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Sample records for arrester beds

  1. Chemically Mediated Arrestment of the Bed Bug, Cimex lectularius, by Volatiles Associated with Exuviae of Conspecifics

    Science.gov (United States)

    Choe, Dong-Hwan; Park, Hoeun; Vo, Claudia; Knyshov, Alexander

    2016-01-01

    Extracts of the exuviae (cast skins) of nymphal bed bugs (Cimex lectularius) were analyzed for volatile compounds that might contribute to arrestment of adult bed bugs. Four volatile aldehydes, (E)-2-hexenal, 4-oxo-(E)-2-hexenal, (E)-2-octenal, and 4-oxo-(E)-2-octenal were consistently detected in the headspace of freshly shed exuviae regardless of the developmental stages from which the exuviae were obtained. Quantification of the aldehydes in the solvent extracts of homogenized fresh, 45- or 99-d aged 5th instar exuviae indicated that the aldehydes are present in the exuviae and dissipate over time, through evaporation or degradation. Microscopic observation of the fifth instar exuviae indicated that the dorsal abdominal glands on the exuviae maintained their pocket-like structures with gland reservoirs, within which the aldehydes might be retained. Two-choice olfactometer studies with the volatiles from exuviae or a synthetic blend mimicking the volatiles indicated that adult bed bugs tend to settle close to sources of the aldehydes. Our results imply that the presence and accumulation of bed bug exuviae and the aldehydes volatilizing from the exuviae might mediate bed bugs’ interaction with their microhabitats. PMID:27434044

  2. Chemically Mediated Arrestment of the Bed Bug, Cimex lectularius, by Volatiles Associated with Exuviae of Conspecifics.

    Directory of Open Access Journals (Sweden)

    Dong-Hwan Choe

    Full Text Available Extracts of the exuviae (cast skins of nymphal bed bugs (Cimex lectularius were analyzed for volatile compounds that might contribute to arrestment of adult bed bugs. Four volatile aldehydes, (E-2-hexenal, 4-oxo-(E-2-hexenal, (E-2-octenal, and 4-oxo-(E-2-octenal were consistently detected in the headspace of freshly shed exuviae regardless of the developmental stages from which the exuviae were obtained. Quantification of the aldehydes in the solvent extracts of homogenized fresh, 45- or 99-d aged 5th instar exuviae indicated that the aldehydes are present in the exuviae and dissipate over time, through evaporation or degradation. Microscopic observation of the fifth instar exuviae indicated that the dorsal abdominal glands on the exuviae maintained their pocket-like structures with gland reservoirs, within which the aldehydes might be retained. Two-choice olfactometer studies with the volatiles from exuviae or a synthetic blend mimicking the volatiles indicated that adult bed bugs tend to settle close to sources of the aldehydes. Our results imply that the presence and accumulation of bed bug exuviae and the aldehydes volatilizing from the exuviae might mediate bed bugs' interaction with their microhabitats.

  3. Chemically Mediated Arrestment of the Bed Bug, Cimex lectularius, by Volatiles Associated with Exuviae of Conspecifics.

    Science.gov (United States)

    Choe, Dong-Hwan; Park, Hoeun; Vo, Claudia; Knyshov, Alexander

    2016-01-01

    Extracts of the exuviae (cast skins) of nymphal bed bugs (Cimex lectularius) were analyzed for volatile compounds that might contribute to arrestment of adult bed bugs. Four volatile aldehydes, (E)-2-hexenal, 4-oxo-(E)-2-hexenal, (E)-2-octenal, and 4-oxo-(E)-2-octenal were consistently detected in the headspace of freshly shed exuviae regardless of the developmental stages from which the exuviae were obtained. Quantification of the aldehydes in the solvent extracts of homogenized fresh, 45- or 99-d aged 5th instar exuviae indicated that the aldehydes are present in the exuviae and dissipate over time, through evaporation or degradation. Microscopic observation of the fifth instar exuviae indicated that the dorsal abdominal glands on the exuviae maintained their pocket-like structures with gland reservoirs, within which the aldehydes might be retained. Two-choice olfactometer studies with the volatiles from exuviae or a synthetic blend mimicking the volatiles indicated that adult bed bugs tend to settle close to sources of the aldehydes. Our results imply that the presence and accumulation of bed bug exuviae and the aldehydes volatilizing from the exuviae might mediate bed bugs' interaction with their microhabitats. PMID:27434044

  4. Cardiac arrest

    Science.gov (United States)

    ... Article.jsp. Accessed June 16, 2014. Myerburg RJ, Castellanos A. Approach to cardiac arrest and life-threatening ... PA: Elsevier Saunders; 2011:chap 63. Myerburg RJ, Castellanos A. Cardiac arrest and audden aardiac death. In: ...

  5. Daily Arrests

    Data.gov (United States)

    Montgomery County of Maryland — This dataset provides the public with arrest information from the Montgomery County Central Processing Unit (CPU) systems. The data presented is derived from every...

  6. [Heart arrest].

    Science.gov (United States)

    Chiarella, F; Giovannini, E; Bozzano, A; Caristo, G; Delise, P; Fedele, F; Fera, M S; Lavalle, C; Roghi, A; Valagussa, F

    2001-03-01

    Cardiac arrest is one of the leading causes of mortality in industrialized countries and is mainly due to ischemic heart disease. According to ISTAT estimates, approximately 45,000 sudden deaths occur annually in Italy whereas according to the World Health Organization, its incidence is 1 per 1000 persons. The most common cause of cardiac arrest is ventricular fibrillation due to an acute ischemic episode. During acute ischemia the onset of a ventricular tachyarrhythmia is sudden, unpredictable and often irreversible and lethal. Each minute that passes, the probability that the patient survives decreases by 10%. For this reason, the first 10 min are considered to be priceless for an efficacious first aid. The possibility of survival depends on the presence of witnesses, on the heart rhythm and on the resolution of the arrhythmia. In the majority of cases, the latter is possible by means of electrical defibrillation followed by the reestablishment of systolic function. An increase in equipment alone does not suffice for efficacious handling of cardiac arrest occurring outside the hospital premises. Above all, an adequate intervention strategy is required. Ambulance personnel must be well trained and capable of intervening rapidly, possibly within the first 5 min. The key to success lies in the diffusion and proper use of defibrillators. The availability of new generation instruments, the external automatic defibrillators, encourages their widespread use. On the territory, these emergencies are the responsibility of the 118 organization based, according to the characteristics specific to each country, on the regulated coordination between the operative command, the crews and the first-aid means. Strategies for the handling of these emergencies within hospitals have been proposed by the Conference of Bethesda and tend to guarantee an efficacious resuscitation with a maximum latency of 2 min between cardiac arrest and the first electric shock. The diffusion of external

  7. Sudden Cardiac Arrest

    Science.gov (United States)

    ... Heart Risk Factors & Prevention Heart Diseases & Disorders Atrial Fibrillation (AFib) Sudden Cardiac Arrest (SCA) SCA: Who's At Risk? Prevention of SCA What Causes SCA? SCA Awareness Atrial Flutter Heart Block Heart Failure Sick Sinus Syndrome Substances & Heart Rhythm Disorders Symptoms & ...

  8. Pittsburgh Police Arrest Data

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Arrest data contains information on people taken into custody by City of Pittsburgh police officers. More serious crimes such as felony offenses are more likely to...

  9. Cardiac arrest - cardiopulmonary resuscitation

    Institute of Scientific and Technical Information of China (English)

    Basri Lenjani; Besnik Elshani; Nehat Baftiu; Kelmend Pallaska; Kadir Hyseni; Njazi Gashi; Nexhbedin Karemani; Ilaz Bunjaku; Taxhidin Zaimi; Arianit Jakupi

    2014-01-01

    Objective:To investigate application of cardiopulmonary resuscitation(CPR) measures within the golden minutes inEurope.Methods:The material was taken from theUniversityClinical Center ofKosovo -EmergencyCentre inPristina, during the two(2) year period(2010-2011).The collected date belong to the patients with cardiac arrest have been recorded in the patients' log book protocol at the emergency clinic.Results:During the2010 to2011 in the emergency center of theCUCK inPristina have been treated a total of269 patients with cardiac arrest, of whom159 or59.1% have been treated in2010, and110 patients or40.9% in2011.Of the269 patients treated in the emergency centre,93 or34.6% have exited lethally in the emergency centre, and176 or 65.4% have been transferred to other clinics.In the total number of patients with cardiac arrest, males have dominated with186 cases, or69.1%.The average age of patients included in the survey was56.7 year oldSD±16.0 years.Of the269 patients with cardiac arrest, defibrillation has been applied for93 or34.6% of patients.In the outpatient settings defibrillation has been applied for3 or3.2% of patients.Patients were defibrillated with application of one to four shocks. Of27 cases with who have survived cardiac arrest, none of them have suffered cardiac arrest at home,3 or11.1% of them have suffered cardiac arrest on the street, and24 or88.9% of them have suffered cardiac arrest in the hospital.5 out of27 patients survived have ended with neurological impairment.Cardiac arrest cases were present during all days of the week, but frequently most reported cases have been onMonday with32.0% of cases, and onFriday with24.5% of cases. Conclusions:All survivors from cardiac arrest have received appropriate medical assistance within10 min from attack, which implies that if cardiac arrest occurs near an institution health care(with an opportunity to provide the emergent health care) the rate of survival is higher.

  10. Bed bug aggregation pheromone finally identified.

    Science.gov (United States)

    Gries, Regine; Britton, Robert; Holmes, Michael; Zhai, Huimin; Draper, Jason; Gries, Gerhard

    2015-01-19

    Bed bugs have become a global epidemic and current detection tools are poorly suited for routine surveillance. Despite intense research on bed bug aggregation behavior and the aggregation pheromone, which could be used as a chemical lure, the complete composition of this pheromone has thus far proven elusive. Here, we report that the bed bug aggregation pheromone comprises five volatile components (dimethyl disulfide, dimethyl trisulfide, (E)-2-hexenal, (E)-2-octenal, 2-hexanone), which attract bed bugs to safe shelters, and one less-volatile component (histamine), which causes their arrestment upon contact. In infested premises, a blend of all six components is highly effective at luring bed bugs into traps. The trapping of juvenile and adult bed bugs, with or without recent blood meals, provides strong evidence that this unique pheromone bait could become an effective and inexpensive tool for bed bug detection and potentially their control. PMID:25529634

  11. Cardiac arrest – cardiopulmonary resuscitation

    Directory of Open Access Journals (Sweden)

    Basri Lenjani

    2014-01-01

    Conclusions: All survivors from cardiac arrest have received appropriate medical assistance within 10 min from attack, which implies that if cardiac arrest occurs near an institution health care (with an opportunity to provide the emergent health care the rate of survival is higher.

  12. Metoclopramide-induced cardiac arrest

    Directory of Open Access Journals (Sweden)

    Martha M. Rumore

    2011-11-01

    Full Text Available The authors report a case of cardiac arrest in a patient receiving intravenous (IV metoclopramide and review the pertinent literature. A 62-year-old morbidly obese female admitted for a gastric sleeve procedure, developed cardiac arrest within one minute of receiving metoclopramide 10 mg via slow intravenous (IV injection. Bradycardia at 4 beats/min immediately appeared, progressing rapidly to asystole. Chest compressions restored vital function. Electrocardiogram (ECG revealed ST depression indicative of myocardial injury. Following intubation, the patient was transferred to the intensive care unit. Various cardiac dysrrhythmias including supraventricular tachycardia (SVT associated with hypertension and atrial fibrillation occurred. Following IV esmolol and metoprolol, the patient reverted to normal sinus rhythm. Repeat ECGs revealed ST depression resolution without pre-admission changes. Metoclopramide is a non-specific dopamine receptor antagonist. Seven cases of cardiac arrest and one of sinus arrest with metoclopramide were found in the literature. The metoclopramide prescribing information does not list precautions or adverse drug reactions (ADRs related to cardiac arrest. The reaction is not dose related but may relate to the IV administration route. Coronary artery disease was the sole risk factor identified. According to Naranjo, the association was possible. Other reports of cardiac arrest, severe bradycardia, and SVT were reviewed. In one case, five separate IV doses of 10 mg metoclopramide were immediately followed by asystole repeatedly. The mechanism(s underlying metoclopramide’s cardiac arrest-inducing effects is unknown. Structural similarities to procainamide may play a role. In view of eight previous cases of cardiac arrest from metoclopramide having been reported, further elucidation of this ADR and patient monitoring is needed. Our report should alert clinicians to monitor patients and remain diligent in surveillance and

  13. Sudden Cardiac Arrest (SCA) Risk Assessment

    Science.gov (United States)

    ... Find a Specialist Share Twitter Facebook SCA Risk Assessment Sudden Cardiac Arrest (SCA) occurs abruptly and without ... of all ages and health conditions. Start Risk Assessment The Sudden Cardiac Arrest (SCA) Risk Assessment Tool ...

  14. 33 CFR 154.822 - Detonation arresters, flame arresters, and flame screens.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Detonation arresters, flame arresters, and flame screens. 154.822 Section 154.822 Navigation and Navigable Waters COAST GUARD... BULK Vapor Control Systems § 154.822 Detonation arresters, flame arresters, and flame screens. (a)...

  15. Cognitive and Functional Consequence of Cardiac Arrest.

    Science.gov (United States)

    Perez, Claudia A; Samudra, Niyatee; Aiyagari, Venkatesh

    2016-08-01

    Cardiac arrest is associated with high morbidity and mortality. Better-quality bystander cardiopulmonary resuscitation training, cardiocerebral resuscitation principles, and intensive post-resuscitation hospital care have improved survival. However, cognitive and functional impairment after cardiac arrest remain areas of concern. Research focus has shifted beyond prognostication in the immediate post-arrest period to identification of mechanisms for long-term brain injury and implementation of promising protocols to reduce neuronal injury. These include therapeutic temperature management (TTM), as well as pharmacologic and psychological interventions which also improve overall neurological function. Comprehensive assessment of cognitive function post-arrest is hampered by heterogeneous measures among studies. However, the domains of attention, long-term memory, spatial memory, and executive function appear to be affected. As more patients survive cardiac arrest for longer periods of time, there needs to be a greater focus on interventions that can enhance cognitive and psychosocial function post-arrest. PMID:27311306

  16. Simulated Cardiopulmonary Arrests in a Hospital Setting.

    Science.gov (United States)

    Mishkin, Barbara H.; And Others

    1982-01-01

    Describes a simulated interdisciplinary role rehearsal for cardiopulmonary arrest to prepare nurses to function effectively. Includes needs analysis, program components, and responses of program participants. (Author)

  17. [Out-of-hospital cardiac arrest].

    Science.gov (United States)

    Virkkunen, Ilkka; Hoppu, Sanna; Kämäräinen, Antti

    2011-01-01

    Cardiac arrest as the first symptom of coronary artery disease is not uncommon. Some of previously healthy people with sudden cardiac arrest may be saved by effective resuscitation and post-resuscitative therapy. The majority of cardiac arrest patients experience the cardiac arrest outside of the hospital, in which case early recognition of lifelessness, commencement of basic life support and entry to professional care without delay are the prerequisites for recovery. After the heart has started beating again, the clinical picture of post-resuscitation syndrome must be recognized and appropriate treatment utilized. PMID:22204143

  18. Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells.

    Science.gov (United States)

    Alon, Ronen; Ley, Klaus

    2008-10-01

    The arrest of rolling leukocytes on various target vascular beds is mediated by specialized leukocyte integrins and their endothelial immunoglobulin superfamily (IgSF) ligands. These integrins are kept in largely inactive states and undergo in situ activation upon leukocyte-endothelial contact by both biochemical and mechanical signals from flow-derived shear forces. In vivo and in vitro studies suggest that leukocyte integrin activation involves conformational alterations through inside-out signaling followed by ligand-induced rearrangements accelerated by external forces. This activation process takes place within fractions of seconds by in situ signals transduced to the rolling leukocyte as it encounters specialized endothelial-displayed chemoattractants, collectively termed arrest chemokines. In neutrophils, selectin rolling engagements trigger intermediate affinity integrins to support reversible adhesions before chemokine-triggered arrest. Different leukocyte subsets appear to use different modalities of integrin activation during rolling and arrest at distinct endothelial sites.

  19. The course of circulatory and cerebral recovery after circulatory arrest: influence of pre-arrest, arrest and post-arrest factors.

    Science.gov (United States)

    Jørgensen, E O; Holm, S

    1999-11-01

    We evaluated the influence of pre-arrest, arrest and post-arrest factors on circulatory and neurological recovery for up to 1 year following circulatory arrest of cardio-pulmonary aetiology in 231 patients. Initially, all patients were unconscious and 106 had some cortical activity recorded in the immediate post-resuscitation EEG (Group I), while 125 had no such activity initially (Group II). The following variables were explored: age, sex, medical history, cause and location of arrest, initial cardiac dysrhythmia, duration of life support, metabolic acidosis, pulse-pressure product and heart pump function capacity early after resuscitation. Outcome measures were duration and quality of circulatory survival, cause of death, neurological recovery and ultimate outcome. First year survival was 33% in Group I and 16% in Group II. Severe heart failure and brain death occurred mainly in Group II. Circulatory recovery was negatively influenced by out-of-hospital arrest, metabolic acidosis and pulse-pressure products below 150. Neurological recovery was negatively influenced by initial dysrhythmias other than ventricular fibrillation, pulse-pressure products below 150, post-arrest heart failure and/or pulmonary complications. It seems that circulatory and cerebral outcomes are mainly determined by the global ischaemic insults sustained during the circulatory arrest period. PMID:10625157

  20. In-hospital Cardiac Arrest at Cork University Hospital.

    Science.gov (United States)

    O'Sullivan, E; Deasy, C

    2016-01-01

    We describe the incidence and outcomes of in-hospital cardiac arrest (IHCA) at Cork University Hospital over a one year time period (2011), prior to the implementation of national early warning scoring (NEWS) systems. There were 43 217 coded CUH admissions, in 2011, to 518 in-patient beds. The Hospital In-Patient Enquiry Database was used to identify adults (>/= 18 years) who sustained IHCA. Available Utstein variables were collected. Fifty-two patients were found to be incorrectly coded IHCA. 17 of 63 (27.0%) IHCA survived to discharge. IHCA with shockable rhythm had significantly higher survival. IHCA survival was significantly lower on wards versus any other hospital location. Median days of stay prior to arrest were significantly different between survivors and non-survivors. All survivors (n = 17) had intact neurological outcome post-event. Our outcomes from IHCA are poorest on hospital wards when compared to other areas of the hospital. Those that survive have excellent function and one-year survival.

  1. Chromosomal Aneuploidies and Early Embryonic Developmental Arrest

    Directory of Open Access Journals (Sweden)

    Maria Maurer

    2015-07-01

    Full Text Available Background: Selecting the best embryo for transfer, with the highest chance of achieving a vital pregnancy, is a major goal in current in vitro fertilization (IVF technology. The high rate of embryonic developmental arrest during IVF treatment is one of the limitations in achieving this goal. Chromosomal abnormalities are possibly linked with chromosomal arrest and selection against abnormal fertilization products. The objective of this study was to evaluate the frequency and type of chromosomal abnormalities in preimplantation embryos with developmental arrest. Materials and Methods: This cohort study included blastomeres of embryos with early developmental arrest that were biopsied and analyzed by fluorescence in-situ hybridization (FISH with probes for chromosomes 13, 16, 18, 21 and 22. Forty-five couples undergoing IVF treatment were included, and 119 arrested embryos were biopsied. All probes were obtained from the Kinderwunsch Zentrum, Linz, Austria, between August 2009 and August 2011. Results: Of these embryos, 31.6% were normal for all chromosomes tested, and 68.4% were abnormal. Eleven embryos were uniformly aneuploid, 20 were polyploid, 3 were haploid, 11 displayed mosaicism and 22 embryos exhibited chaotic chromosomal complement. Conclusion: Nearly 70% of arrested embryos exhibit chromosomal errors, making chromosomal abnormalities a major cause of embryonic arrest and may be a further explanation for the high developmental failure rates during culture of the embryos in the IVF setting.

  2. Composite Pressure Vessel Including Crack Arresting Barrier

    Science.gov (United States)

    DeLay, Thomas K. (Inventor)

    2013-01-01

    A pressure vessel includes a ported fitting having an annular flange formed on an end thereof and a tank that envelopes the annular flange. A crack arresting barrier is bonded to and forming a lining of the tank within the outer surface thereof. The crack arresting barrier includes a cured resin having a post-curing ductility rating of at least approximately 60% through the cured resin, and further includes randomly-oriented fibers positioned in and throughout the cured resin.

  3. Sonic Hedgehog Opposes Epithelial Cell Cycle Arrest

    OpenAIRE

    Fan, Hongran; Khavari, Paul A

    1999-01-01

    Stratified epithelium displays an equilibrium between proliferation and cell cycle arrest, a balance that is disrupted in basal cell carcinoma (BCC). Sonic hedgehog (Shh) pathway activation appears sufficient to induce BCC, however, the way it does so is unknown. Shh-induced epidermal hyperplasia is accompanied by continued cell proliferation in normally growth arrested suprabasal cells in vivo. Shh-expressing cells fail to exit S and G2/M phases in response to calcium-induced differentiation...

  4. Paclitaxel Arrests Growth of Intracellular Toxoplasma gondii

    OpenAIRE

    Estes, Randee; Vogel, Nicolas; Mack, Douglas; McLeod, Rima

    1998-01-01

    Addition of paclitaxel (Taxol) at a concentration of 1 μM to Toxoplasma gondii-infected human foreskin fibroblasts arrested parasite multiplication. Division of the T. gondii tachyzoite nucleus was inhibited, leading to syncytium-like parasite structures within the fibroblasts by 24 h after infection and treatment of the cultures. By 4 days after infection and treatment of the cultures with paclitaxel, this inhibition was irreversible, since the arrested intracellular form was incapable of le...

  5. Surface Electrocardiogram Predictors of Sudden Cardiac Arrest

    Science.gov (United States)

    Abdelghani, Samy A.; Rosenthal, Todd M.; Morin, Daniel P.

    2016-01-01

    Background: Heart disease is a major cause of death in industrialized nations, with approximately 50% of these deaths attributable to sudden cardiac arrest. If patients at high risk for sudden cardiac arrest can be identified, their odds of surviving fatal arrhythmias can be significantly improved through prophylactic implantable cardioverter defibrillator placement. This review summarizes the current knowledge pertaining to surface electrocardiogram (ECG) predictors of sudden cardiac arrest. Methods: We conducted a literature review focused on methods of predicting sudden cardiac arrest through noninvasive electrocardiographic testing. Results: Several electrocardiographic-based methods of risk stratification of sudden cardiac arrest have been studied, including QT prolongation, QRS duration, fragmented QRS complexes, early repolarization, Holter monitoring, heart rate variability, heart rate turbulence, signal-averaged ECG, T wave alternans, and T-peak to T-end. These ECG findings have shown variable effectiveness as screening tools. Conclusion: At this time, no individual ECG finding has been found to be able to adequately stratify patients with regard to risk for sudden cardiac arrest. However, one or more of these candidate surface ECG parameters may become useful components of future multifactorial risk stratification calculators. PMID:27660578

  6. Top Ten Bed Bug Tips

    Science.gov (United States)

    ... have bed bugs, not fleas, ticks or other insects. You can compare your insect to the pictures on our Identifying bed bugs ... bedbugs Bed Bugs Home Learn about Bed Bugs — Characteristics of Bed Bugs — Finding Bed Bugs Protecting Your ...

  7. Sex Disparities in Arrest Outcomes for Domestic Violence

    Science.gov (United States)

    Hamilton, Melissa; Worthen, Meredith G. F.

    2011-01-01

    Domestic violence arrests have been historically focused on protecting women and children from abusive men. Arrest patterns continue to reflect this bias with more men arrested for domestic violence compared to women. Such potential gender variations in arrest patterns pave the way to the investigation of disparities by sex of the offender in…

  8. Bed In Summer

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In winter I get up at night And dress by yellow candle-light. In summer, quite the other way, I have to go to bed by day. I have to go to bed and see The birds still hopping on the tree, Or hear the grown-up people' s feet Still going past me in the stree

  9. Fluidized bed incinerator development

    International Nuclear Information System (INIS)

    A fluidized bed incinerator is being developed for burning rad contaminated solid and liquid waste materials. In situ neutralization of acid gases by the bed material, catalytic afterburning, and gas filtration are used to produce a clean flue gas without the use of aqueous scrubbing

  10. Fluidized bed calciner apparatus

    Science.gov (United States)

    Owen, Thomas J.; Klem, Jr., Michael J.; Cash, Robert J.

    1988-01-01

    An apparatus for remotely calcining a slurry or solution feed stream of toxic or hazardous material, such as ammonium diurante slurry or uranyl nitrate solution, is disclosed. The calcining apparatus includes a vertical substantially cylindrical inner shell disposed in a vertical substantially cylindrical outer shell, in which inner shell is disposed a fluidized bed comprising the feed stream material to be calcined and spherical beads to aid in heat transfer. Extending through the outer and inner shells is a feed nozzle for delivering feed material or a cleaning chemical to the beads. Disposed in and extending across the lower portion of the inner shell and upstream of the fluidized bed is a support member for supporting the fluidized bed, the support member having uniform slots for directing uniform gas flow to the fluidized bed from a fluidizing gas orifice disposed upstream of the support member. Disposed in the lower portion of the inner shell are a plurality of internal electric resistance heaters for heating the fluidized bed. Disposed circumferentially about the outside length of the inner shell are a plurality of external heaters for heating the inner shell thereby heating the fluidized bed. Further, connected to the internal and external heaters is a means for maintaining the fluidized bed temperature to within plus or minus approximately 25.degree. C. of a predetermined bed temperature. Disposed about the external heaters is the outer shell for providing radiative heat reflection back to the inner shell.

  11. Bathing a patient in bed

    Science.gov (United States)

    Bed bath; Sponge bath ... Some patients cannot safely leave their beds to bathe. For these people, daily bed baths can help keep their skin healthy, control odor, and increase comfort. If moving the ...

  12. The Organizational Determinants of Police Arrest Decisions

    Science.gov (United States)

    Chappell, Allison T.; MacDonald, John M.; Manz, Patrick W.

    2006-01-01

    A limited amount of research has examined the relationship between characteristics of police organizations and policing styles. In particular, few studies have examined the link between organizational structures and police officer arrest decisions. Wilson's (1968) pioneering case study of police organizations suggested that individual police…

  13. Predictors for outcome among cardiac arrest patients

    DEFF Research Database (Denmark)

    Wibrandt-Johansen, Ida Maria; Norsted, Kristine; Schmidt, Henrik;

    2015-01-01

    BackgroundIn the past decade, early treatment of cardiac arrest (CA) victims has been improved in several ways, leading to more optimistic over all prognoses. However, the global survival rate after out-of-hospital CA (OHCA) is still not more than 5-10%. With a better knowledge of the predictors...

  14. Growth arrest specific protein (GAS) 6

    DEFF Research Database (Denmark)

    Haase, T N; Rasmussen, Morten; Jaksch, C A M;

    2013-01-01

    using RNA microarray and quantitative PCR. The role of a differentially expressed gene, growth arrest specific protein 6 (GAS6), was evaluated in vitro using neonatal rat islets. Results The mRNA level of Gas6, known to be mitogenic in other tissues, was reduced in LP offspring. The mRNA content of Mafa...

  15. Juvenile Arrests, 2007. Juvenile Justice Bulletin

    Science.gov (United States)

    Puzzanchera, Charles

    2009-01-01

    This Bulletin summarizes 2007 juvenile crime and arrest data reported by local law enforcement agencies across the country and cited in the FBI report, "Crime in the United States 2007." The Bulletin describes the extent and nature of juvenile crime that comes to the attention of the justice system. It serves as a baseline for comparison for…

  16. Maternal Cardiac Arrest: A Practical and Comprehensive Review

    Directory of Open Access Journals (Sweden)

    Farida M. Jeejeebhoy

    2013-01-01

    Full Text Available Cardiac arrest during pregnancy is a dedicated chapter in the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care; however, a robust maternal cardiac arrest knowledge translation strategy and emergency response plan is not usually the focus of institutional emergency preparedness programs. Although maternal cardiac arrest is rare, the emergency department is a high-risk area for receiving pregnant women in either prearrest or full cardiac arrest. It is imperative that institutions review and update emergency response plans for a maternal arrest. This review highlights the most recent science, guidelines, and recommended implementation strategies related to a maternal arrest. The aim of this paper is to increase the understanding of the important physiological differences of, and management strategies for, a maternal cardiac arrest, as well as provide institutions with the most up-to-date literature on which they can build emergency preparedness programs for a maternal arrest.

  17. Tapered bed bioreactor

    Science.gov (United States)

    Scott, Charles D.; Hancher, Charles W.

    1977-01-01

    A vertically oriented conically shaped column is used as a fluidized bed bioreactor wherein biologically catalyzed reactions are conducted in a continuous manner. The column utilizes a packing material a support having attached thereto a biologically active catalytic material.

  18. Particle fuel bed tests

    International Nuclear Information System (INIS)

    Gas-cooled reactors, using packed beds of small diameter coated fuel particles have been proposed for compact, high-power systems. The particulate fuel used in the tests was 800 microns in diameter, consisting of a thoria kernel coated with 200 microns of pyrocarbon. Typically, the bed of fuel particles was contained in a ceramic cylinder with porous metallic frits at each end. A dc voltage was applied to the metallic frits and the resulting electric current heated the bed. Heat was removed by passing coolant (helium or hydrogen) through the bed. Candidate frit materials, rhenium, nickel, zirconium carbide, and zirconium oxide were unaffected, while tungsten and tungsten-rhenium lost weight and strength. Zirconium-carbide particles were tested at 2000 K in H2 for 12 hours with no visible reaction or weight loss

  19. Enuresis (Bed-Wetting)

    Science.gov (United States)

    ... get out of bed to go to the bathroom. When do most children achieve bladder control? Children ... ask questions about your child's daytime and nighttime bathroom habits. Then your doctor will do a physical ...

  20. Bed rest and immunity

    Science.gov (United States)

    Sonnenfeld, Gerald; Aviles, Hernan; Butel, Janet S.; Shearer, William T.; Niesel, David; Pandya, Utpal; Allen, Christopher; Ochs, Hans D.; Blancher, Antoine; Abbal, Michel

    2007-02-01

    Space flight has been shown to result in altered immune responses. The current study was designed to investigate this possibility by using the bed rest model of some space flight conditions. A large number of women are included as subjects in the study. The hypothesis being tested is: 60 days head-down tilt bed rest of humans will affect the immune system and resistance to infection. Blood, urine and saliva samples will be obtained from bed rest subjects prior to, at intervals during, and after completion of 60 days of head-down tilt bed rest. Leukocyte blastogenesis, cytokine production and virus reactivation will be assessed. The ability of the subjects to respond appropriately to immunization with the neoantigen bacteriophage φX-174 will also be determined. Bed rest is being carried out at MEDES, Toulouse France, and the University of Texas Medical Branch, Galveston, TX. The studies to be carried out in France will also allow assessment of the effects of muscle/bone exercise and nutritional countermeasures on the immune system in addition to the effects of bed rest.

  1. Dental Calculus Arrest of Dental Caries

    Science.gov (United States)

    Keyes, Paul H.; Rams, Thomas E.

    2016-01-01

    Background An inverse relationship between dental calculus mineralization and dental caries demineralization on teeth has been noted in some studies. Dental calculus may even form superficial layers over existing dental caries and arrest their progression, but this phenomenon has been only rarely documented and infrequently considered in the field of Cariology. To further assess the occurrence of dental calculus arrest of dental caries, this study evaluated a large number of extracted human teeth for the presence and location of dental caries, dental calculus, and dental plaque biofilms. Materials and methods A total of 1,200 teeth were preserved in 10% buffered formal saline, and viewed while moist by a single experienced examiner using a research stereomicroscope at 15-25× magnification. Representative teeth were sectioned and photographed, and their dental plaque biofilms subjected to gram-stain examination with light microscopy at 100× magnification. Results Dental calculus was observed on 1,140 (95%) of the extracted human teeth, and no dental carious lesions were found underlying dental calculus-covered surfaces on 1,139 of these teeth. However, dental calculus arrest of dental caries was found on one (0.54%) of 187 evaluated teeth that presented with unrestored proximal enamel caries. On the distal surface of a maxillary premolar tooth, dental calculus mineralization filled the outer surface cavitation of an incipient dental caries lesion. The dental calculus-covered carious lesion extended only slightly into enamel, and exhibited a brown pigmentation characteristic of inactive or arrested dental caries. In contrast, the tooth's mesial surface, without a superficial layer of dental calculus, had a large carious lesion going through enamel and deep into dentin. Conclusions These observations further document the potential protective effects of dental calculus mineralization against dental caries. PMID:27446993

  2. Nuclear reactor melt arrest and coolability device

    Energy Technology Data Exchange (ETDEWEB)

    Theofanous, Theo G.; Dinh, Nam Truc; Wachowiak, Richard M.

    2016-06-14

    Example embodiments provide a Basemat-Internal Melt Arrest and Coolability device (BiMAC) that offers improved spatial and mechanical characteristics for use in damage prevention and risk mitigation in accident scenarios. Example embodiments may include a BiMAC having an inclination of less than 10-degrees from the basemat floor and/or coolant channels of less than 4 inches in diameter, while maintaining minimum safety margins required by the Nuclear Regulatory Commission.

  3. Aerodynamically generated noise by lightning arrester

    Directory of Open Access Journals (Sweden)

    Váchová J.

    2007-10-01

    Full Text Available This paper presents the general solution of aerodynamically generated noise by lightning arrester. Governing equations are presented in form of Lighthill acoustic analogy, as embodied in the Ffowcs Williams-Hawkings (FW-H equation. This equation is based on conservation laws of fluid mechanics rather than on the wave equation. Thus, the FW-H equation is valid even if the integration surface is in nonlinear region. That’s why the FWH method is superior in aeroacoustics. The FW-H method is implemented in program Fluent and the numerical solution is acquired by Fluent code.The general solution of acoustic signal generated by lightning arrester is shown and the results in form of acoustic pressure and frequency spectrum are presented. The verification of accuracy was made by evaluation of Strouhal number. A comparison of Strouhal number for circumfluence of a cylinder and the lightning arrester was done, because the experimental data for cylinder case are known and these solids are supposed to be respectively in shape relation.

  4. Arrest scenarios in concentrated protein solutions - from hard sphere glasses to arrested spinodal decomposition

    Science.gov (United States)

    Stradner, Anna; Bucciarelli, Saskia; Casal, Lucia; Foffi, Giuseppe; Thurston, George; Farago, Bela; Schurtenberger, Peter

    2014-03-01

    The occurrence of an arrest transition in concentrated colloid suspensions and its dependence on the interaction potential is a hot topic in soft matter. Such arrest transitions can also occur in concentrated protein solutions, as they exist e.g. in biological cells or are increasingly used in pharmaceutical formulations. Here we demonstrate the applicability of concepts from colloid science to understand the dynamics of concentrated protein solutions. In this presentation we report a combination of 3D light scattering, small-angle X-ray scattering and neutron spin echo measurements to study the structural properties as well as the collective and self diffusion of proteins in highly concentrated solutions on the relevant length and time scales. We demonstrate that various arrest scenarios indeed exist for different globular proteins. The proteins chosen are different bovine lens crystallins. We report examples of hard and attractive glass transitions and arrested spinodal decomposition directly linked to the effective pair potentials determined in static scattering experiments for the different proteins. We discuss these different arrest scenarios in view of possible applications of dense protein solutions as well as in view of their possible relevance for living systems.

  5. Hypothermia improves outcome from cardiac arrest.

    Science.gov (United States)

    Bernard, S A

    2005-12-01

    Out-of-hospital cardiac arrest is common and patients who are initially resuscitated by ambulance officers and transported to hospital are usually admitted to the intensive care unit (ICU). In the past, the treatment in the ICU consisted of supportive care only, and most patients remained unconscious due to the severe anoxic neurological injury. It was this neurological injury rather than cardiac complications that caused the high rate of morbidity and mortality. However, in the early 1990's, a series of animal experiments demonstrated convincingly that mild hypothermia induced after return of spontaneous circulation and maintained for several hours dramatically reduced the severity of the anoxic neurological injury. In the mid-1990's, preliminary human studies suggested that mild hypothermia could be induced and maintained in post-cardiac arrest patients without an increase in the rate of cardiac or other complications. In the late 1990's, two prospective, randomised, controlled trials were conducted and the results confirmed the animal data that mild hypothermia induced after resuscitation and maintained for 12 - 24 hours dramatically improved neurological and overall outcomes. On the basis of these studies, mild hypothermia was endorsed in 2003 by the International Liaison Committee on Resuscitation as a recommended treatment for comatose patients with an initial cardiac rhythm of ventricular fibrillation. However, the application of this therapy into routine clinical critical care practice has been slow. The reasons for this are uncertain, but may relate to the relative complexity of the treatment, unfamiliarity with the pathophysiology of hypothermia, lack of clear protocols and/or uncertainty of benefit in particular patients. Therefore, recent research in this area has focused on the development of feasible, inexpensive techniques for the early, rapid induction of mild hypothermia after cardiac arrest. Currently, the most promising strategy is a rapid

  6. Bed bug deterrence

    Directory of Open Access Journals (Sweden)

    Haynes Kenneth F

    2010-09-01

    Full Text Available Abstract A recent study in BMC Biology has determined that the immature stage of the bed bug (the nymph signals its reproductive status to adult males using pheromones and thus avoids the trauma associated with copulation in this species. The success of this nymphal strategy of deterrence is instructive. Against the background of increasing problems with bed bugs, this research raises the question whether pheromones might be used to control them. See research article http://www.biomedcentral.com/1741-7007/8/121

  7. in Spouted Bed

    Directory of Open Access Journals (Sweden)

    Bronislaw Buczek

    2013-01-01

    Full Text Available Samples of active coke, fresh and spent after cleaning flue gases from communal waste incinerators, were investigated. The outer layers of both coke particles were separately removed by comminution in a spouted bed. The samples of both active cokes were analysed by means of densities, mercury porosimetry, and adsorption technique. Remaining cores were examined to determine the degree of consumption of coke by the sorption of hazardous emissions (SO2, HCl, and heavy metals through its bed. Differences in contamination levels within the porous structure of the particles were estimated. The study demonstrated the effectiveness of commercial active coke in the cleaning of flue gases.

