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Sample records for assessment study pts

  1. TRAC analysis and support of Oconee-1 PTS studies

    International Nuclear Information System (INIS)

    This paper describes the overall pressurized thermal shock (PTS) program at Los Alamos with emphasis on TRAC-PF1 calculations of severe overcooling transients for the Oconee-1 pressurized water reactor (PWR). A summary of results for several calculations are presented for the Oconee-1 PWR along with detailed discussions of two of the most severe overcooling transients predicted [main steam-line break and turbine-bypass valve (TBV) failures]. The calculations performed were plant specific in that details of both the primary and secondary sides were modeled in addition to a detailed model of the plant Integrated Control System (ICS). For the Oconee-1 main steam-line break transient, a minimum downcomer fluid temperature of approx. 405 K was predicted. For the TBV transient involving the failure of one bank of TBVs to close after initially opening following reactor and turbine trips, an extrapolated downcomer fluid temperature of approx. 365 K was estimated. The latter temperature is at the nil-ductility temperature (NDT) limit (approx. 365 K) for Oconee-1

  2. Transferability of results of PTS experiments to the integrity assessment of reactor pressure vessels

    International Nuclear Information System (INIS)

    The integrity assessment of the reactor pressure vessel (RPV) is based on the fracture mechanics concept as provided in the code. However this concept covers only the linear-elastic fracture mechanics regime on the basis of the reference temperature RTNDT as derived from charpy impact and drop-weight test. The conservatism of this concept was demonstrated for a variety of different materials covering optimized and lower bound material states with regard to unirradiated and irradiated conditions. For the elastic-plastic regime, methodologies have been developed to describe ductile crack initiation and stable crack growth. The transferability of both, the linear-elastic and elastic-plastic fracture mechanics concept was investigated with the help of large scale specimens focusing on complex loading situations as they result from postulated thermal shock events for the RPV. A series of pressurized thermal shock (PTS) experiments were performed in which the applicability of the fracture mechanics parameters derived from small scale specimen testing could be demonstrated. This includes brittle (static and dynamic) crack initiation and crack arrest in the low charpy energy regime as well as stable crack initiation, stable crack growth and crack arrest in the upper shelf toughness regime. The paper provides the basic material data, the load paths, representative for large complex components as well as experimental and theoretical results of PTS experiments. From these data it can be concluded that the available fracture mechanics concepts can be used to describe the component behavior under transient loading conditions. (author). 26 refs, 12 figs, 1 tab

  3. Mechanism of phosphoryl transfer and protein-protein interaction in the PTS system-an NMR study

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopal, P.; Klevit, R.E. [Univ. of Washington, Seattle, WA (United States)

    1994-12-01

    HPr and Enzyme IIA{sup Glc} are two of the components of the bacterial PTS (phosphoenolpyruvate: sugar phosphotranferase system) and are involved in the phosphorylation and concomitant translocation of sugars across the membrane. These PTS protein complexes also regulate sugar transport. HPr, phosphorylated at a histidine N1 site by Enzyme I and phosphoenol pyruvate, transfers the phosphoryl group to a histidine N3 position in Enzyme IIA{sup Glc}. HPrs from Gram-positive bacteria undergo regulatory phosphorylation at Ser{sup 46}, whereby phosphorylation of the histidine residue is inhibited. Conversely, histidine phosphorylation inhibits phosphorylation at Ser{sup 46}. HPrs from Gram-negative bacteria possess a serine residue at position 46, but do not undergo regulatory phosphorylation. HPr forms an open-faced sandwich structure with a four-strand S-sheet and 2 to 3 helices lying on top of the sheet. The active-site histidine and Ser{sup 46} occur in conformationally flexible regions. P-His-HPr from the Gram-positive bacterium Bacillus subtilus has been investigated by both homonuclear and heteronuclear two-dimensional and three-dimensional NMR experiments using an in-situ enzymatic regeneration system to maintain a constant level of P-His-HPr. The results show that localized conformational changes occur in the vicinity of the active-site histidine and also near Ser{sup 46}. HPr-Enzyme IIA{sup Glc} complexes from both Bacillus subtilis and Gram-negative Escherichia coli were also studied by a variety of {sup 15}N-edited two-dimensional NMR experiments, which were performed on uniformly {sup 15}N-labeled HPr complexed to unlabeled Enzyme IIA{sup Glc}. The complex is in fast exchange with a molecular weight of about 27 kDa. The focus of our work is to assess the changes undergone by HPr (the smaller of the two components), and so all the experiments were performed with excess Enzyme IIA present in the system.

  4. ASSESSMENT OF BONE TISSUE CONDITION BY METHOD OF COMPUTED TOMOGRAPHY IN PTS WITH RHEUMATOID ARTHRITIS

    Directory of Open Access Journals (Sweden)

    T A Raskina

    2002-01-01

    Full Text Available Aim: To estimate the bone mineral density (BMD in patients with dilVerent variants of rheumatoid arthritis (RA. Materials and methods: The study included 65 patients with the acknowledged RA, who were not treated with corticosteroids, basic remedies and antiosteoporosis therapies. The group comprises 26 women оГ reproductive age (I group and 28 women in postmenopause period. The investigations were held with the computer tomograph “Tomoscan” Philips. Results: The comparative analysis of BMD disorders frequency in the studied groups shows that in RA women of postmenopause period osteopenia accounts for 57,1%, osteoporosis - for 32,1% of patients, which is twice as often as in premenopausal women period: 30,8% and 15,4% respectively. BMD levels in RA are correlated with rheumatoid lactor, destructive tendency in bones and high activity of disease.

  5. Mechanical study of the Saclay piezo tuner PTS (piezo tuning system) Care-SRF-WP8

    Energy Technology Data Exchange (ETDEWEB)

    Bosland, P.; Wu, B

    2005-03-15

    The present tuner is working inside Tesla test facility's cryo-modules without any piezo actuator. Thus the Lorentz force detuning in the pulsed mode of the accelerator is limiting the maximum accelerating field of cavity at about 25 MV/m. Previous studies and tests have demonstrated that the integration of piezo actuators in the tuner can lead to the compensation of the Lorentz force detuning at field higher than 35 MV/m. Our goal is now to develop and optimize a new tuner integrating piezo actuators. The mechanical studies are now finished and fabrication is in progress. This report presents the principle of this new system, its design and reviews the cavity frequency shifts during preparation process and assesses the forces applied by the cavity on the piezo actuators. (A.C.)

  6. Current pulse shaping of the load current on PTS

    Science.gov (United States)

    Xia, Minghe; Li, Fengping; Ji, Ce; Wei, Bing; Feng, Shuping; Wang, Meng; Xie, Weiping

    2016-02-01

    The typical rise time of PTS machine is ˜110 ns with about 10 MA peak current under short pulse mode when all 24 modules discharge simultaneously. By distributing the trigger times of 12 laser beams logically and adjusting the statues of the pulse output switches, longer rise-time pulse can be obtained on the PTS facility. Based on the required pulse shape, whole circuit simulations will be used to calculate the trigger times of each laser triggering gas switch and the status of the pulse output switches. The rise time of the current is determined by the time difference between the first and last trigged laser triggering gas switches. In order to trigger the laser triggering gas switch, sufficient laser power is needed to be sent into the gap of the gas switches. The gas pressure and voltage difference on the two electrodes of the gas switches also affect the triggering of the gas switches, and the voltage added on the gas switch is determined by its transition time. Traditionally the trigger time difference should be less than the transition time of the two neighboring modules. A new simulation model of PTS shows one can break this transition time limits. Series of current pulse shaping experiments have been investigated on the PTS (Primary Test Stand). As results, more than 5 MA peak current were successfully achieved on the load with a rise time of 600 ns. This study and experiments of the pulse shaping on PTS demonstrate the adaptable ability of the PTS for offering different waveform of mega ampere current pulse for different research purpose.

  7. Current pulse shaping of the load current on PTS

    Directory of Open Access Journals (Sweden)

    Minghe Xia

    2016-02-01

    Full Text Available The typical rise time of PTS machine is ∼110 ns with about 10 MA peak current under short pulse mode when all 24 modules discharge simultaneously. By distributing the trigger times of 12 laser beams logically and adjusting the statues of the pulse output switches, longer rise-time pulse can be obtained on the PTS facility. Based on the required pulse shape, whole circuit simulations will be used to calculate the trigger times of each laser triggering gas switch and the status of the pulse output switches. The rise time of the current is determined by the time difference between the first and last trigged laser triggering gas switches. In order to trigger the laser triggering gas switch, sufficient laser power is needed to be sent into the gap of the gas switches. The gas pressure and voltage difference on the two electrodes of the gas switches also affect the triggering of the gas switches, and the voltage added on the gas switch is determined by its transition time. Traditionally the trigger time difference should be less than the transition time of the two neighboring modules. A new simulation model of PTS shows one can break this transition time limits. Series of current pulse shaping experiments have been investigated on the PTS (Primary Test Stand. As results, more than 5 MA peak current were successfully achieved on the load with a rise time of 600 ns. This study and experiments of the pulse shaping on PTS demonstrate the adaptable ability of the PTS for offering different waveform of mega ampere current pulse for different research purpose.

  8. Study on Technology and Improved PTS Algorithm for PAPR Reduction in OFDM System%OFDM系统中降峰均比研究及PTS改进算法

    Institute of Scientific and Technical Information of China (English)

    何维武; 冯辉

    2011-01-01

    正交频分复用(OFDM)技术在解决无线移动通信系统中显示了许多特点,如抗多路径衰落和频际间的干扰等.然而,OFDM系统中一个最主要的瓶颈在于OFDM信号的峰均功率比(PAPR,Peak-to-Average Power Ratio)很大,因而容易导致OFDM信号的交调失真和系统性能的下降.如何有效地解决OFDM系统中的峰均功率比是亟待解决的问题.为此,提出一种新的PTS(部分传输序列)改进算法.

  9. Fidelity of Implementing an Assessment Translation and Adaptation Framework in a Study of an Emerging International Assessment

    Science.gov (United States)

    Chia, Magda Yanira

    2012-01-01

    This study addresses the complex process of translation and adaptation of two Collegiate Learning Assessment (CLA) performance tasks (PTs), originally developed in English for American students, into the languages and cultures of five participating countries. Focusing on confirming evidence bits (CEBs), disconfirming evidence bits (DEBs), and no…

  10. A Novel PTS of Streptococcus mutans is Responsible for Transport of Carbohydrates with α-1,3 linkage

    Science.gov (United States)

    Ajdic, Dragana; Chen, Zhiyun

    2012-01-01

    SUMMARY The most common type of carbohydrate-transport system in Streptococcus mutans is the phosphoenolpyruvate (PEP)-sugar phosphotransferase system (PTS). We previously showed that fourteen PTSs exist in S. mutans UA159 (Ajdic et al., 2002). Several studies have shown that microorganisms growing in biofilms express different genes as compared to their planktonic counterparts. In this study, we showed that one PTS of S. mutans was expressed in sucrose-grown biofilms. Furthermore, the same PTS was also responsible for the transport and metabolism of disaccharide nigerose (3-O-α-D-glucopyranosyl-D-glucose). Additionally, the results indicate that the studied PTS might be involved in the transport and metabolism of carbohydrates synthesized by glucosyltransferase B (GtfB) and glucosyltransferase C (GtfC) of S. mutans. To our knowledge, this is the first report that shows PTS transport of a disaccharide (and possibly extracellular oligosaccharides) with α-1,3 linkage. PMID:23193985

  11. Comparison of speed of anti-inflammatory and analgesic effect appearance of nimesulid and diclofenac sodium tablets in gout arthritis: a randomized study

    Directory of Open Access Journals (Sweden)

    F. M. Kudaeva

    2008-01-01

    Full Text Available To assess speed of anti-inflammatory and analgesic effect appearance of nimesulid and diclofenac sodium tablets in gout arthritis. 90 male pts with gout were included in an open clinical study. They were randomly assigned into three groups (30 pts in each. Group 1 pts received nimesulid tablets (Nise 100 mg twice a day, group 2 pts — tablets of an other nimesulid preparation and group 3 pts — diclofenac sodium 75 mg twice a day. Duration of treatment was 7 days. Nise significantly earlier provided anti-inflammatory and analgesic effect, gout arthritis, nimesulid, period till effect appearance, tolerability.

  12. Influence of combined therapy with prospidin and methotrexate on radiological progression, functional status and quality of life in pts with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    O. V. Simonova

    2004-01-01

    Full Text Available Objective. To evaluate influence of combination therapy with prospidin (P and methotrexate (MTX on X-ray progression, functional status (FS and quality of life (QL in patients with rheumatoid arthritis (RA in comparison with MTX monotherapy. Material and methods. 143 RA pts (129 female and 14 male were studied. Of them, there were. Mean age was 45.5±5.l years. Average duration of the disease was 4.5 years. 20 pts had II and 123 - 111 degree of RA activity. The second X-ray stage according to Steinbroker dominated. 72 pts of group I received P+MTX combination therapy. The therapy included intravenous drip-feed of P 200-300 mg per week in 200ml of 5% glucose and MTX 10 mg per week 1M. The maintaining therapy included P 100-200 mg per week IM and MTX 10 mg per week. 71 patients of group II received MTX monotherapy 10 mg per week. X-ray progression assessment was performed according to Sharp method. FS was evaluated with the HAQ questionnaire, Lee test. QL was evaluated with SF-36 scale. Pts were examined before and after I, 2, 3, 6 and 12 months of treatment. Results. There was no increase of X-ray progression of the disease in case of P+MTX therapy as compared with MTX monotherapy. Both methods resulted in improvement of FS parameters and physical health. Combination therapy significantly improved psychological health as well.

  13. Emerging Theoretical Models of Reading through Authentic Assessments among Preservice Teachers: Two Case Studies

    Science.gov (United States)

    Oboler, Eileen S.; Gupta, Abha

    2010-01-01

    This two-part study examines the emerging understanding of the reading process among preservice teachers (PTs), enrolled in a teacher preparation course on diagnostic reading. The study focuses on the use of reading assessment tools to understand the process of reading, while using reading inventories for diagnostic as well as pedagogical…

  14. Influence of radiation on endotoxin test using the PTS TM for 18-FDG radiopharmaceutical

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    Ralph Santos-Oliveira

    2010-09-01

    Full Text Available F-18 FDG (2-[18-F] fluoro-2-deoxy-D-glucose is the most frequently used radiopharmaceutical for PET and PET CT imaging exams. The FDA recently approved the use of the PTS TM (Portable Test System as an alternative to the standard test proposed by the United States Pharmacopeia using the LAL (Limulus Amebocyte Lysates, that takes longer to perform (about 1h than the PTS TM (15 min. Recent studies have demonstrated that radiation could interfere with the PTS TM test. In order to study the effects of radiation on the PTS TM test and/or equipment, 27 batches of F-18 FDG produced in the Nuclear Engineering Institute were analyzed. The results showed that no direct correlation with radiation was found in any of the cases.O FDG-18 é o radiofármaco mais utilizado nos exames de PET e PET CT. O FDA recentemente aprovou o uso do PTS TM (Portable Test System como método alternativo ao teste padrão de endotoxina, proposto pela Farmacopéia Americana, considerando que no primeiro há um tempo de espera de 1 hora frente a somente 15 minutos do segundo. Estudo recentes demonstram que a radiação poderia interferir no teste do PTS TM. De modo a avaliar os efeitos da radiação no teste PTS TM foram analisados 27 lotes de F-18 FDG produzidos no Instituto de Engenharia Nuclear. Os resultados demonstraram que em todos os casos nenhuma correlação direta com a radiação foi observada.

  15. Diagnostics for Z-pinch implosion experiments on PTS

    Energy Technology Data Exchange (ETDEWEB)

    Ren, X. D., E-mail: amosrxd@163.com; Huang, X. B., E-mail: amosrxd@163.com; Zhou, S. T., E-mail: amosrxd@163.com; Zhang, S. Q., E-mail: amosrxd@163.com; Dan, J. K., E-mail: amosrxd@163.com; Li, J., E-mail: amosrxd@163.com; Cai, H. C., E-mail: amosrxd@163.com; Wang, K. L., E-mail: amosrxd@163.com; Ouyang, K., E-mail: amosrxd@163.com; Xu, Q., E-mail: amosrxd@163.com; Duan, S. C., E-mail: amosrxd@163.com; Chen, G. H., E-mail: amosrxd@163.com; Wang, M., E-mail: amosrxd@163.com; Feng, S. P., E-mail: amosrxd@163.com; Yang, L. B., E-mail: amosrxd@163.com; Xie, W. P., E-mail: amosrxd@163.com; Deng, J. J., E-mail: amosrxd@163.com [Key Lab of Pulsed Power, Institute of Fluid Physics, CAEP, P.O. Box 919-108, Mianyang, Sichuan 621999 (China)

    2014-12-15

    The preliminary experiments of wire array implosion were performed on PTS, a 10 MA z-pinch driver with a 70 ns rise time. A set of diagnostics have been developed and fielded on PTS to study pinch physics and implosion dynamics of wire array. Radiated power measurement for soft x-rays was performed by multichannel filtered x-ray diode array, and flat spectral responses x-ray diode detector. Total x-ray yield was measured by a calibrated, unfiltered nickel bolometer which was also used to obtain pinch power. Multiple time-gated pinhole cameras were used to produce spatial-resolved images of x-ray self-emission from plasmas. Two time-integrated pinhole cameras were used respectively with 20-μm Be filter and with multilayer mirrors to record images produced by >1-keV and 277±5 eV self-emission. An optical streak camera was used to produce radial implosion trajectories, and an x-ray streak camera paired with a horizontal slit was used to record a continuous time-history of emission with one-dimensional spatial resolution. A frequency-doubled Nd:YAG laser (532 nm) was used to produce four frame laser shadowgraph images with 6 ns time interval. We will briefly describe each of these diagnostics and present some typical results from them.

  16. Construct validity of Croatian version of the Pavlovian Temperament Survey (PTS

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    Sanja Tatalović Vorkapić

    2012-10-01

    Full Text Available The aim of this study was to examine the construct validity of Pavlovian Temperament Survey (PTS by determining the relationship between three Strelau's dimensions of temperament (strength of excitation, strength of inhibition, mobility and basic dimensions of personality as were defined by Eysenck and in the five-factor model of personality. It was expected that strength of excitation and mobility would have significant positive correlations with extraversion and negative correlations with neuroticism, while strength of inhibition would show significant negative correlations with neuroticism. Within two studies (N1 = 74 female students, Mage = 22; N2 = 54 female students, Mage = 20, Croatian version of PTS, Five−Factor Nonverbal Personality Questionnaire FF−NPQ, and Eysenck's Personality Questionnaire EPQ R/A were used. The reliability coefficients for all three instruments were satisfactory, although not very high. Coefficients of correlation determined in the first study were not entirely in agreement with either theoretical expectations or empirical results of other authors, probably due to small sample size. However, the results of the second study were in accord with the expected pattern of significant correlations and that could be considered an indicator of good construct validity of PTS. Since this was a preliminary study the results provide only a general insight into the research aim, and represent a good starting point for future validation studies of the Croatian version of PTS.

  17. The methylotrophic yeast Hansenula polymorpha contains an inducible import pathway for peroxisomal matrix proteins with an N-terminal targeting signal (PTS2 proteins).

    Science.gov (United States)

    Faber, K N; Haima, P; Gietl, C; Harder, W; Ab, G; Veenhuis, M

    1994-12-20

    Two main types of peroxisomal targeting signals have been identified that reside either at the extreme C terminus (PTS1) or the N terminus (PTS2) of the protein. In the methylotrophic yeast Hansenula polymorpha the majority of peroxisomal matrix proteins are of the PTS1 type. Thus far, for H. polymorpha only amine oxidase (AMO) has been shown to contain a PTS2 type signal. In the present study we expressed H. polymorpha AMO under control of the strong endogenous alcohol oxidase promoter. Partial import of AMO into peroxisomes was observed in cells grown in methanol/(NH4)2SO4-containing medium. However, complete import of AMO occurred if the cells were grown under conditions that induce expression of the endogenous AMO gene. Similar results were obtained when the heterologous PTS2 proteins, glyoxysomal malate dehydrogenase from watermelon and thiolase from Saccharomyces cerevisiae, were synthesized in H. polymorpha. The import of PTS1 proteins, however, was not affected by the growth conditions. These results indicate that the reduced rate of AMO import in (NH4)2SO4-grown cells is not due to competition with PTS1 proteins for the same import pathway. Apparently, AMO is imported via a separate pathway that is induced by amines and functions for PTS2 proteins in general.

  18. TOPFLOW-PTS experiments. pre-test calculations with NEPTUNECFD code

    International Nuclear Information System (INIS)

    Hypothetical Small Break Loss Of Coolant Accident is identified as one of the most severe transients leading to a potential huge Pressurized Thermal Shock on the Reactor Pressure Vessel (RPV). This may result in two-phase flow configurations in the cold legs, according to the operating conditions, and to reliably assess the RPV wall integrity, advanced two-phase flow simulations are required. Related needs in development and/or validation of these advanced models are important, and the on-going TOPFLOW-PTS experimental program was designed to provide a well documented data base to meet these needs. This paper focuses on pre-test NEPTUNECFD simulations of TOPFLOW-PTS experiments; these simulations were performed to (i) help in the definition of the test matrix and test procedure, and (ii) check the presence of the different key physical phenomena at the mock-up scale. (author)

  19. Fluorescent co-localization of PTS1 and PTS2 and its application in analysis of the gene function and the peroxisomal dynamic in Magnaporthe oryzae

    Institute of Scientific and Technical Information of China (English)

    Jiao-yu WANG; Fu-cheng LIN; Guo-chang SUN; Xiao-yan WU; Zhen ZHANG; Xin-fa DU; Rong-yao CHAI; Xiao-hong LIU; Xue-qin MAO; Hai-ping QIU; Yan-li WANG

    2008-01-01

    The peroxisomal matrix proteins involved in many important biological metabolism pathways in eukaryotic cells are encoded by nucleal genes, synthesized in the cytoplasm and then transported into the organelles. Targeting and import of these proteins depend on their two peroxisomal targeting signals (PTS1 and PTS2) in sequence as we have known so far. The vectors of the fluorescent fusions with PTS, i.e., green fluorescence protein (GFP)-PTSI, GFP-PTS2 and red fluorescence protein (RFP)-PTS1, were constructed and introduced into Magnaporthe oryzae Guy11 cells. Transformants containing these fusions emitted fluorescence in a punctate pattern, and the locations of the red and green fluorescence overlapped exactly in RFP-PTS1 and GFP-PTS2 co-transformed strains. These data indicated that both PTS 1 and PTS2 fusions were imported into peroxisomes. A probable higher efficiency of PTSI machinery was revealed by comparing the fluorescence backgrounds in GFP-PTS1 and GFP-PTS2 transformants. By introducing both RFP-PTS1 and GFP-PTS2 into △mgpex6 mutants, the involvement of MGPEX6 gene in both PTS1 and PTS2 pathways was proved. In addition, using these transformants, the inducement of peroxisomes and the dynamic of peroxisomal number during the pre-penetration processes were investigated as well. In summary, by the localization and co-localization of PTSI and PTS2, we provided a useful tool to evaluate the biological roles of the peroxisomes and the related genes.

  20. Two-Phase Flow Simulations for PTS Investigation by Means of Neptune_CFD Code

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    Fabio Moretti

    2008-11-01

    Full Text Available Two-dimensional axisymmetric simulations of pressurized thermal shock (PTS phenomena through Neptune_CFD module are presented aiming at two-phase models validation against experimental data. Because of PTS complexity, only some thermal-hydraulic aspects were considered. Two different flow configurations were studied, occurring when emergency core cooling (ECC water is injected in an uncovered cold leg of a pressurized water reactor (PWR—a plunging water jet entering a free surface, and a stratified steam-water flow. Some standard and new implemented models were tested: modified turbulent k-ε models with turbulence production induced by interfacial friction, models for the drag coefficient, and interfacial heat transfer models. Quite good agreement with experimental data was achieved with best performing models for both test cases, even if a further improvement in phase change modelling would be suitable for nuclear technology applications.

  1. About molecular characteristic peripheral blood lymphocytes in pts with rheumatoid arthritis

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    I. R. Kolosova

    2003-01-01

    Full Text Available Objective. To study lymphocytes phenotype in rheumatoid arthritis (RA and its changes during methotrexate (MT therapy. Methods. 24 RA pts with high clinical and laboratory activity of the disease and 18 healthy donors (control group were included. All patients received MT 7,5-15 mg/week. They were followed up for 6 months. Expression of CD3, CD5, CD7, CD8, CD16, CD18, CD19, CD20, CD25, CD26, CD50, CD54, HLA DR, CD95 on peripheral blood lymphocytes was assessed before and after treatment by immunofluorescence method. Results. There was decreased expression of CD8, CD18, and CD50 in RA patients vs control. MT treatment resulted in reduction of CD 50 and CD 26 expression on lymphocytes. Conclusion. Peripheral blood in RA is characterized by decrease of CD8+ lymphocyte percent. Reduction of CD 18 and CD50 adhesion molecules expression may be connected with migration of appropriate effector cells bearing these molecules on there surface into inflamed synovial membrane. Treatment with MT decreased expression of some adhesion molecules. Decrease of CD 26 lymphocytes activation marker expression is one of the mechanisms of MT antirheumatic action.

  2. PTS Phosphorylation of Mga Modulates Regulon Expression and Virulence in the Group A Streptococcus

    OpenAIRE

    Hondorp, Elise R.; Hou, Sherry C.; Hause, Lara L.; Gera, Kanika; Lee, Ching-En; McIver, Kevin S.

    2013-01-01

    The ability of a bacterial pathogen to monitor available carbon sources in host tissues provides a clear fitness advantage. In the group A streptococcus (GAS), the virulence regulator Mga contains homology to phosphotransferase system (PTS) regulatory domains (PRDs) found in sugar operon regulators. Here we show that Mga was phosphorylated in vitro by the PTS components EI/HPr at conserved PRD histidines. A ∆ptsI (EI-deficient) GAS mutant exhibited decreased Mga activity. However, PTS-mediate...

  3. Molecular Recognition of PTS-1 Cargo Proteins by Pex5p: Implications for Protein Mistargeting in Primary Hyperoxaluria

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    Noel Mesa-Torres

    2015-02-01

    Full Text Available Peroxisomal biogenesis and function critically depends on the import of cytosolic proteins carrying a PTS1 sequence into this organelle upon interaction with the peroxin Pex5p. Recent structural studies have provided important insights into the molecular recognition of cargo proteins by Pex5p. Peroxisomal import is a key feature in the pathogenesis of primary hyperoxaluria type 1 (PH1, where alanine:glyoxylate aminotransferase (AGT undergoes mitochondrial mistargeting in about a third of patients. Here, we study the molecular recognition of PTS1 cargo proteins by Pex5p using oligopeptides and AGT variants bearing different natural PTS1 sequences, and employing an array of biophysical, computational and cell biology techniques. Changes in affinity for Pex5p (spanning over 3–4 orders of magnitude reflect different thermodynamic signatures, but overall bury similar amounts of molecular surface. Structure/energetic analyses provide information on the contribution of ancillary regions and the conformational changes induced in Pex5p and the PTS1 cargo upon complex formation. Pex5p stability in vitro is enhanced upon cargo binding according to their binding affinities. Moreover, we provide evidence that the rational modulation of the AGT: Pex5p binding affinity might be useful tools to investigate mistargeting and misfolding in PH1 by pulling the folding equilibria towards the native and peroxisomal import competent state.

  4. Substâncias tóxicas persistentes (STP no Brasil Persistent toxic substance (PTS in Brazil

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    Fernanda V. Almeida

    2007-01-01

    Full Text Available The present article presents an assessment of PTS in Brazil including polychlorinated biphenyls, polycyclic aromatic hydrocarbons, benzene hexachloride, aldrin, dieldrin, endrin, p,p,-DDT, p,p,DDE, p,p,-DDD, hexachlorocyclohexanes (alpha-HCH, beta-HCH, gamma-HCH and delta-HCH, endossulfan, heptachlor and pentachlorophenol. The data presented here are related to a survey of PTS levels in different environmental matrixes (soil, sediment, water, air, biota and human tissues (milk, blood, human hair, according to the scope of the UNEP-GEF Regionally Based Assessment of PTSs. Potential sources were evaluated considering national products and imports, since most of the literature does not allow source identification. Finally, Brazilian legislation was updated.

  5. The influence of finite-length flaw effects on PTS analyses

    International Nuclear Information System (INIS)

    Current licensing issues within the nuclear industry dictate a need to investigate the effects of cladding on the extension of small finite-length cracks near the inside surface of a vessel. Because flaws having depths of the order of the combined clad and heat affected zone thickness dominate the frequency distribution of flaws, their initiation probabilities can govern calculated vessel failure probabilities. Current pressurized-thermal-shock (PTS) analysis computer programs recognize the influence of the inner-surface cladding layer in the heat transfer and stress analysis models, but assume the cladding fracture toughness is the same as that for the base material. The programs do not recognize the influence cladding may have in inhibiting crack initiation and propagation of shallow finite-length surface flaws. Limited experimental data and analyses indicate the cladding can inhibit the propagation of certain shallow flaws. This paper describes an analytical study which was carried out to determine (1) the minimum flaw depth for crack initiation under PTS loading for semicircular surface flaws in a clad reactor pressure vessel and (2) the impact, in terms of the conditional probability of vessel failure, of using a semicircular surface flaw as the initial flaw and assuming that the flaw cannot propagate in the cladding. The analytical results indicate that for initiation a much deeper critical crack depth is required for the finite-length flaw than for the infinite-length flaw, except for the least severe transient. The minimum flaw depths required for crack initiation from the finite-length flaw analyses were incorporated into a modified version of the OCA-P code. The modified code was applied to the analysis of selected PTS transients, and the results produced a substantial decrease in the conditional probability of failure. This initial study indicates a significant effect on probabilistic fracture analyses by incorporating finite-length flaw results

  6. General overview of the TOPFLOW-PTS experimental program

    International Nuclear Information System (INIS)

    During a hypothetical loss-of-coolant accident, cold emergency core cooling water may be injected in a partially uncovered cold leg, and related two-phase CFD simulations are required to demonstrate the reactor pressure vessel integrity further to the resulting pressurized thermal shock. To complement the physical validation of the two-phase CFD codes in this configuration, a dedicated integral-type experimental program - TOPFLOW-PTS - has been setup; this paper (i) supports the validation data needs, (ii) presents the related experimental setup, and (iii) provides the general guidelines of the test matrix definition and test procedure. (author)

  7. PTS Infrasound portable array in Tunisia: Deployment and Results

    Science.gov (United States)

    Kallel, Mohamed; Khemiri, Lotfi; Mialle, Pierrick; Le Pichon, Alexis; Vergoz, Julien

    2014-05-01

    Within the scope of a scientific collaboration between the Tunisian NDC and the PTS an infrasound portable array (I66TN) were deployed in Tunisia for 6 Months starting from 15th of May 2013 till 15th of November 2013. The 4 sites of the portable array were installed in the mountain ranges surrounding the city of Aïn Draham in northwest of Tunisia with an aperture of about 1KM. The installation was done by Dr. Pierrick Mialle, a representative from the PTS, together with a team from the Tunisian NDC. Data retrieval is performed by the Tunisian NDC team on a periodic basis. The Data recorded by I66TN and the data recorded by the IMS Infrasound Station I48TN during the same period were processed. A bulletin of the fusion of the data of the two stations was created with the support of the French NDC. In this poster, we will present the different steps of the deployment of the station I66TN and show the results of the data processing and data fusion.

  8. Quality of life characteristics in assessment of diclofenac and Nise® efficacy in patients with gonarthritis

    Directory of Open Access Journals (Sweden)

    L V Sizova

    2003-01-01

    Full Text Available Objective. To study efficacy and safety of diclofenac and Nise® application in pts with gonarthritis. Material and methods. 60 pts with gonarthritis were included (mean age 53,4±9,5 years, mean disease duration 7,4±6,8 years. Quality of life was assessed with 4 questionnaires: Modified Stanford Health Assessment Questionnaire (MHAQ, SF-36, Nottingham Health Profile (NHP, Knee injury and Osteoarthritis Outcome Score (KOOS. 30 pts of group I received diclofenac 75 mg/day, 30 pis of group 11 were treated with Nise® 200 mg/day for 10 days. Multi-vitamins "Decamevitum" and injections of Xantinoli nicotinatis were used as additional treatment. Results. Diclofenac and Nise® showed good analgesic and anti-inflammatory effect. Both provided quality of life improvement in pts with gonarthrosis. Nise® was better tolerated.

  9. PAPR Reduction in OFDM Using Partial Transmit Sequence (PTS

    Directory of Open Access Journals (Sweden)

    R.Gayathri

    2013-04-01

    Full Text Available In recent years, OFDM has gained a lot of interest in diverse-digital communication applications. This has been due to its favorable properties like high spectral efficiency and robustness to channel fading. Some of the major drawbacks in OFDM are its high peak-to-average-power ratio(PAPR of the transmitted signals and the synchronization of signals. OFDM consist of large number of independent subcarriers, as a result of which the amplitude of such a signal can have high peak values. Coding, phase rotation and clipping are among many PAPR reduction schemes that have been proposed to overcome this problem. Significant reduction in PAPR has been achieved using Partial Transmit Sequence(PTS which comes under Signal scrambling techniques.

  10. Diversity of Streptococcus salivarius ptsH Mutants That Can Be Isolated in the Presence of 2-Deoxyglucose and Galactose and Characterization of Two Mutants Synthesizing Reduced Levels of HPr, a Phosphocarrier of the Phosphoenolpyruvate:Sugar Phosphotransferase System

    Science.gov (United States)

    Thomas, Suzanne; Brochu, Denis; Vadeboncoeur, Christian

    2001-01-01

    In streptococci, HPr, a phosphocarrier of the phosphoenolpyruvate:sugar phosphotransferase transport system (PTS), undergoes multiple posttranslational chemical modifications resulting in the formation of HPr(His∼P), HPr(Ser-P), and HPr(Ser-P)(His∼P), whose cellular concentrations vary with growth conditions. Distinct physiological functions are associated with specific forms of HPr. We do not know, however, the cellular thresholds below which these forms become unable to fulfill their functions and to what extent modifications in the cellular concentrations of the different forms of HPr modify cellular physiology. In this study, we present a glimpse of the diversity of Streptococcus salivarius ptsH mutants that can be isolated by positive selection on a solid medium containing 2-deoxyglucose and galactose and identify 13 amino acids that are essential for HPr to properly accomplish its physiological functions. We also report the characterization of two S. salivarius mutants that produced approximately two- and threefoldless HPr and enzyme I (EI) respectively. The data indicated that (i) a reduction in the synthesis of HPr due to a mutation in the Shine-Dalgarno sequence of ptsH reduced ptsI expression; (ii) a threefold reduction in EI and HPr cellular levels did not affect PTS transport capacity; (iii) a twofold reduction in HPr synthesis was sufficient to reduce the rate at which cells metabolized PTS sugars, increase generation times on PTS sugars and to a lesser extent on non-PTS sugars, and impede the exclusion of non-PTS sugars by PTS sugars; (iv) a threefold reduction in HPr synthesis caused a strong derepression of the genes coding for α-galactosidase, β-galactosidase, and galactokinase when the cells were grown at the expense of a PTS sugar but did not affect the synthesis of α-galactosidase when cells were grown at the expense of lactose, a noninducing non-PTS sugar; and (v) no correlation was found between the magnitude of enzyme derepression and

  11. Values of functional indexes in assessment of efficacy of osteoarthritis treatment with Chondrolon and Zel T in polyclinic

    Directory of Open Access Journals (Sweden)

    O Y Maiko

    2009-01-01

    Full Text Available Objective. To study change of knee joints functional disability in pts with predominantly I-II stage of knee osteoarthritis (OA with clinical tests and WOMAC index for assessment of efficacy of treatment with Chondrolon and Zel T in polyclinic. Material and methods. 70 pts with I and II stage of OA according to Kellgren-Lawrence aged from 40 to 67 years were included. They were divided in 2 groups (30 pts in group I and40 pts in group II. Group I pts were treated with Chondrolon and group II pts – with Zel T. Treatment efficacy was assessed with WOMAC index, functional Lequesne index, pain on VAS at rest and at movement, knee mobility, time of walking for 30 m and walking stairs. Results. Positive changes of all parameters were revealed in both groups: significant improvement of pain on VAS, functional tests, Lequesne index, WOMAC scales was achieved. During treatment with Zel T improvement of the efficacy measures increased slower, mainly after 12 weeks of treatment (during treatment with Chondrolon – after8 weeks. Both drugs provided functional improvement assessed by WOMAC index butChondrolon was more effective. Conclusion. Chondrolon and Zel T can be used for treatment of OA at I or II stage with moderate knee joints functional disability. Course of treatment with Zel T should be continued not less than 3 months and with Chondrolon – 2 months.

  12. The relevance of the non-canonical PTS1 of peroxisomal catalase

    NARCIS (Netherlands)

    Williams, Chris; Aksam, Eda Bener; Gunkel, Katja; Veenhuis, Marten; van der Klei, Ida J.

    2012-01-01

    Catalase is sorted to peroxisomes via a C-terminal peroxisomal targeting signal 1 (PTS1), which binds to the receptor protein Pex5. Analysis of the C-terminal sequences of peroxisomal catalases from various species indicated that catalase never contains the typical C-terminal PTS1 tripeptide-SKL, bu

  13. Evaluation of a portable test system for assessing endotoxin activity in raw milk.

    Science.gov (United States)

    Suzuki, Yohko; Suzuki, Kazuyuki; Shimamori, Toshio; Tsuchiya, Masakazu; Niehaus, Andrew; Lakritz, Jeffrey

    2016-01-01

    The aim of the present study was to compare endotoxin activities detected in raw milk samples obtained from cattle by a commercially available portable test system (PTS) and traditional microplate limulus amebocyte lysate (LAL)-based assay, which determined activities using a kinetic turbidimetric (KT) assay. Raw milk samples were obtained from 53 and 12 dairy cattle without and with clinical mastitis, respectively. Comparison between the KT and PTS was performed by the Friedman test. The Pearson product moment correlation coefficients were calculated to evaluate associations between any two continuous variables. Linear regression model analysis was also performed to obtain the equation describing the relationship between PTS and KT assay. The endotoxin activities detected in 200- or 400-fold diluted milk samples were similar between PTS and KT assay, whereas a significant difference was observed in 100-fold diluted milk (P<0.001). The results obtained from 200- (r(2)=0.778, P<0.001) and 400-fold diluted milk samples (r(2)=0.945, P<0.001) using PTS correlated with those using KT assay. The median milk endotoxin activities in Gram-positive and Gram-negative clinical mastitis cows were 0.655 and 11,523.5 EU/ml, respectively. The results of the present study suggest that PTS as a simple and easy test to assess endotoxin activity in raw milk is efficient, simple and reproducible. PMID:26279135

  14. Application of probabilistic fracture mechanics to the PTS issue

    International Nuclear Information System (INIS)

    As a part of the NRC effort to obtain a resolution to the PWR PTS issue, a probabilistic approach has been applied that includes a probabilistic fracture-mechanics (PFM) analysis. The PFM analysis is performed with OCA-P, a computer code that performs thermal, stress and fracture-mechanics analyses and estimates the conditional probability of vessel failure, P(F/E), using Monte Carlo techniques. The stress intensity factor (K/sub I/) is calculated for two- and three-dimensional surface flaws using superposition techniques and influence coefficients. Importance-sampling techniques are used, as necessary, to limit to a reasonable value the number of vessels actually calculated. Analyses of three PWR plants indicate that (1) the critical initial flaw depth is very small (5 to 15 mm), (2) the benefit of warm prestressing and the role of crack arrest are transient dependent, (3) crack arrest does not occur for the dominant transients, and (4) the single largest uncertainty in the overall probabilistic analysis is the number of surface flaws per vessel. 30 refs., 6 figs., 4 tabs

  15. PredPlantPTS1: A Web Server for the Prediction of Plant Peroxisomal Proteins.

    Science.gov (United States)

    Reumann, Sigrun; Buchwald, Daniela; Lingner, Thomas

    2012-01-01

    Prediction of subcellular protein localization is essential to correctly assign unknown proteins to cell organelle-specific protein networks and to ultimately determine protein function. For metazoa, several computational approaches have been developed in the past decade to predict peroxisomal proteins carrying the peroxisome targeting signal type 1 (PTS1). However, plant-specific PTS1 protein prediction methods have been lacking up to now, and pre-existing methods generally were incapable of correctly predicting low-abundance plant proteins possessing non-canonical PTS1 patterns. Recently, we presented a machine learning approach that is able to predict PTS1 proteins for higher plants (spermatophytes) with high accuracy and which can correctly identify unknown targeting patterns, i.e., novel PTS1 tripeptides and tripeptide residues. Here we describe the first plant-specific web server PredPlantPTS1 for the prediction of plant PTS1 proteins using the above-mentioned underlying models. The server allows the submission of protein sequences from diverse spermatophytes and also performs well for mosses and algae. The easy-to-use web interface provides detailed output in terms of (i) the peroxisomal targeting probability of the given sequence, (ii) information whether a particular non-canonical PTS1 tripeptide has already been experimentally verified, and (iii) the prediction scores for the single C-terminal 14 amino acid residues. The latter allows identification of predicted residues that inhibit peroxisome targeting and which can be optimized using site-directed mutagenesis to raise the peroxisome targeting efficiency. The prediction server will be instrumental in identifying low-abundance and stress-inducible peroxisomal proteins and defining the entire peroxisomal proteome of Arabidopsis and agronomically important crop plants. PredPlantPTS1 is freely accessible at ppp.gobics.de.

  16. PredPlantPTS1: a web server for the prediction of plant peroxisomal proteins

    Directory of Open Access Journals (Sweden)

    Sigrun eReumann

    2012-08-01

    Full Text Available Prediction of subcellular protein localization is essential to correctly assign unknown proteins to cell organelle-specific protein networks and to ultimately determine protein function. For metazoa, several computational approaches have been developed in the past decade to predict peroxisomal proteins carrying the peroxisome targeting signal type 1 (PTS1. However, plant-specific PTS1 protein prediction methods have been lacking up to now, and pre-existing methods generally were incapable of correctly predicting low-abundance plant proteins possessing non-canonical PTS1 patterns. Recently, we presented a machine learning approach that is able to predict PTS1 proteins for higher plants (spermatophytes with high accuracy and which can correctly identify unknown targeting patterns, i.e. novel PTS1 tripeptides and tripeptide residues. Here we describe the first plant-specific web server PredPlantPTS1 for the prediction of plant PTS1 proteins using the above-mentioned underlying models. The server allows the submission of protein sequences from diverse spermatophytes and also performs well for mosses and algae. The easy-to-use web interface provides detailed output in terms of (i the peroxisomal targeting probability of the given sequence, (ii information whether a particular non-canonical PTS1 tripeptide has already been experimentally verified, and (iii the prediction scores for the single C-terminal 14 amino acid residues. The latter allows identification of predicted residues that inhibit peroxisome targeting and which can be optimized using site-directed mutagenesis to raise the peroxisome targeting efficiency. The prediction server will be instrumental in identifying low-abundance and stress-inducible peroxisomal proteins and defining the entire peroxisomal proteome of Arabidopsis and agronomically important crop plants. PredPlantPTS1 is freely accessible at ppp.gobics.de.

  17. PAPR Reduction of OFDM Signals by Novel Global Harmony Search in PTS Scheme

    Directory of Open Access Journals (Sweden)

    Hojjat Salehinejad

    2012-01-01

    Full Text Available The orthogonal frequency division multiplexing (OFDM modulation technique is one of the key strategies for multiuser signal transmission especially in smart grids and wind farms. This paper introduces an approach for peak-to-average power ratio (PAPR reduction of such signals based on novel global harmony search (NGHS and partial transmit sequence (PTS schemes. In PTS technique, the data block to be transmitted is partitioned into disjoint subblocks, which are combined using phase factors to minimize PAPR. The PTS requires an exhaustive search over all combinations of allowed phase factors. Therefore, with respect to the fast implementation and simplicity of NGHS technique, we could achieve significant reduction of PAPR.

  18. Spine inflammatory changes in patients with ankylosing spondylitis assessed by magnetic resonance image

    Directory of Open Access Journals (Sweden)

    A G Bochkova

    2008-01-01

    Full Text Available Objective. To develop the optimal mode of spine evaluation with magnetic resonance image (MRl in pts with ankylosing spondylitis (AS and to study relationship between MR! signs of spinal inflammatory lesions (IL, spondylitis duration and clinical features of AS activity. Material and methods. MRl was performed in 36 pts (22 male, 14 female fulfilling the modified NY criteria of AS. Median age of pis was 26 years (range 19 - 55, Median AS duration - 8 years (range 1,8 - 24. 34 (97% pts were HLA-B27 positive. 21 (64% pts had high AS activity - median BASDAI 40 (range 10 - 77. 92% of pts had inflammatory spine pain (VAS>20 mm and 61% of pts had night pain. Median inflammatory pain duration had been defined separately for every part of the spine assessed by MRl. Median duration of axial pain was 36 months (range: 1-240. MR-scanning (Magnetom Symphony, Siemens, 1.5 T was performed inTl, T2 and T2-FS (fat signal suppression modes. IL scoring was done only in 29 pts evaluated in both sagittal and axial planes. We used two scoring methods: 1 individual IL score of the each spine element (vertebral bodies, processes, arches, zygapophyseai, costovertebral and costotransverse joints, ligaments, and 2 separate IL scoring in the vertebral bodies and posterior spinal elements in order "yes/no”. Results. 50 MRl images of different parts of the spine (8 cervical, 30 thoracic and 12 lumbar have been obtained in 36 pts. Spine IL were found in 35 pts. 26% of all IL were revealed in axial planes. 3 pts with short AS duration had IL only on axial slices (zygapophyseai lumbar joints, costotransverse joints, processes. IL were revealed more often in thoracic (average score: 7.1, than in lumbar (3.7 and cervical (2.1 spine. In most (26 from 29 pts, 90% pts IL were found in painful parts of spine. There was no IL score difference between pts(n=12 with low (BASDAI <40 and high (BASDAI>40; n=17 AS activity. Me and range were 4 (1.8-10.3 and 6 (4-16, respectively; p=0

  19. A Low-Complexity PTS Based on Greedy and Genetic Algorithm for OFDM Systems

    Institute of Scientific and Technical Information of China (English)

    LUO Renze; ZHANG Chengsen; NIU Na; LI Rui

    2015-01-01

    Partial transmit sequence (PTS) is one of eff ective technique to reduce high Peak-to-average power ratio (PAPR) in Orthogonal frequency division multiplex-ing (OFDM) system. However, the complexity of Original PTS (O-PTS) increases exponentially with the number of sub-blocks. To reduce the computational complexity while still off ering a lower PAPR, a new PTS method is pro-posed to search for suboptimal rotating vectors in this pa-per. In the proposed method, the candidate rotation vec-tors are generated based on greedy and genetic algorithm. We also combine the proposed method and the superim-posed training sequence method to get a further PAPR reduction. The theory and simulations results show that the proposed method can achieve better PAPR reduction and significantly reduce the computational complexity.

  20. PAPR Reduction in OFDM Systems Using PTS: With New Phase Sequences

    Directory of Open Access Journals (Sweden)

    Vrushali P. Phale

    2016-07-01

    Full Text Available Along with the advantages of OFDM signals like high spectral efficiency and robustness against ISI, main drawback of OFDM signals is high PAPR. Many techniques are proposed to reduce PAPR including amplitude clipping, clipping and filtering, coding, tone reservation (TR, tone injection (TI, active constellation extension (ACE, partial transmit sequence (PTS, selected mapping (SLM and interleaving. One of the effective methods, Partial Transmit Sequence is described in this article. In the conventional PTS (C-PTS several inverse fast Fourier transform (IFFT operations and complicated calculations to obtain optimum phase sequence, increase computational complexity of C-PTS. But in new proposed phase sequence the number of IFFT operations is reduced to half at the expense of a slight PAPR degradation. In this paper, a technique is proposed to reduce the number of IFFT operations to half at the expense of a slight PAPR degradation. Simulations are performed in Matlab with QPSK modulation with OFDM signal.

  1. PTS phosphorylation of Mga modulates regulon expression and virulence in the group A streptococcus.

    Science.gov (United States)

    Hondorp, Elise R; Hou, Sherry C; Hause, Lara L; Gera, Kanika; Lee, Ching-En; McIver, Kevin S

    2013-06-01

    The ability of a bacterial pathogen to monitor available carbon sources in host tissues provides a clear fitness advantage. In the group A streptococcus (GAS), the virulence regulator Mga contains homology to phosphotransferase system (PTS) regulatory domains (PRDs) found in sugar operon regulators. Here we show that Mga was phosphorylated in vitro by the PTS components EI/HPr at conserved PRD histidines. A ΔptsI (EI-deficient) GAS mutant exhibited decreased Mga activity. However, PTS-mediated phosphorylation inhibited Mga-dependent transcription of emm in vitro. Using alanine (unphosphorylated) and aspartate (phosphomimetic) mutations of PRD histidines, we establish that a doubly phosphorylated PRD1 phosphomimetic (D/DMga4) is completely inactive in vivo, shutting down expression of the Mga regulon. Although D/DMga4 is still able to bind DNA in vitro, homo-multimerization of Mga is disrupted and the protein is unable to activate transcription. PTS-mediated regulation of Mga activity appears to be important for pathogenesis, as bacteria expressing either non-phosphorylated (A/A) or phosphomimetic (D/D) PRD1 Mga mutants were attenuated in a model of GAS invasive skin disease. Thus, PTS-mediated phosphorylation of Mga may allow the bacteria to modulate virulence gene expression in response to carbohydrate status. Furthermore, PRD-containing virulence regulators (PCVRs) appear to be widespread in Gram-positive pathogens. PMID:23651410

  2. Non-canonical peroxisome targeting signals: identification of novel PTS1 tripeptides and characterization of enhancer elements by computational permutation analysis

    Directory of Open Access Journals (Sweden)

    Chowdhary Gopal

    2012-08-01

    Full Text Available Abstract Background High-accuracy prediction tools are essential in the post-genomic era to define organellar proteomes in their full complexity. We recently applied a discriminative machine learning approach to predict plant proteins carrying peroxisome targeting signals (PTS type 1 from genome sequences. For Arabidopsis thaliana 392 gene models were predicted to be peroxisome-targeted. The predictions were extensively tested in vivo, resulting in a high experimental verification rate of Arabidopsis proteins previously not known to be peroxisomal. Results In this study, we experimentally validated the predictions in greater depth by focusing on the most challenging Arabidopsis proteins with unknown non-canonical PTS1 tripeptides and prediction scores close to the threshold. By in vivo subcellular targeting analysis, three novel PTS1 tripeptides (QRL>, SQM>, and SDL> and two novel tripeptide residues (Q at position −3 and D at pos. -2 were identified. To understand why, among many Arabidopsis proteins carrying the same C-terminal tripeptides, these proteins were specifically predicted as peroxisomal, the residues upstream of the PTS1 tripeptide were computationally permuted and the changes in prediction scores were analyzed. The newly identified Arabidopsis proteins were found to contain four to five amino acid residues of high predicted targeting enhancing properties at position −4 to −12 in front of the non-canonical PTS1 tripeptide. The identity of the predicted targeting enhancing residues was unexpectedly diverse, comprising besides basic residues also proline, hydroxylated (Ser, Thr, hydrophobic (Ala, Val, and even acidic residues. Conclusions Our computational and experimental analyses demonstrate that the plant PTS1 tripeptide motif is more diverse than previously thought, including an increasing number of non-canonical sequences and allowed residues. Specific targeting enhancing elements can be predicted for particular sequences

  3. Two-phase CFD PTS validation in an extended range of thermohydraulics conditions covered by the COSI experiment

    International Nuclear Information System (INIS)

    Highlights: • Models for large interfaces in two-phase CFD were developed for PTS. • The COSI experiment is used for NEPTUNECFD integral validation. • COSI is a PWR cold leg scaled 1/100 for volume. • Fifty runs are calculated, covering a large range of flow configurations. • The CFD predicting capability is analysed using global and local measurements. - Abstract: In the context of the Pressurized Water Reactors (PWR) life duration safety studies, some models were developed to address the Pressurized Thermal Shock (PTS) from the two-phase CFD angle, dealing with interfaces much larger than cells size and with direct contact condensation. Such models were implemented in NEPTUNECFD, a 3D transient Eulerian two-fluid model. The COSI experiment is used for its integral validation. It represents a cold leg scaled 1/100 for volume and power from a 900 MW PWR under a large range of LOCA PTS conditions. In this study, the CFD is evaluated in the whole range of parameters and flow configurations covered by the experiment. In a first step, a single choice of mesh and CFD models parameters is fixed and justified. In a second step, fifty runs are calculated. The CFD predicting capability is analysed, comparing the liquid temperature and the total condensation rate with the experiment, discussing their dependency on the inlet cold liquid rate, on the liquid level in the cold leg and on the difference between co-current and counter-current runs. It is shown that NEPTUNECFD 1.0.8 calculates with a fair agreement a large range of flow configurations related to ECCS injection and steam condensation

  4. The Performance Analysis of PAPR Reduction using a novel PTS technique in OFDM-MIMO System

    Directory of Open Access Journals (Sweden)

    Kashish Sareen

    2012-08-01

    Full Text Available Orthogonal Frequency Division Multiplexing (OFDM is an new multiplexing technique for 4G and 4.5G generation wireless communication. MIMO-OFDM is latest multiplexing technique which is resposible for high performance 4G broadband wireless communications. But there is one main disadvantage of MIMO-OFDM is the high peak-to-average power ratio (PAPR of the transmitter’s output signal on different antennas. In this paper, we present a new noble (PTS Partial transmit sequence technique to reduce PAPR problem in OFDM-MIMO system. This new PTS technique gives us better PAPR Reduction gain in OFDM-MIMO as compared with original and another PTS Techniques.

  5. PAPR Reduction Using BPSO/PTS and STBC in MIMO OFDM System

    Directory of Open Access Journals (Sweden)

    Karima El Mouhib

    2011-01-01

    Full Text Available Problem statement: The Multiple Input Multiple Output (MIMO Orthogonal Frequency Division Multiplexing (OFDM system has been receiving a great attention, as one of solutions for achieving high speed, efficient and high-quality service for the wireless communications. However, the transmitted signal still has high PAPR because of OFDM characteristics. Many methods have been proposed to solve this problem, but the most of them decrease high Peak-to-Average Power Ratio (PAPR as well as the data rate. Approach: This proposal described a new suboptimal technique for reduction of the PAPR by combining two suitable methods for MIMO OFDM systems. The first method was based on Boolean Particle Swarm intelligence Optimization (BPSO applied to Partial transmit Sequence (PTS and the second was the Space Time Bloc Coding (STBC. Result: Apply only the PTS technique and independently on each transmitted antenna, was effective to reduce PAPR, but it requires high computation complexity. Therefore, the BPSO/PTS technique provided better performance and it was been promoted as an uncomplicated way for PAPR reduction. Thanks of the BPSO/PTS algorithm; the transmitted sequence was selected with minimizing the maximum PAPR over all transmission antennas. The simulations and the BER performance demonstrated that more inertia weight and phase weighting factor obtained better PAPR reduction performance without bringing much higher complexity. Conclusion: Results show that the added BPSO/PTS method to orthogonal space time bloc coding minimizes computational complexity cost as well as the PAPR and gives best optimal PTS performance in comparison with the conventional methods.

  6. PTS-TR方法降低CO-OFDM系统的PAPR%PTS-TR Method For PAPR Reduction In Coherent Optical OFDM Systems

    Institute of Scientific and Technical Information of China (English)

    司亚楠; 陈鹏

    2012-01-01

    In coherent optical OFDM system, the signal having a larger PAPR wall produce a serious distortion, and greatly reduce the efficiency of the system. In order to contain the PAPR in coherent optical OFDM system, a new method of PTS-TR is presented. The simulation results show that compared with the traditional TR or PTS method,the effect of the new method has greater stability and smaller computational complexity, it has a better performance of PAPR reduction, and is more suitable for coherent optical OFDM system.%在相干光正交频分复用(CO-OFDM)系统中,较高的峰均功率比会使信号产生严重的畸变,导致系统误码率性能的严重下降,为了抑制CO-OFDM系统的PAPR提出了一种PTS-TR方法.仿真结果表明,该方法与传统TR方法和PTS方法相比,具有很高的稳定性和更小的运算复杂度,对PAPR的抑制性能较好,更适用于CO-OFDM系统.

  7. Validation of the Large Interface Method of NEPTUNE{sub C}FD 1.0.8 for Pressurized Thermal Shock (PTS) applications

    Energy Technology Data Exchange (ETDEWEB)

    Coste, P., E-mail: pierre.coste@cea.fr [CEA, DEN, DER/SSTH, F-38054 Grenoble (France); Lavieville, J. [Electricite de France, Chatou (France); Pouvreau, J. [CEA, DEN, DER/SSTH, F-38054 Grenoble (France); Baudry, C.; Guingo, M.; Douce, A. [Electricite de France, Chatou (France)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer The two-phase Pressurized Thermal Shock (PTS) is a key thermohydraulics issue for PWR safety. Black-Right-Pointing-Pointer The dynamic and condensation models are firstly validated separately. Black-Right-Pointing-Pointer Then the global validation is done with the COSI experiment. Black-Right-Pointing-Pointer All the calculations performed with the same set of models both in the Large Interface Method and in the k-{epsilon} approach for turbulence substantiate the application of the tool to PTS. - Abstract: NEPTUNE{sub C}FD is a code based on a 3D transient Eulerian two-fluid model. One of the main application targets is the two-phase Pressurized Thermal Shock (PTS), which is related to PWR Reactor Pressure Vessel (RPV) lifetime safety studies, when sub-cooled water from Emergency Core Cooling (ECC) system is injected into the possibly uncovered cold leg and penetrates into the RPV downcomer. Five experiments were selected for the validation, a selection reviewed by a panel of European experts. The dynamic models are validated with a co-current smooth and wavy air-water stratified flow in a rectangular channel with detailed measurements of turbulence and velocities. The condensation models are validated with a co-current smooth and wavy steam-water stratified flow in a rectangular channel with measurements of the steam flow rates. The dynamic models are validated in the situation of a jet impinging a pool free surface with two experiments dealing with a water jet impingement on a water pool free surface in air environment. Finally, all the models involved in the reactor conditions are validated with the COSI experiment. The calculations are done with the same set of Large Interface Method models and a RANS (k-{epsilon}) approach for turbulence. They substantiate the application of the tool to PTS studies.

  8. Service framework for Internet of People, Things and Services (IoPTS)

    DEFF Research Database (Denmark)

    Shinde, Gitanjali; Olesen, Henning

    2016-01-01

    the literature work,a detaileddiscussionon the requirements, functionalities and need of the user-centric service frameworkthat is needed to realize IoPTS is presented in this work.We propose amodified Bluetooth Low Energy (BLE) beacon to advertise the services present at a particular location in the view...

  9. Construction of Listeria monocytogenes mutants with in-frame deletions in the phosphotransferase transport system (PTS) and analysis of their growth under stress conditions.

