Sample records for assessment study pts

  1. Mechanism of phosphoryl transfer and protein-protein interaction in the PTS system-an NMR study

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    Rajagopal, P.; Klevit, R.E. [Univ. of Washington, Seattle, WA (United States)


    HPr and Enzyme IIA{sup Glc} are two of the components of the bacterial PTS (phosphoenolpyruvate: sugar phosphotranferase system) and are involved in the phosphorylation and concomitant translocation of sugars across the membrane. These PTS protein complexes also regulate sugar transport. HPr, phosphorylated at a histidine N1 site by Enzyme I and phosphoenol pyruvate, transfers the phosphoryl group to a histidine N3 position in Enzyme IIA{sup Glc}. HPrs from Gram-positive bacteria undergo regulatory phosphorylation at Ser{sup 46}, whereby phosphorylation of the histidine residue is inhibited. Conversely, histidine phosphorylation inhibits phosphorylation at Ser{sup 46}. HPrs from Gram-negative bacteria possess a serine residue at position 46, but do not undergo regulatory phosphorylation. HPr forms an open-faced sandwich structure with a four-strand S-sheet and 2 to 3 helices lying on top of the sheet. The active-site histidine and Ser{sup 46} occur in conformationally flexible regions. P-His-HPr from the Gram-positive bacterium Bacillus subtilus has been investigated by both homonuclear and heteronuclear two-dimensional and three-dimensional NMR experiments using an in-situ enzymatic regeneration system to maintain a constant level of P-His-HPr. The results show that localized conformational changes occur in the vicinity of the active-site histidine and also near Ser{sup 46}. HPr-Enzyme IIA{sup Glc} complexes from both Bacillus subtilis and Gram-negative Escherichia coli were also studied by a variety of {sup 15}N-edited two-dimensional NMR experiments, which were performed on uniformly {sup 15}N-labeled HPr complexed to unlabeled Enzyme IIA{sup Glc}. The complex is in fast exchange with a molecular weight of about 27 kDa. The focus of our work is to assess the changes undergone by HPr (the smaller of the two components), and so all the experiments were performed with excess Enzyme IIA present in the system.

  2. Procurement Tracking System (PTS) (United States)

    Office of Personnel Management — The Procurement Tracking System (PTS) is used solely by the procurement staff of the Office of the Inspector General (OIG) at the U.S. Office of Personnel Management...


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    N F Soroka


    Full Text Available A bstract. Objective. To study the efficacy and tolerability of Remicade in RA Material and methods. 20 reliable RA pts compatible to criteria for inclusion into the study and without exclusion criteria. 18 women and 2 men aged 30-60 and older wilh disease term from 3 lo 10 years and longer. In 14 pts RA activity was of 2" J and in 6 pts оГ 3d degree. All pts long period to the beginning of the study had methotrexate in dosage of 7.5-10 mg/week and NSAID, 4 pts had metipred 4-8 mg/day. Remicade was administrated i.v. in droplet in dosage 3 ml/kg of body weight per 250.0 ml of physiological solution lor 2 hours in 0.2, 6, 8 weeks (total 9 infusions for 54 weeks. Results. Full course of Remicade therapy on the background of methotrexate was carried out in 19 pts. All pts demonstrated speedy (after I м infusion positive effect as reliable decrease of the number of inflamed joints, period of morning stiffness and ESR. Results of 54-weck course assessed as «excellent» in 9, «good» in 8 and «satisfactory» in 2 pts. In 6 cases remission was observed. Remicade tolerabilily was satisfactory. Only in 1 pts during the 7"' infusion bronchospasm and attack Quincke’s oedema she was excluded from further study. Transient hypotension was noticed in 2 pts. In 3 cases infection exacerbation developed (otitis, pneumonia which required antibiotics use.

  4. Mechanical study of the Saclay piezo tuner PTS (piezo tuning system) Care-SRF-WP8

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    Bosland, P.; Wu, B


    The present tuner is working inside Tesla test facility's cryo-modules without any piezo actuator. Thus the Lorentz force detuning in the pulsed mode of the accelerator is limiting the maximum accelerating field of cavity at about 25 MV/m. Previous studies and tests have demonstrated that the integration of piezo actuators in the tuner can lead to the compensation of the Lorentz force detuning at field higher than 35 MV/m. Our goal is now to develop and optimize a new tuner integrating piezo actuators. The mechanical studies are now finished and fabrication is in progress. This report presents the principle of this new system, its design and reviews the cavity frequency shifts during preparation process and assesses the forces applied by the cavity on the piezo actuators. (A.C.)

  5. Alflutop clinical efficacy assessment in osteoarthritis (two-years study)


    V. N. Chodyrev; N I Znaisheva; G M Lobanova; L M Ridnyak


    Objective. To assess alflutop clinical efficacy and safety during long-term course treatment of knee osteoarthritis. Methods. 51 pts with definite knee osteoarthritis of I-III stage according to Kellgren-Lawrence classification were included in an open controlled study. 20 pts received 6 intra-articular injections of alflutop 2 ml with subsequent intramuscular treatment during 3 months. Such courses were repeated 6 months apart for 2 years. 31 pts of control group received nonsteroidal anti-i...

  6. Current pulse shaping of the load current on PTS

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    Minghe Xia


    Full Text Available The typical rise time of PTS machine is ∼110 ns with about 10 MA peak current under short pulse mode when all 24 modules discharge simultaneously. By distributing the trigger times of 12 laser beams logically and adjusting the statues of the pulse output switches, longer rise-time pulse can be obtained on the PTS facility. Based on the required pulse shape, whole circuit simulations will be used to calculate the trigger times of each laser triggering gas switch and the status of the pulse output switches. The rise time of the current is determined by the time difference between the first and last trigged laser triggering gas switches. In order to trigger the laser triggering gas switch, sufficient laser power is needed to be sent into the gap of the gas switches. The gas pressure and voltage difference on the two electrodes of the gas switches also affect the triggering of the gas switches, and the voltage added on the gas switch is determined by its transition time. Traditionally the trigger time difference should be less than the transition time of the two neighboring modules. A new simulation model of PTS shows one can break this transition time limits. Series of current pulse shaping experiments have been investigated on the PTS (Primary Test Stand. As results, more than 5 MA peak current were successfully achieved on the load with a rise time of 600 ns. This study and experiments of the pulse shaping on PTS demonstrate the adaptable ability of the PTS for offering different waveform of mega ampere current pulse for different research purpose.

  7. The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS in Corynebacterium glutamicum

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    Hartmann Michelle


    Full Text Available Abstract Background The major uptake system responsible for the transport of fructose, glucose, and sucrose in Corynebacterium glutamicum ATCC 13032 is the phosphoenolpyruvate:sugar phosphotransferase system (PTS. The genes encoding PTS components, namely ptsI, ptsH, and ptsF belong to the fructose-PTS gene cluster, whereas ptsG and ptsS are located in two separate regions of the C. glutamicum genome. Due to the localization within and adjacent to the fructose-PTS gene cluster, two genes coding for DeoR-type transcriptional regulators, cg2118 and sugR, are putative candidates involved in the transcriptional regulation of the fructose-PTS cluster genes. Results Four transcripts of the extended fructose-PTS gene cluster that comprise the genes sugR-cg2116, ptsI, cg2118-fruK-ptsF, and ptsH, respectively, were characterized. In addition, it was shown that transcription of the fructose-PTS gene cluster is enhanced during growth on glucose or fructose when compared to acetate. Subsequently, the two genes sugR and cg2118 encoding for DeoR-type regulators were mutated and PTS gene transcription was found to be strongly enhanced in the presence of acetate only in the sugR deletion mutant. The SugR regulon was further characterized by microarray hybridizations using the sugR mutant and its parental strain, revealing that also the PTS genes ptsG and ptsS belong to this regulon. Binding of purified SugR repressor protein to a 21 bp sequence identified the SugR binding site as an AC-rich motif. The two experimentally identified SugR binding sites in the fructose-PTS gene cluster are located within or downstream of the mapped promoters, typical for transcriptional repressors. Effector studies using electrophoretic mobility shift assays (EMSA revealed the fructose PTS-specific metabolite fructose-1-phosphate (F-1-P as a highly efficient, negative effector of the SugR repressor, acting in the micromolar range. Beside F-1-P, other sugar-phosphates like fructose

  8. Does Evidence-Based PTS Treatment Reduce PTS Symptoms and Suicide in Iraq and Afghanistan Veterans Seeking VA Care (United States)


    AWARD NUMBER: W81XWH-15-1-0038 TITLE: Does Evidence-Based PTS Treatment Reduce PTS Symptoms and Suicide in Iraq and Afghanistan Veterans...2016 2. REPORT TYPE Annual 3. DATES COVERED 15 Apr 2015-14 Apr 2016 4. TITLE AND SUBTITLE Does Evidence-Based PTS Treatment Reduce PTS Symptoms problems among Service Members and Veterans returning from recent deployments, and despite the availability of evidence-based treatments (EBT

  9. Alflutop clinical efficacy assessment in osteoarthritis (two-years study

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    V. N. Chodyrev


    Full Text Available Objective. To assess alflutop clinical efficacy and safety during long-term course treatment of knee osteoarthritis. Methods. 51 pts with definite knee osteoarthritis of I-III stage according to Kellgren-Lawrence classification were included in an open controlled study. 20 pts received 6 intra-articular injections of alflutop 2 ml with subsequent intramuscular treatment during 3 months. Such courses were repeated 6 months apart for 2 years. 31 pts of control group received nonsteroidal anti-inflammatory drugs (NSAID only. Pain on visual analog scale, Leken functional score, changes of NSAID treatment and radiological picture were used for assessment of efficacy. Clinical examination was performed before and after every treatment course and 3 months after the last course. Results. Every alflutop treatment course provided significant stepwise decrease of pain with improvement of mobility, reduction of NSAID requirement and absence of osteoarthritis radiological progression. Doctor and pts clinical efficacy and safety assessment coincided. Conclusion. Alflutop is an effective drug for knee osteoarthritis treatment. It has anti-inflammatory and probably chondroprotective activity with good safety.

  10. Influence of combined therapy with prospidin and methotrexate on radiological progression, functional status and quality of life in pts with rheumatoid arthritis

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    O. V. Simonova


    Full Text Available Objective. To evaluate influence of combination therapy with prospidin (P and methotrexate (MTX on X-ray progression, functional status (FS and quality of life (QL in patients with rheumatoid arthritis (RA in comparison with MTX monotherapy. Material and methods. 143 RA pts (129 female and 14 male were studied. Of them, there were. Mean age was 45.5±5.l years. Average duration of the disease was 4.5 years. 20 pts had II and 123 - 111 degree of RA activity. The second X-ray stage according to Steinbroker dominated. 72 pts of group I received P+MTX combination therapy. The therapy included intravenous drip-feed of P 200-300 mg per week in 200ml of 5% glucose and MTX 10 mg per week 1M. The maintaining therapy included P 100-200 mg per week IM and MTX 10 mg per week. 71 patients of group II received MTX monotherapy 10 mg per week. X-ray progression assessment was performed according to Sharp method. FS was evaluated with the HAQ questionnaire, Lee test. QL was evaluated with SF-36 scale. Pts were examined before and after I, 2, 3, 6 and 12 months of treatment. Results. There was no increase of X-ray progression of the disease in case of P+MTX therapy as compared with MTX monotherapy. Both methods resulted in improvement of FS parameters and physical health. Combination therapy significantly improved psychological health as well.

  11. Next Generation LOCAD-PTS Cartridge Development (United States)

    Morris, H.; Nutter, D.; Weite, E.; Wells, M.; Maule, J.; Damon, M.; Monaco, L.; Steele, A.; Wainwright, N.


    Future astrobiology exploration missions will require rapid, point-of-use techniques for surface science experiments and contamination monitoring. The Lab-On-a-Chip Application Development (LOCAD) team is developing operational instruments that advance spaceflight technologies to molecular-based methods. Currently, LOCAD-Portable Test System (PTS) is quantifying levels of the bacterial molecule endotoxin onboard the Internatioal Space Station. Future research and development will focus on more sensitive molecular techniques that expand the number of compounds detected to include beta-glucan from fungal cell walls.

  12. Comparison of speed of anti-inflammatory and analgesic effect appearance of nimesulid and diclofenac sodium tablets in gout arthritis: a randomized study

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    F. M. Kudaeva


    Full Text Available To assess speed of anti-inflammatory and analgesic effect appearance of nimesulid and diclofenac sodium tablets in gout arthritis. 90 male pts with gout were included in an open clinical study. They were randomly assigned into three groups (30 pts in each. Group 1 pts received nimesulid tablets (Nise 100 mg twice a day, group 2 pts — tablets of an other nimesulid preparation and group 3 pts — diclofenac sodium 75 mg twice a day. Duration of treatment was 7 days. Nise significantly earlier provided anti-inflammatory and analgesic effect, gout arthritis, nimesulid, period till effect appearance, tolerability.

  13. Diagnostics for Z-pinch implosion experiments on PTS

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    Ren, X. D., E-mail:; Huang, X. B., E-mail:; Zhou, S. T., E-mail:; Zhang, S. Q., E-mail:; Dan, J. K., E-mail:; Li, J., E-mail:; Cai, H. C., E-mail:; Wang, K. L., E-mail:; Ouyang, K., E-mail:; Xu, Q., E-mail:; Duan, S. C., E-mail:; Chen, G. H., E-mail:; Wang, M., E-mail:; Feng, S. P., E-mail:; Yang, L. B., E-mail:; Xie, W. P., E-mail:; Deng, J. J., E-mail: [Key Lab of Pulsed Power, Institute of Fluid Physics, CAEP, P.O. Box 919-108, Mianyang, Sichuan 621999 (China)


    The preliminary experiments of wire array implosion were performed on PTS, a 10 MA z-pinch driver with a 70 ns rise time. A set of diagnostics have been developed and fielded on PTS to study pinch physics and implosion dynamics of wire array. Radiated power measurement for soft x-rays was performed by multichannel filtered x-ray diode array, and flat spectral responses x-ray diode detector. Total x-ray yield was measured by a calibrated, unfiltered nickel bolometer which was also used to obtain pinch power. Multiple time-gated pinhole cameras were used to produce spatial-resolved images of x-ray self-emission from plasmas. Two time-integrated pinhole cameras were used respectively with 20-μm Be filter and with multilayer mirrors to record images produced by >1-keV and 277±5 eV self-emission. An optical streak camera was used to produce radial implosion trajectories, and an x-ray streak camera paired with a horizontal slit was used to record a continuous time-history of emission with one-dimensional spatial resolution. A frequency-doubled Nd:YAG laser (532 nm) was used to produce four frame laser shadowgraph images with 6 ns time interval. We will briefly describe each of these diagnostics and present some typical results from them.

  14. Emerging Theoretical Models of Reading through Authentic Assessments among Preservice Teachers: Two Case Studies (United States)

    Oboler, Eileen S.; Gupta, Abha


    This two-part study examines the emerging understanding of the reading process among preservice teachers (PTs), enrolled in a teacher preparation course on diagnostic reading. The study focuses on the use of reading assessment tools to understand the process of reading, while using reading inventories for diagnostic as well as pedagogical…

  15. Design of a single-phase PTS numerical experiment for a reference Direct Numerical Simulation

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    Shams, A., E-mail:; Damiani, G.; Rosa, D.; Komen, E.M.J.


    Highlights: • A numerical experiment is designed to perform DNS for a PTS scenario. • A wide range of RANS calculations are performed to design this numerical experiment. • Mesh estimation for the targeted DNS is also performed. - Abstract: The integrity assessment of the Reactor Pressure Vessel (RPV) is considered to be an important issue for lifetime extension of nuclear reactors. A severe transient that can threaten the integrity of the RPV is the existence of a Pressurized Thermal Shock (PTS) during a Loss-of-Coolant Accident (LOCA). A PTS consists of a rapid cooling of the RPV wall under pressurized conditions that may induce the criticality of existing or postulated defects inside the vessel wall. The most severe PTS event has been identified by Emergency Core Cooling (ECC) injection during a LOCA. The traditional one-dimensional system codes fail to reliably predict the complex three-dimensional thermal mixing phenomena in the downcomer occurring during the ECC injection. Hence, CFD can bring real benefits in terms of more realistic and more predictive capabilities. However, to gain trust in the application of CFD modelling for PTS, a comprehensive validation programme is necessary. In the absence of detailed experimental data for the RPV cooling during ECC injection, high fidelity Direct Numerical Simulation (DNS) databases constitute a valid alternative and can serve as a reference. The aim of this work is to design a numerical experiment aimed to generate a high quality reference DNS database for a simplified PTS scenario. This takes into account the turbulent mixing in the downcomer and the evolution of the temperature distribution for both structures and fluid during a single-phase flow PTS scenario. In spite of simplifications, such a DNS analysis represents a very demanding application. A priori, it should be demonstrated that all the relevant turbulent scales will be fully resolved, which requires a huge computational power. A wide range of

  16. Enhancing human-like collagen accumulation by deleting the major glucose transporter ptsG in recombinant Escherichia coli BL21. (United States)

    Luo, Yan'e; Zhang, Tao; Fan, Daidi; Mu, Tingzhen; Xue, Wenjiao; Hui, Junfeng; Ma, Xiaoxuan


    Collagen has been proven to be a valuable biomedical material for many medical applications. Human-like collagen (HLC) is a novel important biomedical material with diverse medical applications. In this work, recombinant Escherichia coli BL21 3.7 ∆ptsG was constructed, the characters of ptsG mutant strain were analyzed, and real-time quantitative polymerase chain reaction (PCR) was applied to investigate the effect of ptsG gene deletion on the transcriptional level of the phosphotransferase system (PTS) genes responsible for glucose transport. The HLC production and cell growth ability were 1.33- and 1.24-fold higher than those of its parent strain in the fermentation medium, respectively, and 1.16- and 1.17-fold in the modified minimal medium individually. The acetate accumulation decreased by 42%-56% compared to its parent strain in the fermentation medium, and 70%-87% in the modified minimal medium. The results of RT-qPCR showed that the transcriptional level of crr, ptsH, ptsI, and blgF in ptsG mutant all decreased dramatically, which inferred a decrease in the glucose uptake rate, but the transcriptional level of FruB and manX increased slightly, which demonstrated the activation of fructose- and mannose-specific transport pathways in the ptsG mutant. This study demonstrates that ptsG deletion is an effective strategy to reduce acetate accumulation and increase biomass and HLC production.

  17. Construct validity of Croatian version of the Pavlovian Temperament Survey (PTS

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    Sanja Tatalović Vorkapić


    Full Text Available The aim of this study was to examine the construct validity of Pavlovian Temperament Survey (PTS by determining the relationship between three Strelau's dimensions of temperament (strength of excitation, strength of inhibition, mobility and basic dimensions of personality as were defined by Eysenck and in the five-factor model of personality. It was expected that strength of excitation and mobility would have significant positive correlations with extraversion and negative correlations with neuroticism, while strength of inhibition would show significant negative correlations with neuroticism. Within two studies (N1 = 74 female students, Mage = 22; N2 = 54 female students, Mage = 20, Croatian version of PTS, Five−Factor Nonverbal Personality Questionnaire FF−NPQ, and Eysenck's Personality Questionnaire EPQ R/A were used. The reliability coefficients for all three instruments were satisfactory, although not very high. Coefficients of correlation determined in the first study were not entirely in agreement with either theoretical expectations or empirical results of other authors, probably due to small sample size. However, the results of the second study were in accord with the expected pattern of significant correlations and that could be considered an indicator of good construct validity of PTS. Since this was a preliminary study the results provide only a general insight into the research aim, and represent a good starting point for future validation studies of the Croatian version of PTS.

  18. The methylotrophic yeast Hansenula polymorpha contains an inducible import pathway for peroxisomal matrix proteins with an N-terminal targeting signal (PTS2 proteins). (United States)

    Faber, K N; Haima, P; Gietl, C; Harder, W; Ab, G; Veenhuis, M


    Two main types of peroxisomal targeting signals have been identified that reside either at the extreme C terminus (PTS1) or the N terminus (PTS2) of the protein. In the methylotrophic yeast Hansenula polymorpha the majority of peroxisomal matrix proteins are of the PTS1 type. Thus far, for H. polymorpha only amine oxidase (AMO) has been shown to contain a PTS2 type signal. In the present study we expressed H. polymorpha AMO under control of the strong endogenous alcohol oxidase promoter. Partial import of AMO into peroxisomes was observed in cells grown in methanol/(NH4)2SO4-containing medium. However, complete import of AMO occurred if the cells were grown under conditions that induce expression of the endogenous AMO gene. Similar results were obtained when the heterologous PTS2 proteins, glyoxysomal malate dehydrogenase from watermelon and thiolase from Saccharomyces cerevisiae, were synthesized in H. polymorpha. The import of PTS1 proteins, however, was not affected by the growth conditions. These results indicate that the reduced rate of AMO import in (NH4)2SO4-grown cells is not due to competition with PTS1 proteins for the same import pathway. Apparently, AMO is imported via a separate pathway that is induced by amines and functions for PTS2 proteins in general.

  19. Fluorescent co-localization of PTS1 and PTS2 and its application in analysis of the gene function and the peroxisomal dynamic in Magnaporthe oryzae

    Institute of Scientific and Technical Information of China (English)

    Jiao-yu WANG; Fu-cheng LIN; Guo-chang SUN; Xiao-yan WU; Zhen ZHANG; Xin-fa DU; Rong-yao CHAI; Xiao-hong LIU; Xue-qin MAO; Hai-ping QIU; Yan-li WANG


    The peroxisomal matrix proteins involved in many important biological metabolism pathways in eukaryotic cells are encoded by nucleal genes, synthesized in the cytoplasm and then transported into the organelles. Targeting and import of these proteins depend on their two peroxisomal targeting signals (PTS1 and PTS2) in sequence as we have known so far. The vectors of the fluorescent fusions with PTS, i.e., green fluorescence protein (GFP)-PTSI, GFP-PTS2 and red fluorescence protein (RFP)-PTS1, were constructed and introduced into Magnaporthe oryzae Guy11 cells. Transformants containing these fusions emitted fluorescence in a punctate pattern, and the locations of the red and green fluorescence overlapped exactly in RFP-PTS1 and GFP-PTS2 co-transformed strains. These data indicated that both PTS 1 and PTS2 fusions were imported into peroxisomes. A probable higher efficiency of PTSI machinery was revealed by comparing the fluorescence backgrounds in GFP-PTS1 and GFP-PTS2 transformants. By introducing both RFP-PTS1 and GFP-PTS2 into △mgpex6 mutants, the involvement of MGPEX6 gene in both PTS1 and PTS2 pathways was proved. In addition, using these transformants, the inducement of peroxisomes and the dynamic of peroxisomal number during the pre-penetration processes were investigated as well. In summary, by the localization and co-localization of PTSI and PTS2, we provided a useful tool to evaluate the biological roles of the peroxisomes and the related genes.

  20. Two-Phase Flow Simulations for PTS Investigation by Means of Neptune_CFD Code

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    Fabio Moretti


    Full Text Available Two-dimensional axisymmetric simulations of pressurized thermal shock (PTS phenomena through Neptune_CFD module are presented aiming at two-phase models validation against experimental data. Because of PTS complexity, only some thermal-hydraulic aspects were considered. Two different flow configurations were studied, occurring when emergency core cooling (ECC water is injected in an uncovered cold leg of a pressurized water reactor (PWR—a plunging water jet entering a free surface, and a stratified steam-water flow. Some standard and new implemented models were tested: modified turbulent k-ε models with turbulence production induced by interfacial friction, models for the drag coefficient, and interfacial heat transfer models. Quite good agreement with experimental data was achieved with best performing models for both test cases, even if a further improvement in phase change modelling would be suitable for nuclear technology applications.

  1. Regulation of Streptococcus mutans PTS Bio by the transcriptional repressor NigR. (United States)

    Vujanac, M; Iyer, V S; Sengupta, M; Ajdic, D


    Streptococcus mutans is implicated in human dental caries, and the carbohydrate metabolism of this organism plays an important role in the formation of this disease. Carbohydrate transport and metabolism are essential for the survival of S. mutans in the oral cavity. It is known that a unique phosphoenolpyruvate-sugar phosphotransferase system PTS(B) (io) of S. mutans UA159 is expressed in sucrose-grown biofilms (Mol Oral Microbiol 28: 2013; 114). In this study we analyzed the transcriptional regulation of the operon (O(B) (io) ) encoding the PTS(B) (io) and showed that it was repressed by NigR, a LacI-like transcriptional regulator. Using electro-mobility shift assay, we described two operators to which NigR bound with different affinities. We also identified the transcriptional start site and showed that one of the operators overlaps with the promoter and presumably represses initiation of transcription. Mutational analyses revealed the key nucleotides in the operators required for high-affinity binding of NigR. PTS(B) (io) is expressed in S. mutans biofilms so understanding its regulation may provide improved strategies for caries treatment and prevention.

  2. The plant PTS1 receptor : similarities and differences to its human and yeast counterparts

    NARCIS (Netherlands)

    Wimmer, C; Schmid, M; Veenhuis, M; Gietl, C


    Two targeting signals, PTS1 and PTS2, mediate import of proteins into the peroxisomal matrix. We have cloned and sequenced the watermelon (Citrullus vulgaris) cDNA homologue to the PTS1 receptor gene (PEX5). Its gene product, CvPex5p, belongs to the family of tetratricopeptide repeat (TPR) containin

  3. Intraarticilar and periarticular injections of triamcinolone acetonide and a local anesthetic in knee osteoarthritis (controlled study

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    A V Glazunov


    Full Text Available Efficacy of intraarticular glucocorticoid injections in knee osteoarthritis (OA is considered to be proved. But authors do not know randomized studies comparing efficacy of intraarticular and periarticular injections of triamcinolone acetonide.Objective. To assess efficacy of intraarticular and periarticular injections of mixture of triamcinolone acetonide (TA and a local anesthetic (LA solution in comparison with injections of LA only in pts with knee OA. Material and methods. 86 pts participating in a two-center randomized double blind study ELITA (Efficacy of Local Injection Therapy of osteoArthritis were included. Each knee joint with pain value higher then 40 mm (on VAS was randomized for either intraarticular or periarticular injections of novocaine 0,5% 10 ml or its mixture with TA 20 mg. Periarticular injections were performed in regions of ligaments, muscles or tendons insertions. “Pain”, “Activity” and “Functional status” WOMAC scales were assessed at baseline, in 4, 8, and12 weeks after treatment. Results. LA injections were performed in 21 pts (group 1 – control. TA and LA mixture was injected in both knee joints of 8 pts (group 4. Periarticular injections of TA and LA mixture were performed bilaterally in 5 pts (group 6. Group 4 pts had significantly better effect than group 1 pts after 4 (“Pain” and “Functional status” scales and 8 weeks (“Functional status” scale. Group 6 pts had better results than group 1 pts after 4 (all scales, 8 (“Pain” and “Activity” scales and 12 weeks (“Activity” scale. In group 6 pts treatment was more effective than in group 4 pts after 4 (all scales, 8 and 12 weeks (“Activity” scale. Conclusion. Efficacy of TA and LA mixture intraarticular and periarticular injections in comparison with isolated LA injections was demonstrated. Effect persisted for at least 8 weeks. Periarticular injections were more effective than intraarticular.

  4. The phosphotransferase system gene ptsI in the endophytic bacterium Bacillus cereus is required for biofilm formation, colonization, and biocontrol against wheat sharp eyespot. (United States)

    Xu, Yu-Bin; Chen, Mai; Zhang, Ying; Wang, Miao; Wang, Ying; Huang, Qiu-bin; Wang, Xue; Wang, Gang


    Natural resistance of wheat plants to wheat sharp eyespot is inadequate, and new strategies for controlling the disease are required. Biological control is an alternative and attractive way of reducing the use of chemicals in agriculture. In this study, we investigated the biocontrol properties of endophytic bacterium Bacillus cereus strain 0-9, which was isolated from the root systems of healthy wheat varieties. The phosphotransferase system is a major regulator of carbohydrate metabolism in bacteria. Enzyme I is one of the protein components of this system. Specific disruption and complementation of the enzyme I-coding gene ptsI from B. cereus was achieved through homologous recombination. Disruption of ptsI in B. cereus caused a 70% reduction in biofilm formation, a 30.4% decrease in biocontrol efficacy, and a 1000-fold reduction in colonization. The growth of ΔptsI mutant strain on G-tris synthetic medium containing glucose as the exclusive carbon source was also reduced. Wild-type properties could be restored to the ΔptsI mutant strain by ptsI complementation. These results suggested that ptsI may be one of the key genes involved in biofilm formation, colonization, and biocontrol of B. cereus and that B. cereus wild-type strain 0-9 may be an ideal biocontrol agent for controlling wheat sharp eyespot.

  5. Molecular Recognition of PTS-1 Cargo Proteins by Pex5p: Implications for Protein Mistargeting in Primary Hyperoxaluria

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    Noel Mesa-Torres


    Full Text Available Peroxisomal biogenesis and function critically depends on the import of cytosolic proteins carrying a PTS1 sequence into this organelle upon interaction with the peroxin Pex5p. Recent structural studies have provided important insights into the molecular recognition of cargo proteins by Pex5p. Peroxisomal import is a key feature in the pathogenesis of primary hyperoxaluria type 1 (PH1, where alanine:glyoxylate aminotransferase (AGT undergoes mitochondrial mistargeting in about a third of patients. Here, we study the molecular recognition of PTS1 cargo proteins by Pex5p using oligopeptides and AGT variants bearing different natural PTS1 sequences, and employing an array of biophysical, computational and cell biology techniques. Changes in affinity for Pex5p (spanning over 3–4 orders of magnitude reflect different thermodynamic signatures, but overall bury similar amounts of molecular surface. Structure/energetic analyses provide information on the contribution of ancillary regions and the conformational changes induced in Pex5p and the PTS1 cargo upon complex formation. Pex5p stability in vitro is enhanced upon cargo binding according to their binding affinities. Moreover, we provide evidence that the rational modulation of the AGT: Pex5p binding affinity might be useful tools to investigate mistargeting and misfolding in PH1 by pulling the folding equilibria towards the native and peroxisomal import competent state.

  6. Substâncias tóxicas persistentes (STP no Brasil Persistent toxic substance (PTS in Brazil

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    Fernanda V. Almeida


    Full Text Available The present article presents an assessment of PTS in Brazil including polychlorinated biphenyls, polycyclic aromatic hydrocarbons, benzene hexachloride, aldrin, dieldrin, endrin, p,p,-DDT, p,p,DDE, p,p,-DDD, hexachlorocyclohexanes (alpha-HCH, beta-HCH, gamma-HCH and delta-HCH, endossulfan, heptachlor and pentachlorophenol. The data presented here are related to a survey of PTS levels in different environmental matrixes (soil, sediment, water, air, biota and human tissues (milk, blood, human hair, according to the scope of the UNEP-GEF Regionally Based Assessment of PTSs. Potential sources were evaluated considering national products and imports, since most of the literature does not allow source identification. Finally, Brazilian legislation was updated.

  7. PTS Infrasound portable array in Tunisia: Deployment and Results (United States)

    Kallel, Mohamed; Khemiri, Lotfi; Mialle, Pierrick; Le Pichon, Alexis; Vergoz, Julien


    Within the scope of a scientific collaboration between the Tunisian NDC and the PTS an infrasound portable array (I66TN) were deployed in Tunisia for 6 Months starting from 15th of May 2013 till 15th of November 2013. The 4 sites of the portable array were installed in the mountain ranges surrounding the city of Aïn Draham in northwest of Tunisia with an aperture of about 1KM. The installation was done by Dr. Pierrick Mialle, a representative from the PTS, together with a team from the Tunisian NDC. Data retrieval is performed by the Tunisian NDC team on a periodic basis. The Data recorded by I66TN and the data recorded by the IMS Infrasound Station I48TN during the same period were processed. A bulletin of the fusion of the data of the two stations was created with the support of the French NDC. In this poster, we will present the different steps of the deployment of the station I66TN and show the results of the data processing and data fusion.

  8. Assessment of quality oflife in patients with early knee osteoarthritis using SF-36

    Directory of Open Access Journals (Sweden)

    M S Svetlova


    Full Text Available Objective. To study quality of life (QL measures in pts with early knee osteoarthritis (OA with SF-36. Material and methods. 102 outpatient pts with early knee OA were included. Mean age was 48,3± 12,7 years, mean OA duration - 10,5±7,9 months. 33,3% of pts had 0, 42,6% - I, 20,5% - II stage of knee OA. According to sonographic examination of knee joints the patients were divided into two groups: group I without synovitis and group II — with synovitis of the knee joints. 50 healthy volunteers were included in control group. QL was assessed with SF-36. Results. All QL measures in early knee OA pts were lower than in control. There was significant difference of physical functioning, role physical functioning (RPF, social functioning (SF and role emotional functioning (REF (p<0,05. Pts of group II had significantly lower RPF and REF than group I pts (p<0,05. Conclusion. QL of pts with knee OA decrease at early stage of the disease what requires administration of proper therapy as soon as possible after verification of the diagnosis.

  9. PAPR Reduction in OFDM Using Partial Transmit Sequence (PTS

    Directory of Open Access Journals (Sweden)



    Full Text Available In recent years, OFDM has gained a lot of interest in diverse-digital communication applications. This has been due to its favorable properties like high spectral efficiency and robustness to channel fading. Some of the major drawbacks in OFDM are its high peak-to-average-power ratio(PAPR of the transmitted signals and the synchronization of signals. OFDM consist of large number of independent subcarriers, as a result of which the amplitude of such a signal can have high peak values. Coding, phase rotation and clipping are among many PAPR reduction schemes that have been proposed to overcome this problem. Significant reduction in PAPR has been achieved using Partial Transmit Sequence(PTS which comes under Signal scrambling techniques.

  10. A PTS EII mutant library in Group A Streptococcus identifies a promiscuous man-family PTS transporter influencing SLS-mediated hemolysis. (United States)

    Sundar, Ganesh S; Islam, Emrul; Gera, Kanika; Le Breton, Yoann; McIver, Kevin S


    The Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive human pathogen that must adapt to unique host environments in order to survive. Links between sugar metabolism and virulence have been demonstrated in GAS, where mutants in the phosphoenolpyruvate-dependent phosphotransferase system (PTS) exhibited Streptolysin S (SLS)-mediated hemolysis during exponential growth. This early onset hemolysis correlated with an increased lesion size and severity in a murine soft tissue infection model when compared with parental M1T1 MGAS5005. To identify the PTS components responsible for this phenotype, we insertionally inactivated the 14 annotated PTS EIIC-encoding genes in the GAS MGAS5005 genome and subjected this library to metabolic and hemolysis assays to functionally characterize each EIIC. It was found that a few EIIs had a very limited influence on PTS sugar metabolism, whereas others were fairly promiscuous. The mannose-specific EII locus, encoded by manLMN, was expressed as a mannose-inducible operon that exhibited the most influence on PTS sugar metabolism, including mannose. Importantly, components of the mannose-specific EII also acted to prevent the early onset of SLS-mediated hemolysis. Interestingly, these roles were not identical in two different M1T1 GAS strains, highlighting the possible versatility of the PTS to adapt to strain-specific needs.

  11. The relevance of the non-canonical PTS1 of peroxisomal catalase

    NARCIS (Netherlands)

    Williams, Chris; Aksam, Eda Bener; Gunkel, Katja; Veenhuis, Marten; van der Klei, Ida J.


    Catalase is sorted to peroxisomes via a C-terminal peroxisomal targeting signal 1 (PTS1), which binds to the receptor protein Pex5. Analysis of the C-terminal sequences of peroxisomal catalases from various species indicated that catalase never contains the typical C-terminal PTS1 tripeptide-SKL, bu

  12. Quality of life characteristics in assessment of diclofenac and Nise® efficacy in patients with gonarthritis

    Directory of Open Access Journals (Sweden)

    L V Sizova


    Full Text Available Objective. To study efficacy and safety of diclofenac and Nise® application in pts with gonarthritis. Material and methods. 60 pts with gonarthritis were included (mean age 53,4±9,5 years, mean disease duration 7,4±6,8 years. Quality of life was assessed with 4 questionnaires: Modified Stanford Health Assessment Questionnaire (MHAQ, SF-36, Nottingham Health Profile (NHP, Knee injury and Osteoarthritis Outcome Score (KOOS. 30 pts of group I received diclofenac 75 mg/day, 30 pis of group 11 were treated with Nise® 200 mg/day for 10 days. Multi-vitamins "Decamevitum" and injections of Xantinoli nicotinatis were used as additional treatment. Results. Diclofenac and Nise® showed good analgesic and anti-inflammatory effect. Both provided quality of life improvement in pts with gonarthrosis. Nise® was better tolerated.

  13. PredPlantPTS1: A Web Server for the Prediction of Plant Peroxisomal Proteins. (United States)

    Reumann, Sigrun; Buchwald, Daniela; Lingner, Thomas


    Prediction of subcellular protein localization is essential to correctly assign unknown proteins to cell organelle-specific protein networks and to ultimately determine protein function. For metazoa, several computational approaches have been developed in the past decade to predict peroxisomal proteins carrying the peroxisome targeting signal type 1 (PTS1). However, plant-specific PTS1 protein prediction methods have been lacking up to now, and pre-existing methods generally were incapable of correctly predicting low-abundance plant proteins possessing non-canonical PTS1 patterns. Recently, we presented a machine learning approach that is able to predict PTS1 proteins for higher plants (spermatophytes) with high accuracy and which can correctly identify unknown targeting patterns, i.e., novel PTS1 tripeptides and tripeptide residues. Here we describe the first plant-specific web server PredPlantPTS1 for the prediction of plant PTS1 proteins using the above-mentioned underlying models. The server allows the submission of protein sequences from diverse spermatophytes and also performs well for mosses and algae. The easy-to-use web interface provides detailed output in terms of (i) the peroxisomal targeting probability of the given sequence, (ii) information whether a particular non-canonical PTS1 tripeptide has already been experimentally verified, and (iii) the prediction scores for the single C-terminal 14 amino acid residues. The latter allows identification of predicted residues that inhibit peroxisome targeting and which can be optimized using site-directed mutagenesis to raise the peroxisome targeting efficiency. The prediction server will be instrumental in identifying low-abundance and stress-inducible peroxisomal proteins and defining the entire peroxisomal proteome of Arabidopsis and agronomically important crop plants. PredPlantPTS1 is freely accessible at

  14. PredPlantPTS1: a web server for the prediction of plant peroxisomal proteins

    Directory of Open Access Journals (Sweden)

    Sigrun eReumann


    Full Text Available Prediction of subcellular protein localization is essential to correctly assign unknown proteins to cell organelle-specific protein networks and to ultimately determine protein function. For metazoa, several computational approaches have been developed in the past decade to predict peroxisomal proteins carrying the peroxisome targeting signal type 1 (PTS1. However, plant-specific PTS1 protein prediction methods have been lacking up to now, and pre-existing methods generally were incapable of correctly predicting low-abundance plant proteins possessing non-canonical PTS1 patterns. Recently, we presented a machine learning approach that is able to predict PTS1 proteins for higher plants (spermatophytes with high accuracy and which can correctly identify unknown targeting patterns, i.e. novel PTS1 tripeptides and tripeptide residues. Here we describe the first plant-specific web server PredPlantPTS1 for the prediction of plant PTS1 proteins using the above-mentioned underlying models. The server allows the submission of protein sequences from diverse spermatophytes and also performs well for mosses and algae. The easy-to-use web interface provides detailed output in terms of (i the peroxisomal targeting probability of the given sequence, (ii information whether a particular non-canonical PTS1 tripeptide has already been experimentally verified, and (iii the prediction scores for the single C-terminal 14 amino acid residues. The latter allows identification of predicted residues that inhibit peroxisome targeting and which can be optimized using site-directed mutagenesis to raise the peroxisome targeting efficiency. The prediction server will be instrumental in identifying low-abundance and stress-inducible peroxisomal proteins and defining the entire peroxisomal proteome of Arabidopsis and agronomically important crop plants. PredPlantPTS1 is freely accessible at

  15. The Rhizobium etli rpoN Locus: DNA Sequence Analysis and Phenotypical Characterization of rpoN, ptsN, and ptsA Mutants


    Michiels, Jan; Van Soom, Tom; D’hooghe, Inge; Dombrecht, Bruno; Benhassine, Traki; Wilde, Petra; Vanderleyden, Jos


    The rpoN region of Rhizobium etli was isolated by using the Bradyrhizobium japonicum rpoN1 gene as a probe. Nucleotide sequence analysis of a 5,600-bp DNA fragment of this region revealed the presence of four complete open reading frames (ORFs), ORF258, rpoN, ORF191, and ptsN, coding for proteins of 258, 520, 191, and 154 amino acids, respectively. The gene product of ORF258 is homologous to members of the ATP-binding cassette-type permeases. ORF191 and ptsN are homologous to conserved ORFs f...

  16. A Low-Complexity PTS Based on Greedy and Genetic Algorithm for OFDM Systems

    Institute of Scientific and Technical Information of China (English)

    LUO Renze; ZHANG Chengsen; NIU Na; LI Rui


    Partial transmit sequence (PTS) is one of eff ective technique to reduce high Peak-to-average power ratio (PAPR) in Orthogonal frequency division multiplex-ing (OFDM) system. However, the complexity of Original PTS (O-PTS) increases exponentially with the number of sub-blocks. To reduce the computational complexity while still off ering a lower PAPR, a new PTS method is pro-posed to search for suboptimal rotating vectors in this pa-per. In the proposed method, the candidate rotation vec-tors are generated based on greedy and genetic algorithm. We also combine the proposed method and the superim-posed training sequence method to get a further PAPR reduction. The theory and simulations results show that the proposed method can achieve better PAPR reduction and significantly reduce the computational complexity.

  17. [Repression of the enzyme inducible syntheses in Escherichia coli K12 mutant with a deleted ptsH gene]. (United States)

    Gershanovich, V N; Il'ina, T S; Rusina, O Iu; Iurovitskaia, N V; Bol'shakova, T N


    The genome of lambda phage with thermosensitive repressor was integrated into the pts region of the E. coli chromosome. Such a lysogenic culture behaves as a pts mutant at 30 degrees. Heating of cells of this strain leads to the induction of lambda prophage and formation of deletions in the pts region. A mutant with a deletion covering ptsH gene was isolated after prophage induction. The deletion nature of pts mutation was confirmed in genetic and biochemical experiments. It was shown that the deletion is small and does not involve ptsI and lig genes. The isolated deltaptsH mutant possesses all characteristics of pts mutants: pleiotropic impairment of transport and utilization of a number of carbohydrates, repression of the enzyme inducible synthesis and resistance to catabolite repression with glucose. These data (together with earlier ones) allow us to conclude that the phosphorylated form of HPr is involved (in direct of indirect manner/ in activation of DNA transcription.

  18. First expirience of adalimumab administration in Russia: preliminary results of an open 24 week study

    Directory of Open Access Journals (Sweden)

    E L Luchichina


    Full Text Available Introduction. Adalimumab (Humira is a monoclonal anti-TNFa antibody fully identical to human antibodies, a member of group of TNFa blockers which are now the main biological drugs for the treatment of rheumatoid arthritis (RA. Till recently adalimumab was little known in Russia. Material and methods. 24 pts (2 male and 22 female were included in an open 24-week clinical study of adalimumab in active RA. Mean duration of the disease was 6,4 years. 5 pts had early RA. In all pts DAS28 was higher than 5,1. All pts earlier received main traditional DMARDs (methotrexate, leflunomide, sulfasalazine and steroids without significant improvement. All pts were treated on an outpatient basis. Adalimumab 40 mg was injected subcutaneously with 2 weeks intervals during 24 weeks. Results. 22 from 24 pts (91,7% completed full course of treatment with adalimumab. All outcome measures (pt self assessment on VAS, DAS28,HAQ, CRP showed fast and sustained improvement. Good effect according to EULAR criteria was achieved in 8 (33,4%, moderate — in 14 (58,3% pts and 2 pts (8,3% did not respond to the treatment. Effect did not depend on age, previous treatment, comorbid diseases and disease duration. During follow up period serious adverse events and tuberculosis did not appear in this group of pts. Conclusion. Adalimumab is a highly effective biological drug from the group of TNFa blockers which is particularly useful for the treatment of RA resistant to conventional therapy on an outpatient basis.

  19. Functional characterization of the incomplete phosphotransferase system (PTS of the intracellular pathogen Brucella melitensis.

    Directory of Open Access Journals (Sweden)

    Marie Dozot

    Full Text Available BACKGROUND: In many bacteria, the phosphotransferase system (PTS is a key player in the regulation of the assimilation of alternative carbon sources notably through catabolic repression. The intracellular pathogens Brucella spp. possess four PTS proteins (EINtr, NPr, EIIANtr and an EIIA of the mannose family but no PTS permease suggesting that this PTS might serve only regulatory functions. METHODOLOGY/PRINCIPAL FINDINGS: In vitro biochemical analyses and in vivo detection of two forms of EIIANtr (phosphorylated or not established that the four PTS proteins of Brucella melitensis form a functional phosphorelay. Moreover, in vitro the protein kinase HprK/P phosphorylates NPr on a conserved serine residue, providing an additional level of regulation to the B. melitensis PTS. This kinase activity was inhibited by inorganic phosphate and stimulated by fructose-1,6 bisphosphate. The genes encoding HprK/P, an EIIAMan-like protein and NPr are clustered in a locus conserved among α-proteobacteria and also contain the genes for the crucial two-component system BvrR-BvrS. RT-PCR revealed a transcriptional link between these genes suggesting an interaction between PTS and BvrR-BvrS. Mutations leading to the inactivation of EINtr or NPr significantly lowered the synthesis of VirB proteins, which form a type IV secretion system. These two mutants also exhibit a small colony phenotype on solid media. Finally, interaction partners of PTS proteins were identified using a yeast two hybrid screen against the whole B. melitensis ORFeome. Both NPr and HprK/P were shown to interact with an inorganic pyrophosphatase and the EIIAMan-like protein with the E1 component (SucA of 2-oxoglutarate dehydrogenase. CONCLUSIONS/SIGNIFICANCE: The B. melitensis can transfer the phosphoryl group from PEP to the EIIAs and a link between the PTS and the virulence of this organism could be established. Based on the protein interaction data a preliminary model is proposed in which

  20. Spine inflammatory changes in patients with ankylosing spondylitis assessed by magnetic resonance image

    Directory of Open Access Journals (Sweden)

    A G Bochkova


    Full Text Available Objective. To develop the optimal mode of spine evaluation with magnetic resonance image (MRl in pts with ankylosing spondylitis (AS and to study relationship between MR! signs of spinal inflammatory lesions (IL, spondylitis duration and clinical features of AS activity. Material and methods. MRl was performed in 36 pts (22 male, 14 female fulfilling the modified NY criteria of AS. Median age of pis was 26 years (range 19 - 55, Median AS duration - 8 years (range 1,8 - 24. 34 (97% pts were HLA-B27 positive. 21 (64% pts had high AS activity - median BASDAI 40 (range 10 - 77. 92% of pts had inflammatory spine pain (VAS>20 mm and 61% of pts had night pain. Median inflammatory pain duration had been defined separately for every part of the spine assessed by MRl. Median duration of axial pain was 36 months (range: 1-240. MR-scanning (Magnetom Symphony, Siemens, 1.5 T was performed inTl, T2 and T2-FS (fat signal suppression modes. IL scoring was done only in 29 pts evaluated in both sagittal and axial planes. We used two scoring methods: 1 individual IL score of the each spine element (vertebral bodies, processes, arches, zygapophyseai, costovertebral and costotransverse joints, ligaments, and 2 separate IL scoring in the vertebral bodies and posterior spinal elements in order "yes/no”. Results. 50 MRl images of different parts of the spine (8 cervical, 30 thoracic and 12 lumbar have been obtained in 36 pts. Spine IL were found in 35 pts. 26% of all IL were revealed in axial planes. 3 pts with short AS duration had IL only on axial slices (zygapophyseai lumbar joints, costotransverse joints, processes. IL were revealed more often in thoracic (average score: 7.1, than in lumbar (3.7 and cervical (2.1 spine. In most (26 from 29 pts, 90% pts IL were found in painful parts of spine. There was no IL score difference between pts(n=12 with low (BASDAI <40 and high (BASDAI>40; n=17 AS activity. Me and range were 4 (1.8-10.3 and 6 (4-16, respectively; p=0

  1. Two-phase CFD PTS validation in an extended range of thermohydraulics conditions covered by the COSI experiment

    Energy Technology Data Exchange (ETDEWEB)

    Coste, P., E-mail: [CEA, DEN/DANS/DM2S/SMTF/LMSF, 17 rue des Martyrs, 38054 Grenoble (France); Ortolan, A. [CEA, DEN/DANS/DM2S/SMTF/LMSF, 17 rue des Martyrs, 38054 Grenoble (France); ENSICA Engineering School, Toulouse (France)


    Highlights: • Models for large interfaces in two-phase CFD were developed for PTS. • The COSI experiment is used for NEPTUNE{sub C}FD integral validation. • COSI is a PWR cold leg scaled 1/100 for volume. • Fifty runs are calculated, covering a large range of flow configurations. • The CFD predicting capability is analysed using global and local measurements. - Abstract: In the context of the Pressurized Water Reactors (PWR) life duration safety studies, some models were developed to address the Pressurized Thermal Shock (PTS) from the two-phase CFD angle, dealing with interfaces much larger than cells size and with direct contact condensation. Such models were implemented in NEPTUNE{sub C}FD, a 3D transient Eulerian two-fluid model. The COSI experiment is used for its integral validation. It represents a cold leg scaled 1/100 for volume and power from a 900 MW PWR under a large range of LOCA PTS conditions. In this study, the CFD is evaluated in the whole range of parameters and flow configurations covered by the experiment. In a first step, a single choice of mesh and CFD models parameters is fixed and justified. In a second step, fifty runs are calculated. The CFD predicting capability is analysed, comparing the liquid temperature and the total condensation rate with the experiment, discussing their dependency on the inlet cold liquid rate, on the liquid level in the cold leg and on the difference between co-current and counter-current runs. It is shown that NEPTUNE{sub C}FD 1.0.8 calculates with a fair agreement a large range of flow configurations related to ECCS injection and steam condensation.

  2. LOCAD-PTS: Operation of a New System for Microbial Monitoring Aboard the International Space Station (ISS) (United States)

    Maule, J.; Wainwright, N.; Steele, A.; Gunter, D.; Flores, G.; Effinger, M.; Danibm N,; Wells, M.; Williams, S.; Morris, H.; Monaco, L.


    Microorganisms within the space stations Salyut, Mir and the International Space Station (ISS), have traditionally been monitored with culture-based techniques. These techniques involve growing environmental samples (cabin water, air or surfaces) on agar-type media for several days, followed by visualization of resulting colonies; and return of samples to Earth for ground-based analysis. This approach has provided a wealth of useful data and enhanced our understanding of the microbial ecology within space stations. However, the approach is also limited by the following: i) More than 95% microorganisms in the environment cannot grow on conventional growth media; ii) Significant time lags occur between onboard sampling and colony visualization (3-5 days) and ground-based analysis (as long as several months); iii) Colonies are often difficult to visualize due to condensation within contact slide media plates; and iv) Techniques involve growth of potentially harmful microorganisms, which must then be disposed of safely. This report describes the operation of a new culture-independent technique onboard the ISS for rapid analysis (within minutes) of endotoxin and -1, 3-glucan, found in the cell walls of gram-negative bacteria and fungi, respectively. This technique involves analysis of environmental samples with the Limulus Amebocyte Lysate (LAL) assay in a handheld device. This handheld device and sampling system is known as the Lab-On-a-Chip Application Development Portable Test System (LOCAD-PTS). A poster will be presented that describes a comparative study between LOCAD-PTS analysis and existing culture-based methods onboard the ISS; together with an exploratory survey of surface endotoxin throughout the ISS. It is concluded that while a general correlation between LOCAD-PTS and traditional culture-based methods should not necessarily be expected, a combinatorial approach can be adopted where both sets of data are used together to generate a more complete story of

  3. The Performance Analysis of PAPR Reduction using a novel PTS technique in OFDM-MIMO System

    Directory of Open Access Journals (Sweden)

    Kashish Sareen


    Full Text Available Orthogonal Frequency Division Multiplexing (OFDM is an new multiplexing technique for 4G and 4.5G generation wireless communication. MIMO-OFDM is latest multiplexing technique which is resposible for high performance 4G broadband wireless communications. But there is one main disadvantage of MIMO-OFDM is the high peak-to-average power ratio (PAPR of the transmitter’s output signal on different antennas. In this paper, we present a new noble (PTS Partial transmit sequence technique to reduce PAPR problem in OFDM-MIMO system. This new PTS technique gives us better PAPR Reduction gain in OFDM-MIMO as compared with original and another PTS Techniques.

  4. Optimization of PTS2-EGFP Expression in CHO and Vero Cells

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    Roozbeh Ghodratnama


    Full Text Available Objective: Reporter gene transfer to mammalian cells receives a great deal of attention due to its importance for molecular biology, embryology and developmental biology studies. Among DNA transfer technologies to eukaryotic cells, lipofection is known as the most widely used because of its easy handling procedure, low cell mortality and the natural pathway it undertakes.Materials and Methods: In this study we have examined the transfectability of two cell types: CHO and Vero cells via Lipofection in four different treatments, with combination of exposure duration, 3 and 6 hrs, and different plasmid DNA concentration, 0.5 and 1μgs. A fusion protein expression vector, pUcD2. PTS2-EGFP was used to direct the EGFP protein to peroxisomes after expression of related cDNA. An SPSS analysis was preformed after counting the positive cells.Results: optimum gene expression was found when using 1 μg DNA treated for three hrs for CHO cells, and 1 μg DNA treated for six hrs for Vero cells.Conclusion: The result suggests that CHO lipofection efficiency is significantly increased by both the DNA concentration and exposure time increment; however, an increase in exposure time has less significant effect on low DNA concentration conditions. The same results have been observed for Vero cells. Optimum expression was obtained with highest DNA concentration.

  5. PAPR Reduction Using BPSO/PTS and STBC in MIMO OFDM System

    Directory of Open Access Journals (Sweden)

    Karima El Mouhib


    Full Text Available Problem statement: The Multiple Input Multiple Output (MIMO Orthogonal Frequency Division Multiplexing (OFDM system has been receiving a great attention, as one of solutions for achieving high speed, efficient and high-quality service for the wireless communications. However, the transmitted signal still has high PAPR because of OFDM characteristics. Many methods have been proposed to solve this problem, but the most of them decrease high Peak-to-Average Power Ratio (PAPR as well as the data rate. Approach: This proposal described a new suboptimal technique for reduction of the PAPR by combining two suitable methods for MIMO OFDM systems. The first method was based on Boolean Particle Swarm intelligence Optimization (BPSO applied to Partial transmit Sequence (PTS and the second was the Space Time Bloc Coding (STBC. Result: Apply only the PTS technique and independently on each transmitted antenna, was effective to reduce PAPR, but it requires high computation complexity. Therefore, the BPSO/PTS technique provided better performance and it was been promoted as an uncomplicated way for PAPR reduction. Thanks of the BPSO/PTS algorithm; the transmitted sequence was selected with minimizing the maximum PAPR over all transmission antennas. The simulations and the BER performance demonstrated that more inertia weight and phase weighting factor obtained better PAPR reduction performance without bringing much higher complexity. Conclusion: Results show that the added BPSO/PTS method to orthogonal space time bloc coding minimizes computational complexity cost as well as the PAPR and gives best optimal PTS performance in comparison with the conventional methods.

  6. Optimizing of the XRD 3000PTS for diffractometry and reflectometry on thin films


    Kehr, Mirko


    Thin films become more and more important in science and industry. The main objective of this work was the expanding of the measurement capabilities of the XRD 3000PTS to the field of thin films. The success of the changes was documented by maesurements on TiC thin films. Dünne Schichten gewinnen in Forschung und Industrie zunehmend an Bedeutung. Ziel der Arbeit war es deshalb, den Einsatzbereich des vorhandenen Diffraktometers XRD 3000PTS auf Untersuchungen an dünnen Schichten zu erweiter...

  7. Service framework for Internet of People, Things and Services (IoPTS)

    DEFF Research Database (Denmark)

    Shinde, Gitanjali; Olesen, Henning


    the literature work,a detaileddiscussionon the requirements, functionalities and need of the user-centric service frameworkthat is needed to realize IoPTS is presented in this work.We propose amodified Bluetooth Low Energy (BLE) beacon to advertise the services present at a particular location in the view...

  8. A comparative study of self-perceived public health competencies: practice teachers and qualifying SCPHNs. (United States)

    Poulton, Brenda; Lyons, Agatha; O'Callaghan, Anne


    There is evidence to suggest that population-focused public health nursing is more rhetoric than reality. This quantitative study compares the self-perceived public health competence of qualifying student specialist community public health nurses (SCPHNs) (n = 35) with those of the practice teachers (PTs) facilitating their practice learning (n = 31). Findings suggest that PTs felt more competent than qualifying students on leadership and management for public health, working with communities, and communication skills. However, the qualifying students self-rated higher than the PTs on principles and practice of public health, suggesting that the PTs in this study felt less competent than their qualifying students in key public health skills, such as epidemiology, population health needs assessment, research and evidence-based decision-making. It is recommended that the triennial review of PTs should address not only educational skills but knowledge and skills in contemporary public health practice, a continuing professional development framework for SCPHNs should be developed and funded, providers should assist PTs in keeping up with contemporary public health, and the role of the PT should be recognised and given appropriate support and remuneration.

  9. Enterococcus faecalis uses a PTS permease and a host colonization-related ABC transporter for maltodextrin uptake. (United States)

    Sauvageot, Nicolas; Mokhtari, Abdelhamid; Joyet, Philippe; Budin-Verneuil, Aurélie; Blancato, Víctor S; Repizo, Guillermo D; Henry, Céline; Pikis, Andreas; Thompson, John; Magni, Christian; Hartke, Axel; Deutscher, Josef


    Maltodextrin is a mixture of maltooligosaccharides, which are produced by the degradation of starch or glycogen. They are mostly composed of α-1,4- and some α-1,6- linked glucose residues. Genes presumed to code for the Enterococcus faecalis maltodextrin transporter were induced during enterococcal infection. We therefore carried out a detailed study of maltodextrin transport in this organism. Depending on their length (3 to 7 glucose residues), E. faecalis takes up maltodextrins either via MalT, a maltose-specific permease of the phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS), or the ATP binding cassette (ABC) transporter MdxEFG/MsmX. Maltotriose, the smallest maltodextrin, is primarily transported by the PTS permease. A malT mutant therefore exhibits significantly reduced growth on maltose and maltotriose. The residual uptake of the trisaccharide is catalyzed by the ABC transporter, because a malT/mdxF double mutant no longer grows on maltotriose. The trisaccharide arrives as maltotriose-6″-P in the cell. MapP, which dephosphorylates maltose-6' -P, also releases Pi from maltotriose-6″-P. Maltotetraose and longer maltodextrins are mainly (or exclusively) taken up via the ABC transporter, because inactivation of the membrane protein MdxF prevents growth on maltotetraose and longer maltodextrins up to at least maltoheptaose. E. faecalis also utilizes panose and isopanose and we show for the first time that in contrast to maltotriose its two isomers are primarily transported via the ABC transporter. We confirm that maltodextrin utilization via MdxEFG/MsmX affects the colonization capacity of E. faecalis, because inactivation of mdxF significantly reduced enterococcal colonization and/or survival in kidneys and liver of mice after intraperitoneal infection.IMPORTANCE Infections by enterococci, major health-care associated pathogens, are difficult to treat due to their increasing resistance to clinically relevant antibiotics and new

  10. Evaluation of a portable test system for assessing endotoxin activity in raw milk. (United States)

    Suzuki, Yohko; Suzuki, Kazuyuki; Shimamori, Toshio; Tsuchiya, Masakazu; Niehaus, Andrew; Lakritz, Jeffrey


    The aim of the present study was to compare endotoxin activities detected in raw milk samples obtained from cattle by a commercially available portable test system (PTS) and traditional microplate limulus amebocyte lysate (LAL)-based assay, which determined activities using a kinetic turbidimetric (KT) assay. Raw milk samples were obtained from 53 and 12 dairy cattle without and with clinical mastitis, respectively. Comparison between the KT and PTS was performed by the Friedman test. The Pearson product moment correlation coefficients were calculated to evaluate associations between any two continuous variables. Linear regression model analysis was also performed to obtain the equation describing the relationship between PTS and KT assay. The endotoxin activities detected in 200- or 400-fold diluted milk samples were similar between PTS and KT assay, whereas a significant difference was observed in 100-fold diluted milk (PPTS correlated with those using KT assay. The median milk endotoxin activities in Gram-positive and Gram-negative clinical mastitis cows were 0.655 and 11,523.5 EU/ml, respectively. The results of the present study suggest that PTS as a simple and easy test to assess endotoxin activity in raw milk is efficient, simple and reproducible.

