4th International Conference on Dynamics in Logistics

CERN Document Server

Pannek, Jürgen; Thoben, Klaus-Dieter

2016-01-01

This contributed volume brings together research papers presented at the 4th International Conference on Dynamics in Logistics, held in Bremen, Germany in February 2014. The conference focused on the identification, analysis and description of the dynamics of logistics processes and networks. Topics covered range from the modeling and planning of processes, to innovative methods like autonomous control and knowledge management, to the latest technologies provided by radio frequency identification, mobile communication, and networking. The growing dynamic poses wholly new challenges: logistics processes and networks must be(come) able to rapidly and flexibly adapt to constantly changing conditions. The book primarily addresses the needs of researchers and practitioners from the field of logistics, but will also be beneficial for graduate students.

4th International Workshop on Adaptive Optics for Industry and Medicine

CERN Document Server

Wittrock, Ulrich

2005-01-01

This book treats the development and application of adaptive optics for industry and medicine. The contributions describe recently developed components for adaptive-optics systems such as deformable mirrors, wavefront sensors, and mirror drivers as well as complete adaptive optical systems and their applications in industry and medicine. Applications range from laser-beam forming and adaptive aberration correction for high-power lasers to retinal imaging in ophthalmology. The contributions are based on presentations made at the 4th International Workshop on Adaptive Optics in Industry and Medicine which took place in Münster, Germany, in October 2003. This highly successful series of workshops on adaptive optics started in 1997 and continues with the 5th workshop in Beijing in 2005.

4th International Conference on Power Transmissions

CERN Document Server

2013-01-01

This books contains the Proceedings of the 4th International Conference on Power Transmissions, that was held in Sinaia, Romania from June 20 -23, 2012. Power Transmissions is a very complex and multi-disciplinary scientific field of Mechanical Engineering that covers the different types of transmissions (mechanical, hydraulic, pneumatic) as well as all the machine elements involved, such as gears, bearings, shafts, couplings and a lot more. It concerns not only their basic theory but also their design, analysis, testing, application and maintenance. The requirements set to modern power transmissions are really tough to meet: They need to be more efficient, stronger, smaller, noiseless, easier to produce and to cost less. There is a strong demand to become easier in operation and maintenance, or even automatic and in maintenance-free. Last but not least, they should be easily recycled and respect the environment. Joint efforts of specialists from both academia and industry can significantly contribute to fulf...

Nondestructive testing standards and the ASME code

International Nuclear Information System (INIS)

Spanner, J.C.

1991-04-01

Nondestructive testing (NDT) requirements and standards are an important part of the ASME Boiler and Pressure Vessel Code. In this paper, the evolution of these requirements and standards is reviewed in the context of the unique technical and legal stature of the ASME Code. The coherent and consistent manner by which the ASME Code rules are organized is described, and the interrelationship between the various ASME Code sections, the piping codes, and the ASTM Standards is discussed. Significant changes occurred in ASME Sections 5 and 11 during the 1980s, and these are highlighted along with projections and comments regarding future trends and changes in these important documents. 4 refs., 8 tabs

ASME nuclear codes and standards: Scope of coverage and current initiatives

International Nuclear Information System (INIS)

Eisenberg, G. M.

1995-01-01

The objective of this paper is to address the broad scope of coverage of nuclear codes, standards and guides produced and administered by the American Society of Mechanical Engineers (ASME). Background information is provided regarding the evolution of the present activities. Details are provided on current initiatives intended to permit ASME to meet the needs of a changing nuclear industry on a worldwide scale. During the early years of commercial nuclear power, ASME produced a code for the construction of nuclear vessels used in the reactor coolant pressure boundary, containment and auxiliary systems. In response to industry growth, ASME Code coverage soon broadened to include rules for construction of other nuclear components, and inservice inspection of nuclear reactor coolant systems. In the years following this, the scope of ASME nuclear codes, standards and guides has been broadened significantly to include air cleaning activities for nuclear power reactors, operation and maintenance of nuclear power plants, quality assurance programs, cranes for nuclear facilities, qualification of mechanical equipment, and concrete reactor vessels and containments. ASME focuses on globalization of its codes, standards and guides by encouraging and promoting their use in the international community and by actively seeking participation of international members on its technical and supervisory committees and in accreditation activities. Details are provided on current international representation. Initiatives are underway to separate the technical requirements from administrative and enforcement requirements, to convert to hard metric units, to provide for non-U. S. materials, and to provide for translations into non-English languages. ASME activity as an accredited ISO 9000 registrar for suppliers of mechanical equipment is described. Rules are being developed for construction of containment systems for nuclear spent fuel and high-level waste transport packagings. Intensive

4. mednarodna znanstvena konferenca Management - teorija in praksa = 4th international conference Management Theory and Practice

Directory of Open Access Journals (Sweden)

Ana Arzenšek

2009-06-01

Full Text Available At the beginning of April 2009 the second largest city of Estonia was host to the 4th international conference Management Theory and Practice. The thematic emphasis of this year’s conference was Synergy in Organisations. The conference is biannually organised by the Institute of Business Administration of the University of Tartu, Faculty of Economics and Business Administration. In a year of innovation, special attention was given to creativity and innovation in management. Altogether, 40 papers were presented and more than 50 participants participated in the conference. The next, 5th conference, will take place in 2011.

NIST/ASME Steam Properties Database

Science.gov (United States)

SRD 10 NIST/ASME Steam Properties Database (PC database for purchase)   Based upon the International Association for the Properties of Water and Steam (IAPWS) 1995 formulation for the thermodynamic properties of water and the most recent IAPWS formulations for transport and other properties, this updated version provides water properties over a wide range of conditions according to the accepted international standards.

PREFACE: 4th International Conference on Mathematical Modeling in Physical Sciences (IC-MSquare2015)

Science.gov (United States)

Vlachos, Dimitrios; Vagenas, Elias C.

2015-09-01

The 4th International Conference on Mathematical Modeling in Physical Sciences (IC-MSQUARE) took place in Mykonos, Greece, from Friday 5th June to Monday 8th June 2015. The Conference was attended by more than 150 participants and hosted about 200 oral, poster, and virtual presentations. There were more than 600 pre-registered authors. The 4th IC-MSQUARE consisted of different and diverging workshops and thus covered various research fields where Mathematical Modeling is used, such as Theoretical/Mathematical Physics, Neutrino Physics, Non-Integrable Systems, Dynamical Systems, Computational Nanoscience, Biological Physics, Computational Biomechanics, Complex Networks, Stochastic Modeling, Fractional Statistics, DNA Dynamics, Macroeconomics etc. The scientific program was rather intense as after the Keynote and Invited Talks in the morning, three parallel oral and one poster session were running every day. However, according to all attendees, the program was excellent with a high quality of talks creating an innovative and productive scientific environment for all attendees. We would like to thank the Keynote Speaker and the Invited Speakers for their significant contribution to IC-MSQUARE. We also would like to thank the Members of the International Advisory and Scientific Committees as well as the Members of the Organizing Committee.

A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology.

Science.gov (United States)

Grassberger, M; Baumruker, T; Enz, A; Hiestand, P; Hultsch, T; Kalthoff, F; Schuler, W; Schulz, M; Werner, F J; Winiski, A; Wolff, B; Zenke, G

1999-08-01

SDZ ASM 981, a novel ascomycin macrolactam derivative, has high anti-inflammatory activity in animal models of allergic contact dermatitis and shows clinical efficacy in atopic dermatitis, allergic contact dermatitis and psoriasis, after topical application. Here we report on the in vitro activities of this promising new drug. SDZ ASM 981 inhibits the proliferation of human T cells after antigen-specific or non-specific stimulation. It downregulates the production of Th1 [interleukin (IL)-2, interferon-gamma] and Th2 (IL-4, IL-10) type cytokines after antigen-specific stimulation of a human T-helper cell clone isolated from the skin of an atopic dermatitis patient. SDZ ASM 981 inhibits the phorbol myristate acetate/phytohaemagglutinin-stimulated transcription of a reporter gene coupled to the human IL-2 promoter in the human T-cell line Jurkat and the IgE/antigen-mediated transcription of a reporter gene coupled to the human tumour necrosis factor (TNF)-alpha promoter in the murine mast-cell line CPII. It does not, however, affect the human TNF-alpha promoter controlled transcription of a reporter gene in a murine dendritic cell line (DC18 RGA) after stimulation via the FcgammaRIII receptor. SDZ ASM 981 also prevents the release of preformed pro-inflammatory mediators from mast cells, as shown in the murine cell line CPII after stimulation with IgE/antigen. In summary, these results demonstrate that SDZ ASM 981 is a specific inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro.

4th International Conference on Applied Computing and Information Technology

CERN Document Server

2017-01-01

This edited book presents scientific results of the 4th International Conference on Applied Computing and Information Technology (ACIT 2016) which was held on December 12–14, 2016 in Las Vegas, USA. The aim of this conference was to bring together researchers and scientists, businessmen and entrepreneurs, teachers, engineers, computer users, and students to discuss the numerous fields of computer science and to share their experiences and exchange new ideas and information in a meaningful way. The aim of this conference was also to bring out the research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them. The conference organizers selected the best papers from those papers accepted for presentation at the conference. The papers were chosen based on review scores submitted by members of the Program Committee, and underwent further rigorous rounds of review. Th...

ASME Code Efforts Supporting HTGRs

Energy Technology Data Exchange (ETDEWEB)

D.K. Morton

2012-09-01

In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

ASME Code Efforts Supporting HTGRs

Energy Technology Data Exchange (ETDEWEB)

D.K. Morton

2011-09-01

In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

4th International Conference on Sustainable Automotive Technologies

CERN Document Server

Wellnitz, Jörg; Leary, Martin; Koopmans, Lucien

2012-01-01

The book on Sustainable Automotive Technologies aims to draw special attention to the research and practice focused on new technologies and approaches capable of meeting the challenges to sustainable mobility. In particular, the book features incremental and radical technical advancements that are able to meet social, economic and environmental targets in both local and global contexts. These include original solutions to the problems of pollution and congestion, vehicle and public safety, sustainable vehicle design and manufacture, new structures and materials, new power-train technologies and vehicle concepts. In addition to vehicle technologies, the book is also concerned with the broader systemic issues such as sustainable supply chain systems, integrated logistics and telematics, and end-of-life vehicle management. It captures selected peer reviewed papers accepted for presentation at the 4th International Conference on Sustainable Automotive Technologies, ICSAT2012, held at the RMIT, Melbourne, Australi...

4th International Conference on Computer Engineering and Networks

CERN Document Server

2015-01-01

This book aims to examine innovation in the fields of computer engineering and networking. The book covers important emerging topics in computer engineering and networking, and it will help researchers and engineers improve their knowledge of state-of-art in related areas. The book presents papers from the 4th International Conference on Computer Engineering and Networks (CENet2014) held July 19-20, 2014 in Shanghai, China.  ·       Covers emerging topics for computer engineering and networking ·       Discusses how to improve productivity by using the latest advanced technologies ·       Examines innovation in the fields of computer engineering and networking  

Proceedings of the Seventh International Conference on Educational Data Mining (EDM) (7th, London, United Kingdom, July 4-7, 2014)

Science.gov (United States)

Stamper, John, Ed.; Pardos, Zachary, Ed.; Mavrikis, Manolis, Ed.; McLaren, Bruce M., Ed.

2014-01-01

The 7th International Conference on Education Data Mining held on July 4th-7th, 2014, at the Institute of Education, London, UK is the leading international forum for high-quality research that mines large data sets in order to answer educational research questions that shed light on the learning process. These data sets may come from the traces…

4th International Conference on Soft Computing for Problem Solving

CERN Document Server

Deep, Kusum; Pant, Millie; Bansal, Jagdish; Nagar, Atulya

2015-01-01

This two volume book is based on the research papers presented at the 4th International Conference on Soft Computing for Problem Solving (SocProS 2014) and covers a variety of topics, including mathematical modelling, image processing, optimization methods, swarm intelligence, evolutionary algorithms, fuzzy logic, neural networks, forecasting, medical and healthcare, data mining, etc. Mainly the emphasis is on Soft Computing and its applications in diverse areas. The prime objective of this book is to familiarize the reader with the latest scientific developments in various fields of Science, Engineering and Technology and is directed to the researchers and scientists engaged in various real-world applications of ‘Soft Computing’.

ASME power test code ptc 4.1 for steam generators; Codigo de pruebas de potencia ASME ptc 4.1 para generadores de vapor

Energy Technology Data Exchange (ETDEWEB)

Plauchu Alcantara, Jorge Alberto [Plauchu Consultores, Morelia, Michoacan (Mexico)

2001-07-01

This presentation is oriented towards those who in this subject have experience in the design and equipment specification, plant projects, factory and field testing, operation or result analyses. An important fraction of the national energy supply, approximately 13%, is applied to the steam generation in the different aspects of the industrial activity, in the electrical industry of public service and in the commercial and services sector. The development of the national programs of energy efficiency verifies this when dedicating to this use of the energy important projects, some of them with support of the USAID. The measurement of the energy utilization or the efficiency of steam generators (or boilers) is made applying some procedure agreed by the parts and the one of greater acceptance and best known in Mexico and internationally is the ASME Power Test Code PTC 4.1 for Steam Generators. The purpose and formality in the determination of efficiency and of steam generation capacity behavior, thermal basic regime or fulfillment of guarantees, radically changes the exigencies of strict attachment to the PTC 4.1 This definition will determine the importance of the test method selected, the deviations and convened exceptions, the influence of the precision and the measurement errors, the consideration of auxiliary equipment, etc. An interpretation or incorrect application of the Test Code has lead and will lead to results and nonreliable decisions. [Spanish] Esta exposicion se orienta a quienes en este tema cuenta con experiencia en diseno y especificacion de equipo, proyecto de planta, pruebas en fabrica y campo, operacion o analisis de resultados. Una fraccion importante de la oferta nacional de energia, 13% aproximadamente, se aplica a la generacion de vapor en diferentes giros de actividad industrial, en la industria electrica, de servicio publico y en el sector de servicios y comercial. El desarrollo de los programas nacionales de eficiencia energetica comprueba

4th International Conference on Software Process Improvement

CERN Document Server

Muñoz, Mirna; Rocha, Álvaro; Calvo-Manzano, Jose

2016-01-01

This book contains a selection of papers from The 2015 International Conference on Software Process Improvement (CIMPS’15), held between the 28th and 30th of October in Mazatlán, Sinaloa, México. The CIMPS’15 is a global forum for researchers and practitioners that present and discuss the most recent innovations, trends, results, experiences and concerns in the several perspectives of Software Engineering with clear relationship but not limited to software processes, Security in Information and Communication Technology and Big Data Field. The main topics covered are: Organizational Models, Standards and Methodologies, Knowledge Management, Software Systems, Applications and Tools, Information and Communication Technologies and Processes in non-software domains (Mining, automotive, aerospace, business, health care, manufacturing, etc.) with a demonstrated relationship to software process challenges.

International Workshop on Detection, Classification and Localization of Marine Mammals Using Passive Acoustics (4th). International Workshop on Density Estimation of Marine Mammals Using Passive Acoustics (1st)

Science.gov (United States)

2009-09-13

Università degli Studi di Pavia Dipartimento di Biologia Animale Centro Interdisciplinare di Bioacustica e Ricerche Ambientali 4th International...Dipartimento di Biologia Animale Centro Interdisciplinare di Bioacustica e Ricerche Ambientali 4th International Workshop on Detection, Classification...mail: gianni.pavan@unipv.it ORGANIZED BY: Università degli Studi di Pavia - Dipartimento di Biologia Animale CIBRA CENTRO INTERDISCIPLINARE DI

Meeting the difficulties of an ASME calibration for pipe welds

Energy Technology Data Exchange (ETDEWEB)

Ginzel, E., E-mail: eginzel@mri.on.ca [Materials Research Inst., Waterloo, Ontario (Canada); Ginzel, R.; Buchholz, J., E-mail: rginzel@eclipsescientific.com [Eclipse Scientific, Waterloo, Ontario (Canada)

2013-11-15

The American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel code Section V deals with Non-Destructive Testing (NDT). In North America the use of ASME Sec. V is not always limited to just ASME regulated projects. Even such seemingly unrelated Standards as CSA Z662 (the Canadian construction standard for Oil and Gas Pipeline Systems) references this document for some aspects of the NDT. ASME has several codes that are dedicated to piping welds, for example ASME 31.1, 31.3 and 31.8. All of them reference back to ASME Section V Article 4 for the accepted techniques to use when UT is the examination option, but sometimes ASME is not very helpful. As they try to leave options open in one area they close the doors in others, or so it seems when reading the clauses as mandatory where you see the word 'shall'. This paper will attempt to layout the issues with pipe weld inspections as per Article 4, 2011 edition. Like all other codes and standards, ASME is a regulated standard that is regularly reviewed and updated, and one must be careful to reference the year of the edition being used. For the purposes of this paper we have used the 2010/11 edition. (author)

Meeting the difficulties of an ASME calibration for pipe welds

International Nuclear Information System (INIS)

Ginzel, E.; Ginzel, R.; Buchholz, J.

2013-01-01

The American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel code Section V deals with Non-Destructive Testing (NDT). In North America the use of ASME Sec. V is not always limited to just ASME regulated projects. Even such seemingly unrelated Standards as CSA Z662 (the Canadian construction standard for Oil and Gas Pipeline Systems) references this document for some aspects of the NDT. ASME has several codes that are dedicated to piping welds, for example ASME 31.1, 31.3 and 31.8. All of them reference back to ASME Section V Article 4 for the accepted techniques to use when UT is the examination option, but sometimes ASME is not very helpful. As they try to leave options open in one area they close the doors in others, or so it seems when reading the clauses as mandatory where you see the word 'shall'. This paper will attempt to layout the issues with pipe weld inspections as per Article 4, 2011 edition. Like all other codes and standards, ASME is a regulated standard that is regularly reviewed and updated, and one must be careful to reference the year of the edition being used. For the purposes of this paper we have used the 2010/11 edition. (author)

Blast Mitigation Sea Analysis - Evaluation of Lumbar Compression Data Trends in 5th Percentile Female Anthropomorphic Test Device Performance Compared to 50th Percentile Male Anthropomorphic Test Device in Drop Tower Testing

Science.gov (United States)

2016-08-21

Kelly Bosch, PE Proceedings of the ASME 2016 International Design Engineering Technical Conferences & Computers and Information in Engineering...imparted on the occupant • Ideal EA device would reduce peak load and duration to reduce injury probability 5th Percentile Female – 200 g Pulse

Thermal expansion studies on Th(MoO4)2, Na2Th(MoO4)3 and Na4Th(MoO4)4

International Nuclear Information System (INIS)

Keskar, Meera; Krishnan, K.; Dahale, N.D.

2008-01-01

Thermal expansion behavior of Th(MoO 4 ) 2 , Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 was studied under vacuum in the temperature range of 298-1123 K by high temperature X-ray diffractometer. Th(MoO 4 ) 2 was synthesized by reacting ThO 2 with 2 mol of MoO 3 , at 1073 K in air and Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were prepared by reacting Th(MoO 4 ) 2 with 1 and 2 mol of Na 2 MoO 4 , respectively at 873 K in air. The XRD data of Th(MoO 4 ) 2 was indexed on orthorhombic system where as XRD data of Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were indexed on tetragonal system. The lattice parameters and cell volume of all the three compounds, fit into polynomial expression with respect to temperature, showed positive thermal expansion (PTE) up to 1123 K. The average value of thermal expansion coefficients for Th(MoO 4 ) 2 , Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were determined from the high temperature data

4th International Conference on Frontiers in Global Optimization

CERN Document Server

Pardalos, Panos

2004-01-01

Global Optimization has emerged as one of the most exciting new areas of mathematical programming. Global optimization has received a wide attraction from many fields in the past few years, due to the success of new algorithms for addressing previously intractable problems from diverse areas such as computational chemistry and biology, biomedicine, structural optimization, computer sciences, operations research, economics, and engineering design and control. This book contains refereed invited papers submitted at the 4th international confer­ ence on Frontiers in Global Optimization held at Santorini, Greece during June 8-12, 2003. Santorini is one of the few sites of Greece, with wild beauty created by the explosion of a volcano which is in the middle of the gulf of the island. The mystic landscape with its numerous mult-extrema, was an inspiring location particularly for researchers working on global optimization. The three previous conferences on "Recent Advances in Global Opti­ mization", "State-of-the-...

Book of abstracts: International Conference on Smart Energy Systems and 4th Generation District Heating

DEFF Research Database (Denmark)

, which takes a sole focus on the electricity sector, the smart energy systems approach includes the entire energy system in its identification of suitable energy infrastructure designs and operation strategies. Focusing solely on the smart electricity grid often leads to the definition of transmission......It is a great pleasure to welcome you to the first International Conference on Smart Energy Systems and 4th Generation District Heating at Aalborg University, Copenhagen Campus on 25-26 August 2015. The conference is organised by the 4DH Strategic Research Centre in collaboration with Aalborg...... University and offers more than 70 presentations in 3 parallel sessions with more than 180 participants from 25 countries around the world. The aim is to present and discuss scientific findings and industrial experiences related to the development of Smart Energy Systems and future 4th Generation District...

Accelerator System Model (ASM) user manual with physics and engineering model documentation. ASM version 1.0

International Nuclear Information System (INIS)

1993-07-01

The Accelerator System Model (ASM) is a computer program developed to model proton radiofrequency accelerators and to carry out system level trade studies. The ASM FORTRAN subroutines are incorporated into an intuitive graphical user interface which provides for the open-quotes constructionclose quotes of the accelerator in a window on the computer screen. The interface is based on the Shell for Particle Accelerator Related Codes (SPARC) software technology written for the Macintosh operating system in the C programming language. This User Manual describes the operation and use of the ASM application within the SPARC interface. The Appendix provides a detailed description of the physics and engineering models used in ASM. ASM Version 1.0 is joint project of G. H. Gillespie Associates, Inc. and the Accelerator Technology (AT) Division of the Los Alamos National Laboratory. Neither the ASM Version 1.0 software nor this ASM Documentation may be reproduced without the expressed written consent of both the Los Alamos National Laboratory and G. H. Gillespie Associates, Inc

Application of ASME code AG-1 to YGN 3 ampersand 4 plants, South Korea

International Nuclear Information System (INIS)

Kim, Y.K.; Porco, R.D.; York, Y.D.

1993-01-01

Yonggwang Nuclear Power Plant Units 3 ampersand 4 are located on the southwestern coast of South Korea on the Yellow Sea. The plant is owned by Korea Electric Power Corp. (KEPCO), with the engineering being performed by Korea Power Engineering Co., Inc. (KOPEC) and Sargent and Lundy under a technology transfer agreement. The plants are both 950 Megawatt (electric) pressurized water reactors of US design. Under contract to KEPCO, Korea Heavy Industries and Construction Co., Ltd. and Ellis and Watts, Division of Dynamics Corporation of America, Batavia, Ohio, supplied major components to the YGN plants in compliance to ASME AG-1. These components included safety related Air Cleaning Units, Reactor containment Fan Cooler Units, Air Handling Units, Cubicle Coolers, Duct Electric Heaters, and fans. This paper details the extent of applicability of ASME Code AG-1 to the specific equipment, description of the equipment, conformance, testing, and design required. The paper also discusses the problems encountered in implementing ASME AG-1, working around Code sections that were not complete at contract inception, conflicts in project documents and related problems. Also discussed are the logistics problems, material availability, and quality assurance aspects complicating the applications of ASME AG-1, due to the required Korean content for some components. Based on successfully supplying the equipment referenced above, it has been concluded that AG-1 is a working document and can be successfully implemented. It provides the requirements necessary for performance, design, construction, acceptance testing, and quality assurance of equipment used as components in nuclear air and gas treatment systems in nuclear facilities. The paper also addresses lessons learned and aspects of mixing US design and US built components in Korean built assemblies

A Comparison of the Variability of the Symbiotic X-ray Binaries GX 1+4, 4U 1954+31, and 4U 1700+24 from Swift/BAT and RXTE/ASM Observations

Science.gov (United States)

Corbet, R. H. D.; Sokoloski, J. L.; Mukai, K.; Markwardt, C. B.; Tueller, J.

2007-01-01

We present an analysis of the X-ray variability of three symbiotic X-ray binaries, GX 1+4, 4U 1700+24, and 4U 1954+31, using observations made with the Swift Burst Alert Telescope (BAT) and the Rossi X-ray Timing Explorer (RXTE) All-Sky Monitor (ASM). Observations of 4U 1954+31 with the Swift BAT show modulation at a period near 5 hours. Models to explain this modulation are discussed including the presence of an exceptionally slow X-ray pulsar in the system and accretion instabilities. We conclude that the most likely interpretation is that 4U 1954+31 contains one of the slowest known X-ray pulsars. Unlike 4U 1954+31, neither GX 1+4 nor 4U 1700+24 show any evidence for modulation on a timescale of hours. An analysis of the RXTE ASM light curves of GX l+4, 4U 1700+24, and 4U 1954+31 does not show the presence of periodic modulation in any source, although there is considerable variability on long timescales for all three sources. There is no modulation in GX 1+4 on either the optical 1161 day orbital period or a previously reported 304 day X-ray period. For 4U 1700+24 we do not confirm the 404 day period previously proposed for this source from a shorter duration ASM light curve.

4th International Conference on Structural Nonlinear Dynamics and Diagnosis

CERN Document Server

2018-01-01

This book presents contributions on the most active lines of recent advanced research in the field of nonlinear mechanics and physics selected from the 4th International Conference on Structural Nonlinear Dynamics and Diagnosis. It includes fifteen chapters by outstanding scientists, covering various aspects of applications, including road tanker dynamics and stability, simulation of abrasive wear, energy harvesting, modeling and analysis of flexoelectric nanoactuator, periodic Fermi–Pasta–Ulam problems, nonlinear stability in Hamiltonian systems, nonlinear dynamics of rotating composites, nonlinear vibrations of a shallow arch, extreme pulse dynamics in mode-locked lasers, localized structures in a photonic crystal fiber resonator, nonlinear stochastic dynamics, linearization of nonlinear resonances, treatment of a linear delay differential equation, and fractional nonlinear damping. It appeals to a wide range of experts in the field of structural nonlinear dynamics and offers researchers and engineers a...

76 FR 36231 - American Society of Mechanical Engineers (ASME) Codes and New and Revised ASME Code Cases

Science.gov (United States)

2011-06-21

...The NRC is amending its regulations to incorporate by reference the 2005 Addenda (July 1, 2005) and 2006 Addenda (July 1, 2006) to the 2004 ASME Boiler and Pressure Vessel Code, Section III, Division 1; 2007 ASME Boiler and Pressure Vessel Code, Section III, Division 1, 2007 Edition (July 1, 2007), with 2008a Addenda (July 1, 2008); 2005 Addenda (July 1, 2005) and 2006 Addenda (July 1, 2006) to the 2004 ASME Boiler and Pressure Vessel Code, Section XI, Division 1; 2007 ASME Boiler and Pressure Vessel Code, Section XI, Division 1, 2007 Edition (July 1, 2007), with 2008a Addenda (July 1, 2008); and 2005 Addenda, ASME OMa Code-2005 (approved July 8, 2005) and 2006 Addenda, ASME OMb Code-2006 (approved July 6, 2006) to the 2004 ASME Code for Operation and Maintenance of Nuclear Power Plants (OM Code). The NRC is also incorporating by reference (with conditions on their use) ASME Boiler and Pressure Vessel Code Case N-722-1, ``Additional Examinations for PWR Pressure Retaining Welds in Class 1 Components Fabricated with Alloy 600/82/182 Materials, Section XI, Division 1,'' Supplement 8, ASME approval date: January 26, 2009, and ASME Boiler and Pressure Vessel Code Case N-770-1, ``Alternative Examination Requirements and Acceptance Standards for Class 1 PWR Piping and Vessel Nozzle Butt Welds Fabricated With UNS N06082 or UNS W86182 Weld Filler Material With or Without Application of Listed Mitigation Activities, Section XI, Division 1,'' ASME approval date: December 25, 2009.

Accelerator System Model (ASM) user manual with physics and engineering model documentation. ASM version 1.0

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-07-01

The Accelerator System Model (ASM) is a computer program developed to model proton radiofrequency accelerators and to carry out system level trade studies. The ASM FORTRAN subroutines are incorporated into an intuitive graphical user interface which provides for the {open_quotes}construction{close_quotes} of the accelerator in a window on the computer screen. The interface is based on the Shell for Particle Accelerator Related Codes (SPARC) software technology written for the Macintosh operating system in the C programming language. This User Manual describes the operation and use of the ASM application within the SPARC interface. The Appendix provides a detailed description of the physics and engineering models used in ASM. ASM Version 1.0 is joint project of G. H. Gillespie Associates, Inc. and the Accelerator Technology (AT) Division of the Los Alamos National Laboratory. Neither the ASM Version 1.0 software nor this ASM Documentation may be reproduced without the expressed written consent of both the Los Alamos National Laboratory and G. H. Gillespie Associates, Inc.

4th International Conference in Software Engineering for Defence Applications

CERN Document Server

Sillitti, Alberto; Succi, Giancarlo; Messina, Angelo

2016-01-01

This book presents high-quality original contributions on new software engineering models, approaches, methods, and tools and their evaluation in the context of defence and security applications. In addition, important business and economic aspects are discussed, with a particular focus on cost/benefit analysis, new business models, organizational evolution, and business intelligence systems. The contents are based on presentations delivered at SEDA 2015, the 4th International Conference in Software Engineering for Defence Applications, which was held in Rome, Italy, in May 2015. This conference series represents a targeted response to the growing need for research that reports and debates the practical implications of software engineering within the defence environment and also for software performance evaluation in real settings through controlled experiments as well as case and field studies. The book will appeal to all with an interest in modeling, managing, and implementing defence-related software devel...

4th International Conference on Robot Intelligence Technology and Applications

CERN Document Server

Karray, Fakhri; Jo, Jun; Sincak, Peter; Myung, Hyun

2017-01-01

This book covers all aspects of robot intelligence from perception at sensor level and reasoning at cognitive level to behavior planning at execution level for each low level segment of the machine. It also presents the technologies for cognitive reasoning, social interaction with humans, behavior generation, ability to cooperate with other robots, ambience awareness, and an artificial genome that can be passed on to other robots. These technologies are to materialize cognitive intelligence, social intelligence, behavioral intelligence, collective intelligence, ambient intelligence and genetic intelligence. The book aims at serving researchers and practitioners with a timely dissemination of the recent progress on robot intelligence technology and its applications, based on a collection of papers presented at the 4th International Conference on Robot Intelligence Technology and Applications (RiTA), held in Bucheon, Korea, December 14 - 16, 2015. For better readability, this edition has the total of 49 article...

Passport of global nuclear business. ASME code certificate acquirement and inspection practices

International Nuclear Information System (INIS)

Kawabata, Hiroyuki; Terajima, Makoto; Anami, Kazuhiro

2010-01-01

There are possibilities of Japanese nuclear industries to participate in global business such as new and additional construction of nuclear power plants in US and also Asian and other developing countries in the world. It is requisite to acquire ASME code certificate for global business participation, just as passport. This article consists of five papers on present status of ASME code certificate acquirement and inspection practices of nuclear components vendors in the area of Japanese nuclear business. Activities of JSME Committee on Power Generation Facility Codes to make JSME codes corresponded to ASME nuclear codes and standards for their international deployment are also described. (T. Tanaka)

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice.

Science.gov (United States)

Li, Xiang; Han, Wei-Qing; Boini, Krishna M; Xia, Min; Zhang, Yang; Li, Pin-Lan

2013-01-01

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptor, death receptor 4 (DR4), have been implicated in the development of endothelial dysfunction and atherosclerosis. However, the signaling mechanism mediating DR4 activation leading to endothelial injury remains unclear. We recently demonstrated that ceramide production via hydrolysis of membrane sphingomyelin by acid sphingomyelinase (ASM) results in membrane raft (MR) clustering and the formation of important redox signaling platforms, which play a crucial role in amplifying redox signaling in endothelial cells leading to endothelial dysfunction. The present study aims to investigate whether TRAIL triggers MR clustering via lysosome fusion and ASM activation, thereby conducting transmembrane redox signaling and changing endothelial function. Using confocal microscopy, we found that TRAIL induced MR clustering and co-localized with DR4 in coronary arterial endothelial cells (CAECs) isolated from wild-type (Smpd1 (+/+)) mice. Furthermore, TRAIL triggered ASM translocation, ceramide production, and NADPH oxidase aggregation in MR clusters in Smpd1 ( +/+ ) CAECs, whereas these observations were not found in Smpd1 (-/-) CAECs. Moreover, ASM deficiency reduced TRAIL-induced O(2) (-[Symbol: see text]) production in CAECs and abolished TRAIL-induced impairment on endothelium-dependent vasodilation in small resistance arteries. By measuring fluorescence resonance energy transfer, we found that Lamp-1 (lysosome membrane marker protein) and ganglioside G(M1) (MR marker) were trafficking together in Smpd1 (+/+) CAECs, which was absent in Smpd1 (-/-) CAECs. Consistently, fluorescence imaging of living cells with specific lysosome probes demonstrated that TRAIL-induced lysosome fusion with membrane was also absent in Smpd1 (-/-) CAECs. Taken together, these results suggest that ASM is essential for TRAIL-induced lysosomal trafficking, membrane fusion and formation of MR redox signaling platforms

Selected Lectures of the 13th International Workshop on Neonatology; Cagliari (Italy); October 25th-28th, 2017

OpenAIRE

--- Various Authors

2017-01-01

Selected Lectures of the 13th International Workshop on Neonatology • The power of Epigenetics • Twins: identical but different • Cagliari (Italy) • October 25th-28th, 2017LECT 1. ASPHYXIA IN THE THIRD MILLENNIUM: FROM VIRGINIA APGAR TO METABOLOMICS • O.D. SaugstadLECT 2. INTRAPARTUM FETAL MONITORING: WHERE ARE WE NOW? • D. Ayres-de-CamposLECT 3. THERAPEUTIC HYPOTHERMIA: REVISED IN­DI­CA­TIONS • E. SalibaLECT 4. ANTIBIOTICS PRESCRIPTION IN NEONATAL INTENSIVE CARE UNIT • G. DimitriouLECT 5. CH...

AIS ASM Operational Integration Plan

Science.gov (United States)

2013-08-01

Rack mount computer AIS Radio Interface Ethernet Switch 192.168.0.x Firewall Cable Modem 192.168.0.1 VTS Accred. Boundary AIS ASM Operational... AIS ASM Operational Integration Plan Distribution Statement A: Approved for public release; distribution is unlimited. August 2013 Report No...CD-D-07-15 AIS ASM Operational Integration Plan ii UNCLAS//Public | CG-926 R&DC | I. Gonin, et al. | Public August 2013 N O T I C

Regulatory Endorsement Activities for ASME Nuclear Codes and Standards

International Nuclear Information System (INIS)

West, Raymond A.

2006-01-01

The ASME Board on Nuclear Codes and Standards (BNCS) has formed a Task Group on Regulatory Endorsement (TG-RE) that is currently in discussions with the United States Nuclear Regulatory Commission (NRC) to look at suggestions and recommendations that can be used to help with the endorsement of new and revised ASME Nuclear Codes and Standards (NC and S). With the coming of new reactors in the USA in the very near future we need to look at both the regulations and all the ASME NC and S to determine where we need to make changes to support these new plants. At the same time it is important that we maintain our operating plants while addressing ageing management needs of our existing reactors. This is going to take new thinking, time, resources, and money. For all this to take place the regulations and requirements that we use must be clear concise and necessary for safety and to that end both the NRC and ASME are working together to make this happen. Because of the influence that the USA has in the world in dealing with these issues, this paper is written to inform the international nuclear engineering community about the issues and what actions are being addressed under this effort. (author)

CONAGT's place in ASME's centennial year

International Nuclear Information System (INIS)

Miller, W.H. Jr.

1985-01-01

A status report on ASME's Committee on Nuclear Air and Gas Treatment (CONAGT) is presented. This year ASME celebrates its centennial while CONAGT issues its first code sections covering fans, blowers, and refrigeration equipment. Significant code related CONAGT activities are covered as well as an explanation of CONAGT's place in the ASME organization

A comparative study for SMART steam generator sizing based on ASME and Russian standard

International Nuclear Information System (INIS)

Kim, Y. W.; Kim, J. I.; Jang, M. H.

2000-01-01

A systematic comparison of ASME and Russian standard with respect to the design of SMART steam generator has been carried out. Classification of allowable stress in the Russian standard is quite different from that of ASME. Allowable stress of Russian standard and stress intensity defined in ASME were compared for various steam generator tube material as a function of design temperature. Equations and methodology of determining the thickness for the important parts of steam generator have been analyzed. For the tube subjected to internal and/or external pressure, Russian standard use the same equation in the sizing of tube with different allowable stress. However, ASME use different equations with the same value of allowable stress intensity. The hydraulic test pressure of ASME was also compared with that of Russian standard. In general, hydraulic test pressure determined by Russian standard is higher since it considers difference between allowable stress of test temperature and that of design temperature

4th International Conference on Energy and Environment 2013 (ICEE 2013)

Science.gov (United States)

Chakrabarty, Chandan Kumar; Shamsuddin, Abd Halim Bin; Ahmad, Ibrahim Bin; Desa, Mohamed Nor Bin Mohamed; Din, Norashidah Bte Md; Bte Mohd, Lariyah; Hamid, Nasri A.; See, Ong Hang; Hafiz Nagi, Farrukh; Yong, Lee Choon; Pasupuleti, Jagadeesh; Mei, Goh Su; Abdullah, Fairuz Bin; Satgunam, Meenaloshini

2013-06-01

The 4th International Conference on Energy & Environment 2013 (ICEE2013) was organized by the Universiti Tenaga Nasional (UNITEN) to provide a platform for creating and sharing ideas among engineers, researchers, scientists, industrialists and students in sustainable green energy and technologies. The theme 'Shaping a Sustainable Future through Advancement in Green Energy Technology' is in line with the University's vision to be a leading global energy university that shapes a sustainable future. The general scopes of the conference are renewable energy, smart grid, green technology, energy policies and economics, sustainable green energy and environment, sustainable education, international cooperation and innovation and technology transfer. Five international keynote speakers delivered their speeches in specialized areas of green energy technology and sustainability. In addition, the conference highlights several special parallel sessions by notable invited presenters in their niche areas, which are: Hybrid Energy Power Quality & Distributed Energy Smart Grid Nuclear Power & Technologies Geohazard Management Greener Environment for Sustainability Advances in Computational Fluid Dynamics The research papers presented in ICEE2013 are included in this volume of IOP Conference Series: Earth and Environmental Science (EES). EES is abstracted and indexed in SCOPUS, GeoBase, GeoRef, Compendex, Inspec, Chemical Abstracts Service, NASA Astrophysics Data System, and International Nuclear Information System (INIS). With the comprehensive programme outline, the organizing committee hopes that the ICEE2013 was a notable intellectual sharing session for the research and academic community in Malaysia and regionally. The organizing committee expresses gratitude to the ICEE2013 delegates for their great support and contributions to the event.

The 13th international conference on scientometrics and informetrics

DEFF Research Database (Denmark)

Ocholla, Dennis; Ingwersen, Peter; Noyons, Ed

2012-01-01

The 13th International Conference on Scientometrics and Informetrics took place in Durban, South Africa from 4 to 7 July 2011, Ocholla and Ingwersen (2011). The meeting was organised under the auspices of the International Society for Scientometrics and Informetrics (ISSI) and by the ISSI 2011...

PREFACE: 4th International Conference on Safe Production and Use of Nanomaterials (Nanosafe2014)

Science.gov (United States)

Tardif, F.; Damlencourt, J.-F.; Schuster, F.; Gaultier, V.

2015-05-01

This volume contains a collection of contributions presented at the 4th International Conference on Safe Production and Use of Nanomaterials (NANOSAFE 2014) held in Grenoble, France, from 18th to 20th November 2014. The issues of fast progress in the field of Nanosafety are up to the potential benefits that nanotechnology can bring to mankind. Making more efficient - more sustainable - easier to share mineral resources, increasing the yields of new energy technologies, enabling drugs that act selectively and locally are just few examples of the wide range of nanomaterial applications that currently benefit humanity. Nevertheless, the dynamic development of nanomaterials requires the adhesion from the general public who rightly demand major progresses in Nanosafety as a prerequisite. This is our exciting responsibility and challenge! Following the successful outcome of the three past international conferences on safe production and use of nanomaterials: Nanosafe 2008, 2010 and 2012, the organizing committee has the pleasure to welcoming you again to Minatec, Grenoble with some of the most famous specialists in the field. This year, two new topics have been added dealing with the "New Application of Nanomaterials" and "Nano-responsible Development" in addition to the usual issues addressed in previous Nanosafe conferences such as Expology, Detection and Characterization, Toxicology, Environmental Interactions, Nanomaterials Release, Life Cycle Analysis, Regulation and Standardization, Risk Management. The debates in 2012 proved highly successful so this formula has been kept in 2014 with 3 round tables: Nano-Responsible Development, Risks and Benefits for the Environment, Toxicology Progress. In this 4th edition, there were more than 330 registered participants from 28 different countries including 160 oral presentation covering the whole Nanosafety issues in 12 sessions, satellite workshops and round tables. This high number of participants makes this edition one of

4th International Conference on Innovations in Bio-Inspired Computing and Applications

CERN Document Server

Krömer, Pavel; Snášel, Václav

2014-01-01

This volume of Advances in Intelligent Systems and Computing contains accepted papers presented at IBICA2013, the 4th International Conference on Innovations in Bio-inspired Computing and Applications. The aim of IBICA 2013 was to provide a platform for world research leaders and practitioners, to discuss the full spectrum of current theoretical developments, emerging technologies, and innovative applications of Bio-inspired Computing. Bio-inspired Computing is currently one of the most exciting research areas, and it is continuously demonstrating exceptional strength in solving complex real life problems. The main driving force of the conference is to further explore the intriguing potential of Bio-inspired Computing. IBICA 2013 was held in Ostrava, Czech Republic and hosted by the VSB - Technical University of Ostrava.

75 FR 24323 - American Society of Mechanical Engineers (ASME) Codes and New and Revised ASME Code Cases

Science.gov (United States)

2010-05-04

...The NRC proposes to amend its regulations to incorporate by reference the 2005 Addenda through 2008 Addenda of Section III, Division 1, and the 2005 Addenda through 2008 Addenda of Section XI, Division 1, of the ASME Boiler and Pressure Vessel Code (ASME B&PV Code); and the 2005 Addenda and 2006 Addenda of the ASME Code for Operation and Maintenance of Nuclear Power Plants (ASME OM Code). The NRC also proposes to incorporate by reference ASME Code Case N-722-1, ``Additional Examinations for PWR Pressure Retaining Welds in Class 1 Components Fabricated With Alloy 600/82/182 Materials Section XI, Division 1,'' and Code Case N-770, ``Alternative Examination Requirements and Acceptance Standards for Class 1 PWR [Pressurized- Water Reactor] Piping and Vessel Nozzle Butt Welds Fabricated with UNS N06082 or UNS W86182 Weld Filler Material with or without Application of Listed Mitigation Activities.''

4th International Conference on Frontiers in Intelligent Computing : Theory and Applications

CERN Document Server

Pal, Tandra; Kar, Samarjit; Satapathy, Suresh; Mandal, Jyotsna

2016-01-01

The proceedings of the 4th International Conference on Frontiers in Intelligent Computing: Theory and Applications 2015 (FICTA 2015) serves as the knowledge centre not only for scientists and researchers in the field of intelligent computing but also for students of post-graduate level in various engineering disciplines. The book covers a comprehensive overview of the theory, methods, applications and tools of Intelligent Computing. Researchers are now working in interdisciplinary areas and the proceedings of FICTA 2015 plays a major role to accumulate those significant works in one arena. The chapters included in the proceedings inculcates both theoretical as well as practical aspects of different areas like Nature Inspired Algorithms, Fuzzy Systems, Data Mining, Signal Processing, Image processing, Text Processing, Wireless Sensor Networks, Network Security and Cellular Automata. .

The ASME Code today -- Challenges, threats, opportunities

International Nuclear Information System (INIS)

Canonico, D.A.

1995-01-01

Since its modest beginning as a single volume in 1914 the ASME Code, or some of its parts, is recognized today in 48 of the United States and all providence's of Canada. The ASME Code today is composed of 25 books including two Code Case books. These books cover the new construction of boilers and pressure vessels and the new construction and In-Service-Inspection of Nuclear Power Plant components. The ASME accredits all manufacturers of boilers and pressure vessels built to the ASME Code. There are approximately 7650 symbol stamps issued throughout the world. Over 23% of the symbol stamps have been issued outside the USA and Canada. The challenge to the ASME Code is to be accepted as the world standard for pressure boundary components. There are activities underway to achieve that goal. The ASME Code is being revised to make it a more friendly document to entities outside of North America. To achieve that end there are specific tasks underway which are described here

SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis.

Science.gov (United States)

Luger, T; Van Leent, E J; Graeber, M; Hedgecock, S; Thurston, M; Kandra, A; Berth-Jones, J; Bjerke, J; Christophers, E; Knop, J; Knulst, A C; Morren, M; Morris, A; Reitamo, S; Roed-Petersen, J; Schoepf, E; Thestrup-Pedersen, K; Van Der Valk, P G; Bos, J D

2001-04-01

SDZ ASM 981 is a selective inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro. It is the first ascomycin macrolactam derivative under development for the treatment of inflammatory skin diseases. This study was designed to determine the safety and efficacy of SDZ ASM 981 cream at concentrations of 0.05%, 0.2%, 0.6% and 1.0% in the treatment of patients with atopic dermatitis and to select the concentration to be used in phase III studies. This was a double-blind, randomized, parallel-group, multicentre dose-finding study. A total of 260 patients were randomly assigned to treatment with SDZ ASM 981 cream at concentrations of 0.05%, 0.2%, 0.6%, or 1.0%, matching vehicle cream, or the internal control 0.1% betamethasone-17-valerate cream (BMV). Treatment was given twice daily for up to 3 weeks. A clear dose-response relationship for SDZ ASM 981 was evident, with 0.2%, 0.6% and 1.0% SDZ ASM 981 creams all being significantly more effective than vehicle (P = 0.041, 0.001 and 0.008, respectively) in terms of baseline to end-point changes in the Eczema Area Severity Index (EASI) and pruritus score. The 1.0% cream was the most effective SDZ ASM 981 concentration. BMV was more effective than the SDZ ASM 981 creams tested in this study. It appears that the efficacy plateau was not reached with the SDZ ASM 981 creams within 3 weeks treatment. SDZ ASM 981 was well tolerated. Burning or a feeling of warmth were the only adverse events reported more frequently in the 0.6% and 1.0% SDZ ASM 981 treatment groups than in the vehicle treatment group (42.9%, 48.9% and 34.9%, respectively). Few systemic adverse events were reported during the study (headache was the most frequent systemic event reported by 15 of 252 patients) and none was considered to be related to treatment. The local tolerability profile of the 1.0% cream was similar to that of the lower concentrations. 1.0% SDZ ASM 981 cream, which was shown to be safe, well tolerated and

Proceedings of the International Conference on Educational Data Mining (EDM) (4th, Eindhoven, the Netherlands, July 6-8, 2011)

Science.gov (United States)

Pechenizkiy, Mykola; Calders, Toon; Conati, Cristina; Ventura, Sebastian; Romero, Cristobal; Stamper, John

2011-01-01

The 4th International Conference on Educational Data Mining (EDM 2011) brings together researchers from computer science, education, psychology, psychometrics, and statistics to analyze large datasets to answer educational research questions. The conference, held in Eindhoven, The Netherlands, July 6-9, 2011, follows the three previous editions…

Probing the Mysteries of the X-Ray Binary 4U 1210-64 with ASM, MAXI and Suzaku

Science.gov (United States)

Coley, Joel B.; Corbet, R.; Mukai, K.; Pottschmidt, K.

2013-01-01

Optical and X-ray observations of 4U 1210-64 (1ES 1210-646) suggest that the source is a High Mass X-ray Binary (HMXB) probably powered by the Be mechanism. Data acquired by the RXTE All Sky Monitor (ASM), the ISS Monitor of All-sky X-ray Image (MAXI) and Suzaku provide a detailed temporal and spectral description of this poorly understood source. Long-term data produced by ASM and MAXI indicate that the source shows two distinct high and low states. A 6.7-day orbital period of the system was found in folded light curves produced by both ASM and MAXI. A two day Suzaku observation in Dec. 2010 took place during a transition from the minimum to the maximum of the folded light curve. The two day Suzaku observation reveals large variations in flux indicative of strong orbit to orbit variability. Flares in the Suzaku light curve can reach nearly 1.4 times the mean count rate. From a spectral analysis of the Suzaku data, emission lines in the Fe K alpha region were detected at 6.4 keV, 6.7 keV and 6.97 keV interpreted as FeI, FeXXV and FeXXVI. In addition, emission lines were observed at approximately 1.0 and 2.6 keV, corresponding to NeX and SXVI respectively. Thermal bremsstrahlung or power law models both modified by interstellar and partially covering absorption provide a good fit to the continuum data. This source is intriguing for these reasons: i) No pulse period was observed; ii) 6.7 day orbital period is much less than typical orbital periods seen in Be/X-ray Binaries; iii) The optical companion is a B5V--an unusual spectral class for an HMXB; iv) There are extended high and low X-ray states.

Proceedings of the 4th International Workshop on Tritium Effects in Plasma Facing Components

International Nuclear Information System (INIS)

Causey, R. A.

1999-01-01

The 4th International Workshop on Tritium Effects in Plasma Facing Components was held in Santa Fe, New Mexico on May 14-15, 1998. This workshop occurs every two years, and has previously been held in Livermore/California, Nagoya/Japan, and the JRC-Ispra Site in Italy. The purpose of the workshop is to gather researchers involved in the topic of tritium migration, retention, and recycling in materials used to line magnetic fusion reactor walls and provide a forum for presentation and discussions in this area. This document provides an overall summary of the workshop, the workshop agenda, a summary of the presentations, and a list of attendees

Meeting report on the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition.