    Science.gov (United States)

    Liu, Yanhong; Ceruso, Marina; Jiang, Yuji; Datta, Atin R; Carter, Laurenda; Strain, Errol; Pepe, Tiziana; Anastasi, Aniello; Fratamico, Pina

    2013-09-01

    Listeria monocytogenes is a foodborne pathogen that is difficult to eliminate due to its ability to survive under different stress conditions such as low pH and high salt. To better control this pathogen in food, it is important to understand its survival mechanisms under these stress conditions. LMOf2365_0442, 0443, and 0444 encode for phosphotransferase transport system (PTS) permease (fructose-specific IIABC components) that is responsible for sugar transport. LMOf2365_0445 encodes for glycosyl hydrolase. These genes were induced by high pressure and inhibited under salt treatments; therefore, we hypothesized that genes encoding these PTS proteins may be involved in general stress responses. To study the function of these genes, deletion mutants of the PTS genes (LMOf2365_0442, LMOf2365_0443, and LMOf2365_0444) and the downstream gene LMOf2365_0445 were created in L. monocytogenes strain F2365. These deletion mutants were tested under different stress conditions. The growth of ∆LMOf2365_0445 was increased under nisin (125 μg/mL) treatments compared to the wild-type (P salt (brain-heart infusion medium with 5% NaCl) was significantly increased (P monocytogenes. An understanding of the growth of these mutants under multiple stress conditions may assist in the development of intervention strategies to control L. monocytogenes in food. PMID:23909479

  10. A ptsP deficiency in PGPR Pseudomonas fluorescens SF39a affects bacteriocin production and bacterial fitness in the wheat rhizosphere.

    Science.gov (United States)

    Godino, Agustina; Príncipe, Analía; Fischer, Sonia

    2016-04-01

    Pseudomonas fluorescens SF39a is a plant-growth-promoting bacterium isolated from wheat rhizosphere. In this report, we demonstrate that this native strain secretes bacteriocins that inhibit growth of phytopathogenic strains of the genera Pseudomonas and Xanthomonas. An S-type pyocin gene was detected in the genome of strain SF39a and named pys. A non-polar pys::Km mutant was constructed. The bacteriocin production was impaired in this mutant. To identify genes involved in bacteriocin regulation, random transposon mutagenesis was carried out. A miniTn5Km1 mutant, called P. fluorescens SF39a-451, showed strongly reduced bacteriocin production. This phenotype was caused by inactivation of the ptsP gene which encodes a phosphoenolpyruvate phosphotransferase (EI(Ntr)) of the nitrogen-related phosphotransferase system (PTS(Ntr)). In addition, this mutant showed a decrease in biofilm formation and protease production, and an increase in surface motility and pyoverdine production compared with the wild-type strain. Moreover, we investigated the ability of strain SF39a-451 to colonize the wheat rhizosphere under greenhouse conditions. Interestingly, the mutant was less competitive than the wild-type strain in the rhizosphere. To our knowledge, this study provides the first evidence of both the relevance of the ptsP gene in bacteriocin production and functional characterization of a pyocin S in P. fluorescens. PMID:26708985

  11. The methylotrophic yeast Hansenula polymorpha contains an inducible import pathway for peroxisomal matrix proteins with an N-terminal targeting signal (PTS2 proteins)

    NARCIS (Netherlands)

    Faber, Klaas Nico; Haima, Pieter; Gietl, Christine; Harder, Willem; Ab, Geert; Veenhuis, Marten

    1994-01-01

    Two main types of peroxisomal targeting signals have been identified that reside either at the extreme C terminus (PTS1) or the N terminus (PTS2) of the protein. In the methylotrophic yeast Hansenula polymorpha the majority of peroxisomal matrix proteins are of the PTS1 type. Thus far, for H. polymo

  12. Synbiotic impact of tagatose on viability of Lactobacillus rhamnosus strain GG mediated by the phosphotransferase system (PTS).

    Science.gov (United States)

    Koh, Ji Hoon; Choi, Seung Hye; Park, Seung Won; Choi, Nag-Jin; Kim, Younghoon; Kim, Sae Hun

    2013-10-01

    Synbiotics, the combination of prebiotics and probiotics, has been shown to produce synergistic effects that promote gastrointestinal well-being of host. Tagatose is a low calorie food ingredient with putative health-promoting benefits. Herein, we investigated its synbiotic impact on the viability of Lactobacillus casei 01 and Lactobacillus rhamnosus strain GG and the potential mechanism involved. Tagatose, as a synbiotic substrate, enhanced the growth of L. casei 01 and L. rhamnosus strain GG compared to other prebiotics. Other gut-indigenous such as Clostridium spp. readily utilized fructooligosaccharide (FOS), the most widely used functional prebiotics, but not tagatose. Additionally, tagatose enhanced probiotic functions of L. casei 01 and L. rhamnosus strain GG by reinforcing their attachment on HT-29 intestine epithelial cells and enhancing their cholesterol-lowering activities. Whole transcriptome study and quantitative real-time polymerase chain reaction (qRT-PCR) test showed that the presence of tagatose in L. rhamnosus strain GG caused induction of a large number of genes associated with carbohydrate metabolism including the phosphotransferase system (PTS). Collectively, these results indicate the tagatose enhanced the growth of L. casei 01 and L. rhamnosus strain GG and their probiotic activities by activating tagatose-associated PTS networks. Importantly, this study highlights the potential application of tagatose and L. casei 01 and/or L. rhamnosus strain GG as a synbiotic partner in functional dairy foods (i.e. yogurt and cheese) and therapeutic dietary supplements.

  13. Synbiotic impact of tagatose on viability of Lactobacillus rhamnosus strain GG mediated by the phosphotransferase system (PTS).

    Science.gov (United States)

    Koh, Ji Hoon; Choi, Seung Hye; Park, Seung Won; Choi, Nag-Jin; Kim, Younghoon; Kim, Sae Hun

    2013-10-01

    Synbiotics, the combination of prebiotics and probiotics, has been shown to produce synergistic effects that promote gastrointestinal well-being of host. Tagatose is a low calorie food ingredient with putative health-promoting benefits. Herein, we investigated its synbiotic impact on the viability of Lactobacillus casei 01 and Lactobacillus rhamnosus strain GG and the potential mechanism involved. Tagatose, as a synbiotic substrate, enhanced the growth of L. casei 01 and L. rhamnosus strain GG compared to other prebiotics. Other gut-indigenous such as Clostridium spp. readily utilized fructooligosaccharide (FOS), the most widely used functional prebiotics, but not tagatose. Additionally, tagatose enhanced probiotic functions of L. casei 01 and L. rhamnosus strain GG by reinforcing their attachment on HT-29 intestine epithelial cells and enhancing their cholesterol-lowering activities. Whole transcriptome study and quantitative real-time polymerase chain reaction (qRT-PCR) test showed that the presence of tagatose in L. rhamnosus strain GG caused induction of a large number of genes associated with carbohydrate metabolism including the phosphotransferase system (PTS). Collectively, these results indicate the tagatose enhanced the growth of L. casei 01 and L. rhamnosus strain GG and their probiotic activities by activating tagatose-associated PTS networks. Importantly, this study highlights the potential application of tagatose and L. casei 01 and/or L. rhamnosus strain GG as a synbiotic partner in functional dairy foods (i.e. yogurt and cheese) and therapeutic dietary supplements. PMID:23764214

  14. Numerical simulations of the TOPFLOW-PTS steam-water experiment

    International Nuclear Information System (INIS)

    The correct analysis of the Pressurized Thermal Shock requires the simulation of the thermal mixing that occurs when cold Emergency Core Cooling (ECC) water is injected into the cold leg, where it flows to the downcomer and mixes with the hot coolant present in the primary circuit. In the framework of the NURISP (NUclear Reactor Integrated Simulation Project) project attempts are being made to improve the CFD modeling for two-phase PTS scenarios. For this purpose, two steady-state reference cases from the TOPFLOW-PTS experimental program were defined: one for air-water and one for steam-water flow. The current paper focuses only on the steam-water reference case. The pre-test simulations were performed with the commercial CFD code ANSYS CFX 12.0. The simulations of the steam-water reference test predicted a thermal stratification in the cold leg at the entrance into the downcomer and in the downcomer itself. (author)

  15. Low-Complexity SLM and PTS Schemes for PAPR Reduction in OFDM Systems

    Science.gov (United States)

    Wang, Chin-Liang; Ouyang, Yuan; Hsu, Ming-Yen

    One major drawback of orthogonal frequency-division multiplexing is the high peak-to-average power ratio (PAPR) of the output signal. The selected mapping (SLM) and partial transmit sequences (PTS) methods are two promising techniques for PAPR reduction. However, to generate a set of candidate signals, these techniques need a bank of inverse fast Fourier transforms (IFFT's) and thus require high computational complexity. In this paper, we propose two low-complexity multiplication-free conversion processes to replace the IFFT's in the SLM method, where each conversion process for an N-point IFFT involves only 3N complex additions. Using these proposed conversions, we develop several new SLM schemes and a combined SLM & PTS method, in which at least half of the IFFT blocks are reduced. Computer simulation results show that, compared to the conventional methods, these new schemes have approximately the same PAPR reduction performance under the same number of candidate signals for transmission selection.

  16. Accumulation of chlorinated and brominated persistent toxic substances (PTS) and their relationship to testosterone suppression in Norway rats from Japan

    Energy Technology Data Exchange (ETDEWEB)

    Takasuga, T.; Senthilkumar, K. [Shimadzu Techno-Research Inc. (Japan); Ishizuka, M.; Fujita, S. [Graduate School of Veterinary Medicine, Hokkaido Univ. (Japan); Tanikawa, R. [Inst. of Tech., Ikari Corp. (Japan)

    2004-09-15

    Contamination of chlorinated/brominated persistent toxic substances (PTS) such as polychlorinated, -dibenzo-p-dioxins (PCDDs), -dibenzofurans (PCDFs), -biphenyls (PCBs), - organochlorine pesticides (OCPs) {l_brace}e.g., aldrin, dieldrin, endrin, chlordane compounds [cis/transchlordane, cis/trans-nonachlor, oxychlordane, heptachlor, heptachlor epoxide], hexachlorobenzene (HCB), 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDTs) and its metabolities [o,p/p,p'-DDD and DDE] and hexachlorocyclohexane (HCHs){r_brace} and -brominated diphenyl ethers (PBDEs) are considered to important class of chemicals due to persistence in nature, bioaccumulation potential and adverse health effects in wildlife and humans. Among South East Asian countries, Japan reported to contaminated with aforesaid chemicals with considerable amounts. There is no document reports contamination of PTS in wild animals, which in-habit near humans. Norway rat (NR) inhabits not only near human environment but also distributed worldwide. Especially, NR feeds on human waste and shelter in and around human environment and thus exposure of toxic contaminants in this animal considered to similar with those in humans. In addition, rats have unique physiology that match with humans (e.g., they have similar pathogens as humans have). Therefore, analysis of toxic contaminants in NR considered as indirect measure in humans. Considering those facts, in this study, we analyzed NR collected from urban area, rural area, waste dumping or land fill site and isolated remote island from Japan. Particularly several chlorinated and brominated organic contaminants such as PCDDs, PCDFs, PCBs, DDTs, HCHs, chlordane compounds, heptachlor, heptachlor epoxide, HCB, aldrin, dieldrin, endrin and PBDEs were analyzed in rat livers by isotope dilution technique using HRGC-HRMS. In addition, laboratory Wistar rats (WR) were used as control.

  17. Remodeling and Characterization of Pneumatic Transfer System (PTS no.3) of HANARO Research Reactor for Neutron Activation Analysis

    International Nuclear Information System (INIS)

    A pneumatic transfer system (PTS) is one of the facilities to be used in an irradiation of a target material for an instrumental neutron activation analysis (INAA) in a research reactor. This technical report describes for the irradiation test and the characteristics and removing, remodelling of the reinstalled PTS no.3 in NAA no.3 irradiation hole at HANARO for user information and the reactor management

  18. TOPFLOW-PTS air-water experiments on the phase separation in the ECC nozzle and the ECC water mixing during PTS scenarios

    International Nuclear Information System (INIS)

    In two-phase Pressurized Thermal Shock scenarios several thermal hydraulic phenomena, such as direct contact condensation, entrainment of steam bubbles and multi-scale momentum transfer are involved. The TOPFLOW-PTS experimental assembly represents a 1:2.5 scaled model of a PWR downcomer, cold leg with emergency core cooling injection and a pump simulator. It is build up for the development and validation of CFD models. The setup is highly instrumented - a large number of thermocouples, an infrared and a high-speed camera as well as wire mesh sensors are used to obtain CFD-grade data. As a first step air-water experiments were done with the special aim to investigate the behaviour of the liquid jet from the ECC injection into the cold leg. They indicated that the jet momentum at the impact position is very important for the mixing process and stratification inside the ECC nozzle needs to be considered in CFD calculations. (author)

  19. Audit and Assessment Studies

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Craig [Tlingit-Haida Regional Housing Authority, Juneau, AK (United States)

    2016-03-22

    Project to assess 46 low-income multifamily residences owned and managed by THRHA in up to 14 southeast Alaska communities. The Objective of project was to identify efficiency measures to reduce energy costs by 30% for low-income multifamily housing by; 1. Decreasing energy demand by increasing multifamily housing energy efficiency; 2. Reducing household energy consumption through energy conservation education and installation of energy upgrades; and 3. Projecting energy savings based on fossil fuel reduction to environmentally and economically benefit Tribal southeast communities

  20. Effect of the dilution factor on {sup 18}FDG and Na{sup 18}F samples for bacterial endotoxin test using PTS (portable test system)

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, Marina B.; Costa, Flavia M.; Ferreira, Soraya Z., E-mail: mbs@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Unidade de Pesquisa e Producao de Radiofarmacos

    2011-07-01

    {sup 18}FDG and Na{sup 18}F are radiopharmaceuticals produced as sterile solutions suitable for intravenous administration, which must contain no more than 175 EV/V. The most commonly used approach to detect endotoxins is the gelclot technique that requires 60 minutes for results. For radiopharmaceuticals containing short-life radionuclides, such as {sup 18}F, there is an increasing interest for faster quality control methods. FDA licensed the Endosafe, PTS, a kinetic chromogenic endotoxin detection system that takes about 15 minutes for results. As other techniques, PTS test is susceptible to interferences which can be solved by product dilution. The aim of this study was to establish the best dilution of {sup 18}FDG and Na{sup 18}F for PTS analysis. Two different dilution factors for {sup 18}FDG and 1:10 for Na{sup 18}F were essayed: 1:10 and 1:100. {sup 18}FDG and Na{sup 18} solutions were prepared by the addition of LAL reagent water. Considering the assay acceptance criteria, the best dilution factor was 1:100 for {sup 18}FDG and 1:10 for Na{sup 18}F. The recovery of the product positive control was 98-12% for {sup 18}FDG 1:100 and 104-120% for Na{sup 18}F 1:10, which were, in both cases, within the specification (50-200%) and very close to 100%. Results obtained with these dilution studies were important to establish the most appropriate and non-interfering dilution factor for {sup 18}FDG and Na{sup 18}F routine endotoxin test. (author)

  1. Effect of the dilution factor on 18FDG and Na18F samples for bacterial endotoxin test using PTS (portable test system)

    International Nuclear Information System (INIS)

    18FDG and Na18F are radiopharmaceuticals produced as sterile solutions suitable for intravenous administration, which must contain no more than 175 EV/V. The most commonly used approach to detect endotoxins is the gelclot technique that requires 60 minutes for results. For radiopharmaceuticals containing short-life radionuclides, such as 18F, there is an increasing interest for faster quality control methods. FDA licensed the Endosafe, PTS, a kinetic chromogenic endotoxin detection system that takes about 15 minutes for results. As other techniques, PTS test is susceptible to interferences which can be solved by product dilution. The aim of this study was to establish the best dilution of 18FDG and Na18F for PTS analysis. Two different dilution factors for 18FDG and 1:10 for Na18F were essayed: 1:10 and 1:100. 18FDG and Na18 solutions were prepared by the addition of LAL reagent water. Considering the assay acceptance criteria, the best dilution factor was 1:100 for 18FDG and 1:10 for Na18F. The recovery of the product positive control was 98-12% for 18FDG 1:100 and 104-120% for Na18F 1:10, which were, in both cases, within the specification (50-200%) and very close to 100%. Results obtained with these dilution studies were important to establish the most appropriate and non-interfering dilution factor for 18FDG and Na18F routine endotoxin test. (author)

  2. The Performance Analysis of PAPR Reduction using a novel PTS technique in OFDM-MIMO System

    OpenAIRE

    Kashish Sareen

    2012-01-01

    Orthogonal Frequency Division Multiplexing (OFDM) is an new multiplexing technique for 4G and 4.5G generation wireless communication. MIMO-OFDM is latest multiplexing technique which is resposible for high performance 4G broadband wireless communications. But there is one main disadvantage of MIMO-OFDM is the high peak-to-average power ratio (PAPR) of the transmitter’s output signal on different antennas. In this paper, we present a new noble (PTS) Partial transmit sequence technique to reduc...

  3. Patient’s satisfaction after 2-piece inflatable penile prosthesis implantation: An Italian multicentric study

    Directory of Open Access Journals (Sweden)

    Giorgio Gentile

    2016-03-01

    Full Text Available Introduction: Penile prosthesis implant represents a valuable solution for pts with severe erectile dysfunction (ED, non-responders to medical management. The aim of our study was to evaluate the satisfaction of patients (pts after 2-pieces inflatable penile prosthesis (IPP. Aim of the study: to evaluate safety, reliability and post-operative patient’s satisfaction after implantation of two-pieces IPP. Materials and Methods: This retrospective multicentric analysis concerns a group of 42 patients undergone 2-pieces IPP implantation from November 2005 to November 2013, in four Centers of proven experience. As a first step, a detailed review of all clinical reports was performed. Secondly, every patient was asked to fill the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS specifically modified, in order to assess their own satisfaction after surgery and, its impact on patient’s quality of sexual life. Results: 42 pts were evaluated (AMS-Ambicor: 28; Coloplast- Excell: 14; mean age, at time of operation: 60,7 years; mean follow up: 27,6 months; etiology of ED: vascular 23,8%, diabetes 19%, La Peyronie D. 7,1%, consequence of radical prostatectomy 31%, consequence of other pelvic surgery 11,9%, spinal trauma 7%. Mean operative time: 117 ± 58 min, mean postoperative hospital stay 3 ± 1,6 days. Post operative short-term complications: 4 pts (9,5%. Post operative long-term complications: 4 pts (9,5%. Long-term functional results (Questionnaire: 71% of pts (30 reported regular use of the prosthesis, at least 1 time/week, the satisfaction was good in 42% of pts (18, quite good in 33,3% (14, quite bad in 2,4% (1, very bad in 7,1% (3, 6 pts (14,4% didn’t answer. Conclusions: 2 pieces IPP appears to be associated with a low complication rate and good satisfaction of pts especially in the elderly. It also assures satisfactory rates of aesthetics and functional results.

  4. Modified PTS with FECs for PAPR Reduction in MIMO-OFDM System with Different Subblocks and Subcarriers

    Directory of Open Access Journals (Sweden)

    Mukunthan Pandurangan

    2011-07-01

    Full Text Available Multiple input multiple output orthogonal frequency division multiplexing (MIMO-OFDM systems have been proposed in the recent past for providing high data-rate services over wireless channels. When combined with space time coding it provides the advantages of space-time coding and OFDM, resulting in a spectrally efficient wideband communication system. However, MIMO OFDM systems suffer with the problem of inherent high peak-to-average power ratio (PAPR due to the intersymbol interference between the subcarriers. In order to obtain optimal PAPR reduction using the partial transmitted sequence (PTS, the total search for the number of subblocks and the rotation factors must be accomplished. As the number of subblocks and rotation factors increases, PAPR reduction improves. The number of calculation increases as the number of subblocks increases, such that complexity increases exponentially and the process delay occurs simultaneously. In this paper, a generalised framework for PAPR reduction for MIMO OFDM systems based on modified PTS using forward error-correcting codes (FECs such as Turbo codes and Golay codes are employed. PAPR reduction is jointly optimised in both the real and imaginary part by use of fast Fourier transform (FFT algorithm in the modified PTS which can be utilized for finding the optimum phase weighting factors, and can achieve the lower PAPR and computational complexity of MIMO OFDM systems. The simulation results show that the combined FEC with modified PTS technique significantly provides better PAPR reduction with reduced computational complexity compared to original PTS technique in the MIMOOFDM systems.

  5. Variable length adjacent partitioning for PTS based PAPR reduction of OFDM signal

    Energy Technology Data Exchange (ETDEWEB)

    Ibraheem, Zeyid T.; Rahman, Md. Mijanur; Yaakob, S. N.; Razalli, Mohammad Shahrazel; Kadhim, Rasim A. [School of Computer and Communication Engineering, Universiti Malaysia Perlis, 02600 Arau, Perlis (Malaysia)

    2015-05-15

    Peak-to-Average power ratio (PAPR) is a major drawback in OFDM communication. It leads the power amplifier into nonlinear region operation resulting into loss of data integrity. As such, there is a strong motivation to find techniques to reduce PAPR. Partial Transmit Sequence (PTS) is an attractive scheme for this purpose. Judicious partitioning the OFDM data frame into disjoint subsets is a pivotal component of any PTS scheme. Out of the existing partitioning techniques, adjacent partitioning is characterized by an attractive trade-off between cost and performance. With an aim of determining effects of length variability of adjacent partitions, we performed an investigation into the performances of a variable length adjacent partitioning (VL-AP) and fixed length adjacent partitioning in comparison with other partitioning schemes such as pseudorandom partitioning. Simulation results with different modulation and partitioning scenarios showed that fixed length adjacent partition had better performance compared to variable length adjacent partitioning. As expected, simulation results showed a slightly better performance of pseudorandom partitioning technique compared to fixed and variable adjacent partitioning schemes. However, as the pseudorandom technique incurs high computational complexities, adjacent partitioning schemes were still seen as favorable candidates for PAPR reduction.

  6. Study of Ender’s Nailing in Shaft Femur Fractures of Older Children

    Directory of Open Access Journals (Sweden)

    Ladani HG

    2014-12-01

    Full Text Available Background: Fractures in shaft femur in children are relatively common. Various methods of treating these fractures starting from non operative to methods like closed intramedullary nailing are at our disposal. Traditionally non operative methods are acceptable and find wide acceptance even today in very young children. However in older children certain problems are encountered like failure to control angulation and shortening, prolonged immobilization which causes very much discomfort & the overgrowth phenomenon. In view of above difficulties, closed intramedullary nailing was attempted in older children and adolescents. I have tried to study 23 cases of shaft femur fractures in older children treated by Ender’s nails. Methodology: 22 pts., out of which one having bilateral # shaft femur (total 23 #s with age ranging from 7 to 16 yrs. were studied. 3 pts. having polio limbs studied separately. Fracture was in upper third shaft femur in 5 pts., middle third in 13 pts., lower third in 3pts. & involving more than one region in 2 pts. Fracture was transverse in 6 pts., spiral in 3 pts., oblique in 12 pts.& comminuted in 2 pts.. Results: Average union time was 10 weeks except in polio pts. where it was delayed. No nonunion, no infection. Excellent hip & knee movements in almost all pts. Out of 20 pts. ( except polio pts. limb length was equal in 17 pts., one pt. was having 1 cm. lengthening & 2 pts. were having shortening ( 1cm. & 2 cm.. Conclusion: Results of this study strongly favor the use of Ender’s nailing in shaft femur fractures in older children. Second surgery of implant removal is mandatory. Closed reduction can usually be achieved if surgery is performed earlier.

  7. PTS regulation domain-containing transcriptional activator CelR and sigma factor σ(54) control cellobiose utilization in Clostridium acetobutylicum.

    Science.gov (United States)

    Nie, Xiaoqun; Yang, Bin; Zhang, Lei; Gu, Yang; Yang, Sheng; Jiang, Weihong; Yang, Chen

    2016-04-01

    The phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) regulation domain (PRD)-containing enhancer binding proteins (EBPs) are an important class of σ(54) -interacting transcriptional activators. Although PRD-containing EBPs are present in many Firmicutes, most of their regulatory functions remain unclear. In this study, the transcriptional regulons of about 50 PRD-containing EBPs in diverse Firmicutes species are reconstructed by using a comparative genomic approach, which contain the genes associated with utilization of β-glucosides, fructose/levan, mannose/glucose, pentitols, and glucosamine/fructosamine. We then present experimental evidence that the cel operon involved in cellobiose utilization is directly regulated by CelR and σ(54) (SigL) in Clostridium acetobutylicum. The predicted three CelR-binding sites and σ(54) promoter elements upstream of the cel operon are verified by in vitro binding assays. We show that CelR has an ATPase activity, which is strongly stimulated by the presence of DNA containing the CelR-binding sites. Moreover, mutations in any one of the three CelR-binding sites significantly decreased the cel promoter activity probably due to the need for all three DNA sites for maximal ATPase activity of CelR. It is suggested that CelR is regulated by PTS-mediated phosphorylation at His-551 and His-829, which exerts a positive effect and an inhibitory effect, respectively, on the CelR activity. PMID:26691835

  8. Thermal hydraulic evaluation for an experimental facility to investigate pressurized thermal shock (PTS) in CDTN/CNEN; Avaliacao termo-hidraulica da montagem experimental de choque termico pressurizado do CDTN/CNEN

    Energy Technology Data Exchange (ETDEWEB)

    Palmieri, Elcio T.; Navarro, Moyses A.; Aronne, Ivam D.; Terra, Jose L. [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte, MG (Brazil)

    2002-07-01

    The goal of the work presented in this paper is to provide necessary thermal hydraulics information to the design of an experimental installation to investigate the Pressurized Thermal Shock (PTS) to be implemented at Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN). The envisaged installation has a test section that represents, in a small scale, a pressure vessel of a nuclear reactor. This test section will be heated and then exposed to a PTS in order to evaluate the appearance and development of cracks. To verify the behavior of the temperatures of the pressure vessel after a sudden flood through the annulus, calculations were made using the RELAP5/MOD 3.2.2 gamma code. Different outer radiuses were studied for the annular region. The results showed that the smaller annulus spacing (20 mm) anticipates the wetting of the surface and produces a higher cooling of the external surface, which stays completely wet for a longer time. (author)

  9. New PAPR Reduction in an OFDM System Using Hybrid of PTS-CAPPR Methods with GA Coded Side Information Technique

    Science.gov (United States)

    Pradabpet, Chusit; Yoshizawa, Shingo; Miyanaga, Yoshikazu; Dejhan, Kobchai

    In this paper, we propose a new PAPR reduction by using the hybrid of partial transmit sequences (PTS) and cascade adaptive peak power reduction (CAPPR) methods with side information (SI) technique coded by genetic algorithm (GA). These methods are used in an Orthogonal Frequency Division Multiplexing (OFDM) system. The OFDM employs orthogonal sub-carriers for data modulation. These sub-carriers unexpectedly present a large peak to average power ratio (PAPR) in some cases. A proposed reduction method realizes both the advantages of PTS and CAPPR at the same time. In order to obtain the optimum condition on PTS for PAPR reduction, a quite large calculation cost is demanded and thus it is impossible to obtain the optimum PTS in a short time. In the proposed method, by using the pseudo-optimum condition based on a GA coded SI technique, the total calculation cost becomes drastically reduced. In simulation results, the proposed method shows the improvement on PAPR and also reveals the high performance on bit error rate (BER) of an OFDM system.

  10. New PAPR Reduction in OFDM System Using Hybrid of PTS-APPR Methods with Coded Side Information Technique

    Science.gov (United States)

    Pradabpet, Chusit; Yoshizawa, Shingo; Miyanaga, Yoshikazu; Dejhan, Kobchai

    In this paper, we propose a new PAPR reduction by using the hybrid of a partial transmit sequences (PTS) and an adaptive peak power reduction (APPR) methods with coded side information (SI) technique. These methods are used in an Orthogonal Frequency Division Multiplexing (OFDM) system. The OFDM employs orthogonal sub-carriers for data modulation. These sub-carriers unexpectedly present a large Peak to Average Power Ratio (PAPR) in some cases. In order to reduce PAPR, the sequence of input data is rearranged by PTS. The APPR method is also used to controls the peak level of modulation signals by an adaptive algorithm. A proposed reduction method consists of these two methods and realizes both advantages at the same time. In order to make the optimum condition on PTS for PAPR reduction, a quite large calculation cost must be demanded and thus it is impossible to obtain the optimum PTS. In the proposed method, by using the pseudo-optimum condition with a coded SI technique, the total calculation cost becomes drastically reduced. In simulation results, the proposed method shows the improvement on PAPR and also reveals the high performance on bit error rate (BER) of an OFDM system.

  11. Penicillium chrysogenum Pex5p mediates differential sorting of PTS1 proteins to microbodies of the methylotrophic yeast Hansenula polymorpha

    NARCIS (Netherlands)

    Kiel, Jan A.K.W.; Berg, Marco van den; Bovenberg, Roel A.L.; Klei, Ida J. van der; Veenhuis, Marten

    2004-01-01

    We have isolated the Penicillium chrysogenum pex5 gene encoding the receptor for microbody matrix proteins containing a type 1 peroxisomal targeting signal (PTS1). Pc-pex5 contains 2 introns and encodes a protein of approximately 75 kDa. P. chrysogenum pex5 disruptants appear to be highly unstable,

  12. Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility.

    Directory of Open Access Journals (Sweden)

    Yumi Mizuno

    Full Text Available Peroxisomes are subcellular organelles involved in lipid metabolic processes, including those of very-long-chain fatty acids and branched-chain fatty acids, among others. Peroxisome matrix proteins are synthesized in the cytoplasm. Targeting signals (PTS or peroxisomal targeting signal at the C-terminus (PTS1 or N-terminus (PTS2 of peroxisomal matrix proteins mediate their import into the organelle. In the case of PTS2-containing proteins, the PTS2 signal is cleaved from the protein when transported into peroxisomes. The functional mechanism of PTS2 processing, however, is poorly understood. Previously we identified Tysnd1 (Trypsin domain containing 1 and biochemically characterized it as a peroxisomal cysteine endopeptidase that directly processes PTS2-containing prethiolase Acaa1 and PTS1-containing Acox1, Hsd17b4, and ScpX. The latter three enzymes are crucial components of the very-long-chain fatty acids β-oxidation pathway. To clarify the in vivo functions and physiological role of Tysnd1, we analyzed the phenotype of Tysnd1(-/- mice. Male Tysnd1(-/- mice are infertile, and the epididymal sperms lack the acrosomal cap. These phenotypic features are most likely the result of changes in the molecular species composition of choline and ethanolamine plasmalogens. Tysnd1(-/- mice also developed liver dysfunctions when the phytanic acid precursor phytol was orally administered. Phyh and Agps are known PTS2-containing proteins, but were identified as novel Tysnd1 substrates. Loss of Tysnd1 interferes with the peroxisomal localization of Acaa1, Phyh, and Agps, which might cause the mild Zellweger syndrome spectrum-resembling phenotypes. Our data established that peroxisomal processing protease Tysnd1 is necessary to mediate the physiological functions of PTS2-containing substrates.

  13. Synthesis and Physicochemical Characterization of D-Tagatose-1-phosphate: The Substrate of the Tagatose-1-Phosphate Kinase TagK in the PTS-mediated D-Tagatose Catabolic Pathway of Bacillus licheniformis

    Science.gov (United States)

    Van der Heiden, Edwige; Delmarcelle, Michaël; Simon, Patricia; Counson, Melody; Galleni, Moreno; Freedberg, Darón I.; Thompson, John; Joris, Bernard; Battistel, Marcos D.

    2015-01-01

    We report the first enzymatic synthesis of D-tagatose-1-phosphate (Tag-1P) by the multi-component PEP-dependent:tag-PTS present in tagatose-grown cells of Klebsiella pneumoniae. Physicochemical characterization by 31P and 1H NMR spectroscopy reveals that, in solution, this derivative is primarily in the pyranose form. Tag-1P was used to characterize the putative tagatose-1-phosphate kinase (TagK) of the Bacillus licheniformis PTS-mediated D-Tagatose catabolic Pathway (Bli-TagP). For this purpose, a soluble protein fusion was obtained with the 6 His-tagged trigger factor (TFHis6) of Escherichia coli. The active fusion enzyme was named TagK-TFHis6. Tag-1P and D-fructose-1-phosphate (Fru-1P) are substrates for the TagK-TFHis6 enzyme, whereas the isomeric derivatives D-tagatose-6-phosphate (Tag-6P) and D-fructose-6-phosphate (Fru-6P) are inhibitors. Studies of catalytic efficiency (kcat/Km) reveal that the enzyme specificity is markedly in favor of Tag-1P as substrate. Importantly, we show in vivo that the transfer of the phosphate moiety from PEP to the B. licheniformis tagatose-specific enzyme II (EIITag) in E.coli is inefficient. The capability of the PTS general cytoplasmic components of B. subtilis, HPr and EI, to restore the phosphate transfer is demonstrated. PMID:26159072

  14. A phase I study of paclitaxel as a radiation sensitizer for the treatment of non-small cell lung cancer and mesothelioma

    International Nuclear Information System (INIS)

    Purpose/Objective Paclitaxel exposure of cancer cells in vitro results in a G2/M block in the cell cycle. Paclitaxel also has independent activity against a wide variety of tumors. We report here a phase I study of patients with non-small cell lung cancer and malignant pleural mesothelioma treated with radiation therapy and concurrent paclitaxel. Objectives were to determine the maximum tolerated dose (MTD) of paclitaxel when delivered as a 5-day continuous infusion with concurrent radiotherapy, to assess tumor response and toxicity, and to evaluate the biological effects of paclitaxel in tumor biopsy specimens. Materials and Methods 19 patients (pts.) were enrolled on study. 17 pts. were male and 2 were female. 18 pts. had mesothelioma and 1 had non-small cell lung cancer. Mean age was 59 yrs with a range of 47 to 72 years. One patient did not complete treatment due to progressive disease. Patients who completed treatment received from 5760 to 6300 cGy. Dose volume histography and multiple non-coplanar and non-coaxial fields were used. Patients received a continuous infusion of paclitaxel for 120 hours every three weeks during radiation therapy. The Results MTD of paclitaxel was determined to be 105 mg/m2 delivered as a 120-hour continuous infusion. The dose-limiting toxicity of paclitaxel was neutropenia at 120 mg/m2 given over 120 hrs. 13 patients were assessable for local control; 4 pts. are too early to evaluate and 2 pts. did not return for follow-up. (11(13)) pts. achieved local control. 3 of 13 patients are free of disease. 10 tumor biopsies were taken from 4 mesothelioma pts. Biopsies were taken prior to the paclitaxel infusion and then during the infusion. A modest G2/M block was observed in only 1 of the 5 specimens taken during the paclitaxel infusion. Conclusions This study demonstrates that paclitaxel can be safely delivered as a 120-hour continuous infusion at 105 mg/m2 with concurrent thoracic radiotherapy. However, the biologic effect of paclitaxel

  15. National Children's Study Dietary Assessment Workshop

    Science.gov (United States)

    The National Children's Study dietary assessment workshop was an opportunity for experts in dietary assessment methodology to gather and discuss the current state of knowledge about methodologies used to assess dietary intake during pregnancy, lactation, infancy, childhood, and adolescence.

  16. CLINICAL EFFICACY OF THE DRUG STRUCTUM IN OSTEOARTHRITIS THERAPY (results of multicenlral clinical study in Russia

    Directory of Open Access Journals (Sweden)

    V A Nassonova

    2001-01-01

    Full Text Available Objective. Study of the efficacy and tolerability of Structum in pts with gonarthritis and coxarthritis during 6 months therapy. Material. Open multicentral study included off -patients of both sexes with osteoarthritis (ОЛ of knee and hip joints with obvious pain syndrome - pain in walking 30 mm and more on visual analog scale, functional Lesquene index more or equal to 4 and less or equal toll, regular NSAIDs taking for 30 days for the last 3 months, radiological I-II-III OA stage according Kellgren-Lawrence and consent of the patient for the study. Total number of pts included was 555 and 192 out of them were experimental group and 363 - controls. Pts from experimental group had Structum - three capsules in the morning and 3 capsules in the evening during meals (one capsule - 250 mg for 3 weeks, then 2 capsules in the morning and 2 in the evening for 21 weeks. Clinical examination of pts was done after the third and sixth month of the treatment. Results. During Structum therapy reliable lessening of pain syndrome in knee and hip joints, improvement of articular function, decrease of NSAIDs dosage or their full cancellation were demonstrated. It was noticed that the assessment of clinical Structum efficacy and tolerability bu physician and patient coincided. Conclusion. Structum (chondroitin sulfate is a new effective drug for treatment of osteoarthritis of knee and hip joints with high clinical efficacy and good tolerability

  17. A PhD abstract presentation on Cluster Framework for Internet of People, Things and Services (IoPTS)

    DEFF Research Database (Denmark)

    Shinde, Gitanjali; Olesen, Henning

    2014-01-01

    The Internet of Things (IoT) is a revolutionary technology, where devices around us are capable of sensing, reacting, responding and working autonomously to provide services to the users /people, e.g. smart homes, enterprise, utilities and e-Health. In the IoT paradigm, every device will be conne......The Internet of Things (IoT) is a revolutionary technology, where devices around us are capable of sensing, reacting, responding and working autonomously to provide services to the users /people, e.g. smart homes, enterprise, utilities and e-Health. In the IoT paradigm, every device...... will be connected to the Internet to provide services to the user. Bringing this together makes it relevant to talk about the "Internet of People, Things and Services (IoPTS)."However, managing such a huge number of devices is a major challenge for IoPTS. In any given context, a number of devices will work together...... announce their services to those who need them. Users can access these services with the help of widely interconnected devices. To access the services user has to provide some personal data. In IoPTS services are large in numbers, and to protect the user data there is a need to ensure that these services...

  18. Development of Pneumatic Transfer Irradiation Facility (PTS no.1) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J

    2008-03-15

    A pneumatic transfer system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide and a delayed neutron counting system. The pneumatic transfer system (PTS no.1) involving a manual system and an semiautomatic system were reconstructed with new designs of a functional improvement at the HANARO research reactor in 2006. In this technical report, the conception, design, operation and control of these system (PTS no.1) was described. Also the experimental results and the characteristic parameters measured by a mock-up test, a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  19. Development of Pneumatic Transfer Irradiation Facility (PTS no.3) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J

    2008-04-15

    A pneumatic transfer system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide. The pneumatic transfer irradiation system (PTS no.3) involving a manual system and an semi-automatic system were reconstructed with new designs of a functional improvement at the HANARO research reactor and NAA laboratory of RI building in 2006. In this technical report, the design, operation and control of these system (PTS no.3) was described. Also the experimental results and the characteristic parameters measured from a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  20. Development of Pneumatic Transfer Irradiation Facility (PTS no.2) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J

    2008-03-15

    A pneumatic transfer irradiation system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide and a delayed neutron counting system. The pneumatic transfer irradiation system (PTS no.2) involving a manual system and an automatic system for delayed neutron activation analysis (DNAA) were reconstructed with new designs of a functional improvement at the HANARO research reactor in 2006. In this technical report, the conception, design, operation and control of PTS no.2 was described. Also the experimental results and the characteristic parameters measured by a mock-up test, a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, automatic operation control by personal computer, delayed neutron counting system, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  1. Characterization of injection wells in a fractured reservoir using PTS logs, Steamboat Hills Geothermal Field, Nevada, USA

    Energy Technology Data Exchange (ETDEWEB)

    Goranson, Colin; Combs, Jim

    1995-01-26

    The Steamboat Hills Geothermal Field in northwestern Nevada, about 15 km south of Reno, is a shallow (150m to 825m) moderate temperature (155 C to 168 C) liquid-dominated geothermal reservoir situated in highly-fractured granodiorite. Three injection wells were drilled and completed in granodiorite to dispose of spent geothermal fluids from the Steamboat II and III power plants (a 30 MW air-cooled binary-type facility). Injection wells were targeted to depths below 300m to inject spent fluids below producing fractures. First, quasi-static downhole pressure-temperature-spinner (PTS) logs were obtained. Then, the three wells were injection-tested using fluids between 80 C and 106 C at rates from 70 kg/s to 200 kg/s. PTS logs were run both up and down the wells during these injection tests. These PTS surveys have delineated the subsurface fracture zones which will accept fluid. The relative injectivity of the wells was also established. Shut-in interzonal flow within the wells was identified and characterized.

  2. Geology, Surficial - CLAY_ILITH_PTS_IN: Total Thickness of Clay in Indiana, Derived from the iLITH Water-Well Database (Indiana Geological Survey, Point Shapefile)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — CLAY_ILITH_PTS_IN is a point shapefile that shows total thickness of clay, as derived from logs of water wells in the state of Indiana. (It presents the source data...

  3. A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes.

    Science.gov (United States)

    Fortnum, Heather; Ukoumunne, Obioha C; Hyde, Chris; Taylor, Rod S; Ozolins, Mara; Errington, Sam; Zhelev, Zhivko; Pritchard, Clive; Benton, Claire; Moody, Joanne; Cocking, Laura; Watson, Julian; Roberts, Sarah

    2016-01-01

    with confirmed hearing impairment were older at referral in the site with SES (mean age difference 0.47 years, 95% CI 0.24 to 0.70 years; p < 0.001). Parental responses revealed that the consequences to the family of the referral process are minor. A SES programme is unlikely to be cost-effective and, using base-case assumptions, is dominated by a no screening strategy. A SES programme could be cost-effective if there are fewer referrals associated with SES programmes or if referrals occur more quickly with SES programmes. CONCLUSIONS A SES programme using the PTS or HC screener is unlikely to be effective in increasing the identified number of cases with hearing impairment and lowering the average age at identification and is therefore unlikely to represent good value for money. This finding is, however, critically dependent on the results of the observational study comparing Nottingham and Cambridge, which has limitations. The following are suggested: systematic reviews of the accuracy of devices used to measure hearing at school entry; characterisation and measurement of the cost-effectiveness of different approaches to the ad-hoc referral system; examination of programme specificity as opposed to test specificity; further observational comparative studies of different programmes; and opportunistic trials of withdrawal of SES programmes. TRIAL REGISTRATION Current Controlled Trials ISRCTN61668996. FUNDING This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 36. See the NIHR Journals Library website for further project information. PMID:27169435

  4. A manual therapy intervention improves symptoms in patients with carpal tunnel syndrome: a pilot study.

    Science.gov (United States)

    Maddali Bongi, Susanna; Signorini, Massimo; Bassetti, Massimo; Del Rosso, Angela; Orlandi, Martina; De Scisciolo, Giuseppe

    2013-05-01

    In carpal tunnel syndrome (CTS), manual therapy interventions (MTI) reduce tissue adhesion and increase wrist mobility. We evaluated the efficacy of a MTI in relieving CTS signs and symptoms. Twenty-two CTS patients (pts) (41 hands) were treated with a MTI, consisting in 6 treatments (2/week for 3 weeks) of soft tissues of wrist and hands and of carpal bones. Pts were assessed for hand sensitivity, paresthesia, hand strength, hand and forearm pain, night awakening; Phalen test, thenar eminence hypotrophy and Boston Carpal Tunnel Questionnaire (BCTQ) Symptom Severity Scale (SSS) and Functional Status Scale (FSS). Median nerve was studied by sensory nerve conduction velocity (SNCV) and distal motor latency (DML). CTS was scored as minimal, mild, medium, severe and extreme. We considered as control group the same pts assessed before treatment: at baseline (T0a) and after 12 weeks (T0b). Pts were evaluated at the end of treatment (T1) and after 24-week (T2) follow-up. At T0b, versus T0a, forearm pain and Phalen test positivity were increased and hand strength reduced (p < 0.05). BCTQ-SSS and BCTQ-FSS scores improved at T1 versus T0b (p < 0.05) with the amelioration maintained at T2. At T1, the number of pts with paresthesia, night awakening, hypoesthesia, Phalen test, hand strength reduction and hand sensitivity was reduced with the lacking of symptoms maintained at T2 (p < 0.05). No changes in SNCV, DML and CTS scoring were shown. MTI improved CTS signs and symptoms, with benefits maintained at follow-up. Thus, it may be valid as a conservative therapy.

  5. STUDY OF THE THERMAL STRATIFICATION IN PWR REACTORS AND THE PTS (PRESSURIZED THERMAL SHOCK) PHENOMENON

    OpenAIRE

    ROMERO HAMERS, ADOLFO

    2014-01-01

    In the event of hypothetical accident scenarios in PWR, emergency strategies have to be mapped out, in order to guarantee the reliable removal of decay heat from the reactor core, also in case of component breakdown. One essential passive heat removal mechanism is the reflux condensation cooling mode. This mode can appear for instance during a small break loss-of-coolant-accident (LOCA) or because of loss of residual heat removal (RHR) system during mid loop operation at plant outage after th...

  6. Assessing Vocal Performances Using Analytical Assessment: A Case Study

    Science.gov (United States)

    Gynnild, Vidar

    2016-01-01

    This study investigated ways to improve the appraisal of vocal performances within a national academy of music. Since a criterion-based assessment framework had already been adopted, the conceptual foundation of an assessment rubric was used as a guide in an action research project. The group of teachers involved wanted to explore thinking…

  7. Improved PTS for PAPR Reduction in OFDM System%抑制OFDM系统PAPR的PTS算法改进

    Institute of Scientific and Technical Information of China (English)

    汪锦州

    2009-01-01

    部分传输序列(PTS)是一种降低OFDM信号的峰值平均功率比(PAPR)的有效方法.PTS采用是在子序列中添加旋转相位因子[0,2 π).通过对OFDM信号相位分布情况进行研究,本文提出一种改进的PTS方法.改进点在其相位旋转因子的选择上,采用每个子块乘以非均匀分布的旋转因子.

  8. Monitoring study and impact assessment

    OpenAIRE

    Budidarsono, Suseno; Rahmanulloh, Arif

    2008-01-01

    Report on the progress of socio-economic objective of LTRP 5 in Indonesia. The objectives were: (1) Identify vegetable cultivation technology on agroforestry system that socially acceptable, economically feasible, and affordable; (2) Provide information on the level adoption of vegetable cultivation technology in agroforestry system and (3)Assess impacts of technology adoption on farmers' incomes.

  9. 冠心病并糖尿病患者氯吡格雷治疗后PTS 分子标志物变化及意义%Changes and Significance of PTS Molecular Markers after Treatment of Clopidogrel in Coronary Heart Disease Patients Combined with Diabetes

    Institute of Scientific and Technical Information of China (English)

    万妮娜; 马建林; 吴明; 马立宁; 李斌

    2015-01-01

    Objective To observe the changes and significance of prethrombotic state(PTS)molecular markers after treatment of clopidogrel in coronary heart disease(CHD)patients combined with non - insulin dependent diabetes mellitus(NIDDM). Methods PTS molecular markers were measured in 36 patients with stable angina(SA),38 pa-tients with unstable angina(UA),40 UA patients combined with NIDDM,who were given platelet ADP receptor antag-onist clopidogrel 75 mg/ d. PTS molecular markers were reexamined and clopidogrel resistance was measured 10 days later. Results ①There were more obvious changes of PTS molecular markers in patients with UA,especially in those combined with NIDDM before clopidogrel treatment. ②There were significant improvement of PTS molecular markers in patients in three groups after clopidogrel treatment. ③There were 18 cases with clopidogrel resistance and 96 cases without clopidogrel resistance in 114 cases. There were significant improvement of PTS in patients without clopidogrel resistance. However,there was no significant difference of PTS molecular markers before and after treatment in patients with clopidogrel resistance. Conclusion PTS in CHD patients combined with diabetes is more serious than CHD pa-tients without diabetes. PTS in patients with UA is more serious than that in patients with SA. PTS in patients with all types of CHD can be intervened by clopidogrel therapy. However,it is not effective in patients with clopidogrel resist-ance,which may be an important cause of poor prognosis in these patients.%目的:观察冠心病(CAD)并2型糖尿病(NIDDM)患者经过血小板 ADP 受体拮抗剂治疗后血栓形成前状态(PTS)分子标志物的变化及意义。方法对36例稳定性心绞痛(SA)、38例不稳定性心绞痛(UA)、40例 UA 合并 NIDDM 患者的 PTS 分子标志物进行检测,均给予血小板 ADP 受体拮抗剂氯吡格雷75 mg/ d,10 d 后复查 PTS 分子标志物,同时测定有无氯吡

  10. An Assessment Tool Translation Study

    OpenAIRE

    Buchanan, Joan L.; Andres, Patricia L.; Haley, Stephen M; Paddock, Susan M.; Zaslavsky, Alan M.

    2003-01-01

    Policymakers hoped to substitute a new, multi-purpose, functional assessment instrument, the minimum data set post-acute care (MDS-PAC), into the planned prospective payment system (PPS) for inpatient rehabilitation hospitals. PPS design requires a large database linking treatment costs with measures of the need for care, so the PPS was designed using the functional independence measure (FIM™) database linked to Medicare hospital claims. An accurate translation from the MDS-PAC items to FIM™-...

  11. Complex assessment of regional hemodynamics with tetrapolar rheography and laser Doppler fluometry in patients with low back pain syndrome

    Directory of Open Access Journals (Sweden)

    D. A. Shemetov

    2003-01-01

    Full Text Available Objective. To assess hemodynamic disturbances in pts with low back pain syndrome (LBPS. Material and methods. 57 pts with LBPS were examined (12 female and 45 male aged 18 to 53 years (mean age 36,7 years. Spine osteochondritis was diagnosed in most of them. 34 had subacute and 23 - chronic LBPS course. In 32 pts peripheral hemodinamic indices were examined with tetrapolar rheo- vasography by “ARM-RhEO" apparatus. In 25 pts total local blood flow was assessed in pain points with laser-Doppler fluometry (LDF-2 apparatus. 35 healthy individuals of comparable age and sex were included in control group. Results. 77% of pts showed small vessels tone decrease most prominent in pts with subacute LBPS course. Arterial wall elasticity diminution was revealed in 63% of cases, significant reduction of blood filling level - in 82%, venous flow-out obstacle - in 87%. There was a connection between degree of local blood flow increase in back pain points and (PI score: 0,19 V in pts with PI>60 u and 0,13 V in pts with PK40 u (in control group - 0,08 V, p<0,05 what shows perifocal edema in most painful points. Conclusion. Revealed regional hemodynamic and microcirculation disturbances can objectively confirm participation of hemodynamic disturbances in pain syndrome genesis and serve as a basis for perfection of LBPS treatment methods.

  12. Assessing observational studies of medical treatments

    Directory of Open Access Journals (Sweden)

    Butani Yogita

    2005-09-01

    Full Text Available Abstract Background Previous studies have assessed the validity of the observational study design by comparing results of studies using this design to results from randomized controlled trials. The present study examined design features of observational studies that could have influenced these comparisons. Methods To find at least 4 observational studies that evaluated the same treatment, we reviewed meta-analyses comparing observational studies and randomized controlled trials for the assessment of medical treatments. Details critical for interpretation of these studies were abstracted and analyzed qualitatively. Results Individual articles reviewed included 61 observational studies that assessed 10 treatment comparisons evaluated in two studies comparing randomized controlled trials and observational studies. The majority of studies did not report the following information: details of primary and ancillary treatments, outcome definitions, length of follow-up, inclusion/exclusion criteria, patient characteristics relevant to prognosis or treatment response, or assessment of possible confounding. When information was reported, variations in treatment specifics, outcome definition or confounding were identified as possible causes of differences between observational studies and randomized controlled trials, and of heterogeneity in observational studies. Conclusion Reporting of observational studies of medical treatments was often inadequate to compare study designs or allow other meaningful interpretation of results. All observational studies should report details of treatment, outcome assessment, patient characteristics, and confounding assessment.

  13. Collaborative Assessment: Middle School Case Study

    Science.gov (United States)

    Parkison, Paul T.

    2014-01-01

    Utilizing a participant observer research model, a case study of the efficacy of a collaborative assessment methodology within a middle school social studies class was conducted. A review of existing research revealed that students' perceptions of assessment, evaluation, and accountability influence their intrinsic motivation to learn. A…

  14. Dietary assessment methods in epidemiologic studies

    OpenAIRE

    Shim, Jee-Seon; Oh, Kyungwon; Kim, Hyeon Chang

    2014-01-01

    Diet is a major lifestyle-related risk factor of various chronic diseases. Dietary intake can be assessed by subjective report and objective observation. Subjective assessment is possible using open-ended surveys such as dietary recalls or records, or using closed-ended surveys including food frequency questionnaires. Each method has inherent strengths and limitations. Continued efforts to improve the accuracy of dietary intake assessment and enhance its feasibility in epidemiological studies...

  15. Study on Assessment of Mine Environments

    Institute of Scientific and Technical Information of China (English)

    WU Qiang; LI Wei; LI Ruijun

    2008-01-01

    Mine environmental evaluation is the key to mine environmental study. On the basis of the characteristics of the mine environmental problems, they are classified into (1) three wastes problem, (2) ground distortion, (3) contradiction among mine drainage, water supply, ecological environment,(4) desertification, and (5) soil erosion. The evaluation is the basis of mine environmental problem classification and investigation, mine environmental rehabilitation, and the information system constructed can be used for subsequent research of evaluation techniques. A synthetic assessment of the 5 kinds of mine environmental problems can be divided into single-factor or multi-factor synthetic assessments; while by the viewpoint of time, the mine environmental assessment can be classified as the historical assessment, the current status assessment and the forecasting assessment.

  16. Viscoplastic-dynamic analyses of small-scale fracture tests to obtain crack arrest toughness values for PTS conditions

    International Nuclear Information System (INIS)

    Reliable predictions of crack arrest at the high upper shelf toughness conditions involved in postulated pressurized thermal shock (PTS) events require procedures beyond those utilized in conventional fracture mechanics treatments. To develop such a procedure, viscoplastic-dynamic fracture mechanics finite element analyses, viscoplastic material characterization testing, and small-scale crack propagation and arrest experimentation are being combines in this research. The approach couples SwRI's viscoplastic-dynamic fracture mechanics finite element code VISCRK with experiments using duplex 4340/A533B steel compact specimens. The experiments are simulated by VISCRK computations employing the Bodner-Partom viscoplastic constitutive relation and the nonlinear fracture mechanics parameter T. The goal is to develop temperature-dependent crack arrest toughness values for A533B steel. While only room temperature KIa values have been obtained so far, these have been found to agree closely with those obtained from wide plate tests. (author)

  17. Assessing the Academic Benefit of Study Abroad

    Science.gov (United States)

    Cisneros-Donahue, Teresa; Krentler, Kathleen A.; Reinig, Bruce; Sabol, Karey

    2012-01-01

    Study abroad is a growing phenomenon in higher education. Although such growth is typically lauded, efforts to measure the impact of international experiences on student learning have been limited. This study assesses the academic benefit of a study abroad program, offered by a U.S. university, with measures of self-reported learning. Study abroad…

  18. Myocardial perfusion assessed by contrast echocardiography and single photon emission computed tomography in the evaluation of patients with acute chest pain and normal electrocardiogram

    International Nuclear Information System (INIS)

    Aim : Evaluation of diagnostic accuracy of myocardial contrast echocardiography (MCE) in comparison with single-photon emission computed tomography (SPECT) for the detection of myocardial ischemia in patients with acute chest pain. Material and Methods : Eighteen patients (pts) with chest pain lasting ≥30 minutes, occurring within 6 hours of emergency room presentation and a normal or no diagnostic electrocardiogram were studied. Pts underwent rest MCE and SPECT. For both exams myocardial perfusion was assessed in the same 7 segments (apical, anterior, inferior, anteroseptal, inferoseptal, lateral and posterior) of left ventricle. A total of 126 segments were analyzed. Images were classified as positive for ischemia if they had a perfusion defect. Coronary angiography was performed if MCE or SPECT images were classified as positive for ischemia or by clinical indication. Otherwise the patients underwent stress SPECT. Significant coronary artery disease (CAD) was defined as ≥70% stenosis in a major coronary artery or its branches. Final diagnosis of an acute coronary event (ACE) was established in the presence of positive findings in MCE or SPECT in addition to significant CAD in the corresponding territory. Kappa statistics were calculated to evaluate the concordance between MCE and SPECT. κ values of ≤0.4, >0.4 and >0.7 indicate fair, good and excellent agreement, respectively. Results: Thirteen out of 18 pts underwent coronary angiography (seven pts had positive findings on SPECT, 2 on MCE, 2 on both exams and 1 had clinical indication). Significant CAD was detected on six. Five pts underwent stress SPECT and no perfusion defect was detected. Therefore, six pts (33.3%) had an ACE and 12 (66.6%) had not. There were no statistical differences between groups according to age, gender, duration of pain, free pain interval, presence of risk factors and antecedents. Concordance between MCE and SPECT for evaluation of perfusion defects showed a ? coefficient of 0

  19. Assessment of joint pain in teenagers with juvenile arthritis

    Directory of Open Access Journals (Sweden)

    T A Shelepina

    2009-01-01

    Full Text Available Assessment of joint pain in teenagers with juvenile arthritisObjective. To assess mean total pain score in teenagers with juvenile arthritis (JA and its values in groups differing on sex, variant of course, activity measures, degree of functional disturbances. To assess advisability of application of these parameters in real clinical practice. Material and methods. 73 pts with JA (mean age 14,7±1,7 years, mean disease duration7,2±4,4 years were included. 18 from them had systemic, 42 – polyarticular and 13 – olygoarticular variant. 16 pts were examined repeatedly with interval exceeding one year. Total quantity of examinations was 94. 17 pts were examined at admission and at discharge. Pain was measured on visual analog scale (VAS and on McGill Pain Questionnaire (83 examinations including 3 scale: sensor (description of pain, affective (their influence on emotional state and evaluative (verbal assessment of pain intensity. General health assessment on VAS was performed in 59 pts (in 8 from them at admission and at discharge. Summary mean measures and their values in groups differing in sex, course variant, activity measure, functional class at pts admission to and at discharge from the Institute of Rheumatology of RAMS. Statistical treatment was performed with Biomed program(descriptive statistic, χ2, Student’s pared test. Results. Mean pain score on VAS in all teenagers with JA was 31,3±17,3. It was significantlyhigher in boys with systemic variant (in comparison with polyarticular, in pts with ESR elevation above 30, in pts with functional class 3 and higher at admission to the department. Pain score was significantly lower in pts with olygoarticular variant in comparison with mean value and with value in polyarthritis. Pain above 70 mm on VAS was found in pts with polyarticular damage in systemic and polyarticular variants in active phase of the disease and in severe functional disability. Summated (on sensor and affective scales

  20. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...... Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark....

  1. 6-PTS 并联机器人机构逆向运动学分析与仿真*1%Inverse kinematics analysis and simulation of 6-PTS parallel robot

    Institute of Scientific and Technical Information of China (English)

    张锋涛

    2015-01-01

    Objective—To put forward the algorithm of kinematic relationship between the parallel robot components.Methods—The composite joint of 6-PTS parallel robot's structure was equivalently processed into single DOF (degree of freedom)joint,then D-H (Denavic-Hartenberg)method was used to define the local coordinate system and kinematic parameters of each linkage.Finally mecha-nism constraint equations was established according to the motion equivalence condition and the solu-tion was obtained with reverse homogeneous transformation.Results and Conclusion—The variables of all joint and the position of each linkage were solved successively.On this basis,the influence coeffi-cient theory was utilized to build the transitive relationships of the velocity and acceleration between moving platform and each linkage to provide the basis for the dynamic modeling and control problem of the mechanism.%目的:提出建立并联机器人构件之间运动学关系的算法。方法将6-PTS 并联机器人机构的复合关节等效地处理成单自由度关节,利用 D-H(Denavic-Hartenberg)方法定义每个连杆的局部坐标系和运动学参数,根据运动等同性条件建立机构约束方程,利用逆向齐次变换的方法求解。结果与结论依次求解出全部关节变量和每个连杆的位置表示,在此基础上,应用影响系数理论,建立了动平台与每个连杆之间的速度和加速度的传递关系,为该机构的动力学建模及控制等问题提供了基础。

  2. Environmental Impact Assessment Studies in Additive Manufacturing

    OpenAIRE

    Kerbrat, Olivier; Le Bourhis, Florent; MOGNOL, Pascal; Hascoët, Jean-Yves

    2016-01-01

    International audience This chapter focuses on the environmental studies in additive manufacturing. For a cleaner production, environmental impacts that occur during the manufacturing phase should be assessed with accuracy. First, the literature on all the studies led to the characterization of the environmental impact of additive manufacturing processes. The studies on electric energy consumption of these processes are analyzed here, and then some studies taking into account raw material ...

