WorldWideScience

Sample records for assessment topics thermal

  1. Thermal Water of Utah Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Goode, Harry D.

    1978-11-01

    Western and central Utah has 16 areas whose wells or springs yield hot water (35 C or higher), warm water (20-34.5 C), and slightly warm water (15.5-19.5 C). These areas and the highest recorded water temperature for each are: Lower Bear River Area, 105 C; Bonneville Salt Flats, 88 C; Cove Fort-Sulphurdale, 77 C; Curlew Valley, 43 C; East Shore Area, 60 C; Escalante Desert, 149 C; Escalante Valley (Roosevelt, 269 C, and Thermo, 85C); Fish Springs, 60.5 C; Grouse Creek Valley, 42 C; Heber Valley (Midway, 45 C); Jordan Valley, 58.5 C; Pavant Valley-Black Rock Desert, 67 C; Sevier Desert ( Abraham-Crater Hot Springs, 82 C); Sevier Valley (Monroe-Red Hill, 76.5 C, and Joseph Hot Spring, 64 C); Utah Valley, 46 C; and Central Virgin River Basin, 42 C. The only hot water in eastern Utah comes from the oil wells of the Ashley Valley Oil Field, which in 1977 yielded 4400 acre-feet of water at 43 C to 55 C. Many other areas yield warm water (20 to 34.5 C) and slightly warm water (15.5 to 19.5 C). With the possible exception of the Roosevelt KGRA, Crater Hot Springs in the Sevier Desert, Escalante Desert, Pavant-Black Rock, Cove Fort-Sulphurdale, and Coyote Spring in Curlew Valley, which may derive their heat from buried igneous bodies, the heat that warms the thermal water is derived from the geothermal gradient. Meteoric water circulates through fractures or permeable rocks deep within the earth, where it is warmed; it then rises by convection or artesian pressure and issues at the surface as springs or is tapped by wells. Most thermal springs thus rise along faults, but some thermal water is trapped in confined aquifers so that it spreads laterally as it mixes with and warms cooler near-surface water. This spreading of thermal waters is evident in Cache Valley, in Jordan Valley, and in southern Utah Valley; likely the spreading occurs in many other artesian basins where it has not yet been recognized. In the East Shore Area thermal water trapped in confined aquifers warms

  2. Risk assessment of topically applied products

    DEFF Research Database (Denmark)

    Søborg, Tue; Basse, Line Hollesen; Halling-Sørensen, Bent

    2007-01-01

    The human risk of harmful substances in semisolid topical dosage forms applied topically to normal skin and broken skin, respectively, was assessed. Bisphenol A diglycidyl ether (BADGE) and three derivatives of BADGE previously quantified in aqueous cream and the UV filters 3-BC and 4-MBC were used...... as model compounds. Tolerable daily intake (TDI) values have been established for BADGE and derivatives. Endocrine disruption was chosen as endpoint for 3-BC and 4-MBC. Skin permeation of the model compounds was investigated in vitro using pig skin membranes. Tape stripping was applied to simulate broken...... parameters for estimating the risk. The immediate human risk of BADGE and derivatives in topical dosage forms was found to be low. However, local treatment of broken skin may lead to higher exposure of BADGE and derivatives compared to application to normal skin. 3-BC permeated skin at higher flux than 4-MBC...

  3. Solar thermal energy as a topic in secondary mathematics classrooms

    Energy Technology Data Exchange (ETDEWEB)

    Brinkmann, A.; Brinkmann, K. [EnviPro Environmental Process Engineering Prof. Dr. Klaus Brinkmann, Iserlohn (Germany)

    2004-07-01

    One of the most effective methods to achieve a sustainable change of our momentary existing power supply system to a system mainly based on renewable energy conversion is the education of our children. For this purpose the compulsory school subject mathematics appears to be suitable. In order to promote renewable energy issues in mathematics classrooms, the authors have developed a special didactical concept to open this field for students, as well as for their teachers. The aim of this paper is to present firstly an overview of our concept and secondly examples of problems to the special topic of solar thermal energy, developed on the basis of our concept. (orig.)

  4. Assessing adherence factors in patients under topical treatment: development of the Topical Therapy Adherence Questionnaire (TTAQ).

    Science.gov (United States)

    Zschocke, Ina; Mrowietz, Ulrich; Lotzin, Annett; Karakasili, Eleni; Reich, Kristian

    2014-04-01

    Medication adherence rates strongly depend on favorable disease outcomes. It is known that medication adherence rates are lower for topical treatment than for systemic treatment. However, to date no validated instrument for the assessment of adherence factors in topical treatment is available. The aim of this study was to develop a new questionnaire to assess adherence risk factors in topical treatment. The development of the Topical Therapy Adherence Questionnaire (TTAQ) and Patient Preference Questionnaire (PPQ) was based on a systematic literature review, and qualitative patient focus interviews and expert focus groups' input. The psychometric properties and comprehensibility of the TTAQ and PPQ were assessed in a feasibility study with 59 psoriasis patients. Our first preliminary results indicate that the TTAQ and PPQ are psychometrically sound and reliable measures for the assessment of factors influencing topical treatment adherence. The questionnaires are currently being further developed and various parameters (e.g., time point of assessment) are currently being tested in an exploratory pilot study with ca. 2,000 psoriasis patients receiving topical treatment in a European clinical trial. The use of the final versions of TTAQ and PPQ in clinical practice may facilitate the early identification of specific non-adherence factors in patients under topical treatment, which could enable designing and applying adherence-enhancing interventions according to the patient's individual needs.

  5. Proceedings of the Twenty-First Water Reactor Safety Information Meeting: Volume 1, Plenary session; Advanced reactor research; advanced control system technology; advanced instrumentation and control hardware; human factors research; probabilistic risk assessment topics; thermal hydraulics; thermal hydraulic research for advanced passive LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Monteleone, S. [Brookhaven National Lab., Upton, NY (United States)] [comp.

    1994-04-01

    This three-volume report contains 90 papers out of the 102 that were presented at the Twenty-First Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, during the week of October 25--27, 1993. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Germany, Japan, Russia, Switzerland, Taiwan, and United Kingdom. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. Individual papers have been cataloged separately. This document, Volume 1 covers the following topics: Advanced Reactor Research; Advanced Instrumentation and Control Hardware; Advanced Control System Technology; Human Factors Research; Probabilistic Risk Assessment Topics; Thermal Hydraulics; and Thermal Hydraulic Research for Advanced Passive Light Water Reactors.

  6. Topical ketorolac has no antinociceptive or anti-inflammatory effect in thermal injury

    DEFF Research Database (Denmark)

    Møiniche, S; Pedersen, J L; Kehlet, H

    1994-01-01

    detection thresholds (MPDT) and the intensity of burn-induced erythema (erythema index, EI) were assessed in the area of the thermal injury, and areas of hyperalgesia to pin prick were determined outside the injury before and 3, 6 and 24 h after the burn injury. Burn injury led to a decrease in HPDT, HPT......This study investigated the antinociceptive and anti-inflammatory effect of a topical non-steroidal anti-inflammatory drug in human thermal injury. Twelve healthy unmedicated volunteers had identical burn injuries produced on the medial side of both calves with a 49 degrees C 15 x 25 mm thermode...... and MPDT, an increase in EI and development of mechanical hyperalgesia (P 0.2)....

  7. Industrial thermal insulation: an assessment

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, R.G.; Tennery, V.J.; McElroy, D.L.; Godfrey, T.G.; Kolb, J.O.

    1976-03-01

    A large variety of thermal insulation materials is manufactured for application in various temperature ranges and environments. Additional and improved thermal insulation for steam systems is a key area with immediate energy conservation potential in several of the larger energy-consuming industries. Industrial thermal insulation technology was assessed by obtaining input from a variety of sources including insulation manufacturers, system designers, installers, users, consultants, measurement laboratories, open literature, and in-house knowledge. The assessment identified a number of factors relevant to insulation materials and usage that could contribute significantly to improved energy conservation.

  8. Thermal depolymerization of plastics - PDU testing. Task 15. Topical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    The process development unit (PDU) test program is part of an ongoing effort at the Energy & Environmental Research Center (EERC) to expand the base of knowledge for the thermal depolymerization of plastics process. This phase of the development effort, initiated after successful completion of a bench-scale program, has concentrated on maximizing liquid yield. The purposes of the PDU program were (1) to demonstrate the process on a commercially scalable unit, (2) to produce quantities of product that could be used to initiate discussions with potential end users, and (3) to gather engineering and yield data. Experimentation consisted of eleven test points on the PDU and seven on the continuous fluid-bed reactor (CFBR) bench-scale unit. Initial PDU tests (PO35-PO39) were carried out using a base blend, which consists of 60% high-density polyethylene (HDPE), 20% polypropylene (PP), and 20% polystyrene (PS) virgin resin pellets. Test PO39 used base blend with 5% polyvinyl chloride (PVC). The base blend decomposed to produce a flowable liquid, with liquid yields ranging from 33% to 45%. The next series of tests, PO40-PO44, used a postconsumer plastics feed. This material did not decompose as readily as the base blend and formed a very waxy, heavy liquid, with {open_quotes}liquid{close_quotes} yields ranging from 18% to 63% (low liquid yields are the result of using excess air in the natural gas burner in some tests in an attempt to increase gas residence time).

  9. The Effect of Topical Local Anesthetics on Thermal Pain Sensitivity in Patients with Irritable Bowel Syndrome

    Directory of Open Access Journals (Sweden)

    Anthony Rodrigues

    2012-01-01

    Full Text Available Generalized hypersensitivity that extends into somatic areas is common in patients with irritable bowel syndrome (IBS. The sensitized state, particularly assessed by experimental methods, is known to persist even during remissions of clinical pain. It was hypothesized that disease-related nociceptive activity in the gut maintains a systemic-sensitized state. The present study evaluated responses to prolonged thermal stimuli maintained at constant temperature or constant pain intensity during stimulation. The effect of topically applied rectal lidocaine on heat sensitivity was also evaluated. The question is whether silencing potential intestinal neural activity (which may not always lead to a conscious pain experience with lidocaine attenuates sensitization of somatic areas. Tests were also performed where lidocaine was applied orally to control for systemic or placebo effects of the drug. The IBS subjects exhibited a greater sensitivity to somatic heat stimuli compared to controls; however, lidocaine had no discernible effect on sensitization in this sample of IBS patients, where most of the individuals did not have clinical pain on the day of testing.

  10. Thermal comfort assessment of buildings

    CERN Document Server

    Carlucci, Salvatore

    2013-01-01

    A number of metrics for assessing human thermal response to climatic conditions have been proposed in scientific literature over the last decades. They aim at describing human thermal perception of the thermal environment to which an individual or a group of people is exposed. More recently, a new type of “discomfort index” has been proposed for describing, in a synthetic way, long-term phenomena. Starting from a systematic review of a number of long-term global discomfort indices, they are then contrasted and compared on a reference case study in order to identify their similarities and differences and strengths and weaknesses. Based on this analysis, a new short-term local discomfort index is proposed for the American Adaptive comfort model. Finally, a new and reliable long-term general discomfort index is presented. It is delivered in three versions and each of them is suitable to be respectively coupled with the Fanger, the European Adaptive and the American Adaptive comfort models.

  11. Self-Assessment of Topic Development in Written Production among High School Students

    Science.gov (United States)

    Oi, Yoko Suganuma

    2014-01-01

    The present study mainly focuses on the topic development in student written production through the consistency between student self-assessment and teacher assessment. In the present study, topic development means "cohesion", "overall organization", and "coherence". It proposes the next hypotheses: (i) Students could…

  12. Influence of human nail etching for the assessment of topical onychomycosis therapies.

    Science.gov (United States)

    Repka, Michael A; Mididoddi, Praveen K; Stodghill, Steven P

    2004-09-10

    The purpose of this investigation was to study the physico-chemical properties of hot-melt extruded films containing ketoconazole and to determine the influence of 'nail etching' on film bioadhesion and drug permeability for the assessment of topical onychomycosis therapies. Hot-melt extrusion (HME) was used to prepare films containing 20% w/w ketoconazole. Ketoconazole 0.125% gel was also prepared using Carbopol 974P NF. Films were processed at a temperature range of 115-120 degrees C utilizing a Killion extruder (KLB-100), and were evaluated for post-extrusion drug content, content uniformity, bioadhesion, thermal behavior and nail drug permeation. The extruded films demonstrated excellent content uniformity and post-processing drug content. Tensile and peel tests were recorded to determine the bioadhesive profiles. In this study, work of adhesion and peak adhesive force determinations using the peel tests provided more sensitive results for evaluating the bioadhesivity of the HME films than the tensile tests. The in vitro permeability profiles have demonstrated, that nail samples treated with an 'etchant' demonstrated a significant increase in drug permeability compared to control. Differential scanning calorimetry (DSC) thermograms indicated that ketoconazole was in solid solution within the HME films. These findings are encouraging for the future design and formulation of novel drug delivery systems for the topical treatment of onychomycosis.

  13. Assessing students' epistemic logic using clause topics during problem comparison

    Science.gov (United States)

    Mateycik, Fran; Sheaffer, Kendra

    2013-01-01

    Physics courses ideally facilitate both students understanding of fundamental physical principles, as well as strengthen students' problem solving repertoire. In this study we look at how students divide and/or aggregate various elements of problem statements and how useful distinct principles and concepts, formulae, and general problem contexts are for pairing problems assigned in the same week. Students in an algebra-based physics course were asked to choose two problems from each of their homework assignments which they found to be most similar. The two problems selected were then explicitly compared and contrasted in writing. The written statements were then divided by clause topics and further categorized into levels of epistemic reasoning. This paper presents the qualitative analysis used and provides observed trends that appear in students' homework responses.

  14. The evaluation of topical anti-inflammatory activity on rat ears subjected to thermal injury.

    Science.gov (United States)

    Bronaugh, R L; Roller, R G; Cargill, R

    1978-10-01

    Topical anti-inflammatory activity of steroidal and non-steroidal agents was assessed on inflammation produced by heat. A burn was produced on the ears of rats and the inflammation was quantitated gravimetrically. Steroidal anti-inflammatory agents were ranked in order of decreasing activity: triamcinolone acetonide, dexamethasone, prednisolone and hydrocortisone acetate. The nonsteroidal agents phenylbutazone and indomethacin were also effective in inhibiting the inflammation. Cholesterol, a steroid devoid of anti-inflammatory activity, was inactive in this test. Hydrocortisone acetate, in particular, appears to be less effective in inhibiting this type of inflammation than inflammation produced by croton oil.

  15. Assessment in Music Education: Relationships between Classroom Practice and Professional Publication Topics

    Science.gov (United States)

    McQuarrie, Sarah H.; Sherwin, Ronald G.

    2013-01-01

    The purpose of this study was to investigate the relationship between actual current assessment practices of elementary music teachers and the assessment topics as published in the literature aimed at those teachers. Specifically, this study sought to: 1) identify the current assessment techniques utilized by elementary music teachers; 2) identify…

  16. Current Challenges in Bioequivalence, Quality, and Novel Assessment Technologies for Topical Products

    DEFF Research Database (Denmark)

    Yacobi, Avraham; Shah, Vinod P; Bashaw, Edward D;

    2014-01-01

    topical products. The methods currently available for assessment of BE were reviewed as well as alternatives and the advantages and disadvantages of each method were considered. Guidance on quality and performance of topical products was reviewed and a framework to categorise existing and alternative......This paper summarises the proceedings of a recent workshop which brought together pharmaceutical scientists and dermatologists from academia, industry and regulatory agencies to discuss current regulatory issues and industry practices for establishing therapeutic bioequivalence (BE) of dermatologic...... of topical bioavailability. The discussion on the BE and clinical equivalence of topical products revealed considerable concerns about the variability present in the current methodologies utilized by the industry and regulatory agencies. It was proposed that academicians, researchers, the pharmaceutical...

  17. Electrical Inspection Oriented Thermal Image Quality Assessment

    Science.gov (United States)

    Lin, Ying; Wang, Menglin; Gong, Xiaojin; Guo, Zhihong; Geng, Yujie; Bai, Demeng

    2017-01-01

    This paper presents an approach to access the quality of thermal images that are specially used in electrical inspection. In this application, no reference images are given for quality assessment. Therefore, we first analyze the characteristics for these thermal images. Then, four quantitative measurements, which are one-dimensional (1D) entropy, two-dimensional (2D) entropy, centrality, and No-Reference Structural Sharpness (NRSS), are investigated to measure the information content, the centrality for objects of interest, and the sharpness of images. Moreover, in order to provide a more intuitive measure for human operators, we assign each image with a discrete rate based on these quantitative measurements via the k-nearest neighbor (KNN) method. The proposed approach has been validated in a dataset composed of 2,336 images. Experiments show that our quality assessment results are consistent with subjective assessment.

  18. Topical glucocorticoid has no antinociceptive or anti-inflammatory effect in thermal injury

    DEFF Research Database (Denmark)

    Pedersen, J L; Møiniche, S; Kehlet, H

    1994-01-01

    injuries were induced with a thermode, which was heated to 49 degrees C for 5 min under standardized pressure. Clobetasol propionate or placebo cream was applied to the skin 1 h before burn injury, immediately after the injury and every 12 h for the next 3 days. Heat pain detection thresholds (HPDT), heat...... pain tolerance (HPT), mechanical pain detection thresholds (MPDT) and the intensity of burn-induced erythema (erythema index, EI) were assessed inside the thermal injury and areas of hyperalgesia to pinprick outside the injury were determined before and regularly for 72 h after the burn injury. Burn...... injury caused a decrease in HPDT, HPT and MPDT, an increase in EI and development of mechanical, secondary hyperalgesia. Clobetasol propionate had no effect on any of the nociceptive or inflammatory variables studied....

  19. Temporal Topic Modeling to Assess Associations between News Trends and Infectious Disease Outbreaks

    Science.gov (United States)

    Ghosh, Saurav; Chakraborty, Prithwish; Nsoesie, Elaine O.; Cohn, Emily; Mekaru, Sumiko R.; Brownstein, John S.; Ramakrishnan, Naren

    2017-01-01

    In retrospective assessments, internet news reports have been shown to capture early reports of unknown infectious disease transmission prior to official laboratory confirmation. In general, media interest and reporting peaks and wanes during the course of an outbreak. In this study, we quantify the extent to which media interest during infectious disease outbreaks is indicative of trends of reported incidence. We introduce an approach that uses supervised temporal topic models to transform large corpora of news articles into temporal topic trends. The key advantages of this approach include: applicability to a wide range of diseases and ability to capture disease dynamics, including seasonality, abrupt peaks and troughs. We evaluated the method using data from multiple infectious disease outbreaks reported in the United States of America (U.S.), China, and India. We demonstrate that temporal topic trends extracted from disease-related news reports successfully capture the dynamics of multiple outbreaks such as whooping cough in U.S. (2012), dengue outbreaks in India (2013) and China (2014). Our observations also suggest that, when news coverage is uniform, efficient modeling of temporal topic trends using time-series regression techniques can estimate disease case counts with increased precision before official reports by health organizations.

  20. Assessment indices for uniform and non-uniform thermal environments

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Different assessment indices for thermal environments were compared and selected for proper assessment of indoor thermal environments.30 subjects reported their overall thermal sensation,thermal comfort,and thermal acceptability in uniform and non-uniform conditions.The results show that these three assessment indices provide equivalent evaluations in uniform environments.However,overall thermal sensation differs from the other two indices and cannot be used as a proper index for the evaluation of non-uniform environments.The relationship between the percentage and the mean vote for each index is established.

  1. Probabilistic assessment of pressurised thermal shocks

    Energy Technology Data Exchange (ETDEWEB)

    Pištora, Vladislav, E-mail: pis@ujv.cz; Pošta, Miroslav; Lauerová, Dana

    2014-04-01

    Rector pressure vessel (RPV) is a key component of all PWR and VVER nuclear power plants (NPPs). Assuring its integrity is therefore of high importance. Due to high neutron fluence the RPV material is embrittled during NPP operation. The embrittled RPV may undergo severe loading during potential events of the type of pressurised thermal shock (PTS), possibly occurring in the NPP. The resistance of RPV against fast fracture has to be proven by comprehensive analyses. In most countries (with exception of the USA), proving RPV integrity is based on the deterministic PTS assessment. In the USA, the “screening criteria” for maximum allowable embrittlement of RPV material, which form part of the USA regulations, are based on the probabilistic PTS assessment. In other countries, probabilistic PTS assessment is performed only at research level or as supplementary to the deterministic PTS assessment for individual RPVs. In this paper, description of complete probabilistic PTS assessment for a VVER 1000 RPV is presented, in particular, both the methodology and the results are attached. The methodology corresponds to the Unified Procedure for Lifetime Assessment of Components and Piping in WWER NPPs, “VERLIFE”, Version 2008. The main parameters entering the analysis, which are treated as statistical distributions, are as follows: -initial value of material reference temperature T{sub 0}, -reference temperature shift ΔT{sub 0} due to neutron fluence, -neutron fluence, -size, shape, position and density of cracks in the RPV wall, -fracture toughness of RPV material (Master Curve concept is used). The first step of the analysis consists in selection of sequences potentially leading to PTS, their grouping, establishing their frequencies, and selecting of representative scenarios within all groups. Modified PSA model is used for this purpose. The second step consists in thermal hydraulic analyses of the representative scenarios, with the goal to prepare input data for the

  2. OCEAN THERMAL ENERGY CONVERSION PROGRAMMATIC ENVIRONMENTAL ASSESSMENT

    Energy Technology Data Exchange (ETDEWEB)

    Sands, M. Dale

    1980-08-01

    Significant achievements in Ocean Thermal Energy Conversion (OTEC) technology have increased the probability of producing OTEC-derived power in this decade with subsequent large-scale commercialization to follow by the turn of the century. Under U.S. Department of Energy funding, Interstate Electronics has prepared an OTEC Programmatic Environmental Assessment (EA) that considers tne development, demonstration, and commercialization of OTEC power systems. The EA considers several tecnnological designs (open cycle and closed cycle), plant configurations (land-based, moored, and plantship), and power usages (baseload electricity and production of ammonia and aluminum). Potencial environmental impacts, health and safety issues, and a status update of international, federal, and state plans and policies, as they may influence OTEC deployments, are included.

  3. Assessing patient satisfaction with cataract surgery under topical anesthesia supplemented by intracameral lidocaine combined with sedation

    Directory of Open Access Journals (Sweden)

    Manuela Bezerril Cipião Fernandes

    2013-12-01

    Full Text Available PURPOSE: Ocular akinesia, the use of anticoagulants, and patient collaboration are some of the factors that must be taken into consideration when choosing the appropriate anesthesia for phacoemulsification cataract surgery. The satisfaction of patients with the use of topical anesthesia and conscious sedation for this procedure has not been enough described in Brazil. Conscious sedation allows patient walk and answer a voice command. To assess the satisfaction, pain, and perioperative hemodynamic alterations of patients subjected to phacoemulsification under conscious sedation and topical anesthesia supplemented with intracameral lidocaine. METHODS: Prospective cohort non-controlled study that included patients treated by the same surgical team over a 70-day period. Sedation was performed with midazolam at a total dose of 3 mg and topical anesthesia with 0.5% proxymetacaine chlorhydrate and 2% lidocaine gel combined with 2% lidocaine by intracameral route. The intraoperative vital parameters, scores based on the Iowa Satisfaction with Anesthesia Scale (ISAS, and the pain visual analog scale (VAS were recorded at several time points after surgery. RESULTS: A total of 106 patients were enroled in study (73.6% female, the mean age was 65.9 years. The surgical procedures lasted 11.2 minutes on average. The hemodynamic parameters did not exhibit significant changes at any of the investigated time points. The average ISAS score was 2.67 immediately after surgery and 2.99 eight hours after the surgery; this increase was statistically significant (p<0.0001. More than two-thirds (68.9% of the participants (73 patients did not report any pain in the transoperative period, and 98.1% of patients denied the occurrence of pain after surgery. CONCLUSIONS: Patients that received topical anesthesia supplemented by intracameral lidocaine combined with sedation for phacoemulsification cataract surgery reported adequate level of satisfaction with the anesthetic

  4. Underground Coal Thermal Treatment: Task 6 Topical Report, Utah Clean Coal Program

    Energy Technology Data Exchange (ETDEWEB)

    Smith, P.J.; Deo, M.; Edding, E.G.; Hradisky, M.; Kelly, K.E.; Krumm, R.; Sarofim, Adel; Wang, D.

    2014-08-15

    The long-term objective of this task is to develop a transformational energy production technology by in- situ thermal treatment of a coal seam for the production of substitute natural gas and/or liquid transportation fuels while leaving much of the coal’s carbon in the ground. This process converts coal to a high-efficiency, low-greenhouse gas (GHG) emitting fuel. It holds the potential of providing environmentally acceptable access to previously unusable coal resources. This task focused on three areas: Experimental. The Underground Coal Thermal Treatment (UCTT) team focused on experiments at two scales, bench-top and slightly larger, to develop data to understand the feasibility of a UCTT process as well as to develop validation/uncertainty quantification (V/UQ) data for the simulation team. Simulation. The investigators completed development of High Performance Computing (HPC) simulations of UCTT. This built on our simulation developments over the course of the task and included the application of Computational Fluid Dynamics (CFD)- based tools to perform HPC simulations of a realistically sized domain representative of an actual coal field located in Utah. CO2 storage. In order to help determine the amount of CO2 that can be sequestered in a coal formation that has undergone UCTT, adsorption isotherms were performed on coals treated to 325, 450, and 600°C with slow heating rates. Raw material was sourced from the Sufco (Utah), Carlinville (Illinois), and North Antelope (Wyoming) mines. The study indicated that adsorptive capacity for the coals increased with treatment temperature and that coals treated to 325°C showed less or similar capacity to the untreated coals.

  5. Bone assessment via thermal photoacoustic measurements

    Science.gov (United States)

    Feng, Ting; Kozloff, Kenneth M.; Hsiao, Yi-Sing; Tian, Chao; Perosky, Joseph; Du, Sidan; Yuan, Jie; Deng, Cheri X.; Wang, Xueding

    2015-03-01

    The feasibility of an innovative biomedical diagnostic technique, thermal photoacoustic (TPA) measurement, for nonionizing and non-invasive assessment of bone health is investigated. Unlike conventional photoacoustic PA methods which are mostly focused on the measurement of absolute signal intensity, TPA targets the change in PA signal intensity as a function of the sample temperature, i.e. the temperature dependent Grueneisen parameter which is closely relevant to the chemical and molecular properties in the sample. Based on the differentiation measurement, the results from TPA technique is less susceptible to the variations associated with sample and system, and could be quantified with improved accurately. Due to the fact that the PA signal intensity from organic components such as blood changes faster than that from non-organic mineral under the same modulation of temperature, TPA measurement is able to objectively evaluate bone mineral density (BMD) and its loss as a result of osteoporosis. In an experiment on well established rat models of bone loss and preservation, PA measurements of rat tibia bones were conducted over a temperature range from 370 C to 440 C. The slope of PA signal intensity verses temperature was quantified for each specimen. The comparison among three groups of specimens with different BMD shows that bones with lower BMD have higher slopes, demonstrating the potential of the proposed TPA technique in future clinical management of osteoporosis.

  6. Relationship between Usefulness Assessments and Perceptions of Work Task Complexity and Search Topic Specificity: An Exploratory Study

    DEFF Research Database (Denmark)

    Ingwersen, Peter; Wang, Peiling

    2012-01-01

    This research investigates the relations between the usefulness assessments of retrieved documents and the perceptions of task complexity and search topic specificity. Twenty-three academic researchers submitted 65 real task-based information search topics. These task topics were searched...... in an integrated document collection consisting of full text research articles in PDFs, abstracts, and bibliographic records (the iSearch Test Collection in Physics). The search results were provided to the researchers who, as task performers, made assessments of usefulness using a four-point sale (highly, fairly...... highly complex tasks tend to associate with search topics of high specificity. Although bibliographic records show better precisions than full text PDF documents, the latter contributed more useful documents. Suggestions are made for further studies in naturalist IR experiments....

  7. The Efficacy of Topic Familiarity on Oral Presentation: Extensive Speaking Assessment Task of Iranian EFL Learners in TBLT

    OpenAIRE

    2015-01-01

    In order to communicate effectively, EFL learners require considering a variety of linguistic, contextual, cultural, and interactional aspects of complex communicative process of English learning along with receiving appropriate tasks. The tasks of speaking assessment are of paramount importance in EFL settings. The current study focused on one main factor that has been proposed in TBLT, i.e. topic familiarity to investigate the effect of topic familiarity on EFL oral presentations. The parti...

  8. Journal “Topics in Early Childhood Special Education”: assessment of the periodical and articles

    Directory of Open Access Journals (Sweden)

    Paulo Celso Pereira

    2008-12-01

    Full Text Available Journals have the purpose of dissemination and communication of scientific knowledge. As a vehicle to the dissemination of scientific productions, it is necessary the periodical assessment to evaluate the quality of research: accuracy, reliability and seriousness. The objective of this study is to assess the journal Topics in Early Childhood Special Education, considering for the analysis the whole journal and the formal and the contents aspects of all articles. The analysis revealed that the periodical satisfactorily fulfills the normalization criterion, the authors’ instruction criterion and the articles assessment criterion. However, it was identified the need for major accuracy in the bibliographic legend that should appear on all pages of articles. Regarding the analysis of the articles it was observed the lack of keywords and a wide variety of information in the abstracts, which they were sometimes not related to the key aspects of the research. All authors and institutions are from United States of America and the type of study most published it was the research report. The participants’ characterization indicated that the journal broachs different types of special needs, but there is more studies about autism. The study data confirm the journal purpose that is providing relevant and current information on all aspects of early education for children with special needs, including their families. It was pointed the need for more articles from other countries beyond the North American continent, including the participation of researcher from other countries. Additionally, the model used for the journal assessment showed to be effective in providing data quality, reliability and accuracy of the whole periodical and the studies that it was published in the journal.

  9. Assessment of topical versus oral ivermectin as a treatment for head lice.

    Science.gov (United States)

    Ahmad, Hesham M; Abdel-Azim, Eman S; Abdel-Aziz, Rasha T

    2014-01-01

    Many medications are available for treatment of pediculosis capitis including ivermectin. Our aim is to compare the efficacy and safety of topical versus oral ivermectin in treatment of pediculosis capitis. Sixty-two patients with proved head lice infestation were included and divided into group I (31 patients; received single topical application of 1% ivermectin) and group II (31 patients; received single dose of oral ivermectin). Treatment was repeated after 1 week for nonresponders. At 1 week after treatment, the eradication rates and improvement of pruritus were significantly higher among patients who received topical than oral ivermectin. When a second treatment, topical or oral, was given to nonresponders, the cure rates of infestation and pruritus was 100% and 97% among patients treated with topical and oral ivermectin, respectively with no significant difference between the two groups. This study suggests that both topical and oral ivermectin demonstrate high efficacy and tolerability in treatment of pediculosis capitis. However, a single treatment with topical ivermectin provides significantly higher cure of infestation and faster relief of pruritus than oral ivermectin. In addition, whether topical or oral ivermectin is used to treat head lice, a second dose is required in some cases to ensure complete eradication.

  10. The Efficacy of Topic Familiarity on Oral Presentation: Extensive Speaking Assessment Task of Iranian EFL Learners in TBLT

    Directory of Open Access Journals (Sweden)

    Seyyed Ali Kazemi

    2015-05-01

    Full Text Available In order to communicate effectively, EFL learners require considering a variety of linguistic, contextual, cultural, and interactional aspects of complex communicative process of English learning along with receiving appropriate tasks. The tasks of speaking assessment are of paramount importance in EFL settings. The current study focused on one main factor that has been proposed in TBLT, i.e. topic familiarity to investigate the effect of topic familiarity on EFL oral presentations. The participants were 30 female intermediate participants ranged from 14 to 18 year old studying at one English language institute in Shiraz, Iran. A sample model of Oxford Placement Test was used to determine the participants' level of English proficiency. Then, the participants were asked to give impromptu presentations about unfamiliar topics. Their oral presentations were evaluated as pre-tests. In order to administer post-tests participants were asked to work on a new topic for the subsequent session. All oral presentations were evaluated through Brown and Abeywickrama (2010 checklist. Using SPSS software, paired- sample t-test was used to analyze the collected data. The results indicated that there was significant difference between mean scores of pre-tests and post-tests. The findings of this study indicate that topic familiarity has an influence on learners' oral presentations.Keywords: task-based language teaching (TBLT, topic familiarity, extensive speaking task, oral presentation 

  11. Functional assessment and treatment of perseverative speech about restricted topics in an adolescent with Asperger syndrome.

    Science.gov (United States)

    Fisher, Wayne W; Rodriguez, Nicole M; Owen, Todd M

    2013-01-01

    A functional analysis showed that a 14-year-old boy with Asperger syndrome displayed perseverative speech (or "restricted interests") reinforced by attention. To promote appropriate speech in a turn-taking format, we implemented differential reinforcement (DR) of nonperseverative speech and DR of on-topic speech within a multiple schedule with stimuli that signaled the contingencies in effect and who was to select the topic. Both treatments reduced perseverative speech, but only DR of on-topic speech increased appropriate turn taking during conversation. Treatment effects were maintained when implemented by family members and novel therapists.

  12. Development and in vitro assessment of alginate bilayer films containing the olive compound hydroxytyrosol as an alternative for topical chemotherapy.

    Science.gov (United States)

    Ng, Shiow-Fern; Tan, Say-Lee

    2015-11-30

    Topical chemotherapy is the application of cancer drugs directly onto the skin, which has become a standard treatment for basal cell carcinoma. Due to the promising results in the treatment of skin cancer, topical chemotherapy has recently been applied to breast cancer patients because some breast cancer tissues are only superficial. Hydroxytyrosol, a phenolic compound from olives that is present in high amounts in Hidrox(®) olive extract, has been shown to have a protective effect on normal cells and selective antitumor activities on cancerous cells. The aims of the present study were to develop an alginate bilayer film containing Hidrox(®) and to investigate its potential use as a topical chemotherapeutic agent. Alginate films were characterized for swelling and for physical, thermal, rheological, and mechanical properties. Drug content uniformity and in vitro drug release tests were also investigated. The alginate bilayer films containing Hidrox(®), HB2, showed controlled release of hydroxytyrosol at a flux of 0.094±0.009 mg/cm(2)/h. The results of the cytotoxic assay showed that the HB2 films were dose-dependent and could significantly reduce the growth of breast cancer cells (MCF-7) at 150 μg/mL for a cell viability of 29.34±4.64%. In conclusion, an alginate bilayer film containing Hidrox(®) can be a potential alternative for topical chemotherapeutic agent for skin and breast cancer treatment.

  13. The topical use of non-thermal dielectric barrier discharge (DBD): nitric oxide related effects on human skin.

    Science.gov (United States)

    Heuer, Kiara; Hoffmanns, Martin A; Demir, Erhan; Baldus, Sabrina; Volkmar, Christine M; Röhle, Mirco; Fuchs, Paul C; Awakowicz, Peter; Suschek, Christoph V; Opländer, Christian

    2015-01-30

    Dielectric barrier discharge (DBD) devices generate air plasma above the skin containing active and reactive species including nitric oxide (NO). Since NO plays an essential role in skin physiology, a topical application of NO by plasma may be useful in the treatment of skin infections, impaired microcirculation and wound healing. Thus, after safety assessments of plasma treatment using human skin specimen and substitutes, NO-penetration through the epidermis, the loading of skin tissue with NO-derivates in vitro and the effects on human skin in vivo were determined. After the plasma treatment (0-60 min) of skin specimen or reconstructed epidermis no damaging effects were found (TUNEL/MTT). By Franz diffusion cell experiments plasma-induced NO penetration through epidermis and dermal enrichment with NO related species (nitrite 6-fold, nitrate 7-fold, nitrosothiols 30-fold) were observed. Furthermore, skin surface was acidified (~pH 2.7) by plasma treatment (90 s). Plasma application on the forearms of volunteers increased microcirculation fourfold in 1-2 mm and twofold in 6-8 mm depth in the treated skin areas. Regarding the NO-loading effects, skin acidification and increase in dermal microcirculation, plasma devices represent promising tools against chronic/infected wounds. However, efficacy of plasma treatment needs to be quantified in further studies and clinical trials.

  14. 5-Megawatt solar-thermal test facility: environmental assessment

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-01-30

    An Environmental Assessment of the 5 Megawatt Solar Thermal Test Facility (STTF) is presented. The STTF is located at Albuquerque, New Mexico. The facility will have the capability for testing scale models of major subsystems comprising a solar thermal electrical power plant. The STTF capabilities will include testing a solar energy collector subsystem comprised of heliostat arrays, a receiver subsystem which consists of a boiler/superheater in which a working fluid is heated, and a thermal storage subsystem which includes tanks of high heat capacity material which stores thermal energy for subsequent use. The STTF will include a 200-foot receiver tower on which experimental receivers will be mounted. The Environmental Assessment describes the proposed STTF, its anticipated benefits, and the environment affected. It also evaluates the potential environmental impacts associated with STTF construction and operation.

  15. The Systems Analysis and Design Course: An Educators' Assessment of the Importance and Coverage of Topics

    Science.gov (United States)

    Guidry, Brandi N.; Stevens, David P.; Totaro, Michael W.

    2011-01-01

    This study examines instructors' perceptions regarding the skills and topics that are most important in the teaching of a Systems Analysis and Design ("SAD") course and the class time devoted to each. A large number of Information Systems ("IS") educators at AACSB accredited schools across the United States were surveyed.…

  16. 75 FR 54403 - U.S. National Climate Assessment Objectives, Proposed Topics, and Next Steps

    Science.gov (United States)

    2010-09-07

    ... described above. It has been developed within the Interagency National Climate Assessment (INCA) Task Force... following issue areas may be used by the Interagency National Climate Assessment (INCA) Task Force and the... Assessment. Issue Areas: The INCA Task Force has identified the need for discussion on important...

  17. Mathematical Safety Assessment Approaches for Thermal Power Plants

    Directory of Open Access Journals (Sweden)

    Zong-Xiao Yang

    2014-01-01

    Full Text Available How to use system analysis methods to identify the hazards in the industrialized process, working environment, and production management for complex industrial processes, such as thermal power plants, is one of the challenges in the systems engineering. A mathematical system safety assessment model is proposed for thermal power plants in this paper by integrating fuzzy analytical hierarchy process, set pair analysis, and system functionality analysis. In the basis of those, the key factors influencing the thermal power plant safety are analyzed. The influence factors are determined based on fuzzy analytical hierarchy process. The connection degree among the factors is obtained by set pair analysis. The system safety preponderant function is constructed through system functionality analysis for inherence properties and nonlinear influence. The decision analysis system is developed by using active server page technology, web resource integration, and cross-platform capabilities for applications to the industrialized process. The availability of proposed safety assessment approach is verified by using an actual thermal power plant, which has improved the enforceability and predictability in enterprise safety assessment.

  18. Comparative diffusion assay to assess efficacy of topical antimicrobial agents against Pseudomonas aeruginosa in burns care

    Directory of Open Access Journals (Sweden)

    Godreuil Sylvain

    2011-06-01

    Full Text Available Abstract Background Severely burned patients may develop life-threatening nosocomial infections due to Pseudomonas aeruginosa, which can exhibit a high-level of resistance to antimicrobial drugs and has a propensity to cause nosocomial outbreaks. Antiseptic and topical antimicrobial compounds constitute major resources for burns care but in vitro testing of their activity is not performed in practice. Results In our burn unit, a P. aeruginosa clone multiresistant to antibiotics colonized or infected 26 patients over a 2-year period. This resident clone was characterized by PCR based on ERIC sequences. We investigated the susceptibility of the resident clone to silver sulphadiazine and to the main topical antimicrobial agents currently used in the burn unit. We proposed an optimized diffusion assay used for comparative analysis of P. aeruginosa strains. The resident clone displayed lower susceptibility to silver sulphadiazine and cerium silver sulphadiazine than strains unrelated to the resident clone in the unit or unrelated to the burn unit. Conclusions The diffusion assay developed herein detects differences in behaviour against antimicrobials between tested strains and a reference population. The method could be proposed for use in semi-routine practice of medical microbiology.

  19. Retention Assessment of Core Operations Management Topics for Business Administration Students

    Science.gov (United States)

    Koppel, Nicole B.; Hollister, Kimberly Killmer

    2009-01-01

    To meet the new AACSB International standards regarding retention assessment and adequately determine "if and what students are learning," this research presents a framework within which expected learning outcomes and specific learning are assessed. This paper presents the framework and describes how the process can be implemented with…

  20. Two Stage Assessment of Thermal Hazard in An Underground Mine

    Science.gov (United States)

    Drenda, Jan; Sułkowski, Józef; Pach, Grzegorz; Różański, Zenon; Wrona, Paweł

    2016-06-01

    The results of research into the application of selected thermal indices of men's work and climate indices in a two stage assessment of climatic work conditions in underground mines have been presented in this article. The difference between these two kinds of indices was pointed out during the project entitled "The recruiting requirements for miners working in hot underground mine environments". The project was coordinated by The Institute of Mining Technologies at Silesian University of Technology. It was a part of a Polish strategic project: "Improvement of safety in mines" being financed by the National Centre of Research and Development. Climate indices are based only on physical parameters of air and their measurements. Thermal indices include additional factors which are strictly connected with work, e.g. thermal resistance of clothing, kind of work etc. Special emphasis has been put on the following indices - substitute Silesian temperature (TS) which is considered as the climatic index, and the thermal discomfort index (δ) which belongs to the thermal indices group. The possibility of the two stage application of these indices has been taken into consideration (preliminary and detailed estimation). Based on the examples it was proved that by the application of thermal hazard (detailed estimation) it is possible to avoid the use of additional technical solutions which would be necessary to reduce thermal hazard in particular work places according to the climate index. The threshold limit value for TS has been set, based on these results. It was shown that below TS = 24°C it is not necessary to perform detailed estimation.

  1. An assessment methodology for thermal energy storage evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D.R.; Dirks, J.A.; Drost, M.K.; Spanner, G.E.; Williams, T.A.

    1987-11-01

    This report documents an assessment methodology for evaluating the cost, performance, and overall economic feasibility of thermal energy storage (TES) concepts. The methodology was developed by Thermal Energy Storage Evaluation Program personnel at Pacific Northwest Laboratory (PNL) for use by PNL and other TES concept evaluators. The methodology is generically applicable to all TES concepts; however, specific analyses may require additional or more detailed definition of the ground rules, assumptions, and analytical approach. The overall objective of the assessment methodology is to assist in preparing equitable and proper evaluations of TES concepts that will allow developers and end-users to make valid decisions about research and development (R and D) and implementation. The methodology meets this objective by establishing standard approaches, ground rules, assumptions, and definitions that are analytically correct and can be consistently applied by concept evaluators. 15 refs., 4 figs., 13 tabs.

  2. Validity of Thermal Ramping Assays Used to Assess Thermal Tolerance in Arthropods

    DEFF Research Database (Denmark)

    Overgaard, Johannes; Kristensen, Torsten Nygård; Sørensen, Jesper Givskov

    2012-01-01

    are useful assays for small insects because they incorporate an ecologically relevant gradual temperature change. However, recent model-based papers have suggested that estimates of thermal resistance may be strongly confounded by simultaneous starvation and dehydration stress. In the present study we....... On the basis of our results we discuss the assumptions used in recent model papers and present arguments as to why the ramping assay is both a valid and ecologically relevant way to measure thermal resistance in insects......Proper assessment of environmental resistance of animals is critical for the ability of researchers to understand how variation in environmental conditions influence population and species abundance. This is also the case for studies of upper thermal limits in insects, where researchers studying...

  3. Thermal Cycling Assessment of Steel-Based Thermal Barrier Coatings for Al Protection

    Science.gov (United States)

    Poirier, Dominique; Lamarre, Jean-Michel; Legoux, Jean-Gabriel

    2015-01-01

    There is a strong interest from the transportation industry to achieve vehicle weight reduction through the replacement of steel components by aluminum parts. For some applications, aluminum requires protective coatings due to its limited wear and lower temperature resistance compared to steel. The objective of this study was to assess the potential of amorphous-type plasma-sprayed steel coatings and conventional arc-sprayed steel coatings as thermal barrier coatings, mainly through the evaluation of their spalling resistance under thermal cycling. The microstructures of the different coatings were first compared via SEM. The amorphicity of the coatings produced via plasma spraying of specialized alloyed steel and the crystalline phases of the conventional arc-sprayed steel coatings were confirmed through x-ray diffraction. The thermal diffusivity of all coatings produced was measured to be about a third of that of bulk stainless steel. Conventional arc-sprayed steel coatings typically offered better spalling resistance under thermal cycling than steel-based amorphous coatings due probably to their higher initial bond strength. However, the presence of vertical cracks in the steel-based amorphous coatings was found to have a beneficial effect on their thermal cycling resistance. The amorphous plasma-sprayed steel coatings presented indications of recrystallization after their exposure to high temperature.

  4. Quantitative assessment of pain-related thermal dysfunction through clinical digital infrared thermal imaging

    Directory of Open Access Journals (Sweden)

    Frize Monique

    2004-06-01

    Full Text Available Abstract Background The skin temperature distribution of a healthy human body exhibits a contralateral symmetry. Some nociceptive and most neuropathic pain pathologies are associated with an alteration of the thermal distribution of the human body. Since the dissipation of heat through the skin occurs for the most part in the form of infrared radiation, infrared thermography is the method of choice to study the physiology of thermoregulation and the thermal dysfunction associated with pain. Assessing thermograms is a complex and subjective task that can be greatly facilitated by computerised techniques. Methods This paper presents techniques for automated computerised assessment of thermal images of pain, in order to facilitate the physician's decision making. First, the thermal images are pre-processed to reduce the noise introduced during the initial acquisition and to extract the irrelevant background. Then, potential regions of interest are identified using fixed dermatomal subdivisions of the body, isothermal analysis and segmentation techniques. Finally, we assess the degree of asymmetry between contralateral regions of interest using statistical computations and distance measures between comparable regions. Results The wavelet domain-based Poisson noise removal techniques compared favourably against Wiener and other wavelet-based denoising methods, when qualitative criteria were used. It was shown to improve slightly the subsequent analysis. The automated background removal technique based on thresholding and morphological operations was successful for both noisy and denoised images with a correct removal rate of 85% of the images in the database. The automation of the regions of interest (ROIs delimitation process was achieved successfully for images with a good contralateral symmetry. Isothermal division complemented well the fixed ROIs division based on dermatomes, giving a more accurate map of potentially abnormal regions. The measure

  5. Strategies for microwave thermal treatment planning, navigation, and assessment

    Science.gov (United States)

    Ryan, Thomas P.

    2011-03-01

    Thermal treatment is commonly performed interstitially in either surgical or percutaneous procedures, using microwave antenna sources at 915 or 2540 MHz. There are a number of tools or aids as well as challenges for clinicians performing these procedures in the course of patient treatment. These challenges will be present whether the procedure is surgical, laparoscopic, or percutaneous, and include treatment planning, image guidance, navigation, coregistration in 3D, and treatment assessment. Treatment planning has been used historically in hyperthermia for microwave antenna arrays, but has yet to be properly applied in thermal ablation. Image assessment of thermal treatment is not typically performed in real time, although these tools will provide the clinician with further information to understand the extent of treatment and whether further treatment is needed. 3D imaging is available, but not coregistered to patient space. Navigation has been used in many medical specialties, but is also not in the clinician's toolbox in thermal treatment. Although treatment planning will lay out the skin entry and trajectory for each antenna placed, subsequently, each antenna needs to be tracked to accurately show placement in the patient and overlaid in patient space, along with the tumor target location. Some patient treatments may consist of multiple, but sequential single placements of an antenna, and guidance is even more critical to track positions and plan for the next insertion. Lastly, real-time image assessment will show the extent and shape of the coagulated lesion and which targets may have been undertreated. If used synchronously in arrays, MW power steering may also aid in filling in the ablation as the treatment progresses. This paper will analyze the present state-of-the art as well as a strategy to incorporate the various facets of planning, guidance, and assessment of treatment. The integration of thermal treatment planning, navigation and guidance, robotics

  6. Thermal Comfort Assessment: A Case Study at Malaysian Automotive Industry

    Directory of Open Access Journals (Sweden)

    A. R. Ismail

    2009-01-01

    Full Text Available Problem statement: Thermal comfort has a great influence on the productivity and satisfaction of indoor building occupants. The exposure to excessive heat during work may cause discomfort and contributed to low productivity among workers. Malaysia known with its hot and humid weather where in most of the survey study published indicated that workers in Malaysia automotive industries had exposed to excessive temperature while working. The study investigated the thermal comfort level experienced by workers at Malaysian automotive industry. Approach: The study had been conducted at one automotive parts assembly factory in Malaysia. The human subjects for the study constitute operators at tire receiving section of the factory. The environment examined was the relative humidity (%, WBGT, air temperature and radiant temperature (°C of the surrounding workstation area. The environmental factors were measured using Babuc apparatus, which is capable to measure simultaneously those mentioned environmental factors. The time series data of fluctuating level of factors were plotted to identify the significant changes of factors. Then thermal comfort of the workers was assessed by using ASHRAE thermal sensation scale by using Predicted Mean Vote (PMV. Further Predicted Percentage Dissatisfied (PPD was used to estimate the thermal comfort satisfaction of the occupant. Finally the PPD versus PMV were plotted to present the thermal comfort scenario of workers involved in related workstation. Results: The trend of relative humidity curve from the graph also indicated the increasing level of discomfort. The radiant temperature observed seems consistent during the study while there was decreasing of WBGT start from afternoon due to the rain. The study revealed that the PPD value of 54% of the workers population at the workstation are likely to be satisfied with thermal comfort at this station while the PMV index from ASHRAE indicated the value 1

  7. Objective assessment of biomagnetic devices and alternative clinical therapies using infrared thermal imaging

    Science.gov (United States)

    Rockley, Graham J.

    2001-03-01

    The overwhelming introduction of magnetic devices and other alternative therapies into the health care market prompts the need for objective evaluation of these techniques through the use of infrared thermal imaging. Many of these therapies are reported to promote the stimulation of blood flow or the relief of pain conditions. Infrared imaging is an efficient tool to assess such changes in the physiological state. Therefore, a thermal imager can help document and substantiate whether these therapies are in fact providing an effective change to the local circulation. Thermal images may also indicate whether the change is temporary or sustained. As a specific case example, preliminary findings will be presented concerning the use of magnets and the effect they have on peripheral circulation. This will include a discussion of the recommended protocols for this type of infrared testing. This test model can be applied to the evaluation of other devices and therapeutic procedures which are reputed to affect circulation such as electro acupuncture, orthopedic footwear and topical ointments designed to relieve pain or inflammation.

  8. Reliability assessment on interfacial failure of thermal barrier coatings

    Science.gov (United States)

    Guo, Jin-Wei; Yang, Li; Zhou, Yi-Chun; He, Li-Min; Zhu, Wang; Cai, Can-Ying; Lu, Chun-Sheng

    2016-10-01

    Thermal barrier coatings (TBCs) usually exhibit an uncertain lifetime owing to their scattering mechanical properties and severe service conditions. To consider these uncertainties, a reliability assessment method is proposed based on failure probability analysis. First, a limit state equation is established to demarcate the boundary between failure and safe regions, and then the failure probability is calculated by the integration of a probability density function in the failure area according to the first- or second-order moment. It is shown that the parameters related to interfacial failure follow a Weibull distribution in two types of TBC. The interfacial failure of TBCs is significantly affected by the thermal mismatch of material properties and the temperature drop in service.

  9. Reliability assessment on interfacial failure of thermal barrier coatings

    Institute of Scientific and Technical Information of China (English)

    Jin-Wei Guo; Li Yang; Yi-Chun Zhou; Li-Min He; Wang Zhu; Can-Ying Cai; Chun-Sheng Lu

    2016-01-01

    Thermal barrier coatings (TBCs) usually exhibit an uncertain lifetime owing to their scattering mechanical properties and severe service conditions. To consider these uncertainties, a reliability assessment method is proposed based on failure probability analysis. First, a limit state equa-tion is established to demarcate the boundary between failure and safe regions, and then the failure probability is calculated by the integration of a probability density function in the failure area according to the first-or second-order moment. It is shown that the parameters related to interfacial failure follow a Weibull distribution in two types of TBC. The inter-facial failure of TBCs is significantly affected by the thermal mismatch of material properties and the temperature drop in service.

  10. A comparison of techniques to assess skin blanching following the topical application of glucocorticoids.

    Science.gov (United States)

    Noon, J P; Evans, C E; Haynes, W G; Webb, D J; Walker, B R

    1996-05-01

    Glucocorticoid-induced dermal blanching provides a useful research tool to study steroid potency and sensitivity. Conventional measurement of the intensity of blanching relies on subjective assessment by a trained observer using a visual score. Several objective techniques have recently been reported to detect skin blanching, but their sensitivity has not been compared previously with subjective visual recordings. In this report we aimed to establish whether objective methods offer sufficient sensitivity to be employed in epidemiological studies of glucocorticoid responsiveness. In healthy subjects we applied beclomethasone dipropionate at three concentrations (1, 10 and 100 micrograms/ml) under an occluded dressing overnight. The following morning we measured blanching using a visual score, laser Doppler velocimetry with the MBF 3D monitor (Moor Instruments Ltd, U.K.) and a perfusion imager (Lisca, Sweden), and reflectance spectrophotometry with the Dia-Stron 'erythemameter'. Using the visual score, blanching was detected at all concentrations of steroid. Neither laser Doppler instrument detected vasoconstriction at any concentration. By contrast, the reflectance spectrophotometer successfully recorded blanching at 10 and 100 micrograms/ml, but not at 1 microgram/ml. We conclude that laser Doppler instruments, including the novel scanning perfusion imager, do not detect glucocorticoid-induced skin blanching, perhaps because it reflects venular rather than arteriolar vasoconstriction. By contrast, the Dia-Stron reflectance spectrophotometer has sufficient sensitivity to be used as an alternative to visual assessment in epidemiological studies of human glucocorticoid-induced dermal blanching.

  11. Assessment of in vitro methodologies to determine topical and transdermal delivery of the flavonoid quercetin

    Directory of Open Access Journals (Sweden)

    Fabiana Testa Moura de Carvalho Vicentini

    2009-06-01

    Full Text Available To be effective against the oxidative damages induced by UVB irradiation in the skin, the drug needs to release from the formulation in which it was incorporated and reach the skin layers where the ROS are generated. Thus, it is very important the development of a robust and sensitive methodology to extract and quantify in different skin layers the antioxidant agent delivered from topical formulations. Therefore, in the present work suitable methods to extract and quantify quercetin in skin samples and receptor phase after in vitro penetration studies were developed. The results demonstrated that the recovery from two different layers of skin, the SC and [E+D], using two different methods of quantification (DPPH• assay and HPLC, respectively, was 93.8 % when the quercetin spiked dose was 50 µg/mL, 100.4 % when it was 100 µg/mL and 89.9 % for 250 µg/mL and the average recovery of the quercetin extraction from receptor phase when dichloromethane was used as extractor solvent was 96%. These results demonstrate that the described methods have a potential application to in vitro skin penetration studies of quercetin, since it showed to be accurate and sensitive.Para ser efetiva contra os danos oxidativos induzidos pela radiação UVB na pele, é necessário que o ativo seja liberado da formulação na qual foi incorporado e alcance as camadas da pele onde são geradas as EROS. Desta forma, torna-se de grande importância o desenvolvimento de métodos eficazes e sensíveis para extrair e quantificar, nas diferentes camadas de pele, o agente antioxidante liberado de formulações tópicas. No presente trabalho foram desenvolvidos métodos adequados para extrair e quantificar a quercetina em amostras de pele e na fase receptora após estudos de penetração cutânea in vitro. Os resultados demonstraram que a recuperação das camadas de pele, EC e [E+D], quando do uso de duas diferentes metodologias de quantificação (ensaio de DPPH• e CLAE

  12. Bimatoprost Topical

    Science.gov (United States)

    Topical bimatoprost is used to treat hypotrichosis (less than the normal amount of hair) of the eyelashes by promoting ... growth of longer, thicker, and darker lashes. Topical bimatoprost is in a class of medications called prostaglandin ...

  13. In vivo multiphoton imaging of human skin: assessment of topical corticosteroid-induced epidermis atrophy and depigmentation

    Science.gov (United States)

    Ait El Madani, Hassan; Tancrède-Bohin, Emmanuelle; Bensussan, Armand; Colonna, Anne; Dupuy, Alain; Bagot, Martine; Pena, Ana-Maria

    2012-02-01

    Multiphoton microscopy has emerged in the past decade as a promising tool for noninvasive skin imaging. Our aim was to evaluate the potential of multiphoton microscopy to detect topical corticosteroids side effects within the epidermis and to provide new insights into their dynamics. Healthy volunteers were topically treated with clobetasol propionate on a small region of their forearms under overnight occlusion for three weeks. The treated region of each patient was investigated at D0, D7, D15, D22 (end of the treatment), and D60. Our study shows that multiphoton microscopy allows for the detection of corticoid-induced epidermis modifications: thinning of stratum corneum compactum and epidermis, decrease of keratinocytes size, and changes in their morphology from D7 to D22. We also show that multiphoton microscopy enables in vivo three-dimensional (3-D) quantitative assessment of melanin content. We observe that melanin density decreases during treatment and almost completely disappears at D22. Moreover, these alterations are reversible as they are no longer present at D60. Our study demonstrates that multiphoton microscopy is a convenient and powerful tool for noninvasive 3-D dynamical studies of skin integrity and pigmentation.

  14. Solar-parabolic dish-Stirling-engine-system module. Task 1: Topical report, market assessment/conceptual design

    Energy Technology Data Exchange (ETDEWEB)

    1982-11-30

    The major activities reported are: a market study to identify an early market for a dish-Stirling module and assess its commercial potential; preparation of a conceptual system and subsystem design to address this market; and preparation of an early sales implementation plan. A study of the reliability of protection from the effects of walk-off, wherein the sun's image leaves the receiver if the dish is not tracking, is appended, along with an optical analysis and structural analysis. Also appended are the relationship between PURPA and solar thermal energy development and electric utility pricing rationale. (LEW)

  15. Topical gel formulation and stability assessment of platelet lysate based on turbidimetric method

    Directory of Open Access Journals (Sweden)

    Soliman Mohammadi Samani

    2015-06-01

    Full Text Available Platelet-rich growth factors have attracted attentions of scientists and clinical practitioners who are involved in wound healing and regenerative medicine extensively, according to their unprecedented potential of promoting and catalyzing healing process. Platelet-rich growth factors are cost-benefit, available and more stable than recombinant human growth factors. These appealing characteristics have converted PRGF to one of the popular candidates for treatment of variety of wounds. According to these valuable properties, we decided to formulate and assess the effect of different excipients on the stability of such valuable protein based formulations. Different excipients have been chosen according to their effective ness on the stability of proteins and their application in other similar formulations. The stabilizing effect of excipients was evaluated by measuring heat-induced aggregation of growth factors by turbidimetric assay. Glycerol, glycine and dextrose were chosen as stabilizing excipients for these formulations. The results show that dextrose has more stabilizing effect on prevention of heat induced aggregation of the platelet lysate growth factors than glycerol and glycine. All of the formulations also contained antioxidant, chelating agents, preservative and carbopol934 in order to form appropriate gel.

  16. 76 FR 41217 - Technical Inputs and Assessment Capacity on Topics Related to 2013 U.S. National Climate Assessment

    Science.gov (United States)

    2011-07-13

    ... change and the natural environment, agriculture, energy production and use, ] land and water resources... as they relate to the value of climate and global change information for decision making. Managing... assessment experience, and current role in the climate/global change arena. Sponsoring organization(s),...

  17. The Universal Thermal Climate Index UTCI compared to ergonomics standards for assessing the thermal environment.

    Science.gov (United States)

    Bröde, Peter; Błazejczyk, Krzysztof; Fiala, Dusan; Havenith, George; Holmér, Ingvar; Jendritzky, Gerd; Kuklane, Kalev; Kampmann, Bernhard

    2013-01-01

    The growing need for valid assessment procedures of the outdoor thermal environment in the fields of public weather services, public health systems, urban planning, tourism & recreation and climate impact research raised the idea to develop the Universal Thermal Climate Index UTCI based on the most recent scientific progress both in thermo-physiology and in heat exchange theory. Following extensive validation of accessible models of human thermoregulation, the advanced multi-node 'Fiala' model was selected to form the basis of UTCI. This model was coupled with an adaptive clothing model which considers clothing habits by the general urban population and behavioral changes in clothing insulation related to actual environmental temperature. UTCI was developed conceptually as an equivalent temperature. Thus, for any combination of air temperature, wind, radiation, and humidity, UTCI is defined as the air temperature in the reference condition which would elicit the same dynamic response of the physiological model. This review analyses the sensitivity of UTCI to humidity and radiation in the heat and to wind in the cold and compares the results with observational studies and internationally standardized assessment procedures. The capabilities, restrictions and potential future extensions of UTCI are discussed.

  18. Draft environmental assessment: Ocean Thermal Energy Conversion (OTEC) Pilot Plants

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, S.M.; Sands, M.D.; Donat, J.R.; Jepsen, P.; Smookler, M.; Villa, J.F.

    1981-02-01

    This Environmental Assessment (EA) has been prepared, in accordance with the National Environmental Policy Act of 1969, for the deployment and operation of a commercial 40-Megawatt (MW) Ocean Thermal Energy Conversion (OTEC) Pilot Plant (hereafter called the Pilot Plant). A description of the proposed action is presented, and a generic environment typical of the candidate Pilot Plant siting regions is described. An assessment of the potential environmental impacts associated with the proposed action is given, and the risk of credible accidents and mitigating measures to reduce these risks are considered. The Federal and State plans and policies the proposed action will encompass are described. Alternatives to the proposed action are presented. Appendix A presents the navigation and environmental information contained in the US Coast Pilot for each of the candidate sites; Appendix B provides a brief description of the methods and calculations used in the EA. It is concluded that environmental disturbances associated with Pilot Plant activities could potentially cause significant environmental impacts; however, the magnitude of these potential impacts cannot presently be assessed, due to insufficient engineering and environmental information. A site- and design-specific OTEC Pilot Plant Environmental Impact Statement (EIS) is required to resolve the potentially significant environmental effects associated with Pilot Plant deployment and operation. (WHK)

  19. A Randomized, Controlled Trial to Assess the Effect of Topical Insulin Versus Normal Saline in Pressure Ulcer Healing.

