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Sample records for arterias uterina umbilical

  1. EMBOLIZACIÓN DE ARTERIAS UTERINAS EN EL TRATAMIENTO DE MIOMAS UTERINOS SINTOMÁTICOS

    OpenAIRE

    Loyola Z,Soledad; Fava R,Mario; Macaya R,Rodrigo; MENESES Q,LUIS

    2007-01-01

    Los miomas uterinos pueden ser causa de menstruaciones abundantes y prolongadas, de síntomas por compresión de órganos vecinos e infertilidad. La embolización de arterias uterinas es una terapia mínimamente invasiva que se ha constituido en una alternativa terapéutica a la histerectomía y la miomectomía múltiple, para el tratamiento de miomas uterinos sintomáticos, en mujeres que no desean fertilidad futura. Esta consiste en ocluir ambas arterias uterinas mediante partículas, con el objetivo ...

  2. Reembolización de arterias uterinas por hemorragia posparto en una segunda gestación

    OpenAIRE

    López V,Nuria; Vegas G,Gabriel; Arrieta B,Sara; Iglesias S,Carlos; González G,Antonio

    2012-01-01

    La hemorragia posparto es la principal causa de muerte obstétrica. Presentamos el caso de una gestación y parto normales tras la embolización bilateral de ambas arterias uterinas, por hemorragia posparto en la gestación anterior. La paciente requirió de una nueva embolización bilateral de arterias uterinas en esta segunda gestación con buen resultado obstétrico. La embolización arterial pélvica en el manejo de la hemorragia posparto refractaria al tratamiento médico, permite en ocasiones evit...

  3. Tabaquismo materno: impacto sobre el neonato, placenta y reactividad de la arteria umbilical

    OpenAIRE

    Morales, Silvina; Iveli, María Florencia; Rimorini, Laura; Roldán Palomo, Rocío; Enrique, Nicolás; Salemme, Silvia; Cecotti, Norma; Rebolledo, Alejandro; Apezteguia, María; Milesi, Verónica

    2008-01-01

    Introducción: el fumar tabaco durante el embarazo aumenta los riesgos en la salud materno-infanto juvenil provocando múltiples alteraciones atribuidas a la nicotina y al monóxido de carbono producidos por el cigarrillo. Objetivos: estudiar las consecuencias del tabaquismo materno sobre el recién nacido (RN), la placenta y la respuesta contráctil a la nicotina de la arteria umbilical (AU) "in vitro". Metodología: dos grupo...

  4. Gases en sangre de arteria umbilical de neonatos a término en altura

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    Wilfredo Villamonte

    Full Text Available Con el objetivo de determinar los valores normales de gases en sangre en la arteria umbilical de neonatos a término a 3400 m de altitud se hizo un estudio transversal, realizado en la sangre de la arteria umbilical de 300 neonatos a término, adecuados para la edad gestacional y cuyo parto se dio entre enero de 2010 a diciembre de 2011 en el Hospital Nacional Adolfo Guevara Velazco de EsSalud (Cusco, Perú. Se encontró que la media del pH de neonatos sanos a término fue de 7,33 ± 0,07, los valores para los percentiles 5 y 95 fueron 7,18 y 7,40 respectivamente. En conclusión, se han construido las tablas con los percentiles 5 al 95 para el pH, pO2, pCO2, SO2, p50, exceso de bases y HCO3, de la arteria umbilical de neonatos a término a 3400 m de altitud

  5. ¿Tanta importancia tiene pasar por alto la arteria umbilical única?: Comentarios a partir de una sentencia judicial

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    A. Ortega Pérez

    2004-07-01

    Full Text Available El Tribunal Supremo ha condenado a varios obstetras por informar que el cordón umbilical tenía los tres vasos, desactivando así la búsqueda de enfermedades fetales que la arteria umbilical única (AUU habría desencadenado. La condena será éticamente correcta si la AUU está realmente asociada a tales enfermedades. En la población general se detecta un caso de AUU en cada 320 fetos estudiados ecográficamente. En el 68 % de esas detecciones se tratará de un hallazgo aislado, pero aún así aumenta el riesgo de parto prematuro, de peso bajo y de mortalidad perinatal. Por otra parte, el 17 % de estos fetos tendrán, además de la arteria única, cromosomopatías y el 31 % malformaciones anatómicas. Concluyendo, la AUU es realmente un marcador cardinal de riesgo de trastornos fetales, que debe buscarse activamente durante el seguimiento ecográfico del embarazo.

  6. ¿Tanta importancia tiene pasar por alto la arteria umbilical única?: Comentarios a partir de una sentencia judicial Does ignoring the single umbilical artery have so much importance?: Commentaries concerning a judicial sentence

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    A. Ortega Pérez

    2004-07-01

    Full Text Available El Tribunal Supremo ha condenado a varios obstetras por informar que el cordón umbilical tenía los tres vasos, desactivando así la búsqueda de enfermedades fetales que la arteria umbilical única (AUU habría desencadenado. La condena será éticamente correcta si la AUU está realmente asociada a tales enfermedades. En la población general se detecta un caso de AUU en cada 320 fetos estudiados ecográficamente. En el 68 % de esas detecciones se tratará de un hallazgo aislado, pero aún así aumenta el riesgo de parto prematuro, de peso bajo y de mortalidad perinatal. Por otra parte, el 17 % de estos fetos tendrán, además de la arteria única, cromosomopatías y el 31 % malformaciones anatómicas. Concluyendo, la AUU es realmente un marcador cardinal de riesgo de trastornos fetales, que debe buscarse activamente durante el seguimiento ecográfico del embarazo.The Spanish Supreme Court has condemned several obstetricians after having informed that the umbilical cord of a fetus had the three vessels, therefore deactivating the search for fetal diseases that the single umbilical artery (SUA would have provoked. The sentence will be ethically correct only if SUA is really associated with such diseases. SUA is found in about 1 out of every 320 fetuses studied sonographically. In 68% of them, it will be an isolated finding, although it will increase the risks of premature delivery, low birthweight, and perinatal mortality. On the other hand, 17% of these fetuses will have, besides SUA, chromosomal alterations, and 31 % of them, structural malformations. In conclusion, SUA is an important marker of fetal disorders, and it has to be actively searched for during the ultrasonographic monitoring of the gestation.

  7. Gravid med spontan ruptur af arteria uterina

    DEFF Research Database (Denmark)

    Jònsdòttir, Fjòla; Pinborg, Anja; Wilken-Jensen, Charlotte

    2014-01-01

    Pregnant women with acute abdominal pain are a clinical challenge. We present a rare but potential life-threatening condition of a pregnant woman with acute abdominal pain. The woman was in gestational week 37 with severe abdominal pain and was admitted to the labour ward. She became haemo......-dynamic instable 24 hours after vaginal delivery, and emergency laparotomi revealed a spontaneous rupture of the right uterine artery. Spontaneous rupture of the uterine artery is rare but should be considered as a possible cause of acute abdominal pain in pregnant women....

  8. Uso do Verapamil em Gestantes Hipertensas Crônicas: análise do Fluxo das Artérias Uterinas e Umbilical Use of Verapamil in Chronic Hypertensive Pregnant Women: flow Analysis of Uterine Arteries and Umbilical Artery

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    Marcus Jose do Amaral Vasconcellos

    2000-06-01

    Full Text Available Objetivo: este trabalho, utilizando verapamil, um bloqueador dos canais lentos de cálcio, constituiu ensaio clínico randomizado, duplo-cego e placebo controlado, e objetivou procurar variação do fluxo uteroplacentário e fetoplacentário durante uso oral crônico do fármaco em gestantes com hipertensão crônica leve para moderada. Métodos: 123 pacientes divididas em dois grupos: grupo estudo (n = 61, submetidas a 240 mg/dia de verapamil, e grupo controle (n = 62, submetidas ao placebo. As pacientes randomizadas em grupos de quatro utilizaram a medicação ou placebo durante trinta dias. Um exame do fluxo das artérias uterinas e da artéria umbilical pela dopplervelocimetria foi registrado. Pelo cálculo da média e desvio padrão, foram comparados os valores dos índices de resistência (IR e pulsatilidade (IP e da relação sístole/diástole (A/B das artérias em estudo após administração dos comprimidos. Resultados: o grupo verapamil apresentou os seguintes valores médios para as artérias uterinas: IR = 0,82 (0,28, IP de 1,06 (0,12 e A/B de 2,42 (0,51. O grupo placebo mostrou: IR de 0,75 (0,35, IP de 1,00 (0,18 e A/B de 2,30 (0,38. Quando analisada a artéria umbilical, os valores foram para o grupo verapamil: IR = 0,73 (0,12, IP = 1,04 (0,13 e A/B = 2,94 (0,32. No grupo placebo, IR = 0,70 (0,14, IP = 1,03 (0,07 e A/B = 3,02 (0,78. A análise estatística das diferenças das médias por meio da razão F mostrou não haver diferença entre os dois grupos avaliados. Conclusão: este trabalho referenda o uso do verapamil entre gestantes com hipertensão crônica (leve para moderada, pois não oferece prejuízos no fluxo uteroplacentário e fetoplacentário.Purpose: this study, using verapamil, a slow calcium channel blocker, was a randomized, clinical, double blind and placebo controlled trial, whose objective was to observe if there was a uteroplacental and fetoplacental flow variation during its chronic oral use. Methods: 123

  9. LIGADURA DE LAS ARTERIAS ILIACAS INTERNAS (HIPOGASTRICAS) EN CIRUGIA OBSTETRICA

    OpenAIRE

    Torres A,Octavio; Bueno N,Francisco; González R,Reinaldo; Bronda M.,Alessandro

    2002-01-01

    Se presentan diez casos de ligadura de arteria hipogástrica de causa obstétrica. Describimos la técnica, se analiza las indicaciones, riesgos y complicaciones quirúrgicas. El procedimiento fue efectivo en controlar la hemorragia en todos los casos. La principal indicación fue la inercia uterina.

  10. Efeito do sulfato de magnésio sobre o índice de pulsatilidade das artérias uterinas, umbilical e cerebral média fetal de acordo com a persistência da incisura protodiastólica da artéria uterina na pré-eclâmpsia grave Effect of magnesium sulfate on pulsatility index of uterine, umbilical and fetal middle cerebral arteries according to the persistence of bilateral diastolic notch of uterine arteries in patients with severe preeclampsia

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    Alex Sandro Rolland Souza

    2009-02-01

    Full Text Available OBJETIVO: avaliar o efeito do sulfato de magnésio sobre o índice de pulsatilidade (IP das artérias uterinas, umbilicais e cerebral média fetal, de acordo com a persistência ou não da incisura protodiastólica bilateral das artérias uterinas na pré-eclâmpsia grave. MÉTODOS: foi desenvolvido um estudo do tipo coorte, incluindo 40 gestantes com pré-eclâmpsia grave, das quais 23 apresentavam incisura protodiastólica bilateral e 17, incisura ausente/unilateral. As pacientes foram submetidas a doplervelocimetria antes e depois de 20 minutos da administração intravenosa de 6 g do sulfato de magnésio. O exame foi realizado com a paciente em posição semi-Fowler, obtendo-se os sonogramas durante a inatividade fetal, em períodos de apneia e ausência de contrações uterinas. Todos os exames foram realizados por dois pesquisadores, considerando a média como resultado final. A comparação dos IP antes e depois do sulfato de magnésio em cada grupo foi realizada pelo teste de Wilcoxon. A diferença das duas medidas (antes e depois do sulfato de magnésio foi comparada entre os grupos (incisura bilateral e incisura ausente/unilateral utilizando-se o teste de Mann-Whitney. RESULTADOS: houve um aumento significativo da frequência cardíaca materna e uma diminuição da pressão arterial materna e da mediana dos IP das duas artérias uterinas e da artéria cerebral média fetal depois da utilização do sulfato de magnésio em ambos os grupos. Houve redução significativa do IP da artéria uterina esquerda e da artéria umbilical apenas no grupo com incisura protodiastólica unilateral/ausente. No entanto, não foram encontradas diferenças significativas em relação ao IP da artéria uterina direita e relação umbilical/cerebral antes e depois do sulfato de magnésio em cada grupo. Não se encontrou diferença entre os grupos, antes e depois do sulfato de magnésio, para nenhum dos desfechos estudados. CONCLUSÕES: após a administra

  11. Malformación arterio-venosa uterina y hemorragia obstétrica: diagnóstico y manejo en tres casos clínicos

    OpenAIRE

    Hasbun H,Jorge; Palavecino R,Patricio; Segura H,Patricia; Chavez R,Ignacio; Burgos S,Nelson; Tobar A,Hermógenes; Aliaga Q,Adolfo

    2014-01-01

    Las malformaciones vasculares uterinas son muy infrecuentes y se presentan asociadas a metrorragia con riesgo vital. Su incidencia no es conocida porque las series son de pocos casos. Presentamos tres pacientes con hemorragia obstétrica cuyo estudio diagnóstico con ultrasonido y angiografía, demostró malformación arteriovenosa uterina. En un caso, dada la extensión de la lesión, el tratamiento fue con embolización bilateral de arterias uterinas seguida de histerectomía. Otras dos pacientes, p...

  12. Complicaciones puerperales. Atonía uterina

    OpenAIRE

    Asensio Díaz, Ana

    2015-01-01

    Me decidí a tratar el tema de la atonía uterina en mi Trabajo de Fin de Grado porque, según la OMS, es la principal causa de las hemorragias puerperales, que a su vez son responsables de la mayor incidencia de mortalidad materna a nivel mundial. Definiremos la atonía uterina como la pérdida de tono uterino en el puerperio, que impide el proceso de involución uterina y se manifiesta mediante hemorragia vaginal excesiva y persistente y útero de consistencia blanda a la palpación. A lo largo ...

  13. RUPTURA UTERINA ESPONTANEA POR PLACENTA PERCRETA

    OpenAIRE

    2003-01-01

    La rotura uterina en un útero sin cicatriz previa, y temprano en el tercer trimestre, es un evento raro. Se expone el caso clínico de una paciente que se presenta con abdomen agudo, cursando embarazo de aproximadamente 25 semanas, se realiza laparotomía exploradora encontrando hemoperitoneo, feto y placenta libres en la cavidad peritoneal y útero roto en el fondo invadido por la placenta, que compromete epiplón mayor. Se realiza histerectomía y se confirma el diagnóstico con biopsia

  14. Rotura Uterina Espontánea en embarazo de segundo trimestre: presentación de un caso y revisión de la literatura

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    Airam Amoroso

    2013-09-01

    Full Text Available La rotura uterina se define como la solución de continuidad de la pared uterina. Es una complicación obstétrica poco frecuente y potencialmente letal para la madre y el feto, que ocurre generalmente durante el segundo o tercer trimestre de gestación, y que está asociada principalmente a la cirugía uterina previa, constituyendo así un desafío médico por su difícil diagnóstico diferencial y controversial manejo. Se presenta el caso de una paciente de 26 años de edad, con rotura espontánea de útero grávido de 18 semanas de gestación y antecedente de cicatriz uterina. Se realiza laparotomía exploradora obteniendo como hallazgo placenta y cordón umbilical unido a feto sin vida en cavidad abdominal, lo que confirma diagnóstico intraoperatorio. Spontaneous Uterine Rupture in Second Trimester of Pregnancy: Case report and Literature review Abstract Uterine rupture is a solution of continuity of the uterine wall. It is an uncommon and potentially lethal obstetric complication, for both mother and fetus, that mainly occurs during the second or third trimester of pregnancy, and that is mainly associated to previous uterine surgery, thus forming a medical challenge for its difficult differential diagnosis and controversial management. We report the case of a 26 years old patient with a spontaneous gravid uterine rupture, 18 weeks of gestation and cesarean scar background. Laparotomy is conducted finding both placenta and umbilical cord attached to no-living fetus in the abdominal cavity, which confirms intraoperative diagnosis.

  15. Umbilical Hernia

    Science.gov (United States)

    ... complicated umbilical hernia with liver cirrhosis and ascites. International Journal of Surgery. 2014;12:181. Cameron JL, et al. In: Current Surgical Therapy. 11th ed. Philadelphia, Pa.: Saunders Elsevier; ...

  16. Surface Alteration in Aging of Rat Tubae Uterinae Epithelium

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    Zekiye Suludere

    2012-12-01

    Full Text Available Objective: Aim of the study was evaluating arrangement of apical surface differentiation in cross-sections of tuba uterinae in different age groups by scanning electron microscope.Material and Methods: Six groups were created with 36 Wistar rat; 1st group: neonate (1th day (n=6, 2nd group: young (22nd day (n=6, 3rd group: prepubertal (4-6 week (n=6, 4th group: adult (10 week (n=6, 5th group: premenopausal (8 month (n=6, 6th group: old (18-20 month (n=6. Tissue samples examined with scanning electron microscope.Results: When surface differentiations of epithelial cells in tubae uterinae from birth to menopause were considered, it was determined that the cell with microvilli are first maturing cells and degenerated by ages first. It was observed that the ciliated cells are last maturing cells and subsisting as a mature cell during the postmenopausal period.Conclusion: Towards the menopause degeneration in microvillous cells together with lack of secretion may affect sperm nutrition adversely. The increase of ciliated cells in aging may be a physiological result related to the active role of cilia movement in the sperm and early embryo transport against a probable decrease in muscle contraction in aging.

  17. Trombosis de la arteria renal en un recién nacido. Presentación de un caso y revisión

    OpenAIRE

    Ana Lucía Torres; Javier Torres; Jorge Andrés Cifuentes

    2009-01-01

    Se describe un neonato que presenta cifras tensionales elevadas y ausencia de pulsos en miembros inferiores en su cuarto día de vida después de la colocación de un catéter umbilical arterial, evidenciando trombosis en arteria aorta y renal izquierda. Se realizó gammagrafía con MAG 3 que mostró exclusión renal izquierda y angioresonancia de aorta y renal izquierda. Se inició manejo con heparina no fraccionada y estreptoquinasa durante 6 horas. Se recuperó totalmente el compromiso en miembros i...

  18. Tratamiento híbrido de arteria subclavia derecha aberrante

    OpenAIRE

    Vargas S,Francisco; Mertens M,Renato; Sánchez C,Gonzalo; Bergoeing R,Michel; Kramer S,Albrecht; Mariné M,Leopoldo; Valdés E,Francisco

    2013-01-01

    Introducción: La arteria subclavia derecha aberrante es la malformación arterial más frecuente del arco aórtico. Su diagnóstico es habitualmente un hallazgo de estudios de imágenes solicitados por otras causas pero puede tener serias complicaciones si se obtiene en forma tardía. Caso clínico: Presentamos el caso de una mujer joven con diagnóstico de arteria subclavia lusoria dilatada sometida exitosamente a tratamiento híbrido electivo.

  19. Origen pulmonar anómalo de la arteria circunfleja en un paciente adulto

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    Ricardo L. Levin

    2009-01-01

    Full Text Available RESUMENEl origen anómalo de las arterias coronarias constituye una entidad poco frecuente y enpacientes adultos resulta excepcional el hallazgo de una arteria circunfleja naciendo desdela arteria pulmonar. Se presenta un caso de origen aberrante de la arteria circunfleja desdela rama derecha de la arteria pulmonar, detectado por métodos semiinvasivos (ecocardiogramatransesofágico y angiotomografía coronaria multicorte. Debido a las características clínicas del paciente, joven deportista, sintomático por angor, con prueba funcionalpositiva para isquemia y el origen pulmonar de la arteria circunfleja, se decidió efectuartratamiento quirúrgico con reimplante del ostium coronario en la aorta. La evoluciónposoperatoria resultó favorable.REV ARGENT CARDIOL 2009;77:524-526.

  20. Arteria sinuosa del colon: su importancia en la circulación colateral intestinal

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    Edgar Giovanni Corzo Gómez,

    2008-04-01

    Full Text Available La circulación colateral de la vascularización mesentéricaha sido bien descrita. La arteria Marginal o arteria deDrummond, se ubica paralela al borde mesentérico delintestino grueso, y el arco de Riolan, conecta la ramaizquierda de la arteria cólica media con la rama ascendentede la arteria cólica izquierda a través de una porción de laarteria Marginal. Recientemente Moskowitz y colabora-dores describieron la arteria mesentérica sinuosa, como unnuevo vaso colateral con grandes implicacionesquirúrgicas. El objetivo de este artículo es describir laimportancia clínica y quirúrgica de esta arteria.

  1. Umbilical hernia (image)

    Science.gov (United States)

    An umbilical hernia is a protrusion of the peritoneum and fluid, omentum, or a portion of abdominal organ(s) through the ... spontaneously without treatment by age 1 or 2. Umbilical hernias are usually painless and are common in infants.

  2. Trombosis de la arteria renal en un recién nacido. Presentación de un caso y revisión

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    Ana Lucía Torres

    2009-03-01

    Full Text Available Se describe un neonato que presenta cifras tensionales elevadas y ausencia de pulsos en miembros inferiores en su cuarto día de vida después de la colocación de un catéter umbilical arterial, evidenciando trombosis en arteria aorta y renal izquierda. Se realizó gammagrafía con MAG 3 que mostró exclusión renal izquierda y angioresonancia de aorta y renal izquierda. Se inició manejo con heparina no fraccionada y estreptoquinasa durante 6 horas. Se recuperó totalmente el compromiso en miembros inferiores, mejorando cifras tensionales a los pocos días. Estudios de seguimiento de función renal y crecimiento evidencian flujo de arteria renal izquierda y algo de función. Se describe mejoría con tratamiento anticoagulante y trombolítico de un riñón neonatal a pesar de sufrir isquemia prolongada.

  3. Trombosis de la arteria renal en un recién nacido. Presentación de un caso y revisión

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    Ana Lucía Torres

    2009-12-01

    Full Text Available Se describe un neonato que presenta cifras tensionales elevadas y ausencia de pulsos en miembros inferiores en su cuarto día de vida después de la colocación de un catéter umbilical arterial, evidenciando trombosis en arteria aorta y renal izquierda. Se realizó gammagrafía con MAG 3 que mostró exclusión renal izquierda y angioresonancia de aorta y renal izquierda. Se inició manejo con heparina no fraccionada y estreptoquinasa durante 6 horas. Se recuperó totalmente el compromiso en miembros inferiores, mejorando cifras tensionales a los pocos días. Estudios de seguimiento de función renal y crecimiento evidencian flujo de arteria renal izquierda y algo de función. Se describe mejoría con tratamiento anticoagulante y trombolítico de un riñón neonatal a pesar de sufrir isquemia prolongada.

  4. Perforación uterina y de colon por T de cobre

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    Iván Toribio- Membreño

    2005-01-01

    Full Text Available Se reporta el caso de una paciente de 36 años, con perforación uterina y del colon sigmoides con una Tcu colocada 14 años atrás, y que evolucionó en forma asintomática. El manejo requirió de histerectomía abdominal, con reparación de colon sigmoides y colostomía transversa temporal con evolución final satisfactoria. La perforación uterina por dispositivos intrauterinos (DIU, constituye una complicación poco frecuente, y puede acompañarse de perforación de otras vísceras en el 15%, de los casos principalmente del intestino.

  5. Brachiomedian artery (arteria brachiomediana revisited: a comprehensive review

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    David Kachlik

    2016-03-01

    Full Text Available This article reviews in detail the superficial brachiomedian artery (arteria brachiomediana superficialis, a very rare variant of the main arterial trunks of the upper limb. It branches either from the axillary artery or the brachial artery, descends superficially in the arm (similar to the course of the superficial brachial artery and continues across the cubital fossa, runs superficially in the forearm, approaches the median nerve and enters the carpal canal to reach the hand. It usually terminates in the superficial palmar arch. The first drawing was published, in 1830, and the first description was published, in 1844. Altogether, to our knowledge, only 31 cases of a true, superficial brachiomedian artery have been reported (Some cases are incorrectly reported as superficial brachioradiomedian artery or superficial brachioulnomedian artery. Based on a meta-analysis of known, available studies, the incidence is 0.23% in Caucasians and 1.48% in Mongolians. Knowing whether or not this arterial variant is present is important in clinical medicine and relevant for: The catheterization via the radial or ulnar artery; harvesting the vascular pedicle for a forearm flap based on the radial, ulnar or superficial brachiomedian arteries; the possible collateral circulation in cases of the arterial closure; and the surgical management of carpal tunnel syndrome. Its presence can elevate the danger of an injury to the superficially located variant artery or of an accidental injection.

  6. Alterações na gasometria de fetos aloimunizados após procedimento de transfusão intra-uterina

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    Nomura Roseli Mieko Yamamoto

    2003-01-01

    Full Text Available OBJETIVO: este estudo, realizado em gestações com aloimunização pelo fator Rh, tem como objetivo descrever as alterações gasométricas e do equilíbrio ácido-básico fetal antes e após transfusões intra-uterinas (TIU. MÉTODO: no período de junho de 2001 a outubro de 2001, antes e após a TIU em fetos de gestantes aloimunizadas, foram avaliados prospectivamente a gasometria e o equilíbrio ácido-básico no sangue da veia umbilical. As medidas foram realizadas em 8 amostras de sangue de 5 fetos. O sangue fetal foi obtido por cordocentese da veia umbilical antes e após TIU. Os resultados obtidos foram comparados com a expansão volêmica na TIU, a idade gestacional no procedimento, o peso fetal estimado pela ultra-sonografia e as variações da hemoglobina fetal (g/dL. RESULTADOS: em todos os casos foi observada queda nos valores do pH, com redução média de 0,09 (DP=0,02. A hemoglobina fetal apresentou aumento médio de 8,4 g/dL (DP=2,9 g/dL. Foi constatada também variação negativa da pO2 (média = -1,28 mmHg na concentração de HCO3_ (média = _2,25 mEq/l. Houve aumento da pCO2 (média = 3,2 mmHg e redução nos valores do excesso de bases (média = -3,75. CONCLUSÃO: a análise das gasometrias permite concluir que o procedimento de TIU acompanha-se de queda nos valores do pH de sangue de veia umbilical, demonstrando haver acidemia fetal relativa após o procedimento.

  7. Umbilical endometriosis associated with large umbilical hernia. Case report.

    Science.gov (United States)

    Stojanovic, M; Radojkovic, M; Jeremic, L; Zlatic, A; Stanojevic, G; Janjic, D; Mihajlovic, S; Dimov, I; Kostov, M; Zdravkovic, M; Stojanovic, M

    2014-01-01

    Umbilical endometriosis is a rare condition, usually following laparoscopic and surgical procedures involving the umbilicus.Spontaneous umbilical endometriosis occurring without any previous abdominal or uterine surgery is extremely rare. The maximal depth of penetration of the umbilical endometriosis described is up to fascial level. There have been only two cases of endometriosis reported arising within umbilical hernia. The authors report a case of a patient with spontaneous umbilical endometriosis associated with a large umbilical hernia, treated by surgical excision and mesh repair of the abdominal wall. To the best of our knowledge, this is the first described case of the association of umbilical endometriosis with a large umbilical hernia that requires prosthetic mesh repair of the abdominal wall defect.

  8. Umbilical arteriovenous malformation in a healthy neonate with umbilical hernia.

    Science.gov (United States)

    Marcelo Boglione, Mariano; D Alessandro, Pablo; Reusmann, Aixa; Rubio, Martín; Lipsich, José; Goldsmith, Gustavo

    2013-01-01

    We describe the case of a neonate with an umbilical hernia and persistent wet umbilicus. Examination revealed a pulsatile umbilical cord with palpable thrill. Doppler ultrasound suspected umbilical arteriovenous malformation and contrast-enhanced computed tomography was performed leading to a definitive diagnosis. Surgery was successfully performed on day 27.

  9. Umbilical Arteriovenous Malformation in a Healthy Neonate with Umbilical Hernia

    OpenAIRE

    2013-01-01

    We describe the case of a neonate with an umbilical hernia and persistent wet umbilicus. Examination revealed a pulsatile umbilical cord with palpable thrill. Doppler ultrasound suspected umbilical arteriovenous malformation and contrast-enhanced computed tomography was performed leading to a definitive diagnosis. Surgery was successfully performed on day 27.

  10. Tratamento dos Leiomiomas por Embolização das Artérias Uterinas

    Directory of Open Access Journals (Sweden)

    Messina Marcos de Lorenzo

    2001-01-01

    Full Text Available Objetivos: avaliar os resultados da embolização das artérias uterinas (EAU como tratamento do leiomioma uterino. Métodos: foram estudadas 18 mulheres com diagnóstico ultra-sonográfico de leiomioma uterino submetidas à EAU com partículas de álcool polivinílico (PVA. O acesso arterial foi realizado por punção da artéria femoral e a progressão do cateter foi monitorada até atingir seletivamente as artérias uterinas. A avaliação dos resultados foi realizada pelo estudo ultra-sonográfico antes e três meses após o procedimento. Foi realizado controle clínico evolutivo para avaliação das características menstruais e do volume uterino. Resultados: houve insucesso técnico em três casos por dificuldade de cateterização das artérias uterinas. O sangramento e a dismenorréia foram controlados no intervalo de três meses em 86 e 60% das pacientes, respectivamente. A média dos volumes uterinos iniciais foi de 381 cm³ e após 3 meses foi de 263 cm³. Houve redução média de 27,4% no volume uterino três meses após o tratamento. Três pacientes tiveram insuficiência ovariana clínica e laboratorial (20% dos casos. Conclusões: a EAU representa alternativa terapêutica para o tratamento dos leiomiomas uterinos. Em virtude do risco de insuficiência ovariana esse procedimento é reservado para pacientes com mais de 45 anos de idade ou com prole completa.

  11. Umbilical hernia repair - series (image)

    Science.gov (United States)

    Umbilical hernias are fairly common. They are obvious at birth and are caused by a small defect in ... surgically. In most cases, by age 3 the umbilical hernia shrinks and closes without treatment. The indications for ...

  12. Popeye Project: Hydraulic umbilical

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, K.G.; Williams, V.T.

    1996-12-31

    For the Popeye Project, the longest super-duplex hydraulic umbilical in the world was installed in the Gulf of Mexico. This paper reports on its selection and project implementation. Material selection addresses corrosion in seawater, water-based hydraulic fluid, and methanol. Five alternatives were considered: (1) carbon-steel with traditional coating and anodes, (2) carbon-steel coated with thermally sprayed aluminum, (3) carbon-steel sheathed in aluminum, (4) super-duplex, and (5) titanium. The merits and risks associated with each alternative are discussed. The manufacture and installation of the selected umbilical are also reported.

  13. Disección de arterias coronarias asociada con el consumo de cocaína

    OpenAIRE

    Guillermo Marchetti; Juan Arellano; Flavio Salvaggio; Luis Gariglio; Gabriel Pérez Baztarrica; Alejandro Botbol; Rafael Porcile

    2008-01-01

    La disección espontánea de arterias coronarias es en extremo rara y escasamente documentada en la bibliografía mundial. Una de las causas en pacientes jóvenes es la adicción a la cocaína. Se presenta el caso de un paciente con historia de consumo reciente de cocaína que ingresa derivado por infarto de miocardio para cinecoronariografía y angioplastia. En la cinecoronariografía se evidencia una disección espontánea de la arteria descendente anterior con flujo TIMI III. Debido al contexto clíni...

  14. Perforación uterina y de colon por T de cobre

    Directory of Open Access Journals (Sweden)

    Iván Toribio- Membreño

    2005-01-01

    Full Text Available Se reporta el caso de una paciente de 36 años, con perforación uterina y del colon sigmoides con una Tcu colocada 14 años atrás, y que evolucionó en forma asintomática. El manejo requirió de histerectomía abdominal, con reparación de colon sigmoides y colostomía transversa temporal con evolución final satisfactoria. La perforación uterina por dispositivos intrauterinos (DIU, constituye una complicación poco frecuente, y puede acompañarse de perforación de otras vísceras en el 15%, de los casos principalmente del intestino.We report the case of 36 years old female, with uterine and sigmoid colon perforation caused by a Tcu placed 14 years previously. She was asymptomatic. The management required an abdominal histerectomy and repair of the sigmoid colon, she also needed a temporary transverse colostomy with final satisfactory outcome. Uterine perforation by intrauterine devices, is an infrequent complication, in 15% of the cases it is associated with perforation of other internal organs, primarily the intestine.

  15. Sonography of the umbilical cord.

    Science.gov (United States)

    Dudiak, C M; Salomon, C G; Posniak, H V; Olson, M C; Flisak, M E

    1995-09-01

    Knowledge of the development, normal sonographic appearance, and potential abnormalities of the umbilical cord is important in fetal assessment. The umbilical cord can be visualized throughout most of gestation and is detectable sonographically soon after visualization of the fetal pole. The normal umbilical cord is 50-60 cm long and may coil as many as 40 times, usually to the left. Abnormalities in umbilical cord size, degree of coiling, attachment, and position can have important implications for the outcome of the pregnancy. Structural abnormalities of the umbilical cord such as single umbilical artery, knots, cysts, and tumors may be associated with fetal distress or malformations. Color Doppler ultrasound (US) is useful in the identification and evaluation of structural abnormalities of the cord. By allowing measurement of blood flow velocity in the umbilical artery, duplex Doppler US may provide additional information in the evaluation of intrauterine growth retardation and twin-twin transfusion syndrome.

  16. Umbilical metastases: current viewpoint

    Directory of Open Access Journals (Sweden)

    Egidi Federico

    2005-02-01

    Full Text Available Abstract Background Umbilical metastases from a malignant neoplasm, also termed Sister Mary Joseph's nodule, are not commonly reported in the English literature, and they have usually been considered as a sign of a poor prognosis for the patient. The present article reports on the current view point on umbilical metastasis besides discussing the epidemiology, clinical presentation, pathophysiology and treatment. Method A search of Pubmed was carried out using the term 'umblic*' and 'metastases' or metastasis' revealed no references. Another search was made using the term "Sister Joseph's nodule" or sister Joseph nodule" that revealed 99 references. Of these there were 14 review articles, however when the search was limited to English language it yielded only 20 articles. Articles selected from these form the basis of this report along with cross references. Results The primary lesions usually arise from gastrointestinal or genitourinary tract malignancies and may be the presenting symptom or sign of a primary tumour in an unknown site. Conclusion A careful evaluation of all umbilical lesions, including an early biopsy if appropriate, is recommended. Recent studies suggest an aggressive surgical approach combined with chemotherapy for such patients may improve survival.

  17. Fullterm pregnancy in umbilical hernia

    OpenAIRE

    2011-01-01

    While umbilical hernias frequently occur during pregnancy, the few reported cases of uterine or fibroid incarceration in ventral hernias during pregnancy all involved incisional abdominal wall defects from prior laparotomies and Cesarean sections; none involved umbilical hernias. We discuss the case of a 42-year-old well-developed, well-nourished grand multiparous woman (G8P7) with a huge umbilical hernia containing a 38-week gravid uterus, as well as her management and the avoidance of known...

  18. Caracterización hemodinámica doppler e inflamatoria de las preeclámpticas: análisis del efecto del tratamiento con parches de nitroglicerina

    OpenAIRE

    Reyna Villasmil,Eduardo

    2012-01-01

    De esta investigación prospectiva de la caracterización hemodinámica Doppler e inflamatoria de pacientes con preeclampsia y de un grupo control de embarazadas normotensas sanas, así como el análisis del efecto del tratamiento con parches de nitroglicerina en las preeclámpticas, se concluye que: Las preeclámpticas tiene valores significativamente más latos de velocimetría Doppler en las arterias uterinas, umbilical, renal fetal y hepática fetal y más bajos de la arteria cerebral media fetal co...

  19. Umbilical and portal vein calcification following umbilical vein catheterization

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, K.; Fendel, H.; Hartl, M.

    1989-07-01

    Calcifications of the umbilical vein and intrahepatic branches of the portal vein developed in a newborn who had inserted an umbilical vein catheter for 11 days postnatally. The calcified intrahepatic portal veins can still be demonstrated sonographically at the age of three years, whereby these calcifications were no longer detectable radiologically. (orig.).

  20. Katodisk beskyttelse av umbilicals

    OpenAIRE

    Mjølhus, Bjarte

    2008-01-01

    Ulike sider ved bruk av sinkbånd til korrosjonsbeskyttelse av karbonstål umbilical er evaluert. Det er utført litteraturstudie ved gjennomgang av tidligere rapporter, sammenligning av standarder og artikkelsøk. Langtidsforsøk med egne korrosjonsceller ble utført over 2 måneder for å undersøke korrosjonsbeskyttelse ved 4 ulike temperaturer. Det ble også gjort undersøkelser av korrosjonsbelegg i SEM for å undersøke og sammenligne med publiserte data. Åpen krets potensialet viste seg å ligge ...

  1. Rotura uterina en gestante con cesárea anterior tras maniobra de Kristeller: Reporte de caso

    OpenAIRE

    2014-01-01

    Antecedentes: La rotura uterina es una complicación rara (0,7%), pero grave en la práctica obstétrica. La cesárea previa es el factor predisponente más importante para este evento catastrófico. Su aparición espontánea es extremadamente rara, se estima que ocurre en 1 de 8000 a 1 de 15.000 partos. Objetivo: Divulgar un caso clínico de interés para la comunidad médica por la asociación de la rotura uterina con un factor de riesgo poco establecido como es la presión fúndica (Maniobra de Kristell...

  2. Umbilical cable recovery load analysis

    Science.gov (United States)

    Yan, Shu-wang; Jia, Zhao-lin; Feng, Xiao-wei; Li, Shi-tao

    2013-06-01

    Umbilical cable is a kind of integrated subsea cable widely used in the exploration and exploitation of oil and gas field. The severe ocean environment makes great challenges to umbilical maintenance and repair work. Damaged umbilical is usually recovered for the regular operation of the offshore production system. Analysis on cables in essence is a two-point boundary problem. The tension load at the mudline must be known first, and then the recovery load and recovery angle on the vessel can be solved by use of catenary equation. The recovery analysis also involves umbilical-soil interaction and becomes more complicated. Calculation methods for recovery load of the exposed and buried umbilical are established and the relationship between the position of touch down point and the recovery load as well as the recovery angle and recovery load are analyzed. The analysis results provide a theoretical reference for offshore on-deck operation.

  3. Colgajo de perforante de arteria mamaria interna (IMAP en paciente con condronecrosis laríngea

    Directory of Open Access Journals (Sweden)

    A. Lorite-Álvaro

    2013-12-01

    Full Text Available La condronecrosis laríngea es una complicación rara y grave que aparece en pacientes sometidos a radioterapia. Presentamos el caso clínico de un paciente con condronecrosis laríngea severa tratada mediante desbridamiento y cobertura con colgajo de perforante de arteria mamaria interna (IMAP. El colgajo se basó en una perforante del segundo espacio intercostal, previa localización con doppler manual. La zona donante se cerró directamente. El colgajo fue viable en un 100%, permitió una adecuada cobertura del defecto y quedó bien adaptado al mismo. La zona donante cicatrizó sin incidencias. Consideramos que el colgajo de perforante de arteria mamaria interna pediculado permite una solución fiable y adecuada para pacientes con condronecrosis laríngea postradioterapia.

  4. Variante anatómica: origen de la arteria hepática derecha de la arteria mesentérica superior

    Directory of Open Access Journals (Sweden)

    David Rodríguez Palomo

    2011-03-01

    Full Text Available Este trabajo describe la presencia de la variante anatómica que presenta la arteria hepática derecha como rama de la arteria mesentérica superior en un caso incidental de disección en la Escuela de Medicina de la Universidad de Costa Rica, dicha variante se presenta desde un 6,4% hasta un 18% por lo que debe siempre tenerse en cuenta durante cualquier cirugía hepatobiliar y más aún si se trata de cirugía de trasplante hepático. Así mismo se revisa el tema y su importancia clínica.This paper describes the presence of anatomical variation has the right hepatic artery as a branch of the artery superior mesenteric artery a case incidental to the School of Medicine, University of Costa Rica, said variant is present from 6.4% to 18% and should be always be taken into account during any hepatobiliary surgery and more so if it is liver transplant surgery. It also reviews the issue and its clinical significance.

  5. Origen anómalo de la arteria coronaria izquierda originándose de la arteria pulmonar. Reporte de caso y revisión de literatura

    Directory of Open Access Journals (Sweden)

    José Jiménez Vega

    2007-01-01

    Full Text Available Se presenta el caso de un lactante de 2 meses de edad que consultó por tos y dificultad respiratoria; al ser admitido en el servicio de urgencias, el abordaje inicial fue de una infección respiratoria baja (bronquiolitis pero la evolución tórpida y la presencia de cardiomegalia hizo sospechar una cardiopatía, diagnosticándose origen anómalo de la arteria coronaria izquierda que nace de la arteria pulmonar, la cual fue tratada quirúrgicamente con resultado favorable.2 month old male who was brought to the emergency department with a history of non productive cold, was noticed with difficulty breathing. He was admitted with the possible diagnosis of bronquioloitis. The poor evolution of the patient, and the presence of cardiomegaly, made the physicians look for a cardiopathy, and a diagnosis of anomalous left coronary artery from the pulmonary artery was made. He was stabilized and then was taken to the operating room and had his anomalous coronary artery reimplanted to his aorta

  6. El origen anatómico de la arteria coronaria septal del hámster sirio es un carácter heredable

    OpenAIRE

    Soto Navarrete, María Teresa; Arqué Gibernau, José M; Durán Boyero, Ana Carmen; Fernández Domínguez, María Carmen; Fernández Corujo, Borja; Lorenzale García, Miguel; Sans-Coma, Valentín

    2016-01-01

    Introducción y objetivos: En los roedores, incluidos los empleados en el laboratorio, las arterias coronarias son intramiocárdicas. Normalmente se distinguen 3 arterias coronarias, la derecha, que irriga el corazón derecho, la izquierda, que irriga el corazón izquierdo, y la septal, que irriga el septo interventricular. En el hámster sirio, una especie empleada como modelo en estudios sobre anomalías congénitas de las arterias coronarias, la arteria septal se origina de la coronaria derecha o...

  7. Uso de nifedipina en el manejo de la hiperestimulación uterina producida por misoprostol.

    Directory of Open Access Journals (Sweden)

    Rodrigo Cifuentes

    2009-11-01

    Full Text Available La medicina basada en la evidencia ha demostrado mediante una serie de estudios, la eficacia clínica de algunos fármacos, como el caso del misoprostol análogo de la prostaglandina E1 utilizado en obstetricia para lograr maduración cervical en inducción de trabajo de parto con cérvix no favorable, con un efecto no deseado en la mayoría de los casos como lo es la hiperestimulación uterina. Se diseñó un estudio clínico prospectivo entre noviembre, 2002 y febrero, 2003 en la Clínica Rafael Uribe Uribe del Instituto de Seguro Social, Cali, donde se incluyeron 29 pacientes con criterio para inducción del trabajo de parto con índice de Bishop no favorable; se les administró 50 mcg de misoprostol por vía vaginal y desarrollaron polisistolia (>5 contracciones en 10 minutos. A estas 29 pacientes se les suministró 20 mg de nifedipina por vía oral en el momento en que apareció la polisistolia y se estableció mediante el registro por monitoría electrónica maternofetal durante 30 minutos la disminución en el número, la duración de las contracciones y la “actividad uterina”.

  8. Umbilical Cable Recovery Load Analysis

    Institute of Scientific and Technical Information of China (English)

    YAN Shu-wang; JIA Zhao-lin; FENG Xiao-wei; LI Shi-tao

    2013-01-01

    Umbilical cable is a kind of integrated subsea cable widely used in the exploration and exploitation of oil and gas field.The severe ocean environment makes great challenges to umbilical maintenance and repair work.Damaged umbilical is usually recovered for the regular operation of the offshore production system.Analysis on cables in essence is a two-point boundary problem.The tension load at the mudline must be known first,and then the recovery load and recovery angle on the vessel can be solved by use of catenary equation.The recovery analysis also involves umbilicalsoil interaction and becomes more complicated.Calculation methods for recovery load of the exposed and buried umbilical are established and the relationship between the position of touch down point and the recovery load as well as the recovery angle and recovery load are analyzed.The analysis results provide a theoretical reference for offshore on-deck operation.

  9. Umbilical cord blood transplantation.

    Science.gov (United States)

    Koo, Hong Hoe; Ahn, Hyo Seop

    2012-07-01

    Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients.

  10. Umbilical cord blood transplantation

    Directory of Open Access Journals (Sweden)

    Hong Hoe Koo

    2012-07-01

    Full Text Available Since the first umbilical cord blood transplantation (CBT in 1998, cord blood (CB has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients.

  11. Transfusão Intra-uterina na Isoimunização Materna pelo Fator Rh

    Directory of Open Access Journals (Sweden)

    Cabral Antonio Carlos Vieira

    2001-01-01

    Full Text Available Objetivos: avaliar os resultados do tratamento intra-útero de fetos anêmicos devido a isoimunização materna pelo fator Rh. Pacientes e Métodos: foram acompanhados 61 fetos submetidos a transfusão intra-uterina seja por via intraperitoneal, intravascular ou combinada. Os casos de fetos hidrópicos corresponderam a 19,7% do total, sendo que nestes a via de tratamento sempre foi a intravascular. Foram realizadas em média 2,7 transfusões por feto, com um total de 163 procedimentos. A indicação para a transfusão se baseou na espectrofotometria do líquido amniótico (método de Liley ou quando a dosagem de hemoglobina em sangue de cordão obtido por cordocentese fosse menor que 10 g/dl. Resultados: em metade dos casos submetidos a transfusão intra-uterina, empregou-se a via intravascular. Em relação aos casos de fetos hidrópicos a sobrevida foi de 46% e nos fetos não-hidrópicos, de 84%. Não ocorreram complicações maternas relacionadas ao procedimento. A idade média da interrupção da gestação foi de 34,8 semanas. Conclusões: apesar da melhora do resultado com a transfusão intra-uterina guiada pelo ultra-som e da cordocentese, a isoimunização materna pelo fator Rh permanece como causa de elevada morbimortalidade perinatal.

  12. Colgajo de perforante de arteria mamaria interna (IMAP) en paciente con condronecrosis laríngea

    OpenAIRE

    2013-01-01

    La condronecrosis laríngea es una complicación rara y grave que aparece en pacientes sometidos a radioterapia. Presentamos el caso clínico de un paciente con condronecrosis laríngea severa tratada mediante desbridamiento y cobertura con colgajo de perforante de arteria mamaria interna (IMAP). El colgajo se basó en una perforante del segundo espacio intercostal, previa localización con doppler manual. La zona donante se cerró directamente. El colgajo fue viable en un 100%, permitió una adecuad...

  13. SIGNIFICADO CLÍNICO DEL DOPPLER PATOLÓGICO EN LA ARTERIA CEREBRAL MEDIA EN FETOS DEL TERCER TRIMESTRE

    OpenAIRE

    2010-01-01

    Antecedentes: La flujometría Doppler fetal es usada de forma rutinaria y sistemática. Es incierta la utilidad clínica del Doppler de la arteria cerebral media (ACM) en fetos del tercer trimestre con crecimiento normal. Objetivo: Determinar los resultados perinatales en fetos del tercer trimestre con índice de pulsatilidad (IP) de la arteria cerebral media (ACM) bajo el percentil 5 comparado con fetos con Doppler cerebral normal. Método: Estudio de cohorte retrospectivo en fetos del tercer tri...

  14. Anatomía de la arteria temporal superficial: importancia quirúrgica: estudio piloto en cadáveres

    Directory of Open Access Journals (Sweden)

    J.J. Pradel-Mora

    2015-03-01

    Full Text Available El conocimiento preciso de los patrones vasculares permite mejorar los resultados de la reconstrucción regional del pabellón auricular y el diseño de colgajos regionales dependientes de la arteria temporal superficial para la reconstrucción facial. En México, no contamos en la actualidad con descripciones anatómicas de las variantes vasculares normales de la arteria temporal superficial. El objetivo de este trabajo es la descripción de las variantes anatómicas de la arteria temporal superficial a través de la disección de este vaso en 12 regiones tempo-parieto-occipitales en cadáveres. Nuestros resultados muestran que la arteria temporal superficial siempre se divide en dos ramas, una anterior y otra posterior, la distribución de ésta se sitúa en el cuarto más posterior de la región temporal, con una bifurcación alta. La distribución de la anatomía vascular, tomando en cuenta el calibre mayor de la arteria temporal superficial con respecto a la arteria auricular posterior, la ausencia de esta última en 4 de las regiones estudiadas, así como la distancia de dichos vasos con respecto al conducto auditivo externo, sugieren que en nuestra población la irrigación del pabellón auricular depende de la arteria temporal superficial, restándole importancia a la aportación del riego sanguíneo de esta región por parte de la arteria auricular posterior. Nuestro estudio arroja resultados que indican la existencia de variaciones importantes en la anatomía vascular regional que justifican la realización de estudios posteriores que permitan una descripción mas detallada de la misma para aumentar el éxito de las intervenciones quirúrgicas.

  15. Fontan pulsátil: Oclusión transcatéter de la arteria pulmonar permeable: Seguimiento a mediano plazo

    OpenAIRE

    Gamboa,Ricardo; Francisco P. Mollón; Ríos Méndez,Raúl E; Cayré,Raúl O; Cazzaniga,Mario; Arroyo,Graciela M; Gutiérrez,Diego F

    2008-01-01

    Objetivo: Reportamos la oclusión percutánea de la arteria pulmonar con flujo residual en pacientes con circuito tipo Fontan. Método: Niños de 9 y 11 años, SaO2 de 88 y 96% respectivamente, uno de ellos con cefalea y clase funcional II, ambos con anastomosis cavopulmonar total con tubo extracardíaco fenestrado y arteria pulmonar permeable (Fontan pulsátil). Un Amplatzer duct-occluder fue implantado en la arteria pulmonar ingresando desde la vena femoral. Control clínico, por imágenes y cateter...

  16. Influência do tipo de parto na hematologia do cordão umbilical de cães

    Directory of Open Access Journals (Sweden)

    Godoy Aline Vieira

    2005-01-01

    Full Text Available O sangue do cordão umbilical humano tem sido crescentemente utilizado como fonte de células-tronco. Os modelos experimentais de células-tronco da medula óssea, em cães, têm propiciado informações importantes para transplantes medulares em humanos. Vários trabalhos citam a influência do tipo de parto nas características do sangue do cordão umbilical (SCU humano. Entretanto, não existem relatos sobre a colheita do sangue do cordão umbilical de cães. O objetivo deste ensaio é avaliar a influência do tipo de parto na hematologia do cordão umbilical de cães. No presente protocolo experimental, foram estudados 54 fetos de cães, ao final da vida intra-uterina, provenientes de parto normal (n=24 e cesariana (n=30. A colheita de sangue do cordão umbilical foi realizada com seringa de cinco mL contendo solução anticoagulante EDTA (1mg/1mL sangue. Em seguida, a contagem global de hemácias, leucócitos, plaquetas, a determinação da concentração de hemoglobina, taxa de hematócrito, os índices eritrocitários foram realizados no contador automático de células. A contagem diferencial de leucócitos foi determinada em esfregaços de SCU corados com May-Grunwald-Giemsa (MGG. Com relação ao eritrograma e ao plaquetograma, não houve diferença significativa entre as amostras obtidas em cesarianas e partos normais. Os valores do leucograma do SCU colhido em partos normais foram superiores àqueles obtidos em cesarianas (P<0,05. Portanto, o tipo de parto influencia os valores hematológicos do cordão umbilical de cães.

  17. Pseudo-aneurisma post-traumático de tronco de arteria coronaria izquierda

    Directory of Open Access Journals (Sweden)

    Melina M. Gallo

    2011-08-01

    Full Text Available El pseudo-aneurisma de arteria coronaria es extremadamente raro. Su historia natural es poco conocida y su tratamiento discutido. Se presenta el caso de un paciente con pseudo-aneurisma de tronco de la coronaria izquierda e infarto antero-apical del ventrículo izquierdo cinco años después de un paro cardíaco secundario a un traumatismo no penetrante de tórax. Se consideró entonces que la lesión no era pasible de corrección percutánea o quirúrgica por lo que se optó por tratamiento médico conservador. Una angiografía coronaria por tomografía computarizada multicorte realizada 10 años después del evento inicial mostró ausencia de progresión de la lesión.

  18. Fibular free flap with arteria peronea magna: the role of preoperative balloon occlusion.

    Science.gov (United States)

    Rahmel, Benjamin B; Snow, Thomas M; Batstone, Martin D

    2011-03-01

    The free fibular osteocutaneous flap is a commonly used donor for reconstruction of mandibular defects. Vascular abnormalities and leg trauma are relative contraindications to the use of a fibular free flap. Peroneal arteria magna (PAM) is one such vascular abnormality that may preclude the use of the graft due to the high risk of lower-limb ischemia. Lower-limb angiography is the standard for assessing the lower-limb vascular anatomy; however, the indications remain controversial. Although balloon occlusion has been used to assess the vascular supply in distal bypass surgery, there have no reported cases of balloon occlusion to assess the viability of the distal extremity with PAM. Intraoperative assessment of vascular anatomy with an aborted harvest can lead to significant morbidity and cost. Balloon occlusion provides a relatively safe and minimally invasive technique for assessment of potential lower-limb ischemia in patients with PAM.

  19. Efecto de la endotelina-1 sobre las arterias tumorales de pacientes con neoplasia colorrectal Effect of endothelin-1 on tumor arteries in patients with colorectal cancer

    Directory of Open Access Journals (Sweden)

    E. Ferrero Herrero

    2008-06-01

    Full Text Available La endotelina-1 es un péptido vasoconstrictor producido por el endotelio vascular, cuyos niveles plasmáticos están aumentados en los pacientes con cáncer colorrectal y que puede participar en la regulación del flujo sanguíneo tumoral. Para estudiar si la respuesta a este péptido está alterada en las arterias tumorales, se obtuvieron, de 13 pacientes intervenidos quirúrgicamente por cáncer colorrectal, arterias mesentéricas irrigando el tumor y arterias mesentéricas de una región alejada del tumor, y asimismo se obtuvieron arterias mesentéricas de pacientes intervenidos por diverticulitis (n = 4 o enfermedad inflamatoria intestinal (n = 3. Las arterias mesentéricas se montaron en una preparación para el registro de la contracción isométrica en un baño de órganos, encontrándose que la endotelina-1 producía contracción en los tres tipos de arterias, pero la sensibilidad a este péptido fue mayor en las arterias irrigando el tumor que en las arterias alejadas del tumor o en las arterias de pacientes sin patología tumoral. Estos resultados indican que la endotelina-1 puede regular el flujo sanguíneo en los tumores colorrectales, produciendo una mayor vasoconstricción en las arterias que irrigan el tumor que en las arterias no tumorales.Endothelin-1 is an endothelium-derived vasoconstrictor peptide whose plasma levels are increased in patients with colorectal cancer, and which may be involved in tumor blood flow regulation. To study whether response to this peptide is altered in tumor arteries, mesenteric arteries supplying blood flow to colorectal tumors, and mesenteric arteries far from said tumors were obtained from 13 patients undergoing colectomy; mesenteric arteries were also obtained from patients with diverticulitis (n = 4 or inflammatory bowel disease (n = 3. Arteries were prepared for isometric tension recording in an organ bath, and in this preparation it was found that endothelin-1 induced contraction in all three

  20. Evaluación de diferentes tratamientos en el posparto temprano a vacas lecheras con infecciones uterinas

    OpenAIRE

    Zita Wonchee Solórzano; Renato Raúl Lozano Domínguez; Everardo González Padilla

    2002-01-01

    Se evaluó el uso de tratamientos hormonales (GnRH y PGF2 #945;) y antibióticos (oxitetraciclina) en vacas lecheras Holstein Friesian con infección uterina en el posparto temprano (16.2 ± 3.8 días). Tratamientos: 1) testigo positivo (infectadas, no tratadas; n=30); 2) hormona liberadora de gonadotropinas (GnRH; n=29); 3) Prostaglandina F2 #945; (Pg; n=25); 4) oxitetraciclina (Ab; n=38); 5) GnRH+Pg (n=25); 6) GnRH+Ab (n=33); 7) Ab+Pg (n=25); 8) GnRH+Ab+Pg (n=29) y 9) testigo negativo (no infect...

  1. UTERINE PROLAPSE IN QUEEN AND UTERINE PROLAPSO UTERINO EM GATA E RETROFLEXÃO UTERINA EM CADELA

    Directory of Open Access Journals (Sweden)

    Giuliano Queiroz Mostachio

    2008-10-01

    Full Text Available

    Obstetrical emergencies are problem in veterinary clinics and hospital. So, the aim of this report is to describe the clinical-surgical aspect of one of them, the uterine prolapse. Complete protrusion and retroflexion of uterus had been diagnosed in a queen and female dog, respectively. After the stabilization of the animals and reduction of the prolapses followed by ovary-hysterectomy, one of the animals came to death due to septicemia and hypovolemic shock. Rapid assessment and intensive treatments are required to sustain the life of the animal.

    KEY WORDS: Cat, dog, uterine prolapse, uterine retroflexion.

    Emergências obstétricas, como o prolapso uterino, constituem um problema em clínicas e hospitais veterinários. Neste relato descreve-se o aspecto clínico-cirúrgico do prolapso uterino. Diagnosticaram-se, em uma gata e em uma cadela, protrusão completa e retroflexão uterina, respectivamente. Após a estabilização dos animais e redução dos prolapsos seguidos de ovário-histerectomia, um dos animais veio a óbito, em decorrência de septicemia e choque hipovolêmico. Portanto, a rápida avaliação e tratamentos intensivos são requeridos para assegurar a vida do animal.

     

    PALAVRAS-CHAVES: Cão, gato, prolapso uterino, retroflexão uterina

  2. Full-term pregnancy in umbilical hernia

    OpenAIRE

    2011-01-01

    While umbilical hernias frequently occur during pregnancy, the few reported cases of uterine or fibroid incarceration in ventral hernias during pregnancy all involved incisional abdominal wall defects from prior laparotomies and Cesarean sections; none involved umbilical hernias. We discuss the case of a 42-year-old well-developed, well-nourished grand multiparous woman (G8P7) with a huge umbilical hernia containing a 38-week gravid uterus, as well as her management and the avoidance of known...

  3. Gravid Uterus in an Umbilical Hernia

    OpenAIRE

    2012-01-01

    Umbilical hernias large enough to contain a gravid uterus are rare. We report a case of a woman with prolapse of a gravid uterus through a previously repaired umbilical hernia. Our plans for elective surgery with caesarean section and hernia repair were foiled by poor compliance. The hernia was repaired during an emergency caesarean section. We provide details of her management and briefly review the literature on umbilical hernias and pregnancy. Surgical management offers an opportunity for ...

  4. Distinct Presentations of Hernia of Umbilical Cord

    Science.gov (United States)

    Mirza, Bilal; Ali, Waqas

    2016-01-01

    Hernia of umbilical cord is a well-known entity which presents with herniation of small bowel into the proximal part of umbilical cord. It has very good prognosis after surgical repair. Occasionally, it can have distinct presentations and varied malformations at the umbilicus which have bearing on the course of treatment and final outcome. Herein, we describe various presentations and malformations associated with hernia of umbilical cord. Embryological extrapolation is attempted for the malformations at umbilicus. PMID:27896161

  5. Bypass coronario en un paciente con oclusión de la arteria iliaca izquierda: Precauciones a tomar en cuenta.

    OpenAIRE

    2015-01-01

    Se presenta el caso de un paciente varón de 82 años con Insuficiencia Cardiaca Congestiva (Fracción de Eyección de 20%) y Edema Agudo de Pulmón secundarios a Infarto Agudo de Miocardio extenso que requería cirugía de Bypass Coronario. Además, presentaba Enfermedad Oclusiva Aortoiliaca crónica con  oclusión total de la Arteria Iliaca Izquierda dependiente de circulación colateral a través de la Arteria Mamaria Interna Izquierda. Se decidió realizar la cirugía de bypass coronario sin utilizar di...

  6. Aneurysmatic dissection of an aberrant right subclavian artery; Disseziierendes Aneurysma einer aberranten Arteria subclavia dextra: Diagnose mittels Ultrafast-CT

    Energy Technology Data Exchange (ETDEWEB)

    Reittner, P. [Universitaetsklinik fuer Radiologie, Graz (Austria). Abt. fuer Allgemeine Radiologie; Stacher, R. [Universitaetsklinik fuer Radiologie, Graz (Austria). Abt. fuer Allgemeine Radiologie

    1996-01-01

    Diagnosis with Ultrafast-CT: An aneurysm of an aberrant right subclavian artery is a very rare cause for dysphagia. We describe such a case in a 67-year-old patient, diagnosed with Ultrafast-CT and discuss it together in concert with the embryology and the radiological findings. (orig.) [Deutsch] Eine aberrierende Arteria subclavia dextra ist eine seltene Ursache fuer Dysphagie. Anhand eines 67jaehrigen Patienten werden Embryologie und radiologische Charakteristika, diagnostiziert mittels Ultrafast-CT, diskutiert. (orig.)

  7. Diagnóstico y tratamiento de los aneurismas saculares de la arteria cerebral anterior

    Directory of Open Access Journals (Sweden)

    Raúl F. Matera

    1956-12-01

    Full Text Available Hacemos un estudio anátomo-funcional de la arteria cerebral anterior recalcando la importancia que tiene la ligadura de esta arteria. Sintetizamos la patogenia de los aneurismas en cuatro hechos fundamentales: los aneurismas vestigiales originados en brotes vasculares no desarrollados o que no han involucionado normalmente; la falta de desarrollo de la túnica elástica en la zona de bifurcación de los grandes vasos; la arterioesclerosis; los procesos inflamatorios de la túnica media (sífilis y micosis. Hacemos un estudio clínico de los aneurismas del complejo cerebral-comunicante anterior, llamando la atención sobre aquellos en los que, a las hemorragias subaracnoidales, se asocian manifestaciones en el fondo de ojo, trastornos psíquicos y fenómenos motores. Llamamos la atención sobre las formas pseudo-tumorales quiasmáticas y los denominados aneurismas trombosantes que originan el síndrome progresivo fronto-cíngulo-calloso. Estudiamos la radiología simple de los aneurismas de esta región, llamando la atención sobre las calcificaciones cirsoideas suprasellares y los fenómenos de erosión de la silla turca. Llamamos la atención sobre la importancia de la arteriografía para confirmar el diagnóstico, estudiar la circulación colateral, el tamaño, la forma y el pedículo del aneurisma, elementos fundamentales para el plan operatório. En el tratamiento quirúrgico descartamos, por ineficaz, la ligadura de la carótida interna en el cuello. Es fundamental el abordaje intracraneano por vía subfrontal en los aneurismas de la porción précomunicante y comunicante con desarrollo hacia abajo, mientras que, la via sagital-frontal se utilizará en los aneurismas de desarrollo hacia arriba ya sea de la comunicante o de la porción distal de la arteria cerebral anterior o sus ramas. Insistimos sobre un hecho muy importante cual es la anestesia y, en especial, el uso de la hipotensión controlada, insistiendo de que la tensión se

  8. Umbilical Hernia Repair with Proceed Ventral Patch

    Directory of Open Access Journals (Sweden)

    Salati Sajad Ahmad

    2014-07-01

    Full Text Available Umbilical hernia is one the commonest surgical lesions and there is a variety of methods available for its repair. Proceed Ventral Patch is a recent and novel innovation in hernia management and we present a successful management of umbilical hernia in a 45 years old obese patient with this technique

  9. Strangulated umbilical hernia in a child.

    OpenAIRE

    1983-01-01

    We describe a case of strangulated umbilical hernia in a girl aged 5 years. She presented with an acute inflammatory lesion at the umbilicus which was initially thought to be due to cellulitis with possible abscess formation. Exploration revealed an umbilical hernia containing necrotic greater omentum.

  10. Therapy of umbilical hernia during laparoscopic cholecystectomy.

    Science.gov (United States)

    Zoricić, Ivan; Vukusić, Darko; Rasić, Zarko; Schwarz, Dragan; Sever, Marko

    2013-09-01

    The aim of this study is to show our experience with umbilical hernia herniorrhaphy and laparoscopic cholecystectomy, both in the same act. During last 10 years we operated 89 patients with cholecystitis and pre-existing umbilical hernia. In 61 of them we performed standard laparoscopic cholecystectomy and additional sutures of abdominal wall, and in 28 patients we performed in the same act laparoscopic cholecystectomy and herniorrhaphy of umbilical hernia. We observed incidence of postoperative herniation, and compared patients recovery after herniorrhaphy combined with laparoscopic cholecystectomy in the same act, and patients after standard laparoscopic cholecystectomy and additional sutures of abdominal wall. Patients, who had in the same time umbilical hernia herniorrhaphy and laparoscopic cholecystectomy, shown better postoperative recovery and lower incidence of postoperative umbilical hernias then patients with standard laparoscopic cholecystectomy and additional abdominal wall sutures.