  3. Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies

    Institute of Scientific and Technical Information of China (English)

    Jiang-quan ZHOU; Zhi-qiang TANG; Jin-nan ZHANG; Jing-cheng TANG

    2006-01-01

    Aim: To study the in vivo and in vitro metabolism and the effect of para-toluene-sulfonamide (PTS) on cytochrome P450 enzymes (CYP450). Methods: Total C YP450 and microsome protein content were determined after iv pretreatment of rats with PTS. CYP-specific substrates were incubated with rat liver microsomes. Specific CYP isoform activities were determined by using HPLC. CYP chemical inhibitors added to the incubation mixture were used to investigate the principal CYP isoforms involved in PTS metabolism. The effect of PTS on CYP isoforms was investigated by incubating PTS with specific substrates. Results: The groups treated with 33 and 99 mg/kg per d PTS, respectively, had a total CYP content of 0.66±0.17 and 0.60±0.12 nmol/mg. The Km and Vmax were 92.2 μmol/L and 0.0137 nmol/min per mg protein. CYP2C7, CYP2D1 and CYP3A2 might contribute to PTS metabolism in the rat liver. The inhibitory effects of sulfaphenazole and ketoconazole on PTS metabolism were shown to have a mixed mechanism, whereas PTS metabolism was inhibited noncompetitively by quinidine. PTS had little effect on the activities of the selected CYP isoforms. Conclusion: Generally speaking, it is relatively safe for PTS to be co-administered with other drugs. However, care should be taken when administering PTS with CYP inhibitors and the substrates of CYP2C, CYP2D and CYP3A.

  4. A Study of Career Planning Assessments

    OpenAIRE

    Firkola, Peter

    2007-01-01

    This paper provides an overview of career planning assessments. Background on key career concepts is first introduced. A number of career planning assessments are then examined. These assessments included reviewing ones personal history, interest inventories, values assessments, personality assessments, and aptitude tests. The importance and limitations of these career assessments is then discussed.

  5. Risk Assessment Study for Storage Explosive

    Directory of Open Access Journals (Sweden)

    S. S. Azhar

    2006-01-01

    Full Text Available In Malaysia, there has been rapidly increasing usage in amount of explosives due to widely expansion in quarrying and mining industries. The explosives are usually stored in the storage where the safety precaution had given high attention. As the storage of large quantity of explosive can be hazardous to workers and nearby residents in the events of accidental denotation of explosives, a risk assessment study for storage explosive (magazine had been carried out. Risk assessment study had been conducted in Kimanis Quarry Sdn. Bhd, located in Sabah. Risk assessment study had been carried out with the identification of hazards and failure scenarios and estimation of the failure frequency of occurrence. Analysis of possible consequences of failure and the effects of blast waves due to the explosion was evaluated. The risk had been estimated in term of fatalities and eardrum rupture to the workers and public. The average individual voluntary risk for fatality to the workers at the quarry is calculated to be 5.75 x 10-6 per person per year, which is much lower than the acceptable level. Eardrum rupture risk calculated to be 3.15 x 10-6 per person per year for voluntary risk. There is no involuntary risk found for fatality but for eardrum rupture it was calculated to be 6.98 x 10-8 per person per year, as given by Asian Development Bank.

  6. ANALISIS DAMPAK OTONOMI DAERAH TERHADAP STRATEGI PENGEMBANGAN PERGURUAN TINGGI SWASTA (PTS DI KABUPATEN SLEMAN

    Directory of Open Access Journals (Sweden)

    Rudy Badrudin

    2008-12-01

    Full Text Available This research analyze the effect of regional autonomy to the interest of college’s student candidate to continue studying in Sleman Regency which research’s samples for major program’s chosen was Accounting, Management, and Economics in UII, UAJY, UPNVY, and STIE YKPN. The result of research with Boston Consulting Group (BCG Matrix shows that each major program in four universities and college was in different quadrant. Therefore, each university and college has to choose different development strategic specifically even for each major programs in each university and college, so that the major programs in four universities and college in Sleman Regency could grow and rise.

  7. Geology, Surficial - SAND_ILITH_PTS_IN: Total Thickness of Sand and Gravel in Indiana, Derived from the iLITH Water-Well Database (Indiana Geological Survey, Point Shapefile)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — SAND_ILITH_PTS_IN is a point shapefile that shows total thickness of sand, as derived from logs of water wells in the state of Indiana. (It presents the source data...

  8. 用部分相关-PTS方法降低OFDM系统的PAPR%Reduction of the PAPR of OFDM systems by partial-correlation-PTS method

    Institute of Scientific and Technical Information of China (English)

    贾莹莹; 杨霖; 王田; 胡武君

    2014-01-01

    文章介绍了降低 OFDM (正交频分复用)系统PAPR (峰均功率比)的各种技术,对PTS (部分传输序列)技术进行了改进,提出了部分相关-PTS方法。该方法的基本思想是经过基带调制数据分割之后,使得除第一个数据块之外的其他每一个数据块分别与第一个数据块做互相关运算,然后按照传统PTS方法继续处理部分相关的数据子块。在接收端,根据每一个子块(第一个子块除外)与第一个子块互相关值的正负来判断该子块所乘的旋转相位,无需传输边带信息就可以恢复出原始信号。仿真结果验证了该方法的有效性。%This paper introduces various technologies for the reduction of the Peak-to-Average Power Ratio (PAPR)of Orthog-onal Frequency Division Multiplexing (OFDM)systems,modifies the conventional Partial Transmit Sequence (PTS)technolo-gy and proposes a partial-correlation-PTS method.The fundamental idea of this method is that after the original modulated fre-quency domain signals are divided into several data blocks,every other data block than the first one does cross-correlation cal-culation with the first data block and then continue to handle partial-correlation data subblocks in accordance with the conven-tional PTS method.At the receiver end,the multiplied rotation phase of each data subblock except the first one is decided ac-cording to the positive or negative property of the cross-correlation value of that subblock with the first data subblock.Thus the original signals can be recovered without transmitting sideband information.The effectiveness of the partial-correlation-PTS method is verified by the simulation results.

  9. Hegemonic Masculinity in Sport Education: Case Studies of Pre-Service Physical Education Teachers with Teaching Orientations

    Science.gov (United States)

    Chen, YuChun; Curtner-Smith, Matthew D.

    2015-01-01

    Previous research had indicated that pre-service teachers (PTs) with coaching orientations reinforced sexism and masculine bias while employing the sport education (SE) model. The purpose of the current study was to examine whether or not and the degree to which SE delivered by PTs with teaching orientations served to combat or reinforce sexism…

  10. The Healthy Communities Study Nutrition Assessments

    Science.gov (United States)

    Ritchie, Lorrene D.; Wakimoto, Patricia; Woodward-Lopez, Gail; Thompson, Frances E.; Loria, Catherine M.; Wilson, Dawn K.; Kao, Janice; Crawford, Patricia B.; Webb, Karen L.

    2015-01-01

    Multifaceted community interventions directed at improving food environments are emerging, but their impact on dietary change and obesity prevalence has not been documented adequately. The Healthy Communities Study (HCS) is seeking to identify characteristics and combinations of programs and policies that are associated with children’s diets and obesity-related outcomes in various types of communities across the U.S. The purpose of this paper is to describe the methods used in 2013–2015 in the HCS to assess dietary intake, school nutrition environments, and other nutrition-related behaviors. The conceptual framework of the HCS is based on the socioecological model and behaviors shown in previous studies to be related to obesity in children-guided selection of domains. Nine domains were identified as essential measures of nutrition in the HCS: (1) intake of selected foods and beverages; (2) food patterns and behaviors; (3) social support; (4) home environment; (5) school environment; (6) community environment; (7) breastfeeding history; (8) household food insecurity; and (9) dieting behaviors and body image. Children’s dietary intake was assessed using a dietary screener and up to two automated 24-hour recalls. Dietary-related behaviors were assessed by a survey administered to the parent, child, or both, depending on child age. School nutrition measures were obtained from a combination of school staff surveys and researcher observations. Information from these measures is expected to contribute to a better understanding of “what is working” to improve the dietary behaviors that are likely to prevent obesity and improve health in children. PMID:26384936

  11. Hydrogen Mixing Studies (HMS) assessment manual

    International Nuclear Information System (INIS)

    This report documents some calculations performed to assess the Hydrogen Mixing Studies (HMS) code. Results are presented first for some analytical test problems, including laminar flow and mass diffusion. The von Karman vortex street problem and the Sandia FLAME Facility and Heiss Dampf Reaktor (HDR) containment facility test problems are then discussed. For the analytical problems, the code gave results that agree exceptionally well with the analytical solutions. Calculations for the von Karman vortex street problem were performed at selected Reynolds numbers for several obstacle types. The computed flow patterns agree well with experimental observations-specifically the occurrence of a vortex street (double row of vortices) above a critical Reynolds number. Calculations for the von Karman vortex street problem were performed at selected Reynolds numbers for several obstacle types. The computed flow patterns agree well with experimental observations-specifically the occurrence of a vortex street (double row of vortices) above a critical Reynolds number. The last assessment problem involves modeling the experiment T31.5. The experiment was carried out in the HDR containment building, which is a large, multi-compartment facility (11 300 m3 free volume in 72 compartments). In the experiment, a steam-water mixture was first injected into the containment to simulate a large-break blowdown of a pressure vessel, and then superheated steam was injected that was followed by a release of helium-hydrogen light gas. The calculated results (pressure, temperature, and gas concentrations) agree reasonably well with the experimental data

  12. Assessment in translation studies : research needs

    OpenAIRE

    Martínez, Nicole; Hurtado Albir, Amparo

    2001-01-01

    On the whole, most research into assessment in translation only concentrates on one area — evaluation of translations of literary and sacred texts — and other areas are ignored. In fact, this field of research includes two other areas, each with its own characteristics: assessment of professionals at work and assessment of trainee translators.Starting with this presupposition, we describe the three areas and analyze the notion of translation assessment, so as to define the characteristics of ...

  13. 恰希玛核电厂压力容器各关键部位在PTS瞬态下的温度场研究%Research on PTS Transient Temperature Field of Key Position of RPV for Chashma Nuclear Power Plant

    Institute of Scientific and Technical Information of China (English)

    左巧林; 秋穗正; 王明军

    2016-01-01

    The pressurized thermal shock (PTS) in the assessment of life extension of a nuclear power plant should be paid much attention to .For Chashma NPP No .1 unit ,a complete CFD model for RPV and its internals was established .Coolant velocity and temperature fields in RPV were simulated during normal state ,and the results are con-sistent with experimental data . The coolant thermal-hydraulic characteristics in the RPV nozzle and the downcomer under SGTR transient were also studied in detail .The results were compared with the calculation results by RELAP5 code , and the good agreement is achieved between them .The present research could be useful for the calcu-lation and analysis in RPV aging management evaluation .%承压热冲击现象在核电厂延寿评估中应被重点关注.本文针对恰希玛核电厂1号机组的压力容器及堆内构件建立了完整的C FD模型,计算了正常工况下压力容器内冷却剂的速度场和温度场分布,计算结果与试验结果符合良好.本文详细研究了蒸汽发生器传热管破裂事故工况下压力容器接管及下降段中冷却剂的热工水力特性,并将计算结果与RELAP5计算结果进行对比,结果表明二者符合良好.本文研究可为反应堆压力容器老化管理评估的计算分析工作提供重要参考.

  14. 一种降低OFDM信号PAPR的改进PTS方法%A kind of reducing PAPR of OFDM signal using improved PTS method.

    Institute of Scientific and Technical Information of China (English)

    曾庆芳; 何选森

    2012-01-01

    部分传输序列(PTS)方法通过选择合适的相位序列以降低信号峰值出现的概率,该方法不会使信号发生畸变.但是传统的PTS技术计算复杂度非常大,需遍历所有可选的相位因子,其计算量随分割子序列数按指数增长.提出了一种正倒二叉树多层相位序列方法,该方法通过对称的树形搜索,搜索出最优的相位序列.仿真结果表明,该方法大大降低系统的复杂度,同时PAPR得到更好的抑制.%By choosing the appropriate phase sequence, Partial Transmit Sequence(PTS) method reduces the probability of the signal peak, this method does not make the signal distortion. But conventional PTS technique has very large computational complexity, needs to traverse all the optional phase factor, its calculation sequence increases with the number of separate exponential growth. In this paper, a multi-phase sequence method is proposed, which is inverted binary tree. By symmetrical tree searching, this method searches out the optimal phase sequence. Simulation results show that the method reduces the system complexity, while the PAPR has been better suppressed.

  15. A New Method for the Detection and Enumeration of Xylitol-resistant (fructose-PTS-) Strains of Streptococcus mutans from Pure Cultures and Human Saliva

    OpenAIRE

    Dréan, M. -F.; Trahan, L.

    2011-01-01

    A simple procedure for the identification and enumeration, in large bacterial populations, of Streptococcus mutans of both xylitol-resistant and xylitol-sensitive phenotypes was developed. Since xylitol-resistant cells have lost the capacity to take up xylitol from the extracellular medium, due to a defect in their fructose-PTS, there is no uptake of [14C]xylitol by these cells whereas the [14C]xylitol taken up by the sensitive cells is used to visualise them by autoradiography. The method wa...

  16. 不同叠加训练序列PTS降低PAPR性能比较%Comparison of Different Superimposed Training Sequence PTS for PAPR Reduction

    Institute of Scientific and Technical Information of China (English)

    张杰; 罗仁泽; 党煜蒲; 牛娜; 李芮; 杨娇

    2014-01-01

    Partial Transmit Sequences ( PTS) is an efficient scheme for Peak-to-Average Power Ratio ( PAPR) reduction in Orthogonal Frequency Division Multiplexing ( OFDM) system,but the performance of reduction is limited and the sideband information occupied the spectrum resources. Based on the traditional PTS method and the method of superimposed training PTS,the performance of PAPR reduc-tion from the superposition of different training sequences and the different training sequences for phase rotation factors and power alloca-tion factor is analyzed. The simulation results show that the better autocorrelation superimposed training sequence has the better capacity of PAPR reduction,different training sequences for phase rotation factor has little effect on PAPR reduction,and when using Hadama code and the power allocation factor is greater than 0. 15,the ability of PAPR reduction is enhanced. In this scheme,the training sequences can not only use for synchronization and channel estimation,but also promote the band efficiency and PAPR reduction ability of the system.%部分传输序列(PTS)能有效降低正交频分复用(OFDM)系统的峰均功率比(PAPR),但是其存在降低性能有限和边带信息占用频谱资源的问题。文中在传统PTS方法的基础上,基于叠加训练序列PTS降低PAPR的方法,分析了叠加不同训练序列、不同训练序列作相位旋转因子及功率分配因子对降低PAPR性能的影响。仿真结果表明:叠加自相关性较好的训练序列,降低PAPR的能力更强;不同训练序列作相位旋转因子时,对降低PAPR的效果影响不大;采用Hadama码、功率分配因子大于0.15时,降低PAPR的能力增强。该方法中的训练序列,不仅可以用于同步﹑信道估计,而且可以降低PAPR,并提高系统频谱利用率。

  17. System Losses and Assessment Trade Study

    Energy Technology Data Exchange (ETDEWEB)

    David Shropshire; Steve Piet; Nick Soelberg; Robert Cherry; Roger Henry; David Meikrantz; Greg Teske; Eric Shaber; Candido Pereira

    2009-09-01

    This Advanced Fuel Cycle Initiative (AFCI) study has developed new analysis methods to examine old and new technology options toward the goal of improving fuel cycle systems. We have integrated participants and information from AFCI Systems Analysis, Transmutation Fuels, Separations, and Waste Form Campaigns in the Systems Losses and Assessment Trade Study. The initial objectives of this study were to 1) increase understanding of system interdependencies and thereby identify system trade-offs that may yield important insights, 2) define impacts of separations product purity on fuel manufacture and transmutation reactivity, 3) define impacts from transuranic (TRU) losses to waste, 4) identify the interrelationships involved in fuels and separations technology performance, and 5) identify system configuration adjustments with the greatest potential for influencing system losses. While bounding and analyzing this initial problem, we also identified significantly higher-level programmatic drivers with broad implications to the current fuel cycle research charter and the general issue of a DOE complex wide need for a comprehensive and integrated nuclear material management as addressed by the new DOE Order 410.2 titled “Management of Nuclear Materials”. The initial modeling effort developed in this study for a much smaller subset of material (i.e., commercial fuel) and a selected transmutation scheme (i.e., fast reactor recycling) is a necessary first step towards examining a broader set of nuclear material management options, dispositioning strategies and integrated waste management options including potential areas of research leverage. The primary outcome from this initial study has been an enhanced integration among Campaigns and associated insights and analysis methods. Opportunities for improved understanding between the groups abound. The above lanthanide-actinide example highlights the importance of evaluating options via integration across the Campaigns

  18. Field Test of ATHEANA (A Technique for Human Event Analysis) in Pressurised Thermal Shock Probabilistic Risk Assessments

    International Nuclear Information System (INIS)

    The U.S. Nuclear Regulatory Commission (USNRC) is currently developing the technical basis for potentially modifying the Pressurised Thermal Shock (PTS) screening criteria specified in Title 10 Part 50.61 of the U.S. Code of Federal Regulations. As part of this effort, PTS probabilistic risk assessments (PRAs) are being performed by the USNRC and its contractors, for two U.S. nuclear power plants, with assistance by the respective utilities. Two other plant analyses will also be performed as part of the PTS work, but are not the subject of this paper. These latter two analyses are being performed by industry and will be reviewed by the USNRC for inclusion into the entire effort. The ATHEANA methodology is being applied to address the human reliability portion of the two USNRC analyses in a way that is also significantly interactive with the accident sequence and system modelling portions of the work. This paper discusses the results to date of the application of ATHEANA in these PTS analyses, including consideration of possible relevant errors of commission. The field test of ATHEANA on this project has served two purposes. One is to use it in developing technical analyses to address and solve a particular issue; i.e., the risk of PTS. The results of these analyses will be used by the USNRC to decide whether or not the PTS screening criteria should be modified. The second purpose is to test the use of ATHEANA in a real application to determine strengths and weaknesses of the method, and how it might be improved. With regard to the first purpose, the PTS project is one where a current screening criteria may be relaxed. Before that can be done, the NRC must be sure that it is safe to do so, and to the extent the specific risk values affect that decision, those values must be able to withstand public scrutiny. Since the ATHEANA process requires the analysts to identify potential vulnerabilities and challenging scenario deviations associated with a human action, and to

  19. Formative peer assessment in a CSCL environment: A case study.

    NARCIS (Netherlands)

    Prins, Frans; Sluijsmans, Dominique; Kirschner, Paul A.; Strijbos, Jan Willem

    2007-01-01

    In this case study our aim was to gain more insight in the possibilities of qualitative formative peer assessment in a computer supported collaborative learning (CSCL) environment. An approach was chosen in which peer assessment was operationalized in assessment assignments and assessment tools that

  20. Research on structural integral assessment of cylinders with circumference cracks under pressurized thermal shock based on probabilistic fracture mechanics

    International Nuclear Information System (INIS)

    Background: Many investigations on the structural integrity assessment of reactor pressure vessel (RPV) under the pressure thermal stress (PTS) conditions have been performed. Probabilistic fracture mechanics (PFM) technique has been used for RPV PTS analysis since 1980. However, research on the structure integrity assessment techniques using the PFM method is insufficient in China to support the application of the method to be used for assessment of RPV under PTS conditions. Purpose: To gain the effective right assessment approach applied to Chinese RPV against PTS. Methods: Thermal stress distribution along the cylinder wall-thickness under PTS is firstly evaluated by FE in order to get the corresponding stress intensity factors (SIF) and to validate them with some available SIF solutions. The PFM analyses based on crack initiation are then performed under conditions of the crack size, fracture toughness and material yield stress. Both linear elastic fracture mechanics and R6 method are used in the analyses, and the sensitivity of uncertainties as well as the effect of the assessment method is discussed. Monte Carlo simulation is used to calculate the failure probability. Results: preliminary software is developed to perform the assessment for PTS analysis. The failure probability with R6 method is a little higher than with the linear elastic fracture mechanics approach. The effect of reference nil-ductility transition temperature RTNDT on the failure probability is more significant than other factors. Conclusions: Many uncertainties should be considered in RPV PTS analysis with PFM approach in the further, including the input parameters and failure models. Low RTNDT can extend the time of failure, and reduce the failure probability. (authors)

  1. Undergraduate study in psychology: Curriculum and assessment.

    Science.gov (United States)

    Norcross, John C; Hailstorks, Robin; Aiken, Leona S; Pfund, Rory A; Stamm, Karen E; Christidis, Peggy

    2016-01-01

    The undergraduate curriculum in psychology profoundly reflects and shapes the discipline. Yet, reliable information on the undergraduate psychology curriculum has been difficult to acquire due to insufficient research carried out on unrepresentative program samples with disparate methods. In 2014, APA launched the first systematic effort in a decade to gather national data on the psychology major and program outcomes. We surveyed a stratified random sample of department chairs/coordinators of accredited colleges and universities in the United States that offer undergraduate courses and programs in psychology. A total of 439 undergraduate psychology programs (45.2%) completed the survey. This article summarizes, for both associate and baccalaureate programs, the results of the Undergraduate Study in Psychology. Current practices concerning the introductory course, the courses offered, core requirements, the psychology minor, and tracks/concentrations are presented. The frequency of formal program reviews and program-level assessment methods are also addressed. By extending prior research on the undergraduate curriculum, we chronicle longitudinal changes in the psychology major over the past 20 years.

  2. Assessing English proficiency for university study

    CERN Document Server

    Read, John

    2015-01-01

    This book focuses on strategies and procedures for assessing the academic language ability of students entering an English-medium university, so that those with significant needs can have access to opportunities to enhance their language skills.

  3. 基于PTS缺陷型大肠杆菌构建莽草酸生产菌%Construction of shikimic acid-producing engineered Escherichia coli strains based on ptsHIcrr mutants

    Institute of Scientific and Technical Information of China (English)

    邹永康; 周军智; 孙旭; 蔡亚非; 戴红梅; 李树龙; 周长林; 方宏清

    2011-01-01

    对大肠杆菌芳香族氨基酸合成途径进行代谢流改造,以实现高效的生物制备莽草酸.以磷酸烯醇式丙酮酸-糖磷酸转移酶系统(PTS系统)敲除菌DH5αΔptsHIcrr(DHP)为基础,特异性敲除aroL,ydiB基因并转入受阿拉伯糖诱导表达的T7-RNA聚合酶基因,最终构建一系列产莽草酸宿主菌.再将aroE、aroB、tktA、glk、aroF组成的系列基因串联起来置于质粒上,在T7启动子控制下表达,经摇瓶培养检测得知,不同重组菌产莽草酸能力与对照相比均有明显提高,其中DHPYA-T7/pAOC-TGEFB菌株产量最高,可达到392 mg/L.为进一步构建高表达莽草酸工程菌奠定基础.%Metabolic engineering for aromatic amino acid biosynthesis pathway in Escherichia coli to acquire high-level biosynthesis of shikimic acid was reported. Knockout of aroL, ydiB genes and knock-in of T7-RNA-Polymerase gene which expression was controlled by L-arabinose based on the initial strain DH5α△ptsHlcrr (DHP), resulted in a series of shikimic acid-producing host strains. A series of tandem genes consisting of aroE, aroB, tktA, glk or aroFfbr were controlled by T7 promoter on plasmids were transformed into these host strains. According to the concentration of shikimic acid in shake-flask culture, all the engineered strains displayed high-potentiality compared to the control strain DHP, and the strain DHPYA-T7/pAOC-TGEFB synthesized the highest yield of 392 mg/L of shikimic acid. This study layed a strong foundation for constructing a high-level shikimic acid-producing engineered strain.

  4. The Present Absence: Assessment in Social Studies Classrooms

    Science.gov (United States)

    Torrez, Cheryl A.; Claunch-Lebsack, Elizabeth Ann

    2014-01-01

    In this article, first the authors describe the aims of and a definition of social studies education and classroom assessment. Second, the authors provide an overview of issues related to classroom assessment followed by trends in social studies classrooms and assessment. Then the authors address essential systems and best practices related to…

  5. Student Perceptions of Peer Assessment: An Interdisciplinary Study

    Science.gov (United States)

    Planas Lladó, Anna; Soley, Lídia Feliu; Fraguell Sansbelló, Rosa Maria; Pujolras, Gerard Arbat; Planella, Joan Pujol; Roura-Pascual, Núria; Suñol Martínez, Joan Josep; Moreno, Lino Montoro

    2014-01-01

    Peer assessment provides students with multiple benefits during their learning process. The aim of our study is to examine students' perception of peer assessment. Questionnaires were administered before and after the peer-assessment process to 416 students studying 11 different subjects in four different fields taught at the University of…

  6. Energy security assessment framework and three case-studies

    OpenAIRE

    CHERP, ALEH; Jewell, Jessica

    2013-01-01

    This chapter provides a novel framework for assessing energy security and illustrates its application by the Global Energy Assessment, the IEA Model for Short-term energy security and in several studies of long-term global energy security.

  7. Cooperative Student Assessment Method: an Evaluation Study

    Directory of Open Access Journals (Sweden)

    Antonella Grasso

    2006-06-01

    Full Text Available Training through the Internet poses a series of technical problems and pedagogical issues. Traditional training is not indiscriminate but takes on different forms according to the needs of the subject being trained and the context where such training occurs. In order to make the systems adaptable in this way, a model of the student’s characteristics - the student model - has to be set up, maintained and updated. However, there are many difficulties involved in obtaining sufficient information to create an accurate student model. One way to solve this problem is to involve students in the student modeling process, stimulating them to provide the necessary information by means of a dialog in which the student and system build the student model according to a collaborative process. The present work describes a cooperative student modeling method (Cooperative Student Assessment - CSA which builds a joint system-student assessment of student’s activities on the basis of the student’s self-assessment ability estimation and a prototype system for children, addressing the learning of fractions, in which CSA is implemented. The article also reports the result of an experimentation carried out with learners attending primary school aiming at evaluating the effectiveness of involving students in the assessment process by comparing two versions of the same system: one using cooperative student modeling and the other the traditional overlay model.

  8. Assessment Leaders' Perspectives of Institutional Cultures of Assessment: A Delphi Study

    Science.gov (United States)

    Fuller, Matthew; Henderson, Susan; Bustamante, Rebecca

    2015-01-01

    Institutional cultures of assessment are praised as beneficial to student learning. Yet, extant studies have not explored the theoretical foundations and pragmatic approaches to shaping cultures of assessment. The researchers used the Delphi method to explore 10 higher education assessment leaders' attitudes and theoretical perspectives regarding…

  9. Assessing biofuel crop invasiveness: a case study.

    Directory of Open Access Journals (Sweden)

    Christopher Evan Buddenhagen

    Full Text Available BACKGROUND: There is widespread interest in biofuel crops as a solution to the world's energy needs, particularly in light of concerns over greenhouse-gas emissions. Despite reservations about their adverse environmental impacts, no attempt has been made to quantify actual, relative or potential invasiveness of terrestrial biofuel crops at an appropriate regional or international scale, and their planting continues to be largely unregulated. METHODOLOGY/PRINCIPAL FINDINGS: Using a widely accepted weed risk assessment system, we analyzed a comprehensive list of regionally suitable biofuel crops to show that seventy percent have a high risk of becoming invasive versus one-quarter of non-biofuel plant species and are two to four times more likely to establish wild populations locally or be invasive in Hawaii or in other locations with a similar climate. CONCLUSIONS/SIGNIFICANCE: Because of climatic and ecological similarities, predictions of biofuel crop invasiveness in Hawaii are applicable to other vulnerable island and subtropical ecosystems worldwide. We demonstrate the utility of an accessible and scientifically proven risk assessment protocol that allows users to predict if introduced species will become invasive in their region of interest. Other evidence supports the contention that propagule pressure created by extensive plantings will exacerbate invasions, a scenario expected with large-scale biofuel crop cultivation. Proactive measures, such as risk assessments, should be employed to predict invasion risks, which could then be mitigated via implementation of appropriate planting policies and adoption of the "polluter-pays" principle.

  10. Clinical experimental stress studies: methods and assessment.

    Science.gov (United States)

    Bali, Anjana; Jaggi, Amteshwar Singh

    2015-01-01

    Stress is a state of threatened homeostasis during which a variety of adaptive processes are activated to produce physiological and behavioral changes. Stress induction methods are pivotal for understanding these physiological or pathophysiological changes in the body in response to stress. Furthermore, these methods are also important for the development of novel pharmacological agents for stress management. The well-described methods to induce stress in humans include the cold pressor test, Trier Social Stress Test, Montreal Imaging Stress Task, Maastricht Acute Stress Test, CO2 challenge test, Stroop test, Paced Auditory Serial Addition Task, noise stress, and Mannheim Multicomponent Stress Test. Stress assessment in humans is done by measuring biochemical markers such as cortisol, cortisol awakening response, dexamethasone suppression test, salivary α-amylase, plasma/urinary norepinephrine, norepinephrine spillover rate, and interleukins. Physiological and behavioral changes such as galvanic skin response, heart rate variability, pupil size, and muscle and/or skin sympathetic nerve activity (microneurography) and cardiovascular parameters such as heart rate, blood pressure, and self-reported anxiety are also monitored to assess stress response. This present review describes these commonly employed methods to induce stress in humans along with stress assessment methods. PMID:26020552

  11. Wound assessment tools and nurses’ needs: an evaluation study

    OpenAIRE

    Greatrex-White, Sheila; Moxey, Helen

    2013-01-01

    The purpose of this study was to ascertain how well different wound assessment tools meet the needs of nurses in carrying out general wound assessment and whether current tools are fit for purpose. The methodology employed was evaluation research. In order to conduct the evaluation, a literature review was undertaken to identify the criteria of an optimal wound assessment tool which would meet nurses’ needs. Several freely available wound assessment tools were selected based on predetermin...

  12. Formative peer assessment in a CSCL Environment: A case study

    OpenAIRE

    Prins, F.J.; Sluijsmans, D.M.A.; Kirschner, P.A.; Strijbos, J.-W.

    2005-01-01

    In this case study our aim was to gain more insight in the possibilities of qualitative formative peer assessment in a computer supported collaborative learning (CSCL) environment. An approach was chosen in which peer assessment was operationalized in assessment assignments and assessment tools that were embedded in the course material. The course concerned a higher education case-based virtual seminar, in which students were asked to conduct research and write a report in small multidiscipli...

  13. Potential impact of enhanced fracture-toughness data on fracture mechanics assessment of PWR vessel integrity for pressurized thermal shock

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, T.L.; Theiss, T.J.

    1991-01-01

    The Heavy Section Steel Technology (HSST) Program is involved with the generation of enhanced fracture-initiation toughness and fracture-arrest toughness data of prototypic nuclear reactor vessel steels. These two sets of data are enhanced because they have distinguishing characteristics that could potentially impact PWR pressure vessel integrity assessments for the pressurized-thermal shock (PTS) loading condition which is a major plant-life extension issue to be confronted in the 1990's. A series of large-scale fracture-mechanics experiments have produced crack-arrest (K{sub Ia}) data with the distinguishing characteristic that the values are considerably above 220 MPA {center dot} {radical}m. The implicit limit of the ASME Code and the limit used in the Integrated Pressurized Thermal Shock (IPTS) studies. Currently, the HSST Program is planning experiments to verify and quantify for A533B steel the distinguishing characteristic of elevated the distinguishing characteristic of elevated initiation-fracture toughness for shallow flaws which has been observed for other steels. The results of the analyses indicated that application of the enhanced K{sub Ia} data does reduce the conditional probability of failure P(F{vert bar}E); however, it does not appear to have the potential to significantly impact the results of PTS analyses. The application of enhanced fracture-initiation-toughness data for shallow flaws also reduces P(F{vert bar}E), and does appear to have a potential for significantly affecting the results of PTS analyses. 19 refs., 11 figs., 1 tab.

  14. A study of reactor vessel integrity assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Hoon [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of); Kim, Jong Kyung; Shin, Chang Ho; Seo, Bo Kyun [Hanyang Univ., Seoul (Korea, Republic of)

    1999-02-15

    The fast neutron fluence at the Reactor Pressure Vessel(RPV) of KNGR designed for 60 years lifetime was calculated by full-scope Monte Carlo simulation for reactor vessel integrity assessment. KNGR core geometry was modeled on a three-dimensional representation of the one-sixteenth of the reactor in-vessel component. Each fuel assemblies were modeled explicitly, and each fuel pins were axially divided into 5 segments. The maximum flux of 4.3 x 10{sup 10} neutrons/cm{sup 2}. sec at the RPV was obtained by tallying neutrons crossing the beltline of inner surface of the RPV.

  15. 降低OFDM系统中PAPR的次优化PTS算法%PAPR Reduction of OFDM System by Sub-Optimal PTS Algorithm

    Institute of Scientific and Technical Information of China (English)

    鲁锦锋; 文武

    2008-01-01

    正交频分复用(OFDM)系统的主要缺点是峰均功率比(PAPR)增大会严重地降低了发射机中高功率放大器(HPA)的效率.部分传输序列(PTS)算法能有效地降低OFDM信号的PAPR概率,但随着PTS中分割子块的增多也带来了高的计算复杂度.为此,文中提出一种新的PTS算法,该算法比传统的穷尽搜寻法具有更佳的性能.仿真结果表明,文中所提PTS算法在降低PAPR相似的情况下,具有更小的计算复杂度.

  16. CHASE assessment of the North Sea – a pilot study

    DEFF Research Database (Denmark)

    Green, N.; Andersen, Jesper; Høgåsen, T.;

    In this pilot study, hazardous substances in the North Sea were assessed and classified using the HELCOM Chemical Substances Status Assessment Tool (CHASE). The study was based on monitoring by Belgium, Denmark, France, Germany, the Netherlands, Norway, Sweden and the United Kingdom. Together, 1350...

  17. Quality Assessment of Internationalised Studies: Theory and Practice

    Science.gov (United States)

    Juknyte-Petreikiene, Inga

    2013-01-01

    The article reviews forms of higher education internationalisation at an institutional level. The relevance of theoretical background of internationalised study quality assessment is highlighted and definitions of internationalised studies quality are presented. Existing methods of assessment of higher education internationalisation are criticised…

  18. Cumulative assessment : Strategic choices to influence students' study effort

    NARCIS (Netherlands)

    Kerdijk, Wouter; Tio, Rene A.; Mulder, B. Florentine; Cohen-Schotanus, Janke

    2013-01-01

    Background: It has been asserted that assessment can and should be used to drive students' learning. In the current study, we present a cumulative assessment program in which test planning, repeated testing and compensation are combined in order to influence study effort. The program is aimed at hel

  19. Wound assessment tools and nurses' needs: an evaluation study.

    Science.gov (United States)

    Greatrex-White, Sheila; Moxey, Helen

    2015-06-01

    The purpose of this study was to ascertain how well different wound assessment tools meet the needs of nurses in carrying out general wound assessment and whether current tools are fit for purpose. The methodology employed was evaluation research. In order to conduct the evaluation, a literature review was undertaken to identify the criteria of an optimal wound assessment tool which would meet nurses' needs. Several freely available wound assessment tools were selected based on predetermined inclusion and exclusion criteria and an audit tool was developed to evaluate the selected tools based on how well they met the criteria of the optimal wound assessment tool. The results provide a measure of how well the selected wound assessment tools meet the criteria of the optimal wound assessment tool. No tool was identified which fulfilled all the criteria, but two (the Applied Wound Management tool and the National Wound Assessment Form) met the most criteria of the optimal tool and were therefore considered to best meet nurses' needs in wound assessment. The study provides a mechanism for the appraisal of wound assessment tools using a set of optimal criteria which could aid practitioners in their search for the best wound assessment tool.

  20. Methodologic assessment of radiation epidemiology studies

    International Nuclear Information System (INIS)

    Epidemiologic studies of the late effects of ionizing radiation have utilized the entire spectrum of situations in which man has been exposed. These studies have provided insights into the dependence of human effects upon not only dose to target tissues but also other dimensions of exposure, host characteristics, and time following exposure. Over the past three decades studies have progressed from the mere identification of effects to their measurement. Because investigators of human effects have no control over the exposure situation, validity must be sought in the consistency of findings among independent studies and with accepted biologic principles. Because exposure may be confounded with factors that are hidden from view, bias may enter into any study of human exposure. Avoidance of bias and attainment of sufficient power to detect relationships that are real are methodologic challenges. Many methodologic issues, e.g., those associated with the definition and measurement of specific end-points, or with the selection of appropriate controls, permeate epidemiologic work in all fields. Others, especially those concerned with the measurement of exposure, the patterning of events in time after exposure, and the prediction of events beyond the scope of existing observations give radiation epidemiology its distinctive character

  1. Preliminary Systems Design Study assessment report

    International Nuclear Information System (INIS)

    The System Design Study (SDS), part of the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex's Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each concept. This volume of the Systems Design Study contain four Appendixes that were part of the study. Appendix A is an EG ampersand G Idaho, Inc., report that represents a review and compilation of previous reports describing the wastes and quantities disposed in the Subsurface Disposal Area of the Idaho National Engineering Laboratory. Appendix B contains the process flowsheets considered in this study, but not selected for detailed analysis. Appendix C is a historical tabulation of radioactive waste incinerators. Appendix D lists Department of Energy facilities where cementation stabilization systems have been used

  2. Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study

    Directory of Open Access Journals (Sweden)

    Riess Hanno

    2010-03-01

    Full Text Available Abstract Background Cachexia is a common problem in patients (pts suffering from upper gastrointestinal cancer. In addition, most of these patients suffer from malabsorption and stenosis of the gastrointestinal tract due to their illness. Various methods of supplementary nutrition (enteral, parenteral are practised. In patients with advanced pancreatic cancer (APC, phase angle, determined by bio-electrical impedance analysis (BIA, seems to be a survival predictor. The positive influence of BIA determinate predictors by additional nutrition is currently under discussion. Methods To examine the impact of additional parenteral nutrition (APN we assessed outpatients suffering from APC and progressive cachexia. The assessment based on the BIA method. Assessment parameters were phase angle, ECM/BCM index (ratio of extracellular mass to body cell mass, and BMI (body mass index. Patients suffering from progressive weight loss in spite of additional enteral nutritional support were eligible for the study. Results Median treatment duration in 32 pts was 18 [8-35] weeks. Response evaluation showed a benefit in 27 pts (84% in at least one parameter. 14 pts (43.7% improved or stabilised in all three parameters. The median ECM/BCM index was 1.7 [1.11-3.14] at start of APN and improved down to 1.5 [1.12-3.36] during therapy. The median BMI increased from 19.7 [14.4-25.9] to 20.5 [15.4-25.0]. The median phase angle improved by 10% from 3.6 [2.3-5.1] to 3.9 [2.2-5.1]. Conclusions We demonstrated the positive impact of APN on the assessed parameters, first of all the phase angle, and we observed at least a temporary benefit or stabilisation of the nutritional status in the majority of the investigated patients. Based on these findings we are currently investigating the impact of APN on survival in a larger patient cohort. Trial registration ClinicalTrials.gov Identifier: NCT00919659

  3. Risk Assessment Stability: A Revalidation Study of the Arizona Risk/Needs Assessment Instrument

    Science.gov (United States)

    Schwalbe, Craig S.

    2009-01-01

    The actuarial method is the gold standard for risk assessment in child welfare, juvenile justice, and criminal justice. It produces risk classifications that are highly predictive and that may be robust to sampling error. This article reports a revalidation study of the Arizona Risk/Needs Assessment instrument, an actuarial instrument for juvenile…

  4. Quality of assessments within reach: Review study of research and results of the quality of assessments

    NARCIS (Netherlands)

    Maassen, N.A.M.; Otter, den D.; Wools, S.; Hemker, B.T.; Straetmans, G.J.J.M.; Eggen, T.J.H.M.

    2015-01-01

    Educational tests and assessments are important instruments to measure a student’s knowledge and skills. The question that is addressed in this review study is: “which aspects are currently considered as important to the quality of educational assessments?” Furthermore, it is explored how this infor

  5. Assessment of Correspondent Banks Case Study

    Directory of Open Access Journals (Sweden)

    Abeer F.A.A. Abbadi

    2011-01-01

    Full Text Available Problem statement: This study aims at evaluating corresponding banks in Jordan. Characterizing the goals, instruments and profitability under unfavorable conditions of financial setbacks and unfair competition among banks. Focuses on the feasibility and profitability of Philadelphia Investment Bank in its international trade via its Correspondent banks. Approach: Problems and setbacks shall be screened out; reasoned and appropriate optimal recommendations are to be presented. Results: The study followed the analytical approach and depended on “History Documents” and “In depth Interview” techniques and puts a major emphasis on the fact that correspondent banking has become an essential cornerstone of international business amid the new era of world trade, globalization, external competition and cartels from the major opponents to Jordanian Banks, the main conclusion is realized the importance of correspondent banks in the international trade, so Philadelphia bank benefited from correspondent banks for the cheap cost of market entry and services were tailored to the scale of required locale. But there was no big investment in staff facilities. And there are setbacks in dealing with correspondent banks, such as fund delay in reaching destinations on time. Moreover, Jordanian banks have suffered in general from these correspondent banks because they deal with these correspondent banks individually. Conclusion/Recommendations: The recommendation of the study is, it is the time to consider solidification and forming one financial block, or a sort of cartel and face these correspondent banks in one unit. They are also called for developing collective strategies. Small banks should merge and form huge capital blocks. Another strategy is that Jordanian banks should minimize the reliance on foreign banks and should develop their own, by establishing international branches abroad to help financing their international activities.

  6. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne

    2009-12-01

    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second

  7. Preliminary Systems Design Study assessment report

    International Nuclear Information System (INIS)

    The System Design Study (SDS), part of the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex's Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each concept

  8. Preliminary systems design study assessment report

    International Nuclear Information System (INIS)

    The System Design Study (SDS), part of the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex's Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each concept

  9. Are failures of anterior cruciate ligament reconstruction associated with steep posterior tibial slopes? A case control study

    Institute of Scientific and Technical Information of China (English)

    Li Yue; Hong Lei; Feng Hua; Wang Qianqian; Zhang Hui; Song Guanyang

    2014-01-01

    Background Recently,increasing number of literature has identified the posterior tibial slope (PTS) as one of the risk factors of primary anterior cruciate ligament (ACL) injury.However,few studies conceming the association between failure of ACL reconstruction (ACLR) and PTS have been published.The objective of this study was to explore the association between the failure of ACLR and PTS at a minimum of two years follow-up.Methods Two hundred and thirty eight eligible patients from June 2009 to October 2010 were identified from our database.A total of 20 failure cases of ACLR and 20 randomly selected controls were included in this retrospective study.The demographic data and the results of manual maximum side-to-side difference with KT-1000 arthrometer at 30° of knee flexion and pivot-shift test before the ACLR and at the final follow-up were collected.The medial and lateral PTSs were measured using the magnetic resonance imaging (MRI) scan,based on Hudek's measurement.A comparison of PTS between the two groups was performed.Results The overall failure rate of the present study was 8.4%.Of the 40 participants,the mean medial PTS was 4.1°±3.2° and the mean lateral PTS was 4.6°±2.6°.The medial PTS of the ACLR failure group was significantly steeper than the control group (3.5°±2.5° vs.6.1°±2.1°,P=0.000).Similarly,the lateral PTS of the ACLR failure group was significantly steeper than the control group (2.9°±2.1 ° vs.5.5°±3.0°,P=0.006).For medial PTS ≥5°,the odds ratio of ACLR failure was 6.8 (P=0.007); for lateral PTS ≥5°,the odds ratio of ACLR failure was 10.8 (P=0.000).Conclusion Both medial and lateral PTS were significantly steeper in failures of ACLR than the control group.Medial or lateral PTS ≥5° was a new risk factor of ACLR failure.

  10. Dropout and Violence Needs Assessment: A Follow-up Study

    Science.gov (United States)

    Miltich, Aimee P.; Hunt, Mary Helen; Meyers, Joel

    2004-01-01

    The current study investigated a needs assessment survey designed to measure perceptions of causes of dropout and school violence and related interventions. The needs assessment was conceptualized as a first step to be taken by schools to facilitate program planning, school-based implementation and acceptability of programs designed to prevent…

  11. Higher Education Quality Assessment in China: An Impact Study

    Science.gov (United States)

    Liu, Shuiyun

    2015-01-01

    This research analyses an external higher education quality assessment scheme in China, namely, the Quality Assessment of Undergraduate Education (QAUE) scheme. Case studies were conducted in three Chinese universities with different statuses. Analysis shows that the evaluated institutions responded to the external requirements of the QAUE…

  12. Three Reflections on Assessing Safety Training Needs: A Case Study

    Science.gov (United States)

    Sleezer, Catherine M.; Kelsey, Kathleen D.; Wood, Thomas E.

    2008-01-01

    Needs assessment plays an important role in training and human performance improvement efforts, but the literature contains little research on this topic. This study extended previous research on the Performance Analysis for Training (PAT) model of needs assessment by examining its implementation to determine environmental and occupational health…

  13. Unmasking Cleckley's psychopath: assessing historical case studies.

    Science.gov (United States)

    DeShong, Hilary L; Helle, Ashley C; Mullins-Sweatt, Stephanie N

    2016-05-01

    The current study investigated original case descriptions of psychopathy (Cleckley, 1941) in relation to current conceptualizations and general personality traits. Attorneys, forensic psychologists and clinical faculty members completed ratings of psychopathy and personality after reading vignettes based on Cleckley's descriptions of a psychopath. The results suggest that professionals' ratings are consistent with current conceptualizations of psychopathy. Furthermore, the five-factor model (FFM) personality traits of the vignettes aligned with the current literature on the FFM and psychopathy (i.e. low neuroticism, conscientiousness and agreeableness). The results further supported that a general trait model, like the FFM, may be well suited to describe the underlying personality traits of psychopathy. Gender differences were also examined. PMID:26931520

  14. Preliminary systems design study assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Mayberry, J.L.; Feizollahi, F.; Del Signore, J.C.

    1991-10-01

    The System Design Study (SDS), part of the Waste Technology Development Department of the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex's Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each concept. The SDS results are published in eight volumes. Volume I contains an executive summary. The SDS summary and analysis of results are presented in Volume II. Volumes III through VII contain descriptions of twelve system and four subsystem concepts. Volume VIII contains the appendixes.

  15. Dynamic assessment versus static assessment: A study of reading comprehension ability in Iranian EFL learners

    OpenAIRE

    Nazari, Behzad; Mansouri, Saeed

    2014-01-01

    This study extends traditional or static assessment of reading comprehension in foreign language contexts and applies dynamic assessment (DA) to the development of learners’ reading ability. To homogenize the research population (N= 250), an Oxford Placement Test (OPT) was administered. On the basis of the test results, the population was sorted into three groups of reading-low, reading-mid, and reading-high students. The participants of this study were a sample of 30 participants with the lo...

  16. Assessing dance: A phenomonological study of formative assessment in dance education

    Directory of Open Access Journals (Sweden)

    Ninnie Andersson

    2014-07-01

    Full Text Available This article includes a study that examines how formative assessment in dance education is constituted in three Swedish upper secondary schools. The starting-point for the study is life-world phenomenology.  A phenomenological way of thinking entails that the human being is intersubjective, linked with and within the world and that learning requires the bodily subject´s active experience. To turn towards the things themselves and to be open and adherent to things in the world is a basic rule and the starting point for research within phenomenology. This study is based on empirical material from observations of the phenomenon formative assessment in dance. Spiegelberg´s philosophical method was used as a base for phenomenological analysis. The analysis results in three themes: modes of communication, dance-related knowledge and function of formative assessment. Formative assessment was observed in the study to commonly involve teachers´ verbal communication and visualisation. The assessment practice is a continuous activity and very rarely involves any kind of self-assessment or tests. The results were discussed and related to a life-world phenomenological view of learning and earlier research.

  17. Assessing the first wave of epidemiological studies of nanomaterial workers

    International Nuclear Information System (INIS)

    The results of early animal studies of engineered nanomaterials (ENMs) and air pollution epidemiology suggest that it is important to assess the health of ENM workers. Initial epidemiological studies of workers’ exposure to ENMs (<100 nm) are reviewed and characterized for their study designs, findings, and limitations. Of the 15 studies, 11 were cross-sectional, 4 were longitudinal (1 was both cross-sectional and longitudinal in design), and 1 was a descriptive pilot study. Generally, the studies used biologic markers as the dependent variables. All 11 cross-sectional studies showed a positive relationship between various biomarkers and ENM exposures. Three of the four longitudinal studies showed a negative relationship; the fourth showed positive findings after a 1-year follow-up. Each study considered exposure to ENMs as the independent variable. Exposure was assessed by mass concentration in 10 studies and by particle count in six studies. Six of them assessed both mass and particle concentrations. Some of the studies had limited exposure data because of inadequate exposure assessment. Generally, exposure levels were not very high in comparison to those in human inhalation chamber studies, but there were some exceptions. Most studies involved a small sample size, from 2 to 258 exposed workers. These studies represent the first wave of epidemiological studies of ENM workers. They are limited by small numbers of participants, inconsistent (and in some cases inadequate) exposure assessments, generally low exposures, and short intervals between exposure and effect. Still, these studies are a foundation for future work; they provide insight into where ENM workers are experiencing potentially adverse effects that might be related to ENM exposures

  18. Assessing the first wave of epidemiological studies of nanomaterial workers

    Energy Technology Data Exchange (ETDEWEB)

    Liou, Saou-Hsing, E-mail: shliou@nhri.org.tw [National Health Research Institutes, National Institute of Environmental Health Sciences (China); Tsai, Candace S. J. [Colorado State University, Department of Environmental and Radiological Health Science (United States); Pelclova, Daniela [Charles University in Prague, Department of Occupational Medicine, First Faculty of Medicine (Czech Republic); Schubauer-Berigan, Mary K.; Schulte, Paul A. [National Institute for Occupational Safety and Health (United States)

    2015-10-15

    The results of early animal studies of engineered nanomaterials (ENMs) and air pollution epidemiology suggest that it is important to assess the health of ENM workers. Initial epidemiological studies of workers’ exposure to ENMs (<100 nm) are reviewed and characterized for their study designs, findings, and limitations. Of the 15 studies, 11 were cross-sectional, 4 were longitudinal (1 was both cross-sectional and longitudinal in design), and 1 was a descriptive pilot study. Generally, the studies used biologic markers as the dependent variables. All 11 cross-sectional studies showed a positive relationship between various biomarkers and ENM exposures. Three of the four longitudinal studies showed a negative relationship; the fourth showed positive findings after a 1-year follow-up. Each study considered exposure to ENMs as the independent variable. Exposure was assessed by mass concentration in 10 studies and by particle count in six studies. Six of them assessed both mass and particle concentrations. Some of the studies had limited exposure data because of inadequate exposure assessment. Generally, exposure levels were not very high in comparison to those in human inhalation chamber studies, but there were some exceptions. Most studies involved a small sample size, from 2 to 258 exposed workers. These studies represent the first wave of epidemiological studies of ENM workers. They are limited by small numbers of participants, inconsistent (and in some cases inadequate) exposure assessments, generally low exposures, and short intervals between exposure and effect. Still, these studies are a foundation for future work; they provide insight into where ENM workers are experiencing potentially adverse effects that might be related to ENM exposures.

  19. Theoretical study on safety assessment indexes system of coal mines

    Institute of Scientific and Technical Information of China (English)

    SHI Shi-liang(施式亮); LI Run-qiu(李润求); XIE Jian-xiang(谢建湘)

    2003-01-01

    The safety status of the coal mines is closely correlated with the operating status and its changes of the whole working system in the coal mines, and the safety system is the sub-system of the whole production system. In this paper, based on the analysis of the complicacy of the safety sub-system and its affecting factors, the theory basis of the indexes system of the safety assessment was studied, including the establishing principles of the indexes system , the structure of the indexes system, the determining methods of the assessment indexes. The complete indexes system was established for the safety assessment of the coal mines in the paper.

  20. Exposure Assessment in the National Children’s Study: Introduction

    OpenAIRE

    Needham, Larry L.; Özkaynak, Halûk; Whyatt, Robin M.; Barr, Dana B.; Wang, Richard Y.; Naeher, Luke; Akland, Gerry; Bahadori, Tina; Bradman, Asa; Fortmann, Roy; Liu, L-J Sally; Morandi, Maria; O’Rourke, Mary Kay; Thomas, Kent; Quackenboss, James

    2005-01-01

    The science of exposure assessment is relatively new and evolving rapidly with the advancement of sophisticated methods for specific measurements at the picogram per gram level or lower in a variety of environmental and biologic matrices. Without this measurement capability, environmental health studies rely on questionnaires or other indirect means as the primary method to assess individual exposures. Although we use indirect methods, they are seldom used as stand-alone tools. Analyses of en...

  1. Using Event Studies to Assess the Impact of Unexpected Events

    OpenAIRE

    James V Koch; Robert N Fenili

    2013-01-01

    The quantitative assessment of the financial impact of unexpected events is the realm of the “event study.” We examine how CEOs, boards, and public policymakers can utilize event studies to inform and improve their decision making. The breadth of application of event studies is surprisingly broad and ranges from situations involving the death of a CEO to emergency product recalls. We present illustrative event studies for two Steve Jobs-related announcements concerning his health in order to ...

  2. Assessment

    Institute of Scientific and Technical Information of China (English)

    Geoff Brindley

    2005-01-01

    @@ Introduction TERMINOLOGY AND KEY CONCEPTS The term assessment refers to a variety of ways of collecting information on a learner's language ability or achievement. Although testing and assessment are often used interchangeably, the latter is an umbrella term encompassing measurement instruments administered on a ‘one-off’ basis such as tests, as well as qualitative methods of monitoring and recording student learning such as observation, simulations of project work. Assessment is also distinguished from evaluation which is concerned with the overall language programme and not just with what individual students have learnt. Proficiency assessment refers to the assessment of general language abilities acquired by the learner independent of a course of study.This kind of assessment is often done through the administration of standardised commercial language-proficency tests. On the other hand, assessment of achievement aims to establish what a student had learned in relation to a particular course or curriculum (thus frequently carried out by the teacher) .Achievement assesssment may be based either on the specific content of the course or on the course objectives (Hughes 1989).

  3. An action research study of secondary science assessment praxes

    Science.gov (United States)

    Ryan, Thomas Gerald

    This practical participatory action research study illuminates the assessment praxes of four Ontario secondary level science teachers at one school using a facilitative approach. Participants were joined by a thematic concern, that is, a commitment to inform and improve assessment. Hence, two distinct sets of research questions emerged. The first involves the nature of assessment as we asked, what was the current state of assessment practice in secondary science? What were participants' initial understandings of assessment and actual practices at the onset of this research? To what extent did these initial understandings and actual practices change due to the illumination of assessment praxes through action research involvement? What was their level of awareness of current Ontario government pronouncements and in what ways did they implement this knowledge? The second theme, concerning the nature of action research, was realised by asking what did participants learn about action research? What other learning and professional gains were realised during this study? And, what did I learn about action research and assessment through my involvement in this study? Data were collected via supportive discussion groups, individual interviews, classroom visitations, journals and documentation. This professional development experience facilitated 'interactive professionalism' as teachers worked in a small group and interacted frequently in the course of planning, testing new ideas, attempting to solve different problems, and assess the effectiveness of those ideas. In addition, this action research effort was strategic and systematic, to attain a high degree of specific interactions, (personal interviews, group meetings, classroom observations, evidence collection). This series of deliberate and planned intentions helped participants solve assessment dilemmas. We developed an awareness and understanding of the need for more preservice and inservice assessment training

  4. A physiotherapy triage assessment service for people with low back disorders: evaluation of short-term outcomes

    Directory of Open Access Journals (Sweden)

    Bath B

    2012-06-01

    Full Text Available Brenna Bath, Punam PahwaCollege of Medicine, University of Saskatchewan, Saskatoon, CanadaPurpose: To determine the short-term effects of physiotherapy triage assessments on self-reported pain, functioning, and general well-being and quality of life in people with low back-related disorders.Methods: Participants with low back–related complaints were recruited from those referred to a spinal triage assessment program delivered by physiotherapists (PTs. Before undergoing the triage assessment, the participants completed a battery of questionnaires covering a range of sociodemographic, clinical, and psychosocial features. The study used the Numeric Pain Rating Scale (NPRS, the Oswestry Disability Index (ODI, and the Medical Outcomes Survey 36-item short-form version 2 (SF-36v2 to assess self-reported pain, function, and quality of life. Baseline measures and variables were analyzed using a descriptive analysis method (ie, proportions, means, medians. Paired samples t-tests or Wilcoxon matched-pair signed-rank tests were used to analyze the overall group differences between the pretest and posttest outcome measures where appropriate.Results: A total of 108 out of 115 (93.9% participants completed the posttest survey. The Physical Component Summary of the SF36v2 was the only measure that demonstrated significant improvement (P < 0.001.Conclusion: A spinal triage assessment program delivered by PTs can be viewed as a complex intervention that may have the potential to affect a wide range of patient-related outcomes. Further research is needed to examine the long-term outcomes and explore potential mechanisms of improvement using a biopsychosocial framework.Keywords: interprofessional practice, quality of life, back pain, orthopedics

  5. Comprehensive Adult Student Assessment Systems Braille Reading Assessment: An Exploratory Study

    Science.gov (United States)

    Posey, Virginia K.; Henderson, Barbara W.

    2012-01-01

    Introduction: This exploratory study determined whether transcribing selected test items on an adult life and work skills reading test into braille could maintain the same approximate scale-score range and maintain fitness within the item response theory model as used by the Comprehensive Adult Student Assessment Systems (CASAS) for developing…

  6. Teaching, Learning, and Assessment Together: Reflective Assessments for Middle and High School English and Social Studies

    Science.gov (United States)

    Ellis, Arthur K.; Evans, Laurynn

    2010-01-01

    This book offers easy-to-use classroom strategies for middle and high school English and Social Studies classrooms. They demonstrate how teaching, learning, and assessment are inseparable and seamless. Each strategy will engage your students in activity and reflection, consuming little class time, costing nothing, and uniting the three dimensions…

  7. A kind of the PAPR of OFDM system using improved PTS method%一种OFDM系统峰均比的改良PTS算法

    Institute of Scientific and Technical Information of China (English)

    李欣; 胡晓天; 管绍军; 孙继明

    2012-01-01

    Partial Transmit Sequence (PTS) method by choosing the appropriate phase sequence to reduce the probability of the Signal peak, this method does not make the signal distortion. But conventional PTS technique is very large computational complexity, needing to traverse all the optional phase factor, its calculation sequence as the number of separate exponential growth. In this paper, proposing a multi-phase sequence is inverted binary tree method, this method by symmetrical tree searching, searching out the optimal phase sequence. Simulating results show that the method reduces the system complexity, while better suppress the PAPR.%部分传输序列(PTS)方法通过选择合适的相位序列以降低信号峰值出现的概率,该方法不会使信号发生畸变。但是传统的PTS技术计算复杂度非常大,需遍历所有可选的相位因子,其计算量随分割子序列数按指数增长。本文提出了一种正倒二叉树多层相位序列方法,该方法通过对称的树形搜索,搜索出最优的相位序列。仿真结果表明,该方法大大降低系统的复杂度.同时PAPR得到更好地抑制。

  8. RpoS synthesis is growth rate regulated in Salmonella typhimurium, but its turnover is not dependent on acetyl phosphate synthesis or PTS function.