  11. Transesophageal echocardiography in the assessment of coronary arteries; Echokardiografia przezprzelykowa w ocenie proksymalnych odcinkow naczyn wiencowych

    Energy Technology Data Exchange (ETDEWEB)

    Adamek-Kosmider, A.; Kasprzak, J.; Kosmider, M.; Krzeminska-Pakula, M. [Akademia Medyczna, Lodz (Poland)


    The study was undertaken to assess the usefulness of TEE for evaluation of morphology and flow in coronary arteries. TEE (2D, spectral and color Doppler imaging) and coronary angiography were performed in 75 patients - 41 with valvular heart disease and 34 with ischemic heart disease. Proximal coronary artery stenosis was detected by coronarography in 11 pts (9-left main coronary artery, 2-right coronary artery). TEE visualization of proximal coronary arteries was possible in all pts. Echocardiographic features of artery stenosis were: the narrowing of the vessel in 2D image (9 pts), high flow velocity spectral Doppler (4 pts, mean 135 cm/s vs 55 cm/s in normal arteries) and mosaic, turbulent flow in color Doppler (10 pts). Sensitivity and specificity of TEE for coronary artery stenosis detection was respectively 81%/98% for 2D imaging and 90%/100% for color Doppler. TEE is a new, noninvasive and safe method for the evaluation of proximal coronary arteries. Detection of LMCA stenosis prior to atheterization may enhance the safety of coronary angiography. (author) 21 refs, 8 figs

  12. The methylotrophic yeast Hansenula polymorpha contains an inducible import pathway for peroxisomal matrix proteins with an N-terminal targeting signal (PTS2 proteins)

    NARCIS (Netherlands)

    Faber, Klaas Nico; Haima, Pieter; Gietl, Christine; Harder, Willem; Ab, Geert; Veenhuis, Marten


    Two main types of peroxisomal targeting signals have been identified that reside either at the extreme C terminus (PTS1) or the N terminus (PTS2) of the protein. In the methylotrophic yeast Hansenula polymorpha the majority of peroxisomal matrix proteins are of the PTS1 type. Thus far, for H. polymo

  13. Synbiotic impact of tagatose on viability of Lactobacillus rhamnosus strain GG mediated by the phosphotransferase system (PTS). (United States)

    Koh, Ji Hoon; Choi, Seung Hye; Park, Seung Won; Choi, Nag-Jin; Kim, Younghoon; Kim, Sae Hun


    Synbiotics, the combination of prebiotics and probiotics, has been shown to produce synergistic effects that promote gastrointestinal well-being of host. Tagatose is a low calorie food ingredient with putative health-promoting benefits. Herein, we investigated its synbiotic impact on the viability of Lactobacillus casei 01 and Lactobacillus rhamnosus strain GG and the potential mechanism involved. Tagatose, as a synbiotic substrate, enhanced the growth of L. casei 01 and L. rhamnosus strain GG compared to other prebiotics. Other gut-indigenous such as Clostridium spp. readily utilized fructooligosaccharide (FOS), the most widely used functional prebiotics, but not tagatose. Additionally, tagatose enhanced probiotic functions of L. casei 01 and L. rhamnosus strain GG by reinforcing their attachment on HT-29 intestine epithelial cells and enhancing their cholesterol-lowering activities. Whole transcriptome study and quantitative real-time polymerase chain reaction (qRT-PCR) test showed that the presence of tagatose in L. rhamnosus strain GG caused induction of a large number of genes associated with carbohydrate metabolism including the phosphotransferase system (PTS). Collectively, these results indicate the tagatose enhanced the growth of L. casei 01 and L. rhamnosus strain GG and their probiotic activities by activating tagatose-associated PTS networks. Importantly, this study highlights the potential application of tagatose and L. casei 01 and/or L. rhamnosus strain GG as a synbiotic partner in functional dairy foods (i.e. yogurt and cheese) and therapeutic dietary supplements.

  14. Effect of the dilution factor on {sup 18}FDG and Na{sup 18}F samples for bacterial endotoxin test using PTS (portable test system)

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, Marina B.; Costa, Flavia M.; Ferreira, Soraya Z., E-mail: mbs@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Unidade de Pesquisa e Producao de Radiofarmacos


    {sup 18}FDG and Na{sup 18}F are radiopharmaceuticals produced as sterile solutions suitable for intravenous administration, which must contain no more than 175 EV/V. The most commonly used approach to detect endotoxins is the gelclot technique that requires 60 minutes for results. For radiopharmaceuticals containing short-life radionuclides, such as {sup 18}F, there is an increasing interest for faster quality control methods. FDA licensed the Endosafe, PTS, a kinetic chromogenic endotoxin detection system that takes about 15 minutes for results. As other techniques, PTS test is susceptible to interferences which can be solved by product dilution. The aim of this study was to establish the best dilution of {sup 18}FDG and Na{sup 18}F for PTS analysis. Two different dilution factors for {sup 18}FDG and 1:10 for Na{sup 18}F were essayed: 1:10 and 1:100. {sup 18}FDG and Na{sup 18} solutions were prepared by the addition of LAL reagent water. Considering the assay acceptance criteria, the best dilution factor was 1:100 for {sup 18}FDG and 1:10 for Na{sup 18}F. The recovery of the product positive control was 98-12% for {sup 18}FDG 1:100 and 104-120% for Na{sup 18}F 1:10, which were, in both cases, within the specification (50-200%) and very close to 100%. Results obtained with these dilution studies were important to establish the most appropriate and non-interfering dilution factor for {sup 18}FDG and Na{sup 18}F routine endotoxin test. (author)

  15. SIMBOSPROST: Prevalence of metabolic syndrome and osteoporosis in prostate cancer patients treated with radiotherapy and androgen deprivation therapy: A multicentre, cross-sectional study (United States)

    Samper Ots, Pilar Ma; Muñoz García, Julia Luisa; Ríos Kavadoy, Yesika; Couselo Paniagua, Ma Luz; Villafranca Iturre, Elena; Rodríguez Liñán, Milagrosa; Pérez Casas, Ana María; Soria, Rodrigo Muelas; Martínez, Blanca Ludeña; Torrecilla, José López; Giner, Manuel Casaña; Laborda, Almudena Zapatero; García-Salazar, Ma Magdalena Márquez


    Aim To assess the prevalence of metabolic syndrome (MetS) and osteoporosis in patients with prostate cancer (PCa) treated with radical radiotherapy (RT) with or without androgen deprivation therapy (ADT). Background Worldwide, the prevalence of MetS is estimated to range from 20% to 25% of the adult population. However, prevalence rates are much higher in PCa patients (pts) who undergo ADT. Materials and methods Multicentre cross-sectional study of 270 pts in Spain with PCa. Patients were divided into 3 groups based on the duration of ADT (6, 12–18, ≥24 months) and compared to a control group without ADT. MetS was defined according to NCEP ATP III criteria. Osteoporosis was assessed by DEXA. Results A total of 270 pts, treated from November 2011 to October 2012, were included. Of these, 122 pts (47%) fulfilled the criteria for MetS. The median age of this group was significantly higher (71.3 vs. 69.38 years, p = 0.028). MetS prevalence was 50% in the control group. In pts who received ADT, prevalence was 44.8% after 6 months of ADT, 45.3% after 12–18 months, and 50% after ≥24 months (pns). Most pts (168/270; 62%) underwent DEXA. Of those tested, 78 (46.4%) had osteopenia and only 11 (6.5%) had osteoporosis. Conclusions The prevalence of MetS in pts with PCa treated with radical RT was higher (47%) than in the general population. However, there were no significant differences in the duration of ADT administration. The prevalence of osteoporosis was low. These findings suggest that the prevalence of MetS in PCa patients may be higher than previously reported. PMID:26549995

  16. Primary experimental results of wire-array Z-pinches on PTS

    Energy Technology Data Exchange (ETDEWEB)

    Huang, X. B., E-mail:; Zhou, S. T., E-mail:; Ren, X. D., E-mail:; Dan, J. K., E-mail:; Wang, K. L., E-mail:; Zhang, S. Q., E-mail:; Li, J., E-mail:; Xu, Q., E-mail:; Cai, H. C., E-mail:; Duan, S. C., E-mail:; Ouyang, K., E-mail:; Chen, G. H., E-mail:; Ji, C., E-mail:; Wang, M., E-mail:; Feng, S. P., E-mail:; Yang, L. B., E-mail:; Xie, W. P., E-mail:; Deng, J. J., E-mail: [Key Lab of Pulsed Power, Institute of Fluid Physics, CAEP, P.O. Box 919-108, Mianyang, Sichuan 621999 (China)


    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a multiterawatt pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%-90%) current to a short circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. In this paper, primary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 14.4-26.4 mm, and consisting of 132∼276 tungsten wires with 5∼10 μm in diameter. Multiple diagnostics were fielded to determine the characteristics of x-ray radiations and to obtain self-emitting images of imploding plasmas. X-ray power up to 80 TW with ∼3 ns FWMH is achieved by using nested wire arrays. The total x-ray energy exceeds 500 kJ and the peak radiation temperature is about 150 eV. Typical velocity of imploding plasmas goes around 3∼5×10{sup 7} cm/s and the radial convergence ratio is between 10 and 20.

  17. Variable length adjacent partitioning for PTS based PAPR reduction of OFDM signal

    Energy Technology Data Exchange (ETDEWEB)

    Ibraheem, Zeyid T.; Rahman, Md. Mijanur; Yaakob, S. N.; Razalli, Mohammad Shahrazel; Kadhim, Rasim A. [School of Computer and Communication Engineering, Universiti Malaysia Perlis, 02600 Arau, Perlis (Malaysia)


    Peak-to-Average power ratio (PAPR) is a major drawback in OFDM communication. It leads the power amplifier into nonlinear region operation resulting into loss of data integrity. As such, there is a strong motivation to find techniques to reduce PAPR. Partial Transmit Sequence (PTS) is an attractive scheme for this purpose. Judicious partitioning the OFDM data frame into disjoint subsets is a pivotal component of any PTS scheme. Out of the existing partitioning techniques, adjacent partitioning is characterized by an attractive trade-off between cost and performance. With an aim of determining effects of length variability of adjacent partitions, we performed an investigation into the performances of a variable length adjacent partitioning (VL-AP) and fixed length adjacent partitioning in comparison with other partitioning schemes such as pseudorandom partitioning. Simulation results with different modulation and partitioning scenarios showed that fixed length adjacent partition had better performance compared to variable length adjacent partitioning. As expected, simulation results showed a slightly better performance of pseudorandom partitioning technique compared to fixed and variable adjacent partitioning schemes. However, as the pseudorandom technique incurs high computational complexities, adjacent partitioning schemes were still seen as favorable candidates for PAPR reduction.

  18. Modified PTS with FECs for PAPR Reduction in MIMO-OFDM System with Different Subblocks and Subcarriers

    Directory of Open Access Journals (Sweden)

    Mukunthan Pandurangan


    Full Text Available Multiple input multiple output orthogonal frequency division multiplexing (MIMO-OFDM systems have been proposed in the recent past for providing high data-rate services over wireless channels. When combined with space time coding it provides the advantages of space-time coding and OFDM, resulting in a spectrally efficient wideband communication system. However, MIMO OFDM systems suffer with the problem of inherent high peak-to-average power ratio (PAPR due to the intersymbol interference between the subcarriers. In order to obtain optimal PAPR reduction using the partial transmitted sequence (PTS, the total search for the number of subblocks and the rotation factors must be accomplished. As the number of subblocks and rotation factors increases, PAPR reduction improves. The number of calculation increases as the number of subblocks increases, such that complexity increases exponentially and the process delay occurs simultaneously. In this paper, a generalised framework for PAPR reduction for MIMO OFDM systems based on modified PTS using forward error-correcting codes (FECs such as Turbo codes and Golay codes are employed. PAPR reduction is jointly optimised in both the real and imaginary part by use of fast Fourier transform (FFT algorithm in the modified PTS which can be utilized for finding the optimum phase weighting factors, and can achieve the lower PAPR and computational complexity of MIMO OFDM systems. The simulation results show that the combined FEC with modified PTS technique significantly provides better PAPR reduction with reduced computational complexity compared to original PTS technique in the MIMOOFDM systems.

  19. Audit and Assessment Studies

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Craig [Tlingit-Haida Regional Housing Authority, Juneau, AK (United States)


    Project to assess 46 low-income multifamily residences owned and managed by THRHA in up to 14 southeast Alaska communities. The Objective of project was to identify efficiency measures to reduce energy costs by 30% for low-income multifamily housing by; 1. Decreasing energy demand by increasing multifamily housing energy efficiency; 2. Reducing household energy consumption through energy conservation education and installation of energy upgrades; and 3. Projecting energy savings based on fossil fuel reduction to environmentally and economically benefit Tribal southeast communities

  20. Patient’s satisfaction after 2-piece inflatable penile prosthesis implantation: An Italian multicentric study

    Directory of Open Access Journals (Sweden)

    Giorgio Gentile


    Full Text Available Introduction: Penile prosthesis implant represents a valuable solution for pts with severe erectile dysfunction (ED, non-responders to medical management. The aim of our study was to evaluate the satisfaction of patients (pts after 2-pieces inflatable penile prosthesis (IPP. Aim of the study: to evaluate safety, reliability and post-operative patient’s satisfaction after implantation of two-pieces IPP. Materials and Methods: This retrospective multicentric analysis concerns a group of 42 patients undergone 2-pieces IPP implantation from November 2005 to November 2013, in four Centers of proven experience. As a first step, a detailed review of all clinical reports was performed. Secondly, every patient was asked to fill the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS specifically modified, in order to assess their own satisfaction after surgery and, its impact on patient’s quality of sexual life. Results: 42 pts were evaluated (AMS-Ambicor: 28; Coloplast- Excell: 14; mean age, at time of operation: 60,7 years; mean follow up: 27,6 months; etiology of ED: vascular 23,8%, diabetes 19%, La Peyronie D. 7,1%, consequence of radical prostatectomy 31%, consequence of other pelvic surgery 11,9%, spinal trauma 7%. Mean operative time: 117 ± 58 min, mean postoperative hospital stay 3 ± 1,6 days. Post operative short-term complications: 4 pts (9,5%. Post operative long-term complications: 4 pts (9,5%. Long-term functional results (Questionnaire: 71% of pts (30 reported regular use of the prosthesis, at least 1 time/week, the satisfaction was good in 42% of pts (18, quite good in 33,3% (14, quite bad in 2,4% (1, very bad in 7,1% (3, 6 pts (14,4% didn’t answer. Conclusions: 2 pieces IPP appears to be associated with a low complication rate and good satisfaction of pts especially in the elderly. It also assures satisfactory rates of aesthetics and functional results.

  1. Study of Ender’s Nailing in Shaft Femur Fractures of Older Children

    Directory of Open Access Journals (Sweden)

    Ladani HG


    Full Text Available Background: Fractures in shaft femur in children are relatively common. Various methods of treating these fractures starting from non operative to methods like closed intramedullary nailing are at our disposal. Traditionally non operative methods are acceptable and find wide acceptance even today in very young children. However in older children certain problems are encountered like failure to control angulation and shortening, prolonged immobilization which causes very much discomfort & the overgrowth phenomenon. In view of above difficulties, closed intramedullary nailing was attempted in older children and adolescents. I have tried to study 23 cases of shaft femur fractures in older children treated by Ender’s nails. Methodology: 22 pts., out of which one having bilateral # shaft femur (total 23 #s with age ranging from 7 to 16 yrs. were studied. 3 pts. having polio limbs studied separately. Fracture was in upper third shaft femur in 5 pts., middle third in 13 pts., lower third in 3pts. & involving more than one region in 2 pts. Fracture was transverse in 6 pts., spiral in 3 pts., oblique in 12 pts.& comminuted in 2 pts.. Results: Average union time was 10 weeks except in polio pts. where it was delayed. No nonunion, no infection. Excellent hip & knee movements in almost all pts. Out of 20 pts. ( except polio pts. limb length was equal in 17 pts., one pt. was having 1 cm. lengthening & 2 pts. were having shortening ( 1cm. & 2 cm.. Conclusion: Results of this study strongly favor the use of Ender’s nailing in shaft femur fractures in older children. Second surgery of implant removal is mandatory. Closed reduction can usually be achieved if surgery is performed earlier.

  2. Redução preliminar de itens da PTS versão 7 a 14 anos

    Directory of Open Access Journals (Sweden)

    Ito Patrícia do Carmo Pereira


    Full Text Available A Pavlovian Temperament Survey - PTS foi desenvolvida para avaliar a expressão comportamental das propriedades do Sistema Nervoso Central. Este estudo teve como objetivo iniciar o processo de aferição e redução de itens da PTS, versão 7 a 14 anos. Participaram da amostra 124 sujeitos de 7 a 14 anos, de ambos os sexos, os quais tiveram suas características temperamentais avaliadas pela PTS. O processo de redução e aferição constou de duas etapas: análise da correlação item total e análise fatorial exploratória. Resultados obtidos indicaram a permanência de 107 itens do total de 252 que inicialmente compunham a escala: 35 itens em FE (38,8%, 42 em FI (50% e 30 em MO (38,4%. Novos estudos se fazem necessários para uma melhor adequação dos itens ao contexto brasileiro, com ampliação da amostra para dar continuidade ao processo de aferição e redução de itens da PTS versão 7 a 14 anos.

  3. Thermal hydraulic evaluation for an experimental facility to investigate pressurized thermal shock (PTS) in CDTN/CNEN; Avaliacao termo-hidraulica da montagem experimental de choque termico pressurizado do CDTN/CNEN

    Energy Technology Data Exchange (ETDEWEB)

    Palmieri, Elcio T.; Navarro, Moyses A.; Aronne, Ivam D.; Terra, Jose L. [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte, MG (Brazil)


    The goal of the work presented in this paper is to provide necessary thermal hydraulics information to the design of an experimental installation to investigate the Pressurized Thermal Shock (PTS) to be implemented at Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN). The envisaged installation has a test section that represents, in a small scale, a pressure vessel of a nuclear reactor. This test section will be heated and then exposed to a PTS in order to evaluate the appearance and development of cracks. To verify the behavior of the temperatures of the pressure vessel after a sudden flood through the annulus, calculations were made using the RELAP5/MOD 3.2.2 gamma code. Different outer radiuses were studied for the annular region. The results showed that the smaller annulus spacing (20 mm) anticipates the wetting of the surface and produces a higher cooling of the external surface, which stays completely wet for a longer time. (author)

  4. Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1. (United States)

    Motley, A; Lumb, M J; Oatey, P B; Jennings, P R; De Zoysa, P A; Wanders, R J; Tabak, H F; Danpure, C J


    Alanine/glyoxylate aminotransferase 1 (AGT) is peroxisomal in most normal humans, but in some patients with the hereditary disease primary hyperoxaluria type 1 (PH1), AGT is mislocalized to the mitochondria. In an attempt to identify the sequences in AGT that mediate its targeting to peroxisomes, and to determine the mechanism by which AGT is mistargeted in PH1, we have studied the intracellular compartmentalization of various normal and mutant AGT polypeptides in normal human fibroblasts and cell lines with selective deficiencies of peroxisomal protein import, using immunofluorescence microscopy after intranuclear microinjection of AGT expression plasmids. The results show that AGT is imported into peroxisomes via the peroxisomal targeting sequence type 1 (PTS1) translocation pathway. Although the COOH-terminal KKL of human AGT was shown to be necessary for its peroxisomal import, this tripeptide was unable to direct the peroxisomal import of the bona fide peroxisomal protein firefly luciferase or the reporter protein bacterial chloramphenicol acetyltransferase. An ill-defined region immediately upstream of the COOH-terminal KKL was also found to be necessary for the peroxisomal import of AGT, but again this region was found to be insufficient to direct the peroxisomal import of chloramphenicol acetyltransferase. Substitution of the COOH-terminal KKL of human AGT by the COOH-terminal tripeptides found in the AGTs of other mammalian species (SQL, NKL), the prototypical PTS1 (SKL), or the glycosomal PTS1 (SSL) also allowed peroxisomal targeting, showing that the allowable PTS1 motif in AGT is considerably more degenerate than, or at least very different from, that acceptable in luciferase. AGT possessing the two amino acid substitutions responsible for its mistargeting in PH1 (i.e., Pro11-->Leu and Gly170-->Arg) was targeted mainly to the mitochondria. However, AGTs possessing each amino acid substitution on its own were targeted normally to the peroxisomes. This

  5. A PhD abstract presentation on Cluster Framework for Internet of People, Things and Services (IoPTS)

    DEFF Research Database (Denmark)

    Shinde, Gitanjali; Olesen, Henning


    The Internet of Things (IoT) is a revolutionary technology, where devices around us are capable of sensing, reacting, responding and working autonomously to provide services to the users /people, e.g. smart homes, enterprise, utilities and e-Health. In the IoT paradigm, every device...... will be connected to the Internet to provide services to the user. Bringing this together makes it relevant to talk about the "Internet of People, Things and Services (IoPTS)."However, managing such a huge number of devices is a major challenge for IoPTS. In any given context, a number of devices will work together...... to provide appropriate services to the user. Information sensed by the group of devices is raw and unstructured in nature due to heterogeneity, and hence there is a need of the mechanism that converts raw information into structured and machine-readable format. Furthermore, the group of devices must somehow...

  6. Industrial heat pump assessment study (United States)

    Chappell, R. N.; Priebe, S. J.; Wilfert, G. L.


    This report summarizes preliminary studies that assess the potential of industrial heat pumps for reduction of process heating requirements in industries receiving power from the Bonneville Power Administration (BPA). This project was initiated at the request of BPA to determine the potential of industrial heat pumps in BPA's service area. Working from known heat pump principles and from a list of BPA's industrial customers, the authors estimated the fuel savings potential for six industries. Findings indicate that the pulp and paper industry would yield the greatest fuel savings and increased electrical consumption. Assessments presented in this report represent a cooperative effort between The Idaho National Engineering Laboratory (INEL), and Battelle-Northwest Laboratories.

  7. Characterization of injection wells in a fractured reservoir using PTS logs, Steamboat Hills Geothermal Field, Nevada, USA

    Energy Technology Data Exchange (ETDEWEB)

    Goranson, Colin; Combs, Jim


    The Steamboat Hills Geothermal Field in northwestern Nevada, about 15 km south of Reno, is a shallow (150m to 825m) moderate temperature (155 C to 168 C) liquid-dominated geothermal reservoir situated in highly-fractured granodiorite. Three injection wells were drilled and completed in granodiorite to dispose of spent geothermal fluids from the Steamboat II and III power plants (a 30 MW air-cooled binary-type facility). Injection wells were targeted to depths below 300m to inject spent fluids below producing fractures. First, quasi-static downhole pressure-temperature-spinner (PTS) logs were obtained. Then, the three wells were injection-tested using fluids between 80 C and 106 C at rates from 70 kg/s to 200 kg/s. PTS logs were run both up and down the wells during these injection tests. These PTS surveys have delineated the subsurface fracture zones which will accept fluid. The relative injectivity of the wells was also established. Shut-in interzonal flow within the wells was identified and characterized.

  8. Development of Pneumatic Transfer Irradiation Facility (PTS no.1) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J


    A pneumatic transfer system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide and a delayed neutron counting system. The pneumatic transfer system (PTS no.1) involving a manual system and an semiautomatic system were reconstructed with new designs of a functional improvement at the HANARO research reactor in 2006. In this technical report, the conception, design, operation and control of these system (PTS no.1) was described. Also the experimental results and the characteristic parameters measured by a mock-up test, a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  9. Development of Pneumatic Transfer Irradiation Facility (PTS no.3) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J


    A pneumatic transfer system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide. The pneumatic transfer irradiation system (PTS no.3) involving a manual system and an semi-automatic system were reconstructed with new designs of a functional improvement at the HANARO research reactor and NAA laboratory of RI building in 2006. In this technical report, the design, operation and control of these system (PTS no.3) was described. Also the experimental results and the characteristic parameters measured from a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  10. Development of Pneumatic Transfer Irradiation Facility (PTS no.2) for Neutron Activation Analysis at HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Kim, S. H.; Sun, G. M.; Baek, S. Y.; Kim, H. R.; Kim, Y. J


    A pneumatic transfer irradiation system (PTS) is one of the most important facilities used during neutron irradiation of a target material for instrumental neutron activation analysis (INAA) in a research reactor. In particular, a fast pneumatic transfer system is essential for the measurement of a short half-life nuclide and a delayed neutron counting system. The pneumatic transfer irradiation system (PTS no.2) involving a manual system and an automatic system for delayed neutron activation analysis (DNAA) were reconstructed with new designs of a functional improvement at the HANARO research reactor in 2006. In this technical report, the conception, design, operation and control of PTS no.2 was described. Also the experimental results and the characteristic parameters measured by a mock-up test, a functional operation test and an irradiation test of these systems, such as the transfer time of irradiation capsule, automatic operation control by personal computer, delayed neutron counting system, the different neutron flux, the temperature of the irradiation position with an irradiation time, the radiation dose rate when the rabbit is returned, etc. are reported to provide a user information as well as a reactor's management and safety.

  11. Geology, Surficial - CLAY_ILITH_PTS_IN: Total Thickness of Clay in Indiana, Derived from the iLITH Water-Well Database (Indiana Geological Survey, Point Shapefile) (United States)

    NSGIC GIS Inventory (aka Ramona) — CLAY_ILITH_PTS_IN is a point shapefile that shows total thickness of clay, as derived from logs of water wells in the state of Indiana. (It presents the source data...

  12. Alflutop efficacy in chronic vertebrogenous lumbar ischialgia. A double blind placebo controlled study

    Directory of Open Access Journals (Sweden)

    O S Levin


    Full Text Available Objective. To assess efficacy and safety of intramuscular (im and paravertebral (pv alflutop injections in pts with chronic vertebrogenous lumbar ischialgia. Material and methods. 83 pts with lumbar ischialgia syndrome (44 male, 39 female aged 31 to 56 years (mean 43,1 ±5,2 years were included. Disease duration varied from I to 7 years (mean 3,5± 1,9 years, duration of the present exacerbation - from 1 to 4 months (mean 2.4±0,8 months. Vertebroneurologic diagnosis was made according to H. Hall criteria. Pts were randomized into 4 groups. 32 pts of group Al received im, 23 pts of group A2 - pv alflutop injections. 14 pts of group Bl and 14 pts of group B2 received im and pv placebo injections respectively. Treatment results were scored by the doctor. Pts assessed spine pain changes on visual analog scale. Quantitative assessment of verbal syndrome was performed with Waddle scale. Results. Im alflutop injections provided good or fair effect in 61%, pv - in 69% of pts (significantly better than placebo. Effect was evident during the first 2 weeks of treatment and persisted for 3 months after its termination. The best results were achieved in pts with facet syndrome, the worst - in spinal stenosis. Drug tolerability was good in both modes of administration.

  13. Portfolio assessment: practice teachers' early experience. (United States)

    Spence, William; El-Ansari, Walid


    Experience was recognised to be a vital source of learning as long ago as 1762 [Emile, Everyman, London, 1993] and reflection on practice experience may be one way forward in addressing nursing's anxieties concerning the practice theory gap. However, despite the acceptance that subjectivity in the process seems inevitable and potentially important, little is understood of the practitioner's experience of practice assessment. Two questionnaires sought the views of specialist community nursing practitioner (SCNP) programme (United Kingdom Central Council for Nursing, Midwifery and Health Visiting (UKCC) 2001) practice teachers (PTs) on the introduction of the portfolio approach to practice assessment. These were distributed to 62 and 76 PTs and the response rates were 32% and 50%, respectively. Responses of those PTs from the three specialisms participating in the piloting of the portfolio approach were compared with those using an existing approach. An action research method was adopted which attempted to use established theory to explain the challenges presented by the introduction of this approach and ultimately to raise the PT group's awareness of assessment issues. Both qualitative and quantitative data were collected and the findings support the use of the portfolio approach to practice assessment. The PT experience of portfolio use was found to be a largely positive one. PTs reported the utility of the portfolio in prompting student self-evaluation of learning. Concerns were expressed by PTs around the quality of portfolio evidence although many felt that it had promoted students' reflection on practice. Inter-PT reliability in practice assessment was identified as a topic for PT continuing professional development. Many sources of evidence, including patient feedback, were used by PTs in their assessment of students although PTs using the portfolio approach used less first-hand experience of students' practice in their assessments of competence, relying more

  14. National Children's Study Dietary Assessment Workshop (United States)

    The National Children's Study dietary assessment workshop was an opportunity for experts in dietary assessment methodology to gather and discuss the current state of knowledge about methodologies used to assess dietary intake during pregnancy, lactation, infancy, childhood, and adolescence.

  15. 冠心病并糖尿病患者氯吡格雷治疗后PTS 分子标志物变化及意义%Changes and Significance of PTS Molecular Markers after Treatment of Clopidogrel in Coronary Heart Disease Patients Combined with Diabetes

    Institute of Scientific and Technical Information of China (English)

    万妮娜; 马建林; 吴明; 马立宁; 李斌


    Objective To observe the changes and significance of prethrombotic state(PTS)molecular markers after treatment of clopidogrel in coronary heart disease(CHD)patients combined with non - insulin dependent diabetes mellitus(NIDDM). Methods PTS molecular markers were measured in 36 patients with stable angina(SA),38 pa-tients with unstable angina(UA),40 UA patients combined with NIDDM,who were given platelet ADP receptor antag-onist clopidogrel 75 mg/ d. PTS molecular markers were reexamined and clopidogrel resistance was measured 10 days later. Results ①There were more obvious changes of PTS molecular markers in patients with UA,especially in those combined with NIDDM before clopidogrel treatment. ②There were significant improvement of PTS molecular markers in patients in three groups after clopidogrel treatment. ③There were 18 cases with clopidogrel resistance and 96 cases without clopidogrel resistance in 114 cases. There were significant improvement of PTS in patients without clopidogrel resistance. However,there was no significant difference of PTS molecular markers before and after treatment in patients with clopidogrel resistance. Conclusion PTS in CHD patients combined with diabetes is more serious than CHD pa-tients without diabetes. PTS in patients with UA is more serious than that in patients with SA. PTS in patients with all types of CHD can be intervened by clopidogrel therapy. However,it is not effective in patients with clopidogrel resist-ance,which may be an important cause of poor prognosis in these patients.%目的:观察冠心病(CAD)并2型糖尿病(NIDDM)患者经过血小板 ADP 受体拮抗剂治疗后血栓形成前状态(PTS)分子标志物的变化及意义。方法对36例稳定性心绞痛(SA)、38例不稳定性心绞痛(UA)、40例 UA 合并 NIDDM 患者的 PTS 分子标志物进行检测,均给予血小板 ADP 受体拮抗剂氯吡格雷75 mg/ d,10 d 后复查 PTS 分子标志物,同时测定有无氯吡

  16. Numerical simulation of the direct contact condensation phenomena for PTS-related in single and combined-effect thermal hydraulic test facilities using TransAT CMFD code

    Energy Technology Data Exchange (ETDEWEB)

    Kadi, Rabah, E-mail: [Laboratory for Thermal-Hydraulics, Nuclear Research Center of Birine (Algeria); Aissani, Slimane [Hydrocarbons and Chemistry Faculty, University of Boumerdes (Algeria); Bouam, Abdellah [Laboratory for Thermal-Hydraulics, Nuclear Research Center of Birine (Algeria)


    Highlights: • TransAT CMFD code application to DCC phenomenon. • LEIS methodology to predict the condensing steam flow rate. • Validation of interfacial phase-change heat transfer and turbulence models. • Correction of damping function at the free surface region. • Numerical validation of previous models using LIM and KAERI & KAIST test facilities. - Abstract: The use of CFD for the industrial studies related to PTS, including DCC is already possible; improvements of the two-phase modeling capabilities have to be undertaken to qualify the codes for the simulation of such flows. The DCC in horizontally stratified flow regime constitutes very considerable challenge exercises for a computational fluid dynamics (CFD) simulation of the thermal hydraulics PTS phenomenon because the interplay between turbulence and interfacial heat and mass transfer problem. The main purpose of our study is to investigate numerically the DCC in horizontally stratified steam water flow in a 2D and 3D channel using TransAT CMFD code. The new methodology known as Large-Eddy & Interface (LEIS) have been implemented for treatment of turbulence combined with interface tracking ITM (level set approach). Among of the so-called ‘coarse-grained’ ITM's models, the modified original surface divergence has been chosen as well as the treatment of the turbulence by URANS and VLES. This contribution addressed on the validation of interfacial phase-change heat transfer and turbulence models with special correction of the damping function at the free surface for single and combined-effect thermal hydraulic studies for LIM and KAERI & KAIST test facilities. The LIES methodology was found to apply successfully to predict the condensing steam flow rate in the all cases of the LIM test case involving a Smooth to Wavy turbulent, concurrent stratified steam-water flow in a 2D channel. The CMFD TransAT code predicting capability is analyzed, comparing the liquid temperature and to much the

  17. A manual therapy intervention improves symptoms in patients with carpal tunnel syndrome: a pilot study. (United States)

    Maddali Bongi, Susanna; Signorini, Massimo; Bassetti, Massimo; Del Rosso, Angela; Orlandi, Martina; De Scisciolo, Giuseppe


    In carpal tunnel syndrome (CTS), manual therapy interventions (MTI) reduce tissue adhesion and increase wrist mobility. We evaluated the efficacy of a MTI in relieving CTS signs and symptoms. Twenty-two CTS patients (pts) (41 hands) were treated with a MTI, consisting in 6 treatments (2/week for 3 weeks) of soft tissues of wrist and hands and of carpal bones. Pts were assessed for hand sensitivity, paresthesia, hand strength, hand and forearm pain, night awakening; Phalen test, thenar eminence hypotrophy and Boston Carpal Tunnel Questionnaire (BCTQ) Symptom Severity Scale (SSS) and Functional Status Scale (FSS). Median nerve was studied by sensory nerve conduction velocity (SNCV) and distal motor latency (DML). CTS was scored as minimal, mild, medium, severe and extreme. We considered as control group the same pts assessed before treatment: at baseline (T0a) and after 12 weeks (T0b). Pts were evaluated at the end of treatment (T1) and after 24-week (T2) follow-up. At T0b, versus T0a, forearm pain and Phalen test positivity were increased and hand strength reduced (p < 0.05). BCTQ-SSS and BCTQ-FSS scores improved at T1 versus T0b (p < 0.05) with the amelioration maintained at T2. At T1, the number of pts with paresthesia, night awakening, hypoesthesia, Phalen test, hand strength reduction and hand sensitivity was reduced with the lacking of symptoms maintained at T2 (p < 0.05). No changes in SNCV, DML and CTS scoring were shown. MTI improved CTS signs and symptoms, with benefits maintained at follow-up. Thus, it may be valid as a conservative therapy.

  18. 变形链球菌磷酸转移酶在不同蔗糖浓度下的差异性表达%Differential and qutantitive analysis of mRNA expression of pts from S.mutans

    Institute of Scientific and Technical Information of China (English)

    陆玉; 刘天佳; 杨锦波


    目的 检测变形链球菌不同毒力株的致龋性与磷酸转移酶(pts)系统各编码基因表达变化的关系.方法 选取高毒力株临床分离株502与低毒力株标准株UA159,以real-time PCR方法检测在1%和2%蔗糖浓度下,变形链球菌磷酸转移酶系统各编码基因的表达变化.结果 1%蔗糖浓度,高毒力株和低毒力株的scrA、scrB、ptsH、ptsI的表达均明显升高,而ptsK的表达受到抑制;2%蔗糖浓度,各基因的调节方向与上述相反.结论 磷酸转移酶系统可能增加变形链球菌在低糖浓度环境下的致龋力.%Objective To determine the expression level of genes which code pts under various conditions in different strains of S. Mutans. Methods S. Mutans of clinical isolations with different EPS producibility and UA159 were selected. Under 1% sucrose and 2% sucrose, the relative quantity of scrA, scrB,ptsI,ptsH and ptsK's mRNA of the two strains were examined by real-time PCR methods. Results In 1% sucrose, the expression levels of scrA,scrB ,ptsI,ptsH were increased in both strains, the level of ptsK was decreased. Expression levels of ptsH and ptsl were increased more in the strain with stronger virulence. In 2% sucrose the expression levels of scrA scrB ptsI ptsH were decreased the level of ptsK was increased in both strains. Conclusion PTS strengthened the cariogenicity of S. Mutans in low sucrose condition.

  19. Genetic characterization of the CcpA-dependent, cellobiose-specific PTS system comprising CelB, PtcB and PtcA that transports lactose in Lactococcus lactis IL1403. (United States)

    Aleksandrzak-Piekarczyk, Tamara; Polak, Jolanta; Jezierska, Beata; Renault, Pierre; Bardowski, Jacek


    Lactose metabolism is one of the most important areas of research on Lactic Acid Bacteria (LAB). In rapidly acidifying industrial Lactococcus lactis strains, lactose is transported by a lactose-specific phosphotransferase system (PTS) encoded by a plasmid. However, an alternative lactose catabolic pathway was evidenced in the plasmid-cured, and thus initially lactose-negative L. lactis IL1403. We showed that in this strain the chromosomally-encoded cellobiose-specific PTS system comprising the celB, ptcB and ptcA genes is also able to transport lactose. By expression studies in the wild type IL1403 strain and IBB550, its ccpA-deficient derivative, we demonstrated that celB, ptcB and ptcA are tightly regulated by the general catabolite repression system, whereas celB additionally requires the presence of cellobiose to be fully induced. The comparison of expression levels of sugar catabolic genes indicated that the efficiency of CcpA-mediated catabolic repression depends on conservation of the cre sequence, and that in the case of perfect matching with the cre consensus, CcpA still drives a strong repression even under non-repressing conditions.

  20. Assessing observational studies of medical treatments

    Directory of Open Access Journals (Sweden)

    Butani Yogita


    Full Text Available Abstract Background Previous studies have assessed the validity of the observational study design by comparing results of studies using this design to results from randomized controlled trials. The present study examined design features of observational studies that could have influenced these comparisons. Methods To find at least 4 observational studies that evaluated the same treatment, we reviewed meta-analyses comparing observational studies and randomized controlled trials for the assessment of medical treatments. Details critical for interpretation of these studies were abstracted and analyzed qualitatively. Results Individual articles reviewed included 61 observational studies that assessed 10 treatment comparisons evaluated in two studies comparing randomized controlled trials and observational studies. The majority of studies did not report the following information: details of primary and ancillary treatments, outcome definitions, length of follow-up, inclusion/exclusion criteria, patient characteristics relevant to prognosis or treatment response, or assessment of possible confounding. When information was reported, variations in treatment specifics, outcome definition or confounding were identified as possible causes of differences between observational studies and randomized controlled trials, and of heterogeneity in observational studies. Conclusion Reporting of observational studies of medical treatments was often inadequate to compare study designs or allow other meaningful interpretation of results. All observational studies should report details of treatment, outcome assessment, patient characteristics, and confounding assessment.

  1. 6-PTS 并联机器人机构逆向运动学分析与仿真*1%Inverse kinematics analysis and simulation of 6-PTS parallel robot

    Institute of Scientific and Technical Information of China (English)



    Objective—To put forward the algorithm of kinematic relationship between the parallel robot components.Methods—The composite joint of 6-PTS parallel robot's structure was equivalently processed into single DOF (degree of freedom)joint,then D-H (Denavic-Hartenberg)method was used to define the local coordinate system and kinematic parameters of each linkage.Finally mecha-nism constraint equations was established according to the motion equivalence condition and the solu-tion was obtained with reverse homogeneous transformation.Results and Conclusion—The variables of all joint and the position of each linkage were solved successively.On this basis,the influence coeffi-cient theory was utilized to build the transitive relationships of the velocity and acceleration between moving platform and each linkage to provide the basis for the dynamic modeling and control problem of the mechanism.%目的:提出建立并联机器人构件之间运动学关系的算法。方法将6-PTS 并联机器人机构的复合关节等效地处理成单自由度关节,利用 D-H(Denavic-Hartenberg)方法定义每个连杆的局部坐标系和运动学参数,根据运动等同性条件建立机构约束方程,利用逆向齐次变换的方法求解。结果与结论依次求解出全部关节变量和每个连杆的位置表示,在此基础上,应用影响系数理论,建立了动平台与每个连杆之间的速度和加速度的传递关系,为该机构的动力学建模及控制等问题提供了基础。

  2. Assessment of critical thinking: a Delphi study. (United States)

    Paul, Sheila A


    Nurse educators are responsible for preparing nurses who critically analyze patient information and provide meaningful interventions in today's complex health care system. By using the Delphi research method, this study, utilized the specialized and experiential knowledge of Certified Nurse Educators. This original Delphi research study asked Certified Nurse Educators how to assess the critical-thinking ability of nursing students in the clinical setting. The results showed that nurse educators need time, during the clinical experience, to accurately assess each individual nursing student. This study demonstrated the need for extended student clinical time, and a variety of clinical learning assessment tools.

  3. Study on Assessment of Mine Environments

    Institute of Scientific and Technical Information of China (English)

    WU Qiang; LI Wei; LI Ruijun


    Mine environmental evaluation is the key to mine environmental study. On the basis of the characteristics of the mine environmental problems, they are classified into (1) three wastes problem, (2) ground distortion, (3) contradiction among mine drainage, water supply, ecological environment,(4) desertification, and (5) soil erosion. The evaluation is the basis of mine environmental problem classification and investigation, mine environmental rehabilitation, and the information system constructed can be used for subsequent research of evaluation techniques. A synthetic assessment of the 5 kinds of mine environmental problems can be divided into single-factor or multi-factor synthetic assessments; while by the viewpoint of time, the mine environmental assessment can be classified as the historical assessment, the current status assessment and the forecasting assessment.

  4. The usefulness of contrast during exercise echocardiography for the assessment of systolic pulmonary pressure

    Directory of Open Access Journals (Sweden)

    Cordeiro Ana


    Full Text Available Abstract Background The systolic pulmonary artery pressure (PAPs can be accurately estimated, non-invasively, using continuous-wave Doppler (CWD ultrasound measurement of the peak velocity of a tricuspid regurgitant (TR jet. However, it is often difficult to obtain adequate tricuspid regurgitation signals for measurement of PAPs, what could lead to its underestimation. Therefore, utilization of air-blood-saline contrast has been implemented for the improvement of Doppler signal in several clinical contexts. It is now recommended in the evaluation of patients with pulmonary hypertension. Physical activity is severely restricted in patients with PAH, being exertional dypnea the most typical symptom. Exercise stress echo-Doppler imaging allows assessment of the response to exercise. It is an excellent screening test for patients with suspected PAH. Our purpose was to evaluate the value and accuracy of agitated saline with blood contrast echocardiography, in the improvement of the Doppler signal, to quantify PAPs during treadmill exercise-echocardiography. Purpose To evaluate the value of contrast echocardiography, using agitated saline with blood, in the improvement of the Doppler signal used to quantify the pulmonary artery systolic pressure during exercise. Methods From a total of 41 patients (pts, we studied 38 pts (93%, 35 women, aged 54 ± 12 years-old. 27 with the diagnosis of systemic sclerosis, 10 with history of pulmonary embolism and one patient with a suspected idiopathic PAH, who were referred to the Unity of Heart Failure and Pulmonary Hypertension for screening of PAH. According to the Unity protocol, a transthoracic echocardiogram was made, in left decubitus (LD, with evaluation of right ventricle-right atria gradient (RV/RAg. A peripheral venous access was obtained, with a 3-way stopcock and the patients were placed in orthostatism (O, with a new evaluation of RV/RAg. Exercise echocardiography (EE was begun, with evaluation of RV

  5. Mineral bone density comparative assessment in patients with systemic lupus erythematosus treated and not treated with glucocorticoids

    Directory of Open Access Journals (Sweden)

    L A Archakova


    Full Text Available Objective. To compare bone mineral density (BMD in pts with systemic lupus erythematosus (SLE, treated and untreated by glucocorticoids (GC. Matherial and Methods. 30 females with reliable SLE were examined (APA, 1982, 15 had GC (prednisolone 7.5-60mg/day, median cumulative dose 10.7±6.6g (1st group, 15 others did not take GC (2nd group. Groups were comparable by age, SLE course duration, body weight. All were females with normal menses period. BMD was assessed in low back vertebral region and femoral neck in standard projections on dichromatic X-ray densitometer QDR-1000 Plus (Hologic, USA in absolute values (g/cm2 and T-index. Results. BMD in low back was statistically reliably lower in the 1st group as compared with the 2nd (0,918±0,118 and 1,036±0,156; p=0,027. In the left femoral neck there were no differences in mineralization of bone tissue (0,769±0,167 and 0,807±0,227; p=0,568, BMD decreasing in the studied bone region reliably prevailed among pts of the 1st group (n=ll as compared with the 2nd (n=2 (p=0.003. Conclusion. SLE pis treated by GC demonstrated reliably lower indices of BMD in LI-L4 as compared with pts who were not treated by GC.

  6. Perspectives of contained chondroprotective therapy of osteoarthritis. Results of an open randomized study of Artra preparation in patients with gonarthrosis

    Directory of Open Access Journals (Sweden)

    L L Alexeeeva


    Full Text Available Objective. To assess efficacy and safety of combined chondroprotective ARTRA preparation ("Unipharm Inc" USA in pts with gonarthrosis Material and methods. 90 pts with knee joint osteoarthritis (OA, 11-111 radiological stage according to Kellgren-Lawrence and prominent pain syndrome requiring regular treatment with NSAIDs were included. 45 pts received ARTRA and diclofenac sodium, 45 control pts were treated only with diclofenac sodium during 6 months. Clinical examination was performed before, after 30, 120 and 180 days of treatment. Efficacy was assessed according to conventional criteria of assessment drugs assigned for OA treatment. Results. ARTRA proved to be a new effective drug for OA treatment. It provided decrease of pain and stiffness in damaged joints so as significant improvement of functional state. Systematical ARTRA administration allows decreasing NSAID dose or completely withdrawing such drugs in many pts. ARTRA showed good tolerability and safety so as long aftereffect.

  7. Assessment of joint pain in teenagers with juvenile arthritis

    Directory of Open Access Journals (Sweden)

    T A Shelepina


    Full Text Available Assessment of joint pain in teenagers with juvenile arthritisObjective. To assess mean total pain score in teenagers with juvenile arthritis (JA and its values in groups differing on sex, variant of course, activity measures, degree of functional disturbances. To assess advisability of application of these parameters in real clinical practice. Material and methods. 73 pts with JA (mean age 14,7±1,7 years, mean disease duration7,2±4,4 years were included. 18 from them had systemic, 42 – polyarticular and 13 – olygoarticular variant. 16 pts were examined repeatedly with interval exceeding one year. Total quantity of examinations was 94. 17 pts were examined at admission and at discharge. Pain was measured on visual analog scale (VAS and on McGill Pain Questionnaire (83 examinations including 3 scale: sensor (description of pain, affective (their influence on emotional state and evaluative (verbal assessment of pain intensity. General health assessment on VAS was performed in 59 pts (in 8 from them at admission and at discharge. Summary mean measures and their values in groups differing in sex, course variant, activity measure, functional class at pts admission to and at discharge from the Institute of Rheumatology of RAMS. Statistical treatment was performed with Biomed program(descriptive statistic, χ2, Student’s pared test. Results. Mean pain score on VAS in all teenagers with JA was 31,3±17,3. It was significantlyhigher in boys with systemic variant (in comparison with polyarticular, in pts with ESR elevation above 30, in pts with functional class 3 and higher at admission to the department. Pain score was significantly lower in pts with olygoarticular variant in comparison with mean value and with value in polyarthritis. Pain above 70 mm on VAS was found in pts with polyarticular damage in systemic and polyarticular variants in active phase of the disease and in severe functional disability. Summated (on sensor and affective scales


    Directory of Open Access Journals (Sweden)

    Rudy Badrudin


    Full Text Available This research analyze the effect of regional autonomy to the interest of college’s student candidate to continue studying in Sleman Regency which research’s samples for major program’s chosen was Accounting, Management, and Economics in UII, UAJY, UPNVY, and STIE YKPN. The result of research with Boston Consulting Group (BCG Matrix shows that each major program in four universities and college was in different quadrant. Therefore, each university and college has to choose different development strategic specifically even for each major programs in each university and college, so that the major programs in four universities and college in Sleman Regency could grow and rise.

  9. Restriction fragment differential display of pediocin-resistant Listeria monocytogenes 412 mutants shows consistent overexpression of a putative beta-glucoside-specific PTS system. (United States)

    Gravesen, A; Warthoe, P; Knochel, S; Thirstrup, K


    Pediocin PA-1, which is a bacteriocin produced by lactic acid bacteria, has potential as a biopreservative of food. However, such use may lead to the development of resistance in the target organism. Gene expression in two independent pediocin-resistant mutants of Listeria monocytogenes 412 was compared to the original isolate by restriction fragment differential display PCR (RFDD-PCR). This method amplifies cDNA restriction fragments under stringent PCR conditions, enabled by the use of specific primers complementary to ligated adaptor sequences. RFDD-PCR was very well suited for analysis of listerial gene expression, giving reproducible PCR product profiles. Three gene fragments having increased expression in both resistant mutants were identified. All three had homology to components of beta-glucoside-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS), one fragment having homology to enzyme II permeases, and the two others to phospho-beta-glucosidases. Overexpression of the putative PTS system was consistently observed in 10 additional pediocin-resistant mutants, isolated at different pH, salt content and temperature. The results suggest that RFDD-PCR is a strong approach for the analysis of prokaryotic gene expression and that the putative beta-glucoside-specific PTS system is involved in mediating pediocin resistance.

  10. Special Education Faculty Needs Assessment Study Implications (United States)

    Smith, D.D.; Tyler, N.; Montrosse, B.E.; Young, C.; Robb, S.M.


    This paper presents the highlights of the Special Education Faculty Needs Assessment Study (SEFNA). Actions taken after the release of The 2001 Faculty Shortage Study demonstrate that supply-and-demand imbalances can be improved. The projected shortage of special education faculty will directly and negatively affect students with disabilities and…

  11. Value of case studies in disaster assessment? (United States)

    Grynszpan, Delphine; Murray, Virginia; Llosa, Silvia


    Case studies can be useful in assessing and learning lessons from emergency situations. In this paper, different uses for disaster case studies, are explored with identification of potential pitfalls that should be avoided. In addition, ways to improve the rigor and significance of case studies are suggested. Case studies can be used as examples or as a research tool. If conducted properly, they can provide robust and compelling results. It is argued that sharing a common guide to conducting and writing case studies among all disaster risk reduction professionals could improve the quality of case study reports and thereby strengthen their value in advancing the prevention, preparedness, and management of disasters and emergencies.

  12. Geology, Surficial - SAND_ILITH_PTS_IN: Total Thickness of Sand and Gravel in Indiana, Derived from the iLITH Water-Well Database (Indiana Geological Survey, Point Shapefile) (United States)

    NSGIC GIS Inventory (aka Ramona) — SAND_ILITH_PTS_IN is a point shapefile that shows total thickness of sand, as derived from logs of water wells in the state of Indiana. (It presents the source data...

  13. Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies

    Institute of Scientific and Technical Information of China (English)

    Jiang-quan ZHOU; Zhi-qiang TANG; Jin-nan ZHANG; Jing-cheng TANG


    Aim: To study the in vivo and in vitro metabolism and the effect of para-toluene-sulfonamide (PTS) on cytochrome P450 enzymes (CYP450). Methods: Total C YP450 and microsome protein content were determined after iv pretreatment of rats with PTS. CYP-specific substrates were incubated with rat liver microsomes. Specific CYP isoform activities were determined by using HPLC. CYP chemical inhibitors added to the incubation mixture were used to investigate the principal CYP isoforms involved in PTS metabolism. The effect of PTS on CYP isoforms was investigated by incubating PTS with specific substrates. Results: The groups treated with 33 and 99 mg/kg per d PTS, respectively, had a total CYP content of 0.66±0.17 and 0.60±0.12 nmol/mg. The Km and Vmax were 92.2 μmol/L and 0.0137 nmol/min per mg protein. CYP2C7, CYP2D1 and CYP3A2 might contribute to PTS metabolism in the rat liver. The inhibitory effects of sulfaphenazole and ketoconazole on PTS metabolism were shown to have a mixed mechanism, whereas PTS metabolism was inhibited noncompetitively by quinidine. PTS had little effect on the activities of the selected CYP isoforms. Conclusion: Generally speaking, it is relatively safe for PTS to be co-administered with other drugs. However, care should be taken when administering PTS with CYP inhibitors and the substrates of CYP2C, CYP2D and CYP3A.

  14. Impact of new traumatic or stressful life events on pre-existing PTSD in traumatized refugees: results of a longitudinal study (United States)

    Schock, Katrin; Böttche, Maria; Rosner, Rita; Wenk-Ansohn, Mechthild; Knaevelsrud, Christine


    Background A significant proportion of trauma survivors experience an additional critical life event in the aftermath. These renewed experiences of traumatic and stressful life events may lead to an increase in trauma-related mental health symptoms. Method In a longitudinal study, the effects of renewed experiences of a trauma or stressful life event were examined. For this purpose, refugees seeking asylum in Germany were assessed for posttraumatic stress symptoms (PTS), Posttraumatic Stress Diagnostic Scale (PDS), anxiety, and depression (Hopkins Symptom Checklist [HSCL-25]) before treatment start as well as after 6 and 12 months during treatment (N=46). Stressful life events and traumatic events were recorded monthly. If a new event happened, PDS and HSCL were additionally assessed directly afterwards. Mann–Whitney U-tests were performed to calculate the differences between the group that experienced an additional critical event (stressful vs. trauma) during treatment (n=23) and the group that did not (n=23), as well as differences within the critical event group between the stressful life event group (n=13) and the trauma group (n=10). Results Refugees improved significantly during the 12-month period of our study, but remained severely distressed. In a comparison of refugees with a new stressful life event or trauma, significant increases in PTS, anxiety, and depressive symptoms were found directly after the experience, compared to the group without a renewed event during the 12 months of treatment. With regard to the different critical life events (stressful vs. trauma), no significant differences were found regarding overall PTS, anxiety, and depression symptoms. Only avoidance symptoms increased significantly in the group experiencing a stressful life event. Conclusion Although all clinicians should be aware of possible PTS symptom reactivation, especially those working with refugees and asylum seekers, who often experience new critical life events, should

  15. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen


    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...

  16. Postpartum depression: identifying associations with bipolarity and personality traits. Preliminary results from a cross-sectional study in Poland. (United States)

    Dudek, Dominika; Jaeschke, Rafał; Siwek, Marcin; Mączka, Grzegorz; Topór-Mądry, Roman; Rybakowski, Janusz


    The goals of this study have been to determine the prevalence of the bipolar spectrum features in the population of women with postpartum depression (PPD) symptoms, as well as to analyze the personality differences between putative 'unipolar' and 'bipolar' PPD subjects. The sample enrolled into the cross-sectional study consisted of 344 women at 6-12 weeks postpartum. The authors used the Edinburgh Postnatal Depression Scale (EPDS; cut-off score: 13 pts.) for the assessment of the PPD symptoms, the Mood Disorder Questionnaire (MDQ; cut-off scores: 7 or 8 pts.) for diagnosing the bipolar features, and the NEO-Five Factor Inventory (NEO-FFI) for the assessment of personality traits. The EPDS-positive subjects were more likely to score positively on the MDQ, as compared to the EPDS-negative ones. The EPDS-positive subjects who also scored ≥8 pts. on the MDQ were characterized by higher index of neuroticism, as compared to those who scored positively on the EPDS only. The results suggest that the presence of PPD symptoms is related to significantly higher scores of bipolarity and neuroticism. The more robust trait of neuroticism might be a marker of the 'bipolar' PPD, as compared to the 'unipolar' form of the disorder.

  17. A Study of Career Planning Assessments


    Firkola, Peter


    This paper provides an overview of career planning assessments. Background on key career concepts is first introduced. A number of career planning assessments are then examined. These assessments included reviewing ones personal history, interest inventories, values assessments, personality assessments, and aptitude tests. The importance and limitations of these career assessments is then discussed.

  18. Risk Assessment Study for Storage Explosive

    Directory of Open Access Journals (Sweden)

    S. S. Azhar


    Full Text Available In Malaysia, there has been rapidly increasing usage in amount of explosives due to widely expansion in quarrying and mining industries. The explosives are usually stored in the storage where the safety precaution had given high attention. As the storage of large quantity of explosive can be hazardous to workers and nearby residents in the events of accidental denotation of explosives, a risk assessment study for storage explosive (magazine had been carried out. Risk assessment study had been conducted in Kimanis Quarry Sdn. Bhd, located in Sabah. Risk assessment study had been carried out with the identification of hazards and failure scenarios and estimation of the failure frequency of occurrence. Analysis of possible consequences of failure and the effects of blast waves due to the explosion was evaluated. The risk had been estimated in term of fatalities and eardrum rupture to the workers and public. The average individual voluntary risk for fatality to the workers at the quarry is calculated to be 5.75 x 10-6 per person per year, which is much lower than the acceptable level. Eardrum rupture risk calculated to be 3.15 x 10-6 per person per year for voluntary risk. There is no involuntary risk found for fatality but for eardrum rupture it was calculated to be 6.98 x 10-8 per person per year, as given by Asian Development Bank.

  19. Impact of new traumatic or stressful life events on pre-existing PTSD in traumatized refugees: results of a longitudinal study

    Directory of Open Access Journals (Sweden)

    Katrin Schock


    Full Text Available Background: A significant proportion of trauma survivors experience an additional critical life event in the aftermath. These renewed experiences of traumatic and stressful life events may lead to an increase in trauma-related mental health symptoms.Method: In a longitudinal study, the effects of renewed experiences of a trauma or stressful life event were examined. For this purpose, refugees seeking asylum in Germany were assessed for posttraumatic stress symptoms (PTS, Posttraumatic Stress Diagnostic Scale (PDS, anxiety, and depression (Hopkins Symptom Checklist [HSCL-25] before treatment start as well as after 6 and 12 months during treatment (N=46. Stressful life events and traumatic events were recorded monthly. If a new event happened, PDS and HSCL were additionally assessed directly afterwards. Mann–Whitney U-tests were performed to calculate the differences between the group that experienced an additional critical event (stressful vs. trauma during treatment (n=23 and the group that did not (n=23, as well as differences within the critical event group between the stressful life event group (n=13 and the trauma group (n=10.Results: Refugees improved significantly during the 12-month period of our study, but remained severely distressed. In a comparison of refugees with a new stressful life event or trauma, significant increases in PTS, anxiety, and depressive symptoms were found directly after the experience, compared to the group without a renewed event during the 12 months of treatment. With regard to the different critical life events (stressful vs. trauma, no significant differences were found regarding overall PTS, anxiety, and depression symptoms. Only avoidance symptoms increased significantly in the group experiencing a stressful life event.Conclusion: Although all clinicians should be aware of possible PTS symptom reactivation, especially those working with refugees and asylum seekers, who often experience new critical life

  20. Hegemonic Masculinity in Sport Education: Case Studies of Pre-Service Physical Education Teachers with Teaching Orientations (United States)

    Chen, YuChun; Curtner-Smith, Matthew D.