  11. Carcinoma urotelial primario de la trompa uterina, una patología infrecuente: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Stefano Pozzobon-Borregales

    2013-01-01

    Full Text Available El carcinoma primario de la trompa uterina es una patología maligna infrecuente que ocurre entre el 0,1% al 1,8% de todos los tumores malignos del organismo, siendo aun menos frecuente el tipo histológico transicional o urotelial que representa el 10% de los tumores malignos de trompa uterina. Se presentan principalmente entre la 5ta y 7ma décadas de la vida, y clínicamente se manifiesta, en el 18% de los casos, con la triada de masa palpable y/o distensión abdominal, dolor pélvico y metrorragia. Presentamos el caso de una paciente de 44 años de edad quien inicia enfermedad actual en diciembre del 2010, con antecedente de dolor pélvico y sangrado genital continuo. En la resonancia magnética se apreció un lesión ocupante de espacio parauterina derecha, sugestiva de neoplasia maligna de ovario derecho. El reporte del marcador tumoral Ca 125 mostró valores elevados, acompañado de clínica y paraclínica sugestiva enfermedad tumoral maligna. Se decidió realizar laparotomía ginecológica en la que se evidenció tumoración en trompa uterina derecha. El estudio histológico se concluyó como carcinoma con diferenciación uroterial. Posteriormente se realizó cirugía de estadiaje, que incluyó lavado peritoneal, histerectomía total, salpingooforectomía izquierda, omentectomía subcolónica, apendicectomía y linfadenectomía bilateral selectiva. El reporte de biopsia de dichas piezas operatorias resultaron negativas para malignidad. La paciente se encuentra actualmente libre de enfermedad. Dado lo infrecuente de la patología se reporta este caso. Primary Carcinoma of the uterine tube, an unusual malignant pathology: case report Abstract Primary Carcinoma of the uterine tube is an unusual malignant pathology that occurs between the 0,1% and the 1,8% of all malignant tumors, being the urothelial histological type even less frequent, which represents 10% of malignant tumors of the uterine tubes. These tumors usually appear in women

  12. Prolapso de tuba uterina após histerectomia vaginal: relato de caso Fallopian tube prolapse after vaginal hysterectomy: a case report

    Directory of Open Access Journals (Sweden)

    Maurício B. Noviello

    2003-12-01

    Full Text Available O prolapso de tuba uterina é complicação rara após histerectomia, com aproximadamente 80 casos descritos na literatura. A sintomatologia é inespecífica, podendo incluir sangramento genital, dispareunia e dor pélvica crônica. O diagnóstico diferencial deve ser feito com granuloma de cúpula vaginal e carcinoma de vagina. O tratamento deve ser individualizado, podendo ser realizado por via vaginal, abdominal ou laparoscópica. Relatamos o caso de uma paciente, 47 anos, com miomatose uterina, submetida a histerectomia vaginal, evoluindo com prolapso de tuba uterina após 11 meses de pós-operatório. O exame especular evidenciava lesão vegetante, friável e sangrante localizada na cúpula vaginal. Esses achados clínicos sugeriam o diagnóstico de prolapso de tuba uterina. A paciente foi submetida a nova intervenção cirúrgica, com ressecção da tuba uterina por via vaginal. O exame natomopatológico confirmou o diagnóstico e a paciente evoluiu com remissão completa da sintomatologia.Fallopian tube prolapse is a rare complication after hysterectomy, with approximately 80 cases described in the literature. The symptoms are nonspecific including vaginal bleeding, dyspareunia and chronic pelvic pain. The differential diagnosis must be done with granulation tissue of the vaginal cuff and vaginal carcinoma. The treatment should be individualized, and is possible to be done by vaginal, abdominal or laparoscopic approach. We report a case of a 47-year-old woman with myoma who was submitted to a vaginal hysterectomy and evolved with fallopian tube prolapse 11 months after surgery. Specular examination showed a fungating, friable and bleeding lesion at the vaginal cuff. The clinical findings suggested the diagnosis of fallopian tube prolapse. The patient was submitted to a new surgical intervention with resection of the left fallopian tube. The histologic examination confirmed the diagnosis and the patient evolved with complete remission of

  13. Bancos de cordón umbilical Umbilical cord banks

    OpenAIRE

    2009-01-01

    La utilización de sangre de cordón como fuente de precursores hematológicos se remonta a 1983 cuando Boyse apuntó el potencial en progenitores existente en la sangre de cordón, realizándose un año más tarde las primeras experiencias sobre modelos murinos. Tuvieron que pasar más de cinco años para que Gluckman realizara la primera experiencia en humanos. Un niño afecto de anemia de Fanconi fue trasplantado con progenitores de sangre de cordón umbilical de su hermana HLA idéntica, realizándose ...

  14. The Roach muscle bundle and umbilical cord coiling

    NARCIS (Netherlands)

    de Laat, Monique W. M.; Nikkels, Peter G. J.; Franx, Arie; Visser, Gerard H. A.

    2007-01-01

    Objective: To determine if presence of the Roach muscle, a small muscle bundle tying just beside the umbilical artery, contributes to umbilical cord coiling. Methods: 251 umbilical cords were examined. The umbilical coiling index (UCI) was calculated as the number of coils divided by the cord length

  15. Concomitant sublay mesh repair of umbilical hernia and abdominoplasty

    OpenAIRE

    2012-01-01

    Concomitant mesh repair of large umbilical hernias and abdominoplasty pose a serious risk of devascularizing the umbilical stalk. A technique of placing mesh in a sublay manner, deep to the fascial defect, for an umbilical herniorrhaphy to avoid damage to the deep umbilical perforators during an abdominoplasty is described.

  16. Gravid Uterus in an Umbilical Hernia

    Directory of Open Access Journals (Sweden)

    Lawrence C. E. Mbuagbaw

    2012-01-01

    Full Text Available Umbilical hernias large enough to contain a gravid uterus are rare. We report a case of a woman with prolapse of a gravid uterus through a previously repaired umbilical hernia. Our plans for elective surgery with caesarean section and hernia repair were foiled by poor compliance. The hernia was repaired during an emergency caesarean section. We provide details of her management and briefly review the literature on umbilical hernias and pregnancy. Surgical management offers an opportunity for hernia repair and can ensure a safe delivery for the mother and child.

  17. Umbilical and epigastric hernia repair.

    Science.gov (United States)

    Muschaweck, Ulrike

    2003-10-01

    The repair of umbilical and epigastric hernias still represents a challenge to surgeons. Although a common and relatively simple procedure, there is no exact protocol today on how the repair should be done. The Mayo technique and its alterations could not stand the test of time: a recurrence rate of 20% and higher is not acceptable for any surgical procedure. Although there is no consensus opinion, one thing is clear: the importance of an anatomic repair without tension and without an artificial enlargement of the defect. In 1987 Lichtenstein reported on 6321 cases of herniorraphy with a tension free repair, and in 1994 Stuart reemphasized that special importance in his editorial in the Lancet. A newer study from Brancato and coworkers in Italy also states the advantage of a tension-free prosthetic repair in 16 patients with epigastric hernia. We have gone even further and recommend a tailored-to-the-patient repair using a customized polypropylene mesh and a one-layer running suture. The advantages should be obvious: no artificial creation of an even bigger than original defect, a completely tension-free repair, and little to no recurrence of the hernia. Our results clearly prove that assumption. Moreover, the procedure is extremely safe and complications are very rare and minor. We conclude that using a mesh plug in a customized tension-free repair of umbilical and epigastric hernia shows many advantages over the commonly used methods. And we finally conclude with the words of Albert Einstein: "The only source of knowledge is experience."

  18. Tratamiento de la compresión del tronco de la arteria coronaria izquierda en pacientes con hipertensión pulmonar

    Directory of Open Access Journals (Sweden)

    María L. Talavera

    2011-10-01

    Full Text Available La angina de pecho es un síntoma frecuente en pacientes con hipertensión pulmonar (HP de cualquier etiología. Aunque su fisiopatología no está aclarada, las causas propuestas son: la isquemia subendocárdica por aumento del estrés parietal del ventrículo derecho, la dilatación de la arteria pulmonar por incrementos transitorios de la presión pulmonar y la compresión extrínseca del tronco de la arteria coronaria izquierda (TCI por la arteria pulmonar (AP dilatada. Se presentan tres casos que muestran la relación entre la angina de pecho y la compresión del TCI en pacientes con HP asociada a cardiopatías congénitas, tratados mediante implante de stent coronario.

  19. Umbilical hernia repair in conjunction with abdominoplasty: a surgical technique to maintain umbilical blood supply.

    Science.gov (United States)

    Bruner, Terrence W; Salazar-Reyes, Hector; Friedman, Jeffrey D

    2009-01-01

    Abdominal wall hernias are often diagnosed on clinical examination or encountered intraoperatively during an abdominoplasty. Traditional surgical techniques for abdominoplasty and umbilical hernia repair, when performed simultaneously, can potentially compromise the vascular supply to the umbilicus. The authors describe a simplified surgical technique for the correction of umbilical hernias in conjunction with abdominoplasty. This procedure avoids any fascial incisions immediately adjacent to the umbilicus, thereby maintaining a maximal blood supply to the umbilical stalk. Over a six-year period, 17 patients underwent the described procedure. None have had a recurrence of their hernia or umbilical necrosis, and the aesthetics of the umbilicus have been improved.

  20. Endovascular Management of the Arteria Profunda Femoralis: Long-Term Angiographic and Clinical Outcomes

    Energy Technology Data Exchange (ETDEWEB)

    Karnabatidis, Dimitrios, E-mail: karnaby@med.upatras.gr; Spiliopoulos, Stavros; Pastromas, Georgios; Katsanos, Kostantinos; Siablis, Dimitrios [Patras University Hospital, School of Medicine, Department of Diagnostic and Interventional Radiology (Greece)

    2012-10-15

    Purpose: This study was designed to investigate the long-term angiographic and clinical outcomes of percutaneous transluminal angioplasty (PTA) of the arteria profunda femoralis (PFA), in a series of patients suffering from critical limb ischemia (CLI) or severe intermittent claudication (IC). Methods: Our department's database was searched to identify patients who underwent PTA or bail-out stenting of the PFA. Among the study's inclusion criteria were Rutherford categories 3-6 and {>=}70% stenosis of the PFA. Only de novo stenotic lesions were assessed. Primary endpoints were technical success, angiographic lesion primary patency, angiographic binary in-lesion restenosis, and target lesion recanalization (TLR) rates. Secondary endpoints included patient survival, limb salvage, and complication rates. Patient's baseline demographics, lesion, and procedural details were analyzed. Results: Between 2001 and 2011, 20 consecutive patients (17 males) with a mean age of 73 {+-} 9 (range 53-87) years underwent PTA or bail-out stenting in 23 PFA lesions. Critical limb ischemia was the indication in eight of 20 patients (40%). The mean lesion length was 31 {+-} 9.5 mm. The procedural technical success was 100% (23/23), whereas mean time angiographic and clinical follow-up was 26.8 {+-} 24.6 months. According to the Kaplan-Meier analysis, primary patency and binary restenosis rate were 95 and 86.1% respectively up to 8 years follow-up. No TLR procedures were performed. The 8-year patient survival and limb salvage rates were 87.5 and 84.7% respectively. Conclusions: PTA or stenting of focal, stenotic, PFA lesions, in patients suffering from CLI or IC, exhibit high long-term primary patency rates, as well as low binary restenosis and TLR rates. Large, multicenter studies are required to validate these results.

  1. Punciones repetidas de la arteria radial para cateterismo cardíaco Repeated radial artery puncture for cardiac catheterization

    Directory of Open Access Journals (Sweden)

    Eduardo Magariños

    2007-06-01

    Full Text Available La punción percutánea de la arteria radial para la realización de procedimientos por cateterismo ha ganado aceptación debido a una eficacia similar a la obtenida con el acceso femoral. En el presente trabajo evaluamos los resultados obtenidos con la punción repetida de esta arteria. En un total de 182 accesos radiales se realizaron 17 punciones repetidas, y mediante ellas, 20 procedimientos (9 coronariografías y 11 angioplastias. Se obtuvo éxito del acceso en 15 punciones repetidas (88.2% y éxito del procedimiento en todos los casos cuando logramos éxito del acceso. Si bien el grupo es pequeño es suficiente para mostrar que la punción repetida de la arteria radial es factible y permite una alta tasa de éxito de los procedimientos con una disminución ostensible de las complicaciones locales.The radial artery approach for percutaneous cardiac interventions has gained worldwide acceptance due to the similar results obtained by the femoral artery access. In this paper, we report our experience with repeated puncture of the radial artery. One hundred and eighty two radial artery access procedures were performed, in 17 interventions the puncture was repeated once or twice, with a total of 20 therapeutic catheterizations (9 coronary angiographies, 11 angioplasties. There was no therapeutic failure through the radial approach but, we successfully gained access in 88.2% (15/17 of the re-interventions cases. Although an experience with a low number of cases, we had a very high successful therapeutic rate, and also a remarkable lowering of local complications, this shows the feasibility and potential of this technique.

  2. Dissektion der Arteria carotis als Ursache ischämischer zerebrovaskulärer Ereignisse - Fallberichte und Diskussion

    Directory of Open Access Journals (Sweden)

    Tentschert S

    2003-01-01

    Full Text Available Dissektionen der kraniozervikalen Gefäße, inbesondere der Arteria carotis, zählen zu den häufigsten Ursachen ischämischer zerebrovaskulärer Ereignisse bei jüngeren Patienten. Die ischämische Symptomatik wird durch eine Wühlblutung in die Gefäßwand verursacht, welche entweder zu einer Minderung des zerebralen Blutflusses und/oder zu einer lokalen Thrombosierung mit nachfolgender Embolisation führt. Karotisdissektionen können durch ein mechanisches Trauma hervorgerufen werden, sie entstehen aber auch spontan oder sind dann bei einem Teil der Patienten mit Bindegewebserkrankungen assoziiert. Zu den häufigsten Symptomen zählen Kopfschmerzen, zervikaler Schmerz und Horner-Syndrom. Die zerebrale Ischämie führt meist zu einer transienten ischämischen Attacke (TIA oder zu einem ischämischen Infarkt im Stromgebiet der Arteria cerebri media der betroffenen Seite. Auch eine Amaurosis fugax kann auftreten. Trotz neuer technischer Möglichkeiten stellen Dissektionen der hirnversorgenden Gefäße nach wie vor eine diagnostische Herausforderung dar. Die digitale Subtraktionsangiographie gilt derzeit noch als Goldstandard zur Diagnostik, wird aber in vielen Fällen zunehmend durch neue nichtinvasive bildgebende Verfahren ersetzt oder ergänzt. Stenose oder Verschluß des betroffenen Gefäßes bilden sich in den meisten Fällen innerhalb von zwei Monaten nach dem Ereignis zurück. Therapeutische Maßnahmen haben vor allem die Verhinderung embolischer Komplikationen zum Ziel. Die gegenständliche Arbeit soll anhand von Fallbeispielen und einer Literaturübersicht klinisch relevante Aspekte und Probleme bei Diagnostik und Therapie der Dissektion der Arteria carotis aufzeigen.

  3. Endovascular treatment of splenic artery aneurysms; Trattamento endovascolare degli aneurismi dell'arteria splenica

    Energy Technology Data Exchange (ETDEWEB)

    Lagana, Domenico; Carrafiello, Gianpaolo; Mangini, Monica; Fontana, Federico; Dizonno, Massimiliano; Fugazzola, Carlo [Insubria Univ., Varese (Italy). Cattedra di radiologia; Castelli, Patrizio [Insubria Univ., Varese (Italy). Chirurgia vascolare

    2005-07-15

    techniques, endovascular treatment is feasible in nearly all SAAs. It ensures good immediate and long term results, and no doubt presents some advantages in comparison to surgical treatment, as it less invasive and allows the preservation of splenic function. [Italian] Scopo. Verificare l'efficacia del trattamento endovascolare degli aneurismi dell'arteria splenica (AAS). Materiale e metodi. Nel periodo compreso tra maggio 2000 e giugno 2003 sono stati trattati 11 AAS veri in 9 pazienti (7 femmine e 2 maschi; eta media 58 anni), 8 sacciformi e 3 fusiformi, 4 localizzati al tratto medio, 5 al tratto distale e 2 intrasplenici. La diagnosi e stata effettuata con eco color Doppler e/o angio-TC ed e risultata occasionate in 7 pazienti e conseguente a dolore in ipocondrio sinistro in 1 caso; un AAS e stato riscontrato in fase di fissurazione. Quattro AAS sono stati esclusi mediante embolizzazione della sacca con microspirali, con preservazione della continuita dell'asse vascolare; in 2 casi e stata associata l'iniezione transcatetere di cianoacrilato. In 4 casi e stata effettuata una legatura endovascolare, con ischemia settoriaie della milza. Un AAS fisstirato e stato trattato in urgenza con embolizzazione massiva mediante cianoacrilato dell'arteria splenica. I 2 aneurismi intrasplenici sono stati esclusi, l'uno mediante embolizzazione dell'arteria afferente con cianoacrilato e l'altro con iniezione transcatetere di trombina nella sacca aneurismatica. Risultati. E stata ottenuta la devascolarizzazione completa di tutti gli AAS (in 10/11 al termine della procedura; in 1/11 al controllo TC, effettuato dopo 3 giorni). Il follow-up (durata media 18 mesi; range 6-36 mesi) e stato espletato con eco color Doppler e/o angio-TC a 3, 6, 12 mesi e successivamente una volta all'anno; la completa esclusione degli aneurismi e stata confermata in 11/11 casi. Le complicanze riscontrate sono state: 4 casi di pleurite sinistra di modesta entita; febbre

  4. ISOINMUNIZACION Rh: EVALUACION DE LA UTILIDAD DEL DOPPLER DE ARTERIA CEREBRAL MEDIA EN LA PREDICCION Y MANEJO DE ANEMIA FETAL

    OpenAIRE

    2003-01-01

    Se presenta la experiencia en el manejo de pacientes altamente sensibilizadas por incompatibilidad Rh, analizando la utilidad de la evaluación de la velocidad circulatoria fetal, por Doppler-color, a través de la medición de la velocidad máxima sistólica (VMS) de la arteria cerebral media (ACM). Se realizan 19 transfusiones intravasculares en 3 casos afectados por esta enfermedad. En 14 de ellas se encontró anemia fetal moderada o leve, la que fue diagnosticada correctamente en 13 oportunidad...

  5. Origen anómalo de la arteria pulmonar derecha y estenosis de vena pulmonar superior izquierda

    OpenAIRE

    Patiño Bahena,Emilia; Calderón-Colmenero,Juan; Ramírez,Samuel; García Montes,José Antonio; Meave, Aloha; Erdmenger,Julio; Zabal,Carlos; Buendía,Alfonso

    2006-01-01

    Se presenta una niña de 9 meses con historia de cianosis desde el período neonatal, la valoración cardiológica integral que incluyó angiocardiografía y angiorresonancia magnética estableció los siguientes diagnósticos: Origen anómalo de la rama derecha de la arteria pulmonar naciendo de la aorta ascendente, estenosis de vena pulmonar superior derecha, persistencia del conducto arterioso e hipertensión arterial pulmonar a nivel sistémico. Se llevó a cirugía correctiva de todos los defectos de ...

  6. Tratamiento quirúrgico del síndrome de atrapamiento de arteria poplítea : nuestra experiencia

    OpenAIRE

    Merino Díaz, B.; Salvador Calvo, Roberto; Revilla Calavia, Álvaro; Carpintero Mediavilla, L.; González Fajardo, José Antonio; Vaquero Puerta, Carlos

    2013-01-01

    Producción Científica El síndrome de atrapamiento de la arteria poplítea (SAAP) es una entidad poco frecuente cuya incidencia varía del 0,17 al 3,5 %. Objetivo: Revisamos a los pacientes tratados quirúrgicamente en nuestro servicio durante los últimos 15 años. Material y métodos: Estudio retrospectivo entre 1995 y 2009, en que se registraron variables demográfi cas, comorbilidad, clínica, exploración física, pruebas complementarias, tratamiento quirúrgico realizado, así c...

  7. Parálisis del plexo braquial por pseudoaneurisma de la arteria axilar tras luxación de hombro

    OpenAIRE

    Escuder Capafons, M.C.; Monllau García, Juan Carlos; Ballester Soleda, Jorge

    1997-01-01

    Las lesiones del plexo braquial y de las arterias subclavia y axilar son complicaciones poco frecuentes, pero importantes, de los traumatismos dé la cintura escapular. Las lesiones neurovasculares son más frecuentes en heridas penetrantes, pero son raras en traumatismos cerrados. Cuando la sintomatología neurológica se desarrolla insidiosamente, días o semanas después del traumatismo, hay que pensar en una lesión vascular. Presentamos un caso de parálisis del plexo braquial tar...

  8. Anatomía del corazón y las arterias branquiales aferentes de las rayas (Chondrichthyes: Batoidea)

    OpenAIRE

    Abraham Kobelkowsky

    2012-01-01

    Se selecionó el corazón y el sistema branquial aferente de Dasyatis sabina como patrón morfológico de los Batoidea. Se compararon las cámaras del corazón y la ramificación de la aorta ventral en las arterias branquiales aferentes con las correspondientes de especies representativas de otras familias de batoideos, tales como: Narcine brasiliensis (Narcinidae), Rhinobatos lentiginosus (Rhinobatidae), Raja texana (Rajidae), Urobatis jamaicensis (Urolophidae), Gymnura micrura (Gymnuridae) y Mylio...

  9. Disección espontánea de arteria ilíaca asociada a ejercicio y uso de ergotamina

    OpenAIRE

    Fuenzalida G,Juan Pablo; Puentes R,Angel; Terrazas F,Sebastián; Osorio V,Sandra; Vergara C,Jorge; Schwartz Y,Eitan; Soumastre Ch,Rubén

    2012-01-01

    Introducción: La disección espontánea de la arteria ilíaca es un cuadro muy poco frecuente asociado a diferentes etiologías que habitualmente se presenta como isquemia de la extremidad comprometida. Caso clínico: Se reporta el caso de un paciente masculino de 48 años con antecedente de consumo crónico de ergotamina, quien mientras practicaba deporte presenta cuadro de isquemia aguda de la extremidad inferior izquierda. Angio tomografía computada demostró disección espontánea de la arteria ilí...

  10. Síndrome de atrapamiento de la arteria poplítea con aneurisma: reporte de un caso Popliteal entrapment syndrome caused by an aneurism: Case report

    OpenAIRE

    Tania Buccolini; Alberto Surur; Silvio Marchegiani; Luis Torrens; Claudia Bernal; Norberto Allende

    2010-01-01

    La verdadera prevalencia del síndrome de atrapamiento de la arteria poplítea es desconocida; se estima en un 0.16%. Se considera la principal causa de claudicación intermitente en jóvenes deportistas sin factores de riesgo cardiovasculares. Se caracteriza por la compresión extrínseca de la arteria poplítea, ya sea por defecto anatómico de las estructuras músculo-tendinosas o por hipertrofia de los músculos gemelos, lo cual ocasiona el atrapamiento y síntomas de parestesias, frialdad y claudic...

  11. Origen anómalo de la coronaria izquierda en la arteria pulmonar: resultados de la cirugía correctora

    OpenAIRE

    Andrés J. Schlichter; María I. Román; Christian Kreutzer; Ignacio Lugones

    2010-01-01

    IntroducciónEl origen anómalo de la arteria coronaria izquierda en la arteria pulmonar es una cardiopatía congénita rara que produce isquemia miocárdica con disfunción ventricular izquierda e insuficiencia mitral de grado variable. Las técnicas actuales han modificado la historia natural de esta enfermedad mediante el restablecimiento de un sistema de doble irrigación coronaria.ObjetivosEvaluar la experiencia institucional en la corrección quirúrgica del origen anómalo de la coronaria izquier...

  12. Umbilical Cord Segmental Hemorrhage and Fetal Distress

    Science.gov (United States)

    Larciprete, Giovanni; Romanini, Maria Elisabetta; Arduini, Domenico; Cirese, Elio; Slowikowska-Hilczer, Jolanta; Kula, Krzysztof

    2006-01-01

    We describe an unexplained case of umbilical cord segmental hemorrhage linked with meconium-stained amniotic fluid. A severely asphyxiated infant was delivered at term by Caesarean section. There were poor prognostic signs on fetal cardiotocography with rupture of membranes with meconium-stained amniotic fluid. The pathophysiologic mechanism in this case is still unknown, even if we argued a possible role of the umbilical cord shortness. PMID:23674981

  13. Umbilical Hernia Repair: Analysis After 934 Procedures.

    Science.gov (United States)

    Porrero, José L; Cano-Valderrama, Oscar; Marcos, Alberto; Bonachia, Oscar; Ramos, Beatriz; Alcaide, Benito; Villar, Sol; Sánchez-Cabezudo, Carlos; Quirós, Esther; Alonso, María T; Castillo, María J

    2015-09-01

    There is a lack of consensus about the surgical management of umbilical hernias. The aim of this study is to analyze the medium-term results of 934 umbilical hernia repairs. In this study, 934 patients with an umbilical hernia underwent surgery between 2004 and 2010, 599 (64.1%) of which were evaluated at least one year after the surgery. Complications, recurrence, and the reoperation rate were analyzed. Complications were observed in 5.7 per cent of the patients. With a mean follow-up time of 35.5 months, recurrence and reoperation rates were 3.8 per cent and 4.7 per cent, respectively. A higher percentage of female patients (60.9 % vs 29 %, P = 0.001) and a longer follow-up time (47.4 vs 35 months, P = 0.037) were observed in patients who developed a recurrence. No significant differences were observed between complications and the reoperation rate in patients who underwent Ventralex(®) preperitoneal mesh reinforcement and suture repair; however, a trend toward a higher recurrence rate was observed in patients with suture repair (6.5 % vs 3.2 %, P = 0.082). Suture repair had lower recurrence and reoperation rates in patients with umbilical hernias less than 1 cm. Suture repair is an appropriate procedure for small umbilical hernias; however, for larger umbilical hernias, mesh reinforcement should be considered.

  14. Evolution of umbilicals in Brazil: optimizing deepwater umbilical applications with thermoplastic hoses and steel tubes

    Energy Technology Data Exchange (ETDEWEB)

    Guerra Neto, Mauro Del [DuPont do Brasil S.A., Barueri, SP (Brazil)

    2008-07-01

    Subsea umbilicals in the past 25 years have evolved in parallel with other subsea oil and gas technologies, as the search for hydrocarbons needed to drive the global economy has led offshore exploration and development companies to seek reserves ever-farther from shore in water thousands of meters deep. Relegated to little more than afterthought status before the push into deep water, modern umbilicals have now become crucial components linking deep water producers to their subsea wells, controlling subsea production systems through hydraulic and electrical power and injecting production chemicals for corrosion-, scale-, and hydrate-inhibition at subsea well heads. Particularly in subsea developments involving several deep water wells, umbilicals today are integral to both the production-system design and the chosen operating strategy. Failure of an umbilical linking a subsea well head in deep water to a host production facility can inflict severe economic consequences upon an operator by impairing production operations or halting production altogether. The additional cost of repairing or replacing a failed umbilical can run into the millions of dollars. As offshore oil and gas production has moved into ever-deeper water, umbilical manufacturers have begun introducing new stronger materials to handle the inherently higher pressures and temperatures. Today, two types of construction are used for fluid conduits in umbilical systems deployed in deep water: thermoplastic hoses and steel tubes. Steel tubes are generally more expensive than thermoplastic hoses, relatively stiff and considered to have high tensile strength, while thermoplastic hoses are extremely flexible and exhibit lower tensile strength. This lower tensile strength of the hoses may be compensated by including steel wire armoring in the umbilical. This also provides the added benefits of additional mechanical protection compared with the equivalent unarmored steel-tubes umbilicals. When either

  15. Modelo computacional para caracterización de células escamosas de citologías cérvico-uterinas

    OpenAIRE

    Martínez Abaunza Víctor Eduardo; Mendoza Castellanos Alfonso; Uribe Pérez Claudia Janeth

    2007-01-01

    El trabajo se realizó entre el Grupo de Investigación en Ingeniería Biomédica (GIIB) y el Grupo de Investigación en Patología Estructural, Funcional y Clínica de la Universidad Industrial de Santander (UIS), junto con la Facultad de Medicina de la Universidad Autónoma de Bucaramanga (UNAB); el objetivo principal es construir un modelo computacional que permita caracterizar las células presentes en una citología cérvico uterina, con el propósito de clasificarlas como normales o displásicas. La...

  16. Colgajo de perforantes de la arteria colateral cubital inferior para defectos por quemadura eléctrica en fosa cubital

    Directory of Open Access Journals (Sweden)

    I. González-Alaña

    2014-09-01

    Full Text Available Las quemaduras eléctricas producen lesiones profundas, especialmente las debidas a la entrada y salida de la corriente y al arco voltaico, que pueden dejar expuestas estructuras nobles y afectar áreas de flexo-extensión, como la fosa antecubital. Los defectos resultantes pueden cubrirse mediante colgajos libres o pediculados de brazo y antebrazo. Entre las distintas opciones quirúrgicas, el colgajo medial del brazo evita la interrupción de los ejes vasculares mayores y la secuela en la zona donante es discreta. Sin embargo, su uso está poco extendido por considerarse un colgajo de difícil disección debido a la variabilidad anatómica de las arterias colaterales cubitales superior e inferior que lo irrigan. Presentamos la cobertura para un defecto secundario a quemadura eléctrica en la fosa antecubital mediante un colgajo medial del brazo basado en las ramas perforantes de la arteria colateral cubital inferior. Aunque confirmamos en este caso la variabilidad vascular, la disección resultó sencilla y el resultado estético y funcional fue excelente.

  17. Umbilical endometriosis associated with umbilical hernia. Management of a rare occurrence.

    Science.gov (United States)

    Iovino, Francesco; Ruggiero, Roberto; Irlandese, Eduardo; Gili, Simona; Lo Schiavo, Francesco

    2007-01-01

    We report a rare case of primitive umbilical endometriosis associated with umbilical hernia, which required wide umbilical resection and immediate reconstruction performed according to a recently described technique. A wide resection of the peritoneal sac was performed because of the possible presence of endometrial tissue inside. The hernia was repaired according to Mayo's technique. Umbilical reconstruction was performed using two semicircular skin flaps shaped into in an ellipse preoperatively drawn on the skin with a vertical orientation. The surgical approach described in this report allowed easy hernia repair and umbilical reconstruction. No prosthesis was used because of the small size of the hernia and lack of literature data on prosthesis use in endometriosis. The aesthetic result was considered satisfactory 6 months after the operation because of absence of hypertrophic scars and in view of the anatomical aspect of the new umbilicus. No recurrence was observed within this time frame.

  18. Evidence-based pathology: umbilical cord coiling.

    Science.gov (United States)

    Khong, T Y

    2010-12-01

    The generation of a pathology test result must be based on criteria that are proven to be acceptably reproducible and clinically relevant to be evidence-based. This review de-constructs the umbilical cord coiling index to illustrate how it can stray from being evidence-based. Publications related to umbilical cord coiling were retrieved and analysed with regard to how the umbilical coiling index was calculated, abnormal coiling was defined and reference ranges were constructed. Errors and other influences that can occur with the measurement of the length of the umbilical cord or of the number of coils can compromise the generation of the coiling index. Definitions of abnormal coiling are not consistent in the literature. Reference ranges defining hypocoiling or hypercoiling have not taken those potential errors or the possible effect of gestational age into account. Even the way numerical test results in anatomical pathology are generated, as illustrated by the umbilical coiling index, warrants a critical analysis into its evidence base to ensure that they are reproducible or free from errors.

  19. ACOG Committee Opinion No. 648: Umbilical Cord Blood Banking.

    Science.gov (United States)

    2015-12-01

    Once considered a waste product that was discarded with the placenta, umbilical cord blood is now known to contain potentially life-saving hematopoietic stem cells. When used in hematopoietic stem cell transplantation, umbilical cord blood offers several distinct advantages over bone marrow or peripheral stem cells. However, umbilical cord blood collection is not part of routine obstetric care and is not medically indicated. Umbilical cord blood collection should not compromise obstetric or neonatal care or alter routine practice for the timing of umbilical cord clamping. If a patient requests information on umbilical cord blood banking, balanced and accurate information regarding the advantages and disadvantages of public and private umbilical cord blood banking should be provided. The routine storage of umbilical cord blood as "biologic insurance" against future disease is not recommended.

  20. Committee Opinion No. 648 Summary: Umbilical Cord Blood Banking.

    Science.gov (United States)

    2015-12-01

    Once considered a waste product that was discarded with the placenta, umbilical cord blood is now known to contain potentially life-saving hematopoietic stem cells. When used in hematopoietic stem cell transplantation, umbilical cord blood offers several distinct advantages over bone marrow or peripheral stem cells. However, umbilical cord blood collection is not part of routine obstetric care and is not medically indicated. Umbilical cord blood collection should not compromise obstetric or neonatal care or alter routine practice for the timing of umbilical cord clamping. If a patient requests information on umbilical cord blood banking, balanced and accurate information regarding the advantages and disadvantages of public and private umbilical cord blood banking should be provided. The routine storage of umbilical cord blood as "biologic insurance" against future disease is not recommended.

  1. Prevalência de alterações uterinas e tubárias na histerossalpingografia em mulheres inférteis: estudo de 48 casos

    Directory of Open Access Journals (Sweden)

    Pérez Juliano Adams

    2001-01-01

    Full Text Available A histerossalpingografia é um exame realizado para avaliação da anatomia uterina e da permeabilidade tubária, característica esta que torna a pesquisa de causa de infertilidade primária ou secundária sua principal indicação. Este trabalho se propôs a estudar a prevalência de alterações na histerossalpingografia em pacientes com infertilidade. Para tal, foram alocadas todas as pacientes que se submeteram ao exame, num período de quatro meses. Entre as 48 pacientes estudadas, 36 apresentavam infertilidade primária e 12, infertilidade secundária. As pacientes com infertilidade primária apresentaram maior índice de malformações uterinas, enquanto as pacientes com infertilidade secundária apresentaram obstrução tubária como alteração mais freqüente. Não ocorreu nenhuma intercorrência significativa durante a realização dos exames. O trabalho permite afirmar que este exame é muito útil na pesquisa de infertilidade, uma vez que, freqüentemente, diagnostica alterações importantes, sendo um exame barato e de raras complicações.

  2. A Semicircular Incision in the Superior Umbilical Fold for SILS Preserves the Umbilical Profile

    Directory of Open Access Journals (Sweden)

    S. C. Blackburn

    2012-01-01

    Full Text Available Background. Single Incision Laparoscopic Surgery (SILS has been highlighted in the recent literature as a means of performing a range of common, minimal access, paediatric surgical procedures. The primary attraction is the absence of visible scarring. Aim. This study aims to describe a cosmetically advantageous means of SILS port placement in children, which preserves the umbilical profile. Methods. We describe a paediatric case series utilising a semicircular incision in the superior umbilical fold for SILS procedures. The linea alba is exposed over 2 cm just superior to the umbilical ring and stay sutures are applied. A vertical incision is made over this distance without entering the umbilical ring. Data were recorded prospectively in a Microsoft Excel database. Results. Twenty-one cases were performed in a 1-year period. Ten appendicectomies, 5 ovarian/paraovarian cystectomies, 2 Palomo procedures, 3 nephrectomy/heminephrectomies, and 1 Meckel’s diverticulectomy were performed. There was 1 wound infection. No incisional hernias occurred. Discussion. We believe that our technique, which maintains the integrity of the umbilical ring and allows preservation of the umbilical profile, offers a distinct cosmetic advantage over other incisions for SILS which distort it. Conclusion. We have demonstrated the aesthetic benefits of utilising a superior umbilical-fold incision for SILS in children.

  3. Full-term pregnancy in umbilical hernia

    Directory of Open Access Journals (Sweden)

    Damien Punguyire

    2011-01-01

    Full Text Available While umbilical hernias frequently occur during pregnancy, the few reported cases of uterine or fibroid incarceration in ventral hernias during pregnancy all involved incisional abdominal wall defects from prior laparotomies and Cesarean sections; none involved umbilical hernias. We discuss the case of a 42-year-old well-developed, well-nourished grand multiparous woman (G8P7 with a huge umbilical hernia containing a 38-week gravid uterus, as well as her management and the avoidance of known complications that have occurred in similar incisional hernia cases. Successful pregnancy outcomes can occur in cases of pregnancies in ventral hernias, even in resource-poor settings that have Cesarean section capabilities

  4. Temporary umbilical loop colostomy for anorectal malformations.

    Science.gov (United States)

    Hamada, Yoshinori; Takada, Kohei; Nakamura, Yusuke; Sato, Masahito; Kwon, A-Hon

    2012-11-01

    Transumbilical surgical procedures have been reported to be a feasible, safe, and cosmetically excellent procedure for various pediatric surgical diseases. Umbilical loop colostomies have previously been created in patients with Hirschsprung's disease, but not in patients with anorectal malformations (ARMs). We assessed the feasibility and cosmetic results of temporal umbilical loop colostomy (TULC) in patients with ARMs. A circumferential skin incision was made at the base of the umbilical cord under general anesthesia. The skin, subcutaneous tissue, and fascia were cored out vertically, and the umbilical vessels and urachal remnant were individually ligated apart from the opening in the fascia. A loop colostomy was created in double-barreled fashion with a high chimney more than 2 cm above the level of the skin. The final size of the opening in the skin and fascia was modified according to the size of the bowel. The bowel wall was fixed separately to the peritoneum and fascia with interrupted 5-0 absorbable sutures. The bowel was opened longitudinally and everted without suturing to the skin. The loop was divided 7 days postoperatively, and diversion of the oral bowel was completed. The colostomy was closed 2-3 months after posterior saggital anorectoplasty through a peristomal skin incision followed by end-to-end anastomosis. Final wound closure was performed in a semi-opened fashion to create a deep umbilicus. TULCs were successfully created in seven infants with rectourethral bulbar fistula or rectovestibular fistula. Postoperative complications included mucosal prolapse in one case. No wound infection or spontaneous umbilical ring narrowing was observed. Skin problems were minimal, and stoma care could easily be performed by attaching stoma bag. Healing of umbilical wounds after TULC closure was excellent. The umbilicus may be an alternative stoma site for temporary loop colostomy in infants with intermediate-type anorectal malformations, who undergo radical

  5. Repair of umbilical and epigastric hernias.

    Science.gov (United States)

    Earle, David B; McLellan, Jennifer A

    2013-10-01

    Umbilical and epigastric hernias are primary midline defects that are present in up to 50% of the population. In the United States, only about 1% of the population carries this specific diagnosis, and only about 11% of these are repaired. Repair is aimed at symptoms relief or prevention, and the patient's goals and expectations should be explicitly identified and aligned with the health care team. This article details some relevant and interesting anatomic issues, reviews existing data, and highlights some common and important surgical techniques. Emphasis is placed on a patient-centered approach to the repair of umbilical and epigastric hernias.

  6. Porous nematic microfluidics for generation of umbilic defects and umbilic defect lattices

    Science.gov (United States)

    Aplinc, Jure; Morris, Stephen; Ravnik, Miha

    2016-06-01

    We demonstrate that porous nematic microfluidics is a potential route for the generation of nematic umbilic defects and regular umbilic defect lattices. By using numerical modeling we show that the mutual (backflow) coupling between the flow velocity and the orientation director field of the nematic liquid crystal leads to the formation of positive umbilic defects at local peaks and to the formation of negative umbilic defects at the local saddles in the flow profile. The number of flow peaks and the index of the flow saddles (i.e., the number of the valleys) are shown to be directly related to the strength of the umbilic defect, effectively relating the two fields at the geometrical level. The regular arrangement of the barriers in the porous channels is demonstrated to lead to the formation of regular lattices of umbilic defects, including square, triangular, and even kagome lattices. Experimental realization of such systems is discussed, with particular focus on microfluidic-tunable birefringent photonic band structures and lattices.

  7. The umbilical and paraumbilical veins of man.

    Science.gov (United States)

    Martin, B F; Tudor, R G

    1980-03-01

    During its transit through the umbilicus structural changes occur in the thick wall of the extra-abdominal segment of the umbilical vein whereby the components of the intra-abdominal segment acquire an essentially longitudinal direction and become arranged in fibro-elastic and fibro-muscular zones. The vein lumen becomes largely obliterated by asymmetrical proliferation of loose subendothelial conective tissue. The latter forms a new inner zone within which a small segment of the lumen persists in an eccentric position. This residual lumen transmits blood to the portal system from paraumbilical and systemic sources, and is retained in the upper part of the vein, even in old age. A similar process of lumen closure is observed in the ductus venosus. In early childhood the lower third of the vein undergoes breakdown, with fatty infiltration, resulting in its complete division into vascular fibro-elastic strands, and in old age some breakdown occurs in the outermost part of the wall of the upper two thirds. The paraumbilical veins are thick-walled and of similar structure to the umbilical vein. Together they constitute an accessory portal system which is confined between the layers of the falciform ligament and is in communication with the veins of the ventral abdominal wall. The constituents form an ascending series, namely, Burow's veins, the umbilical vein, and Sappey's inferior and superior veins. The main channel of Sappey's inferior veins may be the remnant of the right umbilical vein since it communicates with the right rectus sheath and often communicates directly with the portal system within the right lobe of the liver. The results are of significance in relation to clinical usage of the umbilical vein.

  8. Ciclo estral, histologia e ultra-estrutura do epitelio da tuba uterina da linhagem de ratos UChA e UChB (bebedores voluntarios de etanol)

    OpenAIRE

    Camila Contin Diniz de Almeida-Francia

    2005-01-01

    Resumo: O alcoolismo é o terceiro problema mais sério de Saúde Pública Mundial. A maioria é constituída de homens, entretanto, o índice de mulheres viciadas em bebidas alcoólicas vem aumentando. A tuba uterina promove o meio necessário para a maturação dos gametas femininos e masculinos (capacitação), a fertilização e o desenvolvimento inicial do embrião. As variedades UChA e UChB constituem modelos para os trabalhos relacionados aos aspectos genéticos, bioquímicos, fisiológicos, nutricionais...

  9. Symphysis-fundal height curve in the diagnosis of fetal growth deviations Curva de altura uterina por edad de gestación y diagnóstico de desvíos del crecimiento fetal Curva de altura uterina por idade gestacional e diagnóstico de desvios do crescimento fetal

    Directory of Open Access Journals (Sweden)

    Djacyr Magna Cabral Freire

    2010-12-01

    Full Text Available OBJECTIVE: To validate a new symphysis-fundal curve for screening fetal growth deviations and to compare its performance with the standard curve adopted by the Brazilian Ministry of Health. METHODS: Observational study including a total of 753 low-risk pregnant women with gestational age above 27 weeks between March to October 2006 in the city of João Pessoa, Northeastern Brazil. Symphisys-fundal was measured using a standard technique recommended by the Brazilian Ministry of Health. Estimated fetal weight assessed through ultrasound using the Brazilian fetal weight chart for gestational age was the gold standard. A subsample of 122 women with neonatal weight measurements was taken up to seven days after estimated fetal weight measurements and symphisys-fundal classification was compared with Lubchenco growth reference curve as gold standard. Sensitivity, specificity, positive and negative predictive values were calculated. The McNemar χ2 test was used for comparing sensitivity of both symphisys-fundal curves studied. RESULTS: The sensitivity of the new curve for detecting small for gestational age fetuses was 51.6% while that of the Brazilian Ministry of Health reference curve was significantly lower (12.5%. In the subsample using neonatal weight as gold standard, the sensitivity of the new reference curve was 85.7% while that of the Brazilian Ministry of Health was 42.9% for detecting small for gestational age. CONCLUSIONS: The diagnostic performance of the new curve for detecting small for gestational age fetuses was significantly higher than that of the Brazilian Ministry of Health reference curve.OBJETIVO: Validar la curva de referencia de altura uterina por edad de gestación para el rastreo de desvíos del crecimiento fetal y comparar su performance con la curva estándar adoptada por el Ministerio de la Salud de Brasil. MÉTODOS: Estudio observacional que envolvió 753 gestantes de bajo riesgo de Joao Pessoa, Noreste de Brasil, entre

  10. The umbilical and paraumbilical veins of man.

    OpenAIRE

    Martin, B F; Tudor, R G

    1980-01-01

    During its transit through the umbilicus structural changes occur in the thick wall of the extra-abdominal segment of the umbilical vein whereby the components of the intra-abdominal segment acquire an essentially longitudinal direction and become arranged in fibro-elastic and fibro-muscular zones. The vein lumen becomes largely obliterated by asymmetrical proliferation of loose subendothelial conective tissue. The latter forms a new inner zone within which a small segment of the lumen persis...

  11. Percutaneous ultrasound guided umbilical cord blood sampling

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Hyup; Choi, B. I.; Kim, C. W.; Youn, B. H.; Shin, H. C.; Kim, S. O. [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1989-12-15

    This report describes a technique and the result of percutaneous ultrasound-guided umbilical cord blood sampling and its potential use in the management of diagnostic problems in the second and third trimester of pregnancy. This method has been employed in the prenatal assessment of 19 fetuses at risk for chromosomal disorders, fetal hypoxia and hematologic disorders. This simple and rapid procedure offers a safe access to the fetal circulation

  12. The recurrent true umbilical cord knots: a case report

    Directory of Open Access Journals (Sweden)

    I Naghi

    2012-11-01

    Full Text Available Background: True umbilical cord knot is one of the abnormalities of the umbilical cord. Active fetal movements create cord knotting. True umbilical cord knots are rare but may be associated with fetal distress and stillbirth. True umbilical cord knots are capable of impeding blood flow to the fetus.Case presentation: A 26-year old primigravid woman was first treated for genital herpes simplex virus (HSV type 2 at 36 weeks of gestational age. She received oral acyclovir (400 mg three times daily for 10 days. At the gestational age of 38 weeks and 5 days, fetal activity decreased and NST was nonreactive. She was delivered by cesarean section and a true umbilical cord knot was found. Four years later, in her second pregnancy, another true knot was seen.Conclusion: Excessively long umbilical cords are more likely to be associated with true knots. Genetics has an important role in determining cord length and occurrence of true knots.

  13. Pseudo-umbilical Biharmonic Submanifolds in Constant Curvature Spaces

    Institute of Scientific and Technical Information of China (English)

    DU Li; ZHANG Juan

    2012-01-01

    The conjecture [1] asserts that any biharmonic submanifold in sphere has constant mean curvature.In this paper,we first prove that this conjecture is true for pseudo-umbilical biharmonic submanifolds Mn in constant curvature spaces Sn+P(c)(c > 0),generalizing the result in [1].Secondly,some sufficient conditions for pseudo-umbilical proper biharmonic submanifolds Mn to be totally umbilical ones are obtained.

  14. Umbilical paracentesis for acute hernia reduction in cirrhotic patients.

    Science.gov (United States)

    Russell, Katie W; Mone, Mary C; Scaife, Courtney L

    2013-10-16

    Emergent repair of umbilical hernias in cirrhotic patients is associated with a high risk for morbidity and mortality. We propose a new technique, umbilical paracentesis, for reduction of incarcerated hernias in the patient with ascites. Under ultrasound guidance, removal of ascitic fluid from the umbilical hernia sac can reduce the local pressure and thereby allow for easy hernia reduction, thus avoiding the need for an emergent operation.

  15. An ovary as unusual contents of an incarcerated umbilical hernia.

    Science.gov (United States)

    Ahmed, U; Ahmed, R; Kamat, S; Elkholy, K

    2014-09-01

    We present the unusual case of a woman presenting with an incarcerated umbilical hernia. Intraoperatively, the contents of the hernia were found to be an ovary. We outline the clinical presentation of our patient, investigations and management as well as a discussion on unusual contents of umbilical hernias. To our knowledge, this is the first case of a non-malignant ovary incarcerated in an umbilical hernia.

  16. [CLINICO-EXPERIMENTAL SUBSTANTIATION OF INTRAABDOMINAL PLASTY FOR UMBILICAL HERNIAS].

    Science.gov (United States)

    Joffe, O Yu; Shvets, I M; Tarasyuk, T V; Stetsenko, O P; Tsyura, Yu P

    2015-04-01

    The impact of various methods of plasty, using net implants, on results of umbilical hernias treatment was studied in experimental and clinical investigation. The umbilical hernias plasty was performed in accordance to the IPOM (intraperitoneal on lay mesh) method, application of which have permitted to reduce a hospital stay of the patients as well as their period of social rehabilitation, and to guarantee the best cosmetic effect in comparison with such while making umbilical hernias plasty in accordance to a sub lay method.

  17. Umbilical paracentesis for acute hernia reduction in cirrhotic patients

    OpenAIRE

    2013-01-01

    Emergent repair of umbilical hernias in cirrhotic patients is associated with a high risk for morbidity and mortality. We propose a new technique, umbilical paracentesis, for reduction of incarcerated hernias in the patient with ascites. Under ultrasound guidance, removal of ascitic fluid from the umbilical hernia sac can reduce the local pressure and thereby allow for easy hernia reduction, thus avoiding the need for an emergent operation.

  18. Umbilical cord blood transplantation: A review of atricles

    OpenAIRE

    1999-01-01

    Interest in umbilical cord blood as an alternative source of hematopietic stem cells is growing rapidly. Umbilical cord blood offers the clinician a source of hematopoietic stem cells that are readily available and rarely contaminated by latent viruses. Moreover, the collection of umbilical cord blood poses no risk to the donor. There is no need for general anesthesia or blood replacement and the procedure causes no discomfort. Current clinical experience suggests that the incidence of GVHD i...

  19. Postpartum deaths: piglet, placental, and umbilical characteristics.

    Science.gov (United States)

    Rootwelt, V; Reksen, O; Farstad, W; Framstad, T

    2013-06-01

    The fetal growth of the piglet is highly dependent on its placenta, and the newborn piglet birth weight is highly associated with postpartum death. However, there is little information available in the literature on the assessment of the placenta in relation to postpartum death in piglets. The aim of this study was to evaluate the impact of the placental area and placental weight, status of the umbilical cord, and piglet birth characteristics, such as blood parameters, vitality score, and birth weight on postpartum death. All live born piglets in litters from 26 Landrace-Yorkshire sows were monitored during farrowing and the status of each was recorded, including placental area and placental weight and blood variables obtained from the piglets and umbilical veins. Out of the 386 live-born piglets, 16.8% died before weaning at 5 wk. Among these, 78.5% died within the first 3 d of life. Mean blood concentration of lactate was increased in piglets that did not survive to weaning (P = 0.003). Concentrations of hemoglobin and hematocrit were decreased (P Piglets born with a broken umbilical cord had a reduced vitality score vs. piglets born with an intact umbilical cord (P = 0.021), and they had an increased probability of dying before weaning (P = 0.050). Mean birth weight, body mass index, placental area (P piglets that died before weaning vs. those that survived. Birth weight and placental area were furthermore negatively associated with live litter size. Blood concentrations of IgG and albumin recorded at d 1 were decreased in piglets that died before weaning (P < 0.01), and blood concentration of albumin was positively associated with placental area (P < 0.001). We conclude that placental area and placental weight, status of the umbilical cord, birth weight, body mass index, blood concentrations of lactate, hemoglobin, and hematocrit recorded at birth, and blood concentrations of IgG and albumin recorded at d 1 were associated with postpartum death in this study

  20. VARIACIONES DE LA ARTERIA DEL NODO SINOATRIAL EN POBLACIÓN COLOMBIANA Sino-atrial node artery variation in a sample of the Colombian population

    Directory of Open Access Journals (Sweden)

    Yobany Quijano-Blanco

    2012-03-01

    Full Text Available Antecedentes. El conocimiento exacto de la integración anatomofisiológica del sistema de conducción del corazón, es fundamental para la comprender la fisiopatología, el diagnóstico y el manejo de muchas de las complicaciones de la enfermedad coronaria y de las cardiopatías en general. Uno de los aspectos fundamentales, más variable y con mayores repercusiones clínicas corresponde al origen y recorrido de las arterias encargadas de irrigar el nódulo sinoatrial. Objetivo. Determinar el origen, recorrido y distribución de las arterias que irrigan el nódulo sinoatrial en una muestra de población colombiana. Material y métodos. La muestra de análisis fueron 60 bloques cardiopulmonares y digestivos seleccionados a través de muestreo por conveniencia. A estos se les realizó una disección convencional de los genitales para la determinación del sexo y posteriormente se procedió con la disección de las arterias coronarias específicamente de la arteria del nódulo sinoatrial, con el fin de establecer su origen y recorrido. Resultados. Como hallazgo principal se encontró que el origen de la arteria del nódulo sinoatrial en 75% provenía de la coronaria derecha, un 15% procedía de la arteria circunfleja y el 10% restante fue codominante. En cuanto al trayecto 86,6% fueron lineales, mientras 13,4% tuvieron formas alternas como Y, doble Y o en tridente. Conclusiones. Se evidenció predominio del origen de la arteria del nódulo sinoatrial en la coronaria derecha, hallazgo coincidente con investigaciones similares e independiente de la procedencia geográfica y el origen racial. Sin embargo, en este estudio se evidenciaron recorridos no reportados en la literatura como la distribución en Y, en doble Y, en K invertida y en tridente.Background. Accurate knowledge regarding the cardiac conduction system's anatomical-physiological integration is essential for understanding the pathophysiology, diagnosis and management of many complications

  1. Stentimplantation zur Behandlung von langstreckigen Verschlüssen der Arteria femoralis superficialis beidseites - Fallbericht eines Patienten mit Claudicatio intermittens

    Directory of Open Access Journals (Sweden)

    Schillinger M

    2004-01-01

    Full Text Available Die Einführung von selbstexpandierbaren Nitinol-Stents hat das Spektrum der endovaskulären Behandlungsmöglichkeiten im femoropoplitealen Stromgebiet deutlich erweitert. Die Ergebnisse der alleinigen Ballonangioplastie bei langstreckigen, ausgeprägt verkalkten Arteria femoralis superficialis (AFS-Verschlüssen sind erfahrungsgemäß schlecht, sodaß bei Claudicatio-Symptomatik meist entweder eine konservativ-medikamentöse Behandlung oder eine Bypass-Operation favorisiert werden. Mit der Applikation von Stainless-steel-Stents konnten zwar die initialen Resultate verbessert werden, aufgrund von häufig massiver neointimaler Proliferation waren jedoch die Langzeitergebnisse weiterhin nicht zufriedenstellend. Die Offenheitsraten von Nitinol-Stents im femoropoplitealen Bereich scheinen jedoch vielversprechend, sodaß diese Stents auch bei langstreckigen AFS-Verschlüssen bei Patienten mit Claudicatio intermittens zum Einsatz kommen könnten. Wir berichten hier über einen Patienten mit klinischen Beschwerden der Claudicatio intermittens im Stadium Fontaine IIb (Gehstrecke unter 200 m mit beidseits langstreckigen, ausgeprägt verkalkten AFS-Verschlüssen, die erfolgreich mit langstreckiger Stentimplantation therapiert werden konnten.

  2. Resolución microquirúrgica de aneurisma de arteria cubital en paciente pediátrico

    Directory of Open Access Journals (Sweden)

    A. Aguilera-Salgado

    2015-09-01

    Full Text Available Presentamos el caso clínico de un paciente varón de 6 años de edad con antecedente de caída desde su propia altura un mes antes de su valoración en consulta, en donde se identifica una tumoración pulsátil en región hipotenar de mano derecha, no dolorosa y no fija a planos profundos. El ultrasonido doppler informa de una tumoración con pared definida, heterogénea, con flujo sanguíneo a través de la misma. En base a los antecedentes y a los resultados del ultrasonido se decide intervenir quirúrgicamente para evitar posibles complicaciones, encontrando un aneurisma de la arteria cubital de 3 x 3 cm de diámetro, no trombosado, que resecamos, practicando reconstrucción mediante injerto venoso término-terminal. El paciente evolucionó sin complicaciones.

  3. Umbilical metastasis of unknown primary presenting as umbilical hernia: a case report

    Directory of Open Access Journals (Sweden)

    Ibrahim W Adamu

    2010-11-01

    Full Text Available Ibrahim W Adamu1, Noubar Kevorkian1, Genato Romulo1, Stephen S Carryl1, Armand Asarian1, Philip Q Xiao21Department of Surgery, 2Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USAAbstract: Umbilical metastasis is well known to be a late stage of malignancy and is associated with a poor prognosis. The majority of such cases are associated with primary gastrointestinal and gynecologic malignancies, and fewer cases are noted to derive from the thoracic cavity and the urinary tract. In this report, we describe a rare case of metastasis that presented as incarcerated umbilical hernia with no primary sites found. Extensive work-up, including tumor markers, imaging studies, endoscopies, and immunohistochemical analysis, failed to identify the primary source of this malignancy; this was a rare case of Sister Mary Joseph’s nodule with unknown primary. Therefore, it is very important for a surgeon to consider metastasis among the differential diagnosis of umbilical hernia.Keywords: umbilical metastasis, Sister Mary Joseph’s Nodule, hernia

  4. Umbilical varix presenting as an incarcerated umbilical hernia--a costly mistake if not recognised.

    OpenAIRE

    2004-01-01

    Incarcerated umbilical hernias commonly present as emergencies. Often they are diagnosed clinically and repaired surgically. In the case reported here, surgery could have been complicated by a major haemorrhage. An accurate history, high index of suspicion and attention to detail are paramount.

  5. Umbilicoplasty in children with huge umbilical hernia

    Directory of Open Access Journals (Sweden)

    Akakpo-Numado Gamedzi Komlatsè

    2014-01-01

    Full Text Available Background: Huge umbilical hernias (HUH are voluminous umbilical hernia (UH that are frequent in black African children. Several surgical techniques are used in their treatment for umbilical reconstruction, but techniques using skin flaps provide better aesthetic results. In this study, we presented our technique of umbilicoplasty in HUH, and its results. Patients and Methods: It is a retrospective study on children treated for HUH, from January 2012 to December 2013. The UH was called HUH when its basis diameter (BD exceeds 3 cm. Every HUH was characterised by its height, BD and morphology. Our technique was a two lateral flaps technique; the flaps are symmetrical and drawn so as to reconstitute the different parts of the umbilicus. The results were appreciated with criteria, including the peripheral ring and the central depression of the neo-umbilicus. Results : Twelve children were concerned (7 boys and 5 girls. Their mean age was 5 years and 6 months. The mean BD was 5.6 cm (extremes 3 and 8 cm, and the mean height of the HUH was 7.45 cm (extremes 3 and 9 cm. All underwent umbilicoplasty. In early post-operative period, two children presented a transitory subcutaneous hematoma. Late complications were granulation tissue with two children, and cheloid scar with one. With a mean follow-up of 10 months, we had 10 excellent results and two fair results according to our criteria. Conclusion: Our two lateral flaps umbilicoplasty is well-adapted to HUH in children. It is simple and assures a satisfactory anatomical and cosmetic result.

  6. DIAGNOSIS AND THERAPEUTIC CONSIDERATIONS OF UTERINE INFECTIONS IN DAIRY CATTLE CONSIDERACIONES DIAGNÓSTICAS Y TERAPÉUTICAS PARA INFECCIONES UTERINAS EN VACAS LECHERAS

    Directory of Open Access Journals (Sweden)

    Risco Carlos

    2009-05-01

    Full Text Available From an animal health-well being, welfare, and performance perspective, the postpartum period is comprised of an early window where acute health and cow survival is an issue with the development of septic metritis. Subsequently, sustained presence of endometritis is likely to be contributing to sub-fertility in lactating dairy cows with an overall herd pregnancy rate of approximately 16%. The challenge is to integrate on commercial dairies preventive medicine programs with reproductive management to improve herd fertility. Cows affected by periparturient disorders such as hypocalcemia, dystocia, and retained fetal membranes are more likely to contract uterine infections than cows that calve normally are. Thus, appropriate management of the transition period is critical in the prevention of uterine infections at the herd level. In addition, a postpartum program to monitor health to provide treatment to cows in the early stages of disease should be implemented.Desde el punto de vista del bienestar animal y de la perspectiva de productividad, el periodo postparto puede estar comprometido por una pequeña ventana durante el postparto temprano, en la cual la salud y supervivencia de las vacas es un problemática, debido a la presentación de metritis séptica. Esta se perpetuán subsecuentemente con la presentación de endometritis, la cual muy posiblemente contribuye con los patrones de sub-fertilidad en vacas lactantes, generando en general bajas tasas de preñez del 16 %. El reto es entonces integrar en las explotaciones comerciales un programa de medicina veterinaria preventiva con el manejo reproductivo, con el fin de mejorar la fertilidad del hato. Se ha descrito que las vacas que sufren problemas durante el periparto tales como hipocalcemia y retención de las membranas fetales son más susceptibles de contraer infecciones uterinas, comparadas con aquellas vacas que tienen un parto normal. Por ello un manejo apropiado del periodo de transici

  7. Modelo computacional para caracterización de células escamosas de citologías cérvico-uterinas

    Directory of Open Access Journals (Sweden)

    Martínez Abaunza Víctor Eduardo

    2005-12-01

    Full Text Available El trabajo se realizó entre el Grupo de Investigación en Ingeniería Biomédica (GIIB y el Grupo de Investigación en Patología Estructural, Funcional y Clínica de la Universidad Industrial de Santander (UIS, junto con la Facultad de Medicina de la Universidad Autónoma de Bucaramanga (UNAB; el objetivo principal es construir un modelo computacional que permita caracterizar las células presentes en una citología cérvico uterina, con el propósito de clasificarlas como normales o displásicas. Las láminas que contenían las muestras celulares las recolectaron los patólogos y se tomaron fotografías digitales por medio de una cámara de video acoplada a un microscopio y conectada a un dispositivo de adquisición. En la segmentación de las imágenes se utilizaron tres algoritmos de binarización que permitieron detectar los núcleos celulares; debido a que estos algoritmos presentaron fallas en la detección del citoplasma, se utilizó binarización manual. La descripción de la textura celular se logró con la distribución del histograma, en cada uno de los planos de color, y en los bordes se emplearon descriptores de Fourier. Se presentan los resultados de la primera fase, implementados en la clasificación e identificación de células normales. En las fases posteriores se aplicará la caracterización de cada uno de los estadios de las células clasificadas inicialmente como displásicas, para lograr discriminar las reactivas de las que realmente tienen cambios de lesión. Palabras clave: tratamiento de imágenes, morfología matemática, citología cérvico uterina, displasia, cáncer de cérvix.

  8. Função endotelial, perfusão uterina e fluxo central em gestações complicadas por Pré-Eclampsia

    Directory of Open Access Journals (Sweden)

    Augusto Henriques Fulgêncio Brandão

    2012-10-01

    Full Text Available FUNDAMENTO: A fisiopatologia da Pré-Eclampsia (PE é caracterizada por deficiência no processo de placentação, disfunção endotelial sistêmica e hiperfluxo do Sistema Nervoso Central (SNC. Do ponto de vista clínico, seria interessante determinar a ocorrência desses fenômenos antes do aparecimento das manifestações clínicas da doença, levantando a possibilidade de novos métodos de predição da PE. OBJETIVO: Comparar o processo de placentação, a função endotelial e o hiperfluxo do SNC em gestantes de alto risco para desenvolvimento de PE que posteriormente desenvolveram ou não a síndrome. MÉTODOS: Um total de 74 gestantes foi submetido ao exame de Dilatação Fluxo-Mediada (DFM da artéria braquial, dopplerfluxometria de artérias uterinas e oftálmica para avaliação da função endotelial, processo de placentação e hiperfluxo central, respectivamente. Os exames foram realizados entre 24 e 28 semanas de gestação e as pacientes foram acompanhadas até o puerpério para coleta de dados. RESULTADOS: Quinze pacientes tiveram a gestação complicada pela PE e 59 se mantiveram normotensas até o puerpério. Pacientes que subsequentemente desenvolveram PE apresentaram entre 24 e 28 semanas de gestação, maiores valores no índice de pulsatilidade das artérias uterinas e menores valores de DFM (p < 0,001 e p = 0,001, respectivamente. Entretanto, não houve diferença nos valores obtidos no índice de resistência da artéria oftálmica (p = 0,08. CONCLUSÃO: Os dados obtidos sugerem que a deficiência no processo de placentação e a disfunção endotelial precedem cronologicamente as manifestações clínicas da PE, o que não ocorre com o hiperfluxo do SNC.

  9. CMS ECAL Endcap (EE) - Preparatory work for umbilical noise studies

    CERN Multimedia

    Lodge, T

    2007-01-01

    Possible mapping solution, done inside connector, top and bottom sides of MB MB with umbilical + free pins, all identical until position on Dee known Then pins to connector in specific order for that position. All SC umbilicals to mating connector identical.

  10. Histomorphometry of umbilical vessels of intrauterine growth restricted neonates

    Directory of Open Access Journals (Sweden)

    Sangeeta S. Kotrannavar

    2016-01-01

    Conclusions: IUGR is associated with significant structural changes in umbilical vessels of full term neonates. These changes are more obvious in HUV than human umbilical artery (HUA. It can be detected prenatally and used as an indicator of impending IUGR. [Int J Reprod Contracept Obstet Gynecol 2016; 5(1.000: 129-134

  11. Umbilical cord blood transplantation: the first 25 years and beyond.

    Science.gov (United States)

    Ballen, Karen K; Gluckman, Eliane; Broxmeyer, Hal E

    2013-07-25

    Umbilical cord blood is an alternative hematopoietic stem cell source for patients with hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation. Initially, umbilical cord blood transplantation was limited to children, given the low cell dose infused. Both related and unrelated cord blood transplants have been performed with high rates of success for a variety of hematologic disorders and metabolic storage diseases in the pediatric setting. The results for adult umbilical cord blood transplantation have improved, with greater emphasis on cord blood units of sufficient cell dose and human leukocyte antigen match and with the use of double umbilical cord blood units and improved supportive care techniques. Cord blood expansion trials have recently shown improvement in time to engraftment. Umbilical cord blood is being compared with other graft sources in both retrospective and prospective trials. The growth of the field over the last 25 years and the plans for future exploration are discussed.

  12. Umbilical cord blood transplantation: A review of atricles

    Directory of Open Access Journals (Sweden)

    Asadi Amoly F

    1999-08-01

    Full Text Available Interest in umbilical cord blood as an alternative source of hematopietic stem cells is growing rapidly. Umbilical cord blood offers the clinician a source of hematopoietic stem cells that are readily available and rarely contaminated by latent viruses. Moreover, the collection of umbilical cord blood poses no risk to the donor. There is no need for general anesthesia or blood replacement and the procedure causes no discomfort. Current clinical experience suggests that the incidence of GVHD in umbilical cord blood transplantation is low. These results and associated laboratory findings pose intriguing possibilities for the future of umbilical cord blood stem cells in the setting of unrelated donor transplantation. There are other intriguing possibilities for example cord blood may be an optimal source of pluripotential stem cells for use in genetherapy.