    Science.gov (United States)

    Cunning, C; Elliott, T

    1999-08-01

    The RpoS sigma factor of enteric bacteria is either required for or augments the expression of a number of genes that are induced during nutrient limitation, growth into stationary phase, or in response to stresses, including high osmolarity. RpoS is regulated at multiple levels, including posttranscriptional control of its synthesis, protein turnover, and mechanisms that affect its activity directly. Here, the control of RpoS stability was investigated in Salmonella typhimurium by the isolation of a number of mutants specifically defective in RpoS turnover. These included 20 mutants defective in mviA, the ortholog of Escherichia coli rssB/sprE, and 13 mutants defective in either clpP or clpX which encode the protease active on RpoS. An hns mutant was also defective in RpoS turnover, thus confirming that S. typhimurium and E. coli have identical genetic requirements for this process. Some current models predict the existence of a kinase to phosphorylate the response regulator MviA, but no mutants affecting a kinase were recovered. An mviA mutant carrying the D58N substitution altering the predicted phosphorylation site is substantially defective, suggesting that phosphorylation of MviA on D58 is important for its function. No evidence was obtained to support models in which acetyl phosphate or the PTS system contributes to MviA phosphorylation. However, we did find a significant (fivefold) elevation of RpoS during exponential growth on acetate as the carbon and energy source. This behavior is due to growth rate-dependent regulation which increases RpoS synthesis at slower growth rates. Growth rate regulation operates at the level of RpoS synthesis and is mainly posttranscriptional but, surprisingly, is independent of hfq function. PMID:10438755

  9. Regional issue identification and assessment: study methodology. First annual report

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    The overall assessment methodologies and models utilized for the first project under the Regional Issue Identification and Assessment (RIIA) program are described. Detailed descriptions are given of the methodologies used by lead laboratories for the quantification of the impacts of an energy scenario on one or more media (e.g., air, water, land, human and ecology), and by all laboratories to assess the regional impacts on all media. The research and assessments reflected in this document were performed by the following national laboratories: Argonne National Laboratory; Brookhaven National Laboratory; Lawrence Berkeley Laboratory; Los Alamos Scientific Laboratory; Oak Ridge National Laboratory; and Pacific Northwest Laboratory. This report contains five chapters. Chapter 1 briefly describes the overall study methodology and introduces the technical participants. Chapter 2 is a summary of the energy policy scenario selected for the RIIA I study and Chapter 3 describes how this scenario was translated into a county-level siting pattern of energy development. The fourth chapter is a detailed description of the individual methodologies used to quantify the environmental and socioeconomic impacts of the scenario while Chapter 5 describes how these impacts were translated into comprehensive regional assessments for each Federal Region.

  10. Juvenile idiopathic arthritis outcome and prognosis according to catamnesis evaluation

    Directory of Open Access Journals (Sweden)

    O V Semenova

    2005-01-01

    Full Text Available Objective. To study outcome and prognosis in pts with juvenile idiopathic arthritis (JIA. Material and methods. 239 JIA pts with disease duration of 10 years and more were analyzed. 80 children and adolescents before 18 years old (66 girls and 14 boys were included in group 1. Arthritis clinical and laboratory activity, radiological stage and functional status according to Steinbroker and CHAQ questionnaire were assessed. 159 grown up pts (109 female and 50 male suffering from JIA from childhood were included in group 2. They were examined using Stanford Health Assessment Questionnaire (HAQ and a specially developed social status questionnaire. Results. Half pts of group 1 had recurrence of the disease during examination but activity in most cases did not exceed stage I or 2 (54% and 31% respectively. Joint destructive changes were revealed in 50% of pts. 80% of pts had radiological signs of secondary osteoarthritis. Amyloidosis was revealed in 2 from 27 pts with systemic type of JIA. 68% of pts had 1 or 2 functional class. 1/3 of pts did not have functional limitations (CHAQ=0. 13% of pts had maximal disability with CHAQ ranging from 2,1 to 3,0 (pts with polyarticular and systemic types of JIA. Most grown up pts (59% considered their health as good. Substantial part of them worked or learned. 10 pts did not worked because of the disease (1,5%. 61% of pts did not have functional limitations (HAQ=0. 32% of pts were disabled. Most of them had 3 or 2 disability degree and had possibility to work. Conclusion. Substantial part of pts with longstanding JIA have stabilization of the disease or remission. Recurrent course of the disease was characterized by decrease of activity. Most children and grown ups with longstanding disease have relatively benign functional outcome. Pts with polyarticular and systemic types of JIA require especial attention because they have maximal risk of joint destruction with severe disability.

  11. MRI based volumetric assessment of knee cartilage after ACL-reconstruction, correlated with qualitative morphologic changes in the joint and with clinical outcome. Is there evidence for early posttraumatic degeneration?; MRT-basierte Knorpelvolumetrie nach Kreuzbandersatzplastik in Korrelation mit qualitativen Gelenkveraenderungen und dem klinischen Outcome. Gibt es Hinweise auf fruehzeitige posttraumatische degenerative Veraenderungen?

    Energy Technology Data Exchange (ETDEWEB)

    Arnoldi, A.P.; Weckbach, S.; Horng, A.; Reiser, M. [Ludwig-Maximilians-Univ. Muenchen (Germany). Dept. of Clinical Radiology; Nussbickel, C. [Klinikum Garmisch-Partenkirchen (Germany). Dept. of Internal Medicine; Noebauer, I. [Medizinische Universitaet Wien (Austria). Klinik fuer Radiodiagnostik; Zysk, S. [Orthopaedie Zentrum Groebenzell (Germany). Center of Orthopaedics; Glaser, C. [NYU Medical Center, New York, NY (United States). Dept. of Radiology

    2011-12-15

    Purpose: The purpose of this study was to analyze potential quantitative and qualitative changes of the knee cartilage and joint indicative of early posttraumatic OA 4 years after ACL-reconstruction and to correlate the MRI-findings with the clinical outcome (CO). Materials and Methods: 1.5 T MRI-scans were performed on 9 patients post-op and 4 years later. Using a high-resolution T 1-w-fs-FLASH-3D-sequence cartilage volume (cVol) and thickness (mTh) were quantified. Using standard PD-w fs and T 1-w sequences qualitative changes of the joint structures were analyzed based on the WORMS-score. CO was rated by an orthopaedic surgeon using Lysholm-score, OAK-score, Tegner-activity-score (TAS), and Arthrometer KT-1000 testing. Results: Mean changes of cVol were -1.8 % (range: -5.9 %; + 0.7 %) and of mTh -0.8 % (range: -3.0 %; + 1.1 %). No significant change (95 %-CI) could be identified for any compartment. Three patients developed new peripatellar ostheophytes, acute trauma related changes mostly decreased. Mean outcome of Lysholm-score and OAK-score were 90 pts and 86 pts, mean TAS was 4.3 pts. Average maximum tibial translation reached 5.2 mm comparing to 6.7 mm on the healthy contralateral side. Conclusion: Despite a tendency towards decreased cVol and mTh 4 years after ACL-reconstruction qMRI revealed no significant cartilage loss. Newly developing osteophytes did not match with the observed good CO. This small pilot study motivates future quantitative and qualitative-structural MRI-based assessment of articular cartilage and other joint structures in order to improve diagnostic tools for the detection of early OA. (orig.)

  12. Literary Study, Measurement, and the Sublime: Disciplinary Assessment

    Science.gov (United States)

    Heiland, Donna, Ed.; Rosenthal, Laura J., Ed.

    2011-01-01

    This collection of essays, "Literary Study, Measurement, and the Sublime: Disciplinary Assessment," edited by Donna Heiland and Laura J. Rosenthal, represents an important new venture in the Foundation's communication program. The book is the product of many authors, including the editors, both of whom have written essays for it. But it is the…

  13. Assessing Meritorious Teacher Performance: A Differential Validity Study.

    Science.gov (United States)

    Ellett, Chad D; Capie, William

    The Teacher Assessment and Development System (TADS) - Meritorious Teacher Program (MTP) FORM instrument is used in the Dade County Public Schools, Miami, Florida, to evaluate teachers. Its validity for decisions concerning merit pay for master teachers was examined in this study. Specifically, its ability to discriminate between high performing…

  14. Assessing the Flipped Classroom in Operations Management: A Pilot Study

    Science.gov (United States)

    Prashar, Anupama

    2015-01-01

    The author delved into the results of a flipped classroom pilot conducted for an operations management course module. It assessed students' perception of a flipped learning environment after making them experience it in real time. The classroom environment was construed using a case research approach and students' perceptions were studied using…

  15. Assessing Student Learning in the Major Field of Study

    Science.gov (United States)

    Volkwein, J. Fredericks

    2010-01-01

    Assessing student attainment in the major field of study is increasingly important to employers and accrediting bodies alike. Construction and manufacturing firms do not like engineers who design faulty bridges and airplanes. Marketing firms want to hire students who understand the difference between a niche market and a global market. School…

  16. Exposure assessment in studies on health effects of traffic exhaust

    Energy Technology Data Exchange (ETDEWEB)

    Setaelae, S. [Association for the Pulmonary Disabled, Helsinki (Finland); Jaakkola, J.J.K. [Helsinki Univ. (Finland). Dept. of Public Health

    1995-12-31

    A main source of outdoor air pollution is road traffic, which produces a complex mixture of nitrogen oxides, carbon monoxide, volatile hydrocarbons, airborne particles and some other compounds. Traffic exhaust affects also the concentrations of ozone and other photo chemical oxidants. In earlier studies those components have had remarkable health effects. Several studies on occupational exposure to automobile exhaust have been published and several studies have been observed an association between both outdoor and indoor pollutant levels and health outcomes. However, there are only a few epidemiological studies in which traffic exhaust, a complex mixture, has been studied in its entirety. During recent years, interesting epidemiological studies of the health effects of this complex mixture have been published. Human exposure assessment for traffic exhaust can be categorized according to the environment of exposure (indoors, outdoors, in-traffic) or to the method of exposure assessment (direct or indirect methods). In this presentation the methods are further categorized into (1) traffic activity, (2) air concentration measurements, and (3) dispersion models, in order to better understand the advantages and disadvantages of different approaches. The objective of this presentation is to make a critical review of exposure assessments in the epidemiological studies on health effects of traffic exhaust. (author)

  17. Self-assessment and students’ study strategies in a community of clinical practice: A qualitative study

    Directory of Open Access Journals (Sweden)

    Hanan M. Al-Kadri

    2012-02-01

    Full Text Available : Self-assessment is recognized as a necessary skill for lifelong learning. It is widely reported to offer numerous advantages to the learner. The research evaluated the impact of students’ and supervisors’ self-assessment and feedback training on students’ perceptions and practices of self-assessment. Moreover, it evaluated the effect of self-assessment process on students’ study strategies within a community of clinical practice.: We conducted a qualitative phenomenological study from May 2008 to December 2009. We held 37 semi-structured individual interviews with three different cohorts of undergraduate medical students until we reached data saturation. The cohorts were exposed to different contexts while experiencing their clinical years’ assessment program. In the interviews, students’ perceptions and interpretations of ‘self-assessment practice’ and ‘supervisor-provided feedback’ within different contexts and the resulting study strategies were explored.: The analysis of interview data with the three cohorts of students yielded three major themes: strategic practice of self-assessment, self-assessment and study strategies, and feedback and study strategies. It appears that self-assessment is not appropriate within a summative context, and its implementation requires cultural preparation. Despite education and orientation on the two major components of the self-assessment process, feedback was more effective in enhancing deeper study strategies.: This research suggests that the theoretical advantages linked to the self-assessment process are a result of its feedback component rather than the practice of self-assessment isolated from feedback. Further research exploring the effects of different contextual and personal factors on students’ self-assessment is needed.

  18. Development Impact Assessment (DIA) Case Study. South Africa

    Energy Technology Data Exchange (ETDEWEB)

    Cox, Sadie [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nawaz, Kathleen [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Sandor, Debra [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-05-19

    This case study reviews South Africa’s experience in considering the impacts of climate change action on development goals, focusing on the South African energy sector and development impact assessments (DIAs) that have and could be used to influence energy policy or inform the selection of energy activities. It includes a review of assessments—conducted by government ministries, technical partners, and academic institutes and non-governmental organizations (NGOs)—that consider employment, health, and water implications of possible energy sector actions, as well as multi-criteria impact assessments.

  19. A human factors needs assessment and planning study

    International Nuclear Information System (INIS)

    A study was done to assess the need for human factors research, development, and regulatory action in the Atomic Energy Control Board. Further study or development in nine human factors areas is proposed. The urgency, schedule, and resources judged to be necessary for the proposed efforts are estimated. Special emphasis is placed on the need for task analysis information, for the evaluation of control room and maintenance human engineering, and for the development of an improved human error reporting system

  20. Development of a Probabilistic Assessment Methodology for Evaluation of Carbon Dioxide Storage

    Science.gov (United States)

    Burruss, Robert A.; Brennan, Sean T.; Freeman, P.A.; Merrill, Matthew D.; Ruppert, Leslie F.; Becker, Mark F.; Herkelrath, William N.; Kharaka, Yousif K.; Neuzil, Christopher E.; Swanson, Sharon M.; Cook, Troy A.; Klett, Timothy R.; Nelson, Philip H.; Schenk, Christopher J.

    2009-01-01

    This report describes a probabilistic assessment methodology developed by the U.S. Geological Survey (USGS) for evaluation of the resource potential for storage of carbon dioxide (CO2) in the subsurface of the United States as authorized by the Energy Independence and Security Act (Public Law 110-140, 2007). The methodology is based on USGS assessment methodologies for oil and gas resources created and refined over the last 30 years. The resource that is evaluated is the volume of pore space in the subsurface in the depth range of 3,000 to 13,000 feet that can be described within a geologically defined storage assessment unit consisting of a storage formation and an enclosing seal formation. Storage assessment units are divided into physical traps (PTs), which in most cases are oil and gas reservoirs, and the surrounding saline formation (SF), which encompasses the remainder of the storage formation. The storage resource is determined separately for these two types of storage. Monte Carlo simulation methods are used to calculate a distribution of the potential storage size for individual PTs and the SF. To estimate the aggregate storage resource of all PTs, a second Monte Carlo simulation step is used to sample the size and number of PTs. The probability of successful storage for individual PTs or the entire SF, defined in this methodology by the likelihood that the amount of CO2 stored will be greater than a prescribed minimum, is based on an estimate of the probability of containment using present-day geologic knowledge. The report concludes with a brief discussion of needed research data that could be used to refine assessment methodologies for CO2 sequestration.

  1. Report of the Study Group on Assessment and Evaluation

    CERN Document Server

    Crouch, R; Netter, K; Crouch, Richard; Gaizuaskas, Robert; Netter, Klaus

    1996-01-01

    This is an interim report discussing possible guidelines for the assessment and evaluation of projects developing speech and language systems. It was prepared at the request of the European Commission DG XIII by an ad hoc study group, and is now being made available in the form in which it was submitted to the Commission. However, the report is not an official European Commission document, and does not reflect European Commission policy, official or otherwise. After a discussion of terminology, the report focusses on combining user-centred and technology-centred assessment, and on how meaningful comparisons can be made of a variety of systems performing different tasks for different domains. The report outlines the kind of infra-structure that might be required to support comparative assessment and evaluation of heterogenous projects, and also the results of a questionnaire concerning different approaches to evaluation.

  2. Study Progress and Trends of Strategic Environmental Assessment in China

    Institute of Scientific and Technical Information of China (English)

    Cai Chunmiao; Shang Jincheng

    2009-01-01

    Strategic environmental assessment (SEA) in China has developed rapidly since it was introduced into China in the 1990s.Chinese government promulgated the Environmental Impact As-sessment Law of China (hereinafter referred to as the EIA Law) in 2002.In this law, it is stipulated clearly that regional and sector plans should be assessed.Through investigating materials and ana-lyzing literatures, this article analyses the practical and academic study achievements of SEA in China that have been achieved since the EIA Law was implemented, probes into the current situation of the main level of SEA in China--plan EIA, then summarizes the development characteristics, and eventually, puts forward the development trends of SEA in China.The research conclusions can offer the foundations for comprehending systematically the progress of SEA in China.

  3. Efficacy and safety of nimesulide long term administration in patients with osteoarthritis: results of 12-months open controlled study DINAMO (long term administration of nimesulide in osteoarthritis multifactor assessment

    Directory of Open Access Journals (Sweden)

    L I Alexeeva

    2009-01-01

    Full Text Available Objective. To compare efficacy and safety of nimesulide and paracetamol in treatment of patients with osteoarthritis (OA during 12 months. Material and methods. 40 women (mean age 66,8±5,1 years with knee osteoarthritis (II-III stage according to Kellgren-Lawrence having intensive pain (>40 mm on VAS were included. Group 1 pts (n=20 received nimesulide 200-100 mg/day. Group 2 pts were treated with paracetamol till 3 g/day. WOMAC was used as efficacy measure. Safety was assessed with endoscopic examination of upper gastrointestinal tract, ECG, blood pressure and ECG Holter monitoring, clinical and biochemical blood parameters. Statistical significance of differences was assessed with Student’s t-test, χ2 and Fisher exact test Results. WOMAC index decreased during treatment from 1182,7±345,9 to 698,4±351,1 for nimesulide and from 1136,4±313,8 to 1031,6±21 for paracetamol (p<0,05. There were 6 cases of gastrointestinal complications and 4 cases of hypertension development or deterioration in each group. Coronary heart disease developed or deteriorated in 4 patients receiving nimesulide but not in control group. Liver function tests did not deteriorated during treatment with nimesulide. Conclusion. Nimesulide was more effective than paracetamol in treatment of OA. But risk of cardiovascular complications development during treatment with NSAIDs requires serious attention. Nimesulide did not induced liver damage during long term treatment.

  4. Approaches to Children's Exposure Assessment: Case Study with Diethylhexylphthalate (DEHP).

    Science.gov (United States)

    Ginsberg, Gary; Ginsberg, Justine; Foos, Brenda

    2016-01-01

    Children's exposure assessment is a key input into epidemiology studies, risk assessment and source apportionment. The goals of this article are to describe a methodology for children's exposure assessment that can be used for these purposes and to apply the methodology to source apportionment for the case study chemical, diethylhexylphthalate (DEHP). A key feature is the comparison of total (aggregate) exposure calculated via a pathways approach to that derived from a biomonitoring approach. The 4-step methodology and its results for DEHP are: (1) Prioritization of life stages and exposure pathways, with pregnancy, breast-fed infants, and toddlers the focus of the case study and pathways selected that are relevant to these groups; (2) Estimation of pathway-specific exposures by life stage wherein diet was found to be the largest contributor for pregnant women, breast milk and mouthing behavior for the nursing infant and diet, house dust, and mouthing for toddlers; (3) Comparison of aggregate exposure by pathways vs biomonitoring-based approaches wherein good concordance was found for toddlers and pregnant women providing confidence in the exposure assessment; (4) Source apportionment in which DEHP presence in foods, children's products, consumer products and the built environment are discussed with respect to early life mouthing, house dust and dietary exposure. A potential fifth step of the method involves the calculation of exposure doses for risk assessment which is described but outside the scope for the current case study. In summary, the methodology has been used to synthesize the available information to identify key sources of early life exposure to DEHP. PMID:27376320

  5. Technetium-99m Sestamibi and [F18]Fluorodeoxyglucose (FDG) PET in assessing patients with multiple myeloma

    International Nuclear Information System (INIS)

    Full text: The aim of the study is to evaluate the diagnostic and prognostic value of 99mTc-Sestamibi (MIBI) in the detection on bone marrow involvement in patients suffering from Multiple Myeloma (MM), its possible role in the follow-up and comparison of 99mTc-MIBI and [F18]FDG PET imaging. We present the results, for patients at our institution, that have undergone 99mTc-MIBI scans to assess MM. We considered patients (pts) with MM (in active disease, partial and chronic remission) and with monoclonal gammopathy of undetermined significance (MGUS). A subgroup of patients with MM repeated a 99mTc-MIBI scintigraphic study at least 2 months after high-dose chemotherapy. All the scans were scored semi-quantitatively according to extension and intensity of tracer uptake. Twelve patients had concurrent 99mTc-MIBI and [F18]FDG PET. The overall sensitivity of the 99mTc-MIBI scintigraphy was 92%, specificity was 96%. In the follow up of the pts treated with chemotherapy 99mTc-sestamibi closely paralleled the activity of myeloma bone disease. A multivariate analysis showed that 99mTc-MIBI uptake pattern has an added value in relation to known prognostic variables. In another study, patients showing disease progression at restaging had higher washout of 99mTc-MIBI (10 and 60 minutes) than patients in remission; disease free survival was significantly better in patients with lower washout in absence of differences in therapeutic regimen and stage of disease at admission. [F18]FDG-PET and MIBI were concordant in seven of 12 cases (58%); only in one case FDG detected bone marrow sites in addition to those detected by 99mTc-MIBI. Our experience indicates that 99mTc-MIBI scintigraphy closely reflects myeloma disease activity in the bone marrow, and that a negative 99mTc-MIBI scan in pts with suspected MM indicates absence of disease or clinical remission. The results of these studies suggest a potential role of 99mTc-MIBI washout in predicting response to chemotherapy in

  6. Environmental impact assessment as a complement of life cycle assessment. Case study: Upgrading of biogas.

    Science.gov (United States)

    Morero, Betzabet; Rodriguez, María B; Campanella, Enrique A

    2015-08-01

    This work presents a comparison between an environmental impact assessment (EIA) and a life cycle assessment (LCA) using a case study: upgrading of biogas. The upgrading of biogas is studied using three solvents: water, physical solvent and amine. The EIA follows the requirements of the legislation of Santa Fe Province (Argentina), and the LCA follows ISO 14040. The LCA results showed that water produces a minor impact in most of the considered categories whereas the high impact in the process with amines is the result of its high energy consumptions. The positive results obtained in the EIA (mainly associated with the cultural and socioeconomic components) make the project feasible and all the negative impacts can be mitigated by preventive and remedial measures. From the strengths and weaknesses of each tool, it is inferred that the EIA is a procedure that can complement the LCA.

  7. A study on safety assessment methodology for a vitrification plant

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Y. C.; Lee, G. S.; Choi, Y. C.; Kim, G. H. [Yonsei Univ., Seoul (Korea, Republic of)

    2002-03-15

    In this study, the technical and regulatory status of radioactive waste vitrification technologies in foreign and domestic plants is investigated and analyzed, and then significant factors are suggested which must be contained in the final technical guideline or standard for the safety assessment of vitrification plants. Also, the methods to estimate the stability of vitrified waste forms are suggested with property analysis of them. The contents and scope of the study are summarized as follows : survey of the status on radioactive waste vitrification technologies in foreign and domestic plants, survey of the characterization methodology for radioactive waste form, analysis of stability for vitrified waste forms, survey and analysis of technical standards and regulations concerned with them in foreign and domestic plants, suggestion of significant factors for the safety assessment of vitrification plants, submission of regulated technical standard on radioactive waste vitrification plats.

  8. Reliability of Pubertal Self Assessment Method: An Iranian Study

    OpenAIRE

    Ali Rabbani; Shahab Noorian; Fallah, Javad S.; Arya Setoudeh; Fatemeh Sayarifard; Farzaneh Abbasi

    2013-01-01

    Objective: This investigation aims to evaluate the validity of a Persian Tanner Stages Self-Assessment QuestionnaireMethods: In this cross sectional study, 190 male students aged 8-16 years selected from three layers of different regions of Tehran (North, Central and South) were enrolled. A Persian questionnaire illustrated with Tanner stages of puberty (genital development and pubic hair distribution) was prepared. Children were asked to select the illustration that best described their pube...

  9. Thorium assessment study quarterly progress report, third quarter fiscal 1977

    Energy Technology Data Exchange (ETDEWEB)

    Spiewak, I.; Bartine, D. E.; Burns, T. J.; Cleveland, J. C.; Thomas, W. E.; White, J. R.

    1977-09-30

    The objective of the program described is to contribute to the ongoing assessment of the potential role of thorium fuel cycles for alleviating safeguards concerns. Scenarios include (1) no fuel recycle permitted, (2) fuel recycle permitted only in secure regions (''energy parks'') with denatured (chemically non-separable) fuels only outside these regions, and (3) no limits on fuel recycle. A further objective is to provide nuclear mass balance data on HTGRs required by ERDA contractors for comparative cost-benefit studies.

  10. Instruments for the assessment of social anxiety disorder: Validation studies

    OpenAIRE

    Osório, Flávia de Lima; Crippa, José Alexandre de Souza; Loureiro, Sonia Regina

    2012-01-01

    Great progress has been observed in the literature over the last decade regarding the validation of instruments for the assessment of Social Anxiety Disorder in the Brazilian context. Particularly outstanding in this respect is the production of a group of Brazilian investigators regarding the psychometric study of the following instruments: Liebowitz Social Anxiety Scale, Social Phobia Inventory, Brief Social Phobia Scale, Disability Profile, Liebowitz Self-Rated Disability Scale, Social Pho...

  11. Assessment of apical periodontitis by MRI. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Geibel, M.A. [Ulm Univ. (Germany). Oral and Maxillofacial Surgery; Schreiber, E.S.; Bracher, A.K.; Rasche, V. [Ulm Univ. (Germany). Internal Medicine II; Hell, E.; Ulrici, J. [Sirona Dental Systems GmbH, Bensheim (Germany). Dental Imaging; Sailer, L.K. [DOC Praxisklinik im Wiley, Neu-Ulm (Germany). MKG; Ozpeynirci, Y. [Ulm Univ. (Germany). Diagnostic and Interventional Radiology

    2015-04-15

    The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility study. Periapical lesions were defined as periapical radiolucencies (CBCT) or structural changes in the spongy bone signal (MRI), which were connected with the apical part of a root and with at least twice the width of the periodontal ligament space. The location and dimension of the lesions were compared between MRI and CBCT. While mainly mineralized tissue components such as teeth and bone were visible with CBCT, complimentary information of the soft tissue components was assessable with MRI. The MRI images provided sufficient diagnostic detail for the assessment of the main structures of interest. Heterogeneous contrast was observed within the lesion, with often a clear enhancement close to the apical foramen and the periodontal gap. No difference for lesion visibility was observed between MRI and CBCT. The lesion dimensions corresponded well, but were slightly but significantly overestimated with MRI. A heterogeneous lesion appearance was observed in several patients. Four patients presented with a well circumscribed hyperintense signal in the vicinity of the apical foramen. The MRI capability of soft tissue characterization may facilitate detailed analysis of periapical lesions. This clinical study confirms the applicability of multi-contrast MRI for the identification of periapical lesions.

  12. Sudbury soils study : summary of volume 3 : ecological risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-03-15

    The Sudbury soils study was comprised of 3 volumes: (1) a background, study organization and 2001 soils survey; (2) a human health risk assessment; and (3) an ecological risk assessment (ERA). This document provided details of the ERA, which was conducted to characterize the current and future risks of chemicals of concern (COC) to terrestrial and ecosystem components from Sudbury smelter particulate emissions. The extent to which COC are preventing the recovery of regionally representative terrestrial plant communities was investigated. Risks to terrestrial wildlife populations and endangered species and communities were evaluated. Samples of soil, water, sediment, plants, terrestrial invertebrates, and fish tissue were collected. Data were then analyzed by scientists and independent consultants in order to assess the impacts of arsenic, cadmium, cobalt, copper, lead, nickel and selenium. Results of the study indicated that terrestrial plant communities in the region continue to be impacted by COC in the soil, as well as by soil erosion, low nutrient levels, and a lack of soil organic matter. Direct impacts on wildlife populations were also observed. 5 refs., 7 tabs., 21 figs.

  13. Explosion approach for external safety assessment: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D. Michael; Halford, Ann [Germanischer Lloyd, Loughborough (United Kingdom); Mendes, Renato F. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

    2009-07-01

    Several questions related to the potential for explosions are explored as this became an important subject during an enterprise risk analysis. The understanding of explosions underwent a substantial evolution in the final 20 years of the 20{sup th} century following international research projects in Europe involving several research institutes, as well gas and oil companies. This led to the development of techniques that could be used to assess the potential consequences of explosions on oil, gas and petrochemical facilities. This paper presents an overview of the potential for explosions in communities close to industrial sites or pipelines right of way (RoW), where the standard explosion assessment methods cannot be applied. With reference to experimental studies, the potential for confined explosions in buildings and Vapor Cloud Explosions is explored. Vapor Cloud Explosion incidents in rural or urban areas are also discussed. The method used for incorporating possible explosion and fire events in risk studies is also described using a case study. Standard explosion assessment methodologies and a revised approach are compared as part of an on going evaluation of risk (author)

  14. Development of a Burn Escharotomy Assessment Tool: A Pilot Study.

    Science.gov (United States)

    Ur, Rebecca; Holmes, James H; Johnson, James E; Molnar, Joseph A; Carter, Jeffrey E

    2016-01-01

    Severe burn injuries can require escharotomies which are urgent, infrequent, and relatively high-risk procedures necessary to preserve limb perfusion and sometimes ventilation. The American Burn Association Advanced Burn Life Support© course educates surgeons and emergency providers about escharotomy incisions but lacks a biomimetic trainer to demonstrate, practice, or provide assessment. The goal was to build an affordable biomimetic trainer with discrete points of failure and pilot a validation study. Fellowship-trained burn and plastic surgeons worked with special effect artists and anatomists to develop a biomimetic trainer with three discrete points of failure: median or ulnar nerve injury, fasciotomy, and failure to check distal pulse. Participants were divided between experienced and inexperienced, survey pre- and post-procedure on a biomimetic model while being timed. The trainer total cost per participant was less than $35. Eighteen participants were involved in the study. The inexperienced (0-1 prior escharotomies performed) had significantly more violations at the discrete points of failure relative to more experienced participants (P = .036). Face validity was assessed with 100% of participants agreement that the model appeared similar to real life and was valuable in their training. Given the advancements in biomimetic models and the need to train surgeons in how to perform infrequent, emergent surgical procedures, an escharotomy trainer is needed today. The authors developed an affordable model with a successful pilot study demonstrating discrimination between experienced and inexperienced surgeons. Additional research is needed to increase the reliability and assessment metrics. PMID:26594860

  15. Development of a Burn Escharotomy Assessment Tool: A Pilot Study.

    Science.gov (United States)

    Ur, Rebecca; Holmes, James H; Johnson, James E; Molnar, Joseph A; Carter, Jeffrey E

    2016-01-01

    Severe burn injuries can require escharotomies which are urgent, infrequent, and relatively high-risk procedures necessary to preserve limb perfusion and sometimes ventilation. The American Burn Association Advanced Burn Life Support© course educates surgeons and emergency providers about escharotomy incisions but lacks a biomimetic trainer to demonstrate, practice, or provide assessment. The goal was to build an affordable biomimetic trainer with discrete points of failure and pilot a validation study. Fellowship-trained burn and plastic surgeons worked with special effect artists and anatomists to develop a biomimetic trainer with three discrete points of failure: median or ulnar nerve injury, fasciotomy, and failure to check distal pulse. Participants were divided between experienced and inexperienced, survey pre- and post-procedure on a biomimetic model while being timed. The trainer total cost per participant was less than $35. Eighteen participants were involved in the study. The inexperienced (0-1 prior escharotomies performed) had significantly more violations at the discrete points of failure relative to more experienced participants (P = .036). Face validity was assessed with 100% of participants agreement that the model appeared similar to real life and was valuable in their training. Given the advancements in biomimetic models and the need to train surgeons in how to perform infrequent, emergent surgical procedures, an escharotomy trainer is needed today. The authors developed an affordable model with a successful pilot study demonstrating discrimination between experienced and inexperienced surgeons. Additional research is needed to increase the reliability and assessment metrics.

  16. Quantitative study designs used in quality improvement and assessment.

    Science.gov (United States)

    Ormes, W S; Brim, M B; Coggan, P

    2001-01-01

    This article describes common quantitative design techniques that can be used to collect and analyze quality data. An understanding of the differences between these design techniques can help healthcare quality professionals make the most efficient use of their time, energies, and resources. To evaluate the advantages and disadvantages of these various study designs, it is necessary to assess factors that threaten the degree with which quality professionals may infer a cause-and-effect relationship from the data collected. Processes, the conduits of organizational function, often can be assessed by methods that do not take into account confounding and compromising circumstances that affect the outcomes of their analyses. An assumption that the implementation of process improvements may cause real change is incomplete without a consideration of other factors that might also have caused the same result. It is only through the identification, assessment, and exclusion of these alternative factors that administrators and healthcare quality professionals can assess the degree to which true process improvement or compliance has occurred. This article describes the advantages and disadvantages of common quantitative design techniques and reviews the corresponding threats to the interpretability of data obtained from their use. PMID:11378972

  17. Offshore risk assessment principles, modelling and applications of QRA studies

    CERN Document Server

    Vinnem, Jan-Erik

    2007-01-01

    attempt has been made to capture the new trends in the regulations, to the extent they are known. There have over the last 10-15 years been published a few textbooks on risk assessment, most of them are devoted to relatively generic topics. Some are also focused on the risk management aspects, in general and with offshore applicability. None are known to address the needs and topics of the use of QRA studies by the offshore industry in particular. The present work is trying to bridge this gap. The use of QRA studies is somewhat special in Northern Europe, and par- cularly in Norway. The use of

  18. Pressurized thermal shock in nuclear power plants: Good practices for assessment. Deterministic evaluation for the integrity of reactor pressure vessel

    International Nuclear Information System (INIS)

    Starting in the early 1970s, a series of coordinated research projects (CRPs) was sponsored by the IAEA focusing on the effects of neutron radiation on reactor pressure vessel (RPV) steels and RPV integrity. In conjunction with these CRPs, many consultants meetings, specialists meetings, and international conferences, dating back to the mid-1960s, were held. Individual studies on the basic phenomena of radiation hardening and embrittlement were also performed to better understand increases in tensile strength and shifts to higher temperatures for the integrity of the RPV. The overall objective of this CRP was to perform benchmark deterministic calculations of a typical pressurized thermal shock (PTS) regime, with the aim of comparing the effects of individual parameters on the final RPV integrity assessment, and then to recommend the best practices for their implementation in PTS procedures. At present, several different procedures and approaches are used for RPV integrity assessment for both WWER 440-230 reactors and pressurized water reactors (PWRs). These differences in procedures and approaches are based, in principle, on the different codes and rules used for design and manufacturing, and the different materials used for the various types of reactor, and the different levels of implementation of recent developments in fracture mechanics. Benchmark calculations were performed to improve user qualification and to reduce the user effect on the results of the analysis. This addressed generic PWR and WWER types of RPV, as well as sensitivity analyses. The complementary sensitivity analyses showed that the following factors significantly influenced the assessment: flaw size, shape, location and orientation, thermal hydraulic assumptions and material toughness. Applying national codes and procedures to the benchmark cases produced significantly different results in terms of allowable material toughness. This was mainly related to the safety factors used and the

  19. Market assessment and technical feasibility study of PFBC ash use

    Energy Technology Data Exchange (ETDEWEB)

    Smith, V.E.; Bland, A.E.; Brown, T.H. [Western Research Inst., Laramie, WY (United States); Georgiou, D.N. [Jacques, Whitford and Associates Ltd., Dartmouth, NS (Canada); Wheeldon, J. [Electric Power Research Inst., Palo Alto, CA (United States)

    1994-10-01

    The overall objectives of this study are to determine the market potential and the technical feasibility of using PFBC ash in high volume ash use applications. The information will be of direct use to the utility industry in assessing the economics of PFBC power generation in light of ash disposal avoidance through ash marketing. In addition, the research is expected to result in the generation of generic data on the use of PFBC ash that could lead to novel processing options and procedures. The specific objectives of the proposed research and demonstration effort are: Define resent and future market potential of PFBC ash for a range of applications (Phase I); assess the technical feasibility of PFBC ash use in construction, civil engineering and agricultural applications (Phase II); and demonstrate the most promising of the market and ash use options in full-scale field demonstrations (Phase III).

  20. Assessing analytical comparability of biosimilars: GCSF as a case study.

    Science.gov (United States)

    Nupur, Neh; Singh, Sumit Kumar; Narula, Gunjan; Rathore, Anurag S

    2016-10-01

    The biosimilar industry is witnessing an unprecedented growth with the newer therapeutics increasing in complexity over time. A key step towards development of a biosimilar is to establish analytical comparability with the innovator product, which would otherwise affect the safety/efficacy profile of the product. Choosing appropriate analytical tools that can fulfil this objective by qualitatively and/or quantitatively assessing the critical quality attributes (CQAs) of the product is highly critical for establishing equivalence. These CQAs cover the primary and higher order structures of the product, product related variants and impurities, as well as process related impurities, and host cell related impurities. In the present work, we use such an analytical platform for assessing comparability of five approved Granulocyte Colony Stimulating Factor (GCSF) biosimilars (Emgrast, Lupifil, Colstim, Neukine and Grafeel) to the innovator product, Neupogen(®). The comparability studies involve assessing structural homogeneity, identity, secondary structure, and product related modifications. Physicochemical analytical tools include peptide mapping with mass determination, circular dichroism (CD) spectroscopy, reverse phase chromatography (RPC) and size exclusion chromatography (SEC) have been used in this exercise. Bioactivity assessment include comparison of relative potency through in vitro cell proliferation assays. The results from extensive analytical examination offer robust evidence of structural and biological similarity of the products under consideration with the pertinent innovator product. For the most part, the biosimilar drugs were found to be comparable to the innovator drug anomaly that was identified was that three of the biosimilars had a typical variant which was reported as an oxidized species in the literature. But, upon further investigation using RPC-FLD and ESI-MS we found that this is likely a conformational variant of the biotherapeutic been

  1. Wuskwatim generation project : Canadian Environmental Assessment Act comprehensive study report

    International Nuclear Information System (INIS)

    This study report described the plan by Manitoba Hydro and the Nisichawayasihk Cree Nation (NCN) to construct a new 200- megawatt (MW) generating station at Taskinigup Falls on the Burntwood River, near the outlet of Wuskwatim Lake. This hydroelectric power project will allow Manitoba Hydro to meet its projected energy needs within the next two decades as identified in its 2002/03 Power Resource Plan. It will also allow Manitoba Hydro and NCN to obtain additional export revenues and profits by advancing the in-service date of the Project from 2020 to 2009. A formal environmental assessment is required under the Canadian Environmental Assessment Act (CEAA) because Fisheries and Oceans Canada (DFO) has determined that the Project would cause fish habitat losses requiring an authorization under the Fisheries Act. Many of the structures to be built in navigable waters would also require formal approval under the Navigable Waters Protection Act (NWPA), which has prompted this application of the CEAA. This environmental assessment report has been prepared by DFO in consultation with Transport Canada and other federal authorities concerned. It provides a summary of the Wuskwatim Generation Project and the environment in which it will be built and operated. In addition, the results of public consultations are discussed. It presents an assessment of the Project's influence on fish and fish habitat, birds, species at risk, human health (local air quality, quality of drinking water and consumption of fishery products), navigation, use of renewable resources, and current use of lands and resources for traditional purposes by Aboriginal persons (hunting, trapping, gathering, subsistence fishing and heritage sites). It was concluded that the proposed Project, as defined by the scope of the study, is not likely to cause significant adverse environmental effects. 45 refs., 5 tabs., 13 figs., 3 appendices

  2. Joint irrigation districts hydropower assessment study. Final feasibility assessment report. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-02-01

    In August 1978, the United States Department of Energy and the Turlock Irrigation District entered into a cooperative agreement for a Joint District's Low-Head Hydropower Assessment Study. The purpose of the agreement was to carry out a study of the hydropower potential at sites within the borders of the Turlock, Merced, South San Joaquin, and Oakdale Irrigation Districts in California. The required data were gathered and analyzed. The results of this study indicate the total potential small hydropower capacity with the Joint Districts is 19,560 kW installed with an annual energy generation of 68,561,800 kWh. This is equivalent to oil-savings of 118,616 barrels per y.

  3. Do formative assessments promote self assessment accuracy? A study of second year medical students’ predictions about performance

    OpenAIRE

    Relan, Anju; Guiton, Gretchen; Sopher, Michael; Goldhaber, Josh

    2006-01-01

    Self assessment accuracy is an essential precursor to the development of self-directed learning- a desired goal of medical education. The purpose of this study was to determine medical students’ long term accuracy of performance prediction, evaluated in the context of formative assessments designed to provide practice for the summative assessment. Students were asked to predict their performance on the final exam over six formative assessments and at the end of the final exam. Students’ co...

  4. Final Technical Report: Renewable Energy Feasibility Study and Resources Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rivero, Mariah [BEC Environmental, Inc., Las Vegas, NV (United States)

    2016-02-28

    In March 2011, the U.S. Department of Energy (DOE) awarded White Pine County, Nevada, a grant to assess the feasibility of renewable resource-related economic development activities in the area. The grant project included a public outreach and training component and was to include a demonstration project; however, the demonstration project was not completed due to lack of identification of an entity willing to locate a project in White Pine County. White Pine County completed the assessment of renewable resources and a feasibility study on the potential for a renewable energy-focused economic sector within the County. The feasibility study concluded "all resources studied were present and in sufficient quantity and quality to warrant consideration for development" and there were varying degrees of potential economic impact based on the resource type and project size. The feasibility study and its components were to be used as tools to attract potential developers and other business ventures to the local market. White Pine County also marketed the County’s resources to the renewable energy business community in an effort to develop contracts for demonstration projects. The County also worked to develop partnerships with local educational institutions, including the White Pine County School District, conducted outreach and training for the local community.

  5. Situated argumentation, learning and science education: A case study of prospective teachers' experiences in an innovative science course

    Science.gov (United States)

    Munford, Danusa

    Various authors had called attention to the significance of argumentation to science education. Nevertheless, argumentation practices had been considerably rare in science classrooms. Moreover, little is know about how people engage in argumentation as science learners to construct knowledge about the natural world and about science. This study was conducted in a science education course for prospective teachers (PTs) at a university in the Northeast United States. The course was composed of three instructional units, focusing on evolution, light and climate change. In each unity, PTs were confronted with questions, and, working in pairs, they built evidence-based arguments. Various types of technology tools were used to support PTs' in that process. The study addresses the experiences of four prospective teachers, adopting a case study research design informed by grounded theory and phenomenology theoretical frameworks. The research questions were: (1) What is the nature of the arguments that PTs' construct? (2) How PTs's understandings about argumentation develop throughout the course? (3) What accounts for PTs' understandings about argument construction? The primary sources of data for the study were (1) electronic artifacts constructed by PTs and (2) interviews with participants conducted after each unit. The structure of their arguments was analyzed to determine the extent to which PTs explored multiple explanations, provided relevant evidence to support their conclusions, explained how evidence and conclusions were related, and recognized limitations in explanations. The results of the study suggest that there are some common trends in the development of understandings about scientific arguments. Initially, learners acknowledged the role of evidence in scientific arguments, and tended to provide evidence to support their claims. However, PTs tended not to explain how these pieces of evidence would be related to their conclusions, and saw little value in

  6. Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS

    Directory of Open Access Journals (Sweden)

    Bradshaw Lucy

    2011-08-01

    Full Text Available Abstract Background Many older people presenting to Acute Medical Units (AMU are discharged after only a short stay ( Method Participants Patients aged > 70 years and scoring positive on a risk screening tool ('Identification of Seniors At Risk' who are discharged within 72 hours of attending an AMU with a medical crisis, recruited prior to discharge. Sample size is 400. Carers of participants will also be recruited. Intervention Assessment on the AMU and further out-patient management by a specialist physician in geriatric medicine. Assessment and further management will follow the principles of Comprehensive Geriatric Assessment, providing advice and support to primary care services. Design Multi-centre, individual patient randomised controlled trial comparing intervention with usual care. Outcome measurement Follow up is by postal questionnaire 90 days after randomisation, and data will be entered into the study database by a researcher blind to allocation. The primary outcome is the number of days spent at home (for those admitted from home, or days spent in the same care home (if admitted from a care home. Secondary outcomes include mortality, institutionalisation, health and social care resource use, and scaled outcome measures, including quality of life, disability, mental well-being. Carer strain and well being will also be measured at 90 days. Analyses Comparisons of outcomes and costs, and a cost utility analysis between the intervention and control groups will be carried out. Trial Registration ISRCTN: ISRCTN21800480

  7. Environmental assessments in the US: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Doesburg, J.M.

    1992-05-01

    The 1990`s is the decade of international environmental activism. The concerns and issues that are the basis of this activism are now extremely important to business. Numerous environmental issue will affect business decisions, and a keen awareness of the implications of those issues may make the difference financial success or ruin. Environmental assessments have become the tool to help business cope with an important environmental concern. This talk is focused on environmental assessments as they are practiced in the United States. Environmental activism has been a factor in business decisions since the passage of the Clean Air Act in 1963. This paper will discuss the current standards of practice in the US, the needs for assessments at industrial facilities, and a case study from a US industrial facility. More than 750,000 commercial real estate transactions take place in the US each year. Each of these transactions has a potential liability for the buyer and lender as a result of environmental impairment caused by hazardous materials located in buildings on sites, in the soil, or in the groundwater. Persons who knowingly or unknowingly acquire environmentally impaired property or who lend the money to purchase that property are liable for the cost of cleanup.

  8. Environmental assessments in the US: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Doesburg, J.M.

    1992-05-01

    The 1990's is the decade of international environmental activism. The concerns and issues that are the basis of this activism are now extremely important to business. Numerous environmental issue will affect business decisions, and a keen awareness of the implications of those issues may make the difference financial success or ruin. Environmental assessments have become the tool to help business cope with an important environmental concern. This talk is focused on environmental assessments as they are practiced in the United States. Environmental activism has been a factor in business decisions since the passage of the Clean Air Act in 1963. This paper will discuss the current standards of practice in the US, the needs for assessments at industrial facilities, and a case study from a US industrial facility. More than 750,000 commercial real estate transactions take place in the US each year. Each of these transactions has a potential liability for the buyer and lender as a result of environmental impairment caused by hazardous materials located in buildings on sites, in the soil, or in the groundwater. Persons who knowingly or unknowingly acquire environmentally impaired property or who lend the money to purchase that property are liable for the cost of cleanup.

  9. Study on Spectral Fatigue Assessment of Trimaran Structure

    Directory of Open Access Journals (Sweden)

    Ren Huilong

    2013-01-01

    Full Text Available This study presents fatigue strength assessment of the trimaran platform by the spectral approach. Spectral fatigue calculations are based on complex stress transfer functions established through direct wave load analysis combined with stress response analysis. In this study, ANSYS software with 3 dimensional linear sea-keeping code AQWA is used to compute frequency response functions of the vessel at zero forward speed. Finite element analysis of global trimaran structure is performed in ANSYS software utilizing hydrodynamic wave loads. Hot spot stress approach is used to compute stress transfer functions of the selected critical details. A MATLAB program, based on direct calculation procedure of spectral fatigue is developed to calculate total fatigue damage using wave scatter data of North Atlantic. Damage incurred during individual heading direction is also calculated and presented by means of polar diagrams to study its contribution towards cumulative fatigue damage.

  10. Assessing interpersonal aspects of schizoid personality disorder: preliminary validation studies.

    Science.gov (United States)

    Kosson, David S; Blackburn, Ronald; Byrnes, Katherine A; Park, Sohee; Logan, Caroline; Donnelly, John P

    2008-03-01

    In 2 studies, we examined the reliability and validity of an interpersonal measure of schizoid personality disorder (SZPD) based on nonverbal behaviors and interpersonal interactions occurring during interviews. A total of 556 male jail inmates in the United States participated in Study 1; 175 mentally disordered offenders in maximum security hospitals in the United Kingdom participated in Study 2. Across both samples, scores on the Interpersonal Measure of Schizoid Personality Disorder (IM-SZ) exhibited adequate reliability and patterns of correlations with other measures consistent with expectations. The scale displayed patterns of relatively specific correlations with interview and self-report measures of SZPD. In addition, the IM-SZ correlated in an expected manner with features of psychopathy and antisocial personality and with independent ratings of interpersonal behavior. We address implications for assessment of personality disorder.

  11. Life cycle assessment study of a Chinese desktop personal computer

    International Nuclear Information System (INIS)

    Associated with the tremendous prosperity in world electronic information and telecommunication industry, there continues to be an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of electronic and electric products (e-products). China's importance as both a consumer and supplier of e-products has grown at an unprecedented pace in recent decade. Hence, this paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese e-products from a global level. A desktop personal computer system has been selected to carry out a detailed and modular LCA which follows the ISO 14040 series. The LCA is constructed by SimaPro software version 7.0 and expressed with the Eco-indicator'99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the so-called CML method is used in order to estimate the influence of the choice of the assessment method on the result. Life cycle inventory information is complied by ecoinvent 1.3 databases, combined with literature and field investigations on the present Chinese situation. The established LCA study shows that that the manufacturing and the use of such devices are of the highest environmental importance. In the manufacturing of such devices, the integrated circuits (ICs) and the Liquid Crystal Display (LCD) are those parts contributing most to the impact. As no other aspects are taken into account during the use phase, the impact is due to the way how the electricity is produced. The final process steps - i.e. the end of life phase - lead to a clear environmental benefit if a formal and modern, up-to-date technical system is assumed, like here in this study

  12. [Ergotherapy assessment: field study of acceptance, practicability and process quality].

    Science.gov (United States)

    Voigt-Radloff, S; Schochat, T; Heiss, H W

    2000-10-01

    There is need for comprehensive assessment of patients suitable for occupational therapy. The "Ergotherapeutische Assessment" (EA) occupational therapy assessment instrument has been developed recently by a group of experts in the field. Its main purpose is to significantly support occupational therapists in diagnostics, planning, communication and evaluation of therapeutic outcome. In a first step, EA was tested in a field study with regard to practicability, acceptance, and its effects on process quality. The EA was applied in 329 patients by 22 occupational therapists (office, institution) who had been specially trained (handbook, instruction session) prior to the study. In addition, participants had to answer standardized evaluation forms with respect to the general therapeutic success, relevant functional changes possibly not covered by the EA, and professional benefit in the areas under investigation. In summary, the value for practicability as described using a 10-point scale was 5.8, and 7.6 for acceptance. With regard to process quality, the ratings were 7.3 for diagnostic effect, 6.0 for definition of therapeutic aims, and 6.8 for improvement of communication between members of the rehabilitation team. The internal consistency of the five individual modules of the instrument as calculated by Cronbachs alpha was between 0.72 and 0.95. Changes considered relevant by the participants and not reflected by the instrument accounted for 9% only. The correlation coefficient for the evaluated general success of the patients and category changes found on the basis of EA severity ratings was 0.48. PMID:11089258

  13. Application of radionuclide techniques in evaluation of dilated cardiomyopathy and ischemic cardiomyopathy

    International Nuclear Information System (INIS)

    Objective: To assess the clinical significance of radionuclide techniques in differentiating dilated cardiomyopathy (DCM) from ischemic cardiomyopathy (CAD-CM). Methods: 28 patients (pts) with DCM and 55 pts with CAD-CM were studied. All pts underwent 99Tcm-MIBI myocardial perfusion SPECT and 18F-FDG myocardial metabolic PET. 73 pts had 99Tcm-RBC radionuclide ventriculography and 68 pts had coronary angiography. Results: 23 pts (82%) with DCM showed perfusion abnormalities with mild and not segmental distribution. 52 pts (95%) with CAD-CM showed perfusion abnormalities that distributed along the coronary vessel territories. Perfusion defects were found in 4 pts (14%) with DCM and 45 pts (82%) with CAD-CM (P<0.01). The average perfusion score was 4.5 +- 2.6 in DCM and 9.5 +- 2.9 in CAD-CM, the area of perfusion diminished uptake was significantly smaller in DCM than in CAD-CM (P < 0.001). 2 pts with DCM and 18 pts with CAD-CM had metabolic defect. The patterns of perfusion/metabolic imaging showed mismatch in most pts with CAD-CM but match in pts with DCM. The LVEF in pts with DCM and CAD-CM was decreased but no significant difference between DCM and CAD-CM was observed. The RVEF in pts with DCM was significantly lower than that in pts with CAD-CM (32.4% +- 13.9% vs 40.9% +- 15.4%, P < 0.05). Conclusions: The radionuclide techniques showed to be helpful for distinguishing DCM from CAD-CM. The discriminate analysis revealed that segmental perfusion abnormality and RVEF were the most important factors for differentiation of DCM from CAD-CM

  14. assessing contributions of jgofs; previewing Studies in Ocean Ecology, Biogeochemistry

    Science.gov (United States)

    Steinberg, Deborah K.; Ducklow, Hugh W.; Buesseler, Ken O.; Bowles, Margaret C.

    Despite impediments to travel imposed by global political and health concerns, 332 scientists and students from 32 countries gathered in Washington, D.C. in early May to celebrate the conclusion of the Joint Global Ocean Flux Study (JGOFS), and to assess both its accomplishments and the future course of research in ocean ecology and biogeochemistry.Launched in 1987 under the auspices of the Scientific Committee on Oceanic Research (SCOR), JGOFS became the first core project of the International Geosphere-Biosphere Programme (IGBP) 2 years later as its first field studies were getting underway. Global in scope and multinational and interdisciplinary from its inception, JGOFS adopted two major goals: to understand the processes controlling the cycling of carbon and other biogenic elements in the ocean and their exchange with the atmosphere and the sea floor, and to advance our capacity to predict the response of ocean systems to anthropogenic perturbations.

  15. Quality control for exposure assessment in epidemiological studies

    DEFF Research Database (Denmark)

    Bornkessel, C; Blettner, M; Breckenkamp, J;

    2010-01-01

    In the framework of an epidemiological study, dosemeters were used for the assessment of radio frequency electromagnetic field exposure. To check the correct dosemeter's performance in terms of consistency of recorded field values over the entire study period, a quality control strategy...... was developed. In this paper, the concept of quality control and its results is described. From the 20 dosemeters used, 19 were very stable and reproducible, with deviations of a maximum of +/-1 dB compared with their initial state. One device was found to be faulty and its measurement data had to be excluded...... from the analysis. As a result of continuous quality control procedures, the confidence in the measurements obtained during the field work was strengthened significantly....

  16. "Assessment of different bioequivalent metrics in Rifampin bioequivalence study "

    Directory of Open Access Journals (Sweden)

    "Rouini MR

    2002-08-01

    Full Text Available The use of secondary metrics has become special interest in bioequivalency studies. The applicability of partial area method, truncated AUC and Cmax/AUC has been argued by many authors. This study aims to evaluate the possible superiority of these metrics to primary metrics (i.e. AUCinf, Cmax and Tmax. The suitability of truncated AUC for assessment of absorption extent as well as Cmax/AUC and partial AUC for the evaluation of absorption rate in bioequivalency determination was investigated following administration of same product as test and reference to 7 healthy volunteers. Among the pharmacokinetic parameters obtained, Cmax/AUCinf was a better indicator or absorption rate and the AUCinf was more sensitive than truncated AUC in evaluation of absorption extent.

  17. Life cycle assessment of active and passive groundwater remediation technologies

    Science.gov (United States)

    Bayer, Peter; Finkel, Michael

    2006-02-01

    Groundwater remediation technologies, such as pump-and-treat (PTS) and funnel-and-gate systems (FGS), aim at reducing locally appearing contaminations. Therefore, these methodologies are basically evaluated with respect to their capability to yield local improvements of an environmental situation, commonly neglecting that their application is also associated with secondary impacts. Life cycle assessment (LCA) represents a widely accepted method of assessing the environmental aspects and potential impacts related to a product, process or service. This study presents the set-up of a LCA framework in order to compare the secondary impacts caused by two conceptually different technologies at the site of a former manufactured gas plant in the city of Karlsruhe, Germany. As a FGS is already operating at this site, a hypothetical PTS of the same functionality is adopted. During the LCA, the remediation systems are evaluated by focusing on the main technical elements and their significance with respect to resource depletion and potential adverse effects on ecological quality, as well as on human health. Seven impact categories are distinguished to address a broad spectrum of possible environmental loads. A main point of discussion is the reliability of technical assumptions and performance predictions for the future. It is obvious that a high uncertainty exists when estimating impact specific indicator values over operation times of decades. An uncertainty analysis is conducted to include the imprecision of the underlying emission and consumption data and a scenario analysis is utilised to contrast various possible technological variants. Though the results of the study are highly site-specific, a generalised relative evaluation of potential impacts and their main sources is the principle objective rather than a discussion of the calculated absolute impacts. A crucial finding that can be applied to any other site is the central role of steel, which particularly derogates

  18. Development and Implementation of Health Technology Assessment: A Policy Study

    Directory of Open Access Journals (Sweden)

    P Abooee

    2013-01-01

    Full Text Available Background: To provide an overview of the development of health technology assessment (HTA in Iran since 2007, and to facilitate further development of HTA and its integration into policy making.Methods: Data of this study were collected through key documents (e.g. literature, laws, and other official documentation and analyzed by experts of opinion in form of qualitative methods.Results: Health technology assessment entered to the political agenda in Iran only in 2007 with a strong impetus of an evidence-based medicine movement with the bellow objectives: Institutionalization of evidence-based decision making in Ministry of Health, Creating an localization for structural HTA in Health system of Iran, Setting up training courses in order to educate capable manpower to full up the capacity of the universities, Establishment of a new field in HTA subject in medical universities for MSc and PhD degree, International communication about HTA through national website and possible participation in international Congress.Conclusion: HTA has been established in the healthcare system of Iran but what is needed is a clear political will to push forward the objectives of HTA in Iran. Similar to other countries, advance the regulation on the adoption of new health technologies to improve not only technical or allocate efficiency, but also health equity.

  19. Pain assessment in animal models: do we need further studies?

    Directory of Open Access Journals (Sweden)

    Gigliuto C

    2014-05-01

    Full Text Available Carmelo Gigliuto,1 Manuela De Gregori,2 Valentina Malafoglia,3 William Raffaeli,3 Christian Compagnone,4 Livia Visai,5,6 Paola Petrini,7 Maria Antonietta Avanzini,9 Carolina Muscoli,8 Jacopo Viganò,11 Francesco Calabrese,11 Tommaso Dominioni,11 Massimo Allegri,2,10 Lorenzo Cobianchi111Anaesthesia and Intensive Care, University of Pavia, Pavia, 2Pain Therapy Service, Fondazione IRCCS Policlinico San Matteo, Pavia, 3ISAL Foundation, Institute for Research on Pain, Torre Pedrera, Rimini, 4Department of Anaesthesia, Intensive Care and Pain Therapy, Azienda Ospedaliera Universitaria Parma, University of Parma, Parma, 5Department of Molecular Medicine, Center for Tissue Engineering (CIT, INSTM UdR of Pavia, University of Pavia, Pavia, 6Department of Occupational Medicine, Ergonomy and Disability, Laboratory of Nanotechnology, Salvatore Maugeri Foundation, IRCCS, Veruno, 7Dipartimento di Chimica, Materiali e Ingegneria Chimica 'G Natta' and Unità di Ricerca Consorzio INSTM, Politecnico di Milano, Milan, 8Department of Health Science, University Magna Grecia of Catanzaro and Centro del Farmaco, IRCCS San Raffaele Pisana, Roma, 9Laboratory of Transplant Immunology/Cell Factory, Fondazione IRCCS Policlinico "San Matteo", Pavia, 10Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, 11University of Pavia, Department of Surgical, Clinical, Paediatric and Diagnostic Science, General Surgery 1, IRCCS Fondazione Policlinico San Matteo, Pavia, ItalyAbstract: In the last two decades, animal models have become important tools in understanding and treating pain, and in predicting analgesic efficacy. Although rodent models retain a dominant role in the study of pain mechanisms, large animal models may predict human biology and pharmacology in certain pain conditions more accurately. Taking into consideration the anatomical and physiological characteristics common to man and pigs (median body size, digestive apparatus

  20. [Economic assessment, a field between clinical research and observational studies].

