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Sample records for asperger syndrome

  1. Asperger syndrome

    Science.gov (United States)

    Asperger syndrome is often considered a high functioning form of autism. It can lead to difficulty interacting socially, repeat behaviors, and clumsiness. Asperger syndrome is a part of the larger developmental disorder ...

  2. Asperger syndrome

    OpenAIRE

    Woodbury-Smith, Marc R.; Volkmar, Fred R.

    2008-01-01

    Abstract Asperger syndrome (AS) is a chronic neurodevelopmental disorder of social interaction, communication, and a restricted range of behaviors or interests. Although not generally associated with intellectual disability, the severe social disability and, in many cases, associated mental health and other medical problems, result in disability throughout life. The diagnosis is often delayed, sometimes into adulthood, which is unfortunate because there are now a range...

  3. Asperger syndrome: an update

    OpenAIRE

    Klin Ami

    2003-01-01

    This article provides an overview of the history and clinical features of Asperger syndrome, and considers guidelines for clinical assessment and treatment. A review of issues related to external validity is provided, which points out the limitations of current research, and lists several potentially beneficial areas of investigation into the nosologic status of the condition. It concludes with a discussion of the unequivocal need of individuals with severe social disabilities for comprehensi...

  4. Asperger syndrome: an update

    Directory of Open Access Journals (Sweden)

    Klin Ami

    2003-01-01

    Full Text Available This article provides an overview of the history and clinical features of Asperger syndrome, and considers guidelines for clinical assessment and treatment. A review of issues related to external validity is provided, which points out the limitations of current research, and lists several potentially beneficial areas of investigation into the nosologic status of the condition. It concludes with a discussion of the unequivocal need of individuals with severe social disabilities for comprehensive and adequate educational services and other treatments irrespective of the fact that the validity and the utility of this specific diagnostic concept is far from resolved.

  5. Genetics Home Reference: Asperger syndrome

    Science.gov (United States)

    ... This interest may be a traditional hobby or academic discipline, and many people with Asperger syndrome develop advanced abilities in fields such as music, science, mathematics, or computer programming. However, they might ...

  6. Asperger Syndrome in children

    Directory of Open Access Journals (Sweden)

    Ioannis Koutelekos

    2009-02-01

    Full Text Available The Asperger’s Syndrome is reported in the pervasive developmental disorders and was categorized as a separate disorder, initially in the ICD -10 (World Health Organization, 1992 and afterwards in the DSM-IV (American Psychiatric Organization, 1994. The Asperger’s Syndrome is distinguished by a team of symptoms that concern the low output in the social interaction and the communication dexterities, as well as the increased stereotypical behavior in various activities and interests.The aim of this particular article that constitutes a case study is the descriptive approach of the Asperger’s Syndrome, through the study of the child behavior.The methodology that was followed in the present case-study was based on inquiring studies and reviews that were drawn from international data bases that correspond to this particular case study of syndrome Asperger in children.Results: The individuals with Asperger’ s syndrome, as well as the case study, tend to experience really big difficulties in elementary social behaviors, as failure in the development and creation of friendly relations or in the search of entertainment activities with others. Moreover, they face difficulties in the comprehension of non verbal communication (body language and the other’s expressions, the body gestures or even the eye contact.Conclusions: The precocious recognition of Asperger’s syndrome is imperative, with final objective the continuous briefing and sensitization of all health professionals, as well as the wider public, toward this syndrome. The earlier a parent foreruns for the diagnosis, the bigger probabilities they stand for a potential functional re-establishment of the syndrome.

  7. [Environmental factors in Asperger syndrome].

    Science.gov (United States)

    Abe, Takaaki; Kato, Satoshi

    2007-03-01

    This paper reviews what is currently known about the environmental factors in Asperger syndrome that is a neurodevelopmental disorder of genetic origins. Its characteristics tend to occur in families of those with the syndrome. The rate of complications during pregnancy or the neonatal period in the patients with Asperger syndrome was about the same as that in the control group. It is true that their involvement in their outer world could not influence the core social deficits very much. But it might facilitate the appearance of the second symptoms such as dissociation, anxiety, depression, persecutory delusion as well as antisocial behavior including serious criminal acts. PMID:17354554

  8. Parental migration and Asperger's syndrome.

    Science.gov (United States)

    Lehti, Venla; Cheslack-Postava, Keely; Gissler, Mika; Hinkka-Yli-Salomäki, Susanna; Brown, Alan S; Sourander, Andre

    2015-08-01

    Parental immigration has been suggested as a possible risk factor for autism spectrum disorders (ASD), but findings have been inconsistent. Very few studies have focused specifically on Asperger's syndrome. The aim of this study was to examine the association between maternal and paternal immigration and the diagnosis of Asperger's syndrome in offspring. The study was a nested case-control study based on a national birth cohort in Finland. Children born in 1987-2005 and diagnosed with Asperger's syndrome by the year 2007 were identified from the Finnish Hospital Discharge Register (N = 1,783). Four matched controls for each case were selected from the Finnish Medical Birth Register (N = 7,106). Information on maternal and paternal country of birth and mother tongue was collected from the Finnish Central Population Register. The study showed that children whose parents are both immigrants have a significantly lower likelihood of being diagnosed with Asperger's syndrome than those with two Finnish parents [adjusted odds ratio (aOR) 0.2, 95 % confidence interval (CI) 0.1-0.4]. No significant associations were found between having only one immigrant parent and the diagnosis of Asperger's syndrome. A regional analysis showed a significantly decreased likelihood of the diagnosis of Asperger's syndrome in children whose mother (aOR 0.1, 95 % CI 0.01-0.5) or father (aOR 0.2, 95 % CI 0.05-0.5) was born in Sub-Saharan Africa. The findings may help in identifying risk factors for different ASD subtypes. On the other hand, they might reflect service use of immigrant families in Finland. PMID:25381114

  9. Higher Education and Asperger's Syndrome

    Science.gov (United States)

    Hughes, Jennifer Lynn

    2009-01-01

    Asperger's syndrome, first listed in the American Psychiatric Association's manual of mental disorders in 1994, affects two to six of every 1,000 Americans, according to the National Institutes of Health. People who have the disorder often have social difficulties, verbal and nonverbal communication problems, and repetitive and restricted…

  10. PRAGMATIC DEFICITS OF ASPERGER SYNDROME

    OpenAIRE

    Silmy Arizatul Humaira’

    2015-01-01

    Human being is social creature who needs other people to interact with. One of the ways to interact with others is communication with language. However, communication could be a complicated problem for those who were born with developmental disorder called Asperger Syndrome (AS). The communication challenge of Asperger’s is the difficulty using language appropriately for social purposes or known as pragmatic deficits. Many excellent books about autism are published whereas knowledge on pragma...

  11. Understanding Asperger Syndrome: A Professor's Guide [DVD

    Science.gov (United States)

    Organization for Autism Research (NJ3), 2011

    2011-01-01

    College can be a trying time in any individual's life. For adults with Asperger Syndrome this experience can be overwhelming. This title in the new DVD series Asperger Syndrome and Adulthood focuses on educating professors, teaching assistants, and others on what it means to be a college student on the spectrum and how they might best be able to…

  12. Offending Behaviour in Adults with Asperger Syndrome

    Science.gov (United States)

    Allen, David; Evans, Carys; Hider, Andrew; Hawkins, Sarah; Peckett, Helen; Morgan, Hugh

    2008-01-01

    Considerable speculation is evident both within the scientific literature and popular media regarding possible links between Asperger syndrome and offending. A survey methodology that utilised quantitative data collection was employed to investigate the prevalence of offending behaviour amongst adults with Asperger Syndrome in a large geographical…

  13. Anxiety in Asperger's Syndrome: Assessment in Real Time

    Science.gov (United States)

    Hare, Dougal J.; Wood, Christopher; Wastell, Sarah; Skirrow, Paul

    2015-01-01

    Anxiety is a major problem for many people with Asperger's syndrome who may have qualitatively different fears from a non-Asperger's syndrome population. Research has relied on measures developed for non-Asperger's syndrome populations that require reporting past experiences of anxiety, which may confound assessment in people with Asperger's…

  14. Iron Deficiency in Autism and Asperger Syndrome.

    Science.gov (United States)

    Latif, A.; Heinz, P.; Cook, R.

    2002-01-01

    Retrospective analysis of the full blood count and, when available, serum ferritin measurements of 96 children (52 with autism and 44 with Asperger syndrome) found six autistic children had iron deficiency and 12 of the 23 autistic children with serum ferritin measures were iron deficient. Far fewer Asperger children were iron deficient. Results…

  15. Asperger Syndrome in children

    OpenAIRE

    Ioannis Koutelekos; Chrysoula Valamoutopoulou

    2009-01-01

    The Asperger’s Syndrome is reported in the pervasive developmental disorders and was categorized as a separate disorder, initially in the ICD -10 (World Health Organization, 1992) and afterwards in the DSM-IV (American Psychiatric Organization, 1994). The Asperger’s Syndrome is distinguished by a team of symptoms that concern the low output in the social interaction and the communication dexterities, as well as the increased stereotypical behavior in various activities and interests.The aim o...

  16. Stottern/Poltern oder Asperger Syndrom?

    OpenAIRE

    Brunner, M; Lozano, G.; Pröschel, U

    2005-01-01

    Kinder mit Asperger Syndrom (AS) werden häufig zu spät oder fehldiagnostiziert und damit auch fehltherapiert. Die Diagnose eines AS innerhalb der phoniatrischen Ambulanz wird dadurch erschwert, dass die Kernsymptome, die sozialkommunikativen Auffälligkeiten, auch als Folgeerscheinung bei Sprachentwicklungsverzögerung (SEV) und Stottern/Poltern auftreten können. Bezüglich des Kriteriums "gestörte Sprachentwicklung" herrschen in der Literatur zum Asperger Syndrom divergente Auffassungen. Auch w...

  17. Asperger syndrome: an update Síndrome de Asperger

    OpenAIRE

    Ami Klin

    2003-01-01

    This article provides an overview of the history and clinical features of Asperger syndrome, and considers guidelines for clinical assessment and treatment. A review of issues related to external validity is provided, which points out the limitations of current research, and lists several potentially beneficial areas of investigation into the nosologic status of the condition. It concludes with a discussion of the unequivocal need of individuals with severe social disabilities for comprehensi...

  18. Asperger syndrome related suicidal behavior: two case studies

    Directory of Open Access Journals (Sweden)

    Kocourkova J

    2013-11-01

    Full Text Available Jana Kocourkova, Iva Dudova, Jiri Koutek Department of Child Psychiatry, Charles University Second Faculty of Medicine, University Hospital Motol, Prague, Czech Republic Abstract: Asperger syndrome hinders adaptation to developmental challenges during childhood and adolescence, particularly with regard to interpersonal relationships. Individuals with Asperger syndrome display lack of empathy and limited ability to understand social and emotional exchanges with other people. Individuals with Asperger syndrome are significantly exposed to the risk of suicidal behavior, especially during adolescence. The authors describe cases of suicidal behavior in two adolescent boys with Asperger syndrome. Keywords: Asperger syndrome, suicidal behavior, adolescence

  19. Giftedness and Asperger's Syndrome: A New Agenda for Education.

    Science.gov (United States)

    Gallagher, Shelagh A.; Gallagher, James J.

    2002-01-01

    This article describes the characteristics of students with Asperger syndrome and discusses identifying students with Asperger syndrome who are also gifted. Classroom interventions for these twice exceptional students are addressed and the need for intervention that is highly individualized is stressed. Diagnostic criteria for Asperger's disorder…

  20. Adults with Asperger Syndrome: A Childhood Disorder Grows Up

    Science.gov (United States)

    Wilkinson, Lee A.

    2007-01-01

    Asperger syndrome is a chronic developmental disorder characterized by problems in social relatedness, empathic communication and understanding, and circumscribed interests. The inclusion of Asperger's Disorder (Asperger syndrome) in the "Diagnostic and Statistical Manual of Mental Disorders" (DSM-IV; American Psychiatric Association, 1994), has…

  1. PRAGMATIC DEFICITS OF ASPERGER SYNDROME

    Directory of Open Access Journals (Sweden)

    Silmy Arizatul Humaira’

    2015-08-01

    Full Text Available Human being is social creature who needs other people to interact with. One of the ways to interact with others is communication with language. However, communication could be a complicated problem for those who were born with developmental disorder called Asperger Syndrome (AS. The communication challenge of Asperger’s is the difficulty using language appropriately for social purposes or known as pragmatic deficits. Many excellent books about autism are published whereas knowledge on pragmatic deficits are still very limited. Thus, it is expected to be a beneficial reference to understand the pragmatic deficits and to create strategies for them to communicate effectively. Therefore, this study aimed at exploring the kinds of pragmatic deficits of an individual with AS. The verbal language profiles of autism purposed by MacDonald (2004 is used to analyzed the data in depth. The descriptive qualitative method is applied to develop a comprehensive understanding about the AS case in Temple Grandin movie.The finding shows that all of the five types of communication deficits are appearing and the dominant of which is unresponsive.

  2. Sleep in Children with Asperger Syndrome

    Science.gov (United States)

    Paavonen, E. Juulia; Vehkalahti; Kimmo; Vanhala, Raija; von Wendt, Lennart; Nieminen-von Wendt, Taina; Aronen, Eeva T.

    2008-01-01

    The prevalence of sleep disturbances in 52 children with Asperger syndrome (AS) as compared with 61 healthy controls (all subjects aged 5-17 years) was investigated. Problems with sleep onset and maintenance, sleep-related fears, negative attitudes toward sleeping, and daytime somnolence were more frequent among children with AS than among…

  3. Language Abilities of Children with Asperger Syndrome

    Science.gov (United States)

    Saalasti, Satu; Lepisto, Tuulia; Toppila, Esko; Kujala, Teija; Laakso, Minna; Nieminen-von Wendt, Taina; von Wendt, Lennart; Jansson-Verkasalo, Eira

    2008-01-01

    Current diagnostic taxonomies (ICD-10, DSM-IV) emphasize normal acquisition of language in Asperger syndrome (AS). Although many linguistic sub-skills may be fairly normal in AS there are also contradictory findings. There are only few studies examining language skills of children with AS in detail. The aim of this study was to study language…

  4. Facilitating Support for Students with Asperger's Syndrome

    Science.gov (United States)

    Pillay, Yegan; Bhat, Christine Suniti

    2012-01-01

    The number of students with Asperger's Syndrome enrolled at tertiary institutions in the United States continues to increase. This can be attributed to: (a) the passage of legislations such as the Individuals with Disabilities Act (IDEA) and the Americans with Disabilities Act of 1990 (ADA); (b) revisions to the "Diagnostic and Statistical Manual"…

  5. Intervention ABCs for Children with Asperger Syndrome.

    Science.gov (United States)

    Safran, Stephen P.; Safran, Joan S.; Ellis, Kathleen

    2003-01-01

    This article first describes the indicators of Asperger syndrome (AS), followed by an overview of screening and diagnostic procedures. Next, it discusses knowledge-based interventions addressing deficits in academics, behavior, and communication. Implications for speech language pathologists and related professionals working with students with…

  6. Review of the Asperger Syndrome Diagnostic Scale.

    Science.gov (United States)

    Goldstein, Sam

    2002-01-01

    The reliability, validity, and clinical utility of the Asperger Syndrome Diagnostic Scale in the diagnosis of pervasive developmental disorders are reviewed. While the measure holds promise as a research tool, there appears little evidence that it can distinguish among the variety of types of pervasive developmental disorders, or diagnose Asperger…

  7. Comparison of Diagnostic Methods for Asperger Syndrome

    Science.gov (United States)

    Kopra, Kristiina; von Wendt, Lennart; Nieminen-von Wendt, Taina; Paavonen, E. Julia

    2008-01-01

    Several different diagnostic sets of criteria exist for Asperger syndrome (AS), but there is no agreement on a gold standard. The aim of this study was to compare four diagnostic sets of criteria for AS: the ICD-10, the DSM-IV, the Gillberg & Gillberg, and the Szatmari criteria. The series consists of 36 children who had been referred to two…

  8. Did Mozart suffer from Asperger syndrome?

    Science.gov (United States)

    Raja, Michele

    2015-05-01

    The most reliable biographies of Mozart highlight elements that are compatible with current diagnostic criteria for Asperger syndrome including qualitative impairment in social interaction and stereotyped and repetitive motor mannerisms. Furthermore, numerous features are documented including difficulty in communicating his emotional state and in inferring the mental state of his interlocutors, motor clumsiness, specific skills and genius, left-handedness, special sense of humour, physical developmental abnormalities, bizarre thinking, overvalued ideas and delusions. PMID:24585598

  9. Comorbidity of Asperger's syndrome and Bipolar disorder

    OpenAIRE

    Azzoni Antonella; Raja Michele

    2008-01-01

    Abstract Background and objective Asperger's Syndrome (AS) is a pervasive developmental disorder that is sometimes unrecognized, especially in the adult psychiatric setting. On the other hand, in patients with an AS diagnosis, comorbid psychiatric disorders may be unrecognized in the juvenile setting. The aim of the paper is to show and discuss some troublesome and complex problems of the management of patients with AS and comorbid Bipolar Disorder (BD). Methods The paper describes three pati...

  10. Presentation of Depression in Autism and Asperger Syndrome: A Review

    Science.gov (United States)

    Stewart, Mary E.; Barnard, Louise; Pearson, Joanne; Hasan, Reem; O'Brien, Gregory

    2006-01-01

    Depression is common in autism and Asperger syndrome, but despite this, there has been little research into this issue. This review considers the current literature on the prevalence, presentation, treatment and assessment of depression in autism and Asperger syndrome. There are diagnostic difficulties when considering depression in autism and…

  11. Theory of Mind in Adults with HFA and Asperger Syndrome

    Science.gov (United States)

    Spek, Annelies A.; Scholte, Evert M.; Van Berckelaer-Onnes, Ina A.

    2010-01-01

    Theory of mind was assessed in 32 adults with HFA, 29 adults with Asperger syndrome and 32 neurotypical adults. The HFA and Asperger syndrome groups were impaired in performance of the Strange stories test and the Faux-pas test and reported more theory of mind problems than the neurotypical adults. The three groups did not differ in performance of…

  12. Asperger's Syndrome, Subjectivity and the Senses.

    Science.gov (United States)

    Badone, Ellen; Nicholas, David; Roberts, Wendy; Kien, Peter

    2016-09-01

    Situated at the intersection of anthropological work on illness narratives and research on the anthropology of autism, this paper is a close reading of an autobiographical narrative recounted by Peter, a young man diagnosed with Asperger's Syndrome, a type of autism spectrum disorder (ASD). Responding to Solomon's (2010a:252) call for phenomenologically grounded accounts of "the subjective, sensory, and perceptual experiences of autism … based on personal narratives and practices of being and self-awareness," this paper calls into question key assumptions in the clinical and popular literature about ASD relating to theory of mind, empathy, capacity for metaphorical thinking, and ASD as a life-long condition. PMID:26838589

  13. Insomnia is a frequent finding in adults with Asperger syndrome

    OpenAIRE

    von Wendt Lennart; Nieminen-von Wendt Taina; Lindberg Nina; Tani Pekka; Alanko Lauri; Appelberg Björn; Porkka-Heiskanen Tarja

    2003-01-01

    Abstract Background Asperger syndrome (AS) is a neurodevelopmental disorder belonging to autism spectrum disorders with prevalence rate of 0,35% in school-age children. It has been most extensively studied in childhood while there is scarcity of reports concerning adulthood of AS subjects despite the lifelong nature of this syndrome. In children with Asperger syndrome the initiation and continuity of sleep is disturbed because of the neuropsychiatric deficits inherent of AS. It is probable th...

  14. Early-onset anorexia nervosa in girls with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Dudova I

    2015-07-01

    Full Text Available Iva Dudova, Jana Kocourkova, Jiri Koutek Department of Child Psychiatry, Charles University Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic Abstract: Eating disorders frequently occur in conjunction with autism spectrum disorders, posing diagnostic and therapeutic difficulties. The comorbidity of anorexia nervosa and Asperger syndrome is a significant clinical complication and has been associated with a poorer prognosis. The authors are presenting the cases of an eleven-year-old girl and a five-and-a-half-year-old girl with comorbid eating disorders and Asperger syndrome. Keywords: eating disorders, early-onset anorexia nervosa, autism spectrum disorders, Asperger syndrome, diagnostics, therapy

  15. Asperger's syndrome: diagnosis, comorbidity and therapy.

    Science.gov (United States)

    Tarazi, F I; Sahli, Z T; Pleskow, J; Mousa, S A

    2015-03-01

    Asperger's syndrome (AS), a behavioral disorder that is related to autism, is associated with abnormal social functioning and repetitive behaviors but not with a decrease in intelligence or linguistic functionality. This article reviews the clinical diagnosis of AS and discusses the comorbid disorders that may be present with AS, as well as the efficacy, safety, and tolerability of pharmacotherapies given to AS patients, as reported in preclinical and clinical studies. AS may be present with several comorbid disorders including: attention deficit hyperactivity disorder, anxiety, schizophrenia, bipolar disorder, depression, and Tourette's syndrome. The difficulty in distinguishing AS from autism results in treating the comorbid disorder symptoms, rather than treating the symptoms of AS. Accordingly, there is a great need to further understand the psychobiology of AS and its association with other disorders, which should expand the pharmacological and non-pharmacological therapeutic options and improve the quality of life for AS patients. PMID:25655905

  16. Early-onset anorexia nervosa in girls with Asperger syndrome.

    Science.gov (United States)

    Dudova, Iva; Kocourkova, Jana; Koutek, Jiri

    2015-01-01

    Eating disorders frequently occur in conjunction with autism spectrum disorders, posing diagnostic and therapeutic difficulties. The comorbidity of anorexia nervosa and Asperger syndrome is a significant clinical complication and has been associated with a poorer prognosis. The authors are presenting the cases of an eleven-year-old girl and a five-and-a-half-year-old girl with comorbid eating disorders and Asperger syndrome. PMID:26170676

  17. Differensialdiagnostiske avveininger ved Asperger syndrom, ADHD og Reaktiv tilknytningsforstyrrelse

    OpenAIRE

    Høidal, Reidun

    2013-01-01

    Problemstilling: Det er en todelt problemstilling i denne oppgaven:«Årsaker til, symptomer ved og barne- og ungdomspsykiatrisk utredning av Asperger syndrom, ADHD og RAD» «Overlappende symptomer og differnesialdiagnostiske kriterier for å skille mellom Asperger syndrom, ADHD og RAD»Metode: Litteratursøk i Google Scholar-basen gjennomført 17,18 og 19.januar 2012. Søkeordene var: ADHD/hyperkinetisk forstyrrelse, reactive attachment disorders, disinhibibited attachment, inhibited attachment, att...

  18. Comorbidity of Asperger's syndrome and Bipolar disorder

    Directory of Open Access Journals (Sweden)

    Azzoni Antonella

    2008-11-01

    Full Text Available Abstract Background and objective Asperger's Syndrome (AS is a pervasive developmental disorder that is sometimes unrecognized, especially in the adult psychiatric setting. On the other hand, in patients with an AS diagnosis, comorbid psychiatric disorders may be unrecognized in the juvenile setting. The aim of the paper is to show and discuss some troublesome and complex problems of the management of patients with AS and comorbid Bipolar Disorder (BD. Methods The paper describes three patients affected by AS and bipolar spectrum disorders. Results and conclusion Mood stabilizers and 2nd generation antipsychotics were effective in the treatment of these AS patients with comorbid BD, while the use of antidepressants was associated with worsening of the mood disorder. It is of importance to recognize both the psychiatric diagnoses in order to arrange an exhaustive therapeutic program and to define specific and realistic goals of treatment.

  19. Aspergers--different, not less: occupational strengths and job interests of individuals with Asperger's Syndrome.

    Directory of Open Access Journals (Sweden)

    Timo Lorenz

    Full Text Available Rooted in the neurodiversity approach, this study provides an overview of the strengths and interests of individuals with Asperger's Syndrome. We interviewed 136 individuals with Asperger's Syndrome and 155 neurotypical individuals via an online survey with regards to (a demography, (b occupational strengths, (c general self-efficacy, (d occupational self-efficacy, and (e the job interest profile according to Holland. The vocational and educational fields of the individuals with Asperger's in the sample are more diverse than and surpass those classical fields stated in research and biographical literature. The comparison of both groups in cross-tables showed that the indicated strengths differ in several areas (ΦCramer = .02-.47, which means that a specific strength profile can be derived, and this profile goes beyond the clinical view of the diagnostic criteria. Individuals with Asperger's indicate lower self-efficacy, both general and occupational. Furthermore, a high concentration of individuals with Asperger's can be found in the areas I (Investigative and C (Conventional of Holland's RIASEC model.

  20. Neurofeedback outcomes in clients with Asperger's syndrome.

    Science.gov (United States)

    Thompson, Lynda; Thompson, Michael; Reid, Andrea

    2010-03-01

    This paper summarizes data from a review of neurofeedback (NFB) training with 150 clients with Asperger's Syndrome (AS) and 9 clients with Autistic Spectrum Disorder (ASD) seen over a 15 year period (1993-2008) in a clinical setting. The main objective was to investigate whether electroncephalographic (EEG) biofeedback, also called neurofeedback (NFB), made a significant difference in clients diagnosed with AS. An earlier paper (Thompson et al. 2009) reviews the symptoms of AS, highlights research findings and theories concerning this disorder, discusses QEEG patterns in AS (both single and 19-channel), and details a hypothesis, based on functional neuroanatomy, concerning how NFB, often paired with biofeedback (BFB), might produce a change in symptoms. A further aim of the current report is to provide practitioners with a detailed description of the method used to address some of the key symptoms of AS in order to encourage further research and clinical work to refine the use of NFB plus BFB in the treatment of AS. All charts were included for review where there was a diagnosis of AS or ASD and pre- and post-training testing results were available for one or more of the standardized tests used. Clients received 40-60 sessions of NFB, which was combined with training in metacognitive strategies and, for most older adolescent and adult clients, with BFB of respiration, electrodermal response, and, more recently, heart rate variability. For the majority of clients, feedback was contingent on decreasing slow wave activity (usually 3-7 Hz), decreasing beta spindling if it was present (usually between 23 and 35 Hz), and increasing fast wave activity termed sensorimotor rhythm (SMR) (12-15 or 13-15 Hz depending on assessment findings). The most common initial montage was referential placement at the vertex (CZ) for children and at FCz (midway between FZ and CZ) for adults, referenced to the right ear. Metacognitive strategies relevant to social understanding, spatial

  1. Exploratory Study of Childbearing Experiences of Women With Asperger Syndrome.

    Science.gov (United States)

    Gardner, Marcia; Suplee, Patricia D; Bloch, Joan; Lecks, Karen

    2016-01-01

    Increasing numbers of girls have been diagnosed with Asperger syndrome and other autism spectrum disorders (ASDs) over the past two decades; therefore, more women with ASDs are entering the childbearing phase of their lives. Little is known about the childbearing experiences of women with ASDs. This qualitative study describes the childbearing experiences of eight women with Asperger syndrome. Four major themes emerged: Processing Sensations, Needing to Have Control, Walking in the Dark, and Motherhood on My Own Terms. Clinicians can provide sensitive, individualized care by asking women with Asperger syndrome about their specific sensory experiences, counseling them about coping strategies for sensory intrusions, providing targeted support, and modifying the clinical environment to decrease distressing stimuli. PMID:26902438

  2. NEUROBILOGY OF ASPERGER'S SYNDROME : A CASE STUDY AND OVERVIEW

    OpenAIRE

    Duggal, Harpreet S.; Dutta, Siddhartha; Sinha, Vinod K.; Basu, Soumya; Pandey, Smita; Nizamie, Haque S.; Nizamie, Alka

    2001-01-01

    Asperger's syndrome is an autistic spectrum disorder, which has engendered lesser attention in comparison to autism. Recent literature has focused on the involvement of cortical areas of the brain in this syndrome. We report a case of Asperger′s syndrome in which an extensive work-up, including neuropsychological, neurophysiological and neuroimaging procedures, were undertaken. The findings of the various investigative procedures are discussed and literature supporting the neurobiological bas...

  3. Getting to Know the Child with Asperger Syndrome

    Science.gov (United States)

    Gibbons, Melinda M.; Goins, Shelley

    2008-01-01

    Asperger syndrome (AS) is a disorder characterized by social skill deficits and display of repetitive behaviors. This article explores the diagnostic components of AS and describes the major school-related issues for children who have the disorder. Specific interventions that school counselors can implement to help increase these students'…

  4. Brief Report: Asperger's Syndrome and Sibling Birth Order

    Science.gov (United States)

    Schmidt, Karmen; Zimmerman, Andrew; Bauman, Margaret; Ferrone, Christine; Venter, Jacob; Spybrook, Jessaca; Henry, Charles

    2013-01-01

    Prior investigations suggest that birth order position may be associated with the risk for developing a pervasive developmental disorder. This retrospective chart review examined the birth order status of 29 psychiatrically-referred patients with Asperger's Syndrome (AS). Eighty-six percent of the subjects were first born. The finding was…

  5. Brief Report: Should the DSM V Drop Asperger Syndrome?

    Science.gov (United States)

    Ghaziuddin, Mohammad

    2010-01-01

    The DSM IV defines Asperger syndrome (AS) as a pervasive developmental (autistic spectrum) disorder characterized by social deficits and rigid focused interests in the absence of language impairment and cognitive delay. Since its inclusion in the DSM-IV, there has been a dramatic increase in its recognition both in children and adults. However,…

  6. Supporting Students with Asperger Syndrome on College Campuses: Current Practices

    Science.gov (United States)

    Barnhill, Gena P.

    2016-01-01

    With the increasing number of students with Asperger syndrome (AS) and high functioning autism (HFA) enrolling in college, it has become apparent that support services are greatly needed to assist these students in navigating college life, both academically and socially. Yet, there is a dearth of research describing the specific supports needed…

  7. Linguistic Alignment in Adults with and without Asperger's Syndrome

    Science.gov (United States)

    Slocombe, Katie E.; Alvarez, Ivan; Branigan, Holly P.; Jellema, Tjeerd; Burnett, Hollie G.; Fischer, Anja; Li, Yan Hei; Garrod, Simon; Levita, Liat

    2013-01-01

    Individuals with Asperger's Syndrome (AS) often have difficulties with social interactions and conversations. We investigated if these difficulties could be attributable to a deficit in the ability to linguistically converge with an interlocutor, which is posited to be important for successful communication. To that end, participants completed two…

  8. Timing Deficits Are Implicated in Motor Dysfunction in Asperger's Syndrome

    Science.gov (United States)

    Price, Kelly J.; Edgell, Dorothy; Kerns, Kimberly A.

    2012-01-01

    This study addressed what role movement timing irregularities have in producing the motor deficits documented in Asperger's Syndrome (AS). Participants included males with AS (n = 14) and without (n = 16), matched by age (7-23 years) and with no significant IQ differences. They completed measures of timing perception (comparisons of tempo of…

  9. Exploring Fathers' Perceptions of Parenting a Child with Asperger Syndrome

    Science.gov (United States)

    O' Halloran, Maeve; Sweeney, John; Doody, Owen

    2013-01-01

    This study explores Irish fathers' perceptions of parenting a child with Asperger syndrome (AS). Ethical approval was granted by the service provider, and Husserlian phenomenological approach facilitated the exploration. Data were collected through semi-structured interviews of nine fathers in the West region of Ireland. Data were transcribed and…

  10. School-Based Practices for Asperger Syndrome: A Canadian Perspective

    Science.gov (United States)

    McCrimmon, Adam W.; Altomare, Alyssa A.; Matchullis, Ryan L.; Jitlina, Katia

    2012-01-01

    Educators face increasing demands to provide quality education in their classrooms, particularly to students with exceptional needs. Students with Asperger syndrome (AS) represent a population experiencing significant nonacademic barriers to learning (e.g., social, emotional, and behavioural needs). However, educational policies that identify and…

  11. Epilepsy in Individuals with a History of Asperger's Syndrome

    DEFF Research Database (Denmark)

    Rich, Bente; Isager, Torben; Mouridsen, Svend Erik Birkebæk

    2013-01-01

    We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger's syndrome on February 7, 2011. All 4,180 identified cases with AS (3...

  12. Physical Education and Implications for Students with Asperger's Syndrome

    Science.gov (United States)

    Simpson, Cynthia G.; Gaus, Mark D.; Biggs, Mary Jo Garcia; Williams, James, Jr.

    2010-01-01

    In this article, James Williams, a young man with Asperger's syndrome (AS) shares his experiences taking physical education in a generalized education setting and discusses the implications for students with AS. He was diagnosed with AS when he was 9 years old. School was tough at times, especially when social interactions came into play. One of…

  13. Asperger Syndrome and Schizophrenia: A Comparative Neuropsychological Study

    Science.gov (United States)

    Marinopoulou, Maria; Lugnegård, Tove; Unenge Hallerbäck, Maria; Gillberg, Christopher; Billstedt, Eva

    2016-01-01

    There has been an increasing interest in possible connections between autism spectrum disorder (ASD) and schizophrenia in the last decade. Neuropsychological comparison studies have, however, been few. The present study examined similarities and differences in intellectual and executive functioning between adults with Asperger syndrome (AS) and…

  14. Atypical Prosody in Asperger Syndrome: Perceptual and Acoustic Measurements

    Science.gov (United States)

    Filipe, Marisa G.; Frota, Sónia; Castro, São Luís; Vicente, Selene G.

    2014-01-01

    It is known that individuals with Asperger syndrome (AS) may show no problems with regard to what is said (e.g., lexical content) but tend to have difficulties in how utterances are produced, i.e., they may show prosodic impairments. In the present study, we focus on the use of prosodic features to express grammatical meaning. Specifically, we…

  15. Head Circumference in Autism, Asperger Syndrome and ADHD

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2002-06-01

    Full Text Available Occipitofrontal circumference (OFC, measured at birth and after 16 months of age, was compared in 50 consecutive patients with Asperger syndrome, 50 diagnosed with autistic disorder, and 50 with ADHD and followed at the Department of Child and Adolescent Psychiatry, Goteborg University, Sweden.

  16. Head Circumference in Autism, Asperger Syndrome and ADHD

    OpenAIRE

    J Gordon Millichap

    2002-01-01

    Occipitofrontal circumference (OFC), measured at birth and after 16 months of age, was compared in 50 consecutive patients with Asperger syndrome, 50 diagnosed with autistic disorder, and 50 with ADHD and followed at the Department of Child and Adolescent Psychiatry, Goteborg University, Sweden.

  17. Social Vulnerability and Bullying in Children with Asperger Syndrome

    Science.gov (United States)

    Sofronoff, Kate; Dark, Elizabeth; Stone, Valerie

    2011-01-01

    Children with Asperger syndrome (AS) have IQ within the normal range but specific impairments in theory of mind, social interaction and communication skills. The majority receive education in mainstream schools and research suggests they are bullied more than typically developing peers. The current study aimed to evaluate factors that predict…

  18. Cell Phone Use by Adolescents with Asperger Syndrome

    Science.gov (United States)

    Durkin, Kevin; Whitehouse, Andrew; Jaquet, Emma; Ziatas, Kathy; Walker, Allan J.

    2010-01-01

    While young people have generally been at the forefront of the adoption and use of new communications technologies, little is known of uses by exceptional youth. This study compares cell phone use by a group of adolescents with Asperger Syndrome (n = 35) with that by a group of adolescents with typical development (n = 35). People with Asperger…

  19. Social difficulties in children with Asperger syndrome : how to prevent social deficiencies and enhance social skills

    OpenAIRE

    2007-01-01

    Asperger syndrome has received increasing attention during the last decade. Even though individual differences exist, it is generally recognized that children with Asperger syndrome have extensive social deficiencies. Social difficulties are key factors for diagnosing this disorder. The aims of this study were to discuss social difficulties in children with Asperger syndrome and examine effective strategies to prevent social deficiencies and enhance social abilities. Based on this researc...

  20. Self-Perceptions of a High School Female Adolescent with Asperger Syndrome: A Case History

    Science.gov (United States)

    Edwards, Kemberly V.

    2012-01-01

    The purpose of this study is to increase the knowledge base about female adolescents with Asperger syndrome (AS). The findings will be useful in providing educators with an insight into the social world of Asperger syndrome in order to give them a better understanding of the syndrome, and to assist them in teaching students more effectively. The…

  1. [Asperger's syndrome in family context--review of studies].

    Science.gov (United States)

    Zmijewska, Anna

    2010-01-01

    In recent years in the face of still growing number of diagnosis of pervasive developmental disorders there has been an increase in number of research in the functioning of family of children with autism or Asperger's Syndrome. Studies concerning families of children with autism have been predominantly occupied with the stress-coping strategies and also with the therapeutic effect of interaction between disabled children and the rest of the family. New studies with families of children with Asperger's Syndrome, apart from the coping styles of parents and the received support, are also examining the properties of the system of these families, like: cohesion, adaptability, organisation, control, expressiveness or conflict. Such a perspective enables researchers to describe the circularity of influences in these families, on the other hand, however, some methodological deficiencies of this research, as well as the lack of longitudinal studies prevent researchers from creating a comprehensive picture of functioning of these families. PMID:21452506

  2. DID FIELD MARSHAL BERNARD MONTGOMERY (MONTGOMERY OF ALAMEIN) HAVE ASPERGER'S SYNDROME?

    OpenAIRE

    Fitzgerald, Michael

    2000-01-01

    In the present paper the evidence for Field Marshal Montgomery having Asperger's syndrome is examined. Biographies of Montgomery were examined to search for evidence that he met criteria for Asperger's syndrome - Gillberg (1991) and Asperger's disorder (APA.1994) and Anankastic personality disorder (WHO,1992). He demonstrates a qualitative impairment in social interaction and restricted repetitive and stereotyped patterns of behaviour, interests and activities. It can be concluded that he met...

  3. Early-onset anorexia nervosa in girls with Asperger syndrome

    OpenAIRE

    Dudova I; Kocourkova J; Koutek J

    2015-01-01

    Iva Dudova, Jana Kocourkova, Jiri Koutek Department of Child Psychiatry, Charles University Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic Abstract: Eating disorders frequently occur in conjunction with autism spectrum disorders, posing diagnostic and therapeutic difficulties. The comorbidity of anorexia nervosa and Asperger syndrome is a significant clinical complication and has been associated with a poorer prognosis. The authors are presenting the cases ...

  4. The Relationship between Subclinical Asperger's Syndrome and Frontotemporal Lobar Degeneration

    OpenAIRE

    Midorikawa, Akira; Kawamura, Mitsuru

    2012-01-01

    Background/Aims The existence of the behavioral variant of frontotemporal dementia (bv-FTD), including senile Asperger's syndrome (AS), has been proposed. However, there are no empirical case reports to support the proposal. In this report, we present 3 patients who showed symptoms of bv-FTD and demonstrated signs of autistic spectrum disorder, especially AS. Methods We evaluated 3 subjects using the diagnostic criteria for bv-FTD, and their caregivers retrospectively provided data to calcula...

  5. Mentalising and social problem solving in adults with Asperger's syndrome

    OpenAIRE

    Channon, S; Crawford, S; Orlowska, D.; Parikh, N.; Thoma, P.

    2013-01-01

    It is well established that autistic spectrum disorder is linked to difficulties with mentalising, but the ways in which this affects everyday behaviour is less well understood. This study explored the nature and extent of difficulties in everyday social functioning in adults with Asperger's syndrome (AS), since increased understanding can enhance the development of more effective intervention strategies. Methods Individuals with AS (n=21) were compared with healthy control participants (n=21...

  6. The "Not Guilty Verdict": Psychological Reactions to a Diagnosis of Asperger Syndrome in Adulthood

    Science.gov (United States)

    Punshon, C.; Skirrow, P.; Murphy, G.

    2009-01-01

    Asperger syndrome is a relatively new diagnostic classification. A number of factors make receiving a diagnosis of Asperger syndrome in adulthood a unique experience. This study used a phenomenological approach to examine the experiences of 10 adults receiving such a diagnosis. Results suggested that six major themes were associated with receiving…

  7. Adolescents with Asperger Syndrome Can Use a Mindfulness-Based Strategy to Control Their Aggressive Behavior

    Science.gov (United States)

    Singh, Nirbhay N.; Lancioni, Giulio E.; Singh, Angela D. A.; Winton, Alan S. W.; Singh, Ashvind N. A.; Singh, Judy

    2011-01-01

    Children and adolescents with Asperger syndrome occasionally exhibit aggressive behavior against peers and parents. In a multiple baseline design across subjects, three adolescents with Asperger syndrome were taught to use a mindfulness-based procedure called "Meditation on the Soles of the Feet" to control their physical aggression in the family…

  8. Strategies to Increase the Physical Activity Participation of Young Adults with Asperger Syndrome in Community Programs

    Science.gov (United States)

    Hamm, Jessica; Driver, Simon

    2015-01-01

    Currently one in 50 American school-age children is diagnosed with Autism. Although Asperger Syndrome is no longer acknowledged as a separate diagnosis, this article refers to high-functioning individuals with Autism as having Asperger Syndrome, since it is a culturally relevant term. One of the most challenging times for individuals with Asperger…

  9. Social Skills Training for Adolescents with Asperger's Syndrome Using a Consultation Model

    Science.gov (United States)

    Minihan, Aileen; Kinsella, William; Honan, Rita

    2011-01-01

    A case study design was used to evaluate the effectiveness of behavioural consultation as a method for improving the social skills of adolescents with Asperger's syndrome. Two case studies were conducted. In each study, two teachers implemented a social skills programme with two to three adolescents with Asperger's syndrome in a group setting with…

  10. Comparison of Pausing Behavior in Children Who Stutter and Children Who Have Asperger Syndrome

    Science.gov (United States)

    Beltrame, Jessica Monique; Viera, Renata Alves Torello; Tamanaha, Ana Carina; Arcuri, Claudia Fassin; Osborn, Ellen; Perissinoto, Jacy; Schiefer, Ana Maria

    2011-01-01

    Purpose: The objective of this research was to compare the number and types of grammatical and non-grammatical silent pauses presented by stutterers and subjects with Asperger syndrome in their narratives. Method: Ten children who stutter and four participants with Asperger syndrome (mean ages of both groups 10 years) were assessed at the Speech…

  11. Referral Pattern and Special Interests in Children and Adolescents with Asperger Syndrome: A Turkish Referred Sample

    Science.gov (United States)

    Tanidir, Canan; Mukaddes, Nahit M.

    2014-01-01

    Objectives: To investigate the most frequent reasons for referral, the most common special interests, age at first referral to a mental health service, and the age of diagnosis in children and adolescents with Asperger syndrome living in Turkey. Methods: This study includes 61 children and adolescents diagnosed with Asperger syndrome using…

  12. The Use of WAIS-III in Adults with HFA and Asperger Syndrome

    Science.gov (United States)

    Spek, Antoinette A.; Scholte, Evert M.; van Berckelaer-Onnes, Ina A.

    2008-01-01

    The WAIS III was administered to 16 adults with high functioning autism (HFA) and 27 adults with Asperger syndrome. Differences between Verbal Intelligence (VIQ) and Performance Intelligence (PIQ) were not found. Processing Speed problems in people with HFA appeared. At the subtest level, the Asperger syndrome group performed weak on Digit Span.…

  13. "We Are All There Silently Coping." The Hidden Experiences of Parents of Adults with Asperger Syndrome

    Science.gov (United States)

    Griffith, Gemma M.; Totsika, Vasiliki; Nash, Susie; Jones, Robert S. P.; Hastings, Richard P.

