    IRSN, a public entity with industrial and commercial activities, is placed under the joint authority of the Ministries of Defense, Environment, Industry, Research, and Health. It is the nation's public service expert in nuclear and radiation risks, and its activities cover all the related scientific and technical issues. Its areas of specialization include the environment and radiological emergency response, human radiation protection in both a medical and professional capacity, and in both normal and post-accident situations, the prevention of major accidents, nuclear reactor safety, as well as safety in nuclear plants and laboratories, transport and waste treatment, and nuclear defense and security expertise. IRSN interacts with all parties concerned by these risks (public authorities, in particular nuclear safety and security authorities, local authorities, companies, research organizations, stakeholders' associations, etc.) to contribute to public policy issues relating to nuclear safety, human and environmental protection against ionizing radiation, and the protection of nuclear materials, facilities, and transport against the risk of malicious acts. This document is the 2013 issue of IRSN's activity report. Content: 1 - Organization, key figures; 2 - Strategy: Progress and main activities in 2013, Transparency and communications policy, Promoting a safety and radiation protection culture; 3 - Activities: Safety (Safety of existing facilities, Studies and researches, About defense, Conducting assessments of future facilities); Nuclear security and non-proliferation (Nuclear security activities, International non-proliferation controls); Radiation protection - environment and human health (Environmental and population exposure, Radiation protection in the workplace, Effects of chronic exposure, Protection in health care); Emergency and post-accident situations efficiency; 4 - Efficiency: Health, safety, environmental, protection and quality, Human resources

  3. Smart roadside system for driver assistance and safety warnings: framework and applications.

    Science.gov (United States)

    Jang, Jeong Ah; Kim, Hyun Suk; Cho, Han Byeog

    2011-01-01

    The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs). This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system for highways. Evaluation results for the two services are then shown using a micro-simulation method. In the given real-time applications for drivers, the framework and certain algorithms produce a very efficient solution with respect to the roadway type features and sensor type use. PMID:22164025

  4. Smart roadside system for driver assistance and safety warnings: framework and applications.

    Science.gov (United States)

    Jang, Jeong Ah; Kim, Hyun Suk; Cho, Han Byeog

    2011-01-01

    The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs). This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system for highways. Evaluation results for the two services are then shown using a micro-simulation method. In the given real-time applications for drivers, the framework and certain algorithms produce a very efficient solution with respect to the roadway type features and sensor type use.

  5. Smart Roadside System for Driver Assistance and Safety Warnings: Framework and Applications

    Directory of Open Access Journals (Sweden)

    Han Byeog Cho

    2011-07-01

    Full Text Available The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs. This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system for highways. Evaluation results for the two services are then shown using a micro-simulation method. In the given real-time applications for drivers, the framework and certain algorithms produce a very efficient solution with respect to the roadway type features and sensor type use.

  6. Ensuring Food Security Through Enhancing Microbiological Food Safety

    Science.gov (United States)

    Mikš-Krajnik, Marta; Yuk, Hyun-Gyun; Kumar, Amit; Yang, Yishan; Zheng, Qianwang; Kim, Min-Jeong; Ghate, Vinayak; Yuan, Wenqian; Pang, Xinyi

    2015-10-01

    Food safety and food security are interrelated concepts with a profound impact on the quality of human life. Food security describes the overall availability of food at different levels from global to individual household. While, food safety focuses on handling, preparation and storage of foods in order to prevent foodborne illnesses. This review focuses on innovative thermal and non-thermal technologies in the area of food processing as the means to ensure food security through improving food safety with emphasis on the reduction and control of microbiological risks. The antimicrobial efficiency and mechanism of new technologies to extend the shelf life of food product were also discussed.

  7. Resistance transition assisted geometry enhanced magnetoresistance in semiconductors

    International Nuclear Information System (INIS)

    Magnetoresistance (MR) reported in some non-magnetic semiconductors (particularly silicon) has triggered considerable interest owing to the large magnitude of the effect. Here, we showed that MR in lightly doped n-Si can be significantly enhanced by introducing two diodes and proper design of the carrier path [Wan, Nature 477, 304 (2011)]. We designed a geometrical enhanced magnetoresistance (GEMR) device whose room-temperature MR ratio reaching 30% at 0.065 T and 20 000% at 1.2 T, respectively, approaching the performance of commercial MR devices. The mechanism of this GEMR is: the diodes help to define a high resistive state (HRS) and a low resistive state (LRS) in device by their openness and closeness, respectively. The ratio of apparent resistance between HRS and LRS is determined by geometry of silicon wafer and electrodes. Magnetic field could induce a transition from LRS to HRS by reshaping potential and current distribution among silicon wafer, resulting in a giant enhancement of intrinsic MR. We expect that this GEMR could be also realized in other semiconductors. The combination of high sensitivity to low magnetic fields and large high-field response should make this device concept attractive to the magnetic field sensing industry. Moreover, because this MR device is based on a conventional silicon/semiconductor platform, it should be possible to integrate this MR device with existing silicon/semiconductor devices and so aid the development of silicon/semiconductor-based magnetoelectronics. Also combining MR devices and semiconducting devices in a single Si/semiconductor chip may lead to some novel devices with hybrid function, such as electric-magnetic-photonic properties. Our work demonstrates that the charge property of semiconductor can be used in the magnetic sensing industry, where the spin properties of magnetic materials play a role traditionally

  8. Hardware Assisted Fast Volume Rendering with Boundary Enhancement

    Institute of Scientific and Technical Information of China (English)

    童欣; 唐泽圣

    1998-01-01

    In this paper,a new volume rendering method with boundary enhancement is presented.The boundary is extracted and represented by surfaces explicitly,Then,using 3D texture mapping and graphics acceleation hardware,the volume data can be rendered with controllable boundary shading effect almost in real time.Test shows that this method is 4-5 times faster than the previous methods.Moreover,it can also be extended to render the surfaces and the volumetric data together interactively.

  9. Exposing police to pepper spray in training: Inciting injury or enhancing officer safety?

    OpenAIRE

    McLaughlin, Shane

    2007-01-01

    Occupational health and safety regulations in British Columbia prohibit the practice of exposing police to pepper spray in training. Previous research indicates that pepper spray exposure does not cause serious health problems; that traditional training methods are inadequate; and that exposing police to pepper spray in training enhances officer safety in the field. This study explored how exposure to pepper spray in training affects officer safety. To accomplish this, patrol and traffic pers...

  10. The Ex Hoc Infrastructure - Enhancing Traffic Safety through LIfe WArning Systems

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Kristensen, Lars Michael; Eskildsen, Toke;

    2004-01-01

    New pervasive computing technologies for sensing and communication open up novel possibilities for enhancing traffic safety. We are currently designing and implementing the Ex Hoc infrastructure framework for communication among mobile and stationary units including vehicles. The infrastructure...

  11. ENHANCING FOOD SAFETY AND STABILITY THROUGH IRRADIATION: A REVIEW

    Directory of Open Access Journals (Sweden)

    Manzoor Ahmad Shah

    2014-04-01

    Full Text Available Food irradiation is one of the non thermal food processing methods. It is the process of exposing food materials to the controlled amounts of ionizing radiations such as gamma rays, X-rays and accelerated electrons, to improve microbiological safety and stability. Irradiation disrupts the biological processes that lead to decay of food quality. It is an effective tool to reduce food-borne pathogens, spoilage microorganisms and parasites; to extend shelf-life and for insect disinfection. The safety and consumption of irradiated foods have been extensively studied at national levels and in international cooperations and have concluded that foods irradiated under appropriate technologies are both safe and nutritionally adequate. Specific applications of food irradiation have been approved by national legislations of more than 55 countries worldwide. This review aims to discuss the applications of irradiation in food processing with the emphasis on food safety and stability.

  12. Polymer-assisted nanoparticulate contrast-enhancing materials

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The application of nanotechnology in medicine research has significant potential in modern biomedical research,disease diagnosis and therapy.Organic fluorophore-based detection techniques have been widely used as imaging and signal transduction tools for the detection of trace levels of analytes.The photosensitivity of the fluorophores,however,limits their application in such complex environments as living bio-systems where degradation or photobleaching occurs.Inorganic nanoparticles have unique and stable optical,electrical,magnetic and catalytic properties because of their various shapes,sizes and compositions.The potential of the nanoparticles as novel imaging agents has been studied as a possible solution to this problem.Surface modification of inorganic nanoparticles could enhance their biostability in physiological conditions and ability of targeting bioactive molecules.

  13. Challenges and Enhancements to the Safety Culture of the Regulatory Body

    International Nuclear Information System (INIS)

    The workshop opened with presentations by both the NEA Director-General and the chair of the three committees directly involved with the safety culture of the regulatory body (SCRB). The opening session set the scene and gave an overview of the SCRB together with presentations and discussions on priorities and challenges. The main session focused on the principles of the SCRB, its implementation and the challenges and enhancements that are being raised and considered. The workshop concluded with a session that looked at findings and conclusions, the way forward and an agreed position on the SCRB. This document brings together the available presentations (slides) given at the workshop: 1 - Introduction: Challenges and Enhancements to the Safety Culture of the Regulatory Body (J-C. Niel); 2 - Thoughts on Safety Culture from a CSNI Perspective (B. Sheron); 3 - Radiological Protection Culture: CRPPH Work (M. Boyd); 4 - Challenges and Enhancements to Safety Culture of the Regulatory Body (L. Carlsson); 5 - Principles for the safety culture of the regulatory body (P. Tiippana); 6 - NRC's Internal Safety Culture: Successes, Challenges, and the Path Forward (S.G. Burns); 7 - Insights on the Canadian Nuclear Safety Commission's Safety Culture Journey (T. Jamieson); 8 - Lessons Learned from the Fukushima Dai-ichi Accident regarding Safety Culture of Regulatory Body (T. Fuketa); 9 - Challenges to Regulatory Bodies' safety culture (P-F. Chevet); 10 - Regulatory Safety Culture: International Perspective (G. Rzentkowski); 11 - Integration of Safety Research into Safety Culture Concepts (F-P. Weiss); 12 - Radiation Protection and Emergency Management Aspects: Culture drawn up by RP professionals (B. Le Guen); 13 - Closing session panel (L. Carlsson)

  14. The giant enhancement of Fano-type resonance in a gain-assisted silicon slab array

    Institute of Scientific and Technical Information of China (English)

    Dong Zheng-Gao; Li Jia-Qi; Shao Jian; Yu Xiao-Qiang; Wang Yu-Kun; Zhai Ya

    2013-01-01

    Giant resonance enhancement is demonstrated to be due to the Fano interference in a grating waveguide composed of gain-assisted silicon slabs.The Fano mode is characterized by its ultra-narrow asymmetric spectrum,different from that of a pure electric or magnetic dipole.The simulation indicates that a sharp Fano-interfered lineshape is responsible for the giant resonance enhancement featuring the small-gain requirements.

  15. The giant enhancement of Fano-type resonance in a gain-assisted silicon slab array

    International Nuclear Information System (INIS)

    Giant resonance enhancement is demonstrated to be due to the Fano interference in a grating waveguide composed of gain-assisted silicon slabs. The Fano mode is characterized by its ultra-narrow asymmetric spectrum, different from that of a pure electric or magnetic dipole. The simulation indicates that a sharp Fano-interfered lineshape is responsible for the giant resonance enhancement featuring the small-gain requirements. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  16. Safety enhancement of oil trunk pipeline crossing active faults on Sakhalin Island

    Science.gov (United States)

    Tishkina, E.; Antropova, N.; Korotchenko, T.

    2015-11-01

    The article explores the issues concerning safety enhancement of pipeline active fault crossing on Sakhalin Island. Based on the complexity and analysis results, all the faults crossed by pipeline system are classified into five categories - from very simple faults to extremely complex ones. The pipeline fault crossing design is developed in accordance with the fault category. To enhance pipeline safety at fault crossing, a set of methods should be applied: use of pipes of different safety classes and special trench design in accordance with soil permeability characteristics.

  17. Using Computer-Assisted Instruction to Enhance Achievement of English Language Learners

    Science.gov (United States)

    Keengwe, Jared; Hussein, Farhan

    2014-01-01

    Computer-assisted instruction (CAI) in English-Language environments offer practice time, motivates students, enhance student learning, increase authentic materials that students can study, and has the potential to encourage teamwork between students. The findings from this particular study suggested that students who used computer assisted…

  18. 78 FR 51136 - Request for Information: Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food...

    Science.gov (United States)

    2013-08-20

    ... Food and Nutrition Service Request for Information: Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility AGENCY: Food and Nutrition Service, USDA. ACTION: Notice. SUMMARY: Sections 3(k), (p) and (r), Section 7, and Section 9 of the Food and Nutrition Act of 2008 (``the...

  19. ENHANCING FOOD SAFETY AND STABILITY THROUGH IRRADIATION: A REVIEW

    OpenAIRE

    Manzoor Ahmad Shah; Shabir Ahmad Mir; Showket Ahmad Pala

    2014-01-01

    Food irradiation is one of the non thermal food processing methods. It is the process of exposing food materials to the controlled amounts of ionizing radiations such as gamma rays, X-rays and accelerated electrons, to improve microbiological safety and stability. Irradiation disrupts the biological processes that lead to decay of food quality. It is an effective tool to reduce food-borne pathogens, spoilage microorganisms and parasites; to extend shelf-life and for insect disinfection. The s...

  20. Effectiveness evaluation methodology for safety processes to enhance organisational culture in hazardous installations.

    Science.gov (United States)

    Mengolini, A; Debarberis, L

    2008-06-30

    Safety performance indicators are widely collected and used in hazardous installations. The IAEA, OECD and other international organisations have developed approaches that strongly promote deployment of safety performance indicators. These indicators focus mainly on operational performance, but some of them also address organisational and safety culture aspects. However, operators of hazardous installations, in particular those with limited resources and time constraints, often find it difficult to collect the large number of different safety performance indicators. Moreover, they also have difficulties with giving a meaning to the numbers and trends recorded, especially to those that should reflect a positive safety culture. In this light, the aim of this article is to address the need to monitor and assess progress on implementation of a programme to enhance safety and organisational culture. It proposes a specific process-view approach to effectiveness evaluation of organisational and safety culture indicators by means of a multi-level system in which safety processes and staff involvement in defining improvement activities are central. In this way safety becomes fully embedded in staff activities. Key members of personnel become directly involved in identifying and supplying leading indicators relating to their own daily activity and become responsible and accountable for keeping the measurement system alive. Besides use of lagging indicators, particular emphasis is placed on the importance of identifying and selecting leading indicators which can be used to drive safety performance for organisational and safety culture aspects as well.

  1. Effectiveness evaluation methodology for safety processes to enhance organisational culture in hazardous installations.

    Science.gov (United States)

    Mengolini, A; Debarberis, L

    2008-06-30

    Safety performance indicators are widely collected and used in hazardous installations. The IAEA, OECD and other international organisations have developed approaches that strongly promote deployment of safety performance indicators. These indicators focus mainly on operational performance, but some of them also address organisational and safety culture aspects. However, operators of hazardous installations, in particular those with limited resources and time constraints, often find it difficult to collect the large number of different safety performance indicators. Moreover, they also have difficulties with giving a meaning to the numbers and trends recorded, especially to those that should reflect a positive safety culture. In this light, the aim of this article is to address the need to monitor and assess progress on implementation of a programme to enhance safety and organisational culture. It proposes a specific process-view approach to effectiveness evaluation of organisational and safety culture indicators by means of a multi-level system in which safety processes and staff involvement in defining improvement activities are central. In this way safety becomes fully embedded in staff activities. Key members of personnel become directly involved in identifying and supplying leading indicators relating to their own daily activity and become responsible and accountable for keeping the measurement system alive. Besides use of lagging indicators, particular emphasis is placed on the importance of identifying and selecting leading indicators which can be used to drive safety performance for organisational and safety culture aspects as well. PMID:18241983

  2. Safety Enhancement Technologies for Airport Ramp Area Operations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has been involved in developing advanced automation systems for improving the efficiency of air-traffic operations, reducing controller workload and enhancing...

  3. Employing ionizing radiation to enhance food safety. A review

    International Nuclear Information System (INIS)

    Food irradiation is employed to ensure food safety or food sterility, extend its shelf-life and reduce the losses due to sprouting, ripening or pests. In the Czech Republic mainly spices, mixed spices and dried vegetables are exposed to ionizing radiation. The leading suppliers of irradiated foodstuffs in Europe are Belgium, France and the Netherlands. In the USA, food irradiation is more common and there are also attempts to enforce irradiation not only for food safety, but also for technological purposes. Even though irradiation is a prospective technology, its application causes physico-chemical changes that may affect nutritional adequacy and sensory characteristics of irradiated food. In this paper, the chemical changes of basic food components (proteins, saccharides, fats) are reviewed. Some chemical changes lead to the formation of radiolytic products whose risks are still subject of scientific research. It is expected that the main use of gamma irradiation will be the treatment of diets for patients suffering from different disorders of the immune system, allergic patients or for the army and space flights. Irradiation may be a critical control point in the production of some types of foodstuffs

  4. Development of reliability-based safety enhancement technology

    International Nuclear Information System (INIS)

    This project aims to develop critical technologies and the necessary reliability DB for maximizing the economics in the NPP operation with keeping the safety using the information of the risk (or reliability). For the research goal, firstly the four critical technologies(Risk Informed Tech. Spec. Optimization, Risk Informed Inservice Testing, On-line Maintenance, Maintenance Rule) for RIR and A have been developed. Secondly, KIND (Korea Information System for Nuclear Reliability Data) has been developed. Using KIND, YGN 3,4 and UCN 3,4 component reliability DB have been established. A reactor trip history DB for all NPP in Korea also has been developed and analyzed. Finally, a detailed reliability analysis of RPS/ESFAS for KNSP has been performed. With the result of the analysis, the sensitivity analysis also has been performed to optimize the AOT/STI of tech. spec. A statistical analysis procedure and computer code have been developed for the set point drift analysis

  5. Enhancement of flame development by microwave-assisted spark ignition in constant volume combustion chamber

    KAUST Repository

    Wolk, Benjamin

    2013-07-01

    The enhancement of laminar flame development using microwave-assisted spark ignition has been investigated for methane-air mixtures at a range of initial pressures and equivalence ratios in a 1.45. l constant volume combustion chamber. Microwave enhancement was evaluated on the basis of several parameters including flame development time (FDT) (time for 0-10% of total net heat release), flame rise time (FRT) (time for 10-90% of total net heat release), total net heat release, flame kernel growth rate, flame kernel size, and ignitability limit extension. Compared to a capacitive discharge spark, microwave-assisted spark ignition extended the lean and rich ignition limits at all pressures investigated (1.08-7.22. bar). The addition of microwaves to a capacitive discharge spark reduced FDT and increased the flame kernel size for all equivalence ratios tested and resulted in increases in the spatial flame speed for sufficiently lean flames. Flame enhancement is believed to be caused by (1) a non-thermal chemical kinetic enhancement from energy deposition to free electrons in the flame front and (2) induced flame wrinkling from excitation of flame (plasma) instability. The enhancement of flame development by microwaves diminishes as the initial pressure of the mixture increases, with negligible flame enhancement observed above 3. bar. © 2013 The Combustion Institute.

  6. Evaluation of an educational intervention using the enhanced food safety cost-of-illness model.

    Science.gov (United States)

    Scharff, Robert L; McDowell, Joyce; Medeiros, Lydia

    2009-01-01

    In recent years, a number of federally sponsored state-based food safety education programs have conducted economic evaluations aimed at demonstrating the efficacy of their approaches. These evaluations have typically been based on the "Virginia method," a comprehensive, but overly simplistic means of estimating benefit-cost ratios for food safety and nutrition education programs. In this article, we use the enhanced food safety cost-of-illness model, coupled with a more complete food safety education intervention model to evaluate the efficacy of the Ohio Family Nutrition Program. We find that, under most reasonable assumptions, the derived benefit-cost ratios imply that this program is socially beneficial. The model presented here is of particular use because it can be replicated to evaluate other broad-based food safety programs.

  7. Enhancing the NASA Expendable Launch Vehicle Payload Safety Review Process Through Program Activities

    Science.gov (United States)

    Palo, Thomas E.

    2007-01-01

    The safety review process for NASA spacecraft flown on Expendable Launch Vehicles (ELVs) has been guided by NASA-STD 8719.8, Expendable Launch Vehicle Payload Safety Review Process Standard. The standard focused primarily on the safety approval required to begin pre-launch processing at the launch site. Subsequent changes in the contractual, technical, and operational aspects of payload processing, combined with lessons-learned supported a need for the reassessment of the standard. This has resulted in the formation of a NASA ELV Payload Safety Program. This program has been working to address the programmatic issues that will enhance and supplement the existing process, while continuing to ensure the safety of ELV payload activities.

  8. The development and enhancement of safety culture within an evolving organization

    International Nuclear Information System (INIS)

    The paper discusses the use of the knowledge gained from reviewing safety culture and conducting attitude surveys. The review of past safety performance and measures taken to improve is also discussed. The findings from the safety attitude survey conducted on the Sellafield Site in 1991 , provided BNFL management with information to confirm that the changes to the way safety was being managed were broadly correct, and that the commitment of BNFL to total quality management was the correct strategy for improvement of safety. It also provided the opportunity for management to think about safety as part of the management process, rather than as a separate specialist subject or part of nuclear design engineering. Local Safety Culture Review were conducted, paying attention to the area's sub-culture, how it interacts within the site, identifies its cultural strengths and weaknesses, whilst at the same time involving the management and workforce, aiding them to recognize their own organisation. Recommendations were then be written which the plant/department managers agreed with, owned and were fully committed to implementing. The difficulty of changing attitudes and culture should not be underestimated. The paper concludes that the direct involvement of the workforce and management, with full control over the development and performance of actions required to improve safety culture is vital to the success of the change process. It is important to fit the solutions to the culture under development to gain improvement, and only by demonstrating benefit to the workforce an the changes/enhancements be maintained. (author)

  9. Implementation of an Enhanced Measurement Control Program for handling nuclear safety samples at WSRC

    International Nuclear Information System (INIS)

    In the separation and purification of nuclear material, nuclear criticality safety (NCS) is of primary concern. The primary nuclear criticality safety controls utilized by the Savannah River Site (SRS) Separations Facilities involve administrative and process equipment controls. Additional assurance of NCS is obtained by identifying key process hold points where sampling is used to independently verify the effectiveness of production control. Nuclear safety measurements of samples from these key process locations provide a high degree of assurance that processing conditions are within administrative and procedural nuclear safety controls. An enhanced procedure management system aimed at making improvements in the quality, safety, and conduct of operation was implemented for Nuclear Safety Sample (NSS) receipt, analysis, and reporting. All procedures with nuclear safety implications were reviewed for accuracy and adequate detail to perform the analytical measurements safely, efficiently, and with the utmost quality. Laboratory personnel worked in a ''Deliberate Operating'' mode (a systematic process requiring continuous expert oversight during all phases of training, testing, and implementation) to initiate the upgrades. Thus, the effort to revise and review nuclear safety sample procedures involved a team comprised of a supervisor, chemist, and two technicians for each procedure. Each NSS procedure was upgraded to a ''Use Every Time'' (UET) procedure with sign-off steps to ensure compliance with each step for every nuclear safety sample analyzed. The upgrade program met and exceeded both the long and short term customer needs by improving measurement reliability, providing objective evidence of rigid adherence to program principles and requirements, and enhancing the system for independent verification of representative sampling from designated NCS points

  10. NASA Engineering and Safety Center (NESC) Enhanced Melamine (ML) Foam Acoustic Test (NEMFAT)

    Science.gov (United States)

    McNelis, Anne M.; Hughes, William O.; McNelis, Mark E.

    2014-01-01

    The NASA Engineering and Safety Center (NESC) funded a proposal to achieve initial basic acoustic characterization of ML (melamine) foam, which could serve as a starting point for a future, more comprehensive acoustic test program for ML foam. A project plan was developed and implemented to obtain acoustic test data for both normal and enhanced ML foam. This project became known as the NESC Enhanced Melamine Foam Acoustic Test (NEMFAT). This document contains the outcome of the NEMFAT project.

  11. Split-intron retroviral vectors: enhanced expression with improved safety.

    Science.gov (United States)

    Ismail, S I; Kingsman, S M; Kingsman, A J; Uden, M

    2000-03-01

    The inclusion of retrovirus-derived introns within retrovirus-based expression vectors leads to a fraction of the resulting transcripts being spliced. Such splicing has been shown to markedly improve expression (W. J. Krall et al., Gene Ther. 3:37-48, 1996). One way to improve upon this still further might involve the use of more efficient introns instead of those from the provirus. Currently, however, incorporation of such introns remains self-defeating since they are removed in the nucleus of the producer cell. In the past, elaborate ways to overcome this problem have included the use of alphaviruses to make the vector transcripts within the cytoplasm, thus avoiding the nuclear splicing machinery during vector production (K. J. Li and H. Garoff, Proc. Natl. Acad. Sci. USA 95:3650-3654, 1998). We now present a novel design for the inclusion of introns within a retroviral vector. In essence, this is achieved by exploiting the retroviral replication process to copy not only the U3 promoter but also a synthetic splice donor to the 5'-long-terminal-repeat position during reverse transcription. Once copied, synthesized transcripts then contain a splice donor at their 5' end capable of interacting with a consensus splice acceptor engineered downstream of the packaging signal. Upon transduction, we demonstrate these vectors to produce enhanced expression from near fully spliced (and thus packaging signal minus) transcripts. The unique design of these high titer and high-expression retroviral vectors may be of use in a number of gene therapy applications. PMID:10666267

  12. Enhanced denitrification of Pseudomonas stutzeri by a bioelectrochemical system assisted with solid-phase humin.

    Science.gov (United States)

    Xiao, Zhixing; Awata, Takanori; Zhang, Dongdong; Zhang, Chunfang; Li, Zhiling; Katayama, Arata

    2016-07-01

    The denitrification reactions performed by Pseudomonas stutzeri JCM20778 were enhanced electrochemically with the use of solid-phase humin, although P. stutzeri itself was incapable of receiving electrons directly from the graphite electrode. Electrochemically reduced humin enhanced the microbial, but not abiotic, denitrification reactions. Electric current and cyclic voltammetry analyses suggested that the solid-phase humin functioned as an electron donor for the denitrification reactions of P. stutzeri. Nitrogen balance study and the estimation of the first-order rate constants of the consecutive denitrification reactions suggested that the solid-phase humin enhanced all reducing reactions from nitrate to nitrogen gas. Considering the wide distribution of humin in the environment, the findings that solid-phase humin can assist in electron transfer, from the electrode to a denitrifying bacterium that has little ability to directly utilize external electrons, has important implications for the widespread application of bioelectrochemical systems assisted by solid-phase humin for enhancing microbial denitrification.

  13. Postharvest intervention technologies for safety enhancement of meat and meat based products; a critical review.

    Science.gov (United States)

    Sohaib, Muhammad; Anjum, Faqir Muhammad; Arshad, Muhammad Sajid; Rahman, Ubaid Ur

    2016-01-01

    Globally, the demand for safe, healthy and nutritious meat and allied products possesses improved taste with extended shelf life is mounting. Microbial safety is among the imperative challenges that prevails in meat products because they provide an ideal medium for the growth of microorganisms particularly pathogenic bacteria. The incidence of these microbes can result quality deterioration of products leading towards food borne diseases when consumed by peoples. Several preservation technologies like chemical and biological interventions are effective to retard or inactivate the growth of micro-organisms most commonly related to food-borne diseases. Despite these, innovative approaches like hydrostatic pressure processing, active packaging, pulse electric field, hurdle approach and use of natural antimicrobials can be deployed to enhance the safety of meat and meat products. The objective of review is to describe the current approaches and developing technologies for enhancing safety of meat and allied meat products. PMID:26787929

  14. Development of an algorithm for using weather-dependent dynamic speed limits to enhance safety

    NARCIS (Netherlands)

    Jonkers, E.; Klunder, G.; Horst, A.R.A. van der; Rooy, R. de

    2008-01-01

    This paper describes an ongoing research project in the Netherlands for lowering the speed limit, depending on the weather condition (in particular rain) to enhance traffic safety. The research in this project consists of three main parts. In the first part, research has been conducted on the strate

  15. Microwave Assisted Alkali Pretreatment of Rice Straw for Enhancing Enzymatic Digestibility

    Directory of Open Access Journals (Sweden)

    Renu Singh

    2014-01-01

    Full Text Available Rapid industrialization, increasing energy demand, and climate change are the conditions that forced the researchers to develop a clean, efficient, renewable, and sustainable source of energy which has a potential to replace fossil fuels. Ethanol is one of the attractive and suitable renewable energy resources. In present study, effectiveness of microwave pretreatment in combination with sodium hydroxide (NaOH for increasing enzymatic hydrolysis of rice straw has been investigated and under optimum conditions obtained a maximum reducing sugar (1334.79 µg/mL through microwave assisted NaOH pretreatment. Chemical composition analysis and scanning electron microscope (SEM images showed that the removal of lignin, hemicellulose, and silicon content is more in microwave assisted NaOH pretreatment than the blank sample. X-ray diffraction (XRD analysis revealed that the crystallinity index of rice straw treated with microwave assisted alkali (54.55% is significantly high as compared to the blank (49.07%. Hence, the present study proves that microwave assisted alkali pretreatment can effectively enhance enzymatic digestibility of rice straw and it is feasible to convert rice straw for bioethanol production.

  16. Quantum path control using attosecond pulse trains via UV-assisted resonance enhance ionization

    Institute of Scientific and Technical Information of China (English)

    李芳; 魏来; 何志聪

    2015-01-01

    We theoretically investigate the quantum path selection in an ultraviolet (UV)-assisted near-infrared field with an UV energy below the ionization threshold. By calculating the ionization probability with different assistant UV frequencies, we find that a resonance-enhanced ionization peak emerges in the region Euv

  17. An Approach to Enhancement of the Safety Culture of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yong Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The culture of an organization is very complex to study and evaluate, but it is possible to examine the specific norms that figure out the culture for the safety of a system. This paper describes an initiation plan to study the safety culture issue in Korean NPPs. Recently there happened successively events that turned out to be socially prominent in Korea. Many issues on the safety culture aspect of NPPs have been raised including the types of errors such as violations, an intended concealment of safety-related information, counterfeit items, forgery process in procurement, and so on. Those were investigated in detail for the root causes of these issues as human and organizational errors and for the countermeasures to prevent those events. They are integrated into a correspondent long-term plan including the establishment of a fundamental infrastructure of safety culture management for operating NPPs in Korea. A monitoring system with analysis functions utilizing system dynamics simulation and data mining is proposed to be incorporated into a safety culture management system. Additionally, a set of training and support programs are to be developed for the enhancement of some selected competence of the operating personnel in Korean NPPs. The safe operation of NPPs requires the typical safety culture characteristics of the high reliability organization (HRO). The culture of an organization is very complex to study and evaluate, but it is possible to examine the specific norms that figure out the culture for the safety of a system. This paper describes an integrated systems approach as an initiating plan to study the safety culture issue in Korean NPPs.

  18. An Approach to Enhancement of the Safety Culture of Nuclear Power Plants

    International Nuclear Information System (INIS)

    The culture of an organization is very complex to study and evaluate, but it is possible to examine the specific norms that figure out the culture for the safety of a system. This paper describes an initiation plan to study the safety culture issue in Korean NPPs. Recently there happened successively events that turned out to be socially prominent in Korea. Many issues on the safety culture aspect of NPPs have been raised including the types of errors such as violations, an intended concealment of safety-related information, counterfeit items, forgery process in procurement, and so on. Those were investigated in detail for the root causes of these issues as human and organizational errors and for the countermeasures to prevent those events. They are integrated into a correspondent long-term plan including the establishment of a fundamental infrastructure of safety culture management for operating NPPs in Korea. A monitoring system with analysis functions utilizing system dynamics simulation and data mining is proposed to be incorporated into a safety culture management system. Additionally, a set of training and support programs are to be developed for the enhancement of some selected competence of the operating personnel in Korean NPPs. The safe operation of NPPs requires the typical safety culture characteristics of the high reliability organization (HRO). The culture of an organization is very complex to study and evaluate, but it is possible to examine the specific norms that figure out the culture for the safety of a system. This paper describes an integrated systems approach as an initiating plan to study the safety culture issue in Korean NPPs

  19. 75 FR 73014 - Notice of Public Meeting: Updating the Flight Instructor Renewal Process To Enhance Safety of Flight

    Science.gov (United States)

    2010-11-29

    ... Federal Aviation Administration 14 CFR Part 61 Notice of Public Meeting: Updating the Flight Instructor Renewal Process To Enhance Safety of Flight AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... to improve the Certificated Flight Instructor (CFI) biennial renewal process to enhance the safety...

  20. 76 FR 6087 - Draft Weapons Safety Assessment on the Use of Enhanced Weapons; Notice of Availability and...

    Science.gov (United States)

    2011-02-03

    ... COMMISSION 10 CFR Part 73 RIN 3150-AI49 Draft Weapons Safety Assessment on the Use of Enhanced Weapons... guidance document entitled ``Weapons Safety Assessment'' (WSA). This guidance would be used by licensees and certificate holders applying to the NRC to obtain enhanced weapons under the NRC's proposed...

  1. ASME Nuclear Crane Standards for Enhanced Crane Safety and Increased Profit

    Science.gov (United States)

    Parkhurst, Stephen N.

    2000-01-01

    The ASME NOG-1 standard, 'Rules for Construction of Overhead and Gantry Cranes', covers top running cranes for nuclear facilities; with the ASME NUM-1 standard, 'Rules for Construction of Cranes, Monorails, and Hoists', covering the single girder, underhung, wall and jib cranes, as well as the monorails and hoists. These two ASME nuclear crane standards provide criteria for designing, inspecting and testing overhead handling equipment with enhanced safety to meet the 'defense-in-depth' approach of the United States Nuclear Regulatory Commission (USNRC) documents NUREG 0554 and NUREG 0612. In addition to providing designs for enhanced safety, the ASME nuclear crane standards provide a basis for purchasing overhead handling equipment with standard safety features, based upon accepted engineering principles, and including performance and environmental parameters specific to nuclear facilities. The ASME NOG-1 and ASME NUM-1 standards not only provide enhanced safety for handling a critical load, but also increase profit by minimizing the possibility of load drops, by reducing cumbersome operating restrictions, and by providing the foundation for a sound licensing position. The ASME nuclear crane standards can also increase profit by providing the designs and information to help ensure that the right standard equipment is purchased. Additionally, the ASME nuclear crane standards can increase profit by providing designs and information to help address current issues, such as the qualification of nuclear plant cranes for making 'planned engineered lifts' for steam generator replacement and decommissioning.

  2. Mutual Information-Assisted Wavelet Function Selection for Enhanced Rolling Bearing Fault Diagnosis

    Directory of Open Access Journals (Sweden)

    Ruqiang Yan

    2015-01-01

    Full Text Available This paper presents an enhanced rolling bearing fault diagnosis approach, based on optimized wavelet packet transform (WPT assisted with quantitative wavelet function selection. Mutual information is utilized as a quantitative measure to select the most suitable wavelet function for the WPT-based vibration analysis. Energy features from coefficients of an optimal set of orthogonal wavelet subspaces which resulted from the WPT-based vibration analysis are input to different classifiers. The fault states of the rolling bearings can then be identified. Experiment studies conducted on a rolling bearing test system have verified the effectiveness of the proposed approach for rolling bearing fault diagnosis.

  3. Reliability prediction for the vehicles equipped with advanced driver assistance systems (ADAS and passive safety systems (PSS

    Directory of Open Access Journals (Sweden)

    Balbir S. Dhillon

    2012-10-01

    Full Text Available The human error has been reported as a major root cause in road accidents in today’s world. The human as a driver in road vehicles composed of human, mechanical and electrical components is constantly exposed to changing surroundings (e.g., road conditions, environmentwhich deteriorate the driver’s capacities leading to a potential accident. The auto industries and transportation authorities have realized that similar to other complex and safety sensitive transportation systems, the road vehicles need to rely on both advanced technologies (i.e., Advanced Driver Assistance Systems (ADAS and Passive Safety Systems (PSS (e.g.,, seatbelts, airbags in order to mitigate the risk of accidents and casualties. In this study, the advantages and disadvantages of ADAS as active safety systems as well as passive safety systems in road vehicles have been discussed. Also, this study proposes models that analyze the interactions between human as a driver and ADAS Warning and Crash Avoidance Systems and PSS in the design of vehicles. Thereafter, the mathematical models have been developed to make reliability prediction at any given time on the road transportation for vehicles equipped with ADAS and PSS. Finally, the implications of this study in the improvement of vehicle designs and prevention of casualties are discussed.

  4. Energy systems programs funded by the Assistant Secretary for Environment, Safety and Health: FY 1993--FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Buttram, A.W. [ed.

    1994-12-31

    This document presents an overview of work at Martin Marietta Energy Systems, Inc., (Energy Systems) during FY 1993--FY 1994 that was funded by the Department of Energy`s (DOE`s) Assistant Secretary for Environment, Safety and Health (ASEH). To illustrate the programmatic breadth of Energy Systems and to establish the context within which this work was accomplished, this document also includes representative descriptions of ASEH-related work at Energy Systems done for other sponsors. Activities for ASEH cover a wide variety of subjects that are geared towards the environmental, safety, and health aspects of DOE operations. Subjects include the following: environmental compliance, environmental guidance, environmental audits, NEPA oversight, epidemiology and health surveillance, transportation and packaging safety, safety and quality assurance; technical standards, performance indicators, occurrence reporting, health physics instrumentation, risk management, security evaluations, and medical programs. The technical support section describes work in progress for ASEH, including specific program accomplishments. The work for others section describes work for non-ASEH sponsors that reinforces and supplements the ASEH work. Appendix A includes a list of FY 1993--FY 1994 publications related to the ASEH work.

  5. Enhancement of the crystalline Ge film growth by inductively coupled plasma-assisted pulsed DC sputtering.

    Science.gov (United States)

    Kim, Eunkyeom; Han, Seung-Hee

    2014-11-01

    The effect of pulsed DC sputtering on the crystalline growth of Ge thin film was investigated. Ge thin films were deposited on the glass substrates using ICP-assisted pulsed DC sputtering. The Ge target was sputtered using asymmetric bipolar pulsed DC sputtering system with and without assistance of ICP source. The pulse frequency of 200 Hz and the pulse on time of 500 μsec (duty cycle = 10%) were kept during sputtering process. Crystal structures were studied from X-ray diffraction. The X-ray diffraction patterns clearly showed crystalline film structures. The Ge thin films with randomly oriented crystalline were obtained using pulsed DC sputtering without ICP, whereas they had well aligned (220) orientation crystalline using ICP source. Moreover, the combination of ICP assistance and pulsed DC sputtering enhanced the growth of crystalline Ge thin films without hydrogen and metal by in situ deposition. The structure and lattice of the films were studied from TEM images. The cross-sectional TEM images revealed the deposited Ge films with columnar structure.

  6. A multimodal imaging framework for enhanced robot-assisted partial nephrectomy guidance

    Science.gov (United States)

    Halter, Ryan J.; Wu, Xiaotian; Hartov, Alex; Seigne, John; Khan, Shadab

    2015-03-01

    Robot-assisted laparoscopic partial nephrectomies (RALPN) are performed to treat patients with locally confined renal carcinoma. There are well-documented benefits to performing partial (opposed to radical) kidney resections and to using robot-assisted laparoscopic (opposed to open) approaches. However, there are challenges in identifying tumor margins and critical benign structures including blood vessels and collecting systems during current RALPN procedures. The primary objective of this effort is to couple multiple image and data streams together to augment visual information currently provided to surgeons performing RALPN and ultimately ensure complete tumor resection and minimal damage to functional structures (i.e. renal vasculature and collecting systems). To meet this challenge we have developed a framework and performed initial feasibility experiments to couple pre-operative high-resolution anatomic images with intraoperative MRI, ultrasound (US) and optical-based surface mapping and kidney tracking. With these registered images and data streams, we aim to overlay the high-resolution contrast-enhanced anatomic (CT or MR) images onto the surgeon's view screen for enhanced guidance. To date we have integrated the following components of our framework: 1) a method for tracking an intraoperative US probe to extract the kidney surface and a set of embedded kidney markers, 2) a method for co-registering intraoperative US scans with pre-operative MR scans, and 3) a method for deforming pre-op scans to match intraoperative scans. These components have been evaluated through phantom studies to demonstrate protocol feasibility.

  7. The Norwegian Assistance Program for Increased Reactor Safety in Eastern Europe

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, E.; Saxeboel, G.

    2002-06-01

    For several years Norway has focused on issues related to international nuclear safety. Consequently, under the Norwegian Plan of Action for Nuclear Safety, Norwegian governmental authorities have been actively involved in bilateral co-operation efforts to improve safety at Kola Nuclear Power Plant, Leningrad Nuclear Power Plant and Ignalina Nuclear Power Plant. Norway's major involvement began in 1993 at the Kola NPP, and has included projects within several different areas of nuclear safety with a total budget of 124 million NOK. In this report, the projects have been grouped as follows (UD- 1999): (1) Reliability of core cooling and emergency power supply; (2) Component reliability and primary circuit reliability; (3) Improved instrumentation and control; (4) Operational safety; (5) Safety studies. The involvement in Ignalina and Leningrad NPP started 1996 and 1997, respectively. The accumulated budget for the Norwegian efforts at Leningrad NPP is 13.8 million NOK with focus on the following two areas: (1) Training of personnel and prevention of human error; (2) Component reliability and primary circuit integrity. The Norwegian monetary contribution related to projects at lgnalina NPP is 11 million NOK, with main efforts dedicated to the following two areas: (1) Security and physical protection of the plant; (2) Fire safety. In the early phase of the projects, difficulties were encountered concerning tax exemption and indemnity for the delivery of equipment to Kola NPP. Matters improved successively, following the signing of the Norwegian-Russian Framework Agreement in 1998. Another positive change is the involvement of Russian contractors, who now contribute to the supply of considerable parts of the equipment and services and give a tighter co-operation between Russian and Western suppliers. The feedback from the beneficiaries has generally been positive throughout the project periods. (author)

  8. SAFETY

    CERN Multimedia

    Niels Dupont

    2013-01-01

    CERN Safety rules and Radiation Protection at CMS The CERN Safety rules are defined by the Occupational Health & Safety and Environmental Protection Unit (HSE Unit), CERN’s institutional authority and central Safety organ attached to the Director General. In particular the Radiation Protection group (DGS-RP1) ensures that personnel on the CERN sites and the public are protected from potentially harmful effects of ionising radiation linked to CERN activities. The RP Group fulfils its mandate in collaboration with the CERN departments owning or operating sources of ionising radiation and having the responsibility for Radiation Safety of these sources. The specific responsibilities concerning "Radiation Safety" and "Radiation Protection" are delegated as follows: Radiation Safety is the responsibility of every CERN Department owning radiation sources or using radiation sources put at its disposition. These Departments are in charge of implementing the requi...

  9. Driver assistance - Firstly a contribution to primary safety or rather to comfort?; Fahrerassistenz primaer zum Komfort oder fuer die Sicherheit?

    Energy Technology Data Exchange (ETDEWEB)

    Bubb, H. [TU Muenchen, Garching (Germany). Lehrstuhl fuer Ergonomie

    2003-07-01

    Doubtless assistance systems should contribute to the safety of car driving. They support simultaneously a comfortable use of the car. Especially the operation comfort is characterised by clarity, self explaining, robustness against errors, and so on. Operation comfort doesn't give an inessential contribution to a reliable and appropriate interaction between driver and vehicle that means also a contribution to a reliable function of the total system and thereby to safety. Therefore the subjective experience of assistance systems is of excellent importance with view on the subjective and public confidence in new assistance systems. Are they seen rather as a gain of comfort, as it is preferred by the producer by reasons of production related liability, or as an easing of the driver's behaviour providing safety? Consists in the last called tendency a new kind of danger? In this connection juristic problems may not be unmentioned. The driver may not or not completely be called to account for procedures on which he has no influence or thinks to have no influence. In this case the account for the not compensated damage is contributed to the producer of the system. Therefore, by considering human characteristics and abilities of the driver during the development of assistance systems unwanted juristic consequences should be prevented. (orig.) [German] Assitenzsysteme sollen zweifellos einen Beitrag fuer die Sicherheit des Autofahrers liefern. Zugleich dienen sie aber auch fuer eine komfortable Nutzung des Fahrzeugs. Speziell der Bedienkomfort ist durch leichte Verstaendlichkeit, Selbsterklaerbarkeit, Fehlerrobustheit u.ae. charakterisiert. Durch ihn wird ein nicht unwesentlicher Beitrag zur sicheren und zweckdienlichen Interaktion zwischen Fahrer und Fahrzeug geleistet, also auch ein Beitrag fuer die zuverlaessige Funktion des Systems und damit fuer die Sicherheit. Von herausragender Bedeutung insbesondere im Hinblick auf das subjektive und das oeffentliche

  10. Enhancing Food Safety and Productivity: Technology Use in the Canadian Food Processing Industry

    OpenAIRE

    Sabourin, David; Baldwin, John R.

    2002-01-01

    This paper examines the factors contributing to the adoption of advanced technologies in the Canadian food-processing sector. The numbers of technologies used by a plant is found to be highly correlated with expected gains in firm performance. The benefits of enhanced food safety and quality, as well as productivity improvements, are closely associated with technology use. Impediments that negatively affect technology use include software costs, problems with external financing, lack of cash ...

  11. Short-term initiatives for enhancing cyber-safety within South African schools

    Directory of Open Access Journals (Sweden)

    Elmarie Kritzinger

    2016-07-01

    Full Text Available The rate of technological development across the globe is dramatic. The decreasing cost and increasing availability of ICT devices means that its users are no longer exclusively industry or government employees – they are now also home users. Home users integrate ICT in their daily lives for education, socialising and information gathering. However, using ICT is associated with risks and threats, such as identity theft and phishing scams. Most home users of ICT do not have the necessary information technology and Internet skills to protect themselves and their information. School learners, in particular, are not sufficiently educated on how to use technological devices safely, especially in developing countries such as South Africa. The national school curriculum in South Africa currently does not make provision for cyber-safety education, and the availability of supporting material and training for ICT teachers in South Africa is limited, resulting in a lack of knowledge and skills regarding cyber-safety. The research in hand focuses on the situation concerning cyber-safety awareness in schools and has adopted a short-term approach towards cyber-safety among teachers and school learners in South Africa until a formal long-term national approach has been implemented. This study takes a quantitative approach to investigating the current options of teachers to enhance cyber-safety among learners in their schools. The research proposes that short-term initiatives (i.e. posters can increase learners’ awareness of cyber-safety until formal cyber-safety awareness methods have been introduced.

  12. Trending of low level events and near misses to enhance safety performance in nuclear power plants

    International Nuclear Information System (INIS)

    The IAEA Safety Fundamentals publication, Safety of Nuclear Installations, Safety Series No. 110, states the need for operating organizations to establish a programme for the collection and analysis of operating experience in nuclear power plants. Such a programme ensures that operating experience is analysed, events important to safety are reviewed in depth, and lessons learned are disseminated to the staff of the organization and to relevant national and international organizations. As a result of the effort to enhance safety in operating organizations, incidents are progressively decreasing in number and significance. This means that in accordance with international reporting requirements the amount of collected data becomes less sufficient to draw meaningful statistical conclusions. This is where the collection and trend analysis of low level events and near misses can prove to be very useful. These trends can show which of the safety barriers are weak or failing more frequently. Evaluation and trending of low level events and near misses will help to prevent major incidents because latent weaknesses have been identified and corrective actions taken to prevent recurrence. This leads to improved safety and production. Low level events and near misses, which may reach several thousand per reactor operating year, need to be treated by the organizations as learning opportunities. A system for capturing these low level events and near misses truly needs to be an organization-wide system in which all levels of the organization, including contractors, participate. It is desirable that the overall operational experience feedback (OEF) process should integrate the lessons learned and the associated data from significant events with those of lower level events and near misses. To be able to effectively implement a process dealing with low level events and near misses, it is necessary that the organization have a well established OEF process for significant events

  13. Safety

    CERN Multimedia

    2003-01-01

    Please note that the safety codes A9, A10 AND A11 (ex annexes of SAPOCO/42) entitled respectively "Safety responsibilities in the divisions" "The safety policy committee (SAPOCO) and safety officers' committees" and "Administrative procedure following a serious accident or incident" are available on the web at the following URLs: Code A9: http://edms.cern.ch/document/337016/LAST_RELEASED Code A10: http://edms.cern.ch/document/337019/LAST_RELEASED Code A11: http://edms.cern.ch/document/337026/LAST_RELEASED Paper copies can also be obtained from the TIS divisional secretariat, e-mail: tis.secretariat@cern.ch. TIS Secretariat

  14. Enhancement and electric charge-assisted tuning of nonlinear light generation in bipolar plasmonics.

    Science.gov (United States)

    Ding, Wei; Zhou, Liangcheng; Chou, Stephen Y

    2014-05-14

    We propose and experimentally demonstrate a new plasmonic nonlinear light generation (NLG) structure, termed plasmonic-enhanced, charge-assisted second-harmonic generator (p-CASH), that not only achieves high second-harmonic generation (SHG) enhancement (76-fold), large SHG tunability by bias (8%/V), wide tuning range (280%), 7.8 × 10(-9) conversion efficiency, and high stability but also exhibits a SHG tuning, that is bipolar rather than unipolar, not due to the third-order nonlinear polarization term, hence fundamentally different from the classic electric field induced SHG-tuning (EFISH). We propose a new SHG tuning mechanism: the second-order nonlinear polarization term enhanced by plasmonic effects, changed by charge injection and negative oxygen vacancies movement, and is nearly 3 orders of magnitude larger than EFISH. p-CASH is a bipolar parallel-plate capacitor with thin layers of plasmonic nanostructures, a TiOx (semiconductor and nonlinear) and a SiO2 (insulator) sandwiched between two electrodes. Fabrication of p-CASH used nanoimprint on 4″ wafer and is scalable to wallpaper-sized areas. The new structure, new properties, and new understanding should open up various new designs and applications of NLG in various fields.

  15. Enhancement and electric charge-assisted tuning of nonlinear light generation in bipolar plasmonics.

    Science.gov (United States)

    Ding, Wei; Zhou, Liangcheng; Chou, Stephen Y

    2014-05-14

    We propose and experimentally demonstrate a new plasmonic nonlinear light generation (NLG) structure, termed plasmonic-enhanced, charge-assisted second-harmonic generator (p-CASH), that not only achieves high second-harmonic generation (SHG) enhancement (76-fold), large SHG tunability by bias (8%/V), wide tuning range (280%), 7.8 × 10(-9) conversion efficiency, and high stability but also exhibits a SHG tuning, that is bipolar rather than unipolar, not due to the third-order nonlinear polarization term, hence fundamentally different from the classic electric field induced SHG-tuning (EFISH). We propose a new SHG tuning mechanism: the second-order nonlinear polarization term enhanced by plasmonic effects, changed by charge injection and negative oxygen vacancies movement, and is nearly 3 orders of magnitude larger than EFISH. p-CASH is a bipolar parallel-plate capacitor with thin layers of plasmonic nanostructures, a TiOx (semiconductor and nonlinear) and a SiO2 (insulator) sandwiched between two electrodes. Fabrication of p-CASH used nanoimprint on 4″ wafer and is scalable to wallpaper-sized areas. The new structure, new properties, and new understanding should open up various new designs and applications of NLG in various fields. PMID:24730390

  16. Safety Nets or Trampolines? Federal Crop Insurance, Disaster Assistance, and the Farm Bill

    OpenAIRE

    Goodwin, Barry K.; Rejesus, Roderick M.

    2008-01-01

    We review the implications of the 2007 Farm Bill for the risk management dimensions of U.S. agriculture and policy. Legislative proposals suggest significant changes in risk management policy, including the introduction of state or national revenue insurance. We also pursue an empirical analysis of the interrelationships of crop insurance, disaster relief, and farm profitability. We find an inverse relationship between disaster assistance and insurance purchases. Our analysis also suggests th...

  17. Enhanced adhesion of Cu-W thin films by ion beam assisting bombardment implanting

    Institute of Scientific and Technical Information of China (English)

    ZHOU Ling-ping; WANG Ming-pu; WANG Rui; LI Zhou; ZHU Jia-jun; PENG Kun; LI De-yi; LI Shao-lu

    2008-01-01

    Cu-W thin film with high W content was deposited by dual-target DC-magnetron co-sputtering technology. Effects of the substrates surface treating technique on the adhesive strength of Cu-W thin films were studied. It is found that the technique of ion beam assisting bombardment implanting of W particles can remarkably improve the adhesive property of Cu-W thin films. Indentation and scratching test show that, the critical load is doubled over than the sample only sputter-cleaned by ion beam. The enhancing mechanism of ion beam assisting bombardment implanting of Cu-W thin films was analyzed. With the help of mid-energy Ar+ ion beam, W atoms can diffuse into the Fe-substrate surface layer; Fe atoms in the substrate surface layer and W atoms interlace with one another; and microcosmic mechanical meshing and diffusing combination on atom-scale among the Fe and W atoms through the film/substrate interface can be formed. The wettability and thermal expansion properties of the W atoms diffusion zone containing plentiful W atoms are close to those of pure W or W-based Cu-W film.

  18. Enhanced Properties of Porous GaN Prepared by UV Assisted Electrochemical Etching

    International Nuclear Information System (INIS)

    The structural and optical properties of porous GaN films on sapphire (0001) prepared by UV assisted electrochemical etching were reported in this study. SEM micrographs indicated that the shapes of the pores for both porous samples are nearly hexagonal. XRD revealed that the broadening in spectrum is due to the small size crystallites. As compared to the as grown GaN films, porous layers exhibit a substantial photoluminescence (PL) intensity enhancement with red-shifted band-edge PL peaks associated with the relaxation of compressive stress. The shift of E2(high) to the lower frequency in Raman spectra of the porous GaN films further confirms such a stress relaxation. (author)

  19. Volume-assisted estimation of liver function based on Gd-EOB-DTPA-enhanced MR relaxometry

    Energy Technology Data Exchange (ETDEWEB)

    Haimerl, Michael; Schlabeck, Mona; Verloh, Niklas; Fellner, Claudia; Stroszczynski, Christian; Wiggermann, Philipp [University Hospital Regensburg, Department of Radiology, Regensburg (Germany); Zeman, Florian [University Hospital Regensburg, Center for Clinical Trials, Regensburg (Germany); Nickel, Dominik [MR Applications Development, Siemens AG, Healthcare Sector, Erlangen (Germany); Barreiros, Ana Paula [University Hospital Regensburg, Department of Internal Medicine I, Regensburg (Germany); Loss, Martin [University Hospital Regensburg, Department of Surgery, Regensburg (Germany)

    2016-04-15

    To determine whether liver function as determined by indocyanine green (ICG) clearance can be estimated quantitatively from hepatic magnetic resonance (MR) relaxometry with gadoxetic acid (Gd-EOB-DTPA). One hundred and seven patients underwent an ICG clearance test and Gd-EOB-DTPA-enhanced MRI, including MR relaxometry at 3 Tesla. A transverse 3D VIBE sequence with an inline T1 calculation was acquired prior to and 20 minutes post-Gd-EOB-DTPA administration. The reduction rate of T1 relaxation time (rrT1) between pre- and post-contrast images and the liver volume-assisted index of T1 reduction rate (LVrrT1) were evaluated. The plasma disappearance rate of ICG (ICG-PDR) was correlated with the liver volume (LV), rrT1 and LVrrT1, providing an MRI-based estimated ICG-PDR value (ICG-PDR{sub est}). Simple linear regression model showed a significant correlation of ICG-PDR with LV (r = 0.32; p = 0.001), T1{sub post} (r = 0.65; p < 0.001) and rrT1 (r = 0.86; p < 0.001). Assessment of LV and consecutive evaluation of multiple linear regression model revealed a stronger correlation of ICG-PDR with LVrrT1 (r = 0.92; p < 0.001), allowing for the calculation of ICG-PDR{sub est}. Liver function as determined using ICG-PDR can be estimated quantitatively from Gd-EOB-DTPA-enhanced MR relaxometry. Volume-assisted MR relaxometry has a stronger correlation with liver function than does MR relaxometry. (orig.)

  20. Volume-assisted estimation of liver function based on Gd-EOB-DTPA-enhanced MR relaxometry

    International Nuclear Information System (INIS)

    To determine whether liver function as determined by indocyanine green (ICG) clearance can be estimated quantitatively from hepatic magnetic resonance (MR) relaxometry with gadoxetic acid (Gd-EOB-DTPA). One hundred and seven patients underwent an ICG clearance test and Gd-EOB-DTPA-enhanced MRI, including MR relaxometry at 3 Tesla. A transverse 3D VIBE sequence with an inline T1 calculation was acquired prior to and 20 minutes post-Gd-EOB-DTPA administration. The reduction rate of T1 relaxation time (rrT1) between pre- and post-contrast images and the liver volume-assisted index of T1 reduction rate (LVrrT1) were evaluated. The plasma disappearance rate of ICG (ICG-PDR) was correlated with the liver volume (LV), rrT1 and LVrrT1, providing an MRI-based estimated ICG-PDR value (ICG-PDRest). Simple linear regression model showed a significant correlation of ICG-PDR with LV (r = 0.32; p = 0.001), T1post (r = 0.65; p < 0.001) and rrT1 (r = 0.86; p < 0.001). Assessment of LV and consecutive evaluation of multiple linear regression model revealed a stronger correlation of ICG-PDR with LVrrT1 (r = 0.92; p < 0.001), allowing for the calculation of ICG-PDRest. Liver function as determined using ICG-PDR can be estimated quantitatively from Gd-EOB-DTPA-enhanced MR relaxometry. Volume-assisted MR relaxometry has a stronger correlation with liver function than does MR relaxometry. (orig.)

  1. A Secure ECC-based RFID Mutual Authentication Protocol to Enhance Patient Medication Safety.

    Science.gov (United States)

    Jin, Chunhua; Xu, Chunxiang; Zhang, Xiaojun; Li, Fagen

    2016-01-01

    Patient medication safety is an important issue in patient medication systems. In order to prevent medication errors, integrating Radio Frequency Identification (RFID) technology into automated patient medication systems is required in hospitals. Based on RFID technology, such systems can provide medical evidence for patients' prescriptions and medicine doses, etc. Due to the mutual authentication between the medication server and the tag, RFID authentication scheme is the best choice for automated patient medication systems. In this paper, we present a RFID mutual authentication scheme based on elliptic curve cryptography (ECC) to enhance patient medication safety. Our scheme can achieve security requirements and overcome various attacks existing in other schemes. In addition, our scheme has better performance in terms of computational cost and communication overhead. Therefore, the proposed scheme is well suitable for patient medication systems.