Science.gov (United States)

Lories, Bram; Parijs, Ilse; Foster, Kevin R; Steenackers, Hans P

2017-08-14

The ASM Conference on Mechanisms of Interbacterial Cooperation and Competition was held in Washington DC, from 1 to 4 March 2017. The conference provided an international forum for sociomicrobiologists from different disciplines to present and discuss new findings. The meeting covered a wide range of topics, spanning molecular mechanisms, ecology, evolution, computation and manipulation of interbacterial interactions, and encompassed social communities in medicine, the natural environment, and industry. This report summarizes the presentations and emerging themes. Copyright © 2017 American Society for Microbiology.

Th biodistribution in internal contamination of animals

International Nuclear Information System (INIS)

Ciubotariu, M.; Danis, A.; Dumitrescu, G.; Cucu, M.

1999-01-01

Fissionable elements (U,Th) internal contamination have been studied using the fission track method as analysis method of the U and/or Th contaminant elements and Wistar-London breed rats as experiment animals. Different ways to obtain internal contaminations have been investigated: ingestion, inhalation, absorption by skin and through wounds. After the U internal contamination study was carried out, in this stage the Th internal contamination by ingestion is in progress. Using the identical aliquot parts of a solution calibrated in Th, corresponding to an Annual Limit Intake, three Wistar-London breed rats were contaminated. They were kept in normal life conditions and under permanent medical surveillance up to their sacrification. The animals were sacrificed at different time intervals after their contamination: 2 days, 7 days and 14 days, respectively. After the sacrification, their vital organs were sampled, weighed, calcined, re-weighed and finally analysed by track detection using the fission track micro-mappings technique. Also, their evacuations were sampled every 24 hours weighed, calcined and analysed in the same way as the vital organs. The Th fission track micro-mappings technique was used in the following conditions: - mica-muscovite as track detector pre-etched for fossil tracks 18 h in HF-40 per cent at room temperature; - the neutron irradiations were performed in the nuclear reactor VVR-S Bucharest at the neutron fluences of 3.10 15 - 2.10 16 fast neutrons/c m 2 ; - the visualization of the Th induced fission tracks were obtained by chemical etching in HF-40 per cent, 3 h at room temperature; - the Th track micro-mappings obtained in track detectors were studied by optical microscopy using a stereo microscope WILD M7S for ensemble study (X6-X31) and a binocular ZEISS JENA microscope for qualitative and quantitative studies (X150). The biological reference materials calibrated in Th were prepared in our laboratory using the calcined organs and the

Globalization of ASME Nuclear Codes and Standards

International Nuclear Information System (INIS)

Swayne, Rick; Erler, Bryan A.

2006-01-01

With the globalization of the nuclear industry, it is clear that the reactor suppliers are based in many countries around the world (such as United States, France, Japan, Canada, South Korea, South Africa) and they will be marketing their reactors to many countries around the world (such as US, China, South Korea, France, Canada, Finland, Taiwan). They will also be fabricating their components in many different countries around the world. With this situation, it is clear that the requirements of ASME Nuclear Codes and Standards need to be adjusted to accommodate the regulations, fabricating processes, and technology of various countries around the world. It is also very important for the American Society of Mechanical Engineers (ASME) to be able to assure that products meeting the applicable ASME Code requirements will provide the same level of safety and quality assurance as those products currently fabricated under the ASME accreditation process. To do this, many countries are in the process of establishing or changing their regulations, and it is important for ASME to interface with the appropriate organizations in those countries, in order to ensure there is effective use of ASME Codes and standards around the world. (authors)

Travel grant program for the IX International Congresses of Mycology and Bacteriology -- Final report

Energy Technology Data Exchange (ETDEWEB)

Granigan, Marion

2000-05-25

In 1999, the American Society for Microbiology (ASM) and the National Academy of Sciences' U.S. National Committee for the International Union of Microbiological Sciences (IUMS) jointly organized a competitive travel grant program to support the participation of U.S. scientists in the 9th International Congresses of the Bacteriological and Applied Microbiology, Mycology and Virology Divisions of the IUMS in Sydney, Australia, August 16-20, 1999. Funding was solicited for the program, and the ASM Minority and International Activities department administered the $40,000 raised. Travel grants in the amount of $2,000 were offered to U.S. investigators (citizens, including federal employees, and permanent residents working in the United States) in the early stages of their careers who planned to attend and present their research at the Congress. Teams of established and new investigators who applied jointly were eligible to received a combined $3,000 award. IUMS developed a questionnaire th at each applicant were required to complete and return, which asked each award recipient about their experience at the Congresses. Questionnaire results are included.

Inhibition of allergen-induced basophil activation by ASM-024, a nicotinic receptor ligand.

Science.gov (United States)

Watson, Brittany M; Oliveria, John Paul; Nusca, Graeme M; Smith, Steven G; Beaudin, Sue; Dua, Benny; Watson, Rick M; Assayag, Evelynne Israël; Cormier, Yvon F; Sehmi, Roma; Gauvreau, Gail M

2014-01-01

Nicotinic acetylcholine receptors (nAChRs) were identified on eosinophils and shown to regulate inflammatory responses, but nAChR expression on basophils has not been explored yet. We investigated surface receptor expression of nAChR α4, α7 and α1/α3/α5 subunits on basophils. Furthermore, we examined the effects of ASM-024, a synthetic nicotinic ligand, on in vitro anti-IgE and in vivo allergen-induced basophil activation. Basophils were enriched from the peripheral blood of allergic donors and the expression of nAChR subunits and muscarinic receptors was determined. Purified basophils were stimulated with anti-IgE in the presence of ASM-024 with or without muscarinic or nicotinic antagonists for the measurement of CD203c expression and histamine release. The effect of 9 days of treatment with 50 and 200 mg ASM-024 on basophil CD203c expression was examined in the blood of mild allergic asthmatics before and after allergen inhalation challenge. nAChR α4, α7 and α1/α3/α5 receptor subunit expression was detected on basophils. Stimulation of basophils with anti-IgE increased CD203c expression and histamine release, which was inhibited by ASM-024 (10(-5) to 10(-)(3) M, p ASM-024 was reversed in the presence of muscarinic and nicotinic antagonists. In subjects with mild asthma, ASM-024 inhalation significantly inhibited basophil CD203c expression measured 24 h after allergen challenge (p = 0.03). This study shows that ASM-024 inhibits IgE- and allergen-induced basophil activation through both nicotinic and muscarinic receptors, and suggests that ASM-024 may be an efficacious agent for modulating allergic asthma responses. © 2015 S. Karger AG, Basel.

9th International Symposium on Lactic Acid Bacteria

NARCIS (Netherlands)

Kuipers, Oscar P.; Poolman, Berend; Hugenholtz, Jeroen

What’s new in the field of lactic acid bacteria? The 9th International Symposium on Lactic Acid Bacteria (LAB9) will take place 31 August to 4 September 2008 in Egmond aan Zee, The Netherlands. Traditionally, the triannual LAB symposium focuses on the themes of genetics, physiology, and applications

Iterative and non-iterative solutions of engine flows using ASM and k-ε turbulence models

International Nuclear Information System (INIS)

Khaleghi, H.; Fallah, E.

2003-01-01

Various turbulent models are widely developed in order to make a good prediction of turbulence phenomena in different applications. The standard k-ε model shows a poor prediction for some applications. The Reynolds Stress Model (RSM) is expected to give a better prediction of turbulent characteristics, because a separate differential equation for each Reynolds stress component is solved in this model. In order to save both time and memory in this calculation a new Algebraic Stress Model (ASM) which was developed by Lumly et al in 1995 is used for calculations of flow characteristics in the internal combustion engine chamber. With using turbulent realizability principles, this model becomes a powerful and reliable turbulence model. In this paper the abilities of the model is examined in internal combustion engine flows. The results of ASM and k-ε models are compared with the experimental data. It is shown that the poor predictions of k-ε model are modified by ASM model. Also in this paper non-iterative PISO and iterative SIMPLE solution algorithms are compared. The results show that the PISO solution algorithm is the preferred and more efficient procedure in the calculation of internal combustion engine. (author)

U4+ spectroscopic properties in Dsub(2d) with ThCl4, UCl4 and ThSiO4

International Nuclear Information System (INIS)

Khan Malek, C.

1985-01-01

This thesis is concerned with the study of the electronic structure of the tetravalent actinide ions in solid state. The technique used was high resolution optical spectroscopy. We deal with the U 4+ ion (sf 2 ) in the monocrystals ThCl 4 , UCl 4 , and ThSiO 4 where the U 4+ ion is substituded for the Th 4+ ion by doping. Visible and infrared optical spectra were recorded between 300 and 4.2K. With these three compounds, it is possible to compare the influence of different environments of Dsub(2d) symmetry: real symmetry for U 4+ in UCl 4 and ThSiO 4 ; approximate symmetry in ThCl 4 , whose structure is incommensurate and modulated at low temperature. The fitting of the data was carried out by diagonalizing the hamiltonian which describes the interactions of the U 4+ ion in a crystal field with its environment. This fitting procedure led to a coherent set of spectroscopic parameters. The fluorescence of U 4+ was observed in ThCl 4 and ThSiO 4 and the effect of the incommensurate structure of ThCl 4 on the optical spectra was studied. The symmetry of the U 4+ sites was identified by site selective excitation experiments and a relationship between the incommensurate structure and the lifetime of U 4+ energy levels was found. In conclusion, the U 4+ energy levels in a relatively low crystal field were determined for compounds that have a similar coordination polyhedron about the actinide ion. The values for these energy levels were then compared to those of lanthanide and 3d elements [fr

Basic requirements of mechanical properties for nuclear pressure vessel materials in ASME-BPV code

International Nuclear Information System (INIS)

Ning Dong; Yao Weida

2011-01-01

The four basic aspects of strengths, ductility, toughness and fatigue strengths can be summarized for overall mechanical properties requirements of materials for nuclear pressure-retaining vessels in ASME-BPV code. These mechanical property indexes involve in the factors of melting, manufacture, delivery conditions, check or recheck for mechanical properties and chemical compositions, etc. and relate to degradation and damage accumulation during the use of materials. This paper specifically accounts for the basic requirements and theoretic basis of mechanical properties for nuclear pressure vessel materials in ASME-BPV code and states the internal mutual relationships among the four aspects of mechanical properties. This paper focuses on putting forward at several problems on mechanical properties of materials that shall be concerned about during design and manufacture for nuclear pressure vessels according to ASME-BPV code. (author)

Index to place of publication of ASME Papers, 1978--1988

International Nuclear Information System (INIS)

Youngen, G.K.

1990-06-01

This index is a list of American Society of Mechanical Engineers (ASME) Papers that are reprinted in the ASME Transactions series of journals. ASME Papers are often cited only by their paper number, making it difficult to determine if the article has ever appeared in print in the journal literature. This index will be useful for tracking down those papers published as journal articles by the ASME. It will also serve as a guide for retention for subscribers to the ASME Papers and Transaction Series. Paper numbers that appear in the journals may be weeded from the collection of ASME Papers

Interpreting ASME limits and philosophy in FEA of pressure vessel parts

International Nuclear Information System (INIS)

Bezerra, L.M.; Cruz, J.R.B.; Miranda, C.A.J.; Neto, M.M.

1995-01-01

In recent years there has been an effort to interpret finite element (FE) stress results on the light of the ASME B and PV rules and philosophy. Many task groups have issued guidelines on stress linearization and classifications. All those attempts have come up trying to cope modern FE techniques with the rules imposed by the ASME Code. This paper is an independent contribution to the Pressure Vessel Research Council (PVRC) groups which are studying the stress classification and the failure mechanism in a FE framework. This work tries to complement the interesting work by Hollinger and Hechmer presented in the PVP-94 in Minneapolis. In that paper, the authors examined a typical support skirt and showed relations between the skirt collapse load obtained by finite element analysis and the loads allowed from the ASME stress limits. To complement such paper, in the present article, different skirt geometry configurations are analyzed. The configurations here investigated consist of similar support skirts but with different angles of attachments between cylinder and cone parts. It will be possible to observe the influence of the bending stress in the collapse load and its relation to the allowable loads inferred from the ASME limits. A pressure vessel with torispherical head under internal pressure is also examined. Using elastic and limit load FEA, the present paper determines the collapse loads of the configurations. It sets up the relations between these collapse loads, stress categories, and limits dictated by the ASME Code Subsection NB. On the light of NB rules and philosophy, this paper shows how different methods of stress assessment, classification, and limits may influence in the design of a pressure vessel

Thermophysical properties of Na2Th (MoO4)3 (s) and Na4Th (MoO4)4 (s)

International Nuclear Information System (INIS)

Dash, Smruti; Rakshit, S.K.; Singh, Ziley; Keskar, Meera; Dahale, N.D.

2009-01-01

The heat capacity of Na 2 Th (MoO 4 ) 3 (s) and Na 4 Th (MoO 4 ) 4 (s) have been measured by differential scanning calorimeter in the temperature range 318 to 845 K. The corresponding values are: C p,m (Na 2 Th (MoO 4 ) 3 ,s,T) (JK-1 mol-1) 368.710+ 1.0 10-1 (T/K) - 4950267 (K/T)2 (318 ≤ T (K) ≤ 845). C p,m (Na 4 Th (MoO 4 ) 4 ,s,T) (JK-1 mol-1) = 638.761+ 5.12 10-3 (T/K) - 12691691 (K/T)-2 (318 ≤ T (K) ≤ 845). Experimental heat capacity values for Na 2 Th (MoO 4 ) 3 (s) match reasonably well with that of additive oxide values. But C p,m (T) values of Na 4 Th (MoO 4 ) 4 (s) deviates substantially from the additive oxide values above 700 K. The uncertainty of the measurements reported in this study is calculated to be within 1 to 3 % . (author)

8th International Robotic Sailing Conference

CERN Document Server

Haug, Florian

2016-01-01

This book presents the cutting edge developments within a broad field related to robotic sailing. The contributions were presented during the 8th International Robotic Sailing Conference, which has taken place as a part of the 2015 World Robotic Sailing Championships in Mariehamn, Åland (Finland), August 31st – September 4th 2015. Since more than a decade, a series of competitions such as the World Robotic Sailing Championship have stimulated a variety of groups to work on research and development around autonomous sailing robots, which involves boat designers, naval architects, electrical engineers and computer scientists. While many of the challenges in building a truly autonomous sailboat are still unsolved, the books presents the state of the art of research and development within platform optimization, route and stability planning, collision avoidance, power management and boat control.

PREFACE: 7th International Conference on Cooling & Heating Technologies (ICCHT 2014)

Science.gov (United States)

2015-09-01

The Kyoto protocol has initiated a pledge from almost all developing and developed countries to be committed to reducing CO2 emissions. Development of new renewable energy technologies are also of interest in this conference. Greenhouse gases have contributed to global warming and other man-made disasters. Cooling and Heating communities also have responsibilities towards the commitment of reducing the greenhouse gas emissions. In addition, depleting natural resources also act as a threat to the Cooling and Heating industries, causing them to develop highly efficient equipment and innovative technologies. The 1st International Conference on Cooling & Heating Technologies was held in Hanoi Vietnam (Jan. 2005). Whereas the 2nd, 3rd, 4th and 5th ICCHT conferences were held in Dalian, China (Jul. 2006), Tokyo, Japan (Jul. 2007), Jinhae, Korea (Oct. 2008) and Bandung, Indonesia (Dec. 2010) respectively. The 6th International Conference on Cooling & Heating Technologies (ICCTH2012) was held in Xi'an in China on November 9-12, 2012. It is our pleasure to welcome you to the 7th International Conference on Cooling & Heating Technologies (ICCTH2014) on 4th - 6th November 2014 at the Grand Dorsett Subang Hotel, Subang Jaya, Selangor Darul Ehsan, Malaysia The Theme of the Conference is ''Sustainability and Innovation in Heating & Cooling Technologies''. The sub-themes are:- • CO2 Reduction and Low Carbon Technologies • HVAC System and Natural Ventilation • Energy & Alternative Energy • Computational Fluid Dynamics • Low Temperature & Refrigeration Engineering In conjunction with the Conference, an Exhibition will be organized as an integral part of the Conference. Project experiences, product solutions, new applications and state-of-the art information will be highlighted.

Activated sludge model No. 2d, ASM2d

DEFF Research Database (Denmark)

Henze, M.

1999-01-01

The Activated Sludge Model No. 2d (ASM2d) presents a model for biological phosphorus removal with simultaneous nitrification-denitrification in activated sludge systems. ASM2d is based on ASM2 and is expanded to include the denitrifying activity of the phosphorus accumulating organisms (PAOs......). This extension of ASM2 allows for improved modeling of the processes, especially with respect to the dynamics of nitrate and phosphate. (C) 1999 IAWQ Published by Elsevier Science Ltd. All rights reserved....

4th international renewable energy storage conference (IRES 2009)

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-01

Within the 4th International Renewable Energy Storage Conference of The European Association for Renewable Energy (Bonn, Federal Republic of Germany) and The World Council for Renewable Energy (Bonn, Federal Republic of Germany) between 24th and 25 November, 2009, in Berlin (Federal Republic of Germany), the following lectures were held: (1) The World Wind Energy Association (A. Kane); (2) The contribution of wind power to the energy supply of tomorrow (H. Albers); (3) Intelligent energy systems for the integration of renewable energies (A.-C. Agricola); (4) 100% Renewable energies: From fossil baseload plants to renewable plants for basic supply (M. Willenbacher); (5) High-performance Li-ion technology for stationary and mobile applications (A. Gutsch); (6) Energy storage in geological underground - Competition of use at storage formations (L. Dietrich); (7) E-mobility concepts for model region ''Rhein-Ruhr'' in North Rhine Westphalia (G.-U. Funk); (8) Photovoltaic energy storage for a better energy management in residential buildings (S. Pincemin); (9) Self-consuming photovoltaic energy in Germany - Impact on energy flows, business cases, and the distribution grid (M. Braun); (10) Local energy systems -optimized for local consumption of self-produced electricity (B. Wille-Haussmann); (11) Assessing the economics of distributed storage systems at the end consumer level (K.-H. Ahlert); (12) A new transportation system for heat on a wide temperature range (S. Gschwander); (13) Latent heat storage media for cooling applications (C. Doetsch); (14) Numerical and experimental analysis of latent heat storage systems for mobile application (F. Roesler); (15) CO{sub 2}-free heat supply from waste heat (H.-W. Etzkorn); (16) Stationary Li-Ion-technology applications for dispatchable power (C. Kolligs); (17) Redox-flow batteries - Electric storage systems for renewable energy (T. Smolinka); (18) Energy storage by means of flywheels (H. Kielsein); (19

16th International Symposium of Robotic Research

CERN Document Server

Corke, Peter

2016-01-01

This volume presents a collection of papers presented at the 16th International Symposium of Robotic Research (ISRR). ISRR is the biennial meeting of the International Foundation of Robotic Research (IFRR) and its 16th edition took place in Singapore over the period 16th to 19th December 2013. The ISRR is the longest running series of robotics research meetings and dates back to the very earliest days of robotics as a research discipline. This 16th ISRR meeting was held in the 30th anniversary year of the very first meeting which took place in Bretton Woods (New Hampshire, USA) in August 1983., and represents thirty years at the forefront of ideas in robotics research. As for the previous symposia, ISRR 2013 followed up on the successful concept of a mixture of invited contributions and open submissions. 16 of the contributions were invited contributions from outstanding researchers selected by the IFRR officers and the program committee, and the other contributions were chosen among the open submissions afte...

An example of a component replacement when applying ASME N509 and ASME N510 to older ventilation systems

International Nuclear Information System (INIS)

Arndt, T.E.

1994-06-01

This paper presents an example of a component replacement (electric heater) when installed in an older ventilation system that was constructed before the issuance of ASME N509 and N510. Many of the existing ventilation systems at the Hanford Site were designed, fabricated, and installed before the issuance of ASME N509 and N510. Requiring the application of these codes to existing ventilation systems presents challenges to the engineer when design changes are needed. Although it may seem that the application of ASME N509 or N510 may be a hindrance at times, this does not need to occur. Proper preparation at the start of project or design modifications can minimize frustration to the engineer when it is judged that portions of ASME N509 and N510 do not apply in a particular application

Safety Analysis Report for the KRI-ASM Transport Package

Energy Technology Data Exchange (ETDEWEB)

Bang, K. S.; Lee, J. C.; Kim, D. H.; Park, H. Y.; Kim, J. B.; Kim, H. J.; Seo, K. S

2005-11-15

Safety evaluation for the KRI-ASM transport package to transport safely I-131, which is produced at HANARO research reactor in KAERI, was carried out. In the safety analyses results for the KRI-ASM transport package, all the maximum stresses as well as the maximum temperature of the surface are lower than their allowable limits. The safety tests were performed by using the test model of the KRI-ASM transport package. Leak Test was performed after drop test and penetration test, the measured leakage rate was lower than allowable leakage rate. It is revealed that the containment integrity of the KRI-ASM transport package is maintained. Therefore, it shows that the integrity of the KRI-ASM transport package is well maintained.

6th International Microbeam Workshop

Energy Technology Data Exchange (ETDEWEB)

Dr Kevin M. Prise

2004-01-01

The extended abstracts which are submitted here present a summary of the proceedings of the 6th International Workshop/12th LH Gray Workshop: Microbeam Probes of Cellular Radiation Response, held at St. Catherine's College, University of Oxford, UK on March, 29th-31st, 2003. In 1993 the 4th LH Gray Workshop entitled ''Microbeam Probes of Cellular Radiation Response'' was held at the Gray Cancer Institute in Northwood. This was organized by Prof BD Michael, Dr M. Folkard and Dr KM Prise and brought together 40 participants interested in developing and applying new microbeam technology to problems in radiation biology (1). The workshop was an undoubted success and has spawned a series of subsequent workshops every two years. In the past, these workshops have been highly successful in bringing together groups interested in developing and applying micro-irradiation techniques to the study of cell and tissue damage by ionizing radiations. Following the first microbeam workshop, there has been a rapid growth in the number of centres developing radiobiology microbeams, or planning to do so and there are currently 15-20 worldwide. Much of the recent research using microbeams has used them to study low-dose effects and ''non-targeted'' responses such bystander effects, genomic instability and adaptive responses. The goal of the 6th workshop was to build on our knowledge of the development of microbeam approaches and the application to radiation biology in the future with the meeting stretching over a 3 day period. Over 80 participants reviewed the current state of radiobiology microbeam research worldwide and reported on new technological developments both in the fields of physics and biology.

4th International Conference on Condition Monitoring of Machinery in Non-Stationary Operations

CERN Document Server

Zimroz, Radoslaw; Bartelmus, Walter; Haddar, Mohamed

2016-01-01

The book provides readers with a snapshot of recent research and technological trends in the field of condition monitoring of machinery working under a broad range of operating conditions. Each chapter, accepted after a rigorous peer-review process, reports on an original piece of work presented and discussed at the 4th International Conference on Condition Monitoring of Machinery in Non-stationary Operations, CMMNO 2014, held on December 15-16, 2014, in Lyon, France. The contributions have been grouped into three different sections according to the main subfield (signal processing, data mining, or condition monitoring techniques) they are related to. The book includes both theoretical developments as well as a number of industrial case studies, in different areas including, but not limited to: noise and vibration; vibro-acoustic diagnosis; signal processing techniques; diagnostic data analysis; instantaneous speed identification; monitoring and diagnostic systems; and dynamic and fault modeling. This book no...

ASME Code requirements for multi-canister overpack design and fabrication

International Nuclear Information System (INIS)

SMITH, K.E.

1998-01-01

The baseline requirements for the design and fabrication of the MCO include the application of the technical requirements of the ASME Code, Section III, Subsection NB for containment and Section III, Subsection NG for criticality control. ASME Code administrative requirements, which have not historically been applied at the Hanford site and which have not been required by the US Nuclear Regulatory Commission (NRC) for licensed spent fuel casks/canisters, were not invoked for the MCO. As a result of recommendations made from an ASME Code consultant in response to DNFSB staff concerns regarding ASME Code application, the SNF Project will be making the following modifications: issue an ASME Code Design Specification and Design Report, certified by a Registered Professional Engineer; Require the MCO fabricator to hold ASME Section III or Section VIII, Division 2 accreditation; and Use ASME Authorized Inspectors for MCO fabrication. Incorporation of these modifications will ensure that the MCO is designed and fabricated in accordance with the ASME Code. Code Stamping has not been a requirement at the Hanford site, nor for NRC licensed spent fuel casks/canisters, but will be considered if determined to be economically justified

Temporal Deductive Verification of Basic ASM Models

OpenAIRE

Daho, Hocine El-Habib; University of Oran; Benhamamouch, Djillali; University of Oran

2010-01-01

Abstract State Machines (ASMs, for short) provide a practical new computational model which has been applied in the area of software engineering for systems design and analysis. However, reasoning about ASM models occurs, not within a formal deductive system, but basically in the classical informal proofs style of mathematics. Several formal verification approaches for proving correctness of ASM models have been investigated. In this paper we consider the use of the TLA+logic for the deductive...

On the Th internal contamination of animals

International Nuclear Information System (INIS)

Ciubotariu, M.; Danis, A.; Dumitrescu, G.

2000-01-01

Fissionable elements (U,Th) internal contamination have been studied using the fission track method as analysis method of the U and/or Th contaminant elements and Wistar-London breed rats as experiment animals. In our previous studies on the Th internal contamination, we investigated the Th biodistribution and retention in all the vital organs of the contaminated rats. In this stage, we continued this study with the Th elimination investigation through urine and excrements. The identical aliquot parts of a solution calibrated in Th, corresponding to an Annual Limit Intake, three Wistar-London breed rats were contaminated. They were kept in normal life conditions and under permanent medical surveillance up to their sacrifice. The animals were sacrificed at different time intervals after their contamination: RAT 1 = 2 days, RAT 2 = 7 days and RAT 3 = 14 days, respectively. After the sacrifice, their vital organs were sampled, weighed, calcined, re-weighed and finally analysed by track detection using the fission track micro-mappings technique. The evacuations were sampled every 24 hours: urine, on the filter paper, and all excrements balls. The samples were weighed before and after calcination and analysed in the same way as the vital organs. The Th fission track micro-mappings technique was used in the following conditions: - mica-muscovite as track detector pre-etched for fossil tracks 18 h in HF-40 per cent at room temperature; - the neutron irradiations were performed in the nuclear reactor WWR-S Bucharest at the neutron fluences of 3·10 15 - 2·10 16 fast neutrons/cm 2 ; - the visualization of the Th induced fission tracks was obtained by chemical etching in HF-40 %, 3 h at room temperature; - the Th track micromappings obtained in track detectors were studied by optical microscopy using a stereo microscope WILD M7S for ensemble study (X6-X31) and a binocular Zeiss JENA microscope for qualitative and quantitative studies (X150). The investigation of the Th

8th International Workshop on Simulation

CERN Document Server

Rasch, Dieter; Melas, Viatcheslav; Moder, Karl; Statistics and simulation

2018-01-01

This volume features original contributions and invited review articles on mathematical statistics, statistical simulation and experimental design. The selected peer-reviewed contributions originate from the 8th International Workshop on Simulation held in Vienna in 2015. The book is intended for mathematical statisticians, Ph.D. students and statisticians working in medicine, engineering, pharmacy, psychology, agriculture and other related fields. The International Workshops on Simulation are devoted to statistical techniques in stochastic simulation, data collection, design of scientific experiments and studies representing broad areas of interest. The first 6 workshops took place in St. Petersburg, Russia, in 1994 – 2009 and the 7th workshop was held in Rimini, Italy, in 2013.

Smart energy systems and 4th generation district heating

DEFF Research Database (Denmark)

Lund, Henrik; Duic, Neven; Østergaard, Poul Alberg

2016-01-01

scientific understanding on how we can design and implement a suitable and least-cost transformation into a sustainable energy future. The concept of Smart Energy Systems emphasizes the importance of being coherent and cross-sectoral when the best solutions are to be found and how this also calls......This editorial gives an introduction to the important relationship between Smart Energy Systems and 4th Generation District Heating and presents a number of selected papers from the 1st International Conference on the topic. All of the papers elaborate on or otherwise contribute to the theoretical...... for the active inclusion of the heating and cooling sectors. The concept of 4th Generation District Heating emphasizes that district heating and cooling are both important elements but also technologies that have to be developed further into a 4th generation version to be able to fulfil their roles in future...

4th IEEE/ACIS International Conference on Computer and Information Science

CERN Document Server

2016-01-01

This edited book presents scientific results of the 14th IEEE/ACIS International Conference on Computer and Information Science (ICIS 2015) which was held on June 28 – July 1, 2015 in Las Vegas, USA. The aim of this conference was to bring together researchers and scientists, businessmen and entrepreneurs, teachers, engineers, computer users, and students to discuss the numerous fields of computer science and to share their experiences and exchange new ideas and information in a meaningful way. Research results about all aspects (theory, applications and tools) of computer and information science, and to discuss the practical challenges encountered along the way and the solutions adopted to solve them.

An example of a component replacement when applying ASME N509 and ASME N510 to older ventilation systems

Energy Technology Data Exchange (ETDEWEB)

Arndt, T.E. [Westinghouse Hanford Company, Richland, WA (United States)

1995-02-01

This paper presents an example of a component replacement (electric heater) when installed in an older ventilation system that was constructed before the issuance of ASME N509{sup 1} and N510{sup 2}. Many of the existing ventilation systems at the Hanford Site were designed, fabricated, and installed before the issuance of ASME N509{sup 1} and N510{sup 2}. Requiring the application of these codes to existing ventilation systems presents challenges to the engineer when design changes are needed. Although it may seem that the application of ASME N509{sup 1} or N510{sup 2} may be a hindrance at times, this does not need to occur. Proper preparation at the start of project or design modifications can minimize frustration to the engineer when it is judged that portions of ASME N509{sup 1} and N510{sup 2} do not apply in a particular application.

Structure and luminescence of α and β ThBr4: optical properties of U4+ in α ThBr4

International Nuclear Information System (INIS)

Simoni, E.

1988-05-01

The aim of this work is to understand the comparative structural and intrinsic luminescence properties of the pure matrices α and β - ThBr 4 , and to study the electronic structure by optical spectroscopy of the U 4+ ion in the α-ThBr 4 matrix. 1)Under U.V. excitation, βThBr 4 is intensively fluorescent in the blue-purple and α-ThBr 4 is fluorescent in the red. The main results concerning β-ThBr 4 are the following: -the optical absorption in the U.V. is under the form of a sudden absorption front and for a same temperature, its threshold energy has the same value as the threshold energy of the excitation function and of the photocurrent peak; -the intensity and the life time of the emission decrease when the temperature increases from 300 K until 400 K ( extinction temperature). All the obtained results have been explained either with the molecular orbitals levels of the ThBr 8 4- cluster or with the valence and conduction bands of the pure matrix. 2)The absorption and emission spectra of U 4+ in α-ThBr 4 (in which U 4+ has a point symmetry S 4 ) obtained between 300 K and 4.2 K have allowed to index 30 levels. The calculation of the spectroscopic parameters F k , ξ and B k q has been carried out in symmetry D 2d and S 4 . The comparison of these parameters with those calculated for U 4+ in β-ThBr 4 and β-ThCl 4 show that the global force of the crystalline field is practically the same in the three matrices, but that the structure transformation β→α occurs more on the values of these B k q than on the change of the ligands Br - →Cl - . On the other hand, it has been possible with the α-ThBr 4 matrix, or the β-ThBr 4 and the β-ThCl 4 , to observe the fluorescence spectra of the U 4+ ion (particularly weak phonons energies). (O.M.)

9th International conference on CANDU maintenance

International Nuclear Information System (INIS)

2011-01-01

The 9th International Conference on CANDU Maintenance was held in Toronto, Ontario, Canada on December 4-6, 2011. The conference focused on Nuclear plant reliability and maintenance. Equipment reliability is a critical factor in achieving safe and reliable Nuclear Power Plant operations for many reasons. For one it reduces the challenges upon the operating staff and allows station personnel to 'go on the offence' instead of having to play defense in a reactive mode. Plant reliability ensures that there is time to study the issues in detail and develop solutions for long-term success. Let us not forget that the owner carries the burden of demonstrating the return on investment, and plant reliability goes a long way in helping to make the case for plant life extension. A good reputation for plant reliability provides the public capital necessary to build confidence and facilitate the licensing process. The proceedings papers and presentations given at the 9th International Conference on Candu Maintenance covered topics that include: Managing Worker; Radiation Dose; Full Life Cycle Management; Managing Maintenance Refurbishment; Designing for Maintainability; Inspection Techniques; and, Mitigating Degradation.

Review of ASME-NH Design Materials for Creep-Fatigue

International Nuclear Information System (INIS)

Koo, Gyeong Hoi; Kim, Jong Bum

2010-01-01

To review and recommend the candidate design materials for the Sodium-Cooled Fast Reactor, the material sensitivity evaluations by the comparison of design data between the ASME-NH materials were performed by using the SIE ASME-NH computer program implementing the material database of the ASME-NH. The design material data provided by the ASME-NH code are the elastic modulus and yield Strength, Time-Independent Allowable Stress Intensity value, time-dependent allowable stress intensity value, expected minimum stress-to rupture value, stress rupture Factors for weldment, isochronous stress-strain curves, and design fatigue curves. Among these, the data related with the creep-fatigue evaluation are investigated in this study

Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1.

Science.gov (United States)

Quante, Timo; Ng, Yee Ching; Ramsay, Emma E; Henness, Sheridan; Allen, Jodi C; Parmentier, Johannes; Ge, Qi; Ammit, Alaina J

2008-08-01

The mechanisms by which corticosteroids reduce airway inflammation are not completely understood. Traditionally, corticosteroids were thought to inhibit cytokines exclusively at the transcriptional level. Our recent evidence, obtained in airway smooth muscle (ASM), no longer supports this view. We have found that corticosteroids do not act at the transcriptional level to reduce TNF-alpha-induced IL-6 gene expression. Rather, corticosteroids inhibit TNF-alpha-induced IL-6 secretion by reducing the stability of the IL-6 mRNA transcript. TNF-alpha-induced IL-6 mRNA decays at a significantly faster rate in ASM cells pretreated with the corticosteroid dexamethasone (t(1/2) = 2.4 h), compared to vehicle (t(1/2) = 9.0 h; P ASM cells.

Highlights of the 8th International Veterinary Immunology Symposium

Science.gov (United States)

Veterinary immunologists have expanded understanding of the immune systems for our companion animals and developed new vaccines and therapeutics. This manuscript summarizes the highlights of the 8th International Veterinary Immunology Symposium (8 th IVIS) held August 15th-19th, 2007, in Ouro Preto,...

[History of the 4th Department of Internal Medicine of the First Faculty of Medicine at Charles University and the General University Hospital in Prague].

Science.gov (United States)

Bartůněk, Petr

In 2015, the doctors and nurses of the 4th Department of Internal Medicine of the First Faculty of Medicine, Charles University and the General University Hospital in Prague celebrated the 70th anniversary of its founding. The article summarizes the clinics contribution to the field of internal medicine, and particularly to angiology, hepatogastroenterology and lipidology. It comments the clinics current activities and the possibilities of its further development. Attention is also paid to the tradition of high ethical and professional standards of medical care in accordance with the norms established by the clinic's founder, prof. MUDr. Bohumil Prusík.

Comparative study of α and β-ThBr4: structure and luminescence. Spectroscopy of U4+ in α-ThBr4

International Nuclear Information System (INIS)

Simoni, E.

1988-05-01

UV absorption of β-ThBr 4 : presents a plain absorption front and for the same temperature the threshold energy has the same value than the threshold energy of excitation function and photocurrent peak. Emission intensity and lifetime decrease when temperature increases from 300 K to 400K (extinction temperature). Results are interpreted either by molecular orbital levels of the ThBr 8 4- cluster or either by conduction and valence bands of the matrix above. Absorption and emission spectra of U 4+ in α-ThBr 4 (where U 4+ has a S 4 symmetry) between 300 K and 4.2 K allow indexation of 30 levels. Spectroscopic parameters are calculated in D 2d and S 4 symmetry. Comparison of these parameters with those of U 4+ in β-ThBr 4 and β-ThCl 4 shows that crystal field force is practically the same in the three matrices but the structure transformation from β to α has more influence on B q k than ligand change from Br - to Cl - . Owing to very low phonon energy, fluorescence spectra of U 4+ is easy to observe in α-ThBr 4 as it is in β-ThBr 4 and ThCl 4 [fr

4th International Language Management Symposium

Czech Academy of Sciences Publication Activity Database

Prošek, Martin

2016-01-01

Roč. 77, č. 3 (2016), s. 233-240 ISSN 0037-7031. [international language management symposium] Institutional support: RVO:68378092 Keywords : language management theory * international language symposium * language management Subject RIV: AI - Linguistics OBOR OECD: Linguistics Impact factor: 0.625, year: 2016

Cisco ASM Router

CERN Multimedia

2001-01-01

One of the two "ASM/2-32EM" boxes installed in 1988, from "Cisco Systems Inc." - then an unknown 20-employee company in Menlo Park, California (USA). This is one of the first two Cisco boxes to appear in Switzerland, and possibly Europe. The 220v power supply was a special modification made for use at CERN. They supported IP address filtering, which seemed just what CERN needed to help protect the new Cray XMP-48 super computer from network hackers. The two ASM boxes were both routers and terminal servers. They protected a secure private Ethernet segment used by the Cray project, as well as providing secure terminal connections to that segment, including CERN's first dialback terminal service, which allowed Cray and CERN system analysts to work on the machine from home, using another Cisco feature called TACACS. (Kindly offered by B. Segal who discovered this company while at a Usenix Conference in Phoenix, Arizona in June 1987.)

Report on the Current Technical Issues on ASME Nuclear Code and Standard

International Nuclear Information System (INIS)

Koo, Gyeong Hoi; Lee, B. S.; Yoo, S. H.

2008-11-01

This report describes the analysis on the current revision movement related to the mechanical design issues of the U.S ASME nuclear code and standard. ASME nuclear mechanical design in this report is composed of the nuclear material, primary system, secondary system and high temperature reactor. This report includes the countermeasures based on the ASME Code meeting for current issues of each major field. KAMC(ASME Mirror Committee) of this project is willing to reflect a standpoint of the domestic nuclear industry on ASME nuclear mechanical design and play a technical bridge role for the domestic nuclear industry in ASME Codes application

30th International Acoustical Imaging Symposium

CERN Document Server

Jones, Joie; Lee, Hua

2011-01-01

The International Symposium on Acoustical Imaging is a unique forum for advanced research, covering new technologies, developments, methods and theories in all areas of acoustics. This interdisciplinary Symposium has been taking place every two years since 1968. In the course of the years the proceedings volumes in the Acoustical Imaging Series have become a reference for cutting-edge research in the field. In 2009 the 30th International Symposium on Acoustical Imaging was held in Monterey, CA, USA, March 1-4. Offering both a broad perspective on the state-of-the-art as well as  in-depth research contributions by the specialists in the field, this Volume 30 in the Series contains an excellent collection of forty three papers presented in five major categories: Biomedical Imaging Acoustic Microscopy Non-Destructive Evaluation Systems Analysis Signal Analysis and Image Processing Audience Researchers in medical imaging and biomedical instrumentation experts.

Regulation of dynein-mediated autophagosomes trafficking by ASM in CASMCs.

Science.gov (United States)

Xu, Ming; Zhang, Qiufang; Li, Pin-Lan; Nguyen, Thaison; Li, Xiang; Zhang, Yang

2016-01-01

Acid sphingomyelinase (ASM; gene symbol Smpd1) has been shown to play a crucial role in autophagy maturation by controlling lysosomal fusion with autophagosomes in coronary arterial smooth muscle cells (CASMCs). However, the underlying molecular mechanism by which ASM controls autophagolysosomal fusion remains unknown. In primary cultured CASMCs, lysosomal Ca2+ induced by 7-ketocholesterol (7-Ket, an atherogenic stimulus and autophagy inducer) was markedly attenuated by ASM deficiency or TRPML1 gene silencing suggesting that ASM signaling is required for TRPML1 channel activity and subsequent lysosomal Ca(2+) release. In these CASMCs, ASM deficiency or TRPML1 gene silencing markedly inhibited 7-Ket-induced dynein activation. In addition, 7-Ket-induced autophagosome trafficking, an event associated with lysosomal Ca(2+) release and dynein activity, was significantly inhibited in ASM-deficient (Smpd1(-/-)) CASMCs compared to that in Smpd1(+/+) CASMCs. Finally, overexpression of TRPML1 proteins restored 7-Ket-induced lysosomal Ca(2+) release and autophagosome trafficking in Smpd1-/- CASMCs. Collectively, these results suggest that ASM plays a critical role in regulating lysosomal TRPML1-Ca(2+) signaling and subsequent dynein-mediated autophagosome trafficking, which leads its role in controlling autophagy maturation in CASMCs under atherogenic stimulation.

ASME nuclear codes and standards risk management strategic planning

International Nuclear Information System (INIS)

Hill, Ralph S. III; Balkey, Kenneth R.; Erler, Bryan A.; Wesley Rowley, C.

2007-01-01

This paper is prepared in honor and in memory of the late Professor Emeritus Yasuhide Asada to recognize his contributions to ASME Nuclear Codes and Standards initiatives, particularly those related to risk-informed technology and System Based Code developments. For nearly two decades, numerous risk-informed initiatives have been completed or are under development within the ASME Nuclear Codes and Standards organization. In order to properly manage the numerous initiatives currently underway or planned for the future, the ASME Board on Nuclear Codes and Standards (BNCS) has an established Risk Management Strategic Plan (Plan) that is maintained and updated by the ASME BNCS Risk Management Task Group. This paper presents the latest approved version of the plan beginning with a background of applications completed to date, including the recent probabilistic risk assessment (PRA) standards developments for nuclear power plant applications. The paper discusses planned applications within ASME Nuclear Codes and Standards that will require expansion of the ASME PRA Standard to support new advanced light water reactor and next generation reactor developments, such as for high temperature gas-cooled reactors. Emerging regulatory developments related to risk-informed, performance- based approaches are summarized. A long-term vision for the potential development and evolution to a nuclear systems code that adopts a risk-informed approach across a facility life-cycle (design, construction, operation, maintenance, and closure) is also summarized. Finally, near term and long term actions are defined across the ASME Nuclear Codes and Standards organizations related to risk management, including related U.S. regulatory activities. (author)

4th Pacific Rim Underwater Acoustics Conference

CERN Document Server

Xu, Wen; Cheng, Qianliu; Zhao, Hangfang

2016-01-01

These proceedings are a collection of 16 selected scientific papers and reviews by distinguished international experts that were presented at the 4th Pacific Rim Underwater Acoustics Conference (PRUAC), held in Hangzhou, China in October 2013. The topics discussed at the conference include internal wave observation and prediction; environmental uncertainty and coupling to sound propagation; environmental noise and ocean dynamics; dynamic modeling in acoustic fields; acoustic tomography and ocean parameter estimation; time reversal and matched field processing; underwater acoustic localization and communication as well as measurement instrumentations and platforms. These proceedings provide insights into the latest developments in underwater acoustics, promoting the exchange of ideas for the benefit of future research.

Assessment of induction elbows for an ASME Code application

International Nuclear Information System (INIS)

Panesar, J.S.; Soliman, M.

1991-01-01

The ASME Nuclear Codes impose some specific requirements on the wall thickness uniformity and the out-of-roundness of cross sections of the elbows for Nuclear Power Plant applications. Due to some of these requirements, manufacturing and installation of these elbows can be time consuming and quite expensive. This paper explores the feasibility of using induction elbows for nuclear application from the stress analysis point of view. To this end, three different sizes of 90deg elbows have been analyzed based on the geometry of an 'ASME Code' elbow and an elbow formed by induction bending. The analysis is carried out for internal pressure, in-plane and out-of-plane loads. Based on the results of these three carbon steel elbows, the use of induction elbows in some of the CANDU-PHW (CANadian Deuterium Uranium-Pressurized Heavy Water) power plant applications seems encouraging. However, before the feasibility can be fully confirmed analysis and induction bending tests over a wider range of geometries, loading conditions, and materials are required. (author)

Proceedings of the 20th International Conference on Ion Beam Modification of Materials (IBMM 2016)

Science.gov (United States)

Kennedy, John; Elliman, Robert; Mccallum, Jeffrey; Ionescu, Mihail; Markwitz, Andreas

2017-10-01

The papers in this issue of NIMB were presented at the 20th international conference on Ion Beam Modification of Materials (IBMM) held at Te Papa Museum, Wellington, New Zealand from October 30th until November 4th, 2016. This conference continued the proud legacy of New Zealand-born Lord Rutherford and his pioneering research in ion beam physics.

MAGLEV `95. 14th international conference on magnetically levitated systems. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

The proceedings present the papers of the 14th International Conference on Magnetically Levitated Systems held in Bremen, FRG, in November 1995. For 70 of 74 papers a separate subject analysis has been carried out. 4 papers are not available in the proceedings. (HW)

Challenge - converting to ANSI/ASME NQA Standard 1

International Nuclear Information System (INIS)

Nansen, J.N.

1983-03-01

Prior to August, 1980, Westinghouse Hanford Company operated the Hanford Engineering Development Laboratory Quality Program in accordance with the requirements of RDT F 2-2T and RDT F 2-4T and for a short while to ANSI N45.2. Following the issuance of the national consensus standard ANSI/ ASME NQA Standard 1 in August 1979, and its acceptance by DOE, the Laboratory began making changes to meet these requirements in its internal quality program in August 1980. This was followed with the invoking of these requirements on supplier's programs and all procurement activities in March of 1981. This conversion was completed in approximately six months and provided an opportunity for several improvements. The keynote of this standard is flexibility. A major improvement noted was in the flexibility of application. The program can be tailored to meet specific needs. Vendor surveys under NQA-1 have shown positive results in that the organization and structure of the standard is much easier to follow and understand

AsmL Specification of a Ptolemy II Scheduler

DEFF Research Database (Denmark)

Lázaro Cuadrado, Daniel; Koch, Peter; Ravn, Anders Peter

2003-01-01

Ptolemy II is a tool that combines different computational models for simulation and design of embedded systems. AsmL is a software specification language based on the Abstract State Machine formalism. This paper reports on development of an AsmL model of the Synchronous Dataflow domain scheduler...

17th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2012-01-01

Cryocoolers 17 archives developments and performance measurements in the field of cryocoolers based on the contributions of leading international experts at the 17th International Cryocooler Conference that was held in Los Angeles, California, on July 9-12, 2012. The program of this conference consisted of 94 papers; of these, 71 are published here. Over the years the International Cryocoolers Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

16th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2011-01-01

Cryocoolers 16 archives developments and performance measurements in the field of cryocoolers based on the contributions of leading international experts at the 16th International Cryocooler Conference that was held in Atlanta, Georgia, on May 17-20, 2010. The program of this conference consisted of 116 papers; of these, 89 are published here. Over the years the International Cryocoolers Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

Comparison of SKIFS 2004:1 and Tillsynshandbok PSA against the ASME PRA Standard and European requirements on PSA

International Nuclear Information System (INIS)

Hellstroem, Per

2005-04-01

Requirements on PSA for risk informed applications are expressed in different international documents. The ASME PRA standard published in spring 2002 is one such document, PSA requirements are also expressed in the European Utility Requirements (EUR) for new reactors. The Swedish PSA requirements are provided in the Swedish regulators (SKI) statutes SKIFS 2004:1. SKI also has a review handbook for PSA activities (SKI report 2003:48). The review handbook is a support during review of the utilities PSA activities and the PSAs themselves. The review handbook expresses SKIs expectations by providing so called important aspects for both the PSA work and the PSAs, A comparison of SKIFS requirements and the important aspects in the Review handbook, on one side, and the requirements on PSA in EUR and ASME on the other side, is presented. The comparison shows a large difference in the level of detail in the different documents, where ASME is most detailed and specific. This is expected since the SKI review handbook not is a 'PSA guide' in the same way as the ASME PRA standard. A direct comparison of the ASME PRA standard requirements with the important aspects in the review handbook cannot answer the question which ASME capacity level that is achieved by a PSA meeting all important aspects. The conclusion is that it is not likely to achieve capacity level 2 and 3, since very few ASME level 3 attributes are explicitly expressed as important aspects, though many are expressed in general terms. The review handbook important aspects that are most similar to the ASME capacity level 1 attributes are initiating events, sequence analysis, and system analysis while less similarity is found for analysis of operator actions data analysis, quantification and containment analysis (level 2). Less similarity is found for capacity level 2 and 3. However, the number of additional ASME attributes on capacity level 2 and 3 are few. There are also important aspects in the review handbook that

A simple access to pure thorium(IV) halides (ThCl{sub 4}, ThBr{sub 4}, and ThI{sub 4})

Energy Technology Data Exchange (ETDEWEB)

Deubner, H. Lars; Rudel, Stefan Sebastian; Kraus, Florian [Fachbereich Chemie, Philipps-Universitaet Marburg (Germany)

2017-12-13

In this work we present a facile, lab scale synthesis for thorium tetrahalides ThX{sub 4} (X = Cl, Br, and I). The reaction between the easily available ThO{sub 2} and AlX{sub 3} (X = Cl, Br, and I) and a subsequent in situ chemical vapor transport (CVT) leads to a product of high purity, which is obtained in the form of crystals or large aggregates of crystals. Their identity and purity was evidenced by X-ray powder diffraction and IR spectroscopy. The usage of ThO{sub 2} avoids, unlike earlier syntheses, the utilization of scarcely available thorium metal or of other reactants, such as CCl{sub 4}, which leads to impurities. Furthermore, the reaction tolerates even less pure ThO{sub 2}. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

A user's perspective on the merits and shortcomings of ASME Section III

International Nuclear Information System (INIS)

Antaki, G.A.

1994-01-01

There are several aspects of Section III which when compared to process industry codes (ASME VIII, ASME B31.3, API, etc.) have proven to be a significant improvement in engineering practice. There are, however, other aspects of ASME III which have added to costs without clear benefits in safety or reliability. The authors present a user's perspective on some of the relative merits and shortcomings of the nuclear codes (ASME III and XI) compared to the process industry codes (such as ASME VIII, B31.3 and API)

Significant issues and changes for ANSI/ASME OM-1 1981, part 1, ASME OMc code-1994, and ASME OM Code-1995, Appendix I, inservice testing of pressure relief devices in light water reactor power plants

Energy Technology Data Exchange (ETDEWEB)

Seniuk, P.J.