    2012-01-01

    Background: The experiences of older parents of adults with Asperger syndrome have not been explored in the research literature. Method: Four families who had middle-aged offspring with Asperger syndrome were interviewed (3 mothers and 1 couple), and the interviews were analysed using interpretative phenomenological analysis (IPA). Results: Six…

  14. The Efficacy of Social Skills Treatment for Children with Asperger Syndrome

    Science.gov (United States)

    Elder, Lisa M.; Caterino, Linda C.; Chao, Janet; Shaknai, Dina; De Simone, Gina

    2006-01-01

    Children with Asperger Syndrome present with significant social skills deficits, which may contribute to clinical problems such as anxiety, depression, and/or other behavioral disorders. This article provides a description of the nature of Asperger Syndrome and provides possible treatment interventions, specifically focusing on the efficacy of…

  15. Power Cards to Improve Conversational Skills in Adolescents with Asperger Syndrome

    Science.gov (United States)

    Davis, Kathy M.; Boon, Richard T.; Cihak, David F.; Fore, Cecil, III

    2010-01-01

    The purpose of this study was to examine the effects of Power Cards on the initiation and maintenance of conversational skills in students with Asperger syndrome. Three high school students with Asperger Syndrome participated in this study. Power Cards were used to prompt students' previously learned conversational skills in a multiple-baseline…

  16. Unveiling the Training Needs of the School Counselor: Implementing Effective Interventions with Students with Asperger Syndrome

    Science.gov (United States)

    Kincaid, Laura

    2012-01-01

    Purpose: The purpose of this study was to identify school counselors' specific training needs in order to provide leadership and consultation for effective interventions for students with Asperger syndrome. The study examined school counselors' level of knowledge, skill, and training in working with students with Asperger syndrome and…

  17. Career Development for College Students with Asperger's Syndrome

    Science.gov (United States)

    Mynatt, Blair Sumner; Gibbons, Melinda M.; Hughes, Amber

    2014-01-01

    An increasing number of students with Asperger's syndrome are entering college today. Students with Asperger's syndrome face complex symptomology such as difficulty with social skills, narrowed interests, sensory issues, and lack of self-awareness that may affect their ability to complete college and successfully enter the workforce.…

  18. Recognition of Facial Expressions and Prosodic Cues with Graded Emotional Intensities in Adults with Asperger Syndrome

    Science.gov (United States)

    Doi, Hirokazu; Fujisawa, Takashi X.; Kanai, Chieko; Ohta, Haruhisa; Yokoi, Hideki; Iwanami, Akira; Kato, Nobumasa; Shinohara, Kazuyuki

    2013-01-01

    This study investigated the ability of adults with Asperger syndrome to recognize emotional categories of facial expressions and emotional prosodies with graded emotional intensities. The individuals with Asperger syndrome showed poorer recognition performance for angry and sad expressions from both facial and vocal information. The group…

  19. The Quality of Life of Young Men with Asperger Syndrome: A Brief Report

    Science.gov (United States)

    Jennes-Coussens, Marieke; Magill-Evans, Joyce; Koning, Cyndie

    2006-01-01

    Factors influencing quality of life for persons with Asperger syndrome are not yet understood. Men, ages 18 to 21, completed the World Health Organization Quality Of Life measure, the Perceived Support Network Inventory, and a semi-structured interview. Asperger syndrome affects quality of life beyond the obvious social impact. The 12 men with…

  20. Children with High-Functioning Autism and Asperger's Syndrome: Can We Differentiate Their Cognitive Profiles?

    Science.gov (United States)

    Planche, Pascale; Lemonnier, Eric

    2012-01-01

    The aim of this study was to investigate whether children with high-functioning autism (HFA) and Asperger's syndrome (AS) can be differentiated from each other and from typically developing children on their cognitive profiles. The present study included a total of 45 participants: children with autism (high-functioning autism or Asperger's…

  1. Syndrome or Difference: A Critical Review of Medical Conceptualisations of Asperger's Syndrome

    Science.gov (United States)

    Wheeler, Marc

    2011-01-01

    We live in a world of vast social differences. People of different ages, cultures, religions, gender and sexual orientation have, and indeed are expected to have, distinct differences in their behaviour, and in the way that they see the world. Asperger's syndrome (AS) is no different. People with AS have different personality types and have…

  2. Asperger's syndrome with unusual cerebral pathology: Case report and literature review

    OpenAIRE

    Liu, Liqiong; Vo, Van; Ware, Marcus; Xiong, Zhenggang

    2012-01-01

    A case of Asperger's syndrome with unusual cerebral pathological changes is reported. A 22-year-old male had been having diagnostic Asperger's syndrome since the age of eight and had epilepsy during the past two years. Radiological studies revealed a focal intra-axial cortical and subcortical cerebral lesion with hyper-intensity and non-enhancing contrast in the left frontal lobe. Histological and immunohistochemical studies demonstrated that the lesion consisted of cortical laminar disorgani...

  3. Can asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies

    OpenAIRE

    Yu, Kevin K.; Cheung, Charlton; Chua, Siew E.; McAlonan, Gráinne M.

    2011-01-01

    Background: The question of whether Asperger syndrome can be distinguished from autism has attracted much debate and may even incur delay in diagnosis and intervention. Accordingly, there has been a proposal for Asperger syndrome to be subsumed under autism in the forthcoming Diagnostic and Statistical Manual of Mental Disorders, fifth edition, in 2013. One approach to resolve this question has been to adopt the criterion of absence of clinically significant language or cognitive delay - esse...

  4. Social attribution processes and comorbid psychiatric symptoms in children with Asperger syndrome

    OpenAIRE

    Meyer, Jessica A.; Mundy, Peter C.; Van Hecke, Amy Vaughan; Durocher, Jennifer Stella

    2006-01-01

    The factors that place children with Asperger syndrome at risk for comorbid psychiatric symptoms, such as anxiety and depression, remain poorly understood. We investigated the possibility that the children’s emotional and behavioral difficulties are associated with social information and attribution processing. Participants were children with either Asperger syndrome (n = 31) or typical development (n = 33).To assess social information and attribution processing, children responded to hypothe...

  5. Photoanthropometric Study of Dysmorphic Features of the Face in Children with Autism and Asperger Syndrome

    OpenAIRE

    Katarzyna Ziora; Agnieszka Kapinos- Gorczyca; Piotr Gorczyca; Joanna Oświęcimska

    2012-01-01

    Objective: Childhood autism is a neurodevelopmental disorder characterized by impairments in social interactions, verbal and non-verbal communication and by a pattern of stereotypical behaviors and interests. The aim of this study was to estimate the dysmorphic facial features of children with autism and children with Asperger syndrome . Methods: The examination was conducted on 60 children (30 with childhood autism and 30 with Asperger syndrome). The photo anthropometric method used in this ...

  6. Psychotherapy with people with Asperger Syndrome; exploring ways to improve client and therapist well-being

    OpenAIRE

    Chalk, Matty

    2012-01-01

    It is well documented that people with Asperger Syndrome show a propensity to mental health problems (e.g. Tantam, 1988); one contributor possibly being difficulties with social interaction (Frith, 2004). People with Asperger Syndrome and mental health problems may therefore require support, one form being psychotherapy (e.g. Schopler & Mesibov, 1983). However, despite the possible need of this population and the recent drives towards improving access to psychological therapies to the wider ...

  7. Asperger Syndrome In Adulthood: A Review

    OpenAIRE

    Ali Tufan

    2011-01-01

    Asperger’s syndrome (AS) is one of the disorders classified under pervasive developmental disorders. Individuals with AS have problems in social interaction, unusual special interests, and a tendency to ritualized behavior. AS is a chronic disorder that affects the social, occupational, sexual and psychological functionality of individiuals with AS. This review was prepared on the basis of a selective literature review by Pubmed and information in relevant reference books. As a result, ...

  8. Asperger Syndrome In Adulthood: A Review

    Directory of Open Access Journals (Sweden)

    Ali Tufan

    2011-09-01

    Full Text Available Asperger’s syndrome (AS is one of the disorders classified under pervasive developmental disorders. Individuals with AS have problems in social interaction, unusual special interests, and a tendency to ritualized behavior. AS is a chronic disorder that affects the social, occupational, sexual and psychological functionality of individiuals with AS. This review was prepared on the basis of a selective literature review by Pubmed and information in relevant reference books. As a result, longitudinal studies are deemed to be necessary to be able understand the features of AS in adulthood.

  9. Asperger Syndrome and Schizophrenia: A Comparative Neuropsychological Study.

    Science.gov (United States)

    Marinopoulou, Maria; Lugnegård, Tove; Hallerbäck, Maria Unenge; Gillberg, Christopher; Billstedt, Eva

    2016-07-01

    There has been an increasing interest in possible connections between autism spectrum disorder (ASD) and schizophrenia in the last decade. Neuropsychological comparison studies have, however, been few. The present study examined similarities and differences in intellectual and executive functioning between adults with Asperger syndrome (AS) and adults with schizophrenic psychosis (SP). A group with AS and a group with SP were assessed neuropsychologically with WAIS-III and D-KEFS. Similarities were found between groups, as displayed by an uneven cognitive profile, limitations in working memory, processing speed and some aspects of executive functioning. Full Scale IQ was higher in the AS group. These results add to the current research illuminating similarities and differences between ASD and schizophrenia on a cognitive level. PMID:26936160

  10. Social cognition and communication skills in Asperger syndrome young adults

    Directory of Open Access Journals (Sweden)

    Mónica Figueira

    2013-11-01

    Full Text Available The aim of this study is to compare patients with Asperger syndrome (AS and control participants on social cognition tasks and communication skills. Twenty young adults were assessed in three social cognition domains; recognition of basic emotions, recognition of complex emotions and Theory of Mind (ToM. In addition participants completed a self-report questionnaire as a measure of social communication skills. The results indicate that adults with AS perform below neurotypical control participants in emotion processing, ToM and communication skills. There were no significant correlations between the variables of social cognition and communication skills in the group of AS. Taken together, results suggest that people with a diagnosis of AS present a deficit in ToM and emotional processing as well as in communication skills. However, it was not possible to identify a significant association between the variables of social cognition and communication skills.

  11. Is synaesthesia more common in patients with Asperger syndrome?

    Directory of Open Access Journals (Sweden)

    Janina eNeufeld

    2013-12-01

    Full Text Available There is increasing evidence from case reports that synaesthesia is more common in individuals with autism spectrum conditions (ASC. Further, genes related to synaesthesia have also been found to be linked to ASC and, similar to synaesthetes, individuals with ASC show altered brain connectivity and unusual brain activation during sensory processing. However, up to now a systematic investigation of whether synaesthesia is more common in ASC patients is missing.The aim of the current pilot study was to test this hypothesis by investigating a group of patients diagnosed with Asperger Syndrome (AS using questionnaires and standard consistency tests in order to classify them as grapheme-colour synaesthetes. The results indicate that there are indeed many more grapheme-colour synaesthetes among AS patients. This finding is discussed in relation to different theories regarding the development of synaesthesia as well as altered sensory processing in autism.

  12. Síndrome de Asperger e TOC: comorbidade ou unidade? Asperger syndrome and OCD: comorbidity or unity?

    Directory of Open Access Journals (Sweden)

    José Maria Aranha Fonseca

    2007-01-01

    Full Text Available Comportamentos repetitivos, estereotipias e interesses restritos são alguns dos principais sintomas que compõem o transtorno de Asperger. Todavia, até que ponto é possível diferenciá-los de sintomas obsessivo-compulsivos que preencham critérios para transtorno obsessivo-compulsivo (TOC? Muitas vezes, não é possível. Este trabalho relata o caso de um paciente com síndrome de Asperger e TOC. Abordamos até que ponto é realmente importante a distinção de um TOC como comorbidade distinta do Asperger, bem como nossa conduta terapêutica, na qual um inibidor seletivo da recaptura de serotonina (ISRS em doses altas (fluoxetina foi fundamental para melhor adaptação do paciente a suas funções socioocupacionais, melhorando significativamente sua qualidade de vida.Repetitive behavior, stereotypies and restricted interests are some of the main symptoms that compound the Asperger’s disorder. However, until what point is possible to differentiate them from obsessive-compulsive symptoms that meet criteria for obsessive-compulsive disorder (OCD? Many times, that’s not possible. This work reports the case of a patient with Asperger syndrome and OCD. We bring up until what point is really important the distinction of OCD as a comorbidity different from Asperger, and also our therapeutic conduct, in which high doses of a selective serotonin reuptake inhibitor - SSRI - (fluoxetine was fundamental to a better socio-occupational adjustment of the patient, significantly improving his quality of life.

  13. A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis

    OpenAIRE

    Barahona-Corrêa, J. B.; Filipe, Carlos N.

    2016-01-01

    First described in 1944 by Hans Asperger (1944), it was not before 1994 that Asperger Syndrome (AS) was included in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual’s fifth edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but...

  14. A Concise History of Asperger Syndrome: the short reign of a troublesome diagnosis

    OpenAIRE

    Bernardo eBarahona-Correa; Carlos Nunes Filipe

    2016-01-01

    First described in 1944 by Hans Asperger, it was not before 1994 that Asperger Syndrome (AS) was included in the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual’s 5th edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but also displa...

  15. DSM-IV-Defined Asperger Syndrome: Cognitive, Behavioral and Early History Differentiation from High-Functioning Autism.

    Science.gov (United States)

    Ozonoff, Sally; South, Mikle; Miller, Judith N.

    2000-01-01

    This study compared 23 children with high-functioning autism with 12 children with Asperger syndrome using DSM-IV diagnostic criteria. Findings indicated few group differences in current functioning but many early history differences. The Asperger syndrome group generally demonstrated less severe early symptoms, a milder developmental course, and…

  16. Using Symbolic Interactionism Insights as an Approach to Helping the Individual with Asperger's Syndrome Overcome Barriers to Social Inclusion

    Science.gov (United States)

    Hughes, Paul

    2016-01-01

    This article outlines a case for using symbolic interactionism as a tool to help individuals with Asperger's syndrome reconcile situations in which communication might prove challenging. This study builds on previous work carried out by the author which describes an autoethnographical approach to help the individual with Asperger's syndrome gain…

  17. School Administrator Assessment of the Personality Traits of General Education Teachers for Suitability to Teach a Student with Asperger's Syndrome

    Science.gov (United States)

    Bernard, Arthur Ellis

    2011-01-01

    Most students with Asperger's syndrome are taught in general education classes by teachers who do not have special education training and it is the usually the administrator's responsibility to determine which general education teacher will teach a child with Asperger's syndrome. It is likely that most such decisions rely heavily on the…

  18. Effective Methylphenidate Treatment of an Adult Aspergers Syndrome and a Comorbid ADHD: A Clinical Investigation with fMRI

    Science.gov (United States)

    Roy, Mandy; Dillo, Wolfgang; Bessling, Svenja; Emrich, Hinderk M.; Ohlmeier, Martin D.

    2009-01-01

    Objective: Aspergers Syndrome can present as comorbid with attention-deficit/hyperactivity disorder (ADHD). Very few cases of the assessment and treatment of this comorbidity in adulthood are described in the research literature. Method: A 26-year-old patient as suffering from ADHD in combination with Aspergers Syndrome is diagnosed. Treatment is…

  19. Social Perception and WAIS-IV Performance in Adolescents and Adults Diagnosed with Asperger's Syndrome and Autism

    Science.gov (United States)

    Holdnack, James; Goldstein, Gerald; Drozdick, Lisa

    2011-01-01

    Previous research using the Wechsler scales has identified areas of cognitive weaknesses in children, adolescents, and adults diagnosed with Autism or Asperger's syndrome. The current study evaluates cognitive functioning in adolescents and adults diagnosed with Autism or Asperger's syndrome using the Wechsler Adult Intelligence Scale-Fourth…

  20. Insomnia is a frequent finding in adults with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    von Wendt Lennart

    2003-10-01

    Full Text Available Abstract Background Asperger syndrome (AS is a neurodevelopmental disorder belonging to autism spectrum disorders with prevalence rate of 0,35% in school-age children. It has been most extensively studied in childhood while there is scarcity of reports concerning adulthood of AS subjects despite the lifelong nature of this syndrome. In children with Asperger syndrome the initiation and continuity of sleep is disturbed because of the neuropsychiatric deficits inherent of AS. It is probable that sleep difficulties are present in adulthood as well. Our hypothesis was that adults with AS suffer from difficulty in initiating and maintaining sleep and nonrestorative sleep (insomnia. Methods 20 AS without medication were compared with 10 healthy controls devoid of neuropsychiatric anamnesis. Clinical examination, blood test battery and head MRI excluded confounding somatic illnesses. Structured psychiatric interview for axis-I and axis-II disorders were given to both groups as well as Beck Depression Inventory and Wechsler adult intelligence scale, revised version. Sleep quality was assessed with sleep questionnaire, sleep diary during 6 consecutive days and description of possible sleep problems by the participants own words was requested. Results compared with controls and with normative values of good sleep, AS adults had frequent insomnia. In sleep questionnaire 90% (18/20, in sleep diary 75% (15/20 and in free description 85% (17/20 displayed insomnia. There was a substantial psychiatric comorbidity with only 4 AS subject devoid of other axis-I or axis-II disorders besides AS. Also these persons displayed insomnia. It can be noted that the distribution of psychiatric diagnoses in AS subjects was virtually similar to that found among patient with chronic insomnia. Conclusions the neuropsychiatric deficits inherent of AS predispose both to insomnia and to anxiety and mood disorders. Therefore a careful assessment of sleep quality should be an

  1. Zur Diagnostik und Ätiologie des Asperger-Syndroms bei Kindern und Jugendlichen

    OpenAIRE

    Kamp-Becker, Inge; Mattejat, Fritz; REMSCHMIDT, HELMUT

    2004-01-01

    Das Asperger-Syndrom ist eine tiefgreifende Entwicklungsstörung mit eine Kontaktund Kommunikationsstörung, einer qualitativen Beeinträchtigung des Interaktionsverhaltens, mangelndem Einfühlungsvermögen, motorischen Auffälligkeiten und ausgeprägten Sonderinteressen. Die Diagnosekriterien und die diagnostischen Methoden werden ausführlich erläutert. Bis heute sind die Validität und die Ätiologie des Asperger-Syndrom ungeklärt. Zum frühkindlichen Autismus (Kanner-Syndrom) gibt es dagegen vie...

  2. Screening for Asperger Syndrome in School-Age Children: Issues and Instruments

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    Reilly, Colin; Campbell, Audrey; Keran, Patricia

    2009-01-01

    Many children with Asperger syndrome are not identified prior to school entry, and difficulties associated with the condition may only become evident when a child enters school. Failure to identify children with the syndrome may lead to increased risk for psychopathology, and lack of understanding of the reasons for social and communicative…

  3. Unique Theory of Mind Differentiation in Children with Autism and Asperger Syndrome

    Directory of Open Access Journals (Sweden)

    Michele Tine

    2012-01-01

    Full Text Available This study was designed to determine if ToM abilities of children with autism and Asperger syndrome differentiate into Intrapersonal ToM and Social ToM. A battery of Social and Intrapersonal ToM tasks was administered to 39 children with autism and 34 children with Asperger syndrome. For both groups of children, ToM differentiated and Intrapersonal ToM was stronger than Social ToM. This asymmetry was greater for children with autism, whose Social ToM was especially weak. These results support a differentiated, as opposed to integrated, ToM. Moreover, the findings provide a more thorough understanding of the cognitive abilities associated with autism and Asperger syndrome.

  4. A Pooled Genome-Wide Association Study of Asperger Syndrome.

    Directory of Open Access Journals (Sweden)

    Varun Warrier

    Full Text Available Asperger Syndrome (AS is a neurodevelopmental condition characterized by impairments in social interaction and communication, alongside the presence of unusually repetitive, restricted interests and stereotyped behaviour. Individuals with AS have no delay in cognitive and language development. It is a subset of Autism Spectrum Conditions (ASC, which are highly heritable and has a population prevalence of approximately 1%. Few studies have investigated the genetic basis of AS. To address this gap in the literature, we performed a genome-wide pooled DNA association study to identify candidate loci in 612 individuals (294 cases and 318 controls of Caucasian ancestry, using the Affymetrix GeneChip Human Mapping version 6.0 array. We identified 11 SNPs that had a p-value below 1x10-5. These SNPs were independently genotyped in the same sample. Three of the SNPs (rs1268055, rs7785891 and rs2782448 were nominally significant, though none remained significant after Bonferroni correction. Two of our top three SNPs (rs7785891 and rs2782448 lie in loci previously implicated in ASC. However, investigation of the three SNPs in the ASC genome-wide association dataset from the Psychiatric Genomics Consortium indicated that these three SNPs were not significantly associated with ASC. The effect sizes of the variants were modest, indicating that our study was not sufficiently powered to identify causal variants with precision.

  5. [Asperger's syndrome: continuum or spectrum of autistic disorders?].

    Science.gov (United States)

    Bryńska, Anita

    2011-01-01

    Pervasive Developmental Disorders (PPD) refers to the group of disorders characterised by delayed or inappropriate development of multiple basic functions including socialisation, communication, behaviour and cognitive functioning. The term,,autistic spectrum disorders" was established as a result of the magnitude of the intensity of symptoms and their proportions observed in all types of pervasive developmental disorders. Asperger's Syndrome (AS) remains the most controversial diagnosis in terms of its place within autism spectrum disorders. AS if often described as an equivalent of High Functioning Autism (HFA) or as a separate spectrum-related disorder with unique diagnostic criteria. Another important issue is the relationship between AS and speech disorders. Although it is relatively easy to draw a line between children with classical autism and speech disorders, the clear cut frontiers between them still remain to be found. The main distinguishing feature is the lack of stereotypic interests and unimpaired social interaction observed in children with speech disorders, such as semantic-pragmatic disorder. PMID:22220491

  6. Removal of Asperger's syndrome from the DSM V: community response to uncertainty.

    Science.gov (United States)

    Parsloe, Sarah M; Babrow, Austin S

    2016-01-01

    The May 2013 release of the new version of the Diagnostic and Statistical Manual of Mental Disorders (DSM V) subsumed Asperger's syndrome under the wider diagnostic label of autism spectrum disorder (ASD). The revision has created much uncertainty in the community affected by this condition. This study uses problematic integration theory and thematic analysis to investigate how participants in Wrong Planet, a large online community associated with autism and Asperger's syndrome, have constructed these uncertainties. The analysis illuminates uncertainties concerning both the likelihood of diagnosis and value of diagnosis, and it details specific issues within these two general areas of uncertainty. The article concludes with both conceptual and practical implications. PMID:26400415

  7. The level and nature of autistic intelligence II: what about Asperger syndrome?

    Directory of Open Access Journals (Sweden)

    Isabelle Soulières

    Full Text Available A distinctively uneven profile of intelligence is a feature of the autistic spectrum. Within the spectrum, Asperger individuals differ from autistics in their early speech development and in being less likely to be characterized by visuospatial peaks. While different specific strengths characterize different autistic spectrum subgroups, all such peaks of ability have been interpreted as deficits: isolated, aberrant, and irreconcilable with real human intelligence. This view has recently been challenged by findings of autistic strengths in performance on Raven's Progressive Matrices (RPM, an important marker of general and fluid intelligence. We investigated whether these findings extend to Asperger syndrome, an autistic spectrum subgroup characterized by verbal peaks of ability, and whether the cognitive mechanisms underlying autistic and Asperger RPM performance differ. Thirty-two Asperger adults displayed a significant advantage on RPM over Wechsler Full-Scale and Performance scores relative to their typical controls, while in 25 Asperger children an RPM advantage was found over Wechsler Performance scores only. As previously found with autistics, Asperger children and adults achieved RPM scores at a level reflecting their Wechsler peaks of ability. Therefore, strengths in RPM performance span the autistic spectrum and imply a common mechanism advantageously applied to different facets of cognition. Autistic spectrum intelligence is atypical, but also genuine, general, and underestimated.

  8. Challenges in Social Communication in Asperger Syndrome and High-Functioning Autism

    Science.gov (United States)

    Rubin, Emily; Lennon, Laurie

    2004-01-01

    Despite the inclusion of Asperger syndrome in the Diagnostic and Statistical Manual of Mental Disorders--Fourth Edition (DSM-IV) American Psychiatric Association [APA], 1994) 10 years ago, there is ongoing debate regarding its validity as a diagnostic construct, particularly relative to the diagnosis of autistic disorder when it is not accompanied…

  9. An Integrated Literature Review on the Adaptive Behavior of Individuals with Asperger Syndrome

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    Lee, Hyo Jung; Park, Hye Ran

    2007-01-01

    The diagnostic definition of Asperger syndrome (AS) is surrounded by debate and controversy, because it does not address many of the broader characteristics of individuals with AS. For example, neither the "Diagnostic and Statistical Manual of Mental Disorders," 4th edition, nor the "International Classification of Diseases," 10th revision,…

  10. Confusion and Inconsistency in Diagnosis of Asperger Syndrome: A Review of Studies from 1981 to 2010

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    Sharma, Shilpi; Woolfson, Lisa Marks; Hunter, Simon C.

    2012-01-01

    This paper presents a review of past and current research on the diagnosis of Asperger syndrome (AS) in children. It is suggested that the widely used criteria for diagnosing AS in the "Diagnostic and Statistical Manual of Mental Disorders" (DSM)-IV are insufficient and invalid for a reliable diagnosis of AS. In addition, when these diagnostic…

  11. Brief Report: Insight into Illness and Social Attributional Style in Asperger's Syndrome

    Science.gov (United States)

    Didehbani, Nyaz; Shad, Mujeeb U.; Kandalaft, Michelle R.; Allen, Tandra T.; Tamminga, Carol A.; Krawczyk, Daniel C.; Chapman, Sandra B.

    2012-01-01

    A number of psychiatric illnesses have been recognized to have some level of insight deficits, including developmental disorders, such as Asperger's Syndrome (ASP). However insight into illness has not been empirically investigated in ASP and little research has examined how individuals with ASP view their deficits. This is the first study to…

  12. Brief Report: Imitation of Meaningless Gestures in Individuals with Asperger Syndrome and High-Functioning Autism

    Science.gov (United States)

    Stieglitz Ham, Heidi; Corley, Martin; Rajendran, Gnanathusharan; Carletta, Jean; Swanson, Sara

    2008-01-01

    Nineteen people with Asperger syndrome (AS)/High-Functioning Autism (HFA) (ages 7-15) were tested on imitation of two types of meaningless gesture: hand postures and finger positions. The individuals with AS/HFA achieved lower scores in the imitation of both hand and finger positions relative to a matched neurotypical group. The between-group…

  13. A New Computerised Advanced Theory of Mind Measure for Children with Asperger Syndrome: The ATOMIC

    Science.gov (United States)

    Beaumont, Renae B.; Sofronoff, Kate

    2008-01-01

    This study examined the ability of children with Asperger Syndrome (AS) to attribute mental states to characters in a new computerised, advanced theory of mind measure: The Animated Theory of Mind Inventory for Children (ATOMIC). Results showed that children with AS matched on IQ, verbal comprehension, age and gender performed equivalently on…

  14. Faux Pas Detection and Intentional Action in Asperger Syndrome. A Replication on a French Sample

    Science.gov (United States)

    Zalla, Tiziana; Sav, Anca-Maria; Stopin, Astrid; Ahade, Sabrina; Leboyer, Marion

    2009-01-01

    In the present study, we investigated mindreading abilities in a group of adults with Asperger Syndrome (AS) by using the faux pas task, an advanced test of theory of mind (Baron-Cohen et al. (1999). "Journal of Autism and Developmental Disorders, 29," 407-418). The faux pas is a particular case of a non-intentional action reflecting an…

  15. Narrative Competence and "Internal State Language" of Children with Asperger Syndrome and ADHD

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    Rumpf, Anna-Lena; Kamp-Becker, Inge; Becker, Katja; Kauschke, Christina

    2012-01-01

    The central question of the present study was whether there are differences between children with Asperger Syndrome (AS), children with attention deficit hyperactivity disorder (ADHD) and healthy controls (HC) with respect to the organization of narratives and their verbalization of internal states. Oral narrations of a wordless picture book…

  16. Recognition of Facially Expressed Emotions and Visual Search Strategies in Adults with Asperger Syndrome

    Science.gov (United States)

    Falkmer, Marita; Bjallmark, Anna; Larsson, Matilda; Falkmer, Torbjorn

    2011-01-01

    Can the disadvantages persons with Asperger syndrome frequently experience with reading facially expressed emotions be attributed to a different visual perception, affecting their scanning patterns? Visual search strategies, particularly regarding the importance of information from the eye area, and the ability to recognise facially expressed…

  17. Parents of Children with Asperger Syndrome or with Learning Disabilities: Family Environment and Social Support

    Science.gov (United States)

    Heiman, Tali; Berger, Ornit

    2008-01-01

    The study examined the family environment and perceived social support of 33 parents with a child diagnosed with Asperger syndrome and 43 parents with a child with learning disability, which were compared to 45 parents of children without disabilities as a control group. Parents completed the Family Environment Scale and Social Support Scale…

  18. Finding Meaning in Parenting a Child with Asperger Syndrome: Correlates of Sense Making and Benefit Finding

    Science.gov (United States)

    Pakenham, Kenneth I.; Sofronoff, Kate; Samios, Christina

    2004-01-01

    This study explored the nature of two construals of meaning, benefit finding and sense making, in parents of a child with Asperger syndrome, and examined relations between both meaning constructs and the Double ABCX family stress model variables (initial stressor and pile-up of demands, appraisal, social support, coping strategies and adjustment)…

  19. Reducing the Threatening and Aggressive Behavior of a Middle School Student with Asperger's Syndrome

    Science.gov (United States)

    Sansosti, Frank J.

    2012-01-01

    The purpose of this case study was to demonstrate the success of a multicomponent intervention to reduce the threatening and aggressive behaviors of a middle school student with Asperger's syndrome. The author provides information pertaining to the student and details the procedures for developing a packaged intervention. Results of this approach,…

  20. Brief Report: Should Asperger Syndrome Be Excluded from the Forthcoming DSM-V?

    Science.gov (United States)

    Kaland, Nils

    2011-01-01

    Asperger syndrome (AS) is a "pervasive developmental disorder," characterized by social impairments and focused, circumscribed interests and activities in the absence of significant language impairment and cognitive delay. Since its inclusion in the DSM-IV, there has been a dramatic increase in its recognition both in children and adults. Some…

  1. The Needs of College Students with Autism Spectrum Disorders and Asperger's Syndrome

    Science.gov (United States)

    Cullen, Jennifer A.

    2015-01-01

    Many colleges and universities have seen increases in students identified as having autism spectrum disorders (ASD) or Asperger's syndrome (AS). The purpose of this study was to analyze the needs of college students with autism spectrum disorders. The study implemented a naturalistic inquiry design incorporating three data collection formats. A…

  2. Moving beyond the Minimum: Socially Just Pedagogies and Asperger's Syndrome in UK Higher Education

    Science.gov (United States)

    Madriaga, Manuel; Goodley, Dan

    2010-01-01

    A year-long longitudinal study was conducted to gain insight into the lives of eight students who had a label of Asperger's syndrome during their transitions into higher education in the UK. Reflecting on life history data, the findings suggest that universities might actually be maintaining and (re)producing barriers that perpetuate the exclusion…

  3. A Reflective Conversation with Terry Friedrichs on Teaching Academics to Gifted Students with Asperger Syndrome

    Science.gov (United States)

    Friedrichs, Terence Paul; Shaughnessy, Michael F.

    2015-01-01

    In this reflective interview with Terry Friedrichs--a hands-on academic-learning specialist and researcher with gifted students with Asperger Syndrome--he defines these pupils, describes their "straightforward" and confusing traits, and recounts his initial and later instructional experiences with them over several decades. The piece…

  4. Functional Analysis of Inappropriate Social Interactions in Students with Asperger's Syndrome

    Science.gov (United States)

    Roantree, Christina F.; Kennedy, Craig H.

    2012-01-01

    We analyzed the inappropriate social interactions of 3 students with Asperger's syndrome whose behavior was maintained by social positive reinforcement. We tested whether inappropriate social behavior was sensitive to social positive reinforcement contingencies and whether such contingencies could be reversed to increase the probability of…

  5. Instructional Accommodations for Students with Asperger Syndrome in the General High School Classroom

    Science.gov (United States)

    Baylis, Myrna

    2011-01-01

    General education teachers in the secondary sector are held responsible for adapting their lessons and classroom environment for students with Asperger Syndrome. With the growing number of students with Autism Spectrum Disorder being placed in general education classrooms, teachers are faced with yet another challenge in making their curriculum…

  6. Cognitive and Academic Distinctions between Gifted Students with Autism and Asperger Syndrome

    Science.gov (United States)

    Foley-Nicpon, Megan; Assouline, Susan G.; Stinson, Rebecca D.

    2012-01-01

    The cognitive and academic profiles of high ability students with autism spectrum disorder were examined. Inclusion criteria were a diagnosis of autism (high functioning) or Asperger syndrome and at least one ability and/or achievement index standard score of 120 or above. Results indicated that despite the restricted range of cognitive abilities,…

  7. From Acoustics to Grammar: Perceiving and Interpreting Grammatical Prosody in Adolescents with Asperger Syndrome

    Science.gov (United States)

    Chevallier, Coralie; Noveck, Ira; Happe, Francesca; Wilson, Deirdre

    2009-01-01

    We report findings concerning the understanding of prosody in Asperger Syndrome (AS), a topic which has attracted little attention and led to contradictory results. Ability to understand grammatical prosody was tested in three novel experiments. Experiment 1 assessed the interpretation of word stress, Experiment 2 focused on grammatical pauses,…

  8. Spontaneous Attention to Faces in Asperger Syndrome Using Ecologically Valid Static Stimuli

    Science.gov (United States)

    Hanley, Mary; McPhillips, Martin; Mulhern, Gerry; Riby, Deborah M.

    2013-01-01

    Previous eye tracking research on the allocation of attention to social information by individuals with autism spectrum disorders is equivocal and may be in part a consequence of variation in stimuli used between studies. The current study explored attention allocation to faces, and within faces, by individuals with Asperger syndrome using a range…

  9. Life at University with Asperger Syndrome: A Comparison of Student and Staff Perspectives

    Science.gov (United States)

    Knott, Fiona; Taylor, Angela

    2014-01-01

    Although increasing numbers of students with disabilities are accessing higher education, there is relatively little information about the needs of students with Asperger syndrome (AS). Crucially, students themselves have rarely been included in research examining their needs or the supports they might find helpful. Three focus groups, one with…

  10. Pragmatic Inferences in High-Functioning Adults with Autism and Asperger Syndrome

    Science.gov (United States)

    Pijnacker, Judith; Hagoort, Peter; Buitelaar, Jan; Teunisse, Jan-Pieter; Geurts, Bart

    2009-01-01

    Although people with autism spectrum disorders (ASD) often have severe problems with pragmatic aspects of language, little is known about their pragmatic reasoning. We carried out a behavioral study on high-functioning adults with autistic disorder (n = 11) and Asperger syndrome (n = 17) and matched controls (n = 28) to investigate whether they…

  11. Risk Factors for Autism and Asperger Syndrome: Perinatal Factors and Migration

    Science.gov (United States)

    Haglund, Nils G. S.; Kallen, Karin B. M.

    2011-01-01

    Using the Swedish Medical Birth Registry (MBR), obstetrical and demographic information was retrieved for 250 children with autism or Asperger syndrome who were born in Malmoe, Sweden, and enrolled at the local Child and Youth Habilitation Center. The reference group consisted of all children born in Malmoe during 1980-2005. Obstetric…

  12. Stimulus-Reward Association and Reversal Learning in Individuals with Asperger Syndrome

    Science.gov (United States)

    Zalla, Tiziana; Sav, Anca-Maria; Leboyer, Marion

    2009-01-01

    In the present study, performance of a group of adults with Asperger Syndrome (AS) on two series of object reversal and extinction was compared with that of a group of adults with typical development. Participants were requested to learn a stimulus-reward association rule and monitor changes in reward value of stimuli in order to gain as many…

  13. Exploring Language Profiles for Children with ADHD and Children with Asperger Syndrome

    Science.gov (United States)

    Helland, Wenche Andersen; Biringer, Eva; Helland, Turid; Heimann, Mikael

    2012-01-01

    Objective: The aims of the present study was to investigate communication impairments in a Norwegian sample of children with ADHD and children with Asperger syndrome (AS) and to explore whether children with ADHD can be differentiated from children with AS in terms of their language profiles on the Norwegian adaptation of the Children's…

  14. Relationship between Motor Skill Impairment and Severity in Children with Asperger Syndrome

    Science.gov (United States)

    Hilton, Claudia; Wente, Lyndsay; LaVesser, Patricia; Ito, Max; Reed, Carol; Herzberg, Georgiana

    2007-01-01

    This study examined the correlation between severity and motor impairment in children with Asperger syndrome (AS). Children, ages 6-12 with AS (N = 51) and a control group of typical children (N = 56), were assessed using the Social Responsiveness Scale (SRS) and the Movement Assessment Battery For Children (MABC). A bivariate correlational design…

  15. White Matter Integrity in Asperger Syndrome: A Preliminary Diffusion Tensor Magnetic Resonance Imaging Study in Adults

    NARCIS (Netherlands)

    O.J.N. Bloemen; Q. Deeley; F. Sundram; E.M. Daly; G.J. Barker; D.K. Jones; T.A.M.J. van Amelsvoort; N. Schmitz; D. Robertson; K.C. Murphy; D.G.M. Murphy

    2010-01-01

    Background: Autistic Spectrum Disorder (ASD), including Asperger syndrome and autism, is a highly genetic neurodevelopmental disorder. There is a consensus that ASD has a biological basis, and it has been proposed that it is a "connectivity" disorder. Diffusion Tensor Magnetic Resonance Imaging (DT-

  16. Treatment of Chronic Skin-Picking in an Adolescent With Asperger Syndrome and Borderline Intellectual Disability

    NARCIS (Netherlands)

    Lang, R.; Didden, H.C.M.; Sigafoos, J.; Rispoli, M.; Regester, A.; Lancioni, G.E.

    2009-01-01

    We present the case of a 17-year-old girl with Asperger syndrome and borderline intellectual disability with a 5-year history of chronic skin-picking. Our intervention approach included an initial functional assessment to identify variables maintaining skin-picking, followed by evaluation of a behav

  17. Mental and Behavioral Symptoms of Person's with Asperger's Syndrome: Relationships with Social Isolation and Handicaps

    Science.gov (United States)

    Tani, Masayuki; Kanai, Chieko; Ota, Haruhisa; Yamada, Takashi; Watanabe, Hiromi; Yokoi, Hideki; Takayama, Yuko; Ono, Taisei; Hashimoto, Ryuichiro; Kato, Nobumasa; Iwanami, Akira

    2012-01-01

    People with Asperger's syndrome (AS) experience mental comorbidities, and behavioral symptoms that can deepen social isolation and handicaps. We compared the frequency of mental and behavioral symptoms, motor abnormality, and life history between adults with AS and those with no mental disorders but with disturbance of social functions and…

  18. Avoidance of Emotionally Arousing Stimuli Predicts Social-Perceptual Impairment in Asperger's Syndrome

    Science.gov (United States)

    Corden, Ben; Chilvers, Rebecca; Skuse, David

    2008-01-01

    We combined eye-tracking technology with a test of facial affect recognition and a measure of self-reported social anxiety in order to explore the aetiology of social-perceptual deficits in Asperger's syndrome (AS). Compared to controls matched for age, IQ and visual-perceptual ability, we found a group of AS adults was impaired in their…

  19. Gifted Students with Asperger Syndrome: Strategies for Strength-Based Programming

    Science.gov (United States)

    Bianco, Margarita; Carothers, Douglas E.; Smiley, Lydia R.

    2009-01-01

    Gifted students with Asperger syndrome (AS) frequently exhibit behaviors that puzzle and challenge teachers and other professionals. They display many of the behaviors typically associated with AS and therefore receive educational interventions designed to address their deficit areas. Often lacking is strength-based programming--that is,…

  20. Functional analysis of insistence on sameness in an 11-year old boy with Asperger syndrome

    NARCIS (Netherlands)

    Ollington, N.; Green, V.A.; O'Reilly, M.F.; Lancioni, G.E.; Didden, H.C.M.

    2012-01-01

    Objective: To identify the functional properties of insistence on sameness associated with autism spectrum disorders. Method: An 11-year-old boy with Asperger syndrome was observed during play where scenarios (mistakes, misplaced items, interrupted activity) were created to correspond with parent-re

  1. Hypercholesterolemia in Asperger syndrome: independence from lifestyle, obsessive-compulsive behavior, and social anxiety.

    Science.gov (United States)

    Dziobek, Isabel; Gold, Stefan M; Wolf, Oliver T; Convit, Antonio

    2007-01-15

    We report on elevated total cholesterol and low-density lipoprotein (LDL) levels in 22 individuals with Asperger syndrome compared with well-matched controls, after accounting for lifestyle variables and clinical symptomatology that could affect them. A potential role for dyslipidemia in the pathogenesis of some forms of autism is discussed. PMID:17123635

  2. Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome

    Science.gov (United States)

    Merchan-Naranjo, Jessica; Mayoral, Maria; Rapado-Castro, Marta; Llorente, Cloe; Boada, Leticia; Arango, Celso; Parellada, Mara

    2012-01-01

    Asperger syndrome (AS) patients show heterogeneous intelligence profiles and the validity of short forms for estimating intelligence has rarely been studied in this population. We analyzed the validity of Wechsler Intelligence Scale (WIS) short forms for estimating full-scale intelligence quotient (FSIQ) and assessing intelligence profiles in 29…

  3. Physical Fitness and Physical Activity in Adolescents with Asperger Syndrome: A Comparative Study

    Science.gov (United States)

    Borremans, Erwin; Rintala, Pauli; McCubbin, Jeffrey A.

    2010-01-01

    While physical activity is beneficial for youth with developmental disabilities, little is known about those individuals' fitness profile and levels of activity. Therefore the purpose of this study was to investigate the physical fitness profile and physical activity level of 30 adolescents with and without Asperger syndrome (AS). Evaluations were…

  4. A Social-Behavioral Learning Strategy Intervention for a Child with Asperger Syndrome: Brief Report

    Science.gov (United States)

    Bock, Marjorie A.

    2007-01-01

    This study examined the effect of a social-behavioral learning strategy intervention (Stop-Observe-Deliberate-Act; SODA) on the social interaction skills of one middle school student with Asperger syndrome (AS). More specifically, the study investigated the effect of SODA training on the ability of one student with AS to participate in cooperative…

  5. Profiles of Social Communicative Competence in Middle School Children with Asperger Syndrome: Two Case Studies

    Science.gov (United States)

    Bellon-Harn, Monica L.; Harn, William E.