  2. Enhancing the Safety, Security and Resilience of ICT and Scada Systems Using Action Research

    Science.gov (United States)

    Johnsen, Stig; Skramstad, Torbjorn; Hagen, Janne

    This paper discusses the results of a questionnaire-based survey used to assess the safety, security and resilience of information and communications technology (ICT) and supervisory control and data acquisition (SCADA) systems used in the Norwegian oil and gas industry. The survey identifies several challenges, including the involvement of professionals with different backgrounds and expertise, lack of common risk perceptions, inadequate testing and integration of ICT and SCADA systems, poor information sharing related to undesirable incidents and lack of resilience in the design of technical systems. Action research is proposed as a process for addressing these challenges in a systematic manner and helping enhance the safety, security and resilience of ICT and SCADA systems used in oil and gas operations.

  3. A Secure ECC-based RFID Mutual Authentication Protocol to Enhance Patient Medication Safety.

    Science.gov (United States)

    Jin, Chunhua; Xu, Chunxiang; Zhang, Xiaojun; Li, Fagen

    2016-01-01

    Patient medication safety is an important issue in patient medication systems. In order to prevent medication errors, integrating Radio Frequency Identification (RFID) technology into automated patient medication systems is required in hospitals. Based on RFID technology, such systems can provide medical evidence for patients' prescriptions and medicine doses, etc. Due to the mutual authentication between the medication server and the tag, RFID authentication scheme is the best choice for automated patient medication systems. In this paper, we present a RFID mutual authentication scheme based on elliptic curve cryptography (ECC) to enhance patient medication safety. Our scheme can achieve security requirements and overcome various attacks existing in other schemes. In addition, our scheme has better performance in terms of computational cost and communication overhead. Therefore, the proposed scheme is well suitable for patient medication systems. PMID:26573649

  4. Approaches to enhancing radiation safety in cardiovascular imaging: a scientific statement from the American Heart Association.

    Science.gov (United States)

    Fazel, Reza; Gerber, Thomas C; Balter, Stephen; Brenner, David J; Carr, J Jeffrey; Cerqueira, Manuel D; Chen, Jersey; Einstein, Andrew J; Krumholz, Harlan M; Mahesh, Mahadevappa; McCollough, Cynthia H; Min, James K; Morin, Richard L; Nallamothu, Brahmajee K; Nasir, Khurram; Redberg, Rita F; Shaw, Leslee J

    2014-11-01

    Education, justification, and optimization are the cornerstones to enhancing the radiation safety of medical imaging. Education regarding the benefits and risks of imaging and the principles of radiation safety is required for all clinicians in order for them to be able to use imaging optimally. Empowering patients with knowledge of the benefits and risks of imaging will facilitate their meaningful participation in decisions related to their health care, which is necessary to achieve patient-centered care. Limiting the use of imaging to appropriate clinical indications can ensure that the benefits of imaging outweigh any potential risks. Finally, the continually expanding repertoire of techniques that allow high-quality imaging with lower radiation exposure should be used when available to achieve safer imaging. The implementation of these strategies in practice is necessary to achieve high-quality, patient-centered imaging and will require a shared effort and investment by all stakeholders, including physicians, patients, national scientific and educational organizations, politicians, and industry.

  5. Stakeholder Transportation Scorecard: Reviewing Nevada's Recommendations for Enhancing the Safety and Security of Nuclear Waste Shipments - 13518

    Energy Technology Data Exchange (ETDEWEB)

    Dilger, Fred C. [Black Mountain Research, Henderson, NV 81012 (United States); Ballard, James D. [Department of Sociology, California State University, Northridge, CA 91330 (United States); Halstead, Robert J. [State of Nevada Agency for Nuclear Projects, Carson City, NV 80906 (United States)

    2013-07-01

    As a primary stakeholder in the Yucca Mountain program, the state of Nevada has spent three decades examining and considering national policy regarding spent nuclear fuel and high-level radioactive waste transportation. During this time, Nevada has identified 10 issues it believes are critical to ensuring the safety and security of any spent nuclear fuel transportation program, and achieving public acceptance. These recommendations are: 1) Ship the oldest fuel first; 2) Ship mostly by rail; 3) Use dual-purpose (transportable storage) casks; 4) Use dedicated trains for rail shipments; 5) Implement a full-scale cask testing program; 6) Utilize a National Environmental Policy Act (NEPA) process for the selection of a new rail spur to the proposed repository site; 7) Implement the Western Interstate Energy Board (WIEB) 'straw man' process for route selection; 8) Implement Section 180C assistance to affected States, Tribes and localities through rulemaking; 9) Adopt safety and security regulatory enhancements proposed states; and 10) Address stakeholder concerns about terrorism and sabotage. This paper describes Nevada's proposals in detail and examines their current status. The paper describes the various forums and methods by which Nevada has presented its arguments and sought to influence national policy. As of 2012, most of Nevada's recommendations have been adopted in one form or another, although not yet implemented. If implemented in a future nuclear waste program, the State of Nevada believes these recommendations would form the basis for a successful national transportation plan for shipments to a geologic repository and/or centralized interim storage facility. (authors)

  6. Privacy Enhanced Key Agreement for Public Safety Communication in Wireless Mesh Networks

    Directory of Open Access Journals (Sweden)

    Qian Wei

    2011-08-01

    Full Text Available With the requirements of mobility, flexibility, and rapid response, wireless mesh networks are widely used for emergency services to improve the efficiency of public safety communication to prevent or respond to incidents that harm or endanger persons or property. In this paper, we propose a practical scheme of key agreement with asymmetric encryption based on station-to-station protocol and a privacy enhanced scheme of key agreement with directed signature using the elliptic curve ElGamal cryptography for public safety communication in wireless mesh networks. In the result, only both participants can gain the shared secret key, however, any party else can not understand the key agreement process clearly. We analyze the properties of security and efficiency of the privacy enhanced scheme of key agreement in comparison to the station-to-station protocol and the practical scheme of key agreement with asymmetric encryption. The results of experiment show that the privacy enhanced scheme of key agreement can provide resistance to the unknown key-share attacks, privacy protection for sensitive information included in signature and better efficiency in terms of computational cost.

  7. Magnetic-Field-Assisted Assembly of Anisotropic Superstructures by Iron Oxide Nanoparticles and Their Enhanced Magnetism

    Science.gov (United States)

    Jiang, Chengpeng; Leung, Chi Wah; Pong, Philip W. T.

    2016-04-01

    Magnetic nanoparticle superstructures with controlled magnetic alignment and desired structural anisotropy hold promise for applications in data storage and energy storage. Assembly of monodisperse magnetic nanoparticles under a magnetic field could lead to highly ordered superstructures, providing distinctive magnetic properties. In this work, a low-cost fabrication technique was demonstrated to assemble sub-20-nm iron oxide nanoparticles into crystalline superstructures under an in-plane magnetic field. The gradient of the applied magnetic field contributes to the anisotropic formation of micron-sized superstructures. The magnitude of the applied magnetic field promotes the alignment of magnetic moments of the nanoparticles. The strong dipole-dipole interactions between the neighboring nanoparticles lead to a close-packed pattern as an energetically favorable configuration. Rod-shaped and spindle-shaped superstructures with uniform size and controlled spacing were obtained using spherical and polyhedral nanoparticles, respectively. The arrangement and alignment of the superstructures can be tuned by changing the experimental conditions. The two types of superstructures both show enhancement of coercivity and saturation magnetization along the applied field direction, which is presumably associated with the magnetic anisotropy and magnetic dipole interactions of the constituent nanoparticles and the increased shape anisotropy of the superstructures. Our results show that the magnetic-field-assisted assembly technique could be used for fabricating nanomaterial-based structures with controlled geometric dimensions and enhanced magnetic properties for magnetic and energy storage applications.

  8. New software tools for enhanced precision in robot-assisted laser phonomicrosurgery.

    Science.gov (United States)

    Dagnino, Giulio; Mattos, Leonardo S; Caldwell, Darwin G

    2012-01-01

    This paper describes a new software package created to enhance precision during robot-assisted laser phonomicrosurgery procedures. The new software is composed of three tools for camera calibration, automatic tumor segmentation, and laser tracking. These were designed and developed to improve the outcome of this demanding microsurgical technique, and were tested herein to produce quantitative performance data. The experimental setup was based on the motorized laser micromanipulator created by Istituto Italiano di Tecnologia and the experimental protocols followed are fully described in this paper. The results show the new tools are robust and effective: The camera calibration tool reduced residual errors (RMSE) to 0.009 ± 0.002 mm under 40× microscope magnification; the automatic tumor segmentation tool resulted in deep lesion segmentations comparable to manual segmentations (RMSE= 0.160 ± 0.028 mm under 40× magnification); and the laser tracker tool proved to be reliable even during cutting procedures (RMSE= 0.073 ± 0.023 mm under 40× magnification). These results demonstrate the new software package can provide excellent improvements to the previous microsurgical system, leading to important enhancements in surgical outcome.

  9. Magnetic-Field-Assisted Assembly of Anisotropic Superstructures by Iron Oxide Nanoparticles and Their Enhanced Magnetism.

    Science.gov (United States)

    Jiang, Chengpeng; Leung, Chi Wah; Pong, Philip W T

    2016-12-01

    Magnetic nanoparticle superstructures with controlled magnetic alignment and desired structural anisotropy hold promise for applications in data storage and energy storage. Assembly of monodisperse magnetic nanoparticles under a magnetic field could lead to highly ordered superstructures, providing distinctive magnetic properties. In this work, a low-cost fabrication technique was demonstrated to assemble sub-20-nm iron oxide nanoparticles into crystalline superstructures under an in-plane magnetic field. The gradient of the applied magnetic field contributes to the anisotropic formation of micron-sized superstructures. The magnitude of the applied magnetic field promotes the alignment of magnetic moments of the nanoparticles. The strong dipole-dipole interactions between the neighboring nanoparticles lead to a close-packed pattern as an energetically favorable configuration. Rod-shaped and spindle-shaped superstructures with uniform size and controlled spacing were obtained using spherical and polyhedral nanoparticles, respectively. The arrangement and alignment of the superstructures can be tuned by changing the experimental conditions. The two types of superstructures both show enhancement of coercivity and saturation magnetization along the applied field direction, which is presumably associated with the magnetic anisotropy and magnetic dipole interactions of the constituent nanoparticles and the increased shape anisotropy of the superstructures. Our results show that the magnetic-field-assisted assembly technique could be used for fabricating nanomaterial-based structures with controlled geometric dimensions and enhanced magnetic properties for magnetic and energy storage applications. PMID:27067737

  10. An expert assistant for the treatment of human reliability analysis (HRA) for probabilistic safety analysis (PSA) purposes

    International Nuclear Information System (INIS)

    The value of Probabilistic Safety Analysis (PSA) for nuclear safety is well known and recognized. However, PSA methodology has limitations, particularly when the operator actions are involved in the PSA models. The results of the PSA performed up to now show that human actions are the main contributor to the core damage probability. The HRA intent to provide a framework to identify, analyse, quantify and incorporate the human actions into PSAs. An expert assistant for the treatment of HRA: ETHRA prototype was developed to provide a guide for PSA analysts to perform HRA's with the standards and most widely used methods to determine and quantify human actions for PSA applications and these human actions are then incorporated to fault trees and event trees. ETHRA is a system based on methods, rules and demons that include a question/answer user interface by means of checkboxes, valueboxes and forms. Subject discussed in this report is dealing with the practical implementation and use of ETHRA prototype to PSA applications. (author). 5 refs, 1 fig

  11. Approach to design of future FBRs with enhanced safety and economy

    International Nuclear Information System (INIS)

    After the techno economic demonstration of FBR technology through PFBR, it is essential to achieve high economic competitiveness with enhanced safety on par with other power generation options. Towards this, design studies were made with the objectives of identifying means to achieve enhanced safety, design features for improving economy, conceptualise the plant layout, ways to reduce construction time and to achieve higher capacity factor. This paper describes the outcome of the above studies and the approach to the design of future FBRs with enhanced safety and economy. High economic competitiveness and public acceptance are essential for commercial deployment of fast reactors. India has a well-laid out three phase nuclear power programme with Pressurised Heavy Water Reactors (PHWRs) utilizing natural uranium as fuel in the first phase and fast breeder reactors (FBRs) using plutonium and thorium in the second and third phases. Deploying FBRs on a commercial scale is vital for India in order to utilize the vast thorium reserves and to meet the long term energy needs of the country. As a first step, a 40 MWt, 13.5 MWe Fast Breeder Test Reactor (FBTR) was constructed and has been in operation since 1985. Operation of FBTR has given valuable operating experience with critical systems of FBRs including sodium systems and has given confidence to undertake the design of 500 MWe Prototype Fast Breeder Reactor (PFBR). Construction of PFBR is currently under progress and is expected to be completed by 2010. It is planned to construct four more oxide fuelled FBRs of 500 MWe capacity by 2020 and metal fuelled FBRs of 1000 MWe thereafter. Enhanced safety is proposed to be achieved through improvements in shut down systems, adopting in-vessel primary sodium purification concept, improving the reliability of decay heat removal system, shifting component decontamination activities to a separate building located outside the reactor containment building, providing additional

  12. Operational experience review and methods to enhance safety and reliability in the NPP-Leibstadt (KKL)

    International Nuclear Information System (INIS)

    In the nuclear community it became clear that an integrated feedback system of operating experience must also include the unsuccessful results. The deviations, expected to achieved performance are analysed to the failure mode and its effect. KKL has lowered the number of safety significant events since commercial operation started. The thoroughness of the review/analysis of the events has increased with high priority set to human factor induced events in operation and maintenance. Since the participation of the author in the ASSET-Mission in Smolensk in 1993, KKL introduced the ASSET-Root-Cause method and has supplemented it by the HPES (Human Performance Enhancement System). 4 refs, 6 figs

  13. Enhanced passive safety features against ATWS of fast breeder reactors with capabilities of MA incineration

    Energy Technology Data Exchange (ETDEWEB)

    Ninokata, Hisashi; Sawada, Tetsuo; Sato, Manabu [Tokyo Institute of Technology (Japan)] [and others

    1997-12-01

    The paper gives an outline of the general and simple reactivity correlation method to identify the region of the major design parameters that assures power stabilization and passive shutdown of sodium-cooled large fast reactors under ATWS conditions. Based on the model developed, general design guidelines are shown that enhance passive capabilities being aimed at preventing sodium boiling and fuel failures in the events of ULOF and UTOP. Discussions extend to the influences of minor actinides loading in the core onto the passive safety features. 6 refs., 1 fig., 1 tab.

  14. Robot-Assisted Transaxillary Thyroid Surgery—Feasibility and Safety of a Novel Technique

    Directory of Open Access Journals (Sweden)

    Naomi Rabinovics

    2014-04-01

    Full Text Available Developments in technology have led to a rapid progress in robotic endocrine surgery applications. With the advent of minimally invasive techniques in thyroid surgery, robot-assisted transaxillary thyroid surgery (RATS has emerged as one of the most promising approaches. Its main advantages are improved cosmetic outcome, avoiding cervical incisions, thereby increasing patient satisfaction, and improved visualization, arms articulations, and precision, resulting in fewer surgical complications. The main disadvantages are potential new injuries to the brachial plexus, esophagus, and trachea, longer operative time, and increased cost compared to conventional thyroidectomy. In skilled hands, RATS is a safe alternative to conservative thyroidectomy and should be presented to patients with aesthetic concerns. As with any new emerging technique, careful patient selection is crucial, and further evidence must be sought to confirm its indications over time.

  15. Hemostatic hydrodissection of the neurovascular bundles during robotic assisted laparoscopic radical prostatectomy: safety and efficacy trial

    Science.gov (United States)

    Parekattil, Sijo J.; Dahm, Philipp; Vieweg, Johannes W.

    2009-02-01

    Preservation of continence and potency after Robotic Assisted Laparoscopic Radical Prostatectomy (RALP) are two key outcome measures that patients consider when comparing different treatment options for localized prostate cancer. Ensuring that positive surgical margins are as low as possible provides oncologic control. Various techniques to optimize these outcomes have been employed. This study presents the early outcomes for Hemostatic Hydrodissection of the Neurovascular Bundles during 86 consecutive RALPs. Positive margin rates were 12.5% overall (9% for pT2 and 28.6% for pT3); continence at 6 months was 100%, at 3 months 90% and at 1 month 66%. In patients with no preoperative erectile dysfunction (preoperative SHIM of 25), 79% had return of erections sufficient for intercourse by 6 months. 2 of these patients were able to have intercourse 2 weeks after surgery. These preliminary findings appear promising.

  16. Safety and Feasibility of Laparoscopic Abdominal Surgery in Patients With Mechanical Circulatory Assist Devices.

    Science.gov (United States)

    Ashfaq, Awais; Chapital, Alyssa B; Johnson, Daniel J; Staley, Linda L; Arabia, Francisco A; Harold, Kristi L

    2016-10-01

    Objectives Increasing number of mechanical circulatory assist devices (MCADs) are being placed in heart failure patients. Morbidity from device placement is high and the outcome of patients who require noncardiac surgery after, is unclear. As laparoscopic interventions are associated with decreased morbidity, we examined the impact of such procedures in these patients. Methods A retrospective review was conducted on 302 patients who underwent MCAD placement from 2005 to 2012. All laparoscopic abdominal surgeries were included and impact on postoperative morbidity and mortality studied. Results Ten out of 16 procedures were laparoscopic with 1 conversion to open. Seven patients had a HeartMate II, 2 had Total Artificial Hearts, and 1 had CentriMag. Four patients had devices for ischemic cardiomyopathy and 6 cases were emergent. Surgeries included 6 laparoscopic cholecystectomies, 2 exploratory laparoscopies, 1 laparoscopic colostomy takedown, and 1 laparoscopic ventral hernia repair with mesh. Median age of the patients was 63 years (range, 29-79 years). Median operative time was 123 minutes (range, 30-380 minutes). Five of 10 patients were on preoperative anticoagulation with average intraoperative blood loss of 150 mL (range, 20-700 mL). There were 3 postoperative complications; acute respiratory failure, acute kidney injury and multisystem organ failure resulting in death not related to the surgical procedure. Conclusion The need for noncardiac surgery in post-MCAD patients is increasing due to limited donors and due to more durable and longer support from newer generation assist devices. While surgery should be approached with caution in this high-risk group, laparoscopic surgery appears to be a safe and successful treatment option. PMID:26839214

  17. Enhancement of ecosystem services during endophyte-assisted aided phytostabilization of metal contaminated mine soil.

    Science.gov (United States)

    Burges, Aritz; Epelde, Lur; Benito, Garazi; Artetxe, Unai; Becerril, José M; Garbisu, Carlos

    2016-08-15

    Endophytic plant growth-promoting bacteria (endophytes) were isolated from a variety of (pseudo)metallophytes growing in an abandoned Zn/Pb mine and then characterized according to their plant growth-promoting traits (i.e. ACC deaminase activity, IAA production, siderophore production, phosphate solubilising capacity, metal and salt tolerance and phenotypic characterization). Initially, under growth chamber conditions, an endophyte-assisted aided phytostabilization study was carried out with Festuca rubra plants (native vs. commercial variety) inoculated with a Pseudomonas sp. isolate and cow slurry as organic amendment. The effect of treatments on soil physicochemical and microbial indicators of soil quality, as well as plant physiological parameters and metal concentrations, was assessed. We performed a complementary interpretation of our data through their grouping within a set of ecosystem services. Although the application of cow slurry had the most pronounced effects on soil quality indicators and ecosystem services, the growth of native F. rubra plants reduced soil bioavailability of Cd and Zn by 19 and 22%, respectively, and enhanced several soil microbial parameters. On the other hand, endophyte (Pseudomonas sp.) inoculation improved the physiological status of F. rubra plants by increasing the content of carotenoids, chlorophylls and Fv/Fm by 69, 65 and 37%, respectively, while also increasing the values of several soil microbial parameters. Finally, a consortium of five endophyte isolates was used for an endophyte-assisted aided phytostabilization field experiment, where lower metal concentrations in native excluder plants were found. Nonetheless, the field inoculation of the endophyte consortium had no effect on the biomass of native plants. PMID:27107647

  18. An abnormal situation modeling method to assist operators in safety-critical systems

    International Nuclear Information System (INIS)

    One of the main causes of accidents in safety-critical systems is human error. In order to reduce human errors in the process of handling abnormal situations that are highly complex and mentally taxing activities, operators need to be supported, from a cognitive perspective, in order to reduce their workload, stress, and the consequent error rate. Of the various cognitive activities, a correct understanding of the situation, i.e. situation awareness (SA), is a crucial factor in improving performance and reducing errors. Despite the importance of SA in decision-making in time- and safety-critical situations, the difficulty of SA modeling and assessment means that very few methods have as yet been developed. This study confronts this challenge, and develops an innovative abnormal situation modeling (ASM) method that exploits the capabilities of risk indicators, Bayesian networks and fuzzy logic systems. The risk indicators are used to identify abnormal situations, Bayesian networks are utilized to model them and a fuzzy logic system is developed to assess them. The ASM method can be used in the development of situation assessment decision support systems that underlie the achievement of SA. The performance of the ASM method is tested through a real case study at a chemical plant. - Highlights: • Bayesian networks are applied to represent operators’ mental models when confront with abnormal situations. • A fuzzy logic system is used to resemble operators’ generating assessment results for every abnormal situation. • A virtual plant user interface and a prototype based on proposed method are developed to simulate a real case

  19. FEASIBILITY AND SAFETY OF CONTRAST-ENHANCED ULTRASOUND IN THE DISTAL LIMB OF SIX HORSES.

    Science.gov (United States)

    Seiler, Gabriela S; Campbell, Nigel; Nixon, Britton; Tsuruta, James K; Dayton, Paul A; Jennings, Samuel; Redding, W Rich; Lustgarten, Meghann

    2016-05-01

    Vascular alterations play important roles in many orthopedic diseases such as osteoarthritis, tendonitis, and synovitis in both human and equine athletes. Understanding these alterations could enhance diagnosis, prognosis, and treatment. Contrast-enhanced ultrasound (CEUS) could be a valuable method for evaluation of blood flow and perfusion of these processes in the equine distal limb, however no reports were found describing feasibility or safety of the technique. The goal of this prospective, experimental study was to describe the feasibility and safety of distal limb CEUS in a sample of six horses. For each horse, CEUS of the distal limb was performed after intravenous injections of 5 and 10 ml, as well as intra-arterial injections of 0.5 and 1 ml contrast medium. Vital parameters were monitored and CEUS images were assessed qualitatively and quantitatively for degree of contrast enhancement. None of the horses had clinically significant changes in their vital parameters after contrast medium injection. One horse had a transient increase in respiratory rate, and several horses had mild increases of systolic blood pressure of short duration after intravenous, but not after intra-arterial injections. Intra-arterial injection was possible in all horses and resulted in significantly improved contrast enhancement both quantitatively (P = 0.027) and qualitatively (P = 0.019). Findings from this study indicated that CEUS is a feasible and safe diagnostic test for evaluation of the equine distal limb. Future studies are needed to assess the clinical utility of this test for horses with musculoskeletal diseases. PMID:26765518

  20. Evaluation of Fiber Bundle Rotation for Enhancing Gas Exchange in a Respiratory Assist Catheter

    OpenAIRE

    Eash, Heide J.; Mihelc, Kevin M.; Frankowski, Brain J.; Hattler, Brack G.; Federspiel, William J.

    2007-01-01

    Supplemental oxygenation and carbon dioxide removal through an intravenous respiratory assist catheter can be used as a means of treating patients with acute respiratory failure. We are beginning development efforts toward a new respiratory assist catheter with an insertional size

  1. Fluorescent carbon nanowires made by pyrolysis of DNA nanofibers and plasmon-assisted emission enhancement of their fluorescence.

    Science.gov (United States)

    Nakao, Hidenobu; Tokonami, Shiho; Yamamoto, Yojiro; Shiigi, Hiroshi; Takeda, Yoshihiko

    2014-10-14

    We report on a facile method for preparing fluorescent carbon nanowires (CNWs) with pyrolysis of highly aligned DNA nanofibers as carbon sources. Silver nanoparticle (AgNP)-doped CNWs were also produced using pyrolysis of DNA nanofibers with well-attached AgNPs, indicating emission enhancement assisted by localized plasmon resonances.

  2. Safety Enhancements for PHWRs Based on Macroscopic Losses of the Fukushima Accident

    Directory of Open Access Journals (Sweden)

    Sang Ho Kim

    2015-01-01

    Full Text Available The role of nuclear energy is to supply electric power on a stable basis to meet increasing demands, reduce carbon dioxide emissions, and maintain stable electric power costs while ensuring safety. The Fukushima accident taught us many lessons for creating safer nuclear power plants. Considering the design of systems, the areas of weakness at the Fukushima nuclear power plants can be divided into three categories: plant protection, electricity supply, and cooling of the nuclear fuel. In this paper, focusing on these three areas, the lessons learned are proposed and applied for pressurized heavy water reactors. Firstly, hard protection against external risks ensures the integrity of components and systems such that they can perform their original functions. Secondly, additional emergency power supply systems for electrical redundancy and diversity can improve the response capabilities for an accident by increasing the availability of active components. Thirdly, cooling for removing decay heat can be augmented by adopting diverse safety systems derived from other types of reactors. This study is expected to contribute to the safety enhancement of pressurized heavy water reactors by applying design changes based on the lessons learned from the Fukushima accident.

  3. Enhancing Student Learning of Research Methods through the Use of Undergraduate Teaching Assistants

    Science.gov (United States)

    Crowe, Jessica; Ceresola, Ryan; Silva, Tony

    2014-01-01

    By using a quasi-experimental design, in this study, we test the effect of undergraduate teaching assistants on student learning. Data were collected from 170 students enrolled in four sections of a quantitative research methods course, two sections without undergraduate teaching assistants and two sections with undergraduate teaching assistants,…

  4. Gypsum plasterboards enhanced with phase change materials: A fire safety assessment using experimental and computational techniques

    Directory of Open Access Journals (Sweden)

    Kolaitis Dionysios I.

    2013-11-01

    Full Text Available Phase Change Materials (PCM can be used for thermal energy storage, aiming to enhance building energy efficiency. Recently, gypsum plasterboards with incorporated paraffin-based PCM blends have become commercially available. In the high temperature environment developed during a fire, the paraffins, which exhibit relatively low boiling points, may evaporate and, escaping through the gypsum plasterboard's porous structure, emerge to the fire region, where they may ignite, thus adversely affecting the fire resistance characteristics of the building. Aiming to assess the fire safety behaviour of such building materials, an extensive experimental and computational analysis is performed. The fire behaviour and the main thermo-physical physical properties of PCM-enhanced gypsum plasterboards are investigated, using a variety of standard tests and devices (Scanning Electron Microscopy, Thermo Gravimetric Analysis, Cone Calorimeter. The obtained results are used to develop a dedicated numerical model, which is implemented in a CFD code. CFD simulations are validated using measurements obtained in a cone calorimeter. In addition, the CFD code is used to simulate an ISO 9705 room exposed to fire conditions, demonstrating that PCM addition may indeed adversely affect the fire safety of a gypsum plasterboard clad building.

  5. Application of fire PSA in enhancing NPP safety: a case study with Indian PHWRS

    International Nuclear Information System (INIS)

    . Studies have also been conducted to analyse the uncertainties involved in various stages of fire risk analysis like fire growth time, fire suppression time etc. to estimate their effect on final result. As an example, Table 1 summarises the comparison between the calculated values of Accident Sequence Frequency (ASF) for the four critical areas as obtained by the application of code COMPBRN IIIe (lumped parameter code) and of FDS (field based code). It is concluded that fire PSA as a decision making tool has been used in reducing the risk and further enhancing the safety of Indian NPP in the context of fire. (authors)

  6. Robot-assisted training of the kinesthetic sense: enhancing proprioception after stroke

    Directory of Open Access Journals (Sweden)

    Dalia eDe Santis

    2015-01-01

    Full Text Available Proprioception has a crucial role in promoting or hindering motor learning. In particular, an intact position sense strongly correlates with the chances of recovery after stroke. A great majority of neurological patients present both motor dysfunctions and impairments in kinesthesia, but traditional robot and virtual reality training techniques focus either in recovering motor functions or in assessing proprioceptive deficits. An open challenge is to implement effective and reliable tests and training protocols for proprioception that go beyond the mere position sense evaluation and exploit the intrinsic bidirectionality of the kinesthetic sense, which refers to both sense of position and sense of movement. Modulated haptic interaction has a leading role in promoting sensorimotor integration and it is a natural way to enhance volitional effort. Therefore, we designed a preliminary clinical study to test a new proprioception-based motor training technique for augmenting kinesthetic awareness via haptic feedback. The feedback was provided by a robotic manipulandum and the test involved 7 chronic hemiparetic subjects over three weeks. The protocol included evaluation sessions, that consisted of a psychometric estimate of the subject’s kinesthetic sensation, and training sessions, in which the subject executed planar reaching movements in the absence of vision and under a minimally assistive haptic guidance made by sequences of graded force pulses. The bidirectional haptic interaction between the subject and the robot was optimally adapted to each participant in order to achieve a uniform task difficulty over the workspace. All the subjects consistently improved in the perceptual scores as a consequence of training. Moreover, they could minimize the level of haptic guidance in time. Results suggest that the proposed method is effective in enhancing kinesthetic acuity, but the level of impairment may affect the ability of subjects to retain their

  7. Enhanced boronizing kinetics of alloy steel assisted by surface mechanical attrition treatment

    International Nuclear Information System (INIS)

    Highlights: • Nanostructured surface layer is fabricated on H13 steel assisted by SMAT. • The boronizing kinetics of SMAT sample can be enhanced remarkably. • Borided layer can delay fatigue cracks initiation and impede their propagation. -- Abstract: A nanostructured surface layer was fabricated on AISI H13 steel by means of surface mechanical attrition treatment (SMAT). Boronizing behaviors of the SMAT samples were systematically investigated in comparison with their coarse-grained counterparts. The boron diffusion depth of the SMAT sample with pack boriding treatment at 600 °C for 2 h was about 8 μm, which was much deeper than that of the coarse-grained sample. A much thicker borided layer on the SMAT sample can be synthesized by a duplex boronizing treatment at 600 °C followed by at a higher temperature. The borided layer was composed with monophase of Fe2B and the growth of it exhibited a (0 0 2) preferred orientation. Moreover, the activation energy of boron diffusion for the SMAT sample is 140.3 kJ/mol, which is much lower than 209.4 kJ/mol for the coarse-grained counterpart. The results indicate that the boronizing kinetics can be significantly enhanced in the SMAT sample with a duplex boronizing treatment. Furthermore, the thermal fatigue tests show that the borided layer with excellent oxidation resistance and mechanical strength at elevated temperatures could effectively delay the thermal fatigue cracks initiation and impede their propagation. Therefore, the thermal fatigue property of H13 steel with a duplex boronizing treatment can be improved remarkably

  8. Nanofibril scaffold assisted MEMS artificial hydrogel neuromasts for enhanced sensitivity flow sensing

    Science.gov (United States)

    Kottapalli, Ajay Giri Prakash; Bora, Meghali; Asadnia, Mohsen; Miao, Jianmin; Venkatraman, Subbu S.; Triantafyllou, Michael

    2016-01-01

    We present the development and testing of superficial neuromast-inspired flow sensors that also attain high sensitivity and resolution through a biomimetic hyaulronic acid-based hydrogel cupula dressing. The inspiration comes from the spatially distributed neuromasts of the blind cavefish that live in completely dark undersea caves; the sensors enable the fish to form three-dimensional flow and object maps, enabling them to maneuver efficiently in cluttered environments. A canopy shaped electrospun nanofibril scaffold, inspired by the cupular fibrils, assists the drop-casting process allowing the formation of a prolate spheroid-shaped artificial cupula. Rheological and nanoindentation characterizations showed that the Young’s modulus of the artificial cupula closely matches the biological cupula (10–100 Pa). A comparative experimental study conducted to evaluate the sensitivities of the naked hair cell sensor and the cupula-dressed sensor in sensing steady-state flows demonstrated a sensitivity enhancement by 3.5–5 times due to the presence of hydrogel cupula. The novel strategies of sensor development presented in this report are applicable to the design and fabrication of other biomimetic sensors as well. The developed sensors can be used in the navigation and maneuvering of underwater robots, but can also find applications in biomedical and microfluidic devices.

  9. Security-enhanced phase encryption assisted by nonlinear optical correlation via sparse phase

    Science.gov (United States)

    Chen, Wen; Wang, Xiaogang; Chen, Xudong

    2015-03-01

    We propose a method for security-enhanced phase encryption assisted by a nonlinear optical correlation via a sparse phase. Optical configurations are established based on a phase retrieval algorithm for embedding an input image and the secret data into phase-only masks. We found that when one or a few phase-only masks generated during data hiding are sparse, it is possible to integrate these sparse masks into those phase-only masks generated during the encoding of the input image. Synthesized phase-only masks are used for the recovery, and sparse distributions (i.e., binary maps) for generating the incomplete phase-only masks are considered as additional parameters for the recovery of secret data. It is difficult for unauthorized receivers to know that a useful phase has been sparsely distributed in the finally generated phase-only masks for secret-data recovery. Only when the secret data are correctly verified can the input image obtained with valid keys be claimed as targeted information.

  10. Technical Assistance to Enhance Prevention Capacity: a Research Synthesis of the Evidence Base.

    Science.gov (United States)

    Katz, Jason; Wandersman, Abraham

    2016-05-01

    Despite the availability of many evidence-based prevention interventions (EBIs), gaps exist in bringing these programs into widespread practice. Technical assistance (TA) is a strategy for enhancing the readiness of practitioners to implement EBIs. Although many millions of dollars are spent on TA each year, there is little consensus about what the essential features of TA are and how to provide TA with quality. A broad-based research synthesis methodology was used for analyzing the current evidence base for TA using three frames: (1) applying the Getting To Outcomes (GTO) model for categorizing evidence on TA that specifies tasks for planning, implementing, and evaluating TA; (2) understanding the relevance of a successful relationship between the TA provider and TA recipient; and (3) considering the extent to which TA fits the life cycle needs of the preventive intervention. Results indicated that an explicit model or organizing framework is rarely used to plan, implement, and/or evaluate TA; specific TA tasks performed vary widely across studies; TA is rarely delivered to recipients who are seeking to sustain innovations subsequent to adoption and implementation; however, there is systematic attention to relationships and relationship-building. Overall, this synthesis indicates that the extent to which TA is being delivered systematically is limited. We suggest that funders and other stakeholders develop and implement standards for TA quality in order to ensure that many of these limitations are addressed.

  11. Significantly Enhanced Actuation Performance of IPMC by Surfactant-Assisted Processable MWCNT/Nafion Composite

    Institute of Scientific and Technical Information of China (English)

    Qingsong He; Min Yu; Dingshan Yu; Yan Ding; Zhendong Dai

    2013-01-01

    The performance of Ionic Polymer Metal Composite (IPMC) actuator was significantly enhanced by incorporating surfactant-assisted processable Multi-Walled Carbon Nanotubes (MWCNTs) into a Nation solution.Cationic surfactant Cetyl Trimethyl Ammonium Bromide (CTAB) was employed to disperse MWCNTs in the Nation matrix,forming a homogeneous and stable dispersion of nanotubes.The processing did not involve any strong acid treatment and thus effectively preserved the excellent electronic properties associated with MWCNT.The as-obtained MWCNT/Nafion-IPMC actuator was tested in terms of conductivity,bulk and surface morphology,blocking force and electric current.It was shown that the blocking force and the current of the new IPMC are 2.4 times and 1.67 times higher compared with a pure Nation-based IPMC.Moreover,the MWCNT/IPMC performance is much better than previously reported Nafion-IPMC doped by acid-treated MWCNT.Such significantly improved performance should be attributed to the improvement of electrical property associated with the addition of MWCNTs without acid treatment.

  12. Nanofibril scaffold assisted MEMS artificial hydrogel neuromasts for enhanced sensitivity flow sensing.

    Science.gov (United States)

    Kottapalli, Ajay Giri Prakash; Bora, Meghali; Asadnia, Mohsen; Miao, Jianmin; Venkatraman, Subbu S; Triantafyllou, Michael

    2016-01-14

    We present the development and testing of superficial neuromast-inspired flow sensors that also attain high sensitivity and resolution through a biomimetic hyaulronic acid-based hydrogel cupula dressing. The inspiration comes from the spatially distributed neuromasts of the blind cavefish that live in completely dark undersea caves; the sensors enable the fish to form three-dimensional flow and object maps, enabling them to maneuver efficiently in cluttered environments. A canopy shaped electrospun nanofibril scaffold, inspired by the cupular fibrils, assists the drop-casting process allowing the formation of a prolate spheroid-shaped artificial cupula. Rheological and nanoindentation characterizations showed that the Young's modulus of the artificial cupula closely matches the biological cupula (10-100 Pa). A comparative experimental study conducted to evaluate the sensitivities of the naked hair cell sensor and the cupula-dressed sensor in sensing steady-state flows demonstrated a sensitivity enhancement by 3.5-5 times due to the presence of hydrogel cupula. The novel strategies of sensor development presented in this report are applicable to the design and fabrication of other biomimetic sensors as well. The developed sensors can be used in the navigation and maneuvering of underwater robots, but can also find applications in biomedical and microfluidic devices.

  13. Electrical properties of DLC- (n, p)-Si heterojunctions fabricated by ion-assisted plasma-enhanced deposition and pulsed laser deposition methods

    Science.gov (United States)

    Panosyan, Zhosef R.; Voskanyan, Serjik S.; Yengibaryan, Yerem V.; Avjyan, Karapet E.; Khachatryan, Ashot M.; Matevosyan, Lenrik A.

    2010-10-01

    Electrical characteristics of DLC- (n, p)-Si heterojunctions fabricated by ion-assisted plasma-enhanced deposition and pulsed laser deposition methods were investigated. The mechanisms of carrier flow across the fabricated junctions were analyzed. Keywords: ion-assisted plasma-enhanced deposition, pulsed laser deposition, DLC- (n, p)-Si heterojunctions, currentvoltage & capacitance- voltage characteristics.

  14. Thermal safety of ultrasound-enhanced ocular drug delivery: A modeling study

    International Nuclear Information System (INIS)

    Purpose: Delivery of sufficient amounts of therapeutic drugs into the eye for treatment of various ocular diseases is often a challenging task. Ultrasound was shown to be effective in enhancing ocular drug delivery in the authors’ previous in vitro and in vivo studies. Methods: The study reported here was designed to investigate the safety of ultrasound application and its potential thermal effects in the eye using PZFlex modeling software. The safety limit in this study was set as a temperature increase of no more than 1.5 °C based on regulatory recommendations and previous experimental safety studies. Acoustic and thermal specifications of different human eye tissues were obtained from the published literature. The tissues of particular interest in this modeling safety study were cornea, lens, and the location of optic nerve in the posterior eye. Ultrasound application was modeled at frequencies of 400 kHz–1 MHz, intensities of 0.3–1 W/cm2, and exposure duration of 5 min, which were the parameters used in the authors’ previous drug delivery experiments. The baseline eye temperature was 37 °C. Results: The authors’ results showed that the maximal tissue temperatures after 5 min of ultrasound application were 38, 39, 39.5, and 40 °C in the cornea, 39.5, 40, 42, and 43 °C in the center of the lens, and 37.5, 38.5, and 39 °C in the back of the eye (at the optic nerve location) at frequencies of 400, 600, 800 kHz, and 1 MHz, respectively. Conclusions: The ocular temperatures reached at higher frequencies were considered unsafe based on current recommendations. At a frequency of 400 kHz and intensity of 0.8 W/cm2 (parameters shown in the authors’ previous in vivo studies to be optimal for ocular drug delivery), the temperature increase was small enough to be considered safe inside different ocular tissues. However, the impact of orbital bone and tissue perfusion should be included in future modeling efforts to determine the safety of this

  15. Thermal safety of ultrasound-enhanced ocular drug delivery: A modeling study

    Energy Technology Data Exchange (ETDEWEB)

    Nabili, Marjan, E-mail: mnabili@gwmail.gwu.edu [Department of Electrical and Computer Engineering, The George Washington University, 800 22nd Street NW, Room 5000, Washington, DC 20052 (United States); Geist, Craig, E-mail: cgeist@mfa.gwu.edu, E-mail: zderic@gwu.edu [Department of Ophthalmology, The George Washington University, 2150 Pennsylvania Avenue NW, Floor 2A, Washington, DC 20037 (United States); Zderic, Vesna, E-mail: cgeist@mfa.gwu.edu, E-mail: zderic@gwu.edu [Department of Biomedical Engineering, The George Washington University, 800 22nd Street NW, Room 6670, Washington, DC 20052 (United States)

    2015-10-15

    Purpose: Delivery of sufficient amounts of therapeutic drugs into the eye for treatment of various ocular diseases is often a challenging task. Ultrasound was shown to be effective in enhancing ocular drug delivery in the authors’ previous in vitro and in vivo studies. Methods: The study reported here was designed to investigate the safety of ultrasound application and its potential thermal effects in the eye using PZFlex modeling software. The safety limit in this study was set as a temperature increase of no more than 1.5 °C based on regulatory recommendations and previous experimental safety studies. Acoustic and thermal specifications of different human eye tissues were obtained from the published literature. The tissues of particular interest in this modeling safety study were cornea, lens, and the location of optic nerve in the posterior eye. Ultrasound application was modeled at frequencies of 400 kHz–1 MHz, intensities of 0.3–1 W/cm{sup 2}, and exposure duration of 5 min, which were the parameters used in the authors’ previous drug delivery experiments. The baseline eye temperature was 37 °C. Results: The authors’ results showed that the maximal tissue temperatures after 5 min of ultrasound application were 38, 39, 39.5, and 40 °C in the cornea, 39.5, 40, 42, and 43 °C in the center of the lens, and 37.5, 38.5, and 39 °C in the back of the eye (at the optic nerve location) at frequencies of 400, 600, 800 kHz, and 1 MHz, respectively. Conclusions: The ocular temperatures reached at higher frequencies were considered unsafe based on current recommendations. At a frequency of 400 kHz and intensity of 0.8 W/cm{sup 2} (parameters shown in the authors’ previous in vivo studies to be optimal for ocular drug delivery), the temperature increase was small enough to be considered safe inside different ocular tissues. However, the impact of orbital bone and tissue perfusion should be included in future modeling efforts to determine the safety

  16. Robot-assisted versus other types of radical prostatectomy: population-based safety and cost comparison in Japan, 2012-2013.

    Science.gov (United States)

    Sugihara, Toru; Yasunaga, Hideo; Horiguchi, Hiromasa; Matsui, Hiroki; Fujimura, Tetsuya; Nishimatsu, Hiroaki; Fukuhara, Hiroshi; Kume, Haruki; Changhong, Yu; Kattan, Michael W; Fushimi, Kiyohide; Homma, Yukio

    2014-11-01

    In 2012, Japanese national insurance started covering robot-assisted surgery. We carried out a population-based comparison between robot-assisted and three other types of radical prostatectomy to evaluate the safety of robot-assisted prostatectomy during its initial year. We abstracted data for 7202 open, 2483 laparoscopic, 1181 minimal incision endoscopic, and 2126 robot-assisted radical prostatectomies for oncological stage T3 or less from the Diagnosis Procedure Combination database (April 2012-March 2013). Complication rate, transfusion rate, anesthesia time, postoperative length of stay, and cost were evaluated by pairwise one-to-one propensity-score matching and multivariable analyses with covariants of age, comorbidity, oncological stage, hospital volume, and hospital academic status. The proportion of robot-assisted radical prostatectomies dramatically increased from 8.6% to 24.1% during the first year. Compared with open, laparoscopic, and minimal incision endoscopic surgery, robot-assisted surgery was generally associated with a significantly lower complication rate (odds ratios, 0.25, 0.20, 0.33, respectively), autologous transfusion rate (0.04, 0.31, 0.10), homologous transfusion rate (0.16, 0.48, 0.14), lower cost excluding operation (differences, -5.1%, -1.8% [not significant], -10.8%) and shorter postoperative length of stay (-9.1%, +0.9% [not significant], -18.5%, respectively). However, robot-assisted surgery also resulted in a + 42.6% increase in anesthesia time and +52.4% increase in total cost compared with open surgery (all P robotic surgery led to a dynamic change in prostate cancer surgery. Even in its initial year, robot-assisted radical prostatectomy was carried out with several favorable safety aspects compared to the conventional surgeries despite its having the longest anesthesia time and the highest cost.

  17. An efficient RFID authentication protocol to enhance patient medication safety using elliptic curve cryptography.

    Science.gov (United States)

    Zhang, Zezhong; Qi, Qingqing

    2014-05-01

    Medication errors are very dangerous even fatal since it could cause serious even fatal harm to patients. In order to reduce medication errors, automated patient medication systems using the Radio Frequency Identification (RFID) technology have been used in many hospitals. The data transmitted in those medication systems is very important and sensitive. In the past decade, many security protocols have been proposed to ensure its secure transition attracted wide attention. Due to providing mutual authentication between the medication server and the tag, the RFID authentication protocol is considered as the most important security protocols in those systems. In this paper, we propose a RFID authentication protocol to enhance patient medication safety using elliptic curve cryptography (ECC). The analysis shows the proposed protocol could overcome security weaknesses in previous protocols and has better performance. Therefore, the proposed protocol is very suitable for automated patient medication systems.

  18. The need to optimize inservice testing and inspection to enhance safety

    Energy Technology Data Exchange (ETDEWEB)

    Perry, J.A.

    1996-12-01

    Welcome to the Fourth U.S. Nuclear Regulatory Commission and American Society of Mechanical Engineers (USNRC/ASME) Symposium on Valve and Pump Testing in Nuclear Power Plants. This symposium provides a forum to exchange information on technical and regulatory issues associated with the testing of valves and pumps used in nuclear power plants. Progress made since the last symposium will be discussed along with various methods for in service testing of valves and pumps. Active participation by industry representatives, regulators and consultants will entail discussion of a broad array of ideas and points of view regarding how to improve the in service testing of valves and pumps at nuclear power plants. One of the challenges faced is the need to optimize the in service testing and inspection to enhance safety, operability and reliability. The author addresses this challenge from an ASME Nuclear Codes and Standards point of view.

  19. Control and diagnostics for nuclear power plant performance and safety enhancement

    International Nuclear Information System (INIS)

    As the nuclear industry becomes mature, the emphasis has shifted from design and construction to operations, maintenance, people and management. There is a misconception that in a maturing nuclear industry, technological innovations are no longer important. To the contrary, as the progress of the computer and electronic industries continues its revolutionary pace and as the competitive pressures on the utilities intensifies, technological innovations play an increasingly important role in all aspects of operations of nuclear plants. There are ample opportunities and challenges for making significant contributions by using technology. This paper focuses on the technological advances in the area of diagnostics, control and automation for the enhancement of performance and safety of nuclear plants

  20. A Lithium-Ion Battery with Enhanced Safety Prepared using an Environmentally Friendly Process.

    Science.gov (United States)

    Mueller, Franziska; Loeffler, Nicholas; Kim, Guk-Tae; Diemant, Thomas; Behm, R Jürgen; Passerini, Stefano

    2016-06-01

    A new lithium-ion battery chemistry is presented based on a conversion-alloying anode material, a carbon-coated Fe-doped ZnO (TMO-C), and a LiNi1/3 Mn1/3 Co1/3 O2 (NMC) cathode. Both electrodes were fabricated using an environmentally friendly cellulose-based binding agent. The performance of the new lithium-ion battery was evaluated with a conventional, carbonate-based electrolyte (ethylene carbonate:diethyl carbonate-1 m lithium hexafluorophosphate, EC:DEC 1 m LiPF6 ) and an ionic liquid (IL)-based electrolyte (N-butyl-N-methylpyrrolidinium bis(trifluoromethanesulfonyl)imide-0.2 m lithium bis(trifluoromethanesulfonyl)imide, Pyr14 TFSI 0.2 m LiTFSI), respectively. Galvanostatic charge/discharge tests revealed a reduced rate capability of the TMO-C/Pyr14 TFSI 0.2 m LiTFSI/NMC full-cell compared to the organic electrolyte, but the coulombic efficiency was significantly enhanced. Moreover, the IL-based electrolyte substantially improves the safety of the system due to a higher thermal stability of the formed anodic solid electrolyte interphase and the IL electrolyte itself. While the carbonate-based electrolyte shows sudden degradation reactions, the IL exhibits a slowly increasing heat flow, which does not constitute a serious safety risk.

  1. Criticality safety evaluation for the Advanced Test Reactor enhanced low enriched uranium fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Montierth, Leland M. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-07-19

    The Global Threat Reduction Initiative (GTRI) convert program is developing a high uranium density fuel based on a low enriched uranium (LEU) uranium-molybdenum alloy. Testing of prototypic GTRI fuel elements is necessary to demonstrate integrated fuel performance behavior and scale-up of fabrication techniques. GTRI Enhanced LEU Fuel (ELF) elements based on the ATR-Standard Size elements (all plates fueled) are to be fabricated for testing in the Advanced Test Reactor (ATR). While a specific ELF element design will eventually be provided for detailed analyses and in-core testing, this criticality safety evaluation (CSE) is intended to evaluate a hypothetical ELF element design for criticality safety purposes. Existing criticality analyses have analyzed Standard (HEU) ATR elements from which controls have been derived. This CSE documents analysis that determines the reactivity of the hypothetical ELF fuel elements relative to HEU ATR elements and whether the existing HEU ATR element controls bound the ELF element. The initial calculations presented in this CSE analyzed the original ELF design, now referred to as Mod 0.1. In addition, as part of a fuel meat thickness optimization effort for reactor performance, other designs have been evaluated. As of early 2014 the most current conceptual designs are Mk1A and Mk1B, that were previously referred to as conceptual designs Mod 0.10 and Mod 0.11, respectively. Revision 1 evaluates the reactivity of the ATR HEU Mark IV elements for a comparison with the Mark VII elements.

  2. Criticality safety evaluation for the Advanced Test Reactor enhanced low enriched uranium fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Montierth, Leland M. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-07-19

    The Global Threat Reduction Initiative (GTRI) convert program is developing a high uranium density fuel based on a low enriched uranium (LEU) uranium-molybdenum alloy. Testing of prototypic GTRI fuel elements is necessary to demonstrate integrated fuel performance behavior and scale-up of fabrication techniques. GTRI Enhanced LEU Fuel (ELF) elements based on the ATR-Standard Size elements (all plates fueled) are to be fabricated for testing in the Advanced Test Reactor (ATR). While a specific ELF element design will eventually be provided for detailed analyses and in-core testing, this criticality safety evaluation (CSE) is intended to evaluate a hypothetical ELF element design for criticality safety purposes. Existing criticality analyses have analyzed Standard (HEU) ATR elements from which controls have been derived. This CSE documents analysis that determines the reactivity of the hypothetical ELF fuel elements relative to HEU ATR elements and whether the existing HEU ATR element controls bound the ELF element. The initial calculations presented in this CSE analyzed the original ELF design, now referred to as Mod 0.1. In addition as part of a fuel meat thickness optimization effort for reactor performance other designs have been evaluated. As of early 2014 the most current conceptual designs are Mk1A and Mk1B that were previously referred to as conceptual designs Mod 0.10 and Mod 0.11, respectively. Revision 1 evaluates the reactivity of the ATR HEU Mark IV elements for a comparison with the Mark VII elements.

  3. Pacific Northwest Laboratory annual report for 1983 to the DOE Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness. Part 5. Overview and assessment

    International Nuclear Information System (INIS)

    The 1983 annual report from Pacific Northwest Laboratory (PNL) to the Department of Energy (DOE) describes research in environment, health, and safety conducted during fiscal year 1983. The report again consists of five parts, each in a separate volume. Part 5 of the 1983 Annual Report to the Department of Energy's Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness presents Pacific Northwest Laboratory's progress on work performed for the Office of Nuclear Safety and the Office of Operational Safety. For each project, as identified by the Field Task Proposal/Agreement, articles describe progress made during FY 1983. Authors of these articles represent a broad spectrum of capabilities derived from various segments of the Laboratory, reflecting the interdisciplinary nature of the work

  4. Ultrasound-assisted butyl acetate synthesis catalyzed by Novozym 435: enhanced activity and operational stability.

    Science.gov (United States)

    Martins, Andréa B; Schein, Mirela F; Friedrich, John L R; Fernandez-Lafuente, Roberto; Ayub, Marco A Z; Rodrigues, Rafael C

    2013-09-01

    The influence of low-frequency ultrasound (40 kHz) in the esterification reaction between acetic acid and butanol for flavor ester synthesis catalyzed by the commercial immobilized lipase B from Candida antarctica (Novozym 435) was evaluated. A central composite design and the response surface methodology were used to analyze the effects of the reaction parameters (temperature, substrate molar ratio, enzyme content and added water) and their response (yields of conversion in 2.5 h of reaction). The reaction was carried out using n-hexane as solvent. The optimal conditions for ultrasound-assisted butyl acetate synthesis were found to be: temperature of 46 °C; substrate molar ratio of 3.6:1 butanol:acetic acid; enzyme content of 7%; added water of 0.25%, conditions that are slightly different from those found using mechanical mixing. Over 94% of conversion was obtained in 2.5h under these conditions. The optimal acid concentration for the reaction was determined to be 2.0 M, compared to 0.3 M without ultrasound treatment. Enzyme productivity was significantly improved to around 7.5-fold for each batch when comparing ultrasound and standard mechanical agitation. The biocatalyst could be directly reused for 14 reactions cycles keeping around 70% of its original activity, while activity was virtually zeroed in the third cycle using the standard mixing system. Thus, compared to the traditional mechanical agitation, ultrasound technology not only improves the process productivity, but also enhances enzyme recycling and stability in the presence of acetic acid, being a powerful tool to improve biocatalyst performance in this type of reaction. PMID:23453821

  5. SAFETY

    CERN Multimedia

    C. Schaefer and N. Dupont

    2013-01-01

      “Safety is the highest priority”: this statement from CERN is endorsed by the CMS management. An interpretation of this statement may bring you to the conclusion that you should stop working in order to avoid risks. If the safety is the priority, work is not! This would be a misunderstanding and misinterpretation. One should understand that “working safely” or “operating safely” is the priority at CERN. CERN personnel are exposed to different hazards on many levels on a daily basis. However, risk analyses and assessments are done in order to limit the number and the gravity of accidents. For example, this process takes place each time you cross the road. The hazard is the moving vehicle, the stake is you and the risk might be the risk of collision between both. The same principle has to be applied during our daily work. In particular, keeping in mind the general principles of prevention defined in the late 1980s. These principles wer...

  6. SAFETY

    CERN Multimedia

    M. Plagge, C. Schaefer and N. Dupont

    2013-01-01

    Fire Safety – Essential for a particle detector The CMS detector is a marvel of high technology, one of the most precise particle measurement devices we have built until now. Of course it has to be protected from external and internal incidents like the ones that can occur from fires. Due to the fire load, the permanent availability of oxygen and the presence of various ignition sources mostly based on electricity this has to be addressed. Starting from the beam pipe towards the magnet coil, the detector is protected by flooding it with pure gaseous nitrogen during operation. The outer shell of CMS, namely the yoke and the muon chambers are then covered by an emergency inertion system also based on nitrogen. To ensure maximum fire safety, all materials used comply with the CERN regulations IS 23 and IS 41 with only a few exceptions. Every piece of the 30-tonne polyethylene shielding is high-density material, borated, boxed within steel and coated with intumescent (a paint that creates a thick co...

  7. [Microcystin safety study during Cyanobacteria removal by pressure enhanced coagulation process].

    Science.gov (United States)

    Jiang, Xin-Yue; Luan, Qing; Cong, Hai-Bing; Xu, Si-Tao; Liu, Yu-Jiao; Zhu, Xue-Yuan

    2014-11-01

    Pressure enhanced coagulation and sedimentation technique is an effective way for blue algae treatment. It is not clear whether Cyanobacteria balloon rupture will cause Cyanobacteria cells rupture, resulting in high intracellular concentrations of microcystin LR leak into the water, affecting drinking water safety. Therefore, in this study experimental comparative study of pressure and pre-oxidation of water containing Cyanobacteria was carried out to examine the microcystin LR concentration changes and Cyanobacteria removal efficiency. The results showed that microcystin concentration increase was not significant by the pre-treatment with Cyanobacteria water pressure, while the pre-oxidation process caused a significant increase in the concentration of microcystin. After 0.5-0.8 MPa pressure coagulation and sedimentation, removal of Cyanobacteria basically was over 90%, up to 93.5%, while the removal rate by pre-oxidation was low and unstable. Effluent turbidity is also significantly better in the pre-pressure method than the pre-oxidation. The results indicated that pressure enhanced coagulation is a safe and reliable method for Cyanobacteria removal.

  8. Use of intron-disrupted polyadenylation sites to enhance expression and safety of retroviral vectors.

    Science.gov (United States)

    Ismail, S I; Rohll, J B; Kingsman, S M; Kingsman, A J; Uden, M

    2001-01-01

    Normal mRNA polyadenylation signals are composed of an AAUAAA motif and G/U box spaced 20 to 30 bp apart. If this spacing is increased further, then polyadenylation is disrupted. Previously it has been demonstrated that insertion of an intron will similarly disrupt this signal even though such introns are removed during a nuclear splicing reaction (X. Liu and J. Mertz, Nucleic Acids Res. 21:5256-5263, 1993). This observation has led to the suggestion that polyadenylation site selection is undertaken prior to intron excision. We now present results that both support and extend these observations and in doing so create a novel class of retroviral expression vector with improved qualities. We found that when an intron-disrupted polyadenylation signal is inserted within a retroviral expression vector, such a signal, although reformed in the producer cell, remains benign until transduction, where it is then preferentially used. Thus, we demonstrate that upon transduction these vectors now produce a majority of shortened subgenomic species and as a consequence have a reduced tendency for subsequent mobilization from transduced cells. In addition, we demonstrate that the use of this internal signal leads to enhanced expression from such vectors and that this is achieved without any loss in titer. Therefore, split polyadenylation signals confer enhanced performance and improved safety upon retroviral expression vectors into which they are inserted. Such split signals may prove useful for the future optimization of retroviral vectors in gene therapy. PMID:11119589

  9. Plasmon-assisted photoluminescence enhancement of single-walled carbon nanotubes on metal surfaces

    OpenAIRE

    Sakashita, Takerou; Miyauchi, Yuhei; Matsuda, Kazunari; Kanemitsu, Yoshihiko

    2010-01-01

    We demonstrated photoluminescence (PL) enhancement in single carbon nanotubes using localized surface plasmons. Single nanotube spectroscopy revealed triple the PL intensity enhancement for carbon nanotubes on rough Au surfaces as on fused silica surfaces. The PL enhancement depends on the excitation wavelength and distance between the carbon nanotubes and the Au surface. The degree of PL enhancement is determined by the electric field enhancement from the localized surface plasmon and the en...