    Science.gov (United States)

    Stephen, Shine; Agnihotri, Meenakshi; Kaur, Sukhpal

    2016-06-01

    Insulin has been used in wound healing to increase wound collagen, granulation tissue, wound tensile strength, and local production of insulin-like growth factors by fibroblasts. Saline is a widely used irrigating and wound dressing solution. Patients admitted to an acute care facility who had a Grade 2 or Grade 3 pressure ulcer were recruited to participate in a randomized, controlled trial to compare the effect of normal saline-impregnated gauze and insulin dressing in pressure ulcer healing. Persons with immunodeficiency, diabetes mellitus, pregnancy, osteomyelitis, and peripheral vascular illness were not eligible for the study. Study participants were randomized to receive either normal saline dressing gauze or insulin dressing twice daily for 7 days. At baseline, patient demographic data and ulcer history were recorded. Baseline and follow-up ulcer assessments (days 4 and day 7) included ulcer measurement (length and width) and completion of the Pressure Ulcer Scale for Healing (PUSH version 3.0) tool. Patients in the control group received dressings of sterile gauze soaked with normal saline; patients in the intervention group received topical insulin (1 U/cm2 wound area). The insulin was sprayed over the wound surface with an insulin syringe, allowed to dry for 15 minutes, and then covered with sterile gauze. To ascertain the safety of study participants, blood glucose levels were measured with a glucometer 10 minutes before and 1 hour after the topical insulin application in the intervention group. Treatment efficacy was deter- mined by assessing the reduction in wound area and PUSH scores at follow-up. Statistical analysis was performed; data are expressed as mean ± SD and percentage for continuous and categorical variables respectively. The differences in PUSH score and ulcer sizes between the 2 groups were analyzed using independent t-test, and within-group differences were analyzed using ANOVA with repeated measures; Greenhouse-Geisser correction was

  20. Assessment of research needs for advanced heterogeneous catalysts for energy applications. Final report: Volume 2, Topic reports

    Energy Technology Data Exchange (ETDEWEB)

    Mills, G.A.

    1994-04-01

    This report assesses the direction, technical content, and priority of research needs judged to provide the best chance of yielding new and improved heterogeneous catalysts for energy-related applications over the period of 5-20 years. It addresses issues of energy conservation, alternate fuels and feedstocks, and the economics and applications that could alleviate pollution from energy processes. Recommended goals are defined in 3 research thrusts: catalytic science, environmental protection by catalysis, and industrial catalytic applications. This study was conducted by an 11-member panel of experts from industry and academia, including one each from Japan and Europe. This volume first presents an in-depth overview of the role of catalysis in future energy technology in chapter 1; then current catalytic research is critically reviewed and research recommended in 8 topic chapters: catalyst preparation (design and synthesis), catalyst characterization (structure/function), catalyst performance testing, reaction kinetics/reactor design, catalysis for industrial chemicals, catalysis for electrical applications (clean fuels, pollution remediation), catalysis for control of exhaust emissions, and catalysts for liquid transportation fuels from petroleum, coal, residual oil, and biomass.

  1. Driver performance-based assessment of thermal display degradation effects

    Science.gov (United States)

    Ruffner, John W.; Massimi, Michael S.; Choi, Yoon S.; Ferrett, Donald A.

    1998-07-01

    The Driver's Vision Enhancer (DVE) is a thermal sensor and display combination currently being procured for use in U.S. Army combat and tactical wheeled vehicles. During the DVE production process, a given number of sensor or display pixels may either vary from the desired luminance values (nonuniform) or be inactive (nonresponsive). The amount and distribution of pixel luminance nonuniformity (NU) and nonresponsivity (NR) allowable in production DVEs is a significant cost factor. No driver performance-based criteria exist for determining the maximum amount of allowable NU and NR. For safety reasons, these characteristics are specified conservatively. This paper describes an experiment to assess the effects of different levels of display NU and NR on Army drivers' ability to identify scene features and obstacles using a simulated DVE display and videotaped driving scenarios. Baseline, NU, and NR display conditions were simulated using real-time image processing techniques and a computer graphics workstation. The results indicate that there is a small, but statistically insignificant decrease in identification performance with the NU conditions tested. The pattern of the performance-based results is consistent with drivers' subjective assessments of display adequacy. The implications of the results for specifying NU and NR criteria for the DVE display are discussed.

  2. Clindamycin Topical

    Science.gov (United States)

    ... topical clindamycin.you should know that abrasive or medicated soaps and skin products that contain alcohol may ... in, tightly closed, and out of reach of children. Store it at room temperature and away from ...

  3. Tretinoin Topical

    Science.gov (United States)

    ... lotions, astringents, and perfumes); they can sting your skin, especially when you first use tretinoin.Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or ...

  4. IEA implementing agreement for hybrid and electric vehicle technologies and programmes, Annex VII hybrid vehicles : Topic 13, assessment of the energy consumption of hybrid trucks using ADVISOR

    NARCIS (Netherlands)

    Eelkema, J.; Winkel, R.G.; Geraets, R.; Verbakel, M.J.L.

    2002-01-01

    This topic report focuses on the possible benefits of the application of a hybrid powertrain in heavy-duty vehicles. The main objective is to assess whether a significant reduction in fuel consumption is feasible. An average Dutch distribution truck with a conventional driveline will be compared to

  5. Finding self-directed learning readiness and fostering self-directed learning through weekly assessment of self-directed learning topics during undergraduate clinical training in ophthalmology

    Science.gov (United States)

    Sahoo, Soumendra

    2016-01-01

    Background: To know the individual’s current level of readiness and to manage self-directed learning (SDL) not only help learners but also the instructors. The objectives of this study were to find SDL readiness among 4th year medical student and to analyze the effect of weekly assessment of SDL topics. Methodology: This was a cross-sectional study to analyze the effect of weekly assessment of SDL topics in fostering SDL. The 51 4th year students during a clinical posting in ophthalmology participated for this study. Each recruited student was tested for SDL readiness through the SDL readiness scale (SDLRS) developed by Lucy Guglielmino (1978), which was validated in our local setting and responses were collected from students on the 1st day of the clinical posting. The students chose SDL topics which were assessed on a weekly basis in the form of scenario-based multiple choice questionnaires. Written feedback was collected from each student regarding such activity during their clinical posting, especially to know the actual utilization of SDL hours provided in teaching schedule, satisfaction on the type of questions and motivation for SDL. Results: The mean SDLRS score in male students were 214.15 ± 19.73 and in female 207.95 ± 17.983, which falls under average score as defined in Guglielmino scale. The majority of study population expressed better utilization of SDL study hours because of weekly assessment than when they had no assessment for SDL. Conclusions: Majority of the study population were found to be ready for SDL. The weekly assessment of SDL topics was found to stimulate proper utilization of SDL slots in teaching schedule thereby fostering SDL habits. PMID:27563580

  6. Assessment of the thermal environment in an aircraft cabin

    DEFF Research Database (Denmark)

    Ingers, S.; Melikov, Arsen Krikor

    2004-01-01

    A full-scale section of a flight cabin with 21 seats was used to study the thermal environment in aircraft under laboratory conditions. Fourteen heated cylinders and two thermal manikins were used to simulate the heat load, the buoyancy flow and the flow obstruction from passengers in the cabin. ...

  7. Assessment of the thermal environment in a simulated aircraft cabin using thermal manikin exposure

    DEFF Research Database (Denmark)

    Strøm-Tejsen, Peter; Zukowska, Daria; Jama, Agnieszka;

    2007-01-01

    The thermal environment in a full-scale 21-seat section of an aircraft cabin installed in a climate chamber was investigated. Fourteen heated cylinders and two thermal manikins were used to simulate the heat load, buoyancy flow and flow obstruction from passengers in the cabin. Measurements were...

  8. Assessing population and environmental effects on thermal resistance in Drosophila melanogaster using ecologically relevant assays

    DEFF Research Database (Denmark)

    Overgaard, Johannes; Hoffmann, Ary A; Kristensen, Torsten Nygård

    2011-01-01

    To make laboratory studies of thermal resistance in ectotherms more ecologically relevant, temperature changes that reflect conditions experienced by individuals in nature should be used. Here we describe an assay that is useful for quantifying multiple measures of thermal resistance of individual...... that the method could be routinely used in evaluating thermal responses potentially linked to ecological processes and evolutionary adaptation....... adult flies. We use this approach to assess upper and lower thermal limits and functional thermal scope for Drosophila melanogaster and also show that the method can be used to (1) detect a previously described latitudinal cline for cold tolerance in D. melanogaster populations collected along the east...

  9. Preface to Special Topic: Marine Renewable Energy

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, F. T.; Iglesias, G.; Santos, P. R.; Deng, Zhiqun

    2015-12-30

    Marine renewable energy (MRE) is generates from waves, currents, tides, and thermal resources in the ocean. MRE has been identified as a potential commercial-scale source of renewable energy. This special topic presents a compilation of works selected from the 3rd IAHR Europe Congress, held in Porto, Portugal, in 2014. It covers different subjects relevant to MRE, including resource assessment, marine energy sector policies, energy source comparisons based on levelized cost, proof-of-concept and new-technology development for wave and tidal energy exploitation, and assessment of possible inference between wave energy converters (WEC).

  10. Topical anesthesia

    Directory of Open Access Journals (Sweden)

    Mritunjay Kumar

    2015-01-01

    Full Text Available Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects.

  11. Assessing the performance of a soy methyl ester -polystyrene topical treatment to extend the service life of concrete structures

    Science.gov (United States)

    Thomas, D'Shawn G.

    Experimental results show that soy methyl ester (SME), a derivative of soy bean oil, along with the incorporation of polystyrene (PS) is a non-toxic, biodegradable and renewable material that can be used effectively as a topical concrete surface treatment. While, concrete sealants and topical surface treatments can be used to extend to durability of concrete structures, it is difficult to predict the durability of concrete structures sealed with a sealant or topical surface treatment. This is due to a lack of necessary model inputs that can be used to address the durability of concrete structures treated with these materials. In general, this thesis expands upon previous research in exploring the use of SME-PS blends as a topical treatment used to enhance concrete durability and presents a sound theoretical framework for modeling the durability of concrete structures topically treated with SME-PS using Fick's 2nd Law of diffusion. Using experimental data generated in this study, fluid transport tests have been carried out to investigate how SME-PS changes fluid absorption and chloride ingress into concrete. The results show that the diffusion of chloride ions into concrete treated with SME-PS can be modeled by using a fractional amount (in this case 60% is recommended) of the value of Cs that is used for conventional concrete when Fick 2 nd Law is used. This is critically important from a design and cost prospective, since tests do not need to be conducted with SME-PS to determine the benefits of surface treatment.

  12. Thermal comfort

    DEFF Research Database (Denmark)

    d’Ambrosio Alfano, Francesca Romana; Olesen, Bjarne W.; Palella, Boris Igor;

    2014-01-01

    Thermal comfort is one of the most important aspects of the indoor environmental quality due to its effects on well-being, people's performance and building energy requirements. Its attainment is not an easy task requiring advanced design and operation of building and HVAC systems, taking...... into account all parameters involved. Even though thermal comfort fundamentals are consolidated topics for more than forty years, often designers seem to ignore or apply them in a wrong way. Design input values from standards are often considered as universal values rather than recommended values to be used...... under specific conditions. At operation level, only few variables are taken into account with unpredictable effects on the assessment of comfort indices. In this paper, the main criteria for the design and assessment of thermal comfort are discussed in order to help building and HVAC systems designers...

  13. Thermal stability assessment of anti-explosive ammonium nitrate

    Institute of Scientific and Technical Information of China (English)

    Lijin Shen; Xuguang Wang

    2005-01-01

    The explosivity experiment of anti-explosive ammonium nitrate (AEAN) shows that the explosive characteristic of AEAN is eliminated. The adiabatic decompositions of ammonium nitrate and AEAN were investigated with an accelerating rate calorimeter (ARC). The curves of thermal decomposition temperature and pressure versus time, self-heating rate and pressure versus temperature for two systems were obtained. The kinetic parameters such as apparent activation energy and pre-exponential factor were calculated.The safety of AEAN was analyzed. It was indicated that AEAN has a higher thermal stability than AN. At the same time, it can be shown that the elimination of its explosive characteristic is due to the improvement on the thermal stability of AEAN.

  14. An investigation on the assessed thermal sensation and human body exergy consumption rate

    DEFF Research Database (Denmark)

    Simone, Angela; Kolarik, Jakub; Iwamatsu, Toshiya

    2010-01-01

    -environment research has been explored in the present work. The relationship of subjectively assessed thermal sensation data, from earlier thermal comfort studies, to the calculated human-body exergy consumption has been analysed. The results show that the minimum human body exergy consumption rate was related...

  15. Sensitivity Analysis of Personal Exposure Assessment Using a Breathing Thermal Manikin

    DEFF Research Database (Denmark)

    Brohus, Henrik; Nielsen, Peter V.; Jensen, Mikael K.

    2009-01-01

    The present work deals with the investigation of uncertainties related to personal exposure assessment using a breathing thermal manikin subject to a partly uniform velocity field in a wind channel. Several parameters are investigated: velocity level, thermal manikin heat flux, Archimedes number...

  16. Adjustment of the thermal component of two tourism climatological assessment tools using thermal perception and preference surveys from Hungary

    Science.gov (United States)

    Kovács, Attila; Unger, János; Gál, Csilla V.; Kántor, Noémi

    2016-07-01

    This study introduces new methodological concepts for integrating seasonal subjective thermal assessment patterns of people into the thermal components of two tourism climatological evaluation tools: the Tourism Climatic Index (TCI) and the Climate-Tourism/Transfer-Information-Scheme (CTIS). In the case of the TCI, we replaced the air temperature and relative humidity as the basis of the initial rating system with the physiologically equivalent temperature (PET)—a complex human biometeorological index. This modification improves the TCI's potential to evaluate the thermal aspects of climate. The major accomplishments of this study are (a) the development of a new, PET-based rating system and its integration into the thermal sub-indices of the TCI and (b) the regionalization of the thermal components of CTIS to reflect both the thermal sensation and preference patterns of people. A 2-year-long (2011-2012) thermal comfort survey conducted in Szeged, Hungary, from spring to autumn was utilized to demonstrate the implementation of the introduced concepts. We found considerable differences between the thermal perception and preference patterns of Hungarians, with additional variations across the evaluated seasons. This paper describes the proposed methodology for the integration of the new seasonal, perception-based, and preference-based PET rating systems into the TCI, and presents the incorporation of new PET thresholds into the CTIS. In order to demonstrate the utility of the modified evaluation tools, we performed case study climate analyses for three Hungarian tourist destinations. The additional adjustments introduced during the course of those analyses include the reduction of TCI's temporal resolution to 10-day intervals and the exclusion of nocturnal and winter periods from the investigation.

  17. Infrared Thermography Assessment of Thermal Bridges in Building Envelope: Experimental Validation in a Test Room Setup

    Directory of Open Access Journals (Sweden)

    Francesco Bianchi

    2014-10-01

    Full Text Available Thermal infrared imaging is a valuable tool to perform non-destructive qualitative tests and to investigate buildings envelope thermal-energy behavior. The assessment of envelope thermal insulation, ventilation, air leakages, and HVAC performance can be implemented through the analysis of each thermogram corresponding to an object surface temperature. Thermography also allows the identification of thermal bridges in buildings’ envelope that, together with windows and doors, constitute one of the weakest component increasing thermal losses. A quantitative methodology was proposed in previous researches by the authors in order to evaluate the effect of such weak point on the energy balance of the whole building. In the present work, in-field experimental measurements were carried out with the purpose of evaluating the energy losses through the envelope of a test room experimental field. In-situ thermal transmittance of walls, ceiling and roof were continuously monitored and each element was characterized by its own thermal insulation capability. Infrared thermography and the proposed quantitative methodology were applied to assess the energy losses due to thermal bridges. The main results show that the procedure confirms to be a reliable tool to quantify the incidence of thermal bridges in the envelope thermal losses.

  18. On-Orbit Health Monitoring and Repair Assessment of Thermal Protection Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR project delivers On-orbit health MoNItoring and repair assessment of THERMal protection systems (OMNI_THERM). OMNI_THERM features impedance-based...

  19. Thermal Storage Systems Assessment for Energy Sustainability in Housing Units

    Directory of Open Access Journals (Sweden)

    Tania I. Lagunes Vega

    2016-04-01

    Full Text Available In order to achieve greater enhancements in energy sustainability for housing, the function and efficiency of two different passive cooling systems were studied: encapsulated water in recycled bottles of Polyethylene terephthalate (PET and polystyrene plates, in comparison with standard concrete slab systems, which are customarily used in housing. Experiments were placed over a tile surface, in which temperature changes were monitored for a period of 20 days from 08:00 to 20:00. The efficiency of passive thermal storage systems was endorsed through statistical analysis using the “SPSS” software. This resulted in a 17% energy saving, thus promoting energy sustainability in housing units, which reduces the use of electrical appliances required to stabilize conditions to achieve optimum thermal comfort for the human body inside a house, therefore, reducing electrical power consumption, CO2 emissions to the atmosphere and generating savings. Due to the complexity of a system with temperature changes, a fractal analysis was performed for each experimental system, using the “Benoit” software (V.1.3 with self-compatible tools of rescaled range (R/S and a wavelets method, showing that the thermal fluctuations on the tiles with the thermal storage system adapt to the rescaled range analysis and the regular tiles adapt to the wavelets method.

  20. Transportation: Topic Paper E.

    Science.gov (United States)

    National Council on the Handicapped, Washington, DC.

    As one of a series of topic papers assessing federal laws and programs affecting persons with disabilities, this paper reviews the issue of transportation services. In the area of urban mass transit, four relevant pieces of legislation and public transportation accessibility regulations are cited, and cost issues are explored. Paratransit systems,…

  1. Breathing thermal manikins for indoor environment assessment: important characteristics and requirements

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor

    2004-01-01

    Recently breathing thermal manikins have been developed and used for indoor environment measurement, evaluation and optimization as well as validation of Computational Fluid Dynamics (CFD) predictions of airflow around a human body. Advances in the assessment of occupants¿ thermal comfort...... and perceived air quality by means of breathing thermal manikins have been made as well. In order to perform accurate measurements and realistic evaluation and assessment, the design and characteristics of a manikin must comply with certain requirements. The most important of these, such as number, size...... and shape of body segments, control mode, breathing simulation, etc. are discussed and specified in this paper....

  2. Breathing thermal manikin for indoor environment assessment: Important characteristics and requirements

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor

    2003-01-01

    Recently breathing thermal manikins have been developed and used for indoor environment measurement, evaluation and optimization as well as validation of Computational Fluid Dynamics (CFD) predictions of airflow around a human body. Advances in the assessment of occupants¿ thermal comfort...... and perceived air quality by means of breathing thermal manikins have been made as well. In order to perform accurate measurements and realistic evaluation and assessment, the design and characteristics of a manikin must comply with certain requirements. The most important of these, such as number, size...... and shape of body segments, control mode, breathing simulation, etc. are discussed and specified in this paper....

  3. Crop water-stress assessment using an airborne thermal scanner

    Science.gov (United States)

    Millard, J. P.; Jackson, R. D.; Reginato, R. J.; Idso, S. B.; Goettelman, R. C.

    1978-01-01

    An airborne thermal scanner was used to measure the temperature of a wheat crop canopy in Phoenix, Arizona. The results indicate that canopy temperatures acquired about an hour and a half past solar noon were well correlated with presunrise plant water tension, a parameter directly related to plant growth and development. Pseudo-colored thermal images reading directly in stress degree days, a unit indicative of crop irrigation needs and yield potential, were produced. The aircraft data showed significant within-field canopy temperature variability, indicating the superiority of the synoptic view provided by aircraft over localized ground measurements. The standard deviation between airborne and ground-acquired canopy temperatures was 2 C or less.

  4. Assessment of thermal insulation materials and systems for building applications

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    The primary goal of the study was to provide a proper foundation for decision making by the federal government, industry, and consumer. The report may be used to identify areas where new test methods and standards are needed to establish new programs for improving thermal performance of buildings, and as a basis for setting new or improved standards after the recommended test programs have been completed.

  5. Lamb Wave Assessment of Fatigue and Thermal Damage in Composites

    Science.gov (United States)

    Seale, Michael D.; Smith, Barry T.; Prosser, W. H.

    2004-01-01

    Among the various techniques available, ultrasonic Lamb waves offer a convenient method of evaluating composite materials. Since the Lamb wave velocity depends on the elastic properties of a structure, an effective tool exists to monitor damage in composites by measuring the velocity of these waves. Lamb wave measurements can propagate over long distances and are sensitive to the desired in-plane elastic properties of the material. This paper describes two studies which monitor fatigue damage and two studies which monitor thermal damage in composites using Lamb waves. In the fatigue studies, the Lamb wave velocity is compared to modulus measurements obtained using strain gage measurements in the first experiment and the velocity is monitored along with the crack density in the second. In the thermal damage studies, one examines samples which were exposed to varying temperatures for a three minute duration and the second includes rapid thermal damage in composites by intense laser beams. In all studies, the Lamb wave velocity is demonstrated to be an excellent method to monitor damage in composites.

  6. Assessment of human thermal perception in the hot-humid climate of Dar es Salaam, Tanzania

    Science.gov (United States)

    Ndetto, Emmanuel L.; Matzarakis, Andreas

    2017-01-01

    Dar es Salaam, Tanzania, is a typical African city along the Indian Ocean coast, and therefore an important urban area to examine human thermal perception in the hot-humid tropical climate. Earlier research on human bioclimate at Dar es Salaam indicated that heat stress prevails during the hot season from October to March, peaking between December and February, particularly the early afternoons. In order to assess the human thermal perception and adaptation, two popular places, one at an urban park and another at a beach environment, were selected and questionnaire surveys were conducted in August-September 2013 and January 2014, concurrently with local micro-meteorological measurements at survey locations. The thermal conditions were quantified in terms of the thermal index of the physiologically equivalent temperature (PET) using the micro-scale climate model RayMan. The thermal comfort range of human thermal comfort and the local thermal adaptive capacity were determined in respect to the thermal index by binning thermal sensation votes. The thermal comfort range was found to be well above that in temperate climates at about 23-31 °C of PET. The study could significantly contribute to urban planning in Dar es Salaam and other coastal cities in the tropics.

  7. Assessment of human thermal perception in the hot-humid climate of Dar es Salaam, Tanzania

    Science.gov (United States)

    Ndetto, Emmanuel L.; Matzarakis, Andreas

    2016-06-01

    Dar es Salaam, Tanzania, is a typical African city along the Indian Ocean coast, and therefore an important urban area to examine human thermal perception in the hot-humid tropical climate. Earlier research on human bioclimate at Dar es Salaam indicated that heat stress prevails during the hot season from October to March, peaking between December and February, particularly the early afternoons. In order to assess the human thermal perception and adaptation, two popular places, one at an urban park and another at a beach environment, were selected and questionnaire surveys were conducted in August-September 2013 and January 2014, concurrently with local micro-meteorological measurements at survey locations. The thermal conditions were quantified in terms of the thermal index of the physiologically equivalent temperature (PET) using the micro-scale climate model RayMan. The thermal comfort range of human thermal comfort and the local thermal adaptive capacity were determined in respect to the thermal index by binning thermal sensation votes. The thermal comfort range was found to be well above that in temperate climates at about 23-31 °C of PET. The study could significantly contribute to urban planning in Dar es Salaam and other coastal cities in the tropics.

  8. Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm

    Directory of Open Access Journals (Sweden)

    Jones Maureen

    2010-07-01

    Full Text Available Abstract Background At present, there is no effective vaccine or other approved product for the prevention of sexually transmitted human immunodeficiency virus type 1 (HIV-1 infection. It has been reported that women in resource-poor communities use vaginally applied citrus juices as topical microbicides. These easily accessible food products have historically been applied to prevent pregnancy and sexually transmitted diseases. The aim of this study was to evaluate the efficacy and cytotoxicity of these substances using an established topical microbicide testing algorithm. Freshly squeezed lemon and lime juice and household vinegar were tested in their original state or in pH neutralized form for efficacy and cytotoxicity in the CCR5-tropic cell-free entry and cell-associated transmission assays, CXCR4-tropic entry and fusion assays, and in a human PBMC-based anti-HIV-1 assay. These products were also tested for their effect on viability of cervico-vaginal cell lines, human cervical explant tissues, and beneficial Lactobacillus species. Results Natural lime and lemon juice and household vinegar demonstrated anti-HIV-1 activity and cytotoxicity in transformed cell lines. Neutralization of the products reduced both anti-HIV-1 activity and cytotoxicity, resulting in a low therapeutic window for both acidic and neutralized formulations. For the natural juices and vinegar, the IC50 was ≤ 3.5 (0.8-3.5% and the TC50 ≤ 6.3 (1.0-6.3%. All three liquid products inhibited viability of beneficial Lactobacillus species associated with vaginal health. Comparison of three different toxicity endpoints in the cervical HeLa cell line revealed that all three products affected membrane integrity, cytosolic enzyme release, and dehydrogenase enzyme activity in living cells. The juices and vinegar also exerted strong cytotoxicity in cervico-vaginal cell lines, mainly due to their acidic pH. In human cervical explant tissues, treatment with 5% lemon or lime juice

  9. Assessment of Thermal Behavior and Development of Thermal Design Guidelines for Integrated Power Electronics Modules

    OpenAIRE

    Pang, Ying-Feng

    2005-01-01

    With the increase dependency on electricity to provide correct form of electricity for lightning, machines, and home and office appliances, the need for the introduction of high reliability power electronics in converting the raw form of electricity into efficient electricity for these applications is uprising. One of the most common failures in power electronics is temperature related failure such as overheating. To address the issue of overheating, thermal management becomes an important ...

  10. Assessment of Thermal Comfort: A Study at Closed and Ventilated Call Centre

    Directory of Open Access Journals (Sweden)

    A. R. Ismail

    2010-01-01

    Full Text Available Problem statement: The aims of study were to investigate the effects of environmental factors including the human physiology and thermal comfort during the cycle of process works in workplace. Approach: The selected production line was handling the restoration of trouble report. The environment examined was the relative humidity (%, wind speed (m sec-1, illuminance (lux and air temperature (°C of the surrounding workstation area. The environmental factors were measured using thermal comfort apparatus, which is capable to measure simultaneously those mentioned environmental factors. The time series data of fluctuating level of factors were plotted to identify the significant changes of factors. Then the thermal comfort of the workers was assessed by using ISO Standard 7730 and thermal sensation scale by using Predicted Mean Vote (PMV. Further Predicted Percentage Dissatisfied (PPD is used to estimate the thermal comfort satisfaction of the occupant. Finally the PMV were plotted to present the thermal comfort scenario of workers involved in related workstation. Results: The thermal comfort assessment of this workplace which is slightly warm following by thermal sensation and likely to be dissatisfied by the occupant. Conclusion: The result indicated that the activity level and clothing more influenced comfort to the occupants.

  11. Assessing the thermoelectric properties of single InSb nanowires: the role of thermal contact resistance

    Science.gov (United States)

    Yazji, S.; Swinkels, M. Y.; De Luca, M.; Hoffmann, E. A.; Ercolani, D.; Roddaro, S.; Abstreiter, G.; Sorba, L.; Bakkers, E. P. A. M.; Zardo, I.

    2016-06-01

    The peculiar shape and dimensions of nanowires (NWs) have opened the way to their exploitation in thermoelectric applications. In general, the parameters entering into the thermoelectric figure of merit are strongly interdependent, which makes it difficult to realize an optimal thermoelectric material. In NWs, instead, the power factor can be increased and the thermal conductivity reduced, thus boosting the thermoelectric efficiency compared to bulk materials. However, the assessment of all the thermoelectric properties of a NW is experimentally very challenging. Here, we focus on InSb NWs, which have proved to be promising thermoelectric materials. The figure of merit is accurately determined by using a novel method based on a combination of Raman spectroscopy and electrical measurements. Remarkably, this type of experiment provides a powerful approach allowing us to neglect the role played by thermal contact resistance. Furthermore, we compare the thermal conductivity determined by this novel method to the one determined on the same sample by the thermal bridge method. In this latter approach, the thermal contact resistance is a non-negligible parameter, especially in NWs with large diameters. We provide experimental evidence of the crucial role played by thermal contact resistance in the assessment of the thermal properties of nanostructures, using two different measurement methods of the thermal conductivity.

  12. Acoustic emission assessment of interface cracking in thermal barrier coatings

    Science.gov (United States)

    Yang, Li; Zhong, Zhi-Chun; Zhou, Yi-Chun; Zhu, Wang; Zhang, Zhi-Biao; Cai, Can-Ying; Lu, Chun-Sheng

    2016-04-01

    In this paper, acoustic emission (AE) and digital image correlation methods were applied to monitor interface cracking in thermal barrier coatings under compression. The interface failure process can be identified via its AE features, including buckling, delamination incubation and spallation. According to the Fourier transformation of AE signals, there are four different failure modes: surface vertical cracks, opening and sliding interface cracks, and substrate deformation. The characteristic frequency of AE signals from surface vertical cracks is 0.21 MHz, whilst that of the two types of interface cracks are 0.43 and 0.29 MHz, respectively. The energy released of the two types of interface cracks are 0.43 and 0.29 MHz, respectively. Based on the energy released from cracking and the AE signals, a relationship is established between the interface crack length and AE parameters, which is in good agreement with experimental results.

  13. Maturity assessment of harumanis mango using thermal camera sensor

    Science.gov (United States)

    Sa'ad, F. S. A.; Shakaff, A. Y. Md.; Zakaria, A.; Abdullah, A. H.; Ibrahim, M. F.

    2017-03-01

    The perceived quality of fruits, such as mangoes, is greatly dependent on many parameters such as ripeness, shape, size, and is influenced by other factors such as harvesting time. Unfortunately, a manual fruit grading has several drawbacks such as subjectivity, tediousness and inconsistency. By automating the procedure, as well as developing new classification technique, it may solve these problems. This paper presents the novel work on the using Infrared as a Tool in Quality Monitoring of Harumanis Mangoes. The histogram of infrared image was used to distinguish and classify the level of ripeness of the fruits based on the colour spectrum by week. The approach proposed thermal data was able to achieve 90.5% correct classification.

  14. Combining several thermal indices to generate a unique heat comfort assessment methodology

    Directory of Open Access Journals (Sweden)

    Wissam EL Hachem

    2015-11-01

    Full Text Available Purpose: The proposed methodology hopes to provide a systematic multi-disciplinary approach to assess the thermal environment while minimizing unneeded efforts. Design/methodology/approach: Different factors affect the perception of the human thermal experience: metabolic rate (biology, surrounding temperatures (heat balance and environmental factors and cognitive treatment (physiology.This paper proposes a combination of different multidisciplinary variables to generate a unique heat comfort assessment methodology. The variables at stake are physiological, biological, and environmental. Our own heat analysis is thoroughly presented and all relevant equations are described. Findings: Most companies are oblivious about potential dangers of heat stress accidents and thus about methods to monitor and prevent them. This methodology enables the company or the concerned individual to conduct a preliminary assessment with minimal wasted resources and time in unnecessary steps whilst providing a guideline for a detailed study with minimal error rates if needed. More so, thermal comfort is an integral part of sound ergonomics practices, which in turn are decisive for the success of any lean six sigma initiative. Research limitations/implications: This methodology requires several full implementations to finalize its design. Originality/value: Most used heat comfort models are inherently uncertain and tiresome to apply. An extensive literature review confirms the need for a uniform assessment methodology that combines the different thermal comfort models such as the Fanger comfort model (PMV, PPD and WGBT since high error rates coupled with tiresome calculations often hinder the thermal assessment process.

  15. Program definition and assessment overview. [for thermal energy storage project management

    Science.gov (United States)

    Gordon, L. H.

    1980-01-01

    The implementation of a program level assessment of thermal energy storage technology thrusts for the near and far term to assure overall coherent energy storage program is considered. The identification and definition of potential thermal energy storage applications, definition of technology requirements, and appropriate market sectors are discussed along with the necessary coordination, planning, and preparation associated with program reviews, workshops, multi-year plans and annual operating plans for the major laboratory tasks.

  16. Assessing energy efficiency of electric car bottom furnaces intended for thermal energization of minerals

    Science.gov (United States)

    Nizhegorodov, A. I.

    2017-01-01

    The paper deals with a new concept of electric furnaces for roasting and thermal energization of vermiculite and other minerals with vibrational transportation of a single-layer mass under constant thermal field. The paper presents performance calculation and comparative assessment of energy data for furnaces of different modifications: flame and electric furnaces with three units, furnaces with six units and ones with series-parallel connection of units, and furnaces of new concept.

  17. Performance assessment of low pressure nuclear thermal propulsion

    Science.gov (United States)

    Gerrish, Harrold P., Jr.; Doughty, Glen E.

    1993-01-01

    An increase in Isp for nuclear thermal propulsion systems is desirable for reducing the propellant requirements and cost of future applications, such as the Mars Transfer Vehicle. Several previous design studies have suggested that the Isp could be increased substantially with hydrogen dissociation/recombination. Hydrogen molecules (H2), at high temperatures and low pressures, will dissociate to monatomic hydrogen (H). The reverse process (i.e., formation of H2 from H) is exothermic. The exothermic energy in a nozzle increases the kinetic energy and therefore, increases the Isp. The low pressure nuclear thermal propulsion system (LPNTP) system is expected to maximize the hydrogen dissociation/recombination and Isp by operating at high chamber temperatures and low chamber pressures. The process involves hydrogen flow through a high temperature, low pressure fission reactor, and out a nozzle. The high temperature (approximately 3000 K) of the hydrogen in the reactor is limited by the temperature limits of the reactor material. The minimum chamber pressure is about 1 atm because lower pressures decrease the engines thrust to weight ratio below acceptable limits. This study assumes that hydrogen leaves the reactor and enters the nozzle at the 3000 K equilibrium dissociation level. Hydrogen dissociation in the reactor does not affect LPNTP performance like dissociation in traditional chemical propulsion systems, because energy from the reactor resupplies energy lost due to hydrogen dissociation. Recombination takes place in the nozzle due primarily to a drop in temperature as the Mach number increases. However, as the Mach number increases beyond the nozzle throat, the static pressure and density of the flow decreases and minimizes the recombination. The ideal LPNTP Isp at 3000 K and 10 psia is 1160 seconds due to the added energy from fast recombination rates. The actual Isp depends on the finite kinetic reaction rates which affect the amount of monatomic hydrogen

  18. Assessment of thermal efficiency of heat recovery coke making

    Science.gov (United States)

    Tiwari, H. P.; Saxena, V. K.; Haldar, S. K.; Sriramoju, S. K.

    2017-02-01

    The heat recovery stamp charge coke making process is quite complicated due to the evolved volatile matter during coking, is partially combusted in oven crown and sole flue in a controlled manner to provide heat for producing metallurgical coke. Therefore, the control and efficient utilization of heat in the oven crown, and sole flue is difficult, which directly affects the operational efficiency. Considering the complexity and importance of thermal efficiency, evolution of different gases, combustion of gasses in oven crown and sole flue, and heating process of coke oven has been studied. A nonlinear regression methodology was used to predict temperature profile of different depth of coal cake during the coking. It was observed that the predicted temperature profile is in good agreement with the actual temperature profile (R2 = 0.98) and is validated with the actual temperature profile of other ovens. A complete study is being done to calculate the material balance, heat balance, and heat losses. This gives an overall understanding of heat flow which affects the heat penetration into the coal cake. The study confirms that 60% heat was utilized during coking.

  19. Implications of environmental externalities assessments for solar thermal powerplants

    Science.gov (United States)

    Lee, A. D.; Baechler, M. C.

    1991-03-01

    Externalities are those impacts of one activity on other activities that are not priced in the marketplace. An externality is said to exist when two conditions hold: (1) the utility or operations of one economic agent, A, include nonmonetary variables whose values are chosen by another economic agent, B, without regard to the effects on A, and (2) B does not pay A compensation equal to the incremental costs inflicted on A. Electricity generation involves a wide range of potential and actual environmental impacts. Legislative, permitting, and regulatory requirements directly or indirectly control certain environmental impacts, implicitly causing them to become internalized in the cost of electricity generation. Electricity generation, however, often produces residual environmental impacts that meet the definition of an externality. Mechanisms have been developed by several states to include the costs associated with externalities in the cost-effectiveness analyses of new powerplants. This paper examines these costs for solar thermal plants and applies two states' scoring methodologies to estimate how including externalities would affect the levelized costs of power from a solar plant in the Pacific Northwest. It concludes that including externalities in the economics can reduce the difference between the levelized cost of a coal and solar plant by between 0.74 and 2.42 cents/kWh.

  20. Feasibility Assessment of Thermal Barriers for RSRM Nozzle Joint Locations

    Science.gov (United States)

    Steinetz, Bruce M.; Dunlap, Patrick H., Jr.

    1999-01-01

    Solid rockets, including the Space Shuttle solid rocket motor, are generally manufactured in large segments which are then shipped to their final destination where they are assembled. These large segments are sealed with a system of primary and secondary 0-rings to contain combustion gases inside the rocket which are at pressures of up to 900 psi and temperatures of up to 5500 F. The seals are protected from hot combustion gases by thick layers of phenolic insulation and by joint-filling compounds between these layers. Recently, though, routine inspections of nozzle-to-case joints in the Shuttle solid rocket motors during disassembly revealed erosion of the primary O-rings. Jets of hot gas leaked through gaps in the joint-filling compound between the layers of insulation and impinged on the O-rings. This is not supposed to take place, so NASA and Thiokol, the manufacturer of the rockets, initiated an investigation and found that design improvements could be made in this joint. One such improvement would involve using NASA Lewis braided thermal barriers as another level of protection for the O-ring seals against the hot combustion gases.

  1. Assessment of methods used to determine the safety of the topical insect repellent N,N-diethyl-m-toluamide (DEET).

    Science.gov (United States)

    Chen-Hussey, Vanessa; Behrens, Ron; Logan, James G

    2014-06-03

    N,N-diethyl-m-toluamide (DEET) has been registered for commercial use as an insect repellent for over five decades, and is used widely across the world. Concerns over the safety of DEET first emerged during the 1980s after reports of encephalopathy following DEET exposure, particularly in children. However, the role of DEET in either the illness or deaths was and remains purely speculative. In response to these cases a number of reviews and investigations of DEET safety were carried out. Here we examine the methods used and information available to determine the safety of DEET in humans. Animal testing, observational studies and intervention trials have found no evidence of severe adverse events associated with recommended DEET use. Minor adverse effects noted in animal trials were associated with very large doses and were not replicated between different test species. The safety surveillance from extensive humans use reveals no association with severe adverse events. This review compares the toxicity assessment using three different models to define the risk assessment and safety threshold for DEET use in humans and discusses the clinical consequences of the thresholds derived from the models.The theoretical risks associated with wearing an insect repellent should be weighed against the reduction or prevention of the risk of fatal or debilitating diseases including malaria, dengue, yellow fever and filariasis. With over 48 million European residents travelling to regions where vector borne diseases are a threat in 2009, restricting the concentration of DEET containing repellents to 15% or less, as modelled in the 2010 EU directive, is likely to result in extensive sub-therapeutic activity where repellents are infrequently applied. Future European travellers, as a consequence of inadequate personal protection, could potentially be at increased risk of vector borne diseases. Risk assessments of repellents should take these factors into account when setting safe

  2. Assessment of the Mutagenic Activity of Extracts of Brazilian Propolis in Topical Pharmaceutical Formulations on Mammalian Cells In Vitro and In Vivo

    Directory of Open Access Journals (Sweden)

    Juliana Marques Senedese

    2011-01-01

    Full Text Available Propolis possesses various biological activities such as antibacterial, antifungal, anti-inflammatory, anesthetic and antioxidant properties. A topically applied product based on Brazilian green propolis was developed for the treatment of burns. For such substance to be used more safely in future clinical applications, the present study evaluated the mutagenic potential of topical formulations supplemented with green propolis extract (1.2, 2.4 and 3.6% based on the analysis of chromosomal aberrations and of micronuclei. In the in vitro studies, 3-h pulse (G1 phase of the cell cycle and continuous (20 h treatments were performed. In the in vivo assessment, the animals were injured on the back and then submitted to acute (24 h, subacute (7 days and subchronic (30 days treatments consisting of daily dermal applications of gels containing different concentrations of propolis. Similar frequencies of chromosomal aberrations were observed for cultures submitted to 3-h pulse and continuous treatment with gels containing different propolis concentrations and cultures not submitted to any treatment. However, in the continuous treatment cultures treated with the 3.6% propolis gel presented significantly lower mitotic indices than the negative control. No statistically significant differences in the frequencies of micronuclei were observed between animals treated with gels containing different concentrations of propolis and the negative control for the three treatment times. Under the present conditions, topical formulations containing different concentrations of green propolis used for the treatment of burns showed no mutagenic effect in either test system, but 3.6% propolis gel was found to be cytotoxic in the in vitro test.

  3. Seasonal thermal energy storage

    Science.gov (United States)

    Allen, R. D.; Kannberg, L. D.; Raymond, J. R.

    1984-05-01

    Seasonal thermal energy storage (STES) using heat or cold available from surplus, waste, climatic, or cogeneration sources show great promise to reduce peak demand, reduce electric utility load problems, and contribute to establishing favorable economics for district heating and cooling systems. Heated and chilled water can be injected, stored, and recovered from aquifers. Geologic materials are good thermal insulators, and potentially suitable aquifers are distributed throughout the United States. Potential energy sources for use in an aquifer thermal energy storage system include solar heat, power plant cogeneration, winter chill, and industrial waste heat source. Topics covered include: (1) the U.S. Department of Energy seasonal thermal energy storage program; (2) aquifer thermal energy storage technology; (3) alternative STES technology; (4) foreign studies in seasonal thermal energy storage; and (5) economic assessment.

  4. Thermal Assessment of Low-Cost Rural Housing—A Case Study in the Ecuadorian Andes

    Directory of Open Access Journals (Sweden)

    Isabel Miño-Rodríguez

    2016-09-01

    Full Text Available The aim of this research is to assess the indoor thermal performance of rural dwellings in the Ecuadorian highlands through both experimental and numerical analysis. A three-step methodology was applied to conduct the research: (a field data collection, (b building thermal model development and calibration, and (c comparison analysis and assessment of traditional improvement strategies. Qualitative and quantitative data were collected from two representative rural dwellings under typical usage conditions. The first is a traditional construction, medium-exposed thermal mass dwelling (Case A. The second is a local common, uninsulated, lightweight construction (Case B. The thermal model was calibrated by comparing hourly temperature values of the observed and the predicted indoor air temperature. A high correlation level (R2 was achieved between the observed and predicted data; 0.89 in Case A and 0.94 in Case B. The results show that the roof, floor, and the airtightness are the critical building parameters affecting the indoor thermal environment. Likewise, the indoor air temperature is increased up to 4 °C through the implementation of traditional strategies. However, despite the rise in indoor air temperature, acceptable thermal comfort ranges were only reached for 25% of the total hours.

  5. Assessing thermal comfort in Ghadames, Libya: application of the adaptive model

    Energy Technology Data Exchange (ETDEWEB)

    Taki, A.H.; Ealiwa, M.A.; Seden, M.R. [De Montfort Univ., School of Architecture, Leicester (United Kingdom); Howarth, A.T. [Nottingham Univ., School of the Built Environment, Nottingham (United Kingdom)

    1999-07-01

    This survey measures human thermal comfort and assesses the validity of the adaptive thermal comfort model when applied to the climatic extreme (hot dry) condition of Ghadames. This paper reviews the results from two field surveys of thermal comfort within two types of buildings, old (free running) and new (climate control), in Ghadames oasis in Libya in the summer seasons of August 1997 and July 1998. Questionnaires were collected from 19 buildings representing 88 subjects: nine old buildings that employ a natural ventilation system with a courtyard and ten new buildings that employ an air conditioning system. The results from the present study show that the neutral temperatures in old and new buildings are 31.6degC and 29.4degC respectively. The adaptive model is shown to be valid, without modification, for predicting the thermal comfort of sedentary occupants in such environments. (Author)

  6. Assessment of the potential of solar thermal small power systems in small utilities

    Science.gov (United States)

    Steitz, P.; Mayo, L. G.; Perkins, S. P., Jr.

    1978-01-01

    The potential economic benefit of small solar thermal electric power systems to small municipal and rural electric utilities is assessed. Five different solar thermal small power system configurations were considered in three different solar thermal technologies. The configurations included: (1) 1 MW, 2 MW, and 10 MW parabolic dish concentrators with a 15 kW heat engine mounted at the focal point of each dish, these systems utilized advanced battery energy storage; (2) a 10 MW system with variable slat concentrators and central steam Rankine energy conversion, this system utilized sensible thermal energy storage; and (3) a 50 MW central receiver system consisting of a field of heliostats concentrating energy on a tower-mounted receiver and a central steam Rankine conversion system, this system also utilized sensible thermal storage. The results are summarized in terms of break-even capital costs. The break-even capital cost was defined as the solar thermal plant capital cost which would have to be achieved in order for the solar thermal plants to penetrate 10 percent of the reference small utility generation mix by the year 2000. The calculated break-even capital costs are presented.

  7. ECMOR 4. 4th European conference on the mathematics of oil recovery. Topic B: Heterogeneity description and assessment of uncertainty. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    The report with collected proceedings from a conference, deals with mathematics of oil recovery with the focus on heterogeneity description and assessment of uncertainty. Topics of proceedings are as follow: Reservoir engineering and uncertainty - how much we know about what we don't know; sampling from Bayesian models in reservoir characterization; improvement in the truncated Gaussian method - combining several Gaussian functions; Levy stochastic model for the variations in the properties in sedimentary rock; modelling sub-seismic fault patterns using a marked point process; marked point models with complex conditioning used for modelling of shales; integration of large- and small-scale data using Fourier transforms; ranking of production performance from detailed geological models; direct solution reservoir flow equations with uncertain parameters. Nine papers are prepared. 83 refs., 58 figs., 1 tab.

  8. Thermal-hydraulic assessment of concrete storage cubicle with horizontal 3013 canisters

    Energy Technology Data Exchange (ETDEWEB)

    HEARD, F.J.

    1999-04-08

    The FIDAP computer code was used to perform a series of analyses to assess the thermal-hydraulic performance characteristics of the concrete plutonium storage cubicles, as modified for the horizontal placement of 3013 canisters. Four separate models were developed ranging from a full height model of the storage cubicle to a very detailed standalone model of a horizontal 3013 canister.

  9. Assessment of thermal sensitivity of CT during heating of liver : an ex vivo study

    NARCIS (Netherlands)

    Pandeya, G. D.; Greuter, M. J. W.; Schmidt, B.; Flohr, T.; Oudkerk, M.

    2012-01-01

    Objectives: The purpose of this study was to assess the thermal sensitivity of CT during heating of ex-vivo animal liver. Methods: Pig liver was indirectly heated from 20 to 90 degrees C by passage of hot air through a plastic tube. The temperature in the heated liver was measured using calibrated t

  10. Life cycle assessment of thermal Waste-to-Energy technologies: Review and recommendations

    DEFF Research Database (Denmark)

    Astrup, Thomas Fruergaard; Tonini, Davide; Turconi, Roberto

    2015-01-01

    Life cycle assessment (LCA) has been used extensively within the recent decade to evaluate the environmental performance of thermal Waste-to-Energy (WtE) technologies: incineration, co-combustion, pyrolysis and gasification. A critical review was carried out involving 250 individual case-studies ...

  11. A model of scientific attitudes assessment by observation in physics learning based scientific approach: case study of dynamic fluid topic in high school

    Science.gov (United States)

    Yusliana Ekawati, Elvin

    2017-01-01

    This study aimed to produce a model of scientific attitude assessment in terms of the observations for physics learning based scientific approach (case study of dynamic fluid topic in high school). Development of instruments in this study adaptation of the Plomp model, the procedure includes the initial investigation, design, construction, testing, evaluation and revision. The test is done in Surakarta, so that the data obtained are analyzed using Aiken formula to determine the validity of the content of the instrument, Cronbach’s alpha to determine the reliability of the instrument, and construct validity using confirmatory factor analysis with LISREL 8.50 program. The results of this research were conceptual models, instruments and guidelines on scientific attitudes assessment by observation. The construct assessment instruments include components of curiosity, objectivity, suspended judgment, open-mindedness, honesty and perseverance. The construct validity of instruments has been qualified (rated load factor > 0.3). The reliability of the model is quite good with the Alpha value 0.899 (> 0.7). The test showed that the model fits the theoretical models are supported by empirical data, namely p-value 0.315 (≥ 0.05), RMSEA 0.027 (≤ 0.08)

  12. Analysis of heart rate control to assess thermal sensitivity responses in Brazilian toads

    Directory of Open Access Journals (Sweden)

    J.E.S. Natali

    2015-01-01

    Full Text Available In anurans, changes in ambient temperature influence body temperature and, therefore, energy consumption. These changes ultimately affect energy supply and, consequently, heart rate (HR. Typically, anurans living in different thermal environments have different thermal sensitivities, and these cannot be distinguished by changes in HR. We hypothesized that Rhinella jimi (a toad from a xeric environment that lives in a wide range of temperatures would have a lower thermal sensitivity regarding cardiac control than R. icterica (originally from a tropical forest environment with a more restricted range of ambient temperatures. Thermal sensitivity was assessed by comparing animals housed at 15° and 25°C. Cardiac control was estimated by heart rate variability (HRV and heart rate complexity (HRC. Differences in HRV between the two temperatures were not significant (P=0.214 for R. icterica and P=0.328 for R. jimi, whereas HRC differences were. All specimens but one R. jimi had a lower HRC at 15°C (all P<0.01. These results indicate that R. jimi has a lower thermal sensitivity and that cardiac control is not completely dependent on the thermal environment because HRC was not consistently different between temperatures in all R. jimi specimens. This result indicates a lack of evolutive trade-offs among temperatures given that heart rate control at 25°C is potentially not a constraint to heart rate control at 15°C.

  13. Analysis of heart rate control to assess thermal sensitivity responses in Brazilian toads.

    Science.gov (United States)

    Natali, J E S; Santos, B T; Rodrigues, V H; Chauí-Berlinck, J G

    2015-01-01

    In anurans, changes in ambient temperature influence body temperature and, therefore, energy consumption. These changes ultimately affect energy supply and, consequently, heart rate (HR). Typically, anurans living in different thermal environments have different thermal sensitivities, and these cannot be distinguished by changes in HR. We hypothesized that Rhinella jimi (a toad from a xeric environment that lives in a wide range of temperatures) would have a lower thermal sensitivity regarding cardiac control than R. icterica (originally from a tropical forest environment with a more restricted range of ambient temperatures). Thermal sensitivity was assessed by comparing animals housed at 15° and 25°C. Cardiac control was estimated by heart rate variability (HRV) and heart rate complexity (HRC). Differences in HRV between the two temperatures were not significant (P=0.214 for R. icterica and P=0.328 for R. jimi), whereas HRC differences were. All specimens but one R. jimi had a lower HRC at 15°C (all P<0.01). These results indicate that R. jimi has a lower thermal sensitivity and that cardiac control is not completely dependent on the thermal environment because HRC was not consistently different between temperatures in all R. jimi specimens. This result indicates a lack of evolutive trade-offs among temperatures given that heart rate control at 25°C is potentially not a constraint to heart rate control at 15°C.

  14. Condition Assessment on Thermal Effects of a Suspension Bridge Based on SHM Oriented Model and Data

    Directory of Open Access Journals (Sweden)

    Bo Chen

    2013-01-01

    Full Text Available This paper aims to carry out the condition assessment on temperature distribution and thermal effects of a long span suspension bridge. The structural health monitoring (SHM oriented data analysis is first performed and several indices are developed to process the time-varying temperature, displacement, and strain responses. An analytical procedure based on heat transfer theory is presented to determine the temperature distributions within the bridge. The fine finite element models of the deck plate, the cross frame, and the bridge tower are constructed for thermal analysis. A new approach to the thermal-structural coupling analysis of long span bridges is proposed to examine the structural thermal effects. The feasibility and validity of the proposed data process method and the new approach for thermal-structural coupling analysis are examined through detailed numerical simulation. The numerical results are compared with the field measurement data obtained from the long-term monitoring system of the bridge and they show a very good agreement, in terms of temperature distribution in different time and in different seasons. This exercise verifies the accuracy of the heat transfer analysis employed and the effectiveness and validity of the proposed approaches for data processing and thermal-structural coupling analysis.

  15. Thermal maturity assessment of the Upper Triassic to Lower Jurassic Nampo Group, mid-west Korea: Reconstruction of thermal history

    Energy Technology Data Exchange (ETDEWEB)

    Egawa, K.; Il Lee, Y. [Seoul National University, Seoul (Republic of Korea). School of Earth & Environmental Science

    2008-03-15

    Thermal maturity of the Upper Triassic to Lower Jurassic Nampo Group, a sediment-fill of the Chungnam Basin located in the central western part of South Korea, was assessed by illite crystallinity measurement and sandstone microtexture analysis. The Nampo Group consists of a fluvio-lacustrine deposit bearing meta-anthracitic coals and was over-thrusted by the basement rocks. Sandstones are characterized by down sequence increasing illite crystallinity, from anchizone to epizone, which is strongly suggestive of burial heating. Deep-burial diagenesis and deformation are evidenced by well-developed pressure solution textures, whose intensity tends to increase down sequence, and by ductile deformation in the lowermost strata. On the basis of the result of illite crystallinity measurement, the maximum paleo-temperature and total burial depth of the Nampo Group are estimated to be ca 340{sup o}C and 10 km, respectively; these conditions are in good agreement with the observed ductile deformation features. The absence of strata younger than the Nampo Group in and around the Chungnam Basin suggests that deep burial of the Nampo Group was caused by tectonic crustal loading. The tectonic overload was because of basement over-thrusting that occurred during the Jurassic Daebo orogeny, which is closely related to the orthogonal subduction of the Izanagi Plate beneath the East Asian continent. Subsequent hydrothermal alteration disturbed the thermal maturity pattern, resulting in anomalously high illite crystallinity and meta-anthracitization.

  16. Assessment of the potential of solar thermal small power systems in small utilities. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Steitz, P.; Mayo, L.G.; Perkins, S.P. Jr.

    1978-11-01

    This study involved an assessment of the potential economic benefit of small solar thermal electric power systems to small municipal and rural electric utilities. Five different solar thermal small power system configurations were considered in the study representing three different solar thermal technologies. The configurations included: (1) 1-MW, 2-MW, and 10-MW parabolic dish concentrators with a 15-kW heat engine mounted at the focal point of each dish. These systems utilized advanced battery energy storage. (2) A 10-MW system with variable slat concentrators and central steam Rankine energy conversion. This system utilized sensible thermal energy storage. (3) A 50-MW central receiver system consisting of a field of heliostats concentrating energy on a tower-mounted receiver and a central steam Rankine conversion system. This system also utilized sensible thermal storage. The approach used in determining the potential for solar thermal small power systems in the small utility market involved a comparison of the economics of power supply expansion plans for seven hypothetical small utilities through the year 2000 both with and without the solar thermal small power systems. Insolation typical of the Southwestern US was assumed. A comparison of the break-even capital costs with the range of plant costs estimated in this study yields the following conclusions: (1) The parabolic dish concentrator systems could be economically competitive with conventional generation if the lowest capital costs can be achieved. (2) The variable slat concentrator and central receiver systems would have to achieve lower costs than the lowest in the cost ranges generally assumed in the study to become economically competitive. (3) All of the solar thermal plant types are potentially more competitive in utilities which are heavily dependent upon oil.

  17. Topics in theoretical astrophysics: Precession of warped disks, oscillations of presupernova stars, and thermal evolution and nucleosynthesis of young neutron stars

    Science.gov (United States)

    Shirakawa, Akiko

    This thesis consists of three parts. In the first part, we study the magnetically driven precession of warped disks. An accretion disk around a rotating magnetized star is subjected to the magnetic torques that induce warping and precession of the disk. We study the global hydrodynamical warping/ precession modes of the disk under the combined influences of the magnetic torques, relativistic frame dragging, and the classical precession due to oblateness of the neutron star. We apply our analysis to two types of accreting systems: low-mass X-ray binaries (LMXBs) and accreting X-ray pulsars. We argue that some features of low-frequency quasi-periodic oscillations (QPOs) in LMXBs and milli-Hertz QPOs in accreting X-ray pulsars can be explained by the magnetically driven precession of warped disks. The second part is related to the hydrodynamically-driven mechanism for asymmetric supernova explosions/neutron star kicks. We explore the possibility that the gravity modes in the core of a presupernova star may be amplified in the silicon burning shell to produce the global asymmetric perturbations that lead to an asymmetric supernova explosion. By performing a linear analysis of the oscillations in the cores of presupernova stars, we estimate the growth/ damping rates of the modes. We find that most of the modes are damping modes with a few exceptions. We also find that, even for a growing mode, the timescale of mode growth is much longer than the remaining time before the core collapse. We conclude that the gravity modes in a presupernova core cannot provide the global asymmetric perturbations that lead to an asymmetric supernova explosion. In the last part, we attempt to predict the innate chemical composition of a neutron star atmosphere. There has been great progress in X-ray observations and now thermal radiation from neutron stars is being studied in detail. There has also been significant progress in modeling thermal spectra from neutron stars. However, the unknown

  18. Assessing Consistency in Radiated Thermal Output of Beef Steers by Infrared Thermography

    Directory of Open Access Journals (Sweden)

    Nigel Cook

    2016-07-01

    Full Text Available Measurements of radiated thermal output are claimed to reflect the metabolic efficiency of mammals. This is important in food-producing animals because a measure of metabolic efficiency may translate to desirable characteristics, such as growth efficiency or residual feed intake, and permit the grouping of animals by metabolic characteristics that can be more precisely managed. This study addresses the question of whether radiated thermal parameters are characteristic of individual animals under normal and metabolically-challenging conditions. Consistency in radiated thermal output was demonstrated over a period of four weeks on condition that a sufficiently representative sample of measurements could be made on individual animals. The study provided evidence that infrared thermography could be used as an automated, rapid, and reliable tool for assessing thermoregulatory processes.

  19. Qualitative Screening Method for Impact Assessment of Uncertain Building Geometry on Thermal Energy Demand Predictions

    Science.gov (United States)

    Wate, P.; Coors, V.; Robinson, D.; Iglesias, M.

    2016-10-01

    Virtual 3D models of cities are now being extensively employed for the estimation of thermal energy demand at varying spatial and temporal scales. Efforts in preparing and management of the datasets required for the simulations have reached an advanced stage. Thus allowing to perform city scale simulations using simplified thermal energy balance models. However, the uncertainty inherent in datasets and the reliability of their data sources are often not given due consideration. Such consideration to the uncertainty problem would need a paradigm shift in simulation practices from a single value assignment to uncertainty characterization followed by assessment of qualitative and quantitative impact on the simulation results. The proposed study establishes a mechanism to handle the uncertainty arising from the building geometry reconstruction process and its possible consequences on the thermal energy demand calculations.

  20. A relation between calculated human body exergy consumption rate and subjectively assessed thermal sensation

    DEFF Research Database (Denmark)

    Simone, Angela; Kolarik, Jakub; Iwamatsu, Toshiya

    2011-01-01

    . Generally, the relationship between air temperature and the exergy consumption rate, as a first approximation, shows an increasing trend. Taking account of both convective and radiative heat exchange between the human body and the surrounding environment by using the calculated operative temperature, exergy...... consumption rates increase as the operative temperature increases above 24 ◦C or decreases below 22 ◦C. With the data available so far, a second-order polynomial relationship between thermal sensation and the exergy consumption rate was established....... occupants, it is reasonable to consider both the exergy flows in building and those within the human body. Until now, no data have been available on the relation between human-body exergy consumption rates and subjectively assessed thermal sensation. The objective of the present work was to relate thermal...

  1. Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging

    Science.gov (United States)

    Lee, Robert C.; Darling, Cynthia L.; Fried, Daniel

    2016-02-01

    Accurate detection and measurement of the highly mineralized surface layer that forms on caries lesions is important for the diagnosis of lesion activity. Previous studies have demonstrated that optical imaging methods can be used to measure the degree of remineralization on enamel lesions. The purpose of this study was to determine if thermal and near-IR reflectance imaging could be used to assess the remineralization process in simulated dentin lesions. Artificial bovine (n=15) dentin lesions were prepared by immersion in a demineralization solution for 24 hours and they were subsequently placed in an acidic remineralization solution for up to 12 days. The samples were dehydrated using an air spray for 30 seconds and imaged using thermal and InGaAs cameras. The area enclosed by the time-temperature curve, ΔQ, from thermal imaging decreased significantly with longer periods of remineralization. However, near-IR reflectance intensity differences, ΔI, before and after dehydration failed to show any significant relationship with the degree of remineralization. This study shows that thermal imaging can be used for the assessment of the remineralization of dentin lesions.

  2. Health Risk Assessment of Inhalable Particulate Matter in Beijing Based on the Thermal Environment

    Directory of Open Access Journals (Sweden)

    Lin-Yu Xu

    2014-11-01

    Full Text Available Inhalable particulate matter (PM10 is a primary air pollutant closely related to public health, and an especially serious problem in urban areas. The urban heat island (UHI effect has made the urban PM10 pollution situation more complex and severe. In this study, we established a health risk assessment system utilizing an epidemiological method taking the thermal environment effects into consideration. We utilized a remote sensing method to retrieve the PM10 concentration, UHI, Normalized Difference Vegetation Index (NDVI, and Normalized Difference Water Index (NDWI. With the correlation between difference vegetation index (DVI and PM10 concentration, we utilized the established model between PM10 and thermal environmental indicators to evaluate the PM10 health risks based on the epidemiological study. Additionally, with the regulation of UHI, NDVI and NDWI, we aimed at regulating the PM10 health risks and thermal environment simultaneously. This study attempted to accomplish concurrent thermal environment regulation and elimination of PM10 health risks through control of UHI intensity. The results indicate that urban Beijing has a higher PM10 health risk than rural areas; PM10 health risk based on the thermal environment is 1.145, which is similar to the health risk calculated (1.144 from the PM10 concentration inversion; according to the regulation results, regulation of UHI and NDVI is effective and helpful for mitigation of PM10 health risk in functional zones.

  3. Feasibility Assessment of Thermal Management System for Green Power Sources Using Nanofluid

    Directory of Open Access Journals (Sweden)

    Yi-Hsuan Hung

    2013-01-01

    Full Text Available A thermal management system using alumina (Al2O3/water as the nanofluid for green power sources was experimentally assessed in this paper. Basic thermal principles and formulas were utilized to evaluate the performance of an air-cooled heat exchanger. The Al2O3/water nanofluid was produced at the concentrations of 0.5, 1.0, and 1.5 wt.%. The testing conditions of this experiments were above three concentrations, five coolant flow rates (0.8, 1.2, 1.6, 2.0, and 2.4 L/min., and three heating powers (50, 100, and 150 W. Firstly, basic properties of nanoparticles were analyzed. Fundamental relationships of the Al2O3/water nanofluid with respect to temperatures and concentrations were measured such as: viscosity, density, and specific heat. Next, an innovative concept named efficiency factor (EF was proposed to quantitatively evaluate the thermal system performance. The enhancement of thermal system performance compared with distilled water was then defined as an efficiency factor ratio (REF. The experimental results demonstrated that the efficiency factor ratios were optimal at low flow rate (0.8 L/min. and low concentration (0.5%. Values of REF were all below 1.0 at high flow rates (1.2–2.4 L/min.. This research points out the direction of optimizing a thermal management system for green energy sources in the near future.