    Science.gov (United States)

    Launois, Robert

    2003-01-01

    Health technology assessments propose to study the differential impact of health interventions in a complex care system which is characterised by the multitude of individual behaviours and the diverse nature of the institutions involved. Current systems for data collection lend themselves poorly to this rigorous analysis of efficacy of treatments in the actual situations where they are used. Randomised trials endeavour to neutralise any parasitic interference which could compromise testing for a causal relationship between the treatment administered and the result obtained. Their methodology which establishes the term ceteris paribus in the principle of good practice lends itself poorly to an analysis of individual behaviour. Observational studies are start from actual treatment situations to describe them as reliably as possible. By definition, however, these assume that the natural course of events is not deviated by any intervention. The absence of an experimental plan increases the likelihood of bias and makes it more difficult to test for causal relationships. They lend themselves poorly to testing for incremental efficacy. The two instruments to be preferred are decisional analysis and quasi-experimental studies. Decisional analysis help to avoid the problems of external validity associated with randomised clinical trials by associating parameters which are extracted from data obtained from everyday practice. Quasi-experimental studies or pragmatic trials are based on the reality of behaviour of the prescriber and his/her patients; their impact on efficacy, quality of life social costs of the disease and of treatments may be identified under normal conditions of use. PMID:12609811

  1. Assessment of global phase uncertainty in case-control studies

    Directory of Open Access Journals (Sweden)

    van Houwelingen Hans C

    2009-09-01

    Full Text Available Abstract Background In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The measure 1 quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of global relative efficiency a minimum value is suggested. Alternatively, we developed methods directly based on the information content of haplotype frequency estimates to obtain global relative efficiency measures: and based on A- and D-optimality, respectively. All three methods are designed for single populations; they can be applied in cases only, controls only or the whole data. Therefore they are not necessarily optimal for haplotype testing in case-control studies. Results A new global relative efficiency measure was derived to maximize power of a simple test statistic that compares haplotype frequencies in cases and controls. Application to real data showed that our proposed method gave a clear and summarizing measure for the case-control study conducted. Additionally this measure might be used for selection of individuals, who have the highest potential for improving power by resolving phase ambiguity. Conclusion Instead of using relative efficiency measure for cases only, controls only or their combined data, we link uncertainty measure to case-control studies directly. Hence, our global efficiency measure might be useful to assess whether data are informative or have enough power for estimation of a specific haplotype risk.

  2. Assessing maternal healthcare inequities among migrants: a qualitative study

    Directory of Open Access Journals (Sweden)

    Ligia Moreira Almeida

    2014-02-01

    Full Text Available Considering pregnancy and motherhood as periods of increased vulnerability in migrant women, to characterize the healthcare provided to this collective, we sought to identify and understand patterns of satisfaction and demand of maternal and child healthcare, assessing women’s perceptions about its quality. The study followed a qualitative methodology (semi-structured interviews for collecting and analysing data (content analysis and was conducted in Porto, the second largest city of Portugal. Participants were 25 recent immigrant mothers from Eastern European countries, Brazil, Portuguese-speaking African countries and six native Portuguese recent mothers (for comparison, contacted through social associations and institutions. Data suggests that healthcare depends not only on accessibility but especially on social opportunities. Equitable public health action must provide individuals and groups the equal opportunity to meet their needs, which may not be achieved by providing the same standard if care to all.

  3. Recent Results from EO Studies on Indian Carbon Cycle Assessment

    Science.gov (United States)

    Dadhwal, V. K.; Kushwaha, S. P. S.; Singh, S.; Patel, N. R.; Nayak, R. K.; Patil, P.; Dutt, C. B. S.; Murthy, M. S. R.; Jha, C. S.; Rajsekhar, G.; Pujar, G. S.; Trivedi, S.; Sharma, N.; Ali, M. M.

    2011-08-01

    The monsoon based climate system, diverse land use and land cover distribution and cultural practices poses complex issues in monitoring, assessment and simulation of Indian carbon cycle. Several studies reported lack of spatially and temporally consistent databases, need for calibration and validation of models, and development of national frame work to maintain consistency and completeness in efforts and reduction of uncertainty. Considering the need, as part of ISRO Geosphere Biosphere Programme, National Carbon Project (NCP) initiative was taken up to understand and assess land, atmosphere and oceanic components of carbon cycle with a significant scope for integration of remote sensing, geospatial and process based models. The results from the initial studies are discussed in the paper. An increase of the country's forest carbon stocks from 6244.8 to 6621.6 Mt with an annual increment of 37.7 Mt of the carbon from 1995 to 2005 is reported. In the national scale, CASA model based average annual NPP is estimated to be 1.5 Pg C Yr-1 and is increasing at the rate of 0.005 Pg C Yr-2 during past 25 years from 1981-2006. Analysis of Mid tropospheric CO2 levels retrieved from AIRS data since 2002 till now revealed increasing rate of CO2 at 2.14 ppmv yr-1. It was also o found that biosphere uptake over India and oceanic uptake over the south Indian Ocean could play positive role on the control of seasonal variability of atmospheric carbon dioxide growth rate The paper presents further details on different sub components, recent results and challenges ahead of the project.

  4. Integrated assessment in the Mediterranean: the CIRCE case studies

    Science.gov (United States)

    Goodess, C. M.; Agnew, M. D.; Hemming, D.; Giannakopoulos, C.

    2012-04-01

    The heterogeneous nature of the Mediterranean environment, combined with a wide diversity of economic, social and cultural identities, make this region particularly amenable to integrated research on climate change impacts, vulnerabilities, and adaptive response. Within the framework of the EU FP7 CIRCE project, eleven case-study locations were selected to reflect three generic environments (urban, rural and coastal), to quantify current and future climate change and to assess the potential consequences to human communities and ecosystems at the regional to local scale. The case studies (Athens, Beirut, Alexandria, Tuscany, Apulia, Tel Hadya, Judean Foothills, Gulf of Valencia, Gulf of Oran, Gulf of Gabes, West Nile Delta) were chosen to reflect the east-west and north-south contrasts across the Mediterranean, using common selection criteria. A rigorous common framework, referred to as the CIRCE Case studies Integrating Framework was developed to facilitate a structured and systematic basis for identifying and selecting indicators. Within this framework, climate dynamics is viewed as a key driver of changes in social and biogeophysical systems and is modulated by the inherent dynamics of these systems. The top-down, indicator-based approach was complemented by a bottom-up approach involving local and regional stakeholders. A participatory level of involvement was aimed for, with stakeholder dialogue on an informal basis throughout the project, culminating in a series of more formal regional stakeholder workshops. Identification and construction of physical and socio-economic indicators was the most challenging and time-consuming aspect of the case-study work. A detailed set of selection criteria was defined and the process of reviewing and refining indicators was iterative. Nonetheless, a number of data and methodological challenges were encountered. Despite these issues, indicator linkages diagrams provided a useful preparatory stage for structuring the integrated

  5. Scaling studies and conceptual experiment designs for NGNP CFD assessment

    Energy Technology Data Exchange (ETDEWEB)

    D. M. McEligot; G. E. McCreery

    2004-11-01

    The objective of this report is to document scaling studies and conceptual designs for flow and heat transfer experiments intended to assess CFD codes and their turbulence models proposed for application to prismatic NGNP concepts. The general approach of the project is to develop new benchmark experiments for assessment in parallel with CFD and coupled CFD/systems code calculations for the same geometry. Two aspects of the complex flow in an NGNP are being addressed: (1) flow and thermal mixing in the lower plenum ("hot streaking" issue) and (2) turbulence and resulting temperature distributions in reactor cooling channels ("hot channel" issue). Current prismatic NGNP concepts are being examined to identify their proposed flow conditions and geometries over the range from normal operation to decay heat removal in a pressurized cooldown. Approximate analyses have been applied to determine key non-dimensional parameters and their magnitudes over this operating range. For normal operation, the flow in the coolant channels can be considered to be dominant turbulent forced convection with slight transverse property variation. In a pressurized cooldown (LOFA) simulation, the flow quickly becomes laminar with some possible buoyancy influences. The flow in the lower plenum can locally be considered to be a situation of multiple hot jets into a confined crossflow -- with obstructions. Flow is expected to be turbulent with momentumdominated turbulent jets entering; buoyancy influences are estimated to be negligible in normal full power operation. Experiments are needed for the combined features of the lower plenum flows. Missing from the typical jet experiments available are interactions with nearby circular posts and with vertical posts in the vicinity of vertical walls - with near stagnant surroundings at one extreme and significant crossflow at the other. Two types of heat transfer experiments are being considered. One addresses the "hot channel" problem, if necessary

  6. LCTL Teachers’ Assessment Knowledge and Practices: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Megan Montee

    2013-01-01

    Full Text Available Language assessment allows teachers to gather information about student learning and adjust their instructional practices accordingly. When integrated with instruction, assessment can support student-centered teaching by helping instructors understand what students have learned or are able to do and what they still need to know (Shepard, 2000. However, language teachers often receive limited pre-service training in assessment and testing (Malone, 2008. To date, limited empirical work has been conducted about LCTL teacher education and language assessment literacy. This paper explores a teacher training program designed to address the assessment needs of LCTL educators. This program provides a model of evidence-based assessment training that may be useful to other teacher educators. Furthermore, data generated from the project contributes to research about LCTL teacher education and assessment literacy and suggests future directions for work in this area.

  7. Assessing Conifer Ray Parenchyma for Ecological Studies: Pitfalls and Guidelines.

    Science.gov (United States)

    von Arx, Georg; Arzac, Alberto; Olano, José M; Fonti, Patrick

    2015-01-01

    Ray parenchyma is an essential tissue for tree functioning and survival. This living tissue plays a major role for storage and transport of water, nutrients, and non-structural carbohydrates (NSC), thus regulating xylem hydraulics and growth. However, despite the importance of rays for tree carbon and water relations, methodological challenges hamper knowledge about ray intra- and inter-tree variability and its ecological meaning. In this study we provide a methodological toolbox for soundly quantifying spatial and temporal variability of different ray features. Anatomical ray features were surveyed in different cutting planes (cross-sectional, tangential, and radial) using quantitative image analysis on stem-wood micro-sections sampled from 41 mature Scots pines (Pinus sylvestris). The percentage of ray surface (PERPAR), a proxy for ray volume, was compared among cutting planes and between early- and latewood to assess measurement-induced variability. Different tangential ray metrics were correlated to assess their similarities. The accuracy of cross-sectional and tangential measurements for PERPAR estimates as a function of number of samples and the measured wood surface was assessed using bootstrapping statistical technique. Tangential sections offered the best 3D insight of ray integration into the xylem and provided the most accurate estimates of PERPAR, with 10 samples of 4 mm(2) showing an estimate within ±6.0% of the true mean PERPAR (relative 95% confidence interval, CI95), and 20 samples of 4 mm(2) showing a CI95 of ±4.3%. Cross-sections were most efficient for establishment of time series, and facilitated comparisons with other widely used xylem anatomical features. Earlywood had significantly lower PERPAR (5.77 vs. 6.18%) and marginally fewer initiating rays than latewood. In comparison to tangential sections, PERPAR was systematically overestimated (6.50 vs. 4.92%) and required approximately twice the sample area for similar accuracy. Radial cuttings

  8. Assessing conifer ray parenchyma for ecological studies: pitfalls and guidelines

    Directory of Open Access Journals (Sweden)

    Georg evon Arx

    2015-11-01

    Full Text Available Ray parenchyma is an essential tissue for tree functioning and survival. This living tissue plays a major role for storage and transport of water, nutrients and non-structural carbohydrates (NSC, thus regulating xylem hydraulics and growth. However, despite the importance of rays for tree carbon and water relations, methodological challenges hamper knowledge about ray intra- and inter-tree variability and its ecological meaning. In this study we provide a methodological toolbox for soundly quantifying spatial and temporal variability of different ray features.Anatomical ray features were surveyed in different cutting planes (cross-sectional, tangential, and radial using quantitative image analysis on stem-wood micro-sections sampled from 41 mature Scots pines (Pinus sylvestris. The percentage of ray surface (PERPAR, a proxy for ray volume, was compared among cutting planes and between early- and latewood to assess measurement-induced variability. Different tangential ray metrics were correlated to assess their similarities. The accuracy of cross-sectional and tangential measurements for PERPAR estimates as a function of number of samples and the measured wood surface was assessed using bootstrapping statistical technique. Tangential sections offered the best 3D insight of ray integration into the xylem and provided the most accurate estimates of PERPAR, with 10 samples of 4 mm2 showing an estimate within ±6.0% of the true mean PERPAR (relative 95% confidence interval, CI95, and 20 samples of 4 mm2 showing a CI95 of ±4.3%. Cross-sections were most efficient for establishment of time series, and facilitated comparisons with other widely used xylem anatomical features. Earlywood had significantly lower PERPAR (5.77 vs. 6.18% and marginally fewer initiating rays than latewood. In comparison to tangential sections, PERPAR was systematically overestimated (6.50 vs. 4.92% and required approximately twice the sample area for similar accuracy. Radial

  9. Study of creep cavity growth for power plant lifetime assessment

    Energy Technology Data Exchange (ETDEWEB)

    Wu Rui; Sandstroem, Rolf

    2001-01-01

    This report aims to the sub project lifetime assessment by creep (livslaengdspredikteringar vid kryp), which is involved in the project package strength in high temperature power plant, KME 708. The physical creep damage includes mainly cavities and their development. Wu and Sandstroem have observed that cavity size increases linearly with increasing creep strain in a 12%Cr steel. Sandstroem has showed that, based on the relations between the nucleation and growth of creep cavities with creep strain, the physical creep damage can be modelled as a function of creep strain. In the present paper the growth of creep cavity radius R in relation to time t and strain {epsilon} in low alloy and 12%Cr steels as well as a Type 347 steel has been studied. The results exhibit that the power law cavity radius with creep time (R-t) and with creep strain (R-{epsilon}) relations are found for these materials at various testing conditions. The power law R-t and R-{epsilon} relations are in most cases dependent and independent on testing conditions, respectively. The empirical power law R-{epsilon} relations give a description of cavity evolution, which can be used for lifetime assessment. Experimental data have also been compared to the estimations by the classical models for cavity growth, including the power law growth due to Hancock, the diffusion growth due to Speight and Harris, the constrained diffusion growths due to Dyson and due to Rice and the enhanced diffusion growth due to Beere. It appears that the constraint diffusion growth models give a reasonable estimation of R-{epsilon} relation in many cases. The diffusion growth model is only applicable for limited cases where the power over t in R-t relation takes about 1/3. The power law and the enhanced diffusion models are found in most cases to overestimate the cavity growth.

  10. Assessment study of lichenometric methods for dating surfaces

    Science.gov (United States)

    Jomelli, Vincent; Grancher, Delphine; Naveau, Philippe; Cooley, Daniel; Brunstein, Daniel

    2007-04-01

    In this paper, we discuss the advantages and drawbacks of the most classical approaches used in lichenometry. In particular, we perform a detailed comparison among methods based on the statistical analysis of either the largest lichen diameters recorded on geomorphic features or the frequency of all lichens. To assess the performance of each method, a careful comparison design with well-defined criteria is proposed and applied to two distinct data sets. First, we study 350 tombstones. This represents an ideal test bed because tombstone dates are known and, therefore, the quality of the estimated lichen growth curve can be easily tested for the different techniques. Secondly, 37 moraines from two tropical glaciers are investigated. This analysis corresponds to our real case study. For both data sets, we apply our list of criteria that reflects precision, error measurements and their theoretical foundations when proposing estimated ages and their associated confidence intervals. From this comparison, it clearly appears that two methods, the mean of the n largest lichen diameters and the recent Bayesian method based on extreme value theory, offer the most reliable estimates of moraine and tombstones dates. Concerning the spread of the error, the latter approach provides the smallest uncertainty and it is the only one that takes advantage of the statistical nature of the observations by fitting an extreme value distribution to the largest diameters.

  11. Assessment of Corporate Governance in Jordan: An Empirical Study

    Directory of Open Access Journals (Sweden)

    Sinan S. Abbadi

    2011-09-01

    Full Text Available This paper assesses the reality of corporate governance in Jordan. It identifies the framework of corporate governance, which has here been set into two dimensions – institutionalisations and regulations – and describes the five major principles of corporate governance. The study was carried out by interviews with key employees and the review of related laws and selected annual reports. The study found (1 basic shareholder rights were honoured in decision-making, except for large decisions such as major asset sales; (2 shareholders were not treated equitably in practice, although controllers sometimes took action and prohibited insider trading; (3 the role and rights of stakeholders in corporate governance were respected, and stakeholders had a number of legal protections, which were largely covered in Jordan's Company Law; (4 disclosure and transparency were observed to a large extent, although limited to quantity rather than quality, because Jordan has fully adopted IFRS and ISA and (5 boards largely fulfilled their responsibilities, as these are extensively defined by law and regulation.

  12. Quick assessment of hopelessness: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Cheung Yin

    2006-03-01

    Full Text Available Abstract Background Lengthy questionnaires reduce data quality and impose a burden on respondents. Previous researchers proposed that a single item ("My future seems dark to me" and a 4-item component of the Beck's Hopelessness Scale (BHS can summarise most of the information the BHS provides. There is no clear indication of what BHS cutoff values are useful in identifying people with suicide tendency. Methods In a population-based study of Chinese people aged between 15 and 59 in Hong Kong, the Chinese version of the BHS and the Centre for Epidemiologic Studies – Depression scale were administered by trained interviewers and suicidal ideation and suicidal attempts were self-reported. Receiver operating characteristics curve analysis and regression analysis were used to compare the performance of the BHS and its components in identifying people with suicidality and depression. Smoothed level of suicidal tendency was assessed in relation to scores on the BHS and its component to identify thresholds. Results It is found that the 4-item component and, to a lesser extent, the single item of the BHS perform in ways similar to the BHS. There are non-linear relationship between suicidality and scores on the BHS and the 4-item component; cutoff values identified accordingly have sensitivity and specificity of about 65%. Conclusion The 4-item component is a useful alternative to the BHS. Shortening of psycho-social measurement scales should be considered in order to reduce burden on patients or respondents and to improve response rate.

  13. Thermodynamic assessment and experimental study of Mg–Gd alloys

    Energy Technology Data Exchange (ETDEWEB)

    Hampl, M. [Institute of Metallurgy, Clausthal University of Technology, Robert-Koch-Str. 42, D-38678 Clausthal-Zellerfeld (Germany); Blawert, C.; Silva Campos, M.R.; Hort, N.; Peng, Q.; Kainer, K.U. [Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Magnesium Innovation Centre, Max-Planck-Straße 1, D-21502 Geesthacht (Germany); Schmid-Fetzer, R., E-mail: schmid-fetzer@tu-clausthal.de [Institute of Metallurgy, Clausthal University of Technology, Robert-Koch-Str. 42, D-38678 Clausthal-Zellerfeld (Germany)

    2013-12-25

    Highlights: •Solid solubity of Gd in (Mg) experimentally studied. •Consistent thermodynamic calculation of Mg–Gd phase diagram developed. •Vapor pressure and enthalpy of formation data analyzed by Calphad method. •Three error sources identified in earlier approximate enthalpy derivation. •Claimed systematic trends in enthalpies of formation disputed. -- Abstract: The solid solubility of Gd in (Mg) is studied experimentally using microstructure, chemical and EDX analysis on permanent mould chill cast samples which were annealed for 1–14 days at 300–550 °C. Based on those key data and all the critically assessed experimental phase equilibrium and thermodynamic data of the Mg–Gd system two Calphad-type thermodynamic descriptions are developed. This provides calculated phase diagrams, and an inherent inconsistency between the vapor pressure data and the Mg-rich phase diagram is indicated. A previous misperception of “experimental” enthalpy of formation data of binary Gd{sub x}Mg{sub y} intermetallic compounds is also revealed. The assumption of systematic trends in these key thermodynamic data for the series of rare earth elements R = (La, Ce, Pr, Nd, Sm, Gd) is scrutinized.

  14. Comparative study for environmental assessment by program characters

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Suk Chul; Lee, Young Soo; Park, Young Min; Park, Suk Soon; Chung, Kyung Tae; Cho, Hong Yun; Chae, Jang Won; Lee, Sang Don; Lee, Chan Ho; Choi, Joon Kyu; Kim, Kang Joo; Chung, Won Moo; Jin, Jae Yool [Korea Environment Institute, Seoul (Korea)

    1998-12-01

    The level of environmental assessment in Korea was diagnosed by examining the situation of its model for the entire environmental assessment implemented. Also, it proposed an improvement scheme for its problems to be able to advance. It is expected to be utilized as developing optimum model for Korea and establishing a systematic and concrete guideline for environmental assessment modeling. 244 refs., 65 figs., 28 tabs.

  15. Thermal Comfort Assessment: A Case Study at Malaysian Automotive Industry

    Directory of Open Access Journals (Sweden)

    A. R. Ismail

    2009-01-01

    Full Text Available Problem statement: Thermal comfort has a great influence on the productivity and satisfaction of indoor building occupants. The exposure to excessive heat during work may cause discomfort and contributed to low productivity among workers. Malaysia known with its hot and humid weather where in most of the survey study published indicated that workers in Malaysia automotive industries had exposed to excessive temperature while working. The study investigated the thermal comfort level experienced by workers at Malaysian automotive industry. Approach: The study had been conducted at one automotive parts assembly factory in Malaysia. The human subjects for the study constitute operators at tire receiving section of the factory. The environment examined was the relative humidity (%, WBGT, air temperature and radiant temperature (°C of the surrounding workstation area. The environmental factors were measured using Babuc apparatus, which is capable to measure simultaneously those mentioned environmental factors. The time series data of fluctuating level of factors were plotted to identify the significant changes of factors. Then thermal comfort of the workers was assessed by using ASHRAE thermal sensation scale by using Predicted Mean Vote (PMV. Further Predicted Percentage Dissatisfied (PPD was used to estimate the thermal comfort satisfaction of the occupant. Finally the PPD versus PMV were plotted to present the thermal comfort scenario of workers involved in related workstation. Results: The trend of relative humidity curve from the graph also indicated the increasing level of discomfort. The radiant temperature observed seems consistent during the study while there was decreasing of WBGT start from afternoon due to the rain. The study revealed that the PPD value of 54% of the workers population at the workstation are likely to be satisfied with thermal comfort at this station while the PMV index from ASHRAE indicated the value 1

  16. Employing Computer Assisted Assessment (CAA to facilitate formative assessment in the State Secondary School: a case study

    Directory of Open Access Journals (Sweden)

    Effimia Karagianni

    2012-02-01

    Full Text Available Based on theories of assessment as well as on the pedagogical and administrative advantages Computer Assisted Assessment (CAA has to offer in foreign language learning, the study presented in this paper examines how computers can facilitate the formative assessment of EFL learners and enhance their feeling of responsibility towards monitoring their progress. The subjects of the study were twenty five 14-year-old students attending the third class of a State Gymnasium in Greece. The instruments utilized were questionnaires on motivation and learning styles, three quizzes designed with the software Hot Potatoes, a self–assessment questionnaire and an evaluation questionnaire showing the subjects’ attitudes towards the experience of using computers for assessing purposes. After reviewing formative assessment, CAA and how these two can be combined, the paper focuses on the description of the three class quizzes used in the study. Ιnformation from the questionnaires filled in by students combined with the results of the quizzes, shows how computers can be used to provide continuous ongoing measurement of students’ progress needed for formative assessment. The results are also used to show how students and teachers can benefit from formative CAA and the extent to which such kind of assessment could be applicable in the Greek state school reality.

  17. Study of Exclusion and Assessibility of Students with Disabilities in the 1994 Trial State Assessment (TSA) of the National Assessment of Educational Progress (NAEP).

    Science.gov (United States)

    Stancavage, Fran; And Others

    The National Assessment of Educational Progress (NAEP), a survey of national trends in educational achievement, is attempting to expand its inclusion of students with disabilities or limitations that have previously caused them to be excluded from the assessment. The study described was a precursor to the 1996 changes in NAEP inclusion procedures.…

  18. Study on territorial risk assessment in Beibu Gulf of Guangxi

    Science.gov (United States)

    Wang, Y.; Hou, L. S.; Zhang, M. S.

    2016-08-01

    This study is based on the theories of terrestrial exploration risk in the Beibu Gulf Economic Zone in the Guangxi Zhuang Autonomous Region. Using ArcGIS and modelling methods, the spatial distributions of resources and environmental carrying capacity, terrestrial exploration dynamics, and terrestrial exploration potential are studied and evaluated in an integrated way. The results of the study are as follows: Mashan county, Longan county, Luchuan county, et al. have some low-risk land that can be explored, and infrastructure investment should be increased in these locations. Whereas, low-risk terrestrial development is possible in Qinzhou city, Heng county, Longan county, et al. and should be carried out in a planned and gradual fashion. The medium risk regions are distributed all over the region, but are concentrated in the city area of Nanning. However, the middle and north parts of Yulin city, the south part of Chongzuo city, Qinnan district, et al. are also in the same category and priority can be given to improve the quality and efficiency of these regions. The high risk regions, mainly distribute in the Liangqin district, Yining district, Binyang county, et al. This region should focus on the development principles of priority protection, appropriate development, and point-like development. Whereas, the extremely-high-risk areas, of which more than 60% are in Tiandeng county, Daxin county, Shanglin county, et al., are unsuitable for further development. The three-dimensional risk matrix method can make up for the deficiencies of other methods and has broad prospects in regional terrestrial development risk assessment.

  19. Assessing function in patients undergoing joint replacement: a study protocol for a cohort study

    Directory of Open Access Journals (Sweden)

    Wylde Vikki

    2012-11-01

    Full Text Available Abstract Background Joint replacement is an effective intervention for people with advanced arthritis, although there is an important minority of patients who do not improve post-operatively. There is a need for robust evidence on outcomes after surgery, but there are a number of measures that assess function after joint replacement, many of which lack any clear theoretical basis. The World Health Organisation has introduced the International Classification of Functioning, Disability and Health (ICF, which divides function into three separate domains: Impairment, activity limitations and participation restrictions. The aim of this study is to compare the properties and responsiveness of a selection of commonly used outcome tools that assess function, examine how well they relate to the ICF concepts, and to explore the changes in the measures over time. Methods/design Two hundred and sixty three patients listed for lower limb joint replacement at an elective orthopaedic centre have been recruited into this study. Participants attend the hospital for a research appointment prior to surgery and then at 3-months and 1-year after surgery. At each assessment time, function is assessed using a range of measures. Self-report function is assessed using the WOMAC, Aberdeen Impairment, Activity Limitation and Participation Restriction Measure, SF-12 and Measure Yourself Medical Outcome Profile 2. Clinician-administered measures of function include the American Knee Society Score for knee patients and the Harris Hip Score for hip patients. Performance tests include the timed 20-metre walk, timed get up and go, sit-to-stand-to-sit, step tests and single stance balance test. During the performance tests, participants wear an inertial sensor and data from motion analysis are collected. Statistical analysis will include exploring the relationship between measures describing the same ICF concepts, assessing responsiveness, and studying changes in measures over

  20. The Issue of Subjectivity in Authentic Social Studies Assessment.

    Science.gov (United States)

    Nickell, Pat

    1999-01-01

    Suggests that scoring criteria should be used in order to reduce teacher subjectivity in scoring classroom assessments. Describes scoring criteria as specific expectations made clear in task instructions used to evaluate student work. Provides an example assessment task for high school geography and addresses three common teacher errors. (CMK)

  1. Exploring assessment factors contributing to students' study strategies: literature review.

    NARCIS (Netherlands)

    Al-Kadri, H.M.; Al-Moamary, M.S.; Roberts, C.; Vleuten, C.P.M. van der

    2012-01-01

    "Assessment steers students' learning" is a statement that has been used repeatedly without solid evidence in the literature. This manuscript aims to evaluate the published literatures on the effect of teaching learning environment in particular, the implemented assessment on students' learning appr

  2. Study of occupation health risk assessment on Chinese coal mine

    Institute of Scientific and Technical Information of China (English)

    XIAO Guo-qing; YAN Xiang-nong

    2007-01-01

    Factors of occupation health hazard were identified and analyzed, and indexes system of occupation health risk assessment were established by applying fuzzy theory and system safety technique, the weights of index system were obtained by AHP, finally a reasonable mathematics model of occupation health risk assessment was accomplished by an example.

  3. Academic Advising Assessment Practices: Results of a National Study

    Science.gov (United States)

    Powers, Keith L.; Carlstrom, Aaron H.

    2014-01-01

    Best practices of academic advising assessment involve identification of student learning outcomes, the development and use of multiple measures of student learning, and sound professional judgment to understand the information gathered and to improve student learning. However, the assessment results often come from minimal, narrow, and…

  4. Mixture risk assessment: a case study of Monsanto experiences.

    Science.gov (United States)

    Nair, R S; Dudek, B R; Grothe, D R; Johannsen, F R; Lamb, I C; Martens, M A; Sherman, J H; Stevens, M W

    1996-01-01

    Monsanto employs several pragmatic approaches for evaluating the toxicity of mixtures. These approaches are similar to those recommended by many national and international agencies. When conducting hazard and risk assessments, priority is always given to using data collected directly on the mixture of concern. To provide an example of the first tier of evaluation, actual data on acute respiratory irritation studies on mixtures were evaluated to determine whether the principle of additivity was applicable to the mixture evaluated. If actual data on the mixture are unavailable, extrapolation across similar mixtures is considered. Because many formulations are quite similar in composition, the toxicity data from one mixture can be extended to a closely related mixture in a scientifically justifiable manner. An example of a family of products where such extrapolations have been made is presented to exemplify this second approach. Lastly, if data on similar mixtures are unavailable, data on component fractions are used to predict the toxicity of the mixture. In this third approach, process knowledge and scientific judgement are used to determine how the known toxicological properties of the individual fractions affect toxicity of the mixture. Three examples of plant effluents where toxicological data on fractions were used to predict the toxicity of the mixture are discussed. The results of the analysis are used to discuss the predictive value of each of the above mentioned toxicological approaches for evaluating chemical mixtures.

  5. Assessing the use of poplar tree systems as a landfill evapotranspiration barrier with the SHAW model.

    Science.gov (United States)

    Preston, G M; McBride, R A

    2004-08-01

    The use of poplar tree systems (PTS) as evapotranspiration barriers on decommissioned landfills is gaining attention as an option for leachate management. This study involved field-testing the Simultaneous Heat and Water (SHAW) model for its ability to reliably estimate poplar transpiration, volumetric soil water content, and soil temperature at a landfill located in southern Ontario, Canada. The model was then used to estimate deep drainage and to ascertain the influence of a young PTS on the soil water balance of the landfill cover. The SHAW model tended to underestimate poplar transpiration [mean difference (MD) ranged from 0.33 to 3.55 mm on a daily total basis] and overestimate volumetric soil water content by up to 0.10 m3 m(-3). The model estimated soil temperature very well, particularly in the upper 1 m of the landfill cover (MD ranged from -0.1 to 1.6 x degrees C in this layer). The SHAW model simulations showed that deep drainage decreased appreciably with the presence of a young PTS largely through increased interception of rainfall, and that PTS have a good potential to act as effective evapotranspiration barriers in northern temperate climate zones. PMID:15462337

  6. Contaminants in milk and impact of heating: An assessment study

    Directory of Open Access Journals (Sweden)

    Vandana Awasthi

    2012-01-01

    Full Text Available Background: The major contaminants usually encountered in milk and milk products include pesticide residues, heavy metals, and aflatoxin M1 (AFM1. Primarily, milk get contaminated before milching, from the cattle feed, from sources/materials used during the processing of milk as well as improper handling of the milk during the pre- and postprocessing period. Objective: The purpose of this study was to evaluate the effect of household practices on milk contaminants. Materials and Methods: Samples of pasteurized as well as unpasteurized milk (Vendor′s milk were analyzed for AFM1, pesticide residues, and heavy metals. Simulating the household practices, the impact of boiling on these contaminants was assessed. Results: The contaminant Aflatoxin M1 (AFM1 was detected at a concentration ranging from 0.071-0.075 ppb in unpasteurized as well as pasteurized milk samples analyzed during the course of study. Moreover, boiling had no impact on the quantity of AFM1 present in the milk. Pesticides and heavy metal contents were found to be within acceptable limits in all the milk samples tested. Conclusion: Mycotoxins especially aflatoxins in cattle feed and their consequential presence in milk and milk products is a serious concern world over as they are reported carcinogens. These fungal toxins are resistant to high temperatures and may lead to various health hazards. Preventive steps must be taken at each stage to ensure good quality of milk and milk products free from these contaminants. Awareness programs and education for the dairy farmers and milk processors may be helpful in this regard.

  7. 降低峰均值比的时域交织分割PTS算法及分析%Interleaved Partitioning PTS method in time domain for PAPR Reduction

    Institute of Scientific and Technical Information of China (English)

    卢光跃; 邵朝; 马长征

    2008-01-01

    本文根据交织分割部分传输序列(IPTS)的特点,利用具有周期结构的序列DFT的性质,提出基于时域的IPTS算法;同时,将其和常规PTS算法、选择映射算法(SLM)及基于时域循环卷积的PAPR降低算法(TCM)的计算量、性能等进行比较和分析.仿真实验和分析说明本文方法能降低常规IPTS算法的运算量,同时以较小的运算量达到常规相邻分割PTS(APTS)算法的性能.

  8. FY11 Facility Assessment Study for Aeronautics Test Program

    Science.gov (United States)

    Loboda, John A.; Sydnor, George H.

    2013-01-01

    This paper presents the approach and results for the Aeronautics Test Program (ATP) FY11 Facility Assessment Project. ATP commissioned assessments in FY07 and FY11 to aid in the understanding of the current condition and reliability of its facilities and their ability to meet current and future (five year horizon) test requirements. The principle output of the assessment was a database of facility unique, prioritized investments projects with budgetary cost estimates. This database was also used to identify trends for the condition of facility systems.

  9. Assessing Specialized Translation In Academic Contexts: A Case Study

    OpenAIRE

    Kim Grego

    2012-01-01

    This paper discusses translation assessment, first of all by briefly outlining the topic, then by restricting the reflection to specialized translation in didactic contexts and, finally, by discussing how to determine assessment criteria in one specific academic case, the ‘English specialized translation’ course of the ‘Lingue moderne per la comunicazione e la cooperazione internazionale’ Master’s programme of the University of Milan, Italy. Both generic (common to all Master’s programmes in ...

  10. Continuous assessment in process engineering education – two case studies

    OpenAIRE

    Heikkinen, E.-P. (Eetu-Pekka); Jaako, J. (Juha)

    2011-01-01

    BACKGROUND. Development of higher engineering education requires under-standing on teaching, learning and assessment. The content being taught and boundary conditions, such as available resources, must be taken into consideration. In practice it is not possible to implement everything that is presented as desirable in educational research and a compromise is needed, where such a teaching, learning and assessment environment is created that is both theoretically sound and useful in practice. ...

  11. A Study on Public Participation in Environmental Impact Assessments

    Institute of Scientific and Technical Information of China (English)

    WangJing

    2005-01-01

    China's legislature on the environmental impact assessments contains related provisions on public participation as an important element of institutions in this field. So far, however, the stipulation remains at the level of a plain statement of principle both substantially and procedurally. The newly enacted Law on the Assessment of the Environment Impact has seen great progress in provisions for public participation if compared with similar statutes enacted in the past legislation. However, there is a gap in the procedures,

  12. The effect of comorbidities on COPD assessment: a pilot study

    Directory of Open Access Journals (Sweden)

    Weinreich UM

    2015-02-01

    Full Text Available Ulla Møller Weinreich,1–3 Lars Pilegaard Thomsen,2 Barbara Bielaska,4 Vania Helbo Jensen,5,6 Morten Vuust,4 Stephen Edward Rees2 1Department of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Respiratory and Critical Care Group (RCARE, Centre for Model-Based Medical Decision Support Systems, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark; 3The Clinical Institute, Aalborg University Hospital, Aalborg, Denmark; 4Department of Radiology, Vendsyssel Hospital, Hjørring, Denmark; 5Department of Radiology, Horsens Regional Hospital, Horsens, Denmark; 6Department of Radiology, Aalborg University Hospital, Aalborg, Denmark Introduction: Patients with chronic obstructive pulmonary disease (COPD frequently suffer from comorbidities. COPD severity may be evaluated by the Global initiative for chronic ­Obstructive Lung Disease (GOLD combined risk assessment score (GOLD score. Spirometry, body plethysmography, diffusing capacity of the lung for carbon monoxide (DLCO, and high-resolution computed tomography (HR-CT measure lung function and elucidate pulmonary pathology. This study assesses associations between GOLD score and measurements of lung function in COPD patients with and without (≤1 comorbidities. It evaluates whether the presence of comorbidities influences evaluation by GOLD score of COPD severity, and questions whether GOLD score describes morbidity rather than COPD severity.Methods: In this prospective study, 106 patients with stable COPD were included. Patients treated for lung cancer were excluded. Demographics, oxygen saturation (SpO2, modified Medical Research Council Dyspnea Scale, COPD exacerbations, and comorbidities were recorded. Body plethysmography and DLCO were measured, and HR-CT performed and evaluated for emphysema and airways disease. COPD severity was stratified by the GOLD score. Correlation analyses: 1 GOLD score, 2 emphysema grade, and 3 airways disease and lung

  13. PARALLEL MODELS OF ASSESSMENT: INFANT MENTAL HEALTH AND THERAPEUTIC ASSESSMENT MODELS INTERSECT THROUGH EARLY CHILDHOOD CASE STUDIES.

    Science.gov (United States)

    Gart, Natalie; Zamora, Irina; Williams, Marian E

    2016-07-01

    Therapeutic Assessment (TA; S.E. Finn & M.E. Tonsager, 1997; J.D. Smith, 2010) is a collaborative, semistructured model that encourages self-discovery and meaning-making through the use of assessment as an intervention approach. This model shares core strategies with infant mental health assessment, including close collaboration with parents and caregivers, active participation of the family, a focus on developing new family stories and increasing parents' understanding of their child, and reducing isolation and increasing hope through the assessment process. The intersection of these two theoretical approaches is explored, using case studies of three infants/young children and their families to illustrate the application of TA to infant mental health. The case of an 18-month-old girl whose parents fear that she has bipolar disorder illustrates the core principles of the TA model, highlighting the use of assessment intervention sessions and the clinical approach to preparing assessment feedback. The second case follows an infant with a rare genetic syndrome from ages 2 to 24 months, focusing on the assessor-parent relationship and the importance of a developmental perspective. Finally, assessment of a 3-year-old boy illustrates the development and use of a fable as a tool to provide feedback to a young child about assessment findings and recommendations. PMID:27333488

  14. Hydrodynamic and Ecological Assessment of Nearshore Restoration: A Modeling Study

    International Nuclear Information System (INIS)

    Along the Pacific Northwest coast, much of the estuarine habitat has been diked over the last century for agricultural land use, residential and commercial development, and transportation corridors. As a result, many of the ecological processes and functions have been disrupted. To protect coastal habitats that are vital to aquatic species, many restoration projects are currently underway to restore the estuarine and coastal ecosystems through dike breaches, setbacks, and removals. Information on physical processes and hydrodynamic conditions are critical for the assessment of the success of restoration actions. Restoration of a 160- acre property at the mouth of the Stillaguamish River in Puget Sound has been proposed. The goal is to restore native tidal habitats and estuary-scale ecological processes by removing the dike. In this study, a three-dimensional hydrodynamic model was developed for the Stillaguamish River estuary to simulate estuarine processes. The model was calibrated to observed tide, current, and salinity data for existing conditions and applied to simulate the hydrodynamic responses to two restoration alternatives. Responses were evaluated at the scale of the restoration footprint. Model data was combined with biophysical data to predict habitat responses at the site. Results showed that the proposed dike removal would result in desired tidal flushing and conditions that would support four habitat types on the restoration footprint. At the estuary scale, restoration would substantially increase the proportion of area flushed with freshwater (< 5 ppt) at flood tide. Potential implications of predicted changes in salinity and flow dynamics are discussed relative to the distribution of tidal marsh habitat.

  15. Summaries and Technical Documentation for Performance Changes in Citizenship and Social Studies Assessments, 1969-76.

    Science.gov (United States)

    Education Commission of the States, Denver, CO. National Assessment of Educational Progress.

    This report summarizes changes in student performance in the areas of citizenship and social studies, as measured by the National Assessment of Educational Progress. An initial assessment of citizenship was conducted in 1969-70, and an initial assessment of social studies was conducted in 1971-72. Both areas were reassessed in 1975-76. Because…

  16. Quality Assessment of University Studies as a Service: Dimensions and Criteria

    Science.gov (United States)

    Pukelyte, Rasa

    2010-01-01

    This article reviews a possibility to assess university studies as a service. University studies have to be of high quality both in their content and in the administrative level. Therefore, quality of studies as a service is an important constituent part of study quality assurance. When assessing quality of university studies as a service, it is…

  17. 77 FR 70451 - Proposed Collection; Comment Request; Methodological Studies for the Population Assessment of...

    Science.gov (United States)

    2012-11-26

    ... Studies for the Population Assessment of Tobacco and Health (PATH) Study SUMMARY: In compliance with the... Studies for Population Assessment of Tobacco and Health (PATH) Study. Type of Information Collection Request: New. Need and Use of Information Collection: The PATH study will establish a...

  18. STUDYING OF SAFETY CLIMATE ASSESSMENT: A CASE STUDY AT STEEL INDUSTRY

    OpenAIRE

    Hassan DARVISH; Mehdi ROOSTAEI; Azizi, Saeed

    2011-01-01

    Evolution of safety climate used as a practical means has determined and assessed potential problems relevant to safety issues in an organization and can be used in individuals’ performance and work efficiency and decreasing rate of incidents ;as well as; guidance to provide safety organization policy and comparison of safety performance in different organizations. The study wants to determine and prepare safety climate profile and application of its results in improving safety situation. In ...

  19. Relations between student perceptions of assessment authenticity, study approaches and learning outcome

    NARCIS (Netherlands)

    Gulikers, J.T.M.; Bastiaens, Th.J.; Kirschner, P.A.; Kester, L.

    2006-01-01

    This article examines the relationships between perceptions of authenticity and alignment on study approach and learning outcome. Senior students of a vocational training program performed an authentic assessment and filled in a questionnaire about the authenticity of various assessment characterist

  20. Assessment Study of Small Space Debris Removal by Laser Satellites

    Science.gov (United States)

    Choi, Sang H.; Papa, Richard S.

    2011-01-01

    Space debris in Earth orbit poses significant danger to satellites, humans in space, and future space exploration activities. In particular, the increasing number of unidentifiable objects, smaller than 10 cm, presents a serious hazard. Numerous technologies have been studied for removing unwanted objects in space. Our approach uses a short wavelength laser stationed in orbit to vaporize these small objects. This paper discusses the power requirements for space debris removal using lasers. A short wavelength laser pumped directly or indirectly by solar energy can scan, identify, position, and illuminate the target, which will then be vaporized or slow down the orbital speed of debris by laser detonation until it re-enters the atmosphere. The laser-induced plasma plume has a dispersive motion of approximately 105 m/sec with a Lambertian profile in the direction of the incoming beam [1-2]. The resulting fast ejecting jet plume of vaporized material should prevent matter recombination and condensation. If it allows any condensation of vaporized material, the size of condensed material will be no more than a nanoscale level [3]. Lasers for this purpose can be indirectly pumped by power from an array of solar cells or directly pumped by the solar spectrum [4]. The energy required for vaporization and ionization of a 10 cm cube ( 2700 gm) of aluminum is 87,160 kJ. To remove this amount of aluminum in 3 minutes requires a continuous laser beam power of at least 5.38 MW under the consideration of 9% laser absorption by aluminum [5] and 5% laser pumping efficiency. The power needed for pumping 5.38 MW laser is approximately 108 MW, which can be obtained from a large solar array with 40% efficiency solar cells and a minimal area of 450 meters by 450 meters. This solar array would collect approximately 108 MW. The power required for system operation and maneuvering can be obtained by increasing solar panel size. This feasibility assessment covers roughly the power requirement

  1. Study of Value Assessment Model of Forest Biodiversity Based on the Habitat Area in China

    Directory of Open Access Journals (Sweden)

    Ying Zhang

    2014-03-01

    Full Text Available Forest biodiversity is an important part of biodiversity. There is an essential significance of studying forest biodiversity assessment for promoting the conservation of biodiversity and enhancing biodiversity management in China. This study collected forest biodiversity habitat area, output value of forestry and so on forest biodiversity assessment-related data from 2001 to 2010 in China and using optimal control methods in cybernetics to establish value assessment model of forest biodiversity based on the data of habitat area, as well as calculated the optimal price for forest biodiversity assessment. The result showed that forest biodiversity habitat assessment of the optimal price is 9,970 RMB Yuan/ha and there is a dynamic model for forest biodiversity assessment. Finally, the study suggested that studies of forest biodiversity assessment in China, in particular, studying of valuation of forest biodiversity should consider using shadow price and the social, economic and other factors should be taken into account

  2. Risk assessment of contact allergens: a feasibility study

    NARCIS (Netherlands)

    Iersel AAJ van; LEO; LGM; LPI

    1996-01-01

    Skin sensitization, allergic contact dermatitis, is not a life-threatening condition but it can be very impairing. For that reason contemporary legislation prescribes the assessment of the skin sensitizing properties of substances like chemicals, house-hold and personel-care products. In general, sk

  3. Qualitative Assessment across Language Barriers: An Action Research Study

    Science.gov (United States)

    Cronje, Johannes C.

    2009-01-01

    If students cannot express themselves in the language of the assessor, and if the assessor is not familiar with the cultural constraints within which students operate, it is difficult for the assessor to collect evidence of adequate performance. This article describes the assessment of three digital artefacts where the assessor strove to…

  4. Alternative Assessment: Implications for Social Studies. ERIC Digest.

    Science.gov (United States)

    Nickell, Pat

    Alternative forms of evaluating student progress are changing testing or assessment in U.S. schools. From the teacher-made to the standardized test, the familiar over-emphasis on multiple-choice items is giving way to expanded generative formats in which students are called upon to demonstrate mastery through applications in which they use complex…

  5. Cultural Shifts, Multimodal Representations, and Assessment Practices: A Case Study

    Science.gov (United States)

    Curwood, Jen Scott

    2012-01-01

    Multimodal texts involve the presence, absence, and co-occurrence of alphabetic text with visual, audio, tactile, gestural, and spatial representations. This article explores how teachers' evaluation of students' multimodal work can be understood in terms of cognition and culture. When teachers apply a paradigm of assessment rooted in print-based…

  6. A novel assessment of adolescent mobility: a pilot study

    DEFF Research Database (Denmark)

    Stewart, Tom; Duncan, Scott; Chaix, Basile;

    2015-01-01

    neighbourhood boundaries were assessed. Data were imported into ArcGIS and street network distances between the home and each geolocated destination were generated. Convex hull activity spaces were derived from destinations. Urban form variables and geometric characteristics were compared between the perceived...

  7. Red list assessment of European habitat types. A feasibility study

    NARCIS (Netherlands)

    Rodwell, J.S.; Janssen, J.A.M.; Gubbay, S.; Schaminee, J.H.J.

    2013-01-01

    This report presents an achievable methodology for the Red List assessment of European habitats in terrestrial, freshwater and marine realms, outlines a process that will deliver such evaluations and gives an indication of resources needed. It shows how the EUNIS habitat classification can be employ

  8. Beyond the Bubble in History/Social Studies Assessments

    Science.gov (United States)

    Breakstone, Joel; Smith, Mark; Wineburg, Sam

    2013-01-01

    Teachers need tools and assessments that will prepare students to meet the ambitious goals laid out by the Common Core State Standards. The multiple-choice tests that dominate in history will not prepare students to analyze primary and secondary sources, cite textual evidence to support arguments, consider the influence of an author's perspective,…

  9. Quantum Mechanics Concept Assessment: Development and Validation Study

    Science.gov (United States)

    Sadaghiani, Homeyra R.; Pollock, Steven J.

    2015-01-01

    As part of an ongoing investigation of students' learning in first semester upper-division quantum mechanics, we needed a high-quality conceptual assessment instrument for comparing outcomes of different curricular approaches. The process of developing such a tool started with converting a preliminary version of a 14-item open-ended quantum…

  10. Institutional Assessment of Student Information Literacy Ability: A Case Study

    Science.gov (United States)

    Chan, Christopher

    2016-01-01

    With increasing interest in the assessment of learning outcomes in higher education, stakeholders are demanding concrete evidence of student learning. This applies no less to information literacy outcomes, which have been adopted by many colleges and universities around the world. This article describes the experience of a university library in…

  11. Review of pressurized thermal shock studies of large scale reactor pressure vessels in Hungary

    Directory of Open Access Journals (Sweden)

    Tamás Fekete

    2016-03-01

    Full Text Available In Hungary, four nuclear power units were constructed more than 30 years ago; they are operating to this day. In every unit, VVER-440 V213-type light-water cooled, light-water moderated, ressurized water reactors are in operation. Since the mid-1980s, numerous researches in the field of Pressurized Thermal Shock (PTS analyses of Reactor Pressure Vessels (RPVs have been conducted in Hungary; in all of them, the concept of structural integrity was the basis of research and development. During this time, four large PTS studies with industrial relevance have been completed in Hungary. Each used different objectives and guides, and the analysis methodology was also changing. This paper gives a comparative review of the methodologies used in these large PTS Structural Integrity Analysis projects, presenting the latest results as well

  12. Risk Assessment of Vertical Breakwaters -- A Case Study in Turkey

    Institute of Scientific and Technical Information of China (English)

    Can Elmar BALAS; Levent KOC

    2002-01-01

    In the reliability-risk assessment, the second order reliability index (βⅡ) method and the Conditional ExpectationMonte Carlo (CEMC) simulation are interrelated as a new Level Ⅲ approach for the analysis of the safety level of theDalaman yacht harbor vertical wall breakwater in Turkey. The missing wave data of the Dalaman measurement station arehindcasted by use of muhi-layer feed-forward neural networks with the steepest descent and conjugate gradient algorithms.The structural failure probabilities of sliding and overturning failure modes are forecasted by approximation of the failure sur-face with a second-degree polynomial of an equal curvature at the design point. In the new approach, for each randomlygenerated load and tide combination, the joint failure probability reflects both the occurrence probability of loading conditionand the structural failure risk at the limit state. The approach can be applied to risk assessment of vertical breakwaters inshort CPU durations of portable computers.

  13. Cognitive Assessment System (CAS): Psychometric studies with Portuguese children.

    OpenAIRE

    Rosário, A.; Candeias, A.A.; Roazzi, A.

    2013-01-01

    The Cognitive Assessment System (CAS) is a new measure of cognitive abilities based on the Planning, Attention, Simultaneous and Successive (PASS) Theory. This theory is derived from research in neuropsychological and cognitive Psychology with particular emphasis on the work of Luria (1973). According to Naglieri (1999) and Naglieri and Das (1997), the PASS cognitive processes are the basic building blocks of human intellectual functioning. Planning processes provide cognitive control, utiliz...

  14. A Study of Arbitrations in Pennsylvania's Writing Assessment.

    Science.gov (United States)

    Masters, James R.

    In 1991 Pennsylvania began implementation of a direct writing assessment at the sixth-grade and ninth-grade levels. A total of 18,758 sixth graders and 16,575 ninth graders wrote a response to 1 of 9 prompts reflecting 3 modes of writing. A six-point holistic scale was used to score the papers, with two readers scoring each paper. A third reader,…

  15. A novel assessment of adolescent mobility: a pilot study

    OpenAIRE

    Stewart, Tom; Duncan, Scott; Chaix, Basile; Kestens, Yan; Schipperijn, Jasper; Schofield, Grant

    2015-01-01

    Background The accurate measurement of daily mobility and travel to destinations beyond the residential neighbourhood has been identified as an important but almost systematically overlooked factor when investigating the relationship between exposure to the built environment and physical activity. The recent development of VERITAS – a web-based application nested within a computer-assisted personal interview – allows researchers to assess daily mobility, travel to regular destinations, and pe...

  16. Teaching Writing in the Shadow of Standardized Writing Assessment: An Exploratory Study

    Science.gov (United States)

    Brimi, Hunter

    2012-01-01

    This exploratory study results from interviews with five high school English teachers regarding their writing instruction. The researcher sought to answer these questions: (1) How had the Tennessee Comprehensive Assessment Program's (TCAP) Writing Assessment affected their teaching as gauged by the teachers' statements regarding the assessment,…

  17. The effect of practical experience on perceptions of assessment authenticity, study approach and learning outcome

    NARCIS (Netherlands)

    Gulikers, J.T.M.; Kester, L.; Kirschner, P.A.; Bastiaens, Th.J.

    2008-01-01

    Does authentic assessment or the perception of it affect how students study and learn? Does practical experience affect how assessment authenticity is perceived? And does practical experience influence how an authentic assessment affects student learning? Mixed methods design yielded insight into th

  18. Assessment Criteria for Competency-Based Education: A Study in Nursing Education

    Science.gov (United States)

    Fastré, Greet M. J.; van der Klink, Marcel R.; Amsing-Smit, Pauline; van Merriënboer, Jeroen J.

    2014-01-01

    This study examined the effects of type of assessment criteria (performance-based vs. competency-based), the relevance of assessment criteria (relevant criteria vs. all criteria), and their interaction on secondary vocational education students' performance and assessment skills. Students on three programmes in the domain of nursing and care…

  19. Objectifying facial expressivity assessment of Parkinson's patients: preliminary study.

    Science.gov (United States)

    Wu, Peng; Gonzalez, Isabel; Patsis, Georgios; Jiang, Dongmei; Sahli, Hichem; Kerckhofs, Eric; Vandekerckhove, Marie

    2014-01-01

    Patients with Parkinson's disease (PD) can exhibit a reduction of spontaneous facial expression, designated as "facial masking," a symptom in which facial muscles become rigid. To improve clinical assessment of facial expressivity of PD, this work attempts to quantify the dynamic facial expressivity (facial activity) of PD by automatically recognizing facial action units (AUs) and estimating their intensity. Spontaneous facial expressivity was assessed by comparing 7 PD patients with 8 control participants. To voluntarily produce spontaneous facial expressions that resemble those typically triggered by emotions, six emotions (amusement, sadness, anger, disgust, surprise, and fear) were elicited using movie clips. During the movie clips, physiological signals (facial electromyography (EMG) and electrocardiogram (ECG)) and frontal face video of the participants were recorded. The participants were asked to report on their emotional states throughout the experiment. We first examined the effectiveness of the emotion manipulation by evaluating the participant's self-reports. Disgust-induced emotions were significantly higher than the other emotions. Thus we focused on the analysis of the recorded data during watching disgust movie clips. The proposed facial expressivity assessment approach captured differences in facial expressivity between PD patients and controls. Also differences between PD patients with different progression of Parkinson's disease have been observed. PMID:25478003

  20. A Study of an Intelligent Battlefield Damage Assessment System Based on a Multi-agent System

    Institute of Scientific and Technical Information of China (English)

    LIU Xiang-kai; DAI Wan-jun; TANG Yan-feng; WANG Jia-ning

    2008-01-01

    Battlefield damage assessment is the key to Battlefield Damage Assessment and Repair (BDAR).We present an Intelligent Battlefield Damage Assessment System (IBDAS) based on multi-agent system technology. We first establish the system framework, and then study the interior structure and workflow of a problem allocation agent. The result shows that, there are many advantages to resolve the problem of battlefield damage assessment by applying multi-agent system technology, and it will bring significant military benefit.

  1. Tissue quality assessment using a novel direct elasticity assessment device (the E-finger: a cadaveric study of prostatectomy dissection.

    Directory of Open Access Journals (Sweden)

    Daniel W Good

    Full Text Available Minimally invasive radical prostatectomy (RP (robotic and laparoscopic, have brought improvements in the outcomes of RP due to improved views and increased degrees of freedom of surgical devices. Robotic and laparoscopic surgeries do not incorporate haptic feedback, which may result in complications secondary to inadequate tissue dissection (causing positive surgical margins, rhabdosphincter damage, etc. We developed a micro-engineered device (6 mm2 sized [E-finger] capable of quantitative elasticity assessment, with amplitude ratio, mean ratio and phase lag representing this. The aim was to assess the utility of the device in differentiating peri-prostatic tissue types in order to guide prostate dissection.Two embalmed and 2 fresh frozen cadavers were used in the study. Baseline elasticity values were assessed in bladder, prostate and rhabdosphincter of pre-dissected embalmed cadavers using the micro-engineered device. A measurement grid was created to span from the bladder, across the prostate and onto the rhabdosphincter of fresh frozen cadavers to enable a systematic quantitative elasticity assessment of the entire area by 2 independent assessors. Tissue was sectioned along each row of elasticity measurement points, and stained with haematoxylin and eosin (H&E. Image analysis was performed with Image Pro Premier to determine the histology at each measurement point.Statistically significant differences in elasticity were identified between bladder, prostate and sphincter in both embalmed and fresh frozen cadavers (p = < 0.001. Intra-class correlation (ICC reliability tests showed good reliability (average ICC = 0.851. Sensitivity and specificity for tissue identification was 77% and 70% respectively to a resolution of 6 mm2.This cadaveric study has evaluated the ability of our elasticity assessment device to differentiate bladder, prostate and rhabdosphincter to a resolution of 6 mm2. The results provide useful data for which to continue to

  2. Substances toxiques persistantes (PTS dans les corps gras : État des lieux d’après le rapport du programme des Nations-Unies pour l’environnement (PNUE

    Directory of Open Access Journals (Sweden)

    Narbonne Jean François

    2003-07-01

    Full Text Available Depuis plus de trente ans, une attention croissante a été portée sur les risques pour la santé humaine posés par la contamination de l’environnement par les substances toxiques persistantes (PTS. Ces composés persistent pendant de longues périodes dans les compartiments abiotiques et biotiques, sont transportés sur de longues distances depuis leurs points sources et s’accumulent chez l’homme et les organismes via les chaînes alimentaires. En 1997, le PNUE propose une liste initiale de 12 substances appelées polluants organiques persistants (POPs : aldrine, endrine, dieldrine, chordane, DDT, heptachlore, toxaphène, mirex, hexachlorobenzène, PCBs, dioxines (PCDDs, furanes (PCDFs. En 2001, de nouveaux composés sont ajoutés sur la liste des PTS en fonction de leurs caractéristiques comme la liposolubilité, leur résistance à la dégradation, leur forte toxicité ou la constance des apports : hexachlorohexane, PAHs, endosulfan, pentachlorophénol, formes organiques des métaux lourds : mercure, étain et plomb, phtalates, PBDEs\\\\PBBs, chlordécone, alkyl phénols, atrazine. Les sources de PTS sont diverses : (1 Utilisation de produits chimiques industriels comme les pesticides ou les emballages, (2 Réservoirs historiques déjà présents dans l’environnement essentiellement dans les sols et les sédiments ou sous forme de stocks périmés, (3 Sous-produits de process, en particulier comme contaminants indésirables de procédés industriels et de combustion. La France a été associée au rapport de la région IV méditerranéenne. Les niveaux dans les compartiments de l’environnement sont rapportés et l’exposition de l’homme via l’alimentation (vecteur essentiel est estimée en fonction des données collectées. Une évaluation des risques associés a été faite quand les données étaient suffisantes (PAHs, PCBs, PCDD\\\\F, Me Hg. Les lipides apparaissent comme vecteurs majeurs des PTS à travers la cha

  3. Site-Specific ecological risk assessment. Case-study 2

    DEFF Research Database (Denmark)

    Jensen, John

    The decision supporting and integrating assessment tool, TRIAD, is used site-specific on PAH- and heavy metal contaminated sites in Denmark. The various aspects of the TRIAD approach are used on a set of chemistry-, ecotoxicology- and ecology related data collected among others in the EU project...... “Development of a decision support system for sustainable management of contaminated land by linking bioavailability, ecological risk and ground water pollution of organic pollutants”or in short “LIBERATION”. The presentation includes examples on how to scale and integrate the results from various scientific...

  4. A Comparative Study of Three Vibration Based Damage Assessment Techniques

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Rytter, A.