  13. ADAPTACIÓN DEL ALGORITMO MARACAS PARA SEGMENTACIÓN DE LA ARTERIA CARÓTIDA Y CUANTIFICACIÓN DE ESTENOSIS EN IMÁGENES TAC

    Directory of Open Access Journals (Sweden)

    MARIA A. ZULUAGA

    2010-01-01

    Full Text Available En este artículo se describen las adaptaciones hechas al algoritmo MARACAS para seg- mentar y cuantificar estructuras vasculares en imágenes TAC de la arteria carótida. El al- goritmo MARACAS, que está basado en un modelo elástico y en un análisis de los valores y vectores propios de la matriz de inercia, fue inicialmente diseñado para segmentar una sola arteria en imágenes ARM. Las modificaciones están principalmente enfocadas a tratar las especificidades de las imágenes TAC, así como la presencia de bifurcaciones. Los algoritmos implementados en esta nueva versión se clasifican en dos niveles. 1. Los proce- samientos de bajo nivel (filtrado de ruido y de artificios direccionales, presegmentación y realce destinados a mejorar la calidad de la imagen y presegmentarla. Estas técnicas están basadas en información a priori sobre el ruido, los artificios y los intervalos típicos de niveles de gris del lumen, del fondo y de las calcificaciones. 2. Los procesamientos de alto nivel para extraer la línea central de la arteria, segmentar el lumen y cuantificar la es- tenosis. A este nivel, se aplican conocimientos a priori sobre la forma y anatomía de las estructuras vasculares. El método fue evaluado en 31 imágenes suministradas en el con- curso Carotid Lumen Segmentation and Stenosis Grading Grand Challenge 2009. Los resultados obtenidos en la segmentación arrojaron un coeficiente de similitud de Dice promedio de 80,4% comparado con la segmentación de referencia, y el error promedio de la cuantifi- cación de estenosis fue 14,4%.

  14. Síndrome de atrapamiento de la arteria poplítea con aneurisma: reporte de un caso Popliteal entrapment syndrome caused by an aneurism: Case report

    Directory of Open Access Journals (Sweden)

    Tania Buccolini

    2010-06-01

    Full Text Available La verdadera prevalencia del síndrome de atrapamiento de la arteria poplítea es desconocida; se estima en un 0.16%. Se considera la principal causa de claudicación intermitente en jóvenes deportistas sin factores de riesgo cardiovasculares. Se caracteriza por la compresión extrínseca de la arteria poplítea, ya sea por defecto anatómico de las estructuras músculo-tendinosas o por hipertrofia de los músculos gemelos, lo cual ocasiona el atrapamiento y síntomas de parestesias, frialdad y claudicación intermitente en la extremidad comprometida. La compresión crónica de la arteria puede llevar a daño irreversible con formación de trombos y aneurismas y a la consiguiente amputación de la extremidad, por lo que el diagnóstico y el tratamiento oportunos son de gran importancia para el paciente.The true prevalence of the popliteal artery entrapment syndrome is unknown, it is estimated to be 0.16%. It is considered as the main cause of intermittent claudication in young athletes without cardiovascular risk factors. It is characterized by the extrinsic compression of the popliteal artery either caused by defects of the muscle-tendon structures or by the hypertrophy of the gastrocnemius muscle leading to the arterial entrapment and symptoms of paresthesia, intermittent claudication and coldness of the affected limb. Chronic compression of the artery may lead to irreversible damage with formation of thrombi and aneurysms and the subsequent amputation of the limb. Therefore, correct diagnosis and treatment are of great importance for the patient.

  15. A Histerossonografia na Avaliação da Cavidade Uterina em Pacientes Menopausadas Sonohysterography in the evaluation of the uterine cavity in postmenopausal women

    Directory of Open Access Journals (Sweden)

    Benito Pio Vitório Ceccato Júnior

    2002-09-01

    Full Text Available Objetivos: avaliar a acuidade diagnóstica da histerossonografia como método de avaliação da cavidade uterina em pacientes menopausadas com cavidade uterina alterada à ultra-sonografia endovaginal convencional. Métodos: este estudo consistiu na avaliação de 99 pacientes menopausadas com cavidade uterina anormal à ultra-sonografia endovaginal convencional, caracterizada por espessura endometrial maior ou igual a 5 mm em pacientes sem terapia de reposição hormonal, ou espessura endometrial maior ou igual a 8 mm em pacientes em terapia de reposição hormonal, com sangramento irregular. Estas pacientes foram submetidas à histerossonografia e após, foram obtidas amostras para avaliação histopatológica por biópsia dirigida por histeroscopia em 92 pacientes, biópsia endometrial em quatro pacientes e histerectomia em três pacientes. Os resultados da histerossonografia foram comparados com os resultados do exame histopatológico, considerado como "padrão-ouro". Resultados: houve oito casos de cavidade uterina normal e 20 casos de atrofia endometrial e a histerossonografia teve altos níveis de especificidade (97,8 e 97,5% e baixa sensibilidade (35 e 25%. Houve altos níveis de sensibilidade (92,3 e 75,0% e especificidade (94,1 e 97,9% em pólipos (65 casos e miomas submucosos (quatro casos. Houve três casos de câncer de endométrio e a histerossonografia teve sensibilidade e especificidade de 100%. Conclusões: a histerossonografia mostrou boa acuidade no diagnóstico de doenças focais (pólipos endometriais e miomas submucosos, com altos níveis de sensibilidade e especificidade. Houve três casos de câncer endometrial, e a histerossonografia diagnosticou corretamente todos eles. Mostrou também ser método acurado para excluir anormalidades endometriais. Entretanto, nos casos de espessamento endometrial difuso, a acuidade é baixa, porque endométrios atróficos ou normais freqüentemente aparecem como tendo espessamento difuso

  16. Colgajo libre córtico-perióstico de la arteria genicular descendente en el tratamiento de la seudoartritis distal de tibia

    OpenAIRE

    2010-01-01

    Presentamos un caso de un varón de 35 años con pseudoartrosis aséptica de tibia distal con escaso defecto óseo, intervenido previamente mediante recambio del material de osteosíntesis e injerto de cresta iliaca, que fracasó. Tras estudio de las diferentes opciones de tratamiento, se le propuso estabilizar el foco mediante enclavado endomedular y aumentar la capacidad osteogénica con un colgajo córtico-perióstico de la arteria genicular descendente, según la técnica de Sakai. Discusión: El man...

  17. Evaluation of methods to test chemicals suitability for umbilical applications

    Energy Technology Data Exchange (ETDEWEB)

    Allenson, S. J.; Lindeman, O. E.; Cenegy, L. M.

    2006-03-15

    Offshore deep-water projects are increasingly deploying chemicals to sub-sea wellheads through umbilical lines. There is no margin for error in umbilical chemical treatment programs since any flow blockage in a sub-sea line would result in a multi-million dollar problem. Chemicals for umbilical delivery must also meet strict requirements in their performance and especially their handling properties. Umbilical delivery must be effective at low concentrations in preventing corrosion, scale, hydrates, asphaltenes, paraffin and a host of other problems. Chemical transiting an umbilical can experience pressures as high as 15,000 psi and temperatures ranging from near 0 deg C to greater than 120 deg C. Since some umbilicals are as long as 80 km, a week or more can elapse from the time the chemical is injected at the platform until it reaches the sub-sea well. Therefore, the chemical must not only be stable under all temperature and pressure conditions that it may experience in the umbilical line, it must also be stable under these conditions for a long period of time. Since many umbilical lines actually terminate into sub-sea valves and connectors that are only a few hundred microns in diameter, it is critical that the injected chemical have a low viscosity at sub-sea temperatures and pressures and that it be completely free of particles. These issues present substantial challenges in formulating and manufacturing chemicals for umbilical applications that must be addressed prior to approval of a product for use. Each of these challenges was taken into consideration and a series of tests were developed to assure reliable chemical pump ability through an umbilical line. The tests developed included enhanced formulation stability tests under umbilical temperature and pressure conditions, NAS Class rating, extensive material compatibility testing to include all metals and elastomers that may be used in umbilical injection systems and comprehensive physical property testing

  18. Origen y morfología de la arteria braquial profunda en 14 cadáveres de la universidad de costa rica y de la universidad de ciencias médicas

    Directory of Open Access Journals (Sweden)

    Eduardo Delvo

    2012-09-01

    Full Text Available En este estudio se trata de observar la variabilidad del origen y morfología de la Arteria Braquial Profunda. Se utilizaron 14 cadáveres, a los cuáles se les midió el largo y diámetro de la Arteria Braquial Profunda antes de su bifurcación en Arteria Colateral Radial y Colateral Media en ambos brazos. El 21,4% presentó el origen de la Arteria junto con ramas musculares, el 14,3% de manera bilateral un origen común de la Arteria Braquial Profunda y la Arteria Circunfleja Humeral Posterior,el 7,2% una bifurcación temprana de la Arteria Braquial en Arterial Radial y Ulnar a nivel del tercio proximal del antebrazo y el 7,2% la misma variación a nivel del tercio medio. La longitud y diámetro de la Arteria en el estudio en promedio fue de 84,78 mm con un diametro de 1,66 mm en la izquierda y de 83,26 mm con un diametro de1,68 mm en la derecha, las diferencias presentadas no son estadísticamente significativas. El conocimiento de las diferencias anatómicas s de importancia en la practica clínica y quirúrgicaIn this review the objetive was to analize the variability of the origen and morphology of the Deep Braquial Artery. For it we used 14 bodies, in which we measure the lenght and diameter of the selected artery before the bifurcation of the radial collateral artery and medial collateral artery in both arms. The 21,4% of the cases the origen was presented along with the muscular branches, in the 14,3% was presented bilateral a common origen of Deep Braquial Artery and Posterior Humeral Circumflex Artery, in the 7,2% was presented an early bifurcation of Deep Braquial Artery in radial and ulnar at the third proximal of the forearm, in 7,2% the same modification was observed but at the middle third of the forearm. The lenght and diameter of the artery in promedy found was 84,78mm with a diameter of 1,66mm in the left side and 83,26mm with a diameter of 1,68mm in the right side, the diference found, were not of statiscally significant. The

  19. Umbilical properties of spacelike co-dimension two submanifolds

    CERN Document Server

    Cipriani, Nastassja; Van der Veken, Joeri

    2016-01-01

    For Riemannian submanifolds of a semi-Riemannian manifold, we introduce the concepts of \\emph{total shear tensor} and \\emph{shear operators} as the trace-free part of the corresponding second fundamental form and shape operators. The relationship between these quantities and the umbilical properties of the submanifold is shown. Several novel notions of umbilical submanifolds are then considered along with the classical concepts of totally umbilical and pseudo-umbilical submanifolds. Then we focus on the case of co-dimension $2$, and we present necessary and sufficient conditions for the submanifold to be umbilical with respect to a normal direction. Moreover, we prove that the umbilical direction, if it exists, is unique ---unless the submanifold is totally umbilical--- and we give a formula to compute it explicitly. When the ambient manifold is Lorentzian we also provide a way of determining its causal character. We end the paper by illustrating our results on the Lorentzian geometry of the Kerr black hole.

  20. Scar endometriosis developing after an umbilical hernia repair with mesh.

    Science.gov (United States)

    Majeski, James; Craggie, James

    2004-05-01

    A 44-year-old female was initially evaluated for a 3-cm umbilical hernia, which developed after a laparoscopic myomectomy performed seven years prior. The umbilical hernia was repaired using a synthetic mesh. Eight months after the umbilical hernia repair, the patient returned with chronic pain in a 3-cm raised mass originating from the umbilical hernia repair incision. The mass and mesh were surgically removed. The umbilical fascial defect was repaired with a primary fascia-to-fascia closure and the umbilicus was reconstructed from adjacent skin. The mass was found histologically to be endometriosis and fascial scarring with a foreign body reaction to synthetic mesh. Umbilical endometriosis developed either from peritoneal endometrial seeding from a laparoscopic myomectomy or from metaplasia of multipotential cells, which developed into endometriosis due to inflammatory stimulation by the synthetic mesh. Synthetic mesh probably should be avoided in the surgical repair of a laparoscopically caused umbilical hernia in a premenopausal female especially if there is a history of pelvic endometriosis.

  1. Umbilical cord and visceral hemangiomas diagnosed in the neonatal period

    Science.gov (United States)

    Iglesias-Deus, Alicia; Pérez-Muñuzuri, Alejandro; Urisarri, Adela; Bautista-Casasnovas, Adolfo; Couce, Maria-Luz

    2016-01-01

    Abstract Background: Umbilical cord hemangioma is very rare and may not be detected prenatally. However, it should be considered in differential diagnosis with other umbilical masses because it can cause significant morbidity. Methods: We report the case of a newborn referred with suspected omphalitis and umbilical hernia. Results: Physical examination showed an irreducible umbilical tumor, the size of olive, with dubious secretion. The initial suspected diagnosis was urachal or omphalomesenteric duct remnants. Abdominal ultrasound and magnetic resonance imaging showed an umbilical and a mesenteric mass. Tumor markers were negative. A definitive diagnosis of umbilical cord and intestinal hemangioma was established after surgical excision and histologic examination of the umbilical mass. Propranolol was prescribed due to the extent of the intestinal lesion. Conclusion: This report highlights the diagnostic challenges of hemangiomas in unusual locations. Apart from the rarity of these tumors, few tests are available to guide diagnosis, and surgery and histologic examination are generally required for a definitive diagnosis. Finally, it is essential to rule out associated malformations and hemangiomas in other locations. PMID:27759656

  2. Surgical anatomy and morphologic variations of umbilical structures.

    Science.gov (United States)

    Fathi, Amir H; Soltanian, Hooman; Saber, Alan A

    2012-05-01

    The umbilicus is the main access route to the abdominal cavity in laparoscopic surgeries. However, its anatomical configuration is rarely studied in the surgical and anatomical literature. With introduction of laparoendoscopic single-site surgery and considering the significant number of primary and postoperative umbilical hernias, we felt the necessity to comprehensively study the umbilical structures and analyze their protective function against hernias. Twenty-four embalmed cadavers were studied in the anatomy laboratory of Case Western Reserve University. Round hepatic, median and medial ligaments, umbilical ring, umbilical and umbilicovesicular fasciae, and pattern of attachment to the ring were dissected and measured. Mean age was 82.1 years, ranging between 56 and 96 years, with a male-to-female ratio of 1.4:1. Ninety-two per cent was white and 8 per cent black adults. According to shape and attachment pattern of ligaments, umbilical ring is classified into five types. Hernia incidence was 25 per cent. All hernia cases lacked the umbilical fascia and the round hepatic ligament was not attached to the inferior border of the ring. The umbilical ring and its morphologic relation with adjacent ligaments are described and classified into five types. In contrary to sparse existing literature, we propose that umbilical fascia is continuation and condensation of umbilicovesicular rather than transversalis fascia. It was absent in cadavers forming conjoined median and medial ligaments with a single insertion site to the ring. Round ligament insertion to the inferior border of the ring provides another protective factor. These two protective measures were absent in all the observed umbilical hernias.

  3. MANAGEMENT OF OMPHALOPHLEBITIS AND UMBILICAL HERNIA IN THREE NEONATAL GIRAFFE (GIRAFFA CAMELOPARDALIS).

    Science.gov (United States)

    Selig, Michael; Lewandowski, Albert; Burton, Michael S; Ball, Ray L

    2015-12-01

    Umbilical disorders, including omphalophlebitis, omphaloarteritis, external umbilical abscesses, urachal abscesses, patent urachus, and umbilical hernias, represent a significant challenge to the health and well-being of a neonate. The three neonatal giraffe (Giraffa camelopardalis) in this report were evaluated for umbilical swellings. Two developed omphalophlebitis, and one had an uncomplicated umbilical hernia. Omphalophlebitis is an inflammation and/or infection of the umbilical vein. Giraffe calves with a failure of passive transfer may be predisposed and should be thoroughly evaluated for the condition. Umbilical hernias result from a failure of the umbilical ring to close after parturition or from malformation of the umbilical ring during embryogenesis. These problems were surgically corrected for all three individuals, although one died due to postsurgical complications. The risks involved include anesthetic complications, surgical dehiscence, and maternal rejection. Early detection and surgical intervention are recommended for the correction of omphalophlebitis and umbilical hernias in neonatal giraffe.

  4. Doppler ultrasound scan during normal gestation: umbilical circulation; Ecografia Doppler en la gestacion normal: circulacion umbilical

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz, T.; Sabate, J.; Martinez-Benavides, M. M.; Sanchez-Ramos, J. [Hospital Virgen Macarena. Sevilla (Spain)

    2002-07-01

    To determine normal umbilical circulation patterns by means of Doppler ultrasound scan in a healthy gestating population without risk factors and with normal perinatal results, and to evaluate any occurring modifications relative to gestational age by obtaining records kept during pregnancy. One hundred and sixteen pregnant women carrying a single fetus have been studied. These women had no risk factors, with both clinical and analytical controls, as well as ultrasound scans, all being normal. There were performed a total of 193 Doppler ultrasound scans between weeks 15 and 41 of gestation, with blood-flow analysis in the arteries and vein of the umbilical cord. The obtained information was correlated with parameters that evaluate fetal well-being (fetal monitoring and/or oxytocin test) and perinatal result (delivery type, birth weight, Apgar score). Statistical analysis was performed with the programs SPSS 6.0.1 for Windows and EPIINFO 6.0.4. With pulsed Doppler, the umbilical artery in all cases demonstrated a biphasic morphology with systolic and diastolic components and without retrograde blood flow. As the gestation period increased, there was observed a progressive decrease in resistance along with an increase in blood-flow velocity during the diastolic phase. The Doppler ultrasound scan is a non-invasive method that permits the hemodynamic study of umbilical blood circulation. A knowledge of normal blood-flow signal morphology, as well as of the normal values for Doppler indices in relation to gestational age would permit us to utilize this method in high-risk pregnancies. (Author) 30 refs.

  5. Tensile Stiffness Analysis on Ocean Dynamic Power Umbilical

    Institute of Scientific and Technical Information of China (English)

    汤明刚; 阎军; 王野; 岳前进

    2014-01-01

    Tensile stiffness of ocean dynamic power umbilical is an important design parameter for functional implementation and structural safety. A column with radial stiffness which is wound by helical steel wires is constructed to predict the tensile stiffness value of umbilicals in the paper. The relationship between the tension and axial deformation is expressed analytically so the radial contraction of the column is achieved in the relationship by use of a simple finite element method. With an agreement between the theoretical prediction and the tension test results, the method is proved to be simple and efficient for the estimation of tensile stiffness of the ocean dynamic power umbilical.

  6. Procedure for action in the donation of umbilical cord blood

    Directory of Open Access Journals (Sweden)

    Antonio Herrera Gómez

    2012-05-01

    Full Text Available Stem cells are candidates for donation and transplantation in certain diseases, such as treatment of choice. Stem cells from umbilical cord blood are of particular interest as a gift, for many reasons. It should be noted that the umbilical cord blood is a single, limited source of hematopoietic progenitor cells, and the eventual success of a transplant, cellular viability and retained sample are critical, so the extraction process transport and cryopreservation must be performed under strict quality control criteria. Objective: To describe the procedure extacción umbilical cord blood to be carried out in units of delivery, to ensure quality results.

  7. Aneurisma idiopático de la arteria pulmonar. Presentación de un caso y revisión de algunos aspectos clínicos.

    Directory of Open Access Journals (Sweden)

    Rafael Pila Pérez

    2011-10-01

    Full Text Available Se presenta el caso de un paciente masculino de 38 años de edad, fumador inveterado, con antecedentes de hipertensión arterial esencial, que ingresó en el Hospital Universitario Manuel Ascunce Doménech, de Camagüey, por presentar dolor precordial intenso. En la radiografía de tórax se encontró una imagen opaca bien delimitada a nivel parahiliar izquierdo, motivo por el cual se le practicaron diversas exploraciones complementarias como tomografía axial computarizada y ecocardiografía que revelaron la presencia de una dilatación aneurismática de la arteria pulmonar izquierda. El diagnóstico se concluyó como un aneurisma idiopático de la arteria pulmonar. Debido a que el paciente mejoró clínicamente y el tratamiento quirúrgico entrañaba mucho riesgo para su vida, se optó por el manejo conservador y control periódico.

  8. Predição da restrição do crescimento fetal pela medida da altura uterina Prediction of fetal growth restriction by measurement of uterine height

    Directory of Open Access Journals (Sweden)

    Silvio Martinelli

    2004-06-01

    Full Text Available OBJETIVO: avaliar o emprego da medida da altura uterina para o diagnóstico da restrição do crescimento fetal (RCF, empregando como padrão curvas conhecidas de evolução da altura uterina do próprio serviço. MÉTODOS: entre julho de 2000 e fevereiro de 2003, 238 gestantes de alto risco foram submetidas a medidas de altura uterina, da 20ª à 42ª semana de gestação. Todas possuíam idade gestacional confirmada por ultra-sonografia precoce. Cinqüenta (21,0% gestantes tiveram recém-nascidos pequenos para a idade gestacional. O mesmo observador realizou 1617 medidas de altura uterina, com fita métrica, da borda superior da sínfise púbica ao fundo uterino. A confirmação do diagnóstico de RCF foi dada após o nascimento pela curva de Ramos. Para a análise estatística, as gestantes foram comparadas segundo o peso dos recém-nascidos, por meio do teste exato de Fisher ou teste não paramétrico de Kruskal-Wallis, quando aplicável. Foram calculados: sensibilidade (S, especificidade (E, valor preditivo positivo (VPP e negativo (VPN para o diagnóstico de RCF. Para a análise dos valores contínuos foi utilizado o teste para duas proporções com aproximação normal. RESULTADOS: para a ocorrência de RCF, considerando-se uma medida de altura uterina abaixo do percentil 10 para a idade gestacional, S foi de 78%, E de 77,1%, VPP de 47,6% e VPN de 92,9%. Utilizando como limite o percentil 5, foram obtidos S = 64%, E = 89,9%, VPP = 62,7% e VPN = 90,4%, para o diagnóstico da RCF. CONCLUSÃO: medida de altura uterina abaixo do percentil 10 para a idade gestacional, pela curva local, mostra-se como bom teste para o rastreamento da RCF.OBJECTIVE: to evaluate the measurement of uterine height in order to predict fetal growth restriction (FGR, according to a local curve. METHODS: from July 2000 to February 2003, 238 high-risk pregnant women were submitted to uterine height measurements between the 20th and the 42nd week of gestation. The

  9. The prevalence of umbilical and epigastric hernia repair

    DEFF Research Database (Denmark)

    Burcharth, J; Pedersen, M.S.; Pommergaard, H C;

    2015-01-01

    PURPOSE: Umbilical and epigastric hernia repair are common surgical procedures; however, the nationwide gender and age-specific prevalence of these repairs is unknown, and this knowledge could form the basis for new studies. METHODS: A nationwide register-based study covering all people living...... in Denmark on December 31st, 2010 was performed. Within this population all umbilical and epigastric hernia repairs from January 1st, 2006 to December 31st, 2010 were identified using data from the Danish National Hospital Register, and 5-year prevalence estimates were calculated. RESULTS: The study...... population covered 5,639,885 persons (49 % males). A total of 10,107 patients (68 % males) were operated for an umbilical hernia and 2412 patients (55 % males) were operated for an epigastric hernia. The age-specific 5-year prevalence differed for both hernia types. The highest 5-year prevalence of umbilical...

  10. Estudio macro-microscópico de la involución uterina postparto en alpacas - Macro and microscopic of uterine involution postpartum in alpacas

    Directory of Open Access Journals (Sweden)

    MVZ. Augusto Excelmes Loza. Puno-Perú 2005

    2006-07-01

    Full Text Available El presente estudio se llevo a cabo en el Laboratorio de Histología y Embriología de la Facultad de Medicina Veterinaria y Zootecnia de la Universidad Nacional del Altiplano; con alpacas provenientes de la Rural Alianza E.P.S. (4,140m.s.n.m, Centro Experimental Quinsachata-INIA (4,050 m.s.n.m y el Centro de Investigación y Producción La Raya (4,130 m.s.n.m, cuyo objetivo fue el estudio del proceso de la involución uterina post parto en la alpaca, desde el parto hasta los 30dpp. Para tal propósito se estudiaron 34 alpacas multíparas de 4 a 6 años de edad. Los resultados fueron: Macroscópicamente: la perdida de peso del útero fue de: 71.07% (385,25g, 25.54% (138.55g y 3.42% (18.6g al primer, segundo y tercer periodo de la involución uterina. La reducción de Peso del cuerno uterino derecho fue de: 55.26% (37.55g, 38.63% (26.25g y 6.11% (4.15g al primer segundo y tercer periodo respectivamente. La secuencia de la perdida de peso del cuerno uterino izquierdo fue de: 75.50% (159.5g, 19.58% (41.25g, y 4.92% (10.40g al primer, segundo y tercer periodo sucesivamente. El descenso de Peso del cuerpo del útero fue de: 76.60% (87.25g, 17.08% (19.45g y 6.32% (7.2g al primer, segundo y tercer periodo sucesivamente. El Peso de reducción gradual de la cervix fue de: 68% (47,15g, 26,10% (18,00g y 5,51% (3,8g al primer, segundo y tercer periodo respectivamente. This study was carried out in the Histology and Embriology laboratory at the Medicine Veterinary and Zootecny of the Altiplano National University, with alpacas coming from the EPS Rural Alliance (4140 m.a.s.l., Quimsachata Research Center (4050 m.a.s.l. and the Raya Research Center (4130 m.a.s.l. whose objective was the study the process of the uterine involution after parturition from day 0 to 30. For such purpose 34 multiparous alpacas from 4 to 6 year old were selectec. The results were: Macroscopically the uterusweight lost 71,07% (385,25g, 25,54% (138,55g and 3,42% (18,6g at first

  11. Acurácia da histeroscopia na avaliação da cavidade uterina em pacientes com sangramento uterino pós-menopausa

    Directory of Open Access Journals (Sweden)

    Machado Maria Karenina N.

    2003-01-01

    Full Text Available OBJETIVO: investigar a acurácia da histeroscopia como método de estudo da cavidade uterina de pacientes com sangramento na pós-menopausa. MÉTODO: trata-se de estudo transversal, que consistiu na avaliação de 78 prontuários de pacientes menopausadas com queixa de sangramento, no período de janeiro de 2000 a junho de 2002 no Centro Estadual de Oncologia do Estado da Bahia, submetidas à histeroscopia com biópsia de endométrio. Os achados histeroscópicos foram classificados como benignos (miomas, pólipos, atrofia, normal e suspeitos (espessamento, hiperplasias e câncer e os achados histopatológicos como benignos (miomas, pólipos, atrofia, hiperplasia típica e malignos (hiperplasia atípica e câncer. Os resultados da histeroscopia foram comparados com os exames histopatológicos. RESULTADOS: em relação aos achados suspeitos (espessamento, hiperplasias e câncer, a sensibilidade da histeroscopia foi de 85,7% e a especificidade de 88,7%, quando comparados à histopatologia. O valor preditivo positivo foi de 42,8% e o negativo 98,4%. A razão de probabilidades do teste positivo e a razão de probabilidades do teste negativo foram respectivamente 7,6 e 0,16. A acuidade da histeroscopia foi de 88,4% e o índice kappa 0,5. CONCLUSÃO: a histeroscopia isoladamente não apresentou, no presente estudo, acurácia aceitável, reforçando o conceito de que sua principal vantagem é dirigir a biópsia, devendo sempre estar associada ao diagnóstico histopatológico.

  12. Estudio macro-microscópico de la involución uterina postparto en Alpacas (Macro and microscopic of uterine involution postpartum in alpacas summary

    Directory of Open Access Journals (Sweden)

    MVZ. Augusto Excelmes Loza.

    2006-04-01

    Full Text Available El presente estudio se llevo a cabo en el Laboratorio de Histología y Embriología de la Facultad de Medicina Veterinaria y Zootecnia de la Universidad Nacional del Altiplano; con alpacas provenientes de la Rural Alianza E.P.S. (4,140m.s.n.m, Centro Experimental Quinsachata-INIA (4,050 m.s.n.m y el Centro de Investigación y Producción La Raya (4,130 m.s.n.m, cuyo objetivo fue el estudio del proceso de la involución uterina post parto en la alpaca, desde el parto hasta los 30dpp. Para tal propósito se estudiaron 34 alpacas multíparas de 4 a 6 años de edad. Los resultados fueron: Macroscópicamente: la perdida de peso del útero fue de: 71.07% (385,25g, 25.54% (138.55g y 3.42% (18.6g al primer, segundo y tercer periodo de la involución uterina. La reducción de Peso del cuerno uterino derecho fue de: 55.26% (37.55g, 38.63% (26.25g y 6.11% (4.15g al primer segundo y tercer periodo respectivamente. La secuencia de la perdida de peso del cuerno uterino izquierdo fue de: 75.50% (159.5g, 19.58% (41.25g, y 4.92% (10.40g al primer, segundo y tercer periodo sucesivamente. El descenso de Peso del cuerpo del útero fue de: 76.60% (87.25g, 17.08% (19.45g y 6.32% (7.2g al primer, segundo y tercer periodo sucesivamente. El Peso de reducción gradual de la cervix fue de: 68% (47,15g, 26,10% 18,00g y 5,51% (3,8g al primer, segundo y tercer periodo respectivamente. Histológicamente: durante los primeros días la superficie uterina es irregular y presenta proyecciones endometriales de aspecto fungiforme y esta cubierto por células pavimentosas, estroma con la presencia de linfocitos, macrófagos y fibroblastos, glándulas reducidas en su diámetro. A partir del sexto día, muestra cambio en el regenerativo, el epitelio de hace predominantemente cúbico, Del sexto al doceavo día el epitelio continua irregular con pequeñas áreas con células epiteliales pavimentosas y cúbicas, lo cual coincide con el cambio en el peso del útero en forma significativa

  13. Ensayo de irritabilidad vaginal a un producto natural, obtenido a partir de Rhizophora mangle L. destinado al tratamiento de infecciones uterinas.

    Directory of Open Access Journals (Sweden)

    Félix Agüero, Carlos Bulnes, Reina Durand y Liseth García.

    2005-06-01

    Full Text Available En las últimas décadas, se observa un incremento en la tendencia a obtener productos de origen natural para el tratamiento de afecciones en animales y humanos. Una de las fuentes naturales explotadas en Cuba con este fin es la planta Rhizophora mangle L. conocida comúnmente como Mangle rojo. Sobre los resultados obtenidos en investigaciones previas, nos trazamos como objetivo de nuestro trabajo desarrollar un ensayo para evaluar el potencial irritante de una formulación de Rhizophora mangle L. como medicamento candidato al tratamiento de infecciones uterinas. El ensayo se realizó bajo los procedimientos establecidos en la norma ISO 10993-10. “Biological evaluation of medical devices. Part 10: Test for irritation and sensitization. European Committee for Standarization”. Se cumplieron los principios de las Buenas Prácticas de Laboratorio y los principios éticos para evitar sufrimiento a los animales durante la experimentación. El protocolo de investigación fue aprobado por el Comité Institucional de Ética del CENSA. Como resultado se observó ligera congestión e infiltración leucocitaria. Los índices de irritabilidad fueron de 4.0, 3.1, 2.3 y 0.5, para las concentraciones de 16, 24, 32 y 100 mg/mL, respectivamente. El producto no fue irritante para la mucosa vaginal y se observó una disminución del indicador en la medida que se incrementa la concentración de la formulación.

  14. Open safety pin ingestion presenting as incarcerated umbilical hernia.

    Science.gov (United States)

    Mirza, Bilal; Sheikh, Afzal

    2011-09-01

    Foreign body ingestion is common in children. Sharp foreign bodies are potentially harmful and can result various complications. An 8-month-old infant presented with incarcerated umbilical hernia. With a suspicion of strangulation, operation was performed that revealed a loop of ileum being stuck in the umbilical defect. The loop of ileum was freed from the umbilicus which demonstrated open ends of safety pin piercing out of bowel lumen. The enterotomy followed by removal of safety pin was performed.

  15. Open Safety Pin Ingestion Presenting as Incarcerated Umbilical Hernia

    OpenAIRE

    Bilal Mirza; Afzal Sheikh

    2011-01-01

    Foreign body ingestion is common in children. Sharp foreign bodies are potentially harmful and can result various complications. An 8-month-old infant presented with incarcerated umbilical hernia. With a suspicion of strangulation, operation was performed that revealed a loop of ileum being stuck in the umbilical defect. The loop of ileum was freed from the umbilicus which demonstrated open ends of safety pin piercing out of bowel lumen. The enterotomy followed by removal of safety pin was p...

  16. Open Safety Pin Ingestion Presenting as Incarcerated Umbilical Hernia

    Directory of Open Access Journals (Sweden)

    Bilal Mirza

    2011-11-01

    Full Text Available Foreign body ingestion is common in children. Sharp foreign bodies are potentially harmful and can result various complications. An 8-month-old infant presented with incarcerated umbilical hernia. With a suspicion of strangulation, operation was performed that revealed a loop of ileum being stuck in the umbilical defect. The loop of ileum was freed from the umbilicus which demonstrated open ends of safety pin piercing out of bowel lumen. The enterotomy followed by removal of safety pin was performed.

  17. Distribuição da altura uterina ao longo da gestação em uma coorte brasileira: comparação com a curva de referência do Centro Latino-Americano de Perinatologia

    OpenAIRE

    Oppermann, Maria Lúcia Rocha; Duncan, Bruce Bartholow; Mengue, Sotero Serrate; Ramos, José Geraldo Lopes; Serruya,Suzanne Jacob; Schmidt, Maria Inês

    2006-01-01

    OBJETIVOS: descrever, em gestantes do Estudo Brasileiro do Diabetes Gestacional (EBDG), a distribuição da altura uterina de acordo com a idade gestacional e validar a curva do Centro Latino-Americano de Perinatologia (CLAP), curva de referência para a predição de anormalidades do crescimento fetal. MÉTODOS: o EBDG é uma coorte de 5564 gestantes, com mais de 19 anos, seguidas até e após o parto. Entrevistas e medidas antropométricas padronizadas foram feitas no arrolamento entre a 20ª e a 28ª ...

  18. Infecção do sítio cirúrgico em pacientes submetidas à cesárea com sutura uterina exteriorizada versus sutura in situ: ensaio clínico randomizado

    OpenAIRE

    Cristina Coutinho de Albuquerque Neiva Coêlho, Isabela

    2007-01-01

    Objetivos: Comparar a sutura uterina extra-abdominal com a sutura in situ na cesárea. Métodos: Foi realizado um ensaio clínico randomizado no IMIP (Recife, Brasil). Os critérios de inclusão foram indicação de cesárea e idade gestacional > 24 semanas. Pacientes com duas ou mais cesáreas anteriores, corioamnionite, hemorragias, incapacidade para consentir e cirurgia abdominal prévia foram excluídas. As variáveis analisadas foram náuseas, vômitos, média do tempo cirúrgico, perda s...

  19. Efecto, en un modelo murino, de dos polisacáridos sulfatados sobre la producción de citoquinas por células NK uterinas y de sangre periférica

    OpenAIRE

    Angela Patricia Cadavid Jaramillo; Beatriz Peña; Julio César Bueno Sánchez

    2000-01-01

    Las células asesinas naturales (NK) uterinas son una subpoblación diferente a las de sangre periférica, expresan los marcadores CD56bright y CD16- VALIDACIÓN DE LA CITOLOGIA CÉRVICO UTERINA CONVENCIONAL CON PRUEBA DE REFERENCIA HISTOPATOLÓGICA EN LA IDENTIFICACIÓN DE CÁNCER ESCAMOCELULAR INVASOR

    OpenAIRE

    García A,Ernesto; Díaz P,Julio; Melo U,Mario; Parra F,Fabián; Vera C,Lina; Orozco V,Luis

    2006-01-01

    Antecedentes: La citología cérvico uterina convencional (CCUC) es la prueba de tamizaje más empleada en la detección del cáncer de cuello uterino, sin embargo su calidad es discutida. Objetivo: Evaluar el rendimiento de la CCUC en el tamizaje de cáncer escamocelular invasor de cuello uterino. Métodos: Fueron seleccionadas 1980 usuarias de la Liga Santandereana de Lucha Contra el Cáncer. Siguiendo un muestreo prospectivo se realizó un análisis estadístico para validar la CCUC en el diagnóstico...

  1. Transplante de sangue de cordão umbilical - SCU Umbilical cord blood transplantation

    Directory of Open Access Journals (Sweden)

    Celso A. Rodrigues

    2010-05-01

    Full Text Available A frequente utilização de sangue de cordão umbilical - SCU como fonte de células- tronco hematopoéticas - CTH, tanto em crianças, como em adultos, que não dispõem de doador na família, tem levado ao estabelecimento da padronização de critérios em sua seleção, objetivando a obtenção de melhores resultados. A escolha da unidade de SCU deve basear-se no número total de células nucleadas e no número de diferenças de antígenos leucocitários humanos (HLA. Diante de uma unidade com celularidade mínima, deve-se considerar a possibilidade da utilização de duplo cordão. Frente a mais de uma unidade com características semelhantes, a realização da contagem de células CD34 e da compatibilidade ABO, assim como a qualidade e a rapidez para obtenção da unidade, podem definir a escolha.The frequent use of umbilical cord blood as the source of hematopoietic stem cells, both in children and adults who do not have related donors, has led to the establishment of a better standardization of selection criteria aiming at improving the results. The choice of the umbilical cord blood unit should be based on the total number of nucleated cells and the number of differences in the human leukocyte antigen (HLA system. When a unit has minimal cellularity, the use of a double cord blood transplant should be considered. When two or more units have similar characteristics, the choice may be determined by the CD34 count, ABO compatibility and the quality and speed to obtain the unit.

  2. Rupture of hepatic artery aneurysm associated with ischemic hepatitis Rotura de arteria hepática aneurismática asociada con hepatitis isquémica

    Directory of Open Access Journals (Sweden)

    V.M. Santos

    2010-08-01

    Full Text Available Hepatic artery aneurysms are scarcely reported, mainly because of non-specific symptoms. More often, they are incidental findings during imaging studies to investigate other acute or chronic abdominal conditions. These aneurysms are usually detected in the sixth decade of life, predominantly among males. We report the case of a 69 year-old female with an unsuspected huge hepatic artery aneurysm associated with ischemic hepatitis. Suspicion of aneurysm arose during imaging studies to clarify the origin of jaundice and abdominal pain. After establishment of the diagnosis, but before open surgery, there was a spontaneous rupture of the aneurysm, which caused hemoperitoneum and death. The necropsy study confirmed ischemic hepatitis. Hepatic artery aneurysms are second among the visceral aneurysms, and may cause abdominal pain, jaundice, and hemorrhagic events. One should suspect abdominal aneurysms in elderly patients with unclear abdominal pain, and this hypothesis should be ruled out by imaging studies.La publicación de trabajos sobre aneurismas en la arteria hepática es escasa, debido a los síntomas no específicos y a que constituyen hallazgos incidentales durante investigación de otras condiciones abdominales agudas o crónicas. Estos aneurismas son más frecuentes en varones y en la sexta década de la vida. Presentamos el caso de una mujer de 69 años de edad que ingresa en el hospital con un aneurisma de arteria hepática no sospechado previamente, asociado con hepatitis isquémica. La sospecha de aneurisma empezó durante estudio de imágenes para aclaramiento del origen de ictericia y dolor abdominal. Después de confirmado el diagnóstico, pero antes de la operación planeada, ocurrió rotura espontánea del aneurisma causando hemoperitoneo y muerte. El estudio de necropsia confirmó hepatitis isquémica. Los aneurismas de la arteria hepática son los segundos entre los aneurismas viscerales y pueden causar dolor abdominal, ictericia

  3. Arteria poplitea afklemningssyndrom

    DEFF Research Database (Denmark)

    Lyndrup, Peter; Meyer, Joan N; Schroeder, T V

    1994-01-01

    Popliteal artery entrapment syndrome (PAES) should be suspected in young persons without predisposing factors to arteriosclerosis, who present with unilateral claudication in the calf and foot. This entity results from a developmental abnormal relation between the popliteal artery and the medial...... head of the gastrocnemius muscle. PAES is mostly found in young sportsmen or young soldiers with well-developed muscles. The onset of the symptoms is often sudden, occurring during an episode of intense lower extremity activity. The diagnosis is best established by a thorough clinical examination...

  4. Single umbilical artery in fetopathological investigations.

    Science.gov (United States)

    Joó, József Gábor; Beke, Artúr; Papp, Zoltán; Rigó, János; Papp, Csaba

    2008-01-01

    Single umbilical artery (SUA) is a relatively common malformation that may call attention to the possibility of associated malformations (often chromosome aberrations). The current study aimed at surveying malformations associated with SUA on the basis of fetopathological investigations, analyzing the role of history, summarizing the clinically important factors emerging together with this malformation. In this study, we processed the details of 204 cases in which SUA was confirmed fetopathologically after miscarriage or induced abortion between 1990 and 2007. In our sample, SUA occurred in 7.38% of the cases. The history was positive in almost 30% of the cases. The majority of the cases had a positive obstetric and the minority of them a positive genetic history. The highest association of SUA with other malformations was found for craniospinal ones, but an association with cardiovascular malformations should also be mentioned. Regarding the individual types of malformation, SUA was most commonly associated with hydrocephalus, but Potter's sequence, trisomy 21, and atrioventricular septal defect also reached a higher rate in associated SUA. Previously published articles dealing with associated malformations found that urogenital malformations were most commonly associated with SUA. 'Itemizing' the different non-chromosomal malformations in association with SUA, we found that hydrocephalus, Potter's sequence, and atrioventricular septal defect were the most frequent malformations, while in earlier studies, the association with non-chromosomal malformations such as vertebral malformations, imperforated anus, cheilognathopalatoschisis, and renal agenesis occurred more frequently than usual.

  5. Umbilical cord blood mercury levels in China

    Institute of Scientific and Technical Information of China (English)

    Meiqin Wu,; Chonghuai Yan; Jian Xu; Wei Wu; Hui Li; Xin Zhou

    2013-01-01

    Mercury (Hg) is a well-known neurotoxicant.Hg exposure at high levels can harm individuals of all ages.Even low level exposure to Hg can damage the brain of fetuses and young children,and affect their central nervous system and cognitive development.The aims of our study were to measure total Hg levels in infant umbilical cord blood and to investigate the risk factors associated with total Hg cord blood levels in various cities in China.Our goal was to provide clues for the prevention of Hg exposure in utero.The results indicated that the average cord blood mercury levels (CBMLs) were (1.81 ± 1.93) μg/L,which were lower than those found in most previous studies.The concentrations also differed according to geographic region.The CBMLs were not only associated with family economic and living conditions,but also with diet in pregnant women,especially the intake of marine fish,shellfish,poultry,formula milk and fruits.

  6. Estudo ultra-sonográfico da involução uterina pós-parto em cadelas Ultrasonography study of the post-partum uterine involution in bitches

    Directory of Open Access Journals (Sweden)

    S.T.S. Ferri

    2002-02-01

    Full Text Available Utilizando-se 15 cadelas no pós-parto, são descritas as características da involução uterina e determinado o diâmetro do útero, por meio de exames seriados de ultra-som em modo B (tempo real, no período de zero a 28 dias pós-parto. O diâmetro uterino declina progressivamente, sem influência da ordem de parto ou tamanho da ninhada. As características ultra-sonográficas do útero são melhor visualizadas na primeira semana pós-parto e a qualidade da imagem diminui com o progresso da involução. Pela técnica usada são visualizadas apenas três camadas constituintes da parede uterina.The ultrasonographic characteristics and the involution of the uterus were described in 15 pregnant bitches by serial B-mode (real time technique at period of 0 to 28 days postpartum. The uterine diameter decreased progressively, without influence of parity or litter size. The ultrasonographic image of the uterus is better view in the first week and the image quality is poor at subsequent weeks. The uterus was composed of only three ecographic layers.

  7. PAPEL DE LA MEDICIÓN DE LA VELOCIDAD SISTÓLICA MÁXIMA EN ARTERIA CEREBRAL MEDIA EN LA ISOINMUNIZACIÓN RHESUS

    OpenAIRE

    2010-01-01

    Objetivo: Evaluación del papel de la velocidad sistólica máxima en arteria cerebral media (VSM-ACM) en casos de isoinmunización Rh. Métodos: 67 casos de isoinmunización Rh, en el Hospital La Paz desde febrero del 2006 hasta agosto del 2009, con título de anticuerpos > 1:32, afectación en embarazo previo y/o casos de isoinmunización anti- Kell, en los que se ha realizado medición de la VSM-ACM. Resultados: La capacidad de detección de anemia moderada-severa en base a la medición de VSM-ACM pre...

  8. Hacer arteria carótida en el Laboratorio de Anatomía. Práctica y materialidad en una asignatura de Medicina

    Directory of Open Access Journals (Sweden)

    Santiago Martínez Medina

    2016-07-01

    Full Text Available Este artículo parte de la siguiente pregunta: ¿Cómo se hace un cuerpo en la asignatura de Anatomía? Me interesa el cuerpo como materialidad, experiencia y producto de una práctica bastante específica, de la cual surge como un ente natural y trascendente. Para referirme a la práctica de hacer un cuerpo, hago un análisis etnográfico de la asignatura en conjunto: observo los estudiantes, los profesores, los libros, las pinzas, las manos y los cadáveres usados. Este análisis es producto de mi participación durante más de un año en las clases y en los laboratorios de la asignatura de Anatomía, en dos facultades de Medicina, en la ciudad de Bogotá, Colombia. Se trata de una etnografía de una serie de movimientos corporales específicos, con los cuales se aprende a hacer anatomía humana, con un amplio rango de materialidades (cadáveres, libros, dispositivos virtuales, modelos tridimensionales, etcétera. Gracias a mi participación en este espacio de enseñanza, elaboré un diario de campo que luego transcribí, para someterlo a un análisis. En este, me interesa dar cuenta de aquellos momentos en los que una estructura anatómica es producto de las prácticas de la asignatura. Así, este artículo explora, en específico, la manera en que se hacen arterias en el anfiteatro de Anatomía. Mi pregunta no es cómo se identifican determinados vasos sanguíneos en el cuerpo humano, sino cómo se configuran sus distintas propiedades y particularidades en el laboratorio, incluido un nombre que los identifica. La cuestión no es, pues, epistemológica sino ontológica. De esta manera, en este artículo muestro que en el laboratorio surgen sensaciones y trayectorias materiales como si fueran arterias específicas. Para esto, se requiere de un espacio orientado y de la participación de múltiples entidades, heterogéneas y parcialmente conectadas, que enriquecen la experiencia de hacer una arteria en el laboratorio. As

  9. Embolización de la arteria esplénica como tratamiento del hiperesplenismo en pacientes hemofílicos, HIV-1 y HCV seropositivos

    Directory of Open Access Journals (Sweden)

    M. E. Corti

    2003-06-01

    Full Text Available La trombocitopenia es una anomalía usual e importante en pacientes con coinfección por HIV-1/HCV. La esplenomegalia es un hallazgo frecuente en estos pacientes y, usualmente, causa hiperesplenismo y trombocitopenia. Analizamos los resultados clínicos de un método invasivo mínimo (embolización de la arteria esplénica para el tratamiento de la trombocitopenia secundaria al hiperesplenismo y refractaria a otras terapias en dos pacientes hemofílicos, infectados por el HIV-1 y con cirrosis causada por la infección crónica por HCV. Estos resultados sugieren que la embolización de la arteria esplénica es un método seguro, poco traumático y efectivo para el tratamiento de la esplenomegalia y el hiperesplenismo en pacientes con coinfección por HIV-1/HCV.Thrombocytopenia is an important and common hematological abnormality in patients with HIV-1/HCV coinfection. Splenomegaly is a frequent finding in these patients and usually causes hypersplenism and thrombocytopenia. We analyzed the clinical results of a minimal invasive treatment (splenic artery embolization for thrombocytopenia secondary to hypersplenism and refractory to other therapies in two hemophiliac patients, HIV seropositive and with cirrhosis due to chronic HCV infection. The results suggest that splenic artery embolization is a safe, relatively atraumatic and effective method for the treatment of splenomegaly and hypersplenism in selected patients with HIV-1/HCV coinfection.

  10. Validación del Protocolo para el Estudio de la Hemorragia Uterina Anormal con Ecografía endovaginal y medio de Contraste (Sonohisterografía.

    Directory of Open Access Journals (Sweden)

    Ricardo Rueda Saenz

    2003-08-01

    Full Text Available

    La evaluación del sangrado uterino anormal (SUA especialmente en los años postreproductivos, convencionalmente se hace recurriendo a las biopsias y aspiraciones endometriales ciegas en el consultorio, o al curetaje uterino bajo anestesia general. Dichos procedimientos, además de ser invasivos, han mostrado ser poco sensibles y específicos en la detección y el tratamiento de la patología focal del endometrio (pólipos, leiomiomas submucosos, y además pueden resultar costosos. Con el advenimiento de la histeroscopia, se han obviado muchas de las dificultades atribuidas a la biopsia ciega y el curetaje uterino, pero aquella, además de requerir un entrenamiento específico y un equipo costoso, requiere de anestesia local o general, en ocasiones dilatación del cervix y en muchas instancias arroja resultados negativos.

    De otro lado, la histeroscopia sólo permite evaluar el canal cervical y la cavidad endometrial, sin poder visualizar la pared miometrial, los anexos y otras estructuras pélvicas, lo cual desvirtúa su uso en una gran proporción de pacientes como investigación inicial rutinaria en el sangrado uterino anormal.

    La utilización de la ecografía transvaginal con contraste líquido (sonohisterografía o histerosonografía permite, por el contrario, no solamente una evaluación precisa y detallada del canal cervical y la cavidad endometrial, sino que permite evaluar la pared miometrial, los ovarios y otras estructuras pélvicas, así como la permeabilidad de las trompas uterinas.

    Este procedimiento tiene además un bajo costo, no requiere de entrenamiento especial, tampoco de anestesia ni de dilatación cervical y tiene bajas tasas de complicaciones. Con la sonohisterografía se pueden seleccionar en forma eficiente y rápida, las mujeres que realmente se benefician de una histeroscopia diagnóstica-operatoria o de una biopsia endometrial ciega de consultorio para evaluar el SUA.

    El presente estudio

  11. Papilomavírus humano associado a lesões de cérvice uterina Human papillomavirus associated to uterine cervix lesions

    Directory of Open Access Journals (Sweden)

    Vânia Noronha

    1999-06-01

    Full Text Available Estudou-se a prevalência do papilomavírus humano (HPV em 228 mulheres portadoras de lesões em cérvice uterina, atendidas no Instituto Ofir Loiola, em Belém, Pará, no período de março de 1992 a maio de 1996. As pacientes foram submetidas à biópsia de colo uterino, sendo o material encaminhado para histopatologia e pesquisa de HPV por PCR e hibridização por dot-blot. Distribuíram-se as participantes em três grupos, conforme diagnóstico histopatológico. O grupo A constituiu-se de 155 mulheres com carcinoma epidermóide invasor ou com adenocarcinoma, o grupo B de 54 portadoras de neoplasia intra-epitelial cervical grau II ou III, e o grupo C de 19 pacientes com cervicite crônica. Observaram-se prevalências de HPV em 70,3%, 63,0% e 36,8% das mulheres dos grupamentos A, B e C, respectivamente, sendo o HPV 16 registrado em 60,4% das amostras positivas do grupo A e 54,5% daquelas do grupo B. Os tipos 16, 18 e 33 representaram 71,4% dos detectados no grupo C.It was studied the prevalence of human papillomavirus (HPV among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In addition, specimens were analysed by both polimerase chain reaction and dot-blot hybridization to detect HPV DNA. The patients were assigned to three groups, according to the diagnosis made by histopathology, as follows: A, including 155 women suffering from invasive epidermoid carcinoma or adenocarcinoma; B, 54 patients having either cervical intraepithelial neoplasia grade II or III; and C, involving 19 women with chronic cervicitis. The prevalence rates of HPV in groups A, B and C were 70.3%, 63% and 36.8% respectively. HPV 16 accounted for 60.4% and 54.5% of types identified in groups A and B, respectively. Altogether HPV types 16, 18 and 33 were detected in 71.4% of positive patients

  12. [Umbilical artery blood gases of term neonates at altitude].

    Science.gov (United States)

    Villamonte, Wilfredo; Escalante, Darío; Yabar, Janet; Jerí, María; Peralta, Paola; Ochoa, Robert

    2014-01-01

    In order to determine the normal values of arterial blood gases in the umbilical artery of term infants at 3400 m altitude, a cross-sectional study was conducted. It was performed in the umbilical artery blood of 300 term infants, with an adequate gestational age and whose birth took place between January 2010 and December 2011 at the Essalud National Hospital Adolfo Guevara Velazco (Cusco, Peru). It was found that the average pH of healthy term infants was 7.33 ± 0.07; the values for percentiles 5 and 95 were 7.18 and 7.40 respectively. Tables with the 5th and 95th percentiles for pH, pO2, pCO2, SO2, p50, base excess and HCO3 of the umbilical artery of term infants at 3400 m altitude are provided.

  13. Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy

    Directory of Open Access Journals (Sweden)

    Soner Sazak

    2012-01-01

    Full Text Available Objective. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin. Methods. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33% smoking and 40 (67% nonsmoking mothers. Results. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 ± 9 IU/L; smokers, 61 ± 46 IU/L; P<.001. There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (r, 0.58; P≤.05. Conclusions. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality.

  14. Frequência de mola hidatiforme em tecidos obtidos por curetagem uterina Frequency of hydatidiform mole in tissue obtained by curettage

    Directory of Open Access Journals (Sweden)

    Andressa Biscaro

    2012-06-01

    Full Text Available OBJETIVO: Determinar a frequência de mola hidatiforme em tecidos obtidos por curetagem uterina. MÉTODOS: Estudo transversal, prospectivo e descritivo que incluiu pacientes submetidas à curetagem uterina por diagnóstico de aborto ou mola hidatiforme cujo material obtido foi encaminhado para exame anatomopatológico. Foram excluídas aquelas que não aceitaram participar da pesquisa, recusando-se a assinar o Termo de Consentimento Informado Livre e Esclarecido. Foram analisadas as seguintes variáveis: achados anatomopatológicos, idade, raça/cor, número de gestações e abortos prévios, idade gestacional no momento do diagnóstico, níveis séricos quantitativos da fração beta da gonadotrofina coriônica humana e achados ultrassonográficos. As variáveis foram empregadas para a verificação com o diagnóstico histológico, considerado o padrão-ouro. Os dados foram armazenados e analisados no software Microsoft Excel® e no programa Epi-Info, versão 6.0 (STATCALC e os resultados apresentados como frequência (porcentagem ou média±desvio padrão. Para a associação entre variáveis qualitativas foi usado o teste do χ², e admitiu-se significância estatística quando pPURPOSE: To determine the frequency of hydatiform mole in tissues obtained by curettage. METHODS: A cross-sectional, prospective and descriptive conducted on patients who underwent curretage due to a diagnosis of abortion or hydatiform mole whose material was sent for pathological examination. We excluded women who did not accept to participate and refused to sign the free informed consent form. We studied the following variables: pathological findings, age, race, number of pregnancies and previous abortions, gestational age at diagnosis, quantitative serum beta fraction of human chorionic gonadotropin and ultrasound findings. The data were compared to the to histological diagnosis, considered to be the gold standard. Data were stored and analyzed in Microsoft Excel

  15. Acute Abdomen Secondary to Incarcerated Umbilical Hernia after Treatment of Massive Cirrhotic Ascites

    Directory of Open Access Journals (Sweden)

    Hiang Keat Tan

    2013-01-01

    Full Text Available Umbilical herniation is common in patients with liver cirrhosis and ascites. Rarely, they suffer from incarceration and strangulation of the umbilical hernia after treatment of ascites. We report 3 cases of umbilical hernia incarceration following removal of massive ascites with different treatment modalities. Physicians managing this group of patients should be aware of this rare and potentially fatal complication.

  16. Acute Abdomen Secondary to Incarcerated Umbilical Hernia after Treatment of Massive Cirrhotic Ascites

    OpenAIRE

    2013-01-01

    Umbilical herniation is common in patients with liver cirrhosis and ascites. Rarely, they suffer from incarceration and strangulation of the umbilical hernia after treatment of ascites. We report 3 cases of umbilical hernia incarceration following removal of massive ascites with different treatment modalities. Physicians managing this group of patients should be aware of this rare and potentially fatal complication.

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  20. Isolation and culture of human umbilical vein endothelial cells (HUVEC).

    Science.gov (United States)

    Cheung, Ambrose L

    2007-02-01

    Human-derived endothelial cells can now be routinely harvested from human umbilical veins. Studies with human umbilical vein endothelial cells (HUVEC) have been conducted with cells from passage 2 to 5. It is now also possible to cryopreserve primary and early-passaged HUVEC for future propagation and for forwarding to an end user by express courier. Stored HUVEC have been stably retrieved even after several years. These retrieval techniques have facilitated the deployment of HUVEC for many studies, including those for homeostasis, inflammatory disorders, atherosclerosis, cancer, and microbial adhesion and invasion. In this unit, we will delineate the procedure for harvesting, propagation, and storage of HUVEC.

  1. Dielectric properties of human placenta, umbilical cord and amniotic fluid

    Energy Technology Data Exchange (ETDEWEB)

    Peyman, A [Physical Dosimetry Department, Health Protection Agency, Chilton, Didcot OX11 0RQ (United Kingdom); Gabriel, C [MCL-P, Newbury RG14 5PY, Berkshire (United Kingdom); Benedickter, H R; Froehlich, J, E-mail: Azadeh.peyman@hpa.org.uk [Electromagnetic Fields and Microwave Electronics Laboratory, Swiss Federal Institute of Technology, Zurich (Switzerland)

    2011-04-07

    The dielectric properties of freshly delivered human placenta, umbilical cord and amniotic fluid have been acquired at 37 deg. C and in the frequency range of 200 MHz-10 GHz. The experimental data were fitted to a Cole-Cole expression. The results show that dielectric properties of the umbilical cord are significantly higher than placenta due to the presence of high water content Wharton's jelly. The results also demonstrate large differences in the dielectric properties of amniotic and cerebrospinal fluids. The data presented can be used in numerical simulations of the exposure of pregnant women to electromagnetic fields. (note)

  2. Dielectric properties of human placenta, umbilical cord and amniotic fluid

    Science.gov (United States)

    Peyman, A.; Gabriel, C.; Benedickter, H. R.; Fröhlich, J.

    2011-04-01

    The dielectric properties of freshly delivered human placenta, umbilical cord and amniotic fluid have been acquired at 37 °C and in the frequency range of 200 MHz-10 GHz. The experimental data were fitted to a Cole-Cole expression. The results show that dielectric properties of the umbilical cord are significantly higher than placenta due to the presence of high water content Wharton's jelly. The results also demonstrate large differences in the dielectric properties of amniotic and cerebrospinal fluids. The data presented can be used in numerical simulations of the exposure of pregnant women to electromagnetic fields.

  3. Embolização uterina para tratamento de miomas sintomáticos: impacto na qualidade de vida Uterine embolization for management of symptomatic fibroids: quality-of-life impact

    Directory of Open Access Journals (Sweden)

    Nestor Kisilevzky

    2007-10-01

    Full Text Available OBJETIVO: Verificar a mudança na qualidade de vida de pacientes portadoras de miomatose uterina sintomática submetidas a tratamento por embolização. MATERIAIS E MÉTODOS: Quarenta mulheres portadoras de miomatose uterina sintomática que foram tratadas com a técnica de embolização responderam a um questionário de qualidade de vida antes e 12 semanas após o procedimento. RESULTADOS: Verificou-se que o escore médio relacionado com a gravidade dos sintomas nas 40 pacientes antes da embolização foi de 62,07 ± 6,34 e se modificou, com significância estatística após o tratamento, quando se verificou escore médio de 20,42 ± 3,81. Da mesma forma, comprovou-se a melhora na qualidade de vida pela modificação dos escores antes e depois do tratamento, o que também apresentou significância estatística, passando de 40,26 ± 2,98 para 85,06 ± 2,57. CONCLUSÃO: A embolização uterina provoca alívio evidente dos sintomas relacionados com a miomatose e proporciona melhora substancial da qualidade de vida das pacientes.OBJECTIVE: To determine the impact on the quality of life in patients with symptomatic uterine fibroids submitted to uterine artery embolization. MATERIALS AND METHODS: Forty patients with symptomatic fibroids submitted to embolization have answered a quality-of-life questionnaire before and 12 weeks after the procedure. RESULTS: Mean score for symptoms severity before the procedure was 62.07 ± 6.34 and decreased with statistical significance to 20.42 ± 3.81 after the procedure. Similarly, scores for quality of life have improved from 40.26 ± 2.98 before the procedure to 85.06 ± 2.57 after the procedure, which again was statistically significant. CONCLUSION: Uterine embolization results in evident symptoms relief and significant improvement in the quality of life of patients with symptomatic fibroids.

  4. Disección traumática de la arteria carótida interna y embolismo cerebral en un jugador de fútbol. Reporte del primer caso.

    OpenAIRE

    Talledo Paredes, Luisa; Médico Residente de Cardiología. Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia.Lima.; Rotta Rotta, Aida; Médico Asistente. Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Profesor Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia.Lima; Dueñas Carbajal, Roy; Médico Asistente. Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Profesor Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia.Lima.; Medina Palomino, Félix; Médico Asistente. Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Profesor Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia.Lima.; Anchante Hernández, Henry; Médico Asistente. Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Profesor Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia.Lima.; Salazar Cáceres, Pedro; Jefe del Servicio de Cardiología, Hospital Nacional Cayetano Heredia. Lima.

    2012-01-01

    Reportamos el caso de un varón de 18 años quien sufrió contusión cervical por impacto con balón de fútbol. Tres días después fue hospitalizado con  hemiplejia derecha directa y afasia de expresión. La resonancia magnética cerebral mostró lesión isquémica izquierda en ganglios basales. El doppler carotideo evidenció trombo desde el origen de la arteria carótida común izquierda extendida a la arteria carótida interna izquierda (CII) y la angiotomografía documentó disección de CII (lesión traumá...

  5. Relationship between newborn Acid-Base status and umbilical cord morphology

    Directory of Open Access Journals (Sweden)

    Marssosi V

    2001-06-01

    Full Text Available ess the relationship between umbilical cord blood gases at birth and morphology of umbilical cord, in a prospective study of 200 consecutive term delivery, we investigated the relationship between umbilical cord morphology characteristics (umbilical crd length, number of vascular coil, coiling index and color of amniotic fluid and umbilical vessel blood gases. Statistically significant linear correlation was found between umblicial venous PH and the umbilical cord length (r=0.39, 95% CI 0.25, 0.53, P<0.03, umber of vascular coils (r=0.45 95% CI 0.31-0.59 P<0.012, and coiling index (r=0.34, 95% CI 0.12-0.48, P<0.04, and also negative linear correlation was found between umbilical venous partial pressure of carbon dioxide & of coli (r=0.3, 95% CI –0.44, -0.16 P<0.03. No relation was found between umbilical cord indices and meconium staining of amniotic fluid.Placental weight also correlated with umbilical cord length (r=0.17, 95% CI 0.03-0.31, P<0.03, but not with umbilical cord coils or coiling index.Umbilical venous pH is related to umbilical cord morphology but umbilical venous PCO2 was only related to the number of coils and umbilicat artery pH wa only related to the number of coils and not related to length or coiling index of umbilical cord morphology. The morphology of umbilical cord can affect maternal-fetal gas exchange

  6. Determinación de las características anatómicas de las arterias coronarias de cerdo mediante técnica de inyección con látex

    Directory of Open Access Journals (Sweden)

    Guillermo Rivera

    2015-06-01

    Full Text Available Objetivo: Determinar las características anatómicas de las arterias coronarias del cerdo, mediante inyección con látex. Materiales y métodos: Se usaron 100 corazones de cerdo. Se insertaron sondas Nelaton a través de las arterias coronarias y se les inyectó solución de látex y tinta china. Se determinó el diámetro y el punto de origen para la coronaria derecha, coronaria izquierda, interventricular paraconal y circunfleja. Se cuantificaron el número de ramas diagonales, marginales ventriculares izquierdas y postero laterales. Se determinó frecuencia de ramus intermedius y tipo de dominancia. Se realizó análisis estadístico con un error estándar del 5%, con el Epidat 3,1. Resultados: El 100% de los orígenes anatómicos de las arterias coronarias fueron normales. La dominancia mas frecuente fue la derecha, 73%. El promedio de número de ramas marginales izquierdas, diagonales y posterolaterales fue de 3. La frecuencia de ramus intermedius fue de 12%. El calculo de chi cuadrado de Pearson mostró significancia entre el ramus intermedius y número de ramas marginales izquierdas (p=0,0009. Conclusiones: Las características anatómicas de las arterias coronarias del cerdo son similares a las del humano. El ramus intermedius se comporta como una primera rama marginal izquierda y no como una primera rama diagonal como lo afirman algunos autores.