  4. Assessment of thermal structure of boundary layer atmosphere of Western Siberia

    OpenAIRE

    Akhmetshina, Anna

    2013-01-01

    The assessment of frequency of temperature inversions makes it possible to investigate the probability of coincidence of unfavorable conditions of atmospheric stratification and the results of the intensive business activity. This paper is devoted to the study of thermal structure of the atmosphere boundary layer of Western Siberian territory in the period from 1990 to 2010 by using reanalysis of NCEP/NCAR data. The data of reanalysis is the only available information for similar research. Ba...

  5. Thermochemical cycles for energy storage: Thermal decomposition of ZnCO{sub 4} systems. Final topical report, January 1, 1982--December 31, 1984

    Energy Technology Data Exchange (ETDEWEB)

    Wentworth, W.E. [Houston Univ., TX (United States)

    1992-04-01

    The overall objective of our research has been to develop thermochemical cycles that can be used for energy storage. A specific cycle involving ammonium hydrogen sulfate (NH{sub 4}HSO{sub 4}) has been proposed. Each reaction in the proposed cycle has been examined experimentally. Emphasis has been placed on the basic chemistry of these reactions. In the concluding phase of this research, reported herein, we have shown that when NH{sub 4}HSO{sub 4} is mixed with ZnO and decomposed, the resulting products can be released stepwise (H{sub 2}A{sub (g)} at {approximately}163{degrees}C, NH{sub 3(g)} at 365--418{degrees}C, and a mixture of SO{sub 2(g)} and SO{sub 3(g)} at {approximately}900{degrees}C) and separated by controlling the reaction temperature. Side reactions do not appear to be significant and the respective yields are high as would be required for the successful use of this energy storage reaction in the proposed cycle. Thermodynamic, kinetic, and other reaction parameters have been measured for the various steps of the reaction. Finally we have completed a detailed investigation of one particular reaction: the thermal decomposition of zinc sulfate (ZnSO{sub 4}). We have demonstrated that this reaction can be accelerated and the temperature required reduced by the addition of excess ZnO, V{sub 2}A{sub 5} and possibly other metal oxides.

  6. Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes.

    Science.gov (United States)

    Hellman, Lance M; Yin, Liusong; Wang, Yuan; Blevins, Sydney J; Riley, Timothy P; Belden, Orrin S; Spear, Timothy T; Nishimura, Michael I; Stern, Lawrence J; Baker, Brian M

    2016-05-01

    Measurements of thermal stability by circular dichroism (CD) spectroscopy have been widely used to assess the binding of peptides to MHC proteins, particularly within the structural immunology community. Although thermal stability assays offer advantages over other approaches such as IC50 measurements, CD-based stability measurements are hindered by large sample requirements and low throughput. Here we demonstrate that an alternative approach based on differential scanning fluorimetry (DSF) yields results comparable to those based on CD for both class I and class II complexes. As they require much less sample, DSF-based measurements reduce demands on protein production strategies and are amenable for high throughput studies. DSF can thus not only replace CD as a means to assess peptide/MHC thermal stability, but can complement other peptide-MHC binding assays used in screening, epitope discovery, and vaccine design. Due to the physical process probed, DSF can also uncover complexities not observed with other techniques. Lastly, we show that DSF can also be used to assess peptide/MHC kinetic stability, allowing for a single experimental setup to probe both binding equilibria and kinetics.

  7. Objective assessment of topical anti-inflammatory drug activity on experimentally induced nickel contact dermatitis: comparison between visual scoring, colorimetry, laser Doppler velocimetry and transepidermal water loss.

    Science.gov (United States)

    Queille-Roussel, C; Duteil, L; Padilla, J M; Poncet, M; Czernielewski, J

    1990-01-01

    Four topical anti-inflammatory drugs were investigated for their effect on allergic contact dermatitis. Nickel dermatitis was chosen for its high incidence in European healthy volunteers. Experimental lesions were treated twice daily with two steroids, two non-steroidal anti-inflammatory drugs and a blank base for 4.5 days without occlusion. The influence of treatments was assessed by daily visual grading and one site was left untreated for comparison over the same period. To quantify drug activities objectively, skin colour (colorimetry), skin blood flow (laser Doppler velocimetry) and transepidermal water loss (evaporimetry) were measured before drugs were first applied, then 6 hr after the last application. As expected, only Dermoval cream significantly improved the spontaneous clinical evolution in comparison with the other creams (Hydrocortisone Aster à 1%. Parfenac, indomethacin 2.5% and Skinbase) and the untreated site. Colorimetric parameter a* (redness) and L* (luminance) showed more differences between treatments than the other criteria and a close relationship was obtained between these two parameters and skin blood flow, all three being highly correlated to visual grading. Transepidermal water loss appeared less related to clinical improvement but this parameter could prove helpful for detecting compounds which could be irritant to diseased skin.

  8. Topical report review status

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review schedules, of all topical reports currently accepted for review by the NRC. This report will be published annually. Each sponsoring organization with one or more topical reports accepted for review copies.

  9. Analytical Methodology Used To Assess/Refine Observatory Thermal Vacuum Test Conditions For the Landsat 8 Data Continuity Mission

    Science.gov (United States)

    Fantano, Louis

    2015-01-01

    Thermal and Fluids Analysis Workshop Silver Spring, MD NCTS 21070-15 The Landsat 8 Data Continuity Mission, which is part of the United States Geologic Survey (USGS), launched February 11, 2013. A Landsat environmental test requirement mandated that test conditions bound worst-case flight thermal environments. This paper describes a rigorous analytical methodology applied to assess refine proposed thermal vacuum test conditions and the issues encountered attempting to satisfy this requirement.

  10. Assessment of Accrued Damage and Remaining Useful Life in Leadfree Electronics Subjected to Multiple Thermal Environments of Thermal Aging and Thermal Cycling

    Data.gov (United States)

    National Aeronautics and Space Administration — A method has been developed for prognostication of accrued prior damage in electronics subjected to overlapping sequential environments of thermal aging and thermal...

  11. Assessment of the Impact of the Measurement Precision of Thermal Properties of Materials on the Prediction of Their Thermal Behaviour

    Science.gov (United States)

    Khatun, Ayesha

    The thermal properties of the sidewall lining materials are capturing attention since the last two decades. Good prediction of the dynamic thermal behaviour of Hall Heroult cells, including precise estimation of energy losses and location of the side ledge formed by the solidification of electrolytic bath, is made possible when the sidelining materials are well characterized in function of temperature. The present work aim at measuring the thermal diffusivity, heat capacity and thermal conductivity of silicon carbide (SiC), graphitic and graphitized carbon materials and cryolite (Na3AlF 6) based on transient characterization techniques. The thermal diffusivity and the heat capacity are measured by using state-of-the-art transient laser flash analyzer and differential scanning calorimeter respectively. The thermal conductivity is calculated by assuming a constant density. The range of precision error for each thermal property is also calculated for a finite number of data sets. Empirical correlation has been drawn for each of the properties to describe the relation with temperature in mathematical terms. Thermal characterization of the latent heat evolved during the melting of ledge is also carried out. Finally, based on the calculations conducted with a 2-D numerical model, the effect of the precision errors of temperature varying thermal properties of the sidewall materials and ledge on the dynamic behaviour of a laboratory scale phase change reactor is also presented. The results, so obtained, encourage further studies on the thermal properties of materials used in the aluminium reduction cell to find out the thermal environment inside the cell, heat loss estimation and effect of the additives on the location of ledge. Key words: Thermal conductivity, thermal diffusivity, heat capacity, temperature varying properties, precision error, phase change profile, latent heat.

  12. The physiological equivalent temperature - a universal index for the biometeorological assessment of the thermal environment.

    Science.gov (United States)

    Höppe, P

    1999-10-01

    With considerably increased coverage of weather information in the news media in recent years in many countries, there is also more demand for data that are applicable and useful for everyday life. Both the perception of the thermal component of weather as well as the appropriate clothing for thermal comfort result from the integral effects of all meteorological parameters relevant for heat exchange between the body and its environment. Regulatory physiological processes can affect the relative importance of meteorological parameters, e.g. wind velocity becomes more important when the body is sweating. In order to take into account all these factors, it is necessary to use a heat-balance model of the human body. The physiological equivalent temperature (PET) is based on the Munich Energy-balance Model for Individuals (MEMI), which models the thermal conditions of the human body in a physiologically relevant way. PET is defined as the air temperature at which, in a typical indoor setting (without wind and solar radiation), the heat budget of the human body is balanced with the same core and skin temperature as under the complex outdoor conditions to be assessed. This way PET enables a layperson to compare the integral effects of complex thermal conditions outside with his or her own experience indoors. On hot summer days, for example, with direct solar irradiation the PET value may be more than 20 K higher than the air temperature, on a windy day in winter up to 15 K lower.

  13. Assessment of the Use of Nanofluids in Spacecraft Active Thermal Control Systems

    Science.gov (United States)

    Ungar, Eugene K.; Erickson, Lisa R.

    2011-01-01

    The addition of metallic nanoparticles to a base heat transfer fluid can dramatically increase its thermal conductivity. These nanofluids have been shown to have advantages in some heat transport systems. Their enhanced properties can allow lower system volumetric flow rates and can reduce the required pumping power. Nanofluids have been suggested for use as working fluids for spacecraft Active Thermal Control Systems (ATCSs). However, there are no studies showing the end-to-end effect of nanofluids on the design and performance of spacecraft ATCSs. In the present work, a parametric study is performed to assess the use of nanofluids in a spacecraft ATCSs. The design parameters of the current Orion capsule and the tabulated thermophysical properties of nanofluids are used to assess the possible benefits of nanofluids and how their incorporation affects the overall design of a spacecraft ATCS. The study shows that the unique system and component-level design parameters of spacecraft ATCSs render them best suited for pure working fluids. The addition of nanoparticles to typical spacecraft thermal control working fluids actually results in an increase in the system mass and required pumping power.

  14. Comparative study of approaches to assess damage in thermally fatigued Cusbnd Crsbnd Zr alloy

    Science.gov (United States)

    Chatterjee, Arya; Mitra, R.; Chakraborty, A. K.; Rotti, C.; Ray, K. K.

    2016-06-01

    For the first time the nature of response of thermal fatigue damage (TFD) in Cusbnd Crsbnd Zr alloys, considered for the High Heat Flux components of Tokamak and its subsystems in International Thermonuclear Experimental Reactor application has been studied. Temperature cycling between 290 °C and 30 °C, similar to the service condition, has been carried out on two differently aged Cusbnd Crsbnd Zr alloys. The TFD has been assessed by damage mechanics approach using damage parameters, and by surface characteristics. The damage parameters increase exponentially during initial fatigue cycles and saturates, whilst surface characteristics shows continuous increase with increase in thermal fatigue cycles. Damages are different in the aged alloys depending upon the aging conditions.

  15. A novel ex vivo skin model for the assessment of the potential transcutaneous anti-inflammatory effect of topically applied Harpagophytum procumbens extract.

    Science.gov (United States)

    Ouitas, Nassima Abdelouahab; Heard, Charles M

    2009-07-06

    Using ex vivo skin as a model, this work tested the hypothesis that the major pharmacologically active components of topically applied Harpagophytum procumbens (H. procumbens) can elicit anti-inflammatory responses in deeper tissues post-transcutaneous delivery. Using Franz-type diffusion cells, ethanol extract of powdered H. procumbens tuber was dosed onto freshly excised porcine skin. After 24 h the receptor phase was recovered, analysed for the major glycosides of DC, then used directly to dose further freshly excised skin membranes. After 6h the skin was recovered and probed for the expression of the three major enzymes involved in the inflammatory factors: cyclooxygenase (COX-2) and its product prostaglandin E2 (PGE-2), lipoxygenase (5-LOX), and inducible nitric oxide (iNOS), using immunocytochemistry and Western blotting analyses. It was found that the receptor phase at 24 h contained (0.8, 25, 1.8, 3 x 10(-3)) micromol mL(-1) of harpagoside, harpagide, verbascoside, 8-O-p-coumaroyl-harpagide, respectively. When applied to skin, this solution effectively inhibited the expression of COX-2 and its product PGE-2. However, it did not have a significant effect on either 5-LOX or iNOS compared to control samples (PBS only). These data support the hypothesis that the transcutaneous delivery of H. procumbens can treat inflammation in deeper tissues such as in arthritis. Moreover, a novel ex vivo model has been described for assessing the potential anti-inflammatory activity of permeants delivered to deeper subcutaneous regions.

  16. Peripheral Female Genital Arousal as Assessed by Thermography Following Topical Genital Application of Alprostadil vs Placebo Arousal Gel: A Proof-of-Principle Study Without Visual Sexual Stimulation

    Directory of Open Access Journals (Sweden)

    Sue W. Goldstein, BA, CCRC, IF

    2016-09-01

    Conclusion: Topical alprostadil administered to healthy premenopausal women induced statistically significant, sustained increases in genital temperatures of the vestibule, clitoris, and vulva within 20 minutes compared with OTC lubricant.

  17. The porosity assessment of thermal barrier coatings obtained by APS method

    Directory of Open Access Journals (Sweden)

    G. Moskal

    2007-01-01

    Full Text Available Purpose: The article presents the outline of methods and range of microstructural assessment of ceramiccoatings, using the example of thermal barrier coatings. The major structural parameters describing the qualityof the barrier layers have been characterised as well as the problems related to the correct metallographicspecimen preparation and the methodology of their assessment.Design/methodology/approach: A procedure of porosity assessment, employing quantative metallographicprinciples and automatic image analysis has been propounded, together with types of quantitative parametersand methods of their application.Findings: It was found that the application of the quantitative metallographic methods combined with automaticimage analysis can form an effective tool of both quantitative and qualitative assessment such parameters ofstructural ceramic layers as porosity.Research limitations/implications: This type of assessment enables obtaining more than just the absolute valueof the porosity of the given area: it provides the means for determining a number of other quantitative parameters,e.g. the surface area of the pores, their elongation and shape together with the whole statistical analysis.Practical implications: The application of scanning microscopy, especially observation techniques such as BSE,BSETOPO or BSE3D enables a precise differentiation of the areas constituting pores from other artefacts.Originality/value: Description of procedure of porosity assessments in APS TBC system by use of thequantitative metallographic methods combined with automatic image analysis, and possibility of applicationsspecial techniques of scanning microscopy.

  18. Diclofenac Topical (osteoarthritis pain)

    Science.gov (United States)

    Diclofenac topical gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the ... the knees, ankles, feet, elbows, wrists, and hands. Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain ...

  19. Thermal and structural assessments of a ceramic wafer seal in hypersonic engines

    Science.gov (United States)

    Tong, Mike T.; Steinetz, Bruce M.

    1991-01-01

    The thermal and structural performances of a ceramic wafer seal in a simulated hypersonic engine environment are numerically assessed. The effects of aerodynamic heating, surface contact conductance between the seal and its adjacent surfaces, flow of purge coolant gases, and leakage of hot engine flow path gases on the seal temperature were investigated from the engine inlet back to the entrance region of the combustion chamber. Finite element structural analyses, coupled with Weibull failure analyses, were performed to determine the structural reliability of the wafer seal.

  20. Thermal and structural assessments of a ceramic wafer seal in hypersonic engine

    Science.gov (United States)

    Tong, Mike; Steinetz, Bruce

    1991-01-01

    The thermal and structural performances of a ceramic wafer seal in a simulated hypersonic engine environment are numerically assessed. The effects of aerodynamic heating, surface contact conductance between the seal and its adjacent surfaces, flow of purge coolant gases, and leakage of hot engine flow path gases on the seal temperature were investigated from the engine inlet back to the entrance region of the combustion chamber. Finite element structural analyses, coupled with Weibull failure analyses, were performed to determine the structural reliability of the wafer seal.

  1. The deterministic structural integrity assessment of reactor pressure vessels under pressurized thermal shock loading

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Mingya, E-mail: chenmingya@cgnpc.com.cn; Lu, Feng; Wang, Rongshan; Huang, Ping; Liu, Xiangbin; Zhang, Guodong; Xu, Chaoliang

    2015-07-15

    Highlights: • The conservative and non-conservative assumptions in the codes were shown. • The influence of different loads on the SM was given. • The unloading effect of the cladding was studied. • A concentrated reflection of the safety was shown based on 3-D FE analyses. - Abstract: The deterministic structural integrity of a reactor pressure vessel (RPV) related to pressurized thermal shocks (PTSs) has been extensively studied. While the nil-ductility-transition temperature (RT{sub NDT}) parameter is widely used, the influence of fluence and temperature distributions along the thickness of the base metal wall cannot be reflected in the comparative analysis. This paper introduces the method using a structure safety margin (SM) parameter which is based on a comparison between the material toughness (the fracture initiation toughness K{sub IC} or fracture arrest toughness K{sub Ia}) and the stress intensity factor (SIF) along the crack front for the integrity analysis of a RPV subjected to PTS transients. A 3-D finite element model is used to perform fracture mechanics analyses considering both crack initiation assessment and arrest assessment. The results show that the critical part along the crack front is always the clad-base metal interface point (IP) rather than the deepest point (DP) for either crack initiation assessment or crack arrest assessment under the thermal load. It is shown that the requirement in Regulatory Guide 1.154 that ‘axial flaws with depths less than 20% of the wall thickness and all circumferential flaws should be modeled in infinite length’ may be non-conservative. As the assessment result is often poor universal for a given material, crack and transient, caution is recommended in the safety assessment, especially for the IP. The SIF reduces under the thermal or pressure load if the map cracking (MC) effect is considered. Therefore, the assumption in the ASME and RCCM codes that the cladding should be taken into account in

  2. Unsteady-state human-body exergy consumption rate and its relation to subjective assessment of dynamic thermal environments

    DEFF Research Database (Denmark)

    Schweiker, Marcel; Kolarik, Jakub; Dovjak, Mateja

    2016-01-01

    Few examples studied applicability of exergy analysis on human thermal comfort. These examples relate the human-body exergy consumption rate with subjectively obtained thermal sensation votes and had been based on steady-state calculation methods. However, humans are rarely exposed to steady......-state thermal environments. Therefore, the first objective of the current paper was to compare a recently introduced unsteady-state model with previously used steady-state model using data obtained under both constant and transient temperature conditions. The second objective was to explore a relationship...... between the human-body exergy consumption rate and subjective assessment of thermal environment represented by thermal sensation as well as to extend the investigation towards thermal acceptability votes. Comparison of steady-state and unsteady-state model showed that results from both models were...

  3. Syntacticized topics in Kurmuk

    DEFF Research Database (Denmark)

    Andersen, Torben

    2015-01-01

    This article argues that Kurmuk, a little-described Western Nilotic language, is characterized by a syntacticized topic whose grammatical relation is variable. In this language, declarative clauses have as topic an obligatory preverbal NP which is either a subject, an object or an adjunct....... The grammatical relation of the topic is expressed by a voice-like inflection of the verb, here called orientation. While subject-orientation is morphologically unmarked, object-oriented and adjunct-oriented verbs are marked by a subject suffix or by a suffix indicating that the topic is not subject, and adjunct......-orientation differs from object-orientation by a marked tone pattern. Topic choice largely reflects information structure by indicating topic continuity. The topic also plays a crucial role in relative clauses and in clauses with contrastive constituent focus, in that objects and adjuncts can only be relativized...

  4. Assessment of Outdoor Thermal Comfort and Wind Characteristics at Three Different Locations in Peninsular Malaysia

    Directory of Open Access Journals (Sweden)

    Hanipah Mohd Hafizal

    2016-01-01

    Full Text Available Urbanization and rapid growth in construction have led to the problems of global warming and urban heat island throughout the world. In order to reduce these problems particularly in hot and humid climatic region, a research on current level of outdoor thermal comfort and wind characteristics based on the local weather conditions around Malaysia should be conducted. This paper reports on the analysis of outdoor thermal comfort level at hottest temperatures and wind characteristics at three locations in Peninsular Malaysia by using hourly climatic data recorded by Malaysian Meteorological Department (MetMalaysia. The level of outdoor thermal comfort was assessed based on the Universal Thermal Climate Index (UTCI. The results showed extreme heat stress conditions have occurred at Alor Setar, Kuantan, and Subang with UTCI values of 51.2°C, 49.7°C, and 49.0°C respectively taking into account only temperature data from the year 2012 to 2014. However, for 20 years data from 1994 to 2014, the calculated UTCI also showed extreme heat stress conditions with their respective values of 49.6°C, 43.8°C, and 49.7°C for Alor Setar, Kuantan, and Subang respectively. Meanwhile, the hourly mean wind speed for three years data at Alor Setar, Kuantan, and Subang, were 1.70m/s, 1.69m/s, and 1.63m/s respectively. The highest mean wind speed of 11.6m/s was observed at Subang, while no wind movement (i.e. 0m/s was considered to be the lowest hourly wind speed for all three locations. The observed prevailing wind direction for all the three locations was from the north (0°. It can be concluded that Peninsular Malaysia is generally facing extreme heat stress problem due to unfavourable climatic conditions.

  5. Assessment of uncertainties of the models used in thermal-hydraulic computer codes

    Science.gov (United States)

    Gricay, A. S.; Migrov, Yu. A.

    2015-09-01

    The article deals with matters concerned with the problem of determining the statistical characteristics of variable parameters (the variation range and distribution law) in analyzing the uncertainty and sensitivity of calculation results to uncertainty in input data. A comparative analysis of modern approaches to uncertainty in input data is presented. The need to develop an alternative method for estimating the uncertainty of model parameters used in thermal-hydraulic computer codes, in particular, in the closing correlations of the loop thermal hydraulics block, is shown. Such a method shall feature the minimal degree of subjectivism and must be based on objective quantitative assessment criteria. The method includes three sequential stages: selecting experimental data satisfying the specified criteria, identifying the key closing correlation using a sensitivity analysis, and carrying out case calculations followed by statistical processing of the results. By using the method, one can estimate the uncertainty range of a variable parameter and establish its distribution law in the above-mentioned range provided that the experimental information is sufficiently representative. Practical application of the method is demonstrated taking as an example the problem of estimating the uncertainty of a parameter appearing in the model describing transition to post-burnout heat transfer that is used in the thermal-hydraulic computer code KORSAR. The performed study revealed the need to narrow the previously established uncertainty range of this parameter and to replace the uniform distribution law in the above-mentioned range by the Gaussian distribution law. The proposed method can be applied to different thermal-hydraulic computer codes. In some cases, application of the method can make it possible to achieve a smaller degree of conservatism in the expert estimates of uncertainties pertinent to the model parameters used in computer codes.

  6. Ocean Thermal Energy Conversion Life Cycle Cost Assessment, Final Technical Report, 30 May 2012

    Energy Technology Data Exchange (ETDEWEB)

    Martel, Laura [Lockheed Martin, Manassas, VA (United States); Smith, Paul [John Halkyard and Associates: Glosten Associates, Houston, TX (United States); Rizea, Steven [Makai Ocean Engineering, Waimanalo, HI (United States); Van Ryzin, Joe [Makai Ocean Engineering, Waimanalo, HI (United States); Morgan, Charles [Planning Solutions, Inc., Vancouver, WA (United States); Noland, Gary [G. Noland and Associates, Inc., Pleasanton, CA (United States); Pavlosky, Rick [Lockheed Martin, Manassas, VA (United States); Thomas, Michael [Lockheed Martin, Manassas, VA (United States); Halkyard, John [John Halkyard and Associates: Glosten Associates, Houston, TX (United States)

    2012-05-30

    The Ocean Thermal Energy Conversion (OTEC) Life Cycle Cost Assessment (OLCCA) is a study performed by members of the Lockheed Martin (LM) OTEC Team under funding from the Department of Energy (DOE), Award No. DE-EE0002663, dated 01/01/2010. OLCCA objectives are to estimate procurement, operations and maintenance, and overhaul costs for two types of OTEC plants: -Plants moored to the sea floor where the electricity produced by the OTEC plant is directly connected to the grid ashore via a marine power cable (Grid Connected OTEC plants) -Open-ocean grazing OTEC plant-ships producing an energy carrier that is transported to designated ports (Energy Carrier OTEC plants) Costs are developed using the concept of levelized cost of energy established by DOE for use in comparing electricity costs from various generating systems. One area of system costs that had not been developed in detail prior to this analysis was the operations and sustainment (O&S) cost for both types of OTEC plants. Procurement costs, generally referred to as capital expense and O&S costs (operations and maintenance (O&M) costs plus overhaul and replacement costs), are assessed over the 30 year operational life of the plants and an annual annuity calculated to achieve a levelized cost (constant across entire plant life). Dividing this levelized cost by the average annual energy production results in a levelized cost of electricity, or LCOE, for the OTEC plants. Technical and production efficiency enhancements that could result in a lower value of the OTEC LCOE were also explored. The thermal OTEC resource for Oahu, Hawaii and projected build out plan were developed. The estimate of the OTEC resource and LCOE values for the planned OTEC systems enable this information to be displayed as energy supplied versus levelized cost of the supplied energy; this curve is referred to as an Energy Supply Curve. The Oahu Energy Supply Curve represents initial OTEC deployment starting in 2018 and demonstrates the

  7. Correlation between subjective assessments of local thermal discomfort and thermal manikin measurements in a simulated aircraft cabin

    DEFF Research Database (Denmark)

    Zukowska, Daria; Strøm-Tejsen, Peter; Jama, Agnieszka;

    2005-01-01

    The thermal environment in a 21-seat simulated section of an aircraft cabin installed in a climate chamber was investigated. Using two thermal manikins and fourteen heated cylin-ders to represent passengers, measurements were carried out at cabin temperatures of 20.6°C, 23.3°C and 26.1°C (69°F, 74...

  8. Assessing the environmental impacts of freshwater thermal pollution from global power generation in LCA.

    Science.gov (United States)

    Raptis, Catherine E; Boucher, Justin M; Pfister, Stephan

    2017-02-15

    Freshwater heat emissions from power plants with once-through cooling systems constitute one of many environmental pressures related to the thermoelectric power industry. The objective of this work was to obtain high resolution, operational characterization factors (CF) for the impact of heat emissions on ecosystem quality, and carry out a comprehensive, spatially, temporally and technologically differentiated damage-based environmental assessment of global freshwater thermal pollution. The aggregation of CFs on a watershed level results in 12.5% lower annual impacts globally and even smaller differences for the most crucial watersheds and months, so watershed level CFs are recommended when the exact emission site within the basin is unknown. Long-range impacts account for almost 90% of the total global impacts. The Great Lakes, several Mississippi subbasins, the Danube, and the Yangtze are among the most thermally impacted watersheds globally, receiving heat emissions from predominantly coal-fuelled and nuclear power plants. Globally, over 80% of the global annual impacts come from power plants constructed during or before the 1980s. While the impact-weighted mean age of the power plants in the Mississippi ranges from 38 to 51years, in Chinese watersheds including the Yangtze, the equivalent range is only 15 to 22years, reflecting a stark contrast in thermal pollution mitigation approaches. With relatively high shares of total capacity from power plants with once-through freshwater cooling, and tracing a large part of the Danube, 1kWh of net electricity mix is the most impactful in Hungary, Bulgaria and Serbia. Monthly CFs are provided on a grid cell level and on a watershed level for use in Life Cycle Assessment. The impacts per generating unit are also provided, as part of our effort to make available a global dataset of thermoelectric power plant emissions and impacts.

  9. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    Science.gov (United States)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole community of the workshop, we thank the referees for their careful reading and useful suggestions which helped to improve all of the submitted papers. A brief description of CEWQO The Central European Workshop on Quantum Optics is a series of conferences started informally in Budapest in 1992. Sometimes small events transform into important conferences, as in the case of CEWQO. Professor Jozsef Janszky, from the Research Institute of Solid State Physics and Optics, is the founder of this series. Margarita Man'ko obtained the following information from Jozsef Janszky during her visit to Budapest, within the framework of cooperation between the Russian and Hungarian Academies of Sciences in 2005. He organized a small workshop on quantum optics in Budapest in 1992 with John Klauder as a main speaker. Then, bearing in mind that a year before Janszky himself was invited by Vladimir Buzek to give a seminar on the same topic in Bratislava, he decided to assign the name 'Central European Workshop on Quantum Optics', considering the seminar in Bratislava to be the first workshop and the one in Budapest the second. The third formal workshop took place in Bratislava in 1993 organized by Vladimir Buzek, then in 1994 (Budapest, by Jozsef Janszky), 1995 and 1996 (Budmerice, Slovakia, by Vladimir Buzek), 1997 (Prague, by Igor Jex), 1999 (Olomouc, Czech Republic, by Zdenek Hradil), 2000 (Balatonfüred, Hungary, by Jozsef Janszky ), 2001 (Prague, by Igor Jex), 2002 (Szeged, Hungary, by Mihaly Benedict), 2003 (Rostock,Germany, by Werner Vogel and

  10. Case study for model validation : assessing a model for thermal decomposition of polyurethane foam.

    Energy Technology Data Exchange (ETDEWEB)

    Dowding, Kevin J.; Leslie, Ian H. (New Mexico State University, Las Cruces, NM); Hobbs, Michael L.; Rutherford, Brian Milne; Hills, Richard Guy (New Mexico State University, Las Cruces, NM); Pilch, Martin M.

    2004-10-01

    A case study is reported to document the details of a validation process to assess the accuracy of a mathematical model to represent experiments involving thermal decomposition of polyurethane foam. The focus of the report is to work through a validation process. The process addresses the following activities. The intended application of mathematical model is discussed to better understand the pertinent parameter space. The parameter space of the validation experiments is mapped to the application parameter space. The mathematical models, computer code to solve the models and its (code) verification are presented. Experimental data from two activities are used to validate mathematical models. The first experiment assesses the chemistry model alone and the second experiment assesses the model of coupled chemistry, conduction, and enclosure radiation. The model results of both experimental activities are summarized and uncertainty of the model to represent each experimental activity is estimated. The comparison between the experiment data and model results is quantified with various metrics. After addressing these activities, an assessment of the process for the case study is given. Weaknesses in the process are discussed and lessons learned are summarized.

  11. Thermal Runaway Severity Reduction Assessment and Implementation: On Li-Ion Batteries

    Science.gov (United States)

    Darcy, Eric

    2015-01-01

    Preventing cell-cell thermal runaway propagation and flames/sparks from exiting battery enclosure is possible with proper thermal & electrical design and cell thermal runaway ejecta/effluent management and can be had with minimal mass/volume penalty.

  12. A Prospective, Descriptive Study to Assess the Clinical Benefits of Using Calendula officinalis Hydroglycolic Extract for the Topical Treatment of Diabetic Foot Ulcers.

    Science.gov (United States)

    Buzzi, Marcelo; de Freitas, Franciele; Winter, Marcos

    2016-03-01

    Diabetic foot ulcers (DFUs) have a significant impact on patient quality of life. A prospective, descriptive pilot study was conducted between May 2012 and December 2013 through the dermatology outpatient unit in a Brazilian hospital to evaluate the clinical benefits of using Calendula officinalis hydroglycolic extract in the treatment of DFUs. Patients diagnosed with a stable neuropathic ulcer of >3 months' duration; ranging in size from 0.5-40 cm(2); without osteomyelitis, gangrene, bone exposure, cancer, or deep tissue infection; ages 18-90 years; with adequate glycemic control and no history of an allergy to C. officinalis were enrolled. Patients provided demographic and diabetes-related information and were evaluated biweekly for 30 weeks or until healing (ie, full epithelialization with no wound drainage). DFUs were measured and clinically examined for microbiological flora and presence of odor, tissue type (eg, granulation, fibrin sloth, necrosis), exudate, and retraction rate using planimetry images. Patients' blood tests and neuropathic pain assessment (the latter by clinician-directed questionnaire) were performed at baseline and the end of treatment; pain also was assessed during dressing changes using a 10-point rating scale. Patients' ulcers were treated twice daily with C. officinalis hydroglycolic extract spray solution and covered with saline-moistened, sterile, nonadherent gauze and bandages followed by foot offloading with adequate protective footwear. Patients received their first treatment in the clinic then performed care at home. From a potential population of 109 patients, 25 did not meet the inclusion criteria. Of the remaining 84 participants enrolled, 43 withdrew before study completion; cited reasons included lost to follow-up (16), medical judgment (2), failure to attend >3 scheduled visits (17), protocol violation (5), and death (3). Forty-one (41) - 17 women, average age 62 years (range 44-82 years), average glycemic level 153 mg

  13. Processing of thermal parameters for the assessment of geothermal potential of sedimentary basins

    Science.gov (United States)

    Pasquale, V.; Chiozzi, P.; Gola, G.; Verdoya, M.

    2009-04-01

    The growing interest on renewable energy sources is stimulating new efforts aimed at the assessment of geothermal potential in several countries, and new developments are expected in the near future. In this framework, a basic step forward is to focus geothermal investigations on geological environments which so far have been relatively neglected. Some intracontinental sedimentary basins could reveal important low enthalpy resources. The evaluation of the geothermal potential in such geological contexts involves the synergic use of geophysical and hydrogeological methodologies. In sedimentary basins a large amount of thermal and hydraulic data is generally available from petroleum wells. Unfortunately, borehole temperature data are often affected by a number of perturbations which make very difficult determination of the true geothermal gradient. In this paper we addressed the importance of the acquisition of thermal parameters (temperature, geothermal gradient, thermal properties of the rock) and the technical processing which is necessary to obtain reliable geothermal characterizations. In particular, techniques for corrections of bottom-hole temperature (BHT) data were reviewed. The objective was to create a working formula usable for computing the undisturbed formation temperature for specific sedimentary basins. As test areas, we analysed the sedimentary basins of northern Italy. Two classical techniques for processing temperature data from oil wells are customarily used: (i) the method by Horner, that requires two or more measurements of bottom-hole temperatures carried out at the same depth but at different shut-in times te and (ii) the technique by Cooper and Jones, in which several physical parameters of the mud and formation need to be known. We applied both methods to data from a number of petroleum explorative wells located in two areas of the Po Plain (Apenninic buried arc and South Piedmont Basin - Pedealpine homocline). From a set of about 40 wells

  14. Seasonal differences in the subjective assessment of outdoor thermal conditions and the impact of analysis techniques on the obtained results

    Science.gov (United States)

    Kántor, Noémi; Kovács, Attila; Takács, Ágnes

    2016-03-01

    Wide research attention has been paid in the last two decades to the thermal comfort conditions of different outdoor and semi-outdoor urban spaces. Field studies were conducted in a wide range of geographical regions in order to investigate the relationship between the thermal sensation of people and thermal comfort indices. Researchers found that the original threshold values of these indices did not describe precisely the actual thermal sensation patterns of subjects, and they reported neutral temperatures that vary among nations and with time of the year. For that reason, thresholds of some objective indices were rescaled and new thermal comfort categories were defined. This research investigates the outdoor thermal perception patterns of Hungarians regarding the Physiologically Equivalent Temperature (PET) index, based on more than 5800 questionnaires. The surveys were conducted in the city of Szeged on 78 days in spring, summer, and autumn. Various, frequently applied analysis approaches (simple descriptive technique, regression analysis, and probit models) were adopted to reveal seasonal differences in the thermal assessment of people. Thermal sensitivity and neutral temperatures were found to be significantly different, especially between summer and the two transient seasons. Challenges of international comparison are also emphasized, since the results prove that neutral temperatures obtained through different analysis techniques may be considerably different. The outcomes of this study underline the importance of the development of standard measurement and analysis methodologies in order to make future studies comprehensible, hereby facilitating the broadening of the common scientific knowledge about outdoor thermal comfort.

  15. Seasonal differences in the subjective assessment of outdoor thermal conditions and the impact of analysis techniques on the obtained results

    Science.gov (United States)

    Kántor, Noémi; Kovács, Attila; Takács, Ágnes

    2016-11-01

    Wide research attention has been paid in the last two decades to the thermal comfort conditions of different outdoor and semi-outdoor urban spaces. Field studies were conducted in a wide range of geographical regions in order to investigate the relationship between the thermal sensation of people and thermal comfort indices. Researchers found that the original threshold values of these indices did not describe precisely the actual thermal sensation patterns of subjects, and they reported neutral temperatures that vary among nations and with time of the year. For that reason, thresholds of some objective indices were rescaled and new thermal comfort categories were defined. This research investigates the outdoor thermal perception patterns of Hungarians regarding the Physiologically Equivalent Temperature ( PET) index, based on more than 5800 questionnaires. The surveys were conducted in the city of Szeged on 78 days in spring, summer, and autumn. Various, frequently applied analysis approaches (simple descriptive technique, regression analysis, and probit models) were adopted to reveal seasonal differences in the thermal assessment of people. Thermal sensitivity and neutral temperatures were found to be significantly different, especially between summer and the two transient seasons. Challenges of international comparison are also emphasized, since the results prove that neutral temperatures obtained through different analysis techniques may be considerably different. The outcomes of this study underline the importance of the development of standard measurement and analysis methodologies in order to make future studies comprehensible, hereby facilitating the broadening of the common scientific knowledge about outdoor thermal comfort.

  16. Comparative assessment of the therapeutic effects of the topical and systemic forms of Hypericum perforatum extract on induced oral mucositis in golden hamsters.

    Science.gov (United States)

    Tanideh, N; Namazi, F; Andisheh Tadbir, A; Ebrahimi, H; Koohi-Hosseinabadi, O

    2014-10-01

    Oral mucositis is a common and irritating complication of chemotherapy and radiotherapy for malignancies. Current treatments have failed to achieve complete remission of this complication. The St. John's wort plant (Hypericum perforatum) has long been known for its anti-inflammatory and antibacterial effects. The current study was designed to investigate the therapeutic efficacy of the topical and systemic administration of H. perforatum extract on oral mucositis. Oral mucositis was induced in 72 male golden hamsters by administration of 5-fluorouracil (60mg/kg), on days 0, 5, and 10 of the study. The cheek pouch was scratched with a sterile needle on days 1 and 2. On days 12-17, H. perforatum extract topical gel 10%, oral H. perforatum extract (300mg/kg), and gel base groups were treated and then compared with a control group. Weights and blood samples were evaluated, biopsies from buccal lesions were examined histopathologically, and tissue malondialdehyde (MDA) was measured. Both of the H. perforatum extract treatment groups saw a significant relief in oral mucositis compared to the control and base gel groups; the systemic form was superior to the topical form. H. perforatum extract, administered orally or topically, expedited the healing of chemotherapy-induced oral mucositis in hamsters.

  17. GIS methodology and case study regarding assessment of the solar potential at territorial level: PV or thermal?

    Directory of Open Access Journals (Sweden)

    Loïc Quiquerez

    2015-06-01

    Full Text Available This paper presents a GIS-based methodology for assessing solar photovoltaic (PV and solar thermal potentials in urban environment. The consideration of spatial and temporal dimensions of energy resource and demand allows, for two different territories of the Geneva region, to determine the suitable building roof areas for solar installations, the solar irradiance on these areas and, finally, the electrical and/or thermal energy potentials related to the demand. Results show that the choice of combining PV and solar thermal for domestic hot water (DHW is relevant in both territories. Actually, the installation of properly sized solar thermal collectors doesn’t decrease much the solar PV potential, while allowing significant thermal production. However, solar collectors for combined DHW and space heating (SH require a much larger surface and, therefore, have a more important influence on the PV potential.

  18. Women's Health Topics

    Science.gov (United States)

    ... Health Diabetes Healthy Aging Heart Health Mammograms Caregiving Menopause Pregnancy Safe Medication Use Other Topics like cosmetics and nutrition Other Resources womenshealth.gov Federal Citizen Information Center ...

  19. [Topical therapy of rosacea].

    Science.gov (United States)

    Schöfer, H

    2013-07-01

    Metronidazole and azelaic acid are the only topical medications approved for rosacea. All other topical treatments for rosacea and its special forms are used off-label. Topical steroids are not indicated in rosacea, because of their side effects (induction of steroid rosacea, high risk of facial skin atrophy, and high risk of rebound after cessation of therapy). Topical as well as systemic steroids are allowed only as initial and short term therapy for acute forms of rosacea (e.g. rosacea fulminans). Papular and pustular rosacea is the major indication for topical therapy. Sebaceous gland and connective tissue hyperplasia in glandular-hypertrophic rosacea as well as erythema in erythematous rosacea do not respond well to topical measures. A new active substance, the alpha-2-adrenoreceptor agonist brimonidine, will be approved soon for the topical treatment of erythema in rosacea. All severe forms of rosacea should initially be treated with a combination of topical and systemic agents. After improvement of the clinical symptoms, topical treatment alone is usually adequate to maintain the control.

  20. Thermal record of the test tubes method used for small fibers assessment

    Directory of Open Access Journals (Sweden)

    Denny D. Collina

    2011-12-01

    Full Text Available In Brazil, the test that uses test tubes filled with cold water (25ºC and tubes filled with water heated to a temperature of 45ºC is recommended by the Ministry of Health as a way of evaluate thermal sensitivity on the injured skin of leprosy patients. The purpose of this work was to quantify the thermal stimulation applied to the skin, as well as the temperature variation of the heated water and of the tube's outer surface during stimulation sessions. The experiment had the participation of 14 healthy volunteers (31.2±11.4 years-old, ten of which were male (33.1±13.5 years-old and four were female (26.5±4.7 years-old. Three consecutive stimulation sessions were carried out, each of them with four stimuli. The maximum skin temperature at the end of the stimuli was measured at 35.8±0.6ºC. Such temperature values may be useful in the assessment of the loss of small fibers, which are responsible for the sensation of warmth.

  1. Uncertainty propagation in a 3-D thermal code for performance assessment of a nuclear waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Dutfoy, A. [Electricite de France (EDF), Research and Development Div., Safety and Reliability Branch, ESF, 92 - Clamart (France); Ritz, J.B. [Electricite de France (EDF), Research and Development Div., Fluid Mechanics and Heat Transfer, MFTT, 78 - Chatou (France)

    2001-07-01

    Given the very large time scale involved, the performance assessment of a nuclear waste repository requires numerical modelling. Because we are uncertain of the exact value of the input parameters, we have to analyse the impact of these uncertainties on the outcome of the physical models. The EDF Division Research and Development has set a reliability method to propagate these uncertainties or variability through models which requires much less physical simulations than the usual simulation methods. We apply the reliability method MEFISTO to a base case modelling the heat transfers in a virtual disposal in the future site of the French underground research laboratory, in the East of France. This study is led in collaboration with ANDRA which is the French Nuclear Waste Management Agency. With this exercise, we want to evaluate the thermal behaviour of a concept related to the variation of physical parameters and their uncertainty. (author)

  2. Alkyl polyglucoside-stabilized emulsion as a prospective vehicle for Usnea barbata CO2-supercritical extract: Assessing stability, safety and efficiency of a topical formulation

    Directory of Open Access Journals (Sweden)

    Žugić Ana R.

    2015-01-01

    Full Text Available Antimicrobial activity of Usnea barbata especially against bacteria involved in pathogenesis of various skin conditions has been well documented in literature. Nevertheless, there are no papers dealing with formulation of its isolates into topical preparations for treatment of skin infections. In present study, alkyl polyglucoside (APG - based vehicle was developed as carrier of U. barbata CO2-supercritical extract (U-SE that demonstrated the best antimicrobial potential in preliminary screening. For comparison, chosen extract in the same concentration and using the same procedure was incorporated into a pharmacopoeial vehicle. Comparative evaluation of physicochemical stability, efficiency and safety proved APG-based vehicle to possess certain preferential features as carrier of U-SE compared to the reference one, composing a topical formulation with potential clinical relevance in treatment of skin infections. [Projekat Ministarstva nauke Republike Srbije, br. III45017 i br. TR34031

  3. Topic Identification in Discourse

    CERN Document Server

    Chen, K

    1995-01-01

    This paper proposes a corpus-based language model for topic identification. We analyze the association of noun-noun and noun-verb pairs in LOB Corpus. The word association norms are based on three factors: 1) word importance, 2) pair co-occurrence, and 3) distance. They are trained on the paragraph and sentence levels for noun-noun and noun-verb pairs, respectively. Under the topic coherence postulation, the nouns that have the strongest connectivities with the other nouns and verbs in the discourse form the preferred topic set. The collocational semantics then is used to identify the topics from paragraphs and to discuss the topic shift phenomenon among paragraphs.

  4. Assessment of thermal bioclimate and tourism climate potential for central Europe—the example of Luxembourg

    Science.gov (United States)

    Matzarakis, Andreas; Rammelberg, Joscha; Junk, Jürgen

    2013-10-01

    Tourism destinations often require information about climate to assess their climate potential. This can be performed in terms of mean conditions of relevant climatological parameters. For a user-friendly analysis and visualization of climate data relevant for tourism application in Luxembourg, information is prepared based on the facets of climate in tourism. Information on thermal comfort/stress conditions as well as aesthetical and physical parameters is considered. In the present study, relevant and sensible factors were identified and presented. Therefore, physiologically equivalent temperature, precipitation patterns and the Climate-Tourism/Transfer-Information-Scheme are applied. In addition, extreme events relevant for heat stress are analysed based on existing data sets (i.e. heat waves of 2010). Expected climatic conditions for the future are investigated using the projections of two different regional climate models. The results concerning climate change conditions reveal increasing heat stress and sultriness but decreasing cold stress. This information is the basis for an adequate assessment to provide relevant information for different environmental planning issues as well as for the growing tourism sector of Luxembourg.

  5. Chemical, Thermal and Spectroscopic Methods to Assess Biodegradation of Winery-Distillery Wastes during Composting.

    Directory of Open Access Journals (Sweden)

    A Torres-Climent

    Full Text Available The objective of this work was to study the co-composting process of wastes from the winery and distillery industry with animal manures, using the classical chemical methods traditionally used in composting studies together with advanced instrumental methods (thermal analysis, FT-IR and CPMAS 13C NMR techniques, to evaluate the development of the process and the quality of the end-products obtained. For this, three piles were elaborated by the turning composting system, using as raw materials winery-distillery wastes (grape marc and exhausted grape marc and animal manures (cattle manure and poultry manure. The classical analytical methods showed a suitable development of the process in all the piles, but these techniques were ineffective to study the humification process during the composting of this type of materials. However, their combination with the advanced instrumental techniques clearly provided more information regarding the turnover of the organic matter pools during the composting process of these materials. Thermal analysis allowed to estimate the degradability of the remaining material and to assess qualitatively the rate of OM stabilization and recalcitrant C in the compost samples, based on the energy required to achieve the same mass losses. FT-IR spectra mainly showed variations between piles and time of sampling in the bands associated to complex organic compounds (mainly at 1420 and 1540 cm-1 and to nitrate and inorganic components (at 875 and 1384 cm-1, respectively, indicating composted material stability and maturity; while CPMAS 13C NMR provided semi-quantitatively partition of C compounds and structures during the process, being especially interesting their variation to evaluate the biotransformation of each C pool, especially in the comparison of recalcitrant C vs labile C pools, such as Alkyl /O-Alkyl ratio.

  6. Chemical, Thermal and Spectroscopic Methods to Assess Biodegradation of Winery-Distillery Wastes during Composting.

    Science.gov (United States)

    Torres-Climent, A; Gomis, P; Martín-Mata, J; Bustamante, M A; Marhuenda-Egea, F C; Pérez-Murcia, M D; Pérez-Espinosa, A; Paredes, C; Moral, R

    2015-01-01

    The objective of this work was to study the co-composting process of wastes from the winery and distillery industry with animal manures, using the classical chemical methods traditionally used in composting studies together with advanced instrumental methods (thermal analysis, FT-IR and CPMAS 13C NMR techniques), to evaluate the development of the process and the quality of the end-products obtained. For this, three piles were elaborated by the turning composting system, using as raw materials winery-distillery wastes (grape marc and exhausted grape marc) and animal manures (cattle manure and poultry manure). The classical analytical methods showed a suitable development of the process in all the piles, but these techniques were ineffective to study the humification process during the composting of this type of materials. However, their combination with the advanced instrumental techniques clearly provided more information regarding the turnover of the organic matter pools during the composting process of these materials. Thermal analysis allowed to estimate the degradability of the remaining material and to assess qualitatively the rate of OM stabilization and recalcitrant C in the compost samples, based on the energy required to achieve the same mass losses. FT-IR spectra mainly showed variations between piles and time of sampling in the bands associated to complex organic compounds (mainly at 1420 and 1540 cm-1) and to nitrate and inorganic components (at 875 and 1384 cm-1, respectively), indicating composted material stability and maturity; while CPMAS 13C NMR provided semi-quantitatively partition of C compounds and structures during the process, being especially interesting their variation to evaluate the biotransformation of each C pool, especially in the comparison of recalcitrant C vs labile C pools, such as Alkyl /O-Alkyl ratio.

  7. Neutron Tomography Using Mobile Neutron Generators for Assessment of Void Distributions in Thermal Hydraulic Test Loops

    Science.gov (United States)

    Andersson, P.; Bjelkenstedt, T.; Sundén, E. Andersson; Sjöstrand, H.; Jacobsson-Svärd, S.

    Detailed knowledge of the lateral distribution of steam (void) and water in a nuclear fuel assembly is of great value for nuclear reactor operators and fuel manufacturers, with consequences for both reactor safety and economy of operation. Therefore, nuclear relevant two-phase flows are being studied at dedicated thermal-hydraulic test loop, using two-phase flow systems ranging from simplified geometries such as heated circular pipes to full scale mock-ups of nuclear fuel assemblies. Neutron tomography (NT) has been suggested for assessment of the lateral distribution of steam and water in such test loops, motivated by a good ability of neutrons to penetrate the metallic structures of metal pipes and nuclear fuel rod mock-ups, as compared to e.g. conventional X-rays, while the liquid water simultaneously gives comparatively good contrast. However, these stationary test loops require the measurement setup to be mobile, which is often not the case for NT setups. Here, it is acknowledged that fast neutrons of 14 MeV from mobile neutron generators constitute a viable option for a mobile NT system. We present details of the development of neutron tomography for this purpose at the division of Applied Nuclear Physics at Uppsala University. Our concept contains a portable neutron generator, exploiting the fusion reaction of deuterium and tritium, and a detector with plastic scintillator elements designed to achieveadequate spatial and energy resolution, all mounted in a light-weight frame without collimators or bulky moderation to allow for a mobile instrument that can be moved about the stationary thermal hydraulic test sections. The detector system stores event-to-event pulse-height information to allow for discrimination based on the energy deposition in the scintillator elements.

  8. Advanced Topics in Aerodynamics

    DEFF Research Database (Denmark)

    Filippone, Antonino

    1999-01-01

    "Advanced Topics in Aerodynamics" is a comprehensive electronic guide to aerodynamics,computational fluid dynamics, aeronautics, aerospace propulsion systems, design and relatedtechnology. We report data, tables, graphics, sketches,examples, results, photos, technical andscientific literature...

  9. Thermal Assessment of Landsat-7 ETM+ Radiative Cooler in Instrument and Spacecraft Thermal Vacuum Tests and in Flight

    Science.gov (United States)

    Choi, Michael K.

    1999-01-01

    During the radiative cooler cool-down phase of the Landsat-7 Enhanced Thematic Mapper Plus (ETM+) instrument thermal vacuum test #3, the coldest temperature that the Cold Focal Plane Array (CFPA) achieved was 89.5 K. The cold stage/CFPA temperature decreased from 315 K to 89.5 K in 80 hours. In the spacecraft and instrument integrated thermal vacuum test, the cold stage/CFPA temperature decreased from 315 K to 86.9 K in 80 hours, and was still decreasing at a rate of 0.08 K/hr when the cool-down was terminated. The cool-down was faster, and a colder CFPA temperature was obtained. In flight, the cooler cool- down was even faster, and colder. The cold stage/CFPA temperature decreased from 315 K to 89.7 K in 33 hours, and was still decreasing at a rate of 1 K/hr when cool- down was terminated at 89.7 K. The factors that affected the ETM+ cooler cool-down are the radiation heat sink temperature for the cold stage and intermediate stage, parasitic radiation heat load to the cooler, parasitic conduction heat load to the cooler, and cooler outgas time preceding cooler cool-down.

  10. Supplemental topics on voids

    Energy Technology Data Exchange (ETDEWEB)

    Rood, H.J.

    1988-09-01

    Several topics concerning voids are presented, supplementing the report of Rood (1988). The discovery of the Coma supercluster and void and the recognition of the cosmological significance of superclusters and voids are reviewed. Galaxy redshift surveys and redshift surveys for the Abell clusters and very distant objects are discussed. Solar system and extragalactic dynamics are examined. Also, topics for future observational research on voids are recommended. 50 references.

  11. Assessment and forecast of changes of reservoir volumes due to thermal settling in permafrost areas of Russia

    Institute of Scientific and Technical Information of China (English)

    Ilja S.Sobol; Stanislav V.Sobol

    2014-01-01

    This paper presents the results of data analyses and assessments of field and theoretical researches on reservoir bed relief transformation due to thermal settling in the permafrost regions of Russia. The resulting changes (increases) of the total volumes of large and small reservoirs are quantified, of which information will be of great use in future reservoir design and exploitation.

  12. Development of Energy Efficient Technologies for Burning Coal in Modern Thermal Power Plants and Efficiency Assessment Tools

    Science.gov (United States)

    Dubrovskiy, Vitali; Zubova, Marina; Sedelnikov, Nikolai; Dihnova, Anna

    2016-02-01

    Universal ecological energy-efficient burner was described. The burner allows to burn different types of coal and lignite without the use of fuel oil for kindling the boiler. Efficiency assessment tools of the introduction of the burner for combustion of coal in modern thermal power plants were given.

  13. Development of Energy Efficient Technologies for Burning Coal in Modern Thermal Power Plants and Efficiency Assessment Tools

    Directory of Open Access Journals (Sweden)

    Dubrovskiy Vitali

    2016-01-01

    Full Text Available Universal ecological energy-efficient burner was described. The burner allows to burn different types of coal and lignite without the use of fuel oil for kindling the boiler. Efficiency assessment tools of the introduction of the burner for combustion of coal in modern thermal power plants were given.

  14. Topical treatment of melasma

    Directory of Open Access Journals (Sweden)

    Bandyopadhyay Debabrata

    2009-01-01

    Full Text Available Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma.

  15. TOPICAL TREATMENT OF MELASMA

    Science.gov (United States)

    Bandyopadhyay, Debabrata

    2009-01-01

    Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma. PMID:20101327

  16. Topical Drugs for Pain Relief

    Directory of Open Access Journals (Sweden)

    Anjali Srinivasan

    2015-03-01

    Full Text Available Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that require low plasma concentrations to achieve a therapeutic effect.

  17. Topical Drugs for Pain Relief

    OpenAIRE

    Anjali Srinivasan; Prashanth Shenai; Laxmikanth Chatra; Veena KM; Prasanna Kumar Rao

    2015-01-01

    Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that ...

  18. Implicit stage topics

    Directory of Open Access Journals (Sweden)

    Karen Lahousse

    2008-04-01

    Full Text Available Il a souvent été proposé que les éléments spatio-temporels en position initiale de phrase spécifient le cadre de l’événement dénoté par la proposition et ont une interprétation thématique ou topicale. Alors que les topiques spatio-temporels explicites ont souvent été étudiés, Erteschik-Schir (1997, 1999 propose l’idée que les topiques spatio-temporels, ou topiques scéniques (stage topics peuvent aussi être implicites.Dans cet article, nous offrons des arguments en faveur de la notion de topique scénique implicite. Nous montrons qu’un certain nombre de cas d’inversion nominale en français, une configuration syntaxique qui est favorisée par la présence d’un topique scénique explicite, s’expliquent par la présence d’un topique scénique implicite. Le fait que les topiques scéniques implicites interagissent avec la structure syntaxique de la même façon que les topiques scéniques explicites constitue un argument empirique en faveur de leur existence.It has often been proposed that sentence-initial spatio-temporal elements specify the frame in which the whole proposition takes place and are topical (i.e. thematic. Whereas considerable attention has been paid to explicit spatio-temporal topics, Erteschik-Shir (1997, 1999 argues that spatio-temporal topics, or stage topics, can also be implicit.In this article we provide evidence in favour of the notion of implicit stage topic. We show that a certain number of nominal inversion cases in French, a syntactic configuration which is triggered by the presence of an explicit stage topic, are explained by the presence of an implicit stage topic. The fact that implicit stage topics interact with syntactic structure the same way explicit stage topics do constitutes a strong empirical argument in favour of their existence.

  19. A Novel Algorithm for the Assessment of Blood-Brain Barrier Permeability Suggests That Brain Topical Application of Endothelin-1 Does Not Cause Early Opening of the Barrier in Rats

    Directory of Open Access Journals (Sweden)

    D. Jorks

    2011-01-01

    Full Text Available There are a number of different experimental methods for ex vivo assessment of blood-brain barrier (BBB opening based on Evans blue dye extravasation. However, these methods require many different steps to prepare the brain and need special equipment for quantification. We here report a novel, simple, and fast semiquantitative algorithm to assess BBB integrity ex vivo. The method is particularly suitable for cranial window experiments, since it keeps the spatial information about where the BBB opened. We validated the algorithm using sham controls and the established model of brain topical application of the bile salt dehydrocholate for early BBB disruption. We then studied spreading depolarizations in the presence and the absence of the vasoconstrictor endothelin-1 and found no evidence of early BBB opening (three-hour time window. The algorithm can be used, for example, to assess BBB permeability ex vivo in combination with dynamic in vivo studies of BBB opening.

  20. Spatial resolution effects on the assessment of evapotranspiration in olive orchards using high resolution thermal imagery

    Science.gov (United States)

    Santos, Cristina; Zarco-Tejada, Pablo J.; Lorite, Ignacio J.; Allen, Richard G.

    2013-04-01

    The use of remote sensing techniques for estimating surface energy balance and water consumption has significantly improved the characterization of the agricultural systems by determining accurate information about crop evapotranspiration and stress, mainly for extensive crops. However the use of these methodologies for woody crops has been low due to the difficulty in the accurate characterization of these crops, mainly caused by a coarse resolution of the imagery provided by the most widely used satellites (such as Landsat 5 and 7). The coarse spatial resolution provided by these satellite sensors aggregates into a single pixel the tree crown, sunlit and shaded soil components. These surfaces can each exhibit huge differences in temperature, albedo and vegetation indexes calculated in the visible, near infrared and short-wave infrared regions. Recent studies have found that the use of energy balance approaches can provide useful results for non-homogeneous crops (Santos et al., 2012) but detailed analysis is required to determine the effect of the spatial resolution and the aggregation of the scene components in these heterogeneous canopies. In this study a comparison between different spatial resolutions has been conducted using images from Landsat 7 (with thermal resolution of 60m) and from an airborne thermal (with resolution of 80 cm) flown over olive orchards at different dates coincident with the Landsat overpass. The high resolution thermal imagery was resampled at different scales to generate images with spatial resolution ranging from 0.8 m up to 120m (thermal resolution for Landsat 5 images). The selection of the study area was made to avoid those areas with missing Landsat 7 data caused by SLC-off gaps. The selected area has a total area of around 2500 ha and is located in Southern Spain, in the province of Malaga. The selected area is mainly cultivated with olive orchards with different crop practices (rainfed, irrigated, high density, young and adult

  1. Solar thermal technologies benefits assessment: Objectives, methodologies and results for 1981

    Science.gov (United States)

    Gates, W. R.

    1982-07-01

    The economic and social benefits of developing cost competitive solar thermal technologies (STT) were assessed. The analysis was restricted to STT in electric applications for 16 high insolation/high energy price states. Three fuel price scenarios and three 1990 STT system costs were considered, reflecting uncertainty over fuel prices and STT cost projections. After considering the numerous benefits of introducing STT into the energy market, three primary benefits were identified and evaluated: (1) direct energy cost savings were estimated to range from zero to $50 billion; (2) oil imports may be reduced by up to 9 percent, improving national security; and (3) significant environmental benefits can be realized in air basins where electric power plant emissions create substantial air pollution problems. STT research and development was found to be unacceptably risky for private industry in the absence of federal support. The normal risks associated with investments in research and development are accentuated because the OPEC cartel can artificially manipulate oil prices and undercut the growth of alternative energy sources.

  2. Metallic Thermal Protection System Technology Development: Concepts, Requirements and Assessment Overview

    Science.gov (United States)

    Dorsey, John T.; Poteet, Carl C.; Chen, Roger R.; Wurster, Kathryn E.

    2002-01-01

    A technology development program was conducted to evolve an earlier metallic thermal protection system (TPS) panel design, with the goals of: improving operations features, increasing adaptability (ease of attaching to a variety of tank shapes and structural concepts), and reducing weight. The resulting Adaptable Robust Metallic Operable Reusable (ARMOR) TPS system incorporates a high degree of design flexibility (allowing weight and operability to be traded and balanced) and can also be easily integrated with a large variety of tank shapes, airframe structural arrangements and airframe structure/material concepts. An initial attempt has been made to establish a set of performance based TPS design requirements. A set of general (FARtype) requirements have been proposed, focusing on defining categories that must be included for a comprehensive design. Load cases required for TPS design must reflect the full flight envelope, including a comprehensive set of limit loads, However, including additional loads. such as ascent abort trajectories, as ultimate load cases, and on-orbit debris/micro-meteoroid hypervelocity impact, as one of the discrete -source -damage load cases, will have a significant impact on system design and resulting performance, reliability and operability. Although these load cases have not been established, they are of paramount importance for reusable vehicles, and until properly included, all sizing results and assessments of reliability and operability must be considered optimistic at a minimum.

  3. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature...... is largely ignored by the critics. Thus, the article tests how topics may work in creative nonfiction. Two Danish bestsellers belonging to the genre, Frank’s Mit smukke genom ( My Beautiful Genome), about genomics, and Buk-Swienty’s Slagtebænk Dybbøl ( ‘Slaughter-bench Dybbøl’), a history book, are chosen...... as cases and analysed using a slightly modified motif model by Johansen. The result is that in both books the main topic is treated from a double perspective, but also that six out of seven secondary topics, or motifs, are treated as well. It is concluded that also in a topical sense creative nonfiction...