  10. Phenotypic and marker-assisted genetic enhancement of parental lines of Rajalaxmi, an elite rice hybrid.

    Directory of Open Access Journals (Sweden)

    Amit Kumar Dash

    2016-07-01

    Full Text Available The cytoplasmic male sterile line system comprising CRMS 32A and its maintainer line CRMS 32B is a popular choice for the development of new hybrids in India as CRMS 32A, having Kalinga 1 cytoplasm (other than WA, is a viable alternative to WA cytoplasm. However, both lines are susceptible to bacterial blight (BB, a major disease on rice. As enhancement of host plant resistance is the most effective and economical strategy to control this disease, four resistance genes (Xa4, xa5, xa13 and Xa21 were transferred from a BB pyramid line of IR64, into the A and B lines using a marker-assisted backcrossing (MAB breeding strategy. During the transfer of genes into CRMS 32B, foreground selection was applied using markers associated with the genes, and plants having resistance alleles of the donor, are selected. Selection for morphological and quality traits was practiced to select plants similar to the recurrent parent. The four gene and three gene pyramid lines exhibited high levels of resistance against the BB pathogen when challenged with eight virulent isolates. Using genome wide based SSR markers for background selection, pyramids having >95% of the recurrent parent genome were identified. With CRMS 32B gene pyramid as donor, the four resistance genes were transferred into the A line through repeated backcrosses and the A line pyramids also exhibited high level of resistance against BB. Through a combination of selection at phenotypic and molecular levels, four bacterial blight resistance genes were successfully introduced into two parental lines (CRMS 32 B and A of Rajalaxmi, an elite popular hybrid. The pyramided B lines did exhibit high levels of resistance against BB. Selection for morphological and quality traits and background selection hastened the recovery of the recurrent parent genome in the recombinants. Through repeated backcrosses, all the four resistance genes were transferred to CRMS 32A and test crosses suggest that the maintenance

  11. Phenotypic and Marker-Assisted Genetic Enhancement of Parental Lines of Rajalaxmi, an Elite Rice Hybrid

    Science.gov (United States)

    Dash, Amit K.; Rao, Ravi N.; Rao, G. J. N.; Verma, Ram L.; Katara, Jawahar L.; Mukherjee, Arup K.; Singh, Onkar N.; Bagchi, Torit B.

    2016-01-01

    The cytoplasmic male sterile line system comprising CRMS 32A and its maintainer line CRMS 32B is a popular choice for the development of new hybrids in India as CRMS 32A, having Kalinga 1 cytoplasm (other than WA), is a viable alternative to WA cytoplasm. However, both lines are susceptible to bacterial blight (BB), a major disease on rice. As enhancement of host plant resistance is the most effective and economical strategy to control this disease, four resistance genes (Xa4, xa5, xa13, and Xa21) were transferred from a BB pyramid line of IR64, into the A and B lines using a marker-assisted backcrossing (MAB) breeding strategy. During the transfer of genes into CRMS 32B, foreground selection was applied using markers associated with the genes, and plants having resistance alleles of the donor, are selected. Selection for morphological and quality traits was practiced to select plants similar to the recurrent parent. The four gene and three gene pyramid lines exhibited high levels of resistance against the BB pathogen when challenged with eight virulent isolates. Using genome wide based SSR markers for background selection, pyramids having >95% of the recurrent parent genome were identified. With CRMS 32B gene pyramid as donor, the four resistance genes were transferred into the A line through repeated backcrosses and the A line pyramids also exhibited high level of resistance against BB. Through a combination of selection at phenotypic and molecular levels, four BB resistance genes were successfully introduced into two parental lines (CRMS 32 B and A) of Rajalaxmi, an elite popular hybrid. The pyramided B lines did exhibit high levels of resistance against BB. Selection for morphological and quality traits and background selection hastened the recovery of the recurrent parent genome in the recombinants. Through repeated backcrosses, all the four resistance genes were transferred to CRMS 32A and test crosses suggest that the maintenance ability of the improved CRMS

  12. Electrostatic application of antimicrobial sprays to sanitize food handling and processing surfaces for enhanced food safety

    Energy Technology Data Exchange (ETDEWEB)

    Lyons, Shawn M; Harrison, Mark A [Food Science and Technology Department, University of Georgia, Athens, GA, 30602-2610 (United States); Law, S Edward, E-mail: edlaw@engr.uga.edu [Biological and Agricultural Engineering Department, Applied Electrostatics Laboratory www.ael.engr.uga.edu, University of Georgia, Athens, GA, 30602-4435 (United States)

    2011-06-23

    Human illnesses and deaths caused by foodborne pathogens (e.g., Salmonella enterica, Listeria monocytogenes, Escherichia coli O157:H7, etc.) are of increasing concern globally in maintaining safe food supplies. At various stages of the food production, processing and supply chain antimicrobial agents are required to sanitize contact surfaces. Additionally, during outbreaks of contagious pathogenic microorganisms (e.g., H1N1 influenza), public health requires timely decontamination of extensive surfaces within public schools, mass transit systems, etc. Prior publications verify effectiveness of air-assisted, induction-charged (AAIC) electrostatic spraying of various chemical and biological agents to protect on-farm production of food crops...typically doubling droplet deposition efficiency with concomitant increases in biological control efficacy. Within a biosafety facility this present work evaluated the AAIC electrostatic-spraying process for application of antimicrobial liquids onto various pathogen-inoculated food processing and handling surfaces as a food safety intervention strategy. Fluoroanalysis of AAIC electrostatic sprays (-7.2 mC/kg charge-to-mass ratio) showed significantly greater (p<0.05) mass of tracer active ingredient (A.I.) deposited onto target surfaces at various orientations as compared both to a similar uncharged spray nozzle (0 mC/kg) and to a conventional hydraulic-atomizing nozzle. Per unit mass of A.I. dispensed toward targets, for example, A.I. mass deposited by AAIC electrostatic sprays onto difficult to coat backsides was 6.1-times greater than for similar uncharged sprays and 29.0-times greater than for conventional hydraulic-nozzle sprays. Even at the 56% reduction in peracetic acid sanitizer A.I. dispensed by AAIC electrostatic spray applications, they achieved equal or greater CFU population reductions of Salmonella on most target orientations and materials as compared to uncharged sprays and conventional full-rate hydraulic

  13. Enhancing VHTR passive safety and economy with thermal radiation based direct reactor auxiliary cooling system

    International Nuclear Information System (INIS)

    effective in removing decay heat. By removing the limit on the decay heat removal capability due to the limited available surface area as in a RVACS, the reactor power density and therefore the reactor power can be significantly increased, without losing the passive heat removal feature. This paper introduces the concept of using DRACS to enhance VHTR passive safety and economics. Three design options with different cooling pipe locations are discussed. Analysis results from a lumped volume based model and CFD simulations are presented. (authors)

  14. Task Group report to the Assistant Secretary for Environment, Safety and Health on oversight of chemical safety at the Department of Energy. Volume 2, Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1992-11-01

    This report presents the results of a preliminary review of chemical safety within the Department of Energy (DOE). The review was conducted by Chemical Safety Oversight Review (CSOR) Teams composed of Office of Environment, Safety and Health (EH) staff members and contractors. The primary objective of the CSOR was to assess, the safety status of DOE chemical operations and identify any significant deficiencies associated with such operations. Significant was defined as any situation posing unacceptable risk, that is, imminent danger or threat to workers, co-located workers, the general public, or the environment, that requires prompt action by EH or the line organizations. A secondary objective of the CSOR was to gather and analyze technical and programmatic information related to chemical safety to be used in conjunction with the longer-range EH Workplace Chemical Accident Risk Review (WCARR) Program. The WCARR Program is part of the ongoing EH oversight of nonnuclear safety at all DOE facilities. `` The program objective is to analyze DOE and industry chemical safety programs and performance and determine the need for additional or improved safety guidance for DOE. During the period June 6, 1992, through July 31, 1992, EH conducted CSORs at five DOE sites. The sites visited were Los Alamos National Laboratory (LANL), Savannah River Site (SRS), the Y-12 Plant (Y-12), Oak Ridge National Laboratory (ORNL), and Lawrence Livermore National Laboratory (LLNL).

  15. The Integrated Safety Management System Verification Enhancement Review of the Plutonium Finishing Plant (PFP)

    International Nuclear Information System (INIS)

    The primary purpose of the verification enhancement review was for the DOE Richland Operations Office (RL) to verify contractor readiness for the independent DOE Integrated Safety Management System Verification (ISMSV) on the Plutonium Finishing Plant (PFP). Secondary objectives included: (1) to reinforce the engagement of management and to gauge management commitment and accountability; (2) to evaluate the ''value added'' benefit of direct public involvement; (3) to evaluate the ''value added'' benefit of direct worker involvement; (4) to evaluate the ''value added'' benefit of the panel-to-panel review approach; and, (5) to evaluate the utility of the review's methodology/adaptability to periodic assessments of ISM status. The review was conducted on December 6-8, 1999, and involved the conduct of two-hour interviews with five separate panels of individuals with various management and operations responsibilities related to PFP. A semi-structured interview process was employed by a team of five ''reviewers'' who directed open-ended questions to the panels which focused on: (1) evidence of management commitment, accountability, and involvement; and, (2) consideration and demonstration of stakeholder (including worker) information and involvement opportunities. The purpose of a panel-to-panel dialogue approach was to better spotlight: (1) areas of mutual reinforcement and alignment that could serve as good examples of the management commitment and accountability aspects of ISMS implementation, and, (2) areas of potential discrepancy that could provide opportunities for improvement. In summary, the Review Team found major strengths to include: (1) the use of multi-disciplinary project work teams to plan and do work; (2) the availability and broad usage of multiple tools to help with planning and integrating work; (3) senior management presence and accessibility; (4) the institutionalization of worker involvement; (5) encouragement of self-reporting and self

  16. The Integrated Safety Management System Verification Enhancement Review of the Plutonium Finishing Plant (PFP)

    Energy Technology Data Exchange (ETDEWEB)

    BRIGGS, C.R.

    2000-02-09

    The primary purpose of the verification enhancement review was for the DOE Richland Operations Office (RL) to verify contractor readiness for the independent DOE Integrated Safety Management System Verification (ISMSV) on the Plutonium Finishing Plant (PFP). Secondary objectives included: (1) to reinforce the engagement of management and to gauge management commitment and accountability; (2) to evaluate the ''value added'' benefit of direct public involvement; (3) to evaluate the ''value added'' benefit of direct worker involvement; (4) to evaluate the ''value added'' benefit of the panel-to-panel review approach; and, (5) to evaluate the utility of the review's methodology/adaptability to periodic assessments of ISM status. The review was conducted on December 6-8, 1999, and involved the conduct of two-hour interviews with five separate panels of individuals with various management and operations responsibilities related to PFP. A semi-structured interview process was employed by a team of five ''reviewers'' who directed open-ended questions to the panels which focused on: (1) evidence of management commitment, accountability, and involvement; and, (2) consideration and demonstration of stakeholder (including worker) information and involvement opportunities. The purpose of a panel-to-panel dialogue approach was to better spotlight: (1) areas of mutual reinforcement and alignment that could serve as good examples of the management commitment and accountability aspects of ISMS implementation, and, (2) areas of potential discrepancy that could provide opportunities for improvement. In summary, the Review Team found major strengths to include: (1) the use of multi-disciplinary project work teams to plan and do work; (2) the availability and broad usage of multiple tools to help with planning and integrating work; (3) senior management presence and accessibility; (4) the

  17. Safe Management of Research Reactor MARIA with Special Emphasis on Safety Culture Enhancement Process

    International Nuclear Information System (INIS)

    This paper is focused on the presentation what is the role of the State, Regulatory Body and Operating Organization in the assurance of research reactor MARIA safety. Also the significance of high level of safety culture for safety assurance and the process of its improvement has been highlighted. The process of development and improvement of safety culture contains the issues described in this paper, which we're considerated as the most important and our efforts are focused on their achievement. (author)

  18. Use of low-dose irradiation to enhance the safety and quality of chilled ready meals

    International Nuclear Information System (INIS)

    The market for 'cook-chill' ready meals has expanded significantly during the past ten years. This specific category of food has been defined as a catering system based on the full cooking of food followed by fast chilling and storage in controlled temperature conditions (0-3 deg. C) and subsequent thorough re-heating before consumption. Such meals cover a wide range of commodities including meat, poultry, fish, vegetables, pasta and desserts and are used at home by consumers and by the catering industry for use, for example, as hospital meals or meals-on-wheels. These products have a relatively short shelf-life with a recommended maximum shelf-life of 5 days at 0-3 deg. C including the day of cooking. In addition, there are other concerns with regard to microbiological quality, reduced sensory quality and decreased nutritive value. It has been suggested that low-dose irradiation could be used to extend the shelf-life of these products while at the same time reducing the risk of food poisoning. Research carried out at QUB and DARD has readily demonstrated that the safety and shelf-life of chilled ready meals consisting of meat (chicken, beef or pork) and certain vegetables (e.g. broccoli, carrots and roast potatoes) can be enhanced by irradiation doses of 2 or 3 kGy without having a detrimental effect on sensory or nutritional quality. To date, investigations have been limited to such traditional meals with no research being carried out on the more popular ready meals such as lasagna, cottage pies, curries, etc. which have a relatively short shelf-life upon purchase. It is therefore the objective of this work program to investigate the effect of low-dose irradiation (1-5 kGy) on the microbiological, sensory and nutritional quality of these meals and to determine if their overall quality can be enhanced

  19. The SHIELD (Safety & Health Improvement: Enhancing Law Enforcement Departments) Study: Mixed Methods Longitudinal Findings.

    Science.gov (United States)

    Kuehl, Kerry S; Elliot, Diane L; MacKinnon, David P; O'Rourke, Holly P; DeFrancesco, Carol; Miočević, Milica; Valente, Matthew; Sleigh, Adriana; Garg, Bharti; McGinnis, Wendy; Kuehl, Hannah

    2016-05-01

    The SHIELD (Safety & Health Improvement: Enhancing Law Enforcement Departments) Study is a worksite wellness team-based intervention among police and sheriff departments assessing the program's effectiveness to reduce occupational risks and unhealthy lifestyle behaviors. The SHIELD program focused on improving diet, physical activity, body weight and sleep, and reducing the effects of unhealthy stress and behaviors, such as tobacco and substance abuse. The SHIELD team-based health promotion program was found to be feasible and effective at 6 months in improving diet, sleep, stress, and overall quality of life of law enforcement department personnel. Both intervention and control groups were followed for 24 months, and we report those durability findings, along with qualitative group interview results that provide insight into the changes of the long-term outcomes. Long-term effects were observed for consumption of fruits and vegetables, and there was some evidence for effects on tobacco and alcohol use. Assessment of dietary habits, physical activity behaviors, weight loss maintenance, and substance use is rare more than 1 year following an intervention, and in general, initial positive changes do not persist in prior research. The SHIELD program was feasible, effective, and durable for improving dietary changes. PMID:27158956

  20. Multivariate qualitative analysis of banned additives in food safety using surface enhanced Raman scattering spectroscopy

    Science.gov (United States)

    He, Shixuan; Xie, Wanyi; Zhang, Wei; Zhang, Liqun; Wang, Yunxia; Liu, Xiaoling; Liu, Yulong; Du, Chunlei

    2015-02-01

    A novel strategy which combines iteratively cubic spline fitting baseline correction method with discriminant partial least squares qualitative analysis is employed to analyze the surface enhanced Raman scattering (SERS) spectroscopy of banned food additives, such as Sudan I dye and Rhodamine B in food, Malachite green residues in aquaculture fish. Multivariate qualitative analysis methods, using the combination of spectra preprocessing iteratively cubic spline fitting (ICSF) baseline correction with principal component analysis (PCA) and discriminant partial least squares (DPLS) classification respectively, are applied to investigate the effectiveness of SERS spectroscopy for predicting the class assignments of unknown banned food additives. PCA cannot be used to predict the class assignments of unknown samples. However, the DPLS classification can discriminate the class assignment of unknown banned additives using the information of differences in relative intensities. The results demonstrate that SERS spectroscopy combined with ICSF baseline correction method and exploratory analysis methodology DPLS classification can be potentially used for distinguishing the banned food additives in field of food safety.

  1. Development of a portable bicycle/pedestrian monitoring system for safety enhancement

    Science.gov (United States)

    Usher, Colin; Daley, W. D. R.

    2015-03-01

    Pedestrians involved in roadway accidents account for nearly 12 percent of all traffic fatalities and 59,000 injuries each year. Most injuries occur when pedestrians attempt to cross roads, and there have been noted differences in accident rates midblock vs. at intersections. Collecting data on pedestrian behavior is a time consuming manual process that is prone to error. This leads to a lack of quality information to guide the proper design of lane markings and traffic signals to enhance pedestrian safety. Researchers at the Georgia Tech Research Institute are developing and testing an automated system that can be rapidly deployed for data collection to support the analysis of pedestrian behavior at intersections and midblock crossings with and without traffic signals. This system will analyze the collected video data to automatically identify and characterize the number of pedestrians and their behavior. It consists of a mobile trailer with four high definition pan-tilt cameras for data collection. The software is custom designed and uses state of the art commercial pedestrian detection algorithms. We will be presenting the system hardware and software design, challenges, and results from the preliminary system testing. Preliminary results indicate the ability to provide representative quantitative data on pedestrian motion data more efficiently than current techniques.

  2. The use of interactive computer vision and robot hand controllers for enhancing manufacturing safety

    Science.gov (United States)

    Marzwell, Neville I.; Jacobus, Charles J.; Peurach, Thomas M.; Mitchell, Brian T.

    1994-01-01

    Current available robotic systems provide limited support for CAD-based model-driven visualization, sensing algorithm development and integration, and automated graphical planning systems. This paper describes ongoing work which provides the functionality necessary to apply advanced robotics to automated manufacturing and assembly operations. An interface has been built which incorporates 6-DOF tactile manipulation, displays for three dimensional graphical models, and automated tracking functions which depend on automated machine vision. A set of tools for single and multiple focal plane sensor image processing and understanding has been demonstrated which utilizes object recognition models. The resulting tool will enable sensing and planning from computationally simple graphical objects. A synergistic interplay between human and operator vision is created from programmable feedback received from the controller. This approach can be used as the basis for implementing enhanced safety in automated robotics manufacturing, assembly, repair and inspection tasks in both ground and space applications. Thus, an interactive capability has been developed to match the modeled environment to the real task environment for safe and predictable task execution.

  3. Safety of an Enhanced Recovery Pathway for Patients Undergoing Open Hepatic Resection.

    Directory of Open Access Journals (Sweden)

    Clancy J Clark

    Full Text Available Enhanced recovery pathways (ERP have not been widely implemented for hepatic surgery. The aim of this study was to evaluate the safety of an ERP for patients undergoing open hepatic resection.A single-surgeon, retrospective observational cohort study was performed comparing the clinical outcomes of patients undergoing open hepatic resection treated before and after implementation of an ERP. Morbidity, mortality, and length of hospital stay (LOS were compared between pre-ERP and ERP groups.126 patients (pre-ERP n = 73, ERP n = 53 were identified for the study. Patient characteristics and operative details were similar between groups. Overall complication rate was similar between pre-ERP and ERP groups (37% vs. 28%, p = 0.343. Before and after pathway implementation, the median LOS was similar, 5 (IQR 4-7 vs. 5 (IQR 4-6 days, p = 0.708. After adjusting for age, type of liver resection, and ASA, the ERP group had no increased risk of major complication (OR 0.38, 95% CI 0.14-1.02, p = 0.055 or LOS greater than 5 days (OR 1.21, 95% CI 0.56-2.62, p = 0.627.Routine use of a multimodal ERP is safe and is not associated with increased postoperative morbidity after open hepatic resection.

  4. 78 FR 64468 - Request for Information: Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food...

    Science.gov (United States)

    2013-10-29

    ... healthful food offerings to SNAP recipients and that engage in fraud. These retailers represent a management...) any food or food product for home consumption except alcoholic beverages, tobacco, and hot foods or... Food and Nutrition Service Request for Information: Supplemental Nutrition Assistance Program...

  5. Enhanced ethanol production by removal of cutin and epicuticular waxes of wheat straw by plasma assisted pretreatment

    DEFF Research Database (Denmark)

    Kádár, Zsófia; Schultz-Jensen, Nadja; Jensen, J. S.;

    2015-01-01

    The removal of cutin and epicuticular waxes of wheat straw by PAP (plasma assisted pretreatment) was investigated. Wax removal was observed by Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) as chemical change on the surface of most intensively pretreated samples as well...... as with Scanning Electron Microscopy (SEM) imaging. Compounds resulting from wax degradation were analyzed in the washing water of PAP wheat straw. The wax removal enhanced enzymatic hydrolysis yield and, consequently, the efficiency of wheat straw conversion into ethanol. In total, PAP increased the conversion...

  6. Mechanism of coercivity enhancement by Ag addition in FePt-C granular films for heat assisted magnetic recording media

    International Nuclear Information System (INIS)

    We investigated the Ag distribution in a FePtAg-C granular film that is under consideration for a heat assisted magnetic recording medium by aberration-corrected scanning transmission electron microscope-energy dispersive X-ray spectroscopy and X-ray absorption fine structure. Ag is rejected from the core of FePt grains during the deposition, forming Ag-enriched shell surrounding L10-ordered FePt grains. Since Ag has no solubility in both Fe and Pt, the rejection of Ag induces atomic diffusions thereby enhancing the kinetics of the L10-order in the FePt grains

  7. Direct Fabrication of Carbon Nanotubes STM Tips by Liquid Catalyst-Assisted Microwave Plasma-Enhanced Chemical Vapor Deposition

    Directory of Open Access Journals (Sweden)

    Fa-Kuei Tung

    2009-01-01

    Full Text Available Direct and facile method to make carbon nanotube (CNT tips for scanning tunneling microscopy (STM is presented. Cobalt (Co particles, as catalysts, are electrochemically deposited on the apex of tungsten (W STM tip for CNT growth. It is found that the quantity of Co particles is well controlled by applied DC voltage, concentration of catalyst solution, and deposition time. Using optimum growth condition, CNTs are successfully synthesized on the tip apex by catalyst-assisted microwave-enhanced chemical vapor deposition (CA-MPECVD. A HOPG surface is clearly observed at an atomic scale using the present CNT-STM tip.

  8. Analysis of Material Handling Safety in Construction Sites and Countermeasures for Effective Enhancement

    OpenAIRE

    Anil Kumar, C. N.; Sakthivel, M.; Elangovan, R. K.; Arularasu, M.

    2015-01-01

    One of many hazardous workplaces includes the construction sites as they involve several dangerous tasks. Many studies have revealed that material handling equipment is a major cause of accidents at these sites. Though safety measures are being followed and monitored continuously, accident rates are still high as either workers are unaware of hazards or the safety regulations are not being strictly followed. This paper analyses the safety management systems at construction sites through means...

  9. Enhancing VHTR Passive Safety and Economy with Thermal Radiation Based Direct Reactor Auxiliary Cooling System

    Energy Technology Data Exchange (ETDEWEB)

    Haihua Zhao; Hongbin Zhang; Ling Zou; Xiaodong Sun

    2012-06-01

    inner graphite reflector blocks. There will be gaps between these cooling pipes and their corresponding surrounding graphite surfaces. Graphite has an excellent heat conduction property. By taking advantage of this feature, we can have a volume-based method to remove decay heat. The scalability can be achieved, if needed, by employing more rows of cooling pipes to accommodate higher decay heat rates. Since heat can easily conduct through the graphite regions between the holes made for the cooling pipes, those cooling pipes located further away from the active core region can still be very effective in removing decay heat. By removing the limit on the decay heat removal capability due to the limited available surface area as in a RVACS, the reactor power and power density can be significantly increased, without losing the passive heat removal feature. This paper will introduce the concept of using DRACS to enhance VHTR passive safety and economics. Three design options will be discussed, depending on the cooling pipe locations. Analysis results from a lumped volume based model and CFD simulations will be presented.

  10. Nanomaterial-Assisted Signal Enhancement of Hybridization for DNA Biosensors: A Review

    Directory of Open Access Journals (Sweden)

    Minqiang Li

    2009-09-01

    Full Text Available Detection of DNA sequences has received broad attention due to its potential applications in a variety of fields. As sensitivity of DNA biosensors is determined by signal variation of hybridization events, the signal enhancement is of great significance for improving the sensitivity in DNA detection, which still remains a great challenge. Nanomaterials, which possess some unique chemical and physical properties caused by nanoscale effects, provide a new opportunity for developing novel nanomaterial-based signal-enhancers for DNA biosensors. In this review, recent progress concerning this field, including some newly-developed signal enhancement approaches using quantum-dots, carbon nanotubes and their composites reported by our group and other researchers are comprehensively summarized. Reports on signal enhancement of DNA biosensors by non-nanomaterials, such as enzymes and polymer reagents, are also reviewed for comparison. Furthermore, the prospects for developing DNA biosensors using nanomaterials as signal-enhancers in future are also indicated.

  11. Workflow Enhancement (WE) Improves Safety in Radiation Oncology: Putting the WE and Team Together

    Energy Technology Data Exchange (ETDEWEB)

    Chao, Samuel T., E-mail: chaos@ccf.org [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Cleveland Clinic, Cleveland, Ohio (United States); Meier, Tim; Hugebeck, Brian; Reddy, Chandana A.; Godley, Andrew; Kolar, Matt [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Suh, John H. [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Cleveland Clinic, Cleveland, Ohio (United States)

    2014-07-15

    Purpose: To review the impact of a workflow enhancement (WE) team in reducing treatment errors that reach patients within radiation oncology. Methods and Materials: It was determined that flaws in our workflow and processes resulted in errors reaching the patient. The process improvement team (PIT) was developed in 2010 to reduce errors and was later modified in 2012 into the current WE team. Workflow issues and solutions were discussed in PIT and WE team meetings. Due to tensions within PIT that resulted in employee dissatisfaction, there was a 6-month hiatus between the end of PIT and initiation of the renamed/redesigned WE team. In addition to the PIT/WE team forms, the department had separate incident forms to document treatment errors reaching the patient. These incident forms are rapidly reviewed and monitored by our departmental and institutional quality and safety groups, reflecting how seriously these forms are treated. The number of these incident forms was compared before and after instituting the WE team. Results: When PIT was disbanded, a number of errors seemed to occur in succession, requiring reinstitution and redesign of this team, rebranded the WE team. Interestingly, the number of incident forms per patient visits did not change when comparing 6 months during the PIT, 6 months during the hiatus, and the first 6 months after instituting the WE team (P=.85). However, 6 to 12 months after instituting the WE team, the number of incident forms per patient visits decreased (P=.028). After the WE team, employee satisfaction and commitment to quality increased as demonstrated by Gallup surveys, suggesting a correlation to the WE team. Conclusions: A team focused on addressing workflow and improving processes can reduce the number of errors reaching the patient. Time is necessary before a reduction in errors reaching patients will be seen.

  12. Workflow Enhancement (WE) Improves Safety in Radiation Oncology: Putting the WE and Team Together

    International Nuclear Information System (INIS)

    Purpose: To review the impact of a workflow enhancement (WE) team in reducing treatment errors that reach patients within radiation oncology. Methods and Materials: It was determined that flaws in our workflow and processes resulted in errors reaching the patient. The process improvement team (PIT) was developed in 2010 to reduce errors and was later modified in 2012 into the current WE team. Workflow issues and solutions were discussed in PIT and WE team meetings. Due to tensions within PIT that resulted in employee dissatisfaction, there was a 6-month hiatus between the end of PIT and initiation of the renamed/redesigned WE team. In addition to the PIT/WE team forms, the department had separate incident forms to document treatment errors reaching the patient. These incident forms are rapidly reviewed and monitored by our departmental and institutional quality and safety groups, reflecting how seriously these forms are treated. The number of these incident forms was compared before and after instituting the WE team. Results: When PIT was disbanded, a number of errors seemed to occur in succession, requiring reinstitution and redesign of this team, rebranded the WE team. Interestingly, the number of incident forms per patient visits did not change when comparing 6 months during the PIT, 6 months during the hiatus, and the first 6 months after instituting the WE team (P=.85). However, 6 to 12 months after instituting the WE team, the number of incident forms per patient visits decreased (P=.028). After the WE team, employee satisfaction and commitment to quality increased as demonstrated by Gallup surveys, suggesting a correlation to the WE team. Conclusions: A team focused on addressing workflow and improving processes can reduce the number of errors reaching the patient. Time is necessary before a reduction in errors reaching patients will be seen

  13. Employee assistance programmes as mechanism for enhancing performance at Emfuleni Local Municipality / Stilalla Paulus Mosia

    OpenAIRE

    Mosia, Stilalla Paulus

    2007-01-01

    The role of local government is to ensure that all citizens have access to the basic services. Thus, the Emfuleni Local Municipality has the Constitutional obligation to provide an effective and efficient people-centered administration that will ensure quality and sustainable service delivery. The Emfuleni Local Municipality (ELM) tends to have a culture of non-performance or low service delivery which is prevalent amongst employees or personnel. Employee Assistance Programme (EAP) is the ...

  14. Ankle voluntary movement enhancement following robotic-assisted locomotor training in spinal cord injury

    OpenAIRE

    Varoqui, Deborah; Niu, Xun; Mirbagheri, Mehdi M

    2014-01-01

    Background In incomplete spinal cord injury (iSCI), sensorimotor impairments result in severe limitations to ambulation. To improve walking capacity, physical therapies using robotic-assisted locomotor devices, such as the Lokomat, have been developed. Following locomotor training, an improvement in gait capabilities—characterized by increases in the over-ground walking speed and endurance—is generally observed in patients. To better understand the mechanisms underlying these improvements, we...

  15. Virtual reality for enhancement of robot-assisted gait training in children with central gait disorders

    OpenAIRE

    Brütsch, K; Koenig, Alexander; Zimmerli, Lukas; Mérillat, S; Riener, Robert; Jäncke, Lutz; van Hedel, Hubertus J A; Meyer-Heim, Andreas

    2011-01-01

    Objective: To examine the effect of various forms of training interventions, with and without virtual reality, on the initia- tion and maintenance of active participation during robot- assisted gait training. Design: Intervention study at the Rehabilitation Centre Af- foltern a. A., University Children’s Hospital, Zurich. Subjects: Ten patients (5 males, mean age 12.47 years, stand- ard deviation 1.84 years) with different neurological gait disorders and 14 healthy children (7 males, mean ...

  16. Observation of pitting due to field enhanced surface absorption during laser assisted cleaning of translucent particulates off metal surfaces

    International Nuclear Information System (INIS)

    Highlights: ► Laser assisted cleaning. ► Field enhanced surface absorption. ► Experimental evidence of surface pitting. - Abstract: The field enhanced surface absorption that occurs as a result of focusing of the incident radiation through transparent/semi-transparent contaminant particulates, in addition to their removal, can also leave its signature on the surface in the form of pitting. This has been experimentally verified in case of removal of CsNO3 particulates off stainless steel surface with sub-nanosecond to nanosecond pulses of 1064 nm, 532 nm, and 355 nm wavelengths for which the particulates are semi-transparent. The threshold fluence for such pit formation has been studied as a function of both wavelength and pulse duration of the coherent radiation and was always found to be much higher than the cleaning threshold. Qualitative explanations have been offered to the observed experimental results.

  17. Enhancement of Electron Transfer in Various Photo-Assisted Oxidation Processes for Nitro-Phenolic Compound Conversion

    Science.gov (United States)

    Khue, Do Ngoc; Lam, Tran Dai; Minh, Do Binh; Loi, Vu Duc; Nam, Nguyen Hoai; Bach, Vu Quang; Van Anh, Nguyen; Van Hoang, Nguyen; Hu'ng, Dao Duy

    2016-08-01

    The present study focuses on photo-assisted advanced oxidation processes (AOPs) with strongly enhanced electron transfer for degradation of nitro-phenolic compounds in aqueous medium. The effectiveness of these processes was estimated based on the pseudo-first order rate constant k determined from high-performance liquid chromatography. The degradation of four different nitro-phenolic compounds was systematically studied using selected AOPs; these four compounds were nitrophenol, dinitrophenol, trinitrophenol and trinitroresorcin. It was observed that the combination of ultraviolet light with hydrogen peroxide H2O2 enhanced and maintained hydroxyl radicals, and therefore increased the conversion yield of organic pollutants. These AOPs provided efficient and green removal of stable organic toxins found in a wide range of industrial wastewater.

  18. A numerical method to enhance the performance of a cam-type electric motor-driven left ventricular assist device.

    Science.gov (United States)

    Huang, Huan; Yang, Ming; Lu, Cunyue; Xu, Liang; Zhuang, Xiaoqi; Meng, Fan

    2013-10-01

    Pulsatile left ventricular assist devices (LVADs) driven by electric motors have been widely accepted as a treatment of heart failure. Performance enhancement with computer assistance for this kind of LVAD has seldom been reported. In this article, a numerical method is proposed to assist the design of a cam-type pump. The method requires an integrated model of an LVAD system, consisting of a motor, a transmission mechanism, and a cardiovascular circulation. Performance indices, that is, outlet pressure, outlet flow, and pump efficiency, were used to select the best cam profile from six candidates. A prototype pump connected to a mock circulatory loop (MCL) was used to calibrate the friction coefficient of the cam groove and preliminarily evaluate modeling accuracy. In vitro experiments show that the mean outlet pressure and flow can be predicted with high accuracy by the model, and gross geometries of the measurements can also be reproduced. Simulation results demonstrate that as the total peripheral resistance (TPR) is fixed at 1.1 mm Hg.s/mL, the two-cycle 2/3-rise profile is the best. Compared with other profiles, the maximum increases of pressure and flow indices are 75 and 76%, respectively, and the maximum efficiency increase is over 51%. For different TPRs (0.5∼1.5 mm Hg.s/mL) and operation intervals (0.1∼0.4 s) in counterpulsation, the conclusion is also acceptable.

  19. Consumers Valuations and choice Processes of Food Safety Enhancement Attributes: An International Study of Beef Consumers

    NARCIS (Netherlands)

    Tonsor, G.T.; Schroeder, T.C.; Pennings, J.M.E.; Mintert, J.

    2007-01-01

    Abstract Food safety concerns have had dramatic impacts on food and livestock markets in recent years. Here we examine consumer preferences for various beef food safety assurances. In particular, we evaluate the extent to which such preferences are heterogeneous within and across country-of-residenc

  20. 78 FR 76391 - Proposed Enhancements to the Motor Carrier Safety Measurement System (SMS) Public Web Site

    Science.gov (United States)

    2013-12-17

    ...: Background On November 5, 2013 (78 FR 66420), FMCSA published a notice in the Federal Register requesting... System (SMS) Public Web Site AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION... Safety Measurement System (SMS) public Web site. On December 6, 2013, Advocates ] for Highway and...

  1. Consumer Valuations of Beef Steak Food Safety Enhancement in Canada, Japan, Mexico, and the United States

    NARCIS (Netherlands)

    Tonsor, G.T.; Schroeder, T.C.; Pennings, J.M.E.; Mintert, J.

    2009-01-01

    Food safety concerns have had dramatic impacts on food and livestock markets in recent years. We examine consumer preferences for beef steak food safety assurances. We evaluate the extent to which preferences are heterogeneous within and across country-of-residence defined groups and examine the dis

  2. The PAVE (peeling-assisted volume-enhancing) lift: A retrospective 6-year clinical analysis of a combined approach for facial rejuvenation.

    Science.gov (United States)

    Kaye, Kai Oliver; Schaller, Hans-Eberhard; Jaminet, Patrick; Gonser, Phillipp

    2016-08-01

    The peeling-assisted volume-enhancing (PAVE) lift is a single-stage approach that combines superficial musculoaponeurotic system (SMAS) plication techniques with fat grafting and different peeling agents. To evaluate the safety of this approach, we analyzed the records of 159 patients who underwent surgery between 2008 and 2014. The percentage of complications observed was not higher than values reported in the literature for each treatment entity: surgical facelift: n=3 haematomas (1.89 %), n=2; temporary apraxia of the mandibular branch (1.26%); fat transfer: minor asymmetry in n = 5 cases (3.14%); peeling: temporary hyperpigmentation in trichloroacetic acid (n = 5; 3.8%) and phenol peels (n = 4; 3.1%), permanent hypopigmentation (n = 6; 5.6%), formation of skin miliae persisting longer than 2 to 3 months (n = 5; 4.6%) and prolonged erythema (n = 3; 0.28%) in phenol peels. The single-stage use of chemical peels, autologous fat transfer, and surgical rhytidectomy was safe. PMID:27320171

  3. A new quality approach to wellsite safety

    International Nuclear Information System (INIS)

    Concern for safety and the environment has always been a top priority at Phillips Petroleum Co. In March 1990, a cross-functional team of professionals was charged to examine current practices as they relate to safety in drilling, completions, and workovers; to identify areas of opportunity for improvement; to present recommendations for enhancement of safety practices at the wellsite; and to propose a plan for implementation of the recommendations. The team, called the drilling quality action team (DQAT) under the newly instituted Total Quality Program, included 28 representatives from the company's six regions, the central Drilling and Production Branch, and other organizational units (Safety, Reservoir Engineering, Geology, etc.). This paper reports that a management consulting firm assisted the DQAT through the quality review process and provided facilitators for the team's meetings. A turnkey drilling-contractor/consultant firm assisted by providing input on industry safety practices and reviewing current wellsite safety performance

  4. Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ

    International Nuclear Information System (INIS)

    Consistent with evidence of a strong correlation between interferon gamma (IFNγ) production and rabies virus (RABV) clearance from the CNS, we recently demonstrated that engineering a pathogenic RABV to express IFNγ highly attenuates the virus. Reasoning that IFNγ expression by RABV vaccines would enhance their safety and efficacy, we reverse-engineered two proven vaccine vectors, GAS and GASGAS, to express murine IFNγ. Mortality and morbidity were monitored during suckling mice infection, immunize/challenge experiments and mixed intracranial infections. We demonstrate that GASγ and GASγGAS are significantly attenuated in suckling mice compared to the GASGAS vaccine. GASγ better protects mice from lethal DRV4 RABV infection in both pre- and post-exposure experiments compared to GASGAS. Finally, GASγGAS reduces post-infection neurological sequelae, compared to control, during mixed intracranial infection with DRV4. These data show IFNγ expression by a vaccine vector can enhance its safety while increasing its efficacy as pre- and post-exposure treatment. - Highlights: • IFNγ expression improves attenuated rabies virus safety and immunogenicity. • IFNγ expression is safer and more immunogenic than doubling glycoprotein expression. • Co-infection with IFNγ-expressing RABV prevents wild-type rabies virus lethality. • Vaccine safety and efficacy is additive for IFNγ and double glycoprotein expression

  5. Pre- and post-exposure safety and efficacy of attenuated rabies virus vaccines are enhanced by their expression of IFNγ

    Energy Technology Data Exchange (ETDEWEB)

    Barkhouse, Darryll A. [Department of Cancer Biology, 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States); Center for Neurovirology 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States); Faber, Milosz [Center for Neurovirology 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States); Department of Microbiology and Immunology 1020 Locust St., Jefferson Alumni Hall, Room 465, Philadelphia, PA 19107 (United States); Hooper, D. Craig, E-mail: douglas.hooper@jefferson.edu [Department of Cancer Biology, 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States); Department of Neurological Surgery, 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States); Center for Neurovirology 1020 Locust St., Jefferson Alumni Hall, Room 454, Philadelphia, PA 19107 (United States)

    2015-01-01

    Consistent with evidence of a strong correlation between interferon gamma (IFNγ) production and rabies virus (RABV) clearance from the CNS, we recently demonstrated that engineering a pathogenic RABV to express IFNγ highly attenuates the virus. Reasoning that IFNγ expression by RABV vaccines would enhance their safety and efficacy, we reverse-engineered two proven vaccine vectors, GAS and GASGAS, to express murine IFNγ. Mortality and morbidity were monitored during suckling mice infection, immunize/challenge experiments and mixed intracranial infections. We demonstrate that GASγ and GASγGAS are significantly attenuated in suckling mice compared to the GASGAS vaccine. GASγ better protects mice from lethal DRV4 RABV infection in both pre- and post-exposure experiments compared to GASGAS. Finally, GASγGAS reduces post-infection neurological sequelae, compared to control, during mixed intracranial infection with DRV4. These data show IFNγ expression by a vaccine vector can enhance its safety while increasing its efficacy as pre- and post-exposure treatment. - Highlights: • IFNγ expression improves attenuated rabies virus safety and immunogenicity. • IFNγ expression is safer and more immunogenic than doubling glycoprotein expression. • Co-infection with IFNγ-expressing RABV prevents wild-type rabies virus lethality. • Vaccine safety and efficacy is additive for IFNγ and double glycoprotein expression.

  6. Pacific Northwest Laboratory annual report for 1988 to the Assistant Secretary for Environment, Safety, and Health: Part 5, Environment, safety, health, and quality assurance

    International Nuclear Information System (INIS)

    This document summarizes the research programs now underway at Battelle's Pacific Northwest Laboratory in the areas of environmental safety, health, and quality assurance. Topics include internal irradiation, emergency plans, dose equivalents, risk assessment, dose equivalents, surveys, neutron dosimetry, and radiation accidents

  7. Pacific Northwest Laboratory annual report for 1988 to the Assistant Secretary for Environment, Safety, and Health: Part 5, Environment, safety, health, and quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    Faust, L.G.; Pennell, W.T.; Selby, J.M.

    1989-02-01

    This document summarizes the research programs now underway at Battelle's Pacific Northwest Laboratory in the areas of environmental safety, health, and quality assurance. Topics include internal irradiation, emergency plans, dose equivalents, risk assessment, dose equivalents, surveys, neutron dosimetry, and radiation accidents. (TEM)

  8. Biomimetic MEMS to assist, enhance, and expand human sensory perceptions: a survey on state-of-the-art developments

    Science.gov (United States)

    Makarczuk, Teresa; Matin, Tina R.; Karman, Salmah B.; Diah, S. Zaleha M.; Davaji, Benyamin; Macqueen, Mark O.; Mueller, Jeanette; Schmid, Ulrich; Gebeshuber, Ille C.

    2011-06-01

    The human senses are of extraordinary value but we cannot change them even if this proves to be a disadvantage in modern times. However, we can assist, enhance and expand these senses via MEMS. Current MEMS cover the range of the human sensory system, and additionally provide data about signals that are too weak for the human sensory system (in terms of signal strength) and signal types that are not covered by the human sensory system. Biomimetics deals with knowledge transfer from biology to technology. In our interdisciplinary approach existing MEMS sensor designs shall be modified and adapted (to keep costs at bay), via biomimetic knowledge transfer of outstanding sensory perception in 'best practice' organisms (e.g. thermoreception, UV sensing, electromagnetic sense). The MEMS shall then be linked to the human body (mainly ex corpore to avoid ethics conflicts), to assist, enhance and expand human sensory perception. This paper gives an overview of senses in humans and animals, respective MEMS sensors that are already on the market and gives a list of possible applications of such devices including sensors that vibrate when a blind person approaches a kerb stone edge and devices that allow divers better orientation under water (echolocation, ultrasound).

  9. Enhanced electrokinetic extraction of heavy metals from soils assisted by ion exchange membranes.

    Science.gov (United States)

    Kim, Won-Seok; Kim, Soon-Oh; Kim, Kyoung-Woong

    2005-02-14

    The potential of electrokinetic remediation technology has been successfully demonstrated for the remediation of heavy metal contaminated fine-grained soils through laboratory scale and field application studies. Various enhancement techniques have been proposed and used in order to further improve the remediation process. However, it has been reported that such enhancement schemes can create other obstacles, such as the introduction of non-target ions into the system and thereby decrease the efficiency of the remediation process. Electrokinetic soil remediation technology enhanced by an ion exchange membrane (IEM), IEM-enhanced EK processing, was experimentally evaluated for the purpose of overcoming these obstacles. In particular, this study focused on observations of a fouling problem and its settlement using an auxiliary solution cell (ASC). In addition, the efficacies of two different types of electrode configurations, rectangular and cylindrical, were investigated. The experimental results indicate that the effectiveness of the technology was increased by an enhancement scheme using an IEM. This may be explained by the prevention of metal precipitation in the region near the cathode originating from hydroxide ions generated by the electrolysis of water in the cathode. The experimental results also imply that placement of the ASC can nullify the fouling problem within the cation exchange membranes used in IEM-enhanced EK processing, and thus improve the overall effectiveness of the process. The experimental results indicate that the cylindrical electrode configuration can be implemented in practical situations to improve the treatability of cathode effluent containing a high level of contaminants after processing. PMID:15721533

  10. Twenty-fifth water reactor safety information meeting: Proceedings. Volume 1: Plenary sessions; Pressure vessel research; BWR strainer blockage and other generic safety issues; Environmentally assisted degradation of LWR components; Update on severe accident code improvements and applications

    International Nuclear Information System (INIS)

    This three-volume report contains papers presented at the conference. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Japan, Norway, and Russia. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. This volume contains the following information: (1) plenary sessions; (2) pressure vessel research; (3) BWR strainer blockage and other generic safety issues; (4) environmentally assisted degradation of LWR components; and (5) update on severe accident code improvements and applications. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database

  11. Au-controlled enhancement of photoluminescence of NiS nanostructures synthesized via a microwave-assisted hydrothermal technique

    Energy Technology Data Exchange (ETDEWEB)

    Linganiso, Ella Cebisa [DST/CSIR Nanotech Innovation Centre, National Centre for Nano-structured Materials, Council for Scientific and Industrial Research, PO Box 395, Pretoria 0001 (South Africa); Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Private Bag 3, Wits, 2050 Johannesburg (South Africa); Mwakikunga, Bonex Wakufwa, E-mail: bmwakikunga@csir.co.za [DST/CSIR Nanotech Innovation Centre, National Centre for Nano-structured Materials, Council for Scientific and Industrial Research, PO Box 395, Pretoria 0001 (South Africa); Department of Physics and Biochemical Sciences, The Polytechnic of the University of Malawi, Private Bag 303, Chichiri, Blantyre 0003 (Malawi); Mhlanga, Sabelo Dalton [Department of Applied Chemistry, University of Johannesburg, PO Box 17011, Doornfontein, 2028 Johannesburg (South Africa); Coville, Neil John [Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Private Bag 3, Wits, 2050 Johannesburg (South Africa); DST/NRF Centre of Excellence in Strong Materials, University of the Witwatersrand, Private Bag 3, Wits, 2050 Johannesburg (South Africa)

    2014-11-15

    Nickel sulphide (NiS) nanostructures decorated with gold (Au) nanoparticles (NPs) were synthesized via a microwave-assisted hydrothermal technique. Binary phase NiS (α and β) crystalline nanostructures, bare, and decorated with Au NPs were obtained and confirmed by X-ray diffraction (XRD) studies. TEM analysis revealed that the NiS nanostructures were of various shapes. A quantum confinement effect was confirmed by the blue shift PL emissions and high optical energy band gap observed for the as-synthesized sample. A threefold light emission enhancement due to Au NP coatings was obtained when Au metal NP decoration concentrations was varied from 1% to 10%. These enhancements were attributed to the surface plasmon resonance (SPR) excitation of the surface decorated metal NPs which results in an increased rate of spontaneous emission. The PL enhancement factor was observed to vary at different NiS emissions as well as with the size of the Au NPs. The effect of metal NP decoration on the PL emission of NiS is to the best of our knowledge, presented for the first time. - Highlights: • Binary phase NiS decorated with gold nanoparticles. • Quantum confinement effect confirmed by PL analysis. • PL enhancement depending more on particle size distribution. • Effect of gold on NiS PL is to the best of our knowledge reported for the first time.

  12. Tailored surface-enhanced Raman nanopillar arrays fabricated by laser-assisted replication for biomolecular detection using organic semiconductor lasers.

    Science.gov (United States)

    Liu, Xin; Lebedkin, Sergei; Besser, Heino; Pfleging, Wilhelm; Prinz, Stephan; Wissmann, Markus; Schwab, Patrick M; Nazarenko, Irina; Guttmann, Markus; Kappes, Manfred M; Lemmer, Uli

    2015-01-27

    Organic semiconductor distributed feedback (DFB) lasers are of interest as external or chip-integrated excitation sources in the visible spectral range for miniaturized Raman-on-chip biomolecular detection systems. However, the inherently limited excitation power of such lasers as well as oftentimes low analyte concentrations requires efficient Raman detection schemes. We present an approach using surface-enhanced Raman scattering (SERS) substrates, which has the potential to significantly improve the sensitivity of on-chip Raman detection systems. Instead of lithographically fabricated Au/Ag-coated periodic nanostructures on Si/SiO2 wafers, which can provide large SERS enhancements but are expensive and time-consuming to fabricate, we use low-cost and large-area SERS substrates made via laser-assisted nanoreplication. These substrates comprise gold-coated cyclic olefin copolymer (COC) nanopillar arrays, which show an estimated SERS enhancement factor of up to ∼ 10(7). The effect of the nanopillar diameter (60-260 nm) and interpillar spacing (10-190 nm) on the local electromagnetic field enhancement is studied by finite-difference-time-domain (FDTD) modeling. The favorable SERS detection capability of this setup is verified by using rhodamine 6G and adenosine as analytes and an organic semiconductor DFB laser with an emission wavelength of 631.4 nm as the external fiber-coupled excitation source.

  13. Magnetic field assisted Fenton reactions for the enhanced degradation of methyl blue

    Institute of Scientific and Technical Information of China (English)

    Xiao Long Hao; Lu Yi Zou; Guang Sheng Zhang; Yi Bo Zhang

    2009-01-01

    Magnetic field was tentatively introduced into Fenton reactions system for the degradation and discoloration of methyl blue as the represent of organic chemical dye, which was a bio-refractory organic pollutant in industry wastewater. It was found that under optimal Fenton reaction conditions, with the assistant of magnetic field in Fenton reactions, the degradation rate of methyl blue, the decomposition rate of H2O2 and the conversion rate of Fe2+ were accelerated, the extent of them would be improved by the increase of magnetic field intensity. Meanwhile, the mineralization of methyl blue (CODcr) was improved by over 10% with magnetic fiold.

  14. 1 Outreach, Education and Domestic Market Enhancement 2 Export Promotion and Assistance

    Energy Technology Data Exchange (ETDEWEB)

    Geothermal Energy Association

    2004-03-15

    Geothermal Energy Association supports the US geothermal industry in its efforts to bring more clean geothermal energy on-line throughout the world. Activities designed to accomplish this goal include: (1) developing and maintaining data bases, web pages, (2) commissioning of special studies and reports, (3) preparing, printing and distributing brochures and newsletters, (4) developing exhibits and displays, and participating in trade shows, (5) designing, producing and disseminating audio-video materials, (6) monitoring and coordinating programs carried out by US DOE and other Federal agencies, (7) holding workshops to facilitate communication between researchers and industry and to encourage their recognition of emerging markets for geothermal technology, (8) attending conferences, making speeches and presentation, and otherwise interacting with environmental and other renewable energy organizations and coalitions, (9) hosting events in Washington, DC and other appropriate locations to educate Federal, State and local representatives, environmental groups, the news media, and other about the status and potential of geothermal energy, (10) conducting member services such as the preparation and distribution of a member newsletter related to operating and maintaining s useful and viable association, and (11) performing similar kinds of activities designed to inform others about geothermal energy. The activities of the export promotion aim to assist industry in accomplishing the goal of successfully penetrating and developing energy in country with existing geothermal resources and a desire to develop them. Activities including in export promotion are: (1)needs analysis and assessment involve monitoring the progress of developing markets and projects overseas and working with US industry to determine what future activities by GEA would be of greatest assistance, (2) outreach includes the preparation and dissemination of brochures and videos for foreign professionals

  15. Completion of the VVER 440/213 NPP Mochovce incorporation enhanced safety features

    International Nuclear Information System (INIS)

    The cooperation between the western countries and the countries of ex-eastern block in the field of nuclear safety is recent and still limited. The main reasons for this situation are limited or non existent capabilities of these countries for financing as well as non acceptable legal conditions concerning the third party nuclear liability in this part of Europe. Nevertheless, Framatome and Siemens associated in the consortium named EUCOM, have signed in April 1996 the contract of about 100 million US dollars with Slovak electricity company (SLOVENSKE ELEKTRARNE-SE) for upgrading the Units 1 and 2 of Mochovce Nuclear Power Plant according to the western safety standards. This is the first important project involving west-european companies in the modernisation of Russian type of pressurized water reactor (VVER 440/213). The consortium will cooperate with other partners involved in the project: Slovak, Czech and Russian. The financing of the project will be provided mainly form Slovak and Czech sources. The safety upgrading will be financed through French and German buyer credits. French company Electricite de France (EDF) will be the consultant for SE. The safety upgrading measures have been elaborated taking into account the recommendation of Vienna International Atomic Energy Agency (IAEA) and the evaluation of the safety realised by RISKAUDIT, the common organization of German and French safety authorities (GSR and IPSN). Hence all guaranties have been taken to fulfil the western safety criteria for Nuclear Power Plant Mochovce. (author)

  16. A Study on Enhancement of Understanding of Radiation and Safety Management

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Dong Han; Park, Ji Young; Lee, Jae Uk; Bae, Jun Woo; Kim, Hee Reyoung [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2014-10-15

    Concerns for radiation exposure have been increased from small and big radiation works or experiments with radiation generator (RG) or radiation isotopes (RI) at institutions using radiation in Korea. Actually, due to radiation exposure occurred on the process of handling RI, etc., The exposure should be maintained as low as reasonably possible. To do this, above all, suitable training and establishment of safety culture have to be preceded. In this respect, an education institution is a place where people learn first about handling radiations in various specialties with purposes including academic research, and the first learned habits and practices acts as the basis for safety management of radiation when they continue to do radiation work after going into the society. Hereford, it is needed to establish the right safety culture on radiation for its safe managing. In the present study, the direction for the right understandings and safety improvement are suggested through the radiation survey on education institutions and preparation of safety guidances for users. The basic guidance at the radiation experiment was prepared for the right understanding of the radiation to prevent radiation accidents from careless handling by workers based on the surveyed results for education institutions. It is expected to be used as fundamentals for improvement for radiation safety management of workers and researchers and, further, safety policy for national nuclear energy and radiations.

  17. A Study on Enhancement of Understanding of Radiation and Safety Management

    International Nuclear Information System (INIS)

    Concerns for radiation exposure have been increased from small and big radiation works or experiments with radiation generator (RG) or radiation isotopes (RI) at institutions using radiation in Korea. Actually, due to radiation exposure occurred on the process of handling RI, etc., The exposure should be maintained as low as reasonably possible. To do this, above all, suitable training and establishment of safety culture have to be preceded. In this respect, an education institution is a place where people learn first about handling radiations in various specialties with purposes including academic research, and the first learned habits and practices acts as the basis for safety management of radiation when they continue to do radiation work after going into the society. Hereford, it is needed to establish the right safety culture on radiation for its safe managing. In the present study, the direction for the right understandings and safety improvement are suggested through the radiation survey on education institutions and preparation of safety guidances for users. The basic guidance at the radiation experiment was prepared for the right understanding of the radiation to prevent radiation accidents from careless handling by workers based on the surveyed results for education institutions. It is expected to be used as fundamentals for improvement for radiation safety management of workers and researchers and, further, safety policy for national nuclear energy and radiations

  18. An Enhanced Backbone-Assisted Reliable Framework for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Amna Ali

    2010-03-01

    Full Text Available An extremely reliable source to sink communication is required for most of the contemporary WSN applications especially pertaining to military, healthcare and disaster-recovery. However, due to their intrinsic energy, bandwidth and computational constraints, Wireless Sensor Networks (WSNs encounter several challenges in reliable source to sink communication. In this paper, we present a novel reliable topology that uses reliable hotlines between sensor gateways to boost the reliability of end-to-end transmissions. This reliable and efficient routing alternative reduces the number of average hops from source to the sink. We prove, with the help of analytical evaluation, that communication using hotlines is considerably more reliable than traditional WSN routing. We use reliability theory to analyze the cost and benefit of adding gateway nodes to a backbone-assisted WSN. However, in hotline assisted routing some scenarios where source and the sink are just a couple of hops away might bring more latency, therefore, we present a Signature Based Routing (SBR scheme. SBR enables the gateways to make intelligent routing decisions, based upon the derived signature, hence providing lesser end-to-end delay between source to the sink communication. Finally, we evaluate our proposed hotline based topology with the help of a simulation tool and show that the proposed topology provides manifold increase in end-to-end reliability.

  19. High Energy Density Solid State Li-ion Battery with Enhanced Safety Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop an all solid state Li-ion battery which is capable of delivering high energy density, combined with high safety over a wide operating...

  20. Strategies for enhancing perioperative safety: promoting joy and meaning in the workforce.

    Science.gov (United States)

    Morath, Julianne; Filipp, Rhonda; Cull, Michael

    2014-10-01

    Workforce safety is a precondition of patient safety, and safety from both physical and psychological harm in the workplace is the foundation for an environment in which joy and meaning can exist. Achieving joy and meaning in the workplace allows health care workers to continuously improve the care they provide. This requires an environment in which disrespectful and harmful behaviors are not tolerated or ignored. Health care leaders have an obligation to create workplace cultures that are characterized by respect, transparency, accountability, learning, and quality care. Evidence suggests, however, that health care settings are rife with disrespectful behavior, poor teamwork, and unsafe working conditions. Solutions for addressing workplace safety problems include defining core values, tasking leaders to act as role models, and committing to becoming a high-reliability organization. PMID:25260671

  1. Characteristic emission enhancement in the atmosphere with Rn trace using metal assisted LIBS

    International Nuclear Information System (INIS)

    Several characteristic emission lines from the metal targets (Cu, Zn and Pb) were investigated in trace presence of radon gas in the atmospheric air, using Q-SW Nd:YAG laser induced plasma inside a control chamber. The emission lines of metal species are noticeably enhanced in (Rn+air), relative to those in the synthetic air alone. Similar spectra were also taken in various sub-atmospheric environments in order to determine the optimum pressure for enhancement. Solid-state nuclear track detectors were also employed to count the tracks due to alpha particles for the activity assessment

  2. Earthworms enhance soil health and may also assist in improving biological insect pest suppression in pecans

    Science.gov (United States)

    Prior research indicated that earthworms may serve as phoretic hosts to entomopathogenic nematodes. Therefore, we hypothesized that biocontrol efficacy of entomopathogenic nematodes could be enhanced in the presence of earthworms based on increased nematode dispersal through the soil. We also hypo...