  8. Global arrest of translation during invertebrate quiescence.

    Science.gov (United States)

    Hofmann, G E; Hand, S C

    1994-08-30

    Comparing the translational capacities of cell-free systems from aerobically developing embryos of the brine shrimp Artemia franciscana vs. quiescent embryos has revealed a global arrest of protein synthesis. Incorporation rates of [3H]leucine by lysates from 4-h anoxic embryos were 8% of those from aerobic (control) embryos, when assayed at the respective pH values measured for each treatment in vivo. Exposure of embryos to 4 h of aerobic acidosis (elevated CO2 in the presence of oxygen) suppressed protein synthesis to 3% of control values. These latter two experimental treatments promote developmental arrest of Artemia embryos and, concomitantly, cause acute declines in intracellular pH. When lysates from each treatment were assayed over a range of physiologically relevant pH values (pH 6.4-8.0), amino acid incorporation rates in lysates from quiescent embryos were consistently lower than values for the aerobic controls. Acute reversal of pH to alkaline values during the 6-min assays was not sufficient to return the incorporation rates of quiescent lysates to control values. Thus, a stable alteration in translational capacity of quiescent lysates is indicated. Addition of exogenous mRNA did not rescue the suppressed protein synthesis in quiescent lysates, which suggests that the acute blockage of amino acid incorporation is apparently not due to limitation in message. Thus, the results support a role for intracellular pH as an initial signaling event in translational control during quiescence yet, at the same time, indicate that a direct proton effect on the translational machinery is not the sole proximal agent for biosynthetic arrest in this primitive crustacean. PMID:8078909

  9. Hydroxylated PBDEs induce developmental arrest in zebrafish

    Energy Technology Data Exchange (ETDEWEB)

    Usenko, Crystal Y., E-mail: Crystal_usenko@baylor.edu; Hopkins, David C.; Trumble, Stephen J., E-mail: Stephen_trumble@baylor.edu; Bruce, Erica D., E-mail: Erica_bruce@baylor.edu

    2012-07-01

    The ubiquitous spread of polybrominated diphenyl ethers (PBDEs) has led to concerns regarding the metabolites of these congeners, in particular hydroxylated PBDEs. There are limited studies regarding the biological interactions of these chemicals, yet there is some concern they may be more toxic than their parent compounds. In this study three hydroxylated PBDEs were assessed for toxicity in embryonic zebrafish: 3-OH-BDE 47, 5-OH-BDE 47, and 6-OH-BDE 47. All three congeners induced developmental arrest in a concentration-dependent manner; however, 6-OH-BDE 47 induced adverse effects at lower concentrations than the other congeners. Furthermore, all three induced cell death; however apoptosis was not observed. In short-term exposures (24–28 hours post fertilization), all hydroxylated PBDEs generated oxidative stress in the region corresponding to the cell death at 5 and 10 ppm. To further investigate the short-term effects that may be responsible for the developmental arrest observed in this study, gene regulation was assessed for embryos exposed to 0.625 ppm 6-OH-BDE 47 from 24 to 28 hpf. Genes involved in stress response, thyroid hormone regulation, and neurodevelopment were significantly upregulated compared to controls; however, genes related to oxidative stress were either unaffected or downregulated. This study suggests that hydroxylated PBDEs disrupt development, and may induce oxidative stress and potentially disrupt the cholinergic system and thyroid hormone homeostasis. -- Highlights: ► OH-PBDEs induce developmental arrest in a concentration-dependent manner. ► Hydroxyl group location influences biological interaction. ► OH-PBDEs induce oxidative stress. ► Thyroid hormone gene regulation was disrupted following exposure. ► To our knowledge, this is the first whole organism study of OH-PBDE toxicity.

  10. Abulia following an episode of cardiac arrest.

    Science.gov (United States)

    Naik, Vismay Dinesh

    2015-01-01

    The word 'abulia' means a lack of will, initiative or drive. The symptoms of abulia include lack of spontaneous action and speech, reduced emotional responsiveness and social interaction, poor attention and easy distractibility. These symptoms are independent of reduced levels of consciousness or cognitive impairment. We describe a case of a socially active 72-year-old female patient who presented with symptoms of abulia which may have occurred due to damage of the frontosubcortical circuits following an episode of cardiac arrest. The patient's symptoms improved dramatically following treatment with bromocriptine. PMID:26135487

  11. Global arrest of translation during invertebrate quiescence.

    OpenAIRE

    Hofmann, G E; Hand, S C

    1994-01-01

    Comparing the translational capacities of cell-free systems from aerobically developing embryos of the brine shrimp Artemia franciscana vs. quiescent embryos has revealed a global arrest of protein synthesis. Incorporation rates of [3H]leucine by lysates from 4-h anoxic embryos were 8% of those from aerobic (control) embryos, when assayed at the respective pH values measured for each treatment in vivo. Exposure of embryos to 4 h of aerobic acidosis (elevated CO2 in the presence of oxygen) sup...

  12. A case of thyroid storm with cardiac arrest

    Directory of Open Access Journals (Sweden)

    Nakashima Y

    2014-05-01

    Full Text Available Yutaka Nakashima,1 Tsuneaki Kenzaka,2 Masanobu Okayama,3 Eiji Kajii31Department for Support of Rural Medicine, Yamaguchi Grand Medical Center, 2Division of General Medicine, Center for Community Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan; 3Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University School of Medicine, Shimotsuke, JapanAbstract: A 23-year-old man became unconscious while jogging. He immediately received basic life support from a bystander and was transported to our hospital. On arrival, his spontaneous circulation had returned from a state of ventricular fibrillation and pulseless electrical activity. Following admission, hyperthyroidism led to a suspicion of thyroid storm, which was then diagnosed as a possible cause of the cardiac arrest. Although hyperthyroidism-induced cardiac arrest including ventricular fibrillation is rare, it should be considered when diagnosing the cause of treatable cardiac arrest.Keywords: hyperthyroidism, ventricular fibrillation, treatable cardiac arrest, cardiac arrest, cardiopulmonary arrest

  13. Maximum spoutable bed height of spout-fluid bed

    Energy Technology Data Exchange (ETDEWEB)

    Wenqi Zhong; Mingyao Zhang; Baosheng Jin [Southeast University, Nanjing (China). Key Laboratory on Clean Coal Power Generation and Combustion Technology of Ministry of Education

    2006-11-15

    Experimental study on the maximum spoutable bed height of a spout-fluid bed (cross-section of 0.3 m x 0.03 m and height of 2 m) packed with Geldart group D particles has been carried out. The effects of particle size, spout nozzle size and fluidizing gas flow rate on the maximum spoutable bed height were studied. Experimental data were compared to some published experiments and predictions. The results show that the maximum spoutable bed height of spout-fluid bed decreases with increasing particle size and spout nozzle size, which appears the same trend to that of spouted beds. The increasing of fluidizing gas flow rate leads to a sharply decrease in the maximum spoutable bed height. The existent correlations of the maximum spoutable bed height in the literature were observed to involve large discrepancies. Additionally, the flow characteristics when bed materials deeper than the maximum spoutable height were summarized. Under this condition, the spout-fluid bed operated without a stable and coherent spout or fountain assembles the characteristics of jetting fluidized bed. Besides, the mechanisms of spout termination were investigated. It was found that slugging in the spout and growth of instabilities would cause the spout termination in spout-fluid bed.

  14. Electrothermal model for complete metal-oxide surge arresters

    Energy Technology Data Exchange (ETDEWEB)

    Costa, E. Guedes da; Naidu, S.R. [UFPB, Dept. of Electrical Engineering, Campina Grande, PB (Brazil); Lima, A. Guedes de [CEFET-PB, Dept. of Mechanical Engineering, Joao Pessoa, PB (Brazil)

    2001-01-01

    A computational, electrothermal model for a complete metal-oxide surge arrester based on the implicit form of the finite-differences method is presented. The model is used to calculate the cooling curve after the application of overvoltages and the temperature variations during standard test. The model has been checked against experiments carried out on a test section and a complete surge arrester and the behaviour of a hypothetical surge arrester during standard tests simulated. (Author)

  15. Getting Rid of Bed Bugs

    Science.gov (United States)

    ... how you select a company. Related Information Collaborative Strategy on Bed Bugs - highlights ways that all levels of government, community, academia and private industry can work together to reduce bed bugs across ...

  16. Geomechanics of bedded salt

    Energy Technology Data Exchange (ETDEWEB)

    Serata, S.; Milnor, S.W.

    1979-06-08

    Creep data from the literature search is reinterpreted by SGI, resulting in a better understanding of the temperature and stress state dependence of the octahedral creep rate and the octahedral shear strength. The concept of a transition strength between the elastic and the plastic states is in agreement with the data. The elastic and rheological properties of salt are described, and a set of constitutive equations is presented. The dependence of material properties on parameters such as temperature is considered. Findings on the permeability of salt are summarized, and the in-situ behavior of openings in bedded salt is described based on extensive engineering experience. A stress measuring system utilizing a finite element computer code is discussed. Geological factors affecting the stability of salt openings are considered, and the Stress Control Technique for designing stable openings in bedded salt formations is explained.

  17. Geomechanics of bedded salt

    International Nuclear Information System (INIS)

    Creep data from the literature search is reinterpreted by SGI, resulting in a better understanding of the temperature and stress state dependence of the octahedral creep rate and the octahedral shear strength. The concept of a transition strength between the elastic and the plastic states is in agreement with the data. The elastic and rheological properties of salt are described, and a set of constitutive equations is presented. The dependence of material properties on parameters such as temperature is considered. Findings on the permeability of salt are summarized, and the in-situ behavior of openings in bedded salt is described based on extensive engineering experience. A stress measuring system utilizing a finite element computer code is discussed. Geological factors affecting the stability of salt openings are considered, and the Stress Control Technique for designing stable openings in bedded salt formations is explained

  18. Resuscitation, prolonged cardiac arrest, and an automated chest compression device

    DEFF Research Database (Denmark)

    Risom, Martin; Jørgensen, Henrik; Rasmussen, Lars S;

    2010-01-01

    The European Resuscitation Council's 2005 guidelines for cardiopulmonary resuscitation (CPR) emphasize the delivery of uninterrupted chest compressions of adequate depth during cardiac arrest.......The European Resuscitation Council's 2005 guidelines for cardiopulmonary resuscitation (CPR) emphasize the delivery of uninterrupted chest compressions of adequate depth during cardiac arrest....

  19. Evolution of the dragonfly head-arresting system

    Science.gov (United States)

    Gorb, S. N.

    1999-01-01

    The arrester or fixation system of the head in adult Odonata is unique among arthropods. This system involves the organs of two body segments: the head and the neck. It consists of a skeleton–muscle apparatus that sets the arrester parts in motion. The parts comprise formations covered with complicated microstructures: fields of microtrichia on the rear surface of the head and post-cervical sclerites of the neck. The arrester immobilizes the head during feeding or when the dragonfly is in tandem flight. Thus, it may serve as an adaptation to save the head from violent mechanical disturbance and to stabilize gaze in a variety of behavioural situations. This study shows the evolutionary trend of the arrester in the order Odonata by using scanning electron microscopy and measurements of arrester structures in 227 species from 26 odonate families. The arrester design occurring in the Epiophlebiidae, Gomphidae, Neopetaliidae, Petaluridae and Chlorogomphinae is suggested to be the basic one. Two convergent pathways of head-arrester evolution among Zygoptera and Anisoptera are proposed. The possible functional significance of the arrester system is discussed.

  20. Out-of-Hospital Cardiac Arrest in Denmark

    DEFF Research Database (Denmark)

    Wissenberg Jørgensen, Mads

    challenges, due to the victim’s physical location, which brings an inherent risk of delay (or altogether absence) of recognition and treatment of cardiac arrest. A low frequency of bystander cardiopulmonary resuscitation and low 30-day survival after out-of-hospital cardiac arrest were identified nearly ten......BACK COVER TEXT Cardiac arrest is an emergency medical condition characterized by the cessation of cardiac mechanical activity; without immediate and decisive treatment, a victim’s chances of survival are minimal. Out-of-hospital cardiac arrest is a particular arrest subgroup that poses additional...... years ago in Denmark. These findings led to several national initiatives to strengthen bystander resuscitation attempts and advance care. Despite these nationwide efforts, it was unknown prior to this project whether these efforts resulted in changes in resuscitation attempts by bystanders and changes...

  1. Sublingual Microcirculation is Impaired in Post-cardiac Arrest Patients

    DEFF Research Database (Denmark)

    G. Omar, Yasser; Massey, Michael; Wiuff Andersen, Lars;

    2013-01-01

    AIM: We hypothesized that microcirculatory dysfunction, similar to that seen in sepsis, occurs in post-cardiac arrest patients and that better microcirculatory flow will be associated with improved outcome. We also assessed the association between microcirculatory dysfunction and inflammatory...... markers in the post-cardiac arrest state. METHODS: We prospectively evaluated the sublingual microcirculation in post-cardiac arrest patients, severe sepsis/septic shock patients, and healthy control patients using Sidestream Darkfield microscopy. Microcirculatory flow was assessed using...... the microcirculation flow index (MFI) at 6 and 24h in the cardiac arrest patients, and within 6h of emergency department admission in the sepsis and control patients. RESULTS: We evaluated 30 post-cardiac arrest patients, 16 severe sepsis/septic shock patients, and 9 healthy control patients. Sublingual...

  2. Witnessed arrest, but not delayed bystander cardiopulmonary resuscitation improves prehospital cardiac arrest survivial

    OpenAIRE

    Vukmir, R

    2004-01-01

    Methods: This prospective, randomised, double blinded clinical intervention trial enrolled 874 prehospital cardiopulmonary arrest patients encountered in a prehospital urban, suburban, and rural regional emergency medical service (EMS) area. This group underwent conventional advanced cardiac life support intervention followed by empiric early administration of sodium bicarbonate (1 mEq/l), monitoring conventional resuscitation parameters. Survival was measured as presence of vital signs on em...

  3. Performance of metal oxide gapless surge arresters for HVDC systems

    Energy Technology Data Exchange (ETDEWEB)

    Diseko, N.L.

    1990-09-01

    An examination of the electrical stresses which may be imposed upon metal oxide surge arresters in a dc converter station is undertaken by means of simulation of the dc system and associated ac systems in the time domain using a digital computer program. Detailed models of a dc link are developed for temporary overvoltage stresses and steep front stresses. The most critical stresses for each type of dc station arrester due to converter faults and converter malfunctions are identified. The energy stresses were generally determined to be dependent on the converter control and protection strategies adopted during the faults. The arrester energy stresses for faults on both the line side and valve side busses of the converter transformer were determined to be sensitive to the instant of fault application and the duration of the fault. The arrester stresses for ac bus faults were analyzed in detail to determine their statistical distribution relative to the point on wave at which the fault occurred in each affected phase, and to the instant of fault clearance in each phase. Generally, the highest stresses occur for sequential fault occurrence in the phases compared with simultaneous faults. The studies indicate that the stresses in the arresters in a dc pile experiencing the worst duty depend on the number of arresters represented. Modelling only one arrester of a series-connected group does not provide correct results when the fault condition imposes duty on more than one of the arresters in the group. The study also indicates that the highest stresses do not necessarily occur in the single arrester connected across the valve with the highest prospective overvoltage. Hence the capability to represent all valve arresters within one pole is necessary when determining the most onerous stresses. 11 refs., 79 figs., 28 tabs.

  4. Bed Rest Muscular Atrophy

    Science.gov (United States)

    Greenleaf, John E.

    2000-01-01

    A major debilitating response from prolonged bed rest (BR) is muscle atrophy, defined as a "decrease in size of a part of tissue after full development has been attained: a wasting away of tissue as from disuse, old age, injury or disease". Part of the complicated mechanism for the dizziness, increased body instability, and exaggerated gait in patients who arise immediately after BR may be a result of not only foot pain, but also of muscular atrophy and associated reduction in lower limb strength. Also, there seems to be a close association between muscle atrophy and bone atrophy. A discussion of many facets of the total BR homeostatic syndrome has been published. The old adage that use determines form which promotes function of bone (Wolff's law) also applies to those people exposed to prolonged BR (without exercise training) in whom muscle atrophy is a consistent finding. An extreme case involved a 16-year-old boy who was ordered to bed by his mother in 1932: after 50 years in bed he had "a lily-white frame with limbs as thin as the legs of a ladder-back chair". These findings emphasize the close relationship between muscle atrophy and bone atrophy. In addition to loss of muscle mass during deconditioning, there is a significant loss of muscle strength and a decrease in protein synthesis. Because the decreases in force (strength) are proportionately greater than those in fiber size or muscle cross-sectional area, other contributory factors must be involved; muscle fiber dehydration may be important.

  5. Coal Bed Methane Primer

    Energy Technology Data Exchange (ETDEWEB)

    Dan Arthur; Bruce Langhus; Jon Seekins

    2005-05-25

    During the second half of the 1990's Coal Bed Methane (CBM) production increased dramatically nationwide to represent a significant new source of income and natural gas for many independent and established producers. Matching these soaring production rates during this period was a heightened public awareness of environmental concerns. These concerns left unexplained and under-addressed have created a significant growth in public involvement generating literally thousands of unfocused project comments for various regional NEPA efforts resulting in the delayed development of public and fee lands. The accelerating interest in CBM development coupled to the growth in public involvement has prompted the conceptualization of this project for the development of a CBM Primer. The Primer is designed to serve as a summary document, which introduces and encapsulates information pertinent to the development of Coal Bed Methane (CBM), including focused discussions of coal deposits, methane as a natural formed gas, split mineral estates, development techniques, operational issues, producing methods, applicable regulatory frameworks, land and resource management, mitigation measures, preparation of project plans, data availability, Indian Trust issues and relevant environmental technologies. An important aspect of gaining access to federal, state, tribal, or fee lands involves education of a broad array of stakeholders, including land and mineral owners, regulators, conservationists, tribal governments, special interest groups, and numerous others that could be impacted by the development of coal bed methane. Perhaps the most crucial aspect of successfully developing CBM resources is stakeholder education. Currently, an inconsistent picture of CBM exists. There is a significant lack of understanding on the parts of nearly all stakeholders, including industry, government, special interest groups, and land owners. It is envisioned the Primer would being used by a variety of

  6. Relationship between Intrauterine Bacterial Infection and Early Embryonic Developmental Arrest

    Institute of Scientific and Technical Information of China (English)

    Shao-Fei Yan; Xin-Yan Liu; Yun-Fei Cheng; Zhi-Yi Li; Jie Ou; Wei Wang; Feng-Qin Li

    2016-01-01

    Background:Early embryonic developmental arrest is the most commonly understudied adverse outcome of pregnancy.The relevance of intrauterine infection to spontaneous embryonic death is rarely studied and remains unclear.This study aimed to investigate the relationship between intrauterine bacterial infection and early embryonic developmental arrest.Methods:Embryonic chorion tissue and uterine swabs for bacterial detection were obtained from 33 patients who underwent artificial abortion (control group) and from 45 patients who displayed early embryonic developmental arrest (trial group).Results:Intrauterine bacterial infection was discovered in both groups.The infection rate was 24.44% (11/45) in the early embryonic developmental arrest group and 9.09% (3/33) in the artificial abortion group.Classification analysis revealed that the highest detection rate for Micrococcus luteus in the early embryonic developmental arrest group was 13.33% (6/45),and none was detected in the artificial abortion group.M.luteus infection was significantly different between the groups (P < 0.05 as shown by Fisher's exact test).In addition,no correlation was found between intrauterine bacterial infection and history of early embryonic developmental arrest.Conclusions:M.luteus infection is related to early embryonic developmental arrest and might be one of its causative factors.

  7. Pollution performance of 110 kV metal oxide arresters

    Energy Technology Data Exchange (ETDEWEB)

    Chrzan, K.; Pohl, Z. [Technical Univ. of Wroclaw (Poland). Dept. of Electrical Engineering; Grzybowski, S. [Mississippi State Univ., MS (United States). Dept. of Electrical and Computer Engineering; Koehler, W. [Univ. of Stuttgart (Germany). Dept. of Electrical Engineering

    1997-04-01

    Pollution test results of single unit 110 kV metal oxide surge arresters with porcelain housing according to the solid layer and salt fog methods are presented. During 6 hours of testing, the internal and external charge and maximum temperature along the varistor column were measured. The formation of single stable dry bands on the housing was often observed, especially during salt fog tests. In such cases, the varistor temperature can reach about 70 C. The simple electrical model of the arrester enabling calculations of voltages and currents as a function of arrester and pollution parameters is shown.

  8. Resuscitation of a Pediatric Drowning in Hypothermic Cardiac Arrest.

    Science.gov (United States)

    Dragann, Brendan N; Melnychuk, Eric M; Wilson, Christopher J; Lambert, Richard L; Maffei, Frank A

    2016-01-01

    The prognosis of pediatric patients who require prolonged resuscitation after ice water drowning and hypothermic cardiac arrest remains guarded. We report a case of successful prolonged resuscitation of a pediatric patient in hypothermic cardiac arrest who showed severe metabolic derangements and went on to make a rapid and full neurologic recovery without the use of extracoproreal rewarming or mechanical cardiac support. Many ground and air medical emergency medical service programs have policies against interfacility transfer of patients in hypothermic cardiac arrest, calling into question the need to revise current protocols. PMID:27021675

  9. Electronic registration of out-of-hospital cardiac arrests

    DEFF Research Database (Denmark)

    Nielsen, Niels Dalsgaard; Dahl, Michael; Gade, John;

    2007-01-01

    Introduction: The reported incidences of out-of-hospital cardiac arrests (OHCA) in western countries vary considerably. According to the latest report from Danish Cardiac Arrest Database (DCAD) the incidence rate in Denmark in 2004 was 51/100,000/year. The report states however that this number...... of cardiac arrest. 83 of those (28 %) received first aid. The first aid was provided by layman (68 %), physicians (11 %), nurses (11 %) and first-aiders (4 %). In 6 % the identity of the first aid provider was unknown. The majority of the patients (n = 177 (58 %)) had asystole upon ambulance arrival. 37 (12...

  10. Evolution of the dragonfly head-arresting system

    OpenAIRE

    Gorb, S. N.

    1999-01-01

    The arrester or fixation system of the head in adult Odonata is unique among arthropods. This system involves the organs of two body segments: the head and the neck. It consists of a skeleton–muscle apparatus that sets the arrester parts in motion. The parts comprise formations covered with complicated microstructures: fields of microtrichia on the rear surface of the head and post-cervical sclerites of the neck. The arrester immobilizes the head during feeding or when the dragonfly is in tan...

  11. Variability of bed drag on cohesive beds under wave action

    Science.gov (United States)

    Safak, Ilgar

    2016-01-01

    Drag force at the bed acting on water flow is a major control on water circulation and sediment transport. Bed drag has been thoroughly studied in sandy waters, but less so in muddy coastal waters. The variation of bed drag on a muddy shelf is investigated here using field observations of currents, waves, and sediment concentration collected during moderate wind and wave events. To estimate bottom shear stress and the bed drag coefficient, an indirect empirical method of logarithmic fitting to current velocity profiles (log-law), a bottom boundary layer model for combined wave-current flow, and a direct method that uses turbulent fluctuations of velocity are used. The overestimation by the log-law is significantly reduced by taking turbulence suppression due to sediment-induced stratification into account. The best agreement between the model and the direct estimates is obtained by using a hydraulic roughness of 10  m in the model. Direct estimate of bed drag on the muddy bed is found to have a decreasing trend with increasing current speed, and is estimated to be around 0.0025 in conditions where wave-induced flow is relatively weak. Bed drag shows an increase (up to fourfold) with increasing wave energy. These findings can be used to test the bed drag parameterizations in hydrodynamic and sediment transport models and the skills of these models in predicting flows in muddy environments.

  12. MRI in the assessment of growth arrest

    Energy Technology Data Exchange (ETDEWEB)

    Lohman, Martina; Kivisaari, Arto; Kivisaari, Leena [Helsinki Univ. Central Hospital (Finland). Dept. of Radiology; Vehmas, Tapio [Finnish Institute of Occupational Health, Helsinki (Finland); Kallio, Pentti; Puntila, Juha [Department of Paediatric Surgery, Hospital for Children and Adolescents, University Central Hospital, Helsinki (Finland)

    2002-01-01

    Objective: To compare MRI with X-ray tomography in the assessment of bone bridges across the growth plate. Materials and methods: The investigation consisted of two parts. (1) Eleven children with 13 epiphyses suspected of physeal growth arrests were examined with conventional X-ray tomography and MRI. The bar was post-traumatic in eight children, postinfectious in two and due to a congenital, operated pes equinovarus in one. Three blinded radiologists separately evaluated the examinations retrospectively. (2) The images of four children with known physeal bars in the ankle were mixed with 36 normal examinations obtained 1-year after trauma and evaluated blindly by three radiologists. Results: In 5 of 13 epiphysis, the bony bridge was considered smaller on MRI than on X-ray tomography, in 7 of 13 it was considered equal, while it was larger only in one. The interobserver agreement (weighted kappa) was 0.8 (very good) for MRI, 0.76 (good) for X-ray tomography and 0.60 (moderate) for radiographs. The four bony bridges were easily detected on MRI. Conclusions: Compared to MRI, the size of bridges was estimated larger by tomography in about half of the patients. (orig.)

  13. LSP Composite Test Bed Design

    Science.gov (United States)

    Day, Arthur C.; Griess, Kenneth H.

    2013-01-01

    This document provides standalone information for the Lightning Strike Protection (LSP) Composite Substrate Test Bed Design. A six-sheet drawing set is reproduced for reference, as is some additional descriptive information on suitable sensors and use of the test bed.

  14. Joints and Mineral Veins in Limestone-Marl Alternations: Arrest and Fracture Frequencies

    Science.gov (United States)

    Philipp, S. L.; Reyer, D.

    2009-05-01

    Layering is a common feature of many rock masses. In particular, many sedimentary rocks are layered because of depositional changes (stratification), and diagenetic processes. Mechanical layering, where the mechanical properties, particularly the Young's moduli (stiffness), change between layers, may coincide with changes in grain size, mineral content or facies. The mechanical layering of the rock is important because layering commonly results in abrupt changes in local stress fields that may lead to fracture arrest. However, if all the beds in a rock mass have essentially the same Young's modulus and their contacts are welded together (sealed or healed) the beds may function mechanically as a single layer. Here we explore how mechanical layers relate to sedimentary layers in limestone-marl alternations. This we do by investigating the effects of sedimentary layering of the host rock, on the emplacement and geometries of extension fractures such as joints and mineral veins. Detailed field studies were carried out at two localities of well-exposed limestone-marl alternations: (1) the Jurassic Blue Lias at the Glamorgan Coast of South Wales, UK, and (2) the Triassic Muschelkalk in the Kraichgau area, Southwest Germany. In both study areas, calcite veins occur almost exclusively in the cores and damage zones of faults, whereas jointing is pervasive. Fracture arrest, common in mechanically layered host rocks, is primarily controlled by local variations in the stress field, mainly due to three factors: discontinuities (fractures and contacts), changes in host rock mechanical properties, and stress barriers, where the local stress field is unfavorable to fracture propagation. These factors are related in that changes in stiffness and stress barriers are common at contacts between different rock types. A fourth mechanism, namely the material toughness (critical strain energy release rate) of the contact in relation to that of the adjacent layers has been much studied in

  15. Emergency Neurological Life Support: Resuscitation Following Cardiac Arrest.

    Science.gov (United States)

    Rittenberger, Jon C; Friess, Stuart; Polderman, Kees H

    2015-12-01

    Cardiac arrest is the most common cause of death in North America. Neurocritical care interventions, including targeted temperature management (TTM), have significantly improved neurological outcomes in patients successfully resuscitated from cardiac arrest. Therefore, resuscitation following cardiac arrest was chosen as an emergency neurological life support protocol. Patients remaining comatose following resuscitation from cardiac arrest should be considered for TTM. This protocol will review induction, maintenance, and re-warming phases of TTM, along with management of TTM side effects. Aggressive shivering suppression is necessary with this treatment to ensure the maintenance of a target temperature. Ancillary testing, including electrocardiography, computed tomography and/or magnetic resonance imaging of the brain, continuous electroencephalography monitoring, and correction of electrolyte, blood gas, and hematocrit changes, are also necessary to optimize outcomes. PMID:26438463

  16. [Effect of phenibut on the respiratory arrest caused by serotonin].

    Science.gov (United States)

    Tarakanov, I A; Tarasova, N N; Belova, E A; Safonov, V A

    2006-01-01

    The role of the GABAergic system in mechanisms of the respiratory arrest caused by serotonin administration was studied in anaesthetized rats. Under normal conditions, the systemic administration of serotonin (20-60 mg/kg, i.v.) resulted in drastic changes of the respiratory pattern, whereby the initial phase of increased respiratory rate was followed by the respiratory arrest. The preliminary injection of phenibut (400 mg/kg, i.p.) abolished or sharply reduced the duration of the respiratory arrest phase induced by serotonin. Bilateral vagotomy following the phenibut injection potentiated the anti-apnoesic effect of phenibut, which was evidence of the additive action of vagotomy and phenibut administration. The mechanism of apnea caused by serotonin administration is suggested to include a central GABAergic element, which is activated by phenibut so as to counteract the respiratory arrest. PMID:16579056

  17. Hybrid simulation of metal oxide surge-arrester thermal behaviour

    Energy Technology Data Exchange (ETDEWEB)

    Huang, L.; Raghuveer, M.R. [Manitoba Univ., Winnipeg, MB (Canada). Dept. of Electrical and Computer Engineering

    1996-01-01

    A finite-difference-based technique for simulating the thermal behaviour of a metal oxide surge arrester (MOSA) was described. The improved hybrid thermal modelling technique was claimed to accurately represent heat-transfer modes. Fin theory was used to represent arrester sheds. The proposed model, which relies on simple measurements at the arrester terminals, yields the temporal variation of temperature in a MOSA in both the axial and radial direction. The thermal behaviour of a MOSA under steady-state and transient conditions can be simulated using such a model under different environmental conditions. The accuracy of the modelling technique was demonstrated experimentally by measurements conducted on an arrester. 15 refs., 7 figs.

  18. The psychosocial outcome of anoxic brain injury following cardiac arrest

    OpenAIRE

    Wilson, Michelle

    2012-01-01

    Aim of the study The psychosocial outcome of anoxic brain injury following cardiac arrest is a relatively under researched, but clinically important area. The aim of the current study was to add to the limited existing literature exploring the psychosocial outcome for cardiac arrest survivors, but specifically explore if there is a greater impact on psychosocial outcome in individuals experiencing anoxic brain injury as a result. Methods A range of self report measures were used to c...

  19. Usage of Lightning Arrester Line to Feed Light Electrical Loads

    Directory of Open Access Journals (Sweden)

    Hani B. Odeh

    2009-01-01

    Full Text Available In remote areas, light loads (tens of kilowatts are scattered and situated in the field of high voltage lines (66KV and above. These loads are very far from the main feeders/sub-stations (33KV-0.380KV. Feeding such loads in the traditional ways like provision of Diesel-Powered Stations, installation of new distribution lines from the Feeding Centers, or building new Sub-Stations are not practical ways from the economical point of view, because it requires huge additional expenses and will increase electrical power losses. These expenses are not worthy for such loads and therefore, it is necessary to search for other methods to supply them. One of these methods is to use the lightning arrester line as capacitive divider to supply the light loads. In this research, the induced voltage of the lightning arrester line was calculated when it is isolated from the earth. We found the capacitance between lightning arrester line versus the phases and lightning arrester. It was also found the selective power out of the lightning arrester line and the required length which is to be isolated from the earth keeping the main function of the lightning arrester line. When economically comparing between supplying the light electrical loads by traditional ways and the method of lightning arrester, it was found the advantage of using lightning arresters to supply such loads. Also, by using the traditional methods, it was noted that there is a power loss in the power transmission lines by a percentage of 1.8%.

  20. Crack arrest saturation model under combined electrical and mechanical loadings

    OpenAIRE

    R.R. Bhargava; A. Setia

    2009-01-01

    Purpose: The investigation aims at proposing a model for cracked piezoelectric strip which is capable to arrest the crack.Design/methodology/approach: Under the combined effect of electrical and mechanical loadings applied at the edges of the strip, the developed saturation zone is produced at each tip of the crack. To arrest further opening of the crack, the rims of the developed saturation zones are subjected to in-plane cohesive, normal uniform constant saturation point electrical displace...

  1. Al-Qaeda arrest casts shadow over the LHC

    CERN Multimedia

    Dacey, James

    2010-01-01

    "Cern remains on course for the imminent switch-on of the Large Hadron Collider (LHC) despite the media frenzy following the recent arrest of a physicist who had been working at the facility. The researcher in question is a 32-year-old man of Algerian descent who is expected to face trail in France - the country in which he was arrested" (0.5 page)

  2. Wall-to-bed heat transfer in circulating fluidized beds

    Energy Technology Data Exchange (ETDEWEB)

    Fox, W.B.; Grewal, N.S.; Moen, D.A. [Univ. of North Dakota, Grand Forks, ND (United States). Mechanical Engineering Dept.

    1999-05-01

    Circulating fluidized beds (CFBs) have become increasingly important in recent years for coal combustion and gas-solid reactions. Here, heat transfer from the wall of a circulating fluidized bed to the fast bed suspension has been investigated for several materials. The range of investigation includes dense and dilute phase fast fluidization and pneumatic transport. The overall heat transfer coefficient was found to be a function mainly of cross-sectional average suspension density. Effects of superficial velocity and solids mass flux were obscured by their interrelationship to the suspension density. Two models from the literature are evaluated using present and published data.

  3. Pulling a patient up in bed

    Science.gov (United States)

    Moving a patient in bed ... You must move or pull someone up in bed the right way to avoid injuring the patient's ... people to safely move a patient up in bed. Friction from rubbing can scrape or tear the ...

  4. Situational ambiguity and gendered patterns of arrest for intimate partner violence.

    Science.gov (United States)

    Durfee, Alesha

    2012-01-01

    Using data from the 2005 National Incident-Based Reporting System (NIBRS), this analysis focuses on the impacts that domestic violence mandatory arrest policies have on arrest outcomes in "situationally ambiguous" cases: cases where both the female and male partners have been identified by police as both a victim and an offender. Results indicate that although officers arrest male partners more frequently than female partners, after controlling for incident and individual factors, mandatory arrest policies disproportionately affect women. Furthermore, correlates of arrest differ for male-only arrests versus female-only arrests. These findings are discussed in the context of changing legal responses to domestic violence. PMID:22411299

  5. Changing the guard: Polymer replaces porcelain for surge arresters

    Energy Technology Data Exchange (ETDEWEB)

    Skytt, T.; Gleimar, H. E. G.

    2002-07-01

    Surge arresters are safety devices which quickly and effectively limit the over voltages that can arise in transmission networks following lightning, switching and other transient events. The earliest forms of overvoltage protection, a simple air gap between electrodes, have long since been replaced by a new generation of gapless arresters with series-connected, non-linear zinc oxide varistors contained in a porcelain housing. Now these porcelain type surge arresters are being replaced by a new type, called PEXLIM (Polymeric EXcellent LIMiter), which uses the same block of zinc oxide as the porcelain type, but its housing is made of silicon rubber, a polymer. The new lightweight insulation material shows a number of properties superior to the porcelain, such as enhanced product safety and ease of handling. It is also more durable, resilient, yet solid and compact, water-repellent, lightweight, resistant to aging or light or ultra-violet radiation, as well as fire, has good electrical properties, and is environmentally friendly since it does not contain any substances harmful to the environment. These properties make this new type of surge arrester highly suitable for use in earthquake-prone areas; it can also replace more expensive and maintenance-intensive equipment. Having successfully broken into the lower voltage systems, these new type of surge arresters are now rapidly gaining ground at the higher voltage levels. ABB, the developer of PEXLIM, has already supplied these arresters to North America for use in an 800-kV grid. As further proof of its growing popularity, last year PEXLIM made up over half of the surge arrester production for applications up to and including 245 kV. 1 tab., 6 figs.

  6. Nursing students’ knowledge about arrest rhythms and their treatment

    Directory of Open Access Journals (Sweden)

    Aikaterini Kyrgianidou

    2014-04-01

    Full Text Available Cardiovascular diseases are one of the leading causes of death worldwide. Knowledge of health professionals for the arrest rhythms, is considered particularly important for the early recognition and proper treatment. Aim: The purpose of the present study was to assess the knowledge of nursing students on arrest rhythms and how to treat them. Material and Methods: The sample studied included 151 students from the Department of Nursing A' (n = 60, 40% and B' (n = 91, 60%, TEI of Athens, of whom 83% (n=125 were women and 17% (n=26 were men with a mean age of 23 years. Data collection was performed with specially designed questionnaire, that apart from demographics and students’ education level, it included ten questions about arrest rhythms’ knowledge and also self-assessment questions of their level of knowledge. The data were analyzed with the SPSS package v.19, using the criteria t-Test and χ2. Results: Of all the participants in the research, 95% (n = 144 did not answer correctly more than 6 questions from a total of 10. The students of the Department of Nursing A’ recognized with greater accuracy the arrest rhythms (p = 0.003. Those studying in lower semester acknowledged best the arrest rhythms (p = 0.002. Students who had recently attended course in basic or advanced resuscitation recognized best the arrest rhythms (p = 0.006. Older students knew better right treatment of the arrest rhythms (p = 0.037. Also, students who had attended the course of cardiac nursing in the last year, knew better the right treatment (p <0.001. Finally, the level of self-assessment was in line with the actual level of knowledge of students (p = 0.05. Conclusions: Continuous attendance of courses, education on certified programs and refresh courses help to maintain a good level of knowledge for longer periods.

  7. The stringent response and cell cycle arrest in Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Daniel J Ferullo

    2008-12-01

    Full Text Available The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli. Wild type cells undergo a RelA-dependent arrest after treatment with serine hydroxamate to contain an integer number of chromosomes and a replication origin-to-terminus ratio of 1. The growth rate prior to starvation determines the number of chromosomes upon arrest. Nucleoids of these cells are decondensed; in the absence of the ability to synthesize ppGpp, nucleoids become highly condensed, similar to that seen after treatment with the translational inhibitor chloramphenicol. After induction of the stringent response, while regions corresponding to the origins of replication segregate, the termini remain colocalized in wild-type cells. In contrast, cells arrested by rifampicin and cephalexin do not show colocalized termini, suggesting that the stringent response arrests chromosome segregation at a specific point. Release from starvation causes rapid nucleoid reorganization, chromosome segregation, and resumption of replication. Arrest of replication and inhibition of colony formation by ppGpp accumulation is relieved in seqA and dam mutants, although other aspects of the stringent response appear to be intact. We propose that DNA methylation and SeqA binding to non-origin loci is necessary to enforce a full stringent arrest, affecting both initiation of replication and chromosome segregation. This is the first indication that bacterial chromosome segregation, whose mechanism is not understood, is a step that may be regulated in response to environmental conditions.

  8. Torsion testing of bed joints

    DEFF Research Database (Denmark)

    Hansen, Klavs Feilberg; Pedersen, Carsten Mørk

    2008-01-01

    This paper describes a simple test method for determining the torsion strength of a single bed joint between two bricks and presents results from testing using this test method. The setup for the torsion test is well defined, require minimal preparation of the test specimen and the test can...... be carried out directly in a normal testing machine. The torsion strength is believed to be the most important parameter in out-of-plane resistance of masonry walls subjected to bending about an axis perpendicular to the bed joints. The paper also contains a few test results from bending of small walls about...... an axis perpendicular to the bed joints, which indicate the close connection between these results and results from torsion tests. These characteristics make the torsion strength well suited to act as substitute parameter for the bending strength of masonry about an axis perpendicular to the bed joints....

  9. Sea bed mapping and inspection

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The conference has 24 presentations on the topics: Sea bed mapping, inspection, positioning, hydrography, marine archaeology, remote operation vehicles and computerized simulation technologies, oil field activities and plans, technological experiences and problems. (tk)

  10. Bed Bugs: The Australian Response

    Directory of Open Access Journals (Sweden)

    Richard C. Russell

    2011-04-01

    Full Text Available Australia has experienced a sudden and unexpected resurgence in bed bug infestations from both Cimex lectularius L. and Cimex hemipterus F. A survey in 2006 revealed that infestations had increased across the nation by an average of 4,500% since the start of the decade. In response, a multi-disciplinary approach to combat the rise of this public health pest was implemented and involved the coordinated efforts of several organizations. The key components of the strategy included the introduction of a pest management standard ‘A Code of Practice for the Control of Bed Bug Infestations in Australia’ that defines and promotes ‘best practice’ in bed bug eradication, the development of a policy and procedural guide for accommodation providers, education of stakeholders in best management practices, and research. These strategies continue to evolve with developments that lead to improvements in ‘best practice’ while bed bugs remain problematic in Australia.