  4. Topical ketoprofen patch.

    Science.gov (United States)

    Mazières, Bernard

    2005-01-01

    Although oral nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of a variety of acute and chronic pain conditions, their use may be associated with serious systemic adverse effects, particularly gastrointestinal disorders. In order to minimise the incidence of systemic events related to such agents, topical NSAIDs have been developed. Topical NSAIDs, applied as gels, creams or sprays, penetrate the skin, subcutaneous fatty tissue and muscle in amounts that are sufficient to exert a therapeutic effect on peripheral and central mechanisms in the absence of high plasma concentrations. Data indicate that topical NSAIDs are effective at relieving pain in a number of acute and chronic pain indications. This review article discusses the pharmacokinetics, efficacy and tolerability of a new formulation of ketoprofen available as a topical patch. The topical patch containing ketoprofen 100mg as the active principle has been developed using a novel delivery system that dispenses therapeutic doses of the drug directly to the site of injury. Pharmacokinetic data indicate that although plasma levels of ketoprofen are higher when the drug is administered as a patch versus a gel, the total systemic bioavailability of ketoprofen 100 mg administered via a patch is no more than 10% of that reported for ketoprofen 100 mg administered orally. Because the patch facilitates ketoprofen delivery over a 24-hour period, the drug remains continually present in the tissue subjacent to the site of application. High tissue but low plasma ketoprofen concentrations mean that while tissue concentrations are high enough to exert a therapeutic effect, plasma concentrations remain low enough to not result in systemic adverse events caused by elevated serum NSAID levels. Phase III clinical trials in patients with non-articular rheumatism and traumatic painful soft tissue injuries showed that the topical ketoprofen patch was significantly more effective than placebo at

  5. Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment.

    Science.gov (United States)

    Garg, Bhawna Jain; Garg, Neeraj K; Beg, Sarwar; Singh, Bhupinder; Katare, Om Prakash

    2016-01-01

    The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo. The ethosomes were prepared by central composite design (CCD) and characterized for various quality attributes like vesicle shape, size, zeta potential, lamellarity, drug entrapment and drug leaching. The optimized ethosomes were subsequently incorporated int Carbopol® 934 gel and characterized for drug content, rheological behavior, texture profile, in vitro release, ex vivo skin permeation and retention, skin photosensitization and histopathological examination. Ethosomes were found to be spherical and multilamellar in structures having nanometric size range with narrow size distribution, and high encapsulation efficiency. Ethosomal formulations showed significant skin permeation and accumulation in the epidermal and dermal layers. The fluorescence microscopy study using 123 Rhodamine exhibited enhanced permeation of the drug-loaded ethosomes in the deeper layers of skin. Also, the developed formulation showed insignificant phototoxicity and erythema vis-à-vis the conventional cream. The results were cross-validated using histopathological examination of skin segments. In a nutshell, the ethosomes-based hydrogel formulation was found to be a promising drug delivery system demonstrating enhanced percutaneous penetration of methoxsalen with reduced phototoxicity and erythema, thus leading to improved patient compliance for the treatment against vitiligo.

  6. Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment.

    Science.gov (United States)

    Garg, Bhawna Jain; Garg, Neeraj K; Beg, Sarwar; Singh, Bhupinder; Katare, Om Prakash

    2016-03-01

    The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo. The ethosomes were prepared by central composite design (CCD) and characterized for various quality attributes like vesicle shape, size, zeta potential, lamellarity, drug entrapment and drug leaching. The optimized ethosomes were subsequently incorporated int Carbopol® 934 gel and characterized for drug content, rheological behavior, texture profile, in vitro release, ex vivo skin permeation and retention, skin photosensitization and histopathological examination. Ethosomes were found to be spherical and multilamellar in structures having nanometric size range with narrow size distribution, and high encapsulation efficiency. Ethosomal formulations showed significant skin permeation and accumulation in the epidermal and dermal layers. The fluorescence microscopy study using 123 Rhodamine exhibited enhanced permeation of the drug-loaded ethosomes in the deeper layers of skin. Also, the developed formulation showed insignificant phototoxicity and erythema vis-à-vis the conventional cream. The results were cross-validated using histopathological examination of skin segments. In a nutshell, the ethosomes-based hydrogel formulation was found to be a promising drug delivery system demonstrating enhanced percutaneous penetration of methoxsalen with reduced phototoxicity and erythema, thus leading to improved patient compliance for the treatment against vitiligo.

  7. Time- and Site-Dependent Life Cycle Assessment of Thermal Waste Treatment

    Energy Technology Data Exchange (ETDEWEB)

    Hellweg, Stefanie; Hofstetter, Thomas B.; Hungerbuehler, Konrad [Swiss Federal Inst. of Technology (ETH), Zuerich (Switzerland). Chemical Engineering Dept.

    2002-12-01

    The high living standard of many industrial countries has directly lead to an increase in the amount of municipal solid waste generated. Parallel to this increase in waste, there has been a raising demand for environmentally benign waste treatment processes. In Switzerland, the predominant way of treatment is incineration. Since the environmental impact of waste incineration depends on the technology used, a comprehensive assessment of the different thermal processes is necessary. In order to determine the environmental impact, we propose a model that quantifies the emissions and resource use resulting from the incineration of waste using different technologies, the landfills for the incineration residues, the transport of waste, related infrastructure, as well as the production of ancillary products. Using the Life-Cycle Assessment (LCA) methodology, we performed a case study that compared the conventional grate technology to new high temperature processes recovering metals and vitrifying the incineration residues. The results show that if the plant is equipped with a modern gas purification system the incineration process itself is not a key environmental problem of the system considered. Using the energy gained from waste incineration as the functional unit, the environmental impacts of incineration plants are comparable to that of a conventional power plant. If long-term time horizons are considered, the critical aspect is the release of heavy metals from the landfilled incineration residues. Due to the better quality of the solid outputs new technologies have a lower potential for environmental impact than the conventional grate technology. This, however, depends on the time horizon considered. With a temporal system boundary of 100 years, the grate technology appears better, because new technologies generally use more energy and short-term emissions are of minor importance no matter what technology is used. The evaluation of waste incineration technologies

  8. A combination of thermal methods to assess coronary pressure and flow dynamics with a pressure-sensing guide wire.

    Science.gov (United States)

    van der Horst, Arjen; Van't Veer, Marcel; van der Sligte, Robin A M; Rutten, Marcel C M; Pijls, Nico H J; van de Vosse, Frans N

    2013-03-01

    Measurement of coronary pressure and absolute flow dynamics have shown great potential in discerning different types of coronary circulatory disease. In the present study, the feasibility of assessing pressure and flow dynamics with a combination of two thermal methods, developed in combination with a pressure-sensor-tipped guide wire, was evaluated in an in vitro coronary model. A continuous infusion thermodilution method was employed to determine the average flow, whereas a thermal anemometric method was utilized to assess the pressure and flow dynamics, simultaneously. In the latter method, the electrical power supplied to an element, kept at constant temperature above ambient temperature, was used as a measure for the shear rate. It was found that, using a single calibration function, the method was able to assess coronary pressure and flow dynamics for different flow amplitudes, heart rates, and different pressure wires. However, due to the fact that the thermal anemometric method cannot detect local shear rate reversal, the method was unable to reliably measure flow dynamics close to zero. Nevertheless, the combined methodology was able to reliably assess diastolic hemodynamics. The diastolic peak flow and average diastolic resistance could be determined with a small relative error of (8 ± 7)% and (7 ± 5)%, respectively.

  9. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature i...

  10. Selected topics in magnetism

    CERN Document Server

    Gupta, L C

    1993-01-01

    Part of the ""Frontiers in Solid State Sciences"" series, this volume presents essays on such topics as spin fluctuations in Heisenberg magnets, quenching of spin fluctuations by high magnetic fields, and kondo effect and heavy fermions in rare earths amongst others.

  11. Contrastive topics decomposed

    Directory of Open Access Journals (Sweden)

    Michael Wagner

    2012-12-01

    Full Text Available The analysis of contrastive topics introduced in Büring 1997b and further developed in Büring 2003 relies on distinguishing two types of constituents that introduce alternatives: the sentence focus, which is marked by a FOC feature, and the contrastive topic, which is marked by a CT feature. A non-compositional rule of interpretation that refers to these features is used to derive a topic semantic value, a nested set of sets of propositions. This paper presents evidence for a correlation between the restrictive syntax of nested focus operators and the syntax of contrastive topics, a correlation which is unexpected under this analysis. A compositional analysis is proposed that only makes use of the flatter focus semantic values introduced by focus operators. The analysis aims at integrating insights from the original analysis while at the same time capturing the observed syntactic restrictions. http://dx.doi.org/10.3765/sp.5.8 BibTeX info

  12. Topics in Nonlinear Dynamics

    DEFF Research Database (Denmark)

    Mosekilde, Erik

    Through a significant number of detailed and realistic examples this book illustrates how the insights gained over the past couple of decades in the fields of nonlinear dynamics and chaos theory can be applied in practice. Aomng the topics considered are microbiological reaction systems, ecological...

  13. Topics for Mathematics Clubs.

    Science.gov (United States)

    Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

    The ten chapters in this booklet cover topics not ordinarily discussed in the classroom: Fibonacci sequences, projective geometry, groups, infinity and transfinite numbers, Pascal's Triangle, topology, experiments with natural numbers, non-Euclidean geometries, Boolean algebras, and the imaginary and the infinite in geometry. Each chapter is…

  14. IR thermography applied to the assessment of thermal conductivity of building materials

    Science.gov (United States)

    Bison, P.; Grinzato, E.

    2010-05-01

    A device to measure thermal conductivity of small specimens is presented. The specimen is sandwiched between two thermoelectric cells, one sources heat the other sink it. An infrared camera looks at the device and specimen on its side, determining both the heat flux flowing through it and the temperature gradient due to the unknown thermal resistance. The thermal conductivity is quickly recovered, as soon as the steady thermal regime is reached. The heat flux toward the environment is evaluated and minimized working at zero mean temperature difference. A couple of specimens made of materials used to prepare radiant heating floor screeds are measured. The Maxwell model to determine the thermal conductivity of mixture, based on the knowledge of the conductivity of the different phases and their volume fraction, is used to interpret the results.

  15. Optimizing the Environmental Performance of In Situ Thermal Remediation Technologies Using Life Cycle Assessment

    DEFF Research Database (Denmark)

    Lemming, Gitte; Nielsen, Steffen G.; Weber, Klaus

    2013-01-01

    to 75%. Moreover, a number of technology-specific improvements were identified, for instance by the substitution of stainless steel types in wells, heaters, and liners used in thermal conduction heating, thus reducing the nickel consumption by 45%. The combined effect of introducing all the suggested......In situ thermal remediation technologies provide efficient and reliable cleanup of contaminated soil and groundwater, but at a high cost of environmental impacts and resource depletion due to the large amounts of energy and materials consumed. This study provides a detailed investigation of four...... in situ thermal remediation technologies (steam enhanced extraction, thermal conduction heating, electrical resistance heating, and radio frequency heating) in order to (1) compare the life-cycle environmental impacts and resource consumption associated with each thermal technology, and (2) identify...

  16. Design of a novel prosthetic socket: assessment of the thermal performance.

    Science.gov (United States)

    Webber, Christina M; Davis, Brian L

    2015-05-01

    Prosthetic liners and sockets insulate the residual limb, causing excessive sweating and concomitant skin maceration. When coupled with atypical loading conditions, further dermatologic problems can arise. This can significantly reduce the quality of life of an amputee patient. Improving the design of the prosthetic socket has been proposed as a means of reestablishing a normal thermal environment around the residual limb. In this study, a prosthetic socket was modified by incorporating a helical cooling channel within the socket wall using additive manufacturing techniques. Two sockets were modeled: a control socket, and a modified socket containing a 0.48 cm diameter cooling channel. Computer simulations and bench-top testing were used to assess the design's ability to create a greater temperature differential across the socket wall. A greater temperature drop across the socket wall suggested that the socket could provide cooling benefits to the residual limb by allowing for heat to be drawn away from the limb. The temperature difference across the socket wall was calculated for both sockets in each aspect of the study. Both socket type (p=0.002) and location on the socket (p=0.014) were statistically significant factors affecting the temperature difference between inner and outer socket walls. Compared with the control socket, the modified socket containing a helical cooling channel exhibited greater temperature differences across its wall of 11.1 °C and 6.4 °C in the computer simulations and bench-top testing, respectively. This finding suggested that socket modifications, such as the cooling channel presented, could provide a beneficial cooling effect to an amputee patient's residual limb.

  17. Thermal Comfort Assessment and Optimization of Environmental Factors by Using Taguchi Method

    Directory of Open Access Journals (Sweden)

    A. R. Ismail

    2009-01-01

    Full Text Available Problem statement: The objective of this study was to determine the dominance effects of environmental factors such as Illuminance (lux, relative humidity (% and WBGT (°C on the operators’ productivity at Malaysian automotive industry. Approach: One automotive parts assembly factory had been chosen as a subject for the study. The subjects were workers at the assembly section of the factory. The environment examined was the Illuminance (lux, relative humidity (% and WBGT (°C of the surrounding workstation area. Two sets of representative data including the Illuminance, relative humidity (% and WBGT (°C level and production rate were collected during the study. All the data was measured using Babuc apparatus which is capable to measure simultaneously those mentioned environmental factors. The time series data of fluctuating level of environmental were plotted to identify the significant changes of factors. Then Taguchi Method was being utilized to find the sequence of dominance factors that contributed to the productivity of operator at the specified production workstation. From there, optimum level for the three factors will be determine for optimum productivity. Further multiple linear regressions were employed to obtain the equation model in order to represent the relationship of these environmental factors towards productivity. Results: The thermal comfort assessments of this station which was the scale PMV was 2 and PPD is 79% ware likely to be satisfied by the worker. Conclusion: The study revealed that the dominant factor contribute to the productivity at the body assembly production line is WBGT and Illuminance whereas the empirical finding was closely related to the perception study by survey questionnaire distribution.

  18. Experimental Assays to Assess the Efficacy of Vinegar and Other Topical First-Aid Approaches on Cubozoan (Alatina alata Tentacle Firing and Venom Toxicity

    Directory of Open Access Journals (Sweden)

    Angel A. Yanagihara

    2016-01-01

    Full Text Available Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that (1 recapitulate live-tentacle stings; (2 allow quantitation and imaging of cnidae discharge; (3 allow primary quantitation of venom toxicity; and (4 employ rigorous controls. We report the implementation of an integrated array of three experimental approaches designed to meet the above-stated criteria. Mechanistically overlapping, yet distinct, the three approaches comprised (1 direct application of test solutions on live tentacles (termed tentacle solution assay, or TSA with single image- and video-microscopy; (2 spontaneous stinging assay using freshly excised tentacles overlaid on substrate of live human red blood cells suspended in agarose (tentacle blood agarose assays, or TBAA; and (3 a “skin” covered adaptation of TBAA (tentacle skin blood agarose assay, or TSBAA. We report the use and results of these assays to evaluate the efficacy of topical first-aid approaches to inhibit tentacle firing and venom activity. TSA results included the potent stimulation of massive cnidae discharge by alcohols but only moderate induction by urine, freshwater, and “cola” (carbonated soft drink. Although vinegar, the 40-year field standard of first aid for the removal of adherent tentacles, completely inhibited cnidae firing in TSA and TSBAA ex vivo models, the most striking inhibition of both tentacle firing and subsequent venom-induced hemolysis was observed using newly-developed proprietary formulations (Sting No More™ containing copper gluconate, magnesium sulfate, and urea.

  19. The effect of thermal quality on the thermoregulatory behavior of the bearded dragon Pogona vitticeps: influences of methodological assessment.

    Science.gov (United States)

    Cadena, Viviana; Tattersall, Glenn J

    2009-01-01

    Metabolic functions are generally optimized within a narrow range of body temperatures (T(b)'s), conferring thermoregulation great importance to the survival and fitness of an animal. In lizards, T(b) regulation is mainly behavioral, and the metabolic costs associated with behavioral thermoregulation are primarily locomotory. In reptiles, however, it has been proposed that they thermoregulate less precisely when the associated costs, metabolic or otherwise, are high. Such a strategy enhances fitness by allowing lizards to be more flexible to changing environmental conditions while maximizing the benefits of maintaining a high T(b) and minimizing energy expenditure. We evaluated the behavioral thermoregulation of inland bearded dragons Pogona vitticeps under various thermal quality conditions requiring different locomotory investment for thermoregulation. The selected ambient temperature and preferred T(b) ranges increased at lower environmental thermal qualities, indicating a decrease in thermoregulatory precision in environments where the costs associated with thermoregulation were high. The level of thermoregulation was also affected, exhibiting a decrease in preferred T(b) of approximately 2 degrees C at the lowest-thermal-quality treatment. These data provide important implications for the procedural assessment of preferred T(b) and a better understanding of thermal set points in reptiles in general. Our results emphasize that the precise maintenance and assessment of preferred T(b) is contingent on the quality of the environment, laboratory or natural, that the animal inhabits.

  20. Assessment of some soil thermal conductivity models via variations in temperature and bulk density at low moisture range

    Science.gov (United States)

    Mahdavi, Seyed Mohamad; Neyshabouri, Mohammad Reza; Fujimaki, Haruyuki

    2016-08-01

    Simulation of heat transfer in soil under steady and unsteady situations requires reliable estimate of soil thermal conductivity (λ) at varying environmental conditions. In the current work several soil thermal conductivity predicting models including I) de Vries, II) Campbell, III) combined de Vries and Campbell and IV) de Vries-Nobre were evaluated for the four soils of coarse sand, sandy loam, loam and clay loam textured at varying in temperature and bulk density at low moisture range. Thermal conductivities measured by the cylindrical probe method served as the reference for models assessment. Results showed that approximately same thermal conductivities obtained by the five methods at low moisture range (θ ≤ 0.05 m3/m3). Also the de Vries and de Vries-Campbell models produced accurate than Campbell and de vries-Nobre models. The accuracy of the two models increased with soil compaction but decreased with temperature rise. Campbell model showed more reliability at higher (311.16 and 321.16 K) temperatures; but its accuracy declined with soil compaction in current work. It seems that assuming needle shape for the soil particles is far away from the reality whereas assuming spherical shapes may be more realistic and produced more satisfactory prediction of thermal conductivity. The compaction would alter particle arrangement and may increase the contact area of particles; and then make them behave more or less spherical shape.it seems thermal conductivity in solid particles increase via increasing in temperature. Since a modified mineral shape factor, g m , was developed as a combination between sphere and needle according to geometric mean particle diameter as well as bulk density and temperature as modifying factors. This factor increased the accuracy of de Vries-Nobre model up to 10.37%. Regarding nonlinear regression model, moisture content, bulk density, temperature and quartz content demonstrated significant effect on soil thermal conductivity in our

  1. The assessment of microbiological purity of selected components of animal feeds and mixtures which underwent thermal processing

    OpenAIRE

    SOBCZAK, Paweł; ZAWIŚLAK, Kazimierz; ŻUKIEWICZ-SOBCZAK, Wioletta; Jacek Mazur; Rafał Nadulski; Kozak, Marta

    2016-01-01

    Microorganisms which contaminate animal feeds pose a threat not only to animals but also indirectly to humans through their consumption of products of animal origin. The aim of the present study was to assess microbiological cleanness of selected resources and ready-made feed mixtures before and after thermal processing. The results indicated that the most bacteriologically contaminated resources were oats (Avena sativa), wheat middlings, wheat (Triticum vulgare), and poultry feed mixture KDK...

  2. Ukraine; Financial System Stability Assessment, including Reports on the Observance of Standards and Codes on the following topics: Monetary and Financial Policy Transparency, Banking Supervision, and Payment Systems

    OpenAIRE

    International Monetary Fund

    2003-01-01

    This Financial System Stability Assessment paper for Ukraine reviews financial sector issues and highlights macroeconomic developments, vulnerabilities, and soundness of the financial system. It discusses creditors' rights, insolvency, and corporate governance, and Anti-Money Laundering and Combating of Financing Terrorism. It provides information on the observance of international standards and codes, and the compliance with the Basel Core Principle for Effective Banking. It also reviews Ukr...

  3. Performance Assessment of Low-Temperature Thermal Storage with Electromagnetic Control

    Directory of Open Access Journals (Sweden)

    Ya-Wei Lee

    2014-08-01

    Full Text Available This study presents electromagnetic-controlled thermal storage (ECTS that can be directly implemented in strategies of low-temperature waste heat recovery for energy-consuming equipment. A magnetic nanofluid (MNF prepared from fine iron ferrite ferromagnetic particles is recommended as a latent heat medium (LHM. During electromagnetic induction, local flow fluctuations are generated and thermal convection in the MNF can be enhanced. The achieved results demonstrated that ECTS has a wide operational range and an optimum storage efficiency of 84.46%. Thus, a self-perturbation mode used to enhance thermal energy transportation can be designed for numerous waste heat management applications.

  4. Bench Scale Process for Low Cost CO2 Capture Using a Phase-Changing Absorbent: Topical Report EH&S Risk Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Westendorf, Tiffany; Farnum, Rachel; Perry, Robert; Herwig, Mark; Giolando, Salvatore; Green, Dianne; Morall, Donna

    2016-05-11

    GE Global Research was contracted by the Department of Energy to design and build a bench-scale process for a novel phase-changing aminosilicone-based CO2 capture solvent (award number DEFE0013687). As part of this program, a technology EH&S assessment (Subtask 5.1) has been completed for a CO2 capture system for a 550 MW coal-fired power plant. The assessment focuses on two chemicals used in the process, the aminosilicone solvent, GAP-0, and dodecylbenzenesulfonic acid (DDBSA), the GAP-0 carbamate formed upon reaction of the GAP-0 with CO2, and two potential byproducts formed in the process, GAP-0/SOx salts and amine-terminated, urea-containing silicone (also referred to as “ureas” in this report). The EH&S assessment identifies and estimates the magnitude of the potential air and water emissions and solid waste generated by the process and reviews the toxicological profiles of the chemicals associated with the process. Details regarding regulatory requirements, engineering controls, and storage and handling procedures are also provided in the following sections.

  5. Assessing District Energy Systems Performance Integrated with Multiple Thermal Energy Storages

    Science.gov (United States)

    Rezaie, Behnaz

    The goal of this study is to examine various energy resources in district energy (DE) systems and then DE system performance development by means of multiple thermal energy storages (TES) application. This study sheds light on areas not yet investigated precisely in detail. Throughout the research, major components of the heat plant, energy suppliers of the DE systems, and TES characteristics are separately examined; integration of various configurations of the multiple TESs in the DE system is then analysed. In the first part of the study, various sources of energy are compared, in a consistent manner, financially and environmentally. The TES performance is then assessed from various aspects. Then, TES(s) and DE systems with several sources of energy are integrated, and are investigated as a heat process centre. The most efficient configurations of the multiple TESs integrated with the DE system are investigated. Some of the findings of this study are applied on an actual DE system. The outcomes of this study provide insight for researchers and engineers who work in this field, as well as policy makers and project managers who are decision-makers. The accomplishments of the study are original developments TESs and DE systems. As an original development the Enviro-Economic Function, to balance the economic and environmental aspects of energy resources technologies in DE systems, is developed; various configurations of multiple TESs, including series, parallel, and general grid, are developed. The developed related functions are discharge temperature and energy of the TES, and energy and exergy efficiencies of the TES. The TES charging and discharging behavior of TES instantaneously is also investigated to obtain the charging temperature, the maximum charging temperature, the charging energy flow, maximum heat flow capacity, the discharging temperature, the minimum charging temperature, the discharging energy flow, the maximum heat flow capacity, and performance

  6. Novel Topic Authorship Attribution

    Science.gov (United States)

    2011-03-01

    cross-validation, genre shift, vector projection, singular value decomposition, principal component analysis Unclassified Unclassified Unclassified...by eight students. Each student wrote a total of 24 documents in three different genres about three different topics. They found that compensating for...Baayen, H. Halteren, A. Neijt, and F. Tweedie, “Outside the cave of shadows: Using syntactic annotation to enhance authorship attribution,” Literary

  7. Assessment of thermal environment landscape over five megacities in China based on Landsat 8

    Science.gov (United States)

    Meng, Dan; Yang, Siyao; Gong, Huili; Li, Xiaojuan; Zhang, Jing

    2016-04-01

    The urban thermal environment is an important element for the urban ecological environment and climate. As megacities are affected by severe thermal environment, this paper selected Landsat 8 to retrieve land surface temperature (LST) studying the thermal environment of five megacities in China including Beijing, Shanghai, Guangzhou, Tianjin, and Chengdu. Three methods have been applied, quantifying the surface urban heat island intensity, landscape pattern metrics, and spatial autocorrelation. Three main conclusions have been drawn as follows. First, high-LST area is located in the central urban area. Second, the medium-temperature region is the most prevalent. The class-based and the landscape-based metrics can detect the pattern of thermal landscape. The fragmentation is low both in low and high temperature level classes. Third, global Moran's I suggests there is spatial clustering of thermal landscape. Local Moran's I map was able to detect several high-high and low-low clusters, which are the main types of thermal landscape.

  8. The perceived temperature - a versatile index for the assessment of the human thermal environment. Part A: scientific basics

    Science.gov (United States)

    Staiger, Henning; Laschewski, Gudrun; Grätz, Angelika

    2012-01-01

    The Perceived Temperature (PT) is an equivalent temperature based on a complete heat budget model of the human body. It has proved its suitability for numerous applications across a wide variety of scales from micro to global and is successfully used both in daily forecasts and climatological studies. PT is designed for staying outdoors and is defined as the air temperature of a reference environment in which the thermal perception would be the same as in the actual environment. The calculation is performed for a reference subject with an internal heat production of 135 W m-2 (who is walking at 4 km h-1 on flat ground). In the reference environment, the mean radiant temperature equals the air temperature and wind velocity is reduced to a slight draught. The water vapour pressure remains unchanged. Under warm/humid conditions, however, it is implicitly related to a relative humidity of 50%. Clothing is adapted in order to achieve thermal comfort. If this is impossible, cold or heat stress will occur, respectively. The assessment of thermal perception by means of PT is based on Fanger's Predicted Mean Vote (PMV) together with additional model extensions taking account of stronger deviations from thermal neutrality. This is performed using a parameterisation based on a two-node model. In the cold, it allows the mean skin temperature to drop below the comfort value. In the heat, it assesses additionally the enthalpy of sweat-moistened skin and of wet clothes. PT has the advantages of being self-explanatory due to its deviation from air temperature and being—via PMV—directly linked to a thermo-physiologically-based scale of thermal perception that is widely used and has stood the test of time. This paper explains in detail the basic equations of the human heat budget and the coefficients of the parameterisations.

  9. Estimating thermal regimes of bull trout and assessing the potential effects of climate warming on critical habitats

    Science.gov (United States)

    Jones, Leslie A.; Muhlfeld, Clint C.; Marshall, Lucy A.; McGlynn, Brian L.; Kershner, Jeffrey L.

    2013-01-01

    Understanding the vulnerability of aquatic species and habitats under climate change is critical for conservation and management of freshwater systems. Climate warming is predicted to increase water temperatures in freshwater ecosystems worldwide, yet few studies have developed spatially explicit modelling tools for understanding the potential impacts. We parameterized a nonspatial model, a spatial flow-routed model, and a spatial hierarchical model to predict August stream temperatures (22-m resolution) throughout the Flathead River Basin, USA and Canada. Model comparisons showed that the spatial models performed significantly better than the nonspatial model, explaining the spatial autocorrelation found between sites. The spatial hierarchical model explained 82% of the variation in summer mean (August) stream temperatures and was used to estimate thermal regimes for threatened bull trout (Salvelinus confluentus) habitats, one of the most thermally sensitive coldwater species in western North America. The model estimated summer thermal regimes of spawning and rearing habitats at <13 C° and foraging, migrating, and overwintering habitats at <14 C°. To illustrate the useful application of such a model, we simulated climate warming scenarios to quantify potential loss of critical habitats under forecasted climatic conditions. As air and water temperatures continue to increase, our model simulations show that lower portions of the Flathead River Basin drainage (foraging, migrating, and overwintering habitat) may become thermally unsuitable and headwater streams (spawning and rearing) may become isolated because of increasing thermal fragmentation during summer. Model results can be used to focus conservation and management efforts on populations of concern, by identifying critical habitats and assessing thermal changes at a local scale.

  10. Assessment of thermal load on transported goats administered with ascorbic acid during the hot-dry conditions.

    Science.gov (United States)

    Minka, N S; Ayo, J O

    2012-03-01

    The major factor in the induction of physiological stress during road transportation of livestock is the complex fluctuations of the thermal transport microenvironment, encountered when animals are transported across different ecological zones. Recommended guidelines on optimum "on-board" conditions in which goats should be transported are lacking, and there are no acceptable ranges and limits for the thermal loads to which goats may be subjected during long-distance road transportation in hot-dry conditions. Panting score (PS), rectal temperature (RT), heart rate (HR) and respiratory rate (RR) were employed as reliable stress indices to assess the effects of different thermal loads, measured as temperature humidity index (THI), encountered in the vehicle during 12 h of road transportation of 40 goats, and to suggest the administration of 100 mg/kg body weight of ascorbic acid (AA) as an ameliorating agent. The results obtained showed that the PS, RT, HR and RR rose above normal reference values with increase in the THI and journey duration. The rise in PS value, which is a visual indicator of the severity of thermal load, was the most pronounced. The results suggest that values of THI in the vehicle up to 94.6 constitute no risk, while at of 100 it presents a moderate risk and above 100 may result in severe stress. The relationships between the thermal load and the physiological variables were positive and significant (P < 0.05). They reflect the degree of stress imposed by each THI value during the transportation, and may be used as recommended ranges and limit thermal load values in transported goats. The results demonstrated that administration of 100 mg/kg body weight of AA before road transportation mitigated the risk of adverse effects of high THI values and other stress factors due to road transportation in goats.

  11. Assessment of thermal load on transported goats administered with ascorbic acid during the hot-dry conditions

    Science.gov (United States)

    Minka, N. S.; Ayo, J. O.

    2012-03-01

    The major factor in the induction of physiological stress during road transportation of livestock is the complex fluctuations of the thermal transport microenvironment, encountered when animals are transported across different ecological zones. Recommended guidelines on optimum "on-board" conditions in which goats should be transported are lacking, and there are no acceptable ranges and limits for the thermal loads to which goats may be subjected during long-distance road transportation in hot-dry conditions. Panting score (PS), rectal temperature (RT), heart rate (HR) and respiratory rate (RR) were employed as reliable stress indices to assess the effects of different thermal loads, measured as temperature humidity index (THI), encountered in the vehicle during 12 h of road transportation of 40 goats, and to suggest the administration of 100 mg/kg body weight of ascorbic acid (AA) as an ameliorating agent. The results obtained showed that the PS, RT, HR and RR rose above normal reference values with increase in the THI and journey duration. The rise in PS value, which is a visual indicator of the severity of thermal load, was the most pronounced. The results suggest that values of THI in the vehicle up to 94.6 constitute no risk, while at of 100 it presents a moderate risk and above 100 may result in severe stress. The relationships between the thermal load and the physiological variables were positive and significant ( P < 0.05). They reflect the degree of stress imposed by each THI value during the transportation, and may be used as recommended ranges and limit thermal load values in transported goats. The results demonstrated that administration of 100 mg/kg body weight of AA before road transportation mitigated the risk of adverse effects of high THI values and other stress factors due to road transportation in goats.

  12. Summary report on UO2 thermal conductivity model refinement and assessment studies

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Xiang-Yang [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cooper, Michael William Donald [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mcclellan, Kenneth James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lashley, Jason Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Byler, Darrin David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bell, B. D.C. [Imperial College, London (United Kingdom); Grimes, R. W. [Imperial College, London (United Kingdom); Stanek, Christopher Richard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Andersson, David Ragnar [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-03

    Uranium dioxide (UO2) is the most commonly used fuel in light water nuclear reactors and thermal conductivity controls the removal of heat produced by fission, therefore, governing fuel temperature during normal and accident conditions. The use of fuel performance codes by the industry to predict operational behavior is widespread. A primary source of uncertainty in these codes is thermal conductivity, and optimized fuel utilization may be possible if existing empirical models were replaced with models that incorporate explicit thermal conductivity degradation mechanisms during fuel burn-up. This approach is able to represent the degradation of thermal conductivity due to each individual defect type, rather than the overall burn-up measure typically used which is not an accurate representation of the chemical or microstructure state of the fuel that actually governs thermal conductivity and other properties. To generate a mechanistic thermal conductivity model, molecular dynamics (MD) simulations of UO2 thermal conductivity including representative uranium and oxygen defects and fission products are carried out. These calculations employ a standard Buckingham type interatomic potential and a potential that combines the many-body embedded atom method potential with Morse-Buckingham pair potentials. Potential parameters for UO2+x and ZrO2 are developed for the latter potential. Physical insights from the resonant phonon-spin scattering mechanism due to spins on the magnetic uranium ions have been introduced into the treatment of the MD results, with the corresponding relaxation time derived from existing experimental data. High defect scattering is predicted for Xe atoms compared to that of La and Zr ions. Uranium defects reduce the thermal conductivity more than oxygen defects. For each defect and fission product, scattering parameters are derived for application in both a Callaway model and the corresponding high

  13. A comparative assessment of independent thermal-hydraulic models for research reactors: The RSG-GAS case

    Energy Technology Data Exchange (ETDEWEB)

    Chatzidakis, S., E-mail: schatzid@purdue.edu [Purdue University, School of Nuclear Engineering, West Lafayette, IN 47907 (United States); Hainoun, A. [Atomic Energy Commission of Syria (AECS), Nuclear Engineering Department, P.O. Box 6091, Damascus (Syrian Arab Republic); Doval, A. [Nuclear Engineering Department, Av. Cmdt. Luis Piedrabuena 4950, C.P. 8400, San Carlos de Bariloche, Rio Negro (Argentina); Alhabet, F. [Atomic Energy Commission of Syria (AECS), Nuclear Engineering Department, P.O. Box 6091, Damascus (Syrian Arab Republic); Francioni, F. [Nuclear Engineering Department, Av. Cmdt. Luis Piedrabuena 4950, C.P. 8400, San Carlos de Bariloche, Rio Negro (Argentina); Ikonomopoulos, A. [Institute of Nuclear and Radiological Sciences, Energy, Technology and Safety, National Center for Scientific Research ‘Demokritos’, 15130, Aghia Paraskevi, Athens (Greece); Ridikas, D. [Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna International Centre, A-1400 Vienna (Austria)

    2014-03-15

    Highlights: • Increased use of thermal-hydraulic codes requires assessment of important phenomena in RRs. • Three independent modeling teams performed analysis of loss of flow transient. • Purpose of this work is to examine the thermal-hydraulic codes response. • To perform benchmark analysis comparing the different codes with experimental measurements. • To identify the impact of the user effect on the computed results, performed with the same codes. - Abstract: This study presents the comparative assessment of three thermal-hydraulic codes employed to model the Indonesian research reactor (RSG-GAS) and simulate the reactor behavior under steady state and loss of flow transient (LOFT). The RELAP5/MOD3, MERSAT and PARET-ANL thermal-hydraulic codes are used by independent research groups to perform benchmark analysis against measurements of coolant and clad temperatures, conducted on an instrumented fuel element inside RSG-GAS core. The results obtained confirm the applicability of RELAP5/MOD3, MERSAT and PARET-ANL on the modeling of loss of flow transient in research reactors. In particular, the three codes are able to simulate flow reversal from downward forced to upward natural convection after pump trip and successful reactor scram. The benchmark results show that the codes predict maximum clad temperature of hot channel conservatively with a maximum overestimation of 27% for RELAP5/MOD3, 17% for MERSAT and 8% for PARET-ANL. As an additional effort, the impact of user effect on the simulation results has been assessed for the code RELAP5/MOD3, where the main differences among the models are presented and discussed.

  14. Development and evaluation of colloidal modified nanolipid carrier: application to topical delivery of tacrolimus, Part II--in vivo assessment, drug targeting, efficacy, and safety in treatment for atopic dermatitis.

    Science.gov (United States)

    Pople, Pallavi V; Singh, Kamalinder K

    2013-05-01

    In atopic dermatitis (AD), topical anti-inflammatory therapy with skin barrier restoration to prevent repeated inflammatory episodes leads to long-term therapeutic success. Tacrolimus, although effective against AD, is a challenging molecule due to low solubility, low-penetration, poor-bioavailability, and toxicity. Part I of this paper, reported novel modified nanolipid carrier system for topical delivery of tacrolimus (T-MNLC), offering great opportunity to load low-solubility drug with improved entrapment efficiency, enhanced stability and improved skin deposition. Present investigation focused on restoration of skin barrier, site-specific delivery, therapeutic effectiveness, and safety of novel T-MNLC. T-MNLC greatly enhanced occlusive properties, skin hydration potential and reduced transepidermal water loss. This might help to reduce the number of flares and better control the disease. Cutaneous uptake and drug deposition in albino rats by HPLC and confocal laser scanning microscopy revealed prominently elevated drug levels in all skin strata with T-MNLC as compared to reference. T-MNLC demonstrated efficient suppression of inflammatory responses in BALB/c mice model of AD. Safety assessment by acute and repeated-dose dermal toxicity demonstrated mild keratosis and collagenous mass infiltration at the treatment area with repeated application of reference. Interestingly, T-MNLC showed no evident toxicity exhibiting safe drug delivery. Thus, novel T-MNLC would be a safe, effective, and esthetically appealing alternative to conventional vehicles for treatment for AD.

  15. A research needs assessment for the capture, utilization and disposal of carbon dioxide from fossil fuel-fired power plants. Volume 2, Topical reports: Final report

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    This study, identifies and assesses system approaches in order to prioritize research needs for the capture and non-atmospheric sequestering of a significant portion of the carbon dioxide (CO{sub 2}) emitted from fossil fuel-fired electric power plants (US power plants presently produce about 7% of the world`s CO{sub 2} emissions). The study considers capture technologies applicable either to existing plants or to those that optimistically might be demonstrated on a commercial scale over the next twenty years. The research needs that have high priority in establishing the technical, environmental, and economic feasibility of large-scale capture and disposal of CO{sub 2} from electric power plants are:(1) survey and assess the capacity, cost, and location of potential depleted gas and oil wells that are suitable CO{sub 2} repositories (with the cooperation of the oil and gas industry); (2) conduct research on the feasibility of ocean disposal, with objectives of determining the cost, residence time, and environmental effects for different methods of CO{sub 2} injection; (3) perform an in-depth survey of knowledge concerning the feasibility of using deep, confined aquifers for disposal and, if feasible, identify potential disposal locations (with the cooperation of the oil and gas industry); (4) evaluate, on a common basis, system and design alternatives for integration of CO{sub 2} capture systems with emerging and advanced technologies for power generation; and prepare a conceptual design, an analysis of barrier issues, and a preliminary cost estimate for pipeline networks necessary to transport a significant portion of the CO{sub 2} to potentially feasible disposal locations.

  16. Neutron transport simulation (selected topics)

    Science.gov (United States)

    Vaz, P.

    2009-10-01

    Neutron transport simulation is usually performed for criticality, power distribution, activation, scattering, dosimetry and shielding problems, among others. During the last fifteen years, innovative technological applications have been proposed (Accelerator Driven Systems, Energy Amplifiers, Spallation Neutron Sources, etc.), involving the utilization of intermediate energies (hundreds of MeV) and high-intensity (tens of mA) proton accelerators impinging in targets of high Z elements. Additionally, the use of protons, neutrons and light ions for medical applications (hadrontherapy) impose requirements on neutron dosimetry-related quantities (such as kerma factors) for biologically relevant materials, in the energy range starting at several tens of MeV. Shielding and activation related problems associated to the operation of high-energy proton accelerators, emerging space-related applications and aircrew dosimetry-related topics are also fields of intense activity requiring as accurate as possible medium- and high-energy neutron (and other hadrons) transport simulation. These applications impose specific requirements on cross-section data for structural materials, targets, actinides and biologically relevant materials. Emerging nuclear energy systems and next generation nuclear reactors also impose requirements on accurate neutron transport calculations and on cross-section data needs for structural materials, coolants and nuclear fuel materials, aiming at improved safety and detailed thermal-hydraulics and radiation damage studies. In this review paper, the state-of-the-art in the computational tools and methodologies available to perform neutron transport simulation is presented. Proton- and neutron-induced cross-section data needs and requirements are discussed. Hot topics are pinpointed, prospective views are provided and future trends identified.

  17. Neutron transport simulation (selected topics)

    Energy Technology Data Exchange (ETDEWEB)

    Vaz, P. [Instituto Tecnologico e Nuclear, Estrada Nacional 10, P-2686-953 Sacavem (Portugal)], E-mail: pedrovaz@itn.pt

    2009-10-15

    Neutron transport simulation is usually performed for criticality, power distribution, activation, scattering, dosimetry and shielding problems, among others. During the last fifteen years, innovative technological applications have been proposed (Accelerator Driven Systems, Energy Amplifiers, Spallation Neutron Sources, etc.), involving the utilization of intermediate energies (hundreds of MeV) and high-intensity (tens of mA) proton accelerators impinging in targets of high Z elements. Additionally, the use of protons, neutrons and light ions for medical applications (hadrontherapy) impose requirements on neutron dosimetry-related quantities (such as kerma factors) for biologically relevant materials, in the energy range starting at several tens of MeV. Shielding and activation related problems associated to the operation of high-energy proton accelerators, emerging space-related applications and aircrew dosimetry-related topics are also fields of intense activity requiring as accurate as possible medium- and high-energy neutron (and other hadrons) transport simulation. These applications impose specific requirements on cross-section data for structural materials, targets, actinides and biologically relevant materials. Emerging nuclear energy systems and next generation nuclear reactors also impose requirements on accurate neutron transport calculations and on cross-section data needs for structural materials, coolants and nuclear fuel materials, aiming at improved safety and detailed thermal-hydraulics and radiation damage studies. In this review paper, the state-of-the-art in the computational tools and methodologies available to perform neutron transport simulation is presented. Proton- and neutron-induced cross-section data needs and requirements are discussed. Hot topics are pinpointed, prospective views are provided and future trends identified.

  18. Application of remote sensing to thermal pollution analysis. [satellite sea surface temperature measurement assessment

    Science.gov (United States)

    Hiser, H. W.; Lee, S. S.; Veziroglu, T. N.; Sengupta, S.

    1975-01-01

    A comprehensive numerical model development program for near-field thermal plume discharge and far field general circulation in coastal regions is being carried on at the University of Miami Clean Energy Research Institute. The objective of the program is to develop a generalized, three-dimensional, predictive model for thermal pollution studies. Two regions of specific application of the model are the power plants sites at the Biscayne Bay and Hutchinson Island area along the Florida coastline. Remote sensing from aircraft as well as satellites are used in parallel with in situ measurements to provide information needed for the development and verification of the mathematical model. This paper describes the efforts that have been made to identify problems and limitations of the presently available satellite data and to develop methods for enhancing and enlarging thermal infrared displays for mesoscale sea surface temperature measurements.

  19. Analytical assessment of the thermal behavior of nickel-metal hydride batteries during fast charging

    Science.gov (United States)

    Taheri, Peyman; Yazdanpour, Maryam; Bahrami, Majid

    2014-01-01

    A novel distributed transient thermal model is proposed to investigate the thermal behavior of nickel-metal hydride (NiMH) batteries under fast-charging processes at constant currents. Based on the method of integral transformation, a series-form solution for the temperature field inside the battery core is obtained that takes account for orthotropic heat conduction, transient heat generation, and convective heat dissipation at surfaces of the battery. The accuracy of the developed theoretical model is confirmed through comparisons with numerical and experimental data for a sample 30 ampere-hour NiMH battery. The comparisons show that even the first term of the series solution fairly predicts the temperature field with the modest numerical cost. The thermal model is also employed to define an efficiency for charging processes. Our calculations confirm that the charging efficiency decreases as the charging current increases.

  20. Topics in Operator Theory

    CERN Document Server

    Ball, Joseph A; Helton, JWilliam; Rodman, Leiba; Spitkovsky, Iiya

    2010-01-01

    This is the first volume of a collection of original and review articles on recent advances and new directions in a multifaceted and interconnected area of mathematics and its applications. It encompasses many topics in theoretical developments in operator theory and its diverse applications in applied mathematics, physics, engineering, and other disciplines. The purpose is to bring in one volume many important original results of cutting edge research as well as authoritative review of recent achievements, challenges, and future directions in the area of operator theory and its applications.

  1. Topics in field theory

    CERN Document Server

    Karpilovsky, G

    1989-01-01

    This monograph gives a systematic account of certain important topics pertaining to field theory, including the central ideas, basic results and fundamental methods.Avoiding excessive technical detail, the book is intended for the student who has completed the equivalent of a standard first-year graduate algebra course. Thus it is assumed that the reader is familiar with basic ring-theoretic and group-theoretic concepts. A chapter on algebraic preliminaries is included, as well as a fairly large bibliography of works which are either directly relevant to the text or offer supplementary material of interest.

  2. Topical cidofovir for plantar warts.

    Science.gov (United States)

    Padilla España, Laura; Del Boz, Javier; Fernández Morano, Teresa; Arenas Villafranca, Javier; de Troya Martín, Magdalena

    2014-01-01

    Plantar warts are a common reason for dermatological consultations and their treatment can occasionally be a challenge. Plantar warts are benign lesions produced by the human papillomavirus (HPV) that often fail to respond to habitual treatment. Cidofovir is a potent antiviral drug that acts competitively, inhibiting viral DNA polymerase. Our aim was to assess the efficacy and safety of cidofovir cream for the treatment of viral plantar warts. We undertook a retrospective observational study of patients with plantar warts who received treatment with topical cidofovir between July 2008 and July 2011 at the Dermatology Service of the Hospital Costa del Sol, Marbella, Spain. Data about the rate of treatment response, the adverse effects, and recurrences, as well as the characteristics of the patient cohort, were recorded. We identified 35 patients who had received some previous treatment. The usual concentration was 3% (in 33 of 35 cases), applied twice a day (in 31 of 35 cases). A greater or lesser response was noted in 28 cases. There were two recurrences. Topical cidofovir seems to be a useful alternative for the therapeutic management of recalcitrant plantar common warts that fail to respond to usual treatment.

  3. Thermal energy storage technologies for sustainability systems design, assessment and applications

    CERN Document Server

    Kalaiselvam, S

    2014-01-01

    Thermal Energy Storage Technologies for Sustainability is a broad-based overview describing the state-of-the-art in latent, sensible, and thermo-chemical energy storage systems and their applications across industries. Beginning with a discussion of the efficiency and conservation advantages of balancing energy demand with production, the book goes on to describe current state-of-the art technologies. Not stopping with description, the authors also discuss design, modeling, and simulation of representative systems, and end with several case studies of systems in use.Describes how thermal energ

  4. Assessment of thermal comfort level at pedestrian level in high-density urban area of Hong Kong

    Science.gov (United States)

    Ma, J.; Ng, E.; Yuan, C.; Lai, A.

    2015-12-01

    Hong Kong is a subtropical city which is very hot and humid in the summer. Pedestrians commonly experience thermal discomfort. Various studies have shown that the tall bulky buildings intensify the urban heat island effect and reduce urban air ventilation. However, relatively few studies have focused on modeling the thermal load at pedestrian level (~ 2 m). This study assesses the thermal comfort level, quantified by PET (Physiological Equivalent Temperature), using a GIS - based simulation approach. A thermal comfort level map shows the PET value of a typical summer afternoon in the high building density area. For example, the averaged PET in Sheung Wan is about 41 degree Celsius in a clear day and 38 degree Celsius in a cloudy day. This map shows where the walkways, colonnades, and greening is most needed. In addition, given a start point, a end point, and weather data, we generate the most comfort walking routes weighted by the PET. In the simulation, shortwave irradiance is calculated using the topographic radiation model (Fu and Rich, 1999) under various cloud cover scenarios; longwave irradiance is calculated based the radiative transfer equation (Swinbank, 1963). Combining these two factors, Tmrt (mean radiant temperature) is solved. And in some cases, the Tmrt differ more than 40 degree Celsius between areas under the sun and under the shades. Considering thermal load and wind information, we found that shading from buildings has stronger effect on PET than poor air ventilation resulted from dense buildings. We predict that pedestrians would feel more comfortable (lower PET) in a hot summer afternoon when walking in the higher building density area.

  5. Assessment of industry views on international business prospects for solar thermal technology

    Energy Technology Data Exchange (ETDEWEB)

    Easterling, J.C.

    1984-09-01

    This report contains a review of solar thermal industry viewpoints on their prospects for developing international business. The report documents the industry's current involvement in foreign markets, view of foreign competition in overseas applications, and view of federal R and D and policy requirements to strengthen international business prospects. The report is based on discussions with equipment manufacturers and system integrators who have a product or service with potential international demand. Interviews with manufacturers and system integrators were conducted by using a standard format for interview questions. The use of a standard format for questions provided a basis for aggregating similar views expressed by US companies concerning overseas business prospects. A special effort was made to gather responses from the entire solar thermal industry, including manufacturers of line-focus, point-focus, and central receiver systems. General, technical, economic, institutional, and financial findings are provided in this summary. In addition, Pacific Northwest Laboratory (PNL) recommendations are provided (based upon advice from the Solar Thermal Review Panel) for activities to improve US solar thermal business prospects overseas.

  6. Regional assessment of aquifers for thermal-energy storage. Volume 2. Regions 7 through 12

    Energy Technology Data Exchange (ETDEWEB)

    1981-06-01

    This volume contains information on the geologic and hydrologic framework, major aquifers, aquifers which are suitable and unsuitable for annual thermal energy storage (ATES) and the ATES potential of the following regions of the US: Unglaciated Central Region; Glaciated Appalachians, Unglaciated Appalachians; Coastal Plain; Hawaii; and Alaska. (LCL)

  7. Regional assessment of aquifers for thermal energy storage. Volume 1. Regions 1 through 6

    Energy Technology Data Exchange (ETDEWEB)

    1981-06-01

    This volume contains information on the geologic and hydrologic framework, major aquifers, aquifers which are suitable and unsuitable for annual thermal energy storage (ATES) and the ATES potential of the following regions of the US: the Western Mountains; Alluvial Basins; Columbia LAVA Plateau; Colorado Plateau; High Plains; and Glaciated Central Region. (LCL)

  8. Theoretical assessment of electro-thermal imaging: A new technique for medical diagnosis

    Science.gov (United States)

    Carlak, H. Feza; Gencer, Nevzat G.; Besikci, Cengiz

    2016-05-01

    Breast cancer is one of the most crucial cancer types. To improve the diagnosis performance, a hybrid system is proposed through simultaneous utilization of thermal and electrical impedance imaging methods. The innovation of the approach relies on the frequency dependence of the tissue's electrical impedance which facilitates the acquisition of multiple thermal images with currents at different frequencies injected to the region of the body under inspection. The applied current and the resulting heating at the body surface are distributed based on the frequency dependent conductivity distribution. The electrical currents increase the thermal contrast on the body surface depending on the electrical properties of the tissues at the operation frequency. The technique also provides frequency dependent conductivity distribution data through thermal imaging which can be used as a basis for the detection of the breast carcinoma. Based on our findings, the contrast resolution between the healthy and cancerous tissue is increased, improving the depth-dependent imaging performance from 3 mm to 9 mm for a 1.5 mm tumor. The sensitivity of the technique can be further increased by an infrared camera with dual band imaging capability. Consequently, the proposed approach has a potential to improve the sensitivity and accuracy of medical imaging over the standard thermography.

  9. Photopyroelectric assessment of the thermal effusivity of fresh hen egg and of rehydrated egg powders

    NARCIS (Netherlands)

    Szafner, G.; Nemeth, C.; Bicanic, D.D.; Doka, O.

    2015-01-01

    The availability of thermo-physical data of foods and their constituents is of general importance to food industry. The thermal effusivity e is one among the relevant thermodynamical quantities. The latter is normally calculated from the relationship e = (¿¿c)½, where c is specific heat, ¿ is the de

  10. PA Discussion Topics

    Science.gov (United States)

    2011-02-04

    lower priority discussion ADD-TARDEC Network Centric Military Energy Control (NCMEC) Future discussion ADD-TARDEC M&S for Hybrid Electric Vehicles ...Approved for public release • OBJECTIVES: Reduce Thermal Burden on Vehicles Reduce Converter Operating Power • APPROACH: Develop compact...APU) that delivers 5 kWe (Threshold), 10 kWe (Objective) of vehicle electrical power demonstrated at TRL 5. • System designed to fit into an

  11. Hot topics for leadership development.

    Science.gov (United States)

    Bleich, Michael R

    2015-02-01

    Three areas stand out from a health systems perspective that should be on the development agenda for all leaders. These topics include population health, predictive analytics, and supply chain management. Together, these topics address access, quality, and cost management.

  12. Feasibility and validity of animal-based indicators for on-farm welfare assessment of thermal stress in dairy goats

    Science.gov (United States)

    Battini, Monica; Barbieri, Sara; Fioni, Luna; Mattiello, Silvana

    2016-02-01

    This investigation tested the feasibility and validity of indicators of cold and heat stress in dairy goats for on-farm welfare assessment protocols. The study was performed on two intensive dairy farms in Italy. Two different 3-point scale (0-2) scoring systems were applied to assess cold and heat stress. Cold and heat stress scores were visually assessed from outside the pen in the morning, afternoon and evening in January-February, April-May and July 2013 for a total of nine sessions of observations/farm. Temperature (°C), relative humidity (%) and wind speed (km/h) were recorded and Thermal Heat Index (THI) was calculated. The sessions were allocated to three climatic seasons, depending on THI ranges: cold (65). Score 2 was rarely assessed; therefore, scores 1 and 2 were aggregated for statistical analysis. The amount of goats suffering from cold stress was significantly higher in the cold season than in neutral ( P < 0.01) and hot ( P < 0.001) seasons. Signs of heat stress were recorded only in the hot season ( P < 0.001). The visual assessment from outside the pen confirms the on-farm feasibility of both indicators: No constraint was found and time required was less than 10 min. Our results show that cold and heat stress scores are valid indicators to detect thermal stress in intensively managed dairy goats. The use of a binary scoring system (presence/absence), merging scores 1 and 2, may be a further refinement to improve the feasibility. This study also allows the prediction of optimal ranges of THI for dairy goat breeds in intensive husbandry systems, setting a comfort zone included into 55 and 70.

  13. Seasonal thermal energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Allen, R.D.; Kannberg, L.D.; Raymond, J.R.

    1984-05-01

    This report describes the following: (1) the US Department of Energy Seasonal Thermal Energy Storage Program, (2) aquifer thermal energy storage technology, (3) alternative STES technology, (4) foreign studies in seasonal thermal energy storage, and (5) economic assessment.

  14. Topics in orbit equivalence

    CERN Document Server

    Kechris, Alexander S

    2004-01-01

    This volume provides a self-contained introduction to some topics in orbit equivalence theory, a branch of ergodic theory. The first two chapters focus on hyperfiniteness and amenability. Included here are proofs of Dye's theorem that probability measure-preserving, ergodic actions of the integers are orbit equivalent and of the theorem of Connes-Feldman-Weiss identifying amenability and hyperfiniteness for non-singular equivalence relations. The presentation here is often influenced by descriptive set theory, and Borel and generic analogs of various results are discussed. The final chapter is a detailed account of Gaboriau's recent results on the theory of costs for equivalence relations and groups and its applications to proving rigidity theorems for actions of free groups.

  15. Topics in atomic physics

    CERN Document Server

    Burkhardt, Charles E

    2006-01-01

    The study of atomic physics propelled us into the quantum age in the early twentieth century and carried us into the twenty-first century with a wealth of new and, in some cases, unexplained phenomena. Topics in Atomic Physics provides a foundation for students to begin research in modern atomic physics. It can also serve as a reference because it contains material that is not easily located in other sources. A distinguishing feature is the thorough exposition of the quantum mechanical hydrogen atom using both the traditional formulation and an alternative treatment not usually found in textbooks. The alternative treatment exploits the preeminent nature of the pure Coulomb potential and places the Lenz vector operator on an equal footing with other operators corresponding to classically conserved quantities. A number of difficult to find proofs and derivations are included as is development of operator formalism that permits facile solution of the Stark effect in hydrogen. Discussion of the classical hydrogen...

  16. Environmental assessment of the potential effects of aquifer thermal energy storage systems on microorganisms in groundwater

    Energy Technology Data Exchange (ETDEWEB)

    Hicks, R.J.; Stewart, D.L.

    1988-03-01

    The primary objective of this study was to evaluate the potential environmental effects (both adverse and beneficials) of aquifer thermal energy storage (ATES) technology pertaining to microbial communities indigenous to subsurface environments (i.e., aquifers) and the propagation, movement, and potential release of pathogenic microorganisms (specifically, Legionella) within ATES systems. Seasonal storage of thermal energy in aquifers shows great promise to reduce peak demand; reduce electric utility load problems; contribute to establishing favorable economics for district heating and cooling systems; and reduce pollution from extraction, refining, and combustion of fossil fuels. However, concerns that the widespread implementation of this technology may have adverse effects on biological systems indigeneous to aquifers, as well as help to propagate and release pathogenic organisms that enter thee environments need to be resolved. 101 refs., 2 tabs.

  17. Thermal performances and melting risk assessment in a LMFBR fuel pin

    Science.gov (United States)

    Vettraino, F.; Cacciabue, P. C.; Brunelli, F.

    1985-02-01

    A reliable evaluation of fuel temperature is a key safety requirement in the design of the fuel assembly of a nuclear reactor, especially in the case of a LMFBR whose efficient operation requires high thermal performance fuel. The physico-chemical properties such as density, oxygen to metal ratio and thermal conductivity of a typical LMFBR mixed-oxide fuel, which are known to change in a remarkable way under irradiation, strongly affect the temperature profile within the fuel pellet. A statistical analysis of the temperature values in the fuel of the Italian Fast Reactor PEC, has been performed by means of the RSM code (Response Surface Methodology) coupled to a Monte-Carlo Technique (MUP code), in order to demonstrate that the melting risk is substantially negligible.

  18. A model of human physiology and comfort for assessing complex thermal environments

    Energy Technology Data Exchange (ETDEWEB)

    Huizenga, C.; Zhang Hui; Arens, E. [University of California, Berkeley, CA (United States). Center for Environmental Design Research

    2001-07-01

    The Berkeley Comfort Model is based on the Stolwijk model of human thermal regulation but includes several significant improvements. Our new model allows an unlimited body segment (compared to six in the Stolwijk model). Each segment is modeled as four body layers (core, muscle, fat, and skin tissues) and a clothing layer. Physiological mechanisms such as vasodilation, vasoconstriction, sweating, and metabolic heat production are explicitly considered. Convection, conduction (such as to a car seat or other surface in contact with any part of the body) and radiation between the body and the environment are treated independently. The model is capable of predicting human physiological response to transient, non-uniform thermal environments. This paper describes the physiological algorithms as well as the implementation of the model. (author)

  19. Assessment of the technoeconomic feasibility or seasonal thermal energy storage systems (STES)

    Energy Technology Data Exchange (ETDEWEB)

    1978-12-01

    The feasibility of the use of Seasonal Thermal Energy Storage (STES) systems employing large volumes of water is examined on the bases of technology and economics. Three building types are considered: single-family houses, low-rise multi-family apartment buildings, and small commercial buildings. Construction costs are based on prevailing conditions in the suburban Chicago area marketplace. Various types of vessels above and below ground are considered along with possible vessel materials. (MHR)

  20. Neutron Tomography Using Mobile Neutron Generators for Assessment of Void Distributions in Thermal Hydraulic Test Loops

    OpenAIRE

    Andersson, Peter; Bjelkenstedt, Tom; Andersson Sundén, Erik; Sjöstrand, Henrik; Jacobsson, Staffan

    2015-01-01

    Detailed knowledge of the lateral distribution of steam (void) and water in a nuclear fuel assembly is of great value for nuclear reactor operators and fuel manufacturers, with consequences for both reactor safety and economy of operation. Therefore, nuclear relevant two-phase flows are being studied at dedicated thermal-hydraulic test loop, using twophase flow systems ranging from simplified geometries such as heated circular pipes to full scale mock-ups of nuclear fuel assemblies. Neutron t...

  1. Assessment of two thermally treated drill mud wastes for landfill containment applications.

    Science.gov (United States)

    Carignan, Marie-Pierre; Lake, Craig B; Menzies, Todd

    2007-10-01

    Offshore oil and gas drilling operations generate significant amounts of drill mud waste, some of which is transported onshore for subsequent thermal treatment (i.e. via thermal remediation). This treatment process results in a mineral waste by-product (referred to as thermally treated drill mud waste; TTDMW). Bentonites are originally present in many of the drill mud products and it is hypothesized that TTDMW can be utilized in landfill containment applications (i.e. cover or base liner). The objective of this paper is to examine the feasibility of this application by performing various physical and chemical tests on two TTDMW samples. It is shown that the two TTDMW samples contained relatively small amounts of clay-sized minerals although hydraulic conductivity values are found to be less than 10(-8) m/s. Organic carbon contents of the samples were approximately 2%. Mineralogy characterization of the samples confirmed varying amounts of smectite, however, peak friction angles for a TTDMW sample was greater than 36 degrees. Chemical characterization of the TTDMW samples show potential leaching of barium and small amounts of other heavy metals. Discussion is provided in the paper on suggestions to assist in overcoming regulatory issues associated with utilization of TTDMW in landfill containment applications.

  2. Thermal property and assessment of biocompatibility of poly(lactic-co-glycolic) acid/graphene nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Adhikari, Ananta R., E-mail: aa8381@gmail.com [Texas Center for Superconductivity, University of Houston, Houston, Texas-77204 (United States); Rusakova, Irene; Chu, Wei-Kan [Texas Center for Superconductivity, University of Houston, Houston, Texas-77204 (United States); Department of Physics, University of Houston, Texas-77204 (United States); Haleh, Ardebili [Department of Mechanical Engineering, University of Houston, Texas, Texas-77204 (United States); Luisi, Jonathan; Panova, Neli I.; Laezza, Fernanda [Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas-77555 (United States)

    2014-02-07

    Polymer-matrix nanocomposites based on Poly(lactic-co-glycolic) acid (PLGA) and Graphene platelets (GNPs) were studied. GNPs, nanomaterials with a 2D flat surface, were chosen with or without chemical modification in PLGA/GNP nanocomposites and their microstructure, thermal property, and their compatibility as scaffolds for cell growth were investigated. PLGA/GNP nanocomposites (0, 1, and 5 wt. % of GNPs) were prepared using a solution based technique. Transmission electron microscopy, X-ray diffraction, Differential scanning calorimeter, and Thermogravimetric analyzer were used to analyze morphology and thermal properties. This work demonstrated the role of GNPs flat surface to provide a favorable platform resulting in an enhanced PLGA crystallization. Functionalized GNPs suppress both the thermal stability and the crystallization of PLGA. Finally, to determine the potential usefulness of these scaffolds for biomedical applications, mammalian cells were cultured on various PLGA/GNP nanocomposites (0, 1, and 5 wt. % GNPs). 1 wt. % PLGA/GNP nanocomposites showed better biocompatibility for cell growth with/without graphenes functionalization compared to pure PLGA and 5 wt. % PLGA/GNP. The function of GNPs in PLGA/GNPs (1 wt. %) composites is to provide a stage for PLGA crystallization where cell growth is favored. These results provide strong evidence for a new class of materials that could be important for biomedical applications.