    Three different vibration based damage assessment techniques have been compared. One of the techniques uses the ratios between changes in experimentally and theoretically estimated natural frequencies, respectively, to locate a damage. The second technique relies on updating of an FEM based...... on experimentally estimated natural frequencies where the stiffness matrix is given as a function of damage size and location. The last technique is based on neural networks trained with the relative changes in natural frequencies. It has been found that all techniques seems to be useful. Especially, the neural...... networks based technique seems to be very promising....

  5. The study of the life cycle of technology assessment model

    Institute of Scientific and Technical Information of China (English)

    SHEN Yu-Zhi; HUANG Xun-jiang

    2001-01-01

    The life cycle of technology is one of the most important indexes to weigh up the risk of the investment to neo-tech. There are so many uncertainties because it is conditioned by a lot of factors, we can not make a rational forecasting by traditional assessment method. So this paper gives a conprehensive consideration to the factors that influence production and makes some modification to production function, and establishes the life cycle of technology assessmet model by the method of fuzzy mathematics. So it quantifies the risk of investment. We can take it as one foundational index for the decision making of the investment.

  6. Do you feel the difference? – A motion assessment study

    OpenAIRE

    Brünger-Koch, Martin; Briest, Susanne; Vollrath, Mark

    2006-01-01

    Since June 2005, a new moving-base driving Simulator (6 DoF) is in operation at the DLR Institute of Transportation Systems. Initial experiments were conducted in order to evaluate the participant’s ability to control a car within a virtual environment with different motion platform characteristics. In addition, the subjects assessed the quality of the perceived motion. The driving behaviour in the simulator was compared to driving in the real world with an equipped car (the DLR ViewCar). ...

  7. Integrating risk assessment and life cycle assessment: a case study of insulation.

    Science.gov (United States)

    Nishioka, Yurika; Levy, Jonathan I; Norris, Gregory A; Wilson, Andrew; Hofstetter, Patrick; Spengler, John D

    2002-10-01

    Increasing residential insulation can decrease energy consumption and provide public health benefits, given changes in emissions from fuel combustion, but also has cost implications and ancillary risks and benefits. Risk assessment or life cycle assessment can be used to calculate the net impacts and determine whether more stringent energy codes or other conservation policies would be warranted, but few analyses have combined the critical elements of both methodologies In this article, we present the first portion of a combined analysis, with the goal of estimating the net public health impacts of increasing residential insulation for new housing from current practice to the latest International Energy Conservation Code (IECC 2000). We model state-by-state residential energy savings and evaluate particulate matter less than 2.5 microm in diameter (PM2.5), NOx, and SO2 emission reductions. We use past dispersion modeling results to estimate reductions in exposure, and we apply concentration-response functions for premature mortality and selected morbidity outcomes using current epidemiological knowledge of effects of PM2.5 (primary and secondary). We find that an insulation policy shift would save 3 x 10(14) British thermal units or BTU (3 x 10(17) J) over a 10-year period, resulting in reduced emissions of 1,000 tons of PM2.5, 30,000 tons of NOx, and 40,000 tons of SO2. These emission reductions yield an estimated 60 fewer fatalities during this period, with the geographic distribution of health benefits differing from the distribution of energy savings because of differences in energy sources, population patterns, and meteorology. We discuss the methodology to be used to integrate life cycle calculations, which can ultimately yield estimates that can be compared with costs to determine the influence of external costs on benefit-cost calculations. PMID:12442994

  8. Questioning western assessment of trauma among Tibetan torture survivors. A quantitative assessment study with comments from Buddhist Lamas

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Jespersen, Kristian;

    2009-01-01

    Our study falls in line with the numerous studies providing a critique of the use of western diagnostic instruments for assessing trauma in a cross-cultural context. Our purpose has been to give evidence for the Tibetan torture survivors' degree of traumatisation and for their use of spirituality...... not have an influence on the level of distress. After the assessment study, eight Tibetan lamas were interviewed about their views on our methods and results. They questioned the validity of our western rating scales and explained that our results might be influenced by the Tibetan culture, which among...... other things can be characterized as having a view and articulation of suffering much more complex than the units of our study's rating scales....

  9. Assessment of SPM in perfusion brain SPECT studies. A numerical simulation study using bootstrap resampling methods.

    Science.gov (United States)

    Pareto, Deborah; Aguiar, Pablo; Pavía, Javier; Gispert, Juan Domingo; Cot, Albert; Falcón, Carles; Benabarre, Antoni; Lomeña, Francisco; Vieta, Eduard; Ros, Domènec

    2008-07-01

    Statistical parametric mapping (SPM) has become the technique of choice to statistically evaluate positron emission tomography (PET), functional magnetic resonance imaging (fMRI), and single photon emission computed tomography (SPECT) functional brain studies. Nevertheless, only a few methodological studies have been carried out to assess the performance of SPM in SPECT. The aim of this paper was to study the performance of SPM in detecting changes in regional cerebral blood flow (rCBF) in hypo- and hyperperfused areas in brain SPECT studies. The paper seeks to determine the relationship between the group size and the rCBF changes, and the influence of the correction for degradations. The assessment was carried out using simulated brain SPECT studies. Projections were obtained with Monte Carlo techniques, and a fan-beam collimator was considered in the simulation process. Reconstruction was performed by using the ordered subsets expectation maximization (OSEM) algorithm with and without compensation for attenuation, scattering, and spatial variant collimator response. Significance probability maps were obtained with SPM2 by using a one-tailed two-sample t-test. A bootstrap resampling approach was used to determine the sample size for SPM to detect the between-group differences. Our findings show that the correction for degradations results in a diminution of the sample size, which is more significant for small regions and low-activation factors. Differences in sample size were found between hypo- and hyperperfusion. These differences were larger for small regions and low-activation factors, and when no corrections were included in the reconstruction algorithm.

  10. Strategic Assessment Model and Its Application:a Case Study

    Institute of Scientific and Technical Information of China (English)

    ZHU Xiu-wen; CAO Meng-xia; ZHU Ning; ZUO M1ng-j1an

    2001-01-01

    Accurate and effective assessment of strategic alternatives of an organization directly affects the decision-making and execution of its development strategy. In evaluation of strategic alternatives, relevant elements from both internal and external environments of an organization must be considered. In this paper we use strategic assessment model to evaluate strategic alternatives of an air-conditioning company. Strategic objectives and alternatives of the company are developed through analysis of the competitive environment,key competitors and internal conditions. The environment factors are classified into internal, task, and general opportunities and threats. Analytical hierarchy process, subjective probabilities, entropy concept,and utility theory are used to enhance decision-maker's ability in evaluating strategic alternatives. The evaluation results show that the most effective strategic alternative for the company is to reduce types of products, concentrate its effort on producing window-type and cupboard-type air-conditioners, enlarge the production scale, and pre-empt the market. The company has made great progress by implementing this alternative. We conclude that SAM is an appropriate tool for evaluating strategic alternatives.

  11. 1982 Aleutian Islands salmon stock assessment study: Legislative report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a comprehensive research study of the Aleutian Islands salmon resources in 1982. The study encompassed the area west of Unimak Pass to Attu...

  12. STUDYING OF SAFETY CLIMATE ASSESSMENT: A CASE STUDY AT STEEL INDUSTRY

    Directory of Open Access Journals (Sweden)

    Hassan DARVISH

    2011-01-01

    Full Text Available Evolution of safety climate used as a practical means has determined and assessed potential problems relevant to safety issues in an organization and can be used in individuals’ performance and work efficiency and decreasing rate of incidents ;as well as; guidance to provide safety organization policy and comparison of safety performance in different organizations. The study wants to determine and prepare safety climate profile and application of its results in improving safety situation. In this study, applied tools presented by Loughborough University are used to evaluate safety climate in one of steel industries and data is collected through questionnaire, group discussions or purposeful interviews and observations, and safety climate score was obtained in 17 scopes. Calculating the score of each safety climate domain and preparing the profile indicated there is the average rate (4.89 2 in the safety climate of the industry.

  13. Assessment of polymorphic metabolite data in bioavailability/bioequivalence studies - considerations and challenges

    Directory of Open Access Journals (Sweden)

    Nuggehally R Srinivas

    2011-01-01

    Full Text Available Bioavailability (BA/ bioequivalence (BE studies are the cornerstone for the approval of generic drugs. While BA/BE assessment involving the pharmacokinetic data of the parent compound has been routinely performed, the introduction of the assessment of metabolite(s data, alone or in addition to parent compound, has also emerged. In this context, the assessment of BA/BE of metabolite(s may pose additional complexities and challenges, if the metabolic pathway is under the influence of a polymorphic enzyme. This communication provides brief perspectives on the challenges and study design considerations for the assessment of polymorphic metabolite in BA/BE studies.

  14. Study of Value Assessment Model of Forest Biodiversity Based on the Habitat Area in China

    OpenAIRE

    Ying Zhang; Hui Li; Ye Feng

    2014-01-01

    Forest biodiversity is an important part of biodiversity. There is an essential significance of studying forest biodiversity assessment for promoting the conservation of biodiversity and enhancing biodiversity management in China. This study collected forest biodiversity habitat area, output value of forestry and so on forest biodiversity assessment-related data from 2001 to 2010 in China and using optimal control methods in cybernetics to establish value assessment model of forest biodiversi...

  15. A Study on the Correlation between Second Language Learning Motiva-tion and Formative Assessment

    Institute of Scientific and Technical Information of China (English)

    何爱玲; 杨坚

    2014-01-01

    This paper explores the relationship between motivation and assessment and find out the assessment strategies which could motivate students better in L2 learning based on the data and responses collected from 30 non-English majors in a regional university. The data and responses revealed that formative assessment could motivate students better, especially during the process of English learning. It also revealed some problems existing in the assessment strategies implemented in this study, such as the im-partiality of peer-assessment and the poor efficiency of group work.

  16. A Psychometric Study of the Infant and Toddler Intervals of the Social Emotional Assessment Measure

    Science.gov (United States)

    Squires, Jane K.; Waddell, Misti L.; Clifford, Jantina R.; Funk, Kristin; Hoselton, Robert M.; Chen, Ching-I

    2013-01-01

    Psychometric and utility studies on Social Emotional Assessment Measure (SEAM), an innovative tool for assessing and monitoring social-emotional and behavioral development in infants and toddlers with disabilities, were conducted. The Infant and Toddler SEAM intervals were the study focus, using mixed methods, including item response theory…

  17. Assessing Medication Effects in the MTA Study Using Neuropsychological Outcomes

    Science.gov (United States)

    Epstein, Jeffery N.; Conners, C. Keith; Hervey, Aaron S.; Tonev, Simon T.; Arnold, L. Eugene; Abikoff, Howard B.; Elliott, Glen; Greenhill, Laurence L.; Hechtman, Lily; Hoagwood, Kimberly; Hinshaw, Stephen P.; Hoza, Betsy; Jensen, Peter S.; March, John S.; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen; Vitiello, Benedetto; Wigal, Timothy

    2006-01-01

    Background: While studies have increasingly investigated deficits in reaction time (RT) and RT variability in children with attention deficit/hyperactivity disorder (ADHD), few studies have examined the effects of stimulant medication on these important neuropsychological outcome measures. Methods: 316 children who participated in the Multimodal…

  18. Assessment of Confounding in Studies of Delay and Survival

    DEFF Research Database (Denmark)

    Tørring, Marie Louise; Vedsted, Peter; Frydenberg, Morten;

    Pathology Registry, and Statistics Denmark. Among other statistical methods the empirical study will involve use of sensitivity analysis. The statistical analyses will be performed using Stata 9. PERSPECTIVES: A systematic evaluation of confounding will improve our ability to interpret observational studies...

  19. Relations between student perceptions of assessment authenticity, study approaches and learning outcome.

    NARCIS (Netherlands)

    Gulikers, Judith; Bastiaens, Theo; Kirschner, Paul A.; Kester, Liesbeth

    2008-01-01

    Gulikers, J. T. M., Bastiaens, Th. J., Kirschner, P. A., & Kester, L. (2006). Relations between student perceptions of assessment authenticity, study approaches and learning outcome. Studies in Educational Evaluation, 32 , 381-400

  20. Assessment of human decision reliability - a case study

    International Nuclear Information System (INIS)

    In his discussion of this case study, the author indicates that human beings are not merely machines who use rules. Thus, more focus needs to be put on studying decision making situations and their contexts. Decision theory (both normative and descriptive) and contextual psychological approaches may offer tools to cope with operator decision making. Further an ideal decision space needs to be defined for operators. The case study specifically addressed a loss of feedwater scenario and the various operator decisions that were involved in that scenario. It was concluded from this particular study that there are significant differences in the crew decision behaviours that are not explained by process variables. Through use of evidence from simulator tests with expert judgement, an approach to estimate probabilities has been developed. The modelling approach presented in this discussion is an extension of current HRA paradigms, but a natural one since all human beings make decisions

  1. A social work study for assessment of entrepreneurs' personal characteristics

    Directory of Open Access Journals (Sweden)

    Ahmad Ahmadkhani

    2012-01-01

    Full Text Available The personality of an entrepreneur plays an important role on the success of creating new ideas. There are different characteristics such as courage, hardness, braveness, which could help an entrepreneur reach his/her goals. In this paper, we present an empirical study to learn more about students who are supposed to act as entrepreneur to create jobs in different fields of accounting, computer science, mechanical engineering, etc. In this paper, There are seven aspects of accepting reasonable risk, locus of control, the need for success, mental health conditions, being pragmatic, tolerating ambiguity, dreaming and the sense of challenging in our study to measure the level of entrepreneurship. We implement ANOVA test to measure different entrepreneurship characteristics of students who study in various educational fields. The case study is associated with Sama private university located in city of Zanjan/Iran. The results indicate that there are not meaningful differences among pairwise comparison of many engineering fields.

  2. Case Study: Visual Analytics in Software Product Assessments

    OpenAIRE

    Telea, Alexandru; Voinea, Lucian; Lanza, M.; Storey, M.; Muller, H

    2009-01-01

    We present how a combination of static source code analysis, repository analysis, and visualization techniques has been used to effectively get and communicate insight in the development and project management problems of a large industrial code base. This study is an example of how visual analytics can be effectively applied to answer maintenance questions and support decision making in the software industry. We comment on the relevant findings during the study both in terms of used techniqu...

  3. US country studies program: Support for climate change studies, national plans, and technology assessments

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This paper describes the objectives of the next phase of the U.S. Country Studies Program which was launched in support of the Framework Convention on Climate Change (FCCC). The next phases of this program aim to: assist countries in preparing Climate Change Action plans; support technology assessments and development of technology initiatives; enhance exchange of information and expertise in support of FCCC. The program offers support for these processes in the form of handbooks which have been published to aid in preparing action plans, and to provide information on methane, forestry, and energy technologies. In addition an array of training workshops have been and are scheduled to offer hands on instruction to participants, expert advice is available from trained personnel, and modeling tools are available to aid in development of action plans.

  4. Improving Biomarker Development and Assessment: Standards for Study Design

    Institute of Scientific and Technical Information of China (English)

    Ziding FENG

    2009-01-01

    Background: The Early Detection Research Network (EDRN), NCI funded and investigator driven, has the mission to evaluate biomarkers for their clinical utilities in cancer risk prediction, diagnosis, early detection, and prognosis. Abundant cancer biomarkers reported in literature yet few are used in clinics. Therefore, the emphasis of the EDRN is biomarker validation. Although schema for a phased approach to development exists and guidelines are available for study reporting, a coherent and comprehensive set of guideline for a definitive biomarker validation study design have not been delineated.Methods: We proposed PROBE study design, Prospective specimen collec-tion and Retrospective Blinded Evaluation, for pivotal definitive evaluation of the accuracy of a classification biomarker. A detailed formulation of all aspects of the design is provided. Four tables itemize aspects that relate to (i) the Clinical Context; (ii) Performance Criteria; (iii) the Biomarker test; and (iv) Study power and termination. Alternative designs and strategies were contrasted to illustrate the merit of PROBE design.Results: The ideas are applied to studies of biomarkers the intended use of which is for disease diagnosis, screening, or prognosis. Two EDRN valida-tion studies (breast cancer and prostate cancer) were used as examples to elucidate PROBE design.Conclusion: Common biases that pervade the biomarker research literaturewould be eliminated if these rigorous standards were followed closely. We urge the adoption of the design as standard of practice for pivotal evaluation of the classification accuracy ofbiomarkers.

  5. How to scientifically assess a restoration project: a case study

    Science.gov (United States)

    Alvarez de Buergo, M.; Fort, R.; Freire, D. M.; Lopez-Arce, P.; Vazquez-Calvo, C.

    2012-04-01

    Commonly, it is said that there is lack of communication among scientists, conservators, restorers, project managers and architects. But sometimes this communication flows, and we can find enormous benefits from and for all the participating agents. This is the case we present in this work, in which technical agents in charge of the restoration of a building, asked for some scientific advice to perform the restoration of a heritage building. The results were successful and fantastic for both of them, in terms of one part asking for consultation and the other answering to the demands and resolving real problems. This is the case of a marvellous Renaissance building (Medinaceli Dukes palace, 15th-16th centuries) in the central area of Spain (Cogolludo, Guadalajara). Focused on the restoration project, we were asked for consultancy on how to solve matters like the assessment of the already fixed in project cleaning method for the stone façades, the efficacy and durability methods for some conservation products to be applied, the presence or not of a patina on the stone; the viability of using some restoration mortars, and the origin of some efflorescences that came out just after placed in the building a restoration rendering mortar. Responses to these matters were answered by performing tests both in the lab and on site in the building. The efficiency and effects on stone of the blasting cleaning method was assessed by first analysing the nature and thickness of the surface deposits to be removed (SEM-EDS analyses); secondly, roughness and colour measurements were performed, and thirdly, SEM-EDS analyses were carried out again to determine whether the cleaning method was able to remove part of the surface deposits, completely, or even part of the stone substrate. Some conservation products were tested on stone specimens, both their efficacy and their durability, concluding that it was better not to apply any of them. A patina was found on the stone façade under SEM

  6. A comparative study of objective and subjective assessment of occupational risk.

    Science.gov (United States)

    Koradecka, Danuta; Pośniak, Małgorzata; Widerszal-Bazyl, Maria; Augusty Nska, Danuta; Radkiewicz, Piotr

    2010-01-01

    Measurement of dangerous, harmful and annoying factors in the working environment are used to assess occupational risk. Surveys on workers' subjective perception of risk are used, too. This study aimed to compare subjective assessment of work-related factors with their objective measurements and a national database on occupational risk. Spearman's correlation analysis, stepwise regression analysis and structural modelling were used to determine the relationship between subjective and objective risk assessment and to acquire knowledge about the role of psychosocial job characteristics as predictors of subjective assessment. Subjective assessment of hazards was related not only to their objective measurements but also to psychosocial job characteristics, workers' individual characteristics and work load. Even though subjective and objective assessments of hazard are strongly related, they are distinct phenomena. Hence, risk assessment should be carried out with both objective and subjective methods. PMID:20331915

  7. Evaluation on the Feasibility of Using Ultrasonic Testing of Reactor Pressure Vessel Welds for Assessing Flaw Density/Distribution per 10 CFR 50.61a, Alternate Fracture Toughness Requirements for Protection Against Pressurized Thermal Shock

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Edmund J.; Anderson, Michael T.

    2014-06-10

    This technical letter report provides the status of an assessment undertaken by PNNL at the request of the NRC to verify the capability of periodic ASME-required volumetric examinations of reactor vessels to characterize the density and distribution of flaws of interest for applying §50.61a on a plant-by-plant basis. The PTS rule, described in the Code of Federal Regulations, Title 10, Section 50.61 (§50.61), "Fracture Toughness Requirements for Protection against Pressurized Thermal Shock Events," establishes screening criteria to ensure that the potential for a reactor vessel to fail due to a PTS event is deemed to be acceptably low. Recently, the NRC completed a research program that concluded that the risk of through-wall cracking due to a PTS event is much lower than previously estimated. The NRC subsequently developed and promulgated an alternate PTS rule, §50.61a, that can be implemented by PWR licensees. The §50.61a rule differs from §50.61 in that it requires licensees who choose to follow this alternate method to analyze the results from periodic volumetric examinations required by the ASME Code, Section XI, Rules for Inservice Inspection (ISI) of Nuclear Power Plants.

  8. Assessing CSR and Applying Social Life Cycle Assessment: A case study on Biochemical Oxygen Demand Online Monitor

    OpenAIRE

    Wan, He

    2012-01-01

    Wuhan China and Borlänge Sweden collaborate to promote sustainable business growths. This thesis, being part of sustainable business project, aims to understand how business can contribute to sustainable development and explore mechanisms of social life cycle assessment. In an effort to answer research questions and further to achieve the general purpose, a BOD online monitor case study is described and analyzed by applying both qualitative and quantitative approaches. Data collection is base...

  9. Geothermal reservoir assessment case study: Northern Dixie Valley, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Denton, J.M.; Bell, E.J.; Jodry, R.L.

    1980-11-01

    Two 1500 foot temperature gradient holes and two deep exploratory wells were drilled and tested. Hydrologic-hydrochemical, shallow temperature survey, structural-tectonic, petrologic alteration, and solid-sample geochemistry studies were completed. Eighteen miles of high resolution reflection seismic data were gathered over the area. The study indicates that a geothermal regime with temperatures greater than 400/sup 0/F may exist at a depth of approximately 7500' to 10,000' over an area more than ten miles in length.

  10. Looking at the Mirror: A Self-Study of Science Teacher Educators' PCK for Teaching Teachers

    Science.gov (United States)

    Demirdögen, Betül; Aydin, Sevgi; Tarkin, Aysegül

    2015-01-01

    In this self-study, we aimed to delve into how re-designing and teaching re-designed practicum course offered to pre-service teachers (PTs) enriched our, as science teacher educators, development of pedagogical content knowledge (PCK) for teaching science teachers. This self-study was conducted during a compulsory practicum course in which we…

  11. Objective Measurements in Assessing a Black Music Course of Study.

    Science.gov (United States)

    Taylor, Frederick J.

    1990-01-01

    A study of 80 eighth grade students investigated whether incorporation of a African-American music program would have special benefits for African-American students, music-experienced students, or high-musical-ability students. African-American students, taught material consistent with their heritage, performed better than whites. It is concluded…

  12. Preliminary Systems Design Study assessment report. Volume 8, Appendixes

    Energy Technology Data Exchange (ETDEWEB)

    Mayberry, J.L.; Feizollahi, F.; Del Signore, J.C.

    1992-01-01

    The System Design Study (SDS), part of the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex`s Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each concept. This volume of the Systems Design Study contain four Appendixes that were part of the study. Appendix A is an EG&G Idaho, Inc., report that represents a review and compilation of previous reports describing the wastes and quantities disposed in the Subsurface Disposal Area of the Idaho National Engineering Laboratory. Appendix B contains the process flowsheets considered in this study, but not selected for detailed analysis. Appendix C is a historical tabulation of radioactive waste incinerators. Appendix D lists Department of Energy facilities where cementation stabilization systems have been used.

  13. Genesis Solar Wind Collector Cleaning Assessment: 60366 Sample Case Study

    Science.gov (United States)

    Goreva, Y. S.; Gonzalez, C. P.; Kuhlman, K. R.; Burnett, D. S.; Woolum, D.; Jurewicz, A. J.; Allton, J. H.; Rodriguez, M. C.; Burkett, P. J.

    2014-01-01

    In order to recognize, localize, characterize and remove particle and thin film surface contamination, a small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques [1-5]. Here we present preliminary results for sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C).

  14. Development of the gagging problem assessment : A pilot study

    NARCIS (Netherlands)

    van den Heuvell, G. F. E. C. van Linden; Ter Pelkwijk, B. J.; Stegenga, B.

    2008-01-01

    An accepted management strategy for gagging problems appears not to exist. A reliable and valid instrument is needed to develop an evidence based treatment for this clinical problem. The aim of this pilot study was to evaluate the reliability and validity of a newly developed measurement tool for de

  15. Case Study : Visual Analytics in Software Product Assessments

    NARCIS (Netherlands)

    Telea, Alexandru; Voinea, Lucian; Lanza, M; Storey, M; Muller, H

    2009-01-01

    We present how a combination of static source code analysis, repository analysis, and visualization techniques has been used to effectively get and communicate insight in the development and project management problems of a large industrial code base. This study is an example of how visual analytics

  16. MRI tracheomalacia (TM) assessment in pediatric patients: feasibility study

    DEFF Research Database (Denmark)

    Ciet, P.; Wielopolski, P.; Lever, S.;

    2011-01-01

    Purpose: TM is an excessive narrowing of the intrathoracic part of the trachea. TM is a common congenital pediatric anomaly, but it’s often not recognized due to its unspecific clinical presentation. The aims of our study are: 1) to develop cine-MRI sequences to visualize central airways in static...

  17. Assessment of vascular and endothelial dysfunction in nutritional studies.

    Science.gov (United States)

    Ray, S; Miglio, C; Eden, T; Del Rio, D

    2014-09-01

    Vascular and endothelial dysfunction (VED) is emerging as a potential set of early markers of cardiovascular disease risk and tests for its measurement have been widely used in clinical research. The aim of this viewpoint is to describe and discuss the current usage of these measures in well-designed nutritional trials, using the potential relationship between fruit juice intake and VED as example. A search was conducted using the NHS evidence portal including studies published in English between January 1980 and October 2013. Only 10 suitable studies were selected, which investigated the effect of fruit juice intake on VED, among which 4 interventions used flow-mediated dilatation, 2 arterial stiffness, 2 a combination of arterial stiffness and flow-mediated dilatation, 2 carotid intimal media thickness and 1 iontophoresis with laser Doppler. Despite minimal effects reported on classical CVD markers, such as lipids, 8 out of the 10 identified studies reported an effect on endothelial function following juice consumption, indicating that VED tests can be effectively used in human dietary interventions to identify relationships between bioactive compounds from fruit and CVD risk. However, paucity of available data, scarcity of compound bioavailability and metabolism information, strong heterogeneity among experimental methodologies and a number of limitations to study designs, still limit the interpretation of the results obtained through these measures. Future, well-designed studies with greater attention to consider use of VED measures are needed to strengthen the utility of VED tests in nutrition research such as those investigating the impact of polyphenol-rich juices and CVD risk.

  18. Teachers’ Beliefs about Young EFL Learners’ Self-assessment: a Case Study of Macedonia

    Directory of Open Access Journals (Sweden)

    /Anžela Nikolovska

    2015-11-01

    Full Text Available The paper explores Macedonian primary EFL teachers’ attitudes, beliefs and practices regarding self-assessment of young learners (10-12 year-olds. The study surveyed primary EFL teachers (n=30 who teach English to 5th and 6th graders. The results indicated that vocabulary, grammar and reading were more often the focus of self-assessment tasks than the other areas of language learning. This, along with the finding that the receptive language skills were more frequently self-assessed than the productive skills has been attributed to the impact of the external exam. The most frequently used self-assessment techniques were can-do statements and check-lists. The perceived benefits and challenges of self-assessment have been found to be compatible with the findings of other studies. In spite of their positive attitudes towards learner self-assessment, the teachers expressed awareness of certain problems underlying its implementation as well as uncertainty about how to train learners to self-assess. In line with the conclusions, recommendations have been made regarding the need for greater emphasis on self-assessment of the neglected language areas (speaking and writing, the necessity of using a variety of self-assessment formats and the need for learner training in self-assessment from an early age.

  19. Students' and teachers' perceptions of clinical assessment program: A qualitative study in a PBL curriculum

    Directory of Open Access Journals (Sweden)

    van der Vleuten Cees

    2009-12-01

    Full Text Available Abstract Background "Examinations drive students' learning." This statement refers to what is assumed to be one of the strongest relationships in education. We explored in this research how and why students differ in their approaches to learning, how assessment affects deep learning, and which barriers stand in the way of good assessment and learning in the clinical years of a Problem Based Learning (PBL graduate entry medical curriculum. Findings Method: We conducted a qualitative, phenomenological study using semi-structured group interviews with students and semi-structured individual interviews with teachers and students. The transcripts were analyzed, and themes were identified. Setting: The research was conducted at the King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia from November 2007 to March 2008. Results: A total of 28 students participated in 7 focus group interviews. Semi-structured individual interviews were conducted with 12 teachers and 12 students. The analysis yielded four themes: summative assessment, formative assessment, continuous assessment of clinical attachments, and learning objectives. Conclusions The results of this study confirm that assessment affects students' perceptions of learning and how they learn. These effects are not uniformly positive. According to the students, the predominantly summative assessment program offers little inducement to engage in deep learning. They express a clear preference for formative assessment, which may foster a deeper approach to learning. Efforts to achieve more clinically relevant assessment with adequate balance between the various types of assessment are required. Research is needed to decide this balance.

  20. An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study

    Energy Technology Data Exchange (ETDEWEB)

    Euling, Susan Y., E-mail: euling.susan@epa.gov [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Thompson, Chad M. [ToxStrategies, Inc., 23501 Cinco Ranch Blvd., Suite G265, Katy, TX 77494 (United States); Chiu, Weihsueh A. [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Benson, Robert [U.S. Environmental Protection Agency, Region 8, Mail code 8P-W, 1595 Wynkoop Street, Denver, CO 80202 (United States)

    2013-09-15

    An approach for evaluating and integrating genomic data in chemical risk assessment was developed based on the lessons learned from performing a case study for the chemical dibutyl phthalate. A case study prototype approach was first developed in accordance with EPA guidance and recommendations of the scientific community. Dibutyl phthalate (DBP) was selected for the case study exercise. The scoping phase of the dibutyl phthalate case study was conducted by considering the available DBP genomic data, taken together with the entire data set, for whether they could inform various risk assessment aspects, such as toxicodynamics, toxicokinetics, and dose–response. A description of weighing the available dibutyl phthalate data set for utility in risk assessment provides an example for considering genomic data for future chemical assessments. As a result of conducting the scoping process, two questions—Do the DBP toxicogenomic data inform 1) the mechanisms or modes of action?, and 2) the interspecies differences in toxicodynamics?—were selected to focus the case study exercise. Principles of the general approach include considering the genomics data in conjunction with all other data to determine their ability to inform the various qualitative and/or quantitative aspects of risk assessment, and evaluating the relationship between the available genomic and toxicity outcome data with respect to study comparability and phenotypic anchoring. Based on experience from the DBP case study, recommendations and a general approach for integrating genomic data in chemical assessment were developed to advance the broader effort to utilize 21st century data in risk assessment. - Highlights: • Performed DBP case study for integrating genomic data in risk assessment • Present approach for considering genomic data in chemical risk assessment • Present recommendations for use of genomic data in chemical risk assessment.

  1. A comparative study of pose representation and dynamics modelling for online motion quality assessment

    OpenAIRE

    Tao, Lili; Paiement, Adeline; Aldamen, Dima; Mirmehdi, Majid; Hannuna, Sion; Camplani, Massimo; Burghardt, Tilo; Craddock, Ian

    2016-01-01

    Quantitative assessment of the quality of motion is increasingly in demand byclinicians in healthcare and rehabilitation monitoring of patients. We study andcompare the performances of different pose representations and HMM models ofdynamics of movement for online quality assessment of human motion. In a general sense, our assessment framework builds a model of normal human motionfrom skeleton-based samples of healthy individuals. It encapsulates the dynamicsof human body pose using robust ma...

  2. Assessing Landscape Ecological Risk in a Mining City: A Case Study in Liaoyuan City, China

    OpenAIRE

    Jian Peng; Minli Zong; Yi'na Hu; Yanxu Liu; Jiansheng Wu

    2015-01-01

    Landscape ecological risk assessment can effectively identify key elements for landscape sustainability, which directly improves human wellbeing. However, previous research has tended to apply risk probability, measured by overlaying landscape metrics to evaluate risk, generally lacking a quantitative assessment of loss and uncertainty of risk. This study, taking Liaoyuan City as a case area, explores landscape ecological risk assessment associated with mining cities, based on probability of ...

  3. Deliberate self harm assessment by accident and emergency staff--an intervention study.

    OpenAIRE

    Crawford, M J; Turnbull, G; Wessely, S

    1998-01-01

    OBJECTIVE: To examine the impact of specific training for accident and emergency (A&E) staff on the quality of psychosocial assessment of deliberate self harm patients. METHODS: A non-randomised intervention study that compared the psychosocial assessment of deliberate self harm patients before and after a one hour teaching session for the A&E departments nursing and junior medical staff. Adequacy of psychosocial assessment was judged by examining A&E case notes. The records of the hospital's...

  4. Critical Analysis of Assessment Studies of the Animal Ethics Review Process †

    OpenAIRE

    Orsolya Varga

    2013-01-01

    Simple Summary In many countries, the approval of animal research projects depends on the decisions of the ethics committees which review the projects. Since the efficiency of the protection of experimental animals greatly depends on the performance of the ethics committees, its regular assessment is crucial. This paper reviews the results of studies assessing the performance of the ethics committees, and emphasizes the importance of outcome assessment in the evaluation of the performance of ...

  5. Study on Environmental Impact Assessment of Technological Transformation Project of X Corporation

    OpenAIRE

    Dianwei Qi; Xin Zhang

    2013-01-01

    China is the world first country to produce cement. It is necessary for concrete construction project to implement environmental impact assessment according to national legal requirements. Applying the theory of the environmental impact assessment and environmental impact laws and regulations ,based on engineering analysis and environmental status investigation and evaluation, the paper studies on environmental impact assessment about technological transformation project of X Corporation and ...

  6. Teacher Factors and Perceived Assessment Practices Needs of Social Studies Teachers in Cross River State, Nigeria

    Science.gov (United States)

    Ekuri, Emmanuel Etta; Egbai, Julius Michael; Ita, Caroline Iserome

    2011-01-01

    This study evaluated perceived assessment practices needs among social studies teachers in Cross River State, Nigeria, in relation to some teacher factors (attitude towards social studies, sex, teaching experience and educational qualification). Subjects who participated in this study were 297 social studies teachers (144 males and 153 females)…

  7. Assessing Statistical Change Indices in Selected Social Work Intervention Research Studies

    Science.gov (United States)

    Ham, Amanda D.; Huggins-Hoyt, Kimberly Y.; Pettus, Joelle

    2016-01-01

    Objectives: This study examined how evaluation and intervention research (IR) studies assessed statistical change to ascertain effectiveness. Methods: Studies from six core social work journals (2009-2013) were reviewed (N = 1,380). Fifty-two evaluation (n= 27) and intervention (n = 25) studies met the inclusion criteria. These studies were…

  8. A social work study for assessment of entrepreneurs' personal characteristics

    OpenAIRE

    Ahmad Ahmadkhani; Mehrnaz Paknezhad; Ahmad Maaroufkhani

    2012-01-01

    The personality of an entrepreneur plays an important role on the success of creating new ideas. There are different characteristics such as courage, hardness, braveness, which could help an entrepreneur reach his/her goals. In this paper, we present an empirical study to learn more about students who are supposed to act as entrepreneur to create jobs in different fields of accounting, computer science, mechanical engineering, etc. In this paper, There are seven aspects of accepting reasonabl...

  9. Continuous twice-a-day radiotherapy and concomitant CDDP-5FU chemotherapy (BiRCF) for the treatment of locally advanced inoperable pharyngeal carcinomas: final results of a multicentric phase II study (FNCLCC)

    International Nuclear Information System (INIS)

    Purpose: French 'Federation Nationale des Centres de Lutte Contre le Cancer' has initiated a phase II study in advanced pharynx cancer, to assess feasibility, local control at 6 months (mo), and control, survival and rate of distant metastases at 1 and 3 yr, obtained by a combined radio/chemotherapy regimen. Rationale was to associate, at full dose, most effective known treatments: (i) hyperfractionated continuous irradiation; and (ii) concurrent CDDP-5FU cycles. The inclusion of 30 to 35 cases was intended. Material and methods: Regardless of lymph nodes status, stage IV, not previously treated, unresectable carcinomas of oro- and hypopharynx were included. Eligibility criteria were KPS≥70, age≤65, acceptable renal, cardiac, and biological parameters. Patients (pts) were hospitalized during the overall treatment (trt) time (7 weeks), with enteral nutritional support and mucositis prevention. Supportive care included morphinomimetics and anti5HT3 antiemetics, without Colony Stimulating Factor. Radiotherapy (RT): Primary tumor and satellite nodes RT: 2 coaxial opposed lateral fields, 60Co γrays or 5-6 MV photons, 2 fractions (fr.) of 1.2 Gy/d., 5 days a week, without any interruption (D1->D46). Total tumor doses: 80.4 Gy/46 d. (oropharynx), 75.6 Gy/44 d. (hypopharynx). Spinal cord reduction at 40.8 Gy (complement with 7-10 MeV e-, 1 fr./d., 2 Gy/fr.). Supra-clavicular RT: 1 anterior field, 1 fr./d., 2 Gy/fr., total dose 50 Gy + e-. Chemotherapy consisted of CDDP: 100 mg/m2 (D1); 5FU: 750 mg/m2/d., continuous infusion (D2->D6). Pharmacokinetically guided 5FU dose adaptation was performed at D4. 2nd cycle at D22; 3rd at D43. Results: For 30 included pts (06/03/95), acute toxicity was acceptable, with grade 3 mucositis in 23 cases, grade 4 mucositis in 5 cases (1 to 4 d. of duration), grade 4 transient neutropenia and/or thrombocytopenia in 6 cases, with no significant disturbance in trt course, i.e. no break > 5 d. during RT. Dose of 5FU was reduced at 2nd cycle

  10. Epidemiological Assessments of Skin Outcomes in the Nurses’ Health Studies

    Science.gov (United States)

    Li, Wen-Qing; Cho, Eunyoung; Weinstock, Martin A.; Mashfiq, Hasan

    2016-01-01

    Objectives. To review the contribution of the Nurses’ Health Studies (NHSs) to identifying epidemiological factors associated with multiple skin diseases, including skin cancer, psoriasis, and other inflammatory and autoimmune skin diseases. Methods. We carried out a narrative review of NHS articles published between 1976 and 2016. Results. The NHSs have identified environmental and lifestyle factors related to psoriasis, supporting obesity and smoking as psoriasis risk factors; associations between psoriasis and diabetes, myocardial infarction, and Crohn’s disease, supporting psoriasis as a systemic disorder; and associations of pigmentary traits, ultraviolet radiation, and lifestyle factors such as citrus consumption with risk of skin cancer. Genetic studies have identified novel genetic loci for skin pigmentation (e.g., IRF4, SLC24A4, NID1, and EDNRB) and skin cancer (e.g., TET2 and HERC2-OCA2). Work continues on highly prevalent but less studied skin conditions such as rosacea, acne, and atopic dermatitis. The NHS results have influenced public health policies on indoor tanning devices. Conclusions. The NHSs have provided invaluable resources on skin disease population science and contributed to the etiological understanding of multiple skin disorders. PMID:27459457

  11. A Comparative Study on Emerging Electric Vehicle Technology Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Ford, Jonathan [Sentech, Inc.; Khowailed, Gannate [Sentech, Inc.; Blackburn, Julia [Sentech, Inc.; Sikes, Karen [Sentech, Inc.

    2011-03-01

    Numerous organizations have published reports in recent years that investigate the ever changing world of electric vehicle (EV) technologies and their potential effects on society. Specifically, projections have been made on greenhouse gas (GHG) emissions associated with these vehicles and how they compare to conventional vehicles or hybrid electric vehicles (HEVs). Similar projections have been made on the volumes of oil that these vehicles can displace by consuming large amounts of grid electricity instead of petroleum-based fuels. Finally, the projected rate that these new vehicle fleets will enter the market varies significantly among organizations. New ideas, technologies, and possibilities are introduced often, and projected values are likely to be refined as industry announcements continue to be made. As a result, over time, a multitude of projections for GHG emissions, oil displacement, and market penetration associated with various EV technologies has resulted in a wide range of possible future outcomes. This leaves the reader with two key questions: (1) Why does such a collective range in projected values exist in these reports? (2) What assumptions have the greatest impact on the outcomes presented in these reports? Since it is impractical for an average reader to review and interpret all the various vehicle technology reports published to date, Sentech Inc. and the Oak Ridge National Laboratory have conducted a comparative study to make these interpretations. The primary objective of this comparative study is to present a snapshot of all major projections made on GHG emissions, oil displacement, or market penetration rates of EV technologies. From the extensive data found in relevant publications, the key assumptions that drive each report's analysis are identified and 'apples-to-apples' comparisons between all major report conclusions are attempted. The general approach that was taken in this comparative study is comprised of six primary

  12. Study on Space Audit Assessment Criteria for Public Higher Education Institution in Malaysia: Space Capacity Assessment

    Directory of Open Access Journals (Sweden)

    Wan Hamdan Wan Samsul Zamani

    2016-01-01

    Full Text Available The aim of this study is to measure the capacity rate of learning space based on the as-built drawing provided by the institutions or if the as-built drawing is missing, the researcher have to prepare measured drawing as per actual on site. The learning space Capacity Index is developed by analyzing the space design in as-built drawing or measured drawing and the list of learning spaces available at the institution. The Capacity Index is classified according to the level of Usable Floor Area (UFA and Occupancy Load (OL according to learning space design capacity. The classification of Capacity Index is demonstrated through linguistic value and the color-coded key. From the said index, the institution can easily identify whether the existing learning space is currently best used or vice versa and standard space planning compliance in Malaysia Public Higher Education Institutions. The data will assist the management to clarify whether to maximize the use of existing space or to request for new learning space.

  13. FINAL REPORT ON THE AQUATIC MERCURY ASSESSMENT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, N

    2008-09-30

    In February 2000, the United States Environmental Protection Agency (EPA) Region 4 issued a proposed Total Maximum Daily Load (TMDL) for total mercury in the middle and lower Savannah River. The initial TMDL, which would have imposed a 1 ng/l mercury limit for discharges to the middle/lower Savannah River, was revised to 2.8 ng/l in the final TMDL released in February 2001. The TMDL was intended to protect people from the consumption of contaminated fish, which is the major route of mercury exposure to humans. The most bioaccumulative form of mercury is methylmercury, which is produced in aquatic environments by the action of microorganisms on inorganic mercury. Because of the environmental and economic significance of the mercury discharge limits that would have been imposed by the TMDL, the Savannah River Site (SRS) initiated several studies concerning: (1) mercury in SRS discharges, SRS streams and the Savannah River, (2) mercury bioaccumulation factors for Savannah River fish, (3) the use of clams to monitor the influence of mercury from tributary streams on biota in the Savannah River, and (4) mercury in rainwater falling on the SRS. The results of these studies are presented in detail in this report. The first study documented the occurrence, distribution and variation of total and methylmercury at SRS industrial outfalls, principal SRS streams and the Savannah River where it forms the border with the SRS. All of the analyses were performed using the EPA Method 1630/31 ultra low-level and contaminant-free techniques for measuring total and methylmercury. Total mercury at National Pollutant Discharge Elimination System (NPDES) outfalls ranged from 0.31-604 ng/l with a mean of 8.71 ng/l. Mercury-contaminated groundwater was the source for outfalls with significantly elevated mercury concentrations. Total mercury in SRS streams ranged from 0.95-15.7 ng/l. Mean total mercury levels in the streams varied from 2.39 ng/l in Pen Branch to 5.26 ng/l in Tims Branch

  14. Assessment of domestic water quality: case study, Beirut, Lebanon.

    Science.gov (United States)

    Korfali, Samira Ibrahim; Jurdi, Mey

    2007-12-01

    In urban cities, the environmental services are the responsibility of the public sector, where piped water supply is the norm for urban household. Likewise, in Beirut City (capital of Lebanon) official water authorities are the main supplier of domestic water through a network of piping system that leaks in many areas. Beirut City and its suburbs are overpopulated since it is the residence of 1/3 of the Lebanese citizens. Thus, Beirut suffers deficiency in meeting its water demand. Water rationing, as a remedial action, is firmly established since four decades by the Lebanese Water Authorities. Consumers resorted then to private wells to supplement their domestic water needs. Consequently, household water quality is influenced by external factors relating to well water characteristics and internal factors depending on the types of the pipes of the distribution network and cross connections to sewer pipes. These factors could result in chemical and microbial contamination of drinking water. The objective of this study is to investigate domestic water quality variation in Beirut City emerging form the aforementioned factors. The presented work encircles a typical case study of Beirut City (Ras Beirut). Results showed deterioration pattern in domestic water quality. The predicted metal species and scales within the water pipes of distribution network depended on water pH, hardness, sulfate, chloride, and iron. The corrosion of iron pipes mainly depended on Mg hardness.

  15. Reactor physics studies for assessment of tramp uranium methods

    International Nuclear Information System (INIS)

    This paper presents calculation studies towards validation of a methodology for estimations of the tramp uranium mass from water chemistry measurements. Particular emphasis is given to verify, from a reactor physics point of view, the justification basis for the so-called 'Pu-based model' versus the 'U-based model' as a key assumption for the methodology. The computational studies are carried out for a typical BWR fuel assembly with CASMO-5M and MCNPX. By approximating the evolution of fissile nuclides and the fraction of 235U fissions to total fissions in different zones of a fuel rod, including tramp uranium on the clad surface, it is found that Pu gives the dominant contribution to fissions for tramp uranium after an irradiation on the outer clad surface of at least one cycle in a BWR. Thus, the use of the so-called Pu model for the determination of the tramp uranium mass (this means in particular using the yields for 239Pu fission) appears justified in the cases considered. On that basis, replacing the older U model by a Pu model is recommended. (authors)

  16. Reactor physics studies for assessment of tramp uranium methods

    Energy Technology Data Exchange (ETDEWEB)

    Grimm, P.; Vasiliev, A.; Wieselquist, W.; Ferroukhi, H. [Paul Scherrer Institut, CH 5232 Villigen (Switzerland); Ledergerber, G. [Kernkraftwerk Leibstadt AG, CH 5325 Leibstadt (Switzerland)

    2012-07-01

    This paper presents calculation studies towards validation of a methodology for estimations of the tramp uranium mass from water chemistry measurements. Particular emphasis is given to verify, from a reactor physics point of view, the justification basis for the so-called 'Pu-based model' versus the 'U-based model' as a key assumption for the methodology. The computational studies are carried out for a typical BWR fuel assembly with CASMO-5M and MCNPX. By approximating the evolution of fissile nuclides and the fraction of {sup 235}U fissions to total fissions in different zones of a fuel rod, including tramp uranium on the clad surface, it is found that Pu gives the dominant contribution to fissions for tramp uranium after an irradiation on the outer clad surface of at least one cycle in a BWR. Thus, the use of the so-called Pu model for the determination of the tramp uranium mass (this means in particular using the yields for {sup 239}Pu fission) appears justified in the cases considered. On that basis, replacing the older U model by a Pu model is recommended. (authors)

  17. Environmental Assessment of a Waste Incineration Tax. Case Study and Evaluation of a Framework for Strategic Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerklund, Anna; Johansson, Jessica [Swedish Defence Research Agency, Stockholm (Sweden); Nilsson, Maans [Stockholm Environment Inst., Stockholm (Sweden); Eldh, Peter; Finnveden, Goeran [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Industrial Ecology

    2003-12-01

    A framework for Strategic Environmental Assessment (SEA) is tested in a case study on a proposed waste incineration tax. Also included is testing of developed methods for valuation and site-dependent life cycle impact assessment. The results indicate that although a suggested waste incineration tax of 400 SEK/ton is likely to lead to environmental improvements, these are small compared to the potential improvements as shown in more visionary scenarios. In order to go in this direction a waste incineration tax based on the content of fossil carbon in the waste would be useful. The framework for SEA includes several different pathways. These have different advantages and disadvantages and provide different types of information. It is therefore suggested that they largely complement each other and that the choice of methods should be done in relation to the function of the SEA and the questions asked.

  18. Environmental Assessment of a Waste Incineration Tax. Case Study and Evaluation of a Framework for Strategic Environmental Assessment

    International Nuclear Information System (INIS)

    A framework for Strategic Environmental Assessment (SEA) is tested in a case study on a proposed waste incineration tax. Also included is testing of developed methods for valuation and site-dependent life cycle impact assessment. The results indicate that although a suggested waste incineration tax of 400 SEK/ton is likely to lead to environmental improvements, these are small compared to the potential improvements as shown in more visionary scenarios. In order to go in this direction a waste incineration tax based on the content of fossil carbon in the waste would be useful. The framework for SEA includes several different pathways. These have different advantages and disadvantages and provide different types of information. It is therefore suggested that they largely complement each other and that the choice of methods should be done in relation to the function of the SEA and the questions asked.

  19. The Relationship between Studying Music and Mathematics Performance on the New Jersey High School Proficiency Assessment

    Science.gov (United States)

    Prokop, Kristie L.

    2011-01-01

    On assessments such as Trends in International Mathematics and Science Study (TIMSS) (Stigler & Hiebert, 1999) and Program for International Assessment (PISA) ("PISA 2006 Science Competencies for Tomorrow's World", 2007) students in the United States have not been performing as well in mathematics as students in other countries. In order for the…

  20. Assessing Researcher Interdisciplinarity: A Case Study of the University of Hawaii NASA Astrobiology Institute

    OpenAIRE

    Gowanlock, Michael G.; Gazan, Rich

    2012-01-01

    In this study, we combine bibliometric techniques with a machine learning algorithm, the sequential Information Bottleneck, to assess the interdisciplinarity of research produced by the University of Hawaii NASA Astrobiology Institute (UHNAI). In particular, we cluster abstract data to evaluate Thomson Reuters Web of Knowledge subject categories as descriptive labels for astrobiology documents, assess individual researcher interdisciplinarity, and determine where collaboration opportunities m...

  1. How to assess common somatic symptoms in large-scale studies : A systematic review of questionnaires

    NARCIS (Netherlands)

    Zijlema, Wilma L.; Stolk, Ronald P.; Loewe, Bernd; Rief, Winfried; White, Peter D.; Rosmalen, Judith G. M.

    2013-01-01

    Objective: Many questionnaires for assessment of common somatic symptoms or functional somatic symptoms are available and their use differs greatly among studies. The prevalence and incidence of symptoms are partially determined by the methods used to assess them. As a result, comparison across stud

  2. Values as a Bridge between Sustainability and Institutional Assessment: A Case Study from BOKU University

    Science.gov (United States)

    Ribeiro, Maria Miguel; Hoover, Elona; Burford, Gemma; Buchebner, Julia; Lindenthal, Thomas

    2016-01-01

    Purpose: The purpose of this paper is to illustrate that values-focused assessment can provide a useful lens for integrating sustainability and institutional performance assessment in universities. Design/methodology/approach: This study applies a values elicitation methodology for indicator development, through thematic analysis of…

  3. Designing and Developing a Programme-Focused Assessment Strategy: A Case Study

    Science.gov (United States)

    Brunton, James; Brown, Mark; Costello, Eamon; Walsh, Elaine

    2016-01-01

    This case study describes the process that the Humanities Programme Team, in Dublin City University's Open Education Unit, has undertaken with regard to developing a systematic, programme-focused assessment strategy. It charts the development of an Assessment Matrix that facilitated the enhancement of programme coherence in the context of a…

  4. THE USE OF STEM CELLS FOR TOXICOLOGY STUDIES AND RISK ASSESSMENTS

    Science.gov (United States)

    In general terms, toxicology studies are used in support of risk assessments of adverse health outcomes as a result of exposures to chemical and physical agents. In particular, toxicological data are used to provide information that aids in the assessment of disease outcomes at e...

  5. Assessing Long-Term Effects of Inquiry-Based Learning: A Case Study from College Mathematics

    Science.gov (United States)

    Kogan, Marina; Laursen, Sandra L.

    2014-01-01

    As student-centered approaches to teaching and learning are more widely applied, researchers must assess the outcomes of these interventions across a range of courses and institutions. As an example of such assessment, this study examined the impact of inquiry-based learning (IBL) in college mathematics on undergraduates' subsequent grades…

  6. Health Literacy Assessment of the STOFHLA: Paper versus Electronic Administration Continuation Study

    Science.gov (United States)

    Chesser, Amy K.; Keene Woods, Nikki; Wipperman, Jennifer; Wilson, Rachel; Dong, Frank

    2014-01-01

    Low health literacy is associated with poor health outcomes. Research is needed to understand the mechanisms and pathways of its effects. Computer-based assessment tools may improve efficiency and cost-effectiveness of health literacy research. The objective of this preliminary study was to assess if administration of the Short Test of Functional…

  7. Changes and Possibilities: A Case Study of Nova Scotia Classroom Assessment Policies

    Science.gov (United States)

    Van Zoost, Steven

    2011-01-01

    Although numerous writers have identified a different set of skills needed for employment in New Times, little analytic attention has been paid to how educational assessment policies contribute to envisioning such future citizens. This case study illustrates how Nova Scotia classroom assessment policy for Grades 7-9 English classes envisions young…

  8. Information Literacy and Communication Research: A Case Study on Interdisciplinary Assessment

    Science.gov (United States)

    Natalle, Elizabeth J.; Crowe, Kathryn M.

    2013-01-01

    This report offers an interdisciplinary approach for conducting assessment on learning outcomes in undergraduate communication research skills where information literacy is embedded in the expected outcome. A Communication Studies department and the University Library piloted a two-year program to develop strategies for coordinated assessment that…

  9. Assessment of Visuospatial Neglect in Stroke Patients Using Virtual Reality: A Pilot Study

    Science.gov (United States)

    Jannink, Michiel J. A.; Aznar, Miguel; de Kort, Alexander Cornelis; van de Vis, Wim; Veltink, Peter; van der Kooij, Herman

    2009-01-01

    One of the neuropsychological deficits that can result from a stroke is the neglect phenomenon. Neglect has traditionally been assessed with paper-and-pencil tasks, which are administered within the reaching space of a person. The purpose of this explorative study is to investigate whether it is possible to assess neglect in the extrapersonal…

  10. Study of the Gastric Emptying in Humans: Biomagnetic Assessments

    Science.gov (United States)

    Hernández, E.; Córdova, T.; Huerta-Franco, R.; Sosa, M.; Vargas-Luna, M.

    2006-09-01

    Biomagnetic studies of the gastrointestinal system can be carried out in two ways. Recording the magnetic field produced by the myenteric nervous system or created by any oral contrast mean as magnetic tracers or markers. In the first case, a SQUID magnetometer is demanded while a fluxgate magnetometer is enough in the second case. In this work, a magnetic marker was ingested by 8 healthy volunteers, in three gastric volume conditions, to measure the luminal content volume effect in the gastric emptying and to perform the quantification of the peristaltic frequencies in gastric and duodenum tract segments. The average emptying times for low luminal content, relative to the emptying time when the intake was the highest, were 43.6 ± 15.6 % and 77.3 ± 47.0 %. These results show that the biomagnetic technique is a powerful modality to estimate the effects of the gastric volume in the gastric emptying and a way to record the peristaltic frequencies.

  11. Preliminary systems design study assessment report. Volume 7, Subsystem concepts

    Energy Technology Data Exchange (ETDEWEB)

    Mayberry, J.L.; Feizollahi, F.; Del Signore, J.C.

    1992-01-01

    The System Design Study (SDS), part of the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examined techniques available for the remediation of hazardous and transuranic waste stored at the Radioactive Waste Management Complex`s Subsurface Disposal Area at the INEL. Using specific technologies, system concepts for treating the buried waste and the surrounding contaminated soil were evaluated. Evaluation included implementability, effectiveness, and cost. The SDS resulted in the development of technology requirements including demonstration, testing, and evaluation activities needed for implementing each. This volume contains the descriptions and other relevant information of the four subsystems required for most of the ex situ processing systems. This volume covers the metal decontamination and sizing subsystem, soils processing subsystem, low-level waste subsystem, and retrieval subsystem.

  12. Feasibility studies of safety assessment methods for programmable automation systems. Final report of the AVV project

    International Nuclear Information System (INIS)

    Feasibility studies of two different groups of methodologies for safety assessment of programmable automation systems has been executed at the Technical Research Centre of Finland (VTT). The studies concerned the dynamic testing methods and the fault tree (FT) and failure mode and effects analysis (FMEA) methods. In order to get real experience in the application of these methods, an experimental testing of two realistic pilot systems were executed and a FT/FMEA analysis of a programmable safety function accomplished. The purpose of the studies was not to assess the object systems, but to get experience in the application of methods and assess their potentials and development needs. (46 refs., 21 figs.)

  13. Robot-assisted home hazard assessment for fall prevention: a feasibility study.

    Science.gov (United States)

    Sadasivam, Rajani S; Luger, Tana M; Coley, Heather L; Taylor, Benjamin B; Padir, Taskin; Ritchie, Christine S; Houston, Thomas K

    2014-01-01

    We examined the feasibility of using a remotely manoeuverable robot to make home hazard assessments for fall prevention. We employed use-case simulations to compare robot assessments with in-person assessments. We screened the homes of nine elderly patients (aged 65 years or more) for fall risks using the HEROS screening assessment. We also assessed the participants' perspectives of the remotely-operated robot in a survey. The nine patients had a median Short Blessed Test score of 8 (interquartile range, IQR 2-20) and a median Life-Space Assessment score of 46 (IQR 27-75). Compared to the in-person assessment (mean = 4.2 hazards identified per participant), significantly more home hazards were perceived in the robot video assessment (mean = 7.0). Only two checklist items (adequate bedroom lighting and a clear path from bed to bathroom) had more than 60% agreement between in-person and robot video assessment. Participants were enthusiastic about the robot and did not think it violated their privacy. The study found little agreement between the in-person and robot video hazard assessments. However, it identified several research questions about how to best use remotely-operated robots. PMID:24352900

  14. Varfarin in the complex treatment of antiphospholipid syndrome: preliminary results

    Directory of Open Access Journals (Sweden)

    T M Reshetnyak

    2003-01-01

    Full Text Available Objective. To assess efficacy and tolerance of varfarin in prophylaxis and therapy of thrombotic complications in patients with antiphospholipid syndrome (APS. Methods. 20 pts with APS (5 male and 15 female received varfarin during a year. 8 of them had primary APS (PAPS and 12 -systemic lupus erythematosus with APS (SLE+APS. 2 other pts (I with SLE+APS and I with PAPS received varfarin during the last 4 years. Nobody from 9 pts with PAPS received corticosteroids (CS. In SLE+APS pts CS dose varied from 4 to 20 mg/day and was not increased during follow up. During the study prothrombine time (PT was examined with thromboplastin ( manufactured by Renam having international sensitivity index 1,2 and international normalization relation (INR. Depending on treatment scheme APS pts were divided into 3 groups. Group 1 included 8 pts with INR<2,0, Group 2-7 with INR >3,0, group 3 - 7 pts with INR<2,0 receiving as additional treatment thrombo ASS 100 mg/day and vasonit from 600 to 1200 mg/day. Results. Two pts with INR = 1,8 had thrombosis recurrence (due to leg thrombophlebitis. There were no recurrences in other groups. 2 from 22 pts had "large" bleedings. "Small" bleedings episodes were noted in 7 from 22 pts. Largely that were subcutaneous bleedings (in 4 pts no more than 5 cm of size. Two pts receiving varfarin with INR 1,8 and 2,4 had renal colic. Conclusion. Our preliminary results prove the necessity of inclusion of varfarin in the treatment of pts with APS and thrombosis but intensive anticoagulant effect is not always desired.