    Previous research had indicated that pre-service teachers (PTs) with coaching orientations reinforced sexism and masculine bias while employing the sport education (SE) model. The purpose of the current study was to examine whether or not and the degree to which SE delivered by PTs with teaching orientations served to combat or reinforce sexism…

  1. The Healthy Communities Study Nutrition Assessments (United States)

    Ritchie, Lorrene D.; Wakimoto, Patricia; Woodward-Lopez, Gail; Thompson, Frances E.; Loria, Catherine M.; Wilson, Dawn K.; Kao, Janice; Crawford, Patricia B.; Webb, Karen L.


    Multifaceted community interventions directed at improving food environments are emerging, but their impact on dietary change and obesity prevalence has not been documented adequately. The Healthy Communities Study (HCS) is seeking to identify characteristics and combinations of programs and policies that are associated with children’s diets and obesity-related outcomes in various types of communities across the U.S. The purpose of this paper is to describe the methods used in 2013–2015 in the HCS to assess dietary intake, school nutrition environments, and other nutrition-related behaviors. The conceptual framework of the HCS is based on the socioecological model and behaviors shown in previous studies to be related to obesity in children-guided selection of domains. Nine domains were identified as essential measures of nutrition in the HCS: (1) intake of selected foods and beverages; (2) food patterns and behaviors; (3) social support; (4) home environment; (5) school environment; (6) community environment; (7) breastfeeding history; (8) household food insecurity; and (9) dieting behaviors and body image. Children’s dietary intake was assessed using a dietary screener and up to two automated 24-hour recalls. Dietary-related behaviors were assessed by a survey administered to the parent, child, or both, depending on child age. School nutrition measures were obtained from a combination of school staff surveys and researcher observations. Information from these measures is expected to contribute to a better understanding of “what is working” to improve the dietary behaviors that are likely to prevent obesity and improve health in children. PMID:26384936

  2. Probabilistic assessment of pressurised thermal shocks

    Energy Technology Data Exchange (ETDEWEB)

    Pištora, Vladislav, E-mail:; Pošta, Miroslav; Lauerová, Dana


    Rector pressure vessel (RPV) is a key component of all PWR and VVER nuclear power plants (NPPs). Assuring its integrity is therefore of high importance. Due to high neutron fluence the RPV material is embrittled during NPP operation. The embrittled RPV may undergo severe loading during potential events of the type of pressurised thermal shock (PTS), possibly occurring in the NPP. The resistance of RPV against fast fracture has to be proven by comprehensive analyses. In most countries (with exception of the USA), proving RPV integrity is based on the deterministic PTS assessment. In the USA, the “screening criteria” for maximum allowable embrittlement of RPV material, which form part of the USA regulations, are based on the probabilistic PTS assessment. In other countries, probabilistic PTS assessment is performed only at research level or as supplementary to the deterministic PTS assessment for individual RPVs. In this paper, description of complete probabilistic PTS assessment for a VVER 1000 RPV is presented, in particular, both the methodology and the results are attached. The methodology corresponds to the Unified Procedure for Lifetime Assessment of Components and Piping in WWER NPPs, “VERLIFE”, Version 2008. The main parameters entering the analysis, which are treated as statistical distributions, are as follows: -initial value of material reference temperature T{sub 0}, -reference temperature shift ΔT{sub 0} due to neutron fluence, -neutron fluence, -size, shape, position and density of cracks in the RPV wall, -fracture toughness of RPV material (Master Curve concept is used). The first step of the analysis consists in selection of sequences potentially leading to PTS, their grouping, establishing their frequencies, and selecting of representative scenarios within all groups. Modified PSA model is used for this purpose. The second step consists in thermal hydraulic analyses of the representative scenarios, with the goal to prepare input data for the


    Directory of Open Access Journals (Sweden)

    Gunadi H. Sulistyo


    Full Text Available Abstract: Assessing Non English Department Students’ Mastery of Academic Content Area Reading. This study addresses mainly college students’comprehension on academic texts. It involves 400 respondents of three state and three private universities in Malang with study programs with ‘high, ‘fair’, and ‘low’ bases on the proportion of the study programs accredited A by the National Board of Accreditation (BAN. Quantitative data were analyzed descriptively and comparatively. The results show reading com­prehension of most respondents ranges from ‘avarage’ to ‘low’. Most word attack skills and text content attack skills are low. Text structure attack skills are not adequately mastered. The respondents’ compre­hension across state universities does not significantly differ, but there is a difference across private univer­sities, limited to certain private universities. A significant difference between the comprehension of stu­dents of state universities and private universities and a significant difference between the comprehension of science and social studies students are evidenced. Most respondents are not yet ready for academic comprehension of English. Abstrak: Asesmen Kemampuan Membaca Pemahaman Teks Akademik Mahasiswa Non-Jurusan Bahasa Inggris. Penelitian ini bertujuan untuk mengungkap penguasaan keterampilan memahami teks akademik mahasiswa. Penelitian ini menggunakan rancangan expost facto yang melibatkan 400 responden dari tiga PTN dan tiga PTS di Malang yang memiliki proporsi program studi terakreditasi A oleh BAN pada kategori ’tinggi’, ’sedang’, ’rendah’. Data kuantitatif dianalisis secara deskriptif dan komparatif. Hasil penelitian menunjukkan bahwa tingkat penguasaan keterampilan membaca sebagian besar responden cenderung rendah. Sebagian besar word attack skills masih rendah penguasaannya. Tidak ada satu pun keterampilan text structure attack skills yang sudah dikuasai secara memadai. Penguasaan

  4. System Losses and Assessment Trade Study

    Energy Technology Data Exchange (ETDEWEB)

    David Shropshire; Steve Piet; Nick Soelberg; Robert Cherry; Roger Henry; David Meikrantz; Greg Teske; Eric Shaber; Candido Pereira


    This Advanced Fuel Cycle Initiative (AFCI) study has developed new analysis methods to examine old and new technology options toward the goal of improving fuel cycle systems. We have integrated participants and information from AFCI Systems Analysis, Transmutation Fuels, Separations, and Waste Form Campaigns in the Systems Losses and Assessment Trade Study. The initial objectives of this study were to 1) increase understanding of system interdependencies and thereby identify system trade-offs that may yield important insights, 2) define impacts of separations product purity on fuel manufacture and transmutation reactivity, 3) define impacts from transuranic (TRU) losses to waste, 4) identify the interrelationships involved in fuels and separations technology performance, and 5) identify system configuration adjustments with the greatest potential for influencing system losses. While bounding and analyzing this initial problem, we also identified significantly higher-level programmatic drivers with broad implications to the current fuel cycle research charter and the general issue of a DOE complex wide need for a comprehensive and integrated nuclear material management as addressed by the new DOE Order 410.2 titled “Management of Nuclear Materials”. The initial modeling effort developed in this study for a much smaller subset of material (i.e., commercial fuel) and a selected transmutation scheme (i.e., fast reactor recycling) is a necessary first step towards examining a broader set of nuclear material management options, dispositioning strategies and integrated waste management options including potential areas of research leverage. The primary outcome from this initial study has been an enhanced integration among Campaigns and associated insights and analysis methods. Opportunities for improved understanding between the groups abound. The above lanthanide-actinide example highlights the importance of evaluating options via integration across the Campaigns

  5. Coupled RELAP5, 3D CFD and FEM analysis of postulated cracks in RPVs subjected to PTS loading

    Energy Technology Data Exchange (ETDEWEB)

    González-Albuixech, V.F., E-mail: [Paul Scherrer Institut (PSI), Nuclear Energy and Safety Department, Structural Integrity Group, Villigen CH-5232 (Switzerland); Qian, G., E-mail: [Paul Scherrer Institut (PSI), Nuclear Energy and Safety Department, Structural Integrity Group, Villigen CH-5232 (Switzerland); Sharabi, M. [Paul Scherrer Institut (PSI), Nuclear Energy and Safety Department, Structural Integrity Group, Villigen CH-5232 (Switzerland); Mechanical Power Engineering Department, Faculty of Engineering, Mansoura University, 35516 Mansoura (Egypt); Niffenegger, M.; Niceno, B.; Lafferty, N. [Paul Scherrer Institut (PSI), Nuclear Energy and Safety Department, Structural Integrity Group, Villigen CH-5232 (Switzerland)


    Highlights: • RPV fracture mechanics model based on RELAP5. • RPV fracture mechanics model based on CFD. • RPV fracture mechanics analysis. - Abstract: The fracture mechanic analysis of a reactor pressure vessel subjected to pressurized thermal shock loading is one of the most important issues for the assessment of life time extension of a nuclear power plant. The most severe scenario occurs during cold water injection in the cold leg due to a Loss-Of-Coolant Accident (LOCA). In the present study a comprehensive fracture mechanics analysis is performed. Two hypothetical LOCAs are assumed for an adopted reference design of a two-loop Pressurized Water Reactor. Boundary conditions obtained from the RELAP5 code are used as input for Computational Fluid Dynamics (CFD) simulations. For the structural integrity analysis, submodeling technique and the eXtended Finite Element Method (XFEM) based on temperatures calculated by CFD are applied. The results from the 3D FEM calculations are compared to those from a simplified axisymmetric model based on axisymmetric thermal hydraulic model results. The analysis identifies the worst crack orientation and location. It also proves that a complete model is needed for a correct analysis as the simplified model is not conservative and fails to describe accurately the local plume effect.

  6. Formative peer assessment in a CSCL environment: A case study.

    NARCIS (Netherlands)

    Prins, Frans; Sluijsmans, Dominique; Kirschner, Paul A.; Strijbos, Jan Willem


    In this case study our aim was to gain more insight in the possibilities of qualitative formative peer assessment in a computer supported collaborative learning (CSCL) environment. An approach was chosen in which peer assessment was operationalized in assessment assignments and assessment tools that

  7. Alflutop clinical efficacy in vertebral osteochondrosis (12-mohth study

    Directory of Open Access Journals (Sweden)

    V N Hodyrev


    Full Text Available Objective. To study clinical efficacy of aiflutop (A in lumbar osteochondrosis (LO with chronic back pain syndrome. Material and Methods. 32 pts with LO were included. 14 from them (group 1 during a year received 2 courses of A intramuscular injections (I ml/day, 30 ml total and nonsteroidal anti-inflammatory drugs (NSAIDs if necessary. 18 pts (group 2 received NSAIDs only. Clinical examination of pts was performed at the stert of the study, before and after each A course and in 3 months after the last course. Results. Pain in the spine at rest and forward bending significantly decreased in group 1 pts (p<0,05 after each A course. Full pain disappearance after the first A course was achieved in 7,1% and after the second course - in 35,7% of group I pts and was not shown in control group. Significant stepped decrease of Thomayer's test value (p<0,00l was also shown in group 1: 3,6 times decrease in comparison with baseline was achieved in 3 months after completion of treatment with A. During treatment period these pts showed 2-2,5 times increase of static and dynamic spine load (according to Vxdel chronic inability index. 42,9% of group I pts stopped NSAIDs after A treatment completion. Only 5,6% of control group pts stopped NSAIDs during follow up. A tolerability was good. It can be combined with any other medications the pts received due to comorbid diseases.

  8. Undergraduate study in psychology: Curriculum and assessment. (United States)

    Norcross, John C; Hailstorks, Robin; Aiken, Leona S; Pfund, Rory A; Stamm, Karen E; Christidis, Peggy


    The undergraduate curriculum in psychology profoundly reflects and shapes the discipline. Yet, reliable information on the undergraduate psychology curriculum has been difficult to acquire due to insufficient research carried out on unrepresentative program samples with disparate methods. In 2014, APA launched the first systematic effort in a decade to gather national data on the psychology major and program outcomes. We surveyed a stratified random sample of department chairs/coordinators of accredited colleges and universities in the United States that offer undergraduate courses and programs in psychology. A total of 439 undergraduate psychology programs (45.2%) completed the survey. This article summarizes, for both associate and baccalaureate programs, the results of the Undergraduate Study in Psychology. Current practices concerning the introductory course, the courses offered, core requirements, the psychology minor, and tracks/concentrations are presented. The frequency of formal program reviews and program-level assessment methods are also addressed. By extending prior research on the undergraduate curriculum, we chronicle longitudinal changes in the psychology major over the past 20 years.

  9. Assessing English proficiency for university study

    CERN Document Server

    Read, John


    This book focuses on strategies and procedures for assessing the academic language ability of students entering an English-medium university, so that those with significant needs can have access to opportunities to enhance their language skills.

  10. The Present Absence: Assessment in Social Studies Classrooms (United States)

    Torrez, Cheryl A.; Claunch-Lebsack, Elizabeth Ann


    In this article, first the authors describe the aims of and a definition of social studies education and classroom assessment. Second, the authors provide an overview of issues related to classroom assessment followed by trends in social studies classrooms and assessment. Then the authors address essential systems and best practices related to…

  11. Energy security assessment framework and three case-studies



    This chapter provides a novel framework for assessing energy security and illustrates its application by the Global Energy Assessment, the IEA Model for Short-term energy security and in several studies of long-term global energy security.

  12. Assessment Leaders' Perspectives of Institutional Cultures of Assessment: A Delphi Study (United States)

    Fuller, Matthew; Henderson, Susan; Bustamante, Rebecca


    Institutional cultures of assessment are praised as beneficial to student learning. Yet, extant studies have not explored the theoretical foundations and pragmatic approaches to shaping cultures of assessment. The researchers used the Delphi method to explore 10 higher education assessment leaders' attitudes and theoretical perspectives regarding…

  13. Potential impact of enhanced fracture-toughness data on fracture mechanics assessment of PWR vessel integrity for pressurized thermal shock

    Energy Technology Data Exchange (ETDEWEB)

    Dickson, T.L.; Theiss, T.J.


    The Heavy Section Steel Technology (HSST) Program is involved with the generation of enhanced fracture-initiation toughness and fracture-arrest toughness data of prototypic nuclear reactor vessel steels. These two sets of data are enhanced because they have distinguishing characteristics that could potentially impact PWR pressure vessel integrity assessments for the pressurized-thermal shock (PTS) loading condition which is a major plant-life extension issue to be confronted in the 1990's. A series of large-scale fracture-mechanics experiments have produced crack-arrest (K{sub Ia}) data with the distinguishing characteristic that the values are considerably above 220 MPA {center dot} {radical}m. The implicit limit of the ASME Code and the limit used in the Integrated Pressurized Thermal Shock (IPTS) studies. Currently, the HSST Program is planning experiments to verify and quantify for A533B steel the distinguishing characteristic of elevated the distinguishing characteristic of elevated initiation-fracture toughness for shallow flaws which has been observed for other steels. The results of the analyses indicated that application of the enhanced K{sub Ia} data does reduce the conditional probability of failure P(F{vert bar}E); however, it does not appear to have the potential to significantly impact the results of PTS analyses. The application of enhanced fracture-initiation-toughness data for shallow flaws also reduces P(F{vert bar}E), and does appear to have a potential for significantly affecting the results of PTS analyses. 19 refs., 11 figs., 1 tab.

  14. Assessing biofuel crop invasiveness: a case study.

    Directory of Open Access Journals (Sweden)

    Christopher Evan Buddenhagen

    Full Text Available BACKGROUND: There is widespread interest in biofuel crops as a solution to the world's energy needs, particularly in light of concerns over greenhouse-gas emissions. Despite reservations about their adverse environmental impacts, no attempt has been made to quantify actual, relative or potential invasiveness of terrestrial biofuel crops at an appropriate regional or international scale, and their planting continues to be largely unregulated. METHODOLOGY/PRINCIPAL FINDINGS: Using a widely accepted weed risk assessment system, we analyzed a comprehensive list of regionally suitable biofuel crops to show that seventy percent have a high risk of becoming invasive versus one-quarter of non-biofuel plant species and are two to four times more likely to establish wild populations locally or be invasive in Hawaii or in other locations with a similar climate. CONCLUSIONS/SIGNIFICANCE: Because of climatic and ecological similarities, predictions of biofuel crop invasiveness in Hawaii are applicable to other vulnerable island and subtropical ecosystems worldwide. We demonstrate the utility of an accessible and scientifically proven risk assessment protocol that allows users to predict if introduced species will become invasive in their region of interest. Other evidence supports the contention that propagule pressure created by extensive plantings will exacerbate invasions, a scenario expected with large-scale biofuel crop cultivation. Proactive measures, such as risk assessments, should be employed to predict invasion risks, which could then be mitigated via implementation of appropriate planting policies and adoption of the "polluter-pays" principle.

  15. Wound assessment tools and nurses’ needs: an evaluation study


    Greatrex-White, Sheila; Moxey, Helen


    The purpose of this study was to ascertain how well different wound assessment tools meet the needs of nurses in carrying out general wound assessment and whether current tools are fit for purpose. The methodology employed was evaluation research. In order to conduct the evaluation, a literature review was undertaken to identify the criteria of an optimal wound assessment tool which would meet nurses’ needs. Several freely available wound assessment tools were selected based on predetermin...

  16. 新的降低OFDM系统峰均比的PTS技术%New PTS technique for PAPR reduction in OFDM system

    Institute of Scientific and Technical Information of China (English)

    周建新; 贾振红; 何迪; 覃锡忠; 李涛; 赵君凯


    为有效降低OFDM系统峰均功率比,以最大效率开发利用电力线通信资源,提出一种新的降低峰均比的部分传输序列技术,采用微正则退火算法优化相位因子.仿真结果表明,该算法以较快的收敛速度取得较优的相位因子序列,显著降低了正交频分复用系统的峰均比,提高了电力线通信系统的性能.%In order to reduce the Peak to Average Power Ratio (PAPR) of Orthogonal Frequency Division Multiplexing (OFDM) system and develop the resource of Power Line Communication (PLC) efectively, this paper proposes a new Partial Transmit Seqence(PTS) technique.The technique presents Microcanonical Annealing (MA) algorithm to optimize phase factor.Simulation result shows that the algorithm can get the excellent phase factor with fast convergence speed,and the PAPR of the OFDM system is reduced remarkably which improves the performance of PLC effectively.

  17. Cumulative assessment : Strategic choices to influence students' study effort

    NARCIS (Netherlands)

    Kerdijk, Wouter; Tio, Rene A.; Mulder, B. Florentine; Cohen-Schotanus, Janke


    Background: It has been asserted that assessment can and should be used to drive students' learning. In the current study, we present a cumulative assessment program in which test planning, repeated testing and compensation are combined in order to influence study effort. The program is aimed at hel

  18. Wound assessment tools and nurses' needs: an evaluation study. (United States)

    Greatrex-White, Sheila; Moxey, Helen


    The purpose of this study was to ascertain how well different wound assessment tools meet the needs of nurses in carrying out general wound assessment and whether current tools are fit for purpose. The methodology employed was evaluation research. In order to conduct the evaluation, a literature review was undertaken to identify the criteria of an optimal wound assessment tool which would meet nurses' needs. Several freely available wound assessment tools were selected based on predetermined inclusion and exclusion criteria and an audit tool was developed to evaluate the selected tools based on how well they met the criteria of the optimal wound assessment tool. The results provide a measure of how well the selected wound assessment tools meet the criteria of the optimal wound assessment tool. No tool was identified which fulfilled all the criteria, but two (the Applied Wound Management tool and the National Wound Assessment Form) met the most criteria of the optimal tool and were therefore considered to best meet nurses' needs in wound assessment. The study provides a mechanism for the appraisal of wound assessment tools using a set of optimal criteria which could aid practitioners in their search for the best wound assessment tool.

  19. Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study

    Directory of Open Access Journals (Sweden)

    Riess Hanno


    Full Text Available Abstract Background Cachexia is a common problem in patients (pts suffering from upper gastrointestinal cancer. In addition, most of these patients suffer from malabsorption and stenosis of the gastrointestinal tract due to their illness. Various methods of supplementary nutrition (enteral, parenteral are practised. In patients with advanced pancreatic cancer (APC, phase angle, determined by bio-electrical impedance analysis (BIA, seems to be a survival predictor. The positive influence of BIA determinate predictors by additional nutrition is currently under discussion. Methods To examine the impact of additional parenteral nutrition (APN we assessed outpatients suffering from APC and progressive cachexia. The assessment based on the BIA method. Assessment parameters were phase angle, ECM/BCM index (ratio of extracellular mass to body cell mass, and BMI (body mass index. Patients suffering from progressive weight loss in spite of additional enteral nutritional support were eligible for the study. Results Median treatment duration in 32 pts was 18 [8-35] weeks. Response evaluation showed a benefit in 27 pts (84% in at least one parameter. 14 pts (43.7% improved or stabilised in all three parameters. The median ECM/BCM index was 1.7 [1.11-3.14] at start of APN and improved down to 1.5 [1.12-3.36] during therapy. The median BMI increased from 19.7 [14.4-25.9] to 20.5 [15.4-25.0]. The median phase angle improved by 10% from 3.6 [2.3-5.1] to 3.9 [2.2-5.1]. Conclusions We demonstrated the positive impact of APN on the assessed parameters, first of all the phase angle, and we observed at least a temporary benefit or stabilisation of the nutritional status in the majority of the investigated patients. Based on these findings we are currently investigating the impact of APN on survival in a larger patient cohort. Trial registration Identifier: NCT00919659

  20. Are failures of anterior cruciate ligament reconstruction associated with steep posterior tibial slopes? A case control study

    Institute of Scientific and Technical Information of China (English)

    Li Yue; Hong Lei; Feng Hua; Wang Qianqian; Zhang Hui; Song Guanyang


    Background Recently,increasing number of literature has identified the posterior tibial slope (PTS) as one of the risk factors of primary anterior cruciate ligament (ACL) injury.However,few studies conceming the association between failure of ACL reconstruction (ACLR) and PTS have been published.The objective of this study was to explore the association between the failure of ACLR and PTS at a minimum of two years follow-up.Methods Two hundred and thirty eight eligible patients from June 2009 to October 2010 were identified from our database.A total of 20 failure cases of ACLR and 20 randomly selected controls were included in this retrospective study.The demographic data and the results of manual maximum side-to-side difference with KT-1000 arthrometer at 30° of knee flexion and pivot-shift test before the ACLR and at the final follow-up were collected.The medial and lateral PTSs were measured using the magnetic resonance imaging (MRI) scan,based on Hudek's measurement.A comparison of PTS between the two groups was performed.Results The overall failure rate of the present study was 8.4%.Of the 40 participants,the mean medial PTS was 4.1°±3.2° and the mean lateral PTS was 4.6°±2.6°.The medial PTS of the ACLR failure group was significantly steeper than the control group (3.5°±2.5° vs.6.1°±2.1°,P=0.000).Similarly,the lateral PTS of the ACLR failure group was significantly steeper than the control group (2.9°±2.1 ° vs.5.5°±3.0°,P=0.006).For medial PTS ≥5°,the odds ratio of ACLR failure was 6.8 (P=0.007); for lateral PTS ≥5°,the odds ratio of ACLR failure was 10.8 (P=0.000).Conclusion Both medial and lateral PTS were significantly steeper in failures of ACLR than the control group.Medial or lateral PTS ≥5° was a new risk factor of ACLR failure.

  1. Quality of assessments within reach: Review study of research and results of the quality of assessments

    NARCIS (Netherlands)

    Maassen, N.A.M.; Otter, den D.; Wools, S.; Hemker, B.T.; Straetmans, G.J.J.M.; Eggen, T.J.H.M.


    Educational tests and assessments are important instruments to measure a student’s knowledge and skills. The question that is addressed in this review study is: “which aspects are currently considered as important to the quality of educational assessments?” Furthermore, it is explored how this infor

  2. Risk factors for post-thrombotic syndrome in patients with a first deep venous thrombos

    NARCIS (Netherlands)

    Tick, L.W.; Kramer, M.H.H.; Rosendaal, F.R.; Faber, W.R.; Doggen, C.J.M.


    Background: Post-thrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT). Objectives: To determine the risk of PTS after DVT and to assess risk factors for PTS. Methods: Patients were recruited from the Multiple Environmental and Genetic Assessment (MEGA) study of risk fa

  3. Assessment of Correspondent Banks Case Study

    Directory of Open Access Journals (Sweden)

    Abeer F.A.A. Abbadi


    Full Text Available Problem statement: This study aims at evaluating corresponding banks in Jordan. Characterizing the goals, instruments and profitability under unfavorable conditions of financial setbacks and unfair competition among banks. Focuses on the feasibility and profitability of Philadelphia Investment Bank in its international trade via its Correspondent banks. Approach: Problems and setbacks shall be screened out; reasoned and appropriate optimal recommendations are to be presented. Results: The study followed the analytical approach and depended on “History Documents” and “In depth Interview” techniques and puts a major emphasis on the fact that correspondent banking has become an essential cornerstone of international business amid the new era of world trade, globalization, external competition and cartels from the major opponents to Jordanian Banks, the main conclusion is realized the importance of correspondent banks in the international trade, so Philadelphia bank benefited from correspondent banks for the cheap cost of market entry and services were tailored to the scale of required locale. But there was no big investment in staff facilities. And there are setbacks in dealing with correspondent banks, such as fund delay in reaching destinations on time. Moreover, Jordanian banks have suffered in general from these correspondent banks because they deal with these correspondent banks individually. Conclusion/Recommendations: The recommendation of the study is, it is the time to consider solidification and forming one financial block, or a sort of cartel and face these correspondent banks in one unit. They are also called for developing collective strategies. Small banks should merge and form huge capital blocks. Another strategy is that Jordanian banks should minimize the reliance on foreign banks and should develop their own, by establishing international branches abroad to help financing their international activities.

  4. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne


    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second

  5. Contribution of recurrent venous thrombosis and inherited thrombophilia to the pathogenesis of postthrombotic syndrome. (United States)

    Kreidy, Raghid


    Postthrombotic syndrome (PTS) is a common complication of deep vein thrombosis. This study aims to assess the role of recurrent venous thrombosis and inherited thrombophilia in the pathogenesis of PTS. A series of 206 patients diagnosed with lower extremity venous thrombosis were retrospectively reviewed. The PTS was observed in 30.58% of the patients. Recurrent venous thrombosis was identified in 3.4% of the patients without PTS and in 33.3% of patients with PTS (P thrombophilia alone or in association with recurrent venous thrombosis was more commonly detected when PTS was moderate to severe (P = .04 and thrombophilia is present either alone or in association with recurrent venous thrombosis.

  6. Higher Education Quality Assessment in China: An Impact Study (United States)

    Liu, Shuiyun


    This research analyses an external higher education quality assessment scheme in China, namely, the Quality Assessment of Undergraduate Education (QAUE) scheme. Case studies were conducted in three Chinese universities with different statuses. Analysis shows that the evaluated institutions responded to the external requirements of the QAUE…

  7. Three Reflections on Assessing Safety Training Needs: A Case Study (United States)

    Sleezer, Catherine M.; Kelsey, Kathleen D.; Wood, Thomas E.


    Needs assessment plays an important role in training and human performance improvement efforts, but the literature contains little research on this topic. This study extended previous research on the Performance Analysis for Training (PAT) model of needs assessment by examining its implementation to determine environmental and occupational health…

  8. Dynamic assessment versus static assessment: A study of reading comprehension ability in Iranian EFL learners


    Nazari, Behzad; Mansouri, Saeed


    This study extends traditional or static assessment of reading comprehension in foreign language contexts and applies dynamic assessment (DA) to the development of learners’ reading ability. To homogenize the research population (N= 250), an Oxford Placement Test (OPT) was administered. On the basis of the test results, the population was sorted into three groups of reading-low, reading-mid, and reading-high students. The participants of this study were a sample of 30 participants with the lo...

  9. Assessing dance: A phenomonological study of formative assessment in dance education

    Directory of Open Access Journals (Sweden)

    Ninnie Andersson


    Full Text Available This article includes a study that examines how formative assessment in dance education is constituted in three Swedish upper secondary schools. The starting-point for the study is life-world phenomenology.  A phenomenological way of thinking entails that the human being is intersubjective, linked with and within the world and that learning requires the bodily subject´s active experience. To turn towards the things themselves and to be open and adherent to things in the world is a basic rule and the starting point for research within phenomenology. This study is based on empirical material from observations of the phenomenon formative assessment in dance. Spiegelberg´s philosophical method was used as a base for phenomenological analysis. The analysis results in three themes: modes of communication, dance-related knowledge and function of formative assessment. Formative assessment was observed in the study to commonly involve teachers´ verbal communication and visualisation. The assessment practice is a continuous activity and very rarely involves any kind of self-assessment or tests. The results were discussed and related to a life-world phenomenological view of learning and earlier research.

  10. Assessing the first wave of epidemiological studies of nanomaterial workers

    Energy Technology Data Exchange (ETDEWEB)

    Liou, Saou-Hsing, E-mail: [National Health Research Institutes, National Institute of Environmental Health Sciences (China); Tsai, Candace S. J. [Colorado State University, Department of Environmental and Radiological Health Science (United States); Pelclova, Daniela [Charles University in Prague, Department of Occupational Medicine, First Faculty of Medicine (Czech Republic); Schubauer-Berigan, Mary K.; Schulte, Paul A. [National Institute for Occupational Safety and Health (United States)


    The results of early animal studies of engineered nanomaterials (ENMs) and air pollution epidemiology suggest that it is important to assess the health of ENM workers. Initial epidemiological studies of workers’ exposure to ENMs (<100 nm) are reviewed and characterized for their study designs, findings, and limitations. Of the 15 studies, 11 were cross-sectional, 4 were longitudinal (1 was both cross-sectional and longitudinal in design), and 1 was a descriptive pilot study. Generally, the studies used biologic markers as the dependent variables. All 11 cross-sectional studies showed a positive relationship between various biomarkers and ENM exposures. Three of the four longitudinal studies showed a negative relationship; the fourth showed positive findings after a 1-year follow-up. Each study considered exposure to ENMs as the independent variable. Exposure was assessed by mass concentration in 10 studies and by particle count in six studies. Six of them assessed both mass and particle concentrations. Some of the studies had limited exposure data because of inadequate exposure assessment. Generally, exposure levels were not very high in comparison to those in human inhalation chamber studies, but there were some exceptions. Most studies involved a small sample size, from 2 to 258 exposed workers. These studies represent the first wave of epidemiological studies of ENM workers. They are limited by small numbers of participants, inconsistent (and in some cases inadequate) exposure assessments, generally low exposures, and short intervals between exposure and effect. Still, these studies are a foundation for future work; they provide insight into where ENM workers are experiencing potentially adverse effects that might be related to ENM exposures.

  11. Progress and Case Study on Probabilistic Assessment of Reactor Pressure Vessels under Pressurized Thermal Shock%承压热冲击下反应堆压力容器的概率评定进展与案例分析

    Institute of Scientific and Technical Information of China (English)

    高增梁; 李曰兵; 雷月葆


    A certain type of transients may cause the pressurized thermal shock(PTS) in the reactor pressure vessels(RPV) in pressurized water reactors(PWR) and may result in problem of structural integrity of RPV with flaws. The structural integrity assessment methods for RPV under PTS conditions are reviewed. The research progress and situation about these methods, especially probabilistic assessment, are introduced. Probabilistic assessment which uses the probabilistic fracture mechanics(PFM) analysis approach is reviewed, including uncertainty analysis (probability of detection, flaw characterization models, fracture property data, et al.), numerical calculating method on the failure probability, et al. Main PFM computational computer codes for PTS are evaluated. A PFM program is developed to calculate the failure probability. Two typical PTS transients for RPV and their structural integrities are analyzed. The results show that the failure probability for the RPV under these PTS transients is lower than the required value of nuclear safety for the design life of 60 years. Combined with Chinese nuclear power development, a few pieces of advices are proposed for probabilistic assessment of RPV structural integrity under PTS transients.%在压水堆核电站运行中,某些工况可能会使反应堆压力容器(Reactor pressure vessels, RPV)经受承压热冲击(Pressurized thermal shock, PTS)瞬态,这给含缺陷RPV的结构完整性带来了一定的挑战。简要介绍含缺陷RPV在PTS条件下的筛选准则及其结构完整性评定方法,重点阐述 PTS 下含缺陷 RPV 的概率评定方法。概率评定方法采用概率断裂力学(Probabilistic fracture mechanics, PFM)分析,主要内容包括不确定因素统计分析(裂纹检出率、裂纹尺寸、材料性能等)、裂纹启裂模型及穿透模型等。此外,还对适用于PTS分析的典型PFM程序进行评价。在此基础上,针对典型RPV利用自主开发的PFM程序进行两个


    Institute of Scientific and Technical Information of China (English)

    解慧琪; 杨志明; 屈艺; 秦廷武; 李秀群


    Objective To analysis the proliferation properties and telomerase activity of human embryonic tendon cells transformed by ptsA58H plasmid cultured in vitro continuously. Methods The 40th, 70th, and 75th passages of transformed human embryonic tendon cells (THETC) were adopted. The collagen secretion of THETC was detected by immunohistochemical methods, the growth curve of different passages of THETC was compared, and chromosome karyotype was analyzed. Total RNA of THETC were extracted to detect human telomerase reverse transcriptase (hTERT) mRNA expression by RT-PCR technique. Results When THETC were subcultured to 70 passages, the morphological characteristics of cells changed and began replicative senescence. THETC still could secret type Ⅰcollagen normally. The chromosome of THETC was heteroploid (2n=94). There were no hTERT mRNA expression. Conclusion SV40 transfection can not make human embryonic tendon cells immortalization, on the other hand, human embryonic tendon cells transformed by ptsA58H plasmid has no tendency of malignant transformation.%目的分析体外长期传代ptsA58H质粒转染人胚腱细胞的增殖能力及端粒酶活性。方法选用连续传代培养的第40代、第70代、第75代转化人胚腱细胞,免疫组化染色观察细胞分泌胶原类型,比较细胞生长曲线,并行染色体核型分析,流式细胞术检测细胞增殖周期,提取细胞总RNA,RT-PCR二步法检测细胞人端粒酶逆转录酶mRNA表达。结果转化人胚腱细胞传代至70代以后,细胞形态发生改变,出现复制衰老现象。细胞仍具有正常分泌Ⅰ型胶原的能力,转化人胚腱细胞染色体呈异倍性(2n=94)。转化人胚腱细胞无人端粒酶逆转录酶mRNA特异扩增带,无端粒酶活性表达。结论单纯SV40转染不能使人胚腱细胞永生化,同时也说明转化人胚腱细胞无恶性转化倾向。

  13. Surveying Assessment in Experiential Learning: A Single Campus Study

    Directory of Open Access Journals (Sweden)

    Thomas Yates


    Full Text Available The purpose of this study was to determine the methods of experiential assessment in use at a Canadian university and the extent to which they are used. Exploring experiential assessment will allow identification of commonly used methods and facilitate the development of best practices of assessment in the context of experiential learning (EL at an institutional level. The origins of EL are found in the work of Dewey (1938, later modified by Kolb and Fry (1975. Experiential methods include: experiential education, service learning problem-based learning and others such as action learning, enquiry-based learning, and case studies. Faculty currently involved in EL at the participating university were invited to complete an online survey about their teaching and assessment methods. This paper will share the results and analysis of the EL inventory survey.

  14. CHASE assessment of the North Sea – a pilot study

    DEFF Research Database (Denmark)

    Green, N.; Andersen, Jesper; Høgåsen, T.;

    In this pilot study, hazardous substances in the North Sea were assessed and classified using the HELCOM Chemical Substances Status Assessment Tool (CHASE). The study was based on monitoring by Belgium, Denmark, France, Germany, the Netherlands, Norway, Sweden and the United Kingdom. Together, 1350...... assessment and classification of “hazardous substances status”. This can be in particular advantageous for use in remedial action plan and, in particular, for the sciencebased evaluation of whether the North Sea is undisturbed by hazardous substances....... locations (1155 for sediment and 195 for biota) were used resulting in 966 matrices sampled in the open-sea and 506 in coastal areas. CHASE is a multi-metric indicator-based tool developed for the HELCOM integrated thematic assessment of hazardous substances in the Baltic Sea. CHASE produces an integrated...

  15. Assessment

    Institute of Scientific and Technical Information of China (English)

    Geoff Brindley


    @@ Introduction TERMINOLOGY AND KEY CONCEPTS The term assessment refers to a variety of ways of collecting information on a learner's language ability or achievement. Although testing and assessment are often used interchangeably, the latter is an umbrella term encompassing measurement instruments administered on a ‘one-off’ basis such as tests, as well as qualitative methods of monitoring and recording student learning such as observation, simulations of project work. Assessment is also distinguished from evaluation which is concerned with the overall language programme and not just with what individual students have learnt. Proficiency assessment refers to the assessment of general language abilities acquired by the learner independent of a course of study.This kind of assessment is often done through the administration of standardised commercial language-proficency tests. On the other hand, assessment of achievement aims to establish what a student had learned in relation to a particular course or curriculum (thus frequently carried out by the teacher) .Achievement assesssment may be based either on the specific content of the course or on the course objectives (Hughes 1989).

  16. Assessing the relevance of ecotoxicological studies for regulatory decision making

    NARCIS (Netherlands)

    Rudén, Christina; Adams, Julie; Ågerstrand, Marlene; Brock, Theo C.M.; Poulsen, Veronique; Schlekat, Christian E.; Wheeler, James R.; Henry, Tala R.


    Regulatory policies in many parts of the world recognize either the utility of or the mandate that all available studies be considered in environmental or ecological hazard and risk assessment (ERA) of chemicals, including studies from the peer-reviewed literature. Consequently, a vast array of d

  17. An Empirical Study of a Solo Performance Assessment Model (United States)

    Russell, Brian E.


    The purpose of this study was to test a hypothesized model of solo music performance assessment. Specifically, this study investigates the influence of technique and musical expression on perceptions of overall performance quality. The Aural Musical Performance Quality (AMPQ) measure was created to measure overall performance quality, technique,…

  18. A physiotherapy triage assessment service for people with low back disorders: evaluation of short-term outcomes

    Directory of Open Access Journals (Sweden)

    Bath B


    Full Text Available Brenna Bath, Punam PahwaCollege of Medicine, University of Saskatchewan, Saskatoon, CanadaPurpose: To determine the short-term effects of physiotherapy triage assessments on self-reported pain, functioning, and general well-being and quality of life in people with low back-related disorders.Methods: Participants with low back–related complaints were recruited from those referred to a spinal triage assessment program delivered by physiotherapists (PTs. Before undergoing the triage assessment, the participants completed a battery of questionnaires covering a range of sociodemographic, clinical, and psychosocial features. The study used the Numeric Pain Rating Scale (NPRS, the Oswestry Disability Index (ODI, and the Medical Outcomes Survey 36-item short-form version 2 (SF-36v2 to assess self-reported pain, function, and quality of life. Baseline measures and variables were analyzed using a descriptive analysis method (ie, proportions, means, medians. Paired samples t-tests or Wilcoxon matched-pair signed-rank tests were used to analyze the overall group differences between the pretest and posttest outcome measures where appropriate.Results: A total of 108 out of 115 (93.9% participants completed the posttest survey. The Physical Component Summary of the SF36v2 was the only measure that demonstrated significant improvement (P < 0.001.Conclusion: A spinal triage assessment program delivered by PTs can be viewed as a complex intervention that may have the potential to affect a wide range of patient-related outcomes. Further research is needed to examine the long-term outcomes and explore potential mechanisms of improvement using a biopsychosocial framework.Keywords: interprofessional practice, quality of life, back pain, orthopedics

  19. An action research study of secondary science assessment praxes (United States)

    Ryan, Thomas Gerald

    This practical participatory action research study illuminates the assessment praxes of four Ontario secondary level science teachers at one school using a facilitative approach. Participants were joined by a thematic concern, that is, a commitment to inform and improve assessment. Hence, two distinct sets of research questions emerged. The first involves the nature of assessment as we asked, what was the current state of assessment practice in secondary science? What were participants' initial understandings of assessment and actual practices at the onset of this research? To what extent did these initial understandings and actual practices change due to the illumination of assessment praxes through action research involvement? What was their level of awareness of current Ontario government pronouncements and in what ways did they implement this knowledge? The second theme, concerning the nature of action research, was realised by asking what did participants learn about action research? What other learning and professional gains were realised during this study? And, what did I learn about action research and assessment through my involvement in this study? Data were collected via supportive discussion groups, individual interviews, classroom visitations, journals and documentation. This professional development experience facilitated 'interactive professionalism' as teachers worked in a small group and interacted frequently in the course of planning, testing new ideas, attempting to solve different problems, and assess the effectiveness of those ideas. In addition, this action research effort was strategic and systematic, to attain a high degree of specific interactions, (personal interviews, group meetings, classroom observations, evidence collection). This series of deliberate and planned intentions helped participants solve assessment dilemmas. We developed an awareness and understanding of the need for more preservice and inservice assessment training

  20. Environmental risk assessment of ivermectin: A case study. (United States)

    Liebig, Markus; Fernandez, Alvaro Alonso; Blübaum-Gronau, Elke; Boxall, Alistair; Brinke, Marvin; Carbonell, Gregoria; Egeler, Philipp; Fenner, Kathrin; Fernandez, Carlos; Fink, Guido; Garric, Jeanne; Halling-Sørensen, Bent; Knacker, Thomas; Krogh, Kristine A; Küster, Anette; Löffler, Dirk; Cots, Miguel Angel Porcel; Pope, Louise; Prasse, Carsten; Römbke, Jörg; Rönnefahrt, Ines; Schneider, Manuel K; Schweitzer, Natascha; Tarazona, José V; Ternes, Thomas A; Traunspurger, Walter; Wehrhan, Anne; Duis, Karen


    The veterinary parasiticide ivermectin was selected as a case study compound within the project ERAPharm (Environmental Risk Assessment of Pharmaceuticals). Based on experimental data generated within ERAPharm and additional literature data, an environmental risk assessment (ERA) was performed mainly according to international and European guidelines. For the environmental compartments surface water, sediment, and dung, a risk was indicated at all levels of the tiered assessment approach. Only for soil was no risk indicated after the lower tier assessment. However, the use of effects data from additional 2-species and multispecies studies resulted in a risk indication for collembolans. Although previously performed ERAs for ivermectin revealed no concern for the aquatic compartment, and transient effects on dung-insect populations were not considered as relevant, the present ERA clearly demonstrates unacceptable risks for all investigated environmental compartments and hence suggests the necessity of reassessing ivermectin-containing products. Based on this case study, several gaps in the existing guidelines for ERA of pharmaceuticals were shown and improvements have been suggested. The action limit at the start of the ERA, for example, is not protective for substances such as ivermectin when used on intensively reared animals. Furthermore, initial predicted environmental concentrations (PECs) of ivermectin in soil were estimated to be lower than refined PECs, indicating that the currently used tiered approach for exposure assessment is not appropriate for substances with potential for accumulation in soil. In addition, guidance is lacking for the assessment of effects at higher tiers of the ERA, e.g., for field studies or a tiered effects assessment in the dung compartment.

  1. Juvenile idiopathic arthritis outcome and prognosis according to catamnesis evaluation

    Directory of Open Access Journals (Sweden)

    O V Semenova


    Full Text Available Objective. To study outcome and prognosis in pts with juvenile idiopathic arthritis (JIA. Material and methods. 239 JIA pts with disease duration of 10 years and more were analyzed. 80 children and adolescents before 18 years old (66 girls and 14 boys were included in group 1. Arthritis clinical and laboratory activity, radiological stage and functional status according to Steinbroker and CHAQ questionnaire were assessed. 159 grown up pts (109 female and 50 male suffering from JIA from childhood were included in group 2. They were examined using Stanford Health Assessment Questionnaire (HAQ and a specially developed social status questionnaire. Results. Half pts of group 1 had recurrence of the disease during examination but activity in most cases did not exceed stage I or 2 (54% and 31% respectively. Joint destructive changes were revealed in 50% of pts. 80% of pts had radiological signs of secondary osteoarthritis. Amyloidosis was revealed in 2 from 27 pts with systemic type of JIA. 68% of pts had 1 or 2 functional class. 1/3 of pts did not have functional limitations (CHAQ=0. 13% of pts had maximal disability with CHAQ ranging from 2,1 to 3,0 (pts with polyarticular and systemic types of JIA. Most grown up pts (59% considered their health as good. Substantial part of them worked or learned. 10 pts did not worked because of the disease (1,5%. 61% of pts did not have functional limitations (HAQ=0. 32% of pts were disabled. Most of them had 3 or 2 disability degree and had possibility to work. Conclusion. Substantial part of pts with longstanding JIA have stabilization of the disease or remission. Recurrent course of the disease was characterized by decrease of activity. Most children and grown ups with longstanding disease have relatively benign functional outcome. Pts with polyarticular and systemic types of JIA require especial attention because they have maximal risk of joint destruction with severe disability.

  2. Teaching, Learning, and Assessment Together: Reflective Assessments for Middle and High School English and Social Studies (United States)

    Ellis, Arthur K.; Evans, Laurynn


    This book offers easy-to-use classroom strategies for middle and high school English and Social Studies classrooms. They demonstrate how teaching, learning, and assessment are inseparable and seamless. Each strategy will engage your students in activity and reflection, consuming little class time, costing nothing, and uniting the three dimensions…

  3. Assessing Middle and High School Social Studies & English: Differentiating Formative Assessment (United States)

    Waterman, Sheryn Spencer


    For middle and high school teachers of social studies and English, this book is filled with examples of instructional strategies that address students' readiness levels, interests, and learning preferences. It shows teachers how to formatively assess their students by addressing differentiated learning targets. Included are detailed examples of…

  4. Comprehensive Adult Student Assessment Systems Braille Reading Assessment: An Exploratory Study (United States)

    Posey, Virginia K.; Henderson, Barbara W.


    Introduction: This exploratory study determined whether transcribing selected test items on an adult life and work skills reading test into braille could maintain the same approximate scale-score range and maintain fitness within the item response theory model as used by the Comprehensive Adult Student Assessment Systems (CASAS) for developing…

  5. MRI based volumetric assessment of knee cartilage after ACL-reconstruction, correlated with qualitative morphologic changes in the joint and with clinical outcome. Is there evidence for early posttraumatic degeneration?; MRT-basierte Knorpelvolumetrie nach Kreuzbandersatzplastik in Korrelation mit qualitativen Gelenkveraenderungen und dem klinischen Outcome. Gibt es Hinweise auf fruehzeitige posttraumatische degenerative Veraenderungen?

    Energy Technology Data Exchange (ETDEWEB)

    Arnoldi, A.P.; Weckbach, S.; Horng, A.; Reiser, M. [Ludwig-Maximilians-Univ. Muenchen (Germany). Dept. of Clinical Radiology; Nussbickel, C. [Klinikum Garmisch-Partenkirchen (Germany). Dept. of Internal Medicine; Noebauer, I. [Medizinische Universitaet Wien (Austria). Klinik fuer Radiodiagnostik; Zysk, S. [Orthopaedie Zentrum Groebenzell (Germany). Center of Orthopaedics; Glaser, C. [NYU Medical Center, New York, NY (United States). Dept. of Radiology


    Purpose: The purpose of this study was to analyze potential quantitative and qualitative changes of the knee cartilage and joint indicative of early posttraumatic OA 4 years after ACL-reconstruction and to correlate the MRI-findings with the clinical outcome (CO). Materials and Methods: 1.5 T MRI-scans were performed on 9 patients post-op and 4 years later. Using a high-resolution T 1-w-fs-FLASH-3D-sequence cartilage volume (cVol) and thickness (mTh) were quantified. Using standard PD-w fs and T 1-w sequences qualitative changes of the joint structures were analyzed based on the WORMS-score. CO was rated by an orthopaedic surgeon using Lysholm-score, OAK-score, Tegner-activity-score (TAS), and Arthrometer KT-1000 testing. Results: Mean changes of cVol were -1.8 % (range: -5.9 %; + 0.7 %) and of mTh -0.8 % (range: -3.0 %; + 1.1 %). No significant change (95 %-CI) could be identified for any compartment. Three patients developed new peripatellar ostheophytes, acute trauma related changes mostly decreased. Mean outcome of Lysholm-score and OAK-score were 90 pts and 86 pts, mean TAS was 4.3 pts. Average maximum tibial translation reached 5.2 mm comparing to 6.7 mm on the healthy contralateral side. Conclusion: Despite a tendency towards decreased cVol and mTh 4 years after ACL-reconstruction qMRI revealed no significant cartilage loss. Newly developing osteophytes did not match with the observed good CO. This small pilot study motivates future quantitative and qualitative-structural MRI-based assessment of articular cartilage and other joint structures in order to improve diagnostic tools for the detection of early OA. (orig.)

  6. Development of a Probabilistic Assessment Methodology for Evaluation of Carbon Dioxide Storage (United States)

    Burruss, Robert A.; Brennan, Sean T.; Freeman, P.A.; Merrill, Matthew D.; Ruppert, Leslie F.; Becker, Mark F.; Herkelrath, William N.; Kharaka, Yousif K.; Neuzil, Christopher E.; Swanson, Sharon M.; Cook, Troy A.; Klett, Timothy R.; Nelson, Philip H.; Schenk, Christopher J.


    This report describes a probabilistic assessment methodology developed by the U.S. Geological Survey (USGS) for evaluation of the resource potential for storage of carbon dioxide (CO2) in the subsurface of the United States as authorized by the Energy Independence and Security Act (Public Law 110-140, 2007). The methodology is based on USGS assessment methodologies for oil and gas resources created and refined over the last 30 years. The resource that is evaluated is the volume of pore space in the subsurface in the depth range of 3,000 to 13,000 feet that can be described within a geologically defined storage assessment unit consisting of a storage formation and an enclosing seal formation. Storage assessment units are divided into physical traps (PTs), which in most cases are oil and gas reservoirs, and the surrounding saline formation (SF), which encompasses the remainder of the storage formation. The storage resource is determined separately for these two types of storage. Monte Carlo simulation methods are used to calculate a distribution of the potential storage size for individual PTs and the SF. To estimate the aggregate storage resource of all PTs, a second Monte Carlo simulation step is used to sample the size and number of PTs. The probability of successful storage for individual PTs or the entire SF, defined in this methodology by the likelihood that the amount of CO2 stored will be greater than a prescribed minimum, is based on an estimate of the probability of containment using present-day geologic knowledge. The report concludes with a brief discussion of needed research data that could be used to refine assessment methodologies for CO2 sequestration.

  7. Regional issue identification and assessment: study methodology. First annual report

    Energy Technology Data Exchange (ETDEWEB)


    The overall assessment methodologies and models utilized for the first project under the Regional Issue Identification and Assessment (RIIA) program are described. Detailed descriptions are given of the methodologies used by lead laboratories for the quantification of the impacts of an energy scenario on one or more media (e.g., air, water, land, human and ecology), and by all laboratories to assess the regional impacts on all media. The research and assessments reflected in this document were performed by the following national laboratories: Argonne National Laboratory; Brookhaven National Laboratory; Lawrence Berkeley Laboratory; Los Alamos Scientific Laboratory; Oak Ridge National Laboratory; and Pacific Northwest Laboratory. This report contains five chapters. Chapter 1 briefly describes the overall study methodology and introduces the technical participants. Chapter 2 is a summary of the energy policy scenario selected for the RIIA I study and Chapter 3 describes how this scenario was translated into a county-level siting pattern of energy development. The fourth chapter is a detailed description of the individual methodologies used to quantify the environmental and socioeconomic impacts of the scenario while Chapter 5 describes how these impacts were translated into comprehensive regional assessments for each Federal Region.

  8. A Study of Sustainable Assessment Theory in Higher Education Tutorials (United States)

    Beck, Robert J.; Skinner, William F.; Schwabrow, Lynsey A.


    A study of sustainable assessment theory in nine tutorial courses at four colleges demonstrated that three long-term learning outcomes improved: Independence, Intellectual Maturity and Creativity. Eight of 10 traits associated with these outcomes were validated through internal reliability, faculty and student rubrics, and faculty case studies…

  9. Ecological Momentary Assessment (EMA) in Studies of Substance Use (United States)

    Shiffman, Saul


    Ecological momentary assessment (EMA) is particularly suitable for studying substance use, because use is episodic and thought to be related to mood and context. This article reviews EMA methods in substance use research, focusing on tobacco and alcohol use and relapse, where EMA has been most applied. Common EMA designs combine event-based…

  10. Literary Study, Measurement, and the Sublime: Disciplinary Assessment (United States)

    Heiland, Donna, Ed.; Rosenthal, Laura J., Ed.


    This collection of essays, "Literary Study, Measurement, and the Sublime: Disciplinary Assessment," edited by Donna Heiland and Laura J. Rosenthal, represents an important new venture in the Foundation's communication program. The book is the product of many authors, including the editors, both of whom have written essays for it. But it is the…

  11. Assessing the Flipped Classroom in Operations Management: A Pilot Study (United States)

    Prashar, Anupama


    The author delved into the results of a flipped classroom pilot conducted for an operations management course module. It assessed students' perception of a flipped learning environment after making them experience it in real time. The classroom environment was construed using a case research approach and students' perceptions were studied using…

  12. Studies on the risk assessment of Listeria monocytogenes

    NARCIS (Netherlands)

    Notermans, S.; Dufrenne, J.; Teunis, P.; Chackraborty, T.


    Humans are frequently exposed to Listeria monocytogenes, and high numbers may be ingested during consumption of certain types of food. However, epidemiological investigations show that listeriosis is a rare disease. Risk assessment studies using an animal mouse model indicate that almost all L. mono

  13. A Validation Study of the Student Oral Proficiency Assessment (SOPA). (United States)

    Thompson, Lynn E.; Kenyon, Dorry M.; Rhodes, Nancy C.

    This study validated the Student Oral Proficiency Assessment (SOPA), an oral proficiency instrument designed for students in elementary foreign language programs. Elementary students who were tested with the SOPA were also administered other instruments designed to measure proficiency. These instruments included the Stanford Foreign Language Oral…

  14. Safety assessment for hair-spray resins: risk assessment based on rodent inhalation studies. (United States)

    Carthew, Philip; Griffiths, Heather; Keech, Stephen; Hartop, Peter


    The methods involved in the safety assessment of resins used in hair-spray products have received little peer review, or debate in the published literature, despite their widespread use, in both hairdressing salons and the home. The safety assessment for these resins currently involves determining the type of lung pathology that can be caused in animal inhalation exposure studies, and establishing the no-observable-effect level (NOEL) for these pathologies. The likely human consumer exposure is determined by techniques that model the simulated exposure under "in use" conditions. From these values it is then possible to derive the likely safety factors for human exposure. An important part of this process would be to recognize the intrinsic differences between rodents and humans in terms of the respiratory doses that each species experiences during inhalation exposures, for the purpose of the safety assessment. Interspecies scaling factors become necessary when comparing the exposure doses experienced by rats, compared to humans, because of basic differences between species in lung clearance rates and the alveolar area in the lungs. The rodent inhalation data and modeled human exposure to Resin 6965, a resin polymer that is based on vinyl acetate, has been used to calculate the safety factor for human consumer exposure to this resin, under a range of "in use" exposure conditions. The use of this safety assessment process clearly demonstrates that Resin 6965 is acceptable for human consumer exposure under the conditions considered in this risk assessment.

  15. Exposure assessment in studies on health effects of traffic exhaust

    Energy Technology Data Exchange (ETDEWEB)

    Setaelae, S. [Association for the Pulmonary Disabled, Helsinki (Finland); Jaakkola, J.J.K. [Helsinki Univ. (Finland). Dept. of Public Health


    A main source of outdoor air pollution is road traffic, which produces a complex mixture of nitrogen oxides, carbon monoxide, volatile hydrocarbons, airborne particles and some other compounds. Traffic exhaust affects also the concentrations of ozone and other photo chemical oxidants. In earlier studies those components have had remarkable health effects. Several studies on occupational exposure to automobile exhaust have been published and several studies have been observed an association between both outdoor and indoor pollutant levels and health outcomes. However, there are only a few epidemiological studies in which traffic exhaust, a complex mixture, has been studied in its entirety. During recent years, interesting epidemiological studies of the health effects of this complex mixture have been published. Human exposure assessment for traffic exhaust can be categorized according to the environment of exposure (indoors, outdoors, in-traffic) or to the method of exposure assessment (direct or indirect methods). In this presentation the methods are further categorized into (1) traffic activity, (2) air concentration measurements, and (3) dispersion models, in order to better understand the advantages and disadvantages of different approaches. The objective of this presentation is to make a critical review of exposure assessments in the epidemiological studies on health effects of traffic exhaust. (author)

  16. Efficacy and safety of nimesulide long term administration in patients with osteoarthritis: results of 12-months open controlled study DINAMO (long term administration of nimesulide in osteoarthritis multifactor assessment

    Directory of Open Access Journals (Sweden)

    L I Alexeeva


    Full Text Available Objective. To compare efficacy and safety of nimesulide and paracetamol in treatment of patients with osteoarthritis (OA during 12 months. Material and methods. 40 women (mean age 66,8±5,1 years with knee osteoarthritis (II-III stage according to Kellgren-Lawrence having intensive pain (>40 mm on VAS were included. Group 1 pts (n=20 received nimesulide 200-100 mg/day. Group 2 pts were treated with paracetamol till 3 g/day. WOMAC was used as efficacy measure. Safety was assessed with endoscopic examination of upper gastrointestinal tract, ECG, blood pressure and ECG Holter monitoring, clinical and biochemical blood parameters. Statistical significance of differences was assessed with Student’s t-test, χ2 and Fisher exact test Results. WOMAC index decreased during treatment from 1182,7±345,9 to 698,4±351,1 for nimesulide and from 1136,4±313,8 to 1031,6±21 for paracetamol (p<0,05. There were 6 cases of gastrointestinal complications and 4 cases of hypertension development or deterioration in each group. Coronary heart disease developed or deteriorated in 4 patients receiving nimesulide but not in control group. Liver function tests did not deteriorated during treatment with nimesulide. Conclusion. Nimesulide was more effective than paracetamol in treatment of OA. But risk of cardiovascular complications development during treatment with NSAIDs requires serious attention. Nimesulide did not induced liver damage during long term treatment.

  17. Self-assessment and students’ study strategies in a community of clinical practice: A qualitative study

    Directory of Open Access Journals (Sweden)

    Hanan M. Al-Kadri


    Full Text Available : Self-assessment is recognized as a necessary skill for lifelong learning. It is widely reported to offer numerous advantages to the learner. The research evaluated the impact of students’ and supervisors’ self-assessment and feedback training on students’ perceptions and practices of self-assessment. Moreover, it evaluated the effect of self-assessment process on students’ study strategies within a community of clinical practice.: We conducted a qualitative phenomenological study from May 2008 to December 2009. We held 37 semi-structured individual interviews with three different cohorts of undergraduate medical students until we reached data saturation. The cohorts were exposed to different contexts while experiencing their clinical years’ assessment program. In the interviews, students’ perceptions and interpretations of ‘self-assessment practice’ and ‘supervisor-provided feedback’ within different contexts and the resulting study strategies were explored.: The analysis of interview data with the three cohorts of students yielded three major themes: strategic practice of self-assessment, self-assessment and study strategies, and feedback and study strategies. It appears that self-assessment is not appropriate within a summative context, and its implementation requires cultural preparation. Despite education and orientation on the two major components of the self-assessment process, feedback was more effective in enhancing deeper study strategies.: This research suggests that the theoretical advantages linked to the self-assessment process are a result of its feedback component rather than the practice of self-assessment isolated from feedback. Further research exploring the effects of different contextual and personal factors on students’ self-assessment is needed.

  18. Development Impact Assessment (DIA) Case Study. South Africa

    Energy Technology Data Exchange (ETDEWEB)

    Cox, Sadie [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nawaz, Kathleen [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Sandor, Debra [National Renewable Energy Laboratory (NREL), Golden, CO (United States)


    This case study reviews South Africa’s experience in considering the impacts of climate change action on development goals, focusing on the South African energy sector and development impact assessments (DIAs) that have and could be used to influence energy policy or inform the selection of energy activities. It includes a review of assessments—conducted by government ministries, technical partners, and academic institutes and non-governmental organizations (NGOs)—that consider employment, health, and water implications of possible energy sector actions, as well as multi-criteria impact assessments.