  3. An assessment of the CORCON-MOD3 code. Part 1: Thermal-hydraulic calculations

    Energy Technology Data Exchange (ETDEWEB)

    Strizhov, V.; Kanukova, V.; Vinogradova, T.; Askenov, E. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Safety; Nikulshin, V. [Russian Research Center, Moscow (Russian Federation). Kurchatov Inst.

    1996-09-01

    This report deals with the subject of CORCON-Mod3 code validation (thermal-hydraulic modeling capability only) based on MCCI (molten core concrete interaction) experiments conducted under different programs in the past decade. Thermal-hydraulic calculations (i.e., concrete ablation, melt temperature, melt energy, concrete temperature, and condensible and non-condensible gas generation) were performed with the code, and compared with the data from 15 experiments, conducted at different scales using both simulant (metallic and oxidic) and prototypic melt materials, using different concrete types, and with and without an overlying water pool. Sensitivity studies were performed in a few cases involving, for example, heat transfer from melt to concrete, condensed phase chemistry, etc. Further, special analysis was performed using the ACE L8 experimental data to illustrate the differences between the experimental and the reactor conditions, and to demonstrate that with proper corrections made to the code, the calculated results were in better agreement with the experimental data. Generally, in the case of dry cavity and metallic melts, CORCON-Mod3 thermal-hydraulic calculations were in good agreement with the test data. For oxidic melts in a dry cavity, uncertainties in heat transfer models played an important role for two melt configurations--a stratified geometry with segregated metal and oxide layers, and a heterogeneous mixture. Some discrepancies in the gas release data were noted in a few cases.

  4. Assessment the Synoptic Variability of Vertical Thermal Structure in Baltic Sea Waters on the Base of in-situ Measurements

    Science.gov (United States)

    Koch, A.; Klevantsov, J.; Rozhkov, V.

    2004-12-01

    The thermal regime of sea's active layer is determined by its interaction with atmosphere, thermal balance, wind and convective water mixing. The question about assessment of synoptic variability of thermal stratification in Baltic Sea waters has not yet solved. The purpose of the present work was to determine the bounds of synoptic variability of vertical temperature profiles T(z) at the all seasons on the example of Bornholm Basin in the Baltic Sea. On the base of the large array of episodic measurements at the international stations BY, situated in key regions of the Baltic Sea, the principles of annual rhythmic of vertical distribution of water temperature are given in the paper [1]. However, this data does not allow separate the synoptic variability from seasonal and inter-annual diapasons, since measurements at fixed horizon belong to different synoptic events at different years. During 1978-1988 the State Oceanographic Institute (Leningrad/Saint-Petersburg Branch) on the base of Russian RV "Rudolf Samoylovich" was carrying out observations of hydrological and hydro-chemical elements of Baltic Sea waters at the stations BY [2]. The originality of carried out work is that for the first time continuous series of measurements for elements of vertical thermo-haline structure with duration from day to several months and discreteness of 3 hour were executed. These observations got name "Multi-daily Stations". This data alongside with the data of episodic observations allows separate synoptic variability of water temperature profile and assess its degree. Vertical thermal structure of sea waters has been typified based on the parameters of profile geometry. The degree of synoptic variability in each element of profile T(z) for all the seasons has determined. It has been showed, that the enthalpy is the optimal thermal regime parameter for separating the synoptic diapason from others. It has also been showed, that synoptic variability of water temperature in deep

  5. Life cycle assessment of hemp cultivation and use of hemp-based thermal insulator materials in buildings.

    Science.gov (United States)

    Zampori, Luca; Dotelli, Giovanni; Vernelli, Valeria

    2013-07-02

    The aim of this research is to assess the sustainability of a natural fiber, such as hemp (Cannabis sativa), and its use as thermal insulator for building applications. The sustainability of hemp was quantified by life cycle assessment (LCA) and particular attention was given to the amount of CO2eq of the whole process, and the indicator greenhouse gas protocol (GGP) was selected to quantify CO2eq emissions. In this study also CO2 uptake of hemp was considered. Two different allocation procedures (i.e., mass and economic) were adopted. Other indicators, such as Cumulative Energy Demand (CED) and EcoIndicator99 H were calculated. The production of 1 ha yielded 15 ton of hemp, whose global warming potential (GWP100) was equal to about -26.01 ton CO2eq: the amount allocated to the technical fiber (20% of the total amount of hemp biomass) was -5.52 ton CO2eq when mass allocation was used, and -5.54 ton CO2eq when economic allocation was applied. The sustainability for building applications was quantified by considering an insulation panel made by hemp fiber (85%) and polyester fiber (15%) in 1 m(2) of wall having a thermal transmittance (U) equal to 0.2 W/m(2)_K. The environmental performances of the hemp-based panel were compared to those of a rockwool-based one.

  6. A novel methodology of internal assessment of uncertainty for three-dimensional neutronics/thermal-hydraulics system codes

    Energy Technology Data Exchange (ETDEWEB)

    Petruzzi, A.; Auria, F. [Pisa Universita, Dipartimento di Ingegneria Meccanica, Nucleare e della Produzione, Pisa (Italy); Ivanov, K. [Pennsylvania State University, Department of Mechanical and Nuclear Engineering, PA (Italy)

    2003-07-01

    The paper stresses how the internal assessment of uncertainty is a desirable capability for thermal-hydraulic system codes. This consists of the possibility of obtaining proper uncertainty bands each time a nuclear plant transient scenario is calculated. A methodology suitable for introducing such a capability into a system code is discussed. At the basis of the derivation of the code with (the capability of) internal assessment of uncertainty (CIAU), there is the uncertainty methodology based on the accuracy extrapolation (UMAE), previously proposed by the University of Pisa, although other uncertainty methodologies can be used for the same purpose. The idea of the CIAU is the identification and the characterization of standard plant statuses and the association of uncertainty to each status. One hypercube and one time interval identify the plant status. Quantity and time uncertainties are combined for each plant status. The RELAP5/MOD3.2 system code has been used inside the CIAU to show the applicability of the proposed method. The derivation of the methodology is discussed, and reference results of pressurized water reactor plant transients are shown bounded by the CIAU calculated uncertainty bands. Recently, a new activity has been started with the aim to extend the CIAU to the 3D neutronics/thermal-hydraulics coupled codes. (authors)

  7. Assessment of the efficacy of a topical combination of fipronil-permethrin (Frontline Tri-Act®/Frontect® against egg laying and adult emergence of the cat flea (Ctenocephalides felis in dogs

    Directory of Open Access Journals (Sweden)

    Beugnet Frédéric

    2016-01-01

    Full Text Available This study was conducted to assess the prevention of egg laying and the inhibition of the emergence of the cat flea (Ctenocephalides felis resulting from the application of a combination of fipronil and permethrin (Frontline Tri-Act®/Frontect®, Merial on dogs. Sixteen healthy dogs were included after pre-treatment live flea counts and randomly allocated to two groups. Eight dogs served as untreated controls and 8 dogs were treated on Day 0 and Day 30 with topical application of fipronil/permethrin at the minimum dose of 6.76 mg/kg fipronil and 50.48 mg/kg permethrin. On days −2, 7, 21, 28, 42 and 56, each dog was infested with 100 fleas. Flea eggs were collected from each dog in individual trays from 12 to 36 h after treatment or each flea re-infestation. All fleas were removed by combing and counted 36 h after treatment or infestations. The collected eggs were counted and incubated for 28 days for larval development and adult emergence assessment. The curative efficacy of Frontline Tri-Act®/Frontect® against adult fleas 36 h after treatment was 95.3% and the efficacy remained 100% after subsequent flea infestations for 8 weeks. Compared to the control group, the treatment reduced egg laying by 84.5% within 36 h after first treatment and was 99.9%, 100%, 100%, 100%, 100% on collection days 7, 21, 29, 43 and 57, respectively. Frontline Tri-Act®/Frontect® reduced by 28.7% the emergence of new adult fleas from eggs laid during the 48 h of pre-treatment infestation. The inhibition of adult emergence from incubated flea eggs could not be assessed after flea re-infestation in the treated group as no eggs were collected.

  8. Assessment of thermal performance for the design of a passively-cooled plutonium storage vault

    Science.gov (United States)

    Sanders, Joseph Conway

    A passively-cooled plutonium storage vault, rather than one with a safety-qualified, forced-flow cooling system, could save as much as 100 million over the project lifetime. Either configuration must maintain the temperature of the stored plutonium metal, with its significant internal heat generation, below 239 sp circF. Alpha-phase metal, if allowed to exceed this temperature, will transition to beta-phase metal and undergo a volumetric expansion which could rupture the storage container system. An investigation was performed to determine whether a passively-cooled vault is feasible. Significant temperature drops occurred in two regions, both were gas-filled vertical annuli with heat flux boundary conditions on the inner surfaces and fixed temperature boundary conditions on the outer surfaces. The thermal resistance method was employed to evaluate radial heat transfer across each annulus, coupling natural convection, radiation, and conduction. Correlations from Thomas et al and Kulacki et al were used to evaluate the degree of natural convective enhancement. For the helium-filled region between the plutonium metal rod and the container with a characteristic length of 3.9 centimeters and an aspect ratio of 5.6, the Rayleigh number was 800 when the effect of radiation was removed. This resulted in a Nusselt number of 1.8. For the air-filled region between twelve vertically arranged containers and the storage tube with a characteristic length of 5.8 centimeters and an aspect ratio of 78, the Rayleigh number was 5times10sp5. This resulted in a Nusselt number of approximately 4.5, neglecting the effect of radiation. FIDAP 7.62\\copyright$ (Fluid Dynamics Analysis Package) was used to perform multi-dimensional finite element analyses of these regions employing both buoyant and radiative effects. Both simplified and more geometrically complex models were employed, all of which compared favorably to the results using the thermal resistance method. The results of the

  9. Advanced verification topics

    CERN Document Server

    Bhattacharya, Bishnupriya; Hall, Gary; Heaton, Nick; Kashai, Yaron; Khan Neyaz; Kirshenbaum, Zeev; Shneydor, Efrat

    2011-01-01

    The Accellera Universal Verification Methodology (UVM) standard is architected to scale, but verification is growing and in more than just the digital design dimension. It is growing in the SoC dimension to include low-power and mixed-signal and the system integration dimension to include multi-language support and acceleration. These items and others all contribute to the quality of the SOC so the Metric-Driven Verification (MDV) methodology is needed to unify it all into a coherent verification plan. This book is for verification engineers and managers familiar with the UVM and the benefits it brings to digital verification but who also need to tackle specialized tasks. It is also written for the SoC project manager that is tasked with building an efficient worldwide team. While the task continues to become more complex, Advanced Verification Topics describes methodologies outside of the Accellera UVM standard, but that build on it, to provide a way for SoC teams to stay productive and profitable.

  10. Topics in statistical mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Elser, V.

    1984-05-01

    This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references.

  11. Superconcentration and related topics

    CERN Document Server

    Chatterjee, Sourav

    2014-01-01

    A certain curious feature of random objects, introduced by the author as “super concentration,” and two related topics, “chaos” and “multiple valleys,” are highlighted in this book. Although super concentration has established itself as a recognized feature in a number of areas of probability theory in the last twenty years (under a variety of names), the author was the first to discover and explore its connections with chaos and multiple valleys. He achieves a substantial degree of simplification and clarity in the presentation of these findings by using the spectral approach. Understanding the fluctuations of random objects is one of the major goals of probability theory and a whole subfield of probability and analysis, called concentration of measure, is devoted to understanding these fluctuations. This subfield offers a range of tools for computing upper bounds on the orders of fluctuations of very complicated random variables. Usually, concentration of measure is useful when more direct prob...

  12. Researching Distressing Topics

    Directory of Open Access Journals (Sweden)

    Sharon Jackson

    2013-05-01

    Full Text Available Qualitative researchers who explore sensitive topics may expose themselves to emotional distress. Consequently, researchers are often faced with the challenge of maintaining emotional equilibrium during the research process. However, discussion on the management of difficult emotions has occupied a peripheral place within accounts of research practice. With rare exceptions, the focus of published accounts is concentrated on the analysis of the emotional phenomena that emerge during the collection of primary research data. Hence, there is a comparative absence of a dialogue around the emotional dimensions of working with secondary data sources. This article highlights some of the complex ways in which emotions enter the research process during secondary analysis, and the ways in which we engaged with and managed emotional states such as anger, sadness, and horror. The concepts of emotional labor and emotional reflexivity are used to consider the ways in which we “worked with” and “worked on” emotion. In doing so, we draw on our collective experiences of working on two collaborative projects with ChildLine Scotland in which a secondary analysis was conducted on children’s narratives of distress, worry, abuse, and neglect.

  13. Assessment of structural, thermal, and mechanical properties of portlandite through molecular dynamics simulations

    Science.gov (United States)

    Hajilar, Shahin; Shafei, Behrouz

    2016-12-01

    The structural, thermal, and mechanical properties of portlandite, the primary solid phase of ordinary hydrated cement paste, are investigated using the molecular dynamics method. To understand the effects of temperature on the structural properties of portlandite, the coefficients of thermal expansion of portlandite are determined in the current study and validated with what reported from the experimental tests. The atomic structure of portlandite equilibrated at various temperatures is then subjected to uniaxial tensile strains in the three orthogonal directions and the stress-strain curves are developed. Based on the obtained results, the effect of the direction of straining on the mechanical properties of portlandite is investigated in detail. Structural damage analysis is performed to reveal the failure mechanisms in different directions. The energies of the fractured surfaces are calculated in different directions and compared to those of the ideal surfaces available in the literature. The key mechanical properties, including tensile strength, Young's modulus, and fracture strain, are extracted from the stress-strain curves. The sensitivity of the obtained mechanical properties to temperature and strain rate is then explored in a systematic way. This leads to valuable information on how the structural and mechanical properties of portlandite are affected under various exposure conditions and loading rates.

  14. IR thermography for the assessment of the thermal conductivity of thermoelectric modules at intermediate temperature

    Science.gov (United States)

    Boldrini, S.; Ferrario, A.; Bison, P.; Miozzo, A.; Montagner, F.; Fabrizio, M.

    2016-05-01

    The correct measurement of the performances of thermoelectric (TE) modules for energy conversion is a mandatory task both for laboratory research and for industries engaged in TE modules development or in their integration into thermoelectric generators. A testing device oriented to the maximum flexibility, based on the heat flow meter method at the cold side of the module has been developed. The system is conceived to test TE modules (single or in cascade) with a footprint up to 60x60 mm2, from room temperature up to intermediate temperature. Modules can be tested under vacuum or inert atmosphere. Specifically, the flow meter is made of a block of material, with known thermal conductivity, in contact with the cold side of the thermoelectric module. The heat flow is finally determined by measuring the temperature profile along the heat flow path and that is obtained by IR thermography. IR thermography is also utilized to evaluate the contact resistance between the active thermoelectric elements made of ceramic materials and the ceramic layer working as heat diffuser and mechanical support. Some finite element thermal analyses of the system performed for its design are presented.

  15. Assessment of increased thermal activity at Mount Baker, Washington, March 1975-March 1976

    Science.gov (United States)

    Frank, David; Meier, Mark Frederick; Swanson, Donald A.; with contributions by Babcock, James W.; Fretwell, Marvin O.; Malone, Stephen D.; Rosenfeld, Charles L.; Shreve, Ronald L.; Wilcox, Ray E.

    1977-01-01

    In March 1975 Mount Baker showed a large increase in thermal emission, which has persisted for more than 1 year. Fumarole ejecta accompanied the thermal activity from March to September, but the ejecta had no constituents that suggest a magmatic source. Estimates of that part of the total heat flux that would account for the observed snow and ice loss show that the heat-flow increase was roughly one order of magnitude, from about 2 megawatts at 10 watts per square meter, averaged over Sherman Crater before 1975, to about 30 megawatts at 180 watts per square meter, during 1975. Almost half of the glacier that occupied the basin of Sherman Crater was melted in 1975. The new activity generated great concern among the public and the government agencies responsible for geological evaluation of potential hazards and for protection of life and property. The past geologic history, current topography, rock alteration, and location of major fumarolic activity indicate that large rock avalanches and mudflows on the east slope in Boulder Creek valley are the potential hazards of most significance related to present conditions. The most probable types of large mass movements would be mudflows, having speeds of as much as 50 kilometers per hour, that would originate from mixtures of snow, ice, and melt water and avalanches of structurally weak clay-rich rocks that make up the rim of Sherman Crater. Similar mudflows from the volcano have traveled at least 12 kilometers 8 times during the past 10,000 years. A possible worst case event, however, might be a larger, air-cushioned avalanche of as much as 20 to 30 million cubic meters that could hit Baker Lake at speeds of more than 300 kilometers per hour and generate a wave of water large enough to overtop Upper Baker Dam. At least 30 million cubic meters of potentially unstable material occurs as hydrothermally altered remnants of the rim of Sherman Crater and could provide the required volume for the estimated worst case event or

  16. Discovering health topics in social media using topic models.

    Directory of Open Access Journals (Sweden)

    Michael J Paul

    Full Text Available By aggregating self-reported health statuses across millions of users, we seek to characterize the variety of health information discussed in Twitter. We describe a topic modeling framework for discovering health topics in Twitter, a social media website. This is an exploratory approach with the goal of understanding what health topics are commonly discussed in social media. This paper describes in detail a statistical topic model created for this purpose, the Ailment Topic Aspect Model (ATAM, as well as our system for filtering general Twitter data based on health keywords and supervised classification. We show how ATAM and other topic models can automatically infer health topics in 144 million Twitter messages from 2011 to 2013. ATAM discovered 13 coherent clusters of Twitter messages, some of which correlate with seasonal influenza (r = 0.689 and allergies (r = 0.810 temporal surveillance data, as well as exercise (r =  .534 and obesity (r =  -.631 related geographic survey data in the United States. These results demonstrate that it is possible to automatically discover topics that attain statistically significant correlations with ground truth data, despite using minimal human supervision and no historical data to train the model, in contrast to prior work. Additionally, these results demonstrate that a single general-purpose model can identify many different health topics in social media.

  17. KEY TOPICS IN SPORTS MEDICINE

    Directory of Open Access Journals (Sweden)

    Amir Ali Narvani

    2006-12-01

    Full Text Available Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1 Sports injuries, rehabilitation and injury prevention, 2 Exercise physiology, fitness testing and training, 3 Drugs in sport, 4 Exercise and health promotion, 5 Sport and exercise for special and clinical populations, 6 The psychology of performance and injury. PURPOSE The Key Topics format provides extensive, concise information in an accessible, easy-to-follow manner. AUDIENCE The book is targeted the students and specialists in sports medicine and rehabilitation, athletic training, physiotherapy and orthopaedic surgery. The editors are authorities in their respective fields and this handbook depends on their extensive experience and knowledge accumulated over the years. FEATURES The book contains the information for clinical guidance, rapid access to concise details and facts. It is composed of 99 topics which present the information in an order that is considered logical and progressive as in most texts. Chapter headings are: 1. Functional Anatomy, 2. Training Principles / Development of Strength and Power, 3. Biomechanical Principles, 4. Biomechanical Analysis, 5. Physiology of Training, 6. Monitoring of Training Progress, 7. Nutrition, 8. Hot and Cold Climates, 9. Altitude, 10. Sport and Travelling, 11. Principles of Sport Injury Diagnosis, 12. Principles of Sport and Soft Tissue Management, 13. Principles of Physical Therapy and Rehabilitation, 14. Principles of Sport Injury Prevention, 15. Sports Psychology, 16. Team Sports, 17. Psychological Aspects of Injury in Sport, 18. Injury Repair Process, 19. Basic Biomechanics of Tissue Injury, 20. Plain Film Radiography in Sport, 21. Nuclear Medicine, 22. Diagnostic Ultrasound, 23. MRI Scan, 24. Other Imaging, 5. Head Injury, 26. Eye

  18. An Assessment of Testing Requirement Impacts on Nuclear Thermal Propulsion Ground Test Facility Design

    Science.gov (United States)

    Shipers, Larry R.; Ottinger, Cathy A.; Sanchez, Lawrence C.

    1994-07-01

    Programs to develop solid core nuclear thermal propulsion (NTP) systems have been under way at the Department of Defense (DoD), the National Aeronautics and Space Administration (NASA), and the Department of Energy (DOE). These programs have recognized the need for a new ground test facility to support development of NTP systems. However, the different military and civilian applications have led to different ground test facility requirements. The Department of Energy (DOE) in its role as landlord and operator of the proposed research reactor test facilities has initiated an effort to explore opportunities for a common ground test facility to meet both DoD and NASA needs. The baseline design and operating limits of the proposed DoD NTP ground test facility are described. The NASA ground test facility requirements are reviewed and their potential impact on the DoD facility baseline is discussed.

  19. An assessment of testing requirement impacts on nuclear thermal propulsion ground test facility design

    Energy Technology Data Exchange (ETDEWEB)

    Shipers, L.R.; Ottinger, C.A.; Sanchez, L.C.

    1993-10-25

    Programs to develop solid core nuclear thermal propulsion (NTP) systems have been under way at the Department of Defense (DoD), the National Aeronautics and Space Administration (NASA), and the Department of Energy (DOE). These programs have recognized the need for a new ground test facility to support development of NTP systems. However, the different military and civilian applications have led to different ground test facility requirements. The Department of Energy (DOE) in its role as landlord and operator of the proposed research reactor test facilities has initiated an effort to explore opportunities for a common ground test facility to meet both DoD and NASA needs. The baseline design and operating limits of the proposed DoD NTP ground test facility are described. The NASA ground test facility requirements are reviewed and their potential impact on the DoD facility baseline is discussed.

  20. Assessment of thermal change in cold avalanching glaciers in relation to climate warming

    Science.gov (United States)

    Gilbert, A.; Vincent, C.; Gagliardini, O.; Krug, J.; Berthier, E.

    2015-08-01

    High-elevation glaciers covered by cold firn are undergoing substantial warming in response to ongoing climate change. This warming is affecting the ice/rock interface temperature, the primary driver of avalanching glacier instability on steep slopes. Prediction of future potential instability therefore requires appropriate modeling of the thermal evolution of these glaciers. Application of a state-of-the-art model to a glacier in the French Alps (Taconnaz) has provided the first evaluation of the temperature evolution of a cold hanging glacier through this century. Our observations and three-dimensional modeling of the glacier response (velocity, thickness, temperature, density, and water content) to climate change indicate that Taconnaz glacier will become temperate and potentially unstable over a large area by the end of the 21st century. The risk induced by this glacier hazard is high for the populated region below and makes observation and modeling of such glaciers a priority.

  1. 转基因水稻食用安全性评价内容与主要争论问题分析%Assessment of Food Safety and Analysis of Main Debated Topics in Transgenic Rice

    Institute of Scientific and Technical Information of China (English)

    肖国樱; 陈芬; 孟秋成; 周浩

    2012-01-01

    The policy of food safety assessment of transgenic rice in China was introduced, and the contents and standards of food safety assessment, including toxicological assessment of foreign protein, allergen assessment of foreign protein, assessment of major nutrient composition and anti-nutritional factors in GMO products, content assessment of foreign proteins in GMO products, thermal stability and digestibility of foreign proteins, and food safety assessment for whole GMO products, were related based on an example of transgenic rice. The analysis was conducted on the debated questions such as whether it is safe for a human being to eat transgenic rice or to eat it for a long time since stem borers will die from eating it, whether there is a logical mistake in substantial equivalence principle for transgenic products, or whether the substantial equivalence principle is only beneficial to multinational corporations. The prospect of the transgenic rice in China was outlined that it would need a gradual accumulation in early stages and then it would have a rapid growth and an extensive application in commercial production.%介绍了中国转基因水稻食用安全性评价的政策依据,并以实例为基础介绍了食用安全性评价的主要内容、检测标准:新表达物质毒理学评价、新表达物质致敏性评价、关键营养成份与抗营养因子检测、新表达物质含量(表达量)检测、新表达物质热稳定性和可消化性检测、全食品安全性检测等.针对转基因水稻螟虫不能吃,人是否能吃,是否能长期吃,实质等同性原则是否存在逻辑错误、偏袒大公司等问题进行了分析.对中国转基因水稻的发展前景进行了评论,认为前期需要有一个渐进、积累的过程,但之后将快速覆盖、急剧增长.

  2. Development of creep damage assessment system for aged thermal power plant

    Energy Technology Data Exchange (ETDEWEB)

    Nonaka, Isamu [IshikawaJima-Harima Heavy Industries Co., Ltd., Tokyo (Japan); Umaki, Hideo [Ishikawajima-Harima Heavy Industries Co., Ltd., Tokyo (Japan); Nishida, Hidetalca [The Chugoku Electric Power Co., Inc., Hiroshima (Japan); Yamaguchi, Hiroshi [The Chugoku Electric Power Co., Inc., Hiroshima (Japan)

    1998-12-31

    IHI has developed the Creep Damage Assessment System to identify voids by processing an image observed by a small laser microscope with an advanced image processing technique jointly with Chugoku Electric Power Co., Inc. The result can be obtained immediately on the spot. Application tests of the system at the Unit No.3 boiler of the Kudamatsu Power Station showed good operability, adaptability to the environment, and accuracy. The new system can easily indicate damage conditions in parts during the periodical inspection, allowing rapid maintenance. Time reduction required for assessment and increased reliability of equipment can be also achieved. (orig.)

  3. Design analysis and risk assessment for a single stage to orbit nuclear thermal rocket

    Science.gov (United States)

    Labib, Satira I.

    Recent advances in high power density fuel materials have renewed interest in nuclear thermal rockets (NTRs) as a viable propulsion technology for future space exploration. This thesis describes the design of three NTR reactor engines designed for the single stage to orbit launch of payloads from 1-15 metric tons. Thermal hydraulic and rocket engine analyses indicate that the proposed rocket engines are able to reach specific impulses in excess of 700 seconds. Neutronics analyses performed using MCNP5 demonstrate that the hot excess reactivity, shutdown margin, and submersion criticality requirements are satisfied for each NTR reactor. The reactors each consist of a 40 cm diameter core packed with hexagonal tungsten cermet fuel elements. The core is surrounded by radial and axial beryllium reflectors and eight boron carbide control drums. At the same power level, the 40 cm reactor results in the lowest radiation dose rate of the three reactors. Radiation dose rates decrease to background levels ~3.5 km from the launch site. After a one-year decay time, all of the activated materials produced by an NTR launch would be classified as Class A low-level waste. The activation of air produces significant amounts of argon-41 and nitrogen-16 within 100 m of the launch. The derived air concentration, DAC, from the activation products decays to less than unity within two days, with only argon-41 remaining. After 10 minutes of full power operation the 120 cm core corresponding to a 15 MT payload contains 2.5 x 1013, 1.4 x 1012, 1.5 x 1012, and 7.8 x 10 7 Bq of 131I, 137Cs, 90Sr, and 239Pu respectively. The decay heat after shutdown increases with increasing reactor power with a maximum decay heat of 108 kW immediately after shutdown for the 15 MT payload.

  4. Does the Core Contain Potassium?: An Assessment of the Uncertainties in Thermal and Dynamo Evolution Models

    Science.gov (United States)

    Nimmo, F.

    2006-12-01

    The long-term thermal evolution of the core, and the history of the geodynamo, are determined by the rate at which heat is extracted from the core, and the presence of any heat sources within the core [1,2]. Radioactive potassium may provide one such heat source: mineral physics results [3,4] are permissive but not definitive; cosmochemical constraints are weak [5]; and geoneutrino detection [6] does not yet have the required resolution. Theoretical models [1-2,7-9] can help to address whether or not potassium is present in the core. Since the evolution of the CMB heat flux is hard to calculate, a better approach is to assume that the entropy available to power the geodynamo has remained constant over time, and to infer the resulting heat flux [2]. Unfortunately, several important parameters, notably core thermal conductivity and the entropy production rate required to sustain the geodynamo, are uncertain. I have carried out a suite of models using a wide range of parameter values based on published results. In the absence of potassium, an ancient inner core [10] and a continuously active geodynamo are only possible if 1) the dissipation generated by the dynamo is small, Gessmann and Wood, EPSL 200, 63-78, 2002. [5] Lassiter G3, Q11012, 2004. [6] Araki et al., Nature 436, 499-503, 2005. [7] Lister PEPI 140, 145-158, 2003. [8] Roberts et al., in Earth's Core and Lower Mantle, ed. Jones et al. [9] Nimmo et al. GJI 156, 363-376, 2004. [10] Brandon et al., EPSL 206, 411-426, 2003. [11] Hernlund et al., Nature 434, 882-886, 2005. [12] Zhong, JGR 111, B04409, 2006.

  5. Assessment of thermal effects of interstitial laser phototherapy on mammary tumors using proton resonance frequency method

    Science.gov (United States)

    Le, Kelvin; Li, Xiaosong; Figueroa, Daniel; Towner, Rheal A.; Garteiser, Philippe; Saunders, Debra; Smith, Nataliya; Liu, Hong; Hode, Tomas; Nordquist, Robert E.; Chen, Wei R.

    2011-12-01

    Laser immunotherapy (LIT) uses a synergistic approach to treat cancer systemically through local laser irradiation and immunological stimulation. Currently, LIT utilizes dye-assisted noninvasive laser irradiation to achieve selective photothermal interaction. However, LIT faces difficulties treating deeper tumors or tumors with heavily pigmented overlying skin. To circumvent these barriers, we use interstitial laser irradiation to induce the desired photothermal effects. The purpose of this study is to analyze the thermal effects of interstitial irradiation using proton resonance frequency (PRF). An 805-nm near-infrared laser with an interstitial cylindrical diffuser was used to treat rat mammary tumors. Different power settings (1.0, 1.25, and 1.5 W) were applied with an irradiation duration of 10 min. The temperature distributions of the treated tumors were measured by a 7 T magnetic resonance imager using PRF. We found that temperature distributions in tissue depended on both laser power and time settings, and that variance in tissue composition has a major influence in temperature elevation. The temperature elevations measured during interstitial laser irradiation by PRF and thermocouple were consistent, with some variations due to tissue composition and the positioning of the thermocouple's needle probes. Our results indicated that, for a tissue irradiation of 10 min, the elevation of rat tumor temperature ranged from 8 to 11°C for 1 W and 8 to 15°C for 1.5 W. This is the first time a 7 T magnetic resonance imager has been used to monitor interstitial laser irradiation via PRF. Our work provides a basic understanding of the photothermal interaction needed to control the thermal damage inside a tumor using interstitial laser treatment. Our work may lead to an optimal protocol for future cancer treatment using interstitial phototherapy in conjunction with immunotherapy.

  6. Thermal analysis on parchments I: DSC and TGA combined approach for heat damage assessment

    DEFF Research Database (Denmark)

    Fessas, D.; Signorelli, M.; Schiraldi, A.;

    2006-01-01

    Ancient, new and artificially aged parchments were investigated with both differential scanning calorimetry (DSC) and thermogravimetry (TGA). Criteria to define a quantitative ranking of the damage experienced by the bulk collagen of historical parchments were assessed. A damage-related correlati...

  7. Reproducibility of axon reflex-related vasodilation assessed by dynamic thermal imaging in healthy subjects

    NARCIS (Netherlands)

    M.D. Nieuwenhoff (Mariska D.); Y. Wu; F.J.P.M. Huygen (Frank); A.C. Schouten (A.); F.C.T. van der Helm (Frans); S.P. Niehof (Sjoerd)

    2016-01-01

    textabstractIntroduction Small nerve fiber dysfunction is an early feature of diabetic neuropathy. There is a strong clinical need for a non-invasive method to assess small nerve fiber function. Small nerve fibers mediate axon reflex-related vasodilation and play an important role in thermoregulati

  8. Reproducibility of axon reflex-related vasodilation assessed by dynamic thermal imaging in healthy subjects

    NARCIS (Netherlands)

    M.D. Nieuwenhoff (Mariska D.); Wu, Y.; F.J.P.M. Huygen (Frank); A.C. Schouten (A.); F.C.T. van der Helm (Frans C.); S.P. Niehof (Sjoerd)

    2016-01-01

    textabstractIntroduction: Small nerve fiber dysfunction is an early feature of diabetic neuropathy. There is a strong clinical need for a non-invasive method to assess small nerve fiber function. Small nerve fibers mediate axon reflex-related vasodilation and play an important role in thermoregulati

  9. Assessment of thermal shock induced damage in silicon carbide fibre reinforced glass matrix composites

    Directory of Open Access Journals (Sweden)

    Boccaccini, A. R.

    1998-09-01

    Full Text Available The development of microstructural damage in silicon carbide fibre (Nicalon™ reinforced glass matrix composite samples subjected to thermal shock was investigated by using a nondestructive forced resonance technique and fibre push out indentation tests. Thermal shock testing involved quenching samples in a water bath maintained at room temperature from a high temperature (650ºC. Changes in the Young's modulus and internal friction of the samples with increasing number of shocks were measured accurately by the forced resonance technique. Fibre push-out tests showed no significant changes in the properties of the fibre-matrix interface, indicating that damage in the composite was concentrated mainly in the development of matrix microcracking. It was also shown that the internal friction is a very sensitive parameter by which to detect the onset and development of such microcracking. A simple semi-empirical model is proposed to correlate the internal friction level with the microcracking density in the glass matrix. Finally, the relevance of detecting nondestructively the existence of microcracks in the glass matrix, before any significant interfacial degradation occurs, is emphasized, in conextion with the possibility of inducing a crack healing process by a thermal treatment (annealing, taking advantage of the viscous flow properties of the glass.

    El desarrollo de daño microestructural en materiales compuestos de matriz de vidrio reforzados con fibras de carburo de silicio (Nicalon™ sometidos a choque térmico fue investigado mediante la técnica no-destructiva de resonancia forzada y por mediciones de indentación "push-out" de fibras. Los ensayos de choque térmico involucraron el enfriamiento brusco en un baño de agua a temperatura ambiente de las piezas previamente calentadas a una temperatura elevada (650ºC. La técnica de resonancia forzada permitió medir cambios en el módulo de Young de elasticidad y en la fricci

  10. Part A: Assessing the performance of the COMFA outdoor thermal comfort model on subjects performing physical activity

    Science.gov (United States)

    Kenny, Natasha A.; Warland, Jon S.; Brown, Robert D.; Gillespie, Terry G.

    2009-09-01

    This study assessed the performance of the COMFA outdoor thermal comfort model on subjects performing moderate to vigorous physical activity. Field tests were conducted on 27 subjects performing 30 min of steady-state activity (walking, running, and cycling) in an outdoor environment. The predicted COMFA budgets were compared to the actual thermal sensation (ATS) votes provided by participants during each 5-min interval. The results revealed a normal distribution in the subjects’ ATS votes, with 82% of votes received in categories 0 (neutral) to +2 (warm). The ATS votes were significantly dependent upon sex, air temperature, short and long-wave radiation, wind speed, and metabolic activity rate. There was a significant positive correlation between the ATS and predicted budgets (Spearman’s rho = 0.574, P < 0.01). However, the predicted budgets did not display a normal distribution, and the model produced erroneous estimates of the heat and moisture exchange between the human body and the ambient environment in 6% of the cases.

  11. Post-Flight Assessment of Avcoat Thermal Protection System for the Exploration Flight Test-1

    Science.gov (United States)

    Bose, Deepak; Santos, Jose; Rodriguez, Erika; Mahzari, Milad; Remark, Brian; Muppidi, Suman

    2016-01-01

    On December 5, 2014 NASA conducted the first flight test of its next generation human-class Orion spacecraft. The flight was called the Exploration Flight Test -1 (EFT-1) which lasted for 4 hours and culminated into a re-entry trajectory at 9 km/s. This flight test of the 5-meter Orion Crew Module demonstrated various sub-systems including the Avcoat ablative thermal protection system (TPS) on the heat shield. The Avcoat TPS had been developed from the Apollo-era recipe with a few key modifications. The engineering for thermal sizing was supported by modeling, analysis, and ground tests in arc jet facilities. This paper will describe a postlfight analysis plan and present results from post-recovery inspections, data analysis from embedded sensors, TPS sample extraction and characterization in the laboratory. After the recovery of the vehicle, a full photographic survey and surface scans of the TPS were performed. The recovered vehicle showed physical evidence of flow disturbances, varying degrees of surface roughness, and excessive recession downstream of compression pads. The TPS recession was measured at more than 200 locations of interest on the Avcoat surface. The heat shield was then processed for sample extraction prior to TPS removal using the 7-Axis Milling machine at Marshall Space Flight Center. Around 182 rectangular TPS samples were extracted for subsequent analysis and investigation. The final paper will also present results of sample analysis. The planned investigation includes sidewall imaging, followed by image analysis to characterize TPS response by quantifying different layers in the char and pyrolysis zones. A full postmortem of the instrumentation and sensor ports will also be performed to confirm no adverse effects due to the sensors themselves. A subset of the samples will undergo structural testing and perform detailed characterization of any cracks and integrity of gore seams. Finally, the material will be characterized with layer

  12. Initial risk assessment for a single stage to orbit nuclear thermal rocket

    Energy Technology Data Exchange (ETDEWEB)

    Labib, Satira, E-mail: Satira.Labib@duke-energy.com; King, Jeffrey, E-mail: kingjc@mines.edu

    2015-06-15

    Highlights: • The risks posed by the surface launch of a nuclear thermal rocket are considered. • Radiation exposure at the public viewing distance is insignificant. • Production of fission products and actinides during launch is limited. • The production of activated argon around the rocket may be a significant concern. - Abstract: In order to consider the possibility of a nuclear thermal rocket (NTR) ground launch, it is necessary to evaluate the risks from such a launch. This includes analysis of the radiation dose rate around the rocket, determining the rate of activation of the materials near the launch, and considering the radionuclides present in the core after the launch. This paper evaluates the potential risk of the NTR ground launch for a range of payloads from 1 to 15 metric tons (MT) using three NTR reactor cores (40, 80, and 120 cm in length) designed in a previous study, based on data produced by MCNP5 and MCNPX models. At the same power level, the 40 cm core length reactor results in the lowest radiation dose rate of the three reactors. Radiation dose rates decrease to background levels 3.5 km from the launch site. After a 1-year decay time, all of the activated materials produced by an NTR launch would be classified as Class A low-level waste. The activation of air produces significant amounts of argon-41 and nitrogen-16 within 100 m of the launch. The derived air concentration (DAC) ratio of the activation products decays to less than unity within 2 days, with only argon-41 remaining. After 10 min of full power operation, the 120 cm core for a 15 MT payload contains 2.5 × 10{sup 13}, 1.4 × 10{sup 12} and 1.5 × 10{sup 12} Bq of {sup 131}I, {sup 137}Cs, and {sup 90}Sr, respectively. The decay heat after shutdown increases with increasing reactor power with a maximum decay heat of 108 kW immediately after shutdown for the 15 MT payload.

  13. Assessment of Thermal Dehydration Using the Human Eye: What is the Potential?

    Science.gov (United States)

    2012-01-01

    multifunctional neuroendocrine gland. Prog. Retin. Eye Res. 26, 239–262. Connors, B.W., 2009. Sensory transduction. In: Boron , W.F., Boulpaep, E.L. (Eds.), Medical ...relevant physiological basis for testing the merit of ocular measures for human hydration assessment and recent data indicate that Tosm and IOP may have...Rudolf Foundation Clinic, Vienna, Austria d Centre of Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria a r t

  14. Assessment of urban thermal stress by UTCI – experimental and modelling studies: an example from Poland

    Directory of Open Access Journals (Sweden)

    Błażejczyk, Krzysztof

    2014-09-01

    Full Text Available The paper presents a new approach to the study of the spatial variability of heat stress in urban areas. The Universal Thermal Climate Index UTCI was applied for this purpose. The spatial variability of UTCI at the local scale was studied using examples of urban areas with different sizes and geographical locations. The experimental research on urban heat stress was conducted in Warsaw. The research covers both differences between UTCI in urban to rural areas as well as the variation of heat stress within small residential districts in Warsaw. We found a very large and significant heat stress gradient between downtown Warsaw and rural stations. Spatial variability of UTCI was also observed in microclimate research. A modelling approach was presented based on examples from Warsaw, a city with a population of almost 2 million, as well as examples from several spa towns with populations of up to 40,000 located in various parts of Poland. GIS analysis (ArcGIS for Desktop and IDRISI was applied for this purpose.

  15. DECOVALEX III PROJECT. Thermal-Hydro-Mechanical Coupled Processes in Safety Assessments. Report of Task 4

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Johan [JA Streamflow AB, Aelvsjoe (Sweden)

    2005-02-15

    A part (Task 4) of the International DECOVALEX III project on coupled thermo-hydro-mechanical (T-H-M) processes focuses on T-H-M modelling applications in safety and performance assessment of deep geological nuclear waste repositories. A previous phase, DECOVALEX II, saw a need to improve such modelling. In order to address this need Task 4 of DECOVALEX III has: Analysed two major T-H-M experiments (Task 1 and Task 2) and three different Bench Mark Tests (Task 3) set-up to explore the significance of T-H-M in some potentially important safety assessment applications. Compiled and evaluated the use of T-H-M modelling in safety assessments at the time of the year 2000. Organised a forum a forum of interchange between PA-analysts and THM modelers at each DECOVALEX III workshop. Based on this information the current report discusses the findings and strives for reaching recommendations as regards good practices in addressing coupled T-H-M issues in safety assessments. The full development of T-H-M modelling is still at an early stage and it is not evident whether current codes provide the information that is required. However, although the geosphere is a system of fully coupled processes, this does not directly imply that all existing coupled mechanisms must be represented numerically. Modelling is conducted for specific purposes and the required confidence level should be considered. It is necessary to match the confidence level with the modelling objective. Coupled THM modelling has to incorporate uncertainties. These uncertainties mainly concern uncertainties in the conceptual model and uncertainty in data. Assessing data uncertainty is important when judging the need to model coupled processes. Often data uncertainty is more significant than the coupled effects. The emphasis on the need for THM modelling differs among disciplines. For geological radioactive waste disposal in crystalline and other similar hard rock formations DECOVALEX III shows it is essential to

  16. The topical treatment of psoriasis.

    NARCIS (Netherlands)

    Kerkhof, P.C.M. van de; Vissers, W.H.P.M.

    2003-01-01

    According to the patients, improvement of efficacy, long-term safety and improvement of compliance are needed. The topical treatment has been innovated during the last decade. Most important are the introduction of two new classes of treatments: topical vitamin D(3) analogues and the retinoid tazaro

  17. Topics of Evolutionary Computation 2001

    DEFF Research Database (Denmark)

    Ursem, Rasmus Kjær

    This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem......This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem...

  18. Topical Day on Biological Effects of Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Baatout, S.; Jacquet, P.

    1997-05-15

    The topical day has been focussed on the potential effects of ionizing radiation on human health. A general overview on molecular and biophysical aspects of radiation, its effects on cells and organisms, and the contribution of radiobiology to radiation protection and risk assessment is given. The genetic effects of radiation and its effects on the developing organism, the effects of radiation on the cell cycle and the mechanisms of radiation induced apoptosis were also discussed.

  19. Assessment of the PIUS physics and thermal-hydraulic experimental data bases

    Energy Technology Data Exchange (ETDEWEB)

    Boyack, B.E. [Los Alamos National Lab., NM (United States). Technology and Safety Assessment Div.

    1993-12-31

    The PIUS reactor utilizes simplified, inherent, passive, or other innovative means to accomplish safety functions. Accordingly, the PIUS reactor is subject to the requirements of 10CFR52.47(b)(2)(i)(A). This regulation requires that the applicant adequately demonstrate the performance of each safety feature, interdependent effects among the safety features, and a sufficient data base on the safety features of the design to assess the analytical tools used for safety analysis. Los Alamos has assessed the quality and completeness of the existing and planned data bases used by Asea Brown Boveri to validate its safety analysis codes and other relevant data bases. Only a limited data base of separate effect and integral tests exist at present. This data base is not adequate to fulfill the requirements of 10CFR52.47(b)(2)(i)(A). Asea Brown Boveri has stated that it plans to conduct more separate effect and integral test programs. If appropriately designed and conducted, these test programs have the potential to satisfy most of the data base requirements of 10CFR52.47(b)(2)(i)(A) and remedy most of the deficiencies of the currently existing combined data base. However, the most important physical processes in PIUS are related to reactor shutdown because the PIUS reactor does not contain rodded shutdown and control systems. For safety-related reactor shutdown, PIUS relies on negative reactivity insertions from the moderator temperature coefficient and from boron entering the core from the reactor pool. Asea Brown Boveri has neither developed a direct experimental data base for these important processes nor provided a rationale for indirect testing of these key PIUS processes. This is assessed as a significant shortcoming. In preparing the conclusions of this report, test documentation and results have been reviewed for only one integral test program, the small-scale integral tests conducted in the ATLE facility.

  20. Damodar Valley Corporation, Chandrapura Unit 2 Thermal Power Station Residual Life Assessment Summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    The BHEL/NTPC/PFC/TVA teams assembled at the DVC`s Chadrapura station on July 19, 1994, to assess the remaining life of Unit 2. The workscope was expanded to include major plant systems that impact the unit`s ability to sustain generation at 140 MW (Units 1-3 have operated at average rating of about 90 MW). Assessment was completed Aug. 19, 1994. Boiler pressure parts are in excellent condition except for damage to primary superheater header/stub tubes and economizer inlet header stub tubes. The turbine steam path is in good condition except for damage to LP blading; the spar rotor steam path is in better condition and is recommended for Unit 2. Nozzle box struts are severely cracked from the flame outs; the cracks should not be repaired. HP/IP rotor has surface cracks at several places along the steam seal areas; these cracks are shallow and should be machined out. Detailed component damage assessments for above damaged components have been done. The turbine auxiliary systems have been evaluated; cooling tower fouling/blockage is the root cause for the high turbine back pressure. The fuel processing system is one of the primary root causes for limiting unit capacity. The main steam and hot reheat piping systems were conservatively designed and have at least 30 years left;deficiencies needing resolution include restoration of insulation, replacement of 6 deformed hanger clamp/bolts, and adjustment of a few hanger settings. The cold reheat piping system is generally in good condition; some areas should be re-insulated and the rigid support clamps/bolts should be examined. The turbine extraction piping system supports all appeared to be functioning normally.

  1. Assessment of SAR and thermal changes near a cochlear implant system for mobile phone type exposures.

    Science.gov (United States)

    McIntosh, Robert L; Iskra, Steve; McKenzie, Raymond J; Chambers, John; Metzenthen, Bill; Anderson, Vitas

    2008-01-01

    A cochlear implant system is a device used to enable hearing in people with severe hearing loss and consists of an internal implant and external speech processor. This study considers the effect of scattered radiofrequency fields when these persons are subject to mobile phone type exposure. A worst-case scenario is considered where the antenna is operating at nominal full power, the speech processor is situated behind the ear using a metallic hook, and the antenna is adjacent to the hook and the internal ball electrode. The resultant energy deposition and thermal changes were determined through numerical modelling. With a 900 MHz half-wave dipole antenna producing continuous-wave (CW) 250 mW power, the maximum 10 g averaged SAR was 1.31 W/kg which occurred in the vicinity of the hook and the ball electrode. The maximum temperature increase was 0.33 degrees C in skin adjacent to the hook. For the 1800 MHz antenna, operating at 125 mW, the maximum 10 g averaged SAR was 0.93 W/kg in the pinna whilst the maximum temperature change was 0.16 degrees C. The analysis predicts that the wearer complies with the radiofrequency safety limits specified by the International Commission on Non-Ionizing Radiation Protection (ICNIRP), the Institute of Electrical and Electronics Engineers (IEEE), and the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) for 900 and 1800 MHz mobile phone type exposure and thus raises no cause for concern. The resultant temperature increase is well below the maximum rise of 1 degrees C recommended by ICNIRP. Effects in the cochlea were insignificant.

  2. Assessment and Correction of on-Orbit Radiometric Calibration for FY-3 VIRR Thermal Infrared Channels

    Directory of Open Access Journals (Sweden)

    Na Xu

    2014-03-01

    Full Text Available FengYun-3 (FY-3 Visible Infrared Radiometer (VIRR, along with its predecessor, Multispectral Visible Infrared Scanning Radiometer (MVISR, onboard FY-1C&D have had continuous global observation more than 14 years. This data record is valuable for weather prediction, climate monitoring, and environment research. Data quality is vital for satellite data assimilations in Numerical Weather Prediction (NWP and quantitative remote sensing applications. In this paper, the accuracies of radiometric calibration for VIRR onboard FY-3A and FY-3B, in thermal infrared (TIR channels, are evaluated using the Low Earth Orbit (LEO-LEO simultaneous nadir overpass intercalibration method. Hyperspectral and high-quality observations from Infrared Atmosphere Sounding Instrument (IASI onboard METOP-A are used as reference. The biases of VIRR measurements with respect to IASI over one-and-a-half years indicate that the TIR calibration accuracy of FY-3B VIRR is better than that of FY-3A VIRR. The brightness temperature (BT measured by FY-3A/VIRR is cooler than that measured by IASI with monthly mean biases ranging from −2 K to −1 K for channel 4 and −1 K to 0.2 K for channel 5. Measurements from FY-3B/VIRR are more consistent with that from IASI, and the annual mean biases are 0.84 ± 0.16 K and −0.66 ± 0.18 K for channels 4 and 5, respectively. The BT biases of FY-3A/VIRR show scene temperature-dependence and seasonal variation, which are not found from FY-3B/VIRR BT biases. The temperature-dependent biases are shown to be attributed to the nonlinearity of detectors. New nonlinear correction coefficients of FY-3A/VIRR TIR channels are reevaluated using various collocation samples. Verification results indicate that the use of the new nonlinear correction can greatly correct the scene temperature-dependent and systematic biases.

  3. Assessment of Mars Atmospheric Temperature Retrievals from the Thermal Emission Spectrometer Radiances

    Science.gov (United States)

    Hoffman, Matthew J.; Eluszkiewicz, Janusz; Weisenstein, Deborah; Uymin, Gennady; Moncet, Jean-Luc

    2012-01-01

    Motivated by the needs of Mars data assimilation. particularly quantification of measurement errors and generation of averaging kernels. we have evaluated atmospheric temperature retrievals from Mars Global Surveyor (MGS) Thermal Emission Spectrometer (TES) radiances. Multiple sets of retrievals have been considered in this study; (1) retrievals available from the Planetary Data System (PDS), (2) retrievals based on variants of the retrieval algorithm used to generate the PDS retrievals, and (3) retrievals produced using the Mars 1-Dimensional Retrieval (M1R) algorithm based on the Optimal Spectral Sampling (OSS ) forward model. The retrieved temperature profiles are compared to the MGS Radio Science (RS) temperature profiles. For the samples tested, the M1R temperature profiles can be made to agree within 2 K with the RS temperature profiles, but only after tuning the prior and error statistics. Use of a global prior that does not take into account the seasonal dependence leads errors of up 6 K. In polar samples. errors relative to the RS temperature profiles are even larger. In these samples, the PDS temperature profiles also exhibit a poor fit with RS temperatures. This fit is worse than reported in previous studies, indicating that the lack of fit is due to a bias correction to TES radiances implemented after 2004. To explain the differences between the PDS and Ml R temperatures, the algorithms are compared directly, with the OSS forward model inserted into the PDS algorithm. Factors such as the filtering parameter, the use of linear versus nonlinear constrained inversion, and the choice of the forward model, are found to contribute heavily to the differences in the temperature profiles retrieved in the polar regions, resulting in uncertainties of up to 6 K. Even outside the poles, changes in the a priori statistics result in different profile shapes which all fit the radiances within the specified error. The importance of the a priori statistics prevents

  4. Topics in nuclear power

    Science.gov (United States)

    Budnitz, Robert J.

    2015-03-01

    The 101 nuclear plants operating in the US today are far safer than they were 20-30 years ago. For example, there's been about a 100-fold reduction in the occurrence of "significant events" since the late 1970s. Although the youngest of currently operating US plants was designed in the 1970s, all have been significantly modified over the years. Key contributors to the safety gains are a vigilant culture, much improved equipment reliability, greatly improved training of operators and maintenance workers, worldwide sharing of experience, and the effective use of probabilistic risk assessment. Several manufacturers have submitted high quality new designs for large reactors to the U.S. Nuclear Regulatory Commission (NRC) for design approval, and several companies are vigorously working on designs for smaller, modular reactors. Although the Fukushima reactor accident in March 2011 in Japan has been an almost unmitigated disaster for the local population due to their being displaced from their homes and workplaces and also due to the land contamination, its "lessons learned" have been important for the broader nuclear industry, and will surely result in safer nuclear plants worldwide - indeed, have already done so, with more safety improvements to come.

  5. Prospects in application of thermal analysis for assessing the total water potential of soils

    Science.gov (United States)

    Sudnitsyn, I. I.

    2016-10-01

    The theoretically derived dependence of the water vapor density (concentration) in the air on the absolute temperature permitted us to use the information obtained by thermogravimetric method for assessing the total potential of water remaining in colloids after drying at different temperatures. A close correlation and corresponding linear relationship fitting the fundamental physicochemical law by Landau-Derjaguin were observed between the logarithm modulus of the total potential of moisture left in soil colloids after drying at temperatures 27-70° and 70-200°C and their moisture. The total potential of water bound by hydrates and crystalline hydrates of substances in the soils varied in the range from-660 to-2394 J/g water, and that of water bound in soil clay minerals varied in the range from-714 to-2814 J/g water (which corresponds to the total soil water pressure of-7140 to-28140 atm.).

  6. Environmental assessment of the thermal neutron activation explosive detection system for concourse use at US airports

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.G.

    1990-08-01

    This document is an environmental assessment of a system designed to detect the presence of explosives in checked airline baggage or cargo. The system is meant to be installed at the concourse or lobby ticketing areas of US commercial airports and uses a sealed radioactive source of californium-252 to irradiate baggage items. The major impact of the use of this system arises from direct exposure of the public to scattered or leakage radiation from the source and to induced radioactivity in baggage items. Under normal operation and the most likely accident scenarios, the environmental impacts that would be created by the proposed licensing action would not be significant. 44 refs., 19 figs., 18 tabs.

  7. Thermal imaging for assessment of electron-beam freeform fabrication (EBF3) additive manufacturing deposits

    Science.gov (United States)

    Zalameda, Joseph N.; Burke, Eric R.; Hafley, Robert A.; Taminger, Karen M.; Domack, Christopher S.; Brewer, Amy; Martin, Richard E.

    2013-05-01

    Additive manufacturing is a rapidly growing field where 3-dimensional parts can be produced layer by layer. NASA's electron beam freeform fabrication (EBF3) technology is being evaluated to manufacture metallic parts in a space environment. The benefits of EBF3 technology are weight savings to support space missions, rapid prototyping in a zero gravity environment, and improved vehicle readiness. The EBF3 system is composed of 3 main components: electron beam gun, multi-axis position system, and metallic wire feeder. The electron beam is used to melt the wire and the multi-axis positioning system is used to build the part layer by layer. To insure a quality deposit, a near infrared (NIR) camera is used to image the melt pool and solidification areas. This paper describes the calibration and application of a NIR camera for temperature measurement. In addition, image processing techniques are presented for deposit assessment metrics.

  8. Mental Mechanisms for Topics Identification

    Directory of Open Access Journals (Sweden)

    Louis Massey

    2014-01-01

    Full Text Available Topics identification (TI is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM. We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly.

  9. Site specific risk assessment of an energy-from-waste thermal treatment facility in Durham Region, Ontario, Canada. Part A: Human health risk assessment.

    Science.gov (United States)

    Ollson, Christopher A; Knopper, Loren D; Whitfield Aslund, Melissa L; Jayasinghe, Ruwan

    2014-01-01

    The regions of Durham and York in Ontario, Canada have partnered to construct an energy-from-waste thermal treatment facility as part of a long term strategy for the management of their municipal solid waste. This paper presents the results of a comprehensive human health risk assessment for this facility. This assessment was based on extensive sampling of baseline environmental conditions (e.g., collection and analysis of air, soil, water, and biota samples) as well as detailed site specific modeling to predict facility-related emissions of 87 identified contaminants of potential concern. Emissions were estimated for both the approved initial operating design capacity of the facility (140,000 tonnes per year) and for the maximum design capacity (400,000 tonnes per year). For the 140,000 tonnes per year scenario, this assessment indicated that facility-related emissions are unlikely to cause adverse health risks to local residents, farmers, or other receptors (e.g., recreational users). For the 400,000 tonnes per year scenarios, slightly elevated risks were noted with respect to inhalation (hydrogen chloride) and infant consumption of breast milk (dioxins and furans), but only during predicted 'upset conditions' (i.e. facility start-up, shutdown, and loss of air pollution control) that represent unusual and/or transient occurrences. However, current provincial regulations require that additional environmental screening would be mandatory prior to expansion of the facility beyond the initial approved capacity (140,000 tonnes per year). Therefore, the potential risks due to upset conditions for the 400,000 tonnes per year scenario should be more closely investigated if future expansion is pursued.

  10. Importance of thermal effects and sea surface roughness for offshore wind resource assessment

    DEFF Research Database (Denmark)

    Lange, B.; Larsen, Søren Ejling; Højstrup, Jørgen;

    2004-01-01

    in the Danish Baltic Sea. Monin-Obukhov theory is often used for the description of the wind speed profile. From a given wind speed at one height, the profile is predicted using two parameters, Obukhov length and sea surface roughness. Different methods to estimate these parameters are discussed and compared......-Obukhov theory, a simple correction method to account for this effect has been developed and is tested in the same way. The models for the estimation of the sea surface roughness were found to lead only to small differences. For the purpose of wind resource assessment, even the assumption of a constant roughness......). The power output estimation has also been compared with the method of the resource estimation program WAsP. For the Rodsand data set the prediction error of WAsP is about 4%. For the extrapolation with Monin-Obukhov theory with different L and z(0) estimations, it is 5-9%. The simple wind profile correction...

  11. Assessment of a fiber-optic distributed-temperature-sensing system to monitor the thermal dynamics of vegetated roof

    Science.gov (United States)

    Cousiño, J. A.; Hausner, M. B.; Victorero, F.; Bonilla, C.; Gironas, J. A.; Vera, S.; Bustamante, W.; Rojas, V.; Pasten, P.; Suarez, F. I.

    2014-12-01

    Vegetated (green) roofs include a growing media and vegetation layer, and offer a range of benefits such as the reduction of: the heat island effect, rooftop runoff peak flows, roof surface temperatures, energy used for cooling or heating buildings, and noise levels inside infrastructures. Vegetated roofs also offer aesthetic benefits and increase the biodiversity of the urban environment, and are increasingly used in sustainable urban development. Understanding the thermal dynamics of vegetated roofs will make it possible to improve their design and to better assess their impacts on energy efficiency. Here, we evaluate the first vertical high-resolution distributed-temperature-sensing (DTS) system installed in a vegetated roof. This system allows a continuous measurement of the thermal profile within a vegetated roof - going from the interior, upward through the drainage layers and soil substrate of the vegetated roof and ending in the air above the vegetation. Temperatures can be observed as frequently as every 30 s at a spatial resolution on the order of centimeters. This DTS system was installed in the "Laboratory of Vegetal Infrastructure of Buildings" (LIVE - its acronym in Spanish), located in the San Joaquín Campus of the Pontifical Catholic University, Santiago, Chile. The laboratory features 18 experimental modules to investigate different configurations of the vegetated roof layers. The LIVE was designed with the installation of the optical fibers in mind, and the DTS system allows simultaneous monitoring of three or four modules of the LIVE. In this work, we describe the design of this DTS deployment, the calibration metrics obtained using the software provided by the manufacturers, and other calibration algorithms previously developed. We compare the results obtained using single- and double-ended measurements, highlighting strengths and weaknesses of DTS methods. Finally, we present the observations obtained from this biophysical environment

  12. Potential impact of enhanced fracture-toughness data on fracture mechanics assessment of PWR vessel integrity for pressurized thermal shock

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, T.L.; Theiss, T.J.

    1991-01-01

    The Heavy Section Steel Technology (HSST) Program is involved with the generation of enhanced fracture-initiation toughness and fracture-arrest toughness data of prototypic nuclear reactor vessel steels. These two sets of data are enhanced because they have distinguishing characteristics that could potentially impact PWR pressure vessel integrity assessments for the pressurized-thermal shock (PTS) loading condition which is a major plant-life extension issue to be confronted in the 1990's. A series of large-scale fracture-mechanics experiments have produced crack-arrest (K{sub Ia}) data with the distinguishing characteristic that the values are considerably above 220 MPA {center dot} {radical}m. The implicit limit of the ASME Code and the limit used in the Integrated Pressurized Thermal Shock (IPTS) studies. Currently, the HSST Program is planning experiments to verify and quantify for A533B steel the distinguishing characteristic of elevated the distinguishing characteristic of elevated initiation-fracture toughness for shallow flaws which has been observed for other steels. The results of the analyses indicated that application of the enhanced K{sub Ia} data does reduce the conditional probability of failure P(F{vert bar}E); however, it does not appear to have the potential to significantly impact the results of PTS analyses. The application of enhanced fracture-initiation-toughness data for shallow flaws also reduces P(F{vert bar}E), and does appear to have a potential for significantly affecting the results of PTS analyses. 19 refs., 11 figs., 1 tab.

  13. Erythromycin and Benzoyl Peroxide Topical

    Science.gov (United States)

    The combination of erythromycin and benzoyl peroxide is used to treat acne. Erythromycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of erythromycin ...

  14. Clindamycin and Benzoyl Peroxide Topical

    Science.gov (United States)

    The combination of clindamycin and benzoyl peroxide is used to treat acne. Clindamycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of clindamycin ...

  15. Safety and Health Topics: Asbestos

    Science.gov (United States)

    ... Videos E-Tools Safety and Health Topics / Asbestos Asbestos This page requires that javascript be enabled for ... Hazards and Toxic Substances Hazardous Waste What is asbestos? Asbestos is the name given to a group ...

  16. Thermal assessment of Shippingport pressurized water reactor blanket fuel assemblies within a multi-canister overpack within the canister storage building

    Energy Technology Data Exchange (ETDEWEB)

    HEARD, F.J.

    1999-04-09

    A series of analyses were performed to assess the thermal performance characteristics of the Shippingport Pressurized Water Reactor Core 2 Blanket Fuel Assemblies as loaded within a Multi-Canister Overpack within the Canister Storage Building. A two-dimensional finite element was developed, with enough detail to model the individual fuel plates: including the fuel wafers, cladding, and flow channels.