    2006-01-01

    Among characteristics of children diagnosed with Asperger syndrome (AS) are difficulties in social communication. This study describes the social communicative competence of two middle school children with AS participating in conversations in three different situational contexts. The conversations were transcribed and submitted to three kinds of…

  6. Social Comparison Processes and Depressive Symptoms in Children and Adolescents with Asperger Syndrome

    Science.gov (United States)

    Hedley, Darren; Young, Robyn

    2006-01-01

    The present study investigated the relationship between social comparison processes and depressive symptoms in 36 participants (34 males and two females) aged 10 to 16 years with Asperger syndrome. Participants completed the Social Comparison Scale and the Children's Depression Inventory. Depressive symptoms were significantly correlated with the…

  7. Understanding the Friendship Processes of Individuals with Asperger's Syndrome: A Phenomenological Study of Reflective College Experiences

    Science.gov (United States)

    Lee, Kammie Bohlken

    2010-01-01

    This phenomenological study shed light on the reflective college experiences of 11 individuals with Asperger's Syndrome and High Functioning Autism from a competence rather than a deficit model of disability (Biklen, 2005). Using Goleman's model of Social Intelligence (2006) as a theoretical framework, the cognitive, behavioral, and affective…

  8. Punishment and Sympathy Judgments: Is the Quality of Mercy Strained in Asperger's Syndrome?

    Science.gov (United States)

    Channon, Shelley; Fitzpatrick, Sian; Drury, Helena; Taylor, Isabelle; Lagnado, David

    2010-01-01

    This study examined reasoning about wrongdoing in people with Asperger's syndrome (AS) and matched healthy controls in relation to car accident scenarios. The two groups made similar judgments with respect to degree of driver negligence for both fines imposed and sympathy ratings. They also made similar judgments of fines in relation to the type…

  9. Linguistic Characteristics of Individuals with High Functioning Autism and Asperger Syndrome

    Science.gov (United States)

    Seung, Hye Kyeung

    2007-01-01

    This study examined the linguistic characteristics of high functioning individuals with autism and Asperger syndrome. Each group consisted of 10 participants who were matched on sex, chronological age, and intelligence scores. Participants generated a narrative after watching a brief video segment of the Social Attribution Task video. Each…

  10. Can Asperger syndrome be diagnosed at 26 months old? A genetic high-risk single-case study.

    Science.gov (United States)

    Baron-Cohen, Simon; Scott, Fiona; Wheelwright, Sally; Johnson, Mark; Bisarya, Dheraj; Desai, Atman; Ahluwalia, Jag

    2006-04-01

    Asperger syndrome, a heritable condition entailing empathy deficits together with unusually narrow interests in individuals of normal or even above-average intelligence, was recognized only recently. Here we report the first-ever prospective study of a child born to two adults with a formal diagnosis of Asperger syndrome. The child's parents are both scientists (a mathematician and a chemist). The aim of study 1 was to test if the child also developed Asperger syndrome, given the heritability of the condition, and if Asperger syndrome can be detected at 26 months. At 18 months, the child was given the Checklist for Autism in Toddlers, and at 26 months, she was assessed diagnostically for autism spectrum conditions using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observational Scale. The child failed the Checklist for Autism in Toddlers at 18 months and met the criteria for Asperger syndrome at 26 months. This single case is consistent with the hypersystemizing, assortative mating theory of autism. This theory requires further testing with large samples. This study also demonstrates that Asperger syndrome can be diagnosed by age 26 months. The aim of study 2 was to test if dyadic eye contact in infancy is intact in a child later diagnosed with Asperger syndrome. The same child's eye contact was measured at three time points (3, 6, and 9 months) over her first year of life and compared with that of age-matched controls. Although the child had low rates of eye contact at 6 months, it was within the normal range at all three points in the first year of life. We conclude that low levels of eye contact are not predictive of later development of Asperger syndrome. PMID:16900937

  11. Autismo e síndrome de Asperger: uma visão geral Autism and Asperger syndrome: an overview

    Directory of Open Access Journals (Sweden)

    Ami Klin

    2006-05-01

    Full Text Available Autismo e síndrome de Asperger são entidades diagnósticas em uma família de transtornos de neurodesenvolvimento nos quais ocorre uma ruptura nos processos fundamentais de socialização, comunicação e aprendizado. Esses transtornos são coletivamente conhecidos como transtornos invasivos de desenvolvimento. Esse grupo de condições está entre os transtornos de desenvolvimento mais comuns, afetando aproximadamente 1 em cada 200 indivíduos. Eles estão também entre os com maior carga genética entre os transtornos de desenvolvimento, com riscos de recorrência entre familiares da ordem de 2 a 15% se for adotada uma definição mais ampla de critério diagnóstico. Seu início precoce, perfil sintomático e cronicidade envolvem mecanismos biológicos fundamentais relacionados à adaptação social. Avanços em sua compreensão estão conduzindo a uma nova perspectiva da neurociência ao estudar os processos típicos de socialização e das interrupções específicas deles advindas. Esses processos podem levar à emergência de fenótipos altamente heterogêneos associados ao autismo, o paradigmático transtorno invasivo de desenvolvimento e suas variantes. Esta revisão foca o histórico, a nosologia e as características clínicas e associadas aos dois transtornos invasivos de desenvolvimento mais conhecidos - o autismo e a síndrome de Asperger.Autism and Asperger syndrome are diagnostic entities in a family of neurodevelopmental disorders disrupting fundamental processes of socialization, communication and learning, collectively known as pervasive developmental disorders. This group of conditions is among the most common developmental disorders, affecting 1 in every 200 or so individuals. They are also the most strongly genetically related among developmental disorders, with recurrence risks within sibships of the order of 2 to 15% if a broader definition of affectedness is adopted. Their early onset, symptom profile, and chronicity

  12. Face Processing Patterns of Persons with Asperger Syndrome : an Eye Tracking Study

    OpenAIRE

    Bram, Staffan; Lönebrink, Mikael

    2011-01-01

    One of the main diagnostic criteria for Asperger Syndrome is a severe social impairment (American Psychiatric Association [DSM-IV-TR] 2000), something that has often been connected to a more specific impairment in facial recognition. However, the main diagnostic tool (the DSM-IV-TR) has received much criticism during later years and is soon to be revised (Woodbury-Smith & Volkmar 2009). Among other things, many researchers claim that the diagnosis should be complemented with a sliding sca...

  13. Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges

    OpenAIRE

    Mazzone Luigi; Ruta Liliana; Reale Laura

    2012-01-01

    Abstract Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS) and High Functioning Autism (HFA). In this review we examine the interplay between psychiatric comorbidities and AS/HFA. In particular, we will focus our attention on three main issues. First, we examine which psychiatric disorders are more frequently associated with AS/HFA. Second, we review which diagnostic tools are currently available for clinician...

  14. Aspergern, det är jag : En intervjustudie om att leva med Asperger syndrom

    OpenAIRE

    Larsson Abbad, Gunvor

    2007-01-01

    The overall purpose of this interview-study is to increase the knowledge and understanding of persons with Asperger syndrome. For each participant has common and unique aspects been described. The ambition has been to illuminate their perspective of their situation in life and develop the understanding of their quality of life. The participants’ experiences of their diagnosis, and its consequences in their life has been studied. Several aspects of their everyday life have been reported, i.e. ...

  15. Classification, Expertise and the DSM-5 Revision; The Removal of Asperger syndrome

    OpenAIRE

    2012-01-01

    This thesis is an empirical investigation of the fifth edition of the American diagnose manual; Diagnostic and Statistical Manual of Mental Disorders (DSM-5). More specifically it is about the decision to rule out the diagnosis Asperger syndrome (AS), and rather merge it into Autism Spectrum Disorder (ASD). This research aims to explore the controversy surrounding the DSM-5 revision through trending debates about AS, and in comparison to the International Classification of Diseases (ICD). ...

  16. Obsessive–compulsive traits in children and adolescents with Asperger syndrome

    OpenAIRE

    Ruta, Liliana; Mugno, Diego; D’Arrigo, Valentina Genitori; Vitiello, Benedetto; Mazzone, Luigi

    2009-01-01

    Abstract The objective of this study is to examine the occurrence and characteristic features of obsessive?compulsive behaviours in children and adolescents with Asperger syndrome (AS), with respect to a matched obsessive compulsive disorder group (OCD) and a typically developing control group (CG). For this purpose, 60 subjects (20 OCD; 18 AS; 22 CG), aged 8?15 years, matched for age, gender and IQ were compared. AS and OCD patients were diagnosed according to the DSM-IV-TR criter...

  17. Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

    OpenAIRE

    Di Napoli, Agnese; Warrier, Varun; Baron-Cohen, Simon; Chakrabarti, Bhismadev

    2014-01-01

    Background Autism Spectrum Conditions (ASC) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction, alongside unusually repetitive behaviors and narrow interests. ASC are highly heritable and have complex patterns of inheritance where multiple genes are involved, alongside environmental and epigenetic factors. Asperger Syndrome (AS) is a subgroup of these conditions, where there is no history of language or cognitive delay. Animal ...

  18. Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome

    OpenAIRE

    Di Napoli, Agnese; Warrier, Varun; Baron-Cohen, Simon; Chakrabarti, Bhismadev

    2014-01-01

    Background Autism Spectrum Conditions (ASC) are a group of neurodevelopmental conditions characterized by impairments in communication and social interaction, alongside unusually repetitive behaviors and narrow interests. ASC are highly heritable and have complex patterns of inheritance where multiple genes are involved, alongside environmental and epigenetic factors. Asperger Syndrome (AS) is a subgroup of these conditions, where there is no history of language or cognitive delay. Animal mod...

  19. Cortical processing of speech and non-speech sounds in autism and Asperger syndrome

    OpenAIRE

    Lepistö, Tuulia

    2008-01-01

    Autism and Asperger syndrome (AS) are neurodevelopmental disorders characterised by deficient social and communication skills, as well as restricted, repetitive patterns of behaviour. The language development in individuals with autism is significantly delayed and deficient, whereas in individuals with AS, the structural aspects of language develop quite normally. Both groups, however, have semantic-pragmatic language deficits. The present thesis investigated auditory processing in individual...

  20. Oxytocin Promotes Facial Emotion Recognition and Amygdala Reactivity in Adults with Asperger Syndrome

    OpenAIRE

    Domes, Gregor; Kumbier, Ekkehardt; Heinrichs, Markus; Herpertz, Sabine C.

    2013-01-01

    The neuropeptide oxytocin has recently been shown to enhance eye gaze and emotion recognition in healthy men. Here, we report a randomized double-blind, placebo-controlled trial that examined the neural and behavioral effects of a single dose of intranasal oxytocin on emotion recognition in individuals with Asperger syndrome (AS), a clinical condition characterized by impaired eye gaze and facial emotion recognition. Using functional magnetic resonance imaging, we examined whether oxytocin wo...

  1. Social Anxiety in High-Functioning Children and Adolescents with Autism and Asperger Syndrome

    Science.gov (United States)

    Kuusikko, Sanna; Pollock-Wurman, Rachel; Jussila, Katja; Carter, Alice S.; Mattila, Marja-Leena; Ebeling, Hanna; Pauls, David L.; Moilanen, Irma

    2008-01-01

    We examined social anxiety and internalizing symptoms using the Social Phobia and Anxiety Inventory for Children (SPAI-C), the Social Anxiety Scale for Children -Revised (SASC-R), and the Child Behavior Checklist (CBCL) in a sample of fifty-four high-functioning subjects with autism or Asperger syndrome (HFA/AS) (M = 11.2 plus or minus 1.7 years)…

  2. Pragmatic inferences in high-functioning adults with autism and Asperger syndrome

    OpenAIRE

    Pijnacker, J.; Hagoort, P.; Buitelaar, J.; Teunisse, J.; Geurts, B.

    2009-01-01

    Although people with autism spectrum disorders (ASD) often have severe problems with pragmatic aspects of language, little is known about their pragmatic reasoning. We carried out a behavioral study on highfunctioning adults with autistic disorder (n = 11) and Asperger syndrome (n = 17) and matched controls (n = 28) to investigate whether they are capable of deriving scalar implicatures, which are generally considered to be pragmatic inferences. Participants were presented with underinformati...

  3. Abnormal auditory forward masking pattern in the brainstem response of individuals with Asperger syndrome

    OpenAIRE

    Källstrand, Johan; Olsson, Olle; Nehlstedt, Sara Fristedt; Ling, Mia; Nielzén, Sören

    2010-01-01

    Abnormal auditory information processing has been reported in individuals with autism spectrum disorders (ASD). In the present study auditory processing was investigated by recording auditory brainstem responses (ABRs) elicited by forward masking in adults diagnosed with Asperger syndrome (AS). Sixteen AS subjects were included in the forward masking experiment and compared to three control groups consisting of healthy individuals (n = 16), schizophrenic patients (n = 16) and attention defici...

  4. Asperger syndrome in India: Findings from a case-series with respect to clinical profile and comorbidity

    OpenAIRE

    Priya Sreedaran; M V Ashok

    2015-01-01

    Asperger syndrome (AS) is an autism spectrum disorder with a high rate of psychiatric comorbidity. We describe the clinical profile and psychiatric comorbidity in a series of affected individuals referred to an Indian general hospital psychiatry setting. Gilliam Asperger's disorder scale was used to evaluate the clinical characteristics while Mini-International Neuropsychiatric Interview (MINI)-KID and MINI-PLUS were used to assess psychiatric comorbidity. The profile of subjects with AS in o...

  5. "I Just Don't Fit Anywhere": Support Experiences and Future Support Needs of Individuals with Asperger Syndrome in Middle Adulthood

    Science.gov (United States)

    Griffith, Gemma M.; Totsika, Vasiliki; Nash, Susie; Hastings, Richard P.

    2012-01-01

    The experiences of individuals in middle adulthood with Asperger syndrome have been the subject of little previous research, especially in terms of their experience of support services. In the present research, 11 adults with Asperger syndrome were interviewed. Interpretative phenomenological analysis (IPA) was used to interpret the interviews.…

  6. Electrophysiological Signs of Supplementary-Motor-Area Deficits in High-Functioning Autism but Not Asperger Syndrome: An Examination of Internally Cued Movement-Related Potentials

    Science.gov (United States)

    Enticott, Peter G.; Bradshaw, John L.; Iansek, Robert; Tonge, Bruce J.; Rinehart, Nicole J.

    2009-01-01

    Aims: Motor dysfunction is common to both autism and Asperger syndrome, but the underlying neurophysiological impairments are unclear. Neurophysiological examinations of motor dysfunction can provide information about likely sites of functional impairment and can contribute to the debate about whether autism and Asperger syndrome are variants of…

  7. The Perspective of Young Adult Siblings of Individuals with Asperger Syndrome and High Functioning Autism: An Exploration of Grief and Implications for Developmental Transition

    Science.gov (United States)

    Allgood, Nicole R.

    2010-01-01

    Asperger syndrome (AS) and high functioning autism are complex developmental disabilities that have a significant impact on the individual and his/her family. Asperger syndrome is characterized by challenges with understanding non-verbal communication, difficulties with social relationships, and restricted interests. Having a brother or sister…

  8. Cystic fibrosis, common variable immunodeficiency and Aspergers syndrome: an immunological and behavioural challenge.

    LENUS (Irish Health Repository)

    Chotirmall, S H

    2012-02-01

    INTRODUCTION: Cystic fibrosis (CF) is of particular importance in Ireland as the Irish population has both the highest incidence (2.98\\/10,000) and the highest carrier rate (1 in 19) in the world. Primary immunodeficiency has not been previously reported as co-existing with CF. CASE REPORT: We report a unique case of CF associated with a primary immunodeficiency syndrome--common variable immunodeficiency (CVID). DISCUSSION: Our patient has CF, CVID and the additional comorbidity of Aspergers syndrome. The challenges inherent in diagnosing and treating such a case are outlined herein and the successful management of this case is evidenced by the well-preserved lung function of our patient.

  9. Cystic fibrosis, common variable immunodeficiency and Aspergers syndrome: an immunological and behavioural challenge.

    LENUS (Irish Health Repository)

    Chotirmall, S H

    2009-08-07

    INTRODUCTION: Cystic fibrosis (CF) is of particular importance in Ireland as the Irish population has both the highest incidence (2.98\\/10,000) and the highest carrier rate (1 in 19) in the world. Primary immunodeficiency has not been previously reported as co-existing with CF. CASE REPORT: We report a unique case of CF associated with a primary immunodeficiency syndrome-common variable immunodeficiency (CVID). DISCUSSION: Our patient has CF, CVID and the additional comorbidity of Aspergers syndrome. The challenges inherent in diagnosing and treating such a case are outlined herein and the successful management of this case is evidenced by the well-preserved lung function of our patient.

  10. A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis.

    Science.gov (United States)

    Barahona-Corrêa, J B; Filipe, Carlos N

    2015-01-01

    First described in 1944 by Hans Asperger (1944), it was not before 1994 that Asperger Syndrome (AS) was included in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual's fifth edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but also display a rich variety of subtle clinical characteristics that for many distinguish AS from autism. However, difficulties operationalising diagnostic criteria and differentiating AS from autism ultimately led to its merging into the unifying category of Autistic Spectrum Disorders. Here we briefly review the short history of this fascinating condition. PMID:26834663

  11. A Concise History of Asperger Syndrome: the short reign of a troublesome diagnosis

    Directory of Open Access Journals (Sweden)

    Bernardo eBarahona-Correa

    2016-01-01

    Full Text Available First described in 1944 by Hans Asperger, it was not before 1994 that Asperger Syndrome (AS was included in the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual’s 5th edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but also display a rich variety of subtle clinical characteristics that for many distinguish AS from autism. However, difficulties operationalising diagnostic criteria and differentiating AS from autism ultimately led to its merging into the unifying category of Autistic Spectrum Disorders. Here we briefly review the short history of this fascinating condition.

  12. A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis

    Science.gov (United States)

    Barahona-Corrêa, J. B.; Filipe, Carlos N.

    2016-01-01

    First described in 1944 by Hans Asperger (1944), it was not before 1994 that Asperger Syndrome (AS) was included in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual’s fifth edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but also display a rich variety of subtle clinical characteristics that for many distinguish AS from autism. However, difficulties operationalising diagnostic criteria and differentiating AS from autism ultimately led to its merging into the unifying category of Autistic Spectrum Disorders. Here we briefly review the short history of this fascinating condition. PMID:26834663

  13. 阿斯伯格综合征%Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    邹小兵

    2007-01-01

    Asperger syndrome(AS)目前国内尚无统一中文译名:笔者将其译名为阿斯伯格综合征。该征是一种神经系统发育障碍性疾病,特点是社会交往困难,局限、刻板的兴趣和活动模式,常伴有显著的动作笨拙。其症状与儿童孤独症有许多相似之处,但目前对于AS是否属于孤独症的一种一直存在争议。在DSM—Ⅳ中,AS与孤独症分别列为广泛性发育障碍(PDD)的一个亚型。

  14. Avaliação da linguagem oral e escrita em sujeitos com Síndrome de Asperger Language assessment in subjects with Asperger Syndrome

    Directory of Open Access Journals (Sweden)

    Karin Ziliotto Dias

    2009-01-01

    Full Text Available OBJETIVO: avaliar e caracterizar provas fonoaudiológicas de linguagem oral e escrita de sujeitos com Síndrome de Asperger comparativamente a um grupo de sujeitos com desenvolvimento típico. MÉTODOS: avaliou-se 44 sujeitos que constituíram dois grupos: o grupo Asperger, composto por 22 sujeitos diagnosticados por equipe multidisciplinar como portadores de Síndrome de Asperger, conforme os critérios do DSM-IV; e o grupo de comparação, denominado grupo de baixo risco para alterações do desenvolvimento, também com 22 participantes, pareados com os sujeitos do grupo Asperger segundo a idade cronológica. Todos os sujeitos eram do sexo masculino, com idade cronológica entre 10 e 30 anos e quociente intelectual maior ou igual a 68 e foram submetidos à Prova de Consciência Fonológica, Teste de Vocabulário por Imagem Peabody, Prova de Leitura de Palavras e Pseudopalavras, Prova de Compreensão de Leitura, Prova de Escrita sob Ditado de Palavras e Pseudopalavras, Prova de Escrita Semidirigida de Textos. RESULTADOS: a análise estatística revelou diferenças estaticamente significantes entre as medianas da prova de consciência fonológica e entre as médias do teste de vocabulário por imagem Peabody e prova de compreensão de leitura nos dois grupos estudados (pPURPOSE: to evaluate and characterize the oral and written language of subjects with Asperger Syndrome and compare them with a group of subjects with typical development. METHODS: a total of 44 subjects were assessed and divided in two groups. The Asperger group was composed by 22 subjects diagnosed with Asperger Syndrome by an expert clinical team following the DSM-IV criteria. The comparison group, referred to as low risk for developmental disorders was also composed by 22 subjects matched with the subjects in Asperger group by chronological age. All the assessed subjects were right-handed males, with chronological ages between 10 and 30 years and intelligence quotients above

  15. Eshkol–Wachman movement notation in diagnosis: The early detection of Asperger's syndrome

    OpenAIRE

    Teitelbaum, Osnat; Benton, Tom; Shah, Prithvi K; Prince, Andrea; Kelly, Joseph L.; Teitelbaum, Philip

    2004-01-01

    The diagnostic criteria of Asperger's syndrome (AS), considered a part of the autistic spectrum disorder, are still unclear. A critical marker, which distinguishes AS from autism, is the presence of language. The ability of a child with AS to acquire and use language early results in the fact that AS usually is diagnosed much later than autism. Autism is not usually diagnosed until around the age of 3, whereas AS usually is not diagnosed until the child is 6 or 7 years of age. In the present ...

  16. Do adults with high functioning autism or Asperger Syndrome differ in empathy and emotion recognition?

    OpenAIRE

    Montgomery, Charlotte B.; Allison, Carrie; Lai, Meng-Chuan; Cassidy, Sarah; Langdon, Peter E; Baron-Cohen, Simon

    2016-01-01

    The present study examined whether adults with high functioning autism (HFA) showed greater difficulties in (1) their self-reported ability to empathise with others and/or (2) their ability to read mental states in others’ eyes than adults with Asperger syndrome (AS). The Empathy Quotient (EQ) and ‘Reading the Mind in the Eyes’ Test (Eyes Test) were compared in 43 adults with AS and 43 adults with HFA. No significant difference was observed on EQ score between groups, while adults with AS per...

  17. Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome

    OpenAIRE

    Scroggins, Michaela L; Lyn G Litchke; Ting Liu

    2016-01-01

    This case focused on a 7-year-old boy with Apert and Asperger's syndrome who attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp. Results from the pre- and post-tests on Treatment and Research Institute for Autism Social Skills Assessment showed improvements in the total score changes from 19 to 7 for disruptive behaviors. Sparks Target Behavior Checklist scores changed from eight to one showing progression in ability to stay on task. Yoga Pose Rating Scale display...

  18. Autism, Asperger's syndrome and semantic-pragmatic disorder: where are the boundaries?

    Science.gov (United States)

    Bishop, D V

    1989-08-01

    The diagnostic criteria for autism have been refined and made more objective since Kanner first described the syndrome, so there is now reasonable consistency in how this diagnosis is applied. However, many children do not meet these criteria, yet show some of the features of autism. Where language development is impaired, such children tend to be classed as cases of developmental dysphasia (or specific language impairment) whereas those who learn to talk at the normal age may be diagnosed as having Asperger's syndrome. It is argued that rather than thinking in terms of rigid diagnostic categories, we should recognise that the core syndrome of autism shades into other milder forms of disorder in which language or non-verbal behaviour may be disproportionately impaired. PMID:2690915

  19. Asperger syndrome in a boy with a balanced de novo translocation: t(17;19)(p13.3;p11)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-10

    The cause of Asperger syndrome is unknown. It is classified as a form of childhood autism. Familial aggregation in infantile autism has been reported. Asperger syndrome has also been considered as being genetically transmitted and certain of its characteristics have tended to occur in other relatives, especially in the fathers. We describe a 10-year-old boy with a clinical diagnosis of Asperger syndrome and a balanced de novo translocation (t(17;19)9p13.3;p11). His parents are not consanguineous and are healthy, as are his three brothers. 5 refs.

  20. Success of behaviour modification in a child with Asperger's syndrome

    OpenAIRE

    Šteh, Urška

    2012-01-01

    The topic of this degree dissertation is the success rate of behaviour modification in a child with the autistic spectrum disorder Asperger’s syndrome. I decided to pursue this subject based on my work in a kindergarten, where I became acquainted with a boy with Asperger’s syndrome. The issue I encountered was that I could find no sources where the method of behaviour modification was implemented with persons that have Asperger’s syndrome. For this reason I decided to determine, by using...

  1. Síndrome de Asperger e TOC: comorbidade ou unidade? Asperger syndrome and OCD: comorbidity or unity?

    OpenAIRE

    José Maria Aranha Fonseca; Ana Luiza Morais Campos; José Ramón Rodriguez Arras López

    2007-01-01

    Comportamentos repetitivos, estereotipias e interesses restritos são alguns dos principais sintomas que compõem o transtorno de Asperger. Todavia, até que ponto é possível diferenciá-los de sintomas obsessivo-compulsivos que preencham critérios para transtorno obsessivo-compulsivo (TOC)? Muitas vezes, não é possível. Este trabalho relata o caso de um paciente com síndrome de Asperger e TOC. Abordamos até que ponto é realmente importante a distinção de um TOC como comorbidade distinta do Asper...

  2. The Asperger Syndrome (and High-Functioning Autism) Diagnostic Interview (ASDI): A Preliminary Study of a New Structured Clinical Interview.

    Science.gov (United States)

    Gillberg, Christopher; Gillberg, Carina; Rastam, Maria; Wentz, Elisabeth

    2001-01-01

    The development of the Asperger Syndrome (and high-functioning autism) Diagnostic Interview (ASDI) is described. Preliminary data from a clinical study of 20 individuals (ages 6-55) suggest that interrater reliability and test-retest stability may be excellent, with kappas exceeding 0.90 in both instances. The validity appears to be relatively…

  3. Can a Diagnosis of Asperger Syndrome Be Made in Very Young Children with Suspected Autism Spectrum Disorder?

    Science.gov (United States)

    McConachie, Helen; Le Couteur, Ann; Honey, Emma

    2005-01-01

    Of a cohort of 104 children with Autism, PDD-NOS or specific language disorder, recruited at age 2-3 years of age, only three appeared to meet diagnostic assessment criteria for Asperger syndrome (AS). The children were followed up at 4-5 years, and assessments at both time points included the Autism Diagnostic Interview (ADI-R), the Autism…

  4. Emotion Perception in Asperger's Syndrome and High-Functioning Autism: The Importance of Diagnostic Criteria and Cue Intensity

    Science.gov (United States)

    Mazefsky, Carla A.; Oswald, Donald P.

    2007-01-01

    This study compared emotion perception accuracy between children with Asperger's syndrome (AS) and high-functioning autism (HFA). Thirty children were diagnosed with AS or HFA based on empirically supported diagnostic criteria and administered an emotion perception test consisting of facial expressions and tone of voice cues that varied in…

  5. Asperger Syndrome and Autism: A Comparative Longitudinal Follow-Up Study More than 5 Years after Original Diagnosis

    Science.gov (United States)

    Cederlund, Mats; Hagberg, Bibbi; Billstedt, Eva; Gillberg, I. Carina; Gillberg, Christopher

    2008-01-01

    Prospective follow-up study of 70 males with Asperger syndrome (AS), and 70 males with autism more than 5 years after original diagnosis. Instruments used at follow-up included overall clinical assessment, the Diagnostic Interview for Social and Communication Disorders, Wechsler Intelligence Scales, Vineland Adaptive Behavior Scales, and Global…

  6. Asperger's Syndrome: A Comparison of Clinical Diagnoses and Those Made According to the ICD-10 and DSM-IV

    Science.gov (United States)

    Woodbury-Smith, Marc; Klin, Ami; Volkmar, Fred

    2005-01-01

    The diagnostic criteria for Asperger Syndrome (AS) according to ICD-10 and DSM-IV have been criticized as being too narrow in view of the rules of onset and precedence, whereby autism takes precedence over AS in a diagnostic hierarchy. In order to investigate this further, cases from the DSM-IV multicenter study who had been diagnosed clinically…

  7. Brief Report: Impaired Differentiation of Vegetative/Affective and Intentional Nonverbal Vocalizations in a Subject with Asperger Syndrome (AS)

    Science.gov (United States)

    Dietrich, Susanne; Hertrich, Ingo; Riedel, Andreas; Ackermann, Hermann

    2012-01-01

    The Asperger syndrome (AS) includes impaired recognition of other people's mental states. Since language-based diagnostic procedures may be confounded by cognitive-linguistic compensation strategies, nonverbal test materials were created, including human affective and vegetative sounds. Depending on video context, each sound could be interpreted…

  8. Perception of Social Relationships with Classmates and Social Support in Adolescents with Asperger Syndrome Attending Mainstream Schools in Poland

    Science.gov (United States)

    Pisula, Ewa; Lukowska, Ewa

    2012-01-01

    One of the factors affecting successful inclusion of adolescents with Asperger syndrome (AS) in mainstream schools is positive relationships with classmates. The present study investigates how adolescents with AS: (1) perceive their classmates' attitude towards them; (2) what attitude towards classmates they declare; and (3) how they assess the…

  9. The Importance of the Eye Area in Face Identification Abilities and Visual Search Strategies in Persons with Asperger Syndrome

    Science.gov (United States)

    Falkmer, Marita; Larsson, Matilda; Bjallmark, Anna; Falkmer, Torbjorn

    2010-01-01

    Partly claimed to explain social difficulties observed in people with Asperger syndrome, face identification and visual search strategies become important. Previous research findings are, however, disparate. In order to explore face identification abilities and visual search strategies, with special focus on the importance of the eye area, 24…

  10. Epilepsy in Individuals with a History of Asperger's Syndrome: A Danish Nationwide Register-Based Cohort Study

    Science.gov (United States)

    Mouridsen, Svend Erik; Rich, Bente; Isager, Torben

    2013-01-01

    We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger's syndrome on February 7, 2011. All 4,180 identified cases with AS (3,431 males and 749 females) were screened through the…

  11. Self- Versus Teacher Management of Behavior for Elementary School Students with Asperger Syndrome: Impact on Classroom Behavior

    Science.gov (United States)

    Shogren, Karrie A.; Lang, Russell; Machalicek, Wendy; Rispoli, Mandy J.; O'Reilly, Mark

    2011-01-01

    The purpose of this study was to evaluate and compare the effectiveness of a token economy and a self-management intervention in an inclusive kindergarten classroom. Two 5-year-old children with Asperger syndrome who were struggling to follow classroom rules participated in the study. An ABACABAC (A = baseline, B = token economy, C =…

  12. Supporting Self-Regulated Learning for College Students with Asperger Syndrome: Exploring the "Strategies for College Learning" Model

    Science.gov (United States)

    Ness, Bryan M.

    2013-01-01

    In this study, I piloted the feasibility, effects, and perceived acceptability of a peer mentoring intervention targeting academic achievement and self-regulated learning (SRL) for three college students with Asperger syndrome. The approach, dubbed Strategies for College Learning (SCL), features individualized assessment of academic performance in…

  13. Parent Perceptions of the Anticipated Needs and Expectations for Support for Their College-Bound Students with Asperger's Syndrome

    Science.gov (United States)

    Morrison, Julie Q.; Sansosti, Frank J.; Hadley, Wanda M.

    2009-01-01

    Many students with Asperger's Syndrome have the cognitive ability and specific interests to be successful academically at the college level. However, these students often have difficulties navigating social systems, and higher education presents great challenges. The purpose of this study was to explore parent perceptions regarding the: (a)…

  14. Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years after Initial Diagnosis

    Science.gov (United States)

    Gillberg, I. Carina; Helles, Adam; Billstedt, Eva; Gillberg, Christopher

    2016-01-01

    We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13-26 years). Only three of the 50 men had "never" met criteria for an additional psychiatric/neurodevelopmental diagnosis and…

  15. Inhibition of Return in Response to Eye Gaze and Peripheral Cues in Young People with Asperger's Syndrome

    Science.gov (United States)

    Marotta, Andrea; Pasini, Augusto; Ruggiero, Sabrina; Maccari, Lisa; Rosa, Caterina; Lupianez, Juan; Casagrande, Maria

    2013-01-01

    Inhibition of return (IOR) reflects slower reaction times to stimuli presented in previously attended locations. In this study, we examined this inhibitory after-effect using two different cue types, eye-gaze and standard peripheral cues, in individuals with Asperger's syndrome and typically developing individuals. Typically developing…

  16. The Construction and Evaluation of Three Measures of Affectionate Behaviour for Children with Asperger's Syndrome

    Science.gov (United States)

    Sofronoff, Kate; Lee, Jessica; Sheffield, Jeanie; Attwood, Tony

    2014-01-01

    Children with Asperger's syndrome are often reported by their parents as having difficulties communicating affection. This study aimed to develop a valid measure of affectionate behaviour that could be used to investigate and quantify these anecdotal reports and then be used in further intervention research. Using parent and expert focus…

  17. An Exploration of Support Factors Available to Higher Education Students with High Functioning Autism or Asperger Syndrome

    Science.gov (United States)

    Rutherford, Emily N.

    2013-01-01

    This qualitative phenomenological research study used narrative inquiry to explore the support factors available to students with High Functioning Autism or Asperger Syndrome in higher education that contribute to their success as perceived by the students. Creswell's (2009) six step method for analyzing phenomenological studies was used to…

  18. Multirater Congruence on the Social Skills Assessment of Children with Asperger Syndrome: Self, Mother, Father, and Teacher Ratings

    Science.gov (United States)

    Kalyva, Efrosini

    2010-01-01

    Children with Asperger Syndrome (AS) who attend mainstream settings face social skills deficits that have not been adequately explored. This study aims to examine social skills through self-reports of children with AS (N = 21) and a matched group of typically developing peers, as well as reports from their mothers, fathers, and teachers. Results…

  19. The Effectiveness of Social Skills Intervention Targeting Nonverbal Communication for Adolescents with Asperger Syndrome and Related Pervasive Developmental Delays.

    Science.gov (United States)

    Barnhill, Gena P.; Cook, Katherine Tapscott; Tebbenkamp, Kelly; Myles, Brenda Smith

    2002-01-01

    A study investigated the effectiveness of an 8-week social skills intervention targeting nonverbal communication for eight adolescents with Asperger syndrome. Although minimal nonverbal communication skills development was apparent, some social relationships were developed and the ability of some participants to read the nonverbal communication of…

  20. Social communication impairments in children and adolescents with Asperger syndrome: Slow response time and the impact of prompting

    DEFF Research Database (Denmark)

    Kaland, Nils; Mortensen, Erik Lykke; Smith, Lars

    2011-01-01

    In the present study children and adolescents with Asperger syndrome (N = 13) and a matched control group of typically developing children and adolescents were presented with 26 vignettes of daily life situations, including irony, metaphors, contrary emotions, jealousy, social blunders, and...

  1. A 380-kb Duplication in 7p22.3 Encompassing the LFNG Gene in a Boy with Asperger Syndrome

    NARCIS (Netherlands)

    Vulto-van Silfhout, A.T.; Brouwer, A.F. de; Leeuw, N. de; Obihara, C.C.; Brunner, H.G.; Vries, B.B. de

    2012-01-01

    De novo genomic aberrations are considered an important cause of autism spectrum disorders. We describe a de novo 380-kb gain in band p22.3 of chromosome 7 in a patient with Asperger syndrome. This duplicated region contains 9 genes including the LNFG gene that is an important regulator of NOTCH sig

  2. Oral Language Impairments in Developmental Disorders Characterized by Language Strengths: A Comparison of Asperger Syndrome and Nonverbal Learning Disabilities

    Science.gov (United States)

    Stothers, M. E.; Cardy, J. Oram

    2012-01-01

    Asperger syndrome (AS) and nonverbal learning disabilities (NLD) are developmental disorders in which linguistic ability is reported to be stronger than in disorders from which they must be distinguished for diagnosis. Children and adults with AS and NLD share pragmatic weaknesses, atypical social behaviours, and some cognitive features. To date,…

  3. Evidence for Impaired Verbal Identification but Intact Nonverbal Recognition of Fearful Body Postures in Asperger's Syndrome

    Science.gov (United States)

    Doody, John P.; Bull, Peter

    2013-01-01

    While most studies of emotion recognition in Asperger's Syndrome (AS) have focused solely on the verbal decoding of affective states, the current research employed the novel technique of using both nonverbal matching and verbal labeling tasks to examine the decoding of emotional body postures and facial expressions. AS participants performed…

  4. Cognitive Behavior Therapy for Social Anxiety Disorder in the Context of Asperger's Syndrome: A Single-Subject Report

    Science.gov (United States)

    Cardaciotto, LeeAnn; Herbert, James D.

    2004-01-01

    Asperger's Syndrome (AS) is a developmental disorder characterized by social impairment, highly circumscribed interests, repetitive behaviors, and motor clumsiness. The social impairment features of AS are similar to characteristics of social anxiety disorder (SAD). However, little is known about the comorbidity of these disorders or the treatment…

  5. From Tarantulas to Toilet Brushes: Understanding the Special Interest Areas of Children and Youth With Asperger Syndrome

    Science.gov (United States)

    Winter-Messiers, Mary Ann

    2007-01-01

    The purpose of this exploratory study was to evaluate the impact of special interest areas on children and youth with Asperger syndrome (AS) and their families. The research team conducted interviews about special interests with 2 girls and 21 boys with AS, ages 7 to 21, who were eligible for services under autism and enrolled in an extended…

  6. Universal Design: A Tool to Help College Students with Asperger's Syndrome Engage on Campus

    Science.gov (United States)

    Taylor, Colette M.; Colvin, Kathryn L.

    2013-01-01

    Transitioning from high school to college is challenging for many students, but for none more so than students with Asperger's syndrome. Colette M. Taylor and Kathryn L. Colvin introduce the concept of universal design as an effective approach to supporting this increasing subpopulation of students.

  7. Anxiety and Depression Symptoms in Children with Asperger Syndrome Compared with Attention-Deficit/Hyperactivity Disorder and Depressive Disorder

    Science.gov (United States)

    Park, Subin; Park, Min-Hyeon; Kim, Hyo Jin; Yoo, Hee Jeong

    2013-01-01

    The objective of this study was to examine (a) anxiety and depression symptoms in children with Asperger syndrome (AS) compared to children with attention-deficit/hyperactivity disorder (ADHD) and children with depressive disorder; (b) parental anxiety and depressive symptoms in the three groups; and (c) the association between the anxiety and…

  8. Mastering Social and Organization Goals: Strategy Use by Two Children with Asperger Syndrome during Cognitive Orientation to Daily Occupational Performance

    Science.gov (United States)

    Rodger, Sylvia; Vishram, Alysha

    2010-01-01

    Preliminary data supports the effectiveness of Cognitive Orientation to (daily) Occupational Performance (CO-OP) for children with Asperger syndrome (AS). Children with AS often experience social and organizational difficulties spanning daily occupations. This case study explored the pattern of Global Strategies and Domain-Specific Strategies…

  9. Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome

    OpenAIRE

    Roine, Ulrika; Salmi, Juha; Roine, Timo; Wendt, Taina Nieminen-von; LeppÀmÀki, Sami; Rintahaka, Pertti; Tani, Pekka; Leemans, Alexander; Sams, Mikko

    2015-01-01

    Abstract Background The aim of this study was to investigate potential differences in neural structure in individuals with Asperger syndrome (AS), high-functioning individuals with autism spectrum disorder (ASD). The main symptoms of AS are severe impairments in social interactions and restricted or repetitive patterns of behaviors, interests or activities. Methods ...

  10. Abnormal auditory forward masking pattern in the brainstem response of individuals with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Johan Källstrand

    2010-05-01

    Full Text Available Johan Källstrand1, Olle Olsson2, Sara Fristedt Nehlstedt1, Mia Ling Sköld1, Sören Nielzén21SensoDetect AB, Lund, Sweden; 2Department of Clinical Neuroscience, Section of Psychiatry, Lund University, Lund, SwedenAbstract: Abnormal auditory information processing has been reported in individuals with autism spectrum disorders (ASD. In the present study auditory processing was investigated by recording auditory brainstem responses (ABRs elicited by forward masking in adults diagnosed with Asperger syndrome (AS. Sixteen AS subjects were included in the forward masking experiment and compared to three control groups consisting of healthy individuals (n = 16, schizophrenic patients (n = 16 and attention deficit hyperactivity disorder patients (n = 16, respectively, of matching age and gender. The results showed that the AS subjects exhibited abnormally low activity in the early part of their ABRs that distinctly separated them from the three control groups. Specifically, wave III amplitudes were significantly lower in the AS group than for all the control groups in the forward masking condition (P < 0.005, which was not the case in the baseline condition. Thus, electrophysiological measurements of ABRs to complex sound stimuli (eg, forward masking may lead to a better understanding of the underlying neurophysiology of AS. Future studies may further point to specific ABR characteristics in AS individuals that separate them from individuals diagnosed with other neurodevelopmental diseases.Keywords: asperger syndrome, auditory brainstem response, forward masking, psychoacoustics

  11. Photoanthropometric Study of Dysmorphic Features of the Face in Children with Autism and Asperger Syndrome

    Directory of Open Access Journals (Sweden)

    Katarzyna Ziora

    2012-04-01

    Full Text Available Objective: Childhood autism is a neurodevelopmental disorder characterized by impairments in social interactions, verbal and non-verbal communication and by a pattern of stereotypical behaviors and interests. The aim of this study was to estimate the dysmorphic facial features of children with autism and children with Asperger syndrome . Methods: The examination was conducted on 60 children (30 with childhood autism and 30 with Asperger syndrome. The photo anthropometric method used in this study followed the protocol established by Stengel-Rutkowski et al . Results: The performed statistical analysis showed that in patients with childhood autism, the anteriorly rotated ears and the long back of the nose appeared more often. In the group of children with autism, there was a connection between the amount of dysmorphies and the presence of some somatic diseases in the first-degree relatives. There was also a connection between the motor coordination and the age the child began to walk. Discussion: In patients with childhood autism, there were certain dysmorphies (like the anterior rotated ears and the long back of the nose which appeared more often. Although the connection was not statistically significant, it seemed to concur with data from the literature . Conclusion: Formulation of the other conclusions would require broader studies e.g. dealing with a familial analysis of dysmorphic features.

  12. Asperger syndrome in India: findings from a case-series with respect to clinical profile and comorbidity.

    Science.gov (United States)

    Sreedaran, Priya; Ashok, M V

    2015-01-01

    Asperger syndrome (AS) is an autism spectrum disorder with a high rate of psychiatric comorbidity. We describe the clinical profile and psychiatric comorbidity in a series of affected individuals referred to an Indian general hospital psychiatry setting. Gilliam Asperger's disorder scale was used to evaluate the clinical characteristics while Mini-International Neuropsychiatric Interview (MINI)-KID and MINI-PLUS were used to assess psychiatric comorbidity. The profile of subjects with AS in our case-series appears similar to that published elsewhere with high rates of psychiatric comorbidity. Mental health professionals should evaluate for psychiatric comorbidity in individuals with autism spectrum disorders. PMID:25969609

  13. Non linear analyses of speech and prosody in Asperger's syndrome

    OpenAIRE

    Fusaroli, Riccardo; Bang, Dan; Weed, Ethan

    2013-01-01

    It is widely acknowledged that people on the ASD spectrum behave atypically in the way they modulate aspects of speech and voice, including pitch, fluency, and voice quality. ASD speech has been described at times as “odd”, “mechanical”, or “monotone”. However, it has proven difficult to quantify and explain this oddness of speech pattern. In this project, we quantify how the speech patterns of people with Asperger’s Syndrome (AS) differ from that of matched controls. To do so, we employed bo...