  19. Instruments for the assessment of social anxiety disorder: Validation studies. (United States)

    Osório, Flávia de Lima; Crippa, José Alexandre de Souza; Loureiro, Sonia Regina


    Great progress has been observed in the literature over the last decade regarding the validation of instruments for the assessment of Social Anxiety Disorder in the Brazilian context. Particularly outstanding in this respect is the production of a group of Brazilian investigators regarding the psychometric study of the following instruments: Liebowitz Social Anxiety Scale, Social Phobia Inventory, Brief Social Phobia Scale, Disability Profile, Liebowitz Self-Rated Disability Scale, Social Phobia Safety Behaviors Scale and Self-Statements During Public Speaking Scale, which have proved to be appropriate and valid for use in the adult Brazilian population, representing resources for the assessment of social anxiety in clinical and experimental situations.

  20. A Longitudinal Study of the Bidirectional Relationship Between Social Support and Posttraumatic Stress Following a Natural Disaster. (United States)

    Platt, Jonathan M; Lowe, Sarah R; Galea, Sandro; Norris, Fran H; Koenen, Karestan C


    There is ample evidence that social support is protective against posttraumatic stress (PTS) symptoms through social causation processes. It is also likely that PTS is associated with decreased social support through social selection processes. Few studies, however, have examined the longitudinal and bidirectional associations between social support and PTS in a postdisaster context, and whether such associations vary by type of support (e.g., emotional, informational, or tangible). We examined these relationships using Galveston Bay Recovery Study data. Participants (N = 658) were interviewed 2-6 months (W1), 5-9 months (W2), and 14-19 months (W3) after Hurricane Ike in 2008. Longitudinal relationships between each support type and PTS were examined in cross-lagged models. W1 emotional support was negatively associated with W2 PTS (Estimate = -.13, p = .007), consistent with social causation. W1 PTS was negatively associated with W2 emotional support (Estimate = -.14, p = .019), consistent with social selection. In contrast, pathways were nonsignificant at subsequent waves and for informational and tangible support. Results suggested that postdisaster social causation and selection were limited to emotional support and diminish over time. Based on these findings, postdisaster services should emphasize restoring supportive social connections to minimize the psychiatric consequences of disaster, especially among those with prior evidence of distress.

  1. "Assessment of different bioequivalent metrics in Rifampin bioequivalence study "


    "Rouini MR; Tajer Zadeh H; Valad Khani M "


    The use of secondary metrics has become special interest in bioequivalency studies. The applicability of partial area method, truncated AUC and Cmax/AUC has been argued by many authors. This study aims to evaluate the possible superiority of these metrics to primary metrics (i.e. AUCinf, Cmax and Tmax). The suitability of truncated AUC for assessment of absorption extent as well as Cmax/AUC and partial AUC for the evaluation of absorption rate in bioequivalency determination was investigated ...

  2. Nai Kun wind farm environmental impact assessment study design

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, S.; Shum, M.; Embley, E. [Pottinger Gaherty Environmental Consultants Ltd., Vancouver, BC (Canada)


    Uniterre Resources Ltd., ABB New Ventures and ABB Inc. propose the Nai Kun Wind Farm project, and the firm Pottinger Gaherty Environmental Consultants LTD. (PGL) was commissioned to conduct an environmental impact assessment for the project. A description of the studies considered as a requirement for the environmental impacts assessment of the project is included in this draft report. Before proceeding with the detailed studies, it was decided to present this draft report to the stakeholders and regulatory authorities to obtain feedback and a review. Nowadays in electricity markets, wind energy is becoming a differentiated and highly valued product. The Nai Kun Wind Farm project, as proposed, would entail the development, construction and operation of a 700 megawatt (MW) wind generation facility located off the northeast coast of Graham Island (Haida Gwaii) in Hecate Strait in British Columbia. It is expected that the project will generate greenhouse gas emission reduction credits. The information about the site and the project, as was known on May 24, 2002, was used for the preparation of this draft report. The present document includes an introduction in Chapter 1, followed by background information in Chapter 2. The Environmental impact assessment framework was reviewed in Chapter 3, and the public consultation plan was described in Chapter 4. The environmental impact assessment designs are discussed in Chapter 5 and a schedule for environmental studies provided in Chapter 6. The next steps are detailed in Chapter 7 of the document. 10 refs., tabs., 1 fig.

  3. Study Progress and Trends of Strategic Environmental Assessment in China

    Institute of Scientific and Technical Information of China (English)

    Cai Chunmiao; Shang Jincheng


    Strategic environmental assessment (SEA) in China has developed rapidly since it was introduced into China in the 1990s.Chinese government promulgated the Environmental Impact As-sessment Law of China (hereinafter referred to as the EIA Law) in 2002.In this law, it is stipulated clearly that regional and sector plans should be assessed.Through investigating materials and ana-lyzing literatures, this article analyses the practical and academic study achievements of SEA in China that have been achieved since the EIA Law was implemented, probes into the current situation of the main level of SEA in China--plan EIA, then summarizes the development characteristics, and eventually, puts forward the development trends of SEA in China.The research conclusions can offer the foundations for comprehending systematically the progress of SEA in China.

  4. Report of the Study Group on Assessment and Evaluation

    CERN Document Server

    Crouch, R; Netter, K; Crouch, Richard; Gaizuaskas, Robert; Netter, Klaus


    This is an interim report discussing possible guidelines for the assessment and evaluation of projects developing speech and language systems. It was prepared at the request of the European Commission DG XIII by an ad hoc study group, and is now being made available in the form in which it was submitted to the Commission. However, the report is not an official European Commission document, and does not reflect European Commission policy, official or otherwise. After a discussion of terminology, the report focusses on combining user-centred and technology-centred assessment, and on how meaningful comparisons can be made of a variety of systems performing different tasks for different domains. The report outlines the kind of infra-structure that might be required to support comparative assessment and evaluation of heterogenous projects, and also the results of a questionnaire concerning different approaches to evaluation.

  5. Environmental impact assessment as a complement of life cycle assessment. Case study: Upgrading of biogas. (United States)

    Morero, Betzabet; Rodriguez, María B; Campanella, Enrique A


    This work presents a comparison between an environmental impact assessment (EIA) and a life cycle assessment (LCA) using a case study: upgrading of biogas. The upgrading of biogas is studied using three solvents: water, physical solvent and amine. The EIA follows the requirements of the legislation of Santa Fe Province (Argentina), and the LCA follows ISO 14040. The LCA results showed that water produces a minor impact in most of the considered categories whereas the high impact in the process with amines is the result of its high energy consumptions. The positive results obtained in the EIA (mainly associated with the cultural and socioeconomic components) make the project feasible and all the negative impacts can be mitigated by preventive and remedial measures. From the strengths and weaknesses of each tool, it is inferred that the EIA is a procedure that can complement the LCA.

  6. 一种低复杂度降低FBMC-OQAM峰均值比的PTS双层搜索算法%A Low Complexity PTS Algorithm with Dual Layered Phase Sequencing to Reduce PAPR of the FBMC-OQAM Signal

    Institute of Scientific and Technical Information of China (English)

    吴垒; 谢显中; 张苗; 雷维嘉



  7. Assessment of Confounding in Studies of Delay and Survival

    DEFF Research Database (Denmark)

    Tørring, Marie Louise; Vedsted, Peter; Frydenberg, Morten

    of the influence of delay on survival have been subject to great uncertainties due to unmeasured confounding and measurement error. Systematic evaluation of confounding is needed. AIM: The purpose of this project is to assess confounding in studies of delay and survival in breast cancer patients. We aim to: 1......) Clarify which factors are considered confounders or intermediate variables in the literature. 2) Assess how and to what extent these factors bias survival estimates. CONSIDERATIONS: As illustrated in Figure 1, symptoms of cancer may alert patients, GP's, and hospital doctors differently and influence both...... delay and survival time in different ways. We therefore assume that the impact of confounding factors depends on the type of delay studied (e.g., patient delay, GP delay, referral delay, or treatment delay). MATERIALS & METHODS: The project includes systematic review and methodological developments...

  8. A study on safety assessment methodology for a vitrification plant

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Y. C.; Lee, G. S.; Choi, Y. C.; Kim, G. H. [Yonsei Univ., Seoul (Korea, Republic of)


    In this study, the technical and regulatory status of radioactive waste vitrification technologies in foreign and domestic plants is investigated and analyzed, and then significant factors are suggested which must be contained in the final technical guideline or standard for the safety assessment of vitrification plants. Also, the methods to estimate the stability of vitrified waste forms are suggested with property analysis of them. The contents and scope of the study are summarized as follows : survey of the status on radioactive waste vitrification technologies in foreign and domestic plants, survey of the characterization methodology for radioactive waste form, analysis of stability for vitrified waste forms, survey and analysis of technical standards and regulations concerned with them in foreign and domestic plants, suggestion of significant factors for the safety assessment of vitrification plants, submission of regulated technical standard on radioactive waste vitrification plats.

  9. Feasibility studies for assessing internal exposure to {sup 233}U

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, D.J.; Sharma, R.C.; Ramanujam, A.; Haridasan, T.K.; Sawant, P.D.; Rathinam, M


    The potential internal occupational exposure encountered as a consequence of the {sup 232}Th-{sup 233}U fuel cycle are likely to arise predominantly from the inhalation of {sup 232}Th, {sup 233}U and ({sup 232}Th + {sup 233}U) compounds of absorption Types M and S. In the past, although direct and indirect methods for assessments of internal exposure to {sup 232}Th and its daughters were developed, standardised and employed, no such attempts have been made with regard to {sup 233}U and {sup 233}U+{sup 232}Th. Therefore, feasibility studies for assessing internal exposures to {sup 233}U have been conducted using three methods: urine bioassay, in vivo counting and measurement of thoron gas in the exhaled breath of a worker. This paper describes details of these studies and discusses the results obtained. (author)

  10. Thorium assessment study quarterly progress report, third quarter fiscal 1977

    Energy Technology Data Exchange (ETDEWEB)

    Spiewak, I.; Bartine, D. E.; Burns, T. J.; Cleveland, J. C.; Thomas, W. E.; White, J. R.


    The objective of the program described is to contribute to the ongoing assessment of the potential role of thorium fuel cycles for alleviating safeguards concerns. Scenarios include (1) no fuel recycle permitted, (2) fuel recycle permitted only in secure regions (''energy parks'') with denatured (chemically non-separable) fuels only outside these regions, and (3) no limits on fuel recycle. A further objective is to provide nuclear mass balance data on HTGRs required by ERDA contractors for comparative cost-benefit studies.

  11. Explosion approach for external safety assessment: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D. Michael; Halford, Ann [Germanischer Lloyd, Loughborough (United Kingdom); Mendes, Renato F. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)


    Several questions related to the potential for explosions are explored as this became an important subject during an enterprise risk analysis. The understanding of explosions underwent a substantial evolution in the final 20 years of the 20{sup th} century following international research projects in Europe involving several research institutes, as well gas and oil companies. This led to the development of techniques that could be used to assess the potential consequences of explosions on oil, gas and petrochemical facilities. This paper presents an overview of the potential for explosions in communities close to industrial sites or pipelines right of way (RoW), where the standard explosion assessment methods cannot be applied. With reference to experimental studies, the potential for confined explosions in buildings and Vapor Cloud Explosions is explored. Vapor Cloud Explosion incidents in rural or urban areas are also discussed. The method used for incorporating possible explosion and fire events in risk studies is also described using a case study. Standard explosion assessment methodologies and a revised approach are compared as part of an on going evaluation of risk (author)

  12. Assessment of apical periodontitis by MRI. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Geibel, M.A. [Ulm Univ. (Germany). Oral and Maxillofacial Surgery; Schreiber, E.S.; Bracher, A.K.; Rasche, V. [Ulm Univ. (Germany). Internal Medicine II; Hell, E.; Ulrici, J. [Sirona Dental Systems GmbH, Bensheim (Germany). Dental Imaging; Sailer, L.K. [DOC Praxisklinik im Wiley, Neu-Ulm (Germany). MKG; Ozpeynirci, Y. [Ulm Univ. (Germany). Diagnostic and Interventional Radiology


    The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility study. Periapical lesions were defined as periapical radiolucencies (CBCT) or structural changes in the spongy bone signal (MRI), which were connected with the apical part of a root and with at least twice the width of the periodontal ligament space. The location and dimension of the lesions were compared between MRI and CBCT. While mainly mineralized tissue components such as teeth and bone were visible with CBCT, complimentary information of the soft tissue components was assessable with MRI. The MRI images provided sufficient diagnostic detail for the assessment of the main structures of interest. Heterogeneous contrast was observed within the lesion, with often a clear enhancement close to the apical foramen and the periodontal gap. No difference for lesion visibility was observed between MRI and CBCT. The lesion dimensions corresponded well, but were slightly but significantly overestimated with MRI. A heterogeneous lesion appearance was observed in several patients. Four patients presented with a well circumscribed hyperintense signal in the vicinity of the apical foramen. The MRI capability of soft tissue characterization may facilitate detailed analysis of periapical lesions. This clinical study confirms the applicability of multi-contrast MRI for the identification of periapical lesions.

  13. Development of a Burn Escharotomy Assessment Tool: A Pilot Study. (United States)

    Ur, Rebecca; Holmes, James H; Johnson, James E; Molnar, Joseph A; Carter, Jeffrey E


    Severe burn injuries can require escharotomies which are urgent, infrequent, and relatively high-risk procedures necessary to preserve limb perfusion and sometimes ventilation. The American Burn Association Advanced Burn Life Support© course educates surgeons and emergency providers about escharotomy incisions but lacks a biomimetic trainer to demonstrate, practice, or provide assessment. The goal was to build an affordable biomimetic trainer with discrete points of failure and pilot a validation study. Fellowship-trained burn and plastic surgeons worked with special effect artists and anatomists to develop a biomimetic trainer with three discrete points of failure: median or ulnar nerve injury, fasciotomy, and failure to check distal pulse. Participants were divided between experienced and inexperienced, survey pre- and post-procedure on a biomimetic model while being timed. The trainer total cost per participant was less than $35. Eighteen participants were involved in the study. The inexperienced (0-1 prior escharotomies performed) had significantly more violations at the discrete points of failure relative to more experienced participants (P = .036). Face validity was assessed with 100% of participants agreement that the model appeared similar to real life and was valuable in their training. Given the advancements in biomimetic models and the need to train surgeons in how to perform infrequent, emergent surgical procedures, an escharotomy trainer is needed today. The authors developed an affordable model with a successful pilot study demonstrating discrimination between experienced and inexperienced surgeons. Additional research is needed to increase the reliability and assessment metrics.

  14. Offshore risk assessment principles, modelling and applications of QRA studies

    CERN Document Server

    Vinnem, Jan-Erik


    attempt has been made to capture the new trends in the regulations, to the extent they are known. There have over the last 10-15 years been published a few textbooks on risk assessment, most of them are devoted to relatively generic topics. Some are also focused on the risk management aspects, in general and with offshore applicability. None are known to address the needs and topics of the use of QRA studies by the offshore industry in particular. The present work is trying to bridge this gap. The use of QRA studies is somewhat special in Northern Europe, and par- cularly in Norway. The use of

  15. Probabilistic Tsunami Hazard Assessment: the Seaside, Oregon Pilot Study (United States)

    Gonzalez, F. I.; Geist, E. L.; Synolakis, C.; Titov, V. V.


    A pilot study of Seaside, Oregon is underway, to develop methodologies for probabilistic tsunami hazard assessments that can be incorporated into Flood Insurance Rate Maps (FIRMs) developed by FEMA's National Flood Insurance Program (NFIP). Current NFIP guidelines for tsunami hazard assessment rely on the science, technology and methodologies developed in the 1970s; although generally regarded as groundbreaking and state-of-the-art for its time, this approach is now superseded by modern methods that reflect substantial advances in tsunami research achieved in the last two decades. In particular, post-1990 technical advances include: improvements in tsunami source specification; improved tsunami inundation models; better computational grids by virtue of improved bathymetric and topographic databases; a larger database of long-term paleoseismic and paleotsunami records and short-term, historical earthquake and tsunami records that can be exploited to develop improved probabilistic methodologies; better understanding of earthquake recurrence and probability models. The NOAA-led U.S. National Tsunami Hazard Mitigation Program (NTHMP), in partnership with FEMA, USGS, NSF and Emergency Management and Geotechnical agencies of the five Pacific States, incorporates these advances into site-specific tsunami hazard assessments for coastal communities in Alaska, California, Hawaii, Oregon and Washington. NTHMP hazard assessment efforts currently focus on developing deterministic, "credible worst-case" scenarios that provide valuable guidance for hazard mitigation and emergency management. The NFIP focus, on the other hand, is on actuarial needs that require probabilistic hazard assessments such as those that characterize 100- and 500-year flooding events. There are clearly overlaps in NFIP and NTHMP objectives. NTHMP worst-case scenario assessments that include an estimated probability of occurrence could benefit the NFIP; NFIP probabilistic assessments of 100- and 500-yr

  16. Situated argumentation, learning and science education: A case study of prospective teachers' experiences in an innovative science course (United States)

    Munford, Danusa

    Various authors had called attention to the significance of argumentation to science education. Nevertheless, argumentation practices had been considerably rare in science classrooms. Moreover, little is know about how people engage in argumentation as science learners to construct knowledge about the natural world and about science. This study was conducted in a science education course for prospective teachers (PTs) at a university in the Northeast United States. The course was composed of three instructional units, focusing on evolution, light and climate change. In each unity, PTs were confronted with questions, and, working in pairs, they built evidence-based arguments. Various types of technology tools were used to support PTs' in that process. The study addresses the experiences of four prospective teachers, adopting a case study research design informed by grounded theory and phenomenology theoretical frameworks. The research questions were: (1) What is the nature of the arguments that PTs' construct? (2) How PTs's understandings about argumentation develop throughout the course? (3) What accounts for PTs' understandings about argument construction? The primary sources of data for the study were (1) electronic artifacts constructed by PTs and (2) interviews with participants conducted after each unit. The structure of their arguments was analyzed to determine the extent to which PTs explored multiple explanations, provided relevant evidence to support their conclusions, explained how evidence and conclusions were related, and recognized limitations in explanations. The results of the study suggest that there are some common trends in the development of understandings about scientific arguments. Initially, learners acknowledged the role of evidence in scientific arguments, and tended to provide evidence to support their claims. However, PTs tended not to explain how these pieces of evidence would be related to their conclusions, and saw little value in

  17. Assessing analytical comparability of biosimilars: GCSF as a case study. (United States)

    Nupur, Neh; Singh, Sumit Kumar; Narula, Gunjan; Rathore, Anurag S


    The biosimilar industry is witnessing an unprecedented growth with the newer therapeutics increasing in complexity over time. A key step towards development of a biosimilar is to establish analytical comparability with the innovator product, which would otherwise affect the safety/efficacy profile of the product. Choosing appropriate analytical tools that can fulfil this objective by qualitatively and/or quantitatively assessing the critical quality attributes (CQAs) of the product is highly critical for establishing equivalence. These CQAs cover the primary and higher order structures of the product, product related variants and impurities, as well as process related impurities, and host cell related impurities. In the present work, we use such an analytical platform for assessing comparability of five approved Granulocyte Colony Stimulating Factor (GCSF) biosimilars (Emgrast, Lupifil, Colstim, Neukine and Grafeel) to the innovator product, Neupogen(®). The comparability studies involve assessing structural homogeneity, identity, secondary structure, and product related modifications. Physicochemical analytical tools include peptide mapping with mass determination, circular dichroism (CD) spectroscopy, reverse phase chromatography (RPC) and size exclusion chromatography (SEC) have been used in this exercise. Bioactivity assessment include comparison of relative potency through in vitro cell proliferation assays. The results from extensive analytical examination offer robust evidence of structural and biological similarity of the products under consideration with the pertinent innovator product. For the most part, the biosimilar drugs were found to be comparable to the innovator drug anomaly that was identified was that three of the biosimilars had a typical variant which was reported as an oxidized species in the literature. But, upon further investigation using RPC-FLD and ESI-MS we found that this is likely a conformational variant of the biotherapeutic been

  18. Joint irrigation districts hydropower assessment study. Final feasibility assessment report. Volume I

    Energy Technology Data Exchange (ETDEWEB)



    In August 1978, the United States Department of Energy and the Turlock Irrigation District entered into a cooperative agreement for a Joint District's Low-Head Hydropower Assessment Study. The purpose of the agreement was to carry out a study of the hydropower potential at sites within the borders of the Turlock, Merced, South San Joaquin, and Oakdale Irrigation Districts in California. The required data were gathered and analyzed. The results of this study indicate the total potential small hydropower capacity with the Joint Districts is 19,560 kW installed with an annual energy generation of 68,561,800 kWh. This is equivalent to oil-savings of 118,616 barrels per y.

  19. Final Technical Report: Renewable Energy Feasibility Study and Resources Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rivero, Mariah [BEC Environmental, Inc., Las Vegas, NV (United States)


    In March 2011, the U.S. Department of Energy (DOE) awarded White Pine County, Nevada, a grant to assess the feasibility of renewable resource-related economic development activities in the area. The grant project included a public outreach and training component and was to include a demonstration project; however, the demonstration project was not completed due to lack of identification of an entity willing to locate a project in White Pine County. White Pine County completed the assessment of renewable resources and a feasibility study on the potential for a renewable energy-focused economic sector within the County. The feasibility study concluded "all resources studied were present and in sufficient quantity and quality to warrant consideration for development" and there were varying degrees of potential economic impact based on the resource type and project size. The feasibility study and its components were to be used as tools to attract potential developers and other business ventures to the local market. White Pine County also marketed the County’s resources to the renewable energy business community in an effort to develop contracts for demonstration projects. The County also worked to develop partnerships with local educational institutions, including the White Pine County School District, conducted outreach and training for the local community.

  20. Consensus statement on assessment of waterpipe smoking in epidemiological studies. (United States)

    Maziak, Wasim; Ben Taleb, Ziyad; Jawad, Mohammed; Afifi, Rima; Nakkash, Rima; Akl, Elie A; Ward, Kenneth D; Salloum, Ramzi G; Barnett, Tracey E; Primack, Brian A; Sherman, Scott; Cobb, Caroline O; Sutfin, Erin L; Eissenberg, Thomas


    Numerous epidemiological accounts suggest that waterpipe smoking (aka hookah, shisha, narghile) has become a global phenomenon, especially among youth. The alarming spread of waterpipe and accumulating evidence of its addictive and harmful effects represent a new threat in the global fight to limit tobacco-related morbidity and mortality. In response to waterpipe's alarming trends, major public health and tobacco control organisations have started or are considering systematic collection of data about waterpipe smoking to monitor its trends and assess its harmful effects in different societies. Such plans require coordination and agreement on epidemiological measurement tools that reflect the uniqueness of this tobacco use method, and at the same time allow comparison of waterpipe trends across time and place, and with other tobacco use methods. We started a decade ago our work to develop standardised measures and definitions for the assessment of waterpipe smoking in epidemiological studies. In this communication, we try to expand and update these assessment tools in light of our increased knowledge and understanding of waterpipe use patterns, its context and marketing, as well as the need for evidence-guided policies and regulations to curb its spread. We have assembled for this purpose a group of leading waterpipe researchers worldwide, and worked through an iterative process to develop the suggested instruments and definitions based on what we know currently about the waterpipe epidemic. While the suggested measures are by no means comprehensive, we hope that they can provide the building blocks for standard and comparable surveillance of waterpipe smoking globally.

  1. Pain assessment in animal models: do we need further studies? (United States)

    Gigliuto, Carmelo; De Gregori, Manuela; Malafoglia, Valentina; Raffaeli, William; Compagnone, Christian; Visai, Livia; Petrini, Paola; Avanzini, Maria Antonietta; Muscoli, Carolina; Viganò, Jacopo; Calabrese, Francesco; Dominioni, Tommaso; Allegri, Massimo; Cobianchi, Lorenzo


    In the last two decades, animal models have become important tools in understanding and treating pain, and in predicting analgesic efficacy. Although rodent models retain a dominant role in the study of pain mechanisms, large animal models may predict human biology and pharmacology in certain pain conditions more accurately. Taking into consideration the anatomical and physiological characteristics common to man and pigs (median body size, digestive apparatus, number, size, distribution and communication of vessels in dermal skin, epidermal–dermal junctions, the immunoreactivity of peptide nerve fibers, distribution of nociceptive and non-nociceptive fiber classes, and changes in axonal excitability), swines seem to provide the most suitable animal model for pain assessment. Locomotor function, clinical signs, and measurements (respiratory rate, heart rate, blood pressure, temperature, electromyography), behavior (bright/quiet, alert, responsive, depressed, unresponsive), plasma concentration of substance P and cortisol, vocalization, lameness, and axon reflex vasodilatation by laser Doppler imaging have been used to assess pain, but none of these evaluations have proved entirely satisfactory. It is necessary to identify new methods for evaluating pain in large animals (particularly pigs), because of their similarities to humans. This could lead to improved assessment of pain and improved analgesic treatment for both humans and laboratory animals. PMID:24855386

  2. Daily living pain assessment in children with autism: Exploratory study. (United States)

    Dubois, A; Michelon, C; Rattaz, C; Zabalia, M; Baghdadli, A


    This study aims to broaden knowledge about pain expression and assessment in daily life situations in children with Autism Spectrum Disorder (ASD). The goals are to provide a description of the responses of the GED-DI, the French version of the NCCPC, and to test the internal structure validity of this scale. Thirty five children with ASD were included in this study (mean age=58months; mean developmental age=32months). The French version of the NCCPC was filled in by parents. Descriptive analysis of responses shows that children with ASD express pain through varied and common behaviours, related to different expressive markers (vocal, facial, activity, etc.). Behaviours more specific to the symptomology and disturbances of ASD are also displayed. A four-factor solution (negative emotional reaction, idiosyncratic expression, hyper-vigilance reaction, pain expression) emerges from an exploratory factor analysis that explains 54.4% of the total variance. Correlation coefficients show good psychometric qualities in terms of internal consistency, factorial validity and discriminant validity. This study provides new data about pain expression in daily life situations and shows that the French version of NCCPC adjusted to ASD children is relevant to assess pain in daily life situations.

  3. Assessing interpersonal aspects of schizoid personality disorder: preliminary validation studies. (United States)

    Kosson, David S; Blackburn, Ronald; Byrnes, Katherine A; Park, Sohee; Logan, Caroline; Donnelly, John P


    In 2 studies, we examined the reliability and validity of an interpersonal measure of schizoid personality disorder (SZPD) based on nonverbal behaviors and interpersonal interactions occurring during interviews. A total of 556 male jail inmates in the United States participated in Study 1; 175 mentally disordered offenders in maximum security hospitals in the United Kingdom participated in Study 2. Across both samples, scores on the Interpersonal Measure of Schizoid Personality Disorder (IM-SZ) exhibited adequate reliability and patterns of correlations with other measures consistent with expectations. The scale displayed patterns of relatively specific correlations with interview and self-report measures of SZPD. In addition, the IM-SZ correlated in an expected manner with features of psychopathy and antisocial personality and with independent ratings of interpersonal behavior. We address implications for assessment of personality disorder.

  4. Study on Spectral Fatigue Assessment of Trimaran Structure

    Directory of Open Access Journals (Sweden)

    Ren Huilong


    Full Text Available This study presents fatigue strength assessment of the trimaran platform by the spectral approach. Spectral fatigue calculations are based on complex stress transfer functions established through direct wave load analysis combined with stress response analysis. In this study, ANSYS software with 3 dimensional linear sea-keeping code AQWA is used to compute frequency response functions of the vessel at zero forward speed. Finite element analysis of global trimaran structure is performed in ANSYS software utilizing hydrodynamic wave loads. Hot spot stress approach is used to compute stress transfer functions of the selected critical details. A MATLAB program, based on direct calculation procedure of spectral fatigue is developed to calculate total fatigue damage using wave scatter data of North Atlantic. Damage incurred during individual heading direction is also calculated and presented by means of polar diagrams to study its contribution towards cumulative fatigue damage.

  5. Life cycle assessment study of a Chinese desktop personal computer. (United States)

    Duan, Huabo; Eugster, Martin; Hischier, Roland; Streicher-Porte, Martin; Li, Jinhui


    Associated with the tremendous prosperity in world electronic information and telecommunication industry, there continues to be an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of electronic and electric products (e-products). China's importance as both a consumer and supplier of e-products has grown at an unprecedented pace in recent decade. Hence, this paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese e-products from a global level. A desktop personal computer system has been selected to carry out a detailed and modular LCA which follows the ISO 14040 series. The LCA is constructed by SimaPro software version 7.0 and expressed with the Eco-indicator'99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the so-called CML method is used in order to estimate the influence of the choice of the assessment method on the result. Life cycle inventory information is complied by ecoinvent 1.3 databases, combined with literature and field investigations on the present Chinese situation. The established LCA study shows that that the manufacturing and the use of such devices are of the highest environmental importance. In the manufacturing of such devices, the integrated circuits (ICs) and the Liquid Crystal Display (LCD) are those parts contributing most to the impact. As no other aspects are taken into account during the use phase, the impact is due to the way how the electricity is produced. The final process steps--i.e. the end of life phase--lead to a clear environmental benefit if a formal and modern, up-to-date technical system is assumed, like here in this study.

  6. A Study of Chinese Commercial Banks’ Credit Risk Assessment

    Directory of Open Access Journals (Sweden)

    Xiaosong Zheng


    Full Text Available It has been a long time that Chinese small and medium-sized enterprises (SMEs have difficulties in dealing with financial problems. As a result of the imperfect financial environment in China, SMEs cannot find the effective way to obtain the funding, especially from Chinese commercial banks. In practice, the existing credit risk assessment and management policies cannot adapt to the requirements of SMEs, which means that developing new mechanisms and management policies is necessary. Based on the previous studies and the economic realities, this paper analyzes the credit status of commercial banks and sorts out the complex background to make a valuable conclusion. In the section of credit risk assessment mechanisms for SMEs, the author compares three classical models and introduces a parameter selection method which measures the financial and non-financial factors together. Besides the theoretical section, a case of Agricultural Bank of China will be studied and the paper will focus on the credit rating system and explore the innovative service for SMEs.

  7. assessing contributions of jgofs; previewing Studies in Ocean Ecology, Biogeochemistry (United States)

    Steinberg, Deborah K.; Ducklow, Hugh W.; Buesseler, Ken O.; Bowles, Margaret C.

    Despite impediments to travel imposed by global political and health concerns, 332 scientists and students from 32 countries gathered in Washington, D.C. in early May to celebrate the conclusion of the Joint Global Ocean Flux Study (JGOFS), and to assess both its accomplishments and the future course of research in ocean ecology and biogeochemistry.Launched in 1987 under the auspices of the Scientific Committee on Oceanic Research (SCOR), JGOFS became the first core project of the International Geosphere-Biosphere Programme (IGBP) 2 years later as its first field studies were getting underway. Global in scope and multinational and interdisciplinary from its inception, JGOFS adopted two major goals: to understand the processes controlling the cycling of carbon and other biogenic elements in the ocean and their exchange with the atmosphere and the sea floor, and to advance our capacity to predict the response of ocean systems to anthropogenic perturbations.

  8. "Assessment of different bioequivalent metrics in Rifampin bioequivalence study "

    Directory of Open Access Journals (Sweden)

    "Rouini MR


    Full Text Available The use of secondary metrics has become special interest in bioequivalency studies. The applicability of partial area method, truncated AUC and Cmax/AUC has been argued by many authors. This study aims to evaluate the possible superiority of these metrics to primary metrics (i.e. AUCinf, Cmax and Tmax. The suitability of truncated AUC for assessment of absorption extent as well as Cmax/AUC and partial AUC for the evaluation of absorption rate in bioequivalency determination was investigated following administration of same product as test and reference to 7 healthy volunteers. Among the pharmacokinetic parameters obtained, Cmax/AUCinf was a better indicator or absorption rate and the AUCinf was more sensitive than truncated AUC in evaluation of absorption extent.

  9. Quality control for exposure assessment in epidemiological studies

    DEFF Research Database (Denmark)

    Bornkessel, C; Blettner, M; Breckenkamp, J


    In the framework of an epidemiological study, dosemeters were used for the assessment of radio frequency electromagnetic field exposure. To check the correct dosemeter's performance in terms of consistency of recorded field values over the entire study period, a quality control strategy...... was developed. In this paper, the concept of quality control and its results is described. From the 20 dosemeters used, 19 were very stable and reproducible, with deviations of a maximum of +/-1 dB compared with their initial state. One device was found to be faulty and its measurement data had to be excluded...... from the analysis. As a result of continuous quality control procedures, the confidence in the measurements obtained during the field work was strengthened significantly....

  10. Molecular Cloning of Isopentenyl Transferases Genes Family in Malus domestica Borkh.and a Preliminary Functional Analysis of MdlPT5a%苹果异戊烯基转移酶基因家族(MdlPTs)的克隆与MdlPT5a功能分析

    Institute of Scientific and Technical Information of China (English)

    李皓; 张文; 赵旭勉; 任雪芹; 朱元娣


    [目的]克隆苹果(Malus domestica Borkh.)异戊烯基转移酶(isopentenyltransferase,IPT)基因家族MdIPTs,分析MdIPT5a的生理功能,为深入研究MdIPTs在苹果细胞分裂素生物合成途径中的作用和基因的遗传转化提供理论依据.[方法]以‘富士’苹果为试材,利用RACE和苹果基因组信息克隆MdIPTs;利用洋葱表皮和拟南芥原生质体的瞬时表达研究MdIPT5a的亚细胞定位;通过农杆菌介导法遗传转化‘W38’烟草(Nicotiana tabacum cv.Wisconsin 38)过量表达MdIPT5a,RT-PCR鉴定转基因烟草.[结果]克隆了10个MdIPTs的cDNA 序列,其中7个编码细胞分裂素生物合成主要途径中的腺苷-IPTs,具有N端的保守结构域GxxGxGK[S,T]序列,分别位于苹果第13、16、3、11、13、16、6号染色体上,命名为MdIPT1a、MdIPT1b、MdIPT3a、MdIPT3b、MdIPT5a、MdIPT5b和MdIPT7a,均无内含子,编码284-370个氨基酸.MdIPT5a-GFP融合蛋白定位于细胞质中,但不定位于质体内.过量表达MdIPT5a的转基因烟草组培苗生根困难、叶片和不定芽增多.[结论]苹果中腺苷-异戊烯基转移酶基因具有成对高度同源现象,与苹果17条染色体起源于9条始祖染色体的同源起源学说相一致,MdIPT5a具有催化合成细胞分裂素的功能.%[Objective] The aim of this study was to clone a multigene family encoding isopentenyl transferees in Mains domestica, and analyze the biological functions of MdIPT5a, which would provide a basis for in-depth studies of the functions of MdlPTs in cytokinin biosynthesis and genetic transformation. [Method] The MdlPTs were isolated from apple cultivar 'Fuji' by RACE based on the information of apple genome. The subcellular localization of MdIPT5a was transient expressed in onion epidermal cells by the particle bombardment method and in Arabidopsis mesophyll protoplast by the PEG-calcium transfection. MdIPT5a was transferred into tobaccos (Nicotiana tabacum cv. Wisconsin 38) by Agrvbacterium

  11. Strategic risk assessment: A case study of climate change

    Energy Technology Data Exchange (ETDEWEB)

    Beer, T. [CSIRO, Mordialloc, Victoria (Australia). Div. of Atmospheric Research


    The philosophical basis for the on-going international and Australian action on climate change is the precautionary principle. The version of this relevant to Australia is that agreed to by the Australian States and by the Commonwealth of Australia as expressed in the Inter-Governmental Agreement on the Environment (IGAE). This study addresses the following questions: 1. What form of assessment of the risk-weighted consequences of climate change has been undertaken, as required under the precautionary principle? This paper claims that the IPCC process constitutes the risk-weighted assessment that is needed to justify the use of the precautionary principle. 2. Reducing the risk due to climate change requires actions on the basis of some combination of environmental integrity, equity, and economic efficiency as measured by cost-benefit analysis. Is the concept of intergenerational equity consistent with cost-benefit analysis? This paper claims that the problems of valuation over future time-scales, which may range from decades to centuries, make it difficult to apply cost-benefit analysis to the problem.

  12. Development and Implementation of Health Technology Assessment: A Policy Study

    Directory of Open Access Journals (Sweden)

    P Abooee


    Full Text Available Background: To provide an overview of the development of health technology assessment (HTA in Iran since 2007, and to facilitate further development of HTA and its integration into policy making.Methods: Data of this study were collected through key documents (e.g. literature, laws, and other official documentation and analyzed by experts of opinion in form of qualitative methods.Results: Health technology assessment entered to the political agenda in Iran only in 2007 with a strong impetus of an evidence-based medicine movement with the bellow objectives: Institutionalization of evidence-based decision making in Ministry of Health, Creating an localization for structural HTA in Health system of Iran, Setting up training courses in order to educate capable manpower to full up the capacity of the universities, Establishment of a new field in HTA subject in medical universities for MSc and PhD degree, International communication about HTA through national website and possible participation in international Congress.Conclusion: HTA has been established in the healthcare system of Iran but what is needed is a clear political will to push forward the objectives of HTA in Iran. Similar to other countries, advance the regulation on the adoption of new health technologies to improve not only technical or allocate efficiency, but also health equity.

  13. Pain assessment in animal models: do we need further studies?

    Directory of Open Access Journals (Sweden)

    Gigliuto C


    Full Text Available Carmelo Gigliuto,1 Manuela De Gregori,2 Valentina Malafoglia,3 William Raffaeli,3 Christian Compagnone,4 Livia Visai,5,6 Paola Petrini,7 Maria Antonietta Avanzini,9 Carolina Muscoli,8 Jacopo Viganò,11 Francesco Calabrese,11 Tommaso Dominioni,11 Massimo Allegri,2,10 Lorenzo Cobianchi111Anaesthesia and Intensive Care, University of Pavia, Pavia, 2Pain Therapy Service, Fondazione IRCCS Policlinico San Matteo, Pavia, 3ISAL Foundation, Institute for Research on Pain, Torre Pedrera, Rimini, 4Department of Anaesthesia, Intensive Care and Pain Therapy, Azienda Ospedaliera Universitaria Parma, University of Parma, Parma, 5Department of Molecular Medicine, Center for Tissue Engineering (CIT, INSTM UdR of Pavia, University of Pavia, Pavia, 6Department of Occupational Medicine, Ergonomy and Disability, Laboratory of Nanotechnology, Salvatore Maugeri Foundation, IRCCS, Veruno, 7Dipartimento di Chimica, Materiali e Ingegneria Chimica 'G Natta' and Unità di Ricerca Consorzio INSTM, Politecnico di Milano, Milan, 8Department of Health Science, University Magna Grecia of Catanzaro and Centro del Farmaco, IRCCS San Raffaele Pisana, Roma, 9Laboratory of Transplant Immunology/Cell Factory, Fondazione IRCCS Policlinico "San Matteo", Pavia, 10Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, 11University of Pavia, Department of Surgical, Clinical, Paediatric and Diagnostic Science, General Surgery 1, IRCCS Fondazione Policlinico San Matteo, Pavia, ItalyAbstract: In the last two decades, animal models have become important tools in understanding and treating pain, and in predicting analgesic efficacy. Although rodent models retain a dominant role in the study of pain mechanisms, large animal models may predict human biology and pharmacology in certain pain conditions more accurately. Taking into consideration the anatomical and physiological characteristics common to man and pigs (median body size, digestive apparatus

  14. Assessment in child protection : A comparative study Norway - England


    Samsonsen, Vibeke


    Aims: The overall aim of this thesis was to explore the phenomenon of assessment in child protection by comparing two different assessment practices, the Norwegian and the English. Additional aims have been to generate knowledge by interpreting findings from the perspectives of professionals and parents who have experienced assessment, and to contribute to identify central aspects of the use of professional judgement in child protection assessments. The guiding research ques...

  15. Assessment of global phase uncertainty in case-control studies

    Directory of Open Access Journals (Sweden)

    van Houwelingen Hans C


    Full Text Available Abstract Background In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The measure 1 quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of global relative efficiency a minimum value is suggested. Alternatively, we developed methods directly based on the information content of haplotype frequency estimates to obtain global relative efficiency measures: and based on A- and D-optimality, respectively. All three methods are designed for single populations; they can be applied in cases only, controls only or the whole data. Therefore they are not necessarily optimal for haplotype testing in case-control studies. Results A new global relative efficiency measure was derived to maximize power of a simple test statistic that compares haplotype frequencies in cases and controls. Application to real data showed that our proposed method gave a clear and summarizing measure for the case-control study conducted. Additionally this measure might be used for selection of individuals, who have the highest potential for improving power by resolving phase ambiguity. Conclusion Instead of using relative efficiency measure for cases only, controls only or their combined data, we link uncertainty measure to case-control studies directly. Hence, our global efficiency measure might be useful to assess whether data are informative or have enough power for estimation of a specific haplotype risk.

  16. Posttraumatic syringomyelia: volumetric phantom and patient studies using MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Freund, Michael; Habicht, Dirk; Kalvine, Kira; Sartor, Klaus [Department of Neuroradiology, Medical School, University of Heidelberg (Germany); Aschoff, Alfred [Department of Neurosurgery, Medical School, University of Heidelberg (Germany)


    The purpose of this study was to determine the volume of posttraumatic syringomyelia (PTS) based on standard MRI data acquisitions, and to compare the volumes with the neurological deficits of the patients. Firstly, phantom studies were performed using routine T1- (T1W; TR 500 ms, TE 13 ms) spin-echo (SE) images, 3D gradient-echo (GE) images and T2-weighted (T2W) turbo spin-echo (TSE) images (TR 3000 ms, TE 130 ms), in the sagittal plane. The slices were interleaved so that there was no gap. Twelve phantoms simulating a PTS were constructed and filled with fluid. Each volume was exactly measured immediately prior to filling (volumes: 3600-74,000 mm{sup 3}, mean 27,500 mm{sup 3}). In the clinical study 32 patients with PTS were examined using the same protocol. Patients were supine and a phased-array coil was used. The phantom studies revealed measurement errors of within 35%. There were problems defining the boundaries in the small and irregular phantoms as well as in small and irregular PTS, and due to the partial-volume averaging effect. The two small irregular phantoms could only be measured on the axial images. The T2W images in the axial plane showed the best results: measurement accuracy 92%. In the clinical study all examinations were technically successful. The volumes of the PTS ranged between 200 and 19,800 mm{sup 3}; the mean volume was 4075 mm{sup 3}. Our initial results show that the volume measurement of a PTS using standard MRI sequences can help generate more objective and accurate measures of spinal cord lesions, and this may enhance the sensitivity of MRI in detecting disease progression or regression after treatment. (orig.)

  17. Assessing maternal healthcare inequities among migrants: a qualitative study

    Directory of Open Access Journals (Sweden)

    Ligia Moreira Almeida


    Full Text Available Considering pregnancy and motherhood as periods of increased vulnerability in migrant women, to characterize the healthcare provided to this collective, we sought to identify and understand patterns of satisfaction and demand of maternal and child healthcare, assessing women’s perceptions about its quality. The study followed a qualitative methodology (semi-structured interviews for collecting and analysing data (content analysis and was conducted in Porto, the second largest city of Portugal. Participants were 25 recent immigrant mothers from Eastern European countries, Brazil, Portuguese-speaking African countries and six native Portuguese recent mothers (for comparison, contacted through social associations and institutions. Data suggests that healthcare depends not only on accessibility but especially on social opportunities. Equitable public health action must provide individuals and groups the equal opportunity to meet their needs, which may not be achieved by providing the same standard if care to all.

  18. A novel assessment of adolescent mobility: a pilot study

    DEFF Research Database (Denmark)

    Stewart, Tom; Duncan, Scott; Chaix, Basile


    . The recent development of VERITAS - a web-based application nested within a computer-assisted personal interview - allows researchers to assess daily mobility, travel to regular destinations, and perceived neighbourhood boundaries using interactive mapping technology. The aims of this pilot study were to (1......BACKGROUND:The accurate measurement of daily mobility and travel to destinations beyond the residential neighbourhood has been identified as an important but almost systematically overlooked factor when investigating the relationship between exposure to the built environment and physical activity......) demonstrate the feasibility and functionality of using VERITAS in an adolescent sample, and (2) compare urban form characteristics and geometric features of the perceived neighbourhood with traditional neighbourhood delimitations.METHODS:Data were collected and analysed for twenty-eight participants (14 male...

  19. An assessment of the solar irradiance record for climate studies

    Directory of Open Access Journals (Sweden)

    Kopp Greg


    Full Text Available Total solar irradiance, the spatially and spectrally integrated radiant output from the Sun at a mean Sun-Earth distance of 1 astronomical unit, provides nearly all the energy driving the Earth’s climate system. Variations in this energy, particularly over long time scales, contribute to changes in Earth’s climate and have been linked to historical glaciation and inter-glacial periods as well as having a small effect on more recent global warming. Accurate measurements of solar irradiances require measurements above the Earth’s atmosphere. The total solar irradiance spaceborne record began in 1978 and has been uninterrupted since, with over a dozen instruments contributing to the present solar climate data record. I assess the required and achieved accuracies of this record with a focus on its value for climate studies.

  20. Integrated assessment in the Mediterranean: the CIRCE case studies (United States)

    Goodess, C. M.; Agnew, M. D.; Hemming, D.; Giannakopoulos, C.


    The heterogeneous nature of the Mediterranean environment, combined with a wide diversity of economic, social and cultural identities, make this region particularly amenable to integrated research on climate change impacts, vulnerabilities, and adaptive response. Within the framework of the EU FP7 CIRCE project, eleven case-study locations were selected to reflect three generic environments (urban, rural and coastal), to quantify current and future climate change and to assess the potential consequences to human communities and ecosystems at the regional to local scale. The case studies (Athens, Beirut, Alexandria, Tuscany, Apulia, Tel Hadya, Judean Foothills, Gulf of Valencia, Gulf of Oran, Gulf of Gabes, West Nile Delta) were chosen to reflect the east-west and north-south contrasts across the Mediterranean, using common selection criteria. A rigorous common framework, referred to as the CIRCE Case studies Integrating Framework was developed to facilitate a structured and systematic basis for identifying and selecting indicators. Within this framework, climate dynamics is viewed as a key driver of changes in social and biogeophysical systems and is modulated by the inherent dynamics of these systems. The top-down, indicator-based approach was complemented by a bottom-up approach involving local and regional stakeholders. A participatory level of involvement was aimed for, with stakeholder dialogue on an informal basis throughout the project, culminating in a series of more formal regional stakeholder workshops. Identification and construction of physical and socio-economic indicators was the most challenging and time-consuming aspect of the case-study work. A detailed set of selection criteria was defined and the process of reviewing and refining indicators was iterative. Nonetheless, a number of data and methodological challenges were encountered. Despite these issues, indicator linkages diagrams provided a useful preparatory stage for structuring the integrated

  1. Scaling studies and conceptual experiment designs for NGNP CFD assessment

    Energy Technology Data Exchange (ETDEWEB)

    D. M. McEligot; G. E. McCreery


    The objective of this report is to document scaling studies and conceptual designs for flow and heat transfer experiments intended to assess CFD codes and their turbulence models proposed for application to prismatic NGNP concepts. The general approach of the project is to develop new benchmark experiments for assessment in parallel with CFD and coupled CFD/systems code calculations for the same geometry. Two aspects of the complex flow in an NGNP are being addressed: (1) flow and thermal mixing in the lower plenum ("hot streaking" issue) and (2) turbulence and resulting temperature distributions in reactor cooling channels ("hot channel" issue). Current prismatic NGNP concepts are being examined to identify their proposed flow conditions and geometries over the range from normal operation to decay heat removal in a pressurized cooldown. Approximate analyses have been applied to determine key non-dimensional parameters and their magnitudes over this operating range. For normal operation, the flow in the coolant channels can be considered to be dominant turbulent forced convection with slight transverse property variation. In a pressurized cooldown (LOFA) simulation, the flow quickly becomes laminar with some possible buoyancy influences. The flow in the lower plenum can locally be considered to be a situation of multiple hot jets into a confined crossflow -- with obstructions. Flow is expected to be turbulent with momentumdominated turbulent jets entering; buoyancy influences are estimated to be negligible in normal full power operation. Experiments are needed for the combined features of the lower plenum flows. Missing from the typical jet experiments available are interactions with nearby circular posts and with vertical posts in the vicinity of vertical walls - with near stagnant surroundings at one extreme and significant crossflow at the other. Two types of heat transfer experiments are being considered. One addresses the "hot channel" problem, if necessary

  2. A subjective study to evaluate video quality assessment algorithms (United States)

    Seshadrinathan, Kalpana; Soundararajan, Rajiv; Bovik, Alan C.; Cormack, Lawrence K.


    Automatic methods to evaluate the perceptual quality of a digital video sequence have widespread applications wherever the end-user is a human. Several objective video quality assessment (VQA) algorithms exist, whose performance is typically evaluated using the results of a subjective study performed by the video quality experts group (VQEG) in 2000. There is a great need for a free, publicly available subjective study of video quality that embodies state-of-the-art in video processing technology and that is effective in challenging and benchmarking objective VQA algorithms. In this paper, we present a study and a resulting database, known as the LIVE Video Quality Database, where 150 distorted video sequences obtained from 10 different source video content were subjectively evaluated by 38 human observers. Our study includes videos that have been compressed by MPEG-2 and H.264, as well as videos obtained by simulated transmission of H.264 compressed streams through error prone IP and wireless networks. The subjective evaluation was performed using a single stimulus paradigm with hidden reference removal, where the observers were asked to provide their opinion of video quality on a continuous scale. We also present the performance of several freely available objective, full reference (FR) VQA algorithms on the LIVE Video Quality Database. The recent MOtion-based Video Integrity Evaluation (MOVIE) index emerges as the leading objective VQA algorithm in our study, while the performance of the Video Quality Metric (VQM) and the Multi-Scale Structural SIMilarity (MS-SSIM) index is noteworthy. The LIVE Video Quality Database is freely available for download1 and we hope that our study provides researchers with a valuable tool to benchmark and improve the performance of objective VQA algorithms.

  3. LCTL Teachers’ Assessment Knowledge and Practices: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Megan Montee


    Full Text Available Language assessment allows teachers to gather information about student learning and adjust their instructional practices accordingly. When integrated with instruction, assessment can support student-centered teaching by helping instructors understand what students have learned or are able to do and what they still need to know (Shepard, 2000. However, language teachers often receive limited pre-service training in assessment and testing (Malone, 2008. To date, limited empirical work has been conducted about LCTL teacher education and language assessment literacy. This paper explores a teacher training program designed to address the assessment needs of LCTL educators. This program provides a model of evidence-based assessment training that may be useful to other teacher educators. Furthermore, data generated from the project contributes to research about LCTL teacher education and assessment literacy and suggests future directions for work in this area.

  4. Assessing fluvial flood risk in urban environments: a case study

    Directory of Open Access Journals (Sweden)

    Longo Elisa


    Full Text Available Nowadays, floods are among the most impactful calamities regarding costs. Looking at the natural hazards damage data collected in the International Disaster Database (EM-DAT, it is observable a significant increase over the past four decades of both frequency of floods and associated costs. Similarly, dramatic trends are also found by analyzing other types of flood losses, such as the number of people affected by floods, homeless, injured or killed.To deal with the aforementioned rise of flood risk, more and more efforts are being made to promote integrated flood risk management, for example, the Flood Directive 2007/60/EC. The main goals of this research are the estimation of flood damages using the KULTURisk methodology and the comparing of the projected costs with the observed one. The case study is the 2002 flood in Eilenburg. According to KULTURisk methodology, two major classes of data are considered to evaluate flood risk damage: hydraulic data as regards Hazard and economic information to assess Exposure and Vulnerability This study shows the possibility to extend the lesson learned with the Eilenburg case study in other similar contexts.

  5. Assessing conifer ray parenchyma for ecological studies: pitfalls and guidelines

    Directory of Open Access Journals (Sweden)

    Georg evon Arx


    Full Text Available Ray parenchyma is an essential tissue for tree functioning and survival. This living tissue plays a major role for storage and transport of water, nutrients and non-structural carbohydrates (NSC, thus regulating xylem hydraulics and growth. However, despite the importance of rays for tree carbon and water relations, methodological challenges hamper knowledge about ray intra- and inter-tree variability and its ecological meaning. In this study we provide a methodological toolbox for soundly quantifying spatial and temporal variability of different ray features.Anatomical ray features were surveyed in different cutting planes (cross-sectional, tangential, and radial using quantitative image analysis on stem-wood micro-sections sampled from 41 mature Scots pines (Pinus sylvestris. The percentage of ray surface (PERPAR, a proxy for ray volume, was compared among cutting planes and between early- and latewood to assess measurement-induced variability. Different tangential ray metrics were correlated to assess their similarities. The accuracy of cross-sectional and tangential measurements for PERPAR estimates as a function of number of samples and the measured wood surface was assessed using bootstrapping statistical technique. Tangential sections offered the best 3D insight of ray integration into the xylem and provided the most accurate estimates of PERPAR, with 10 samples of 4 mm2 showing an estimate within ±6.0% of the true mean PERPAR (relative 95% confidence interval, CI95, and 20 samples of 4 mm2 showing a CI95 of ±4.3%. Cross-sections were most efficient for establishment of time series, and facilitated comparisons with other widely used xylem anatomical features. Earlywood had significantly lower PERPAR (5.77 vs. 6.18% and marginally fewer initiating rays than latewood. In comparison to tangential sections, PERPAR was systematically overestimated (6.50 vs. 4.92% and required approximately twice the sample area for similar accuracy. Radial

  6. Study of creep cavity growth for power plant lifetime assessment

    Energy Technology Data Exchange (ETDEWEB)

    Wu Rui; Sandstroem, Rolf


    This report aims to the sub project lifetime assessment by creep (livslaengdspredikteringar vid kryp), which is involved in the project package strength in high temperature power plant, KME 708. The physical creep damage includes mainly cavities and their development. Wu and Sandstroem have observed that cavity size increases linearly with increasing creep strain in a 12%Cr steel. Sandstroem has showed that, based on the relations between the nucleation and growth of creep cavities with creep strain, the physical creep damage can be modelled as a function of creep strain. In the present paper the growth of creep cavity radius R in relation to time t and strain {epsilon} in low alloy and 12%Cr steels as well as a Type 347 steel has been studied. The results exhibit that the power law cavity radius with creep time (R-t) and with creep strain (R-{epsilon}) relations are found for these materials at various testing conditions. The power law R-t and R-{epsilon} relations are in most cases dependent and independent on testing conditions, respectively. The empirical power law R-{epsilon} relations give a description of cavity evolution, which can be used for lifetime assessment. Experimental data have also been compared to the estimations by the classical models for cavity growth, including the power law growth due to Hancock, the diffusion growth due to Speight and Harris, the constrained diffusion growths due to Dyson and due to Rice and the enhanced diffusion growth due to Beere. It appears that the constraint diffusion growth models give a reasonable estimation of R-{epsilon} relation in many cases. The diffusion growth model is only applicable for limited cases where the power over t in R-t relation takes about 1/3. The power law and the enhanced diffusion models are found in most cases to overestimate the cavity growth.

  7. A Case Study of Teacher Personal Practice Assessment Theories and Complexities of Implementing Formative Assessment (United States)

    Box, Cathy; Skoog, Gerald; Dabbs, Jennifer M.


    The value and effectiveness of formative assessment in the classroom has gained an increasing amount of attention during the past decade, especially since the publication of seminal work by Black and Wiliam titled "Assessment and Classroom Learning." Since that time, there has been a renewed interest in describing and evaluating teacher…

  8. Use of wearable technology for performance assessment: a validation study. (United States)

    Papi, Enrica; Osei-Kuffour, Denise; Chen, Yen-Ming A; McGregor, Alison H


    The prevalence of osteoarthritis is increasing globally but current compliance with rehabilitation remains poor. This study explores whether wearable sensors can be used to provide objective measures of performance with a view to using them as motivators to aid compliance to osteoarthritis rehabilitation. More specifically, the use of a novel attachable wearable sensor integrated into clothing and inertial measurement units located in two different positions, at the waist and thigh pocket, was investigated. Fourteen healthy volunteers were asked to complete exercises adapted from a knee osteoarthritis rehabilitation programme whilst wearing the three sensors including five times sit-to-stand test, treadmill walking at slow, preferred and fast speeds. The performances of the three sensors were validated against a motion capture system and an instrumented treadmill. The systems showed a high correlation (r(2) > 0.7) and agreement (mean difference range: -0.02-0.03 m, 0.005-0.68 s) with gold standards. The novel attachable wearable sensor was able to monitor exercise tasks as well as the inertial measurement units (ICC > 0.95). Results also suggested that a functional placement (e.g., situated in a pocket) is a valid position for performance monitoring. This study shows the potential use of wearable technologies for assessing subject performance during exercise and suggests functional solutions to enhance acceptance.

  9. Assessment of Corporate Governance in Jordan: An Empirical Study

    Directory of Open Access Journals (Sweden)

    Sinan S. Abbadi


    Full Text Available This paper assesses the reality of corporate governance in Jordan. It identifies the framework of corporate governance, which has here been set into two dimensions – institutionalisations and regulations – and describes the five major principles of corporate governance. The study was carried out by interviews with key employees and the review of related laws and selected annual reports. The study found (1 basic shareholder rights were honoured in decision-making, except for large decisions such as major asset sales; (2 shareholders were not treated equitably in practice, although controllers sometimes took action and prohibited insider trading; (3 the role and rights of stakeholders in corporate governance were respected, and stakeholders had a number of legal protections, which were largely covered in Jordan's Company Law; (4 disclosure and transparency were observed to a large extent, although limited to quantity rather than quality, because Jordan has fully adopted IFRS and ISA and (5 boards largely fulfilled their responsibilities, as these are extensively defined by law and regulation.

  10. Sedentary time assessed by actigraphy and mortality: The Rotterdam Study. (United States)

    Koolhaas, Chantal M; Dhana, Klodian; van Rooij, Frank J A; Kocevska, Desana; Hofman, Albert; Franco, Oscar H; Tiemeier, Henning


    Research suggests that sedentary behavior is a risk factor for mortality. However, most studies rely on questionnaires, which are prone to reporting error. We examined the association between sedentary time assessed by actigraphy and mortality among 1839 participants, aged 45-98years, from the prospective population-based Rotterdam Study, enrolled between 2004 and 2007. Participants wore an actigraph around the wrist for seven days. Sedentary time was evaluated continuously, per 1h/day increase, and categorically in three groups (sedentary behavior and mortality over and beyond other activity measures (including physical activity (PA) and activities of daily living (ADL)) in a final model. During 11years of follow-up (median: 7.5years, interquartile range: 6.6-8.3years), 212 participants (11.5%) died. In the multivariable model, the hazard ratio (HR) and 95% confidence interval (95% CI) per 1 more hour/day sedentary time was 1.09 (1.00, 1.18). The HR (95% CI) after adjustment for PA and ADL was 1.04 (0.96, 1.13). Participants sedentary for ≥11h/day had a higher mortality risk (HR: 1.80, 95% CI: 1.14, 2.84) than those sedentary sedentary behavior is a risk factor for mortality. Further investigation is needed to examine whether this association is distinct from the effect of other measures of activity.

  11. Quick assessment of hopelessness: a cross-sectional study

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    Cheung Yin


    Full Text Available Abstract Background Lengthy questionnaires reduce data quality and impose a burden on respondents. Previous researchers proposed that a single item ("My future seems dark to me" and a 4-item component of the Beck's Hopelessness Scale (BHS can summarise most of the information the BHS provides. There is no clear indication of what BHS cutoff values are useful in identifying people with suicide tendency. Methods In a population-based study of Chinese people aged between 15 and 59 in Hong Kong, the Chinese version of the BHS and the Centre for Epidemiologic Studies – Depression scale were administered by trained interviewers and suicidal ideation and suicidal attempts were self-reported. Receiver operating characteristics curve analysis and regression analysis were used to compare the performance of the BHS and its components in identifying people with suicidality and depression. Smoothed level of suicidal tendency was assessed in relation to scores on the BHS and its component to identify thresholds. Results It is found that the 4-item component and, to a lesser extent, the single item of the BHS perform in ways similar to the BHS. There are non-linear relationship between suicidality and scores on the BHS and the 4-item component; cutoff values identified accordingly have sensitivity and specificity of about 65%. Conclusion The 4-item component is a useful alternative to the BHS. Shortening of psycho-social measurement scales should be considered in order to reduce burden on patients or respondents and to improve response rate.