  3. Enhance efficiency of tetraoctylammonium fluoride applied to ultrasound-assisted oxidative desulfurization (UAOD) process

    Energy Technology Data Exchange (ETDEWEB)

    Wan, Meng-Wei; Yen, Teh-Fu [University of Southern California, Department of Civil and Environmental Engineering, Los Angeles, CA 90089-2531 (United States)

    2007-03-01

    The ultrasound-assisted oxidative desulfurization (UAOD) process has been applied to a number of diesel fuels containing varying amounts of sulfur content. The transition metal complex and quaternary ammonium salts (QAS) phase transfer agents have been applied with aqueous hydrogen peroxide as oxidizing agent. High yield of 3-bromobenzothiophene, and 2-bromobenzothiphene sulfone has been found from phase transfer agents containing tetraoctylammonium bromide. No contaminates such as bromo compound derivates had been isolated when the new fluoride phase transfer agent was used. Selectivity was particularly high for this process as demonstrated by selective ions mass spectrometry. The experiment also demonstrated that the catalyst could be recovered for reuse. Furthermore, the hydrogen peroxide provides a good performance, and the oxidation will proceed as low as 0.25%. (author)

  4. Amino acids assisted hydrothermal synthesis of hierarchically structured ZnO with enhanced photocatalytic activities

    Science.gov (United States)

    Guo, Yanxia; Lin, Siwen; Li, Xuan; Liu, Yuping

    2016-10-01

    Novel hierarchically structured ZnO, including rose-like, dandelion-like and flower-like, have been synthesized through a simple hydrothermal process using different amino acids (glutamine, histidine and glycine) as structure-directing agents and urea as deposition agent, followed by subsequent calcination. Amino acids played a crucial role in the formation of hierarchically structured ZnO, and different amino acids could induce different exquisite shapes and assembly ways, as well as more oxygen defects. The prepared hierarchically structured ZnO exhibited excellent photocatalytic activities for the photodegradation of Rhodamine B, which was associated with their special hierarchical structures, large BET surface area and the existence of more oxygen defects. Amino acid-assisted growth mechanism of hierarchically structured ZnO was also discussed.

  5. Prostate Biopsy Assistance System with Gland Deformation Estimation for Enhanced Precision

    CERN Document Server

    Baumann, Michael; Daanen, Vincent; Troccaz, Jocelyne

    2009-01-01

    Computer-assisted prostate biopsies became a very active research area during the last years. Prostate tracking makes it possi- ble to overcome several drawbacks of the current standard transrectal ultrasound (TRUS) biopsy procedure, namely the insufficient targeting accuracy which may lead to a biopsy distribution of poor quality, the very approximate knowledge about the actual location of the sampled tissues which makes it difficult to implement focal therapy strategies based on biopsy results, and finally the difficulty to precisely reach non-ultrasound (US) targets stemming from different modalities, statistical atlases or previous biopsy series. The prostate tracking systems presented so far are limited to rigid transformation tracking. However, the gland can get considerably deformed during the intervention because of US probe pres- sure and patient movements. We propose to use 3D US combined with image-based elastic registration to estimate these deformations. A fast elastic registration algorithm that...

  6. Sedation-assisted Orthopedic Reduction in Emergency Medicine: The Safety and Success of a One Physician/One Nurse Model

    Directory of Open Access Journals (Sweden)

    Vinson, David R

    2013-02-01

    Full Text Available Introduction: Much of the emergency medical research on sedation-assisted orthopedic reductions has been undertaken with two physicians—one dedicated to the sedation and one to the procedure. Clinical practice in community emergency departments (EDs, however, often involves only one physician, who both performs the procedure and simultaneously oversees the crendentialed registered nurse who administers the sedation medication and monitors the patient. Although the dual-physician model is advocated by some, evidence in support of its superiority is lacking. Methods: In this electronic health records review we describe sedation-assisted closed reductions of major joints and forearm fractures in three suburban community EDs. The type of procedure and sedation medication, need for specialty assistance, success rates, and intervention-requiring adverse events are reported. Results: During the 18-month study period, procedural sedation was performed 457 times on 442 patients undergoing closed reduction for shoulder dislocations (n=111, elbow dislocations (n=29, hip dislocations (n=101, and forearm fractures (n=201. In the vast majority of this cohort (98.4% [435/442], a single emergency physician simultaneously managed both the procedural sedation and the initial orthopedic reduction without the assistance of a second physician. The reduction was successful or satisfactory in 96.6% (425/435; 95% confidence interval [CI], 95.8-98.8% of these cases, with a low incidence of intervention-requiring adverse events (2.8% [12/435]; 95% CI, 1.5-4.8%.Conclusion: Sedation-assisted closed reduction of major joint dislocations and forearm fractures can be performed effectively and safely in the ED using a one physician/one nurse model. A policy that requires a separate physician (or nurse anesthetist to administer medications for all sedation-assisted ED procedures appears unwarranted. Further research is needed to determine which specific clinical scenarios

  7. Gain-assisted U-shaped Au nanostructure for ultrahigh sensitivity single molecule detection by surface-enhanced Raman scattering

    International Nuclear Information System (INIS)

    We report an efficient gain-assisted U-shaped Au nanostructure for ultrahigh sensitivity single-molecule detection by surface-enhanced Raman scattering (SERS). The localized surface plasmon resonance (LSPR) amplification property and SERS characteristics of the proposed nanosystem are numerically analyzed by the finite-element method (FEM). The calculations show that the LSPR strength and the local electric field intensity of the active nanosystem can be greatly amplified when the nanosystem reaches its spaser threshold (k thre). Furthermore, the maximum SERS enhancement factor of the nanosystem is as high as 4.7 × 1017 on the Au surface areas and 5.8 × 1018 in volume, respectively. Moreover, there is a high SERS enhancement factor of 1014−1017 on the entire surface of the active nanosystem, which is sufficient for single-molecule detection. Finally, the plasmon hybridization theory and effective LC circuit are used to qualitatively illustrate the red-shift of the resonance wavelength by increasing the geometric parameter W 2. (paper)

  8. Frequency doubled femtosecond Ti:sapphire laser with an assisted enhancement cavity

    Science.gov (United States)

    Jin-Wei, Zhang; Hai-Nian, Han; Lei, Hou; Long, Zhang; Zi-Jiao, Yu; De-Hua, Li; Zhi-Yi, Wei

    2016-01-01

    We report an enhancement cavity for femtosecond Ti:sapphire laser at the repetition rate of 170 MHz. An enhancement factor of 24 is obtained when the injecting pulses have an average power of 1 W and a pulse duration of 80 fs. By placing a BBO crystal at the focus of the cavity, we obtain a 392-mW intracavity doubled-frequency laser, corresponding to a conversion efficiency of 43%. The output power has a long-term stability with a root mean square (RMS) of 0.036%. Project supported by the National Basic Research Program of China (Grant Nos. 2013CB922401 and 2012CB821304) and the National Natural Science Foundation of China (Grant No. 61378040).

  9. L-Lysine assisted synthesis of β-Ni(OH)2 hierarchical hollow microspheres and their enhanced electrochemical capacitance performance

    International Nuclear Information System (INIS)

    Graphical abstract: β-Ni(OH)2 hierarchical hollow microspheres with partial open gaps which are composed of nanosheets have been synthesized via L-lysine assisted self-assembly process. As the electrode material of a supercapacitor, the as-synthesized products have superior capacitive performance. Highlights: ► β-Ni(OH)2 hierarchical hollow microspheres are synthesized via L-lysine assisted process. ► L-Lysine is used as crystal growth modifier to prepare the as-synthesized products. ► β-Ni(OH)2 hierarchical hollow microspheres are composed of nanosheets. ► The structure improves the contact between the electrode and the electrolyte. ► Results show that the as-synthesized products have good electrochemical property. - Abstract: Hierarchical β-Ni(OH)2 hollow microspheres with partial open gaps have successfully been prepared via a facile hydrothermal process with the assistance of L-lysine. The as-prepared products have been characterized by means of X-ray powder diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and N2 adsorption/desorption, respectively. The results reveal that the sample consists of a large scale of porous microspheres which is composed of nanosheets. A possible growth mechanism is proposed including the initial formation of hierarchical hollow microspheres aggregated from nuclei and the subsequent site-specific oriented growth of nanosheets by self-assembly along a preferred growth direction of [1 0 1] at the growth state. It is found that L-lysine used as a crystal growth modifier plays a key role in the formation of this hierarchical structure. This special structure is also responsible for the obvious enhancement of electrochemical properties, which exhibits a high specific capacitance of 1398.5 F g−1 at a current density of 5 mA cm−2 and excellent cycling stability. This hollow microspheres display great potential as electrode materials for electrochemical capacitors.

  10. Controlling and enhancing THz collective electron dynamics in superlattices by chaos-assisted miniband transport

    OpenAIRE

    Greenaway, M. T.; A. G. Balanov; Schoell, E.; Fromhold, T. M.

    2009-01-01

    We show that a tilted magnetic field transforms the structure and THz dynamics of charge domains in a biased semiconductor superlattice. At critical field values, strong coupling between the Bloch and cyclotron motion of a miniband electron triggers chaotic delocalization of the electron orbits, causing strong resonant enhancement of their drift velocity. This dramatically affects the collective electron behavior by inducing multiple propagating charge domains and GHz-THz current oscillations...

  11. VMCast: A VM-Assisted Stability Enhancing Solution for Tree-Based Overlay Multicast.

    Science.gov (United States)

    Gu, Weidong; Zhang, Xinchang; Gong, Bin; Zhang, Wei; Wang, Lu

    2015-01-01

    Tree-based overlay multicast is an effective group communication method for media streaming applications. However, a group member's departure causes all of its descendants to be disconnected from the multicast tree for some time, which results in poor performance. The above problem is difficult to be addressed because overlay multicast tree is intrinsically instable. In this paper, we proposed a novel stability enhancing solution, VMCast, for tree-based overlay multicast. This solution uses two types of on-demand cloud virtual machines (VMs), i.e., multicast VMs (MVMs) and compensation VMs (CVMs). MVMs are used to disseminate the multicast data, whereas CVMs are used to offer streaming compensation. The used VMs in the same cloud datacenter constitute a VM cluster. Each VM cluster is responsible for a service domain (VMSD), and each group member belongs to a specific VMSD. The data source delivers the multicast data to MVMs through a reliable path, and MVMs further disseminate the data to group members along domain overlay multicast trees. The above approach structurally improves the stability of the overlay multicast tree. We further utilized CVM-based streaming compensation to enhance the stability of the data distribution in the VMSDs. VMCast can be used as an extension to existing tree-based overlay multicast solutions, to provide better services for media streaming applications. We applied VMCast to two application instances (i.e., HMTP and HCcast). The results show that it can obviously enhance the stability of the data distribution.

  12. VMCast: A VM-Assisted Stability Enhancing Solution for Tree-Based Overlay Multicast.

    Directory of Open Access Journals (Sweden)

    Weidong Gu

    Full Text Available Tree-based overlay multicast is an effective group communication method for media streaming applications. However, a group member's departure causes all of its descendants to be disconnected from the multicast tree for some time, which results in poor performance. The above problem is difficult to be addressed because overlay multicast tree is intrinsically instable. In this paper, we proposed a novel stability enhancing solution, VMCast, for tree-based overlay multicast. This solution uses two types of on-demand cloud virtual machines (VMs, i.e., multicast VMs (MVMs and compensation VMs (CVMs. MVMs are used to disseminate the multicast data, whereas CVMs are used to offer streaming compensation. The used VMs in the same cloud datacenter constitute a VM cluster. Each VM cluster is responsible for a service domain (VMSD, and each group member belongs to a specific VMSD. The data source delivers the multicast data to MVMs through a reliable path, and MVMs further disseminate the data to group members along domain overlay multicast trees. The above approach structurally improves the stability of the overlay multicast tree. We further utilized CVM-based streaming compensation to enhance the stability of the data distribution in the VMSDs. VMCast can be used as an extension to existing tree-based overlay multicast solutions, to provide better services for media streaming applications. We applied VMCast to two application instances (i.e., HMTP and HCcast. The results show that it can obviously enhance the stability of the data distribution.

  13. Enhanced power conversion efficiency of dye-sensitized solar cells assisted with phosphor materials

    Science.gov (United States)

    Lee, Yong-Min; Kim, Dong In; Hwang, Ki-Hwan; Nam, Sang Hun; Boo, Jin-Hyo

    2016-07-01

    Theoretically dye-sensitized solar cells (DSSCs) are high efficiency solar cells. However, DSSCs have lower power conversion efficiency (PCE) than silicon based solar cells. In this study, we use scattering layer and phosphor materials, such as ZrO2 and Zn2SiO4:Mn (Green), to enhance the PCE of DSSCs. The scattering layer and phosphor materials were prepared and used as an effective scattering layer on the transparent TiO2 photoelectrode through the doctor blade method. We confirmed that the scattering layer improves the PCE and J sc due to the enhancement of light harvesting by increasing the scattering and absorbance in the visible range. Under sun illumination AM 1.5 conditions, the PCE of the mesoporous TiO2 based DSSCs was 5.18%. The PCE of the DSSCs with ZrO2 scattering layer was 5.61% and Zn2SiO4:Mn as the scattering layer was enhanced to 5.72%. In order to compare the change in optical properties, DSSCs were measured by EQE, reflectance and PCE. At the same time, FE-SEM and XRD were used to confirm the structural changes in each layer. [Figure not available: see fulltext.

  14. Enhancing the thermal conductivity of polymer-assisted deposited Al2O3 film by nitrogen doping

    Institute of Scientific and Technical Information of China (English)

    Huang Jiang; Zhang Yin; Pan Tai-Song; Zeng Bo; Hu Guo-Hua; Lin Yuan

    2012-01-01

    Polymer-assisted deposition technique has been used to deposit Al2O3 and N-doped Al2O3 (AlON) thin films on Si(100) substrates.The chemical compositions,crystallinity,and thermal conductivity of the as-grown films have been characterized by X-ray photoelectron spectroscopy (XPS),X-ray diffraction (XRD),and 3-omega method,respectively.Amorphous and polycrystalline Al2O3 and AlON thin films have been formed at 700 ℃ and 1000 ℃.The thermal conductivity results indicated that the effect of nitrogen doping on the thermal conductivity is determined by the competition of the increase of Al-N bonding and the suppression of crystallinity.A 67% enhancement in thermal conductivity has been achieved for the samples grown at 700 ℃,demonstrating that the nitrogen doping is an effective way to improve the thermal performance of polymer-assisted-deposited Al2O3 thin films at a relatively low growth temperature.

  15. Synthesis of diamond-like carbon films on Si substrates by photoemission-assisted plasma-enhanced chemical vapor deposition

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Meng [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Ogawa, Shuichi, E-mail: ogasyu@tagen.tohoku.ac.jp [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Takabayashi, Susumu; Otsuji, Taiichi [Research Institute of Electrical Communication, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Core Research for Evolutionary Science and Technology, Japan Science and Technology Agency, K' s Gobancho Bldg., 7 Gobancho, Chiyoda-ku, Tokyo 102-0076 (Japan); Takakuwa, Yuji [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan)

    2012-11-15

    Diamond-like carbon (DLC) films grown by photoemission-assisted plasma-enhanced chemical vapor deposition (PA-PECVD) have attracted attention as a gate insulator for graphene-channel field effect transistors (GFETs). In this study, the possibility of using PA-PECVD to grow insulating DLC films for GFETs is explored by focusing on the growth rate and uniformity of DLC films on Si substrates. Initially, the DLC films were formed at a constant rate but the growth rate decreased rapidly when the thickness reached approximately 400 nm. This is because of a decrease in photoelectron emissions from the Si substrates as they are covered by DLC films which absorb UV photons. However, the DLC films formed uniformly at thicknesses less than 16%. This result indicates that PA-PECVD is a promising method for growing DLC films as the gate dielectric layer of GFETs.

  16. Optical absorption enhancement in 40 nm ultrathin film silicon solar cells assisted by photonic and plasmonic modes

    Science.gov (United States)

    Saravanan, S.; Dubey, R. S.

    2016-10-01

    Presently, energy problems and environmental issues have attracted the scientific community for the development of cost-effective and high-performance solar cells. Thin film solar cells are cheaper but weak light absorption in longer wavelength has demanded an efficient light trapping scheme for the better harvesting of solar radiation to a maximum possibility. In this paper, we numerically explore the design efforts of an ultrathin film silicon solar cell, integrated with top dielectric and bottom metal gratings. The proposed design is influenced by the localized surface plasmon modes, surface plasmon polariton and optical resonances which leads to the optimal harvesting of sunlight within 40 nm thick absorbing layer. The optimized design of solar cell shows enhanced light absorption with cell efficiency ∼25% at normal transverse magnetic polarization condition. Our design approach assisted by photonic and plasmonic modes is promising for the realization of new generation, low-cost ultrathin film solar cells.

  17. SDS-assisted hydrothermal synthesis of NiO flake-flower architectures with enhanced gas-sensing properties

    Science.gov (United States)

    Miao, Ruiyang; Zeng, Wen; Gao, Qi

    2016-10-01

    A facile hydrothermal route was developed for the preparation of well-aligned hierarchical flower-like NiO nanostructure with the assistance of SDS that served as a structure-directing agent as well as a capping agent in the process of aggregation and assembly. Notably, the NiO sensors exhibit enhanced gas-sensing performance towards ethanol, which could be explained in association with the ultrathin nanosheets that are close to Debye length (LD) scale and thus get the majority carriers fully depleted due to the ionization of adsorbed oxygen, abundant effective gas diffusion paths as well as high surface-to-volume ratio to promote sufficient contact and reaction between the NiO sample and ethanol molecules, and numerous miniature reaction rooms assembled with nanosheets to make the test gas molecules stay long enough for completed gas-sensing reactions. Besides, a novel growth mechanism with the passage of reaction time was also proposed in detail.

  18. Adapting the distress thermometer for cross-cultural research: a method enhanced by Mexican American undergraduate research assistants.

    Science.gov (United States)

    Wells, Jo Nell; Dietz, Tracy J

    2013-01-01

    Spanish-speaking Mexican Americans (MAs) need representation in cancer research studies to provide an empirical base for developing culturally relevant health care interventions. One factor that limits research with MAs is the lack of Spanish language measurement tools. Bilingual, bicultural student research assistants (RAs), working with faculty researchers and translation consultants, adapted the English version Distress Thermometer and Problem List (DT-PL) tool into the Spanish language. Additionally, RAs assessed tool feasibility with five MA women to determine its usefulness for a later study. The translation process resulted in a distress assessment instrument suitable for use in a low-literacy, Spanish-speaking population. RAs can enhance a process of adapting a measurement tool for use in research. Health care researchers should now pilot the Spanish DT-PL tool to assess its reliability and validity.

  19. The LVIS Jr. microstent to assist coil embolization of wide-neck intracranial aneurysms: clinical study to assess safety and efficacy

    Energy Technology Data Exchange (ETDEWEB)

    Moehlenbruch, M.; Herweh, C.; Behrens, L.; Jestaedt, L.; Bendszus, M.; Pham, M. [University of Heidelberg Medical Center, Department of Neuroradiology, Heidelberg (Germany); Amiri, H.; Ringleb, P.A. [University of Heidelberg Medical Center, Department of Neurology, Heidelberg (Germany)

    2014-05-15

    This study was aimed to assess clinical safety and efficacy of the LVIS Jr. microstent in stent-assisted coil embolization of wide-neck intracranial aneurysms. IRB approved single-center interventional clinical study in 22 patients (10 females, 12 males, mean age 55, age range 33-74 years) for the endovascular treatment of wide-neck aneurysms. After obtaining informed consent, patients were included according to the following criteria: aneurysm fundus-to-neck ratio < 2 or neck diameter > 4 mm, and a parent vessel diameter of ≤3.5 mm. Primary end point for clinical safety was absence of death, absence of major or minor stroke, and absence of transient ischemic attack. Primary end point for treatment efficacy was complete angiographic occlusion according to the Raymond-Roy Occlusion Classification (RROC) immediately after the procedure and at follow-up after 3 and 6 months on magnetic resonance imaging (MRI). In 20/22 (91 %) of patients, the primary end point of safety was reached; in the two remaining patients, transient ischemic attack, but no permanent deficit was observed; in 16/22 (73 %), efficient occlusion (RROC1) was reached, and in 6/22 (27 %), a residual neck remained (RROC2). Single [seven with antegrade, two in crossover configuration, and four with ''first-balloon-then-stent'' (FBTS) technique] or double-stent (eight patients with Y configuration and one patient with X configuration) deployment was technically successful in all cases. Deployment of the LVIS Jr. microstent in various single- or double-stent configurations is safe and effective to assist the treatment of intracranial wide-neck aneurysms. (orig.)

  20. The SHIELD (Safety & Health Improvement: Enhancing Law Enforcement Departments Study: Feasibility and Findings

    Directory of Open Access Journals (Sweden)

    Kerry Stephen Kuehl

    2014-05-01

    Full Text Available This randomized prospective trial aimed to assess the feasibility and efficacy of a team-based worksite health and safety intervention for law enforcement personnel. Four-hundred and eight subjects were enrolled and half were randomized to meet participants met for weekly, peer-led sessions delivered from a scripted team-based health and safety curriculum. Curriculum addressed: exercise, nutrition, stress, sleep, body weight, injury, and other unhealthy lifestyle behaviours such as smoking and heavy alcohol use. Health and safety questionnaires administered before and after the intervention found significant improvements for increased fruit and vegetable consumption, overall healthy eating, increased sleep quantity and sleep quality, and reduced personal stress.

  1. ENHANCING QUALITY AND SAFETY MANAGEMENT IN SHIPPING: TANKER MANAGEMENT AND SELF ASSESSMENT

    Directory of Open Access Journals (Sweden)

    Fatih Turker

    2008-01-01

    Full Text Available Shipping industry is governed by a multitude of statutory regulations that support ship safety and pollution prevention efforts at both national and international level. However the studies and experiences show that without “embedding the safety, quality and maritime environmental protection culture” with in the company, external audits can have a limited effect on the ship’s safety and prevention of pollution. Tanker Management and Self Assessment (TMSA is a guideline to measure and assess tanker operators’ management system developed by Oil Companies International Marine Forum (OCIMF. This study focuses the objective and scope of the TMSA by defining its objectives and benefits while arguing its impacts on the overall performance of tanker operator companies.

  2. Effective Nuclear Regulatory Systems: Further Enhancing the Global Nuclear Safety and Security Regime. Proceedings of an International Conference

    International Nuclear Information System (INIS)

    Over the last three decades, Member States, the IAEA and other international organizations have made efforts to strengthen the safety and security of the use of nuclear and radioactive material through strong national infrastructures and consistent international dialogue. To support these efforts, the IAEA has convened a series of major conferences that have addressed topical issues and strategies critical for consideration by the world's nuclear regulators. More recently, the IAEA organized the first International Conference on Effective Nuclear Regulatory Systems: Facing Safety and Security Challenges, which was held in Moscow, Russian Federation in 2006. The idea of a 'global nuclear safety and security regime' was discussed at this conference. In the meantime, this regime has been established as a cooperative mechanism to share principles, norms, rules and decision making procedures to achieve shared goals in nuclear safety and security while preserving and complementing the sovereignty, authority and ultimate responsibilities of States. To further enhance this regime, it is necessary to seek definite commitments and set forth concrete steps towards greater international cooperation on, inter alia: - Addressing emerging regulatory challenges associated with regulating new and existing nuclear power programmes; - Addressing emerging regulatory challenges associated with regulating radiation applications; - Enhancing the effective independence of national regulators and continuously improving regulatory effectiveness; - Addressing the impact of multinational activities on the national responsibility for safety and security; - Developing initiatives for capacity building, including institutional, organisational arrangements and education and training for sustainable regulatory infrastructure; - Promoting synergies and possible integration between safety and security. To address these issues, and to respond to the request by the senior regulators to have a

  3. US advanced liquid metal reactor design and safety enhancements through teamwork with the NRC

    International Nuclear Information System (INIS)

    This paper presents a cost effective approach to providing electricity needs of the United States in the early 21st century through an integrated Advanced Liquid Metal Reactor System (ALMRS). The concept incorporates innovative design and passive safety features to achieve favourable safety and economics simultaneously. The synergistic components of the ALMRS, under development by the United States (US) Department of Energy (DOE), are described. A key aspect of the programme is continuing interaction with US Nuclear Regulatory Commission (NRC) toward standard design certification. This interaction, and the results to date, are also addressed. (author)

  4. Enhancement of biomass conversion in catalytic fast pyrolysis by microwave-assisted formic acid pretreatment.

    Science.gov (United States)

    Feng, Yu; Li, Guangyu; Li, Xiangyu; Zhu, Ning; Xiao, Bo; Li, Jian; Wang, Yujue

    2016-08-01

    This study investigated microwave-assisted formic acid (MW-FA) pretreatment as a possible way to improve aromatic production from catalytic fast pyrolysis (CFP) of lignocellulosic biomass. Results showed that short duration of MW-FA pretreatment (5-10min) could effectively disrupt the recalcitrant structure of beech wood and selectively remove its hemicellulose and lignin components. This increased the accessibility of cellulose component of biomass to subsequent thermal conversion in CFP. Consequently, the MW-FA pretreated beech wood produced 14.0-28.3% higher yields (26.4-29.8C%) for valuable aromatic products in CFP than the untreated control (23.2C%). In addition, the yields of undesired solid residue (char/coke) decreased from 33.1C% for the untreated control to 28.6-29.8C% for the MW-FA pretreated samples. These results demonstrate that MW-FA pretreatment can provide an effective way to improve the product distribution from CFP of lignocellulose. PMID:27176672

  5. Enhanced degradation of 4-nitrophenol by microwave assisted Fe/EDTA process

    International Nuclear Information System (INIS)

    A microwave assisted zero-valent iron oxidation process was studied in order to investigate the synergetic effects of MW irradiation on Fe/EDTA system (Fe/EDTA/MW) treated 4-nitrophenol (4-NP) from aqueous solution. The results indicated that the thermal effect of microwave improved the removal effect of 4-NP and TOC through raising the temperature of the system, as well as the non-thermal effect generated by the interaction between the microwave and the Fe resulting in an increase in the hydrophobic character of Fe surface. During the degradation of 4-NP in Fe/EDTA/MW system, the optimum value for MW power, Fe, EDTA dosage was 400 W, 2 g and 0.4 mM, respectively. The possible pathway for degrading the 4-NP was proposed based on GC/MS and HPLC analysis of the degradation intermediates. The concentration change course of the main bio-refractory by-products, the aminophenol formed in the degradation of 4-NP suggested a more efficient degradation and mineralization in Fe/EDTA/MW system. Finally, BOD5/CODCr of the solution increased from 0.237 to 0.635 after reaction for 18 min, indicating that the biodegradability of wastewater was greatly improved by Fe/EDTA/MW system and would benefit to further treatment by biochemical methods.

  6. Safety; Avertissement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This annual report of the Senior Inspector for the Nuclear Safety, analyses the nuclear safety at EDF for the year 1999 and proposes twelve subjects of consideration to progress. Five technical documents are also provided and discussed concerning the nuclear power plants maintenance and safety (thermal fatigue, vibration fatigue, assisted control and instrumentation of the N4 bearing, 1300 MW reactors containment and time of life of power plants). (A.L.B.)

  7. Stability enhancement of ozone-assisted laminar premixed Bunsen flames in nitrogen co-flow

    KAUST Repository

    Vu, Tran Manh

    2014-04-01

    Ozone (O3) is known as one of the strongest oxidizers and therefore is widely used in many applications. Typically in the combustion field, a combination of non-thermal plasma and combustion systems have been studied focusing on the effects of ozone on flame propagation speeds and ignition characteristics. Here, we experimentally investigated the effects of ozone on blowoff of premixed methane/air and propane/air flames over a full range of equivalence ratios at room temperature and atmospheric pressure by using a co-flow burner and a dielectric barrier discharge. The results with ozone showed that a nozzle exit jet velocity at the moment of flame blowoff (blowoff velocity) significantly increased, and flammability limits for both fuel-lean and rich mixtures were also extended. Ozone had stronger effects of percent enhancement in the blowoff velocity for off-stoichiometric mixtures, while minimum enhancements could be observed around stoichiometric conditions for both fuels showing linear positive dependence on a tested range of ozone concentration up to 3810ppm. Through chemical kinetic simulations, the experimentally observed trends of the enhancement in blowoff velocity were identified as a result of the modification of the laminar burning velocity. Two ozone decomposition pathways of O3+N2→O+O2+N2 and O3+H→O2+OH were identified as the most controlling steps. These reactions, coupled with fuel consumption characteristics of each fuel determined the degree of promotion in laminar burning velocities, supporting experimental observations on blowoff velocities with ozone addition. © 2013 The Combustion Institute.

  8. CTAB-assisted synthesis of S@rGO composite with enhanced photocatalytic activity and photostability

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Changyuan, E-mail: hcy6257@163.com [Jiangxi Key Laboratory of Surface Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China); School of Materials and Mechanical & Electrical Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China); Zheng, Shizheng; Lian, Chengjiang; Hu, Quanhong; Duo, Shuwang [Jiangxi Key Laboratory of Surface Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China); School of Materials and Mechanical & Electrical Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China); Zhang, Rongbin [College of Chemistry, Nanchang University, Nanchang 330013 (China); Chen, Fei [Jiangxi Key Laboratory of Surface Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China); School of Materials and Mechanical & Electrical Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013 (China)

    2015-04-30

    Graphical abstract: - Highlights: • S@rGO composite was prepared by a facile electrostatic attraction in the presence of CTAB. • In the composite, rGO served as an excellent electron transporter to separate charge carriers. • rGO also worked as a protective shell that inhibits the inner sulfur cores from being oxidized. • S@rGO composite showed enhanced photocatalytic activity and photostability for MB degradation. - Abstract: S@rGO(reduced graphene oxide) composites were synthesized by a facile electrostatic attraction in the presence of cetyltriethylammnonium bromide (CTAB). Scanning electron microscopy images show that sulfur particles were wrapped by a thin layer of rGO. The rGO nanocoating enhanced the absorption of visible light, facilitated the separation of photogenerated charges, promoted the adsorption of dye moleculars, and provided the perfect chemical protection to inner sulfur particles. As a result, the rGO nanocoating improved the photocatalytic activity and photostability of the sulfur photocatalyst for the degradation of methylene blue under simulated solar light irradiation. Our results might open up a promising way to develop stable and highly efficient sulfur-based photocatalyst.

  9. CTAB-assisted synthesis of S@rGO composite with enhanced photocatalytic activity and photostability

    International Nuclear Information System (INIS)

    Graphical abstract: - Highlights: • S@rGO composite was prepared by a facile electrostatic attraction in the presence of CTAB. • In the composite, rGO served as an excellent electron transporter to separate charge carriers. • rGO also worked as a protective shell that inhibits the inner sulfur cores from being oxidized. • S@rGO composite showed enhanced photocatalytic activity and photostability for MB degradation. - Abstract: S@rGO(reduced graphene oxide) composites were synthesized by a facile electrostatic attraction in the presence of cetyltriethylammnonium bromide (CTAB). Scanning electron microscopy images show that sulfur particles were wrapped by a thin layer of rGO. The rGO nanocoating enhanced the absorption of visible light, facilitated the separation of photogenerated charges, promoted the adsorption of dye moleculars, and provided the perfect chemical protection to inner sulfur particles. As a result, the rGO nanocoating improved the photocatalytic activity and photostability of the sulfur photocatalyst for the degradation of methylene blue under simulated solar light irradiation. Our results might open up a promising way to develop stable and highly efficient sulfur-based photocatalyst

  10. Enhancing the biocompatibility of microfluidics-assisted fabrication of cell-laden microgels with channel geometry.

    Science.gov (United States)

    Kim, Suntae; Oh, Jonghyun; Cha, Chaenyung

    2016-11-01

    Microfluidic flow-focusing devices (FFD) are widely used to generate monodisperse droplets and microgels with controllable size, shape and composition for various biomedical applications. However, highly inconsistent and often low viability of cells encapsulated within the microgels prepared via microfluidic FFD has been a major concern, and yet this aspect has not been systematically explored. In this study, we demonstrate that the biocompatibility of microfluidic FFD to fabricate cell-laden microgels can be significantly enhanced by controlling the channel geometry. When a single emulsion ("single") microfluidic FFD is used to fabricate cell-laden microgels, there is a significant decrease and batch-to-batch variability in the cell viability, regardless of their size and composition. It is determined that during droplet generation, some of the cells are exposed to the oil phase which is shown to have a cytotoxic effect. Therefore, a microfluidic device with a sequential ('double') flow-focusing channels is employed instead, in which a secondary aqueous phase containing cells enters the primary aqueous phase, so the cells' exposure to the oil phase is minimized by directing them to the center of droplets. This microfluidic channel geometry significantly enhances the biocompatibility of cell-laden microgels, while maintaining the benefits of a typical microfluidic process. This study therefore provides a simple and yet highly effective strategy to improve the biocompatibility of microfluidic fabrication of cell-laden microgels.

  11. Enhancing Nursing Staffing Forecasting With Safety Stock Over Lead Time Modeling.

    Science.gov (United States)

    McNair, Douglas S

    2015-01-01

    In balancing competing priorities, it is essential that nursing staffing provide enough nurses to safely and effectively care for the patients. Mathematical models to predict optimal "safety stocks" have been routine in supply chain management for many years but have up to now not been applied in nursing workforce management. There are various aspects that exhibit similarities between the 2 disciplines, such as an evolving demand forecast according to acuity and the fact that provisioning "stock" to meet demand in a future period has nonzero variable lead time. Under assumptions about the forecasts (eg, the demand process is well fit as an autoregressive process) and about the labor supply process (≥1 shifts' lead time), we show that safety stock over lead time for such systems is effectively equivalent to the corresponding well-studied problem for systems with stationary demand bounds and base stock policies. Hence, we can apply existing models from supply chain analytics to find the optimal safety levels of nurse staffing. We use a case study with real data to demonstrate that there are significant benefits from the inclusion of the forecast process when determining the optimal safety stocks.

  12. Enhanced FAA-Hybrid III dummy for aircraft occupant safety assessment

    NARCIS (Netherlands)

    Waagmeester, C.D.; Ratingen, M.R. van; Giavotto, V.; Notarnicola, L.; Goldner, S.

    2002-01-01

    Following an integral approach unique in aircraft safety, the European HeliSafe project aims to improve the survivability of helicopter crashes and to reduce the risk at injuries for occupants in cockpit and cabin. In the project, a modified FAA-Hybrid III is used for the baseline-, design- and conc

  13. Enhancing Nursing Staffing Forecasting With Safety Stock Over Lead Time Modeling.

    Science.gov (United States)

    McNair, Douglas S

    2015-01-01

    In balancing competing priorities, it is essential that nursing staffing provide enough nurses to safely and effectively care for the patients. Mathematical models to predict optimal "safety stocks" have been routine in supply chain management for many years but have up to now not been applied in nursing workforce management. There are various aspects that exhibit similarities between the 2 disciplines, such as an evolving demand forecast according to acuity and the fact that provisioning "stock" to meet demand in a future period has nonzero variable lead time. Under assumptions about the forecasts (eg, the demand process is well fit as an autoregressive process) and about the labor supply process (≥1 shifts' lead time), we show that safety stock over lead time for such systems is effectively equivalent to the corresponding well-studied problem for systems with stationary demand bounds and base stock policies. Hence, we can apply existing models from supply chain analytics to find the optimal safety levels of nurse staffing. We use a case study with real data to demonstrate that there are significant benefits from the inclusion of the forecast process when determining the optimal safety stocks. PMID:26340239

  14. Development of the NIREX generic transport safety assessment to assist in the provision of waste packaging advice

    International Nuclear Information System (INIS)

    The current Nirex Mission is to provide the United Kingdom with safe, environmentally sound and publicly acceptable options for the long-term management of radioactive materials. As part of this role, Nirex has developed a phased deep geological disposal concept which is defined by six 'generic documents' that describe systems, processes and safety assessments that are not specific to any one location or geology. These generic documents give access to detailed information about the ideas and approaches that underpin the phased disposal concept, and have been published with an invitation to enter into dialogue with Nirex regarding these issues. The generic documents identify the requirements for an integrated transport system that would be necessary for the management of the intermediate-level (ILW) and low-level (LLW) wastes within Nirex's remit - the so-called reference case volume. This has involved Nirex in the development of transport hardware and associated safety reports and modelling and assessment tools for transport system logistics and system safety. Although the phased disposal concept is only one option for the long-term management of waste, the integrated transport system and associated modelling tools, is likely to be of equal relevance to other options. The safety assessment of the generic transport operation for the movement of ILW and LLW waste from waste producers' sites to a future radioactive waste disposal facility is described in one of the generic documents - the generic transport safety assessment (GTSA). The GTSA demonstrates that the transport operation is compliant with Nirex safety principles, and that the nuclear and non-nuclear risks to the public and workers from routine transport and from accidents are acceptable. This paper describes the types of risk that are calculated, and discusses the data requirements and calculation methodology. The verification and validation methodology is outlined, together with a discussion of the results

  15. CTAB-assisted synthesis of S@rGO composite with enhanced photocatalytic activity and photostability

    Science.gov (United States)

    Hu, Changyuan; Zheng, Shizheng; Lian, Chengjiang; Hu, Quanhong; Duo, Shuwang; Zhang, Rongbin; Chen, Fei

    2015-04-01

    S@rGO(reduced graphene oxide) composites were synthesized by a facile electrostatic attraction in the presence of cetyltriethylammnonium bromide (CTAB). Scanning electron microscopy images show that sulfur particles were wrapped by a thin layer of rGO. The rGO nanocoating enhanced the absorption of visible light, facilitated the separation of photogenerated charges, promoted the adsorption of dye moleculars, and provided the perfect chemical protection to inner sulfur particles. As a result, the rGO nanocoating improved the photocatalytic activity and photostability of the sulfur photocatalyst for the degradation of methylene blue under simulated solar light irradiation. Our results might open up a promising way to develop stable and highly efficient sulfur-based photocatalyst.

  16. Enhanced random lasing in ZnO nanocombs assisted by Fabry-Perot resonance.

    Science.gov (United States)

    Chen, Yungting; Chen, Yangfang

    2011-04-25

    The ultraviolet random lasing behavior of an ensemble of ZnO nanocombs has been demonstrated. It is found that the Fabry-Perot resonance induced by nanocomb geometry can greatly enhance random lasing action with a low threshold condition. Besides, the emission spectra exhibit few sharp lasing peaks with a full width at half maximum (FWHM) of less than 0.3 nm and a narrow background emission with a FWHM of about 5 nm. Cathodoluminescence mapping images are utilized to analyze the Fabry-Perot resonance phenomenon. The resonant effect on the lasing system is further confirmed by nanocombs with different resonant cavity lengths. The unique lasing behavior induced by the simultaneous occurrence of Fabry-Perot resonance and random laser action shown here may open up a new possibility for the creation of highly efficient light emitting devices.

  17. Microjet-assisted dye-enhanced diode laser ablation of cartilaginous tissue

    Science.gov (United States)

    Pohl, John; Bell, Brent A.; Motamedi, Massoud; Frederickson, Chris J.; Wallace, David B.; Hayes, Donald J.; Cowan, Daniel

    1994-08-01

    Recent studies have established clinical application of laser ablation of cartilaginous tissue. The goal of this study was to investigate removal of cartilaginous tissue using diode laser. To enhance the interaction of laser light with tissue, improve the ablation efficiency and localize the extent of laser-induced thermal damage in surrounding tissue, we studied the use of a novel delivery system developed by MicroFab Technologies to dispense a known amount of Indocyanine Green (ICG) with a high spatial resolution to alter the optical properties of the tissue in a controlled fashion. Canine intervertebral disks were harvested and used within eight hours after collection. One hundred forty nL of ICG was topically applied to both annulus and nucleus at the desired location with the MicroJet prior to each irradiation. Fiber catheters (600 micrometers ) were used and positioned to irradiate the tissue with a 0.8 mm spot size. Laser powers of 3 - 10 W (Diomed, 810 nm) were used to irradiate the tissue with ten pulses (200 - 500 msec). Discs not stained with ICG were irradiated as control samples. Efficient tissue ablation (80 - 300 micrometers /pulse) was observed using ICG to enhance light absorption and confine thermal damage while there was no observable ablation in control studied. The extent of tissue damage observed microscopically was limited to 50 - 100 micrometers . The diode laser/Microjet combination showed promise for applications involving removal of cartilaginous tissue. This procedure can be performed using a low power compact diode laser, is efficient, and potentially more economical compared to procedures using conventional lasers.

  18. Surface-Enhanced Raman Spectroscopy Assisted by Radical Capturer for Tracking of Plasmon-Driven Redox Reaction

    Science.gov (United States)

    Yan, Xuefeng; Wang, Lingzhi; Tan, Xianjun; Tian, Baozhu; Zhang, Jinlong

    2016-07-01

    The deep understanding about the photocatalytic reaction induced by the surface plasmon resonance (SPR) effect is desirable but remains a considerable challenge due to the ultrafast relaxation of hole-electron exciton from SPR process and a lack of an efficient monitoring system. Here, using the p-aminothiophenol (PATP) oxidation SPR-catalyzed by Ag nanoparticle as a model reaction, a radical-capturer-assisted surface-enhanced Raman spectroscopy (SERS) has been used as an in-situ tracking technique to explore the primary active species determining the reaction path. Hole is revealed to be directly responsible for the oxidation of PATP to p, p‧-dimercaptoazobenzene (4, 4‧-DMAB) and O2 functions as an electron capturer to form isolated hole. The oxidation degree of PATP can be further enhanced through a joint utilization of electron capturers of AgNO3 and atmospheric O2, producing p-nitrothiophenol (PNTP) within 10 s due to the improved hole-electron separation efficiency.

  19. Biomolecule-assisted Solvothermal Synthesis and Enhanced Visible Light Photocatalytic Performance of Bi2S3/BiOCl Composites

    Institute of Scientific and Technical Information of China (English)

    JIA Zhimin; CHEN Wei; LIU Tianyu; HUANG Ting; LIU Xiaoheng

    2016-01-01

    Novel Bi2S3/BiOCl photocatalysts were successfully synthesized via a facile biomolecule-assisted solvothermal method and biomolecule L-cysteine was used as the sulfur source. The structures, morphology, and optical properties of the synthesized samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, transmission electron microscopy (TEM), and UV-vis diffuse reflectance spectroscopy (DRS). The presence of Bi2S3 in the Bi2S3/BiOCl composites could not only improve the optical properties but also enhance the photocatalytic activities for the degradation of Rhodamine B (RhB) under visible-light irradiation (λ > 420 nm) as compared with single Bi2S3 and BiOCl. Especially, the sample displayed the best performance of the photodegradation when the feed molar ratio of BiCl3 and L-cysteine was 2.4:1, which was about 10 times greater than that of pure BiOCl. The enhanced photocatalytic activities could be ascribed to the effective separation of photoinduced electrons and holes and the photosensitization of dye. Moreover, the possible photodegradation mechanism was also proposed, and the results revealed that the active holes (h+) and superoxide radicals (•O2−) were the main reactive species during photocatalytic degradation.

  20. Conceptual studies of construction and safety enhancement of ocean SMART mounted on GBS

    International Nuclear Information System (INIS)

    Highlights: • We suggested the concept of coupling the SMART to the GBS, and we made suggested improvements. • We describe the design concepts and GA of SMART ONPP. • We analyzed seismic feature of SMART ONPP preliminarily. • We suggested the concept of coupling the IPSS to the SMART ONPP, and we made suggested improvements. - Abstract: From the Fukushima accident, protection of NPPs from any imaginable natural disasters became very important. In this study, the authors suggest a new concept of ocean nuclear power plant (ONPP) by using SMART as a reference reactor, which is the most recent Small Modular Reactor (SMR) developed by Korea, to demonstrate that the proposed concept can improve the safety of NPP from earthquake and tsunami. The proposed concept utilizes Gravity Based Structure (GBS), which is a widely spread construction technique of offshore plants. Because, floating type or submerged type NPPs can be easily affected by severe ocean environments such as tsunamis and storms, additional safety features have to be added to the existing land based plant. In contrast, the newly proposed GBS-type ONPP does not require going through significant design modifications due to inherent characteristics of the construction method. The authors have demonstrated this concept can be applied to the large nuclear power plant in the previous work and will expand this concept for SMRs in this paper. The authors discuss the new concept by presenting design parameters, design requirements, and the new total general arrangement. Furthermore, due to the unique configuration of ONPP SMART, innovative passive safety features can be added to the existing SMART design. The performance of proposed concept to resist earthquake as well as newly added passive safety feature will be discussed by presenting simplified analysis results

  1. Conceptual studies of construction and safety enhancement of ocean SMART mounted on GBS

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Min-Gil, E-mail: gggggtt@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Lee, Kang-Heon, E-mail: welcome@kaist.ac.kr [Division of Ocean Systems Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Kim, Seong Gu, E-mail: skim07@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Woo, Il-Guk, E-mail: igwoo@dsme.co.kr [Department of Energy System R and D (Plant R and D), Daewoo Shipbuilding and Marine Engineering Co., Ltd., 221-17, Nonhyun-Dong, Gangnam-Gu, Seoul 135-010 (Korea, Republic of); Han, Jeong-Hoon, E-mail: jhhan1@dsme.co.kr [Department of Energy System R and D (Plant R and D), Daewoo Shipbuilding and Marine Engineering Co., Ltd., 221-17, Nonhyun-Dong, Gangnam-Gu, Seoul 135-010 (Korea, Republic of); Lee, Phill-Seung, E-mail: philseung@kaist.edu [Division of Ocean Systems Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Lee, Jeong Ik, E-mail: jeongiklee@kaist.ac.kr [Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu, Daejeon 305-701 (Korea, Republic of)

    2014-10-15

    Highlights: • We suggested the concept of coupling the SMART to the GBS, and we made suggested improvements. • We describe the design concepts and GA of SMART ONPP. • We analyzed seismic feature of SMART ONPP preliminarily. • We suggested the concept of coupling the IPSS to the SMART ONPP, and we made suggested improvements. - Abstract: From the Fukushima accident, protection of NPPs from any imaginable natural disasters became very important. In this study, the authors suggest a new concept of ocean nuclear power plant (ONPP) by using SMART as a reference reactor, which is the most recent Small Modular Reactor (SMR) developed by Korea, to demonstrate that the proposed concept can improve the safety of NPP from earthquake and tsunami. The proposed concept utilizes Gravity Based Structure (GBS), which is a widely spread construction technique of offshore plants. Because, floating type or submerged type NPPs can be easily affected by severe ocean environments such as tsunamis and storms, additional safety features have to be added to the existing land based plant. In contrast, the newly proposed GBS-type ONPP does not require going through significant design modifications due to inherent characteristics of the construction method. The authors have demonstrated this concept can be applied to the large nuclear power plant in the previous work and will expand this concept for SMRs in this paper. The authors discuss the new concept by presenting design parameters, design requirements, and the new total general arrangement. Furthermore, due to the unique configuration of ONPP SMART, innovative passive safety features can be added to the existing SMART design. The performance of proposed concept to resist earthquake as well as newly added passive safety feature will be discussed by presenting simplified analysis results.

  2. Non-Technical Skills (NTS) for enhancing patient safety: achievements and future directions

    OpenAIRE

    Kodate, Naonori; Ross, Anthony; Anderson, Janet E.; Flin, R

    2012-01-01

    Problems in team communication and decision making have been implicated in accidents in high risk industries such as aviation, off shore oil processing, nuclear power generation. Recognition of the role that breakdowns in communication and teamwork play in patient safety incidents has led to a plethora of studies in the area of what has come to be widely known as non-technical skills (NTS); a term initially used in European aviation (1). This has led to increasing interest in i...

  3. 46th annual meeting on nuclear technology (AMNT 2015). Key topic / Enhanced safety and operation excellence

    International Nuclear Information System (INIS)

    Summary report on the Technical Session ''Operation and Safety of Nuclear Installations, Fuel - Special Issues'' of the 46th Annual Conference on Nuclear Technology (AMNT 2015) held in Berlin, 5 to 7 May 2015. Other Sessions of AMNT 2015 have been covered in atw 7 to 12 (2015), 1 (2016) and will be covered in further issues of atw.

  4. A sequential-move game for enhancing safety and security cooperation within chemical clusters

    International Nuclear Information System (INIS)

    The present paper provides a game theoretic analysis of strategic cooperation on safety and security among chemical companies within a chemical industrial cluster. We suggest a two-stage sequential move game between adjacent chemical plants and the so-called Multi-Plant Council (MPC). The MPC is considered in the game as a leader player who makes the first move, and the individual chemical companies are the followers. The MPC's objective is to achieve full cooperation among players through establishing a subsidy system at minimum expense. The rest of the players rationally react to the subsidies proposed by the MPC and play Nash equilibrium. We show that such a case of conflict between safety and security, and social cooperation, belongs to the 'coordination with assurance' class of games, and we explore the role of cluster governance (fulfilled by the MPC) in achieving a full cooperative outcome in domino effects prevention negotiations. The paper proposes an algorithm that can be used by the MPC to develop the subsidy system. Furthermore, a stepwise plan to improve cross-company safety and security management in a chemical industrial cluster is suggested and an illustrative example is provided.

  5. A sequential-move game for enhancing safety and security cooperation within chemical clusters.

    Science.gov (United States)

    Pavlova, Yulia; Reniers, Genserik

    2011-02-15

    The present paper provides a game theoretic analysis of strategic cooperation on safety and security among chemical companies within a chemical industrial cluster. We suggest a two-stage sequential move game between adjacent chemical plants and the so-called Multi-Plant Council (MPC). The MPC is considered in the game as a leader player who makes the first move, and the individual chemical companies are the followers. The MPC's objective is to achieve full cooperation among players through establishing a subsidy system at minimum expense. The rest of the players rationally react to the subsidies proposed by the MPC and play Nash equilibrium. We show that such a case of conflict between safety and security, and social cooperation, belongs to the 'coordination with assurance' class of games, and we explore the role of cluster governance (fulfilled by the MPC) in achieving a full cooperative outcome in domino effects prevention negotiations. The paper proposes an algorithm that can be used by the MPC to develop the subsidy system. Furthermore, a stepwise plan to improve cross-company safety and security management in a chemical industrial cluster is suggested and an illustrative example is provided. PMID:21146296

  6. Enhancing the formation of tetragonal phase in perovskite nanocrystals using an ultrasound assisted wet chemical method.

    Science.gov (United States)

    Moghtada, Abdolmajid; Ashiri, Rouholah

    2016-11-01

    Synthesis of highly-pure tetragonal perovskite nanocrystals is the key challenge facing the development of new electronic devices. Our results have indicated that ultrasonication is able in enhancing the formation of tetragonal phase in perovskite nanocrystals. In the current research, multicationic oxide perovskite (ATiO3; A: Ba, Sr, Ba0.6Sr0.4) nanopowders are synthesized successfully by a general methodology without a calcination step. The method is able to synthesize high-purity nanoscale ATiO3 (BaTiO3, SrTiO3, Ba0.6Sr0.4TiO3) with tetragonal symmetry at a lower temperature and in a shorter time span in contrast to the literature. To reach an in-depth understanding of the scientific basis of the proposed methodology, in-detail analysis was carried out via XRD, FTIR, FT-Raman, FE-SEM and HR-TEM. The effects of the sonication time and sonication (bath) temperature on the tetragonality of nanoscale products were examined. Furthermore, Raman spectroscopy provides clear evidence for local tetragonal symmetries, in particular when a band is observed at 310cm(-1). PMID:27245965

  7. Enhanced microwave absorption properties of CTAB assisted Pr-Cu substituted nanomaterial

    Science.gov (United States)

    Sadiq, Imran; Naseem, Shahzad; Riaz, Saira; Khan, Hasan M.; Ashiq, Muhammad Naeem; Hussain, S. Sajjad; Rana, Mazhar

    2016-09-01

    In this study, the rare earth Pr3+and divalent Cu2+ elements substituted Sr1-xPrxMn2Fe16-yCuyO27 (x=0, 0.02, 0.06, 0.1 and y=0, 0.1, 0.3, 0.5) W-type hexagonal ferrites were prepared by Sol-Gel method. TGA and DSC analysis of as prepared material was carried out to confirm the temperature at which required phase can be obtained. The XRD patterns exhibit the single phase for all the samples and the lattice parameters were changed with the additives. The absorption bands at wave number 636 and 554 cm-1 in FTIR spectrum indicate the stretching vibration of metal-oxygen ions which also ratifies the single phase for the prepared material. Microstructural analysis confirms the agglomeration of nanograins which leads to formation of platelet like structure which cause in the enhancement of the microwave absorption properties of material. The minimum reflection loss of -59.8 dB at 9.34 GHz frequency was observed makes the prepared material good candidate to be used in super high frequency application. The attenuation constant and reflectivity results are also in good agreement with minimum reflection losses results.

  8. Optoelectronic enhancement of monocrystalline silicon solar cells by porous silicon-assisted mechanical grooving

    Energy Technology Data Exchange (ETDEWEB)

    Ben Rabha, Mohamed; Mohamed, Seifeddine Belhadj; Dimassi, Wissem; Gaidi, Mounir; Ezzaouia, Hatem; Bessais, Brahim [Laboratoire de Photovoltaique, Centre de Recherches et des Technologies de l' Energie, Technopole de Borj-Cedria, BP 95, 2050 Hammam-Lif (Tunisia)

    2011-03-15

    One of the most important factors influencing silicon solar cells performances is the front side reflectivity. Consequently, new methods for efficient reduction of this reflectivity are searched. This has always been done by creating a rough surface that enables incident light of being absorbed within the solar cell. Combination of texturization-porous silicon surface treatment was found to be an attractive technical solution for lowering the reflectivity of monocrystalline silicon (c-Si). The texturization of the monocrystalline silicon wafer was carried out by means of mechanical grooving. A specific etching procedure was then applied to form a thin porous silicon layer enabling to remove mechanical damages. This simple and low cost method reduces the total reflectivity from 29% to 7% in the 300 - 950 nm wavelength range and enhances the diffusion length of the minority carriers from 100 {mu}m to 790 {mu}m (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  9. Development of reliability-based safety enhancement technology; development of organization concept model in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Chang Hyun; Kim, Ju Youl; Kim, Yoon Ik; Yang, Hui Chang; Lee, Yong Sik; Kim, Se Hyung [Seoul National University, Seoul (Korea)

    2002-03-01

    The influences of organizational factors on safety of nuclear power plants are mentioned in the early 1970s and noticed after being focused on in the accident report of TMI in 1979. These needs let us implement this research and the purposes of this research are to assess the organizational influences and to develop the organizational conceptual model to establish the basis of identifying the organizational factors, using this model to contribute to enhance safety and economics in nuclear power plants. Eventually research on the organizational influences is expected to have two effects, which are to improve safety through identifying potential causes of accidents and to elevate economics as a new approach to more efficient operation of nuclear power plants. In this study, recent studies were surveyed on the organizational conceptual model, the identification of organizational factors, assessment of organizational influences and evaluation methods of organizational factors and organizational influences among the overseas and domestic researches. In addition specific characteristics of domestic nuclear power plants were tried to identify through plant visit and an evaluation method of organizational influences on component maintenance and human performance were developed and presented. 71 refs., 40 figs., 18 tabs. (Author)

  10. Sensory subtraction in robot-assisted surgery: fingertip skin deformation feedback to ensure safety and improve transparency in bimanual haptic interaction.

    Science.gov (United States)

    Meli, Leonardo; Pacchierotti, Claudio; Prattichizzo, Domenico

    2014-04-01

    This study presents a novel approach to force feedback in robot-assisted surgery. It consists of substituting haptic stimuli, composed of a kinesthetic component and a skin deformation, with cutaneous stimuli only. The force generated can then be thought as a subtraction between the complete haptic interaction, cutaneous, and kinesthetic, and the kinesthetic part of it. For this reason, we refer to this approach as sensory subtraction. Sensory subtraction aims at outperforming other nonkinesthetic feedback techniques in teleoperation (e.g., sensory substitution) while guaranteeing the stability and safety of the system. We tested the proposed approach in a challenging 7-DoF bimanual teleoperation task, similar to the Pegboard experiment of the da Vinci Skills Simulator. Sensory subtraction showed improved performance in terms of completion time, force exerted, and total displacement of the rings with respect to two popular sensory substitution techniques. Moreover, it guaranteed a stable interaction in the presence of a communication delay in the haptic loop.

  11. Enzyme-assisted supercritical carbon dioxide extraction of black pepper oleoresin for enhanced yield of piperine-rich extract.

    Science.gov (United States)

    Dutta, Sayantani; Bhattacharjee, Paramita

    2015-07-01

    Black pepper (Piper nigrum L.), the King of Spices is the most popular spice globally and its active ingredient, piperine, is reportedly known for its therapeutic potency. In this work, enzyme-assisted supercritical carbon dioxide (SC-CO2) extraction of black pepper oleoresin was investigated using α-amylase (from Bacillus licheniformis) for enhanced yield of piperine-rich extract possessing good combination of phytochemical properties. Optimization of the extraction parameters (without enzyme), mainly temperature and pressure, was conducted in both batch and continuous modes and the optimized conditions that provided the maximum yield of piperine was in the batch mode, with a sample size of 20 g of black pepper powder (particle diameter 0.42 ± 0.02 mm) at 60 °C and 300 bar at 2 L/min of CO2 flow. Studies on activity of α-amylase were conducted under these optimized conditions in both batch and continuous modes, with varying amounts of lyophilized enzyme (2 mg, 5 mg and 10 mg) and time of exposure of the enzyme to SC-CO2 (2.25 h and 4.25 h). The specific activity of the enzyme increased by 2.13 times when treated in the continuous mode than in the batch mode (1.25 times increase). The structural changes of the treated enzymes were studied by (1)H NMR analyses. In case of α-amylase assisted extractions of black pepper, both batch and continuous modes significantly increased the yields and phytochemical properties of piperine-rich extracts; with higher increase in batch mode than in continuous. PMID:25617183

  12. Enzyme-assisted supercritical carbon dioxide extraction of black pepper oleoresin for enhanced yield of piperine-rich extract.