  11. Better backs by better beds?

    DEFF Research Database (Denmark)

    Bergholdt, Kim; Fabricius, Rasmus N; Bendix, Tom

    2008-01-01

    using the probably most relevant "worst case" data. There were no relevant difference between the effects of the water bed and the foam bed. CONCLUSION: The Waterbed and foam mattress' did influence back symptoms, function and sleep more positively as apposed to the hard mattress, but the differences...... mattresses have a positive effect on LBP, and especially a hard mattress is commonly believed to have a positive effect. METHODS: One hundred sixty CLBP patients were randomized to 1 of 3 groups, having a mattress/bed mounted in their sleeping room for 1 month. The beds were: (1) waterbed (Akva), (2) body......-conforming foam mattress (Tempur), and (3) a hard mattress (Innovation Futon). At baseline and after 4 weeks, a blinded observer interviewed the patients on LBP levels (0-10), daily function (activities of daily living, 0-30), and on the amount of sleeping hours/night. RESULTS: Because of dropout of 19 patients...

  12. Visualizing Vpr-induced G2 arrest and apoptosis.

    Directory of Open Access Journals (Sweden)

    Tomoyuki Murakami

    Full Text Available Vpr is an accessory protein of human immunodeficiency virus type 1 (HIV-1 with multiple functions. The induction of G2 arrest by Vpr plays a particularly important role in efficient viral replication because the transcriptional activity of the HIV-1 long terminal repeat is most active in G2 phase. The regulation of apoptosis by Vpr is also important for immune suppression and pathogenesis during HIV infection. However, it is not known whether Vpr-induced apoptosis depends on the ability of Vpr to induce G2 arrest, and the dynamics of Vpr-induced G2 arrest and apoptosis have not been visualized. We performed time-lapse imaging to examine the temporal relationship between Vpr-induced G2 arrest and apoptosis using HeLa cells containing the fluorescent ubiquitination-based cell cycle indicator2 (Fucci2. The dynamics of G2 arrest and subsequent long-term mitotic cell rounding in cells transfected with the Vpr-expression vector were visualized. These cells underwent nuclear mis-segregation after prolonged mitotic processes and then entered G1 phase. Some cells subsequently displayed evidence of apoptosis after prolonged mitotic processes and nuclear mis-segregation. Interestingly, Vpr-induced apoptosis was seldom observed in S or G2 phase. Likewise, visualization of synchronized HeLa/Fucci2 cells infected with an adenoviral vector expressing Vpr clearly showed that Vpr arrests the cell cycle at G2 phase, but does not induce apoptosis at S or G2 phase. Furthermore, time-lapse imaging of HeLa/Fucci2 cells expressing SCAT3.1, a caspase-3-sensitive fusion protein, clearly demonstrated that Vpr induces caspase-3-dependent apoptosis. Finally, to examine whether the effects of Vpr on G2 arrest and apoptosis were reversible, we performed live-cell imaging of a destabilizing domain fusion Vpr, which enabled rapid stabilization and destabilization by Shield1. The effects of Vpr on G2 arrest and subsequent apoptosis were reversible. This study is the first to

  13. Bed-exit alarm effectiveness

    Science.gov (United States)

    Capezuti, Elizabeth; Brush, Barbara L.; Lane, Stephen; Rabinowitz, Hannah U.; Secic, Michelle

    2009-01-01

    This study describes the accuracy of two types of bed-exit alarms to detect bed-exiting body movements: pressure-sensitive and a pressure sensitive combined with infrared beam detectors (dual sensor system). We also evaluated the occurrence of nuisance alarms, or alarms that are activated when a participant does not attempt to get out of bed. Fourteen nursing home residents were directly observed for a total of 256 nights or 1,636.5 hours; an average of 18.3 ± 22.3 (± S.D.) nights/participant for an average of 6.4 ± 1.2 hours/night. After adjusting for body movements via repeated measures, Poisson regression modeling, the least squares adjusted means show a marginally significant difference between the type of alarm groups on the number of true positives (mean/S.E.M. = 0.086/1.617) for pressure-sensitive vs. dual sensor alarm (0.593/1.238; p = 0.0599) indicating that the dual sensor alarm may have a higher number of true positives. While the dual sensor bed-exit alarm was more accurate than the pressure sensitive alarm in identifying bed-exiting body movements and reducing the incidence of false alarms, false alarms were not eliminated altogether. Alarms are not a substitute for staff; adequate staff availability is still necessary when residents need or wish to exit bed. PMID:18508138

  14. Northern European Satellite Test Bed

    Science.gov (United States)

    Schuster-Bruce, Alan; Lawson, James; Quinlan, Michael; McGregor, Andrew

    Satellite Based Augmentation Systems are being developed in Europe (EGNOS), the USA (WAAS), and in Japan (MSAS). As part of their support to EGNOS, NATS and Racal have developed and deployed a prototype SBAS system called the Northern European Satellite Test Bed (NEST Bed). NEST Bed uses GPS L1/L2 reference stations at: Aberdeen, Rotterdam, Ankara, Cadiz, Keflavik, and Bronnoysund. Data is sent to the Master Control Centre at NATS Gatwick Services Management Centre for processing. The resulting 250 bits-per-second message is sent to Goonhilly for up-linking by BT to the Navigation Payload of either the Inmarsat AOR-E or F5 spare satellite. NEST Bed was deployed and commissioned during summer 1998, and flight tests were successfully demonstrated at the September 1998 Farnborough Air Show where approaches were flown to Boscombe Down on the DERA BAC1-11 aircraft. In October 1998, a NATS/FAA flight trial was held in Iceland involving NEST Bed and the FAA NSTB. NEST Bed is also being used for SARPS validation.

  15. Current Pharmacological Advances in the Treatment of Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Andry Papastylianou

    2012-01-01

    Full Text Available Cardiac arrest is defined as the sudden cessation of spontaneous ventilation and circulation. Within 15 seconds of cardiac arrest, the patient loses consciousness, electroencephalogram becomes flat after 30 seconds, pupils dilate fully after 60 seconds, and cerebral damage takes place within 90–300 seconds. It is essential to act immediately as irreversible damage can occur in a short time. Cardiopulmonary resuscitation (CPR is an attempt to restore spontaneous circulation through a broad range of interventions which are early defibrillation, high-quality and uninterrupted chest compressions, advanced airway interventions, and pharmacological interventions. Drugs should be considered only after initial shocks have been delivered (when indicated and chest compressions and ventilation have been started. During cardiopulmonary resuscitation, no specific drug therapy has been shown to improve survival to hospital discharge after cardiac arrest, and only few drugs have a proven benefit for short-term survival. This paper reviews current pharmacological treatment of cardiac arrest. There are three groups of drugs relevant to the management of cardiac arrest: vasopressors, antiarrhythmics, and other drugs such as sodium bicarbonate, calcium, magnesium, atropine, fibrinolytic drugs, and corticosteroids.

  16. Sculpting Pickering Emulsion Droplets by Arrest and Jamming

    Science.gov (United States)

    Burke, Christopher; Wei, Zengyi; Caggioni, Marco; Spicer, Patrick; Atherton, Tim

    Pickering emulsion droplets can be arrested into non-spherical shapes--useful for applications such as active delivery--through a general mechanism of deformation followed by absorption of additional colloidal particles onto the interface, relaxation of the droplet caused by surface tension and arrest at some point due to crowding of the particles. We perform simulations of the arrest process to clarify the relative importance of diffusive rearrangement of particles and collective forcing due to surface evolution. Experiment and theory are compared, giving insight into the stability of the resulting capsules and the robustness of the production process for higher-throughput production in, for example, microfluidic systems. We adapt theoretical tools from the jamming literature to better understand the arrested configurations and long timescale evolution of the system: using linear programming and a penalty function approach, we identify unjamming motions in kinetically arrested states. We propose a paradigm of ``metric jamming'' to describe the limiting behavior of this class of system: a structure is metric-jammed if it is stable with respect to collective motion of the particles as well as evolution of the hypersurface on which the packing is embedded. Supported by a Cottrell Award from the Research Corporation for Science Advancement.

  17. 49 CFR 236.336 - Locking bed.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Locking bed. 236.336 Section 236.336 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Instructions § 236.336 Locking bed. The various parts of the locking bed, locking bed supports, and tappet...

  18. Alphaherpesvirus Subversion of Stress-Induced Translational Arrest

    Directory of Open Access Journals (Sweden)

    Renée L. Finnen

    2016-03-01

    Full Text Available In this article, we provide an overview of translational arrest in eukaryotic cells in response to stress and the tactics used specifically by alphaherpesviruses to overcome translational arrest. One consequence of translational arrest is the formation of cytoplasmic compartments called stress granules (SGs. Many viruses target SGs for disruption and/or modification, including the alphaherpesvirus herpes simplex virus type 2 (HSV-2. Recently, it was discovered that HSV-2 disrupts SG formation early after infection via virion host shutoff protein (vhs, an endoribonuclease that is packaged within the HSV-2 virion. We review this discovery and discuss the insights it has provided into SG biology as well as its potential significance in HSV-2 infection. A model for vhs-mediated disruption of SG formation is presented.

  19. Alphaherpesvirus Subversion of Stress-Induced Translational Arrest

    Science.gov (United States)

    Finnen, Renée L.; Banfield, Bruce W.

    2016-01-01

    In this article, we provide an overview of translational arrest in eukaryotic cells in response to stress and the tactics used specifically by alphaherpesviruses to overcome translational arrest. One consequence of translational arrest is the formation of cytoplasmic compartments called stress granules (SGs). Many viruses target SGs for disruption and/or modification, including the alphaherpesvirus herpes simplex virus type 2 (HSV-2). Recently, it was discovered that HSV-2 disrupts SG formation early after infection via virion host shutoff protein (vhs), an endoribonuclease that is packaged within the HSV-2 virion. We review this discovery and discuss the insights it has provided into SG biology as well as its potential significance in HSV-2 infection. A model for vhs-mediated disruption of SG formation is presented. PMID:26999187

  20. Investigating Different ZnO Arresters Models against Transient Waves

    Directory of Open Access Journals (Sweden)

    A. Babaee

    2011-12-01

    Full Text Available Metal oxide surge arresters have dynamic characteristics that are significant for over voltage coordination studies involving fast front surges. Several models with acceptable accuracy have been proposed to simulate this frequency-dependent behavior. In this paper, various electrical models are presented for surge arrester performance simulation against lightning impulse. The desirable model is obtained by using simulation results of the existing models and experimental tests. The IEEE proposed model is a proportional model can give satisfactory results for discharge currents within a range of time to crest for 0.5 to 45 :s but due to no existing residual voltage resulting switching current on the manufacture's datasheets decrease its performance generally. In this study the maximum residual voltage due to current impulse is analyzed too. In additional, the amount of discharged energy by surge arrester is focused.

  1. Fatigue crack arrest in a self-healing polymer composite

    Energy Technology Data Exchange (ETDEWEB)

    Brown, E. N. (Eric N.); White, S. R. (Scott R.); Sottos, Nancy R.

    2004-01-01

    A comprehensive experimental program is performed to assess the in situ fatigue behavior of a self-healing polymer. A fatigue-life-extension protocol is established for characterizing healing efficiency of the self-healing epoxy under cyclic loading. At moderate {Delta}K{sub I} and at high {Delta}K{sub I}, when a rest period is employed, in situ healing extends fatigue life though temporary crack arrest and retardation. In situ self-healing permanently arrests crack growth at low {delta}K{sub I} and at moderate {Delta}K{sub I}, when a rest period is employed. Fatigue crack retardation and arrest result from two primary crack-tip shielding mechanisms: hydrodynamic pressure in the viscous healing agent and artificial crack closure. Application of self-healing functionality to fatigue slows the crack growth rate and increases the fatigue threshold.

  2. Drug therapy in cardiac arrest: a review of the literature.

    Science.gov (United States)

    Lundin, Andreas; Djärv, Therese; Engdahl, Johan; Hollenberg, Jacob; Nordberg, Per; Ravn-Fischer, Annika; Ringh, Mattias; Rysz, Susanne; Svensson, Leif; Herlitz, Johan; Lundgren, Peter

    2016-01-01

    The aim of this study was to review the literature on human studies of drug therapy in cardiac arrest during the last 25 years. In May 2015, a systematic literature search was performed in PubMed, Embase, the Cochrane Library, and CRD databases. Prospective interventional and observational studies evaluating a specified drug therapy in human cardiac arrest reporting a clinical endpoint [i.e. return of spontaneous circulation (ROSC) or survival] and published in English 1990 or later were included, whereas animal studies, case series and reports, studies of drug administration, drug pharmacology, non-specified drug therapies, preventive drug therapy, drug administration after ROSC, studies with primarily physiological endpoints, and studies of traumatic cardiac arrest were excluded. The literature search identified a total of 8936 articles. Eighty-eight articles met our inclusion criteria and were included in the review. We identified no human study in which drug therapy, compared with placebo, improved long-term survival. Regarding adrenaline and amiodarone, the drugs currently recommended in cardiac arrest, two prospective randomized placebo-controlled trials, were identified for adrenaline, and one for amiodarone, but they were all underpowered to detect differences in survival to hospital discharge. Of all reviewed studies, only one recent prospective study demonstrated improved neurological outcome with one therapy over another using a combination of vasopressin, steroids, and adrenaline as the intervention compared with standard adrenaline administration. The evidence base for drug therapy in cardiac arrest is scarce. However, many human studies on drug therapy in cardiac arrest have not been powered to identify differences in important clinical outcomes such as survival to hospital discharge and favourable neurological outcome. Efforts are needed to initiate large multicentre prospective randomized clinical trials to evaluate both currently recommended and

  3. Increased risk of sudden cardiac arrest in obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Warnier, Miriam Jacoba; Blom, Marieke Tabo; Bardai, Abdennasser;

    2013-01-01

    . METHODS: A community-based case-control study was performed, with 1310 cases of SCA of the ARREST study and 5793 age, sex and SCA-date matched non-SCA controls from the PHARMO database. Only incident SCA cases, age older than 40 years, that resulted from unequivocal cardiac causes......BACKGROUND: We aimed to determine whether (1) patients with obstructive pulmonary disease (OPD) have an increased risk of sudden cardiac arrest (SCA) due to ventricular tachycardia or fibrillation (VT/VF), and (2) the SCA risk is mediated by cardiovascular risk-profile and/or respiratory drug use...

  4. Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

    DEFF Research Database (Denmark)

    Westhall, Erik; Rossetti, Andrea O; van Rootselaar, Anne-Fleur;

    2016-01-01

    OBJECTIVE: To identify reliable predictors of outcome in comatose patients after cardiac arrest using a single routine EEG and standardized interpretation according to the terminology proposed by the American Clinical Neurophysiology Society. METHODS: In this cohort study, 4 EEG specialists...... patients. EEGs were recorded in 103 patients at a median 77 hours after cardiac arrest; 37% had a highly malignant EEG and all had a poor outcome (specificity 100%, sensitivity 50%). Any malignant EEG feature had a low specificity to predict poor prognosis (48%) but if 2 malignant EEG features were present...

  5. Cdc20 control of cell fate during prolonged mitotic arrest

    DEFF Research Database (Denmark)

    Nilsson, Jakob

    2011-01-01

    The fate of cells arrested in mitosis by antimitotic compounds is complex but is influenced by competition between pathways promoting cell death and pathways promoting mitotic exit. As components of both of these pathways are regulated by Cdc20-dependent degradation, I hypothesize that variations...... in Cdc20 protein levels, rather than mutations in checkpoint genes, could affect cell fate during prolonged mitotic arrest. This hypothesis is supported by experiments where manipulation of Cdc20 levels affects the response to antimitotic compounds. The observed differences in Cdc20 levels between cell...

  6. Particle motion in fluidised beds

    International Nuclear Information System (INIS)

    Gas fluidised beds are important components in many process industries, e.g. coal combustors and granulators, but not much is known about the movement of the solids. Positron Emission Particle Tracking (PEPT) enables the movement of a single, radioactive tracer particle to be followed rapidly and faithfully. Experiments were carried out in columns sized between 70 and 240mm. diameter, operating in the bubbling regime at ambient process conditions using particles of group B and D (Geldart Classification). Particle motion was tracked and the data applied to models for particle movement at the gas distributor as well as close to other surfaces and to models for particle circulation in beds of cohesive particles. In the light of these data, models for particle and bubble interaction, particle circulation, segregation, attrition, erosion, heat transfer and fluidised bed scale-up rules were reassessed. Particle motion is directly caused by bubble motion, and their velocities were found to be equal for particles travelling in a bubble. PEPT enables particle circulation to be measured, giving a more accurate correlation for future predictions. Particle motion follows the scale-up rules based on similarities of the bubble motion in the bed. A new group of parameters was identified controlling the amount of attrition in fluidised beds and a new model to predict attrition is proposed. (author)

  7. Designing a CR Test bed

    DEFF Research Database (Denmark)

    Cattoni, Andrea Fabio; Buthler, Jakob Lindbjerg; Tonelli, Oscar;

    2014-01-01

    Research on intelligent and reconfigurable wireless systems is in continuous evolution. Nevertheless, in order to fix some keystones, more and more researchers are entering the idea of research-oriented test beds. Unfortunately, it is very difficult for a wide number of research groups to start...... with their own set up, since the potential costs and efforts could not pay back in term of expected research results. Software Defined Radio solutions offer an easy way to communication researchers for the development of customized research test beds. While several hardware products are commercially available...... they are up and running in generating results. With this chapter we would like to provide a tutorial guide, based on direct experience, on how to enter in the world of test bed-based research, providing both insight on the issues encountered in every day development, and practical solutions. Finally...

  8. 19 CFR 162.63 - Arrests and seizures.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Arrests and seizures. 162.63 Section 162.63 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) INSPECTION, SEARCH, AND SEIZURE Controlled Substances, Narcotics, and Marihuana §...

  9. Anaphylactic shock and cardiac arrest caused by thiamine infusion

    DEFF Research Database (Denmark)

    Juel, Jacob; Pareek, Manan; Langfrits, Christian Sigvald;

    2013-01-01

    intoxication and developed cardiac arrest due to anaphylactic shock following intravenous thiamine infusion. The patient was successfully resuscitated after 15 min and repeated epinephrine administrations. He was discharged in good health after 14 days. This case report emphasises both the importance...

  10. Design of Lightning Arresters for Electrical Power Systems Protection

    Directory of Open Access Journals (Sweden)

    Shehab Abdulwadood

    2013-01-01

    Full Text Available This paper presents an overview of how the lightning strikes and their effects on power distribution systems can be modeled, where the results give a clear picture of how to eliminate the devastating impact, caused by lightning, by using lightning arresters. The program ATP-Draw (Alternative Transient Program was used to simulate the problem and was applied on a part of a power network.The simulation was done once when the lightning strikes a transmission line and a substation with no lightning arresters in use and once more with their use. The source of the lightning was represented by the ATP models (Type-15 surge function and Type-13 ramp function and the surge arrester was represented by the MOV-Type 92 component. The voltage was recorded at the substation 110/22 kV and at all loads in the electric network, and was drawn by the PlotXWin program. The results obtained indicate that the voltages induced by the lightning can reach values of the order of millions over insulation flashover levels for 22 kV equipment, where is clearly seen in Fig. 12 to 16 and Tab.10, which requires the installation of lightning arresters.

  11. Heart Attack or Sudden Cardiac Arrest: How Are They Different?

    Science.gov (United States)

    ... for Heart360 Cardiovascular Conditions • Conditions Home • Arrhythmia and Atrial Fibrillation • Cardiac Arrest • Cardiac Rehab • Cardiomyopathy • Cardiovascular Conditions of Childhood • Cholesterol • Congenital Heart Defects • Diabetes • Heart Attack • Heart Failure (HF) • Heart Valve Problems and Disease • High Blood ...

  12. Ventilation and gas exchange management after cardiac arrest.

    Science.gov (United States)

    Sutherasan, Yuda; Raimondo, Pasquale; Pelosi, Paolo

    2015-12-01

    For several decades, physicians had integrated several interventions aiming to improve the outcomes in post-cardiac arrest patients. However, the mortality rate after cardiac arrest is still as high as 50%. Post-cardiac arrest syndrome is associated with high morbidity and mortality due to not only poor neurological outcome and cardiovascular failure but also respiratory dysfunction. To minimize ventilator-associated lung injury, protective mechanical ventilation by using low tidal volume ventilation and driving pressure may decrease pulmonary complications and improve survival. Low level of positive end-expiratory pressure (PEEP) can be initiated and titrated with careful cardiac output and respiratory mechanics monitoring. Furthermore, optimizing gas exchange by avoiding hypoxia and hyperoxia as well as maintaining normocarbia may improve neurological and survival outcome. Early multidisciplinary cardiac rehabilitation intervention is recommended. Minimally invasive monitoring techniques, that is, echocardiography, transpulmonary thermodilution method measuring extravascular lung water, as well as transcranial Doppler ultrasound, might be useful to improve appropriate management of post-cardiac arrest patients. PMID:26670813

  13. Bad Behavior : Delinquency, Arrest and Early School Leaving

    NARCIS (Netherlands)

    Ward, Shannon; Williams, J.; van Ours, Jan

    2015-01-01

    In this paper we investigate the effects of delinquency and arrest on school leaving using information on males from the National Longitudinal Survey of Youth 1997. We use a multivariate mixed proportional hazard framework in order to account for common unobserved confounders and reverse causality.

  14. Collapse arresting in an inhomogeneous quintic nonlinear Schrodinger model

    DEFF Research Database (Denmark)

    Gaididei, Yuri Borisovich; Schjødt-Eriksen, Jens; Christiansen, Peter Leth

    1999-01-01

    Collapse of (1 + 1)-dimensional beams in the inhomogeneous one-dimensional quintic nonlinear Schrodinger equation is analyzed both numerically and analytically. It is shown that in the vicinity of a narrow attractive inhomogeneity, the collapse of beams in which the homogeneous medium would blow ...... may be delayed and even arrested. [S1063-651X(99)03610-7]....

  15. Out-of-hospital cardiac arrests in children and adolescents

    DEFF Research Database (Denmark)

    Rajan, Shahzleen; Wissenberg, Mads; Folke, Fredrik;

    2015-01-01

    BACKGROUND: There is insufficient knowledge of out-of-hospital cardiac arrest (OHCA) in the very young. OBJECTIVES: This nationwide study sought to examine age-stratified OHCA characteristics and the role of parental socioeconomic differences and its contribution to mortality in the young...

  16. Chemical Society Reinstates Iranian Chemists; Iranian-American Scholar Arrested

    Science.gov (United States)

    Bollag, Burton

    2007-01-01

    The frosty relationship between the United States and Iran has created a chill in many areas of scholarly endeavor. One resulting battle, over whether Iranian scholars can belong to the American Chemical Society, has been largely resolved. But a new imbroglio looms with the arrest of a prominent U.S.-Iranian scholar who was visiting Tehran. The…

  17. Parenting and Women Arrested for Intimate Partner Violence

    Science.gov (United States)

    Simmons, Catherine A.; Lehmann, Peter; Dia, David A.

    2010-01-01

    Exploring the relationship between parenting and women's use of violence the current study surveyed 106 mothers arrested for intimate partner violence (IPV) related crimes on parenting styles and attitudes toward when using violence against their partner is justified. Findings indicate parenting styles indicative of low belief in using physical…

  18. Mechanisms of immunosuppression by organotins : apoptosis vs. proliferative arrest

    NARCIS (Netherlands)

    Gennari, Alessandra

    2001-01-01

    Mechanisms of immunosuppression by organotins-apoptosis vs. proliferative arrest. The organotin compounds di-n-butyltin dichloride (DBTC) and trin-butyltin chloride (TBTC), used as stabilizers and biocides respectively, induce thymus atrophy inhibiting immature thymocyte proliferation. The aim of

  19. U.S. Juvenile Arrests: Gang Membership, Social Class, and Labeling Effects

    Science.gov (United States)

    Tapia, Mike

    2011-01-01

    This study addresses the link between gang membership and arrest frequency, exploring the Gang x Socioeconomic status interaction on those arrests. Notoriously poor, delinquent, and often well-known to police, America's gang youth should have very high odds of arrest. Yet it is unclear whether mere membership in a gang increases the risk of arrest…

  20. 8 CFR 287.3 - Disposition of cases of aliens arrested without warrant.

    Science.gov (United States)

    2010-01-01

    ... satisfied that there is prima facie evidence that the arrested alien was entering, attempting to enter, or... REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.3 Disposition of cases of aliens arrested without warrant... unnecessary delay, the arresting officer, if the conduct of such examination is a part of the duties...

  1. Mechanical cardiopulmonary resuscitation in in-hospital cardiac arrest : a systematic review

    NARCIS (Netherlands)

    Lameijer, Heleen; Immink, Rosa S.; Broekema, Josien J.; Ter Maaten, Jan C.

    2015-01-01

    With increasing rates of in-hospital cardiac arrest, improving resuscitation outcomes is essential. Mechanical chest compressors seem to be related to improved outcome in out-of hospital cardiac arrest; however, the literature on its use in in-hospital cardiac arrest is scarce. We used the Medline p

  2. Gender and Relational-Distance Effects in Arrests for Domestic Violence

    Science.gov (United States)

    Lally, William; DeMaris, Alfred

    2012-01-01

    This study tests two hypotheses regarding factors affecting arrest of the perpetrator in domestic violence incidents. Black's relational-distance thesis is that the probability of arrest increases with increasing relational distance between perpetrator and victim. Klinger's leniency principle suggests that the probability of arrest is lower for…

  3. 30 CFR 77.508-1 - Lightning arresters; wires entering buildings.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lightning arresters; wires entering buildings... OF UNDERGROUND COAL MINES Electrical Equipment-General § 77.508-1 Lightning arresters; wires entering buildings. Lightning arresters protecting exposed telephone wires entering buildings shall be provided...

  4. 30 CFR 75.521 - Lightning arresters; ungrounded and exposed power conductors and telephone wires.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lightning arresters; ungrounded and exposed... Electrical Equipment-General § 75.521 Lightning arresters; ungrounded and exposed power conductors and... leads underground shall be equipped with suitable lightning arresters of approved type within 100...

  5. 30 CFR 77.508 - Lightning arresters, ungrounded and exposed power conductors and telephone wires.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lightning arresters, ungrounded and exposed... arresters, ungrounded and exposed power conductors and telephone wires. All ungrounded, exposed power conductors and telephone wires shall be equipped with suitable lightning arresters which are...

  6. 10 CFR 1049.6 - Exercise of arrest authority-Use of non-deadly force.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Exercise of arrest authority-Use of non-deadly force. 1049... OF FORCE BY PROTECTIVE FORCE OFFICERS OF THE STRATEGIC PETROLEUM RESERVE § 1049.6 Exercise of arrest authority—Use of non-deadly force. (a) When a Protective Force Officer is authorized to make an arrest...

  7. 10 CFR 1049.7 - Exercise of arrest authority-Use of deadly force.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Exercise of arrest authority-Use of deadly force. 1049.7 Section 1049.7 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) LIMITED ARREST AUTHORITY AND USE OF FORCE BY PROTECTIVE FORCE OFFICERS OF THE STRATEGIC PETROLEUM RESERVE § 1049.7 Exercise of arrest...

  8. Association of national initiatives to improve cardiac arrest management with rates of bystander intervention and patient survival after out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Wissenberg, Mads; Lippert, Freddy K.; Folke, Fredrik;

    2013-01-01

    resuscitation was attempted were identified between 2001 and 2010 in the nationwide Danish Cardiac Arrest Registry. Of 29 111 patients with cardiac arrest, we excluded those with presumed noncardiac cause of arrest (n = 7390) and those with cardiac arrests witnessed by emergency medical services personnel (n......IMPORTANCE Out-of-hospital cardiac arrest is a major health problem associated with poor outcomes. Early recognition and intervention are critical for patient survival. Bystander cardiopulmonary resuscitation (CPR) is one factor among many associated with improved survival. OBJECTIVE To examine...... temporal changes in bystander resuscitation attempts and survival during a 10-year period in which several national initiatives were taken to increase rates of bystander resuscitation and improve advanced care. DESIGN, SETTING, AND PARTICIPANTS Patients with out-of-hospital cardiac arrest for which...

  9. EMERGING TECHNOLOGY BULLETIN: SPOUTED BED REACTOR

    Science.gov (United States)

    The Spouted Bed Reactor (SBR) technology utilizes the unique attributes of the "spouting " fluidization regime, which can provide heat transfer rates comparable to traditional fluid beds, while providing robust circulation of highly heterogeneous solids, concurrent with very agg...

  10. [Historical analysis of the hospital bed].

    Science.gov (United States)

    Fajardo-Ortiz, Guillermo; Fajardo-Dolci, Germán

    2010-01-01

    Until now the bed has been the basic physical resource in hospitals. This type of furniture has served to study and treat patients, through out the centuries it has undergone changes in the materials they are made of dimensions, functionality, accessories, aesthetic, and design. The hospital bed history is not well known, there are thousands of documents about the evolution of hospitals, but not enough is known about hospital beds, a link between the past and the present. The medical, anthropological, technological, social, and economic dynamics and knowledge have produced a variety of beds in general and hospital beds in particular. From instinctive, rustic, poor and irregular "sites" that have differed in shape and size they had evolved into ergonomic equipment. The history of the hospital bed reflects the culture, techniques and human thinking. Current hospital beds include several types: for adults, for children, for labor, for intensive therapy, emergency purposes, census and non census beds etc.

  11. Chinese Bedding Technology Standard under Drafting

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    National Home Textile Standardization Technology Committee(NHTSTC)set up its Bedding Branch Committee. This will promote the work of Chinese bedding technology standardization and a symbol that China step up to meet the

  12. Fluidized Bed Reactor as Solid State Fermenter

    OpenAIRE

    Krishnaiah, K.; Janaun, J.; Prabhakar, A.

    2005-01-01

    Various reactors such as tray, packed bed, rotating drum can be used for solid-state fermentation. In this paper the possibility of fluidized bed reactor as solid-state fermenter is considered. The design parameters, which affect the performances are identified and discussed. This information, in general can be used in the design and the development of an efficient fluidized bed solid-state fermenter. However, the objective here is to develop fluidized bed solid-state fermenter for palm kerne...

  13. Bed Bug Education for School Maintenance

    Science.gov (United States)

    Henriksen, Missy

    2012-01-01

    Bed bugs are a growing problem, not only in homes and hotels, but also in schools and colleges. Facility administrators and staff need to understand the bed bug resurgence and develop best practices to deal with an infestation. In this article, the author offers tips for preventing and treating bed bugs in school and university settings.

  14. 21 CFR 868.5180 - Rocking bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Rocking bed. 868.5180 Section 868.5180 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5180 Rocking bed. (a) Identification. A rocking bed is a...

  15. Thermal Arrest Memory Effect in Ni-Mn-Ga Alloys

    Directory of Open Access Journals (Sweden)

    A. Rudajevova

    2008-01-01

    Full Text Available Dilatation characteristics were measured to investigate the thermal arrest memory effect in Ni53.6Mn27.1Ga19.3 and Ni54.2Mn29.4Ga16.4 alloys. Interruption of the martensite-austenite phase transformation is connected with the reduction of the sample length after thermal cycle. If a total phase transformation took place in the complete thermal cycle following the interruption, then the sample length would return to its original length. Analysis of these results has shown that the thermal arrest memory effect is a consequence of a stress-focusing effect and shape memory effect. The stress-focusing effect occurs when the phase transformation propagates radially in a cylindrical sample from the surface, inward to the center. Evolution and release of the thermoelastic deformations in both alloys during heating and cooling are analyzed.

  16. Arrest of rapid crack propagation in polymer pipes

    Energy Technology Data Exchange (ETDEWEB)

    Flueler, P.; Farshad, M. [EMPA, Duebendorf (Switzerland)

    1995-12-31

    The design of rapid crack arresters for polymer pipes was studied. Mechanisms that would inhibit a running crack and strengthen existing pipes against dynamic fracture and to enhance their degree of safety were examined. The crack arresters examined were based on the principle that rapid crack propagation (RCP) could not occur in pipe walls that were less than a `critical thickness`. Sections of pipe whose walls were thinned were reinforced with a reinforcing ring. Another variation was to produce a pipe with partially adhered multilayer walls. A third variation tried was a multi-layer pipe segment with a damping element and reinforcing rings. Experiments were successful in reducing RCP, but these preliminary results were considered exploratory and would require further confirmation. 2 figs., 8 refs.

  17. Cell cycle control after DNA damage: arrest, recovery and adaptation

    International Nuclear Information System (INIS)

    DNA damage triggers surveillance mechanisms, the DNA checkpoints, that control the genome integrity. The DNA checkpoints induce several responses, either cellular or transcriptional, that favor DNA repair. In particular, activation of the DNA checkpoints inhibits cell cycle progression in all phases, depending on the stage when lesions occur. These arrests are generally transient and cells ultimately reenter the cell division cycle whether lesions have been repaired (this process is termed 'recovery') or have proved un-repairable (this option is called 'adaptation'). The mechanisms controlling cell cycle arrests, recovery and adaptation are largely conserved among eukaryotes, and much information is now available for the yeast Saccharomyces cerevisiae, that is used as a model organism in these studies. (author)

  18. Arresting Strategy Based on Dynamic Criminal Networks Changing over Time

    Directory of Open Access Journals (Sweden)

    Junqing Yuan

    2013-01-01

    Full Text Available We investigate a sequence of dynamic criminal networks on a time series based on the dynamic network analysis (DNA. According to the change of networks’ structure, networks’ variation trend is analyzed to forecast its future structure. Finally, an optimal arresting time and priority list are designed based on our analysis. Better results can be expected than that based on social network analysis (SNA.

  19. Comments on metal oxide surge arresters surges energy absorption capacity

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, M.L.B. [Escola Federal de Engenharia de Itajuba, Minas Gerais (Brazil); Zanetta, L.C. Jr. [E. Politecnica Univ. de Sao Paulo, Sao Paulo (Brazil)

    1996-12-31

    This paper presents an approach to determine the energy absorption capacity of metal oxide surge arrester resistors. The proposed approach deals with the discharge current peak versus discharge current time relation. A testing method and a statistical evaluation are proposed. After determining the discharge current withstanding limit of the tested metal oxide resistors, the prospective energy absorption capacity limit is computed. Finally, comments on the obtained results are presented.

  20. Hyperoxia toxicity after cardiac arrest: What is the evidence?

    OpenAIRE

    Llitjos, Jean-François; Mira, Jean-Paul; Duranteau, Jacques; Cariou, Alain

    2016-01-01

    This review gives an overview of current knowledge on hyperoxia pathophysiology and examines experimental and human evidence of hyperoxia effects after cardiac arrest. Oxygen plays a pivotal role in critical care management as a lifesaving therapy through the compensation of the imbalance between oxygen requirements and supply. However, growing evidence sustains the hypothesis of reactive oxygen species overproduction-mediated toxicity during hyperoxia, thus exacerbating organ failure by vari...

  1. Patients with polycystic ovary syndrome have successful embryo arrest

    OpenAIRE

    Yin, Baoli; Hao, Haoying; Wei, Duo; Song, Xiaobing; Xie, Juanke; Zhang, Cuilian

    2015-01-01

    In this retrospective study, we investigate the relationship between embryo arrest and polycystic ovary syndrome (PCOS) during in vitro fertilization-embryo transfer (IVF-ET). In this study, 667 subjects were enrolled, including 330 patients with PCOS and 337 subjects without PCOS. The subjects underwent in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET) cycles at the Reproductive Medical Centre of Henan Provincial Hospital from January 2009 to December ...

  2. ADULTHOOD ANIMAL ABUSE AMONG MEN ARRESTED FOR DOMESTIC VIOLENCE

    OpenAIRE

    Febres, Jeniimarie; Brasfield, Hope; Shorey, Ryan C.; Elmquist, Joanna; Ninnemann, Andrew; Schonbrun, Yael C.; Temple, Jeff R.; Recupero, Patricia R.; Stuart, Gregory L.

    2014-01-01

    Learning more about intimate partner violence (IPV) perpetrators could aid the development of more effective treatments. The prevalence of adulthood animal abuse (AAA) perpetration and its association with IPV perpetration, antisociality, and alcohol use in 307 men arrested for domestic violence was examined. 41% (n = 125) of the men committed at least one act of animal abuse since the age of 18, in contrast to the 3.0% prevalence rate reported by men in the general population. Controlling fo...

  3. Nontrapping arrest of Langmuir wave damping near the threshold amplitude

    OpenAIRE

    Ivanov, A.V.; Cairns, Iver H.

    2005-01-01

    Evolution of a Langmuir wave is studied numerically for finite amplitudes slightly above the threshold which separates damping from nondamping cases. Arrest of linear damping is found to be a second-order effect due to ballistic evolution of perturbations, resonant power transfer between field and particles, and organization of phase space into a positive slope for the average distribution function $f_{av}$ around the resonant wave phase speed $v_\\phi$. Near the threshold trapping in the wave...

  4. Anaphylactic shock and cardiac arrest caused by thiamine infusion

    OpenAIRE

    Juel, Jacob; Pareek, Manan; Langfrits, Christian Sigvald; Jensen, Svend Eggert

    2013-01-01

    Parenteral thiamine has a very high safety profile. The most common adverse effect is local irritation; however, anaphylactic or anaphylactoid reactions may occur, mostly related to intravenous administration. We describe a 44-year-old man, a chronic alcoholic, who was admitted with alcohol intoxication and developed cardiac arrest due to anaphylactic shock following intravenous thiamine infusion. The patient was successfully resuscitated after 15 min and repeated epinephrine administrations....

  5. Luminescence from Tube-Arrest Bubbles in Pure Glycerin

    Institute of Scientific and Technical Information of China (English)

    陈岐岱; 王龙

    2004-01-01

    Single transient cavitation bubble with luminescence has been generated in pure glycerin by using the ‘tube arrest'method. The analyses of high-speed photograph and light emission data suggest that the light emission would be a single bubble sonoluminescence. The luminescence pulse width is observed to wry from sub-nanosecond to about 30 ns. The width and intensity of luminescence pulses increases with the height of the liquid column height and decreases with the liquid temperature.

  6. Characteristics of in-hospital cardiac arrest and cardiopulmonary resuscitation

    Directory of Open Access Journals (Sweden)

    Josip Ivić

    2009-02-01

    Full Text Available Aim We have studied epidemiology of in-hospital cardiac arrest, characteristics of organizing a reanimationand its,procedures as well as its documenting.Methods We analyzed all resuscitation procedure data where anesthesiology reanimation teams (RT providedcardiopulmonary resuscitation (CPR during one-year period. We included resuscitation attemptsthat were initiated outside the Department of Anesthesiology, excluding incidents in operation rooms andIntensive Care Unit (ICU. Data on every cardiac arrest and CPR were entered in a special form.Results During one-year period 87 CPR were performed. Victims of cardiac arrest were principallyelderly patients (age 60 – 80, mostly male (60%. Most frequent victims were neurological patients(42%, surgical patients (21% and neurosurgical patients (10%. The leading cause of cardiac arrestwas primary heart disease, following neurological diseases and respiration disorders of severe etiology.In over 90% cases CPR was initiated by medical personnel in their respective departments, RT arrivedwithin 5 minutes in 73,56% cases. Initially survival was 32%, but full recovery was accomplished in 4patients out of 87 (4,6%.Conclusion Victims of cardiac arrest are patients whose primary disease contributes to occurrence ofcardiorespiratory complications. High mortality and low percentage of full recovery can be explainedby characteristics of patients (old age, nature and seriousness of primary disease which significantly affectthe outcome of CPR. In some cases a question is raised whether to initiate the CPR at all. We wouldlike to point out that continous monitoring of potentially critical patients may prevent cardiorespiratoryincidents whereas the quality and success of CPR may be improved by training of staff and better technicalequipment on the relevant locations in the in the hospital where such incidents usually occur.