  14. Non linear analyses of speech and prosody in Asperger's syndrome

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Bang, Dan; Weed, Ethan

    It is widely acknowledged that people on the ASD spectrum behave atypically in the way they modulate aspects of speech and voice, including pitch, fluency, and voice quality. ASD speech has been described at times as “odd”, “mechanical”, or “monotone”. However, it has proven difficult to quantify...... the results in a supervised machine-learning process to classify speech production as either belonging to the control or the AS group as well as to assess the severity of the disorder (as measured by Autism Spectrum Quotient), based solely on acoustic features.......It is widely acknowledged that people on the ASD spectrum behave atypically in the way they modulate aspects of speech and voice, including pitch, fluency, and voice quality. ASD speech has been described at times as “odd”, “mechanical”, or “monotone”. However, it has proven difficult to quantify...... and explain this oddness of speech pattern. In this project, we quantify how the speech patterns of people with Asperger’s Syndrome (AS) differ from that of matched controls. To do so, we employed both traditional measures (pitch range and standard deviation, pause duration, and so on) and 2) non...

  15. Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges

    Directory of Open Access Journals (Sweden)

    Mazzone Luigi

    2012-06-01

    Full Text Available Abstract Several psychiatric conditions, both internalizing and externalizing, have been documented in comorbidity with Asperger Syndrome (AS and High Functioning Autism (HFA. In this review we examine the interplay between psychiatric comorbidities and AS/HFA. In particular, we will focus our attention on three main issues. First, we examine which psychiatric disorders are more frequently associated with AS/HFA. Second, we review which diagnostic tools are currently available for clinicians to investigate and diagnose the associated psychiatric disorders in individuals with AS/HFA. Third, we discuss the challenges that clinicians and researchers face in trying to determine whether the psychiatric symptoms are phenotypic manifestations of AS/HFA or rather they are the expression of a distinct, though comorbid, disorder. We will also consider the role played by the environment in the manifestation and interpretation of these symptoms. Finally, we will propose some strategies to try to address these issues, and we will discuss therapeutic implications.

  16. Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome

    Science.gov (United States)

    Scroggins, Michaela L; Litchke, Lyn G; Liu, Ting

    2016-01-01

    This case focused on a 7-year-old boy with Apert and Asperger's syndrome who attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp. Results from the pre- and post-tests on Treatment and Research Institute for Autism Social Skills Assessment showed improvements in the total score changes from 19 to 7 for disruptive behaviors. Sparks Target Behavior Checklist scores changed from eight to one showing progression in ability to stay on task. Yoga Pose Rating Scale displayed the transformation in total scores from 80 = emerging to 115 = consistency in pose performance. The field notes revealed the positive development in expressive emotions, social engagement, and decline in looking around. Outside class parent and school behavioral specialist reported the improved ability to self-regulate stress using lion's breath and super brain. These findings indicate an improvement in behaviors that influenced the physical performance, emotional expression, and social interaction after yoga training for this child. PMID:26865777

  17. Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome.

    Science.gov (United States)

    Scroggins, Michaela L; Litchke, Lyn G; Liu, Ting

    2016-01-01

    This case focused on a 7-year-old boy with Apert and Asperger's syndrome who attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp. Results from the pre- and post-tests on Treatment and Research Institute for Autism Social Skills Assessment showed improvements in the total score changes from 19 to 7 for disruptive behaviors. Sparks Target Behavior Checklist scores changed from eight to one showing progression in ability to stay on task. Yoga Pose Rating Scale displayed the transformation in total scores from 80 = emerging to 115 = consistency in pose performance. The field notes revealed the positive development in expressive emotions, social engagement, and decline in looking around. Outside class parent and school behavioral specialist reported the improved ability to self-regulate stress using lion's breath and super brain. These findings indicate an improvement in behaviors that influenced the physical performance, emotional expression, and social interaction after yoga training for this child. PMID:26865777

  18. Increasing the Understanding and Demonstration of Appropriate Affection in Children with Asperger Syndrome: A Pilot Trial

    Directory of Open Access Journals (Sweden)

    Kate Sofronoff

    2011-01-01

    Full Text Available The study was conducted to examine relationships between affectionate behavior in children with Asperger syndrome and variables likely to influence its expression (e.g., tactile sensitivity, social ability. It also evaluated the impact of a cognitive behavioral intervention that aimed to improve a child's understanding and expression of affection. Twenty-one children, aged 7 to 12 years, participated in the trial. The results showed significant correlations between measures of affection and tactile sensitivity and social ability. After attending the 5-week program, parents identified significant increases in the appropriateness of children's affectionate behavior both towards immediate family and people outside the immediate family, despite reporting no significant changes in their child's general difficulties with affectionate behavior. There was a significant improvement in children's understanding of the purpose of affection. The findings are discussed as well as the limitations of the study.

  19. Do Adults with High Functioning Autism or Asperger Syndrome Differ in Empathy and Emotion Recognition?

    Science.gov (United States)

    Montgomery, Charlotte B; Allison, Carrie; Lai, Meng-Chuan; Cassidy, Sarah; Langdon, Peter E; Baron-Cohen, Simon

    2016-06-01

    The present study examined whether adults with high functioning autism (HFA) showed greater difficulties in (1) their self-reported ability to empathise with others and/or (2) their ability to read mental states in others' eyes than adults with Asperger syndrome (AS). The Empathy Quotient (EQ) and 'Reading the Mind in the Eyes' Test (Eyes Test) were compared in 43 adults with AS and 43 adults with HFA. No significant difference was observed on EQ score between groups, while adults with AS performed significantly better on the Eyes Test than those with HFA. This suggests that adults with HFA may need more support, particularly in mentalizing and complex emotion recognition, and raises questions about the existence of subgroups within autism spectrum conditions. PMID:26883645

  20. Boys with Asperger Syndrome Grow Up: Psychiatric and Neurodevelopmental Disorders 20 Years After Initial Diagnosis.

    Science.gov (United States)

    Gillberg, I Carina; Helles, Adam; Billstedt, Eva; Gillberg, Christopher

    2016-01-01

    We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13-26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS. PMID:26210519

  1. Creating a Positive Elementary Environment for Asperger Children

    Science.gov (United States)

    Batesko, Mary Lee

    2007-01-01

    Asperger's Syndrome is a neurological based disorder that primarily affects a person's ability to be successful with social relationships. Asperger's Disorder or Asperger's Syndrome is defined by the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (2000) as, "The essential features of Asperger's Disorder are severe and…

  2. Autismo e síndrome de Asperger: uma visão geral Autism and Asperger syndrome: an overview

    OpenAIRE

    Ami Klin

    2006-01-01

    Autismo e síndrome de Asperger são entidades diagnósticas em uma família de transtornos de neurodesenvolvimento nos quais ocorre uma ruptura nos processos fundamentais de socialização, comunicação e aprendizado. Esses transtornos são coletivamente conhecidos como transtornos invasivos de desenvolvimento. Esse grupo de condições está entre os transtornos de desenvolvimento mais comuns, afetando aproximadamente 1 em cada 200 indivíduos. Eles estão também entre os com maior carga genética entre ...

  3. Der Lebenslauf von Menschen mit Asperger Syndrom / High-Functioning Autismus : eine Interviewstudie mit Schwerpunkt auf dem Erwachsenenalter

    OpenAIRE

    Gomolla, Annette

    2002-01-01

    Über den Lebensverlauf und insbesondere das Erwachsenenalter von Menschen mit Asperger Syndrom (AS) / High-Functioning Autismus (HFA) ist bisher wenig bekannt, insbesondere gibt es keine Studien, die die Erfahrungen und Bewertungen der Personen selbst in den Mittelpunkt stellen. Die vorliegende Studie hat sich bemüht, bestehende Informationen und Einschätzungen Dritter über Kindheit, Jugendzeit und Erwachsenenalter mit den subjektiven Sichtweisen dieser Personengruppe zu vergleichen und spezi...

  4. The components required to build a therapeutic relationship with children diagnosed with Asperger Syndrome / cEdré Gerber.

    OpenAIRE

    Gerber, Edré

    2013-01-01

    The aim of this study was to explore and describe the components required to build a therapeutic relationship with children diagnosed with Asperger Syndrome. Through this study therapists and other professionals working with these children could be guided to form functioning and healthy therapeutic relationships with children diagnosed with AS. An inductive, qualitative method was used to gain insight into the components required to build a therapeutic relationship with children diagnosed...

  5. A descriptive social and health profile of a community sample of adults and adolescents with Asperger syndrome

    OpenAIRE

    Tantam Digby; Balfe Myles

    2010-01-01

    Abstract Background Little is known about the health and social profile of adolescents and adults with Asperger syndrome (AS) living in the community. We conducted a study to describe the living, employment and psycho-social situation of a community sample of forty two adults and adolescents with AS, and to describe these indivdiuals' experiences of accessing health services and taking medication. Findings Most respondents (including those over eighteen years of age) lived at home with their ...

  6. The relationship between theory of mind and autobiographical memory in high-functioning autism and Asperger syndrome.

    Science.gov (United States)

    Adler, Noga; Nadler, Benny; Eviatar, Zohar; Shamay-Tsoory, Simone G

    2010-06-30

    The relationship between theory of mind (ToM) and autobiographical memory (AM) in high-functioning autism (HFA) and Asperger syndrome (AS) has never been investigated. Here, we show that ToM abilities could be predicted by levels of AM in HFA and AS as compared to controls, suggesting that difficulties in AM are closely related to ToM impairments in HFA and AS. PMID:20452047

  7. Asperger's in the Holmes family.

    Science.gov (United States)

    Altschuler, Eric L

    2013-09-01

    I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock. PMID:23381486

  8. Integrating intention and context: assessing social cognition in adults with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Sandra Baez

    2012-11-01

    Full Text Available Deficits in social cognition are an evident clinical feature of the Asperger syndrome (AS. Although many daily life problems of adults with AS are related to social cognition impairments, few studies have conducted comprehensive research in this area. The current study examined multiple domains of social cognition in adults with AS assessing the executive functions (EF and exploring the intra and inter-individual variability. Fifteen adults diagnosed with AS and 15 matched healthy controls completed a battery of social cognition tasks. This battery included measures of emotion recognition, theory of mind, empathy, moral judgment, social norms knowledge and self-monitoring behavior in social settings. We controlled for the effect of EF and explored the individual variability. The results indicated that adults with AS had a fundamental deficit in several domains of social cognition. We also found high variability in the social cognition tasks. In these tasks, AS participants obtained mostly subnormal performance. Executive functions did not seem to play a major role in the social cognition impairments. Our results suggest that adults with AS present a pattern of social cognition deficits characterized by the decreased ability to implicitly encode and integrate contextual information in order to access to the social meaning. Nevertheless, when social information is explicitly presented or the situation can be navigated with abstract rules, performance is improved. Our findings have implications for the diagnosis and treatment of individuals with AS as well as for the neurocognitive models of this syndrome.

  9. The neuropsychology of male adults with high-functioning autism or asperger syndrome.

    Science.gov (United States)

    Wilson, C Ellie; Happé, Francesca; Wheelwright, Sally J; Ecker, Christine; Lombardo, Michael V; Johnston, Patrick; Daly, Eileen; Murphy, Clodagh M; Spain, Debbie; Lai, Meng-Chuan; Chakrabarti, Bhismadev; Sauter, Disa A; Baron-Cohen, Simon; Murphy, Declan G M

    2014-10-01

    Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, half with ASD and half without, completed tasks assessing IQ, a broad range of cognitive skills, and autistic and comorbid symptomatology. The aims of the study were, first, to determine whether significant differences existed between cases and controls on cognitive tasks, and whether cognitive profiles, derived using a multivariate classification method with data from multiple cognitive tasks, could distinguish between the two groups. Second, to establish whether cognitive skill level was correlated with degree of autistic symptom severity, and third, whether cognitive skill level was correlated with degree of comorbid psychopathology. Fourth, cognitive characteristics of individuals with Asperger Syndrome (AS) and high-functioning autism (HFA) were compared. After controlling for IQ, ASD and control groups scored significantly differently on tasks of social cognition, motor performance, and executive function (P's diagnostic process when used in conjunction with other data sources-including clinical history. PMID:24903974

  10. Narrative competence and internal state language of children with Asperger Syndrome and ADHD.

    Science.gov (United States)

    Rumpf, Anna-Lena; Kamp-Becker, Inge; Becker, Katja; Kauschke, Christina

    2012-01-01

    The central question of the present study was whether there are differences between children with Asperger Syndrome (AS), children with attention deficit hyperactivity disorder (ADHD) and healthy controls (HC) with respect to the organization of narratives and their verbalization of internal states. Oral narrations of a wordless picture book produced by 31 children (11 with AS, 9 with ADHD, 11 HC, aged 8-12) were analyzed regarding the following linguistic variables: story length, sentence structure and sentence complexity, coherence and cohesion of the stories, verbalization of the narrator's perspective, as well as internal state language (verbal reference to mental states). Considerable similarities were noted between the two clinical groups, which deviate from HC children. Narratives of the children with AS and ADHD were shorter than the narratives produced by the HC children. The children of both clinical groups failed to point out the main aspects of the story. In particular, children with AS did not refer to cognitive states as often as the other groups. With respect to narrative coherence, they produced fewer pronominal references than HC children and children with ADHD. In conclusion, the two clinical groups differed from the HC group on a number of features, and a less frequent reference to cognitive states was identified for the children with AS. PMID:22522198

  11. Neuroanatomical Markers of Neurological Soft Signs in Recent-Onset Schizophrenia and Asperger-Syndrome.

    Science.gov (United States)

    Hirjak, Dusan; Wolf, Robert C; Paternoga, Isa; Kubera, Katharina M; Thomann, Anne K; Stieltjes, Bram; Maier-Hein, Klaus H; Thomann, Philipp A

    2016-05-01

    Neurological soft signs (NSS) are frequently found in psychiatric disorders of significant neurodevelopmental origin. Previous MRI studies in schizophrenia have shown that NSS are associated with abnormal cortical, thalamic and cerebellar structure and function. So far, however, no neuroimaging studies investigated brain correlates of NSS in individuals with Asperger-Syndrome (AS) and the question whether the two disorders exhibit common or disease-specific cortical correlates of NSS remains unresolved. High-resolution MRI data at 3 T were obtained from 48 demographically matched individuals (16 schizophrenia patients, 16 subjects with AS and 16 healthy individuals). The surface-based analysis via Freesurfer enabled calculation of cortical thickness, area and folding (local gyrification index, LGI). NSS were examined on the Heidelberg Scale and related to cortical measures. In schizophrenia, higher NSS were associated with reduced cortical thickness and LGI in fronto-temporo-parietal brain areas. In AS, higher NSS were associated with increased frontotemporal cortical thickness. This study lends further support to the hypothesis that disorder-specific mechanisms contribute to NSS expression in schizophrenia and AS. Pointing towards dissociable neural patterns may help deconstruct the complex processes underlying NSS in these neurodevelopmental disorders. PMID:26708327

  12. Motor imagery in Asperger syndrome: testing action simulation by the hand laterality task.

    Directory of Open Access Journals (Sweden)

    Massimiliano Conson

    Full Text Available Asperger syndrome (AS is a neurodevelopmental condition within the Autism Spectrum Disorders (ASD characterized by specific difficulties in social interaction, communication and behavioural control. In recent years, it has been suggested that ASD is related to a dysfunction of action simulation processes, but studies employing imitation or action observation tasks provided mixed results. Here, we addressed action simulation processes in adolescents with AS by means of a motor imagery task, the classical hand laterality task (to decide whether a rotated hand image is left or right; mental rotation of letters was also evaluated. As a specific marker of action simulation in hand rotation, we assessed the so-called biomechanical effect, that is the advantage for judging hand pictures showing physically comfortable versus physically awkward positions. We found the biomechanical effect in typically-developing participants but not in participants with AS. Overall performance on both hand laterality and letter rotation tasks, instead, did not differ in the two groups. These findings demonstrated a specific alteration of motor imagery skills in AS. We suggest that impaired mental simulation and imitation of goal-less movements in ASD could be related to shared cognitive mechanisms.

  13. Gaze behavior of pre-adolescent children afflicted with Asperger syndrome.

    Science.gov (United States)

    Wiklund, Mari

    2012-01-01

    Asperger syndrome (AS) is a form of high-functioning autism characterized by qualitative impairment in social interaction. People afflicted with AS typically have abnormal nonverbal behaviors which are often manifested by avoiding eye contact. Gaze constitutes an important interactional resource, and an AS person's tendency to avoid eye contact may affect the fluidity of conversations and cause misunderstandings. For this reason, it is important to know the precise ways in which this avoidance is done, and in what ways it affects the interaction. The objective of this article is to describe the gaze behavior of preadolescent AS children in institutional multiparty conversations. Methodologically, the study is based on conversation analysis and a multimodal study of interaction. The findings show that three main patterns are used for avoiding eye contact: (1) fixing one's gaze straight ahead; (2) letting one's gaze wander around; and (3) looking at one's own hands when speaking. The informants of this study do not look at the interlocutors at all in the beginning or the middle of their turn. However, sometimes they turn to look at the interlocutors at the end of their turn. This proves that these children are able to use gaze as a source offeedback. When listening, looking at the speaker also seems to be easier for them than looking at the listeners when speaking PMID:24498701

  14. Effects of multisensory yoga on behavior in a male child with Apert and Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Michaela L Scroggins

    2016-01-01

    Full Text Available This case focused on a 7-year-old boy with Apert and Asperger's syndrome who attended 8, 45 min multisensory yoga sessions, twice a week, during 4-week camp. Results from the pre- and post-tests on Treatment and Research Institute for Autism Social Skills Assessment showed improvements in the total score changes from 19 to 7 for disruptive behaviors. Sparks Target Behavior Checklist scores changed from eight to one showing progression in ability to stay on task. Yoga Pose Rating Scale displayed the transformation in total scores from 80 = emerging to 115 = consistency in pose performance. The field notes revealed the positive development in expressive emotions, social engagement, and decline in looking around. Outside class parent and school behavioral specialist reported the improved ability to self-regulate stress using lion's breath and super brain. These findings indicate an improvement in behaviors that influenced the physical performance, emotional expression, and social interaction after yoga training for this child.

  15. Middle-class mothers' perceptions of peer and sibling victimization among children with Asperger's syndrome and nonverbal learning disorders.

    Science.gov (United States)

    Little, Liza

    2002-01-01

    This article describes the yearly prevalence and frequency of peer and sibling victimization as reported by a large national sample of middle-class mothers of children with Asperger's syndrome and nonverbal learning disorders. An anonymous, mailed survey was sent to families solicited from two national Internet sites for parents of children with Asperger's and nonverbal learning disorders using the Comprehensive Juvenile Victimization scale and three questions designed to measure peer shunning. The overall prevalence rate reported by mothers of peer victimization was 94%. Mothers reported that almost three-quarters of their children had been hit by peers or siblings in the past year and 75% had been emotionally bullied. On the more severe end of peer victimization, 10% of the children were attacked by a gang in the past year and 15% were victims of nonsexual assaults to the genitals. Peer shunning also was common. A third of the children had not been invited to a single birthday party in the past year, and many were eating alone at lunch or were picked last for teams. Peer shunning was significantly correlated with peer bullying and assault. The high rates of peer shunning and peer victimization reported suggest that children with Asperger's and nonverbal learning disorders may require further scrutiny and attention concerning their victimization experiences by peers and siblings. Implications for nursing professionals are reviewed. PMID:11934121

  16. Subjective face recognition difficulties, aberrant sensibility, sleeping disturbances and aberrant eating habits in families with Asperger syndrome

    OpenAIRE

    Källman Tiia; Sarenius Susan; Ylisaukko-Oja Tero; Paavonen Juulia E; Nieminen-von Wendt Taina; Järvelä Irma; von Wendt Lennart

    2005-01-01

    Abstract Background The present study was undertaken in order to determine whether a set of clinical features, which are not included in the DSM-IV or ICD-10 for Asperger Syndrome (AS), are associated with AS in particular or whether they are merely a familial trait that is not related to the diagnosis. Methods Ten large families, a total of 138 persons, of whom 58 individuals fulfilled the diagnostic criteria for AS and another 56 did not to fulfill these criteria, were studied using a struc...

  17. Asperger syndrome in India: Findings from a case-series with respect to clinical profile and comorbidity

    Directory of Open Access Journals (Sweden)

    Priya Sreedaran

    2015-01-01

    Full Text Available Asperger syndrome (AS is an autism spectrum disorder with a high rate of psychiatric comorbidity. We describe the clinical profile and psychiatric comorbidity in a series of affected individuals referred to an Indian general hospital psychiatry setting. Gilliam Asperger′s disorder scale was used to evaluate the clinical characteristics while Mini-International Neuropsychiatric Interview (MINI-KID and MINI-PLUS were used to assess psychiatric comorbidity. The profile of subjects with AS in our case-series appears similar to that published elsewhere with high rates of psychiatric comorbidity. Mental health professionals should evaluate for psychiatric comorbidity in individuals with autism spectrum disorders.

  18. Performance of children and adolescents with Asperger syndrome or high-functioning autism on advanced theory of mind tasks

    DEFF Research Database (Denmark)

    Kaland, Nils; Callesen, Kirsten; Møller-Nielsen, Annette;

    2008-01-01

    Although a number of advanced theory of mind tasks have been developed, there is a dearth of information on whether performances on different tasks are associated. The present study examined the performance of 21 children and adolescents with diagnoses of Asperger syndrome (AS) and 20 typically...... developing controls on three advanced theory of mind tasks: The Eyes Task, the Strange Stories, and the Stories from Everyday Life. The participants in the clinical group demonstrated lower performance than the controls on all the three tasks. The pattern of findings, however, indicates that these tasks may...

  19. Learning efficacy of explicit visuomotor sequences in children with attention-deficit/hyperactivity disorder and Asperger syndrome

    OpenAIRE

    Watanabe, Katsumi; Ikeda, Hanako; Miyao, Masutomo

    2010-01-01

    Developmental disorders such as attention-deficit/hyperactivity disorder (ADHD) and Asperger syndrome (AS) are often associated with learning disabilities. This study investigated the explicit learning of visuomotor sequences in 17 ADHD children (mean age 12.1), 21 AS children (mean age 12.7), and 15 typically developing children (mean age: 12.3). The participants were required to explore a hidden sequence of button presses by trial and error and elaborate the learned sequence (2 × 10 task: H...

  20. Uma breve revisão histórica sobre a construção dos conceitos do Autismo Infantil e da síndrome de Asperger A brief historic review of the conceptions of Autism and Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Ana Carina Tamanaha

    2008-01-01

    Full Text Available O objetivo deste estudo foi revisar historicamente os conceitos do Autismo Infantil e da síndrome de Asperger. Por meio de revisão de literatura os autores buscaram mostrar as modificações, ao longo do tempo, das concepções teóricas e das descrições clínicas destes quadros.The aim of this study was to review historically the concepts of Autism and Asperger syndrome. Through literature review, the authors evidence the changes on theoretical concepts and clinical descriptions of Autism and Asperger syndrome with time.

  1. Insomnia in school-age children with Asperger syndrome or high-functioning autism

    Directory of Open Access Journals (Sweden)

    Smedje Hans

    2006-04-01

    Full Text Available Abstract Background Asperger syndrome (AS and high-functioning autism (HFA are pervasive developmental disorders (PDD in individuals of normal intelligence. Childhood AS/HFA is considered to be often associated with disturbed sleep, in particular with difficulties initiating and/or maintaining sleep (insomnia. However, studies about the topic are still scarce. The present study investigated childhood AS/HFA regarding a wide range of parent reported sleep-wake behaviour, with a particular focus on insomnia. Methods Thirty-two 8–12 yr old children with AS/HFA were compared with 32 age and gender matched typically developing children regarding sleep and associated behavioural characteristics. Several aspects of sleep-wake behaviour including insomnia were surveyed using a structured paediatric sleep questionnaire in which parents reported their children's sleep patterns for the previous six months. Recent sleep patterns were monitored by use of a one-week sleep diary and actigraphy. Behavioural characteristics were surveyed by use of information gleaned from parent and teacher-ratings in the High-Functioning Autism Spectrum Screening Questionnaire, and in the Strengths and Difficulties Questionnaire. Results Parent-reported difficulties initiating sleep and daytime sleepiness were more common in children with AS/HFA than in controls, and 10/32 children with AS/HFA (31.2% but none of the controls fulfilled our definition of paediatric insomnia. The parent-reported insomnia corresponded to the findings obtained by actigraphy. Children with insomnia had also more parent-reported autistic and emotional symptoms, and more teacher-reported emotional and hyperactivity symptoms than those children without insomnia. Conclusion Parental reports indicate that in childhood AS/HFA insomnia is a common and distressing symptom which is frequently associated with coexistent behaviour problems. Identification and treatment of sleep problems need to be a routine

  2. Comparative analysis of autistic traits and behavioral disorders in Prader-Willi syndrome and Asperger disorder.

    Science.gov (United States)

    Song, Dae Kwang; Sawada, Masayuki; Yokota, Shingo; Kuroda, Kenji; Uenishi, Hiroyuki; Kanazawa, Tetsufumi; Ogata, Hiroyuki; Ihara, Hiroshi; Nagai, Toshiro; Shimoda, Kazutaka

    2015-01-01

    Prader-Willi syndrome (PWS) is a neuro-genetic disorder caused by the absence/loss of expression of one or more paternally expressed genes on chromosome 15 (q11-13). In this study, a comparative analysis of intelligence level and autistic traits was conducted between children with PWS (n = 30; 18 males, 12 females; age = 10.6 ± 2.8 years) and those with Asperger disorder (AD; n = 31; 24 males, 7 females; age = 10.5 ± 3.1 years). The children were compared by age group: lower elementary school age (6-8 years), upper elementary school age (9-12 years), and middle school age (13-15 years). As results, the intelligence levels of children with PWS were significantly lower than those with AD across all age groups. Autistic traits, assessed using the Pervasive Developmental Disorders Autism Society Japan Rating Scale (PARS), revealed that among elementary school age children, those with PWS had less prominent autistic traits than those with AD, however, among middle school age children, those with PWS and AD showed similar prominence. An analysis of the PARS subscale scores by age group showed that while the profiles of autistic traits for children with PWS differed from those of children with AD at elementary school age, the profiles showed no significant differences between the groups at middle school age. The findings suggest that autistic traits in PWS become gradually more prominent with increasing of age and that these autistic traits differ in their fundamental nature from those observed in AD. PMID:25388910

  3. Neurological abnormalities in recent-onset schizophrenia and Asperger-Syndrome

    Directory of Open Access Journals (Sweden)

    DusanHirjak

    2014-08-01

    Full Text Available Background: Neurological abnormalities including a variety of subtle deficits such as discrete impairments in sensory integration, motor coordination, and sequencing of complex motor acts are frequently found in patients with schizophrenia and commonly referred to as neurological soft signs (NSS. Asperger-Syndrome (AS is characterized by sensory-motor difficulties as well. However, the question whether the two disorders share a common or a disease-specific pattern of NSS remains unresolved. Method: A total of 78 age- and education-matched participants (26 patients with recent-onset schizophrenia, 26 individuals with AS, and 26 healthy controls were recruited for the study. Analyses of covariance (ANCOVAs, with age, years of education and medication included as covariates, were used to examine group differences on total NSS and the five subscale scores. Discriminant analyses were employed to identify the NSS subscales that maximally discriminate between the three groups. Results: Significant differences among the three groups were found in NSS total score and on the five NSS subscales. The two clinical groups differed significantly in the NSS subscale „motor coordination”. The correct discriminant rate between patients with schizophrenia and individuals with AS was 61.5%. The correct discriminant rate was 92.3% between individuals with AS and healthy controls, and 80.8% between schizophrenia patients and healthy controls, respectively. Conclusions: Our findings provide new evidence for the presence of NSS in AS and lend further support to previously reported difficulties in movement control in this disorder. According to the present results, schizophrenia and AS seem to be characterized by a different pattern of NSS.

  4. Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome.

    Science.gov (United States)

    Chien, Vincent S C; Tsai, Arthur C; Yang, Han Hsuan; Tseng, Yi-Li; Savostyanov, Alexander N; Liou, Michelle

    2016-01-01

    Several neuroimaging studies have suggested that the low spatial frequency content in an emotional face mainly activates the amygdala, pulvinar, and superior colliculus especially with fearful faces(1-3). These regions constitute the limbic structure in non-conscious perception of emotions and modulate cortical activity either directly or indirectly(2). In contrast, the conscious representation of emotions is more pronounced in the anterior cingulate, prefrontal cortex, and somatosensory cortex for directing voluntary attention to details in faces(3,4). Asperger's syndrome (AS)(5,6) represents an atypical mental disturbance that affects sensory, affective and communicative abilities, without interfering with normal linguistic skills and intellectual ability. Several studies have found that functional deficits in the neural circuitry important for facial emotion recognition can partly explain social communication failure in patients with AS(7-9). In order to clarify the interplay between conscious and non-conscious representations of emotional faces in AS, an EEG experimental protocol is designed with two tasks involving emotionality evaluation of either photograph or line-drawing faces. A pilot study is introduced for selecting face stimuli that minimize the differences in reaction times and scores assigned to facial emotions between the pretested patients with AS and IQ/gender-matched healthy controls. Information from the pretested patients was used to develop the scoring system used for the emotionality evaluation. Research into facial emotions and visual stimuli with different spatial frequency contents has reached discrepant findings depending on the demographic characteristics of participants and task demands(2). The experimental protocol is intended to clarify deficits in patients with AS in processing emotional faces when compared with healthy controls by controlling for factors unrelated to recognition of facial emotions, such as task difficulty, IQ and

  5. The Effect of Diagnostic Labels on the Affective Responses of College Students towards Peers with "Asperger's Syndrome" and "Autism Spectrum Disorder"

    Science.gov (United States)

    Brosnan, Mark; Mills, Elizabeth

    2016-01-01

    Given the removal of Asperger's Syndrome label in "Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition," the impact of clinical labels upon the affective responses of college students was explored. A total of 120 college students read two vignettes depicting social interactions typical of a person with autism spectrum…

  6. Using Photos and Visual-Processing Assistive Technologies to Develop Self-Expression and Interpersonal Communication of Adolescents with Asperger Syndrome (AS)

    Science.gov (United States)

    Shrieber, Betty; Cohen, Yael

    2013-01-01

    The purpose of this paper is to examine the use of photographs and assistive technologies for visual information processing as motivating tools for interpersonal communication of adolescents with Asperger Syndrome (AS), aged 16 to 18 years, attending special education school. Students with AS find it very difficult to create social and…

  7. Camp Campus: College Preparation for Adolescents and Young Adults with High-Functioning Autism, Asperger Syndrome, and Other Social Communication Disorders

    Science.gov (United States)

    Retherford, Kristine S.; Schreiber, Linda R.

    2015-01-01

    Camp Campus is a 1-week campus experience for juniors or seniors in high school or high school graduates who are diagnosed with high-functioning autism, Asperger syndrome, or a related social communication disorder and who plan to attend college. Participants experience campus life by partaking of campus services, living and dining on campus,…

  8. A Comparison of Video Feedback and in Vivo Self-Monitoring on the Social Interactions of an Adolescent with Asperger Syndrome

    Science.gov (United States)

    State, Talida M.; Kern, Lee

    2012-01-01

    Difficulties with social interactions and restrictive and repetitive interest patterns or behaviors are common among individuals with Asperger syndrome. These difficulties often pose barriers to establishing and maintaining social relationships. In the current study, 2 different interventions were compared that focused on improving the social…

  9. Health-Related Quality of Life and Cognitive Functioning from the Perspective of Parents of School-Aged Children with Asperger's Syndrome Utilizing the PedsQL[TM

    Science.gov (United States)

    Limbers, Christine A.; Heffer, Robert W.; Varni, James W.

    2009-01-01

    HRQOL as a multidimensional construct has not been previously investigated in children with Asperger's Syndrome. The objective of the present study was to examine the initial feasibility, reliability, and validity of the PedsQL[TM] 4.0 Generic Core Scales and PedsQL[TM] Cognitive Functioning Scale parent proxy-report versions in school-aged…

  10. Group Training in Interpersonal Problem-Solving Skills for Workplace Adaptation of Adolescents and Adults with Asperger Syndrome: A Preliminary Study

    Science.gov (United States)

    Bonete, Saray; Calero, María Dolores; Fernández-Parra, Antonio

    2015-01-01

    Adults with Asperger syndrome show persistent difficulties in social situations which psychosocial treatments may address. Despite the multiple studies focusing on social skills interventions, only some have focused specifically on problem-solving skills and have not targeted workplace adaptation training in the adult population. This study…

  11. The Use of "Circle of Friends" Strategy to Improve Social Interactions and Social Acceptance: A Case Study of a Child with Asperger's Syndrome and Other Associated Needs

    Science.gov (United States)

    O'Connor, Eileen

    2016-01-01

    The study outlined here was an attempt to examine the use of "Circle of Friends" as a single intervention approach in addressing the issue of inappropriate social interactions in a child with Asperger Syndrome. The child selected was in a mainstream setting, as the main feature of a circle of friends is peers supporting peers. The child…

  12. A Phenomenological Inquiry into the Perceptions of Software Professionals on the Asperger's Syndrome/High Functioning Autism Spectrum and the Success of Software Development Projects

    Science.gov (United States)

    Kendall, Leslie R.

    2013-01-01

    Individuals who have Asperger's Syndrome/High-Functioning Autism, as a group, are chronically underemployed and underutilized. Many in this group have abilities that are well suited for various roles within the practice of software development. Multiple studies have shown that certain organizational and management changes in the software…

  13. Automatic conversational scene analysis in children with Asperger syndrome/high-functioning autism and typically developing peers.

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    Alessandro Tavano

    Full Text Available Individuals with Asperger syndrome/High Functioning Autism fail to spontaneously attribute mental states to the self and others, a life-long phenotypic characteristic known as mindblindness. We hypothesized that mindblindness would affect the dynamics of conversational interaction. Using generative models, in particular Gaussian mixture models and observed influence models, conversations were coded as interacting Markov processes, operating on novel speech/silence patterns, termed Steady Conversational Periods (SCPs. SCPs assume that whenever an agent's process changes state (e.g., from silence to speech, it causes a general transition of the entire conversational process, forcing inter-actant synchronization. SCPs fed into observed influence models, which captured the conversational dynamics of children and adolescents with Asperger syndrome/High Functioning Autism, and age-matched typically developing participants. Analyzing the parameters of the models by means of discriminative classifiers, the dialogs of patients were successfully distinguished from those of control participants. We conclude that meaning-free speech/silence sequences, reflecting inter-actant synchronization, at least partially encode typical and atypical conversational dynamics. This suggests a direct influence of theory of mind abilities onto basic speech initiative behavior.

  14. A descriptive social and health profile of a community sample of adults and adolescents with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Tantam Digby

    2010-11-01

    Full Text Available Abstract Background Little is known about the health and social profile of adolescents and adults with Asperger syndrome (AS living in the community. We conducted a study to describe the living, employment and psycho-social situation of a community sample of forty two adults and adolescents with AS, and to describe these indivdiuals' experiences of accessing health services and taking medication. Findings Most respondents (including those over eighteen years of age lived at home with their parents. Most had trouble reading and responding to other people's feelings, and coping with unexpected changes. Difficulties with life skills, such as cleaning, washing and hygiene were prevalent. The majority of respondents were socially isolated and a large minority had been sexually or financially exploited. Almost all respondents had been bullied. Mental health problems such as anxiety or depression were common. 30% of respondents said that they regularly became violent and hit other people and 15% had attempted suicide. More positively, the majority of respondents felt that they could access health services if they had a health problem. Conclusions The results of this study suggest a relatively poor social and health profile for many people with Asperger syndrome living in the community, with high levels of social problems and social exclusion, and difficulties managing day to day tasks such as washing and cleaning; these findings support the results of other studies that have examined psycho-social functioning in this group.

  15. Impaired social cognition processes in Asperger syndrome and anorexia nervosa. In search for endophenotypes of social cognition.

    Science.gov (United States)

    Kasperek-Zimowska, Beata Joanna; Zimowski, Janusz Grzegorz; Biernacka, Katarzyna; Kucharska-Pietura, Katarzyna; Rybakowski, Filip

    2016-01-01

    A growing number of publications indicates presence of significant deficits in social cognition in patients with anorexia nervosa (AN). These deficits appear to be comparable in qualitative and quantitative dimension with impairment of the same functions among people with Asperger syndrome (AS). The aim of this study is to identify subject areas in the field of impairment of social cognition processes among people with Asperger syndrome and anorexia nervosa taking into consideration the potential contribution of genetic pathways of oxytocin and vasopressin in the pathogenesis of these diseases. In the first part of the paper a systematic analysis of studies aimed at the evaluation of the processes of social cognition among patients with AN and AS has been carried out. The results of a significant number of studies confirm the presence of deficits in social cognition in AN and AS. In addition, among patients with AN and AS there exists a similar structure and distribution of the brain functions in regions responsible for social cognition. The second part of the paper describes the role of the oxytocin-vasopressin system (OT-AVP) in the processes of social cognition in AN and AS. Its genetic basis and the possible importance of single nucleotide polymorphisms within the genes: OXT, AVP, CD38, OXTR, AVPR1A and LNPEP have also been presented. PMID:27556112

  16. Beyond the others’ world : An essay about the experience of social work with a diagnosis of Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Natalia Shavrina

    2015-03-01

    Full Text Available The essay presents a reflection on being a foreign and inexperienced social worker within a Norwegian social work context. I discuss challenges I have met in my work with when Asperger syndrome is diagnosed and reflect on power relations and the issue of self-determination within the field, in addition to analysing some critical incidents that made me rethink and reconstruct all of my experiences. I view my story from different angles and find different perspectives that show various ways of perceiving one thing. I discover the dangerousness of thinking in “black and white” and placing things in exclusive extremes, and lastly, I understand that I need to learn to solve problems by changing attitudes towards them.

  17. Groene asperges

    NARCIS (Netherlands)

    Poll, J.T.K.

    2000-01-01

    Deze teelthandleiding heeft hoofdzakelijk betrekking op de normale teelt van groene asperges en de vervroegde teelt onder tunnels. Vanwege de toenemende belangstelling voor de biologische teeltwijze van (groene) asperges zijn in deze handleiding mogelijkheden genoemd die in een biologische teelt van

  18. The effect of diagnostic labels on the affective responses of college students towards peers with 'Asperger's Syndrome' and 'Autism Spectrum Disorder'.

    Science.gov (United States)

    Brosnan, Mark; Mills, Elizabeth

    2016-05-01

    Given the removal of Asperger's Syndrome label inDiagnostic and Statistical Manual of Mental Disorders-Fifth Edition, the impact of clinical labels upon the affective responses of college students was explored. A total of 120 college students read two vignettes depicting social interactions typical of a person with autism spectrum disorder. In one vignette, they were informed that the character was a typical college student and in the other, the character had a clinical disorder (either autism spectrum disorder, Asperger's Syndrome or Schizophrenia). Participants' affective responses were measured on the Positive and Negative Affect Scale. No significant differences in positive and negative affective responses were found between the clinical labels. However, affective responses were significantly more positive and less negative towards behaviours associated with clinical groups compared to the typical college student. The implications for students disclosing their diagnosis at university are discussed. PMID:26045542

  19. The Mind behind the Message: Advancing Theory-of-Mind Scales for Typically Developing Children, and Those with Deafness, Autism, or Asperger Syndrome

    Science.gov (United States)

    Peterson, Candida C.; Wellman, Henry M.; Slaughter, Virginia

    2012-01-01

    Children aged 3-2 years (n = 184) with typical development, deafness, autism, or Asperger syndrome took a series of theory-of-mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of H. M. Wellman and D. Liu's (2004) 5-step ToM Scale, added a statistically reliable 6th step to the scale…

  20. 3p22.1p21.31 microdeletion identifies CCK as Asperger syndrome candidate gene and shows the way for therapeutic strategies in chromosome imbalances

    OpenAIRE

    Iourov, Ivan Y; Vorsanova, Svetlana G; Voinova, Victoria Y.; Yurov, Yuri B.

    2015-01-01

    Background In contrast to other autism spectrum disorders, chromosome abnormalities are rare in Asperger syndrome (AS) or high-functioning autism. Consequently, AS was occasionally subjected to classical positional cloning. Here, we report on a case of AS associated with a deletion of the short arm of chromosome 3. Further in silico analysis has identified a candidate gene for AS and has suggested a therapeutic strategy for manifestations of the chromosome rearrangement. Results Using array c...

  1. Local Information Processing in Adults with High Functioning Autism and Asperger Syndrome: The Usefulness of Neuropsychological Tests and Self-Reports

    OpenAIRE

    Spek, Annelies A; Scholte, Evert M.; van Berckelaer-Onnes, Ina A.

    2010-01-01

    Local information processing in 42 adults with high functioning autism, 41 adults with Asperger syndrome and 41 neurotypical adults was examined. Contrary to our expectations, the disorder groups did not outperform the neurotypical group in the neuropsychological measures of local information processing. In line with our hypotheses, the self-reports did show higher levels of local information processing and a stronger tendency to use systemizing strategies in the two disorder groups. Absent a...

  2. Accommodating Asperger's: An Autoethnography on the Learning Experience in an E-Learning Music Education Program

    Science.gov (United States)

    Farrell, Riley Jarrett

    2013-01-01

    A student with Asperger's Syndrome faces a complex myriad of learning disabilities and social difficulties. The co-morbid conditions of dyslexia, Obsessive Compulsive Disorder, Attention Deficit Disorder, Attention Deficit Hyperactive Disorder and anxiety further complicate Asperger's Syndrome. Asperger's Syndrome and these conditions, singularly…

  3. Subjective face recognition difficulties, aberrant sensibility, sleeping disturbances and aberrant eating habits in families with Asperger syndrome

    Directory of Open Access Journals (Sweden)

    Källman Tiia

    2005-04-01

    Full Text Available Abstract Background The present study was undertaken in order to determine whether a set of clinical features, which are not included in the DSM-IV or ICD-10 for Asperger Syndrome (AS, are associated with AS in particular or whether they are merely a familial trait that is not related to the diagnosis. Methods Ten large families, a total of 138 persons, of whom 58 individuals fulfilled the diagnostic criteria for AS and another 56 did not to fulfill these criteria, were studied using a structured interview focusing on the possible presence of face recognition difficulties, aberrant sensibility and eating habits and sleeping disturbances. Results The prevalence for face recognition difficulties was 46.6% in individuals with AS compared with 10.7% in the control group. The corresponding figures for subjectively reported presence of aberrant sensibilities were 91.4% and 46.6%, for sleeping disturbances 48.3% and 23.2% and for aberrant eating habits 60.3% and 14.3%, respectively. Conclusion An aberrant processing of sensory information appears to be a common feature in AS. The impact of these and other clinical features that are not incorporated in the ICD-10 and DSM-IV on our understanding of AS may hitherto have been underestimated. These associated clinical traits may well be reflected by the behavioural characteristics of these individuals.