  17. Linguistic Extensions of Topic Models

    Science.gov (United States)

    2010-09-01

    class of corpora and would help monolingual users to explore and understand multilingual corpora. In this chapter, we develop multilingual LDAWN, an... Multilingual Priors As in the case of a monolingual walk over the concept hierarchy, we want to provide guidance to the multilingual model as to which parts...topic models for new datasets, such as unaligned multilingual corpora, and combine topic models with other sources of information about documents’ context

  18. Topics of Bioengineering in Wikipedia

    Directory of Open Access Journals (Sweden)

    Vassia Atanassova

    2009-10-01

    Full Text Available The present report aims to give a snapshot of how topics from the field of bioengineering (bioinformatics, bioprocess systems, biomedical engineering, biotechnology, etc. are currently covered in the free electronic encyclopedia Wikipedia. It also offers insights and information about what Wikipedia is, how it functions, how and when to cite Wikipedian articles, if necessary. Several external wikis, devoted to topics of bioengineering, are also listed and reviewed.

  19. Topics in modern differential geometry

    CERN Document Server

    Verstraelen, Leopold

    2017-01-01

    A variety of introductory articles is provided on a wide range of topics, including variational problems on curves and surfaces with anisotropic curvature. Experts in the fields of Riemannian, Lorentzian and contact geometry present state-of-the-art reviews of their topics. The contributions are written on a graduate level and contain extended bibliographies. The ten chapters are the result of various doctoral courses which were held in 2009 and 2010 at universities in Leuven, Serbia, Romania and Spain.

  20. Encyclopedia of thermal stresses

    CERN Document Server

    2014-01-01

    The Encyclopedia of Thermal Stresses is an important interdisciplinary reference work.  In addition to topics on thermal stresses, it contains entries on related topics, such as the theory of elasticity, heat conduction, thermodynamics, appropriate topics on applied mathematics, and topics on numerical methods. The Encyclopedia is aimed at undergraduate and graduate students, researchers and engineers. It brings together well established knowledge and recently received results. All entries were prepared  by leading experts from all over the world, and are presented in an easily accessible format. The work is lavishly illustrated, examples and applications are given where appropriate, ideas for further development abound, and the work will challenge many students and researchers to pursue new results of their own. This work can also serve as a one-stop resource for all who need succinct, concise, reliable and up to date information in short encyclopedic entries, while the extensive references will be of inte...

  1. Site specific risk assessment of an energy-from-waste/thermal treatment facility in Durham Region, Ontario, Canada. Part B: Ecological risk assessment.

    Science.gov (United States)

    Ollson, Christopher A; Whitfield Aslund, Melissa L; Knopper, Loren D; Dan, Tereza

    2014-01-01

    The regions of Durham and York in Ontario, Canada have partnered to construct an energy-from-waste (EFW) thermal treatment facility as part of a long term strategy for the management of their municipal solid waste. In this paper we present the results of a comprehensive ecological risk assessment (ERA) for this planned facility, based on baseline sampling and site specific modeling to predict facility-related emissions, which was subsequently accepted by regulatory authorities. Emissions were estimated for both the approved initial operating design capacity of the facility (140,000 tonnes per year) and the maximum design capacity (400,000 tonnes per year). In general, calculated ecological hazard quotients (EHQs) and screening ratios (SRs) for receptors did not exceed the benchmark value (1.0). The only exceedances noted were generally due to existing baseline media concentrations, which did not differ from those expected for similar unimpacted sites in Ontario. This suggests that these exceedances reflect conservative assumptions applied in the risk assessment rather than actual potential risk. However, under predicted upset conditions at 400,000 tonnes per year (i.e., facility start-up, shutdown, and loss of air pollution control), a potential unacceptable risk was estimated for freshwater receptors with respect to benzo(g,h,i)perylene (SR=1.1), which could not be attributed to baseline conditions. Although this slight exceedance reflects a conservative worst-case scenario (upset conditions coinciding with worst-case meteorological conditions), further investigation of potential ecological risk should be performed if this facility is expanded to the maximum operating capacity in the future.

  2. Thermal conductivity and thermal linear expansion measurements on molten salts for assessing their behaviour as heat transport fluid in thermodynamics solar systems

    Science.gov (United States)

    Coppa, P.; Bovesecchi, G.; Fabrizi, F.

    2010-08-01

    Molten salts (sodium and potassium nitrides) are going to be used in many different plants as heat transferring fluids, e.g. concentration solar plants, nuclear power plants, etc. In fact they present may important advantages: their absolute safety and non toxicity, availability and low cost. But their use, e.g. in the energy receiving pipe in the focus of the parabolic mirror concentrator of the solar thermodynamic plant, requires the accurate knowledge of the thermophysical properties, above all thermal conductivity, viscosity, specific heat and thermal linear expansion, in the temperature range 200°C÷600°C. In the new laboratory by ENEA Casaccia, SolTerm Department all these properties are going to be measured. Thermal conductivity is measured with the standard probe method (linear heat source inserted into the material) manufacturing a special probe suited to the foreseen temperature range (190-550°C). The probe is made of a ceramic quadrifilar pipe containing in different holes the heater (Ni wire) and the thermometer (type J thermocouple). The thermal linear expansion will be measured by a special system designed and built to this end, measuring the sample dilatation by the reflection of a laser beam by the bottom of the meniscus in the liquid solid interface. The viscosity will be evaluated detecting the start of the natural convection in the same experiment as to measure thermal conductivity. In the paper the construction of the devices, the results of preliminary tests and an evaluation of the obtainable accuracy are reported.

  3. Assessment Framework of Building Facade in Optimizing Indoor Thermal Comfort of Green Building Index (GBI Certified Office Building

    Directory of Open Access Journals (Sweden)

    Abdul Tharim Asniza Hamimi

    2016-01-01

    Full Text Available During the past decade, the construction industry has seen a new trend in the development of “green” or “sustainable” construction concept around the world with vast support from prominent organization, together with the introduction of sustainable building codes. The establishment of green building certification systems worldwide is seen as one of the most efforts in the emerging green building movement. In order to support the development of the “green” and “sustainable” concept in Malaysia, Green Building Index (GBI was launched by the government on 21 May 2009 that created to promote sustainability in the built environment and raise awareness of environmental issues. However, the construction industry seems to have focused only on findings the “right mechanism” for an environmentally sustainable “final result” in order for the building to be certified as green with the lacking of continuous assessment on the building performance after the certifications. This study is purposely conducted to investigate the performance of various rated Green Building Index (GBI Non-Residential New Construction office buildings and the influence on Indoor Thermal Comfort (ITC of the selected buildings. The aim is to develop an assessment framework for optimum green building architectural façade to be used for office buildings in Malaysia as well as to analyse the occupants’ perception, satisfaction and performance in the selected Green Building Index (GBI rated office indoor environment. This research is still in its infancy; therefore the paper is focused on research aims, research scope and methodology, and expected deliverables for the proposed research.

  4. Quantitative assessment of the relationship between radiant heat exposure and protective performance of multilayer thermal protective clothing during dry and wet conditions.

    Science.gov (United States)

    Fu, M; Weng, W G; Yuan, H Y

    2014-07-15

    The beneficial effect of clothing on a person is important to the criteria for people exposure to radiant heat flux from fires. The thermal protective performance of multilayer thermal protective clothing exposed to low heat fluxes during dry and wet conditions was studied using two designed bench-scale test apparatus. The protective clothing with four fabric layers (outer shell, moisture barrier, thermal linear and inner layer) was exposed to six levels of thermal radiation (1, 2, 3, 5, 7 and 10kW/m(2)). Two kinds of the moisture barrier (PTFE and GoreTex) with different vapor permeability were compared. The outside and inside surface temperatures of each fabric layer were measured. The fitting analysis was used to quantitatively assess the relationship between the temperature of each layer during thermal exposure and the level of external heat flux. It is indicated that there is a linear correlation between the temperature of each layer and the radiant level. Therefore, a predicted equation is developed to calculate the thermal insulation of the multilayer clothing from the external heat flux. It can also provide some useful information on the beneficial effects of clothing for the exposure criteria of radiant heat flux from fire.

  5. Solar Thermal Propulsion

    Science.gov (United States)

    Gerrish, Harold P., Jr.

    2003-01-01

    This paper presents viewgraphs on Solar Thermal Propulsion (STP). Some of the topics include: 1) Ways to use Solar Energy for Propulsion; 2) Solar (fusion) Energy; 3) Operation in Orbit; 4) Propulsion Concepts; 5) Critical Equations; 6) Power Efficiency; 7) Major STP Projects; 8) Types of STP Engines; 9) Solar Thermal Propulsion Direct Gain Assembly; 10) Specific Impulse; 11) Thrust; 12) Temperature Distribution; 13) Pressure Loss; 14) Transient Startup; 15) Axial Heat Input; 16) Direct Gain Engine Design; 17) Direct Gain Engine Fabrication; 18) Solar Thermal Propulsion Direct Gain Components; 19) Solar Thermal Test Facility; and 20) Checkout Results.

  6. Selecting a Topic in Public Speaking

    Institute of Scientific and Technical Information of China (English)

    刘玉霞

    2013-01-01

    The first step in speechmaking is choosing a topic, which will decide the success of the speech. In the paper, we are go⁃ing to discuss how to select a topic in public speaking, and we’ll mainly talk about the following: the speaker, the occasion and the audience, selecting a topic, specific methods for choosing a topic and available topics.

  7. Topical agents in burn care

    Directory of Open Access Journals (Sweden)

    Momčilović Dragan

    2002-01-01

    Full Text Available Introduction Understanding of fluid shifts and recognition of the importance of early and appropriate fluid replacement therapy have significantly reduced mortality in the early post burn period. After the bum patient successfully passes the resuscitation period, the burn wound represents the greatest threat to survival. History Since the dawn of civilization, man has been trying to find an agent which would help burn wounds heal, and at the same time, not harm general condition of the injured. It was not until the XX century, after the discovery of antibiotics, when this condition was fulfilled. In 1968, combining silver and sulfadiazine, fox made silver-sulfadiazine, which is a 1% hydro-soluble cream and a superior agent in topical treatment of burns today. Current topical agents None of the topical antimicrobial agents available today, alone or combined, have the characteristics of ideal prophylactic agents, but they eliminate colonization of burn wound, and invasive infections are infrequent. With an excellent spectrum of activity, low toxicity, and ease of application with minimal pain, silver-sulfadiazine is still the most frequently used topical agent. Conclusion The incidence of invasive infections and overall mortality have been significantly reduced after introduction of topical burn wound antimicrobial agents into practice. In most burn patients the drug of choice for prophylaxis is silver sulfadiazine. Other agents may be useful in certain clinical situations.

  8. Assessment and Accommodation of Thermal Expansion of the Internal Active Thermal Control System Coolant During Launch to On-Orbit Activation of International Space Station Elements

    Science.gov (United States)

    Edwards, Darryl; Ungar, Eugene K.; Holt, James M.

    2002-01-01

    The International Space Station (ISS) employs an Internal Active Thermal Control System (IATCS) comprised of several single-phase water coolant loops. These coolant loops are distributed throughout the ISS pressurized elements. The primary element coolant loops (i.e. U.S. Laboratory module) contain a fluid accumulator to accomodate thermal expansion of the system. Other element coolant loops are parasitic (i.e. Airlock), have no accumulator, and require an alternative approach to insure that the system maximum design pressure (MDP) is not exceeded during the Launch to Activation (LTA) phase. During this time the element loops is a stand alone closed system. The solution approach for accomodating thermal expansion was affected by interactions of system components and their particular limitations. The mathematical solution approach was challenged by the presence of certain unknown or not readily obtainable physical and thermodynamic characteristics of some system components and processes. The purpose of this paper is to provide a brief description of a few of the solutions that evolved over time, a novel mathematical solution to eliminate some of the unknowns or derive the unknowns experimentally, and the testing and methods undertaken.

  9. Drivers of Plant-Availability of Phosphorus from Thermally Conditioned Sewage Sludge as Assessed by Isotopic Labeling

    Science.gov (United States)

    Andriamananjara, Andry; Rabeharisoa, Lilia; Prud’homme, Loïc; Morel, Christian

    2016-01-01

    Urban sewage sludge is a potential source of phosphorus (P) for agriculture and represents an alternative way to recycle P as fertilizer. However, the use of thermally conditioned sewage sludge (TCSS) required an accurate assessment of its value as P-fertilizer. This work aimed at assessing the plant-availability of P from TCSS. Uptake of P by a mixture of ryegrass and fescue from TCSS and triple super phosphate (TSP) fertilizers was studied using 32P-labeling technique in a greenhouse experiment. Phosphorus was applied at the rate of 50 mg P kg−1.We also conducted incubation experiments considering the same treatments to assess soil microbial respiration. Applications of TCSS and TSP increased plant P uptake that is related to the root P acquisition. The P taken up by plant from soil plant-available P was lower for control compared to TSP or TCSS that was attributed to the increase of root interception of soil P. The contribution of TSP to ryegrass nutrition (Pdff%) was 55% with 22% of the applied P which was taken up by plants (CPU%). The Pdff value for TCSS was 56% with 14% of fertilizer P recovery (CPU%). Shoot biomass and total P uptake from TCSS were lower than those from TSP. As a result, the agronomic effectiveness of TCSS calculated from Pdff value (in comparison with TSP treatment) was 102%, while the AE of TCSS estimated from CPU value (in % TSP) was 64%, which is attributed to microbial activity stimulation inducing P immobilization onto soil constituents and microbial biomass during plant growth. The high C/N ratio of TCSS stimulated soil microbial biomass that competes with plant roots to acquire nutrients, such as P. As a consequence, the P taken up from either native soil or TCSS decreased in similar proportions. The AE value calculated with Pdff% took into account these interactions between soil, plant, and microbial biomass, and is less dependent on operational conditions than the AE value calculated with %Precovery. PMID:27379240

  10. Quantum mechanics II advanced topics

    CERN Document Server

    Rajasekar, S

    2015-01-01

    Quantum Mechanics II: Advanced Topics uses more than a decade of research and the authors’ own teaching experience to expound on some of the more advanced topics and current research in quantum mechanics. A follow-up to the authors introductory book Quantum Mechanics I: The Fundamentals, this book begins with a chapter on quantum field theory, and goes on to present basic principles, key features, and applications. It outlines recent quantum technologies and phenomena, and introduces growing topics of interest in quantum mechanics. The authors describe promising applications that include ghost imaging, detection of weak amplitude objects, entangled two-photon microscopy, detection of small displacements, lithography, metrology, and teleportation of optical images. They also present worked-out examples and provide numerous problems at the end of each chapter.

  11. A Green's function approach for assessing the thermal disturbance caused by drilling deep boreholes in rock or ice

    Science.gov (United States)

    Clow, Gary D.

    2015-01-01

    A knowledge of subsurface temperatures in sedimentary basins, fault zones, volcanic environments and polar ice sheets is of interest for a wide variety of geophysical applications. However, the process of drilling deep boreholes in these environments to provide access for temperature and other measurements invariably disturbs the temperature field around a newly created borehole. Although this disturbance dissipates over time, most temperature measurements are made while the temperature field is still disturbed. Thus, the measurements must be ‘corrected’ for the drilling-disturbance effect if the undisturbed temperature field is to be determined. This paper provides compact analytical solutions for the thermal drilling disturbance based on 1-D (radial) and 2-D (radial and depth) Green's functions (GFs) in cylindrical coordinates. Solutions are developed for three types of boundary conditions (BCs) at the borehole wall: (1) prescribed temperature, (2) prescribed heat flux and (3) a prescribed convective condition. The BC at the borehole wall is allowed to vary both with depth and time. Inclusion of the depth dimension in the 2-D solution allows vertical heat-transfer effects to be quantified in situations where they are potentially important, that is, near the earth's surface, at the bottom of a well and when considering finite-drilling rates. The 2-D solution also includes a radial- and time-dependent BC at the earth's surface to assess the impact of drilling-related infrastructure (drilling pads, mud pits, permanent shelters) on the subsurface temperature field. Latent-heat effects due to the melting and subsequent refreezing of interstitial ice while drilling a borehole through ice-rich permafrost can be included in the GF solution as a moving-plane heat source (or sink) located at the solid–liquid interface. Synthetic examples are provided illustrating the 1-D and 2-D GF solutions. The flexibility of the approach allows the investigation of thermal

  12. An analysis of topic areas and topic trends in the Community Mental Health Journal from 1965 through 1977.

    Science.gov (United States)

    Lounsbury, J W; Roisum, K G; Pokorny, L; Sills, A; Meissen, G J

    1979-01-01

    A content analysis of all (N = 604) published articles in the Community Mental Health Journal from 1965 through 1977 was performed (a) to provide a cross-sectional view of the community mental health field, and (b) to identify topic trends over time. Sixty-one content categories were used to classify topic areas. Results revealed major and growing emphases on organizing for the delivery and measuring of the effects of mental health service systems. Topics found to be increasing in relative frequency over time included training, measurement and research methodology, and intervention; those decreasing included planning and needs assessment, therapy, and suicide. Topic areas were compared with key characteristics of the field. Topic trends were interpreted in terms of open systems theory.

  13. Topical therapies in hyperhidrosis care.

    Science.gov (United States)

    Pariser, David M; Ballard, Angela

    2014-10-01

    Primary focal hyperhidrosis affects 3% of the US population; about the same number as psoriasis. More than half of these patients have primary focal axillary hyperhidrosis: sweating that is beyond what is anticipated or necessary for thermoregulation. Most topical therapies are based on aluminum salts, which work by a chemical reaction that forms plugs in the eccrine sweat ducts. Topical anticholinergics may also be used. Instruction on proper methods and timing of antiperspirants enhances effect and may be effective alone or in combination with other treatments in patients with hyperhidrosis.

  14. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  15. Topics in millimeter wave technology

    CERN Document Server

    Button, Kenneth

    1988-01-01

    Topics in Millimeter Wave Technology, Volume 1 presents topics related to millimeter wave technology, including fin-lines and passive components realized in fin-lines, suspended striplines, suspended substrate microstrips, and modal power exchange in multimode fibers. A miniaturized monopulse assembly constructed in planar waveguide with multimode scalar horn feeds is also described. This volume is comprised of five chapters; the first of which deals with the analysis and synthesis techniques for fin-lines as well as the various passive components realized in fin-line. Tapers, discontinuities,

  16. TOPICAL REVIEW: Nanoscience and nanotechnology in Europe

    Science.gov (United States)

    Tolles, W. M.

    1996-06-01

    During six months from April to September 1994, the author visited 42 laboratories in eight different European countries involved with research in nanostructures. The scientific thrusts point the way to new methods and properties of matter that may provide useful information. The potential applications of research in this field are likely to be found in information technology, sensors, and new materials, replete with the implications for many industrial interests. It is a suitable topic for the recently introduced `focused technical assessment' activities of the Office of Naval Research Europe where the coordination for this effort was focused. Overviews of multidisciplinary efforts in fields of physics, electrical engineering, materials, chemistry, and biology are presented.

  17. Review of topical beta blockers as treatment for infantile hemangiomas.

    Science.gov (United States)

    Painter, Sally L; Hildebrand, Göran Darius

    2016-01-01

    The treatment of infantile hemangiomas changed from the use of oral corticosteroids to oral propranolol on the serendipitous discovery of propanolol's clinical effectiveness in 2008. Since then, clinicians have begun to use topical beta blockers--in particular, timolol maleate 0.5% gel forming solution--with good effect. Topical beta blockers are now used for lesions with both deep and superficial components and those that are amblyogenic. When initiated in the proliferative phase of the lesion, the effectiveness of the treatment can be seen within days. There is no consensus on dosing, treatment bioavailability, or clinical assessment of lesions, but these are topics for future research.

  18. Automatic Labelling of Topics with Neural Embeddings

    OpenAIRE

    Bhatia, Shraey; Lau, Jey Han; Baldwin, Timothy

    2016-01-01

    Topics generated by topic models are typically represented as list of terms. To reduce the cognitive overhead of interpreting these topics for end-users, we propose labelling a topic with a succinct phrase that summarises its theme or idea. Using Wikipedia document titles as label candidates, we compute neural embeddings for documents and words to select the most relevant labels for topics. Compared to a state-of-the-art topic labelling system, our methodology is simpler, more efficient, and ...

  19. Safety of topical medications for scabies and lice in pregnancy

    Directory of Open Access Journals (Sweden)

    Viral M Patel

    2016-01-01

    Full Text Available Medications should be employed with caution in women of childbearing age. Topical medications have little systemic absorption. Therefore, they are considered safer than oral or parenteral agents and less likely to be embryotoxic or fetotoxic. However, their safety profile must be assessed cautiously as the available data are limited. In this article, we aggregate human and animal studies to provide recommendations on using topical anti-scabies and anti-lice therapy in pregnancy.

  20. Total System Performance Assessment- License Application Design Selection (LADS) Phase 1 Analysis for Higher Thermal Loa (Feature 26)

    Energy Technology Data Exchange (ETDEWEB)

    N. Erb

    1999-06-11

    The objective of this report is to evaluate the effect of potential changes to the TSPA-VA base case design on long-term repository performance. The design feature that is evaluated in this report is a higher thermal load (Feature 26 or F26). The following paragraph briefly describes the motivation for evaluating higher thermal loading. Higher thermal load has been identified as a design feature that might have a beneficial effect on long-term repository performance. A higher thermal load will increase temperatures and decrease relative humidity on the waste package surface. The decrease in relative humidity may delay the onset of corrosion, thus delaying the failure of waste packages and the release of radionuclides from the engineered barrier system (EBS). For the current calculation a thermal load of 109 MTU/acre (metric tons of uranium per acre) is considered. Two cases are evaluated, one with the base case inventory and a higher thermal load and a second with an increased inventory that would cover the current repository footprint at the higher thermal load. This report documents the modeling assumptions and calculations conducted to evaluate the long-term performance of higher thermal loading. The performance measure for this evaluation is dose-rate. Results are presented that compare the dose-rate time histories with the new design feature to that for the TSPA-VA base case calculation (CRWMS M&O, 1998a).

  1. Seven topics in perturbative QCD

    Energy Technology Data Exchange (ETDEWEB)

    Buras, A.J.

    1980-09-01

    The following topics of perturbative QCD are discussed: (1) deep inelastic scattering; (2) higher order corrections to e/sup +/e/sup -/ annihilation, to photon structure functions and to quarkonia decays; (3) higher order corrections to fragmentation functions and to various semi-inclusive processes; (4) higher twist contributions; (5) exclusive processes; (6) transverse momentum effects; (7) jet and photon physics.

  2. The Health Curriculum: 500 Topics.

    Science.gov (United States)

    Byrd, Oliver E.

    2001-01-01

    This 1958 paper divides 500 health topics into 20 categories: health as a social accomplishment/social problem; nutrition; physical fitness; mental health and disease; heredity/eugenics; infection/immunity; chronic and degenerative disease; substance abuse; skin care; vision, hearing, and speech; dental health; safety; physical environment; health…

  3. Topics in combinatorial pattern matching

    DEFF Research Database (Denmark)

    Vildhøj, Hjalte Wedel

    This dissertation studies problems in the general theme of combinatorial pattern matching. More specifically, we study the following topics: Longest Common Extensions. We revisit the longest common extension (LCE) problem, that is, preprocess a string T into a compact data structure that supports...

  4. A multi-criteria assessment of scenarios on thermal processing of infectious hospital wastes: a case study for Central Macedonia.

    Science.gov (United States)

    Karagiannidis, A; Papageorgiou, A; Perkoulidis, G; Sanida, G; Samaras, P

    2010-02-01

    In Greece more than 14,000 tonnes of infectious hospital waste are produced yearly; a significant part of it is still mismanaged. Only one off-site licensed incineration facility for hospital wastes is in operation, with the remaining of the market covered by various hydroclave and autoclave units, whereas numerous problems are still generally encountered regarding waste segregation, collection, transportation and management, as well as often excessive entailed costs. Everyday practices still include dumping the majority of solid hospital waste into household disposal sites and landfills after sterilization, still largely without any preceding recycling and separation steps. Discussed in the present paper are the implemented and future treatment practices of infectious hospital wastes in Central Macedonia; produced quantities are reviewed, actual treatment costs are addressed critically, whereas the overall situation in Greece is discussed. Moreover, thermal treatment processes that could be applied for the treatment of infectious hospital wastes in the region are assessed via the multi-criteria decision method Analytic Hierarchy Process. Furthermore, a sensitivity analysis was performed and the analysis demonstrated that a centralized autoclave or hydroclave plant near Thessaloniki is the best performing option, depending however on the selection and weighing of criteria of the multi-criteria process. Moreover the study found that a common treatment option for the treatment of all infectious hospital wastes produced in the Region of Central Macedonia, could offer cost and environmental benefits. In general the multi-criteria decision method, as well as the conclusions and remarks of this study can be used as a basis for future planning and anticipation of the needs for investments in the area of medical waste management.

  5. International Space Station (ISS) External Thermal Control System (ETCS) Loop A Pump Module (PM) Jettison Options Assessment

    Science.gov (United States)

    Murri, Daniel G.; Dwyer Cianciolo, Alicia; Shidner, Jeremy D.; Powell, Richard W.

    2014-01-01

    On December 11, 2013, the International Space Station (ISS) experienced a failure of the External Thermal Control System (ETCS) Loop A Pump Module (PM). To minimize the number of extravehicular activities (EVA) required to replace the PM, jettisoning the faulty pump was evaluated. The objective of this study was to independently evaluate the jettison options considered by the ISS Trajectory Operations Officer (TOPO) and to provide recommendations for safe jettison of the ETCS Loop A PM. The simulation selected to evaluate the TOPO options was the NASA Engineering and Safety Center's (NESC) version of Program to Optimize Simulated Trajectories II (POST2) developed to support another NESC assessment. The objective of the jettison analysis was twofold: (1) to independently verify TOPO posigrade and retrograde jettison results, and (2) to determine jettison guidelines based on additional sensitivity, trade study, and Monte Carlo (MC) analysis that would prevent PM recontact. Recontact in this study designates a propagated PM trajectory that comes within 500 m of the ISS propagated trajectory. An additional simulation using Systems Tool Kit (STK) was run for independent verification of the POST2 simulation results. Ultimately, the ISS Program removed the PM jettison option from consideration. However, prior to the Program decision, the retrograde jettison option remained part of the EVA contingency plan. The jettison analysis presented showed that, in addition to separation velocity/direction and the atmosphere conditions, the key variables in determining the time to recontact the ISS is highly dependent on the ballistic number (BN) difference between the object being jettisoned and the ISS.

  6. The pharmacology of topical analgesics.

    Science.gov (United States)

    Barkin, Robert L

    2013-07-01

    Pain management of patients continues to pose challenges to clinicians. Given the multiple dimensions of pain--whether acute or chronic, mild, moderate, or severe, nociceptive or neuropathic--a multimodal approach may be needed. Fortunately, clinicians have an array of nonpharmacologic and pharmacologic treatment choices; however, each modality must be chosen carefully, because some often used oral agents are associated with safety and tolerability issues that restrict their use in certain patients. In particular, orally administered nonsteroidal antiinflammatory drugs, opioids, antidepressants, and anticonvulsants are known to cause systemic adverse effects in some patients. To address this problem, a number of topical therapies in various therapeutic classes have been developed to reduce systemic exposure and minimize the risks of patients developing adverse events. For example, topical nonsteroidal anti-inflammatory drug formulations produce a site-specific effect (ie, cyclo-oxygenase inhibition) while decreasing the systemic exposure that may lead to undesired effects in patients. Similarly, derivatives of acetylsalicylic acid (ie, salicylates) are used in topical analgesic formulations that do not significantly enter the patient's systemic circulation. Salicylates, along with capsaicin, menthol, and camphor, compose the counterirritant class of topical analgesics, which produce analgesia by activating and then desensitizing epidermal nociceptors. Additionally, patches and creams that contain the local anesthetic lidocaine, alone or co-formulated with other local anesthetics, are also used to manage patients with select acute and chronic pain states. Perhaps the most common topical analgesic modality is the cautious application of cutaneous cold and heat. Such treatments may decrease pain not by reaching the target tissue through systemic distribution, but by acting more directly on the affected tissue. Despite the tolerability benefits associated with avoiding

  7. Life Cycle Assessment of Thermal Treatment Technologies. An environmental and financial systems analysis of gasification, incineration and landfilling of waste

    Energy Technology Data Exchange (ETDEWEB)

    Assefa, Getachew; Eriksson, Ola [Royal Inst. of Tech., Stockholm (Sweden). Industrial Ecology; Jaeraas, Sven; Kusar, Henrik [Royal Inst. of Tech., Stockholm (Sweden). Chemical Technology

    2003-05-01

    A technology which is currently developed by researchers at KTH is catalytic combustion. which is one component of a gasification system. Instead of performing the combustion in the gas turbine by a flame, a catalyst is used. When the development of a new technology (as catalytic combustion) reaches a certain step where it is possible to quantify material-, energy- and capital flows, the prerequisites for performing a systems analysis is at hand. The systems analysis can be used to expand the know-how about the potential advantages of the catalytic combustion technology by highlighting its function as a component of a larger system. In this way it may be possible to point out weak points which have to be investigated more, but also strong points to emphasise the importance of further development. The aim of this project was to assess the energy turnover as well as the potential environmental impacts and economic costs of thermal treatment technologies in general and catalytic combustion in particular. By using a holistic assessment of the advantages and disadvantages of catalytic combustion of waste it was possible to identify the strengths and weaknesses of the technology under different conditions. Following different treatment scenarios have been studied: (1) Gasification with catalytic combustion, (2) Gasification with flame combustion, (3) Incineration with energy recovery and (4) Landfilling with gas collection. In the study compensatory district heating is produced by combustion. of biofuel. The power used for running the processes in the scenarios is supplied by the waste-to-energy technologies themselves while compensatory power is assumed to be produced. from natural gas. The emissions from the system studied were classified and characterised using methodology from Life Cycle Assessment into the following environmental impact categories: Global Warming Potential, Acidification Potential, Eutrophication Potential and finally Formation of Photochemical

  8. Influence of Nodalization on Major Thermal-Hydraulic Variables Governing Mark-I Containment Response to an SBO Sequence: Plant Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Herranz, L. E.; Fontanet, J.; Fernandez, E.; Lopez, C.

    2014-07-01

    Simulating a severe accident with lumped parameter codes, like MELCOR 2.1, requires defining a suitable nodalization of the plant. In particular, the number of nodes the wet-well (WW) is divided into and the way these nodes are interconnected have an important effect on thermal-hydraulics estimates of the containment. Therefore, a quantitative assessment of the effect of WW nodalization on accident sequence is needed when performing plant analyses. (Author)

  9. Effects on topic familiarity on online search behaviour and use of relevance criteria

    DEFF Research Database (Denmark)

    Wen, Lei; Ruthven, Ian; Borlund, Pia

    2006-01-01

    This paper presents an experimental study on the effect of topic familiarity on the assessment behaviour of online searchers. In particular we investigate the effect of topic familiarity on the resources and relevance criteria used by searchers. Our results indicate that searching on an unfamiliar...... topic leads to use of more generic and fewer specialised resources and that searchers employ different relevance criteria when searching on less familiar topics....

  10. Comparison of UTCI with other thermal indices in the assessment of heat and cold effects on cardiovascular mortality in the Czech Republic

    Science.gov (United States)

    Urban, Ales; Kyselý, Jan

    2014-05-01

    Several studies have compared various human thermal comfort indices as to their applications in evaluating heat-related mortality. Much less attention has been devoted to application of thermal indices in evaluating cold-related mortality. So far, only a few studies have examined performance of the Universal Thermal Climate Index (UTCI), one of the most advanced indicators of biometeorological conditions, in assessing heat- and cold-related mortality. We compare UTCI and other selected thermal indices in analysing heat- and cold-related effects on cardiovascular (CVD) mortality in two different (urban and rural) regions in the Czech Republic during the 16-year period of 1994-2009. Excess mortality is represented by the number of deaths above expected daily values, the latter being adjusted for long-term changes, annual and weekly cycles, and epidemics of influenza/acute respiratory infections. The association between excess CVD mortality and air temperature, UTCI, Physiologically Equivalent Temperature (PET), and Apparent Temperature (AT) is analyzed using Poisson generalized additive models (GAMs). Heat- / cold-stress days are identified by percentiles of (equivalent) temperature distribution in summer / winter. We found air temperature (as the most widely used proxy for ambient thermal conditions in environmental epidemiology) comparable to thermal indices in assessing heat-related mortality. On the other hand, air temperature provides a weak cold effect in comparison with the thermal indices in both regions and its application may underestimate the magnitude of cold-related mortality. These findings are important when possible climate change effects on heat- and cold-related mortality are estimated. AT and PET appear to be more universal predictors of heat- and cold- related mortality than UTCI when both urban and rural environments are of concern. UTCI tends to select windy rather than freezing days in winter, though these show little effect on mortality in the

  11. Assessment of generic solar thermal systems for large power applications. Volume II. Analysis of thermal energy production costs for systems from 50 to 600 MWt

    Energy Technology Data Exchange (ETDEWEB)

    Bird, S.P.; Apley, W.J.; Barnhart, J.S.; Brown, D.R.; Drost, M.K.; Fort, J.A.; Garrett-Price, B.A.; Williams, T.A.

    1981-06-01

    A comparative analysis of solar thermal concepts that are potentially suitable for development as large process heat systems (50 to 600 MWt) was performed. The concepts considered can be classified into three categories based on the type of solar tracking used by the collector: (1) two-axis tracking, in which concentrators track the sun's motion in both azimuth and altitude; (2) one-axis tracking, in which concentrators track changes in either azimuth or altitude; and (3) non-tracking, in which the concentrators are fixed. Seven generic types of collectors were considered. Conceptual designs developed for the seven systems were based on common assumptions of available technology in the 1990 to 2000 time frame. Costs were estimated on the basis of identical assumptions, ground rules, methodologies, and unit costs of materials and labor applied uniformly to all of the concepts.

  12. Hot topics in functional neuroradiology.

    Science.gov (United States)

    Faro, S H; Mohamed, F B; Helpern, J A; Jensen, J H; Thulborn, K R; Atkinson, I C; Sair, H I; Mikulis, D J

    2013-12-01

    Functional neuroradiology represents a relatively new and ever-growing subspecialty in the field of neuroradiology. Neuroradiology has evolved beyond anatomy and basic tissue signal characteristics and strives to understand the underlying physiologic processes of central nervous system disease. The American Society of Functional Neuroradiology sponsors a yearly educational and scientific meeting, and the educational committee was asked to suggest a few cutting-edge functional neuroradiology techniques (hot topics). The following is a review of several of these topics and includes "Diffusion Tensor Imaging of the Pediatric Spinal Cord"; "Diffusional Kurtosis Imaging"; "From Standardization to Quantification: Beyond Biomarkers toward Bioscales as Neuro MR Imaging Surrogates of Clinical End Points"; Resting-State Functional MR Imaging"; and "Current Use of Cerebrovascular Reserve Imaging."

  13. Retapamulin: A newer topical antibiotic

    Directory of Open Access Journals (Sweden)

    D Dhingra

    2013-01-01

    Full Text Available Impetigo is a common childhood skin infection. There are reports of increasing drug resistance to the currently used topical antibiotics including fusidic acid and mupirocin. Retapamulin is a newer topical agent of pleuromutilin class approved by the Food and Drug Administration for treatment of impetigo in children and has been recently made available in the Indian market. It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram-positive bacteria found in skin infections including Staphylococcus aureus strains. The drug is safe owing to low systemic absorption and has only minimal side-effect of local irritation at the site of application.

  14. Do scientists trace hot topics?

    Science.gov (United States)

    Wei, Tian; Li, Menghui; Wu, Chensheng; Yan, Xiao-Yong; Fan, Ying; Di, Zengru; Wu, Jinshan

    2013-01-01

    Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects.

  15. Topics on nonlinear generalized functions

    CERN Document Server

    Colombeau, J F

    2011-01-01

    The aim of this paper is to give the text of a recent introduction to nonlinear generalized functions exposed in my talk in the congress gf2011, which was asked by several participants. Three representative topics were presented: two recalls "Nonlinear generalized functions and their connections with distribution theory", "Examples of applications", and a recent development: "Locally convex topologies and compactness: a functional analysis of nonlinear generalized functions".

  16. Topical Ocular Delivery of NSAIDs

    OpenAIRE

    Ahuja, Munish; Avinash S Dhake; Sharma, Surendra K; Dipak K Majumdar

    2008-01-01

    In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak acids with pKa mostly between 3.5 a...

  17. Topic Detection in Online Chat

    Science.gov (United States)

    2009-09-01

    including the time for reviewing instruction, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the...you. “ … Of making many books there is no end, and much study is a weariness of the flesh.” Ecclesiastes 12:12 , ESV xvi THIS PAGE INTENTIONALLY...topic detection," Online Information Review , vol. 30, pp. 496–516, 2006. [2] D. Jurafsky and J. H. Martin, Speech and Language Processing : An

  18. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1983-01-01

    Probabilistic Analysis and Related Topics, Volume 3 focuses on the continuity, integrability, and differentiability of random functions, including operator theory, measure theory, and functional and numerical analysis. The selection first offers information on the qualitative theory of stochastic systems and Langevin equations with multiplicative noise. Discussions focus on phase-space evolution via direct integration, phase-space evolution, linear and nonlinear systems, linearization, and generalizations. The text then ponders on the stability theory of stochastic difference systems and Marko

  19. Stochastic Analysis and Related Topics

    CERN Document Server

    Ustunel, Ali

    1988-01-01

    The Silvri Workshop was divided into a short summer school and a working conference, producing lectures and research papers on recent developments in stochastic analysis on Wiener space. The topics treated in the lectures relate to the Malliavin calculus, the Skorohod integral and nonlinear functionals of white noise. Most of the research papers are applications of these subjects. This volume addresses researchers and graduate students in stochastic processes and theoretical physics.

  20. Hot topics from the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Glenzinski, D.; /Fermilab

    2008-01-01

    The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

  1. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1979-01-01

    Probabilistic Analysis and Related Topics, Volume 2 focuses on the integrability, continuity, and differentiability of random functions, as well as functional analysis, measure theory, operator theory, and numerical analysis.The selection first offers information on the optimal control of stochastic systems and Gleason measures. Discussions focus on convergence of Gleason measures, random Gleason measures, orthogonally scattered Gleason measures, existence of optimal controls without feedback, random necessary conditions, and Gleason measures in tensor products. The text then elaborates on an

  2. Assessment on 900–1300 MWe PWRs of the ASTEC-based simulation tool of SGTR thermal-hydraulics for the IRSN Emergency Technical Centre

    Energy Technology Data Exchange (ETDEWEB)

    Foucher, L., E-mail: laurent.foucher@irsn.fr [Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PSN-RES/SAG, Cadarache, Saint-Paul-lez-Durance 13115 (France); Cousin, F.; Fleurot, J. [Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PSN-RES/SAG, Cadarache, Saint-Paul-lez-Durance 13115 (France); Brethes, S. [Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PRP-CRI/SESUC, Cadarache, Saint-Paul-lez-Durance 13115 (France)

    2014-06-01

    In the event of an accident occurring in a nuclear power plant (NPP), being able to predict the amount of released radioactive substances in the environment is of prime importance. Depending on the severity of the accident, it can be necessary to quickly and efficiently protect the population and the surrounding environment from the associated radiological consequences. In France, the IRSN Emergency Technical Centre provides a technical support in decision making in case of a nuclear accident. The main objectives are to evaluate and predict the plant behaviour and radioactive releases during the accident. Different types of complementary tools are used: expert assessments, pre-calculated databases, simulation tools, etc. In the case of Steam Generator Tube Rupture (SGTR) accidents that may lead to significant radioactive releases to the atmosphere through the steam generator relief valves, IRSN is currently improving the simulation tools for diagnosis in crisis management. The objective is to adapt the thermal-hydraulic and FP behaviour modules of the severe accident integral code ASTEC V2.0, jointly developed by IRSN and its German counterpart GRS, to crisis management requirements. These requirements impose a fast running, highly reliable (accurate physical results), flexible and simple tool. This paper summarizes the results of the benchmarks between the ASTEC V2.0 thermal-hydraulic module and the CATHARE 2 (V2.5) French reference thermal-hydraulics code on several SGTR scenarios both for PWR 900 and 1300 MWe, with a particular emphasis on the computational time and physical models assessment. The overall agreement between both codes is good on the primary and secondary circuit thermal-hydraulic parameters. Moreover, the reliability and fast computational time of the thermal-hydraulic module of ASTEC V2.0 code appeared very satisfactory and in accordance with the requirements of an emergency tool.

  3. Negative thermal expansion

    Energy Technology Data Exchange (ETDEWEB)

    Barrera, G D [Departamento de QuImica, Universidad Nacional de la Patagonia SJB, Ciudad Universitaria, 9000 Comodoro Rivadavia (Argentina); Bruno, J A O [Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de QuImica Inorganica, AnalItica y QuImica FIsica, Pabellon 2, Ciudad Universitaria, 1428 Buenos Aires (Argentina); Barron, T H K [School of Chemistry, University of Bristol, Cantock' s Close, Bristol BS8 1TS (United Kingdom); Allan, N L [School of Chemistry, University of Bristol, Cantock' s Close, Bristol BS8 1TS (United Kingdom)

    2005-02-02

    There has been substantial renewed interest in negative thermal expansion following the discovery that cubic ZrW{sub 2}O{sub 8} contracts over a temperature range in excess of 1000 K. Substances of many different kinds show negative thermal expansion, especially at low temperatures. In this article we review the underlying thermodynamics, emphasizing the roles of thermal stress and elasticity. We also discuss vibrational and non-vibrational mechanisms operating on the atomic scale that are responsible for negative expansion, both isotropic and anisotropic, in a wide range of materials. (topical review)

  4. Parametric Assessment of Stress Development and Cracking in Internally Cured Restrained Mortars Experiencing Autogenous Deformations and Thermal Loading

    Directory of Open Access Journals (Sweden)

    Kambiz Raoufi

    2011-01-01

    Full Text Available A finite element model is used to examine how the properties of cementitious mortar are related to the stress development in the dual ring test. The results of this investigation are used to explain the thermal cracking behavior of mixtures containing prewetted lightweight aggregates (LWA by quantifying the contribution of several material properties individually. In addition to the beneficial effects of using the LWA as an internal curing agent to reduce the autogenous shrinkage of concrete, the LWA also helps to reduce the potential for thermal cracking due to a lower elastic modulus and increased stress relaxation. The rate of stress development, age of cracking, and magnitude of the temperature drop necessary to induce cracking in a dual ring specimen are dependent on a variety of factors, including the coefficient of thermal expansion of both the cementitious mortar and the restraining rings, elastic modulus of the mortar, creep effect of the mortar, and rate of thermal loading. Depending on the rate of cooling, cracking may or may not occur. The slowest rate of cooling (2.5∘C/h minimizes the effects of creep while cooling rates faster than 8∘C/h can produce a thermal gradient through the mortar cross-section that needs to be considered.

  5. Use of Guided Acoustic Waves to Assess the Effects of Thermal-Mechanical Cycling on Composite Stiffness

    Science.gov (United States)

    Seale, Michael D.; Madaras, Eric I.

    2000-01-01

    The introduction of new, advanced composite materials into aviation systems requires it thorough understanding of the long-term effects of combined thermal and mechanical loading. As part of a study to evaluate the effects of thermal-mechanical cycling, it guided acoustic (Lamb) wave measurement system was used to measure the bending and out-of-plane stiffness coefficients of composite laminates undergoing thermal-mechanical loading. The system uses a pulse/receive technique that excites an antisymmetric Lamb mode and measures the time-of-flight over a wide frequency range. Given the material density and plate thickness, the bending and out-of-plane shear stiffnesses are calculated from a reconstruction of the velocity dispersion curve. A series of 16 and 32-ply composite laminates were subjected to it thermal-mechanical loading profile in load frames equipped with special environmental chambers. The composite systems studied were it graphite fiber reinforced amorphous thermoplastic polyimide and it graphite fiber reinforced bismaleimide thermoset. The samples were exposed to both high and low temperature extremes its well as high and low strain profiles. The bending and out-of-plane stiffnesses for composite sample that have undergone over 6,000 cycles of thermal-mechanical loading are reported. The Lamb wave generated elastic stiffness results have shown decreases of up to 20% at 4,936 loading cycles for the graphite/thermoplastic samples and up to 64% at 4,706 loading cycles for the graphite/thermoset samples.

  6. AN ALGORITHM FOR THE ASSESSMENT OF SUBJECTIVE ADAPTIVE THERMAL COMFORT CONDITIONS BASED ON MULTI-AGENT SYSTEMS

    Directory of Open Access Journals (Sweden)

    C. Marino

    2011-10-01

    Full Text Available Thermal comfort conditions in the built environment are strictly related not only to the thermal and geometric building features and to air-conditioning systems, but also to the building destination, to its using profile and to the biological-metabolic-psychological characteristics of users. As a consequence, there is a strong claim for new models, both subjective and adaptive to the environment, in aparticular holistic vision of the problem, with regards to the novel tern user-plant-building system. In such a frame, through the paper the characterization of an algorithm aimed at subjective adaptive thermal comfort evaluations, enriching the one proposed by Fanger with an adaptive approach, is carried out using a Multi Agent System (MAS, based on Intelligent Agents, able to follow user’s needs and preferences in different contexts and expectations.

  7. Preliminary assessment of a mixture of capric and lauric acids for low-temperature thermal energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Dimaano, M.N.R. [University of Santo Tomas, Manila (Philippines). Research Center for the Natural Sciences; Escoto, A.D. [University of the Philippines, Quezon City (Philippines). Dept. of Chemical Engineering

    1998-05-01

    A mixture of capric and lauric acids was evaluated as a possible phase-change media suitable for Philippine low-temperature thermal-energy storage systems. The properties of different combinations of acids were verified against existing literature data with the use of a differential scanning calorimeter. Classical evaluation techniques were employed to determine the required thermodynamic, kinetic, and other physical properties. The accuracy of the set-up was determined and phase transitions were observed by performing a series of thermal cycles. To authenticate the long-term stability and reproducibility of the combination, 120 thermal cycles were carried out using a fabricated equilibrium cell. The observed lowest temperature averaged 11.63{sup o}C. The material remained physically stable. (author)

  8. Topic extraction from adverbial clauses

    Directory of Open Access Journals (Sweden)

    Carlos Rubio Alcalá

    2016-06-01

    Full Text Available This paper offers new data to support findings about Topic extraction from adverbial clauses. Since such clauses are strong islands, they should not allow extraction of any kind, but we show here that if the appropriate conditions are met, Topics of the CLLD kind in Romance can move out of them. We propose that two conditions must be met for such movement to be possible: the first is that the adverbial clause must have undergone topicalisation in the first place; the second is that the adverbial clause is inherently topical from a semantic viewpoint. Contrast with other language families (Germanic, Quechua and Japanese is provided and the semantic implications of the proposal are briefly discussed. Keywords: topicalisation; Clitic Left Dislocation; syntactic islands; adverbial clauses Este artículo ofrece nuevos datos sobre la extracción de Tópicos desde oraciones subordinadas adverbiales. Dado que dichas oraciones son islas fuertes, no deberían permitir extracción de ningún tipo, pero mostramos que si se dan las condiciones apropiadas, los Tópicos del tipo CLLD en lenguas románicas pueden desplazarse fuera de ellas. Proponemos que se deben cumplir dos condiciones para que ese movimiento sea posible: la primera es que la propia subordinada adverbial se haya topicalizado en primer lugar; la segunda es que la subordinada adverbial sea inherentemente un Tópico desde el punto de vista semántico. Proporcionamos también algunos contrastes con otras familias lingüísticas (germánica, quechua y japonés y se discuten brevemente las implicaciones semánticas de la propuesta. Palabras clave: topicalización; dislocación a la izquierda con clítico; islas sintácticas; oraciones adverbiales

  9. Potential theory—selected topics

    CERN Document Server

    Aikawwa, Hiroaki

    1996-01-01

    The first part of these lecture notes is an introduction to potential theory to prepare the reader for later parts, which can be used as the basis for a series of advanced lectures/seminars on potential theory/harmonic analysis. Topics covered in the book include minimal thinness, quasiadditivity of capacity, applications of singular integrals to potential theory, L(p)-capacity theory, fine limits of the Nagel-Stein boundary limit theorem and integrability of superharmonic functions. The notes are written for an audience familiar with the theory of integration, distributions and basic functional analysis.

  10. Topics in atomic collision theory

    CERN Document Server

    Geltman, Sydney; Brueckner, Keith A

    1969-01-01

    Topics in Atomic Collision Theory originated in a course of graduate lectures given at the University of Colorado and at University College in London. It is recommended for students in physics and related fields who are interested in the application of quantum scattering theory to low-energy atomic collision phenomena. No attention is given to the electromagnetic, nuclear, or elementary particle domains. The book is organized into three parts: static field scattering, electron-atom collisions, and atom-atom collisions. These are in the order of increasing physical complexity and hence necessar

  11. Experimental study of the surface thermal signature of gravity currents: application to the assessment of lava flow effusion rate

    Science.gov (United States)

    Garel, F.; Kaminski, E.; Tait, S.; Limare, A.

    2011-12-01

    During an effusive volcanic eruption, the crisis management is mainly based on the prediction of lava flows advance and its velocity. As the spreading of lava flows is mainly controlled by its rheology and the eruptive mass flux, the key question is how to evaluate them during the eruption (rather than afterwards.) A relationship between the heat flux lost by the lava at its surface and the eruption rate is likely to exist, based on the first-order argument that higher eruption rates should correspond to larger power radiated by a lava flow. The semi-empirical formula developed by Harris and co-workers (e.g. Harris et al., Bull. Volc. 2007) is currently used to estimate lava flow rate from satellite surveys yielding the surface temperatures and area of the lava flow field. However, this approach is derived from a static thermal budget of the lava flow and does not explicitly model the time-evolution of the surface thermal signal. Here we propose laboratory experiments and theoretical studies of the cooling of a viscous axisymmetric gravity current fed at constant flux rate. We first consider the isoviscous case, for which the spreading is well-know. The experiments using silicon oil and the theoretical model both reveal the establishment of a steady surface thermal structure after a transient time. The steady state is a balance between surface cooling and heat advection in the flow. The radiated heat flux in the steady regime, a few days for a basaltic lava flow, depends mainly on the effusion rate rather than on the viscosity. In this regime, one thermal survey of the radiated power could provide a consistent estimate of the flow rate if the external cooling conditions (wind) are reasonably well constrained. We continue to investigate the relationship between the thermal radiated heat flux and the effusion rate by using in the experiments fluids with temperature-dependent viscosity (glucose syrup) or undergoing solidification while cooling (PEG wax). We observe a

  12. Novel topical therapies for distal colitis

    Institute of Scientific and Technical Information of China (English)

    Ian; Craig; Lawrance

    2010-01-01

    Distal colitis(DC) can be effectively treated with topical 5ASA agents.Suppositories target the rectum while enemas can reliably reach the splenic flexure.Used in combination with oral 5ASAs,the control of the inflammation is even more effective.Unfortunately,resistant DC does occur and can be extremely challenging to manage.In these patients,the use of steroids,immunosuppressants and the anti-tumor necrosis factor α agents are often required.These,however,can be associated with systemic side effects and are not always effective.The investigation of new topical therapeutic agents is thus required as they are rarely associated with significant blood drug levels and side effects are infrequent.Some of the agents that have been proposed for use in resistant distal colitis include butyrate,cyclosporine and nicotine enemas as well as tacrolimus suppositories and tacrolimus,ecabet sodium,arsenic,lidocaine,rebamipide and Ridogrel enemas.Some of these agents have demonstrated impressive results but the majority of the agents have only been assessed in small open-labelled patient cohorts.Further work is thus required with the investigation of promising agents in the context of randomized double-blinded placebo controlled trials.This review aims to highlight those potentially effective therapies in the management of resistant distal colitis and to promote interest in furthering their investigation.

  13. Arrhenius Equation-Based Cell-Health Assessment: Application to Thermal Energy Management Design of a HEV NiMH Battery Pack

    Directory of Open Access Journals (Sweden)

    Fangyuan Chen

    2013-05-01

    Full Text Available This paper presents a model-based cell-health-conscious thermal energy management method. An Arrhenius equation-based mathematical model is firstly identified to quantify the effect of temperature on the cell lifetime of a Nickel Metal Hydride (NiMH battery pack. The cell aging datasets collected under multiple ambient temperatures are applied to extract the Arrhenius equation parameters. The model is then used as an assessment criterion and guidance for the thermal management design of battery packs. The feasibility and applicability of a pack structure with its cooling system, is then evaluated, and its design problems are studied by a computational fluid dynamics (CFD analysis. The performance and eligibility of the design method is validated by both CFD simulations and experiments.

  14. Influence of the Thermal Inertia in the European Simplified Procedures for the Assessment of Buildings’ Energy Performance

    Directory of Open Access Journals (Sweden)

    Luca Evangelisti

    2014-07-01

    Full Text Available This study aims to highlight the importance of thermal inertia in buildings. Nowadays, it is possible to use energy analysis software to simulate the building energy performance. Considering Italian standards, these analyses are based on the UNI TS 11300 that defines the procedures for the national implementation of the UNI EN ISO 13790. These standards require an energy analysis under steady-state condition, underestimating the thermal inertia of the building. In order to understand the inertial behavior of walls, a cubic Test-Cell was modelled through the dynamic calculation code TRNSYS and three different wall types were tested. Different stratigraphies, characterized by the same thermal transmittance value, composed by massive elements and insulating layers in different order, were simulated. Through TRNSYS, it was possible to define maximum surface temperatures and to calculate thermal lag between maximum values, both external and internal. Moreover, the attenuation between external surface temperatures and internal ones during summer (July was calculated. Finally, the comparison between Test-Cell’s annual energy demands, performed by using a commercial code based on the Italian standard UNITS 11300 and the dynamic code, TRNSYS, was carried out.

  15. Comparison of the efficacy and safety of topical clindamycin and 5% benzoyl peroxide with nadifloxacin cream and 5% benzoyl peroxide gel in the treatment of acne vulgaris and assessment of the effects of these treatments on quality of life

    Directory of Open Access Journals (Sweden)

    Aslıhan Kırkağaç

    2015-03-01

    Full Text Available Background and Design: Acne vulgaris is a multifactorial chronic inflammatory disase of the pilosebaceous unit. Topical antibiotics and anti-inflammatory treatment are used for mild and moderate acne. Clindamycin is frequently used for acne treatment, altough nadifloxacin is a relatively new agent. There are few studies evaluating nadifloxacin efficacy. It's impact on quality of life has not been determined previously. In this study, it is aimed to compare the effect of these two agents, and to evaluate the effect of these treatments on quality of life. Materials and Methods: Eighty patients with mild-moderate acne vulgaris were divided in two groups of 40 people that had no difference in terms of age, gender and acne severity. The combination of topical clindamycin and 5% benzoyl peroxide gel twice a day was given to group 1 for 12 weeks. The combination of nadifloxacin cream and 5% benzoyl peroxide gel twice a day was given to group 2 for 12 weeks. The number of the inflammatory and non-inflammatory lesions were recorded at baseline and on weeks 2, 4, 8, 12 and side effects were recorded and evaluated. Global improvement was evaluated separately by patients and doctor after the treatment. Before and after the treatment, the quality of life of the patients were evaluated with Skindex-29. Results: Both treatment group regimens were significantly effective on inflammatory and non-inflammatory lesions and were well tolerated by patients in terms of side effects. It was also observed that there was statistically significant recovery after treatment in terms of clinical severity and quality of life. There was not any statistically significant difference between two treatment methods in terms of effectiveness, side effect and quality of life. Conclusion: Nadifloxacin and 5% benzoyl peroxide combination is effective in the treatment and improvement of quality of life in acne patients.

  16. Enhanced Gender Recognition System Using an Improved Histogram of Oriented Gradient (HOG) Feature from Quality Assessment of Visible Light and Thermal Images of the Human Body.

    Science.gov (United States)

    Nguyen, Dat Tien; Park, Kang Ryoung

    2016-07-21

    With higher demand from users, surveillance systems are currently being designed to provide more information about the observed scene, such as the appearance of objects, types of objects, and other information extracted from detected objects. Although the recognition of gender of an observed human can be easily performed using human perception, it remains a difficult task when using computer vision system images. In this paper, we propose a new human gender recognition method that can be applied to surveillance systems based on quality assessment of human areas in visible light and thermal camera images. Our research is novel in the following two ways: First, we utilize the combination of visible light and thermal images of the human body for a recognition task based on quality assessment. We propose a quality measurement method to assess the quality of image regions so as to remove the effects of background regions in the recognition system. Second, by combining the features extracted using the histogram of oriented gradient (HOG) method and the measured qualities of image regions, we form a new image features, called the weighted HOG (wHOG), which is used for efficient gender recognition. Experimental results show that our method produces more accurate estimation results than the state-of-the-art recognition method that uses human body images.

  17. Topical Pain Relievers May Cause Burns

    Science.gov (United States)

    ... Consumers Consumer Updates Topical Pain Relievers May Cause Burns Share Tweet Linkedin Pin it More sharing options ... rare, have ranged from mild to severe chemical burns with use of such brand-name topical muscle ...

  18. Human-competitive automatic topic indexing

    CERN Document Server

    Medelyan, Olena

    2009-01-01

    Topic indexing is the task of identifying the main topics covered by a document. These are useful for many purposes: as subject headings in libraries, as keywords in academic publications and as tags on the web. Knowing a document’s topics helps people judge its relevance quickly. However, assigning topics manually is labor intensive. This thesis shows how to generate them automatically in a way that competes with human performance. Three kinds of indexing are investigated: term assignment, a task commonly performed by librarians, who select topics from a controlled vocabulary; tagging, a popular activity of web users, who choose topics freely; and a new method of keyphrase extraction, where topics are equated to Wikipedia article names. A general two-stage algorithm is introduced that first selects candidate topics and then ranks them by significance based on their properties. These properties draw on statistical, semantic, domain-specific and encyclopedic knowledge. They are combined using a machine learn...

  19. SAFE for PTSD: noncontact psychophysiological measure based on high-resolution thermal imaging to aid in PTSD diagnosis and assessment of treatment

    Science.gov (United States)

    Familoni, Babajide O.; Ma, Lein; Hutchinson, J. Andrew; Morgan, C. Andrew, III; Rasmusson, Ann; O'Kane, Barbara L.

    2012-06-01

    Post Traumatic Stress Disorder (PTSD) sometimes develops following exposure to very stressful or traumatic events such as motor vehicle accidents, rape, and war. It is arguably the signature injury of the conflicts in Iraq and Afghanistan. Previous studies have demonstrated that PTSD sufferers exhibit autonomic hyper-responsiveness to both neutral and trauma-related stimuli. In this study, we propose using high resolution thermal imaging of sweat-pores to obtain a noncontact, remote, and quantifiable measure of the sympathetic autonomic nervous reactivity to guide diagnosis, assess response to treatment, and tease out important cues to suicidality as a PTSD comorbidity.

  20. Environmental Assessment for the Operation of the Glass Melter Thermal Treatment Unit at the US Department of Energy`s Mound Plant, Miamisburg, Ohio

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The glass melter would thermally treat mixed waste (hazardous waste contaminated with radioactive constituents largely tritium, Pu-238, and/or Th-230) that was generated at the Mound Plant and is now in storage, by stabilizing the waste in glass blocks. Depending on the radiation level of the waste, the glass melter may operate for 1 to 6 years. Two onsite alternatives and seven offsite alternatives were considered. This environmental assessment indicates that the proposed action does not constitute a major Federal action significantly affecting the human environment according to NEPA, and therefore the finding of no significant impact is made, obviating the need for an environmental impact statement.

  1. Malta; Financial System Stability Assessment, including Reports on the Observance of Standards and Codes on the following topics: Monetary and Financial Policy Transparency, Banking Supervision, Securities Regulation, Insurance Regulation, Corporate Governance, and Payment Systems

    OpenAIRE

    International Monetary Fund

    2003-01-01

    The report provides the details of the Malta Financial Stability Assessment (MFSA). It defines its roles, responsibilities, and objectives for financial policies. It reviews the reports on the observance of standards and codes on monetary and financial policy transparency, banking supervision, securities regulation, insurance regulation, corporate governance, and payment systems. It assesses the macroeconomic environment and risks, soundness and vulnerabilities of the financial system, and al...

  2. Topics in Banach space theory

    CERN Document Server

    Albiac, Fernando

    2016-01-01

    This text provides the reader with the necessary technical tools and background to reach the frontiers of research without the introduction of too many extraneous concepts. Detailed and accessible proofs are included, as are a variety of exercises and problems. The two new chapters in this second edition are devoted to two topics of much current interest amongst functional analysts: Greedy approximation with respect to bases in Banach spaces and nonlinear geometry of Banach spaces. This new material is intended to present these two directions of research for their intrinsic importance within Banach space theory, and to motivate graduate students interested in learning more about them. This textbook assumes only a basic knowledge of functional analysis, giving the reader a self-contained overview of the ideas and techniques in the development of modern Banach space theory. Special emphasis is placed on the study of the classical Lebesgue spaces Lp (and their sequence space analogues) and spaces of continuous f...

  3. Topics in computational linear optimization

    DEFF Research Database (Denmark)

    Hultberg, Tim Helge

    2000-01-01

    of high quality solvers and the use of algebraic modelling systems to handle the communication between the modeller and the solver. This dissertation features four topics in computational linear optimization: A) automatic reformulation of mixed 0/1 linear programs, B) direct solution of sparse unsymmetric...... branch-and-bound algorithms depends heavily on the formulation of the problem. In seeking a better formulation, automatic reformulation employs a range of different techniques for obtaining an equivalent formulation of a given pure or mixed integer programming problem, such that the new formulation has...... a tighter LP-relaxation than the original formulation. The first paper surveys the use of automatic reformulation techniques for general mixed 0-1 linear programs. An implementation, Spiky, of a direct method for solving large sparse unsymmetric systems of linear equations is presented in the second paper...

  4. Topics in Open Topological Strings

    CERN Document Server

    Prudenziati, Andrea

    2010-01-01

    This thesis is based on some selected topics in open topological string theory which I have worked on during my Ph.D. It comprises an introductory part where I have focused on the points most needed for the later chapters, trading completeness for conciseness and clarity. Then, following [12], we discuss tadpole cancellation for topological strings where we mainly show how its implementation is needed for ensuring the same "odd" moduli decoupling encountered in the closed theory. Next we move to analyse how the open and closed effective field theories for the B model interact writing the complete Lagrangian. We first check it deriving some already known tree level amplitudes in term of target space quantities, and then we extend the recipe to new results; later we implement open closed duality from a target field theory perspective. This last subject is also analysed from a worldsheet point of view extending the analysis of [13]. Some ideas for future research are briefly reported.