  7. Crack arrest saturation model under combined electrical and mechanical loadings

    Directory of Open Access Journals (Sweden)

    R.R. Bhargava

    2009-12-01

    Full Text Available Purpose: The investigation aims at proposing a model for cracked piezoelectric strip which is capable to arrest the crack.Design/methodology/approach: Under the combined effect of electrical and mechanical loadings applied at the edges of the strip, the developed saturation zone is produced at each tip of the crack. To arrest further opening of the crack, the rims of the developed saturation zones are subjected to in-plane cohesive, normal uniform constant saturation point electrical displacement. The problem is solved using Fourier integral transform method which reduces the problem to the solution of Fredholm integral equation of the second kind. This integral equation in turn is solved numerically.Findings: The expressions are derived for different intensity factors and energy release rate. A qualitative analysis of the parameters affecting the arrest of opening of the crack and fatigue crack growth with respect to strip thickness and material constants are presented graphically.Research limitations/implications: The investigations are carried out by considering the material electrical brittle. Consequently, the zones protrude along the straight lines ahead of the crack tips. And further, the small scale electrical yielding conditions are used.Practical implications: Piezoelectric materials are widely getting used nowadays, even in day to day life like piezoelectric cigarette lighter, children toys etc. And, its advance used in technology like transducers, actuators has been already in progress. So, the aspect of cracking of piezoelectric materials are of great practical importance.Originality/value: The piezoelectric material under the combined effect of electrical and mechanical loadings gives the assessment of electrical displacement which is required to arrest the crack. The various useful interpretations are also drawn from the graphs.

  8. Review of acute cancer beds.

    LENUS (Irish Health Repository)

    Evans, D S

    2012-01-01

    A review of admissions to cancer services at University Hospital Galway (UHG) was undertaken to assess the appropriateness of hospital usage. All cancer specialty patients admitted from 26-28 May 2009 were reviewed (n = 82). Chi square tests, Exact tests, and One-way ANOVA were utilised to analyse key issues emerging from the data. Fifty (61%) were classified as emergencies. Twenty three (67%) occupied a designated cancer bed with 24 (30%) in outlying non-oncology wards. The mean length of stay was 29.3 days. Possible alternatives to admission were identified for 15 (19%) patients. There was no evidence of discharge planning for 50 (60%) admissions. There is considerable potential to make more appropriate utilisation of UHG for cancer patients, particularly in terms of reducing bed days and length of stay and the proportion of emergency cancer admissions, and further developing integrated systems of discharge planning.

  9. Bed bathing patients in hospital

    OpenAIRE

    L Downey; Lloyd, Hilary

    2008-01-01

    There are a number of circumstances that may affect an individual's ability to maintain personal hygiene. Hospitalised patients, and in particular those who are bedridden, may become dependent on nursing staff to carry out their hygiene needs. Assisting patients to maintain personal hygiene is a fundamental aspect of nursing care. However, it is a task often delegated to junior or newly qualified staff. This article focuses on the principles of bed bathing patients in hospital, correct proced...

  10. THE BAUXITES AND JELAR - BEDS

    Directory of Open Access Journals (Sweden)

    Krešimir Sakač

    1993-12-01

    Full Text Available Minor bauxite deposits and occurrences were formed in technically disturbed environments in the middle part of the Adriatic geotectonic unit in Dinarides, contemporary with the clastic Jelar-beds in the Late Lutetian time. Uneven chemical composition of these Eocene bauxites, their sporadic occurrences in developed paleorelief as well as characteristic petrographic composition of the immediate overlying rocks point out at different genetical conditions (the paper is published in Croatian.

  11. Solids mixing in spouted beds

    OpenAIRE

    Cook, H. H.; Bridgwater, J.; Professor J. Bridgwater

    1981-01-01

    Many industrial processes require contact between particles and a fluid or spray in order to effect drying, coating or granulation. One device capable of contacting fluid and particles efficiently is a spouted bed in which a jet of fluid is injected into solid particles. This forms an open channel or spout and induces material circulation in a downward moving annulus. For the continuous throughput of solids, knowledge is required of the mixing and particle motions within th...

  12. Advances in crack-arrest technology for reactor pressure vessels

    Energy Technology Data Exchange (ETDEWEB)

    Bass, B.R.; Pugh, C.E.

    1988-01-01

    The Heavy-Section Steel Technology (HSST) Program at the Oak Ridge National Laboratory (ORNL) under the sponsorship of the US Nuclear Regulatory Commission is continuing to improve the understanding of conditions that govern the initiation, rapid propagation, arrest, and ductile tearing of cracks in reactor pressure vessel (RPV) steels. This paper describes recent advances in a coordinated effort being conducted under the HSST Program by ORNL and several subcontracting groups to develop the crack-arrest data base and the analytical tools required to construct inelastic dynamic fracture models for RPV steels. Large-scale tests are being carried out to generate crack-arrest toughness data at temperatures approaching and above the onset of Charpy upper-shelf behavior. Small- and intermediate-size specimens subjected to static and dynamic loading are being developed and tested to provide additional fracture data for RPV steels. Viscoplastic effects are being included in dynamic fracture models and computer programs and their utility validated through analyses of data from carefully controlled experiments. Recent studies are described that examine convergence problems associated with energy-based fracture parameters in viscoplastic-dynamic fracture applications. Alternative techniques that have potential for achieving convergent solutions for fracture parameters in the context of viscoplastic-dynamic models are discussed. 46 refs., 15 figs., 3 tabs.

  13. Hyperoxia toxicity after cardiac arrest: What is the evidence?

    Science.gov (United States)

    Llitjos, Jean-François; Mira, Jean-Paul; Duranteau, Jacques; Cariou, Alain

    2016-12-01

    This review gives an overview of current knowledge on hyperoxia pathophysiology and examines experimental and human evidence of hyperoxia effects after cardiac arrest. Oxygen plays a pivotal role in critical care management as a lifesaving therapy through the compensation of the imbalance between oxygen requirements and supply. However, growing evidence sustains the hypothesis of reactive oxygen species overproduction-mediated toxicity during hyperoxia, thus exacerbating organ failure by various oxidative cellular injuries. In the cardiac arrest context, evidence of hyperoxia effects on outcome is fairly conflicting. Although prospective data are lacking, retrospective studies and meta-analysis suggest that hyperoxia could be associated with an increased mortality. However, data originate from retrospective, heterogeneous and inconsistent studies presenting various biases that are detailed in this review. Therefore, after an original and detailed analysis of all experimental and clinical studies, we herein provide new ideas and concepts that could participate to improve knowledge on oxygen toxicity and help in developing further prospective controlled randomized trials on this topic. Up to now, the strategy recommended by international guidelines on cardiac arrest (i.e., targeting an oxyhemoglobin saturation of 94-98 %) should be applied in order to avoid deleterious hypoxia and potent hyperoxia. PMID:27003426

  14. Isolation Syndrome after Cardiac Arrest and Therapeutic Hypothermia.

    Science.gov (United States)

    Forgacs, Peter B; Fridman, Esteban A; Goldfine, Andrew M; Schiff, Nicholas D

    2016-01-01

    Here, we present the first description of an isolation syndrome in a patient who suffered prolonged cardiac arrest and underwent a standard therapeutic hypothermia protocol. Two years after the arrest, the patient demonstrated no motor responses to commands, communication capabilities, or visual tracking at the bedside. However, resting neuronal metabolism and electrical activity across the entire anterior forebrain was found to be normal despite severe structural injuries to primary motor, parietal, and occipital cortices. In addition, using quantitative electroencephalography, the patient showed evidence for willful modulation of brain activity in response to auditory commands revealing covert conscious awareness. A possible explanation for this striking dissociation in this patient is that altered neuronal recovery patterns following therapeutic hypothermia may lead to a disproportionate preservation of anterior forebrain cortico-thalamic circuits even in the setting of severe hypoxic injury to other brain areas. Compared to recent reports of other severely brain-injured subjects with such dissociation of clinically observable (overt) and covert behaviors, we propose that this case represents a potentially generalizable mechanism producing an isolation syndrome of blindness, motor paralysis, and retained cognition as a sequela of cardiac arrest and therapeutic hypothermia. Our findings further support that highly-preserved anterior cortico-thalamic integrity is associated with the presence of conscious awareness independent from the degree of injury to other brain areas. PMID:27375420

  15. The statistical character of packed-bed heat transport properties

    OpenAIRE

    Wijngaarden, R.J.; Westerterp, K. R.

    1992-01-01

    Packed beds are essentially heterogeneous on a pellet scale. For random packed beds this heterogeneity causes a statistical character both on a pellet and bed scale. We discuss experimental results which deal with bed-scale statistics.

  16. Method and apparatus for a combination moving bed thermal treatment reactor and moving bed filter

    Energy Technology Data Exchange (ETDEWEB)

    Badger, Phillip C.; Dunn, Jr., Kenneth J.

    2015-09-01

    A moving bed gasification/thermal treatment reactor includes a geometry in which moving bed reactor particles serve as both a moving bed filter and a heat carrier to provide thermal energy for thermal treatment reactions, such that the moving bed filter and the heat carrier are one and the same to remove solid particulates or droplets generated by thermal treatment processes or injected into the moving bed filter from other sources.

  17. Equilibrium bed-concentration of nonuniform sediment

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Knowledge of the equilibrium bed-concentration is vital to mathematical modeling of the river-bed deformation associated with suspended load but previous investigations only dealt with the reference concentration of uniform sediment because of difficulties in observation of the bed-concentration. This work is a first attempt to develop a theoretical formula for the equilibrium bed-concentration of any fraction of nonuniform sediment defined at the bed-surface. The formula is based on a stochastic-mechanistic model for the exchange of nonuniform sediment near the bed, and described as a function of incipient motion probability, non-ceasing probability, pick-up probability, and the ratio of the average single-step continuous motion time to static time. Comparison of bed-concentration calculated from the proposed formula with the measured data showed satisfactory agreement, indicating the present formula can be used for solving the differential equation governing the motion of suspended load.

  18. Descriptive Analysis of Medication Administration During Inpatient Cardiopulmonary Arrest Resuscitation (from the Mayo Registry for Telemetry Efficacy in Arrest Study).

    Science.gov (United States)

    Snipelisky, David; Ray, Jordan; Matcha, Gautam; Roy, Archana; Dumitrascu, Adrian; Harris, Dana; Bosworth, Veronica; Clark, Brooke; Thomas, Colleen S; Heckman, Michael G; Vadeboncoeur, Tyler; Kusumoto, Fred; Burton, M Caroline

    2016-05-15

    Advanced cardiovascular life support guidelines exist, yet there are variations in clinical practice. Our study aims to describe the utilization of medications during resuscitation from in-hospital cardiopulmonary arrest. A retrospective review of patients who suffered a cardiopulmonary arrest from May 2008 to June 2014 was performed. Clinical and resuscitation data, including timing and dose of medications used, were extracted from the electronic medical record and comparisons made. A total of 94 patients were included in the study. Patients were divided into different groups based on the medication combination used during resuscitation: (1) epinephrine; (2) epinephrine and bicarbonate; (3) epinephrine, bicarbonate, and calcium; (4) epinephrine, bicarbonate, and epinephrine drip; and (5) epinephrine, bicarbonate, calcium, and epinephrine drip. No difference in baseline demographics or clinical data was present, apart from history of dementia and the use of calcium channel blockers. The number of medications given was correlated with resuscitation duration (Spearman's rank correlation = 0.50, p <0.001). The proportion of patients who died during the arrest was 12.5% in those who received epinephrine alone, 30.0% in those who received only epinephrine and bicarbonate, and 46.7% to 57.9% in the remaining groups. Patients receiving only epinephrine had shorter resuscitation durations compared to that of the other groups (p <0.001) and improved survival (p = 0.003). In conclusion, providers frequently use nonguideline medications in resuscitation efforts for in-hospital cardiopulmonary arrests. Increased duration and mortality rates were found in those resuscitations compared with epinephrine alone, likely due to the longer resuscitation duration in the former groups. PMID:27015887

  19. Arrest of Avalanche Propagation by Discontinuities on Snow Cover

    Science.gov (United States)

    Frigo, B.; Chiaia, B.

    2009-04-01

    Considering the spatial variability of the snow cover, the paper analyses, in the framework of Fracture Mechanics, the Mode II fracture propagation on snow cover that leads to large dry slab avalanches. Under the hypothesis of a perfectly brittle phenomenon, avalanche triggering is usually investigated numerically by means of Linear Elastic Fracture Mechanics (McClung, 1979; Chiaia et al., 2008). Since, however, the real phenomenon is intrinsically dynamical, another aspect to investigate is represented by dynamic fracture propagation. In this paper, we model dynamic crack propagation into a dry snow slab, to assess the possibility of crack arrest due to the presence of weak zones distributed along the snow slope. As a consequence of the first triggering mechanism (the Mode II fracture propagation on the weak plane), the secondary Mode I crack propagation in the crown is studied by means of numerical simulations based on Dynamic Elastic Fracture Mechanics and on the theory of crack arresters. By taking into account kinetic energy and using the FEM software FRANC 2D (Wawrzynek and Ingraffea, 1993), several paths of crown fracture propagation and their stability have been investigated. The snowpack is considered as a linear-elastic plate (2D problem), whose physical and mechanical parameters are chosen according to classical literature values. To investigate the possible arrest of crown fracture, we apply the theory of crack arresters, usually adopted for pipelines and perforated steel sheets fracture problems. To study crack arrest, different crack paths are simulated, in discontinuous (equipped with different shapes and geometries of artificial voids) snowpacks. The simulations show the effectiveness of these weak zones, to reduce substantially the crack driving force of the propagating fracture. This means that, increasing spatial variability tends to stabilize the snow slope, eventually splitting a major avalanche event into smaller, independent avalanches. Our

  20. The Berlin emissivity database (BED)

    Science.gov (United States)

    Maturilli, A.; Helbert, J.; Moroz, L.

    2008-03-01

    Remote-sensing infrared spectroscopy is the principal field of investigation for planetary surfaces composition. Past, present and future missions to the solar system bodies include in their payload, instruments measuring the emerging radiation in the infrared range. Apart from measuring the reflected radiance, more and more spacecrafts are equipped with instruments measuring directly the emitted radiation from the planetary surface. The emitted radiation is not only a function of the composition of the material but also of its texture and especially the grain size distribution. For the interpretation of the measured data an emissivity spectral library of planetary analogue materials in grain size fractions appropriate for planetary surfaces is needed. The Berlin emissivity database (BED) presented here is focused on relatively fine-grained size separates, providing thereby a realistic basis for the interpretation of thermal emission spectra of planetary regoliths. The BED is therefore complimentary to existing thermal emission libraries, like the ASU library for example. BED currently contains emissivity spectra of plagioclase and potassium feldspars, low Ca and high Ca pyroxenes, olivine, elemental sulfur, Martian analogue minerals and volcanic soils, and a lunar highland soil sample measured in the wavelength range from 7 to 22 μm as a function of particle size. For each sample we measured the spectra of four particle size separates ranging from <25 to 250 μm. The device we used is built at DLR (Berlin) and is coupled to a Fourier-transform infrared spectrometer Bruker IFS 88 purged with dry air and equipped with a nitrogen-cooled MCT detector. All spectra were acquired with a spectral resolution of 4 cm -1. We are currently working on upgrading our emissivity facility. A new spectrometer (Bruker VERTEX 80 V) and new detectors will allow us to measure the emissivity of samples in the wavelength range from 1 to 50 μm in a vacuum environment. This will be

  1. MICROTURBULENCE IN GRAVEL BED STREAMS

    Science.gov (United States)

    Papanicolaou, T.; Tsakiris, A. G.; Kramer, C. M.

    2009-12-01

    The overarching objective of this investigation was to evaluate the role of relative submergence on the formation and evolution of cluster microforms in gravel bed streams and its implications to bedload transport. Secondary objectives of this research included (1) a detailed analysis of mean flow measurements around a clast; and (2) a selected number of experimental runs where the mean flow characteristics are linked together with the bed micro-topography observations around a clast. It is hypothesized that the relative submergence is an important parameter in defining the feedback processes between the flow and clasts, which governs the flow patterns around the clasts, thus directly affecting the depositional patterns of the incoming sediments. To examine the validity of the hypothesis and meet the objectives of this research, 19 detailed experimental runs were conducted in a tilting, water recirculating laboratory flume under well-controlled conditions. A fixed array of clast-obstacles were placed atop a well-packed bed with uniform size glass beads. During the runs, multifractional spherical particles were fed upstream of the clast section at a predetermined rate. State-of-the-art techniques/instruments, such as imaging analysis software, Large Scale Particle Velocimeter (LSPIV) and an Acoustic Doppler Velocimetry (ADV) were employed to provide unique quantitative measurements for bedload fluxes, clast/clusters geomorphic patterns, and mean flow characteristics in the vicinity of the clusters. Different flow patterns were recorded for the high relative submergence (HRS) and low relative submergence (LRS) experimental runs. The ADV measurements provided improved insight about the governing flow mechanisms for the HRS runs. These mechanisms were described with flow upwelling at the center of the flume and downwelling occurring along the flume walls. Flow downwelling corresponded to an increase in the free surface velocity. Additionally, the visual observations

  2. [Special beds. Pulmonary therapy system].

    Science.gov (United States)

    Calixto Rodríguez, Joaquín; Rodríguez Martínez, Xavier; Marín i Vivó, Gemma; Paunellas Albert, Josep

    2008-10-01

    To be bedridden reduces one's capacity to move and produces muscular debility that affects the respiratory system leading to a decreased effectiveness in expectoration, the ability to spit up sputum. The pulmonary therapy system integrated in a bed is the result of applying motorized elements to the articulation points of the bad in order to achieve safe positions at therapeutic angles, which improve the breathing-perfusion (blood flow) relationship. This system also makes it possible to apply vibration waves to the patient which favor the elimination of bronchial-pulmonary secretions, the rehabilitation of the bedridden patient and decrease the work load for nursing personnel.

  3. [Ethics of organ retrieval after controlled cardiac arrest].

    Science.gov (United States)

    Kinnaert, P

    2011-01-01

    The article tells the evolution of the terminology concerning non heart beating donors during the two last decades and describes summarily the procedure of organ retrieval after controlled cardiac arrest. We then consider the various ethical problems created by this practice. We discuss in detail therapeutic withdrawal, the treatment of the donor during the agonal period, death certification, the doctor's conflict of interests, the presence of the family at the time of death, the quality of the organs and organ retrieval after euthanasia. PMID:22279852

  4. Axial crack propagation and arrest in pressurized fuselage

    Science.gov (United States)

    Kosai, M.; Shimamoto, A.; Yu, C.-T.; Walker, S. I.; Kobayashi, A. S.; Tan, P.

    1994-01-01

    The crack arrest capability of a tear strap in a pressurized precracked fuselage was studied through instrumented axial rupture tests of small scale models of an idealized fuselage. Upon pressurization, rapid crack propagation initiated at an axial through crack along the stringer and immediately kinked due to the mixed modes 1 and 2 state caused by the one-sided opening of the crack flap. The diagonally running crack further turned at the tear straps. Dynamic finite element analysis of the rupturing cylinder showed that the crack kinked and also ran straight in the presence of a mixed mode state according to a modified two-parameter crack kinking criterion.

  5. Cardiac arrest caused by multiple recurrent pulmonary embolism

    DEFF Research Database (Denmark)

    Hannig, Kjartan Eskjaer; Husted, Steen Elkjaer; Grove, Erik Lerkevang

    2011-01-01

    Pulmonary embolism is a common condition with a high mortality. We describe a previously healthy 68-year-old male who suffered three pulmonary embolisms during a short period of time, including two embolisms while on anticoagulant treatment. This paper illustrates three important points. (1) The ...... and may be life-saving in patients with cardiac arrest suspected to be caused by pulmonary embolism.......) The importance of optimal anticoagulant treatment in the prevention of pulmonary embolism reoccurrence. (2) The benefit of immediate accessibility to echocardiography in the handling of haemodynamically unstable patients with an unknown underlying cause. (3) Thrombolytic treatment should always be considered...

  6. The inflammatory marker suPAR after cardiac arrest

    DEFF Research Database (Denmark)

    Rundgren, Malin; Lyngbaek, Stig; Fisker, Helle;

    2015-01-01

    BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is released in response to inflammatory stimuli, and plasma levels are associated with long-term outcomes. The ischemia/reperfusion injury caused by cardiac arrest (CA) and resuscitation triggers an inflammatory response...... analysis shoved an AUC of 0.76 at 6 hours. In the subgroup of CA of cardiac cause, the AUC was 0.84. CONCLUSION: suPAR levels at 6 and 36 hours after CA were significantly higher in nonsurviving patients compared with survivors; however, the overlap in suPAR levels between the outcome groups...

  7. Case study: flame arresters and exploding gasoline containers.

    Science.gov (United States)

    Hasselbring, Lori C

    2006-03-17

    This paper describes the case study of a portable plastic gasoline container explosion and fire. While working at home on a science project to determine the burn rates of different types of wood fuel, a 14-year-old boy was severely burned after flames traveled back up into the portable gasoline container and exploded. A witness heard the explosion and reports that the flames went perhaps 10 ft in the air. It is shown by experimentation that a flame arrester installed in the pour opening of the portable gasoline container would have prevented an explosion inside the gasoline container.

  8. Bleeding following deep hypothermia and circulatory arrest in children.

    Science.gov (United States)

    Mossad, Emad B; Machado, Sandra; Apostolakis, John

    2007-03-01

    Deep hypothermic circulatory arrest (DHCA) is a technique of extracorporeal circulation commonly used in children with complex congenital heart defects undergoing surgical repairs. The use of profound cooling (20 degrees C) and complete cessation of circulation allow adequate exposure and correction of these complex lesions, with enhanced cerebral protection. However, the profound physiologic state of DHCA results in significant derangement of the coagulation system and a high incidence of postoperative bleeding. This review examines the impact of DHCA on bleeding and transfusion requirements in children and the pathophysiology of DHCA-induced platelet dysfunction. It also focuses on possible pharmacologic interventions to decrease bleeding following DHCA in children. PMID:17484172

  9. Effectiveness of installing two pairs of distribution surge arresters in parallel

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, Hitoshi; Asakawa, Akira; Yokoyama, Shigeru [Central Research Institute of Electric Power Industry (Japan); Nakada, Kazuo [Hokurika Electric Power Co. (Japan)

    1999-07-01

    Lightning strokes with a large amount of energy sometimes occur on the Sea of Japan coast in winter. Winter lightning often damages overhead power distribution lines, in particular, those supplying power to high structures located in mountainous areas. We have investigated that the ratio of surge arrester outages with respect to all damaged installations on such power distribution lines is largest at approximately 50%. We have examined the effectiveness of installing two pairs of surge arresters in parallel on a single pole as a method for preventing distribution surge arrester outages experimentally. We have clarified that to install surge arresters in parallel is effective in reducing the energy absorbed by surge arresters if these surge arresters have almost the same discharge voltage and voltage-current characteristics. (author)

  10. Classifying bed inclination using pressure images.

    Science.gov (United States)

    Baran Pouyan, M; Ostadabbas, S; Nourani, M; Pompeo, M

    2014-01-01

    Pressure ulcer is one of the most prevalent problems for bed-bound patients in hospitals and nursing homes. Pressure ulcers are painful for patients and costly for healthcare systems. Accurate in-bed posture analysis can significantly help in preventing pressure ulcers. Specifically, bed inclination (back angle) is a factor contributing to pressure ulcer development. In this paper, an efficient methodology is proposed to classify bed inclination. Our approach uses pressure values collected from a commercial pressure mat system. Then, by applying a number of image processing and machine learning techniques, the approximate degree of bed is estimated and classified. The proposed algorithm was tested on 15 subjects with various sizes and weights. The experimental results indicate that our method predicts bed inclination in three classes with 80.3% average accuracy.

  11. Gruppebaseret behandling af BED - et faseopdelt behandlingstilbud

    DEFF Research Database (Denmark)

    Laust, Jakob; Lau, Marianne Engelbrecht; Waaddegaard, Mette

    2015-01-01

    Titel: Afrapportering vedr. SATS-puljemidler til behandling og erfaringsopsamling vedr. BED for perioden 1. marts 2013 – 1. maj 2015. Baggrund: Binge Eating Disorder (BED), på dansk tvangsoverspisning, er en udbredt, men overset spiseforstyrrelse med alvorlige psykiske, fysiske og sociale...... konsekvenser. BED blev i 2013 optaget i DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) som en selvstændig diagnose og BED forventes medtaget i den forestående revision af det internationale diagnose system, ICD-11. Sundhedsstyrelsen gav på denne baggrund satspuljemidler til erfaringsopsamling...... vedr. BED. I den forbindelse ansøgte Ambulatorium for Spiseforstyrrelser på Psykoterapeutisk Center Stolpegård ovenstående midler til at udvikle en ambulant, primært psykoterapeutisk gruppebehandling til patienter med moderat til svær BED med fokus på såvel spiseforstyrrelse såvel som overvægt. Metode...

  12. Fluid-bed process for SYNROC production

    International Nuclear Information System (INIS)

    SYNROC is a titanate-based ceramic waste developed for the immobilization of high-level nuclear reactor waste. Lawrence Livermore National Laboratory (LLNL) has investigated a fluid-bed technique for the large-scale production of SYNROC precursor powders. Making SYNROC in a fluid bed permits slurry drying, calcination and reduction-oxidation reactions to be carried out in a single unit. We present the results of SYNROC fluid-bed studies from two fluid-bed units 10 cm in diameter: an internally heated fluid-bed unit developed by Exxon Idaho and an externally heated unit constructed at LLNL. Bed operation over a range of temperatures, feed rates, fluidizing rates, and redox conditions indicate that SYNROC powders of a high density and a uniform particle size can be produced. These powders facilitate the densification step and yield dense ceramics (greater than 95% theoretical density) with well-developed phases and low leaching rates

  13. The WCSAR telerobotics test bed

    Science.gov (United States)

    Duffie, N.; Zik, J.; Teeter, R.; Crabb, T.

    1988-01-01

    Component technologies for use in telerobotic systems for space are being developed. As part of this effort, a test bed was established in which these technologies can be verified and integrated into telerobotic systems. The facility consists of two slave industrial robots, an articulated master arm controller, a cartesian coordinate master arm controller, and a variety of sensors, displays and stimulators for feedback to human operators. The controller of one of the slave robots remains in its commercial state, while the controller of the other robot has been replaced with a new controller that achieves high-performance in telerobotic operating modes. A dexterous slave hand which consists of two fingers and a thumb is being developed, along with a number of force-reflecting and non-force reflecting master hands, wrists and arms. A tactile sensing finger tip based on piezo-film technology has been developed, along with tactile stimulators and CAD-based displays for sensory feedback and sensory substitution. The telerobotics test bed and its component technologies are described, as well as the integration of these component technologies into telerobotic systems, and their performance in conjunction with human operators.

  14. Spring packed particle bed fuel element

    International Nuclear Information System (INIS)

    This patent describes a gas cooled particle bed nuclear fuel element. It comprises: a porous inner frit; a porous outer frit attached to the inner frit by an end cap t a first end and radially guided by a shoulder at a second end, forming an annulus between the frits; a fuel particle bed in the annulus; a first compressive device at each end of the annulus; and a second compressive device positioned in the annulus within the fuel particle bed

  15. Brazilian production development of class 2 polymeric surge arresters for transmission line application

    Energy Technology Data Exchange (ETDEWEB)

    Dellallibera, Adriano A. [Industria Eletromecanica Balestro, Mogi Mirim, SP (Brazil)], E-mail: adrianoad@balestro.com; Andrade, Antonio Donizetti de; Bezerra, Ana Cristina Guara; Duarte, Jose Vicente Pereira; Gois, Paulo Marcio Batista; Markiewicz, Rubens Leopoldo [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil)], Emails: andonize@cemig.com.br, anacris@cemig.com.br, vicente@cemig.com.br, pgois@cemig.com.br, rlmark@cemig.com.br

    2007-07-01

    This paper shows the steeps of Brazilian class 2 ZnO lightning surge arrester development and production, aiming to attend the goal of CEMIG transmission lines performance improvement against lightning discharges action. The description of CEMIG transmission lines performance, before and after the ZnO lightning arresters installation, the necessity of use of ZnO lightning surge arrester, the prototypes manufacture, tests, problems and solutions are presented. (author)

  16. Application and Analysis for Surge Arrester on Lightning Protection of Distribution Network

    Directory of Open Access Journals (Sweden)

    Wang Daxing

    2016-01-01

    Full Text Available In order to effectively reduce lightning stroke outage rate, effect of lightning protection with surge arrester on transmission line has been generally acknowledged relative to other lightning protection measures. This article introduces in such aspects as the working principle of line surge arrester and effect of lightning protection, and also explores application for lightning arrester of distribution network to achieve difference lightning protection and improve the lightning protection performance of distribution network.

  17. Application and Analysis for Surge Arrester on Lightning Protection of Distribution Network

    Directory of Open Access Journals (Sweden)

    Wang Daxing

    2015-01-01

    Full Text Available In order to effectively reduce lightning stroke outage rate, effect of lightning protection with surge arrester on transmission line has been generally acknowledged relative to other lightning protection measures. This article introduces in such aspects as the working principle of line surge arrester and effect of lightning protection, and also explores application for lightning arrester of distribution network to achieve difference lightning protection and improve the lightning protection performance of distribution network.

  18. Crack propagation and arrest in CFRP materials with strain softening regions

    Science.gov (United States)

    Dilligan, Matthew Anthony

    Understanding the growth and arrest of cracks in composite materials is critical for their effective utilization in fatigue-sensitive and damage susceptible applications such as primary aircraft structures. Local tailoring of the laminate stack to provide crack arrest capacity intermediate to major structural components has been investigated and demonstrated since some of the earliest efforts in composite aerostructural design, but to date no rigorous model of the crack arrest mechanism has been developed to allow effective sizing of these features. To address this shortcoming, the previous work in the field is reviewed, with particular attention to the analysis methodologies proposed for similar arrest features. The damage and arrest processes active in such features are investigated, and various models of these processes are discussed and evaluated. Governing equations are derived based on a proposed mechanistic model of the crack arrest process. The derived governing equations are implemented in a numerical model, and a series of simulations are performed to ascertain the general characteristics of the proposed model and allow qualitative comparison to existing experimental results. The sensitivity of the model and the arrest process to various parameters is investigated, and preliminary conclusions regarding the optimal feature configuration are developed. To address deficiencies in the available material and experimental data, a series of coupon tests are developed and conducted covering a range of arrest zone configurations. Test results are discussed and analyzed, with a particular focus on identification of the proposed failure and arrest mechanisms. Utilizing the experimentally derived material properties, the tests are reproduced with both the developed numerical tool as well as a FEA-based implementation of the arrest model. Correlation between the simulated and experimental results is analyzed, and future avenues of investigation are identified

  19. UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent.

    Science.gov (United States)

    Horst, Jeremy A; Ellenikiotis, Hellene; Milgrom, Peter L

    2016-01-01

    The Food and Drug Administration recently cleared silver diamine fluoride for reducing tooth sensitivity. Clinical trials document arrest and prevention of dental caries by silver diamine fluoride. This off-label use is now permissible and appropriate under U.S. law. A CDT code was approved for caries arresting medicaments for 2016 to facilitate documentation and billing. We present a systematic review, clinical indications, clinical protocol and consent procedure to guide application for caries arrest treatment. PMID:26897901

  20. Developmentally arrested structures preceding cerebellar tumors in von Hippel–Lindau disease

    OpenAIRE

    Shively, Sharon B; Falke, Eric A; Li, Jie; Tran, Maxine G B; Thompson, Eli R; Maxwell, Patrick H; Roessler, Erich; Oldfield, Edward H; Lonser, Russell R.; Vortmeyer, Alexander O

    2011-01-01

    There is increasing evidence that suggests that knockout of tumor-suppressor gene function causes developmental arrest and protraction of cellular differentiation. In the peripheral nervous system of patients with the tumor-suppressor gene disorder, von Hippel–Lindau disease, we have demonstrated developmentally arrested structural elements composed of hemangioblast progenitor cells. Some developmentally arrested structural elements progress to a frank tumor, hemangioblastoma. However, in von...

  1. Metal oxide surge arrester research at the University of South Australia: An evaluation of polymer housed arresters and a new device for condition monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Baghurst, A.H. [Flinders Univ. of South Australia, Bedford Park, SA (Australia); Buratto, F. [Powercor Australia Ltd., Southbank, VIC (Australia); Krieg, T.W. [ETSA Transmission, Adelaide, SA (Australia)

    1995-12-31

    The use of polymer housed surge arresters within Australia has dramatically increased over the last 2-3 years. Unfortunately, the development of standards for testing polymer housed arresters has not kept pace with the development of these components. This paper describes on-going research at the Australian Electrical Testing Centre, University of South Australia, aimed at furthering knowledge about the performance of metal oxide surge arresters in the field. One project seeks to evaluate a range of polymer-housed arresters from different manufacturers with respect to seal integrity and accelerated ageing under a variety of environmental conditions. Test equipment being developed to perform the tests is described, and those parts of the new draft Australia standard relating to the performance of polymer-housed arresters critically reviewed. A second project involves the development of a new hand-held device for the measurement of that component of arrester leakage current which is in phase with the applied voltage. This parameter is widely accepted as a key indicator of the condition of a metal oxide arrester. The new device should be an order of magnitude cheaper than comparable commercial equipment currently available, and employs a micro controller to perform the required signal processing. (author). 1 tab., 2 figs., 11 refs.

  2. Fluidized Bed Reactor as Solid State Fermenter

    Directory of Open Access Journals (Sweden)

    Krishnaiah, K.

    2005-01-01

    Full Text Available Various reactors such as tray, packed bed, rotating drum can be used for solid-state fermentation. In this paper the possibility of fluidized bed reactor as solid-state fermenter is considered. The design parameters, which affect the performances are identified and discussed. This information, in general can be used in the design and the development of an efficient fluidized bed solid-state fermenter. However, the objective here is to develop fluidized bed solid-state fermenter for palm kernel cake conversion into enriched animal and poultry feed.

  3. Dynamic crack propagation and arrest in orthotropic DCB fiber composite specimens. [Double Cantilever Beam

    Science.gov (United States)

    Williams, J. H., Jr.; Lee, S. S.; Kousiounelos, P. N.

    1981-01-01

    An orthotropic double cantilever beam (DCB) model is used to study dynamic crack propagation and arrest in 90 deg unidirectional Hercules AS/3501-6 graphite fiber epoxy composites. The dynamic fracture toughness of the composite is determined from tests performed on the long-strip specimen and DCB crack arrest experiments are conducted. By using the dynamic fracture toughness in a finite-difference solution of the DCB governing partial differential equations, a numerical solution of the crack propagation and arrest events is computed. Excellent agreement between the experimental and numerical crack arrest results are obtained.

  4. Experience with bretylium tosylate by a hospital cardiac arrest team.

    Science.gov (United States)

    Holder, D A; Sniderman, A D; Fraser, G; Fallen, E L

    1977-03-01

    The effect of bretylium tosylate (BT) was determined in 27 consecutive cases of resistant ventricular fibrillation (VF) encountered by a hospital cardiac arrest team. The VF was sustained and completely resistant to multiple injections of lidocaine, sequential DC shocks at 400 watt-sec and one or a combination of intravenous propranolol, diphenylhydantoin or procainamide. Following 30 min of sustained cardiac massage, BT (5 mg/kg i.v.) was administered. In 20 patients, VF was terminated within 9-12 min after DC shock. Eight of these patients failed to recover while 12 (44%) of all patients resuscitated survived to be discharged from hospital. Eleven out of 20 (55%) of all patients who had a cardiac arrest outside the CCU were survivors; only one out of seven in the CCU were successfully resuscitated. While receiving maintanance BT post-resuscitation (5 mg/kg i.m. q 8-12 hrs x 48 hrs), half the patients developed hypotension and three required vasopressors and/or fluid replacement. The data indicate that BT is a useful agent in patients with sustained VF refractory to repeated lidocaine injections, some other antiarrhythmic agents, and multiple DC shocks. PMID:837490

  5. Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

    Science.gov (United States)

    Rossetti, Andrea O.; van Rootselaar, Anne-Fleur; Wesenberg Kjaer, Troels; Horn, Janneke; Ullén, Susann; Friberg, Hans; Nielsen, Niklas; Rosén, Ingmar; Åneman, Anders; Erlinge, David; Gasche, Yvan; Hassager, Christian; Hovdenes, Jan; Kjaergaard, Jesper; Kuiper, Michael; Pellis, Tommaso; Stammet, Pascal; Wanscher, Michael; Wetterslev, Jørn; Wise, Matt P.; Cronberg, Tobias

    2016-01-01

    Objective: To identify reliable predictors of outcome in comatose patients after cardiac arrest using a single routine EEG and standardized interpretation according to the terminology proposed by the American Clinical Neurophysiology Society. Methods: In this cohort study, 4 EEG specialists, blinded to outcome, evaluated prospectively recorded EEGs in the Target Temperature Management trial (TTM trial) that randomized patients to 33°C vs 36°C. Routine EEG was performed in patients still comatose after rewarming. EEGs were classified into highly malignant (suppression, suppression with periodic discharges, burst-suppression), malignant (periodic or rhythmic patterns, pathological or nonreactive background), and benign EEG (absence of malignant features). Poor outcome was defined as best Cerebral Performance Category score 3–5 until 180 days. Results: Eight TTM sites randomized 202 patients. EEGs were recorded in 103 patients at a median 77 hours after cardiac arrest; 37% had a highly malignant EEG and all had a poor outcome (specificity 100%, sensitivity 50%). Any malignant EEG feature had a low specificity to predict poor prognosis (48%) but if 2 malignant EEG features were present specificity increased to 96% (p EEG was found in 1% of the patients with a poor outcome. Conclusions: Highly malignant EEG after rewarming reliably predicted poor outcome in half of patients without false predictions. An isolated finding of a single malignant feature did not predict poor outcome whereas a benign EEG was highly predictive of a good outcome. PMID:26865516

  6. Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.

    Science.gov (United States)

    Zhang, Liang; Trushin, Sergey; Christensen, Trace A; Bachmeier, Benjamin V; Gateno, Benjamin; Schroeder, Andreas; Yao, Jia; Itoh, Kie; Sesaki, Hiromi; Poon, Wayne W; Gylys, Karen H; Patterson, Emily R; Parisi, Joseph E; Diaz Brinton, Roberta; Salisbury, Jeffrey L; Trushina, Eugenia

    2016-01-01

    Altered brain metabolism is associated with progression of Alzheimer's Disease (AD). Mitochondria respond to bioenergetic changes by continuous fission and fusion. To account for three dimensional architecture of the brain tissue and organelles, we applied 3-dimensional electron microscopy (3D EM) reconstruction to visualize mitochondrial structure in the brain tissue from patients and mouse models of AD. We identified a previously unknown mitochondrial fission arrest phenotype that results in elongated interconnected organelles, "mitochondria-on-a-string" (MOAS). Our data suggest that MOAS formation may occur at the final stages of fission process and was not associated with altered translocation of activated dynamin related protein 1 (Drp1) to mitochondria but with reduced GTPase activity. Since MOAS formation was also observed in the brain tissue of wild-type mice in response to hypoxia or during chronological aging, fission arrest may represent fundamental compensatory adaptation to bioenergetic stress providing protection against mitophagy that may preserve residual mitochondrial function. The discovery of novel mitochondrial phenotype that occurs in the brain tissue in response to energetic stress accurately detected only using 3D EM reconstruction argues for a major role of mitochondrial dynamics in regulating neuronal survival. PMID:26729583

  7. Student perceptions of sudden cardiac arrest: a qualitative inquiry.

    Science.gov (United States)

    McDonough, Annette; Callan, Krista; Egizio, Katelyn; Kenney, Kaye; Gray, Gillian; Mundry, Gillian; Re, Gillian

    Sudden cardiac arrest (SCA) is the number one cause of death in young athletes in high school and university settings. Survival and outcomes of SCA is dependent on appropriate recognition of symptoms and immediate cardiopulmonary resuscitation (CPR), along with a shock from an automatic external defibrillator (AED). The three aims of the authors' study presented in this article were: to describe university students' perceptions and beliefs about sudden cardiac arrest, to describe university students' understanding of an AED and their level of preparedness to recognize and respond to a life threatening emergency event, and to identify university students' experiences of responding to handling life-threatening emergency events. Qualitative methodology was employed using semi-structured interviews and thematic analysis. Three major themes emerged from data analysis: confusion, uncertainty, and fear/uncomfortableness. These themes characterised participant's perceptions about SCA. The authors concluded that a lack of understanding of what SCA is and participants' inability to respond to an emergency event was evident. PMID:22585265

  8. An unusual cause of cardiac arrest in a hospitalized patient

    Directory of Open Access Journals (Sweden)

    K Ranjan Shetty

    2013-01-01

    Full Text Available We present an unusual case of 24 year old male who was hospitalized for dental procedure and developed cardiac arrest 2 days after the procedure. The patient presented with swelling of buccal cavity for which a biopsy was taken. Two days after the procedure, apparently normal patient suddenly presented at mid night with VT and VF, which were intractable requiring multiple DC shocks. During this period arterial blood gas analysis revealed severe acidosis. The circumstances led us to suspect poisoning as one of the cause for his medical condition. We looked for commonly available toxins. One of the commonly available toxins is hand sanitizer which contains Isopropyl alcohol, glycerin and perfume. Due to prolonged cardiac arrest and intractable arrhythmia patient had sustained hypoxic brain injury. Patient remained hemodynamically stable for next 9 days although his CNS status did not improve. Patient succumbed to sepsis on 9 th day. Healthcare professionals should be aware of such possibilities and treat the patients at the earliest and put a check on the easy availability of IPA based hand sanitizers.