  12. Comparative study for environmental assessment by program characters

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Suk Chul; Lee, Young Soo; Park, Young Min; Park, Suk Soon; Chung, Kyung Tae; Cho, Hong Yun; Chae, Jang Won; Lee, Sang Don; Lee, Chan Ho; Choi, Joon Kyu; Kim, Kang Joo; Chung, Won Moo; Jin, Jae Yool [Korea Environment Institute, Seoul (Korea)


    The level of environmental assessment in Korea was diagnosed by examining the situation of its model for the entire environmental assessment implemented. Also, it proposed an improvement scheme for its problems to be able to advance. It is expected to be utilized as developing optimum model for Korea and establishing a systematic and concrete guideline for environmental assessment modeling. 244 refs., 65 figs., 28 tabs.

  13. Employing Computer Assisted Assessment (CAA to facilitate formative assessment in the State Secondary School: a case study

    Directory of Open Access Journals (Sweden)

    Effimia Karagianni


    Full Text Available Based on theories of assessment as well as on the pedagogical and administrative advantages Computer Assisted Assessment (CAA has to offer in foreign language learning, the study presented in this paper examines how computers can facilitate the formative assessment of EFL learners and enhance their feeling of responsibility towards monitoring their progress. The subjects of the study were twenty five 14-year-old students attending the third class of a State Gymnasium in Greece. The instruments utilized were questionnaires on motivation and learning styles, three quizzes designed with the software Hot Potatoes, a self–assessment questionnaire and an evaluation questionnaire showing the subjects’ attitudes towards the experience of using computers for assessing purposes. After reviewing formative assessment, CAA and how these two can be combined, the paper focuses on the description of the three class quizzes used in the study. Ιnformation from the questionnaires filled in by students combined with the results of the quizzes, shows how computers can be used to provide continuous ongoing measurement of students’ progress needed for formative assessment. The results are also used to show how students and teachers can benefit from formative CAA and the extent to which such kind of assessment could be applicable in the Greek state school reality.

  14. Thermal Comfort Assessment: A Case Study at Malaysian Automotive Industry

    Directory of Open Access Journals (Sweden)

    A. R. Ismail


    Full Text Available Problem statement: Thermal comfort has a great influence on the productivity and satisfaction of indoor building occupants. The exposure to excessive heat during work may cause discomfort and contributed to low productivity among workers. Malaysia known with its hot and humid weather where in most of the survey study published indicated that workers in Malaysia automotive industries had exposed to excessive temperature while working. The study investigated the thermal comfort level experienced by workers at Malaysian automotive industry. Approach: The study had been conducted at one automotive parts assembly factory in Malaysia. The human subjects for the study constitute operators at tire receiving section of the factory. The environment examined was the relative humidity (%, WBGT, air temperature and radiant temperature (°C of the surrounding workstation area. The environmental factors were measured using Babuc apparatus, which is capable to measure simultaneously those mentioned environmental factors. The time series data of fluctuating level of factors were plotted to identify the significant changes of factors. Then thermal comfort of the workers was assessed by using ASHRAE thermal sensation scale by using Predicted Mean Vote (PMV. Further Predicted Percentage Dissatisfied (PPD was used to estimate the thermal comfort satisfaction of the occupant. Finally the PPD versus PMV were plotted to present the thermal comfort scenario of workers involved in related workstation. Results: The trend of relative humidity curve from the graph also indicated the increasing level of discomfort. The radiant temperature observed seems consistent during the study while there was decreasing of WBGT start from afternoon due to the rain. The study revealed that the PPD value of 54% of the workers population at the workstation are likely to be satisfied with thermal comfort at this station while the PMV index from ASHRAE indicated the value 1

  15. Study on territorial risk assessment in Beibu Gulf of Guangxi (United States)

    Wang, Y.; Hou, L. S.; Zhang, M. S.


    This study is based on the theories of terrestrial exploration risk in the Beibu Gulf Economic Zone in the Guangxi Zhuang Autonomous Region. Using ArcGIS and modelling methods, the spatial distributions of resources and environmental carrying capacity, terrestrial exploration dynamics, and terrestrial exploration potential are studied and evaluated in an integrated way. The results of the study are as follows: Mashan county, Longan county, Luchuan county, et al. have some low-risk land that can be explored, and infrastructure investment should be increased in these locations. Whereas, low-risk terrestrial development is possible in Qinzhou city, Heng county, Longan county, et al. and should be carried out in a planned and gradual fashion. The medium risk regions are distributed all over the region, but are concentrated in the city area of Nanning. However, the middle and north parts of Yulin city, the south part of Chongzuo city, Qinnan district, et al. are also in the same category and priority can be given to improve the quality and efficiency of these regions. The high risk regions, mainly distribute in the Liangqin district, Yining district, Binyang county, et al. This region should focus on the development principles of priority protection, appropriate development, and point-like development. Whereas, the extremely-high-risk areas, of which more than 60% are in Tiandeng county, Daxin county, Shanglin county, et al., are unsuitable for further development. The three-dimensional risk matrix method can make up for the deficiencies of other methods and has broad prospects in regional terrestrial development risk assessment.

  16. Exploring assessment factors contributing to students' study strategies: literature review.

    NARCIS (Netherlands)

    Al-Kadri, H.M.; Al-Moamary, M.S.; Roberts, C.; Vleuten, C.P.M. van der


    "Assessment steers students' learning" is a statement that has been used repeatedly without solid evidence in the literature. This manuscript aims to evaluate the published literatures on the effect of teaching learning environment in particular, the implemented assessment on students' learning appr

  17. Case study applications of the BASINS climate assessment tool (CAT) (United States)

    This EPA report will illustrate the application of different climate assessment capabilities within EPA’s BASINS modeling system for assessing a range of potential questions about the effects of climate change on streamflow and water quality in different watershed settings and us...

  18. Voice Assessment of Student Work: Recent Studies and Emerging Technologies (United States)

    Eckhouse, Barry; Carroll, Rebecca


    Although relatively little attention has been given to the voice assessment of student work, at least when compared with more traditional forms of text-based review, the attention it has received strongly points to a promising form of review that has been hampered by the limits of an emerging technology. A fresh review of voice assessment in light…

  19. Study of occupation health risk assessment on Chinese coal mine

    Institute of Scientific and Technical Information of China (English)

    XIAO Guo-qing; YAN Xiang-nong


    Factors of occupation health hazard were identified and analyzed, and indexes system of occupation health risk assessment were established by applying fuzzy theory and system safety technique, the weights of index system were obtained by AHP, finally a reasonable mathematics model of occupation health risk assessment was accomplished by an example.

  20. The Issue of Subjectivity in Authentic Social Studies Assessment. (United States)

    Nickell, Pat


    Suggests that scoring criteria should be used in order to reduce teacher subjectivity in scoring classroom assessments. Describes scoring criteria as specific expectations made clear in task instructions used to evaluate student work. Provides an example assessment task for high school geography and addresses three common teacher errors. (CMK)

  1. An Action Research Study of Student Self-Assessment in Higher Education (United States)

    Walser, Tamara M.


    Although student self-assessment is considered a critical component of assessment for learning, its use and related research are rare in higher education. This article describes an action research study of self-assessment as an instructional strategy in two university courses. Results indicate that self-assessment exercises provided students the…

  2. Assessing function in patients undergoing joint replacement: a study protocol for a cohort study

    Directory of Open Access Journals (Sweden)

    Wylde Vikki


    Full Text Available Abstract Background Joint replacement is an effective intervention for people with advanced arthritis, although there is an important minority of patients who do not improve post-operatively. There is a need for robust evidence on outcomes after surgery, but there are a number of measures that assess function after joint replacement, many of which lack any clear theoretical basis. The World Health Organisation has introduced the International Classification of Functioning, Disability and Health (ICF, which divides function into three separate domains: Impairment, activity limitations and participation restrictions. The aim of this study is to compare the properties and responsiveness of a selection of commonly used outcome tools that assess function, examine how well they relate to the ICF concepts, and to explore the changes in the measures over time. Methods/design Two hundred and sixty three patients listed for lower limb joint replacement at an elective orthopaedic centre have been recruited into this study. Participants attend the hospital for a research appointment prior to surgery and then at 3-months and 1-year after surgery. At each assessment time, function is assessed using a range of measures. Self-report function is assessed using the WOMAC, Aberdeen Impairment, Activity Limitation and Participation Restriction Measure, SF-12 and Measure Yourself Medical Outcome Profile 2. Clinician-administered measures of function include the American Knee Society Score for knee patients and the Harris Hip Score for hip patients. Performance tests include the timed 20-metre walk, timed get up and go, sit-to-stand-to-sit, step tests and single stance balance test. During the performance tests, participants wear an inertial sensor and data from motion analysis are collected. Statistical analysis will include exploring the relationship between measures describing the same ICF concepts, assessing responsiveness, and studying changes in measures over

  3. Mixture risk assessment: a case study of Monsanto experiences. (United States)

    Nair, R S; Dudek, B R; Grothe, D R; Johannsen, F R; Lamb, I C; Martens, M A; Sherman, J H; Stevens, M W


    Monsanto employs several pragmatic approaches for evaluating the toxicity of mixtures. These approaches are similar to those recommended by many national and international agencies. When conducting hazard and risk assessments, priority is always given to using data collected directly on the mixture of concern. To provide an example of the first tier of evaluation, actual data on acute respiratory irritation studies on mixtures were evaluated to determine whether the principle of additivity was applicable to the mixture evaluated. If actual data on the mixture are unavailable, extrapolation across similar mixtures is considered. Because many formulations are quite similar in composition, the toxicity data from one mixture can be extended to a closely related mixture in a scientifically justifiable manner. An example of a family of products where such extrapolations have been made is presented to exemplify this second approach. Lastly, if data on similar mixtures are unavailable, data on component fractions are used to predict the toxicity of the mixture. In this third approach, process knowledge and scientific judgement are used to determine how the known toxicological properties of the individual fractions affect toxicity of the mixture. Three examples of plant effluents where toxicological data on fractions were used to predict the toxicity of the mixture are discussed. The results of the analysis are used to discuss the predictive value of each of the above mentioned toxicological approaches for evaluating chemical mixtures.

  4. APOC impact assessment studies: baseline ophthalmological findings in Morogoro, Tanzania. (United States)

    Babalola, O E; Maegga, B; Katenga, S; Ogbuagu, F K; Umeh, R E; Seketeli, E; Braide, E


    The goal of the African Programme for Onchocerciasis Control (APOC) is to eliminate Onchocerciasis as a disease of public Health significance and an important constraint to socio-economic development in the 19 none OCP (Onchocerciasis Control Project) countries covered through Community-Directed Treatment with Ivermectin, CDTI. In 1998, impact assessment studies were carried out in Morogoro, Tanzania during which baseline ophthalmological parameters were established. The hypothesis being tested is that CDTI will prevent or delay progression of onchocercal eye lesions and blindness. A total of 425 subjects aged 10 years or more from 14 villages within Bwakira district ofMorogoro region in Tanzania were examined for Snellen visual acuity, ocular microfilaria, lens opacities, uveitis and posterior segment disease especially chorioretinitis and optic nerve disease. Motion Sensitivity Screening Test (MSST) was carried out as well. Microfilaria was present in the anterior chamber of nearly half (49.2%) of all subjects examined. Prevalence of blindness was extremely high at 15.2%. Onchocercal lesions were responsible for blindness in 41.5% of these, followed by cataracts (27.7%), glaucoma (10.8%) and trachoma (6.2%). The main pathway to onchocercal blindness in this population was anterior uveitis with or without secondary cataracts. There is an urgent need to get CDTI underway and institute other horizontal primary eye care measures, especially cataract backlog reduction, in order to reduce the excessive burden of avoidable blindness in this community.

  5. Substances toxiques persistantes (PTS dans les corps gras : État des lieux d’après le rapport du programme des Nations-Unies pour l’environnement (PNUE

    Directory of Open Access Journals (Sweden)

    Narbonne Jean François


    Full Text Available Depuis plus de trente ans, une attention croissante a été portée sur les risques pour la santé humaine posés par la contamination de l’environnement par les substances toxiques persistantes (PTS. Ces composés persistent pendant de longues périodes dans les compartiments abiotiques et biotiques, sont transportés sur de longues distances depuis leurs points sources et s’accumulent chez l’homme et les organismes via les chaînes alimentaires. En 1997, le PNUE propose une liste initiale de 12 substances appelées polluants organiques persistants (POPs : aldrine, endrine, dieldrine, chordane, DDT, heptachlore, toxaphène, mirex, hexachlorobenzène, PCBs, dioxines (PCDDs, furanes (PCDFs. En 2001, de nouveaux composés sont ajoutés sur la liste des PTS en fonction de leurs caractéristiques comme la liposolubilité, leur résistance à la dégradation, leur forte toxicité ou la constance des apports : hexachlorohexane, PAHs, endosulfan, pentachlorophénol, formes organiques des métaux lourds : mercure, étain et plomb, phtalates, PBDEs\\\\PBBs, chlordécone, alkyl phénols, atrazine. Les sources de PTS sont diverses : (1 Utilisation de produits chimiques industriels comme les pesticides ou les emballages, (2 Réservoirs historiques déjà présents dans l’environnement essentiellement dans les sols et les sédiments ou sous forme de stocks périmés, (3 Sous-produits de process, en particulier comme contaminants indésirables de procédés industriels et de combustion. La France a été associée au rapport de la région IV méditerranéenne. Les niveaux dans les compartiments de l’environnement sont rapportés et l’exposition de l’homme via l’alimentation (vecteur essentiel est estimée en fonction des données collectées. Une évaluation des risques associés a été faite quand les données étaient suffisantes (PAHs, PCBs, PCDD\\\\F, Me Hg. Les lipides apparaissent comme vecteurs majeurs des PTS à travers la cha

  6. Physical fitness assessment in multiple sclerosis patients: a controlled study. (United States)

    Guerra, E; di Cagno, A; Mancini, P; Sperandii, F; Quaranta, F; Ciminelli, E; Fagnani, F; Giombini, A; Pigozzi, F


    There is growing evidence to show the effectiveness of physical exercise for multiple sclerosis (MS) patients. Aim of this study was to evaluate aerobic capacity, strength, balance, and the rate of perceived exertion (RPE) after exercise, in ambulatory patients with mild MS and matched control healthy participants. Seventeen MS patients aged 48.09 ± 10.0 years, with mild MS disability (Expanded Disability Status Scale: EDSS 1.5 to 4.5) and 10 healthy sedentary age matched (41.9 ± 11.2 years) subjects volunteered for the study. MS patients underwent medical examination with resting electrocardiogram, arterial blood pressure, EDSS, and Modified Fatigue Impact Scale-MFIS. Both groups also underwent physical assessment with the Berg Balance Scale(,) test (Berg), Six Minutes Walking Test (6MWT), maximal isometric voluntary contraction (MIVC) of forearm, lower limb, shoulder strength test, and the Borg 10-point scale test. The one-way ANOVA showed significant differences for MFIS (F1.19=9.420; p<0.01), Berg (F1.19=13.125; p<0.01), handgrip MIVC (F1.19=4.567; p<0.05), lower limbs MIVC (F1.19=7.429; p<0.01), and 6MWT (F1.19=28.061; p<0.01) between groups. EDSS, Berg test and Borg scores explained 80% of 6MWT variation. Mild grade EDSS patients exhibited impaired balance, muscle strength, and low self pace-6MWT scores, whereas RPE response after the exercise was similar to that of sedentary individuals. Both groups showed similar global physiological adjustments to exercise.

  7. Contaminants in milk and impact of heating: An assessment study

    Directory of Open Access Journals (Sweden)

    Vandana Awasthi


    Full Text Available Background: The major contaminants usually encountered in milk and milk products include pesticide residues, heavy metals, and aflatoxin M1 (AFM1. Primarily, milk get contaminated before milching, from the cattle feed, from sources/materials used during the processing of milk as well as improper handling of the milk during the pre- and postprocessing period. Objective: The purpose of this study was to evaluate the effect of household practices on milk contaminants. Materials and Methods: Samples of pasteurized as well as unpasteurized milk (Vendor′s milk were analyzed for AFM1, pesticide residues, and heavy metals. Simulating the household practices, the impact of boiling on these contaminants was assessed. Results: The contaminant Aflatoxin M1 (AFM1 was detected at a concentration ranging from 0.071-0.075 ppb in unpasteurized as well as pasteurized milk samples analyzed during the course of study. Moreover, boiling had no impact on the quantity of AFM1 present in the milk. Pesticides and heavy metal contents were found to be within acceptable limits in all the milk samples tested. Conclusion: Mycotoxins especially aflatoxins in cattle feed and their consequential presence in milk and milk products is a serious concern world over as they are reported carcinogens. These fungal toxins are resistant to high temperatures and may lead to various health hazards. Preventive steps must be taken at each stage to ensure good quality of milk and milk products free from these contaminants. Awareness programs and education for the dairy farmers and milk processors may be helpful in this regard.

  8. FY11 Facility Assessment Study for Aeronautics Test Program (United States)

    Loboda, John A.; Sydnor, George H.


    This paper presents the approach and results for the Aeronautics Test Program (ATP) FY11 Facility Assessment Project. ATP commissioned assessments in FY07 and FY11 to aid in the understanding of the current condition and reliability of its facilities and their ability to meet current and future (five year horizon) test requirements. The principle output of the assessment was a database of facility unique, prioritized investments projects with budgetary cost estimates. This database was also used to identify trends for the condition of facility systems.

  9. Clinical assessment of transthoracic echocardiography skills: a generalizability study

    DEFF Research Database (Denmark)

    Nielsen, Dorte Guldbrand; O'Neill, Lotte; Jensen, Signe


    Context: Transthoracic echocardiography (TTE) is a widely used cardiac imaging technique that all cardiologists should be able to perform competently. Traditionally, TTE competence has been assessed by unstructured observation or in test situations separated from daily clinical practice. An objec...

  10. Ethics and Computer-Assisted Assessment: Three Case Studies. (United States)

    Jacob, Susan; Brantley, John C.


    Three ethical-legal case incidents involving computer-assisted psychodiagnostic assessment in the schools are presented. Each case is analyzed in terms of applicable laws, ethical codes, and standards for professional practice. (Author)

  11. Stealth Assessment in ITS - A Study for Developmental Dyscalculia


    Klingler, Severin; Käser, Tanja; Busetto, Alberto Giovanni; Solenthaler, Barbara; Kohn, Juliane; von Aster, Michael; Gross, Markus


    Intelligent tutoring systems are adapting the curriculum to the needs of the student. The integration of stealth assessments of student traits into tutoring systems, i.e. the automatic detection of student characteristics has the potential to re?ne this adaptation. We present a pipeline for integrating automatic assessment seamlessly into a tutoring system and apply the method to the case of developmental dyscalculia (DD). The proposed classi?er is based on user inputs only, allowing non-intr...

  12. Formative Assessment in ESP Teaching:An Empirical Study

    Institute of Scientific and Technical Information of China (English)



    Based on analysis of learners’needs of English for Specific Purposes (ESP) and in accordance with the actual college ESP teaching, the author conducted a one-term comparative exploration on the application of formative assessment for ESP teaching. The results revealed the positive effects of formative assessment on those participants ’ESP learning, which can be a fa⁃vorable inspiration for the further research of ESP teaching.

  13. A Study on Public Participation in Environmental Impact Assessments

    Institute of Scientific and Technical Information of China (English)



    China's legislature on the environmental impact assessments contains related provisions on public participation as an important element of institutions in this field. So far, however, the stipulation remains at the level of a plain statement of principle both substantially and procedurally. The newly enacted Law on the Assessment of the Environment Impact has seen great progress in provisions for public participation if compared with similar statutes enacted in the past legislation. However, there is a gap in the procedures,

  14. Assessment and Recognition of Non-Formal and Informal Learning in University Studies

    Directory of Open Access Journals (Sweden)

    Nijolė Burkšaitienė


    Full Text Available The paper explores the problem of assessment and recognition of non-formal and informal learning in university studies: it presents results of the analysis into European and world universities’ experience in assessing and recognizing adults’ learning that occurs in different learning environments, general principles guiding the assessment and recognition of prior learning, models of assessment as well as results of a survey into adults’ needs of assessment and recognition of prior learning in Lithuania.

  15. Assessing uncertainties in solute transport models: Upper Narew case study (United States)

    Osuch, M.; Romanowicz, R.; Napiórkowski, J. J.


    This paper evaluates uncertainties in two solute transport models based on tracer experiment data from the Upper River Narew. Data Based Mechanistic and transient storage models were applied to Rhodamine WT tracer observations. We focus on the analysis of uncertainty and the sensitivity of model predictions to varying physical parameters, such as dispersion and channel geometry. An advection-dispersion model with dead zones (Transient Storage model) adequately describes the transport of pollutants in a single channel river with multiple storage. The applied transient storage model is deterministic; it assumes that observations are free of errors and the model structure perfectly describes the process of transport of conservative pollutants. In order to take into account the model and observation errors, an uncertainty analysis is required. In this study we used a combination of the Generalized Likelihood Uncertainty Estimation technique (GLUE) and the variance based Global Sensitivity Analysis (GSA). The combination is straightforward as the same samples (Sobol samples) were generated for GLUE analysis and for sensitivity assessment. Additionally, the results of the sensitivity analysis were used to specify the best parameter ranges and their prior distributions for the evaluation of predictive model uncertainty using the GLUE methodology. Apart from predictions of pollutant transport trajectories, two ecological indicators were also studied (time over the threshold concentration and maximum concentration). In particular, a sensitivity analysis of the length of "over the threshold" period shows an interesting multi-modal dependence on model parameters. This behavior is a result of the direct influence of parameters on different parts of the dynamic response of the system. As an alternative to the transient storage model, a Data Based Mechanistic approach was tested. Here, the model is identified and the parameters are estimated from available time series data using

  16. The effect of comorbidities on COPD assessment: a pilot study

    Directory of Open Access Journals (Sweden)

    Weinreich UM


    Full Text Available Ulla Møller Weinreich,1–3 Lars Pilegaard Thomsen,2 Barbara Bielaska,4 Vania Helbo Jensen,5,6 Morten Vuust,4 Stephen Edward Rees2 1Department of Respiratory Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Respiratory and Critical Care Group (RCARE, Centre for Model-Based Medical Decision Support Systems, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark; 3The Clinical Institute, Aalborg University Hospital, Aalborg, Denmark; 4Department of Radiology, Vendsyssel Hospital, Hjørring, Denmark; 5Department of Radiology, Horsens Regional Hospital, Horsens, Denmark; 6Department of Radiology, Aalborg University Hospital, Aalborg, Denmark Introduction: Patients with chronic obstructive pulmonary disease (COPD frequently suffer from comorbidities. COPD severity may be evaluated by the Global initiative for chronic ­Obstructive Lung Disease (GOLD combined risk assessment score (GOLD score. Spirometry, body plethysmography, diffusing capacity of the lung for carbon monoxide (DLCO, and high-resolution computed tomography (HR-CT measure lung function and elucidate pulmonary pathology. This study assesses associations between GOLD score and measurements of lung function in COPD patients with and without (≤1 comorbidities. It evaluates whether the presence of comorbidities influences evaluation by GOLD score of COPD severity, and questions whether GOLD score describes morbidity rather than COPD severity.Methods: In this prospective study, 106 patients with stable COPD were included. Patients treated for lung cancer were excluded. Demographics, oxygen saturation (SpO2, modified Medical Research Council Dyspnea Scale, COPD exacerbations, and comorbidities were recorded. Body plethysmography and DLCO were measured, and HR-CT performed and evaluated for emphysema and airways disease. COPD severity was stratified by the GOLD score. Correlation analyses: 1 GOLD score, 2 emphysema grade, and 3 airways disease and lung

  17. Case studies in making assessment efficient while developing student professionalism and managing transition (United States)

    Rossiter, J. A.


    It is known that assessment drives learning and hence a good assessment design is key to effective student development. This paper gives some case studies in effective assessment strategies within engineering. The main contribution is to demonstrate how one can simultaneously meet a number of requirements with individual assessments and therefore be efficient in both the student and staff assessment load. The paper also proposes that assessments should be challenging and the benefits of expecting students to rise to this challenge and also how one can meet many independent learning objectives in a single assignment in order to manage the overall assessment load for staff and students.

  18. Self-Assessment of Word Knowledge with Graded Readers: A Preliminary Study (United States)

    Wan-a-rom, Udorn


    The study investigated how second language (L2) learners self-assessed word knowledge on a page of text taken from a graded reader. The case study subjects were five Thai high school learners of English. They were asked to assess their word knowledge using a page of continuous text. Data gained through observation, interviews, self-assessment and…

  19. Program Level Assessment: A Case Study for a University Clothing and Textile Major (United States)

    Yun, Zee-Sun; Frazier, Barbara J.


    This paper presents a framework for program assessment and a case study in assessment for a university clothing and textile program in family and consumer sciences. Assessment activities and the process implemented by the Textile and Apparel Studies (TAS) major at Western Michigan University are explained. The process adopts the International…

  20. A Phenomenological Case Study: Teacher Bias Effects on Early Education Assessments (United States)

    Reynolds, Rebecca Jeannine


    This qualitative phenomenological case study explored the lived experiences of a purposive sample of 20 current and past early education teachers who have experience in assessing children through observational assessment. The purpose of this study was to determine if bias affects the documentation of observational assessment and the implementation…

  1. Quality Assessment of University Studies as a Service: Dimensions and Criteria (United States)

    Pukelyte, Rasa


    This article reviews a possibility to assess university studies as a service. University studies have to be of high quality both in their content and in the administrative level. Therefore, quality of studies as a service is an important constituent part of study quality assurance. When assessing quality of university studies as a service, it is…

  2. Assessment in the Kindergarten Classroom: An Empirical Study of Teachers' Assessment Approaches (United States)

    Pyle, Angela; DeLuca, Christopher


    Within the current accountability framework of public education, kindergarten teachers face the challenge of balancing traditional developmental programing and current academically oriented curriculum. Central to this challenge is teachers' uses of assessment to measure and communicate student learning in relation to their curricular stance.…

  3. Climate Change Vulnerability Assessments: Four Case Studies of Water Utility Practices (2011 Final) (United States)

    EPA has released the final report titled, Climate Change Vulnerability Assessments: Four Case Studies of Water Utility Practices. This report was prepared by the National Center for Environmental Assessment's Global Climate Research Staff in the Office of Research and D...

  4. Relations between student perceptions of assessment authenticity, study approaches and learning outcome

    NARCIS (Netherlands)

    Gulikers, J.T.M.; Bastiaens, Th.J.; Kirschner, P.A.; Kester, L.


    This article examines the relationships between perceptions of authenticity and alignment on study approach and learning outcome. Senior students of a vocational training program performed an authentic assessment and filled in a questionnaire about the authenticity of various assessment characterist

  5. [Indices of static and dynamic components of pressure load (assessed by 24-hour blood pressure monitoring) and the state of renal function in patients with essential hypertension]. (United States)

    Zelveian, P A; Buniatian, M S; Oshchepkova, E V; Lazareva, N V; Rogoza, A N


    Aim of this study was to evaluate possible relationship between parameters of blood pressure (BP) profile and glomerular filtration rate in patients (pts) with I-II stage essential hypertension (EH). Material and methods. We studied 120 pts (97 men), aged 23-65 (50,2+/-0,6) years with I (n=98) and II (n=22) stage EH. In BP profile (SL-90207) we calculated 24-hour, daytime, nighttime values of systolic, diastolic, pulse pressures (SBP, DBP, PP), time load (TL), variability and nocturnal fall (NF) of BP. The state of renal function was assessed by measurement of glomerular filtration rate (GFR) calculated by the Cockcroft formula. Results. After nonlinear statistical analysis by Gauss-Newton all patients were divided into three groups according to GFR tertiles. Significant differences were found between these groups by 24-hour, nighttime and daytime values of SBP and DBP. Values of SBP were the lowest in group II. In group II lowest values of PP were also observed, but statistically significant differences were found only in nocturnal PP values between groups II and III. There were no significant differences between groups by TL and NF of BP. In group Ill (high GFR) variability of daytime values of SBP and DBF were significantly higher. Univariate correlation analysis showed statistically significant negative relationship between GFR and nocturnal PP in patients with lowest level of GFR. Positive correlations between nocturnal values of PP and GFR in groups II and III were also observed. Conclusion. These results indicated the presence of strong relationship between high values of nocturnal PP and decreasing of glomerular filtration rate in patients with EH and thus confirmed significance of "constant" and "dynamic" components of pressure load as a marker of impairment of renal function.


    Directory of Open Access Journals (Sweden)

    K. Musungu


    Full Text Available Participatory GIS (PGIS has been prescribed by scholars who sought to find a means to enable more equitable access to GIS data, diversifying the types of knowledge captured by a GIS and re-engineering GIS software. The popularity of PGIS is evident in the various studies and contexts in which it has been utilised. These include studies in risk assessment, land administration, resource management, crime mapping and urban design to mention but a few. Despite the popularity of PGIS as a body of research, little has been done in the analysis of the quality of PGIS information. The study investigated the use of data quality criteria commonly used in traditional GIS systems and shows that it is possible to apply the criteria used in traditional GIS to PGIS. It provides a starting point for PGIS studies to assess the quality of the product. Notably, this a reflective exercise on one case study, but the methodologies used in this study have been replicated in many others undertaken by Community Based Organisations as well as Non-Governmental Organisations. Therefore the findings are relevant to such projects.

  7. Assessing Spatial Data Quality of Participatory GIS Studies: a Case Study in Cape Town (United States)

    Musungu, K.


    Participatory GIS (PGIS) has been prescribed by scholars who sought to find a means to enable more equitable access to GIS data, diversifying the types of knowledge captured by a GIS and re-engineering GIS software. The popularity of PGIS is evident in the various studies and contexts in which it has been utilised. These include studies in risk assessment, land administration, resource management, crime mapping and urban design to mention but a few. Despite the popularity of PGIS as a body of research, little has been done in the analysis of the quality of PGIS information. The study investigated the use of data quality criteria commonly used in traditional GIS systems and shows that it is possible to apply the criteria used in traditional GIS to PGIS. It provides a starting point for PGIS studies to assess the quality of the product. Notably, this a reflective exercise on one case study, but the methodologies used in this study have been replicated in many others undertaken by Community Based Organisations as well as Non-Governmental Organisations. Therefore the findings are relevant to such projects.

  8. Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin (United States)

    Overman, Michael J.; Morris, Van; Moinova, Helen; Manyam, Ganiraju; Ensor, Joe; Lee, Michael S.; Eng, Cathy; Kee, Bryan; Fogelman, David; Shroff, Rachna T.; LaFramboise, Thomas; Mazard, Thibault; Feng, Tian; Hamilton, Stanley; Broom, Bradley; Lutterbaugh, James; Issa, Jean-Pierre; Markowitz, Sanford D.; Kopetz, Scott


    Purpose Hypermethylation of promoter CpG islands (CIMP) has been strongly implicated in chemotherapy resistance and is implicated in the pathogenesis of a subset of colorectal cancers (CRCs) termed CIMP-high. Experimental Design This phase I/II study in CRC (phase II portion restricted to CIMP-high CRC), treated fluoropyrimidine/oxaliplatin refractory patients with azacitidine (75 mg/m2/day subcutaneously D1-5) and CAPOX (capecitibine and oxaliplatin) every three weeks. Results Twenty-six patients (pts) were enrolled in this study: 15 pts (12 treated at MTD) in phase I and 11 pts in phase II. No dose limiting toxicities were observed. A total of 14 pts were CIMP-high. No responses were seen. CIMP-high status did not correlate with efficacy endpoints [stable disease (SD) or progression-free survival (PFS)] or baseline vimentin methylation level. Changes in vimentin methylation over time did not correlate with efficacy outcomes. Baseline methylated vimentin correlated with tumor volume (P<0.001) and higher levels of baseline methylation correlated with the obtainment of stable disease (P=0.04). Conclusions Azacitidine and CAPOX were well tolerated with high rates of stable disease in CIMP-high pts, but no objective responses. Serum methylated vimentin may be associated with benefit from a regimen including a hypomethylation agent, although this study is not able to separate a potential prognostic or predictive role for the biomarker. PMID:27542211

  9. Study of Value Assessment Model of Forest Biodiversity Based on the Habitat Area in China

    Directory of Open Access Journals (Sweden)

    Ying Zhang


    Full Text Available Forest biodiversity is an important part of biodiversity. There is an essential significance of studying forest biodiversity assessment for promoting the conservation of biodiversity and enhancing biodiversity management in China. This study collected forest biodiversity habitat area, output value of forestry and so on forest biodiversity assessment-related data from 2001 to 2010 in China and using optimal control methods in cybernetics to establish value assessment model of forest biodiversity based on the data of habitat area, as well as calculated the optimal price for forest biodiversity assessment. The result showed that forest biodiversity habitat assessment of the optimal price is 9,970 RMB Yuan/ha and there is a dynamic model for forest biodiversity assessment. Finally, the study suggested that studies of forest biodiversity assessment in China, in particular, studying of valuation of forest biodiversity should consider using shadow price and the social, economic and other factors should be taken into account

  10. Quantum Mechanics Concept Assessment: Development and Validation Study (United States)

    Sadaghiani, Homeyra R.; Pollock, Steven J.


    As part of an ongoing investigation of students' learning in first semester upper-division quantum mechanics, we needed a high-quality conceptual assessment instrument for comparing outcomes of different curricular approaches. The process of developing such a tool started with converting a preliminary version of a 14-item open-ended quantum…

  11. Institutional Assessment of Student Information Literacy Ability: A Case Study (United States)

    Chan, Christopher


    With increasing interest in the assessment of learning outcomes in higher education, stakeholders are demanding concrete evidence of student learning. This applies no less to information literacy outcomes, which have been adopted by many colleges and universities around the world. This article describes the experience of a university library in…

  12. Red list assessment of European habitat types. A feasibility study

    NARCIS (Netherlands)

    Rodwell, J.S.; Janssen, J.A.M.; Gubbay, S.; Schaminee, J.H.J.


    This report presents an achievable methodology for the Red List assessment of European habitats in terrestrial, freshwater and marine realms, outlines a process that will deliver such evaluations and gives an indication of resources needed. It shows how the EUNIS habitat classification can be employ

  13. A Validity Study of the Salter Environmental Type Assessment. (United States)

    Salter, Daniel W.


    Correlational analyses of data from 202 students on the Work Environment Scale and Salter Environmental Type Assessment (SETA) supported concurrent validity. Factor analysis identified three factors accounting for 70% of variance: positive work settings, structure, and work pressure/task orientation. SETA appears useful as a commensurate Myers…

  14. A Comparative Study of Three Vibration Based Damage Assessment Techniques

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Rytter, A.

    Three different vibration based damage assessment techniques have been compared. One of the techniques uses the ratios between changes in experimentally and theoretically estimated natural frequencies, respectively, to locate a damage. The second technique relies on updating of an FEM based...

  15. Examining the Implicit Relational Assessment Procedure: Four Preliminary Studies (United States)

    Drake, Chad E.; Kellum, Karen Kate; Wilson, Kelly G.; Luoma, Jason B.; Weinstein, Jonathan H.; Adams, Catherine H.


    The Implicit Relational Assessment Procedure (IRAP) is a relatively new measure of implicit cognition that tests cognition as relational behavior instead of an associative activity and thus may provide a more specific measure of cognitive repertoires, including those for social biases, than better known implicit measures such as the Implicit…

  16. Challenging issues in assessing analytical similarity in biosimilar studies

    Directory of Open Access Journals (Sweden)

    Chow SC


    Full Text Available Shein-Chung Chow Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA Abstract: For assessing biosimilarity of biosimilar products, the US Food and Drug Administration (FDA proposed a stepwise approach for providing totality-of-the-evidence of similarity between a proposed biosimilar product and a US-licensed (reference product. The stepwise approach starts with an assessment of critical quality attributes (CQAs that are relevant to clinical outcomes in structural and functional characterization in manufacturing process of the proposed biosimilar product. The FDA suggests that these critical quality–relevant attributes be identified and classified into three tiers depending their criticality or risk ranking. To assist the sponsors, the FDA also suggests some statistical approaches for the assessment of analytical similarity for CQAs from different tiers, namely equivalence test for Tier 1, quality range approach for Tier 2, and descriptive raw data and graphical comparison for Tier 3. In this paper, challenging issues to the FDA's recommended approaches are discussed followed by alternative methods for the assessment of analytical similarity (mainly for CQAs from Tier 1. Keywords: stepwise approach, critical quality attribute, CQA, equivalence test, quality range approach 

  17. Alternative Assessment: Implications for Social Studies. ERIC Digest. (United States)

    Nickell, Pat

    Alternative forms of evaluating student progress are changing testing or assessment in U.S. schools. From the teacher-made to the standardized test, the familiar over-emphasis on multiple-choice items is giving way to expanded generative formats in which students are called upon to demonstrate mastery through applications in which they use complex…

  18. Beyond the Bubble in History/Social Studies Assessments (United States)

    Breakstone, Joel; Smith, Mark; Wineburg, Sam


    Teachers need tools and assessments that will prepare students to meet the ambitious goals laid out by the Common Core State Standards. The multiple-choice tests that dominate in history will not prepare students to analyze primary and secondary sources, cite textual evidence to support arguments, consider the influence of an author's perspective,…

  19. Comparison of tools for assessing the methodological quality of primary and secondary studies in health technology assessment reports in Germany

    Directory of Open Access Journals (Sweden)

    Walter, Ulla


    Full Text Available Health care policy background: Findings from scientific studies form the basis for evidence-based health policy decisions. Scientific background: Quality assessments to evaluate the credibility of study results are an essential part of health technology assessment reports and systematic reviews. Quality assessment tools (QAT for assessing the study quality examine to what extent study results are systematically distorted by confounding or bias (internal validity. The tools can be divided into checklists, scales and component ratings. Research questions: What QAT are available to assess the quality of interventional studies or studies in the field of health economics, how do they differ from each other and what conclusions can be drawn from these results for quality assessments? Methods: A systematic search of relevant databases from 1988 onwards is done, supplemented by screening of the references, of the HTA reports of the German Agency for Health Technology Assessment (DAHTA and an internet search. The selection of relevant literature, the data extraction and the quality assessment are carried out by two independent reviewers. The substantive elements of the QAT are extracted using a modified criteria list consisting of items and domains specific to randomized trials, observational studies, diagnostic studies, systematic reviews and health economic studies. Based on the number of covered items and domains, more and less comprehensive QAT are distinguished. In order to exchange experiences regarding problems in the practical application of tools, a workshop is hosted. Results: A total of eight systematic methodological reviews is identified as well as 147 QAT: 15 for systematic reviews, 80 for randomized trials, 30 for observational studies, 17 for diagnostic studies and 22 for health economic studies. The tools vary considerably with regard to the content, the performance and quality of operationalisation. Some tools do not only include the

  20. Questioning western assessment of trauma among Tibetan torture survivors. A quantitative assessment study with comments from Buddhist Lamas

    DEFF Research Database (Denmark)

    Elsass, Peter; Carlsson, Jessica; Jespersen, Kristian;


    not have an influence on the level of distress. After the assessment study, eight Tibetan lamas were interviewed about their views on our methods and results. They questioned the validity of our western rating scales and explained that our results might be influenced by the Tibetan culture, which among......Our study falls in line with the numerous studies providing a critique of the use of western diagnostic instruments for assessing trauma in a cross-cultural context. Our purpose has been to give evidence for the Tibetan torture survivors' degree of traumatisation and for their use of spirituality...... to overcome their difficult situation. In addition we wanted to question the use of our western methods in an Asian context. 102 tortured refugees attended a formalised needs assessment including neuropsychological and psychological measures of Post Traumatic Stress Disorder (PTSD) and the Hopkins Symptom...

  1. Review of pressurized thermal shock studies of large scale reactor pressure vessels in Hungary

    Directory of Open Access Journals (Sweden)

    Tamás Fekete


    Full Text Available In Hungary, four nuclear power units were constructed more than 30 years ago; they are operating to this day. In every unit, VVER-440 V213-type light-water cooled, light-water moderated, ressurized water reactors are in operation. Since the mid-1980s, numerous researches in the field of Pressurized Thermal Shock (PTS analyses of Reactor Pressure Vessels (RPVs have been conducted in Hungary; in all of them, the concept of structural integrity was the basis of research and development. During this time, four large PTS studies with industrial relevance have been completed in Hungary. Each used different objectives and guides, and the analysis methodology was also changing. This paper gives a comparative review of the methodologies used in these large PTS Structural Integrity Analysis projects, presenting the latest results as well

  2. Self-Assessment in Higher Education: Experience in Using a Metacognitive Approach in Five Case Studies (United States)

    Mok, Magdalena Mo Ching; Lung, Ching Leung; Cheng, Doris Pui Wah; Cheung, Rebecca Hun Ping; Ng, Mei Lee


    This study describes the use of a metacognitive approach for self-assessment of teacher education students. The design of the study was guided by the principles of learning-oriented assessment and the centrality of reflection for teachers. The study comprised five case studies undertaken in five teacher education programmes. In each programme,…

  3. Risk Assessment of Vertical Breakwaters -- A Case Study in Turkey

    Institute of Scientific and Technical Information of China (English)

    Can Elmar BALAS; Levent KOC


    In the reliability-risk assessment, the second order reliability index (βⅡ) method and the Conditional ExpectationMonte Carlo (CEMC) simulation are interrelated as a new Level Ⅲ approach for the analysis of the safety level of theDalaman yacht harbor vertical wall breakwater in Turkey. The missing wave data of the Dalaman measurement station arehindcasted by use of muhi-layer feed-forward neural networks with the steepest descent and conjugate gradient algorithms.The structural failure probabilities of sliding and overturning failure modes are forecasted by approximation of the failure sur-face with a second-degree polynomial of an equal curvature at the design point. In the new approach, for each randomlygenerated load and tide combination, the joint failure probability reflects both the occurrence probability of loading conditionand the structural failure risk at the limit state. The approach can be applied to risk assessment of vertical breakwaters inshort CPU durations of portable computers.

  4. A Study of Arbitrations in Pennsylvania's Writing Assessment. (United States)

    Masters, James R.

    In 1991 Pennsylvania began implementation of a direct writing assessment at the sixth-grade and ninth-grade levels. A total of 18,758 sixth graders and 16,575 ninth graders wrote a response to 1 of 9 prompts reflecting 3 modes of writing. A six-point holistic scale was used to score the papers, with two readers scoring each paper. A third reader,…

  5. Viability Assessment Report on TTRDP GMTI Constallation Study (United States)


    satellite orientation . Figure 12. Comparative detection analysis on selected targets 5.2.4 Detection Gap Assessment Besides the constellation size...ground segment from assigning existing tracks to radar sensors. • The satellite orientation at the simulation epoch time. 0 5 10 15 20 25 30 Ta nk...configuration with its larger constellation size still falls behind 27/9/3 3600 RAAN configurations. This again is attributed to the satellite

  6. Assessment Criteria for Competency-Based Education: A Study in Nursing Education (United States)

    Fastré, Greet M. J.; van der Klink, Marcel R.; Amsing-Smit, Pauline; van Merriënboer, Jeroen J.


    This study examined the effects of type of assessment criteria (performance-based vs. competency-based), the relevance of assessment criteria (relevant criteria vs. all criteria), and their interaction on secondary vocational education students' performance and assessment skills. Students on three programmes in the domain of nursing and care…

  7. The Psychometric Properties of Scales that Assess Market Orientation and Team Leadership Skills: A Preliminary Study (United States)

    Kline, Theresa J. B.


    This study assessed the psychometric properties of two scales that can be used in predicting team performance: specifically how team members assess the market orientation of their work unit as well the leadership skills present in the team. The first scale is a three-dimensional assessment of the unit's market orientation (innovative, process, or…

  8. Toward World-Class Standards: A Research Study Linking International and National Assessments. (United States)

    Pashley, Peter J.; Phillips, Gary W.

    This study investigates a linking of the 1991 International Assessment of Educational Progress (IAEP) and the 1992 National Assessment of Educational Progress (NAEP) mathematics assessments. Data to allow such a linking were collected in 1992 from students in the United States who were administered both instruments. Modeling was done using a…

  9. 75 FR 51806 - Climate Change Vulnerability Assessment: Four Case Studies of Water Utility Practices (United States)


    ...-0701] Climate Change Vulnerability Assessment: Four Case Studies of Water Utility Practices AGENCY...-day public comment period for the draft document titled, ``Climate Change Vulnerability Assessment... utilities to assess their vulnerability to future climate change. The report is intended to illustrate...

  10. Race and Writing Assessment. Studies in Composition and Rhetoric. Volume 7 (United States)

    Inoue, Asao B., Ed.; Poe, Mya, Ed.


    "Race and Writing Assessment" brings together established and up-and-coming scholars in composition studies to explore how writing assessment needs to change in order to account for the increasing diversity of students in college classrooms today. Contributors identify where we have ignored race in our writing assessment approaches and explore…

  11. Teaching Writing in the Shadow of Standardized Writing Assessment: An Exploratory Study (United States)

    Brimi, Hunter


    This exploratory study results from interviews with five high school English teachers regarding their writing instruction. The researcher sought to answer these questions: (1) How had the Tennessee Comprehensive Assessment Program's (TCAP) Writing Assessment affected their teaching as gauged by the teachers' statements regarding the assessment,…

  12. What University Students Think about Assessment: A Case Study from Italy (United States)

    Pastore, Serafina; Pentassuglia, Monica


    Nowadays, assessment is widely recognized as a key element in higher education systems. Current studies are moving towards the revision of traditional modalities of testing, the individuation of alternative forms of assessment, and, above all, the analysis of conceptions that teachers and students have about assessment. The present research is…

  13. Studies towards assessing the effects of aviation on climate (United States)

    Khodayari, Arezoo

    Emissions from aviation are an important component in the overall concerns about the effects of human activities on climate. Aviation emissions modify the chemical and physical properties of the upper troposphere and lower stratosphere (UTLS) in various ways. Aircraft emit gases and particles that can either directly or indirectly affect climate and air quality, including: carbon dioxide (CO2); nitrogen oxides (NOx) that can increase ozone (O3) production and increase the destruction of methane (CH4); water vapor that under certain atmospheric conditions can lead to contrail formation; and soot and other particles that along with contrails can affect the amount and characteristics of cirrus clouds. Soot and sulfate particles can also change the cloudiness by acting as cloud condensation nuclei. Due to the high growth in air traffic that is projected to continue, it is important to understand the effects of aviation on air quality and climate. Based on then existing analyses of the emissions and their effects, the aviation contribution in changing the radiative forcing on the climate system was about 5% of the total human-related emissions (relative to 1750) in 2005 (Lee et al., 2009). This contribution is a result of various effects, especially the direct effects of CO2, NOx-induced effects, aerosol direct and indirect effects, and increased cloudiness from contrail formation and aerosols acting as cloud condensation nuclei. One of the main challenges of the aviation scientific community has been to increase the level of scientific understanding of these effects, especially with respect to those most uncertain (i.e. NOx effects, contrail-cirrus and aerosol effects). Another challenge has been to develop a simple climate model (SCM) that has the level of sophistication necessary to accurately assess aviation induced climate effects while being easy to use by policy makers for use in policy considerations. The main objectives in this study were: (1) to evaluate the

  14. A Study of an Intelligent Battlefield Damage Assessment System Based on a Multi-agent System

    Institute of Scientific and Technical Information of China (English)

    LIU Xiang-kai; DAI Wan-jun; TANG Yan-feng; WANG Jia-ning


    Battlefield damage assessment is the key to Battlefield Damage Assessment and Repair (BDAR).We present an Intelligent Battlefield Damage Assessment System (IBDAS) based on multi-agent system technology. We first establish the system framework, and then study the interior structure and workflow of a problem allocation agent. The result shows that, there are many advantages to resolve the problem of battlefield damage assessment by applying multi-agent system technology, and it will bring significant military benefit.

  15. Tissue quality assessment using a novel direct elasticity assessment device (the E-finger: a cadaveric study of prostatectomy dissection.

    Directory of Open Access Journals (Sweden)

    Daniel W Good

    Full Text Available Minimally invasive radical prostatectomy (RP (robotic and laparoscopic, have brought improvements in the outcomes of RP due to improved views and increased degrees of freedom of surgical devices. Robotic and laparoscopic surgeries do not incorporate haptic feedback, which may result in complications secondary to inadequate tissue dissection (causing positive surgical margins, rhabdosphincter damage, etc. We developed a micro-engineered device (6 mm2 sized [E-finger] capable of quantitative elasticity assessment, with amplitude ratio, mean ratio and phase lag representing this. The aim was to assess the utility of the device in differentiating peri-prostatic tissue types in order to guide prostate dissection.Two embalmed and 2 fresh frozen cadavers were used in the study. Baseline elasticity values were assessed in bladder, prostate and rhabdosphincter of pre-dissected embalmed cadavers using the micro-engineered device. A measurement grid was created to span from the bladder, across the prostate and onto the rhabdosphincter of fresh frozen cadavers to enable a systematic quantitative elasticity assessment of the entire area by 2 independent assessors. Tissue was sectioned along each row of elasticity measurement points, and stained with haematoxylin and eosin (H&E. Image analysis was performed with Image Pro Premier to determine the histology at each measurement point.Statistically significant differences in elasticity were identified between bladder, prostate and sphincter in both embalmed and fresh frozen cadavers (p = < 0.001. Intra-class correlation (ICC reliability tests showed good reliability (average ICC = 0.851. Sensitivity and specificity for tissue identification was 77% and 70% respectively to a resolution of 6 mm2.This cadaveric study has evaluated the ability of our elasticity assessment device to differentiate bladder, prostate and rhabdosphincter to a resolution of 6 mm2. The results provide useful data for which to continue to

  16. A study on assessment methodology of surveillance test interval and allowed outage time

    Energy Technology Data Exchange (ETDEWEB)

    Che, Moo Seong; Cheong, Chang Hyeon; Lee, Byeong Cheol [Seoul Nationl Univ., Seoul (Korea, Republic of)] (and others)


    The objectives of this study is the development of methodology by which assessing the optimizes Surveillance Test Interval(STI) and Allowed Outage Time(AOT) using PSA method that can supplement the current deterministic methods and the improvement of Korea nuclear power plants safety. In the first year of this study, the survey about the assessment methodologies, modeling and results performed by domestic and international researches is performed as the basic step before developing the assessment methodology of this study. The assessment methodology that supplement the revealed problems in many other studies is presented and the application of new methodology into the example system assures the feasibility of this method.

  17. The study of the life cycle of technology assessment model

    Institute of Scientific and Technical Information of China (English)

    SHEN Yu-Zhi; HUANG Xun-jiang


    The life cycle of technology is one of the most important indexes to weigh up the risk of the investment to neo-tech. There are so many uncertainties because it is conditioned by a lot of factors, we can not make a rational forecasting by traditional assessment method. So this paper gives a conprehensive consideration to the factors that influence production and makes some modification to production function, and establishes the life cycle of technology assessmet model by the method of fuzzy mathematics. So it quantifies the risk of investment. We can take it as one foundational index for the decision making of the investment.

  18. Site-Specific ecological risk assessment. Case-study 2

    DEFF Research Database (Denmark)

    Jensen, John

    “Development of a decision support system for sustainable management of contaminated land by linking bioavailability, ecological risk and ground water pollution of organic pollutants”or in short “LIBERATION”. The presentation includes examples on how to scale and integrate the results from various scientific......The decision supporting and integrating assessment tool, TRIAD, is used site-specific on PAH- and heavy metal contaminated sites in Denmark. The various aspects of the TRIAD approach are used on a set of chemistry-, ecotoxicology- and ecology related data collected among others in the EU project...

  19. Assessing Evaluation Studies: The Case of Bilingual Education Strategies. (United States)

    Meyer, Michael M., Ed.; Fienberg, Stephen E., Ed.

    Results of a National Research Council review of two major bilingual education studies are presented. The two studies were a national longitudinal study of the effectiveness of instruction of limited-English-proficient students and a study comparing three bilingual education program types (immersion, early exit, and late exit). The report contains…

  20. Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport. (United States)

    Siedler, Solvej; Bringer, Stephanie; Blank, Lars M; Bott, Michael


    Optimization of yields and productivities in reductive whole-cell biotransformations is an important issue for the industrial application of such processes. In a recent study with Escherichia coli, we analyzed the reduction of the prochiral β-ketoester methyl acetoacetate by an R-specific alcohol dehydrogenase (ADH) to the chiral hydroxy ester (R)-methyl 3-hydroxybutyrate (MHB) using glucose as substrate for the generation of NADPH. Deletion of the phosphofructokinase gene pfkA almost doubled the yield to 4.8 mol MHB per mole of glucose, and it was assumed that this effect was due to a partial cyclization of the pentose phosphate pathway (PPP). Here, this partial cyclization was confirmed by (13)C metabolic flux analysis, which revealed a negative net flux from glucose 6-phosphate to fructose 6-phosphate catalyzed by phosphoglucose isomerase. For further process optimization, the genes encoding the glucose facilitator (glf) and glucokinase (glk) of Zymomonas mobilis were overexpressed in recombinant E. coli strains carrying ADH and deletions of either pgi (phosphoglucose isomerase), or pfkA, or pfkA plus pfkB. In all cases, the glucose uptake rate was increased (30-47%), and for strains Δpgi and ΔpfkA also, the specific MHB production rate was increased by 15% and 20%, respectively. The yield of the latter two strains slightly dropped by 11% and 6%, but was still 73% and 132% higher compared to the reference strain with intact pgi and pfkA genes and expressing glf and glk. Thus, metabolic engineering strategies are presented for improving yield and rate of reductive redox biocatalysis by partial cyclization of the PPP and by increasing glucose uptake, respectively.

  1. Strategic Assessment Model and Its Application:a Case Study

    Institute of Scientific and Technical Information of China (English)

    ZHU Xiu-wen; CAO Meng-xia; ZHU Ning; ZUO M1ng-j1an


    Accurate and effective assessment of strategic alternatives of an organization directly affects the decision-making and execution of its development strategy. In evaluation of strategic alternatives, relevant elements from both internal and external environments of an organization must be considered. In this paper we use strategic assessment model to evaluate strategic alternatives of an air-conditioning company. Strategic objectives and alternatives of the company are developed through analysis of the competitive environment,key competitors and internal conditions. The environment factors are classified into internal, task, and general opportunities and threats. Analytical hierarchy process, subjective probabilities, entropy concept,and utility theory are used to enhance decision-maker's ability in evaluating strategic alternatives. The evaluation results show that the most effective strategic alternative for the company is to reduce types of products, concentrate its effort on producing window-type and cupboard-type air-conditioners, enlarge the production scale, and pre-empt the market. The company has made great progress by implementing this alternative. We conclude that SAM is an appropriate tool for evaluating strategic alternatives.

  2. Assessment of SPM in perfusion brain SPECT studies. A numerical simulation study using bootstrap resampling methods. (United States)

    Pareto, Deborah; Aguiar, Pablo; Pavía, Javier; Gispert, Juan Domingo; Cot, Albert; Falcón, Carles; Benabarre, Antoni; Lomeña, Francisco; Vieta, Eduard; Ros, Domènec


    Statistical parametric mapping (SPM) has become the technique of choice to statistically evaluate positron emission tomography (PET), functional magnetic resonance imaging (fMRI), and single photon emission computed tomography (SPECT) functional brain studies. Nevertheless, only a few methodological studies have been carried out to assess the performance of SPM in SPECT. The aim of this paper was to study the performance of SPM in detecting changes in regional cerebral blood flow (rCBF) in hypo- and hyperperfused areas in brain SPECT studies. The paper seeks to determine the relationship between the group size and the rCBF changes, and the influence of the correction for degradations. The assessment was carried out using simulated brain SPECT studies. Projections were obtained with Monte Carlo techniques, and a fan-beam collimator was considered in the simulation process. Reconstruction was performed by using the ordered subsets expectation maximization (OSEM) algorithm with and without compensation for attenuation, scattering, and spatial variant collimator response. Significance probability maps were obtained with SPM2 by using a one-tailed two-sample t-test. A bootstrap resampling approach was used to determine the sample size for SPM to detect the between-group differences. Our findings show that the correction for degradations results in a diminution of the sample size, which is more significant for small regions and low-activation factors. Differences in sample size were found between hypo- and hyperperfusion. These differences were larger for small regions and low-activation factors, and when no corrections were included in the reconstruction algorithm.

  3. Team Objective Structured Bedside Assessment (TOSBA) as formative assessment in undergraduate Obstetrics and Gynaecology: a cohort study.

    LENUS (Irish Health Repository)

    Deane, Richard P


    Team Objective Structured Bedside Assessment (TOSBA) is a learning approach in which a team of medical students undertake a set of structured clinical tasks with real patients in order to reach a diagnosis and formulate a management plan and receive immediate feedback on their performance from a facilitator. TOSBA was introduced as formative assessment to an 8-week undergraduate teaching programme in Obstetrics and Gynaecology (O&G) in 2013\\/14. Each student completed 5 TOSBA sessions during the rotation. The aim of the study was to evaluate TOSBA as a teaching method to provide formative assessment for medical students during their clinical rotation. The research questions were: Does TOSBA improve clinical, communication and\\/or reasoning skills? Does TOSBA provide quality feedback?

  4. 1982 Aleutian Islands salmon stock assessment study: Legislative report (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a comprehensive research study of the Aleutian Islands salmon resources in 1982. The study encompassed the area west of Unimak Pass to Attu...

  5. Risk of falls in Brazilian elders with and without low back pain assessed using the Physiological Profile Assessment: BACE study

    Directory of Open Access Journals (Sweden)

    Nayza M. B. Rosa

    Full Text Available ABSTRACT Background Low back pain (LBP is a common musculoskeletal condition among elders and is associated with falls. However, the underlying biological risk factors for falling among elders with LBP has been poorly investigated. The Physiological Profile Assessment (PPA is a validated fall-risk assessment tool that involves the direct assessment of sensorimotor abilities and may contribute to the understanding of risk factors for falls among elders with LBP. Objective To assess fall risk using the PPA in elders with and without LBP. Method This is an observational, comparative, cross-sectional study with elders aged ≥65 years. The present study was conducted with a subsample of participants from the Back Complaints in the Elders (BACE - Brazil study. Fall risk was assessed using the PPA, which contains five tests: visual contrast sensitivity, hand reaction time, quadriceps strength, lower limb proprioception, and postural sway. Results Study participants included 104 individuals with average age of 72.3 (SD=4.0 years, divided into two groups: GI 52 participants with LBP; GII 52 participants without LBP. The participants with LBP had a significantly higher fall risk (1.10 95% CI 0.72 to 1.48, greater postural sway (49.78 95% CI 13.54 to 86.01, longer reaction time (58.95 95% CI 33.24 to 84.65, and lower quadriceps strength (–4.42 95% CI –8.24 to –0.59 compared to asymptomatic participants. There was no significant difference for vision and proprioception tests between LBP and non-LBP participants. Conclusion Elders with LBP have greater risk for falls than those without LBP. Our results suggest fall-risk screening may be sensible in elders with LBP.


    Directory of Open Access Journals (Sweden)

    Hassan DARVISH


    Full Text Available Evolution of safety climate used as a practical means has determined and assessed potential problems relevant to safety issues in an organization and can be used in individuals’ performance and work efficiency and decreasing rate of incidents ;as well as; guidance to provide safety organization policy and comparison of safety performance in different organizations. The study wants to determine and prepare safety climate profile and application of its results in improving safety situation. In this study, applied tools presented by Loughborough University are used to evaluate safety climate in one of steel industries and data is collected through questionnaire, group discussions or purposeful interviews and observations, and safety climate score was obtained in 17 scopes. Calculating the score of each safety climate domain and preparing the profile indicated there is the average rate (4.89 2 in the safety climate of the industry.