  15. Assessment and seasonal variations of communicable diseases: 3 year study

    Directory of Open Access Journals (Sweden)

    D. Kalyani

    2016-04-01

    Results: Results showed that a total of 34,981 had been treated at the inpatient departments from the year 2011 to 2013. It was observed that communicable diseases constituted about 85% (30,082 of the total disease burden with viral infections being the commonest. Most of the diseases were observed to have a seasonal variation. The most common disease identified was viral fever 8713 (28.96%, secondly acute diarrheal diseases 7965(26.52% followed by enteric fever 2958 (9.83% and malaria 2443(8.12%. The least common were Rabies 80 (0.26 % and pertussis 37 (0.12%. Outbreaks of Measles and Diphtheria were also noted in this study. Conclusions: Many diseases have a seasonal variation and the burden of these diseases could be reduced if we device measures to detect the changes in their trend through the implementation of surveillance programs. The knowledge of the burden of these would also assist the health administrators in allocation of the resources. [Int J Res Med Sci 2016; 4(4.000: 1186-1192

  16. Isotope studies to assess water development in mining dump sites

    International Nuclear Information System (INIS)

    After the ending of the lignite exploitation open mining pits with dump sites of heterogeneous mixture of Tertiary and Quaternary sediments were flooded by groundwater and river water inflow forming partially acidic (pH about 2 to 3) mining lakes with high sulphate (>3000 mg/L) and iron content (>500 mg/L) (Friese et al., 1998). The renewing of the groundwater system in mining areas is a very complicated process. The knowledge of the whole as well as of parts of that process is important for the future water management and for land use. Acidification of surface and groundwater based on pyrite oxidation dominates water quality development of the groundwater and of the flooded pits. The different sulphur compounds and the distribution of sulphur sources (pyrite, sulphate, sulphide) can easily controlled by the sulphur and oxygen isotope analyses. Our studies are focused on an acidic mine lake ML 111 in the Lusatian Lignite District and on the Cospuden lignite mine south of Leipzig

  17. COMPARATIVE STUDY ON MAIN SOLVENCY ASSESSMENT MODELS FOR INSURANCE FIELD

    Directory of Open Access Journals (Sweden)

    Daniela Nicoleta SAHLIAN

    2015-07-01

    Full Text Available During the recent financial crisis of insurance domain, there were imposed new aspects that have to be taken into account concerning the risks management and surveillance activity. The insurance societies could develop internal models in order to determine the minimum capital requirement imposed by the new regulations that are to be adopted on 1 January 2016. In this respect, the purpose of this research paper is to offer a real presentation and comparing with the main solvency regulation systems used worldwide, the accent being on their common characteristics and current tendencies. Thereby, we would like to offer a better understanding of the similarities and differences between the existent solvency regimes in order to develop the best regime of solvency for Romania within the Solvency II project. The study will show that there are clear differences between the existent Solvency I regime and the new approaches based on risk and will also point out the fact that even the key principles supporting the new solvency regimes are convergent, there are a lot of approaches for the application of these principles. In this context, the question we would try to find the answer is "how could the global solvency models be useful for the financial surveillance authority of Romania for the implementation of general model and for the development of internal solvency models according to the requirements of Solvency II" and "which would be the requirements for the implementation of this type of approach?". This thing makes the analysis of solvency models an interesting exercise.

  18. Root Cause Assessment for a Manufacturing Industry: A Case Study

    Directory of Open Access Journals (Sweden)

    R. Kalantri

    2013-03-01

    Full Text Available Root-cause identification for quality related problems are key issues for manufacturing processes. It has been a very challenging engineering problem particularly in a multistage manufacturing, where maximum number of processes and activities are performed. However, it may also be implemented with ease in each and every individual set up and activities in any manufacturing process. Kaizen is aimed towards reduction in different types of losses i.e. Failure Loss/ Breakdown Loss, Minor stoppage, idling loss, Setup and adjustment loss etc. So as to improve quality and productivity.In this report, root-cause identification methodology has been adopted to eliminate the rejection of product manufactured by the enterprise and improving the life of product. Brainstorming and other Root Cause Assesmenttools have been used to find out the reasons of tube failure and vibration in tubular strander. Solutions of these problems have also given in this report. Kaizen activities have reduced the time consumed in daily activities of cleaning, lubricating, inspection etc. A detailed study has illustrated the effectiveness of the proposed methodology.

  19. Aspects of brittle failure assessment for RPV

    Energy Technology Data Exchange (ETDEWEB)

    Zecha, H.; Hermann, T.; Hienstorfer, W. [TUeV SUeD Energietechnik GmbH Baden-Wuerttemberg, Filderstadt (Germany); Schuler, X. [Materialpruefungsanstalt, Univ. Stuttgart (Germany)

    2009-07-01

    This paper describes the process of pressurized thermal shock analysis (PTS) and brittle failure assessment for the reactor pressure vessel (RPV) of the nuclear power plants NECKAR I/II. The thermo-hydraulic part of the assessment provides the boundary conditions for the fracture mechanics analysis. In addition to the one dimensional thermo-hydraulic simulations CFD, analyses were carried out for selected transients. An extensive evaluation of material properties is necessary to provide the input data for a reliable fracture mechanics assessment. For the core weld and the flange weld it has shown that brittle crack initiation can be precluded for all considered load cases. For the cold and hot leg nozzle detailed linear-elastic and elasticplastic Finite Element Analyses (FEA) are performed to verify the integrity of the RPV. (orig.)

  20. Assessing atmospheric temperature data sets for climate studies

    Directory of Open Access Journals (Sweden)

    Magnus Cederlöf

    2016-07-01

    Full Text Available Observed near-surface temperature trends during the period 1979–2014 show large differences between land and ocean, with positive values over land (0.25–0.27 °C/decade that are significantly larger than over the ocean (0.06–0.12 °C/decade. Temperature trends in the mid-troposphere of 0.08-0.11 °C/decade, on the other hand, are similar for both land and ocean and agree closely with the ocean surface temperature trend. The lapse rate is consequently systematically larger over land than over the ocean and also shows a positive trend in most land areas. This is puzzling as a response to external warming, such as from increasing greenhouse gases, is broadly the same throughout the troposphere. The reduced tropospheric warming trend over land suggests a weaker vertical temperature coupling indicating that some of the processes in the planetary boundary layer such as inversions have a limited influence on the temperature of the free atmosphere. Alternatively, the temperature of the free atmosphere is influenced by advection of colder tropospheric air from the oceans. It is therefore suggested to use either the more robust tropospheric temperature or ocean surface temperature in studies of climate sensitivity. We also conclude that the European Centre for Medium-Range Weather Forecasts Reanalysis Interim can be used to obtain consistent temperature trends through the depth of the atmosphere, as they are consistent both with near-surface temperature trends and atmospheric temperature trends obtained from microwave sounding sensors.

  1. Self-assessment and students' study strategies in a community of clinical practice: a qualitative study.

    NARCIS (Netherlands)

    Al-Kadri, H.M.; Al-Moamary, M.S.; Al-Takroni, H.; Roberts, C.; Vleuten, C.P.M. van der

    2012-01-01

    BACKGROUND: Self-assessment is recognized as a necessary skill for lifelong learning. It is widely reported to offer numerous advantages to the learner. The research evaluated the impact of students' and supervisors' self-assessment and feedback training on students' perceptions and practices of sel

  2. Assessment

    Directory of Open Access Journals (Sweden)

    D.F. Cortés-Rojas

    2016-07-01

    Full Text Available Spray drying has been successfully employed for the encapsulation of herbal bioactive compounds resulting in stable phytopharmaceutical preparations. Bidens pilosa L. is a South American medicinal plant with proved antimalaric, hepatoprotector and antioxidant activities, generally linked to their secondary metabolites, flavonoids and polyacetylenes. In this work the physicochemical stability of an optimized spray dried composition from a B. pilosa extract was evaluated at three different stress storage conditions in open containers and in sealed sachets. High performance liquid chromatography was employed to monitor the concentration of three marker compounds over 12 months. Color variation of the stored samples was evaluated by using a color spectrophotometer. It was observed that the concentration of the monitored compounds of the plant decreases more drastically in samples stored in open containers. The two flavonoids monitored, rutin and hyperoside, showed lower degradation than the polyacetylene. The concentration of the markers did not change significantly at the lowest temperature. With regard to color, darker hues were observed at higher temperatures and storage times. This study showed that the storage conditions cause significant impact on stability of standardized spray dried B. pilosa extract.

  3. Assessment of Social Media Utilization and Study Habit of Students of Tertiary Institutions in Katsina State

    Science.gov (United States)

    Olutola, Adekunle Thomas; Olatoye, Olufunke Omotoke; Olatoye, Rafiu Ademola

    2016-01-01

    This study investigated assessment of social media utilization and study habits of students of tertiary institutions in Katsina State. The descriptive survey design was adopted for this study. Three hundred and eighty-one (381) students' of tertiary institutions in Katsina State were randomly selected for the study. Researchers'-designed…

  4. Assessment of subtalar joint neutral position:a cadaveric study

    Institute of Scientific and Technical Information of China (English)

    CHEN Yan-xi; YU Guang-rong; MEI Jiong; ZHOU Jia-qian; WANG Wen

    2008-01-01

    Background Subtalar joint(STJ)neutral position is the position typically used by clinicians to obtain a cast representation of a patient's foot before fabrication of biomechanical functional orthosis. But no method for measuring STJ neutral position has been proven accurate and reproducible by different testers. This study was conducted to investigate the STJ neutral position in normal feet in cadavers. Methods Twelve fresh-frozen specimens of amputated lower legs were used. Pressure-sensitive films were inserted into the anterior and posterior articulation of STJ. The contact areas for various foot positions and under axial loads of 600 N were determined based on the gray level of the digitized film. The STJ neutral positions were determined as the ankle-foot position where the maxlmum contact area was achieved, because the neutral position of a joint was defined as the position where the concave and convex surfaces were completely congruous. Results In ankle-foot neutral position, the contact area of STJ was(2.79±0.24)cm2. In the range of motion of adduction-abduction (ADD-ABD), the maximum contact area was(3.00±0.26)cm2 when the foot was positioned 10°of ABD (F=221.361, P<0.05). In the range of motion of dorsiflexion-plantarflexion (DF-PF), the maximum contact area was (3. 61±0. 25)cm2 when the foot was positioned 20°of DF(F=121.067, P<0.05). In the range of motion of inversion-eversion (INV-EV), the maximum contact area was(3. 14+0.26)cm2 when the foot was positioned 10°of EV(F=256. 252, P<0.05). Conclusions Joints, such as STJ, therefore, are not necessarily in neutral position when the ankle. foot is placed in the traditional concept of neutral position. The results demonstrate that the most approximate STJ neutral position was in the foot position of 10°of abduction, 20°of dorsiflexion and 10°of eversion.

  5. Risk assessment after coronary angioplasty with SPECT myocardial perfusion studies

    International Nuclear Information System (INIS)

    The chest pain can be use for stratifying the risk of the patients after coronary angioplasty. Nevertheless this strategy has shown to have a low accuracy in the detection of restenosis and myocardial ischemia. Aims: To establish the usefulness of the SPECT studies in the risk stratification after the coronary angioplasty. Evaluate the incidence of silent ischemia or symptomatic, and its impact on the prognosis. Method: There were included 107 patients (p) submitted to a gated SPECT between the year of the coronary angioplasty. The analysis of the images was performed according to different scores (SSS, SRS, SDS). These data was correlated with the symptoms of the patients. We define group 1 (G1) as the asymptomatic without ischemia (n 59p), group 2 (G2) as silent ischemia (n = 28p) and group 3 (G3) as symptomatic with ischemia (n = 20p). A clinical follow-up was done in search of events (target vessel revascularization, unstable angina, AMI and death). Results: Significant differences were not observed in the clinical variables between the different groups. The SSS was lower in the G1 compare with G2 and G3 (p 0.0001) and was similar between the last two, p = NS (SSS: G1: 2.2 ± 4.9; G2: 7.6 ± 5.9; G3: 9.5 ± 6.8). The SDS was greater in G3 vs. G1 and G2, p = 0.0001, and greater in G2 vs. G1, p = 0.0001 (SDS: G1: 0; G2: 4.8 ± 3.5; G3: 7.2 ± 6.5). No differences where observed in the SRS between the three groups. In the follow-up the total percentage of events was lesser when compare the G1 with the G2 and G3 (G1: 3.3%; G2 and G3: 18.7%; p 0.02). The percentage of annual events of the G3 symptomatic with ischemia (11.03%) and G2 silent ischemia (4.04%) did not present differences (p 0.7). When the events of the G2 (4.04%) were compared with the G1 (1.24%) we observed a trend to major frequency of events in the G2 (p = 0.6). Conclusions: The presence of myocardial ischemia after coronary angioplasty is a determinant of the prognosis. Nevertheless, the extension

  6. Understanding Authentic Assessment in a Secondary Agricultural Mechanics Laboratory: An Instrumental Case Study

    Directory of Open Access Journals (Sweden)

    J. Joey Blackburn

    2013-06-01

    Full Text Available The instrumental case study reported here adds to the literature on authentic assessment by illuminating how one secondary agricultural education instructor employed authentic assessment in the agricultural mechanics laboratory. The study was underpinned by the constructivist notion of authentic learning and assessment, or allowing students to perform what they can do. Multiple sources of data regarding assessment practices were collected from an exemplary secondary agricultural mechanics instructor who demonstrated model authentic assessment behavior by (1 setting high and fair expectations for students, (2 establishing a progressive hierarchy of skills for students to master, (3 providing continuous feedback so that students had knowledge of their progress, and (4 being committed deeply to students’ success. The four themes resonated with previous literature and provided the foundation for a pragmatic model of authentic assessment in the secondary agricultural mechanics laboratory. Future research should focus on refining the model of authentic assessment in agricultural mechanics for a larger audience, as case studies are limited in their ability to generalize. Additionally, research should be conducted to determine how authentic assessment impacts student performance on Oklahoma Agricultural Power and Technology competency examinations.

  7. The effect of practical experience on perceptions of assessment authenticity, study appraoch, and learning outcome.

    NARCIS (Netherlands)

    Gulikers, Judith; Kester, Liesbeth; Kirschner, Paul A.; Bastiaens, Theo

    2008-01-01

    Gulikers, J. T. M., Kester, L., Kirschner, P. A., & Bastiaens, Th. J. (2008). The effect of practical experience on perceptions of assessment authenticity, study appraoch, and learning outcome. Learning and Instruction, 18, 172-186.

  8. Prospective Assessment of Cannabis Withdrawal in Adolescents with Cannabis Dependence: A Pilot Study

    Science.gov (United States)

    Milin, Robert; Manion, Ian; Dare, Glenda; Walker, Selena

    2008-01-01

    A study to identify and assess the withdrawal symptoms in adolescents afflicted with cannabis dependence is conducted. Results conclude that withdrawal symptoms of cannabis were present in adolescents seeking treatment for this substance abuse.

  9. INFLUENCE OF EXPOSURE ASSESSMENT METHOD IN AN EPIDEMIOLOGIC STUDY OF TRIHALOMETHANE EXPOSURE AND SPONTANEOUS ABORTION

    Science.gov (United States)

    Trihalomethanes are common contaminants of chlorinated drinking water. Studies of their health effects have been hampered by exposure misclassification, due in part to limitations inherent in using utility sampling records. We used two exposure assessment methods, one based on ut...

  10. Quality Assessment Study of Brief Psychotherapy at a University HMO Setting.

    Science.gov (United States)

    Poey, Kent

    1981-01-01

    The results of a short-term psychotherapy quality assessment study, conducted at a university mental health service, are described. The outcome indicates that high-quality brief psychotherapy can be provided by university counseling services. (JN)

  11. Hegemonic Masculinity in Sport Education: Case Studies of Experienced In-Service Teachers with Teaching Orientations

    Science.gov (United States)

    Chen, YuChun; Curtner-Smith, Matthew

    2013-01-01

    Research has revealed that while pre-service teachers (PTs) with coaching orientations reinforce sexism and masculine bias, those with teaching orientations combat and reject it. The purpose of this study was to examine four sport education (SE) seasons taught by two experienced in-service teachers for the presence or absence of sexism and…

  12. A study on the effectiveness of self-assessment and peer assessment in the oral production of secondary EFL learners and CLIL learners

    OpenAIRE

    León Herrera, Yasmina

    2014-01-01

    This study compares the effects of peer assessment (PA) and self-assessment (SA) in the oral production of secondary English as a Foreign Language (EFL) students, half of them studying Maths in English in a Content and Language Integrated Learning (CLIL) model. The study examines the oral productions after three weeks of treatment comparing first, second and third recorded performances. In order to investigate the effectiveness of these two types of assessments, the treatment w...

  13. A probabilistic safety assessment PEER review: Case study on the use of probabilistic safety assessment for safety decisions

    International Nuclear Information System (INIS)

    The purpose of this case study is to illustrate, using an actual example, the organizing and carrying out of an independent peer review of a draft full-scope (level 3) probabilistic safety assessment. The specific findings of the peer review are of less importance than the approach taken, the interaction between sponsor and study team, and the technical and administrative issues that can arise during a peer review. This case study will examine the following issues: how the scope of the peer review was established, based on how it was to be used by the review sponsoring body; how the level of effort was determined, and what this determination meant for the technical quality of the review; how the team of peer reviewers was selected; how the review itself was carried out; what findings were made; what was done with these findings by both the review sponsoring body and the PSA analysis team. 9 refs, 2 figs, 1 tab

  14. Profiling postgraduate workplace-based assessment implementation in Ireland: a retrospective cohort study

    OpenAIRE

    Barrett, Aileen; Galvin, Rose; Steinert, Yvonne; Scherpbier, Albert; O’Shaughnessy, Ann; Walsh, Gillian; Horgan, Mary

    2016-01-01

    In 2010, workplace-based assessment (WBA) was formally integrated as a method of formative trainee assessment into 29 basic and higher specialist medical training (BST/HST) programmes in six postgraduate training bodies in Ireland. The aim of this study is to explore how WBA is being implemented and to examine if WBA is being used formatively as originally intended. A retrospective cohort study was conducted and approved by the institution’s Research Ethics Committee. A profile of WBA require...

  15. An assessment of five different theoretical frameworks to study the uptake of innovations

    OpenAIRE

    Botha, Neels; Atkins, Kris

    2005-01-01

    There are several theoretical frameworks one can draw upon to study the adoption process. Extension Theory, Bounded Rationality, Diffusion Theory, the Theory of Reasoned Action and Consumer Behaviour Theory were of particular interest to us. In assessing the frameworks we looked for contradictions, and how and whether these frameworks could be used to study the adoption process. The assessment was done by using our own conceptual framework of the adoption process and we discuss the results in...

  16. Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies

    OpenAIRE

    Bossuyt Patrick NM; Reitsma Johannes B; Rutjes Anne WS; Weswood Marie E; Whiting Penny F; Kleijnen Jos

    2006-01-01

    Abstract Background A quality assessment tool for diagnostic accuracy studies, named QUADAS, has recently been developed. Although QUADAS has been used in several systematic reviews, it has not been formally validated. The objective was to evaluate the validity and usefulness of QUADAS. Methods Three reviewers independently rated the quality of 30 studies using QUADAS. We assessed the proportion of agreements between each reviewer and the final consensus rating. This was done for all QUADAS i...

  17. Need Assessment for Sex Education amongst the University Students –A Pilot Study

    OpenAIRE

    Jaideep Kumar

    2012-01-01

    Background: The morbidity associated with sexual ignorance, poor decision making and inadequate sexuality education is rising in India day by day. The possibility of sex related public health problems like sexual abuse, teenage pregnancies, abortions, unmarried motherhood, STD/HIV infections etc. are always remains high in university students. In this background to assess the student’s knowledge & perceived need for sex education this study was conducted. Objective Of Study: To assess the nee...

  18. Reproducibility in echocardiographic assessment of diastolic function in a population based study (the STANISLAS Cohort study.

    Directory of Open Access Journals (Sweden)

    Zied Frikha

    Full Text Available There is limited evidence regarding intra-observer and inter-observer variations in echocardiographic measurements of diastolic function. This study aimed to assess this reproducibly within a population-based cohort study.Sixty subjects in sinus rhythm were randomly selected among 4th visit participants of the STANISLAS Cohort (Lorraine region, France. This 4th examination systematically included M-mode, 2-dimensional, DTI and pulsed-wave Doppler echocardiograms. Reproducibility of variables was studied by intra-class correlation coefficients (ICC and Bland Altman plots.Our population was on average middle-aged (50 ± 14 y, overweight (BMI = 26 ± 6 kg/m2 and non-smoking (87% with a quarter of the participants having self-declared hypertension or treated with anti-hypertensive medication(s. Intra-observer ICC were > 0.90 for all analyzed parameters except for left ventricular ejection fraction (LVEF which was 0.89 (0.81-0.93. The mean relative intra-observer differences were small and limits of agreement of relative differences were narrow for all considered parameters ( 0.90 for all analyzed parameters except for LVEF (ICC = 0.87 and both mitral and pulmonary A wave duration (0.83 and 0.73 respectively. The mean relative inter-observer differences were <5% for all parameters except for pulmonary A wave duration (mean difference = 6.5%. Limits of agreement of relative differences were narrow (<15%, except for mitral A wave duration and velocity (both <20% as well as left ventricular mass and pulmonary A wave duration (both <30%. Intra-observer agreements with regard to the presence and severity of diastolic dysfunction were excellent (Kappa = 0.93 (0.83-1.00 and 0.88 (0.75-0.99, respectively.In this validation study within the STANISLAS cohort, diastolic function echocardiographic parameters were found to be highly reproducible. Diastolic dysfunction consequently appears as a highly effective clinical and research tool.

  19. Does high dose rate irradiation of obstructive intrabronchial malignancy justify the high cost? A study of 83 patients

    International Nuclear Information System (INIS)

    Purpose: Over a 6 year period, 1989 through 1994, 83 patients (pts) (76 pts with primary lung carcinoma (ca) and 7 pts with a solitary metastic lesion to the lung) and with bronchoscopically identified obstructive tumor, causing symptoms (sx's) of cough, hemoptysis and/or shortness of breath (SOB) were treated with high dose rate (HDR) Ir-192 intrabronchial irradiation (XRT), and are the basis of this study. The purpose of this retrospective study is to determine the survival and relief of sx's, compare our results to those in the classic radiation oncology lung ca literature, and determine if the improvement is sufficient to justify the high cost of adding HDR XRT to standard external beam XRT. Methods and Materials: 44 pts presented with de novo disease and initially received a course of external beam XRT (5000 - 6000 cGy, standard fractionation) followed by 3 HDR tx's of 800 cGy per treatment (tx) calculated at one cm depth, separated by one week intervals, for a total HDR dose of 2400 cGy. 39 pts presented with locally recurrent disease following prior tx with external beam XRT, and they received 3 HDR tx's, 1000 cGy per tx, one cm from the center of the catheter, separated by one week intervals, for a total dose to the tumor of 3000 cGy. All patients presented with one or more obstructive sx's. Relief of these sx's were determined at last follow-up (FU) or until death. All patients have been followed for a minimum of 6 months (mos). Results: Our results show overall median survivals of 13 mos since initial diagnosis and 6 mos since treatment. In light of these results, we attempted to determine a subgroup of patients who might have a statistically significant increase in survival. The subgroups we analyzed were 1) pts with recurrent disease, 2) those treated in later years of the study, surmising we were more selective as our experience increased, 3) squamous histology with its natural history to remain localized, and 4) younger patients, age below 50. Our

  20. Retrospective exposure assessment and quality control in an international multi-centre case-control study

    DEFF Research Database (Denmark)

    Tinnerberg, H; Heikkilä, P; Huici-Montagud, A;

    2003-01-01

    to the original CA studies at the time of CA testing, but not for the whole work life. An independent occupational hygienist coordinated harmonization of the assessment criteria and the quality control procedure. The reliability of the exposure assessments was calculated as deviation from the majority......The paper presents the exposure assessment method and quality control procedure used in an international, multi-centre case-control study within a joint Nordic and Italian cohort. This study was conducted to evaluate whether occupational exposure to carcinogens influenced the predictivity of high...... was higher among the original assessors (the assessor from the same country as the subject) than the average prevalence assessed by the other four in the quality control round. The original assessors classified more job situations as exposed than the others. Several reasons for this are plausible: real...

  1. The clinical impact of perfusion scintigraphy with dipyridamole

    International Nuclear Information System (INIS)

    In order to assess their clinical impact, the authors analyzed perfusion scintigrams (PS) with dipyridamole (D) and the resultant clinical management in 41 consecutive patients (PTS). Population mean age was 67, with 22 males and represented 14% of those having PS. Fifteen PTS had rest chest pain of unknown cause and 26 PTS had pain typical or suggestive of angina but couldn't undergo dynamic stress due to claudication, arthritis, amputation, stroke, recent surgery or other disability. Four PTS were studies for surgical clearance, 3 following angiography to assess coronary pathophysiology and 9 had prior negative or equivocal stress PS at suboptimal levels. Among 18 PTS with reversible scintigraphic abnormalities, 10 underwent subsequent catheterization, with successful CABG in 7, PTCA in 1, aggressive medical treatment of ischemia in 11, and 2 had noncoronary surgery delayed. One PT with associated extensive fixed abnormalities underwent CABG and died late in heart failure. Among 23 PTS without significant scintigraphic reversibility, 8 with normal studies were discharged, 3 went on to uncomplicated noncardiac surgery and 11 PTS, 9 with dilated cardiomyopathy, were managed without therapeutic change. D infusion was uncomplicated and related findings on PS correlated well with coronary angiography, where available in 19 of 20 PTS. PS with D: 1) is safe; 2) correlates closely with coronary anatomy; and 3) adds unique, important pathophysiologic information to clinical evaluation and impacts strongly on the management of a large number of PTS with known or suspected coronary disease

  2. An Assessment of the Study Habits and Skills of Students in Postsecondary Science Courses.

    Science.gov (United States)

    Kuhn, David J.

    1988-01-01

    Discusses a study conducted at Wilson County Technical College, North Carolina, to assess the study habits and skills of 74 students enrolled in basic science courses in 1987. Student responses to the Study Behavior Inventory-Form D suggest that students had difficulty with time management and keeping up-to-date with assignments. (DMM)

  3. Constructivist assessment proposal a case study in a technical and industrial school environment

    Directory of Open Access Journals (Sweden)

    Carol Yohana Suescún Pinilla

    2012-11-01

    Full Text Available This article is part of the ongoing research “Constructivist AssessmentProposal” held at Institución Educativa Técnica Integral in Sogamoso. It isaimed at identifying why the assessment traditional approach is still beingapplied. Besides, it pretends to redefine new assessment practices in order toenhance students’ participation, speech and creativity. Likewise, it tends tomake teachers be aware of alternative assessment ways more relevant withthe education needs and demands. It is based on the case study researchapproach and developed in three stages: problematic description andcontextualization, analysis and comprehension of the assessment used bythe teacher in a technical and industrial setting and improvement alternativeproposals based on the problematic situation.

  4. Questioning western assessment of trauma among Tibetan torture survivors. A quantitative assessment study with comments from Buddhist Lamas

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Jespersen, Kristian;

    2009-01-01

    did not have an influence on the level of distress. After the assessment study, eight Tibetan lamas were interviewed about their views on our methods and results. They questioned the validity of our western rating scales and explained that our results might be influenced by the Tibetan culture, which...... Symptom Checklist 25 (HSCL-25). Even though significant correlations between the amount of the measures of organized violence and neuropsychological and psychological distress were found in our data, the division of the material into different subgroups according to e.g. religious and non-religious groups...... among other things can be characterized as having a view and articulation of suffering much more complex than the units of our study's rating scales....

  5. Phd study of reliability and validity: One step closer to a standardized music therapy assessment model

    DEFF Research Database (Denmark)

    Jacobsen, Stine Lindahl

    The paper will present a phd study concerning reliability and validity of music therapy assessment model “Assessment of Parenting Competences” (APC) in the area of families with emotionally neglected children. This study had a multiple strategy design with a philosophical base of critical realism...... and pragmatism. The fixed design for this study was a between and within groups design in testing the APCs reliability and validity. The two different groups were parents with neglected children and parents with non-neglected children. The flexible design had a multiple case study strategy specifically...... of the theoretical understanding of the clientgroup. Furthermore, a short describtion of the specific assessment protocol and analysis procedures of APC will be a part of the presentation. The phd study sought to explore how to develop measures of parenting competences in looking at autonomy relationship...

  6. Evaluation of a new clinical performance assessment tool : A reliability study

    Directory of Open Access Journals (Sweden)

    C. Joseph

    2012-12-01

    Full Text Available Clinical practice is an essential requirement of any graduatephysiotherapy programme. For this purpose, valid and reliable assessment toolsare paramount for the measurement of key competencies in the real-worldsetting. This study aims to determine the internal consistency and inter-raterreliability of a newly developed and validated clinical performance assessmentform. A cross-sectional quantitative research design was used, which includedpaired evaluations of 32 (17 treatment and 15 assessment student examinationsperformed by two independent clinical educators. Chronbachs alpha was computedto assess internal consistency and intraclass correlation coefficient (ICC’s withconfidence intervals of 95% were computed to determine the percentage agreement between paired examiners. Thedegree of internal consistency was substantial for all key performance areas of both examinations, except for timeand organisational management (0.21 and professionalism (0.42 in the treatment and evaluation examinationsrespectively. The overall internal consistency was 0.89 and 0.73 for both treatment and assessment examinations,indicating substantial agreement. With regard to agreement between raters, the ICC’s for the overall marks were0.90 and 0.97 for both treatment and assessment examinations. Clinical educators demonstrated a high level ofreliability in the assessment of students’ competence using the newly developed clinical performance assessment form.These findings greatly underscore the reliability of results obtained through observation of student examinations, andadd another tool to the basket of ensuring quality assurance in physiotherapy clinical practice assessment.

  7. A study on assessment methodology of surveillance test interval and allowed outage time

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Chang Hyun; You, Young Woo; Cho, Jae Seon; Huh, Chang Wook; Kim, Do Hyoung; Kim, Ju Youl; Kim, Yoon Ik; Yang, Hui Chang; Park, Kang Min [Seoul National Univ., Seoul (Korea, Republic of)

    1998-03-15

    The objectives of this study is the development of methodology by which assesses the optimization of Surveillance Test Internal(STI) and Allowed Outage Time(AOT) using PSA method that can supplement the current deterministic methods and the improvement of Korean nuclear power plant safety. In this study, the survey about the assessment methodologies, modelings and results performed by domestic and international researches are performed as the basic step before developing the assessment methodology of this study. The assessment methodology that supplement the revealed problems in many other studies is presented and the application of new methodology into the example system assures the feasibility of this method. The sensitivity analyses about the failure factors of the components are performed in the bases of the and AOT is quantified. And the reliability assessment methodology about the diesel generator is reviewed and applied to the PSA code. The qualitative assessment for the STI/AOR of RPS/ESFAS assured safety the most important system in the nuclear power plant are performed.

  8. The Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals (BEES-C) Instrument for Assessing Study Quality

    Science.gov (United States)

    Environmental epidemiology studies can be an effective means to assess impacts on human health from exposure to environmental stressors. Exposure scenarios are often extremely complex and proper assessment is critical for interpreting epidemiological study results. Biomarkers are...

  9. Study of personality’s temperament and self-assessment of higher educational establishments’ students

    Directory of Open Access Journals (Sweden)

    Liashenko V.N.

    2016-04-01

    Full Text Available Purpose: analysis of temperament and self-assessment characteristics in higher educational establishment students. Material: in the research 1st and 2nd year students (n=30 participated. Questioning was used, with the help of which personality’s self assessment and temperament characteristics were estimated. Results: the study of students’ temperament structure showed low demand in mastering of objective world and strive for mental and physical labor. High indicator of social activity and interpersonal skills was registered. The following indicators of self-assessment were received: 15% of students had too low self-assessment, 50% of students have adequate self-assessment and 10% have excessively high self-assessment. Conclusions: quickness of psychic processes (tem and rhythm, impressiveness and emotional sensitivity are important features of temperament. Students demonstrated feeling of anxiety and worry in respect to their studying at university. Besides the have sensitivity to failures to non coincidence of the desired and the results. студентов. With it students have adequate self assessment.

  10. A study on the reliability and risk assessment of nuclear power plants

    International Nuclear Information System (INIS)

    The final objective of the present study is to establish the foundations of both performing statistical analyses of various failures and potential accidents in nuclear power plants and assessing probabilistic safety. In order to achive the objective, we have chosen the review of the state of the arts in the related methodologies and the establishment of reliability analysis method as study areas in this year. The works performed are summalized here. First, the brief reviews of the present status on the Probabilistic Risk Assessment and the development of quantiative safety goal in the Unite States were completed. It has been identified that the Probabilistic Risk Assessment techniques will take important role in nuclear safety assessment as a supporting tool in coming years. In order to establish reliability analysis methodology, a computer code for updating plant specific reliability data has been developed as a part of this project. A reliability analysis system has been estabished and used to analyize the axiliary feedwater system. (Author)

  11. THE SELF-ASSESSMENT PROCESS AND IMPACTS ON PERFORMANCE: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Juan José Tarí

    2012-12-01

    Full Text Available The purpose of this paper is to analyze the effectiveness of the European Foundation for Quality Management model self-assessment process and its effects on performance in a private manufacturing firm. A case study is used, considering the analysis of primary and secondary data. This paper explains the self-assessment process using a workshop approach, and identifies benefits, difficulties and success factors. It also shows that self-assessment has partly improved performance and the attitudes and behaviour of management and employees, reinforcing the firm’s competitiveness. The contribution of this paper is to provide lessons for managers of other organisations to learn from.

  12. Study on wave energy resource assessing method based on altimeter data—A case study in Northwest Pacific

    Institute of Scientific and Technical Information of China (English)

    WAN Yong; ZHANG Jie; MENG Junmin; WANG Jing; DAI Yongshou

    2016-01-01

    Wave energy resource is a very important ocean renewable energy. A reliable assessment of wave energy resources must be performed before they can be exploited. Compared with wave model, altimeter can provide more accuratein situ observations for ocean wave which can be as a novel method for wave energy assessment. The advantage of altimeter data is to provide accurate significant wave height observations for wave. In order to develop characteristic and advantage of altimeter data and apply altimeter data to wave energy assessment, in this study, we established an assessing method for wave energy in local sea area which is dedicated to altimeter data. This method includes three parts including data selection and processing, establishment of evaluation indexes system and criterion of regional division. Then a case study of Northwest Pacific was performed to discuss specific application for this method. The results show that assessing method in this paper can assess reserves and temporal and spatial distribution effectively and provide scientific references for the siting of wave power plants and the design of wave energy convertors.

  13. Identifying Distinct Quitting Trajectories after an Unassisted Smoking Cessation Attempt: An Ecological Momentary Assessment Study

    OpenAIRE

    Bachmann, Monica S.; Znoj, Hansjörg; Brodbeck, Jeannette

    2012-01-01

    Objectives: This study aimed at identifying distinct quitting trajectories over 29 days after an unassisted smoking ces- sation attempt by ecological momentary assessment (EMA). In order to validate these trajectories we tested if they predict smoking frequency up to six months later. Methods: EMA via mobile phones was used to collect real time data on smoking (yes/no) after an unassisted quit attempt over 29 days. Smoking frequency one, three and six months after the quit attempt was assesse...

  14. Quantitative Assessment of Airborne Exposures Generated during Common Cleaning Tasks: A Pilot Study

    OpenAIRE

    Perry Melissa J; Quinn Margaret M; Bello Anila; Milton Donald K

    2010-01-01

    Abstract Background A growing body of epidemiologic evidence suggests an association between exposure to cleaning products with asthma and other respiratory disorders. Thus far, these studies have conducted only limited quantitative exposure assessments. Exposures from cleaning products are difficult to measure because they are complex mixtures of chemicals with a range of physicochemical properties, thus requiring multiple measurement techniques. We conducted a pilot exposure assessment stud...

  15. Is objective and accurate cognitive assessment across the menstrual cycle possible? A feasibility study

    OpenAIRE

    Farrar, Diane; Neill, Jo; Scally, Andy; Tuffnell, Derek; Marshall, Kay

    2015-01-01

    Objectives: Variation in plasma hormone levels influences the neurobiology of brain regions involved in cognition and emotion processing. Fluctuations in hormone levels across the menstrual cycle could therefore alter cognitive performance and wellbeing; reports have provided conflicting results, however. The aim of this study was to assess whether objective assessment of cognitive performance and self-reported wellbeing during the follicular and luteal phases of the menstrual cycle is feasib...

  16. A socio-constructivist perspective on self-assessment: a study case

    Directory of Open Access Journals (Sweden)

    Paola Nicolini

    2009-10-01

    Full Text Available In this paper, our goal is to deal with self-assessment according to a socio-constructivist approach. We offer some data about different versions of the same Workshop, considered as a case study. Between the possibility to adopt a completely goal-driven or a fully goal-free self assessment, we suggest the adoption of a blended modality, in order to involve students in the learning process and make them aware about the learning outcomes.

  17. LIFE CYCLE ASSESSMENT FOR OIL PALM BASED PLYWOOD: A GATE-TO-GATE CASE STUDY

    OpenAIRE

    M. Shamim Ahmad; Vijaya Subramaniam; Halimah Mohammad; Anis Mokhtar; Ismail, B. S.

    2014-01-01

    Life Cycle Assessment (LCA) is an important tool for identifying potential environmental impacts associated with the production of palm based plywood. This study is to make available the life cycle inventory for gate-to-gate data so that the environmental impact posed by oil palm based plywood production can be assessed. Conducting an LCA on the palm based plywood that are derived from the wastes of the oil palm industry is a first step towards performing green environmental product. Therefor...

  18. PERFORMANCE ASSESSMENT OF PRODUCT DEVELOPMENT PROCESS IN A BUS COMPANY: A CASE STUDY

    OpenAIRE

    Tiago Ribeiro de Araújo; Fernanda Cristina Pierre

    2014-01-01

    This article aims to examine the application of a method for assessing the performance of the product development process (PDP) through the assessment of managerial skills in a bus body industry. A case study was carried out and a PDP method was applied through a questionnaire addressing the PDP management skills according to Dechamps and Nayak (1997) model and validated by Silva (2001) in a bus body company which showed all the features available in the literature on industria...

  19. The importance of landscape attributes in biodiversity assessment. The Évora case study.

    OpenAIRE

    Quinta-Nova, L.C.; Batista, T.

    2001-01-01

    The study of wildlife communities to assess the landscape value is crucial in Landscape Ecology in order to develop bidiversity management strategies in rural landscapes and to assist land managers with their decision making processes. This poster reports the results achieved assessing biodiversity using landscape structural indicators. The main objective was to identify the landscape measures having a greater influence on the presence of avian communities in agrosystems located around Évora ...

  20. A Case Study in Support of Multiple Post Mortem Assessments (Invited Paper)

    OpenAIRE

    Jill Pable; Kenan Fishburne

    2015-01-01

    Creative projects in various fields are often subjected to afterthe- fact 'post-mortem' assessments to better understand their successes and failures. Names for these include project retrospectives or post occupancy evaluations (POEs) depending on their field of origin. This case study from the architecture field will show the utility of engaging in multiple rounds of post-mortem activities in order to assess the solution from multiple stakeholder perspectives and in doing so, more fully reco...

  1. Web-based Peer Assessment: A Case Study with Civil Engineering Students

    OpenAIRE

    Gonçalo Cruz; Caroline Dominguez; Ana Maia; Daniela Pedrosa; Gordon Grams

    2013-01-01

    Peer-assessed online collaborative writing is of growing importance for higher education. Based on the quantitative and qualitative analysis of collected data, this work presents the results of a case study in a graduate civil engineering course at the University of Trás-os-Montes e Alto Douro, Vila Real, Portugal. After an overall presentation of the learning activity, it examines students’ attitudes towards web-based peer assessment and identifies which factors are rela...

  2. Assessment of Osstell ISQ's reliability for implant stability measurement: a cross-sectional clinical study

    OpenAIRE

    Herrero Climent, Mariano; Santos García, Rocío; Jaramillo Santos, Reyes; Romero Ruiz, Manuel María; Fernández Palacín, Ana; Lázaro Calvo, Pedro; Bullón, Pedro; Ríos Santos, José Vicente

    2013-01-01

    Resonance frequency analysis (RFA) allows assess implant stability by measuring implant oscillation frequency on the bone. RFA is an objective and non-invasive method for implant stability measurement, although scarce evidence has been provided so far on its reliability. Objectives: Assess the Osstell ISQ system’s reliability (i.e., its measurement reproducibility and repeatability) by means of the intraclass correlation coefficient (ICC) as statistical method. Study Desing: Implants stabilit...

  3. Assessment of physical activity in epidemiological studies: Are questionnaires obsolete in the era of accelerometry?

    Directory of Open Access Journals (Sweden)

    Brühmann, Boris A.

    2014-07-01

    Full Text Available [english] Background: The rapid development in technology promotes the increasing use of electronic activity monitors to assess physical activity in large-scale epidemiological studies. Our aim was to explore and discuss both subjective and objective methods assessing physical activity.Methods: Based on a thorough literature search, major strengths and limitations of questionnaires and electronic activity monitors in assessing physical activity are elaborated and discussed, taking into consideration physical activity in all its complexity. Important research questions and the aim and scope of physical activity assessment for next-generation research are defined.Results: Questionnaires can provide details and background information of physical activity, including type of activity, and can identify the activity behaviour patterns that underlie measurable endpoints such as energy expenditure, cardiorespiratory fitness, muscular strength, or certain biomarkers. They can differentiate well between settings and enable retrospective assessment. Electronic activity monitors, on the other hand, are rapidly becoming better at assessing energy expenditure and are good at quantifying the amount and intensity of physical activity and sedentary behaviour. Both methods, however, also have their weaknesses. While questionnaires may not be accurate, due to recall bias or incomplete assessment of all activity domains, electronic activity monitors are not able to provide information about setting, exact type and mode of activity, and cannot recognize and reliably assess resistance exercise or activities with or without carrying weights.Conclusions: Since physical activity is multidimensional and complex, no single method is suitable to capture all aspects and domains. Both methods have their strengths and limitations and do not compete with each other, but should be seen as complementary tools that assess distinct aspects of physical activity. Studies should

  4. 75 FR 1793 - Study Team for the Los Alamos Historical Document Retrieval and Assessment (LAHDRA) Project

    Science.gov (United States)

    2010-01-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Study Team for the Los Alamos Historical...: Public Meeting of the Study Team for the Los Alamos Historical Document Retrieval and Assessment...

  5. Assessment of mastication in healthy children and children with cerebral palsy: a validity and consistency study

    NARCIS (Netherlands)

    Remijn, L.; Speyer, R.; Groen, B.E.; Holtus, P.C.; Limbeek, J. van; Nijhuis-Van der Sanden, M.W.G.

    2013-01-01

    The aim of this study was to develop the Mastication Observation and Evaluation instrument for observing and assessing the chewing ability of children eating solid and lumpy foods. This study describes the process of item definition and item selection and reports the content validity, reproducibilit

  6. Understanding Perspectives of English Language Learning and Assessment Practices: A Mixed-Method Embedded Study

    Science.gov (United States)

    Bailey, Angela Christine

    2013-01-01

    This study contributed to the continuing dialogue of quality language programs and student outcomes for classroom language learning and assessments within the standardized testing era to language learning programs within Colombia. The particular purpose of this one-phase, embedded, mixed-method study examined students' and teachers' beliefs about…

  7. Assessing Honor Code Effectiveness: Results of a Multipronged Approach from a Five Year Study

    Science.gov (United States)

    Sledge, Sally; Pringle, Pam

    2010-01-01

    This paper describes an ongoing study at a small public university to assess student, faculty and alumni perceptions of academic integrity and business ethics. The phases of the research are detailed for application or replication by other institutions of higher education. The study involves anonymous surveys and academic integrity-based…

  8. Do Plot Scale Studies Yield Useful Data When Assessing Field Scale Practices?

    Science.gov (United States)

    Plot scale data has been used to develop models used to assess field and watershed scale nutrient losses. The objective of this study was to determine if phosphorus (P) loss results from plot scale rainfall simulation studies are “directionally correct” when compared to field scale P losses. Two fie...

  9. Systematic review of foodborne burden of disease studies: Quality assessment of data and methodology

    NARCIS (Netherlands)

    J.A. Haagsma (Juanita); S. Polinder (Suzanne); C. Stein (Claudia); A.H. Havelaar (Arie)

    2013-01-01

    textabstractBurden of disease (BoD) studies aim to identify the public health impact of different health problems and risk factors. To assess BoD, detailed knowledge is needed on epidemiology, disability and mortality in the population under study. This is particularly challenging for foodborne dise

  10. Field procedures in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

    OpenAIRE

    Heeringa, Steven G.; Gebler, Nancy; Colpe, Lisa J.; Carol S Fullerton; Hwang, Irving; Ronald C. Kessler; Naifeh, James A.; Nock, Matthew K.; Sampson, Nancy A; Schoenbaum, Michael; Zaslavsky, Alan M.; Stein, Murray B.; Ursano, Robert J.

    2013-01-01

    The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multi-component epidemiological and neurobiological study of unprecedented size and complexity designed to generate actionable evidence-based recommendations to reduce U.S. Army suicides and increase basic knowledge about determinants of suicidality by carrying out coordinated component studies. A number of major logistical challenges were faced in implementing these studies. The current report presents an overv...

  11. Validation of the automatic image analyser to assess retinal vessel calibre (ALTAIR): a prospective study protocol

    OpenAIRE

    Garcia-Ortiz, Luis; Gómez-Marcos, Manuel A.; Recio-Rodríguez, Jose I; Maderuelo-Fernández, Jose A; Chamoso-Santos, Pablo; Rodríguez-González, Sara; de Paz-Santana, Juan F; Merchan-Cifuentes, Miguel A; Corchado-Rodríguez, Juan M

    2014-01-01

    Introduction The fundus examination is a non-invasive evaluation of the microcirculation of the retina. The aim of the present study is to develop and validate (reliability and validity) the ALTAIR software platform (Automatic image analyser to assess retinal vessel calibre) in order to analyse its utility in different clinical environments. Methods and analysis A cross-sectional study in the first phase and a prospective observational study in the second with 4 years of follow-up. The study ...

  12. A COMPARATIVE STUDY TO ASSESS FETAL MALNUTRITION BY CLINICAL ASSESSMENT OF NUTRITIONAL STATUS SCORE (CAN SCORE AND ANTHROPOMETRIC INDICES

    Directory of Open Access Journals (Sweden)

    Thammanna

    2015-09-01

    Full Text Available CONTEXT: Fetal malnutrition is a major problem in developing countries like India. It is associated with increased mortality and long term sequel . There are various methods to determine nutritional status of newborns like weight for gestational age, Ponderal index, Body mass index, mid arm circumference/ head circumference ratio etc., but each have their own limitations. The terms fetal malnutrition and small for gestational age are not synonymous and one may occur without the other. Clinical assessment of nutrition al status score (CAN Score developed by Metcoff is a reliable test for identification of fetal malnutrition. This study was under taken to identify incidence of fetal malnutrition by CAN Score and to compare it with other anthropometric indices. METHODS: It was a prospective study conducted in a tertiary care hospital. 256 neonates were assessed using CAN Score and anthropometry was recorded. Neonates were classified as per weight for age. Ponderal index, body mass index, mid arm circumference/ head circum ference ratio, body mass index were calculated and compared with CAN Score for accuracy in identifying fetal malnutrition. RESULTS: Incidence of fetal malnutrition as per CAN Score was 26.17%, 6.4% of Appropriate for gestational age babies were malnourishe d. Weight for age parameter classified 28.52% of babies as malnourished; Ponderal index classified 23.44% as malnourished, body mass index and mid arm circumference/ head circumference ratio classified 39.45% and 34.38% neonates as malnourished respectivel y. Weight for age and body mass index had sensitivity of 83.58% and 80.6% respectively in identifying fetal malnutrition. CONCLUSION: CAN score is a simple clinical method for identification of fetal malnutrition without use of any sophisticated equipments and it can even detect malnourished babies who are missed by other anthropometric methods

  13. LEARNING ASSESSMENT: A STUDY BASED ON THE PERCEPTIONS OF UNDERGRADUATE MANAGEMENT STUDENTS

    Directory of Open Access Journals (Sweden)

    Marianny Jessica de Brito Silva

    2015-06-01

    Full Text Available This paper aimed to identify the perception of undergraduate Management course students from the Federal University of Pernambuco (UFPE, Agreste Campus, about their professors’ assessment methods. A quantitative approach was employed through a questionnaire conducted on a research sample of 155 students. The data collected and analyzed revealed that the students in question pointed out didactic and bureaucratic functions as the reasons for undertaking assessments and recognized their importance only for students, as an indication of their performance. Most students stated that their feelings about the assessment processes vary according to their time of study and empathy for the discipline, and that the teaching-assessment ratio is generally positive. Assessment feedback was common practice for the sample, but there was a lack of diversity of assessment tools and those used clash with the ones they desired. In conclusion, according to the students’ perception, it is possible to develop multiple thoughts about the assessment process, driving improvements in educational practices and the formation and training of university professors.

  14. Assessing progression of clinical reasoning through virtual patients: An exploratory study.

    Science.gov (United States)

    Forsberg, Elenita; Ziegert, Kristina; Hult, Håkan; Fors, Uno

    2016-01-01

    To avoid test-driven learning, there have been discussions regarding the use of more formative assessments in health care education to promote students' deep learning. Feedback is important in formative assessment, but many students ignore it; therefore, interventions should be introduced which stimulate them to reflect on the new knowledge. The aim for this study was to explore if Virtual Patient (VP)-based formative assessments, in connection with self-evaluations, had an impact on postgraduate pediatric nursing students' development of clinical reasoning abilities. Students' self-evaluations served as the basis for measuring progress. Data was analysed using deductive content analysis. The findings showed a clear progression of the clinical reasoning ability of the students. After the first assessment, the students described feelings of uncertainty and that their knowledge gaps were exposed. At the mid-course assessment the awareness of improved clinical reasoning was obvious and the students were more certain of knowing how to solve the VP cases. In the final assessment, self-efficacy was expressed. VP-based assessments, in connection with self-evaluations, early in the education resulted in a gain of students' own identification of the concept of clinical reasoning, awareness of what to focus on during clinical practice and visualised expected clinical competence. PMID:26482401

  15. Assessing progression of clinical reasoning through virtual patients: An exploratory study.

    Science.gov (United States)

    Forsberg, Elenita; Ziegert, Kristina; Hult, Håkan; Fors, Uno

    2016-01-01

    To avoid test-driven learning, there have been discussions regarding the use of more formative assessments in health care education to promote students' deep learning. Feedback is important in formative assessment, but many students ignore it; therefore, interventions should be introduced which stimulate them to reflect on the new knowledge. The aim for this study was to explore if Virtual Patient (VP)-based formative assessments, in connection with self-evaluations, had an impact on postgraduate pediatric nursing students' development of clinical reasoning abilities. Students' self-evaluations served as the basis for measuring progress. Data was analysed using deductive content analysis. The findings showed a clear progression of the clinical reasoning ability of the students. After the first assessment, the students described feelings of uncertainty and that their knowledge gaps were exposed. At the mid-course assessment the awareness of improved clinical reasoning was obvious and the students were more certain of knowing how to solve the VP cases. In the final assessment, self-efficacy was expressed. VP-based assessments, in connection with self-evaluations, early in the education resulted in a gain of students' own identification of the concept of clinical reasoning, awareness of what to focus on during clinical practice and visualised expected clinical competence.

  16. Vulnerability and Risk Assessment of Extreme Weather Events- A Case Study from Bangladesh

    Science.gov (United States)

    Fakhruddin, S.; Mukand, M. S.; Kawasaki, A.; Webster, P. J.

    2013-12-01

    Assessment of hazard, vulnerability and risk of extreme weather are essential in order to inform and implement appropriate adaptation/prevention/mitigation strategies. Due to complex nature and uncertainties in future climate change predictions, it is not feasible to detail assessment of vulnerability at detailed scales for potential hazard and risk. Though different approaches and methods exist for running hazard, vulnerability and risk assessment, but still difficult to address all physical science, engineering, and social science research. In this study, we try to discuss on the human vulnerability and risk assessment approaches, tools and techniques of natural hazard due to extreme weather events (i.e. floods, cyclone). We analyzed different approaches and methods of vulnerability and risk assessment for flood hazard based on medium (1-10 days) and seasonal (1-3 months) ensembles probabilistic forecasts. The multiple weather ensembles (EPS) forecasts of European Center for Medium Range Forecasts (ECMWF) and downscaled Community Climate System Model Version 3 (CCSM3) forecasts data were used to set up hydrological model. Due to high uncertainty in forecasts information, results summarized that data and inherent low resolutions of the information are major constrains for details comprehensive assessment. Risk and vulnerability rises to be based on multi-scale and cross-scale analyses, considering resilience dimensions and provide innovative tools for understanding, assessing and communicating probabilistic information to the users for decision making. The sectoral responses were developed with possible impacts scenarios based on uncertainty ranges to choose the most robust solution.

  17. Worth it? Findings from a study of how academics assess students’ Web 2.0 activities

    Directory of Open Access Journals (Sweden)

    Kathleen Gray

    2012-02-01

    Full Text Available Educational commentators have offered many pedagogical rationales for using Web 2.0 to support learning in higher education, and academics are being encouraged to find ways for their students to use social web technologies. Questions arise as to the value of these activities compared to more conventional assignments, and whether implementing such changes to student assessment is worth the effort. We conducted a survey of academics’ assessment of students’ Web 2.0 activities in Australian universities and found that this form of assessment is being conducted by a small number of academics, in a range of fields of study, but mainly in Humanities and Social Sciences, with varying kinds of intended and actual learning outcomes. Blogging and wiki-writing predominate, low and medium-stakes assessment are most common, and different methods of marking and feedback are in use. Qualitative feedback from the survey and follow-up interviews gave further insights into benefits and challenges of Web 2.0 assessment in relation to pedagogy, policy and practice. It appears that academics’ conservative approaches to conducting assessment and their novice approaches to utilising social web technologies are factors which seriously limit realising the potential of Web 2.0 for medium or high-stakes assessment.

  18. Features of diagnosis and treatment of anemic syndrome in patients with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    N V Koryakova

    2009-01-01

    Full Text Available Features of diagnostics and course of anemic syndrome in rheumatoid arthritis patients Objective. To study features of anemic syndrome in rheumatoid arthritis (RA pts, to estimate influence of disease modifying anti – rheumatic drug therapy efficacy on the course of anemic syndrome. Material and methods. 62 pts with definite RA and level of hemoglobin less than 130g\\l for men and less than 120g\\l for women were examined. Research of hemoglobin, red cells count, mean corpuscular volume (MCV, mean concentration of hemoglobin (MCH, serum iron and ferritin was carried out. In a part of pts serum transferrin receptor and erythropoietin concentrations was defined. 30 pts were examined after 6 month of disease modifying therapy. Results. In 49(79 % of the pts the anemia was an easy degree of weight, MCH decreased in 33(53 % of the pts and 15(24 % pts had decreased values for MCV. Deficiency of iron in 16(26% of pts has been established at research of concentration a ferritin, sTfR and an index sTfR \\log ferritin. At the dynamic research after 6 month of disease modifying therapy the authentic gain levels of hemoglobin, red cells count and serum iron significantly increased in the pts with good and satisfactory effect of therapy. Сonclusion. Definition of MCH, MCV and ferrokinetic data for assessment of iron defi- ciency in the RА pts is necessary. sTfR and sTfR\\log ferritin may be study for pts with normal and increased ferritin levels. The major factor influencing on the course of anemia of chronic disease in the rheumatoid arthritis pts is the course rheumatoid arthritis, that efficacy disease modifying treatment to control.

  19. Establishing Normative Values for the Barnett Balance Assessment Tool: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Monica L. Cercone MSOTS

    2014-04-01

    Full Text Available The purpose of this study was to establish normative data for the Barnett Balance Assessment (BBA for individuals ages 18-70+ years. The BBA is a newly developed assessment tool that may address limitations present in other assessments currently used to detect balance deficits. The BBA was administered to 141 participants who had no history of medical issues that could impact balance. A review of the normative data collected indicated little variation in total assessment scores in the age categories of 18-29, 30-39, and 40-49, due to the presence of a ceiling effect. Variations existed in scores among participants in the remaining age categories (50-59, 60-69, and 70+. These findings may imply that the BBA has its greatest discriminative power in assessing individuals with impaired balance, and/or that the BBA is not sensitive enough to detect differences in individuals with mild balance impairments. The researchers suggest future studies be conducted with the BBA to establish norms with populations with known orthopedic or neurological conditions that may impair balance. Results of these studies could then be compared with the baseline data gathered in this study to determine the BBA’s usefulness in detecting balance impairments with clinical populations.

  20. Risk assessment of oil and gas well drilling activities in Iran - a case study: human factors.

    Science.gov (United States)

    Amir-Heidari, Payam; Farahani, Hadi; Ebrahemzadih, Mehrzad

    2015-01-01

    Oil and gas well drilling activities are associated with numerous hazards which have the potential to cause injury or harm for people, property and the environment. These hazards are also a threat for the reputation of drilling companies. To prevent accidents and undesired events in drilling operations it is essential to identify, evaluate, assess and control the attendant risks. In this work, a structured methodology is proposed for risk assessment of drilling activities. A case study is performed to identify, analyze and assess the risks arising from human factors in one of the on shore drilling sites in southern Iran. A total of 17 major hazards were identified and analyzed using the proposed methodology. The results showed that the residual risks of 100% of these hazards were in the acceptable or transitional zone, and their levels were expected to be lowered further by proper controls. This structured methodology may also be used in other drilling sites and companies for assessing the risks.

  1. Incorporating formative assessment and science content into elementary science methods---A case study

    Science.gov (United States)

    Brower, Derek John

    Just as elementary students enter the science classroom with prior knowledge and experiences, so do preservice elementary teachers who enter the science methods classroom. Elementary science methods instructors recognize the challenges associated with preparing teachers for the science classroom. Two of these challenges include overcoming limited science content understanding and a low science teaching efficacy. Based upon research in science misconceptions, conceptual change theory, formative assessment, and science teaching efficacy, this design experiment explored the use of formative assessment in an authentic learning environment to address some of these challenges. As a case study, the goal was to identify two specific topics in science which the preservice teachers did not understand and to model consistent use of formative assessment to guide instruction in those science topics for six weeks. The research questions for this study sought to explore the design of the class while also exploring students' understanding of the science content and their understanding of formative assessment. One specific question was whether the formative data could differentiate between deeply held student misconceptions in science and incomplete science understanding. In addition, data was collected to measure changes in science teaching efficacy as well as preservice teachers' desire to use formative assessment in their own future classrooms. Based upon student interviews and a final content quiz, the participants in this study did show improved science content understanding in the areas of plant food/energy and plate tectonics. The course design implemented a variety of formative assessment tools including formative assessment probes, student science notebooks, student concept maps, a non-graded quiz, and more. The STEBI-B survey identified improved science teaching efficacy among the participants. Student final essays indicated improved understanding of formative assessment

  2. Effect of continuous assessment on learning outcomes on two chemical engineering courses: case study

    Science.gov (United States)

    Tuunila, R.; Pulkkinen, M.

    2015-11-01

    In this paper, the effect of continuous assessment on the learning outcomes of two chemical engineering courses is studied over a several-year period. Average grades and passing percentages of courses after the final examination are reported and also student feedback on the courses is collected. The results indicate significantly better learning results after the adoption of continuous assessment in the courses. Also student feedback suggests higher quality in teaching after the adoption of more activating teaching methods which compel students to study effectively throughout the course.

  3. Final Report on Pilot Studies / Final Report on Classroom Research with STEM and TESL Assessment

    DEFF Research Database (Denmark)

    Biel, Carmen; Wake, Jo Dugstad; Hesse, Friedrich;

    This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables.......This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables....

  4. Recommendations by Cochrane Review Groups for assessment of the risk of bias in studies

    Directory of Open Access Journals (Sweden)

    Gøtzsche Peter C

    2008-04-01

    Full Text Available Abstract Background Assessing the risk of bias in individual studies in a systematic review can be done using individual components or by summarizing the study quality in an overall score. Methods We examined the instructions to authors of the 50 Cochrane Review Groups that focus on clinical interventions for recommendations on methodological quality assessment of studies. Results Forty-one of the review groups (82% recommended quality assessment using components and nine using a scale. All groups recommending components recommended to assess concealment of allocation, compared to only two of the groups recommending scales (P Conclusion We found that recommendations by some groups were not based on empirical evidence and many groups had no recommendations on how to use the quality assessment in reviews. We suggest that all Cochrane Review Groups refer to the Cochrane Handbook for Systematic Reviews of Interventions, which is evidence-based, in their instructions to authors and that their own guidelines are kept to a minimum and describe only how methodological topics that are specific to their fields should be handled.