  5. Synergetics introduction and advanced topics

    CERN Document Server

    Haken, Hermann

    2004-01-01

    This book is an often-requested reprint of two classic texts by H. Haken: "Synergetics. An Introduction" and "Advanced Synergetics". Synergetics, an interdisciplinary research program initiated by H. Haken in 1969, deals with the systematic and methodological approach to the rapidly growing field of complexity. Going well beyond qualitative analogies between complex systems in fields as diverse as physics, chemistry, biology, sociology and economics, Synergetics uses tools from theoretical physics and mathematics to construct an unifying framework within which quantitative descriptions of complex, self-organizing systems can be made. This may well explain the timelessness of H. Haken's original texts on this topic, which are now recognized as landmarks in the field of complex systems. They provide both the beginning graduate student and the seasoned researcher with solid knowledge of the basic concepts and mathematical tools. Moreover, they admirably convey the spirit of the pioneering work by the founder of ...

  6. Credibility improves topical blog post retrieval

    NARCIS (Netherlands)

    Weerkamp, W.; de Rijke, M.

    2008-01-01

    Topical blog post retrieval is the task of ranking blog posts with respect to their relevance for a given topic. To improve topical blog post retrieval we incorporate textual credibility indicators in the retrieval process. We consider two groups of indicators: post level (determined using informati

  7. Assessment of contamination of soil due to heavy metals around coal fired thermal power plants at Singrauli region of India.

    Science.gov (United States)

    Agrawal, Prashant; Mittal, Anugya; Prakash, Rajiv; Kumar, Manoj; Singh, T B; Tripathi, S K

    2010-08-01

    In the present study, an attempt was made to measure contamination of soil around four large coal-based Thermal Power Plants. The concentration of Cadmium, Lead, Arsenic and Nickel was estimated in all four directions from Thermal Power Plants. The soil in the study area was found to be contaminated to varying degrees from coal combustion byproducts. The soil drawn from various selected sites in each direction was largely contaminated by metals, predominantly higher within 2-4 km distance from Thermal Power Plant. Within 2-4 km, the mean maximum concentration of Cadmium, Lead, Arsenic and Nickel was 0.69, 13.69, 17.76, and 3.51 mg/kg, respectively. It was also observed that concentration was maximum in the prevalent wind direction. The concentration of Cadmium, Lead, Arsenic and Nickel was highest 0.69, 13.23, 17.29 and 3.56 mg/kg, respectively in west direction where wind was prevalent.

  8. Assessment of fatigue and fracture on a tee-junction of LMFBR piping under thermal striping phenomenon

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyeong Yeon; Kim, Jong Bum; Yoo, Bong [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1999-06-01

    This paper deals with the industrial problem of thermal striping damage on the French prototype fast breeder reactor, Phenix and it was studied in coordination with the research program of IAEA. The thermomechanical and fracture mechanics evaluation procedure of thermal striping damage on the tee-junction of the secondary piping using Green's function method and standard FEM is presented. The thermohydraulic (T/H) loading condition used in the present analysis is the random type thermal loads computed by T/H analysis on the turbulent mixing of the two flows with different temperatures. The thermomechanical fatigue damage was evaluated according to ASME code section III subsection NH. The results of the fatigue analysis showed that fatigue failure would occur at the welded joint showed that the crack would be initiated at an early stage in the operation. It took 42,698.9 hours for the crack to propagate up to 5 mm along the thickness direction. After then, however, the instability analysis, using tearing modulus, showed that the crack would be arrested, which was in agreement with the actual observation of the crack. An efficient analysis procedure using Green's function approach for the crack propagation problem under random type load was proposed in this study. The analysis results showed good agreement with those of the practical observation. (author). 7 refs., 12 figs., 1 tab.

  9. Thermal Analysis by Structural Characterization as a Method for Assessing Heterogeneity in Complex Solid Pharmaceutical Dosage Forms.

    Science.gov (United States)

    Alhijjaj, Muqdad; Reading, Mike; Belton, Peter; Qi, Sheng

    2015-11-03

    Characterizing inter- and intrasample heterogeneity of solid and semisolid pharmaceutical products is important both for rational design of dosage forms and subsequent quality control during manufacture; however, most pharmaceutical products are multicomponent formulations that are challenging in this regard. Thermal analysis, in particular differential scanning calorimetry, is commonly used to obtain structural information, such as degree of crystallinity, or identify the presence of a particular polymorph, but the results are an average over the whole sample; it cannot directly provide information about the spatial distribution of phases. This study demonstrates the use of a new thermo-optical technique, thermal analysis by structural characterization (TASC), that can provide spatially resolved information on thermal transitions by applying a novel algorithm to images acquired by hot stage microscopy. We determined that TASC can be a low cost, relatively rapid method of characterizing heterogeneity and other aspects of structure. In the examples studied, it was found that high heating rates enabled screening times of 3-5 min per sample. In addition, this study demonstrated the higher sensitivity of TASC for detecting the metastable form of polyethylene glycol (PEG) compared to conventional differential scanning calorimetry (DSC). This preliminary work suggests that TASC will be a worthwhile additional tool for characterizing a broad range of materials.

  10. Thermal Stress Assessment for Transient Liquid-Phase Bonded Si Chips in High-Power Modules Using Experimental and Numerical Methods

    Science.gov (United States)

    Lis, Adrian; Kicin, Slavo; Brem, Franziska; Leinenbach, Christian

    2016-11-01

    The potential of transient liquid-phase (TLP) bonding for chip packaging applications has been evaluated, focusing on three interlayer arrangements (Ag-Sn-Ag, Ni-Sn-Ni, and Ag-Sn-Ni). Shear tests on TLP-bonded components provided the interlayer-dependent mechanical strength as well as failure mode and position. Critical local stresses, i.e., failure criteria, within the intermetallic compound (IMC) layer were derived by replicating the shear test conditions with finite-element methods. The missing coefficient of thermal expansion for Ag3Sn IMC was obtained by producing small IMC bulk samples and subjecting them to dilatometric measurements. The experimental results were implemented into a finite-element model of a representative power module architecture to provide first predictions on thermally induced residual stresses that could be classified into fail/safe, as successfully validated by TLP chip bonding experiments. A numerical parameter study then assessed thermal stresses, including failure prediction and design optimization for TLP-bonded Si chips, considering the influence of process temperature, service conditions, TLP interlayer system, and metallization layers within the TLP joint. The presented procedure serves as a guideline to choose an appropriate TLP interlayer system for predefined boundary conditions, or vice versa.

  11. Thermal Stress Assessment for Transient Liquid-Phase Bonded Si Chips in High-Power Modules Using Experimental and Numerical Methods

    Science.gov (United States)

    Lis, Adrian; Kicin, Slavo; Brem, Franziska; Leinenbach, Christian

    2017-02-01

    The potential of transient liquid-phase (TLP) bonding for chip packaging applications has been evaluated, focusing on three interlayer arrangements (Ag-Sn-Ag, Ni-Sn-Ni, and Ag-Sn-Ni). Shear tests on TLP-bonded components provided the interlayer-dependent mechanical strength as well as failure mode and position. Critical local stresses, i.e., failure criteria, within the intermetallic compound (IMC) layer were derived by replicating the shear test conditions with finite-element methods. The missing coefficient of thermal expansion for Ag3Sn IMC was obtained by producing small IMC bulk samples and subjecting them to dilatometric measurements. The experimental results were implemented into a finite-element model of a representative power module architecture to provide first predictions on thermally induced residual stresses that could be classified into fail/safe, as successfully validated by TLP chip bonding experiments. A numerical parameter study then assessed thermal stresses, including failure prediction and design optimization for TLP-bonded Si chips, considering the influence of process temperature, service conditions, TLP interlayer system, and metallization layers within the TLP joint. The presented procedure serves as a guideline to choose an appropriate TLP interlayer system for predefined boundary conditions, or vice versa.

  12. Multilingual Topic Models for Unaligned Text

    CERN Document Server

    Boyd-Graber, Jordan

    2012-01-01

    We develop the multilingual topic model for unaligned text (MuTo), a probabilistic model of text that is designed to analyze corpora composed of documents in two languages. From these documents, MuTo uses stochastic EM to simultaneously discover both a matching between the languages and multilingual latent topics. We demonstrate that MuTo is able to find shared topics on real-world multilingual corpora, successfully pairing related documents across languages. MuTo provides a new framework for creating multilingual topic models without needing carefully curated parallel corpora and allows applications built using the topic model formalism to be applied to a much wider class of corpora.

  13. Clitoral hemodynamic changes after a topical application of alprostadil.

    Science.gov (United States)

    Becher, E F; Bechara, A; Casabe, A

    2001-01-01

    We performed duplex ultrasonography of the clitoris to assess the local hemodynamic changes after a topical application of alprostadil. Color duplex ultrasonography was used to evaluate 18 women before and after the application of 1 g of 0.2% alprostadil gel. The peak systolic velocity and end diastolic velocity showed a statistically significant difference after the application. All women showed labial and clitoral engorgement, 72% reported a pleasant sensation of warmth, and no systemic side effects were found. These findings are similar to the values reported after sexual stimulation, indicating that topical vasoactive drugs might help in the differential diagnosis of the vascular component of female sexual dysfunction.

  14. Topical Day on Site Remediation

    Energy Technology Data Exchange (ETDEWEB)

    Vandenhove, H. [ed.

    1996-09-18

    Ongoing activities at the Belgian Nuclear Research Centre relating to site remediation and restoration are summarized. Special attention has been paid to the different phases of remediation including characterization, impact assessment, evaluation of remediation actions, and execution of remediation actions.

  15. The degree of hydration assessment of blended cement pastes by differential thermal and thermogravimetric analysis. Morphological evolution of the solid phases

    Energy Technology Data Exchange (ETDEWEB)

    Monteagudo, S.M., E-mail: sm.monteagudo@alumnos.upm.es [Departamento de Ingeniería Civil: Construcción, Escuela Técnica Superior de Ingenieros de Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Moragues, A., E-mail: amoragues@caminos.upm.es [Departamento de Ingeniería Civil: Construcción, Escuela Técnica Superior de Ingenieros de Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Gálvez, J.C., E-mail: jaime.galvez@upm.es [Departamento de Ingeniería Civil: Construcción, Escuela Técnica Superior de Ingenieros de Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Madrid 28040 (Spain); Casati, M.J., E-mail: mariajesus.casati@upm.es [Departamento de Vehículos Aeroespaciales, Escuela de Ingeniería Aeronáutica, Universidad Politécnica de Madrid (Spain); Reyes, E., E-mail: encarnacion.reyes@upm.es [Departamento de Ingeniería Civil: Construcción, Escuela Técnica Superior de Ingenieros de Caminos, Canales y Puertos, Universidad Politécnica de Madrid, Madrid 28040 (Spain)

    2014-09-20

    Highlights: • A proposal of hydration degree calculation for blended cement pastes is presented. • The method is based both on the contributions of various authors and on DTA–TG results. • Paste and mortar specimens with BFS, FA and SF mineral admixtures were used. • The evaluation of CH gives information on hydration and pozzolanic reactions. • The assessment of α provides an insight into future strength evolution. - Abstract: The degree of hydration assessment of cement paste from differential thermal and thermogravimetric analysis data has been performed by several authors that have offered a number of proposals for technical application to blended cements. In this paper, two calculation methods are studied in detail. Then, a proposal of the degree of hydration calculation for blended cements, based on the analysis of experimental results of DTA–TG, is presented. The proposed method combines the contributions of the authors and allows straightforward calculation of the degree of hydration from the experimental results. Validation of the methodology was performed by macroscopic and microstructural tests through paste and mortar specimens with blast furnace slag, flying ash and silica fume mineral admixtures bei(g)ng used. Tests of scanning electron microscopy with an energy dispersive analyser on paste specimens, and of mechanical strength on mortar specimens with the same percentages of substitution, were performed. They showed good agreement with the information derived from the differential thermal and thermogravimetric analysis data.

  16. Identifying Topics in Microblogs Using Wikipedia.

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  17. Using High-Resolution Hyperspectral and Thermal Airborne Imagery to Assess Physiological Condition in the Context of Wheat Phenotyping

    Directory of Open Access Journals (Sweden)

    Victoria Gonzalez-Dugo

    2015-10-01

    Full Text Available There is a growing need for developing high-throughput tools for crop phenotyping that would increase the rate of genetic improvement. In most cases, the indicators used for this purpose are related with canopy structure (often acquired with RGB cameras and multispectral sensors allowing the calculation of NDVI, but using approaches related with the crop physiology are rare. High-resolution hyperspectral remote sensing imagery provides optical indices related to physiological condition through the quantification of photosynthetic pigment and chlorophyll fluorescence emission. This study demonstrates the use of narrow-band indicators of stress as a potential tool for phenotyping under rainfed conditions using two airborne datasets acquired over a wheat experiment with 150 plots comprising two species and 50 varieties (bread and durum wheat. The flights were performed at the early stem elongation stage and during the milking stage. Physiological measurements made at the time of flights demonstrated that the second flight was made during the terminal stress, known to largely determine final yield under rainfed conditions. The hyperspectral imagery enabled the extraction of thermal, radiance, and reflectance spectra from 260 spectral bands from each plot for the calculation of indices related to photosynthetic pigment absorption in the visible and red-edge regions, the quantification of chlorophyll fluorescence emission, as well as structural indices related to canopy structure. Under the conditions of this study, the structural indices (i.e., NDVI did not show a good performance at predicting yield, probably because of the large effects of terminal water stress. Thermal indices, indices related to chlorophyll fluorescence (calculated using the FLD method, and carotenoids pigment indices (PRI and CAR demonstrated to be better suited for screening complex traits such as crop yield. The study concludes that the indicators derived from high

  18. Topics in Number Theory Conference

    CERN Document Server

    Andrews, George; Ono, Ken

    1999-01-01

    From July 31 through August 3,1997, the Pennsylvania State University hosted the Topics in Number Theory Conference. The conference was organized by Ken Ono and myself. By writing the preface, I am afforded the opportunity to express my gratitude to Ken for beng the inspiring and driving force behind the whole conference. Without his energy, enthusiasm and skill the entire event would never have occurred. We are extremely grateful to the sponsors of the conference: The National Sci­ ence Foundation, The Penn State Conference Center and the Penn State Depart­ ment of Mathematics. The object in this conference was to provide a variety of presentations giving a current picture of recent, significant work in number theory. There were eight plenary lectures: H. Darmon (McGill University), "Non-vanishing of L-functions and their derivatives modulo p. " A. Granville (University of Georgia), "Mean values of multiplicative functions. " C. Pomerance (University of Georgia), "Recent results in primality testing. " C. ...

  19. Decision Point 1 Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Yablonsky, Al; Barsoumian, Shant; Legere, David

    2013-05-01

    This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

  20. Understanding topics and sentiment in an online cancer survivor community.

    Science.gov (United States)

    Portier, Kenneth; Greer, Greta E; Rokach, Lior; Ofek, Nir; Wang, Yafei; Biyani, Prakhar; Yu, Mo; Banerjee, Siddhartha; Zhao, Kang; Mitra, Prasenjit; Yen, John

    2013-12-01

    Online cancer communities help members support one another, provide new perspectives about living with cancer, normalize experiences, and reduce isolation. The American Cancer Society's 166000-member Cancer Survivors Network (CSN) is the largest online peer support community for cancer patients, survivors, and caregivers. Sentiment analysis and topic modeling were applied to CSN breast and colorectal cancer discussion posts from 2005 to 2010 to examine how sentiment change of thread initiators, a measure of social support, varies by discussion topic. The support provided in CSN is highest for medical, lifestyle, and treatment issues. Threads related to 1) treatments and side effects, surgery, mastectomy and reconstruction, and decision making for breast cancer, 2) lung scans, and 3) treatment drugs in colon cancer initiate with high negative sentiment and produce high average sentiment change. Using text mining tools to assess sentiment, sentiment change, and thread topics provides new insights that community managers can use to facilitate member interactions and enhance support outcomes.

  1. Assessment of the origin and geothermal potential of the thermal waters by hydro-isotope geochemistry: Eskisehir province, Turkey.

    Science.gov (United States)

    Yuce, Galip; Italiano, Francesco; Yasin, Didem; Taskiran, Lutfi; Gulbay, Ahmet Hilmi

    2017-05-01

    The thermal fluids vented over Eskisehir province have been investigated for their origin and to estimate the geothermal potential of the area. Thermal waters as well as bubbling and dissolved gases were collected and analysed for their chemical and isotopic features. Their isotopic composition varies in the range from -11.5 to -7.7 ‰ for δ(18)O, -84 and -57 ‰ for δ(2)H, and 0-7.2 TU for tritium. The gases (bubbling and dissolved) are mostly N2-dominated with a significant amount of CO2. The helium isotopic ratios are in the range of 0.2-0.66 R/Rac, indicate remarkable mantle-He contribution ranging between 2 and 10 % in the whole study area. Considering the estimated geothermal gradient about three times higher than the normal gradient, and the reservoir temperatures estimated to be between 50 and 100 °C using quartz and chalcedony geothermometers, a circulation model was built where possible mixing with shallow waters cool down the uprising geothermal fluids.

  2. Recent Advances In Topical Therapy In Dermatology

    Directory of Open Access Journals (Sweden)

    Mohan Thappa Devinder

    2003-01-01

    Full Text Available With changing times various newer topical agents are introduced in the field of dermatology. Tacrolimus and pimecrolimus are immunisuppressants, which are effective topically and are tried in the management of atopic dermatitis as well as other disorders including allergic contact dermatitis, atrophic lichen planus, pyoderma gangrenosum. Imiquimod, an immune response modifier, is presently in use for genital warts but has potentials as anti- tumour agent and in various other dermatological conditions when used topically. Tazarotene is a newer addition to the list of topical reginoids, which is effective in psoriasis and has better effect in combination with calcipotriene, phototherapy and topical costicosteroids. Tazarotene and adapelene are also effective in inflammatory acne. Calcipotriol, a vitamin D analogue has been introduced as a topical agent in the treatment of psoriasis. Steroid components are also developed recently which will be devoid of the side effects but having adequate anti-inflammatory effect. Topical photodynamic therapy has also a wide range of use in dermatology. Newer topical agents including cidofovir, capsaicin, topical sensitizers, topical antifungal agents for onychomycosis are also of use in clinical practice. Other promising developments include skin substitutes and growth factors for wound care.

  3. Redundancy-aware topic modeling for patient record notes.

    Directory of Open Access Journals (Sweden)

    Raphael Cohen

    Full Text Available The clinical notes in a given patient record contain much redundancy, in large part due to clinicians' documentation habit of copying from previous notes in the record and pasting into a new note. Previous work has shown that this redundancy has a negative impact on the quality of text mining and topic modeling in particular. In this paper we describe a novel variant of Latent Dirichlet Allocation (LDA topic modeling, Red-LDA, which takes into account the inherent redundancy of patient records when modeling content of clinical notes. To assess the value of Red-LDA, we experiment with three baselines and our novel redundancy-aware topic modeling method: given a large collection of patient records, (i apply vanilla LDA to all documents in all input records; (ii identify and remove all redundancy by chosing a single representative document for each record as input to LDA; (iii identify and remove all redundant paragraphs in each record, leaving partial, non-redundant documents as input to LDA; and (iv apply Red-LDA to all documents in all input records. Both quantitative evaluation carried out through log-likelihood on held-out data and topic coherence of produced topics and qualitative assessment of topics carried out by physicians show that Red-LDA produces superior models to all three baseline strategies. This research contributes to the emerging field of understanding the characteristics of the electronic health record and how to account for them in the framework of data mining. The code for the two redundancy-elimination baselines and Red-LDA is made publicly available to the community.

  4. Pentyl Gallate Nanoemulsions as Potential Topical Treatment of Herpes Labialis.

    Science.gov (United States)

    Kelmann, Regina G; Colombo, Mariana; De Araújo Lopes, Sávia Caldeira; Nunes, Ricardo J; Pistore, Morgana; Dall Agnol, Daniele; Rigotto, Caroline; Silva, Izabella Thais; Roman, Silvane S; Teixeira, Helder F; Oliveira Simões, Cláudia M; Koester, Letícia S

    2016-07-01

    Previous studies have demonstrated the antiherpes activity of pentyl gallate (PG), suggesting that it could be a promising candidate for the topical treatment of human herpes labialis. PG low aqueous solubility represents a major drawback to its incorporation in topical dosage forms. Hence, the feasibility of incorporating PG into nanoemulsions, the ability to penetrate the skin, to inhibit herpes simplex virus (HSV)-1 replication, and to cause dermal sensitization or toxicity were evaluated. Oil/water nanoemulsions containing 0.5% PG were prepared by spontaneous emulsification. The in vitro PG distribution into porcine ear skin after topical application of nanoemulsions was assessed, and the in vitro antiviral activity against HSV-1 replication was evaluated. Acute dermal toxicity and risk of dermal sensitization were evaluated in rat model. Nanoemulsions presented nanometric particle size (from 124.8 to 143.7 nm), high zeta potential (from -50.1 to -66.1 mV), loading efficiency above 99%, and adequate stability during 12 months. All formulations presented anti-HSV-1 activity. PG was able to reach deeper into the dermis more efficiently from the nanoemulsion F4. This formulation as well as PG were considered safe for topical use. Nanoemulsions seem to be a safe and effective approach for topically delivering PG in the treatment of human herpes labialis infection.

  5. Selected topics of fluid mechanics

    Science.gov (United States)

    Kindsvater, Carl E.

    1958-01-01

    the Euler, Froude, Reynolds, Weber, and Cauchy numbers are defined as essential tools for interpreting and using experimental data. The derivations of the energy and momentum equations are treated in detail. One-dimensional equations for steady nonuniform flow are developed, and the restrictions applicable to the equations are emphasized. Conditions of uniform and gradually varied flow are discussed, and the origin of the Chezy equation is examined in relation to both the energy and the momentum equations. The inadequacy of all uniform-flow equations as a means of describing gradually varied flow is explained. Thus, one of the definitive problems of river hydraulics is analyzed in the light of present knowledge. This report is the outgrowth of a series of short schools conducted during the spring and summer of 1953 for engineers of the Surface Water Branch, Water Resources Division, U. S. Geological Survey. The topics considered are essentially the same as the topics selected for inclusion in the schools. However, in order that they might serve better as a guide and outline for informal study, the arrangement of the writer's original lecture notes has been considerably altered. The purpose of the report, like the purpose of the schools which inspired it, is to build a simple but strong framework of the fundamentals of fluid mechanics. It is believed that this framework is capable of supporting a detailed analysis of most of the practical problems met by the engineers of the Geological Survey. It is hoped that the least accomplishment of this work will be to inspire the reader with the confidence and desire to read more of the recent and current technical literature of modern fluid mechanics.

  6. A One-year, Short-Stay Crewed Mars Mission Using Bimodal Nuclear Thermal Electric Propulsion (BNTEP) - A Preliminary Assessment

    Science.gov (United States)

    Burke, Laura A.; Borowski, Stanley K.; McCurdy, David R.; Packard, Thomas W.

    2013-01-01

    A crewed mission to Mars poses a signi cant challenge in dealing with the physiolog- ical issues that arise with the crew being exposed to a near zero-gravity environment as well as signi cant solar and galactic radiation for such a long duration. While long sur- face stay missions exceeding 500 days are the ultimate goal for human Mars exploration, short round trip, short surface stay missions could be an important intermediate step that would allow NASA to demonstrate technology as well as study the physiological e ects on the crew. However, for a 1-year round trip mission, the outbound and inbound hy- perbolic velocity at Earth and Mars can be very large resulting in a signi cant propellant requirement for a high thrust system like Nuclear Thermal Propulsion (NTP). Similarly, a low thrust Nuclear Electric Propulsion (NEP) system requires high electrical power lev- els (10 megawatts electric (MWe) or more), plus advanced power conversion technology to achieve the lower speci c mass values needed for such a mission. A Bimodal Nuclear Thermal Electric Propulsion (BNTEP) system is examined here that uses three high thrust Bimodal Nuclear Thermal Rocket (BNTR) engines allowing short departure and capture maneuvers. The engines also generate electrical power that drives a low thrust Electric Propulsion (EP) system used for ecient interplanetary transit. This combined system can help reduce the total launch mass, system and operational requirements that would otherwise be required for equivalent NEP or Solar Electric Propulsion (SEP) mission. The BNTEP system is a hybrid propulsion concept where the BNTR reactors operate in two separate modes. During high-thrust mode operation, each BNTR provides 10's of kilo- Newtons of thrust at reasonably high speci c impulse (Isp) of 900 seconds for impulsive trans-planetary injection and orbital insertion maneuvers. When in power generation / EP mode, the BNTR reactors are coupled to a Brayton power conversion system allowing each

  7. A One-year, Short-Stay Crewed Mars Mission Using Bimodal Nuclear Thermal Electric Propulsion (BNTEP) - A Preliminary Assessment

    Science.gov (United States)

    Burke, Laura M.; Borowski, Stanley K.; McCurdy, David R.; Packard, Thomas W.

    2013-01-01

    A crewed mission to Mars poses a significant challenge in dealing with the physiological issues that arise with the crew being exposed to a near zero-gravity environment as well as significant solar and galactic radiation for such a long duration. While long surface stay missions exceeding 500 days are the ultimate goal for human Mars exploration, short round trip, short surface stay missions could be an important intermediate step that would allow NASA to demonstrate technology as well as study the physiological effects on the crew. However, for a 1-year round trip mission, the outbound and inbound hyperbolic velocity at Earth and Mars can be very large resulting in a significant propellant requirement for a high thrust system like Nuclear Thermal Propulsion (NTP). Similarly, a low thrust Nuclear Electric Propulsion (NEP) system requires high electrical power levels (10 megawatts electric (MWe) or more), plus advanced power conversion technology to achieve the lower specific mass values needed for such a mission. A Bimodal Nuclear Thermal Electric Propulsion (BNTEP) system is examined here that uses three high thrust Bimodal Nuclear Thermal Rocket (BNTR) engines allowing short departure and capture maneuvers. The engines also generate electrical power that drives a low thrust Electric Propulsion (EP) system used for efficient interplanetary transit. This combined system can help reduce the total launch mass, system and operational requirements that would otherwise be required for equivalent NEP or Solar Electric Propulsion (SEP) mission. The BNTEP system is a hybrid propulsion concept where the BNTR reactors operate in two separate modes. During high-thrust mode operation, each BNTR provides 10's of kilo-Newtons of thrust at reasonably high specific impulse (Isp) of 900 seconds for impulsive transplanetary injection and orbital insertion maneuvers. When in power generation/EP mode, the BNTR reactors are coupled to a Brayton power conversion system allowing each

  8. Intraoperative application of thermal camera for the assessment of during surgical resection or biopsy of human's brain tumors

    Science.gov (United States)

    Kastek, M.; Piatkowski, T.; Polakowski, H.; Kaczmarska, K.; Czernicki, Z.; Bogucki, J.; Zebala, M.

    2014-05-01

    Motivation to undertake research on brain surface temperature in clinical practice is based on a strong conviction that the enormous progress in thermal imaging techniques and camera design has a great application potential. Intraoperative imaging of pathological changes and functionally important areas of the brain is not yet fully resolved in neurosurgery and remains a challenge. A study of temperature changes across cerebral cortex was performed for five patients with brain tumors (previously diagnosed using magnetic resonance or computed tomography) during surgical resection or biopsy of tumors. Taking into account their origin and histology the tumors can be divided into the following types: gliomas, with different degrees of malignancy (G2 to G4), with different metabolic activity and various temperatures depending on the malignancy level (3 patients), hypervascular tumor associated with meninges (meningioma), metastatic tumor - lung cancer with a large cyst and noticeable edema. In the case of metastatic tumor with large edema and a liquid-filled space different temperature of a cerebral cortex were recorded depending on metabolic activity. Measurements have shown that the temperature on the surface of the cyst was on average 2.6 K below the temperature of surrounding areas. It has been also observed that during devascularization of a tumor, i.e. cutting off its blood vessels, the tumor temperature lowers significantly in spite of using bipolar coagulation, which causes additional heat emission in the tissue. The results of the measurements taken intra-operatively confirm the capability of a thermal camera to perform noninvasive temperature monitoring of a cerebral cortex. As expected surface temperature of tumors is different from surface temperature of tissues free from pathological changes. The magnitude of this difference depends on histology and the origin of the tumor. These conclusions lead to taking on further experimental research, implementation

  9. Topical ocular delivery of NSAIDs.

    Science.gov (United States)

    Ahuja, Munish; Dhake, Avinash S; Sharma, Surendra K; Majumdar, Dipak K

    2008-06-01

    In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak acids with pKa mostly between 3.5 and 4.5, and are poorly soluble in water. Aqueous ophthalmic solutions of NSAIDs have been made using sodium, potassium, tromethamine and lysine salts or complexing with cyclodextrins/solubilizer. Ocular penetration of NSAID demands an acidic ophthalmic solution where cyclodextrin could prevent precipitation of drug and minimize its ocular irritation potential. The incompatibility of NSAID with benzalkonium chloride is avoided by using polysorbate 80, cyclodextrins or tromethamine. Lysine salts and alpha-tocopheryl polyethylene glycol succinate disrupt corneal integrity, and their use requires caution. Thus a nonirritating ophthalmic solution of NSAID could be formulated by dissolving an appropriate water-soluble salt, in the presence of cyclodextrin or tromethamine (if needed) in mildly acidified purified water (if stability permits) with or without benzalkonium chloride and polyvinyl alcohol. Amide prodrugs met with mixed success due to incomplete intraocular hydrolysis. Suspension and ocular inserts appear irritating to the inflamed eye. Oil drop may be a suitable option for insoluble drugs and ointment may be used for sustained effect. Recent studies showed that the use of colloidal nanoparticle formulations and the potent COX 2 inhibitor bromfenac may enhance NSAID efficacy in eye preparations.

  10. Assessment of Models of Galactic Thermal Dust Emission Using COBE/FIRAS and COBE/DIRBE Observations

    CERN Document Server

    Odegard, N; Chuss, D T; Miller, N J

    2016-01-01

    Accurate modeling of the spectrum of thermal dust emission at millimeter wavelengths is important for improving the accuracy of foreground subtraction for CMB measurements, for improving the accuracy with which the contributions of different foreground emission components can be determined, and for improving our understanding of dust composition and dust physics. We fit four models of dust emission to high Galactic latitude COBE/FIRAS and COBE/DIRBE observations from 3 millimeters to 100 microns and compare the quality of the fits. We consider the two-level systems model because it provides a physically motivated explanation for the observed long wavelength flattening of the dust spectrum and the anticorrelation between emissivity index and dust temperature. We consider the model of Finkbeiner, Davis, and Schlegel because it has been widely used for CMB studies, and the generalized version of this model recently applied to Planck data by Meisner and Finkbeiner. For comparison we have also fit a phenomenologic...

  11. Usage-Oriented Topic Maps Building Approach

    Science.gov (United States)

    Ellouze, Nebrasse; Lammari, Nadira; Métais, Elisabeth; Ben Ahmed, Mohamed

    In this paper, we present a collaborative and incremental construction approach of multilingual Topic Maps based on enrichment and merging techniques. In recent years, several Topic Map building approaches have been proposed endowed with different characteristics. Generally, they are dedicated to particular data types like text, semi-structured data, relational data, etc. We note also that most of these approaches take as input monolingual documents to build the Topic Map. The problem is that the large majority of resources available today are written in various languages, and these resources could be relevant even to non-native speakers. Thus, our work is driven towards a collaborative and incremental method for Topic Map construction from textual documents available in different languages. To enrich the Topic Map, we take as input a domain thesaurus and we propose also to explore the Topic Map usage which means available potential questions related to the source documents.

  12. Assessing the Seasonal Variability of Thermal Stresses during the Last Half Century in Some Climatic Zones of Iran

    Directory of Open Access Journals (Sweden)

    Gh Fallah Ghalhari

    2016-09-01

    Full Text Available Background and Objectives: Nowadays, indicators related to human physiology have special roles in human bioclimatic and environmental studies. One of these indices is Physiological Equivalent Temperature (PET. In the present study, trends of physiological equivalent temperature index over the past half century, which is the foundation of plans, especially in the field of health and environment, were evaluated in four climatic regions of Iran (Mashhad, Rasht, Esfahan, Tabriz and Bandar Abbas. Material and methods: In this study, the data required to calculate the heat stress in the daily scale for 50 years during 1961-2010 were obtained from Iranian Meteorological Organization. Then, PET index at the daily scale was calculated and values greater than 35°C were identified for warm periods of the year. In the next step, the seasonal trends were analyzed by Mann-Kendall test. Results: Changes in the frequency of days with heat stress in stations of Mashhad, Isfahan, and Tabriz have been rising during spring and summer. In other words, the greatest amount of positive change has occurred over the long-term average in these cities. The highest frequency of hot days was observed in Rasht and Bandar Abbas stations. The main reason for this subject has to do with how adjacent they were to the sea and the high rate of evaporation in such areas. Conclusion: The 1980s-1990s have been allocated as the most days of hot stress. Upward trend of thermal stress occurring in the studied stations has increased the attention to the problem of heat stress and disease (thermal attack, fainting, muscle cramps from the field of planning and management of the crisis.

  13. Convective heat transfer from a nude body under calm conditions: assessment of the effects of walking with a thermal manikin.

    Science.gov (United States)

    Oliveira, A Virgílio M; Gaspar, Adélio R; Francisco, Sara C; Quintela, Divo A

    2012-03-01

    The present experimental work is dedicated to the analysis of the effect of walking on the thermal insulation of the air layer (I (a)) and on the convective heat transfer coefficients (h (conv)) of the human body. Beyond the standing static posture, three step rates were considered: 20, 30 and 45 steps/min. This corresponds to walking speeds of approximately 0.23, 0.34 and 0.51 m/s, respectively. The experiments took place in a climate chamber with an articulated thermal manikin with 16 independent parts. The indoor environment was controlled through the inner wall temperatures since the objective of the tests was restricted to the influence of the walking movements under calm conditions. Five set points were selected: 10, 15, 20, 25 and 30°C, and the operative temperature within the test chamber varied between 11.9 and 29.6°C. The highest and lowest I ( a ) values obtained were equal to 0.87 and 0.71 clo, respectively, and the reduction in insulation due to walking ranged between 9.8 and 11.5%. The convective coefficients (h (conv)) for the whole body and for the different body segments were also determined for each step rate. In the case of the whole body, for the standing static reference posture, the mean value of h (conv) was equal to 3.3 W/m(2)°C and a correlation [Nu = Nu(Gr)] for natural convection is also presented in good agreement with previous results. For the other postures, the values of h (conv) were equal to 3.7, 3.9 and 4.2 W/m(2)°C, respectively for 20, 30 and 45 steps/min.

  14. Tracking topic birth and death in LDA.

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Andrew T.; Robinson, David Gerald

    2011-09-01

    Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

  15. Using thermal imaging to assess the effect of classical massage on selected physiological parameters of upper limbs

    Directory of Open Access Journals (Sweden)

    Boguszewski Dariusz

    2014-12-01

    Full Text Available Study aim: the aim of this study was to assess the relationship between classical sport massage of the hand and the forearm and the surface temperature of upper limb muscles, and between hand grip strength and the range of motion in the radiocarpal joint.

  16. Thermal energy storage

    Science.gov (United States)

    1980-01-01

    The planning and implementation of activities associated with lead center management role and the technical accomplishments pertaining to high temperature thermal energy storage subsystems are described. Major elements reported are: (1) program definition and assessment; (2) research and technology development; (3) industrial storage applications; (4) solar thermal power storage applications; and (5) building heating and cooling applications.

  17. The treatment of rosacea with topical ivermectin.

    Science.gov (United States)

    Ali, S T; Alinia, H; Feldman, S R

    2015-04-01

    The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated.

  18. Criteria for sustainable buildings: Assessment of indoor thermal environment - a contribution to the discussion; Kriterien des nachhaltigen Bauens: Bewertung des thermischen Raumklimas - ein Diskussionsbeitrag

    Energy Technology Data Exchange (ETDEWEB)

    Hellwig, Runa T.; Steiger, Simone; Hauser, Gerd; Holm, Andreas; Sedlbauer, Klaus [Fraunhofer-Institut fuer Bauphysik, Valley (Germany)

    2008-06-15

    The German federal government provides a guide book ''Sustainable Buildings''[5]. The guide book contains principles for the design, construction and operation of buildings. Furthermore it provides procedures to assess economical and ecological but also sociocultural factors. The German Federal Ministry of Transport, Building and Urban Affairs is planning to enhance the guide book. This article discusses criteria for assessing the sociocultural factor ''thermal comfort''. The criteria gained from a review of literature and standards are examined for their suitability as assessment criteria in the guide book. They should be applicable for residential and office buildings as well as for new and existing buildings. For the different building types feasible methods are suggested. So far standards provide several approaches to assess thermal comfort. For some of these criteria there is no simple calculation method available. Several standards exist addressing the same criterion but using different methods. There is a need to harmonize the standards. Further research is required to provide assessment methods for important factors influencing occupant's satisfaction. (Abstract Copyright [2008], Wiley Periodicals, Inc.) [German] Die Bundesregierung hat den Leitfaden ''Nachhaltiges Bauen'' fuer Bundesbauten[5] herausgegeben. Der Leitfaden enthaelt Grundsaetze fuer das Planen, Bauen und Nutzen von Bundesliegenschaften. Der Leitfaden ermoeglicht eine Bewertung von oekonomischen und oekologischen, aber auch soziokulturellen Faktoren. Das Bundesministerium fuer Verkehr, Bau und Stadtentwicklung plant nun den Leitfaden fortzuschreiben. Mit vorliegender Publikation sollen Kriterien zur Bewertung des Raumklimas mit dem Schwerpunkt thermische Behaglichkeit der Nutzer aufgezeigt werden. Hierzu wird der bekannte Stand des Wissens (Literatur, Normen, Richtlinien) herangezogen und bezueglich der Eignung als Kriterium im

  19. Topic Teamwork: A Collaborative Integrative Model for Increasing Student-Centered Learning in Grades K-12.

    Science.gov (United States)

    Christie, Brett

    2000-01-01

    Describes the benefits of "topic teamwork," an interdisciplinary model designed to make integrative teaching a well-structured, cooperative effort involving all teachers and students. The article presents examples of and strategies for integrating physical education with other subject areas and for assessing topic teamwork, concluding that topic…

  20. Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy

    DEFF Research Database (Denmark)

    Salale, Nesrin; Treldal, Charlotte; Mogensen, Stine;

    2014-01-01

    Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE. Ninety-nine adult...... with a lidocaine spray proved to be a superior option as topical pharyngeal anesthetic before an UGE....

  1. Application of fisheries management techniques to assessing impacts: task I report. [Assessment of chemical, radiological, and thermal impacts of nuclear power plants on fish populations

    Energy Technology Data Exchange (ETDEWEB)

    McKenzie, D.H.; Baker, K.S.; Fickeisen, D.H.; Metzger, R.M.; Skalski, J.R.

    1979-03-01

    Task I efforts examined the available fisheries management techniques and assessed their potential application in a confirmatory monitoring program. The objective of such monitoring programs is to confirm that the prediction of an insignificant impact (usually made in the FES) was correct. Fisheries resource managers have developed several tools for assessing the fish population response to stress (exploitation) and they were thought potentially useful for detecting nuclear power plant impacts. Techniques in three categories were examined; catch removal, population dynamics, and nondestructive censuses, and the report contains their description, examples of application, advantages, and disadvantages. The techniques applied at nuclear power plant sites were examined in detail to provide information on implementation and variability of specific approaches. The most suitable techniques to incorporate into a monitoring program confirming no impact appear to be those based on Catch Per Unity Effort (CPUE) and hydroacoustic data. In some specific cases, age and growth studies and indirect census techniques may be beneficial. Recommendations for task II efforts to incorporate these techniques into monitoring program designs are presented. These include development of guidelines for; (1) designing and implementing a data collection program; (2) interpreting these data and assessing the occurrence of impact, and (3) establishment of the monitoring program's ability to detect changes in the affected populations.

  2. Thermal properties of nanofluids.

    Science.gov (United States)

    Philip, John; Shima, P D

    2012-11-15

    Colloidal suspensions of fine nanomaterials in the size range of 1-100 nm in carrier fluids are known as nanofluids. For the last one decade, nanofluids have been a topic of intense research due to their enhanced thermal properties and possible heat transfer applications. Miniaturization and increased operating speeds of gadgets warranted the need for new and innovative cooling concepts for better performance. The low thermal conductivity of conventional heat transfer fluid has been a serious impediment for improving the performance and compactness of engineering equipments. Initial studies on thermal conductivity of suspensions with micrometer-sized particles encountered problems of rapid settling of particles, clogging of flow channels and increased pressure drop in the fluid. These problems are resolved by using dispersions of fine nanometer-sized particles. Despite numerous experimental and theoretical studies, it is still unclear whether the thermal conductivity enhancement in nanofluids is anomalous or within the predictions of effective medium theory. Further, many reports on thermal conductivity of nanofluids are conflicting due to the complex issues associated with the surface chemistry of nanofluids. This review provides an overview of recent advances in the field of nanofluids, especially the important material properties that affect the thermal properties of nanofluids and novel approaches to achieve extremely high thermal conductivities. The background information is also provided for beginners to better understand the subject.

  3. Assessment of the effectiveness of silver-coated dressing, chlorhexidine acetate (0.5%), citric acid (3%), and silver sulfadiazine (1%) for topical antibacterial effects against the multi-drug resistant Pseudomonas aeruginosa infecting full-skin thickness burn wounds on rats.

    Science.gov (United States)

    Yabanoglu, Hakan; Basaran, Ozgur; Aydogan, Cem; Azap, Ozlem Kurt; Karakayali, Feza; Moray, Gokhan

    2013-01-01

    The aim of this study was to compare the effects of four different topical antimicrobial dressings on a multi-drug resistant Pseudomonas aeruginosa contaminated full-thickness burn wound rat model. A total of 40 adult male Wistar albino rats were used. The control group (group 1), silver sulfadiazine (1%) group 2, chlorhexidine acetate (0.5%) group 3, citric acid (3%) group 4, and silver-coated dressing group 5 were compared to assess the antibacterial effects of a daily application to a 30% full-skin thickness burn wound seeded 10 minutes earlier with 10(8) CFU (colony forming unit)/0.5 mL of a multi-drug resistant Pseudomonas aeruginosa strain. Five groups (1 control group and 4 treatment groups) were compared. The administration of third-degree burns to all rats was confirmed based on histopathologic data. The tissue cultures from groups 2 and 5 exhibited significant differences compared to those of the other 3 groups, whereas no significant differences were observed between groups 1, 3, and 4. The effectiveness of the treatments was as follows: 1% silver sulfadiazine > silver-coated dressing > 3% citric acid > 0.5% chlorhexidine acetate > control group. Our results supported the efficacy of topical therapy by silver sulfadiazine and silver-coated dressing on infections caused by multi-drug resistant Pseudomonas spp.

  4. Topical delivery of clobetasol propionate loaded microemulsion based gel for effective treatment of vitiligo--part II: rheological characterization and in vivo assessment through dermatopharmacokinetic and pilot clinical studies.

    Science.gov (United States)

    Patel, Hetal K; Barot, Bhavesh S; Parejiya, Punit B; Shelat, Pragna K; Shukla, Arunkumar

    2014-07-01

    Vitiligo is a non contagious acquired pigmentation disorder with limited treatment possibilities. Clobetasol propionate (CP) is the drug-of-choice for vitiligo which suppresses the immune system by reducing immunoglobulin action and causes the restoration of melanocytes leading to repigmentation of skin. However, despite being effective, its low and variable bioavailability prompt for development of novel carrier that could effectively target CP to site of action without producing undesirable side-effects. Low solubility of CP in subsequent poor in vivo bioavailability was overcome by formulating microemulsion based gel of CP (MBC) which would enhance the percutaneous transport of CP into and across the skin barrier. Comprehensive characterization of MBC was carried out for viscosity, gel strength and rheological behavior. In vitro studies revealed much higher drug release, skin penetration and enhanced skin accumulation as compared to control (Cream of CP). In vitro and in vivo occlusion studies demonstrated similar occlusiveness for MBC and control. MBC exhibited 3.16 times higher stratum corneum CP levels compared to control. Visualization of cutaneous uptake in vivo using laser scanning microscopy confirmed targeting of CP to epidermis and dermis. Dermatopharmacokinetic studies of MBC showed enhanced drug deposition of CP in skin layers. MBC was assessed for in vivo efficacy by single blind randomized pilot clinical study. The efficacy was assessed by vitiligo area scoring index (VASI) method. After completion of trial, repigmentation of vitiligo patches in patients were evaluated and scored. MBC was superior in terms of faster repigmentation and efficacy when compared with control (p valuevitiligo patients.

  5. Experimental assessment of thermal effects of high power density light stimulation for optogenetics control of deep brain structures (Conference Presentation)

    Science.gov (United States)

    Senova, Suhan; Scisniak, Ilona; Chiang, Chih Chieh; Doignon, Isabelle; Martin, Claire; Palfi, Stephane; Chaillet, Antoine; Pain, Frederic

    2016-03-01

    2D surface maps of light distribution and temperature increase were recorded in wild type anesthetized rats brains during 90s light stimulation at 478nm (blue) and 638nm (red) with continuous or pulsed optical stimulations with corresponding power ranging from 100 up to 1200 mW/mm² at the output of an optical fiber. Post mortem maps were recorded in the same animals to assess the cooling effect of blood flow. Post mortem histological analysis were carried out to assess whether high power light stimulations had phototoxic effects or could trigger non physiological functional activation. Temperature increase remains below physiological changes (0,5 -1°) for stimulations up to 400mW/mm² at 40Hz. . Histology did not show significant irreversible modifications or damage to the tissues. The spatial profile of light distribution and heat were correlated and demonstrate as expected a rapid attenuation with diatnce to the fiber.

  6. Solidification Features of Butadiene and Piperylene Copolymers and Assessment of Thermal-Oxidative Stability of Elastic Polyurethane on its Basis

    Directory of Open Access Journals (Sweden)

    Vasiliyp. Medvedev

    2017-02-01

    Full Text Available The research results given in this article are predetermined by the necessity of research intensification aimed at finding alternatives reactive oligomers for expanding the range of available compositions of such purpose. At the assessment of technics level in the area of binders for synthetic sports surfaces promising use of the above products as reactive oligomers and prepolymers for the realization of free-form molding surfaces was found.

  7. Assessment of Models of Galactic Thermal Dust Emission Using COBE/FIRAS and COBE/DIRBE Observations

    Science.gov (United States)

    Odegard, N.; Kogut, A.; Chuss, D. T.; Miller, N. J.

    2016-09-01

    Accurate modeling of the spectrum of thermal dust emission at millimeter wavelengths is important for improving the accuracy of foreground subtraction for cosmic microwave background (CMB) measurements, for improving the accuracy with which the contributions of different foreground emission components can be determined, and for improving our understanding of dust composition and dust physics. We fit four models of dust emission to high Galactic latitude COBE/FIRAS and COBE/DIRBE observations from 3 mm to 100 μm and compare the quality of the fits. We consider the two-level systems (TLS) model because it provides a physically motivated explanation for the observed long wavelength flattening of the dust spectrum and the anti-correlation between emissivity index and dust temperature. We consider the model of Finkbeiner et al. because it has been widely used for CMB studies, and the generalized version of this model that was recently applied to Planck data by Meisner and Finkbeiner. For comparison we have also fit a phenomenological model consisting of the sum of two graybody components. We find that the two-graybody model gives the best fit and the FDS model gives a significantly poorer fit than the other models. The Meisner and Finkbeiner model and the TLS model remain viable for use in Galactic foreground subtraction, but the FIRAS data do not have a sufficient signal-to-noise ratio to provide a strong test of the predicted spectrum at millimeter wavelengths.

  8. Monte Carlo assessment of soil moisture effect on high-energy thermal neutron capture gamma-ray by 14N.

    Science.gov (United States)

    Pazirandeh, Ali; Azizi, Maryam; Farhad Masoudi, S

    2006-01-01

    Among many conventional techniques, nuclear techniques have shown to be faster, more reliable, and more effective in detecting explosives. In the present work, neutrons from a 5 Ci Am-Be neutron source being in water tank are captured by elements of soil and landmine (TNT), namely (14)N, H, C, and O. The prompt capture gamma-ray spectrum taken by a NaI (Tl) scintillation detector indicates the characteristic photo peaks of the elements in soil and landmine. In the high-energy region of the gamma-ray spectrum, besides 10.829 MeV of (15)N, single escape (SE) and double escape (DE) peaks are unmistakable photo peaks, which make the detection of concealed explosive possible. The soil has the property of moderating neutrons as well as diffusing the thermal neutron flux. Among many elements in soil, silicon is more abundant and (29)Si emits 10.607 MeV prompt capture gamma-ray, which makes 10.829 MeV detection difficult. The Monte Carlo simulation was used to adjust source-target-detector distances and soil moisture content to yield the best result. Therefore, we applied MCNP4C for configuration very close to reality of a hidden landmine in soil.

  9. Assessment of morphine-induced hyperalgesia and analgesic tolerance in mice using thermal and mechanical nociceptive modalities.

    Science.gov (United States)

    Elhabazi, Khadija; Ayachi, Safia; Ilien, Brigitte; Simonin, Frédéric

    2014-07-29

    Opioid-induced hyperalgesia and tolerance severely impact the clinical efficacy of opiates as pain relievers in animals and humans. The molecular mechanisms underlying both phenomena are not well understood and their elucidation should benefit from the study of animal models and from the design of appropriate experimental protocols. We describe here a methodological approach for inducing, recording and quantifying morphine-induced hyperalgesia as well as for evidencing analgesic tolerance, using the tail-immersion and tail pressure tests in wild-type mice. As shown in the video, the protocol is divided into five sequential steps. Handling and habituation phases allow a safe determination of the basal nociceptive response of the animals. Chronic morphine administration induces significant hyperalgesia as shown by an increase in both thermal and mechanical sensitivity, whereas the comparison of analgesia time-courses after acute or repeated morphine treatment clearly indicates the development of tolerance manifested by a decline in analgesic response amplitude. This protocol may be similarly adapted to genetically modified mice in order to evaluate the role of individual genes in the modulation of nociception and morphine analgesia. It also provides a model system to investigate the effectiveness of potential therapeutic agents to improve opiate analgesic efficacy.

  10. Assessment of heavy metals exposure, noise and thermal safety in the ambiance of a vacuum metallurgy separation system for recycling heavy metals from crushed e-wastes.

    Science.gov (United States)

    Zhan, Lu; Xu, Zhenming

    2014-12-01

    Vacuum metallurgy separation (VMS) is a technically feasible method to recover Pb, Cd and other heavy metals from crushed e-wastes. To further determine the environmental impacts and safety of this method, heavy metals exposure, noise and thermal safety in the ambiance of a vacuum metallurgy separation system are evaluated in this article. The mass concentrations of total suspended particulate (TSP) and PM10 are 0.1503 and 0.0973 mg m(-3) near the facilities. The concentrations of Pb, Cd and Sn in TSP samples are 0.0104, 0.1283 and 0.0961 μg m(-3), respectively. Health risk assessments show that the hazard index of Pb is 3.25 × 10(-1) and that of Cd is 1.09 × 10(-1). Carcinogenic risk of Cd through inhalation is 1.08 × 10(-5). The values of the hazard index and risk indicate that Pb and Cd will not cause non-cancerous effects or carcinogenic risk on workers. The noise sources are mainly the mechanical vacuum pump and the water cooling pump. Both of them have the noise levels below 80 dB (A). The thermal safety assessment shows that the temperatures of the vacuum metallurgy separation system surface are all below 303 K after adopting the circulated water cooling and heat insulation measures. This study provides the environmental information of the vacuum metallurgy separation system, which is of assistance to promote the industrialisation of vacuum metallurgy separation for recovering heavy metals from e-wastes.

  11. Nuffield Advanced Chemistry Courses Topic 10

    Science.gov (United States)

    Education in Science, 1975

    1975-01-01

    Presents an alternative series of investigations replacing the propanone-trichloromethane system (Topic 10) in the Nuffield A-Level course. A trichloromethane-ethyl ethanoate (acetate) system presented in four experiments give good results and removed the dangers arising from the other system. Topic 10 need not be re-written, just the replacement…

  12. Topic Maps Based Project Knowledge Management

    Institute of Scientific and Technical Information of China (English)

    Wu Xiaofan; Zhou Liang; Zhang Lei; Li Lingzhi; Ding Qiulin

    2006-01-01

    Based on topic maps, a preprocessing scheme using similarity comparision is presented and applied in knowledge management.Topic and occurrence-oriented merging algorithm is also introduced to implement knowledge integration for the sub-system. An Omnigator-supported example from an aeroaustic institute is utilised to validate the preprocessing method and the result indicates it can speed up the research schedule.

  13. Severe photosensitivity reaction induced by topical diclofenac

    OpenAIRE

    Akat, Pramod B.

    2013-01-01

    Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications.

  14. Fostering Topic Knowledge: Essential for Academic Writing

    Science.gov (United States)

    Proske, Antje; Kapp, Felix

    2013-01-01

    Several researchers emphasize the role of the writer's topic knowledge for writing. In academic writing topic knowledge is often constructed by studying source texts. One possibility to support that essential phase of the writing process is to provide interactive learning questions which facilitate the construction of an adequate situation…

  15. Prioritizing dermatoses: rationally selecting guideline topics

    NARCIS (Netherlands)

    Borgonjen, R.J.; Everdingen, J.J. van; Kerkhof, P.C.M. van de; Spuls, P.I.

    2015-01-01

    BACKGROUND: Clinical practice guideline (CPG) development starts with selecting appropriate topics, as resources to develop a guideline are limited. However, a standardized method for topic selection is commonly missing and the way different criteria are used to prioritize is not clear. OBJECTIVES:

  16. Severe photosensitivity reaction induced by topical diclofenac

    Directory of Open Access Journals (Sweden)

    Pramod B Akat

    2013-01-01

    Full Text Available Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications.

  17. Corneal staining after treatment with topical tetracycline

    NARCIS (Netherlands)

    R. Lapid-Gortzak; C.P. Nieuwendaal; A.R. Slomovic; L. Spanjaard

    2006-01-01

    Purpose: The purpose of this paper is to report a case of corneal staining after treatment with topical tetracycline. Methods: A patient with crystalline keratopathy caused by Streptococcus viridans after corneal transplantation was treated topically with tetracycline eye drops, based on results of

  18. Psoriasis: improving adherence to topical therapy.

    NARCIS (Netherlands)

    Feldman, S.R.; Horn, E.J.; Balkrishnan, R.; Basra, M.K.; Finlay, A.Y.; McCoy, D.; Menter, A.; Kerkhof, P.C.M. van de

    2008-01-01

    Topical therapy has an important role in psoriasis treatment. It is efficacious and has a favorable safety profile as demonstrated in clinical trials. However, poor treatment outcomes from topical therapy regimens likely result from poor adherence and ineffective use of the medication. The Internati

  19. Aerodynamics of wind turbines emerging topics

    CERN Document Server

    Amano, R S

    2014-01-01

    Focusing on Aerodynamics of Wind Turbines with topics ranging from Fundamental to Application of horizontal axis wind turbines, this book presents advanced topics including: Basic Theory for Wind turbine Blade Aerodynamics, Computational Methods, and Special Structural Reinforcement Technique for Wind Turbine Blades.

  20. Histiocytosis X: treatment with topical nitrogen mustard.

    Science.gov (United States)

    Berman, B; Chang, D L; Shupack, J L

    1980-07-01

    The case histories of two elderly patients with cutaneous histiocytosis X treated topically with nitrogen mustard are presented. The cutaneous lesions cleared within 2 to 3 weeks, and remission was maintained with daily topical administration of nitrogen mustard. The clinical impression of improvement was substantiated by light and electron microscopic studies prior to and after therapy.

  1. Generating focused topic-specific sentiment lexicons

    NARCIS (Netherlands)

    Jijkoun, V.; de Rijke, M.; Weerkamp, W.

    2010-01-01

    We present a method for automatically generating focused and accurate topic-specific subjectivity lexicons from a general purpose polarity lexicon that allow users to pin-point subjective on-topic information in a set of relevant documents. We motivate the need for such lexicons in the field of medi

  2. Correlated Topic Model for Web Services Ranking

    Directory of Open Access Journals (Sweden)

    Mustapha AZNAG

    2013-07-01

    Full Text Available With the increasing number of published Web services providing similar functionalities, it’s very tedious for a service consumer to make decision to select the appropriate one according to her/his needs. In this paper, we explore several probabilistic topic models: Probabilistic Latent Semantic Analysis (PLSA, Latent Dirichlet Allocation (LDA and Correlated Topic Model (CTM to extract latent factors from web service descriptions. In our approach, topic models are used as efficient dimension reduction techniques, which are able to capture semantic relationships between word-topic and topic-service interpreted in terms of probability distributions. To address the limitation of keywords-based queries, we represent web service description as a vector space and we introduce a new approach for discovering and ranking web services using latent factors. In our experiment, we evaluated our Service Discovery and Ranking approach by calculating the precision (P@n and normalized discounted cumulative gain (NDCGn.

  3. Topical antioxidants in radiodermatitis: a clinical review.

    Science.gov (United States)

    Kodiyan, Joyson; Amber, Kyle T

    2015-09-01

    Radiation-induced skin toxicity is the most prevalent side effect of radiation therapy. Not only does it have a significant effect on patients' quality of life, but it also results in poor follow-up and early termination of radiotherapy treatment. Several skin care practices and topical applications have been studied in the field of radiodermatitis, including skin washing, topical steroids, and mechanical skin barriers. Aside from these methods, many patients turn to complementary and alternative medicine for the prevention and treatment of radiodermatitis. Many of these alternative therapies are topically applied antioxidants. While the rationale behind the use of antioxidants in treating radiodermatitis is strong, clinical studies have been far less consistent. Even in large scale randomised controlled trials, findings have been limited by the inconsistent use of topical vehicles and placebos. In this article, the authors review the role of topical antioxidants to better help the practitioner navigate through different available skin directed antioxidants.

  4. Zr–Cu thin film metallic glasses: An assessment of the thermal stability and phases’ transformation mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Apreutesei, M. [MATEIS Laboratory-INSA de Lyon, Bât. B. Pascal, 7 Avenue Jean Capelle, 69621 Villeurbanne Cedex (France); Steyer, P., E-mail: philippe.steyer@insa-lyon.fr [MATEIS Laboratory-INSA de Lyon, Bât. B. Pascal, 7 Avenue Jean Capelle, 69621 Villeurbanne Cedex (France); Billard, A. [LERMPS-UTBM, Site de Montbéliard, 90010 Belfort Cédex (France); Joly-Pottuz, L.; Esnouf, C. [MATEIS Laboratory-INSA de Lyon, Bât. B. Pascal, 7 Avenue Jean Capelle, 69621 Villeurbanne Cedex (France)

    2015-01-15

    Highlights: • Binary Zr–Cu TFMGs with high glass-forming ability were fabricated. • Crystallization kinetics of Zr–Cu glassy films was studied. • Crystallization is governed by multi-stage step diffusion-controlled growth. • Films exhibit smooth and dense surface morphology and vein-like features. - Abstract: The PVD co-sputtering technology is an efficient way to deposit Zr–Cu thin film metallic glass in a wide composition range. The structural stability and crystallization behavior of metallic glass films are investigated by in situ X-ray diffraction (XRD) via heating up to 873 K. The glassy films within the 33.3–89.1 at.% Cu range maintained their amorphous structure at temperatures higher than 550 K. Within this chemical composition range, films exhibit a smooth and dense surface morphology with 100 nm-sized grains and vein-like features. Glassy films revealed a high thermal stability as reflected by differential scanning calorimetry experiments and in situ high temperature XRD analysis. It was found that the structure evolved with the temperature and copper contents from a highly textured {1 1 1} crystallized fcc-Zr to intermetallic CuZr{sub 2}, Cu{sub 10}Zr{sub 7}, Cu{sub 51}Zr{sub 14} phases to finally {1 1 1} crystallized fcc-Cu. Mechanisms involved in the structural changes of the glassy films together with the multi-stage crystallization process are discussed in the light of the copper contents.

  5. Recycled-PET fibre based panels for building thermal insulation: environmental impact and improvement potential assessment for a greener production.

    Science.gov (United States)

    Ingrao, Carlo; Lo Giudice, Agata; Tricase, Caterina; Rana, Roberto; Mbohwa, Charles; Siracusa, Valentina

    2014-09-15

    A screening of Life Cycle Assessment for the evaluation of the damage arising from the production of 1 kg of recycled Polyethylene Terephthalate (RPET) fibre-based panel for building heat insulation was carried out according to the ISO 14040:2006 and 14044:2006. All data used were collected on site based on observations during site visits, review of documents and interviews with technical personnel and management. These data were processed by using SimaPro 7.3.3, accessing the Ecoinvent v.2.2 database and using the Impact 2002+ method. The study showed damage to be equal to 0.000299 points mostly due to the: 1) PET thermo-bonding fibre supply from China by means of a freight-equipped intercontinental aircraft; 2) production of bottle-grade granulate PET; 3) medium voltage electricity consumption during the manufacturing of RPET fibre panel. It was also highlighted that there were environmental benefits due to recycling through mainly avoiding significant emissions and reduced resource consumption. An improvement assessment was carried out to find solutions aimed at reducing the damage coming from the most impacting phases. Furthermore, the environmental impacts due to the production of the analysed RPET fibre-based panel were compared to other materials with the same insulating function, such as polystyrene foam, rock wool and cork slab. Finally, the environmental benefits of the recycling of PET bottles for flake production were highlighted compared to other treatment scenarios such as landfill and municipal incineration.

  6. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  7. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  8. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  9. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  10. Chronic Heat Stress and Cognitive Development: An Example of Thermal Conditions Influencing Human Development

    Science.gov (United States)

    Riniolo, Todd C.; Schmidt, Louis A.

    2006-01-01

    Although thermal conditions influence the development of living organisms in a wide variety of ways, this topic has been recently ignored in humans. This paper reintroduces thermal conditions as a topic of importance for developmentalists by presenting an example of how thermal conditions are hypothesized to influence a particular developmental…

  11. Development and assessment of Multi-dimensional flow models in the thermal-hydraulic system analysis code MARS

    Energy Technology Data Exchange (ETDEWEB)

    Chung, B. D.; Bae, S. W.; Jeong, J. J.; Lee, S. M

    2005-04-15

    A new multi-dimensional component has been developed to allow for more flexible 3D capabilities in the system code, MARS. This component can be applied in the Cartesian and cylindrical coordinates. For the development of this model, the 3D convection and diffusion terms are implemented in the momentum and energy equation. And a simple Prandtl's mixing length model is applied for the turbulent viscosity. The developed multi-dimensional component was assessed against five conceptual problems with analytic solution. And some SETs are calculated and compared with experimental data. With this newly developed multi-dimensional flow module, the MARS code can realistic calculate the flow fields in pools such as those occurring in the core, steam generators and IRWST.