  7. Comparative study of probabilistic methodologies for small signal stability assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rueda, J.L.; Colome, D.G. [Universidad Nacional de San Juan (IEE-UNSJ), San Juan (Argentina). Inst. de Energia Electrica], Emails:,


    Traditional deterministic approaches for small signal stability assessment (SSSA) are unable to properly reflect the existing uncertainties in real power systems. Hence, the probabilistic analysis of small signal stability (SSS) is attracting more attention by power system engineers. This paper discusses and compares two probabilistic methodologies for SSSA, which are based on the two point estimation method and the so-called Monte Carlo method, respectively. The comparisons are based on the results obtained for several power systems of different sizes and with different SSS performance. It is demonstrated that although with an analytical approach the amount of computation of probabilistic SSSA can be reduced, the different degrees of approximations that are adopted, lead to deceptive results. Conversely, Monte Carlo based probabilistic SSSA can be carried out with reasonable computational effort while holding satisfactory estimation precision. (author)

  8. Assessment of polymorphic metabolite data in bioavailability/bioequivalence studies - considerations and challenges

    Directory of Open Access Journals (Sweden)

    Nuggehally R Srinivas


    Full Text Available Bioavailability (BA/ bioequivalence (BE studies are the cornerstone for the approval of generic drugs. While BA/BE assessment involving the pharmacokinetic data of the parent compound has been routinely performed, the introduction of the assessment of metabolite(s data, alone or in addition to parent compound, has also emerged. In this context, the assessment of BA/BE of metabolite(s may pose additional complexities and challenges, if the metabolic pathway is under the influence of a polymorphic enzyme. This communication provides brief perspectives on the challenges and study design considerations for the assessment of polymorphic metabolite in BA/BE studies.

  9. The National Study of Water Management during Drought: A Research Assessment (United States)


    Regional Water Sources and Needs Study: Example Design of Activities 132 Figure V-2 Regional Drought Assessment Study Design 146 Figure V-3...Water Plan--Section: Emergency Services Drought Management. Division Nebraska University of Nebraska Yes. Drought Assessment and Response Plan. Nevada...survey was conducted by D. A. Wilhite entitled Drought Assessment Response Activities of State Governments to determine the impacts and actions taken

  10. A Study on the Correlation between Second Language Learning Motiva-tion and Formative Assessment

    Institute of Scientific and Technical Information of China (English)

    何爱玲; 杨坚


    This paper explores the relationship between motivation and assessment and find out the assessment strategies which could motivate students better in L2 learning based on the data and responses collected from 30 non-English majors in a regional university. The data and responses revealed that formative assessment could motivate students better, especially during the process of English learning. It also revealed some problems existing in the assessment strategies implemented in this study, such as the im-partiality of peer-assessment and the poor efficiency of group work.

  11. Southeast Florida Sediment Assessment and Needs Determination (SAND) Study (United States)


    Study team. Linda Lillycrop is the Program Manager of the Regional Sediment Management Program (RSM), Coastal Engineering Branch (HNC), and findings were presented to the SAND Study Team, who requested a third-party peer review be conducted. Coastal Planning and Engineering...feasible for beach nourishment . Carbonate-content testing of vibracore samples (SAND Study vibracores and historic data when available) indicated

  12. A Study of STEM Assessments in Engineering, Science, and Mathematics for Elementary and Middle School Students (United States)

    Harwell, Michael; Moreno, Mario; Phillips, Alison; Guzey, S. Selcen; Moore, Tamara J.; Roehrig, Gillian H.


    The purpose of this study was to develop, scale, and validate assessments in engineering, science, and mathematics with grade appropriate items that were sensitive to the curriculum developed by teachers. The use of item response theory to assess item functioning was a focus of the study. The work is part of a larger project focused on increasing…

  13. The Use of Analytic Rubric in the Assessment of Writing Performance--Inter-Rater Concordance Study (United States)

    Beyreli, Latif; Ari, Gokhan


    In this study, the purpose was to determine whether there was concordance among raters in the assessment of the writing performance using analytic rubric; furthermore, factors affecting the assessment process were examined. The analytic rubric used in the study consists of three sections and ten properties: External structure (format, spelling and…

  14. Evaluation on the Feasibility of Using Ultrasonic Testing of Reactor Pressure Vessel Welds for Assessing Flaw Density/Distribution per 10 CFR 50.61a, Alternate Fracture Toughness Requirements for Protection Against Pressurized Thermal Shock

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Edmund J.; Anderson, Michael T.


    This technical letter report provides the status of an assessment undertaken by PNNL at the request of the NRC to verify the capability of periodic ASME-required volumetric examinations of reactor vessels to characterize the density and distribution of flaws of interest for applying §50.61a on a plant-by-plant basis. The PTS rule, described in the Code of Federal Regulations, Title 10, Section 50.61 (§50.61), "Fracture Toughness Requirements for Protection against Pressurized Thermal Shock Events," establishes screening criteria to ensure that the potential for a reactor vessel to fail due to a PTS event is deemed to be acceptably low. Recently, the NRC completed a research program that concluded that the risk of through-wall cracking due to a PTS event is much lower than previously estimated. The NRC subsequently developed and promulgated an alternate PTS rule, §50.61a, that can be implemented by PWR licensees. The §50.61a rule differs from §50.61 in that it requires licensees who choose to follow this alternate method to analyze the results from periodic volumetric examinations required by the ASME Code, Section XI, Rules for Inservice Inspection (ISI) of Nuclear Power Plants.

  15. Assessing Medication Effects in the MTA Study Using Neuropsychological Outcomes (United States)

    Epstein, Jeffery N.; Conners, C. Keith; Hervey, Aaron S.; Tonev, Simon T.; Arnold, L. Eugene; Abikoff, Howard B.; Elliott, Glen; Greenhill, Laurence L.; Hechtman, Lily; Hoagwood, Kimberly; Hinshaw, Stephen P.; Hoza, Betsy; Jensen, Peter S.; March, John S.; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen; Vitiello, Benedetto; Wigal, Timothy


    Background: While studies have increasingly investigated deficits in reaction time (RT) and RT variability in children with attention deficit/hyperactivity disorder (ADHD), few studies have examined the effects of stimulant medication on these important neuropsychological outcome measures. Methods: 316 children who participated in the Multimodal…

  16. 2002 progress report and public health assessment study

    Energy Technology Data Exchange (ETDEWEB)



    Clean Air Hamilton focuses on improving air quality in the City by providing advice to City Council. The actions and activities of Clean Air Hamilton directly benefit residents. The activities relate to natural areas and corridors; reducing and managing waste; consuming less energy; changing our modes of transportation; land use issues in urban areas; and, personal health and well-being. The report includes an assessment of human health impacts caused by air pollution in Hamilton. It uses the most recent science and Hamilton air quality data as a basis. The results indicate that approximately 100 people die prematurely each year in Hamilton, while approximately 620 people require admission to hospitals for respiratory and cardiovascular problems related to exposure to pollutants. The second Upwind Downwind Conference was held in February 2002, sponsored by Clean Air Hamilton. All three levels of government view Clean Air Hamilton as a success. The City of Hamilton was awarded the prestigious 2000 Dubai International Award for Best Practices in Improving Living Environment as a result of Clean Air Hamilton's community process in local air quality improvement. 47 refs., tabs., 1 fig.

  17. Transgender health: findings from two needs assessment studies in Philadelphia. (United States)

    Kenagy, Gretchen P


    HIV/AIDS, suicide, violence, and barriers to health care access among transgender people were explored using two needs assessment surveys conducted in Philadelphia in 1997. A total of 182 people responded to a face-to-face interview or self-administered mail survey: 113 male-to-female individuals and 69 female-to-male individuals. About three-fifths of respondents had engaged in unprotected sexual activity during the past 12 months. The risk for HIV infection from unprotected sex was significantly higher among respondents of color than among white respondents. About one-third (30.1 percent) of respondents had attempted suicide. More than half of respondents had been forced to have sex, 56.3 percent had experienced violence in their homes, and 51.3 percent had been physically abused. Twenty-six percent of respondents had been denied medical care because they were transgender. These findings suggest that prevention services that specifically address HIV/AIDS, suicide, and violence among transgender people are urgently needed.

  18. Foster care assessment: An exploratory study of the placement assessment process in Flanders and the Netherlands

    NARCIS (Netherlands)

    Vanderfaeillie, J.; Damen, H.R.; Pijnenburg, H.M.P.H.M.; Bergh, P.M. van den; Holen, F. van


    Family foster care placement decision-making has a weak scientific underpinning. The identification of clusters of foster children (groups of foster children with similar characteristics) can help improve decision quality. In this study, we investigated if foster children could indeed be clustered,

  19. Relations between student perceptions of assessment authenticity, study approaches and learning outcome.

    NARCIS (Netherlands)

    Gulikers, Judith; Bastiaens, Theo; Kirschner, Paul A.; Kester, Liesbeth


    Gulikers, J. T. M., Bastiaens, Th. J., Kirschner, P. A., & Kester, L. (2006). Relations between student perceptions of assessment authenticity, study approaches and learning outcome. Studies in Educational Evaluation, 32 , 381-400

  20. A social work study for assessment of entrepreneurs' personal characteristics

    Directory of Open Access Journals (Sweden)

    Ahmad Ahmadkhani


    Full Text Available The personality of an entrepreneur plays an important role on the success of creating new ideas. There are different characteristics such as courage, hardness, braveness, which could help an entrepreneur reach his/her goals. In this paper, we present an empirical study to learn more about students who are supposed to act as entrepreneur to create jobs in different fields of accounting, computer science, mechanical engineering, etc. In this paper, There are seven aspects of accepting reasonable risk, locus of control, the need for success, mental health conditions, being pragmatic, tolerating ambiguity, dreaming and the sense of challenging in our study to measure the level of entrepreneurship. We implement ANOVA test to measure different entrepreneurship characteristics of students who study in various educational fields. The case study is associated with Sama private university located in city of Zanjan/Iran. The results indicate that there are not meaningful differences among pairwise comparison of many engineering fields.

  1. Assessing Holland Types on the Internet: A Comparative Study (United States)

    Miller, Mark J.; Cowger, Ernest, Jr.; Young, Tony; Tobacyk, Jerome; Sheets, Tillman; Loftus, Christina


    This study examined the degree of similarity between scores on the Self-Directed Search and an online instrument measuring Holland types. A relatively high congruency score was found between the two measures. Implications for career counselors are discussed.

  2. Mississippi River Hydrodynamic and Delta Management Study (MRHDM) - Geomorphic Assessment (United States)


    Biedenharn Group conducted this study from April 2012 to February 2014. The principal investigators for this study were Charlie Little of the Parker and Troutman (1989) proposed that the parameter θ2 may have a physically significant interpretation in terms of sediment supply, as...Vicksburg, MS: U.S. Army Corps of Engineers, Lower Mississippi Valley Division. Parker , R., and B. Troutman. 1989. Frequency distribution for

  3. Improving Biomarker Development and Assessment: Standards for Study Design

    Institute of Scientific and Technical Information of China (English)

    Ziding FENG


    Background: The Early Detection Research Network (EDRN), NCI funded and investigator driven, has the mission to evaluate biomarkers for their clinical utilities in cancer risk prediction, diagnosis, early detection, and prognosis. Abundant cancer biomarkers reported in literature yet few are used in clinics. Therefore, the emphasis of the EDRN is biomarker validation. Although schema for a phased approach to development exists and guidelines are available for study reporting, a coherent and comprehensive set of guideline for a definitive biomarker validation study design have not been delineated.Methods: We proposed PROBE study design, Prospective specimen collec-tion and Retrospective Blinded Evaluation, for pivotal definitive evaluation of the accuracy of a classification biomarker. A detailed formulation of all aspects of the design is provided. Four tables itemize aspects that relate to (i) the Clinical Context; (ii) Performance Criteria; (iii) the Biomarker test; and (iv) Study power and termination. Alternative designs and strategies were contrasted to illustrate the merit of PROBE design.Results: The ideas are applied to studies of biomarkers the intended use of which is for disease diagnosis, screening, or prognosis. Two EDRN valida-tion studies (breast cancer and prostate cancer) were used as examples to elucidate PROBE design.Conclusion: Common biases that pervade the biomarker research literaturewould be eliminated if these rigorous standards were followed closely. We urge the adoption of the design as standard of practice for pivotal evaluation of the classification accuracy ofbiomarkers.

  4. How to scientifically assess a restoration project: a case study (United States)

    Alvarez de Buergo, M.; Fort, R.; Freire, D. M.; Lopez-Arce, P.; Vazquez-Calvo, C.


    Commonly, it is said that there is lack of communication among scientists, conservators, restorers, project managers and architects. But sometimes this communication flows, and we can find enormous benefits from and for all the participating agents. This is the case we present in this work, in which technical agents in charge of the restoration of a building, asked for some scientific advice to perform the restoration of a heritage building. The results were successful and fantastic for both of them, in terms of one part asking for consultation and the other answering to the demands and resolving real problems. This is the case of a marvellous Renaissance building (Medinaceli Dukes palace, 15th-16th centuries) in the central area of Spain (Cogolludo, Guadalajara). Focused on the restoration project, we were asked for consultancy on how to solve matters like the assessment of the already fixed in project cleaning method for the stone façades, the efficacy and durability methods for some conservation products to be applied, the presence or not of a patina on the stone; the viability of using some restoration mortars, and the origin of some efflorescences that came out just after placed in the building a restoration rendering mortar. Responses to these matters were answered by performing tests both in the lab and on site in the building. The efficiency and effects on stone of the blasting cleaning method was assessed by first analysing the nature and thickness of the surface deposits to be removed (SEM-EDS analyses); secondly, roughness and colour measurements were performed, and thirdly, SEM-EDS analyses were carried out again to determine whether the cleaning method was able to remove part of the surface deposits, completely, or even part of the stone substrate. Some conservation products were tested on stone specimens, both their efficacy and their durability, concluding that it was better not to apply any of them. A patina was found on the stone façade under SEM

  5. Looking at the Mirror: A Self-Study of Science Teacher Educators' PCK for Teaching Teachers (United States)

    Demirdögen, Betül; Aydin, Sevgi; Tarkin, Aysegül


    In this self-study, we aimed to delve into how re-designing and teaching re-designed practicum course offered to pre-service teachers (PTs) enriched our, as science teacher educators, development of pedagogical content knowledge (PCK) for teaching science teachers. This self-study was conducted during a compulsory practicum course in which we…

  6. US country studies program: Support for climate change studies, national plans, and technology assessments

    Energy Technology Data Exchange (ETDEWEB)



    This paper describes the objectives of the next phase of the U.S. Country Studies Program which was launched in support of the Framework Convention on Climate Change (FCCC). The next phases of this program aim to: assist countries in preparing Climate Change Action plans; support technology assessments and development of technology initiatives; enhance exchange of information and expertise in support of FCCC. The program offers support for these processes in the form of handbooks which have been published to aid in preparing action plans, and to provide information on methane, forestry, and energy technologies. In addition an array of training workshops have been and are scheduled to offer hands on instruction to participants, expert advice is available from trained personnel, and modeling tools are available to aid in development of action plans.

  7. Geothermal reservoir assessment case study: Northern Dixie Valley, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Denton, J.M.; Bell, E.J.; Jodry, R.L.


    Two 1500 foot temperature gradient holes and two deep exploratory wells were drilled and tested. Hydrologic-hydrochemical, shallow temperature survey, structural-tectonic, petrologic alteration, and solid-sample geochemistry studies were completed. Eighteen miles of high resolution reflection seismic data were gathered over the area. The study indicates that a geothermal regime with temperatures greater than 400/sup 0/F may exist at a depth of approximately 7500' to 10,000' over an area more than ten miles in length.

  8. Clinical assessment of transthoracic echocardiography skills: a generalizability study

    DEFF Research Database (Denmark)

    Nielsen, Dorte Guldbrand; O'Neill, Lotte; Jensen, Signe


    were calculated for both the global rating and checklist scores, and finally dependability (phi) coefficients were also calculated for both outcomes in a D-study. Results For global rating scores, 66.6% of score variance can be ascribed to true differences in performance. For checklist scores...

  9. Genesis Solar Wind Collector Cleaning Assessment: 60366 Sample Case Study (United States)

    Goreva, Y. S.; Gonzalez, C. P.; Kuhlman, K. R.; Burnett, D. S.; Woolum, D.; Jurewicz, A. J.; Allton, J. H.; Rodriguez, M. C.; Burkett, P. J.


    In order to recognize, localize, characterize and remove particle and thin film surface contamination, a small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques [1-5]. Here we present preliminary results for sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C).

  10. Development of the gagging problem assessment : A pilot study

    NARCIS (Netherlands)

    van den Heuvell, G. F. E. C. van Linden; Ter Pelkwijk, B. J.; Stegenga, B.


    An accepted management strategy for gagging problems appears not to exist. A reliable and valid instrument is needed to develop an evidence based treatment for this clinical problem. The aim of this pilot study was to evaluate the reliability and validity of a newly developed measurement tool for de

  11. Assessment of vascular and endothelial dysfunction in nutritional studies. (United States)

    Ray, S; Miglio, C; Eden, T; Del Rio, D


    Vascular and endothelial dysfunction (VED) is emerging as a potential set of early markers of cardiovascular disease risk and tests for its measurement have been widely used in clinical research. The aim of this viewpoint is to describe and discuss the current usage of these measures in well-designed nutritional trials, using the potential relationship between fruit juice intake and VED as example. A search was conducted using the NHS evidence portal including studies published in English between January 1980 and October 2013. Only 10 suitable studies were selected, which investigated the effect of fruit juice intake on VED, among which 4 interventions used flow-mediated dilatation, 2 arterial stiffness, 2 a combination of arterial stiffness and flow-mediated dilatation, 2 carotid intimal media thickness and 1 iontophoresis with laser Doppler. Despite minimal effects reported on classical CVD markers, such as lipids, 8 out of the 10 identified studies reported an effect on endothelial function following juice consumption, indicating that VED tests can be effectively used in human dietary interventions to identify relationships between bioactive compounds from fruit and CVD risk. However, paucity of available data, scarcity of compound bioavailability and metabolism information, strong heterogeneity among experimental methodologies and a number of limitations to study designs, still limit the interpretation of the results obtained through these measures. Future, well-designed studies with greater attention to consider use of VED measures are needed to strengthen the utility of VED tests in nutrition research such as those investigating the impact of polyphenol-rich juices and CVD risk.

  12. Teachers’ Beliefs about Young EFL Learners’ Self-assessment: a Case Study of Macedonia

    Directory of Open Access Journals (Sweden)

    /Anžela Nikolovska


    Full Text Available The paper explores Macedonian primary EFL teachers’ attitudes, beliefs and practices regarding self-assessment of young learners (10-12 year-olds. The study surveyed primary EFL teachers (n=30 who teach English to 5th and 6th graders. The results indicated that vocabulary, grammar and reading were more often the focus of self-assessment tasks than the other areas of language learning. This, along with the finding that the receptive language skills were more frequently self-assessed than the productive skills has been attributed to the impact of the external exam. The most frequently used self-assessment techniques were can-do statements and check-lists. The perceived benefits and challenges of self-assessment have been found to be compatible with the findings of other studies. In spite of their positive attitudes towards learner self-assessment, the teachers expressed awareness of certain problems underlying its implementation as well as uncertainty about how to train learners to self-assess. In line with the conclusions, recommendations have been made regarding the need for greater emphasis on self-assessment of the neglected language areas (speaking and writing, the necessity of using a variety of self-assessment formats and the need for learner training in self-assessment from an early age.

  13. Students' and teachers' perceptions of clinical assessment program: A qualitative study in a PBL curriculum

    Directory of Open Access Journals (Sweden)

    van der Vleuten Cees


    Full Text Available Abstract Background "Examinations drive students' learning." This statement refers to what is assumed to be one of the strongest relationships in education. We explored in this research how and why students differ in their approaches to learning, how assessment affects deep learning, and which barriers stand in the way of good assessment and learning in the clinical years of a Problem Based Learning (PBL graduate entry medical curriculum. Findings Method: We conducted a qualitative, phenomenological study using semi-structured group interviews with students and semi-structured individual interviews with teachers and students. The transcripts were analyzed, and themes were identified. Setting: The research was conducted at the King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia from November 2007 to March 2008. Results: A total of 28 students participated in 7 focus group interviews. Semi-structured individual interviews were conducted with 12 teachers and 12 students. The analysis yielded four themes: summative assessment, formative assessment, continuous assessment of clinical attachments, and learning objectives. Conclusions The results of this study confirm that assessment affects students' perceptions of learning and how they learn. These effects are not uniformly positive. According to the students, the predominantly summative assessment program offers little inducement to engage in deep learning. They express a clear preference for formative assessment, which may foster a deeper approach to learning. Efforts to achieve more clinically relevant assessment with adequate balance between the various types of assessment are required. Research is needed to decide this balance.

  14. An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study

    Energy Technology Data Exchange (ETDEWEB)

    Euling, Susan Y., E-mail: [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Thompson, Chad M. [ToxStrategies, Inc., 23501 Cinco Ranch Blvd., Suite G265, Katy, TX 77494 (United States); Chiu, Weihsueh A. [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Benson, Robert [U.S. Environmental Protection Agency, Region 8, Mail code 8P-W, 1595 Wynkoop Street, Denver, CO 80202 (United States)


    An approach for evaluating and integrating genomic data in chemical risk assessment was developed based on the lessons learned from performing a case study for the chemical dibutyl phthalate. A case study prototype approach was first developed in accordance with EPA guidance and recommendations of the scientific community. Dibutyl phthalate (DBP) was selected for the case study exercise. The scoping phase of the dibutyl phthalate case study was conducted by considering the available DBP genomic data, taken together with the entire data set, for whether they could inform various risk assessment aspects, such as toxicodynamics, toxicokinetics, and dose–response. A description of weighing the available dibutyl phthalate data set for utility in risk assessment provides an example for considering genomic data for future chemical assessments. As a result of conducting the scoping process, two questions—Do the DBP toxicogenomic data inform 1) the mechanisms or modes of action?, and 2) the interspecies differences in toxicodynamics?—were selected to focus the case study exercise. Principles of the general approach include considering the genomics data in conjunction with all other data to determine their ability to inform the various qualitative and/or quantitative aspects of risk assessment, and evaluating the relationship between the available genomic and toxicity outcome data with respect to study comparability and phenotypic anchoring. Based on experience from the DBP case study, recommendations and a general approach for integrating genomic data in chemical assessment were developed to advance the broader effort to utilize 21st century data in risk assessment. - Highlights: • Performed DBP case study for integrating genomic data in risk assessment • Present approach for considering genomic data in chemical risk assessment • Present recommendations for use of genomic data in chemical risk assessment.



    Junaidi Mistar


    his study is to investigate whether self-assessment contains construct- irrelevant variances of gender and age, and whether self-assessment correlates with test scores. The data were collected from seventy-eight newly arrived international students at the English Lan­guage Center, Michigan State University, USA. Prior to class com­mencement, they were asked to self-assess their listening, speaking, and interactive skill. Then, a test of listening was administered; finally, they were assigned ...

  16. Assessing Landscape Ecological Risk in a Mining City: A Case Study in Liaoyuan City, China



    Landscape ecological risk assessment can effectively identify key elements for landscape sustainability, which directly improves human wellbeing. However, previous research has tended to apply risk probability, measured by overlaying landscape metrics to evaluate risk, generally lacking a quantitative assessment of loss and uncertainty of risk. This study, taking Liaoyuan City as a case area, explores landscape ecological risk assessment associated with mining cities, based on probability of ...

  17. Assessment of polymorphic metabolite data in bioavailability/bioequivalence studies - considerations and challenges


    Srinivas, Nuggehally R.


    Bioavailability (BA)/ bioequivalence (BE) studies are the cornerstone for the approval of generic drugs. While BA/BE assessment involving the pharmacokinetic data of the parent compound has been routinely performed, the introduction of the assessment of metabolite(s) data, alone or in addition to parent compound, has also emerged. In this context, the assessment of BA/BE of metabolite(s) may pose additional complexities and challenges, if the metabolic pathway is under the influence of a poly...

  18. Delayed-onset muscle soreness: a pilot study to assess analgesic study design features. (United States)

    Singla, Neil; Desjardins, Paul J; Cosca, Evelyn B; Parulan, Cherri; Arriaga, Anne; Poole, Kelly C; Batz, Dan M; Chang, Phoebe D


    Based on a thorough review of the available literature in the delayed-onset muscle soreness (DOMS) model, we identified multiple study design characteristics that are considered to be normative in acute pain research but have not been followed in a majority of published DOMS experiments. We designed an analgesic investigation using the DOMS model that both complied with current scientifically accepted standards for the conduct of analgesic studies and demonstrated reasonable assay sensitivity. This randomized, double-blind, placebo-controlled within-subject study compared the efficacy of topical diclofenac sodium 1% with a matching placebo in reducing pain associated with DOMS. After exercise, subjects reporting DOMS received topical diclofenac sodium gel 1% (DSG 1%) applied to one leg and placebo to the other every 6 hours for 48 hours. Pain intensity was assessed at rest, upon standing, and when walking in the 48 hours after initial drug application (T0). The primary end point was the reduction in pain intensity (SPID 24) on walking. Subjects receiving DSG 1% had less pain while walking compared with those receiving placebo at 24 hours (SPID 24 = 34.9 [22.9] and 23.6 [19.4], respectively; P = 0.032). This investigation used experimental techniques that have been vetted in the field of exercise physiology and superimposed techniques that are considered to be best practice in the field of analgesic research. Over time and with the help of colleagues in both fields of study, similar investigations will validate design features that impact the assay sensitivity of analgesic end points in DOMS models. In addition, the study confirmed the analgesic efficacy of topical DSG 1% over placebo in subjects experiencing DOMS.

  19. Assessment of different dyes used in leakage studies. (United States)

    Mente, Johannes; Ferk, Stephan; Dreyhaupt, Jens; Deckert, Andreas; Legner, Milos; Staehle, Hans Joerg


    The goal of this in vitro study was to identify the most suitable dye for endodontic dye leakage studies, which could be a further step towards standardisation. The root canals of 70 extracted, single-rooted human adult teeth were enlarged to apical size 50 using hand instruments. The teeth were divided into seven groups (n = 10 each), and all root canals were completely filled by injection with one of the following dyes: methylene blue 0.5% and 5%, blue ink, black ink, eosin 5%, basic fuchsin 0.5% and drawing ink. Transverse root sections from the coronal, middle and apical part of the roots were examined, and the percentage of the dentine penetrated by dye was evaluated by software-supported light microscopy. In addition, the range of particle size of drawing ink particles was evaluated. There were conspicuous differences in the relative dye penetration into the root dentine and the penetration behaviour in the different root sections (two-way ANOVA, both p < 0.0001). One dye (drawing ink) penetrated less into the root dentine compared with all the others (p <0.0001). The particle size of this agent (0.1-2 microm) corresponds best with the size range of a representative selection of 21 species of pathogenic endodontic bacteria. Compared to the other dyes tested, drawing ink appears to be superior for use in endodontic dye leakage studies. The penetration behaviour into the root dentine of all the other dyes tested might be one factor that limits the applicability of these dyes in dye leakage studies.

  20. Assessment of scientific research: a case-study of CERN

    Energy Technology Data Exchange (ETDEWEB)

    Martin, B.R.; Minchin, N.; Skea, J.; Peacock, T.; Crouch, D.; Irvine, J.


    The review aims to demonstrate that formal methods of evaluating research performance can play a valuable role in overcoming some of the problems with decision-making in basic science based on peer review. An approach which combines a number of research output indicators, including bibliometric measures derived from publication and citation analysis, is first outlined and then applied in a case study of the European Laboratory for Particle Physics, CERN, over the period 1961-1984.

  1. Epidemiological Assessments of Skin Outcomes in the Nurses’ Health Studies (United States)

    Li, Wen-Qing; Cho, Eunyoung; Weinstock, Martin A.; Mashfiq, Hasan


    Objectives. To review the contribution of the Nurses’ Health Studies (NHSs) to identifying epidemiological factors associated with multiple skin diseases, including skin cancer, psoriasis, and other inflammatory and autoimmune skin diseases. Methods. We carried out a narrative review of NHS articles published between 1976 and 2016. Results. The NHSs have identified environmental and lifestyle factors related to psoriasis, supporting obesity and smoking as psoriasis risk factors; associations between psoriasis and diabetes, myocardial infarction, and Crohn’s disease, supporting psoriasis as a systemic disorder; and associations of pigmentary traits, ultraviolet radiation, and lifestyle factors such as citrus consumption with risk of skin cancer. Genetic studies have identified novel genetic loci for skin pigmentation (e.g., IRF4, SLC24A4, NID1, and EDNRB) and skin cancer (e.g., TET2 and HERC2-OCA2). Work continues on highly prevalent but less studied skin conditions such as rosacea, acne, and atopic dermatitis. The NHS results have influenced public health policies on indoor tanning devices. Conclusions. The NHSs have provided invaluable resources on skin disease population science and contributed to the etiological understanding of multiple skin disorders. PMID:27459457

  2. Assessing Statistical Change Indices in Selected Social Work Intervention Research Studies (United States)

    Ham, Amanda D.; Huggins-Hoyt, Kimberly Y.; Pettus, Joelle


    Objectives: This study examined how evaluation and intervention research (IR) studies assessed statistical change to ascertain effectiveness. Methods: Studies from six core social work journals (2009-2013) were reviewed (N = 1,380). Fifty-two evaluation (n= 27) and intervention (n = 25) studies met the inclusion criteria. These studies were…

  3. A Comparative Study on Emerging Electric Vehicle Technology Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Ford, Jonathan [Sentech, Inc.; Khowailed, Gannate [Sentech, Inc.; Blackburn, Julia [Sentech, Inc.; Sikes, Karen [Sentech, Inc.


    Numerous organizations have published reports in recent years that investigate the ever changing world of electric vehicle (EV) technologies and their potential effects on society. Specifically, projections have been made on greenhouse gas (GHG) emissions associated with these vehicles and how they compare to conventional vehicles or hybrid electric vehicles (HEVs). Similar projections have been made on the volumes of oil that these vehicles can displace by consuming large amounts of grid electricity instead of petroleum-based fuels. Finally, the projected rate that these new vehicle fleets will enter the market varies significantly among organizations. New ideas, technologies, and possibilities are introduced often, and projected values are likely to be refined as industry announcements continue to be made. As a result, over time, a multitude of projections for GHG emissions, oil displacement, and market penetration associated with various EV technologies has resulted in a wide range of possible future outcomes. This leaves the reader with two key questions: (1) Why does such a collective range in projected values exist in these reports? (2) What assumptions have the greatest impact on the outcomes presented in these reports? Since it is impractical for an average reader to review and interpret all the various vehicle technology reports published to date, Sentech Inc. and the Oak Ridge National Laboratory have conducted a comparative study to make these interpretations. The primary objective of this comparative study is to present a snapshot of all major projections made on GHG emissions, oil displacement, or market penetration rates of EV technologies. From the extensive data found in relevant publications, the key assumptions that drive each report's analysis are identified and 'apples-to-apples' comparisons between all major report conclusions are attempted. The general approach that was taken in this comparative study is comprised of six primary

  4. Varfarin in the complex treatment of antiphospholipid syndrome: preliminary results

    Directory of Open Access Journals (Sweden)

    T M Reshetnyak


    Full Text Available Objective. To assess efficacy and tolerance of varfarin in prophylaxis and therapy of thrombotic complications in patients with antiphospholipid syndrome (APS. Methods. 20 pts with APS (5 male and 15 female received varfarin during a year. 8 of them had primary APS (PAPS and 12 -systemic lupus erythematosus with APS (SLE+APS. 2 other pts (I with SLE+APS and I with PAPS received varfarin during the last 4 years. Nobody from 9 pts with PAPS received corticosteroids (CS. In SLE+APS pts CS dose varied from 4 to 20 mg/day and was not increased during follow up. During the study prothrombine time (PT was examined with thromboplastin ( manufactured by Renam having international sensitivity index 1,2 and international normalization relation (INR. Depending on treatment scheme APS pts were divided into 3 groups. Group 1 included 8 pts with INR<2,0, Group 2-7 with INR >3,0, group 3 - 7 pts with INR<2,0 receiving as additional treatment thrombo ASS 100 mg/day and vasonit from 600 to 1200 mg/day. Results. Two pts with INR = 1,8 had thrombosis recurrence (due to leg thrombophlebitis. There were no recurrences in other groups. 2 from 22 pts had "large" bleedings. "Small" bleedings episodes were noted in 7 from 22 pts. Largely that were subcutaneous bleedings (in 4 pts no more than 5 cm of size. Two pts receiving varfarin with INR 1,8 and 2,4 had renal colic. Conclusion. Our preliminary results prove the necessity of inclusion of varfarin in the treatment of pts with APS and thrombosis but intensive anticoagulant effect is not always desired.

  5. Assessment of Satellite Images for Soil Salinity Studies

    Directory of Open Access Journals (Sweden)

    S.H. Sanaeinejad


    Full Text Available Soil salinity is one of the main environmental problems affecting extensive area in the world. There are some problems with traditional data collection methods for soil studies. Using the new methods and techniques such as remote sensing could overcome most of these problems. However using these data in areas with uncommon usages needed some researches to find the best calibration between the data and real situations in soil. This research was carried out using Landsat satellite images in Neyshabour area, North East of Iran. In order to prepare suitable learning samples for the image processing in this study, 300 locations were randomly selected in the area, among which 273 locations were finally selected as suitable surface soil samples. All samples were moved to laboratory and their electrical conductivity was measured. Six reflective bands of ETM+ satellite images taken from the study area in 2002 were used for the image processing analysis. Classification of different soil salinities was carried out using common algorithms of image classification based on the best composition bands and using statistical methods between soil salinity variables and digital numbers of the images to represent a suitable method. the research results showed that the reflective bands 7, 3, 4 and 1 are the best band composition for preparing the color composite images and for the classification of the salinity in this area. The highest coefficient of determination was R2=0.311 and R2=0.44 for saline and non-saline soil respectively using band 2 and 3 of the images at 5% significant level. Based on the results, it can be concluded that the potential of ETM+ images for delineation and identification of different soil salinity are limited.


    Energy Technology Data Exchange (ETDEWEB)

    Halverson, N


    In February 2000, the United States Environmental Protection Agency (EPA) Region 4 issued a proposed Total Maximum Daily Load (TMDL) for total mercury in the middle and lower Savannah River. The initial TMDL, which would have imposed a 1 ng/l mercury limit for discharges to the middle/lower Savannah River, was revised to 2.8 ng/l in the final TMDL released in February 2001. The TMDL was intended to protect people from the consumption of contaminated fish, which is the major route of mercury exposure to humans. The most bioaccumulative form of mercury is methylmercury, which is produced in aquatic environments by the action of microorganisms on inorganic mercury. Because of the environmental and economic significance of the mercury discharge limits that would have been imposed by the TMDL, the Savannah River Site (SRS) initiated several studies concerning: (1) mercury in SRS discharges, SRS streams and the Savannah River, (2) mercury bioaccumulation factors for Savannah River fish, (3) the use of clams to monitor the influence of mercury from tributary streams on biota in the Savannah River, and (4) mercury in rainwater falling on the SRS. The results of these studies are presented in detail in this report. The first study documented the occurrence, distribution and variation of total and methylmercury at SRS industrial outfalls, principal SRS streams and the Savannah River where it forms the border with the SRS. All of the analyses were performed using the EPA Method 1630/31 ultra low-level and contaminant-free techniques for measuring total and methylmercury. Total mercury at National Pollutant Discharge Elimination System (NPDES) outfalls ranged from 0.31-604 ng/l with a mean of 8.71 ng/l. Mercury-contaminated groundwater was the source for outfalls with significantly elevated mercury concentrations. Total mercury in SRS streams ranged from 0.95-15.7 ng/l. Mean total mercury levels in the streams varied from 2.39 ng/l in Pen Branch to 5.26 ng/l in Tims Branch

  7. Aspects of brittle failure assessment for RPV

    Energy Technology Data Exchange (ETDEWEB)

    Zecha, H.; Hermann, T.; Hienstorfer, W. [TUeV SUeD Energietechnik GmbH Baden-Wuerttemberg, Filderstadt (Germany); Schuler, X. [Materialpruefungsanstalt, Univ. Stuttgart (Germany)


    This paper describes the process of pressurized thermal shock analysis (PTS) and brittle failure assessment for the reactor pressure vessel (RPV) of the nuclear power plants NECKAR I/II. The thermo-hydraulic part of the assessment provides the boundary conditions for the fracture mechanics analysis. In addition to the one dimensional thermo-hydraulic simulations CFD, analyses were carried out for selected transients. An extensive evaluation of material properties is necessary to provide the input data for a reliable fracture mechanics assessment. For the core weld and the flange weld it has shown that brittle crack initiation can be precluded for all considered load cases. For the cold and hot leg nozzle detailed linear-elastic and elasticplastic Finite Element Analyses (FEA) are performed to verify the integrity of the RPV. (orig.)

  8. Assessment of domestic water quality: case study, Beirut, Lebanon. (United States)

    Korfali, Samira Ibrahim; Jurdi, Mey


    In urban cities, the environmental services are the responsibility of the public sector, where piped water supply is the norm for urban household. Likewise, in Beirut City (capital of Lebanon) official water authorities are the main supplier of domestic water through a network of piping system that leaks in many areas. Beirut City and its suburbs are overpopulated since it is the residence of 1/3 of the Lebanese citizens. Thus, Beirut suffers deficiency in meeting its water demand. Water rationing, as a remedial action, is firmly established since four decades by the Lebanese Water Authorities. Consumers resorted then to private wells to supplement their domestic water needs. Consequently, household water quality is influenced by external factors relating to well water characteristics and internal factors depending on the types of the pipes of the distribution network and cross connections to sewer pipes. These factors could result in chemical and microbial contamination of drinking water. The objective of this study is to investigate domestic water quality variation in Beirut City emerging form the aforementioned factors. The presented work encircles a typical case study of Beirut City (Ras Beirut). Results showed deterioration pattern in domestic water quality. The predicted metal species and scales within the water pipes of distribution network depended on water pH, hardness, sulfate, chloride, and iron. The corrosion of iron pipes mainly depended on Mg hardness.

  9. Environmental Assessment of a Waste Incineration Tax. Case Study and Evaluation of a Framework for Strategic Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerklund, Anna; Johansson, Jessica [Swedish Defence Research Agency, Stockholm (Sweden); Nilsson, Maans [Stockholm Environment Inst., Stockholm (Sweden); Eldh, Peter; Finnveden, Goeran [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Industrial Ecology


    A framework for Strategic Environmental Assessment (SEA) is tested in a case study on a proposed waste incineration tax. Also included is testing of developed methods for valuation and site-dependent life cycle impact assessment. The results indicate that although a suggested waste incineration tax of 400 SEK/ton is likely to lead to environmental improvements, these are small compared to the potential improvements as shown in more visionary scenarios. In order to go in this direction a waste incineration tax based on the content of fossil carbon in the waste would be useful. The framework for SEA includes several different pathways. These have different advantages and disadvantages and provide different types of information. It is therefore suggested that they largely complement each other and that the choice of methods should be done in relation to the function of the SEA and the questions asked.

  10. 三七三醇皂苷对MCAO大鼠BDNF和TrkB表达的影响%Influence of PTS on expressions of BDNF and TrkB in MCAO rats

    Institute of Scientific and Technical Information of China (English)

    王席玲; 邹忆怀; 翟建英; 崔方圆; 朱陵群


    目的 观察三七三醇皂苷(PTS)对脑缺血大鼠模型脑源性神经营养因子(BDNF)及其酪氨酸激酶受体B(TrkB)表达的影响,揭示PTS对脑缺血受损神经元的重塑作用机制.方法 选取成年雄性SD大鼠,采用改良的EZ Longa方法建立大脑中动脉缺血(MCAO)大鼠模型,根据清醒后所得Longa评分随机分为模型组(生理盐水)、三七三醇皂苷组(三七舒通胶囊)和阳性对照组(尼莫地平),分别于给药后3、7、28 d随机取大鼠6只,通过免疫组织化学法观察BDNF和TrkB的表达,并观察大鼠脑缺血后的神经功能变化.结果 与正常组比较,术后各时间点脑组织BDNF和TrkB表达变化均有增高,并随时间的迁延呈下降的趋势.与模型组比较,三七三醇皂苷组能明显改善脑缺血的神经功能缺失症状,并能上调皮质中BDNF和TrkB蛋白的表达水平.结论 三七三醇皂苷能上调脑缺血后BDNF和TrkB蛋白的表达,可能通过上调BDNF和TrkB表达对脑缺血神经元损伤起保护作用,促进神经元的重塑,发挥其对脑缺血的治疗作用.

  11. Training Needs Assessment in the Botswana Public Service: A Case Study of Five State Sector Ministries (United States)

    Balisi, Shadreck


    Using qualitative methods, this study analysed the process of training needs assessment in the Botswana public service, with special focus on five state sector ministries. It is evident from the research findings that there is little and an unsystematic approach to the needs assessment prior to training. The research further revealed that the…

  12. A Study of the Validity and Reliability of Self-Assessment (United States)

    Mistar, Junaidi


    This study is to investigate whether self-assessment contains construct-irrelevant variances of gender and age, and whether self-assessment correlates with test scores. The data were collected from seventy-eight newly arrived international students at the English Language Center, Michigan State University, USA. Prior to class commencement, they…

  13. The Implementation of Self-Assessment in Writing Class: A Case Study at STBA LIA Jakarta (United States)

    Purwanti, Theresia Tuti


    Self-assessment has become a means of realizing the goals of learner-centered education. It is conducted to help students grow to be independent learners. With regard to this point, this case study is aimed at investigating the implementation of the self-assessment as a learning tool in writing class. Its purpose is to examine students' reactions…

  14. Rating Performance Assessments of Students with Disabilities: A Study of Reliability and Bias (United States)

    Mastergeorge, Ann M.; Martinez, Jose Felipe


    Inclusion of students with disabilities in district-wide and state assessments is mandated by federal regulations, and teachers sometimes play an important role in rating these students' work. In this study, trained teachers rated student proficiency in performance assessments in language arts and mathematics in third, fifth, and ninth grades. The…

  15. How to assess common somatic symptoms in large-scale studies : A systematic review of questionnaires

    NARCIS (Netherlands)

    Zijlema, Wilma L.; Stolk, Ronald P.; Loewe, Bernd; Rief, Winfried; White, Peter D.; Rosmalen, Judith G. M.


    Objective: Many questionnaires for assessment of common somatic symptoms or functional somatic symptoms are available and their use differs greatly among studies. The prevalence and incidence of symptoms are partially determined by the methods used to assess them. As a result, comparison across stud

  16. Synchronous Computer-Mediated Dynamic Assessment: A Case Study of L2 Spanish Past Narration (United States)

    Darhower, Mark Anthony


    In this study, dynamic assessment is employed to help understand the developmental processes of two university Spanish learners as they produce a series of past narrations in a synchronous computer mediated environment. The assessments were conducted in six weekly one-hour chat sessions about various scenes of a Spanish language film. The analysis…

  17. A Generalizability Study of Salter Environmental Type Assessment Scores by Social Climate Domain. (United States)

    Walter, Daniel W.


    The Salter Environmental Type Assessment- Experimental Form B (SETA-Form B) was designed to be a commensurate environmental assessment for the Myers-Briggs Type Indicator. This study addressed the generalizability of the SETA-Form B scores provided by 800 college students across 4 environmental domains. Although the results were mostly positive,…

  18. EMBEDding the CEFR in Academic Writing Assessment : A case study in training and standardization

    NARCIS (Netherlands)

    Haines, Kevin; Lowie, Wander; Jansma, Petra; Schmidt, Nicole


    The CEFR is increasingly being used as the framework of choice for the assessment of language proficiency at universities across Europe. However, to attain consistent assessment, familiarization and standardization are essential. In this paper we report a case study of embedding a standardization pr

  19. Assessment in Early Primary Education: An Empirical Study of Five School Contexts (United States)

    DeLuca, Christopher; Hughes, Scott


    Within the current standards-based framework of early primary education, teachers must negotiate the integration of assessment with traditional, developmental orientations to teaching and learning. The purpose of this qualitative study was to examine teachers' approaches to early primary assessment within five different school contexts: public,…

  20. Miscanthus as energy crop: Environmental assessment of a miscanthus biomass production case study in France

    DEFF Research Database (Denmark)

    Morandi, Fabiana; Perrin, A.; Østergård, Hanne


    assessment of different logistic (harvesting) strategies for miscanthus production in the Bourgogne region is presented. Emergy assessment is a particular methodology suited to quantify the resource use of a process and to estimate the percentage of renewability of products or services. The case study...

  1. Values as a Bridge between Sustainability and Institutional Assessment: A Case Study from BOKU University (United States)

    Ribeiro, Maria Miguel; Hoover, Elona; Burford, Gemma; Buchebner, Julia; Lindenthal, Thomas


    Purpose: The purpose of this paper is to illustrate that values-focused assessment can provide a useful lens for integrating sustainability and institutional performance assessment in universities. Design/methodology/approach: This study applies a values elicitation methodology for indicator development, through thematic analysis of…

  2. Assessment of Visuospatial Neglect in Stroke Patients Using Virtual Reality: A Pilot Study (United States)

    Jannink, Michiel J. A.; Aznar, Miguel; de Kort, Alexander Cornelis; van de Vis, Wim; Veltink, Peter; van der Kooij, Herman


    One of the neuropsychological deficits that can result from a stroke is the neglect phenomenon. Neglect has traditionally been assessed with paper-and-pencil tasks, which are administered within the reaching space of a person. The purpose of this explorative study is to investigate whether it is possible to assess neglect in the extrapersonal…

  3. Information Literacy and Communication Research: A Case Study on Interdisciplinary Assessment (United States)

    Natalle, Elizabeth J.; Crowe, Kathryn M.


    This report offers an interdisciplinary approach for conducting assessment on learning outcomes in undergraduate communication research skills where information literacy is embedded in the expected outcome. A Communication Studies department and the University Library piloted a two-year program to develop strategies for coordinated assessment that…

  4. Overheating Assessment of a Passive House Case Study in Spain

    DEFF Research Database (Denmark)

    Hidalgo, Juan María; Psomas, Theofanis Ch.; García-Gáfaro, Carlos


    temperatures during warm and transition seasons. Furthermore, the Intergovernmental Panel on Climate Change (IPCC) warns about increases in temperature of more than 4 ºC by the end of the century. Taking into account the different thermal comfort indices, this research analyses the overheating risk in a single...... in CIBSE TM52 in 2013 and the PH limitation about warmer temperatures. Moreover, we have analysed the influence of dwelling occupancy and the periods of verification over the results of each methodology. The studied building has a high level of thermal insulation and air-tight envelope, reducing heat...... losses until a heating demand of 14 kWh/m2 per year. It is equipped with a convective heating system and a mechanical ventilation system with heat recovery, without any cooling system apart from the bypass configuration of the heat recovery unit and the window openings. The monitoring lasted more than...

  5. Assessment

    Directory of Open Access Journals (Sweden)

    D.F. Cortés-Rojas


    Full Text Available Spray drying has been successfully employed for the encapsulation of herbal bioactive compounds resulting in stable phytopharmaceutical preparations. Bidens pilosa L. is a South American medicinal plant with proved antimalaric, hepatoprotector and antioxidant activities, generally linked to their secondary metabolites, flavonoids and polyacetylenes. In this work the physicochemical stability of an optimized spray dried composition from a B. pilosa extract was evaluated at three different stress storage conditions in open containers and in sealed sachets. High performance liquid chromatography was employed to monitor the concentration of three marker compounds over 12 months. Color variation of the stored samples was evaluated by using a color spectrophotometer. It was observed that the concentration of the monitored compounds of the plant decreases more drastically in samples stored in open containers. The two flavonoids monitored, rutin and hyperoside, showed lower degradation than the polyacetylene. The concentration of the markers did not change significantly at the lowest temperature. With regard to color, darker hues were observed at higher temperatures and storage times. This study showed that the storage conditions cause significant impact on stability of standardized spray dried B. pilosa extract.

  6. Assessment

    Directory of Open Access Journals (Sweden)

    Ahmed Ali Rashed


    Full Text Available This research was set in order to estimate aquatic plants evapotranspiration, (ET in Edfina drain, Nile Delta, Egypt, which had an in-stream treatment wetland that was taken as a case study. A simple field scale approach is presented to measure drain water evaporation and water consumption of five aquatic plants, cultivated in floating tanks. Plants ET, (ETp values were obtained by measuring the daily quantity of water required to renovate the tank’s initial volume. Crop coefficients (Kc were obtained and water loss from the drain wetland was calculated due to evaporation and plants cells ETp. Results presented values of ETp and Kc which were controlled by plant leaf area and growing stage. The major ETp was for Hyacinth followed by Cattail, Reeds, Torpedo grass, and then duckweeds. All ETp values exceeded twice the adjacent non-vegetated water evaporation. The obtained Kc values referenced to the drain water evaporation were almost twice the Kc values of FAO Penman–Monteith ET, due to the landscape effects, as hot dry air can cause extra heat input and water loss. Total losses from in-stream treatment series of pond, 4 plants reaches and open disinfection zone did not exceed 0.55% of drain discharge.

  7. Feasibility studies of safety assessment methods for programmable automation systems. Final report of the AVV project

    Energy Technology Data Exchange (ETDEWEB)

    Haapanen, P.; Maskuniitty, M.; Pulkkinen, U. [VTT Automation, Espoo (Finland); Heikkinen, J.; Korhonen, J.; Tuulari, E. [VTT Electronics, Espoo (Finland)


    Feasibility studies of two different groups of methodologies for safety assessment of programmable automation systems has been executed at the Technical Research Centre of Finland (VTT). The studies concerned the dynamic testing methods and the fault tree (FT) and failure mode and effects analysis (FMEA) methods. In order to get real experience in the application of these methods, an experimental testing of two realistic pilot systems were executed and a FT/FMEA analysis of a programmable safety function accomplished. The purpose of the studies was not to assess the object systems, but to get experience in the application of methods and assess their potentials and development needs. (46 refs., 21 figs.).

  8. Study of assessment of quality and maturity of fresh ginger

    Directory of Open Access Journals (Sweden)

    Sirinad Noypitak


    Full Text Available The research studied evaluative method of physiological properties of three stages of fresh gingers including immature stage, early mature stage and mature stage to be alternative for quality checking of maturity fresh ginger. The classification models were built based on both destructive method and non-destructive methods. The destructive variables were texture parameters, crude fiber and moisture content and the non-destructive variables were specific gravity, color (L*, a*, b*, gloss and light reflection in range 400-700 nm. The results showed that increasing of ginger harvesting date significantly affected physiological properties. The partial least squares discriminant analysis (PLS-DA was performed to create a classifying model for harvesting date of fresh ginger. The 55.56% and 100% best accuracy of classification into three stages of maturity could be achieved by the destructive model and the non-destructive model, respectively. The best applicable variables in building the non-destructive model were light reflection at 420, 450, 490, 530, 570, 590, 680 nm and the specific gravity.

  9. Assessment and seasonal variations of communicable diseases: 3 year study

    Directory of Open Access Journals (Sweden)

    D. Kalyani


    Results: Results showed that a total of 34,981 had been treated at the inpatient departments from the year 2011 to 2013. It was observed that communicable diseases constituted about 85% (30,082 of the total disease burden with viral infections being the commonest. Most of the diseases were observed to have a seasonal variation. The most common disease identified was viral fever 8713 (28.96%, secondly acute diarrheal diseases 7965(26.52% followed by enteric fever 2958 (9.83% and malaria 2443(8.12%. The least common were Rabies 80 (0.26 % and pertussis 37 (0.12%. Outbreaks of Measles and Diphtheria were also noted in this study. Conclusions: Many diseases have a seasonal variation and the burden of these diseases could be reduced if we device measures to detect the changes in their trend through the implementation of surveillance programs. The knowledge of the burden of these would also assist the health administrators in allocation of the resources. [Int J Res Med Sci 2016; 4(4.000: 1186-1192


    Directory of Open Access Journals (Sweden)



    Full Text Available INTRODUCTION : Drug – drug interactions can be defined as pharmacological or clinical respons e to the administration of drug combination s that is different from its known effects of two or more than two medicines. It frequently conjures images of a sudden catastrophic and even fatal outcome. While such an event can occur and it is important to prevent in the clinical set up. Drug interactio ns can occur by pharmacokinetic & pharmacodynamic interactions. The antipsychotics are known to have more drug interactions compared to any other class of drugs hence we aimed for the identification of drug interactions of psychiatric drugs. METHODOLOGY : T he data was collected from medication chart of inpatients in the psychiatric department and analyzed the interactions using Stockley’s drug interactions , Dipiro etc. RESULTS AND DISCUSSION : The study includes 508 samples out of which 368 case were found to have interactions. The cobalamine and panto prazole interactions were found to be 36.14% and the combination of antipsychotics , anticonvulsants with anxiolytics and anticonvulsants were 10.22 %

  11. Root Cause Assessment for a Manufacturing Industry: A Case Study

    Directory of Open Access Journals (Sweden)

    R. Kalantri


    Full Text Available Root-cause identification for quality related problems are key issues for manufacturing processes. It has been a very challenging engineering problem particularly in a multistage manufacturing, where maximum number of processes and activities are performed. However, it may also be implemented with ease in each and every individual set up and activities in any manufacturing process. Kaizen is aimed towards reduction in different types of losses i.e. Failure Loss/ Breakdown Loss, Minor stoppage, idling loss, Setup and adjustment loss etc. So as to improve quality and productivity.In this report, root-cause identification methodology has been adopted to eliminate the rejection of product manufactured by the enterprise and improving the life of product. Brainstorming and other Root Cause Assesmenttools have been used to find out the reasons of tube failure and vibration in tubular strander. Solutions of these problems have also given in this report. Kaizen activities have reduced the time consumed in daily activities of cleaning, lubricating, inspection etc. A detailed study has illustrated the effectiveness of the proposed methodology.

  12. Study on vulnerability assessment of cable-stayed bridges (United States)

    Chang, C. C.; Yan, D.


    A structure is vulnerable if any small damage will trigger disproportionately large consequences, even leads to a cascade of failure events and progressive collapse. The structural vulnerability performance depends upon the properties, locations of damaged components and the way they are connected to the rest of the structure. In this paper, progressive failure analysis method is utilized for the vulnerability study of cable-stayed bridges. The goal of it is to identify various failure scenarios initiated from the sudden damage of some bridge components. Based on the analysis results, assuming that the behaviors of damaged components can be modeled using plastic hinges, the hybrid element model is introduced to derived the modified stiffness matrix considering both of the effects of bending moments and shear forces. Furthermore, the vulnerability index in terms of the nodal stiffness degradation can be analytically quantified, which could be regarded as an index to determine the bridge failure consequences, so that the vulnerability distribution graph for the whole bridge can be sketched to evaluate the bridge performances from vulnerability viewpoints. This quantitative approach is applicable for structural evaluation under unforeseen attack and illustrated on a typical long-span cable-stayed bridge.


    Directory of Open Access Journals (Sweden)

    Daniela Nicoleta SAHLIAN


    Full Text Available During the recent financial crisis of insurance domain, there were imposed new aspects that have to be taken into account concerning the risks management and surveillance activity. The insurance societies could develop internal models in order to determine the minimum capital requirement imposed by the new regulations that are to be adopted on 1 January 2016. In this respect, the purpose of this research paper is to offer a real presentation and comparing with the main solvency regulation systems used worldwide, the accent being on their common characteristics and current tendencies. Thereby, we would like to offer a better understanding of the similarities and differences between the existent solvency regimes in order to develop the best regime of solvency for Romania within the Solvency II project. The study will show that there are clear differences between the existent Solvency I regime and the new approaches based on risk and will also point out the fact that even the key principles supporting the new solvency regimes are convergent, there are a lot of approaches for the application of these principles. In this context, the question we would try to find the answer is "how could the global solvency models be useful for the financial surveillance authority of Romania for the implementation of general model and for the development of internal solvency models according to the requirements of Solvency II" and "which would be the requirements for the implementation of this type of approach?". This thing makes the analysis of solvency models an interesting exercise.

  14. Assessing the reliability of ecotoxicological studies: An overview of current needs and approaches. (United States)

    Moermond, Caroline; Beasley, Amy; Breton, Roger; Junghans, Marion; Laskowski, Ryszard; Solomon, Keith; Zahner, Holly


    In general, reliable studies are well designed and well performed, and enough details on study design and performance are reported to assess the study. For hazard and risk assessment in various legal frameworks, many different types of ecotoxicity studies need to be evaluated for reliability. These studies vary in study design, methodology, quality, and level of detail reported (e.g., reviews, peer-reviewed research papers, or industry-sponsored studies documented under Good Laboratory Practice [GLP] guidelines). Regulators have the responsibility to make sound and verifiable decisions and should evaluate each study for reliability in accordance with scientific principles regardless of whether they were conducted in accordance with GLP and/or standardized methods. Thus, a systematic and transparent approach is needed to evaluate studies for reliability. In this paper, 8 different methods for reliability assessment were compared using a number of attributes: categorical versus numerical scoring methods, use of exclusion and critical criteria, weighting of criteria, whether methods are tested with case studies, domain of applicability, bias toward GLP studies, incorporation of standard guidelines in the evaluation method, number of criteria used, type of criteria considered, and availability of guidance material. Finally, some considerations are given on how to choose a suitable method for assessing reliability of ecotoxicity studies. Integr Environ Assess Manag. ©2016 SETAC.

  15. Assessing atmospheric temperature data sets for climate studies

    Directory of Open Access Journals (Sweden)

    Magnus Cederlöf


    Full Text Available Observed near-surface temperature trends during the period 1979–2014 show large differences between land and ocean, with positive values over land (0.25–0.27 °C/decade that are significantly larger than over the ocean (0.06–0.12 °C/decade. Temperature trends in the mid-troposphere of 0.08-0.11 °C/decade, on the other hand, are similar for both land and ocean and agree closely with the ocean surface temperature trend. The lapse rate is consequently systematically larger over land than over the ocean and also shows a positive trend in most land areas. This is puzzling as a response to external warming, such as from increasing greenhouse gases, is broadly the same throughout the troposphere. The reduced tropospheric warming trend over land suggests a weaker vertical temperature coupling indicating that some of the processes in the planetary boundary layer such as inversions have a limited influence on the temperature of the free atmosphere. Alternatively, the temperature of the free atmosphere is influenced by advection of colder tropospheric air from the oceans. It is therefore suggested to use either the more robust tropospheric temperature or ocean surface temperature in studies of climate sensitivity. We also conclude that the European Centre for Medium-Range Weather Forecasts Reanalysis Interim can be used to obtain consistent temperature trends through the depth of the atmosphere, as they are consistent both with near-surface temperature trends and atmospheric temperature trends obtained from microwave sounding sensors.