  7. Tratamiento de la compresión del tronco de la arteria coronaria izquierda en pacientes con hipertensión pulmonar Treatment of compression of the left main coronary artery in patients with pulmonary hypertension

    Directory of Open Access Journals (Sweden)

    María L. Talavera

    2011-10-01

    Full Text Available La angina de pecho es un síntoma frecuente en pacientes con hipertensión pulmonar (HP de cualquier etiología. Aunque su fisiopatología no está aclarada, las causas propuestas son: la isquemia subendocárdica por aumento del estrés parietal del ventrículo derecho, la dilatación de la arteria pulmonar por incrementos transitorios de la presión pulmonar y la compresión extrínseca del tronco de la arteria coronaria izquierda (TCI por la arteria pulmonar (AP dilatada. Se presentan tres casos que muestran la relación entre la angina de pecho y la compresión del TCI en pacientes con HP asociada a cardiopatías congénitas, tratados mediante implante de stent coronario.Chest pain is a frequent symptom in patients with pulmonary hypertension of any etiology. Its pathophysiology has not been clearly established, the proposed causes are ischemia due to increased right ventricle wall stress, transient increased pulmonary hypertension resulting in acute pulmonary artery dilatation and external compression of the left main coronary artery (LMCA by a dilated pulmonary artery. We report and discuss here three cases where the association between chest pain and compression of the LMCA by a dilated pulmonary artery could be shown, and they were treated with coronary stenting.

  8. Umbilical hernia in patients with liver cirrhosis: A surgical challenge

    Institute of Scientific and Technical Information of China (English)

    Julio CU Coelho; Christiano MP Claus; Antonio CL Campos; Marco AR Costa; Caroline Blum

    2016-01-01

    Umbilical hernia occurs in 20% of the patients with liver cirrhosis complicated with ascites. Due to the enormous intraabdominal pressure secondary to the ascites, umbilical hernia in these patients has a tendency to enlarge rapidly and to complicate. The treatment of umbilical hernia in these patients is a surgical challenge. Ascites control is the mainstay to reduce hernia recurrence and postoperative complications, such as wound infection, evisceration, ascites drainage, and peritonitis. Intermittent paracentesis, temporary peritoneal dialysis catheter or transjugular intrahepatic portosystemic shunt may be necessary to control ascites. Hernia repair is indicated in patients in whom medical treatment is effective in controlling ascites. Patients who have a good perspective to be transplanted within 3-6 mo, herniorrhaphy should be performed during transplantation. Hernia repair with mesh is associated with lower recurrence rate, but with higher surgical site infection when compared to hernia correction with conventional fascial suture. There is no consensus on the best abdominal wall layer in which the mesh should be placed: Onlay, sublay, or underlay. Many studies have demonstrated several advantages of the laparoscopic umbilical herniorrhaphy in cirrhotic patients compared with open surgical treatment.

  9. Umbilical hernia in cirrhotic patients: outcome of elective repair.

    Science.gov (United States)

    Lasheen, Adel; Naser, Hatem M; Abohassan, Ahmed

    2013-12-01

    Cirrhotic patients with umbilical hernia have an increased likelihood of complications following repair. The aim of this study was to assess the outcomes of elective umbilical hernia repair in cirrhotic patients. Fifty patients having uncomplicated umbilical hernia with a cirrhotic liver were studied prospectively. These patients divided into three groups' according to Child-Turcotte-Pugh (CTP) classification. After management of coagulopathy, correction of hypoalbuminaemia and electrolytes imbalance, and control of ascites, all patients underwent elective hernia repair under regional anesthesia. A comparison was made between the three groups as regard the size of the defect in the linea Alba, operative time, postoperative morbidity and mortality, length of hospital stay, time of return to daily life and postoperative changes in liver function tests (LFTs) in relation to the regional anesthesia applied. hernioplasty was done under spinal anesthesia in 13 patients (26%), under epidural anesthesia in 10 patients (20%), under intercostal nerve block in 7 patients (14%), and under local anesthesia in 20 patients (40%). There was an increased safety (less changes in LFTs) in cases done under local anesthesia and intercostal nerve block. The overall complications rate was 30%. There was an increased complications rate towards the decompensated cases. The differences in the mean length of hospital stay and mean time of return to daily life are statistically significant between the three groups. Umbilical hernia recurrence rate was 2% and no mortality was reported in the study groups.

  10. Outcome of surgical treatment for umbilical swellings in bovine youngstock.

    Science.gov (United States)

    Williams, H J; Gillespie, A V; Oultram, J W; Cripps, P J; Holman, A N

    2014-03-01

    Umbilical swellings are commonly identified in calves and can be caused by hernia formation, infection of the remnants of umbilical vessels or a combination of both. Ninety-one cases with umbilical swellings were admitted to the Leahurst Farm Animal Practice (LFAP) between July 2004 and February 2012; 55 were simple hernias and 36 had associated infection. Eighty-seven cases underwent surgery of which 86 survived until discharge. Postoperative complications occurred in 65/86 animals (73 per cent). In 51 cases (81 per cent) this was classified as minor requiring no additional treatment. Placement of a prosthetic mesh was associated with a higher OR for developing severe postoperative complication when compared with those not receiving a mesh (OR=19.3; 95% CI 4.5 to 83.5). Long-term survival results were available for 49 animals, 22 of which were remaining in the herd with a median age of 1346 days (3.7 years). Of the 27 animals which had exited the herd, 16 were adult dairy cows, 7 were dairy heifers, 2 were beef animals and 2 exited at an unknown stage. Umbilical surgery in calves carries a good prognosis, although placement of a mesh increases the risk of complications occurring in the postoperative period.

  11. Umbilical hernia in patients with liver cirrhosis: A surgical challenge.

    Science.gov (United States)

    Coelho, Julio C U; Claus, Christiano M P; Campos, Antonio C L; Costa, Marco A R; Blum, Caroline

    2016-07-27

    Umbilical hernia occurs in 20% of the patients with liver cirrhosis complicated with ascites. Due to the enormous intraabdominal pressure secondary to the ascites, umbilical hernia in these patients has a tendency to enlarge rapidly and to complicate. The treatment of umbilical hernia in these patients is a surgical challenge. Ascites control is the mainstay to reduce hernia recurrence and postoperative complications, such as wound infection, evisceration, ascites drainage, and peritonitis. Intermittent paracentesis, temporary peritoneal dialysis catheter or transjugular intrahepatic portosystemic shunt may be necessary to control ascites. Hernia repair is indicated in patients in whom medical treatment is effective in controlling ascites. Patients who have a good perspective to be transplanted within 3-6 mo, herniorrhaphy should be performed during transplantation. Hernia repair with mesh is associated with lower recurrence rate, but with higher surgical site infection when compared to hernia correction with conventional fascial suture. There is no consensus on the best abdominal wall layer in which the mesh should be placed: Onlay, sublay, or underlay. Many studies have demonstrated several advantages of the laparoscopic umbilical herniorrhaphy in cirrhotic patients compared with open surgical treatment.

  12. Hydrogen Vent Ground Umbilical Quick Disconnect - Flight Seal Advanced Development

    Science.gov (United States)

    Girard, Doug; Jankowski, Fred; Minich, Mark C.; Yu, Weiping

    2012-01-01

    This project is a team effort between NASA Engineering (NE) and Team QNA Engineering personnel to provide support for the Umbilical Systems Development project which is funded by Advanced Exploration Systems (AES) and 21st Century Launch Complex. Specifically, this project seeks to develop a new interface between the PPBE baselined Legacy SSP LH2 Vent Arm QD probe and SLS vent seal.

  13. Estimation of the total number of mast cells in the human umbilical cord. A methodological study

    DEFF Research Database (Denmark)

    Engberg Damsgaard, T M; Windelborg Nielsen, B; Sørensen, Flemming Brandt

    1992-01-01

    disector and fractionated sampling. The mast cell of the human umbilical cord was found in Wharton's jelly, most frequently in close proximity to the three blood vessels. No consistent pattern of variation in mast cell numbers from the fetal end of the umbilical cord towards the placenta was seen......The aim of the present study was to estimate the total number of mast cells in the human umbilical cord. Using 50 microns-thick paraffin sections, made from a systematic random sample of umbilical cord, the total number of mast cells per cord was estimated using a combination of the optical....... The total number of mast cells found in the umbilical cord was 5,200,000 (median), range 2,800,000-16,800,000 (n = 7), that is 156,000 mast cells per gram umbilical cord (median), range 48,000-267,000. Thus, the umbilical cord constitutes an adequate source of mast cells for further investigation...

  14. Papel da Histerossonografia no Estudo da Cavidade Uterina em Pacientes com Sangramento Uterino Anormal Role of Sonohysterography in the Evaluation of the Uterine Cavity in Patients with Abnormal Uterine Bleeding

    Directory of Open Access Journals (Sweden)

    Angélica Lemos Debs Diniz

    2000-06-01

    Full Text Available Objetivo: determinar o papel da histerossonografia na avaliação das anormalidades da cavidade uterina, em pacientes com sangramento uterino anormal, selecionadas previamente pela ultra-sonografia transvaginal. Métodos: foram selecionadas 48 pacientes na menacme e pós-menopausa, portadoras de sangramento uterino anormal e anormalidades da cavidade uterina, diagnosticadas inicialmente pela ultra-sonografia transvaginal. Todas as pacientes se submeteram à histerossonografia e, posteriormente, aos métodos "padrão ouro", a histeroscopia e/ou histerectomia. As histerossonografias foram avaliadas por dois diferentes médicos e os diagnósticos confrontados. Resultados: a histerossonografia mostrou ter alta sensibilidade e especificidade no diagnóstico das patologias benignas da cavidade uterina. Na presença de pólipo a sensibilidade e a especificidade do método foram, respectivamente, de 100 e 97%, seguido do mioma submucoso cuja sensibilidade e especificidade foram, respectivamente, de 83 e 100%. Já na hiperplasia endometrial e no endométrio normal a sensibilidade e especificidade foram de 100%. Diagnosticamos 33 casos de pólipos, 13 casos de miomas submucosos, quatro casos de hiperplasia endometrial e três casos normais na análise dos métodos "padrão ouro". Houve alta correlação entre os diagnósticos dados pelos dois examinadores. Conclusões: a histerossonografia mostrou ser um exame reprodutível, com alta sensibilidade e especificidade no diagnóstico das patologias benignas da cavidade uterina em pacientes com sangramento uterino anormal.Purpose: to determine the role of sonohysterography in the evaluation of abnormalities in the uterine cavity in patients presenting abnormal uterine bleeding, who had previously been selected by transvaginal ultrasonography. Methods: forty-eight patients presenting abnormal uterine bleeding and changes in the uterine cavity seen by transvaginal ultrasonography were selected, and they were in

  15. Evaluation of a second uterine flushing on embryo recovery in Nelore cows / Avaliação de uma segunda lavagem uterina sobre a recuperacão de embriões em vacas Nelore

    Directory of Open Access Journals (Sweden)

    Marcelo Marcondes Seneda

    2008-08-01

    Full Text Available The objective of the present study was to evaluate the effect of a second uterine flushing on number of recovered embryos. Cyclic Nelore cows (n= were used as donors. Animals were kept under grazing conditions in a farm at Mamborê, Paraná state. Cows were submitted to two sessions of multiple ovulation 80 days apart. At a random stage of estrus cycle (Day 0 donors received an intravaginal device with 1.9 g of progesterone (CIDR; Pfizer; Brasil. Twenty four hours later (Day 1 cows were injected with 2.5 mg/ IM of Estradiol Benzoate (Estrogin, Farmavet, Brasil. Between Day 5 and Day 9, donors received decreasing doses of 250 UI of FSH (Pluset; Calier, Brasil. On Days 7 and cows received 25 mg/ IM of dinoprost (Lutalyse, Pfizer, Brasil and progesterone implants were removed 12 hs later. Artificial insemination was performed 12 and 24 hours after estrus detection. The first embryo recovery was performed 7 days after AI with the Foley catheter positioned in the uterine body. A total of 1.000 mL of PBS (Embriocare, Cultilab, Brasil was used in a closed system of uterine flushing, with a 70 µm filter. Recovered uterine fluid was evaluated under a stereomicroscope (SMZ 654, Nikon, Japan and embryos were classified accord to IETS (1998. Twenty four hours later, the second uterine flushing was performed following the same procedure. Results were analyzed by t-Student test (p O objetivo do presente experimento foi verificar a viabilidade de uma segunda lavagem uterina sobre a recuperação de embriões. Doadoras cíclicas da raça Nelore (n= foram mantidas a pasto no município de Mamborê, Estado do Paraná. Os animais foram submetidos a tratamentos de superovulação com intervalo de 80 dias. Em um dia aleatório do ciclo estral (Dia 0 as doadoras receberam um dispositivo intravaginal contendo 1,9 g de progesterona (CIDR; Pfizer, Brasil. Vinte e quatro horas após (Dia 1 administrou-se , mg de benzoato de Estradiol (Estrogin; Farmavet, Brasil por via

  16. Prevenção do Nascimento Prematuro: Importância da Monitorização das Contrações Uterinas Prevention of Preterm Birth: Role of Uterine Contraction Monitoring

    Directory of Open Access Journals (Sweden)

    Eduardo Sérgio Borges da Fonseca

    1999-10-01

    Full Text Available Objetivo: avaliar a relação entre alterações das contrações uterinas e parto prematuro. Metodologia: entre fevereiro de 1996 e junho de 1998, 73 gestantes com risco para o parto prematuro foram submetidas à monitorização externa das contrações uterinas, da 24ª à 34ª semana de gestação, duas vezes por semana, durante 60 minutos. O teste foi considerado positivo quando as contrações uterinas apresentavam freqüência maior ou igual a 4 contrações/hora antes da 30ª semana e a 6 contrações/hora após esta data. Resultado: foram excluídas da análise 17 pacientes (23,28% por apresentarem patologias obstétricas ou evolução desfavorável para os resultados finais. Das 56 gestantes restantes, a incidência de partos prematuros espontâneos foi de 23,21% (13/56. A freqüência média das contrações uterinas foi significativamente maior no grupo que evoluiu para o parto prematuro. O método revelou uma sensibilidade de 69,23%, uma especificidade de 86,04% e valores preditivos positivo e negativo de 60% e 90,24%, respectivamente. Conclusão: o teste negativo está associado a baixo risco de nascimento prematuro. Contudo, diante do teste positivo, torna-se necessária a associação com outros marcadores do parto prematuro para melhor identificar pacientes com risco elevado.Purpose: to evaluate the relationship between uterine contractions and premature delivery. Methods: between February 1996 and July 1998, 73 high risk pregnant women for preterm delivery, between the 24th and 34th weeks of gestation, were submitted to uterine contraction monitoring with tokodynamometers for 1 hour twice a week. The positive test was the presence of 4 contractions/h before the 30th week of gestation, and after this time, 6 contractions/h. Result: of 73 women, 17 patients (23.28% were excluded from the final analysis because they presented obstetric problems or unfavorable development for the final result. The rate of preterm delivery was 21

  17. Evaluación de la involución, salud uterina y retorno de la actividad ovárica con la adición de zeolita 2% en la dieta basal de vacas lecheras

    OpenAIRE

    Garzón Prado, Juan Pablo

    2016-01-01

    El objetivo de esta investigación fue evaluar el efecto de zeolita (Clinoptilolita) adicionado en la dieta basal de vacas lecheras durante 105 días, 60 días pre-parto (dap) y 45 días post-parto (dpp) y su influencia en la involución (IU) y salud uterina (SU), el retorno de la actividad ovárica (AO) y la condición corporal (CC). El proyecto se realizó en tres ganaderías de la comunidad de Soldados del Cantón Cuenca – Azuay, en 50 vacas secas, con una CC ? 3,5, entre 2 a 5 partos, clínicamente ...

  18. Colgajos de perforantes de las arterias epigástricas inferiores profunda y superficial Deep and superficial inferior epigastric artery perforator flaps

    Directory of Open Access Journals (Sweden)

    A. R. Gagnon

    2006-12-01

    Full Text Available Con el desarrollo de los colgajos miocutáneos de recto abdominal (TRAM, el abdomen inferior ha sido reconocido como la principal área dadora de tejidos autólogos de alta calidad, especialmente útiles en reconstrucción mamaria. Más recientemente la habilidad para obtener componentes adiposocutáneos similares sin sacrificar el músculo recto ha revolucionado el campo de la Cirugía Reconstructiva. El advenimiento de los colgajos de perforantes ha permitido a los cirujanos plásticos lograr los mismos buenos resultados estéticos que con los colgajos miocutáneos tradicionales, pero con un considerable descenso en la morbilidad del área donante. Con los colgajos de perforantes de la arteria epigástrica inferior profunda (DIEP y de la arteria epigástrica inferior superficial (SIEA, los pacientes han incrementado sus opciones de reconstrucción. Este artículo revisa la anatomía quirúrgica de la pared abdominal relativa a los colgajos SIEA y DIEP. Se explican detalladamente los pasos principales para la preparación preoperatoria, la técnica quirúrgica y los cuidados postoperatorios. Se discuten las ventajas y desventajas y se presen- tan los trucos técnicos que pueden ayudar a mejorar el resultado final. Además se ilustran con ayuda de casos clínicos las indicaciones típicas y atípicas.Following the development of the transverse rectus abdominis myocutaneous (TRAM flap, the lower abdomen has been recognized as a prime source of high quality autogenous tissue, especially useful in breast reconstruction. More recently, the ability to harvest a similar adipocutaneous component without sacrifice of the rectus muscle has revolutionized the field of reconstructive surgery. The advent of perforator flaps has allowed plastic surgeons to achieve the same highly esthetic results as with the former myocutaneous flaps while significantly decreasing the donor site morbidity. With the deep inferior epigastric artery perforator (DIEP flap and

  19. Doppler obstétrico posterior al uso de Betametasona para la maduración pulmonar fetal

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    Keibis Jiménez Castillejo

    2014-04-01

    Full Text Available El objetivo de la investigación fue determinar las modificaciones del Doppler obstétrico posterior al uso de betametasona para la maduración pulmonar fetal. Se realizó una investigación de tipo explicativa, prospectiva y longitudinal con un diseño cuasi-experimental y una muestra no probabilística intencional de 106 pacientes que acudieron a la consulta Pre-natal de Alto Riesgo del Hospital Central “Dr. Urquinaona". Una vez seleccionadas las pacientes se les administró inyecciones intramusculares de betametasona (12 mg/día por dos días consecutivos. Se realizaron las mediciones de índice de pulsatilidad e índice de resistencia en las arterias uterinas, umbilical y cerebral media fetal. No se encontraron diferencias estadísticamente significativas entre las determinaciones del índice de pulsatilidad y de resistencia de las arterias uterinas (p = ns. Se observaron disminuciones significativas en el índice de pulsatilidad y de resistencia de la arteria umbilical en la segunda y tercera medición al compararla con la medición inicial (p < 0,05. Se encontraron disminuciones en el índice de pulsatilidad de la arteria cerebral media fetal en ambos periodos de estudio comparado con los valores iniciales y solo se observó una disminución significativa del índice de resistencia en la segunda medición (p < 0,05. Se concluye que el uso de betametasona para la maduración pulmonar fetal produce modificaciones en la evaluación Doppler de las arterias umbilical y cerebral media fetal. Obstetric doppler after use of Betamethasone for fetal lung maturation Abstract The objective of research was to determine modifications of obstetric Doppler after to fetal lung maturation. An explicative, prospective and longitudinal research was done with a quasi-experimental design and an intentional non probabilistic sample of 106 patients who assisted to High Risk Antenatal Consult at Hospital Central “Dr. Urquinaona". Once patients were selected

  20. Pseudo-aneurisma post-traumático de tronco de arteria coronaria izquierda Post-traumatic false (pseudo aneurysm of the left main coronary artery

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    Melina M. Gallo

    2011-08-01

    Full Text Available El pseudo-aneurisma de arteria coronaria es extremadamente raro. Su historia natural es poco conocida y su tratamiento discutido. Se presenta el caso de un paciente con pseudo-aneurisma de tronco de la coronaria izquierda e infarto antero-apical del ventrículo izquierdo cinco años después de un paro cardíaco secundario a un traumatismo no penetrante de tórax. Se consideró entonces que la lesión no era pasible de corrección percutánea o quirúrgica por lo que se optó por tratamiento médico conservador. Una angiografía coronaria por tomografía computarizada multicorte realizada 10 años después del evento inicial mostró ausencia de progresión de la lesión.Coronary pseudo-aneurysm is an extremely rare entity. Its natural history is scarcely known and its treatment is controversial. We report a case of pseudo-aneurysm of the left main coronary artery associated with an antero-apical infarct of the left ventricle diagnosed five years after a cardiac arrest following a non-penetrating thoracic trauma. The patient was treated conservatively because percutaneous or surgical correction were not considered suitable for this lesion. A multidetector computed tomography coronary angiogram performed 10 years after the initial event showed no evidence of progression.

  1. Osteomyelitis der Wirbelsäule und Bildung eines Abzesses am linken Oberschenkel nach Implantation eines endovaskulären Strents in die Arteria femoralis superficialis sinistra

    Directory of Open Access Journals (Sweden)

    Brodmann M

    2000-01-01

    Full Text Available Die perkutane transluminale Angioplastie (PTA mit nachfolgender Implantation von selbstexpandierbaren intravaskulären Stents ist mittlerweile eine etablierte Methode zur Behandlung von arteriosklerotischen Läsionen geworden. Nachfolgende septische Komplikationen dieses Eingriffes, manches Mal mit tödlichem Ausgang, sind in der Literatur beschrieben, gelten jedoch als sehr selten. Daher gibt es auch eine sehr kontroversielle Meinung über die prophylaktische Gabe von Antibiotika bei der Implantation von Stents. Wir beschreiben einen Patienten, dem ein gecoverter Stent in die Arteria femoralis superficialis sinistra implantiert wurde und bei dem sich nachfolgend ein Abszeß um den Stent entwickelte. Der Patient hatte weder vor der Stentimplantation eine prophylaktische, noch im Anschluß eine begleitende antibiotische Therapie erhalten. Nach Diagnose des Abszesses wurde der Patient antibiotisch massiv abgedeckt und konnte in zufriedenstellendem Allgemeinzustand nach Hause entlassen werde. Zu Hause jedoch setzte der Patient seine antibiotische Therapie ab. Daraufhin entwickelte der Patient Zeichen einer schweren Allgemeinsepsis mit einer Spondylodiscitis im Bereich von TH 12 und L1 mit prae- und paravertebraler Infiltration, so wie auch einen Abszeß im Bereich des linken Musculus psoas.

  2. Manejo de lesión traumática de arteria femoral con injerto autólogo de vena safena en zona de operaciones

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    M. Gascón Hove

    2015-03-01

    Full Text Available Tanto en el ámbito civil como en el militar, las lesiones vasculares de las extremidades inferiores son frecuentes y potencialmente mortales. Las medidas de soporte iniciales para combatir el shock, una actitud quirúrgica técnicamente correcta encaminada a reparar precozmente la vascularización del miembro y un control postoperatorio estricto y continuo son los pilares básicos del tratamiento. En condiciones óptimas, las tasas de amputación y de mortalidad se hallan por debajo del 10 y del 4%, respectivamente. Presentamos a continuación un caso de un militar afgano con una lesión con pérdida de substancia de la arteria femoral en el que se consiguió una revascularización inicial con un shunt temporal. Tras ser estabilizado y evacuado al ROLE 2 de Herat, se realizó un injerto autólogo de la vena safena contralateral.

  3. Coronary artery abnormalities in pediatric patients: classification. Anomalías de las arterias coronarias en pacientes pediátricos: clasificación.

    Directory of Open Access Journals (Sweden)

    José Jesús García Mendiola

    Full Text Available Coronary artery anomaly is defined as any anatomical pattern that is apart from the normal element in regard to their origin, number, distribution and course. Through different mechanisms, it could be the cause of t thoracic pain, sudden death, myocardiopathy, syncope, myocardial infarction and ventricular fibrillation. These constitute a group of malformations which can be classified into, congenital, acquired and associated to other cardiac entities malformations. Due to the importance of this topic for cardiologists and specifically to pediatric cardiologists, this bibliographical revision about abnormalities classification is carried out.
    Se define como anomalía de las arterias coronarias a cualquier patrón anatómico que se aparte de lo normal en lo referente a su origen, número, distribución y trayecto. Mediante diferentes mecanismos, pueden ser la causa de dolor torácico, muerte súbita, miocardiopatía, síncope, infarto de miocardio y fibrilación ventricular. Constituyen un grupo de malformaciones que pueden clasificarse en: congénitas, adquiridas y asociadas a otras entidades cardiacas. Por la importancia que reviste para cardiólogos en general y sobre todo para cardiólogos pediatras, se realiza una revisión bibliográfica acerca de la clasificación de estas anomalías.

  4. Epigastric and Umbilical Hernia; Work Relatedness and Return to Work

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    Ramin Mehrdad

    2013-03-01

    Full Text Available Abdominal wall hernia is common but reliable scientific data about its work relatedness is very limited and inconsistent. In this paper, a less common type of abdominal wall hernia in a 30 year old male worker is presented with recurrence after first surgery when he returned to work. In contrast with almost all kinds of hernia, a lifelong limitation for heavy lifting was recommended. It seems that contrary to popular belief, work relatedness of abdominal wall hernia is seriously doubtful, although conclusive evidences are not enough. It is preferable to make decisions cautiously for return to heavy duties of work after surgery of large umbilical, umbilical & epigastric or incisional hernia, while avoiding recommendations for long days off work after surgery of any hernia.

  5. Epigastric and umbilical hernia; work relatedness and return to work.

    Science.gov (United States)

    Mehrdad, Ramin; Sadeghniiat Haghighi, Khosro; Naseri Esfahani, Amir Hossein

    2013-01-01

    Abdominal wall hernia is common but reliable scientific data about its work relatedness is very limited and inconsistent. In this paper, a less common type of abdominal wall hernia in a 30 year old male worker is presented with recurrence after first surgery when he returned to work. In contrast with almost all kinds of hernia, a lifelong limitation for heavy lifting was recommended. It seems that contrary to popular belief, work relatedness of abdominal wall hernia is seriously doubtful, although conclusive evidences are not enough. It is preferable to make decisions cautiously for return to heavy duties of work after surgery of large umbilical, umbilical & epigastric or incisional hernia, while avoiding recommendations for long days off work after surgery of any hernia.

  6. Repair of congenital diaphragmatic hernias through umbilical skin incisions.

    Science.gov (United States)

    Uehara, Shuichiro; Usui, Noriaki; Kamiyama, Masafumi; Masahata, Kazunori; Nara, Keigo; Ueno, Takehisa; Soh, Hideki; Oue, Takaharu; Fukuzawa, Masahiro

    2013-05-01

    The use of thoracoscopy and laparoscopy in the treatment of congenital diaphragmatic hernias (CDHs) has been recently reported; however, the use of these procedures still remains controversial due to CO2 insufflation and limited working space. In addition, because of difficult techniques, it has not been widely accepted. Among CDH patients, mild cases whose lung is not hypoplastic, and not associated with persistent pulmonary hypertension of the neonate (PPHN) often develop small defects in the diaphragm that can be repaired using "direct closure." Because direct closure does not require as wide an operative field as that needed for patch closure, we repaired CDH through umbilical skin windows in two neonates with mild CDH to minimize the wounds. With the creation of additional radical small incisions, the surgeries were successfully performed without any intra- or postoperative complications, and the wounds were cosmetically pleasing. The repair of CDHs through umbilical skin windows is a feasible and useful approach in neonates with mild CDH.

  7. Umbilical cord clamping. An analysis of a usual neonatological conduct.

    Science.gov (United States)

    Papagno, L

    1998-01-01

    Here we described a critical analysis of the neonatological procedure of early cord clamping, meaning this, within 40 seconds after birth. Fifty three cases are here analysed, in which this practice was not performed, but instead a late umbilical cord clamping was done after birth or after the cord had stopped beating. Variations in hematocrito values within 24 to 36 hours after birth were studied. A transitory polycithemia, with a maximum peak 12 hours post-delivery was observed. These values returned to normal levels between 24 and 36 hours after birth. K vitamin was not administered to any of the newborns. No pathology appeared related to this transitory polycithemia. In can be concluded that the late umbilical cord clamping represents no risk to the new-born and that the pathological phenomena described under these circumstances may be attributed to the increase in K vitamin dependent coagulation factors that are induced by the routinary administration of phitonadione to all normal newborns.

  8. Pylephlebitis secondary to strangulated umbilical hernia with small bowel ischemia

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    Ennio Bruschi

    2013-08-01

    Full Text Available Pylephlebitis is a septic thrombophlebitis of the portal venous system that infrequently complicates small bowel infarction. We present a case of pylephlebitis with portomesenteric vein gas bubbles secondary to small bowel ischemia caused by a strangulated umbilical hernia, diagnosed on computed tomography (CT and confirmed in the operating theater. This case is an example of the usefulness of CT in early recognition of suggestive radiologic findings of pylephlebitis associated with intestinal ischemia for prompt treatment of the patient.

  9. Identifying Effectors of Outcomes in Patients with Large Umbilical Hernias.

    Science.gov (United States)

    Groene, Steven A; Heniford, Davis W; Prasad, Tanushree; Lincourt, Amy E; Augenstein, Vedra A

    2016-07-01

    Quality of life (QOL) has become an important focus of hernia repair outcomes. This study aims to identify factors which lead to ideal outcomes (asymptomatic and without recurrence) in large umbilical hernias (defect size ≥9 cm(2)). Review of the prospective International Hernia Mesh Registry was performed. The Carolinas Comfort Scale was used to measure QOL at 1-, 6-, and 12-month follow-up. Demographics, operative details, complications, and QOL data were evaluated using standard statistical methods. Forty-four large umbilical hernia repairs were analyzed. Demographics included: average age 53.6 ± 12.0 and body mass index 34.9 ± 7.2 kg/m(2). The mean defect size was 21.7 ± 16.9 cm(2), and 72.7 per cent were performed laparoscopically. Complications included hematoma (2.3%), seroma (12.6%), and recurrence (9.1%). Follow-up and ideal outcomes were one month = 28.2 per cent, six months = 42.9 per cent, one year = 55.6 per cent. All patients who remained symptomatic at one and two years were significantly symptomatic before surgery. Symptomatic preoperative activity limitation was a significant predictor of nonideal outcomes at one year (P = 0.02). Symptomatic preoperative pain was associated with nonideal outcomes at one year, though the difference was not statistically significant (P = 0.06). Operative technique, mesh choice, and fixation technique did not impact recurrence or QOL. Repair of umbilical hernia with defects ≥9 cm(2) had a surprising low rate of ideal outcomes (asymptomatic and no recurrence). All patients with nonideal long-term outcomes had preoperative pain and activity limitations. These data may suggest that umbilical hernia should be repaired when they are small and asymptomatic.

  10. Adherence of human basophils to cultured umbilical vein endothelial cells.

    OpenAIRE

    1988-01-01

    The mechanism by which circulating human basophils adhere to vascular endothelium and migrate to sites of allergic reactions is unknown. Agents have been identified which stimulate the adherence of purified basophils to cultured human umbilical vein vascular endothelial cells (HuVEC). Treatment of HuVEC with interleukin 1, tumor necrosis factor (TNF), bacterial endotoxin, and 12-O-tetradecanoylphorbol-13-acetate (TPA) resulted in time and dose-dependent increases of adhesiveness for basophils...

  11. Damage control apronectomy for necrotising fasciitis and strangulated umbilical hernia.

    LENUS (Irish Health Repository)

    Coyle, P

    2012-01-31

    We present a case of a 50-year-old morbidly obese woman who presented with a case of necrotizing fasciitis of the anterior abdominal wall due to a strangulated umbilical hernia. The case was managed through damage control surgery (DCS) with an initial surgery to stabilise the patient and a subsequent definitive operation and biological graft hernia repair. We emphasise the relevance of DCS principles in the management of severe abdominal sepsis.

  12. What has methylmercury in umbilical cords told us? - Minamata disease.

    Science.gov (United States)

    Yorifuji, Takashi; Kashima, Saori; Tsuda, Toshihide; Harada, Masazumi

    2009-12-20

    Severe methylmercury poisoning occurred in Minamata and neighboring communities in the 1950s and 1960s. The exposed patients manifested neurological signs, and some patients exposed in utero were born with so-called congenital Minamata disease. In a previous report, Nishigaki and Harada evaluated the methylmercury concentrations in the umbilical cords of inhabitants and demonstrated that methylmercury actually passed through the placenta (Nishigaki and Harada, 1975). However, the report involved a limited number of cases (only 35) and did not quantitatively evaluate the regional differences in the transition of methylmercury exposure. Therefore, in the present study, we evaluated the temporal and spatial distributions of methylmercury concentrations in umbilical cords, with an increased number of participants and additional descriptive analyses. Then, we examined whether the methylmercury concentrations corresponded with the history of the Minamata disease incident. A total of 278 umbilical cord specimens collected after birth were obtained from babies born between 1925 and 1980 in four study areas exposed to methylmercury. Then, we conducted descriptive analyses, and drew scatterplots of the methylmercury concentrations of all the participants and separated by the areas. In the Minamata area, where the first patient was identified in 1956, the methylmercury concentration reached a peak around 1955. Subsequently, about 5 years later, the concentrations peaked in other exposed areas with the expected exposure distribution corresponding with acetaldehyde production (the origin of methylmercury). This historical incident several decades ago in Minamata and neighboring communities clearly shows that regional pollution affected the environment in utero. Furthermore, the temporal and spatial distributions of the methylmercury concentrations in the umbilical cords tell us the history of the Minamata disease incident.

  13. Isolation of mesenchymal stem cells from equine umbilical cord blood

    OpenAIRE

    Thomsen Preben D; Heerkens Tammy; Koch Thomas G; Betts Dean H

    2007-01-01

    Background: There are no published studies on stem cells from equine cord blood although commercial storage of equine cord blood for future autologous stem cell transplantations is available. Mesenchymal stem cells (MSC) have been isolated from fresh umbilical cord blood of humans collected non-invasively at the time of birth and from sheep cord blood collected invasively by a surgical intrauterine approach. Mesenchymal stem cells isolation percentage from frozen-thawed human cord blood is lo...

  14. Nova pipeta para inseminação intra-uterina em suínos New pipette for intrauterine insemination in pigs

    Directory of Open Access Journals (Sweden)

    Gustavo Nogueira Diehl

    2006-02-01

    Full Text Available O objetivo deste trabalho foi avaliar o desempenho reprodutivo de 423 fêmeas suínas de ordem de parto 1 a 9 submetidas à inseminação intra-uterina (IAU, com um novo modelo de pipeta (T1 cuja extremidade não é fixada na cérvix ou uma pipeta de IAU modelo Verona® e que permite a fixação da sua extremidade em espiral na cérvix (T2. Para comparar as duas pipetas, foi considerado o grau de dificuldade para realização das inseminações, o tempo necessário para realizá-las, a presença de sangramento após a inseminação, a presença de refluxo no momento da inseminação, as taxas de retorno ao estro (TR, de prenhez (TPR e de parto ajustada (TPA, além do número de leitões nascidos (NT. As fêmeas de ambos os grupos foram inseminadas com doses de 1 bilhão de espermatozóides, em intervalos de 24 horas. A passagem do cateter de IAU através da cérvix foi possível em 95,9% das fêmeas, sem diferença entre os tratamentos (P>0,05. Em pelo menos uma das inseminações, foi observado sangue no cateter, após a realização da IAU, em 20,6% das fêmeas do T1 e 15,2% das fêmeas do T2 (P=0,14. O tempo médio necessário para realizar a inseminação foi de 2,1 minutos para o T1 e 2,3 minutos para o T2 (P=0,26. O percentual de fêmeas com refluxo de sêmen no momento da inseminação foi maior (P=0,01 no T1 (8,4% em comparação ao T2 (2,9%. Não houve diferença (P>0,05 nas variáveis TR (8,0 e 4,8%, TPR (93,4 e 96,2% e NT (12,4 e 12,7 leitões entre T1 e T2, respectivamente. A TPA do T1 (90,6% apresentou tendência (P=0,07 de ser inferior à do T2 (95,1%. No T1, as fêmeas primíparas apresentaram maior TR e menor TPA em comparação às pluríparas (PThe aim of this work was to evaluate the reproductive performance of 423 sows of 1 to 9 farrowings inseminated with two different intrauterine artificial insemination (IAU pipettes. The first group (T1 was formed by sows inseminated with a new pipette whose extremity was not fixed in the

  15. Malformação arteriovenosa uterina após doença trofoblástica gestacional Uterine arteriovenous malformation after gestational trophoblastic disease

    Directory of Open Access Journals (Sweden)

    Paulo Belfort

    2006-02-01

    Full Text Available OBJETIVO: investigar a presença e resultados de malformações vasculares uterinas (MAVU após doença trofoblástica gestacional (DTG. MÉTODOS: estudo retrospectivo com inclusão de casos diagnosticados entre 1987 e 2004; 2764 pacientes após DTG foram acompanhadas anualmente com ultra-sonografia transvaginal e Doppler colorido no Centro de Neoplasia Trofoblástica Gestacional da Santa Casa da Misericórdia (Rio de Janeiro, RJ, Brasil. Sete pacientes tiveram diagnóstico final de MAVU baseado em análise ultra-sonográfica - índice de pulsatilidade (IP, índice de resistência (IR e velocidade sistólica máxima (VSM - e achados de imagens de ressonância nuclear magnética (RNM. Dosagens negativas de beta-hCG foram decisivas para estabelecer o diagnóstico diferencial com DTG recidivante. RESULTADOS: a incidência de MAVU após DTG foi 0,2% (7/2764. Achados ultra-sonográficos de MAVU: IP médio de 0,44±0,058 (extremos: 0,38-0,52; IR médio de 0,36±0,072 (extremos: 0,29-0,50; VSM média de 64,6±23,99 cm/s (extremos: 37-96. A imagem de RNM revelou útero aumentado, miométrio heterogêneo, espaços vasculares tortuosos e vasos parametriais com ectasia. A apresentação clínica mais comum foi hemorragia transvaginal, presente em 52,7% (4/7 dos casos. Tratamento farmacológico com 150 mg de acetato de medroxiprogesterona foi empregado para controlar a hemorragia, após a estabilização hemodinâmica. Permanecem as pacientes em seguimento, assintomáticas até hoje. Duas pacientes engravidaram com MAVU, com gestações e partos exitosos. CONCLUSÃO: presente sangramento transvaginal em pacientes com beta-hCG negativo e história de DTG, deve-se considerar a possibilidade de MAVU e solicitar avaliação ultra-sonográfica com dopplervelocimetria. O tratamento conservador é a melhor opção na maioria dos casos de MAVU pós-DTG.PURPOSE: to investigate the presence and outcome of uterinevascular malformations (UVAM after gestational

  16. Umbilical hernia with cholelithiasis and hiatal hernia: a clinical entity similar to Saint's triad.

    Science.gov (United States)

    Yamanaka, Takahiro; Miyazaki, Tatsuya; Kumakura, Yuji; Honjo, Hiroaki; Hara, Keigo; Yokobori, Takehiko; Sakai, Makoto; Sohda, Makoto; Kuwano, Hiroyuki

    2015-01-01

    We experienced two cases involving the simultaneous presence of cholelithiasis, hiatal hernia, and umbilical hernia. Both patients were female and overweight (body mass index of 25.0-29.9 kg/m(2)) and had a history of pregnancy and surgical treatment of cholelithiasis. Additionally, both patients had two of the three conditions of Saint's triad. Based on analysis of the pathogenesis of these two cases, we consider that these four diseases (Saint's triad and umbilical hernia) are associated with one another. Obesity is a common risk factor for both umbilical hernia and Saint's triad. Female sex, older age, and a history of pregnancy are common risk factors for umbilical hernia and two of the three conditions of Saint's triad. Thus, umbilical hernia may readily develop with Saint's triad. Knowledge of this coincidence is important in the clinical setting. The concomitant occurrence of Saint's triad and umbilical hernia may be another clinical "tetralogy."

  17. Associations between intrapartum death and piglet, placental, and umbilical characteristics.

    Science.gov (United States)

    Rootwelt, V; Reksen, O; Farstad, W; Framstad, T

    2012-12-01

    Intrapartum death in multiparous gestations in sows (Sus scrofa) is often caused by hypoxia. There is little information in the literature on the assessment of the placenta in relation to intrapartum death in piglets. The aim of this study was to evaluate the impact of the placental area and weight upon piglet birth characteristics and intrapartum death. Litters from 26 Landrace-Yorkshire sows were monitored during farrowing and the status of each piglet was recorded, including blood parameters of piglets and their umbilical veins. Of 413 piglets born, 6.5% were stillborn. Blood concentrations of glucose, lactate, and CO(2) partial pressure were increased in the stillborn piglets (P piglets, whereas pH and base excess were decreased (P piglets born dead vs. live (P piglets born dead was not different from live-born piglets (P = 0.631), whereas mean body mass index was reduced (P piglets were not different from live-born piglets (P = 0.662 and P = 0.253, respectively). Blood concentrations of lactate, hemoglobin, and hematocrit recorded in all piglets pooled were associated with placental area (P 0.2). Piglet BW was positively correlated with placental area and placental weight (P piglet birth weight, but not with the probability of being born dead. Placental area was a better predictor of piglet vitality than placental weight. Because umbilical cord rupture and prolonged birth time were associated with being born dead, umbilical cord rupture and placental detachment seem to be probable causes of intrapartum death.

  18. Primary Hydatid Cyst of Umbilicus, Mimicking an Umbilical Hernia.

    Science.gov (United States)

    Tarahomi, Mohammadreza; Alizadeh Otaghvar, Hamidreza; Ghavifekr, Nazila Hasanzadeh; Shojaei, Daryanaz; Goravanchi, Farhood; Molaei, Amir

    2016-01-01

    Hydatid cyst caused by Echinococcus granulosus demonstrates an endemic infection in several countries such as Middle Eastern countries. Liver is the most frequently involved organ, followed by the lung. The case we present is solitary primary localization of cyst in abdominal wall which is extremely rare. A 57-year-old woman presented with an abdominal wall lesion in umbilical area that had been evolving for about 2 years with recent complaint of pain and discomfort. We detected a midline abdominal mass 12⁎13 centimeters in diameter which was bulged out in umbilicus. Preoperative clinical diagnosis of incarcerated umbilical hernia was made due to its physical examination while surgical exploration disproved the primary diagnosis and we found cystic mass adherent to superficial fascia without any communication to peritoneal space. The cyst was excised completely without any injury or perforation of containing capsule. The diagnosis of hydatid cyst was confirmed by histopathological examination of specimen. The retrograde evaluation showed no involvement of other organs. The patient was followed for two years and no recurrence of hydatid disease has been observed. Hydatid cyst should be considered as a differential diagnosis of abdominal wall and umbilical lesions especially in endemic regions.

  19. Laparoscopic management of urachal cyst associated with umbilical hernia.

    Science.gov (United States)

    Gregory, G C; Vijay, R; Ligaj, M; Shiwani, M H

    2011-02-01

    The urachal cyst is a rare clinical entity of a urachal remnant. It is usually asymptomatic but can present with haematuria, tumour, urachal stone and infection. We present a case of a 63-year-old lady with a body mass index (BMI) of 49 who presented with a painful swelling in the umbilical region associated with an umbilical hernia. An ultrasound and computed tomography (CT) scan showed a suspected herniation of an umbilical remnant cyst through a paraumbilical defect. Laparoscopy confirmed the urachal cyst of 3 cm in size with a band connected with the cyst down to the urinary bladder associated with a 3-cm paraumbilical hernia. We removed the cyst and repaired the hernia laparoscopically uneventfully, after which her recovery was perfect. Radiological and laparoscopic pictures have not been reported in the English literature before. Although this condition is very rare, we suggest that it should be considered in the differential diagnosis of painful paraumbilical swelling. CT scanning and laparoscopy seems to be valuable, especially in obese patients.

  20. Primary Hydatid Cyst of Umbilicus, Mimicking an Umbilical Hernia

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    Mohammadreza Tarahomi

    2016-01-01

    Full Text Available Hydatid cyst caused by Echinococcus granulosus demonstrates an endemic infection in several countries such as Middle Eastern countries. Liver is the most frequently involved organ, followed by the lung. The case we present is solitary primary localization of cyst in abdominal wall which is extremely rare. A 57-year-old woman presented with an abdominal wall lesion in umbilical area that had been evolving for about 2 years with recent complaint of pain and discomfort. We detected a midline abdominal mass 12⁎13 centimeters in diameter which was bulged out in umbilicus. Preoperative clinical diagnosis of incarcerated umbilical hernia was made due to its physical examination while surgical exploration disproved the primary diagnosis and we found cystic mass adherent to superficial fascia without any communication to peritoneal space. The cyst was excised completely without any injury or perforation of containing capsule. The diagnosis of hydatid cyst was confirmed by histopathological examination of specimen. The retrograde evaluation showed no involvement of other organs. The patient was followed for two years and no recurrence of hydatid disease has been observed. Hydatid cyst should be considered as a differential diagnosis of abdominal wall and umbilical lesions especially in endemic regions.

  1. Acquired umbilical hernias in four captive polar bears (Ursus maritimus).

    Science.gov (United States)

    Velguth, Karen E; Rochat, Mark C; Langan, Jennifer N; Backues, Kay

    2009-12-01

    Umbilical hernias are a common occurrence in domestic animals and humans but have not been well documented in polar bears. Surgical reduction and herniorrhaphies were performed to correct acquired hernias in the region of the umbilicus in four adult captive polar bears (Ursus maritimus) housed in North American zoos. Two of the four bears were clinically unaffected by their hernias prior to surgery. One bear showed signs of severe discomfort following acute enlargement of the hernia. In another bear, re-herniation led to acute abdominal pain due to gastric entrapment and strangulation. The hernias in three bears were surgically repaired by debridement of the hernia ring and direct apposition of the abdominal wall, while the large defect in the most severely affected bear was closed using polypropylene mesh to prevent excessive tension. The cases in this series demonstrate that while small hernias may remain clinically inconsequential for long periods of time, enlargement or recurrence of the defect can lead to incarceration and acute abdominal crisis. Umbilical herniation has not been reported in free-ranging polar bears, and it is suspected that factors such as body condition, limited exercise, or enclosure design potentially contribute to the development of umbilical hernias in captive polar bears.

  2. Good practices in collecting umbilical cord and placental blood

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    Lauren Auer Lopes

    Full Text Available Abstract Objective: to identify the factors related to the quality of umbilical cord and placental blood specimens, and define best practices for their collection in a government bank of umbilical cord and placental blood. Method: this was a descriptive study, quantitative approach, performed at a government umbilical cord and placental blood bank, in two steps: 1 verification of the obstetric, neonatal and operational factors, using a specific tool for gathering data as non-participant observers; 2 definition of best practices by grouping non-conformities observed before, during and after blood collection. The data was analyzed using descriptive statistics and the following statistical software: Statistica(r and R(r. Results: while there was a correlation with obstetrical and neonatal factors, there was a larger correlation with operational factors, resulting in the need to adjust the professional practices of the nursing staff and obstetrical team involved in collecting this type of blood. Based on these non-conformities we defined best practices for nurses before, during and after blood collection. Conclusion: the best practices defined in this study are an important management tool for the work of nurses in obtaining blood specimens of high cell quality.

  3. Umbilical Cord Blood: Counselling, Collection, and Banking.

    Science.gov (United States)

    Armson, B Anthony; Allan, David S; Casper, Robert F

    2015-09-01

    Objectif : Analyser les données probantes actuelles sur le counseling, le prélèvement et la mise en banque, en ce qui a trait au sang de cordon ombilical, et fournir des lignes directrices aux professionnels canadiens de la santé en ce qui concerne la sensibilisation des patientes, le consentement éclairé, les aspects techniques et les options pour la mise en banque de sang de cordon au Canada. Options : Prélèvement sélectif ou systématique et mise en banque du sang de cordon ombilical, en vue de futures greffes autologues (chez le patient même) ou allogéniques (lien de parenté ou non) de cellules souches visant la prise en charge de troubles malins et bénins chez les enfants et les adultes. Le sang de cordon peut être prélevé au moyen de techniques in utero ou ex utero. Issues : Counseling, prélèvement et mise en banque en ce qui a trait au sang de cordon ombilical, formation des professionnels de la santé, indications du prélèvement de sang de cordon, risques et avantages à court et à long terme, morbidité maternelle et périnatale, satisfaction parentale et coûts de santé. Résultats : La littérature publiée a été récupérée par l’intermédiaire de recherches menées dans Medline et PubMed à partir de septembre 2013, au moyen d’un vocabulaire contrôlé (p. ex. « fetal blood », « pregnancy », « transplantation », « ethics ») et de mots clés (p. ex. « umbilical cord blood », « banking », « collection », « pregnancy », « transplantation », « ethics », « public », « private ») MeSH appropriés. Les résultats ont été restreints aux analyses systématiques, aux études observationnelles et aux essais comparatifs randomisés / essais cliniques comparatifs. Aucune limite n’a été imposée en matière de date, mais les résultats ont été limités aux articles publiés en anglais ou en français. Les recherches ont été mises à jour de façon régulière et int

  4. Cross-section of subsea umbilical and stress prediction of its structural components

    OpenAIRE

    Solovev V. V.; Zyatikov P. N.; Kozyrev I. N.

    2017-01-01

    It is presented in this article analysis of two models of subsea umbilicals under axial stress. Subsea umbilicals play a crucial role in offshore petroleum production and are designed to withstand all the environmental dynamic loads during the production period as long as 25 years. Apart from dynamic loads subsea umbilicals are under thermal loads as well having impact on the structural components and changing the material properties in some cases. The cross-section arrangement is a major par...

  5. Incarceration of umbilical hernia after radiological insertion of a Denver peritoneovenous shunt.

    Science.gov (United States)

    Ohta, Kengo; Shimohira, Masashi; Hashizume, Takuya; Kawai, Tatsuya; Kurosaka, Kenichiro; Suzuki, Kazushi; Watanabe, Kenichi; Shibamoto, Yuta

    2013-03-01

    We report a rare complication of incarceration of an umbilical hernia after Denver peritoneovenous shunt placement. A 50-year-old man presented with refractory ascites from liver cirrhosis. He also had an umbilical hernia. Because the ascites became uncontrollable, Denver peritoneovenous shunting was performed. The operation was successful and the ascites decreased. Ten days later, however, incarceration of the umbilical hernia occurred. A surgical repair was performed, but he died 2 days later. The cause of death was considered to be sepsis.

  6. Umbilicoplasty for large protruding umbilicus accompanying umbilical hernia: a simple and effective technique.

    Science.gov (United States)

    Ikeda, Hitoshi; Yamamoto, Hideki; Fujino, Junko; Kisaki, Yoshiyuki; Uchida, Hiroo; Ishimaru, Yuki; Hasumi, Toshiaki; Hamajima, Akito

    2004-02-01

    A large umbilical protrusion with redundant skin accompanying an umbilical hernia sometimes needs umbilicoplasty. Although several different techniques for making umbilical depression have been used, the results of the plastic surgery are sometimes unsatisfactory due to postoperative flattening or disappearance of the umbilical depression. To make a permanent umbilical depression that is cosmetically acceptable, we have modified the techniques. Umbilicoplasty was performed in 14 children whose ages ranged from 6 months-6 years and 3 months (median, 1 year and 10 months) and who had umbilical hernia with a large umbilical protrusion. After the fascial defect was closed, the diameter of the umbilicus was reduced to half that before surgery by removing fan-shaped skin flaps and approximating skin edges, and then inverting the umbilicus and fixing it caudally to the fascia and skin. There were no postoperative complications, and no flattening or disappearance of umbilical depression was observed during the follow-up of 10-19 months. The authors' technique of umbilicoplasty for a large protruding umbilicus accompanying umbilical hernia is a simple method that produces acceptable cosmetic results.

  7. Umbilical endometriosis mimicking as papilloma to general surgeons: A case report

    Directory of Open Access Journals (Sweden)

    A Singh

    2012-05-01

    Full Text Available IntroductionCutaneous or umbilical endometriosis is a rare entity that isoften overlooked because of chronic abdominal pain. Wepresent a case of umbilical hernia that presented to thegeneral surgeons due to chronic abdominal pain and nodulein the umbilicus, which was clinically diagnosed as umbilicalpapilloma.Case presentationA 48-year old multiparous Caucasian woman presented withpainful nodule in the umbilicus for two and half years. Thenodule was excised and the histopathological diagnosis wasumbilicus endometriosis.ConclusionUmbilical endometriosis is a very rare disease but should beconsidered as a differential diagnosis in women presentingwith umbilical swelling.

  8. Estudo dopplerfluxométrico das artérias uterinas antes e após inserção do DIU Color doppler flow analysis of the uterine arteries before and after DIU insertion

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    Marco Aurélio Martins de Souza

    2004-06-01

    Full Text Available OBJETIVO: averiguar se ocorrem alterações nos parâmetros da dopplervelocimetria em usuárias do dispositivo intra-uterino (DIU T cobre 380, por meio do estudo das artérias uterinas antes e depois da inserção do DIU em mulheres lactantes e não lactantes. MÉTODOS: ensaio clínico prospectivo, analítico, com 100 pacientes, em que avaliamos à dopplervelocimetria: índice de resistência (IR, índice de pulsatilidade (IP e relação sístole/diástole (SD. As pacientes selecionadas foram submetidas à avaliação pré-inserção do DIU e a novos exames pós-inserção, realizados com 30 dias (um ciclo e com 90 dias (três ciclos. RESULTADOS: os valores obtidos nas artérias uterinas no grupo antes da inserção do DIU foram de 0,9 para o IR, de 2,4 para o IP e de 10,0 para a relação SD. Os valores 30 dias após a inserção do DIU foram de 0,9 para o IR, de 2,5 para o IP e de 10,7 para a relação SD. Após três ciclos aferimos um valor de 0,9 para o IR, de 2,5 para o IP e de 10,7 para a relação SD. A comparação dos resultados obtidos antes e depois da inserção do DIU mostrou valor p de 0,51 para o IR, de 0,37 para o IP e de 0,51 para a relação SD, demonstrando que após a inserção, não houve modificações significativas na dopplervelocimetria. CONCLUSÕES: o uso do DIU T cobre 380 não tem efeito nos índices de dopplervelocimetria das artérias uterinas tanto em pacientes amamentando ou não.OBJECTIVE: to observe if there is any alteration in the Dopplervelocimetry of the uterine arteries of nursing and not nursing women after the insertion of the copper T 380 intrauterine device (IUD. METHODS: prospective, analytical, self-paired clinical assay, with 100 patients in whom we evaluated the color doppler flow: resistance index (RI, pulsative index (PI and systole/diastole (SD ratio. Nursing and not nursing women were assessed before IUD insertion as well as 30 days (one cycle and 90 days (three cycles after the insertion

  9. ANGIOPLASTIA PERCUTÁNEA CON STENT EN EL TRONCO PRINCIPAL DE LA ARTERIA CORONARIA IZQUIERDA / Percutaneous angioplasty with stent in the left main coronary artery

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    Javier Almeida Gómez

    2012-10-01

    Full Text Available ResumenIntroducción y objetivos: La afectación significativa del tronco común izquierdo, es la más letal de las presentaciones de la enfermedad arterial coronaria. El tratamiento de elección, es la cirugía de derivación aorto-coronaria. En varios estudios multicéntricos, se sugiere la posibilidad de tratar la enfermedad de tronco mediante el intervencionismo coronario percutáneo con implantación de prótesis endoluminal o stent. El objetivo de esta investigación fue caracterizar la angioplastia percutánea con stent en el tronco principal de la arteria coronaria izquierda. Método: Se realizó un estudio observacional, descriptivo y transversal en 21 pacientes con angioplastia percutánea con stent en el tronco principal de la arteria coronaria izquierda, realizadas en el laboratorio de Hemodinámica y Cardiología Intervencionista del Hospital "Hermanos Ameijeiras", entre enero 2010 y julio 2011. Resultados: No existió diferencia significativa en el sexo. Predominó el grupo de edad entre 50-64 años (47,6 % y el color de la piel blanca (76,19 %. El factor de riesgo cardiovascular más encontrado fue la HTA (85,71 %, seguido de dislipidemia (47,61 %. El diagnóstico más observado fue la angina de esfuerzo estable, 14 casos (66,66 %. La lesión en el cuerpo del tronco (12 pacientes, 57,1 %, fue la más encontrada, seguida de la ostial (8 casos. El tipo de stent más utilizado fue el liberador de fármacos (61,9 %, y solamente 4 pacientes presentaban troncos protegidos quirúrgicamente. Conclusiones: La mayor cantidad de casos fueron electivos, con predominio de los troncos no protegidos. El factor de riesgo coronario más encontrado fue la HTA. Se encontró asociación significativa entre la diabetes mellitus y la localización ostial de la lesión tratada. / AbstractIntroduction and Objectives: Significant impairment of the left main coronary artery is the most lethal presentation of coronary artery disease. The treatment of choice

  10. Cuantificación del signo de la arteria cerebral media hiperdensa con TCMD Quantification of hyperdense middle cerebral artery sign by multidetector computed tomography (MDCT.

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    Francisco Meli

    2011-12-01

    Full Text Available Objetivos. Obtener una cuantificación absoluta y relativa de la densidad en el signo de la arteria cerebral media (ACM con el fin de lograr un valor objetivo para el diagnóstico temprano de isquemia cerebral aguda con TCMD. Materiales y Métodos. Se incluyeron 40 pacientes, 20 con sospecha de isquemia cerebral aguda (edad media 73,4 años y 20 pacientes controles (edad media 71,2 años, p=0,63, que se realizaron TC cerebral con un equipo de 64 filas de detectores. La cuantificación absoluta se realizó midiendo la densidad en UH en el segmento de la ACM visualmente de mayor densidad. También se midió la densidad en el mismo segmento de la ACM contralateral para calcular la diferencia entre ambas arterias (cuantificación relativa. Resultados. En pacientes casos, la densidad media de la ACM afectada (62,5 UH, IC 99%: 46,2-78,7 fue mayor que la de la ACM contralateral (39,3 UH, IC 99%: 33,3-45,3 (p=0,0004 y también fue mayor en comparación con la ACM en pacientes controles (44,7 UH, IC 99%: 37,4-52 (p=0,0045. En la cuantificación relativa, la diferencia media entre la densidad de la ACM afectada y la de ACM contralateral en los pacientes casos fue de 23,2 UH (IC 95%: 11,7-34,7, mientras que, en pacientes controles, la diferencia media entre la densidad de la ACM derecha y la ACM izquierda fue 5,2 UH (IC 95%: 2,4-8,4 (diferencia: 17,8 UH, p=0,0032, IC 95%: 6,8-28,8. Conclusión. Mostramos diferencias significativas (absolutas y relativas en la densidad de la ACM en pacientes con sospecha de isquemia cerebral aguda en comparación con sujetos normales.Purposes. To obtain absolute and relative quantification values of density in the middle cerebral artery (MCA sign, in order to obtain an objective value for an early diagnosis of acute ischemic stroke using MDCT. Material and Methods. Forty adult patients, 20 with suspected diagnosis of acute ischemic stroke (mean age: 73.4 years and 20 controls (mean age: 71.2 years, p=0.63, underwent brain

  11. Utilidad de la derivación aVR en la identificación de la arteria responsable en el infarto inferior

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    Yanina B. Castillo Costa

    2006-01-01

    Full Text Available El ECG es el método más simple para el diagnóstico de infarto inferior (IAMinf; sin embargo, su utilidad disminuye para determinar el vaso responsable. Objetivos 1. Analizar la utilidad del desnivel del ST en aVR en la identificación de oclusión de las arterias coronaria derecha (CD o circunfleja (CX. 2. Evaluar la utilidad agregada a los criterios clásicos. Material y métodos Se incluyeron en el estudio 65 pacientes con IAMinf a quienes se les realizó una cinecoronariografía (CCG durante la internación. Se analizaron los criterios clásicos, así como el desnivel del ST en aVR: ?ST =?1 mm, ?ST =?1 mm o nivelado (isoST a 0,08 seg del punto J y se calcularon la sensibilidad (S, la especificidad (E, el valor predictivo positivo (VPP, el valor predictivo negativo (VPN y el likelihood ratio (LR. Se incluyó la derivación aVR en un análisis multivariado para determinar su valor agregado a los criterios clásicos. Resultados La CD fue responsable de la oclusión en 47 pacientes (72% y la CX en 18 (28%. Signos clásicos : CD : la relación del ?STD3/D2 =?1 se halló en 52 pacientes (91,5%; p = 0,001 e ?STD1-aVL =?1 mm en 34 (61%; p 1 en 13 pacientes (50%; p = 0,001 y ?STV5-V6 =?1 mm en 12 (44%; p < 0,001. Derivación aVR : CD : ?ST o isoST en 46 pacientes (81%; p < 0,001; CX : ?ST =?1 mm en 19 (56%; p < 0,001. En el análisis multivariado, el ?ST o isoST en aVR identificó a la CD (OR IC 95% 4,7 (1,1-19,8; p = 0,03, mientras que el ?ST aVR identificó a la CX. Se propone un algoritmo diagnóstico para CD que refleja el valor aditivo de aVR a la presencia de los signos clásicos: ?ST o isoST en aVR (VPP 94%; LR+: 2. Conclusión La derivación aVR es una herramienta útil para la identificación de la arteria responsable en el IAMinf, ya que brinda información diagnóstica adicional a los signos clásicos.

  12. Adaptación del algoritmo MARACAS para segmentación de la arteria carótida y cuantificación de estenosis en imágenes TAC

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    Doré Vincent

    2010-12-01

    Full Text Available En este artículo se describen las adaptaciones hechas al algoritmo MARACAS para segmentar y cuantificar estructuras vasculares en imágenes TAC de la arteria carótida. El algoritmo MARACAS, que está basado en un modelo elástico y en un análisis de los valores y vectores propios de la matriz de inercia, fue inicialmente diseñado para segmentar una sola arteria en imágenes ARM. Las modificaciones están principalmente enfocadas a tratar las especificidades de las imágenes TAC, así como la presencia de bifurcaciones. Los algoritmos implementados en esta nueva versión se clasifican en dos niveles. 1 Los procesamientos de bajo nivel (filtrado de ruido y de artificios direccionales, presegmentación y realce destinados a mejorar la calidad de la imagen y presegmentarla. Estas técnicas están basadas en información a priori sobre el ruido, los artificios y los intervalos típicos de niveles de gris del lumen, del fondo y de las calcificaciones. 2 Los procesamientos de alto nivel para extraer la línea central de la arteria, segmentar el lumen y cuantificar la estenosis. A este nivel, se aplican conocimientos a priori sobre la forma y anatomía de las estructuras vasculares. El método fue evaluado en 31 imágenes suministradas en el concurso “Carotid Lumen Segmentation and Stenosis Grading Grand Challenge” 2009. Los resultados obtenidos en la segmentación arrojaron un coeficiente de similitud de Dice promedio de 80.4% comparado con la segmentación de referencia, y el error promedio de la cuantificación de estenosis fue 14.4%.

  13. Comparação entre a histerossonografia, a histeroscopia e a histopatologia na avaliação da cavidade uterina de mulheres na pós-menopausa

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    Accorsi Neto Alfeu Cornélio

    2003-01-01

    Full Text Available OBJETIVOS: comparar os resultados da hístero-sonografia com os da histeroscopia e com os da histopatologia em mulheres na pós-menopausa. MÉTODOS: realizou-se hísterossonografia, histeroscopia e biópsia endometrial dirigida em 58 mulheres que tinham eco endometrial maior que 4 mm, idade superior a 40 anos, tempo de amenorréia superior a um ano e níveis de hormônio folículo-estimulante maiores que 35 mUI/mL. Foram excluídas as pacientes que fizeram uso de hormonioterapia, assim como aquelas com fatores que impedissem a realização dos exames de hísterossonografia, histeroscopia ou o estudo histopatológico. A análise estatística foi obtida pelos testes G de Cochran e McNemar. Foram calculados os valores de sensibilidade, especificidade e preditivos positivo e negativo da hístero-sonografia comparados com os outros exames. RESULTADOS: as taxas de concordância da hísterossonografia comparada aos achados histerpscópicos e histológicos foram de 94,8 e 77,6%, respectivamente. A sensibilidade e a especificidade na detecção de anormalidade da cavidade endometrial da hísterossonografia comparadas com a histeroscopia foram de 98 e de 75%, respectivamente. Já os valores preditivos positivo e negativo da hístero-sonografia foram de 96 e de 86%, respectivamente. Na comparação ao estudo histopatológico para o diagnóstico de alterações da cavidade endometrial, a hísterossonografia revelou sensibilidade de 98%, especificidade de 33% e os valores preditivos positivo e negativo foram de 76 e de 86%, respectivamente. Ressalta-se que das onze pacientes com sinéquia uterina diagnosticada pela hísterossonografia, duas tiveram hiperplasia endometrial. Houve um caso de cavidade normal pela hístero-sonografia em que o resultado da biópsia foi hiperplasia endometrial simples. CONCLUSÕES: nossos dados sugerem que a hísterossonografia tem boa sensibilidade comparada com a histeroscopia. Contudo, há limitações deste método diagn

  14. Correlación y concordancia entre ecocardiografía y cateterismo cardiaco derecho para determinación de la presión sistólica de arteria pulmonar

    OpenAIRE

    Aguilera Pacheco, Emil Alberto; Conde Camacho, Rafael; Perez-Fernandez, Oscar-Mauricio

    2015-01-01

    Introducción. El cateterismo cardiaco derecho representa el estándar de referencia para el diagnóstico de hipertensión pulmonar, sin embargo el rendimiento de la ecocardiografía como estudio inicial ha mostrado buena correlación con las variables medidas por cateterismo. El presente estudio pretende describir el grado de correlación y concordancia entre la ecocardiografía y el cateterismo cardiaco derecho para la medición de la presión sistólica de la arteria pulmonar. Materiales y méto...