1996-12-01

This paper identifies significant changes to the ANSI/ASME OM-1 1981, Part 1, and ASME Omc Code-1994 and ASME OM Code-1995, Appendix I, {open_quotes}Inservice Testing of Pressure Relief Devices in Light-Water Reactor Power Plants{close_quotes}. The paper describes changes to different Code editions and presents insights into the direction of the code committee and selected topics to be considered by the ASME O&M Working Group on pressure relief devices. These topics include scope issues, thermal relief valve issues, as-found and as-left set-pressure determinations, exclusions from testing, and cold setpoint bench testing. The purpose of this paper is to describe some significant issues being addressed by the O&M Working Group on Pressure Relief Devices (OM-1). The writer is currently the chair of OM-1 and the statements expressed herein represents his personal opinion.

Significant issues and changes for ANSI/ASME OM-1 1981, part 1, ASME OMc code-1994, and ASME OM Code-1995, Appendix I, inservice testing of pressure relief devices in light water reactor power plants

International Nuclear Information System (INIS)

Seniuk, P.J.

1996-01-01

This paper identifies significant changes to the ANSI/ASME OM-1 1981, Part 1, and ASME Omc Code-1994 and ASME OM Code-1995, Appendix I, open-quotes Inservice Testing of Pressure Relief Devices in Light-Water Reactor Power Plantsclose quotes. The paper describes changes to different Code editions and presents insights into the direction of the code committee and selected topics to be considered by the ASME O ampersand M Working Group on pressure relief devices. These topics include scope issues, thermal relief valve issues, as-found and as-left set-pressure determinations, exclusions from testing, and cold setpoint bench testing. The purpose of this paper is to describe some significant issues being addressed by the O ampersand M Working Group on Pressure Relief Devices (OM-1). The writer is currently the chair of OM-1 and the statements expressed herein represents his personal opinion

4th International Conference on Computational Collective Intel- ligence Technologies and Applications (ICCCI 2012)

CERN Document Server

Trawiński, Bogdan; Katarzyniak, Radosław; Jo, Geun-Sik; Advanced Methods for Computational Collective Intelligence

2013-01-01

The book consists of 35 extended chapters which have been selected and invited from the submissions to the 4th International Conference on Computational Collective Intelligence Technologies and Applications (ICCCI 2012) held on November 28-30, 2012 in Ho Chi Minh City, Vietnam. The book is organized into six parts, which are semantic web and ontologies, social networks and e-learning, agent and multiagent systems, data mining methods and applications, soft computing, and optimization and control, respectively. All chapters in the book discuss theoretical and practical issues connected with computational collective intelligence and related technologies. The editors hope that the book can be useful for graduate and Ph.D. students in Computer Science, in particular participants in courses on Soft Computing, Multiagent Systems, and Data Mining. This book can be also useful for researchers working on the concept of computational collective intelligence in artificial populations. It is the hope of the editors that ...

Preferential susceptibility of Th9 and Th2 CD4+ T cells to X4-tropic HIV-1 infection.

Science.gov (United States)

Orlova-Fink, Nina; Chowdhury, Fatema Z; Sun, Xiaoming; Harrington, Sean; Rosenberg, Eric S; Yu, Xu G; Lichterfeld, Mathias

2017-10-23

The functional polarization of CD4 T cells determines their antimicrobial effector profile, but may also impact the susceptibility to infection with HIV-1. Here, we analyzed the susceptibility of CD4 T cells with different functional polarization to infection with X4 and R5-tropic HIV-1. CD4 T cells with a Th1, Th2, Th17, and Th9 polarization were subjected to in-vitro infection assays with X4, R5, or vesicular stomatitis virus-G protein-pseudotyped HIV-1. In addition, we sorted differentially polarized CD4 T-cell subsets from individuals treated with antiretroviral therapy and analyzed the tropism of viral env sequences. Th9-polarized CD4 T cells and, to a lesser extent, Th2-polarized CD4 T cells expressed higher surface levels of CXCR4, and are more permissive to X4-tropic infection in vitro. In contrast, Th1 and Th17 CD4 T cells exhibited stronger surface expression of CCR5, and were more susceptible to infection with R5-tropic viruses. Correspondingly, the distribution of X4-tropic viral sequences in antiretroviral therapy-treated HIV-1-infected patients was biased toward Th9/Th2 cells, whereas R5-tropic sequences were more frequently observed in Th17 cells. CD4 T-cell polarization is associated with a distinct susceptibility to X4 and R5-tropic HIV-1 infection.

9th International Conference on Boundary Elements

CERN Document Server

Wendland, W; Kuhn, G

1987-01-01

This book contains the edited versions of most of the papers presented at the 9th International Conference on Boundary Elements held at the University of Stuttgart, Germany from August 31st to September 4th, 1987, which was organized in co-operation with the Computational Mechanics Institute and GAMM (Society for Applied Mathematics and Mechanics). This Conference, as the previous ones, aimed to review the latest developments in technique and theory and point out new advanced future trends. The emphasis of the meeting was on the engineering advances versus mathematical formulations, in an effort to consolidate the basis of many new applications. Recently engineers have proposed different techniques to solve non-linear and time dependent problems and many of these formulations needed a better mathematical understanding. Furthermore, new approximate formulations have been proposed for boundary elements which appeared to work in engineering practice, but did not have a proper theoretical background. The Conferen...

18th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2014-01-01

Cryocoolers 18 Cryocoolers 18 archives developments and performance measurements in the field of cryocoolers based on the contributions of leading international experts at the 18th International Cryocooler Conference that was held in Syracuse, New York, on June 9-12, 2014. The program of this conference lead to the 76 peer-reviewed papers that are published here. Over the years the International Cryocoolers Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

ASME nuclear codes and standards risk management strategic plan

International Nuclear Information System (INIS)

Balkey, Kenneth R.

2003-01-01

Over the past 15 years, several risk-informed initiatives have been completed or are under development within the ASME Nuclear Codes and Standards organization. In order to better manage the numerous initiatives in the future, the ASME Board on Nuclear Codes and Standards has recently developed and approved a Risk Management Strategic Plan. This paper presents the latest approved version of the plan beginning with a background of applications completed to date, including the recent issuance of the ASME Standard for Probabilistic Risk Assessment (PRA) for Nuclear Power Plant Applications. The paper discusses potential applications within ASME Nuclear Codes and Standards that may require expansion of the PRA Standard, such as for new generation reactors, or the development of new PRA Standards. A long-term vision for the potential development and evolution to a nuclear systems code that adopts a risk-informed approach across a facility life-cycle (design, construction, operation, maintenance, and closure) is summarized. Finally, near term and long term actions are defined across the ASME Nuclear Codes and Standards organizations related to risk management, and related U.S. regulatory activities are also summarized. (author)

Computer Program of SIE ASME-NH (Revision 1.0) Code

Energy Technology Data Exchange (ETDEWEB)

Koo, Gyeong Hoi; Lee, J. H

2008-01-15

In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail.

Computer Program of SIE ASME-NH (Revision 1.0) Code

International Nuclear Information System (INIS)

Koo, Gyeong Hoi; Lee, J. H.

2008-01-01

In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail

Recent development in the ASME O and M committee codes, standards, and guides

International Nuclear Information System (INIS)

Rowley, C.W.

1999-01-01

The ASME O and M Committee continues to expand and update its code, standards, and guides as contained in the ASME OM Code and the ASME OM Standards/Guides. This paper will describe recent changes to these two ASME documents, including technical inquiries, code cases, and the major reformat of the ASME OM Code 1998 Edition. Also two new Parts to the ASME OM S/G will be discussed: OM Part 23 and OM Part 24, which are close to being initially published. A third new Part to the ASME OM S/G has been authorized and has recently started to get organized: Part 26, 'Thermal Calibration of RTDs'. In addition this paper will describe the future plans for these two documents as provided in the O and M Committee Strategic Plan. (author)

The 4th international comparison on EPR dosimetry with tooth enamel

Energy Technology Data Exchange (ETDEWEB)

Fattibene, P., E-mail: paola.fattibene@iss.it [Istituto Superiore di Sanita, Department of Technology and Health, Viale Regina Elena 299, I-00162 Rome (Italy); Wieser, A. [Helmholtz Zentrum Muenchen, Neuherberg D-85764 (Germany); Adolfsson, E. [Linkoeping University, SE-58185 Linkoeping (Sweden); Benevides, L.A. [Naval Dosimetry Center, Bethesda MD 20889-5600 (United States); Brai, M. [University of Palermo, I-90128 Palermo (Italy); Callens, F. [Ghent University, B-9000 Gent (Belgium); Chumak, V. [Research Center for Radiation Medicine AMS, 04050 Kiev (Ukraine); Ciesielski, B. [Medical University of Gdansk, 80-211 Gdansk (Poland); Della Monaca, S. [Istituto Superiore di Sanita, Department of Technology and Health, Viale Regina Elena 299, I-00162 Rome (Italy); Regina Elena Institute, I-00144 Rome (Italy); Emerich, K. [Medical University of Gdansk, 80-211 Gdansk (Poland); Department of Paediatric Dentistry, 80-208 Gdansk (Poland); Gustafsson, H. [Linkoeping University, SE-58185 Linkoeping (Sweden); Hirai, Y. [Radiation Effects Research Foundation, Minami-ku, Hiroshima 732-0815 (Japan); Hoshi, M. [Hiroshima University, Minami-ku, Hiroshima 734-8553 (Japan); Israelsson, A. [Linkoeping University, SE-58185 Linkoeping (Sweden); Ivannikov, A. [Medical Radiological Research Center, Obninsk, Kaluga region (Russian Federation); Ivanov, D. [Institute of Metal Physics, Yekaterinburg 620041 (Russian Federation); Kaminska, J. [Medical University of Gdansk, 80-211 Gdansk (Poland); Ke, Wu [Beijing Institute of Radiation Medicine, Beijing 100850 (China); Lund, E. [Linkoeping University, SE-58185 Linkoeping (Sweden); Marrale, M. [University of Palermo, I-90128 Palermo (Italy)

2011-09-15

This paper presents the results of the 4th International Comparison of in vitro electron paramagnetic resonance dosimetry with tooth enamel, where the performance parameters of tooth enamel dosimetry methods were compared among sixteen laboratories from all over the world. The participating laboratories were asked to determine a calibration curve with a set of tooth enamel powder samples provided by the organizers. Nine molar teeth extracted following medical indication from German donors and collected between 1997 and 2007 were prepared and irradiated at the Helmholtz Zentrum Muenchen. Five out of six samples were irradiated at 0.1, 0.2, 0.5, 1.0 and 1.5 Gy air kerma; and one unirradiated sample was kept as control. The doses delivered to the individual samples were unknown to the participants, who were asked to measure each sample nine times, and to report the EPR signal response, the mass of aliquots measured, and the parameters of EPR signal acquisition and signal evaluation. Critical dose and detection limit were calculated by the organizers on the basis of the calibration-curve parameters obtained at every laboratory. For calibration curves obtained by measuring every calibration sample three times, the mean value of the detection limit was 205 mGy, ranging from 56 to 649 mGy. The participants were also invited to provide the signal response and the nominal dose of their current dose calibration curve (wherever available), the critical dose and detection limit of which were also calculated by the organizers.

Future direction of ASME nuclear codes and standards

International Nuclear Information System (INIS)

Ennis, Kevin; Sheehan, Mark E.

2003-01-01

While the nuclear power industry in the US is in a period of stasis, there continues to be a great deal of activity in the ASME nuclear standards development arena. As plants age, the need for new approaches in standardization changes with the changing needs of the industry. New tools are becoming available in the form of risk analysis, and this is finding its way into more and more of ASME's standards activities. This paper will take a look at the direction that ASME nuclear Codes and Standards are heading in this and other areas, as well as taking a look at some advance reactor concepts and plans for standards to address new technologies

IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation.

Science.gov (United States)

Mitchell, Ruth E; Hassan, Masriana; Burton, Bronwen R; Britton, Graham; Hill, Elaine V; Verhagen, Johan; Wraith, David C

2017-09-12

IL-10 is an immunomodulatory cytokine with a critical role in limiting inflammation in immune-mediated pathologies. The mechanisms leading to IL-10 expression by CD4 + T cells are being elucidated, with several cytokines implicated. We explored the effect of IL-4 on the natural phenomenon of IL-10 production by a chronically stimulated antigen-specific population of differentiated Th1 cells. In vitro, IL-4 blockade inhibited while addition of exogenous IL-4 to Th1 cultures enhanced IL-10 production. In the in vivo setting of peptide immunotherapy leading to a chronically stimulated Th1 phenotype, lack of IL-4Rα inhibited the induction of IL-10. Exploring the interplay of Th1 and Th2 cells through co-culture, Th2-derived IL-4 promoted IL-10 expression by Th1 cultures, reducing their pathogenicity in vivo. Co-culture led to upregulated c-Maf expression with no decrease in the proportion of T-bet + cells in these cultures. Addition of IL-4 also reduced the encephalitogenic capacity of Th1 cultures. These data demonstrate that IL-4 contributes to IL-10 production and that Th2 cells modulate Th1 cultures towards a self-regulatory phenotype, contributing to the cross-regulation of Th1 and Th2 cells. These findings are important in the context of Th1 driven diseases since they reveal how the Th1 phenotype and function can be modulated by IL-4.

11th International Conference on Multimedia and Ubiquitous Engineering & 12th International Conference on Future Information Technology

CERN Document Server

Chen, Shu-Ching; Choo, Kim-Kwang

2017-01-01

This book presents the proceedings of the 11th International Conference on Multimedia and Ubiquitous Engineering (MUE2017) and the 12th International Conference on Future Information Technology (FutureTech2017), held in Seoul, South Korea on May 22–24, 2017. These two conferences provided an opportunity for academic and industrial professionals to discuss recent advances in the area of multimedia and ubiquitous environments including models and systems, new directions, and novel applications associated with the utilization and acceptance of ubiquitous computing devices and systems. The resulting papers address the latest technological innovations in the fields of digital convergence, multimedia convergence, intelligent applications, embedded systems, mobile and wireless communications, bio-inspired computing, grid and cloud computing, semantic web, user experience, HCI, and security and trust computing. The book offers a valuable resource for a broad readership, including students, academic researchers, and...

Dynamic fracture toughness of ASME SA508 Class 2a ASME SA533 grade A Class 2 base and heat affected zone material and applicable weld metals

International Nuclear Information System (INIS)

Logsdon, W.A.; Begley, J.A.; Gottshall, C.L.

1978-03-01

The ASME Boiler and Pressure Vessel Code, Section III, Article G-2000, requires that dynamic fracture toughness data be developed for materials with specified minimum yield strengths greater than 50 ksi to provide verification and utilization of the ASME specified minimum reference toughness K/sub IR/ curve. In order to qualify ASME SA508 Class 2a and ASME SA533 Grade A Class 2 pressure vessel steels (minimum yield strengths equal 65 kip/in. 2 and 70 kip/in. 2 , respectively) per this requirement, dynamic fracture toughness tests were performed on these materials. All dynamic fracture toughness values of SA508 Class 2a base and HAZ material, SA533 Grade A Class 2 base and HAZ material, and applicable weld metals exceeded the ASME specified minimum reference toughness K/sub IR/ curve

9th Mining and metallurgy international congress, Leon, 24-28 May 1994

International Nuclear Information System (INIS)

1994-01-01

The 9th Mining and Metallurgy International Congress had 201 communications. These was articulated into 4th areas: 1.- Geological resources management and profit: 1.1- Geological and mining research on geologic resources. 1.2.- Non energetic mineral resources exploitation. 1.3- Hydro-geologic and geothermia resources. 1.4- Geologic resources and planning. 2.- Energy: 2.1.- Energetic mining.- 2.2 Oil and gas. 2.3.- Electricity production and distribution. 2.4.- Coal clean technologies. 2.5.- Energetic management. 3.- Material engineering: 3.1.- Minerallurgia and metallurgic processes. 3.2- Industrial minerals and ornamental 10cks. 3.3 .- Building materials. 3.4 Advanced technology materials. 4.- Environmental and territorial engineering in basic industry. 4.1.-Valuation of environmental impacts. 4.2.- Restoration engineering in mining. 4.3.- Effluent and residue engineering. 4.4.- Environmental management and clean technologies 4.5.- Natural and technological risks

Functional and Logic Programming - 14th International Symposium (FLOPS 2018)

DEFF Research Database (Denmark)

This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018......This volume contains the proceedings of the 14th International Symposium on Functional and Logic Programming - FLOPS 2018 - held in Nagoya, Japan, May 9 - 11, 2018...

9th International Robotic Sailing Conference

CERN Document Server

Cruz, Nuno

2017-01-01

This book contains selected papers that address a variety of topics related to the design, development and operation of unmanned and fully autonomous sailing boats. These papers were presented in the 9th International Robotic Sailing Conference, in association with the 9th World Robotic Sailing Championship that took place in Viana do Castelo, Portugal from the 5th to 10th of September 2016. The book is divided in three parts, each focusing on key aspects of robotic sailing. The first part addresses the design, construction and validation of autonomous sailboat platforms, including their rigs, appendages and control mechanisms. The second part is devoted to the development of sensors and algorithms to enhance the performance of robotic sailing boats, in terms of their speed, course control and manoeuvring ability. Finally, the papers in the last part are dedicated to the improvement of behaviours required for the accomplishment of complex autonomous missions. Robotic sailing is a relatively new multidisciplin...

Penetration of ASM 981 in canine skin: a comparative study.

Science.gov (United States)

Gutzwiller, Meret E Ricklin; Reist, Martin; Persohn, Elke; Peel, John E; Roosje, Petra J

2006-01-01

ASM 981 has been developed for topical treatment of inflammatory skin diseases. It specifically inhibits the production and release of pro-inflammatory cytokines. We measured the skin penetration of ASM 981 in canine skin and compared penetration in living and frozen skin. To make penetration of ASM 981 visible in dog skin, tritium labelled ASM 981 was applied to a living dog and to defrosted skin of the same dog. Using qualitative autoradiography the radioactive molecules were detected in the lumen of the hair follicles until the infundibulum, around the superficial parts of the hair follicles and into a depth of the dermis of 200 to 500 microm. Activity could not be found in deeper parts of the hair follicles, the dermis or in the sebaceous glands. Penetration of ASM 981 is low in canine skin and is only equally spread in the upper third of the dermis 24 hours after application. Penetration in frozen skin takes even longer than in living canine skin but shows the same distribution.

ASME factory authorization system and the situation in Japan

International Nuclear Information System (INIS)

Futagawa, Kiyoshi

1978-01-01

Since about three or four years ago, the enterprises of machinery, iron and steel and welding materials in Japan are paying much attention to the acquisition of ASME (American Society of Mechanical Engineers) certificates or authorization to stamp the code symbols. That is, over 70 factories in Japan have undergone ASME examination, and consequently acquired the authorization or certificates. Such authorization is divided into over 20 kinds, of which about 7 are possessed by the companies in Japan. In nuclear field, the kinds of authorization are N (nuclear vessel), NPT (nuclear vessel parts), NV (nuclear vessel safety valve), and MM (material manufacturing). In non-nuclear fields, they are S (power boilers), U (pressure vessels, in Div. 1), and U2 (pressure vessels in Div. 2). The following matters are described: ASME setup, authorization procedures of ASME for factories, the kinds of authorization, factories in Japan holding the authorization or certificates, and renewal of the authorization. (Mori, K.)

5th International Conference on Cryocoolers

CERN Document Server

1989-01-01

The Cryocoolers 5 proceedings archives the contributions of leading international experts at the 5th International Cryocooler Conference that was held in Monterey, California on August 18-19, 1988. The authors submitted twenty six papers describing advancements and applications of cryocoolers in the temperature range below 80K. This year's conference was hosted by the U.S. Naval Postgraduate School in Monterey, California, and the conference proceedings reproduced here were published by the Wright-Patterson AFB in Ohio.

Statistical analysis of the ASME KIc database

International Nuclear Information System (INIS)

Sokolov, M.A.

1998-01-01

The American Society of Mechanical Engineers (ASME) K Ic curve is a function of test temperature (T) normalized to a reference nil-ductility temperature, RT NDT , namely, T-RT NDT . It was constructed as the lower boundary to the available K Ic database. Being a lower bound to the unique but limited database, the ASME K Ic curve concept does not discuss probability matters. However, a continuing evolution of fracture mechanics advances has led to employment of the Weibull distribution function to model the scatter of fracture toughness values in the transition range. The Weibull statistic/master curve approach was applied to analyze the current ASME K Ic database. It is shown that the Weibull distribution function models the scatter in K Ic data from different materials very well, while the temperature dependence is described by the master curve. Probabilistic-based tolerance-bound curves are suggested to describe lower-bound K Ic values

13th International Congress on Polymers in Concrete

OpenAIRE

Aguiar, J. L. Barroso de, ed. lit.; Jalali, Said, ed. lit.; Camões, Aires, ed. lit; Ferreira, Rui Miguel, ed. lit.; International Congress on Polymers in Concrete, 13, Madeira, 2010

2010-01-01

The 13th International Congress on Polymers in Concrete 2010 (13th ICPIC 2010) follows a series of 12 earlier successful congresses, which has been started in London in 1975. These congresses, being held every three years, played a key role in disseminating R&D findings between researchers, academics, industrials and students. The 13th ICPIC was again a forum to exchange knowledge and most recent research findings among participants. It represented a contribution to the development of this im...

15th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2009-01-01

This is the 15th volume in the conference series. Over the years the International Cryocooler Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

14th International Cryocooler Conference

CERN Document Server

Ross, Ronald G

2007-01-01

This is the 14th volume in the conference series. Over the years the International Cryocoolers Conference has become the preeminent worldwide conference for the presentation of the latest developments and test experiences with cryocoolers. The typical applications of this technology include cooling space and terrestrial infrared focal plane arrays, space x-ray detectors, medical applications, and a growing number of high-temperature superconductor applications.

Highlights of proposed changes to ANSI/ASME N509-80

International Nuclear Information System (INIS)

Ornberg, S.C.

1987-01-01

The ASME Committee on Nuclear Air and Gas Treatment (CONAGT) are at the time of this writing considering performing maintenance revisions of ANSI N509 and N510 based on the results of a required 5-year review and comments received from users of the standards at workshops and through inquiries. This paper discusses the highlights of the significant revisions to ANSI/ASME N509 and explains the reasons for the changes. It should be emphasized that these revisions are not yet approved by ASME CONAGT, the board of Nuclear Codes and Standards, or ANSI

International Geomagnetic Reference Field: the 12th generation

DEFF Research Database (Denmark)

Thébault, Erwan; Finlay, Chris; Beggan, Ciarán D.

2015-01-01

The 12th generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014 by the Working Group V-MOD appointed by the International Association of Geomagnetism and Aeronomy (IAGA). It updates the previous IGRF generation with a definitive main field model for epoch ...

Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals.

Science.gov (United States)

Mincewicz, Grzegorz; Rumiński, Jacek; Krzykowski, Grzegorz

2012-02-01

Recently, we described a model system which included corrections of high-resolution computed tomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM). To verify the clinical application of ASM by comparing bronchial measurements obtained by means of the traditional eye-driven method, subpixel method alone and ASM in a group comprised of bronchial asthma patients and healthy individuals. The study included 30 bronchial asthma patients and the control group comprised of 20 volunteers with no symptoms of asthma. The lowest internal and external diameters of the bronchial cross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1) traditional eye-driven method, (2) subpixel technique, and (3) ASM. In the case of the eye-driven method, lower ID values along with lower bronchial lumen area and its percentage ratio to total bronchial area were basic parameters that differed between asthma patients and healthy controls. In the case of the subpixel method and ASM, both groups were not significantly different in terms of ID. Significant differences were observed in values of ED and total bronchial area with both parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%. Results obtained in this study suggest that the traditional eye-driven method of HRCT-based measurement of bronchial tree components probably overstates the degree of bronchial patency in asthma patients. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals

International Nuclear Information System (INIS)

Mincewicz, Grzegorz; Rumiński, Jacek; Krzykowski, Grzegorz

2012-01-01

Background: Recently, we described a model system which included corrections of high-resolution computed tomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM). Objective: To verify the clinical application of ASM by comparing bronchial measurements obtained by means of the traditional eye-driven method, subpixel method alone and ASM in a group comprised of bronchial asthma patients and healthy individuals. Methods: The study included 30 bronchial asthma patients and the control group comprised of 20 volunteers with no symptoms of asthma. The lowest internal and external diameters of the bronchial cross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1) traditional eye-driven method, (2) subpixel technique, and (3) ASM. Results: In the case of the eye-driven method, lower ID values along with lower bronchial lumen area and its percentage ratio to total bronchial area were basic parameters that differed between asthma patients and healthy controls. In the case of the subpixel method and ASM, both groups were not significantly different in terms of ID. Significant differences were observed in values of ED and total bronchial area with both parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%. Conclusions: Results obtained in this study suggest that the traditional eye-driven method of HRCT-based measurement of bronchial tree components probably overstates the degree of bronchial patency in asthma patients.

Simulation and optimization of a coking wastewater biological treatment process by activated sludge models (ASM).

Science.gov (United States)

Wu, Xiaohui; Yang, Yang; Wu, Gaoming; Mao, Juan; Zhou, Tao

2016-01-01

Applications of activated sludge models (ASM) in simulating industrial biological wastewater treatment plants (WWTPs) are still difficult due to refractory and complex components in influents as well as diversity in activated sludges. In this study, an ASM3 modeling study was conducted to simulate and optimize a practical coking wastewater treatment plant (CWTP). First, respirometric characterizations of the coking wastewater and CWTP biomasses were conducted to determine the specific kinetic and stoichiometric model parameters for the consecutive aeration-anoxic-aeration (O-A/O) biological process. All ASM3 parameters have been further estimated and calibrated, through cross validation by the model dynamic simulation procedure. Consequently, an ASM3 model was successfully established to accurately simulate the CWTP performances in removing COD and NH4-N. An optimized CWTP operation condition could be proposed reducing the operation cost from 6.2 to 5.5 €/m(3) wastewater. This study is expected to provide a useful reference for mathematic simulations of practical industrial WWTPs. Copyright © 2015 Elsevier Ltd. All rights reserved.

Proposal to support the 4th international conference on nitrification and related processes (ICoN4)

Energy Technology Data Exchange (ETDEWEB)

Klotz, Martin Gunter [Univ. of North Carolina, Charlotte, NC (United States)

2016-11-04

The 4th International Conference on Nitrification and Related Processes (ICoN4) commencing between June 27 and July 1, 2015, at the University of Alberta in Edmonton, Alberta, Canada brings together an international collection of academic, government, and private sector researchers of the global biogeochemical nitrogen cycle to share their scientific discoveries, innovations and pertinent societal impacts. The classical understanding of “nitrification” describes the two-step transformation of ammonium to nitrite and nitrite to nitrate; however, we now know from the analysis genome sequences, the application of ‘omics technologies, microbial ecology, biogeochemistry, and microbial physiology that the transformation of ammonium is not performed by a few particular groups of microorganisms nor is it confined to oxic environments. Past ICoN meetings have explored the interconnections between ammonium- and nitrite-consuming processes in all ecosystems, the emission of greenhouse gases by these processes and their control, and the intersection between intermediates of the nitrification process and other elemental cycles; this has generated tremendous progress in our understanding of the global nitrogen cycle and it has generated excitement in the next generation of N cycle researchers. Nitrification research has a long-standing connection to the Community Science Program of the DOE. Between 1999 and 2001, the JGI generated the first genome sequence of an ammonia-oxidizing bacterium, Nitrosomonas europaea ATCC 19718, and it has subsequently sequenced, or is in the process of sequencing over 50 additional genomes from ammonia-oxidizing bacteria, nitrite-oxidizing bacteria, and ammonia-oxidizing archaea. Autotrophic ammonia- and nitrite-transforming microorganisms play also a critical role in carbon cycling and sequestration in nearly all ecosystems. Not only do they control the concentration and speciation of biologically available N to plants and other

Proposal to support the 4th international conference on nitrification and related processes (ICoN4)

International Nuclear Information System (INIS)

Klotz, Martin Gunter

2016-01-01

The 4th International Conference on Nitrification and Related Processes (ICoN4) commencing between June 27 and July 1, 2015, at the University of Alberta in Edmonton, Alberta, Canada brings together an international collection of academic, government, and private sector researchers of the global biogeochemical nitrogen cycle to share their scientific discoveries, innovations and pertinent societal impacts. The classical understanding of “nitrification” describes the two-step transformation of ammonium to nitrite and nitrite to nitrate; however, we now know from the analysis genome sequences, the application of ‘omics technologies, microbial ecology, biogeochemistry, and microbial physiology that the transformation of ammonium is not performed by a few particular groups of microorganisms nor is it confined to oxic environments. Past ICoN meetings have explored the interconnections between ammonium- and nitrite-consuming processes in all ecosystems, the emission of greenhouse gases by these processes and their control, and the intersection between intermediates of the nitrification process and other elemental cycles; this has generated tremendous progress in our understanding of the global nitrogen cycle and it has generated excitement in the next generation of N cycle researchers. Nitrification research has a long-standing connection to the Community Science Program of the DOE. Between 1999 and 2001, the JGI generated the first genome sequence of an ammonia-oxidizing bacterium, Nitrosomonas europaea ATCC 19718, and it has subsequently sequenced, or is in the process of sequencing over 50 additional genomes from ammonia-oxidizing bacteria, nitrite-oxidizing bacteria, and ammonia-oxidizing archaea. Autotrophic ammonia- and nitrite-transforming microorganisms play also a critical role in carbon cycling and sequestration in nearly all ecosystems. Not only do they control the concentration and speciation of biologically available N to plants and other

10th International Geostatistics Congress

CERN Document Server

Rodrigo-Ilarri, Javier; Rodrigo-Clavero, María; Cassiraga, Eduardo; Vargas-Guzmán, José

2017-01-01

This book contains selected contributions presented at the 10th International Geostatistics Congress held in Valencia from 5 to 9 September, 2016. This is a quadrennial congress that serves as the meeting point for any engineer, professional, practitioner or scientist working in geostatistics. The book contains carefully reviewed papers on geostatistical theory and applications in fields such as mining engineering, petroleum engineering, environmental science, hydrology, ecology, and other fields.

13th International Conference on X-Ray Lasers

CERN Document Server

Gautier, Julien; Ros, David; Zeitoun, Philippe

2014-01-01

These proceedings comprise of invited and contributed papers presented at the 13th International Conference on X-Ray Lasers (ICXRL 2012) which was held 11–15 June 2012 in Paris, in the famous Quartier Latin, inside the historical Center of Cordeliers. This conference is part of a continuing series dedicated to recent developments and applications of x-ray lasers and other coherent x-ray sources with attention to supporting technologies and instrumentation. New results in the generation of intense, coherent x-rays and progress towards practical devices and their applications are reported in these proceedings, including areas of research in plasma-based x-ray lasers, 4th generation accelerator-based sources and higher harmonic generation. Recent achievements related to the increase of the repetition rate up to 100 Hz and shorter wavelength collisional plasma-based soft x-ray lasers down to about 7 nm are presented. Seeding the amplifying plasma with a femtosecond high-order harmonic of infrared laser was fore...

14th International Conference on X-Ray Lasers

CERN Document Server

Menoni, Carmen; Marconi, Mario

2016-01-01

These proceedings comprise invited and contributed papers presented at the 14th International Conference on X-Ray Lasers (ICXRL 2014). This conference is part of a continuing series dedicated to recent developments and applications of x-ray lasers and other coherent x-ray sources with attention to supporting technologies and instrumentation. New results in the generation of intense, coherent x-rays and progress toward practical devices and their applications in numerous fields are reported. Areas of research in plasma-based x-ray lasers, 4th generation accelerator-based sources and higher harmonic generation, and other x-ray generation schemes are covered.  The scope of ICXRL 2014 included, but was not limited to: Laser-pumped X-ray lasers Discharge excitation and other X-ray laser pumping methods Injection/seeding of X-ray amplifiers New lasing transitions and novel X-ray laser schemes High Harmonic sources-Free-electron laser generation in the XUV and X-ray range Novel schemes for coherent XUV and X-ray ge...

Low appendicular skeletal muscle mass (ASM) with limited mobility and poor health outcomes in middle-aged African Americans.

Science.gov (United States)

Malmstrom, Theodore K; Miller, Douglas K; Herning, Margaret M; Morley, John E

2013-09-01

Recent efforts to provide a consensus definition propose that sarcopenia be considered a clinical syndrome associated with the loss of both skeletal muscle mass and muscle function that occurs with aging. Validation of sarcopenia definitions that include both low muscle mass and poor muscle function is needed. In the population-based African American Health (AAH) study (N = 998 at baseline/wave 1), muscle mass and mobility were evaluated in a clinical testing center in a subsample of N = 319 persons (ages 52-68) at wave 4 (2004). Muscle mass was measured using dual energy x-ray absorptiometry and mobility by a 6-min walk test and 4-m gait walk test. Height corrected appendicular skeletal mass (ASM; 9.0 ± 1.5 in n = 124 males, 8.3 ± 2.2 in n = 195 females) was computed as total lean muscle mass in arms and legs (kilograms) divided by the square of height (meters). Cross-sectional and longitudinal (6-year) associations of low ASM (bottom 25 % AAH sample; ASM with limited mobility (4-m gait walk ≤1 m/s or 6-min walk ASM with limited mobility was associated with IADL difficulties (p = .008) and frailty (p = .040) but not with ADL difficulties or falls in cross-sectional analyses; and with ADL difficulties (p = .022), IADL difficulties (p = .006), frailty (p = .039), and mortality (p = .003) but not with falls in longitudinal analyses adjusted for age and gender. Low ASM alone was marginally associated with mortality (p = .085) but not with other outcomes in cross-sectional or longitudinal analyses. Low ASM with limited mobility is associated with poor health outcomes among late middle-aged African Americans.

Equilíbrio corporal em crianças e adolescentes asmáticos e não asmáticos

Directory of Open Access Journals (Sweden)

Marta Cristina Rodrigues da Silva

2013-06-01

Full Text Available O objetivo foi analisar e comparar o equilíbrio corporal em crianças e adolescentes asmáticos e não asmáticos. Fizeram parte do grupo de estudos 24 sujeitos com idades de 7 a 14 anos divididos em dois grupos: grupo asmático e grupo controle. Para avaliação do equilíbrio corporal utilizou-se uma plataforma de força. Foram utilizadas as condições, olhos abertos e fechados com três tentativas aleatórias, com duração de 30 segundos cada uma. Os resultados apontaram diferença significativa entre os grupos, no teste de equilíbrio com olhos abertos apresentando maior amplitude de deslocamento na direção ântero-posterior (COPap (p = 0,04, e médio lateral (COPml (p = 0,02 no grupo asmático. Enquanto que no teste com olhos fechados a diferença foi significante apenas na amplitude de deslocamento ântero-posterior (COPap (p = 0,02 e Área de Elipse (p=0,03. Desse modo, a asma com suas limitações e consequências parece influenciar negativamente no equilíbrio corporal de seus portadores quando comparados com crianças sem a patologia e da mesma faixa etária.

Differential diagnosis of the 4th ventricular tumors

International Nuclear Information System (INIS)

Lee, Sang Woo; Lee, Jong Min; Kang, Moo Song; Kim, Chul Min; Kim, Chang Soo

1997-01-01

To determine by analysis of MR and CT findings the points of differentiation among 4th ventricular tumors, especially the change of shape of the 4th ventricle caused by the site at which 4th ventricular tumors originate. The authors retrospectively analyzed and compared the CT(n=5) and MRI(n=12) findings of 13 pathologically proven 4th ventricular tumors comprising six medulloblastomas three ependymomas(4 cases) and three choroids plexus papillomas. On axial MRI medulloblastomas showed anterior and anterolateral CSF-clefts between the tumor mass and the 4th ventricular wall in one and five cases, respectively; on sagittal MRI, anterior beaking of the upper 4th ventricle was seen. Two ependymomas showed posterolateral CSF-cleft on axial MRI and posterior beaking of the upper 4th ventricle on sagittal MRI. Two ependymomas and all choroids plexus papillomas showed anterior, posterior and lateral CSF-clefts on axial MRI, and anterior and posterior beakings of the upper 4th ventricle on sagittal MRI. On Gd-DTPA enhanced T1WI, all medulloblastomas and ependymomas showed inhomogeneous enhancement, and all choroids plexus papillomas showed homogeneous enhancement. On CT, tow choroids plexus papillomas showed dense calcifications. The differential diagnosis of 4th ventricular tumors can be preoperatively suggested by analysis of findings such as a CSF-cleft between the tumor mass and the 4th ventricular wall on axial MR and CT images, the shape of the upper 4th ventricle on sagittal MRI, contrast enhancement pattern, necrosis and cyst, and CSF seeding

Consideration of the Construction Code for TBM-body in ASME BPVC

International Nuclear Information System (INIS)

Kim, Dongjun; Kim, Yunjae; Kim, Suk Kwon; Park, Sung Dae; Lee, Dong Won

2016-01-01

In this paper, ASME code is briefly introduced, and the TBM-body is classified for selecting the ASME section. With the classification of TBM-body, the appropriate section is determined. Helium Cooled Ceramic Reflector (HCCR) Test Blanket System (TBS) has been designed to research on the functions of breeding blanket by KO TBM team. The functions has three subjects as 1) Tritium breeding, 2) Heat conversion and extraction, and 3) Neutron and Gamma-ray shielding. For the process of design, it is needed to select the appropriate construction code as the design criteria. ITER Organization (IO) has proposed that RCC-MR Edition 2007 ver. shall be used for TBM-shield. Because the TBM-shield is connected to the vacuum boundary. For the other part of TBM-set, TBM-body, there is no constraint on the selected code, and the manufacturer can appropriately select the construction code to apply design and fabrication parts. KO TBM Team has considered whether it is appropriate to choose any code for TBM-body. One of the things is ASME code. The advantage of ASME choice is suitable to the domestic status. In the domestic nuclear plant, ASME or KEPIC code is used as regulatory requirements. Based on this, it is possible to prepare a domestic fusion plant regulatory. In this paper, the construction code of TBM-body was determined in ASME BPVC. For the determination of code, the structure of ASME BPVC was introduced and the classification for TBM-body was conducted by the ITER criteria. And the operation conditions of TBM-body that contained creep and irradiation effects was considered to determine the construction code

Consideration of the Construction Code for TBM-body in ASME BPVC

Energy Technology Data Exchange (ETDEWEB)

Kim, Dongjun; Kim, Yunjae [Korea Univ., Seoul (Korea, Republic of); Kim, Suk Kwon; Park, Sung Dae; Lee, Dong Won [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2016-10-15

In this paper, ASME code is briefly introduced, and the TBM-body is classified for selecting the ASME section. With the classification of TBM-body, the appropriate section is determined. Helium Cooled Ceramic Reflector (HCCR) Test Blanket System (TBS) has been designed to research on the functions of breeding blanket by KO TBM team. The functions has three subjects as 1) Tritium breeding, 2) Heat conversion and extraction, and 3) Neutron and Gamma-ray shielding. For the process of design, it is needed to select the appropriate construction code as the design criteria. ITER Organization (IO) has proposed that RCC-MR Edition 2007 ver. shall be used for TBM-shield. Because the TBM-shield is connected to the vacuum boundary. For the other part of TBM-set, TBM-body, there is no constraint on the selected code, and the manufacturer can appropriately select the construction code to apply design and fabrication parts. KO TBM Team has considered whether it is appropriate to choose any code for TBM-body. One of the things is ASME code. The advantage of ASME choice is suitable to the domestic status. In the domestic nuclear plant, ASME or KEPIC code is used as regulatory requirements. Based on this, it is possible to prepare a domestic fusion plant regulatory. In this paper, the construction code of TBM-body was determined in ASME BPVC. For the determination of code, the structure of ASME BPVC was introduced and the classification for TBM-body was conducted by the ITER criteria. And the operation conditions of TBM-body that contained creep and irradiation effects was considered to determine the construction code.

Crystal structures of Th(OH)PO4, U(OH)PO4 and Th2O(PO4)2. Condensation mechanism of M(IV)(OH)PO4 (M= Th, U) into M2O(PO4)2

International Nuclear Information System (INIS)

Dacheux, N.; Clavier, N.; Wallez, G.; Quarton, M.

2007-01-01

Three new crystal structures, isotypic with β-Zr 2 O(PO 4 ) 2 , have been resolved by the Rietveld method. All crystallize with an orthorhombic cell (S.G.: Cmca) with a = 7.1393(2) Angstroms, b = 9.2641(2) Angstroms, c 12.5262(4) Angstroms, V = 828.46(4) (Angstroms) 3 and Z = 8 for Th(OH)PO 4 ; a = 7.0100(2) Angstroms, b = 9.1200(2) Angstroms, c = 12.3665(3) Angstroms, V 790.60(4) (Angstroms) 3 and Z = 8 for U(OH)PO 4 ; a 7.1691(3) Angstroms, b 9.2388(4) Angstroms, c = 12.8204(7) Angstroms, V 849.15(7) (Angstroms) 3 and Z = 4 for Th 2 O(PO 4 ) 2 . By heating, the M(OH)PO 4 (M Th, U) compounds condense topotactically into M 2 O(PO 4 ) 2 , with a change of the environment of the tetravalent cation that lowers from 8 to 7 oxygen atoms. The lower stability of Th 2 O(PO 4 ) 2 compared to that of U 2 O(PO 4 ) 2 seems to result from this unusual environment for tetravalent thorium. (authors)

9th International Symposium on Intelligent Distributed Computing

CERN Document Server

Camacho, David; Analide, Cesar; Seghrouchni, Amal; Badica, Costin

2016-01-01

This book represents the combined peer-reviewed proceedings of the ninth International Symposium on Intelligent Distributed Computing – IDC’2015, of the Workshop on Cyber Security and Resilience of Large-Scale Systems – WSRL’2015, and of the International Workshop on Future Internet and Smart Networks – FI&SN’2015. All the events were held in Guimarães, Portugal during October 7th-9th, 2015. The 46 contributions published in this book address many topics related to theory and applications of intelligent distributed computing, including: Intelligent Distributed Agent-Based Systems, Ambient Intelligence and Social Networks, Computational Sustainability, Intelligent Distributed Knowledge Representation and Processing, Smart Networks, Networked Intelligence and Intelligent Distributed Applications, amongst others.

13th International Conference on Information Technology

CERN Document Server

2016-01-01

This book collects articles presented at the 13th International Conference on Information Technology- New Generations, April, 2016, in Las Vegas, NV USA. It includes over 100 chapters on critical areas of IT including Web Technology, Communications, Security, and Data Mining.

9th International Conference on Multimedia and Ubiquitous Engineering and the 10th International Conference on Future Information Technology

CERN Document Server

Chao, Han-Chieh; Arabnia, Hamid; Yen, Neil; Advanced Multimedia and Ubiquitous Engineering : Future Information Technology; MUE-15; FutureTech 2015

This volume brings together contributions representing the state-of-the-art in new multimedia and future technology information research, currently a major topic in computer science and electronic engineering. Researchers aim to interoperate multimedia frameworks, transforming the way people work and  interact with multimedia data. This book covers future information technology topics including digital and multimedia convergence, ubiquitous and pervasive computing, intelligent computing and applications, embedded systems, mobile and wireless communications, bio-inspired computing, grid and cloud computing, semantic web, human-centric computing and social networks, adaptive and context-aware computing, security and trust computing and related areas.  Representing the combined proceedings of the 9th International Conference on Multimedia and Ubiquitous Engineering (MUE-15) and the 10th International Conference on Future Information Technology (FutureTech 2015), this book aims to provide a complete coverage of...

6th International Workshop on Model Reduction in Reactive Flow

Science.gov (United States)

2018-01-01

reduction in reacting flow . Registration DateRegistration TypeFirst Name Middle NameLast Name Affiliation US State /Canadian ProvinceState/Province/R gion...Report: 6th International Workshop on Model Reduction in Reactive Flow The views, opinions and/or findings contained in this report are those of the...Agreement Number: W911NF-17-1-0121 Organization: Princeton University Title: 6th International Workshop on Model Reduction in Reactive Flow Report Term

ASME nuclear codes and standards: Recent technical initiatives

International Nuclear Information System (INIS)

Feigel, R. E.

1995-01-01

Although nuclear power construction is currently in a hiatus in the US, ASME and its volunteer committees remain committed to continual improvements in the technical requirements in its nuclear codes. This paper provides an overview of several significant recent revisions to ASME' s nuclear codes. Additionally, other important initiatives currently being addressed by ASME committees will be described. With the largest population of operating light water nuclear plants in the world and worldwide use of its nuclear codes, ASME continues to support technical advancements in its nuclear codes and standards. While revisions of various magnitude are an ongoing process, several recent revisions embody significant changes based on state of the art design philosophy and substantial industry experience. In the design area, a significant revisions has recently been approved which will significantly reduce conservatisms in seismic piping design as well as provide simplified design rules. Major revisions have also been made to the requirements for nuclear material manufacturers and suppliers, which should result in clearer understanding of this difficult administrative area of the code. In the area of Section XI inservice rules, substantial studies are underway to investigate the application of probabilistic, risked based inspection in lieu of the current deterministic inspection philosophy. While much work still is required in this area, it is an important potential application of the emerging field of risk based inspection

SPECIAL ISSUE VETERINARY IMMUNOLOGY IMMUNOPATHOLOGY: PROCEEDINGS 8TH INTERNATIONAL VETERINARY IMMUNOLOGY SYMPOSIUM

Science.gov (United States)

This is the Special Issue of Vet. Immunol. Immunopathol. that summarizes the 8th International Veterinary Immunology Symposium (8 th IVIS) held August 15th-19th, 2007, in Ouro Preto, Brazil. The 8 th IVIS highlighted the importance of veterinary immunology for animal health, vaccinology, reproducti...

7th International Conference of Political Economy

OpenAIRE

BEKEN, Gülçin

2016-01-01

Abstract. In this study, the 7th International Conference of Political Economy in İstanbul was evaluated. This year it  was organized by Marmara University Faculty of Economics and Batman University Faculty of Economics and Administrative Sciences with the cooperation of their international supporters all over the world. These conference series are said to be successful to bring all the scholars, academicians, students, and volunteers who are interested in political economy. Starting from 200...

11th International Conference Mechatronics

CERN Document Server

Brezina, Tomas

2016-01-01

Focusing on the most rapidly changing areas of mechatronics, this book discusses signals and system control, mechatronic products, metrology and nanometrology, automatic control & robotics, biomedical engineering, photonics, design manufacturing and testing of MEMS. It is reflected in the list of contributors, including an international group of 302 leading researchers representing 12 countries. The book is intended for use in academic, government and industry R&D departments, as an indispensable reference tool for the years to come. Thid volume can serve a global community as the definitive reference source in Mechatronics. The book comprises carefully selected 93 contributions presented at the 11th International Conference Mechatronics 2015, organized by Faculty of Mechatronics, Warsaw University of Technology, on September 21-23, in Warsaw, Poland. .

4th International Geostatistics Congress

CERN Document Server

1993-01-01

The contributions in this book were presented at the Fourth International Geostatistics Congress held in Tróia, Portugal, in September 1992. They provide a comprehensive account of the current state of the art of geostatistics, including recent theoretical developments and new applications. In particular, readers will find descriptions and applications of the more recent methods of stochastic simulation together with data integration techniques applied to the modelling of hydrocabon reservoirs. In other fields there are stationary and non-stationary geostatistical applications to geology, climatology, pollution control, soil science, hydrology and human sciences. The papers also provide an insight into new trends in geostatistics particularly the increasing interaction with many other scientific disciplines. This book is a significant reference work for practitioners of geostatistics both in academia and industry.

12th International Symposium Continuous Surface Mining

CERN Document Server

2015-01-01

This edited volume contains research results presented at the 12th International Symposium Continuous Surface Mining, ISCSM Aachen 2014. The target audience primarily comprises researchers in the lignite mining industry and practitioners in this field but the book may also be beneficial for graduate students.

Simulation of municipal-industrial full scale WWTP in an arid climate by application of ASM3

Directory of Open Access Journals (Sweden)

Abdelsalam Elawwad

2017-03-01

Full Text Available In developing countries, and due to the high cost of treatment of industrial wastewater, municipal wastewater treatment facilities usually receive a mixture of municipal wastewater and partially treated industrial wastewater. As a result, an increased potential for shock loads with high pollutant concentrations is expected. The use of mathematical modelling of wastewater treatment is highly efficient in such cases. A dynamic model based on activated sludge model no. 3 (ASM3 describing the performance of the activated sludge process at a full scale wastewater treatment plant (WWTP receiving mixed domestic–industrial wastewater located in an arid area is presented. ASM3 was extended by adding the Arrhenius equation to respond to changes in temperature. BioWin software V.4 was used as the model platform. The model was calibrated under steady-state conditions, adjusting only three kinetic and stoichiometric parameters: maximum heterotrophic growth rate (μH = 8 d−1, heterotrophic aerobic decay rate (bH, O2 = 0.18 d−1, and aerobic heterotrophic yield (YH,O2 = 0.4 (gCOD/gCOD. ASM3 was successful in predicting the WWTP performance, as the model was validated with 10 months of routine daily measurements. ASM3 extended with the Arrhenius equation could be helpful in the design and operation of WWTPs with mixed municipal–industrial influent in arid areas.

Analysis of the Current Technical Issues on ASME Code and Standard for Nuclear Mechanical Design(2009)

International Nuclear Information System (INIS)

Koo, Gyeong Hoi; Lee, B. S.; Yoo, S. H.

2009-11-01

This report describes the analysis on the current revision movement related to the mechanical design issues of the U.S ASME nuclear code and standard. ASME nuclear mechanical design in this report is composed of the nuclear material, primary system, secondary system and high temperature reactor. This report includes the countermeasures based on the ASME Code meeting for current issues of each major field. KAMC(ASME Mirror Committee) of this project is willing to reflect a standpoint of the domestic nuclear industry on ASME nuclear mechanical design and play a technical bridge role for the domestic nuclear industry in ASME Codes application

Analysis of the Current Technical Issues on ASME Code and Standard for Nuclear Mechanical Design(2009)

Energy Technology Data Exchange (ETDEWEB)

Koo, Gyeong Hoi; Lee, B. S.; Yoo, S. H.