  16. Self-assessment and students' study strategies in a community of clinical practice: a qualitative study.

    NARCIS (Netherlands)

    Al-Kadri, H.M.; Al-Moamary, M.S.; Al-Takroni, H.; Roberts, C.; Vleuten, C.P.M. van der


    BACKGROUND: Self-assessment is recognized as a necessary skill for lifelong learning. It is widely reported to offer numerous advantages to the learner. The research evaluated the impact of students' and supervisors' self-assessment and feedback training on students' perceptions and practices of sel

  17. Hegemonic Masculinity in Sport Education: Case Studies of Experienced In-Service Teachers with Teaching Orientations (United States)

    Chen, YuChun; Curtner-Smith, Matthew


    Research has revealed that while pre-service teachers (PTs) with coaching orientations reinforce sexism and masculine bias, those with teaching orientations combat and reject it. The purpose of this study was to examine four sport education (SE) seasons taught by two experienced in-service teachers for the presence or absence of sexism and…

  18. Assessment of subtalar joint neutral position:a cadaveric study

    Institute of Scientific and Technical Information of China (English)

    CHEN Yan-xi; YU Guang-rong; MEI Jiong; ZHOU Jia-qian; WANG Wen


    Background Subtalar joint(STJ)neutral position is the position typically used by clinicians to obtain a cast representation of a patient's foot before fabrication of biomechanical functional orthosis. But no method for measuring STJ neutral position has been proven accurate and reproducible by different testers. This study was conducted to investigate the STJ neutral position in normal feet in cadavers. Methods Twelve fresh-frozen specimens of amputated lower legs were used. Pressure-sensitive films were inserted into the anterior and posterior articulation of STJ. The contact areas for various foot positions and under axial loads of 600 N were determined based on the gray level of the digitized film. The STJ neutral positions were determined as the ankle-foot position where the maxlmum contact area was achieved, because the neutral position of a joint was defined as the position where the concave and convex surfaces were completely congruous. Results In ankle-foot neutral position, the contact area of STJ was(2.79±0.24)cm2. In the range of motion of adduction-abduction (ADD-ABD), the maximum contact area was(3.00±0.26)cm2 when the foot was positioned 10°of ABD (F=221.361, P<0.05). In the range of motion of dorsiflexion-plantarflexion (DF-PF), the maximum contact area was (3. 61±0. 25)cm2 when the foot was positioned 20°of DF(F=121.067, P<0.05). In the range of motion of inversion-eversion (INV-EV), the maximum contact area was(3. 14+0.26)cm2 when the foot was positioned 10°of EV(F=256. 252, P<0.05). Conclusions Joints, such as STJ, therefore, are not necessarily in neutral position when the ankle. foot is placed in the traditional concept of neutral position. The results demonstrate that the most approximate STJ neutral position was in the foot position of 10°of abduction, 20°of dorsiflexion and 10°of eversion.

  19. Assessment of Social Media Utilization and Study Habit of Students of Tertiary Institutions in Katsina State (United States)

    Olutola, Adekunle Thomas; Olatoye, Olufunke Omotoke; Olatoye, Rafiu Ademola


    This study investigated assessment of social media utilization and study habits of students of tertiary institutions in Katsina State. The descriptive survey design was adopted for this study. Three hundred and eighty-one (381) students' of tertiary institutions in Katsina State were randomly selected for the study. Researchers'-designed…

  20. Understanding Authentic Assessment in a Secondary Agricultural Mechanics Laboratory: An Instrumental Case Study

    Directory of Open Access Journals (Sweden)

    J. Joey Blackburn


    Full Text Available The instrumental case study reported here adds to the literature on authentic assessment by illuminating how one secondary agricultural education instructor employed authentic assessment in the agricultural mechanics laboratory. The study was underpinned by the constructivist notion of authentic learning and assessment, or allowing students to perform what they can do. Multiple sources of data regarding assessment practices were collected from an exemplary secondary agricultural mechanics instructor who demonstrated model authentic assessment behavior by (1 setting high and fair expectations for students, (2 establishing a progressive hierarchy of skills for students to master, (3 providing continuous feedback so that students had knowledge of their progress, and (4 being committed deeply to students’ success. The four themes resonated with previous literature and provided the foundation for a pragmatic model of authentic assessment in the secondary agricultural mechanics laboratory. Future research should focus on refining the model of authentic assessment in agricultural mechanics for a larger audience, as case studies are limited in their ability to generalize. Additionally, research should be conducted to determine how authentic assessment impacts student performance on Oklahoma Agricultural Power and Technology competency examinations.

  1. Using Formative Assessments to Improve Student Learning Outcomes: A Study of the Different Types of Formative Assessments Teachers Use to Drive Instruction and Their Effects on Student Learning (United States)

    Alzina, Amy


    Understanding the difference between summative and formative assessments is still unclear for many teachers and principals as well as the effects formative assessments have on student learning outcomes. This quantitative study was conducted to explicitly explore formative assessments as a means to improve student learning outcomes, while examining…

  2. In vitro-in vivo study on the effects of plant compounds on rumen fermentation, microbial abundances and methane emissions in goats. (United States)

    Martínez-Fernández, G; Abecia, L; Martín-García, A I; Ramos-Morales, E; Hervás, G; Molina-Alcaide, E; Yáñez-Ruiz, D R


    Two in vitro and one in vivo experiments were conducted to investigate the effects of a selection of plant compounds on rumen fermentation, microbial concentration and methane emissions in goats. Treatments were: control (no additive), carvacrol (CAR), cinnamaldehyde (CIN), eugenol (EUG), propyl propane thiosulfinate (PTS), propyl propane thiosulfonate (PTSO), diallyl disulfide (DDS), a mixture (40 : 60) of PTS and PTSO (PTS+PTSO), and bromochloromethane (BCM) as positive control with proven antimethanogenic effectiveness. Four doses (40, 80, 160 and 320 µl/l) of the different compounds were incubated in vitro for 24 h in diluted rumen fluid from goats using two diets differing in starch and protein source within the concentrate (Experiment 1).The total gas production was linearly decreased (P<0.012) by all compounds, with the exception of EUG and PTS+PTSO (P≥ 0.366). Total volatile fatty-acid (VFA) concentration decreased (P≤ 0.018) only with PTS, PTSO and CAR, whereas the acetate:propionate ratio decreased (P≤ 0.002) with PTS, PTSO and BCM, and a tendency (P=0.064) was observed for DDS. On the basis of results from Experiment 1, two doses of PTS, CAR, CIN, BCM (160 and 320 µl/l), PTSO (40 and 160 µl/l) and DDS (80 and 320 µl/l) were further tested in vitro for 72 h (Experiment 2). The gas production kinetics were affected (P≤ 0.045) by all compounds, and digested NDF (DNDF) after 72 h of incubation was only linearly decreased (P≤ 0.004) by CAR and PTS. The addition of all compounds linearly decreased (P≤ 0.009) methane production, although the greatest reductions were observed for PTS (up to 96%), DDS (62%) and BCM (95%). No diet-dose interaction was observed. To further test the results obtained in vitro, two groups of 16 adult non-pregnant goats were used to study in vivo the effect of adding PTS (50, 100 and 200 mg/l rumen content per day) and BCM (50, 100 and 160 mg/l rumen content per day) during the 9 days on methane emissions (Experiment 3

  3. Development and Validation of a Pediatric Endocrine Knowledge Assessment Questionnaire: Impact of ac Pediatric Endocrine Knowledge Assessment Questionnaire Intervention Study (United States)

    Gupta, Nidhi; Zidan, Marwan; Moltz, Kathleen; Adhikari, Amita; Buggs-Saxton, Colleen; Zidan, Hanaa; Abushanab, Dania; Lteif, Aida; Edwin, Chandra


    Objective: While there is general agreement that patient education is essential for compliance, no objective tools exist to assess knowledge in children and parents of children with endocrine disorders. We aimed to design and validate a Pediatric Endocrine Knowledge Assessment Questionnaire (PEKAQ) for congenital hypothyroidism, Hashimoto’s thyroiditis, isolated growth hormone deficiency, Graves’ disease, and congenital adrenal hyperplasia. We evaluated baseline knowledge of children and parents of children with these disorders and assessed impact of educational intervention. Methods: At baseline, 77 children (12-18 years) and 162 parents of children 1-18 years participated in this prospective intervention study. Educational handouts for five targeted disorders were designed. Following one-on-one educational intervention, 55 children and 123 parents participated. Baseline and post-intervention knowledge scores were compared using McNemar’s test. Results: Adequate multi-rater Kappa measure of agreement was achieved for children’s (0.70) and parent’s (0.75) PEKAQs. Flesch Reading Ease Score for both PEKAQs (15 questions each) was 65. Post-intervention, significantly higher proportion of parents and children answered majority of questions correctly (pexercise and diet with these disorders, and long-term prognosis. Parent’s knowledge score was an independent predictor of child’s score. Conclusions: To our knowledge, this is the first validated PEKAQ that can be used widely in pediatric endocrinology clinics. We noted significant improvement in knowledge of children and parents of children with endocrine disorders. PMID:27353948

  4. Prospective Assessment of Cannabis Withdrawal in Adolescents with Cannabis Dependence: A Pilot Study (United States)

    Milin, Robert; Manion, Ian; Dare, Glenda; Walker, Selena


    A study to identify and assess the withdrawal symptoms in adolescents afflicted with cannabis dependence is conducted. Results conclude that withdrawal symptoms of cannabis were present in adolescents seeking treatment for this substance abuse.

  5. Webinar Presentation: Epidemiologic Studies of the Effects of Toxic Exposures on Brain and Behavior: Neuropsychological Assessment (United States)

    This presentation, Epidemiologic Studies of the Effects of Toxic Exposures on Brain and Behavior: Neuropsychological Assessment, was given at the NIEHS/EPA Children's Centers 2015 Webinar Series: Interdisciplinary Approaches to Neurodevelopment.

  6. A risk assessment study on work-related musculoskeletal disorders among dentists in Bhopal, India

    Directory of Open Access Journals (Sweden)

    Chetna Batham


    Conclusion: This risk assessment study found that there is a high prevalence of MSDs and WMSDs among dentists. Ergonomic awareness and health promotion need to be integrated with the professional practice for dentists.

  7. Dta points used in assessment of coal in the southern Piceance basin study area (psptg) (United States)

    U.S. Geological Survey, Department of the Interior — This is a shapefile and point coverage of 627 data points used in the assessment of coal in the southern Piceance Basin study area. Information in this file includes...


    Trihalomethanes are common contaminants of chlorinated drinking water. Studies of their health effects have been hampered by exposure misclassification, due in part to limitations inherent in using utility sampling records. We used two exposure assessment methods, one based on ut...

  9. Revision Vodcast Influence on Assessment Scores and Study Processes in Secondary Physics (United States)

    Marencik, Joseph J.

    A quasi-experimental switching replications design with matched participants was employed to determine the influence of revision vodcasts, or video podcasts, on students' assessment scores and study processes in secondary physics. This study satisfied a need for quantitative results in the area of vodcast influence on students' learning processes. Thirty-eight physics students in an urban Ohio public high school participated in the study. The students in one Physics class were paired with students in another Physics class through the matching characteristics of current student cumulative test score mean and baseline study process as measured by the Study Process Questionnaire (SPQ). Students in both classes were given identical pedagogic treatment and access to traditional revision tools except for the supplemental revision vodcasts given to the experimental group. After students in the experimental group viewed the revision vodcast for a particular topic, the assessment scores of the students in the experimental group were compared to the assessment scores of the control group through the direct-difference, D, test to determine any difference between the assessment score means of each group. The SPQ was given at the beginning of the experiment and after each physics assessment. The direct-difference method was again used to determine any difference between the SPQ deep approach scores of each group. The SPQ was also used to determine any correlative effects between study process and revision vodcast use on students' assessment scores through descriptive statistics and an analysis of variance (ANOVA) test. Analysis indicated that revision vodcast use significantly increased students' assessment scores (p.05). There were no significant correlative effects of revision vodcast use and study processes on students' assessment scores (p>.05). This study offers educators the empirical support to devote the necessary effort, time, and resources into developing successful

  10. Profiling postgraduate workplace-based assessment implementation in Ireland: a retrospective cohort study


    Barrett, Aileen; Galvin, Rose; Steinert, Yvonne; Scherpbier, Albert; O’Shaughnessy, Ann; Walsh, Gillian; Horgan, Mary


    In 2010, workplace-based assessment (WBA) was formally integrated as a method of formative trainee assessment into 29 basic and higher specialist medical training (BST/HST) programmes in six postgraduate training bodies in Ireland. The aim of this study is to explore how WBA is being implemented and to examine if WBA is being used formatively as originally intended. A retrospective cohort study was conducted and approved by the institution’s Research Ethics Committee. A profile of WBA require...

  11. Assessing Motor Skill Competency in Elementary School Students: A Three-Year Study. (United States)

    Chen, Weiyun; Mason, Steve; Hypnar, Andrew; Bennett, Austin


    This study was to examine how well fourth- and fifth-grade students demonstrated motor skill competency assessed with selected PE Metrics assessment rubrics (2009). Fourth- and fifth-grade students (n = 1,346-1,926) were assessed on their performance of three manipulative skills using the PE Metrics Assessment Rubrics during the pre-intervention year, the post-intervention year 1, and the post-intervention year 3. Descriptive statistics, independent t-test, ANOVA, and follow-up comparisons were conducted for data analysis. The results indicated that the post-intervention year 2 cohort performed significantly more competent than the pre-intervention cohort and the post-intervention year 1 cohort on the three manipulative skill assessments. The post-intervention year 1 cohort significantly outperformed the pre-intervention cohort on the soccer dribbling, passing, and receiving and the striking skill assessments, but not on the throwing skill assessment. Although the boys in the three cohorts performed significantly better than the girls on all three skills, the girls showed substantial improvement on the overhand throwing and the soccer skills from baseline to the post-intervention year 1 and the post-intervention year 2. However, the girls, in particular, need to improve striking skill. The CTACH PE was conducive to improving fourth- and fifth-grade students' motor skill competency in the three manipulative skills. This study suggest that PE Metrics assessment rubrics are feasible tools for PE teachers to assess levels of students' demonstration of motor skill competency during a regular PE lesson. Key pointsCATCH PE is an empirically-evidenced quality PE curricular that is conducive to improving students' manipulative skill competency.Boys significantly outperformed than girls in all three manipulative skills.Girls need to improve motor skill competency in striking skill. PE Metrics are feasible assessment rubrics that can be easily used by trained physical

  12. A study on assessment methodology of surveillance test interval and Allowed Outage Time

    Energy Technology Data Exchange (ETDEWEB)

    Che, Moo Seong; Cheong, Chang Hyeon; Ryu, Yeong Woo; Cho, Jae Seon; Heo, Chang Wook; Kim, Do Hyeong; Kim, Joo Yeol; Kim, Yun Ik; Yang, Hei Chang [Seoul National Univ., Seoul (Korea, Republic of)


    Objectives of this study is the development of methodology by which assesses the optimization of Surveillance Test Interval(STI) and Allowed Outage Time(AOT) using PSA method that can supplement the current deterministic methods and the improvement of Korean nuclear power plants safety. In the first year of this study, the survey about the assessment methodologies, modeling and results performed by domestic and international researches are performed as the basic step before developing the assessment methodology of this study. The assessment methodology that supplement the revealed problems in many other studies is presented and the application of new methodology into the example system assures the feasibility of this method. In the second year of this study, the sensitivity analyses about the failure factors of the components are performed in the bases of the assessment methodologies of the first study, the interaction modeling of the STI and AOT is quantified. And the reliability assessment methodology about the diesel generator is reviewed and applied to the PSA code.

  13. An Assessment of the Study Habits and Skills of Students in Postsecondary Science Courses. (United States)

    Kuhn, David J.


    Discusses a study conducted at Wilson County Technical College, North Carolina, to assess the study habits and skills of 74 students enrolled in basic science courses in 1987. Student responses to the Study Behavior Inventory-Form D suggest that students had difficulty with time management and keeping up-to-date with assignments. (DMM)

  14. Alflutop in osteoarthritis therapy

    Directory of Open Access Journals (Sweden)

    G. V. Lukina


    Full Text Available Objective. To study efficacy and safety of different schemes of alflutop (AT administration in pts with osteoarthritis (OA. Material and methods 45 pts (40 womene and 5 men with knee or hip OA or nodular form of the disease were included. Mean age was 60,3± 10,0 years, mean disease duration - 8,0±6,0 years, mean duration of the last exacerbation - 5,6±5,4 months. Pts with 2 (27 pts and 3(15 pts X-ray OA stage and 2 functional class (30 pts prevailed. Pts were devided into 3 comparable groups, 15 pts in each. Pts of the group 1 received AT I ml/day intramuscularly (im during 3 weeks, group 2 pts received intra-articular (ia injections of AT 2 ml twice a week for 3 weeks and then im for 20 days. In group 3 ia (6 and im (20 injections were performed^simultaneously. During 12 months of follow up every pt received 2 appropriate courses. Results. 41 pts completed the study. AT significantly decreased joint pain at rest and at movement measured visual analog scale and WOMAC index in all groups. It also improved functional activity of pts (according to WOMAC index. Improvement according to doctor assessment was achieved after the second course in 78% of pts in group I, in 92% in group 2 and in 86% in group 3. Sonography of knee joints showed significant decrease of synovial membrane thickness (as a sign of synovitis as well as increase parts of intra-articular hyaline cartilage thickness in group 2 and 3 pts. There was no radiological progression year of follow up. Tolerability was good. The drug was stopped due to adverse events in only 3 pts (dermatitis at the site of injection-1, increase of joint pain after intra-articular injections- 2 . In 3 other pts side effects were mild, and treatmend was continued. Conclusion. Combined Im and AT administration provides anti-inflammatory, analgesic and possible chondroprotective effect in OA pts.


    Directory of Open Access Journals (Sweden)

    Junaidi Mistar


    Full Text Available his study is to investigate whether self-assessment contains construct- irrelevant variances of gender and age, and whether self-assessment correlates with test scores. The data were collected from seventy-eight newly arrived international students at the English Lan­guage Center, Michigan State University, USA. Prior to class com­mencement, they were asked to self-assess their listening, speaking, and interactive skill. Then, a test of listening was administered; finally, they were assigned to perform task-based conversational activities.The statistical findings imply that, firstly, gender and age do not provide construct irrelevant variances to the validity of self-assessment and, se­condly, self-assessment produces reliable scores.

  16. Constructivist assessment proposal a case study in a technical and industrial school environment

    Directory of Open Access Journals (Sweden)

    Carol Yohana Suescún Pinilla


    Full Text Available This article is part of the ongoing research “Constructivist AssessmentProposal” held at Institución Educativa Técnica Integral in Sogamoso. It isaimed at identifying why the assessment traditional approach is still beingapplied. Besides, it pretends to redefine new assessment practices in order toenhance students’ participation, speech and creativity. Likewise, it tends tomake teachers be aware of alternative assessment ways more relevant withthe education needs and demands. It is based on the case study researchapproach and developed in three stages: problematic description andcontextualization, analysis and comprehension of the assessment used bythe teacher in a technical and industrial setting and improvement alternativeproposals based on the problematic situation.

  17. Psychoanalytic psychotherapy assessment in a child and adolescent mental health setting: an exploratory study. (United States)

    Petit, Cécile; Midgley, Nick


    Undertaking assessment is a significant component of a Child Psychotherapist's work within Child and Adolescent Mental Health Services (CAMHS), yet as an activity it has been relatively neglected in the research literature. This study made use of a small-scale, qualitative design to explore the nature and function of psychoanalytic assessment work within a single CAMHS team. After an initial audit of child psychotherapy assessment work, indepth interviews with 5 Child and Adolescent Psychotherapists, exploring the nature of assessment work, were analysed using Interpretative Phenomenological Analysis (IPA). Results suggested that assessment is a major part of the Child Psychotherapist's work, although there are different types of assessment done in different contexts. Among the participants there was a certain shared understanding of the psychoanalytic approach to assessment, although with significant differences in regard to process, technique (e.g. use of interpretation, the role of countertransference) and the reporting of assessments. The analysis also suggested tensions between the role of the assessor as an 'expert' and as a 'therapist'.

  18. Written reflection and drawing as assessment: A case study of a Navajo elementary science classroom (United States)

    Becker, Madeline

    The purpose of the study was to assess if science learning could be determined by using written reflection and drawings in a science classroom of 5 th-grade Navajo students. The significance of this study was the understanding of the culture, assessments and learning of Navajo students. I studied a classroom on the Navajo reservation wherein 26 members of the class took part in science instruction complemented by using writing and drawing which were used as their assessments. The perceptions of the 8 students who were interviewed represent the case. In the study I profiled the 8 participants. Their culture, language, and views on assessment and learning were documented by their words. Their responses described their learning experiences. Assessments were seen as frustrating and limiting expression of what was known and damaging when not contributed to learning. Students explained that drawing enabled them to remember along with provoking vocabulary development. Student cultural knowledge was documented as valuable background experience contributing to learning within the classroom. Students viewed science as needing to be useful in their culture. Finally, they were also very candid that their teachers must first get to know them for meaningful learning to begin. Learning for students was reinforced through writing and drawing the lesson's activities. Further concept development was assisted utilizing metacognition and creative problem solving techniques of elaboration and fluency applied to the writing and drawings. Based on the findings of this study, recommendations were made for use of holistic means of assessing Navajo children in science where preferred learning styles along with cultural background need to be included in assessment protocols. Using new and better assessment techniques can directly impact how students document their learning as well as reveal how they acquire new knowledge.

  19. Phd study of reliability and validity: One step closer to a standardized music therapy assessment model

    DEFF Research Database (Denmark)

    Jacobsen, Stine Lindahl

    The paper will present a phd study concerning reliability and validity of music therapy assessment model “Assessment of Parenting Competences” (APC) in the area of families with emotionally neglected children. This study had a multiple strategy design with a philosophical base of critical realism...... and pragmatism. The fixed design for this study was a between and within groups design in testing the APCs reliability and validity. The two different groups were parents with neglected children and parents with non-neglected children. The flexible design had a multiple case study strategy specifically...... of the theoretical understanding of the clientgroup. Furthermore, a short describtion of the specific assessment protocol and analysis procedures of APC will be a part of the presentation. The phd study sought to explore how to develop measures of parenting competences in looking at autonomy relationship...

  20. A study on assessment methodology of surveillance test interval and allowed outage time

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Chang Hyun; You, Young Woo; Cho, Jae Seon; Huh, Chang Wook; Kim, Do Hyoung; Kim, Ju Youl; Kim, Yoon Ik; Yang, Hui Chang; Park, Kang Min [Seoul National Univ., Seoul (Korea, Republic of)


    The objectives of this study is the development of methodology by which assesses the optimization of Surveillance Test Internal(STI) and Allowed Outage Time(AOT) using PSA method that can supplement the current deterministic methods and the improvement of Korean nuclear power plant safety. In this study, the survey about the assessment methodologies, modelings and results performed by domestic and international researches are performed as the basic step before developing the assessment methodology of this study. The assessment methodology that supplement the revealed problems in many other studies is presented and the application of new methodology into the example system assures the feasibility of this method. The sensitivity analyses about the failure factors of the components are performed in the bases of the and AOT is quantified. And the reliability assessment methodology about the diesel generator is reviewed and applied to the PSA code. The qualitative assessment for the STI/AOR of RPS/ESFAS assured safety the most important system in the nuclear power plant are performed.

  1. Study of personality’s temperament and self-assessment of higher educational establishments’ students

    Directory of Open Access Journals (Sweden)

    Liashenko V.N.


    Full Text Available Purpose: analysis of temperament and self-assessment characteristics in higher educational establishment students. Material: in the research 1st and 2nd year students (n=30 participated. Questioning was used, with the help of which personality’s self assessment and temperament characteristics were estimated. Results: the study of students’ temperament structure showed low demand in mastering of objective world and strive for mental and physical labor. High indicator of social activity and interpersonal skills was registered. The following indicators of self-assessment were received: 15% of students had too low self-assessment, 50% of students have adequate self-assessment and 10% have excessively high self-assessment. Conclusions: quickness of psychic processes (tem and rhythm, impressiveness and emotional sensitivity are important features of temperament. Students demonstrated feeling of anxiety and worry in respect to their studying at university. Besides the have sensitivity to failures to non coincidence of the desired and the results. студентов. With it students have adequate self assessment.

  2. Interrogating the Generalizability of Portfolio Assessments of Beginning Teachers: A Qualitative Study

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    Pamela A. Moss


    Full Text Available This qualitative study is intended to illuminate factors that affect the generalizability of portfolio assessments of beginning teachers. By generalizability, we refer here to the extent to which the portfolio assessment supports generalizations from the particular evidence reflected in the portfolio to the conception of competent teaching reflected in the standards on which the assessment is based. Or, more practically, “The key question is, ‘How likely is it that this finding would be reversed or substantially altered if a second, independent assessment of the same kind were made?’” (Cronbach, Linn, Brennan, and Haertel, 1997, p. 1. In addressing this question, we draw on two kinds of evidence that are rarely available: comparisons of two different portfolios completed by the same teacher in the same year and comparisons between a portfolio and a multi-day case study (observation and interview completed shortly after portfolio submission intended to parallel the evidence called for in the portfolio assessment. Our formative goal is to illuminate issues that assessment developers and users can take into account in designing assessment systems and appropriately limiting score interpretations.

  3. Two-dimensional strain analysis of the global and regional myocardial function for the differentiation of pathologic and physiologic left ventricular hypertrophy: a study in athletes and in patients with hypertrophic cardiomyopathy. (United States)

    Butz, T; van Buuren, F; Mellwig, K P; Langer, C; Plehn, G; Meissner, A; Trappe, H J; Horstkotte, D; Faber, L


    Two-dimensional strain (2DS) is a novel method to measure strain from standard two-dimensional echocardiographic images by speckle tracking, which is less angle dependent and more reproducible than conventional Doppler-derived strain. The objective of our study was to characterize global and regional function abnormalities using 2DS and strain rate analysis in patients (pts) with pathological left ventricular hypertrophy (LVH) caused by non-obstructive hypertrophic cardiomyopathy (HCM), in top level athletes, and in healthy controls. The hypothetical question was, if 2DS might be useful as additional tool in differentiating between pathologic and physiologic hypertrophy in top-level athletes. We consecutively studied 53 subjects, 15 pts with hypertrophic cardiomyopathy (HCM), 20 competitive top-level athletes, and a control group of 18 sedentary normal subjects by standard echocardiography according to ASE guidelines. Global longitudinal strain (GLS) and regional peak systolic strain (PSS) was assessed by 2DS in the apical four-chamber-view using a dedicated software. All components of strain were significantly reduced in pts with HCM (GLS: -8.1 ± 3.8%; P < 0.001) when compared with athletes (-15.2 ± 3.6%) and control subjects (-16.0 ± 2.8%). In general, there was no significant difference between the strain values of the athletes and the control group, but in some of the segments, the strain values of the control group were significantly higher than those in the athletes. A cut-off value of GLS less than -10% for the diagnosis of pathologic hypertrophy (HCM) resulted in a sensitivity of 80.0% and a specificity of 95.0%. The combination of TDI (averaged S', E') and 2DS (GLS) cut-off values for the detection of pathologic LVH in HCM demonstrated a sensitivity of 100%, and a specificity of 95%. Two-dimensional strain is a new simple and rapid method to measure GLS and PSS as components of systolic strain. This technique could offer a unique approach to quantify

  4. Revisiting the Integrated Pressurized Thermal Shock Studies of an Aging Pressurized Water Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Bryson, J.W.; Dickson, T.L.; Malik, S.N.M.; Simonen, F.A.


    The Integrated Pressurized Thermal Shock (IPTS) studies were a series of studies performed in the early-mid 1980s as part of an NRC-organized comprehensive research project to confirm the technical bases for the pressurized thermal shock (PTS) rule, and to aid in the development of guidance for licensee plant-specific analyses. The research project consisted of PTS pilot analyses for three PWRs: Oconee Unit 1, designed by Babcock and Wilcox; Calvert Cliffs Unit 1, designed by Combustion Engineering; and H.B. Robinson Unit 2, designed by Westinghouse. The primary objectives of the IPTS studies were (1) to provide for each of the three plants an estimate of the probability of a crack propagating through the wall of a reactor pressure vessel (RPV) due to PTS; (2) to determine the dominant overcooling sequences, plant features, and operator actions and the uncertainty in the plant risk due to PTS; and (3) to evaluate the effectiveness of potential corrective actions. The NRC is currently evaluating the possibility of revising current PTS regulatory guidance. Technical bases must be developed to support any revisions. In the years since the results of IPTS studies were published, the fracture mechanics model, the embrittlement database, embrittlement correlation, inputs for flaw distributions, and the probabilistic fracture mechanics (PFM) computer code have been refined. An ongoing effort is underway to determine the impact of these fracture-technology refinements on the conditional probabilities of vessel failure calculated in the IPTS Studies. This paper discusses the results of these analyses performed for one of these plants.

  5. A Study on improvement of environmental assessment system in social, economic, and environmental sectors

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Young Sook; Koo, Doh Wan; Keum, Kee Yong [Korea Environment Institute, Seoul (Korea)


    The environmental assessment system is assessed as a mechanism that can achieve the goal for environmental policy in 21st century. As it can evaluate social and economic feasibility of large-scale development program, this system can achieve a sustainable society by mitigating social conflicts arising from environmental problems. For making the environmental assessment system substantial, this study was implemented by the need of improvement of the system, by analyzing problems of social, economic, and environmental evaluation, which is implemented under the present system. 44 refs., 1 fig., 25 tabs.

  6. Assessing personality change in psychotherapy with the SWAP-200: a case study. (United States)

    Lingiardi, Vittorio; Shedler, Jonathan; Gazzillo, Francesco


    Many studies document the efficacy of psychotherapy for acute syndromes such as depression, but less is known about personality change in patients treated for personality pathology. The Shedler-Westen Assessment Procedure (SWAP-200; Westen & Shedler, 1999a, 1999b) is an assessment tool that measures a broad spectrum of personality constructs and is designed to bridge the gap between the clinical and empirical traditions in personality assessment. In this article, we demonstrate the use of the SWAP-200 as a measure of change in a case study of a patient diagnosed with borderline personality disorder. We collected assessment data at the start of treatment and after 2 years of psychotherapy. The findings illustrate the personality processes targeted in intensive psychotherapy for borderline personality.

  7. 基于聚龙一号装置的超高速飞片发射实验研究进展%Recent advances in hyp er-velo city flyer launch exp eriments on PTS

    Institute of Scientific and Technical Information of China (English)

    王贵林; 陈宏; 丰树平; 计策; 夏明鹤; 卫兵; 田青; 李勇; 丁瑜; 郭帆; 郭帅; 沈兆武; 张朝辉; 刘仓理; 李军; 章征伟; 贾月松; 赵小明


    磁驱动加载技术通过脉冲功率源将超大脉冲电流加载到实验负载区,从而形成随时间平滑上升的磁压力,实现对样品的准等熵压缩和超高速飞片发射.本文基于聚龙一号装置的输出特性参数,依次从负载结构、电极尺寸、电流波形和诊断系统等方面,分别设计完成了两种负载构型的超高速飞片发射实验.其中应用单侧带状负载发射尺寸Φ10 mm ×0.725 mm的LY12铝飞片速度达到11.5 km/s,磁驱动加载压力近0.9 Mbar.比较模拟计算与实验结果,飞片发射过程和最终速度基本一致.而进一步的模拟计算表明,优化的负载结构尺寸和电流波形调节方案下,将有望发射尺寸Φ8.5 mm ×1 mm的铝飞片速度超过15 km/s.从模拟设计到实验开展,已初步掌握了基于多支路脉冲功率发生器的超高速飞片发射实验技术.%Magnetically driven loading technology is to load the large pulse current to the test area through the pulsed power, which forms a smooth magnetic pressure rising over time to achieve a quasi-isentropic compression of sample and hyper-velocity flyer launch. Based on the output characteristics and parameters of PTS accelerator, two types of hyper-velocity flyer launch experiments with different load configurations, such as the load, flyer plates size, current waveform and diagnostic systems, etc, are designed and tested. LY12 aluminum flyer plates with dimensions of Φ10 mm × 0.725 mm was launched by single-sided stripline load configuration to 11.5 km/s while the magnetic drive load pressure is near 0.9 × 105 MPa. Simulation and experimental results agrees well with those of in the flyer launch process and the ultimate velocity. Further simulation shows that the launch velocity of aluminum flyer plates with dimensions of Φ8.5 mm × 1 mm is expected to exceed 15 km/s under the program of optimizing the structural parameters and regulation. The design and experiment technology of hyper

  8. A socio-constructivist perspective on self-assessment: a study case

    Directory of Open Access Journals (Sweden)

    Paola Nicolini


    Full Text Available In this paper, our goal is to deal with self-assessment according to a socio-constructivist approach. We offer some data about different versions of the same Workshop, considered as a case study. Between the possibility to adopt a completely goal-driven or a fully goal-free self assessment, we suggest the adoption of a blended modality, in order to involve students in the learning process and make them aware about the learning outcomes.

  9. Orbital Atherectomy Plaque Modification Assessment of the Femoropopliteal Artery Via Intravascular Ultrasound (TRUTH Study)


    Babaev, Anvar; Zavlunova, Susanna; Attubato, Michael J.; Martinsen, Brad J.; Mintz,Gary S.; Maehara, Akiko


    Objective: The Tissue Removal Assessment with Ultrasound of the SFA and Popliteal (TRUTH) study assessed the performance of the orbital atherectomy system (OAS) to treat femoropopliteal arteries, including determining its effect on plaque removal. Methods: Patients with symptomatic femoropopliteal peripheral arterial disease were treated with the OAS followed by adjunctive balloon angioplasty (BA). Intravascular ultrasound (IVUS) images were collected pre- and post-OAS and post-OAS BA. Patien...



    M. Shamim Ahmad; Vijaya Subramaniam; Halimah Mohammad; Anis Mokhtar; Ismail, B. S.


    Life Cycle Assessment (LCA) is an important tool for identifying potential environmental impacts associated with the production of palm based plywood. This study is to make available the life cycle inventory for gate-to-gate data so that the environmental impact posed by oil palm based plywood production can be assessed. Conducting an LCA on the palm based plywood that are derived from the wastes of the oil palm industry is a first step towards performing green environmental product. Therefor...

  11. Study on wave energy resource assessing method based on altimeter data—A case study in Northwest Pacific

    Institute of Scientific and Technical Information of China (English)

    WAN Yong; ZHANG Jie; MENG Junmin; WANG Jing; DAI Yongshou


    Wave energy resource is a very important ocean renewable energy. A reliable assessment of wave energy resources must be performed before they can be exploited. Compared with wave model, altimeter can provide more accuratein situ observations for ocean wave which can be as a novel method for wave energy assessment. The advantage of altimeter data is to provide accurate significant wave height observations for wave. In order to develop characteristic and advantage of altimeter data and apply altimeter data to wave energy assessment, in this study, we established an assessing method for wave energy in local sea area which is dedicated to altimeter data. This method includes three parts including data selection and processing, establishment of evaluation indexes system and criterion of regional division. Then a case study of Northwest Pacific was performed to discuss specific application for this method. The results show that assessing method in this paper can assess reserves and temporal and spatial distribution effectively and provide scientific references for the siting of wave power plants and the design of wave energy convertors.

  12. E-assessment of prior learning: a pilot study of interactive assessment of staff with no formal education who are working in Swedish elderly care (United States)


    Background The current paper presents a pilot study of interactive assessment using information and communication technology (ICT) to evaluate the knowledge, skills and abilities of staff with no formal education who are working in Swedish elderly care. Methods Theoretical and practical assessment methods were developed and used with simulated patients and computer-based tests to identify strengths and areas for personal development among staff with no formal education. Results Of the 157 staff with no formal education, 87 began the practical and/or theoretical assessments, and 63 completed both assessments. Several of the staff passed the practical assessments, except the morning hygiene assessment, where several failed. Other areas for staff development, i.e. where several failed (>50%), were the theoretical assessment of the learning objectives: Health, Oral care, Ergonomics, hygiene, esthetic, environmental, Rehabilitation, Assistive technology, Basic healthcare and Laws and organization. None of the staff passed all assessments. Number of years working in elderly care and staff age were not statistically significantly related to the total score of grades on the various learning objectives. Conclusion The interactive assessments were useful in assessing staff members’ practical and theoretical knowledge, skills, and abilities and in identifying areas in need of development. It is important that personnel who lack formal qualifications be clearly identified and given a chance to develop their competence through training, both theoretical and practical. The interactive e-assessment approach analyzed in the present pilot study could serve as a starting point. PMID:24742168

  13. Assessing Motor Skill Competency in Elementary School Students: A Three-Year Study

    Directory of Open Access Journals (Sweden)

    Weiyun Chen, Steve Mason, Andrew Hypnar, Austin Bennett


    Full Text Available This study was to examine how well fourth- and fifth-grade students demonstrated motor skill competency assessed with selected PE Metrics assessment rubrics (2009. Fourth- and fifth-grade students (n = 1,346-1,926 were assessed on their performance of three manipulative skills using the PE Metrics Assessment Rubrics during the pre-intervention year, the post-intervention year 1, and the post-intervention year 3. Descriptive statistics, independent t-test, ANOVA, and follow-up comparisons were conducted for data analysis. The results indicated that the post-intervention year 2 cohort performed significantly more competent than the pre-intervention cohort and the post-intervention year 1 cohort on the three manipulative skill assessments. The post-intervention year 1 cohort significantly outperformed the pre-intervention cohort on the soccer dribbling, passing, and receiving and the striking skill assessments, but not on the throwing skill assessment. Although the boys in the three cohorts performed significantly better than the girls on all three skills, the girls showed substantial improvement on the overhand throwing and the soccer skills from baseline to the post-intervention year 1 and the post-intervention year 2. However, the girls, in particular, need to improve striking skill. The CTACH PE was conducive to improving fourth- and fifth-grade students’ motor skill competency in the three manipulative skills. This study suggest that PE Metrics assessment rubrics are feasible tools for PE teachers to assess levels of students’ demonstration of motor skill competency during a regular PE lesson.

  14. Assessing Honor Code Effectiveness: Results of a Multipronged Approach from a Five Year Study (United States)

    Sledge, Sally; Pringle, Pam


    This paper describes an ongoing study at a small public university to assess student, faculty and alumni perceptions of academic integrity and business ethics. The phases of the research are detailed for application or replication by other institutions of higher education. The study involves anonymous surveys and academic integrity-based…

  15. 78 FR 12335 - Submission for OMB review; Comment Request: Methodological Studies for the Population Assessment... (United States)


    ... HUMAN SERVICES National Institutes of Health Submission for OMB review; Comment Request: Methodological Studies for the Population Assessment of Tobacco and Health (PATH) Study SUMMARY: Under the provisions of... request to review and approve the information collection listed below. This proposed...

  16. Systematic review of foodborne burden of disease studies: Quality assessment of data and methodology

    NARCIS (Netherlands)

    J.A. Haagsma (Juanita); S. Polinder (Suzanne); C. Stein (Claudia); A.H. Havelaar (Arie)


    textabstractBurden of disease (BoD) studies aim to identify the public health impact of different health problems and risk factors. To assess BoD, detailed knowledge is needed on epidemiology, disability and mortality in the population under study. This is particularly challenging for foodborne dise

  17. Preferred question types for computer-based assessment of clinical reasoning: a literature study. (United States)

    van Bruggen, Lisette; Manrique-van Woudenbergh, Margreet; Spierenburg, Emely; Vos, Jacqueline


    Clinical reasoning is a core competence of doctors. Therefore, the assessment of clinical reasoning of undergraduate students is an important part of medical education. Three medical universities in the Netherlands wish to develop a shared question database in order to assess clinical reasoning of undergraduate students in Computer-Based Assessments (CBA). To determine suitable question types for this purpose a literature study was carried out. Search of ERIC and PubMed and subsequent cross referencing yielded 30 articles which met the inclusion criteria of a focus on question types suitable to assess clinical reasoning of medical students and providing recommendations for their use. Script Concordance Tests, Extended Matching Questions, Comprehensive Integrative Puzzles, Modified Essay Questions/Short Answer Questions, Long Menu Questions, Multiple Choice Questions, Multiple True/False Questions and Virtual Patients meet the above-mentioned criteria, but for different reasons not all types can be used easily in CBA. A combination of Comprehensive Integrative Puzzles and Extended Matching Questions seems to assess most aspects of clinical reasoning and these question types can be adapted for use in CBA. Regardless of the question type chosen, patient vignettes should be used as a standard stimulus format to assess clinical reasoning. Further research is necessary to ensure that the combination of these question types produces valid assessments and reliable test results.

  18. Assessing progression of clinical reasoning through virtual patients: An exploratory study. (United States)

    Forsberg, Elenita; Ziegert, Kristina; Hult, Håkan; Fors, Uno


    To avoid test-driven learning, there have been discussions regarding the use of more formative assessments in health care education to promote students' deep learning. Feedback is important in formative assessment, but many students ignore it; therefore, interventions should be introduced which stimulate them to reflect on the new knowledge. The aim for this study was to explore if Virtual Patient (VP)-based formative assessments, in connection with self-evaluations, had an impact on postgraduate pediatric nursing students' development of clinical reasoning abilities. Students' self-evaluations served as the basis for measuring progress. Data was analysed using deductive content analysis. The findings showed a clear progression of the clinical reasoning ability of the students. After the first assessment, the students described feelings of uncertainty and that their knowledge gaps were exposed. At the mid-course assessment the awareness of improved clinical reasoning was obvious and the students were more certain of knowing how to solve the VP cases. In the final assessment, self-efficacy was expressed. VP-based assessments, in connection with self-evaluations, early in the education resulted in a gain of students' own identification of the concept of clinical reasoning, awareness of what to focus on during clinical practice and visualised expected clinical competence.

  19. Worth it? Findings from a study of how academics assess students’ Web 2.0 activities

    Directory of Open Access Journals (Sweden)

    Kathleen Gray


    Full Text Available Educational commentators have offered many pedagogical rationales for using Web 2.0 to support learning in higher education, and academics are being encouraged to find ways for their students to use social web technologies. Questions arise as to the value of these activities compared to more conventional assignments, and whether implementing such changes to student assessment is worth the effort. We conducted a survey of academics’ assessment of students’ Web 2.0 activities in Australian universities and found that this form of assessment is being conducted by a small number of academics, in a range of fields of study, but mainly in Humanities and Social Sciences, with varying kinds of intended and actual learning outcomes. Blogging and wiki-writing predominate, low and medium-stakes assessment are most common, and different methods of marking and feedback are in use. Qualitative feedback from the survey and follow-up interviews gave further insights into benefits and challenges of Web 2.0 assessment in relation to pedagogy, policy and practice. It appears that academics’ conservative approaches to conducting assessment and their novice approaches to utilising social web technologies are factors which seriously limit realising the potential of Web 2.0 for medium or high-stakes assessment.

  20. Assessment of scapular positioning and function as future effect measure of shoulder interventions – an inter-examiner reliability study of the clinical assessment methods

    DEFF Research Database (Denmark)

    Larsen, Camilla Marie; Eshøj, Henrik; Ingwersen, Kim Gordon


    only been tested for intra-examiner reliability. The objective was to investigate the inter-examiner reliability of an extended battery of clinical tests for assessing scapular positioning and function. Methods A standardized three-phase protocol for clinical reliability studies was conducted......Assessment of scapular positioning and function as future effect measure of shoulder interventions – an inter-examiner reliability study of the clinical assessment methods Eshøj H1, Ingwersen KG1, Larsen CM1, 2, Søgaard K1, Juul-Kristensen B1, 3 1 University of Southern Denmark, Institute of Sports...... in three tests due to constant measurements from one of the testers. Conclusion An extended assessment battery to investigate the inter-examiner reliability for assessing the scapular positioning and function were compiled. Systematic bias between testers appeared in some, but not all assessment methods...

  1. A retrospective cohort study among iron-steel workers in Anshan, China: exposure assessment. (United States)

    Hoshuyama, Tsutomu; Pan, Guowei; Tanaka, Chieko; Feng, Yiping; Yu, Lianzheng; Liu, Tiefu; Liu, Liming; Hanaoka, Tomoyuki; Takahashi, Ken


    Although adequate assessment of exposure is needed in epidemiological studies among foundry workers, previous studies are often lacking in this aspect. We conducted a retrospective cohort study of a Chinese iron and steel company with a 14-yr follow up during 1980-1993. Exposure assessment was performed for a single job, i.e., the current job for the active worker and the longest job for the retired or deceased worker as of the end of the follow-up, which was allocated as the surrogate of lifetime job and was applied to a job-exposure matrix. Of the 147,062 cohort members, 52,394 males (43%) and 5,291 females (21%) were exposed to any of 15 hazardous factors such as dust, silica, PAHs (polycyclic aromatic hydrocarbons), CO (carbon monoxide) and heat. In 2,104 randomly selected samples, the exposure assessment of exposed workers based on a single job was found to be 12-14% lower than the real situation. This study suggests that the exposure assessment is valuable in evaluating the health effects among the foundry workers, despite some limitations such as underestimation of exposure assessment and the lack of data regarding smoking and drinking habits.

  2. Establishing Normative Values for the Barnett Balance Assessment Tool: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Monica L. Cercone MSOTS


    Full Text Available The purpose of this study was to establish normative data for the Barnett Balance Assessment (BBA for individuals ages 18-70+ years. The BBA is a newly developed assessment tool that may address limitations present in other assessments currently used to detect balance deficits. The BBA was administered to 141 participants who had no history of medical issues that could impact balance. A review of the normative data collected indicated little variation in total assessment scores in the age categories of 18-29, 30-39, and 40-49, due to the presence of a ceiling effect. Variations existed in scores among participants in the remaining age categories (50-59, 60-69, and 70+. These findings may imply that the BBA has its greatest discriminative power in assessing individuals with impaired balance, and/or that the BBA is not sensitive enough to detect differences in individuals with mild balance impairments. The researchers suggest future studies be conducted with the BBA to establish norms with populations with known orthopedic or neurological conditions that may impair balance. Results of these studies could then be compared with the baseline data gathered in this study to determine the BBA’s usefulness in detecting balance impairments with clinical populations.

  3. Risk assessment of oil and gas well drilling activities in Iran - a case study: human factors. (United States)

    Amir-Heidari, Payam; Farahani, Hadi; Ebrahemzadih, Mehrzad


    Oil and gas well drilling activities are associated with numerous hazards which have the potential to cause injury or harm for people, property and the environment. These hazards are also a threat for the reputation of drilling companies. To prevent accidents and undesired events in drilling operations it is essential to identify, evaluate, assess and control the attendant risks. In this work, a structured methodology is proposed for risk assessment of drilling activities. A case study is performed to identify, analyze and assess the risks arising from human factors in one of the on shore drilling sites in southern Iran. A total of 17 major hazards were identified and analyzed using the proposed methodology. The results showed that the residual risks of 100% of these hazards were in the acceptable or transitional zone, and their levels were expected to be lowered further by proper controls. This structured methodology may also be used in other drilling sites and companies for assessing the risks.

  4. Retrospective exposure assessment and quality control in an international multi-centre case-control study

    DEFF Research Database (Denmark)

    Tinnerberg, H; Heikkilä, P; Huici-Montagud, A;


    The paper presents the exposure assessment method and quality control procedure used in an international, multi-centre case-control study within a joint Nordic and Italian cohort. This study was conducted to evaluate whether occupational exposure to carcinogens influenced the predictivity of high...... frequency of chromosomal aberrations (CA) in peripheral lymphocytes for increased cancer risk. Occupational hygienists assessed exposures in each participating country: Denmark, Finland, Italy, Norway and Sweden. The exposure status to a carcinogen or a clastogen was coded in the cohort according...... country-specific differences, differences in information available to the home assessor and the others and misunderstandings or difficulties in translation of information. To ensure the consistency of exposure assessments in international retrospective case-control studies it is important to have a well...


    Directory of Open Access Journals (Sweden)



    Full Text Available OBJECTIVE: The objective of this study was to compare the efficacy and safety of Valacyclovir and Famcyclovir in the management of Acute Herpes Zoster. MATERIALS AND METHODS: Relevant data were taken from 162 patients with herpes zoster who presented within 72 hours of onset of rash and were randomized into 2 groups of 81 each. The 1st group received Valacyclovir 1gm thrice a day for 7 days while those in the 2nd group received Famcyclovir 500 mg thrice a day for 7 days respectively and evaluated at the end of each week upto 6 weeks period and examined for full crusting of lesions, complete healing of the lesion and loss of acute pain (visual analogue scale scores for pain. Safety assessment was based on adverse effects. RESULTS: The intent to treat analysis (162 Pts showed that valacyclovir for 7 days significantly accelerated the resolution of pain in Herpes zoster pts (P=0.00014 compared with famcyclovir; median pain duration were 21 and 22 days respectively. There was no difference between treatments in time taken for healing of lesions. Adverse effects like nausea, vomiting, diarrhoea and headache were commonly reported in both groups. Valacyclovir was found to be statistically superior over Famcyclovir in terms of G.I adverse effects. Compliance was also better with Valacyclovir. CONCLUSION: Oral Valacyclovir administered three times daily for 7 days during acute zoster infection offers significant benefit by providing a well-tolerated, cost effective and accelerated rate of resolution of pain and maintains the favorable safety profile compared to oral Famcyclovir.

  6. Incorporating formative assessment and science content into elementary science methods---A case study (United States)

    Brower, Derek John

    Just as elementary students enter the science classroom with prior knowledge and experiences, so do preservice elementary teachers who enter the science methods classroom. Elementary science methods instructors recognize the challenges associated with preparing teachers for the science classroom. Two of these challenges include overcoming limited science content understanding and a low science teaching efficacy. Based upon research in science misconceptions, conceptual change theory, formative assessment, and science teaching efficacy, this design experiment explored the use of formative assessment in an authentic learning environment to address some of these challenges. As a case study, the goal was to identify two specific topics in science which the preservice teachers did not understand and to model consistent use of formative assessment to guide instruction in those science topics for six weeks. The research questions for this study sought to explore the design of the class while also exploring students' understanding of the science content and their understanding of formative assessment. One specific question was whether the formative data could differentiate between deeply held student misconceptions in science and incomplete science understanding. In addition, data was collected to measure changes in science teaching efficacy as well as preservice teachers' desire to use formative assessment in their own future classrooms. Based upon student interviews and a final content quiz, the participants in this study did show improved science content understanding in the areas of plant food/energy and plate tectonics. The course design implemented a variety of formative assessment tools including formative assessment probes, student science notebooks, student concept maps, a non-graded quiz, and more. The STEBI-B survey identified improved science teaching efficacy among the participants. Student final essays indicated improved understanding of formative assessment

  7. Final Report on Pilot Studies / Final Report on Classroom Research with STEM and TESL Assessment

    DEFF Research Database (Denmark)

    Biel, Carmen; Wake, Jo Dugstad; Hesse, Friedrich

    This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables.......This Deliverable is the final report on pilot studies within the NEXT-TELL project (D6.7) and furthermore comprises the Deliverable on Classroom Research with STEM and TESL Assessment (D2.9) in order to avoid redundancies between those two Deliverables....

  8. A method for quantitative assessment of artifacts in EEG, and an empirical study of artifacts. (United States)

    Kappel, Simon L; Looney, David; Mandic, Danilo P; Kidmose, Preben


    Wearable EEG systems for continuous brain monitoring is an emergent technology that involves significant technical challenges. Some of these are related to the fact that these systems operate in conditions that are far less controllable with respect to interference and artifacts than is the case for conventional systems. Quantitative assessment of artifacts provides a mean for optimization with respect to electrode technology, electrode location, electronic instrumentation and system design. To this end, we propose an artifact assessment method and evaluate it over an empirical study of 3 subjects and 5 different types of artifacts. The study showed consistent results across subjects and artifacts.

  9. Functional assessment of the Vanderbilt Multigrasp myoelectric hand: a continuing case study. (United States)

    Dalley, Skyler A; Bennett, Daniel A; Goldfarb, Michael


    This paper presents a case study involving the functional assessment of the Vanderbilt Multigrasp (VMG) hand prosthesis on a single transradial amputee subject. In particular, a transradial amputee subject performed the Southampton Hand Assessment Procedure (SHAP) using the hand prosthesis and multigrasp myoelectric controller in a series of experimental sessions occurring over a multi-week time span. The subject's index of function (IoF) improved with each session, although essentially plateaued after the fourth session, resulting in a IoF score of 87, which compares favorably to SHAP scores published in previous studies.

  10. Southeast Regional Assessment Study: an assessment of the opportunities of solar electric power generation in the Southeastern United States

    Energy Technology Data Exchange (ETDEWEB)



    The objective of this study was to identify and assess opportunities for demonstration and large scale deployment of solar electric facilities in the southeast region and to define the technical, economic, and institutional factors that can contribute to an accelerated use of solar energy for electric power generation. Graphs and tables are presented indicating the solar resource potential, siting opportunities, energy generation and use, and socioeconomic factors of the region by state. Solar electric technologies considered include both central station and dispersed solar electric generating facilities. Central stations studied include solar thermal electric, wind, photovoltaic, ocean thermal gradient, and biomass; dispersed facilities include solar thermal total energy systems, wind, and photovoltaic. The value of solar electric facilities is determined in terms of the value of conventional facilities and the use of conventional fuels which the solar facilities can replace. Suitable cost and risk sharing mechanisms to accelerate the commercialization of solar electric technologies in the Southeast are identified. The major regulatory and legal factors which could impact on the commercialization of solar facilities are reviewed. The most important factors which affect market penetration are reviewed, ways to accelerate the implementation of these technologies are identified, and market entry paths are identified. Conclusions and recommendations are presented. (WHK)

  11. Health Risk Assessment using in vitro digestion model in assessing bioavailability of heavy metal in rice: A preliminary study. (United States)

    Omar, N A; Praveena, S M; Aris, A Z; Hashim, Z


    Little is known about the bioavailability of heavy metal contamination and its health risks after rice ingestion. This study aimed to determine bioavailability of heavy metal (As, Cd, Cu, Cr, Co, Al, Fe, Zn and Pb) concentrations in cooked rice and human Health Risk Assessment (HRA). The results found Zn was the highest (4.3±0.1 mg/kg), whereas As showed the lowest (0.015±0.001 mg/kg) bioavailability of heavy metal concentration in 22 varieties of cooked rice. For single heavy metal exposure, no potential of non carcinogenic health risks was found, while carcinogenic health risks were found only for As. Combined heavy metal exposures found that total Hazard Quotient (HQtotal) values for adult were higher than the acceptable range (HQTotal1×10(-4)) for both adult and children. This study is done to understand that the inclusion of bioavailability heavy metal into HRA produces a more realistic estimation of human heavy metal exposure.

  12. Recommendations by Cochrane Review Groups for assessment of the risk of bias in studies

    Directory of Open Access Journals (Sweden)

    Gøtzsche Peter C


    Full Text Available Abstract Background Assessing the risk of bias in individual studies in a systematic review can be done using individual components or by summarizing the study quality in an overall score. Methods We examined the instructions to authors of the 50 Cochrane Review Groups that focus on clinical interventions for recommendations on methodological quality assessment of studies. Results Forty-one of the review groups (82% recommended quality assessment using components and nine using a scale. All groups recommending components recommended to assess concealment of allocation, compared to only two of the groups recommending scales (P Conclusion We found that recommendations by some groups were not based on empirical evidence and many groups had no recommendations on how to use the quality assessment in reviews. We suggest that all Cochrane Review Groups refer to the Cochrane Handbook for Systematic Reviews of Interventions, which is evidence-based, in their instructions to authors and that their own guidelines are kept to a minimum and describe only how methodological topics that are specific to their fields should be handled.

  13. Assessment of online marketing communications of an automotive company - A case study of Jaguar Cars, Sweden


    Bendzovska, Daniela; Blomqvist, Michelle; Rubenstein, Sara


    Over the years, the traditional face of marketing has changed. Companies need to adopt ongoing marketing strategies to stay ahead of their competitors; the design and content of their strategies continue to evolve. In this thesis a case study has been conducted on one company within the automotive industry in Sweden. The case study was performed on Jaguar Cars in Sweden and an assessment of their use of Online Marketing Communication (OMC) as a marketing tool was made. The case study indicat...

  14. Ultrasound Assessment of Umbilical Cord Morphology in the First Trimester: A Feasibility Study

    DEFF Research Database (Denmark)

    Narayan, Rajit; Saaid, Rahmah; Pedersen, Lars Henning


    Objective: The aim of this study was to determine whether morphology and measurement of the umbilical cord could be accurately assessed at the time of the 11- to 13+6-week scan. Methods: We conducted a prospective study of 100 consecutive women with singleton pregnancies at 11-13+6 weeks' gestation...... be consistently studied in the first trimester. A subjective method of evaluation of the morphology may be a more reproducible technique until measurement strategies are refined and operator experience developed....

  15. What is Learned from Longitudinal Studies of Advertising and Youth Drinking and Smoking? A Critical Assessment

    Directory of Open Access Journals (Sweden)

    Jon P. Nelson


    Full Text Available This paper assesses the methodology employed in longitudinal studies of advertising and youth drinking and smoking behaviors. These studies often are given a causal interpretation in the psychology and public health literatures. Four issues are examined from the perspective of econometrics. First, specification and validation of empirical models. Second, empirical issues associated with measures of advertising receptivity and exposure. Third, potential endogeneity of receptivity and exposure variables. Fourth, sample selection bias in baseline and follow-up surveys. Longitudinal studies reviewed include 20 studies of youth drinking and 26 studies of youth smoking. Substantial shortcomings are found in the studies, which preclude a causal interpretation.

  16. Qualichem in vivo: A tool for assessing the quality of in vivo studies and its application for bisphenol A

    NARCIS (Netherlands)

    Maxim, Laura; Van Der Sluijs, Jeroen P.


    In regulatory toxicology, quality assessment of in vivo studies is a critical step for assessing chemical risks. It is crucial for preserving public health studies that are considered suitable for regulating chemicals are robust. Current procedures for conducting quality assessments in safety agenci

  17. Reporting of Human Genome Epidemiology (HuGE association studies: An empirical assessment

    Directory of Open Access Journals (Sweden)

    Gwinn Marta


    Full Text Available Abstract Background Several thousand human genome epidemiology association studies are published every year investigating the relationship between common genetic variants and diverse phenotypes. Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies. Methods Articles were randomly selected from a continuously updated database of human genome epidemiology association studies to be representative of genetic epidemiology literature. The main analysis evaluated 315 articles published in 2001–2003. For a comparative update, we evaluated 28 more recent articles published in 2006, focusing on issues that were poorly reported in 2001–2003. Results During both time periods, most studies comprised relatively small study populations and examined one or more genetic variants within a single gene. Articles were inconsistent in reporting the data needed to assess selection bias and the methods used to minimize misclassification (of the genotype, outcome, and environmental exposure or to identify population stratification. Statistical power, the use of unrelated study participants, and the use of replicate samples were reported more often in articles published during 2006 when compared with the earlier sample. Conclusion We conclude that many items needed to assess error and bias in human genome epidemiology association studies are not consistently reported. Although some improvements were seen over time, reporting guidelines and online supplemental material may help enhance the transparency of this literature.

  18. Water Footprint and Life Cycle Assessment as approaches to assess potential impacts of products on water consumption: Key learning points from pilot studies on tea and margarine

    NARCIS (Netherlands)

    Jefferies, D.; Muñoz, I.; Hodges, J.; King, V.J.; Aldaya, M.M.; Ercin, A.E.; Milá i Canals, L.; Hoekstra, A.Y.


    Water accounting and environmental impact assessment across the product's life cycle is gaining prominence. This paper presents two case studies of applying the Life Cycle Assessment (LCA) and Water Footprint (WF) approaches to tea and margarine. The WF, excluding grey water, of a carton of 50 g tea

  19. Biomass Assessment. Assessment of global biomass potentials and their links to food, water, biodiversity, energy demand and economy. Inventory and analysis of existing studies. Supporting document

    Energy Technology Data Exchange (ETDEWEB)

    Dornburg, V.; Faaij, A.; Verweij, P. [Utrecht University, Utrecht (Netherlands); Banse, M.; Van Diepen, K.; Van Keulen, H.; Langeveld, H.; Meeusen, M.; Van de Ven, G.; Wester, F. [Wageningen UR, Wageningen (Netherlands); Alkemade, R.; Ten Brink, B.; Van den Born, G.J.; Van Oorschot, M.; Ros, J.; Smout, F.; Van Vuuren, D.; Van den Wijngaart, R. [Netherlands Environmental Assessment Agency NMP, Bilthoven (Netherlands); Aiking, H. [Vrije Universiteit, Amsterdam (Netherlands); Londo, M.; Mozaffarian, H.; Smekens, K. [ECN Policy Studies, Petten (Netherlands); Lysen, E. (ed.); Van Egmond, S. (ed.) [Utrecht Centre for Energy research UCE, Utrecht University, Utrecht (Netherlands)


    This supporting document contains the result from the inventory phase of the biomass assessment of global biomass potentials and their links to food, water, biodiversity, energy demand and economy. This study provides a comprehensive assessment of global biomass potential estimates, focusing on the various factors affecting these potentials, such as food supplies, water use, biodiversity, energy demands and agro-economics.