  15. Revisao de 15 casos submetidos a oclusao temporaria bilateral de arteria iliaca interna em pacientes com alto risco para hemorragia obstetrica

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    Mariana Krutman

    2013-09-01

    Full Text Available OBJETIVO: Analisar os resultados de 15 pacientes com elevado risco de sangramento obstétrico, submetidas ao implante de catéteres balão profilático para oclusão temporária das artérias hipogástricas. MÉTODOS: Uma análise retrospectiva foi realizada com base em prontuários de 15 pacientes submetidas ao implante de catéteres balão profilático, de janeiro/2008 a dezembro/2011. Todas as pacientes incluídas no estudo foram diagnosticadas no período antenatal com doença placentária associada a alto risco de hemorragia obstétrica. RESULTADOS: A média de idade das pacientes estudadas foi de 36 anos (32-42 anos. Nove pacientes eram portadoras de acretismo placentário, quatro possuíam placenta prévia, uma estava com gestação ectópica e uma apresentava miomatose uterina e coagulopatia associada a Lupus Eritematosos Sistêmico. O volume total de contraste utilizado para o procedimento variou entre 20 e 160 ml (média de 84 ml. A média do número total de dias de internação e o número de dias de internação após o procedimento foram, respectivamente, 12,4 e 4,9 dias. Em oito (53% casos, não houve necessidade de transfusão sanguínea no intraoperatório ou após a cirurgia. A média do número de unidades de sangue transfundida foi 2,06. A única complicação associada ao procedimento foi a trombose arterial de artéria ilíaca externa, observada em dois casos. CONCLUSÃO: A oclusão temporária de artérias hipogástricas é um método seguro e efetivo para controle de hemorragia em pacientes com elevado risco de sangramento obstétrico, quando realizado por equipe experiente. Os resultados deste estudo são observacionais, retrospectivos e não randomizados; portanto, não podemos apoiar o uso rotineiro dessa técnica, mas podemos incluí-la no arsenal de recursos para casos selecionados com potencial para sangramento.

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  20. Umbilical Plugoma Mimics Melanoma Metastasis on FDG PET/CT.

    Science.gov (United States)

    Alabed, Yazan Z; Sakellis, Christopher

    2015-10-01

    An 84-year-old man with history of left forehead melanoma was found on a restaging F-FDG PET/CT scan with hypermetabolic lung nodules and a mildly FDG-avid soft tissue nodule posterior to the umbilicus. Biopsy of a right lower lobe nodule revealed metastatic melanoma. Follow-up posttreatment PET/CT scan showed complete resolution of lung nodules and unchanged FDG uptake at the level of the umbilicus. Review of the patient's medical history revealed a remote history of umbilical hernia repair. We present a case of postsurgical plugoma mimicking the appearance of melanoma metastasis on FDG PET/CT.

  1. Meckel′s diverticulum strangulated in an umbilical hernia

    Directory of Open Access Journals (Sweden)

    Komlatse Akakpo-Numado

    2009-01-01

    Full Text Available Background: Strangulated Meckel′s diverticulum (MD in an umbilical hernia (UH is a rare event. We present herein a case of strangulated MD in UH in a child. Case Report: An 18-month girl was admitted with clinical features suggesting upper intestinal strangulation since seven days. Many attempts of reduction were done before admission. She was resuscitated and had exploratory laparotomy, which revealed the hernia sac containing a completely gangrenous MD. She had bowel resection and had an uneventful postoperative period. Conclusion: An MD may be the content of a strangulated UH. Bowel resection of the segment bearing the diverticulum is advisable if the latter is gangrenous.

  2. On Complete Totally Real Pseudo-Umbilical Submanifolds in a Complex Projective Space

    Institute of Scientific and Technical Information of China (English)

    Min LIU; Wei Dong SONG

    2011-01-01

    Let Mn be a totally real pseudo-umbilical submanifold in a complex projective space CPn+p.In this paper,we study the position of completeness of Mn.By choosing a suitable frame field,we obtain a rigidity theorem such that Mn becomes totally umbilical submanifold and improve the related results.

  3. Entire liver as the only content of hernia of the umbilical cord.

    Science.gov (United States)

    Zameer, M M; Mahalik, S; Kanojia, R; Rao, K L N

    2012-10-01

    Hernia of the umbilical cord is a small omphalocoele with the abdominal defect being less than 4 cm and the small intestine being the usual content. We report a rare case of hernia of the umbilical cord with the whole of the liver herniating through the small defect into the sac as the only content. The pertinent literature is also reviewed.

  4. Nationwide prospective study on readmission after umbilical or epigastric hernia repair

    DEFF Research Database (Denmark)

    Helgstrand, F; Jørgensen, L N; Rosenberg, J;

    2013-01-01

    The primary aim of the present study was to investigate risk factors for readmission after elective umbilical and epigastric hernia repair and secondarily to evaluate causes for readmission.......The primary aim of the present study was to investigate risk factors for readmission after elective umbilical and epigastric hernia repair and secondarily to evaluate causes for readmission....

  5. Umbilical cord blood lactate: a valuable tool in the assessment of fetal metabolic acidosis

    DEFF Research Database (Denmark)

    Gjerris, Anne Cathrine Roslev; Staer-Jensen, Jette; Jørgensen, Jan Stener;

    2008-01-01

    The aim of the present study was (1) to evaluate the relationship between umbilical cord arterial blood lactate and pH, standard base excess (SBE), and actual base excess (ABE) at delivery and (2) to suggest a cut-off level of umbilical cord arterial blood lactate in predicting fetal asphyxia usi...

  6. Umbilical cord blood lactate: a valuable tool in the assessment of fetal metabolic acidosis

    DEFF Research Database (Denmark)

    Gjerris, A.C.; Staer-Jensen, J.; Jorgensen, J.S.;

    2008-01-01

    OBJECTIVE: The aim of the present study was (1) to evaluate the relationship between umbilical cord arterial blood lactate and pH, standard base excess (SBE), and actual base excess (ABE) at delivery and (2) to suggest a cut-off level of umbilical cord arterial blood lactate in predicting fetal a...

  7. Umbilical Cord Mercury Concentration as Biomarker of Prenatal Exposure to Methylmercury

    DEFF Research Database (Denmark)

    Grandjean, Philippe; Budtz-Jørgensen, Esben; Jørgensen, Poul J.

    2005-01-01

    biomarker, exposure assessment, food contamination, hair analysis, mercury/analysis, methylmercury compounds/analysis, organomercury compounds/blood, pregnancy, prenatal exposure delayed effects, preschool child, seafood, umbilical cord.......biomarker, exposure assessment, food contamination, hair analysis, mercury/analysis, methylmercury compounds/analysis, organomercury compounds/blood, pregnancy, prenatal exposure delayed effects, preschool child, seafood, umbilical cord....

  8. Development of Decellularized Human Umbilical Arteries as Small-Diameter Vascular Grafts

    Science.gov (United States)

    Gui, Liqiong; Muto, Akihito; Chan, Stephen A.; Breuer, Christopher K.

    2009-01-01

    Objective Developing a tissue-engineered small-diameter (<6 mm) vascular graft for reconstructive surgery has remained a challenge for the past several decades. This study was conducted to develop a decellularized umbilical artery and to evaluate its composition, endothelial cell compatibility, mechanical properties, and in vivo stability for potential use as a small-diameter vascular graft. Methods and Results Human umbilical arteries were isolated and decellularized by incubation in CHAPS and sodium dodecyl sulfate buffers followed by incubation in endothelial growth media-2. Decellularized umbilical arteries were completely devoid of cellular and nuclear material while retaining the integrity of extracellular collagenous matrix. The mechanical strength of the decellularized umbilical artery as assessed by its burst pressure in vitro showed no significant change from its native form. Decellularized umbilical arteries supported endothelial adherence as indicated by the re-endotheliazation with a monolayer of human umbilical vein endothelial cells. Furthermore, decellularized vessels that were implanted into nude rats as abdominal aorta interposition grafts remained mechanically intact and patent for up to 8 weeks. Conclusion Decellularized human umbilical arteries preserved the extracellular matrix, supported endothelialization, and retained function in vivo for up to 8 weeks. These properties suggest the potential use of decellularized umbilical arteries as small-diameter vascular grafts. PMID:19207043

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  1. File list: InP.CDV.20.AllAg.Primary_umbilical_vein_endothelial_cells [Chip-atlas[Archive

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  10. Cross-section of subsea umbilical and stress prediction of its structural components

    Directory of Open Access Journals (Sweden)

    Solovev V. V.

    2017-01-01

    Full Text Available It is presented in this article analysis of two models of subsea umbilicals under axial stress. Subsea umbilicals play a crucial role in offshore petroleum production and are designed to withstand all the environmental dynamic loads during the production period as long as 25 years. Apart from dynamic loads subsea umbilicals are under thermal loads as well having impact on the structural components and changing the material properties in some cases. The cross-section arrangement is a major part of the entire process of subsea umbilicals design. That is why this research is focused on the design of cross-section and has an aim to calculate main impacts subsea umbilicals facing during exploitation.

  11. Catamenial Pain in Umbilical Hernia with Spontaneous Reduction: An Unusual Presentation of a Rare Entity.

    Science.gov (United States)

    Pandey, Divya; Sharma, Ritu; Salhan, Sudha

    2015-08-01

    Spontaneous umbilical endometriosis occurring in absence of any previous abdominal or uterine surgery is extremely atypical. Its association with umbilical hernia is very rare and hernia getting spontaneously resolved has not been reported in literature so far. Here we report a case of a patient with spontaneous umbilical endometriosis associated with umbilical hernia which led to spontaneous hernia reduction. This was also associated with multiple uterine fibromyoma and bilateral ovarian endometrioma which were simultaneously treated by total abdominal hysterectomy with bilateral salpingo-oopherectomy along with surgical excision of the endometriotic tissue and repair of the abdominal wall defect. To the best of our knowledge, this is the first described case of spontaneous umbilical hernia reduction due to development of endometriosis.

  12. Anatomía del corazón y las arterias branquiales aferentes de las rayas (Chondrichthyes: Batoidea Anatomy of the heart and afferent branchial arteries of the rays (Chondrichthyes: Batoidea

    Directory of Open Access Journals (Sweden)

    Abraham Kobelkowsky

    2012-04-01

    Full Text Available Se selecionó el corazón y el sistema branquial aferente de Dasyatis sabina como patrón morfológico de los Batoidea. Se compararon las cámaras del corazón y la ramificación de la aorta ventral en las arterias branquiales aferentes con las correspondientes de especies representativas de otras familias de batoideos, tales como: Narcine brasiliensis (Narcinidae, Rhinobatos lentiginosus (Rhinobatidae, Raja texana (Rajidae, Urobatis jamaicensis (Urolophidae, Gymnura micrura (Gymnuridae y Myliobatis sp. (Myliobatidae. El análisis comparativo permitió reconocer como carácter más notable, la ausencia de las arterias innominadas posteriores en los Myliobatiformes, con excepción de Gymnuridae. Asimismo, permitió observar la amplia similitud entre Rhinobatidae y Rajidae, y entre Urotrygonidae y Dasyatidae.The heart and the afferent branchial system of the ray, Dasyatis sabina was selected as a morphologic pattern of the Batoidea. A comparison of the heart and the ramification of the ventral aorta into the branchial afferent arteries was made with the corresponding in representative species of other families of Batoidea, such as: Narcine brasiliensis (Narcinidae, Rhinobatos lentiginosus (Rhinobatidae, Raja texana (Rajidae, Urobatis jamaicensis (Urolophidae, Gymnura micrura (Gymnuridae, and Myliobatis sp. (Myliobatidae. The comparative analysis allows recognizing as the most notably character, the absence of the posterior innominates arteries in the Myliobatiformes, with the exception of Gymnuridae. A high similitude between Rhinobatidae and Rajidae, and Urolophidae and Dasyatidae was recognized.

  13. Exploración de las arterias coronarias de pacientes con síndrome de Tako-Tsubo con tomografía multislice: lesiones e inferencias fisiopatológicas

    Directory of Open Access Journals (Sweden)

    Omar Santaera

    2009-01-01

    Full Text Available Existen numerosos casos comunicados sobre la disfunción ventricular izquierda reversibleprecipitada por estrés emocional, pero su mecanismo no se conoce. En esta presentación sedescribe la evaluación de dos pacientes que consultaron con un cuadro clínico típico desíndrome de Tako-Tsubo, dolor precordial luego de un estrés emocional, disfunción ventricularizquierda transitoria y arterias coronarias angiográficamente normales. Con el objetivo deprofundizar el conocimiento de las arterias coronarias y la fisiopatología de esta enfermedad,a ambas se les realizó una tomografía multislice, en la que se evidenciaron lesionescoronarias similares a las halladas en accidentes de placa responsables de síndromescoronarios agudos. Si bien estos hallazgos deben completarse con estudios posteriores conun número mayor de pacientes, sugieren que al menos un subgrupo de pacientes con síndromede Tako-Tsubo tiene un sustrato fisiopatológico similar a los síndromes coronariosagudos.REV ARGENT CARDIOL 2009;77:227-230.

  14. Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction.

    Science.gov (United States)

    Acosta, Sandra A; Franzese, Nick; Staples, Meaghan; Weinbren, Nathan L; Babilonia, Monica; Patel, Jason; Merchant, Neil; Simancas, Alejandra Jacotte; Slakter, Adam; Caputo, Mathew; Patel, Milan; Franyuti, Giorgio; Franzblau, Max H; Suarez, Lyanne; Gonzales-Portillo, Chiara; Diamandis, Theo; Shinozuka, Kazutaka; Tajiri, Naoki; Sanberg, Paul R; Kaneko, Yuji; Miller, Leslie W; Borlongan, Cesar V

    2013-07-01

    Cell-based therapy is a promising therapy for myocardial infarction. Endogenous repair of the heart muscle after myocardial infarction is a challenge because adult cardiomyocytes have a limited capacity to proliferate and replace damaged cells. Pre-clinical and clinical evidence has shown that cell based therapy may promote revascularization and replacement of damaged myocytes after myocardial infarction. Adult stem cells can be harvested from different sources including bone marrow, skeletal myoblast, and human umbilical cord blood cells. The use of these cells for the repair of myocardial infarction presents various advantages over other sources of stem cells. Among these are easy harvesting, unlimited differentiation capability, and robust angiogenic potential. In this review, we discuss the milestone findings and the most recent evidence demonstrating the therapeutic efficacy and safety of the transplantation of human umbilical cord blood cells as a stand-alone therapy or in combination with gene therapy, highlighting the importance of optimizing the timing, dose and delivery methods, and a better understanding of the mechanisms of action that will guide the clinical entry of this innovative treatment for ischemic disorders, specifically myocardial infarction.

  15. Successful surgical management of ruptured umbilical hernias in cirrhotic patients.

    Science.gov (United States)

    Chatzizacharias, Nikolaos A; Bradley, J Andrew; Harper, Simon; Butler, Andrew; Jah, Asif; Huguet, Emmanuel; Praseedom, Raaj K; Allison, Michael; Gibbs, Paul

    2015-03-14

    Acute umbilical hernia rupture in patients with hepatic cirrhosis and ascites is an unusual, but potentially life-threatening complication, with postoperative morbidity about 70% and mortality between 60%-80% after supportive care and 6%-20% after urgent surgical repair. Management options include primary surgical repair with or without concomitant portal venous system decompression for the control of the ascites. We present a retrospective analysis of our centre's experience over the last 6 years. Our cohort consisted of 11 consecutive patients (median age: 53 years, range: 36-63 years) with advanced hepatic cirrhosis and refractory ascites. Appropriate patient resuscitation and optimisation with intravenous fluids, prophylactic antibiotics and local measures was instituted. One failed attempt for conservative management was followed by a successful primary repair. In all cases, with one exception, a primary repair with non-absorbable Nylon, interrupted sutures, without mesh, was performed. The perioperative complication rate was 25% and the recurrence rate 8.3%. No mortality was recorded. Median length of hospital stay was 14 d (range: 4-31 d). Based on our experience, the management of ruptured umbilical hernias in patients with advanced hepatic cirrhosis and refractory ascites is feasible without the use of transjugular intrahepatic portosystemic shunt routinely in the preoperative period, provided that meticulous patient optimisation is performed.

  16. Specificity of intraabdominal endoprosthesis of umbilical and postoperative ventral hernias

    Directory of Open Access Journals (Sweden)

    Grigoriev S.G.

    2012-03-01

    Full Text Available The research work objective was to examine the results of intraperitoneal plastics in the hernias of anterior abdominal wall. The experience of treatment of 89 patients with uncomplicated umbilical and postoperative ventral hernias was analized. The surgical treatment included an open intraperitoneal prosthetic hernioplasty. The hernial sac was not removed during the operation. The original techniques of treatment of hernia sac were used. Anatomical and morphological features in the structure of middle ventral hernias and their pathophysiological assessment were revealed. Practical recommendations for technology of intraperitoneal prosthesis were given. The early postoperative complications occurred: seroma (n=2, the outflow of serous fluid drainage for 5 days (n=1, infiltration of the umbilical area (n=3, suppuration of wounds (n=1. Vacuum drainage was performed in 24 patients after removal of large hernial defects. During the period from 6 months to 4 years recurrences were not revealed. The intraperitoneal surgery using a complex of musculo-aponeurotic tissues provided hernial implant fixation. Operation without the removal of the hernial sac reduced the trauma intervention. Method of suturing the surgical wound reduced the time of drainage and reduced the number of wound complications

  17. Optoacoustic measurements of human placenta and umbilical blood oxygenation

    Science.gov (United States)

    Nanovskaya, T. N.; Petrov, I. Y.; Petrov, Y.; Patrikeeva, S. L.; Ahmed, M. S.; Hankins, G. D. V.; Prough, D. S.; Esenaliev, R. O.

    2016-03-01

    Adequate oxygenation is essential for normal embryogenesis and fetal growth. Perturbations in the intrauterine oxidative environment during pregnancy are associated with several pathophysiological disorders such as pregnancy loss, preeclampsia, and intrauterine growth restriction. We proposed to use optoacoustic technology for monitoring placental and fetal umbilical blood oxygenation. In this work, we studied optoacoustic monitoring of oxygenation in placenta and umbilical cord blood ex vivo using technique of placenta perfusion. We used a medical grade, nearinfrared, tunable, optoacoustic system developed and built for oxygenation monitoring in blood vessels and in tissues. First, we calibrated the system for cord blood oxygenation measurements by using a CO-Oximeter (gold standard). Then we performed validation in cord blood circulating through the catheters localized on the fetal side of an isolated placental lobule. Finally, the oxygenation measurements were performed in the perfused placental tissue. To increase or decrease blood oxygenation, we used infusion of a gas mixture of 95% O2 + 5% CO2 and 95% N2 + 5% CO2, respectively. In placental tissue, up to four cycles of changes in oxygenation were performed. The optoacoustically measured oxygenation in circulating cord blood and in placental lobule closely correlated with the actual oxygenation data measured by CO-Oximeter. We plan to further test the placental and cord blood oxygenation monitoring with optoacoustics in animal and clinical studies.

  18. Deformation of the left and right ventricular longitudinal myocardium in fetuses with umbilical cord around neck

    Institute of Scientific and Technical Information of China (English)

    ZUO Dong-mei; WANG Chao-hong; WANG Yue-heng

    2012-01-01

    Background Umbilical cord around neck,a common obstetric complication,affects fetal hemodynamics.Does it influence fetal cardiac functions? The purpose of this study was to investigate the left and right ventricular systolic and diastolic functions of fetuses with umbilical cord around neck in the third trimester by applying velocity vector imaging (VVI).Methods Thirty-five cases of fetuses with umbilical cord around neck whose gestational ages from 35 to 40 weeks were selected,including 20 cases of umbilical artery ratio of the highest systolic velocity (S) to the lowest diastolic velocity (D) (S/D) <3.0 and 15 cases of umbilical artery S/D ≥3.0,while 20 cases of normal fetuses of 35-40 gestational weeks were selected as the control group.The changes in longitudinal velocity,strain,and strain rate of fetal left and right ventricle in systole and diastole in two groups,and the changes in fetal cardiac function under the situation of umbilical cord around neck were analyzed.Results Longitudinal strain and strain rate overall of fetal left and right ventricle in systole and diastole were less in fetuses with umbilical artery S/D ≥3.0 and umbilical cord around neck than those in fetuses with umbilical artery S/D <3.0and those in control group (P <0.05); there was no significant difference (P >0.05) in longitudinal strain and strain rate overall of fetal left and right ventricle in systole and diastole between fetuses with umbilical artery S/D <3.0 and those in control group.Conclusions Left and right ventricular systolic and diastolic dysfunction was detected in fetuses with umbilical cord around neck and umbilical artery S/D ≥3.0.WI could sensitively respond to cardiac function changes in fetuses with umbilical cord around neck,which provides another valuable method in the evaluation of fetal cardiac function.

  19. Estimation of the total number of mast cells in the human umbilical cord. A methodological study.

    Science.gov (United States)

    Engberg Damsgaard, T M; Windelborg Nielsen, B; Sørensen, F B; Henriques, U; Schiøtz, P O

    1992-09-01

    The aim of the present study was to estimate the total number of mast cells in the human umbilical cord. Using 50 microns-thick paraffin sections, made from a systematic random sample of umbilical cord, the total number of mast cells per cord was estimated using a combination of the optical disector and fractionated sampling. The mast cell of the human umbilical cord was found in Wharton's jelly, most frequently in close proximity to the three blood vessels. No consistent pattern of variation in mast cell numbers from the fetal end of the umbilical cord towards the placenta was seen. The total number of mast cells found in the umbilical cord was 5,200,000 (median), range 2,800,000-16,800,000 (n = 7), that is 156,000 mast cells per gram umbilical cord (median), range 48,000-267,000. Thus, the umbilical cord constitutes an adequate source of mast cells for further investigation of these cells in the newborn, e.g. for describing their functional and secretory characteristics and possible clinical relevance in relation to the development of allergic, inflammatory and immunological diseases in infancy and childhood.

  20. Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: lumican null mice.

    Directory of Open Access Journals (Sweden)

    Hongshan Liu

    Full Text Available BACKGROUND: Keratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries. Our study aims to develop alternative treatment regimens for congenital corneal diseases of genetic mutation. METHODOLOGY/PRINCIPAL FINDINGS: Human mesenchymal stem cells isolated from neonatal umbilical cords were transplanted to treat thin and cloudy corneas of lumican null mice. Transplantation of umbilical mesenchymal stem cells significantly improved corneal transparency and increased stromal thickness of lumican null mice, but human umbilical hematopoietic stem cells failed to do the same. Further studies revealed that collagen lamellae were re-organized in corneal stroma of lumican null mice after mesenchymal stem cell transplantation. Transplanted umbilical mesenchymal stem cells survived in the mouse corneal stroma for more than 3 months with little or no graft rejection. In addition, these cells assumed a keratocyte phenotype, e.g., dendritic morphology, quiescence, expression of keratocyte unique keratan sulfated keratocan and lumican, and CD34. Moreover, umbilical mesenchymal stem cell transplantation improved host keratocyte functions, which was verified by enhanced expression of keratocan and aldehyde dehydrogenase class 3A1 in lumican null mice. CONCLUSIONS/SIGNIFICANCE: Umbilical mesenchymal stem cell transplantation is a promising treatment for congenital corneal diseases involving keratocyte dysfunction. Unlike donated corneas, umbilical mesenchymal stem cells are easily isolated, expanded, stored, and can be quickly recovered from liquid nitrogen when a patient is in urgent need.

  1. Índices de resistência e pulsatilidade das artérias uterinas no primeiro e segundo trimestres de gestações normais Uterine arteries resistance and pulsatility indices at the first and second trimesters of normal pregnancies

    Directory of Open Access Journals (Sweden)

    Antonio Gadelha da Costa

    2010-06-01

    Full Text Available OBJETIVO: Determinar os índices de resistência (IR e pulsatilidade (IP nas artérias uterinas durante o primeiro e segundo trimestres de gestação. MATERIAIS E MÉTODOS: Realizamos estudo prospectivo longitudinal em 44 mulheres normais, da 8ª a 12ª e na 22ª semanas de gestação. A dopplervelocimetria foi realizada em ambas as artérias uterinas por meio do IR e do IP. Utilizamos volume de amostra de 1 a 2 mm, filtro de 50 a 70 Hz e ângulo de insonação abaixo de 60°. RESULTADOS: O IR e o IP da artéria uterina no primeiro trimestre foram maiores da 8ª a 12ª do que na 22ª semana de gestação. O IR e o IP da artéria uterina, no primeiro trimestre, com incisura foram de 0,83 ± 0,07 e 2,32 ± 0,79, e sem incisura, de 0,71 ± 0,16 e 1,61 ± 0,78, respectivamente. No segundo trimestre, o IR e o IP da artéria uterina com incisura foram de 0,59 ± 0,09 e 1,03 ± 0,32, e sem incisura, de 0,44 ± 0,09 e 0,63 ± 0,19, respectivamente. CONCLUSÃO: Estabelecemos os valores de referência do IR e do IP das artérias uterinas de gestantes normais no primeiro e segundo trimestres de gestação.OBJECTIVE: To determine uterine artery resistance index (RI and pulsatility index (PI during the first and second trimesters of pregnancy. MATERIALS AND METHODS: The authors developed a prospective longitudinal study with 44 healthy women at their 8th-12th and 22nd gestational weeks. Doppler velocimetry was utilized for evaluating RI and PI of both uterine arteries, with a sample volume of 1 to 2 mm, a 50-70 Hz filter, and an insonation angle < 60°. RESULTS: At 8th-12th gestational weeks, the uterine artery RI and PI were higher than at the 22nd gestational week. At the first trimester uterine artery RI and PI were, respectively, 0.83 ± 0.07 and 2.32 ± 0.79 with a notch, and 0.71 ± 0.16 and 1.61 ± 0.78, without a notch. At the second trimester, uterine artery RI and PI were, respectively, 0.59 ± 0.09 and 1.03 ± 0.32 with a notch, and 0.44 ± 0

  2. Histomorfometria e histoquímica da tuba uterina e do útero de ratas púberes e pré-púberes induzidas ao hipertireoidismo Histomorphometry and histochemistry of the uterine tubes and uterus of puberal and prepuberal rats induced for hyperthyroidism

    Directory of Open Access Journals (Sweden)

    T.S. Oliveira

    2005-08-01

    Full Text Available Foram estudadas a histomorfometria e a atividade secretória das tubas uterinas e do útero de 38 ratas Wistar púberes, distribuídas em quatro grupos: (1 eutireóideo em proestro-estro, (2 hipertireóideo em proestro-estro, (3 eutireóideo em metaestro-diestro e (4 hipertireóideo em metaestro-diestro. Posteriormente, foram utilizadas outras 24 ratas Wistar pré-púberes, com 12 dias de idade, distribuídas em dois grupos: (1 hipertireóideo (n=12 e (2 eutireóideo (n=12. O útero e as tubas uterinas foram colhidos para avaliação histomorfométrica e histoquímica. A altura do epitélio da ampola, tanto no proestro-estro quanto no metaestro-diestro, elevou-se com a administração de tiroxina, tornando-se semelhante à do istmo. O hipertireoidismo aumentou a secreção PAS positiva e de mucossubstâncias ácidas do infundíbulo na fase estrogênica, igualando-a à do istmo. A parede uterina apresentou-se mais espessa na fase estrogênica, resultado da ação conjunta da tiroxina no endométrio e no miométrio. A atividade secretória e a composição do colágeno uterino não diferiram entre tratamentos. Nas ratas pré-púberes, o hipertireoidismo aumentou a espessura do miométrio e da parede uterina, mas não alterou a tuba uterina. O hipertireoidismo em ratas pré-púberes induz modificações significativas somente no útero; após a maturidade sexual, as modificações ocorrem no útero e na tuba uterina em intensidade variável e dependentes da fase do ciclo estral.The histomorphometry and the secretory activity of the uterine tubes and uterus of 38 puberal Wistar rats were studied. Rats were divided in four groups: (1 euthyroid in proestrus-estrus, (2 hyperthyroid in proestrus-estrus, (3 euthyroid in metestrus-diestrus and, (4 hyperthyroid in metestrus-diestrus. In other experiment, 24 prepuberal 12-day-old Wistar rats were divided in two groups: (1 hyperthyroid and (2 euthyroid. The uterus and the uterine tubes were collected for

  3. Arteria iliaca interna transplantation to repair arteria iliacaexterna

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    @@CASE REPORT A 20-year-old man was admitted for blunt trauma to left lower abdomen and dysfunction of left lower limb for 8 h. Physical examination: skin contusion for 5 cm in diameter at the left iliac fossa, accompanied with subcutaneous extravasated blood, tenderness and rebound tenderness of left lower quadrant, no abnormality of rectum palpated by digital examination. The left lower limb was pale, paresthesia, paralysis and low skin temperature, but no pitting edema. The pulsation of the left femoral artery and dorsalis pedis artery could not be palpated. Color Doppler imaging showed no flow in lumen of the upper portion of the left external iliac artery for 5-6 cm in length. The diagnosis,was traumatic arterial occlusion of the left external iliac artery. Laparotomy was performed. Haematoma in left lower abdominal wall and retroperitoneum, partial sever of external and internal oblique muscle were found. Dissection of the common iliac artery, external and internal iliac artery showed normal pulsation of

  4. Chronic complaints after simple sutured repair for umbilical or epigastric hernias may be related to recurrence

    DEFF Research Database (Denmark)

    Westen, Mikkel; Christoffersen, Mette W; Jorgensen, Lars N;

    2014-01-01

    PURPOSE: Umbilical and epigastric hernia repairs are minor, but are commonly conducted surgical procedures. Long-term results have only been sparsely investigated. Our objective was to investigate the risk of chronic complaints after a simple sutured repair for small umbilical and epigastric...... hernias. METHODS: A retrospective cohort study with a 5-year questionnaire and clinical follow-up was conducted. Patients undergoing primary elective, open non-mesh umbilical or epigastric sutured hernia repair were included. Patients completed a structured questionnaire regarding chronic complaints...

  5. Mercury in the Umbilical Cord: Implications for Risk Assessment for Minamata Disease

    DEFF Research Database (Denmark)

    Dalgård, Christine; Grandjean, Philippe; Jørgensen, Poul Jørgen;

    1994-01-01

    in umbilical cord blood and in maternal hair. The results were compared with published values for mercury in umbilical cord tissue from 12 infants diagnosed with congenital methylmercury poisoning in Minamata, Japan. From the regression coefficients obtained in the Faroese samples, the median umbilical cord...... mercury concentration of 4.95 nmol/g dry weight in Minamata would correspond to 668 nmol/l cord blood and 114 nmol/g maternal hair. These levels agree well with other evidence of susceptibility of the fetus to increased exposure to methylmercury....

  6. Persistent Umbilical Discharge from an Omphalomesenteric Duct Cyst Containing Gastric Mucosa

    Directory of Open Access Journals (Sweden)

    Kanimozhi Tamilselvan

    2012-01-01

    Full Text Available Umbilical discharge in infancy is often attributed to infection or an umbilical granuloma. It is important to investigate if such a discharge is due to an underlying congenital abnormality because corrective surgical intervention may then be required. We present the first case of an infant with a persistent umbilical discharge from an omphalomesenteric duct cyst. The discharge was associated with periumbilical dermatitis. The dermatitis was most likely due to irritation of the skin by gastric acid produced by the ectopic gastric mucosa contained in the omphalomesenteric duct cyst. Both discharge and dermatitis resolved after surgical removal of the cyst.

  7. [Advantage of delayed umbilical cord clamping in the newborn infant].

    Science.gov (United States)

    Menget, A; Mougey, C; Thiriez, G; Riethmuller, D

    2013-09-01

    The timing of umbilical cord clamping remains controversial. Although most maternity wards use the early clamping (5-15s), randomized studies and meta-analyses have demonstrated the benefit of delayed clamping for term and preterm newborn infants over the past 10 years. Indeed, placentofetal transfusion of 20-30 ml/kg in 2-3 min improves the iron status of term infants and prevents infant hypochromic anemia. Infant anemia is a public health problem in many developing countries. For preterm newborns, placental transfusion for 45 s or milking the cord for 15 s improves cardiovascular adaptation, with better hemodynamic stability, as well as decreased intraventricular hemorrhages, need for transfusion, and late-onset sepsis. A new look at this symbolic act is needed and professionals need to be persuaded of the importance of the "wait a minute" policy for a better physiological delivery.

  8. Recurrent umbilical or epigastric hernia during and after pregnancy

    DEFF Research Database (Denmark)

    Oma, Erling; Jensen, Kristian K; Jorgensen, Lars N

    2016-01-01

    BACKGROUND: Umbilical and epigastric (umb/epi) hernia repairs are performed commonly in fertile female patients. Recent studies suggest mesh repair to be superior to suture repair; however, evidence is lacking concerning the optimal treatment of umb/epi hernias in female patients who might wish...... future pregnancies. The aim of this study was to compare the cumulative recurrence rate after mesh versus suture repair of umb/epi hernia in female patients subsequently becoming pregnant. METHODS: This retrospective nationwide cohort study included female patients who underwent primary umb/epi hernia...... repair and subsequently became pregnant between 2007 and 2013. The follow-up began at first day of pregnancy and ended May 2015. Data were obtained from the Danish Ventral Hernia Database, Medical Birth Registry, and National Patient Registry. Patients with recurrence before pregnancy were excluded...

  9. Umbilical Cord Blood Stem Cells. Who has the right word?

    Directory of Open Access Journals (Sweden)

    Gisela Laporta

    2014-12-01

    Full Text Available In this article we analyze bioethical and legal aspects related to the cryopreservation of cord blood stem cells in Argentina. To unify definitions, the concept and variety of stem cells, together with the understanding of the means to obtain and store umbilical cord blood stem cells, are provided.  Options that arise in our country, mainly analyzing the conceptual differences underlying legal body and parts by public and private biobanks, are described. Additionally, the current Argentinean legislation and circumstances arising from a resolution which INCUCAI sought to regulate private biobanks, is analyzed. This analysis leads to thoughts on the way conflicts are solved when the health and life of people are judicialized. In this particular case, the appearance of a complex new topic which gives rise to new social and healthcare scenarios, must be further understood.

  10. Strength Analysis Modelling of Flexible Umbilical Members for Marine Structures

    Directory of Open Access Journals (Sweden)

    S. Sævik

    2012-01-01

    Full Text Available This paper presents a 3-dimensional finite element formulation for predicting the behaviour of complex umbilical cross-sections exposed to loading from tension, torque, internal and external pressure including bending. Helically wound armours and tubes are treated as thin and slender beams formulated within the framework of small strains but large displacements, applying the principle of virtual displacements to obtain finite element equations. Interaction between structural elements is handled by 2- and 3-noded contact elements based on a penalty parameter formulation. The model takes into account a number of features, such as material nonlinearity, gap and friction between individual bodies, and contact with external structures and with a full 3-dimensional description. Numerical studies are presented to validate the model against another model as well as test data.

  11. Isolation of mesenchymal stem cells from equine umbilical cord blood

    DEFF Research Database (Denmark)

    Koch, Thomas Gadegaard; Heerkens, Tammy; Thomsen, Preben Dybdahl

    2007-01-01

    Background: There are no published studies on stem cells from equine cord blood although commercial storage of equine cord blood for future autologous stem cell transplantations is available. Mesenchymal stem cells (MSC) have been isolated from fresh umbilical cord blood of humans collected non......-invasively at the time of birth and from sheep cord blood collected invasively by a surgical intrauterine approach. Mesenchymal stem cells isolation percentage from frozen-thawed human cord blood is low and the future isolation percentage of MSCs from cryopreserved equine cord blood is therefore expectedly low......, for the first time, the isolation of mesenchymal-like stem cells from fresh equine cord blood and their differentiation into osteocytes, chondrocytes and adipocytes. This novel isolation of equine cord blood MSCs and their preliminary in vitro differentiation positions the horse as the ideal pre-clinical animal...

  12. Morphological aspects of buffaloes (Bubalus bubalis umbilical cord Aspectos Morfológicos do cordão umbilical de búfalos (Bubalus bubalis

    Directory of Open Access Journals (Sweden)

    Guilherme J. Ferreira

    2009-10-01

    Full Text Available Buffalo is an important livestock resource, with a great participation in agricultural systems, providing milk, meat, and work power. Umbilical cord is responsible for maternal-fetal nutrients exchange during pregnancy, and its alterations can compromise the fetal development. We investigated ten pregnant uteruses collected from cross-bread buffaloes in different stages of gestation. Pregnancy and fetal age was determined by measuring the apex sacral length and development period was calculated by previously published formula. Umbilical cords were measured for length determination. Umbilical cord vascular net and anastomosis were observed by injection of Neoprene latex. Histological sections of the umbilical cord were studied after stain with HE, picrossirius, toluidine blue, orceine, and PAS reaction. Buffaloes' umbilical cord was formed by two central arteries, an allantois duct and two peripheral veins. The artery wall was composed by large quantity of collagen, elastic fibers, fibroblasts and large number of vasa vasorum. The allantois duct was located between the arteries and presented a great number of small nourishing vessels. Small nourishing vessels should be carefully considered to avoid to be mistaken to the arterials and veins vasa vasorum. Medium length of umbilical cord from buffalos was 11.8cm (minimum of 6.8cm and maximum of 17.4cm.Búfalo é uma importante fonte de recurso nos rebanhos animais, apresentando uma grande participação na agropecuária, provendo leite, carne e força de trabalho. O Cordão umbilical é responsável pela troca de nutrientes materno-fetais durante a gestação, e suas alterações podem comprometer o desenvolvimento fetal. Nós investigamos dez úteros gravídicos de búfalos de raças cruzadas em fases diferentes de gestação. O período de gestação e a idade fetal foram determinados pelo comprimento ápice sacral, aplicando fórmulas previamente estabelecidas. Posteriormente mediu-se o

  13. Distribuição da altura uterina ao longo da gestação em uma coorte brasileira: comparação com a curva de referência do Centro Latino-Americano de Perinatologia Distribution of uterine height during pregnancy in a Brazilian cohort: comparison with the reference curve of the Centro Latino-Americano de Perinatologia

    OpenAIRE

    Maria Lúcia Rocha Oppermann; Bruce Bartholow Duncan; Sotero Serrate Mengue; José Geraldo Lopes Ramos; Suzanne Jacob Serruya; Maria Inês Schmidt

    2006-01-01

    OBJETIVOS: descrever, em gestantes do Estudo Brasileiro do Diabetes Gestacional (EBDG), a distribuição da altura uterina de acordo com a idade gestacional e validar a curva do Centro Latino-Americano de Perinatologia (CLAP), curva de referência para a predição de anormalidades do crescimento fetal. MÉTODOS: o EBDG é uma coorte de 5564 gestantes, com mais de 19 anos, seguidas até e após o parto. Entrevistas e medidas antropométricas padronizadas foram feitas no arrolamento entre a 20ª e a 28ª ...

  14. Dopplervelocimetria das artérias uterinas no primeiro trimestre de gestação: avaliação dos índices de pulsatilidade e correlação com crescimento intra-uterino restrito e perda gestacional

    OpenAIRE

    Adriana Belo Fernandes

    2006-01-01

    Muitos estudos já demonstraram o valor do doppler de artérias uterinas no segundo trimestre da gestação, apresentando-o como método de rastreamento eficiente para a identificação das pacientes de risco. Tais investigações correlacionam o aumento da resistência ao fluxo e a persistência de incisura protodiastólica nesses vasos com mais probabilidade de desenvolvimento de préeclâmpsia e crescimento intra-uterino restrito. O presente trabalho retrospectivo analisou o banco de dados da Clínica de...

  15. Dopplervelocimetria das artérias uterinas na predição de complicações em gestações de baixo risco Uterine artery doppler velocimetry for the prediction of complications in low-risk pregnancies

    Directory of Open Access Journals (Sweden)

    Fabrício da Silva Costa

    2005-06-01

    Full Text Available OBJETIVO: determinar a validade da dopplervelocimetria das artérias uterinas na predição de complicações da gestação em população de nulíparas de baixo risco. MÉTODOS: foi conduzido estudo prospectivo que incluiu 45 pacientes primigestas, sem história de doenças crônicas. A dopplervelocimetria das artérias uterinas foi realizada entre 24 e 26 semanas, com determinação do índice de resistência (IR, índice de pulsatilidade (IP, relação S/D e a presença ou ausência de incisura na onda de velocidade de fluxo. Na análise estatística foi utilizado o teste de Mann-Whitney para amostras não paramétricas e o teste exato de Fisher foi utilizado na avaliação dos parâmentros qualitativos. RESULTADOS: complicações da gravidez foram observadas em 12 pacientes, com quatro casos de pré-eclâmpsia, um caso de recém-nascido pequeno para a idade gestacional (PIG, um caso de PIG e parto pré-termo (PPT, três casos de PPT, um caso de centralização fetal e dois casos de mecônio espesso no líquido amniótico no momento da resolução da gestação. Notamos que o IR (mediana 0,56 x 0,68, IP (mediana 0,98 x 1,29 e a relação S/D (mediana 2,2 x 2,9 estavam mais elevados no exame realizado entre a 24 e a 26ª semana nas pacientes que apresentaram qualquer complicação da gestação e não mostrou diferença nos casos de pré-eclâmpsia ou PIG. A presença de incisura bilateral apresentou sensibilidade de 100 e 90%, especificidade de 60,6 e 62,5%, valor preditivo positivo (VPP de 29,4 e 42,9%, valor preditivo negativo (VPN de 100 e 95,2% para a detecção de pré-eclâmpsia ou PIG e qualquer complicação da gestação, respectivamente. A dopplervelocimetria alterada apresentou sensibilidade de 83,3 e 83,3%, especificidade de 69,7 e 69,7%, VPP de 33,3 e 50,0%, VPN de 95,8 e 92,0% para a detecção de pré-eclâmpsia ou PIG e qualquer complicação da gestação, respectivamente. CONCLUSÃO: índices de alta impedância e a presen

  16. Efecto, en un modelo murino, de dos polisacáridos sulfatados sobre la producción de citoquinas por células NK uterinas y de sangre periférica

    Directory of Open Access Journals (Sweden)

    Angela Patricia Cadavid Jaramillo

    2000-02-01

    Full Text Available

    Las células asesinas naturales (NK uterinas son una subpoblación diferente a las de sangre periférica, expresan los marcadores CD56bright y CD16- y constituyen los linfocitos más abundantes de la decidua humana (70%. Estas células juegan un papel protagónico en el aloreconocimiento del feto, en el control de la invasión del trofoblasto y promueven el crecimiento de la unidad fetoplacentaria mediante la producción del factor estimulante de colonias de granulocitos y macrófagos y del factor estimulante de colonias de monocitos (CSF-1. En los ratones transgénicos Tg2978 deficientes en células NK se presenta una reducción de hasta un 66% en su viabilidad intrauterina y una disminución del 45% en el tamaño placentario señalando la estrecha relación de estas células con la biología de la reproducción.

    De otro lado existen pruebas directas e indirectas de que las células NK podrían ser responsables en algunos casos de falla del embarazo. Diversos tratamientos para el aborto recurrente espontáneo (ARE regulan negativamente el número y la actividad de las células NK como los glicosaminoglicanes sulfatados, y en especial la heparina, que bloquean in vitro su actividad lítica, tal como lo ha demostrado nuestro grupo. En estudios  clínicos de pacientes con ARE de causa inmunológica se observa un efecto benéfico de la combinación heparina-aspirina con o sin inmunizaciones con linfocitos, por lo cual se propone como una posible terapia de esta alteración. Se ha visto además que otro polisacárido sulfatado, el fucoidan, estimula la producción del factor de crecimiento hepático y

  17. Acetylcholine secretion by motor neuron-like cells from umbilical cord mesenchymal stem cells

    Institute of Scientific and Technical Information of China (English)

    Xueyuan Liu; Dehua Li; Dong Jiang; Yan Fang

    2013-01-01

    Umbilical cord mesenchymal stem cel s were isolated by a double enzyme digestion method. The third passage of umbilical cord mesenchymal stem cel s was induced with heparin and/or basic fi-broblast growth factor. Results confirmed that cel morphology did not change after induction with basic fibroblast growth factor alone. However, neuronal morphology was visible, and microtu-bule-associated protein-2 expression and acetylcholine levels increased fol owing induction with heparin alone or heparin combined with basic fibroblast growth factor. Hb9 and choline acetyl-transferase expression was high fol owing inductive with heparin combined with basic fibroblast growth factor. Results indicate that the inductive effect of basic fibroblast growth factor alone was not obvious. Heparin combined with basic fibroblast growth factor noticeably promoted the differen-tiation of umbilical cord mesenchymal stem cel s into motor neuron-like cel s. Simultaneously, um-bilical cord mesenchymal stem cel s could secrete acetylcholine.

  18. Hypoxanthine in fetal umbilical venous blood and amniotic fluid from pregnancies complicated by rhesus isoimmunization.

    Science.gov (United States)

    Stangenberg, M; Legarth, J; Hong-Lie, C; Lingman, G; Persson, B; Rahman, F; Westgren, M

    1993-09-01

    Concentrations of hypoxanthine (HX) was determined in umbilical venous blood and amniotic fluid obtained at 74 instances in 36 rhesus immunized patients before the onset of labor. HX concentrations were related to gestational age, concentrations of hemoglobin and lactate, pH, and partial oxygen pressure in umbilical venous blood. Multiple regression analysis revealed hemoglobin concentration to be the only variable that had any explanatory power to HX in amniotic fluid. No one of the studied variables gave any significant contribution to a regression model to explain HX in umbilical venous blood. We conclude that HX levels in umbilical venous blood and in amniotic fluid from rhesus immunized patients were not associated with fetal blood gases before the onset of labor.

  19. Comparison of complication rates between umbilical and peripherally inserted central venous catheters in newborns

    NARCIS (Netherlands)

    Arnts, I.J.J.; Bullens, L.M.; Groenewoud, J.M.M.; Liem, K.D.

    2014-01-01

    OBJECTIVE: To compare the complication rates between umbilical central venous catheters and peripherally inserted central venous catheters in newborns and to investigate whether other variables might increase complication rates. DESIGN: A retrospective observational study. SETTING: A Level III neona

  20. The umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood.

    Science.gov (United States)

    Zeddou, Mustapha; Briquet, Alexandra; Relic, Biserka; Josse, Claire; Malaise, Michel G; Gothot, André; Lechanteur, Chantal; Beguin, Yves

    2010-07-01

    Many studies have drawn attention to the emerging role of MSC (mesenchymal stem cells) as a promising population supporting new clinical concepts in cellular therapy. However, the sources from which these cells can be isolated are still under discussion. Whereas BM (bone marrow) is presented as the main source of MSC, despite the invasive procedure related to this source, the possibility of isolating sufficient numbers of these cells from UCB (umbilical cord blood) remains controversial. Here, we present the results of experiments aimed at isolating MSC from UCB, BM and UCM (umbilical cord matrix) using different methods of isolation and various culture media that summarize the main procedures and criteria reported in the literature. Whereas isolation of MSC were successful from BM (10:10) and (UCM) (8:8), only one cord blood sample (1:15) gave rise to MSC using various culture media [DMEM (Dulbecco's modified Eagle's medium) +5% platelet lysate, DMEM+10% FBS (fetal bovine serum), DMEM+10% human UCB serum, MSCGM] and different isolation methods [plastic adherence of total MNC (mononuclear cells), CD3+/CD19+/CD14+/CD38+-depleted MNC and CD133+- or LNGFR+-enriched MNC]. MSC from UCM and BM were able to differentiate into adipocytes, osteocytes and hepatocytes. The expansion potential was highest for MSC from UCM. The two cell populations had CD90+/CD73+/CD105+ phenotype with the additional expression of SSEA4 and LNGFR for BM MSC. These results clearly exclude UCB from the list of MSC sources for clinical use and propose instead UCM as a rich, non-invasive and abundant source of MSC.

  1. Experimental and numeric studies of one electro-optical flexible pipe (umbilical); Estudos numericos e experimentais de um umbilical eletro-optico

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    Lepore, Paula Ferreira; Buelta Martinez, Miguel Angel [Sao Paulo Univ., SP (Brazil). Escola Politecnica

    2005-07-01

    This work had as objective to develop, to implant, to survey and to test an experimental and numerical model of structural, applicable analysis of umbilical structures. An ample study of the behavior of its constituent layers was carried through, in special of its nucleus and material constituents, when operating under different conditions of tensions and deformations. As support for this work, experimental tests for one type of electro-optic umbilical with typical transversal section had been carried through. This was made with the intention to optimize the developed numerical model. With this model of structural analysis, the project of umbilicals could highly improved, in terms of the total weight of the handle, which is one of the great problems for its use in great depths, with the maximum of efficiency and the minimum of losses, foreseeing and hindering operation imperfections that can come to occur due to extreme deformation or electric rupture of the layers, hoses or handles. (author)

  2. A PROSPECTIVE STUDY OF FACTORS INFLUENCING THE TIME OF SEPARATION OF UMBILICAL CORD

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    Lokesha

    2014-12-01

    Full Text Available : BACKGROUND: The umbilical cord usually shrivels and falls off at around 5 to 15days of life. It is important to know timing of separation, so that parents may be advised on proper cord care and ally any misconceptions about the cord separation; early discharge has increased the need for women to receive accurate, relevant information on how to care for themselves and their newborns when discharged from the hospital. Delay in separation of the umbilical cord, umbilical discharge, odor, or granuloma causes concern and source of immense anxiety for parents, the interval between delivery and umbilical cord separation varies worldwide, this study is undertaken to determine time of separation and factors influencing the separation. OBJECTIVES: To determine time of separation of umbilical cord and factors influencing it. METHODS: SETTINGS: Babies admitted at a tertiary hospital, selected by purposive sampling technique. For each recruited baby, data is obtained about mother's parity, mode of delivery, gestational age, birth weight, and gender of baby, method of resuscitation, phototherapy, IV antibiotics, and cord blood TSH values, time of umbilical cord separation after birth. Newborns whose umbilical cord shriveled off during the stay in the hospital information were obtained directly, and a self-addressed postcard was given to parents of newborns whose umbilical cord was intact at time of discharge. Parents would be advised to note and write the date of fall of umbilical cord on post card and mail it. RESULTS: Cord separation time ranges from 3 to 11 days, with mean separation of 5.62 ± 2.37 days, it is one to two days earlier as compared to previous studies, seventy nine (79 of hundred and ten (110 separated between 5-7 days (71%, one baby had separation at 11days, babies who received antibiotics had statistically significant delay in separation time of umbilical, neonates received antibiotics had mean separation time (6 ± 2.4 days as compared

  3. Double suicide genes selectively kill human umbilical vein endothelial cells

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    Liu Lunxu

    2011-02-01

    Full Text Available Abstract Background To construct a recombinant adenovirus containing CDglyTK double suicide genes and evaluate the killing effect of the double suicide genes driven by kinase domain insert containing receptor (KDR promoter on human umbilical vein endothelial cells. Methods Human KDR promoter, Escherichia coli (E. coli cytosine deaminase (CD gene and the herpes simplex virus-thymidine kinase (TK gene were cloned using polymerase chain reaction (PCR. Plasmid pKDR-CDglyTK was constructed with the KDR promoter and CDglyTK genes. A recombinant adenoviral plasmid AdKDR-CDglyTK was then constructed and transfected into 293 packaging cells to grow and harvest adenoviruses. KDR-expressing human umbilical vein endothelial cells (ECV304 and KDR-negative liver cancer cell line (HepG2 were infected with the recombinant adenoviruses at different multiplicity of infection (MOI. The infection rate was measured by green fluorescent protein (GFP expression. The infected cells were cultured in culture media containing different concentrations of prodrugs ganciclovir (GCV and/or 5-fluorocytosine (5-FC. The killing effects were measured using two different methods, i.e. annexin V-FITC staining and terminal transferase-mediated dUTP nick end-labeling (TUNEL staining. Results Recombinant adenoviruses AdKDR-CDglyTK were successfully constructed and they infected ECV304 and HepG2 cells efficiently. The infection rate was dependent on MOI of recombinant adenoviruses. ECV304 cells infected with AdKDR-CDglyTK were highly sensitive to GCV and 5-FC. The cell survival rate was dependent on both the concentration of the prodrugs and the MOI of recombinant adenoviruses. In contrast, there were no killing effects in the HepG2 cells. The combination of two prodrugs was much more effective in killing ECV304 cells than GCV or 5-FC alone. The growth of transgenic ECV304 cells was suppressed in the presence of prodrugs. Conclusion AdKDR-CDglyTK/double prodrog system may be a useful

  4. Distribuição da altura uterina ao longo da gestação em uma coorte brasileira: comparação com a curva de referência do Centro Latino-Americano de Perinatologia Distribution of uterine height during pregnancy in a Brazilian cohort: comparison with the reference curve of the Centro Latino-Americano de Perinatologia

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    Maria Lúcia Rocha Oppermann

    2006-09-01

    Full Text Available OBJETIVOS: descrever, em gestantes do Estudo Brasileiro do Diabetes Gestacional (EBDG, a distribuição da altura uterina de acordo com a idade gestacional e validar a curva do Centro Latino-Americano de Perinatologia (CLAP, curva de referência para a predição de anormalidades do crescimento fetal. MÉTODOS: o EBDG é uma coorte de 5564 gestantes, com mais de 19 anos, seguidas até e após o parto. Entrevistas e medidas antropométricas padronizadas foram feitas no arrolamento entre a 20ª e a 28ª semana. Os prontuários foram revisados segundo protocolo padronizado, abrangendo os períodos de pré-natal e parto. As análises referem-se a 3539 gestantes com datação da gravidez confirmada por ultra-sonografia. Determinamos as propriedades diagnósticas dos percentis 10 e 90 de altura uterina de ambas as curvas (EBDG e CLAP como indicadores de anormalidade no peso neonatal. RESULTADOS: as medidas de altura uterina no EBDG foram maiores que as do CLAP em todas as semanas de gestação (1 a 4 cm e 2 a 6 cm, respectivamente, nos percentis 10 e 90. O percentil 10 do CLAP identificou como pequenas as medidas uterinas de 0,3 a 1,7% das gestantes brasileiras, ao passo que o percentil 90 classificou como grandes as medidas uterinas de 42 a 57% das brasileiras. A sensibilidade do percentil 10 do CLAP para predizer recém-nascidos pequenos para a idade gestacional variou de 0,8 a 6% e a especificidade do percentil 90 para predizer grandes para a idade gestacional, de 46 a 61%. CONCLUSÕES: a curva de referência do CLAP não reflete o padrão de crescimento uterino das gestantes brasileiras, limitando sua capacidade de identificar anormalidades de crescimento fetal, especialmente a restrição de crescimento.PURPOSE: to describe, in participants of the Brazilian Study of Gestational Diabetes (EBDG, the percentile distribution of uterine height by gestational age and to validate the use of percentiles of the chart derived by the "Centro Latino

  5. Associação entre a Incisura Diastólica das Artérias Uterinas e a Histologia do Leito Placentário em Grávidas com Pré-eclâmpsia Association between Diastolic Notch of Uterine Artery and the Histology of the Placental Bed in Pregnant Women with Preeclampsia

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    Regina Amélia Lopes Pessoa de Aguiar

    2001-08-01

    Full Text Available Objetivo: avaliar a associação entre a presença da incisura diastólica nas artérias uterinas maternas e as alterações histopatológicas dos vasos útero-placentários. Métodos: estudo transversal incluindo 144 pacientes com gestação única interrompida por via abdominal entre a 27ª e a 41ª semana. Destas, 84 gestações estavam associadas à pré-eclâmpsia e 60 não apresentaram intercorrências clínicas. Neste grupo realizou-se dopplerfluxometria de ambas as artérias uterinas e biópsia do leito placentário. Resultados: das 144 pacientes, 88 (61% tiveram o fragmento da biópsia considerado representativo do leito placentário. A incisura diastólica estava presente em 40 (70% dos casos de alterações fisiológicas inadequadas e ausente em 28 (90% dos casos de alterações fisiológicas presentes (p=0,05. A dopplerfluxometria apresentou sensibilidade de 70%, especificidade de 90% e valores preditivos positivo e negativo de 44 e 97%, respectivamente. A associação entre a presença de incisura diastólica bilateral das artérias uterinas e arteriopatia decidual também foi significativa (dos 25 casos de arteriopatia decidual a incisura estava presente em 24, p=0,05. A sensibilidade da dopplerfluxometria foi de 96%, especificidade de 70% e valores preditivos positivo e negativo de 26 e 99%, respectivamente, ao passo que para a arteriolosclerose a dopplerfluxometria apresentou sensibilidade de 80%, especificidade de 55% e valores preditivos positivo e negativo de 17 e 96%, respectivamente. Conclusões: a incisura diastólica nas artérias uterinas maternas é indicador seguro de vasculopatia no leito placentário. A adequada invasão trofoblástica do leito placentário, revelada por histologia típica de alterações fisiológicas, resulta na ausência de incisura diastólica bilateral das artérias uterinas maternas.Purpose: to evaluate the association between the presence of diastolic notch in the maternal uterine arteries, and

  6. Generation, Expansion, and Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) Derived From the Umbilical Cords of Newborns.

    Science.gov (United States)

    Song, Richard S; Carroll, Jeanne M; Acevedo, Lisette; Wu, Dongmei; Liu, Yang; Snyder, Evan Y

    2014-05-16

    The umbilical cord is tissue that is normally discarded after the delivery of the infant, but it has been shown to be a rich source of stem cells from the cord blood, Wharton's jelly, and umbilical endothelial cells. Patient-specific human induced pluripotent stem cells (hiPSCs) reprogrammed from patient specific human umbilical vein endothelial cells in the neonatal intensive care unit (NICU) population (specifically, premature neonates) have not been shown in the literature. This unit describes a protocol for the generation and expansion of hiPSCs originating from umbilical cords collected from patients in the NICU.

  7. Pregnancy hypertension and umbilical cord blood lead levels

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    Rabinowitz, M.; Bellinger, D.; Leviton, A. (Children' s Hospital, Boston, MA (USA)); Needleman, H. (Children' s Hospital, Pittsburgh, PA (USA)); Schoenbaum, S. (Harvard Community Health Plan, Brookline Village, MA (USA))

    Pregnancy hypertension, blood pressure during labor, and the umbilical cord blood lead concentration were assessed in 3,851 women for whom additional demographic, medical, and personal information was available. Lead levels correlated with both systolic and diastolic blood pressure during labor. The incidence of clinically defined pregnancy hypertension, nearly 11% overall, increased with lead level. A series of multivariate models of pregnancy hypertension and of systolic blood pressure as a function of maternal age, parity, hematocrit, ponderal index, race, season, and diabetes were improved by including lead as a predictor variable. These other risk factors are not affected by the lead term. The relative risk for pregnancy hypertension doubles when lead increases from 2 to 15 {mu}g/dl. The effect is statistically strong, with a magnitude of about 3 mm for a 10 {mu}g/dl range, about the same magnitude associated with diabetes. At these observed levels (mean blood lead = 6.0 {mu}g/dl, SD = 3.3, range 0 > 35), not currently recognized as overtly toxic, lead has a small but demonstrable association with pregnancy hypertension and blood pressure at the time of delivery, but not with pre-eclampsia nor toxemia. Although this association is not likely to influence the clinical management of hypertension, it indicates that lead at typical contemporary urban levels, does effect multiple physiological functions.

  8. DERMATO FIBROSARCOMA PROTUBERANS IN UMBILICAL REGION: A CASE REPORT

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    Mythili Devi

    2015-01-01

    Full Text Available Dermatofibrosarcoma protuberans is a rare fibroblastic mesenchymal skin tumor with low - grade malignancy and occasional distant metastasis. The tumour accounts for less than 0.001% of all malignancies. Most cases involve the trunk, extremities, scalp, and neck. In rare cases, the genital urinary system may be affected. Diagnostic tools include computed tomography and magnetic resonance imaging. The standard treatment of wide - margin surgical excision with a clear margin of 3 - 4 cm may be problematic in large tumors or in some areas of the body, as a radical excision may produce unacceptable cosmetic, structural, or functional results. An un resected or positive margin should be treated with adjuvant radiotherapy to help prevent recurrence. Chemotherapy plays a limited role in treating this disease. This article describes a 55years male with mass in umbilical region who underwent wide local excision and rhombhoid flap transfer to cover the defect. Later patient sent for adjuvant radiotherapy, patient was tumour free at 6 months follow up.

  9. Enterococcus faecalis internalization in human umbilical vein endothelial cells (HUVEC).

    Science.gov (United States)

    Millán, Diana; Chiriboga, Carlos; Patarroyo, Manuel A; Fontanilla, Marta R

    2013-04-01

    Initial Enterococcus faecalis-endothelial cell molecular interactions which lead to enterococci associating in the host endothelial tissue, colonizing it and proliferating there can be assessed using in vitro models. Cultured human umbilical vein endothelial cells (HUVEC) have been used to study other Gram-positive bacteria-cell interactions; however, few studies have been aimed at establishing the relationship of E. faecalis with endothelial cells. The aggregation substance (AS) family of adhesins represents an E. faecalis virulence factor which has been implicated in endocarditis severity and bacterial persistence. The Asc10 protein (a member of this family) promotes bacterium-bacterium aggregation and bacterium-host cell binding. Evaluating Asc10 role in bacterial internalization by cultured enterocytes has shown that this adhesin facilitates E. faecalis endocytosis by HT-29 cells. A few eukaryotic cell structural components, such as cytoskeletal proteins, have been involved in E. faecalis entry into cell-lines; it is thus relevant to determine whether Asc10, as well as microtubules and actin microfilaments, play a role in E. faecalis internalization by cultured endothelial cells. The role of Asc10 and cytoskeleton proteins in E. faecalis ability to enter HUVEC was assessed in the present study, as well as cell apoptosis induction by enterococcal internalization by HUVEC; the data indicated increased cell apoptosis and that cytoskeleton components were partially involved in E. faecalis entry to endothelial cells, thereby suggesting that E. faecalis Asc10 protein would not be a critical factor for bacterial entry to cultured HUVEC.

  10. [A Nude Mouse Model for Human Umbilical Cord Blood Transplantation

    Science.gov (United States)

    Lan, Jiongcai; Liu, Hongyu; Chen, Qiang; Yang, Chongli; Zhang, Zhimei

    2000-03-01

    To evaluate the hematopoietic potentiality and the migration and homing routine of separated as well as cryopreserved umbilical cord blood hematopoietic cells, the BALB/cnu(+) mice were used to establish a murine model. This can prepare for the clinical transplantation and the establishment of a large-scale cord blood bank. The result indicated that the hydroxyethyl starch (HES) sedimentation and DMSO step-by-step cryopreservation procedure resulted in only less losses of hematopoietic progenitor cells and also unharmful to the hematopietic potentiality. We can found evidence for successful transplantation in each mouse which received (1.0 - 2.0) x 10(7) separated or cryopresered hematopoietic cells from cord blood, which lasted for about fifty days. The results demonstrated that (1) HES sedimentation and DMSO cryopreservation procedure can keep the hematopoietic potentiality of cord blood, and so can be used to clinical transplantation or establishment of a cord blood bank; (2) Rich hematopoietic stem cells in human cord blood can cross the xenogenetic barriers and successfully engraft mice; (3) The hematopoietic cells migrated among bone marrow, liver, spleen, lung and kidney in the mice and homed to bone marrow by the end. Cryopreservation may influence the adhesion molecule on the hematopoietic cells and the homing behaviour, but not influence their hematopoietic potentiality.

  11. Improving engraftment and immune reconstitution in umbilical cord blood transplantation

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    Robert eDanby

    2014-02-01

    Full Text Available Umbilical cord blood (UCB is an important source of haematopoietic stem cells (HSC for allogeneic transplantation when HLA-matched sibling and unrelated donors (MUD are unavailable. Although the overall survival rates of UCB transplantation are comparable to the results with MUD, UCB transplants are associated with slow engraftment, delayed immune reconstitution, and increased opportunistic infections. While this may be a consequence of the lower cell dose in UCB grafts, it also reflects the relative immaturity of cellular immunity within cord blood. Furthermore, the limited number of cells and the non-availability of donor lymphocyte infusions (DLI currently prevent the use of post-transplant cellular immunotherapy to boost donor-derived immunity to treat infection, mixed chimerism and disease relapse. Therefore, to further develop UCB transplantation, many strategies to enhance engraftment and immune reconstitution are currently under investigation. This review summarises our current understanding of engraftment and immune recovery following UCB transplantation and why this differs from allogeneic transplants using other sources of HSC. It also provides an comprehensive overview of the promising techniques being used to improve myeloid and lymphoid recovery, including expansion, homing, and delivery of UCB HSC; combined use of UCB with third party donors; isolation and expansion of NK cells, pathogen specific T cells, and regulatory T cells; methods to protect and/or improve thymopoiesis. As many of these strategies are now in clinical trials, it is anticipated that UCB transplantation will continue to advance, further expanding our understanding of UCB biology and HSC transplantation.