2009-11-15

This report describes the analysis on the current revision movement related to the mechanical design issues of the U.S ASME nuclear code and standard. ASME nuclear mechanical design in this report is composed of the nuclear material, primary system, secondary system and high temperature reactor. This report includes the countermeasures based on the ASME Code meeting for current issues of each major field. KAMC(ASME Mirror Committee) of this project is willing to reflect a standpoint of the domestic nuclear industry on ASME nuclear mechanical design and play a technical bridge role for the domestic nuclear industry in ASME Codes application

GC-ASM: Synergistic Integration of Graph-Cut and Active Shape Model Strategies for Medical Image Segmentation.

Science.gov (United States)

Chen, Xinjian; Udupa, Jayaram K; Alavi, Abass; Torigian, Drew A

2013-05-01

Image segmentation methods may be classified into two categories: purely image based and model based. Each of these two classes has its own advantages and disadvantages. In this paper, we propose a novel synergistic combination of the image based graph-cut (GC) method with the model based ASM method to arrive at the GC-ASM method for medical image segmentation. A multi-object GC cost function is proposed which effectively integrates the ASM shape information into the GC framework. The proposed method consists of two phases: model building and segmentation. In the model building phase, the ASM model is built and the parameters of the GC are estimated. The segmentation phase consists of two main steps: initialization (recognition) and delineation. For initialization, an automatic method is proposed which estimates the pose (translation, orientation, and scale) of the model, and obtains a rough segmentation result which also provides the shape information for the GC method. For delineation, an iterative GC-ASM algorithm is proposed which performs finer delineation based on the initialization results. The proposed methods are implemented to operate on 2D images and evaluated on clinical chest CT, abdominal CT, and foot MRI data sets. The results show the following: (a) An overall delineation accuracy of TPVF > 96%, FPVF ASM for different objects, modalities, and body regions. (b) GC-ASM improves over ASM in its accuracy and precision to search region. (c) GC-ASM requires far fewer landmarks (about 1/3 of ASM) than ASM. (d) GC-ASM achieves full automation in the segmentation step compared to GC which requires seed specification and improves on the accuracy of GC. (e) One disadvantage of GC-ASM is its increased computational expense owing to the iterative nature of the algorithm.

6th International Workshop on Application of Lasers in Atomic Nuclei Research

CERN Document Server

Błaszczak, Z; Marinova, K; LASER 2004

2006-01-01

6th International Workshop on Application of Lasers in Atomic Nuclei Research, LASER 2004, held in Poznan, Poland, 24-27 May, 2004 Researchers and graduate students interested in the Mössbauer Effect and its applications will find this volume indispensable. The volume presents the most recent developments in the methodology of Mössbauer spectroscopy. Reprinted from Hyperfine Interactions (HYPE) Volume 162, 1-4

Operating nuclear plant feedback to ASME and French codes

International Nuclear Information System (INIS)

Journet, J.; O'Donnell, W.J.

1996-01-01

The French have an advantage in nuclear plant operating experience feedback due to the highly centralized nature of their nuclear industry. There is only one utility in charge of design as well as operations (EDF) and only one reactor vendor (Framatome). The ASME Code has played a key role in resolving technical issues in the design and operation of nuclear plants since the inception of nuclear power. The committee structure of the Code brings an ideal combination of senior technical people with both broad and specialized experience to bear on complex how safe is safe enough technical issues. The authors now see an even greater role for the ASME Code in a proposed new regulatory era for the US nuclear industry. The current legalistic confrontational regulatory era has been quite destructive. There now appears to be a real opportunity to begin a new era of technical consensus as the primary means for resolving safety issues. This change can quickly be brought about by having the industry take operating plant problems and regulatory technical issues directly to the ASME Code for timely resolution. Surprisingly, there is no institution in the US nuclear industry with such a mandate. In fact, the industry is organized to feedback through the Nuclear Regulatory Commission issues which could be far better resolved through the ASME Code. Major regulatory benefits can be achieved by closing this loop and providing systematic interaction with the ASME Code. The essential elements of a new regulatory era and ideas for organizing US institutional industry responsibilities, taken from the French experience, are described in this paper

International pressure vessels and piping codes and standards. Volume 2: Current perspectives; PVP-Volume 313-2

International Nuclear Information System (INIS)

Rao, K.R.; Asada, Yasuhide; Adams, T.M.

1995-01-01

The topics in this volume include: (1) Recent or imminent changes to Section 3 design sections; (2) Select perspectives of ASME Codes -- Section 3; (3) Select perspectives of Boiler and Pressure Vessel Codes -- an international outlook; (4) Select perspectives of Boiler and Pressure Vessel Codes -- ASME Code Sections 3, 8 and 11; (5) Codes and Standards Perspectives for Analysis; (6) Selected design perspectives on flow-accelerated corrosion and pressure vessel design and qualification; (7) Select Codes and Standards perspectives for design and operability; (8) Codes and Standards perspectives for operability; (9) What's new in the ASME Boiler and Pressure Vessel Code?; (10) A look at ongoing activities of ASME Sections 2 and 3; (11) A look at current activities of ASME Section 11; (12) A look at current activities of ASME Codes and Standards; (13) Simplified design methodology and design allowable stresses -- 1 and 2; (14) Introduction to Power Boilers, Section 1 of the ASME Code -- Part 1 and 2. Separate abstracts were prepared for most of the individual papers

ASME method for particle reconstruction

International Nuclear Information System (INIS)

Ierusalimov, A.P.

2009-01-01

The method of approximate solution of motion equation (ASME) was used to reconstruct the parameters for charged particles. It provides a good precision for momentum, angular and space parameters of particles in coordinate detectors. The application of the method for CBM, HADES and MPD/NICA setups is discussed

The Leap into 4th Grade

Science.gov (United States)

Anderson, Mike

2011-01-01

Fourth grade is a pivotal year, in which students commonly face increased academic demands. According to Anderson, teachers can help students make a smooth transition to 4th grade by introducing these new challenges in ways that are in line with 4th graders' common developmental characteristics: incredible energy and emotion, industriousness and…

15th International Symposium of Robotic Research

CERN Document Server

Khatib, Oussama

2017-01-01

This volume presents a collection of papers presented at the 15th International Symposium of Robotic Research (ISRR). ISRR is the biennial meeting of the International Foundation of Robotic Research (IFRR) and its 15th edition took place in Flagstaff, Arizona on December 9 to December 12, 2011. As for the previous symposia, ISRR 2011 followed up on the successful concept of a mixture of invited contributions and open submissions. Therefore approximately half of the 37 contributions were invited contributions from outstanding researchers selected by the IFRR officers and the program committee, and the other half were chosen among the open submissions after peer review. This selection process resulted in a truly excellent technical program which featured some of the very best of robotic research. The program was organized around oral presentation in a single-track format and included for the first time a small number of interactive presentations. The symposium contributions contained in this volume report on a ...

10th International Symposium on Intelligent Distributed Computing

CERN Document Server

Seghrouchni, Amal; Beynier, Aurélie; Camacho, David; Herpson, Cédric; Hindriks, Koen; Novais, Paulo

2017-01-01

This book presents the combined peer-reviewed proceedings of the tenth International Symposium on Intelligent Distributed Computing (IDC’2016), which was held in Paris, France from October 10th to 12th, 2016. The 23 contributions address a range of topics related to theory and application of intelligent distributed computing, including: Intelligent Distributed Agent-Based Systems, Ambient Intelligence and Social Networks, Computational Sustainability, Intelligent Distributed Knowledge Representation and Processing, Smart Networks, Networked Intelligence and Intelligent Distributed Applications, amongst others.

International Geomagnetic Reference Field: the 12th generation

OpenAIRE

Thébault , Erwan; Finlay , Christopher ,; Beggan , Ciarán ,; Alken , Patrick; Aubert , Julien ,; Barrois , Olivier; Bertrand , François; Bondar , Tatiana; Boness , Axel; Brocco , Laura; Canet , Elisabeth ,; Chambodut , Aude; Chulliat , Arnaud ,; Coïsson , Pierdavide ,; Civet , François

2015-01-01

International audience; The 12th generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014 by the Working Group V-MOD appointed by the International Association of Geomagnetism and Aeronomy (IAGA). It updates the previous IGRF generation with a definitive main field model for epoch 2010.0, a main field model for epoch 2015.0, and a linear annual predictive secular variation model for 2015.0-2020.0. Here, we present the equations defining the IGRF model, p...

Integrin and GPCR Crosstalk in the Regulation of ASM Contraction Signaling in Asthma.

Science.gov (United States)

Teoh, Chun Ming; Tam, John Kit Chung; Tran, Thai

2012-01-01

Airway hyperresponsiveness (AHR) is one of the cardinal features of asthma. Contraction of airway smooth muscle (ASM) cells that line the airway wall is thought to influence aspects of AHR, resulting in excessive narrowing or occlusion of the airway. ASM contraction is primarily controlled by agonists that bind G protein-coupled receptor (GPCR), which are expressed on ASM. Integrins also play a role in regulating ASM contraction signaling. As therapies for asthma are based on symptom relief, better understanding of the crosstalk between GPCRs and integrins holds good promise for the design of more effective therapies that target the underlying cellular and molecular mechanism that governs AHR. In this paper, we will review current knowledge about integrins and GPCRs in their regulation of ASM contraction signaling and discuss the emerging concept of crosstalk between the two and the implication of this crosstalk on the development of agents that target AHR.

12th International Conference on Computing and Information Technology

CERN Document Server

Boonkrong, Sirapat; Unger, Herwig

2016-01-01

This proceedings book presents recent research work and results in the area of communication and information technologies. The chapters of this book contain the main, well-selected and reviewed contributions of scientists who met at the 12th International Conference on Computing and Information Technology (IC2IT) held during 7th - 8th July 2016 in Khon Kaen, Thailand The book is divided into three parts: “User Centric Data Mining and Text Processing”, “Data Mining Algoritms and their Applications” and “Optimization of Complex Networks”.

Risk-informed technology developments for nuclear power plants within the ASME in 2000-2001

International Nuclear Information System (INIS)

Wesley Rowley, C.; Balkey, K.R.

2001-01-01

The purpose of this paper is to provide information on developments within the ASME to support risk-informing NRC regulations for nuclear power plants. This paper builds on a publication at ICONE-8 that discussed ASME risk-informed nuclear power plant initiatives, both in Research and in Codes and Standards, particularly those related to risk-informing Part 50 of the 10 CFR (Code of federal regulations). During the past year, the ASME BNCS formed a Task Force to focus the Society's efforts to support risk-informing 10 CFR Part 50. Key efforts underway that are guided by the task force include finalizing the ASME PRA (probability risk assessment) Standard, developing a Code Case to risk-inform the repair, replacement, and modification activities for ASME components, and developing a Code Case to risk-inform the safety classification of pressure boundary components. Several other initiatives are also under investigation such as introducing risk insights into other ASME nuclear codes and standards supported by appropriate research and technical basis information. Supplementary information will also be provided to update an initial high level plan of ASME risk-informed initiatives for nuclear power plants that was presented at ICONE-8, including plans to communicate these risk-informed technology developments to the public. The authors included and acknowledged contributions from several other cognizant members of the ASME BNCS (board on nuclear codes standards) Task Group on RIP50 in the paper. (authors)

PREFACE: 8th International Symposium of the Digital Earth (ISDE8)

Science.gov (United States)

2014-02-01

Proceedings of the 8th International Symposium of Digital Earth (8th ISDE) 2013 Kuching, Sarawak, Malaysia, 26th-29th August, 2013 Conference logo This proceedings consists of the peer-reviewed papers from 8th International Symposium for Digital Earth (ISDE) held in Kuching, Sarawak, Malaysia during 26th-29th August, 2013. The 8th ISDE was a successful event in the Symposium Series of the International Society of Digital Earth, that was previously held in China (1999), Canada (2001), Czech Republic (2003), Japan (2005), the United States (2007), China (2009), and Australia (2011). The 8th ISDE, with the theme 'Transforming Knowledge into Sustainable Practice' aims to enable digital earth scientists, experts and professionals related to the field of geospatial science and technology to provide a brand new opportunity to share their ideas and insights on how we share knowledge and act together globally. In addition, the ISDE symposium series has been providing a venue for researchers and industry practitioners to discuss new ideas, collaborate to solve complex solutions to various complex problems, and importantly, pave new ways in digital earth environment. This 8th ISDE included 20 technical sessions, workshops and student sessions in various areas of digital earth; ranging from digital earth vision & innovation; earth observation technologies; ICT technologies (including spatial data infrastructures); empowering the community and engaging society; applications and innovation of digital earth for environmental applications such as hazard, pollution, flood, air quality, disaster and health, biodiversity, sustainability, forestry, early warning and emergency management, national security, natural resource management and agriculture; mining, energy and resources development; transformation towards sustainable low carbon society; digital city and green cities: towards urban sustainability; and managing water environment for sustainable development. The success of the 8

Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development.

Science.gov (United States)

Zhou, Yuetao; Salker, Madhuri S; Walker, Britta; Münzer, Patrick; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Singh, Yogesh; Lang, Florian

2016-01-01

Regulatory T cell (Treg) is required for the maintenance of tolerance to various tissue antigens and to protect the host from autoimmune disorders. However, Treg may, indirectly, support cancer progression and bacterial infections. Therefore, a balance of Treg function is pivotal for adequate immune responses. Acid sphingomyelinase (ASM) is a rate limiting enzyme involved in the production of ceramide by breaking down sphingomyelin. Previous studies in T-cells have suggested that ASM is involved in CD28 signalling, T lymphocyte granule secretion, degranulation, and vesicle shedding similar to the formation of phosphatidylserine-exposing microparticles from glial cells. However, whether ASM affects the development of Treg has not yet been described. Splenocytes, isolated Naive T lymphocytes and cultured T cells were characterized for various immune T cell markers by flow cytometery. Cell proliferation was measured by Carboxyfluorescein succinimidyl ester (CFSE) dye, cell cycle analysis by Propidium Iodide (PI), mRNA transcripts by q-RT PCR and protein expression by Western Blotting respectively. ASM deficient mice have higher number of Treg compared with littermate control mice. In vitro induction of ASM deficient T cells in the presence of TGF-β and IL-2 lead to a significantly higher number of Foxp3+ induced Treg (iTreg) compared with control T-cells. Further, ASM deficient iTreg has less AKT (serine 473) phosphorylation and Rictor levels compared with control iTreg. Ceramide C6 led to significant reduction of iTreg in both ASM deficient and WT mice. The reduction in iTreg leads to induction of IL-1β, IL-6 and IL-17 but not IFN-γ mRNA levels. ASM is a negative regulator of natural and iTreg. © 2016 The Author(s) Published by S. Karger AG, Basel.

10th International ISAAC Congress

CERN Document Server

Rodino, Luigi

2016-01-01

This book collects lectures given by the plenary speakers at the 10th International ISAAC Congress, held in Macau, China in 2015. The contributions, authored by eminent specialists, present some of the most exciting recent developments in mathematical analysis, probability theory, and related applications. Topics include: partial differential equations in mathematical physics, Fourier analysis, probability and Brownian motion, numerical analysis, and reproducing kernels. The volume also presents a lecture on the visual exploration of complex functions using the domain coloring technique. Thanks to the accessible style used, readers only need a basic command of calculus.

4th International Joint Conference on Computational Intelligence

CERN Document Server

Correia, António; Rosa, Agostinho; Filipe, Joaquim

2015-01-01

The present book includes extended and revised versions of a set of selected papers from the Fourth International Joint Conference on Computational Intelligence (IJCCI 2012)., held in Barcelona, Spain, from 5 to 7 October, 2012. The conference was sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC) and was organized in cooperation with the Association for the Advancement of Artificial Intelligence (AAAI). The conference brought together researchers, engineers and practitioners in computational technologies, especially those related to the areas of fuzzy computation, evolutionary computation and neural computation. It is composed of three co-located conferences, each one specialized in one of the aforementioned -knowledge areas. Namely: - International Conference on Evolutionary Computation Theory and Applications (ECTA) - International Conference on Fuzzy Computation Theory and Applications (FCTA) - International Conference on Neural Computation Theory a...

Adoption of ASME Code Section XI for ISI to Research Reactors

International Nuclear Information System (INIS)

Tawfik, Y.E.; El-sesy, I.A.; Shaban, H.I.; Ibrahim, M.M.

2002-01-01

ETRR-2 (Second Egyptian thermal research reactor) is a multi-purpose, pool- type reactor with an open water surface and variable core arrangement. The core power is 22 MWth, cooled and moderated by light water and with beryllium reflectors. It contains plate- type fuel elements (MTR type, 19.7% enriched uranium) with aluminum clad. The ETRR-2 reactor consist of 57 systems and around 200 subsystems. These systems contain many mechanical components such as tanks, pipes, valves, pumps, heat exchangers, cooling tower, air compressors, and supports. In this present work, a trial was made to adopt the general requirements of ASME code, section XI to ETRR-2 research reactor. ASME (American Society of Mechanical Engineers) boiler and pressure vessel Code, section XI, provides requirements for in-service inspection (ISI) and in-service testing (IST) of components and systems, and repair/replacement activities in a nuclear power plant. Also, IAEA (International Atomic Energy Authority) has published some recommendations for ISI for research reactors similar to that rules and requirements specified in ASME. The complete ISI program requires several steps that have to be performed in sequence. These steps are described in many logic flow charts (LFC's). These logic flow charts include; the general LFC's for all steps required to complete ISI program, the LFC's for examination requirements, the LFC's for flaw evaluation modules, and the LFC's for acceptability of welds for class 1 components. This program includes, also, the inspection program for welded parts of the reactor components during its lifetime. This inspection program is applied for each system and subsystem of ETRR-2 reactor. It includes the examination area type, the component type, the part to be examined, the weld type, the examination method, the inspection program schedule, and the detailed figures of the welded components. (authors)

ASM-024, a piperazinium compound, promotes the in vitro relaxation of β2-adrenoreceptor desensitized tracheas.

Science.gov (United States)

Israël-Assayag, Evelyne; Beaulieu, Marie-Josée; Cormier, Yvon

2015-01-01

Inhaled β2-adrenoreceptor agonists are widely used in asthma and chronic obstructive pulmonary disease (COPD) for bronchoconstriction relief. β2-Adrenoreceptor agonists relax airway smooth muscle cells via cyclic adenosine monophosphate (cAMP) mediated pathways. However, prolonged stimulation induces functional desensitization of the β2-adrenoreceptors (β2-AR), potentially leading to reduced clinical efficacy with chronic or prolonged administration. ASM-024, a small synthetic molecule in clinical stage development, has shown activity at the level of nicotinic receptors and possibly at the muscarinic level and presents anti-inflammatory and bronchodilator properties. Aerosolized ASM-024 reduces airway resistance in mice and promotes in-vitro relaxation of tracheal and bronchial preparations from animal and human tissues. ASM-024 increased in vitro relaxation response to maximally effective concentration of short-acting beta-2 agonists in dog and human bronchi. Although the precise mechanisms by which ASM-024 promotes airway smooth muscle (ASM) relaxation remain unclear, we hypothesized that ASM-024 will attenuate and/or abrogate agonist-induced contraction and remain effective despite β2-AR tachyphylaxis. β2-AR tachyphylaxis was induced with salbutamol, salmeterol and formoterol on guinea pig tracheas. The addition of ASM-024 relaxed concentration-dependently intact or β2-AR desensitized tracheal rings precontracted with methacholine. ASM-024 did not induce any elevation of intracellular cAMP in isolated smooth muscle cells; moreover, blockade of the cAMP pathway with an adenylate cyclase inhibitor had no significant effect on ASM-024-induced guinea pig trachea relaxation. Collectively, these findings show that ASM-024 elicits relaxation of β2-AR desensitized tracheal preparations and suggest that ASM-024 mediates smooth muscle relaxation through a different target and signaling pathway than β2-adrenergic receptor agonists. These findings suggest ASM-024

7th International Meshing Roundtable '98

Energy Technology Data Exchange (ETDEWEB)

Eldred, T.J.

1998-10-01

The goal of the 7th International Meshing Roundtable is to bring together researchers and developers from industry, academia, and government labs in a stimulating, open environment for the exchange of technical information related to the meshing process. In the past, the Roundtable has enjoyed significant participation from each of these groups from a wide variety of countries.

Analysis of preservice inspection relief requests and recommendations for ASME code changes

International Nuclear Information System (INIS)

Cook, J.F.

1985-05-01

NRC regulations require that preservice inspection (PSI) of nuclear plants be performed in accordance with referenced editions and addenda of Division 1 rules of Section XI, ''Rules for Inservice Inspection of Nuclear Power Plant Components'', of the ASME Boiler and Pressure Vessel Code (ASME Code). The regulations permit applicants to request and obtain relief from the NRC from specific ASME Code requirements that are determined to be impractical. Applicant requests for relief from preservice inspection (PSI) requirements were compiled and analyzed. From this data, covering a total of 178 relief requests, common problems with examination requirements were identified. Changes to examination requirements to solve selected problems are proposed. By following later ASME Code requirements, 46 out of the 178 relief requests can be eliminated. Implementing proposed Code changes would eliminate another 25 relief requests, leaving 107 relief requests out of the original 178 relief requests covered by this survey

Determination of Sc and Th in ScI3-NaI-ThI4 sample

International Nuclear Information System (INIS)

Yuan Hui; Yang Zhihong

1999-01-01

Determination of Sc and Th in ScI 3 -NaI-ThI 4 sample is studied by X-ray fluorescence and complexometry. The effect of working condition of Sc on X-ray fluorescence spectrometer and different sample-making method on the determination of Sc and Th are studied experimentally. The X-ray fluorescence analysis of determination of Sc and Th is developed by polyester film sample-making technique, the measuring precision of Sc and Th is better than 4%. The effect of acidity and temperature on the determining end point of titration is obvious. The results of different complexometric methods are compared. The precision of Sc and Th is less than 2% by comlexometry, it is fit for the routine analysis of ScI 3 -NaI-ThI 4 sample

6th International Symposium on Ambient Intelligence

CERN Document Server

Novais, Paulo; Pereira, António; González, Gabriel; Fernández-Caballero, Antonio

2015-01-01

This volume contains the proceedings of the 6th International Symposium on Ambient Intelligence (ISAmI 2015), held in Salamanca, Spain on June 3th-5th at the University of Salamanca. After a careful review, 27 papers from 10 different countries were selected to be presented in ISAmI 2015 at the conference and published in the proceedings.  ISAmI has been running annually and aiming to bring together researchers from various disciplines that constitute the scientific field of Ambient Intelligence to present and discuss the latest results, new ideas, projects and lessons learned, namely in terms of software and applications, and aims to bring together researchers from various disciplines that are interested in all aspects of this area. Ambient Intelligence is a recent paradigm emerging from Artificial Intelligence, where computers are used as proactive tools assisting people with their day-to-day activities, making everyone’s life more comfortable. Another main concern of AmI originates from the human comput...

The 4th international colloquium on process simulation. Proceedings

Energy Technology Data Exchange (ETDEWEB)

Jokilaakso, A [Helsinki Univ. of Technology, Otaniemi (Finland). Dept. of Materials Science and Metallurgy

1998-12-31

The papers collected in this volume were presented at the 4th Colloquium on Process Simulation held at Helsinki University of Technology, Espoo, Finland, June 11-13, 1997. In the more developed industrial nations, the processes for producing chemicals, energy, and materials encounter environmental concern and laws which challenge engineers to develop the processes towards more efficient, economical and safe operation. This necessitates more thorough understanding of the processes and phenomena involved. Formerly, the development of the processes was largely based on trial and error, whereas today, the development of computer performance together with the diversification of modelling software enables simulation of the processes. The increased capacity and possibilities for modelling the processes brought by the improved hardware and software, have generated a strong demand for more accurate mathematical descriptions of the processes. Especially, the coupling of computational fluid dynamics and chemical kinetics, combustion, and thermodynamics is of current interest in process oriented technology. This colloquium attempts to give examples of modelling efforts in operation in different universities, research institutes and companies. Furthermore, the aim of this colloquium is to offer an annual opportunity to the researchers to come together and discuss their common problems and the state of their investigations

The 4th international colloquium on process simulation. Proceedings

Energy Technology Data Exchange (ETDEWEB)

Jokilaakso, A. [Helsinki Univ. of Technology, Otaniemi (Finland). Dept. of Materials Science and Metallurgy

1997-12-31

The papers collected in this volume were presented at the 4th Colloquium on Process Simulation held at Helsinki University of Technology, Espoo, Finland, June 11-13, 1997. In the more developed industrial nations, the processes for producing chemicals, energy, and materials encounter environmental concern and laws which challenge engineers to develop the processes towards more efficient, economical and safe operation. This necessitates more thorough understanding of the processes and phenomena involved. Formerly, the development of the processes was largely based on trial and error, whereas today, the development of computer performance together with the diversification of modelling software enables simulation of the processes. The increased capacity and possibilities for modelling the processes brought by the improved hardware and software, have generated a strong demand for more accurate mathematical descriptions of the processes. Especially, the coupling of computational fluid dynamics and chemical kinetics, combustion, and thermodynamics is of current interest in process oriented technology. This colloquium attempts to give examples of modelling efforts in operation in different universities, research institutes and companies. Furthermore, the aim of this colloquium is to offer an annual opportunity to the researchers to come together and discuss their common problems and the state of their investigations

Evaluation of practicality of ASME code, Section XI

International Nuclear Information System (INIS)

Mattu, R.K.; Lauderdale, J.R.; Liu, S.N.; Lance, J.J.

2004-01-01

Many nuclear power plants have found that it is impractical or unduly burdensome to comply with some ASME Boiler and Pressure Code provisions and have sought relief from those provisions from the Nuclear Regulatory Commission. An Electric Power Research Institute (EPRI) project is evaluating such Code provisions and alternatives to them that will meet the safety intent of the Code with less burden on utilities. The methodology is to extract data from an on-line data base of relief requests since 1980, analyse the data to identify burdensome provisions for which there are satisfactory alternatives, and recommend changes in the Code to the ASME. (author)

CXCL1 is a negative regulator of mast cell chemotaxis to airway smooth muscle cell products in vitro.

Science.gov (United States)

Alkhouri, H; Moir, L M; Armour, C L; Hughes, J M

2014-03-01

Activated mast cells (MC) numbers on airway smooth muscle (ASM) are increased in eosinophilic asthma. In vitro, asthmatic cytokine-stimulated ASM cell-conditioned medium (CM) induces more MC chemotaxis than CM from nonasthmatic ASM cells. Intriguingly the nonasthmatic ASM CM inhibits MC chemotaxis to the asthmatic ASM CM. However, the inhibitory factor(s) in the nonasthmatic ASM CM is still to be identified. To identify the factor(s) released by nonasthmatic ASM cells that inhibits MC chemotaxis. Confluent, serum-starved ASM cells from donors with and without asthma were stimulated with IL-1β and T-helper (Th)1 (TNFα and IFNγ) or Th2 (IL-4, IL-13) cytokines, or left unstimulated. CM samples were collected after 24 h, and a potential inhibitory factor identified using cytokine protein arrays. Its production was assessed using ELISA and RT-PCR and inhibitory role investigated in MC chemotaxis and Ca(2+) mobilization assays. Only CXCL1 was produced in greater amounts by nonasthmatic than asthmatic ASM cells following Th1 and Th2 cytokine stimulation. CXCL1 mRNA expression was also increased. Exogenous rh-CXCL1 significantly inhibited MC intracellular Ca(2+) mobilization and chemotaxis to either CXCL10, CXCL8 or CM collected from asthmatic ASM cells following Th1 or Th2 cytokine stimulation. Neutralizing CXCL1 in nonasthmatic ASM CM or blocking its receptor significantly promoted MC chemotaxis. CXCL1 was a major factor regulating MC chemotaxis in vitro. Its differential release by ASM cells may explain the differences observed in MC localization to the ASM of people with and without asthma. CXCL1 inhibition of MC recruitment to the ASM may lead to new targets to limit asthma pathophysiology. © 2013 John Wiley & Sons Ltd.

Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma.

Science.gov (United States)

Boulet, Louis-Philippe; Gauvreau, Gail M; Cockcroft, Donald W; Davis, Beth; Vachon, Luc; Cormier, Yvon; O'Byrne, Paul M

2015-01-01

To evaluate the safety, tolerability and clinical activity of ASM-024, a new cholinergic compound with dual nicotinic and muscarinic activity, in mild allergic asthma. The present study involved 24 stable, mild allergic asthmatic subjects. In a cross-over design, ASM-024 (50 mg or 200 mg) or placebo were administered once daily by nebulization over three periods of nine consecutive days separated by a three-week washout. The effect of each treatment on the forced expiratory volume in 1 s (FEV1), provocative concentration of methacholine causing a 20% decline in FEV1 (PC20), early and late asthmatic responses, and allergen-induced inflammation were measured. Seventeen subjects completed the study. During treatment with ASM-024 at 50 mg or 200 mg, the PC20 value increased respectively from a mean (± SD) 2.56±3.86 mg/mL to 4.11 mg/mL (P=0.007), and from 3.12±4.37 mg/mL to 5.23 mg/mL (P=0.005) (no change with placebo). On day 7 (day preceding allergen challenge), postdosing FEV1 increased by 2.0% with 50 mg (P=0.005) and 1.9% with 200 mg (P=0.008) (placebo -1.1%). ASM-24 had no inhibitory effect on early and late asthmatic responses, nor on sputum eosinophil or neutrophil levels. ASM-024 induced no serious adverse events, but caused cough in 22% and 48% of the subjects with 50 mg and 200 mg, respectively, compared with 10% who were on placebo. ASM-024 did not inhibit allergen-induced asthmatic response and related airway inflammation, but reduced methacholine airway responsiveness and slightly improved lung function. The mechanism by which ASM-024 improves these outcomes requires further study.

50th IMO - 50 Years of International Mathematical Olympiads

CERN Document Server

Gronau, Hans-Dietrich; Schleicher, Dierk

2011-01-01

In July 2009 Germany hosted the 50th International Mathematical Olympiad (IMO). For the very first time the number of participating countries exceeded 100, with 104 countries from all continents. Celebrating the 50th anniversary of the IMO provides an ideal opportunity to look back over the past five decades and to review its development to become a worldwide event. This book is a report about the 50th IMO as well as the IMO history. A lot of data about all the 50 IMOs are included. We list the most successful contestants, the results of the 50 Olympiads and the 112 countries that have ever ta

High Level Analysis, Design and Validation of Distributed Mobile Systems with CoreASM

Science.gov (United States)

Farahbod, R.; Glässer, U.; Jackson, P. J.; Vajihollahi, M.

System design is a creative activity calling for abstract models that facilitate reasoning about the key system attributes (desired requirements and resulting properties) so as to ensure these attributes are properly established prior to actually building a system. We explore here the practical side of using the abstract state machine (ASM) formalism in combination with the CoreASM open source tool environment for high-level design and experimental validation of complex distributed systems. Emphasizing the early phases of the design process, a guiding principle is to support freedom of experimentation by minimizing the need for encoding. CoreASM has been developed and tested building on a broad scope of applications, spanning computational criminology, maritime surveillance and situation analysis. We critically reexamine here the CoreASM project in light of three different application scenarios.

Estimates of margins in ASME Code strength values for stainless steel nuclear piping

International Nuclear Information System (INIS)

Ware, A.G.

1995-01-01

The margins in the ASME Code stainless steel allowable stress values that can be attributed to the variations in material strength are evaluated for nuclear piping steels. Best-fit curves were calculated for the material test data that were used to determine allowable stress values for stainless steels in the ASME Code, supplemented by more recent data, to estimate the mean stresses. The mean yield stresses (on which the stainless steel S m values are based) from the test data are about 15 to 20% greater than the ASME Code yield stress values. The ASME Code yield stress values are estimated to approximately coincide with the 97% confidence limit from the test data. The mean and 97% confidence limit values can be used in the probabilistic risk assessments of nuclear piping

The 17th International Conference on Biomedical Engineering

CERN Document Server

Lim, Chwee; Leo, Hwa

2017-01-01

This volume presents the proceedings of the 16th ICMBE held from 4th to 7th December 2016, Singapore. Topics of the proceedings include 6 tracks: BioImaging and BioSignals, Bio-Micro/Nano Technologies BioRobotics and Medical Devices, Biomaterials and Regenerative Medicine.- BioMechanics and Mechanobiology., Engineering/Synthetic Biology.

8th International Symposium on Heating, Ventilation and Air Conditioning

CERN Document Server

Zhu, Yingxin; Li, Yuguo; Vol.1 Indoor and Outdoor Environment; Vol.2 HVAC&R Component and Energy System; Vol.3 Building Simulation and Information Management

2014-01-01

Proceedings of the 8th International Symposium on Heating, Ventilation and Air Conditioning is based on the 8th International Symposium of the same name (ISHVAC2013), which took place in Xi’an on October 19-21, 2013. The conference series was initiated at Tsinghua University in 1991 and has since become the premier international HVAC conference initiated in China, playing a significant part in the development of HVAC and indoor environmental research and industry around the world. This international conference provided an exclusive opportunity for policy-makers, designers, researchers, engineers and managers to share their experience. Considering the recent attention on building energy consumption and indoor environments, ISHVAC2013 provided a global platform for discussing recent research on and developments in different aspects of HVAC systems and components, with a focus on building energy consumption, energy efficiency and indoor environments. These categories span a broad range of topics, and the proce...

A minimal path searching approach for active shape model (ASM)-based segmentation of the lung

Science.gov (United States)

Guo, Shengwen; Fei, Baowei

2009-02-01

We are developing a minimal path searching method for active shape model (ASM)-based segmentation for detection of lung boundaries on digital radiographs. With the conventional ASM method, the position and shape parameters of the model points are iteratively refined and the target points are updated by the least Mahalanobis distance criterion. We propose an improved searching strategy that extends the searching points in a fan-shape region instead of along the normal direction. A minimal path (MP) deformable model is applied to drive the searching procedure. A statistical shape prior model is incorporated into the segmentation. In order to keep the smoothness of the shape, a smooth constraint is employed to the deformable model. To quantitatively assess the ASM-MP segmentation, we compare the automatic segmentation with manual segmentation for 72 lung digitized radiographs. The distance error between the ASM-MP and manual segmentation is 1.75 +/- 0.33 pixels, while the error is 1.99 +/- 0.45 pixels for the ASM. Our results demonstrate that our ASM-MP method can accurately segment the lung on digital radiographs.

A Minimal Path Searching Approach for Active Shape Model (ASM)-based Segmentation of the Lung.

Science.gov (United States)

Guo, Shengwen; Fei, Baowei

2009-03-27

We are developing a minimal path searching method for active shape model (ASM)-based segmentation for detection of lung boundaries on digital radiographs. With the conventional ASM method, the position and shape parameters of the model points are iteratively refined and the target points are updated by the least Mahalanobis distance criterion. We propose an improved searching strategy that extends the searching points in a fan-shape region instead of along the normal direction. A minimal path (MP) deformable model is applied to drive the searching procedure. A statistical shape prior model is incorporated into the segmentation. In order to keep the smoothness of the shape, a smooth constraint is employed to the deformable model. To quantitatively assess the ASM-MP segmentation, we compare the automatic segmentation with manual segmentation for 72 lung digitized radiographs. The distance error between the ASM-MP and manual segmentation is 1.75 ± 0.33 pixels, while the error is 1.99 ± 0.45 pixels for the ASM. Our results demonstrate that our ASM-MP method can accurately segment the lung on digital radiographs.

The 25th anniversary of the International Atomic Energy Agency

International Nuclear Information System (INIS)

Osztrovszki, Gy.

1982-01-01

The leader of the Hungarian delegation at the 26th General Assembly of the International Atomic Energy (IAEA) held in Vienna in September, 1982, on the occasion of the IAEA's 25th anniversary, presented a short review of the IAEA's activities during its existence, the Hungarian participation in them and Hungary's efforts in the peaceful uses of the nuclear energy. (A.L.)

Proceedings of the Third International Workshop on Jointed Structures.

Energy Technology Data Exchange (ETDEWEB)

Starr, Michael James; Brake, Matthew Robert; Segalman, Daniel Joseph; Bergman, Lawrence A.; Ewins, David J.

2013-08-01

The Third International Workshop on Jointed Structures was held from August 16th to 17th, 2012, in Chicago Illinois, following the ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Thirty two researchers from both the United States and international locations convened to discuss the recent progress of mechanical joints related research and associated efforts in addition to developing a roadmap for the challenges to be addressed over the next five to ten years. These proceedings from the workshop include the minutes of the discussions and follow up from the 2009 workshop [1], presentations, and outcomes of the workshop. Specifically, twelve challenges were formulated from the discussions at the workshop, which focus on developing a better understanding of uncertainty and variability in jointed structures, incorporating high fidelity models of joints in simulations that are tractable/efficient, motivating a new generation of researchers and funding agents as to the importance of joint mechanics research, and developing new insights into the physical phenomena that give rise to energy dissipation in jointed structures. The ultimate goal of these research efforts is to develop a predictive model of joint mechanics.

Review of ASME nuclear codes and standards- subcommittee on repairs, replacements, and modifications

International Nuclear Information System (INIS)

Mawson, T.J.

1990-01-01

As requested by the ASME board on Nuclear Codes and Standards, the Pressure Vessel Research Committee initiated a project to review Sections III and XI of the ASME Boiler and Pressure Vessel Code for the purposes of improving, clarifying, providing transition, consistency, compatibility, and simplifying code requirements. The project was organized with six subcommittees to address various Code activities: design; tests and examinations; documentation; quality assurance; repair, replacement and modification; and general requirements. This paper discusses how the subcommittee on repair, replacement and modification was organized to review the repair, replacement and modification requirements of the ASME boiler and pressure vessel code, Section III and Section XI for Class 1, 2, and 3 and MC components and their supports, and other documents of the nuclear industry related to the repair, replacement and modification requirements of the ASME code

17th International Conference on Petroleum Phase Behavior and Fouling

DEFF Research Database (Denmark)

von Solms, Nicolas; Yan, Wei; Andersen, Simon

2017-01-01

This special section of Energy & Fuels contains contributedpapers from the 17th International Conference on PetroleumPhase Behavior and Fouling (Petrophase 2016). Petrophase 2016 was organized by the Technical University of Denmark and Schlumberger and took place in Elsinore (Helsingør) Denmark...... from June 19th to 23rd at the Beach Hotel Marienlyst. Petrophase is an international conference aimed at researchers in industry and academia dedicated to the study of the properties and chemistry of petroleum fluids and their effect on producing, processing, and refining in the upstream, midstream......, and downstream industries. The conference started in 1999 as “The International Conference on Petroleum Phase Behavior & Fouling” and has since evolved into an annual event taking place in countries all around the world. Petrophase has been fortunate to have enjoyed financial and organizational support from many...

Creep-Fatigue Damage Evaluation of a Model Reactor Vessel and Reactor Internals of Sodium Test Facility according to ASME-NH and RCC-MRx Codes

International Nuclear Information System (INIS)

Lim, Dong-Won; Lee, Hyeong-Yeon; Eoh, Jae-Hyuk; Son, Seok-Kwon; Kim, Jong-Bum; Jeong, Ji-Young

2016-01-01

The objective of the STELLA-2 is to support the specific design approval for PGSFR by synthetic reviews of key safety issues and code validations through the integral effect tests. Due to its high temperature operation in SFRs (and in a testing facility) up to 550 °C, thermally induced creep-fatigue damage is very likely in components including a reactor vessel, reactor internals (interior structures), heat exchangers, pipelines, etc. In this study, structural integrity of the components such as reactor vessel and internals in STELLA-2 has been evaluated against creep-fatigue failures at a concept-design step. As 2D analysis yields far conservative results, a realistic 3D simulation is performed by a commercial software. A design integrity guarding against a creep-fatigue damage failure operating at high temperature was evaluated for the reactor vessel with its internal structure of the STELLA-2. Both the high temperature design codes were used for the evaluation, and results were compared. All the results showed the vessel as a whole is safely designed at the given operating conditions, while the ASME-NH gives a conservative evaluation

Creep-Fatigue Damage Evaluation of a Model Reactor Vessel and Reactor Internals of Sodium Test Facility according to ASME-NH and RCC-MRx Codes

Energy Technology Data Exchange (ETDEWEB)

Lim, Dong-Won; Lee, Hyeong-Yeon; Eoh, Jae-Hyuk; Son, Seok-Kwon; Kim, Jong-Bum; Jeong, Ji-Young [KAERI, Daejeon (Korea, Republic of)

2016-05-15

The objective of the STELLA-2 is to support the specific design approval for PGSFR by synthetic reviews of key safety issues and code validations through the integral effect tests. Due to its high temperature operation in SFRs (and in a testing facility) up to 550 °C, thermally induced creep-fatigue damage is very likely in components including a reactor vessel, reactor internals (interior structures), heat exchangers, pipelines, etc. In this study, structural integrity of the components such as reactor vessel and internals in STELLA-2 has been evaluated against creep-fatigue failures at a concept-design step. As 2D analysis yields far conservative results, a realistic 3D simulation is performed by a commercial software. A design integrity guarding against a creep-fatigue damage failure operating at high temperature was evaluated for the reactor vessel with its internal structure of the STELLA-2. Both the high temperature design codes were used for the evaluation, and results were compared. All the results showed the vessel as a whole is safely designed at the given operating conditions, while the ASME-NH gives a conservative evaluation.

Proceedings of the 18th International Conference on Engineering Design

DEFF Research Database (Denmark)

The 18th International Conference on Engineering Design, ICED11, was held August 15-18th 2011 at The Technical University of Denmark (DTU), Copenhagen. The Conference is the flagship event of the Design Society, a society dedicated to contributing to a broad and established understanding of devel......The 18th International Conference on Engineering Design, ICED11, was held August 15-18th 2011 at The Technical University of Denmark (DTU), Copenhagen. The Conference is the flagship event of the Design Society, a society dedicated to contributing to a broad and established understanding...... of development and design. The ICED series of conferences has a long tradition, which started in 1981 with the first ICED in Rome. A total of 419 papers were presented at ICED11, each double-blind reviewed by multiple reviewers. The papers included research papers and case studies on a variety of topics...... concerned with design thinking, theory, and practice, with a premium placed on evidence-based research. The papers are published in a total of ten volumes of Proceedings, in addition to electronic publication. This volume is the first of two concerned with Design Methods and Tools, and contains 45 papers...

[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.

Science.gov (United States)

Sweeney, David; Hollins, Fay; Gomez, Edith; Saunders, Ruth; Challiss, R A John; Brightling, Christopher E

2014-07-01

The cause of airway smooth muscle (ASM) hypercontractility in asthma is not fully understood. The relationship of spontaneous intracellular calcium oscillation frequency in ASM to asthma severity was investigated. Oscillations were increased in subjects with impaired lung function abolished by extracellular calcium removal, attenuated by caffeine and unaffected by verapamil or nitrendipine. Whether modulation of increased spontaneous intracellular calcium oscillations in ASM from patients with impaired lung function represents a therapeutic target warrants further investigation. © 2014 The Authors. Respirology published by Wiley Publishing Asia Pty Ltd on behalf of Asian Pacific Society of Respirology.

On possibility of degradation of lava-like fuel-containing materials of the 4-th block of Chernobyl NPP under internal self-irradiation by alpha-particle sources

International Nuclear Information System (INIS)

Pazukhin, Eh. M.; Borovoj, A.A.; Rudya, K.G.

2002-01-01

It is shown that internal self-irradiation by alpha-particle beam cannot be a cause of change of strength characteristics of silicate matrix and so a cause of degradation of Chernobyl lava-like materials. A new method is proposed for management with lava-like fuel-containing materials of the 4-th block: vitrification in smelter unit situated in bubbler-basin and storage of prepared immobilized compacts in corresponding depositories [ru

The 4th Thermodynamic Principle?

International Nuclear Information System (INIS)

Montero Garcia, Jose de la Luz; Novoa Blanco, Jesus Francisco

2007-01-01

It should be emphasized that the 4th Principle above formulated is a thermodynamic principle and, at the same time, is mechanical-quantum and relativist, as it should inevitably be and its absence has been one of main the theoretical limitations of the physical theory until today.We show that the theoretical discovery of Dimensional Primitive Octet of Matter, the 4th Thermodynamic Principle, the Quantum Hexet of Matter, the Global Hexagonal Subsystem of Fundamental Constants of Energy and the Measurement or Connected Global Scale or Universal Existential Interval of the Matter is that it is possible to be arrived at a global formulation of the four 'forces' or fundamental interactions of nature. The Einstein's golden dream is possible

Investigating ASME allowable loads with finite element analyses

International Nuclear Information System (INIS)

Mattar Neto, Miguel; Bezerra, Luciano M.; Miranda, Carlos A. de J.; Cruz, Julio R.B.

1995-01-01

The evaluation of nuclear components using finite element analysis (FEA) does not generally fall into the shell type verification adopted by the ASME Code. Consequently, the demonstration that the modes of failure are avoided sometimes is not straightforward. Allowable limits, developed by limit load theory, require the computation of shell membrane and bending stresses. How to calculate these stresses from FEA is not necessarily self-evident. One approach to be considered is to develop recommendations in a case-by-case basis for the most common pressure vessel geometries and loads based on comparison between the results of elastic and plastic FEA. In this paper, FE analyses of common 2D and complex 3D geometries are examined and discussed. It will be clear that in the cases studied, stress separation and categorization are not self-evident and simple tasks to undertake. Certain unclear recommendations of ASME Code can lead the stress analyst to non conservative designs as will be demonstrated in this paper. At the endo of this paper, taking into account comparison between elastic and elastic-plastic FE results from ANSYS some observations, suggestions and conclusions about the degree of conservatism of the ASME recommendations will be addressed. (author)

25th Annual International Laser Physics Workshop (LPHYS’16)

International Nuclear Information System (INIS)

2017-01-01

EDITORIALDear Readers,The 25th annual International Laser Physics Workshop, LPHYS’16, took place in the city of Yerevan, Republic of Armenia. 319 participants from 32 countries attended the conference. It was hosted by the Yerevan Physics Institute, A Alikhanyan National Laboratory. This year the conference has been endorsed by the Optical Society (OSA), the year the society celebrates its 100th anniversary.The LPHYS’16 Steering Committee and the Advisory and Program Committee would like to extend their sincere gratitude to Dr. Koryun B Oganesyan (Chair of the Local Organizing Committee) and to his team for the outstanding job performed on organizing, arranging, managing and putting in order the conference. Their combined effort lead to a successful result.In this volume of the IOP Journal of Physics: Conference Series you will find selected proceedings of the Workshop in Yerevan.Please make a note that the 26th annual International Laser Physics Workshop (LPHYS’17) will take place from July 17 to July 21, 2017 in the city of Kazan, Russia hosted by the Kazan E K Zavoisky Physical-Technical Institute (KPhTI).With kind regards,Steering and Advisory and Program committeesLPHYS’16 (paper)

77 FR 76411 - Security Zone; 25th Annual North American International Auto Show, Detroit River, Detroit, MI

Science.gov (United States)

2012-12-28

...-AA87 Security Zone; 25th Annual North American International Auto Show, Detroit River, Detroit, MI..., visitors, and public officials at the 25th Annual North American International Auto Show (NAIAS), which is... Purpose The 25th Annual North American International Auto Show (NAIAS) will be held at Cobo Hall in...

77 FR 2453 - Security Zone; 24th Annual North American International Auto Show, Detroit River, Detroit, MI

Science.gov (United States)

2012-01-18

...-AA87 Security Zone; 24th Annual North American International Auto Show, Detroit River, Detroit, MI..., visitors, and public officials at the 24th Annual North American International Auto Show (NAIAS), which is... The 24th Annual North American International Auto Show (NAIAS) will be held at Cobo Hall in downtown...

Efecto de budesonida sobre la densidad y el metabolismo óseo en niños asmáticos

Directory of Open Access Journals (Sweden)

Paoli de Valeri Mariela

2000-01-01

Full Text Available OBJETIVO: Determinar el efecto de la administración de budesonida inhalado sobre la densidad, el contenido mineral y el metabolismo óseo en niños asmáticos. MATERIAL Y MÉTODOS: Estudio transversal realizado de septiembre de 1996 a julio de 1997, en el que se estudiaron 38 niños y niñas de entre 6 y 11 años de edad, seleccionados de la consulta externa de neumonología infantil del Instituto Autónomo Hospital Universitario de Los Andes, Mérida, Venezuela. Se constituyeron tres grupos: nueve niños asmáticos tratados con budesonida inhalado (300 µg/día en promedio durante más de seis meses, (grupo A, 14 niños asmáticos que no recibieron tratamiento esteroideo (grupo B y 15 niños no asmáticos (grupo C. A todos se les practicó una evaluación ósea con marcadores de formación y resorción y con una medición de la densidad (DMO y el contenido mineral óseo (CMO. Se calcularon medidas de tendencia central y de dispersión, se realizó análisis de varianza, y se utilizaron las pruebas de Fisher y Scheffé para comparación de medias. RESULTADOS: En los grupos estudiados (A, B y C los niveles séricos de calcio fueron 9.1±0.3; 9.6±0.4; 9.3±0.6 mg/ml; los de osteocalcina fueron 14.8±4.6; 13.0±2.5; 11.9±3.4 ng/dl; los de telopéptido carboxiterminal del colágeno tipo I (ICTP fueron 19.6±16.5; 14.2±15.4; 13.0±18.3 µg/l; la DMO fue de 0.67±0.06; 0.68±0.06; 0.69±0.06 g/cm², y el CMO fue de 1 158.8±217.4; 1 106.4±256.1; 1 176.5±240.5 g, respectivamente. No hubo diferencias significativas entre los grupos. CONCLUSIONES: La administración de budesonida inhalada en dosis de 100 a 400 µg/día por un periodo de seis meses no produce modificaciones en la densidad y en el metabolismo óseo en niños asmáticos.

ASME section XI: rules for inservice inspection of nuclear power plants -an introspection

Energy Technology Data Exchange (ETDEWEB)

John, P K; Anto, Y; Mungikar, C P; Wagh, P M [Nuclear Power Corporation of India Ltd., Tarapur (India). Tarapur Atomic Power Station

1994-12-31

Section XI of the ASME BPV code is addressed to the examination, test and inspection requirements of the components of nuclear power plants (NPPs). Since its inception in 1970, this code section has undergone vast changes -probably the most among other ASME BPV code sections. Section XI is full fledged and lays down requirements with regard to all preservice inspections, inservice inspection, repair and replacement of components, tests of system etc. Tarapur Atomic Power Station (TAPS) has the distinction of being one of the earliest BWR type NPPs in the world that has an inservice inspection programme organised in line with the ASME section XI requirements. This paper summarises the experiences gained from time to time using this code section and a few suggestions to prospective users. An effort is also made to explain the philosophy of inservice inspection from ASME section XI point of view. 3 refs.

