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Sample records for arylsulfonates

  1. Compensation effect in reactions between trans-4,4'-dinitrostilbene oxide and arylsulfonic acids

    Science.gov (United States)

    Shpan'ko, I. V.; Sadovaya, I. V.

    2016-12-01

    The effect structure and temperature have on the rate and free activation energy of reactions between trans-4,4'-dinitrostilbene oxide and Y-substituted arylsulfonic acids YC6H4SO3H in a mixture of dioxane with 1,2-dichloroethane (7: 3 vol/vol) at 265, 281, and 298 K is studied. It is found that as a result of the nonadditivity of the joint effect of substituents Y and temperature on the rate of the process of oxirane ring opening, the cross reaction series exhibits isoparametric properties in the aspect of enthalpy-entropy compensation. This allows the experimental determination of an isoparametric point with respect to the constant of substituent Y (σY IP= 0.52), in which activation entropy Δ S ≠ = 0 and free activation energy Δ G ≠ do not depend on temperature (Δ G ≠ = Δ H ≠), and to conduct the transition through this point with inversion of the order of the effect temperature has on the value of Δ G ≠ as a result of reversing the sign of Δ S ≠: in the series Y (σY) = 4-OCH3 (-0.27), 4-CH3 (-0.17), H (0), 4-Cl (0.23), and 3-NO2 (0.71), the values of Δ S ≠ (J/(mol K)) are-140,-119,-85,-42, and 44, respectively. The possibility of using isoparametric points as quantitative mechanistic criteria is demonstrated.

  2. One-step synthesis of α,β-unsaturated arylsulfones by a novel multicomponent reaction of aromatic aldehydes,chloroacetonitrile, benzenesulfinic acid sodium salt

    Institute of Scientific and Technical Information of China (English)

    Lei Zhang; Mao Hua Ding; Hong Yun Guo

    2012-01-01

    A new and green method for the synthesis of α,β-unsaturated arylsulfones had been achieved through the condensation of aromatic aldehydes,chloroacetonitrile,benzenesulfinic acid sodium salt in the presence of 1-butyl-3-methyl imidazolium hydroxide ([bmim]OH) in EtOH under reflux.The ionic liquid was recovered and recycled for subsequent reactions.The advantages of this protocol were non-toxic,easy work-up and good yields.

  3. Modification methods for poly(arylsulfone) membranes: A mini-review focusing on surface modification

    NARCIS (Netherlands)

    Nady, N.; Franssen, M.C.R.; Zuilhof, H.; Mohy Eldin, M.S.; Boom, R.M.; Schroën, C.G.P.H.

    2011-01-01

    Surface modification of membranes is thought to be equally important to the membrane industry as membrane material and process development; surface functionalization has already become a key technology, the major aims being performance improvement (flux and selectivity) by reduction of unwanted prot

  4. A Facile and Efficient Synthesis of Arylsulfonates and Arylsulfonyl Hydrazides under Solvent Free Conditions

    Institute of Scientific and Technical Information of China (English)

    ZHAO,Na; WANG,Yu-Lu; WANG,Jin-Ye

    2004-01-01

    @@ Organosulfur compounds are useful materials and most of them have pharmacological properties. The sulfonic esters are important intermediates in organic synthesis and used as acaricides and thermal recording materials. The sulfonyl hydrazides are valuable as inhibitors, agrochemical fungicides, insecticides and photographic images. Some methods have been reported for preparing these compounds to date. Usually, these reactions were carried out in organic solvent[1,2]such as pyridine and DMF. Even up-to date solid-phase synthesis requires solvent. What's more, they have other drawbacks including long reaction time, producing much wastes and by-products, tedious experimental procedure.

  5. Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity.

    Science.gov (United States)

    Elias, Paula Regina; Coelho, Gleicekelly Silva; Xavier, Viviane Flores; Sales Junior, Policarpo Ademar; Romanha, Alvaro José; Murta, Silvane Maria Fonseca; Carneiro, Claudia Martins; Camilo, Nilton Soares; Hilário, Flaviane Francisco; Taylor, Jason Guy

    2016-10-10

    A series of novel xylitan derivatives derived from xylitol were synthesized using operationally simple procedures. A xylitan acetonide was the key intermediate used to prepare benzoate, arylsulfonate esters and 1,2,3-triazole derivatives of xylitan. These compounds were evaluated for their in vitro anti-Trypanosoma cruzi activity against trypomastigote and amastigote forms of the parasite in T. cruzi-infected cell lineages. Benznidazole was used as positive control against T. cruzi and cytotoxicity was determined in mammalian L929 cells. The arylsulfonate xylitan derivative bearing a nitro group displayed the best activity of all the compounds tested, and was slightly more potent than the reference drug benznidazole. The importance of the isopropylidene ketal moiety was established and the greater lipophilicity of these compounds suggests enhancement in cell penetration.