  4. La inclusión educativa en el aula regular: Un caso de síndrome de Asperger / Educational Inclusion in the Regular Classroom: an Asperger Syndrome Case

    Directory of Open Access Journals (Sweden)

    Fressy Andrade Ruiz

    2011-10-01

    coordination with the Central America Educational and Cultural Coordination (CECC. The research is qualitative with an interpretative approach. Our main objective was to analyze the process of inclusive education in the regular classroom for a person with Asperger’s Syndrome, defined as a type of social impairment. The case study method was used in this research, as it allows a deeper study. A girl was chosen from a public school in an urban area of San José, Costa Rica. Three techniques were used to obtain information: interviews, questionnaires and documentation (personal file, behavior record, and psychological assessment related to the girl with Asperger. The triangulation of sources was used as a method of analysis. The conclusion of the project was that regular schools may have children miss-diagnosed with Asperger’s Syndrome, and that our schools are still far from achieving inclusive education, but efforts are being made to achieve it. For a more opportune intervention, some recommendations based on this study were provided to the family and the school of the girl with Asperger.

  5. The mind behind the message: Advancing theory of mind scales for typically developing children, and those with deafness, autism, or Asperger Syndrome

    OpenAIRE

    Peterson, Candida C.; Wellman, Henry M.; Slaughter, Virginia

    2012-01-01

    Children aged 3 to 12 years (n=184) with typical development, deafness, autism or Asperger Syndrome took a series of theory-of-mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of Wellman and Liu’s (2004) 5-step ToM scale, added a statistically reliable sixth step to the scale for all diagnostic groups. A key previous finding, divergence in task sequencing for children with autism, was confirmed. Comparisons among diagnostic grou...

  6. Asperger's in the Holmes Family

    Science.gov (United States)

    Altschuler, Eric L.

    2013-01-01

    I show that Mycroft Holmes (Sherlock Holmes' brother) is a formally described case of Asperger's syndrome a half century before Asperger's description of the syndrome. Further, given the genetic similarity and links between the brothers stated by Sherlock, this also cinches the same diagnosis for Sherlock.

  7. History and First Descriptions of Autism: Asperger Versus Kanner Revisited.

    Science.gov (United States)

    Chown, Nick; Hughes, Liz

    2016-06-01

    When reading Michael Fitzgerald's chapter entitled 'Autism: Asperger's Syndrome-History and First Descriptions' in 'Asperger's Disorder' edited by Rausch, Johnson and Casanova, a while ago, one of us was struck by his contention that Kanner was guilty of plagiarism as well as non-attribution of Asperger's 1938 paper 'Das psychisch abnorme kind' (Fitzgerald in Asperger's disorder. Informa Healthcare, New York, 2008) published in a Vienna weekly. Steve Silberman has discovered evidence that Kanner rescued Asperger's chief diagnostician from the Nazis in 1944 so must have been aware of Asperger's work and conclusions. Fitzgerald was on the right track but it appears that Kanner may have plagiarised Asperger's ideas rather than his 1938 paper. PMID:26883648

  8. Asperger syndrome and nonverbal learning difficulties in adult males: self- and parent-reported autism, attention and executive problems.

    Science.gov (United States)

    Hagberg, Bibbi; Billstedt, Eva; Nydén, Agneta; Gillberg, Christopher

    2015-08-01

    A specific overlap between Asperger syndrome (AS) and nonverbal learning difficulties (NLD) has been proposed, based on the observation that, as a group, people with AS tend to have significantly higher verbal IQ (VIQ) than performance IQ (PIQ), one of the core features of NLD. The primary aim was to assess the longer term outcome of NLD--broken down into persistent and transient forms. The present study of 68 individuals was performed in the context of a larger prospective longitudinal study to late adolescence/early adult life of 100 boys with AS. Using self- and parent-report measures, we studied the longer term outcome of the NLD (defined as VIQ > PIQ by 15 points) as regards social communication, repetitive behaviour, attention, and executive function (EF) was studied. Three subgroups were identified: (1) Persistent NLD (P-NLD), (2) Childhood "only" NLD (CO-NLD) and (3) Never NLD (NO-NLD). The P-NLD group had the worst outcome overall. The CO-NLD group had better reported EF scores than the two other AS subgroups. There were no differences between the subgroups regarding social communication, repetitive behaviour, or attentional skills. Low PIQ increased the risk of ADHD symptoms. In the context of AS in males, P-NLD carries a relatively poor outcome, particularly with regard to self-reported EF. However, CO-NLD appears to entail a significantly better outcome. The results underscore the importance of analysing the cognitive profile both at diagnosis and after several years, so as to be able to formulate a realistic prognosis. PMID:25399237

  9. Subjective organisation in the free recall learning of adults with Asperger's syndrome

    OpenAIRE

    Bowler, D.M.; Gaigg, S. B.; Gardiner, J. M.

    2008-01-01

    Single trial methods reveal unimpaired free recall of unrelated words in Asperger’s syndrome (AS). When repeated trials are used (free recall learning), typical individuals show improved recall over trials, subjective organisation of material (SO) and a correlation between free recall and SO. We tested oral (Experiment 1) and written (Experiment 2) free recall over 16 trials in adults with AS and typical individuals. Across both experiments AS participants showed marginally diminished recall....

  10. Inclusion of Immersive Virtual Learning Environments and Visual Control Systems to Support the Learning of Students with Asperger Syndrome

    Science.gov (United States)

    Lorenzo, Gonzalo; Pomares, Jorge; Lledo, Asuncion

    2013-01-01

    This paper presents the use of immersive virtual reality systems in the educational intervention with Asperger students. The starting points of this study are features of these students' cognitive style that requires an explicit teaching style supported by visual aids and highly structured environments. The proposed immersive virtual reality…

  11. The Adult Asperger Assessment (AAA): A Diagnostic Method

    Science.gov (United States)

    Baron-Cohen, Simon; Wheelwright, Sally; Robinson, Janine; Woodbury-Smith, Marc

    2005-01-01

    At the present time there are a large number of adults who have "suspected" Asperger syndrome (AS). In this paper we describe a new instrument, the Adult Asperger Assessment (AAA), developed in our clinic for adults with AS. The need for a new instrument relevant to the diagnosis of AS in adulthood arises because existing instruments are designed…

  12. ”Man vill ju klara sig själv” : Studievardagen för studenter med Asperger syndrom i högre utbildning

    OpenAIRE

    Simmeborn Fleischer, Ann

    2013-01-01

    Sammanfattning Sedan början av 2000-talet har det skett en markant ökning av studier gällande barn och ungdomar och Autism. Dock är det så att den mesta forskningen fortfarande är inom det medicinska området. Endast ett fåtal av studierna rör vuxna med Asperger syndrom (AS) som studerar på högskola/universitet. Samtidigt sker en ökning av personer med AS som söker högre utbildning såsom högskola/universitet, vilket gör forskning gällande personer med diagnosen AS högaktuell. Antalet studenter...

  13. 阿斯伯格综合征患儿19例临床特征研究%Clinical analysis of 19 patients with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    张颖; 徐琼; 刘静; 鲁萍; 徐秀

    2012-01-01

    [Objective] To increase the appreciation of manifestation through the analysis of clinical features in children with Asperger syndrome. (Method] Information on chief complaints, clinical manifestation, family backgrounds, gestational and perinatal factors, and the Wechsler intelligence quotient results of patients with Asperger syndrome from November 2006 to February 2011 were studied. (Results] 1)19 cases were diagnosed with Asperger syndrome at the average age of (80. 7 + 21.4) months and a male to female ratio of 18:1; 2) The most common manifestations were poor peer relationship (100%), attention deficit (94. 7%), difficulty to comprehend semantics (89. 5%), restricted interests (84. 2%), clumsiness (78. 9%), hyperactivity (78. 9%), deficiency in nonverbal communication (73. 7%), repetitive and stereotyped patterns of behaviors (73. 7%);3) There were similar problems in several children's fathers, and most parents especially fathers had high degree;4) Verbal IQ was often higher than performance IQ in Wechsler intelligence. [Conclusion] Manifestations of Asperger syndrome are not only specific but also occult, the clinical recognition of these features is . >f important for early identification and diagnosis.%[目的]探讨阿斯伯格综合征的特点,提高对其认识和诊断水平. [方法]分析2006年11月-2011年2月期间在复旦大学附属儿科医院诊治的阿斯伯格综合征患儿的主诉、临床特点、家庭背景、妊娠期及围生期不良因素、韦氏智力结构特点. [结果]1)确诊的19名患儿,男女比例为18∶1,被诊断的平均年龄为(80.7±21.4)个月;2)最常见的临床表现:伙伴关系不良(100%),注意力障碍(94.7%),语意理解困难(89.5%),局限兴趣(84.2%),动作笨拙(78.9%),多动(78.9%),非语言交流缺陷(73.7%),重复刻板行为(73.7%);3)患儿父亲中有类似问题的占到一定比例,且大多数父母特别是父亲的文化水平较高;4)韦氏智力测评显示大

  14. Inclusion of immersive virtual learning environments and visual control systems to support the learning of students with Asperger syndrome

    OpenAIRE

    Lorenzo Lledó, Gonzalo; Pomares Baeza, Jorge; Lledó Carreres, Asunción

    2013-01-01

    This paper presents the use of immersive virtual reality systems in the educational intervention with Asperger students. The starting points of this study are features of these students' cognitive style that requires an explicit teaching style supported by visual aids and highly structured environments. The proposed immersive virtual reality system, not only to assess the student's behavior and progress, but also is able to adapt itself to the student's specific needs. Additionally, the immer...

  15. Idiom understanding in people with Asperger syndrome/high functioning autism Compreensão de expressões idiomáticas em pessoas com síndrome de Asperger/autismo de alto funcionamento

    Directory of Open Access Journals (Sweden)

    Ioannis Vogindroukas

    2011-12-01

    Full Text Available PURPOSE: To extend previous research in the development of idiom comprehension by investigating this ability in children with Asperger Syndrome (AS or with High Functioning Autism (HFA. METHODS: Three groups participated in the study. The first group consisted of 27 children with AS/HFA (mean age 11.3 years and the other two consisted of typically developing children and adults, respectively. The Comprehension Test of Idiomatic Phrases (CTIP was administered to all participants. RESULTS: Children with AS/HFA had lower performance compared to the other two groups. No difference was found in the performance between the two typically developing groups. Also, there was no significant correlation between the IQ and the performance for the children with AS/HFA, while positive correlations were revealed between performance and age for the two groups of children. CONCLUSION: The results provide further evidence that children with AS/HFA have difficulties in understanding idioms and they confirm their tendency to make literal interpretations. These impairments are irrelevant to their intelligence and they affect their communication with others. The understanding of these difficulties is important in order to find ways to limit the confusion and the misinterpretations which are observed during the communicative acts with this clinic group.OBJETIVO: Ampliar pesquisas anteriores a respeito do desenvolvimento da compreensão de expressões idiomáticas por meio da investigação dessa habilidade em crianças com síndrome de Asperger (AS ou com autismo de alto funcionamento (HFA. MÉTODOS: Três grupos participaram do estudo. O primeiro grupo era composto por 27 crianças com AS/HFA (média de idade 11 anos e 3 meses e os outros dois eram constituídos, respectivamente, por crianças em desenvolvimento típico e adultos. O Teste de Compreensão de Expressões Idiomáticas (CTIP foi aplicado a todos os participantes. RESULTADOS: Crianças com AS/HFA tiveram

  16. Reliability and validity of Asperger Syndrome Screening Scale%Asperger综合征筛查量表的编制及信效度检验

    Institute of Scientific and Technical Information of China (English)

    王馨; 金宇; 静进; 王惠; 徐桂凤; 魏薇; 修丽娟; 杨文翰; 暴芃

    2011-01-01

    Objective: To develop a screening scale for Asperger Syndrome (AS) and explore its reliability and validity.Methods: The items of AS screening scale were selected basing on scale development theory and procedure, and adjusted by item analysis method on the pilot study.Sixty-seven children aged 4 ~11 years who met the AS diagnostic criteria of Diagnostic and Statistical Manual, Fourth Edition (DSM-Ⅳ) and 1050 normal children aged 5 - 11 years from common elementary school were selected, whose parents were arranged to answer the scale to ascertain the demarcation point and test the reliability and validity.Results: The total scale score in AS group was higher than that in normal group (P <0.05).When the total scale score was used to screen for AS, the area under the ROC curve (AUC) was 0.98 (P < 0.01), the demarcation point was 49.The test-retest correlation coefficient r was 0.93, each item test-retest r was all above 0.70, and the internal consistency Cronbach’s α was 0.94.When the DSM-Ⅳ was used to be the golden standard, the correlation coefficient r was 0.72.The results of explore factor analysis (EFA) showed that KMO was 0.95, and 50.0% of the total variation could be explained by 6 factors.The scores of each item except for 2 items and total scale in the AS group were higher than that in the normal group ( P < 0.05).Conclusion: The Asperger Syndrome Screening Scale shows good reliability and validity, and could be used widely.%目的:编制一套符合中国文化、具有较好的信度和效度的Asperger综合征(Asperger syndrome,AS)筛查量表.方法:根据量表编制原理和程序编制成Asperger综合征筛查量表初版,经预调查条目分析调整形成量表终版,选取按照精神障碍诊断与统计手册第4版(DSM-Ⅳ)标准诊断的AS儿童67例(4~11岁)和小学1050名(5~11岁),由家长进行量表的填答,测算量表划界分并检验其信度和效度.结果:AS组儿童量表总得分高于正常组(P<0.05),

  17. Characteristics of intelligence structural in children with Asperger syndrome%Asperger综合征儿童智力特点分析

    Institute of Scientific and Technical Information of China (English)

    王惠; 静进

    2011-01-01

    [Objective] To study the intelligence structure and cognitive features of children with Asperger syndrome, in order to offer reference and evidence for diagnosis and relative research. [Methods] 26 children with AS were evaluated by WISC-IV, and then composite and subtest scores were analyzed. [Results] The FSIQ of AS group was in the normal range, with PRI in the highest and PST in the lowest score. Among the ten core subsets, Similarities ranked the first and Digit Span ranked the lowest. [Conclusions] AS Children have the normal general ability, but have deficit in the cognitive proficiency; mainly reflect in cognitive shifting, working memory and short-term memory.%[目的] 探讨Asperger综合征(Asperger syndrome,AS)儿童的智力结构和认知特点,为相关研究及诊疗提供依据. [方法] 采用韦氏儿童智力测验第4版(Wechsler Intelligence Scale for Children-Fourth Edition,WISC-Ⅳ)对26名符合美国《精神障碍诊断和统计手册》第4版(DSM-Ⅳ)标准诊断的AS儿童[平均(9.53±2.42)岁]进行测试.[结果] 人组AS儿童的总智商(95.69±12.11)在正常范围,知觉推理指数(100.08±13.70)的得分最高,加工速度指数(91.58±11.31)的得分最低.此外,在各分测验中,类同(11.04±3.69)的得分最高,背数(7.88±1.88)的得分最低.[结论] 人组AS儿童具有正常范围的认知水平,但存在明显的执行功能障碍,表现为认知灵活性、工作记忆以及短时记忆等能力相对偏低.

  18. Early screening and diagnosis of Asperger's syndrome (Review)%阿斯博格综合征的早期筛查和诊断(综述)

    Institute of Scientific and Technical Information of China (English)

    王馨; 静进

    2011-01-01

    @@ 阿斯博格综合征(Asperger's syndrome,AS)是一种与儿童孤独症(autism)有相似特征,以社会交往障碍、狭隘的兴趣、重复刻板行为和动作发育不协调,但具有与年龄相符的语言和认知功能为主要表现的广泛性发育障碍(pervasive develop-mental disorder,PDD).目前,一般将PDD称为孤独症谱系障碍(Autism Spectrum Disorders, ASD)[1-3],国内外报道其发病率为2‰~1%(个别报道高达1.5%~2.0%),男女比约为4:1,智商在70以上的高功能PDD,包括高功能孤独症(high functional autism,HFA)和AS,约占总体患者一半以上[4-5].

  19. Profile of intelligence of school-aged children with Asperger syndrome%学龄Asperger综合征儿童智力特征分析

    Institute of Scientific and Technical Information of China (English)

    唐春; 邹小兵; 岑超群; 邓红珠; 邹园园

    2009-01-01

    [目的]探讨Asperger综合征(Asperger syndrome,AS)儿童的智力特征.[方法]选取AS儿童62例(AS组),正常儿童63例(对照组),应用中国修订韦氏儿童智力量表(C-WISC)分别进行测试.[结果]AS组中8.07%智力低下(FIQ<70).AS组FIQ、VIQ、PIQ及11个分测验得分均低于对照组,除知识、分类及填图外,余差异均有显著性(P均<0.05).AS组V-P差值有显著性的比例高于对照组(P<0.05),且VIQ高于PIQ者较多(P<0.01).AS组儿童在Dean因子分析理论中抽象思维、视觉记忆、听觉记忆、社会理解和视觉一运动速度明显低于对照组,而远记忆仅低于对照组,但差异无显著性.[结论]Asperger综合征儿童在多个认知功能方面存在缺陷.

  20. A retrospective analysis of the clinical case records of 'autistic psychopaths' diagnosed by Hans Asperger and his team at the University Children's Hospital, Vienna.

    OpenAIRE

    Hippler, Kathrin; Klicpera, Christian

    2003-01-01

    To date, it is questionable whether the diagnostic criteria for Asperger syndrome (AS) as stated by ICD-10 or DSM-IV still reflect Asperger's original account of 'autistic psychopathy' (AP) from the 1940s. The present study examined 74 clinical case records of children with AP diagnosed by Hans Asperger and his team at the Viennese Children's Clinic and Asperger's private practice between 1950 and 1986. The characteristic features of the children are outlined, including reasons for referral, ...

  1. Asperger综合征儿童的智力结构与临床症状%Relation of intelligence structural to clinical symptoms in children with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    王惠; 静进; 金宇; 刘步云; 王馨

    2013-01-01

    Objective:To analyze the intelligence structure characteristics in Asperger syndrome (AS) children and to explore the relation between intelligence composite index with clinic syndrome.Methods:Totally 54 children were selected,including 27 children who were diagnosed as AS according to the Diagnostic and Statistical Manual of Mental Disorders,Fouth Edition (DSM-Ⅳ) criteria and 27 control children.The two groups children were assessed with the Wechsler Intelligence Scale for Children-Fourth Edition and in the AS group,the Asperger Syndrome Screening Scale was filled by the parents of AS children to assess their clinical symptoms.Results:The AS group scored lower in the full scale intelligence quotient [(96.1 ± 12.0) vs.(105.6 ± 9.4),P < 0.05],perceptual reasoning index [(100.4 ± 13.6) vs.(108.9 ± 11.2),P < 0.05],working memory index [(92.3 ± 10.0) vs.(97.9 ± 9.9),P < 0.05],processing speed index [(92.2 ± 11.5) vs.(107.4 ± 12.8),P < 0.05] and cognitive proficiency index [(90.8 ± 9.3) vs.(102.3 ± 10.6),P < 0.05].Among the 10 core subsets,AS children scored lower than control children in block design [(9.7 ± 3.4) vs.(12.3 ± 2.6),P < 0.05],digit span [(7.9 ± 1.9) vs.(9.0 ±1.9),P <0.05],coding [(8.2±2.2) vs.(11.3 ±3.0),P<0.05] and symbol search [(9.2 ±2.6) vs.(11.6±2.5),P <0.05].There was no canonical correlation between intelligence composite indexes and the scores of clinical symptoms(r =0.34-0.63,Ps > 0.05).Conclusion:Children with AS may have the normal general ability,but lower than the normal.AS children may display a cognitive profile that is general ability index is better than cognitive proficiency index.Further studies investigating the relationship between clinical symptoms and intelligence composite indexes are needed.%目的:探讨Asperger综合征(Asperger syndrome,AS)儿童的智力结构特点及其智力合成指数与其临床症状的相关关系.方法:采用国内修订韦氏儿童智力量表第4

  2. 阿斯伯格综合征男童绘人测验特征分析%Characteristics of human figure drawings in boy children with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    魏薇; 静进; 杨文翰

    2011-01-01

    Objective To study the characters and psychological projection of boy children with Asperger syndrome ( AS) in Human Figure Drawings( HFDs). Methods By using HFDs and Eysenck Personality Questionnaire( EPQ), 16 boys with AS and 16 control boys were tested to analyze the Koppitz emotional index and characters of EPQ. Results There were statistical significant difference between two groups on Koppitz motional index and total score of EPQ ( P < 0. 05 ). The boys with AS group had higher scores in all emotional indicators in HFDs (P<0.05) and E, N and P scales in EPQ ( P <0.01 ) than control group, although lower scores in L scales in EPQ ( P < 0.01 ) . It indicated that the T scores of E and N scales in EPQ positively correlated with the scores of emotional indicators in human figure drawings ( P < 0. 05 ). Conclusion Human figure drawings could reflect some emotional characters of AS. To combine some other standard test, it could offer some effective reference to diagnose and intervene AS.%目的 探讨阿斯们格综合征(Asperger syndrome,As)男童在绘人测验中的表现特征和心理投射机制,为相关群体的研究和干预提供参考依据.方法 采用国内标准化绘人测验(HFDs)与艾森克个惟问卷(EPQ),对16名AS男童和1:1配对的16例对照组儿童进行测试,分析AS儿童在绘人测验当中Koppitz情绪指标以及EPQ测试特点.结果 AS儿童和对照组儿童在绘人测验Koppiz情绪指标上的差异及EPQ各量表T分的差异均有统计学意义(p值均<0.05),其中AS组儿童在反映手的焦虑、强迫倾向、社会退缩、情绪不稳定、其他指标得分(肢体不对称、人物有牙齿等)及情绪指标总分均高于对照组(P值均<0.05);AS组在EPQ的E,N,P分量表T分均高于对照组(P值均<0.01),而在L量表T分上AS儿童得分低于对照组(P<0.01).2组绘人测验的各项情绪指标与EPQ的E和N量表分之间呈线性正相关(P<0.05).结论 AS儿童存在不同程度情绪问

  3. Health-related quality of life in parents of school-age children with Asperger syndrome or high-functioning autism

    Directory of Open Access Journals (Sweden)

    Smedje Hans

    2006-01-01

    Full Text Available Abstract Background The estimated prevalence rate of Pervasive Developmental Disorders (PDD in children is 6 per 1.000. Parenting children who are intellectually impaired and have PDDs is known to be linked to the impaired well-being of the parents themselves. However, there is still little available data on health-related quality of life (HRQL in parents of children with Asperger Syndrome (AS and High-Functioning Autism (HFA, or other PDD diagnoses in children of normal intelligence. The present study aimed to evaluate aspects of HRQL in parents of school-age children with AS/HFA and the correlates with child behaviour characteristics. Methods The sample consisted of 31 mothers and 30 fathers of 32 children with AS/HFA and 30 mothers and 29 fathers of 32 age and gender matched children with typical development. Parental HRQL was surveyed by the use of the 12 Item Short Form Health Survey (SF-12 which measures physical and mental well-being. The child behaviour characteristics were assessed using the structured questionnaires: The High-Functioning Autism Spectrum Screening Questionnaire (ASSQ and The Strengths and Difficulties Questionnaire (SDQ. Results The mothers of children with AS/HFA had lower SF-12 scores than the controls, indicating poorer physical health. The mothers of children with AS/HFA also had lower physical SF-12 scores compared to the fathers. In the AS/HFA group, maternal health was related to behaviour problems such as hyperactivity and conduct problems in the child. Conclusion Mothers but not fathers of children with AS/HFA reported impaired HRQL, and there was a relationship between maternal well-being and child behaviour characteristics.

  4. Psychiatric comorbidity of school-age children with Asperger syndrome: a preliminary and clinic-based study%学龄Asperger综合征儿童精神共患病初步研究

    Institute of Scientific and Technical Information of China (English)

    岑超群; 唐春; 邹小兵; 李建英; 邓红珠

    2011-01-01

    [目的] 初步探讨学龄Asperger综合征(Asperger syndrome,AS)儿童共患精神疾病的模式,为系统评估及合适的干预计划提供依据. [方法] 对11 7例门诊确诊为Asperger综合征(采用DSM-Ⅳ标准)的学龄儿童进行回顾性分析,调查他们共患其它精神障碍的模式及有关因素. [结果] 发现超过一半以上患者(59.8%)共患至少一种精神疾病,其中以ADHD最常见,占87.1%,而且共患病往往是多重的,占22.9%.无精神共患病的AS儿童其平均VIQ、FIQ(分别106.1±18.2;99.3±18.6)显著高于有精神共患病的AS儿童平均VIQ、PIQ(分别96.6士19.7;89.5±19.6)(P<0.05),两者的PIQ差异无统计学意义(P>0.05). [结论] AS患者共患其它精神疾病是一个普遍现象,临床中对AS儿童应常规进行精神共患病筛查以便得到及时有效的治疗.%[ObjectiveJ To study the pattern of psychiatric comorbidity in school-age children with Asperger syn-drome which may provide evidence for making a comprehensive intervention plans for them. [Methods] A follow-up study of a clinic sample of 117 school-age children with Asperger syndrome was conducted a retrospective review to examine the psychiatric disorders associated with them. [Results] More than half (59. 8%)had at least one another psychiatric disorder diagnosis in which attention deficit hyperactivity disorder was the most common which accounted for 87. 1 %, and 22. 9% of the comorbid psychiatric disorders were multiple. There were significant differences in VIQ,FIQ but not in PIQ between children with and without psychiatric comorbidity. No statistically significant difference was found with respect to gender whether the psychiatric comorbidity was diagnosed. [Conclusion] Psychiatric comorbidity in Asperger syndrome is very common, routine evaluation of psychiatric comorbidity in children with AS is necessary so that they can get appropriate treatments.

  5. Essential Points of a Support Network Approach for School Counselors Working with Children Diagnosed with Asperger's

    Science.gov (United States)

    Guo, Yuh-Jen; Wang, Shu-Ching; Corbin-Burdick, Marilyn F.; Statz, Shelly R.

    2013-01-01

    Asperger Syndrome (AS) presents unique challenges to both families and schools. Children diagnosed with Asperger's possess unparalleled characteristics in cognitive functioning and behavioral pattern. These children need extra attention and assistance in schools. School counselors require a strategy to successfully engage and support these…

  6. Study on Communication and Adaptive Function of Children with Asperger Syndrome%Asperger 综合征患儿社会适应能力及言语特征研究

    Institute of Scientific and Technical Information of China (English)

    郗春艳; 徐春秀; 赵亚茹

    2004-01-01

    目的:探讨Asperger 综合征(AS)患儿的社会适应能力和言语交流特征,为其有效干预提供依据.方法:采用韦氏儿童智力量表、社会适应能力量表对23 名AS患儿和23名正常对照儿童进行评定;采用自编调查表调查患儿的言语交流特征.结果:AS患儿社会适应能力总分及社交、交流和自我管理能力的得分均明显低于对照组儿童;并表现有不同程度的异常交流行为.结论:AS 患儿的社会适应能力显著低于正常儿童,如能早期诊断和干预,可减少患儿入学后的适应障碍.

  7. Teachers' Social Representation of Students with Asperger Diagnosis

    Science.gov (United States)

    Linton, Ann-Charlotte; Germundsson, Per; Heimann, Mikael; Danermark, Berth

    2013-01-01

    While progress has been made for including students with disability into mainstream schools, trends point to problems for students with Asperger syndrome (AS) diagnosis who have a propensity to dropping out of school. Teachers' perceptions and understanding of AS will affect expectations and the attainment of educational targets. Thus, to…

  8. Asperger综合征114例患儿智力特征分析%The intelligence profiles of 114 children with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    岑超群; 曾小璐; 梁亚勇; 唐春; 邹小兵

    2012-01-01

    Objective The intellectual profiles of children with AS were studied in order to better interpret their behavioral characteristics.Methods Totally 114 children of 6.08~ 14.24 years old with AS were examined by the China-Wechsler Intelligence Scale for Children (C-WISC) and all subtests were administrated.Results The level of intelligence of chidren ranged from mildly impaired to very superior; the average verbal intelligence quotient, (VIQ) .performance intelligence quotient(PIQ)and full intelligence quotient(FIQ) were respectively 101.52+18.72, 88.30±17.40 and 94.90± 17.75; There was statistically significant difference between the VIQ and PIQ among children with AS and a tendency of VIQ > PIQ was showed (P< 0.01). The differences between scores on three Kaufman factors was significant (P<0.0l). Children with AS scored the highest on similarity, vocabulary and information subtests and scored the lowest on picture completion, picture arrangement and coding subsets in full scale; score on comprehension subtest was the lowest in the verbal scale and scores on block design and object assembly subtest were the highest in performance scale. Conclusion The intelligence structures of children with AS are not balanced, which is characterized by a combination of assets and deficits.%目的 探讨Asperger综合征(Asperger syndrome,AS)患儿智力特征,以更好理解和解释其行为表现,为诊断和临床干预提供依据.方法 2002年12月至2009年12月中山大学附属第三医院儿童发育行为专科114例首诊为AS患儿,年龄6岁1个月至14岁3个月,平均(8.31±1.93)岁.均进行韦氏儿童智力量表(C-WISC)测试,分析结果.结果 智商分布从轻度智力低下至智力超常,平均言语智商(VIQ)、操作智商(PIQ)和总智商(FIQ)分别为( 101.52±18.72)、(88.30±17.40)和(94.90±17.75);AS患儿存在显著(VIQ-PIQ)差距(P<0.01),总趋势是VIQ>PIQ(P< 0.01);Kaufman三因子间得分差异有统计学意义(P<0.01);各

  9. Jeg vil greie tingene på egen hånd! En kvalitativ studie av hvilke utfordringer ungdom med diagnosen Asperger syndrom møter i overgangen til et voksent liv og hvilke holdninger de har til å få hjelp utenfra

    OpenAIRE

    Langøy, Emmy Elizabeth

    2013-01-01

    Summary Background: In recent years there has been a strong increase in the number of people with ASD (Autism Spectrum Disorder), including people with Asperger Syndrome (AS). This means that there are a significant number of people in the population of adolescents with this condition. At the same time we seem to live in an individualized culture, where succeeding in most areas is important. The elements that constitute a successful adolescent have probably not been more complex ever. One ...

  10. Nella stanza di Asperger...

    Directory of Open Access Journals (Sweden)

    Alessandra Gilardini

    2011-09-01

    Full Text Available Gli studi sulla struttura del cervello di persone con Asperger avrebbero mostrato una diversa conformazione del lobo parietale (deputato all’elaborazione di soluzioni ai problemi, del lobo temporale mediale (sede della memoria a lungo termine e del cervelletto (coordinatore del movimento corporeo. Queste differenze possono spiegare le capacità a volte geniali di questi bambini e di questi adulti, oltre alla caratteristica ritualità nei gesti che li accompagna nel quotidiano.

  11. Cortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study

    OpenAIRE

    Jou, Roger J.; Minshew, Nancy J.; Keshavan, Matcheri S.; Hardan, Antonio Y.

    2010-01-01

    The validity of Asperger disorder as a distinct syndrome from autism is unclear partly due to the paucity of differentiating neurobiological evidence. Frontal lobe cortical folding between these disorders was compared using the gyrification index. Twenty-three boys underwent structural magnetic resonance imaging: six with high-functioning autism, nine with Asperger disorder, and eight controls. Using the first coronal slice anterior to the corpus callosum, total and outer cortical contours we...

  12. Theory of Mind Tests of Asperger Syndrome in Children%Asperger综合征儿童的心理理论测试

    Institute of Scientific and Technical Information of China (English)

    金宇; 静进; 邹小兵

    2007-01-01

    目的: 研究Asperger 综合征(AS)儿童心理理论测试的完成情况. 方法: 使用中文版"心理理论"测试工具和图片词汇测验(PPVT)测试7~12岁AS儿童32名和正常对照儿童30名. 结果: AS儿童表情辨认测试通过率94%,与正常对照组通过率(100%)比较差异无统计学意义(P=0.494),表情归因测试通过率低于正常对照组(81%,100%,χ2=4.23,P=0.039)."地点变换"和"内容变换"两项错误信念测试通过率分别为69%和63%,均明显低于正常对照组通过率(100%,97%,χ2=8.99、10.91,P=0.003,0.001). 结论: 部分学龄期AS儿童缺乏表情归因和判断他人错误信念的能力.

  13. 学龄Asperger综合征患儿行为问题分析%Behavior Problems of School Aged Children with Asperger Syndrome

    Institute of Scientific and Technical Information of China (English)

    郗春艳; 赵云静; 赵亚茹

    2005-01-01

    Asperger综合征(Asperger Syndrome,AS)是以显著的社交障碍和狭窄刻板的兴趣、行为为特征,但语言和认知发育正常的广泛性发育障碍。最初由Asperger提出,并被美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)分类为广泛性发育障碍(Pervasive Developmental Disorders.PDD)。与孤独症不同的是,AS患儿智力发育正常,因此多能正常入学,但入学后是否存在明显的适应障碍文献少有报道。我们对一组学龄期AS患儿进行了分析,旨在为患儿的正确干预提供依据。

  14. 阿斯伯格综合征男童的眼动抑制缺陷对照研究%Inhibitory deficits of oculomotor behavior in children with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    魏薇; 静进; 金宇; 李秀红; 杨文翰; 王惠

    2010-01-01

    [目的]探讨阿斯伯格综合征(Asperger syndrome,AS)男童在抑制性眼动任务中的反应特征. [方法]采用注视、朝向眼动及反向眼动任务对15例AS男童和15例正常对照男童进行评估. [结果]1)注视任务中,AS组侵入性眼跳数目高于对照组[无分心条件:(12.58±5.63)vs(7.16±3.33),t=3.210,P=0.003;分心条件:(18.36±6.04)vs(12.85±4.10),t=2.919,P=0.007];2)朝向眼动任务中,两组男童眼跳参数差异无统计学意义;3)反向眼动任务中,AS组眼跳方向错误率高于对照组[间隔条件:(66.41±11.78)%vs(52.62±9.58)%,t=3.519,P=0.002;重叠条件:(62.20±11.64)%vs(49.16±9.96)%,t=3.298,P=0.003]. [结论]AS男童眼动抑制能力存在缺陷,表现为内源性眼跳激活不足,提示AS男童可能存在额叶皮层和基底神经核功能紊乱.

  15. Characteristics of facial expression recognition in children with Asperger syndrome%阿斯伯格综合征儿童对人物基本面部表情的识别特点

    Institute of Scientific and Technical Information of China (English)

    郭嘉; 静进; 邹小兵; 唐春

    2011-01-01

    目的:了解阿斯伯格综合征(Asperger syndrome,As)儿童对人物基本面部表情的识别能力和特征.方法:使用本研究研发的面部表情识别测试软件系统对22例符合美国精神障碍诊断和统计手册第四版(the Diagnostic and Statistical Manual of Mental Disorders,4th edition,DSM-Ⅳ)AS诊断标准的门诊AS儿童和20例性别、年龄等一般情况相匹配的正常对照儿童进行测试.以不同呈现方式下的面部表情识别的正确率与反应时为分析指标.结果:AS儿童对正立面部表情、上半部面孔表情的识别正确率均低于正常对照儿童,且反应时间延迟.AS儿童对整体面部表情的识别仅优于下半面孔,而正常儿童对整体面部表情的识别率优于上半和下半面孔.AS儿童与正常儿童对正立(整体)面孔的识别均优于倒立面孔.结论:阿斯伯格综合征儿童对人物面部表情的识别能力较正常儿童差,但尚具有一定的面孔整体加工能力,与正常儿童同样具有倒置面孔效应.%Objective: To explore the ability and characteristics of facial expression recognition in children with Asperger syndrome (AS) . Methods: Twenty-two male children with AS according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-Ⅳ), and twenty normal children matched on chronological age and gender were selected. They were tested with the Facial Expression Recognition Software System developed in this research which took recognition accuracy rate and response time in different presentation manners as analysis indexes. Results: The accuracy rates of upright and the upper facial expression were significantly lower in children with AS than in normal controls [ upright: ( 60. 4 ± 12. 8 ) % vs. ( 73.8 ± 6. 1 ) % , P < 0. 001; upper:( 53.3 ± 13.3 ) % vs. ( 62. 9 ± 8.5 ) % , P= 0. 009] , and the response time was delayed ( P < 0. 05 ) [ upright:(3.494±0.570) svs. (2.839±0.415) s, P<0.001; upper: (4

  16. Socially ADDept: Teaching Social Skills to Children with ADHD, LD, and Asperger's, Revised Edition

    Science.gov (United States)

    Giler, Janet Z.

    2011-01-01

    "Socially ADDept" helps educators and parents teach the hidden rules of social behavior to children with limited social skills, notably those with special needs like ADHD, learning disabilities, Asperger's and high-functioning autism, Tourette Syndrome, and nonverbal learning disabilities. The author provides all the information parents and…

  17. The Role of Experience in Teachers' Social Representation of Students with Autism Spectrum Diagnosis (Asperger)

    Science.gov (United States)

    Linton, Ann-Charlotte; Germundsson, Per; Heimann, Mikael; Danermark, Berth

    2015-01-01

    Support from teachers is a key strategy for accommodating students with Asperger syndrome (AS) diagnosis in the mainstream classroom. Teachers' understanding and expectations of students, i.e. their social representations (SR), have a bearing on how they interact and accommodate, but little is known about why. Therefore, the current study examined…

  18. Study of central coherence in children with high functioning autism and asperger syndrome%高功能孤独症和Asperger综合征儿童的中央凝聚性研究

    Institute of Scientific and Technical Information of China (English)

    李咏梅; 邹小兵; 李建英; 唐春; 邓红珠; 李巧毅; 陈凯云; 邹圆圆; 鄢月华

    2006-01-01

    [目的]探讨高功能孤独症(high function autism,HFA)和Asperger综合征(Asperger syndrom,AS)儿童在中央凝聚性方面的认知神经心理特征,为其治疗提供理论依据.[方法]应用视觉和言语语义记忆任务和木块图形测验分别对19例学龄前及学龄期HFA儿童、26例AS儿童和20例正常健康儿童(normal controls,NC)进行测试,为其治疗提供理论依据.[结果]在视觉模式或言语模式下,给予语义相关系列的刺激时,三组儿童组能回忆的正确图片或词语数目均比非相关系列刺激能回忆正确的图片或词语数目显著增多(P<0.05);各组儿童在视觉模式下能回忆的图片数目均比在言语模式下能回忆的词语数目显著增多(P<0.01);HFA组儿童在视觉模式相对言语的记忆优势比正常组更明显.HFA组木块图量表分明显低于正常儿童组(P<0.05),AS组量表分与正常儿童组差异无显著性(P>0.05).[结论]学龄前及学龄期HFA和AS儿童的中央凝聚性薄弱并不明显,推测HFA和AS患者的中央凝聚性薄弱的认知特征可能会随着年龄的增长逐渐明显.

  19. Asperger's disorder will be back.

    Science.gov (United States)

    Tsai, Luke Y

    2013-12-01

    This review focuses on identifying up-to-date number of publications that compared DSM-IV/ICD-10 Asperger's disorder (AspD) to Autistic Disorder/High-functioning Autism (AD/HFA). One hundred and twenty-eight publications were identified through an extensive search of major electronic databases and journals. Based on more than 90 clinical variables been investigated, 94 publications concluded that there were statistically significant or near significant level of quantitative and/or qualitative differences between AspD and AD/HFA groups; 4 publications found both similarities and differences between the two groups; 30 publications concluded with no differences between the two groups. Although DSM-5 ASD will eliminate Asperger's disorder. However, it is plausible to predict that the field of ASD would run full circle during the next decade or two and that AspD will be back in the next edition of DSM. PMID:23644916

  20. 高功能孤独症与Asperger综合症患儿行为问题的比较研究%Comparative research of behavior problems between high functioning autism children and Asperger syndrome children

    Institute of Scientific and Technical Information of China (English)

    杭跃跃; 苏艳丽; 洪珊珊; 潘恒足; 邹冰; 柯晓燕

    2009-01-01

    目的 分析比较学龄期高功能孤独症(high functioning autism,HFA)与Asperger综合症(As-perger syndrome,AS)患儿行为问题.方法 应用Achenbach儿童行为量表(Child Behaviour Checklist,CBCL)对20例HFA儿童、25例AS儿童和27例正常儿童行为问题进行调查和比较;通过多元回归分析HFA组和AS组行为问题各因子与年龄关系.结果 (1)HFA组和AS组行为问题各因子分均高于对照组,差异有显著性(P<0.05);(2)HFA组学习能力[(1.96±1.08)分]低于AS组学习能力[(3.13±1.07)分].差异有显著性(P<0.05);(3)HFA组与AS组体诉、交往不良和违纪行为与年龄均有线性回归关系,随年龄的增长而增多,增多的相对程度不同.结论 考虑年龄因素,学龄期HFA儿童和AS儿童行为问题存在差异性,支持AS是广泛性发育障碍的一个独立亚群的观点.%Objective To analyze and compare behavior problems of school aged children between high functioning autism(HFA) and Asperger syndrome(AS). Methods Using the Child Behaviour Checklist(CBCL) to investigate and compare behavior problems of 20 children with HFA,25 children with AS and 27 matched con-trois,and to analyze the relation of behavior problems and age in children with HFA and AS by linear regression. Results (1) Compared with the control group,behavior problems in both HFA group and AS group had a signifi-cant differenee(P<0.05). (2)Compared with the HFA group, scores of learning ability in AS group had a signifi-cant increase [(1.96±1.08) vs (3.13±1.07 ), P<0.05]. (3) There was linear regressive relation between age and the scores of behavior problems such as uncomfortable describing in body, associating disability, violating disci-pline in both HFA and AS group. With the increasing of age, these behavior problems increased, but their increas-ing relative degree was different. Conclusion There are some difference in behavior problems of school age chil-dren between HFA and AS, which supported a view AS is an

  1. Investigation on the comorbidity rates of school-aged Asperger syndrome children with attention deficit hyperactivity disorder and analysis of misdiagnosed reasons to attention deficit hyperactivity disorder%学龄阿斯伯格综合征儿童与注意缺陷多动障碍共患率调查及误诊原因分析

    Institute of Scientific and Technical Information of China (English)

    梁亚勇; 杨翠萍; 岑超群; 邹小兵

    2012-01-01

    [Objective] To investigate the comorbidity rates of school-aged Asperger syndrome children with attention deficit hyperactivity disorder( ADHD) and to analyze the reasons of misdiagnoseing Asperger syndrome to attention deficit hyperactivity disorder. [Methods] Using the Vanderbilt ADHD Rating Scales to evaluate the prevalence of ADHD in out-patient diagnosed 90 Asperger syndrome (AS) children (male 85,female 5) and the 249 control group children(male 223,fe-male 16) ;Investigated the first diagnosis of the 39 AS children who were diagnosed in other hospitals, to got the reasonsthey were misdiagnosed to be attention deficit hyperactivity disorder. [ Results ] There were 44 in the 90 AS children consistent with the diagnose standard of ADHD.it was 48. 7% ;but it was only 9 in 249 common children reach the diagnose standard of ADHD,it was 3. 6% . The prevalence of ADHD in AS children was higher than in common children, thafs having a distinguished statistical significance(x2 = 102. 732,P<0. 01). In the 39 AS children who were first diagnosed in other hospitals,only six children got the correct diagnosis.it was 15. 4% ,the misdiagnosis rate was 84. 6% ,19 children were misdiagnosed of ADHD,it was 48. 7%. (Conclusion] The prevalence of ADHD in school-aged AS children is distinguished higher than normal control group children,and school-aged AS children always be misdiagnosed to be ADHD.%[目的]调查阿斯伯格综合征(Asperger syndrome,AS)学龄儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)的共患率及分析其易误诊为ADHD的原因. [方法]应用Vanderbilt ADHD评定量表对门诊确诊的90例AS患儿(男85例,女5例)评估其ADHD的共患率,并与249例普通学龄儿童(男223例,女16例)ADHD患病率进行对比分析;曾在外院接受诊断的39例AS患儿的首诊情况,分析其误诊为ADHD的原因. [结果]90例AS学龄儿童中,符合ADHD诊断标准者44例(48.9%);249例普通学龄

  2. [Non-autistic pervasive developmental disorders: Rett syndrome, disintegrative disorder and pervasive developmental disorder not otherwise specified

    NARCIS (Netherlands)

    Mercadante, M.T.; Gaag, R.J. van der; Schwartzman, J.S.