  12. Embolização das artérias uterinas com partículas de PVA-PVAC esférico como preparo para posterior ressecção cirúrgica de miomas

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    Juraci Ghiaroni

    2013-10-01

    Full Text Available OBJETIVO: avaliar a utilização de uma nova partícula de polivinil álcool e polivinil acetato (PVA-PVAc esférica, para embolização das artérias uterinas, em pacientes portadoras de mioma, com indicação cirúrgica. MÉTODOS: doze pacientes foram submetidas à embolização de miomas uterinos com partículas de PVA-PVAc. Três a nove meses depois, realizou-se uma laparotomia com miomectomia. Analisaram-se os seguintes parâmetros: volume do útero e do maior mioma; concentrações do hormônio folículo estimulante e de hemoglobina; sangramento menstrual (número de dias e de absorventes utilizados, sinais e sintomas antes do tratamento, após a embolização e após a miomectomia. RESULTADOS: a média de idade foi 37 anos e a média do volume uterino, previamente ao tratamento, de 939,3cc. Três anos após a embolização, observou-se diminuição do volume uterino (p=0,0005. Houve melhora na concentração de hemoglobina (p= 0,0004, com elevação após a embolização, sem variação subsequente à miomectomia. Não ocorreu variação significante do hormônio folículo estimulante, (p=0,17. Não foi constatado nenhum caso de falência ovariana, mas uma das pacientes apresentou atrofia de endométrio. Duas pacientes engravidaram, com bons indicadores obstétricos. Quanto aos sinais e sintomas, houve melhora após a embolização, que se manteve após a miomectomia. CONCLUSÃO: a embolização arterial com partículas de PVA-PVAc esférico mostrou-se promissora no preparo para uma intervenção cirúrgica com retirada dos miomas, pois, associou-se à redução do volume uterino, à diminuição do sangramento operatório e tornou possível a utilização de incisões menores, aumentando a chance de preservação do útero.

  13. Desempenho reprodutivo de fêmeas suínas inseminadas pela técnica intra-uterina ou tradicional Reproductive performance of swine females inseminated by intrauterine or traditional technique

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    Djane Dallanora

    2004-08-01

    Full Text Available O desempenho reprodutivo de fêmeas suínas foi avaliado com o objetivo de comparar duas técnicas de inseminação. Foram inseminadas, em delineamento inteiramente casualizado, 608 fêmeas com ordem de parto de dois a quatro, em dois tratamentos: inseminação intra-uterina com 1,5 bilhão de espermatozóides em 60 mL e inseminação tradicional, com 3 bilhões em 90 mL. Foi possível introduzir o cateter intra-uterino em 97,4% das fêmeas e houve sangramento em 9,5%, as quais apresentaram retorno ao estro superior (pThe reproductive performance of sows was evaluated aiming at the comparison of two insemination techniques. In a completely randomized design, 608 females of 2-4 parities were inseminated in two treatments: intrauterine with 1.5x10(9 spermatozoa/60 mL or traditional insemination with 3x10(9 spermatozoa/90 mL. It was possible to insert the intrauterine catheter in 97.4% of females and bleeding was observed in 9.5%, which had a higher probability to repeat estrus (p<0.05. The percentage of semen backflow volume, during two hours after insemination, was significantly higher (p<0.05 in intrauterine insemination than traditional, whereas sperm backflow percentage was similar. The sperm backflow percentage did not influence the farrowing rate and the litter size. There was no difference in the return to estrus rate (3.6%; 4.3%, pregnancy rate at 21 days post-insemination (99.5%; 97.2%, adjusted farrowing rate (94.9%; 94.3% and average litter size (11.6; 11.8 piglets between treatments, respectively. The intrauterine insemination ensures a reproductive performance similar to traditional, but with a lower sperm number.

  14. Umbilical hernia and pregnancy. A case presentation. Hernia umbilical y embarazo. Presentación de un caso.

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    Doris González Díaz

    Full Text Available A case of a 30 year-old black, female patient, born in Angola, Africa with past history of multiple miscarriages is presented. She stated that the last pregnancy she had had abdominal pain, as well as some other less common discomfort. A great umbilical hernia defect was detected which affected the pregnant uterus and other abdominal viscera. It was necessary to admit the patient into the hospital during the last 10 weeks of pregnancy until the cesarean surgery and the hernia reparation was performed. The mother and infant developed satisfactorily and were discharged from the hospital. They were followed up in consultations to which they never assisted. The low frequency of occurrence of this association which was corroborated by means of national as well as international bibliographical revision. This led us to prepare this report.
    Se describe el caso de una paciente de raza negra, de 30 años de edad, natura de Angola, con antecedentes de múltiples abortos espontáneos, que durante su último embarazo había presentado dolores abdominales frecuentes, además de otras molestias poco comunes. Se detectó un gran defecto herniario umbilical, que afectaba el útero grávido y otras vísceras abdominales. Para llevar el embarazo a término fue necesario ingresar a la paciente durante las últimas 10 semanas de embarazo, hasta la realización de la cesárea y la cirugía de reparación de la hernia. Tanto la madre como el niño evolucionaron satisfactoriamente, siendo dados de alta con citación para consultas de seguimiento posterior a la cual no acudieron nunca. La escasa frecuencia con que se presenta esta asociación, lo cual fue corroborado mediante la revisión de la literatura nacional e internacional, es lo que condujo a la realización del presente informe.

  15. Pertussis seroprevalence in adults, post-partum women and umbilical cord blood.

    Science.gov (United States)

    Fallo, Aurelia; Manonelles, Gabriela; Hozbor, Daniela; Lara, Claudia; Huespe, Miguel; Mazzeo, Silvina; Canle, Oscar; Galas, Marcelo; López, Eduardo

    2014-08-01

    Pertussis is a vaccine-preventable disease that affects people of all ages. Young adults who have lost their immunity to pertussis are the major source of infection in infants. Given the steady increase of pertussis cases, new prevention strategies are required. Objective. To assess pertussis seroprevalence in adult blood donors, post-partum women, and umbilical cords. Metod. Measurement of total titers of anti-Bordetella spp. (Bordetella) antibodies using an enzyme-linked immunosorbent assay. Serum samples from 103 donors, 101 post-partum women and 100 umbilical cords were analyzed. Titers <80 were considered of low impact against the disease. The assessment included transplacental transfer of antibodies and the umbilical cord/maternal ratio of antibody titers. Results. Donors mean age was: 28 ± 6 years old. Mediananti-Bordetella titers: 320; interquartile range (IQR):160-320; 10% had titers <80. Post-partum women mean age was: 26 ± 6 years old. Median anti-Bordetella titers:160 (IQR:80-320), with titers significantly lower than in female donors (p= 0.00002). Titers <80 were found in 30% of post-partum women. Median anti-Bordetella titers in umbilical cords: 160 (IQR: 80-160). Titers <80 were more frequently found in umbilical cords than in mothers (44% versus 30%, p= 0.04). Transplacental transfer was 0.83. Umbilical cord titers were equal to maternal titers in 54% of cases, lower in 37%, and higher only in 8%. Conclusion. Titers of anti-Bordetella antibodies in post-partum women were significantly lower than in female blood donors. Titers <80 were found in 30% of post-partum women and 44% of umbilical cords. These data may account for the high rates of pertussis in young infants who have not yet completed their vaccination schedule.

  16. Ultrasound-guided rectus sheath block in children with umbilical hernia: Case series

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    Abdul Hamid Alsaeed

    2013-01-01

    Full Text Available Background: Umbilical hernia repair, a common day-case surgery procedure in children, is associated with a significant postoperative pain. The most popular peripheral nerve blocks used in umbilical hernia repair are rectus sheath infiltration and caudal block. The rectus sheath block may offer improved pain relief following umbilical hernia repair with no undesired effects such as lower limb motor weakness or urinary retention seen with caudal block which might delay discharge from the hospital. Ultrasound guidance of peripheral nerve blocks has reduced the number of complications and improved the quality of blocks.The aim of this case series is to assess the post rectus sheath block pain relief in pediatric patients coming for umbilical surgery. Methods: Twenty two (22 children (age range: 1.5-8 years scheduled for umbilical hernia repair were included in the study. Following the induction of general anesthesia, the ultrasonographic anatomy of the umbilical region was studied with a 5-16 MHz 50 mm linear probe. An ultrasound-guided posterior rectus sheath block of both rectus abdominis muscles (RMs was performed (total of 44 punctures. An in-plain technique using Stimuplex A insulated facet tip needle 22G 50mm. Surgical conditions, intraoperative hemodynamic parameters, and postoperative analgesia by means of the modified CHEOPS scale were evaluated. Results: ultrasonograghic visualization of the posterior sheath was possible in all patients. The ultrasound guided rectus sheath blockade provided sufficient analgesia in all children with no need for additional analgesia except for one patient who postoperatively required morphine 0.1 mg/kg intravenously. There were no complications. Conclusions: Ultrasound guidance enables performances of an effective rectus sheath block for umbilical hernia. Use of the Stimuplex A insulated facet tip needle 22G 50mm provides easy, less traumatic skin and rectus muscle penetration and satisfactory needle

  17. Ultrasonic characteristics and clinical significance of umbilical cord blood flow in acute fetal distress

    Institute of Scientific and Technical Information of China (English)

    Wei Dai; Yin Xu; Xing-Wei Ma; Li Zhang; Ming-Juan Zhu

    2016-01-01

    Objective: To study ultrasonic characteristics of umbilical cord blood flow in acute fetal distress and its correlation with umbilical artery blood gas parameters, oxidative stress parameters, neonatal brain injury and myocardial injury. Methods: The pregnant women delivered in Department of Obstetrics of our hospital were chosen during the period from May 2012 to August 2015. The pregnant women with acute fetal distress were included in the distress group, and the healthy pregnant women with no acute fetal distress were included in the control group. The resistance index (RI), pulsatility index (PI) and systolic/diastolic (S/D) ratio of umbilical artery were measured at 24–30 weeks, 31–36 weeks and 37–41 weeks of pregnancy. After delivery, umbilical artery blood was taken for analysis of blood gas and determination of oxidative stress parameters. The venous blood of newborns was taken to measure the myocardial injury and brain injury parameters. Results: At 24–30 weeks, 31–36 weeks and 37–41 weeks of pregnancy, RI, S/D and PI in pregnant women of distress group were significantly higher than those in control group. The pH, contents of arterial partial pressure of oxygen, vitamin C, vitamin E, superoxide dis-mutase and glutathione peroxidase in umbilical artery blood in pregnant women of distress group was significantly lower than those in control group and negatively correlated with the umbilical artery RI, PI and S/D. The contents of partial pressure of carbon dioxide in artery, lactic acid and malondialdehyde in pregnant women of distress group were significantly higher than those in control group and positively correlated with the umbilical artery RI, PI and S/D. The contents of lactate dehydrogenase, hydroxybutyrate dehydrogenase, creatine kinase, creatine kinase-MB, S100B, neuron-specific enolase, creatine kinase-BB and Tau in newborns' venous blood in distress group were significantly higher than those in control group and positively correlated

  18. Ultrasonic character istics and clinical significance of umbilical cord blood flow in acute fetal distress

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    Wei Dai, Yin Xu

    2016-11-01

    Full Text Available Objective: To study ultrasonic characteristics of umbilical cord blood flow in acute fetal distress and its correlation with umbilical artery blood gas parameters, oxidative stress parameters, neonatal brain injury and myocardial injury. Methods: The pregnant women delivered in Department of Obstetrics of our hospital were chosen during the period from May 2012 to August 2015. The pregnant women with acute fetal distress were included in the distress group, and the healthy pregnant women with no acute fetal distress were included in the control group. The resistance index (RI, pulsatility index (PI and systolic/diastolic (S/D ratio of umbilical artery were measured at 24–30 weeks, 31–36 weeks and 37–41 weeks of pregnancy. After delivery, umbilical artery blood was taken for analysis of blood gas and determination of oxidative stress parameters. The venous blood of newborns was taken to measure the myocardial injury and brain injury parameters. Results: At 24–30 weeks, 31–36 weeks and 37–41 weeks of pregnancy, RI, S/D and PI in pregnant women of distress group were significantly higher than those in control group. The pH, contents of arterial partial pressure of oxygen, vitamin C, vitamin E, superoxide dismutase and glutathione peroxidase in umbilical artery blood in pregnant women of distress group was significantly lower than those in control group and negatively correlated with the umbilical artery RI, PI and S/D. The contents of partial pressure of carbon dioxide in artery, lactic acid and malondialdehyde in pregnant women of distress group were significantly higher than those in control group and positively correlated with the umbilical artery RI, PI and S/D. The contents of lactate dehydrogenase, hydroxybutyrate dehydrogenase, creatine kinase, creatine kinase-MB, S100B, neuron-specific enolase, creatine kinase-BB and Tau in newborns' venous blood in distress group were significantly higher than those in control group and

  19. A altura uterina é capaz de diagnosticar os desvios do volume de líquido amniótico? Is uterine height able to diagnose amniotic fluid volume deviations?

    Directory of Open Access Journals (Sweden)

    Djacyr Magna Cabral Freire

    2013-02-01

    Full Text Available OBJETIVO: Avaliar o desempenho de uma curva de altura uterina (AU quanto à capacidade de rastrear desvios do volume de líquido amniótico, utilizando uma curva brasileira de índice de líquido amniótico (ILA como padrão-ouro. MÉTODOS: O presente estudo representa um corte transversal no qual foram incluídas 753 gestantes em acompanhamento pré-natal na rede pública de João Pessoa (PB no período de março a outubro de 2006 e que tiveram um exame de ultrassonografia (US de rotina agendado para depois da 26ª semana de idade gestacional. Foram excluídos os casos com diagnóstico de gestação gemelar, óbito fetal intrauterino e malformações fetais maiores. Além de informações sociodemográficas, foram coletados também os valores da AU medida de forma padronizada, os valores do peso fetal estimado, do ILA e a idade gestacional pelo exame de US. A capacidade da curva de AU em predizer os desvios do volume de líquido amniótico foi avaliada tendo uma curva brasileira de ILA em função da idade gestacional como padrão-ouro. Para isso, foram estimados a sensibilidade, especificidade e valores preditivos positivo e negativo para diferentes pontos de corte. RESULTADOS: A medida da AU identificou 10,5% das mulheres como AU baixa e possivelmente associada ao oligoâmnio, e 25,2% como AU alta e possivelmente associada ao polidrâmnio. Utilizando uma curva brasileira de referência para ILA, a AU foi capaz de predizer pobremente a ocorrência de oligoâmnio (sensibilidade variando entre 37 a 28% e de forma razoável a ocorrência de polidrâmnio (sensibilidade variando entre 88 a 69%. CONCLUSÃO: A medida da altura uterina mostrou um desempenho ruim para predizer oligoâmnio e um desempenho razoável para predizer polidrâmnio. Sua utilização para essa finalidade só se justifica, portanto, em situações nas quais o exame ultrassonográfico não esteja fácil e rotineiramente disponível, a fim de ajudar na priorização dos casos que

  20. In Vitro Vasoactive Effects of Levobupivacaine and Ropivacaine on the Isolated Human Umbilical Artery and Vein

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    Alper Kılıçaslan

    2011-06-01

    Full Text Available Objective: In this in vitro study, we investigated the vasoactive effects of levobupivacaine and ropivacaine on vascular smooth muscle derived from human umbilical arteries and veins.Material and Methods: The strips were mounted in tissue baths at 37°C continuously gassed with 5% CO2 in oxygen for isometric recording of contractile activity on a polygraph. The endothelium of some tissues was mechanically removed to assess the influence of the endothelium on contractility. The strips were precontracted with serotonin (10-6 M 5-HT; n=7. After obtaining the maximal contraction, responses obtained by adding levobupivacaine and ropivacaine (10-9-10-4 M; n=7 cumulatively were recorded. Contractions were expressed as the (% of 5HT maximal response percentage of 5 HT’s maximal response.Results: Both levobupivacaine and ropivacaine induce a concentration-dependent contraction in the smooth muscle cells of umbilical arteries and veins. Maximum contractile response (Emax of levobupivacaine (79.2±2.5, 71.1±2.6 was higher than ropivacaine (68.4±2, 36.2±2.8 on both umbilical arteries and veins. There were no statistically significant differences between contraction responses of endothelium-intact and endothelium-denuded tissues. Conclusion: The results suggest that, in high concentrations, levobupivacaine and ropivacaine may affect umbilical blood flow by contracting the umbilical artery and vein, thus reducing fetal blood flow.

  1. Design of the Core Stage Inter-Tank Umbilical {CSITU) Compliance Mechanism

    Science.gov (United States)

    Smith, Kurt R.

    2013-01-01

    Project Goals: a) Design the compliance mechanism for the CSITU system to a 30% level -3D models completed in Pro/Engineer -Relevant design analysis b) Must meet all system requirements and establish basis for proceeding with detailed design. Tasks to be completed: A design that meets requirements for the 30% design review, 01/16/2013. Umbilical arms provide commodities to the launch vehicle prior to T-0. Commodities can range anywhere from hydraulics, pneumatics, cryogenic, electrical, ECS, etc ... Umbilicals commonly employ truss structures to deliver commodities to vehicle. Common configurations include: -Tilt-up -Swing Arm -Hose Drape -Drop Arm Umbilical arms will be mounted to Mobile Launch Platform. SLS currently has 9 T-0 umbilical arms. The compliance refers to the ability of the umbilical to adjust to minor changes in vehicle location. The compliance mechanism refers to the mechanism on the ground support equipment {GSE) that compensates for these changes. For the CSITU, these minor changes, or vehicle excursions, can be up to +4 in. Excursions refer to movements of the vehicle caused by wind loads and thermal expansion. It is ideal to have significant vertical compliance so a passive secondary release mechanism may be implemented.

  2. Umbilical hernia rupture with evisceration of omentum from massive ascites: a case report

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    Neary Paul C

    2011-05-01

    Full Text Available Abstract Introduction The incidence of hernias is increased in patients with alcoholic liver disease with ascites. To the best of our knowledge, this is the first report of an acute rise in intra-abdominal pressure from straining for stool as the cause of a ruptured umbilical hernia. Case presentation An 81-year-old Caucasian man with a history of alcoholic liver disease presented to our emergency department with an erythematous umbilical hernia and clear, yellow discharge from the umbilicus. On straining for stool, after initial clinical assessment, our patient noted a gush of fluid and evisceration of omentum from the umbilical hernia. An urgent laparotomy was performed with excision of the umbilicus and devitalized omentum. Conclusion We report the case of a patient with a history of alcoholic liver disease with ascites. Ascites causes a chronic increase in intra-abdominal pressure. A sudden increase in intra-abdominal pressure, such as coughing, vomiting, gastroscopy or, as in this case, straining for stool can cause rupture of an umbilical hernia. The presence of discoloration, ulceration or a rapid increase in size of the umbilical hernia signals impending rupture and should prompt the physician to reduce the intra-abdominal pressure.

  3. Umbilical Hernia in Peritoneal Dialysis Patients: Surgical Treatment and Risk Factors.

    Science.gov (United States)

    Banshodani, Masataka; Kawanishi, Hideki; Moriishi, Misaki; Shintaku, Sadanori; Ago, Rika; Hashimoto, Shinji; Nishihara, Masahiro; Tsuchiya, Shinichiro

    2015-12-01

    No previous reports have focused on surgical treatments and risk factors of umbilical hernia alone in peritoneal dialysis (PD) patients. Herein, we evaluated the treatments and risk factors. A total of 411 PD patients were enrolled. Of the 15 patients with umbilical hernia (3.6%), six underwent hernioplasty. There was no recurrence in five patients treated with tension-free hernioplasty. The mean PD vintage after onset of hernia in the hernioplasty group tended to be longer than that in the non-hernioplasty group. An incarcerated hernia occurred in one non-hernioplasty patient. Although the incidence was significantly higher among women (P = 0.02), female sex was not a risk factor for umbilical hernia (P = 0.08). Our findings suggest that umbilical hernias should be repaired for continuing PD. Furthermore, there were no significant risk factors for umbilical hernia in PD patients. Future studies with larger sample groups are required to elucidate these risk factors.

  4. A novel technique of midline mesh repair for umbilical hernia associated with diastasis recti.

    Science.gov (United States)

    Matei, Ovidio-Angel; Runkel, Norbert

    2014-03-01

    Mesh repair has evolved as the gold standard for umbilical hernias. Surgical reconstruction of umbilical hernias in association with diastasis recti has not been discussed in the recent literature. We describe a novel surgical technique of midline mesh repair for this combined lesion. This is a retrospective review of 44 consecutive patients. Forty-four patients underwent surgery for umbilical hernia with diastasis recti between January 2010 and August 2012. All excess skin, subcutaneous tissue, and distracted midline (linea alba) were excised supraumbilically and paraumbilically according to preoperative marking. Surgical repair began with a midline running suture of the posterior rectal sheath. A light prolene mesh was placed retromuscularly into this sheath and anchored in all directions with a distance of about 5 cm from the midline using U-shaped stitches. The anterior rectal fascia was closed with a continuous suture. All information was obtained from the hospital records. The median operative time was 93.3 minutes (28 to 219 minutes). The median length of postoperative hospital stay was 5.9 days (3 to 12 days). There was no major complication. One minimal umbilical skin necrosis was observed. Analgesic medication was required in all patients. Opiods were added in 84.0% of patients on day 1, in 75.0% on day 3, and in 2.3% on day 7. Our novel technique of sublay mesh repair for combined umbilical hernia and diastasis recti is safe and effectively restores the abdominal midline.

  5. Umbilical hernia rupture with evisceration of omentum from massive ascites: a case report

    LENUS (Irish Health Repository)

    Good, Daniel W

    2011-05-03

    Abstract Introduction The incidence of hernias is increased in patients with alcoholic liver disease with ascites. To the best of our knowledge, this is the first report of an acute rise in intra-abdominal pressure from straining for stool as the cause of a ruptured umbilical hernia. Case presentation An 81-year-old Caucasian man with a history of alcoholic liver disease presented to our emergency department with an erythematous umbilical hernia and clear, yellow discharge from the umbilicus. On straining for stool, after initial clinical assessment, our patient noted a gush of fluid and evisceration of omentum from the umbilical hernia. An urgent laparotomy was performed with excision of the umbilicus and devitalized omentum. Conclusion We report the case of a patient with a history of alcoholic liver disease with ascites. Ascites causes a chronic increase in intra-abdominal pressure. A sudden increase in intra-abdominal pressure, such as coughing, vomiting, gastroscopy or, as in this case, straining for stool can cause rupture of an umbilical hernia. The presence of discoloration, ulceration or a rapid increase in size of the umbilical hernia signals impending rupture and should prompt the physician to reduce the intra-abdominal pressure.

  6. Umbilical hernia in adults: day case local anaesthetic repair.

    Directory of Open Access Journals (Sweden)

    Menon V

    2003-01-01

    Full Text Available INTRODUCTION: The waiting times for elective surgery of Umbilical hernia (UH in adults are unacceptably long in some cases. During this period, irreducibility and strangulation are possible. We operate on adult patients under local anaesthesia (LA as day cases to avoid this delay and describe our experience in this paper. AIMS: The aims of our study were to look at the age and sex distribution, body weight, type and amount of local anaesthetic used, morbidity, admission and readmission rates, and waiting times of adult patients operated on for UH under LA. MATERIALS AND METHODS: It was a retrospective study covering a 4 year period from July 1996 to June 2000 including all adult patients undergoing the above procedure under the care of a single consultant general surgeon. A standard Mayo repair using non absorbable material was used without a mesh or a drain. RESULTS: 32 patients with UH were operated on under LA, 23 males and 9 females with a median age of 51 years (range 20 to 86 years. The body weight ranged from 63 to 120 (median 87 kg. The average duration of the procedure was 30 (range 22-40 minutes. Sedation was needed in 4 patients. Two patients developed wound infections, one superficial and one deep. There was no mortality. The median period of follow-up was 24 (range 4-48 months and there was no recurrence. The median waiting time for the operation was 6 weeks. CONCLUSIONS: Day case local anaesthetic repair of UH in adults seems to be safe and feasible with an acceptable morbidity. Suture repair in the right patient has excellent results and the waiting times are acceptable.

  7. Umbilical cord blood banks. Ethical aspects. Public versus private banks.

    Science.gov (United States)

    Aznar Lucea, Justo

    2012-01-01

    The creation of umbilical cord blood (UCB) banks raises interesting medical, social, economic and ethical issues. This paper reviews the ethical problems specifically. In this respect, it evaluates: a) whether there are advantages to the use of UCB compared to bone marrow, b) whether or not it is ethical to create UCB banks, c) whether their creation is ethically acceptable in terms of their clinical usefulness or d) the use made of them for therapeutic purposes, and finally e) whether their creation is ethically justified from a cost/profitability point of view. We focus primarily on evaluating the ethical controversy between public and private banks, particularly on whether it is ethical to bank autologous blood in private UCB banks, on the basis of its limited possibilities for use by the cord blood donor. We can conclude that, from an ethical point of view, autologous blood banks have limited acceptance among specialised researchers, scientific societies and other public institutions. Therefore, we believe that it is ethically more acceptable to support the creation of public UCB banks for medical and social reasons and, above all, based on the principle of justice and human solidarity. Nevertheless, there is no definitive ethical argument why a couple, according to their autonomy and freedom, cannot bank their child's UCB in a private bank. An equally acceptable solution could be the creation of mixed banks, such as that proposed by the Virgin Health Bank or like the Spanish system where autologous samples can be stored in public banks but with the proviso that if at any time the stored sample is required by any person other than the donor, it would have to be given to them.

  8. Isolation of mesenchymal stem cells from equine umbilical cord blood

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    Thomsen Preben D

    2007-05-01

    Full Text Available Abstract Background There are no published studies on stem cells from equine cord blood although commercial storage of equine cord blood for future autologous stem cell transplantations is available. Mesenchymal stem cells (MSC have been isolated from fresh umbilical cord blood of humans collected non-invasively at the time of birth and from sheep cord blood collected invasively by a surgical intrauterine approach. Mesenchymal stem cells isolation percentage from frozen-thawed human cord blood is low and the future isolation percentage of MSCs from cryopreserved equine cord blood is therefore expectedly low. The hypothesis of this study was that equine MSCs could be isolated from fresh whole equine cord blood. Results Cord blood was collected from 7 foals immediately after foaling. The mononuclear cell fraction was isolated by Ficoll density centrifugation and cultured in a DMEM low glucose based media at 38.5°C in humidified atmosphere containing 5% CO2. In 4 out of 7 samples colonies with MSC morphology were observed. Cellular morphology varied between monolayers of elongated spindle-shaped cells to layered cell clusters of cuboidal cells with shorter cytoplasmic extensions. Positive Alizarin Red and von Kossa staining as well as significant calcium deposition and alkaline phosphatase activity confirmed osteogenesis. Histology and positive Safranin O staining of matrix glycosaminoglycans illustrated chondrogenesis. Oil Red O staining of lipid droplets confirmed adipogenesis. Conclusion We here report, for the first time, the isolation of mesenchymal-like stem cells from fresh equine cord blood and their differentiation into osteocytes, chondrocytes and adipocytes. This novel isolation of equine cord blood MSCs and their preliminary in vitro differentiation positions the horse as the ideal pre-clinical animal model for proof-of-principle studies of cord blood derived MSCs.

  9. Tratamento de hérnia umbilical em bovinos

    Directory of Open Access Journals (Sweden)

    Luiz Antônio Franco da Silva

    2012-02-01

    Full Text Available Bovinos jovens são frequentemente acometidos por hérnias umbilicais. Neste trabalho, avaliou-se a ocorrência e estabeleceu-se o tratamento cirúrgico para hérnias umbilicais em bovinos jovens, empregando 78 bezerros distribuídos em seis grupos. Em GI e GIV, na laparorrafia, utilizou-se sutura jaquetão; em GII e GV, jaquetão modificado e, em GIII e GVI, sutura separada simples com pontos de relaxamento. Em GI, GII e GIII utilizou-se fio de algodão e, em GIV, GV e GVI, de náilon. Dados não paramétricos, envolvendo a recuperação dos animais e sua independência ou associações com o padrão de sutura foram analisados pelo teste do Qui-quadrado e Exato de Fisher, fazendo-se uso do programa computacional Statistical Analysis System, a 5% (p < 0,05. Os demais resultados foram analisados descritivamente. A ocorrência de hérnia umbilical em bovinos foi expressiva e a herniorrafia, empregando-se fio de algodão, apresentou maiores complicações pós-operatórias; porém a maioria dos animais recuperou-se. O fio e o padrão de sutura, manejo pós-operatório, resposta individual e o tamanho do anel herniário influenciam na reabilitação dos animais e na redução das complicações pós-operatórias.

  10. Optimización en el uso del colgajo de segunda perforante intercostal de la arteria mamaria interna Optimizing the use of the second intercostal perforator flap of the internal mammary artery

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    D. Sicilia Castro

    2012-06-01

    Full Text Available El colgajo en isla basado en perforantes de la arteria mamaria interna (colgajo IMAP se emplea de manera reciente como técnica reconstructiva en cabeza y cuello. El objetivo de esta revisión es corroborar las posibilidades del arco de rotación de dicho colgajo cuando se realiza una amplia disección de su pedículo vascular. Presentamos 4 pacientes de edades comprendidas entre 46 y 75 años, todos ellos varones, con defectos faríngeos parciales, en los que empleamos un colgajo pediculado basado en la segunda perforante de la arteria mamaria interna para reconstrucción del defecto faríngeo. El tamaño medio del defecto a cubrir fue de 3,2 cm (desviación estándar +/- 1,5 cm en sentido horizontal y 4,5 cm (desviación estándar +/- 2,2 cm en sentido vertical. En todos los casos se disecó un colgajo en isla con un tamaño medio de 6 X 8 cm. La longitud media del pedículo fue de 5,5 cm (desviación estándar +/- 1,51 cm. En todos los casos fue posible sellar el defecto faríngeo sin necesidad de resecar costilla o de incorporar parte de la arteria mamaria interna correspondiente. El colgajo IMAP es un colgajo rápido de realizar que permite la reconstrucción de defectos faríngeos parciales de la región anterior del cuello y hasta la base de la lengua sin necesidad de resección costal o incorporación parcial de los vasos mamarios.The island flap based on perforators of the internal mammary artery (IMAP flap is recently used in reconstruction of head and neck defects. The aim of this review is to verify the possibilities of the arc of rotation of the flap when it's necessary to carry out an extensive dissection of the vascular pedicle. We present reconstruction of partial pharyngeal defects in 4 patients, aged between 46 and 75 years and all men, using a pedicle flap based on the second perforator of the internal mammary artery. The average size of the defect was 3.2 cm (SD +/- 1.5 cm horizontally and 4.5 cm (SD +/- 2.2 cm vertically. In

  11. Doppler de las arterias pulmonares fetales posterior al uso de betametasona para la maduración pulmonar (Fetal lung arteries Doppler after to use of betamethasone for lung maturation

    Directory of Open Access Journals (Sweden)

    Keibis Jiménez Castillejo

    2014-06-01

    Full Text Available Resumen (español El objetivo de la investigación fue determinar las modificaciones del Doppler de las arterias pulmonares fetales posterior al uso de betametasona para la maduración pulmonar. Se realizó una investigación de tipo explicativa, prospectiva y longitudinal con un diseño cuasi-experimental y una muestra no probabilística intencional de 106 pacientes que acudieron a la consulta Pre-natal de Alto Riesgo del Hospital Central “Dr. Urquinaona". Una vez seleccionadas las pacientes se les administró inyecciones intramusculares de betametasona (12 mg/día por dos días consecutivos. Se realizaron las mediciones de índice de pulsatilidad, índice de resistencia y relación sistólico / diastólica de las arterias pulmonares fetales. Se observó disminución significativa de los valores promedio del índice de pulsatilidad en la segunda medición comparado con la medición inicial (p < 0,05. Sin embargo, el promedio de la tercera medición no mostró diferencia significativas con los valores iniciales (p = ns. El índice de resistencia disminuyó en la segunda medición para luego aumentar en la tercera medición comparado con el valor inicial (p < 0,05 para las dos mediciones. El valor promedio de la relación sistólico / diastólica presentó disminución significativa durante la segunda medición para luego presentar un aumento significativo al momento de la tercera medición comparado con el valor inicial (p < 0,05 para las dos mediciones. Se concluye que el uso de betametasona para la inducción de la maduración pulmonar produce modificaciones en las mediciones Doppler de las arterias pulmonares fetales. Abstract (english The objective of research was to determine Doppler modifications of fetal pulmonary arteries after use of betamethasone for lung maturation. An explicative, prospective and longitudinal research was done with a quasi-experimental design and an intentional non-probabilistic sample of 106 patients who assisted

  12. Embolización selectiva de la arteria carótida externa en el manejo de pacientes con tumoraciones benignas en la cavidad nasal y la cara, primeras experiencias en el Hospital México

    Directory of Open Access Journals (Sweden)

    José Luis Solano- Villarroel

    2007-01-01

    Full Text Available Justificación: El angiofibroma juvenil nasofaríngeo es uno de los tumores benignos de la cavidad nasal más comunes en los adolescentes, el cual causa epistaxis recurrente, obstrucción nasal, rinorrea y otras manifestaciones clínicas. Los hemangiomas faciales son tumoraciones benignas muy frecuentes en la infancia, y secundariamente al tumor los pacientes pueden presentar deformidades faciales e inclusive sangrados intermitentes. En la actualidad, la embolización de la arteria carótida externa está siendo más utilizada en el manejo de estos pacientes, ya que es un procedimiento mínimamente invasivo y produce una evolución clínica más favorable en los pacientes; también se ha descrito una menor pérdida sanguínea durante el procedimiento quirúrgico y en el postoperatorio, con disminución de la mortalidad. Además, proporciona al paciente una recuperación más pronta y acorta la estancia hospitalaria. Objetivo: Describir las primeras experiencias con la embolización de la arteria carótida externa en pacientes con angiofibroma juvenil nasofaringeo y hemangiomas faciales, en el Hospital México. Resultados: Cuando se hizo la embolización prequirúrgica de los angiofibromas juveniles nasofaringeos, la resección del tumor en pacientes cursó sin ninguna complicación. Además, los pacientes no tuvieron sangrado durante el postoperatorio inmediato. Tras la embolización de las pacientes con hemangiomas se documenta mejoría clínica, disminuyendo la lesión macroscópica en la cara y los sangrados secundarios al hemangioma (en un caso. En ambas enfermedades la recuperación de los pacientes fue muy satisfactoria, sin presentarse ninguna complicación y con una estancia hospitalaria muy corta. Conclusión: Desde hace varios años la embolización prequirúrgica ha sido utilizada en el extranjero como coadyuvante en el manejo de diversas condiciones. Actualmente, está siendo implementada en el medio para el manejo de diferentes

  13. Incidencia de cateterismo umbilical en la provincia. holguin (2004 - 2007: 1ª parte

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    Odalys Leyva González

    2008-01-01

    Full Text Available Aborda el uso casi generalizado del cateterismo umbilical en neonatos graves, lo que hace que Cuba alcance la tasa mas alta de morbilidad por Hipertensión Portal pre-hepática pediátrica en el mundo, secundaria a la trombosis venosa portal post-cateterismo. Se realiza un estudio epidemiológico para conocer el número de neonatos que han requerido cateterismo umbilical como base a la implantación del programa de pesquizaje y diagnóstico precoz que permita la caracterización de la población afectada. Se hace un estudio descriptivo, revisando registros epidemiológicos de unidades de neonatología de la provincia. Un total de 666 pacientes en los tres años de estudio requirieron cateterismo umbilical, siendo la principal causa hipoxia al nacer.

  14. Umbilical cord mesenchymal stem cell transplantation for the treatment of Duchenne muscular dystrophy

    Institute of Scientific and Technical Information of China (English)

    Xiaofeng Yang; Yanxiang Wu; Xinping Liu; Yifeng Xu; Naiwu Lü; Yibin Zhang; Hongmei Wang; Xin Lü; Jiping Cui; Jinxu Zhou; Hong Shan

    2011-01-01

    Due to their relative abundance, stable biological properties and excellent reproductive activity,umbilical cord mesenchymal stem cells have previously been utilized for the treatment of Duchenne muscular dystrophy, which is a muscular atrophy disease. Three patients who were clinically and pathologically diagnosed with Duchenne muscular dystrophy were transplanted with umbilical cord mesenchymal stem cells by intravenous infusion, in combination with multi-point intramuscular injection. They were followed up for 12 months after cell transplantation. Results showed that clinical symptoms significantly improved, daily living activity and muscle strength were enhanced,the sero-enzyme, electromyogram, and MRI scans showed improvement, and dystrophin was expressed in the muscle cell membrane. Hematoxylin-eosin staining of a muscle biopsy revealed that muscle fibers were well arranged, fibrous degeneration was alleviated, and fat infiltration was improved. These pieces of evidence suggest that umbilical cord mesenchymal stem cell transplantation can be considered as a new regimen for Duchenne muscular dystrophy.

  15. Incarceration of a sessile uterine fibroid in an umbilical hernia during pregnancy.

    Science.gov (United States)

    Seims, A D; Lube, M W

    2009-06-01

    On rare occasions, uterine fibroids complicate pregnancy. More commonly, fibroids exert a mass effect that either prevents implantation of an egg or becomes problematic as a fetus grows. Less frequently, pregnancies are affected by fibroid herniation through a fascial defect. Several publications describing herniation of pedunculated fibroids exist, two of which were in umbilical hernia sacs. There is, to our knowledge, only one publication describing the presence of a sessile uterine fibroid in an umbilical hernia. This case report adds to the literature by describing a 34-year-old primigravid woman with an umbilical hernia that contained a sessile uterine fibroid and provides parameters that can be used in the initial evaluation of a pregnant woman with an abdominal wall hernia.

  16. Laparoscopic umbilical hernia repair in a cirrhotic patient with a peritoneovenous shunt.

    Science.gov (United States)

    Umemura, Akira; Suto, Takayuki; Sasaki, Akira; Fujita, Tomohiro; Endo, Fumitaka; Wakabayashi, Go

    2015-05-01

    A 62-year-old Japanese woman who had developed massive cirrhotic ascites was referred to our hospital for a peritoneovenous shunt implant. However, CT examination revealed an umbilical hernia that had not been observed before the peritoneovenous shunt was implanted. We decided to perform laparoscopic umbilical hernia repair to keep carbon dioxide from flowing backward into the central circulatory system. We first clamped the catheter and set the upper limit of the pneumoperitoneum pressure to 6 mmHg. The central venous pressure was also measured simultaneously. Mesh was then applied over the hernia and fixed by the double-crown technique. Finally, 1000-mL physiological saline was infused into the abdominal cavity while the pneumoperitoneum was slowly released. In this case, we safely performed laparoscopic umbilical hernia repair while making some alterations, specifically catheter clamping, reducing pneumoperitoneum pressure, monitoring central venous pressure, and infusing physiological saline.

  17. Abnormal systemic venous connection possibly associated with a persistent right umbilical vein; a case report

    Directory of Open Access Journals (Sweden)

    Smevik Bjarne

    2004-04-01

    Full Text Available Abstract Background Abnormal venous connections involving a persistent right umbilical vein are rare. In a minority of cases the liver is entirely bypassed and the condition is associated with multiple congenital malformations. Case presentation The described case illustrates a systemic venous drainage that was severely abnormal in a newborn girl with a truncus arteriosus type II congenital heart defect. Injection of contrast medium through the umbilical vein catheter revealed a very peculiar venous connection that passed anterio-laterally through the right hemithorax before crossing in an oblique fashion towards the superior vena cava. Conclusions This venous drainage may be the result of a persistent right umbilical vein connecting with the superior vena cava.

  18. FASCIA LATA AS A SOURCE OF RECONSTRUCTION IN THE LAPAROSCOPIC REPAIR OF UMBILICAL HERNIAS

    Directory of Open Access Journals (Sweden)

    Dhamotharan

    2015-11-01

    Full Text Available AIMS AND OBJECTIVES: The aim of this study was to evaluate the versatility of tensor fascia lata flap for laparoscopic reconstruction of umbilical hernias. MATERIALS AND METHODS: In this study a total of 24 patients with defects over umbilical region were included. Reconstruction was performed using patients’ fascia lata. Patients were evaluated in terms of viability of the tissue and donor site morbidity, followed up for a period of 3 years. RESULTS: All the defects got effectively and adequately repaired using the autologous fascia lata. All the patients were followed up for an average period of 3 years. Donor site morbidity was minimal. CONCLUSION: It was concluded that the autologous fascia lata is a versatile, reliable, easy, and less time consuming procedure for the coverage of umbilical wall hernias via laparoscopy.

  19. A nationwide study on readmission, morbidity, and mortality after umbilical and epigastric hernia repair

    DEFF Research Database (Denmark)

    Bisgaard, T; Kehlet, H; Bay-Nielsen, M;

    2011-01-01

    , complications and mortality occurred in 4.1% (open 3.7%; laparoscopic 8.2%) and 0.1% (open 0.1%; laparoscopic 0.4%), respectively. CONCLUSION: This first prospective nationwide study on elective umbilical and epigastric hernia repair found low morbidity and mortality but a high readmission rate mostly because......BACKGROUND: Repair for umbilical and epigastric hernia is a minor and common surgical procedure. Early outcomes are not well documented. METHODS: All patients =18 years operated on for umbilical or epigastric hernia in Denmark during a 2-year period (2005-2006) were analysed according to hospital...... stay, risk of readmission, complications, and mortality  1 day. Readmissions occurred in 5.3% of cases (open 4.9%; laparoscopic 10.5%). In the majority of patients readmissions were due to wound-related problems (haematoma, bleeding and/or infection) (46%), seroma (19%), or pain (7%). At 30 days...

  20. Ex Vivo Expansion or Manipulation of Stem Cells to Improve Outcome of Umbilical Cord Blood Transplantation.

    Science.gov (United States)

    Horwitz, Mitchell E

    2016-02-01

    The outcome of umbilical cord blood transplantation for adult patients with hematologic malignancies now rivals that of matched unrelated donor transplantation. However, delayed hematopoietic and immunologic recovery remains a source of significant morbidity and mortality. Multiple strategies are now being studied to overcome these limitations. One strategy involves ex vivo expansion of the umbilical cord blood unit prior to transplantation. A second strategy involves exposure of the umbilical cord blood graft to compounds aimed at improving homing and engraftment following transplantation. Such a strategy may also address the problem of slow hematopoietic recovery as well as the increased risk of graft failure. Many of these strategies are now being tested in late phase multi-center clinical trials. If proven cost-effective and efficacious, they may alter the landscape of donor options for allogeneic stem cell transplantation.

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  12. Asociación de los indicadores antropométricos y de composición corporal en la predicción de la resistencia a la insulina en pacientes con enfermedad de las arterias coronarias

    Directory of Open Access Journals (Sweden)

    Larissa Pessoa Vila Nova

    Full Text Available Introducción: en los últimos años la importancia de identificar la resistencia a la insulina (RI en pacientes con enfermedades cardiovasculares isquémicas viene siendo debatida. Métodos alternativos, como los indicadores antropométricos y de composición corporal, han sido señalados como una buena opción y contribuyen para identificar anomalías metabólicas y prevenir complicaciones. Objetivo: asociar indicadores antropométricos y de composición corporal como predictores de la resistencia a la insulina (RI en pacientes con enfermedad de las arterias coronarias. Métodos: estudio transversal realizado en el hospital de referencia cardiológica de Pernambuco, en el periodo de junio a septiembre de 2014, con pacientes adultos y ancianos hospitalizados, de ambos sexos. Se verificaron los siguientes parámetros: estilo de vida, la presencia del síndrome metabólico (SM y otras comorbilidades. Se analizó la RI por el cálculo del HOMA-IR. Los pacientes se sometieron a la impedancia bioeléctrica (BIA y a las verificaciones antropométricas. Resultados: la muestra fue constituida por 75 pacientes con edad media de 63,75 ± 12,43 años, con un 64% de ancianos. Se encontró el diagnóstico de SM en el 65,3% de los pacientes, el 81,3% de sedentarios y el 37,4% con exceso de peso. Se diagnosticó la RI en el 28% de los pacientes. Se observó correlación entre el HOMA-IR y el diámetro abdominal sagital (DAS (r = 0,476; p = 0,016, el índice de masa corporal (r = 0,233; p = 0,040 y el porcentual de grasa corporal (r = 0,276; p = 0,016. Conclusión: el DAS fue el indicador antropométrico que presentó mejor correlación con la RI en pacientes con enfermedad de las arterias coronarias hospitalizados.

  13. Evaluation of three high abundance protein depletion kits for umbilical cord serum proteomics

    Directory of Open Access Journals (Sweden)

    Nie Jing

    2011-05-01

    Full Text Available Abstract Background High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been tested and evaluated in adult serum/plasma, while the depletion efficiency on umbilical cord serum/plasma had not been clarified. Structural differences between some adult and fetal proteins (such as albumin make it likely that depletion approaches for adult and umbilical cord serum/plasma will be variable. Therefore, the primary purposes of the present study are to investigate the efficiencies of several commonly-used commercial kits during high abundance protein depletion from umbilical cord serum and to determine which kit yields the most effective and reproducible results for further proteomics research on umbilical cord serum. Results The immunoaffinity based kits (PROTIA-Sigma and 5185-Agilent displayed higher depletion efficiency than the immobilized dye based kit (PROTBA-Sigma in umbilical cord serum samples. Both the PROTIA-Sigma and 5185-Agilent kit maintained high depletion efficiency when used three consecutive times. Depletion by the PROTIA-Sigma Kit improved 2DE gel quality by reducing smeared bands produced by the presence of high abundance proteins and increasing the intensity of other protein spots. During image analysis using the identical detection parameters, 411 ± 18 spots were detected in crude serum gels, while 757 ± 43 spots were detected in depleted serum gels. Eight spots unique to depleted serum gels were identified by MALDI- TOF/TOF MS, seven of which were low abundance proteins. Conclusions The immunoaffinity based kits exceeded the immobilized dye based kit in high abundance protein depletion of umbilical cord serum samples and dramatically improved 2DE gel quality for detection of trace biomarkers.

  14. A Comparative Study of Blood Culture Sampling from Umbilical Catheter Line versus Peripheral Site

    Directory of Open Access Journals (Sweden)

    Abdolkarim Hamedi

    2010-08-01

    Full Text Available Neonatal sepsis is an important cause of death and morbidity in newborns and is diagnosed by isolation of organism in blood culture. In several reports,reliablity of blood cultures were done from umbi lical catheters,have been demonstrated. The objective of the present study was to determine,wether an inde welling umbilical catheter, could be an alternative site for blood culture. In a prospective study over 6 months during 2006,141 paired blood cultures from 134 infant,were done simultaneously from peripheral site and umbilical catheter (mostly U. V. C,during the first four days of life. Majority of these infants were preterm and admitted to NICU for special care. these infants had indwelling umbilical line and had indication of sepsis workup. A total of 141 pairs of blood cultures were obtained from 134 infants. In 16 infants blood culture pairs were positive for one organism in both peripheral vein and umbilical site. 71. 6% of total cultures (n=11pairs were negative in boths site. A total of 22 pairs were positive in one site only,with 5 positive from peripheral vein only and the other 17 from umblical site. Two pairs were positve in boths site with two different organism. In over all 16 infant (11%of blood were considered to be contaminated. Contamination rate were 2. 4% and 9. 2% for peripheral and umbilical catheter site. Contamination rate increased after 48 hours of age in umbilical catheter. The result showed that after 2 days contamination rate for blood culture taken from catheter line increased and specifity decreased. We recommended that blood culture via umblical catheter in first 2 days in sick neonates with indwelling catheter can be a alternate site of blood culture sampelling.

  15. Intestinal Perforation in Obstructed Umbilical Hernia due to Wedged Plum Seed

    Directory of Open Access Journals (Sweden)

    Rahul Gupta

    2016-05-01

    Full Text Available The foreign body ingestion is a rare cause of gastrointestinal perforation in children and is typically seen with sharp foreign bodies or button batteries. Herein, we report an 11-month old male baby who presented with obstructed umbilical hernia. Abdominal radiograph showed dilated small bowel loops, while ultrasonography and CT scan suggested presence of a foreign body. Laparotomy revealed obstructed umbilical hernia with a plum seed being stuck in the terminal ileum causing intestinal perforation. Resection and anastomosis of intestine was performed.

  16. Incarceration of umbilical hernia: a rare complication of large volume paracentesis.

    Science.gov (United States)

    Khodarahmi, Iman; Shahid, Muhammad Usman; Contractor, Sohail

    2015-09-01

    We present two cases of umbilical hernia incarceration following large volume paracentesis (LVP) in patients with cirrhotic ascites. Both patients became symptomatic within 48 hours after the LVP. Although being rare, given the significantly higher mortality rate of cirrhotic patients undergoing emergent herniorrhaphy, this complication of LVP is potentially serious. Therefore, it is recommended that patients be examined closely for the presence of umbilical hernias before removal of ascitic fluid and an attempt should be made for external reduction of easily reducible hernias, if a hernia is present.

  17. Characterization of Adherent Nonhematopoietic Cells Derived from Human Umbilical Cord Blood

    Institute of Scientific and Technical Information of China (English)

    安小惠; 蔡国平

    2003-01-01

    To confirm and characterize the adherent fibroblast-like progenitors in human umbilical cord blood, we isolated mononuclear cells from human umbilical cord blood by Ficoll-Hypaque.Two main morphologically different kinds of cells were formed by culturing the cells in collagen-coated 24-well plastic dishes and flasks.One type was the adherent fibroblast-like cells, while the other was loosely adherent clonally expanded round cells.Our experiments demonstrate that the adherent fibroblast-like cells possess multilineage potential, including the ability to differentiate into endothelial-like cells and to express the mesenchymal cell marker.

  18. Double-layer mesh hernioplasty for repairing umbilical hernias in 10 goats*

    OpenAIRE

    2011-01-01

    Umbilical hernias in goats are uncommon and can vary in their etiology and management. Hernioplasty can be done by closing the abdominal wall with a horizontal mattress pattern using absorbable sutures. However, larger defects (hernial ring size >3 cm) generally require the use of prosthetic materials that allow for a tension-free repair. In this study, 10 young female goats with umbilical hernias and hernial ring sizes ranging from 7-10 cm in width were treated using a double-layer polypr...

  19. Effect of syncytiotrophoblast microvillous membrane treatment on gene expression in human umbilical vein endothelial cells

    DEFF Research Database (Denmark)

    Høgh, Mette; Tannetta, D; Sargent, I;

    2006-01-01

    directly causes the endothelial cell dysfunction of pre-eclampsia. This study investigates the effect of STBM on endothelial cell gene expression. Design Human umbilical vein endothelial cells were cultured in the presence and absence of STBM. At specified time points, total RNA was purified from...... the umbilical cords. Methods Gene expression was screened by Affymetrix GeneChips and confirmed with real-time polymerase chain reaction or enzyme-linked immunosorbent assay. Main outcome measures Fold changes in gene expression levels between treated and control cultures were calculated from the microarray...

  20. Umbilical Nodule with Cyclical Bleeding: A Case Report and Literature Review of Atypical Endometriosis

    Science.gov (United States)

    de Freitas, Cláudia V. Marques; Câmara, Sara Filipa Camacho; Vieira, José Joaquim Nunes

    2016-01-01

    Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. It affects 3 to 10 percent of women of reproductive age. Umbilical endometriosis is rare, with an estimated incidence of 0.5–1.0% among all cases of endometriosis, and is usually secondary to prior laparoscopic surgery involving the umbilicus. In this report, we described a case of umbilical endometriosis treated with surgical resection and highlight the great importance of medical history compared to complementary diagnostic tests that can be sometimes inconclusive. PMID:27747115

  1. Umbilical Nodule with Cyclical Bleeding: A Case Report and Literature Review of Atypical Endometriosis

    Directory of Open Access Journals (Sweden)

    Marlene Teixeira Andrade

    2016-01-01

    Full Text Available Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. It affects 3 to 10 percent of women of reproductive age. Umbilical endometriosis is rare, with an estimated incidence of 0.5–1.0% among all cases of endometriosis, and is usually secondary to prior laparoscopic surgery involving the umbilicus. In this report, we described a case of umbilical endometriosis treated with surgical resection and highlight the great importance of medical history compared to complementary diagnostic tests that can be sometimes inconclusive.

  2. On the Link between Umbilic Geodesics and Soliton Solutions of Nonlinear PDEs

    OpenAIRE

    1995-01-01

    In this paper we describe a new class of soliton solutions, called umbilic solitons, for certain nonlinear integrable PDES. These umbilic solitons have the property that as the space variable x tends to infinity, the solution tends to a periodic wave, and as x tends to minus infinity, it tends to a phase shifted wave of the same shape. The equations admitting solutions in this new class include the Dym equation and equations in its hierarchy. The methods used to find and analyse these solutio...

  3. Aspiração manual intrauterina no tratamento do abortamento incompleto até 12 semanas gestacionais: uma alternativa à curetagem uterina Manual vacuum aspiration uterine treatment of incomplete abortion to 12 gestational weeks: an alternative to curettage

    Directory of Open Access Journals (Sweden)

    Marcio Pedroso Saciloto

    2011-10-01

    Full Text Available OBJETIVO: Analisar a eficácia e a ocorrência de complicações, além do tempo de permanência hospitalar e as perdas sanguíneas. MÉTODOS: Trinta pacientes foram selecionadas, alternada e consecutivamente, em um dos grupos (15 no Grupo Curetagem e 15 no Grupo de Aspiração manual intrauterina. As variáveis analisadas foram: eficácia do método, ocorrência de complicações, tempo pré-procedimento, tempo de execução do procedimento, tempo pós-procedimento e tempo total de permanência hospitalar, além de hematócrito e hemoglobina, medidas antes e após o procedimento. As pacientes foram avaliadas clinicamente 10 a 14 dias após o procedimento. Para a análise estatística, foram aplicados testes paramétricos e não-paramétricos e o nível de significância admitido foi de p>0,05. RESULTADOS: Ambos os métodos foram eficazes e não foi registrada nenhuma complicação. As perdas sanguíneas foram semelhantes e o tempo de permanência hospitalar foi significativamente menor no Grupo de Aspiração Manual Intrauterina (p=0,03. CONCLUSÃO: a aspiração manual intrauterina é tão eficaz e segura quanto à curetagem uterina, com a vantagem de necessitar menor tempo de permanência hospitalar, o que aumenta a resolutividade do método, melhorando a qualidade da assistência a essas pacientes.PURPOSE: To analyze the effectiveness and occurrence of complications, in addition to hospitalization time and blood losses. METHODS: Thirty patients were assigned alternatively and consecutively to one of two groups (15 to the Curettage Group and 15 to the Manual Vacuum Aspiration Group. The following variables were analyzed: effectiveness of the method, occurrence of complications, time before the procedure, time of execution of the procedure, time after the procedure, and total time of hospital permanence, in addition to hematocrit and hemoglobin, which were measured before and after the procedure. Patients were evaluated clinically 10 to 14

  4. Transfusão intra-uterina em fetos afetados pela doença hemolítica perinatal grave: um estudo descritivo Intrauterine transfusion in fetuses affected by severe perinatal hemolytic disease: a descriptive study

    Directory of Open Access Journals (Sweden)

    Dorival Antônio Vitorello

    1998-04-01

    Full Text Available Objetivo: analisar 54 transfusões intravasculares intra-uterinas (TIVs, ressaltando complicações do procedimento e morbimortalidade perinatal. Material e Métodos: fetos submetidos a TIVs na Clínica Materno-Fetal e Maternidade Carmela Dutra (Florianópolis, SC, entre janeiro de 1992 e agosto de 1997, foram incluídos no estudo. As características das gestantes, dados relativos ao procedimento e ao recém-nascido foram tabulados para análise e apresentados de forma descritiva, utilizando-se percentagem, média, desvio padrão, mediana, variação e risco relativo (RR com intervalo de confiança de 95% (IC conforme apropriado. Resultados: foram realizadas 50 TIVs e quatro ex-sangüíneo transfusões em 21 fetos. Houve quatro óbitos (20%, três dos quais (75% ocorridos em fetos hidrópicos. A idade gestacional média quando da primeira transfusão foi de 29,1 semanas. A concentração média de hemoglobina foi de 5,69 mg/dl. A taxa de mortalidade decorrente do procedimento foi de 7,4%. A idade gestacional média ao nascimento foi 33,9 semanas e o peso médio foi 2.437 gramas. Sessenta e cinco por cento dos recém-nascidos receberam ex-sangüíneo transfusão complementar. Conclusão: a taxa de mortalidade por procedimento (7,4% foi semelhante à relatada na literatura mundial. A taxa de mortalidade perinatal (20% foi mais elevada do que a relatada na literatura estrangeira, mas inferior à relatada em estudo conduzido no Brasil, no qual a prevalência de fetos hidrópicos foi semelhante.Objective: to report 54 intrauterine intravascular transfusions (IITs, describing procedure related complications and associated perinatal morbidity and mortality. Methods: fetuses undergoing IITs at Clínica Materno-Fetal and Maternidade Carmela Dutra, Florianópolis, SC, between January 1992 and August 1997 were included in the study. Patients demographics, procedure and newborn related data were tabulated for analysis and presented in descriptive form

  5. Tratamento das pacientes sintomáticas portadoras de miomas uterinos através da associação das técnicas de embolização dos miomas e ligadura endovascular das artérias uterinas

    OpenAIRE

    Ricardo Augusto de Paula Pinto

    2007-01-01

    Os miomas uterinos são os tumores benignos mais comuns do trato genital feminino, sendo que nas mulheres portadoras, 30% são sintomáticos e exigem alguma forma de tratamento. No presente estudo, foram tratadas 35 pacientes sintomáticas com diagnóstico clínico e ultra-sonográfico de mioma uterino, por meio da embolização dos miomas com partículas de polivinil-álcool associadas à obstrução das artérias uterinas com micromolas fibradas. A avaliação clínica e ecográfica foram inicialmente feitas ...

  6. Comparación de cuatro métodos de restauración del adn en muestras de plasma y láminas de citología cérvico-uterina como una herramienta para mejorar la calidad de la muestra

    OpenAIRE

    Marquez, Pilar caterin

    2011-01-01

    Objetivos: comparar cuatro métodos de restauración del adn en plasma y láminas cérvico-uterinas como una herramienta para mejorar la calidad de la muestra. Métodos: a 20 muestras de plasma sanguíneo y 20 muestras de láminas citológicas, se les realizó aislamiento de adn mediante kit comercial y fenol-cloroformo. A todas las muestras se les realizó un tratamiento pre-pcr con cuatro diferentes tipos de actividad de adn polimerasa: 1. Exonucleasa y endonucleasa 5’-3’. 2. Exonucleasa 5’-3’. 3. Kl...

  7. Xeno-free culture condition for human bone marrow and umbilical cord matrix-derived mesenchymal stem/stromal cells using human umbilical cord blood serum

    Science.gov (United States)

    Esmaeli, Azadeh; Moshrefi, Mojgan; Shamsara, Ali; Eftekhar-vaghefi, Seyed Hasan; Nematollahi-mahani, Seyed Noureddin

    2016-01-01

    Background: Fetal bovine serum (FBS) is widely used in cell culture laboratories, risk of zoonotic infections and allergic side effects create obstacles for its use in clinical trials. Therefore, an alternative supplement with proper inherent growth-promoting activities is demanded. Objective: To find FBS substitute, we tested human umbilical cord blood serum (hUCS) for proliferation of human umbilical cord matrix derived mesenchymal stem cells (hUC-MSCs) and human bone marrow-derived mesenchymal cells (hBM-MSCs). Materials and Methods: Umbilical cord blood of healthy neonates, delivered by Caesarian section, was collected and the serum was separated. hUC-MSCs and hBM-MSCs were isolated and characterized by assessment of cell surface antigens by flow cytometry, alkaline phosphatase activity and osteogenic/adipogenic differentiation potential. The cells were then cultured in Iscove's Modified Dulbecco's Medium (IMDM) by conventional methods in three preparations: 1- with hUCS, 2- with FBS, and 3- without serum supplements. Cell proliferation was measured using WST-1 assay, and cell viability was assessed by trypan blue staining. Results: The cells cultured in hUCS and FBS exhibited similar morphology and mesenchymal stem cells properties. WST-1 proliferation assay data showed no significant difference between the proliferation rate of either cells following hUCS and FBS supplementation. Trypan blue exclusion dye test also revealed no significant difference for viability between hUCS and FBS groups. A significant difference was detected between the proliferation rate of stem cells cultured in serum-supplemented medium compared with serum-free medium. Conclusion: Our results indicate that human umbilical cord serum can effectively support proliferation of hBM-MSCS and hUC-MSCs in vitro and can be used as an appropriate substitute for FBS, especially in clinical studies. PMID:27738658

  8. Biopsia de la arteria temporal: revisión de indicaciones y técnica quirúrgica para cirujanos plásticos Temporal artery biopsy: review of indications and surgical technique for plastic surgeons

    Directory of Open Access Journals (Sweden)

    A. Rodríguez Lorenzo

    2007-06-01

    Full Text Available La arteritis de células gigantes (ACG es una vasculitis que presenta complicaciones graves si no es diagnosticada y tratada precozmente con corticoides a altas dosis. La biopsia de la arteria temporal (BAT es la técnica diagnóstica estandarizada utilizada para confirmar la enfermedad. Se trata de una técnica sencilla y con poca morbilidad. No obstante, en la actualidad existe una controversia sobre su indicación en pacientes con sospecha clínica de arteritis sin síntomas craneales debido a la baja tasa de positividad de la biopsia. Presentamos en este trabajo una serie de 28 pacientes en los que se realizaron 30 BAT con el objetivo de revisar las indicaciones y describir la técnica quirúrgica utilizada.Giant cell arteritis is a vasculitis that presents serious complications if it is not diagnosed and treated prematurely with corticosteroids to high dose. The temporal artery biopsy is the gold estandar technique of diagnosis used to confirm the disease. It is a simple technique with little morbidity. Nevertheless, currently there is a controversy on its indication in patients with clinical suspicion of arteritis without craneal symptoms because of the downward rate of positiveness of the biopsy. We present in this work a serie of 28 patients in which 30 biopsies were carried out with the objective to review the indications and to describe the surgical technique utilized.

  9. Studies on Catheterization of Fetal Arteria Mbilicalis Uterus of Pregant Sheep%妊娠山羊宫内胎儿脐动脉插管手术方法的研究

    Institute of Scientific and Technical Information of China (English)

    谭聪; 杨淑华; 何剑斌

    2014-01-01

    为了优化山羊胎儿脐动脉插管模型,本试验采用医用硬膜外导管对单胎妊娠120日龄的山羊进行胎儿脐动脉插管手术,对其手术途径、导管类型、插管方法、麻醉和术后护理进行研究。术后可顺利采集胎儿血液样本,1周后母山羊正常分娩。本试验建立的山羊胎儿脐动脉插管模型的手术方案,可为胎儿疾病的诊断及临床用药等提供试验基础。%In order to optimize the model of catheterization in goat fetal umbilical artery,medi-cal epidural catheter was used on the 120 days age single pregnant goats fetal umbilical artery. The surgical approach, types of catheter, anesthesia and postoperative care were investigated. Blood samples were successfully collected after surgery and one week later stepmother goat could normally be delivered.Surgical options of goats umbilical artery model was established in this test to provides an experimental basis for the diagnosis and clinical treatment of diseases such as fetal.

  10. BANCO DE SANGUE DE CORDÃO UMBILICAL E PLACENTÁRIO: MODELO BRASILEIRO

    Directory of Open Access Journals (Sweden)

    Soraya Andreassa Neves

    2012-01-01

    Full Text Available O cordão umbilical age como um elo de ligação entre a placenta e o embrião durante a gestação e pode ser necessário anos após o nascimento. As células-tronco do sangue de cordão umbilical e placentário possibilitam ser utilizadas como alternativa em transplantes, substituindo os métodos convencionais que empregam células tronco originárias da medula óssea,no tratamento de doenças hematológicas e oncológicas. Este artigo apresenta as regulamentações atuais sobre os bancos de armazenamento do sangue de cordão umbilical e placentário no cenário brasileiro. Para fins comparativos, são apresentados as regulamentações e modelos específicos de dois bancos de armazenamento internacionais. O uso potencial do sangue de cordão umbilical e placentário, como por exemplo, nas pesquisas relacionadas à medicina regenerativa, é descrito e pode levar a um novo questionamento do modelo atual de armazenamento, envolvendo discussões técnicas, legais e éticas.

  11. Umbilical hernia rupture with evisceration of omentum from massive ascites: a case report.

    LENUS (Irish Health Repository)

    Good, Daniel W

    2011-01-01

    The incidence of hernias is increased in patients with alcoholic liver disease with ascites. To the best of our knowledge, this is the first report of an acute rise in intra-abdominal pressure from straining for stool as the cause of a ruptured umbilical hernia.

  12. Does the presence of umbilical outpouchings affect the behaviour of pigs during the day of slaughter?

    DEFF Research Database (Denmark)

    Schild, Sarah-Lina Aagaard; Brandt, Pia; Rousing, Tine;

    2015-01-01

    The aim of the present study was to examine behavioural and clinical consequences of the presence of umbilical outpouchings (UOs) in pigs during the day of slaughter, in order to establish new knowledge of relevance for the assessment of fitness for transport of these animals. Based on the Danish...

  13. Laparoscopic umbilical hernia repair in the presence of extensive paraumbilical collateral veins: A case report

    NARCIS (Netherlands)

    S.S. Lases (Seilenna); H.H. Eker (Hasan); E.G.J.M. Pierik; P. Klitsie (Pieter); B. de Goede (Barry); M.P.F.V. Peeters; G. Kazemier (Geert); J.F. Lange (Johan)

    2011-01-01

    textabstractA patient with an umbilical hernia presenting with collateral veins in the abdominal wall and umbilicus is a case that every hernia surgeon has to deal with occasionally. Several underlying diseases have been described to provoke collateral veins in the abdominal wall. However, the treat

  14. Migration capacity of human umbilical cord mesenchymal stem cells towards glioma in vivo*

    Institute of Scientific and Technical Information of China (English)

    Cungang Fan; Dongliang Wang; Qingjun Zhang; Jingru Zhou

    2013-01-01

    High-grade glioma is the most common malignant primary brain tumor in adults. The poor prognosis of glioma, combined with a resistance to currently available treatments, necessitates the ment of more effective tumor-selective therapies. Stem cel-based therapies are emerging as novel cel-based delivery vehicle for therapeutic agents. In the present study, we successful y isolated human umbilical cord mesenchymal stem cel s by explant culture. The human umbilical cord senchymal stem cel s were adherent to plastic surfaces, expressed specific surface phenotypes of mesenchymal stem cel s as demonstrated by flow cytometry, and possessed multi-differentiation potentials in permissive induction media in vitro. Furthermore, human umbilical cord mesenchymal stem cel s demonstrated excel ent glioma-specific targeting capacity in established rat glioma models after intratumoral injection or contralateral ventricular administration in vivo. The excellent glioma-specific targeting ability and extensive intratumoral distribution of human umbilical cord mesenchymal stem cel s indicate that they may serve as a novel cel ular vehicle for delivering the-rapeutic molecules in glioma therapy.