ASME section XI: rules for inservice inspection of nuclear power plants -an introspection

International Nuclear Information System (INIS)

John, P.K.; Anto, Y.; Mungikar, C.P.; Wagh, P.M.

1994-01-01

Section XI of the ASME BPV code is addressed to the examination, test and inspection requirements of the components of nuclear power plants (NPPs). Since its inception in 1970, this code section has undergone vast changes -probably the most among other ASME BPV code sections. Section XI is full fledged and lays down requirements with regard to all preservice inspections, inservice inspection, repair and replacement of components, tests of system etc. Tarapur Atomic Power Station (TAPS) has the distinction of being one of the earliest BWR type NPPs in the world that has an inservice inspection programme organised in line with the ASME section XI requirements. This paper summarises the experiences gained from time to time using this code section and a few suggestions to prospective users. An effort is also made to explain the philosophy of inservice inspection from ASME section XI point of view. 3 refs

4th Conference on Microactuators and Micromechanisms

CERN Document Server

Corves, Burkhard; Jensen, Brian; Lovasz, Erwin-Christian

2017-01-01

This book brings together investigations which combine theoretical and experimental results related to such systems as capsule micromechanisms, active micro catheters, nanotube vascular stents, mechanisms for micromilling, different compliant mechanisms including grippers and compliant systems with actuators and sensors, microrobots based on vibrations, tactile sensors, tooth brackets, compliant valves, and space reflectors. This volume contains twenty-two contributions from researchers from ten countries, represented at the 4th Conference on Microactuators and Micromechanisms, which was held in 2016 in Ilmenau, Germany. The aim of the conference was to provide a special opportunity for a know-how exchange and collaboration in various disciplines concerning systems pertaining to micro-technology. This Conference was organized under the patronage of IFToMM (International Federation for the Promotion of Mechanism and Machine Science). .

Technical requirements for the ASME PRA standard for nuclear power plant applications

International Nuclear Information System (INIS)

Fleming, Karl N.; Bernsen, Sidney A.; Simard, Ronald L.

2000-01-01

In 1998 the American Society of Mechanical Engineers (ASME) formed the Committee on Nuclear Risk Management (CNRM) and a Project Team to develop a standard on PRAs for use in risk informed applications. This ASME standard is being developed to help provide an adequate level of quality in PRAs that are being used to support ASME initiatives to risk informed in-service inspection (ISI) and in-service testing (IST) of nuclear power plant components. A related need supported by the industry and the U.S. Nuclear Regulatory Commission is to reduce the level of effort that is being expended in pilot applications of risk informed initiatives to address questions about the sufficiency of quality in the supporting PRA models. The purpose of this paper is to discuss the authors' views on some of the technical issues that were encountered in the effort to develop the ASME PRA standard. Draft 12 of this standard has been issued for comment, and is currently being finalized with the aim of releasing the standard in early 2001. (author)

International School of Subnuclear Physics 50th Course

CERN Document Server

What we would like LHC to give us; ISSP 2012

2014-01-01

This book is the proceedings of the International School of Subnuclear Physics, ISSP 2012, 50th Course — ERICE, 23 June 2013 — 2 July 2012. This course was devoted to the celebrations of the 50th Anniversary of the Subnuclear Physics School which was started in 1961 by Antonino Zichichi with John Bell at CERN and formally established in 1962 by Bell, Blackett, Weisskopf, Rabi and Zichichi in Geneva (CERN). The lectures covered the latest and most significant achievements in theoretical and in experimental subnuclear physics. Readership: Directed to experts and advanced-level students in the field of Theoretical and Experimental Subnuclear Physics.

The 9th international conference on computing and information technology

CERN Document Server

Unger, Herwig; Boonkrong, Sirapat; IC2IT2013

2013-01-01

This volume contains the papers of the 9th International Conference on Computing and Information Technology (IC2IT 2013) held at King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok, Thailand, on May 9th-10th, 2013. Traditionally, the conference is organized in conjunction with the National Conference on Computing and Information Technology, one of the leading Thai national events in the area of Computer Science and Engineering. The conference as well as this volume is structured into 3 main tracks on Data Networks/Communication, Data Mining/Machine Learning, and Human Interfaces/Image processing.  

12th international conference on human retrovirology: HTLV and related retroviruses

Directory of Open Access Journals (Sweden)

Lairmore Michael D

2005-10-01

Full Text Available Abstract The 12th International Conference on Human Retrovirology: HTLV and Related Retroviruses, was held at the Half Moon Hotel in Montego Bay, Jamaica, from June 22nd to June 25th 2005. The scientific conference, sponsored by the International Retrovirology Association, is held biennially at rotating international venues around the world. The meeting brings together basic scientists, epidemiologists and clinical researchers to discuss findings to prevent HTLV infection or develop new therapies against HTLV-mediated diseases. The Association fosters the education and training of young scientists to bring new approaches to the complex problems of HTLV research, such as translational research to bring findings from the laboratory into clinical trials that benefit HTLV-infected patients. The breadth and quality of research presentations and workshops at the 12th International Conference indicate that these goals are being accomplished. As HTLV research enters its third decade a new generation of scientists face many challenges. However, HTLV scientists and clinicians displayed exciting new approaches and discoveries during plenary talks and poster sessions. The conference encouraged research in HTLV infections and disease, fostered collaborations, and stimulated new partnerships between clinicians and scientists to encourage clinical trials and novel therapeutic interventions.

28th International Symposium on Shock Waves

CERN Document Server

2012-01-01

The University of Manchester hosted the 28th International Symposium on Shock Waves between 17 and 22 July 2011. The International Symposium on Shock Waves first took place in 1957 in Boston and has since become an internationally acclaimed series of meetings for the wider Shock Wave Community. The ISSW28 focused on the following areas: Blast Waves, Chemically Reacting Flows, Dense Gases and Rarefied Flows, Detonation and Combustion, Diagnostics, Facilities, Flow Visualisation, Hypersonic Flow, Ignition, Impact and Compaction, Multiphase Flow, Nozzle Flow, Numerical Methods, Propulsion, Richtmyer-Meshkov, Shockwave Boundary Layer Interaction, Shock Propagation and Reflection, Shock Vortex Interaction, Shockwave Phenomena and Applications, as well as Medical and Biological Applications. The two Volumes contain the papers presented at the symposium and serve as a reference for the participants of the ISSW 28 and individuals interested in these fields.

14 CFR 330.31 - What data must air carriers submit concerning ASMs or RTMs?

Science.gov (United States)

2010-01-01

... combination passenger/cargo carrier, you must have submitted your August 2001 total completed ASM report to... correct an error that you document to the Department, you must not alter the ASM or RTM reports you...

Technical Challenge and Demonstration of Advanced Solution Monitoring and Measurement System (ASMS)

International Nuclear Information System (INIS)

Takaya, A.; Mukai, Y.; Nakamura, H.; Hosoma, T.; Yoshimoto, K.; Tamura, T.; Iwamoto, T.

2010-01-01

JNFL and JAEA have collaboratively started to develop an Advanced Solution Measurement and monitoring System (ASMS) as a part of technical challenge intended for next generation safeguards NDA equipment. After we completed feasibility study by using small detectors, the second stage of ASMS has installed into PCDF tank located in a cell, and then tested and calibrated by Pu nitrate solution experimentally. There was no experience measuring around 50kg Pu inventory directly, so it was very challenging work. The conventional SMMS (Solution Monitoring and Measurement System) that is composed of precision manometers acquires density, level and temperature of solution, so that the sampling and analysis are essential to obtain the nuclear material amount in the tank. The SMMS has two weak points on verification and monitoring of the nuclear material flow and inventory; (1) Direct measurement of the inventory cannot be done, (2) Solution rework and reagent adjustment operation in actual plant will make miss-interpretation on the monitoring evaluation. The purpose of ASMS development is to establish quantitative plutonium mass measurement technique directly by NDA of high concentrated pure plutonium nitrate solution and monitoring capability for solution transfers in a process. The merits of ASMS are considered below; (1) Provide direct Pu measurement and continuous monitoring capability, (2) Eliminate sampling and analysis at IIV, (3) Reduce unmeasured inventory. The target of the measurement uncertainty of ASMS is set less than 6% (1sigma) which is equivalent to meet the detection level of the partial defect at IIV by NDA. Known-alpha coincidence counting technique is applied to the ASMS, which is similar to the NDAs for MOX powder as a principle measurement technique. Especially, three following points are key techniques to establish ASMS. (1) Pre-determination of plutonium isotopic composition because it impacts alpha and rho-zero values to obtain multiplication

Design Procedure of Graphite Components by ASME HTR Codes

Energy Technology Data Exchange (ETDEWEB)

Kang, Ji-Ho; Jo, Chang Keun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2016-10-15

In this study, the ASME B and PV Code, Subsection HH, Subpart A, design procedure for graphite components of HTRs was reviewed and the differences from metal materials were remarked. The Korean VHTR has a prismatic core which is made of multiple graphite blocks, reflectors, and core supports. One of the design issues is the assessment of the structural integrity of the graphite components because the graphite is brittle and shows quite different behaviors from metals in high temperature environment. The American Society of Mechanical Engineers (ASME) issued the latest edition of the code for the high temperature reactors (HTR) in 2015. In this study, the ASME B and PV Code, Subsection HH, Subpart A, Graphite Materials was reviewed and the special features were remarked. Due the brittleness of graphites, the damage-tolerant design procedures different from the conventional metals were adopted based on semi-probabilistic approaches. The unique additional classification, SRC, is allotted to the graphite components and the full 3-D FEM or equivalent stress analysis method is required. In specific conditions, the oxidation and viscoelasticity analysis of material are required. The fatigue damage rule has not been established yet.

Design Procedure of Graphite Components by ASME HTR Codes

International Nuclear Information System (INIS)

Kang, Ji-Ho; Jo, Chang Keun

2016-01-01

In this study, the ASME B and PV Code, Subsection HH, Subpart A, design procedure for graphite components of HTRs was reviewed and the differences from metal materials were remarked. The Korean VHTR has a prismatic core which is made of multiple graphite blocks, reflectors, and core supports. One of the design issues is the assessment of the structural integrity of the graphite components because the graphite is brittle and shows quite different behaviors from metals in high temperature environment. The American Society of Mechanical Engineers (ASME) issued the latest edition of the code for the high temperature reactors (HTR) in 2015. In this study, the ASME B and PV Code, Subsection HH, Subpart A, Graphite Materials was reviewed and the special features were remarked. Due the brittleness of graphites, the damage-tolerant design procedures different from the conventional metals were adopted based on semi-probabilistic approaches. The unique additional classification, SRC, is allotted to the graphite components and the full 3-D FEM or equivalent stress analysis method is required. In specific conditions, the oxidation and viscoelasticity analysis of material are required. The fatigue damage rule has not been established yet

Utilização de Ecolife® e Acibenzolar-s-metil (ASM no controle da antracnose da banana em pós-colheita Use of Ecolife® and Acibenzolar-S-metil (ASM on the control of antracnosis in banana post-harvest

Directory of Open Access Journals (Sweden)

Luciano Marinho Furtado

2010-09-01

Full Text Available O objetivo deste trabalho foi avaliar a ação dos produtos ASM e Ecolife no controle da antracnose pós-colheita em frutos de banana. Frutos sadios de banana, variedades maçã, prata, pacovan e cacau , em fase intermediária de maturação, foram imersos previamente em soluções de ASM e Ecolife e inoculados com Colletotrichum musae. Utilizou-se o delineamento inteiramente casualizado, em esquema fatorial com quatro repetições. Os resultados apresentados demonstraram a eficácia dos produtos nas concentrações de 5 ml/ L (Ecolife e 0,50g/ L (ASM no controle da antracnose nas variedades analisa das. A variedade cacau apresentou menor lesão quando tratada com o Ecolife (5,79 mm. Com relação ao efeito do ASM, a bana na prata demonstrou um melhor resultado, com tamanho médio de lesão de 5,62 mm. Com o decorrer do processo de maturação dos frutos houve um decréscimo na severidade da doença nas quatro variedades estudadas, exceto no tratamento testemunha, que continuou apresentando aumento no tamanho das lesões nos frutos e atingir a polpa ao final da maturação.The aim of this work was to evaluate the effects of ASM and Ecolife on the control of post-harvest antracnosis in banana. Banana fruits of Maçã, Prata, Pacovan and Figo varieties, at intermediate stage of maturation, were immersed in solutions of ASM and Ecolife and inoculated with Colletotrichum musae A completely randomized design was used, at a factorial scheme 4x2 (four varieties x two products with four replicates. The presented results demonstrated the susceptibility of the fruits to the disease, mainly Maça variety with lesion of 17,99 mm. It was demosntrated the effectiveness of products at concentrations of 5ml. L-1 (Ecolife and 0.50g. L-1 (ASM on antracnosis control. The Figo variety presented the smallest injuries when treated with Ecolife (5.79 mm. Regarding ASM effects, Prata variety demonstrated the best performance, with 5.62 mm of injuries diameter

14th International Probabilistic Workshop

CERN Document Server

Taerwe, Luc; Proske, Dirk

2017-01-01

This book presents the proceedings of the 14th International Probabilistic Workshop that was held in Ghent, Belgium in December 2016. Probabilistic methods are currently of crucial importance for research and developments in the field of engineering, which face challenges presented by new materials and technologies and rapidly changing societal needs and values. Contemporary needs related to, for example, performance-based design, service-life design, life-cycle analysis, product optimization, assessment of existing structures and structural robustness give rise to new developments as well as accurate and practically applicable probabilistic and statistical engineering methods to support these developments. These proceedings are a valuable resource for anyone interested in contemporary developments in the field of probabilistic engineering applications.

Enabling Manufacturing Competitiveness and Economic Sustainability : Proceedings of the 4th International Conference on Changeable, Agile, Reconfigurable and Virtual production

CERN Document Server

2012-01-01

The changing manufacturing environment requires more responsive and adaptable manufacturing systems. The theme of the 4th International Conference on Changeable, Agile, Reconfigurable and Virtual production (CARV2011) is “Enabling Manufacturing Competitiveness and Economic Sustainability”. Leading edge research and best implementation practices and experiences, which address these important issues and challenges, are presented. The proceedings include advances in manufacturing systems design, planning, evaluation, control and evolving paradigms such as mass customization, personalization, changeability, re-configurability and flexibility. New and important concepts such as the dynamic product families and platforms, co-evolution of products and systems, and methods for enhancing manufacturing systems’ economic sustainability and prolonging their life to produce more than one product generation are treated. Enablers of change in manufacturing systems, production volume and capability scalability and man...

The ASM Curriculum Guidelines for Undergraduate Microbiology: A Case Study of the Advocacy Role of Societies in Reform Efforts.

Science.gov (United States)

Horak, Rachel E A; Merkel, Susan; Chang, Amy

2015-05-01

A number of national reports, including Vision and Change in Undergraduate Biology Education: A Call to Action, have called for drastic changes in how undergraduate biology is taught. To that end, the American Society for Microbiology (ASM) has developed new Curriculum Guidelines for undergraduate microbiology that outline a comprehensive curriculum for any undergraduate introductory microbiology course or program of study. Designed to foster enduring understanding of core microbiology concepts, the Guidelines work synergistically with backwards course design to focus teaching on student-centered goals and priorities. In order to qualitatively assess how the ASM Curriculum Guidelines are used by educators and learn more about the needs of microbiology educators, the ASM Education Board distributed two surveys to the ASM education community. In this report, we discuss the results of these surveys (353 responses). We found that the ASM Curriculum Guidelines are being implemented in many different types of courses at all undergraduate levels. Educators indicated that the ASM Curriculum Guidelines were very helpful when planning courses and assessments. We discuss some specific ways in which the ASM Curriculum Guidelines have been used in undergraduate classrooms. The survey identified some barriers that microbiology educators faced when trying to adopt the ASM Curriculum Guidelines, including lack of time, lack of financial resources, and lack of supporting resources. Given the self-reported challenges to implementing the ASM Curriculum Guidelines in undergraduate classrooms, we identify here some activities related to the ASM Curriculum Guidelines that the ASM Education Board has initiated to assist educators in the implementation process.

The ASM Curriculum Guidelines for Undergraduate Microbiology: A Case Study of the Advocacy Role of Societies in Reform Efforts

Directory of Open Access Journals (Sweden)

Rachel E.A. Horak

2015-03-01

Full Text Available A number of national reports, including Vision and Change in Undergraduate Biology Education: A Call to Action, have called for drastic changes in how undergraduate biology is taught. To that end, the American Society for Microbiology (ASM developed new Curriculum Guidelines for undergraduate microbiology that outline a comprehensive curriculum for any undergraduate introductory microbiology course or program of study. Designed to foster enduring understanding of core microbiology concepts, the Guidelines work synergistically with backwards course design to focus teaching on student-centered goals and priorities.  In order to qualitatively assess how the ASM Curriculum Guidelines are used by educators and learn more about the needs of microbiology educators, the ASM Education Board distributed two surveys to the ASM education community. In this report, we discuss results of these surveys (353 responses. We found that the ASM Curriculum Guidelines are being implemented in many different types of courses at all undergraduate levels. Educators indicated that the ASM Curriculum Guidelines were very helpful when planning courses and assessments. We discuss some specific ways in which the ASM Curriculum Guidelines have been used in undergraduate classrooms. The survey identified some barriers that microbiology educators faced when trying to adopt the ASM Curriculum Guidelines, including lack of time, lack of financial resources, and lack of supporting resources. Given the self-reported challenges to implementing the ASM Curriculum Guidelines in undergraduate classrooms, we identify here some activities related to the ASM Curriculum Guidelines that the ASM Education Board has initiated to assist educators in the implementation process.

4th IEA International CCS Regulatory Network Meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-07-01

On 9 and 10 May 2012, the IEA International CCS Regulatory Network (Network), launched in Paris in May 2008 to provide a neutral forum for CCS regulators, policy makers and stakeholders to share updates and views on CCS regulatory developments, held its fourth meeting at the International Energy Agency (IEA) offices in Paris, France. The aim of the meeting was to: provide an update on government efforts to develop and implement carbon capture and storage (CCS) legal and regulatory frameworks; and consider ways in which governments are dealing with some of the more difficult or complex aspects of CCS regulation. This report summarises the proceedings of the meeting.

ASME Section XI philosophy related to operating nuclear plant fatigue damage protection

International Nuclear Information System (INIS)

Gosselin, S.R.

1995-01-01

When faced with operating fatigue concerns, nuclear plants traditionally look to the requirements contained in the original construction design code, ASME Section 3, as a basis for component operability. These rules constitute the requirements for nuclear power plant vessel and component construction and, when combined with the Owner's Design Specification, provide reasonable assurance of reliable operation. However, once construction is complete and operation begins, the purpose of any subsequent evaluations shifts from component ''design qualification'' to component ''fitness for service.'' This is a role that has been assumed for ASME Section 11. This paper presents a philosophy, recently endorsed by the ASME Section 11 Executive Committee, intended to guide future Code activities regarding fatigue and its impact on component serviceability

4th International Conference on Biomedical Engineering in Vietnam

CERN Document Server

Toan, Nguyen; Khoa, Truong; Phuong, Tran; Development of Biomedical Engineering

2013-01-01

This volume presents the proceedings of the Fourth International Conference on the Development of Biomedical Engineering in Vietnam which was held in Ho Chi Minh City as a Mega-conference. It is kicked off by the Regenerative Medicine Conference with the theme “BUILDING A FACE” USING A REGENERATIVE MEDICINE APPROACH”, endorsed mainly by the Tissue Engineering and Regenerative Medicine International Society (TERMIS). It is followed by the Computational Medicine Conference, endorsed mainly by the Computational Surgery International Network (COSINE) and the Computational Molecular Medicine of German National Funding Agency; and the General Biomedical Engineering Conference, endorsed mainly by the International Federation for Medical and Biological Engineering (IFMBE). It featured the contributions of 435 scientists from 30 countries, including: Australia, Austria, Belgium, Canada, China, Finland, France, Germany, Hungary, India, Iran, Italy, Japan, Jordan, Korea, Malaysia, Netherlands, Pakistan, Poland, Ru...

12th Biennial International Conference on Baroque Music

Czech Academy of Sciences Publication Activity Database

Jonášová, Milada; Kapsa, Václav; Maňourová, L.

2007-01-01

Roč. 44, č. 1 (2007), s. 91-93 ISSN 0018-7003. [12th Biennial International Conference on Baroque Music . Varšava, 26.07.2006-30.07.2006] R&D Projects: GA AV ČR KJB800580502 Institutional research plan: CEZ:AV0Z90580513 Keywords : music * conference * baroque Subject RIV: AL - Art, Architecture, Cultural Heritage

12th International Symposium on Open Collaboration Companion

CERN Document Server

2016-01-01

Welcome to the proceedings of OpenSym 2016, the 12th international symposium on open collaboration! Open collaboration is collaboration that is egalitarian (everyone can join, no principled or artificial barriers to participation exist), meritocratic (decisions and status are merit-based rather than imposed) and self-organizing (processes adapt to people rather than people adapt to predefined processes).

Computer and Information Sciences III : 27th International Symposium on Computer and Information Sciences

CERN Document Server

Lent, Ricardo

2013-01-01

Information technology is the enabling foundation science and technology for all of human activity at the beginning of the 21st century, and advances in this area are crucial to all of us. These advances are taking place all over the world and can only be followed and perceived when researchers from all over the world assemble, and exchange their ideas in conferences such as the one presented in this proceedings volume regarding the 27th International Symposium on Computer and Information Systems, held at the Institut Henri Poincare' in Paris on October 3 and 4, 2012. Computer and Information Sciences III: 27th International Symposium on Computer and Information Sciences contains novel advances in the state of the art covering applied research in electrical and computer engineering and computer science, across the broad area of information technology. It provides access to the main innovative activities in research across the world, and points to the results obtained recently by some of the most active teams ...

Modification of the ASME code z-factor for circumferential surface crack in nuclear ferritic pipings

International Nuclear Information System (INIS)

Choi, Young Hwan; Chung, Yon Ki; Koh, Wan Young; Lee, Joung Bae

1996-01-01

The purpose of this paper is to modify the ASME Code Z-Factor, which is used in the evaluation of circumferential surface crack in nuclear ferritic pipings. The ASME Code Z-Factor is a load multiplier to compensate plastic load with elasto-plastic load. The current ASME Code Z-Factor underestimates pipe maximum load. In this study, the original SC. TNP method is modified first because the original SC. TNP method has a problem that the maximum allowable load predicted from the original SC. TNP method is slightly higher than that measured from the experiment. Then the new Z-Factor is developed using the modified SC. TNP method. The desirability of both the modified SC. TNP method and the new Z-Factor is examined using the experimental results for the circumferential surface crack in pipings. The results show that (1) the modified SC. TNP method is good for predicting the circumferential surface crack behavior in pipings, and (2) the Z-Factor obtained from the modified SC. TNP method well predicts the behavior of circumferential surface crack in ferritic pipings. 30 refs., 13 figs., 4 tabs. (author)

4th Workshop on Combinations of Intelligent Methods and Applications

CERN Document Server

Palade, Vasile; Prentzas, Jim

2016-01-01

This volume includes extended and revised versions of the papers presented at the 4th Workshop on “Combinations of Intelligent Methods and Applications” (CIMA 2014) which was intended to become a forum for exchanging experience and ideas among researchers and practitioners dealing with combinations of different intelligent methods in Artificial Intelligence. The aim is to create integrated or hybrid methods that benefit from each of their components. Some of the existing presented efforts combine soft computing methods (fuzzy logic, neural networks and genetic algorithms). Another stream of efforts integrates case-based reasoning or machine learning with soft-computing methods. Some of the combinations have been more widely explored, like neuro-symbolic methods, neuro-fuzzy methods and methods combining rule-based and case-based reasoning. CIMA 2014 was held in conjunction with the 26th IEEE International Conference on Tools with Artificial Intelligence (ICTAI 2014). .

4-th EPRI International conference on the water chemistry of the organic-fuel thermal power plants

International Nuclear Information System (INIS)

Petrova, T.I.; Martynova, O.I.

1995-01-01

Most actual problems on thermal power engineering are discussed at EPRI conferences on organic fuel, conducted every two years. Experience in realization of economically beneficial, ecologically feasible modes and their monitoring, accumulated in recent years, was formulated at the 4-th conference with wide participation

X-ray spectral study of the Th6p,5f electron states in ThO2 and ThF4

International Nuclear Information System (INIS)

Teterin, Y.A.; Nikitin, A.S.; Teterin, A.Y.; Ivanov, K.E.; Utkin, I.O.; Nerehov, V.A.; Ryzhkov, M.V.; Vukchevich, I.J.

2002-01-01

The study of the Th6p,5f electron states in Th, ThO 2 and ThF was carried out on the basis of the X-ray photoelectron fine spectral structure parameters in the binding energy range of 0-∼ 1000 eV, X-ray O 4,5 (Th) emission spectra of the shallow (0-∼50 eV) electrons and results of theoretical calculations. As a result, despite the absence of the Th5f electrons in thorium atoms, the Th5f atomic orbitals were established to participate in the formation of molecular orbitals in thorium dioxide and tetrafluoride. In the MO LCAO approximation this allowed to suggest the possible existence of filled Th5f electronic states in thorium compounds. On the basis of the X-ray O 4,5 (Th) emission spectral structure parameters the effective formation of the inner valence molecular orbitals in the studied compounds was confirmed. (authors)

14th International Conference on Particle Induced X-ray Emission ("PIXE 2015")

Science.gov (United States)

Przybyłowicz, Wojciech Józef; Pineda-Vargas, Carlos

2015-11-01

This special issue of Nuclear Instruments and Methods in Physics Research B contains the proceedings of the 14th International Conference on Particle Induced X-ray Emission ("PIXE 2015") that was held in Somerset West (South Africa) from 25th February to 3rd March 2015.

Spectrum of SMPD1 mutations in Asian-Indian patients with acid sphingomyelinase (ASM)-deficient Niemann-Pick disease.

Science.gov (United States)

Ranganath, Prajnya; Matta, Divya; Bhavani, Gandham SriLakshmi; Wangnekar, Savita; Jain, Jamal Mohammed Nurul; Verma, Ishwar C; Kabra, Madhulika; Puri, Ratna Dua; Danda, Sumita; Gupta, Neerja; Girisha, Katta M; Sankar, Vaikom H; Patil, Siddaramappa J; Ramadevi, Akella Radha; Bhat, Meenakshi; Gowrishankar, Kalpana; Mandal, Kausik; Aggarwal, Shagun; Tamhankar, Parag Mohan; Tilak, Preetha; Phadke, Shubha R; Dalal, Ashwin

2016-10-01

Acid sphingomyelinase (ASM)-deficient Niemann-Pick disease is an autosomal recessive lysosomal storage disorder caused by biallelic mutations in the SMPD1 gene. To date, around 185 mutations have been reported in patients with ASM-deficient NPD world-wide, but the mutation spectrum of this disease in India has not yet been reported. The aim of this study was to ascertain the mutation profile in Indian patients with ASM-deficient NPD. We sequenced SMPD1 in 60 unrelated families affected with ASM-deficient NPD. A total of 45 distinct pathogenic sequence variants were found, of which 14 were known and 31 were novel. The variants included 30 missense, 4 nonsense, and 9 frameshift (7 single base deletions and 2 single base insertions) mutations, 1 indel, and 1 intronic duplication. The pathogenicity of the novel mutations was inferred with the help of the mutation prediction software MutationTaster, SIFT, Polyphen-2, PROVEAN, and HANSA. The effects of the identified sequence variants on the protein structure were studied using the structure modeled with the help of the SWISS-MODEL workspace program. The p. (Arg542*) (c.1624C>T) mutation was the most commonly identified mutation, found in 22% (26 out of 120) of the alleles tested, but haplotype analysis for this mutation did not identify a founder effect for the Indian population. To the best of our knowledge, this is the largest study on mutation analysis of patients with ASM-deficient Niemann-Pick disease reported in literature and also the first study on the SMPD1 gene mutation spectrum in India. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Researching on knowledge architecture of design by analysis based on ASME code

International Nuclear Information System (INIS)

Bao Shiyi; Zhou Yu; He Shuyan

2003-01-01

The quality of knowledge-based system's knowledge architecture is one of decisive factors of knowledge-based system's validity and rationality. For designing the ASME code knowledge based system, this paper presents a knowledge acquisition method which is extracting knowledge through document analysis consulted domain experts' knowledge. Then the paper describes knowledge architecture of design by analysis based on the related rules in ASME code. The knowledge of the knowledge architecture is divided into two categories: one is empirical knowledge, and another is ASME code knowledge. Applied as the basement of the knowledge architecture, a general procedural process of design by analysis that is met the engineering design requirements and designers' conventional mode is generalized and explained detailed in the paper. For the sake of improving inference efficiency and concurrent computation of KBS, a kind of knowledge Petri net (KPN) model is proposed and adopted in expressing the knowledge architecture. Furthermore, for validating and verifying of the empirical rules, five knowledge validation and verification theorems are given in the paper. Moreover the research production is applicable to design the knowledge architecture of ASME codes or other engineering standards. (author)

Approaching application of risk-based inspection to ASME code section XI

International Nuclear Information System (INIS)

Hedden, Owen F.

1995-01-01

This paper will describe current efforts within the ASME Boiler and Pressure Vessel Committee's Subcommittee on Nuclear Inservice Inspection to introduce risk-based technology to optimize inservice inspection of nuclear power plants. The subcommittee is responsible for the content of ASME Boiler and Pressure Vessel Code Section XI, Rules for Inservice Inspection of Nuclear Power Plant Components. The paper will first provide the historical background for the inspection program currently in Section XI. It will then describe the development of new technology through the ASME Center for Research and Technology Development program. Next, the work now going on in two of the groups under the Section XI committee will be described in detail. Each of these two efforts is directed toward the application of new risk-based inspection technology to nuclear piping systems. Finally, the directions of additional research and applications of the technology will be discussed. (author)

Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency.

Science.gov (United States)

Acuña, Mariana; Castro-Fernández, Víctor; Latorre, Mauricio; Castro, Juan; Schuchman, Edward H; Guixé, Victoria; González, Mauricio; Zanlungo, Silvana

2016-10-21

Niemann-Pick disease (NPD) type A and B are recessive hereditary disorders caused by deficiency in acid sphingomyelinase (ASM). The p.Ala359Asp mutation has been described in several patients but its functional and structural effects in the protein are unknown. In order to characterize this mutation, we modeled the three-dimensional ASM structure using the recent available crystal of the mammalian ASM as a template. We found that the p.Ala359Asp mutation is localized in the hydrophobic core and far from the sphingomyelin binding site. However, energy function calculations using statistical potentials indicate that the mutation causes a decrease in ASM stability. Therefore, we investigated the functional effect of the p.Ala359Asp mutation in ASM expression, secretion, localization and activity in human fibroblasts. We found a 3.8% residual ASM activity compared to the wild-type enzyme, without changes in the other parameters evaluated. These results support the hypothesis that the p.Ala359Asp mutation causes structural alterations in the hydrophobic environment where ASM is located, decreasing its enzymatic activity. A similar effect was observed in other previously described NPDB mutations located outside the active site of the enzyme. This work shows the first full size ASM mutant model describe at date, providing a complete analysis of the structural and functional effects of the p.Ala359Asp mutation over the stability and activity of the enzyme. Copyright © 2016 Elsevier Inc. All rights reserved.

Electrochemical reactions of the Th4+/Th couple on the tungsten, aluminum and bismuth electrodes in chloride molten salt

International Nuclear Information System (INIS)

Liu, Kui; Yuan, Li-Yong; Liu, Ya-Lan; Zhao, Xiu-Liang; He, Hui; Ye, Guo-An; Chai, Zhi-Fang; Shi, Wei-Qun

2014-01-01

This work concerns the electrochemical behaviors of Th 4+ on the tungsten, aluminum and bismuth electrodes in the LiCl-KCl eutectic, respectively, at 773 K. Cyclic voltammetry and square wave voltammetry were employed to investigate the cathodic reduction of Th 4+ . The results demonstrate that the reduction of Th 4+ is a one step process with a transfer of 4 electrons. The reversibility of the Th 4+ /Th couple on the bismuth film and tungsten electrodes is directly confirmed by the CV. The diffusion coefficient is also calculated to be (2.23 ± 0.16) × 10 −5 and (7.19 ± 0.12) × 10 −5 cm 2 /s by applying both cyclic voltammetry and chronopotentiometry, respectively. A series of redox couples were confirmed to be associated with the formation of different kinds of Al-Th intermetallic compounds. Compared to Al electrode, a cathodic shift of the reduction potential of the Th 4+ is observed on the Al film electrode which is not conducive for the potentiostatic extraction of thorium. The cathodic depolarization gives a shift of 420 mV on the Al electrode, while 490 mV on the Bi film electrode for the reduction of Th 4+ compared to the inert W electrode. The reduction potential of Th 4+ on the Bi film electrode is 70 mV more anodic than that on the Al electrode. Potentiostatic electrolyses were carried out on an Al plate and Bi liquid electrode to confirm the formation of the Th alloys. Two Al-Th alloys (Al 3 Th and Al 2 Th) and one Bi-Th alloy (Bi 2 Th) were obtained, respectively

Roles of the outer membrane protein AsmA of Salmonella enterica in the control of marRAB expression and invasion of epithelial cells.

Science.gov (United States)

Prieto, Ana I; Hernández, Sara B; Cota, Ignacio; Pucciarelli, M Graciela; Orlov, Yuri; Ramos-Morales, Francisco; García-del Portillo, Francisco; Casadesús, Josep

2009-06-01

A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in phoP and wec mutants of S. enterica and increased the MIC of sodium deoxycholate for the parental strain ATCC 14028. Increased levels of marA mRNA were found in asmA, asmA dam, asmA phoP, and asmA wec strains of S. enterica, suggesting that lack of AsmA activates expression of the marRAB operon. Hence, asmA mutations may enhance bile resistance by inducing gene expression changes in the marRAB-controlled Mar regulon. In silico analysis of AsmA structure predicted the existence of one transmembrane domain. Biochemical analysis of subcellular fractions revealed that the asmA gene of S. enterica encodes a protein of approximately 70 kDa located in the outer membrane. Because AsmA is unrelated to known transport and/or efflux systems, we propose that activation of marRAB in asmA mutants may be a consequence of envelope reorganization. Competitive infection of BALB/c mice with asmA(+) and asmA isogenic strains indicated that lack of AsmA attenuates Salmonella virulence by the oral route but not by the intraperitoneal route. Furthermore, asmA mutants showed a reduced ability to invade epithelial cells in vitro.

The approach to analysis of significance of flaws in ASME section III and section XI

International Nuclear Information System (INIS)

Cowan, A.

1979-01-01

ASME III Appendix G and ASME XI Appendix A describe linear elastic fracture mechanics methods to assess the significance of defects in thick-walled pressure vessels for nuclear reactor systems. The assessment of fracture toughness, Ksub(Ic), is based upon recommendations made by a Task Group of the USA Pressure Vessel Research Committee and is dependent upon correlations with drop weight and Charpy V-notch data to give a lower bound of fracture toughness Ksub(IR). The methods used in the ASME Appendices are outlined noting that, whereas ASME III Appendix G defines a procedure for obtaining allowable pressure vessel loadings for normal service in the presence of a defect, ASME XI Appendix A defines methods for assessing the significance of defects (found by volumetric inspection) under normal and emergency and faulted conditions. The methods of analysis are discussed with respect to material properties, flaw characterisation, stress analysis and recommended safety factors; a short discussion is given on the applicability of the data and methods to other materials and non-nuclear structures. (author)

7th International Conference on Knowledge Management in Organizations (KMO)

CERN Document Server

Herrera, Francisco; Pérez, Javier; Rodríguez, Juan; 7th International Conference on Knowledge Management in Organizations: Service and Cloud Computing

2013-01-01

The seventh International Conference on Knowledge Management in Organizations (KMO) brings together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on knowledge management in organisations.   KMO 2012 provides an international forum for authors to present and discuss research focused on the role of knowledge management for innovative services in industries, to shed light on recent advances in cloud computing for KM as well as to identify future directions for researching the role of knowledge management in service innovation and how cloud computing can be used to address many of the issues currently facing KM in academia and industrial sectors. The conference took place at Salamanca in Spain on the 11th-13th July in 2012.

Neurospora crassa ASM-1 complements the conidiation defect in a stuA mutant of Aspergillus nidulans.

Science.gov (United States)

Chung, Dawoon; Upadhyay, Srijana; Bomer, Brigitte; Wilkinson, Heather H; Ebbole, Daniel J; Shaw, Brian D

2015-01-01

Aspergillus nidulans StuA and Neurospora crassa ASM-1 are orthologous APSES (ASM-1, PHD1, SOK2, Efg1, StuA) transcription factors conserved across a diverse group of fungi. StuA and ASM-1 have roles in asexual (conidiation) and sexual (ascospore formation) development in both organisms. To address the hypothesis that the last common ancestor of these diverse fungi regulated conidiation with similar genes, asm-1 was introduced into the stuA1 mutant of A. nidulans. Expression of asm-1 complemented defective conidiophore morphology and restored conidia production to wild type levels in stuA1. Expression of asm-1 in the stuA1 strain did not rescue the defect in sexual development. When the conidiation regulator AbaA was tagged at its C-terminus with GFP in A. nidulans, it localized to nuclei in phialides. When expressed in the stuA1 mutant, AbaA::GFP localized to nuclei in conidiophores but no longer was confined to phialides, suggesting that expression of AbaA in specific cell types of the conidiophore was conditioned by StuA. Our data suggest that the function in conidiation of StuA and ASM-1 is conserved and support the view that, despite the great morphological and ontogenic diversity of their condiphores, the last common ancestor of A. nidulans and N. crassa produced an ortholog of StuA that was involved in conidiophore development. © 2015 by The Mycological Society of America.

Proceedings of the 16th ACM SIGPLAN international conference on Functional programming

DEFF Research Database (Denmark)

Danvy, Olivier

Welcome to the 16th ACM SIGPLAN International Conference on Functional Programming -- ICFP'11. The picture, on the front cover, is of Mount Fuji, seen from the 20th floor of the National Institute of Informatics (NII). It was taken by Sebastian Fischer in January 2011. In Japanese, the characters...

Inservice inspection procedures and training according to the ASME code

International Nuclear Information System (INIS)

Greenwald, S.M.; Chockie, L.J.

1987-01-01

Mandatory training of the technical staff at a nuclear power plant is of paramount importance if we are to avoid costly plant shutdowns. This training should include the requirements for both Preservice and Inservice Inspection, in addition to Quality Assurance procedures as required by the American Society of Mechanical Engineers (ASME) Code. The training is best accomplished by utilizing instructors who are thoroughly familiar with plant operations and the ASME Code, as well as serving on one of the Code committees. This paper focuses on the Inservice Inspection procedures and the results of an intensive training effort to implement such procedures. (author)

Solid state physics and actinide spectroscopy with ThBr4 and ThCl4

International Nuclear Information System (INIS)

Genet, M.

1984-01-01

From the solid state physics to the optical spectroscopy of 5 f elements, we have described in details how ThBr 4 and ThCl 4 are acting an important role in the applied and basic research field. The possible applications are based on the scintillation properties of these crystals while the fundamental aspect is related to their special incommensurate structure which modulates the host properties of these matrices at low temperature. This very small perturbation of bromine atom positions have optical consequences on the absorption and emission of the actinide studied ions which are interpreted in function of the modulated structure parameters determined by inelastic and elastic neutron scattering and by Raman spectroscopy. The structural model proposed shows, for the first time, how the optical properties of the investigated ion are influenced by the sinusoidal displacements of the bromine atoms, leading to an energy continuum in the absorption and reducing the site symmetry from Dsub(2d) to a multisite of D 2 symmetry

The 16th International Geological Congress, Washington, 1933

Science.gov (United States)

Nelson, C.M.

2009-01-01

In 1933, the International Geological Congress (IGC) returned to the United States of America (USA) for its sixteenth meeting, forty-two years after the 5th IGC convened in Washington. The Geological Society of America and the U.S. Geological Survey (USGS) supplied the major part of the required extra-registration funding after the effects of the Great Depression influenced the 72th U.S. Congress not to do so. A reported 1, 182 persons or organizations, representing fifty-four countries, registered for the 16 th IGC and thirty-four countries sent 141 official delegates. Of the total number of registrants, 665 actually attended the meeting; 500 came from the USA; and fifteen had participated in the 5th IGC. The 16 th Meeting convened in the U.S. Chamber of Commerce Building from 22 to 29 July. The eighteen half-day scientific sections-orogenesis (four), major divisions of the Paleozoic (three), miscellaneous (three), batholiths and related intrusives (two), arid-region geomorphic processes and products (one), fossil man and contemporary faunas (one), geology of copper and other ore deposits (one), geology of petroleum (one), measuring geologic time (one), and zonal relations of metalliferous deposits (one)-included 166 papers, of which fifty (including several of the key contributions) appeared only by title. The Geological Society of Washington, the National Academy of Sciences, and the U.S. Bureau of Mines hosted or contributed to evening presentations or receptions. Twenty-eight of the 16th IGC's thirty new guidebooks and one new USGS Bulletin aided eight pre-meeting, seven during-meeting, and four post-meeting field trips of local, regional, or national scope. The remaining two new guidebooks outlined the USA's structural geology and its stratigraphic nomenclature. The 16th IGC published a two-volume monograph on the world's copper resources (1935) and a two-volume report of its proceedings (1936).

The ASME research task force on risk-based in-service inspection

International Nuclear Information System (INIS)

Balkey, K.R.; Chapman, O.J.V.

1997-01-01

The use of risk-based methods in the development of in-service inspection (ISI) and in-service testing (IST) programs for nuclear power plant and other industrial applications has been studied for the last several years through the American Society of Mechanical Engineers Centre for Research and Technology Development (ASME 1991, 1992, 1994, 1996). The results of this work are being used as a foundation to develop specific requirements for implementation of risk-based technology in ASME Codes and Standards, regulatory requirements and industry programs both in the U.S. and other countries. This paper provides a brief overview of the ASME Research Methodology and how it has been adapted for application to the inspection of piping within the USA. It also relates how the reliability of nondestructive examination (NDE) methods for pressure boundary components can impact the risk and discusses the relationship between this and NDE qualification/demonstration now being implemented in Europe and the USA. (orig.)

Electrochemical behavior of Th(IV) and its electrodeposition from ThF_4-LiCl-KCl melt

International Nuclear Information System (INIS)

Wang, Xianbin; Huang, Wei; Gong, Yu; Jiang, Feng; Zheng, Haiyang; Zhu, Tiejian; Long, Dewu; Li, Qingnuan

2016-01-01

The electrochemical behavior of Th(IV) ion on molybdenum (Mo) electrode was studied by cyclic voltammetry (CV) and square wave voltammetry (SWV) technologies at 773 K in ThF_4-LiCl-KCl melt. The reduction of Th(IV) to metal Th at −1.67 V (vs. Ag/AgCl) is a four-electron exchange process, which is quasi-reversible and diffusion-controlled. The diffusion coefficient (D) and activation energy of diffusion process for Th(IV) were determined to be 3.77 × 10"−"5 cm"2 s"−"1 and 59.2 kJ mol"−"1. The pulse potential electrolysis of ThF_4-LiCl-KCl melt revealed that 86.8% of Th(IV) can be separated from the melt based on the inductively coupled plasma atomic emission spectrometer (ICP-AES) results.

The 12th International Symposium on Spermatology

Science.gov (United States)

Aitken, R John; Cummins, Jim M; Nixon, Brett

2015-01-01

The 12th International Symposium of Spermatology continued the excellent tradition of this meeting since its inception in 1969 when the first Symposium was held in Italy under the Chairmanship of Professor Baccio Baccetti. This unique Symposium is held every 4 years and serves as a beacon for sperm cell biologists from all over the world, regardless of which species, animal or plant, they are working on. This willingness to embrace the fundamental biology of this distinctive cell type without species limitations is one of the hallmarks of this Symposium. For sperm biologists – it is our Olympics. The meeting in Newcastle, NSW brought together around 300 biologists from more than 22 different countries covering North and South America, Africa, Europe, Asia and Australia. Given the considerable distances and high cost involved in travelling to the East Coast of NSW, this was an outstanding outcome. The Symposium featured a series of 31 plenary lectures culminating in the prestigious Thaddeus Mann Memorial Lecture, which was delivered with typical grace and brilliance by Professor Masaru Okabe. PMID:25994646

Proceedings: 2001 ASME/EPRI Radwaste Workshop

International Nuclear Information System (INIS)

2001-01-01

Nuclear utilities continually evaluate methods to improve operations and reduce costs associated with radioactive waste management. The continuing deregulation process has increased the emphasis on this activity. The Annual ASME/EPRI Workshop facilitates this effort by communicating technology and management improvements throughout the industry. This workshop, restricted to utility radwaste professionals, also serves to communicate practical in-plant improvements with the opportunity to discuss them in detail

3D automatic anatomy segmentation based on iterative graph-cut-ASM.

Science.gov (United States)

Chen, Xinjian; Bagci, Ulas

2011-08-01

This paper studies the feasibility of developing an automatic anatomy segmentation (AAS) system in clinical radiology and demonstrates its operation on clinical 3D images. The AAS system, the authors are developing consists of two main parts: object recognition and object delineation. As for recognition, a hierarchical 3D scale-based multiobject method is used for the multiobject recognition task, which incorporates intensity weighted ball-scale (b-scale) information into the active shape model (ASM). For object delineation, an iterative graph-cut-ASM (IGCASM) algorithm is proposed, which effectively combines the rich statistical shape information embodied in ASM with the globally optimal delineation capability of the GC method. The presented IGCASM algorithm is a 3D generalization of the 2D GC-ASM method that they proposed previously in Chen et al. [Proc. SPIE, 7259, 72590C1-72590C-8 (2009)]. The proposed methods are tested on two datasets comprised of images obtained from 20 patients (10 male and 10 female) of clinical abdominal CT scans, and 11 foot magnetic resonance imaging (MRI) scans. The test is for four organs (liver, left and right kidneys, and spleen) segmentation, five foot bones (calcaneus, tibia, cuboid, talus, and navicular). The recognition and delineation accuracies were evaluated separately. The recognition accuracy was evaluated in terms of translation, rotation, and scale (size) error. The delineation accuracy was evaluated in terms of true and false positive volume fractions (TPVF, FPVF). The efficiency of the delineation method was also evaluated on an Intel Pentium IV PC with a 3.4 GHZ CPU machine. The recognition accuracies in terms of translation, rotation, and scale error over all organs are about 8 mm, 10 degrees and 0.03, and over all foot bones are about 3.5709 mm, 0.35 degrees and 0.025, respectively. The accuracy of delineation over all organs for all subjects as expressed in TPVF and FPVF is 93.01% and 0.22%, and all foot bones for

3D automatic anatomy segmentation based on iterative graph-cut-ASM

International Nuclear Information System (INIS)

Chen, Xinjian; Bagci, Ulas

2011-01-01

Purpose: This paper studies the feasibility of developing an automatic anatomy segmentation (AAS) system in clinical radiology and demonstrates its operation on clinical 3D images. Methods: The AAS system, the authors are developing consists of two main parts: object recognition and object delineation. As for recognition, a hierarchical 3D scale-based multiobject method is used for the multiobject recognition task, which incorporates intensity weighted ball-scale (b-scale) information into the active shape model (ASM). For object delineation, an iterative graph-cut-ASM (IGCASM) algorithm is proposed, which effectively combines the rich statistical shape information embodied in ASM with the globally optimal delineation capability of the GC method. The presented IGCASM algorithm is a 3D generalization of the 2D GC-ASM method that they proposed previously in Chen et al.[Proc. SPIE, 7259, 72590C1-72590C-8 (2009)]. The proposed methods are tested on two datasets comprised of images obtained from 20 patients (10 male and 10 female) of clinical abdominal CT scans, and 11 foot magnetic resonance imaging (MRI) scans. The test is for four organs (liver, left and right kidneys, and spleen) segmentation, five foot bones (calcaneus, tibia, cuboid, talus, and navicular). The recognition and delineation accuracies were evaluated separately. The recognition accuracy was evaluated in terms of translation, rotation, and scale (size) error. The delineation accuracy was evaluated in terms of true and false positive volume fractions (TPVF, FPVF). The efficiency of the delineation method was also evaluated on an Intel Pentium IV PC with a 3.4 GHZ CPU machine. Results: The recognition accuracies in terms of translation, rotation, and scale error over all organs are about 8 mm, 10 deg. and 0.03, and over all foot bones are about 3.5709 mm, 0.35 deg. and 0.025, respectively. The accuracy of delineation over all organs for all subjects as expressed in TPVF and FPVF is 93.01% and 0.22%, and

Report of the 4th European Zebrafish Principal Investigator Meeting.

Science.gov (United States)

Lopes, Susana S; Distel, Martin; Linker, Claudia; Fior, Rita; Monteiro, Rui; Bianco, Isaac H; Portugues, Ruben; Strähle, Uwe; Saúde, Leonor

2016-12-01

The European Zebrafish Principal Investigator Meeting (EZPM) is an ideal forum for group leaders using this fantastic animal model not only to discuss science but also to strengthen their interactions, to push forward technological advances, and to define guidelines for the use of this fish in research. The city of Lisbon (Portugal) was voted by the European group leaders to be the setting for the 4th EZPM, and the organizing committee, composed by Leonor Saúde (iMM Lisboa, PT), Susana Lopes (CEDOC, PT), Michael Orger (Champalimaud Foundation, PT), Rui Oliveira (ISPA, PT), and António Jacinto (CEDOC, PT), was very enthusiastic to organize a productive event. The 4th EZPM took place from March 15 to 19 at Pavilhão do Conhecimento, a Science Museum and Educational Center winner of The Great Prize FAD of Arquitecture 1999 and The Society for Environmental Graphic Design Award 2011. Over 5 days, 135 group leaders (89 men and 46 women) coming from 19 different European countries and also from the United States, Turkey, Israel, Chile, and Singapore presented and discussed their recent research achievements. In addition to the scientific oral and poster presentations, the group leaders gathered in very lively community sessions on morphants versus mutants (chaired by Didier Stainier, Max Planck Institute for Heart and Lung Research, DE), funding issues (chaired by Uwe Strahle, KIT-ITG, DE), and gender equality (chaired by Corinne Houart, KCL, United Kingdom). One of the highlights of the 4th EZPM was the guided visit to Oceanário de Lisboa, an international award-winning place that celebrates life with a stunning display of living aquatic creatures.