  12. Literature survey results: Topical report

    Energy Technology Data Exchange (ETDEWEB)

    Willson, W.G.; Ness, R.O.; Hendrikson, J.G.; Entzminger, J.A.; Jha, M.; Sinor, J.E.

    1988-01-01

    This report reviews mild gasification processes with respect to processing conditions and configurations. Special emphasis was placed on processes which could be commercialized within five years. Detailed market information was provided by J.E. Sinor concerning markets and economic considerations of the various processing steps. Processing areas studied include coal cleaning; mild gasification; and upgrading of the char, condensables, and hydrocarbon gases. Pros and cons in the different processing areas as well as ''gaps'' in pertinent data were identified and integrated into a detailed process development program. The report begins with a summary of the market assessment and an evaluation of the co-product. The impacts of feed materials and operating parameters--including coal rank, heating rate, pressure, agglomeration, temperature, and feed gas composition--on the co- products and processes were evaluated through a literature survey. Recommendations were made as to the preferred product specifications and operating parameters for a commercial plant. A literature review of mild gasification processes was conducted and evaluated with regard to product specification and operating parameters. Two candidate processes were chosen and discussed in detail with respect to scale-up feasibility. Recommendations were then made to process development needs to further consideration of the two processes. 129 refs., 33 figs., 16 tabs.

  13. Gellan gum fluid gels for topical administration of diclofenac.

    Science.gov (United States)

    Mahdi, Mohammed H; Conway, Barbara R; Mills, Thomas; Smith, Alan M

    2016-12-30

    Diclofenac topical formulations are often preferred for drug administration to patients who experience serious GIT problems. Absorption of the drug through the skin, however, can be challenging due to the natural protective feature of the stratum corneum (SC). In this article, fluid gels prepared from gellan gum were explored as a topical drug delivery vehicle. Rheological analysis of the formulations showed that it was possible to produce a topical gel with a viscosity and the mechanical strength similar to that of the commercially available Voltaren(®) gel using 1% w/w of a 50:50 low acyl/high acyl (LA/HA) gellan blend. Soft-tribology was used to assess the lubrication properties of gellan fluid gels. The lubrication of the gellan gum fluid gel formulations at high rubbing speeds was similar to the lubrication of the Voltaren(®) gel. The use of gellan gum dramatically increased skin permeation of diclofenac when compared with the commercially available formulation and could be controlled by changing the gellan gum concentration and/or sodium ion concentration in the formulation. This study highlights the potential use of fluid gels that can be easily tuned to have physical properties suitable for topical formulations with the added advantage of increasing drug permeation.

  14. Successful topical dissolution of cholesterol gallbladder stones using ethyl propionate.

    Science.gov (United States)

    Hofmann, A F; Amelsberg, A; Esch, O; Schteingart, C D; Lyche, K; Jinich, H; Vansonnenberg, E; D'Agostino, H B

    1997-06-01

    Topical dissolution of cholesterol gallbladder stones using methyl tert-butyl ether (MTBE) is useful in symptomatic patients judged too ill for surgery. Previous studies showed that ethyl propionate (EP), a C5 ester, dissolves cholesterol gallstones rapidly in vitro, but differs from MTBE in being eliminated so rapidly by the liver that blood levels remain undetectable. Our aim was to test EP as a topical dissolution agent for cholesterol gallbladder stones. Five high-risk patients underwent topical dissolution of gallbladder stones by EP. In three patients, the solvent was instilled via a cholecystostomy tube placed previously to treat acute cholecystitis; in two patients, a percutaneous transhepatic catheter was placed in the gallbladder electively. Gallstone dissolution was assessed by chromatography, by gravimetry, and by catheter cholecystography. Total dissolution of gallstones was obtained in four patients after 6-10 hr of lavage; in the fifth patient, partial gallstone dissolution facilitated basketing of the stones. In two patients, cholesterol dissolution was measured and averaged 30 mg/min. Side effects were limited to one episode of transient hypotension and pain at the infusion site; no patient developed somnolence or nausea. Gallstone elimination was associated with relief of symptoms. EP is an acceptable alternative to MTBE for topical dissolution of cholesterol gallbladder stones in high-risk patients. The lower volatility and rapid hepatic extraction of EP suggest that it may be preferable to MTBE in this investigational procedure.

  15. Digital Social Network Mining for Topic Discovery

    Science.gov (United States)

    Moradianzadeh, Pooya; Mohi, Maryam; Sadighi Moshkenani, Mohsen

    Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

  16. Control of pain with topical plant medicines

    Institute of Scientific and Technical Information of China (English)

    James; David; Adams; Jr.; Xiaogang; Wang

    2015-01-01

    Pain is normally treated with oral nonsteroidal anti-inflammatory agents and opioids. These drugs are dangerous and are responsible for many hospitalizations and deaths. It is much safer to use topical preparations made from plants to treat pain, even severe pain. Topical preparations must contain compounds that penetrate the skin, inhibit pain receptors such as transient receptor potential cation channels and cyclooxygenase-2, to relieve pain. Inhibition of pain in the skin disrupts the pain cycle and avoids exposure of internal organs to large amounts of toxic compounds. Use of topical pain relievers has the potential to save many lives, decrease medical costs and improve therapy.

  17. Large scale topic modeling made practical

    DEFF Research Database (Denmark)

    Wahlgreen, Bjarne Ørum; Hansen, Lars Kai

    2011-01-01

    Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number of docume......Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number...... topics at par with a much larger case specific vocabulary....

  18. An assessment of wind tunnel test data on flexible thermal protection materials and results of new fatigue tests of threads

    Science.gov (United States)

    Coe, Charles F.

    1985-01-01

    Advanced Flexible Reusable Surface Insulation (AFRSI) was developed as a replacement for the low-temperature (white) tiles on the Space Shuttle. The first use of the AFRSI for an Orbiter flight was on the OMS POD of Orbiter (OV-099) for STS-6. Post flight examination after STS-6 showed that damage had occurred to the AFRSI during flight. The failure anomaly between previous wind-tunnel tests and STS-6 prompted a series of additional wind tunnel tests to gain an insight as to the cause of the failure. An assessment of all the past STS-6 wind tunnel tests pointed out the sensitivity of the test results to scaling of dynamic loads due to the difference of boundary layer thickness, and the material properties as a result of exposure to heating. The thread component of the AFRSI was exposed to fatigue testing using an apparatus that applied pulsating aerodynamic loads on the threads similar to the loads caused by an oscillating shock. Comparison of the mean values of the number-of-cycles to failure showed that the history of the thread was the major factor in its performance. The thread and the wind tunnel data suggests a mechanism of failure for the AFRSI.

  19. Assessment

    Institute of Scientific and Technical Information of China (English)

    Geoff Brindley

    2005-01-01

    @@ Introduction TERMINOLOGY AND KEY CONCEPTS The term assessment refers to a variety of ways of collecting information on a learner's language ability or achievement. Although testing and assessment are often used interchangeably, the latter is an umbrella term encompassing measurement instruments administered on a ‘one-off’ basis such as tests, as well as qualitative methods of monitoring and recording student learning such as observation, simulations of project work. Assessment is also distinguished from evaluation which is concerned with the overall language programme and not just with what individual students have learnt. Proficiency assessment refers to the assessment of general language abilities acquired by the learner independent of a course of study.This kind of assessment is often done through the administration of standardised commercial language-proficency tests. On the other hand, assessment of achievement aims to establish what a student had learned in relation to a particular course or curriculum (thus frequently carried out by the teacher) .Achievement assesssment may be based either on the specific content of the course or on the course objectives (Hughes 1989).

  20. Risk assessment of an old landfill regarding the potential of gaseous emissions--a case study based on bioindication, FT-IR spectroscopy and thermal analysis.

    Science.gov (United States)

    Tintner, Johannes; Smidt, Ena; Böhm, Katharina; Matiasch, Lydia

    2012-12-01

    Risk assessment of two sections (I and II) of an old landfill (ALH) in Styria (Austria) in terms of reactivity of waste organic matter and the related potential of gaseous emissions was performed using conventional parameters and innovative tools to verify their effectiveness in practice. The ecological survey of the established vegetation at the landfill surface (plant sociological relevés) indicated no relevant emissions over a longer period of time. Statistical evaluation of conventional parameters reveals that dissolved organic carbon (DOC), respiration activity (RA(4)), loss of ignition (LOI) and total inorganic carbon (TIC) mostly influence the variability of the gas generation sum (GS(21)). According to Fourier Transform Infrared (FT-IR) spectral data and the results of the classification model the reactivity potential of the investigated sections is very low which is in accordance with the results of plant sociological relevés and biological tests. The interpretation of specific regions in the FT-IR spectra was changed and adapted to material characteristics. Contrary to mechanically-biologically treated (MBT) materials, where strong aliphatic methylene bands indicate reactivity, they are rather assigned to the C-H vibrations of plastics in old landfill materials. This assumption was confirmed by thermal analysis and the characteristic heat flow profile of plastics containing landfill samples. Therefore organic carbon contents are relatively high compared to other stable landfills as shown by a prediction model for TOC contents based on heat flow profiles and partial least squares regression (PLS-R). The stability of the landfill samples, expressed by the relation of CO(2) release and enthalpies, was compared to unreactive landfills, archeological samples, earthlike materials and hardly degradable organic matter. Due to the material composition and the aging process the landfill samples are located between hardly degradable, but easily combustible

  1. Assessment of temperature peaks reached during a wildfire. An approach using X-ray diffraction and differential thermal analysis

    Science.gov (United States)

    Jiménez-González, Marco A.; Jordán, Antonio; Zavala, Lorena M.; Mataix-Solera, Jorge; Bárcenas-Moreno, Gema; Jiménez-Morillo, Nicasio T.; Bellinfante, Nicolás

    2014-05-01

    1. INTRODUCTION Wildfires may induce important chemical and physical changes in soils, including changes in the soil composition, mineralogical changes, soil water repellency, aggregate stability or textural changes (Bodí et al., 2013; Granged et al., 2011a, 2011b, 2011c; Jordán et al., 2011, 2013; Mataix-Solera et al., 2011). As these changes usually occur after threshold temperature peaks, the assessment of these helps to explain many of the processes occurring during burning and in the postfire (Pereira et al., 2012, 2013; Shakesby, 2011). In July 2011, a wildfire burnt a pine forested area (50 ha) in Gorga (Alicante, SW Spain), approximately at 38° 44.3' N and 0° 20.7' W. Main soil type is Lithic Xerorthent developed from limestone. The study of mineralogical changes in soil after a wildfire should help to assess fire temperature peaks reached during burning. In order to study the impact of fire temperature on mineralogical changes and determine temperature peaks during burning, burnt soil plots under shrubland were randomly collected (0-5 cm deep). Control samples from adjacent unburnt areas were also collected for control. 2. METHODS Soil samples were ground using an agate mortar and then sieved (420 °C). In samples heated at 500 and 700 °C, these changes are not appreciated as they occurred during calcination. In the 300 °C heated sample, some of these changes partially occurred. Peaks observed approximately at 100 °C correspond to release of absorbed water. Peaks at 900 °C are a consequence of destruction of calcite. Finally a peak was observed at 680 °C in the control sample may be explained as a consequence of the destruction of blixite (Pb8(OH)2Cl4), which was present in control samples (1.1%) but not in burnt samples. This peak is probably masked in heated samples. REFERENCES Bodí, M.B., Muñoz-Santa, I., Armero, C., Doerr, S.H., Mataix-Solera, J., Cerdà, A. 2013. Spatial and temporal variations of water repellency and probability of its

  2. Pulmonary Rehabilitation: MedlinePlus Health Topic

    Science.gov (United States)

    ... Related Issues Breathing and Relaxation (National Jewish Health) DANCE Your Way to Healthier Lungs (American Association for Respiratory Care) Exercises (National Jewish Health) Oxygen Therapy: MedlinePlus Health Topic (National Library of Medicine) Also ...

  3. Corneal Neurotoxicity Due to Topical Benzalkonium Chloride

    OpenAIRE

    Sarkar, Joy; Chaudhary, Shweta; Namavari, Abed; Ozturk, Okan; Chang, Jin-Hong; Yco, Lisette; Sonawane, Snehal; Khanolkar, Vishakha; Hallak, Joelle; Jain, Sandeep

    2012-01-01

    Topical application of benzalkonium chloride (BAK) to the eye causes dose-related corneal neurotoxicity. Corneal inflammation and reduction in aqueous tear production accompany neurotoxicity. Cessation of BAK treatment leads to recovery of corneal nerve density.

  4. Topical cidofovir for refractory verrucae in children.

    Science.gov (United States)

    Gupta, Monique; Bayliss, Susan J; Berk, David R

    2013-01-01

    Warts are common and are a challenge to treat in some children, especially immunocompromised children and those who fail or cannot tolerate salicylic acid preparations and cryotherapy. Cidofovir, a nucleotide analogue with antiviral activity, has demonstrated promising results when compounded into a topical form to treat refractory warts. We present a retrospective institutional review of 12 children with refractory verrucae treated with 1% to 3% topical cidofovir compounded in an unscented moisturizing cream, applied every other day to daily. In our institutional series, only three patients (25%) demonstrated complete clearance of their verrucae. An additional four patients (33%) demonstrated partial clearance. Our experience using topical cidofovir has been less successful than previous institutional reviews, possibly because we used a lower concentration and less-frequent dosing. More studies are needed to better characterize the efficacy, safety, and dosing of topical cidofovir for the treatment of refractory warts.

  5. Diabetes: MedlinePlus Health Topic

    Science.gov (United States)

    ... Foundation for Medical Education and Research) Prevention and Risk Factors Choose More than 50 Ways to Prevent Type ... Resources for Living Well (National Diabetes Education Program) Diabetic Diet: MedlinePlus Health Topic (National Library of Medicine) ...

  6. Teenage Pregnancy: MedlinePlus Health Topic

    Science.gov (United States)

    ... Tips for Parents to Help Their Children Avoid Teen Pregnancy (National Campaign to Prevent Teen and Unplanned Pregnancy) - PDF Living With Pregnancy and Nutrition: MedlinePlus Health Topic (National Library of Medicine) Also ...

  7. Mining Concurrent Topical Activity in Microblog Streams

    CERN Document Server

    Panisson, A; Quaggiotto, M; Cattuto, C

    2014-01-01

    Streams of user-generated content in social media exhibit patterns of collective attention across diverse topics, with temporal structures determined both by exogenous factors and endogenous factors. Teasing apart different topics and resolving their individual, concurrent, activity timelines is a key challenge in extracting knowledge from microblog streams. Facing this challenge requires the use of methods that expose latent signals by using term correlations across posts and over time. Here we focus on content posted to Twitter during the London 2012 Olympics, for which a detailed schedule of events is independently available and can be used for reference. We mine the temporal structure of topical activity by using two methods based on non-negative matrix factorization. We show that for events in the Olympics schedule that can be semantically matched to Twitter topics, the extracted Twitter activity timeline closely matches the known timeline from the schedule. Our results show that, given appropriate techn...

  8. Pain Relievers: MedlinePlus Health Topic

    Science.gov (United States)

    ... Physicians) Also in Spanish Medicines for Pain: From Osteoarthritis to Muscle Pain (National Center for Farmworker Health, ... Institutes of Health Page last updated on 16 March 2017 Topic last reviewed: 29 December 2016

  9. Hip Replacement: MedlinePlus Health Topic

    Science.gov (United States)

    ... damage. The most common cause of damage is osteoarthritis . Osteoarthritis causes pain, swelling, and reduced motion in your ... Institutes of Health Page last updated on 17 March 2017 Topic last reviewed: 31 August 2016

  10. MedlinePlus Health Topic Web Service

    Data.gov (United States)

    U.S. Department of Health & Human Services — A search-based Web service that provides access to disease, condition and wellness information via MedlinePlus health topic data in XML format. The service accepts...

  11. Sports Safety: MedlinePlus Health Topic

    Science.gov (United States)

    ... exercise injuries Returning to sports after a back injury Sports physical Related Health Topics Sports Fitness Sports Injuries Water Safety (Recreational) Languages Hmong (Hmoob) Russian (Русский) ...

  12. Helpful Contacts - Agency List By Topic

    Data.gov (United States)

    U.S. Department of Health & Human Services — A database of agencies listed by state and topic to provide you with contact information for specific organizations or help you get answers to your Medicare related...

  13. Regulatory cross-cutting topics for fuel cycle facilities.

    Energy Technology Data Exchange (ETDEWEB)

    Denman, Matthew R.; Brown, Jason; Goldmann, Andrew Scott; Louie, David

    2013-10-01

    This report overviews crosscutting regulatory topics for nuclear fuel cycle facilities for use in the Fuel Cycle Research & Development Nuclear Fuel Cycle Evaluation and Screening study. In particular, the regulatory infrastructure and analysis capability is assessed for the following topical areas: Fire Regulations (i.e., how applicable are current Nuclear Regulatory Commission (NRC) and/or International Atomic Energy Agency (IAEA) fire regulations to advance fuel cycle facilities) Consequence Assessment (i.e., how applicable are current radionuclide transportation tools to support risk-informed regulations and Level 2 and/or 3 PRA) While not addressed in detail, the following regulatory topic is also discussed: Integrated Security, Safeguard and Safety Requirement (i.e., how applicable are current Nuclear Regulatory Commission (NRC) regulations to future fuel cycle facilities which will likely be required to balance the sometimes conflicting Material Accountability, Security, and Safety requirements.)

  14. Pharmacogenetics of ophthalmic topical β-blockers

    OpenAIRE

    Sidjanin, Duska J.; McCarty, Catherine A.; Patchett, Richard; Smith, Edward; Wilke, Russell A.

    2008-01-01

    Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure. Genetic variability has been postulated to contribute to interpersonal differences in efficacy and safety of topical β-blockers. This review summarizes clinically significant polymorphisms that have been identified in the β-adrenergic receptors (ADRB1, ADRB2 and ADRB3). The implications ...

  15. Topical steroid addiction in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Fukaya M

    2014-10-01

    Full Text Available Mototsugu Fukaya,1 Kenji Sato,2 Mitsuko Sato,3 Hajime Kimata,4 Shigeki Fujisawa,5 Haruhiko Dozono,6 Jun Yoshizawa,7 Satoko Minaguchi8 1Tsurumai Kouen Clinic, Nagoya, 2Department of Dermatology, Hannan Chuo Hospital, Osaka, 3Sato Pediatric Clinic, Osaka, 4Kimata Hajime Clinic, Osaka, 5Fujisawa Dermatology Clinic, Tokyo, 6Dozono Medical House, Kagoshima, 7Yoshizawa Dermatology Clinic, Yokohama, 8Department of Dermatology, Kounosu Kyousei Hospital, Saitama, Japan Abstract: The American Academy of Dermatology published a new guideline regarding topical therapy in atopic dermatitis in May 2014. Although topical steroid addiction or red burning skin syndrome had been mentioned as possible side effects of topical steroids in a 2006 review article in the Journal of the American Academy of Dermatology, no statement was made regarding this illness in the new guidelines. This suggests that there are still controversies regarding this illness. Here, we describe the clinical features of topical steroid addiction or red burning skin syndrome, based on the treatment of many cases of the illness. Because there have been few articles in the medical literature regarding this illness, the description in this article will be of some benefit to better understand the illness and to spur discussion regarding topical steroid addiction or red burning skin syndrome. Keywords: topical steroid addiction, atopic dermatitis, red burning skin syndrome, rebound, corticosteroid, eczema

  16. Characterizing interdisciplinarity of researchers and research topics using web search engines.

    Science.gov (United States)

    Sayama, Hiroki; Akaishi, Jin

    2012-01-01

    Researchers' networks have been subject to active modeling and analysis. Earlier literature mostly focused on citation or co-authorship networks reconstructed from annotated scientific publication databases, which have several limitations. Recently, general-purpose web search engines have also been utilized to collect information about social networks. Here we reconstructed, using web search engines, a network representing the relatedness of researchers to their peers as well as to various research topics. Relatedness between researchers and research topics was characterized by visibility boost-increase of a researcher's visibility by focusing on a particular topic. It was observed that researchers who had high visibility boosts by the same research topic tended to be close to each other in their network. We calculated correlations between visibility boosts by research topics and researchers' interdisciplinarity at the individual level (diversity of topics related to the researcher) and at the social level (his/her centrality in the researchers' network). We found that visibility boosts by certain research topics were positively correlated with researchers' individual-level interdisciplinarity despite their negative correlations with the general popularity of researchers. It was also found that visibility boosts by network-related topics had positive correlations with researchers' social-level interdisciplinarity. Research topics' correlations with researchers' individual- and social-level interdisciplinarities were found to be nearly independent from each other. These findings suggest that the notion of "interdisciplinarity" of a researcher should be understood as a multi-dimensional concept that should be evaluated using multiple assessment means.

  17. Characterizing interdisciplinarity of researchers and research topics using web search engines.

    Directory of Open Access Journals (Sweden)

    Hiroki Sayama

    Full Text Available Researchers' networks have been subject to active modeling and analysis. Earlier literature mostly focused on citation or co-authorship networks reconstructed from annotated scientific publication databases, which have several limitations. Recently, general-purpose web search engines have also been utilized to collect information about social networks. Here we reconstructed, using web search engines, a network representing the relatedness of researchers to their peers as well as to various research topics. Relatedness between researchers and research topics was characterized by visibility boost-increase of a researcher's visibility by focusing on a particular topic. It was observed that researchers who had high visibility boosts by the same research topic tended to be close to each other in their network. We calculated correlations between visibility boosts by research topics and researchers' interdisciplinarity at the individual level (diversity of topics related to the researcher and at the social level (his/her centrality in the researchers' network. We found that visibility boosts by certain research topics were positively correlated with researchers' individual-level interdisciplinarity despite their negative correlations with the general popularity of researchers. It was also found that visibility boosts by network-related topics had positive correlations with researchers' social-level interdisciplinarity. Research topics' correlations with researchers' individual- and social-level interdisciplinarities were found to be nearly independent from each other. These findings suggest that the notion of "interdisciplinarity" of a researcher should be understood as a multi-dimensional concept that should be evaluated using multiple assessment means.

  18. Thermal imaging to detect physiological indicators of stress in humans

    Science.gov (United States)

    Cross, Carl B.; Skipper, Julie A.; Petkie, Douglas T.

    2013-05-01

    Real-time, stand-off sensing of human subjects to detect emotional state would be valuable in many defense, security and medical scenarios. We are developing a multimodal sensor platform that incorporates high-resolution electro-optical and mid-wave infrared (MWIR) cameras and a millimeter-wave radar system to identify individuals who are psychologically stressed. Recent experiments have aimed to: 1) assess responses to physical versus psychological stressors; 2) examine the impact of topical skin products on thermal signatures; and 3) evaluate the fidelity of vital signs extracted from thermal imagery and radar signatures. Registered image and sensor data were collected as subjects (n=32) performed mental and physical tasks. In each image, the face was segmented into 29 non-overlapping segments based on fiducial points automatically output by our facial feature tracker. Image features were defined that facilitated discrimination between psychological and physical stress states. To test the ability to intentionally mask thermal responses indicative of anxiety or fear, subjects applied one of four topical skin products to one half of their face before performing tasks. Finally, we evaluated the performance of two non-contact techniques to detect respiration and heart rate: chest displacement extracted from the radar signal and temperature fluctuations at the nose tip and regions near superficial arteries to detect respiration and heart rates, respectively, extracted from the MWIR imagery. Our results are very satisfactory: classification of physical versus psychological stressors is repeatedly greater than 90%, thermal masking was almost always ineffective, and accurate heart and respiration rates are detectable in both thermal and radar signatures.

  19. Economic assessment of coal-burning locomotives: Topical report

    Energy Technology Data Exchange (ETDEWEB)

    1986-02-01

    The General Electric Company embarked upon a study to evaluate various alternatives for the design and manufacture a coal fired locomotive considering various prime movers, but retaining the electric drive transmission. The initial study was supported by the Burlington-Northern and Norfolk-Southern railroads, and included the following alternatives: coal fired diesel locomotive; direct fired gas turbine locomotives; direct fired gas turbine locomotive with steam injection; raw coal gasifier gas turbine locomotive; and raw coal fluid bed steam turbine locomotive. All alternatives use the electric drive transmission and were selected for final evaluation. The first three would use a coal water slurry as a fuel, which must be produced by new processing plants. Therefore, use of a slurry would require a significant plant capital investment. The last two would use classified run-of-the-mine (ROM) coal with much less capital expenditure. Coal fueling stations would be required but are significantly lower in capital cost than a coal slurry plant. For any coal fired locomotive to be commercially viable, it must pass the following criteria: be technically feasible and environmentally acceptable; meet railroads' financial expectations; and offer an attractive return to the locomotive manufacturer. These three criteria are reviewed in the report.

  20. Model-based assessment of the potential of seasonal aquifer thermal energy storage and recovery as a groundwater ecosystem service for the Brussels-Capital Region

    Science.gov (United States)

    Anibas, Christian; Huysmans, Marijke

    2015-04-01

    Urban areas are characterized by their concentrated demand of energy, applying a high pressure on urban ecosystems including atmosphere, soils and groundwater. In the light of global warming, urbanization and an evolving energy system, it is important to know how urbanized areas can contribute to their own energy demands. One option is to use the possibilities aquifers offer as an ecosystem service (BONTE et al., 2011). If used effectively an improvement in air and groundwater quality is achieved. Additionally, the more efficient distribution of the used energy may also lead to a decrease in primary energy consumption (ZUURBIER, 2013). Therefore, investigations of the potential of seasonal aquifer thermal energy storage and recovery (ATES) for the Brussels-Capital Region, Belgium is being conducted. The potential of ATES systems are of special interest for energy demands in high density urban areas because of such infrastructure as office buildings, schools, hospitals and shopping malls. In an open water circuit ATES systems consist of two or more groundwater wells, where in seasonal cycles one subtracts and the other recharges water to the aquifer. Heat pumps use the heat capacity of water for heating or cooling a building. An important limitation of the methodology is the quality of the groundwater used (i.e. precipitation of Fe- or Mn-oxides can decrease the yield). However, ATES systems on the other hand can also improve groundwater quality and groundwater ecosystems. The current knowledge of the potential for ATES systems in the Brussels-Capital Region is based on geological assessments from VITO (2007). The Brussels-Capital Region is divided into a western and eastern section with respect to geology. While the western part has less favorable conditions for ATES, the eastern is composed of the Brussels Sand formation, which is a 20-40 m thick aquifer layer that has the highest potential for ATES systems in the region. By applying groundwater flow and heat

  1. Thermal, Mechanical and Thermo-Mechanical Assessment of the Rock Mass Surrounding SKB's Prototype Repository at Äspö HRL

    Science.gov (United States)

    Lönnqvist, Margareta; Hökmark, Harald

    2016-04-01

    The Prototype Repository (PR) was a field test of six, electrically heated, full-scale waste containers resembling the key component of a KBS-3 nuclear waste repository. The design and heat load was similar to the proposed repository at Forsmark, Sweden. In this paper, the thermal, mechanical and thermo-mechanical response of the PR host rock to excavation and to the subsequent heating is assessed. The assessment is carried out using three-dimensional models (numerical and analytical) in combination with monitoring data and visual observations from the excavations. Certain measurements and observations agree well with results from the models. These include temperature measurements during the heating phase. Additional measurements include patterns of low-magnitude acoustic emission events around the deposition holes tracked during the excavation. The spatial distribution of these events coincide with regions of modelled high compressive stresses. Models with a simple fracture network, consisting of planar disks with laboratory-scale properties, appear to give upper bound estimates of the stress disturbances caused by a real fracture network. The magnitude of the modelled stresses around the deposition hole is typically below the spalling strength. The lack of any significant or systematic occurrence of spalling in the deposition hole walls supports the modelling results. Several instruments installed at different positions to monitor stress change, strain and deformation malfunctioned during the nearly 8-year-long monitoring period. Despite this, there is ample evidence to support the overall conclusion that the modelling results and observations are in sufficient agreement to strengthen the confidence in the modelling approach.

  2. A numerical approach to evaluating what percentage of a living space is well-ventilated, for the assessment of thermal comfort

    CERN Document Server

    Bastide, Alain; Garde, François; Boyer, Harry

    2012-01-01

    A bioclimatic approach to designing comfortable buildings in hot and humid tropical regions requires, firstly, some preliminary, important work on the building envelope to limit the energy contributions, and secondly, an airflow optimization of the building. For the first step, tools such as nodal or zonal models have been largely implemented. For the second step, the assessment of air velocities, in three dimensions and in a large space, can only be performed through the use of detailed models such as with CFD. This paper deals with the improvement of thermal comfort by ventilating around the occupants. For this purpose, the average velocity coefficient definition is modified to be adapted to CFD and the areas involving movement or the living spaces. We propose a new approach based on the derivation of a new quantity: the well-ventilated percentage of a living space. The well-ventilated percentage of a space allows a time analysis of the aeraulic behaviour of the building in its environment. These percentage...

  3. Assessment of groundwater pollution from ash ponds using stable and unstable isotopes around the Koradi and Khaperkheda thermal power plants (Maharashtra, India).

    Science.gov (United States)

    Voltaggio, M; Spadoni, M; Sacchi, E; Sanam, R; Pujari, P R; Labhasetwar, P K

    2015-06-15

    The impact on local water resources due to fly ash produced in the Koradi and Khaperkheda thermal power plants (district of Nagpur, Maharashtra - India) and disposed in large ponds at the surface was assessed through the study of environmental variation of ratios of stable and unstable isotopes. Analyses of oxygen and hydrogen isotopes suggest scarce interaction between the water temporarily stored in the ponds and the groundwater in the study area. Data also highlight that the high salinity of groundwater measured in the polluted wells is not due to evaporation, but to subsequent infiltration of stream waters draining from the ponds to the local aquifer. (87)Sr/(86)Sr values, when associated with Sr/Ca ratios, demonstrate the dominant role of waste waters coming from tens of brick kilns surrounding the pond sulfate pollution. Uranium isotopic analyses clearly show evidence of the interaction between groundwater and aquifer rocks, and confirm again the low influence of ash ponds. A new conceptual model based on the study of the isotopes of radium is also proposed and used to estimate residence times of groundwater in the area. This model highlights that high salinity cannot be in any case attributed to a prolonged water-rock interaction, but is due to the influence of untreated waste water of domestic or brick kiln origin on the shallow and vulnerable aquifers.

  4. FORESTS: BETWEEN ENERGY DEMAND AND ECOSYSTEM SERVICES. AN EMERGY ASSESSMENT OF FORESTRY STOCKS AS THE MAIN SOURCE OF THERMAL FUEL IN THE MARA RIVER WATERSHED, MARAMUREȘ COUNTY, ROMANIA

    Directory of Open Access Journals (Sweden)

    Silviu BUMBAK

    2016-09-01

    Full Text Available Nature builds resilience through storages of energy and one of the most iconic elements encompassing this capacity is represented by forests. Biomass in general and forests in particular are known to be one of the vast global reservoirs of carbon and energy and are described as forms of renewable natural capital that managed until the second half of the ninetieth century to globally sustain human communities as the major source of energy. Forests actively contribute to the functionality of a territorial system through a series of attributes such as water retention capacity, soil and slope stability, primary production capacity, all termed ecosystem services, benefits that communities take for granted. In more remote rural areas around the world, such as the Carpathian Mara River watershed, local communities still rely on forestry wood as the main supplier of thermal energy. The dependency relation also represents the community’s level of perception towards natural resources, the landmarks and image of the entire Land of Maramureș as „the wood civilisation”, for example, being a cultural construct build through this energetic resource. In a time of pressure over energetic resources and following the premises of Emergy Theory and methodology, in this paper we propose an alternative approach in assessing natural resources in order to better understand that the exploitable energetic value of forests comes second when compared with the value of the provided ecosystem services.

  5. A Survey of Topic Modeling in Text Mining

    Directory of Open Access Journals (Sweden)

    Rubayyi Alghamdi

    2015-01-01

    Full Text Available Topic models provide a convenient way to analyze large of unclassified text. A topic contains a cluster of words that frequently occur together. A topic modeling can connect words with similar meanings and distinguish between uses of words with multiple meanings. This paper provides two categories that can be under the field of topic modeling. First one discusses the area of methods of topic modeling, which has four methods that can be considerable under this category. These methods are Latent semantic analysis (LSA, Probabilistic latent semantic analysis (PLSA, Latent Dirichlet allocation (LDA, and Correlated topic model (CTM. The second category is called topic evolution models, which model topics by considering an important factor time. In the second category, different models are discussed, such as topic over time (TOT, dynamic topic models (DTM, multiscale topic tomography, dynamic topic correlation detection, detecting topic evolution in scientific literature, etc.

  6. STUDY ON USE OF TOPICAL DILTIAZEM VERSUS TOPICAL GLYCERYL TRINITRATE (GTN IN THE TREATMENT OF CHRONIC ANAL FISSURE: A RETROSPECTIVE STUDY

    Directory of Open Access Journals (Sweden)

    Madhu Lata

    2014-10-01

    Full Text Available OBJECTIVE: To compare the efficacy, associated side effects in short term as well as long term use of topical Diltiazem and topical GTN in the management of chronic anal fissure. MATERIAL AND METHODS: Out patients records of 231 patients with chronic anal fissure who reported to hospital from August 2011 to August 2014 and treated were randomly selected for both types of management of which 118 patients had received topical 2% diltiazem and 113 were treated with 0.2% glyceryl trinitrate topical ointment thrice daily for 6 weeks. They were assessed at the time of presentation, then at the end of 1st week, 3rd week and at the end of 6th week of treatment. Records of patients with anal fissure due to other diseases like inflammatory bowel disease, malignancy, sexually transmitted diseases, previous treatment with local ointment or surgery, patients who required anal surgery for any concurrent disease like hemorrhoids, pregnant women, patients with significant cardiovascular conditions and patients who did not turned up for follow up were excluded. Signs and symptoms and side-effects were noted at the given time. RESULTS: The study results are comparable to national figures and other studies. CONCLUSION: Topical application of both the ointments, 2% Diltiazem and 0.2% Glyceryl trinitrate observed to be quite effective in treatment of chronic fissure in Ano. However, topical Diltiazem is preferred to topical glyceryl trinitrate due to its lesser side effects and long term better control

  7. Thermal conveyance systems

    Energy Technology Data Exchange (ETDEWEB)

    Meador, J.T.

    1978-09-01

    The purpose of the evaluation is to characterize modern technology for long-distance, large-diameter, underground steam and high-temperature water (HTW) transport systems and for hot-water and chilled-water systems that distribute thermal energy within communities. Data on the status of existing systems have been compiled and compared with recommended design factors for fluid flow to aid in parameter selection for assessing performance in transporting and distributing thermal energy.

  8. TopicLens: Efficient Multi-Level Visual Topic Exploration of Large-Scale Document Collections.

    Science.gov (United States)

    Kim, Minjeong; Kang, Kyeongpil; Park, Deokgun; Choo, Jaegul; Elmqvist, Niklas

    2017-01-01

    Topic modeling, which reveals underlying topics of a document corpus, has been actively adopted in visual analytics for large-scale document collections. However, due to its significant processing time and non-interactive nature, topic modeling has so far not been tightly integrated into a visual analytics workflow. Instead, most such systems are limited to utilizing a fixed, initial set of topics. Motivated by this gap in the literature, we propose a novel interaction technique called TopicLens that allows a user to dynamically explore data through a lens interface where topic modeling and the corresponding 2D embedding are efficiently computed on the fly. To support this interaction in real time while maintaining view consistency, we propose a novel efficient topic modeling method and a semi-supervised 2D embedding algorithm. Our work is based on improving state-of-the-art methods such as nonnegative matrix factorization and t-distributed stochastic neighbor embedding. Furthermore, we have built a web-based visual analytics system integrated with TopicLens. We use this system to measure the performance and the visualization quality of our proposed methods. We provide several scenarios showcasing the capability of TopicLens using real-world datasets.

  9. Analyses of Research Topics in the Field of Informetrics Based on the Method of Topic Modeling

    Directory of Open Access Journals (Sweden)

    Sung-Chien Lin

    2014-07-01

    Full Text Available In this study, we used the approach of topic modeling to uncover the possible structure of research topics in the field of Informetrics, to explore the distribution of the topics over years, and to compare the core journals. In order to infer the structure of the topics in the field, the data of the papers published in the Journal of Informetricsand Scientometrics during 2007 to 2013 are retrieved from the database of the Web of Science as input of the approach of topic modeling. The results of this study show that when the number of topics was set to 10, the topic model has the smallest perplexity. Although data scopes and analysis methodsare different to previous studies, the generating topics of this study are consistent with those results produced by analyses of experts. Empirical case studies and measurements of bibliometric indicators were concerned important in every year during the whole analytic period, and the field was increasing stability. Both the two core journals broadly paid more attention to all of the topics in the field of Informetrics. The Journal of Informetricsput particular emphasis on construction and applications ofbibliometric indicators and Scientometrics focused on the evaluation and the factors of productivity of countries, institutions, domains, and journals.

  10. Topical treatment options for conjunctival neoplasms

    Directory of Open Access Journals (Sweden)

    Jonathan W Kim

    2008-10-01

    Full Text Available Jonathan W Kim, David H AbramsonOphthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USAAbstract: Topical therapies offer a nonsurgical method for treating conjunctival tumors by delivering high drug concentrations to the ocular surface. Over the past ten years, topical agents have been used by investigators to treat various premalignant and malignant lesions of the conjunctiva, such as primary acquired melanosis with atypia, conjunctival melanoma, squamous intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva, and pagetoid spread of the conjunctiva arising from sebaceous cell carcinoma. Despite the enthusiasm generated by the success of these agents, there are unanswered questions regarding the clinical efficacy of this new nonsurgical approach, and whether a single topical agent can achieve cure rates comparable with traditional therapies. Furthermore, the long-term consequences of prolonged courses of topical chemotherapeutic drugs on the ocular surface are unknown, and the ideal regimen for each of these agents is still being refined. In this review, we present specific guidelines for treating both melanocytic and squamous neoplasms of the conjunctiva, utilizing the available data in the literature as well as our own clinical experience at the Memorial Sloan-Kettering Cancer Center.Keywords: topical therapies, conjunctival neoplasms melanosis, Mitomycin-C, 5-Fluorouracil

  11. Heat transfer, thermal control, and heat pipes

    Science.gov (United States)

    Olstad, W. B.

    1980-01-01

    This volume provides information on recent progress in spacecraft thermal control and the supporting disciplines of conduction, thermal radiation, and heat pipe theory and application. Four problem areas are considered: conduction heat transfer, radiation heat transfer, thermal control, and heat pipes. The topics covered include finite-element methodology for transient conduction/forced-convection thermal analysis; effects of surface finish on thermal contact resistance between different materials; mathematical models for wide-band nongray gas radiation in spherical and cylindrical geometries; thermal design, analysis and testing of the Shuttle remote manipulator arm; porous heat pipe; and transient behavior of liquid trap heat-pipe thermal diodes. Also discussed is the thermal design concept for a high-resolution UV spectrometer.

  12. The effects of topical Arnica on performance, pain and muscle damage after intense eccentric exercise.

    Science.gov (United States)

    Pumpa, Kate L; Fallon, Kieran E; Bensoussan, Alan; Papalia, Shona

    2014-01-01

    The aim of the study was to determine if topical Arnica is effective in reducing pain, indicators of inflammation and muscle damage, and in turn improve performance in well-trained males experiencing delayed onset muscle soreness (DOMS). Twenty well-trained males matched by maximal oxygen uptake (V̇O2 Max) completed a double-blind, randomised placebo-controlled trial. Topical Arnica was applied to the skin superficial to the quadriceps and gastrocnemius muscles immediately after a downhill running protocol designed to induce DOMS. Topical Arnica was reapplied every 4 waking hours for the duration of the study. Performance measures (peak torque, countermovement and squat jump), pain assessments (visual analogue scale (VAS) and muscle tenderness) and blood analysis (interleukin-1 beta, interleukin-6, tumour necrosis factor-alpha, C-reactive protein, myoglobin and creatine kinase) were assessed at seven time points over five days (pre-, post-, 4, 24, 48, 72 and 96 hours after the downhill run). Participants in the topical Arnica group reported less pain as assessed through muscle tenderness and VAS 72 hours post-exercise. The application of topical Arnica did not affect any performance assessments or markers of muscle damage or inflammation. Topical Arnica used immediately after intense eccentric exercise and for the following 96 hours did not have an effect on performance or blood markers. It did however demonstrate the possibility of providing pain relief three days post-eccentric exercise.

  13. Response to comments received from the State of Colorado and the public on the Environmental Assessment for resumption of thermal stabilization of plutonium oxide in Building 707

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Department of Energy (DOE) prepared this document to respond to comments from the State of Colorado and the public on the draft Environmental Assessment (EA) for the Resumption of Thermal Stabilization of Plutonium Oxide in Building 707 at the Rocky Flats Plant (RFP) in Golden, Colorado. The draft EA was provided to the State of Colorado and the public on September 8, 1993, for a comment period of 60 days. The Department`s National Environmental Policy Act (NEPA) Implementing Procedures (10 Code of Federal Regulations [CFR] 1021.301) requires that prior to approval of the EA, DOE is to allow the host State and Indian Tribe a period of from 14 to 30 days to review and comment on the EA. The Department established a comment period of 60 days for this EA in response to requests by the public during the first public meeting on July 7, 1993, before preparation of the EA. Other issues raised at the July 7 meeting included the range of alternatives to be considered, the time period for preparation of the EA, and the amount of material to be thermally stabilized. These and other comments made by the public at that meeting were carefully considered in preparation of the EA. In addition to providing the preapproval draft EA to the State of Colorado, DOE distributed the EA to all persons and groups on the RFP public information mailing list and placed the EA and reference documents in the DOE Public Reading Rooms in the RFP area. A public meeting was held on October 6, 1993, to hear public comments on the draft EA. All comments on the draft EA, those received both at the October 6 public meeting and through correspondence, have been reproduced in their entirety in this Response to Comments document. Responses to the commenters` questions and concerns are provided, and changes made to the body of the EA are indicated in the responses. All comments received have been considered in the revision of the EA.

  14. Automated Word Puzzle Generation via Topic Dictionaries

    CERN Document Server

    Pinter, Balazs; Szabo, Zoltan; Lorincz, Andras

    2012-01-01

    We propose a general method for automated word puzzle generation. Contrary to previous approaches in this novel field, the presented method does not rely on highly structured datasets obtained with serious human annotation effort: it only needs an unstructured and unannotated corpus (i.e., document collection) as input. The method builds upon two additional pillars: (i) a topic model, which induces a topic dictionary from the input corpus (examples include e.g., latent semantic analysis, group-structured dictionaries or latent Dirichlet allocation), and (ii) a semantic similarity measure of word pairs. Our method can (i) generate automatically a large number of proper word puzzles of different types, including the odd one out, choose the related word and separate the topics puzzle. (ii) It can easily create domain-specific puzzles by replacing the corpus component. (iii) It is also capable of automatically generating puzzles with parameterizable levels of difficulty suitable for, e.g., beginners or intermedia...

  15. Getting Started with Topic Modeling and MALLET

    Directory of Open Access Journals (Sweden)

    Shawn Graham

    2012-09-01

    Full Text Available In this lesson you will first learn what topic modeling is and why you might want to employ it in your research. You will then learn how to install and work with the MALLET natural language processing toolkit to do so. MALLET involves modifying an environment variable (essentially, setting up a short-cut so that your computer always knows where to find the MALLET program and working with the command line (ie, by typing in commands manually, rather than clicking on icons or menus. We will run the topic modeller on some example files, and look at the kinds of outputs that MALLET installed. This will give us a good idea of how it can be used on a corpus of texts to identify topics found in the documents without reading them individually.

  16. Lecture Notes on Topics in Accelerator Physics

    CERN Document Server

    Chao, A W

    2002-01-01

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures is not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others.

  17. Topical and peripheral ketamine as an analgesic.

    Science.gov (United States)

    Sawynok, Jana

    2014-07-01

    Ketamine, in subanesthetic doses, produces systemic analgesia in chronic pain settings, an action largely attributed to block of N-methyl-D-aspartate receptors in the spinal cord and inhibition of central sensitization processes. N-methyl-D-aspartate receptors also are located peripherally on sensory afferent nerve endings, and this provided the initial impetus for exploring peripheral applications of ketamine. Ketamine also produces several other pharmacological actions (block of ion channels and receptors, modulation of transporters, anti-inflammatory effects), and while these may require higher concentrations, after topical (e.g., as gels, creams) and peripheral application (e.g., localized injections), local tissue concentrations are higher than those after systemic administration and can engage lower affinity mechanisms. Peripheral administration of ketamine by localized injection produced some alterations in sensory thresholds in experimental trials in volunteers and in complex regional pain syndrome subjects in experimental settings, but many variables were unaltered. There are several case reports of analgesia after topical application of ketamine given alone in neuropathic pain, but controlled trials have not confirmed such effects. A combination of topical ketamine with several other agents produced pain relief in case, and case series, reports with response rates of 40% to 75% in retrospective analyses. In controlled trials of neuropathic pain with topical ketamine combinations, there were improvements in some outcomes, but optimal dosing and drug combinations were not clear. Given orally (as a gargle, throat swab, localized peritonsillar injections), ketamine produced significant oral/throat analgesia in controlled trials in postoperative settings. Topical analgesics are likely more effective in particular conditions (patient factors, disease factors), and future trials of topical ketamine should include a consideration of factors that could predispose

  18. Underground Coal Thermal Treatment

    Energy Technology Data Exchange (ETDEWEB)

    Smith, P. [Univ. of Utah, Salt Lake City, UT (United States); Deo, M. [Univ. of Utah, Salt Lake City, UT (United States); Eddings, E. [Univ. of Utah, Salt Lake City, UT (United States); Sarofim, A. [Univ. of Utah, Salt Lake City, UT (United States); Gueishen, K. [Univ. of Utah, Salt Lake City, UT (United States); Hradisky, M. [Univ. of Utah, Salt Lake City, UT (United States); Kelly, K. [Univ. of Utah, Salt Lake City, UT (United States); Mandalaparty, P. [Univ. of Utah, Salt Lake City, UT (United States); Zhang, H. [Univ. of Utah, Salt Lake City, UT (United States)

    2012-01-11

    The long-term objective of this work is to develop a transformational energy production technology by insitu thermal treatment of a coal seam for the production of substitute natural gas (SNG) while leaving much of the coal's carbon in the ground. This process converts coal to a high-efficiency, low-GHG emitting gas fuel. It holds the potential of providing environmentally acceptable access to previously unusable coal resources. This topical report discusses the development of experimental capabilities, the collection of available data, and the development of simulation tools to obtain process thermo-chemical and geo-thermal parameters in preparation for the eventual demonstration in a coal seam. It also includes experimental and modeling studies of CO2 sequestration.

  19. Successful treatment of periungual warts with topical cidofovir.

    Science.gov (United States)

    Padilla España, Laura; Del Boz, Javier; Fernández Morano, Teresa; Arenas-Villafranca, Javier; de Troya, Magdalena

    2014-01-01

    Periungual warts represent a treatment challenge because of its high recurrence rate and recalcitrance. These are benign lesions produced by the human papilloma virus (HPV) that often do not respond to habitual treatment. Cidofovir is a potent antiviral drug that acts inactivating viral DNA polymerase. Topical cidofovir for the treatment of HPV-related cutaneous and mucous lesions is becoming increasingly common. Our aim was to assess the efficacy and safety of cidofovir cream for the treatment of viral periungual warts. We undertook a retrospective observational study of patients with periungual warts who received treatment with topical cidofovir between January 2010 and December 2013 at the Dermatology Service of the Hospital Costa del Sol, Marbella, Spain. Data were recorded about the rate of treatment response, the adverse effects and recurrences, as well as the characteristics of the patient cohort. We identified 41 patients who had received some previous treatment. The concentration of cidofovir was 3% in all cases, usually applied twice a day (in 37 of the 41 cases). A greater or lesser response was noted in 35 cases. There were six recurrences in the follow-up period. Topical cidofovir seems to be a useful alternative for the therapeutic management of recalcitrant periungual common warts that fail to respond to usual treatment. Our experience with the use of this antiviral agent has been satisfactory, although in our opinion, it should be reserved for specific cases as its economical cost represents an important limitation.

  20. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  1. Illustrative EDOF topics in Fourier optics

    Science.gov (United States)

    George, Nicholas; Chen, Xi; Chi, Wanli

    2011-10-01

    In this talk we present a series of illustrative topics in Fourier Optics that are proving valuable in the design of EDOF camera systems. They are at the level of final examination problems that have been made solvable by a student or professoi having studied from one of Joseph W. Goodman's books---our tribute for his 75fr year. As time permits, four illustrative topics are l) Electromagnetic waves and Fourier optics;2) The perfect lens; 3) Connection between phase delay and radially varying focal length in an asphere and 4) tailored EDOF designs.

  2. Topical therapy in atopic dermatitis in children

    Directory of Open Access Journals (Sweden)

    Dharshini Sathishkumar

    2016-01-01

    Full Text Available Atopic dermatitis (AD is a common, chronic childhood skin disorder caused by complex genetic, immunological, and environmental interactions. It significantly impairs quality of life for both child and family. Treatment is complex and must be tailored to the individual taking into account personal, social, and emotional factors, as well as disease severity. This review covers the management of AD in children with topical treatments, focusing on: education and empowerment of patients and caregivers, avoidance of trigger factors, repair and maintenance of the skin barrier by correct use of emollients, control of inflammation with topical corticosteroids and calcineurin inhibitors, minimizing infection, and the use of bandages and body suits.

  3. Topic Time Series Analysis of Microblogs

    Science.gov (United States)

    2014-10-01

    does not display a currently valid OMB control number. 1. REPORT DATE OCT 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE...Tweets in topic k triggered by a Tweet in topic k, also known as the branching factor. ωk is a parameter controlling the rate of decay, i.e. how...2011. [20] Yosihiko Ogata . Statistical models for earthquake occurrences and residual analysis for point pro- cesses. Journal of the American

  4. Safety of topical vancomycin powder in neurosurgery

    Directory of Open Access Journals (Sweden)

    Kalil G Abdullah

    2016-01-01

    Full Text Available Surgical site infections (SSIs remain an important cause of morbidity following neurosurgical procedures despite the best medical practices. In addition, hospital infection rates are proposed as a metric for ranking hospitals safety profiles to guide medical consumerism. Recently, the use of topical vancomycin, defined as the application of vancomycin powder directly into the surgical wound, has been described in both cranial and spinal surgeries as a method to reduce SSIs. Early results are promising. Here, we provide a concise primer on the pharmacology, bacterial spectrum, history, and clinical indications of topical vancomycin for the practicing surgeon.

  5. Applied atomic and collision physics special topics

    CERN Document Server

    Massey, H S W; Bederson, Benjamin

    1982-01-01

    Applied Atomic Collision Physics, Volume 5: Special Topics deals with topics on applications of atomic collisions that were not covered in the first four volumes of the treatise. The book opens with a chapter on ultrasensitive chemical detectors. This is followed by separate chapters on lighting, magnetohydrodynamic electrical power generation, gas breakdown and high voltage insulating gases, thermionic energy converters, and charged particle detectors. Subsequent chapters deal with the operation of multiwire drift and proportional chambers and streamer chambers and their use in high energy p

  6. Heart block following topical latanoprost treatment

    Science.gov (United States)

    De Smit, Elisabeth; Theodorou, Maria; Hildebrand, Göran Darius; Bloom, Philip

    2011-01-01

    The authors report a case of second degree heart block associated with topical latanoprost treatment. The authors discuss the possibility of a causative effect as the cessation of this treatment resulted in improvement of the arrhythmia. The authors highlight previous reports and research in humans and animals which demonstrate an association of arrhythmias with prostaglandin analogues. This report draws attention to the possibility that an extremely commonly prescribed topical drug may trigger arrhythmias in susceptible individuals. It is important that prescribers are aware of this possible side-effect. PMID:22679164

  7. Aceclofenac topical dosage forms: in vitro and in vivo characterization.

    Science.gov (United States)

    Dua, Kamal; Pabreja, Kavita; Ramana, Malipeddi Venkata

    2010-12-01

    Aceclofenac is a new generation non-steroidal anti-inflammatory drug showing effective anti-inflammatory and analgesic properties. It is available in the form of tablets of 100 mg. Importance of aceclofenac as a NSAID has inspired development of topical dosage forms. This mode of administration may help avoid typical side effects associated with oral administration of NSAIDs, which have led to its withdrawal. Furthermore, aceclofenac topical dosage forms can be used as a supplement to oral therapy for better treatment of conditions such as arthritis. Ointments, creams, and gels containing 1% (m/m) aceclofenac have been prepared. They were tested for physical appearance, pH, spreadability, extrudability, drug content uniformity, in vitro diffusion and in vitro permeation. Gels prepared using Carbopol 940 (AF2, AF3) and macrogol bases (AF7) were selected after the analysis of the results. They were evaluated for acute skin irritancy, anti-inflammatory and analgesic effects using the carrageenan-induced thermal hyperalgesia and paw edema method. AF2 was shown to be significantly (p < 0.05) more effective in inhibiting hyperalgesia associated with inflammation, compared to AF3 and AF7. Hence, AF2 may be suggested as an alternative to oral preparations.

  8. Topics and features of academic medical library tutorials.

    Science.gov (United States)

    Anderson, Rozalynd P; Wilson, Steven P; Yeh, Felicia; Phillips, Betty; Livingston, Mary Briget

    2008-01-01

    In a 2007 study, librarians at the University of South Carolina School of Medicine Library examined freely available online tutorials on academic medical library Web sites. The team identified tutorial topics, determined common design features, and assessed elements of active learning in library-created tutorials; the team also generated a list of third-party tutorials to which medical libraries link. This article updates the earlier study, describing changes and trends in tutorial content and design on medical libraries' Web sites; the project team plans to continue to track trends in tutorial development by repeating this study annually.

  9. Aortic regurgitation and extracorporeal membrane oxygenation: An undiscussed topic

    Directory of Open Access Journals (Sweden)

    Fabrizio Sansone

    2012-01-01

    Full Text Available The aim of this short discussion is to open the question of the AR in case of ECMO implantation. This is the case of a young male admitted to the hospital for acute cardiac failure in chronic dilated cardio-myopathy due to aortic regurgitation (AR: the patient had previously refused aortic valve replacement (AVR for the fear of postoperative outcome. Further studies are required to assess this topic and the perspectives to increase the use of the peripheral ECMO and the percutaneous ventricular venting through the interatrial septum may be of interest to improve the outcome of such ill patients.

  10. Aortic regurgitation and extracorporeal membrane oxygenation:An undiscussed topic

    Institute of Scientific and Technical Information of China (English)

    Fabrizio Sansone

    2012-01-01

    The aim of this short discussion is to open the question of the AR in case of ECMO implantation. This is the case of a young male admitted to the hospital for acute cardiac failure in chronic dilated cardio-myopathy due to aortic regurgitation (AR): the patient had previously refused aortic valve replacement (AVR) for the fear of postoperative outcome. Further studies are required to assess this topic and the perspectives to increase the use of the peripheral ECMO and the percutaneous ventricular venting through the interatrial septum may be of interest to improve the outcome of such ill patients.

  11. Using Factor Analysis to Identify Topic Preferences Within MBA Courses

    Directory of Open Access Journals (Sweden)

    Earl Chrysler

    2003-02-01

    Full Text Available This study demonstrates the role of a principal components factor analysis in conducting a gap analysis as to the desired characteristics of business alumni. Typically, gap analyses merely compare the emphases that should be given to areas of inquiry with perceptions of actual emphases. As a result, the focus is upon depth of coverage. A neglected area in need of investigation is the breadth of topic dimensions and their differences between the normative (should offer and the descriptive (actually offer. The implications of factor structures, as well as traditional gap analyses, are developed and discussed in the context of outcomes assessment.

  12. An Exploratory Study into Perceived Task Complexity, Topic Specificity and Usefulness for Integrated Search

    DEFF Research Database (Denmark)

    Ingwersen, Peter; Lioma, Christina; Larsen, Birger

    2012-01-01

    We investigate the relations between user perceptions of work task complexity, topic specificity, and usefulness of retrieved results. 23 academic researchers submitted detailed descriptions of 65 real-life work tasks in the physics domain, and assessed documents retrieved from an integrated...... collection consisting of full text research articles in PDF, abstracts, and bibliographic records [6]. Bibliographic records were found to be more precise than full text PDFs, regardless of task complexity and topic specificity. PDFs were found to be more useful. Overall, for higher task complexity and topic...

  13. 75 FR 26647 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2010-05-12

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 524 Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution AGENCY: Food and Drug Administration, HHS. ACTION: Final rule, technical amendment. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug...

  14. 76 FR 81806 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2011-12-29

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 524 Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...

  15. The role of quantum information in thermodynamics—a topical review

    Science.gov (United States)

    Goold, John; Huber, Marcus; Riera, Arnau; del Rio, Lídia; Skrzypczyk, Paul

    2016-04-01

    This topical review article gives an overview of the interplay between quantum information theory and thermodynamics of quantum systems. We focus on several trending topics including the foundations of statistical mechanics, resource theories, entanglement in thermodynamic settings, fluctuation theorems and thermal machines. This is not a comprehensive review of the diverse field of quantum thermodynamics; rather, it is a convenient entry point for the thermo-curious information theorist. Furthermore this review should facilitate the unification and understanding of different interdisciplinary approaches emerging in research groups around the world.

  16. Estimating method of the complexity of topics of school physics course

    Directory of Open Access Journals (Sweden)

    Robert Maier

    2014-06-01

    Full Text Available The author suggests the technique of the content analysis of various topics of school course of the physics. It is based on definition of the following indicators: 1 complexity of the physical objects, represented on drawings; 2 complexity of used physical models. The corresponding scales are developed, the assessment of physical complexity of 27 subjects is made, and topics with high and low level of complexity are revealed.

  17. The topical corticosteroid classification called into question: towards a new approach.

    Science.gov (United States)

    Humbert, Philippe; Guichard, Alexandre

    2015-05-01

    Vasoconstrictor assay described in 1962 was an interesting assessment of potency of topical corticosteroids at the beginning of these new therapies, however knowledge and technology have evolved and the classification should follow. A topical corticosteroids with a strong vasoconstrictor effect, as determined by vasoconstrictor assay, has not necessary a strong anti-inflammatory effect. Therefore a specific classification adapted to the therapeutic target is needed to be more efficient and thus reduce side effects and corticophobia.

  18. Vermicular cast iron production in the “Inmold” technology (in the Metalpol casting house and the assessment of its thermal fatigue resistance

    Directory of Open Access Journals (Sweden)

    J. Zych

    2011-07-01

    Full Text Available The method of obtaining the vermicular cast iron in the “Inmold” technology and the results of the thermal fatigue investigations, are presented in the paper. The influence of the maximum cycle temperature (Tmax on the thermal fatigue resistance was examined by means of the L.F. Coffin method. The cast iron structure change caused by the thermal fatigue is presented in the paper. When the vermicular cast iron is subjected to the thermal fatigue the matrix ferritisation occurs, which leads to the strength, Rm., decrease. The heating process of the vermicular cast iron is slower as compared to the spheroidal cast iron, whereas the cooling process is faster. Under the same conditions of heat exchanging the vermicular cast iron is heated to a much lower temperature than the spheroidal one. Together with the maximum heating temperature increase the thermal fatigue resistance decreases.

  19. Comprehensive assessment of the effective scope of modernization of thermal power plants to substantiate the rational structure of the generating capacities for the future until 2035

    Science.gov (United States)

    Veselov, F. V.; Erokhina, I. V.; Makarova, A. S.; Khorshev, A. A.

    2017-03-01

    The article deals with issues of technical and economic substantiation of priorities and scopes of modernizing the existing thermal power plants (TPPs) in Russia to work out long-term forecasts of the development of the industry. The current situation in the TPP modernization trends is analyzed. The updated initial figures of the capital and operation costs are presented and the obtained estimates of the comparative efficiency of various investment decisions on modernization and equipment replacement at gas-and-oil-burning and coal-fired TPPs with regard to the main zones of the national Unified Power System (UPS) of Russia are cited. The results of optimization of the generating capacity structure underlie a study of alternative TPP modernization strategies that differ in the scope of switching to new technologies, capital intensity, and energy efficiency (decrease in the average heat rate). To provide an integral economic assessment of the above strategies, the authors modified the traditional approach based on determination of the overall discounted costs of power supply (least-cost planning) supplemented with a comparison by the weighted average wholesale price of the electricity. A method for prediction of the wholesale price is proposed reasoning from the direct and dual solutions of the optimization problem. The method can be adapted to various combinations of the mechanisms of payment for the electricity and the capacity on the basis of marginal and average costs. Energy and economic analysis showed that the opposite effects of reduction in the capital investment and fuel saving change in a nonlinear way as the scope of the switch to more advanced power generation technologies at the TPPs increases. As a consequence, a strategy for modernization of the existing power plants rational with respect to total costs of the power supply and wholesale electricity prices has been formulated. The strategy combines decisions on upgrade and replacement of the equipment

  20. The use of thermal imaging to assess the effectiveness of ice massage and cold-water immersion as methods for supporting post-exercise recovery.

    Science.gov (United States)

    Adamczyk, Jakub Grzegorz; Krasowska, Ilona; Boguszewski, Dariusz; Reaburn, Peter

    2016-08-01

    Cold water immersion (CWI) and ice massage (IM) are commonly used treatments to prevent the delay onset of muscle soreness (DOMS); however, little is known on their relative benefits and effectiveness to lower tissue temperature. This study was designed to evaluate the effectiveness of IM and CMI on tissue temperature and potential benefit to preventing DOMS. The research encompassed 36 subjects divided into three groups of twelve depending on the form of recovery: ice massage (IM), cold-water immersion (CWI), or passive recovery (PAS). All the participants were asked to jump as high as possible from a full squat for one minute. Thermal imaging was conducted at rest, immediately following the exercise, immediately after the trial, following the recovery treatment, and after 30min of rest. Their pain levels were assessed using the Visual Analogue Scale (VAS). After applying the selected method for supporting recovery, the LA level decreased by 4.25mmol/L in the IM group, and by 4.96mmol/L in the CWI group (IM vs. CWI p>0.05). The 2.75mmol/L decrease in lactate concentration in the PAS group was significantly lower than in the other groups (IM vs. PAS p0.05). Seventy-two hours after the exercise, a clear decrease in discomfort was observed in the IM and CWI groups compared to the PAS group. The two applied treatments have proven to be effective both in utilizing lactate and preventing DOMS. Depending on training requirements, we recommend the use of IM when athletes experience localized muscle fatigue. One the other hand, CWI is recommended in situations of global or generalized muscle injury or fatigue.