  15. [Thrombosis of the right atrium after umbilical venous catheterization. Favourable outcome after early thrombectomy].

    Science.gov (United States)

    Paupe, A; Lenclen, R; Blanc, P; Chassevent, J; Hoenn, E; Molho, M; Zannier, D; Olivier-Martin, M

    1992-02-01

    A case of right atrial thrombosis after venous umbilical catheterization in a 21 day-old premature newborn is reported. The initiating factors of such an accident and its clinical signs are evocated. The authors emphasize the value of a systematic ultrasonographic supervision of newborns with central catheters for a long period of time and the value of surgical thrombectomy.

  16. Unstimulated platelets evoke calcium responses in human umbilical vein endothelial cells

    NARCIS (Netherlands)

    van IJzendoorn, S C; van Gool, R G; Reutelingsperger, C P; Heemskerk, Johan W. M.

    1996-01-01

    Interactions between human platelets and human umbilical vein endothelial cells (HUVEC) were studied by monitoring changes in cytosolic [Ca2+]i in both cell types. Confluent monolayers of Fura-2-loaded HUVEC, grown on gelatin-coated coverslips, responded to repeated addition of a suspension of unsti

  17. Early vs delayed clamping of the umbilical cord in full term, preterm and very preterm infants

    DEFF Research Database (Denmark)

    Moller, N.K.; Weber, T.

    2008-01-01

    Randomized studies from 2006 and two meta-analyses published in 2007 agree that clamping of the umbilical cord can be delayed. For the preterm and very preterm infant benefits include less need for blood transfusion and less morbidity, especially for the very preterm male infant. For the term...

  18. A case report of congenital umbilical arteriovenous malformation complicated with liver failure after surgical excision

    Science.gov (United States)

    Han, Ji-Won; Kim, Hyun-Young; Jung, Sung-Eun

    2017-01-01

    Abstract Rationale: Few case reports of umbilical arteriovenous malformation (AVM) have been reported. Herein, we report a neonatal case of umbilical AVM who underwent liver failure after surgical excision. Patient concerns: The patient was a girl delivered at a gestational age of 39+5 weeks showing cyanosis and heart murmur. Diagnoses: Cardiac echography, abdominal ultrasonography (USG), and computed tomography revealed suspecting the umbilical AVM. Interventions: On the eighth day after birth, because of the aggravation of heart failure, emergency surgery for excision of umbilical AVM was performed. Outcomes: In postoperative state, worsened laboratory test of liver function and coagulopathy indicated the liver failure. Abdominal USG revealed that the portal vein (PV) flow primarily occurred from the left PV to the inferior vena cava via ductus venosus and coarse hepatic echogenicity. After conservative management, laboratory findings of liver function and the flow direction of the left PV were normal, as demonstrated by abdominal USG within 50th postoperative day. Lessons: Careful preoperative evaluation of an AVM of a large size with significant blood flow should be performed, and the possibility of liver failure after surgery should always be considered. PMID:28178121

  19. Fatores Prognósticos para o Óbito Perinatal em Gestações com Diástole Zero ou Reversa na Dopplervelocimetria das Artérias Umbilicais Prognostic Parameters for Perinatal Death in Pregnancies with Absent or Reversed End-Diastolic Flow Velocity in the Umbilical Arteries

    Directory of Open Access Journals (Sweden)

    Roseli Mieko Yamamoto

    2000-01-01

    Full Text Available Objetivos: estudar os fatores prognósticos para o óbito perinatal em gestações com diagnóstico de diástole zero (DZ ou reversa (DR na dopplervelocimetria das artérias umbilicais. Métodos: foram analisadas retrospectivamente 204 gestantes com DZ ou DR, sendo realizados os exames de cardiotocografia, perfil biofísico fetal, índice do líquido amniótico e dopplervelocimetria do ducto venoso e das artérias umbilicais, uterinas, aorta e cerebral média. Em 170 casos foi aplicado o modelo de regressão logística para determinar a variável com melhor acurácia na predição do óbito perinatal. Resultados: a mortalidade foi de 28 casos de óbito fetal (13,7% e 45 de óbito pós-natal (22,1%. Houve correlação significativa entre os óbitos e as variáveis analisadas. A proporção de óbitos no grupo com recém-nascidos de peso inferior a 1.000 g foi de 74,7% e no grupo com idade gestacional inferior a 31 semanas, de 66,3%. Na regressão logística, o peso do recém-nascido foi a melhor variável capaz de predizer o óbito perinatal (pPurpose: to study the prognostic parameters for perinatal death in pregnancies with absent or reversed end-diastolic flow velocity on umbilical artery dopplervelocimetry. Methods: two hundred and four pregnancies were retrospectively reviewed. The methods used were cardiotocography, fetal biophysical profile, amniotic fluid index and dopplervelocimetry of ductus venosus, fetal aorta, middle cerebral artery, umbilical arteries and uterine artery. The logistic regression model was applied to one hundred and seventy cases in order to determine the most accurate variable for predicting perinatal death. Results: the mortality rates were: 28 cases of intrauterine fetal death (13.7% and 45 neonatal deaths (22.1%. A statistically significant correlation was found between death and the studied variables. The perinatal death rate in the group with birth weight below 1,000 g was 74.7%, and in the group with

  20. Comparison of Maternal and Umbilical Cord Blood Selenium Levels in Low and Normal Birth Weight Neonates

    Directory of Open Access Journals (Sweden)

    Lyly Nazemi

    2015-10-01

    Full Text Available Objective:To compare the maternal and umbilical cord serum selenium concentrations in Low and normal birth weight neonates.Materials and methods:A case-control study was carried out in Vali-Asr and Akbarabadi Hospitals (Jan. to Dec. 2013. Two groups; case group; 91 mothers who delivered a low birth weight (LBW neonate and control group; 86 subjects who delivered a normal birth weight neonate were selected. Immediately after birth, 5 ml of maternal blood and umbilical cord blood were collected, and sent to laboratory to assay Se concentrations. To compare both groups' blood Se concentration, data were analyzed in SPSS 16.0.Results:Eighty six (48.6% mothers with normal birth weight neonates and 91 (51.4% mothers with low birth weight infants entered the study. Mean maternal mothers' age and mean maternal blood Se were 28.55+5.90 years and 79.3756+26.46915. A significant association was seen between maternal blood and cord blood Se level in control and case group (P value<0.0001, r = 0.69 and(P value<0.001, r = 0.79. On the other hand no differences were seen between 2 groups' maternal blood Se level (P Value = 0.65. Umbilical Cord blood Se concentration was not also different between case and control group (P value = 0.46.Conclusion:We found that maternal and umbilical cord blood Se concentrations were not different in low and adequate birth weight infants, however; umbilical cord Se concentrations were positively correlated with maternal blood Se concentrations.

  1. A Collective Review on Mesh-Based Repair of Umbilical and Epigastric Hernias.

    Science.gov (United States)

    Ponten, Jeroen E H; Thomassen, Irene; Nienhuijs, Simon W

    2014-10-01

    In accordance with the tension-free principles for other hernias, umbilical and epigastric hernia repair should probably be mesh-based. The number of randomized studies is increasing, most of them showing significantly less recurrences with the use of a mesh. Different devices are available and are applicable by several approaches. The objective of this review was to evaluate recent literature for the different types of mesh for umbilical and epigastric hernia repair and recurrences after mesh repair. A multi-database search was conducted to reveal relevant studies since 2001 reporting mesh-based repair of primary umbilical/epigastric hernia and their outcomes in adult patients. A total of 20 studies were included, 15 of them solely involved umbilical hernias, whereas the remaining studies included epigastric hernias as well. A median of 124 patients (range, 17-384) was investigated per study. Three quarters of the included studies had a follow-up of at least 2 years. Six studies described the results of laparoscopic approach, of which one reported a recurrence rate of 2.7 %; in the remaining studies, no recurrences occurred. Two comparative studies reported a lower incidence of complications and postoperative pain after laparoscopic repair compared to open repair. Seventeen studies reported results of open techniques, of which seven studies showed no recurrence. Other studies reported recurrence rates up to 3.1 %. A wide range of complication rates were reported (0-33 %). This collective review showed acceptable recurrence rates for mesh-based umbilical and epigastric hernia repair. A wide range of devices was investigated. A tendency toward more complications after laparoscopic repair was found compared to open repair.

  2. Laparoscopic cholecystectomy accompanied by simultaneous umbilical hernia repair: A retrospective study

    Directory of Open Access Journals (Sweden)

    Kamer E

    2007-01-01

    Full Text Available Background : Umbilical defects may cause technical problems for general surgeons in patients during laparoscopic cholecystectomy (LC operations and may increase the incidence of incisional hernia. Aim : The objectives of this study were to determine the optimal repair method for umbilical hernias that already exist or are encountered incidentally and to present data regarding potential problems that may occur during LC. Settings and Design : Medical records of patients who had received simultaneous umbilical hernia repair (UHR with LC were investigated retrospectively. Materials and Methods : Cholelithiasis was accompanied by umbilical hernia in 64 (8.6% out of 745 patients who underwent LC and UHR simultaneously in our hospital between 2000 and 2004. Statistical Analysis Used : The Mann-Whitney U, Chi-square, One-Way Anova, Kaplan-Meier survival analysis, the log-rank test and t test were used for statistical analyses. Results : LC was followed by UHR using primary suture (Group 1, Mayo repair (Group 2 and flat mesh-based repair (Group 3 in 32 (50%, 18 (28.1% and 14 (21.9% patients, respectively. Mean body mass indexes (BMI of patients were 26.6 kg/m 2 , 29.2 kg/m 2 and 39.9 kg/m 2 in Groups 1, 2 and 3, respectively. Recurrence rates were 9.4%, 5.6% and none (0% in Groups 1, 2 and 3, respectively. Recurrence was observed in three (7.0% out of 43(67.2% patients with BMI≥30 kg/m 2 while umbilical hernia recurred in one (4.8% out of 21 (32.8% patients with BMI< 30 kg/m 2 . Overall morbidity and mortality rates were 14.1% and 0%, respectively. Conclusions : The outcomes of the UHR with mesh after laparoscopic surgeries appear to be better for either obese or non-obese patients than primary suture techniques in recurrence rates.

  3. Simultaneous measurements of umbilical uptake, fetal utilization rate, and fetal turnover rate of glucose.

    Science.gov (United States)

    Hay, W W; Sparks, J W; Quissell, B J; Battaglia, F C; Meschia, G

    1981-06-01

    Fetal umbilical glucose uptake was compared with simultaneous measurements of glucose turnover and utilization rates in 12 pregnant sheep, at a mean of 137 days gestational age (range, 118-146 days). Umbilical glucose uptake was calculated by application of the Fick principle. Fetal glucose turnover rate was measured by a primed-constant infusion of [14C]- and [3H]glucose (glucose turnover rate = tracer infusion rate divided by fetal glucose sp act). The calculation of fetal glucose utilization rate required substraction of the loss of tracer to the placenta from the tracer infusion rate, thus defining the net tracer entry into the fetus for direct comparison with the net umbilical glucose uptake. In fed, normoglycemic sheep, these measurements demonstrated statistical equivalence of umbilical glucose uptake rate (4.77 mg.min-1.kg-1 +/- 0.34 SE) and glucose utilization rate ([14C]glucose, 5.58 mg.min-1.kg-1 +/- 0.54 SE; and [3H]glucose, 7.19 mg.min-1.kg-1 +/- 1.24 SE) when tested by two-way analysis of variance (P greater than 0.1). In three fasted, hypoglycemic sheep, the umbilical glucose uptake rate fell to 1.43 mg.min-1.kg-1 +/- 0.56 SE, which was considerably lower than the simultaneous glucose utilization rate ([14C]glucose, 4.78 mg.min-1.kg-1 +/- 0.48 SE; and [3H]glucose, 6.81 mg.min-1.kg-1 +/- 2.19 SE). Thus, in the normoglycemic, late-gestation fetal lamb, there appears to be little glucogenesis, whereas glucogenesis may become significant during fasting-induced fetal hypoglycemia.

  4. Modelo tridimensional em elementos finitos para a análise de cabo umbilical STU submetido ao carregamento de crushing.

    OpenAIRE

    William Corrêa Guttner

    2016-01-01

    Este trabalho desenvolve e apresenta um modelo tridimensional em elementos finitos de um cabo umbilical do tipo STU (Steel Tube Umbilical) utilizado na extração offshore de petróleo. Tal modelo é utilizado para estudar o carregamento de crushing, que é imposto ao cabo umbilical pelas sapatas do tensionador durante o seu lançamento, de modo a obter de forma detalhada a distribuição de tensões nos componentes do núcleo, com foco nos tubos de aço utilizados para o transporte de fluidos. A metodo...

  5. [Hernia surgery in urology: part 1: inguinal, femoral and umbilical hernias - fundamentals of clinical diagnostics and treatment].

    Science.gov (United States)

    Franz, T; Schwalenberg, T; Dietrich, A; Müller, J; Stolzenburg, J-U

    2013-05-01

    Hernias are a common occurrence with correspondingly huge clinical and economic impacts on the healthcare system. The most common forms of hernia which need to be diagnosed and treated in routine urological work are inguinal and umbilical hernias. With the objective of reconstructing and stabilizing the inguinal canal there are the possibilities of open and minimally invasive surgery and both methods can be performed with suture or mesh repair. Indications for surgery of umbilical hernias are infrequent although this is possible with little effort under local anesthesia. This article presents an overview of the epidemiology, pathogenesis, clinical symptoms, diagnostics and therapy of inguinal, femoral and umbilical hernias.

  6. Tolerância da placenta à parada circulatória umbilical normotérmica Tolerance of placenta to normothermic umbilical circulatory arrest

    Directory of Open Access Journals (Sweden)

    Renato S Assad

    1992-09-01

    Full Text Available O aumento da resistência vascular placentáriae distúrbios de trocas gasosas freqüentemente ocorrem após a circulação extracorpórea (CEC fetal. A utilização de um circuito convencional de CEC que exclua a placenta da circulação através do clampeamento temporário do cordão umbilical pode proteger a vasculatura placentária dos estímulos que levam ao aumento da resistência vascular. Para avaliar a tolerância placentária à parada normotérmica do fluxo sangüíneo umbílico-placentário, 9 placentas de ovelhas isoladas in-situ, foram colocadas em CEC através da canulação dos vasos umbilicais, com fluxo médio de artéria umbilical de 214 ml/min/kg. Após 30 minutos de estabelecimento da CEC, a circulação placentária foi interrompida por 30 minutos, simulando o clapeamento do cordão umbilical durante a CEC fetal total. Posteriormente, a circulação placentária foi restabelecida aos valores basais. A troca de gases placentária, o fluxo sangüíneo e a resistência vascular materno-placentários foram avaliados antes e depois da parada circulatória. Não houve diferença estatisticamente significante entre os gradientes transplacentários de pO2 e pCO2, indicando que a interrupção do fluxo sangüíneo placentário por 30 minutos, em condições normotérmicas, não afeta a função placentária. Este modelo sugere um método alternativo para a aplicação clínica da CEC fetal, através da exclusão da circulação umbílico-placentária durante a CEC fetal, eliminandose, assim, os efeitos deletérios da CEC nas trocas gasosas placentárias.Elevation of placental vascular resistance (PVR and depression of fetal gas exchange occurs after fetal cardiopulmonary bypass (CPB. Excluding the placenta from the CPB circuit may protect the placental vasculature from the unwanted stimuli which lead to elevated PVR. To evaluate this approach, 9 isolated in-situ sheep placentas were placed on CPB by cannulating the umbilical vessels

  7. A comparative study on the uniaxial mechanical properties of the umbilical vein and umbilical artery using different stress-strain definitions.

    Science.gov (United States)

    Karimi, Alireza; Navidbakhsh, Mahdi

    2014-12-01

    The umbilical cord is part of the fetus and generally includes one umbilical vein (UV) and two umbilical arteries (UAs). As the saphenous vein and UV are the most commonly used veins for the coronary artery disease treatment as a coronary artery bypass graft (CABG), understating the mechanical properties of UV has a key asset in its performance for CABG. However, there is not only a lack of knowledge on the mechanical properties of UV and UA but there is no agreement as to which stress-strain definition should be implemented to measure their mechanical properties. In this study, the UV and UA samples were removed after caesarean from eight individuals and subjected to a series of tensile testing. Three stress definitions (second Piola-Kichhoff stress, engineering stress, and true stress) and four strain definitions (Almansi-Hamel strain, Green-St. Venant strain, engineering strain, and true strain) were employed to determine the linear mechanical properties of UVs and UAs. The nonlinear mechanical behavior of UV/UA was computationally investigated using hyperelastic material models, such as Ogden and Mooney-Rivlin. The results showed that the effect of varying the stress definition on the maximum stress measurements of the UV/UA is significant but not when calculating the elastic modulus. In the true stress-strain diagram, the maximum strain of UV was 92 % higher, while the elastic modulus and maximum stress were 162 and 42 % lower than that of UA. The Mooney-Rivlin material model was designated to represent the nonlinear mechanical behavior of the UV and UA under uniaxial loading.

  8. Integration of umbilical venous and arterial Doppler flow parameters for prediction of adverse perinatal outcome

    Directory of Open Access Journals (Sweden)

    Hebbar Shripad

    2015-01-01

    Full Text Available Background: Quantification of umbilical vein (UV blood flow rate and umbilical artery Doppler indices might be valuable in assessing fetuses at increased risk of perinatal complications as they receive their supply of oxygen and nutrients through this vessel. Previous studies have indicated that UV blood volume flow rate to umbilical artery pulsatility index (UAPI ratio (venous arterial index [VAI] evaluates both venous and arterial arm of fetal umbilical circulation and hence, can be adopted as a screening tool in management of high risk pregnancy. Objectives: To compare umbilical VAI with adverse perinatal outcome and also to evaluate its efficacy with other flow indices in determining perinatal outcome. Materials and Methods: Various Doppler indices such as normalized blood flow rate in UV (nUV, ml/kg estimated fetal weight/min, VAI (nUV/UAPI, umbilical artery resistance index (RI, UAPI, and systolic diastolic ratio were determined in 103 pregnant women within 2 weeks of the delivery. A risk score was devised using APGAR at 5 min, birth weight, preterm delivery, fetal distress, Neonatal Intensive Care Unit (NICU care, and perinatal death and this score was correlated with antenatal Doppler findings. Results: Subjects with low VAI were found to have a greater association with intrauterine growth restricted fetuses (28.5% and low liquor (35.7%, preterm deliveries (46.4%, lower mean birth weight (2.25 kg, higher NICU admission rates (32.1%. The unfavorable score was noticed in 25.2% of the neonates. They had lower VAI (156 vs. 241, UV diameter (6.2 mm vs. 7.8 mm, UV velocity (16.2 vs. 17.8, nUV (163.7 vs. 206.4, and higher PI (1.3 vs. 0.9. A cut-off of VAI of 105 ml/kg/min had sensitivity of 86.7% and a specificity of 93.5% for predicting poor perinatal outcome. Conclusion: VAI with a cut-off of 105 ml/kg/min can be used as an additional tool along with the other conventional Doppler indices in order to predict adverse fetal outcome.

  9. An experimental study of preventing and treating acute radioactive enteritis with human umbilical cord mesenchymal stem cells

    Institute of Scientific and Technical Information of China (English)

    Rui Wang; Wei Yuan; Qiang Zhao; Peng Song; Ji Yue; Shi-De Lin; Ting-Bao Zhao

    2013-01-01

    Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus to provide clinical therapeutic basis for radiation sickness.Methods:Human umbilical cord-derived mesenchymal stem cells were cultivatedin vitro and the model of acute radioactive enteritis of rats was established.Then, the umbilical cord mesenchymal stem cells were injected into the rats via tail vein.Visual and histopathological changes of the experimental rats were observed.Results:After the injection, the rats in the prevention group and treatment group had remarkably better survival status than those in the control group.The histological observations revealed that the former also had better intestinal mucosa structure, more regenerative cells and stronger proliferation activity than the latter.Conclusions:Human umbilical cord-derived mesenchymal stem cells have a definite therapeutic effect on acute radioactive enteritis in rats.

  10. Illthrift in Suckling Lambs Secondary to Umbilical Infections and Possible Implication of Cryptosporidiosis as a Risk Factor

    Directory of Open Access Journals (Sweden)

    Nektarios D. Giadinis

    2011-01-01

    Full Text Available Illthrift was observed in 20/60 lambs aged 40–45 days in a dairy sheep flock in Greece. Cryptosporidiosis had been diagnosed and successfully treated with halofuginone lactate a month earlier. Parasitological examinations were negative for endoparasites while hematology and biochemistry were unremarkable. Necropsy of 5 lambs revealed lung and liver abscessation, presumably secondary to umbilical infections due to poor farm hygiene, though umbilical lesions were not observed. No new cases were observed following treatment of the umbilicus of newborn lambs with chlorexidine. Although umbilical infections are common, this is the first reported case of illthrift in lambs attributed to umbilical infection; illthrift may be the only clinical manifestation of such infections. The prior presence of cryptosporidiosis may have contributed to the severity of the infection through the reduction of local immunity. Recognition of this possibly underdiagnosed or underappreciated condition may improve medical, production, and welfare standards in the sheep industry.

  11. Case Report: Pre- and postnatal management of an allantoic cyst with patent urachus and single umbilical artery

    OpenAIRE

    Trong Thach, Than; Duy Quan, Vo; Diem Nghi, Tran; Hoang Anh, Nguyen; Phi Hung, Le; Thien Luan, Nguyen; Phuoc Long, Nguyen; Serour, Gamal; Svigos, John

    2015-01-01

    Patent urachus is a rare congenital abnormality. Since its first description by Cabriolus in 1550, few cases have been reported. A 26-year-old Vietnamese primigravida presented at 20 weeks of gestation for evaluation of a cystic mass in the umbilical cord, which was first discovered at week 13 of pregnancy by ultrasound scan. The cystic mass originated from the root of the umbilical cord, connected to the urinary bladder, and no intestinal contents were enclosed within. Doppler ultrasound ass...

  12. Comparison of herniorrhaphy versus clamping of umbilical hernias in horses: a retrospective study of 93 cases (1982-1994).

    OpenAIRE

    1996-01-01

    Many uncomplicated umbilical hernias have been managed successfully in foals by the application of a hernia clamp. Isolated reports of complications following clamp application have led some authors to suggest that it is an unsuitable method of treatment. Little information has been published comparing the complication rates associated with the use of hernia clamps and herniorrhaphy in the treatment of umbilical hernias. The purpose of this retrospective study was to report the characteristic...

  13. Monitorización ultrasonográfica de endarterectomía carotídea y angioplastia transluminal percutánea como procedimientos de revascularización carotídea en estenosis de alto grado de la arteria carótida interna extracraneal

    OpenAIRE

    Benavente Fernández, Lorena

    2014-01-01

    INTRODUCCIÓN El ictus aterotrombótico por ateromatosis carotídea, es el responsable del 15-20% de todos los ictus. Siendo la arteria carótida interna (ACI) un vaso principal para la irrigación del parénquima cerebral, cuando dicha ateromatosis condiciona una estenosis significativa con alto riesgo tromboembólico se plantea la necesidad de un tratamiento revascularizador. La endarterectomía carotídea (EAC) y la angioplastia endoluminal (ASC) con o sin implante de stent son las dos opciones ...

  14. 介入化疗栓塞术联合体外高频热疗治疗晚期肝癌临床观察%The clinical observation of transcatheter arteria chemoembolization combined with external high frequency thermotherapy for advanced hepatic cancer

    Institute of Scientific and Technical Information of China (English)

    郑剑霄; 吴万垠; 邓宏; 龙顺钦

    2009-01-01

    Objective To evaluate the efficacy and side effects of transeatheter arteria chemoembolization combined with external high frequency thermotherapy for advanced hepatic cancer.Methods Thirty nine patients were randomly divided into 2 groups ,one group with 19 cases,the other 20 cases.The observed group was treated by transcatheter arteria.chemoembolization combined with external high frequency thermotherapy,and the control group by ordinary transcatheter arteria chemoembolization.Result The response rate with the observed group and control group were 73.7%(14/19) and 40%(8/20)respeetively(P<0.05),and its side effects was not increased.There was no significant difference in the survival rate.Conclusions The short term efficacy of the advanced hepatic cancer is improved by transcatheter arteria chemoembolization combined with external high frequency thermotherapy and its side effects is not increased.%目的 比较介入化疗栓塞术联合体外高频热疗与单纯介入化疗栓塞术治疗晚期肝癌的疗效和毒副反应.方法 39例晚期原发性肝癌患者随机分为两组,观察组19例,对照组20例.观察组行介入化疗栓塞术联合体外高频热疗,对照组行单纯介入化疗栓塞术治疗.结果 观察组总有效率73.7%(14/19);对照组总有效率40%(8/20),观察组的治疗有效率较对照组明显提高(P<0.05),毒副反应未增加.0.5年、1年生存率两组差异无显著性(P>0.05).结论 介入化疗栓塞术联合体外高频热疗提高了晚期肝癌的近期疗效,且不增加毒副作用.

  15. Audio spectrum analysis of umbilical artery Doppler ultrasound signals applied to a clinical material.

    Science.gov (United States)

    Thuring, Ann; Brännström, K Jonas; Jansson, Tomas; Maršál, Karel

    2014-12-01

    Analysis of umbilical artery flow velocity waveforms characterized by pulsatility index (PI) is used to evaluate fetoplacental circulation in high-risk pregnancies. However, an experienced sonographer may be able to further differentiate between various timbres of Doppler audio signals. Recently, we have developed a method for objective audio signal characterization; the method has been tested in an animal model. In the present pilot study, the method was for the first time applied to human pregnancies. Doppler umbilical artery velocimetry was performed in 13 preterm fetuses before and after two doses of 12 mg betamethasone. The auditory measure defined by the frequency band where the spectral energy had dropped 15 dB from its maximum level (MAXpeak-15 dB ), increased two days after betamethasone administration (p = 0.001) parallel with a less pronounced decrease in PI (p = 0.04). The new auditory parameter MAXpeak-15 dB reflected the changes more sensitively than the PI did.

  16. Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury

    Institute of Scientific and Technical Information of China (English)

    CAO Fu-jiang; FENG Shi-qing

    2009-01-01

    Objective To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) and advances in the treatment of spinal cord injury, Data sources Published articles (1983-2007) about hUCMSCs and spinal cord injury were selected using Medline. Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation in spinal cord injury therapy. Of 258 originally identifiied arises 51 were selected that specifically addressed the stated purpose. Results Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bone marrow and are more appropriate to transplantation for cell based therapies. Conclusions Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play an important role in the treatment of spinal cord injury.

  17. Omentum in the pediatric umbilical hernia: is it a potential alarm for the appearance of complications?

    Science.gov (United States)

    Sinopidis, Xenophon; Panagidis, Antonios; Alexopoulos, Vasileios; Karatza, Ageliki; Mitropoulou, Konstantina; Varvarigou, Anastasia; Georgiou, George

    2012-01-01

    Umbilical hernia is a common benign condition which resolves spontaneously during the first five years of life. However, in certain cases there are some characteristics which may be indicative of a different prognostic approach, as they increase the possibility of complications. The two cases of umbilical hernia that we describe here were treated operatively and revealed the presence of strangulated and adhered omentum, respectively. Reflecting on the adhesive properties of the omentum, we hypothesized that this may occur more often than it is believed, especially in those cases that are described as recurrent symptomatic herniations. In such cases, there should be increased alert for the possibility of complications during the period of the conservative expectance for resolution.

  18. Neonatal apgar scores and umbilical blood gas changes in vaginal delivery and cesarean: a comparative study

    Directory of Open Access Journals (Sweden)

    SH. Raafati

    2006-07-01

    Full Text Available Background: Umbilical cord blood gas analysis is a useful method for assessment of oxygenation and acid-base status in neonates. Severe fetal acidemia is associated with increased perinatal mortality and increased risk of subsequent impaired neurological development. Due to high percentage of C/S in our country and the effect of anesthetic medications on umbilical blood gases which can cause neonatal acidosis and hypoxemia, the study of umbilical cord blood gas in vaginal delivery versus cesarean section is mandatory. Methods: In this cross-sectional study one hundred samples were taken from Mostafa Khomeini hospital in summer 2004. The samples were taken immediately of umbilical vein after clamping the umbilical cord and analyzed after 10 minutes. Cases were classified in to 3 groups: vaginal delivery (n=40, elective C/S under general anesthesia (n=35 and C/S under spinal anesthesia (n=25. Duration of anesthesia and its effect on blood gas and infants apgar were assessed. Results: In the first group (vaginal delivery mean blood gase parameters were; pH=7.3064.73, pO2=25.246.87, HCO3=20.562.03, Apgar=8.820.38 and pCO2=41.826.57. In the second group (general anesthesia mean blood gaze parameters were: pH=7.3044.73, pO2=38.7014.02, pCO2=43.265.87, HCO3=21.1113 and apgar score=8.170.7. In the third group (spinal anesthesia mean blood gaze parameters were: pH=7.3014.50, pCO2=44.14.99, HCO3=21.382.15, pO2=26.625.5 and apgar=8.600.62. The apgar scores and pO2 demonstrated significant relationship with type of anesthesia. The apgar score was lower and pO2 was higher in C/S under general anesthesia compared with the other two groups. There was significant relationship between duration of anesthesia and umbilical pO With increasing duration of anesthesia, pO2 was reduced. Between the type of delivery and anesthesia duration with PH, pO2, pCO2 and HCO3 were not meaningful relationship (P<0.05. Conclusion: There

  19. Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy.

    Science.gov (United States)

    Ding, Dah-Ching; Chang, Yu-Hsun; Shyu, Woei-Cherng; Lin, Shinn-Zong

    2015-01-01

    The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs). Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster self-renewal properties. Different derivation protocols may provide different amounts and populations of stem cells. Stem cell populations have also been reported in other compartments of the umbilical cord, such as the cord lining, perivascular tissue, and Wharton's jelly. HUCMSCs are noncontroversial sources compared to embryonic stem cells. They can differentiate into the three germ layers that promote tissue repair and modulate immune responses and anticancer properties. Thus, they are attractive autologous or allogenic agents for the treatment of malignant and nonmalignant solid and soft cancers. HUCMCs also can be the feeder layer for embryonic stem cells or other pluripotent stem cells. Regarding their therapeutic value, storage banking system and protocols should be established immediately. This review critically evaluates their therapeutic value, challenges, and future directions for their clinical applications.

  20. The treatment of neurodegenerative disorders using umbilical cord blood and menstrual blood-derived stem cells.

    Science.gov (United States)

    Sanberg, Paul R; Eve, David J; Willing, Alison E; Garbuzova-Davis, Svitlana; Tan, Jun; Sanberg, Cyndy D; Allickson, Julie G; Cruz, L Eduardo; Borlongan, Cesar V

    2011-01-01

    Stem cell transplantation is a potentially important means of treatment for a number of disorders. Two different stem cell populations of interest are mononuclear umbilical cord blood cells and menstrual blood-derived stem cells. These cells are relatively easy to obtain, appear to be pluripotent, and are immunologically immature. These cells, particularly umbilical cord blood cells, have been studied as either single or multiple injections in a number of animal models of neurodegenerative disorders with some degree of success, including stroke, Alzheimer's disease, amyotrophic lateral sclerosis, and Sanfilippo syndrome type B. Evidence of anti-inflammatory effects and secretion of specific cytokines and growth factors that promote cell survival, rather than cell replacement, have been detected in both transplanted cells.

  1.  Spontaneous Rupture of Umbilical Hernia in Pregnancy: A Case Report

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    Yahaya Ukwenya

    2011-07-01

    Full Text Available  A 28 year old woman presented with a spontaneous rupture of an umbilical hernia in her seventh month of pregnancy. She had four previous unsupervised normal deliveries. There was no history of trauma or application of herbal medicine on the hernia. The hernia sac ruptured at the inferior surface where it was attached to the ulcerated and damaged overlying skin. There was a gangrenous eviscerated small bowel. The patient was resuscitated and the gangrenous small bowel was resected and end to end anastomosis done. The hernia sac was excised and the 12 cm defect repaired. Six weeks later, she had spontaneous vaginal delivery of a live baby. We advocate that large umbilical hernias should be routinely repaired when seen in women of child bearing age.

  2. Omentum in the Pediatric Umbilical Hernia: Is It a Potential Alarm for the Appearance of Complications?

    Directory of Open Access Journals (Sweden)

    Xenophon Sinopidis

    2012-01-01

    Full Text Available Umbilical hernia is a common benign condition which resolves spontaneously during the first five years of life. However, in certain cases there are some characteristics which may be indicative of a different prognostic approach, as they increase the possibility of complications. The two cases of umbilical hernia that we describe here were treated operatively and revealed the presence of strangulated and adhered omentum, respectively. Reflecting on the adhesive properties of the omentum, we hypothesized that this may occur more often than it is believed, especially in those cases that are described as recurrent symptomatic herniations. In such cases, there should be increased alert for the possibility of complications during the period of the conservative expectance for resolution.

  3. Gastro-umbilical fistula as a rare complication of benign gastric ulcer perforation: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ju Young; Jang, Kyung Mi; Yoon, Hoi Soo; Kim, Min Jeong; Lee, Kwan Seop; Lee, Yul; Bae, Sang Hoon [College of Medicine, Hallym University, Anyang (Korea, Republic of)

    2007-11-15

    As fistula occurring between the stomach and other abdominal internal organs or to the surface of the body is usually encountered as a complication of stomach cancer or colon cancer, peptic ulcer disease, or other variable causes. The most common type of gastric fistula is a gastro-colic fistula that is mainly found as a complication of a gastric carcinoma or of a carcinoma of the transverse colon invading each other. Sometimes, a benign gastric ulcer perforation also can cause a gastro-colic fistula. However, as far as we know, a fistula occurring between the stomach and the umbilicus has not been reported. Here we present a case report of a gastro-umbilical fistula in a young woman that manifested as a umbilical discharge.

  4. Enhancing endogenous stem cells in the newbornvia delayed umbilical cord clamping

    Institute of Scientific and Technical Information of China (English)

    Christopher Lawton; Sandra Acosta; Nate Watson; Chiara Gonzales-Portillo; hTeo Diamandis; Naoki Tajiri; Yuji Kaneko; Paul R. Sanberg; Cesar V. Borlongan

    2015-01-01

    There is currently no consensus among clinicians and scientists over the appropriate or optimal timing for umbilical cord clamping. However, many clinical studies have suggested that delayed cord clamping is associated with various neonatal beneifts including increased blood volume, reduced need for blood transfusion, increased cerebral oxygenation in pre-term infants, and decreased frequency of iron deifciency anemia in term infants. Human umbilical cord blood con-tains signiifcant amounts of stem and progenitor cells and is currently used in the treatment of several life-threatening diseases. We propose that delayed cord clamping be encouraged as it en-hances blood lfow from the placenta to the neonate, which is accompanied by an increase supply of valuable stem and progenitor cells, as well as may improve blood oxygenation and increase blood volume, altogether reducing the infant’s susceptibility to both neonatal and age-related diseases.

  5. Human umbilical cord blood mononuclear cell transplantation for delayed encephalopathy after carbon monoxide intoxication

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    Gong D

    2013-08-01

    Full Text Available Dianrong Gong,1 Haiyan Yu,1 Weihua Wang,2 Haixin Yang,1 Fabin Han1,21Department of Neurology, 2Centre for Stem Cells and Regenerative Medicine, Liaocheng People's Hospital, The Affiliated Liaocheng Hospital, Taishan Medical University, Shandong, People's Republic of ChinaAbstract: Stem cell transplantation is one of the potential treatments for neurological disorders. Since human umbilical cord stem cells have been shown to provide neuroprotection and promote neural regeneration, we have attempted to transplant the human umbilical cord blood mononuclear cells (hUCB-MNCs to treat patients with delayed encephalopathy after carbon monoxide intoxication (DEACOI. The hUCB-MNCs were isolated from fresh umbilical cord blood and were given to patients subarachnoidally. Physical examinations, mini-mental state examination scores, and computed tomography scans were used to evaluate the improvement of symptoms, signs, and pathological changes of the patient's brain before and after hUCB-MNC transplantation. A total of 12 patients with DEACOI were treated with hUCB-MNCs in this study. We found that most of the patients have shown significant improvements in movement, behavior, and cognitive function, and improved brain images in 1–4 months from the first transplantation of hUCB-MNCs. None of these patients have been observed to have any severe adverse effects. Our study suggests that the hUCB-MNC transplantation may be a safe and effective treatment for DEACOI. Further studies and clinical trials with more cases, using more systematic scoring methods, are needed to evaluate brain structural and functional improvements in patients with DEACOI after hUCB-MNC therapy.Keywords: human umbilical cord blood mononuclear cells, transplantation, delayed encephalopathy after carbon monoxide intoxication, MMSE

  6. A 26-Year-Old Retained Demised Abdominal Pregnancy Presenting with Umbilical Fistula

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    Nnadi Daniel

    2014-01-01

    Full Text Available This is a report on a 72-year-old postmenopausal woman who presented with passage of fetal bones through an umbilical fistula. She was diagnosed as a case of demised abdominal pregnancy, which had been retained for 26 years. She subsequently had exploratory laparotomy, evacuation of the abdominal pregnancy, hysterectomy, and bowel resection. The patient’s condition remained unstable throughout the postoperative period and she died from septicemia on the eleventh day.

  7. Adipokines in umbilical cord blood from children born large for gestational age

    DEFF Research Database (Denmark)

    Lausten-Thomsen, Ulrik; Christiansen, Michael; Hedley, Paula Louise;

    2016-01-01

    of adipokines and their mutual relationship at birth in children born to non-diabetic mothers. METHODS: Adiponectin, leptin and sOB-R were measured using ELISA-based commercial kits in umbilical cord blood from 60 neonates (30 born large for gestational age [LGA] and 30 born appropriate for gestational age [AGA......]). Children exposed to maternal diabetes, chronic disease and preeclampsia were excluded. RESULTS: The LGA group exhibited significantly elevated concentrations of leptin (p

  8. Human Umbilical Cord Mesenchymal Stem Cells: A New Therapeutic Option for Tooth Regeneration

    OpenAIRE

    Yuanwei Chen; Yongchun Yu; Lin Chen; Lanfeng Ye; Junhui Cui; Quan Sun; Kaide Li; Zhiyong Li; Lei Liu

    2015-01-01

    Tooth regeneration is considered to be an optimistic approach to replace current treatments for tooth loss. It is important to determine the most suitable seed cells for tooth regeneration. Recently, human umbilical cord mesenchymal stem cells (hUCMSCs) have been regarded as a promising candidate for tissue regeneration. However, it has not been reported whether hUCMSCs can be employed in tooth regeneration. Here, we report that hUCMSCs can be induced into odontoblast-like cells in vitro and ...

  9. Molecular characterization of microbial contaminants isolated from Umbilical Cord Blood Units for transplant

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    Juan Manuel Bello-López

    2015-12-01

    Full Text Available ABSTRACT Disposal of Umbilical Cord Blood Units due to microbial contamination is a major problem in Cord Blood Banks worldwide as it reduces the number of units available for transplantation. Additionally, economic losses are generated as result of resources and infrastructure used to obtain such units. Umbilical Cord Blood Units that showed initial microbial contamination were subject to strains isolation, identification, and characterization by sequencing the 16S rRNA gene and Enterobacterial Repetitive Intergenic Consensus (ERIC-PCR. Moreover, tests of antimicrobial resistance/sensitivity and phenotypic activities that may play an important role in microbial infection were performed. Microbial contamination was detected in 120 Umbilical Cord Blood Units (2.31% in the period from 2003 to 2013. The most frequently isolated strains were Enterococcus faecium, followed by Staphylococcus epidermidis, Escherichia coli, Enterococcus faecalis, Staphylococcus haemoliticus, Klebsiella pneumoniae, Enterococcus durans, Lactobacillus helveticus, Enterococcus hiriae and Roseomonas genomospecies 5. The ERIC-PCR assays revealed a wide genetic diversity in some strains although belonging to the same genus and specie, indicating different sources of contamination. Broad-spectrum penicillins, third generation cephalosporins, aminoglycosides, and fluoroquinolones showed lower inhibitory activity on the tested strains. All strains were proteolytic, 67.69% were amylase-positive, 27.6% hemolysis-positive, and 34.71% nuclease-positive. The most common sources of contamination were: vaginal flora, digestive tract, and skin flora, highlighting the need for staff training in good manufacturing practices in collection SCU since all contaminants identified are part of the microbial flora of the donors. Implications and consequences in the therapeutic use of Umbilical Cord Blood Units for transplantation contaminated by multiresistant bacteria in immunocompromised

  10. Broken Umbilical Vein Catheter as an Embolus in a Neonate- An Unusual Preventable Complication

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    Anjan Kumar Dhua

    2013-10-01

    Full Text Available Umbilical vein catheter (UVC is used in managing critically sick neonates all over the world. It is generally considered to be safe although various complications can arise and are well known. Herein we describe a successful retrieval of a broken and migrated UVC across the heart in a neonate. Pertinent literature regarding rarity of its occurrence and mechanism of occurrence has been touched upon to prevent such untoward complications.

  11. Ultrasound Assessment of Umbilical Cord Morphology in the First Trimester: A Feasibility Study

    DEFF Research Database (Denmark)

    Narayan, Rajit; Saaid, Rahmah; Pedersen, Lars Henning

    2015-01-01

    Objective: The aim of this study was to determine whether morphology and measurement of the umbilical cord could be accurately assessed at the time of the 11- to 13+6-week scan. Methods: We conducted a prospective study of 100 consecutive women with singleton pregnancies at 11-13+6 weeks' gestation...... be consistently studied in the first trimester. A subjective method of evaluation of the morphology may be a more reproducible technique until measurement strategies are refined and operator experience developed....

  12. Effects of Salvianolic Acid B on Protein Expression in Human Umbilical Vein Endothelial Cells

    OpenAIRE

    Tsong-Min Chang; Guey-Yueh Shi; Hua-Lin Wu; Chieh-Hsi Wu; Yan-Di Su; Hui-Lin Wang; Hsin-Yun Wen; Huey-Chun Huang

    2011-01-01

    Salvianolic acid B (Sal B), a pure water-soluble compound extracted from Radix Salviae miltiorrhizae, has been reported to possess potential cardioprotective efficacy. To identify proteins or pathways by which Sal B might exert its protective activities on the cardiovascular system, two-dimensional gel electrophoresis-based comparative proteomics was performed, and proteins altered in their expression level after Sal B treatment were identified by MALDI-TOF MS/MS. Human umbilical vein endothe...

  13. STUDY OF MORPHOLOGICAL VARIATIONS OF 50 PLACENTAE WITH UMBILICAL CORDS AND ITS DEVELOPMENTAL RELEVANCE

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    Asra Anjum

    2015-09-01

    Full Text Available Introduction: The word “Placenta” is a Latin word and the Greek equivalent word is “Plakons” which means “Flat cake on a plate”. The placenta is a complex multifunctional organ. It provides nutrition, gas exchange, waste removal, endocrine function and immune support. Placenta is a special circulating system to the developing foetus. Being an organ of vital importance for continuation of pregnancy and foetal nutrition it has evolved great interest among the anatomists, embryologists, pathologists and obstetricians. Materials and Methods: The study was done in 50 placentae which were collected from the department of Obstetrics and Gynaecology in collaboration with the department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, Telangana, during the period of 2 years. The morphological variations of placenta, the size, shape, weight and attachment of umbilical cord with its blood vessels were observed, recorded and photographed. The prime objective of the study is to compare and evaluate the morphological alterations of placenta and umbilical cord in pregnancy. Results and Conclusion: In the current study, the majority of the placentae showed round shape, few placentae with oval and irregular and with an accessory lobe in single placenta. The current study also includes variations in insertion of umbilical cords was eccentric in majority, central, marginal and velamentous in a few. Pregnancy induced hypertension significantly affects the placenta by reducing weight and it does not have any significant effect on the shape of placenta, umbilical cord insertion and number of cotyledons on maternal surface. The placenta is the most accurate record of the infants prenatal experience.

  14. Generation of iPSC line epiHUVEC from human umbilical vein endothelial cells

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    Peggy Matz

    2015-11-01

    Full Text Available Human umbilical vein endothelial cells (HUVECs were used to generate the iPSC line epiHUVEC employing a combination of three episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC and KLF4. Pluripotency was confirmed both in vivo and in vitro. The transcriptome profile of epiHUVEC and the human embryonic stem cell line — H1 have a Pearson correlation of 0.899.

  15. Hysteroscopic sterilization with occlusion of sheep uterine tube using n-butyl-2-cyanoacrylate adhesive Esterilização histeroscópica com oclusão da tuba uterina de ovelha com adesivo de n-butil-2-cianoacrilato

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    Sergio Bigolin

    2007-10-01

    Full Text Available PURPOSE: To evaluate the fertility and analyze the macroscopic, microscopic and morphometric aspects of sheep uterine tube sterilization with a hysteroscopically insert of n-butyl-2-cyanoacrylate adhesive. METHODS: 12 adult sheep, with one previous pregnancy, were distributed as follows: group L (n=3 subjected to laparotomy and Pomeroy uterine tube ligation, group S (n=3 subjected to hysteroscopic application of saline solution in tube isthmus and group AD(n=6, that was subjected to hysteroscopic application of 0.5 ml of n-2-butil-cyanoacrylate in tube isthmus. They were mated with fertile males for ninety days. The non pregnant sheep, at the 90th day, were subjected to laparotomy with uterus and tubes uterine resection. The fragments of uterine tubes were fixated in 10% formalin and processes for histology evaluated, and slices dyes for H.E. Data were evaluated by Wilcoxon and Mann-Whitney and Fisher's exact test. RESULTS: All sheep from groups L and AD did not get pregnant (0% in contrast with sheep from group S (100%; the adhesive remained integral in the uterine tube lumen. The percentual of adherences (66.6% and fibrosis responses (100% was significantly higher in the group L than group AD (0% (pOBJETIVO: Avaliar a fertilidade e aspectos macroscópicos, microscópicos e morfométricos da esterilização histeroscópica de tubas uterinas de ovelhas com o adesivo de n-butil-2-cianoacrilato. MÉTODOS: 12 ovelhas adultas, com uma prenhez anterior, foram distribuídas como segue: o grupo L (n=3 submetidas à laparotomia e laqueadura tipo Pomeroy, grupo S (n=3 submetidas à aplicação histeroscópica de solução salina no istmo tubário e grupo AD (n=6, com aplicação histeroscópica de 0,5 ml de cianoacrilato. As ovelhas foram acasaladas com machos de comprovada fertilidade por noventa dias. As ovelhas não prenhes aos 90 dias, foram submetidas à laparotomia com ressecção do útero e tubas uterinas, que foram fixadas em formalina 10%s e os

  16. Lipoabdominoplastia con desinserción umbilical y despegamiento abdominal reducido Lipoabdominoplastia com desinserção umbilical e descolamento reduzido Lipoabdominoplasty with umbilical detachment and reduced abdominal undermining

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    F. A. M. Cido Carvalho

    2008-12-01

    Full Text Available Presentamos una combinación de procedimientos quirúrgicos para el tratamiento del exceso de volumen abdominal con flacidez moderada, utilizando una miniabdominoplastia con despegamiento y desinserción umbilical, asociada a liposucción. La indicación de la técnica se restringe a aquellos casos en los que la liposucción aislada provocaría un agravamiento de la flacidez, mientras que una abdominoplastia clásica implicaría una resección exagerada de piel o la necesidad de dejar una pequeña cicatriz vertical. Una miniabdominplastia trataría solamente la flacidez del abdomen inferior, dejando un exceso de piel en la región supraumbilical. La combinación de liposucción amplia y despegamiento controlado del área central del abdomen, asociada a una desinserción umbilical y su posterior reinserción unos 2 a 4 cm más abajo, nos permite lograr una completa plicatura de los rectos abdominales, con una buena resección del exceso cutáneo del abdomen inferior, además de un tratamiento adecuado de la flacidez moderada del abdomen superior.We present a combination of procedures for the treatment of the abdominal volume excess with moderate skin excess, using lipoabdominoplasty with detachment of the navel. Indications are restricted to those cases where the isolated suction-assisted lipoctomy (SAL would take to the worsening of the skin flaccidity, while the full abdominoplasty would imply in exaggerated excision of the skin or presence of small vertical scar. The miniabdominoplasty more frequently used would only treat the flaccidity about the inferior abdomen, leaving skin excess in the upper abdomen area. The combination of wide suctionassisted lipectomy with undermining in the central area of the abdomen, with umbilical detachment and its posterior new implantation about 2 to 5 cm lower, allows a complete plication of the abdominal rectums, with good excision of the skin excess of the inferior abdomen, besides the treatment of the

  17. Prospective Observational Study of Single-Site Multiport Per-umbilical Laparoscopic Endosurgery versus Conventional Multiport Laparoscopic Cholecystectomy: Critical Appraisal of a Unique Umbilical Approach

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    Priyadarshan Anand Jategaonkar

    2014-01-01

    Full Text Available Purpose. This prospective observational study compares an innovative approach of Single-Site Multi-Port Per-umbilical Laparoscopic Endo-surgery (SSMPPLE cholecystectomy with the gold standard—Conventional Multi-port Laparoscopic Cholecystectomy (CMLC—to assess the feasibility and efficacy of the former. Methods. In all, 646 patients were studied. SSMPPLE cholecystectomy utilized three ports inserted through three independent mini-incisions at the umbilicus. Only the day-to-day rigid laparoscopic instruments were used in all cases. The SSMPPLE cholecystectomy group had 320 patients and the CMLC group had 326 patients. The outcomes were statistically compared. Results. SSMPPLE cholecystectomy had average operative time of 43.8 min and blood loss of 9.4 mL. Their duration of hospitalization was 1.3 days (range, 1–5. Six patients (1.9% of this group were converted to CMLC. Eleven patients had controlled gallbladder perforations at dissection. The Visual Analogue Scores for pain on postoperative days 0 and 7, the operative time, and the scar grades were significantly better for SSMPPLE than CMLC. However, umbilical sepsis and seroma outcomes were similar. We had no bile-duct injuries or port-site hernias in this study. Conclusion. SSMPPLE cholecystectomy approach complies with the principles of laparoscopic triangulation; it seems feasible and safe method of minimally invasive cholecystectomy. Overall, it has a potential to emerge as an economically viable alternative to single-port surgery.

  18. Osteogenic potential of human umbilical cord-derived mesenchymal stromal cells cultured with umbilical cord blood-derived fibrin: a preliminary study.

    Science.gov (United States)

    Baba, Kyoko; Yamazaki, Yasuharu; Ishiguro, Masashi; Kumazawa, Kenichi; Aoyagi, Kazuya; Ikemoto, Shigehiro; Takeda, Akira; Uchinuma, Eiju

    2013-12-01

    This study examined the potential for osteogenesis via regenerative medicine using autologous tissues (umbilical cord (UC) and umbilical cord blood (UCB)) in nude mice. The study was designed to provide the three elements required for regenerative medicine (cell, scaffold, and growth factor) and autoserum for culture by means of autologous tissues. Mesenchymal stromal cells were obtained from UC (UC-MSCs). Fibrin, platelet-rich-plasma, and autoserum were obtained from UCB as scaffold, growth factor and serum for culture respectively. UC-MSCs were obtained from Wharton jelly and cultured with UCB-derived fibrin (UCB-fibrin) for 3-4 weeks to induce their differentiation into osteoblasts. They were implanted subcutaneously into the dorsum of male nude mice for 6 weeks prior to undergoing assessment. The assessments performed were haematoxylin and eosin, and alizarin red staining, immunohistochemical staining of human mitochondria, scanning electron microscopy, scanning electron microscopy with energy dispersive X-ray spectrometry and real-time reverse transcriptase-polymerase chain reaction to assess the expressions of osteoblast markers. Consequently, the differentiation of UC-MSCs into osteoblasts and the production of hydroxyapatite were verified. This study suggested the possible formation of bone tissue using biomedical materials obtained from UC and UCB.

  19. Regulation of uterine and umbilical amino acid uptakes by maternal amino acid concentrations.

    Science.gov (United States)

    Thureen, P J; Anderson, S M; Hay, W W

    2000-09-01

    We tested the hypothesis that decreased fetal amino acid (AA) supply, produced by maternal hypoaminoacidemia (low AA) during hyperglycemia (HG), is reversible with maternal AA infusion and regulates fetal insulin concentration ([I]). We measured net uterine and umbilical AA uptakes during maternal HG/low AA concentration ([AA]) and after maternal intravenous infusion of a mixed AA solution. After 5 days HG, all maternal [AA] except glycine were decreased >50%, particularly essential [AA] (P infusion increased net uterine uptakes of Val, Leu, Ile, Met, and Ser and net umbilical uptakes of Val, Leu, Ile, Met, Phe, and Arg but did not change net uteroplacental uptake of any AA. Fetal [I] increased 55 +/- 14%, P < 0.001, with correction of fetal [AA], despite the lack of change in fetal glucose concentration. Thus generalized maternal hypoaminoacidemia decreases uterine and umbilical uptakes of primarily the essential AA and decreases fetal branched-chain [AA]. These changes are reversed with correction of maternal [AA], which also increases fetal [I].

  20. Effects of static magnetic field on human umbilical vessel endothelial cell

    Institute of Scientific and Technical Information of China (English)

    LI Fei; XU Ke-wei; WANG Hai-chang; GUO Wen-yi; HAN Yong; LIU Bing; ZHANG Rong-qing

    2007-01-01

    Objective:To investigate the effects of static magnetic field(SMF) on the viability,adhesion molecule expression of human umbilical vessel endothelial cell.Methods:Magnetic flux intensity was 0.1 mT,1 mT,10 mT.Cell viability and proliferation were measured with 3H-TdR and MTT methods; and apoptosis of human umbilical vein endothelial cell (HUVEC) was studied by flow cytometry and transmission electric microscopy.ELISA was used to measure the expression of ICAM-1 and VCAM-1 on endothelium.Results:0.1 mT SMF had no effects on the growth of HUVEC,however,SMF of 1 mT,10 mT attenuated growth of HUVEC.10 mT static magnetic field could induce apoptosis and necrosis of HUVEC.10 mT SMF enhanced the expression of ICAM-1 and VCAM-1 on endothelium.Conclusion:The effect of SMF depends on the intensity of SMF.10 mT SMF has adverse effects on human umbilical vessel endothelial cell.

  1. The value of ultrasonography in the diagnosis of portal vein thrombosis by umbilical venous catheterization

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kwang Keun; Kim, Young Tong; Kim, Il Young [Chonan Hospital, Soonchunhyang University, Chonan (Korea, Republic of)

    2000-12-15

    To evaluate the usefulness of ultrasonography for diagnosis of portal vein thrombosis (PVT) associated with the umbilical venous catheterization (UVC). We reviewed the abnormal ultrasonography of 54 patients with UVC. We observed echogenic thrombus in the portal vein by ultrasonography which has a 5-10 MHz linear transducer. We evaluated the frequency of PVT, the relationship between PVT and duration of UVC, and the location of catheter tip (Group I (n=41): above the diaphragm, Group II (n=9): between the diaphragm and the liver, Group III (n=4): below the liver), the location of thrombus on US, and the change of PVT on the follow-up ultrasonography. PVT was identified in the 7 neonates (13%) among the 54 neonates with UVC. The frequency of PVT was 5% on group I, 45% on group II and 25% on group III. The 6 cases among the 7 cases(86%) of PVT were localized to the umbilical portion of the left portal vein, and there were completely resolved (n=4) or regressed (n=1) on the follow-up ultrasonography(n=5). Remaining one case of PVT was located in the right, left, and main portal veins with collateral formation, and cavernous transformation occurred on the follow-up. Most PVTs by UVC are localized to the umbilical portion of left portal vein. Ultrasonography is a useful modality to diagnose PVT by UVC.

  2. Influence of the Umbilical Cord Insertion Site on the Optimal Individual Birth Weight Achievement

    Directory of Open Access Journals (Sweden)

    Sophie Brouillet

    2014-01-01

    Full Text Available Study Question. To determine whether the umbilical cord insertion site of singleton pregnancies could be linked to the newborn birth weight at term and its individual growth potential achievement. Material and Methods. A cohort study including 528 records of term neonates was performed. Each neonate was assessed for growth adjusted for gestational age according to the infant’s growth potential using the AUDIPOG module. We considered two categories of umbilical cord insertions: central and peripheral. Intrauterine growth restriction was defined as birth weight below the 10th percentile. Statistical analysis was performed using Chi-square, Student’s t test, Wilcoxon test, ANOVA, and logistic regression. Results. We observed a total of 343 centrally inserted cords versus 185 peripheral cords. There were twice as many smokers in the mothers of the peripheral category compared to the centrally inserted ones. More importantly, we demonstrated that only 17/343 (5.0% of infants with central cord insertion were growth restricted, compared to 37/185 (20.0% of the infants born with a peripheral insertion. Neonates with centrally inserted cord were significantly heavier. Conclusion. The umbilical cord insertion site of singleton pregnancies is associated with the newborn’s birth weight at term and its individual growth potential achievement.

  3. Laparoscopic umbilical hernia repair in the presence of extensive paraumbilical collateral veins: a case report.

    Science.gov (United States)

    Lases, Seilenna S; Eker, Hasan H; Pierik, Engelbertus G J M; Klitsie, Pieter J; de Goede, Barry; Peeters, Mark P F M Vrancken; Kazemier, Geert; Lange, Johan F

    2011-12-01

    A patient with an umbilical hernia presenting with collateral veins in the abdominal wall and umbilicus is a case that every hernia surgeon has to deal with occasionally. Several underlying diseases have been described to provoke collateral veins in the abdominal wall. However, the treatment strategy should be uniform. We herein report a case of a successful laparoscopic umbilical hernia repair in a patient with collateral veins in the abdominal wall and umbilicus. A 63-year-old man was referred to the surgical outpatient clinic with a large symptomatic umbilical hernia and collateral veins in the abdominal wall, secondary to an occlusion of both common iliac veins. Because of collateral veins in the umbilicus and the size of the hernial defect, he was offered laparoscopic hernia repair without compromising these veins. Because of the extensive abdominal wall collaterals, duplex sonography vein mapping was performed preoperatively to mark a safe collateral-free area for trocar introduction. The defect was repaired by mesh prosthesis.

  4. Human umbilical cord hyaluronate. Neutral sugar content and carbohydrate-protein linkage studies.

    Science.gov (United States)

    Varma, R; Varma, R S; Allen, W S; Wardi, A H

    1975-07-14

    Paper chromatography of neutral sugars and gas chromatography of their aldononitrile acetates indicated the presence of fucose, arabinose and a small amount of glucose in purified human umbilical cord hyaluronate. The molar ratios of serine, threonine and aspartic acid to neutral sugars were not unity, suggesting the non-involvement of the neutral sugars and the amino acids in a carbohydrate-protein linkage. The same was indicated by an increase in the percentage of the aforementioned amino acids and by the absence of sugar alditols in umbilical cord hyaluronate reduced eith NaBH4 -PdCl2, after alkali treatment. This reduction caused a decrease in the intrinsic viscosity and molecular wieght to about one-half and an appreciable decrease in the specific rota tion of hyaluronate, suggesting a separation of the two antiparallel chains o the double helical hyaluronate. The umbilical cord hyluronate containe contained bound silicon and it is possible that this bound silicon may cross-link the two chains at interspersed intervals through the uronic acid moiety and/or through neutral sugars.

  5. Therapeutic potential of umbilical cord blood cells for type 1 diabetes mellitus.

    Science.gov (United States)

    He, Binbin; Li, Xia; Yu, Haibo; Zhou, Zhiguang

    2015-11-01

    Type 1 diabetes mellitus (T1DM) is a chronic disorder that results from autoimmune-mediated destruction of pancreatic islet β-cells. However, to date, no conventional intervention has successfully treated the disease. The optimal therapeutic method for T1DM should effectively control the autoimmunity, restore immune homeostasis, preserve residual β-cells, reverse β-cell destruction, and protect the regenerated insulin-producing cells against re-attack. Umbilical cord blood is rich in regulatory T (T(reg)) cells and multiple types of stem cells that exhibit immunomodulating potential and hold promise in their ability to restore peripheral tolerance towards pancreatic islet β-cells through remodeling of immune responses and suppression of autoreactive T cells. Recently, reinfusion of autologous umbilical cord blood or immune cells from cord blood has been proposed as a novel therapy for T1DM, with the advantages of no risk to the donors, minimal ethical concerns, a low incidence of graft-versus-host disease and easy accessibility. In this review, we revisit the role of autologous umbilical cord blood or immune cells from cord blood-based applications for the treatment of T1DM.

  6. Short stature with umbilical hernia - Not always due to cretinism: A report of two cases

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    Sharvil S Gadve

    2012-01-01

    Full Text Available A 7-year-old boy presented with umbilical hernia and short stature. Growth retardation, recurrent upper respiratory tract infections and delayed developmental milestones were present from infancy. Umbilical hernia was diagnosed at the age of 5 years. On examination, he had short-trunk dwarfism, large head circumference, coarse facial features, joint stiffness, hepatosplenomegaly, and mild mental retardation. He had normal biochemical parameters, thyroid function tests and arterial blood gas analysis. Radiological evaluation showed that the child had Hunter syndrome with findings of J-shaped sellaturcica, proximal bulleting of metacarpals, spatulated ribs and anterior beaking of lumbar vertebrae. The second case was a 6-year-old girl with umbilical hernia, short stature, normal biochemistry and radiological findings of mucopolysaccharidosis. However, she also had corneal opacity; confirmed by slit-lamp examination, which led to the diagnosis of Hurler-Scheie syndrome. Enzymatic studies could not be done in both the cases, as they are not available at most centers.

  7. Methylmercury level in umbilical cords from patients with congenital Minamata disease.

    Science.gov (United States)

    Harada, M; Akagi, H; Tsuda, T; Kizaki, T; Ohno, H

    1999-08-30

    A total of 151 umbilical cords during the period from 1950 to 1969 were collected from the residents of the Minamata area (including 25 patients with congenital Minamata disease) for methylmercury (MeHg) analysis. When the MeHg discharge from the Chisso Company's Minamata factory into the Minamata Bay is compared with the incidence of congenital Minamata disease, the abrupt increase of the former in 1952 [Nishimura H. Chem. Today 1998;323:60-66] was found to precede that of the latter by approximately 2 years, thereby indicating that MeHg is the cause of the disaster. This was confirmed by the elevated levels of MeHg in the umbilical cords from residents of the Minamata area [from 0.35 +/- 0.30 (S.D.) ppm in 1952 to 0.96 +/- 0.75 ppm in 1955], the MeHg levels (1.60 +/- 1.00 ppm) in the cords from patients with congenital Minamata disease showing the highest values [P Minamata disease (0.72 +/- 0.65 ppm), mental retardation (0.74 +/- 0.64 ppm), other diseases (0.22 +/- 0.15 ppm), and no symptoms (0.28 +/- 0.20 ppm), respectively]. Thus, in order to fill a gap, which extends over a long period of time, in studies on environmental Hg pollution, umbilical cord samples were considered to be a useful tool.

  8. Methods of isolation, expansion, differentiating induction and preservation of human umbilical cord mesenchymal stem cells

    Institute of Scientific and Technical Information of China (English)

    LI Dong-rui; CAI Jian-hui

    2012-01-01

    Objective This literature review aims to summarize the methods of isolation,expansion,differentiation and preservation of human umbilical cord mesenchymal stem cells (hUCMSCs),for comprehensive understanding and practical use in preclinical research and clinical trials.Data sources All the literature reviewed was published over the last 10 years and is listed in PubMed and Chinese National Knowledge Infrastructure (CNKI).Studies were retrieved using the key word "human umbilical cord mesenchymal stem cells".Results Explants culture and enzymatic digestion are two methods to isolate hUCMSCs from WJ and there are modifications to improve these methods.Culture conditions may affect the expansion and differentiating orientations of hUCMSCs.In addition,hUCMSCs can maintain their multi-potential effects after being properly frozen and thawed.Conclusion Considering their multi-potential,convenient and non-invasive accessibility,low immunogenicity and the reported therapeutic effects in several different preclinical animal models,hUCMSCs have immense scope in regeneration medicine as a substitute for MSCs derived from bone marrow or umbilical cord blood.

  9. Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews

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    Cunping Yin

    2016-01-01

    Full Text Available Hindlimb ischemia is still a clinical problem with high morbidity and mortality. Patients suffer from consequent rest pain, ulcers, cool limbs, and even amputation. Angiogenesis is a promising target for the treatment of ischemic limbs, providing extra blood for the ischemic region. In the present study, we investigated the role of umbilical cord-derived mesenchymal stem cells (UC-MSCs in regulating angiogenesis and relieving hindlimb ischemia. UC-MSCs were isolated from the umbilical cord of tree shrews. Angiography results showed that UC-MSCs injection significantly promoted angiogenesis in tree shrews. Moreover, the ankle brachial index, transcutaneous oxygen pressure, blood perfusion, and capillary/muscle fiber ratio were all markedly increased by the application of UC-MSCs. In addition, the conditioned culture of human umbilical vein endothelial cells using medium collected from UC-MSCs showed higher expression of angiogenic markers and improved migration ability. In short, the isolated UC-MSCs notably contributed to restoring blood supply and alleviating the symptoms of limb ischemia through enhancing angiogenesis.