    Science.gov (United States)

    Dutta, Sayantani; Bhattacharjee, Paramita

    2015-07-01

    Black pepper (Piper nigrum L.), the King of Spices is the most popular spice globally and its active ingredient, piperine, is reportedly known for its therapeutic potency. In this work, enzyme-assisted supercritical carbon dioxide (SC-CO2) extraction of black pepper oleoresin was investigated using α-amylase (from Bacillus licheniformis) for enhanced yield of piperine-rich extract possessing good combination of phytochemical properties. Optimization of the extraction parameters (without enzyme), mainly temperature and pressure, was conducted in both batch and continuous modes and the optimized conditions that provided the maximum yield of piperine was in the batch mode, with a sample size of 20 g of black pepper powder (particle diameter 0.42 ± 0.02 mm) at 60 °C and 300 bar at 2 L/min of CO2 flow. Studies on activity of α-amylase were conducted under these optimized conditions in both batch and continuous modes, with varying amounts of lyophilized enzyme (2 mg, 5 mg and 10 mg) and time of exposure of the enzyme to SC-CO2 (2.25 h and 4.25 h). The specific activity of the enzyme increased by 2.13 times when treated in the continuous mode than in the batch mode (1.25 times increase). The structural changes of the treated enzymes were studied by (1)H NMR analyses. In case of α-amylase assisted extractions of black pepper, both batch and continuous modes significantly increased the yields and phytochemical properties of piperine-rich extracts; with higher increase in batch mode than in continuous.

  13. Robot-Assisted Proprioceptive Training with Added Vibro-Tactile Feedback Enhances Somatosensory and Motor Performance

    Science.gov (United States)

    Cuppone, Anna Vera; Squeri, Valentina; Semprini, Marianna; Masia, Lorenzo; Konczak, Jürgen

    2016-01-01

    This study examined the trainability of the proprioceptive sense and explored the relationship between proprioception and motor learning. With vision blocked, human learners had to perform goal-directed wrist movements relying solely on proprioceptive/haptic cues to reach several haptically specified targets. One group received additional somatosensory movement error feedback in form of vibro-tactile cues applied to the skin of the forearm. We used a haptic robotic device for the wrist and implemented a 3-day training regimen that required learners to make spatially precise goal-directed wrist reaching movements without vision. We assessed whether training improved the acuity of the wrist joint position sense. In addition, we checked if sensory learning generalized to the motor domain and improved spatial precision of wrist tracking movements that were not trained. The main findings of the study are: First, proprioceptive acuity of the wrist joint position sense improved after training for the group that received the combined proprioceptive/haptic and vibro-tactile feedback (VTF). Second, training had no impact on the spatial accuracy of the untrained tracking task. However, learners who had received VTF significantly reduced their reliance on haptic guidance feedback when performing the untrained motor task. That is, concurrent VTF was highly salient movement feedback and obviated the need for haptic feedback. Third, VTF can be also provided by the limb not involved in the task. Learners who received VTF to the contralateral limb equally benefitted. In conclusion, somatosensory training can significantly enhance proprioceptive acuity within days when learning is coupled with vibro-tactile sensory cues that provide feedback about movement errors. The observable sensory improvements in proprioception facilitates motor learning and such learning may generalize to the sensorimotor control of the untrained motor tasks. The implications of these findings for

  14. Surgical innovation-enhanced quality and the processes that assure patient/provider safety: A surgical conundrum.

    Science.gov (United States)

    Bruny, Jennifer; Ziegler, Moritz

    2015-12-01

    Innovation is a crucial part of surgical history that has led to enhancements in the quality of surgical care. This comprises both changes which are incremental and those which are frankly disruptive in nature. There are situations where innovation is absolutely required in order to achieve quality improvement or process improvement. Alternatively, there are innovations that do not necessarily arise from some need, but simply are a new idea that might be better. All change must assure a significant commitment to patient safety and beneficence. Innovation would ideally enhance patient care quality and disease outcomes, as well stimulate and facilitate further innovation. The tensions between innovative advancement and patient safety, risk and reward, and demonstrated effectiveness versus speculative added value have created a contemporary "surgical conundrum" that must be resolved by a delicate balance assuring optimal patient/provider outcomes. This article will explore this delicate balance and the rules that govern it. Recommendations are made to facilitate surgical innovation through clinical research. In addition, we propose options that investigators and institutions may use to address competing priorities.

  15. Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion

    Directory of Open Access Journals (Sweden)

    Khayat Andre

    2011-01-01

    Full Text Available Abstract We challenge the hypothesis of enhanced myocardial reperfusion after implanting a left ventricular assist device together with bone marrow mononuclear stem cells in patients with end-stage ischemic cardiomyopathy. Irreversible myocardial loss observed in ischemic cardiomyopathy leads to progressive cardiac remodelling and dysfunction through a complex neurohormonal cascade. New generation assist devices promote myocardial recovery only in patients with dilated or peripartum cardiomyopathy. In the setting of diffuse myocardial ischemia not amenable to revascularization, native myocardial recovery has not been observed after implantation of an assist device as destination therapy. The hybrid approach of implanting autologous bone marrow stem cells during assist device implantation may eventually improve native cardiac function, which may be associated with a better prognosis eventually ameliorating the need for subsequent heart transplantation. The aforementioned hypothesis has to be tested with well-designed prospective multicentre studies.

  16. Safety enhancement of Kozloduy NPP units 5 and 6 using PSA-1 and other studies

    International Nuclear Information System (INIS)

    The paper describes briefly the background, objectives and organisation of the Kozloduy NPP 'Upgrading Programme for Units 5 and 6' developed in 1994. The classical probabilistic safety analysis (level 1) of these units have been used as criteria for evaluation of the changes already made. This PSA-1 study is the first of the kind for WWER-1000 reactors. It is based on a methodology of IAEA and includes internal and external initiators of accidents. Results from seismic probabilistic risk assessments are also reported. (author)

  17. First wall and blanket module safety enhancement by material selection and design decision

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, B.J.

    1980-01-01

    A thermal/mechanical study has been performed which illustrates the behavior of a fusion reactor first wall and blanket module during a loss of coolant flow event. The relative safety advantages of various material and design options were determined. A generalized first wall-blanket concept was developed to provide the flexibility to vary the structural material (stainless steel vs titanium), coolant (helium vs water), and breeder material (liquid lithium vs solid lithium aluminate). In addition, independent vs common first wall-blanket cooling and coupled adjacent module cooling design options were included in the study. The comparative analyses were performed using a modified thermal analysis code to handle phase change problems.

  18. Visit safety

    CERN Multimedia

    2012-01-01

    Experiment areas, offices, workshops: it is possible to have co-workers or friends visit these places.     You already know about the official visits service, the VIP office, and professional visits. But do you know about the safety instruction GSI-OHS1, “Visits on the CERN site”? This is a mandatory General Safety Instruction that was created to assist you in ensuring safety for all your visits, whatever their nature—especially those that are non-official. Questions? The HSE Unit will be happy to answer them. Write to safety-general@cern.ch.   The HSE Unit

  19. Effect of Ag/Au bilayer assisted etching on the strongly enhanced photoluminescence and visible light photocatalysis by Si nanowire arrays.

    Science.gov (United States)

    Ghosh, Ramesh; Imakita, Kenji; Fujii, Minoru; Giri, P K

    2016-03-21

    We report on the strongly enhanced photoluminescence (PL) and visible light photocatalysis by arrays of vertically aligned single crystalline Si nanowires (NWs) grown by Ag/Au bilayer assisted etching. High resolution FESEM and TEM imaging reveals that the Si NWs are decorated with ultra-small size arbitrary shaped Si nanocrystals (NCs) due to the lateral etching of the NWs. A strong broad band and tunable visible to near-infrared (NIR) photoluminescence (PL) in the range 1.3-2.4 eV are observed for these Si NWs/NCs at room temperature, depending on the etching conditions. Our studies reveal that the visible-NIR PL intensity is about two orders of magnitude higher and it exhibits faster decay dynamics in the bilayer assisted etching case as compared to the Ag or Au single layer etching case. The enhanced PL in the bimetal case is attributed to the longer length and higher density of the Si NWs/NCs, surface plasmon resonance enhanced absorption by residual bimetal NPs and the enhanced radiative recombination rate. Studies on the time evolution of PL spectral features with laser exposure under ambient conditions and laser power dependence reveal that both the quantum confinement of carriers in Si NCs and the nonbridging oxygen hole defects in the SiOx layer contribute to the tunable PL. Interestingly, Si NWs grown by Ag/Au bilayer assisted etching exhibit enhanced photocatalytic degradation of methylene blue in comparison to Si NWs grown by single layer Ag or Au assisted etching. The Schottky barrier present between bimetallic NPs and nanoporous Si NWs with Si-H bonds facilitates the photocatalytic activity by efficient separation of photogenerated e-h pairs. Our results demonstrate the superiority of the Si NW array grown by bilayer assisted etching for their cutting edge applications in optoelectronics and environmental cleaning.

  20. Novel biopreservatives to enhance the safety and quality of strawberry juice.

    Science.gov (United States)

    Tomadoni, B; Viacava, G; Cassani, L; Moreira, M R; Ponce, A

    2016-01-01

    Pomegranate extract, vanillin and geraniol were studied as natural antimicrobials on strawberry juice. Strawberry juice was treated with each agent at two concentrations: pomegranate extract at 180 and 360 μg/mL; vanillin at 2.5 and 5 mg/mL; and geraniol at 0.6 and 1.2 μL/mL. After being treated, juices were stored at 5 °C and microbiological, physicochemical and sensory studies were carried out. Also, a second batch of juice was inoculated with Escherichia coli O157:H7 (10(5) CFU/mL) before being treated, to safety study. Geraniol and vanillin, at both concentrations tested, were highly effective in reducing the native microflora on strawberry juice (more than 3 log cycles), extending the microbiological shelf-life of the product. Moreover, both antimicrobials improved the product safety by reducing inoculated E. coli O157:H7. Furthermore, vanillin showed a significant increase in polyphenol content compared to untreated juice. On the other hand, pomegranate extract applied at the highest concentration showed important reductions on mesophilic and psychrophilic bacteria, but no effect on yeast and molds and inoculated E. coli. Even though vanillin and geraniol incorporation on strawberry juice had a negative effect on its sensory quality, pomegranate extract had no impact on the sensory attributes evaluated. Combinations of the biopreservatives could be studied in order to decrease the concentration of the antimicrobials, reducing the effects on strawberry juice sensory characteristics. PMID:26787948

  1. Enhanced photocatalytic activity of CeO2 using β-cyclodextrin on visible light assisted decoloration of methylene blue.

    Science.gov (United States)

    Pitchaimuthu, Sakthivel; Velusamy, Ponnusamy

    2014-01-01

    An attempt has been made to enhance the photocatalytic activity of CeO(2) for visible light assisted decoloration of methylene blue (MB) dye in aqueous solutions by β-cyclodextrin (β-CD). The inclusion complexation patterns between host and guest (i.e., β-CD and MB) have been confirmed with UV-visible spectral data. The interaction between CeO(2) and β-CD has also been characterized by field emission scanning electron microscopy analysis. The photocatalytic activity of the catalyst under visible light was investigated by measuring the photodegradation of MB in aqueous solution. The effects of key operational parameters such as initial dye concentration, initial pH, CeO(2) concentration as well as illumination time on the decolorization extents were investigated. Among the processing parameters, the pH of the reaction solution played an important role in tuning the photocatalytic activity of CeO(2). The maximum photodecoloration rate was achieved at basic pH (pH 11). Under the optimum operational conditions, approximately 99.6% dye removal was achieved within 120 min. The observed results indicate that the decolorization of the MB followed a pseudo-first order kinetics. PMID:24434976

  2. Nitrogen-Doped Carbon Nanotube Spherical Particles for Supercapacitor Applications: Emulsion-Assisted Compact Packing and Capacitance Enhancement.

    Science.gov (United States)

    Gueon, Donghee; Moon, Jun Hyuk

    2015-09-16

    The combination of the control of CNT assembly density and the control of intrinsic carbon properties by doping can synergistically improve the supercapacitor performance of CNT-based electrodes. We prepared a dense-packed CNT spherical assembly via emulsion-assisted evaporation and subsequently conducted nitrogen (N) doping to make CNT-based supercapacitors. The assembly of CNT spherical particles is applied as the supercapacitor electrode. We control the N doping content and obtain a specific capacity of 215 F/g at a current density of 0.2 A/g, which is 3.1 times higher than that of the untreated sample. The enhancement stems from high pseudocapacitance and high electrical conductivity that result from the N doping of the CNT assembly. In a comparison of the specific capacitance of N-CNT spherical particles with that of the CNT films prepared by conventional solution-coating, we found that N-CNT samples display a capacitance that is 1.8 times higher, thus confirming the morphological advantage provided by the CNT packing and the hierarchical porous structure in the CNT particle assembly. Our approach allows a facile and high throughput production of high performance electrodes based on CNTs that are commercially available. Moreover, our approach can be extended to produce spherical particles consisting of other nanostructured carbon materials and their composites.

  3. Enhancement in Figure of Merit ( ZT) by Annealing of BiTe Nanostructures Synthesized by Microwave-Assisted Flash Combustion

    Science.gov (United States)

    Kaur, Harjeet; Sharma, Lalit; Singh, Simrjit; Sivaiah, Bathula; Reddy, G. B.; Senguttuvan, T. D.

    2014-06-01

    Uniform polycrystalline bismuth telluride (BiTe) nanowires of diameter 100 nm to 150 nm and hexagonal nanoplates with thickness of 50 nm to 100 nm have been successfully synthesized by the microwave-assisted flash combustion technique. The formation of BiTe nanostructures depends on the type of fuel and the oxidant-to-fuel ratio, which in turn affect the reaction time and reaction temperature. Spark plasma sintering has been employed for compaction and sintering of both as-synthesized as well as annealed BiTe powders. Increasing the sintering temperature while using faster sintering cycles reduced the porosity, resulting in high densification while preserving the nanostructures. The dimensionless figure of merit ( ZT) was evaluated from the Seebeck coefficient, electrical resistivity, and thermal conductivity values over the range from 300 K to 600 K. The effect of annealing on the enhancement of ZT is discussed. These evaluations suggest that the rarely studied BiTe is a potential candidate for thermoelectric applications at low temperatures.

  4. Twitter as a tool to enhance student engagement during an interprofessional patient safety course.

    Science.gov (United States)

    Mckay, Mary; Sanko, Jill Steiner; Shekhter, Ilya; Birnbach, David J

    2014-11-01

    Twitter and other social media forums are gaining popularity in both the academic and conference arenas as tools to increase participant engagement, attention and interaction. While Twitter has been used successfully to engage college students, it has not been explored for use in an interprofessional curriculum. We sought to explore it as a method to foster student engagement. During a weeklong interprofessional patient safety course we invited students and faculty to participate in a Twitter conversation. It was found that this form of social media successfully captured a "behind the scenes" conversation and the experiences of the students which would have not been otherwise captured. This information is guiding future interprofessional educational programming in both the medical and nursing schools.

  5. [Further enhance the long-term myopia control efficacy and safety of orthokeratology].

    Science.gov (United States)

    Xie, Peiying

    2014-01-01

    Strategies and methods of myopia prevention and control has been more and more. In recent years optical correction method is focusing on promoting the retinal mid-peripheral myopic defocus, improving the visual quality and promoting the accommodative function. Among the all, orthokeratology is the most notable optometry technology. This article will combine research progress both local and international achievements, the present situation of the domestic popularized the technique, and the existing problems. From the realistic approach, keep improving, the pursuit of stability, the pursuit of harmony and eliminate the false five aspects, to discuss how to promote orthokeratology for the myopia control with long-term stably efficacy and safety. How to promote the harmony and cooperation between doctors, patients and manufactures. And how to correctly guide the orthokeratology Having both specification and continued development. PMID:24709125

  6. Extracellular control of intracellular drug release for enhanced safety of anti-cancer chemotherapy

    Science.gov (United States)

    Zhu, Qian; Qi, Haixia; Long, Ziyan; Liu, Shang; Huang, Zhen; Zhang, Junfeng; Wang, Chunming; Dong, Lei

    2016-06-01

    The difficulty of controlling drug release at an intracellular level remains a key challenge for maximising drug safety and efficacy. We demonstrate herein a new, efficient and convenient approach to extracellularly control the intracellular release of doxorubicin (DOX), by designing a delivery system that harnesses the interactions between the system and a particular set of cellular machinery. By simply adding a small-molecule chemical into the cell medium, we could lower the release rate of DOX in the cytosol, and thereby increase its accumulation in the nuclei while decreasing its presence at mitochondria. Delivery of DOX with this system effectively prevented DOX-induced mitochondria damage that is the main mechanism of its toxicity, while exerting the maximum efficacy of this anti-cancer chemotherapeutic agent. The present study sheds light on the design of drug delivery systems for extracellular control of intracellular drug delivery, with immediate therapeutic implications.

  7. High Energy Density Additives for Hybrid Fuel Rockets to Improve Performance and Enhance Safety

    Science.gov (United States)

    Jaffe, Richard L.

    2014-01-01

    We propose a conceptual study of prototype strained hydrocarbon molecules as high energy density additives for hybrid rocket fuels to boost the performance of these rockets without compromising safety and reliability. Use of these additives could extend the range of applications for which hybrid rockets become an attractive alternative to conventional solid or liquid fuel rockets. The objectives of the study were to confirm and quantify the high enthalpy of these strained molecules and to assess improvement in rocket performance that would be expected if these additives were blended with conventional fuels. We confirmed the chemical properties (including enthalpy) of these additives. However, the predicted improvement in rocket performance was too small to make this a useful strategy for boosting hybrid rocket performance.

  8. Use of artificial intelligence to enhance the safety of nuclear power plants

    International Nuclear Information System (INIS)

    In the operation of a nuclear power plant, the sheer magnitude of the number of process parameters and systems interactions poses difficulties for the operators, particularly during abnormal or emergency situations. Recovery from an upset situation depends upon the facility with which the available raw data can be converted into and assimilated as meaningful knowledge. Plant personnel are sometimes affected by stress and emotion, which may have varying degrees of influence on their performance. Expert systems can take some of the uncertainty and guesswork out of their decisions by providing expert advice and rapid access to a large information base. Application of artificial intelligence technologies, particularly expert systems, to control room activities in a nuclear power plant has the potential to reduce operator error and improve power plant safety and reliability

  9. Use of artificial intelligence to enhance the safety of nuclear power plants

    International Nuclear Information System (INIS)

    In the operation of a nuclear power plant, the sheer magnitude of the number of process parameters and systems interactions poses difficulties for the operators, particularly during abnormal or emergency situations. Recovery from an upset situation depends upon the facility with which the available raw data can be converted into and assimilated as meaningful knowledge. Plant personnel are sometimes affected by stress and emotion, which may have varying degrees of influence on their performance. Expert systems can take some of the uncertainty and guesswork out of their decisions by providing expert advice and rapid access to a large information base. Application of artificial intelligence technologies, particularly expert systems, to control room activities in a nuclear power plant has the potential to reduce operator error and improve power plant safety and reliability. 12 refs

  10. Categorization of Radioactive Sources. Safety Guide

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and I continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the Contracting Parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  11. International cooperation for the development of consistent and stable transportation regulations to promote and enhance safety and security

    International Nuclear Information System (INIS)

    International commerce of radioactive materials crosses national boundaries, linking separate regulatory institutions with a common purpose and making it necessary for these institutions to work together in order to achieve common safety goals in a manner that does not place an undue burden on industry and commerce. Widespread and increasing use of radioactive materials across the world has led to increases in the transport of radioactive materials. The demand for consistency in the oversight of international transport has also increased to prevent unnecessary delays and costs associated with incongruent or redundant regulatory requirements by the various countries through which radioactive material is transported. The International Atomic Energy Agency (IAEA) is the authority for international regulation of transportation of radioactive materials responsible for promulgation of regulations and guidance for the establishment of acceptable methods of transportation for the international community. As such, the IAEA is seen as the focal point for consensus building between its Member States to develop consistency in transportation regulations and reviews and to ensure the safe and secure transport of radioactive material. International cooperation is also needed to ensure stability in our regulatory processes. Changes to transportation regulations should be based on an anticipated safety benefit supported by risk information and insights gained from continuing experience, evaluation, and research studies. If we keep safety as the principle basis for regulatory changes, regulatory stability will be enhanced. Finally, as we endeavour to maintain consistency and stability in our international regulations, we must be mindful of the new security challenges that lay before the international community as a result of a changing terrorist environment. Terrorism is a problem of global concern that also requires international cooperation and support, as we look for ways to

  12. Antioxidant-Enhancing Property of the Polar Fraction of Mangosteen Pericarp Extract and Evaluation of Its Safety in Humans

    Science.gov (United States)

    Numpraphrut, Pornpayom; Charoensakdi, Ratiya; Neungton, Neelobol; Tunrungruangtavee, Vachara; Jaisupa, Nattapon; Charoensak, Suwit

    2016-01-01

    Crude extract from the pericarp of the mangosteen (mangosteen extract [ME]) has exhibited several medicinal properties in both animal models and human cell lines. Interestingly, the cytotoxic activities were always observed in nonpolar fraction of the extract whereas the potent antioxidant was often found in polar fraction. Although it has been demonstrated that the polar fraction of ME exhibited the antioxidant activity, the safety of the polar fraction of ME has never been thoroughly investigated in humans. In this study, we investigated the safety of oral administration of the polar fraction of ME in 11 healthy Thai volunteers. During a 24-week period of the study, only minor and tolerable side effects were reported; no serious side effects were documented. Blood chemistry studies also showed no liver damage or kidney dysfunction in all subjects. We also demonstrated antioxidant property of the polar fraction of ME both in vitro and in vivo. Interestingly, oral administration of the polar fraction of ME enhanced the antioxidant capability of red blood cells and decreased oxidative damage to proteins within red blood cells and whole blood. PMID:27703599

  13. Antioxidant-Enhancing Property of the Polar Fraction of Mangosteen Pericarp Extract and Evaluation of Its Safety in Humans

    Directory of Open Access Journals (Sweden)

    Wichit Suthammarak

    2016-01-01

    Full Text Available Crude extract from the pericarp of the mangosteen (mangosteen extract [ME] has exhibited several medicinal properties in both animal models and human cell lines. Interestingly, the cytotoxic activities were always observed in nonpolar fraction of the extract whereas the potent antioxidant was often found in polar fraction. Although it has been demonstrated that the polar fraction of ME exhibited the antioxidant activity, the safety of the polar fraction of ME has never been thoroughly investigated in humans. In this study, we investigated the safety of oral administration of the polar fraction of ME in 11 healthy Thai volunteers. During a 24-week period of the study, only minor and tolerable side effects were reported; no serious side effects were documented. Blood chemistry studies also showed no liver damage or kidney dysfunction in all subjects. We also demonstrated antioxidant property of the polar fraction of ME both in vitro and in vivo. Interestingly, oral administration of the polar fraction of ME enhanced the antioxidant capability of red blood cells and decreased oxidative damage to proteins within red blood cells and whole blood.

  14. Feature-level fusion of laser scanner and video data for advanced driver assistance systems

    OpenAIRE

    Kämpchen, Nico

    2007-01-01

    Advanced driver assistance systems aim at an improved traffic safety, enhanced comfort and driving pleasure. Sensors perceive the objects surrounding the vehicle and produce an environment description. The assistance systems support the driver by assessing the situation recognized by this vehicle environment description. Current research in the area of advanced driver assistance systems aims at increased functionality. Comfort systems, such as the ACC, are expected to support the driver not o...

  15. Using swarm intelligence to boost the root cause analysis process and enhance patient safety.

    Science.gov (United States)

    2016-03-01

    In an effort to strengthen patient safety, leadership at the University of Kentucky HealthCare (UKHC) decided to replace its traditional approach to root cause analysis (RCA) with a process based on swarm intelligence, a concept borrowed from other industries. Under this process, when a problem or error is identified, staff quickly hold a swarm--a meeting in which all those involved in the incident or problem quickly evaluate why the issue occurred and identify potential solutions for implementation. A pillar of the swarm concept is a mandate that there be no punishments or finger-pointing during the swarms. The idea is to encourage staff to be forthcoming to achieve effective solutions. Typically, swarms last for one hour and result in action plans designed to correct problems or deficiencies within a specific period of time. The ED was one of the first areas where UKHC applied swarms. For example, hospital administrators note that the approach has been used to address issues involving patient flow, triage protocols, assessments, overcrowding, and boarding. After seven years, incident reporting at UKHC has increased by 52%, and the health system has experienced a 37% decrease in the observed-to-expected mortality ratio.

  16. An Enhanced OFDM Resource Allocation Algorithm in C-RAN Based 5G Public Safety Network

    Directory of Open Access Journals (Sweden)

    Lei Feng

    2016-01-01

    Full Text Available Public Safety Network (PSN is the network for critical communication when disaster occurs. As a key technology in 5G, Cloud-Radio Access Network (C-RAN can play an important role in PSN instead of LTE-based RAN. This paper firstly introduces C-RAN based PSN architecture and models the OFDM resource allocation problem in C-RAN based PSN as an integer quadratic programming, which allows the trade-off between expected bitrates and allocating fairness of PSN Service User (PSU. However, C-RAN based PSN needs to improve the efficiency of allocating algorithm because of a mass of PSU-RRH associations when disaster occurs. To deal with it, the resources allocating problem with integer variables is relaxed into one with continuous variables in the first step and an algorithm based on Generalized Bender’s Decomposition (GBD is proposed to solve it. Then we use Feasible Pump (FP method to get a feasible integer solution on the original OFDM resources allocation problem. The final experiments show the total throughput achieved by C-RAN based PSN is at most higher by 19.17% than the LTE-based one. And the average computational time of the proposed GBD and FP algorithm is at most lower than Barrier by 51.5% and GBD with no relaxation by 30.1%, respectively.

  17. RETROSPECTIVE ANALYSIS: TO ENHANCE PATIENT SAFETY BY MINIMIZING MEDICATION ERRORS IN TERTIARY CARE CARDIAC HOSPITAL

    Directory of Open Access Journals (Sweden)

    Lal Sukhbir

    2012-09-01

    Full Text Available To identify and measure the frequency of medication errors, to understand the causes for errors and best strategies to decrease medication errors rate in a cardiac hospital New Delhi. The Retrospective study of 137 case files, was undertaken to find out the medication errors in new drugs to be included in hospital formulary and to study policy compliances,for the period of a month, February 2010.We studied 137 patient files and Medication error related were reported most often at the stages of prescription- 32 cases(23.35%, 12 administration errors(8.75%, 9 documentation errors(6.56%, 7 transcription errors (5.1%. This study has demonstrated a whole range of different types of errors in different phases of medication use and documentation process. We have seen that handwritten prescriptions are associated with large number of errors. A combined effort is required by the physician’s, managerial staff, nursing staff and educational interventions to improve patient safety in hospital.KEY WORDS:

  18. Using swarm intelligence to boost the root cause analysis process and enhance patient safety.

    Science.gov (United States)

    2016-03-01

    In an effort to strengthen patient safety, leadership at the University of Kentucky HealthCare (UKHC) decided to replace its traditional approach to root cause analysis (RCA) with a process based on swarm intelligence, a concept borrowed from other industries. Under this process, when a problem or error is identified, staff quickly hold a swarm--a meeting in which all those involved in the incident or problem quickly evaluate why the issue occurred and identify potential solutions for implementation. A pillar of the swarm concept is a mandate that there be no punishments or finger-pointing during the swarms. The idea is to encourage staff to be forthcoming to achieve effective solutions. Typically, swarms last for one hour and result in action plans designed to correct problems or deficiencies within a specific period of time. The ED was one of the first areas where UKHC applied swarms. For example, hospital administrators note that the approach has been used to address issues involving patient flow, triage protocols, assessments, overcrowding, and boarding. After seven years, incident reporting at UKHC has increased by 52%, and the health system has experienced a 37% decrease in the observed-to-expected mortality ratio. PMID:26979047

  19. Nuclear criticality safety and time reactivity enhancement aspects of energy amplifier system devices

    Energy Technology Data Exchange (ETDEWEB)

    Siciliano, F. [ENEA, Centro Ricerche Trisaia, Rotondelle, Matera (Italy). Direzione INFO

    1995-12-01

    As far as the Rubbia`s and colleagues proposal of innovating Energy Amplifier system (E.A.s.) device driven by a particle beam accelerator is concerned, four basic topics are comprised in the present paper: (1) A short outline of the nuclear aspects of Th-U and U-Pu fuel cycles regarding their general breeding and efficiency features. (2) The needed nuclear criticality control requirements have been studied in terms of safety regulating parameters on the basis of the ThO2 mixed oxides selected as fuel kind for the E.A.s. device technology development. Particular attention is devoted to time evolution of neutron multiplication factor since delayed development of the 233U buildup and so system reactivity are expected in the Th-U cycle. (3) Code E.A.s. device irradiation and post-irradiation modelling for determining higher actinides buildup, fission products formation and fuel consumption trends as function of time, system enrichment degree and flux level parameters. (4) The confirmation, on the basis of the same specific power irradiation, of expected actinides waste obtainment cleaner than the one deriving from the U-Pu cycle utilization. For this end, a model comparison of equivalent enriched fissile nuclides in both cycles has been devised as having, within the range of 0-700 days, ten irradiation periods of about 53 MW/ton specific power and equivalent cooling time post-irradiation periods.

  20. Simulation to enhance patient safety: why aren't we there yet?

    Science.gov (United States)

    Aggarwal, Rajesh; Darzi, Ara

    2011-10-01

    The delivery of state-of-the-art medical care is complex, with large numbers of treatment strategies often available to individual patients. It is paramount to ensure that each patient receives optimal treatment in a safe, effective, and timely manner. Evidence suggests that an unacceptably high number of patients currently experience suboptimal care as the result of adverse events and medical error. Simulation-based training reduces medical error, enhances clinical outcomes, and reduces the cost of clinical care. It is surprising that medical simulation is not routinely integrated into the training curricula of all health-care professionals. Simulation enables doctors to practice and hone their technical, communication, decision making, and crisis management skills in a safe and educationally orientated environment. The process can foster the development of interprofessional working skills, leading to enhanced patient outcomes. Selection, credentialing, and revalidation of medical professionals are also possible in a simulation setting, enabling maintenance of standards of practice throughout a medical career. In order for simulation to become a part of the medical curriculum, collaborative efforts are required from academics, physicians, managers, and policy makers alike. Bringing these groups together, while a challenge, can lead to high-level outputs in medical care, which will benefit all.

  1. Application of Peer-Assisted Learning in the safety education course of medical students%同伴互助学习在《大学生安全教育》课程中的应用

    Institute of Scientific and Technical Information of China (English)

    申正付; 齐玉龙; 冯丽丽; 陈晓彬

    2014-01-01

    Objective:To investigate the effects of Peer-Assisted Learning in the safety education course of medical students. Methods:Two hundred and six students from a clinical medical department of 2013 class A( the observation group) were divided into 20 Peer-assisted groups,who were taught using Peer-Assisted Learning method. Two hundred and one students from class B( the control group) were taught using the traditional lecturing method. The summative evaluation, teaching experience and satisfaction degree between two groups were compared. Results:The final summary evaluation scores of the observation group were significantly higher than that in control group(P<0. 01). The communication abilities,team cooperation abilities,learning efficiency,learning abilities,language expression abilities,experience to solve security problems and teaching satisfaction degree in observation group were higher than those in control group(P<0. 01). Conclusions:Peer-Assisted Learning can improve the medical students interest of learning safety education course and abilities to solve practical security problems,which can further enhance the teaching effects.%目的:探讨同伴互助学习在医学生安全教育课程中的应用效果。方法:把某医学院某系2013级A班206名本科医学生作为观察组,分为20个同伴互助小组,实施同伴互助学习的教学方法;B班201名医学生作为对照组,实施以讲授为主的传统教学方法。对2组医学生期末总结性评价成绩、问卷调查教学的体会和满意度结果进行比较。结果:观察组的期末总结性评价成绩显著高于对照组(P<0.01);观察组的交流能力、团队合作能力、学习效率、自学能力、语言表达能力、解决安全问题的能力和对教学的体会以及对教学满意度均明显高于对照组(P<0.01)。结论:同伴互助学习可以提升医学生学习《大学生安全教育》课程的兴趣,提高医学生解决实际安全问

  2. Plant designer's view of the operator's role in nuclear plant safety

    International Nuclear Information System (INIS)

    The nuclear plant operator's role supports the design assumptions and equipment with four functional tasks. He must set up th plant for predictable response to disturbances, operate the plant so as to minimize the likelihood and severity of event initiators, assist in accomplishing the safety functions, and feed back operating experiences to reinforce or redefine the safety analyses' assumptions. The latter role enhances the operator effectiveness in the former three roles. The Safety Level Concept offers a different perspective that enables the operator to view his roles in nuclear plant safety. This paper outlines the operator's role in nuclear safety and classifies his tasks using the Safety Level Concept

  3. Clinical effectiveness and safety of powered exoskeleton-assisted walking in patients with spinal cord injury: systematic review with meta-analysis

    Directory of Open Access Journals (Sweden)

    Miller LE

    2016-03-01

    Full Text Available Larry E Miller,1 Angela K Zimmermann,1 William G Herbert,1,2 1Miller Scientific Consulting, Inc., Asheville, NC, 2Department of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA, USA Background: Powered exoskeletons are designed to safely facilitate ambulation in patients with spinal cord injury (SCI. We conducted the first meta-analysis of the available published research on the clinical effectiveness and safety of powered exoskeletons in SCI patients. Methods: MEDLINE and EMBASE databases were searched for studies of powered exoskeleton-assisted walking in patients with SCI. Main outcomes were analyzed using fixed and random effects meta-analysis models. Results: A total of 14 studies (eight ReWalk™, three Ekso™, two Indego®, and one unspecified exoskeleton representing 111 patients were included in the analysis. Training programs were typically conducted three times per week, 60–120 minutes per session, for 1–24 weeks. Ten studies utilized flat indoor surfaces for training and four studies incorporated complex training, including walking outdoors, navigating obstacles, climbing and descending stairs, and performing activities of daily living. Following the exoskeleton training program, 76% of patients were able to ambulate with no physical assistance. The weighted mean distance for the 6-minute walk test was 98 m. The physiologic demand of powered exoskeleton-assisted walking was 3.3 metabolic equivalents and rating of perceived exertion was 10 on the Borg 6–20 scale, comparable to self-reported exertion of an able-bodied person walking at 3 miles per hour. Improvements in spasticity and bowel movement regularity were reported in 38% and 61% of patients, respectively. No serious adverse events occurred. The incidence of fall at any time during training was 4.4%, all occurring while tethered using a first-generation exoskeleton and none resulting in injury. The incidence of bone fracture during training was 3

  4. Microwave-assisted synthesis of BSA-protected small gold nanoclusters and their fluorescence-enhanced sensing of silver(i) ions

    Science.gov (United States)

    Yue, Yuan; Liu, Tian-Ying; Li, Hong-Wei; Liu, Zhongying; Wu, Yuqing

    2012-03-01

    A one-step microwave-assisted method is used for the synthesis of small gold nanoclusters, Au16NCs@BSA, which are used as a fluorescence enhanced sensor for detection of silver(i) ions with high selectivity and sensitivity.A one-step microwave-assisted method is used for the synthesis of small gold nanoclusters, Au16NCs@BSA, which are used as a fluorescence enhanced sensor for detection of silver(i) ions with high selectivity and sensitivity. Electronic supplementary information (ESI) available: Experimental details of the synthesis of AuNCs@BSA and fluorescent detection, and Fig. S1-S10. See DOI: 10.1039/c2nr12056a

  5. Quality Computer Assisted Mobile Learning (CAML) and Distance Education Leadership in Managing Technology Enhanced Learning Management System (TELMS) in the Malaysian Public Tertiary Education

    OpenAIRE

    Lee Tan Luck

    2009-01-01

    Abstract - The success in the implementation of a quality computer assisted mobile learning and distance education in a Technology Enhanced Learning Management System is highly rely on the academic leadership in managing and application of Information and Communication Technology (ICT) in the tertiary level. The effectiveness of its leadership, knowledge, application and management of ICT and learning management system is of utmost important. Successful application and management includes qua...

  6. Deterministic Safety Analysis for Nuclear Power Plants. Specific Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and I continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the contracting parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  7. Evaluation of Seismic Safety for Existing Nuclear Installations. Safety Guide (Russian Edition)

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and I continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the contracting parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  8. Safety Assessment for the Decommissioning of Facilities Using Radioactive Material. Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and I continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the Contracting Parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  9. Ultrasound assisted enhancement in natural dye extraction from beetroot for industrial applications and natural dyeing of leather.

    Science.gov (United States)

    Sivakumar, Venkatasubramanian; Anna, J Lakshmi; Vijayeeswarri, J; Swaminathan, G

    2009-08-01

    There is a growing demand for eco-friendly/non-toxic colorants, specifically for health sensitive applications such as coloration of food and dyeing of child textile/leather garments. Recently, dyes derived from natural sources for these applications have emerged as an important alternative to potentially harmful synthetic dyes and pose need for suitable effective extraction methodologies. The present paper focus on the influence of process parameters for ultrasound assisted leaching of coloring matter from plant materials. In the present work, extraction of natural dye from beetroot using ultrasound has been studied and compared with static/magnetic stirring as a control process at 45 degrees C. The influence of process parameters on the extraction efficiency such as ultrasonic output power, time, pulse mode, effect of solvent system and amount of beetroot has been studied. The use of ultrasound is found to have significant improvement in the extraction efficiency of colorant obtained from beetroot. Based on the experiments it has been found that a mixture of 1:1 ethanol-water with 80W ultrasonic power for 3h contact time provided better yield and extraction efficiency. Pulse mode operation may be useful in reducing electrical energy consumption in the extraction process. The effect of the amount of beetroot used in relation to extraction efficiency has also been studied. Two-stage extraction has been studied and found to be beneficial for improving the yield for higher amounts of beetroot. Significant 8% enhancement in % yield of colorant has been achieved with ultrasound, 80W as compared to MS process both using 1:1 ethanol-water. The coloring ability of extracted beet dye has been tested on substrates such as leather and paper and found to be suitable for dyeing. Ultrasound is also found to be beneficial in natural dyeing of leather with improved rate of exhaustion. Both the dyed substrates have better color values for ultrasonic beet extract as inferred from

  10. Accuracy and safety of intraoperative CT-assisted placement of pedicle screw%术中CT辅助下椎弓根螺钉置入的精确性和安全性评估

    Institute of Scientific and Technical Information of China (English)

    潘冬生; 宋振全; 赵明光; 张海松; 陆宇; 金振野

    2016-01-01

    Objective To assess the safety and accuracy of intraoperative CT assisted-placement of pedicle screw in the patients with spinal disorders. Methods The clinical data of 39 patients with spinal disorders, who underwent intraoperative CT-assisted placement of pedicle screws in our hospital from May, 2014 through May, 2015, were analyzed retrospectively. The accuracy of pedicle screw placement was assessed by Gertzbein-Robbins classification after the surgery. The safety of pedicle screw fixation was assessed by the postoperative complications. Results A total of 112 pedicle screws were placed in the spines in 39 patients and the placements of 38 screws of them were adjusted according to intraoperative CT findings. Of 112 screws, 105 were placed in the pedicles, 5 by grade 1 pedicle breach, and 2 by grad 2 pedicle breach according to Gertzbein-Robbins classification of pedicle screw placement accuracy. Two screws breached the medical pedicle walls, 4 breached the lateral walls and 1 breached inferolateral pedicle wall. The postoperative complications included surgical site infections in 4 patients, cerebrospinal fluid leaks in 2 and injury to the nerve in 1. No complication was directly related to the screws placement. No patient required reoperation due to the misplacement of the pedicle screws. Conclusions The accuracy and safety of pedicle screw placement can be enhanced in the patients with spinal disorders by intraoperative CT scanning which may be help the surgeon adjust the improper pedicle screw placement in time.%目的 评估术中CT辅助下椎弓根固定技术的安全性和准确性.方法 回顾性分析2014年5月至2015年5月术中CT辅助下椎弓根固定手术治疗的39例脊柱脊髓疾病患者的临床资料,其中脊柱脊髓损伤6例,颅颈交界区畸形6例,脊柱退行性变14例,脊柱脊髓肿瘤13例;术后应用Gertzbein-Robbins分级评价螺钉植入的精确性.结果 椎弓根螺钉固定总数为112枚,术中根据CT影像

  11. Microstructure study of alloy to enhance safety and reduce adverse environmental effects of future fusion power plants

    Energy Technology Data Exchange (ETDEWEB)

    Ghoranneviss, M.; Salar Elahi, A., E-mail: Salari_phy@yahoo.com

    2015-05-15

    Highlights: • Nano-metric precipitates through heat treatments in Cr–W–V alloy were formed. • Metallography studies shows that the microstructure of alloy has been tempered martensite. • The formation of nano-scale precipitates was confirmed by SEM observations. - Abstract: Reduced-activation steels were developed to enhance safety and reduce adverse environmental effects of future fusion power plants. Martensitic and bainitic steels were developed during the 1985–90 timeframe, and the feasibility of their use for fusion was investigated in an international collaboration from 1994 to present. This work continues to improve the steels and the formation of very small nano-metric precipitates through standardized heat treatments in Cr–W–V alloy system using the microscopic observations. Metallography studies have revealed that the microstructure of alloy after tempering has been tempered martensite. Also after tempering, the matrix structure of alloy and the formation of nano-scale precipitates on grain and lath boundaries were confirmed by SEM observations. By the application of XRD spectra analysis and TEM electron diffraction patterns, it was shown that the type of precipitates extracted from alloy, would be M{sub 23}C{sub 6} and M{sub 7}C{sub 3}that include a cubic and trigonal crystal structure, respectively.

  12. Performance Improvement of Microcrystalline p-SiC/i-Si/n-Si Thin Film Solar Cells by Using Laser-Assisted Plasma Enhanced Chemical Vapor Deposition

    Directory of Open Access Journals (Sweden)

    Hsin-Ying Lee

    2014-01-01

    Full Text Available The microcrystalline p-SiC/i-Si/n-Si thin film solar cells treated with hydrogen plasma were fabricated at low temperature using a CO2 laser-assisted plasma enhanced chemical vapor deposition (LAPECVD system. According to the micro-Raman results, the i-Si films shifted from 482 cm−1 to 512 cm−1 as the assisting laser power increased from 0 W to 80 W, which indicated a gradual transformation from amorphous to crystalline Si. From X-ray diffraction (XRD results, the microcrystalline i-Si films with (111, (220, and (311 diffraction were obtained. Compared with the Si-based thin film solar cells deposited without laser assistance, the short-circuit current density and the power conversion efficiency of the solar cells with assisting laser power of 80 W were improved from 14.38 mA/cm2 to 18.16 mA/cm2 and from 6.89% to 8.58%, respectively.

  13. Pacific Northwest Laboratory annual report for 1985 to the DOE Office of the Assistant Secretary for Environment, Safety and Health. Part 5. Overview and assessment

    International Nuclear Information System (INIS)

    This volume is progress on work performed for the Office of Nuclear Safety, the Office of Operational Safety, and for the Office of Environmental Analysis for each project. Separate abstracts have been prepared for individual projects. ACR

  14. Pacific Northwest Laboratory annual report for 1985 to the DOE Office of the Assistant Secretary for Environment, Safety and Health. Part 5. Overview and assessment

    Energy Technology Data Exchange (ETDEWEB)

    Faust, L.G.

    1986-02-01

    This volume is progress on work performed for the Office of Nuclear Safety, the Office of Operational Safety, and for the Office of Environmental Analysis for each project. Separate abstracts have been prepared for individual projects. ACR

  15. Maritime transport safety enhancement

    International Nuclear Information System (INIS)

    As the density of sea traffic keeps growing, designing ship structures capable of withstanding accidental loads such as collisions or grounding without detrimental consequences proves an ever-greater challenge. Double hull designs play a major role in this respect, as explains Manolis Samuelides, Professor at the National Technical University of Athens. (orig.)

  16. Maritime transport safety enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Samuelides, Manolis [National Technical University of Athens (Greece); University School of Naval Architecture and Marine Engineering, Zografos (Greece). Div. for Marine Structures

    2013-11-15

    As the density of sea traffic keeps growing, designing ship structures capable of withstanding accidental loads such as collisions or grounding without detrimental consequences proves an ever-greater challenge. Double hull designs play a major role in this respect, as explains Manolis Samuelides, Professor at the National Technical University of Athens. (orig.)

  17. Opening Address [International Conference on Effective Nuclear Regulatory Systems: Further Enhancing the Global Nuclear Safety and Security Regime, Cape Town (South Africa), 14-18 December 2009

    International Nuclear Information System (INIS)

    meet the world's needs for human well-being, growth and development. The IAEA continues to support and promote continuous improvements in the global nuclear safety and security regime as a framework for achieving high levels of safety and security in nuclear activities worldwide and to overcome the inertia of the levelling off of performance. Examples of continuous improvements in this sense include the development of more comprehensive and user friendly safety guides, better safety and security performance indicators, more useful analytical tools for evaluation of regulatory performance, enhanced self-assessment and peer review mechanisms, and more sharing of experience and lessons learned

  18. Microwave-assisted in situ synthesis of reduced graphene oxide-BiVO{sub 4} composite photocatalysts and their enhanced photocatalytic performance for the degradation of ciprofloxacin

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Yan [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013 (China); Sun, Shaofang [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013 (China); School of Environmental Science and Engineering, Chang’an University, Yanta Road 126, Xi’an, 710054 (China); Song, Yang; Yan, Xu [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013 (China); Guan, Weisheng [School of Environmental Science and Engineering, Chang’an University, Yanta Road 126, Xi’an, 710054 (China); Liu, Xinlin [School of Material Science and Engineering, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013 (China); Shi, Weidong, E-mail: swd1978@ujs.edu.cn [School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Road 301, Zhenjiang, 212013 (China)

    2013-04-15

    Highlights: ► Microwave-assisted in situ growth of RGO-BiVO{sub 4} composite was proposed. ► A relatively small particle size with organic-additives free. ► Graphene was formed during the microwave-heating by oxygen capture. ► GB-2 sample exhibits the highest CIP degradation ratio (3 times over pure BiVO{sub 4}). ► The enhancements of activities result from the effective charge separation. -- Abstract: To improve the photodegradation efficiency for ciprofloxacin (CIP), a new-type microwave-assisted in situ growth method is developed for the preparation of reduced graphene oxide (RGO) -BiVO{sub 4} composite photocatalysts. The as-produced RGO-BiVO{sub 4} composite photocatalysts show extremely high enhancement of CIP degradation ratio over the pure BiVO{sub 4} photocatalyst under visible light. Specially, the 2 wt% RGO-BiVO{sub 4} composite photocatalyst exhibits the highest CIP degradation ratio (68.2%) in 60 min, which is over 3 times than that (22.7%) of the pure BiVO{sub 4} particles. The enhancement of photocatalytic activities of RGO-BiVO{sub 4} photocatalysts can be attributed to the effective separation of electron–hole pairs rather than the improvement of light absorption.

  19. Microwave-assisted in situ synthesis of reduced graphene oxide-BiVO4 composite photocatalysts and their enhanced photocatalytic performance for the degradation of ciprofloxacin

    International Nuclear Information System (INIS)

    Highlights: ► Microwave-assisted in situ growth of RGO-BiVO4 composite was proposed. ► A relatively small particle size with organic-additives free. ► Graphene was formed during the microwave-heating by oxygen capture. ► GB-2 sample exhibits the highest CIP degradation ratio (3 times over pure BiVO4). ► The enhancements of activities result from the effective charge separation. -- Abstract: To improve the photodegradation efficiency for ciprofloxacin (CIP), a new-type microwave-assisted in situ growth method is developed for the preparation of reduced graphene oxide (RGO) -BiVO4 composite photocatalysts. The as-produced RGO-BiVO4 composite photocatalysts show extremely high enhancement of CIP degradation ratio over the pure BiVO4 photocatalyst under visible light. Specially, the 2 wt% RGO-BiVO4 composite photocatalyst exhibits the highest CIP degradation ratio (68.2%) in 60 min, which is over 3 times than that (22.7%) of the pure BiVO4 particles. The enhancement of photocatalytic activities of RGO-BiVO4 photocatalysts can be attributed to the effective separation of electron–hole pairs rather than the improvement of light absorption

  20. Dilemmas in providing resilience-enhancing social services to long-term social assistance clients. A qualitative study of Swedish social workers

    Directory of Open Access Journals (Sweden)

    Marttila Anneli

    2012-07-01

    Full Text Available Abstract Background Long-term recipients of social assistance face barriers to social and economic inclusion, and have poorer health and more limited opportunities for improving their health than many other groups in the population. During recent decades there have been changes in Swedish social policy, with cutbacks in public benefits and a re-emphasis on means-tested policies. In this context, it is important to investigate the necessary conditions for social workers to offer social assistance and services, as well as the mediating role of social workers between public policies and their clients. Swedish social services aim to promote social inclusion by strengthening the individual´s own resources. We investigated the issues that arise when providing social services to long-term social assistance clients within the framework of resilience, which focuses on the processes leading to positive functioning in adverse conditions. Methods Interviews were conducted with 23 social workers in Stockholm and analysed by qualitative content analysis. Results The main theme to emerge from the interviews concerned the constraints that the social workers faced in providing social services to social assistance clients. The first subtheme focused on dilemmas in the interaction between social workers and clients resulting from the dual role of exercising authority and supporting and building trust with clients. Working conditions of social workers also played a crucial role. The second subtheme addressed the impact of the societal context, such as labour market opportunities and coordination between authorities. Conclusions Overall, we found that social workers to a great extent tried to find individual solutions to structural problems. To provide resilience-enhancing social services to long-term social assistance clients with varying obstacles and needs requires a constructive working environment, supportive societal structures and inter-sectoral cooperation

  1. Nuclear safety cooperation for Soviet designed reactors

    International Nuclear Information System (INIS)

    The nuclear accident at the Chernobyl nuclear power plant in 1986 first alerted the West to the significant safety risks of Soviet designed reactors. Five years later, this concern was reaffirmed when the IAEA, as a result of a review by an international team of nuclear safety experts, announced that it did not believe the Kozloduy nuclear power plants in Bulgaria could be operated safely. To address these safety concerns, the G-7 summit in Munich in July 1992 outlined a five point program to address the safety problems of Soviet Designed Reactors: operational safety improvement; near-term technical improvements to plants based on safety assessment; enhancing regulatory regimes; examination of the scope for replacing less safe plants by the development of alternative energy sources and the more efficient use of energy; and upgrading of the plants of more recent design. As of early 1994, over 20 countries and international organizations have pledged hundreds of millions of dollars in financial assistance to improve safety. This paper summarizes these assistance efforts for Soviet designed reactors, draws lessons learned from these activities, and offers some options for better addressing these concerns

  2. Investigating Chinese Vegetable Processing Firms’ Economic Incentives to Enhance Quality and Safety Controls

    OpenAIRE

    Zhou, Jiehong; Yue, Chengyan

    2010-01-01

    China’s vegetable quality and safety controls are being challenged as previously seen in other food industries. This study surveyed 170 vegetable processing firms in Zhejiang, China. We systematically investigated Chinese vegetable processing firms’ current status of quality and safety controls and factors affecting firms’ propensity to invest in food safety controls in the future. This study shows that a processing firm's incentive for food safety and quality control comes directly fro...

  3. IAEA Sub-Programme on Research Reactor Safety

    International Nuclear Information System (INIS)

    The IAEA has greatly contributed through its programmes and activities to the records of safe operation of research reactors worldwide. Since 2006, the activities of the IAEA sub-programme on research reactor safety have been mainly focusing on supporting Member States (MSs) to enhance the safety of their research reactors mainly through the application of the Code of Conduct on the Safety of Research Reactors for the management of the safety of these facilities. In doing so, the key part of the implementation strategy of the activities included the development of Safety Standards and supporting documents. At present, the corpus of Safety Standards for research reactors has reached maturity. Safety review services, based on the IAEA Safety Standards, were provided, in the field, through the implementation of Integrated Safety Assessment (INSARR) missions and other safety review and expert missions. Since 2006, about one hundred missions were conducted to research reactors worldwide. Fact finding missions were also implemented by the IAEA in MSs establishing their first research reactors in order to identify gaps and define actions to assist them building the necessary technical and safety infrastructures. An important part of the implementation strategy for the IAEA safety enhancement plan included the fostering of regional and international cooperation to enhance operational safety and regulatory supervision of research reactors, and support for the establishment and functioning of regional advisory safety committees and nuclear safety networks. International exchange of information and sharing of operating experience feedback are essential contributors for enhancing safety and have been promoted through the IAEA web-based incident reporting system for research reactors IRSRR which ensures the collection of data and information on events and the dissemination of lessons learned from their analysis. Existing inconsistencies in the safety demonstrations for research

  4. Robot-assisted and computer-enhanced therapies for children with cerebral palsy: current state and clinical implementation.

    Science.gov (United States)

    Meyer-Heim, Andreas; van Hedel, Hubertus J A

    2013-06-01

    The field of pediatric neurorehabilitation has rapidly evolved with the introduction of technological advancements over recent years. Rehabilitation robotics and computer-assisted systems can complement conventional physiotherapeutics or occupational therapies. These systems appear promising, especially in children, where exciting and challenging virtual reality scenarios could increase motivation to train intensely in a playful therapeutic environment. Despite promising experience and a large acceptance by the patients and parents, so far, only a few therapy systems have been evaluated in children, and well-designed randomized controlled studies in this field are still lacking. This narrative review aims to provide an overview about the to-date robot-assisted and computer-based therapies and the current level of evidence and to share the authors experience about the clinical implication of these new technologies available for children with cerebral palsy. PMID:23948688

  5. Enhancing prospective chemistry teachers cognitive structures in the topics of bonding and hybridization by internet-assisted chemistry applications

    Directory of Open Access Journals (Sweden)

    Özge Özyalçın Oskay, Sinem Dinçol

    2011-08-01

    Full Text Available The purpose of this study is to determine the effects of internet-assisted chemistry applications on prospective chemistry teachers’ cognitive structures in the topics of bonding and hybridization. The sample of the study consisted of 36 prospective chemistry teachers attending Hacettepe University, Faculty of Education, the Department of Chemistry Education in 2010-2011 academic year and taking Basic Chemistry I lesson. In the study, students were separated into experimental and control groups according to their pre-cognitive structures. Students were requested to answer two open ended questions. Answers by each student were gathered and evaluated by flow map method. “Bonding and hybridization” topics were taught to control group with traditional teaching method and to experimental group besides traditional method internet-assisted applications were conducted. The same open-ended questions were given to both groups and their cognitive structures were examined once more. The differences between control and experimental groups’ cognitive structures were examined. A significant difference was identified in favour of experimental group (p<0, 05. The mean score of the Experimental group was X=19.94, and the mean score of the Control group was X=13.88. In addition, subsequent to internet assisted chemistry applications differences in terms of concepts and descriptions in prospective chemistry teachers’ in experimental and control group cognitive structure have been determined. When post flow maps of prospective chemistry teachers in experimental group, on whom internet assisted chemistry applications were made, are formed, it has been determined that there are more statements about hybridization, hybridization types, molecule geometry and bond angles compared to control grou

  6. Enhanced Etching, Surface Damage Recovery, and Submicron Patterning of Hybrid Perovskites using a Chemically Gas-Assisted Focused-Ion Beam for Subwavelength Grating Photonic Applications.

    Science.gov (United States)

    Alias, Mohd S; Yang, Yang; Ng, Tien K; Dursun, Ibrahim; Shi, Dong; Saidaminov, Makhsud I; Priante, Davide; Bakr, Osman M; Ooi, Boon S

    2016-01-01

    The high optical gain and absorption of organic-inorganic hybrid perovskites have attracted attention for photonic device applications. However, owing to the sensitivity of organic moieties to solvents and temperature, device processing is challenging, particularly for patterning. Here, we report the direct patterning of perovskites using chemically gas-assisted focused-ion beam (GAFIB) etching with XeF2 and I2 precursors. We demonstrate etching enhancement in addition to controllability and marginal surface damage compared to focused-ion beam (FIB) etching without precursors. Utilizing the GAFIB etching, we fabricated a uniform and periodic submicron perovskite subwavelength grating (SWG) absorber with broadband absorption and nanoscale precision. Our results demonstrate the use of FIB as a submicron patterning tool and a means of providing surface treatment (after FIB patterning to minimize optical loss) for perovskite photonic nanostructures. The SWG absorber can be patterned on perovskite solar cells to enhance the device efficiency through increasing light trapping and absorption.

  7. Enhanced Etching, Surface Damage Recovery, and Submicron Patterning of Hybrid Perovskites using a Chemically Gas-Assisted Focused-Ion Beam for Subwavelength Grating Photonic Applications

    KAUST Repository

    Alias, Mohd Sharizal Bin

    2015-12-22

    The high optical gain and absorption of organic–inorganic hybrid perovskites have attracted attention for photonic device applications. However, owing to the sensitivity of organic moieties to solvents and temperature, device processing is challenging, particularly for patterning. Here, we report the direct patterning of perovskites using chemically gas-assisted focused-ion beam (GAFIB) etching with XeF2 and I2 precursors. We demonstrate etching enhancement in addition to controllability and marginal surface damage compared to focused-ion beam (FIB) etching without precursors. Utilizing the GAFIB etching, we fabricated a uniform and periodic submicron perovskite subwavelength grating (SWG) absorber with broadband absorption and nanoscale precision. Our results demonstrate the use of FIB as a submicron patterning tool and a means of providing surface treatment (after FIB patterning to minimize optical loss) for perovskite photonic nanostructures. The SWG absorber can be patterned on perovskite solar cells to enhance the device efficiency through increasing light trapping and absorption.