  6. Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity

    Directory of Open Access Journals (Sweden)

    Paula Regina Elias

    2016-10-01

    Full Text Available A series of novel xylitan derivatives derived from xylitol were synthesized using operationally simple procedures. A xylitan acetonide was the key intermediate used to prepare benzoate, arylsulfonate esters and 1,2,3-triazole derivatives of xylitan. These compounds were evaluated for their in vitro anti-Trypanosoma cruzi activity against trypomastigote and amastigote forms of the parasite in T. cruzi-infected cell lineages. Benznidazole was used as positive control against T. cruzi and cytotoxicity was determined in mammalian L929 cells. The arylsulfonate xylitan derivative bearing a nitro group displayed the best activity of all the compounds tested, and was slightly more potent than the reference drug benznidazole. The importance of the isopropylidene ketal moiety was established and the greater lipophilicity of these compounds suggests enhancement in cell penetration.

  7. Elaboration de membranes pour piles a combustible par extrusion

    OpenAIRE

    Chabert, France

    2004-01-01

    The aim of these studies was to process membranes by extrusion to be used in fuel cells. The functional polymers used are generally processed by polluting techniques like casting-evaporation, which are not easily transposable on industrial scale. Extrusion is a widely used shaping operation in the polymer processing industry. However, extrusion had not been used until now for arylsulfonic ionic polymers. In order to avoid any risk of degradation of the polymer during extrusion, it was necessa...

  8. Novel chemistry of alpha-tosyloxy ketones: applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries

    DEFF Research Database (Denmark)

    Nicolaou, K C; Montagnon, T; Ulven, T;

    2002-01-01

    -tosyloxy ketones are engaged by "hard" versus "soft" nucleophiles. The accessibility and site-selectivity of the chemistry demonstrated herein offer the promise of an expanded use for this moiety in solid-phase library construction, in particular, and in the field of organic synthesis, in general......., and oxidation sequence, and ketones by direct exposure to arylsulfonic acids in the presence of diacetoxy iodobenzene. Reaction of these substrates with O-, S-, or N-centered nucleophiles leads to incorporation of the nucleophile with concomitant expulsion of the sulfonate, while exposure to bis-functional...

  9. Biostimulation of Oil Sands Process-Affected Water with Phosphate Yields Removal of Sulfur-Containing Organics and Detoxification.

    Science.gov (United States)

    Quesnel, Dean M; Oldenburg, Thomas B P; Larter, Stephen R; Gieg, Lisa M; Chua, Gordon

    2015-11-01

    The ability to mitigate toxicity of oil sands process-affected water (OSPW) for return into the environment is an important issue for effective tailings management in Alberta, Canada. OSPW toxicity has been linked to classical naphthenic acids (NAs), but the toxic contribution of other acid-extractable organics (AEOs) remains unknown. Here, we examine the potential for in situ bioremediation of OSPW AEOs by indigenous algae. Phosphate biostimulation was performed in OSPW to promote the growth of indigenous photosynthetic microorganisms and subsequent toxicity and chemical changes were determined. After 12 weeks, the AEO fraction of phosphate-biostimulated OSPW was significantly less toxic to the fission yeast Schizosaccharomyces pombe than unstimulated OSPW. Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) analysis of the AEO fraction in phosphate-biostimulated OSPW showed decreased levels of SO3 class compounds, including a subset that may represent linear arylsulfonates. A screen with S. pombe transcription factor mutant strains for growth sensitivity to the AEO fraction or sodium dodecylbenzenesulfonate revealed a mode of toxic action consistent with oxidative stress and detrimental effects on cellular membranes. These findings demonstrate a potential algal-based in situ bioremediation strategy for OSPW AEOs and uncover a link between toxicity and AEOs other than classical NAs.