5th International Symposium on Experimental Mechanics (5-ISEM) and 9th Symposium on Optics in Industry

CERN Document Server

Furlong, Cosme; Barrientos, Bernardino; Pryputniewicz, Ryszard

2017-01-01

This book contains papers of the 5th International Symposium on Experimental Mechanics (5-ISEM) and the 9th Symposium on Optics in Industry (9-SOI), whose general theme is Emerging Challenges for Experimental Mechanics in Energy and Environmental Applications. These symposia are organized by Centro de Investigaciones en Optica (CIO) and Mexican Academy for Optics (AMO), under the sponsorship of the Society of Experimental Mechanics (SEM) and other national and international Organizations; Symposia are interdisciplinary forums for engineers, technicians, researchers and managers involved in all fields of Optics, Opto-mechatronics, Mechanics and Mechanical Engineering. · Addresses a broad readership including graduate and postgraduate students, researchers, and engineers working in experimental mechanics and in the application of optical methods · Covers a broad spectrum of topics highlighting the use of optical methods in experimental mechanics, energy, and in the environment.

Revision of the ASME nuclear quality assurance standard and its historical background

International Nuclear Information System (INIS)

Suzuki, Tetsuya

2009-01-01

ASME NQA-1-2008 'Quality Assurance Requirements for Nuclear Facility Applications' will be endorsed by US NRC by the end of 2009. This standard will apply to design, construction and operation of nuclear power plants newly erected in USA. It is important to Japanese vendors developing nuclear business in USA. Historical background, significance of revision and main revised points of the ASME nuclear quality assurance standard are described in the present paper. (T. Tanaka)

Advances in neutron capture therapy 2006. Proceedings of 12th international congress on neutron capture therapy

International Nuclear Information System (INIS)

Nakagawa, Yoshinobu; Kobayashi, Tooru; Fukuda, Hiroshi

2006-01-01

The Twelfth International Congress on Neutron Capture Therapy (ICNCT-12) is being held from October 9th to 13th, 2006 at the Kagawa International Congress Hall in Takamatsu, Kagawa, Japan. The main theme of the congress is From the past to the Future'. Five symposiums were organized to accommodate all the contributions from the international scientific committees of the International Society for Neutron Capture Therapy (ISNCT), and two symposiums were added to balance the number of fields of specialties. The seven symposiums for ICNCT-12 are as follows: 1) Clinical Results of BNCT for Brain Tumors, 2) Dosimetry, 3) Treatment Planning system, 4) Drug Delivery System, 5) Biomedical and General Matters, 6) BNCT Systems using Accelerators, 7) New Applications and Protocols for BNCT. There are a total of 195 presentations in this congress: 3 special lectures, 34 symposium presentations, 10 presentations in two special sessions from the recipients of the Ralph G. Fairchild Award, 70 presentations in the oral parallel sessions and 78 presentations in the poster sessions. A compilation of 169 papers are published in this proceedings. The 165 of the presented papers are indexed individually. (J.P.N.)

Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition.

Science.gov (United States)

Allen, Jodi C; Seidel, Petra; Schlosser, Tobias; Ramsay, Emma E; Ge, Qi; Ammit, Alaina J

2012-01-01

Hyperplasia of airway smooth muscle (ASM) is a feature of the remodelled airway in asthmatics. We examined the antiproliferative effectiveness of the corticosteroid dexamethasone on expression of the key regulator of G(1) cell cycle progression-cyclin D1-in ASM cells from nonasthmatics and asthmatics stimulated with the mitogen platelet-derived growth factor BB. While cyclin D1 mRNA and protein expression were repressed in cells from nonasthmatics in contrast, cyclin D1 expression in asthmatics was resistant to inhibition by dexamethasone. This was independent of a repressive effect on glucocorticoid receptor translocation. Our results corroborate evidence demonstrating that corticosteroids inhibit mitogen-induced proliferation only in ASM cells from subjects without asthma and suggest that there are corticosteroid-insensitive proliferative pathways in asthmatics.

37th International MATADOR Conference

CERN Document Server

Li, Lin

2013-01-01

Presented here are 97 refereed papers given at the 37th MATADOR Conference held at The University of Manchester in July 2012. The MATADOR series of conferences covers the topics of Manufacturing Automation and Systems Technology, Applications, Design, Organisation and Management, and Research.   The proceedings of this conference contain original papers contributed by researchers from many countries on different continents. The papers cover the principles, techniques and applications in aerospace, automotive, biomedical, energy, consumable goods and process industries.    The papers in this volume reflect: the importance of manufacturing to international wealth creation; the emerging fields of micro- and nano-manufacture; the increasing trend towards the fabrication of parts using lasers; the growing demand for precision engineering and part inspection techniques, and the changing trends in manufacturing within a global environment. .

Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.

Science.gov (United States)

Contreras, Francisco; Prado, Carolina; González, Hugo; Franz, Dafne; Osorio-Barrios, Francisco; Osorio, Fabiola; Ugalde, Valentina; Lopez, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Alvaro; Pacheco, Rodrigo

2016-05-15

Dopamine receptor D3 (DRD3) expressed on CD4(+) T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 signaling affects T cell-mediated immunity remains unknown. In this study, we report that TCR stimulation on mouse CD4(+) T cells induces DRD3 expression, regardless of the lineage specification. Importantly, functional analyses performed in vivo using adoptive transfer of OVA-specific OT-II cells into wild-type recipients show that DRD3 deficiency in CD4(+) T cells results in attenuated differentiation of naive CD4(+) T cells toward the Th1 phenotype, exacerbated generation of Th2 cells, and unaltered Th17 differentiation. The reciprocal regulatory effect of DRD3 signaling in CD4(+) T cells favoring Th1 generation and impairing the acquisition of Th2 phenotype was also reproduced using in vitro approaches. Mechanistic analysis indicates that DRD3 signaling evokes suppressor of cytokine signaling 5 expression, a negative regulator of Th2 development, which indirectly favors acquisition of Th1 phenotype. Accordingly, DRD3 deficiency results in exacerbated eosinophil infiltration into the airways of mice undergoing house dust mite-induced allergic response. Interestingly, our results show that, upon chronic inflammatory colitis induced by transfer of naive CD4(+) T cells into lymphopenic recipients, DRD3 deficiency not only affects Th1 response, but also the frequency of Th17 cells, suggesting that DRD3 signaling also contributes to Th17 expansion under chronic inflammatory conditions. In conclusion, our findings indicate that DRD3-mediated signaling in CD4(+) T cells plays a crucial role in the balance of effector lineages, favoring the inflammatory potential of CD4(+) T cells. Copyright © 2016 by The American Association of Immunologists, Inc.

Contributions to the 12th. International Cryogenic Engineering Conference

International Nuclear Information System (INIS)

Anon.

1988-01-01

The report consists of two papers read at the 12 th International Cryogenic Engineering Conference Held in Southampton from 12 to 15 July 1988. The first deals with the design of a conductor for NET machine; the second one gives the description of the liquid Nitrogen cooling system of the FTU tokamak

7th International Workshop on Natural Computing

CERN Document Server

Hagiya, Masami

2015-01-01

This book highlights recent advances in natural computing, including biology and its theory, bio-inspired computing, computational aesthetics, computational models and theories, computing with natural media, philosophy of natural computing and educational technology. It presents extended versions of the best papers selected from the symposium “7th International Workshop on Natural Computing” (IWNC7), held in Tokyo, Japan, in 2013. The target audience is not limited to researchers working in natural computing but also those active in biological engineering, fine/media art design, aesthetics and philosophy.

9th International Conference on Practical Applications of Computational Biology and Bioinformatics

CERN Document Server

Rocha, Miguel; Fdez-Riverola, Florentino; Paz, Juan

2015-01-01

This proceedings presents recent practical applications of Computational Biology and  Bioinformatics. It contains the proceedings of the 9th International Conference on Practical Applications of Computational Biology & Bioinformatics held at University of Salamanca, Spain, at June 3rd-5th, 2015. The International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB) is an annual international meeting dedicated to emerging and challenging applied research in Bioinformatics and Computational Biology. Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next generation sequencing technologies, together with novel and ever evolving distinct types of omics data technologies, have put an increasingly complex set of challenges for the growing fields of Bioinformatics and Computational Biology. The analysis o...

Proceedings: 2000 ASME/EPRI Radwaste Workshop

International Nuclear Information System (INIS)

2001-01-01

Nuclear utilities are continually evaluating methods to improve operations and reduce costs associated with radioactive waste management. The continuing deregulation process has added increased emphasis to this activity. The Annual ASME/EPRI Workshop facilitates this effort by communicating technological and managerial improvements throughout the industry. This workshop, restricted to utility radwaste professionals, also serves to communicate practical in-plant improvements with the opportunity to discuss them in detail

Probing the mysteries of the X-ray binary 4U 1210-64 with ASM, PCA, MAXI, BAT, and Suzaku

Energy Technology Data Exchange (ETDEWEB)

Coley, Joel B.; Corbet, Robin H. D.; Mukai, Koji; Pottschmidt, Katja, E-mail: jcoley1@umbc.edu [University of Maryland Baltimore County, 1000 Hilltop Cir, Baltimore, MD 21250 (United States)

2014-10-01

4U 1210-64 has been postulated to be a high-mass X-ray binary powered by the Be mechanism. X-ray observations with Suzaku, the ISS Monitor of All-sky X-ray Image (MAXI), and the Rossi X-ray Timing Explorer Proportional Counter Array (PCA) and All Sky Monitor (ASM) provide detailed temporal and spectral information on this poorly understood source. Long-term ASM and MAXI observations show distinct high and low states and the presence of a 6.7101 ± 0.0005 day modulation, interpreted as the orbital period. Folded light curves reveal a sharp dip, interpreted as an eclipse. To determine the nature of the mass donor, the predicted eclipse half-angle was calculated as a function of inclination angle for several stellar spectral types. The eclipse half-angle is not consistent with a mass donor of spectral type B5 V; however, stars with spectral types B0 V or B0-5 III are possible. The best-fit spectral model consists of a power law with index Γ = 1.85{sub −0.05}{sup +0.04} and a high-energy cutoff at 5.5 ± 0.2 keV modified by an absorber that fully covers the source as well as partially covering absorption. Emission lines from S XVI Kα, Fe Kα, Fe XXV Kα, and Fe XXVI Kα were observed in the Suzaku spectra. Out of eclipse, the Fe Kα line flux was strongly correlated with unabsorbed continuum flux, indicating that the Fe I emission is the result of fluorescence of cold dense material near the compact object. The Fe I feature is not detected during eclipse, further supporting an origin close to the compact object.

Assessment of ASME code examinations on regenerative, letdown and residual heat removal heat exchangers

International Nuclear Information System (INIS)

Gosselin, Stephen R.; Cumblidge, Stephen E.; Anderson, Michael T.; Simonen, Fredric A.; Tinsley, G A.; Lydell, B.; Doctor, Steven R.

2005-01-01

Inservice inspection requirements for pressure retaining welds in the regenerative, letdown, and residual heat removal heat exchangers are prescribed in Section XI Articles IWB and IWC of the ASME Boiler and Pressure Vessel Code. Accordingly, volumetric and/or surface examinations are performed on heat exchanger shell, head, nozzle-to-head, and nozzle-to-shell welds. Inspection difficulties associated with the implementation of these Code-required examinations have forced operating nuclear power plants to seek relief from the U.S. Nuclear Regulatory Commission. The nature of these relief requests are generally concerned with metallurgical, geometry, accessibility, and radiation burden. Over 60% of licensee requests to the NRC identify significant radiation exposure burden as the principle reason for relief from the ASME Code examinations on regenerative heat exchangers. For the residual heat removal heat exchangers, 90% of the relief requests are associated with geometry and accessibility concerns. Pacific Northwest National Laboratory was funded by the NRC Office of Nuclear Regulatory Research to review current practice with regard to volumetric and/or surface examinations of shell welds of letdown heat exchangers regenerative heat exchangers and residual (decay) heat removal heat exchangers Design, operating, common preventative maintenance practices, and potential degradation mechanisms are reviewed. A detailed survey of domestic and international PWR-specific operating experience was performed to identify pressure boundary failures (or lack of failures) in each heat exchanger type and NSSS design. The service data survey was based on the PIPExp- database and covers PWR plants worldwide for the period 1970-2004. Finally a risk assessment of the current ASME Code inspection requirements for residual heat removal, letdown, and regenerative heat exchangers is performed. The results are then reviewed to discuss the examinations relative to plant safety and

Proceedings of 6th International Microbeam Workshop/12th L.H. Gray Workshop Microbeam Probes of Cellular Radiation Response

International Nuclear Information System (INIS)

Prise, Kevin M.

2004-01-01

The extended abstracts which are submitted here present a summary of the proceedings of the 6th International Workshop/12th LH Gray Workshop: Microbeam Probes of Cellular Radiation Response, held at St. Catherine's College, University of Oxford, UK on March, 29th-31st, 2003. In 1993 the 4th LH Gray Workshop entitled ''Microbeam Probes of Cellular Radiation Response'' was held at the Gray Cancer Institute in Northwood. This was organized by Prof BD Michael, Dr M. Folkard and Dr KM Prise and brought together 40 participants interested in developing and applying new microbeam technology to problems in radiation biology (1). The workshop was an undoubted success and has spawned a series of subsequent workshops every two years. In the past, these workshops have been highly successful in bringing together groups interested in developing and applying micro-irradiation techniques to the study of cell and tissue damage by ionizing radiations. Following the first microbeam workshop, there has been a rapid growth in the number of centres developing radiobiology microbeams, or planning to do so and there are currently 15-20 worldwide. Much of the recent research using microbeams has used them to study low-dose effects and ''non-targeted'' responses such bystander effects, genomic instability and adaptive responses. The goal of the 6th workshop was to build on our knowledge of the development of microbeam approaches and the application to radiation biology in the future with the meeting stretching over a 3 day period. Over 80 participants reviewed the current state of radiobiology microbeam research worldwide and reported on new technological developments both in the fields of physics and biology

Rethinking ASME III seismic analysis for piping operability evaluations

International Nuclear Information System (INIS)

Adams, T.M.; Stevenson, J.D.

1994-01-01

It has been recognized since the mid 1980's that there are very large seismic margins to failure for nuclear piping systems when designed using current industry practice, design criteria, and methods. As a result of this realization there are or have been approximately eighteen initiatives within the ASME , Boiler and Pressure Vessel Code Section III, Division 1, in the form of proposed code cases and proposed code text changes designed to reduce these failure margins to more realistic values. For the most part these initiatives have concentrated on reclassifying seismic inertia stresses in the piping as secondary and increasing the allowable stress limits permitted by Section III of the ASME, Boiler Code. This paper focuses on the application of non-linear spectral analysis methods as a method to reduce the input seismic demand determination and thereby reduce the seismic failure margins. The approach is evaluated using the ASME Boiler Pressure Vessel Code Section III Subgroup on Design benchmark procedure as proposed by the Subgroup's Special Task Group on Integrated Piping Criteria. Using this procedure, criteria are compared to current code criterion and analysis methods, and several other of the currently proposed Boiler and Pressure Vessel, Section III, changes. Finally, the applicability of the non-linear spectral analysis to continued Safe Operation Evaluations is reviewed and discussed

CT and MRI findings of 4th ventricular tumors

International Nuclear Information System (INIS)

Kim, Taek Geun; Ro, Hee Jeong; Byun, Jae Young; Lee, Han Jin; Chung, Myung Hee; Choi, Kyu Ho; Shinn, Kyung Sub

1994-01-01

The purpose of our study is to evaluate characteristic features of 4th ventricular tumors in CT and MRI. Pathologically proved 9 patients with 4th ventricular tumor were examined by CT and/or MRI. 4th ventricular tumors were ependymoma(4 cases), medulloblastoma(2 case), choroid plexus papilloma(2 cases), and oligodendroglioma(1 cases). Include in our study were only those mass lesions that were located at surgery predominantly within 4th ventricle with or without ventricular expansion. The origin of 4th ventricular tumor was the roof (ependymoma 3 cases, medulloblastoma 2 cases), the floor (ependymoma 1 cases), and the undetermined(remaining 3 case). On MRI, all tumors were hypointense except ependymoma (3 cases) showing isointensity on T1WI. All tumors were hypointense on PDWI and T2WI. On Gd-DTPA enhanced T1WI, strong enhancement was seen in all but ependymoma(1 cases) which showed mild enhancement. On CT, as compared with MR images, various density on precontrast and postcontrast images were seen. Calcification was seen in choroid plexus papilloma(1 caes) and oligodendroglioma(1 cases). Hydrocephalus is seen in all cases except ependymoma(2 cases) and oligodendroglioma(1 case). Hemorrhage within tumor was present only in ependymoma(2 cases). Cystic change or necrosis of tumor was seen in ependymoma(3 cases), choroid plexus papilloma(1 case), and oligodendroglioma(1 case). Peritumoral edema was seen in medulloblastoma(1 case). Extension through the foramen Luschka and the Megendie was seen in ependymoma (2 cases), choroid plexus(2 cases), and medulloblastoma (1 case). Seeing along the CSF pathway was seen only in ependymoma(2 case). The results od our study may suggest that specific diagnosis of 4th ventricular tumor can be suggested preoperatively by analysing the origin in 4th ventricle, difference of CT density or MRI signal intensity, presence of extension or seeding through cerebrospinal fluid of the lesion

Special Issue the 12th International Conference on Substorms

Science.gov (United States)

Shiokawa, Kazuo; Fok, Mei-Ching; Fujimoto, Masaki

2016-01-01

The 12th International Conference on Substorms (ICS-12) was held at the Ise-Shima Royal Hotel in Shima, Japan, on November 10-14, 2014. There were 125 attendees including 68 from foreign countries. The ICS has been held every 2 years since 1992 to discuss substorms, which are fundamental global-scale disturbances in the Earth's magnetosphere. The year 2014 marked the 50th anniversary of the first publication about substorms (Akasofu 1964). The conference included three tutorial lecturers (Profs. S.-I. Akasofu, V. Angelopoulous, and D. Baker), as well as many international scientists, to discuss substorm processes in the tail, their Interactions with the inner magnetosphere and the ionosphere, substorm currents and their dynamics and energetics, the role of MagnetoHydroDynamics (MHD) and kinetic instabilities, storm-substorm relationships, ULFELFVLF waves, and non-Earth substorm-like features. Prof. Akasofu also gave an evening talk about the history of auroral research since the nineteenth century with photographs that inspired and intrigued the young scientists and students in attendance.

Internal fixation of proximal fractures of the 2nd and 4th metacarpal and metatarsal bones using bioabsorbable screws.

Science.gov (United States)

Mageed, M; Steinberg, T; Drumm, N; Stubbs, N; Wegert, J; Koene, M

2018-03-01

Fractures involving the proximal one-third of the splint bone are relatively rare and are challenging to treat. A variety of management techniques have been reported in the literature. The aim of this retrospective case series was to describe the clinical presentation and evaluate the efficacy of bioabsorbable polylactic acid screws in internal fixation of proximal fractures of the 2nd and 4th metacarpal and metatarsal bones in horses. The medical records, diagnostic images and outcome of all horses diagnosed with a proximal fracture of the splint bones and treated with partial resection and internal fixation of the proximal stump using bioabsorbable polylactic acid screws between 2014 and 2015 were reviewed. Eight horses met the inclusion criteria. The results showed that there were no complications encountered during screw placement or postoperatively. Six horses returned to full work 3 months after the operation and two horses remained mildly lame. On follow-up radiographs 12 months postoperatively (n = 2) the screws were not completely absorbed. The screws resulted in a cone-shaped radiolucency, which was progressively replaced from the outer margins by bone sclerosis. The use of bioabsorbable screws for fixation of proximal fractures of the splint bone appears to be a safe and feasible technique and may offer several advantages over the use of traditional metallic implants. © 2018 Australian Veterinary Association.

ThDof1.4 and ThZFP1 constitute a transcriptional regulatory cascade involved in salt or osmotic stress in Tamarix hispida.

Science.gov (United States)

Zang, Dandan; Wang, Lina; Zhang, Yiming; Zhao, Huimin; Wang, Yucheng

2017-07-01

Identification of the upstream regulators of a gene is important to characterize the transcriptional pathway and the function of the gene. Previously, we found that a zinc finger protein (ThZFP1) is involved in abiotic stress tolerance of Tamarix hispida. In the present study, we further investigated the transcriptional pathway of ThZFP1. Dof motifs are abundant in the ThZFP1 promoter; therefore, we used them to screen for transcriptional regulators of ThZFP1. A Dof protein, ThDof1.4, binds to the Dof motif specifically, and was hypothesized as the upstream regulator of ThZFP1. Further study showed that overexpression of ThDof1.4 in T. hispida activated the expression of GUS controlled by the ThZFP1 promoter. In T. hispida, transient overexpression of ThDof1.4 increased the transcripts of ThZFP1; conversely, transient RNAi-silencing of ThDof1.4 reduced the expression of ThZFP1. Chromatin immunoprecipitation indicated that ThDof1.4 binds to the ThZFP1 promoter. Additionally, ThDof1.4 and ThZFP1 share similar expression patterns in response to salt or drought stress. Furthermore, like ThZFP1, ThDof1.4 could increase the proline level and enhance ROS scavenging capability to improve salt and osmotic stress tolerance. Together, these results suggested that ThDof1.4 and ThZFP1 form a transcriptional regulatory cascade involved in abiotic stress resistance in T. hispida.

8th International Workshop on Natural Computing

CERN Document Server

Hagiya, Masami

2016-01-01

This book highlights recent advances in natural computing, including biology and its theory, bio-inspired computing, computational aesthetics, computational models and theories, computing with natural media, philosophy of natural computing, and educational technology. It presents extended versions of the best papers selected from the “8th International Workshop on Natural Computing” (IWNC8), a symposium held in Hiroshima, Japan, in 2014. The target audience is not limited to researchers working in natural computing but also includes those active in biological engineering, fine/media art design, aesthetics, and philosophy.

4th International Conference in Network Analysis

CERN Document Server

Koldanov, Petr; Pardalos, Panos

2016-01-01

The contributions in this volume cover a broad range of topics including maximum cliques, graph coloring, data mining, brain networks, Steiner forest, logistic and supply chain networks. Network algorithms and their applications to market graphs, manufacturing problems, internet networks and social networks are highlighted. The "Fourth International Conference in Network Analysis," held at the Higher School of Economics, Nizhny Novgorod in May 2014, initiated joint research between scientists, engineers and researchers from academia, industry and government; the major results of conference participants have been reviewed and collected in this Work. Researchers and students in mathematics, economics, statistics, computer science and engineering will find this collection a valuable resource filled with the latest research in network analysis.

Advances in Computer Entertainment. 10th International Conference, ACE 2013

NARCIS (Netherlands)

Reidsma, Dennis; Katayose, H.; Nijholt, Antinus; Unknown, [Unknown

2013-01-01

These are the proceedings of the 10th International Conference on Advances in Computer Entertainment (ACE 2013), hosted by the Human Media Interaction research group of the Centre for Telematics and Information Technology at the University of Twente, The Netherlands. The ACE series of conferences,

Proceedings of the 10th International Symposium on Laser Spectroscopy

International Nuclear Information System (INIS)

2002-01-01

This proceedings contains articles of the 10th International Symposium on Laser Spectroscopy. It was held on 1-2 Nov 2002 in Taejeon, Korea. The main topics are as follows: Laser Isotope, Laser Spectroscopy, Laser Fusion, Laser Applications and so on. (Yi, J. H.)

Proceedings of the 9th International Symposium on Laser Spectroscopy

International Nuclear Information System (INIS)

2001-11-01

This proceedings contains articles of the 9th International Symposium on Laser Spectroscopy. It was held on 2-3 Nov 2001 in Taejeon, Korea. The main topics are as follows: Laser Isotope, Laser Spectroscopy, Laser Fusion, Laser Applications and so on. (Yi, J. H.)

Proceedings of the 11th International Symposium on Laser Spectroscopy

International Nuclear Information System (INIS)

2003-11-01

This proceedings contains articles of the 11th International Symposium on Laser Spectroscopy. It was held on 7-8 Nov 2003 in Taejeon, Korea. The main topics are as follows: Laser Isotope, Laser Spectroscopy, Laser Fusion, Laser Applications and so on. (Yi, J. H.)

Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM).

Science.gov (United States)

Delmotte, Philippe; Sieck, Gary C

2015-02-01

Airway inflammation is a key aspect of diseases such as asthma. Several inflammatory cytokines (e.g., TNFα and IL-13) increase cytosolic Ca(2+) ([Ca(2+)]cyt) responses to agonist stimulation and Ca(2+) sensitivity of force generation, thereby enhancing airway smooth muscle (ASM) contractility (hyper-reactive state). Inflammation also induces ASM proliferation and remodeling (synthetic state). In normal ASM, the transient elevation of [Ca(2+)]cyt induced by agonists leads to a transient increase in mitochondrial Ca(2+) ([Ca(2+)]mito) that may be important in matching ATP production with ATP consumption. In human ASM (hASM) exposed to TNFα and IL-13, the transient increase in [Ca(2+)]mito is blunted despite enhanced [Ca(2+)]cyt responses. We also found that TNFα and IL-13 induce reactive oxidant species (ROS) formation and endoplasmic/sarcoplasmic reticulum (ER/SR) stress (unfolded protein response) in hASM. ER/SR stress in hASM is associated with disruption of mitochondrial coupling with the ER/SR membrane, which relates to reduced mitofusin 2 (Mfn2) expression. Thus, in hASM it appears that TNFα and IL-13 result in ROS formation leading to ER/SR stress, reduced Mfn2 expression, disruption of mitochondrion-ER/SR coupling, decreased mitochondrial Ca(2+) buffering, mitochondrial fragmentation, and increased cell proliferation.

Understanding the Long-Term Spectral Variability of Cygnus X-1 from BATSE and ASM Observations

Science.gov (United States)

Zdziarski, Andrzej A.; Poutanen, Juri; Paciesas, William S.; Wen, Linqing; Six, N. Frank (Technical Monitor)

2002-01-01

We present a spectral analysis of observations of Cygnus X-1 by the RXTE/ASM (1.5-12 keV) and CGRO/BATSE (20-300 keV), including about 1200 days of simultaneous data. We find a number of correlations between intensities and hardnesses in different energy bands from 1.5 keV to 300 keV. In the hard (low) spectral state, there is a negative correlation between the ASM 1.5-12 keV flux and the hardness at any energy. In the soft (high) spectral state, the ASM flux is positively correlated with the ASM hardness (as previously reported) but uncorrelated with the BATSE hardness. In both spectral states, the BATSE hardness correlates with the flux above 100 keV, while it shows no correlation with the flux in the 20-100 keV range. At the same time, there is clear correlation between the BATSE fluxes below and above 100 keV. In the hard state, most of the variability can be explained by softening the overall spectrum with a pivot at approximately 50 keV. The observations show that there has to be another, independent variability pattern of lower amplitude where the spectral shape does not change when the luminosity changes. In the soft state, the variability is mostly caused by a variable hard (Comptonized) spectral component of a constant shape superimposed on a constant soft blackbody component. These variability patterns are in agreement with the dependence of the rms variability on the photon energy in the two states. We interpret the observed correlations in terms of theoretical Comptonization models. In the hard state, the variability appears to be driven mostly by changing flux in seed photons Comptonized in a hot thermal plasma cloud with an approximately constant power supply. In the soft state, the variability is consistent with flares of hybrid, thermal/nonthermal, plasma with variable power above a stable cold disk. Also, based on broadband pointed observations simultaneous with those of the ASM and BATSE, we find the intrinsic bolometric luminosity increases by a

4th Generation District Heating (4GDH)

DEFF Research Database (Denmark)

Lund, Henrik; Werner, Sven; Wiltshire, Robin

2014-01-01

This paper defines the concept of 4th Generation District Heating (4GDH) including the relations to District Cooling and the concepts of smart energy and smart thermal grids. The motive is to identify the future challenges of reaching a future renewable non-fossil heat supply as part...... of the implementation of overall sustainable energy systems. The basic assumption is that district heating and cooling has an important role to play in future sustainable energy systems – including 100 percent renewable energy systems – but the present generation of district heating and cooling technologies will have...

Proceedings of the 5th International Workshop on Constraints and Language Processing (CSLP 2008)

DEFF Research Database (Denmark)

This research report constitutes the proceedings of the 5th International Workshop on Constraints and Language Processing (CSLP 2008) which is part of the European Summer School in Logic, Language, and Information (ESSLLI 2008), Hamburg, Germany, August 2008.......This research report constitutes the proceedings of the 5th International Workshop on Constraints and Language Processing (CSLP 2008) which is part of the European Summer School in Logic, Language, and Information (ESSLLI 2008), Hamburg, Germany, August 2008....

Editorial. Special issue of Classical and Quantum Gravity on the proceedings of the 4th international LISA symposium

International Nuclear Information System (INIS)

Finn, Lee Samuel

2003-01-01

The 4th International LISA Symposium was held at the National Science Foundation Physics Frontier Center for Gravitational Wave Physics at The Pennsylvania State University on 19-24 July 2002. This special issue of Classical and Quantum Gravity is the proceedings of this meeting. LISA - the Laser Interferometer Space Antenna - is part of an international effort to open a new window on the universe. Not all things radiate light, but everything gravitates. Observations of the gravitational waves radiated by black holes and compact binary star systems, in our galaxy and beyond, can reveal details about these systems and their environments that are otherwise inaccessible. The international effort, of which LISA is a part, includes ground-based detectors, and the relationship between LISA and its ground-based detector 'cousins' was an important theme for this Symposium. LISA will observe gravitational waves in the 0.1 mHz to 0.1 Hz band, complementing observations made by ground-based detectors in the 10 Hz to several KHz band. Together they will explore nearly six decades of bandwidth in the gravitational-wave sky. LISA in particular will observe the gravitational waves radiated by the coalescence of black holes at the centres of colliding galaxies, and the inspiral of compact neutron stars or stellar-mass black holes onto these black holes, virtually anywhere in the universe. It will take a census of neutron star or close white dwarf binaries in our own galaxy and observe the formation of large black holes from the very first structures to form and collapse in our universe. In doing all these things, it will shed new 'light' on the first structures to form in the universe, explore the evolution of galaxies and the roles that black holes play in their structure, test relativity near the 'edges' of a black hole, and deepen our understanding of stellar and binary system evolution. A successful conference - and this LISA Symposium, like its predecessors, was very

20th International Conference on Difference Equations and Applications

CERN Document Server

Ding, Yiming; Došlý, Ondřej

2015-01-01

These proceedings of the 20th International Conference on Difference Equations and Applications cover the areas of difference equations, discrete dynamical systems, fractal geometry, difference equations and biomedical models, and discrete models in the natural sciences, social sciences and engineering. The conference was held at the Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences (Hubei, China), under the auspices of the International Society of Difference Equations (ISDE) in July 2014. Its purpose was to bring together renowned researchers working actively in the respective fields, to discuss the latest developments, and to promote international cooperation on the theory and applications of difference equations. This book will appeal to researchers and scientists working in the fields of difference equations, discrete dynamical systems and their applications.

10th International Conference on Genetic and Evolutionary Computing

CERN Document Server

Lin, Jerry; Wang, Chia-Hung; Jiang, Xin

2017-01-01

This book gathers papers presented at the 10th International Conference on Genetic and Evolutionary Computing (ICGEC 2016). The conference was co-sponsored by Springer, Fujian University of Technology in China, the University of Computer Studies in Yangon, University of Miyazaki in Japan, National Kaohsiung University of Applied Sciences in Taiwan, Taiwan Association for Web Intelligence Consortium, and VSB-Technical University of Ostrava, Czech Republic. The ICGEC 2016, which was held from November 7 to 9, 2016 in Fuzhou City, China, was intended as an international forum for researchers and professionals in all areas of genetic and evolutionary computing.

Roles of the Outer Membrane Protein AsmA of Salmonella enterica in the Control of marRAB Expression and Invasion of Epithelial Cells▿

OpenAIRE

Prieto, Ana I.; Hernández, Sara B.; Cota, Ignacio; Pucciarelli, M. Graciela; Orlov, Yuri; Ramos-Morales, Francisco; García-del Portillo, Francisco; Casadesús, Josep

2009-01-01

A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in phoP and wec mutants of S. enterica and increased the MIC of sodium deoxycholate for the parental strain ATCC 14028. Increased levels of marA mRNA were found in asmA, asmA dam, asmA phoP, and asmA wec strains of S....

Book of abstracts: 3rd International Conference on Smart Energy Systems and 4th Generation District Heating

DEFF Research Database (Denmark)

This year the conference is organised by two research centres/projects in collaboration with Aalborg University. The first is the 4DH Strategic Research Centre and the other is the project RE-INVEST, both supported financial by the Danish Innovation Fund. After the previous two year´s success...... everyone for your valuable contributions. The aim is to present and discuss scientific findings and industrial experiences related to the development of Smart Energy Systems and future 4th Generation District Heating Technologies and Systems (4GDH). This development is fundamental to the implementation...

6th International Conference on Innovations in Bio-Inspired Computing and Applications

CERN Document Server

Abraham, Ajith; Krömer, Pavel; Pant, Millie; Muda, Azah

2016-01-01

This Volume contains the papers presented during the 6th International Conference on Innovations in Bio-Inspired Computing and Applications IBICA 2015 which was held in Kochi, India during December 16-18, 2015. The 51 papers presented in this Volume were carefully reviewed and selected. The 6th International Conference IBICA 2015 has been organized to discuss the state-of-the-art as well as to address various issues in the growing research field of Bio-inspired Computing which is currently one of the most exciting research areas, and is continuously demonstrating exceptional strength in solving complex real life problems. The Volume will be a valuable reference to researchers, students and practitioners in the computational intelligence field.

15th International Conference on Thermal Conductivity

CERN Document Server

1978-01-01

Once again, it gives me a great pleasure to pen the Foreword to the Proceedings of the 15th International Conference on Thermal Conductivity. As in the past, these now biannual conferences pro­ vide a broadly based forum for those researchers actively working on this important property of matter to convene on a regular basis to exchange their experiences and report their findings. As it is apparent from the Table of Contents, the 15th Conference represents perhaps the broadest coverage of subject areas to date. This is indicative of the times as the boundaries between disciplines be­ come increasingly diffused. I am sure the time has come when Con­ ference Chairmen in coming years will be soliciting contributions not only in the physical sciences and engineering', but will actively seek contributions from the earth sciences and life sciences as well. Indeed, the thermal conductivity and related properties of geological and biological materials are becoming of increasing im­ portance to our way of life. As...

7th IEEE International Conference Intelligent Systems

CERN Document Server

Atanassov, KT; Doukovska, L; Hadjiski, M; Jotsov, V; Kacprzyk, J; Kasabov, N; Sotirov, S; Szmidt, E; Zadrożny, S; Filev, D; Jabłkowski, J; Kacprzyk, J; Krawczak, M; Popchev, I; Rutkowski, L; Sgurev, V; Sotirova, E; Szynkarczyk, P

2015-01-01

This two volume set of books constitutes the proceedings of the 2014  7th IEEE International Conference Intelligent Systems (IS), or IEEE IS’2014 for short, held on September 24‐26, 2014 in Warsaw, Poland. Moreover, it contains some selected papers from the collocated IWIFSGN'2014-Thirteenth International Workshop on Intuitionistic Fuzzy Sets and Generalized Nets.The conference was organized by the Systems Research Institute, Polish Academy of Sciences, Department IV of Engineering Sciences, Polish Academy of Sciences, and Industrial Institute of Automation and Measurements - PIAP.The papers included in the two proceedings volumes have been subject to a thorough review process by three highly qualified peer reviewers.Comments and suggestions from them have considerable helped improve the quality of the papers but also the division of the volumes into parts, and assignment of the papers to the best suited parts.  

Towards a Net Zero Building Cluster Energy Systems Analysis for a Brigade Combat Team Complex

Science.gov (United States)

2010-05-01

of technologies, like cogeneration or combined heat and power, waste heat recovery, biomass, geother- mal energy , solar heating (and cooling), and...financial evaluation of all projects. The costs of natural gas, alternative energy technology, alter- native fuels and the impact of greenhouse gas...distribution is unlimited. 1 Proceedings of ASME 2010 4th International Conference on Energy Sustainability ES2010 May 17-22, 2010 Phoenix

4th International Conference on Quantitative Logic and Soft Computing

CERN Document Server

Chen, Shui-Li; Wang, San-Min; Li, Yong-Ming

2017-01-01

This book is the proceedings of the Fourth International Conference on Quantitative Logic and Soft Computing (QLSC2016) held 14-17, October, 2016 in Zhejiang Sci-Tech University, Hangzhou, China. It includes 61 papers, of which 5 are plenary talks( 3 abstracts and 2 full length talks). QLSC2016 was the fourth in a series of conferences on Quantitative Logic and Soft Computing. This conference was a major symposium for scientists, engineers and practitioners to present their updated results, ideas, developments and applications in all areas of quantitative logic and soft computing. The book aims to strengthen relations between industry research laboratories and universities in fields such as quantitative logic and soft computing worldwide as follows: (1) Quantitative Logic and Uncertainty Logic; (2) Automata and Quantification of Software; (3) Fuzzy Connectives and Fuzzy Reasoning; (4) Fuzzy Logical Algebras; (5) Artificial Intelligence and Soft Computing; (6) Fuzzy Sets Theory and Applications.

Assessment of an Engineering Technology Outreach Program for 4th-7th Grade Girls

Science.gov (United States)

Dell, Elizabeth M.; Christman, Jeanne; Garrick, Robert D.

2011-01-01

This paper describes a workshop led by female Engineering Technology students, with support from female faculty, to provide an introduction to Engineering Technology to 4th-7th grade girls through a series of interactive laboratory experiments. This outreach program was developed to improve attitudes towards science and engineering in middle…

Technical justification for ASME code section xi crack detection by visual examination

International Nuclear Information System (INIS)

Nickell, R.E.; Rashid, Y.R.

2001-01-01

A critical technical element of nuclear power plant license renewal in the United States is the demonstration that the effects of aging do not compromise the intended safety function(s) of a system, structure, or component during the extended term of operation. The demonstration may take either of two forms. First, it can be shown that the design basis for the system, structure, or component is sufficiently robust that the aging effects have been insignificant through the current license term, and will continue to be insignificant through the extended term. Alternatively, it can be shown that, while the aging effects may be potentially significant, those effects can be managed and functionality maintained by defined programmatic activities during the extended term of operation. The first of the two approaches is generally provided by the construction basis, such as construction in accordance with the ASME Code Section III and other consensus codes and standards. The second of the two approaches is often provided by periodic inservice inspection and testing, in accordance with the ASME Code Section XI. The purpose of the ASME Section XI inspections and tests is to assure that systems, components, and structures are fit for continued service until the next scheduled inspection or test. The purpose of this paper is to document the effectiveness of the current ASME Code Section XI visual examination procedures in detecting the effects of aging for systems, structures, and components that are tolerant of mature cracks. (author)

10th International Conference Mechatronics

CERN Document Server

Jabloński, Ryszard

2014-01-01

Mechatronics, as the integrating framework of mechanical engineering, electrical engineering, computer technology, control engineering and automation forms a crucial part in the design, manufacture and maintenance of a wide range of engineering products and processes. The mechatronics itself changes rapidly in last decade, from original mixture of subfields into original approach in engineering as a technical discipline. The book you are holding is aimed to help the reader to orient in this evolving field of science and technology. „Mechatronics 2013: Recent Technological and Scientific Advances“ is the fourth volume following the previous editions in 2007, 2009 and 2011, providing the comprehensive and accessible coverage of advances in mechatronics presented on the 10th International Conference Mechatronics 2013, hosted this year at the Brno University of Technology, Czech Republic. The contributions, that passed the thorough review process, give an insight into current trends in research and developmen...

11th KES International Conference

CERN Document Server

Kusek, Mario; Chen-Burger, Yun-Heh; Howlett, Robert; Jain, Lakhmi

2017-01-01

This volume highlights new trends and challenges in research on agents and the new digital and knowledge economy, and includes 23 papers classified into the following categories: business process management, agent-based modeling and simulation, and anthropic-oriented computing. All papers were originally presented at the 11th International KES Conference on Agents and Multi-Agent Systems – Technologies and Applications (KES-AMSTA 2017) held June 21–23, 2017 in Vilamoura, Algarve, Portugal. Today’s economy is driven by technologies and knowledge. Digital technologies can free, shift and multiply choices, and often intrude on the territory of other industries by providing new ways of conducting business operations and creating value for customers and companies. The topics covered in this volume include software agents, multi-agent systems, agent modeling, mobile and cloud computing, big data analysis, business intelligence, artificial intelligence, social systems, computer embedded systems and nature insp...

15th International Conference on Biomedical Engineering

CERN Document Server

2014-01-01

This volume presents the proceedings of the 15th ICMBE held from 4th to 7th December 2013, Singapore. Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health records to diagnostic tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers is evident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineers would use principles from applied science including mechanical, electrical, chemical and computer engineering together with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine. Applying such concepts to the human body is very much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality of healthcare. With this understanding, the conference proceedings offer a single platform for individuals and organisations working i...

Proceedings of the 20th International Meshing Roundtable

CERN Document Server

2012-01-01

This volume contains the articles presented at the 20th International Meshing Roundtable (IMR) organized, in part, by Sandia National Laboratories and was held in Paris, France on Oct 23-26, 2011. This is the first year the IMR was held outside the United States territory. Other sponsors of the 20th IMR are Systematic Paris Region Systems & ICT Cluster, AIAA, NAFEMS, CEA, and NSF. The Sandia National Laboratories started the first IMR in 1992, and the conference has been held annually since. Each year the IMR brings together researchers, developers, and application experts, from a variety of disciplines, to present and discuss ideas on mesh generation and related topics. The topics covered by the IMR have applications in numerical analysis, computational geometry, computer graphics, as well as other areas, and the presentations describe novel work ranging from theory to application.     .

10th International Workshop on Condensed Matter Theories

CERN Document Server

Kalia, Rajiv; Bishop, R

1987-01-01

The second volume of Condensed Matter Theories contains the proceedings of the 10th International Workshop held at Argonne National Laboratory, Argonne, IL, U.S.A. during the week of July 21, 1986. The workshop was attended by high-energy, nuclear and condensed-matter physicists as well as materials scientists. This diverse blend of participants was in keeping with the flavor of the previous workshops. This annual series of international workshops was"started in 1977 in Sao Paulo, Brazil. Subsequent'workshops were held in Trieste (Italy), Buenos Aires (Argentina), Caracas (Venezuela), Altenberg (West Germany), Granada (Spain), and San Francisco (U.S.A.). What began as a meeting of the physicists from the Western Hemisphere has expanded in the last three years into an international conference of scientists with diverse interests and backgrounds. This diversity has promoted a healthy exchange of ideas from different branches of physics and also fruitful interactions among the participants. The present volume is...

ASME and RCC-MR comparison for the prevention of fatigue analysis

International Nuclear Information System (INIS)

Autrusson, B.; Acker, D.

1989-01-01

The purpose of this survey is to compare the simplified methods, without reference to the safety factor allowed for the mechanical properties. An application of both codes, RCC-MR and ASME, on the design of the wall mock-up of the NET project is made and also an estimation with an elastoplastic analysis. In the case of fatigue analysis according to ASME in the plastic field, the elastic stress is magnified by a K e factor derived from stress variation, S n , disregarding geometrical discontinuities. According to RCC-MR, the elastic maximum strain will magnified by two coefficients accounting for plasticity and variation of Poisson ratio

THE 4th SCHIZOPHRENIA INTERNATIONAL RESEARCH SOCIETY CONFERENCE, 5–9 APRIL 2014, FLORENCE, ITALY: A summary of topics and trends

Science.gov (United States)

Abayomi, Olukayode; Amato, Davide; Bailey, Candace; Bitanihirwe, Byron; Bowen, Lynneice; Burshtein, Shimon; Cullen, Alexis; Fusté, Montserrat; Herrmann, Ana P; Khodaie, Babak; Kilian, Sanja; Lang, Qortni A; Manning, Elizabeth E; Massuda, Raffael; Nurjono, Milawaty; Sadiq, Sarosh; Sanchez-Gutierrez, Teresa; Sheinbaum, Tamara; Shivakumar, Venkataram; Simon, Nicholas; Spiteri-Staines, Anneliese; Sirijit, Suttajit; Toftdahl, Nanna Gilliam; Wadehra, Sunali; Wang, Yi; Wigton, Rebekah; Wright, Susan; Yagoda, Sergey; Zaytseva, Yuliya; O’Shea, Anne; DeLisi, Lynn E.

2015-01-01

The 4th Schizophrenia International Research Society Conference was held in Florence, Italy, April 5–9, 2014.and this year had as its emphasis, “Fostering Collaboration in Schizophrenia Research”. Student travel awardees served as rapporteurs for each oral session, summarized the important contributions of each session and then each report was integrated into a final summary of data discussed at the entire conference by topic. It is hoped that by combining data from different presentations, patterns of interest will emerge and thus lead to new progress for the future. In addition, the following report provides an overview of the conference for those who were present, but could not participate in all sessions, and those who did not have the opportunity to attend, but who would be interested in an update on current investigations ongoing in the field of schizophrenia research. PMID:25306204

77 FR 19646 - International Whaling Commission; 64th Annual Meeting; Nominations

Science.gov (United States)

2012-04-02

... Commissioner representing the positions of non-governmental organizations. Generally, only one non-governmental... the U.S. IWC Commissioner representing the positions of non-governmental organizations. Generally... International Whaling Commission; 64th Annual Meeting; Nominations AGENCY: National Marine Fisheries Service...

6th International Parallel Tools Workshop

CERN Document Server

Brinkmann, Steffen; Gracia, José; Resch, Michael; Nagel, Wolfgang

2013-01-01

The latest advances in the High Performance Computing hardware have significantly raised the level of available compute performance. At the same time, the growing hardware capabilities of modern supercomputing architectures have caused an increasing complexity of the parallel application development. Despite numerous efforts to improve and simplify parallel programming, there is still a lot of manual debugging and  tuning work required. This process  is supported by special software tools, facilitating debugging, performance analysis, and optimization and thus  making a major contribution to the development of  robust and efficient parallel software. This book introduces a selection of the tools, which were presented and discussed at the 6th International Parallel Tools Workshop, held in Stuttgart, Germany, 25-26 September 2012.

5th International Congress on Energy Fluxes and Radiation Effects 2016

International Nuclear Information System (INIS)

2017-01-01

Special Issue of the Materials of the V International Congress on Energy Fluxes and Radiation Effects (Tomsk, Russia, 2016)Maksim Trigub, Georgiy Osokin, Alexander KonovodNational Research Tomsk Polytechnic University, 30, Lenin Avenue, Tomsk, Russiaemail: geosokin@tpu.ruThe present issue of the journal is based on the materials of the V International Congress on Energy Fluxes and Radiation Effects 2016 (EFRE 2016) that was held on October 2 to 7, 2016 in Tomsk (Russia). This large scientific forum gathers together scientists, developers and representatives of knowledge-intensive enterprises that have relevance to physics and technology. This year, the Congress was dedicated to the 120 th anniversary of the National Research Tomsk Polytechnic University.The history of the Congress as a joint scientific event dates back to 2000; it traditionally includes three conferences: International Symposium on High-Current Electronics (SHCE), International Conference on Radiation Physics and Chemistry of Condensed Matter (RPC) and International Conference on Modification of Materials with Particle Beams and Plasma Flows (CMM). However, each of these large conferences has its own lasting history.In 2016, the International Symposium on High-Current Electronics was arranged for the 19 th time. The participants have presented the results of fundamental studies and applied outcomes in the fields of high-power pulsed energy engineering and electronics (Pulsed Power), physics and application of high-power electron and ion beams, high- and low-temperature gas discharge plasma, physics of high-energy treatment and extreme states of matter, electric pulsed technologies. Noteworthy, the symposium took place in the year of the 40 th anniversary of USSR scientific discovery of explosive electron emission. This physical phenomenon—being one of the basics of high-current electronics—determines the processes in pulsed vacuum discharge, enables the operation of high-current electron

Distributed Autonomous Robotic Systems : the 12th International Symposium

CERN Document Server

Cho, Young-Jo

2016-01-01

This volume of proceedings includes 32 original contributions presented at the 12th International Symposium on Distributed Autonomous Robotic Systems (DARS 2014), held in November 2014. The selected papers in this volume are authored by leading researchers from Asia, Europe, and the Americas, thereby providing a broad coverage and perspective of the state-of-the-art technologies, algorithms, system architectures, and applications in distributed robotic systems. .

Proceeding of the 5th international workshop on reflectometry

International Nuclear Information System (INIS)

Kawahata, Kazuo

2001-05-01

This is the proceedings of the 5th International Workshop on Reflectometry, which was held on 5-7 March, 2001, at the National Institute for Fusion Science. In this workshop, the latest experimental results in reflectometry (profile and fluctuations studies), new technological developments and a broad scope of the theory and simulation codes were presented. The 19 of the presented papers are indexed individually. (author)

Application of the ASME code in the design of the GA-4 and GA-9 casks

International Nuclear Information System (INIS)

Mings, W.J.; Koploy, M.A.

1992-01-01

General Atomics (GA) is developing two spent fuel shipping casks for transport by legal weight truck (LWT). The casks are designed to the loading, environmental conditions and safety requirements defined in Title 10 of the Code of Federal Regulations, Part 71 (10CFR71). To ensure that all components of the cask meet the 10CFR71 rules, GA established structural design criteria for each component based on NRC Regulatory Guides and the American Society of Mechanical Engineers Boiler and Pressure Vessel Code (ASME Code). This paper discusses the criteria used for different cask components, how they were applied and the conservatism and safety margins built into the criteria and assumption

The 14th international workshop on wave hindcasting and forecasting and the 5th coastal hazards symposium

Science.gov (United States)

Breivik, Øyvind; Alves, Jose Henrique; Greenslade, Diana; Horsburgh, Kevin; Swail, Val

2017-04-01

Following the 14th International Workshop on Wave Hindcasting and Forecasting and 5th Coastal Hazards Symposium in November 2014 in Key West, Florida, a topical collection has appeared in recent issues of Ocean Dynamics. Here, we give a brief overview of the 16 papers published in this topical collection as well as an overview of the widening scope of the conference in recent years. A general trend in the field has been towards closer integration between the wave and ocean modelling communities. This is also seen in this topical collection, with several papers exploring the interaction between surface waves and mixed layer dynamics and sea ice.