  8. Safety and Efficacy of Gadoxetate Disodium–Enhanced Liver MRI in Pediatric Patients Aged >2 Months to <18 Years—Results of a Retrospective, Multicenter Study

    Science.gov (United States)

    Geller, James; Kasahara, Mureo; Martinez, Mercedes; Soresina, Annarosa; Kashanian, Fran; Endrikat, Jan

    2016-01-01

    PURPOSE To assess the safety and efficacy of gadoxetate disodium–enhanced liver MR imaging in pediatric patients. MATERIAL AND METHODS Retrospective, multicenter study including pediatric patients aged >2 months to <18 years who underwent contrast-enhanced liver MRI due to focal liver lesions. A single intravenous bolus injection of 0.025 to 0.05 mmol/kg body weight of gadoxetate disodium was administered. Adverse events (AEs) up to 24 hours after injection were recorded and a one-year follow-up was conducted for all serious and unexpected AEs. Efficacy was defined based on the additional diagnostic information obtained from the combined (pre- and postcontrast) image sets as compared with the precontrast image sets by blinded reading. RESULTS A total of 52 patients for safety and 51 patients for efficacy analyses were evaluated. Twenty-two patients (42.3%) reported a total of 51 serious AEs (SAEs) and one AE after one year. No SAE or AE was related to gadoxetate disodium injection. Gadoxetate disodium–related effects on vital signs were not seen. Additional diagnostic information was obtained for 86.3% of patients. The three most improved efficacy variables were lesion-to-background contrast, lesion characterization, and improved border delineation in 78.4%, 76.5%, and 70.6% of patients, respectively. CONCLUSION Gadoxetate disodium in pediatric patients did not raise any clinically significant safety concern. Contrast enhancement provided additional clinically relevant information. PMID:27478381

  9. Ultra-thin titanium nanolayers for plasmon-assisted enhancement of bioluminescence of chloroplast in biological light emitting devices

    Energy Technology Data Exchange (ETDEWEB)

    Hsun Su, Yen [Department of Materials Science and Engineering, National Cheng Kung University, Tainan 70101, Taiwan (China); Advanced Optoelectronic Technology Center, National Cheng Kung University, Tainan 70101, Taiwan (China); Hsu, Chia-Yun; Chang, Chung-Chien [Science and Technology of Accelerator Light Source, Hsinchu 300, Taiwan (China); Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu 300, Taiwan (China); Tu, Sheng-Lung; Shen, Yun-Hwei [Department of Resource Engineering, National Cheng Kung University, Tainan 70101, Taiwan (China)

    2013-08-05

    Ultra-thin titanium films were deposited via ultra-high vacuum ion beam sputter deposition. Since the asymmetric electric field of the metal foil plane matches the B-band absorption of chlorophyll a, the ultra-thin titanium nanolayers were able to generate surface plasmon resonance, thus enhancing the photoluminescence of chlorophyll a. Because the density of the states of plasmon resonance increases, the enhancement of photoluminescence also rises. Due to the biocompatibility and inexpensiveness of titanium, it can be utilized to enhance the bioluminescence of chloroplast in biological light emitting devices, bio-laser, and biophotonics.

  10. Ultra-thin titanium nanolayers for plasmon-assisted enhancement of bioluminescence of chloroplast in biological light emitting devices

    International Nuclear Information System (INIS)

    Ultra-thin titanium films were deposited via ultra-high vacuum ion beam sputter deposition. Since the asymmetric electric field of the metal foil plane matches the B-band absorption of chlorophyll a, the ultra-thin titanium nanolayers were able to generate surface plasmon resonance, thus enhancing the photoluminescence of chlorophyll a. Because the density of the states of plasmon resonance increases, the enhancement of photoluminescence also rises. Due to the biocompatibility and inexpensiveness of titanium, it can be utilized to enhance the bioluminescence of chloroplast in biological light emitting devices, bio-laser, and biophotonics

  11. Yb,Er-doped CeO2 nanotubes as an assistant layer for photoconversion-enhanced dye-sensitized solar cells

    Science.gov (United States)

    Zhao, Rongfang; Huan, Long; Gu, Peng; Guo, Rong; Chen, Ming; Diao, Guowang

    2016-11-01

    Yb,Er-doped CeO2 nanotubes were successfully synthesized using Ag nanowires as a hard template via a facile hydrothermal reaction and subsequent calcination and leaching processes. Yb,Er-doped CeO2 nanotubes as a promising assistant layer were investigated to determine theirs photovoltaic properties in an effort to enhance the power conversion efficiency of dye-sensitized solar cells (DSSCs). The influence factors of photoelectric properties of CeO2:Yb,Er NTs, including diameter of nanotubes, hydrothermal time, calcination temperature, and elements doping, have been studied. Compared with pristine P25 photoanode, the DSSCs fabricated by CeO2:Yb,Er nanotubes and P25 exhibited a power conversion efficiency (η) of 8.67%, an increase of 34%, and incident photo-to-electric conversion efficiency (IPCE) of 92.96%, an increase of 48.83%, which evidence that CeO2:Yb,Er NTs are a promising assistant photoanode material for DSSCs. The enhance mechanism of CeO2:Yb,Er nanotubes has been further revealed according to experimental results.

  12. Quantum sized Ag nanocluster assisted fluorescence enhancement in Tm3+-Yb3+ doped optical fiber beyond plasmonics

    International Nuclear Information System (INIS)

    We report a process for enhancing fluorescence emission from conventional rare earth ions in optical fiber by metal nanocluster (MNC) in nonresonant indirect pumping. The process is completely different from formal metal enhanced fluorescence phenomenon as the MNCs are too small in size to support localized surface plasmon and the excitation wavelength is far from plasmon resonance frequency. We used an established theory of two coupled oscillators to explain the simultaneous enhancement of Ytterbium (Yb3+) and Thulium (Tm3+) emission by silver (Ag) NCs under nonresonant pumping in optical fiber. The fiber is pumped with a 980 nm fiber pigtailed laser diode with input power of 20–100 mW to excite the Yb3+. Four times enhancement of Yb3+ emission of 900–1100 nm and Tm3+ upconversion emission around 474 nm, 650 nm, and 790 nm is observed in the fiber with Ag NCs

  13. Hollow nanoporous covalent triazine frameworks via acid vapor-assisted solid phase synthesis for enhanced visible light photoactivity

    KAUST Repository

    Huang, Wei

    2016-04-11

    Herein, we report a novel trifluoromethanesulfonic acid vapor-assisted solid phase synthetic method to construct nanoporous covalent triazine frameworks with highly ordered hollow interconnected pores under mild reaction conditions. This unique solid state synthetic route allows not only the avoidance of undesired side reactions caused by traditional high temperature synthesis, but also the maintaining of defined and precise optical and electronic properties of the nonporous triazine frameworks. Promising photocatalytic activity of the polytriazine networks was demonstrated in the photoreduction reaction of 4-nitrophenol into 4-aminophenol under visible light irradiation.

  14. A study on activities of nuclear stations in the U.S. in the aim of enhancing safety culture

    International Nuclear Information System (INIS)

    After the discovery of a Reactor Vessel Head Degradation at Davis Besse, the NRC, a regulatory body in the U.S., launched an evaluation scheme regarding nuclear stations' Safety Culture. In this evaluation, the NRC examines every inspection finding of conventional Reactor Oversight Program inspections to find out what was the most dominant causal factor with SC aspects. There are no similar analyses of this kind opened to public. This study has its goal of obtaining some useful clue for realizing how to project SC enhancement activities, by making analysis on every ROP inspection finding as well as collecting examples of good practices in improving organizational performance of stations in the U.S. As for the inspection results of ROP, there are no obvious change in the trend of number and types of ROP findings. On the other hand, because of the variety in average number of findings at stations, we could assume that actual condition of SC within a particular station quite differs from other stations. Looking at ROP reports minutely, you may realize that all U.S. stations have been making great effort to improve the efficiency of its Corrective Action Program which is regarded as the key ability to identify and fix undesirable incidents broke out at the station. It is a noteworthy aspect that CAP is not a simple program of quality assurance but also one of the items in power stations to be improved continuously. The concrete elements of this process are realizing current organizational condition by series of Performance Indicators, setting the next goals with the PIs, also evaluating the degree of the achievements with them, and modifying or re-defining new goal of the organization in accordance with new situation. This idea is introduced into broad range of organizational activities all over the U.S., which assure their improvement to be objective and effective. Simultaneously, such way of operation have its staff devoted in own responsibility, which eventually

  15. The development of a total quality indicator for the assessment of travel demand management measures: focus on road safety policy

    OpenAIRE

    Tormans, Hans; Janssens, Davy; Brijs, Tom; Wets, Geert

    2008-01-01

    In this paper, we discuss the conceptual idea of the development of an instrument that assists local authorities in enhancing their traffic safety policy. Taking the principles of Total Quality Management into account, we build up a tool which positions local road safety policy on a ladder of development. To define which rung the administration has reached so far, we consider both organizational and operational aspects of road safety policy making. Questionnaires have been set up to gain insi...

  16. Gadobutrol for contrast-enhanced magnetic resonance imaging in elderly patients: review of the safety profile from clinical trial, post-marketing surveillance, and pharmacovigilance data

    International Nuclear Information System (INIS)

    Aim: To assess the safety of gadobutrol administration in elderly patients (≥65 years) by comparing the incidence of adverse drug reactions (ADRs) following gadobutrol-enhanced magnetic resonance imaging (MRI) procedures in elderly patients with that in adults aged 18–64 years. Materials and methods: Safety data on gadobutrol administration from clinical trials, post-marketing surveillance (PMS) studies, and pharmacovigilance reports were collected in three databases. In each dataset, absolute and relative frequencies of ADRs between age groups were analysed, along with odds ratios and 95% confidence intervals. Logistic regression was used to identify significant influencing factors on ADRs in the PMS and pharmacovigilance data. Results: Rates of reported ADRs were lower in elderly patients versus adults aged <65 years due to a reduced incidence of non-serious ADRs; this was statistically significant for the clinical trials and pharmacovigilance populations, with a trend in the PMS database. Serious ADRs occurred infrequently in the clinical trials and PMS populations (too low for statistical comparison), and pharmacovigilance data demonstrated a low incidence (<0.005%) in both age groups. Conclusions: This evaluation involving three large databases demonstrated no greater incidence of ADRs following gadobutrol-enhanced MRI in elderly patients (≥65 years) compared with younger adults, with gadobutrol having a favourable safety profile in both age groups. -- Highlights: •First dedicated safety study of an extracellular contrast agent in the elderly. •Elderly patients experience fewer non-serious ADRs than younger adults. •Gadobutrol has a favourable safety profile in both age groups

  17. 从“壬基酚”事件看我国纺织印染助剂的安全性问题%Safety problem of China's textile and dyeing assistants from nonylphenol event

    Institute of Scientific and Technical Information of China (English)

    章杰

    2012-01-01

    最近“壬基酚”事件在我国纺织行业和助剂行业引起了强烈反响,从源头上寻找问题的症结对保障纺织品的安全性至关重要.阐述了当今我国纺织印染助剂的安全性问题,分析了问题产生的原因以及禁用或限用纺织印染助剂的替代品中存在的问题,指出助剂行业必须跟上市场的发展新趋势和法律新约束,加紧开发替代品,切实生产出环保型助剂、绿色助剂、安全助剂、放心助剂,更好地为纺织行业服务.%Recently "nonylphenol" event in China's textile and assistant industry has aroused strong repercussions. Searching for the sticking point from the source of the problem is very important for the textile security. The safety problem of china's textile and dyeing assistants was elaborated. The reason of the problem and the problems of substitute of restricted or banned textile assistants were analyzed. It was pointed out that auxiliary industry must keep pace with the new development trend of market and legal constraints, accelerate the development of substitutes, produce environmental friendly assistants, green assistants, safe and secure assistants, and better serve the textile industry.

  18. Mo-O bond doping and related-defect assisted enhancement of photoluminescence in monolayer MoS2

    Directory of Open Access Journals (Sweden)

    Xiaoxu Wei

    2014-12-01

    Full Text Available In this work, we report a strong photoluminescence (PL enhancement of monolayer MoS2 under different treatments. We find that by simple ambient annealing treatment in the range of 200 °C to 400 °C, the PL emission can be greatly enhanced by a factor up to two orders of magnitude. This enhancement can be attributed to two factors: first, the formation of Mo-O bonds during ambient exposure introduces an effective p-doping in the MoS2 layer; second, localized electrons formed around Mo-O bonds related defective sites where the electrons can be effectively localized with higher binding energy resulting in efficient radiative excitons recombination. Time resolved PL decay measurement showed that longer lifetime of the treated sample consistent with the higher quantum efficiency in PL. These results give more insights to understand the luminescence properties of the MoS2.

  19. Summary and conclusions of the conference [International conference on challenges faced by technical and scientific support organizations in enhancing nuclear safety

    International Nuclear Information System (INIS)

    . Technical and scientific support organizations (TSOs), whether part of a regulatory body or a separate organization, are gaining increased importance in providing the technical and scientific bases for decisions and activities regarding nuclear and radiation safety. International organizations such as the IAEA and the OECD Nuclear Energy Agency (OECD/NEA) also rely on the active contribution of TSOs. In the light of the important role played by TSOs, it is essential that these organizations conduct their work consistent with the highest levels of technical competence and transparency, and with the observance of ethical principles. To enhance their capabilities in these areas, TSOs need to foster cooperative activities among themselves and other relevant organizations, whether on an ad hoc basis or in the framework of regional or multilateral arrangements and institutions. Recognizing the need for TSOs to broaden their cooperation, the IAEA has sponsored this first international conference specifically addressing the role TSOs can play and the challenges they face in enhancing nuclear safety. It is hoped that the conference provided a platform for further promoting and strengthening international nuclear and radiation safety cooperation to enhance the Global Nuclear Safety Regime

  20. Pacific Northwest Laboratory annual report for 1984 to the DOE Office of the Assistant Secretary for Policy, Safety, and Environment. Part 5. Overview and assessment

    International Nuclear Information System (INIS)

    Research conducted in 1984 is briefly described. Research areas include: (1) uncertainties in modeling source/receptor relations for acidic deposition; (2) health physics support and assistance to the DOE; (3) technical guidelines for radiological calibrations; (4) personnel neutron dosemeter evaluation and upgrade program; (5) beta measurement evaluation and upgrade; (6) accreditation program for occupational exposure measurements; (7) assurance program for Remedial Action; (8) environmental protection support and assistance; (9) hazardus waste risk assessment; and (10) radiation policy studies

  1. Pacific Northwest Laboratory annual report for 1981 to the DOE Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness. Part 5. Environmental and occupational protection, assessment, and engineering

    International Nuclear Information System (INIS)

    This report describes research in environment, health, and safety conducted during fiscal year 1981. The five parts of the report are oriented to particular segments of the program. Parts 1 to 4 report on research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. Part 5 reports progress on all research performed for the Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness. The parts are: Part 1: Biomedical Sciences under Program Manager, H. Drucker; Part 2: Ecological Sciences, under Program Manager, B.E. Vaughan; Part 3: Atmospheric Sciences under Program Manager, C.E. Elderkin; Part 4: Physical Sciences under Program Manager, J.M. Nielsen; and Part 5: Environmental and Occupational Protection, Assessment, and Engineering under Program Managers, D.L. Hessel, S. Marks, and W.A. Glass

  2. Pacific Northwest Laboratory annual report for 1981 to the DOE Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness. Part 5. Environmental and occupational protection, assessment, and engineering

    Energy Technology Data Exchange (ETDEWEB)

    Glass, W.A.

    1982-02-01

    This report describes research in environment, health, and safety conducted during fiscal year 1981. The five parts of the report are oriented to particular segments of the program. Parts 1 to 4 report on research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. Part 5 reports progress on all research performed for the Office of the Assistant Secretary for Environmental Protection, Safety and Emergency Preparedness. The parts are: Part 1: Biomedical Sciences under Program Manager, H. Drucker; Part 2: Ecological Sciences, under Program Manager, B.E. Vaughan; Part 3: Atmospheric Sciences under Program Manager, C.E. Elderkin; Part 4: Physical Sciences under Program Manager, J.M. Nielsen; and Part 5: Environmental and Occupational Protection, Assessment, and Engineering under Program Managers, D.L. Hessel, S. Marks, and W.A. Glass.

  3. The Enhanced Light Absorptance and Device Application of Nanostructured Black Silicon Fabricated by Metal-assisted Chemical Etching.

    Science.gov (United States)

    Zhong, Hao; Guo, Anran; Guo, Guohui; Li, Wei; Jiang, Yadong

    2016-12-01

    We use metal-assisted chemical etching (MCE) method to fabricate nanostructured black silicon on the surface of C-Si. The Si-PIN photoelectronic detector based on this type of black silicon shows excellent device performance with a responsivity of 0.57 A/W at 1060 nm. Silicon nanocone arrays can be created using MCE treatment. These modified surfaces show higher light absorptance in the near-infrared range (800 to 2500 nm) compared to that of C-Si with polished surfaces, and the variations in the absorption spectra of the nanostructured black silicon with different etching processes are obtained. The maximum light absorptance increases significantly up to 95 % in the wavelength range of 400 to 2500 nm. Our recent novel results clearly indicate that nanostructured black silicon made by MCE has potential application in near-infrared photoelectronic detectors. PMID:27368764

  4. Constant pressure-assisted head-column field-amplified sample injection in combination with in-capillary derivatization for enhancing the sensitivity of capillary electrophoresis.

    Science.gov (United States)

    Yan, Na; Zhou, Lei; Zhu, Zaifang; Zhang, Huige; Zhou, Ximin; Chen, Xingguo

    2009-05-15

    In this work, a novel method combining constant pressure-assisted head-column field-amplified sample injection (PA-HC-FASI) with in-capillary derivatization was developed for enhancing the sensitivity of capillary electrophoresis. PA-HC-FASI uses an appropriate positive pressure to counterbalance the electroosmotic flow in the capillary column during electrokinetic injection, while taking advantage of the field amplification in the sample matrix and the water of the "head column". Accordingly, the analytes were stacked at the stationary boundary between water and background electrolyte. After 600s PA-HC-FASI, 4-fluoro-7-nitro-2,1,3-benzoxadiazole as derivatization reagent was injected, followed by an electrokinetic step (5kV, 45s) to enhance the mixing efficiency of analytes and reagent plugs. Standing a specified time of 10min for derivatization reaction under 35 degrees C, then the capillary temperature was cooled to 25 degrees C and the derivatives were immediately separated and determined under 25 degrees C. By investigating the variables of the presented approach in detail, on-line preconcentration, derivatization and separation could be automatically operated in one run and required no modification of current CE commercial instrument. Moreover, the sensitivity enhancement factor of 520 and 800 together with the detection limits of 16.32 and 6.34pg/mL was achieved for model compounds: glufosinate and aminomethylphosphonic acid, demonstrating the high detection sensitivity of the presented method. PMID:19342058

  5. Nuclear safety in perspective

    OpenAIRE

    Andersson, K.; Sjöberg, B.M.D.; Lauridsen, Kurt; Wahlström, B.

    2003-01-01

    The aim of the NKS/SOS-1 project has been to enhance common understanding about requirements for nuclear safety by finding improved means of communicat-ing on the subject in society. The project, which has been built around a number of seminars, wassupported by limited research in three sub-projects: Risk assessment Safety analysis Strategies for safety management The report describes an industry in change due to societal factors. The concepts of risk and safety, safety management and systems...

  6. Sensor chip design for increasing surface-plasmon-assisted fluorescence enhancement of the V-trench biosensor

    Science.gov (United States)

    Ashiba, Hiroki; Fujimaki, Makoto; Wang, Xiaomin; Awazu, Koichi; Tamura, Takamasa; Shimizu, Yoshiyuki

    2016-06-01

    A sensor chip design for the V-trench biosensor, which is an instrument for highly sensitive fluorescence assay, was investigated to increase its sensitivity. A simulation based on the transfer matrix method revealed that the vertex angle and electric field enhancements of the V-trench biosensor chip are increased by employing a high-refractive-index material for the chip. It was proved that a chip made of high-refractive-index glass for press molding exhibited a 1.4-fold larger electric field enhancement than that made of polystyrene. Influenza virus detection was also demonstrated using glass chips, and a detection limit of 104 pfu/mL was obtained with a sample volume of 15 µL.

  7. Carbon dioxide assisted sustainability enhancement of pyrolysis of waste biomass: A case study with spent coffee ground.

    Science.gov (United States)

    Cho, Dong-Wan; Cho, Seong-Heon; Song, Hocheol; Kwon, Eilhann E

    2015-01-01

    This work mainly presents the influence of CO2 as a reaction medium in the thermo-chemical process (pyrolysis) of waste biomass. Our experimental work mechanistically validated two key roles of CO2 in pyrolysis of biomass. For example, CO2 expedited the thermal cracking of volatile organic compounds (VOCs) evolved from the thermal degradation of spent coffee ground (SCG) and reacted with VOCs. This enhanced thermal cracking behavior and reaction triggered by CO2 directly led to the enhanced generation of CO (∼ 3000%) in the presence of CO2. As a result, this identified influence of CO2 also directly led to the substantial decrease (∼ 40-60%) of the condensable hydrocarbons (tar). Finally, the morphologic change of biochar was distinctive in the presence of CO2. Therefore, a series of the adsorption experiments with dye were conducted to preliminary explore the physico-chemical properties of biochar induced by CO2.

  8. Patterning ITO by Template-Assisted Colloidal-Lithography for Enhancing Power Conversion Efficiency in Organic Photovoltaic.

    Science.gov (United States)

    Lee, Jin-Su; Yu, Jung-Hun; Hwang, Ki-Hwan; Nam, Sang-Hun; Boo, Jin-Hyo; Yun, Sang H

    2016-05-01

    Highly structured interfaces are very desirable in organic photovoltaic solar cells (OPVs), in order to enhance power conversion efficiency (PCE) by decreasing of the transport path for excited charge carriers in the absorber and increasing the optical path length for photon absorption. Many complicated, high-cost lithographic methods have been attempted to modify the surface of the absorber or substrate. However, solution-based colloidal-lithography processes are scalable and cost-effective, but generally result in non-uniform structured surfaces. In this report, we demonstrated an optimized silica-templated colloidal lithographical approach to create a well-defined and controlled transparent ITO layer for enhancing power conversion efficiency (PCE). Additionally, morphological effects of the patterned ITO on optical properties and PCE were analyzed in detail. PMID:27483864

  9. Dismantlement of nuclear facilities decommissioned from the Russian navy: Enhancing regulatory supervision of nuclear and radiation safety

    Energy Technology Data Exchange (ETDEWEB)

    Sneve, M.K.

    2013-03-01

    The availability of up to date regulatory norms and standards for nuclear and radiation safety, relevant to the management of nuclear legacy situations, combined with effective and efficient regulatory procedures for licensing and monitoring compliance, are considered to be extremely important. Accordingly the NRPA has set up regulatory cooperation programs with corresponding authorities in the Russian Federation. Cooperation began with the civilian regulatory authorities and was more recently extended to include the military authority and this joint cooperation supposed to develop the regulatory documents to improve supervision over nuclear and radiation safety while managing the nuclear military legacy facilities in Northwest Russia and other regions of the country. (Author)

  10. Dismantlement of nuclear facilities decommissioned from the Russian navy: Enhancing regulatory supervision of nuclear and radiation safety

    International Nuclear Information System (INIS)

    The availability of up to date regulatory norms and standards for nuclear and radiation safety, relevant to the management of nuclear legacy situations, combined with effective and efficient regulatory procedures for licensing and monitoring compliance, are considered to be extremely important. Accordingly the NRPA has set up regulatory cooperation programs with corresponding authorities in the Russian Federation. Cooperation began with the civilian regulatory authorities and was more recently extended to include the military authority and this joint cooperation supposed to develop the regulatory documents to improve supervision over nuclear and radiation safety while managing the nuclear military legacy facilities in Northwest Russia and other regions of the country. (Author)

  11. EVFDT: An Enhanced Very Fast Decision Tree Algorithm for Detecting Distributed Denial of Service Attack in Cloud-Assisted Wireless Body Area Network

    Directory of Open Access Journals (Sweden)

    Rabia Latif

    2015-01-01

    Full Text Available Due to the scattered nature of DDoS attacks and advancement of new technologies such as cloud-assisted WBAN, it becomes challenging to detect malicious activities by relying on conventional security mechanisms. The detection of such attacks demands an adaptive and incremental learning classifier capable of accurate decision making with less computation. Hence, the DDoS attack detection using existing machine learning techniques requires full data set to be stored in the memory and are not appropriate for real-time network traffic. To overcome these shortcomings, Very Fast Decision Tree (VFDT algorithm has been proposed in the past that can handle high speed streaming data efficiently. Whilst considering the data generated by WBAN sensors, noise is an obvious aspect that severely affects the accuracy and increases false alarms. In this paper, an enhanced VFDT (EVFDT is proposed to efficiently detect the occurrence of DDoS attack in cloud-assisted WBAN. EVFDT uses an adaptive tie-breaking threshold for node splitting. To resolve the tree size expansion under extreme noise, a lightweight iterative pruning technique is proposed. To analyze the performance of EVFDT, four metrics are evaluated: classification accuracy, tree size, time, and memory. Simulation results show that EVFDT attains significantly high detection accuracy with fewer false alarms.

  12. Safety and adverse effects during 24 hours after contrast-enhanced MRI with gadobenate dimeglumine (MultiHance {sup registered}) in children

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Guenther; Schuerholz, Hellmut; Buecker, Arno; Fries, Peter [Homburg University Hospital, Homburg, Saar (Germany); Kirchin, Miles A. [Bracco Imaging SpA, Milan (Italy)

    2013-02-15

    Gadolinium-based MR contrast agents have long been considered safe for routine diagnostic imaging. However, the advent of nephrogenic systemic fibrosis (NSF) among certain patients with severe renal insufficiency has brought the issue of safety into question. Nowhere is safety of greater concern than among children who frequently require multiple contrast-enhanced MRI examinations over an extended period of time. To retrospectively evaluate the safety of gadobenate dimeglumine for contrast-enhanced (CE) MRI across a range of indications. Two hundred pediatric inpatients (age: 4 days to 15 years) underwent CE MRI as part of clinical routine. The children received a gadobenate dimeglumine dose of either 0.05 mmol/kg body weight (liver, abdominal imaging, musculoskeletal imaging, brain and other rare indications) or 0.1 mmol/kg bodyweight (cardiovascular imaging, MR-urography). Young (< 8 years) children with congenital heart disease were intubated and underwent MRA evaluation with controlled ventilation. Monitoring for adverse events was performed for at least 24 h after each gadobenate dimeglumine injection. Depending on clinical necessity, laboratory measurements and, in some cases, vital sign and ECG determinations were made before and after contrast injection. Safety was evaluated by age group, indication and dose administered. No clinically adverse events were reported among children who had one MRI scan only or among children who had several examinations. There were no changes in creatinine or bilirubin levels even in very young children. No adverse events were recorded during the first 24 h following administration of gadobenate dimeglumine in 200 children. (orig.)

  13. Vortex-assisted surfactant-enhanced emulsification liquid-liquid microextraction for the determination of carbamates in juices by micellar electrokinetic chromatography tandem mass spectrometry.

    Science.gov (United States)

    Moreno-González, David; Huertas-Pérez, José F; García-Campaña, Ana M; Gámiz-Gracia, Laura

    2015-07-01

    A new method based on vortex-assisted surfactant-enhanced-emulsification liquid-liquid microextraction has been developed for the extraction of carbamate pesticides in juice samples prior to their determination by micellar electrokinetic chromatography coupled to tandem mass spectrometry. This sample treatment allowed the satisfactory extraction and the extract clean-up of 25 carbamates from different fruit and vegetal juices (banana, tomato, and peach). In this study, the addition of ammonium perfluorooctanoate in the aqueous sample in combination with vortex agitation, provided very clean extracts with short extraction times. Under optimized conditions, recoveries of the proposed method for these pesticides from fortified juice samples ranged from 81% to 104%, with relative standard deviations lower than 15%. Limits of quantification were between 2.3µgkg(-)(1) and 4.7µgkg(-)(1), showing the high sensitivity of this fast and simple method. PMID:25882424

  14. Microwave assisted facile hydrothermal synthesis and characterization of zinc oxide flower grown on graphene oxide sheets for enhanced photodegradation of dyes

    Science.gov (United States)

    Kashinath, L.; Namratha, K.; Byrappa, K.

    2015-12-01

    Microwave assisted hydrothermal process of synthesis of ZnO-GO nanocomposite by using ZnCl2 and NaOH as precursors is being reported first time. In this investigation, a novel route to study on synthesis, interaction, kinetics and mechanism of hybrid zinc oxide-graphene oxide (ZnO-GO) nanocomposite using microwave assisted facile hydrothermal method has been reported. The results shows that the ZnO-GO nanocomposite exhibits an enhancement and acts as stable photo-response degradation performance of Brilliant Yellow under the UV light radiation better than pure GO and ZnO nanoparticles. The microwave exposure played a vital role in the synthesis process, it facilitates with well define crystalline structure, porosity and fine morphology of ZnO/GO nanocomposite. Different molar concentrations of ZnO precursors doped to GO sheets were been synthesized, characterized and their photodegradation performances were investigated. The optical studies by UV-vis and Photo Luminescence shows an increase in band gap of nanocomposite, which added an advantage in photodegradation performance. The in situ flower like ZnO nano particles are were densely decorated and anchored on the surfaces of graphene oxide sheets which aids in the enhancement of the surface area, adsorption, mass transfer of dyes and evolution of oxygen species. The nanocomposite having high surface area and micro/mesoporous in nature. This structure and morphology supports significantly in increasing photo catalytic performance legitimate to the efficient photosensitized electron injection and repressed electron recombination due to electron transfer process with GO as electron collector and transporter dependent on the proportion of GO in ZnO/GO composite.

  15. Enhancing the implementation of Occupational Health and Safety interventions through a design of the socio-technical interaction

    DEFF Research Database (Denmark)

    Masi, Donato; Cagno, E.; Hasle, Peter;

    2014-01-01

    A multitude of Occupational Health and Safety (OHS) interventions have proven to be effective under controlled conditions, but their implementation in practice is often difficult and interventions may therefore not work as expected, especially when referring to Small and Medium sized Enterprises...

  16. The level of knowledge and radiation safety practice amongst cardiovascular technology, medical assistant, nursing and diagnostic radiography students and dose monitoring in radiography laboratory of Kolej Islam Sains dan Teknologi, Kelantan

    International Nuclear Information System (INIS)

    Full-text: This study investigated the knowledge level and practices regarding radiation safety among the cardiovascular technology, medical assistant nursing and radiography diagnostic students of Kolej Islam Sains dan Teknologi (KIST). The objectives of this study are to monitor the dose rate at radiography lab and to propose the guideline on radiation safety topics to improve the syllabus. 274 respondents including 30 psychology students acting as the control group were asked to answer questions from the questionnaires which cover the topics of basic knowledge of radiation and radiation safety practice. There was a significant difference (p < 0.05) between the correct answers and courses for 18 questions except for the question 4. There was a significant different (p < 0.05) between the correct answers and year of study for the questions 4, 5, 7, 12 to 15 and 18 to 20. There was a significance different (p < 0.05) between the correct answers and gender for questions 7, 11 and 19. For area dose monitoring in the radiography diagnostic lab, the assessment report on film batches of 4 walls in the lab were recorded and Victoreen451-RYR survey meter was used to monitor the dose rate for 7 selected areas with the exposure factors set for the chest, abdomen, upper extremity, lower extremity and skull radiography examinations. The dose rates at area 1 to 4, area 5 during the examination of chest, abdomen and skull, area 6 during the examination of abdomen and area 7 during the examination of abdomen, had exceeded the dose limit for radiation worker. The dose rate at the area 1 and 4 are slightly higher than the other areas. The contributing factors are the distance, tube potential, collimation and X-ray tube angulation. This study had shown that the cardiovascular technology and diagnostic radiography students have better knowledge and radiation safety practice level than the medical assistant and nursing students. In general, the level of knowledge and radiation safety

  17. Enhancement effects of ultrasound assisted in the synthesis of NiAl hydrotalcite for carbonyl sulfide removal.

    Science.gov (United States)

    Zhao, Shunzheng; Yi, Honghong; Tang, Xiaolong; Gao, Fengyu; Yu, Qingjun; Zhou, Yuansong; Wang, Jiangen; Huang, Yonghai; Yang, Zhongyu

    2016-09-01

    Ultrasonic effect in the synthesis of catalysts of NiAl oxides prepared starting from the coprecipitation method of a hydrotalcite structure was evaluated in this work. Removal of carbonyl sulfide (COS) at low temperature over the hydrotalcite-derived oxides was studied. The samples were characterized by X-ray Diffraction (XRD), scanning electron microscope (SEM), N2 adsorption/desorption techniques, Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and CO2 temperature-programmed desorption (TPD). It is found that hydrotalcite treated with ultrasonic has smaller average crystallite size and higher particle dispersion compared to hydrotalcite without ultrasonic treatment. As a result, mixed oxides derived from hydrotalcite treated with ultrasonic show more developed pore structure which is good for the physical adsorption of gaseous pollutant. The result of desulfuration test showed that removal efficiency of COS on the NiAl mixed oxides prepared by ultrasonic method (30min) is greater than that on the catalyst prepared without the ultrasonic irradiation assistance with the same aging time. One important reason for the high activity is that when the ultrasonic is used the number of weak basic sites (OH(-) groups) and moderate basic sites (M-O) was increased, whereas the number of strong basic sites (O(2-)) was decreased. Therefore, ultrasonic treatment promoted the COS hydrolysis and suppress the poisoning of the catalyst. PMID:27150779

  18. Enhancing Jatropha oil extraction yield from the kernels assisted by a xylan-degrading bacterium to preserve protein structure

    OpenAIRE

    Marasabessy, Ahmad; Moeis, Maelita R; Sanders, Johan P. M.; Weusthuis, Ruud A.

    2011-01-01

    We investigated the use of bacterial cells isolated from paddy crab for the extraction of oil from Jatropha seed kernels in aqueous media while simultaneously preserving the protein structures of this protein-rich endosperm. A bacterial strain—which was marked as MB4 and identified by means of 16S rDNA sequencing and physiological characterization as either Bacillus pumilus or Bacillus altitudinis—enhanced the extraction yield of Jatropha oil. The incubation of an MB4 starter culture with pre...

  19. United States Program for Technical assistance to IAEA Standards. Concept Paper: Knowledge Acquisition, Skills training for enhanced IAEA safeguards inspections

    Energy Technology Data Exchange (ETDEWEB)

    Morris, F.A.; Toquam, J.L.

    1993-11-01

    This concept paper explores the potential contribution of ``Knowledge Acquisition Skills`` in enhancing the effectiveness of international safeguards inspections by the International Atomic energy Agency (IAEA, or Agency) and identifies types of training that could be provided to develop or improve such skills. For purposes of this concept paper, Knowledge Acquisition Skills are defined broadly to include all appropriate techniques that IAEA safeguards inspectors can use to acquire and analyze information relevant to the performance of successful safeguards inspections. These techniques include a range of cognitive, analytic, judgmental, interpersonal, and communications skills that have the potential to help IAEA safeguards inspectors function more effectively.

  20. 46th Annual meeting on nuclear technology (AMNT 2015). Key topic / Enhanced safety and operation excellence / Sustainable reactor operation management - safe, efficient, valuable

    International Nuclear Information System (INIS)

    Summary report on the following Topical Session of the 46th Annual Conference on Nuclear Technology (AMNT 2015) held in Berlin, 5 to 7 May 2015: - Sustainable Reactor Operation Management - Safe, Efficient, Valuable (Erwin Fischer) The other Sessions of the Key Topics - ''Outstanding Know-How and Sustainable Innovations'', - ''Enhanced Safety and Operation Excellence'' and - ''Decommissioning Experience and Waste Management Solutions'' have been covered in atw 7 (2015) and will be covered in further issues of atw.

  1. Complex Coil Assisted Single Coil Embolization for Small Intracranial Aneurysm

    OpenAIRE

    Yang, Ming-Shiang; Yang, Tzu-Hsien; Ou, Chang-Hsien; Chan, Si-Wa; Chen, Tai-I; Yang, Chia-Jung; Chiang, Chia-Ming; Huang, Wen-Chien

    2013-01-01

    The purpose of the technical note is to introduce the complex coil assisted coil embolization method in the treatment of intracranial small aneurysm, in order to enhance the safety of the procedure. The first microcatheter was navigated into the aneurysm sac and the ultrasoft coil was used as the embolization coil. If the embolizations coil could not stay within the aneurysm sac smoothly, such as coil herniation into parent artery during the delivery process. The second microcatheter would be...

  2. Bicycle Safety in Action.

    Science.gov (United States)

    National Commission on Safety Education, Washington, DC.

    This material was designed to assist schools in teaching bicycle safety. As the population grows and competition for road space increases, it is more imperative than ever that we concentrate attention on the need for caution among pupil cyclists. The pamphlet: (1) discusses the role of bicycle safety in classroom instruction and in student…

  3. Gold nanoparticles assisted surface enhanced Raman scattering and luminescence of Er{sup 3+} doped zinc–sodium tellurite glass

    Energy Technology Data Exchange (ETDEWEB)

    Ghoshal, S.K.; Awang, Asmahani, E-mail: asmahani_awang@yahoo.com; Sahar, M.R.; Arifin, R.

    2015-03-15

    Significant enhancements in Er{sup 3+} luminescence and Raman intensity mediated via surface plasmon resonance (SPR) of gold (Au) nanoparticles (NPs) embedded zinc–sodium tellurite glass are reported. The observed modifications in the physical and spectroscopic properties are ascribed to the alterations in the glass network. XRD pattern confirms the amorphous nature of prepared glass sample. UV–vis-NIR spectra reveal seven absorption bands. Surface plasmon band is evidenced around 626–630 nm. TEM images manifest the growth of non-spherical Au NPs with average diameter between ∼7.2 nm and 8.6 nm. The visible up-conversion (UC) emission for all samples under 779 nm excitation exhibits three bands centered at 503 nm (green), 546 (green) and 637 nm (red) ascribed to {sup 2}H{sub 11/2}→{sup 4}I{sub 15/2}, {sup 4}S{sub 3/2}→{sup 4}I{sub 15/2} and {sup 4}F{sub 9/2}→{sup 4}I{sub 15/2} transitions. Glass sample with 0.4 mol% Au displaying the highest luminescence intensity with enhancement factor of 3.85 and 3.56 for green bands, and 7.61 for the red band is ascribed to the NPs local field enhancement and energy transfer between rare earth (RE) ions and NPs. FTIR spectra show the vibration of ZnO{sub 4} bonds, Te-O bond in TeO{sub 3} (tp) and TeO{sub 4} (tbp) units and the hydroxyl groups. Raman spectra demonstrate the presence of Er-O and Zn-O bond, anti-symmetric vibrations of Te-O-Te bonds and stretching modes of non-bonded oxygen exists in TeO{sub 3} and TeO{sub 3+1} unit. The amplifications in Raman signals by a factor of 1.62, 1.58, 1.64, 1.68 and 1.69 corresponding to the peak centered at 262 cm{sup −1}, 382 cm{sup −1}, 521 cm{sup −1}, 670 cm{sup −1} and 725 cm{sup −1} are attributed to the contribution of a surface plasmon generating a strong, localized and secondary field. We assert that our glass compositions offer favorable potential to develop solid state lasers and other versatile nanophotonic devices. - Highlights: • Gold

  4. Genetic expression programming-based DBA for enhancing peer-assisted music-on-demand service in EPON

    Science.gov (United States)

    Liem, Andrew Tanny; Hwang, I.-Shyan; Nikoukar, AliAkbar; Lee, Jhong-Yue

    2015-03-01

    Today, the popularity of peer-assisted music-on-demand (MoD) has increased significantly worldwide. This service allows users to access large music library tracks, listen to music, and share their playlist with other users. Unlike the conventional voice traffic, such an application maintains music quality that ranges from 160 kbps to 320 kbps, which most likely consumes more bandwidth than other traffics. In the access network, Ethernet passive optical network (EPON) is one of the best candidates for delivering such a service because of being cost-effective and with high bandwidth. To maintain music quality, a stutter needs to be prevented because of either network effects or when the due user was not receiving enough resources to play in a timely manner. Therefore, in this paper, we propose two genetic expression programming (GEP)-based dynamic bandwidth allocations (DBAs). The first DBA is a generic DBA that aims to find an optimum formula for voice, video, and data services. The second DBA aims to find optimum formulas so that Optical Line Terminal (OLT) can satisfy not only the voice and Peer-to-Peer (P2P) MoD traffics but also reduce the stutter. Optical Network Unit (ONU) traits such as REPORT and GATE messages, cycle time, and mean packet delay are set to be predictor variables. Simulation results show that our proposed DBAs can satisfy the voice and P2P MoD services packet delay and monitor other overall system performances such as expedited forwarding (EF) jitter, packet loss, bandwidth waste, and system throughputs.

  5. Word processing as an assistive technology tool for enhancing academic outcomes of students with writing disabilities in the general classroom.

    Science.gov (United States)

    Hetzroni, Orit E; Shrieber, Betty

    2004-01-01

    This study investigated the use of a word processor for enhancing the academic outcomes of three students with writing disabilities in a junior high school. A single-subject ABAB design was used to compare academic output produced during class time with and without a computer equipped with a word processor. The number of spelling errors, the number of reading errors, and the number of words used per text were counted, and the overall structure and organization of text were examined across all in-class materials. The data demonstrated a clear difference between handwritten and computer phases. In traditional paper-and-pencil phases, students produced outcomes that had more spelling mistakes, more reading errors, and lower overall quality of organization and structure in comparison with the phases in which a computer equipped with a word processor was used. The results did not indicate any noticeable difference in the number of words per text. Implications and future research directions are discussed.

  6. Mesoporous gold sponges: electric charge-assisted seed mediated synthesis and application as surface-enhanced Raman scattering substrates

    Science.gov (United States)

    Yi, Zao; Luo, Jiangshan; Tan, Xiulan; Yi, Yong; Yao, Weitang; Kang, Xiaoli; Ye, Xin; Zhu, Wenkun; Duan, Tao; Yi, Yougen; Tang, Yongjian

    2015-11-01

    Mesoporous gold sponges were prepared using 4-dimethylaminopyridine (DMAP)-stabilized Au seeds. This is a general process, which involves a simple template-free method, room temperature reduction of HAuCl4·4H2O with hydroxylamine. The formation process of mesoporous gold sponges could be accounted for the electrostatic interaction (the small Au nanoparticles (~3 nm) and the positively charged DMAP-stabilized Au seeds) and Ostwald ripening process. The mesoporous gold sponges had appeared to undergo electrostatic adsorption initially, sequentially linear aggregation, welding and Ostwald ripening, then, they randomly cross link into self-supporting, three-dimensional networks with time. The mesoporous gold sponges exhibit higher surface area than the literature. In addition, application of the spongelike networks as an active material for surface-enhanced Raman scattering has been investigated by employing 4-aminothiophenol (4-ATP) molecules as a probe.

  7. The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma

    DEFF Research Database (Denmark)

    Skjøth-Rasmussen, Jane; Bøgeskov, Lars; Sehested, Astrid;

    2015-01-01

    . METHODS: The child was pretreated with 3 × 4 mg dexamethasone for 4 days prior to the second surgery. At 5 a.m. on the day of surgery, a freshly prepared solution of 5-ALA (20 mg/kg body weight; Medac, Germany) was given orally. RESULTS: At surgery, through the original opening, the vague red fluorescence...... of the tumor was clearly distinctive from the cerebellum with no tumor infiltration. All fluorescent tissue was removed. Postoperative MRI gave suspicion of yet at small tumor residue, but this structure is less than 1.5 ml in calculated volume, and consequently the recommended adjuvant therapy of the child...... changed from the high-risk medulloblastoma regimen to the standard-risk regimen. CONCLUSIONS: In this particular difficult case of non-contrast-enhancing tumor, 5-ALA was of vital importance to improve rate of resection and change the aggressiveness needed in postsurgery radiation therapy....

  8. Nuclear safety regulations

    International Nuclear Information System (INIS)

    The enactment of nuclear safety regulations in 1996 is mainly focused on the preparation of related regulations, and safety guides for nuclear materials control, the reprocessing installations of spent fuels, the treatment and disposal for radioactive waste. The NNSA also assists the departments concerned of the State Council for modification on the 'Atomic Energy Act' (draft) and the' Regulations on the Safety Supervision and Control of Radioactive Materials Transportation' (draft)

  9. Ultrastrong Freestanding Graphene Oxide Nanomembranes with Surface-Enhanced Raman Scattering Functionality by Solvent-Assisted Single-Component Layer-by-Layer Assembly.

    Science.gov (United States)

    Xiong, Rui; Hu, Kesong; Zhang, Shuaidi; Lu, Canhui; Tsukruk, Vladimir V

    2016-07-26

    We report single-component ultrathin reduced graphene oxide (rGO) nanomembranes fabricated via nonconventional layer-by-layer assembly (LbL) of graphene oxide flakes, using organic solvent instead of water to provide strong complementary interactions and to ensure the uniform layered growth. This unique approach does not require regular polymeric from the assembly process or intermediate surface chemical modification. The resulting ultrastrong freestanding graphene oxide (rGO) LbL nanomembranes with a very low thickness of 3 nm (three GO monolayers) can be transferred over a large surface area across tens of square centimeters by using a facile surface-tension-assisted release technique. These uniform and ultrasmooth nanomembranes with high transparency (up to 93% at 550 nm) and high electrical conductivity (up to 3000 S/m) also exhibit outstanding mechanical strength of 0.5 GPa and a Young's modulus of 120 GPa, which are several times higher than that of other reported regular rGO films. Furthermore, up to 94 wt % of silver nanoplates can be sandwiched between 5 nm GO layers to construct a flexible freestanding protected noble metal monolayer with surface-enhanced Raman scattering properties. These flexible rGO/Ag/rGO nanomembranes can be transferred and conformally coat complex surfaces and show a cleaner Raman signature, enhanced wet stability, and lower oxidation compared to bare Ag nanostructures. PMID:27331853

  10. Ionic-liquid-based, manual-shaking- and ultrasound-assisted, surfactant-enhanced emulsification microextraction for the determination of three fungicide residues in juice samples.

    Science.gov (United States)

    Chen, Xiaochu; You, Xiangwei; Liu, Fengmao; Hou, Fan; Zhang, Xu

    2015-01-01

    A novel manual-shaking- and ultrasound-assisted surfactant-enhanced emulsification microextraction method was developed for the determination of three fungicides in juice samples. In this method, the ionic liquid, 1-ethyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide, instead of a volatile organic solvent was used as the extraction solvent. The surfactant, NP-10, was used as an emulsifier to enhance the dispersion of the water-immiscible ionic liquid into an aqueous phase, which accelerated the mass transfer of the analytes. Organic dispersive solvent typically required in common dispersive liquid-liquid microextraction methods was not necessary. In addition, manual shaking for 15 s before ultrasound to preliminarily mix the extraction solvent and the aqueous sample could greatly shorten the time for dispersing the ionic liquid into aqueous solution by ultrasound irradiation. Several experimental parameters affecting the extraction efficiency, including type and volume of extraction solvent, type and concentration of surfactant, extraction time, and pH, were optimized. Under the optimized conditions, good linearity with the correlation coefficients (γ) higher than 0.9986 and high sensitivity with the limit of detection ranging from 0.4 to 1.6 μg/L were obtained. The average recoveries ranged from 61.4 to 86.0% for spiked juice, with relative standard deviations from 1.8 to 9.7%. The proposed method was demonstrated to be a simple, fast, and efficient method for the analysis of the target fungicides in juice samples. PMID:25394281

  11. Refinement and growth enhancement of Al2Cu phase during magnetic field assisting directional solidification of hypereutectic Al-Cu alloy

    Science.gov (United States)

    Wang, Jiang; Yue, Sheng; Fautrelle, Yves; Lee, Peter D.; Li, Xi; Zhong, Yunbo; Ren, Zhongming

    2016-04-01

    Understanding how the magnetic fields affect the formation of reinforced phase during solidification is crucial to tailor the structure and therefor the performance of metal matrix in situ composites. In this study, a hypereutectic Al-40 wt.%Cu alloy has been directionally solidified under various axial magnetic fields and the morphology of Al2Cu phase was quantified in 3D by means of high resolution synchrotron X-ray tomography. With rising magnetic fields, both increase of Al2Cu phase’s total volume and decrease of each column’s transverse section area were found. These results respectively indicate the growth enhancement and refinement of the primary Al2Cu phase in the magnetic field assisting directional solidification. The thermoelectric magnetic forces (TEMF) causing torque and dislocation multiplication in the faceted primary phases were thought dedicate to respectively the refinement and growth enhancement. To verify this, a real structure based 3D simulation of TEMF in Al2Cu column was carried out, and the dislocations in the Al2Cu phase obtained without and with a 10T high magnetic field were analysed by the transmission electron microscope.

  12. Large-area one-step assembly of three-dimensional porous metal micro/nanocages by ethanol-assisted femtosecond laser irradiation for enhanced antireflection and hydrophobicity.

    Science.gov (United States)

    Li, Guoqiang; Li, Jiawen; Zhang, Chenchu; Hu, Yanlei; Li, Xiaohong; Chu, Jiaru; Huang, Wenhao; Wu, Dong

    2015-01-14

    The capability to realize 2D-3D controllable metallic micro/nanostructures is of key importance for various fields such as plasmonics, electronics, bioscience, and chemistry due to unique properties such as electromagnetic field enhancement, catalysis, photoemission, and conductivity. However, most of the present techniques are limited to low-dimension (1D-2D), small area, or single function. Here we report the assembly of self-organized three-dimensional (3D) porous metal micro/nanocages arrays on nickel surface by ethanol-assisted femtosecond laser irradiation. The underlying formation mechanism was investigated by a series of femtosecond laser irradiation under exposure time from 5 to 30 ms. We also demonstrate the ability to control the size of micro/nanocage arrays from 0.8 to 2 μm by different laser pulse energy. This method features rapidness (∼10 min), simplicity (one-step process), and ease of large-area (4 cm(2) or more) fabrication. The 3D cagelike micro/nanostructures exhibit not only improved antireflection from 80% to 7% but also enhanced hydrophobicity from 98.5° to 142° without surface modification. This simple technique for 3D large-area controllable metal microstructures will find great potential applications in optoelectronics, physics, and chemistry. PMID:25473879

  13. GeneOptimizer program-assisted cDNA reengineering enhances sRAGE autologous expression in Chinese hamster ovary cells.

    Science.gov (United States)

    Wei, Wen; Kim, Ji Min; Medina, Danny; Lakatta, Edward G; Lin, Li

    2014-03-01

    Soluble receptor for advanced glycation end products (sRAGE) is a secreted mammalian protein that functions as a decoy to counter-react RAGE signaling-resultant pathological conditions, and has high therapeutic potentials. Our prior studies showed that recombinant human sRAGE expressed in Chinese hamster, Ceanothus griseus, ovary (CHO) cells is modified by specific N-glycosylation, and exhibits higher bioactivity than that expressed in other host systems including insect Spodoptera frugiperda cells. Here, we show that GeneOptimizer software program-assisted, reengineered sRAGE cDNA enhances the recombinant protein expression in CHO cells. The cDNA sequence encoding human sRAGE was optimized for RNA structure, stability, and codon usages in CHO cells. We found that such optimization augmented sRAGE expression over 2 folds of its wild-type counterpart. We also studied how individual parameter impacted sRAGE autologous expression in CHO cells, and whether sRAGE bioactivity was compromised. We found that the enhanced expression appeared not to affect sRAGE N-glycosylation and bioactivity. Optimization of sRAGE expression provides a basis for future large-scale production of this protein to meet medical needs. PMID:24373844

  14. Ionic liquid-assisted bidirectional regulation strategy for carbon quantum dots (CQDs)/Bi4O5I2 nanomaterials and enhanced photocatalytic properties.

    Science.gov (United States)

    Ji, Mengxia; Xia, Jiexiang; Di, Jun; Wang, Bin; Yin, Sheng; Xu, Li; Zhao, Junze; Li, Huaming

    2016-09-15

    In this study, novel visible-light-driven carbon quantum dots (CQDs)/Bi4O5I2 material has been prepared via a reactable ionic liquid 1-hexyl-3-methylimidazolium iodide ([Hmim]I) assisted bidirectional regulation solvothermal method. This is the first time for the preparation of CQDs/Bi4O5I2 material with halogen and CQDs bidirectional regulation at the same time. With CQDs modified on the surface of Bi4O5I2, fast transfer of photogenerated charges and low recombination of photo-induced electron-hole pairs facilitated the enhancement of photodegradation activity. At the same time, the introduction of CQDs made the electrons occupied in high-energy potential on the conduction band of Bi4O5I2 transfer to the reaction center CQDs and the molecular oxygen can be thus activated. The enhanced mechanisms for the active species (holes, hydroxyl and superoxide radicals) during the photocatalytic reaction under visible irradiation were analyzed using DRS analysis, electron spin resonance (ESR) technique and free radicals trapping experiments. PMID:27318012

  15. Personalized medicine in human space flight: using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance

    OpenAIRE

    Schmidt, Michael A.; Goodwin, Thomas J.

    2013-01-01

    Space flight is one of the most extreme conditions encountered by humans. Advances in Omics methodologies (genomics, transcriptomics, proteomics, and metabolomics) have revealed that unique differences exist between individuals. These differences can be amplified in extreme conditions, such as space flight. A better understanding of individual differences may allow us to develop personalized countermeasure packages that optimize the safety and performance of each astronaut. In this review, we...

  16. 46{sup th} annual meeting on nuclear technology (AMNT 2015). Key topic / Enhanced safety and operation excellence

    Energy Technology Data Exchange (ETDEWEB)

    Traichel, Anke [NUKEM Technologies, Alzenau (Germany). Department of Safety Engineering and Assessment/Proposals Engineering

    2016-02-15

    Summary report on the Technical Session ''Operation and Safety of Nuclear Installations, Fuel - Special Issues'' of the 46{sup th} Annual Conference on Nuclear Technology (AMNT 2015) held in Berlin, 5 to 7 May 2015. Other Sessions of AMNT 2015 have been covered in atw 7 to 12 (2015), 1 (2016) and will be covered in further issues of atw.

  17. Development of dual cooled annular fuel and its possibility to enhance both economy and safety of light water reactor

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Yanghyun; Kim, Keonsik; Park, Jeongyong; Yang, Yongsik; Kim, Hyungkyu; In, Wangkee; Song, Kunwoo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-03-15

    Over the past few decades, extensive studies have been performed to improve the reliability and safety of light water reactor (LWR) fuel. In recent years, power updating of about 10% is being achieved by modifying safety analysis methodology and subsequent increase in safety margin. But departure from nucleate boiling (DNB) and loss of coolant accident (LOCA) are still two of the most important limiting factors which would restrict power updating more than 10%. Duel cooled annular fuel, cooled in both internal and external cooling channel, has advantages of considerably lower heat flux and lower fuel temperature than conventional solid fuel. While lower heat flus gives higher DNB margin for the same power retie, lower temperature reduces the stored energy of fuel. However, there are many technical issues that should be addressed before any new type of fuel can be considered for application to LWR. This paper describes the key technologies that Korea Atomic Energy Research Institute (KAERI) has developed for dual cooled annular fuel and discusses the feasibility of its application to LWR.

  18. Development of dual cooled annular fuel and its possibility to enhance both economy and safety of light water reactor

    International Nuclear Information System (INIS)

    Over the past few decades, extensive studies have been performed to improve the reliability and safety of light water reactor (LWR) fuel. In recent years, power updating of about 10% is being achieved by modifying safety analysis methodology and subsequent increase in safety margin. But departure from nucleate boiling (DNB) and loss of coolant accident (LOCA) are still two of the most important limiting factors which would restrict power updating more than 10%. Duel cooled annular fuel, cooled in both internal and external cooling channel, has advantages of considerably lower heat flux and lower fuel temperature than conventional solid fuel. While lower heat flus gives higher DNB margin for the same power retie, lower temperature reduces the stored energy of fuel. However, there are many technical issues that should be addressed before any new type of fuel can be considered for application to LWR. This paper describes the key technologies that Korea Atomic Energy Research Institute (KAERI) has developed for dual cooled annular fuel and discusses the feasibility of its application to LWR

  19. SU-E-I-45: Feasibility for Using Iodine Quantification to Assist Diagnosis in Dual Energy Contrast-Enhanced Digital Mammography

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Y [Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan (China); Lin, Y; Tsai, C [Chang Gung University, Taoyuan, Taiwan (China); Cheung, Y [Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan (China); Chang Gung Memorial Hospital at Taoyuan, Taoyuan, Taiwan (China)

    2015-06-15

    Purpose: The objective of this study is to develop quantitative calibration between image quality indexes and iodine concentration with dual-energy (DE) contrast-enhanced digital mammography (CEDM) techniques and further serve as the assistance for diagnosis. Methods: Custom-made acrylic phantom with dimensions of 24×30 cm{sup 2} simulated breast thickness from 2 to 6 cm was used in the calibration. The phantom contained matrix of four times four holes of 3 mm deep with a diameter of 15 mm for filling contrast agent with area density ranged from 0.1 to 10 mg/cm{sup 2}. All the image acquisitions were performed on a full-field digital mammography system (Senographe Essential, GE) with dual energy acquisitions. Mean pixel value (MPV), and contrast-to-noise ratio (CNR) were used for evaluating the relationship between image quality indexes and iodine concentration. Iodine map and CNR map could further be constructed with these calibration curves applied pixel by pixel utilized MATLAB software. Minimum iodine concentration could also be calculated with the visibility threshold of CNR=5 according the Rose model. Results: When evaluating the DE subtraction images, MPV increased linearly as the iodine concentration increased with all the phantom thickness surveyed (R{sup 2} between 0.989 and 0.992). Lesions with increased iodine uptake could thus be enhanced in the color-encoded iodine maps, and the mean iodine concentration could be obtained through the ROI measurements. As for investigating CNR performance, linear relationships were also shown between the iodine concentration and CNR (R{sup 2} between 0.983 and 0.990). Minimum iodine area density of 1.45, 1.73, 1.80, 1.73 and 1.72 mg/cm{sup 2} for phantom thickness of 2, 3, 4, 5, 6 cm were calculated based on Rose’s visualization criteria. Conclusion: Quantitative calibration between image quality indexes and iodine concentrations may further serving as the assistance for analyzing contrast enhancement for patient

  20. Tailoring the surface properties of polypropylene films through cold atmospheric pressure plasma (CAPP) assisted polymerization and immobilization of biomolecules for enhancement of anti-coagulation activity

    Science.gov (United States)

    Navaneetha Pandiyaraj, K.; Ram Kumar, M. C.; Arun Kumar, A.; Padmanabhan, P. V. A.; Deshmukh, R. R.; Bah, M.; Ismat Shah, S.; Su, Pi-Guey; Halleluyah, M.; Halim, A. S.