  9. Variation in Out-of-Hospital Cardiac Arrest Management

    Directory of Open Access Journals (Sweden)

    Jason M. Jones

    2016-01-01

    Full Text Available Objective. To evaluate variation in airway management strategies in one suburban emergency medical services system treating patients experiencing out-of-hospital cardiac arrest (OHCA. Method. Retrospective chart review of all adult OHCA resuscitation during a 13-month period, specifically comparing airway management decisions. Results. Paramedics demonstrated considerable variation in their approaches to airway management. Approximately half of all OHCA patients received more than one airway management attempt (38/77 [49%], and one-quarter underwent three or more attempts (25/77 [25%]. One-third of patients arrived at the emergency department with a different airway device than initially selected (25/77 [32%]. Conclusion. This study confirmed our hypothesis that paramedics’ selection of ventilation strategies in cardiac arrest varies considerably. This observation raises concern because airway management diverts time and energy from interventions known to improve outcomes in OHCA management, such as cardiopulmonary resuscitation and defibrillation. More research is needed to identify more focused airway management strategies for prehospital care providers.

  10. Hemodynamics and vasopressor support in therapeutic hypothermia after cardiac arrest

    DEFF Research Database (Denmark)

    Bro-Jeppesen, John; Kjaergaard, Jesper; Søholm, Helle;

    2014-01-01

    AIM: Inducing therapeutic hypothermia (TH) in Out-of-Hospital Cardiac Arrest (OHCA) can be challenging due to its impact on central hemodynamics and vasopressors are frequently used to maintain adequate organ perfusion. The aim of this study was to assess the association between level of vasopres......AIM: Inducing therapeutic hypothermia (TH) in Out-of-Hospital Cardiac Arrest (OHCA) can be challenging due to its impact on central hemodynamics and vasopressors are frequently used to maintain adequate organ perfusion. The aim of this study was to assess the association between level......-score of Sequential Organ Failure Assessment (SOFA). The population was stratified by use of dopamine as first line intervention (D-group) or use of dopamine+norepinephrine/epinephrine (DA-group). Primary endpoint was 30-day mortality and secondary endpoint was in-hospital cause of death. RESULTS: Patients in the DA......-group carried a 49% all-cause 30-day mortality rate compared to 23% in the D-group, plog-rankCause of death...

  11. Non-equilibrium theory of arrested spinodal decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Olais-Govea, José Manuel; López-Flores, Leticia; Medina-Noyola, Magdaleno [Instituto de Física “Manuel Sandoval Vallarta,” Universidad Autónoma de San Luis Potosí, Álvaro Obregón 64, 78000 San Luis Potosí, SLP (Mexico)

    2015-11-07

    The non-equilibrium self-consistent generalized Langevin equation theory of irreversible relaxation [P. E. Ramŕez-González and M. Medina-Noyola, Phys. Rev. E 82, 061503 (2010); 82, 061504 (2010)] is applied to the description of the non-equilibrium processes involved in the spinodal decomposition of suddenly and deeply quenched simple liquids. For model liquids with hard-sphere plus attractive (Yukawa or square well) pair potential, the theory predicts that the spinodal curve, besides being the threshold of the thermodynamic stability of homogeneous states, is also the borderline between the regions of ergodic and non-ergodic homogeneous states. It also predicts that the high-density liquid-glass transition line, whose high-temperature limit corresponds to the well-known hard-sphere glass transition, at lower temperature intersects the spinodal curve and continues inside the spinodal region as a glass-glass transition line. Within the region bounded from below by this low-temperature glass-glass transition and from above by the spinodal dynamic arrest line, we can recognize two distinct domains with qualitatively different temperature dependence of various physical properties. We interpret these two domains as corresponding to full gas-liquid phase separation conditions and to the formation of physical gels by arrested spinodal decomposition. The resulting theoretical scenario is consistent with the corresponding experimental observations in a specific colloidal model system.

  12. Testing of long-flashover arresters designed for distribution lines

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Filho, Orsino; Mello, Darcy Ramalho de; Oliveira, Gloria Suzana Gomes de [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil)], Emails: orsino@cepel.br, darcy@cepel.br, gloria@cepel.br; Podporkin, Georgij; Wey, Acacio [Streamer Electric Company (Russian Federation)], E-mails: georgij.podporkin@streamer.ru, acacio.wey@bighost.com.br

    2007-07-01

    Outages of overhead power lines due to lightning strokes are one of the main causes of shortages of electric supplies and economic losses of power utilities. Pole-top metal oxide arresters can protect distribution lines against induced over-voltages, but they can be destroyed in case of direct lightning stroke. Long Flashover Arresters (LFAs) have been developed and used successfully for this purpose and have no possibility of being destroyed because the current flows externally along its surface. Since field experience with 10 kV LFAs has been very successful, it was decided to work on developing 13.8 kV LFAs, considering that it is the predominant voltage level of overhead distribution lines in Brazil and other countries. The performance of LFA for quenching and dielectric tests has been investigated through laboratory tests under conditions that typically represent electrical energy distribution systems. Details about these tests and their results are presented in this paper. Information about their design and applications are also shortly presented (author)

  13. Metabolic Resistance in Bed Bugs

    Directory of Open Access Journals (Sweden)

    Omprakash Mittapalli

    2011-03-01

    Full Text Available Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc. through gene mutations and increased metabolism. Bed bugs (Cimex lectularius are hematophagous ectoparasites that are poised to become one of the major pests in households throughout the United States. Currently, C. lectularius has attained a high global impact status due to its sudden and rampant resurgence. Resistance to pesticides is one factor implicated in this phenomenon. Although much emphasis has been placed on target sensitivity, little to no knowledge is available on the role of key metabolic players (e.g., cytochrome P450s and glutathione S-transferases towards pesticide resistance in C. lectularius. In this review, we discuss different modes of resistance (target sensitivity, penetration resistance, behavioral resistance, and metabolic resistance with more emphasis on metabolic resistance.

  14. Fluidized bed heat treating system

    Energy Technology Data Exchange (ETDEWEB)

    Ripley, Edward B; Pfennigwerth, Glenn L

    2014-05-06

    Systems for heat treating materials are presented. The systems typically involve a fluidized bed that contains granulated heat treating material. In some embodiments a fluid, such as an inert gas, is flowed through the granulated heat treating medium, which homogenizes the temperature of the heat treating medium. In some embodiments the fluid may be heated in a heating vessel and flowed into the process chamber where the fluid is then flowed through the granulated heat treating medium. In some embodiments the heat treating material may be liquid or granulated heat treating material and the heat treating material may be circulated through a heating vessel into a process chamber where the heat treating material contacts the material to be heat treated. Microwave energy may be used to provide the source of heat for heat treating systems.

  15. Particle pressures in fluidized beds. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, C.S.; Rahman, K.; Jin, C.

    1996-09-01

    This project studies the particle pressure, which may be thought of as the force exerted by the particulate phase of a multiphase mixture, independently of that exerted by other phases. The project is divided into two parts, one concerning gas and the other liquid fluidized beds. Previous work on gas fluidized beds had suggested that the particle pressures are generated by bubbling action. Thus, for these gas fluidized bed studies, the particle pressure is measured around single bubbles generated in 2-D fluidized beds, using special probes developed especially for this purpose. Liquid beds are immune from bubbling and the particle pressures proved too small to measure directly. However, the major interest in particle pressures in liquid beds lies in their stabilizing effect that arises from the effective elasticity (the derivative of the particle pressure with respect to the void fraction), they impart to the bed. So rather than directly measure the particle pressure, the authors inferred the values of the elasticity from measurements of instability growth in liquid beds; the inference was made by first developing a generic stability model (one with all the normally modeled coefficients left undetermined) and then working backwards to determine the unknown coefficients, including the elasticity.

  16. Effective Thermal Conductivity of Adsorbent Packed Beds

    Science.gov (United States)

    Mori, Hideo; Hamamoto, Yoshinori; Yoshida, Suguru

    The effective thermal conductivity of adsorbent packed beds of granular zeolite 13X and granular silica gel A in the presence of stagnant steam or air was measured under different conditions of the adsorbent bed temperature, particle size and filler-gas pressure. The measured effective thermal conductivity showed to become smaller with decreasing particle size or decreasing pressure, but it was nearly independent of the bed temperature. When steam was the filler-gas, the rise in the thermal conductivity of the adsorbent particles due to steam adsorption led to the increase in the effective thermal conductivity of the bed, and this effect was not negligible at high steam pressure for the bed of large particle size. It was found that both the predictions of the effective thermal conductivity by the Hayashi et al.'s model and the Bauer-Schlünder model generally agreed well with the measurements, by considering the particle thermal conductivity rise due to steam adsorption. The thermal conductivity of a consolidated bed of granular zeolite 13X was also measured, and it was found to be much larger than that of the packed bed especially at lower pressure. The above prediction models underestimated the effective thermal conductivity of the consolidated bed.

  17. Bed-levelling experiments with suspended load

    NARCIS (Netherlands)

    Talmon, A.M.; De Graaff, J.

    1991-01-01

    Bed-levelling experiments are conducted in a straight laboratory channel. The experiments involve a significant fraction of suspended sediment transport. The purpose of the experiments is to provide data for modelling of the direction of sediment transport on a transverse sloping alluvial river bed,

  18. Nonlinear dynamical characteristics of bed load motion

    Institute of Scientific and Technical Information of China (English)

    BAI Yuchuan; XU Haijue; XU Dong; Chiu-On Ng

    2006-01-01

    Bed forms of various kinds that evolve naturally on the bottom of sandy coasts and rivers are a result of the kinematics of bed load transport. Based on the group motion of particles in the bed load within the bottom layer, a study on the nonlinear dynamics of bed load transport is presented in this paper. It is found that some development stages, such as the initiation, the equilibrium sediment transport, and the transition from a smooth bed to sand dunes, can be accounted for by different states in the nonlinear system of the bed load transport. It is verified by comparison with experimental data reported by Laboratoire Nationae D'Hydraulique, Chatou, France, that the evolution from a smooth bed to sand dunes is determined by mutation in the bed load transport. This paper presents results that may offer theoretical explanations to the experimental observations. It is also an attempt to apply the state-of-the-art nonlinear science to the classical sediment transport mechanics.

  19. Particle Pressures in Fluidized Beds. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, C.S.; Rahman, K.; Jin, C.

    1996-09-01

    This project studies the particle pressure, which may be thought of as the force exerted by the particulate phase of a multiphase mixture, independently of that exerted by other phases. The project is divided into two parts, one concerning gas and the other liquid fluidized beds. Previous work on gas fluidized beds had suggested that the particle pressures are generated by bubbling action. Thus, for these gas fluidized bed studies, the particle pressure is measured around single bubbles generated in 2-D fluidized beds, using special probes developed especially for this purpose. Liquid beds are immune from bubbling and the particle pressures proved too small to measure directly. However, the major interest in particle pressures in liquid beds lies in their stabilizing effect that arises from the effective elasticity (the derivative of the particle pressure with respect to the void fraction): they impart to the bed. So rather than directly measure the particle pressure, we inferred the values of the elasticity from measurements of instability growth in liquid beds the inference was made by first developing a generic stability model (one with all the normally modeled coefficients left undetermined)and then working backwards to determine the unknown coefficients, including the elasticity.

  20. Container and Raised-Bed Gardening

    OpenAIRE

    Niemiera, Alexander Xavier, 1951-

    2009-01-01

    Raised beds, while requiring a high initial labor input, offer improved growing conditions and advantages compared to the existing soil. Improved plant growth, increased yields, and better accessibility are reasons to construct raised beds. This publication reviews the proper containers and plants, planting instructions, watering and potting soils, overwintering plants and more.

  1. Prevalence, Knowledge, and Concern About Bed Bugs.

    Science.gov (United States)

    Kaylor, Mary Beth; Wenning, Paul; Eddy, Christopher

    2015-01-01

    Recent research suggests that the resurgence of bed bugs in the U.S. has occurred at an alarming rate. Assumptions have been made that socioeconomic status is not associated with the prevalence of bed bug infestations. Little information is available at the local level, however, about the prevalence of bed bugs in private homes. The authors' pilot study aimed to identify prevalence, knowledge, and concern about bed bugs in one higher income village in Ohio utilizing survey methodology. Responses from 96 individuals who completed the Prevalence, Knowledge, and Concern About Bed Bugs survey were utilized for analysis. The majority of the sample respondents were white and 95% reported that they owned their residence. Only 6% knew someone with bed bugs. Additionally, 52% reported they were somewhat concerned about bed bugs. About 46% reported that they had changed their behavior. For a higher income area, the prevalence was dissimilar to the rate reported in the general public (about 20%). This suggests that bed bugs may be an environmental issue effecting low-income populations disproportionately. Further research is needed in areas of differing socioeconomic levels. PMID:26427264

  2. Determination of true bed thickness using folded bed model and borehole data

    Energy Technology Data Exchange (ETDEWEB)

    Xu, S.S.; Velasquillo-Martinez, L.G.; Grajales-Nishimura, J.M.; Murillo-Muneton, G. [Inst. Mexicano del Petroleo, Mexico City (Mexico); Garcia-Hernandez, J. [Petroleos Mexicanos Exploracion y Produccion, Tamaulipas (Mexico); Nieto-Samaniego, A.F. [Nacional Autonoma de Mexico Univ., Veracruz (Mexico). Centro de Geociencias

    2007-11-15

    The actual thickness of a given formation perpendicular to the bedding plane is known as the true bed thickness. Petroleum engineers rely on information regarding true bed thickness, particularly in dipping beds and in deviated holes because reservoir volume and isochore maps depend on these properties and not on the measured thickness. True bed thickness can be estimated from information gathered from well logs such as the dipmeter and borehole images. However, when deviations and dips exceed 10 degrees, corrections are needed. In this paper, a folded bed model was proposed to calculate the true bed thickness in the subsurface utilizing well log data. The value of true bed thickness (t) was shown to depend on the angle and the direction of the dip of the measured formation, as well as the drift angle and azimuth of the borehole. A case study from the Cantarell oil field in the southern Gulf of Mexico, offshore Campeche, was used to test the folded bed method. The model was shown to yield more uniform spatial change of the values of t, compared to the monoclinal bed model that often overestimates the average value of t. The maximum relative deviation of t from the monoclinal bed model reached 22.3 per cent and the maximum absolute deviation of t reached 34.5 m. The key factors that influence the values of t were found to be the bed dip, the dip difference between the top and base of the bed and the deviated angle of the well. The folded bed model yielded fewer changed values of the true bed thickness. 10 refs., 2 tabs., 9 figs.

  3. Peering inside the granular bed: illuminating feedbacks between bed-load transport and bed-structure evolution

    Science.gov (United States)

    Houssais, M.; Jerolmack, D. J.; Martin, R. L.

    2013-12-01

    The threshold of motion is perhaps the most important quantity to determine for understanding rates of bed load transport, however it is a moving target. Decades of research show that it changes in space and in time within a river, and is highly variable among different systems; however, these differences are not mechanistically understood. Recent researchers have proposed that the critical Shields stress is strongly dependent on the local configuration of the sediment bed [Frey and Church, 2011]. Critical Shields stress has been observed to change following sediment-transporting flood events in natural rivers [e.g., Turowski et al., 2011], while small-scale laboratory experiments have produced declining bed load transport rates associated with slow bed compaction [Charru et al., 2004]. However, no direct measurements have been made of the evolving bed structure under bed load transport, so the connection between granular controls and the threshold of motion remains uncertain. A perspective we adopt is that granular effects determine the critical Shields stress, while the fluid supplies a distribution of driving stresses. In order to isolate the granular effect, we undertake laminar bed load transport experiments using plastic beads sheared by a viscous oil in a small, annular flume. The fluid and beads are refractive index matched, and the fluid impregnated with a fluorescing powder. When illuminated with a planar laser sheet, we are able to image slices of the granular bed while also tracking the overlying sediment transport. We present the first results showing how bed load transport influences granular packing, and how changes in packing influence the threshold of motion to feed back on bed load transport rates. This effect may account for much of the variability observed in the threshold of motion in natural streams, and by extension offers a plausible explanation for hysteresis in bed load transport rates observed during floods. Charru, F., H. Mouilleron, and

  4. Sand attrition in conical spouted beds

    Institute of Scientific and Technical Information of China (English)

    Aranzazu R. Fernández-Akarregui; Jon Makibar; Isabel Alava; Luis Diaz; Fernando Cueva; Roberto Aguado; Gartzen Lopez; Martin Olazar

    2012-01-01

    A study was carried out on the attrition in conical spouted beds using two sands with different properties for several bed heights and gas flow rates.Furthermore,the influence of a draft tube was studied at ambient and high temperatures.The main objective was to acquire knowledge on the attrition of sand beds for biomass pyrolysis in a pilot plant provided with a conical spouted bed reactor.A first-order kinetic equation is proposed for sand attrition in a conical spouted bed at room temperature.The predicted attrition rate constant depends exponentially on excess air velocity over that for minimum spouting.Both the draft tube and temperature increase contribute to reduction of attrition.

  5. Incipient motion of gravel and coal beds

    Indian Academy of Sciences (India)

    Subhasish Dey; Uddaraju V Raju

    2002-10-01

    An experimental study on incipient motion of gravel and coal beds under unidirectional steady-uniform flow is presented. Experiments were carried out in a flume with various sizes of gravel and coal samples. The critical bed shear stresses for the experimental runs determined using side-wall correction show considerable disagreement with the standard curves. The characteristic parameters affecting the incipient motion of particles in rough-turbulent regime, identified based on physical reasoning and dimensional analysis, are the Shields parameter, particle Froude number, non-dimensional particle diameter and non-dimensional flow depth. Equations of critical bed shear stress for the initial movement of gravel and coal beds were obtained using experimental data. The method of application of critical bed shear stress equations is also mentioned.

  6. A Summary and Analysis of Warrantless Arrest Statutes for Domestic Violence in the United States

    Science.gov (United States)

    Zeoli, April M.; Norris, Alexis; Brenner, Hannah

    2011-01-01

    In the United States, all 50 states and the District of Columbia have enacted statutes that allow police officers to make warrantless arrests for domestic violence given probable cause; however, state laws differ from one another in multiple, important ways. Research on domestic violence warrantless arrest laws rarely describe them as anything…

  7. Mental Condition and Ventricular Size in Arrested Hydrocephalus: an Analysis of 29 Shunt‐independent Children

    NARCIS (Netherlands)

    HOLTZER, G.J.; de LANGE, S.A.; ORBAAN, I.J.C.; GELSEMA, R.

    1971-01-01

    textabstractMeasurement of the diameter of the ventricular system, in a series of 29 patients with arrested hydrocephalus who had become shunt‐independent, showed that enlargement of the ventricles does not necessarily play a part in the arrest of hydrocephalus, for in many of these cases the ventri

  8. Interfacial Crack Arrest in Sandwich Panels with Embedded Crack Stoppers Subjected to Fatigue Loading

    DEFF Research Database (Denmark)

    Martakos, G.; Andreasen, J. H.; Berggreen, Christian;

    2016-01-01

    A novel crack arresting device has been implemented in sandwich panels and tested using a special rig to apply out-of-plane loading on the sandwich panel face-sheets. Fatigue crack propagation was induced in the face-core interface of the sandwich panels which met the crack arrester. The effect...

  9. Program Completion and Re-Arrest in a Batterer Intervention System

    Science.gov (United States)

    Bennett, Larry W.; Stoops, Charles; Call, Christine; Flett, Heather

    2007-01-01

    Objective: The authors examine the effects of batterer intervention program (BIP) completion on domestic violence re-arrest in an urban system of 30 BIPs with a common set of state standards, common program completion criteria, and centralized criminal justice supervision. Method: 899 men arrested for domestic violence were assessed and completed…

  10. 38 CFR 3.375 - Determination of inactivity (complete arrest) in tuberculosis.

    Science.gov (United States)

    2010-07-01

    ... inactivity (complete arrest) in tuberculosis. 3.375 Section 3.375 Pensions, Bonuses, and Veterans' Relief...) in tuberculosis. (a) Pulmonary tuberculosis. A veteran shown to have had pulmonary tuberculosis will...) Nonpulmonary disease. Determination of complete arrest of nonpulmonary tuberculosis requires absence...

  11. Recent Trends of Technology of Zinc-Oxide Surge Arrester for Electric Power System

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.S.; Kim, K.U.; Cho, H.G. [Korea Electrotechnology Research Institute (Korea); Park, T.G. [Changwon National University (Korea); Park, S.H. [KEPCO (Korea)

    1999-05-01

    Metal-oxide surge arresters were developed in the late 1970s, and were immediately recognized as significant breakthrough in over-voltage protection of power system. Work was continued throughout the world on the design, development and application of metal-oxide surge arresters. (author). 6 refs., 1 fig., 6 tabs.

  12. Gender Differences in Drug Use, Sexually Transmitted Diseases, and Risky Sexual Behavior among Arrested Youths

    Science.gov (United States)

    Dembo, Richard; Belenko, Steven; Childs, Kristina; Greenbaum, Paul E.; Wareham, Jennifer

    2010-01-01

    Data was collected on arrested youths processed at a centralized intake facility, including youths released back to the community and those placed in secure detention. This article reports the results of a test of a structural model involving newly arrested male and female youths' sexually transmitted diseases (STD) test results, urine analysis…

  13. Same-Sex and Race-Based Disparities in Statutory Rape Arrests.

    Science.gov (United States)

    Chaffin, Mark; Chenoweth, Stephanie; Letourneau, Elizabeth J

    2016-01-01

    This study tests a liberation hypothesis for statutory rape incidents, specifically that there may be same-sex and race/ethnicity arrest disparities among statutory rape incidents and that these will be greater among statutory rape than among forcible sex crime incidents. 26,726 reported incidents of statutory rape as defined under state statutes and 96,474 forcible sex crime incidents were extracted from National Incident-Based Reporting System data sets. Arrest outcomes were tested using multilevel modeling. Same-sex statutory rape pairings were rare but had much higher arrest odds. A victim-offender romantic relationship amplified arrest odds for same-sex pairings, but damped arrest odds for male-on-female pairings. Same-sex disparities were larger among statutory than among forcible incidents. Female-on-male incidents had uniformly lower arrest odds. Race/ethnicity effects were smaller than gender effects and more complexly patterned. The findings support the liberation hypothesis for same-sex statutory rape arrest disparities, particularly among same-sex romantic pairings. Support for race/ethnicity-based arrest disparities was limited and mixed. PMID:25416040

  14. Return to Work in Out-of-Hospital Cardiac Arrest Survivors

    DEFF Research Database (Denmark)

    Kragholm, Kristian; Wissenberg, Mads; Mortensen, Rikke Normark;

    2015-01-01

    BACKGROUND: Data on long-term function of out-of-hospital cardiac arrest survivors are sparse. We examined return to work as a proxy of preserved function without major neurologic deficits in survivors. METHODS AND RESULTS: In Denmark, out-of-hospital cardiac arrests have been systematically repo...

  15. Programmed cell cycle arrest is required for infection of corn plants by the fungus Ustilago maydis.

    Science.gov (United States)

    Castanheira, Sónia; Mielnichuk, Natalia; Pérez-Martín, José

    2014-12-01

    Ustilago maydis is a plant pathogen that requires a specific structure called infective filament to penetrate the plant tissue. Although able to grow, this filament is cell cycle arrested on the plant surface. This cell cycle arrest is released once the filament penetrates the plant tissue. The reasons and mechanisms for this cell cycle arrest are unknown. Here, we have tried to address these questions. We reached three conclusions from our studies. First, the observed cell cycle arrest is the result of the cooperation of at least two distinct mechanisms: one involving the activation of the DNA damage response (DDR) cascade; and the other relying on the transcriptional downregulation of Hsl1, a kinase that modulates the G2/M transition. Second, a sustained cell cycle arrest during the infective filament step is necessary for the virulence in U. maydis, as a strain unable to arrest the cell cycle was severely impaired in its ability to infect corn plants. Third, production of the appressorium, a structure required for plant penetration, is incompatible with an active cell cycle. The inability to infect plants by strains defective in cell cycle arrest seems to be caused by their failure to induce the appressorium formation process. In summary, our findings uncover genetic circuits to arrest the cell cycle during the growth of this fungus on the plant surface, thus allowing the penetration into plant tissue.

  16. Complement activation and its prognostic role in post-cardiac arrest patients

    DEFF Research Database (Denmark)

    Jenei, Z M; Zima, E; Csuka, D;

    2014-01-01

    of therapeutic hypothermia predicted 30-day mortality regardless of age, sex and the APACHE II score. Complement activation occurs in post-cardiac arrest patients, and its extent correlates with 30-day survival. The C3a/C3 ratio might prove useful for estimating the prognosis of comatose post-cardiac arrest...

  17. 46 CFR 32.20-10 - Flame arresters-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Flame arresters-TB/ALL. 32.20-10 Section 32.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Equipment Installations § 32.20-10 Flame arresters—TB/ALL. Flame arresters must be of a type...

  18. 46 CFR 30.10-63 - Spark arrester-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Spark arrester-TB/ALL. 30.10-63 Section 30.10-63 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-63 Spark arrester—TB/ALL. The term spark arrester means any device, assembly, or method of...

  19. Temporal Differences in Out-of-Hospital Cardiac Arrest Incidence and Survival

    DEFF Research Database (Denmark)

    Bagai, Akshay; McNally, Bryan F; Al-Khatib, Sana M;

    2013-01-01

    Understanding temporal differences in the incidence and outcomes of out-of-hospital cardiac arrest (OHCA) has important implications for developing preventative strategies and optimizing systems for OHCA care.......Understanding temporal differences in the incidence and outcomes of out-of-hospital cardiac arrest (OHCA) has important implications for developing preventative strategies and optimizing systems for OHCA care....

  20. 46 CFR 30.10-23 - Flame arrester-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Flame arrester-TB/ALL. 30.10-23 Section 30.10-23 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-23 Flame arrester—TB/ALL. The term flame arrester means any device or assembly of a cellular,...

  1. Innovative Bed Load Measurement System for Large Alpine Gravel-Bed Rivers

    Science.gov (United States)

    Seitz, H.; Habersack, H. M.

    2009-04-01

    The aim of the work is to figure out the bed load transport processes using direct and surrogate measurement methods for the free flowing reach of the Drau River and its most important tributary Isel River, both large Alpine gravel-bed rivers, situated in the south western part of Austria. There are some techniques for bed load measurements in natural streams; we used collecting moving particles and indirectly determining transport intensity at the study sites. Former measurements in the study reach were performed also using mobile bed load samplers and fixed bed load samplers. Individually they all are adequate bed load measurement instruments - used in combination they are complementing one another, whereas each applied separately leads to specific deficits. The investigation payed special attention on results out of the geophone installations, whereas steel plate vibrations (the plates are mounted on top of concrete structures even with the river bed surface) caused by bed load particles with a diameter larger than about 20 mm are inducing a signal into the geophones. The signal above a defined threshold voltage than is recorded in a computer system as the sum of impacts during one minute intervals. The spatio-temporal distribution of the transported bed load material, its amount and the transport processes itself could be figured out for the first time out of continuous data collection since 2006 for large alpine gravel-bed rivers. Before building up the gauging stations there were no continuous recordings of bed load transport processes in large alpine rivers over their entire cross section, hence the investigation promises a better process understanding and the possibility to determine bed load transport rates and a rough approximation of the grain size distributions of the transported bed load material under different flow conditions. A relation between detected geophone records, the flow discharge and direct bed load sampling methods (Large Helley Smith

  2. Dynamical Arrest, Structural Disorder, and Optimization of Organic Photovoltaic Devices

    Energy Technology Data Exchange (ETDEWEB)

    Gould, Ian; Dmitry, Matyushov

    2014-09-11

    This project describes fundamental experimental and theoretical work that relates to charge separation and migration in the solid, heterogeneous or aggregated state. Marcus theory assumes a system in equilibrium with all possible solvent (dipolar) configurations, with rapid interconversion among these on the ET timescale. This project has addressed the more general situation where the medium is at least partially frozen on the ET timescale, i.e. under conditions of dynamical arrest. The approach combined theory and experiment and includes: (1) Computer simulations of model systems, (2) Development of analytical procedures consistent with computer experiment and (3) Experimental studies and testing of the formal theories on this data. Electron transfer processes are unique as a consequence of the close connection between kinetics, spectroscopy and theory, which is an essential component of this work.

  3. First permanent molar root development arrest associated with compound odontoma.

    Science.gov (United States)

    Gunda, Sachin A; Patil, Anil; Varekar, Aniruddha

    2013-07-04

    Trauma or infection to the primary tooth may have deleterious effects on the underlying developing tooth buds. Anatomically the root apices of primary teeth are in close proximity to the developing permanent tooth buds; hence spread of infection originating from pulp necrosis of primary tooth may not only affect the underlying tooth bud but may also affect the adjacent tooth buds. The extent of malformation depends on the developmental stage of tooth or the age of patient. Presented here is a rare case of complete arrest of maxillary first permanent molar root growth due to spread of periapical infection originating from second primary molar leading to failure of its eruption and finally extraction. Histopathlogical analysis revealed compound odontoma associated with maxillary first permanent molar.

  4. Anaphylactic shock and cardiac arrest caused by thiamine infusion.

    Science.gov (United States)

    Juel, Jacob; Pareek, Manan; Langfrits, Christian Sigvald; Jensen, Svend Eggert

    2013-01-01

    Parenteral thiamine has a very high safety profile. The most common adverse effect is local irritation; however, anaphylactic or anaphylactoid reactions may occur, mostly related to intravenous administration. We describe a 44-year-old man, a chronic alcoholic, who was admitted with alcohol intoxication and developed cardiac arrest due to anaphylactic shock following intravenous thiamine infusion. The patient was successfully resuscitated after 15 min and repeated epinephrine administrations. He was discharged in good health after 14 days. This case report emphasises both the importance of recognising the symptoms of anaphylaxis and the fact that facilities for treating anaphylaxis and cardiopulmonary resuscitation should be available when thiamine or for that matter, any drug is given in-hospital. PMID:23853017

  5. Cardiopulmonary arrest induced by anaphylactoid reaction with contrast media.

    Science.gov (United States)

    Nakamura, Iwao; Hori, Shingo; Funabiki, Tomohiro; Sekine, Kazuhiko; Kimura, Hiroyuki; Fujishima, Seitaro; Aoki, Katsunori; Kuribayashi, Sachio; Aikawa, Naoki

    2002-05-01

    Anaphylactoid reactions to iodinated contrast media can cause life-threatening events and even death. A 44-year-old woman presented with cardiopulmonary arrest (CPA) immediately following the administration of nonionic iodinated contrast media for an intravenous pyelography. Her cardiac rhythm during CPA was asystole. She was successfully resuscitated by the radiologists supported by paged emergency physicians using the prompt intravenous administration of 1 mg of epinephrine. Neither laryngeal edema nor bronchial spasm was observed during the course of treatment, and she was discharged on the 4th day without any complications. The patient did not have a history of allergy, but had experienced a myocardial infarction and aortitis. She had undergone 11 angiographies and had been taking a beta-adrenergic receptor antagonist. Planned emergency medical backup is advisable to ensure resuscitation in the event of an anaphylactoid reaction to the use of contrast media in-hospital settings. PMID:12009227

  6. Opiate Withdrawal Complicated by Tetany and Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Irfanali R. Kugasia

    2014-01-01

    Full Text Available Patients with symptoms of opiate withdrawal, after the administration of opiate antagonist by paramedics, are a common presentation in the emergency department of hospitals. Though most of opiate withdrawal symptoms are benign, rarely they can become life threatening. This case highlights how a benign opiate withdrawal symptom of hyperventilation led to severe respiratory alkalosis that degenerated into tetany and cardiac arrest. Though this patient was successfully resuscitated, it is imperative that severe withdrawal symptoms are timely identified and immediate steps are taken to prevent catastrophes. An easier way to reverse the severe opiate withdrawal symptom would be with either low dose methadone or partial opiate agonists like buprenorphine. However, if severe acid-base disorder is identified, it would be safer to electively intubate these patients for better control of their respiratory and acid-base status.

  7. Deep hypothermic circulatory arrest: real-life suspended animation.

    Science.gov (United States)

    Chau, Katherine H; Ziganshin, Bulat A; Elefteriades, John A

    2013-01-01

    Deep hypothermic circulatory arrest (DHCA) is a cerebral protection technique that was developed in the 1950s and popularized in the 1970s. It has become one of the three most common cerebral protection techniques currently used in aortic arch surgeries, with the other two being antegrade cerebral perfusion (ACP) and retrograde cerebral perfusion (RCP). At our institution, DHCA has been the cerebral protection technique of choice for over a quarter century. Our clinical experience with DHCA has been very positive, and our clinical studies have shown DHCA to have outcomes equal to (and sometimes better than) those of ACP and RCP, and DHCA to be very effective at preserving neurocognitive function. Other institutions, however, prefer ACP or RCP to DHCA. Each technique has its own set of pros and cons, and the question regarding which technique is the superior method for cerebral protection is hotly debated.

  8. A Unique Case of Cardiac Arrest following K2 Abuse

    Directory of Open Access Journals (Sweden)

    Saif Ibrahim

    2014-01-01

    Full Text Available Sudden cardiac death (SCD accounts for up to 450,000 deaths every year in the United States (Zipes et al. (2006. Most cases of sudden cardiac death occur in subjects with no prior history of heart disease (Myerburg et al. (1998. The incidence of sudden death in a general population has been shown to increase contemporaneously with substance abuse (Phillips et al. (1999. The causative association of sudden death with cocaine, methadone, and volatile agents is well established (Adgey et al. (1995 and Isner et al. (1986. We describe a case of out-of-hospital cardiac arrest temporally related to abuse of the synthetic cannabinoid street drug known as K2. To our knowledge, there are no previously documented cases of sudden cardiac death associated with synthetic cannabinoids although they have been linked to myocardial infarction in teenagers despite normal coronary angiography (Mir et al. (2011.

  9. Arrest as a General Property of the Supercooled Liquid State.

    Science.gov (United States)

    Sluyters, Jan H; Sluyters-Rehbach, Margaretha

    2016-04-21

    Owing to the universal presence of intermolecular interactions, it has to be expected that at some well-defined lower temperature a liquid loses its dynamic properties like fluidity and self-diffusion. As a sequel to two earlier papers on the discovery of such an arrest temperature T0 for supercooled water at 243 K, where also the coexisting vapor pressure was found to become zero, in this paper a further study is undertaken of the behavior of a selection of other liquids. At first, two simple equations of state (van der Waals and virial) are shown in principle to predict a zero vapor pressure at a finite temperature. The interaction parameters B (second virial coefficient) and μJT (Joule-Thomson coefficient) of the vapor are found to become virtually infinite at a temperature T0,B, with a value equal or close to the T0 derived from the liquid properties. Just as earlier found for water, the latter is obtained by extrapolation of several available dynamic and equilibrium data, which should produce an intersection with the temperature axis at the same T0 value. With the exception of molten salts and liquid pure metals, this condition appears to be fulfilled quite accurately. Thus, the temperature of arrest is a general phenomenon for supercooled liquids. As an illustration, it is shown how the PVT diagram of carbon dioxide can be extended into the supercooled temperature region. It is argued that T0 is the temperature below which the Boltzmann energy, kT, is lower than the minimal energy needed for a molecule to break the interactions with its surrounding molecules. We propose to name this minimal energy, kT0, the multimolecular potential of the liquid object. The relationship of the liquid multimolecular potential with the pair potential, ε, of the molecular species is established for various examples and appears to be a proportionality with ε ≈ 2kT0. PMID:27070201

  10. Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

    Science.gov (United States)

    Rossetti, Andrea O.; van Rootselaar, Anne-Fleur; Wesenberg Kjaer, Troels; Horn, Janneke; Ullén, Susann; Friberg, Hans; Nielsen, Niklas; Rosén, Ingmar; Åneman, Anders; Erlinge, David; Gasche, Yvan; Hassager, Christian; Hovdenes, Jan; Kjaergaard, Jesper; Kuiper, Michael; Pellis, Tommaso; Stammet, Pascal; Wanscher, Michael; Wetterslev, Jørn; Wise, Matt P.; Cronberg, Tobias

    2016-01-01

    Objective: To identify reliable predictors of outcome in comatose patients after cardiac arrest using a single routine EEG and standardized interpretation according to the terminology proposed by the American Clinical Neurophysiology Society. Methods: In this cohort study, 4 EEG specialists, blinded to outcome, evaluated prospectively recorded EEGs in the Target Temperature Management trial (TTM trial) that randomized patients to 33°C vs 36°C. Routine EEG was performed in patients still comatose after rewarming. EEGs were classified into highly malignant (suppression, suppression with periodic discharges, burst-suppression), malignant (periodic or rhythmic patterns, pathological or nonreactive background), and benign EEG (absence of malignant features). Poor outcome was defined as best Cerebral Performance Category score 3–5 until 180 days. Results: Eight TTM sites randomized 202 patients. EEGs were recorded in 103 patients at a median 77 hours after cardiac arrest; 37% had a highly malignant EEG and all had a poor outcome (specificity 100%, sensitivity 50%). Any malignant EEG feature had a low specificity to predict poor prognosis (48%) but if 2 malignant EEG features were present specificity increased to 96% (p < 0.001). Specificity and sensitivity were not significantly affected by targeted temperature or sedation. A benign EEG was found in 1% of the patients with a poor outcome. Conclusions: Highly malignant EEG after rewarming reliably predicted poor outcome in half of patients without false predictions. An isolated finding of a single malignant feature did not predict poor outcome whereas a benign EEG was highly predictive of a good outcome. PMID:26865516

  11. Development of an Electro–Thermal Model for ZnO Surge Arrester Under Contamination

    Directory of Open Access Journals (Sweden)

    E. Melgoza–Vázquez

    2010-01-01

    Full Text Available An electro–thermal model for a Zinc Oxide (ZnO surge arrester under contamination tests is presented. The model is based in three sub–models: electrical, thermal and contamination, which interact in order to obtain the surge arrester performance under contamination tests. The electrical model is obtained from measurements and is based on a capacitance and a non–linear resistor. The thermal model takes into account the heat generated and dissipated by the column of varistors and its surroundings. The contamination is represented by a dynamic impedance obtained from measurements in the arrester column during contamination tests. The full model is validated by calculating the temperature increase during contamination tests carried out in a two units ZnO surge arrester, class 190 kV. Finally, the results of the effect of several design and construction parameters in the voltage and temperature distribution in the arrester columns during contamination tests are presented.