  20. International Code Assessment and Applications Program: Summary of code assessment studies concerning RELAP5/MOD2, RELAP5/MOD3, and TRAC-B. International Agreement Report

    Energy Technology Data Exchange (ETDEWEB)

    Schultz, R.R. [EG and G Idaho, Inc., Idaho Falls, ID (United States)


    Members of the International Code Assessment Program (ICAP) have assessed the US Nuclear Regulatory Commission (USNRC) advanced thermal-hydraulic codes over the past few years in a concerted effort to identify deficiencies, to define user guidelines, and to determine the state of each code. The results of sixty-two code assessment reviews, conducted at INEL, are summarized. Code deficiencies are discussed and user recommended nodalizations investigated during the course of conducting the assessment studies and reviews are listed. All the work that is summarized was done using the RELAP5/MOD2, RELAP5/MOD3, and TRAC-B codes.

  1. Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area

    Institute of Scientific and Technical Information of China (English)

    Tang Chuan; Zhu Jing; Liang Jingtao


    The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area. A numerical rating system was applied to five factors that contribute to slope instability. Factors such as lithology, topography, streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment. A final map is provided to show areas of low,medium, and high landslide susceptibility. Areas identified as having high landslide susceptibility were located in the central,northeastern, and far south regions of the study area. The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction. The maps may also be used as a basis for landslide risk management in the study area.

  2. Bone density assessment for evaluation of gender differences in cervical vertebral maturation: A computed tomography study (United States)

    Usha, K.; Baskaranarayanan, Balashanmugam; Nagarajan, D.; Selvarani, R.; Vijjaykanth, M.


    Introduction: The cervical vertebral maturation (CVM) method is a vital tool for assessing the biological maturation of the orthodontic patient to evaluate the amount of mandibular bone growth left. Aim: To assess and visualize the cervical vertebral morphology (bone density) of orthodontic patients of the age group 9,16,27 years. Material and Methods: Twenty four subjects with age group of 9,16,27 who were randomly selected and subjected to 3d tomographic study to estimate the biological age of the orthodontic patients by analyzing c1 c2 and c3 vertebrae. Result: The results showed that bone density of males is lesser than females in 9 and 16 years, whereas they have more bone density than females in 27 years. Conclusion: The study provides qualitative method of assessing the biological age of the patient by using images of cervical vertebrae by three dimensional approach. Hence it can be useful for orthodontic diagnosis and treatment plan. PMID:27829750

  3. Web-based Peer Assessment: A Case Study with Civil Engineering Students

    Directory of Open Access Journals (Sweden)

    Gonçalo Cruz


    Full Text Available Peer-assessed online collaborative writing is of growing importance for higher education. Based on the quantitative and qualitative analysis of collected data, this work presents the results of a case study in a graduate civil engineering course at the University of Trás-os-Montes e Alto Douro, Vila Real, Portugal. After an overall presentation of the learning activity, it examines students’ attitudes towards web-based peer assessment and identifies which factors are related to students’ use and appreciation of feedback. In addition, an analysis of the type of feedback is presented in an attempt to evaluate students’  written communication skills. The results of this study provide indications on how to improve the design and implementation of future web-based peer assessment tasks and raise questions on the effectiveness of peer/teacher grading in the use of feedback.

  4. Multi-Criteria Sustainability Assessment of Urban Sludge Treatment Technologies: Method and case study

    DEFF Research Database (Denmark)

    An, Da; Xi, Beidou; Ren, Jingzheng;


    This study aims at developing a sustainability assessment framework for assessing the technologies for the treatment of urban sewage sludge based on the logarithmic fuzzy preference programming based fuzzy analytic hierarchy process (LFPPFAHP) and extension theory. LFPPFAHP was employed...... to determine the weights of the criteria for sustainability assessment, and extension theory was used to prioritize the alternative technologies for the treatment of urban sewage sludge and grade their sustainability performances. An illustrative case including three technologies (compositing, incineration......, and resource utilization) was studied by the proposed method, and compositing, incineration, and resource utilization are recognized as "Moderately Sustainable", "Not Sustainable", and "Highly Sustainable", respectively. The sustainability sequence in the descending order is resource utilization, compositing...

  5. Bayesian hierarchical models combining different study types and adjusting for covariate imbalances: a simulation study to assess model performance.

    Directory of Open Access Journals (Sweden)

    C Elizabeth McCarron

    Full Text Available BACKGROUND: Bayesian hierarchical models have been proposed to combine evidence from different types of study designs. However, when combining evidence from randomised and non-randomised controlled studies, imbalances in patient characteristics between study arms may bias the results. The objective of this study was to assess the performance of a proposed Bayesian approach to adjust for imbalances in patient level covariates when combining evidence from both types of study designs. METHODOLOGY/PRINCIPAL FINDINGS: Simulation techniques, in which the truth is known, were used to generate sets of data for randomised and non-randomised studies. Covariate imbalances between study arms were introduced in the non-randomised studies. The performance of the Bayesian hierarchical model adjusted for imbalances was assessed in terms of bias. The data were also modelled using three other Bayesian approaches for synthesising evidence from randomised and non-randomised studies. The simulations considered six scenarios aimed at assessing the sensitivity of the results to changes in the impact of the imbalances and the relative number and size of studies of each type. For all six scenarios considered, the Bayesian hierarchical model adjusted for differences within studies gave results that were unbiased and closest to the true value compared to the other models. CONCLUSIONS/SIGNIFICANCE: Where informed health care decision making requires the synthesis of evidence from randomised and non-randomised study designs, the proposed hierarchical Bayesian method adjusted for differences in patient characteristics between study arms may facilitate the optimal use of all available evidence leading to unbiased results compared to unadjusted analyses.

  6. Using touch-screen technology to assess smoking in a low-income primary care clinic: a pilot study. (United States)

    Smith, Philip H; Homish, Gregory G; Barrick, Christopher; Grier, Nancy L


    This pilot study examined the use of a touch-screen tablet personal computer to assess smoking and alcohol use among low-income primary care patients (N = 100) and tested cross-method consistency with a paper assessment. Data were collected in 2009. A touch-screen survey assessed smoking, alcohol use, partner smoking, and acceptability. A separate paper survey assessed smoking, partner smoking, and acceptability. The touch-screen assessment was highly acceptable and reliable. Implications and limitations are noted. Future research should explore the use of touch-screen technology for clinical endeavors requiring a quick assessment of substance use. There was no outside funding for this study.

  7. Combining Learning and Assessment in Assessment-Based Gaming Environments: A Case Study from a New York City School (United States)

    Zapata-Rivera, Diego; VanWinkle, Waverely; Doyle, Bryan; Buteux, Alyssa; Bauer, Malcolm


    Purpose: The purpose of this paper is to propose and demonstrate an evidence-based scenario design framework for assessment-based computer games. Design/methodology/approach: The evidence-based scenario design framework is presented and demonstrated by using BELLA, a new assessment-based gaming environment aimed at supporting student learning of…

  8. Measuring Primary Students' Graph Interpretation Skills Via a Performance Assessment: A case study in instrument development (United States)

    Peterman, Karen; Cranston, Kayla A.; Pryor, Marie; Kermish-Allen, Ruth


    This case study was conducted within the context of a place-based education project that was implemented with primary school students in the USA. The authors and participating teachers created a performance assessment of standards-aligned tasks to examine 6-10-year-old students' graph interpretation skills as part of an exploratory research project. Fifty-five students participated in a performance assessment interview at the beginning and end of a place-based investigation. Two forms of the assessment were created and counterbalanced within class at pre and post. In situ scoring was conducted such that responses were scored as correct versus incorrect during the assessment's administration. Criterion validity analysis demonstrated an age-level progression in student scores. Tests of discriminant validity showed that the instrument detected variability in interpretation skills across each of three graph types (line, bar, dot plot). Convergent validity was established by correlating in situ scores with those from the Graph Interpretation Scoring Rubric. Students' proficiency with interpreting different types of graphs matched expectations based on age and the standards-based progression of graphs across primary school grades. The assessment tasks were also effective at detecting pre-post gains in students' interpretation of line graphs and dot plots after the place-based project. The results of the case study are discussed in relation to the common challenges associated with performance assessment. Implications are presented in relation to the need for authentic and performance-based instructional and assessment tasks to respond to the Common Core State Standards and the Next Generation Science Standards.

  9. Systematic review of foodborne burden of disease studies: quality assessment of data and methodology. (United States)

    Haagsma, Juanita A; Polinder, Suzanne; Stein, Claudia E; Havelaar, Arie H


    Burden of disease (BoD) studies aim to identify the public health impact of different health problems and risk factors. To assess BoD, detailed knowledge is needed on epidemiology, disability and mortality in the population under study. This is particularly challenging for foodborne disease, because of the multitude of causative agents and their health effects. The purpose of this study is to systematically review the methodology of foodborne BoD studies. Three key questions were addressed: 1) which data sources and approaches were used to assess mortality, morbidity and disability?, 2) which methodological choices were made to calculate Disability Adjusted Life Years (DALY), and 3) were uncertainty analyses performed and if so, how? Studies (1990-June 2012) in international peer-reviewed journals and grey literature were identified with main inclusion criteria being that the study assessed disability adjusted life years related to foodborne disease. Twenty-four studies met our inclusion criteria. To assess incidence or prevalence of foodborne disease in the population, four approaches could be distinguished, each using a different data source as a starting point, namely 1) laboratory-confirmed cases, 2) cohort or cross-sectional data, 3) syndrome surveillance data and 4) exposure data. Considerable variation existed in BoD methodology (e.g. disability weights, discounting, age-weighting). Almost all studies analyzed the effect of uncertainty as a result of possible imprecision in the parameter values. Awareness of epidemiological and methodological rigor between foodborne BoD studies using the DALY approach is a critical priority for advancing burden of disease studies. Harmonization of methodology that is used and of modeling techniques and high quality data can enlarge the detection of real variation in DALY outcomes between pathogens, between populations or over time. This harmonization can be achieved by identifying substantial data gaps and uncertainty and

  10. Deep assessment: an exploratory study of game-based, multimodal learning in Epidemic

    Directory of Open Access Journals (Sweden)

    Jennifer Jenson


    Full Text Available n this study, we examine what and how intermediate age students learned from playing in a health-focused game-based digital learning environment, Epidemic. Epidemic is a playful interactive environment designed to deliver factual knowledge, invite critical understanding, and encourage effective self-care practices in dealing with viral contagious diseases, using a social networking interface to integrate both serious games and game-like multimodal design projects. Epidemic invites a playful approach to its deadly serious core concern – communicable disease – in order to see what happens when students are encouraged to critically approach information from multiple or contradictory perspectives. To identify what participants learned while interacting within Epidemic, we deployed two instructional and assessment models, noting the differences each instructional approach could potentially make, and what approach to assessment might help us evaluate game-based learning. We found that each approach provided importantly different perspectives on what and how students learned, and on the very meaning of student success. Recognizing that traditional assessment tools based in print-cultural literacy may prove increasingly ill-suited for assessing emergent multimodal literacies in game-based learning environments, this study seeks to contribute to a growing body of work on the development of novel assessments for learning.

  11. The human component of sustainability: a study for assessing "human performances" of energy efficient construction blocks. (United States)

    Attaianese, Erminia; Duca, Gabriella


    This paper presents an applied research aimed at understanding the relevance and the applicability of human related criteria in sustainability assessment of construction materials. Under a theoretical perspective, human factors consideration is strongly encouraged by building sustainability assessment methods, but the practice demonstrates that current models for building sustainability assessment neglect ergonomic issues, especially those ones concerning the construction phase. The study starts from the observation that new construction techniques for high energy efficient external walls are characterized by elements generally heavier and bigger than traditional materials. In this case, high sustainability performances connected with energy saving could be reached only consuming high, and then not very much sustainable, human efforts during setting-up operations. The paper illustrates a practical approach for encompassing human factors in sustainability assessment of four block types for energy efficient external walls. Research steps, from block selections to bricklaying task analysis, human factors indicators and metrics formulation, data gathering and final assessment are going to be presented. Finally, open issues and further possible generalizations from the particular case study will be discussed.

  12. A review of studies applying environmental impact assessment methods on fruit production systems. (United States)

    Cerutti, Alessandro K; Bruun, Sander; Beccaro, Gabriele L; Bounous, Giancarlo


    Although many aspects of environmental accounting methodologies in food production have already been investigated, the application of environmental indicators in the fruit sector is still rare and no consensus can be found on the preferred method. On the contrary, widely diverging approaches have been taken to several aspects of the analyses, such as data collection, handling of scaling issues, and goal and scope definition. This paper reviews studies assessing the sustainability or environmental impacts of fruit production under different conditions and identifies aspects of fruit production that are of environmental importance. Four environmental assessment methods which may be applied to assess fruit production systems are evaluated, namely Life Cycle Assessment, Ecological Footprint Analysis, Emergy Analysis and Energy Balance. In the 22 peer-reviewed journal articles and two conference articles applying one of these methods in the fruit sector that were included in this review, a total of 26 applications of environmental impact assessment methods are described. These applications differ concerning e.g. overall objective, set of environmental issues considered, definition of system boundaries and calculation algorithms. Due to the relatively high variability in study cases and approaches, it was not possible to identify any one method as being better than the others. However, remarks on methodologies and suggestions for standardisation are given and the environmental burdens of fruit systems are highlighted.

  13. Assessment of stereoscopic optic disc images using an autostereoscopic screen – experimental study

    Directory of Open Access Journals (Sweden)

    Vaideanu Daniella


    Full Text Available Abstract Background Stereoscopic assessment of the optic disc morphology is an important part of the care of patients with glaucoma. The aim of this study was to assess stereoviewing of stereoscopic optic disc images using an example of the new technology of autostereoscopic screens compared to the liquid shutter goggles. Methods Independent assessment of glaucomatous disc characteristics and measurement of optic disc and cup parameters whilst using either an autostereoscopic screen or liquid crystal shutter goggles synchronized with a view switching display. The main outcome measures were inter-modality agreements between the two used modalities as evaluated by the weighted kappa test and Bland Altman plots. Results Inter-modality agreement for measuring optic disc parameters was good [Average kappa coefficient for vertical Cup/Disc ratio was 0.78 (95% CI 0.62–0.91 and 0.81 (95% CI 0.6–0.92 for observer 1 and 2 respectively]. Agreement between modalities for assessing optic disc characteristics for glaucoma on a five-point scale was very good with a kappa value of 0.97. Conclusion This study compared two different methods of stereo viewing. The results of assessment of the different optic disc and cup parameters were comparable using an example of the newly developing autostereoscopic display technologies as compared to the shutter goggles system used. The Inter-modality agreement was high. This new technology carries potential clinical usability benefits in different areas of ophthalmic practice.

  14. Improvement of agricultural life cycle assessment studies through spatial differentiation and new impact categories: case study on greenhouse tomato production. (United States)

    Antón, Assumpció; Torrellas, Marta; Núñez, Montserrat; Sevigné, Eva; Amores, Maria José; Muñoz, Pere; Montero, Juan I


    This paper presents the inclusion of new, relevant impact categories for agriculture life cycle assessments. We performed a specific case study with a focus on the applicability of spatially explicit characterization factors. The main goals were to provide a detailed evaluation of these new impact category methods, compare the results with commonly used methods (ReCiPe and USEtox) and demonstrate how these new methods can help improve environmental assessment in agriculture. As an overall conclusion, the newly developed impact categories helped fill the most important gaps related to land use, water consumption, pesticide toxicity, and nontoxic emissions linked to fertilizer use. We also found that including biodiversity damage due to land use and the effect of water consumption on wetlands represented a scientific advance toward more realistic environmental assessment of agricultural practices. Likewise, the dynamic crop model for assessing human toxicity from pesticide residue in food can lead to better practice in pesticide application. In further life cycle assessment (LCA) method developments, common end point units and normalization units should be agreed upon to make it possible to compare different impacts and methods. In addition, the application of site-specific characterization factors allowed us to be more accurate regarding inventory data and to identify precisely where background flows acquire high relevance.

  15. Alcohol email assessment and feedback study dismantling effectiveness for university students (AMADEUS-1: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    McCambridge Jim


    Full Text Available Abstract Background Alcohol causes huge problems for population health and for society, which require interventions with individuals as well as populations to prevent and reduce harms. Brief interventions can be effective and increasingly take advantage of the internet to reach high-risk groups such as students. The research literature on the effectiveness of online interventions is developing rapidly and is confronted by methodological challenges common to other areas of e-health including attrition and assessment reactivity and in the design of control conditions. Methods/design The study aim is to evaluate the effectiveness of a brief online intervention, employing a randomized controlled trial (RCT design that takes account of baseline assessment reactivity, and other possible effects of the research process. Outcomes will be evaluated after 3 months both among student populations as a whole including for a randomized no contact control group and among those who are risky drinkers randomized to brief assessment and feedback (routine practice or to brief assessment only. A three-arm parallel groups trial will also allow exploration of the magnitude of the feedback and assessment component effects. The trial will be undertaken simultaneously in 2 universities randomizing approximately 15,300 students who will all be blinded to trial participation. All participants will be offered routine practice intervention at the end of the study. Discussion This trial informs the development of routine service delivery in Swedish universities and more broadly contributes a new approach to the study of the effectiveness of online interventions in student populations, with relevance to behaviors other than alcohol consumption. The use of blinding and deception in this study raise ethical issues that warrant further attention. Trial registration ISRCTN28328154

  16. An Assessment of Intervention Fidelity in Published Social Work Intervention Research Studies (United States)

    Corley, Nicole A.; Kim, Irang


    Objectives: Intervention fidelity is a critical strategy to help advance the usefulness and integrity of social work research. This study assessed the extent to which a selected sample of published social work intervention researchers reported its intervention protocols. Methods: Six core social work journals were reviewed in this analysis. The…

  17. A Normative Study of the Person Picking an Apple from a Tree (PPAT) Assessment (United States)

    Bucciarelli, Amy


    The Person Picking an Apple from a Tree (PPAT) is an art therapy assessment task that is scored using the Formal Elements Art Therapy Scale (FEATS) to identify a client's mental health symptoms and progress in art therapy. Normative data are needed to empirically validate assumptions about the PPAT. This report summarizes a normative study of the…

  18. Evidence Based Assessment of Public Health Planning: A Case Study of the 2014 Crisis in Ukraine (United States)


    Assessment of Public Health Planning: A Case Study of the 2014 Crisis in Ukraine 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...armed conflict. As a result of the crisis , health care infrastructure was destroyed, health care workers fled, migrating patterns of vulnerable

  19. Health Workforce Development: A Needs Assessment Study in French Speaking African Countries (United States)

    Chastonay, Philippe; Moretti, Roberto; Zesiger, Veronique; Cremaschini, Marco; Bailey, Rebecca; Pariyo, George; Kabengele, Emmanuel Mpinga


    In 2006, WHO alerted the world to a global health workforce crisis, demonstrated through critical shortages of health workers, primarily in Sub-Saharan Africa (WHO in World Health Report, 2006). The objective of our study was to assess, in a participative way, the educational needs for public health and health workforce development among potential…

  20. 77 FR 29667 - Proposed Collection; Comment Request; Population Assessment of Tobacco and Health (PATH) Study (United States)


    ...: Population Assessment of Tobacco and Health (PATH) Study. Type of Information Collection Request: NEW. Need... mandate under the Family Smoking Prevention and Tobacco Control Act (FSPTCA) to regulate tobacco-product advertising, labeling, marketing, constituents, ingredients, and additives. These regulatory changes...

  1. Beyond speculative robot ethics: A vision assessment study on the future of the robotic caretaker

    NARCIS (Netherlands)

    Plas, A.P. van der; Smits, M.; Wehrmann, C.


    In this article we develop a dialogue model for robot technology experts and designated users to discuss visions on the future of robotics in long-term care. Our vision assessment study aims for more distinguished and more informed visions on future robots. Surprisingly, our experiment also led to s

  2. Effect of Continuous Assessment on Learning Outcomes on Two Chemical Engineering Courses: Case Study (United States)

    Tuunila, R.; Pulkkinen, M.


    In this paper, the effect of continuous assessment on the learning outcomes of two chemical engineering courses is studied over a several-year period. Average grades and passing percentages of courses after the final examination are reported and also student feedback on the courses is collected. The results indicate significantly better learning…

  3. Assessment of thermal sensitivity of CT during heating of liver : an ex vivo study

    NARCIS (Netherlands)

    Pandeya, G. D.; Greuter, M. J. W.; Schmidt, B.; Flohr, T.; Oudkerk, M.


    Objectives: The purpose of this study was to assess the thermal sensitivity of CT during heating of ex-vivo animal liver. Methods: Pig liver was indirectly heated from 20 to 90 degrees C by passage of hot air through a plastic tube. The temperature in the heated liver was measured using calibrated t

  4. Cumulative versus end-of-course assessment : effects on self-study time and test performance

    NARCIS (Netherlands)

    Kerdijk, Wouter; Cohen-Schotanus, Janke; Mulder, B. Florentine; Muntinghe, Friso L. H.; Tio, Rene A.


    ContextStudents tend to postpone preparation for a test until the test is imminent, which raises various risks associated with cramming' behaviours, including that for suboptimal learning. Cumulative assessment utilises spaced testing to stimulate students to study more frequently and to prevent pro

  5. HEFCE's People Management Self-Assessment Tool: Ticking Boxes or Adding Value? A Case Study (United States)

    McDonald, Claire


    This article examines one specific organisational development tool in depth and uses a case study to investigate whether using the tool is more than a tick-box exercise and really can add value and help organisations to develop and improve. The People Management Self-Assessment Tool (SAT) is used to examine higher education institutions' (HEIs)…

  6. Has Portfolio Assessment Become Common Practice in EFL Classrooms? Empirical Studies from China (United States)

    Zhang, Shumei


    This paper describes the results of an investigation into the use of portfolio assessment (PA) in Chinese context, beginning with a survey of the rationale for the use of portfolios with students. Then the empirical study is presented and the teachers' and the students' as well as the English teaching advisors' voices are revealed through excerpts…

  7. Spatial variation in lake benthic macroinvertebrate ecological assessment: a synthesis of European case studies

    DEFF Research Database (Denmark)

    Sandin, Leif Leonard; Solimini, Angelo G.


    This paper summarizes eight case studies that were analysed as part of the research theme ``lake benthic macroinvertebrates'' forming part of the EU-funded WISER project ``Water bodies in Europe: Integrative Systems to assess Ecological status and Recovery''. The relationships between lake benthi...

  8. Preferences for Deep-Surface Learning: A Vocational Education Case Study Using a Multimedia Assessment Activity (United States)

    Hamm, Simon; Robertson, Ian


    This research tests the proposition that the integration of a multimedia assessment activity into a Diploma of Events Management program promotes a deep learning approach. Firstly, learners' preferences for deep or surface learning were evaluated using the revised two-factor Study Process Questionnaire. Secondly, after completion of an assessment…

  9. Using the Internship as a Tool for Assessment: A Case Study. (United States)

    Graham, Beverly; Bourland-Davis, Pamela G.; Fulmer, Hal W.


    States communication programs are expected to operate in some harmony with communication activities of organizations outside the university in professional settings. Describes one possible activity in this matrix: use of student internships as a means of assessing the communication program. Presents a case study involving public relations…

  10. Initiating Self-Assessment Strategies in Novice Physiotherapy Students: A Method Case Study (United States)

    Young, Catherine


    Student self- and peer-assessment strategies ideally are instigated early in programmes for health professionals. This study presents an innovative method of stimulating critical evaluation of clinical skills learned in the practical class setting for first year physiotherapy students. Twice in the semester (beginning and end) students assessed…

  11. Comparative study of anal acoustic reflectometry and anal manometry in the assessment of faecal incontinence

    DEFF Research Database (Denmark)

    Hornung, B R; Mitchell, P J; Carlson, G L;


    Anal acoustic reflectometry (AAR) is a reproducible technique providing a novel physiological assessment of anal sphincter function. It may have advantages over conventional anal manometry. The aims of this study were to determine the ability of AAR and anal manometry to identify changes in anal...

  12. Swallowing difficulties in Duchenne muscular dystrophy: indications for feeding assessment and outcome of videofluroscopic swallow studies

    DEFF Research Database (Denmark)

    Aloysius, A.; Born, P.; Kinali, M.


    Feeding difficulties are known to occur with advancing age in Duchenne muscular dystrophy (DMD). We evaluated the role of videofluoroscopy swallow study (VFSS) in a group of 30 DMD patients with feeding difficulties. Indications for feeding assessment were: respiratory infections potentially...

  13. Chair Report Consultancy Meeting on Nuclear Security Assessment Methodologies (NUSAM) Transport Case Study Working Group

    Energy Technology Data Exchange (ETDEWEB)

    Shull, Doug [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    The purpose of the consultancy assignment was to (i) apply the NUSAM assessment methods to hypothetical transport security table top exercise (TTX) analyses and (ii) document its results to working materials of NUSAM case study on transport. A number of working group observations, using the results of TTX methodologies, are noted in the report.

  14. The Effectiveness of Coursework Assessment in Mathematics Service Courses--Studies at Two Universities. (United States)

    Jackman, Susan; Goldfinch, Judy; Searl, John


    Describes the introduction and evaluation of the effectiveness of a single group project given at a new university, and 10 individual tasks at an ancient university, to devise appropriate and relevant assessments for first-year service mathematics courses for science and engineering. Studies the effects of these tasks on attitudes toward…

  15. Mood disorders in everyday life : A systematic review of experience sampling and ecological momentary assessment studies

    NARCIS (Netherlands)

    Aan het Rot, M.; Hogenelst, Koen; Schoevers, R.A.


    In the past two decades, the study of mood disorder patients using experience sampling methods (ESM) and ecological momentary assessment (EMA) has yielded important findings. In patients with major depressive disorder (MDD), the dynamics of their everyday mood have been associated with various aspec

  16. Validation of a Computerized Cognitive Assessment System for Persons with Stroke: A Pilot Study (United States)

    Yip, Chi Kwong; Man, David W. K.


    This study investigates the validity of a newly developed computerized cognitive assessment system (CCAS) that is equipped with rich multimedia to generate simulated testing situations and considers both test item difficulty and the test taker's ability. It is also hypothesized that better predictive validity of the CCAS in self-care of persons…

  17. Comparative assessment of predictions in ungauged basins – Part 2: Flood and low flow studies

    Directory of Open Access Journals (Sweden)

    J. L. Salinas


    Full Text Available The objective of this paper is to assess the performance of methods that predict low flows and flood runoff in ungauged catchments. The aim is to learn from the similarities and differences between catchments in different places, and to interpret the differences in performance in terms of the underlying climate-landscape controls. The assessment is performed at two levels. The Level 1 assessment is a meta-analysis of 14 low flow prediction studies reported in the literature involving 3112 catchments, and 20 flood prediction studies involving 3023 catchments. The Level 2 assessment consists of a more focused and detailed analysis of individual basins from selected studies from Level 1 in terms of how the leave-one-out cross-validation performance depends on climate and catchment characteristics as well as on the regionalisation method. The results indicate that both flood and low flow predictions in ungauged catchments tend to be less accurate in arid than in humid climates and more accurate in large than in small catchments. There is also a tendency towards a somewhat lower performance of regressions than other methods in those studies that apply different methods in the same region, while geostatistical methods tend to perform better than other methods. Of the various flood regionalisation approaches, index methods show significantly lower performance in arid catchments than regression methods or geostatistical methods. For low flow regionalisation, regional regressions are generally better than global regressions.

  18. Assessment of Greek University Students' Counselling Needs and Attitudes: An Exploratory Study (United States)

    Giovazolias, Theodoros; Leontopoulou, Sophia; Triliva, Sophia


    The present study is concerned with an exploration of counselling needs of students at two Greek universities as well as their attitudes to utilizing a university counselling centre. The sample consisted of 312 students who completed a Greek version of the Rutgers Needs Assessment Questionnaire as well as a subscale on Attitudes towards the…

  19. Form follows function? Proposing a blueprint for ecosystem service assessments based on reviews and case studies

    NARCIS (Netherlands)

    Seppelt, R.; Fath, B.; Burkhard, B.; Fisher, J.L.; Grêt-Regamey, A.; Lautenbach, S.; Pert, P.; Hotes, S.; Spangenberg, J.; Verburg, P.H.; Oudenhoven, van A.P.E.


    Ecosystem service assessments (ESA) hold the promise of supporting the quantification and valuation of human appropriation of nature and its goods and services. The concept has taken flight with the number of studies published on the topic increasing rapidly. This development, and the variation of d

  20. German Studies in the United States: Assessment and Outlook. Monatshefte Occasional Volume Number 1. (United States)

    Lohnes, Walter F. W., Ed.; Nollendorfs, Valters, Ed.

    This volume focuses on two principal aspects of German studies in the United States: (1) an assessment of the German-teaching profession from primary to graduate school, with attention to its "raison d'etre" in the present academic, social, and cultural situation, as well as its structures, aims, and personnel; and (2) strategies for survival and…

  1. Climate change impact assessment of extreme precipitation on urban flash floods – case study, Aarhus, Denmark

    DEFF Research Database (Denmark)

    Madsen, Henrik; Sunyer Pinya, Maria Antonia; Rosbjerg, Dan;

    Climate change is expected to cause more intense extreme rainfall events, which will have a severe impact on the risk of flash floods in urban areas. An assessment study was performed for the city of Aarhus, Denmark, analysing different methods of statistical downscaling of climate model...

  2. Perceptions of Effectiveness, Fairness and Feedback of Assessment Methods: A Study in Higher Education (United States)

    Flores, Maria Assunção; Veiga Simão, Ana Margarida; Barros, Alexandra; Pereira, Diana


    This paper draws upon a broader piece of research aimed at investigating assessment in higher education. It focuses upon the perceptions of undergraduates about issues of effectiveness, fairness and feedback, particularly in regard to the so-called learner-centred methods. In total, 378 undergraduate students participated in the study at the…

  3. A National Study of Teaching and Assessing Writing in Canadian Middle Grades Classrooms (United States)

    Peterson, Shelley Stagg; McClay, Jill


    This article reports comprehensive findings from a national study of the teaching and assessment of writing in classrooms across ten Canadian provinces and two of three territories. Through interviews with 216 grade 4-8 teachers and observations and interviews in 22 classrooms (1 to 3 classrooms in each province), we gathered information about…

  4. Evaluability Assessment Thesis and Dissertation Studies in Graduate Professional Degree Programs (United States)

    Walser, Tamara M.; Trevisan, Michael S.


    Evaluability assessment (EA) has potential as a design option for thesis and dissertation studies, serving as a practical training experience for both technical and nontechnical evaluation skills. Based on a content review of a sample of EA theses and dissertations from graduate professional degree programs, the authors of this article found that…

  5. 75 FR 33324 - MMS Information Collection Activity: 1010-NEW, Study of Sharing To Assess Community Resilience... (United States)


    ... Federal Register notice (75 FR 1648) announcing that we would submit this ICR to OMB for approval. The... Minerals Management Service MMS Information Collection Activity: 1010--NEW, Study of Sharing To Assess... collection (1010--NEW). SUMMARY: To comply with the Paperwork Reduction Act of 1995 (PRA), we are...

  6. A Study on Critical Thinking Assessment System of College English Writing (United States)

    Dong, Tian; Yue, Lu


    This research attempts to discuss the validity of introducing the evaluation of students' critical thinking skills (CTS) into the assessment system of college English writing through an empirical study. In this paper, 30 College English Test Band 4 (CET-4) writing samples were collected and analyzed. Students' CTS and the final scores of collected…

  7. The reliability of assessing rotation of teeth on photographed study casts

    NARCIS (Netherlands)

    Vermeulen, F.M.J.; Aartman, I.H.A.; Kuitert, R.; Zentner, A.


    Objective: To examine the intra- and interexaminer reliability of assessing rotation of teeth on photographed study casts. In addition, the reliability parameters of two examiners scoring in mutual consultation were compared with the reliability parameters by one observer. Materials and Methods: Sta

  8. Emotional Competencies in Geriatric Nursing: Empirical Evidence from a Computer Based Large Scale Assessment Calibration Study (United States)

    Kaspar, Roman; Hartig, Johannes


    The care of older people was described as involving substantial emotion-related affordances. Scholars in vocational training and nursing disagree whether emotion-related skills could be conceptualized and assessed as a professional competence. Studies on emotion work and empathy regularly neglect the multidimensionality of these phenomena and…

  9. Does Participation in Citizen Science Improve Scientific Literacy? A Study to Compare Assessment Methods (United States)

    Cronje, Ruth; Rohlinger, Spencer; Crall, Alycia; Newman, Greg


    This study investigated the use of a contextually sensitive instrument to assess the effect of invasive species monitoring training on the scientific literacy of citizen volunteers. The authors measured scientific literacy scores before and after 57 citizens participated in a 2-day event to learn to monitor invasive species with an instrument…

  10. What about Language while Equitably Assessing Science?: Case Studies of Preservice Teachers' Evolving Expertise (United States)

    Lyon, Edward G.


    The three case studies, drawing on qualitative analysis of surveys, interviews, program artifacts, and classroom observation, describe secondary science preservice teachers' evolving expertise at providing opportunities for linguistically diverse students to learn and demonstrate what they have learned (i.e., equitable assessment). The teachers…

  11. Individualizing Elementary General Music Instruction: Case Studies of Assessment and Differentiation (United States)

    Salvador, Karen


    Elementary general music teachers typically teach hundreds of students every week. Each child has individual learning needs due to a variety of factors, such as prior experiences with music, music aptitude, learning style, and personality. The purpose of this qualitative study was to explore ways that experienced teachers used assessments to…

  12. The Reflective Model of Intercultural Competency: A Multidimensional, Qualitative Approach to Study Abroad Assessment (United States)

    Williams, Tracy Rundstrom


    Judging from the recent surge in research on outcomes assessment, many study abroad offices rely on quantitative surveys and measures to collect student outcomes data. This paper presents a multidimensional, qualitative approach to data collection. This approach makes qualitative data easy to collect and encourages students to reflect and…

  13. Assessment of visuospatial neglect in stroke patients using virtual reality: a pilot study.

    NARCIS (Netherlands)

    Jannink, Michiel J.A.; Aznar, Miguel; Kort, de Alexander Cornelis; Vis, van de Wim; Veltink, Peter; Kooij, van der Herman


    One of the neuropsychological deficits that can result from a stroke is the neglect phenomenon. Neglect has traditionally been assessed with paper-and-pencil tasks, which are administered within the reaching space of a person. The purpose of this explorative study is to investigate whether it is pos

  14. Assessing internet addiction using the parsimonious internet addiction components model—A preliminary study.

    NARCIS (Netherlands)

    Kuss, D.J.; Shorter, G.W.; Rooij, A.J. van; Griffiths, M.D.; Schoenmakers, T.M.


    Internet usage has grown exponentially over the last decade. Research indicates that excessive Internet use can lead to symptoms associated with addiction. To date, assessment of potential Internet addiction has varied regarding populations studied and instruments used, making reliable prevalence es

  15. Success in the US: Are Cambridge International Assessments Good Preparation for University Study? (United States)

    Shaw, Stuart; Bailey, Clare


    This article focuses on the research being conducted by University of Cambridge International Examinations (Cambridge) to ensure that its international assessments prepare students as well as Advanced Placement and International Baccalaureate for continued studies in colleges and universities. The primary purpose of the research is to highlight…

  16. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review. (United States)

    Samuel, Gbeminiyi O; Hoffmann, Sebastian; Wright, Robert A; Lalu, Manoj Mathew; Patlewicz, Grace; Becker, Richard A; DeGeorge, George L; Fergusson, Dean; Hartung, Thomas; Lewis, R Jeffrey; Stephens, Martin L


    Assessments of methodological and reporting quality are critical to adequately judging the credibility of a study's conclusions and to gauging its potential reproducibility. To aid those seeking to assess the methodological or reporting quality of studies relevant to toxicology, we conducted a scoping review of the available guidance with respect to four types of studies: in vivo and in vitro, (quantitative) structure-activity relationships ([Q]SARs), physico-chemical, and human observational studies. Our aims were to identify the available guidance in this diverse literature, briefly summarize each document, and distill the common elements of these documents for each study type. In general, we found considerable guidance for in vivo and human studies, but only one paper addressed in vitro studies exclusively. The guidance for (Q)SAR studies and physico-chemical studies was scant but authoritative. There was substantial overlap across guidance documents in the proposed criteria for both methodological and reporting quality. Some guidance documents address toxicology research directly, whereas others address preclinical research generally or clinical research and therefore may not be fully applicable to the toxicology context without some translation. Another challenge is the degree to which assessments of methodological quality in toxicology should focus on risk of bias - as in clinical medicine and healthcare - or be broadened to include other quality measures, such as confirming the identity of test substances prior to exposure. Our review is intended primarily for those in toxicology and risk assessment seeking an entry point into the extensive and diverse literature on methodological and reporting quality applicable to their work.

  17. Assessing Researcher Interdisciplinarity: A Case Study of the University of Hawaii NASA Astrobiology Institute

    CERN Document Server

    Gowanlock, Michael G


    In this study, we combine bibliometric techniques with a machine learning algorithm, the sequential Information Bottleneck, to assess the interdisciplinarity of research produced by the University of Hawaii NASA Astrobiology Institute (UHNAI). In particular, we cluster abstract data to evaluate Thomson Reuters Web of Knowledge subject categories as descriptive labels for astrobiology documents, assess individual researcher interdisciplinarity, and determine where collaboration opportunities might occur. We find that the majority of the UHNAI team is engaged in interdisciplinary research, and suggest that our method could be applied to additional NASA Astrobiology Institute teams in particular, or other interdisciplinary research teams more broadly, to identify and facilitate collaboration opportunities.

  18. Retrospective study on the dose assessment in Algeria over a period 1998-2002

    Energy Technology Data Exchange (ETDEWEB)

    Boudena, B.; Chalal, M.; Bellal, A.; Imatoukene, D. [Nuclear Research Center of Algiers (Algeria)


    Full text: In Algeria, the assessment of individual doses of workers occupationally exposed to external radiations is made by the national individual monitoring service at the Nuclear Research Center of Algiers (N.R.C.A.) with photographic dosimeter. In this paper, we have undertaken a retrospective study on dose assessment of workers exposed to external radiations involved in medical and industrial activities according to the new occupational dose limits over a period of five consecutive years (1998 2002). This survey has permitted to observe the impact that would have new dose limits once adopted by our legislation. (author)

  19. Comparative assessment of antimicrobial efficacy of different hand sanitizers: An in vitro study


    Jain, Vardhaman Mulchand; Karibasappa, Gundabaktha Nagappa; Dodamani, Arun Suresh; Prashanth, Vishwakarma K.; Mali, Gaurao Vasant


    Background: To evaluate the antimicrobial efficacy of four different hand sanitizers against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Enterococcus faecalis as well as to assess and compare the antimicrobial effectiveness among four different hand sanitizers. Materials and Methods: The present study is an in vitro study to evaluate antimicrobial efficacy of Dettol, Lifebuoy, PureHands, and Sterillium hand sanitizers against clinical isola...

  20. Comparative assessment of antimicrobial efficacy of different hand sanitizers: An in vitro study


    Vardhaman Mulchand Jain; Gundabaktha Nagappa Karibasappa; Arun Suresh Dodamani; Prashanth, Vishwakarma K.; Gaurao Vasant Mali


    Background: To evaluate the antimicrobial efficacy of four different hand sanitizers against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Enterococcus faecalis as well as to assess and compare the antimicrobial effectiveness among four different hand sanitizers. Materials and Methods: The present study is an in vitro study to evaluate antimicrobial efficacy of Dettol, Lifebuoy, PureHands, and Sterillium hand sanitizers against clinical i...

  1. Environmental hot spot analysis in agricultural lifecycle assessments – three case studies


    PIRINGER, Gerhard; Bauer, Alexander; Gronauer, Andreas; SAYLOR, Molly Katherine; STAMPFEL, Angelika; KRAL, Iris


    Present-day agricultural technology is facing the challenge of limiting the environmental impacts of agricultural production – such as greenhouse gas emissions and demand for additional land – while meeting growing demands for agricultural products. Using the well-established method of life-cycle assessment (LCA), potential environmental impacts of agricultural production chains can be quantified and analyzed. This study presents three case studies of how the method can pinpoint environmental...

  2. Environmental hot spot analysis in agricultural life-cycle assessments – three case studies


    Gerhard Piringer; Alexander Bauer; Andreas Gronauer; Molly Saylor; Angelika Stampfel; Iris Kral


    Present-day agricultural technology is facing the challenge of limiting the environmental impacts of agricultural production – such as greenhouse gas emissions and demand for additional land – while meeting growing demands for agricultural products. Using the well-established method of life-cycle assessment (LCA), potential environmental impacts of agricultural production chains can be quantified and analyzed. This study presents three case studies of how the method can pinpoint environmental...

  3. Assessing Student Learning Outcomes from Reference Desk Interactions in an Academic Library: An Exploratory Study


    McCarthy, Patrick


    This paper presents the results of a preliminary study designed to examine the feasibility of conducting research into the learning outcomes associated with research consultation between reference librarians and university students. The researcher studied the teaching taking place at an academic library reference desk and assessed the student’s ability to apply what was taught to a new information need. The results indicate that participant awareness of library resources increased and their s...



    Lohith, B. A.; Girish K.J


    Gridhrasi is one of the most common disorders of Vata and frequently physician is called upon to manage painful condition in clinical practice. Symptoms of Gridhrasi simulate with Sciatica. The present ‘Clinical study was carried out to assess effect of yoga Basti in Gridhrasi. As Bastikarma is the most important among the Panchakarma for the management of Vatavyadi. In this clinical study, 10 patients received one sitting of yoga Basti, where five Anuvasana basti with the Sahacharadi taila a...

  5. Study of Validity, Reliability in Accordance with Turkey Conditions in Ego Functions Assessment Scale


    Çevik, Yadigar; Ünsal Barlas, Gül


    Objective: In schizophrenia, evaluating ego functions such as disintegration of thought processes, sexual or aggressive behaviour, insufficient occur in various settings. The Ego Function Assessment (EFA) Scale developed by Bellak (1973) allows identifying which ego function is associated with the problematic behaviour and determining the level of function disturbance in patients with schizophrenia. The present study aimed to conduct the validation, reliability and norm study for Ego Function...

  6. A Study of The diagnosis assessment On Developmental Disorders and Reactive attachment disorders.


    吉田, ゆり; 若本, 純子


    On the other hand of attention to developmental disorders, diagnosis and evaluation of developmental disabilities easy has been a concern. In this paper, given an overview of current diagnostic criteria, diagnostic aid tool, a measure of a structured interview.A preliminary study about the tool structured interviews to clarify autism spectrum is suspected, that specializes in assessment of Psychology preliminary study was carried out for development.

  7. Assessing internet addiction using the parsimonious internet addiction components model—A preliminary study.


    Kuss, D.J.; Shorter, G. W.; Rooij, A.J. van; Griffiths, M.D.; Schoenmakers, T.M.


    Internet usage has grown exponentially over the last decade. Research indicates that excessive Internet use can lead to symptoms associated with addiction. To date, assessment of potential Internet addiction has varied regarding populations studied and instruments used, making reliable prevalence estimations difficult. To overcome the present problems a preliminary study was conducted testing a parsimonious Internet addiction components model based on Griffiths’ addiction components (Journal ...

  8. Assessing Internet addiction using the parsimonious Internet addiction components model - a preliminary study [forthcoming


    Kuss, DJ; Shorter, GW; Van Rooij, AJ; Griffiths, MD; Schoenmakers, T.


    Internet usage has grown exponentially over the last decade. Research indicates that excessive Internet use can lead to symptoms associated with addiction. To date, assessment of potential Internet addiction has varied regarding populations studied and instruments used, making reliable prevalence estimations difficult. To overcome the present problems a preliminary study was conducted testing a parsimonious Internet addiction components model based on Griffiths’ addiction components (2005), i...

  9. A Pilot Study on Developing a Standardized and Sensitive School Violence Risk Assessment with Manual Annotation. (United States)

    Barzman, Drew H; Ni, Yizhao; Griffey, Marcus; Patel, Bianca; Warren, Ashaki; Latessa, Edward; Sorter, Michael


    School violence has increased over the past decade and innovative, sensitive, and standardized approaches to assess school violence risk are needed. In our current feasibility study, we initialized a standardized, sensitive, and rapid school violence risk approach with manual annotation. Manual annotation is the process of analyzing a student's transcribed interview to extract relevant information (e.g., key words) to school violence risk levels that are associated with students' behaviors, attitudes, feelings, use of technology (social media and video games), and other activities. In this feasibility study, we first implemented school violence risk assessments to evaluate risk levels by interviewing the student and parent separately at the school or the hospital to complete our novel school safety scales. We completed 25 risk assessments, resulting in 25 transcribed interviews of 12-18 year olds from 15 schools in Ohio and Kentucky. We then analyzed structured professional judgments, language, and patterns associated with school violence risk levels by using manual annotation and statistical methodology. To analyze the student interviews, we initiated the development of an annotation guideline to extract key information that is associated with students' behaviors, attitudes, feelings, use of technology and other activities. Statistical analysis was applied to associate the significant categories with students' risk levels to identify key factors which will help with developing action steps to reduce risk. In a future study, we plan to recruit more subjects in order to fully develop the manual annotation which will result in a more standardized and sensitive approach to school violence assessments.

  10. The ORNL Indoor Air Quality Study: Re-cap, Context, and Assessment on Radon

    Energy Technology Data Exchange (ETDEWEB)

    Tonn, Bruce Edward [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rose, Erin M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ternes, Mark P. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)


    As part of the retrospective evaluation of the U.S. Department of Energy s low-income Weatherization Assistance Program that was led by Oak Ridge National Laboratory (ORNL), an assessment of the impacts of weatherization on indoor air quality (IAQ) was conducted. This assessment included nearly 500 treatment and control homes across the country. Homes were monitored for carbon monoxide, radon, formaldehyde, temperature and humidity pre- and post-weatherization. This report focuses on the topic of radon and addresses issues not thoroughly discussed in the original IAQ report. The size, scope and rigor of the radon component of the IAQ study are compared to previous studies that assessed the impacts of weatherization on indoor radon levels. It is found that the ORNL study is by far the most extensive study conducted to date, though the ORNL results are consistent with the findings of the other studies. However, the study does have limitations related to its reliance on short-term measurements of radon and inability to attribute changes in radon levels in homes post-weatherization to specific weatherization measures individually or in combination.

  11. Mesocosm soil ecological risk assessment tool for GMO 2nd tier studies

    DEFF Research Database (Denmark)

    D'Annibale, Alessandra; Maraldo, Kristine; Larsen, Thomas

    Ecological Risk Assessment (ERA) of GMO is basically identical to ERA of chemical substances, when it comes to assessing specific effects of the GMO plant material on the soil ecosystem. The tiered approach always includes the option of studying more complex but still realistic ecosystem level...... effects in 2nd tier caged experimental systems, cf. the new GMO ERA guidance: EFSA Journal 2010; 8(11):1879. We propose to perform a trophic structure analysis, TSA, and include the trophic structure as an ecological endpoint to gain more direct insight into the change in interactions between species, i.......e. the food-web structure, instead of relying only on the indirect evidence from population abundances. The approach was applied for effect assessment in the agro-ecosystem where we combined factors of elevated CO2, viz. global climate change, and GMO plant effects. A multi-species (Collembola, Acari...

  12. AHP in Assessing Performance of Diploma Institutes – A Case Study

    Directory of Open Access Journals (Sweden)

    Dr. Sujit Kumar Goshal


    Full Text Available Present paper shows application of Analytical Hierarchy Process (AHP as potential tool in decision making in assessing performance of diploma institutes. Parameters for assessing diploma level institutes are used as example. A hierarchical structure is framed for the parameters and the diploma institutes from where feedback received against the parameters for this study. By applying the AHP, the parameters can be prioritized and a descending order list of diploma institutes can be made in order to identify the best performing institutes. A sensitivity analysis can be performed to check the sensitivity of the final selection (decision to minor changes in the judgement. Step by step approaches for applying AHP will be used by using AHP Calculation Software by CGI (web-based free software. It is hoped that this will encourage the application of the AHP in assessing institutional performance of similar institutions.

  13. Atherosclerotic vessel damage in systemic lupus erythematosus and antiphospholipid syndrome in men

    Directory of Open Access Journals (Sweden)

    A. I. Iljina


    Full Text Available Objective. To study prevalence of clinical and subclinical atherosclerosis signs in men with systemic lupus erythematosus (SLE and antiphospholipid syndrome, to assess relationship between atherosclerotic vessel damage, risk factors, CRP and anti-cardiolipin antibodies (АСА Material and methods. 62 pts were included. Mean age was 35,7+11,6 years, mean disease duration - 129,3± 102 months. Traditional and related to the disease risk factors were analyzed. To reveal atherosclerotic vessel damage carotid sonographic examination was performed. Serum CRP concentration was evaluated by high sensitivity nephelometric immunoassay. IgG and IgM АСА were assessed by solid-phase immuno-enzyme assay. Results. Sonographic signs of carotid damage was revealed in 58% of pts, clinical signs of atherosclerosis - in 42%. Pts were divided into two groups according to intima-media complex thickness (IMCT. Group I included 36 pts with atherosclerotic vessel damage signs (IMCT?0,9 mm. Group 2-26 pts with IMCT<0,9 mm. Mean age at the examination, age of disease onset, disease duration, smoking frequency damage index in group I pts were higher than in group 2 pts. Mean CRP concentration in atherosclerosis group was significantly higher than in group 2 (p=0,007. 19 pts had APS signs. 43 pts did not. CRP level significantly correlated with IMCT in SLE pts with and without APS (p<0,05. Pts with atherosclerosis had higher IgG АСА level though the differences were not statistically significant. Conclusion. Men with SLE with or without APS have high risk of atherosclerosis development. CRP elevation is associated with IMCT increase.

  14. Stability and Repeatability of the Distress Thermometer (DT and the Edmonton Symptom Assessment System-Revised (ESAS-r with Parents of Childhood Cancer Survivors.

    Directory of Open Access Journals (Sweden)

    Tatsiana Leclair

    Full Text Available Parents report psychological distress in association with their child's cancer. Reliable tools are needed to screen parental distress over the cancer trajectory. This study aimed to estimate the stability and repeatability of the Distress Thermometer (DT and the Depression and Anxiety items of the Edmonton Symptom Assessment System-revised (ESAS-r-D; -A in parents of children diagnosed with cancer.Fifty parents (28 mothers, median age = 44 of clinically stable survivors of childhood solid and brain tumours completed questionnaires about their own distress (DT, ESAS-r-D; -A, Brief Symptom Inventory-18: BSI-18, Patient Health Questionnaire-9: PHQ-9, Generalized Anxiety Disorder-7: GAD-7 and their children's quality of life (QoL; Peds Quality of Life: PedsQL twice, with a month interval between the two assessments. At retest, parents also evaluated life events that occurred between the two time points. Hierarchical regressions explored moderators for the temporal stability of test measures.Stability estimates were ICC = .78 for the DT, .55 for the ESAS-r-D, and .47 for the ESAS-r-A. Caseness agreement between test and retest was substantial for the DT, fair for the ESAS-r-D, and slight for the ESAS-r-A. Repeatability analyses indicated that the error range for the DT was more than 2 pts below/above actual measurement, whereas it was more than 3 pts for the ESAS-r-A, and 2.5 for the ESAS-r-D. Instability of the DT could be explained by changes in children's physical QoL, but not by other components of QoL or life events. No moderators of stability could be identified for the ESAS-r items.The DT appears to be a fairly stable measure when the respondent's condition is stable yet with a relatively wide error range. Fluctuations in distress-related constructs may affect the temporal stability of the DT. The lower stability of ESAS-r items may result from shorter time-lapse instructions resulting in a greater sensitivity to change. Findings support

  15. Flood Disaster Risk Assessment of Rural Housings — A Case Study of Kouqian Town in China

    Directory of Open Access Journals (Sweden)

    Qi Zhang


    Full Text Available Floods are a devastating kind of natural disaster. About half of the population in China lives in rural areas. Therefore, it is necessary to assess the flood disaster risk of rural housings. The results are valuable for guiding the rescue and relief goods layout. In this study, we take the severe flood disaster that happened at Kouqian Town in Jilin, China in 2010 as an example to build an risk assessment system for flood disaster on rural housings. Based on the theory of natural disaster risk formation and “3S” technology (remote sensing, geography information systems and global positioning systems, taking the rural housing as the bearing body, we assess the flood disaster risk from three aspects: hazard, exposure and vulnerability. The hazard presented as the flood submerging range and depth. The exposure presented as the values of the housing and the property in it. The vulnerability presented as the relationship between the losses caused by flood and flood depth. We validate the model by the field survey after the flood disaster. The risk assessment results highly coincide with the field survey losses. This model can be used to assess the risk of other flood events in this area.

  16. Objective assessment of visual pursuit in patients with disorders of consciousness: an exploratory study. (United States)

    Wannez, Sarah; Hoyoux, Thomas; Langohr, Thomas; Bodart, Olivier; Martial, Charlotte; Wertz, Jérôme; Chatelle, Camille; Verly, Jacques G; Laureys, Steven


    Visual pursuit is a key marker of residual consciousness in patients with disorders of consciousness (DOC). Currently, its assessment relies on subjective clinical decisions. In this study, we explore the variability of such clinical assessments, and present an easy-to-use device composed of cameras and video processing algorithms that could help the clinician to improve the detection of visual pursuit in a clinical context. Visual pursuit was assessed by an experienced research neuropsychologist on 31 patients with DOC and on 23 healthy subjects, while the device was used to simultaneously record videos of both one eye and the mirror. These videos were then scored by three researchers: the experienced research neuropsychologist who did the clinical assessment, another experienced research neuropsychologist, and a neurologist. For each video, a consensus was decided between the three persons, and used as the gold standard of the presence or absence of visual pursuit. Almost 10% of the patients were misclassified at the bedside according to their consensus. An automatic classifier analyzed eye and mirror trajectories, and was able to identify patients and healthy subjects with visual pursuit, in total agreement with the consensus on video. In conclusion, our device can be used easily in patients with DOC while respecting the current guidelines of visual pursuit assessment. Our results suggest that our material and our classification method can identify patients with visual pursuit, as well as the three researchers based on video recordings can.

  17. Flood disaster risk assessment of rural housings--a case study of Kouqian Town in China. (United States)

    Zhang, Qi; Zhang, Jiquan; Jiang, Liupeng; Liu, Xingpeng; Tong, Zhijun


    Floods are a devastating kind of natural disaster. About half of the population in China lives in rural areas. Therefore, it is necessary to assess the flood disaster risk of rural housings. The results are valuable for guiding the rescue and relief goods layout. In this study, we take the severe flood disaster that happened at Kouqian Town in Jilin, China in 2010 as an example to build an risk assessment system for flood disaster on rural housings. Based on the theory of natural disaster risk formation and "3S" technology (remote sensing, geography information systems and global positioning systems), taking the rural housing as the bearing body, we assess the flood disaster risk from three aspects: hazard, exposure and vulnerability. The hazard presented as the flood submerging range and depth. The exposure presented as the values of the housing and the property in it. The vulnerability presented as the relationship between the losses caused by flood and flood depth. We validate the model by the field survey after the flood disaster. The risk assessment results highly coincide with the field survey losses. This model can be used to assess the risk of other flood events in this area.

  18. Importance of hydrological uncertainty assessment methods in climate change impact studies (United States)

    Honti, M.; Scheidegger, A.; Stamm, C.


    Climate change impact assessments have become more and more popular in hydrology since the middle 1980's with a recent boost after the publication of the IPCC AR4 report. During hundreds of impact studies a quasi-standard methodology emerged, which is mainly shaped by the growing public demand for predicting how water resources management or flood protection should change in the following decades. The "standard" workflow relies on a model cascade from global circulation model (GCM) predictions for selected IPCC scenarios to future catchment hydrology. Uncertainty is present at each level and propagates through the model cascade. There is an emerging consensus between many studies on the relative importance of the different uncertainty sources. The prevailing perception is that GCM uncertainty dominates hydrological impact studies. Our hypothesis was that the relative importance of climatic and hydrologic uncertainty is (among other factors) heavily influenced by the uncertainty assessment method. To test this we carried out a climate change impact assessment and estimated the relative importance of the uncertainty sources. The study was performed on two small catchments in the Swiss Plateau with a lumped conceptual rainfall runoff model. In the climatic part we applied the standard ensemble approach to quantify uncertainty but in hydrology we used formal Bayesian uncertainty assessment with two different likelihood functions. One was a time-series error model that was able to deal with the complicated statistical properties of hydrological model residuals. The second was an approximate likelihood function for the flow quantiles. The results showed that the expected climatic impact on flow quantiles was small compared to prediction uncertainty. The source, structure and composition of uncertainty depended strongly on the uncertainty assessment method. This demonstrated that one could arrive to rather different conclusions about predictive uncertainty for the same

  19. The importance of hydrological uncertainty assessment methods in climate change impact studies (United States)

    Honti, M.; Scheidegger, A.; Stamm, C.


    Climate change impact assessments have become more and more popular in hydrology since the middle 1980s with a recent boost after the publication of the IPCC AR4 report. From hundreds of impact studies a quasi-standard methodology has emerged, to a large extent shaped by the growing public demand for predicting how water resources management or flood protection should change in the coming decades. The "standard" workflow relies on a model cascade from global circulation model (GCM) predictions for selected IPCC scenarios to future catchment hydrology. Uncertainty is present at each level and propagates through the model cascade. There is an emerging consensus between many studies on the relative importance of the different uncertainty sources. The prevailing perception is that GCM uncertainty dominates hydrological impact studies. Our hypothesis was that the relative importance of climatic and hydrologic uncertainty is (among other factors) heavily influenced by the uncertainty assessment method. To test this we carried out a climate change impact assessment and estimated the relative importance of the uncertainty sources. The study was performed on two small catchments in the Swiss Plateau with a lumped conceptual rainfall runoff model. In the climatic part we applied the standard ensemble approach to quantify uncertainty but in hydrology we used formal Bayesian uncertainty assessment with two different likelihood functions. One was a time series error model that was able to deal with the complicated statistical properties of hydrological model residuals. The second was an approximate likelihood function for the flow quantiles. The results showed that the expected climatic impact on flow quantiles was small compared to prediction uncertainty. The choice of uncertainty assessment method actually determined what sources of uncertainty could be identified at all. This demonstrated that one could arrive at rather different conclusions about the causes behind

  20. Development of a social skills assessment screening scale for psychiatric rehabilitation settings: A pilot study

    Directory of Open Access Journals (Sweden)

    Poornima Bhola


    Full Text Available Context: Deficits in social skills may present in a range of psychiatric disorders, particularly in the more serious and persistent conditions, and have an influence on functioning across various domains. Aims: This pilot study aimed at developing a brief measure, for structured evaluation and screening for social skills deficits, which can be easily integrated into routine clinical practice. Settings and Design: The sample consisted of 380 inpatients and their accompanying caregivers, referred to Psychiatric Rehabilitation Services at a tertiary care government psychiatric hospital. Materials and Methods: The evaluation included an Inpatient intake Proforma and the 20-item Social Skills Assessment Screening Scale (SSASS. Disability was assessed using the Indian Disability Evaluation and Assessment Scale (IDEAS for a subset of 94 inpatients. Statistical Analysis Used: The analysis included means and standard deviations, frequency and percentages, Cronbach's alpha to assess internal consistency, t-tests to assess differences in social skills deficits between select subgroups, and correlation between SSASS and IDEAS scores. Results: The results indicated the profile of social skills deficits assessed among the inpatients with varied psychiatric diagnoses. The “psychosis” group exhibited significantly higher deficits than the “mood disorder” group. Results indicated high internal consistency of the SSASS and adequate criterion validity demonstrated by correlations with select IDEAS domains. Modifications were made to the SSASS following the pilot study. Conclusions: The SSASS has potential value as a measure for screening and individualised intervention plans for social skills training in mental health and rehabilitation settings. The implications for future work on the psychometric properties and clinical applications are discussed.