  10. Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews.

    Science.gov (United States)

    Yin, Cunping; Liang, Yuan; Zhang, Jian; Ruan, Guangping; Li, Zian; Pang, Rongqing; Pan, Xinghua

    2016-01-01

    Hindlimb ischemia is still a clinical problem with high morbidity and mortality. Patients suffer from consequent rest pain, ulcers, cool limbs, and even amputation. Angiogenesis is a promising target for the treatment of ischemic limbs, providing extra blood for the ischemic region. In the present study, we investigated the role of umbilical cord-derived mesenchymal stem cells (UC-MSCs) in regulating angiogenesis and relieving hindlimb ischemia. UC-MSCs were isolated from the umbilical cord of tree shrews. Angiography results showed that UC-MSCs injection significantly promoted angiogenesis in tree shrews. Moreover, the ankle brachial index, transcutaneous oxygen pressure, blood perfusion, and capillary/muscle fiber ratio were all markedly increased by the application of UC-MSCs. In addition, the conditioned culture of human umbilical vein endothelial cells using medium collected from UC-MSCs showed higher expression of angiogenic markers and improved migration ability. In short, the isolated UC-MSCs notably contributed to restoring blood supply and alleviating the symptoms of limb ischemia through enhancing angiogenesis.

  11. Reproducibilidad en la lectura de un set de placas de citología cérvico-uterinas en cuatro centros especializados de Medellín, Antioquia / Reproducibility of reading a set of cervical cytology smears in four specialized centers in Medellin, Antioquia

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    Edwin Guevara

    2014-05-01

    Full Text Available Objetivo: evaluar el grado de reproducibilidad en la lectura de placas de citología cérvico-uterina entre cuatro centros de lectura especializados de la ciudad de Medellín, Colombia. Metodología: 181 placas de citología cérvico-uterina provenientes de un estudio de prevalencia de anormalidades citológicas en Pueblorrico, Antioquia, se sometieron a lectura en cuatro centros especializados de Medellín. Se le pidió a cada centro que realizara una lectura rutinaria manteniendo el estudio en ciego por medio de recodificación de las placas, evitando que se filtrara información entre centros. Se calculó la concordancia general y el índice kappa de Fleiss. Resultados: de las 181 placas, sólo en 55 placas los 4 centros concordaron en el resultado, obteniéndose un porcentaje de concordancia global del 30% y un índice kappa global de 0,31. Según la escala de Fleiss, se observó una baja reproducibilidad en la lectura de las placas citológicas entre los cuatro centros involucrados en el estudio. La concordancia por pares de centros presentó índices de kappa entre 0,3 a 0,7. Discusión: existe una alta variabilidad en la interpretación de los resultados citológicos entre los centros estudiados. Es necesario implementar procesos de entrenamiento y unificación de criterios de lecturas de la citología cervical en nuestro medio Objective: to assess the degree of reproducibility in the reading of cervical cytology smears among four specialized reading centers at Medellin, Colombia. Methodology: 181 cervical cytology smears from a study on the prevalence of cytological abnormalities in Pueblorrico, a town located in the southwestern region of the state of Antioquia in Colombia, were re-read by four specialized centers in Medellin. Each center was asked to conduct a blind routine reading of the smears to avoid disclosure of information between centers. The reproducibility was measured by percentage agreement and kappa. Results: of 181 smears

  12. Human umbilical cord Wharton's Jelly-derived mesenchymal stem cells differentiation into nerve-like cells

    Institute of Scientific and Technical Information of China (English)

    MA Lian; FENG Xue-yong; CUI Bing-lin; Frieda Law; JIANG Xue-wu; YANG Li-ye; XIE Qing-dong; HUANG Tian-hua

    2005-01-01

    Background The two most basic properties of mesenchymal stem cells (MSCs) are the capacities to self-renew indefinitely and differentiate into multiple cells and tissue types. The cells from human umbilical cord Wharton's Jelly have properties of MSCs and represent a rich source of primitive cells. This study was conducted to explore the possibility of inducing human umbilical cord Wharton's Jelly-derived MSCs to differentiate into nerve-like cells.Methods MSCs were cultured from the Wharton's Jelly taken from human umbilical cord of babies delivered after full-term normal labor. Salvia miltiorrhiza and β-mercaptoethanol were used to induce the human umbilical cord-derived MSCs to differentiate. The expression of neural protein markers was shown by immunocytochemistry. The induction process was monitored by phase contrast microscopy, electron microscopy (EM), and laser scanning confocal microscopy (LSCM) .The pleiotrophin and nestin genes were measured by reverse transcription-polymerase chain reaction (RT-PCR). Results MSCs in the Wharton's Jelly were easily attainable and could be maintained and expanded in culture. They were positive for markers of MSCs, but negative for markers of hematopoietic cells and graft-versus-host disease (GVHD)-related cells. Treatment with Salvia miltiorrhiza caused Wharton's Jelly cells to undergo profound morphological changes. The induced MSCs developed rounded cell bodies with multiple neurite-like extensions. Eventually they developed processes that formed networks reminiscent of primary cultures of neurons. Salvia miltiorrhiza and β-mercaptoethanol also induced MSCs to express nestin, β-tubulinⅢ, neurofilament (NF) and glial fibrillary acidic protein (GFAP). It was confirmed by RT-PCR that MSCs could express pleiotrophin both before and after induction by Salvia miltiorrhiza. The expression was markedly enhanced after induction and the nestin gene was also expressed.Conclusions MSCs could be isolated from human umbilical

  13. Comparison between mechanical properties of human saphenous vein and umbilical vein

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    Hamedani Borhan

    2012-08-01

    Full Text Available Abstract Background As a main cause of mortality in developed countries, Coronary Artery Disease (CAD is known as silent killer with a considerable cost to be dedicated for its treatment. Coronary Artery Bypass Graft (CABG is a common remedy for CAD for which different blood vessels are used as a detour. There is a lack of knowledge about mechanical properties of human blood vessels used for CABG, and while these properties have a great impact on long-term patency of a CABG. Thus, studying these properties, especially those of human umbilical veins which have not been considered yet, looks utterly necessary. Methods Umbilical vein, as well as human Saphenous vein, are respectively obtained after cesarean and CABG. First, histological tests were performed to investigate different fiber contents of the samples. Having prepared samples carefully, force-displacement results of samples were rendered to real stress–strain measurements and then a fourth-order polynomial was used to prove the non-linear behavior of these two vessels. Results Results were analyzed in two directions, i.e. circumferentially and longitudinally, which then were compared with each other. The comparison between stiffness and elasticity of these veins showed that Saphenous vein’s stiffness is much higher than that of umbilical vein and also, it is less stretchable. Furthermore, for both vessels, longitudinal stiffness was higher than that of circumferential and in stark contrast, stretch ratio in circumferential direction came much higher than longitudinal orientation. Conclusion Blood pressure is very high in the region of aorta, so there should be a stiff blood vessel in this area and previous investigations showed that stiffer vessels would have a better influence on the flow of bypass. To this end, the current study has made an attempt to compare these two blood vessels’ stiffness, finding that Saphenous vein is stiffer than umbilical vein which is somehow as stiff as

  14. CORRELATION OF UMBILICAL CORD LENGTH WITH FOETAL A ND MATERNAL OUTCOME

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    Yadav

    2013-01-01

    Full Text Available ABSTRACT: INTRODUCTION: The cord disposition and length of umbilical cord in the amniotic cavity remain unrecognised till the birth of the ba by.Cord complications remain one of the major causes of foetal death. OBJECTIVES: To study 1. Length of umbilical cord in new-born babies 2. The outcome of pregnancy with abnormal length of umb ilical cord 3. The relation between umbilical cord length and cord abnormalities 4. Relation between umbilical cord abnormalities and pe rinatal outcome METHODS: This study of 200 cases was carried out in S.R.T.R. Medical College, Ambajogai over a period of 6 months from Jan 2011 to Jun 2011. 100 cases belonged to control group (cord length 50-60 cm. Study group had short cord (i.e. c ord length less than 50 cm comprising 20 cases and long cord (i.e. cord length above 60 cm comprising 80 cases. Apgar score at 1 and 5 minutes after birth were recorded. Birth weight and sex of all babies were noted. Number of loops of cord and position noted. Cord loop tight or l oose noted (only for LSCS cases. RESULTS: Maximum numbers of cases were from age group 20-24 years. Parity was not found to affect cord length. Maximum cases (31.25% of fo etal distress were found in group with cord length more than 60 cm. Significantly low APGAR sco re at 5 mins noted in long cord group (15% than control group. Cord length in control and study group in relation to the sex of the foetus was found to be statistically insignificant. 30 cases from long cord group required caesarean section and most of them for foetal distr ess. Cord entanglement (88.75% was the most common complication in long cord group. CONCLUSION: Minimum observed cord length in this study was 28 c m and maximum cord length was 98 cm. There was no relation between mat ernal age, parity, sex of the foetus with the umbilical cord length. Cord abnormalities were obse rved in long cord group only. Higher percentage of caesarean section and perinatal mortali ty was more in long

  15. Grande fístula bilateral da artéria coronária: a escolha do tratamento clínico Gran fístula bilateral de la arteria coronaria: la selección del tratamiento clínico Large bilateral coronary artery fistula: the choice of clinical treatment

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    Luciana Oliveira Cascaes Dourado

    2009-09-01

    Full Text Available Relatamos o caso de um paciente do sexo feminino, assintomática, com grande fístula bilateral da artéria coronária-artéria pulmonar. O monitoramento clínico foi a opção escolhida para tratamento. Discutimos os pormenores das opções terapêuticas, enfatizando a tendência excessiva de utilizar a abordagem cirúrgica e a grande escassez de acompanhamentos clínicos de longo prazo em pacientes assintomáticos.Relatamos el caso de un paciente del sexo femenino, asintomática, con gran fístula bilateral de la arteria coronaria-arteria pulmonar. El monitoreo clínico fue la opción elegida para el tratamiento. Discutimos los pormenores de las opciones terapéuticas, enfatizando la tendencia excesiva de utilizar el abordaje quirúrgico y la gran escasez de seguimientos clínicos de largo plazo en pacientes asintomáticos.

  16. Angiotomografia coronariana multislice na avaliação da origem anômala das artérias coronarianas Angiotomografía coronaria multislice en la evaluación del origen anómalo de las arterias coronarias Multislice coronary angiotomography in the assessment of coronary artery anomalous origin

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    Daniel Rocha Rabelo

    2012-03-01

    Full Text Available Fundamento: A origem anômala das artérias coronarianas é uma entidade relativamente rara, podendo se apresentar de várias formas clínicas e evoluir de forma adversa. A angiotomografia multislice das artérias coronarianas vem ganhando espaço na prática clínica diária, representando importante método propedêutico, com grande potencial na avaliação anatômica dessas artérias. Objetivo: O objetivo deste estudo é descrever os achados angiotomográficos e a evolução de pacientes com origem anômala das artérias coronarianas. Métodos: Durante o período de janeiro de 2008 a março de 2011, foram avaliados consecutivamente 404 pacientes encaminhados para realização de angiotomografia das coronárias por diversos motivos, com tempo médio de seguimento de 21 meses. Resultados: Nove pacientes (2,2% apresentaram origem anômala das artérias coronárias, sendo quatro com origem anômala da artéria circunflexa (Cx em Coronária Direita (CD, dois com origem anômala da CD (um com origem de CD em Cx, e um com origem de CD em seio coronariano esquerdo, um paciente com tronco coronariano único (descendente anterior e Cx saindo do seio coronariano esquerdo, um com trajeto anômalo do tronco da coronária esquerda entre aorta e artéria pulmonar e um paciente apresentando tronco coronariano esquerdo originando-se do seio coronariano direito. Dos pacientes avaliados, um paciente recebeu um cardiodesfibrilador implantável; um paciente evoluiu com morte súbita durante internação hospitalar; e os outros não tiveram intercorrências. Conclusão: A angiotomografia multislice das coronárias representa método propedêutico minimamente invasivo que possibilita detectar a origem, o curso e terminação das anomalias de origem das artérias coronarianas com excelente acurácia, possibilitando o correto diagnóstico e auxiliando no planejamento terapêutico.RESUMEN FUNDAMENTO: El origen anómalo de las arterias coronarias es una entidad

  17. Anomalías congénitas de la arteria aorta: Evaluación mediante tomografía computada multicorte en neonatos y niños Congenital abnormalities of aortic artery: Assessment in neonates and early childhodd with multislice tomography

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    Diego Haberman

    2009-09-01

    Full Text Available Para la evaluación de los defectos congénitos de la arteria aorta, los métodos de imágenes utilizados tradicionalmente son la ecocardiografia y la radiología simple. La angiotomografía computada multicorte aparece como un método de relevancia en el diagnóstico de estas entidades, permitiendo evaluar en forma no invasiva, rápida y precisa las distintas anormalidades, otorgando de esta manera información sumamente útil a los cirujanos cardiovasculares para definir la estrategia quirúrgica. En el presente artículo revisamos las aplicaciones de la angiotomografia computada multicorte en la evaluación de las malformaciones congénitas de la arteria aorta más frecuentes en el periodo neonatal y en la primera infancia.In the evaluation of aortic artery congenital abnormalities, the echocardiography and the plain X ray are the traditionally used imaging methods. Multislice angiotomography appears as an important method in diagnosis of these different diseases allowing evaluate these entities in a non invasive, fast and accurate form, giving to cardiovascular surgeons very important information to delineate the surgical strategy. In this article, we review the applications of multislice angiotomography in the evaluation of most frequent congenital anomalies of aorta artery, performed in neonates and early childhood.

  18. Bupropion therapy during pregnancy: the drug and its major metabolites in umbilical cord plasma and amniotic fluid

    Science.gov (United States)

    FOKINA, Valentina M; WEST, Holly; ONCKEN, Cheryl; CLARK, Shannon M; AHMED, Mahmoud S; HANKINS, Gary DV; NANOVSKAYA, Tatiana N

    2017-01-01

    Background Bupropion is used for treatment of depression during pregnancy. However, its use as a smoking cessation aid for pregnant women is currently under evaluation. Objectives The aim of this opportunistic study was to investigate the transfer of bupropion and its major pharmacologically active metabolites, hydroxybupropion and threohydrobupropion, across the placenta in vivo. In addition, the concentrations of the drug and its metabolites were determined in the amniotic fluid. Methods The following samples were collected at deliveries from twenty-two women taking bupropion: maternal blood (n=22), umbilical cord venous blood (n=22), and amniotic fluid (n=9). The concentrations of the drug and its metabolites in blood plasma and amniotic fluid were determined by means of liquid chromatography-mass spectrometry. Placental passage was calculated as a ratio of umbilical cord venous plasma to maternal plasma concentrations. Results The levels of hydroxybupropion and threohydrobupropion in umbilical cord venous plasma were invariably lower than their corresponding concentrations in maternal plasma. The concentrations of bupropion in umbilical cord plasma were lower than in maternal plasma in the majority of the maternal-cord blood pairs. The median values of the umbilical cord venous plasma to maternal plasma ratios were: bupropion, 0.53 (interquartile range 0.35, n=18), hydroxybupropion, 0.21 (interquartile range 0.12, n=18), and threohydrobupropion, 0.61 (interquartile range 0.11, n=21). In umbilical cord venous plasma, the median concentration of bupropion was 5.3 ng/ml; hydroxybupropion, 103.6 ng/ml and threohydrobupropion, 59.6 ng/ml. Bupropion and its metabolites were detectable in the amniotic fluid but the concentrations of threohydrobupropion were higher than those in the corresponding umbilical cord venous plasma. Conclusion Bupropion and its active metabolites cross the placenta to the fetal circulation. The concentrations of hydroxybupropion and

  19. Processo ensino-aprendizagem da técnica de palpação e mensuração uterina: influência da prática The teaching-learnin process of the uterine measurement and palpation techinique: the influence practice

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    Clarice Heiko Muramatsu

    1996-12-01

    Full Text Available O presente estudo relacionado ao processo ensino-aprendizagem da técnica de palpação e mensuração uterina, teve como objetivos, analisar a influência da prática em relação à habilidade e analisar o conhecimento adquirido da técnica dos estudantes de Graduação em Enfermagem. Aplicando o "modelo padrão" elaborado para este estudo, os estudantes foram avaliados em 2 etapas; os resultados obtidos permitiram concluir pela importância da prática no processo ensino-aprendizagem de uma habilidade perceptivo-motora, verificada através da melhora do desempenho dos estudantes em relação à habilidade e ao conhecimento adquirido.The present study related to the teaching-learning process concerning the uterine measurement and palpation technique, it was intended to analyze the influence practice had on the Undergraduation Nursing students' skills acquired knowledge by the use of that technique. Applying a standard instrument previously developed for this study, the students' evaluation was 'carried out in two phases. The results showed a significant improvement in the students' performance skills and descriptive knowledge. Thus, this study was able to stress the importance of practice for the motorperceptive skills in the teaching-learning process.

  20. Avaliação da cavidade uterina com hístero-sonografia em pacientes com falha de implantação após fertilização in vitro Evaluation of the uterine cavity by sonohysterography in patients with implantation failure after in vitro fertilization

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    Teiichi Ninomiya

    2003-08-01

    Full Text Available OBJETIVO: analisar a acurácia da hístero-sonografia (HSoG na avaliação da cavidade uterina nas pacientes que tiveram falha de implantação na primeira tentativa de fertilização in vitro. MÉTODOS: foram analisadas prospectivamente, em estudo duplo-cego, pacientes previamente submetidas à transferência de pelo menos um embrião e que apresentaram falha de implantação. As pacientes foram submetidas a HSoG e em seguida a histeroscopia diagnóstica, realizadas por equipes diferentes, não havendo troca de informações sobre os resultados das mesmas. Os resultados foram agrupados e interpretados somente após o término da pesquisa. A HSoG foi realizada após cateterização do colo uterino por sonda uretral nº 8 e injeção de soro fisiológico. A interface anecóica proporcionada pela solução salina permite determinar as anormalidades, tais como pólipos uterinos ou miomas submucosos. A histeroscopia diagnóstica foi realizada com equipamento Karl Storz, óptica rígida de 4 mm a 30°, e distensão da cavidade uterina com soro fisiológico. Não utilizou-se anestesia local nem houve a necessidade de realizar dilatação cervical. RESULTADOS: foram estudadas 28 pacientes das 33 inicialmente selecionadas para o presente estudo. A HSoG diagnosticou anormalidades em 8 pacientes, sendo que em cinco pacientes foram encontrados pólipos endometriais (62,5%, pólipos endocervicais em duas pacientes (25,0% e mioma submucoso em uma (12,5%. A histeroscopia (padrão-ouro diagnosticou alterações em 7 pacientes, sendo que em duas pacientes (28,6% foram encontrados pólipos endometriais, em outras duas pacientes (28,6% pólipos cervicais e em uma paciente, mioma submucoso (14,2%. A HSoG, quando comparada com a histeroscopia diagnóstica, apresentou sensibilidade de 71,4%, especificidade de 85,7%, valor preditivo positivo de 62,5% e valor preditivo negativo de 90%. CONCLUSÕES: por apresentar valor preditivo positivo baixo, todas as vezes que a

  1. Alterações histoquímicas das glicosaminoglicanas na cérvice uterina no final da prenhez da rata albina após ministração local de hialuronidase Histochemical changes of the glycosaminoglycans in the uterine cervix of pregnant rats after local injection of hyaluronidase

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    Viviane Almeida de Alcântara Lopes

    2008-07-01

    Full Text Available OBJETIVO: estudar as alterações histoquímicas relacionadas às glicosaminoglicanas da cérvice uterina da rata albina, após ministração local de hialuronidase no final da prenhez. MÉTODOS: dez ratas com teste de prenhez positivo foram distribuídas aleatoriamente em dois grupos, numericamente iguais. O Grupo Controle (Gc foi constituído pelas ratas que receberam 1 mL de água destilada, dose única, no 18º dia da prenhez, sob anestesia, ministrado na cérvice uterina. O Grupo Experimental (Gex constou de ratas que receberam, sob as mesmas condições do Gc, 0,02 mL de hialuronidase, diluído em 0,98 mL de água destilada (total de 1 mL. No 20º dia de prenhez, as ratas foram novamente anestesiadas e submetidas à dissecção, preparando-se a cérvice uterina para estudo histoquímico com coloração de alcian blue e seus bloqueios (pH=0,5, pH=2,5, metilação e saponificação. RESULTADOS: verificou-se na lâmina própria no Gc, reação fortemente positiva (+3 e, no Gex, reação negativa, na coloração de alcian blue no pH=0,5. Em pH=2,5 a coloração também se apresentou fortemente positiva (+4 no Gc e fracamente positiva (+1 no Gex. Após metilação, tanto o Gc quanto o Gex mostraram reação negativa após coloração de alcian blue no pH=2,5. Com a reação de metilação seguida de saponificação e na digestão enzimática em lâmina, a coloração da lâmina própria se mostrou negativa em ambos os grupos. CONCLUSÕES: há uma nítida predominância de glicosaminoglicanas sulfatadas no Gc em relação ao Gex e uma tênue quantidade de glicosaminoglicanas carboxiladas identificadas no Gex. As modificações evidenciadas na matriz extracelular sugerem que a hialuronidase injetada localmente na cérvix uterina promoveu alterações bioquímicas compatíveis com maturação cervical.PURPOSE: to study the histochemical changes related to the uterine cervix glycosaminoglycan of the albino female rat, after local ministration of

  2. Amino acid composition of parturient plasma, the intervillous space of the placenta and the umbilical vein of term newborn infants

    Directory of Open Access Journals (Sweden)

    J.S. Camelo Jr.

    2004-05-01

    Full Text Available The objective of the present study was to determine the levels of amino acids in maternal plasma, placental intervillous space and fetal umbilical vein in order to identify the similarities and differences in amino acid levels in these compartments of 15 term newborns from normal pregnancies and deliveries. All amino acids, except tryptophan, were present in at least 186% higher concentrations in the intervillous space than in maternal venous blood, with the difference being statistically significant. This result contradicted the initial hypothesis of the study that the plasma amino acid levels in the placental intervillous space should be similar to those of maternal plasma. When the maternal venous compartment was compared with the umbilical vein, we observed values 103% higher on the fetal side which is compatible with currently accepted mechanisms of active amino acid transport. Amino acid levels of the placental intervillous space were similar to the values of the umbilical vein except for proline, glycine and aspartic acid, whose levels were significantly higher than fetal umbilical vein levels (average 107% higher. The elevated levels of the intervillous space are compatible with syncytiotrophoblast activity, which maintain high concentrations of free amino acids inside syncytiotrophoblast cells, permitting asymmetric efflux or active transport from the trophoblast cells to the blood in the intervillous space. The plasma amino acid levels in the umbilical vein of term newborns probably may be used as a standard of local normality for clinical studies of amino acid profiles.

  3. Endothelial Nitric Oxide Synthase Traffic Inducer in the Umbilical Vessels of the Patients with Pre-eclampsia

    Institute of Scientific and Technical Information of China (English)

    Wenpei XIANG; Hanping CHEN; Lian HU; Xiaoyan XU

    2009-01-01

    The expression of endothelial nitric oxide synthase traffic inducer (NOSTRIN) was examined in the umbilical vessels of the patients with pre-eclampsia (PE) to explore its possible role in the pathogenesis of PE.The NOSTRIN mRNA in umbilical tissues was determined by RT-PCR.The eNOS activity in umbilical vessels was spectrophotometrically detected.NO2-/NO3-,the stable metabolic end products of NO,was measured by using nitrate reductase.RT-PCR showed that the expression level of NOSTRIN was significantly higher in women with PE than in the normal group (P<0.01).The activity of eNOS was significantly decreased in PE group [(12.83±3.61) U/mg] than in normal group [(21.72±3.83) U/mg] (P<0.01).The level of NO2-/NO3- in PE patients (27.53± 7.48) μmol/mg was significantly lower than that of normal group (54.27±9.53) μmol/mg (P<0.01).The significant negative correlation existed between the expression of NOSTRIN and the activity of eNOS in umbilical vessels of women with PE (r=-0.58,P<0.01).It was concluded that the level of NOSTRIN expression was increased in umbilical vessel of women with PE,indicating that it may be involved in the pathogenesis of PE.

  4. Human umbilical cord blood-derived mesenchymal stem cells promote regeneration of crush-injured rat sciatic nerves

    Institute of Scientific and Technical Information of China (English)

    Mi-Ae Sung; Jong-Ho Lee; Hun Jong Jung; Jung-Woo Lee; Jin-Yong Lee; Kang-Mi Pang; Sang Bae Yoo; Mohammad S. Alrashdan; Soung-Min Kim; Jeong Won Jahng

    2012-01-01

    Several studies have demonstrated that human umbilical cord blood-derived mesenchymal stem cells can promote neural regeneration following brain injury. However, the therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells in guiding peripheral nerve regeneration remain poorly understood. This study was designed to investigate the effects of human umbilical cord blood-derived mesenchymal stem cells on neural regeneration using a rat sciatic nerve crush injury model. Human umbilical cord blood-derived mesenchymal stem cells (1 × 106) or a PBS control were injected into the crush-injured segment of the sciatic nerve. Four weeks after cell injection, brain-derived neurotrophic factor and tyrosine kinase receptor B mRNA expression at the lesion site was increased in comparison to control. Furthermore, sciatic function index, Fluoro Gold-labeled neuron counts and axon density were also significantly increased when compared with control. Our results indicate that human umbilical cord blood-derived mesenchymal stem cells promote the functional recovery of crush-injured sciatic nerves.

  5. Effect of Magnesium Sulfate on Doppler Parameters of Fetal Umbilical and Middle Cerebral Arteries in Women with Severe Preeclampsia

    Directory of Open Access Journals (Sweden)

    Nazanin Farshchian

    2012-01-01

    Full Text Available Objective: To assess the effect of injecting magnesium sulfate on Doppler parameters of fetal umbilical and middle cerebral arteries (MCA in women with severe preeclampsia. Materials and Methods: A total of 21 patients with severe preeclampsia admitted to Imam Reza Hospital, Kermanshah (Iran, were evaluated. Before and after administration of magnesium sulfate, Doppler ultrasound scan was carried out to measure fetal middle cerebral artery and umbilical artery blood flow. Paired t-test was used for statistical analysis. Results: After injection of magnesium sulfate, the mean resistivity index (RI-umbilical, and pulsatility index (PI-cerebral showed a statistically significant reduction ( P < 0.001. The cerebroumbilical C/U ratio increased after the intervention ( P < 0.001. The PI-umbilical ( P = 0.1 and pre- and post-RI-cerebral ( P = 0.96 did not have statistically significant changes. Conclusions: Infusion of magnesium sulfate significantly decreases the flow in the fetus RI-umbilical and PI-MCA, and it increases C/U ratio indices in color Doppler ultrasound.

  6. Ultrastructural characterization of bovine umbilical cord blood cells Caracterização ultra-estrutural das células sanguíneas do cordão umbilical bovino

    Directory of Open Access Journals (Sweden)

    Gustavo C Rodrigues

    2010-10-01

    Full Text Available The umbilical cord blood (UCB is an important source of pluripotent stem cells, which motivated researches on ontogeny and transplantation. The morphological characterization of umbilical cord cells is the first step to establish subsequent experiments on these areas. Although some information on humans can be found, no data on UCB is available for bovines. Therefore, this work is the first attempt to conduct an ultrastructural characterization of bovine umbilical cord blood. Blood was collected from the umbilical cord of twenty fetuses by punction of the umbilical vein. Samples were processed for whole leucocytes observation by centrifugation and the buffy coat was collected. Cells were washed and pelleted and prepared according to the standard protocol of the transmission electron microscopy. The presence of cells with morphologic characteristics compatible with the precursors from the erythrocytic, neutrophilic, eosinophilic, basophilic, and lymphocytic lineages was observed. Atypical cells with peculiar morphological features, strongly similar to apoptotic cells, were seen. Bovine neutrophils with three types of cytoplasmic granules were also found in the blood. The ultrastructural characteristics of observed bovine UCB cells where similar to those found in other species, suggesting that bovines could possibly constitute an experimental model for approaches on UCB cells research.O sangue de cordão umbilical (SCU é uma importante fonte de células progenitoras pluripotentes, que motiva pesquisas em ontogenia e transplantes. A caracterização morfológica das células de cordão umbilical é o primeiro passo para se estabelecer experimentos subsequentes nessas áreas. Embora algumas informações sobre SCU em humanos possam ser encontradas, não existe nenhuma informação disponível sobre elas em bovinos. Portanto, este trabalho é a primeira tentativa de se conduzir uma caracterização ultra-estrutural do sangue de cordão umbilical

  7. 腹腔镜脐环缝扎术治疗小儿脐疝的体会%Laparoscopic suture of umbilical ring in treatment of umbilical hernia in children

    Institute of Scientific and Technical Information of China (English)

    石群峰

    2012-01-01

    Objective-.To explore the effect of laparoscopic suture of umbilical ring in treatment of umbilical hernia in children. Methods: The clinical data of 21 children with umbilical hernia treaied with laparoscopie suture of umbilical ring were retrospectively analyzed. Results: All 21 procedures were performed successfully. The mean operative time was 32.5 min (20-45 min). There was no blood loss during surgery. The postoperative recovery was rapid. During the follow-up from 6 to 72 months in 18 cases.no recurrence or operative complication was recorded. Conclusions; Laparoscopie suture of umbilical ring in treatment of umbilical hernia in children is a safe and feasible procedure with better mini-invasive and cosmetic effect.%目的:探讨腹腔镜脐环缝扎术治疗小儿脐疝的临床疗效.方法:回顾分析为21例脐疝患儿行腹腔镜脐环缝扎术的临床资料.结果:21例手术均获成功.手术时间20 ~45 min,平均32.5 min;术中均无出血,术后康复快.术后18例患儿随访6 ~72个月,无复发或肠粘连、肠梗阻等并发症发生.结论:腹腔镜脐环缝扎术治疗小儿脐疝安全、有效,手术微创、美观,值得推广应用.

  8. Umbilical cord blood testosterone and childhood internalizing and externalizing behavior: a prospective study.

    Directory of Open Access Journals (Sweden)

    Monique Robinson

    Full Text Available Antenatal testosterone exposure influences fetal neurodevelopment and gender-role behavior in postnatal life and may contribute to differences in developmental psychopathology during childhood. We prospectively measured the associations between umbilical cord blood testosterone levels at birth and childhood behavioral development in both males and females from a large population based sample. The study comprised 430 females and 429 males from the Western Australian Pregnancy Cohort (Raine Study where umbilical cord blood had been collected. Total testosterone concentrations were determined by mass spectrometry and bioavailable testosterone (BioT levels were calculated. At two, five, eight and ten years of age, the participants completed the Child Behavior Checklist (CBCL. Linear regression models were used to analyse the relationship between BioT concentrations (in quartiles and CBCL scores (total, internalizing, externalizing and selected syndrome. Boys had higher mean CBCL T-scores than girls across all ages of follow-up. There was no significant relationship between cord blood BioT quartiles and CBCL total, internalizing and externalizing T-scores at age two or five to ten combined. In the syndrome score analyses, higher BioT quartiles were associated with significantly lower scores for attention problems for boys at age five, eight and ten, and greater withdrawal symptoms in pre-school girls (age five. We did not identify a consistent relationship between antenatal testosterone exposure and total, internalizing or externalizing behavioral difficulties in childhood. Higher umbilical cord BioT levels were associated with lower scores for attention problems in boys up to 10 years and more withdrawn behavior in 5-year-old girls; however, these findings were not consistent across ages and require further investigation in a larger sample.

  9. Bovine tunica vaginalis: a new material for umbilical hernioplasty in sheep

    Directory of Open Access Journals (Sweden)

    B. T. Abass

    2008-01-01

    Full Text Available In this study, fresh patches of bovine tunica vaginalis (BTV, was used as implants for the repair of experimentally-created umbilical hernias in eight sheep. The scrotum were harvested immediately after slaughter and thoroughly washed with sterile distilled water for 5-7 times. The scrotal skin together with the fatty tissues and the loose connective tissues and the tunica adventitia were mechanically stripped by means of a sterile surgical knife, and finally washed with sterile physiological saline solution for 5-7 times. The prepared patches were immersed in the sterile saline solution and preserved at 2-4 ºC in sterile jars, ready for use within 4 hrs from their harvesting for hernioplasty of sheep umbilical hernias. The eight implanted grafts were examined clinically and histologically, and all were successfully healed except one (87.5%. Clinically, the successfully implanted BTV patches didn't show signs of rejection, except for the presence of cardinal signs of local inflammatory reaction which were subsided 48 hrs post-operation, and disappeared within 4-5 days post-operation. The healing processes showed no significant abnormalities, except for the occurrence of a few simple multifocal stitch abscess infections. The histopathological examinations showed invasion of dense fibrous connective tissues, consisted of heavy bundles of collagen fibers, through which newly formed capillaries and mononuclear inflammatory cells and melanin pigments deposition, were infiltrated through the graft. As a first report on this new tissue implant in sheep, BTV is proved to be a suitable biocompatible heterogenic surgical patch for reconstruction of umbilical hernias, because of its availability as a cheap tissue, with a high tensile strength and flexibility. However, further investigation is required regarding preservation efficiency and employment for reconstruction of soft tissue defects in man and animals.

  10. Differentiation of human umbilical cord mesenchymal stem cells into dermal fibroblasts in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Han, Yanfu [Department of Burn and Plastic Surgery, Burns Institute, First Hospital Affiliated to General Hospital of PLA, Beijing (China); Chai, Jiake, E-mail: cjk304@126.com [Department of Burn and Plastic Surgery, Burns Institute, First Hospital Affiliated to General Hospital of PLA, Beijing (China); Sun, Tianjun; Li, Dongjie; Tao, Ran [Department of Burn and Plastic Surgery, Burns Institute, First Hospital Affiliated to General Hospital of PLA, Beijing (China)

    2011-10-07

    Highlights: {yields} Mesenchymal stem cells (MSCs) are potential seed cells for tissue-engineered skin. {yields} Tissue-derived umbilical cord MSCs (UCMSCs) can readily be isolated in vitro. {yields} We induce UCMSCs to differentiate into dermal fibroblasts via conditioned medium. {yields} Collagen type I and collagen type III mRNA level was higher in differentiated cells. {yields} UCMSCs-derived fibroblast-like cells strongly express fibroblast-specific protein. -- Abstract: Tissue-derived umbilical cord mesenchymal stem cells (UCMSCs) can be readily obtained, avoid ethical or moral constraints, and show excellent pluripotency and proliferation potential. UCMSCs are considered to be a promising source of stem cells in regenerative medicine. In this study, we collected newborn umbilical cord tissue under sterile conditions and isolated UCMSCs through a tissue attachment method. UCMSC cell surface markers were examined using flow cytometry. On the third passage, UCMSCs were induced to differentiate into dermal fibroblasts in conditioned induction media. The induction results were detected using immunofluorescence with a fibroblast-specific monoclonal antibody and real time PCR for type I and type III collagen. UCMSCs exhibited a fibroblast-like morphology and reached 90% confluency 14 to 18 days after primary culture. Cultured UCMSCs showed strong positive staining for CD73, CD29, CD44, CD105, and HLA-I, but not CD34, CD45, CD31, or HLA-DR. After differentiation, immunostaining for collagen type I, type III, fibroblast-specific protein, vimentin, and desmin were all strongly positive in induced cells, and staining was weak or negative in non-induced cells; total transcript production of collagen type I and collagen type III mRNA was higher in induced cells than in non-induced cells. These results demonstrate that UCMSCs can be induced to differentiate into fibroblasts with conditioned induction media and, in turn, could be used as seed cells for tissue

  11. Effect of maternal activity during gestation on maternal behavior, fetal growth, umbilical blood flow, and farrowing characteristics in pigs.

    Science.gov (United States)

    Harris, E K; Berg, E P; Berg, E L; Vonnahme, K A

    2013-02-01

    Yorkshire gilts either remained in their individual stall from d 40 to term (CON; n = 7) or were subjected to exercise for 30 min 3 times per week from mid to late gestation (EX; n = 7) to determine the impact of increased maternal activity during gestation on maternal behavior, fetal growth, umbilical blood flow, and parturition. In parity 1, maternal body composition (10th rib back fat and LM area), maternal behavior, and farrowing characteristics were recorded. In parities 1 and 2, fetal growth, fetal heart rate, pulsatility index and resistance index, and umbilical blood flow were monitored beginning at d 39 of gestation continuing to d 81 of gestation. Exercise continued until d 104. Gilts allowed to exercise sat less (P gestation in the pig increased umbilical blood flow and appeared to reduce maternal restlessness, impacts on offspring development in postnatal life are not known.

  12. Development of composite fiber-optic electric-power umbilical cable and optical feedthrough for deep ocean mining

    Science.gov (United States)

    Mitsui, T.; Gomi, T.; Ito, T.; Ushitani, S.; Yamaguchi, M.

    The development of mining systems for mineral resources from deep ocean floors is now progressing in many countries. In Japan, the Agency of Industrial Science and Technology, has conducted research and development for a manganese nodule mining system. In this project, it is planned to use a new composite fiber-optic electric power umbilical cable for electrical power and control signal transmission from a main vessel to subsea equipment such as lifting pumps and collecting devices at about 5,000 meters' depth. The umbilical cable system is required to have good resistance to repetitive bending, twisting, and other external forces and to be able to withstand water pressure of up to 550kgf/sq cm. A 100m long sample umbilical cable, electrical connectors, and optical feedthroughs for this system have been developed and successfully passed mechanical, electrical, and optical tests.

  13. Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

    Directory of Open Access Journals (Sweden)

    Claire Mennan

    2013-01-01

    Full Text Available Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs sourced from several different cord regions, including artery, vein, cord lining, and Wharton’s jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics.

  14. Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord

    Science.gov (United States)

    Wright, Karina; Bhattacharjee, Atanu; Balain, Birender; Richardson, James; Roberts, Sally

    2013-01-01

    Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, including artery, vein, cord lining, and Wharton's jelly, are described in the literature. However, no one study has yet isolated and characterised MSCs from all regions of the same cord to determine the most suitable cells for cell based therapeutics. PMID:23984420

  15. Differentiation of human umbilical cord blood stem cells into hepatocytes in vivo and in vitro

    Institute of Scientific and Technical Information of China (English)

    Xiao-Peng Tang; Min Zhang; Xu Yang; Li-Min Chen; Yang Zeng

    2006-01-01

    AIM: To study the condition and potentiality of human umbilical cord blood stem cells (HUCBSC) to differentiate into hepatocytes in vivo or in vitro.METHODS: In a cell culture study of human umbilical cord blood stem cell (HUCBSC) differentiation, human umbilical cord blood mononuclear cells (HUCBMNC) were separated by density gradient centrifugation.Fibroblast growth factor (FGF) and hepatocyte growth factor (HGF) and the supernatant of fetal liver were added in the inducing groups. Only FGF was added in the control group. The expansion and differentiation of HUCBMNC in each group were observed. Human alpha fetoprotein (AFP) and albumin (ALB) were detected by immunohistochemistry. In the animal experiments, the survival SD rats with acute hepatic injury after carbon tetrachloride (CCL4) injection 48 h were randomly divided into three groups. The rats in group A were treated with human umbilical cord blood serum. The rats in group B were treated with HUCBMNC transplantation. The rats in group C were treated with HUCBMNC transplantation followed by intraperitoneal cyclophosphamide for 7 d.The rats were killed at different time points after the treatment and the liver tissue was histopathologically studied and human AFP and ALB detected by immunohistochemistry. The human X inactive-specific transcript gene fragment in the liver tissue was amplified by PCR to find human DNA.RESULTS: The results of cell culture showed that adherent cells were stained negative for AFP or ALB in control group. However, the adherent cells in the inducing groups stained positive for AFP or ALB. The result of animal experiment showed that no human AFP or ALB positive cells present in the liver tissue of group A (control group). However, many human AFP or ALB positive cells were scattered around sinus hepaticus and the central veins of hepatic lobules and in the portal area in group B and group C after one month. The fragment of human X chromagene could be detected in the liver tissue of

  16. Instrumented ultrasonic PIG (Pipeline Inspection Gauge) using free swimming and online umbilical fiber glass cable technologies

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Paulo [A. Hak Brasil Servicos Industriais Ltda, Belo Horizonte, MG (Brazil); Prins, Tom [A. Hak Industrial Services B.V., Geldermalsen (Netherlands)

    2009-07-01

    This technical document presents the world-patented Piglet{sup R} inspection system developed by A. Hak Industrial Services BV. A tool which combines the advantages of the 'free swimming' and the 'umbilical' data acquisition, eliminating the disadvantages of both. This system is suitable for passing small radius bends, mitred-bends, back-to back bends, and can travel on bi-directional way. Furthermore, in this technical document we present a recent development about Marker Detection System, which allows a highly accurate and real-time pig track system. (author)

  17. Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks

    Directory of Open Access Journals (Sweden)

    Polchow Bianca

    2012-05-01

    Full Text Available Abstract Background In vitro fabricated tissue engineered vascular constructs could provide an alternative to conventional substitutes. A crucial factor for tissue engineering of vascular constructs is an appropriate cell source. Vascular cells from the human umbilical cord can be directly isolated and cryopreserved until needed. Currently no cell bank for human vascular cells is available. Therefore, the establishment of a future human vascular cell bank conforming to good manufacturing practice (GMP conditions is desirable for therapeutic applications such as tissue engineered cardiovascular constructs. Materials and methods A fundamental step was the adaption of conventional research and development starting materials to GMP compliant starting materials. Human umbilical cord artery derived cells (HUCAC and human umbilical vein endothelial cells (HUVEC were isolated, cultivated, cryopreserved (short- and long-term directly after primary culture and recultivated subsequently. Cell viability, expression of cellular markers and proliferation potential of fresh and cryopreserved cells were studied using trypan blue staining, flow cytometry analysis, immunofluorescence staining and proliferation assays. Statistical analyses were performed using Student’s t-test. Results Sufficient numbers of isolated cells with acceptable viabilities and homogenous expression of cellular markers confirmed that the isolation procedure was successful using GMP compliant starting materials. The influence of cryopreservation was marginal, because cryopreserved cells mostly maintain phenotypic and functional characteristics similar to those of fresh cells. Phenotypic studies revealed that fresh cultivated and cryopreserved HUCAC were positive for alpha smooth muscle actin, CD90, CD105, CD73, CD29, CD44, CD166 and negative for smoothelin. HUVEC expressed CD31, CD146, CD105 and CD144 but not alpha smooth muscle actin. Functional analysis demonstrated acceptable

  18. Long-term recurrence and chronic pain after repair for small umbilical or epigastric hernias

    DEFF Research Database (Denmark)

    Christoffersen, Mette W; Helgstrand, Frederik; Rosenberg, Jacob;

    2015-01-01

    and risk of chronic pain in small primary ventral hernias. METHODS: A cohort study with questionnaire and clinical follow-up was conducted. Patients with primary, elective, open mesh or sutured repair for a small umbilical or epigastric hernia (≤ 2 cm) were included. RESULTS: One thousand three hundred......BACKGROUND: Mesh repair reduces the risk of reoperation for recurrence in patients with primary ventral hernias. However, reoperation for recurrence underestimates total recurrence (reoperation + clinical) and mesh reinforcement may induce chronic pain. This study investigated the total recurrence......-term risk of recurrence after repair for small ventral hernias without increased risk of chronic pain....

  19. SUSCEPTIBILITY LOCI FOR UMBILICAL HERNIA IN SWINE DETECTED BY GENOME-WIDE ASSOCIATION.

    Science.gov (United States)

    Liao, X J; Lia, L; Zhang, Z Y; Long, Y; Yang, B; Ruan, G R; Su, Y; Ai, H S; Zhang, W C; Deng, W Y; Xiao, S J; Ren, J; Ding, N S; Huang, L S

    2015-10-01

    Umbilical hernia (UH) is a complex disorder caused by both genetic and environmental factors. UH brings animal welfare problems and severe economic loss to the pig industry. Until now, the genetic basis of UH is poorly understood. The high-density 60K porcine SNP array enables the rapid application of genome-wide association study (GWAS) to identify genetic loci for phenotypic traits at genome wide scale in pigs. The objective of this research was to identify susceptibility loci for swine umbilical hernia using the GWAS approach. We genotyped 478 piglets from 142 families representing three Western commercial breeds with the Illumina PorcineSNP60 BeadChip. Then significant SNPs were detected by GWAS using ROADTRIPS (Robust Association-Detection Test for Related Individuals with Population Substructure) software base on a Bonferroni corrected threshold (P = 1.67E-06) or suggestive threshold (P = 3.34E-05) and false discovery rate (FDR = 0.05). After quality control, 29,924 qualified SNPs and 472 piglets were used for GWAS. Two suggestive loci predisposing to pig UH were identified at 44.25MB on SSC2 (rs81358018, P = 3.34E-06, FDR = 0.049933) and at 45.90MB on SSC17 (rs81479278, P = 3.30E-06, FDR = 0.049933) in Duroc population, respectively. And no SNP was detected to be associated with pig UH at significant level in neither Landrace nor Large White population. Furthermore, we carried out a meta-analysis in the combined pure-breed population containing all the 472 piglets. rs81479278 (P = 1.16E-06, FDR = 0.022475) was identified to associate with pig UH at genome-wide significant level. SRC was characterized as plausible candidate gene for susceptibility to pig UH according to its genomic position and biological functions. To our knowledge, this study gives the first description of GWAS identifying susceptibility loci for umbilical hernia in pigs. Our findings provide deeper insights to the genetic architecture of umbilical hernia in pigs.

  20. IMPACT OF MECHANICAL MYOCARDIAL INJURY PRODUCTS, LPS AND THEIR COMBINATION ON HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS

    Directory of Open Access Journals (Sweden)

    V. G. Matveeva

    2014-01-01

    Full Text Available Complicated systemic inflammatory response (SIR often determines the outcome in patients after cardiac surgery. Systemic endothelial activation plays the most important role in SIR pathogenesis. We have studied the impact of mechanical myocardial injury products, LPS and their combination on human umbilical vein endothelial cells (HUVEC. We have found that HUVEC increase the production of proinflammatory cytokines in response tocardiomyocyte cytosolic fraction responsible for mechanical injury modeling. 2% cytosolic fraction containing 0.204 ng/mL of Hsp70 was a greater stimulus for endothelial cells to produce IL-6 and IL8 than moderateendotoxin concentrations.

  1. Development of the Orion Crew-Service Module Umbilical Retention and Release Mechanism

    Science.gov (United States)

    Delap, Damon C.; Glidden, Joel Micah; Lamoreaux, Christopher

    2013-01-01

    The Orion CSM umbilical retention and release mechanism supports and protects all of the cross-module commodities between the spacecrafts crew and service modules. These commodities include explosive transfer lines, wiring for power and data, and flexible hoses for ground purge and life support systems. The mechanism employs a single separation interface which is retained with pyrotechnically actuated separation bolts and supports roughly two dozen electrical and fluid connectors. When module separation is commanded, either for nominal on-orbit CONOPS or in the event of an abort, the mechanism must release the separation interface and sever all commodity connections within milliseconds of command receipt. There are a number of unique and novel aspects of the design solution developed by the Orion mechanisms team. The design is highly modular and can easily be adapted to other vehiclesmodules and alternate commodity sets. It will be flight tested during Orions Exploration Flight Test 1 (EFT-1) in 2014, and the Orion team anticipates reuse of the design for all future missions. The design packages fluid, electrical, and ordnance disconnects in a single separation interface. It supports abort separations even in cases where aerodynamic loading prevents the deployment of the umbilical arm. Unlike the Apollo CSM umbilical which was a destructive separation device, the Orion design is resettable and flight units can be tested for separation performance prior to flight.Initial development testing of the mechanisms separation interface resulted in binding failures due to connector misalignments. The separation interface was redesigned with a robust linear guide system, and the connector separation and boom deployment were separated into two discretely sequenced events. These changes addressed the root cause of the binding failure by providing better control of connector alignment. The new design was tuned and validated analytically via Monte Carlo simulation. The

  2. Thrombopoietin concentration in umbilical cord blood of healthy term newborns is higher than in adult controls.

    Science.gov (United States)

    Walka, M M; Sonntag, J; Dudenhausen, J W; Obladen, M

    1999-01-01

    Thrombopoietin (TPO) concentrations were determined in umbilical cord plasma of 121 healthy term newborns. The lower detection limit of the enzyme immunoassay employed was 32.5 pg/ml. Median cord plasma TPO concentration was 78 (interquartile range 55-107) pg/ml. 95th percentile was 255 pg/ml. In only 8% (10/121), TPO was below the detection limit compared to 81% of healthy adults (25/31). In cord blood and adult controls, there were no significant correlations of TPO with platelet count or mass.

  3. Evaluation of antenatal umbilical coiling index at 16-21 weeks of gestation as a predictor of trisomy 21 and other chromosomal defects

    NARCIS (Netherlands)

    Verkleij, C.P.; Oppen, A.C. van; Mulder, E.J.H.; Laat, M.W. de; Sikkel, E.; Koster, M.P.; Tweel, I. van de; Franx, A.; Visser, G.H.

    2013-01-01

    OBJECTIVES: To determine whether there is an association between sonographically assessed hyper- or hypocoiling of the umbilical cord and the presence of trisomy 21, to provide reference values for the antenatal umbilical coiling index (aUCI) at a gestational age of 16-21 weeks and to determine whet

  4. Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes

    DEFF Research Database (Denmark)

    Smith, Julie; Halse, Karen G; Damm, Peter;

    2013-01-01

    To examine concentrations of three cardiovascular propeptides in umbilical cord plasma of neonates born to mothers with Type 1, Type 2 and gestational diabetes. Measurement of cardiovascular markers in umbilical cord plasma may potentially help identify neonates at risk of postnatal complications...

  5. Clinical Experience in Successful Rescue of 2 Cases of Prolapse of Umbilical Cord%脐带脱垂抢救成功2例报告

    Institute of Scientific and Technical Information of China (English)

    潘晓陆

    2015-01-01

    The rupture of membranes, umbilical cord prolapse in cervical outlets, umbilical cord prolapse. Membranes unsolved, the umbilical cord is located in the presentation side or front says invisible umbilical cord prolapse or umbilical cord presentation. Great harm to the fetus umbilical cord prolapse, because of the contractions squeezed between umbilical cord in the dew in the basin wal , umbilical cord blood circulation caused by blocked, fetal hypoxia, severe intrauterine distress, such as the blood flow completely blocked, the fetus can quickly suf ocation death.%胎膜破裂,脐带脱出于宫颈口外者,称脐带脱垂。胎膜未破,而脐带位于先露旁侧或前方者称隐性脐带脱垂或脐带先露。脐带脱垂对胎儿危害极大,因宫缩时脐带在先露于盆壁之间受挤压,致脐带血液循环受阻,胎儿缺氧,发生严重的宫内窘迫,如血流完全阻断,胎儿可迅速窒息死亡。

  6. Longitudinal study of aortic isthmus Doppler in appropriately grown and small-for-gestational-age fetuses with normal and abnormal umbilical artery Doppler.

    LENUS (Irish Health Repository)

    Kennelly, M M

    2012-04-01

    To establish reference ranges using longitudinal data for aortic isthmus (AoI) Doppler indices in appropriate-for-gestational-age (AGA) fetuses and to document the longitudinal trends in a cohort of small-for-gestational-age (SGA) fetuses with normal umbilical artery Doppler and in fetuses with intrauterine growth restriction (IUGR) and abnormal umbilical artery Doppler.

  7. Local perceptions, cultural beliefs and practices that shape umbilical cord care: a qualitative study in Southern Province, Zambia.

    Directory of Open Access Journals (Sweden)

    Julie M Herlihy

    Full Text Available BACKGROUND: Global policy regarding optimal umbilical cord care to prevent neonatal illness is an active discussion among researchers and policy makers. In preparation for a large cluster-randomized control trial to measure the impact of 4% chlorhexidine as an umbilical wash versus dry cord care on neonatal mortality in Southern Province, Zambia, we performed a qualitative study to determine local perceptions of cord health and illness and the cultural belief system that shapes umbilical cord care knowledge, attitudes, and practices. METHODS AND FINDINGS: This study consisted of 36 focus group discussions with breastfeeding mothers, grandmothers, and traditional birth attendants, and 42 in-depth interviews with key community informants. Semi-structured field guides were used to lead discussions and interviews at urban and rural sites. A wide variation in knowledge, beliefs, and practices surrounding cord care was discovered. For home deliveries, cords were cut with non-sterile razor blades or local grass. Cord applications included drying agents (e.g., charcoal, baby powder, dust, lubricating agents (e.g., Vaseline, cooking oil, used motor oil and agents intended for medicinal/protective purposes (e.g., breast milk, cow dung, chicken feces. Concerns regarding the length of time until cord detachment were universally expressed. Blood clots in the umbilical cord, bulongo-longo, were perceived to foreshadow neonatal illness. Management of bulongo-longo or infected umbilical cords included multiple traditional remedies and treatment at government health centers. CONCLUSION: Umbilical cord care practices and beliefs were diverse. Dry cord care, as recommended by the World Health Organization at the time of the study, is not widely practiced in Southern Province, Zambia. A cultural health systems model that depicts all stakeholders is proposed as an approach for policy makers and program implementers to work synergistically with existing cultural

  8. An Umbilical/Paraumbilical Hernia as a Sign of an Intraabdominal Malignancy in the Elderly

    Directory of Open Access Journals (Sweden)

    Kenig Jakub

    2014-04-01

    Full Text Available The umbilical area can present with a variety of signs associated with an intra abdominal malignancy. An umbilical/paraumbilical hernia might itself be a sign of an internal malignancy. The correlation between the presence of an umbilical/paraumbilical hernia and an intra abdominal malignancy has been previously based only on case reports. The aim of the study was to evaluate the significance of an umbilical/paraumbilical hernia as a symptom of an intraabdominal malignancy. Material and methods. A retrospective analysis was performed; review of the medical records of 145 patients (113 female and 32 male; mean age 66.4±11.9 with an umbilical/paraumbilical hernia treated during the period of 2005-2013. Twenty-three patients (15.9% were diagnosed with an intra abdominal malignancy; 34% were in the age group over 75 years of age. Results. The most common malignancies were: colorectal cancer, followed by pancreatic cancer, and cancers of the adnexa and kidneys. The patients with a concomitant malignancy identified were significantly older than those without a malignancy. In 65% of patients, the diagnosis was made postoperatively. Logistic regression analysis demonstrated that age, the presence of preoperative symptoms, anemia, and weight loss were independent risk factors for concomitant abdominal cancer. Conclusion. The findings of this study support intensive preoperative diagnostic evaluation of elderly patients that are qualified for surgery for an umbilical/paraumbilical hernia. This is particularly important because most of these patients had a small/medium hernia orifice, which did not allow for accurate manual abdominal exploration. Currently, the routine preoperative diagnostic evaluation is often insufficient for an accurate diagnosis

  9. Neutrophil killing of human umbilical vein endothelial cells is oxygen radical-mediated and enhanced by TNF-. alpha

    Energy Technology Data Exchange (ETDEWEB)

    Dame, M.K.; Varani, J.; Weinberg, J.M.; Ward, P.A. (Univ. of Michigan, Ann Arbor (United States))

    1991-03-11

    Human umbilical vein endothelial cells are sensitive to killing by activated human neutrophils. Killing is inhibited in the presence of catalase and deferoxamine mesylate but not soybean trypsin inhibitor. Reagent hydrogen peroxide can substitute for activated neutrophils in producing endothelial cell injury. These data suggest that lethal injury is due to the production of oxygen radicals by activated neutrophils. In these respects, the human umbilical vein endothelial cells are similar to rat pulmonary artery endothelial cells in that pretreatment with TNF-{alpha} increases sensitivity to injury by activated neutrophils. In part, the increased endothelial cell sensitivity to killing by neutrophils may be due to up-regulation of surface adhesion molecules. However, it was observed that cells passaged more than two times in culture did not demonstrate increased killing after treatment with TNF-{alpha} while up-regulation of neutrophil adhesion could be detected through several additional passages. Although the human umbilical vein endothelial cells are qualitatively similar to rat pulmonary artery endothelial cells in their sensitivity to killing, they are quantitatively much more resistant. What accounts for the relative resistance of the human umbilical vein endothelial cells is not fully understood. In the rat pulmonary artery endothelial cells, killing is known to be dependent on an intraendothelial source of iron. Pre-treatment of the human umbilical vein endothelial cells with 8-hydroxyquinoline-bound iron increased their sensitivity to oxidant injury. These data suggest that the availability of iron within the human umbilical vein endothelial cells may be a limiting factor in sensitivity to oxygen radical-mediated injury.

  10. Closure of the abdominal wall at the umbilicus and the development of umbilical hernias in a group of foals from birth to 11 months of age.

    Science.gov (United States)

    Enzerink, E; van Weeren, P R; van der Velden, M A

    2000-07-08

    The closure of the body wall defect at the umbilicus was studied in relation to the development of umbilical hernias in a group of 44 normal foals, 25 of which were followed from birth until five months of age, and 19 from birth until 11 months of age. At birth, 19 of the foals had a defect in the body wall at the umbilicus that was termed a 'palpable umbilical ring'. In 18 of them this defect disappeared within four days, but in the other the ring did not close and a hernial sac with abdominal contents was palpable. This foal was considered to be the only foal to have a truly congenital umbilical hernia. Twelve foals developed an umbilical hernia between five and eight weeks of age. The prevalence of umbilical hernias was much higher than in other studies, possibly owing to the prospective nature of the study.

  11. Percutaneous suturing technique and single-site umbilical laparoscopic repair of a Morgagni hernia: Review of three cases.

    Science.gov (United States)

    Zouari, M; Jallouli, M; Bendhaou, M; Zitouni, H; Mhiri, R

    2015-12-01

    Morgagni hernias are uncommon, accounting for only 1-2% of all congenital diaphragmatic hernia. Minimally invasive surgery is today the gold standard treatment. We present a technique using percutaneous suturing and single-site umbilical laparoscopic repair of Morgagni hernia in three children. Recovery was uneventful in all three patients. There was no recurrence and the chest radiograph remained normal during the postoperative follow-up. The percutaneous suturing technique and single-site umbilical laparoscopic repair of a Morgagni hernia is an easy and effective alternative to standard laparoscopic repair.

  12. EXPERIENCIA COMUNICACIONAL EN EL DIAGNÓSTICO Y MANEJO ANTENATAL DE NUDO DEL CORDÓN UMBILICAL

    OpenAIRE

    Hasbun H,Jorge; Muñoz C,Hugo; Sepúlveda L.,Waldo

    2010-01-01

    Se comunica caso clínico de una madre que consulta en semana 31 de gestación por ausencia de movimientos fetales, y cuyo ultrasonido (US) con escala de grises, Doppler color y tridimensional (3D), demostró imágenes altamente sugerentes de nudo verdadero de cordón umbilical. Se efectuó vigilancia con prueba de movimientos fetales diaria, monitoreo electrónico, hemodinamia fetal y umbilical con doppler, alternados cada tres días, durante siete semanas, demostrando bienestar fetal. Se efectuó op...

  13. Congenital hernia of the umbilical cord associated with extracelomic colonic atresia and perforation of gut in a newborn

    Directory of Open Access Journals (Sweden)

    Kamalesh Pal

    2014-01-01

    Full Text Available Congenital hernia of the umbilical cord (CHUC is a rare congenital entity compared to more common post-natally occurring umbilical hernia. Although recognized as a distinct entity since 1920s, CHUC is often misdiagnosed as a small omphalocele, resulting in its underreporting. We present the first case report of CHUC associated with extracelomic colonic atresia, complicated by perinatal perforation in a newborn. We also discuss the differentiating features from other anterior abdominal wall defects such as omphalocele and gastroschisis including its embryogenesis.

  14. Randomized Clinical Trial on the postoperative use of an abdominal binder after laparoscopic umbilical and epigastric hernia repair

    DEFF Research Database (Denmark)

    Christoffersen, Mette; Olsen, B H; Rosenberg, J;

    2015-01-01

    -reducing effect of an abdominal binder in patients undergoing laparoscopic umbilical or epigastric hernia repair. METHODS: Based on power analysis, a minimum of 54 patients undergoing laparoscopic umbilical and epigastric hernia repair were to be included. Patients were randomized to abdominal binders vs......PURPOSE: Application of an abdominal binder is often part of a standard postoperative regimen after ventral hernia repair to reduce pain and seroma formation. However, there is lack of evidence of the clinical effects. The aim of the present study was to investigate the pain- and seroma...

  15. Human Umbilical Cord Blood Serum: Effective Substitute of Fetal Bovine Serum for Culturing of Human Multipotent Mesenchymal Stromal Cells.

    Science.gov (United States)

    Romanov, Yu A; Balashova, E E; Volgina, N E; Kabaeva, N V; Dugina, T N; Sukhikh, G T

    2017-02-01

    Optimal conditions for culturing of multipotent mesenchymal stromal cells in the presence of pooled umbilical cord blood serum were determined. It was found that umbilical cord blood serum in a concentration range of 1-10% effectively supported high viability and proliferative activity of cells with unaltered phenotype and preserved multilineage differentiation capacity. The proposed approach allows avoiding the use of xenogenic animal sera for culturing of multipotent mesenchymal stromal cells and creates prerequisites for designing and manufacturing safe cellular and/or acellular products for medical purposes.

  16. Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells

    OpenAIRE

    2012-01-01

    Carbon monoxide (CO) is a vasoactive molecule that is generated by vascular cells as a byproduct of heme catabolism and it plays an important physiological role in circulation system. In order to investigate whether exogenous CO can mediate the growth and proliferation of vascular cells, in this study, we used 250 parts per million (ppm) of CO to treat human umbilical artery smooth muscle cell (hUASMC) and human umbilical vein endothelial cell (HuVEC) and further evaluated the growth and apop...

  17. Factores maternos y de transporte que condicionan la calidad de las unidades de sangre de cordón umbilical

    OpenAIRE

    Ponce Verdugo, Laura

    2010-01-01

    La Sangre de Cordón Umbilical (SCU), representa una fuente de progenitores hematopoyéticos cada vez más empleada en los procedimientos de trasplante. Sin embargo, la calidad de las unidades consideradas como aptas para ser utilizados, es altamente variable. Algunas circunstancias relacionadas con la recogida de la muestra y su transporte al Banco de Sangre de Cordón Umbilical (BSCU), donde será procesado, pueden influir en sus características finales. Es un tema relativamente reciente con gra...

  18. Que técnica usar nos cuidados ao cordão umbilical do recém-nascido

    OpenAIRE

    Correia, Teresa; Pires, Catarina S. M.

    2016-01-01

    O Enfermeiro Especialista de Saúde Materna, Obstétrica e Ginecológica possui competências com responsabilidade em diversas áreas de atividade. É durante o puerpério que o Enfermeiro cuida do recém-nascido de forma a promover o bem-estar e potenciar a sua saúde, incluindo os cuidados ao coto umbilical. Estes cuidados foram, ao longo dos anos, sofrendo alterações significativas devido ao impacto das infeções do coto umbilical na mortalidade neonatal. Parece existirem diferentes prátic...

  19. Influência intergeracional no cuidado do coto umbilical do recém-nascido

    Directory of Open Access Journals (Sweden)

    Eliane Fonseca Linhares

    2012-01-01

    Full Text Available El estudio objetivó conocer las interrelaciones generacionales que interfieren en el cuidado del cordón umbilical del recién nacido. Investigación descriptiva, de abordaje cualitativo, fundamentado en la Teoría de la Diversidad y Universalidad del Cuidado Cultural, realizada en Jequié-Bahia, con 29 sujetos, siendo 10 madres y 19 cuidadores familiares. Los datos fueron recolectados a través de entrevistas semi-estructuradas y con observación participante subvencionada por diario de campo. Los datos fueron sometidos a análisis de contenido. Los resultados mostraron la influencia de los valores culturales en el sistema familiar intergeneracional, en proceso de cuidar, promoviendo los riesgos de enfermedades referentes a prácticas populares de cuidados al cordón umbilical. Así, las acciones educativas necesitan considerar el contexto cultural de los sujetos involucrados, promoviendo la congruencia entre los saberes populares y científicos.

  20. Label-Free Imaging of Umbilical Cord Tissue Morphology and Explant-Derived Cells

    Science.gov (United States)

    Paesen, Rik; Gyselaers, Wilfried; Stinissen, Piet

    2016-01-01

    In situ detection of MSCs remains difficult and warrants additional methods to aid with their characterization in vivo. Two-photon confocal laser scanning microscopy (TPM) and second harmonic generation (SHG) could fill this gap. Both techniques enable the detection of cells and extracellular structures, based on intrinsic properties of the specific tissue and intracellular molecules under optical irradiation. TPM imaging and SHG imaging have been used for label-free monitoring of stem cells differentiation, assessment of their behavior in biocompatible scaffolds, and even cell tracking in vivo. In this study, we show that TPM and SHG can accurately depict the umbilical cord architecture and visualize individual cells both in situ and during culture initiation, without the use of exogenously applied labels. In combination with nuclear DNA staining, we observed a variance in fluorescent intensity in the vessel walls. In addition, antibody staining showed differences in Oct4, αSMA, vimentin, and ALDH1A1 expression in situ, indicating functional differences among the umbilical cord cell populations. In future research, marker-free imaging can be of great added value to the current antigen-based staining methods for describing tissue structures and for the identification of progenitor cells in their tissue of origin. PMID:27746820