6th International Symposium on Thermal Expansion

CERN Document Server

1978-01-01

This 6th International Symposium on Thermal Expansion, the first outside the USA, was held on August 29-31, 1977 at the Gull Harbour Resort on Hecla Island, Manitoba, Canada. Symposium Chairman was Ian D. Peggs, Atomic Energy of Canada Limited, and our continuing sponsor was CINDAS/Purdue University. We made considerable efforts to broaden the base this year to include more users of expansion data but with little success. We were successful, however, in establishing a session on liquids, an area which is receiving more attention as a logical extension to the high-speed thermophysical property measurements on materials at temperatures close to their melting points. The Symposium had good international representation but the overall attendance was, disappointingly, relatively low. Neverthe­ less, this enhanced the informal atmosphere throughout the meeting with a resultant frank exchange of information and ideas which all attendees appreciated. A totally new item this year was the presentation of a bursary to ...

Función adrenal y metabolismo lipídico en niños asmáticos tratados con budesonida

Directory of Open Access Journals (Sweden)

Paoli-de Valeri Mariela

1999-01-01

Full Text Available Objetivo. Evaluar el efecto de bajas dosis de budesonida inhalado sobre la función adrenal y el metabolismo lipídico en niños asmáticos. Material y métodos. Se estudiaron: 10 niños asmáticos (edad promedio, 8.6 años tratados con budesonida inhalado (200-300 µg/día por un lapso mayor a tres meses (grupo A; 15 niños asmáticos (edad promedio, 7.8 años sin tratamiento esteroideo (grupo B, y 10 niños no asmáticos (grupo C. Se determinaron los niveles de cortisol basal y postestímulo con ACTH, andrógenos adrenales, lípidos y cortisol urinario. Resultados. Entre los grupos A y B no hubo diferencias significativas en las variables estudiadas. En los niños asmáticos (grupo A-B el cortisol urinario fue significativamente mayor en relación con el grupo C. Los niveles de triglicéridos, colesterol total, colesterol de la lipoproteína de baja densidad e índices aterogénicos fueron mayores en el grupo de niños asmáticos, con y sin budesonida, comparados con el grupo C. Conclusiones. El tratamiento con dosis bajas de budesonida inhalado en niños asmáticos no modificó la función del eje adrenal ni el metabolismo lipídico. Los pacientes asmáticos presentaron un perfil lipídico aterogénico que podría incrementar el riesgo de enfermedad cardiovascular.

Bibliometric Analyses Reveal Patterns of Collaboration between ASMS Members

Science.gov (United States)

Palmblad, Magnus; van Eck, Nees Jan

2018-03-01

We have explored the collaborative network of the current American Society for Mass Spectrometry (ASMS) membership using bibliometric methods. The analysis shows that 4249 members are connected in a single, large, co-authorship graph, including the majority of the most published authors in the field of mass spectrometry. The map reveals topographical differences between university groups and national laboratories, and that the co-authors with the strongest links have long worked together at the same location. We have collected and summarized information on the geographical distribution of members, showing a high coverage of active researchers in North America and Western Europe. Looking at research fields, we could also identify a number of new or `hot' topics among ASMS members. Interactive versions of the maps are available on-line at https://goo.gl/UBNFMQ (collaborative network) and https://goo.gl/WV25vm (research topics). [Figure not available: see fulltext.

12th International Conference on Multiple Criteria Decision Making

CERN Document Server

Gal, Tomas

1997-01-01

The organizers of the 12th International Conference on Multiple Cri­ teria Decision Making (MCDM) held June 19-23, 1995 in Hagen received the second time the opportunity to prepare an international conference on MCDM in Germany; the first opportunity has been the 3rd International Conference on MCDM in Konigswinter, 1979. Quite a time ellapsed since then and therefore it might be interesting to compare some indicators of the development of the International Society on MCDM, which has been founded in Konigswinter. Stanley Zionts has been elected first president and all 44 participants of that Conference became founding members. Today our Society has over 1200 members and its own Journal (MCDM World Scan). In Hagen, 1996, we had 152 participants from 34 countries. It is interesting to mention that also other Groups established their organi­ zation, like the European Working Group on Multiple Criteria Decision Aid, the German Working Group on Decision Theory and Applications, the Multi­ Objective Programming ...

The 1997 NRC IST workshops and the status of questions and issues directed to the ASME O and M committee

International Nuclear Information System (INIS)

DiBiasio, A.M.

1998-05-01

This paper describes the results of the four NRC Inservice Testing (IST) Workshops which were held in early 1997 pertaining to NRC Inspection Procedure P 73756, Inservice Testing of Pumps and Valves. It also presents the status of the ASME code committees' resolution of certain questions forwarded to the ASME by the NRC. These questions relate to code interpretations, inconsistencies in the code, and industry concerns that are most appropriately resolved through the ASME consensus process. The ASME committees reviewed the questions at their December 1997 and March 1998 code meetings. Of particular interest are those questions for which the ASME code committees did not agree with the NRC response. These questions, as well as those which the committees provided some additional insight or input, are presented in this paper

A Retrospective Look at 20 Years of ASM Education Programs (1990-2010 and a Prospective Look at the Next 20 Years (2011-2030

Directory of Open Access Journals (Sweden)

Amy Chang

2011-03-01

Full Text Available The Education Board of the American Society for Microbiology (ASM was established in the mid-1970s to address the graduate and medical education needs of ASM members. Since then, I have watched our offerings evolve from a small, graduate-level travel grant program for ASM meetings to a growing suite of professional development and networking opportunities including fellowships, publications, and conferences. Along the way, our audience has expanded from  graduate students to undergraduate biology and K-12 teachers, students of all ages, researchers, and the public.I have been fortunate enough to watch several pivotal programs and projects support our growth and change the status quo by providing opportunities for biology educators to flourish. These include the: (i Coalition for Education in the Life Sciences, (ii ASM Division on Microbiology Education, (iii ASM Conference for Undergraduate Educators, (iv ASM Journal of Microbiology & Biology Education, and (v ASM Fellowship Fund. In this review, the background and details I offer on each initiative help explain ASM Education offerings, how our growth has been supported, and where are we headed.

ROCAM: The 5-th International Edition of Romanian Conference on Advanced Materials. Abstracts

International Nuclear Information System (INIS)

Stanculescu, Florin

2006-01-01

The proceedings of the 5-th International Edition of Romanian Conference on Advanced Materials and Crystal Growth with special topics on nano and multifunctional materials held on September 11-14, 2006 in Bucharest- Magurele, Romania, contains contributions presented as plenary lectures, invited papers and regular contributions in eight sections, namely: 1. Growth and characterization of inorganic crystals; 2. Growth and characterization of organic and biological crystals; 3. Nano and microstructured materials and thin films; 4. Polymers/fuel cells and hydrogen storage; 5. Plasma deposition and applications; 6. Advanced processing and characterization / noncrystalline solids; 7. Advanced nuclear materials; 8. Advanced materials: general aspects

The 11th International ICIT Conference Progress in Cryogenics and Isotopes Separation. Proceedings

International Nuclear Information System (INIS)

Stefanescu, Ioan

2005-01-01

The proceedings of the 11th International ICIT Conference Progress in Cryogenics and Isotopes Separation held in Caciulata, Romania on 12-14 October 2005 contain plenary lectures (6 papers) and 6 sections addressing the following subject matters: Section 1. Stable Isotopes Physics. Technologies and Applications (5 papers); Section 2. Science and Materials Engineering (11 papers); Section 3. Nuclear Power (21 papers); Section 4. Hydrogen and Fuel Cells (7 papers); Section 5. Environmental Protection. Industrial Risk (10 papers); Section 6. Laboratory Analysis Methods (10 papers). Twenty two papers are available in abstract form only and full text entered the corresponding records

4th International Conference on Nonlinear Mechanics

CERN Document Server

Maugin, G

2003-01-01

The mechanics of electromagnetic materials and structures has been developing rapidly with extensive applications in, e. g. , electronics industry, nuclear engineering, and smart materials and structures. Researchers in this interdisciplinary field are with diverse background and motivation. The Symposium on the Mechanics of Electromagnetic Materials and Structures of the Fourth International Conference on Nonlinear Mechanics in Shanghai, China in August 13-16, 2002 provided an opportunity for an intimate gathering of researchers and exchange of ideas. This volume contains papers based on most of the presentations at the symposium, and articles from a few invited contributors. These papers reflect some of the recent activities in the mechanics of electromagnetic materials and structures. The first twelve papers are in the order in which they were listed in the program of the conference. These are followed by six invited papers in alphabetical order of the last names of the first authors. We would like to exte...

12th International Conference on Thalassemia and the Haemoglobinopathies, 11-14 May 2011, Antalya, Turkey

Directory of Open Access Journals (Sweden)

Guest Editors: Aurelio Maggio, Duran Canatan, Androulla Eleftheriou

2011-05-01

Full Text Available This abstract book contains all abstracts presented to the 12th International Conference on Thalassaemia and Other Haemoglobinopathies, and the 14th TIF Conference for Patients and Parents, 11-14 May 2011, Antalya, Turkey.

10th International Conference on Scientific Computing in Electrical Engineering

CERN Document Server

Clemens, Markus; Günther, Michael; Maten, E

2016-01-01

This book is a collection of selected papers presented at the 10th International Conference on Scientific Computing in Electrical Engineering (SCEE), held in Wuppertal, Germany in 2014. The book is divided into five parts, reflecting the main directions of SCEE 2014: 1. Device Modeling, Electric Circuits and Simulation, 2. Computational Electromagnetics, 3. Coupled Problems, 4. Model Order Reduction, and 5. Uncertainty Quantification. Each part starts with a general introduction followed by the actual papers. The aim of the SCEE 2014 conference was to bring together scientists from academia and industry, mathematicians, electrical engineers, computer scientists, and physicists, with the goal of fostering intensive discussions on industrially relevant mathematical problems, with an emphasis on the modeling and numerical simulation of electronic circuits and devices, electromagnetic fields, and coupled problems. The methodological focus was on model order reduction and uncertainty quantification.

Executive summary of the 12th HHT international scientific conference.

Science.gov (United States)

Andrejecsk, Jillian W; Hosman, Anna E; Botella, Luisa M; Shovlin, Claire L; Arthur, Helen M; Dupuis-Girod, Sophie; Buscarini, Elisabetta; Hughes, Christopher C W; Lebrin, Franck; Mummery, Christine L; Post, Marco C; Mager, Johannes J

2018-02-01

Hereditary hemorrhagic telangiectasia is an autosomal dominant trait affecting approximately 1 in 5000 people. A pathogenic DNA sequence variant in the ENG, ACVRL1 or SMAD4 genes, can be found in the majority of patients. The 12th International Scientific HHT Conference was held on June 8-11, 2017 in Dubrovnik, Croatia to present and discuss the latest scientific achievements, and was attended by over 200 scientific and clinical researchers. In total 174 abstracts were accepted of which 58 were selected for oral presentations. This article covers the basic science and clinical talks, and discussions from three theme-based workshops. We focus on significant emergent themes and unanswered questions. Understanding these topics and answering these questions will help to define the future of HHT research and therapeutics, and ultimately bring us closer to a cure.

When international academics in management meet in Hungary: Report on the 5th International Conference on Management

OpenAIRE

Utzeri, Mounia

2015-01-01

The fifth International Conference on Management was held 18-19th of July 2015 in Gödöllö, Hungary. The topics of this conference were built around the contemporary issues in leadership, management and entrepreneurship from an interdisciplinary perspective.

4th Machining Innovations Conference

CERN Document Server

2014-01-01

This contributed volume contains the research results presented at the 4th Machining Innovations Conference, Hannover, September 2013. The topic of the conference are new production technologies in aerospace industry and the focus is on energy efficient machine tools as well as sustainable process planning. The target audience primarily comprises researchers and experts in the field but the book may also be beneficial for graduate students.

The ASME Section 11 Special Working Group On Plant Life Extension

International Nuclear Information System (INIS)

Katz, L.R.

1990-01-01

The codes and standards applicable to plant life extension have not been identified in the U.S. at this time. However, several initiatives have been taken to establish specific codes and standards pertaining to nuclear plant life extension (PLEX). One of these initiatives, sponsored by ASME, is the Section XI Special Working Group on Plant Life Extension (SWG-PLEX). The SWG-PLEX reports to the ASME Section XI Subcommittee and is responsible for recommending or drafting rules and requirements for modifying Section XI to accommodate age-related degradation to support nuclear plant life extension. This paper summarizes the results and reports the activities of the SWG-PLEX during the 1989/1990 period

The 6th International Earth Science Olympiad: A Student Perspective

Science.gov (United States)

Barlett, Luke; Cathro, Darcy; Mellow, Maddi; Tate, Clara

2014-01-01

In October 2012, two students from the Australian Science and Mathematics School and two from Yankalilla Area School were selected to travel to Olavarria, Argentina in order to compete in the 6th International Earth Science Olympiad (IESO). It was an opportunity for individuals with a passion for Earth science to come together from 17 countries to…

Mathematics Anxiety Among 4th And 5th Grade Turkish Elementary School Students

OpenAIRE

Fulya Yüksel-Şahin

2008-01-01

Using a sample of 4th and 5th graders, this study investigated whether students’ mathematics anxiety differed significantly according to a group of variables. A total of 249 students participated in the study. “The Mathematics Anxiety Scale for Elementary School Students” and “The Personal Information Form” were used for data collection. Independent samples t-tests, Oneway Anova and Schefee test were used to analyze the data. Results showed that students’ mathematics anxiety differed signific...

Bronchodilatory and anti-inflammatory effects of ASM-024, a nicotinic receptor ligand, developed for the treatment of asthma.

Science.gov (United States)

Assayag, Evelyne Israël; Beaulieu, Marie-Josée; Cormier, Yvon

2014-01-01

Conventional asthma and COPD treatments include the use of bronchodilators, mainly β2-adrenergic agonists, muscarinic receptor antagonists and corticosteroids or leukotriene antagonists as anti-inflammatory agents. These active drugs are administered either separately or given as a fixed-dose combination medication into a single inhaler. ASM-024, a homopiperazinium compound, derived from the structural modification of diphenylmethylpiperazinium (DMPP), has been developed to offer an alternative mechanism of action that could provide symptomatic control through combined anti-inflammatory and bronchodilator properties in a single entity. A dose-dependent inhibition of cellular inflammation in bronchoalveolar lavage fluid was observed in ovalbumin-sensitized mice, subsequently treated for 3 days by nose-only exposure with aerosolized ASM-024 at doses up to 3.8 mg/kg (ED50 = 0.03 mg/kg). The methacholine ED250 values indicated that airway hyperresponsivenness (AHR) to methacholine decreased following ASM-024 administration by inhalation at a dose of 1.5 mg/kg, with a value of 0.145 ± 0.032 mg/kg for ASM 024-treated group as compared to 0.088 ± 0.023 mg/kg for untreated mice. In in vitro isometric studies, ASM-024 elicited dose-dependent relaxation of isolated mouse tracheal, human, and dog bronchial preparations contracted with methacholine and guinea pig tracheas contracted with histamine. ASM-024 showed also a dose and time dependant protective effect on methacholine-induced contraction. Overall, with its combined anti-inflammatory, bronchodilating and bronchoprotective properties, ASM-024 may represent a new class of drugs with a novel pharmacological approach that could prove useful for the chronic maintenance treatment of asthma and, possibly, COPD.

4th International Bulgarian Forum “Origins, Historical Development and Cultural Heritage of Bulgarian Civilization” (Varna, Bulgaria, 22-25 October 2012

Directory of Open Access Journals (Sweden)

Khuzin Fayaz Sh.

2013-03-01

Full Text Available The work of the 4th International forum "Origins, historical development and cultural heritage of Bulgarian civilization" is highlighted in the article. The forum was organized by the Tatarstan Republican Fund "Vozrozhdenie", Ministries of Culture of the Republic of Bulgaria and the Republic of Tatarstan, the National Archaeological Institute and Museum with the Bulgarian Academy of Sciences, Institute of History named after S. Mardjani, Academy of Sciences of the Republic of Tatarstan, and Varna Regional Historical Museum. It was attended by more than 100 scholars from different research centers of Bulgaria, Russia, Ukraine, Romania, Hungary, and Switzerland. They discussed issues related to the ethnogenesis, ancient and medieval history of the peoples whose origin is connected with the history of the Bulgarians and their state, questions of mutual influence in the field of culture between the Bulgarians and the neighboring peoples, as well as actual problems of cultural heritage study and conservation.

PREFACE: 35th International Symposium on Remote Sensing of Environment (ISRSE35)

Science.gov (United States)

2014-03-01

35th International Symposium on Remote Sensing of Environment (ISRSE35) 22-26 April, 2013, Beijing, China The 35th International Symposium on Remote Sensing of Environment (ISRSE35) was successfully convened in Beijing, China, from April 22nd to 26th, 2013. This was the first event in the ISRSE series being held in China. The symposium was hosted by the Institute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, and co-organized by the International Center for Remote Sensing of Environment (ICRSE), the International Society for Photogrammetry and Remote Sensing (ISPRS), the Group on Earth Observations (GEO), the International Society for Digital Earth (ISDE) and the Chinese Academy of Sciences (CAS). The theme of the symposium was ''Earth Observation and Global Environmental Change''. Back in 1962, the first ISRSE was convened at the University of Michigan, USA. Over the past 50 years, Earth observation has advanced significantly, and remote sensing has become a mature technology for observing the Earth and monitoring global environmental change. At present, remote sensing has already entered an era of integrated, coordinated and sustainable global Earth observation and rapid development of spatial information services. It is very exciting to see that remote sensing technologies have become indispensable tools in numerous fields of Earth systems science, and are playing more and more important roles in areas such as land resources surveying and mapping, crop and forest monitoring, mineral exploration, urban development, ocean and coastlines resources surveillance, and in the monitoring and assessment of floods, droughts, forest fires, landslides and earthquakes. Thus, remote sensing has made great contributions to the socio-economic development of the world and it is anticipated that it will provide more powerful support in advancing the fields of Earth systems science and global change research. The 35th ISRSE was a platform for scientists and

9th International Workshop on the CKM Unitarity Triangle

CERN Document Server

CKM2016

2016-01-01

The 9th International Workshop on the CKM Unitarity Triangle (CKM 2016) will be held during November 28 to December 3, 2016 at the Tata Institute of Fundamental Research in Mumbai, India. The CKM series is a well-established international meeting in the field of quark-flavour physics that brings both experimenters and theorists on a common platform. On the experimental front, we bridge borders between neutron, kaon, charm and beauty hadron, and top quark physics. The theory program tries to cover a wide range of approaches. We shall discuss how this marriage of the two can indirectly probe physics beyond the standard model, taking into account the interplay with high-pT collider searches.

Analysis of the ASME methodology for evaluation of erosion-corrosion defects with respect to the differences in the calculation and in materials used at the Dukovany NPP

International Nuclear Information System (INIS)

Kadecka, P.

1995-01-01

The problem of evaluation of tolerable defects and thinning of pipe walls was analyzed. In fact, a procedure for evaluation of tolerable defects is described in ASME Code Case N 480 based on the ASME ''Rules for Construction of Nuclear Power Plant Components''. The pipe systems of the Dukovany NPP, however, were constructed to different (East European) standards, and therefore caution should be exercised when applying US standards to this plant. The report demonstrates major differences between the ASME Standard and the proposed Czech standard ''A.S.I. Standards Documentation for Strength Calculations of Equipment and Piping of WWER Type Nuclear Power Plants'' developed by the Czech Association of Mechanical Engineers (A.S.I), evaluates the applicability of Code Case N 480 to the Dukovany plant, and proposes a Czech procedure for the evaluation. The basic characteristics of materials cited by ASME II and carbon steels used in the secondary circuit of the Dukovany NPP are also compared. (P.A.). 78 tabs., 2 figs., 4 refs

Proceedings of the 13th international symposium on laser-aided plasma diagnostics

International Nuclear Information System (INIS)

Kawahata, Kazuo

2007-09-01

The 9th international symposium on LASER-AIDED PLASMA DIAGNOSTICS was held from 18th November to 21st September, 2007 at Takayama, Japan. This symposium was organized by the National Institute for Fusion Science, Toki, Japan. The topics of the symposium include laser diagnostics and diagnostics aided by lasers for fusion plasmas, industrial process plasmas, environmental plasmas as well as for other plasma applications and processes related to plasmas. Hardware development related to laser-aided plasma diagnostics is another topic. Over 80 participants attended this international symposium. 1 Akazaki lecture, 10 general talks, 10 topical talks, 12 short oral talks and 45 posters were presented. This issue is the collection of the papers presented at the title symposium. The 41 of the presented papers are indexed individually. (J.P.N.)

4th annual Safety Day: full of colour!

CERN Multimedia

HSE Unit

2014-01-01

On Thursday 10 April, more than 240 people took part in the 4th annual Safety Day, organised on the occasion of the World Day for Safety and Health at Work. The HSE Unit, in partnership with the Fire Brigade (GS/FB) and the TE and BE Departments, organised various stands and activities connected with this year’s theme, chosen by the International Labour Organization: "Safety and health in the use of chemicals at work”.   The stands, set up at lunchtime in all three of CERN’s restaurants as well as in the entrance hall of Building 500, were designed to: Remind visitors of the need to use personal protective equipment appropriate to the chemicals they are using; Make visitors aware of the potential environmental impact of using chemicals; Encourage visitors to always read the labels and safety data sheets of dangerous chemicals and everyday domestic products; Inform visitors that a safety training course called “Chemical Risk Awareness&r...

4th international conference in sustainability in energy and buildings

CERN Document Server

Höjer, Mattias; Howlett, Robert; Jain, Lakhmi

2013-01-01

This volume contains the proceedings of the Fourth International Conference on Sustainability in Energy and Buildings, SEB12, held in Stockholm, Sweden, and is organised by KTH Royal Institute of Technology, Stockholm, Sweden in partnership with KES International. The International Conference on Sustainability in Energy and Buildings focuses on a broad range of topics relating to sustainability in buildings but also encompassing energy sustainability more widely. Following the success of earlier events in the series, the 2012 conference includes the themes Sustainability, Energy, and Buildings and Information and Communication Technology, ICT. The SEB’12 proceedings includes invited participation and paper submissions across a broad range of renewable energy and sustainability-related topics relevant to the main theme of Sustainability in Energy and Buildings. Applicable areas include technology for renewable energy and sustainability in the built environment, optimisation and modeling techniques, informati...

Food Micro 2010, 22th International ICFMH Symposium, “ Microbial Behaviour in the Food Chain ” 30th August – 3rd September 2010, Copenhagen, Denmark

DEFF Research Database (Denmark)

2012-01-01

This Special Issue of International Journal of Food Microbiology contains a selection of papers presented at Food Micro 2010, the 22th Symposium of the International Committee on Food Microbiology and Hygiene (ICFMH). Food Micro 2010 was held on 30th August to 3rd September 2010 in Copenhagen......, Denmark and organized in collaboration between the Danish Centre for Advanced Food Studies (LMC) and Lund University in Sweden....

Creep-fatigue damage evaluation for SS-316LN (ORNL PLATES): - RCC-MR vs. ASME SEC III - NH

International Nuclear Information System (INIS)

Sati, Bhuwan Chandra; Jalaldeen, S.; Velusamy, K.; Selvaraj, P.

2016-01-01

Investigations of high temperature tests done on ORNL plate with deformation control loading, under creep-fatigue damage have been presented. The test results with methodology of RCC-MR and ASME-NH life prediction under creep-fatigue loading have been assessed. The stress relaxation effect in calculating the life using RCC-MR under creep-fatigue damage is found to be significant in presence of secondary stress. RCC-MR: 2007 is more realistic number of cycles (predicts 51 number of cycles) as compared to ASME-NH (predicts 312 number of cycles) which is demonstrated by the experimental work (observed 86 numbers of cycles). Between RCC-MR and experimental work, design code seems to be more conservative for life prediction due to creep-fatigue damage. For fatigue damage, the approaches are same and the difference comes from material properties and the starting stress for applying Neuber's rule. ASME approach has the limitation of stress range magnitude. ASME approach predicts lower elastic plus plastic strain for the cases having S* above the linear stress limit. For creep strain and creep damage evaluation, ASME and RCC-MR have different approaches for calculating the stress at the beginning and during the hold period. The RCC-MR takes account of cyclic hardening or softening effects (hardening in the present case of 316 LN) by means of the cyclic stress-strain curve and the benefit of symmetrization effects which are significant for this material. The ASME code neglects these effects and instead relies on an approach based on the isochronous stress-strain curves. (author)

5th Bionanotox and Applications International Research Conference, Peabody, Little Rock, Arkansas, USA

Science.gov (United States)

Sabb, Taneicie; Chowdhury, Parimal

2011-06-01

"BioNanoTox and Toxicity: using Technology to Advance Discovery" was this year's theme at the 5th BioNanoTox and Applications International Research Conference held at the Peabody Hotel, Little Rock, Arkansas on November 4-5th, 2010. This year, the international participation in this conference increased to 25 countries spanning the globe. The conference began with opening remarks by Paul Howard, Associate Director of the National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, United States. Two keynote speakers, Dr. Ananth V. Annapragada and Dr. Merle G. Paule presented lectures on "Toxicity of Novel Nanoparticles for CT imaging" and "The Biology of Neurotoxicity: using Technology to Advance Discovery", respectively. Teachers, students, faculty, and scientists presented oral and poster presentations on fundamental and translational research related to BioNanoTox and related fields of science. Six presentation sessions were held over the two-day conference. There were 31 presentations and 39 posters from disciplines ranging from biology to chemistry, toxicology, nanotechnology, computational sciences, mathematics, engineering, plant science, and biotechnology. Poster presentation awards were presented to three high school students, three high school teachers, and three college students. In addition to poster awards a memorial, travel, and BioNanoTox award were presented. This year's meeting paved the way for a more outstanding meeting for the future.

FOREWORD: 4th International Workshop on New Computational Methods for Inverse Problems (NCMIP2014)

Science.gov (United States)

2014-10-01

This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 4th International Workshop on New Computational Methods for Inverse Problems, NCMIP 2014 (http://www.farman.ens-cachan.fr/NCMIP_2014.html). This workshop took place at Ecole Normale Supérieure de Cachan, on May 23, 2014. The prior editions of NCMIP also took place in Cachan, France, firstly within the scope of ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/), and secondly at the initiative of Institut Farman, in May 2012 and May 2013, (http://www.farman.ens-cachan.fr/NCMIP_2012.html), (http://www.farman.ens-cachan.fr/NCMIP_2013.html). The New Computational Methods for Inverse Problems (NCMIP) Workshop focused on recent advances in the resolution of inverse problems. Indeed, inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finances. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the

Preface - The 27th International Conference on Phenomena in Ionized Gase

NARCIS (Netherlands)

Kroesen, G.M.W.; Kroesen, G.M.W.

2006-01-01

The 27th International Conference on Phenomena in Ionized Gases (ICPIG) was held in the conference resort of NH Koningshof in Veldhoven, near Eindhoven, The Netherlands, 17–22 July 2005. ICPIG is an important biennial event at which academics and industrialists working in low-temperature plasma

A study on technical issues of materials and design bases in ASME section III subsection NH code

International Nuclear Information System (INIS)

Lee, Hyeong Yeon; Kim, Jong Bum; Yoo, Bong

2000-12-01

In this study, an analysis of evaluation report by ORNL on the technical issues of elevated temperatures design guide line, ASME Code Section III Subsection NH was conducted and a brief evaluation procedure of the creep-fatigue damage was presented. ORNL published the report in 1993 and reviewed the issue areas where code rules or regulatory guides may be lacking or inadequate to ensure safe operation over the expected life cycles for liquid metal reactor systems. From historical viewpoint of the ASME NH code development, ASME Code Case 47 was changed much in 1989 edition, which includes the stress relaxation behavior in creep damage evaluation. Afterwards the 1992 version of CC N-47 was upgraded to Subsection NH in 1995 edition, which is the same with that of CC N-47 1992 edition except few material data. This report brings up the technical and regulatory issues that can not guarantee the safe and reliable operation of the ALMR which got the conceptual design certification from NRC. Twenty three technical issues were raised and settlement methodology were proposed. Additionally, the status of items approved by ASME code subgroup of elevated temperature design committee for the revision of the most recent 1998 edition of ASME NH was described

19th International Conference on Difference Equations and Applications

CERN Document Server

Cushing, Jim; Elaydi, Saber

2014-01-01

This volume contains the proceedings of the 19th International Conference on Difference Equations and Applications, held at Sultan Qaboos University, Muscat, Oman in May 2013. The conference brought together experts and novices in the theory and applications of difference equations and discrete dynamical systems. The volume features papers in difference equations and discrete time dynamical systems with applications to mathematical sciences and, in particular, mathematical biology, ecology, and epidemiology. It includes four invited papers and eight contributed papers. Topics covered include: competitive exclusion through discrete time models, Benford solutions of linear difference equations, chaos and wild chaos in Lorenz-type systems, advances in periodic difference equations, the periodic decomposition problem, dynamic selection systems and replicator equations, and asymptotic equivalence of difference equations in Banach Space. This book will appeal to researchers, scientists, and educators who work in th...

Studies on the Th biodistribution in internal contamination by the fission track method using animals

International Nuclear Information System (INIS)

Ciubotariu, M.; Danis, A.; Dumitrescu, G.; Cucu, M.

1998-01-01

In our previous studies on the U internal contamination, qualitative and quantitative results were obtained by using the fission track methods. In order to obtain complete data on the fissionable element internal contamination using animals, we started a similar study using Th as contaminating element and Wistar London breed rats as laboratory animals. Different ways to obtain internal contaminations were investigated: ingestion, inhalation, absorption by skin and through wounds. In this stage, Wistar-London breed rats of the same sex, weight and age were internal contaminated by 1 ml Th solution ingestion for each rat corresponding to an Annual Limit Intake.The animals were kept in normal life conditions and under permanent medical surveillance up to their sacrifice. Also, their evacuations where sampled every 24 hours. They were sacrificed at different time intervals after their contamination: 2 days (RAT 1), 7 days (RAT 2) and 14 days (RAT 3). After sacrifice, their vital organs were sampled, weighed, calcined, reweighed and finally analysed by track detection using the fission track micromapping technique. This technique was used in the following conditions: - mica-muscovite as track detector pre-etched for fossil tracks 18 h in HF; - the neutron irradiations were performed in the nuclear reactor VVR-S Bucharest at the neutron fluences of 3x10 15 - 2x10 16 fast neutrons/cm 2 . In order to check whether there is any U contribution to the fission track densities obtained in track detectors, U existing in the rat body due to food and water, the neutron irradiations of the ensembles were performed with and without 1 mm Cd shielding; - the visualization of the Th induced fission tracks were obtained by chemical etching in HF, 3 h at room temperature; - the Th track micromappings obtained in track detectors were studied by optical microscopy using a stereomicroscope WILD M7S for ensemble study (X6-X31) and a binocular ZEISS JENA microscope for qualitative and

ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target.

Directory of Open Access Journals (Sweden)

Yongsoon Kim

Full Text Available In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals.

ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target.

Science.gov (United States)

Kim, Yongsoon; Sun, Hong

2012-01-01

In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS) pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM) is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals.

ASM-3 Acid Sphingomyelinase Functions as a Positive Regulator of the DAF-2/AGE-1 Signaling Pathway and Serves as a Novel Anti-Aging Target

Science.gov (United States)

Kim, Yongsoon; Sun, Hong

2012-01-01

In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS) pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM) is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals. PMID:23049887

Abelian Sandpile Model (ASM) and Infinite Volume Limit

Indian Academy of Sciences (India)

ASM- Properties. Any possible sequence of topplings leads to the same stable configuration [Dhar]. The result of particle addition at and subsequent relaxation is given by an operator. £ бвд £ евд £. , where вд £. ¢. ¦. ¤ззз ¤ вг иг . £. ©. ¢ йа£. (Abelian). 7-b ...

Extended networks, porous sheets, and chiral frameworks. Thorium materials containing mixed geometry anions: Structures and properties of Th(SeO3)(SeO4), Th(IO3)2(SeO4)(H2O)3.H2O, and Th(CrO4)(IO3)2

International Nuclear Information System (INIS)

Sullens, Tyler A.; Almond, Philip M.; Byrd, Jessica A.; Beitz, James V.; Bray, Travis H.; Albrecht-Schmitt, Thomas E.

2006-01-01

Three novel Th(IV) compounds containing heavy oxoanions, Th(SeO 3 )(SeO 4 ) (1), Th(IO 3 ) 2 (SeO 4 )(H 2 O) 3 .H 2 O (2), and Th(CrO 4 )(IO 3 ) 2 (3), have been synthesized under mild hydrothermal conditions. Each of these three distinct structures contain trigonal pyramidal and tetrahedral oxoanions. Compound 1 adopts a three-dimensional structure formed from ThO 9 tricapped trigonal prisms, trigonal pyramidal selenite, SeO 3 2- , anions containing Se(IV), and tetrahedral selenate, SeO 4 2- , anions containing Se(VI). The structure of 2 contains two-dimensional porous sheets and occluded water molecules. The Th centers are found as isolated ThO 9 tricapped trigonal prisms and are bound by four trigonal pyramidal iodate anions, two tetrahedral selenate anions, and three coordinating water molecules. In the structure of 3, the Th(IV) cations are found as ThO 9 tricapped trigonal prisms. Each Th center is bound by six IO 3 1- anions and three CrO 4 2- anions forming a chiral three-dimensional structure. Second-harmonic generation of 532nm light from 1064nm radiation by a polycrystalline sample of 3 was observed. Crystallographic data (193K, MoKα, λ=0.71073): 1; monoclinic, P2 1 /c; a=7.0351(5)A, b=9.5259(7)A, c=9.0266(7)A, β=103.128(1), Z=4, R(F)=2.47% for 91 parameters with 1462 reflections with I>2σ(I); 2, monoclinic, P2 1 /n, a=7.4889(9)A, b=8.002(1)A, c=20.165(3)A, β=100.142(2), Z=4, R(F)=4.71% for 158 parameters with 2934 reflections with I>2σ(I); 3, orthorhombic, P2 1 2 1 2 1 , a=7.3672(5)A, b=9.3617(6)A, c=11.9201(7)A, Z=4, R(F)=2.04% for 129 parameters with 2035 reflections with I>2σ(I)

18th International Laser Radar Conference

CERN Document Server

Neuber, Roland; Rairoux, Patrick; Wandinger, Ulla

1997-01-01

Lidar or laser radar, the depth-resolved remote measurement of atmospheric parameters with optical means, has become an important tool in the field of atmospheric and environmental remote sensing. In this volume the latest progress in the development of lidar methods, experiments, and applications is described. The content is based on selected and thoroughly refereed papers presented at the 18th International Laser Radar Conference, Berlin, 22-26 July 1996. The book is divided into six parts which cover the topics of tropospheric aerosols and clouds, lidar in space, wind, water vapor, troposheric trace gases and plumes, and stratospheric and mesospheric profiling. As a supplement to fundamental lidar textbooks this volume may serve as a guide for scientists, engineers, and graduate students through the blossoming field of modern lidar techniques and their contribution to atmospheric and environmental research.

The 26th International Nuclear Physics Conference

Science.gov (United States)

It was a pleasure to welcome all delegates and accompanying persons to Adelaide for the 26th International Conference in Nuclear Physics, INPC2016. As the major meeting in our field, it was a wonderful opportunity to catch up with colleagues from around the world, learn about the very latest developments and share ideas. We were grateful for the support of the Commission on Nuclear Physics, C12, of the International Union of Pure and Applied Physics (IUPAP), which chose Adelaide to host this meeting. We were also honoured that the President of IUPAP, Prof. Bruce McKellar was present at the meeting to welcome delegates and participate in the proceedings. We acknowledge the financial support for the conference which was made available by a number of organisations. We were especially grateful to the major sponsors, the Adelaide Convention Bureau, the University of Adelaide, the Australian National University and ANSTO, as well as IUPAP, the ARC Centre of Excellence for Particle Physics at the Terascale (CoEPP) and several of the world's major nuclear physics laboratories, BNL, GSI, JLab and TRIUMF. As a result of these contributions we were able to offer support to attend the conference to more than 50 international students. Not only did we have a superb scientific program but, consistent with IUPAP guidelines, more than 40% of the invited plenary talks were presented by women. In order to reach out to the local community, Cynthia Keppel (from JLab) presented a public lecture on Hadron Beam Therapy on Tuesday evening, September 13th. As presenting a talk is now often a condition for financial support to attend an international conference, there were 11 simultaneous parallel sessions with more than 350 presentations. We are especially grateful to the International Advisory Committee, the Program Committee and the Conveners whose advice and hard work made it possible for all this to come together. I would also like to acknowledge the work of the Local Organising

The 12th International ICIT Conference Progress in Cryogenics and Isotopes Separation. Proceedings

International Nuclear Information System (INIS)

Stefanescu, Ioan

2006-01-01

The proceedings of the 12th International ICIT Conference Progress in Cryogenics and Isotopes Separation held in Caciulata, Romania on 25-27 October 2006 contain plenary lectures (11 papers) and 7 sections addressing the following subject matters: Section 1. Stable Isotopes Physics. Technologies and Applications (6 papers); Section 2. Cryogenics Technologies and Equipment (6 papers); Section 3. Science and Materials Engineering (18 papers); Section 4. Nuclear Power (17 papers); Section 5. Hydrogen and Fuel Cells (14 papers); Section 6. Environmental Protection. Industrial Risk (14 papers); Section 7. Laboratory Analysis Methods (13 papers). A number of 40 papers are available in abstract form only and accordingly full text entered the corresponding records

5th International Conference on Mathematical Modeling in Physical Sciences (IC-MSquare 2016)

International Nuclear Information System (INIS)

Vagenas, Elias C.; Vlachos, Dimitrios S.

2016-01-01

The 5th International Conference on Mathematical Modeling in Physical Sciences (IC- MSQUARE) took place at Athens, Greece, from Monday, 23"t"h of May, to Thursday, 26"t"h of May 2016. The Conference was attended by more than 130 participants and hosted about 170 oral, poster, and virtual presentations while counted more than 500 pre-registered authors. The 5"t"h IC-MSQUARE consisted of different and diverging workshops and thus covered various research fields where Mathematical Modeling is used, such as Theoretical/Mathematical Physics, Neutrino Physics, Non-Integrable Systems, Dynamical Systems, Computational Nanoscience, Biological Physics, Computational Biomechanics, Complex Networks, Stochastic Modeling, Fractional Statistics, DNA Dynamics, Macroeconomics etc. The scientific program was rather heavy since after the Keynote and Invited Talks in the morning, three parallel oral and one poster session were running every day. However, according to all attendees, the program was excellent with high level talks and the scientific environment was fruitful, thus all attendees had a creative time. We would like to thank the Keynote Speaker and the Invited Speakers for their significant contribution to IC-MSQUARE. We also would like to thank the Members of the International Advisory and Scientific Committees as well as the Members of the Organizing Committee. (paper)

Dysregulated cytokine expression by CD4+ T cells from post-septic mice modulates both Th1 and Th2-mediated granulomatous lung inflammation.

Directory of Open Access Journals (Sweden)

William F Carson

Full Text Available Previous epidemiological studies in humans and experimental studies in animals indicate that survivors of severe sepsis exhibit deficiencies in the activation and effector function of immune cells. In particular, CD4+ T lymphocytes can exhibit reduced proliferative capacity and improper cytokine responses following sepsis. To further investigate the cell-intrinsic defects of CD4+ T cells following sepsis, splenic CD4+ T cells from sham surgery and post-septic mice were transferred into lymphopenic mice. These recipient mice were then subjected to both TH1-(purified protein derivative and TH2-(Schistosoma mansoni egg antigen driven models of granulomatous lung inflammation. Post-septic CD4+ T cells mediated smaller TH1 and larger TH2 lung granulomas as compared to mice receiving CD4+ T cells from sham surgery donors. However, cytokine production by lymph node cells in antigen restimulation assays indicated increased pan-specific cytokine expression by post-septic CD4+ T cell recipient mice in both TH1 and TH2 granuloma models. These include increased production of T(H2 cytokines in TH1 inflammation, and increased production of T(H1 cytokines in TH2 inflammation. These results suggest that cell-intrinsic defects in CD4+ T cell effector function can have deleterious effects on inflammatory processes post-sepsis, due to a defect in the proper regulation of TH-specific cytokine expression.

20th International Congress of Theoretical and Applied Mechanics, ICTAM2000

Energy Technology Data Exchange (ETDEWEB)

Hassan, Aref

2000-08-27

The 20th International Congress of Theoretical and Applied Mechanics, ICTAM2000, was held in Chicago, IL, from August 27 - September 2, 2000. It was 32 years since the last of these congresses had been held in USA. A record number of researchers in the mechanical engineering sciences attended and presented their work. The Congress provided an opportunity for the US mechanics community to act as international hosts. Several universities, professional societies, private foundations and individuals, and Federal agencies provided financial support for the Congress.

17th International Congress of Biometeorology (ICB) 2005. Vol. 1. Proceedings

International Nuclear Information System (INIS)

Anon.

2005-01-01

The theme of the 17th International Congress of Biometeorology is adaptation to weather, climate, and climate change. Volume 1 of the congress proceedings contains 141 contributions. They are sorted under the following lecture topics: agriculture and forest, air pollution, animals, artificial/indoor/urban, climate change, history of biometeorology, human. (uke)

5th International Conference on Sustainable Automotive Technologies

CERN Document Server

Subic, Aleksandar; Trufin, Ramona

2014-01-01

This book captures selected peer reviewed papers presented at the 5th International Conference on Sustainable Automotive Technologies, ICSAT 2013, held in Ingolstadt, Germany. ICSAT is the state-of-the-art conference in the field of new technologies for transportation. The book brings together the work of international researchers and practitioners under the following interrelated headings: fuel transportation and storage, material recycling, manufacturing and management costs, engines and emission reduction. The book provides a very good overview of research and development activities focused on new technologies and approaches capable of meeting the challenges to sustainable mobility. About the Editors: Prof. Dr. Jörg Wellnitz is the Dean of the Faculty of Mechanical Engineering, Technische Hochschule Ingolstadt, Germany. Prof. Dr. Aleksandar Subic is the Head of the School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Australia. Ramona Trufin, M.A. is the coordinator of the Facul...

Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect.

Science.gov (United States)

Patel, Brijeshkumar S; Kugel, Michael J; Baehring, Gina; Ammit, Alaina J

2017-08-01

The xanthine doxofylline has been examined in clinical trials and shown to have efficacy and greater tolerability than theophylline in asthma and chronic obstructive pulmonary disease. The 'novofylline' doxofylline has demonstrated bronchodilatory and anti-inflammatory actions in in vivo and ex vivo experimental models of respiratory disease. However, there are limited studies in vitro. We address this herein and examine whether doxofylline has anti-inflammatory impact on primary cultures of airway smooth muscle (ASM) cells. We conduct a series of investigations comparing and contrasting doxofylline with the archetypal xanthine, theophylline, and the specific phosphodiesterase (PDE) 4 inhibitor, cilomilast. We confirm that the xanthine drugs do not have action as PDE inhibitors in ASM cells. Unlike cilomilast, doxofylline (and theophylline) do not increase cAMP production in ASM cells induced by long-acting β 2 -agonist formoterol. Similar to theophylline, and consistent with the lack of cAMP potentiation, doxofylline does not augment formoterol-induced upregulation of the anti-inflammatory protein mitogen-activated protein kinase phosphatase 1 (MKP-1). However, when we examine the effect of doxofylline on secretion of the interleukin 8 from ASM cells stimulated by tumour necrosis factor (an in vitro surrogate measure of inflammation), there was no repression of inflammation. This is in contrast to the anti-inflammatory impact exerted by theophylline and cilomilast in confirmatory experiments. In summary, our study is the first to examine the effect of doxofylline on ASM cells in vitro and highlights some distinct differences between two key members of xanthine drug family, doxofylline and theophylline. Copyright © 2017 Elsevier Ltd. All rights reserved.

46 CFR 53.01-3 - Adoption of section IV of the ASME Boiler and Pressure Vessel Code.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section IV of the ASME Boiler and Pressure...) MARINE ENGINEERING HEATING BOILERS General Requirements § 53.01-3 Adoption of section IV of the ASME Boiler and Pressure Vessel Code. (a) Heating boilers shall be designed, constructed, inspected, tested...

10th International Symposium on Computer Science in Sports

CERN Document Server

Soltoggio, Andrea; Dawson, Christian; Meng, Qinggang; Pain, Matthew

2016-01-01

This book presents the main scientific results of the 10th International Symposium of Computer Science in Sport (IACSS/ISCSS 2015), sponsored by the International Association of Computer Science in Sport in collaboration with the International Society of Sport Psychology (ISSP), which took place between September 9-11, 2015 at Loughborough, UK. This proceedings aims to build a link between computer science and sport, and reports on results from applying computer science techniques to address a wide number of problems in sport and exercise sciences. It provides a good platform and opportunity for researchers in both computer science and sport to understand and discuss ideas and promote cross-disciplinary research. The strictly reviewed and carefully revised papers cover the following topics: Modelling and Analysis, Artificial Intelligence in Sport, Virtual Reality in Sport,  Neural Cognitive Training,  IT Systems for Sport, Sensing Technologies and Image Processing.

Proceedings of 15th International Conference on Heavy Metals in the Environment

International Nuclear Information System (INIS)

Barganska, Z.; Beyer, A; Klimaszewska, K.; Namiesnik, J.; Tobiszewski, M.; Rutkiewicz, I.

2010-01-01

15 th International Conference on Heavy Metals in the Environment (15 th ICHMET) is a continuation of a series of conferences that have been held since 1975. These conferences typically draw 500-1000 participants from countries in many parts of the world. The ICHMETs are the only forum that provide an integrated perspective on research and policy initiatives on all heavy metals in a trans-disciplinary context. There is a need to understand not only the unique features and behavior of individual heavy metals but also the differences, similarities and interactions of different metals at the ecosystem, systemic and cellular levels if we are to deal with the problems of global heavy metal pollution in a sustainable manner. The presented contributions concerned problems: (1) trend tracking/analysis of heavy metals data; (2) analytical tools and techniques; (3) heavy metals in the marine environment; (4) accumulation in foods and crops; (5) soil contamination; (6) heavy metals in sediments and remediation technologies; (7) effects on human health; (8) heavy metals in the atmosphere; (9) sources, emissions and control of heavy metals; (10) phytoremediation; (11) wastewater treatment; (12) heavy metals in the historical pollution record.

Upregulation of Tim-3 on CD4(+) T cells is associated with Th1/Th2 imbalance in patients with allergic asthma.

Science.gov (United States)

Tang, Fei; Wang, Fukun; An, Liyun; Wang, Xianling

2015-01-01

T cell Ig and mucin domain-containing molecule-3 (Tim-3) is a negative regulator preferentially expressed on Th1 cells. Allergic asthma is a clinical syndrome well characterized by Th1/Th2 imbalance. To investigate the role of Tim-3 in the pathogenesis of asthma and its relationship with Th1/Th2 imbalance, a total of 40 patients with allergic asthma and 40 healthy controls were enrolled. Expression of Tim-3 and Th1/Th2 imbalance as well as the relationship between them was analyzed by flow cytometry and real-time PCR. Peripheral blood mononuclear cells (PBMCs) were cultured in vitro and anti-Tim-3 was used to block Tim-3 signaling; Th1/Th2 cytokines in the culture supernatant were detected by enzyme linked immunosorbent assay (ELISA). CD4(+) T cells and B cells were sorted and co-cultured in vitro, and anti-Tim-3 was used to block Tim-3 signaling; Total IgG/IgE in the culture supernatant was detected by ELISA. The mRNA level of T-bet and IFN-γ were significantly decreased in allergic asthma patients, while GATA-3 and IL-4 were significantly increased. Expression of Tim-3 on CD4(+) T cells was much higher in allergic asthma patients and it was negatively correlated with T-bet/GATA-3 ratio or IFN-γ/IL-4 ratio. Blocking of Tim-3 significantly increased Th1 cytokines (TNF-α and IFN-γ) and decreased Th2 cytokines (IL-4, IL-5, IL-13) in the culture supernatant of PBMCs. Blocking of Tim-3 dramatically reduced the production of IgG and IgE in the co-culture supernatant of CD4(+) T cells and B cells. In conclusion, Tim-3 was up-regulated in allergic asthma patients and related with the Th1/Th2 imbalance. Blocking of Tim-3 may be of therapeutic benefit by enhancing the Th1 cytokines response, down-regulating the Th2 cytokines response, and reducing IgG/IgE production.

46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section I of the ASME Boiler and Pressure...) MARINE ENGINEERING POWER BOILERS General Requirements § 52.01-2 Adoption of section I of the ASME Boiler and Pressure Vessel Code. (a) Main power boilers and auxiliary boilers shall be designed, constructed...