  12. Near death experiences, cognitive function and psychological outcomes of surviving cardiac arrest.

    Science.gov (United States)

    Parnia, S; Spearpoint, K; Fenwick, P B

    2007-08-01

    Cardiac arrest is associated with a number of cognitive processes as well as long term psychological outcomes. Recent studies have indicated that approximately 10-20% of cardiac arrest survivors report cognitive processes, including the ability to recall specific details of their resuscitation from the period of cardiac arrest. In addition it has been demonstrated that these cognitive processes are consistent with the previously described near death experience and that those who have these experiences are left with long term positive life enhancing effects. There have also been numerous studies that have indicated that although the quality of life for cardiac arrest survivors is generally good, some are left with long term cognitive impairments as well as psychological sequelae such as post-traumatic stress disorder. This paper will review near death experiences, cognitive function and psychological outcomes in survivors of cardiac arrest.

  13. Application of Powell's optimization method to surge arrester circuit models' parameters

    Energy Technology Data Exchange (ETDEWEB)

    Christodoulou, C.A.; Stathopulos, I.A. [National Technical University of Athens, School of Electrical and Computer Engineering, 9 Iroon Politechniou St., Zografou Campus, 157 80 Athens (Greece); Vita, V.; Ekonomou, L.; Chatzarakis, G.E. [A.S.PE.T.E. - School of Pedagogical and Technological Education, Department of Electrical Engineering Educators, N. Heraklion, 141 21 Athens (Greece)

    2010-08-15

    Powell's optimization method has been used for the evaluation of the surge arrester models parameters. The proper modelling of metal-oxide surge arresters and the right selection of equivalent circuit parameters are very significant issues, since quality and reliability of lightning performance studies can be improved with the more efficient representation of the arresters' dynamic behavior. The proposed approach selects optimum arrester model equivalent circuit parameter values, minimizing the error between the simulated peak residual voltage value and this given by the manufacturer. Application of the method in performed on a 120 kV metal oxide arrester. The use of the obtained optimum parameter values reduces significantly the relative error between the simulated and manufacturer's peak residual voltage value, presenting the effectiveness of the method. (author)

  14. Arrest functions of the MIF ligand/receptor axes in atherogenesis

    Directory of Open Access Journals (Sweden)

    Sabine eTillmann

    2013-05-01

    Full Text Available Macrophage migration inhibitory factor (MIF has been defined as an important chemokine-like function (CLF chemokine with an essential role in monocyte recruitment and arrest. Adhesion of monocytes to the vessel wall and their transendothelial migration are critical in atherogenesis and many other inflammatory diseases. Chemokines carefully control all steps of the monocyte recruitment process. Those chemokines specialized in controlling arrest are typically immobilized on the endothelial surface, mediating the arrest of rolling monocytes by chemokine receptor-triggered pathways. The chemokine receptor CXCR2 functions as an important arrest receptor on monocytes. An arrest function has been revealed for the bona fide CXCR2 ligands CXCL1 and CXCL8, but genetic studies also suggested that additional arrest chemokines are likely to be involved in atherogenic leukocyte recruitment. While CXCR2 is known to interact with numerous CXC chemokine ligands, the CLF-chemokine MIF, which structurally does not belong to the CXC chemokine sub-family, was surprisingly identified as a non-cognate ligand of CXCR2, responsible for critical arrest functions during the atherogenic process. MIF was originally identified as macrophage migration inhibitory factor, but is now known as a potent inflammatory cytokine with chemokine-like functions including chemotaxis and leukocyte arrest. This review will cover the mechanisms underlying these functions, including MIF’s effects on LFA1 integrin activity and signal transduction, and will discuss the structural similarities between MIF and the bona fide CXCR2 ligand CXCL8 while emphasizing the structural differences. As MIF also interacts with CXCR4, a chemokine receptor implicated in CXCL12-elicited lymphocyte arrest, the arrest potential of the MIF/CXCR4 axis will also be scrutinized as well as the recently identified role of pericyte MIF in attracting leukocytes exiting through venules as part of the pericyte 'motility

  15. Cardiac arrest during gamete release in chum salmon regulated by the parasympathetic nerve system.

    Directory of Open Access Journals (Sweden)

    Yuya Makiguchi

    Full Text Available Cardiac arrest caused by startling stimuli, such as visual and vibration stimuli, has been reported in some animals and could be considered as an extraordinary case of bradycardia and defined as reversible missed heart beats. Variability of the heart rate is established as a balance between an autonomic system, namely cholinergic vagus inhibition, and excitatory adrenergic stimulation of neural and hormonal action in teleost. However, the cardiac arrest and its regulating nervous mechanism remain poorly understood. We show, by using electrocardiogram (ECG data loggers, that cardiac arrest occurs in chum salmon (Oncorhynchus keta at the moment of gamete release for 7.39+/-1.61 s in females and for 5.20+/-0.97 s in males. The increase in heart rate during spawning behavior relative to the background rate during the resting period suggests that cardiac arrest is a characteristic physiological phenomenon of the extraordinarily high heart rate during spawning behavior. The ECG morphological analysis showed a peaked and tall T-wave adjacent to the cardiac arrest, indicating an increase in potassium permeability in cardiac muscle cells, which would function to retard the cardiac action potential. Pharmacological studies showed that the cardiac arrest was abolished by injection of atropine, a muscarinic receptor antagonist, revealing that the cardiac arrest is a reflex response of the parasympathetic nerve system, although injection of sotalol, a beta-adrenergic antagonist, did not affect the cardiac arrest. We conclude that cardiac arrest during gamete release in spawning release in spawning chum salmon is a physiological reflex response controlled by the parasympathetic nervous system. This cardiac arrest represents a response to the gaping behavior that occurs at the moment of gamete release.

  16. Condensation in Nanoporous Packed Beds.

    Science.gov (United States)

    Ally, Javed; Molla, Shahnawaz; Mostowfi, Farshid

    2016-05-10

    In materials with tiny, nanometer-scale pores, liquid condensation is shifted from the bulk saturation pressure observed at larger scales. This effect is called capillary condensation and can block pores, which has major consequences in hydrocarbon production, as well as in fuel cells, catalysis, and powder adhesion. In this study, high pressure nanofluidic condensation studies are performed using propane and carbon dioxide in a colloidal crystal packed bed. Direct visualization allows the extent of condensation to be observed, as well as inference of the pore geometry from Bragg diffraction. We show experimentally that capillary condensation depends on pore geometry and wettability because these factors determine the shape of the menisci that coalesce when pore filling occurs, contrary to the typical assumption that all pore structures can be modeled as cylindrical and perfectly wetting. We also observe capillary condensation at higher pressures than has been done previously, which is important because many applications involving this phenomenon occur well above atmospheric pressure, and there is little, if any, experimental validation of capillary condensation at such pressures, particularly with direct visualization. PMID:27115446

  17. CERTS Microgrid Laboratory Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Lasseter, R. H.; Eto, J. H.; Schenkman, B.; Stevens, J.; Volkmmer, H.; Klapp, D.; Linton, E.; Hurtado, H.; Roy, J.

    2010-06-08

    CERTS Microgrid concept captures the emerging potential of distributed generation using a system approach. CERTS views generation and associated loads as a subsystem or a 'microgrid'. The sources can operate in parallel to the grid or can operate in island, providing UPS services. The system can disconnect from the utility during large events (i.e. faults, voltage collapses), but may also intentionally disconnect when the quality of power from the grid falls below certain standards. CERTS Microgrid concepts were demonstrated at a full-scale test bed built near Columbus, Ohio and operated by American Electric Power. The testing fully confirmed earlier research that had been conducted initially through analytical simulations, then through laboratory emulations, and finally through factory acceptance testing of individual microgrid components. The islanding and resynchronization method met all Institute of Electrical and Electronics Engineers Standard 1547 and power quality requirements. The electrical protection system was able to distinguish between normal and faulted operation. The controls were found to be robust under all conditions, including difficult motor starts and high impedance faults.

  18. Heat and Mass Transfer Enforcement of Vibrating Fluidized Bed

    Institute of Scientific and Technical Information of China (English)

    ChuZhide; YangJunhong; 等

    1994-01-01

    This paper briefly introduces the development of vibrating fluidized bed at home and abroad,elaborates the vibration properties of vibrating fluidized bed.the fluidizing velocity and pressure drop of the bed layer,it also deduces the non-steady state drying dynamic equations of vibrating fluidized bed,analyzes main factors which influence the drying rate and inquires into drying rules of fixed bed and vibrating fluidized bed.

  19. A PROTOTYPE FOUR INCH SHORT HYDRIDE (FISH) BED AS A REPLACEMENT TRITIUM STORAGE BED

    Energy Technology Data Exchange (ETDEWEB)

    Klein, J.; Estochen, E.; Shanahan, K.; Heung, L.

    2011-02-23

    The Savannah River Site (SRS) tritium facilities have used 1st generation (Gen1) metal hydride storage bed assemblies with process vessels (PVs) fabricated from 3 inch nominal pipe size (NPS) pipe to hold up to 12.6 kg of LaNi{sub 4.25}Al{sub 0.75} metal hydride for tritium gas absorption, storage, and desorption for over 15 years. The 2nd generation (Gen2) of the bed design used the same NPS for the PV, but the added internal components produced a bed nominally 1.2 m long, and presented a significant challenge for heater cartridge replacement in a footprint limited glove-box. A prototype 3rd generation (Gen3) metal hydride storage bed has been designed and fabricated as a replacement candidate for the Gen2 storage bed. The prototype Gen3 bed uses a PV pipe diameter of 4 inch NPS so the bed length can be reduced below 0.7 m to facilitate heater cartridge replacement. For the Gen3 prototype bed, modeling results show increased absorption rates when using hydrides with lower absorption pressures. To improve absorption performance compared to the Gen2 beds, a LaNi{sub 4.15}Al{sub 0.85} material was procured and processed to obtain the desired pressure-composition-temperature (PCT) properties. Other bed design improvements are also presented.

  20. Modelling the bed characteristics in fluidised-beds for top-spray coating processes

    Institute of Scientific and Technical Information of China (English)

    Mike Vanderroost; Frederik Ronsse; Koen Dewettinck; Jan G.Pieters

    2012-01-01

    A particle sub-model describing the bed characteristics of a bubbling fluidised bed is presented.Atomisation air,applied at high pressures via a nozzle positioned above the bed for s pray formation,is incorporated in the model since its presence has a profound influence on the bed characteristics,though the spray itself is not yet considered.A particle sub-model is developed using well-known empirical relations for particle drag force,bubble growth and velocity and particle distribution above the fluidised-bed surface.Simple but effective assumptions and abstractions were made concerning bubble distribution,particle ejection at the bed surface and the behaviour of atomisation air flow upon impacting the surface of a bubbling fluidised bed.The model was shown to be capable of predicting the fluidised bed characteristics in terms of bed heights,voidage distributions and solids volume fractions with good accuracy in less than 5 min of calculation time on a regular desktop PC.It is therefore suitable for incorporation into general process control models aimed at dynamic control for process efficiency and product quality in top-spray fluidised bed coating processes.

  1. Modelling of Devolatilization in Fluidized Bed Combustion

    DEFF Research Database (Denmark)

    Stenseng, Mette; Lin, Weigang; Johnsson, Jan Erik;

    1997-01-01

    A mathematical model is developed to describe the devolatilization process in a circulating fluidized bed combustor. The model is a combination of two submodels: single particle devolatilization and fluid dynamics. The single particle model includes the influence of both chemical kinetics and heat...... of CSTR's and the size and number of CSTR's has been estimated from tracer experiments in an 80 MWth CFB boiler. It was not possible to evaluate the model against experimental data, but the dependence of particle size on the degree of devolatilization in the dense bed agrees qualitative with the expected...... behavior. The model shows that the devolatilization mainly occurs in the dense bed....

  2. Fluidised-bed combustion of gasification residue

    Energy Technology Data Exchange (ETDEWEB)

    Korpela, T.; Kudjoi, A.; Hippinen, I.; Heinolainen, A.; Suominen, M.; Lu Yong [Helsinki Univ. of Technology (Finland). Lab of Energy Economics and Power Plant Engineering

    1996-12-01

    Partial gasification processes have been presented as possibilities for future power production. In the processes, the solid materials removed from a gasifier (i.e. fly ash and bed material) contain unburnt fuel and the fuel conversion is increased by burning this gasification residue either in an atmospheric or a pressurised fluidised-bed. In this project, which is a part of European JOULE 2 EXTENSION research programme, the main research objectives are the behaviour of calcium and sulphur compounds in solids and the emissions of sulphur dioxide and nitrogen oxides (NO{sub x} and N{sub 2}O) in pressurised fluidised-bed combustion of gasification residues. (author)

  3. Bed bug outbreak in a neonatal unit.

    Science.gov (United States)

    Bandyopadhyay, T; Kumar, A; Saili, A

    2015-10-01

    There has been a worldwide increase in bed bug infestations over the last 10-15 years. A major stigma is placed upon the institutions found to be infested. We report our experience with an outbreak of the tropical bed bug, Cimex hemipterus, in a neonatal unit. The outbreak not only affected the admitted newborns and mothers by causing a wide variety of rashes and inducing sleeplessness, but also impinged upon the health professionals and their families by producing similar symptomology. It is important for healthcare providers to be aware of, and for each healthcare facility to have, bed bug prevention and control policies. PMID:25591490

  4. Arrest Decisions as Precludes To? An Evaluation of Policy Related Research. Volume I: Administrative Summary and Training Script.

    Science.gov (United States)

    Neithercutt, M. G.; And Others

    The document is the first part of a study conducted to evaluate policy-related research on police arrest discretion as an alternative solution to arrest. It presents the administrative summary of the Arrest Decisions as Preludes To? (ADAPT) project and contains scripts intended for use by police departments as a staff training device. The…

  5. Bed Bug Infestations and Control Practices in China: Implications for Fighting the Global Bed Bug Resurgence

    Directory of Open Access Journals (Sweden)

    Changlu Wang

    2011-04-01

    Full Text Available The bed bug resurgence in North America, Europe, and Australia has elicited interest in investigating the causes of the widespread and increasing infestations and in developing more effective control strategies. In order to extend global perspectives on bed bug management, we reviewed bed bug literature in China by searching five Chinese language electronic databases. We also conducted telephone interviews of 68 pest control firms in two cities during March 2011. In addition, we conducted telephone interviews to 68 pest control companies within two cities in March 2011. Two species of bed bugs (Cimex lectularius L. and Cimex hemipterus (F. are known to occur in China. These were common urban pests before the early1980s. Nationwide “Four-Pest Elimination” campaigns (bed bugs being one of the targeted pests were implemented in China from 1960 to the early 1980s. These campaigns succeeded in the elimination of bed bug infestations in most communities. Commonly used bed bug control methods included applications of hot water, sealing of bed bug harborages, physical removal, and applications of residual insecticides (mainly organophosphate sprays or dusts. Although international and domestic travel has increased rapidly in China over the past decade (2000–2010, there have only been sporadic new infestations reported in recent years. During 1999–2009, all documented bed bug infestations were found in group living facilities (military dormitories, worker dormitories, and prisons, hotels, or trains. One city (Shenzhen city near Hong Kong experienced significantly higher number of bed bug infestations. This city is characterized by a high concentration of migratory factory workers. Current bed bug control practices include educating residents, washing, reducing clutter, putting items under the hot sun in summer, and applying insecticides (pyrethroids or organophosphates. There have not been any studies or reports on bed bug insecticide

  6. PRESSURE FLUCTUATIONS IN GAS-SOLIDS FLUIDIZED BEDS

    Institute of Scientific and Technical Information of China (English)

    Hsiaotao Bi; Aihua Chen

    2003-01-01

    Pressure fluctuation data measured in a series of fluidized beds with diameters of 0.05, 0.1, 0.29, 0.60 and 1.56 m showed that the maximum amplitude or standard deviation increased with increasing the superficial gas velocity and static bed height for relatively shallow beds and became insensitive to the increase in static bed height in relatively deep beds. The amplitude appeared to be less dependent on the measurement location in the dense bed. Predictions based on bubble passage, bubble eruption at the upper bed surface and bed oscillation all failed to explain all observed trends and underestimated the amplitude of pressure fluctuations, suggesting that the global pressure fluctuations in gas-solids bubbling fluidized beds are the superposition of local pressure variations, bed oscillations and pressure waves generated from the bubble formation in the distributor region, bubble coalescence during their rise and bubble eruption at the upper bed surface.

  7. Modular Electric Propulsion Test Bed Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An all electric aircraft test bed is proposed to provide a dedicated development environment for the rigorous study and advancement of electrically powered...

  8. Ultra high temperature particle bed reactor design

    Science.gov (United States)

    Lazareth, Otto; Ludewig, Hans; Perkins, K.; Powell, J.

    1990-01-01

    A direct nuclear propulsion engine which could be used for a mission to Mars is designed. The main features of this reactor design are high values for I(sub sp) and very efficient cooling. This particle bed reactor consists of 37 cylindrical fuel elements embedded in a cylinder of beryllium which acts as a moderator and reflector. The fuel consists of a packed bed of spherical fissionable fuel particles. Gaseous H2 passes over the fuel bed, removes the heat, and is exhausted out of the rocket. The design was found to be neutronically critical and to have tolerable heating rates. Therefore, this particle bed reactor design is suitable as a propulsion unit for this mission.

  9. Modular Electric Propulsion Test Bed Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A hybrid electric aircraft simulation system and test bed is proposed to provide a dedicated development environment for the rigorous study and advancement of...

  10. IceBridge BedMachine Greenland

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains bed topography beneath the Greenland Ice Sheet based on mass conservation derived from airborne radar tracks and satellite radar. The data...

  11. The effect of vibration on bed voidage behaviors in fluidized beds with large particles

    Directory of Open Access Journals (Sweden)

    H. Jin

    2007-09-01

    Full Text Available The effects of vibration parameters, operating conditions and material properties on bed voidage were investigated using an optical fiber probe approach in a vibrating fluidized bed with a diameter of 148 mm. Variables studied included frequency (0-282 s-1, amplitude (0 mm-1 mm, bed height (0.1 m-0.4 m as well as four kinds of particles (belonging to Geldart's B and D groups. The axial and radial voidage distribution with vibration is compared with that without vibration, which shows vibration can aid in the fluidization behaviors of particles. For a larger vibration amplitude, the vibration seriously affects bed voidage. The vibration energy can damp out for particle layers with increasing the bed height. According to analysis of experimental data, an empirical correlation for predicting bed voidage, giving good agreement with the experimental data and a deviation within ±15%, was proposed.

  12. The effect of vibration on bed voidage behaviors in fluidized beds with large particles

    Energy Technology Data Exchange (ETDEWEB)

    Jin, H.; Zhang, J.; Zhang, B.

    2007-07-01

    The effects of vibration parameters, operating conditions and material properties on bed voidage were investigated using an optical fiber probe approach in a vibrating fluidized bed with a diameter of 148 mm. Variables studied included frequency (0-282 s{sup -1}), amplitude (0 mm-1 mm), bed height (0.1 m-0.4 m) as well as four kinds of particles (belonging to Geldart's B and D groups). The axial and radial voidage distribution with vibration is compared with that without vibration, which shows vibration can aid in the fluidization behaviors of particles. For a larger vibration amplitude, the vibration seriously affects bed voidage. The vibration energy can damp out for particle layers with increasing the bed height. According to analysis of experimental data, an empirical correlation for predicting bed voidage, giving good agreement with the experimental data and a deviation within {+-}15%, was proposed. 20 refs., 8 figs., 2 tabs.

  13. Bed dynamics of gas-solid fluidized bed with rod promoter

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The dynamic characteristics of a gas-solid fluidized bed with different rod promoters have been investigated in terms of bed expansion and fluctuation, minimum fluidization velocity and distributor-to-bed pressure drop ratio at minimum fluidization velocity. Experimentation based on statistical design has been carried out and model equations using factorial design of experiments have been developed for the above mentioned quantities for a promoted gas-solid fluidized bed. The model equations have been tested with additional experimental data. The system variables include four types of rod promoters of varying blockage volume, bed particles of four sizes and four initial static bed heights. A comparison between the predicted values of the output variables using the proposed model equation with their corresponding experimental ones shows fairly good agreement.

  14. Experimental study and local approach of cleavage crack arrest in a bainitic steel

    International Nuclear Information System (INIS)

    EDF wants to complete the assessment of reactor pressure vessels, usually based on crack initiation concept, by crack arrest concept. The work aims at improving the knowledge of cleavage crack arrest in a reactor pressure vessel steel. For that purpose, isothermal crack arrest experiments were performed for temperatures ranging from - 150 C up to - 50 C on compact tensile specimens and on pre-cracked rings submitted to compressive loading. Fractographic observations revealed that the whole crack propagation and arrest occurs by cleavage even if ductile tearing occurs before initiation of the unstable crack propagation. A local cleavage crack arrest criterion is applied in finite element computations carried out in elasto-visco-plasticity and in full dynamics: the crack propagates since the largest principal stress reaches a critical stress. The application of this criterion on the experiments leads to a good prediction of the crack speed and of the crack length and shows that the critical stress increases with the temperature in relation with dissipation features observed on the fracture surfaces. Dependence to the geometry is observed; it can be due to the assumption used for the 2D computations. The study of the structural dynamic shows that the crack arrest phenomenon is very linked to the global dynamics of the structure: crack arrest and crack closure occur approximately at the same time. (author)

  15. Early Recognition of Foreign Body Aspiration as the Cause of Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Muhammad Kashif

    2016-01-01

    Full Text Available Foreign body aspiration (FBA is uncommon in the adult population but can be a life-threatening condition. Clinical manifestations vary according to the degree of airway obstruction, and, in some cases, making the correct diagnosis requires a high level of clinical suspicion combined with a detailed history and exam. Sudden cardiac arrest after FBA may occur secondary to asphyxiation. We present a 48-year-old male with no history of cardiac disease brought to the emergency department after an out-of-hospital cardiac arrest (OHCA. The patient was resuscitated after 15 minutes of cardiac arrest. He was initially managed with therapeutic hypothermia (TH. Subsequent history suggested FBA as a possible etiology of the cardiac arrest, and fiberoptic bronchoscopy demonstrated a piece of meat and bone lodged in the left main stem bronchus. The foreign body was removed with the bronchoscope and the patient clinically improved with full neurological recovery. Therapeutic hypothermia following cardiac arrest due to asphyxia has been reported to have high mortality and poor neurological outcomes. This case highlights the importance of early identification of FBA causing cardiac arrest, and we report a positive neurological outcome for postresuscitation therapeutic hypothermia following cardiac arrest due to asphyxia.

  16. Cognitive and emotional functioning in BED

    OpenAIRE

    Kittel, Rebekka; Brauhardt, Anne; Hilbert, Anja

    2016-01-01

    Objective: Binge-eating disorder (BED) is characterized by recurrent episodes of binge eating and is associated with eating disorder and general psychopathology and overweight/obesity. Deficits in cognitive and emotional functioning for eating disorders or obesity have been reported. However, a systematic review on cognitive and emotional functioning for individuals with BED is lacking. Method: A systematic literature search was conducted across three databases (Medline, PubMed, and PsycI...

  17. Suicide following an infestation of bed bugs

    OpenAIRE

    Burrows, Stephanie; Perron, Stéphane; Susser, Stephanie

    2013-01-01

    Patient: Male, 62 Final Diagnosis: Bipolar disorder Symptoms: Bordeline personality disorder Medication: — Clinical Procedure: Bed bug infestation Specialty: Psychiatry Objective: Unusual clinical course Background: In the past decade, bed bug infestations have been increasingly common in high income countries. Psychological consequences of these infestations are rarely examined in the scientific literature. Case Report: We present a case, based on a coroner’s investigation report, of a woman...

  18. Bed Bug Infestations and Control Practices in China: Implications for Fighting the Global Bed Bug Resurgence

    OpenAIRE

    Changlu Wang; Xiujun Wen

    2011-01-01

    The bed bug resurgence in North America, Europe, and Australia has elicited interest in investigating the causes of the widespread and increasing infestations and in developing more effective control strategies. In order to extend global perspectives on bed bug management, we reviewed bed bug literature in China by searching five Chinese language electronic databases. We conducted telephone interviews of staff from 77 Health and Epidemic Prevention Stations in six Chinese cities in November 2...

  19. Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p.

    OpenAIRE

    Cherkasova, V; Lyons, D M; Elion, E A

    1999-01-01

    In Saccharomyces cerevisiae, mating pheromones activate two MAP kinases (MAPKs), Fus3p and Kss1p, to induce G1 arrest prior to mating. Fus3p is known to promote G1 arrest by activating Far1p, which inhibits three Clnp/Cdc28p kinases. To analyze the contribution of Fus3p and Kss1p to G1 arrest that is independent of Far1p, we constructed far1 CLN strains that undergo G1 arrest from increased activation of the mating MAP kinase pathway. We find that Fus3p and Kss1p both control G1 arrest throug...

  20. Performance analysis of surge arrester on high voltage systems using ATP

    Energy Technology Data Exchange (ETDEWEB)

    Nallagownden, P.; Magumane, A.H. [Univ. Teknologi Petronas, Perak (Malaysia); Kanth, K.S.R. [Tenaga National Berhad (Malaysia)

    2008-07-01

    Lightning strikes are among the major factors that cause failures in electrical power systems. Phase to ground arresters are commonly installed at power transformer terminals to offer some lightning protection. However, it is important to understand the performance of metal oxide arresters under very fast transient overvoltages in order to determine the protection zone of the arrester and to achieve economical benefits. This study investigated lightning overvoltage protection in a complete three-phase scheme of a 500 KV substation. Overvoltages originated from direct lightning stroke on a phase of a real overhead line (OHL) model. The effect of the separation distance of the arrester from the transformer connected at the open end of the substations was investigated as well as the performance of the arrester for different substation configurations. In the first scenario, the connection of the arrester and transformer was done with a direct connection of an overhead line. In the second scenario, the connection of these devices was done through a cable. Both the overhead line and cable lengths were varied and the maximum overvoltages coming to the transformer were recorded. The results showed that there is a direct proportionality between overvoltages and length of the overhead line or cable. As long the length of the line or cable between the arrester and the transformer was increased, the vulnerability of the transformer to receive high overvoltages also increased. Surge overvoltages were found to be very sensitive to impedance of the line or cable. The direct connections of overhead lines between the arrester and transformer make it necessary to add some protective device. It was suggested that surge arresters should be installed every 200 meters along the overhead lines in order to ensure the safety of equipment. 12 refs., 4 tabs., 8 figs.

  1. Investigation of volumetrically heated debris bed quenching

    Energy Technology Data Exchange (ETDEWEB)

    Konovalikhin, M.J.; Sehgal, B.R. [Royal Institute of Technology, Div. of Nuclear Power Safety, Stockholm (Sweden)

    2001-07-01

    A series of experiments were conducted at RIT (Royal Institute of Technology) in which hot homogeneous and stratified particle beds were quenched by establishing a column of water onto the top of the bed and by injection of water from the bottom delivered through downcomers from the water overlayer. For this experimental program the following approach was adopted. Since corium debris have a particle size distribution and are more like sand, the debris beds were built with sand of different particle size distributions, heated with a network of thin heaters, distributed uniformly in the sand bed to produce uniform volumetric heat generation. Low porosity beds were constructed, since they are the most difficult to quench with top flooding. The primary objective was to obtain data, which will provide a phenomenological basis for assessing margins for coolability of a degraded core debris bed in the lower head of an LWR vessel as well as steam generation rate from the interactions between core debris and water. This paper summarizes the experimental results along with related analysis. (authors)

  2. CFD-DEM study of effect of bed thickness for bubbling fluidized beds

    Energy Technology Data Exchange (ETDEWEB)

    Tingwen, Li; Gopalakrishnan, Pradeep; Garg, Rahul; Shahnam, Mehrdad

    2011-10-01

    The effect of bed thickness in rectangular fluidized beds is investigated through the CFD–DEM simulations of small-scale systems. Numerical results are compared for bubbling fluidized beds of various bed thicknesses with respect to particle packing, bed expansion, bubble behavior, solids velocities, and particle kinetic energy. Good two-dimensional (2D) flow behavior is observed in the bed having a thickness of up to 20 particle diameters. However, a strong three-dimensional (3D) flow behavior is observed in beds with a thickness of 40 particle diameters, indicating the transition from 2D flow to 3D flow within the range of 20–40 particle diameters. Comparison of velocity profiles near the walls and at the center of the bed shows significant impact of the front and back walls on the flow hydrodynamics of pseudo-2D fluidized beds. Hence, for quantitative comparison with experiments in pseudo-2D columns, the effect of walls has to be accounted for in numerical simulations.

  3. WTP Pretreatment Facility Potential Design Deficiencies--Sliding Bed and Sliding Bed Erosion Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, E. K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-05-06

    This assessment is based on readily available literature and discusses both Newtonian and non-Newtonian slurries with respect to sliding beds and erosion due to sliding beds. This report does not quantify the size of the sliding beds or erosion rates due to sliding beds, but only assesses if they could be present. This assessment addresses process pipelines in the Pretreatment (PT) facility and the high level waste (HLW) transfer lines leaving the PT facility to the HLW vitrification facility concentrate receipt vessel.

  4. CFD-DEM study of effect of bed thickness for bubbling fluidized beds

    Institute of Scientific and Technical Information of China (English)

    Tingwen Li; Pradeep Gopalakrishnana; Rahul Garg; Mehrdad Shahnam

    2012-01-01

    The effect of bed thickness in rectangular fluidized beds is investigated through the CFD-DEM simulations of small-scale systems.Numerical results are compared for bubbling fluidized beds of various bed thicknesses with respect to particle packing,bed expansion,bubble behavior,solids velocities,and particle kinetic energy.Good two-dimensional (2D) flow behavior is observed in the bed having a thickness of up to 20 particle diameters.However,a strong three-dimensional (3D) flow behavior is observed in beds with a thickness of 40 particle diameters,indicating the transition from 2D flow to 3D flow within the range of 20-40 particle diameters.Comparison of velocity profiles near the walls and at the center of the bed shows significant impact of the front and back walls on the flow hydrodynamics of pseudo-2D fluidized beds.Hence,for quantitative comparison with experiments in pseudo-2D columns,the effect of wails has to be accounted for in numerical simulations.

  5. Prehospital behaviour of patients admitted with acute coronary syndrome or witnessed cardiac arrest

    DEFF Research Database (Denmark)

    Ottesen, Michael Mundt; Dixen, Ulrik; Torp-Pedersen, Christian;

    2003-01-01

    OBJECTIVE: To study prehospital behaviour of patients admitted with acute coronary syndrome or witnessed cardiac arrest. DESIGN: Structured interview of 250 consecutive patients with acute coronary syndrome and relatives of 48 patients with witnessed cardiac arrest. The following courses of action......-four per cent of the patients admitted with cardiac arrest expressed no prior symptoms. Two-thirds of patients with typical symptoms interpreted it as cardiac-still only half took action within 20 min. Fifty per cent of patients who called a physician were delayed by wrong advice or misinterpretation. One...

  6. Analysis on Lighting Withstand Characteristics of Polymeric ZnO Surge Arrester for Transmission Line against Lightning Overvoltages

    Energy Technology Data Exchange (ETDEWEB)

    Han, S.W.; Cho, H.G. [Korea Electrotechnology Research Institute, Changwon (Korea); He, J.L. [Tsinghua University, Beijing (Switzerland)

    2000-02-01

    The purpose of this study is to discuss the lightning withstand levels (LWLs) of two 110 kV transmission lines before and after line arresters made with polymeric housing are installed on the towers, the lightning discharging currents through arresters and lightning energies absorbed by line arresters. The LWLs can be highly increased by installing line arresters on the transmission line towers in parallel with the insulator strings. It is not problem that the polymeric ZnO surge arresters are used in transmission lines to limit lightning overvoltages. (author). 9 refs., 11 figs., 1 tab.

  7. A Literature Review Revisiting Phenytoin-Induced Sinus Arrest.

    Science.gov (United States)

    Parsai, Shireen; Hariri, Imad; Taleb, Mohammad; Yoon, Youngsook

    2016-01-01

    Classically, phenytoin (PTN) infusion for the treatment of status epilepticus has been proven to be associated with cardiovascular toxicity, including dysrhythmias, hypotension, and cardiovascular collapse. Subsequently, fosphenytoin (FOS) was introduced on the market in 1997 with claims of having less cardiac toxicity. However, since then, many accounts of cardiac events have been reported undermining these claims. FOS gained popularity due to its water solubility, which allows 3 times faster infusion in comparison with PTN with less venous irritation and local toxicity. FOS is the phosphate ester prodrug of PTN and is rapidly converted to PTN independent of the dose and rate of administration. Intravenous FOS and PTN are bioequivalent. Adverse cardiac effects of both intravenous FOS and PTN have been correlated to the rate of infusion, concentration of the agent, known risk factors, or pre-existing hypersensitivity, and most cases have been identified after infusing a loading dose of these medications. This case report is unique, in that, the patient developed sinus arrest while concurrently receiving oral PTN and intravenous FOS. Clinicians should be more cognizant of the association of FOS and PTN with adverse cardiac events. Baseline electrocardiogram should be obtained on all patients prescribed FOS or PTN to identify underlying cardiac problems that may place the patient in a higher risk category. Telemetry should be performed on all patients receiving PTN in an inpatient setting. PMID:25549077

  8. Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice.

    Science.gov (United States)

    Keenan, Craig M; Preston, Andrew J; Sutherland, Hazel; Wilson, Peter J; Psarelli, Eftychia E; Cox, Trevor F; Ranganath, Lakshminarayan R; Jarvis, Jonathan C; Gallagher, James A

    2015-01-01

    Alkaptonuria (AKU) is an ultrarare autosomal recessive disorder resulting from a deficiency of homogentisate 1,2 dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. Loss of HGD function prevents metabolism of homogentisic acid (HGA), leading to increased levels of plasma HGA and urinary excretion. Excess HGA becomes deposited in collagenous tissues and subsequently undergoes polymerisation, principally in the cartilages of loaded joints, in a process known as ochronosis. This results in an early-onset, devastating osteoarthropathy for which there is currently no effective treatment. We recently described the natural history of ochronosis in a murine model of AKU, demonstrating that deposition of ochronotic pigment begins very early in life and accumulates with age. Using this model, we were able to show that lifetime treatment with nitisinone, a potential therapy for AKU, was able to completely prevent deposition of ochronotic pigment. However, although nitisinone has been shown to inhibit ochronotic deposition, whether it can also facilitate removal of existing pigment has not yet been examined. We describe here that midlife administration of nitisinone to AKU mice arrests further deposition of ochronotic pigment in the tibiofemoral joint, but does not result in the clearance of existing pigment. We also demonstrate the dose-dependent response of plasma HGA to nitisinone, highlighting its efficacy for personalised medicine, where dosage can be tailored to the individual AKU patient. PMID:25940034

  9. A Literature Review Revisiting Phenytoin-Induced Sinus Arrest.

    Science.gov (United States)

    Parsai, Shireen; Hariri, Imad; Taleb, Mohammad; Yoon, Youngsook

    2016-01-01

    Classically, phenytoin (PTN) infusion for the treatment of status epilepticus has been proven to be associated with cardiovascular toxicity, including dysrhythmias, hypotension, and cardiovascular collapse. Subsequently, fosphenytoin (FOS) was introduced on the market in 1997 with claims of having less cardiac toxicity. However, since then, many accounts of cardiac events have been reported undermining these claims. FOS gained popularity due to its water solubility, which allows 3 times faster infusion in comparison with PTN with less venous irritation and local toxicity. FOS is the phosphate ester prodrug of PTN and is rapidly converted to PTN independent of the dose and rate of administration. Intravenous FOS and PTN are bioequivalent. Adverse cardiac effects of both intravenous FOS and PTN have been correlated to the rate of infusion, concentration of the agent, known risk factors, or pre-existing hypersensitivity, and most cases have been identified after infusing a loading dose of these medications. This case report is unique, in that, the patient developed sinus arrest while concurrently receiving oral PTN and intravenous FOS. Clinicians should be more cognizant of the association of FOS and PTN with adverse cardiac events. Baseline electrocardiogram should be obtained on all patients prescribed FOS or PTN to identify underlying cardiac problems that may place the patient in a higher risk category. Telemetry should be performed on all patients receiving PTN in an inpatient setting.

  10. ASPECTS REGARDING THE IMPLEMENTATION OF THE EUROPEAN ARREST WARRANT

    Directory of Open Access Journals (Sweden)

    Catalin, MARINESCU

    2014-11-01

    Full Text Available The Treaty of Amsterdam stipulated the fact that the European Union must maintain and develop an area of freedom, security and justice, freedom assuming the existence of a common judicial area in which European citizens are able to seek justice in any of the member state same as in their own country. This goal aims to eliminate the possibility that criminals exploit the differences between the legal systems of the member states, imposing that the judgments are recognized and enforced abroad without the formalities laid down by the classical conventions on international judicial assistance. The Council Framework Decision 2002/584/JHA of 13 June 2002 on the European arrest warrant and the surrender procedures between Member States, materialized the decision taken in Tampere, following that between EU Member States to be replace the formal extradition procedure of the people who evade the execution of a sentence of imprisonment imposed by a judgment of conviction became final, with a simplified surrender procedure..

  11. Dexmedetomidine Related Bradycardia Leading to Cardiac Arrest in a Dog

    Directory of Open Access Journals (Sweden)

    C. Y. Chen2, K-S. Chen1,2, K. M. Chang2, W. M. Lee1,2, S. C. Chang1,2 and H. C. Wang1,2

    2012-10-01

    Full Text Available A 2-year-old, mixed breed female dog (16 kg underwent an exploratory laparotomy following ultrasonographic diagnosis of foreign body and a segment of small intestine intussusceptions. The patient was classified as an ASA II. Ketamine (1mg/kg, IV, and dexmedetomidine (2.5 µg/kg, IV, and morphine (0.6 mg/kg, SC were given as anesthetic premedication. Propofol (0.1 mg/kg, IV titrated to a total amount of 4 ml (2.5 mg/ kg was given for intubation. Asystole was occurred. Cardiac resuscitation was then conducted immediately. Atipamezole (0.1 ml was injected, but showed no response on ECG. Atropine (0.02 mg/kg was then injected, and a second dosage was given. Two-three mins later, the heart rate at 84 beats/min. The NIBP showed 203/132 with MAP 153 mmHg, and the SpO2 showed 95% after the cardiac function was regained. Dexmedetomidine related bradycardia leading to cardiac arrest has been suggested in this case.