    2006-01-01

    The category "Pervasive Developmental Disorders" includes autistic disorder, Asperger's syndrome, Rett's syndrome, childhood disintegrative disorder, and a residual category, named pervasive developmental disorder not otherwise specified. In this review, Rett's syndrome and childhood disintegrative

  3. Asperger综合征共患精神分裂症患者的智商及家族史研究%Comorbid association of Asperger syndrome and schizophrenia

    Institute of Scientific and Technical Information of China (English)

    岑超群; 邹小兵; 唐春; 邓红珠

    2009-01-01

    Objective To study the rate of children with Asperger syndrome (AS) comorbid with schizophrenia and to analyse the related factors. Methods 139 detailed case records of patient (according to DSM-IV criteria ) aged 5.4 ~15.2 were selected for review,and the patients had received comprehensive evaluations and were followed periodically at our center( at least semiannually or twice per year). Results There were five male individuals had a diagnosis of schizophrenia when they aged 10.1~14.0. The average VIQ,PIQ,FIQ of individuals comorbid with schizophrenia were respectively 96.3±15.0,81.7±6.4,88.3±8.0 and outcomes of the rest individuals were respectively 91.8±20.8,88.6±17.7,89.5±18.9,there were no significant statistically difference between two groups( P >0.01). The frequency of psychiatric history of the first or the second family in the individuals comorbid with schizophrenia were higher than that in the individuals without schizophrenia( P <0.01).Conclusion It appears that the frequency of schizophrenia among AS patients is high,which should pay attention to.%目的 探讨Asperger综合征(AS)儿童共患精神分裂症的比例并对相关因素进行分析,为AS的评估和干预提供可能的指导.方法 对采用DSM-IV标准确诊为AS且定期复诊(至少每6个月1次或每年2次),并有详细完整记录的139名5~15岁患者进行回顾性调查分析.结果 有5例AS患者共患精神分裂症,均为男性,年龄为10~14岁.共患精神分裂症组患者平均言语智商(VIQ)、操作智商(PIQ)、总智商(FIQ)分别为(96.3±15.0)分、(81.7±6.4)分、(88.3±8.0)分,非共患组VIQ、PIQ、FIQ分别为(91.8±20.8)分、(88.6±17.7)分、(89.5±18.9)分,2组间差异无显著性( P >0.01);共患组比非共患组有更高比例的一、二级亲属精神病家族史( P <0.01).结论 AS患者共患精神分裂症的比率较高,在临床治疗中应予重视.

  4. Opinions of People Who Self-Identify with Autism and Asperger's on "DSM-5" Criteria

    Science.gov (United States)

    Linton, Kristen Faye; Krcek, Taylor E.; Sensui, Leonard M.; Spillers, Jessica L. H.

    2014-01-01

    Purpose: Autistic disorder (AD), Asperger's syndrome (AS), and pervasive developmental disorder--not otherwise specified (PDD-NOS) have been removed from the "Diagnostic and Statistical Manual of Mental Disorders--Fifth Edition" ("DSM-5"). It now contains the autism spectrum disorder (ASD) diagnosis. This study assessed…

  5. Projektiraportti Asperger-oppaasta : Alueellinen ensitieto-opas Asperger-diagnoosin saaneen lapsen perheelle

    OpenAIRE

    Larinen, Raija

    2010-01-01

    TIIVISTELMÄ KEMI-TORNION AMMATTIKORKEAKOULU Sosiaali- ja terveysala Hoitotyön koulutusohjelma RAIJA LARINEN ENSITIETO-OPAS Asperger-diagnoosin saaneen lapsen perheelle Projektityö:31 sivua + 13 oppaan sivua Ohjaajat: Anne Puro ja Elli Peteri _______________________________________________________________________ Asiasanat: Autismi, autismin kirjo, Aspergerin oireyhtymä Aspergerin oireyhtymä eli Asperger-syndrooma on autismin kirjoon kuuluva neurobiologinen kes...

  6. Representation of Asperger Syndrome in Contemporary Fiction

    OpenAIRE

    Johansen, Kathrine Nyborg

    2015-01-01

    In this thesis address the issue of how point of view and narrative voice within The Curious Incident of the Dog in the Night-time (Mark Haddon 2003), and Mockingbird (Kathryn Erskine 2010) relate to the theoretical models of disability studies. As the analysis will prove, the effect of narrative strategies in the novels serves to underline some of the current challenges within the field of disability studies. Through the literary analysis of the novels, I argue that the two novels describe d...

  7. FINDING PLACE IN A â NEUROTYPICALâ SOCIETY: A PHENOMENOLOGICAL STUDY OF INDIVIDUALS WITH ASPERGERâ S SYNDROME

    OpenAIRE

    Miles, Annette Deborah

    2009-01-01

    Annette Neal-Miles's Abstract In 1944 Hans Asperger, a Viennese physician, identified a neurological disorder which hinders a personâ s ability to communicate and interact socially. Lorna Wingâ s research reintroduced the disorder in 1981, but Aspergerâ s Syndrome was not recognized in the United States until 1994. This study, aimed at generating knowledge about the lived experience of individuals with Aspergerâ s, is grounded in hermeneutic phenomenology. The writ...

  8. Direct and Indirect Measures of Social Perception, Behavior, and Emotional Functioning in Children with Asperger's Disorder, Nonverbal Learning Disability, or ADHD

    Science.gov (United States)

    Semrud-Clikeman, Margaret; Walkowiak, Jenifer; Wilkinson, Alison; Minne, Elizabeth Portman

    2010-01-01

    Understanding social interactions is crucial for development of social competence. The present study was one of the first to utilize direct and indirect measures of social perception to explore possible differences among children with nonverbal learning disability (NLD), Asperger's Syndrome (AS), Attention Deficit Hyperactivity Disorder-Combined…

  9. Exploring the Perception of Asperger's Disorder

    Science.gov (United States)

    Kite, Donna M.; Tyson, Graham A.; Gullifer, Judith M.

    2011-01-01

    With current preparation for the release of the fifth edition of the "Diagnostic and Statistical Manual of Mental Disorders" (DSM-5) in 2013, many changes have been proposed for the diagnostic criteria, including changes to the pervasive development disorder category--of which Asperger's disorder is a part. Using focus group discussions this study…

  10. Effect vocht op de kwaliteit van asperges

    NARCIS (Netherlands)

    Wilms, J.A.M.; Meuffels, G.J.H.M.

    2013-01-01

    Vaststellen invloed van bevochtigen van de bedden op kwaliteit van witte asperges in de tweede helft van het oogstseizoen. Bij het object met T-tape was er op 8 augustus een significant hoger aandeel nieuw schot. Dit kan een voordeel zijn, want vroeg nieuw schot wil zeggen dat er ook een betere assi

  11. Effect vocht op de kwaliteit van asperges

    OpenAIRE

    Wilms, J.A.M.; Meuffels, G.J.H.M.

    2013-01-01

    Vaststellen invloed van bevochtigen van de bedden op kwaliteit van witte asperges in de tweede helft van het oogstseizoen. Bij het object met T-tape was er op 8 augustus een significant hoger aandeel nieuw schot. Dit kan een voordeel zijn, want vroeg nieuw schot wil zeggen dat er ook een betere assimilatie plaats vindt, waardoor de plant meer suikers kan opslaan als reserve voor het volgende oogstseizoen. Dit kan opbrengst verhogend werken.

  12. Superior Fluid Intelligence in Children with Asperger's Disorder

    Science.gov (United States)

    Hayashi, Mika; Kato, Motoichiro; Igarashi, Kazue; Kashima, Haruo

    2008-01-01

    Asperger's disorder is one of autistic spectrum disorders; sharing clinical features with autism, but without developmental delay in language acquisition. There have been some studies of intellectual functioning in autism so far, but very few in Asperger's disorder. In the present study, we investigated abstract reasoning ability, whose form of…

  13. Analysis of Copper and Zinc Plasma Concentration and the Efficacy of Zinc Therapy in Individuals with Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and Autism

    OpenAIRE

    A.J. Russo; Robert deVito

    2011-01-01

    Aim To assess plasma zinc and copper concentration in individuals with Asperger’s Syndrome, Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS) and autistic disorder, and to analyze the efficacy of zinc therapy on the normalization of zinc and copper levels and symptom severity in these disorders. Subjects and methods Plasma from 79 autistic individuals, 52 individuals with PDD-NOS, 21 individuals with Asperger’s Syndrome (all meeting DSM-IV diagnostic criteria), and 18 age and...

  14. Asperger综合征儿童母亲的亲职压力及其相关因素分析%Parenting stress and related factors in mothers of children with asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    唐春; 秦秀群; 李咏梅; 邹小兵

    2010-01-01

    [目的]探讨 Asperger 综合征儿童母亲的亲职压力及其相关因素,为开展心理干预和支持提供科学依据.[方法]使用短型亲职压力量表对81例Asperger综合征儿童母亲及157例正常儿童母亲进行调查,同时使用Achenbach儿童行为量表与韦氏儿童智力量表对81例Asperger综合征儿童进行智力与行为评估.[结果]Asperger综合征儿童母亲的亲职压力总分和各维度得分均高于正常儿童母亲(P<0.001).单因素分析:不同儿童性别、家庭结构、家庭人均月收入,Asperger综合征儿童母亲的亲职压力总分差异有统计学意义(P<0.05).母亲亲职压力总分和各维度得分与儿童的社会能力呈负相关(r分别为-0.348、-0.272、-0.305、-0.356,P<0.01),与儿童的问题行为呈正相关(r分别为0.658、0.516、0.572、0.668,P<0.01).[结论]Asperger综合征儿童母亲亲职压力显著高于正常水平,提高儿童社会能力和矫正儿童问题行为可降低母亲亲职压力.

  15. Biologische teelt en afzetbevordering van (kas)asperge

    NARCIS (Netherlands)

    Bartels, C.; Hulst, van der P.

    2004-01-01

    Dit onderzoek bestond uit twee onderdelen, in de eerste plaats is met behulp van enquêtes de bestaande teelt en afzet van biologische asperges onderzocht, in de tweede plaats zijn er teeltproeven met biologische kasasperges gedaan.

  16. A Review of Co-Morbid Disorders of Asperger's Disorder and the Transition to Adulthood

    Science.gov (United States)

    Robinson, Stephanie; Curwen, Tracey; Ryan, Thomas G.

    2012-01-01

    This review includes empirical peer-reviewed articles which support the examination of Asperger's Disorder and co-morbid disorders, as well as an analysis of how adolescents with Asperger's Disorder transition to adulthood. Although the focus was on Asperger's Disorder, some studies include Autism Spectrum Disorder samples. It was found that…

  17. Normal for an Asperger: Notions of the Meanings of Diagnoses among Adults with Asperger Syndrome

    Science.gov (United States)

    Rosqvist, Hanna Bertilsdotter

    2012-01-01

    This study explores the production of a counterhegemonic discourse of "autistic normalcy" among adults with high-functioning autism by analyzing notions of diagnosis. The discourse analyses are based on material from ethnographic fieldwork in a Swedish educational setting. Study participants were 3 male and 9 female adults who had been diagnosed…

  18. Habilidades sociales y Síndrome de Asperger

    OpenAIRE

    Altadill-Viña, María Desiré

    2014-01-01

    Desde hace unos años, el número de alumnos con NEE (Necesidades Educativas Especiales) ha ido aumentando en las aulas ordinarias. Actualmente, a muchas de ellas llegan alumnos con TGD (Trastorno Generalizado del Desarrollo) o TEA (Trastornos del Espectro Autista). Dentro de los TEA encontramos el Síndrome de Asperger. Para los alumnos con Síndrome de Asperger, esta inclusión dentro de un aula ordinaria es realmente complicada, ya que padecen un déficit en cuanto a habilidades s...

  19. Propuesta de intervención musical por alumnado asperger

    OpenAIRE

    Revuelta López, Miriam

    2015-01-01

    El presente trabajo de fin de grado pretende dar a conocer la influencia que tiene la música sobre el proceso de aprendizaje, concretamente en la mejora de las dificultades de los niños con síndrome de Asperger, un trastorno que se da en el aula. El síndrome de Asperger es un trastorno del desarrollo, incluido desde el 2013 en el DSM- V (Manual diagnóstico y estadístico de los trastornos mentales) donde aparece como un único síndrome, junto al autismo, el desintegrativo infantil y no espe...

  20. Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine

    Science.gov (United States)

    2013-10-31

    Autism Spectrum Disorder (ASD); Autism; Autistic Disorder; Asperger's Disorder; Asperger's; Pediatric Autism; Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS); Pervasive Child Development Disorder

  1. Saccade adaptation in autism and Asperger's disorder.

    Science.gov (United States)

    Johnson, B P; Rinehart, N J; White, O; Millist, L; Fielding, J

    2013-07-23

    Autism and Asperger's disorder (AD) are neurodevelopmental disorders primarily characterized by deficits in social interaction and communication, however motor coordination deficits are increasingly recognized as a prevalent feature of these conditions. Although it has been proposed that children with autism and AD may have difficulty utilizing visual feedback during motor learning tasks, this has not been directly examined. Significantly, changes within the cerebellum, which is implicated in motor learning, are known to be more pronounced in autism compared to AD. We used the classic double-step saccade adaptation paradigm, known to depend on cerebellar integrity, to investigate differences in motor learning and the use of visual feedback in children aged 9-14 years with high-functioning autism (HFA; IQ>80; n=10) and AD (n=13). Performance was compared to age and IQ matched typically developing children (n=12). Both HFA and AD groups successfully adapted the gain of their saccades in response to perceived visual error, however the time course for adaptation was prolonged in the HFA group. While a shift in saccade dynamics typically occurs during adaptation, we revealed aberrant changes in both HFA and AD groups. This study contributes to a growing body of evidence centrally implicating the cerebellum in ocular motor dysfunction in autism. Specifically, these findings collectively imply functional impairment of the cerebellar network and its inflow and outflow tracts that underpin saccade adaptation, with greater disturbance in HFA compared to AD. PMID:23562581

  2. Source Memory in Adolescents and Adults with Asperger's Syndrome

    Science.gov (United States)

    Bowler, Dermot M.; Gardiner, John M.; Berthollier, Natasha

    2004-01-01

    Memory difficulties in autism are observed mainly on measures like free recall, where test procedures provide no support for memory. When support is present, such as in cued recall, difficulties are less evident. Such observations may explain the mixed findings on source memory in autism. Bennetto, Pennington and Rogers (Child Development, 67,…

  3. Dual Familial Roles: An Asperger's Syndrome Case Story

    Science.gov (United States)

    Ivey, Julie K.; Ward, A. Kris

    2010-01-01

    Sibling interactions are challenges that all families face on a daily basis. These interactions are significantly more difficult when one child has autism. With the apparent increase in diagnoses of autism, there are more families each year who are dealing with issues of relationships. Children learn, as part of the growing up experience, how to…

  4. Cyber Bullying in ADHD and Asperger Syndrome Populations

    Science.gov (United States)

    Kowalski, Robin M.; Fedina, Cristin

    2011-01-01

    Cyber bullying or electronic bullying refers to bullying that occurs through the Internet or cellular phones. With the rise of technology, researchers have shown a keen interest in the topic of cyber bullying. However, that interest has not extended to individuals with special needs. To address this gap in the literature, the current study…

  5. Asperger Syndrome and High Functioning Autism Tool Kit

    Science.gov (United States)

    ... communication and repetitive behaviors. With the May 2013 publication of the fifth edition of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (commonly referred to as the ...

  6. The Use of Psychodrama Techniques for Students with Asperger's Disorder

    Science.gov (United States)

    Munir, Samira; Scholwinski, Edward; Lasser, Jon

    2006-01-01

    Asperger's Disorder (AD) is a pervasive developmental disorder affecting social functioning and behavioral interest and activities. The purpose of this article is to inform school counselors of the characteristic features of AD, common interventions being implemented, and the techniques associated with the practice of psychodrama that appear to…

  7. A Scale to Assist the Diagnosis of Autism and Asperger's Disorder in Adults (RAADS): A Pilot Study

    Science.gov (United States)

    Ritvo, Riva Ariella; Ritvo, Edward R.; Guthrie, Donald; Yuwiler, Arthur; Ritvo, Max Joseph; Weisbender, Leo

    2008-01-01

    An empirically based 78 question self-rating scale based on DSM-IV-TR and ICD-10 criteria was developed to assist clinicians' diagnosis of adults with autism and Asperger's Disorder-the Ritvo Autism and Asperger's Diagnostic Scale (RAADS). It was standardized on 17 autistic and 20 Asperger's Disorder and 57 comparison subjects. Both autistic and…

  8. Aripiprazole Improved Obsessive Compulsive Symptoms in Asperger's Disorder.

    Science.gov (United States)

    Celik, Gonca; Tahiroglu, Aysegul Yolga; Firat, Sunay; Avci, Ayşe

    2011-12-01

    There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment case with aripiprazole in Asperger's Disorder with obsessive compulsive symptoms. The Yale Brown Obsessive Compulsive Scale was performed to assess symptom variety. This case report supports the effectiveness of aripiprazole in treatment of obsessive compulsive symptoms in Asperger's Disorder or ASDs. Aripiprazole may be beneficial to obsessive compulsive disorder comorbid autism spectrum disorders in child and adolescent age group. PMID:23429759

  9. Aripiprazole Improved Obsessive Compulsive Symptoms in Asperger's Disorder

    OpenAIRE

    Celik, Gonca; Tahiroglu, Aysegul Yolga; Firat, Sunay; AVCI, Ayşe

    2011-01-01

    There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment case with aripiprazole in Asperger's Disorder with obsessive compulsive symptoms. The Yale Brown Obs...

  10. Qualitative or Quantitative Differences between Asperger's Disorder and Autism? Historical Considerations

    Science.gov (United States)

    Sanders, James Ladell

    2009-01-01

    The histories of autism and Asperger's Disorder (AD), based on original contributions by Kanner and Asperger, are reviewed in relation to DSM-IV diagnostic criteria. Their original articles appear to have influenced the distinction between AD and autism made in the DSM-IV. Based on up-to-date empirical research, however, it appears that AD and…

  11. Can Asperger's Disorder Be Differentiated from Autism Using "DSM-IV" Criteria?

    Science.gov (United States)

    Tryon, Patti Ann; Mayes, Susan D.; Rhodes, Robert L.; Waldo, Michael

    2006-01-01

    Parents of 26 children with diagnoses of Asperger's disorder completed a symptom checklist to determine whether the children met "Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, Text Revision" ("DSM-IV-TR"; American Psychiatric Association, 2000) criteria for Asperger's disorder, autism, or pervasive developmental disorder…

  12. Brief Report: No Increase in Criminal Convictions in Hans Asperger's Original Cohort

    Science.gov (United States)

    Hippler, Kathrin; Viding, Essi; Klicpera, Christian; Happe, Francesca

    2010-01-01

    Hans Asperger originally used the term "autistic psychopathy" to describe his patients on the autism spectrum, leading to a possible confusion with psychopathic disorder and delinquent behaviour. We conducted a penal register search for 177 former patients of Asperger's clinic with a childhood diagnosis of "autistic psychopathy" or features of the…

  13. Lexical Processing in Individuals with High-Functioning Autism and Asperger's Disorder

    Science.gov (United States)

    Speirs, Samantha; Yelland, Greg; Rinehart, Nicole; Tonge, Bruce

    2011-01-01

    The presence or absence of clinically delayed language development prior to 3 years of age is a key, but contentious, clinical feature distinguishing autism from Asperger's disorder. The aim of this study was to examine language processing in children with high-functioning autism (HFA) and Asperger's disorder (AD) using a task which taps lexical…

  14. Classroom Needs of Community College Students with Asperger's Disorder and Autism Spectrum Disorders

    Science.gov (United States)

    Gobbo, Ken; Shmulsky, Solvegi

    2012-01-01

    Community college students with Asperger's Disorder and Autism Spectrum Disorders can experience significant challenges from the social aspect of classroom learning and college life in comparison to their peers. This article explains unique challenges of postsecondary learners with Asperger's Disorder and Autism Spectrum Disorders. It also…

  15. Practitioner Views of Aspergers' Disorder: Clinical Diagnosis and Special Education Eligibility

    Science.gov (United States)

    Swisher, Arthur H., Jr.

    2009-01-01

    The purpose of this study was to investigate the perceptions of school psychology practitioners regarding Asperger's Disorder, focusing on practitioner perceptions of self-competence, conceptualization of the clinical characteristics of the disorder, and how Asperger's Disorder is conceptualized for the purpose of determining special education…

  16. Constructing Normalcy: A Qualitative Study of Parenting Children with Asperger's Disorder

    Science.gov (United States)

    Lasser, Jon; Corley, Kristyn

    2008-01-01

    Children with Asperger's Disorder present unique challenges due to their impairments in social functioning. In order to better understand the experiences of parents of children with Asperger's Disorder, interviews were conducted with 20 parents. The interviews were taped, transcribed, and coded using the systematic methods of Grounded Theory. The…

  17. The comparison of Wechsler intelligence test outcomes between children with Asperger syndrome and children with attention deficit hyperactivity disorder%Asperger综合征和注意缺陷多动障碍儿童的韦氏智商比较

    Institute of Scientific and Technical Information of China (English)

    岑超群; 邹园园; 陈凯云; 邓红珠; 邹小兵

    2015-01-01

    Objective To compare the intelligence quotient (IQ) between children with Asperger syndrome (AS) and children with attention deficit hyperactivity disorder (ADHD) in order to provide reliable evidence for differential diagnosis.Methods The intelligence of 141 children with AS,154 children with ADHD and 102 normal control (NC) children aged 6-13 years old examined by the China-Wechsler Intelligence Scale for Children was analyzed,and the diagnoses of AS and ADHD was made according to the Fourth edition of the Diagnostic and Statistical Manual of Mental Disorder.Results The proportions of children at low level of IQ (borderline and mental retardation range) in children with AS and with ADHD group were both significantly higher than those of NC group.The proportions of children at top level of IQ (superior and very superior range) in ADHD group were significantly lower than those of AS and NC groups.In the AS group,higher proportions of verbal IQ (VIQ) at top level and performance IQ (PIQ) at low level were found.The average VIQ,PIQ and full IQ (FIQ) of the AS,ADHD and NC groups were (102.55 ± 17.27,91.31 ± 16.01,97.10 ± 15.88),(95.39 ±13.49,94.16 ± 12.92,94.40 ± 12.78) and (104.06 ± 13.66,103.05 ±11.80,103.91 ± 12.92),respectively.The VIQ,PIQ and FIQ in ADHD group were lower than those in NC group significantly(P < 0.01);compared with NC group,the PIQ and FIQ in AS group were significantly lower (P < 0.01),while the VIQ was not significantly different(P >0.05).The AS and ADHD group scored both lower than the NC groupin the subtests of " comprehension"," coding"," picture completion" and " picture arrangement" (P < 0.01).The difference values between VIQ and PIQ in the AS,ADHD and TD group were(11.23 ± 17.29),(1.23 ± 13.10) and (1.00 ± 10.91),respectively,among which only the value in AS group was statistically significant (P < 0.01) but not in ADHD and NC group(P >0.05).The proportion of children having a VIQ-PIQ difference value more than 15

  18. Disordered recognition of facial identity and emotions in three Asperger type autists.

    Science.gov (United States)

    Njiokiktjien, C; Verschoor, A; de Sonneville, L; Huyser, C; Op het Veld, V; Toorenaar, N

    2001-03-01

    In this report we aim to explore severe deficits in facial affect recognition in three boys all of whom meet the criteria of Asperger's syndrome (AS), as well as overt prosopagnosia in one (B) and covert prosopagnosia in the remaining two (C and D). Subject B, with a familially-based talent of being highly gifted in physics and mathematics, showed no interest in people, a quasi complete lack of comprehension of emotions, and very poor emotional reactivity. The marked neuropsychological deficits were a moderate prosopagnosia and severely disordered recognition of facial emotions, gender and age. Expressive facial emotion, whole body psychomotor expression and speech prosody were quasi absent as well. In all three boys these facial processing deficits were more or less isolated, and general visuospatial functions, attention, formal language and scholastic performances were normal or even highly developed with the exception of deficient gestalt perception in B. We consider the deficient facial emotion perception as an important pathogenetic symptom for the autistic behaviour in the three boys. Prosopagnosia, the absent facial and bodily expression, and speech prosody were important but varying co-morbid disorders. The total clinical picture of non-verbal disordered communication is a complex of predominantly bilateral and/or right hemisphere cortical deficits. Moreover, in B, insensitivity to pain, smells, noises and internal bodily feelings suggested a more general emotional anaesthesia and/or a deficient means of expression. It is possible that a limbic component might be involved, thus making affective appreciation also deficient. PMID:11315539

  19. The role of experience in teachers’ social representation of students with autism spectrum diagnosis (Asperger

    Directory of Open Access Journals (Sweden)

    Ann-Charlotte Linton

    2015-12-01

    Full Text Available Support from teachers is a key strategy for accommodating students with Asperger syndrome (AS diagnosis in the mainstream classroom. Teachers’ understanding and expectations of students, i.e. their social representations (SR, have a bearing on how they interact and accommodate, but little is known about why. Therefore, the current study examined the idea that teachers’ SR of these students are influenced by their previous experience with AS. To this end, Swedish mainstream teachers were invited to anonymously answer a web-based questionnaire (N = 153. An association task was used to obtain data on teachers’ SR and the content and structure of the SR were explored. Our results suggest that work-related experience of AS and/or private experience shape teachers’ SR of these students relative to teachers with no experience. Moreover, teachers with previous experience had more SR elements related to environment and learning factors while teachers without previous experience had more elements related to the individual’s behavior. Teachers with private experience produced fewer positive elements compared to those with work-related experience only. These results highlight the role of contextual factors and prior experience in forming SR. We conclude that contact with students with AS, e.g. during teacher training, could facilitate accommodation in mainstream schools.

  20. Cognitive profiles and regional cerebral blood flow changes in individuals with Asperger's disorder and Schizophrenia

    International Nuclear Information System (INIS)

    Described are differences of the profiles and blood flow (CBF) changes in the title between individuals with Asperger's disorder (AD) and Schizophrenia (SZ). Children with AD syndrome have been suggested to have reasoning and fluid intelligence superior to normally developed ones, and to be of cognitive disability for the spatial composition which is thought to reflect the impairment in the right hemisphere. These characteristics are not suggested in SZ. Presented are examinations by authors of 99m ethyl cysteinate dimer (ECD)-single photon emission computed tomography (SPECT) images with Patlak method of 7 AD males (average age 24.4 y), 4 AD females (25.5 y), and 4 males and 2 females with SZ (25.8 y). Image analysis is done by SPM99 (Statistical Parametric Mapping) with standardized brain. Control with the matched age and sex is obtained from database of the normal healthy ones. In AD, clearly lowered CBF is observed in the right lateral and medial parietal lobe and right superior temporal convolution (particularly, in females), and in SZ, in the dorsolateral and dorsomedial regions of frontal lobe of both sides. The finding in the right superior temporal convolution in AD is considered to be important from the aspect of impairment of eye gaze processing. (R.T.)

  1. O autoconceito em jovens com Síndrome de Asperger

    OpenAIRE

    Rodrigues, Ana Rita Janela de Araújo

    2013-01-01

    A Síndrome de Asperger é uma perturbação do Espectro do Autismo que interfere consideravelmente na interação social. Considerando o autoconceito um constructo de elevada importância para a formação da personalidade e que interfere no relacionamento com os outros, é imperioso fomentar estratégias de modo a possibilitar a aquisição de um autoconceito mais positivo. O presente estudo visa conhecer o perfil de Autoconceito de três jovens com idades compreendidas entre os 10 e os...

  2. Multidisciplinary treatment of tooth wear in a patient with Asperger’s Syndrome and dental anxiety

    NARCIS (Netherlands)

    P. Wetselaar; J.H. Vermaire; F. Lobbezoo

    2013-01-01

    This case report describes a patient who is referred by his home physician to a centre for special dental care because of the presence of severe oral pain with an existing dental phobia. The patient has Asperger's Syndrome. Besides his extreme fear for dental treatment and several deep carious lesio

  3. Cognitive Processes in ADHD and Asperger's Disorder: Overlaps and Differences in PASS Profiles.

    Science.gov (United States)

    Taddei, Stefano; Contena, Bastianina

    2013-11-01

    Objective: Many studies report on the usefulness of the evaluation of Executive Functions (EF) in the assessment of participants with ADHD, while others underline how deficits of EF in these participants are not consistent and that the same executive deficits are present in many other disorders, particularly in Asperger's disorder. Using the Planning Attention Simultaneous Successive (PASS) theory, the present study explores the cognitive profiles of participants with ADHD or Asperger's disorder and compares the cognitive functioning of these two diagnostic groups. Method: Forty-four children, 24 with a diagnosis of ADHD and 20 with a diagnosis of Asperger's disorder, participated and their cognitive processes were evaluated with the Cognitive Assessment System. Results: Results underline specific cognitive profiles in ADHD and Asperger's disorder characterized by weaknesses in planning and attention, but with a diverse level of severity. Conclusion: Implications of the different cognitive profiles of these diagnostic groups are discussed. (J. of Att. Dis. 2013; XX(X) 1-XX). PMID:24196344

  4. Deficient saccadic inhibition in Asperger's disorder and the social-emotional processing disorder

    OpenAIRE

    Manoach, D; Lindgren, K.; Barton, J.

    2004-01-01

    Background: Both Asperger's disorder and the social-emotional processing disorder (SEPD), a form of non-verbal learning disability, are associated with executive function deficits. SEPD has been shown to be associated with deficient saccadic inhibition.

  5. Asperger through the Looking Glass: An Exploratory Study of Self-Understanding in People with Asperger's Syndrome

    Science.gov (United States)

    Jackson, Paul; Skirrow, Paul; Hare, Dougal Julian

    2012-01-01

    Hobson (Autism and the development of mind. Lawrence Erlbaum, Hove, UK "1993") has proposed that the cognitive and linguistic disabilities that characterise autism result from abnormalities in inter-subjective engagement during infancy, which in turn results in impaired reflective self-awareness. The aim of the present study was to test Hobson's…

  6. Síndrome de Asperger: relato de um caso

    Directory of Open Access Journals (Sweden)

    Letícia Viana Pereira

    2012-04-01

    Full Text Available Objetivo: O presente estudo tem como real objetivo o relato de um caso de Síndrome de Asperger comprado às características descritas na literatura. Metodologia: A partir de um relato de um caso atendido na Clínica Escola de Fonoaudiologia do Centro Universitário Metodista Izabela Hendrix, determinadas características foram comparadas com o descrito na literatura pertinente. Os trabalhos foram lidos, fichados e agrupados, segundos algumas características de abordagem, para posterior análise e comparação com o caso clínico relatado. Discussão e resultados: As crianças com Síndrome de Asperger são, em geral, diferentes entre si. Freqüentemente procedimentos realizados que podem ser indicados para uma criança seriam inadequados para outra. Assim, sugestões apresentadas pela literatura devem ser consideradas para melhorar a assistência à criança, como a compreensão mais abrangente e a reflexão aprofundada em relação a cada caso em específico. Conclusão: O acompanhamento e tratamento fonoaudiológico nesses casos, é de suma importância para o desenvolvimento o mais próximo possível do considerado formal na linguagem e na comunicação destes indivíduos. Vivências clínicas mostram as estratégias que podem ser sugeridas para estas crianças, lembrando que casa criança possui suas particularidades, que devem sempre ser levadas em consideração.

  7. A Preliminary Transcranial Magnetic Stimulation Study of Cortical Inhibition and Excitability in High-Functioning Autism and Asperger Disorder

    Science.gov (United States)

    Enticott, Peter G.; Rinehart, Nicole J.; Tonge, Bruce J.; Bradshaw, John L.; Fitzgerald, Paul B.

    2010-01-01

    Aim: Controversy surrounds the distinction between high-functioning autism (HFA) and Asperger disorder, but motor abnormalities are associated features of both conditions. This study examined motor cortical inhibition and excitability in HFA and Asperger disorder using transcranial magnetic stimulation (TMS). Method: Participants were diagnosed by…

  8. Views on the Diagnostic Labels of Autism and Asperger's Disorder and the Proposed Changes in the DSM

    Science.gov (United States)

    Kite, Donna M.; Gullifer, Judith; Tyson, Graham A.

    2013-01-01

    With the approaching release of the DSM V in 2013, there has been much debate about the proposal to remove the diagnostic label of Asperger's disorder from the new DSM. This study explored how health and education professionals perceive the conditions of autism and Asperger's disorder and their views on the proposed diagnostic changes.…

  9. Task Dependent Prefrontal Dysfunction in Persons with Asperger's Disorder Investigated with Multi-Channel Near-Infrared Spectroscopy

    Science.gov (United States)

    Iwanami, Akira; Okajima, Yuka; Ota, Haruhisa; Tani, Masayuki; Yamada, Takashi; Hashimoro, Ryuichiro; Kanai, Chieko; Watanabe, Hiromi; Yamasue, Hidenori; Kawakubo, Yuki; Kato, Nobumasa

    2011-01-01

    Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder…

  10. How Well Can Young People with Asperger's Disorder Recognize Threat and Learn about Affect in Faces?: A Pilot Study

    Science.gov (United States)

    Miyahara, Motohide; Ruffman, Ted; Fujita, Chikako; Tsujii, Masatsugu

    2010-01-01

    The abilities to identify threat and learn about affect in facial photographs were compared between a non-autistic university student group (NUS), a matched Asperger's group (MAS) on the Standard Progressive Matrices (SPM), and an unmatched Asperger's group (UAS) who scored lower on the SPM. Participants were given pairs of faces and asked which…

  11. Reaction Time of Facial Affect Recognition in Asperger's Disorder for Cartoon and Real, Static and Moving Faces

    Science.gov (United States)

    Miyahara, Motohide; Bray, Anne; Tsujii, Masatsugu; Fujita, Chikako; Sugiyama, Toshiro

    2007-01-01

    This study used a choice reaction-time paradigm to test the perceived impairment of facial affect recognition in Asperger's disorder. Twenty teenagers with Asperger's disorder and 20 controls were compared with respect to the latency and accuracy of response to happy or disgusted facial expressions, presented in cartoon or real images and in…

  12. Individuals with Asperger's Disorder Exhibit Difficulty in Switching Attention from a Local Level to a Global Level

    Science.gov (United States)

    Katagiri, Masatoshi; Kasai, Tetsuko; Kamio, Yoko; Murohashi, Harumitsu

    2013-01-01

    The purpose of the present study was to determine whether individuals with Asperger's disorder exhibit difficulty in switching attention from a local level to a global level. Eleven participants with Asperger's disorder and 11 age- and gender-matched healthy controls performed a level-repetition switching task using Navon-type hierarchical…

  13. Normal P50 gating in children with autism, yet attenuated P50 amplitude in the Asperger subcategory

    DEFF Research Database (Denmark)

    Madsen, Gitte; Bilenberg, Niels; Jepsen, Jens Richardt Møllegaard;

    2015-01-01

    the Asperger subgroup compared to healthy controls. In contrast to what is usually reported for patients with schizophrenia, we found no evidence for sensory gating deficits in our group of ASD children taken as a whole. However, reduced P50 amplitude to conditioning stimuli was found in the Asperger...

  14. A Comparative Study of the Spontaneous Social Interactions of Children with High-Functioning Autism and Children with Asperger's Disorder

    Science.gov (United States)

    Macintosh, Kathleen; Dissanayake, Cheryl

    2006-01-01

    A comparative observational study was undertaken of the spontaneous social interactions of children with high-functioning autism and Asperger's disorder. The sample comprised 20 children with high-functioning autism, 19 children with Asperger's disorder and 17 typically developing children matched on chronological age and overall mental age. A…

  15. Social Skills and Problem Behaviours in School Aged Children with High-Functioning Autism and Asperger's Disorder

    Science.gov (United States)

    Macintosh, Kathleen; Dissanayake, Cheryl

    2006-01-01

    The social skills and problem behaviours of children with high-functioning autism and Asperger's Disorder were compared using parent and teacher reports on the Social Skills Rating System. The participants were 20 children with high-functioning autism, 19 children with Asperger's Disorder, and 17 typically developing children, matched on…

  16. Falsos mitos sobre el Sindrome de Asperger en los medios de comunicación

    OpenAIRE

    Moreno Antequera, Dolores; Cano Bravo, Fátima; Martín Pérez, Ana Cristina

    2015-01-01

    Introducción: Los medios de comunicación vierten constantemente informaciones erróneas así como versiones distorsionadas del Síndrome de Asperger. Objetivo: desmitificar los falsos mitos que giran en torno al mismo y por tanto dar a conocer la realidad de las personas con Síndrome de Asperger. Metodología: Se trata de un estudio descriptivo longitudinal. La muestra estuvo constituida por la revisión bibliográfica en base dato...

  17. Asperger's综合征1例临床分析

    Institute of Scientific and Technical Information of China (English)

    白杰

    2008-01-01

    @@ 广泛性发育障碍是一种以明显的社会和沟通技能缺陷及刻板的兴趣和行为模式为特征的儿童精神疾病,主要包括婴儿孤独症、Asperger's综合征、Rett's综合征、婴儿痴呆.我科于2007年接诊一名患儿,经南京脑科医院诊断为Asperger's综合征,现报告如下:

  18. Abnormalities of Quantitative Electroencephalography in Children with Asperger Disorder Using Spectrogram andCoherence Values

    OpenAIRE

    Hamid Behnam; Ali Sheikhani; Maryam Noroozian; Mohammad Reza Mohammadi

    2008-01-01

    "n  "n  "nObjective:To obtain abnormalities in quantitative Electroencephalography QEEG) and to observe connectivity between electrodes in children with Asperger disorder. "n  "n  "nMethod: "nIn this study, spectrogram criteria and coherence values are used as a tool for evaluating QEEG in 15 children with Asperger disorder (10 boys and 5 girls aged between 6 to 11 years old) and in 11 control children boys and 4 girls with the same age range). "n  "n  "nResults:...

  19. Omasta hygieniASta : Ohjeistus henkilökohtaisesta hygieniasta huolehtimiseen Asperger-nuorille

    OpenAIRE

    Lappalainen, Jonna

    2013-01-01

    Opinnäytetyönäni tein ohjeistuksen Asperger-nuorille henkilökohtaisen hygienian hoitamisen tueksi. Opinnäytetyöni on toiminnallinen opinnäytetyö, jonka tavoitteena on ohjata henkilökohtaisen hygienian hoitoon liittyvien toimintojen ylläpitämisessä. Tavoitteena oli luoda materiaalia, jota voidaan muokata nuoren yksilöllisten tarpeiden mukaan. Asperger-nuorten kohdalla hygienian hoitamiseen heijastuu oireyhtymään liittyvien ominaisuuksien johdosta erityisiä haasteita. Ohjeistuksessa on läh...

  20. Views on the diagnostic labels of autism and Asperger's disorder and the proposed changes in the DSM.

    Science.gov (United States)

    Kite, Donna M; Gullifer, Judith; Tyson, Graham A

    2013-07-01

    With the approaching release of the DSM V in 2013, there has been much debate about the proposal to remove the diagnostic label of Asperger's disorder from the new DSM. This study explored how health and education professionals perceive the conditions of autism and Asperger's disorder and their views on the proposed diagnostic changes. Analysis of the 547 participant responses confirmed an increase stigma is associated with the label of autism, with autism considered to be a more severe than the condition of Asperger's disorder. Approximately half of the participants reported being opposed to proposed diagnostic changes and of the remaining participants, 22% supported the proposed changes and 28% expressed uncertainty. PMID:23143130

  1. The Relationship of Asperger's Characteristics and Schizotypal Personality Traits in a Non-Clinical Adult Sample

    Science.gov (United States)

    Hurst, Ruth M.; Nelson-Gray, Rosemery O.; Mitchell, John T.; Kwapil, Thomas R.

    2007-01-01

    The study examines the relationship between Asperger's Disorder (AD) and Schizotypal Personality Disorder (SPD), mutually exclusive but similar diagnoses ["DSM-IV-TR;" American Psychiatric Association (2000). "Diagnostic and statistical manual of mental disorders." Washington, DC: Author]. The literature and comparison of diagnostic criteria…

  2. Diagnostic Assessment of Asperger's Disorder: A Review of Five Third-Party Rating Scales

    Science.gov (United States)

    Campbell, Jonathan M.

    2005-01-01

    Five rating scales for screening and detection of Asperger's Disorder, three commercially available and two research instruments, are evaluated with reference to psychometric criteria outlined by Bracken in 1987 ("Journal of Psychoeducational Assessment," 4, 313). Reliability and validity data reported in examiner's manuals or published reports…

  3. Comparing Neuropsychological Profiles between Girls with Asperger's Disorder and Girls with Learning Disabilities

    Science.gov (United States)

    McKnight, Megan E.; Culotta, Vincent P.

    2012-01-01

    Research examining neuropsychological profiles of girls with Asperger's disorder (AD) is sparse. In this study, we sought to characterize neurocognitive profiles of girls with AD compared to girls with learning disabilities (LD). Two groups of school-age girls referred for neuropsychological assessment participated in the study. A total of 23…

  4. Dynamic Fearful Gaze Does Not Enhance Attention Orienting in Individuals with Asperger's Disorder

    Science.gov (United States)

    Uono, Shota; Sato, Wataru; Toichi, Motomi

    2009-01-01

    Although impaired joint attention is one of the core clinical features of pervasive developmental disorder including autistic disorder and Asperger's disorder, experimental studies failed to report its impairment. This discrepancy might be the result of differences between real-life and experimental situations. The present study examined joint…

  5. Differentiation of High-Functioning Autism and Asperger's Disorder Based on Neuromotor Behaviour

    Science.gov (United States)

    Nayate, Ashwini; Tonge, Bruce J.; Bradshaw, John L.; McGinley, Jennifer L.; Iansek, Robert; Rinehart, Nicole J.