FOREWORD: 9th International Conference on Compressors and their Systems

Science.gov (United States)

Kovacevic, Ahmed, Prof

2015-08-01

The 9th International Conference on Compressors and their Systems will be held in London from 5th - 9th September 2015, and as its Chairman, it is my pleasure to welcome you. This series of conferences started in 1999 organised by the Fluid Machinery Group of the Institution of Mechanical Engineers (IMechE) but since 2009 it has been managed by City University London in conjunction with the IMechE and the Institute of Refrigeration, both of which have been very proactive in promoting it. The Organising committee is grateful for their support and continued encouragement. This year, after rigorous reviewing, we have accepted over 80 technical papers for publication, the highest number in the conference history. On behalf of the organising committee I would like to thank the reviewers for their hard work and assistance. In addition to the main technical sessions, this year we have introduced a third day, specifically for Industry, to consider technology, business and market drivers on compressor developments. The traditional series of the short courses is this year continuing prior to the main event with the second short course/forum on Computational Fluid Dynamics in rotating positive displacement machines. I would like to extend my special thanks to our main sponsors, Holroyd PTG, Howden and Kapp Niels for their continuing support for the conference. With their generous contributions we have managed to keep the conference fees at the same level as in 2013, despite extending it to 3 days and holding it outside the University this year. The welcome reception on Sunday 6th September 2015 is dedicated to the celebration of the 20th anniversary of the Centre for Positive Displacement Compressors Technology which was formed at City University in 1995 with support from the Royal Academy of Engineering and Holroyd; its main aim being to assist British manufacturers of screw compressors. The Centre has since made a significant impact on the screw compressor world, far beyond

Invitation to the 17th international congress on photosynthesis research in 2016

NARCIS (Netherlands)

Amerongen, van Herbert; Croce, Roberta

2016-01-01

The 17th International Congress on Photosynthesis will be held from August 7 to 12, 2016 in Maastricht, The Netherlands. The congress will include an opening reception, 15 plenary lectures, 28 scientific symposia, many poster sessions, displays by scientific companies, excursions, congress

12th International Workshop on Low Temperature Electronics

International Nuclear Information System (INIS)

2017-01-01

The present volume of the Journal of Physics: Conference Series represents contributions from participants of the 12th International Workshop on Low Temperature Electronics held in Tempe, Arizona, USA from September 18-21, 2016. The conference was organized by the School of Earth and Space Exploration at Arizona State University.The International Workshop on Low Temperature Electronics (WOLTE) is a biennial conference devoted to the presentation and exchange of the most recent advances in the field of low temperature electronics and its applications. This international forum is open to everyone in the field.The technical program included oral presentations and posters on fundamental properties of cryogenic materials, cryogenic transistors, quantum devices and systems, astronomy and physics instrumentation, and fabrication of cryogenic devices. More than 50 scientists and engineers from various academic, government, and industrial institutions in Europe, Asia, and the Americas attended the conference.We would like to thank all speakers for their presentations and all attendees for their participation. We would also like to express our sincerest gratitude to our sponsors: Lake Shore Cryotronics, ASU NewSpace, ASU School of Earth and Space Exploration, and IRA A. Fulton Schools of Engineering for making this conference possible. (paper)

Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells.

Science.gov (United States)

Leal Rojas, Ingrid M; Mok, Wai-Hong; Pearson, Frances E; Minoda, Yoshihito; Kenna, Tony J; Barnard, Ross T; Radford, Kristen J

2017-01-01

Dendritic cells (DC) initiate the differentiation of CD4 + helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis. In mice, Th1 and Th17 responses are regulated by different conventional (c) DC subsets, with cDC1 being the main producers of IL-12p70 and inducers of Th1 responses, while cDC2 produce IL-23 to promote Th17 responses. The role that human DC subsets play in memory CD4 + T cell activation is not known. This study investigated production of Th1 promoting cytokine IL-12p70, and Th17 promoting cytokines, IL-1β, IL-6, and IL-23, by human blood monocytes, CD1c + DC, CD141 + DC, and plasmacytoid DC and examined their ability to induce Th1 and Th17 responses in memory CD4 + T cells. Human CD1c + DC produced IL-12p70, IL-1β, IL-6, and IL-23 in response to R848 combined with LPS or poly I:C. CD141 + DC were also capable of producing IL-12p70 and IL-23 but were not as proficient as CD1c + DC. Activated CD1c + DC were endowed with the capacity to promote both Th1 and Th17 effector function in memory CD4 + T cells, characterized by high production of interferon-γ, IL-17A, IL-17F, IL-21, and IL-22. These findings support a role for CD1c + DC in autoimmune inflammation where Th1/Th17 responses play an important role in disease pathogenesis.

Estimates of the burst reliability of thin-walled cylinders designed to meet the ASME Code allowables

International Nuclear Information System (INIS)

Stancampiano, P.A.; Zemanick, P.P.

1976-01-01

Pressure containment components in nuclear power plants are designed by the conventional deterministic safety factor approach to meet the requirements of the ASME Pressure Vessel Code, Section III. The inevitable variabilities and uncertainties associated with the design, manufacture, installation, and service processes suggest a probabilistic design approach may also be pertinent. Accordingly, the burst reliabilities of two thin-walled 304 SS cylindrical vessels such as might be employed in liquid metal plants are estimated. A large vessel fabricated from rolled plate per ASME SA-240 and a smaller pipe sized vessel also fabricated from rolled plate per ASME SA-358 are considered. The vessels are sized to just meet the allowable ASME Code primary membrance stresses at 800 0 F (427 0 C). The bursting probability that the operating pressure is greater than the burst strength of the cylinders is calculated using stress-strength interference theory by direct Monte Carlo simulation on a high speed digital computer. A sensitivity study is employed to identify those design parameters which have the greatest effect on the reliability. The effects of preservice quality assurance defect inspections on the reliability are also evaluated parametrically

A Survey of Variable Extragalactic Sources with XTE's All Sky Monitor (ASM)

Science.gov (United States)

Jernigan, Garrett

1998-01-01

The original goal of the project was the near real-time detection of AGN utilizing the SSC 3 of the ASM on XTE which does a deep integration on one 100 square degree region of the sky. While the SSC never performed sufficiently well to allow the success of this goal, the work on the project has led to the development of a new analysis method for coded aperture systems which has now been applied to ASM data for mapping regions near clusters of galaxies such as the Perseus Cluster and the Coma Cluster. Publications are in preparation that describe both the new method and the results from mapping clusters of galaxies.

Introduction to the special issue on the joint meeting of the 19th IEEE International Symposium on the Applications of Ferroelectrics and the 10th European Conference on the Applications of Polar Dielectrics.

Science.gov (United States)

Tsurumi, Takaaki

2011-09-01

The joint meeting of the 19th IEEE International Symposium on the Applications of Ferroelectrics and the 10th European Conference on the Applications of Polar Dielectrics took place in Edinburgh from August 9-12, 2010. The conference was attended by 390 delegates from more than 40 different countries. There were 4 plenary speakers, 56 invited speakers, and a further 222 contributed oral presentations in 7 parallel session. In addition there were 215 poster presentations. Key topics addressed at the conference included piezoelectric materials, leadfree piezoelectrics, and multiferroics.

PREFACE: 12th Russia/CIS/Baltic/Japan Symposium on Ferroelectricity and 9th International Conference on Functional Materials and Nanotechnologies (RCBJSF-2014-FM&NT)

Science.gov (United States)

Sternberg, Andris; Grinberga, Liga; Sarakovskis, Anatolijs; Rutkis, Martins

2015-03-01

The joint International Symposium RCBJSF-2014-FM&NT successfully has united two international events - 12th Russia/CIS/Baltic/Japan Symposium on Ferroelectricity (RCBJSF-12) and 9th International Conference Functional Materials and Nanotechnologies (FM&NT-2014). The RCBJSF symposium is a continuation of series of meetings on ferroelectricity, the first of which took place in Novosibirsk (USSR) in 1976. FM&NT conferences started in 2006 and have been organized by Institute of Solid State Physics, University of Latvia in Riga. In 2012 the International program committee decided to transform this conference into a traveling Baltic State conference and the FM&NT-2013 was organized by the Institute of Physics, University of Tartu, Estonia. In 2014 the joint international symposium RCBJSF-2014-FM&NT was organized by the Institute of Solid State Physics, University of Latvia and was part of Riga - 2014, the European Capital of Culture event. The purpose of the joint Symposium was to bring together scientists, students and high-level experts in solid state physics, materials science, engineering and related disciplines. The number of the registered participants from 26 countries was over 350. During the Symposium 128 high quality scientific talks (5 plenary, 42 invited, 81 oral) and over 215 posters were presented. All presentations were divided into 4 parallel sessions according to 4 main topics of the Symposium: Ferroelectricity, including ferroelectrics and multiferroics, pyroelectrics, piezoelectrics and actuators, integrated ferroelectrics, relaxors, phase transitions and critical phenomena. Multifunctional Materials, including theory, multiscale and multiphenomenal material modeling and simulation, advanced inorganic, organic and hybrid materials. Nanotechnologies, including progressive methods, technologies and design for production, investigation of nano- particles, composites, structures, thin films and coatings. Energy, including perspective materials and

6th International Conference on the Physics Opportunities at an ElecTron-Ion Collider

CERN Document Server

Sabatié, F; POETIC6

2015-01-01

POETIC6, the 6th edition of the International Conference on the "Physics Opportunities at an ElecTron-Ion Collider", will take place at Ecole Polytechnique in Palaiseau, France from Monday, September 7th to Friday, September 11th 2015, a few weeks before the National Science Advisory Committee recommends a new Long Range Plan to the United States' DOE and NSF. In the midst of this much-anticipated report, and following earlier workshops at Stellenbosch, Bloomington, Valparaiso, Jyvaskyla and Yale, it is timely for the POETIC series to become an international conference. The primary goal will remain to continue the advancement of the field of electron-ion collider physics. While the central theme of the conference will be the physics of a future electron-ion collider, the workshop will also cover strongly-related physics in the CEBAF, RHIC, and LHC experimental programs. The conference will aim primarily at developments on the theory/phenomenology side, but the latest accelerator and experimental developments ...

The Expression of NOX4 in Smooth Muscles of Small Airway Correlates with the Disease Severity of COPD.

Science.gov (United States)

Liu, Xianyan; Hao, Binwei; Ma, Ailing; He, Jinxi; Liu, Xiaoming; Chen, Juan

Airway smooth muscle (ASM) remodeling is a hallmark in chronic obstructive pulmonary disease (COPD), and nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases (NOXs) produced reactive oxygen species (ROS) play a crucial role in COPD pathogenesis. In the present study, the expression of NOX4 and its correlation with the ASM hypertrophy/hyperplasia, clinical pulmonary functions, and the expression of transforming growth factor β (TGF- β ) in the ASM of COPD small airways were investigated by semiquantitative morphological and/or immunohistochemistry staining methods. The results showed that an elevated expression of NOX4 and TGF- β , along with an increased volume of ASM mass, was found in the ASM of small airways in COPD patients. The abundance of NOX4 protein in the ASM was increased with disease severity and inversely correlated with the pulmonary functions in COPD patients. In addition, the expression of NOX4 and ASM marker α -SMA was colocalized, and the increased NOX4 expression was found to accompany an upregulated expression of TGF- β in the ASM of small airways of COPD lung. These results indicate that NOX4 may be a key regulator in ASM remodeling of small airway, in part through a mechanism interacting with TGF- β signaling in the pathogenesis of COPD, which warrants further investigation.

7th International Workshop on Parallel Tools for High Performance Computing

CERN Document Server

Gracia, José; Nagel, Wolfgang; Resch, Michael

2014-01-01

Current advances in High Performance Computing (HPC) increasingly impact efficient software development workflows. Programmers for HPC applications need to consider trends such as increased core counts, multiple levels of parallelism, reduced memory per core, and I/O system challenges in order to derive well performing and highly scalable codes. At the same time, the increasing complexity adds further sources of program defects. While novel programming paradigms and advanced system libraries provide solutions for some of these challenges, appropriate supporting tools are indispensable. Such tools aid application developers in debugging, performance analysis, or code optimization and therefore make a major contribution to the development of robust and efficient parallel software. This book introduces a selection of the tools presented and discussed at the 7th International Parallel Tools Workshop, held in Dresden, Germany, September 3-4, 2013.  

10th International Workshop on Parallel Tools for High Performance Computing

CERN Document Server

Gracia, José; Hilbrich, Tobias; Knüpfer, Andreas; Resch, Michael; Nagel, Wolfgang

2017-01-01

This book presents the proceedings of the 10th International Parallel Tools Workshop, held October 4-5, 2016 in Stuttgart, Germany – a forum to discuss the latest advances in parallel tools. High-performance computing plays an increasingly important role for numerical simulation and modelling in academic and industrial research. At the same time, using large-scale parallel systems efficiently is becoming more difficult. A number of tools addressing parallel program development and analysis have emerged from the high-performance computing community over the last decade, and what may have started as collection of small helper script has now matured to production-grade frameworks. Powerful user interfaces and an extensive body of documentation allow easy usage by non-specialists.

10th International Conference on X-Ray Lasers

CERN Document Server

Nickles, P.V; X-Ray Lasers 2006

2007-01-01

The search for table-top and repetitive pump schemes during the last decade has been the driving force behind the spectacular advances demonstrated during the 10th International Conference on X-Ray Lasers, organized in 2006 in Berlin. Since 1986, international experts have gathered every two years at this established conference to discuss the progress in theory, experiment and application of plasma-based soft X-ray lasers. Traditionally, the conference sessions devoted to complementary and alternative sources of short wavelength radiation, such as high harmonics, XFEL or incoherent X-rays are organized so as to emphasize the role of X-ray laser research in relation to the other short wavelength sources. Grazing incidence pumping (GRIP) and seeding with high harmonics were the dominant topics of the conference. High repetition rate and portable X-ray lasers were reported to have been applied in metrology and photochemistry for the first time. The proceedings of this series of conferences constitute a comprehen...

8th International Workshop on Non-Monotonic Reasoning

CERN Document Server

Truszczynski, Mirek

2000-01-01

The papers gathered in this collection were presented at the 8th International Workshop on Nonmonotonic Reasoning, NMR2000. The series was started by John McCarthy in 1978. The first international NMR workshop was held at Mohonk Mountain House, New Paltz, New York in June, 1984, and was organized by Ray Reiter and Bonnie Webber. In the last 10 years the area of nonmonotonic reasoning has seen a number of important developments. Significant theoretical advances were made in the understanding of general abstract principles underlying nonmonotonicity. Key results on the expressibility and computational complexity of nonmonotonic logics were established. The role of nonmonotonic reasoning in belief revision, abduction, reasoning about action, planing and uncertainty was further clarified. Several successful NMR systems were built and used in applications such as planning, scheduling, logic programming and constraint satisfaction. The papers in the proceedings reflect these recent advances in the field. They are g...

Proceedings of the 15th International Congress on Circumpolar Health

OpenAIRE

incl Table of Contents, Complete Supplement,

2013-01-01

Proceedings of the 15th International Congress on Circumpolar Health August 5–10, 2012, Fairbanks, Alaska, USA. This extensive publication includes nearly 100 full length papers, 90 extended abstracts and nearly 100 short abstracts. The full publication is freely available through the journal website.(Published: 5 August 2013)Citation: Int J Circumpolar Health 2013, 72: 22447 - http://dx.doi.org/10.3402/ijch.v72i0.22447

4th ASEM Seminar on Knowledge Management to Enhance Nuclear Safety

International Nuclear Information System (INIS)

Castello, F.; Reyes, A. de los; Sobari, M. P. Mohd; Istiyanto, J. E.; Faross, P.; Delarosa, A.

2016-01-01

Full text: The 4th Asia-Europe Meeting (ASEM) Seminar on Nuclear Safety was convened in Madrid, Spain on 29th–30th October 2015, hosted by the Spanish Nuclear Safety Council. The seminar’s theme was “Knowledge management to enhance nuclear safety”, which aimed to continue discussing on nuclear safety to foster Asia-Europe capacity-building and cooperation in nuclear safety. The seminar was attended by representatives from national governments, nuclear regulators, energy companies, radiation protection and nuclear safety authorities, research institutes and universities. According to such model, proposed by the IAEA, the national capacity building requires an integrated approach based on four pillars: human resources development, education and training, knowledge management and knowledge networking. In this context, Nuclear Knowledge Management (KM) has become a high priority in many countries and international organizations and it has been taken into account to develop and implement specific strategies in ensuring safe and sustainable operation of nuclear facilities. At national level, a sustainable approach should include the necessary Nuclear Knowledge Management actions to ensure that every actor having a significant role in the national nuclear programmes infrastructure acquires, preserves and improves its corporate and individual knowledge. (author

The 4th technological meeting of Tokai Reprocessing Plant

International Nuclear Information System (INIS)

Ohnishi, Tohru; Maki, Akira; Shibata, Satomi; Yatogi, Hideo; Nyui, Daisuke; Hashimoto, Takakazu; Fukuda, Kazuhito; Ohzeki, Tatsuya

2001-11-01

''The 4th technological meeting of Tokai Reprocessing Plant (TRP)'' was held in JNFL Rokkasho site on October 11 th , 2001. The report contains the proceedings, transparencies and questionnaires of the meeting. This time, we reported about ''Maintenance and repair results of Tokai Reprocessing Plant'' based on technology and knowledge accumulated in Tokai Reprocessing Plant. (author)

Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017).

Science.gov (United States)

Barrington, William T; Salvador, Anna C; Hartiala, Jaana A; De Caterina, Raffaele; Kohlmeier, Martin; Martinez, J Alfredo; Kreutzer, Carin B; Heber, David; Lusis, Aldons J; Li, Zhaoping; Allayee, Hooman

2017-01-01

The International Society of Nutrigenetics and Nutrigenomics (ISNN) held its 11th annual Congress in Los Angeles, California, between September 16 and 19, 2017. In addition to 2 keynote lectures, 4 plenary sessions included presentations by internationally renowned speakers on cutting-edge areas of research and new discoveries in genetics/genomics, the microbiome, and nutrition. Scientific topics included multi-omics approaches; diet and the microbiome; cancer, longevity, and metabolism; moving the field forward; and translational/educational aspects and the future of medicine. There was also an accepted oral abstracts session designed specifically to provide young investigators and trainees with the opportunity to present their work, as well as a session focused on industry-academic partnerships, which included a roundtable discussion afterwards. Overall, the 11th ISNN Congress was an exciting and intellectually stimulating meeting focused on understanding the impact of biological interactions between genes and nutrients on health and disease. These efforts continued the decade-long tradition of the annual ISNN Congress to provide an interdisciplinary platform for scientists from various disciplines to discuss research ideas and advance the fields of nutrigenetics and nutrigenomics. © 2018 S. Karger AG, Basel.

Proceedings: 19th International Nondestructive Testing and Evaluation of Wood Symposium

Science.gov (United States)

Robert J. Ross; Raquel Gonçalves; Xiping Wang

2015-01-01

The 19th International Nondestructive Testing and Evaluation of Wood Symposium was hosted by the University of Campinas, College of Agricultural Engineering (FEAGRI/UNICAMP), and the Brazilian Association of Nondestructive Testing and Evaluation (ABENDI) in Rio de Janeiro, Brazil, on September 22–25, 2015. This Symposium was a forum for those involved in nondestructive...

5th International Conference on Electronics, Communications and Networks

CERN Document Server

2016-01-01

This book comprises peer-reviewed contributions presented at the 5th International Conference on Electronics, Communications and Networks (CECNet 2015), held in Shanghai, China, 12-15 December, 2015. It includes new multi-disciplinary topics spanning a unique depth and breadth of cutting-edge research areas in Electronic Engineering, Communications and Networks, and Computer Technology. More generally, it is of interest to academics, students and professionals involved in Consumer Electronics Technology, Communication Engineering and Technology, Wireless Communication Systems and Technology, and Computer Engineering and Technology.

Effects of Public Preschool Expenditures on the Test Scores of 4th Graders: Evidence from TIMSS

Science.gov (United States)

Waldfogel, Jane; Zhai, Fuhua

2011-01-01

This study examines the effects of public preschool expenditures on the math and science scores of 4th graders, holding constant child, family, and school characteristics, other relevant social expenditures, and country and year effects, in seven Organization for Economic Co-operation and Development (OECD) countries -- Australia, Japan, Netherlands, New Zealand, Norway, U.K., and U.S -- using data from the 1995 and 2003 Trends in International Mathematics and Science Study (TIMSS). Our results indicate that there are small but significant positive effects of public preschool expenditures on the math and science scores of 4th graders and preschool expenditures reduce the risk of children scoring at the low level of proficiency. We also find some evidence that children from low-resource homes and homes where the test language is not always spoken may tend to gain more from increased public preschool expenditures than other children,. PMID:21442008

PREFACE: The 15th International Couette-Taylor Worskhop

Science.gov (United States)

Mutabazi, Innocent; Crumeyrolle, Olivier

2008-07-01

The 15th International Couette-Taylor Worskhop (ICTW15) was held in Le Havre, France from 9-12 July 2007. This regular international conference started in 1979 in Leeds, UK when the research interest in simple models of fluid flows was revitalized by systematic investigation of Rayleigh-Bénard convection and the Couette-Taylor flow. These two flow systems are good prototypes for the study of the transition to chaos and turbulence in closed flows. The workshop themes have been expanded from the original Couette-Taylor flow to include other centrifugal instabilities (Dean, Görtler, Taylor-Dean), spherical Couette flows, thermal convection instabilities, MHD, nonlinear dynamics and chaos, transition to turbulence, development of numerical and experimental techniques. The impressive longevity of the ICTW is due to the close interaction and fertile exchanges between international research groups from different disciplines: Physics and Astrophysics, Applied Mathematics, Mechanical Engineering, Chemical Engineering. The present workshop was attended by 100 participants, the program included over 83 contributions with 4 plenary lectures, 68 oral communications and 17 posters. The topics include, besides the classical Couette-Taylor flows, the centrifugal flows with longitudinal vortices, the shear flows, the thermal convection in curved geometries, the spherical Couette-Taylor flow, the geophysical flows, the magneto-hydrodynamic effects including the dynamo effect, the complex flows (viscoelasticity, immiscible fluids, bubbles and migration). Selected papers have been processed through the peer review system and are published in this issue of the Journal of Physics: Conference Series. The Workshop has been sponsored by Le Havre University, the Region Council of Haute-Normandie, Le Havre City Council, CNRS (ST2I, GdR-DYCOEC), and the European Space Agency through GEOFLOW program. The French Ministry of Defense (DGA), the Ministry of Foreign Affairs, the Ministry of

7th International Conference in Methodologies and Intelligent Systems for Technology Enhanced Learning

CERN Document Server

Gennari, Rosella; Mascio, Tania; Rodríguez, Sara; Prieta, Fernando; Ramos, Carlos; Silveira, Ricardo

2017-01-01

This book presents the outcomes of the 7th International Conference in Methodologies and Intelligent Systems for Technology Enhanced Learning (MIS4TEL'17), hosted by the Polytechnic of Porto, Portugal from 21 to 23 June 2017. Expanding on the topics of the previous conferences, it provided an open forum for discussing intelligent systems for technology enhanced learning (TEL) and their roots in novel learning theories, empirical methodologies for their design or evaluation, stand-alone and web-based solutions, and makerspaces. It also fostered entrepreneurship and business startup ideas, bringing together researchers and developers from industry, education and the academic world to report on the latest scientific research, technical advances and methodologies.

6th International Conference on Practical Applications of Computational Biology & Bioinformatics

CERN Document Server

Luscombe, Nicholas; Fdez-Riverola, Florentino; Rodríguez, Juan; Practical Applications of Computational Biology & Bioinformatics

2012-01-01

The growth in the Bioinformatics and Computational Biology fields over the last few years has been remarkable.. The analysis of the datasets of Next Generation Sequencing needs new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Also Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. This book presents the results of the  6th International Conference on Practical Applications of Computational Biology & Bioinformatics held at University of Salamanca, Spain, 28-30th March, 2012 which brought together interdisciplinary scientists that have a strong background in the biological and computational sciences.

Recommendations to ASME for code guidelines and criteria for continued operation of equipment

International Nuclear Information System (INIS)

Harvey, J.F.

1993-01-01

In May 1988, the American Society of Mechanical Engineers, ASME, asked the Pressure Vessel Research Council, PVRC, to review the part it should play in the continued operation of equipment originally designed and fabricated to the ASME codes and rules. This was prompted solely by an economic opportunity in which the capital expenditures to replace plants was far more costly than evaluating, repairing, and extending the nominal design life of the individual component. For instance, nuclear plants are normally designed for a life of 40 years, while fossil fired facilities may have been designed for other time lives, yet at the end of their original design life may actually have many useful years remaining. While this action was economically prompted, it inherently involved a two-fold one; namely, (1) safety, (2) legal. There is no question of safety to operating personnel. While codes for fossil components do not specify design lives, their adoption by many states provides a legal means of procedure in event of a mishap. This recognizes a cradle-to-grave safety responsibility. It is toward maintaining ASMEs leadership as a code authority that this report has been prepared

TH-E-17A-01: Internal Respiratory Surrogate for 4D CT Using Fourier Transform and Anatomical Features

Energy Technology Data Exchange (ETDEWEB)

Hui, C; Suh, Y; Robertson, D; Pan, T; Das, P; Crane, C; Beddar, S [MD Anderson Cancer Center, Houston, TX (United States)

2014-06-15

Purpose: To develop a novel algorithm to generate internal respiratory signals for sorting of four-dimensional (4D) computed tomography (CT) images. Methods: The proposed algorithm extracted multiple time resolved features as potential respiratory signals. These features were taken from the 4D CT images and its Fourier transformed space. Several low-frequency locations in the Fourier space and selected anatomical features from the images were used as potential respiratory signals. A clustering algorithm was then used to search for the group of appropriate potential respiratory signals. The chosen signals were then normalized and averaged to form the final internal respiratory signal. Performance of the algorithm was tested in 50 4D CT data sets and results were compared with external signals from the real-time position management (RPM) system. Results: In almost all cases, the proposed algorithm generated internal respiratory signals that visibly matched the external respiratory signals from the RPM system. On average, the end inspiration times calculated by the proposed algorithm were within 0.1 s of those given by the RPM system. Less than 3% of the calculated end inspiration times were more than one time frame away from those given by the RPM system. In 3 out of the 50 cases, the proposed algorithm generated internal respiratory signals that were significantly smoother than the RPM signals. In these cases, images sorted using the internal respiratory signals showed fewer artifacts in locations corresponding to the discrepancy in the internal and external respiratory signals. Conclusion: We developed a robust algorithm that generates internal respiratory signals from 4D CT images. In some cases, it even showed the potential to outperform the RPM system. The proposed algorithm is completely automatic and generally takes less than 2 min to process. It can be easily implemented into the clinic and can potentially replace the use of external surrogates.

TH-E-17A-01: Internal Respiratory Surrogate for 4D CT Using Fourier Transform and Anatomical Features

International Nuclear Information System (INIS)

Hui, C; Suh, Y; Robertson, D; Pan, T; Das, P; Crane, C; Beddar, S

2014-01-01

Purpose: To develop a novel algorithm to generate internal respiratory signals for sorting of four-dimensional (4D) computed tomography (CT) images. Methods: The proposed algorithm extracted multiple time resolved features as potential respiratory signals. These features were taken from the 4D CT images and its Fourier transformed space. Several low-frequency locations in the Fourier space and selected anatomical features from the images were used as potential respiratory signals. A clustering algorithm was then used to search for the group of appropriate potential respiratory signals. The chosen signals were then normalized and averaged to form the final internal respiratory signal. Performance of the algorithm was tested in 50 4D CT data sets and results were compared with external signals from the real-time position management (RPM) system. Results: In almost all cases, the proposed algorithm generated internal respiratory signals that visibly matched the external respiratory signals from the RPM system. On average, the end inspiration times calculated by the proposed algorithm were within 0.1 s of those given by the RPM system. Less than 3% of the calculated end inspiration times were more than one time frame away from those given by the RPM system. In 3 out of the 50 cases, the proposed algorithm generated internal respiratory signals that were significantly smoother than the RPM signals. In these cases, images sorted using the internal respiratory signals showed fewer artifacts in locations corresponding to the discrepancy in the internal and external respiratory signals. Conclusion: We developed a robust algorithm that generates internal respiratory signals from 4D CT images. In some cases, it even showed the potential to outperform the RPM system. The proposed algorithm is completely automatic and generally takes less than 2 min to process. It can be easily implemented into the clinic and can potentially replace the use of external surrogates

Software Technologies - 8th International Joint Conference, ICSOFT 2013 : Revised Selected Papers

NARCIS (Netherlands)

Cordeiro, José; van Sinderen, Marten J.

2014-01-01

The present book includes extended and revised versions of a set of selected papers from the 8th International Joint Conference on Software Technologies (ICSOFT 2013), which was co-organized by the Reykjavik University (RU) and sponsored by the Institute for Systems and Technologies of Information,

Conference Report: 6th Annual International Symposium on Regenerative Rehabilitation.

Science.gov (United States)

Loghmani, M Terry; Roche, Joseph A

2018-04-03

The 6th International Symposium on Regenerative Rehabilitation, hosted by the Alliance for Regenerative Rehabilitation Research and Training (AR 3 T), included a preconference meeting of institutional representatives of the International Consortium of Regenerative Rehabilitation, keynote talks from distinguished scientists, platform and poster presentations from experts and trainees, panel discussions and postconference workshops. The following priorities were identified: increasing rigor in basic, preclinical and clinical studies, especially the use of better controls; developing better outcome measures for preclinical and clinical trials; focusing on developing more tissue-based interventions versus cell-based interventions; including regenerative rehabilitation in curricula of professional programs like occupational and physical therapy; and developing better instruments to quantify rehabilitative interventions.

Recent progress and focuses of ichnology: Outline of the 14th International Ichnofabric Workshop

OpenAIRE

Ruo-Ying Fan; Yi-Ming Gong

2017-01-01

The 14th International Ichnofabric Workshop was held successfully in Taipei, China from April 29th to May 2nd. From the oral presentations, posters, intra- and post-workshop field trips, and workshop discussions, a few promising aspects of ichnological study can be outlined: (1) Ichnotaxonomy is, and will be the major endeavour of ichnologists, supplying important behavioural information for palaeontological studies, and also providing reasonable, objective, and convenient taxonomical framewo...

ASM Based Synthesis of Handwritten Arabic Text Pages

Directory of Open Access Journals (Sweden)

Laslo Dinges

2015-01-01

Full Text Available Document analysis tasks, as text recognition, word spotting, or segmentation, are highly dependent on comprehensive and suitable databases for training and validation. However their generation is expensive in sense of labor and time. As a matter of fact, there is a lack of such databases, which complicates research and development. This is especially true for the case of Arabic handwriting recognition, that involves different preprocessing, segmentation, and recognition methods, which have individual demands on samples and ground truth. To bypass this problem, we present an efficient system that automatically turns Arabic Unicode text into synthetic images of handwritten documents and detailed ground truth. Active Shape Models (ASMs based on 28046 online samples were used for character synthesis and statistical properties were extracted from the IESK-arDB database to simulate baselines and word slant or skew. In the synthesis step ASM based representations are composed to words and text pages, smoothed by B-Spline interpolation and rendered considering writing speed and pen characteristics. Finally, we use the synthetic data to validate a segmentation method. An experimental comparison with the IESK-arDB database encourages to train and test document analysis related methods on synthetic samples, whenever no sufficient natural ground truthed data is available.

ASM Based Synthesis of Handwritten Arabic Text Pages.

Science.gov (United States)

Dinges, Laslo; Al-Hamadi, Ayoub; Elzobi, Moftah; El-Etriby, Sherif; Ghoneim, Ahmed

2015-01-01

Document analysis tasks, as text recognition, word spotting, or segmentation, are highly dependent on comprehensive and suitable databases for training and validation. However their generation is expensive in sense of labor and time. As a matter of fact, there is a lack of such databases, which complicates research and development. This is especially true for the case of Arabic handwriting recognition, that involves different preprocessing, segmentation, and recognition methods, which have individual demands on samples and ground truth. To bypass this problem, we present an efficient system that automatically turns Arabic Unicode text into synthetic images of handwritten documents and detailed ground truth. Active Shape Models (ASMs) based on 28046 online samples were used for character synthesis and statistical properties were extracted from the IESK-arDB database to simulate baselines and word slant or skew. In the synthesis step ASM based representations are composed to words and text pages, smoothed by B-Spline interpolation and rendered considering writing speed and pen characteristics. Finally, we use the synthetic data to validate a segmentation method. An experimental comparison with the IESK-arDB database encourages to train and test document analysis related methods on synthetic samples, whenever no sufficient natural ground truthed data is available.

Proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013, Buenos Aires, Argentina, August 26, 2013)

NARCIS (Netherlands)

Borgström, J.; Luttik, B.

2013-01-01

This volume contains the proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and the 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013) which was held on 26th August, 2013 in Buenos Aires, Argentina, as an affiliated workshop of CONCUR 2013, the

6th International Conference on Paleoceanography

CERN Document Server

Mix, Alan

1999-01-01

This volume is one outcome of the 6th International Conference on Paleoceano­ graphy (ICP VI). The conference was held August 23-28, 1998 in Lisbon, Portugal. The meeting followed the traditional format of a small number of invited oral presentations complemented by a large number ofcontributed posters. Over 550 participants attended, representing thirty countries and nearly 450 posters were presented. The invited speakers addressed the main themes of the 5oral sessions. The session topics were: Polar-Tropical and Interhemisphere Linkages; Does the Ocean Cause, or Respond to, Abrupt Climatic Changes?; Biotic Responses to Major Paleoceanographic Changes; Past Warm Climates; and Innovations In Monitoring Ocean History. This is the first time in ICP history that the Conference Proceedings are published. The aim of the organisers with the publication of this book is two-fold: to provide a useful review of the field and to document the ideas/controversies raised during the con­ ference that may stimulate future ...

10th International Conference MISSI 2016

CERN Document Server

Choroś, Kazimierz; Siemiński, Andrzej

2017-01-01

Recent years have seen remarkable progress on both advanced multimedia data processing and intelligent network information systems. The objective of this book is to contribute to the development of multimedia processing and the intelligent information systems and to provide the researches with the essentials of current knowledge, experience and know-how. Although many aspects of such systems have already been under investigation, but there are many new that wait to be discovered and defined. The book contains a selection of 36 papers based on original research presented during the 10th International Conference on Multimedia & Network Information Systems (MISSI 2016) held on 14–16 September 2016 in Wrocław, Poland. The papers provide an overview the achievements of researches from several countries in three continents. The volume is divided into five parts: (a) Images and Videos - Virtual and Augmented Reality, (b) Voice Interactions in Multimedia Systems, (c) Tools and Applications, (d) Natural Languag...

5th International Robotic Sailing Conference

CERN Document Server

Finnis, James

2013-01-01

Robotic sailing offers the potential of wind propelled vehicles which are sufficiently autonomous to remain at sea for months at a time. These could replace or augment existing oceanographic sampling systems, be used in border surveillance and security or offer a means of carbon neutral transportation. To achieve this represents a complex, multi-disciplinary challenge to boat designers and naval architects, systems/electrical engineers and computer scientists.  Since 2004 a series of competitions in the form of the Sailbot, World Robotic Sailing Championship and Microtransat competitions have sparked an explosion in the number of groups working on autonomous sailing robots. Despite this interest the longest distance sailed autonomously remains only a few hundred miles. Many of the challenges in building truly autonomous sailing robots still remain unsolved. These proceedings present the cutting edge of work in a variety of fields related to robotic sailing. They will be presented during the 5th International...

Towards a consensus-based biokinetic model for green microalgae – The ASM-A

DEFF Research Database (Denmark)

Wágner, Dorottya Sarolta; Valverde Pérez, Borja; Sæbø, Mariann

2016-01-01

developed to predict microalgal growth. However, none of these models can effectively describe all the relevant processes when microalgal growth is coupled with nutrient removal and recovery from wastewaters. Here, we present a mathematical model developed to simulate green microalgal growth (ASM-A) using...... and substrate availability can introduce significant variability on parameter values for predicting the reaction rates for bulk nitrate and the intracellularly stored nitrogen state-variables, thereby requiring scenario specific model calibration. ASM-A was identified using standard cultivation medium...

Conference proceedings of the 4. international conference on CANDU fuel. V. 1,2

International Nuclear Information System (INIS)

1995-01-01

These proceedings contain the full texts of all 65 papers presented at the 4th International Conference on CANDU fuel. As such, they represent an update on the state-of-the-art in such important CANDU fuel topics as International Development Programs and Operating Experience with CANDU fuel, Performance Assessments and Fuel Behavior Modeling, Fuel Properties, Licensing and Accident Analyses for CANDU fuel, Design, Testing and Manufacturing, and Advanced Fuel Designs. The large number of papers required the use of parallel sessions for the first time at a CANDU Fuel Conference

Conference proceedings of the 4. international conference on CANDU fuel. V. 1,2

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

These proceedings contain the full texts of all 65 papers presented at the 4th International Conference on CANDU fuel. As such, they represent an update on the state-of-the-art in such important CANDU fuel topics as International Development Programs and Operating Experience with CANDU fuel, Performance Assessments and Fuel Behavior Modeling, Fuel Properties, Licensing and Accident Analyses for CANDU fuel, Design, Testing and Manufacturing, and Advanced Fuel Designs. The large number of papers required the use of parallel sessions for the first time at a CANDU Fuel Conference.

10th International Conference on Progress in Fourier Transform Spectroscopy

CERN Document Server

Keresztury, Gábor; Kellner, Robert

1997-01-01

19 plenary lectures and 203 poster papers presented at the 10th International Conference of Fourier Transform Spectroscopy in Budapest 1995 give an overview on the state-of-the art of this technology and its wide range of applications. The reader will get information on any aspects of FTS including the latest instrumental developments, e.g. in diode array detection, time resolution FTS, microscopy and spectral mapping, double modulation and two-dimensional FTS.

Editorial: Papers from the 7th International Conference on Dendrochronology - Cultural Diversity, Environmental Variability

Science.gov (United States)

Margaret S. Devall; Elaine K. Sutherland

2008-01-01

The 7th International Conference on Dendrochronology - Cultural Diversity, Environmental Variability was held in Beijing, China from 11 to 17 June 2006. The conference was organized and hosted by the Institute of Botany, Chinese Academy of Sciences (IB_CAS) in conjunction with the International Union of Forest Research Organizations (IUFRO) Working Group 5.01.07 (Tree-...

Support for U.S. Participants at the 16th International Congress on Catalysis

Energy Technology Data Exchange (ETDEWEB)

Wachs, Israel E. [Lehigh Univ., Bethlehem, PA (United States)

2017-01-17

The enclosed report highlights the travel grant awarded to offset the cost of foreign travel of several faculty and students to attend the 16th International Congress on Catalysis (ICC) held in Beijing, China, July 3-8, 2016.

Feature extraction for face recognition via Active Shape Model (ASM) and Active Appearance Model (AAM)

Science.gov (United States)

Iqtait, M.; Mohamad, F. S.; Mamat, M.

2018-03-01

Biometric is a pattern recognition system which is used for automatic recognition of persons based on characteristics and features of an individual. Face recognition with high recognition rate is still a challenging task and usually accomplished in three phases consisting of face detection, feature extraction, and expression classification. Precise and strong location of trait point is a complicated and difficult issue in face recognition. Cootes proposed a Multi Resolution Active Shape Models (ASM) algorithm, which could extract specified shape accurately and efficiently. Furthermore, as the improvement of ASM, Active Appearance Models algorithm (AAM) is proposed to extracts both shape and texture of specified object simultaneously. In this paper we give more details about the two algorithms and give the results of experiments, testing their performance on one dataset of faces. We found that the ASM is faster and gains more accurate trait point location than the AAM, but the AAM gains a better match to the texture.

The 14th International Workshops on Opportunistic Protists (IWOP 14).

Science.gov (United States)

Cushion, Melanie T; Limper, Andrew H; Porollo, Aleksey; Saper, Vivian E; Sinai, Anthony P; Weiss, Louis M

2018-05-03

The 14th International Workshops on Opportunistic Protists (IWOP-14) was held August 10-12, 2017 in Cincinnati, OH, USA. The IWOP meetings focus on opportunistic protists (OIs); for example, free-living amoebae, Pneumocystis spp., Cryptosporidium spp., Toxoplasma, the Microsporidia, and kinetoplastid flagellates. The highlights of Pneumocystis spp. research included the reports of primary homothallism for mating; a potential requirement for sexual replication in its life cycle; a new antigen on the surface of small asci; roles for CLRs, Dectin-1, and Mincle in host responses; and identification of MSG families and mechanisms used for surface variation. Studies of Cryptosporidia spp. included comparative genomics, a new cryopreservation method; the role of mucin in attachment and invasion, and epidemiological surveys illustrating species diversity in animals. One of the five identified proteins in the polar tube of Microsporidia, PTP4, was shown to play a role in host infection. Zebrafish were used as a low cost vertebrate animal model for an evaluation of potential anti-toxoplasma drugs. Folk medicine compounds with anti-toxoplasma activity were presented, and reports on the chronic toxoplasma infection provided evidence for increased tractability for the study of this difficult life cycle stage. Escape from the parasitophorus vacuole and cell cycle regulation were the topics of the study in the acute phase. © 2018 International Society of Protistologists.

Thermodynamic assessment of the LiF–ThF4–PuF3–UF4 system

NARCIS (Netherlands)

Capelli, E.; Benes, O.; Konings, R.J.M.

2015-01-01

The LiF–ThF4–PuF3–UF4 system is the reference salt mixture considered for the Molten Salt Fast Reactor (MSFR) concept started with PuF3. In order to obtain the complete thermodynamic description of this quaternary system, two binary systems (ThF4–PuF3 and UF4–PuF3) and two ternary systems

5th CIRP international conference on industrial product-service systems

CERN Document Server

2013-01-01

“An Industrial Product-Service System is characterized by the integrated and mutually  determined planning, development, provision and use of product and service shares including its immanent software components in Business-to-Business applications and represents a knowledge-intensive socio-technical system.” – Meier, Roy, Seliger (2010) Since the first conference in 2009, the CIRP International Conference on Industrial Product-Service Systems has become a well-established international forum for the review and discussion of advances, research results and industrial improvements. Researchers from all over the world have met at previous IPS² conferences in Cranfield (2009), Linköping (2010), Braunschweig (2011) and Tokyo (2012). In 2013, the 5th CIRP International Conference on Industrial Product-Service Systems is held in Bochum. Important topics of IPS² research presented at the conference are: planning and development, sustainability, business models, operation, service engineering, knowledge mana...

Assessment of crack-like flaws - Comparison of procedures in BS 7910, API 579-1/ASME FFS-1, RSE-M AND FITNET

International Nuclear Information System (INIS)

Chaudouet, A.

2007-01-01

Among all Fitness For Service Codes enabling to assess flaws in metallic structures and to evaluate their remaining life, new editions of the most important ones at the international level have been issued recently. The latest edition of BS 7910 in United Kingdom has been released in October 2005. In the USA, API and ASME have edited a new standard in 2007, API579-1/ASME FFS-1, dedicated to pressure equipment. In France, the rules concerning the of Light Water Reactors, RSE-M, have been updated in 2005. Finally, in Europe, the FITNET network is writing a document based on BS 7910 but extended with the most recent results in this domain. Rules given in these documents to assess crack-like flaws with respect to fracture and fatigue propagation are presented. They are compared in order to point out the most interesting aspects of each ones and to identify those which could be generalized. An example assessed with the above mentioned 'Codes' enlightens the differences in the results with respect to the 'Code' used. (author) [fr

76 FR 37649 - Safety Zone; Northern California Annual Fireworks Events, July 4th Fireworks Display

Science.gov (United States)

2011-06-28

... Zone; Northern California Annual Fireworks Events, July 4th Fireworks Display AGENCY: Coast Guard, DHS... annual July 4th Fireworks Display (Tahoe City 4th of July Fireworks Display). This action is necessary to... INFORMATION: The Coast Guard will enforce the safety zone for the annual Tahoe City 4th of July Fireworks in...

230,232Th in milk, meat, and grain in Korea

International Nuclear Information System (INIS)

Lin, Xiujing; Choi, Minseok; Kim, Wan; Kang, Heedong; Doh, Sihhong; Kim, Dosung; Kim, Changkyu

2004-01-01

The concentrations of natural radioisotopes 230 Th and 232 Th in Korean foods were measured by the method of calcium oxalate co-precipitation in addition to the conventional anion-exchange method and alpha spectroscopic measurement. The 230 Th concentrations (mBq/kg-fresh) in Korean foods were found to be as follows: milk 0.14-2.45, pork 2.98-8.97, beef 1.94-9.80, chicken 1.22-13.0, rice 0.43-2.35, wheat 0.53-14.4, and soybeans, 8.44-91.6. The 232 Th concentrations (mBq/kg-fresh) in Korean foods were found to be as follows: milk 0.01-2.46, pork 0.28-9.32, beef 1.02-5.34, chicken 0.56-4.98, rice 0.32-2.54, wheat 0.53-20.0, and soybeans, 2.30-42.2. The annual internal dose of Th was also estimated. The annual internal dose of 230 Th and 232 Th in milk was about 0.006 μSv/yr and much lower than that of other countries because of the low intake of milk in Korea compared to other countries. The annual internal dose of 230 Th and 232 Th in the rice was about 0.043 μSv/yr and highest because rice is the staple food of Koreans. (author)

Electronic structure and magnetic properties of the ThCo4B compound

International Nuclear Information System (INIS)

Benea, D.; Pop, V.; Isnard, O.

2008-01-01

Detailed theoretical investigations of the electronic and magnetic properties of the newly discovered ThCo 4 B compound have been performed. The influence of the local environment on the magnitude of the Co magnetic moments is discussed by comparing the magnetic and electronic properties in the ThCo 4 B, YCo 4 B and ThCo 5 systems. All theoretical investigations of the electronic and magnetic properties have been done using the Korringa-Kohn-Rostoker (KKR) band-structure method in the ferromagnetic state. Very good agreement of the calculated and the experimental magnetic moments is obtained. Larger exchange-splitting is observed on the 2c site which carries by far the largest magnetic moment. Comparison of the band structure calculation for ThCo 5 and ThCo 4 B reveals that the presence of boron in the Co 6i site environment induces a broadening of the electronic bands as well as a significant reduction of the exchange-splitting and a diminution of the DOS at the Fermi level. These differences are attributed to the hybridization of the boron electronic states to the cobalt 3d ones. The calculated magnetic moment is 1.94μ B /formula unit. A large difference on the magnetic moment magnitude of the two Co sites is observed since 1.30 and 0.27μ B /atom are calculated for the 2c and 6i sites, respectively. The orbital contribution is found to differ by almost an order of magnitude on both cobalt sites. The Co magnetic moment is much smaller in the ThCo 4 B than in the YCo 4 B or RCo 4 B (where R is a rare earth) isotypes evidencing the major role played by the Th-Co bands on the electronic properties

ASM-Triggered Too Observations of Kilohertz Oscillations in Three Atoll Sources

Science.gov (United States)

Kaaret, P.; Swank, Jean (Technical Monitor)

2000-01-01

Three Rossi Timing Explorer (RXTE) observations were carried out for this proposal based on target of opportunity triggers derived from the All-Sky Monitor (ASM) on RXTE. We obtained short observations of 4U1636-536 (15ks) and 4U1735-44 (23ks) and a longer observation of 4U0614+091 (117ks). Our analysis of our observations of the atoll neutron star x-ray binary 4U1735-44 lead to the discovery of a second high frequency quasiperiodic oscillation (QPO) in this source. These results were published in the Astrophysical Journal Letters. The data obtained on the source 4U0614+091 were used in a comprehensive study of this source, which will be published in the Astrophysical Journal. The data from this proposal were particularly critical for that study as they lead to the detection of the highest QPO frequency every found in the x-ray emission from an x-ray binary which will be important in placing limits on the equation of state of nuclear matter.

Distribution of Th-230 and Th-228 in food (I)

Energy Technology Data Exchange (ETDEWEB)

Kang, Hee Dong; Kim, Wan; Lim, X. J.; Choi, M. S.; Kim, C. J.; Zheng, Y. Z. [Kyungpook National Univ., Daegu (Korea, Republic of); Kim, Do Sung [Daegu Univ., Daegu (Korea, Republic of)

2003-03-15

Natural radioisotopes contained in foods can enter the human body by ingestion and contribute to internal doses to the population. It is necessary to measure the concentration of natural radioisotopes especially thorium in Korean foods and estimate the internal doses. In this study, we have established the thorium measuring process based on the thorium extraction chemical process and alpha spectroscopic method. The concentration of Th-228, Th-230 and Th-232 in Korean milk, meats(pork, beef and chicken) and grain (wheat, bean and rice) are measured and internal doses are estimated.

International collaborative study for the calibration of proposed International Standards for thromboplastin, rabbit, plain and for thromboplastin, recombinant, human, plain

DEFF Research Database (Denmark)

van den Besselaar, A M H P; Chantarangkul, V; Angeloni, F

2018-01-01

BACKGROUND: The availability of International Standards for thromboplastin is essential for the calibration of routine reagents and hence the calculation of the International Normalized Ratio (INR). Stocks of the current 4(th) International Standards are running low. Candidate replacement materia......) international standard (rTF/09). The candidate materials have been accepted by WHO as the 5(th) International Standards for thromboplastin, rabbit plain, and thromboplastin, recombinant, human, plain. This article is protected by copyright. All rights reserved.......BACKGROUND: The availability of International Standards for thromboplastin is essential for the calibration of routine reagents and hence the calculation of the International Normalized Ratio (INR). Stocks of the current 4(th) International Standards are running low. Candidate replacement materials...... have been prepared. This report describes the calibration of the proposed 5(th) International Standards for thromboplastin, rabbit, plain (coded RBT/16) and for thromboplastin, recombinant, human, plain (coded rTF/16). METHODS: An international collaborative study was carried out for the assignment...

Effectiveness of oxfendazole against early and later 4th-stage Strongylus vulgaris in ponies.

Science.gov (United States)

Slocombe, J O; McCraw, B M; Pennock, P; Ducharme, N G; Baird, J D

1986-03-01

Twenty pony foals (reared worm free), 6.5 to 10 weeks of age, were inoculated with Strongylus vulgaris and allocated to 5 groups, each with 4 foals. One week after inoculation, 1 group of 4 foals was given oxfendazole (OFZ) at a dosage rate of 10 mg/kg of body weight, another group was given 2 such treatments 48 hours apart, and a 3rd group was given a placebo. All treatments were administered by stomach tube. Three weeks later, foals were euthanatized and necropsied in a test for efficacy against early 4th-stage larvae. Oxfendazole was 80% and 94.9% effective against early 4th-stage S vulgaris with 1 and 2 doses, respectively. A 4th group of 4 foals was given 2 treatments of OFZ, 48 hours apart, about 8 weeks after inoculation, and a 5th group was given a placebo. These foals were euthanatized and necropsied 5 weeks after treatment in a test for efficacy against later 4th-stage larvae. Two doses of OFZ were 96.6% effective against later 4th-stage larvae.