  12. A conservative approach to esthetically treat stained arrested caries lesions.

    Science.gov (United States)

    Al-Angari, Sarah S; Hara, Anderson T

    2016-01-01

    Esthetic treatment of stained arrested caries lesions (ACLs) has mostly been done using invasive restorative techniques. The aim of this paper was to propose and report the efficacy of a conservative approach based on dental bleaching to esthetically treat these lesions, both experimentally (extracted teeth) and clinically. In a laboratory experiment, ten extracted human teeth with stained ACLs in either pit and fissure or smooth surface were selected and treated with 15% carbamide peroxide gel, 4 h per day, for a total of 6 days. The second part of the paper reports a clinical case of pit and fissure-stained ACLs in four posterior teeth, which were treated with 40% hydrogen peroxide in-office bleaching. Digital photographs were taken in both parts to document the efficacy of the treatment. The lesions showed noticeable increase in color lightness indicating the efficacy and suitability of the proposed approach. By using the conservative clinical technique presented, the esthetics of most stained ACLs could be improved, eliminating the need for invasive restorative treatments. PMID:27092359

  13. Near-death experiences in cardiac arrest survivors.

    Science.gov (United States)

    French, Christopher C

    2005-01-01

    Near-death experiences (NDEs) have become the focus of much interest in the last 30 years or so. Such experiences can occur both when individuals are objectively near to death and also when they simply believe themselves to be. The experience typically involves a number of different components including a feeling of peace and well-being, out-of-body experiences (OBEs), entering a region of darkness, seeing a brilliant light, and entering another realm. NDEs are known to have long-lasting transformational effects upon those who experience them. An overview is presented of the various theoretical approaches that have been adopted in attempts to account for the NDE. Spiritual theories assume that consciousness can become detached from the neural substrate of the brain and that the NDE may provide a glimpse of an afterlife. Psychological theories include the proposal that the NDE is a dissociative defense mechanism that occurs in times of extreme danger or, less plausibly, that the NDE reflects memories of being born. Finally, a wide range of organic theories of the NDE has been put forward including those based upon cerebral hypoxia, anoxia, and hypercarbia; endorphins and other neurotransmitters; and abnormal activity in the temporal lobes. Finally, the results of studies of NDEs in cardiac arrest survivors are reviewed and the implications of these results for our understanding of mind-brain relationships are discussed.

  14. Efficiency of Super-Eddington Magnetically-Arrested Accretion

    CERN Document Server

    McKinney, Jonathan C; Avara, Mark

    2015-01-01

    The radiative efficiency of super-Eddington accreting black holes (BHs) is explored for magnetically-arrested disks (MADs), where magnetic flux builds-up to saturation near the BH. Our three-dimensional general relativistic radiation magnetohydrodynamic (GRRMHD) simulation of a spinning BH (spin $a/M=0.8$) accreting at $\\sim 50$ times Eddington shows a total efficiency $\\sim 50\\%$ when time-averaged and total efficiency $\\gtrsim 100\\%$ in moments. Magnetic compression by the magnetic flux near the rotating BH leads to a thin disk, whose radiation escapes via advection by a magnetized wind and via transport through a low-density channel created by a Blandford-Znajek (BZ) jet. The BZ efficiency is sub-optimal due to inertial loading of field lines by optically thick radiation, leading to BZ efficiency $\\sim 40\\%$ on the horizon and BZ efficiency $\\sim 5\\%$ by $r\\sim 400r_g$ (gravitational radii) via absorption by the wind. Importantly, radiation escapes at $r\\sim 400r_g$ with efficiency $\\eta\\approx 15\\%$ (lumi...

  15. Efficiency of Thin Magnetically-Arrested Disks Around Black Holes

    CERN Document Server

    Avara, Mark J; Reynolds, Chris S

    2015-01-01

    The radiative and jet efficiencies of thin magnetized accretion disks around black holes (BHs) are affected by BH spin and the presence of a magnetic field that, when strong, could lead to large deviations from Novikov-Thorne (NT) thin disk theory. To seek the maximum deviations, we perform general relativistic magnetohydrodynamic (GRMHD) simulations of radiatively efficient thin (half-height $H$ to radius $R$ of $H/R\\approx 0.10$) disks around moderately rotating BHs with $a/M=0.5$. First, our simulations, evolved for $108,000r_g/c$ (gravitational radius $r_g$ and speed of light $c$), show that large-scale magnetic field readily accretes inward even through our thin disk and builds-up to the magnetically-arrested disk (MAD) state. Second, our simulations of thin MADs show the disk achieves a radiative efficiency of $\\eta_{\\rm r}\\approx 15\\%$ (after estimating photon capture), which is about twice the NT value of $\\eta_{\\rm r}\\sim 8\\%$ for $a/M=0.5$ and gives the same luminosity as a NT disk with $a/M\\approx ...

  16. Cadmium and zinc reversibly arrest development of Artemia larvae

    Energy Technology Data Exchange (ETDEWEB)

    Bagshaw, J.C.; Rafiee, P.; Matthews, C.O.; MacRae, T.H.

    1986-08-01

    Despite the widespread distribution of heavy metals such as cadmium and zinc in the environment and their well-known cytotoxicity and embryotoxicity in mammals, comparatively little is known about their effect on aquatic organisms, particularly invertebrates. Post-gastrula and early larval development of the brine shrimp, Artemia, present some useful advantages for studies of developmental aspects of environmental toxicology. Dormant encysted gastrulae, erroneously called brine shrimp eggs, can be obtained commercially and raised in the laboratory under completely defined conditions. Following a period of post-gastrula development within the cyst, pre-nauplius larvae emerge through a crack in the cyst shell. A few hours later, free-swimming nauplius larvae hatch. Cadmium is acutely toxic to both adults and nauplius larvae of Artemia, but the reported LC50s are as high as 10 mM, depending on larval age. In this paper the authors show that pre-nauplius larvae prior to hatching are much more sensitive to cadmium than are hatched nauplius larvae. At 0.1 ..mu..m, cadmium retards development and hatching of larvae; higher concentrations block hatching almost completely and thus are lethal. However, the larvae arrested at the emergence stage survive for 24 hours or more before succumbing to the effects of cadmium, and during this period the potentially lethal effect is reversible if the larvae are placed in cadmium-free medium. The effects of zinc parallel those of cadmium, although zinc is somewhat less toxic than cadmium at equal concentrations.

  17. DNA damage mediated transcription arrest: Step back to go forward.

    Science.gov (United States)

    Mullenders, Leon

    2015-12-01

    The disturbance of DNA helix conformation by bulky DNA damage poses hindrance to transcription elongating due to stalling of RNA polymerase at transcription blocking lesions. Stalling of RNA polymerase provokes the formation of R-loops, i.e. the formation of a DNA-RNA hybrid and a displaced single stranded DNA strand as well as displacement of spliceosomes. R-loops are processed into DNA single and double strand breaks by NER factors depending on TC-NER factors leading to genome instability. Moreover, stalling of RNA polymerase induces a strong signal for cell cycle arrest and apoptosis. These toxic and mutagenic effects are counteracted by a rapid recruitment of DNA repair proteins to perform transcription coupled nucleotide excision repair (TC-NER) to remove the blocking DNA lesions and to restore transcription. Recent studies have highlighted the role of backtracking of RNA polymerase to facilitate TC-NER and identified novel factors that play key roles in TC-NER and in restoration of transcription. On the molecular level these factors facilitate stability of the repair complex by promotion and regulation of various post-translational modifications of NER factors and chromatin substrate. In addition, the continuous flow of new factors that emerge from screening assays hints to several regulatory levels to safeguard the integrity of transcription elongation after disturbance by DNA damage that have yet to be explored.

  18. 21 CFR 880.5140 - Pediatric hospital bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Pediatric hospital bed. 880.5140 Section 880.5140... Devices § 880.5140 Pediatric hospital bed. (a) Identification. A pediatric hospital bed is a device intended for medical purposes that consists of a bed or crib designed for the use of a pediatric...

  19. 21 CFR 880.5110 - Hydraulic adjustable hospital bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hydraulic adjustable hospital bed. 880.5110... Therapeutic Devices § 880.5110 Hydraulic adjustable hospital bed. (a) Identification. A hydraulic adjustable hospital bed is a device intended for medical purposes that consists of a bed with a hydraulic...

  20. 21 CFR 892.1350 - Nuclear scanning bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nuclear scanning bed. 892.1350 Section 892.1350...) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1350 Nuclear scanning bed. (a) Identification. A nuclear scanning bed is an adjustable bed intended to support a patient during a nuclear...

  1. 21 CFR 880.5120 - Manual adjustable hospital bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual adjustable hospital bed. 880.5120 Section... Therapeutic Devices § 880.5120 Manual adjustable hospital bed. (a) Identification. A manual adjustable hospital bed is a device intended for medical purposes that consists of a bed with a manual...

  2. The Petrographic Distinction between Basalt and Andesite Based upon the Arrested Fractionation of Plagioclase Phenocrysts.

    Science.gov (United States)

    Garlick, G. Donald; Garlick, Benjamin J.

    1987-01-01

    Discusses the need to take into account the effects of arrested fractional crystallization in the petrographic classification of volcanic rocks containing plagioclase phenocrysts. Describes the development and use of a computer program to accomplish this task graphically. (TW)

  3. Parameter identification of ZnO surge arrester models based on genetic algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Bayadi, Abdelhafid [Laboratoire d' Automatique de Setif, Departement d' Electrotechnique, Faculte des Sciences de l' Ingenieur, Universite Ferhat ABBAS de Setif, Route de Bejaia Setif 19000 (Algeria)

    2008-07-15

    The correct and adequate modelling of ZnO surge arresters characteristics is very important for insulation coordination studies and systems reliability. In this context many researchers addressed considerable efforts to the development of surge arresters models to reproduce the dynamic characteristics observed in their behaviour when subjected to fast front impulse currents. The difficulties with these models reside essentially in the calculation and the adjustment of their parameters. This paper proposes a new technique based on genetic algorithm to obtain the best possible series of parameter values of ZnO surge arresters models. The validity of the predicted parameters is then checked by comparing the predicted results with the experimental results available in the literature. Using the ATP-EMTP package, an application of the arrester model on network system studies is presented and discussed. (author)

  4. Interfacial Crack Arrest in Sandwich Panels with Embedded Crack Stoppers Subjected to Fatigue Loading

    Science.gov (United States)

    Martakos, G.; Andreasen, J. H.; Berggreen, C.; Thomsen, O. T.

    2016-08-01

    A novel crack arresting device has been implemented in sandwich panels and tested using a special rig to apply out-of-plane loading on the sandwich panel face-sheets. Fatigue crack propagation was induced in the face-core interface of the sandwich panels which met the crack arrester. The effect of the embedded crack arresters was evaluated in terms of the achieved enhancement of the damage tolerance of the tested sandwich panels. A finite element (FE) model of the experimental setup was used for predicting propagation rates and direction of the crack growth. The FE simulation was based on the adoption of linear fracture mechanics and a fatigue propagation law (i.e. Paris law) to predict the residual fatigue life-time and behaviour of the test specimens. Finally, a comparison between the experimental results and the numerical simulations was made to validate the numerical predictions as well as the overall performance of the crack arresters.

  5. Developmental arrest of germ cells in the pathogenesis of germ cell neoplasia

    DEFF Research Database (Denmark)

    Rajpert-De Meyts, E; Jørgensen, N; Brøndum-Nielsen, K;

    1998-01-01

    hypothesise that if the development of the testis is disturbed or delayed, primordial germ cells or gonocytes undergo maturation delay or differentiation arrest which may render them susceptible to neoplastic transformation. Morphologically homogenous premalignant carcinoma in situ (CIS) cells have...

  6. Biofilm Community Dynamics in Bench-Scale Annular Reactors Simulating Arrestment of Chloraminated Drinking Water Nitrification

    Science.gov (United States)

    Annular reactors (ARs) were used to study biofilm community succession and provide an ecological insight during nitrification arrestment through simultaneously increasing monochloramine (NH2Cl) and chlorine to nitrogen mass ratios, resulting in four operational periods (I to IV)....

  7. Therapeutic Hypothermia and Out-of-Hospital Cardiac Arrest in a Child with Hypertrophic Obstructive Cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Nancy Spurkeland

    2015-01-01

    Full Text Available Neurologic outcomes following pediatric cardiac arrest are consistently poor. Early initiation of cardiopulmonary resuscitation has been shown to have positive effects on both survival to hospital discharge, and improved neurological outcomes after cardiac arrest. Additionally, the use of therapeutic hypothermia may improve survival in pediatric cardiac arrest patients admitted to the intensive care unit. We report a child with congenital hypertrophic obstructive cardiomyopathy and an out-of-hospital cardiac arrest, in whom the early initiation of effective prolonged cardiopulmonary resuscitation and subsequent administration of therapeutic hypothermia contributed to a positive outcome with no gross neurologic sequelae. Continuing efforts should be made to promote and employ high-quality cardiopulmonary resuscitation, which likely contributed to the positive outcome of this case. Further research will be necessary to develop and solidify national guidelines for the implementation of therapeutic hypothermia in selected subpopulations of children with OHCA.

  8. Study of the Electric Filed Around a Metal Oxide Surge Arrester: Measurement and Simulation

    Institute of Scientific and Technical Information of China (English)

    Christodoulou C A; Spanias C A; Kontargyri V T; Gonos I F; Stathopulos I A

    2013-01-01

    The study of the electric field around a surge arrester is useful for design procedures and diagnostic tests.The current work computes the electric field around a medium voltage gapless surge arrester using 2D and 3D representation of the arrester.The 2D simulation design,which is described in IEC 60099-4 Standard,cannot include the non symmetrical parts of the arrester geometry and the test arrangement.3D simulation procedures have the advantage that takes into account these asymmetries,giving more accurate results for each measurement position.In order to confirm the suitability of the created models,the simulation results of the electric field,using the 2D and 3D edition of PC Opera,are compared with recorded measurements,which are obtained in laboratory using appropriate calibrated field meters.

  9. Impact of substance abuse treatment on arrests among opiate users in Washington State.

    Science.gov (United States)

    Campbell, Kevin M; Deck, Dennis; Krupski, Antoinette

    2007-01-01

    Administrative data from Washington State's Division of Alcohol and Substance Abuse drive this three-year prospective study of the impact of substance abuse treatment on arrests among 12,962 opiate users receiving publicly funded substance abuse services. Using survival analysis, the risk of arrest among opiate users who receive substance abuse treatment is compared to those who do not receive treatment. Propensity scores control for client characteristics associated with admission to substance abuse treatment. Overall, a reduction in the risk of arrest was found among subjects in treatment (Hazard Ratio = 0.59-0.78, p < .05) and subjects successfully completing treatment (Hazard Ratio = 0.75, p < .05). Risk of arrest was elevated among those with a negative outcome to treatment (Hazard Ratio = 1.23, p < .05).

  10. EU Citizenship and European Arrest Warrant: The Same Rights for All?

    Directory of Open Access Journals (Sweden)

    Tony Marguery

    2011-06-01

    Full Text Available In the case Wolzenburg, the principle of non-discrimination of European Union citizens is applied to the European arrest warrant. The implementation of the European arrest warrant by the Member States cannot escape a control of proportional- ity made by the Court. Member States may impose a period of residence of five years to foreign Europeans citizens in order for them to rely on an optional ground for non-execution of a European arrest warrant (Article 4(6 of the Framework Deci- sion on the European arrest warrant. Home nationals are not obliged to comply with a residence requirement. It is possible for Member States to justify an exception to the principle of non-discrimination of European citizens with a legitimate inter- est. The chances of social reintegration of a person convicted constitute such an interest. The national measure resulting in a difference of treatment must be proportional to that interest.

  11. Optimizing Neurologically Intact Survival from Sudden Cardiac Arrest: A Call to Action

    Directory of Open Access Journals (Sweden)

    Jeffrey M. Goodloe

    2014-11-01

    Full Text Available The U.S. national out-of-hospital and in-hospital cardiac arrest survival rates, although improving recently, have remained suboptimal despite the collective efforts of individuals, communities, and professional societies. Only until very recently, and still with inconsistency, has focus been placed specifically on survival with pre-arrest neurologic function. The reality of current approaches to sudden cardiac arrest is that they are often lacking an integrative, multi-disciplinary approach, and without deserved funding and outcome analysis. In this manuscript, a multidisciplinary group of authors propose practice, process, technology, and policy initiatives to improve cardiac arrest survival with a focus on neurologic function. [West J Emerg Med. 2014;15(7:-0.

  12. Bed and breakfasts in Virginia :identification and success factors

    OpenAIRE

    Kaufman, Tammie J

    1994-01-01

    Virginia bed and breakfast operations were researched in order to determine the attitudes/beliefs which were necessary for success in the bed and breakfast industry. The objectives of the study were to: (1) identify demographics of Virginia bed and breakfast operations; (2) identify successful bed and breakfast operations based upon their self definition of success; (3) identify the attitudes and beliefs operators believe are necessary for success in running a bed and breakf...

  13. Experiments on the dryout behavior of stratified debris beds

    Energy Technology Data Exchange (ETDEWEB)

    Leininger, Simon; Kulenovic, Rudi; Laurien, Eckart [Stuttgart Univ. (Germany). Inst. of Nuclear Technology and Energy Systems (IKE)

    2015-10-15

    In case of a severe accident with loss of coolant and core meltdown a particle bed (debris) can be formed. The removal of decay heat from the debris bed is of prime importance for the bed's long-term coolability to guarantee the integrity of the RPV. In contrast to previous experiments, the focus is on stratified beds. The experiments have pointed out that the bed's coolability is significantly affected.

  14. NONUNIFORM OPEN CHANNEL FLOW WITH UPWARD SEEPAGE THROUGH LOOSE BEDS

    Institute of Scientific and Technical Information of China (English)

    Subhasish DEY

    2003-01-01

    The Reynolds stress and bed shear stress are important parameters in fluvial hydraulics. Steadynonuniform flow in open channels with streamwise sloping beds having upward seepage through loose beds is theoretically analyzed to estimate the Reynolds stress and bed shear stress. Equations of the Reynolds stress and bed shear stress are developed, assuming a modified logarithmic velocity distribution law due to upward seepage, and using the Reynolds and continuity equations of twodimensional flow in open channels.

  15. Theoretical comparison of packed bed and fluidized bed membrane reactors for methane reforming

    NARCIS (Netherlands)

    Gallucci, Fausto; Sint Annaland, van Martin; Kuipers, J.A.M.

    2010-01-01

    In this theoretical work the performance of different membrane reactor concepts, both fluidized bed and packed bed membrane reactors, has been compared for ultra-pure hydrogen production via methane reforming. Using detailed theoretical models, the required membrane area to reach a given conversion

  16. Fluidized-bed and packed-bed characteristics of gel beads

    NARCIS (Netherlands)

    Zessen, van E.; Tramper, J.; Rinzema, A.; Beeftink, H.H.

    2005-01-01

    A liquid-fluidized bed or packed bed with gel beads is attractive as an immobilized-cell bioreactor. The performance of such bioreactors is influenced by the physical behavior of these beads. Three different but related aspects involving the drag force between particles and liquid were studied for f

  17. Radiological analyses of France Telecom surge arresters. Study performed for the CGT FAPT Cantal

    International Nuclear Information System (INIS)

    This document reports the radiological characterization of various versions of surge arresters used in the past to protect telephone lines against over-voltages. These equipment, which use various radioactive materials, were assessed by gamma radiation flow measurements, alpha-beta-gamma count rate measurements, dose rate measurements, gamma spectrometry analyses, tritium emanation test, radon 222 emanation test, smearing. Recommendations are formulated to manage radioactive surge arresters which are still being operated

  18. Multimodal Imaging after Sudden Cardiac Arrest in an 18-Year-Old Athlete

    Science.gov (United States)

    Rehman, Mobeen Ur; Atalay, Michael K.; Broderick, Ryan J.

    2015-01-01

    We report the case of a previously healthy 18-year-old male athlete who twice presented with sudden cardiac arrest. Our use of electrocardiography, echocardiography, cardiac magnetic resonance, coronary angiography, coronary computed tomographic angiography, and nuclear stress testing enabled the diagnoses of apical hypertrophic cardiomyopathy and anomalous origin of the right coronary artery. We discuss the patient's treatment and note the useful role of multiple cardiovascular imaging methods in cases of sudden cardiac arrest. PMID:26664308

  19. Difference of cell cycle arrests induced by lidamycin in human breast cancer cells.

    Science.gov (United States)

    Liu, Xia; He, Hongwei; Feng, Yun; Zhang, Min; Ren, Kaihuan; Shao, Rongguang

    2006-02-01

    Lidamycin (LDM) is a member of the enediyne antibiotic family. It is undergoing phase I clinical trials in China as a potential chemotherapeutic agent. In the present study, we investigated the mechanism by which LDM induced cell cycle arrest in human breast cancer cells. The results showed that LDM induced G1 arrest in p53 wild-type MCF-7 cells at low concentrations, and caused both G1 and G2/M arrests at higher concentrations. In contrast, LDM induced only G2/M arrest in p53-mutant MCF-7/DOX cells. Western blotting analysis indicated that LDM-induced G1 and G2/M arrests in MCF-7 cells were associated with an increase of p53 and p21, and a decrease of phosphorylated retinoblastoma tumor suppressor protein, cyclin-dependent kinase (Cdk), Cdc2 and cyclin B1 protein levels. However, LDM-induced G2/M arrest in MCF-7/DOX cells was correlated with the reduction of cyclin B1 expression. Further study indicated that the downregulation of cyclin B1 by LDM in MCF-7 cells was associated with decreasing cyclin B1 mRNA levels and promoting protein degradation, whereas it was only due to inducing cyclin B1 protein degradation in MCF-7/DOX cells. In addition, activation of checkpoint kinases Chk1 or Chk2 maybe contributed to LDM-induced cell cycle arrest. Taken together, we provide the first evidence that LDM induces different cell cycle arrests in human breast cancer cells, which are dependent on drug concentration and p53 status. These findings are helpful in understanding the molecular anti-cancer mechanisms of LDM and support its clinical trials. PMID:16428935

  20. Why Do Increased Arrest Rates Appear to Reduce Crime: Deterrence, Incapacitation, or Measurement Error?

    OpenAIRE

    Steven D. Levitt

    1995-01-01

    A strong, negative empirical correlation exists between arrest rates and reported crime rates. While this relationship has often been interpreted as support for the deterrence hypothesis, it is equally consistent with incapacitation effects, and/or a spurious correlation that would be induced by measurement error in reported crime rates. This paper attempts to discriminate between deterrence, incapacitation, and measurement error as explanations for the empirical relationship between arrest r...

  1. Parameters Calculation of ZnO Surge Arrester Models by Genetic Algorithms

    Directory of Open Access Journals (Sweden)

    A. Bayadi

    2006-09-01

    Full Text Available This paper proposes to provide a new technique based on the genetic algorithm to obtain the best possible series of values of the parameters of the ZnO surge arresters models. The validity of the predicted parameters is then checked by comparing the results predicted with the experimental results available in the literature. Using the ATP-EMTP package an application of the arrester model on network system studies is presented and discussed.

  2. TGEV nucleocapsid protein induces cell cycle arrest and apoptosis through activation of p53 signaling

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Li [College of Veterinary Medicine, Northwest A and F University, Yangling, Shaanxi 712100 (China); College of Life Sciences, Hainan Normal University, Haikou, Hainan 571158 (China); Huang, Yong; Du, Qian; Dong, Feng; Zhao, Xiaomin; Zhang, Wenlong; Xu, Xingang [College of Veterinary Medicine, Northwest A and F University, Yangling, Shaanxi 712100 (China); Tong, Dewen, E-mail: dwtong@nwsuaf.edu.cn [College of Veterinary Medicine, Northwest A and F University, Yangling, Shaanxi 712100 (China)

    2014-03-07

    Highlights: • TGEV N protein reduces cell viability by inducing cell cycle arrest and apoptosis. • TGEV N protein induces cell cycle arrest and apoptosis by regulating p53 signaling. • TGEV N protein plays important roles in TGEV-induced cell cycle arrest and apoptosis. - Abstract: Our previous studies showed that TGEV infection could induce cell cycle arrest and apoptosis via activation of p53 signaling in cultured host cells. However, it is unclear which viral gene causes these effects. In this study, we investigated the effects of TGEV nucleocapsid (N) protein on PK-15 cells. We found that TGEV N protein suppressed cell proliferation by causing cell cycle arrest at the S and G2/M phases and apoptosis. Characterization of various cellular proteins that are involved in regulating cell cycle progression demonstrated that the expression of N gene resulted in an accumulation of p53 and p21, which suppressed cyclin B1, cdc2 and cdk2 expression. Moreover, the expression of TGEV N gene promoted translocation of Bax to mitochondria, which in turn caused the release of cytochrome c, followed by activation of caspase-3, resulting in cell apoptosis in the transfected PK-15 cells following cell cycle arrest. Further studies showed that p53 inhibitor attenuated TGEV N protein induced cell cycle arrest at S and G2/M phases and apoptosis through reversing the expression changes of cdc2, cdk2 and cyclin B1 and the translocation changes of Bax and cytochrome c induced by TGEV N protein. Taken together, these results demonstrated that TGEV N protein might play an important role in TGEV infection-induced p53 activation and cell cycle arrest at the S and G2/M phases and apoptosis occurrence.

  3. Effect of four resuscitation methods on lung ventilation of pigs with respiratory arrest

    OpenAIRE

    Ya-hua LIU; Xiu-man LI; Li-xiang WANG

    2012-01-01

    Objective To observe the effects of four cardiopulmonary resuscitation (CPR) methods on lung ventilation of pigs with respiratory arrest. The four CPR methods included chest compression CPR (C-CPR), compression under the diaphragm CPR (D-CPR), abdominal compression CPR (A-CPR), and abdominal wall lifting and compression CPR (L-CPR). Methods  A total of 28 healthy domestic pigs were randomly divided into four groups. The pig respiratory arrest model was reproduced by intravenous injection of s...

  4. Antidepressant Use and Risk of Out-of-Hospital Cardiac Arrest

    DEFF Research Database (Denmark)

    Weeke, P; Jensen, Aksel Karl Georg; Folke, F;

    2012-01-01

    Treatment with some types of antidepressants has been associated with sudden cardiac death. It is unknown whether the increased risk is due to a class effect or related to specific antidepressants within drug classes. All patients in Denmark with an out-of-hospital cardiac arrest (OHCA) were.......17-12.2). An association between cardiac arrest and antidepressant use could be documented in both the SSRI and TCA classes of drugs....

  5. Hospital discharge diagnoses of ventricular arrhythmias and cardiac arrest were useful for epidemiologic research

    DEFF Research Database (Denmark)

    De Bruin, M L; van Hemel, N M; Leufkens, H G M;

    2005-01-01

    OBJECTIVE: We investigated the validity of hospital discharge diagnosis regarding ventricular arrhythmias and cardiac arrest. METHODS: We identified patients whose record in the PHARMO record linkage system database showed a code for ventricular or unspecified cardiac arrhythmias according to cod...... according to ICD-9-CM as paroxysmal ventricular tachycardia, ventricular fibrillation, ventricular flutter, ventricular premature beats, or cardiac arrest) have a high PPV and are useful for selecting events in epidemiological studies on drug-induced arrhythmias....

  6. Crack arrest model for a piezoelectric strip subjected to Mode-I loadings

    OpenAIRE

    R.R. Bhargava; Amit Setia

    2007-01-01

    Purpose: The present paper aims at proposing a crack arrest model for an infinitely long narrow, poledceramic strip weakened by a finite hairline straight crack when the edges of the strip are subjected to combinedmechanical and electrical loads.Design/methodology/approach: (Model) As a consequence of loads the rims of crack open forming a yieldzone ahead of each tip of the crack. To arrest the crack from further opening the rims of the yield zones aresubjected to normal cohesive quadraticall...

  7. Effects of Abusive Parenting, Caretaker Arrests, and Deviant Behavior on Dating Violence among Homeless Young Adults

    OpenAIRE

    Tyler, Kimberly A.; Schmitz, Rachel M.

    2015-01-01

    Though dating violence is widespread among young adult homeless populations, its risk factors are poorly understood by scholars. To address this gap, the current study uses a social learning theory to examine the effects of abusive parenting and caretaker arrests on dating violence among 172 homeless young adults. Results from path analyses revealed that child physical abuse and caretaker arrests were positively associated with engaging in a greater number of school fights, which, in turn, wa...

  8. The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

    OpenAIRE

    Bao\\xa0N. Puente; Wataru Kimura; Shalini\\xa0A. Muralidhar; Jesung Moon; James\\xa0F. Amatruda; Kate\\xa0L. Phelps; David Grinsfelder; Beverly\\xa0A. Rothermel; Rui Chen; Joseph\\xa0A. Garcia; Celio\\xa0X. Santos; SuWannee Thet; Eiichiro Mori; Michael\\xa0T. Kinter; Paul\\xa0M. Rindler

    2014-01-01

    The mammalian heart has a remarkable regenerative capacity for a short period of time after birth, after which the majority of cardiomyocytes permanently exit cell cycle. We sought to determine the primary post-natal event that results in cardiomyocyte cell-cycle arrest. We hypothesized that transition to the oxygen rich postnatal environment is the upstream signal that results in cell cycle arrest of cardiomyocytes. Here we show that reactive oxygen species (ROS), oxidative DNA damage, and D...

  9. Double Bolus Thrombolysis for Suspected Massive Pulmonary Embolism during Cardiac Arrest

    OpenAIRE

    Gerard O’Connor; Gareth Fitzpatrick; Ayman El-Gammal; Peadar Gilligan

    2015-01-01

    More than 70% of cardiac arrest cases are caused by acute myocardial infarction (AMI) or pulmonary embolism (PE). Although thrombolytic therapy is a recognised therapy for both AMI and PE, its indiscriminate use is not routinely recommended during cardiopulmonary resuscitation (CPR). We present a case describing the successful use of double dose thrombolysis during cardiac arrest caused by pulmonary embolism. Notwithstanding the relative lack of high-level evidence, this case suggests a scena...

  10. The thermal conductivity of beds of spheres

    Energy Technology Data Exchange (ETDEWEB)

    McElroy, D.L.; Weaver, F.J.; Shapiro, M.; Longest, A.W.; Yarbrough, D.W.

    1987-01-01

    The thermal conductivities (k) of beds of solid and hollow microspheres were measured using two radial heat flow techniques. One technique provided k-data at 300 K for beds with the void spaces between particles filled with argon, nitrogen, or helium from 5 kPa to 30 MPa. The other technique provided k-data with air at atmospheric pressure from 300 to 1000 K. The 300 K technique was used to study bed systems with high k-values that can be varied by changing the gas type and gas pressure. Such systems can be used to control the operating temperature of an irradiation capsule. The systems studied included beds of 500 ..mu..m dia solid Al/sub 2/O/sub 3/, the same Al/sub 2/O/sub 3/ spheres mixed with spheres of silica--alumina or with SiC shards, carbon spheres, and nickel spheres. Both techniques were used to determine the k-value of beds of hollow spheres with solid shells of Al/sub 2/O/sub 3/, Al/sub 2/O/sub 3//center dot/7 w/o Cr/sub 2/O/sub 3/, and partially stabilized ZrO/sub 2/. The hollow microspheres had diameters from 2100 to 3500 ..mu..m and wall thicknesses from 80 to 160 ..mu..m. 12 refs., 7 figs., 4 tabs.

  11. Nonlinear Mechanism of Bed Load Transport

    Institute of Scientific and Technical Information of China (English)

    XU Haijue; BAI Yuchuan; NG Chiu-On

    2009-01-01

    From the group movement of the bed load within the bottom layer, details of the nonlinear dynamic characteristics of bed load movement are discussed in this paper. Whether the sediment is initiated into motion cor-responds to whether the constant term in the equation is equal to zero. If constant term is zero and no dispersive force is considered, the equation represents the traditional Shields initiation curve, and if constant term is zero with-out the dispersive force being considered, then a new Shields curve which is much lower than the traditional one is got, The fixed point of the equation corresponds to the equilibrium sediment transport of bed load. In the mutation analysis, we have found that the inflection point is the demarcation point of breaking. In theory, the breaking point corresponds to the dividing boundary line, across which the bed form changes from flat bed to sand ripple or sand dune. Compared with the experimental data of Chatou Hydraulic Lab in France, the conclusions are verified.

  12. Spouted bed electrowinning of zinc: Part II. Investigations of the dynamics of particles in large thin spouted beds

    Science.gov (United States)

    Verma, A.; Evans, J. W.; Salas-Morales, Juan Carlos

    1997-02-01

    The behavior of particles in thin spouted beds, mostly equipped with draft tubes, has been investigated. Three apparatuses have been used: a laboratory-scale cylindrical bed, a 2-m-tall “flat” (rectangular cross section) bed and a 2-m-wide flat bed, the last equipped with multiple draft tubes. Most of the results were obtained on the tall bed. Minimum spouting flow rate, pressure distribution, particle velocities, and solid circulation rates were determined as a function of bed geometry (including draft tube dimensions and position). Observations were made of the direction of liquid flow in the bed outside the draft tube and of the occurrence of zones in the bed where the particles appeared stationary. The wide bed was used to determine that there is a maximum separation between draft tubes beyond which particles cannot be kept in motion across the whole width of the bed.

  13. Sudden cardiac arrest in a patient with epilepsy induced by chronic inflammation on the cerebral surface

    Institute of Scientific and Technical Information of China (English)

    Yuxi Liu; Weicheng Hao; Xiaoming Yang; Yimin Wang; Yu Su

    2012-01-01

    The present study analyzed a patient with epilepsy due to chronic inflammation on the cerebral surface underwent sudden cardiac arrest. Paradoxical brain discharge, which occurred prior to epileptic seizures, induced a sudden cardiac arrest. However, when the focal brain pressure was relieved, cardiac arrest disappeared. A 27-year-old male patient underwent pre-surgical video-electroencephalogram monitoring for 160 hours. During monitoring, secondary tonic-clonic seizures occurred five times. A burst of paradoxical brain discharges occurred at 2-19 seconds (mean 8 seconds) prior to epileptic seizures. After 2-3 seconds, sudden cardiac arrest occurred and lasted for 12-22 seconds (average 16 seconds). The heart rate subsequently returned to a normal rate. Results revealed arachnoid pachymenia and adhesions, as well as mucus on the focal cerebral surface, combined with poor circulation and increased pressure. Intracranial electrodes were placed using surgical methods. Following removal of the arachnoid adhesions and mucus on the local cerebral surface, paradoxical brain discharge and epileptic seizures occurred three times, but sudden cardiac arrest was not recorded during 150-hour monitoring. Post-surgical histological examination indicated meningitis. Experimental findings suggested that paradoxical brain discharge led to cardiac arrest instead of epileptic seizures; the insult was associated with chronic inflammation on the cerebral surface, which subsequently led to hypertension and poor blood circulation in focal cerebral areas.

  14. A new on-line leakage current monitoring system of ZnO surge arresters

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Bok-Hee [Research Center for Next-Generation High Voltage and Power Technology, Inha University, 253 Yonghyun-dong, Nam-ku, Incheon 402-751 (Korea, Republic of)]. E-mail: bhlee@inha.ac.kr; Kang, Sung-Man [Research Center for Next-Generation High Voltage and Power Technology, Inha University, 253 Yonghyun-dong, Nam-ku, Incheon 402-751 (Korea, Republic of)

    2005-05-15

    This paper presents a new on-line leakage current monitoring system of zinc oxide (ZnO) surge arresters. To effectively diagnose the deterioration of ZnO surge arresters, a new algorithm and on-line leakage current detection device, which uses the time-delay addition method, for discriminating the resistive and capacitive currents was developed to use in the aging test and durability evaluation for ZnO arrester blocks. A computer-based measurement system of the resistive leakage current, the on-line monitoring device can detect accurately the leakage currents flowing through ZnO surge arresters for power frequency ac applied voltages. The proposed on-line leakage current monitoring device of ZnO surge arresters is more highly sensitive and gives more linear response than the existing devices using the detection method of the third harmonic leakage currents. Therefore, the proposed leakage current monitoring device can be useful for predicting the defects and performance deterioration of ZnO surge arresters in power system applications.

  15. Assessment of surge arrester failure rate and application studies in Hellenic high voltage transmission lines

    Energy Technology Data Exchange (ETDEWEB)

    Christodoulou, C.A.; Fotis, G.P.; Gonos, I.F.; Stathopulos, I.A. [National Technical University of Athens, School of Electrical and Computer Engineering, High Voltage Laboratory, 9 Iroon Politechniou St., Zografou Campus, 157 80 Athens (Greece); Ekonomou, L. [A.S.PE.T.E. - School of Pedagogical and Technological Education, Department of Electrical Engineering Educators, N. Heraklion, 141 21 Athens (Greece)

    2010-02-15

    The use of transmission line surge arresters to improve the lightning performance of transmission lines is becoming more common. Especially in areas with high soil resistivity and ground flash density, surge arresters constitute the most effective protection mean. In this paper a methodology for assessing the surge arrester failure rate based on the electrogeometrical model is presented. Critical currents that exceed arresters rated energy stress were estimated by the use of a simulation tool. The methodology is applied on operating Hellenic transmission lines of 150 kV. Several case studies are analyzed by installing surge arresters on different intervals, in relation to the region's tower footing resistance and the ground flash density. The obtained results are compared with real records of outage rate showing the effectiveness of the surge arresters in the reduction of the recorded failure rate. The presented methodology can be proved valuable to the studies of electric power systems designers intending in a more effective lightning protection, reducing the operational costs and providing continuity of service. (author)

  16. Co-ordination of spark-gap protection with zinc-oxide surge arresters

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, A.; German, D.M.; Waters, R.T. [Cardiff Univ., School of Engineering, Cardiff (United Kingdom); Abdul-Malek, Z. [University of Technology (Malaysia)

    2001-01-01

    Zinc-oxide (ZnO) surge arresters are now well established as a very efficient and reliable form of overvoltage protection against both fast surges, such as those generated by lightning and gas-insulated switchgear, and high-energy surges generated by switching operations and temporary faults on the network. The addition of ZnO surge arresters to existing protection schemes reinforces the system's reliability and the security of supply. The protection characteristics of the parallel configuration formed by arresters and existing spark gaps at distribution voltages are studied. Tests on various spark-gap geometries, with and without surge arresters in parallel, have been carried out to determine breakdown characteristics, probability curves and voltage-time characteristics for different impulse shapes. It is found that the introduction of the arrester in the circuit modifies the prospective impulse which results in the shift of the breakdown characteristics towards higher voltages. A proposed circuit model, based on laboratory test data, is used to simulate such parallel configurations. Good agreement between test and simulated results is obtained. As a result of these tests, it is recommended that gap-sparkover characteristics based on short-tail (about 5{mu}s) impulses are used for insulation co-ordination. The role of parallel airgaps in preserving the arrester energy-rating limits is also discussed. (Author)

  17. Use of Sodium Bicarbonate in Cardiac Arrest: Current Guidelines and Literature Review.

    Science.gov (United States)

    Velissaris, Dimitrios; Karamouzos, Vassilios; Pierrakos, Charalampos; Koniari, Ioanna; Apostolopoulou, Christina; Karanikolas, Menelaos

    2016-04-01

    The aim of the review was to summarize the literature over the last 25 years regarding bicarbonate administration in out-of-hospital cardiac arrest. A PubMed search was conducted using the terms "bicarbonates" and "cardiac arrest", limited to human studies and reviews published in English (or at least with a meaningful abstract in English) in the last 25 years. Clinical and experimental data raised questions regarding the safety and effectiveness of sodium bicarbonate (SB) administration during cardiac arrest. Earlier advanced cardiac life support (ACLS) guidelines recommended routine bicarbonate administration as part of the ACLS algorithm, but recent guidelines no longer recommend its use. The debate in the literature is ongoing, but at the present time, SB administration is only recommended for cardiac arrest related to hypokalemia or overdose of tricyclic antidepressants. Several studies challenge the assumption that bicarbonate administration is beneficial for treatment of acidosis in cardiac arrest. At the present time, there is a trend against using bicarbonates in cardiac arrest, and this trend is supported by guidelines published by professional societies and organizations. PMID:26985247

  18. Master curve based correlation between static initiation toughness KIC and crack arrest toughness KIa

    International Nuclear Information System (INIS)

    Historically the ASME reference curve concept assumes a constant relation between static fracture toughness initiation toughness and crack arrest toughness. In reality, this is not the case. Experimental results show that the difference between KIC and KIa is material specific. For some materials there is a big difference while for others they nearly coincide. So far, however, no systematic study regarding a possible correlation between the two parameters has been performed. The recent Master curve method, developed for brittle fracture initiation estimation, has enabled a consistent analysis of fracture initiation toughness data. The Master curve method has been modified to be able to describe also crack arrest toughness. Here, this modified 'crack arrest master curve' is further validated and used to develop a simple, but yet (for safety assessment purpose) adequately accurate correlation between the two fracture toughness parameters. The correlation enables the estimation of crack arrest toughness from small Charpy-sized static fracture toughness tests. The correlation is valid for low Nickel steels ≤ (1.2% Ni). If a more accurate description of the crack arrest toughness is required, it can either be measured experimentally or estimated from instrumented Charpy-V crack arrest load information. (orig.)