    2016-05-01

    Enhancement of anti-thrombogenic properties of polypropylene (PP) to avert the adsorption of plasma proteins (fibrinogen and albumin), adhesion and activation of the platelets are very important for vast biomedical applications. The cold atmospheric pressure plasma (CAPP) assisted polymerization has potential to create the specific functional groups such as Osbnd Cdbnd O, Cdbnd O, Csbnd N and Ssbnd S. on the surface of polymeric films using selective precursor in vapour phase to enhance anti-thrombogenic properties. Such functionalized polymeric surfaces would be suitable for various biomedical applications especially to improve the blood compatibility. The eventual aspiration of the present investigation is to develop the biofunctional coating onto the surface of PP films using acrylic acid (AAc) and polyethylene glycol (PEG) as a precursor in a vapour phase by incorporating specific functional groups for immobilization of biomolecules such as heparin (HEP), chitosan (CHI) and insulin (INS) on the surface of plasma modified PP films. The surface properties such as hydrophilicity, chemical composition, surface topography of the surface modified PP films were analyzed by contact angle (CA), Fourier transform infrared spectroscopy (FTIR), X-ray photo electron spectroscopy (XPS) and atomic force microscopy (AFM). Furthermore the anti-thrombogenic properties of the surface modified PP films were studied by in vitro tests which include platelet adhesion and protein adsorption analysis. It was found that the anti-thrombogenic properties of the PP films are effectively controlled by the CAPP grafting of AAc and PEG followed by immobilization of biomolecules of heparin, chitosan and insulin. The grafting and immobilization was confirmed by FTIR and XPS through the recognition of specific functional groups such as COOH, Csbnd O, Ssbnd S and Csbnd N. on the surface of PP film. Furthermore, the surface morphology and hydrophilic nature of the PP films also tailored

  1. Safety first!

    CERN Document Server

    2016-01-01

    Among the many duties I assumed at the beginning of the year was the ultimate responsibility for Safety at CERN: the responsibility for the physical safety of the personnel, the responsibility for the safe operation of the facilities, and the responsibility to ensure that CERN acts in accordance with the highest standards of radiation and environmental protection.   The Safety Policy document drawn up in September 2014 is an excellent basis for the implementation of Safety in all areas of CERN’s work. I am happy to commit during my mandate to help meet its objectives, not least by ensuring the Organization makes available the necessary means to achieve its Safety objectives. One of the main objectives of the HSE (Occupational Health and Safety and Environmental Protection) unit in the coming months is to enhance the measures to minimise CERN’s impact on the environment. I believe CERN should become a role model for an environmentally-aware scientific research laboratory. Risk ...

  2. Screening computer-assisted dosage programs for anticoagulation with warfarin and other vitamin K antagonists: minimum safety requirements for individual programs

    DEFF Research Database (Denmark)

    Poller, L; Roberts, C; Ibrahim, S;

    2009-01-01

    Based on the results of the previous European Action on Anticoagulation (EAA) multicenter study, a simplified minimum procedure is described for screening the safety and effectiveness of marketed programs for dosage of oral anticoagulant drugs (vitamin K antagonists). The aim was to demonstrate non...

  3. Development of an Accessible Audio Computer-Assisted Self-Interview (A-CASI) to Screen for Abuse and Provide Safety Strategies for Women with Disabilities

    Science.gov (United States)

    Oschwald, Mary; Renker, Paula; Hughes, Rosemary B.; Arthur, Anne; Powers, Laurie E.; Curry, Mary Ann

    2009-01-01

    To increase safety and minimize the risk of interpersonal violence, it is critical that women with disabilities and Deaf women have an opportunity to identify whether or not abuse is happening in their lives. Awareness and knowledge of what constitutes abusive behaviors is an essential first step in addressing interpersonal violence. This article…

  4. 临床病人安全用药的管理方法与效果%Methods and effects of enhancing clinical meditation safety management

    Institute of Scientific and Technical Information of China (English)

    霍世英; 黄叶莉; 蔡伟萍; 黄海燕; 田宇红; 董媛媛

    2012-01-01

    目的 探讨临床病人安全用药的管理方法与效果,从而减少给药差错发生,保障病人安全用药.方法 对38例发生给药差错病例进行分析,采取举办给药差错案例分析讨论会、强化护士给药安全意识、加强查对制度的督查、加强有效沟通的培训与督查等安全管理措施.结果 实施临床病人安全用药管理后降低了给药差错发生率(P<0.01).结论 加强临床病人安全用药管理,可有效减少给药差错的发生.%Objective To explore the methods and effects of clinical meditation safety management, then to reduce meditation errors and ensure patients safety. Methods Thirty - eight cases of meditation errors were retrospectively analyzed and the countermeasures were developed according to the causes,including strengthening the meditation safety awareness of nurses, reinforcing the supervision systems and training skills to improve communication, and so on. Results The incidence of meditation errors was reduced significantly (P < 0.01). Conclusion Enhancing the management of clinical meditation safety can effectively reduce the incidence of meditation errors.

  5. Quality Computer Assisted Mobile Learning (CAML and Distance Education Leadership in Managing Technology Enhanced Learning Management System (TELMS in the Malaysian Public Tertiary Education

    Directory of Open Access Journals (Sweden)

    Lee Tan Luck

    2009-07-01

    Full Text Available Abstract - The success in the implementation of a quality computer assisted mobile learning and distance education in a Technology Enhanced Learning Management System is highly rely on the academic leadership in managing and application of Information and Communication Technology (ICT in the tertiary level. The effectiveness of its leadership, knowledge, application and management of ICT and learning management system is of utmost important. Successful application and management includes quality and cost effectiveness of universities administration, CAML and distance education leadership development, organizational culture, academic staffs and students’ attitude and their commitment towards teaching and learning process, support towards the usage of state of the art techno-educational facilities, availability of ICT resources, maintenance and funding of a Learning Management System. This paper will discuss the above factors, which present a comprehensive framework for the implementation of a quality CAML and distance education environment in ICT application and management in the Malaysian public universities. Selected Fifty-two respondents from two Malaysian public universities which offer e Learning and distance education with Learning Management System were acquired. A survey questionnaire is used to determine the effectiveness of ICT and mobile learning application management. Data from the questionnaires were analyzed by using non-parametric and parametric statistics testing. Results of this study show there is significant different in the CAML and distance education leadership in TELMS and the application of ICT and its management in the Malaysian public universities. The study will also address the implementation elements necessary for transforming the public universities and its CAML and distance education teaching and learning process into an effective and result oriented computer assisted mobile learning management model in public

  6. Bio-template-assisted synthesis of hierarchically hollow SiO2 microtubes and their enhanced formaldehyde adsorption performance

    Science.gov (United States)

    Le, Yao; Guo, Daipeng; Cheng, Bei; Yu, Jiaguo

    2013-06-01

    The indoor air quality is crucial for human health, taking into account that people often spend more than 80% of their time in houses, offices and cars. Formaldehyde (HCHO) is a major pollutant and long-term exposure to HCHO may cause health problems such as nasal tumors and skin irritation. In this work, for the first time, hierarchically hollow silica microtubes (HHSM) were synthesized by a simple sol-gel and calcination method using cetyltrimethyl ammonium bromide (CTAB) and bio-template poplar catkin (PC) as co-templates and the PC/SiO2 weight ratio R was varied from 0, 0.1, 0.3 and 1. The prepared samples were further modified with tetraethylenepentamine (TEPA) and characterized by scanning electron microscope (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS), differential thermal analysis (DTA), thermal gravimetric analysis (TGA), and N2 physisorption techniques. This was followed by formaldehyde adsorption tests at ambient temperature. The results showed that all the prepared HHSM samples contained small mesopores with peak pore size at ca. 2.5 nm and large several tens of nanometer-sized pores on the tube wall. The R exhibited an obvious influence on specific surface areas and the sample prepared at R = 0.3 exhibited highest specific surface area (896 m2/g). All the TEPA-modified samples exhibited enhanced formaldehyde adsorption performance. The maximum HCHO adsorption capacity (20.65 mg/g adsorbent) was achieved on the sample prepared at R = 0.3 and modified by 50 wt.% TEPA. The present study will provide new insight for the utilization of bio-template used for the fabrication of inorganic hollow tubes with high HCHO adsorption performance for indoor air purification.

  7. Bio-template-assisted synthesis of hierarchically hollow SiO{sub 2} microtubes and their enhanced formaldehyde adsorption performance

    Energy Technology Data Exchange (ETDEWEB)

    Le, Yao; Guo, Daipeng; Cheng, Bei; Yu, Jiaguo, E-mail: jiaguoyu@yahoo.com

    2013-06-01

    The indoor air quality is crucial for human health, taking into account that people often spend more than 80% of their time in houses, offices and cars. Formaldehyde (HCHO) is a major pollutant and long-term exposure to HCHO may cause health problems such as nasal tumors and skin irritation. In this work, for the first time, hierarchically hollow silica microtubes (HHSM) were synthesized by a simple sol–gel and calcination method using cetyltrimethyl ammonium bromide (CTAB) and bio-template poplar catkin (PC) as co-templates and the PC/SiO{sub 2} weight ratio R was varied from 0, 0.1, 0.3 and 1. The prepared samples were further modified with tetraethylenepentamine (TEPA) and characterized by scanning electron microscope (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FTIR), X-ray photoelectron spectroscopy (XPS), differential thermal analysis (DTA), thermal gravimetric analysis (TGA), and N{sub 2} physisorption techniques. This was followed by formaldehyde adsorption tests at ambient temperature. The results showed that all the prepared HHSM samples contained small mesopores with peak pore size at ca. 2.5 nm and large several tens of nanometer-sized pores on the tube wall. The R exhibited an obvious influence on specific surface areas and the sample prepared at R = 0.3 exhibited highest specific surface area (896 m{sup 2}/g). All the TEPA-modified samples exhibited enhanced formaldehyde adsorption performance. The maximum HCHO adsorption capacity (20.65 mg/g adsorbent) was achieved on the sample prepared at R = 0.3 and modified by 50 wt.% TEPA. The present study will provide new insight for the utilization of bio-template used for the fabrication of inorganic hollow tubes with high HCHO adsorption performance for indoor air purification.

  8. Comparison of the efficacy and safety of video-assisted thoracoscopic surgery with the open method for the treatment of primary pneumothorax in adults

    Directory of Open Access Journals (Sweden)

    Al-Tarshihi Mohammad

    2008-01-01

    Full Text Available Objective : To determine whether video-assisted thoracoscopic surgery is as effective as the traditional open method through axillary thoracotomy for the management of primary spontaneous pneumothorax in adults. Materials and Methods : This retrospective study was conducted at King Hussein Medical Center in the period between March 2002 and March 2007. Eighty-two patients were included in this study. The patients were divided in two groups: group A, which included patients who underwent video-assisted thoracoscopic surgery; and group B, which included patients who underwent open technique through axillary thoracotomy. Efficiency of the procedure, operative time, postoperative complications, length of hospital stay, time to return to work and recurrence were compared between the two groups. Results : There were 79 males (96.3% and 3 females (3.7% with a mean age of 23.7 ± 4.2 years for group A patients and 24.2 ± 4.6 years for group B patients (range 16-37 years. Forty-one patients (50% underwent video-assisted thoracoscopic surgery (group A, and 41 patients (50% underwent open surgical technique through axillary thoracotomy (group B. Postoperative complication occurred in 8 patients (19.3% from among those who underwent open technique and 6 patients (14.6% from among those who underwent thoracoscopic technique. There was no perioperative mortality in both groups. Postoperative pain, volume of blood loss, period of air leak and hospital stay were less in group A, although the operative time was less in group B. Conclusion : Video-assisted thoracoscopic surgery is an efficient and safe method for the treatment of patients with primary pneumothorax in the adults.

  9. Pacific Northwest Laboratory annual report for 1979 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health, and safety

    International Nuclear Information System (INIS)

    Part 5 of the 1979 Annual Report to the Department of Energy Assistant Secretary for the Environment presents Pacific Northwest Laboratory's progress on work performed for the Office of Technology Impacts, the Office of Environmental Compliance and Overview, and the Office of Health and Environmental Research. The report is in four sections, corresponding to the program elements: technology impacts, environmental control engineering, operational and environmental compliance, and human health studies. In each section, articles describe progress made during FY 1979 on individual projects

  10. Vaccine Safety

    Science.gov (United States)

    ... the safety of Tdap, Meningococcal, and HPV vaccines Human Papillomavirus (HPV) Vaccine is Very Safe Read about the safety of ... Hepatitis A Vaccine Safety Hepatitis B Vaccine Safety Human Papillomavirus (HPV) Vaccine Safety FAQs about HPV Safety Influenza (Flu) Vaccine ...

  11. Use of a Graded Approach in the Application of the Safety Requirements for Research Reactors. Specific Safety Guide

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to 'establish or adopt? standards of safety for protection of health and minimization of danger to life and property' - standards that the IAEA must use in its own operations, and which States can apply by means of their regulatory provisions for nuclear and radiation safety. The IAEA does this in consultation with the competent organs of the United Nations and with the specialized agencies concerned. A comprehensive set of high quality standards under regular review is a key element of a stable and sustainable global safety regime, as is the IAEA's assistance in their application. The IAEA commenced its safety standards programme in 1958. The emphasis placed on quality, fitness for purpose and continuous improvement has led to the widespread use of the IAEA standards throughout the world. The Safety Standards Series now includes unified Fundamental Safety Principles, which represent an international consensus on what must constitute a high level of protection and safety. With the strong support of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its standards. Standards are only effective if they are properly applied in practice. The IAEA's safety services encompass design, siting and engineering safety, operational safety, radiation safety, safe transport of radioactive material and safe management of radioactive waste, as well as governmental organization, regulatory matters and safety culture in organizations. These safety services assist Member States in the application of the standards and enable valuable experience and insights to be shared. Regulating safety is a national responsibility, and many States have decided to adopt the IAEA's standards for use in their national regulations. For parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions

  12. Safety, Tolerance, and Enhanced Efficacy of a Bioavailable Formulation of Curcumin With Fenugreek Dietary Fiber on Occupational Stress: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.

    Science.gov (United States)

    Pandaran Sudheeran, Subash; Jacob, Della; Natinga Mulakal, Johannah; Gopinathan Nair, Gopakumar; Maliakel, Abhilash; Maliakel, Balu; Kuttan, Ramadasan; Im, Krishnakumar

    2016-06-01

    Drug delivery systems capable of delivering free (unconjugated) curcuminoids is of great therapeutic significance, since the absorption of bioactive and permeable form plays a key factor in mediating the efficacy of a substance which undergoes rapid biotransformation. Considering the recent understanding on the relatively high bioactivities and blood-brain-barrier permeability of free curcuminoids over their conjugated metabolites, the present human study investigated the safety, antioxidant efficacy, and bioavailability of CurQfen (curcumagalactomannoside [CGM]), a food-grade formulation of natural curcumin with fenugreek dietary fiber that has shown to possess improved blood-brain-barrier permeability and tissue distribution in rats. In this randomized double-blinded and placebo-controlled trial, 60 subjects experiencing occupational stress-related anxiety and fatigue were randomized to receive CGM, standard curcumin, and placebo for 30 days (500 mg twice daily). The study demonstrated the safety, tolerance, and enhanced efficacy of CGM in comparison with unformulated standard curcumin. A significant improvement in the quality of life (P < 0.05) with considerable reduction in stress (P < 0.001), anxiety (P < 0.001), and fatigue (P < 0.001) was observed among CGM-treated subjects as compared with the standard curcumin group, when monitored by SF-36, Perceived Stress Scale with 14 items, and Beck Anxiety Inventory scores. Improvement in the quality of life was further correlated with the significant enhancement in endogenous antioxidant markers (P < 0.01) and reduction in lipid peroxidation (P < 0.001). Further comparison of the free curcuminoids bioavailability after a single-dose (500 mg once per day) and repeated-dose (500 mg twice daily for 30 days) oral administration revealed enhanced absorption and improved pharmacokinetics of CGM upon both single- (30.7-fold) and repeated-dose (39.1-fold) administrations. PMID:27043120

  13. e-MARITIME SERVICES FOR COMMUNICATION WITH CLASS AND FOR ENHANCED SAFETY, SECURITY AND ENVIRONMENTAL PROTECTION IN SHIPPING

    Directory of Open Access Journals (Sweden)

    Erik Vanem

    2014-09-01

    Full Text Available e-Maritime can be considered as an extension of the e-Navigation concept currently being discussed at the International Maritime Organization (IMO. It can be construed to include e-Navigation and promotes the use of all maritime data and information, distributed by way of information and communication technologies, to facilitate maritime transportation and provide value added services. This paper investigates possible e-Maritime services related to safety, security and environmental protection of shipping and for interaction with class. The paper reviews a number of existing services and current initiatives and relevant research projects and discusses if and how the value of such services could be increased if they could be offered as e-Maritime services to the industry. Furthermore, two services have been selected and successfully implemented as pilot e-Maritime services. Based on this survey and the pilot implementations, it can be suggested that there are great potential for offering a number of existing and future services related to safety, security and environmental protection as e-Maritime services. However, standardisation of the framework and of specific maritime data types, messages and codes might be necessary to facilitate a development towards widespread adaptation of e-Maritime solutions.

  14. Toward a treaty on safety and cost-effectiveness of pharmaceuticals and medical devices: enhancing an endangered global public good

    Directory of Open Access Journals (Sweden)

    Faunce Thomas

    2006-03-01

    Full Text Available Abstract • Expert evaluations of the safety, efficacy and cost-effectiveness of pharmaceutical and medical devices, prior to marketing approval or reimbursement listing, collectively represent a globally important public good. The scientific processes involved play a major role in protecting the public from product risks such as unintended or adverse events, sub-standard production and unnecessary burdens on individual and governmental healthcare budgets. • Most States now have an increasing policy interest in this area, though institutional arrangements, particularly in the area of cost-effectiveness analysis of medical devices, are not uniformly advanced and are fragile in the face of opposing multinational industry pressure to recoup investment and maintain profit margins. • This paper examines the possibility, in this context, of States commencing negotiations toward bilateral trade agreement provisions, and ultimately perhaps a multilateral Treaty, on safety, efficacy and cost-effectiveness analysis of pharmaceuticals and medical devices. Such obligations may robustly facilitate a conceptually interlinked, but endangered, global public good, without compromising the capacity of intellectual property laws to facilitate local product innovations.

  15. Managing the Cost of Enhanced Oil Recovery Gérer le coût de la récupération assistée

    Directory of Open Access Journals (Sweden)

    Simandoux P.

    2006-11-01

    Full Text Available The drop in crude-oil prices has caused a worldwide slowing down of the growth of enhanced-recovery activities and a recentering on less costly processes. The technical costs of implementing such methods have diminished, mainly because of the decrease in the cost of services, but insufficiently to ensure the economic viability of many projects. Therefore, today even more than yesterday, it is of prime importance to search for all ways of reducing the cost of enhanced recovery. It is thus indispensable to improve our mastery of process, the knowledge and management of reservoirs, and to use the appropriate indicators to follow the evolution of costs. Likewise, synergisms resulting from the use of horizontal drain holes at the same time as steam or polymer flooding must be systematically sought for. Lastly, only sustained activity in the field of pilot projects can enable these goals to be reached. La baisse du prix du brut a provoqué au plan mondial un ralentissement de la croissance de l'activité de la récupération assistée et un recentrage sur les procédés les moins onéreux. Les coûts techniques de mise en oeuvre de ces méthodes ont diminué, essentiellement grâce à la baisse du coût des services, mais de façon insuffisante pour assurer la viabilité économique de nombreux projets. En conséquence, aujourd'hui encore plus qu'hier, il est de première importance de rechercher toutes les voies de réduction des coûts offertes par la récupération assistée. Dans ce sens, il est indispensable d'améliorer la maîtrise des procédés, la connaissance et la gestion des réservoirs, et de suivre avec des indicateurs appropriés l'évolution des coûts. De même, les synergies résultant de l'utilisation de drains horizontaux simultanément avec une injection de vapeur ou de polymères doivent être systématiquement recherchées. Enfin, seule une activité soutenue en terme de pilotes peut permettre d'atteindre ces objectifs.

  16. DOE handbook electrical safety

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-01-01

    Electrical Safety Handbook presents the Department of Energy (DOE) safety standards for DOE field offices or facilities involved in the use of electrical energy. It has been prepared to provide a uniform set of electrical safety guidance and information for DOE installations to effect a reduction or elimination of risks associated with the use of electrical energy. The objectives of this handbook are to enhance electrical safety awareness and mitigate electrical hazards to employees, the public, and the environment.

  17. Electrical safety guidelines

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Electrical Safety Guidelines prescribes the DOE safety standards for DOE field offices or facilities involved in the use of electrical energy. It has been prepared to provide a uniform set of electrical safety standards and guidance for DOE installations in order to affect a reduction or elimination of risks associated with the use of electrical energy. The objectives of these guidelines are to enhance electrical safety awareness and mitigate electrical hazards to employees, the public, and the environment.

  18. International conference on the strengthening of nuclear safety in Eastern Europe. Keynote papers. Regulatory aspects of NPP safety, status of safety improvements, status of safety analysis report

    International Nuclear Information System (INIS)

    The Objective of the Conference was to assess the past decade of nuclear safety efforts in countries operating WWER and RBMK nuclear reactors and to address remaining safety issues which require further work. A particular focus of the Conference was on international co-operation and assistance and where such efforts should be focused in the future. All Eastern European countries that operate RBMK or WWER reactors participated in the Conference, and presented papers on three key areas of nuclear safety: Regulatory Aspects of Nuclear Power Plant Safety; Status of Safety Improvements; and Status of Safety Analysis Reports. In addition, representatives from 18 additional countries that provide financial and/or technical assistance and co-operation in the area of WWER and RBMK safety offered the most extensive commentary. Key international (IAEA, World Association of Nuclear Operators, the Nuclear Energy Agency, the G-24 NUSAC, the European Commission, and the EBRD) organizations that provide nuclear safety assistance for WWER and RBMK reactors also made presentations. There is no question that considerable progress on nuclear safety has been made in Eastern Europe. Special mention should be made of successful efforts to strengthen the independence and technical competence of the nuclear regulatory authorities. Efforts should now concentrate on improving the depth and scope of the technical abilities of the regulatory authorities. More attention by governments is needed to ensure that the regulatory authorities have the financial resources and enforcement authority to fully execute their missions. In respect to the operators of the nuclear power plants, they have demonstrated clear progress in operational safety improvements. Significant additional efforts are required to maintain and enhance an effective safety culture. Design safety improvement programmes are in place in all countries. Implementation of these programmes has varied and is particularly affected by

  19. Transformational activity by top management for the enhancement of safety in a nuclear power plant in Japan

    International Nuclear Information System (INIS)

    Using Engestroem's activity theory, we investigated how company-wide transformational activity was initiated and how it has changed everyday activities in a nuclear power plant in Japan. We renamed 'learning activity' in the theory 'transformational activity' in this paper. It was defined as an activity that continues for a certain amount of period and transforms existing everyday organizational activities into new ones by changing the underlying premises of activities. We described a precise example of transformational activity we observed in our intensive field work in a large electric power company where the first fatal accident in the history of a nuclear power plant in Japan occurred in one plant several years ago. Using the model of activity theory, this transformational activity was depicted as following: the reform committee for maintenance work (subject of activity) acted on existing everyday activities for maintenance (object of activity) and transformed them into new ones (outcome of activity) with the use of requests submitted by subcontracted workers for improvement of working conditions and a budget to materialize them (mediating artifact of activity), in the collaboration with the top management who launched and persistently supported the reform committee, subcontracted workers responsible for the physical labor force in operational fields who actively submitted requests for improvement, and workers of the electric company who reviewed the requests and materialized most of them by a budgetary step (community member of activity and division of labor of activity), and with the shared awareness that any measures should be taken to actualize the lesson from the accident (rule of activity). Prior to the accident, safety was regarded as important as long as efficiency would not be sacrificed. Now, in the everyday activities achieved by the transformational activity, safety in operational fields is emphasized to the extent that anyone could not have

  20. SU-E-T-599: Patient Safety Enhancements Through a Study of R&V System Override Data

    International Nuclear Information System (INIS)

    Purpose: Record and verify (R&V) software systems include safety checks that compare actual machine parameters with prescribed values for a patient’s treatment, such as treatment couch position, linac, energy, and MUs. The therapist is warned of a mismatch with a pop-up and prompted to approve an override in order to continue without changes. Override approval is often legitimate, but the pop-up can also genuinely indicate a problem that would Result in the wrong treatment. When there are numerous pop-up warnings, human nature leads us to approve any override without careful reading, undermining the effectiveness of the safety mechanism. Methods: Override data was collected from our R&V system for all patients treated between October 8 and 29, 2012, on four linacs and entered into a spreadsheet. Additional data collected included treatment technique, disease site, immobilization, time, linac, and whether localization images were obtained. Data were analyzed using spreadsheet tools to reveal trends, patterns and associations that might suggest appropriate process changes that could decrease the total number of overrides. Results: 76 out of 113 patients had overrides. Out of the 944 treatments, 599 override items were generated. The majority were due to couch positions. 74 of the 84 overrides on a linac equipped with a 6D couch were due to the use of the rotational corrections and the fact that the 6D couch control does not communicate with the R&V system; translations required to rotate the couch appear to the R&V system as translations outside the tolerance range. Conclusion: Many findings were interesting but did not suggest a process change. Proposed process changes include creating site-specific instead of just technique-specific tolerance tables for couch shifts. Proposed improvements to the vendor are to facilitate direct communication between the 6D couch and the R&V system to eliminate those override warnings related to lack of communication

  1. Pacific Northwest Laboratory annual report for 1979 to the DOE Assistant Secretary for Environment. Part 5. Environmental assessment, control, health, and safety

    Energy Technology Data Exchange (ETDEWEB)

    Baalman, R.W.; Dotson, C.W. (eds.)

    1980-02-01

    Part 5 of the 1979 Annual Report to the Department of Energy Assistant Secretary for the Environment presents Pacific Northwest Laboratory's progress on work performed for the Office of Technology Impacts, the Office of Environmental Compliance and Overview, and the Office of Health and Environmental Research. The report is in four sections, corresponding to the program elements: technology impacts, environmental control engineering, operational and environmental compliance, and human health studies. In each section, articles describe progress made during FY 1979 on individual projects.

  2. A cascade signal amplification strategy for surface enhanced Raman spectroscopy detection of thrombin based on DNAzyme assistant DNA recycling and rolling circle amplification.

    Science.gov (United States)

    Gao, Fenglei; Du, Lili; Tang, Daoquan; Lu, Yao; Zhang, Yanzhuo; Zhang, Lixian

    2015-04-15

    A sensitive protocol for surface enhanced Raman spectroscopy (SERS) detection of thrombin is designed with R6G-Ag NPs as a signal tag by combining DNAzyme assistant DNA recycling and rolling circle amplification (RCA). Molecular beacon (MB) as recognition probe immobilizes on the glass slides and performs the amplification procedure. After thrombin-induced structure-switching DNA hairpins of probe 1, the DNAzyme is liberated from the caged structure, which hybridizes with the MB for cleavage of the MB in the presence of cofactor Zn(2+) and initiates the DNA recycling process, leading to the cleavage of a large number of MB and the generation of numerous primers for triggering RCA reaction. The long amplified RCA product which contained hundreds of tandem-repeat sequences, which can bind with oligonucleotide functionalized Ag NPs reporters. The attached signal tags can be easily read out by SERS. Because of the cascade signal amplification, these newly designed protocols provides a sensitive SERS detection of thrombin down to the femolar level (2.3fM) with a linear range of 5 orders of magnitude (from 10(-14) to 10(-9)M) and have high selectivity toward its target protein. The proposed method is expected to be a good clinical tool for the diagnosis of a thrombotic disease.

  3. Biofunction-assisted DNA detection through RNase H-enhanced 3' processing of a premature tRNA probe in a wheat germ extract.

    Science.gov (United States)

    Ogawa, Atsushi; Tabuchi, Junichiro; Doi, Yasunori; Takamatsu, Masashi

    2016-08-01

    We have developed a novel type of biofunction-assisted, signal-turn-on sensor for simply and homogenously detecting DNA. This sensor system is composed of two types of in vitro-transcribed label-free RNAs (a 3' premature amber suppressor tRNA probe and an amber-mutated mRNA encoding a reporter protein), RNase H, and a wheat germ extract (WGE). A target DNA induces the 3' end maturation of the tRNA probe, which is enhanced by RNase H and leads to the expression of a full-length reporter protein through amber suppression in WGE, while there is almost no expression without the target due to the inactivity of the premature probe. Therefore, the target can be readily detected with the activity of the translated reporter. The catalytic reuse of the target with the help of RNase H in addition to various bioprocesses in WGE enables this sensor system to exhibit relatively high selectivity and sensitivity. PMID:27289318

  4. Cryogenic safety organisation at CERN

    CERN Document Server

    CERN. Geneva

    2016-01-01

    With Safety being a top priority of CERN’s general policy, the Organisation defines and implements a Policy that sets out the general principles governing Safety at CERN. To the end of the attainment of said Safety objectives, the organic units (owners/users of the equipment) are assigned the responsibility for the implementation of the CERN Safety Policy at all levels of the organization, whereas the Health and Safety and Environmental Protection Unit (HSE) has the role of providing assistance for the implementation of the Safety Policy, and a monitoring role related to the implementation of continuous improvement of Safety, compliance with the Safety Rules and the handling of emergency situations. This talk will elaborate on the roles, responsibilities and organisational structure of the different stakeholders within the Organization with regards to Safety, and in particular to cryogenic safety. The roles of actors of particular importance such as the Cryogenic Safety Officers (CSOs) and the Cryogenic Sa...

  5. Safety of meglumine gadoterate (Gd-DOTA)-enhanced MRI compared to unenhanced MRI in patients with chronic kidney disease (RESCUE study)

    Energy Technology Data Exchange (ETDEWEB)

    Deray, Gilbert [Pitie Salpetriere Hospital, Department of Nephrology, Paris cedex 13 (France); Rouviere, Olivier [Hopital E. Herriot, Universite de Lyon, Hospices Civils de Lyon, Department of Urinary and Vascular Imaging, Lyon (France); Universite Lyon 1, faculte de medecine Lyon Est, Lyon (France); Bacigalupo, Lorenzo [E.O. Ospedali Galliera, Radiology Department, Genova (Italy); Maes, Bart [Heilig Hartziekenhuis Roeselare, Department of Nephrology, Roeselare (Belgium); Hannedouche, Thierry [University Hospitals, Department of Nephrology, Strasbourg (France); Vrtovsnik, Francois [Bichat Hospital, Department of Nephrology, Paris (France); Rigothier, Claire [Pellegrin Hospital, Department of Nephrology Transplantation Dialysis, Bordeaux (France); Billiouw, Jean-Marie [Onze Lieve Vrouw Ziekenhuis, Department of Nephrology, Aalst (Belgium); Campioni, Paolo [Azienda Ospedaliero-Universitaria Sant' Anna, Ferrara (Italy); Ferreiros, Joaquin [Hospital Clinico de San Carlos, Servicio de Radiodiagnostico, Madrid (Spain); Devos, Daniel [Gent University Hospital, Department of Radiology, Gent (Belgium); Alison, Daniel [Trousseau Hospital, Department of Radiology, Tours (France); Glowacki, Francois [University Hospitals, Department of Nephrology, Lille (France); Boffa, Jean-Jacques [Tenon Hospital, Department of Nephrology and Dialysis, Paris (France); Marti-Bonmati, Luis [University of Valencia, Department of Radiology, Valencia (Spain)

    2013-05-15

    To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high-risk patients. Patients with chronic kidney disease (CKD) scheduled for MRI procedures were screened. The primary endpoint was the percentage of patients with an elevation of serum creatinine levels, measured 72 {+-} 24 h after the MRI procedure, by at least 25 % or 44.2 {mu}mol/l (0.5 mg/dl) from baseline. A non-inferiority margin of the between-group difference was set at -15 % for statistical analysis of the primary endpoint. Main secondary endpoints were the variation in serum creatinine and eGFR values between baseline and 72 {+-} 24 h after MRI and the percentage of patients with a decrease in eGFR of at least 25 % from baseline. Patients were screened for signs of nephrogenic systemic fibrosis (NSF) at 3-month follow-up. Among the 114 evaluable patients, one (1.4 %) in the Gd-DOTA-MRI group and none in the control group met the criteria of the primary endpoint [{Delta} = -1.4 %, 95%CI = (-7.9 %; 6.7 %)]. Non-inferiority was therefore demonstrated (P = 0.001). No clinically significant differences were observed between groups for the secondary endpoints. No serious safety events (including NSF) were noted. Meglumine gadoterate did not affect renal function and was a safe contrast agent in patients with CKD. (orig.)

  6. Challenges Faced by Regulators and Technical, Scientific and Support Organizations (TSOs) in Enhancing Nuclear Safety and Security

    International Nuclear Information System (INIS)

    Renewed interest in new reactor build programmes, not only in countries with already established nuclear programmes but also in many other countries with limited or no workforce experienced in the design, licensing, construction and operation of nuclear power plants, has resulted in a need for technical, scientific and support organizations (TSOs) to support regulatory bodies in carrying out their mandated responsibilities. The primary function of a regulatory body, such as the Federal Authority for Nuclear Regulation (FANR) in the United Arab Emirates (UAE), is to regulate the safe use of nuclear facilities and radioactive material for peaceful civilian purposes. In so doing, the regulatory body needs to provide a clear and focused approach to: safety, security and safeguards for licensing; inspection and enforcement of reactor design; construction; commissioning; operation; decommissioning; nuclear waste management activities; and the use, possession or transfer of special nuclear materials and activities within the country. Accomplishing this goal requires a highly educated, multidisciplinary, diverse workforce with significant work experience. Recognizing that it takes several decades and a lot of resources to achieve self-sufficiency, many countries, particularly emergent nuclear countries, would have to rely on TSOs to start their programmes and to carry out their oversight responsibilities. Towards that end, FANR is working closely with international counterparts, the International Atomic Energy Agency and TSOs to exchange information, expertise, industry experience and ongoing research to ensure that high levels of safety, security and safeguards are established and maintained in reactor design and operation throughout the life of the facility, and that special nuclear material within the UAE is properly documented and controlled, is not stolen, lost or diverted to any illicit or non-peaceful activities, and does not pose unreasonable radiological risk due

  7. Review of the safety, efficacy, costs and patient acceptability of recombinant follicle-stimulating hormone for injection in assisting ovulation induction in infertile women

    Directory of Open Access Journals (Sweden)

    Marleen Nahuis

    2009-11-01

    Full Text Available Marleen Nahuis1,2,3, Fulco van der Veen1, Jur Oosterhuis2, Ben Willem Mol1, Peter Hompes3, Madelon van Wely11Center for Reproductive Medicine, Department of Obstetrics and Gynaecology (H4-205, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; 2Department of Obstetrics and Gynaecology, Medisch Spectrum Twente, Enschede, The Netherlands; 3Department of Obstetrics and Gynaecology, Free Medical University, Amsterdam, The NetherlandsAbstract: Anovulation is a common cause of female subfertility. Treatment of anovulation is aimed at induction of ovulation. In women with clomiphene-citrate resistant WHO group II anovulation, one of the treatment options is ovulation induction with exogenous follicle-stimulating hormone (FSH or follitropin. FSH is derived from urine or is produced as recombinant FSH. Two forms of recombinant FSH are available – follitropin alpha and follitropin beta. To evaluate the efficacy, safety, costs and acceptability of recombinant FSH, we performed a review to compare recombinant FSH with urinary-derived FSH products. Follitropin alpha, beta and urinary FSH products appeared to be equally effective in terms of pregnancy rates. Patient safety was also found to be comparable, as the incidence of side effects including multiple pregnancies was similar for all FSH products. In practice follitropin alpha and beta may be more convenient to use due to the ease of self-administration, but they are also more expensive than the urinary products.Keywords: follitropin apha, follitropin beta, urinary gonadotropins, polycystic ovary syndrome

  8. The Unsuspected Roles of Chemistry in Nuclear Power Plants: Special Chemical Technologies for Enhanced Safety and Increased Performance

    Energy Technology Data Exchange (ETDEWEB)

    Sempere Belda, Luis [AREVA NP GmbH, An AREVA and SIEMENS Company, P.O. Box 1109, Erlangen (Germany)

    2008-07-01

    The plant's chemists main responsibility is the establishment and monitoring of an adequate water chemistry to minimize corrosion and in PWRs, to control the neutron flux. But this is by no means the only way in which chemical applications contribute to the performance and safety of a NPP during its entire life: The use of special coatings and treatment protects the plant's components from aggressive environmental conditions. The chemical scale removal in steam generators improves the power output of aging plants, helping even to achieve permissions for NPP life extension. The use of special adhesives can replace welding in complicated or high-dose areas, even underwater. And chemical decontamination is used to remove activity from the components of the primary circuit prior to maintenance or replacement works in order to decrease the radiation exposure of the plant's personnel, employing revolutionary methods of waste minimization to limit the amount of generated radioactive waste to a minimum. The AREVA Group, in its pursue of excellence in all stages of the nuclear cycle, has devoted years of research and development to be able to provide the most advanced technological solutions in this field. The awareness of the existing possibilities will help present and future nuclear professionals, chemists and non-chemists alike, to benefit from the years of experience and continuous development in chemical technologies at the service of the nuclear industry. (authors)

  9. The use of matrix coating assisted by an electric field (MCAEF) to enhance mass spectrometric imaging of human prostate cancer biomarkers.

    Science.gov (United States)

    Wang, Xiaodong; Han, Jun; Hardie, Darryl B; Yang, Juncong; Borchers, Christoph H

    2016-01-01

    In this work, we combined a newly developed matrix coating technique - matrix coating assisted by an electric field (MCAEF) and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) to enhance the imaging of peptides and proteins in tissue specimens of human prostate cancer. MCAEF increased the signal-to-noise ratios of the detected proteins by a factor of 2 to 5, and 232 signals were detected within the m/z 3500-37500 mass range on a time-of-flight mass spectrometer and with the sinapinic acid MALDI matrix. Among these species, three proteins (S100-A9, S100-A10, and S100-A12) were only observed in the cancerous cell region and 14 proteins, including a fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2, a fragment of cAMP-regulated phosphoprotein 19, 3 apolipoproteins (C-I, A-I, and A-II), 2 S100 proteins (A6 and A8), β-microseminoprotein, tumor protein D52, α-1-acid glycoprotein 1, heat shock protein β-1, prostate-specific antigen, and 2 unidentified large peptides at m/z 5002.2 and 6704.2, showed significantly differential distributions at the p < 0.05 (t-test) level between the cancerous and the noncancerous regions of the tissue. Among these 17 species, the distributions of apolipoprotein C-I, S100-A6, and S100-A8 were verified by immunohistological staining. In summary, this study resulted in the imaging of the largest group of proteins in prostate cancer tissues by MALDI-MS reported thus far, and is the first to show a correlation between S100 proteins and prostate cancer in a MS imaging study. The successful imaging of the three proteins only found in the cancerous tissues, as well as those showing differential expressions demonstrated the potential of MCAEF-MALDI/MS for the in situ detection of potential cancer biomarkers. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Enhancing the stability and ecological safety of mass-reared transgenic strains for field release by redundant conditional lethality systems.

    Science.gov (United States)

    Handler, Alfred M

    2016-04-01

    The genetic manipulation of agriculturally important insects now allows the development of genetic sexing and male sterility systems for more highly efficient biologically-based population control programs, most notably the Sterile Insect Technique (SIT), for both plant and animal insect pests. Tetracycline-suppressible (Tet-off) conditional lethal systems may function together so that transgenic strains will be viable and fertile on a tetracycline-containing diet, but female-lethal and male sterile in tetracycline-free conditions. This would allow their most efficacious use in a unified system for sterile male-only production for SIT. A critical consideration for the field release of such transgenic insect strains, however, is a determination of the frequency and genetic basis of lethality revertant survival. This will provide knowledge essential to evaluating the genetic stability of the lethality system, its environmental safety, and provide the basis for modifications ensuring optimal efficacy. For Tet-off lethal survival determinations, development of large-scale screening protocols should also allow the testing of these modifications, and test the ability of other conditional lethal systems to fully suppress propagation of rare Tet-off survivors. If a dominant temperature sensitive (DTS) pupal lethality system proves efficient for secondary lethality in Drosophila, it may provide the safeguard needed to support the release of sexing/sterility strains, and potentially, the release of unisex lethality strains as a form of genetic male sterility. Should the DTS Prosβ2(1) mutation prove effective for redundant lethality, its high level of structural and functional conservation should allow host-specific cognates to be created for a wide range of insect species. PMID:26097098

  11. Journey of Mesenchymal Stem Cells for Homing: Strategies to Enhance Efficacy and Safety of Stem Cell Therapy

    Directory of Open Access Journals (Sweden)

    Sung Keun Kang

    2012-01-01

    Full Text Available Human mesenchymal stem cells (MSCs communicate with other cells in the human body and appear to “home” to areas of injury in response to signals of cellular damage, known as homing signals. This review of the state of current research on homing of MSCs suggests that favorable cellular conditions and the in vivo environment facilitate and are required for the migration of MSCs to the site of insult or injury in vivo. We review the current understanding of MSC migration and discuss strategies for enhancing both the environmental and cellular conditions that give rise to effective homing of MSCs. This may allow MSCs to quickly find and migrate to injured tissues, where they may best exert clinical benefits resulting from improved homing and the presence of increased numbers of MSCs.

  12. Procedures for self-assessment of operational safety

    International Nuclear Information System (INIS)

    Self-assessment processes have been continuously developed by nuclear organizations, including nuclear power plants. Currently, the nuclear industry and governmental organizations are showing an increasing interest in the implementation of this process as an effective way for improving safety performance. Self-assessment involves the use of different types of tools and mechanisms to assist the organizations in assessing their own safety performance against given standards. This helps to enhance the understanding of the need for improvements, the feeling of ownership in achieving them and and the safety culture as a whole. The concepts developed in this report present the basic approach to self-assessment taking into consideration experience gained during Operational Safety Review Team (OSART) missions, from organizations and utilities which have successfully implemented parts of a self-assessment programme and from meetings organized to discuss the subject

  13. Environmental and source monitoring for purposes of radiation protection. Safety guide

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the Contracting Parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education. The

  14. Safety advice sheets

    CERN Multimedia

    HSE Unit

    2013-01-01

    You never know when you might be faced with questions such as: when/how should I dispose of a gas canister? Where can I find an inspection report? How should I handle/store/dispose of a chemical substance…?   The SI section of the DGS/SEE Group is primarily responsible for safety inspections, evaluating the safety conditions of equipment items, premises and facilities. On top of this core task, it also regularly issues “Safety Advice Sheets” on various topics, designed to be of assistance to users but also to recall and reinforce safety rules and procedures. These clear and concise sheets, complete with illustrations, are easy to display in the appropriate areas. The following safety advice sheets have been issued so far: Other sheets will be published shortly. Suggestions are welcome and should be sent to the SI section of the DGS/SEE Group. Please send enquiries to general-safety-visits.service@cern.ch.

  15. Graphene flakes enhance the detection of TiO2-enriched catechins by SALDI-MS after microwave-assisted enrichment.

    Science.gov (United States)

    Juang, Yu-Min; Chien, Han-Ju; Chen, Chao-Jung; Lai, Chien-Chen

    2016-06-01

    In this study, we describe a novel method for the rapid detection of catechins in tea leaves using surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). The method involves incubating catechins in a mixture of titanium dioxide (TiO2) nanoparticles and graphene flakes (GF) and then subjecting the mixture to microwave irradiation to facilitate the enrichment of analytes. In this approach, TiO2 nanoparticles serve as probes to enrich catechins while GF serve to increase the desorption/ionization efficiency. The use of the TiO2-GF mixture as matrix provides a number of advantages over TiO2 nanoparticles alone, including higher desorption/ionization efficiency, enhanced analyte enrichment and reduced run time (less 10min). We demonstrate that the addition of GF to nanoparticles of TiO2 improves the detection of catechins by SALDI-MS. At a signal-to-noise ratio of 3, the limits of detection were 0.04pmole for (+)-catechin (C), 0.17pmole for (-)-epigallocatechin (EGC), 0.35pmole for (-)-epicatechin gallate (ECG), and 0.50pmole for (-)-epigallocatechin gallate (EGCG). This method was further applied to determine the catechin content in several tea samples and the results showed good shot-to-shot and sample-to-sample reproducibility (less than 10% and 13%, respectively) as well as good quantitative linearity for the four analytes (R(2)>0.995). The precision calculated as percent relative standard derivation (%RSD), ranged from 3.6% to 12.4%. Overall, we show that this method is a sensitive, simple and high-throughput technique for the detection of catechins in tea. PMID:27130126

  16. Self-assessment of operational safety for nuclear power plants

    International Nuclear Information System (INIS)

    Self-assessment processes have been continuously developed by nuclear organizations, including nuclear power plants. Currently, the nuclear industry and governmental organizations are showing an increasing interest in the implementation of this process as an effective way for improving safety performance. Self-assessment involves the use of different types of tools and mechanisms to assist the organizations in assessing their own safety performance against given standards. This helps to enhance the understanding of the need for improvements, the feeling of ownership in achieving them and the safety culture as a whole. Although the primary beneficiaries of the self-assessment process are the plant and operating organization, the results of the self-assessments are also used, for example, to increase the confidence of the regulator in the safe operation of an installation, and could be used to assist in meeting obligations under the Convention on Nuclear Safety. Such considerations influence the form of assessment, as well as the type and detail of the results. The concepts developed in this report present the basic approach to self-assessment, taking into consideration experience gained during Operational Safety Review Team (OSART) missions, from organizations and utilities which have successfully implemented parts of a self-assessment programme and from meetings organized to discuss the subject. This report will be used in IAEA sponsored workshops and seminars on operational safety that include the topic of self-assessment

  17. Radiation safety audit system - safety perspectives

    International Nuclear Information System (INIS)

    In 2005 Safety and Health at the University of Western Australia (UWA) implemented a system of Radiation Safety Audits. The system was implemented to ensure complete audits were carried out annually for each section of the University with radiation safety issues. The audits cover those aspects of radiation safety regulated in the Radiation Safety Act of Western Australia and include high powered lasers, UV emitting devices, radioactive materials, x-ray machines. In relation to these there are regulated considerations for equipment registration, location of use and storage registration, licensing of individual to use radiation, training, documentation, working rules, personal monitoring, calibrations and supervision. Within the University there are University systems to control materials and equipment coming onto campus, risk assessment protocols required for each new project or type of work, local permits and waste disposal. UWA Safety and Health have an active role in delivering control of radiation safety and ensuring that safety systems are appropriate relevant and used in an immediate and useful manner. Safety and Health has importantly built a network of key people on campus, made sure they are assisted, valued and that the systems are seen as a way to improve efficiency in delivering real, relevant and useful radiation safety outcomes. The systems include uniform documentation across campus, clear expectations and an ongoing interest from Safety and Health to ensure the systems remain alive. This has allowed the audits to become efficient and effective both for the sections involved but also for Safety and health in its recording systems and improvement follow up process.

  18. Using Calculator-Assisted Instruction to Enhance Low-Achievers in Learning Number Sense: A Case Study of Two Fifth Graders in Taiwan

    Science.gov (United States)

    Yang, Der-Ching; Lin, Yung-Chi

    2015-01-01

    The purpose of this study was to use calculator-assisted instruction to help two fifth-grade low-achievers learn number sense. The research process includes three stages: (1) pre-test interview to detect what kinds of number sense the students did not have; (2) calculator-assisted instruction to help them develop number sense; and (3) post-test…

  19. Comparative safety and effectiveness of cognitive enhancers for Alzheimer's dementia: protocol for a systematic review and individual patient data network meta-analysis

    Science.gov (United States)

    Veroniki, Areti Angeliki; Straus, Sharon E; Ashoor, Huda M; Hamid, Jemila S; Hemmelgarn, Brenda R; Holroyd-Leduc, Jayna; Majumdar, Sumit R; McAuley, Glenn; Tricco, Andrea C

    2016-01-01

    Introduction Alzheimer's dementia (AD) is the most common cause of dementia, and several organisations, such as the National Institute for Health and Care Excellence, suggest that management of patients with AD should be tailored to their needs. To date, little research has been conducted on the treatment effect in different subgroups of patients with AD. The aim of this study is to examine the comparative effectiveness and safety of cognitive enhancers for different patient characteristics. Methods and analysis We will update our previous literature search from January 2015 forward, using the same terms and electronic databases (eg, MEDLINE) from our previous review. We will additionally search grey literature and scan the reference lists of the included studies. Randomised clinical trials of any duration conducted at any time comparing cognitive enhancers alone or in any combination against other cognitive enhancers, or placebo in adults with AD will be eligible. The outcomes of interest are cognition according to the Mini-Mental State Examination, and overall serious adverse events. For each outcome and treatment comparison, we will perform a Bayesian hierarchical random-effects meta-analysis combining the individual patient data (IPD) from each eligible study. If the identified treatment comparisons form a connected network diagram, we will perform an IPD network meta-analysis (NMA) to estimate subgroup effects for patients with different characteristics, such as AD severity and sex. We will combine aggregated data from studies that we will not be able to obtain IPD, with the IPD provided by the original authors, in a single model. We will use the PRISMA-IPD and PRISMA-NMA statements to report our findings. Ethics and dissemination The findings of this study will be of interest to stakeholders, including decision makers, guideline developers, clinicians, methodologists and patients, and they will help to improve guidelines for the management of patients with AD

  20. Pathogen safety of intravenous Rh immunoglobulin liquid and other immune globulin products: enhanced nanofiltration and manufacturing process overview.

    Science.gov (United States)

    Soluk, Lori; Price, Hugh; Sinclair, Chris; Atalla-Mikhail, Dina; Genereux, Maurice

    2008-01-01

    Plasma products for therapeutic use pose specific challenges in manufacturing to ensure products maintain biologic activity and are safe with respect to contamination and transmission of disease-causing agents. Various processes have demonstrated effectiveness in eliminating, reducing, or inactivating viral contaminants. Recently, the possibility of transmitting variant Creutzfeld-Jakob disease (vCJD) or transmissible spongiform encephalopathies (TSE) through blood-based products has become a concern. The present study involves the validation of a hyperimmune immunoglobulin manufacturing process incorporating a nanofiltration step with a nominal pore size of 20 nm for removal of viral contaminants and other adventitious agents. Processing intermediates during the manufacture of IV Rh IgG (WinRho SDF/WinRho SDF Liquid, Cangene Corporation, Manitoba, Canada) were spiked with model viruses and processed in scaled-down procedures to validate the viral reduction capacity of each step. Anion-exchange chromatography and solvent/detergent steps are known to contribute to virus removal and inactivation. The Planova 20 N nanofiltration step was effective in reducing model viruses representing a wide range of viral morphologies with varying degrees of resistance to physicochemical inactivation. All in-process and final batch testing met current standards for production of IV Rh IgG manufactured with the previously licensed filter, which had a larger nominal pore size of 35 nm. The manufacturing process, employing a Planova 35 N filtration step, has been proactively improved by the change to a smaller-pore 20 N filter. Replacement of the 35 N filter with the 20 N filter produces a similar product while enhancing the capability for removal of smaller viruses and prions. PMID:18806519

  1. New technologies to enhance quality and safety of table eggs: ultra-violet treatment and modified atmosphere packaging

    Directory of Open Access Journals (Sweden)

    Frédérique Pasquali

    2014-12-01

    Full Text Available In the present study the effect of ultra-violet (UV treatment alone and in combination with 100% CO2 modified atmosphere packaging (MAP was evaluated both on the survival of naturally occurring bacteria, as well as on quality parameters of table eggs during 28 days of storage at 21°C. Table eggs were collected from the conveyor belt after the UV module, and placed on carton trays. A representative number of carton trays were packed in a high barrier multilayer pouch filled with 100% CO2. All eggs were stored at 21°C and analysed at 0, 1, 7, 14, 21 and 28 days of storage. Eggs not treated with UV and not packed were also included. On the eggshells total colony count, total coliforms and faecal coliforms counts, as well as the detection of Salmonella spp. were investigated. Moreover, chemical-functional parameters such as weight loss, albumen pH and Haugh Unit (HU were evaluated. The total colony count on UV treated table eggs was approximately 1 log10 CFU/g lower than untreated eggs (2.27 vs 3.29 log10 CFU/g. During storage, CO2 packed eggs maintained the initial values of HU, whereas the albumen pH decreased up to 1.5-2 points in comparison to unpacked eggs. The UV treatment was effective in reducing the total colony count on the surface of table eggs. MAP showed a great potential in maintaining/enhance the technological properties of egg constituents (higher foam stability of the albumen for meringue preparation without significantly impacting on the microbial load of table eggs.

  2. Immune enhancement by novel vaccine adjuvants in autoimmune-prone NZB/W F1 mice: relative efficacy and safety

    Directory of Open Access Journals (Sweden)

    Ghosh Swapan K

    2011-10-01

    Full Text Available Abstract Background Vaccines have profoundly impacted global health although concerns persist about their potential role in autoimmune or other adverse reactions. To address these concerns, vaccine components like immunogens and adjuvants require critical evaluation not only in healthy subjects but also in those genetically averse to vaccine constituents. Evaluation in autoimmune-prone animal models of adjuvants is therefore important in vaccine development. The objective here was to assess the effectiveness of experimental adjuvants: two phytol-derived immunostimulants PHIS-01 (phytanol and PHIS-03 (phytanyl mannose, and a new commercial adjuvant from porcine small intestinal submucosa (SIS-H, relative to a standard adjuvant alum. Phytol derivatives are hydrophobic, oil-in water diterpenoids, while alum is hydrophilic, and SIS is essentially a biodegradable and collagenous protein cocktail derived from extracellular matrices. Results We studied phthalate -specific and cross-reactive anti-DNA antibody responses, and parameters associated with the onset of autoimmune disorders. We determined antibody isotype and cytokine/chemokine milieu induced by the above experimental adjuvants relative to alum. Our results indicated that the phytol-derived adjuvant PHIS-01 exceeded alum in enhancing anti-phthalate antibody without much cross reactivity with ds-DNA. Relatively, SIS and PHIS-03 proved less robust, but they were also less inflammatory. Interestingly, these adjuvants facilitated isotype switching of anti-hapten, but not of anti-DNA response. The current study reaffirms our earlier reports on adjuvanticity of phytol compounds and SIS-H in non autoimmune-prone BALB/c and C57BL/6 mice. These adjuvants are as effective as alum also in autoimmune-prone NZB/WF1 mice, and they have little deleterious effects. Conclusion Although all adjuvants tested impacted cytokine/chemokine milieu in favor of Th1/Th2 balance, the phytol compounds fared better in

  3. Enhancing SafEty throughout conStruction uSing BiM/VDc%利用BIM与VDC加强施工安全

    Institute of Scientific and Technical Information of China (English)

    卡尔拉·洛佩兹·德普尔托; 卡洛琳娜·M·克莱温格尔

    2012-01-01

      Construction jobsites are some of the most dangerous workplaces. According to the Bureau of Labor, in 2008 1005 fatalities resulted from construction accidents, and cost industry approximately$11.5 bil ion annual y. Many construction accidents could be avoided through better engineering and administrative controls, and improved safety training. 3D visualization and analyses are situated to play a critical role in enhancing safety. This paper discusses specific examples where BIM-enabled safety controls can be used to detect and alert designers and contractors to potential project hazards. If hazards are identified through simulation during the design phase, elimination and substitution of hazards may be substantial y less inexpensive and easier to implement. This paper discusses the use of BIM to enhance safety for construction workers, building users during renovations/expansions and building end-users. Using specific real-world examples this paper demostrates ways that BIM can be used to foresee potential construction hazards and motivates and informs future tool and process development.%  施工现场是最危险的一类工作场所。据美国劳工统计局统计,2008年,工程事故已导致1005人死亡,每年耗资约115亿美元。事实上,如果有更完善的工程与行政管控和施工安全培训,很多工程事故是可以避免的。三维可视化和分析在增强施工安全方面起着重要的作用。本文主要讨论了利用BIM支持的安全控制措施,监控潜在的工程危险,并列举了用以及时提醒设计人员和施工人员的实例。如果在设计阶段即可通过模拟发现潜在风险,那将会极大地降低解决风险或避免风险的成本,并且能够更容易地实施解决方案。本文讨论了BIM对项目改扩建期间加强施工人员、建筑物使用者以及最终用户等群体的安全问题所起到的积极作用。本文将采用实例来讨论利用BIM预测潜在

  4. Nitrite-triggered surface plasmon-assisted catalytic conversion of p-aminothiophenol to p,p'-dimercaptoazobenzene on gold nanoparticle: surface-enhanced Raman scattering investigation and potential for nitrite detection.