    2012-01-01

    Autism and Asperger's disorder (AD) are characterised by impairments in social interaction, stereotypic behaviours or restricted interests. Although currently listed as distinct clinical disorders, the validity of their distinction remains controversial. This study examined gait in children with autism and AD. Eleven children with high-functioning…

  6. Brief Report: Abnormal Association between the Thalamus and Brain Size in Asperger's Disorder

    Science.gov (United States)

    Hardan, Antonio Y.; Girgis, Ragy R.; Adams, Jason; Gilbert, Andrew R.; Melhem, Nadine M.; Keshavan, Matcheri S.; Minshew, Nancy J.

    2008-01-01

    The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger's disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10-35 years) and 12 healthy controls (age range: 9-33 years). A positive correlation…

  7. A Deficit in Shifting Attention Present in High-Functioning Autism but Not Asperger's Disorder.

    Science.gov (United States)

    Rinehart, Nicole J.; Bradshaw, John L.; Moss, Simon A.; Brereton, Avril V.; Tonge, Bruce J.

    2001-01-01

    A study examined the executive functioning, in particular the attentional set-shifting deficits in Australian individuals ages 6-20 with high-functioning autism (n=12) and Asperger's disorder (n=12). Results indicate that individuals with autism had a deficiency in shifting from local to global processing, however, this was not observed in…

  8. Delayed Video Self-Recognition in Children with High Vo Functioning Autism and Asperger's Disorder

    Science.gov (United States)

    Dissanayake, Cheryl; Shembrey, Joh; Suddendorf, Thomas

    2010-01-01

    Two studies are reported which investigate delayed video self-recognition (DSR) in children with autistic disorder and Asperger's disorder relative to one another and to their typically developing peers. A secondary aim was to establish whether DSR ability is dependent on metarepresentational ability. Children's verbal and affective responses to…

  9. Attentional Blink in Young People with High-Functioning Autism and Asperger's Disorder

    Science.gov (United States)

    Rinehart, Nicole; Tonge, Bruce; Brereton, Avril; Bradshaw, John

    2010-01-01

    The aim of the study was to examine the temporal characteristics of information processing in individuals with high-functioning autism and Asperger's disorder using a rapid serial visual presentation paradigm. The results clearly showed that such people demonstrate an attentional blink of similar magnitude to comparison groups. This supports the…

  10. Brief Report: Inhibition of Return in Young People with Autism and Asperger's Disorder

    Science.gov (United States)

    Rinehart, Nicole J.; Bradshaw, John L.; Moss, Simon A.; Brereton, Avril V.; Tonge, Bruce J.

    2008-01-01

    The aim of this study was to investigate whether the superior search abilities observed in autism/Asperger's disorder may in part be a consequence of a more pronounced inhibition of return (IOR). Contrary to our prediction, IOR in individuals with autism was comparable to the matched comparison group. However, the autism group committed more false…

  11. Impairment of Unconscious, but Not Conscious, Gaze-Triggered Attention Orienting in Asperger's Disorder

    Science.gov (United States)

    Sato, Wataru; Uono, Shota; Okada, Takashi; Toichi, Motomi

    2010-01-01

    Impairment of joint attention represents the core clinical features of pervasive developmental disorders (PDDs), including autism and Asperger's disorder. However, experimental studies reported intact gaze-triggered attentional orienting in PDD. Since all previous studies employed supraliminal presentation of gaze stimuli, we hypothesized that…

  12. Brief Report: Biochemical Correlates of Clinical Impairment in High Functioning Autism and Asperger's Disorder

    Science.gov (United States)

    Kleinhans, Natalia M.; Richards, Todd; Weaver, Kurt E.; Liang, Olivia; Dawson, Geraldine; Aylward, Elizabeth

    2009-01-01

    Amygdala dysfunction has been proposed as a critical contributor to social impairment in autism spectrum disorders (ASD). The current study investigated biochemical abnormalities in the amygdala in 20 high functioning adults with autistic disorder or Asperger's disorder and 19 typically developing adults matched on age and IQ. Magnetic resonance…

  13. High-Functioning Autism and Asperger's Disorder: Utility and Meaning for Families

    Science.gov (United States)

    Ruiz Calzada, Luisa; Pistrang, Nancy; Mandy, William P. L.

    2012-01-01

    We used framework analysis to investigate the utility of pervasive developmental disorder diagnoses, interviewing young people (aged 9-16 years) with high-functioning autistic disorder (AD) and Asperger's disorder (AsD), and their parents. Twenty two participants from ten families described both gains and costs resulting from diagnosis. Perceived…

  14. The Impact of Labels and Behaviors on the Stigmatization of Adults with Asperger's Disorder

    Science.gov (United States)

    Butler, Robert C.; Gillis, Jennifer M.

    2011-01-01

    Currently, there is a paucity of literature on stigmatization of adults with Asperger's Disorder (AD). Therefore, this study examined whether young adults hold stigmatizing views towards individuals with AD and if that stigmatization is elicited by behaviors or labels. College students (N = 195) read one of six vignettes. A modified Social…

  15. Intervenções terapêuticas em portadores da Síndrome de Asperger: revisão da literatura

    Directory of Open Access Journals (Sweden)

    Marília Consolini Teodoro

    2013-01-01

    Full Text Available A Síndrome de Asperger (SA é um dos diagnósticos pertencentes ao Grupo dos Transtornos Globais do Desenvolvimento, do qual também faz parte o autismo. A SA tem como características os interesses restritos e as dificuldades na interação social. Ao contrário do autismo, não há deficiência da linguagem. Este estudo teve por objetivo apresentar uma revisão da literatura científica nacional acerca da Síndrome de Asperger, com ênfase nas intervenções terapêuticas desenvolvidas no contexto brasileiro. Foram recuperados dez artigos nas bases LILACS, SciELO e PePSIC, no período de 2001 a 2011. A maior parte dos estudos é de caráter empírico. As intervenções são predominantemente apresentadas pela Fonoaudiologia, devido às características que o portador apresenta referentes aos prejuízos na interação e nas habilidades de comunicação, mesmo que não existam as dificuldades na linguagem em si. De modo geral, constatou-se que as intervenções terapêuticas aplicadas aos portadores da SA têm efeitos positivos e acarretam mudanças de comportamento e melhor qualidade de vida ao portador, além de ser observado que o trabalho terapêutico associado à intervenção com a família tende a garantir maiores benefícios a ambos. Abstract This study aimed at reviewing of a Brazilian scientific literature about the Asperger's Syndrome (AS, with emphasis on therapeutic interventions developed in the Brazilian context. Ten articles published between 2001 and 2011 were recovered at LILACS, SciELO and PePSIC. Most of these studies are empirical. Interventions are predominantly made by Speech-Language Therapy, due to the characteristics that the bearer has related to losses in interaction and communication skills. Overall, it was found that the therapeutic interventions applied to patients with AS have positive effects and cause changes in behavior and improved the quality life, and can be observed that the therapeutic work associated

  16. 阿斯伯格症及高功能自闭症青少年社会技能干预的研究进展%An Overview of Researches into Social Skills-Based Intervention Towards Children with Asperger's Syndrome and High-Functioning Autism

    Institute of Scientific and Technical Information of China (English)

    魏然

    2013-01-01

    阿斯伯格症(Asperger’s syndrome,AS)和高功能自闭症(High-functioning autism,HFA)是自闭症研究领域中较为特殊的一部分,虽然其划分界限尚存在争议,但都具有包括社会技能缺乏在内的自闭症核心特征.本文回顾了近年来国外以AS或HFA青少年为对象的社会技能训练(social skills training,SST)项目文献,在总结针对自闭症患者的社会心理干预理想模式的基础上,将现有研究成果分为三类,即传统社会技能训练(Traditional social skills training,TSST)、认知行为方向的社会技能训练(Social skills training with cognitive behavioral orientation,SST-CB)和包含父母参与的社会技能训练(social skills training with additional parents component,SST-PC).文章还讨论了现有研究的局限性和未来的研究方向.

  17. The effects of context processing on social cognition impairments in adults with Asperger’s syndrome

    OpenAIRE

    Agustin Ibanez

    2014-01-01

    Social cognition—the basis of all communicative and otherwise interpersonal relationships—is embedded in specific contextual circumstances which shape intrinsic meanings. This domain is compromised in the autism spectrum disorders (ASDs), including Asperger's syndrome (AS) (DSM-V). However, the few available reports of social cognition skills in adults with AS have largely neglected the effects of contextual factors. Moreover, previous studies on this population have also failed to simultaneo...

  18. Wellness Interventions for School Counselors: A Case-Study in Treating Asperger's Disorder

    Science.gov (United States)

    Hartwig Moorhead, Holly J.; Green, Judy; McQuistion, Rick R.; Ozimek, Barbara

    2008-01-01

    The Five Factor Wellness Inventory-Elementary Version (5F-WEL -E) was used in a pre- and post-test design to determine the wellness of a 13 year-old male with Asperger's Disorder. Wellness in the Creative and Physical Self domains was low. Thus, the school counselor implemented a 5-month treatment plan, based upon the Wheel of Wellness, in the…

  19. Asperger disorder and the Tomatis method : a case-study / Lindi Nel

    OpenAIRE

    Nel, Lindi

    2005-01-01

    This study aimed to determine what the effect of participation in a Tomatis Programme (TP) would be on the psychological well-being and communication ability of a 14 year old, white adolescent boy with Asperger Disorder (AD). A mixed method design in the form of a single casestudy was used. Qualitative data were obtained via semi-s!mctured interviews, spontaneous sketches and observation. Quantitative data were gathered by means of projective drawings and the Profile of Mood...

  20. Brief Report: The Impact of Changing from DSM-IV "Asperger's" to DSM-5 "Autistic Spectrum Disorder" Diagnostic Labels on Stigma and Treatment Attitudes

    Science.gov (United States)

    Ohan, Jeneva L.; Ellefson, Sarah E.; Corrigan, Patrick W.

    2015-01-01

    In the DSM-5, "Asperger's Disorder" was incorporated into "Autistic Spectrum Disorder" (ASD). One key concern in this change has been that the ASD label will increase negative attitudes relative to the Asperger's label. To test this, we asked 465 American adults to read a vignette describing a child with autistic symptoms that…

  1. Savant syndrome: realities, myths and misconceptions.

    Science.gov (United States)

    Treffert, Darold A

    2014-03-01

    It was 126 years ago that Down first described savant syndrome as a specific condition and 70 years ago that Kanner first described Early Infantile Autism. While as many as one in ten autistic persons have savant abilities, such special skills occur in other CNS conditions as well such that approximately 50 % of cases of savant syndrome have autism as the underlying developmental disability and 50 % are associated with other disabilities. This paper sorts out realities from myths and misconceptions about both savant syndrome and autism spectrum disorders (ASD) that have developed through the years. The reality is that low IQ is not necessarily an accompaniment of savant syndrome; in some cases IQ can be superior. Also, savants can be creative, rather than just duplicative, and the skills increase over time on a continuum from duplication, to improvisation to creation, rather than diminishing or suddenly disappearing. Genius and prodigy exist separate from savant syndrome and not all such highly gifted persons have Asperger's Disorder. This paper also emphasizes the critical importance of separating 'autistic-like' symptoms from ASD especially in children when the savant ability presents as hyperlexia (children who read early) or as Einstein syndrome (children who speak late), or have impaired vision (Blindisms) because prognosis and outcome are very different when that careful distinction is made. In those cases the term 'outgrowing autism' might be mistakenly applied when in fact the child did not have ASD in the first place. PMID:23918440

  2. The neuropsychology of male adults with high-functioning autism or Asperger syndrome

    NARCIS (Netherlands)

    C.E. Wilson; F. Happé; S.J. Wheelwright; C. Ecker; M.V. Lombardo; P. Johnston; E. Daly; C.M. Murphy; D. Spain; M-C. Lai; B Chakrabarti; D.A. Sauter; - MRC AIMS Consortium; S. Baron-Cohen; D.G.M. Murphy

    2014-01-01

    Autism Spectrum Disorder (ASD) is diagnosed on the basis of behavioral symptoms, but cognitive abilities may also be useful in characterizing individuals with ASD. One hundred seventy-eight high-functioning male adults, half with ASD and half without, completed tasks assessing IQ, a broad range of c

  3. Eye-Witness Memory and Suggestibility in Children with Asperger Syndrome

    Science.gov (United States)

    McCrory, Eamon; Henry, Lucy A.; Happe, Francesca

    2007-01-01

    Background: Individuals with autism spectrum disorders (ASD) present with a particular profile of memory deficits, executive dysfunction and impaired social interaction that may raise concerns about their recall and reliability in forensic and legal contexts. Extant studies of memory shed limited light on this issue as they involved either…

  4. An Investigation into Social Information Processing in Young People with Asperger Syndrome

    Science.gov (United States)

    Flood, Andrea Mary; Hare, Dougal Julian; Wallis, Paul

    2011-01-01

    Deficits in social functioning are a core feature of autistic spectrum disorders (ASD), being linked to various cognitive and developmental factors, but there has been little attempt to draw on normative models of social cognition to understand social behaviour in ASD. The current study explored the utility of Crick and Dodge's (1994) information…

  5. Incidental diagnosis of HLRCC following investigation for Asperger Syndrome: actionable and actioned.

    Science.gov (United States)

    Duong, Bich-Thu; Savarirayan, Ravi; Winship, Ingrid

    2016-01-01

    Incidental findings are inevitable as clinical research and practice transitions from a single gene approach to a genomic approach. A novel deletion of the Fumarate Hydratase (FH) gene was identified in a 22 year old male who underwent a molecular karyotype as part of an autism spectrum disorder research project. This unexpected result implies a predisposition to Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC), a rare, autosomal dominant condition and has unforeseen implications for him and his family. We review the typical features and management of HLRCC and discuss the challenges that face health professionals, as genetic testing advances and becomes more accessible. PMID:26275867

  6. Errorless Compliance Training: Success-Focused Behavioral Treatment of Children with Asperger Syndrome

    Science.gov (United States)

    Ducharme, Joseph M.; Sanjuan, Elena; Drain, Tammy

    2007-01-01

    Errorless compliance training is a noncoercive, success-focused approach to treatment of problem behavior in children. The intervention involves graduated exposure of a child to increasingly more challenging requests at a slow enough rate to ensure that noncompliance rarely occurs, providing parents with many opportunities to reinforce cooperative…

  7. Spatial Frequency and Face Processing in Children with Autism and Asperger Syndrome

    Science.gov (United States)

    Deruelle, Christine; Rondan, Cecilie; Gepner, Bruno; Tardif, Carole

    2004-01-01

    Two experiments were designed to investigate possible abnormal face processing strategies in children with autistic spectrum disorders. A group of 11 children with autism was compared to two groups of normally developing children matched on verbal mental age and on chronological age. In the first experiment, participants had to recognize faces on…

  8. Enhanced Pure-Tone Pitch Discrimination among Persons with Autism but not Asperger Syndrome

    Science.gov (United States)

    Bonnel, Anna; McAdams, Stephen; Smith, Bennett; Berthiaume, Claude; Bertone, Armando; Ciocca, Valter; Burack, Jacob A.; Mottron, Laurent

    2010-01-01

    Persons with Autism spectrum disorders (ASD) display atypical perceptual processing in visual and auditory tasks. In vision, Bertone, Mottron, Jelenic, and Faubert (2005) found that enhanced and diminished visual processing is linked to the level of neural complexity required to process stimuli, as proposed in the neural complexity hypothesis.…

  9. Cognitive profiles of adults with high functioning autism (HFA) and Asperger syndrome

    NARCIS (Netherlands)

    Spek, Antoinette Alida

    2010-01-01

    In this thesis the cognitive strengths and weaknesses have been examined. The results show impairment in advanced theory of mind. Furthermore, impairment was found in processing speed. The results pointed to strengths in detailed information processing. No impairment was found in executive functioni

  10. Evidence Suggesting the Existence of Asperger Syndrome in the Mid-1800s

    Science.gov (United States)

    Koegel, Ashley Kern

    2008-01-01

    Originally published in "Putnam's Monthly Magazine" in 1853, nearly a century before autism spectrum disorder (ASD) was formally recognized, Herman Melville's "Bartleby" is the naive tale of a nonconforming, socially awkward character. However, when placed into contemporary context, retrospective analysis indicates that Bartleby may in fact have…

  11. Abnormal auditory forward masking pattern in the brainstem response of individuals with Asperger syndrome

    OpenAIRE

    Nielzen, Soren

    2010-01-01

    Johan Källstrand1, Olle Olsson2, Sara Fristedt Nehlstedt1, Mia Ling Sköld1, Sören Nielzén21SensoDetect AB, Lund, Sweden; 2Department of Clinical Neuroscience, Section of Psychiatry, Lund University, Lund, SwedenAbstract: Abnormal auditory information processing has been reported in individuals with autism spectrum disorders (ASD). In the present study auditory processing was investigated by recording auditory brainstem responses (ABRs) elicited by forward...

  12. Asperger syndrome with comorbid emotional disorder--treatment with psychoanalytic psychotherapy

    OpenAIRE

    Mero, Mervi-Marja

    2002-01-01

    The purpose of psychoanalytic psychotherapy is to help the child to grow and develop normally. Children who are able to play, process their problems in the play. The therapist's role is to engage with the play and verbalize the emotions and the interactions demonstrated in it. This case-presentation illustrates how the child can express and work his inner fears and anxieties in play-situations with the therapist and shows how this interaction helps the child to develop and individuate. Childr...

  13. Social Anxiety in Parents of High-Functioning Children with Autism and Asperger Syndrome

    Science.gov (United States)

    Kuusikko-Gauffin, Sanna; Pollock-Wurman, Rachel; Mattila, Marja-Leena; Jussila, Katja; Ebeling, Hanna; Pauls, David; Moilanen, Irma

    2013-01-01

    We evaluated social anxiety (SA) symptoms in parents of children with autism spectrum disorders (ASDs; N = 131) and community parents (N = 597) using the Social Phobia and Anxiety Inventory (SPAI). SA was significantly more common in ASD than control mothers (15.6 vs. 6.7 %) and more equal between the ASD and control fathers (3.3 vs. 4.8 %). The…

  14. The "Dance" of Communication: Counseling Families and Children with Asperger's Syndrome

    Science.gov (United States)

    Lozzi-Toscano, Bettina

    2004-01-01

    Counselors are trained to deal with many issues within the realm of human experience; many specialize in helping families cope with a variety of internal and external stressors. However, counselors are seldom given all the tools to handle the myriad possible difficulties families may encounter. When counselors are asked to help families cope with…

  15. A different view on the checkerboard? Alterations in early and late visually evoked EEG potentials in Asperger observers.

    Directory of Open Access Journals (Sweden)

    Juergen Kornmeier

    Full Text Available BACKGROUND: Asperger Autism is a lifelong psychiatric condition with highly circumscribed interests and routines, problems in social cognition, verbal and nonverbal communication, and also perceptual abnormalities with sensory hypersensitivity. To objectify both lower-level visual and cognitive alterations we looked for differences in visual event-related potentials (EEG between Asperger observers and matched controls while they observed simple checkerboard stimuli. METHODS: In a balanced oddball paradigm checkerboards of two checksizes (0.6° and 1.2° were presented with different frequencies. Participants counted the occurrence times of the rare fine or rare coarse checkerboards in different experimental conditions. We focused on early visual ERP differences as a function of checkerboard size and the classical P3b ERP component as an indicator of cognitive processing. RESULTS: We found an early (100-200 ms after stimulus onset occipital ERP effect of checkerboard size (dominant spatial frequency. This effect was weaker in the Asperger than in the control observers. Further a typical parietal/central oddball-P3b occurred at 500 ms with the rare checkerboards. The P3b showed a right-hemispheric lateralization, which was more prominent in Asperger than in control observers. DISCUSSION: The difference in the early occipital ERP effect between the two groups may be a physiological marker of differences in the processing of small visual details in Asperger observers compared to normal controls. The stronger lateralization of the P3b in Asperger observers may indicate a stronger involvement of the right-hemispheric network of bottom-up attention. The lateralization of the P3b signal might be a compensatory consequence of the compromised early checksize effect. Higher-level analytical information processing units may need to compensate for difficulties in low-level signal analysis.

  16. Desarrollo de un sistema informático para ayudar a adultos con síndrome de Asperger

    OpenAIRE

    Almache Montoya, Jefferson; Armas Perona, Juan Luis; Salgado Iturrino, María

    2016-01-01

    Este proyecto presenta un sistema informático para ayudar a personas Asperger, que tienen problemas para recordar actividades y objetos básicos, y a sus profesores especialistas. Se ha decidido llamarlo AS (Asperger). Se compone de dos aplicaciones Android: la aplicación tutor y la aplicación usuario. La primera es para que los profesionales, desde su propia tablet, puedan centralizar y gestionar toda la información de sus alumnos creando tareas, retos y eventos específicos para cada uno. La ...

  17. 'DSM-V is taking away our identity': the reaction of the online community to the proposed changes in the diagnosis of Asperger's disorder.

    Science.gov (United States)

    Giles, David C

    2014-03-01

    This article considers the fate of Asperger's disorder in the light of proposals for the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) to collapse Asperger's disorder along with other pervasive developmental disorders into a general spectrum of autism. It is argued that a powerful lay and scientific culture has evolved around the concept of Asperger's disorder, which has found a particularly compelling voice over the last decade in the online Asperger community, with websites such as Wrong Planet recruiting tens of thousands of members. In order to assess the impact of these proposed changes on the online Asperger community, 19 threads on the topic of Diagnostic and Statistical Manual of Mental Disorders (5th ed.) are analysed according to the arguments that community members put forward in favour of, or in opposition to, the proposals. Many members embrace the notion of the spectrum and have already coined a new identity - 'spectrumite' - to adapt to the diagnostic shift. Others, however, are suspicious of the motives behind the absorption of Asperger's disorder, and potential threats to the provision of services as well as the strong 'aspie' identity that reflects the large literature and the online public sphere around Asperger's disorder. To what extent this culture poses a challenge to the authority of the Diagnostic and Statistical Manual of Mental Disorders is uncertain at present. PMID:23739773

  18. Abnormalities of Quantitative Electroencephalography in Children with Asperger Disorder Using Spectrogram andCoherence Values

    Directory of Open Access Journals (Sweden)

    Hamid Behnam

    2008-07-01

    Full Text Available "n  "n  "nObjective:To obtain abnormalities in quantitative Electroencephalography QEEG and to observe connectivity between electrodes in children with Asperger disorder. "n  "n  "nMethod: "nIn this study, spectrogram criteria and coherence values are used as a tool for evaluating QEEG in 15 children with Asperger disorder (10 boys and 5 girls aged between 6 to 11 years old and in 11 control children boys and 4 girls with the same age range. "n  "n  "nResults: "nThe evaluation of QEEG using statistical analysis and spectrogram criteria demonstrates that the relaxed eye-opened condition in gamma frequency band (34-44Hz has the best distinction level of 96.2% using spectrogram. The children with Asperger disorder had significant lower spectrogram criteria values (p<0.01 at Fp1 electrode and lower values (p<0.05 at Fp2 and T6 electrodes. Coherence values at 171 pairs EEG electrodes indicate that the connectivity at (T4, P4, (T4, Cz, (T4, C4 electrode pairs and (T4, O1 had significant differences (p<0.01 in the two groups in the gamma band. "n  "n  "nConclusions: "nIt is shown that gamma frequency band can discriminate 96.2% of the two groups using the spectrogram criteria. The results demonstrate that there are more abnormalities in the prefrontal and right temporal lobes using spectrogram criteria and there are more abnormalities "nthe connectivity of right temporal lobe with the other lobes in the gamma "nfrequency band.

  19. Programa de Habilidades Sociales para Trastornos del Espectro del Autismo en la Adolescencia: Trastorno de Asperger

    OpenAIRE

    Rodríguez Cuadrado, Beatriz

    2014-01-01

    A través de este trabajo de fin de máster, lo que se pretende es crear un programa de Habilidades Sociales para adolescentes con Trastorno de Asperger, uno de los Trastornos del Espectro del Autismo en el cual estas personas presentan dificultades en la interacción social, además de presentar pautas repetitivas y conductas estereotipadas. Este tipo de personas, por lo tanto, no son capaces de relacionarse y comunicarse de manera adecuada con los demás. Dirigido al colectivo adolescente par...

  20. El Arteterapia en niños con Síndrome de Asperger

    OpenAIRE

    Rodríguez-Pérez, Ana

    2013-01-01

    Este trabajo pretende acercar a sus lectores la realidad de los niños con síndrome de Asperger y el concepto de Arteterapia. Está estructurado en tres partes: la primera parte se trata de una breve introducción al concepto de Arteterapia (objetivos, dimensiones, técnicas…). La segunda comprende un pequeño estudio del síndrome, indispensable para saber a qué tipología de alumnos nos dirigimos. La última parte se trata de un supuesto práctico, un ejemplo de actividades para llevar a cabo en un ...

  1. Comparison of Scores on the Checklist for Autism Spectrum Disorder, Childhood Autism Rating Scale, and Gilliam Asperger's Disorder Scale for Children with Low Functioning Autism, High Functioning Autism, Asperger's Disorder, ADHD, and Typical Development

    Science.gov (United States)

    Mayes, Susan Dickerson; Calhoun, Susan L.; Murray, Michael J.; Morrow, Jill D.; Yurich, Kirsten K. L.; Mahr, Fauzia; Cothren, Shiyoko; Purichia, Heather; Bouder, James N.; Petersen, Christopher

    2009-01-01

    Reliability and validity for three autism instruments were compared for 190 children with low functioning autism (LFA), 190 children with high functioning autism or Asperger's disorder (HFA), 76 children with attention deficit hyperactivity disorder (ADHD), and 64 typical children. The instruments were the Checklist for Autism Spectrum Disorder…

  2. Beals Syndrome

    Science.gov (United States)

    ... Boards & Staff Annual Report & Financials Contact Us Donate Marfan & Related Disorders What is Marfan Syndrome? What are ... the syndrome. How does Beals syndrome compare with Marfan syndrome? People with Beals syndrome have many of ...

  3. Annotation: The Similarities and Differences between Autistic Disorder and Asperger's Disorder--A Review of the Empirical Evidence

    Science.gov (United States)

    Macintosh, Kathleen E.; Dissanayake, Cheryl

    2004-01-01

    Background: The ongoing controversy over the distinction between autistic disorder and Asperger's disorder is important to resolve because of the implications regarding an understanding of the aetiology and prognosis, and the diagnostic and clinical practices relating to these conditions. This paper provides a critical evaluation of current…

  4. Diabetes Insipidus and Polydipsia in a Patient with Asperger's Disorder and an Empty Sella: A Case Report.

    Science.gov (United States)

    Raja, Michele; Azzoni, Antonella; Giammarco, Vincenzo

    1998-01-01

    Describes an Italian patient with Asperger disorders, Neurogenic Diabetes Insipidus, and Primary Empty Sella. His response to vasopressin treatment suggested a concomitant presence of primary polydipsia. Implications of the observed concurrence of these rare disorders are discussed in relation to diagnosis and pathogenesis. (Author/CR)

  5. Common and Unique Impairments in Facial-Expression Recognition in Pervasive Developmental Disorder-Not Otherwise Specified and Asperger's Disorder

    Science.gov (United States)

    Uono, Shota; Sato, Wataru; Toichi, Motomi

    2013-01-01

    This study was designed to identify specific difficulties and associated features related to the problems with social interaction experienced by individuals with pervasive developmental disorder-not otherwise specified (PDD-NOS) using an emotion-recognition task. We compared individuals with PDD-NOS or Asperger's disorder (ASP) and typically…

  6. Enhancing the Conversation Skills of a Boy with Asperger's Disorder through Social Stories[TM] and Video Modeling

    Science.gov (United States)

    Scattone, Dorothy

    2008-01-01

    This study combined Social Stories with video modeling in an effort to enhance the conversation skills of a boy with Asperger's Disorder. Treatment consisted of two components: (a) observation of video taped Social Stories that included two adults modeling targeted conversational skills and (b) 5-min social interactions. A multiple baseline design…

  7. Social Skills Deficits and Vocal Characteristics of Children with Social Phobia or Asperger's Disorder: A Comparative Study

    Science.gov (United States)

    Scharfstein, Lindsay A.; Beidel, Deborah C.; Sims, Valerie K.; Finnell, Laura Rendon

    2011-01-01

    Social skills deficits are commonly reported among children with social phobia (SP) and children with Asperger's Disorder (AD); however, a lack of direct comparison makes it unclear whether these groups, both of which endorse the presence of social anxiety, have similar or unique skills deficits. In this investigation, the social behaviors of…

  8. An Investigation of Upper Limb Motor Function in High Functioning Autism and Asperger's Disorder Using a Repetitive Fitts' Aiming Task

    Science.gov (United States)

    Papadopoulos, Nicole; McGinley, Jennifer; Tonge, Bruce J.; Bradshaw, John L.; Saunders, Kerryn; Rinehart, Nicole J.

    2012-01-01

    There is now a growing body of research examining movement difficulties in children diagnosed with high functioning autism (HFA) and Asperger's disorder (AD). Despite this, few studies have investigated the kinematic components of movement that may be disrupted in children diagnosed with these disorders. The current study investigated rapid aiming…

  9. Support for Learning Goes beyond Academic Support: Voices of Students with Asperger's Disorder and Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Bolic Baric, Vedrana; Hellberg, Kristina; Kjellberg, Anette; Hemmingsson, Helena

    2016-01-01

    The purpose of this study was to describe and explore the experiences of support at school among young adults with Asperger's disorder and attention deficit hyperactivity disorder and also to examine what support they, in retrospect, described as influencing learning. Purposive sampling was used to enroll participants. Data were collected through…

  10. Motor Proficiency and Emotional/Behavioural Disturbance in Autism and Asperger's Disorder: Another Piece of the Neurological Puzzle?

    Science.gov (United States)

    Papadopoulos, Nicole; McGinley, Jennifer; Tonge, Bruce; Bradshaw, John; Saunders, Kerryn; Murphy, Anna; Rinehart, Nicole

    2012-01-01

    The relationship of motor proficiency with emotional/behavioural disturbance, autistic symptoms and communication disturbance was investigated in children diagnosed with autism and Asperger's disorder (AD). The Movement Assessment Battery for Children was used as a measure of motor impairment, and the Developmental Behavioural Checklist was used…

  11. Brief Report: Making Experience Personal--Internal States Language in the Memory Narratives of Children with and without Asperger's Disorder

    Science.gov (United States)

    Brown, Benjamin T.; Morris, Gwynn; Nida, Robert E.; Baker-Ward, Lynne

    2012-01-01

    The development of the personal past is complex, requiring the operation of multiple components of cognitive and social functioning. Because many of these components are affected by autism spectrum disorders, it is likely that autobiographical memory in children with Asperger's Disorder (AD) will be impaired. We predicted that the memory…

  12. Brief report: the impact of changing from DSM-IV 'Asperger's' to DSM-5 'autistic spectrum disorder' diagnostic labels on stigma and treatment attitudes.

    Science.gov (United States)

    Ohan, Jeneva L; Ellefson, Sarah E; Corrigan, Patrick W

    2015-10-01

    In the DSM-5, 'Asperger's Disorder' was incorporated into 'Autistic Spectrum Disorder' (ASD). One key concern in this change has been that the ASD label will increase negative attitudes relative to the Asperger's label. To test this, we asked 465 American adults to read a vignette describing a child with autistic symptoms that included an ASD label, an Asperger's label, or no label, and rate their stigma and treatment attitudes (help-seeking and perceived effectiveness). Contrary to predictions, label did not impact stigma. Label did impact treatment attitudes, with greater help-seeking and perceived treatment effectiveness for both Asperger's and ASD labels. In sum, concern that the ASD label will increase negative perceptions, at least amongst the general public, is not supported. PMID:26043847

  13. Antiphospholipid Syndrome

    Science.gov (United States)

    ... Awards Enhancing Diversity Find People About NINDS NINDS Antiphospholipid Syndrome Information Page Synonym(s): Hughes Syndrome Table of Contents ( ... research is being done? Clinical Trials What is Antiphospholipid Syndrome? Antiphospholipid syndrome (APS) is an autoimmune disorder caused ...

  14. Pupils with Autism spectrum disorders in primary school

    OpenAIRE

    Kopun, Amanda

    2015-01-01

    The thesis includes the presentation of Asperger syndrome and strategies for teaching students with Asperger syndrome. It shows the survey on knowledge of Asperger syndrome among primary school teaches with experience and teachers with no experience in working with pupils with Asperger syndrome. It also includes the analysis of three interviews in which the characteristics of people with Asperger syndrome are presented. There are several autism spectrum disorders and the Asperger syndrome...

  15. Nouveau regard sur le comportement de l'asperge (Asparagus officinalis L.) multipliee in vitro

    OpenAIRE

    Dore, Claire

    1988-01-01

    La possibilité de multiplier végétativement in vitro l’asperge a permis notamment de cloner les parents des variétés hybrides de clones. L’obtention d’une griffe fonctionnelle dès le stade in vitro est un facteur essentiel de réussite de la micropropagation. Des améliorations permettant de maîtriser la méthode de clonage sont proposées ici. Une série de microbouturages est nécessaire pour induire ultérieurement de nombreux bourgeons qu’il est possible de fragmenter comme des griffes. Le...

  16. Metacognitive processes in emotion recognition: are they different in adults with Asperger's disorder?

    Science.gov (United States)

    Sawyer, Alyssa C P; Williamson, Paul; Young, Robyn

    2014-06-01

    Deficits in emotion recognition and social interaction characterize individuals with Asperger's Disorder (AS). Moreover they also appear to be less able to accurately use confidence to gauge their emotion recognition accuracy (i.e., metacognitive monitoring). The aim of this study was to extend this finding by considering both monitoring and control processes in emotion recognition among adults with AS. Those with AS were found to have difficulties acting on the basis of their metacognitive monitoring despite showing no deficits in their ability to discriminate accurate from inaccurate decisions. It is suggested that adults with AS have difficulties interacting socially because they are less able to assess when they are making accurate emotion recognition decisions despite having the capability to do so. PMID:24272525

  17. L’impacte familiar que suposa tenir un fill o una filla amb el trastorn d’Asperger

    OpenAIRE

    García Molina, Irene; Andrés Roqueta, Clara; Clemente Estevan, Rosa Ana

    2015-01-01

    L’objecte d’estudi que es presenta a continuació és l’impacte familiar, a través de les respostes de 10 famílies amb fills amb el trastorn d’Asperger; tots ells de l’Associació Asperger de Castelló. Es tracta d’un estudi que utilitza com a instrument un qüestionari adaptat de Donenberg i Baker. A més, aquest també conté respostes qualitatives en molts dels seus ítems. Els resultats semblen indicar que, el major impacte familiar vesa sobre l’àmbit econòmic, seguint-lo de ben...

  18. El autismo 70 años después de Leo Kanner y Hans Asperger

    OpenAIRE

    Artigas-Pallarès, Josep; Paula, Isabel

    2012-01-01

    A partir de las aportaciones de Leo Kanner (1943) y Hans Asperger (1944), el autismo ha sido foco de intenso debate, no sólo sobre aspectos fenomenológicos, etiológicos y terapéuticos;sino también sobre su propia naturaleza. La presente revisión pretende situar el autismo como un concepto dinámico sometido a interpretaciones no solo diversas, sino radicalmente enfrentadas.

  19. Differences and similarities in double special educational needs: high abilities/giftedness x Asperger’s Syndrome

    Directory of Open Access Journals (Sweden)

    Nara Joyce Wellausen Vieira

    2012-08-01

    Full Text Available The study was developed from a literature search in books, articles and theses that have been published since the year 2000 on the theme High Abilities / Giftedness and Asperger’s Syndrome. The objectives of this research were to conduct a search on publications from 2000 to 2011, about the common and different features to the person with Asperger syndrome and high ability gifted, and also relate the number of publications found in Education and Special Education. At theoretical we present the conception of High Abilities / Giftedness of Renzulli (2004 and Gardner (2000 and in the conception of Asperger Syndrome, Mello (2007 and Klin (2006. When analyzing the data, were perceived similarities and differences between the behavioral characteristics of individuals with High Abilities / Giftedness and those with Asperger’s Syndrome. It’s possible point out that there is much evidence that separate these two special educational needs and few similarities between them. But do not neglect that there may be a dual disability between these two particular special educational needs, because there are still few studies that verify theoretically the differences and similarities of these subjects, much less those that investigate these similarities and distinctions in the subjects themselves.

  20. The 5-HT(2A) receptor and serotonin transporter in Asperger's disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB.

    Science.gov (United States)

    Girgis, Ragy R; Slifstein, Mark; Xu, Xiaoyan; Frankle, W Gordon; Anagnostou, Evdokia; Wasserman, Stacey; Pepa, Lauren; Kolevzon, Alexander; Abi-Dargham, Anissa; Laruelle, Marc; Hollander, Eric

    2011-12-30

    Evidence from biochemical, imaging, and treatment studies suggest abnormalities of the serotonin system in autism spectrum disorders, in particular in frontolimbic areas of the brain. We used the radiotracers [(11)C]MDL 100907 and [(11)C]DASB to characterize the 5-HT(2A) receptor and serotonin transporter in Asperger's Disorder. Seventeen individuals with Asperger's Disorder (age=34.3 ± 11.1 years) and 17 healthy controls (age=33.0 ± 9.6 years) were scanned with [(11)C]MDL 100907. Of the 17 patients, eight (age=29.7 ± 7.0 years) were also scanned with [¹¹C]DASB, as were eight healthy controls (age=28.7 ± 7.0 years). Patients with Asperger's Disorder and healthy control subjects were matched for age, gender, and ethnicity, and all had normal intelligence. Metabolite-corrected arterial plasma inputs were collected and data analyzed by two-tissue compartment modeling. The primary outcome measure was regional binding potential BP(ND). Neither regional [¹¹C]MDL 100907 BP(ND) nor [¹¹C]DASB BP(ND) was statistically different between the Asperger's and healthy subjects. This study failed to find significant alterations in binding parameters of 5-HT(2A) receptors and serotonin transporters in adult subjects with Asperger's disorder. PMID:22079057

  1. Joubert Syndrome

    Science.gov (United States)

    ... Awards Enhancing Diversity Find People About NINDS NINDS Joubert Syndrome Information Page Table of Contents (click to ... Organizations Related NINDS Publications and Information What is Joubert Syndrome? Joubert syndrome is a rare brain malformation ...

  2. Marfan Syndrome

    Science.gov (United States)

    Marfan syndrome is a disorder that affects connective tissue. Connective tissues are proteins that support skin, bones, ... fibrillin. A problem with the fibrillin gene causes Marfan syndrome. Marfan syndrome can be mild to severe, ...

  3. Motivational processes and autonomic responsivity in Asperger's disorder: evidence from the Iowa Gambling Task.

    Science.gov (United States)

    Johnson, Shannon A; Yechiam, Eldad; Murphy, Robin R; Queller, Sarah; Stout, Julie C

    2006-09-01

    Asperger's disorder (ASP), like other autism spectrum disorders, is associated with altered responsiveness to social stimuli. This study investigated learning and responsiveness to nonsocial, but motivational, stimuli in ASP. We examined choice behavior and galvanic skin conductance responses (SCRs) during the Iowa Gambling Task (IGT; Bechara et al., 1994) in 15 adolescents and young adults with ASP and 14 comparison subjects. We examined aspects of learning, attention to wins and losses, and response style with a formal cognitive model, the Expectancy-Valence Learning model (Busemeyer & Stout, 2002). The ASP group did not differ from the comparison group in proportions of selections from advantageous decks. However, ASP participants showed a distinct pattern of selection characterized by frequent shifts between the four IGT decks, whereas comparison participants developed clear deck preferences. SCR results showed some evidence of reduced responsiveness in the ASP group during the IGT. Results from the cognitive model indicated that, in contrast to the comparison group, the ASP group's selections were less consistent with the motivational significance they assigned to decks. Findings are discussed in the context of the neurobiological substrates associated with IGT performance. PMID:16961948

  4. Ludoterapia de Criança com Síndrome de Asperger: Estudo de Caso

    Directory of Open Access Journals (Sweden)

    Fernanda Pereira Horta Rodrigues

    2013-04-01

    Full Text Available Este estudo objetivou discutir o processo psicoterapêutico de um menino de 12 anos de idade com Síndrome de Asperger, um transtorno global do desenvolvimento, atendido em um ambulatório de psicoterapia de um hospital público. O setting terapêutico e a caixa lúdica tiveram que ser modificados e flexibilizados para atender às peculiaridades da criança. São discutidos o vínculo terapêutico e a importância de se manejarem as diferenças entre eu/não-eu para a terapia. Percebeu-se que o atendimento, adaptado às condições do ambulatório público, contribuiu para a capacidade de comunicação e de interação da criança, fato que aponta para a importância do debate sobre a psicoterapia psicodinâmica com esta população e formas de realizá-la.

  5. A closer look at visually guided saccades in autism and Asperger's disorder.

    Science.gov (United States)

    Johnson, Beth P; Rinehart, Nicole J; Papadopoulos, Nicole; Tonge, Bruce; Millist, Lynette; White, Owen; Fielding, Joanne

    2012-01-01

    Motor impairments have been found to be a significant clinical feature associated with autism and Asperger's disorder (AD) in addition to core symptoms of communication and social cognition deficits. Motor deficits in high-functioning autism (HFA) and AD may differentiate these disorders, particularly with respect to the role of the cerebellum in motor functioning. Current neuroimaging and behavioral evidence suggests greater disruption of the cerebellum in HFA than AD. Investigations of ocular motor functioning have previously been used in clinical populations to assess the integrity of the cerebellar networks, through examination of saccade accuracy and the integrity of saccade dynamics. Previous investigations of visually guided saccades in HFA and AD have only assessed basic saccade metrics, such as latency, amplitude, and gain, as well as peak velocity. We used a simple visually guided saccade paradigm to further characterize the profile of visually guided saccade metrics and dynamics in HFA and AD. It was found that children with HFA, but not AD, were more inaccurate across both small (5°) and large (10°) target amplitudes, and final eye position was hypometric at 10°. These findings suggest greater functional disturbance of the cerebellum in HFA than AD, and suggest fundamental difficulties with visual error monitoring in HFA. PMID:23162442

  6. Kindler syndrome

    Directory of Open Access Journals (Sweden)

    Kaviarasan P

    2005-01-01

    Full Text Available Kindler syndrome is a rare autosomal recessive disorder associated with skin fragility. It is characterized by blistering in infancy, photosensitivity and progressive poikiloderma. The syndrome involves the skin and mucous membrane with radiological changes. The genetic defect has been identified on the short arm of chromosome 20. This report describes an 18-year-old patient with classical features like blistering and photosensitivity in childhood and the subsequent development of poikiloderma. The differential diagnosis of Kindler syndrome includes diseases like Bloom syndrome, Cockayne syndrome, dyskeratosis congenita, epidermolysis bullosa, Rothmund-Thomson syndrome and xeroderma pigmentosum. Our patient had classical cutaneous features of Kindler syndrome with phimosis as a complication.

  7. Inteligencia fluida y cristalizada en el autismo de alto funcionamiento y el síndrome de Asperger

    OpenAIRE

    Pérez, P.F.

    2016-01-01

    La inteligencia en los trastornos del espectro autista, especialmente en el autismo de alto funcionamiento y el síndrome de Asperger, ha sido tema de numerosas investigaciones que pretenden establecer la capacidad intelectual que se observa en estos sujetos. Algunos de los resultados más sobresalientes señalan que la inteligencia fluida es uno de los aspectos de desempeño superior en esta población, en comparación con el desempeño en las pruebas que miden inteligencia cristalizada como la esc...