  5. Contextual assessment of organisational culture - methodological development in two case studies

    International Nuclear Information System (INIS)

    Despite the acknowledged significance of organisational culture in the nuclear field, previous cultural studies have concentrated on purely safety related matters, or been only descriptive in nature. New kinds of methods, taking into account the overall objectives of the organisation, were needed to assess culture and develop its working practices appropriately. VTT developed the Contextual Assessment of Organisational Culture (CAOC) methodology during the FINNUS programme. The methodology utilises two concepts, organisational culture and core task. The core task can be defined as the core demands and content of work that the organisation has to accomplish in order to be effective. The core task concept is used in assessing the central dimensions of the organisation's culture. Organisational culture is defined as a solution the company has generated in order to fulfil the perceived demands of its core task. The CAOC-methodology was applied in two case studies, in the Radiation and Nuclear Safety Authority of Finland and in the maintenance unit of Loviisa NPP. The aim of the studies was not only to assess the given culture, but also to give the personnel new concepts and new tools for reflecting on their organisation, their jobs and on appropriate working practices. The CAOC-methodology contributes to the design and redesign of work in complex sociotechnical systems. It strives to enhance organisations' capability to assess their current working practices and the meanings attached to them and compare these to the actual demands of their basic mission and so change unadaptive practices. (orig.)

  6. Southeast Regional Assessment Study: an assessment of the opportunities of solar electric power generation in the Southeastern United States

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    The objective of this study was to identify and assess opportunities for demonstration and large scale deployment of solar electric facilities in the southeast region and to define the technical, economic, and institutional factors that can contribute to an accelerated use of solar energy for electric power generation. Graphs and tables are presented indicating the solar resource potential, siting opportunities, energy generation and use, and socioeconomic factors of the region by state. Solar electric technologies considered include both central station and dispersed solar electric generating facilities. Central stations studied include solar thermal electric, wind, photovoltaic, ocean thermal gradient, and biomass; dispersed facilities include solar thermal total energy systems, wind, and photovoltaic. The value of solar electric facilities is determined in terms of the value of conventional facilities and the use of conventional fuels which the solar facilities can replace. Suitable cost and risk sharing mechanisms to accelerate the commercialization of solar electric technologies in the Southeast are identified. The major regulatory and legal factors which could impact on the commercialization of solar facilities are reviewed. The most important factors which affect market penetration are reviewed, ways to accelerate the implementation of these technologies are identified, and market entry paths are identified. Conclusions and recommendations are presented. (WHK)

  7. A COMPARATIVE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF VALACYCLOVIR AND FAMCYCLOVIR IN THE MANAGEMENT OF HERPES ZOSTER IN A TERTIARY CARE HOSPITAL IN PUDUCHERRY

    Directory of Open Access Journals (Sweden)

    Indradev

    2014-05-01

    Full Text Available OBJECTIVE: The objective of this study was to compare the efficacy and safety of Valacyclovir and Famcyclovir in the management of Acute Herpes Zoster. MATERIALS AND METHODS: Relevant data were taken from 162 patients with herpes zoster who presented within 72 hours of onset of rash and were randomized into 2 groups of 81 each. The 1st group received Valacyclovir 1gm thrice a day for 7 days while those in the 2nd group received Famcyclovir 500 mg thrice a day for 7 days respectively and evaluated at the end of each week upto 6 weeks period and examined for full crusting of lesions, complete healing of the lesion and loss of acute pain (visual analogue scale scores for pain. Safety assessment was based on adverse effects. RESULTS: The intent to treat analysis (162 Pts showed that valacyclovir for 7 days significantly accelerated the resolution of pain in Herpes zoster pts (P=0.00014 compared with famcyclovir; median pain duration were 21 and 22 days respectively. There was no difference between treatments in time taken for healing of lesions. Adverse effects like nausea, vomiting, diarrhoea and headache were commonly reported in both groups. Valacyclovir was found to be statistically superior over Famcyclovir in terms of G.I adverse effects. Compliance was also better with Valacyclovir. CONCLUSION: Oral Valacyclovir administered three times daily for 7 days during acute zoster infection offers significant benefit by providing a well-tolerated, cost effective and accelerated rate of resolution of pain and maintains the favorable safety profile compared to oral Famcyclovir.

  8. What is Learned from Longitudinal Studies of Advertising and Youth Drinking and Smoking? A Critical Assessment

    Directory of Open Access Journals (Sweden)

    Jon P. Nelson

    2010-03-01

    Full Text Available This paper assesses the methodology employed in longitudinal studies of advertising and youth drinking and smoking behaviors. These studies often are given a causal interpretation in the psychology and public health literatures. Four issues are examined from the perspective of econometrics. First, specification and validation of empirical models. Second, empirical issues associated with measures of advertising receptivity and exposure. Third, potential endogeneity of receptivity and exposure variables. Fourth, sample selection bias in baseline and follow-up surveys. Longitudinal studies reviewed include 20 studies of youth drinking and 26 studies of youth smoking. Substantial shortcomings are found in the studies, which preclude a causal interpretation.

  9. Profiling postgraduate workplace-based assessment implementation in Ireland: a retrospective cohort study.

    Science.gov (United States)

    Barrett, Aileen; Galvin, Rose; Steinert, Yvonne; Scherpbier, Albert; O'Shaughnessy, Ann; Walsh, Gillian; Horgan, Mary

    2016-01-01

    In 2010, workplace-based assessment (WBA) was formally integrated as a method of formative trainee assessment into 29 basic and higher specialist medical training (BST/HST) programmes in six postgraduate training bodies in Ireland. The aim of this study is to explore how WBA is being implemented and to examine if WBA is being used formatively as originally intended. A retrospective cohort study was conducted and approved by the institution's Research Ethics Committee. A profile of WBA requirements was obtained from 29 training programme curricula. A data extraction tool was developed to extract anonymous data, including written feedback and timing of assessments, from Year 1 and 2 trainee ePortfolios in 2012-2013. Data were independently quality assessed and compared to the reference standard number of assessments mandated annually where relevant. All 29 training programmes mandated the inclusion of at least one case-based discussion (max = 5; range 1-5). All except two non-clinical programmes (93 %) required at least two mini-Clinical Evaluation Exercise assessments per year and Direct Observation of Procedural Skills assessments were mandated in 27 training programmes over the course of the programme. WBA data were extracted from 50 % of randomly selected BST ePortfolios in four programmes (n = 142) and 70 % of HST ePortfolios (n = 115) in 21 programmes registered for 2012-2013. Four programmes did not have an eligible trainee for that academic year. In total, 1142 WBAs were analysed. A total of 164 trainees (63.8 %) had completed at least one WBA. The average number of WBAs completed by HST trainees was 7.75 (SD 5.8; 95 % CI 6.5-8.9; range 1-34). BST trainees completed an average of 6.1 assessments (SD 9.3; 95 % CI 4.01-8.19; range 1-76). Feedback-of varied length and quality-was provided on 44.9 % of assessments. The majority of WBAs were completed in the second half of the year. There is significant heterogeneity with respect to the frequency and

  10. Reporting of Human Genome Epidemiology (HuGE association studies: An empirical assessment

    Directory of Open Access Journals (Sweden)

    Gwinn Marta

    2008-05-01

    Full Text Available Abstract Background Several thousand human genome epidemiology association studies are published every year investigating the relationship between common genetic variants and diverse phenotypes. Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies. Methods Articles were randomly selected from a continuously updated database of human genome epidemiology association studies to be representative of genetic epidemiology literature. The main analysis evaluated 315 articles published in 2001–2003. For a comparative update, we evaluated 28 more recent articles published in 2006, focusing on issues that were poorly reported in 2001–2003. Results During both time periods, most studies comprised relatively small study populations and examined one or more genetic variants within a single gene. Articles were inconsistent in reporting the data needed to assess selection bias and the methods used to minimize misclassification (of the genotype, outcome, and environmental exposure or to identify population stratification. Statistical power, the use of unrelated study participants, and the use of replicate samples were reported more often in articles published during 2006 when compared with the earlier sample. Conclusion We conclude that many items needed to assess error and bias in human genome epidemiology association studies are not consistently reported. Although some improvements were seen over time, reporting guidelines and online supplemental material may help enhance the transparency of this literature.

  11. Indoor air assessment: A review of indoor-air-quality risk characterization studies

    International Nuclear Information System (INIS)

    Risk assessment methodologies provide a mechanism for incorporating scientific evidence and judgments into the risk management decision process. A risk characterization framework has been developed to provide a systematic approach for analysis and presentation of risk characterization study results. The framework was used as a tool to review published studies that provide quantitative risk estimates associated with exposure to indoor air pollutants. Comparisons of both the methods and the resulting risk estimates are presented. Critical assumptions concerning risk estimates and exposure estimates for each study are recorded on the framework. Fourteen risk characterization studies were reviewed include three studies for radon, six for environmental tobacco smoke, three for volatile organics, one for formaldehyde only, and one for asbestos. The quality and rigor of analysis varied greatly among the studies reviewed. Some of the studies clearly state that they are intended to be preliminary analyses or screening studies, others are reported as sensitivity analyses, and others are detailed risk assessments. Studies which are technically rigorous in some risk components (e.g., dose-response relationships) are often less rigorous in other components (e.g. exposure assessment)

  12. Qualichem in vivo: A tool for assessing the quality of in vivo studies and its application for bisphenol A

    NARCIS (Netherlands)

    Maxim, Laura; Van Der Sluijs, Jeroen P.

    2014-01-01

    In regulatory toxicology, quality assessment of in vivo studies is a critical step for assessing chemical risks. It is crucial for preserving public health studies that are considered suitable for regulating chemicals are robust. Current procedures for conducting quality assessments in safety agenci

  13. Bayesian hierarchical models combining different study types and adjusting for covariate imbalances: a simulation study to assess model performance.

    Directory of Open Access Journals (Sweden)

    C Elizabeth McCarron

    Full Text Available BACKGROUND: Bayesian hierarchical models have been proposed to combine evidence from different types of study designs. However, when combining evidence from randomised and non-randomised controlled studies, imbalances in patient characteristics between study arms may bias the results. The objective of this study was to assess the performance of a proposed Bayesian approach to adjust for imbalances in patient level covariates when combining evidence from both types of study designs. METHODOLOGY/PRINCIPAL FINDINGS: Simulation techniques, in which the truth is known, were used to generate sets of data for randomised and non-randomised studies. Covariate imbalances between study arms were introduced in the non-randomised studies. The performance of the Bayesian hierarchical model adjusted for imbalances was assessed in terms of bias. The data were also modelled using three other Bayesian approaches for synthesising evidence from randomised and non-randomised studies. The simulations considered six scenarios aimed at assessing the sensitivity of the results to changes in the impact of the imbalances and the relative number and size of studies of each type. For all six scenarios considered, the Bayesian hierarchical model adjusted for differences within studies gave results that were unbiased and closest to the true value compared to the other models. CONCLUSIONS/SIGNIFICANCE: Where informed health care decision making requires the synthesis of evidence from randomised and non-randomised study designs, the proposed hierarchical Bayesian method adjusted for differences in patient characteristics between study arms may facilitate the optimal use of all available evidence leading to unbiased results compared to unadjusted analyses.

  14. A preliminary study on application of risk assessment to seismic risk management of nuclear fuel facilities

    International Nuclear Information System (INIS)

    Studies on risk-informed safety regulation and/or management of nuclear installations are being carried out world widely on the background of progress in development of probabilistic safety assessment (PSA) methodology and its application. The study on PSA methodology and application is on going at the Japan Atomic Energy Agency. A PSA methodology has been developed for MOX fuel fabrication facilities in this study. A preliminary study on application of risk assessment to examine seismic risk management of nuclear fuel facilities has been also carried out as one of those research activities. A simple approach of assessing risk has been investigated based on the analytical policy so called 'graded approach' in which detail of risk analysis can be changed corresponding with the level of potential risk of facilities. Following three issues have been studied with a sample case of uranium fuel fabrication facility. (1) Approach to application of Seismic PSA to examine reasonable practicable seismic risk management, (2) Assessing method of seismic induced accident scenarios and their consequence, (3) Applicable safety level to evaluate the effectiveness of risk management. (author)

  15. Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area

    Institute of Scientific and Technical Information of China (English)

    Tang Chuan; Zhu Jing; Liang Jingtao

    2009-01-01

    The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area. A numerical rating system was applied to five factors that contribute to slope instability. Factors such as lithology, topography, streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment. A final map is provided to show areas of low,medium, and high landslide susceptibility. Areas identified as having high landslide susceptibility were located in the central,northeastern, and far south regions of the study area. The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction. The maps may also be used as a basis for landslide risk management in the study area.

  16. Assessment of modern methods of human factor reliability analysis in PSA studies

    International Nuclear Information System (INIS)

    The report is structured as follows: Classical terms and objects (Probabilistic safety assessment as a framework for human reliability assessment; Human failure within the PSA model; Basic types of operator failure modelled in a PSA study and analyzed by HRA methods; Qualitative analysis of human reliability; Quantitative analysis of human reliability used; Process of analysis of nuclear reactor operator reliability in a PSA study); New terms and objects (Analysis of dependences; Errors of omission; Errors of commission; Error forcing context); and Overview and brief assessment of human reliability analysis (Basic characteristics of the methods; Assets and drawbacks of the use of each of HRA method; History and prospects of the use of the methods). (P.A.)

  17. Web-based Peer Assessment: A Case Study with Civil Engineering Students

    Directory of Open Access Journals (Sweden)

    Gonçalo Cruz

    2013-02-01

    Full Text Available Peer-assessed online collaborative writing is of growing importance for higher education. Based on the quantitative and qualitative analysis of collected data, this work presents the results of a case study in a graduate civil engineering course at the University of Trás-os-Montes e Alto Douro, Vila Real, Portugal. After an overall presentation of the learning activity, it examines students’ attitudes towards web-based peer assessment and identifies which factors are related to students’ use and appreciation of feedback. In addition, an analysis of the type of feedback is presented in an attempt to evaluate students’  written communication skills. The results of this study provide indications on how to improve the design and implementation of future web-based peer assessment tasks and raise questions on the effectiveness of peer/teacher grading in the use of feedback.

  18. Environmental health risk assessment of ambient lead levels in Lisbon, Portugal: A full chain study approach

    DEFF Research Database (Denmark)

    Casimiro, E.; Philippe Ciffroy, P.; Serpa, P.;

    2011-01-01

    to calculate the Pb levels in the various body systems. Our results showed a low health risk from Pb exposures. It also identified that ingestion of leafy vegetables (i.e. lettuce, cabbage, and spinach) and fruits contribute the most to total Pb blood levels. This full chain assessment approach of the 2FUN......The multi-causality interactions between environment and health are complex and call for an integrated multidisciplinary study approach. Emerging computational toxicology tools that link toxicology, chemistry, environmental sciences, biostatistics, and computer sciences are proving to be very...... useful for integrated full-chain human health risk assessments. In this study we use a newly developed computational tool – the 2FUN player to conduct a full-chain assessment combining measured ambient air lead concentrations with multi-media modelling and PBPK simulations to estimate the health risks...

  19. Biomass Assessment. Assessment of global biomass potentials and their links to food, water, biodiversity, energy demand and economy. Inventory and analysis of existing studies. Supporting document

    International Nuclear Information System (INIS)

    This supporting document contains the result from the inventory phase of the biomass assessment of global biomass potentials and their links to food, water, biodiversity, energy demand and economy. This study provides a comprehensive assessment of global biomass potential estimates, focusing on the various factors affecting these potentials, such as food supplies, water use, biodiversity, energy demands and agro-economics

  20. Water Footprint and Life Cycle Assessment as approaches to assess potential impacts of products on water consumption: Key learning points from pilot studies on tea and margarine

    NARCIS (Netherlands)

    Jefferies, D.; Muñoz, I.; Hodges, J.; King, V.J.; Aldaya, M.M.; Ercin, A.E.; Milá i Canals, L.; Hoekstra, A.Y.

    2012-01-01

    Water accounting and environmental impact assessment across the product's life cycle is gaining prominence. This paper presents two case studies of applying the Life Cycle Assessment (LCA) and Water Footprint (WF) approaches to tea and margarine. The WF, excluding grey water, of a carton of 50 g tea

  1. A Study of the Utility of Results from the 1992 Trial State Assessment (TSA) in Reading for State-Level Administrators of Assessment.

    Science.gov (United States)

    Bullock, Cheryl Davis; DeStefano, Lizanne

    1998-01-01

    The usefulness of the 1992 TSA in reading was studied using interviews from 26 state directors of assessment. Perceptions about TSA credibility and orientation of test components and current use of TSA results were examined. The directors suggested involving more teachers in assessment, modifying descriptors, disseminating results quicker, and…

  2. International Code Assessment and Applications Program: Summary of code assessment studies concerning RELAP5/MOD2, RELAP5/MOD3, and TRAC-B. International Agreement Report

    Energy Technology Data Exchange (ETDEWEB)

    Schultz, R.R. [EG and G Idaho, Inc., Idaho Falls, ID (United States)

    1993-12-01

    Members of the International Code Assessment Program (ICAP) have assessed the US Nuclear Regulatory Commission (USNRC) advanced thermal-hydraulic codes over the past few years in a concerted effort to identify deficiencies, to define user guidelines, and to determine the state of each code. The results of sixty-two code assessment reviews, conducted at INEL, are summarized. Code deficiencies are discussed and user recommended nodalizations investigated during the course of conducting the assessment studies and reviews are listed. All the work that is summarized was done using the RELAP5/MOD2, RELAP5/MOD3, and TRAC-B codes.

  3. Measuring Primary Students' Graph Interpretation Skills Via a Performance Assessment: A case study in instrument development

    Science.gov (United States)

    Peterman, Karen; Cranston, Kayla A.; Pryor, Marie; Kermish-Allen, Ruth

    2015-11-01

    This case study was conducted within the context of a place-based education project that was implemented with primary school students in the USA. The authors and participating teachers created a performance assessment of standards-aligned tasks to examine 6-10-year-old students' graph interpretation skills as part of an exploratory research project. Fifty-five students participated in a performance assessment interview at the beginning and end of a place-based investigation. Two forms of the assessment were created and counterbalanced within class at pre and post. In situ scoring was conducted such that responses were scored as correct versus incorrect during the assessment's administration. Criterion validity analysis demonstrated an age-level progression in student scores. Tests of discriminant validity showed that the instrument detected variability in interpretation skills across each of three graph types (line, bar, dot plot). Convergent validity was established by correlating in situ scores with those from the Graph Interpretation Scoring Rubric. Students' proficiency with interpreting different types of graphs matched expectations based on age and the standards-based progression of graphs across primary school grades. The assessment tasks were also effective at detecting pre-post gains in students' interpretation of line graphs and dot plots after the place-based project. The results of the case study are discussed in relation to the common challenges associated with performance assessment. Implications are presented in relation to the need for authentic and performance-based instructional and assessment tasks to respond to the Common Core State Standards and the Next Generation Science Standards.

  4. Combining Learning and Assessment in Assessment-Based Gaming Environments: A Case Study from a New York City School

    Science.gov (United States)

    Zapata-Rivera, Diego; VanWinkle, Waverely; Doyle, Bryan; Buteux, Alyssa; Bauer, Malcolm

    2009-01-01

    Purpose: The purpose of this paper is to propose and demonstrate an evidence-based scenario design framework for assessment-based computer games. Design/methodology/approach: The evidence-based scenario design framework is presented and demonstrated by using BELLA, a new assessment-based gaming environment aimed at supporting student learning of…

  5. Building an Assessment Argument to Design and Use Next Generation Science Assessments in Efficacy Studies of Curriculum Interventions

    Science.gov (United States)

    DeBarger, Angela Haydel; Penuel, William R.; Harris, Christopher J.; Kennedy, Cathleen A.

    2016-01-01

    Evaluators must employ research designs that generate compelling evidence related to the worth or value of programs, of which assessment data often play a critical role. This article focuses on assessment design in the context of evaluation. It describes the process of using the Framework for K-12 Science Education and Next Generation Science…

  6. A STUDY OF DIAGNOSTIC ACCURACY AND UTILITY OF ULTRASOUND IN THE ASSESSMENT OF BILIARY STENT

    Directory of Open Access Journals (Sweden)

    Prashant U

    2015-09-01

    Full Text Available Ultrasound is cheap , easily available imaging modality which is useful in detection of stent within the biliary tree , dilatation of biliary tree and in assessment of complications after ERCP. AIMS AND OBJECTIVE: Our study aims at to statistic ally assess the diagnostic accuracy and utility of ultrasound in assessment of biliary stent. MATERIAL AND METHOD S : Total 221 patients from gastroenterology department were evaluated by ultrasound abdomen examination using Philips HD 11XE ultrasound scanne r. Post ERCP clinical details were obtained. X - ray abdomen done in all cases with ERCP is done wherever required. RESULT: In our study we found following measures of diagnostic accuracy in detection of biliary stent. Sensitivity 77.27% , Specificity 94.59% , Accuracy 85.97% , Positive predictive value 93.40% , Negative predictive value 80.76% , Positive likelihood ratio 14.29 , Negative likelihood ratio 0.24 , Diagnostic odds ratio 59.50. Twenty cases showed biliary dilatation in presence of CBD stent. Out of thes e 4 cases showed presence of upper end of stent in tumor mass while in rest cases it was in dilated biliary tree. Post ERCP complications were noted in 11 cases. CONCLUSION: Ultrasound is a reliable , noninvasive , nonradiative imaging modality to assess presence of biliary stent , biliary dilatation in presence of stent and to assess tumor status and post ERCP complications. Hence we recommend the use of follow up ultrasound after ERCP procedure.

  7. Deep assessment: an exploratory study of game-based, multimodal learning in Epidemic

    Directory of Open Access Journals (Sweden)

    Jennifer Jenson

    2016-03-01

    Full Text Available n this study, we examine what and how intermediate age students learned from playing in a health-focused game-based digital learning environment, Epidemic. Epidemic is a playful interactive environment designed to deliver factual knowledge, invite critical understanding, and encourage effective self-care practices in dealing with viral contagious diseases, using a social networking interface to integrate both serious games and game-like multimodal design projects. Epidemic invites a playful approach to its deadly serious core concern – communicable disease – in order to see what happens when students are encouraged to critically approach information from multiple or contradictory perspectives. To identify what participants learned while interacting within Epidemic, we deployed two instructional and assessment models, noting the differences each instructional approach could potentially make, and what approach to assessment might help us evaluate game-based learning. We found that each approach provided importantly different perspectives on what and how students learned, and on the very meaning of student success. Recognizing that traditional assessment tools based in print-cultural literacy may prove increasingly ill-suited for assessing emergent multimodal literacies in game-based learning environments, this study seeks to contribute to a growing body of work on the development of novel assessments for learning.

  8. Results of the Weeks Island Strategic Petroleum Reserve Oil Leak Risk Assessment Study

    International Nuclear Information System (INIS)

    This study evaluated multiple, long-term environmental oil-contamination risk scenarios that could result from the potential leakage of UP to 1.5 million barrels of crude oil entombed in the Weeks Island SPR mine following site decommissioning and abandonment, and up to 100 years thereafter. This risk assessment also provides continuity with similar risk evaluations performed earlier and documented in the 1995 DOE Environmental Assessment for Decommissioning the Strategic Petroleum Reserve Weeks Island Facility (EA). This current study was requested by the DOE to help them determine if their previous Finding of No Significant Impact (FONSI), in the EA, is still valid or needs to be rescinded. Based on the calculated environmental risk results (in terms of clean-up and remediation expenses) presented in this risk assessment, including the calculated average likelihoods of oil release and potential oil-leakage volumes, none of the evaluated risk events would appear to satisfy the definition of significant environmental impact in National Environmental Policy Act (NEPA) terminology. The DOE may combine these current results with their earlier evaluations and interpretations in the 1995 EA in order to assess whether the existing FONSI is still accurate, acceptable, and valid. However, from a risk evaluation standpoint, the assessment of impacts appears to be the same whether only 10,000 to 30,000 barrels of crude oil (as considered in the 1995 EA), or up to 1.5 million barrels of oil (as considered herein) are abandoned in the Weeks Island SPR facility

  9. Assessment of stereoscopic optic disc images using an autostereoscopic screen – experimental study

    Directory of Open Access Journals (Sweden)

    Vaideanu Daniella

    2008-07-01

    Full Text Available Abstract Background Stereoscopic assessment of the optic disc morphology is an important part of the care of patients with glaucoma. The aim of this study was to assess stereoviewing of stereoscopic optic disc images using an example of the new technology of autostereoscopic screens compared to the liquid shutter goggles. Methods Independent assessment of glaucomatous disc characteristics and measurement of optic disc and cup parameters whilst using either an autostereoscopic screen or liquid crystal shutter goggles synchronized with a view switching display. The main outcome measures were inter-modality agreements between the two used modalities as evaluated by the weighted kappa test and Bland Altman plots. Results Inter-modality agreement for measuring optic disc parameters was good [Average kappa coefficient for vertical Cup/Disc ratio was 0.78 (95% CI 0.62–0.91 and 0.81 (95% CI 0.6–0.92 for observer 1 and 2 respectively]. Agreement between modalities for assessing optic disc characteristics for glaucoma on a five-point scale was very good with a kappa value of 0.97. Conclusion This study compared two different methods of stereo viewing. The results of assessment of the different optic disc and cup parameters were comparable using an example of the newly developing autostereoscopic display technologies as compared to the shutter goggles system used. The Inter-modality agreement was high. This new technology carries potential clinical usability benefits in different areas of ophthalmic practice.

  10. Alcohol email assessment and feedback study dismantling effectiveness for university students (AMADEUS-1: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    McCambridge Jim

    2012-07-01

    Full Text Available Abstract Background Alcohol causes huge problems for population health and for society, which require interventions with individuals as well as populations to prevent and reduce harms. Brief interventions can be effective and increasingly take advantage of the internet to reach high-risk groups such as students. The research literature on the effectiveness of online interventions is developing rapidly and is confronted by methodological challenges common to other areas of e-health including attrition and assessment reactivity and in the design of control conditions. Methods/design The study aim is to evaluate the effectiveness of a brief online intervention, employing a randomized controlled trial (RCT design that takes account of baseline assessment reactivity, and other possible effects of the research process. Outcomes will be evaluated after 3 months both among student populations as a whole including for a randomized no contact control group and among those who are risky drinkers randomized to brief assessment and feedback (routine practice or to brief assessment only. A three-arm parallel groups trial will also allow exploration of the magnitude of the feedback and assessment component effects. The trial will be undertaken simultaneously in 2 universities randomizing approximately 15,300 students who will all be blinded to trial participation. All participants will be offered routine practice intervention at the end of the study. Discussion This trial informs the development of routine service delivery in Swedish universities and more broadly contributes a new approach to the study of the effectiveness of online interventions in student populations, with relevance to behaviors other than alcohol consumption. The use of blinding and deception in this study raise ethical issues that warrant further attention. Trial registration ISRCTN28328154

  11. 75 FR 33324 - MMS Information Collection Activity: 1010-NEW, Study of Sharing To Assess Community Resilience...

    Science.gov (United States)

    2010-06-11

    ... Federal Register notice (75 FR 1648) announcing that we would submit this ICR to OMB for approval. The... Minerals Management Service MMS Information Collection Activity: 1010--NEW, Study of Sharing To Assess... collection (1010--NEW). SUMMARY: To comply with the Paperwork Reduction Act of 1995 (PRA), we are...

  12. A Study on Critical Thinking Assessment System of College English Writing

    Science.gov (United States)

    Dong, Tian; Yue, Lu

    2015-01-01

    This research attempts to discuss the validity of introducing the evaluation of students' critical thinking skills (CTS) into the assessment system of college English writing through an empirical study. In this paper, 30 College English Test Band 4 (CET-4) writing samples were collected and analyzed. Students' CTS and the final scores of collected…

  13. Comparative study of anal acoustic reflectometry and anal manometry in the assessment of faecal incontinence

    DEFF Research Database (Denmark)

    Hornung, B R; Mitchell, P J; Carlson, G L;

    2012-01-01

    Anal acoustic reflectometry (AAR) is a reproducible technique providing a novel physiological assessment of anal sphincter function. It may have advantages over conventional anal manometry. The aims of this study were to determine the ability of AAR and anal manometry to identify changes in anal...

  14. Evaluability Assessment Thesis and Dissertation Studies in Graduate Professional Degree Programs

    Science.gov (United States)

    Walser, Tamara M.; Trevisan, Michael S.

    2016-01-01

    Evaluability assessment (EA) has potential as a design option for thesis and dissertation studies, serving as a practical training experience for both technical and nontechnical evaluation skills. Based on a content review of a sample of EA theses and dissertations from graduate professional degree programs, the authors of this article found that…

  15. Preferences for Deep-Surface Learning: A Vocational Education Case Study Using a Multimedia Assessment Activity

    Science.gov (United States)

    Hamm, Simon; Robertson, Ian

    2010-01-01

    This research tests the proposition that the integration of a multimedia assessment activity into a Diploma of Events Management program promotes a deep learning approach. Firstly, learners' preferences for deep or surface learning were evaluated using the revised two-factor Study Process Questionnaire. Secondly, after completion of an assessment…

  16. The Effectiveness of Coursework Assessment in Mathematics Service Courses--Studies at Two Universities.

    Science.gov (United States)

    Jackman, Susan; Goldfinch, Judy; Searl, John

    2001-01-01

    Describes the introduction and evaluation of the effectiveness of a single group project given at a new university, and 10 individual tasks at an ancient university, to devise appropriate and relevant assessments for first-year service mathematics courses for science and engineering. Studies the effects of these tasks on attitudes toward…

  17. The diesel exhaust in miners study: I. Overview of the exposure assessment process.

    NARCIS (Netherlands)

    Stewart, P.A.; Coble, J.B.; Vermeulen, R.; Schleiff, P.; Blair, A.; Lubin, J.; Attfield, M.; Silverman, D.T.

    2010-01-01

    This report provides an overview of the exposure assessment process for an epidemiologic study that investigated mortality, with a special focus on lung cancer, associated with diesel exhaust (DE) exposure among miners. Details of several components are provided in four other reports. A major challe

  18. Comparative assessment of predictions in ungauged basins – Part 2: Flood and low flow studies

    Directory of Open Access Journals (Sweden)

    M. Sivapalan

    2013-01-01

    Full Text Available The objective of this paper is to assess the performance of methods that predict low flows and flood runoff in ungauged catchments. The aim is to learn from the similarities and differences between catchments in different places, and to interpret the differences in performance in terms of the underlying climate-landscape controls. The assessment is performed at two levels. The Level 1 assessment is a meta-analysis of 14 low flow prediction studies reported in the literature involving 3112 catchments, and 20 flood prediction studies involving 3023 catchments. The Level 2 assessment consists of a more focused and detailed analysis of individual basins from selected studies from Level 1 in terms of how the leave-one-out cross-validation performance depends on climate and catchment characteristics as well as on the regionalisation method. The results indicate that both flood and low flow predictions in ungauged catchments tend to be less accurate in arid than in humid climates and more accurate in large than in small catchments. There is also a tendency towards a somewhat lower performance of regressions than other methods in those studies that apply different methods in the same region, while geostatistical methods tend to perform better than other methods. Of the various flood regionalisation approaches, index methods show significantly lower performances in arid catchments than regression methods or geostatistical methods. For low flow regionalisation, regional regressions are generally better than global regressions.

  19. Comparative assessment of predictions in ungauged basins – Part 2: Flood and low flow studies

    Directory of Open Access Journals (Sweden)

    J. L. Salinas

    2013-07-01

    Full Text Available The objective of this paper is to assess the performance of methods that predict low flows and flood runoff in ungauged catchments. The aim is to learn from the similarities and differences between catchments in different places, and to interpret the differences in performance in terms of the underlying climate-landscape controls. The assessment is performed at two levels. The Level 1 assessment is a meta-analysis of 14 low flow prediction studies reported in the literature involving 3112 catchments, and 20 flood prediction studies involving 3023 catchments. The Level 2 assessment consists of a more focused and detailed analysis of individual basins from selected studies from Level 1 in terms of how the leave-one-out cross-validation performance depends on climate and catchment characteristics as well as on the regionalisation method. The results indicate that both flood and low flow predictions in ungauged catchments tend to be less accurate in arid than in humid climates and more accurate in large than in small catchments. There is also a tendency towards a somewhat lower performance of regressions than other methods in those studies that apply different methods in the same region, while geostatistical methods tend to perform better than other methods. Of the various flood regionalisation approaches, index methods show significantly lower performance in arid catchments than regression methods or geostatistical methods. For low flow regionalisation, regional regressions are generally better than global regressions.

  20. Assessing Mobile Learning Readiness in Saudi Arabia Higher Education: An Empirical Study

    Science.gov (United States)

    Aljuaid, Nada Mansour F.; Alzahrani, Mohammed Ali Rajab; Islam, A. Y. M. Atiquil

    2014-01-01

    Mobile learning has been introduced for quite some time now at Taif University. However, there is no research conducted to measure the readiness of mobile learning within its context. As such, the aim of this study is to assess the lecturers' readiness for mobile learning in higher education in terms of perceived usefulness and perceived ease of…

  1. Does Participation in Citizen Science Improve Scientific Literacy? A Study to Compare Assessment Methods

    Science.gov (United States)

    Cronje, Ruth; Rohlinger, Spencer; Crall, Alycia; Newman, Greg

    2011-01-01

    This study investigated the use of a contextually sensitive instrument to assess the effect of invasive species monitoring training on the scientific literacy of citizen volunteers. The authors measured scientific literacy scores before and after 57 citizens participated in a 2-day event to learn to monitor invasive species with an instrument…

  2. Molecular effects of isoflavone supplementation : human intervention studies and quantitative models for risk assessment

    NARCIS (Netherlands)

    Velpen, van der V.

    2014-01-01

    Background: Risk assessment can potentially be improved by closely linked experiments in the disciplines of epidemiology and toxicology. This was explored for isoflavones in a case study. For isoflavones potential beneficial health effects have been suggested, but discussions on their safety are ong

  3. Assessment of Greek University Students' Counselling Needs and Attitudes: An Exploratory Study

    Science.gov (United States)

    Giovazolias, Theodoros; Leontopoulou, Sophia; Triliva, Sophia

    2010-01-01

    The present study is concerned with an exploration of counselling needs of students at two Greek universities as well as their attitudes to utilizing a university counselling centre. The sample consisted of 312 students who completed a Greek version of the Rutgers Needs Assessment Questionnaire as well as a subscale on Attitudes towards the…

  4. An Assessment of Intervention Fidelity in Published Social Work Intervention Research Studies

    Science.gov (United States)

    Corley, Nicole A.; Kim, Irang

    2016-01-01

    Objectives: Intervention fidelity is a critical strategy to help advance the usefulness and integrity of social work research. This study assessed the extent to which a selected sample of published social work intervention researchers reported its intervention protocols. Methods: Six core social work journals were reviewed in this analysis. The…

  5. Perceptions of Effectiveness, Fairness and Feedback of Assessment Methods: A Study in Higher Education

    Science.gov (United States)

    Flores, Maria Assunção; Veiga Simão, Ana Margarida; Barros, Alexandra; Pereira, Diana

    2015-01-01

    This paper draws upon a broader piece of research aimed at investigating assessment in higher education. It focuses upon the perceptions of undergraduates about issues of effectiveness, fairness and feedback, particularly in regard to the so-called learner-centred methods. In total, 378 undergraduate students participated in the study at the…

  6. Chair Report Consultancy Meeting on Nuclear Security Assessment Methodologies (NUSAM) Transport Case Study Working Group

    Energy Technology Data Exchange (ETDEWEB)

    Shull, Doug [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-08-19

    The purpose of the consultancy assignment was to (i) apply the NUSAM assessment methods to hypothetical transport security table top exercise (TTX) analyses and (ii) document its results to working materials of NUSAM case study on transport. A number of working group observations, using the results of TTX methodologies, are noted in the report.

  7. Form follows function? Proposing a blueprint for ecosystem service assessments based on reviews and case studies

    NARCIS (Netherlands)

    Seppelt, R.; Fath, B.; Burkhard, B.; Fisher, J.L.; Grêt-Regamey, A.; Lautenbach, S.; Pert, P.; Hotes, S.; Spangenberg, J.; Verburg, P.H.; Oudenhoven, van A.P.E.

    2012-01-01

    Ecosystem service assessments (ESA) hold the promise of supporting the quantification and valuation of human appropriation of nature and its goods and services. The concept has taken flight with the number of studies published on the topic increasing rapidly. This development, and the variation of d

  8. An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios (External Review Draft)

    Science.gov (United States)

    EPA has released an external review draft entitled, An Exploratory Study: Assessment of Modeled Dioxin Exposure in Ceramic Art Studios(External Review Draft). The public comment period and the external peer-review workshop are separate processes that provide opportunities ...

  9. What about Language while Equitably Assessing Science?: Case Studies of Preservice Teachers' Evolving Expertise

    Science.gov (United States)

    Lyon, Edward G.

    2013-01-01

    The three case studies, drawing on qualitative analysis of surveys, interviews, program artifacts, and classroom observation, describe secondary science preservice teachers' evolving expertise at providing opportunities for linguistically diverse students to learn and demonstrate what they have learned (i.e., equitable assessment). The teachers…

  10. Intonation Features of the Expression of Emotions in Spanish: Preliminary Study for a Prosody Assessment Procedure

    Science.gov (United States)

    Martinez-Castilla, Pastora; Peppe, Susan

    2008-01-01

    This study aimed to find out what intonation features reliably represent the emotions of "liking" as opposed to "disliking" in the Spanish language, with a view to designing a prosody assessment procedure for use with children with speech and language disorders. 18 intonationally different prosodic realisations (tokens) of one word (limon) were…

  11. Capturing doping attitudes by self-report declarations and implicit assessment: A methodology study

    OpenAIRE

    Aidman Eugene V; Petróczi Andrea; Nepusz Tamás

    2008-01-01

    Abstract Background Understanding athletes' attitudes and behavioural intentions towards performance enhancement is critical to informing anti-doping intervention strategies. Capturing the complexity of these attitudes beyond verbal declarations requires indirect methods. This pilot study was aimed at developing and validating a method to assess implicit doping attitudes using an Implicit Associations Test (IAT) approach. Methods The conventional IAT evaluation task (categorising 'good' and '...

  12. Daily Emotional Dynamics in Depressed Youth: A Cell Phone Ecological Momentary Assessment Study

    Science.gov (United States)

    Silk, Jennifer S.; Forbes, Erika E.; Whalen, Diana J.; Jakubcak, Jennifer L.; Thompson, Wesley K.; Ryan, Neal D.; Axelson, David A.; Birmaher, Boris; Dahl, Ronald E.

    2011-01-01

    This study used a new cell phone ecological momentary assessment approach to investigate daily emotional dynamics in 47 youths with major depressive disorder (MDD) and 32 no-psychopathology controls (CON) (ages 7-17 years). Information about emotional experience in the natural environment was obtained using answer-only cell phones, while MDD…

  13. Mood disorders in everyday life : A systematic review of experience sampling and ecological momentary assessment studies

    NARCIS (Netherlands)

    Aan het Rot, M.; Hogenelst, Koen; Schoevers, R.A.

    2012-01-01

    In the past two decades, the study of mood disorder patients using experience sampling methods (ESM) and ecological momentary assessment (EMA) has yielded important findings. In patients with major depressive disorder (MDD), the dynamics of their everyday mood have been associated with various aspec

  14. Individualizing Elementary General Music Instruction: Case Studies of Assessment and Differentiation

    Science.gov (United States)

    Salvador, Karen

    2011-01-01

    Elementary general music teachers typically teach hundreds of students every week. Each child has individual learning needs due to a variety of factors, such as prior experiences with music, music aptitude, learning style, and personality. The purpose of this qualitative study was to explore ways that experienced teachers used assessments to…

  15. Assessing internet addiction using the parsimonious internet addiction components model—A preliminary study.

    NARCIS (Netherlands)

    Kuss, D.J.; Shorter, G.W.; Rooij, A.J. van; Griffiths, M.D.; Schoenmakers, T.M.

    2014-01-01

    Internet usage has grown exponentially over the last decade. Research indicates that excessive Internet use can lead to symptoms associated with addiction. To date, assessment of potential Internet addiction has varied regarding populations studied and instruments used, making reliable prevalence es

  16. Cumulative versus end-of-course assessment : effects on self-study time and test performance

    NARCIS (Netherlands)

    Kerdijk, Wouter; Cohen-Schotanus, Janke; Mulder, B. Florentine; Muntinghe, Friso L. H.; Tio, Rene A.

    2015-01-01

    ContextStudents tend to postpone preparation for a test until the test is imminent, which raises various risks associated with cramming' behaviours, including that for suboptimal learning. Cumulative assessment utilises spaced testing to stimulate students to study more frequently and to prevent pro

  17. Development of a Health Literacy Assessment for Young Adult College Students: A Pilot Study

    Science.gov (United States)

    Harper, Raquel

    2014-01-01

    Objective: The purpose of this study was to develop a comprehensive health literacy assessment tool for young adult college students. Participants: Participants were 144 undergraduate students. Methods: Two hundred and twenty-nine questions were developed, which were based on concepts identified by the US Department of Health and Human Services,…

  18. Case Study: Optimality Theory and the Assessment and Treatment of Phonological Disorders.

    Science.gov (United States)

    Barlow, Jessica A.

    2001-01-01

    A case study of a 3-year-old with a phonological disorder is used to demonstrate the application of optimality theory to the assessment and treatment. A tutorial of the theory is provided and then several prototypical error patterns evident in the child's productions are analyzed within the framework. (Contains references.) (Author/CR)

  19. Emotional Competencies in Geriatric Nursing: Empirical Evidence from a Computer Based Large Scale Assessment Calibration Study

    Science.gov (United States)

    Kaspar, Roman; Hartig, Johannes

    2016-01-01

    The care of older people was described as involving substantial emotion-related affordances. Scholars in vocational training and nursing disagree whether emotion-related skills could be conceptualized and assessed as a professional competence. Studies on emotion work and empathy regularly neglect the multidimensionality of these phenomena and…

  20. Initiating Self-Assessment Strategies in Novice Physiotherapy Students: A Method Case Study

    Science.gov (United States)

    Young, Catherine

    2013-01-01

    Student self- and peer-assessment strategies ideally are instigated early in programmes for health professionals. This study presents an innovative method of stimulating critical evaluation of clinical skills learned in the practical class setting for first year physiotherapy students. Twice in the semester (beginning and end) students assessed…

  1. Success in the US: Are Cambridge International Assessments Good Preparation for University Study?

    Science.gov (United States)

    Shaw, Stuart; Bailey, Clare

    2011-01-01

    This article focuses on the research being conducted by University of Cambridge International Examinations (Cambridge) to ensure that its international assessments prepare students as well as Advanced Placement and International Baccalaureate for continued studies in colleges and universities. The primary purpose of the research is to highlight…

  2. Assessment of visuospatial neglect in stroke patients using virtual reality: a pilot study.

    NARCIS (Netherlands)

    Jannink, Michiel J.A.; Aznar, Miguel; Kort, de Alexander Cornelis; Vis, van de Wim; Veltink, Peter; Kooij, van der Herman

    2009-01-01

    One of the neuropsychological deficits that can result from a stroke is the neglect phenomenon. Neglect has traditionally been assessed with paper-and-pencil tasks, which are administered within the reaching space of a person. The purpose of this explorative study is to investigate whether it is pos

  3. Studies on the Regional Cerebral Blood Flow in Delayed Carbon Monoxide sequelae using 99mTc-HMPAO

    International Nuclear Information System (INIS)

    8 patients of delayed CO sequelae were evaluated using Brain CT and 99mTc-HMPAO SPECT. The results were as follows; 1) CT findings of delayed CO sequelae were bilateral low density lesion in globus pallidus (1 pt.), diffuse low density in white matter with bilateral low density in white matter (1 pt.), diffuse low density in white matter with bilateral low density in globus pallidus (1 pt.), diffuse low density in white matter with cortical atrophy (1 pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (1 pt.) and normal in 3 pts. 2) 99mTc-HMPAO Brain SPECT findings of delayed CO sequelae were decreased regiona1 cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) 99mTc-HMPAO Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

  4. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

    Science.gov (United States)

    Samuel, Gbeminiyi O; Hoffmann, Sebastian; Wright, Robert A; Lalu, Manoj Mathew; Patlewicz, Grace; Becker, Richard A; DeGeorge, George L; Fergusson, Dean; Hartung, Thomas; Lewis, R Jeffrey; Stephens, Martin L

    2016-01-01

    Assessments of methodological and reporting quality are critical to adequately judging the credibility of a study's conclusions and to gauging its potential reproducibility. To aid those seeking to assess the methodological or reporting quality of studies relevant to toxicology, we conducted a scoping review of the available guidance with respect to four types of studies: in vivo and in vitro, (quantitative) structure-activity relationships ([Q]SARs), physico-chemical, and human observational studies. Our aims were to identify the available guidance in this diverse literature, briefly summarize each document, and distill the common elements of these documents for each study type. In general, we found considerable guidance for in vivo and human studies, but only one paper addressed in vitro studies exclusively. The guidance for (Q)SAR studies and physico-chemical studies was scant but authoritative. There was substantial overlap across guidance documents in the proposed criteria for both methodological and reporting quality. Some guidance documents address toxicology research directly, whereas others address preclinical research generally or clinical research and therefore may not be fully applicable to the toxicology context without some translation. Another challenge is the degree to which assessments of methodological quality in toxicology should focus on risk of bias - as in clinical medicine and healthcare - or be broadened to include other quality measures, such as confirming the identity of test substances prior to exposure. Our review is intended primarily for those in toxicology and risk assessment seeking an entry point into the extensive and diverse literature on methodological and reporting quality applicable to their work. PMID:27039952

  5. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

    Science.gov (United States)

    Samuel, Gbeminiyi O; Hoffmann, Sebastian; Wright, Robert A; Lalu, Manoj Mathew; Patlewicz, Grace; Becker, Richard A; DeGeorge, George L; Fergusson, Dean; Hartung, Thomas; Lewis, R Jeffrey; Stephens, Martin L

    2016-01-01

    Assessments of methodological and reporting quality are critical to adequately judging the credibility of a study's conclusions and to gauging its potential reproducibility. To aid those seeking to assess the methodological or reporting quality of studies relevant to toxicology, we conducted a scoping review of the available guidance with respect to four types of studies: in vivo and in vitro, (quantitative) structure-activity relationships ([Q]SARs), physico-chemical, and human observational studies. Our aims were to identify the available guidance in this diverse literature, briefly summarize each document, and distill the common elements of these documents for each study type. In general, we found considerable guidance for in vivo and human studies, but only one paper addressed in vitro studies exclusively. The guidance for (Q)SAR studies and physico-chemical studies was scant but authoritative. There was substantial overlap across guidance documents in the proposed criteria for both methodological and reporting quality. Some guidance documents address toxicology research directly, whereas others address preclinical research generally or clinical research and therefore may not be fully applicable to the toxicology context without some translation. Another challenge is the degree to which assessments of methodological quality in toxicology should focus on risk of bias - as in clinical medicine and healthcare - or be broadened to include other quality measures, such as confirming the identity of test substances prior to exposure. Our review is intended primarily for those in toxicology and risk assessment seeking an entry point into the extensive and diverse literature on methodological and reporting quality applicable to their work.

  6. Assessing Researcher Interdisciplinarity: A Case Study of the University of Hawaii NASA Astrobiology Institute

    CERN Document Server

    Gowanlock, Michael G

    2012-01-01

    In this study, we combine bibliometric techniques with a machine learning algorithm, the sequential Information Bottleneck, to assess the interdisciplinarity of research produced by the University of Hawaii NASA Astrobiology Institute (UHNAI). In particular, we cluster abstract data to evaluate Thomson Reuters Web of Knowledge subject categories as descriptive labels for astrobiology documents, assess individual researcher interdisciplinarity, and determine where collaboration opportunities might occur. We find that the majority of the UHNAI team is engaged in interdisciplinary research, and suggest that our method could be applied to additional NASA Astrobiology Institute teams in particular, or other interdisciplinary research teams more broadly, to identify and facilitate collaboration opportunities.

  7. Mesocosm soil ecological risk assessment tool for GMO 2nd tier studies

    DEFF Research Database (Denmark)

    D'Annibale, Alessandra; Maraldo, Kristine; Larsen, Thomas;

    Ecological Risk Assessment (ERA) of GMO is basically identical to ERA of chemical substances, when it comes to assessing specific effects of the GMO plant material on the soil ecosystem. The tiered approach always includes the option of studying more complex but still realistic ecosystem level...... effects in 2nd tier caged experimental systems, cf. the new GMO ERA guidance: EFSA Journal 2010; 8(11):1879. We propose to perform a trophic structure analysis, TSA, and include the trophic structure as an ecological endpoint to gain more direct insight into the change in interactions between species, i.e...

  8. Flood Disaster Risk Assessment of Rural Housings — A Case Study of Kouqian Town in China

    OpenAIRE

    Qi Zhang; Jiquan Zhang; Liupeng Jiang; Xingpeng Liu; Zhijun Tong

    2014-01-01

    Floods are a devastating kind of natural disaster. About half of the population in China lives in rural areas. Therefore, it is necessary to assess the flood disaster risk of rural housings. The results are valuable for guiding the rescue and relief goods layout. In this study, we take the severe flood disaster that happened at Kouqian Town in Jilin, China in 2010 as an example to build an risk assessment system for flood disaster on rural housings. Based on the theory of natural disaster ris...

  9. Periodontal and dental effects of surgically assisted rapid maxillary expansion, assessed by using digital study models

    OpenAIRE

    Danilo Furquim Siqueira; Mauricio de Almeida Cardoso; Leopoldino Capelozza Filho; Dov Charles Goldenberg; Mariana dos Santos Fernandes

    2015-01-01

    OBJECTIVE: The present study assessed the maxillary dental arch changes produced by surgically assisted rapid maxillary expansion (SARME). METHODS: Dental casts from 18 patients (mean age of 23.3 years) were obtained at treatment onset (T1), three months after SARME (T2) and 6 months after expansion (T3). The casts were scanned in a 3D scanner (D-250, 3Shape, Copenhagen, Denmark). Maxillary dental arch width, dental crown tipping and height were measured and assessed by ANOVA and Tukey's test...

  10. Molecular effects of isoflavone supplementation : human intervention studies and quantitative models for risk assessment

    OpenAIRE

    Velpen, van der, V.

    2014-01-01

    Background: Risk assessment can potentially be improved by closely linked experiments in the disciplines of epidemiology and toxicology. This was explored for isoflavones in a case study. For isoflavones potential beneficial health effects have been suggested, but discussions on their safety are ongoing as well. Aims and methods: Effects of isoflavone supplements on gene expression were studied in white blood cells (PBMCs) and adipose tissue, among postmenopausal women in two human interventi...

  11. ASSESSMENT OF MERCURY RELEASE FROM DENTAL AMALGAM: AN IN VITRO STUDY

    OpenAIRE

    Shetty Aditya; Hegde Mithra N.; Mathew Tony; Bhat Ganesh

    2013-01-01

    Exposure to mercury from dental amalgam restoration, with possible negative health effects, has generally been considered to occur via either erosion or evaporation directly from the surface of fillings, followed by ingestion. This study aims to assess the mercury release from dental amalgam and provide a basis for comparison between mercury release in oral cavities with single and multiple amalgam restorations at different time intervals. This study was conducted in A.B. Shetty Memorial Inst...

  12. Assessing internet addiction using the parsimonious internet addiction components model—A preliminary study.

    OpenAIRE

    Kuss, D.J.; Shorter, G.W.; Rooij, A.J. van; Griffiths, M.D.; Schoenmakers, T.M.

    2014-01-01

    Internet usage has grown exponentially over the last decade. Research indicates that excessive Internet use can lead to symptoms associated with addiction. To date, assessment of potential Internet addiction has varied regarding populations studied and instruments used, making reliable prevalence estimations difficult. To overcome the present problems a preliminary study was conducted testing a parsimonious Internet addiction components model based on Griffiths’ addiction components (Journal ...

  13. The ORNL Indoor Air Quality Study: Re-cap, Context, and Assessment on Radon

    Energy Technology Data Exchange (ETDEWEB)

    Tonn, Bruce Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rose, Erin M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ternes, Mark P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-10-01

    As part of the retrospective evaluation of the U.S. Department of Energy s low-income Weatherization Assistance Program that was led by Oak Ridge National Laboratory (ORNL), an assessment of the impacts of weatherization on indoor air quality (IAQ) was conducted. This assessment included nearly 500 treatment and control homes across the country. Homes were monitored for carbon monoxide, radon, formaldehyde, temperature and humidity pre- and post-weatherization. This report focuses on the topic of radon and addresses issues not thoroughly discussed in the original IAQ report. The size, scope and rigor of the radon component of the IAQ study are compared to previous studies that assessed the impacts of weatherization on indoor radon levels. It is found that the ORNL study is by far the most extensive study conducted to date, though the ORNL results are consistent with the findings of the other studies. However, the study does have limitations related to its reliance on short-term measurements of radon and inability to attribute changes in radon levels in homes post-weatherization to specific weatherization measures individually or in combination.

  14. A preliminary study for an engineering assessment of a shallow land burial facility in clay

    International Nuclear Information System (INIS)

    This study characterises a notional low-level waste repository site within the Oxford clay belt, provides a conceptual design for a shallow, engineered repository at the site, and presents a rationale of the multiple-barrier design basis in sufficient detail to enable BRE to rehearse an engineering assessment. Parameters are identified which describe the repository's structural integrity, permeability and effectiveness in physical and chemical containment of nuclides by resistance to diffusive and advective transport. Such parameters may be used by the DoE as input for the mathematical modelling of the repository's post-closure performance under various release scenarios, as part of a full radiological assessment. Limitations in the analytical methods and experience base available for such assessments are identified and suggestions are made for future research activities. (author)

  15. PERFORMANCE ASSESSMENT OF PRODUCT DEVELOPMENT PROCESS IN A BUS COMPANY: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Tiago Ribeiro de Araújo

    2014-12-01

    Full Text Available This article aims to examine the application of a method for assessing the performance of the product development process (PDP through the assessment of managerial skills in a bus body industry. A case study was carried out and a PDP method was applied through a questionnaire addressing the PDP management skills according to Dechamps and Nayak (1997 model and validated by Silva (2001 in a bus body company which showed all the features available in the literature on industrial segment. The proposed method provided a way to assess strengths and opportunities for improvement in the company´s PDP allowing the company to focus on its efforts in actions to solve deficiencies on critical points and having continuous improvement for consolidation of the identified strengths.

  16. Life Cycle Assessment Studies of Chemical and Biochemical Processes through the new LCSoft Software-tool

    DEFF Research Database (Denmark)

    Supawanich, Perapong; Malakul, Pomthong; Gani, Rafiqul

    2015-01-01

    Life Cycle Assessment or LCA is an effective tool for quantifying the potential environmental impacts of products, processes, or services in order to support the selection making of desired products and/or processes from different alternatives. For more sustainable process designs, technical requ...... LCI assessment results. The fourth task has been added to validate and improve LCSoft by testing it against several case studies and compare the assessment results with other available tools....... requirements have to be evaluated together with environmental and economic aspects. The LCSoft software-tool has been developed to perform LCA as a stand-alone tool as well as integrated with other process design tools such as process simulation, economic analysis (ECON), and sustainable process design...

  17. AHP in Assessing Performance of Diploma Institutes – A Case Study

    Directory of Open Access Journals (Sweden)

    Dr. Sujit Kumar Goshal

    2012-04-01

    Full Text Available Present paper shows application of Analytical Hierarchy Process (AHP as potential tool in decision making in assessing performance of diploma institutes. Parameters for assessing diploma level institutes are used as example. A hierarchical structure is framed for the parameters and the diploma institutes from where feedback received against the parameters for this study. By applying the AHP, the parameters can be prioritized and a descending order list of diploma institutes can be made in order to identify the best performing institutes. A sensitivity analysis can be performed to check the sensitivity of the final selection (decision to minor changes in the judgement. Step by step approaches for applying AHP will be used by using AHP Calculation Software by CGI (web-based free software. It is hoped that this will encourage the application of the AHP in assessing institutional performance of similar institutions.

  18. Critical Analysis of Assessment Studies of the Animal Ethics Review Process

    Directory of Open Access Journals (Sweden)

    Orsolya Varga

    2013-09-01

    Full Text Available In many countries the approval of animal research projects depends on the decisions of Animal Ethics Committees (AEC’s, which review the projects. An animal ethics review is performed as part of the authorization process and therefore performed routinely, but comprehensive information about how well the review system works is not available. This paper reviews studies that assess the performance of animal ethics committees by using Donabedian’s structure-process-outcome model. The paper points out that it is well recognised that AECs differ in structure, in their decision-making methods, in the time they take to review proposals and that they also make inconsistent decisions. On the other hand, we know little about the quality of outcomes, and to what extent decisions have been incorporated into daily scientific activity, and we know almost nothing about how well AECs work from the animal protection point of view. In order to emphasise this viewpoint in the assessment of AECs, the paper provides an example of measures for outcome assessment. The animal suffering is considered as a potential measure for outcome assessment of the ethics review. Although this approach has limitations, outcome assessment would significantly increase our understanding of the performance of AECs.

  19. Critical Analysis of Assessment Studies of the Animal Ethics Review Process.

    Science.gov (United States)

    Varga, Orsolya

    2013-01-01

    In many countries the approval of animal research projects depends on the decisions of Animal Ethics Committees (AEC's), which review the projects. An animal ethics review is performed as part of the authorization process and therefore performed routinely, but comprehensive information about how well the review system works is not available. This paper reviews studies that assess the performance of animal ethics committees by using Donabedian's structure-process-outcome model. The paper points out that it is well recognised that AECs differ in structure, in their decision-making methods, in the time they take to review proposals and that they also make inconsistent decisions. On the other hand, we know little about the quality of outcomes, and to what extent decisions have been incorporated into daily scientific activity, and we know almost nothing about how well AECs work from the animal protection point of view. In order to emphasise this viewpoint in the assessment of AECs, the paper provides an example of measures for outcome assessment. The animal suffering is considered as a potential measure for outcome assessment of the ethics review. Although this approach has limitations, outcome assessment would significantly increase our understanding of the performance of AECs. PMID:26479540

  20. Flood disaster risk assessment of rural housings--a case study of Kouqian Town in China.

    Science.gov (United States)

    Zhang, Qi; Zhang, Jiquan; Jiang, Liupeng; Liu, Xingpeng; Tong, Zhijun

    2014-04-03

    Floods are a devastating kind of natural disaster. About half of the population in China lives in rural areas. Therefore, it is necessary to assess the flood disaster risk of rural housings. The results are valuable for guiding the rescue and relief goods layout. In this study, we take the severe flood disaster that happened at Kouqian Town in Jilin, China in 2010 as an example to build an risk assessment system for flood disaster on rural housings. Based on the theory of natural disaster risk formation and "3S" technology (remote sensing, geography information systems and global positioning systems), taking the rural housing as the bearing body, we assess the flood disaster risk from three aspects: hazard, exposure and vulnerability. The hazard presented as the flood submerging range and depth. The exposure presented as the values of the housing and the property in it. The vulnerability presented as the relationship between the losses caused by flood and flood depth. We validate the model by the field survey after the flood disaster. The risk assessment results highly coincide with the field survey losses. This model can be used to assess the risk of other flood events in this area.