    Science.gov (United States)

    Liu, Xiangjiang; Tang, Longhua; Niessner, Reinhard; Ying, Yibin; Haisch, Christoph

    2015-01-01

    The stunning large enhancement factor (∼10(8)) of the surface-enhanced Raman scattering (SERS) effect leads people to wonder about the underlying enhancement mechanisms of the effect. But, a strong evidence of the existence of one commonly accepted mechanism (chemical enhancement), the origin of the symbolic "b2" bands (ca. 1140,1390, 1432 cm(-1)) of p-aminothiophenol (PATP), was recently found to be a false explanation, which were actually arisen from the product of a surface plasmon-assisted coupling reaction of PATP, p,p'-dimercaptoazobenzene (DMAB). However, the debate is far from over, especially because the mechanism of the above reaction has not been fully understood yet. In this paper, we for the first time report a new surface plasmon-assisted catalytic conversion of PATP to DMAB that NO2(-) ions can trigger the formation of DMAB on gold nanoparticles (GNPs) suspension under light illumination. The mechanism of the conversion is also discussed. All relevant data suggest the nitrite-triggered conversion of PATP to DMAB on GNPs is a surface plasmon-assisted oxidation reaction, involving transfer of multiple electrons from PATP to NO2(-) (electron acceptors) and protons, leading to the formation of DMAB. The proposed mechanisms may also help to understand the unclear surface plasmon-assisted catalytic coupling of PATP on the SERS substrates. Furthermore, inspired by the high selectivity of the above nitrite-triggered catalysis reaction, a simple and fast nitrite screening method was also developed, exhibiting good sensitivity. Considering other advantages of the assay, such as rapidness, simplicity of the detection procedures, and requirement of no sample pretreatment, it is a promising method for on-site fast screening or point-of-care application. PMID:25437255

  5. Building an immune-mediated coagulopathy consensus: early recognition and evaluation to enhance post-surgical patient safety

    Directory of Open Access Journals (Sweden)

    Voils Stacy A

    2009-05-01

    Full Text Available Abstract Topical hemostats, fibrin sealants, and surgical adhesives are regularly used in a variety of surgical procedures involving multiple disciplines. Generally, these adjuncts to surgical hemostasis are valuable means for improving wound visualization, reducing blood loss or adding tissue adherence; however, some of these agents are responsible for under-recognized adverse reactions and outcomes. Bovine thrombin, for example, is a topical hemostat with a long history of clinical application that is widely used alone or in combination with other hemostatic agents. Hematologists and coagulation experts are aware that these agents can lead to development of an immune-mediated coagulopathy (IMC. A paucity of data on the incidence of IMC contributes to under-recognition and leaves many surgeons unaware that this clinical entity, originating from normal immune responses to foreign antigen exposure, requires enhanced post-operative vigilance and judicious clinical judgment to achieve best outcomes. Postoperative bleeding may result from issues such as loosened ties or clips or the occurrence of a coagulopathy due to hemodilution, vitamin K deficiency, disseminated intravascular coagulation (DIC or post-transfusion, post-shock coagulopathic states. Other causes, such as liver disease, may be ruled out by a careful patient history and common pre-operative liver function tests. Less common are coagulopathies secondary to pathologic immune responses. Such coagulopathies include those that may result from inherent patient problems such as patients with an immune dysfunction related to systemic lupus erythrematosus (SLE or lymphoma that can invoke antibodies against native coagulation factors. Medical interventions may also provoke antibody formation in the form of self-directed anti-coagulation factor antibodies, that result in problematic bleeding; it is these iatrogenic post-operative coagulopathies, including those associated with bovine thrombin

  6. MRI active guidewire with an embedded temperature probe and providing a distinct tip signal to enhance clinical safety

    Directory of Open Access Journals (Sweden)

    Sonmez Merdim

    2012-06-01

    Full Text Available Abstract Background The field of interventional cardiovascular MRI is hampered by the unavailability of active guidewires that are both safe and conspicuous. Heating of conductive guidewires is difficult to predict in vivo and disruptive to measure using external probes. We describe a clinical-grade 0.035” (0.89 mm guidewire for MRI right and left heart catheterization at 1.5 T that has an internal probe to monitor temperature in real-time, and that has both tip and shaft visibility as well as suitable flexibility. Methods The design has an internal fiberoptic temperature probe, as well as a distal solenoid to enhance tip visibility on a loopless antenna. We tested different tip-solenoid configurations to balance heating and signal profiles. We tested mechanical performance in vitro and in vivo in comparison with a popular clinical nitinol guidewire. Results The solenoid displaced the point of maximal heating (“hot spot” from the tip to a more proximal location where it can be measured without impairing guidewire flexion. Probe pullback allowed creation of lengthwise guidewire temperature maps that allowed rapid evaluation of design prototypes. Distal-only solenoid attachment offered the best compromise between tip visibility and heating among design candidates. When fixed at the hot spot, the internal probe consistently reflected the maximum temperature compared external probes. Real-time temperature monitoring was performed during porcine left heart catheterization. Heating was negligible using normal operating parameters (flip angle, 45°; SAR, 1.01 W/kg; the temperature increased by 4.2°C only during high RF power mode (flip angle, 90°; SAR, 3.96 W/kg and only when the guidewire was isolated from blood cooling effects by an introducer sheath. The tip flexibility and in vivo performance of the final guidewire design were similar to a popular commercial guidewire. Conclusions We integrated a fiberoptic temperature probe inside

  7. Assisted Living

    Science.gov (United States)

    ... overwhelming majority of residents are female. Assisted Living Philosophy The philosophy of assisted living is to provide personalized, resident ... loved ones to learn about the care provider philosophy . Freedom of Choice The most progressive state regulations ...

  8. Assistive Technology

    Science.gov (United States)

    ... Page Resize Text Printer Friendly Online Chat Assistive Technology Assistive technology (AT) is any service or tool that helps ... be difficult or impossible. For older adults, such technology may be a walker to improve mobility or ...

  9. Surgical Assisting

    Science.gov (United States)

    ... specific training over and above a degree in science, nursing, physician assisting, or another health profession. Prerequisites . Recommended eligibility requirements for admission into a surgical assisting program are: Bachelor of Science degree (or higher) Associate degree in an allied ...

  10. Life Management and Safety of Nuclear Facilities

    International Nuclear Information System (INIS)

    The nuclear programme in Argentina includes: nuclear power and related supplies, medical and industrial applications, waste management, research and development and human training. Nuclear facilities require life management programs that allow a safe operation. Safety is the first priority for designers and operators. This can be attained with defence in depth: regular inspections and maintenance procedures to minimize failure risks. CNEA objectives in this area are to possess the necessary capability to give safe and fast technical support. Within this scheme, one of the main activities undertaken by CNEA is to provide technological assistance to the nuclear plants and research reactors. As a consequence of an increasing concern about safety and ageing a Life Management Department for safe operation was created to take care of these subjects. The goal is to elaborate a Safety Evaluation Process for the critical components of nuclear plants and other facilities. The overall objectives of a safety process are to ensure a continuous safe, reliable and effective operation of nuclear facilities and it means the implementation of the defence in deep concept to enhance safety for the protection of the public, the workers and the environment. (author)

  11. Proton-conducting beta"-alumina via microwave-assisted synthesis and mechanism of enhanced corrosion prevention of a zinc rich coating with electronic control

    Science.gov (United States)

    Kirby, Brent William

    Proton Conducting beta-alumina via Microwave Assisted Synthesis. The microwave assisted synthesis of proton conducting Mg- and Li-stabilized NH4+/H3O+ beta-alumina from a solution based gel precursor is reported. beta-alumina is a ceramic fast ion conductor containing two-dimensional sheets of mobile cations. Na +-beta-alumina is the most stable at the sintering temperatures (1740°C) reached in a modified microwave oven, and can be ion exchanged to the K+ form and then to the NH4+/H 3O+ form. beta-phase impurity is found to be 20% for Mg-stabilized material and 30-40% for Li-stabilized material. The composition of the proton conducting form produced here is deficient in NH4 + as compared to the target composition (NH4)1.00 (H3O)0.67Mg0.67Al10.33O 17. Average grain conductivity for Li-stabilized material at 150°C is 6.6x10-3 +/- 1.6x10-3 S/cm with 0.29 +/- 0.05 eV activation energy, in agreement with single crystal studies in the literature. Grain boundary conductivity is found to be higher in the Li-stabilized material. A hydrogen bond energy hypothesis is presented to explain these differences. Li-stabilized NH4+/H3O + beta-alumina is demonstrated as a fuel cell electrolyte, producing 28 muA/cm2 of electrical current at 0.5 V. Mechanism of Enhanced Corrosion Prevention of a Zinc Rich Coating with Electronic Control. A corrosion inhibition system consisting of high weight-loading zinc rich coating applied to steel panels is examined. An electronic control unit (ECU) consisting of a battery and a large capacitor in series with the panel is shown to improve corrosion protection upon immersion in 3% NaCl solution. Weekly solution changes to avoid zinc saturation in solution system were necessary to see well differentiated results. The corrosion product, hydrozincite [Zn5(CO3) 2(OH)6] is observed to deposit within the pores of the coating and on the surface as a barrier layer. Simonkolleite [Zn5(OH) 8Cl2·H2O] is found to form in place of the original zinc particles

  12. Establishment of a rationalized safety assurance logic aiming at FBRs with enhanced social acceptance (1). Interim report of CEA/JNC collaboration NWP-5(a) from 1999 to 2001: common view and JNC's contribution

    International Nuclear Information System (INIS)

    This is an interim report describing the progress and the results of the collaborative research works between JNC and CEA on the safety logic in future fast reactors under the title of 'Establishment of a Rationalized Safety Assurance Logic Aiming at FBRs with Enhanced Social Acceptance' from 1999 to 2001. This contains JNC's contribution and common view of both partners. (1) Safety goals are proposed from JNC and CEA. Significant coherency is found such as to keep defense-in depth concept, mitigation measures against core melt are taken into account for containment design, evacuation free' concept is pursued, quantitative safety target is also considered as well as deterministic approach, and improvement of social acceptance is considered from the development stage of the fuel cycle including nuclear power plants. (2) Safety characteristics of each candidate coolant were compared and discussed. Gas-cooled fast reactor is a common interest area. Discussions are focused on: safety design requirements, safety evaluation events list, transient behavior analysis, core catcher designs, and so on. (3) JNC's results include criticality map for predicting CDA behavior and consequences, and CDA analysis results of lead-cooled and gas-cooled fast reactors with SIMMER-III. The collaboration on the action NWP-5a is recognized as being of great importance for the orientation of the innovative design studies. (author)

  13. 76 FR 60085 - National Advisory Committee on Occupational Safety and Health (NACOSH)

    Science.gov (United States)

    2011-09-28

    ... Occupational Safety and Health Administration National Advisory Committee on Occupational Safety and Health (NACOSH) AGENCY: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Request for nominations to serve on NACOSH. SUMMARY: The Assistant Secretary of Labor for Occupational Safety and......

  14. 77 FR 43616 - National Advisory Committee on Occupational Safety and Health (NACOSH)

    Science.gov (United States)

    2012-07-25

    ... Occupational Safety and Health Administration National Advisory Committee on Occupational Safety and Health (NACOSH) AGENCY: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Request for nominations to serve on NACOSH. SUMMARY: The Assistant Secretary of Labor for Occupational Safety and......

  15. 77 FR 33495 - Maritime Advisory Committee for Occupational Safety and Health (MACOSH)

    Science.gov (United States)

    2012-06-06

    ... Occupational Safety and Health Administration Maritime Advisory Committee for Occupational Safety and Health (MACOSH) AGENCY: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Notice of MACOSH..., Assistant Secretary of Labor for Occupational Safety and Health, authorized the preparation of......

  16. Auto Safety

    Science.gov (United States)

    ... 5 Things to Know About Zika & Pregnancy Auto Safety KidsHealth > For Parents > Auto Safety Print A A ... by teaching some basic rules. Importance of Child Safety Seats Using a child safety seat (car seat) ...

  17. Guidelines for the Review of Research Reactor Safety: Revised Edition. Reference Document for IAEA Integrated Safety Assessment of Research Reactors (INSARR)

    International Nuclear Information System (INIS)

    The Integrated Safety Assessment of Research Reactors (INSARR) is an IAEA safety review service available to Member States with the objective of supporting them in ensuring and enhancing the safety of their research reactors. This service consists of performing a comprehensive peer review and an assessment of the safety of the respective research reactor. The reviews are based on IAEA safety standards and on the provisions of the Code of Conduct on the Safety of Research Reactors. The INSARR can benefit both the operating organizations and the regulatory bodies of the requesting Member States, and can include new research reactors under design or operating research reactors, including those which are under a Project and Supply Agreement with the IAEA. The first IAEA safety evaluation of a research reactor operated by a Member State was completed in October 1959 and involved the Swiss 20 MW DIORIT research reactor. Since then, and in accordance with its programme on research reactor safety, the IAEA has conducted safety review missions in its Member States to enhance the safety of their research reactor facilities through the application of the Code of Conduct on the Safety of Research Reactors and the relevant IAEA safety standards. About 320 missions in 51 Member States were undertaken between 1972 and 2012. The INSARR missions and other limited scope safety review missions are conducted following the guidelines presented in this publication, which is a revision of Guidelines for the Review of Research Reactor Safety (IAEA Services Series No. 1), published in December 1997. This publication details those IAEA safety standards and guidance publications relevant to the safety of research reactors that have been revised or published since 1997. The purpose of this publication is to give guidance on the preparation, implementation, reporting and follow-up of safety review missions. It is also intended to be of assistance to operators and regulators in conducting

  18. Safety Awareness & Communications Internship

    Science.gov (United States)

    Jefferson, Zanani

    2015-01-01

    The projects that I have worked on during my internships were updating the JSC Safety & Health Action Team JSAT Employee Guidebook, conducting a JSC mishap case study, preparing for JSC Today Close Call success stories, and assisting with event planning and awareness.

  19. Ventricular assist device

    Science.gov (United States)

    VAD; RVAD; LVAD; BVAD; Right ventricular assist device; Left ventricular assist device; Biventricular assist device; Heart pump; Left ventricular assist system; LVAS; Implantable ventricular assist device

  20. On enhancement of safety culture construction and improvement of safety management%加强安全文化建设 提高安全管理水平

    Institute of Scientific and Technical Information of China (English)

    赵林

    2012-01-01

    通过分析阐明了安全文化建设对企业提高安全生产管理水平的重要性,就如何开展安全文化活动进行了探讨,并总结出安全文化建设的具体表现形式,以指导工程实践,确保生产过程中安全。%According to the analysis,the paper illustrates the importance of the safety culture construction for improving the management over the safety production in the enterprises,explores how to undertake safety cultural activities,and sums up the factual manifestation of the safety cultural construction,so as to direct the engineering practice and to ensure the safety in the production process.

  1. IAEA Response and Assistance Network. Date Effective: 1 September 2013

    International Nuclear Information System (INIS)

    accepted the new draft as resolving the critical issues that had been hindering participation. To reflect the new concept of the network, it was decided to change the name of the network to Response Assistance Network (RANET), and EPR-RANET 2006 was issued as the third edition of the assistance network publication. The 2010 edition of EPR-RANET contained minor changes in the concept of the network. The functional areas of assistance were restructured to facilitate easier registration, the name of the network was changed to Response and Assistance Network, and the responsibilities and duties of the Assistance Mission Leader were added. EPRRANET 2010 no longer had attachments, as all three of the previous RANET attachments were incorporated into the main body of the text. As was reflected in the editions of EPR-RANET up to and including the 2010 edition, RANET had primarily focused on providing assistance to manage the consequences following a nuclear or radiological incident or emergency and had not focused on the on-site assessment and management of emergencies at nuclear installations. Although assistance under the Assistance Convention was not requested and RANET was not used in response to the accident at TEPCO's Fukushima Daiichi Nuclear Power Station in March 2011, subsequent evaluation of the event identified areas where RANET could be enhanced. These were captured in the IAEA Action Plan on Nuclear Safety (GOV/2011/59-GC(55)/14), which was endorsed by the General Conference of the IAEA in September 2011. In January 2012, the IAEA Secretariat convened a consultancy meeting on the extension of RANET capabilities under the IAEA's Action Plan on Nuclear Safety. The purpose of the consultancy was to discuss the enhancement of RANET pursuant to the Action Plan, to agree on the methods to implement these enhancements, and to continue to encourage States to register their National Assistance Capabilities under RANET. The meeting concluded that ''There is a need to fully

  2. Radiation protection aspects of design for nuclear power plants. Safety guide

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the Contracting Parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  3. Radiation protection aspects in the design of nuclear power plants. Safety guide

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the Contracting Parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  4. Enhanced Sonocatalytic Degradation of Rhodamine B by Graphene-TiO2 Composites Synthesized by an Ultrasonic-Assisted Method%Enhanced Sonocatalytic Degradation of Rhodamine B by Graphene-TiO2 Composites Synthesized by an Ultrasonic-Assisted Method

    Institute of Scientific and Technical Information of China (English)

    ZHU Lei; Trisha GHOSH; Chong-Yeon PARK; MENG Ze-Da; OH Won-Chun

    2012-01-01

    A series of graphene-TiO2 composites was fabricated from graphene oxide and titanium n-butoxide (TNB) by an ultrasonic-assisted method.The structure and composition of the nanocomposites were characterized by Raman spectroscopy,BET surface area measurements,X-ray diffraction,transmission electron microscopy,and ultraviolet-visible absorption spectroscopy.The average size of the TiO2 nanoparticles on the graphene nanosheets was controlled at around 10-15 nm without using surfactant,which is attributed to the pyrolysis and condensation of dissolved TNB into TiO2 by ultrasonic irradiation.The catalytic activity of the composites under ultrasonic irradiation was determined using a rhodamine B (RhB) solution.The graphene-TiO2 composites possessed a high specific surface area,which increased the decolorization rate for RhB solution.This is because the graphene and TiO2 nanoparticles in the composites interact strongly,which enhances the photoelectric conversion of TiO2 by reducing the recombination ofphotogenerated electron-hole pairs.

  5. Generation of a safety enhanced Salmonella Gallinarum ghost using antibiotic resistance free plasmid and its potential as an effective inactivated vaccine candidate against fowl typhoid.

    Science.gov (United States)

    Jawale, Chetan V; Chaudhari, Atul A; Lee, John Hwa

    2014-02-19

    A safety enhanced Salmonella Gallinarum (SG) ghost was constructed using an antibiotic resistance gene free plasmid and evaluated its potential as fowl typhoid (FT) vaccine candidate. The antibiotic resistance free pYA3342 plasmid possesses aspartate semialdehyde dehydrogenase gene which is complimentary to the deletion of the chromosomal asd gene in the bacterial host. This plasmid was incorporated with a ghost cassette containing the bacteriophage PhiX174 lysis gene E, designated as pJHL101. The plasmid pJHL101 was transformed into a two virulence genes-deleted SG. The SG ghosts with tunnel formation and loss of cytoplasmic contents were observed by scanning electron microscopy and transmission electron microscopy. The cell viability of the culture solution was decreased to 0% at 24h after the induction of gene E expression by an increase in temperature from 37°C to 42°C. The safety and protective efficacy of the SG ghost vaccine was further examined in chickens which were divided into three groups: group A (non-immunized control), group B (orally immunized), and group C (intramuscularly immunized). The birds were immunized at 7d of age. No clinical symptoms associated with FT such as anorexia, depression and greenish diarrhea were observed in the immunized chickens. Upon challenge with a virulent SG strain at 3 week post-immunization, the chickens immunized with the SG ghost via various routes were efficiently protected, as shown by significantly lower mortality and post-mortem lesions in comparison with control group. In addition, all the immunized chickens showed significantly higher antibody responses accompanied by a potent antigen-specific lymphocyte proliferative response along with significantly increased numbers of CD4⁺ and CD8⁺ T lymphocytes. Overall, our results provide a promising approach of generating SG ghosts using the antibiotic resistance free plasmid in order to prepare a non-living bacterial vaccine candidate which could be

  6. Education and Training in Radiation, Transport and Waste Safety Newsletter, No. 3, May 2014

    International Nuclear Information System (INIS)

    Building competence through education and training in radiation protection, radioactive waste safety, and safety in transport of radioactive material is fundamental to the establishment of a comprehensive and sustainable national infrastructure for radiation safety, which in turn is essential for the beneficial uses of radiation while ensuring appropriate protection of workers, patients, the public and the environment. IAEA’s Division of Radiation, Transport and Waste Safety provides direct assistance to Member States via a range of tools and mechanisms, such as by organizing educational and training events, developing standardized syllabi with supporting material and documents, and by fostering methodologies to build sustainable competence and enhance effectiveness in the provision of training. The main objective is to support Member States in the application of the IAEA Safety Standards. Seminars and additional activities are also promoted to broaden knowledge on relevant areas for an effective application of the standards

  7. Safety Teams: An Approach to Engage Students in Laboratory Safety

    Science.gov (United States)

    Alaimo, Peter J.; Langenhan, Joseph M.; Tanner, Martha J.; Ferrenberg, Scott M.

    2010-01-01

    We developed and implemented a yearlong safety program into our organic chemistry lab courses that aims to enhance student attitudes toward safety and to ensure students learn to recognize, demonstrate, and assess safe laboratory practices. This active, collaborative program involves the use of student "safety teams" and includes hands-on safety…

  8. Schedules of Provisions of the IAEA Regulations for the Safe Transport of Radioactive Material (2005 Ed.). Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    The IAEA's Statute authorizes the Agency to establish safety standards to protect health and minimize danger to life and property - standards which the IAEA must use in its own operations, and which a State can apply by means of its regulatory provisions for nuclear and radiation safety. A comprehensive body of safety standards under regular review, together with the IAEA's assistance in their application, has become a key element in a global safety regime. In the mid-1990s, a major overhaul of the IAEA's safety standards programme was initiated, with a revised oversight committee structure and a systematic approach to updating the entire corpus of standards. The new standards that have resulted are of a high calibre and reflect best practices in Member States. With the assistance of the Commission on Safety Standards, the IAEA is working to promote the global acceptance and use of its safety standards. Safety standards are only effective, however, if they are properly applied in practice. The IAEA's safety services - which range in scope from engineering safety, operational safety, and radiation, transport and waste safety to regulatory matters and safety culture in organizations - assist Member States in applying the standards and appraise their effectiveness. These safety services enable valuable insights to be shared and I continue to urge all Member States to make use of them. Regulating nuclear and radiation safety is a national responsibility, and many Member States have decided to adopt the IAEA's safety standards for use in their national regulations. For the contracting parties to the various international safety conventions, IAEA standards provide a consistent, reliable means of ensuring the effective fulfilment of obligations under the conventions. The standards are also applied by designers, manufacturers and operators around the world to enhance nuclear and radiation safety in power generation, medicine, industry, agriculture, research and education

  9. Nuclear Safety Review 2013

    International Nuclear Information System (INIS)

    The Nuclear Safety Review 2013 focuses on the dominant nuclear safety trends, issues and challenges in 2012. The Executive Overview provides crosscutting and worldwide nuclear safety information along with a summary of the major sections covered in this report. Sections A-E of this report cover improving radiation, transport and waste safety; strengthening safety in nuclear installations; improving regulatory infrastructure and effectiveness; enhancing emergency preparedness and response (EPR); and civil liability for nuclear damage. The Appendix provides details on the activities of the Commission on Safety Standards (CSS), and activities relevant to the IAEA Safety Standards. The world nuclear community has made noteworthy progress in strengthening nuclear safety in 2012, as promoted by the IAEA Action Plan on Nuclear Safety (hereinafter referred to as ''the Action Plan''). For example, an overwhelming majority of Member States with operating nuclear power plants (NPPs) have undertaken and essentially completed comprehensive safety reassessments ('stress tests') with the aim of evaluating the design and safety aspects of plant robustness to protect against extreme events, including: defence in depth, safety margins, cliff edge effects, multiple failures, and the prolonged loss of support systems. As a result, many have introduced additional safety measures including mitigation of station blackout. Moreover, the IAEA's peer review services and safety standards have been reviewed and strengthened where needed. Capacity building programmes have been built or improved, and EPR programmes have also been reviewed and improved. Furthermore, in 2012, the IAEA continued to share lessons learned from the Fukushima Daiichi accident with the nuclear community including through three international experts' meetings (IEMs) on reactor and spent fuel safety, communication in the event of a nuclear or radiological emergency, and protection against extreme earthquakes and tsunamis

  10. Radiation safety audit

    International Nuclear Information System (INIS)

    Audit has been seen as one of the effective methods to ensure harmonization in radiation protection. A radiation safety audit is a formal safety performance examination of existing or future work activities by an independent team. Regular audit will assist the management in its mission to maintain the facilities environment that is inherently safe for its employees. The audits review the adequacy of facilities for the type of use, training, and competency of workers, supervision by authorized users, availability of survey instruments, security of radioactive materials, minimization of personnel exposure to radiation, safety equipment, and the required record keeping. All approved areas of use are included in these periodic audits. Any deficiency found in the audit shall be corrected as soon as possible after they are reported. Radiation safety audit is a proactive approach to improve radiation safety practices and identify and prevent any potential radiation accident. It is an excellent tool to identify potential problem to radiation users and to assure that safety measures to eliminate or reduce the problems are fully considered. Radiation safety audit will help to develop safety culture of the facility. It is intended to be the cornerstone of a safety program designed to aid the facility, staff and management in maintaining a safe environment in which activities are carried out. The initiative of this work is to evaluate the need of having a proper audit as one of the mechanism to manage the safety using ionizing radiation. This study is focused on the need of having a proper radiation safety audit to identify deviations and deficiencies of radiation protection programmes. It will be based on studies conducted on several institutes/radiation facilities in Malaysia in 2006. Steps will then be formulated towards strengthening radiation safety through proper audit. This will result in a better working situation and confidence in the radiation protection community

  11. Enhancing Environmental Educators' Evaluation Competencies: Insights from an Examination of the Effectiveness of the "My Environmental Education Evaluation Resource Assistant" (MEERA) Website

    Science.gov (United States)

    Zint, Michaela T.; Dowd, Patrick F.; Covitt, Beth A.

    2011-01-01

    To conduct evaluations that can benefit individual programs as well as the field as a whole, environmental educators must have the necessary evaluation competencies. This exploratory study was conducted to determine to what extent a self-directed learning resource entitled "My Environmental Education Evaluation Resource Assistant" (MEERA) can…

  12. Nuclear safety regulations

    International Nuclear Information System (INIS)

    The Nuclear Safety Regulations for Nuclear Installations and Nuclear Safety Codes for Nuclear Pressure Retaining Components were issued by the NNSA in 1995. The Atomic Act and Regulations on the Safety Regulation for Transportation of Radioactive Materials have been finished and submitted to the State Council in 1995. At the same time the NNSA organized a revised collection of regulations on nuclear safety in both Chinese and English, titled 'The Collection of Regulations on Nuclear Safety of the People's Republic of China'. To enhance the implementation of newly issued nuclear safety regulations, the NNSA conducted seven times of propagating activities in relation to the regulations for nuclear pressure retaining components and research reactors design and operating in 1995

  13. Nuclear safety

    International Nuclear Information System (INIS)

    The author proposes an overview of methods and concepts used in the nuclear industry, at the design level as well as at the exploitation level, to ensure an acceptable safety level, notably in the case of nuclear reactors. He first addresses the general objectives of nuclear safety and the notion of acceptable risk: definition and organisation of nuclear safety (relationships between safety authorities and operators), notion of acceptable risk, deterministic safety approach and main safety principles (safety functions and confinement barriers, concept of defence in depth). Then, the author addresses the safety approach at the design level: studies of operational situations, studies of internal and external aggressions, safety report, design principles for important-for-safety systems (failure criterion, redundancy, failure prevention, safety classification). The next part addresses safety during exploitation and general exploitation rules: definition of the operation domain and of its limits, periodic controls and tests, management in case of incidents, accidents or aggressions

  14. Safety evaluation of the offspring conceived by assisted reproductive technology with donor's semen%供精精液行辅助生殖技术出生子代安全性评估

    Institute of Scientific and Technical Information of China (English)

    梁明; 张斌; 孙伟; 许蓬; 张州; 杨晓玉; 曹小蓉; 胡洪亮; 李铮

    2011-01-01

    Objective: To investigate and compare the incidences of birth defects in the offspring conceived by assisted reproductive technology (ART), including artificial insemination with the donor's semen (AID), in vitro fertilization with donor's semen (IVF-D) and intracytoplasmic sperm injection with the donor's semen ( ICSI-D), and in those conceived through ART with the husband's semen, including AIH, IVF and ICSI, in order to further evaluate the safety of ART with the donor's semen.Methods: From January 2005 to October 2009, Shanghai Human Sperm Bank provided sperm copies to 11 medical institutions, which resulted in a total of 904 offspring born by ART.We followed up all these cases and investigated the status of the offspring.The control group included 4195 offspring of infertile couples from 4 Reproductive Medical Centers approved by health management administrations, which were conceived by ART in the same period.After investigating the number of offspring and cases of birth defects caused by various methods of assisted reproductive technology, we compared the incidence of birth defects resulting from the donor's semen and that from the husband's.Results: There were 7 cases of birth defects (0.77%) in the offspring bom by ART with the donor's semen, and 42 cases (1.00%) in those born by ART with the hnsband's semen, with no significant differences between the two groups (P >0.05).Conclusion: There were no significant differences in the category of birth defects between ART with the donor's semen and that with the husband's, while the incidence of birth defects resulting from ART with the donor's semen was significantly lower than that from ICSI in infertile couples.The present findings indicate a higher safety of ART with the donor's semen.%目的:本研究调查应用供精者精液实施辅助生殖技术(ART),包括供精人工授精(AID)、供精体外受精(IVF-D、ICSI-D)与应用丈夫精液经ART(AIH、IVF、ICSI)出生子代缺陷的发生率,从

  15. Robotic-assisted thermal ablation of liver tumours

    International Nuclear Information System (INIS)

    This study aimed to assess the technical success, radiation dose, safety and performance level of liver thermal ablation using a computed tomography (CT)-guided robotic positioning system. Radiofrequency and microwave ablation of liver tumours were performed on 20 patients (40 lesions) with the assistance of a CT-guided robotic positioning system. The accuracy of probe placement, number of readjustments and total radiation dose to each patient were recorded. The performance level was evaluated on a five-point scale (5-1: excellent-poor). The radiation doses were compared against 30 patients with 48 lesions (control) treated without robotic assistance. Thermal ablation was successfully completed in 20 patients with 40 lesions and confirmed on multiphasic contrast-enhanced CT. No procedure related complications were noted in this study. The average number of needle readjustment was 0.8 ± 0.8. The total CT dose (DLP) for the entire robotic assisted thermal ablation was 1382 ± 536 mGy.cm, while the CT fluoroscopic dose (DLP) per lesion was 352 ± 228 mGy.cm. There was no statistically significant (p > 0.05) dose reduction found between the robotic-assisted versus the conventional method. This study revealed that robotic-assisted planning and needle placement appears to be safe, with high accuracy and a comparable radiation dose to patients. (orig.)

  16. Robotic-assisted thermal ablation of liver tumours

    Energy Technology Data Exchange (ETDEWEB)

    Abdullah, Basri Johan Jeet; Yeong, Chai Hong [University of Malaya, Department of Biomedical Imaging and University of Malaya Research Imaging Centre, Faculty of Medicine, Kuala Lumpur (Malaysia); University of Malaya, Department of Internal Medicine, Faculty of Medicine, Kuala Lumpur (Malaysia); Goh, Khean Lee [University of Malaya, Department of Internal Medicine, Faculty of Medicine, Kuala Lumpur (Malaysia); Yoong, Boon Koon [University of Malaya, Department of Surgery, Faculty of Medicine, Kuala Lumpur (Malaysia); Ho, Gwo Fuang [University of Malaya, Department of Oncology, Faculty of Medicine, Kuala Lumpur (Malaysia); Yim, Carolyn Chue Wai [University of Malaya, Department of Anesthesia, Faculty of Medicine, Kuala Lumpur (Malaysia); Kulkarni, Anjali [Perfint Healthcare Corporation, Florence, OR (United States)

    2015-01-15

    This study aimed to assess the technical success, radiation dose, safety and performance level of liver thermal ablation using a computed tomography (CT)-guided robotic positioning system. Radiofrequency and microwave ablation of liver tumours were performed on 20 patients (40 lesions) with the assistance of a CT-guided robotic positioning system. The accuracy of probe placement, number of readjustments and total radiation dose to each patient were recorded. The performance level was evaluated on a five-point scale (5-1: excellent-poor). The radiation doses were compared against 30 patients with 48 lesions (control) treated without robotic assistance. Thermal ablation was successfully completed in 20 patients with 40 lesions and confirmed on multiphasic contrast-enhanced CT. No procedure related complications were noted in this study. The average number of needle readjustment was 0.8 ± 0.8. The total CT dose (DLP) for the entire robotic assisted thermal ablation was 1382 ± 536 mGy.cm, while the CT fluoroscopic dose (DLP) per lesion was 352 ± 228 mGy.cm. There was no statistically significant (p > 0.05) dose reduction found between the robotic-assisted versus the conventional method. This study revealed that robotic-assisted planning and needle placement appears to be safe, with high accuracy and a comparable radiation dose to patients. (orig.)

  17. OSART Guidelines. 2015 Edition. Reference Report for IAEA Operational Safety Review Teams (OSARTs)

    International Nuclear Information System (INIS)

    The IAEA works to provide a global nuclear safety and security framework for the protection of people and the environment from the effects of ionizing radiation, the minimization of the likelihood of accidents that could endanger life and property, and effective mitigation of the effects of any such events, should they occur. The strategic approach to achieving such a framework involves continual improvement in four areas: national and international safety infrastructures; the establishment and global acceptance of IAEA safety standards; an integrated approach to the provision for the application of the safety standards; and a global network of knowledge and experience. The IAEA Operational Safety Review Team (OSART) programme provides advice and assistance to Member States to enhance the safety of nuclear power plants during commissioning and operation. The OSART programme, initiated in 1982, is available to all Member States with nuclear power plants under commissioning or in operation. Conservative design, careful manufacture and sound construction are all prerequisites for the safe operation of nuclear power plants. However, the safety of the plant also depends ultimately on: sound management, policies, procedures, processes and practices; the capability and reliability of commissioning and operating personnel; comprehensive instructions; sound accident management and emergency preparedness; and adequate resources. Finally, a positive attitude and conscientiousness on the part of all staff in discharging their responsibilities is important to safety. The OSART programme is based on the safety standards applicable to nuclear power plants. IAEA safety standards reflect the consensus of Member States on nuclear safety matters. The reports of the International Nuclear Safety Group identify important current nuclear safety issues and also serve as references during an OSART review. The publication OSART Guidelines provides overall guidance on the conduct of OSART

  18. Efficacy and safety of endoscopic papillary balloon dilation for the removal of bile duct stones: Data from a “real-life” multicenter study on Dilation-Assisted Stone Extraction

    Science.gov (United States)

    Di Mitri, Roberto; Mocciaro, Filippo; Pallio, Socrate; Pecoraro, Giulia Maria; Tortora, Andrea; Zulli, Claudio; Attardo, Simona; Maurano, Attilio

    2016-01-01

    AIM To report data on Dilation-Assisted Stone Extraction (DASE) use in clinical practice and its efficacy and safety trough three Italian referral centers for biliopancreatic diseases treatment. METHODS From January 2011 to December 2015 we collected data on 120 patients treated with DASE. Technical success was obtained when the endoscopist was able to place the balloon trough the papilla inflating the balloon until the final diameter for an adequate time (at least 30 s). Clinical success was obtained after complete stone removal (no remaining stones were visible at the cholangiogram). RESULTS Forty-nine male (40.8%) and 71 female (59%) were enrolled. The mean age was 67.8 years ± 15.7. The mean common bile duct (CBD) dilation was 19.2 mm ± 3.9 and the mean size of stones 15.8 ± 2.9. DASE was applied as first approach in 38% (62% after initial failure of stones extraction). Technical and clinical success was of 91% and 87% respectively. In those in which DASE failed alternative treatment were adopted. After DASE 18% of patients experienced a complication (bleeding 9%, pancreatitis 8%, perforation 0.8%). At univariable analysis, elective endoscopic retrograde cholangiopancreatography (P = 0.031), DASE as first approach (P = 0.032), and cannulation of major papilla followed by guidewire insertion (P = 0.004) were related to low risk of complications. Pre-cut was related to an increased risk of complications (P = 0.01). CONCLUSION DASE allowed a higher first-session success rate and can be consider a valid alternative to endoscopic sphincterotomy not only for bigger CBD stones. PMID:27803771

  19. Safety culture

    Energy Technology Data Exchange (ETDEWEB)

    Keen, L.J. [Canadian Nuclear Safety Commission, Ottawa, Ontario (Canada)

    2003-07-01

    Safety culture has become a topic of increasing interest for industry and regulators as issues are raised on safety problems around the world. The keys to safety culture are organizational effectiveness, effective communications, organizational learning, and a culture that encourages the identification and resolution of safety issues. The necessity of a strong safety culture places an onus on all of us to continually question whether the safety measures already in place are sufficient, and are being applied. (author)

  20. Weatherization and Intergovernmental Program - Weatherization Assistance Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-06-01

    The U.S. Department of Energy’s (DOE) Weatherization Assistance Program reduces energy costs for low-income households by increasing the energy efficiency of their homes, while ensuring their health and safety.

  1. Management of safety culture

    International Nuclear Information System (INIS)

    The strengthening of safety culture in an organization has become an increasingly important issue for nuclear industry. A high level of safety performance is essential for business success in intensely competitive global environment. This presentation offers a discussion of some principles and activities used in enhancing safety performance and appropriate safety behaviour at the Krsko NPP. Over the years a number of events have occurred in nuclear industry that have involved problems in human performance. A review of these and other significant events has identified recurring weaknesses in plant safety culture and policy. Focusing attention on the strengthening of relevant processes can help plants avoid similar undesirable events. The policy of the Krsko NPP is that all employees concerned shall constantly be alert to opportunities to reduce risks to the lowest practicable level and to achieve excellence in plant safety. The most important objective is to protect individuals, society and the environment by establishing and maintaining an effective defense against radiological hazard in the nuclear power plant. It is achieved through the use of reliable structures, components, systems, and procedures, as well as plant personnel committed to a strong safety culture. The elements of safety culture include both organizational and individual aspects. Elements commonly included at the organizational level are senior management commitment to safety, organizational effectiveness, effective communication, organizational learning, and a culture that encourages identification and resolution of safety issues. Elements identified at the individual level include personal accountability, a questioning attitude, communication, procedural adherence, etc.(author)

  2. CANDU energy for steam assisted gravity drainage

    International Nuclear Information System (INIS)

    Traditional open-pit mining has been used by industry for many years to remove oil sands from shallow deposits. To increase production capacity, the industry is looking for new technology to exploit bitumen from deep deposits. Among them, SAGD (Steam-Assisted Gravity Drainage) appears to be the most promising approach. It uses steam to remove bitumen from underground reservoirs. Recently, the SAGD recovery process has been put into commercial operation by major oil companies.Atomic Energy Canada Limited has assessed the use of the ACR-1000 as a source of heat and electricity for oil sand extraction and processing. The ACR-1000 design is an evolutionary development of the familiar CANDU technology, adding innovations to enhance economics, operations, and safety margins. The net electrical output from a standard ACR-1000 will be close to 1100 MWe, depending on local cooling water temperature

  3. Speech and language therapy students’ experience of peer assisted learning:Undergraduates investigate PAL as a means of enhancing academic and professional development

    OpenAIRE

    Guyon, Anne; Butterfint, Zoe; Lacy, Andrea; Sanosi, Aisha; Sheridan, Katie; Unwin, Jessica

    2015-01-01

    The implementation of Peer Assisted Learning (PAL) on healthcare courses in Higher Education Institutions has been explored in a number of studies. This paper presents research into the experience of PAL on a BSc Speech & Language Therapy (SLT) programme. The research was conducted by final year undergraduate SLT students to form the basis for their final dissertations. The focus for their research was on the effects of PAL on academic and professional development for both mentees and mentors...

  4. Ionic liquid assisted chemical strategy to TiO2 hollow nanocube assemblies with surface-fluorination and nitridation and high energy crystal facet exposure for enhanced photocatalysis.

    Science.gov (United States)

    Yu, Shengli; Liu, Baocang; Wang, Qin; Gao, Yuxi; Shi, Ying; Feng, Xue; An, Xiaoting; Liu, Lixia; Zhang, Jun

    2014-07-01

    Realization of anionic nonmetal doping and high energy crystal facet exposure in TiO2 photocatalysts has been proven to be an effective approach for significantly improving their photocatalytic performance. A facile strategy of ionic liquid assisted etching chemistry by simply hydrothermally etching hollow TiO2 spheres composed of TiO2 nanoparticles with an ionic liquid of 1-butyl-3-methylimidazolium tetrafluoroborate without any other additives is developed to create highly active anatase TiO2 nanocubes and TiO2 nanocube assemblies. With this one-pot ionic liquid assisted etching process, the surface-fluorination and nitridation and high energy {001} crystal facets exposure can be readily realized simultaneously. Compared with the benchmark materials of P25 and TiO2 nanostructures with other hierarchical architectures of hollow spheres, flaky spheres, and spindles synthesized by hydrothermally etching hollow TiO2 spheres with nonionic liquid of NH4F, the TiO2 nanocubes and TiO2 nanocube assemblies used as efficient photocatalysts show super high photocatalytic activity for degradation of methylene blue, methyl orange, and rhodamine B, due to their surface-fluorination and nitridation and high energy crystal facet exposure. The ionic liquid assisted etching chemistry is facile and robust and may be a general strategy for synthesizing other metal oxides with high energy crystal facets and surface doping for improving photocatalytic activity. PMID:24881462

  5. Nuclear safety review 1990

    International Nuclear Information System (INIS)

    The Nuclear Safety Review summarizes international developments in nuclear safety and radiation protection that are of importance in keeping nuclear power production and the uses of radiation among the safest of industrial activities. Major political changes in Europe have led to requests from eastern European countries for assistance in reassessing the safety of their nuclear power plants in operation and under construction. For its part in providing such assistance, the IAEA has expanded and extended the various advisory services in nuclear safety and radiation protection that it makes available to its Member States. The accident at the Chernobyl nuclear power plant in 1986 continues to be a primary influence on developments in nuclear safety and radiation protection. Work has been initiated to set up an international research centre in the Chernobyl area for studies relating to the consequences of accidents at nuclear establishments. In the interim, at the request of the USSR, the IAEA has commenced a limited reassessment of the radiological consequences of the Chernobyl accident for the public health and the environment in areas of the three Soviet republics most affected. Four other international organizations are participating in the study. Refs, figs and tabs

  6. Dukovany nuclear power plant safety

    International Nuclear Information System (INIS)

    Presentation covers recommended safety issues for the Dukovany NPP which have been solved with satisfactory conclusions. Safety issues concerned include: radiation safety; nuclear safety; security; emergency preparedness; health protection at work; fire protection; environmental protection; chemical safety; technical safety. Quality assurance programs at all stages on NPP life time is described. Report includes description of NPP staff training provision, training simulator, emergency operating procedures, emergency preparedness, Year 2000 problem, inspections and life time management. Description of Dukovany Plant Safety Analysis Projects including integrity of the equipment, modernisation, equipment innovation and safety upgrading program show that this approach corresponds to the actual practice applied in EU countries, and fulfilment of current IAEA requirements for safety enhancement of the WWER 440/213 units in the course of MORAWA Equipment Upgrading program

  7. Delivering safety

    International Nuclear Information System (INIS)

    In the United Kingdom there have been significant recent changes to the management of civil nuclear liabilities. With the formation in April 2005 of the Nuclear Decommissioning Authority (NDA), ownership of the civil nuclear licensed sites in the UK, including the Magnox Reactor Stations, passed to this new organisation. The NDAs mission is to seek acceleration of the nuclear clean up programme and deliver increased value for money and, consequently, are driving their contractors to seek more innovative ways of performing work. British Nuclear Group manages the UK Magnox stations under contract to the NDA. This paper summarises the approach being taken within its Reactor Sites business to work with suppliers to enhance working arrangements at sites, improve the delivery of decommissioning programmes and deliver improvements in safety and environmental performance. The UK Magnox stations are 1. generation gas-graphite reactors, constructed in the 1950's and 1960's. Two stations are currently still operating, three are shut-down undergoing defueling and the other five are being decommissioned. Despite the distractions of industry restructuring, an uncompromising policy of demanding improved performance in conjunction with improved safety and environmental standards has been adopted. Over the past 5 years, this policy has resulted in step-changes in performance at Reactor Sites, with increased electrical output and accelerated defueling and decommissioning. The improvements in performance have been mirrored by improvements in safety (DACR of 0 at 5 sites); environmental standards (reductions in energy and water consumption, increased waste recycling) and the overall health of the workforce (20% reduction in sickness absence). These achievements have, in turn, been recognised by external bodies, resulting in several awards, including: the world's first ISRS and IERS level 10 awards (Sizewell, 2006), the NUMEX plant maintenance award (Bradwell, 2006), numerous Ro

  8. Synthesis and evaluation of sodium deoxycholate sulfate as a lipid drug carrier to enhance the solubility, stability and safety of an amphotericin B inhalation formulation.

    Science.gov (United States)

    Gangadhar, Katkam N; Adhikari, Kajiram; Srichana, Teerapol

    2014-08-25

    Amphotericin B (AmB) is still used as the gold standard for therapy against invasive fungal diseases. However, the use of AmB through oral administration is restricted due to its low solubility and stability in aqueous solution, which is the cause for its poor bioavailability and highly varying absorption. Therefore, an attempt has been made to enhance the solubility and stability of AmB to evaluate its bioactivity and safety for use as an inhaler by using a new excipient sodium deoxycholate sulfate (SDS) with aim of using it as a drug carrier for AmB. Therefore, SDS was formulated together with AmB as a dry powder by lyophilization. The dry powder was reconstituted in distilled water and evaluated its physicochemical properties such as zeta potential, particle size and pH to compare its solubility and stability of the formulations with a SDC-AmB (i.e., known as Fungizone(®)). In vitro toxicity studies were carried out with red blood cells (RBC) and respiratory cell lines. Bioactivity was determined by a micro-dilution method against Candidaalbicans and Cryptococcusneoformans. We found that SDS-AmB had a zeta potential (-45.53 mV), which was higher than of Fungizone(®); and produced a stable particle size in solution (73.8 nm). The particle size distributions of both formulations were expressed as their mass median aerodynamic diameters (MMAD; 1.70 and 1.74 μm), their fine particle fractions (FPF; 70 and 80%) and geometric standard deviations (GSD; 2.3 and 2.0), respectively. These values indicated that the sizes were appropriate for use in an inhaler. Pure AmB was found to hemolyse RBC and was very toxic to alveolar macrophage cells, as their viability rapidly declined from 93 to 56% when the AmB concentration increased from 1 to 8 μg/mL. The SDS-AmB formulation had a significantly reduced toxicity compared to AmB. The results clearly indicated that the SDS-lipid based nanoparticles had the potential to be used as an alternative option to Fungizone(®) for an

  9. Assisted Ventilation.

    Science.gov (United States)

    Dries, David J

    2016-01-01

    Controlled Mechanical Ventilation may be essential in the setting of severe respiratory failure but consequences to the patient including increased use of sedation and neuromuscular blockade may contribute to delirium, atelectasis, and diaphragm dysfunction. Assisted ventilation allows spontaneous breathing activity to restore physiological displacement of the diaphragm and recruit better perfused lung regions. Pressure Support Ventilation is the most frequently used mode of assisted mechanical ventilation. However, this mode continues to provide a monotonous pattern of support for respiration which is normally a dynamic process. Noisy Pressure Support Ventilation where tidal volume is varied randomly by the ventilator may improve ventilation and perfusion matching but the degree of support is still determined by the ventilator. Two more recent modes of ventilation, Proportional Assist Ventilation and Neurally Adjusted Ventilatory Assist (NAVA), allow patient determination of the pattern and depth of ventilation. Proposed advantages of Proportional Assist Ventilation and NAVA include decrease in patient ventilator asynchrony and improved adaptation of ventilator support to changing patient demand. Work of breathing can be normalized with these modes as well. To date, however, a clear pattern of clinical benefit has not been demonstrated. Existing challenges for both of the newer assist modes include monitoring patients with dynamic hyperinflation (auto-positive end expiratory pressure), obstructive lung disease, and air leaks in the ventilator system. NAVA is dependent on consistent transduction of diaphragm activity by an electrode system placed in the esophagus. Longevity of effective support with this technique is unclear. PMID:25501776

  10. Public safety around dams

    Energy Technology Data Exchange (ETDEWEB)

    Pastinak, O. [Ontario Ministry of Natural Resources, Toronto, ON (Canada)

    2009-07-01

    Ontario's current dam safety program is administered under guidelines and there is no regulation in place. It is a reactive program that is administered by area supervisors and regional engineers with support from policy, legal and enforcement branches. Currently, there are no regulatory requirements for inspections, dam classifications, public safety measures, emergency preparedness plans, operations and maintenance, or dam registration. This presentation proposed improvements to Ontario's current dam safety program and highlighted the imperatives for public safety around dams. The presentation also discussed the proposed elements of enhanced public safety requirements. The proposed measures would involve moving from a reactive, guidelines-based program to a regulated program under the Lakes and Rivers Improvement Act. The presentation discussed why public safety around dams should be regulated and provided an overview of dam related fatalities in Ontario. A public safety framework and public safety assessment report were also discussed. Registration of incidents and public safety measures were addressed. figs.

  11. Enhanced adsorption of chromium onto activated carbon by microwave-assisted H(3)PO(4) mixed with Fe/Al/Mn activation.

    Science.gov (United States)

    Sun, Yuanyuan; Yue, Qinyan; Mao, Yanpeng; Gao, Baoyu; Gao, Yuan; Huang, Lihui

    2014-01-30

    FeCl3, AlCl3 and MnCl2 were used as the assisted activation agent in activated carbon preparation by H3PO4 activation using microwave heating method. The physico-chemical properties of activated carbons were investigated by scanning electron microscope (SEM), N2 adsorption/desorption, Boehm's titration, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS). To investigate the adsorption performances of chromium onto these newly developed activated carbons, a batch of experiments were performed under different adsorption conditions: solution pH, initial Cr(VI) ion concentration, contact time and co-existing ions. The results suggested that carbon with MnCl2 as assisted activation agent displayed the highest BET surface area (1332m(2)/g) and the highest pore volume (1.060cm(3)/g). FeCl3, AlCl3 and MnCl2 had successfully improved Cr(VI) adsorption and activated carbon with FeCl3 as assisted activation agent exhibited the best uptake capacity. To study the transformation of Cr(VI) in adsorption process, total chromium in the aqueous solution was also recorded. The ratio of the amount of Cr(VI) to Cr(III) on each adsorbent was explained by XPS analysis results. Both the co-existing salts (Na2SO4 and NaNO3) demonstrated promoted effects on Cr(VI) removal by four carbons. The pseudo-second-order model and Freundlich equation displayed a good correlation with adsorption data.

  12. Nuclear safety in perspective

    DEFF Research Database (Denmark)

    Andersson, K.; Sjöberg, B.M.D.; Lauridsen, Kurt;

    2003-01-01

    The aim of the NKS/SOS-1 project has been to enhance common understanding about requirements for nuclear safety by finding improved means of communicat-ing on the subject in society. The project, which has been built around a number of seminars, wassupported by limited research in three sub......-projects: Risk assessment Safety analysis Strategies for safety management The report describes an industry in change due to societal factors. The concepts of risk and safety, safety management and systems forregulatory oversight are de-scribed in the nuclear area and also, to widen the perspective, for other...... industrial areas. Transparency and public participation are described as key elements in good risk communication, and case studies are given.Environmental Impact Assessment and Strategic Environmental Assessment are described as important overall proces-ses within which risk communication can take place...

  13. Robotic assisted andrological surgery

    Institute of Scientific and Technical Information of China (English)

    Sijo J Parekattil; Ahmet Gudeloglu

    2013-01-01

    The introduction of the operative microscope for andrological surgery in the 1970s provided enhanced magnification and accuracy,unparalleled to any previous visual loop or magnification techniques.This technology revolutionized techniques for microsurgery in andrology.Today,we may be on the verge of a second such revolution by the incorporation of robotic assisted platforms for microsurgery in andrology.Robotic assisted microsurgery is being utilized to a greater degree in andrology and a number of other microsurgical fields,such as ophthalmology,hand surgery,plastics and reconstructive surgery.The potential advantages of robotic assisted platforms include elimination of tremor,improved stability,surgeon ergonomics,scalability of motion,multi-input visual interphases with up to three simultaneous visual views,enhanced magnification,and the ability to manipulate three surgical instruments and cameras simultaneously.This review paper begins with the historical development of robotic microsurgery.It then provides an in-depth presentation of the technique and outcomes of common robotic microsurgical andrological procedures,such as vasectomy reversal,subinguinal varicocelectomy,targeted spermatic cord denervation (for chronic orchialgia) and robotic assisted microsurgical testicular sperm extraction (microTESE).

  14. Groundwater well services site safety and health plan

    International Nuclear Information System (INIS)

    This Site Specific Health and Safety Plan covers well servicing in support of the Environmental Restoration Contractor Groundwater Project. Well servicing is an important part of environmental restoration activities supporting several pump and treat facilities and assisting in evaluation and servicing of various groundwater wells throughout the Hanford Site. Remediation of contaminated groundwater is a major part of the ERC project. Well services tasks help enhance groundwater extraction/injection as well as maintain groundwater wells for sampling and other hydrologic testing and information gathering

  15. Effective learning techniques for military applications using the Personalized Assistant that Learns (PAL) enhanced Web-Based Temporal Analysis System (WebTAS)

    Science.gov (United States)

    LaMonica, Peter; Dziegiel, Roger; Liuzzi, Raymond; Hepler, James

    2009-05-01

    The Personalized Assistant that Learns (PAL) Program is a Defense Advanced Research Projects Agency (DARPA) research effort that is advancing technologies in the area of cognitive learning by developing cognitive assistants to support military users, such as commanders and decision makers. The Air Force Research Laboratory's (AFRL) Information Directorate leveraged several core PAL components and applied them to the Web-Based Temporal Analysis System (WebTAS) so that users of this system can have automated features, such as task learning, intelligent clustering, and entity extraction. WebTAS is a modular software toolset that supports fusion of large amounts of disparate data sets, visualization, project organization and management, pattern analysis and activity prediction, and includes various presentation aids. WebTAS is predominantly used by analysts within the intelligence community and with the addition of these automated features, many transition opportunities exist for this integrated technology. Further, AFRL completed an extensive test and evaluation of this integrated software to determine its effectiveness for military applications in terms of timeliness and situation awareness, and these findings and conclusions, as well as future work, will be presented in this report.

  16. IAEA Safety Standards on Management Systems and Safety Culture

    Directory of Open Access Journals (Sweden)

    K.D. Persson

    2007-01-01

    Full Text Available The IAEA has developed a new set of Safety Standards for applying an integrated Management System for facilities and activities. The objective of the new Safety Standards is to define requirements and provide guidance for establishing, implementing, assessing and continually improving a Management System that integrates safety, health, environmental, security, quality and economic related elements to ensure that safety is properly taken into account in all the activities of an organization. With an integrated approach to management systems it is also necessary to include the aspect of culture, where the organizational culture and safety culture is seen as crucial elements of the successful implementation of this management system and the attainment of all the goals and particularly the safety goals of the organization. The IAEA has developed a set of services aimed at assisting it’s Member States in establishing, implementing, assessing and continually improving an integrated management system.

  17. IAEA Safety Standards on Management Systems and Safety Culture

    International Nuclear Information System (INIS)

    The IAEA has developed a new set of Safety Standard for applying an integrated Management System for facilities and activities. The objective of the new Safety Standards is to define requirements and provide guidance for establishing, implementing, assessing and continually improving a Management System that integrates safety, health, environmental, security, quality and economic related elements to ensure that safety is properly taken into account in all the activities of an organization. With an integrated approach to management system it is also necessary to include the aspect of culture, where the organizational culture and safety culture is seen as crucial elements of the successful implementation of this management system and the attainment of all the goals and particularly the safety goals of the organization. The IAEA has developed a set of service aimed at assisting it's Member States in establishing. Implementing, assessing and continually improving an integrated management system. (author)

  18. Periodic Safety Review of Nuclear Power Plants: Experience of Member States

    International Nuclear Information System (INIS)

    Routine reviews of nuclear power plant operation (including modifications to hardware and procedures, operating experience, plant management and personnel competence) and special reviews following major events of safety significance are the primary means of safety verification. In addition, many Member States of the IAEA have initiated systematic safety reassessments, termed periodic safety reviews, of nuclear power plants, to assess the cumulative effects of plant ageing and plant modifications, operating experience, technical developments and siting aspects. The reviews include an assessment of plant design and operation against current safety standards and practices, and they have the objective of ensuring a high level of safety throughout the plant's operating lifetime. They are complementary to the routine and special safety reviews and do not replace them. Periodic safety reviews of nuclear power plants are considered an effective way to obtain an overall view of actual plant safety, and to determine reasonable and practical modifications that should be made in order to maintain a high level of safety. They can be used as a means of identifying time limiting features of the plant in order to determine nuclear power plant operation beyond the designed lifetime. The periodic safety review process can be used to support the decision making process for long term operation or licence renewal. Since 1994, the use of periodic safety reviews by Member States has substantially broadened and confirmed its benefits. Periodic safety review results have, for example, been used by some Member States to help provide a basis for continued operation beyond the current licence term, to communicate more effectively with stakeholders regarding nuclear power plant safety, and to help identify changes to plant operation that enhance safety. This IAEA-TECDOC is intended to assist Member States in the implementation of a periodic safety review. This publication complements the

  19. Enhancement of reliability of PLT-safety devices by utilization of process control components; Steigerung der Verfuegbarkeit von PLT-Schutzeinrichtungen durch Mitbenutzung von Komponenten des Prozessleitsystems

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, T.; Litz, L. [Technische Univ. Kaiserslautern (Germany); Schroers, B. [Material-Science AG, Leverkusen (Germany)

    2008-01-15

    According to the standard IEC 61511 each safety-related loop is assigned to one of the four Safety Integrity Levels (SILs). For every safety-related loop a SIL-specific Probability of Failure on Demand (PFD) must be proven. Usually, the PFD calculation is performed based upon the failure rates of each loop component aided by commercial software tools. However, this bottom-up approach suffers from many uncertainties. Especially, a lack of reliable failure rate data causes many problems. Reference data collected in different environments are available to solve this situation. However, this pragmatism leads to a PFD bandwidth, not to a single PFD value as desired. In order to make a decision for a numerical value appropriate for the chemical and pharmaceutical process industry a data ascertainment has been initiated by the European NAMUR. Its results display large deficiencies for the bottom-up approach. The error sources leading to this situation are located and analyzed. (GL)

  20. Quantum sized Ag nanocluster assisted fluorescence enhancement in Tm{sup 3+}-Yb{sup 3+} doped optical fiber beyond plasmonics

    Energy Technology Data Exchange (ETDEWEB)

    Chattopadhyay, Rik; Haldar, Arindam; Paul, Mukul C.; Das, Shyamal; Bhadra, Shyamal K., E-mail: skbhadra@cgcri.res.in [Fiber Optics and Photonics Division, CSIR-Central Glass and Ceramic Research Institute, 196, Raja S. C. Mullick Road, Kolkata 700032 (India)

    2015-12-07

    We report a process for enhancing fluorescence emission from conventional rare earth ions in optical fiber by metal nanocluster (MNC) in nonresonant indirect pumping. The process is completely different from formal metal enhanced fluorescence phenomenon as the MNCs are too small in size to support localized surface plasmon and the excitation wavelength is far from plasmon resonance frequency. We used an established theory of two coupled oscillators to explain the simultaneous enhancement of Ytterbium (Yb{sup 3+}) and Thulium (Tm{sup 3+}) emission by silver (Ag) NCs under nonresonant pumping in optical fiber. The fiber is pumped with a 980 nm fiber pigtailed laser diode with input power of 20–100 mW to excite the Yb{sup 3+}. Four times enhancement of Yb{sup 3+} emission of 900–1100 nm and Tm{sup 3+} upconversion emission around 474 nm, 650 nm, and 790 nm is observed in the fiber with Ag NCs.