  8. Programa de habilidades sociales para ni??os de cinco a??os con s??ndrome de Asperger

    OpenAIRE

    Serrano Gallardo, Teresa

    2014-01-01

    En el presente trabajo se expone un programa de intervenci??n basado en el entrenamiento de una serie de habilidades sociales con ni??os/as de cinco a??os con el S??ndrome de Asperger. Dado que estos ni??os/as tienen dificultades para mantener relaciones sociales con las personas que le rodean, se ha dise??ado un programa de intervenci??n en el que se proponen una serie de habilidades sociales b??sicas y complejas para su entrenamiento. Se persigue como objetivo general que se adquieran los r...

  9. The Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R): A Scale to Assist the Diagnosis of Autism Spectrum Disorder in Adults--An International Validation Study

    Science.gov (United States)

    Ritvo, Riva Ariella; Ritvo, Edward R.; Guthrie, Donald; Ritvo, Max J.; Hufnagel, Demetra H.; McMahon, William; Tonge, Bruce; Mataix-Cols, David; Jassi, Amita; Attwood, Tony; Eloff, Johann

    2011-01-01

    The Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R) is a valid and reliable instrument to assist the diagnosis of adults with Autism Spectrum Disorders (ASD). The 80-question scale was administered to 779 subjects (201 ASD and 578 comparisons). All ASD subjects met inclusion criteria: DSM-IV-TR, ADI/ADOS diagnoses and standardized IQ…

  10. The Swedish Version of the Ritvo Autism and Asperger Diagnostic Scale: Revised (RAADS-R). A Validation Study of a Rating Scale for Adults

    Science.gov (United States)

    Andersen, Lisa M. J.; Naswall, Katharina; Manouilenko, Irina; Nylander, Lena; Edgar, Johan; Ritvo, Riva Ariella; Ritvo, Edward; Bejerot, Susanne

    2011-01-01

    There is a paucity of diagnostic instruments for adults with autism spectrum disorder (ASD). This study evaluates the psychometric properties of the Swedish version of the Ritvo Autism and Asperger Diagnostic Scale-Revised (RAADS-R), an 80-item self-rating scale designed to assist clinicians diagnosing ASD in adults. It was administered to 75…

  11. Pseudo-Random Number Generation in Children with High-Functioning Autism and Asperger's Disorder: Further Evidence for a Dissociation in Executive Functioning?

    Science.gov (United States)

    Rinehart, Nicole J.; Bradshaw, John L.; Moss, Simon A.; Brereton, Avril V.; Tonge, Bruce J.

    2006-01-01

    The repetitive, stereotyped and obsessive behaviours, which are core diagnostic features of autism, are thought to be underpinned by executive dysfunction. This study examined executive impairment in individuals with autism and Asperger's disorder using a verbal equivalent of an established pseudo-random number generating task. Different patterns…

  12. Cognitive Profiles of Adults with Asperger's Disorder, High-Functioning Autism, and Pervasive Developmental Disorder Not Otherwise Specified Based on the WAIS-III

    Science.gov (United States)

    Kanai, Chieko; Tani, Masayuki; Hashimoto, Ryuichiro; Yamada, Takashi; Ota, Haruhisa; Watanabe, Hiromi; Iwanami, Akira; Kato, Nobumasa

    2012-01-01

    Little is known about the cognitive profiles of high-functioning Pervasive Developmental Disorders (PDD) in adults based on the Wechsler Intelligence Scale III (WAIS-III). We examined cognitive profiles of adults with no intellectual disability (IQ greater than 70), and in adults with Asperger's disorder (AS; n = 47), high-functioning autism (HFA;…

  13. Agreement in Multi-Informant Assessment of Behaviour and Emotional Problems and Social Functioning in Adolescents with Autistic and Asperger's Disorder

    Science.gov (United States)

    Jepsen, Matthew I.; Gray, Kylie M.; Taffe, John R.

    2012-01-01

    There is a paucity of evidence concerning the patterns of multi-informant agreement in populations with Autism Spectrum Disorders (ASD). This study compared ratings of behaviour and emotional problems and social functioning provided by 45 adolescents aged 12-18 years, with Autistic or Asperger's Disorder with ratings by their parents and teachers.…

  14. Syndrome d'Asperger: vignette clinique d'un enfant de 5 ans et évaluation diagnostique

    OpenAIRE

    Philippe, Paule; Scholl, Jean-Marc

    2008-01-01

    The child's parents consulted the Liege Autism Référence Center at Liège in 2007; the child was 5 years old. The main difficulties arise at school: the child does not follow the orders, disrupts the class; but except the school, he is very curious to learn, he possesses a surprising vocabulary and memory at his age The multidisciplinary team realized the clinical diagnostic work of assessment (neuropsychological tests, observations at school, at home, during consultations).The various ...

  15. Use of the Childhood Autism Rating Scale (CARS) for Children with High Functioning Autism or Asperger Syndrome

    Science.gov (United States)

    Mayes, Susan Dickerson; Calhoun, Susan L.; Murray, Michael J.; Morrow, Jill D.; Yurich, Kirsten K. L.; Cothren, Shiyoko; Purichia, Heather; Mahr, Fauzia; Bouder, James N.; Petersen, Christopher

    2012-01-01

    The authors of the "Childhood Autism Rating Scale" (CARS) state in the manual that the best cutoff score for distinguishing low functioning autism (LFA) from intellectual disability is 30 for children and 28 for adolescents and adults. This study determined that a cutoff score of 25.5 was most accurate in differentiating between high functioning…

  16. Research Reviews on Asperger Syndrome In China%国内Asperger综合征的研究现状

    Institute of Scientific and Technical Information of China (English)

    王辉

    2005-01-01

    Asperger综合征是一组以社交障碍和狭窄、刻板的兴趣行为为特征,但无语言发育障碍,且认知能力正常的儿童.为了了解国内对AS的研究现状,本文从AS的智力水平、对刺激信号的接受与加工过程、社会适应能力的研究、家庭环境因素对AS儿童的影响及干预方法等方面对国内当前的研究成果进行了梳理,以飨广大同仁.

  17. Analysis on intelligence of children with asperger syndrome%Asperger综合征儿童智力水平分析

    Institute of Scientific and Technical Information of China (English)

    陈凯云; 邹小兵; 唐春; 李建英; 邹园园

    2005-01-01

    目的探讨Asperger综合征儿童的智力水平和结构特点.方法采用韦氏儿童智力量表(C-WISC)对40名Asperger综合征患儿和59名正常儿童进行智力测试.结果 Asperger综合征儿童大部分(80%)智商在正常范围内,一小部分(17.5%)有智力缺损;其总智商、言语智商和操作智商分别为88.78±22.79,92.80±21.84,86.45±21.04,均低于正常儿童(P <0.05);且言语智商高于操作智商者较多(P <0.05).结论大部分Asperger综合征儿童智力正常,智力发展不平衡者较多.

  18. Can Gaze Avoidance Explain Why Individuals with Asperger's Syndrome Can't Recognise Emotions from Facial Expressions?

    Science.gov (United States)

    Sawyer, Alyssa C. P.; Williamson, Paul; Young, Robyn L.

    2012-01-01

    Research has shown that individuals with Autism Spectrum Disorders (ASD) have difficulties recognising emotions from facial expressions. Since eye contact is important for accurate emotion recognition, and individuals with ASD tend to avoid eye contact, this tendency for gaze aversion has been proposed as an explanation for the emotion recognition…

  19. Asperger综合征的家庭辅导%Psychological intervention for family of children with Asperger syndrome

    Institute of Scientific and Technical Information of China (English)

    陈一心; 詹明心

    2010-01-01

    [目的] 探讨Asperger综合征的家庭辅导,为有效治疗提供参考依据. [方法] 在对32例Asperger综合征患儿的发育、行为、交往模式、兴趣、特点等做出全面评估的基础上,采用家庭辅导的形式,主要给予患儿家庭心理支持和训练指导.以功能分析为前提,因势利导地个体化干预患儿的非适应性行为,训练社会意识和交往技能,培养语言实用性能力,并可结合感觉统合训练等. [结果] 32例患儿经过家庭辅导后情绪稳定、遵守纪律、社会交往和语言实用性改善、运动协调性增加、学业有进步. [结论] Asperger综合征需要建立一套个体化的家庭辅导方案,促使患儿不断进步.

  20. Support for learning goes beyond academic support: Voices of students with Asperger's disorder and attention deficit hyperactivity disorder.

    Science.gov (United States)

    Bolic Baric, Vedrana; Hellberg, Kristina; Kjellberg, Anette; Hemmingsson, Helena

    2016-02-01

    The purpose of this study was to describe and explore the experiences of support at school among young adults with Asperger's disorder and attention deficit hyperactivity disorder and also to examine what support they, in retrospect, described as influencing learning. Purposive sampling was used to enroll participants. Data were collected through semi-structured interviews with 13 young adults aged between 20 and 29 years. A qualitative analysis, based on interpreting people's experiences, was conducted by grouping and searching for patterns in data. The findings indicate that the participants experienced difficulties at school that included academic, social, and emotional conditions, all of which could influence learning. Support for learning included small groups, individualized teaching methods, teachers who cared, and practical and emotional support. These clusters together confirm the overall understanding that support for learning aligns academic and psychosocial support. In conclusion, academic support combined with psychosocial support at school seems to be crucial for learning among students with Asperger's disorder and attention deficit hyperactivity disorder. PMID:25911093

  1. Cushing's Syndrome

    Science.gov (United States)

    ... Cushing's syndrome, also called hypercortisolism , is a rare endocrine disorder caused by chronic exposure of the body's tissues ... removing the tumor while minimizing the chance of endocrine deficiency or long-term ... for Cushing's Syndrome Clinical Trials ...

  2. Turner Syndrome

    Science.gov (United States)

    Turner syndrome is a genetic disorder that affects a girl's development. The cause is a missing or incomplete ... t work properly. Other physical features typical of Turner syndrome are Short, "webbed" neck with folds of skin ...

  3. Metabolic Syndrome

    Science.gov (United States)

    Metabolic syndrome is a group of conditions that put you at risk for heart disease and diabetes. These ... doctors agree on the definition or cause of metabolic syndrome. The cause might be insulin resistance. Insulin is ...

  4. Pseudoaminopterin syndrome.

    Science.gov (United States)

    Kraoua, Lilia; Capri, Yline; Perrin, Laurence; Benmansour, Abdelmajjid; Verloes, Alain

    2012-09-01

    Pseudoaminopterin syndrome or aminopterin syndrome-like sine aminopterin (ASSA syndrome--OMIM 600325] is a rare autosomal recessive syndrome defined by characteristic dysmorphic features, skeletal defects, limb anomalies, cryptorchidism, and growth retardation. The syndrome owes its name to the fact that patients resemble the children exposed to aminopterin or to methotrexate, two dihydrofolate reductase inhibitors used for chemotherapy, or as an abortificient in early pregnancy. Ten patients have been described with pseudoaminopterin syndrome. Their phenotype is variable, and differs from the phenotype resulting from folic acid deprivation, leading to the notion that the pathogenesis may be more complex than simple vitamin deficiency. We report on an Algerian patient with pseudoaminopterin syndrome, review the previously reported cases and confirm that pseudoaminopterin syndrome does not result from a detectable contiguous gene imbalance as high resolution CGH array was normal in this child. PMID:22811276

  5. Usher Syndrome

    Science.gov (United States)

    Usher syndrome is an inherited disease that causes serious hearing loss and retinitis pigmentosa, an eye disorder ... hearing and vision. There are three types of Usher syndrome: People with type I are deaf from ...

  6. Turner Syndrome

    Science.gov (United States)

    Turner syndrome is a genetic disorder that affects a girl's development. The cause is a missing or ... t work properly. Other physical features typical of Turner syndrome are Short, "webbed" neck with folds of ...

  7. Proteus Syndrome

    Science.gov (United States)

    ... Gift Stock Gift Sunshine Society Contact Privacy Policy Proteus Syndrome Definition Common Signs Diagnostic Criteria (I have ... NIH to go with this criteria) Glossary Videos Proteus Syndrome is a condition which involves atypical growth ...

  8. Learning about Marfan Syndrome

    Science.gov (United States)

    ... genetic terms used on this page Learning About Marfan Syndrome What is Marfan syndrome? What are the ... Syndrome Additional Resources for Marfan Syndrome What is Marfan syndrome? Marfan syndrome is one of the most ...

  9. Alagille syndrome.

    OpenAIRE

    Krantz, I D; Piccoli, D A; Spinner, N B

    1997-01-01

    Alagille syndrome (OMIM 118450) is an autosomal dominant disorder associated with abnormalities of the liver, heart, eye, skeleton, and a characteristic facial appearance. Also referred to as the Alagille-Watson syndrome, syndromic bile duct paucity, and arteriohepatic dysplasia, it is a significant cause of neonatal jaundice and cholestasis in older children. In the fully expressed syndrome, affected subjects have intrahepatic bile duct paucity and cholestasis, in conjunction with cardiac ma...

  10. Cushing Syndrome

    Science.gov (United States)

    ... links Share this: Page Content What is Cushing’s syndrome? Cushing’s syndrome is a condition that occurs when the body’s ... medication or as a result of a tumor, Cushing’s syndrome can develop. Many factors influence whether this happens, ...

  11. Dumping Syndrome

    Science.gov (United States)

    ... Disease Organizations​​ (PDF, 341 KB)​​​​​ Alternate Language URL Dumping Syndrome Page Content On this page: What is ... Nutrition Points to Remember Clinical Trials What is dumping syndrome? Dumping syndrome occurs when food, especially sugar, ...

  12. A theoretical approach of Asperger’s syndrome in children

    Directory of Open Access Journals (Sweden)

    Chrysoula Valamoutopoulou

    2010-07-01

    Full Text Available The Asperger’s Syndrome is reported in the pervasive developmental disorders and was categorized as a separate disorder, initially in the ICD‐10 (World Health Organization, 1992 and afterwards in the DSM‐IV (American Psychiatric Organization, 1994. The Asperger’s Syndrome is distinguished by a team of symptoms that concern the low output in the social interaction and the communication dexterities, as well as the increased stereotypical behavior in various activities and interests.Aim: The aim of this present study was the descriptive review of bibliography concerning the epidemiology, the differential diagnosis from the autism, the etiology, the diagnosis, the therapeutic approaches and the adaptation difficulty of the family environment, with regard to the investigation of the Asperger ’s syndrome.Material and method: In the present review, the methodology that was followed included specialized electronic research with regard to the Asperger’s syndrome in children, using special keywords.Results: The review of the bibliography showed that the individuals with Asperger’s syndrome experience really big difficulties in elementary social behaviors, as failure in the growth and creation of friendly relations or in the search of amusing activities with others. Also, they face difficulties in the comprehension of not verbal communication (body language and the other’s expressions, the attitudes of body and the eye contact.Conclusions: The precocious recognition of Asperger’ s syndrome is imperative, with final objective the continuous briefing and sensitization of all health professionals as well as the wider public toward this, under the prism of interdisciplinary approach.

  13. Mozart's movements and behaviour: a case of Tourette's syndrome?

    Science.gov (United States)

    Ashoori, A; Jankovic, J

    2008-06-01

    In this review, we intend to explore the often asked question: "Did Mozart have Tourette's syndrome?" Although there are numerous reports attributing Mozart's peculiar personality and behaviour to a spectrum of neurobehavioural disorders such as Tourette's syndrome, autistic disorder, Asperger's syndrome, attention deficit hyperactivity disorder, obsessive-compulsive disorder and paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection, the evidence for any of these disorders is lacking. Whether Mozart's behaviour was nothing more than a reflection of his unique personality or a more complex neurological disorder, aggravated later in life by enormous demands by his father and society, his behaviour has been the subject of many biographies. It will also remain unknown to what extent his accomplishments and failures were shaped by his childhood experiences, pressured lifestyle, and his innate genius and extraordinary talent. Lessons from his life may have important implications for other gifted individuals and savants whose special attributes may lead them to succeed or, on the other hand, suppress their emotional growth and make them more vulnerable to stress and failure. PMID:18644922

  14. [Developmental course of patients with Asperger's disorder followed objectively from infancy].

    Science.gov (United States)

    Yoshioka, Mieko; Isaka, Masako

    2012-01-01

    This follow-up study evaluated cognitive and language development in Asperger's disorder (AD) patients diagnosed at the age of 5 to 6 years, with initial complaints of delays in motor or language development in infancy. We evaluated 12 patients (10 males and 2 females) using two intelligence tests:Kyoto Scale of Psychological Development 2001 (K-scale) for those under 6 years, and WISC-III for those over 5-6 years. The cognitive-adaptive area (C-A) of the former test was compared to the performance IQ (PIQ) of the latter test, and the language-social area (L-S) of the former to verbal IQ (VIQ) of the latter. The mean age at the first examination was 3.2 years (range:2.1-4.6 years), and the average age at follow-up was 7.7 years (range:5.3-12.3 years). The average length of follow-up from the initial visit was 5.6 years (range:3.3-8.6 years). During follow-up, the PIQ, VIQ and full scale DQ or IQ (F-DQ/IQ) improved with age. Average scores of the 12 patients at the first examination and last follow-up evaluated by K-scale were:C-A:70.6 (first) and 84.5 (last), L-S:64.8 (first) and 85.8 (last), and F-DQ:68.5 (first) and 84.8 (last). Compared to those with AD, 12 autistic patients with the Kanner type (10 males and 2 females) who visited our clinic during almost the same period, and belonged to almost the same age group, showed average scores at the first examination and last follow-up of:C-A: 61.9 (first) and43.3 (last), L-S:43.0 (first) and43.4 (last), and F-DQ:60.2 (first) and44.5 (last). From these observations, it is apparent that AD patients also showed language delay during infancy, but they improved rapidly between the ages of 4-6 years. This developmental spurt was not seen in autistic patients with the Kanner type. PMID:22352033

  15. Aydın ili lise öğrencilerinde Asperger bozukluğunun yaygınlığı ve Asperger bozukluğunda zihin kuramı

    OpenAIRE

    Akoğuz, Gökçehan

    2014-01-01

    Nörogelişimsel bir bozukluk olan Asperger Bozukluğu, ergen ve erişkinlerde pek çok farklı tanıyla takip edilebildiğinden sıklıkla göz ardı edilmektedir ve yaygınlığıyla ilgili bilgiler sınırlıdır. Bu bozuklukta, sosyal etkileşim alanlarında, sözel ve sözel olmayan iletişim alanlarında sorunlar olabilir. Empati de bu alanlardan biridir. Yapılan çalışmalarda, Otizm benzeri özellikler gösteren bireylerde empati becerilerindeki bozulmaların daha fazla olduğu bulunmuştur. Empati sis...

  16. Coping, daily hassles and behavior and emotional problems in adolescents with high-functioning autism/Asperger's Disorder.

    Science.gov (United States)

    Khor, Angela S; Melvin, Glenn A; Reid, Sophie C; Gray, Kylie M

    2014-03-01

    Although daily hassles and coping are associated with behavior and emotional problems in non-clinical populations, few studies have investigated these relationships in individuals with high-functioning autism/Asperger's Disorder (HFASD). This study examined the relationships between daily hassles, coping and behavior and emotional problems in adolescents with HFASD. Thirty-one adolescents with HFASD completed questionnaires assessing their coping and behavior and emotional problems, and completed an Ecological Momentary Assessment run via a mobile phone application on their coping and daily hassles. Parents completed questionnaires of the adolescents' daily hassles, coping, and behavior and emotional problems. The disengagement coping style was associated with significantly higher levels of behavior and emotional problems regardless of respondent or methodology, suggesting it may be a valuable target for intervention. PMID:23933998

  17. Brief report: making experience personal: internal states language in the memory narratives of children with and without Asperger's disorder.

    Science.gov (United States)

    Brown, Benjamin T; Morris, Gwynn; Nida, Robert E; Baker-Ward, Lynne

    2012-03-01

    The development of the personal past is complex, requiring the operation of multiple components of cognitive and social functioning. Because many of these components are affected by autism spectrum disorders, it is likely that autobiographical memory in children with Asperger's Disorder (AD) will be impaired. We predicted that the memory narratives of children with AD, in comparison to typically-developing peers, would reflect less personal interpretation as evidenced by internal states language. Thirty children with AD and 20 typically-developing children aged 6-14 reported their earliest memories and two emotional experiences (one positive and one negative). Consistent with our predictions, children with AD included fewer emotional, cognitive, and perceptual terms than the comparison sample. PMID:21503798

  18. A meta-analysis of differences in IQ profiles between individuals with Asperger's disorder and high-functioning autism.

    Science.gov (United States)

    Chiang, Hsu-Min; Tsai, Luke Y; Cheung, Ying Kuen; Brown, Alice; Li, Huacheng

    2014-07-01

    A meta-analysis was performed to examine differences in IQ profiles between individuals with Asperger's disorder (AspD) and high-functioning autism (HFA). Fifty-two studies were included for this study. The results showed that (a) individuals with AspD had significantly higher full-scale IQ, verbal IQ (VIQ), and performance IQ (PIQ) than did individuals with HFA; (b) individuals with AspD had significantly higher VIQ than PIQ; and (c) VIQ was similar to PIQ in individuals with HFA. These findings seem to suggest that AspD and HFA are two different subtypes of Autism. The implications of the present findings to DSM-5 Autism Spectrum Disorder are discussed. PMID:24362849

  19. Urofacial syndrome

    Directory of Open Access Journals (Sweden)

    Kamal F Akl

    2012-01-01

    Full Text Available The urofacial syndrome is characterized by functional obstructive uropathy asso-ciated with an inverted smile. The importance of the subject is that it sheds light, not only on the muscles of facial expression, but also on the inheritance of voiding disorders and lower urinary tract malformations. We report a 10-year-old-male patient who had the urofacial syndrome. Early diagnosis of the urofacial syndrome is important to avoid upper urinary tract damage and renal failure.

  20. Waardenburg syndrome.

    OpenAIRE

    Read, A P; Newton, V E

    1997-01-01

    Auditory-pigmentary syndromes are caused by physical absence of melanocytes from the skin, hair, eyes, or the stria vascularis of the cochlea. Dominantly inherited examples with patchy depigmentation are usually labelled Waardenburg syndrome (WS). Type I WS, characterised by dystopia canthorum, is caused by loss of function mutations in the PAX3 gene. Type III WS (Klein-Waardenburg syndrome, with abnormalities of the arms) is an extreme presentation of type I; some but not all patients are ho...

  1. Sweet Syndrome

    OpenAIRE

    Kasapçopur, Özgür; Sever, Lale; Çalışkan, Salim; Kodakoğlu, Ramazan; Mat, Cem; Kaner, Gültekin; Arısoy, Nil

    1996-01-01

    Sweet syndrome is a vasculitis characterized with fever leucocytosis neutrophilia and dermal neutrophilic infiltration In children Sweet syndrome usually occurs with secondary to infection and in adults to malignancy We report a Sweet syndrome in a five years old girl with respiratory infections otitis dactylitis long lasting fever and cutaneous rash A neutrophilic dermal infiltration is noted in cutaneous biopsy These signs have disappeared with corticosteroid treatment In conclusion Sweet s...

  2. Revesz syndrome

    Directory of Open Access Journals (Sweden)

    Dayane Cristine Issaho

    2015-04-01

    Full Text Available Revesz syndrome is a rare variant of dyskeratosis congenita and is characterized by bilateral exudative retinopathy, alterations in the anterior ocular segment, intrauterine growth retardation, fine sparse hair, reticulate skin pigmentation, bone marrow failure, cerebral calcification, cerebellar hypoplasia and psychomotor retardation. Few patients with this syndrome have been reported, and significant clinical variations exist among patients. This report describes the first Brazilian case of Revesz syndrome and its ocular and clinical features.

  3. Metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Gogia Atul

    2006-02-01

    Full Text Available The Metabolic syndrome is a widely prevalent and multi-factorial disorder. The syndrome has been given several names, including- the metabolic syndrome, the insulin resistance syndrome, the plurimetabolic syndrome, and the deadly quartet. With the formulation of NCEP/ATP III guidelines, some uniformity and standardization has occurred in the definition of metabolic syndrome and has been very useful for epidemiological purposes. The mechanisms underlying the metabolic syndrome are not fully known; however resistance to insulin stimulated glucose uptake seems to modify biochemical responses in a way that predisposes to metabolic risk factors. The clinical relevance of the metabolic syndrome is related to its role in the development of cardiovascular disease. Management of the metabolic syndrome involves patient-education and intervention at various levels. Weight reduction is one of the main stays of treatment. In this article we comprehensively discuss this syndrome- the epidemiology, pathogenesis, clinical relevance and management. The need to do a comprehensive review of this particular syndrome has arisen in view of the ever increasing incidence of this entitiy. Soon, metabolic syndrome will overtake cigarette smoking as the number one risk factor for heart disease among the US population. Hardly any issue of any primary care medical journal can be opened without encountering an article on type 2 diabetes, dyslipidemia or hypertension. It is rare to see type 2 diabetes, dyslipidemia, obesity or hypertension in isolation. Insulin resistance and resulting hyperinsulinemia have been implicated in the development of glucose intolerance (and progression to type 2 diabetes, hypertriglyceridemia, hypertension, polycystic ovary yndrome, hypercoagulability and vascular inflammation, as well as the eventual development of atherosclerotic cardiovascular disease manifested as myocardial infarction, stroke and myriad end organ diseases. Conversely

  4. Brugada syndrome

    Directory of Open Access Journals (Sweden)

    Bockeria O.L.

    2015-03-01

    Full Text Available Brugada syndrome is characterized by sudden death associated with one of several ECG patterns including incomplete right bundle-branch block and ST-segment elevation in the anterior precordial leads. According to the ECG patterns there are three types of Brugada syndrome. Brugada syndrome is genetically determined and has an autosomal dominant pattern of transmission in about 50% of familial cases. Nowadays implantation of cardioverter-defibrillator is the only proven method of sudden cardiac death prevention.

  5. Velocardiofacial syndrome.

    OpenAIRE

    Pike, A. C.; Super, M.

    1997-01-01

    Velocardiofacial syndrome is a syndrome of multiple anomalies that include cleft palate, cardiac defects, learning difficulties, speech disorder and characteristic facial features. It has an estimated incidence of 1 in 5000. The majority of cases have a microdeletion of chromosome 22q11.2. The phenotype of this condition shows considerable variation, not all the principal features are present in each case. Identification of the syndrome can be difficult as many of the anomalies are minor and ...

  6. Sheehan syndrome

    Science.gov (United States)

    Postpartum hypopituitarism; Postpartum pituitary insufficiency; Hypopituitarism Syndrome ... Malee MP. Pituitary and adrenal disorders in pregnancy. In: Gabbe ... Problem Pregnancies . 6th ed. Philadelphia, PA: Elsevier Mosby; ...

  7. What Is Down Syndrome?

    Science.gov (United States)

    ... NDSS Home » Down Syndrome » What Is Down Syndrome? What Is Down Syndrome? In every cell in the ... chromosome 21 causes the characteristics of Down syndrome. What Causes Down Syndrome? Regardless of the type of ...

  8. Marfan Syndrome (For Teens)

    Science.gov (United States)

    ... How Can I Help a Friend Who Cuts? Marfan Syndrome KidsHealth > For Teens > Marfan Syndrome Print A ... a genetic disorder called Marfan syndrome. What Is Marfan Syndrome? Marfan syndrome is named after Antoine Marfan, ...

  9. Down Syndrome: Eye Problems

    Science.gov (United States)

    ... En Español Read in Chinese What causes Down syndrome? Down syndrome is caused by a duplication of all ... in persons with Down syndrome. How common is Down syndrome? The frequency of Down syndrome is approximately 1 ...

  10. Proteus Syndrome Foundation

    Science.gov (United States)

    ... Gift Stock Gift Sunshine Society Contact Privacy Policy Proteus Syndrome Foundation The Proteus Syndrome Foundation , a 501c3 ... 1 Trial with ARQ 092 in Proteus Syndrome Proteus Syndrome Patient Registry The Proteus Syndrome Foundation Contact ...

  11. The Swedish Version of the Ritvo Autism and Asperger Diagnostic Scale: Revised (RAADS-R). A Validation Study of a Rating Scale for Adults

    OpenAIRE

    Andersen, Lisa M. J.; Naswall, Katharina; Manouilenko, Irina; Nylander, Lena; Edgar, Johan; Ariella Ritvo, Riva; Ritvo, Edward; Bejerot, Susanne

    2011-01-01

    There is a paucity of diagnostic instruments for adults with autism spectrum disorder (ASD). This study evaluates the psychometric properties of the Swedish version of the Ritvo Autism and Asperger Diagnostic Scale-Revised (RAADS-R), an 80-item self-rating scale designed to assist clinicians diagnosing ASD in adults. It was administered to 75 adults with ASD and 197 comparison cases. Also, a subset completed the Autism Spectrum Quotient (AQ). Three out of four subscales had high internal cons...

  12. The Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R): A Scale to Assist the Diagnosis of Autism Spectrum Disorder in Adults: An International Validation Study

    OpenAIRE

    Ritvo, Riva Ariella; Ritvo, Edward R.; Guthrie, Donald; Ritvo, Max J.; Hufnagel, Demetra H.; Mcmahon, William,; Tonge, Bruce; Mataix-Cols, David; Jassi, Amita; Attwood, Tony; Eloff, Johann

    2010-01-01

    The Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R) is a valid and reliable instrument to assist the diagnosis of adults with Autism Spectrum Disorders (ASD). The 80-question scale was administered to 779 subjects (201 ASD and 578 comparisons). All ASD subjects met inclusion criteria: DSM-IV-TR, ADI/ADOS diagnoses and standardized IQ testing. Mean scores for each of the questions and total mean ASD vs. the comparison groups’ scores were significantly different (p 

  13. An Examination of Movement Kinematics in Young People with High-functioning Autism and Asperger's Disorder: Further Evidence for a Motor Planning Deficit

    OpenAIRE

    Rinehart, Nicole J.; Bellgrove, Mark A.; Tonge, Bruce J.; Brereton, Avril V.; Howells-Rankin, Debra; Bradshaw, John L.

    2006-01-01

    This paper examines upper-body movement kinematics in individuals with high-functioning autism (HFA) and Asperger's disorder (AD). In general, the results indicate that HFA is more consistently associated with impaired motoric preparation/initiation than AD. The data further suggest that this quantitative difference in motor impairment is not necessarily underpinned by greater executive dysfunction vulnerability in autism relative to AD. Quantitative motoric dissociation between autism and AD...

  14. Turner Syndrome

    Directory of Open Access Journals (Sweden)

    Ravinder K. Gupta, Ritu Gupta, Sunil Dutt Sharma

    2006-10-01

    Full Text Available Turner Syndrome is one of the important chromosomal disorders characterised by loss (total or part ofsex chromosome. The manifestations being peripheral edema, short stature, extra skin fold, webbing ofneck, renal and cardiovascular anomalies, sexual infantilism, learning disability etc. We present here aone month female baby who had classical features of Turner Syndrome. The karyotape analysis wasconsistent with the diagnosis.

  15. Turner Syndrome

    Directory of Open Access Journals (Sweden)

    Akcan AB.

    2013-06-01

    Full Text Available Turner syndrome is an important cause of short stature in girls and primer amenorrhea in young women that is usually caused by loss of part or all of an X chromosome. This topic will review the clinical manifestations, diagnosis and management of Turner syndrome.

  16. Tourette Syndrome.

    Science.gov (United States)

    Look, Kathy

    Tourette Syndrome has a history of being misdiagnosed or undiagnosed due to its unusual and complex symptoms. This paper describes: the symptoms of Tourette Syndrome; its etiology; age of onset; therapeutic methods, such as drug therapy, psychotherapy, diet control, and hypnosis; educational implications; and employment prospects. Several…

  17. Antiphospholipid syndrome

    DEFF Research Database (Denmark)

    Cervera, Ricard; Piette, Jean-Charles; Font, Josep;

    2002-01-01

    To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression.......To analyze the clinical and immunologic manifestations of antiphospholipid syndrome (APS) in a large cohort of patients and to define patterns of disease expression....

  18. Proteus syndrome

    Directory of Open Access Journals (Sweden)

    George Renu

    1993-01-01

    Full Text Available A case of proteus syndrome in a 20 year old male is repoted. Hemihypertrophy, asymmetric megalodactyly, linear epidermal naevus, naevus flammeus, angiokeratoma, lymphangioma circumscriptum, thickening of the palms and soles, scoliosis and varicose veins were present. There are only few reports of these cases in adults. The syndrome has not been reported from India.

  19. Burnout Syndrome

    OpenAIRE

    Panova, Gordana; Panov, Nenad; Stojanov, H; Sumanov, Gorgi; Panova, Blagica; Stojanovski, Angel; Nikolovska, Lence; Jovevska, Svetlana; Trajanovski, D; Asanova, D

    2013-01-01

    Introduction: Increasing work responsibilities, allocation of duties, loss of energy and motivation in everyday activities, emotional exhaustion, lack of time for themselves, insuffi cient time for rest and recreation, dissatisfaction in private life. All these symptoms can be cause of Burnout Syndrome. Aim: To see the importance of this syndrome, the consequences of job dissatisfaction, the environment, family and expression in drastic chan...

  20. Poland syndrome

    Directory of Open Access Journals (Sweden)

    Chandra Madhur Sharma

    2014-01-01

    Full Text Available Poland′s syndrome is a rare congenital condition, characterized by the absence of the sternal or breastbone portion of the pectoralis major muscle, which may be associated with the absence of nearby musculoskeletal structures. We hereby report an 8-year-old boy with typical features of Poland syndrome, the first documented case from Uttar Pradesh, India.

  1. Noonan Syndrome

    Directory of Open Access Journals (Sweden)

    Sanjeev K. Digra, Deep Aman Singh, Vikram Gupta, Ghanshyam Saini

    2004-10-01

    Full Text Available We report a 11 year old boy and his father both Noonan’s. Noonan syndrome occurs in 1 out of 2000live births. Short stature, webbing of neck, pectus carinatum or pectus excavatum, hypertelorismcubitus valgus, epicanthus, downward slanted palpebral fissures, ptosis, microganthia and earabnormalities are the common features of Noonan syndrome.

  2. Bloom's Syndrome

    Science.gov (United States)

    ... Niemann-Pick Disease, Type A Spinal Muscular Atrophy Tay-Sachs Disease Usher Syndrome, Type 1F and Type III ... Niemann-Pick Disease, Type A Spinal Muscular Atrophy Tay-Sachs Disease Usher Syndrome, Type 1F and Type III ...

  3. Kounis syndrome.

    Science.gov (United States)

    Ntuli, P M; Makambwa, E

    2015-10-01

    Kounis syndrome is characterised by a group of symptoms that manifest as unstable vasospastic or non-vasospastic angina secondary to a hypersensitivity reaction. It was first described by Kounis and Zavras in 1991 as the concurrence of an allergic response with an anaphylactoid or anaphylactic reaction and coronary artery spasm or even myocardial infarction. Since then, this condition has evolved to include a number of mast cell activation disorders associated with acute coronary syndrome. There are many triggering factors, including reactions to multiple medications, exposure to radiological contrast media, poison ivy, bee stings, shellfish and coronary stents. In addition to coronary arterial involvement, Kounis syndrome comprises other arterial systems with similar physiologies, such as mesenteric and cerebral circulation resulting in ischaemia/infarction of the vital organs. The incidence of this condition is difficult to establish owing to the number of potential instigating factors and its relatively infrequent documentation in the literature.We report the case of an HIV-negative 39-year-old man with no coronary risk factors or family history of premature coronary artery disease, who developed Kounis syndrome after the administration of fluoroquinolone for dysuria. However, to the best of our knowledge,no data on the incidence and prevalence of Kounis syndrome in South Africa have ever been reported in the literature. The recent understanding of Kounis syndrome has led to the condition being classified into three syndrome variants. PMID:26636160

  4. HYDROLETHALUS SYNDROME

    Directory of Open Access Journals (Sweden)

    Aradhana

    2013-06-01

    Full Text Available INTRODUCTION: Hydrolethalus Syndrome (HLS is a rare lethal genetic syndrome, recognized as a consequence of a study on Meckle syndrome in Finland .1 HLS is characterized by multiple developmental defects of fetus which include fetal hydrocephalus, agenesis of corpus callosum, absent midline structures of brain, Cleft lip and cleft palate, defective lobulation of lungs, micrognathia and very characteristic abnormality of polydactyly. About 80% of patients have polydactyly, in hands it is postaxial and preaxial in feet with duplicated big toe. A highly characteristic hallux duplex is seen in almost no other situation .2 Club feet is also common.

  5. Neuroacanthocytosis Syndromes

    Directory of Open Access Journals (Sweden)

    Walker Ruth H

    2011-10-01

    Full Text Available Abstract Neuroacanthocytosis (NA syndromes are a group of genetically defined diseases characterized by the association of red blood cell acanthocytosis and progressive degeneration of the basal ganglia. NA syndromes are exceptionally rare with an estimated prevalence of less than 1 to 5 per 1'000'000 inhabitants for each disorder. The core NA syndromes include autosomal recessive chorea-acanthocytosis and X-linked McLeod syndrome which have a Huntington´s disease-like phenotype consisting of a choreatic movement disorder, psychiatric manifestations and cognitive decline, and additional multi-system features including myopathy and axonal neuropathy. In addition, cardiomyopathy may occur in McLeod syndrome. Acanthocytes are also found in a proportion of patients with autosomal dominant Huntington's disease-like 2, autosomal recessive pantothenate kinase-associated neurodegeneration and several inherited disorders of lipoprotein metabolism, namely abetalipoproteinemia (Bassen-Kornzweig syndrome and hypobetalipoproteinemia leading to vitamin E malabsorption. The latter disorders are characterized by a peripheral neuropathy and sensory ataxia due to dorsal column degeneration, but movement disorders and cognitive impairment are not present. NA syndromes are caused by disease-specific genetic mutations. The mechanism by which these mutations cause neurodegeneration is not known. The association of the acanthocytic membrane abnormality with selective degeneration of the basal ganglia, however, suggests a common pathogenetic pathway. Laboratory tests include blood smears to detect acanthocytosis and determination of serum creatine kinase. Cerebral magnetic resonance imaging may demonstrate striatal atrophy. Kell and Kx blood group antigens are reduced or absent in McLeod syndrome. Western blot for chorein demonstrates absence of this protein in red blood cells of chorea-acanthocytosis patients. Specific genetic testing is possible in all NA syndromes

  6. Piriformis syndrome

    Science.gov (United States)

    ... Wallet sciatica; Hip socket neuropathy; Pelvic outlet syndrome; Low back pain - piriformis ... medical help immediately if: You have sudden severe pain in your lower back or legs, along with muscle weakness or numbness ...

  7. Rett syndrome

    Science.gov (United States)

    An infant with Rett syndrome usually has normal development for the first 6 to 18 months. Symptoms range from ... of social engagement Ongoing, severe constipation and gastroesophageal reflux (GERD ) Poor circulation that can lead to cold ...

  8. Gardner Syndrome

    Science.gov (United States)

    ... syndromes. For more information, talk with an assisted reproduction specialist at a fertility clinic. How common is ... detected X-ray or computed tomography (CT or CAT) scan of the small bowel if adenomas are ...

  9. Piriformis Syndrome

    Science.gov (United States)

    ... syndrome occurs when this muscle presses on your sciatic nerve (the nerve that goes from your spinal cord ... cause the piriformis muscle to press against the sciatic nerve, such as sitting, walking up stairs or running. ...

  10. Marfan Syndrome

    Science.gov (United States)

    ... caved-in look. He also wore glasses for myopia (say: my-OH-pee-uh), or nearsightedness, which ... syndrome, this "glue" is weaker than normal. This causes changes in many systems of the body, but ...

  11. Aase syndrome

    Science.gov (United States)

    ... a provider who has experience treating anemias. A bone marrow transplant may be necessary if other treatment fails. ... counseling is recommended if you have a family history of this syndrome and wish to become pregnant.

  12. Hunter syndrome

    Science.gov (United States)

    ... to your health care provider for more information. Bone marrow transplant has been tried for the early-onset form, ... to have children and who have a family history of Hunter syndrome. Prenatal testing is available. Carrier ...

  13. Hurler syndrome

    Science.gov (United States)

    ... to your health care provider for more information. Bone marrow transplant has been used in several people with this ... Call your provider if: You have a family history of Hurler syndrome and are considering having children ...

  14. [Heptopulmonary syndrome].

    Science.gov (United States)

    Cuadrado, Antonio; Díaz, Ainhoa; Iruzubieta, Paula; Salcines, José Ramón; Crespo, Javier

    2015-01-01

    Hepatopulmonary syndrome is characterized by the presence of liver disease, pulmonary vascular dilatations, and arterial hypoxemia. It is usually associated with cirrhosis of any origin, but has been described in other liver diseases, both acute and chronic, and not always associated with portal hypertension. The gold standard method to detect pulmonary vascular dilations is contrast enhancement echocardiography with saline and is essential for the diagnosis of hepatopulmonary syndrome. These dilatations reflect changes in the pulmonary microvasculature (vasodilatation, intravascular monocyte accumulation, and angiogenesis) and induce a ventilation/perfusion mismatch, or even true intrapulmonary shunts, which eventually trigger hypoxemia. This syndrome worsens patients' prognosis and impairs their quality of life and may lead to the need for liver transplantation, which is the only effective and definitive treatment. In this article, we review the etiological, pathophysiological, clinical and therapeutic features of this syndrome. PMID:25840463

  15. Turcot Syndrome

    Science.gov (United States)

    ... procedure done in conjunction with in-vitro fertilization (IVF). It allows people who carry a specific known ... screening? If you are concerned about your family history and think your family may have Turcot syndrome, ...

  16. Levator Syndrome

    Science.gov (United States)

    ... 2 Diabetes, Heart Disease a Dangerous Combo Are 'Workaholics' Prone to OCD, Anxiety? ALL NEWS > Resources First ... are variations of levator syndrome. The muscle spasm causes pain that typically is not related to defecation. ...

  17. Pendred Syndrome

    Science.gov (United States)

    ... Health & Human Services National Institutes of Health Search Search form Search A–Z Index Español Menu Home ... children, the thyroid is important for normal growth and development. Children with Pendred syndrome, however, rarely have problems ...

  18. Goodpasture syndrome

    Science.gov (United States)

    ... glomerulonephritis with pulmonary hemorrhage; Pulmonary renal syndrome; Glomerulonephritis - pulmonary hemorrhage ... when urinating Nausea and vomiting Pale skin Swelling (edema) in any area of the body, especially in the legs

  19. Tourette Syndrome

    Science.gov (United States)

    ... methylphenidate and clonidine in children with ADHD and tics. Developing New Treatments for Tourette Syndrome: Clinical and Basic Science Dialogue Publicaciones en Español Síndrome de Tourette Prepared ...

  20. Alport Syndrome

    Science.gov (United States)

    ... syndrome diagnosed? Your healthcare provider will have to watch your signs, symptoms, and look at your family ... 05/2016 - 10:00am Philadelphia, PA Kidney Camp Sun, 07/17/2016 - 6:00pm Ingleside, IL Register ...