  19. Incidence of out-of-hospital cardiac arrest.

    Science.gov (United States)

    Rea, Thomas D; Pearce, Rachel M; Raghunathan, Trivellore E; Lemaitre, Rozenn N; Sotoodehnia, Nona; Jouven, Xavier; Siscovick, David S

    2004-06-15

    Estimates of the incidence of out-of-hospital primary cardiac arrest (CA) have typically relied solely upon emergency medical service or death certificate records and have not investigated incidence in clinical subgroups. Overall and temporal patterns of CA incidence were investigated in clinically defined groups using systematic methods to ascertain CA. Estimates of incidence were derived from a population-based case-control study in a large health plan from 1986 to 1994. Subjects were enrollees aged 50 to 79 years who had had CA (n = 1,275). A stratified random sample of enrollees who had not had CA was used to estimate the population at risk with various clinical characteristics (n = 2,323). Poisson's regression was used to estimate incidence overall and for 3-year time periods (1986 to 1988, 1989 to 1991, and 1992 to 1994). The overall CA incidence was 1.89/1,000 subject-years and varied up to 30-fold across clinical subgroups. For example, incidence was 5.98/1,000 subject-years in subjects with any clinically recognized heart disease compared with 0.82/1,000 subject-years in subjects without heart disease. In subgroups with heart disease, incidence was 13.69/1,000 subject-years in subjects with prior myocardial infarction and 21.87/1,000 subject-years in subjects with heart failure. Risk decreased by 20% from the initial to the final time period, with a greater decrease observed in those with (25%) compared with those without (12%) clinical heart disease. Thus, CA incidence varied considerably across clinical groups. The results provide insights regarding absolute and population-attributable risk in clinically defined subgroups, information that may aid strategies aimed at reducing mortality from CA. PMID:15194012

  20. Mechanisms involved in alternariol-induced cell cycle arrest

    International Nuclear Information System (INIS)

    Alternariol (AOH), a mycotoxin produced by Alternaria sp, is often found as a contaminant in fruit and cereal products. Here we employed the murine macrophage cell line RAW 264.7 to test the hypothesis that AOH causes toxicity as a response to DNA damage. AOH at concentrations of 15–30 μM almost completely blocked cell proliferation. Within 30 min treatment, AOH (30 μM) significantly increased the level of reactive oxygen species (ROS). Furthermore, DNA base oxidations as well as DNA strand breaks and/or alkaline labile sites were detected by the comet assay after 2 h exposure of AOH. Cell death (mostly necrosis) was observed after prolonged exposure to the highest concentration of AOH (60 μM for 24 and 48 h) in our study. The DNA damage response involved phosphorylation (activation) of histone H2AX and check point kinase-1- and 2 (Chk-1/2). Moreover, AOH activated p53 and increased the expression of p21, Cyclin B, MDM2, and Sestrin 2; likewise the level of several miRNA was affected. AOH-induced Sestrin 2 expression was regulated by p53 and could at least partly be inhibited by antioxidants, suggesting a role of ROS in the response. Interestingly, the addition of antioxidants did not inhibit cell cycle arrest. Although the formation of ROS by itself was not directly linked cell proliferation, AOH-induced DNA damage and resulting transcriptional changes in p21, MDM2, and Cyclin B likely contribute to the reduced cell proliferation; while Sestrin 2 would contribute to the oxidant defense.

  1. Efficiency of thin magnetically arrested discs around black holes

    Science.gov (United States)

    Avara, Mark J.; McKinney, Jonathan C.; Reynolds, Christopher S.

    2016-10-01

    The radiative and jet efficiencies of thin magnetized accretion discs around black holes (BHs) are affected by BH spin and the presence of a magnetic field that, when strong, could lead to large deviations from Novikov-Thorne (NT) thin disc theory. To seek the maximum deviations, we perform general relativistic magnetohydrodynamic simulations of radiatively efficient thin (half-height H to radius R of H/R ≈ 0.10) discs around moderately rotating BHs with a/M = 0.5. First, our simulations, each evolved for more than 70 000 rg/c (gravitational radius rg and speed of light c), show that large-scale magnetic field readily accretes inward even through our thin disc and builds-up to the magnetically arrested disc (MAD) state. Secondly, our simulations of thin MADs show the disc achieves a radiative efficiency of ηr ≈ 15 per cent (after estimating photon capture), which is about twice the NT value of ηr ˜ 8 per cent for a/M = 0.5 and gives the same luminosity as an NT disc with a/M ≈ 0.9. Compared to prior simulations with ≲10 per cent deviations, our result of an ≈80 per cent deviation sets a new benchmark. Building on prior work, we are now able to complete an important scaling law which suggests that observed jet quenching in the high-soft state in BH X-ray binaries is consistent with an ever-present MAD state with a weak yet sustained jet.

  2. Mechanisms involved in alternariol-induced cell cycle arrest

    Energy Technology Data Exchange (ETDEWEB)

    Solhaug, A., E-mail: Anita.Solhaug@vetinst.no [Norwegian Veterinary Institute, Oslo (Norway); Vines, L.L. [Michigan State University, Department of Food Science and Human Nutrition, East Lansing, MI (United States); Ivanova, L.; Spilsberg, B. [Norwegian Veterinary Institute, Oslo (Norway); Holme, J.A. [Norwegian Institute of Public Health, Division of Environmental Medicine, Oslo (Norway); Pestka, J. [Michigan State University, Department of Food Science and Human Nutrition, East Lansing, MI (United States); Collins, A. [University of Oslo, Department of Nutrition, Faculty of Medicine, Oslo (Norway); Eriksen, G.S. [Norwegian Veterinary Institute, Oslo (Norway)

    2012-10-15

    Alternariol (AOH), a mycotoxin produced by Alternaria sp, is often found as a contaminant in fruit and cereal products. Here we employed the murine macrophage cell line RAW 264.7 to test the hypothesis that AOH causes toxicity as a response to DNA damage. AOH at concentrations of 15-30 {mu}M almost completely blocked cell proliferation. Within 30 min treatment, AOH (30 {mu}M) significantly increased the level of reactive oxygen species (ROS). Furthermore, DNA base oxidations as well as DNA strand breaks and/or alkaline labile sites were detected by the comet assay after 2 h exposure of AOH. Cell death (mostly necrosis) was observed after prolonged exposure to the highest concentration of AOH (60 {mu}M for 24 and 48 h) in our study. The DNA damage response involved phosphorylation (activation) of histone H2AX and check point kinase-1- and 2 (Chk-1/2). Moreover, AOH activated p53 and increased the expression of p21, Cyclin B, MDM2, and Sestrin 2; likewise the level of several miRNA was affected. AOH-induced Sestrin 2 expression was regulated by p53 and could at least partly be inhibited by antioxidants, suggesting a role of ROS in the response. Interestingly, the addition of antioxidants did not inhibit cell cycle arrest. Although the formation of ROS by itself was not directly linked cell proliferation, AOH-induced DNA damage and resulting transcriptional changes in p21, MDM2, and Cyclin B likely contribute to the reduced cell proliferation; while Sestrin 2 would contribute to the oxidant defense.

  3. The Arrested Black Men in Europe: Criminal or Victim?

    Directory of Open Access Journals (Sweden)

    Michael Platzer

    2007-12-01

    Full Text Available The Africans detained in Austria have been targeted by police by their skin color, often are arrested with violence, are poorly defended by assigned defense lawyers, given longer sentences than Austrian citizens and have less access to alternatives or bail.A modified form of the United Nations Crime Victim questionnaire was administered to all the African prisoners at the Vienna’s Central Detention Facility. It revealed that the Africans were not only victims of violence (sometimes even torture and crimes (assault-58%, burglary-32%, fraud-27%, bribery-33% in their home countries, but also 24 percent had experienced assault, 16% theft, and 13% had been defrauded in Austria-much higher rates than the EU citizen. On the other hand, the Africans are rarely charged with burglary, robbery, or violent crimes. They are primarily arrested for the possession or sale of narcotic drugs (83% and an additional four percent for resisting arrest. This is primarily the result of insufficient financial support provided to asylum seekers and the prohibition to work pending their determination of immigrant status. Because of the long appeal processes and the practical impossibility of deporting certain nationalities, a type of underground community is taking root where simple survival is the determining factor whether to commit a non-violent offence. Les Africains détenus en Autriche sont visés par la police à cause de la couleur de leur peau; ils sont souvent arrêtés avec violence, sont mal défendus par leurs avocats de défense, doivent passer de plus longues périodes en prison que des citoyens autrichiens ayant commis un crime pareil, et ils ont moins d'accès aux mesures extrajudiciaires et au système de liberté sous caution. Une forme modifiée du questionnaire de victimes de crime des Nations Unies fut administrée à tous les prisonniers africains au Service Central de la Détention de Vienne. Les résultats indiquèrent que les Africains furent

  4. Rock bed heat accumulators. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Riaz, M.

    1977-12-01

    The principal objectives of the research program on rock bed heat accumulators (or RBHA) are: (1) to investigate the technical and economic feasibility of storing large amounts of thermal energy (in the tens of MWt range) at high temperature (up to 500/sup 0/C) over extended periods of time (up to 6 months) using native earth or rock materials; (2) to conduct studies to establish the performance characteristics of large rock bed heat accumulators at various power and temperature levels compatible with thermal conversion systems; and (3) to assess the materials and environmental problems associated with the operation of such large heat accumulators. Results of the study indicate that rock bed heat accumulators for seasonal storage are both technically and economically feasible, and hence could be exploited in various applications in which storage plays an essential role such as solar power and total energy systems, district and cogeneration heating systems.

  5. Tube erosion in bubbling fluidized beds

    Energy Technology Data Exchange (ETDEWEB)

    Levy, E.K. [Lehigh Univ., Bethlehem, PA (United States). Energy Research Center; Stallings, J.W. [Electric Power Research Inst., Palo Alto, CA (United States)

    1991-12-31

    This paper reports on experimental and theoretical studies that were preformed of the interaction between bubbles and tubes and tube erosion in fluidized beds. The results are applicable to the erosion of horizontal tubes in the bottom row of a tube bundle in a bubbling bed. Cold model experimental data show that erosion is caused by the impact of bubble wakes on the tubes, with the rate of erosion increasing with the velocity of wake impact with the particle size. Wake impacts resulting from the vertical coalescence of pairs of bubbles directly beneath the tube result in particularly high rates of erosion damage. Theoretical results from a computer simulation of bubbling and erosion show very strong effects of the bed geometry and bubbling conditions on computed rates of erosion. These results show, for example, that the rate of erosion can be very sensitive to the vertical location of the bottom row of tubes with respect to the distributor.

  6. Novel Simulated moving bed technologies

    Energy Technology Data Exchange (ETDEWEB)

    Purdue University

    2003-12-30

    Cellulose and hemicellulose from plants and other biomass can be hydrolyzed to produce sugars (i.e. glucose and xylose). Once these sugars are separated from other impurities, they can serve as feedstock in fermentation to produce ethanol (as fuels), lactic acid, or other valuable chemicals. The need for producing fuels and chemicals from renewable biomass has become abundantly clear over the last decade. However, the cost of producing fermentable sugars from biomass hydrolyzate using existing technology is relatively high and has been a major obstacle. The objective of this project is to develop an efficient and economical simulated moving bed (SMB) process to recover fermentable sugars from biomass hydrolyzate. Sulfuric acid can hydrolyze the cellulose and hemicellulose in biomass to sugars, but this process can generate byproducts such as acetic acid, and can lead to further degradation of the xylose to furfural and glucose to hydroxymethyl furfural (HMF). Also, lignin and other compounds in the biomass will degrade to various phenolic compounds. If the concentrations of these compounds exceed certain threshold levels, they will be toxic to the downstream fermentation, and will severely limit the usefulness of the derived sugars. Standard post-hydrolysis processing involves neutralization of sulfuric acid, usually with lime (calcium hydroxide). A study by Wooley et al.showed that the limed hydrolyzate gave a low ethanol yield in fermentation test (20% of theoretical yield compared to 77% of theoretical yield from fermentation of pure sugars). They showed that instead of adding lime, an ion exclusion chromatography process could be used to remove acids, as well as to isolate the sugars from the biomass hydrolyzate. In this project, we investigated the feasibility of developing an economical SMB process based on (1) a polymeric adsorbent, Dowex99, which was used by Wooley et al., (2) a second polymeric adsorbent, poly-4-vinyl pyridine (or PVP in short, Reilly

  7. Exercise countermeasures for bed-rest deconditioning

    Science.gov (United States)

    Greenleaf, John (Editor)

    1993-01-01

    The purpose for this 30-day bed rest study was to investigate the effects of short-term, high intensity isotonic and isokinetic exercise training on maintenance of working capacity (peak oxygen uptake), muscular strength and endurance, and on orthostatic tolerance, posture and gait. Other data were collected on muscle atrophy, bone mineralization and density, endocrine analyses concerning vasoactivity and fluid-electrolyte balance, muscle intermediary metabolism, and on performance and mood of the subjects. It was concluded that: The subjects maintained a relatively stable mood, high morale, and high esprit de corps throughout the study. Performance improved in nearly all tests in almost all the subjects. Isotonic training, as opposed to isokinetic exercise training, was associated more with decreasing levels of psychological tension, concentration, and motivation; and improvement in the quality of sleep. Working capacity (peak oxygen uptake) was maintained during bed rest with isotonic exercise training; it was not maintained with isokinetic or no exercise training. In general, there was no significant decrease in strength or endurance of arm or leg muscles during bed rest, in spite of some reduction in muscle size (atrophy) of some leg muscles. There was no effect of isotonic exercise training on orthostasis, since tilt-table tolerance was reduced similarly in all three groups following bed rest. Bed rest resulted in significant decreases of postural stability and self-selected step length, stride length, and walking velocity, which were not influenced by either exercise training regimen. Most pre-bed rest responses were restored by the fourth day of recovery.

  8. Cardiac atrophy after bed rest and spaceflight

    Science.gov (United States)

    Perhonen, M. A.; Franco, F.; Lane, L. D.; Buckey, J. C.; Blomqvist, C. G.; Zerwekh, J. E.; Peshock, R. M.; Weatherall, P. T.; Levine, B. D.

    2001-01-01

    Cardiac muscle adapts well to changes in loading conditions. For example, left ventricular (LV) hypertrophy may be induced physiologically (via exercise training) or pathologically (via hypertension or valvular heart disease). If hypertension is treated, LV hypertrophy regresses, suggesting a sensitivity to LV work. However, whether physical inactivity in nonathletic populations causes adaptive changes in LV mass or even frank atrophy is not clear. We exposed previously sedentary men to 6 (n = 5) and 12 (n = 3) wk of horizontal bed rest. LV and right ventricular (RV) mass and end-diastolic volume were measured using cine magnetic resonance imaging (MRI) at 2, 6, and 12 wk of bed rest; five healthy men were also studied before and after at least 6 wk of routine daily activities as controls. In addition, four astronauts were exposed to the complete elimination of hydrostatic gradients during a spaceflight of 10 days. During bed rest, LV mass decreased by 8.0 +/- 2.2% (P = 0.005) after 6 wk with an additional atrophy of 7.6 +/- 2.3% in the subjects who remained in bed for 12 wk; there was no change in LV mass for the control subjects (153.0 +/- 12.2 vs. 153.4 +/- 12.1 g, P = 0.81). Mean wall thickness decreased (4 +/- 2.5%, P = 0.01) after 6 wk of bed rest associated with the decrease in LV mass, suggesting a physiological remodeling with respect to altered load. LV end-diastolic volume decreased by 14 +/- 1.7% (P = 0.002) after 2 wk of bed rest and changed minimally thereafter. After 6 wk of bed rest, RV free wall mass decreased by 10 +/- 2.7% (P = 0.06) and RV end-diastolic volume by 16 +/- 7.9% (P = 0.06). After spaceflight, LV mass decreased by 12 +/- 6.9% (P = 0.07). In conclusion, cardiac atrophy occurs during prolonged (6 wk) horizontal bed rest and may also occur after short-term spaceflight. We suggest that cardiac atrophy is due to a physiological adaptation to reduced myocardial load and work in real or simulated microgravity and demonstrates the plasticity

  9. Lake bed classification using acoustic data

    Science.gov (United States)

    Yin, Karen K.; Li, Xing; Bonde, John; Richards, Carl; Cholwek, Gary

    1998-01-01

    As part of our effort to identify the lake bed surficial substrates using remote sensing data, this work designs pattern classifiers by multivariate statistical methods. Probability distribution of the preprocessed acoustic signal is analyzed first. A confidence region approach is then adopted to improve the design of the existing classifier. A technique for further isolation is proposed which minimizes the expected loss from misclassification. The devices constructed are applicable for real-time lake bed categorization. A mimimax approach is suggested to treat more general cases where the a priori probability distribution of the substrate types is unknown. Comparison of the suggested methods with the traditional likelihood ratio tests is discussed.

  10. Numerical simulation of nuclear pebble bed configurations

    Energy Technology Data Exchange (ETDEWEB)

    Shams, A., E-mail: shams@nrg.eu [Nuclear Research and Consultancy Group (NRG), Petten (Netherlands); Roelofs, F., E-mail: roelofs@nrg.eu [Nuclear Research and Consultancy Group (NRG), Petten (Netherlands); Komen, E.M.J., E-mail: komen@nrg.eu [Nuclear Research and Consultancy Group (NRG), Petten (Netherlands); Baglietto, E., E-mail: emiliob@MIT.EDU [Massachusetts Institute of Technology (MIT) (United States)

    2015-08-15

    Highlights: • Numerical simulations of a single face cubic centred pebble bed are performed. • Wide range of turbulence modelling techniques are used to perform these calculations. • The methods include 1-DNS, 1-LES, 3-Hybrid (RANS/LES) and 3-RANS models, respectively. • The obtained results are extensively compared to provide guidelines for such flow regimes. • These guidelines are used to perform reference LES for a limited sized random pebble bed. - Abstract: High Temperature Reactors (HTRs) are being considered all over the world. An HTR uses helium gas as a coolant, while the moderator function is taken up by graphite. The fuel is embedded in the graphite moderator. A particular inherent safety advantage of HTR designs is that the graphite can withstand very high temperatures, that the fuel inside will stay inside the graphite pebble and cannot escape to the surroundings even in the event of loss of cooling. Generally, the core can be designed using a graphite pebble bed. Some experimental and demonstration reactors have been operated using a pebble bed design. The test reactors have shown safe and efficient operation, however questions have been raised about possible occurrence of local hot spots in the pebble bed which may affect the pebble integrity. Analysis of the fuel integrity requires detailed evaluation of local heat transport phenomena in a pebble bed, and since such phenomena cannot easily be modelled experimentally, numerical simulations are a useful tool. As a part of a European project, named Thermal Hydraulics of Innovative Nuclear Systems (THINS), a benchmarking quasi-direct numerical simulation (q-DNS) of a well-defined pebble bed configuration has been performed. This q-DNS will serve as a reference database in order to evaluate the prediction capabilities of different turbulence modelling approaches. A wide range of numerical simulations based on different available turbulence modelling approaches are performed and compared with

  11. Perspectives for Fluidized Bed Nuclear Reactor Technology using Rotating Fluidized Beds in a Static Geometry

    Science.gov (United States)

    Broqueville, Axel De; Wilde, Juray De

    The new concept of a rotating fluidized bed in a static geometry opens perspectives for fluidized bed nuclear reactor technology and is experimentally and numerically investigated. With conventional fluidized bed technology, the maximum attainable power is rather limited and maximum at a certain fluidization gas flow rate. Using a rotating fluidized bed in a static geometry, the fluidization gas drives both the centrifugal force and the counteracting radial gas-solid drag force in a similar way. This allows operating the reactor at any chosen sufficiently high solids loading over a much wider fluidization gas flow rate range and in particular at much higher fluidization gas flow rates than with conventional fluidized bed reactor technology, offering increased flexibility with respect to cooling via the fluidization gas. Furthermore, the centrifugal force can be a multiple of earth gravity, allowing radial gas-solid slip velocities much higher than in conventional fluidized beds. The latter result in gas-solid heat transfer coefficients one or multiple orders of magnitude higher than in conventional fluidized beds. The combination of dense operation and high fluidization gas flow rates allows process intensification and a more compact reactor design.

  12. Loading and Unloading Weaned Pigs: Effects of Bedding Types, Ramp Angle, and Bedding Moisture

    Directory of Open Access Journals (Sweden)

    Arlene Garcia

    2014-12-01

    Full Text Available The use of non-slip surfaces during loading and unloading of weaned pigs plays an important role in animal welfare and economics of the pork industry. Currently, the guidelines available only suggest the use of ramps below 20° to load and unload pigs. Three ramp angles (0°, 10° or 20°, five bedding materials (nothing, sand, feed, wood shavings or wheat straw hay, two moistures (dry or wet bedding; >50% moisture over two seasons (>23.9 °C summer, <23.9 °C winter were assessed for slips/falls/vocalizations (n = 6,000 pig observations. “Score” was calculated by the sum of slips, falls, and vocalizations. With the exception of using feed as a bedding, all beddings provided some protection against elevated slips, falls, and vocalizations (P < 0.01. Providing bedding reduced (P < 0.05 scores regardless of whether the bedding was dry or wet. Scores increased as the slope increased (P < 0.01. Provision of bedding, other than feed, at slopes greater than zero, decreased slips, falls and vocalizations. The total time it took to load and unload pigs was

  13. Effect of bed particles to combustion of gases in fluidized bed

    Energy Technology Data Exchange (ETDEWEB)

    Raiko, R.; Wallen, V.; Etelaeaho, R.; Correia, S. [Tampere Univ. of Technology (Finland). Energy and Process Engineering

    1997-10-01

    The objective of this project was to obtain experimental data on effects of sand particles to the combustion of gases. The effect of the surface area of the particles was tested using different sized particles. The fluidized bed reactor used in these experiments was a stainless-steel tube with an internal diameter of 42 mm surrounded by an electric heater. The test rig was built in the Laboratory of Energy and Process Engineering at Tampere University of Technology. In order to elucidate the possible changes of particle surface, microscopic and porosimetric studies were conducted with both fresh bed particles and used bed particles. These measurements indicate that carbon monoxide significantly reacts with oxygen in the particulate or emulsion phase of a fluidized bed, if the residence time is long enough. The reaction rate depends mainly on temperature, air coefficient, residence time and particle size of the solids. It seems that the combustion enhances if the average particle size increases. Whether this is caused by increased free path length or reduced specific surface area of the bed is yet unknown. The first might be more probable cause because the majority of reactions often took place in the freeboard right above the bed. It was clear that the bed hindered proper combustion in several cases. (orig.)

  14. From Modern Push-Button Hospital-beds to 20th Century Mechatronic Beds: A Review

    Science.gov (United States)

    Ghersi, I.; Mariño, M.; Miralles, M. T.

    2016-04-01

    The aim of this work is to present the different aspects of modern high complexity electric beds of the period 1940 until 2000 exclusively. The chronology of the product has been strictly divided into three big stages: electric and semi-electric beds (until the 90’s), mechatronic beds (90’s until 2000) and, mechatronic intelligent beds of the last 15 years. The latter are not considered in this work due to the extension for its analysis. The justification for classifying the product is presented under the concepts of medical, assistive and mobility devices. Relevant aspects of common immobility problems of the different types of patients for which the beds are mainly addressed are shown in detail. The basic functioning of the patient’s movement generator and the implementation of actuators, together with IT programs, specific accessories and connectivity means and network-communication shown in this work, were those that gave origin to current mechatronic beds. We present the historical evolution of high complexity electric beds by illustrating cases extracted from a meticulous time line, based on patents, inventions and publications in newspapers and magazines of the world. The criteria adopted to evaluate the innovation were: characteristics of controls; accessories (mattresses, lighting, siderails, etc.), aesthetic and morphologic properties and outstanding functionalities.

  15. Effects of bed-load movement on flow resistance over bed forms

    Indian Academy of Sciences (India)

    Mohammad Hossein Omid; Masoud Karbasi; Javad Farhoudi

    2010-12-01

    The effect of bed-load transport on flow resistance of alluvial channels with undulated bed was experimentally investigated. The experiments were carried out in a tilting flume 250 mm wide and 12·5 m long with glass-sides of rectangular cross-section and artificial dune shaped floor that was made from Plexi-glass. Steady flow of clear as against sediment-laden water with different flow depths and velocities were studied in the experiments with a fine sand ($d_{50} =$ 0·5 mm). The results indicate that the transport of fine particles ($d_{50} =$ 0·5 mm) can decrease the friction factor by 22% and 24% respectively for smooth and rough beds. Increasing the bed-load size ($d_{50} =$ 2·84 mm) can decrease the friction factor by 32% and 39% respectively for smooth and rough beds. The decrease in flow resistance is due to filling up of the troughs of dunes. This separation zone is responsible for increasing the flow resistance. On the upstream side of dunes condition is similar to plane bed. Presence of bed-load causes to increase the shear velocity and hence increasing flow resistance. But decreasing in flow resistance is more and it causes to decrease the total flow resistance. Grains saturated the troughs in the bed topography, effectively helping in smoothening of bed irregularities.

  16. Mineral resources of the Devil's Garden Lava Bed, Squaw Ridge Lava Bed, and Four Craters Lava Bed Wilderness Study Areas, Lake County, Oregon

    Energy Technology Data Exchange (ETDEWEB)

    Keith, W.J.; King, H.D.; Gettings, M.E. (Geological Survey, Reston, VA (USA)); Johnson, F.L. (US Bureau of Mines (US))

    1988-01-01

    The Devel's Garden lava Bed, Squaw Ridge Lava Bed, and Four Craters Lava Bed Wilderness Study Areas include approximately 70,940 acres and are underlain entirely by Pleistocene or Holocene lava flows and associated sediments. There is no evidence of hydrothermal alteration in the study areas. No resources were identified in the study areas, but there is low potential for perlite resources in the southern part of the Devil's Garden Lava Bed and the northern half of the Squaw Ridge Lava Bed areas. All three study areas have low potential for geothermal resources and for oil and gas resources.

  17. The Effects of Local Police Surges on Crime and Arrests in New York City

    Science.gov (United States)

    MacDonald, John; Fagan, Jeffrey; Geller, Amanda

    2016-01-01

    The New York Police Department (NYPD) under Operation Impact deployed extra police officers to high crime areas designated as impact zones. Officers were encouraged to conduct investigative stops in these areas. City officials credited the program as one of the leading causes of New York City’s low crime rate. We tested the effects of Operation Impact on reported crimes and arrests from 2004 to 2012 using a difference-in-differences approach. We used Poisson regression models to compare differences in crime and arrest counts before and after census block groups were designated as impact zones compared to census block groups in the same NYPD precincts but outside impact zones. Impact zones were significantly associated with reductions in total reported crimes, assaults, burglaries, drug violations, misdemeanor crimes, felony property crimes, robberies, and felony violent crimes. Impact zones were significantly associated with increases in total reported arrests, arrests for burglary, arrests for weapons, arrests for misdemeanor crimes, and arrests for property felony crimes. Impact zones were also significantly associated with increases in investigative stops for suspected crimes, but only the increase in stops made based on probable cause indicators of criminal behaviors were associated with crime reductions. The largest increase in investigative stops in impact zones was based on indicators of suspicious behavior that had no measurable effect on crime. The findings suggest that saturating high crime blocks with police helped reduce crime in New York City, but that the bulk of the investigative stops did not play an important role in the crime reductions. The findings indicate that crime reduction can be achieved with more focused investigative stops. PMID:27310252

  18. The Effects of Local Police Surges on Crime and Arrests in New York City.

    Directory of Open Access Journals (Sweden)

    John MacDonald

    Full Text Available The New York Police Department (NYPD under Operation Impact deployed extra police officers to high crime areas designated as impact zones. Officers were encouraged to conduct investigative stops in these areas. City officials credited the program as one of the leading causes of New York City's low crime rate. We tested the effects of Operation Impact on reported crimes and arrests from 2004 to 2012 using a difference-in-differences approach. We used Poisson regression models to compare differences in crime and arrest counts before and after census block groups were designated as impact zones compared to census block groups in the same NYPD precincts but outside impact zones. Impact zones were significantly associated with reductions in total reported crimes, assaults, burglaries, drug violations, misdemeanor crimes, felony property crimes, robberies, and felony violent crimes. Impact zones were significantly associated with increases in total reported arrests, arrests for burglary, arrests for weapons, arrests for misdemeanor crimes, and arrests for property felony crimes. Impact zones were also significantly associated with increases in investigative stops for suspected crimes, but only the increase in stops made based on probable cause indicators of criminal behaviors were associated with crime reductions. The largest increase in investigative stops in impact zones was based on indicators of suspicious behavior that had no measurable effect on crime. The findings suggest that saturating high crime blocks with police helped reduce crime in New York City, but that the bulk of the investigative stops did not play an important role in the crime reductions. The findings indicate that crime reduction can be achieved with more focused investigative stops.

  19. Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling.

    Directory of Open Access Journals (Sweden)

    Yu-Jen Chao

    Full Text Available Cell survival from the arrested state can be a cause of the cancer recurrence. Transition from the arrest state to the growth state is highly regulated by mitochondrial activity, which is related to the lipid compositions of the mitochondrial membrane. Cardiolipin is a critical phospholipid for the mitochondrial integrity and functions. We examined the changes of cardiolipin species by LC-MS in the transition between cell cycle arrest and cell reviving in HT1080 fibrosarcoma cells. We have identified 41 cardiolipin species by MS/MS and semi-quantitated them to analyze the detailed changes of cardiolipin species. The mass spectra of cardiolipin with the same carbon number form an envelope, and the C64, C66, C68, C70 C72 and C74 envelopes in HT1080 cells show a normal distribution in the full scan mass spectrum. The cardiolipin quantity in a cell decreases while entering the cell cycle arrest, but maintains at a similar level through cell survival. While cells awakening from the arrested state and preparing itself for replication, the groups with short acyl chains, such as C64, C66 and C68 show a decrease of cardiolipin percentage, but the groups with long acyl chains, such as C70 and C72 display an increase of cardiolipin percentage. Interestingly, the trends of the cardiolipin species changes during the arresting state are completely opposite to cell growing state. Our results indicate that the cardiolipin species shift from the short chain to long chain cardiolipin during the transition from cell cycle arrest to cell progression.

  20. Experimental Investigation on a Novel Four-bed Adsorption Chiller

    Science.gov (United States)

    Ng, Kim Choon; Chua, Hui Tong; Wang, Jin Bao; Wang, Xiao Lin; Kashiwagi, Takao; Akisawa, Atsushi; Saha, Bidyut Baran

    A prototype multi-bed regenerative adsorption chiller with a novel four-bed operation mode has been designed, fabricated and tested. The rating tests are conducted under assorted ARI coolant, using a purpose-built rating. The 4.bed design exhibits superior heat extraction capability from the heat source as its "slave-first-then-master" arrangement permits individual bed to maximize energy utilization in a batch cycle. Overall system performance of chiller is evaluated for various adsorption-desorption cycle and switching time at assorted coolant inlet temperatures. For fair comparison, the 4-bed chiller is also compared with that of a two-bed mode at the same working conditions.

  1. 3-D capacitance density imaging of fluidized bed

    Science.gov (United States)

    Fasching, George E.

    1990-01-01

    A three-dimensional capacitance density imaging of a gasified bed or the like in a containment vessel is achieved using a plurality of electrodes provided circumferentially about the bed in levels and along the bed in channels. The electrodes are individually and selectively excited electrically at each level to produce a plurality of current flux field patterns generated in the bed at each level. The current flux field patterns are suitably sensed and a density pattern of the bed at each level determined. By combining the determined density patterns at each level, a three-dimensional density image of the bed is achieved.

  2. Internal dust recirculation system for a fluidized bed heat exchanger

    Science.gov (United States)

    Gamble, Robert L.; Garcia-Mallol, Juan A.

    1981-01-01

    A fluidized bed heat exchanger in which air is passed through a bed of particulate material containing fuel disposed in a housing. A steam/water natural circulation system is provided in a heat exchange relation to the bed and includes a steam drum disposed adjacent the bed and a tube bank extending between the steam drum and a water drum. The tube bank is located in the path of the effluent gases exiting from the bed and a baffle system is provided to separate the solid particulate matter from the effluent gases. The particulate matter is collected and injected back into the fluidized bed.

  3. Fluidized bed heat exchanger utilizing angularly extending heat exchange tubes

    Science.gov (United States)

    Talmud, Fred M.; Garcia-Mallol, Juan-Antonio

    1980-01-01

    A fluidized bed heat exchanger in which air is passed through a bed of particulate material containing fuel disposed in a housing. A steam/water natural circulation system is provided and includes a steam drum disposed adjacent the fluidized bed and a series of tubes connected at one end to the steam drum. A portion of the tubes are connected to a water drum and in the path of the air and the gaseous products of combustion exiting from the bed. Another portion of the tubes pass through the bed and extend at an angle to the upper surface of the bed.

  4. The Principle of Proportionality and the European Arrest Warrant

    Directory of Open Access Journals (Sweden)

    Sarah Haggenmüller

    2013-01-01

    Full Text Available The European Arrest Warrant (EAW is a grossly coercive instrument that was designed for the persecution of serious cross-border crimes. In recent years, however, Member States have increasingly reported cases in which EAWs have not been issued for serious, but rather for harmless and minor offences. This article analyses the reasons behind the disproportionate use of the EAW and outlines measures to alleviate the problem. Thereby, it claims that in current debates different categories of disproportionate use of EAWs are often lumped together, and only concentrate on the introduction of a (binding proportionality test, failing to consider other alternative legislative solutions regarding minor crimes, such as the introduction of new comparable and effective alternative measures. These, however, are considered to be crucial for an alleviation of disproportionate warrants. La orden de detención europea (ODE es un instrumento extremadamente coercitivo que fue diseñado para la persecución de delitos transfronterizos graves. En años recientes, sin embargo, los Estados miembro han notificado cada vez más casos en los que la ODE no se debía a delitos serios, sino a casos menores e inofensivos.. En este artículo se analizan las razones que hay detrás del uso desproporcionado de la orden de detención europea y propone medidas para paliar el problema. De esta manera, se defiende que el debate actual, frecuentemente agrupan diferentes categorías de uso desproporcionado de la ODE, y sólo se concentran en la introducción de un test de proporcionalidad (vinculante, sin tener en cuenta otras soluciones legislativas alternativas, en lo que respecta a delitos menores, como la introducción de nuevas medidas alternativas, comparables y eficaces. Sin embargo, se considera que estas medidas son cruciales para reducir las órdenes de arresto desproporcionadas. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2200874

  5. Control of fluidized bed tea drying

    NARCIS (Netherlands)

    Temple, S.J.

    2000-01-01

    Tea is a product made from the leaf of the tea bush by several processes, including drying. The drying stage is the most energy intensive, and has tight performance criteria. This project investigated the options for the control of a fluidized bed tea dryer. The work included establishing some of th

  6. Agglomeration in fluidized beds: detection and counteraction

    NARCIS (Netherlands)

    Bartels. M.

    2008-01-01

    Fluidized beds comprise a quantity of solid particles that is suspended by an upward flowing gas. They are used for a variety of processes in the chemical industry, such as catalytic reactions, drying, coating and energy conversion. A major problem in industrial practice is the occurrence of unwante

  7. Exercise Training During Bed Rest Attenuates Deconditioning

    Science.gov (United States)

    Greenleaf, J. E.; Hargens, Alan R. (Technical Monitor)

    1995-01-01

    A 30-day 6 deg. head-down bed rest study was conducted to evaluate high-intensity, short-duration, alternating isotonic cycle ergometer exercise (ITE) training and high-intensity intermittent isokinetic exercise (IKE) training regiments designed to maintain peak VO2 and muscle mass, strength, and endurance at ambulatory control levels throughout prolonged bed rest. Other elements of the deconditioning (acclimation) syndrome, such as proprioception, psychological performance, hypovolemia, water balance, body composition, and orthostatic tolerance, were also measured. Compared with response during bed rest of the no exercise (NOE) control group: the ITE training regimen (a) maintained work capacity (peak VO2), (b) maintained plasma and red cell volume, (c) induced positive body water balance, (d) decreased quality of sleep and mental concentration, and (e) had no effect on the decrease in orthostatic tolerance; the IKE training regimen (a) attenuated the decrease in peak VO2 by 50%, (b) attenuated loss of red cell volume by 40%, but had no effect on loss of plasma volume, (c) induced positive body water balance, (d) had no adverse effect on quality of sleep or concentration, and (e) had no effect on the decrease in orthostatic tolerance. These findings suggest that various elements of the deconditioning syndrome can be manipulated by duration and intensity of ITE or IKE training regiments, and that several different training protocols will be required to maintain or restore physiological and psychological performance of individuals confined to prolonged bed rest.

  8. River Bed Sediment Classification Using ADCP

    Science.gov (United States)

    Description of physical aquatic habitat in rivers often includes data describing distributions of water depth, velocity and bed material type. Water depth and velocity in streams deeper than about 1 m may be continuously mapped using an acoustic Doppler current profiler from a moving boat. Herein ...

  9. A curved flume bed-load experiment

    NARCIS (Netherlands)

    Talmon, A.M.; Marsman, E.R.A.

    1988-01-01

    In this report the results of a bed-load experiment in a curved flume are presented. The experiments have been carried out in the Laboratory of Fluid Mechanics (L.F.M.) at the Delft University of Technology. The main object of the experiments is to develop and to test data-acquisition procedures for

  10. Effects Of Exercise During Prolonged Bed Rest

    Science.gov (United States)

    Arnaud, S.; Berry, P; Cohen, M.; Danelis, J.; Deroshia, C.; Greenleaf, J.; Harris, B.; Keil, L.; Bernauer, E.; Bond, M.; Ellis, S.; Lee, P.; Selzer, R.; Wade, C.

    1992-01-01

    Report describes experiment to investigate effects of isotonic and isokinetic leg exercises in counteracting effects of bed rest upon physical and mental conditions of subjects. Data taken on capacity for work, endurance and strength, tolerance to sitting up, equilibrium, posture, gait, atrophy, mineralization and density of bones, endocrine analyses concerning vasoactivity and fluid and electrolyte balances, intermediary metabolism of muscles, mood, and performance.

  11. Effect of Multiple Lightning Strikes on .the Performance of ZnOLightning Arrester Block%Effect of Multiple Lightning Strikes on .the Performance of ZnOLightning Arrester Block

    Institute of Scientific and Technical Information of China (English)

    Haryono T; Sirait K T; Tumiran; Hamzah Berahim

    2011-01-01

    A lightning arrester is used for electrical equipment protection against damage due to lightning strikes. One example of protected electrical equipment is electrical power transformer. If there is no lightning arrester installed to the transformer, when a lightning strike happens, it may receive a very high lightning overvoltage, which is certainly resulted in the transformer damage at its insulation. Usually, a lightning arrester specification data attached to a light- ning arrester contains the rating data of the lightning arrester current and voltage. In the use of lightning arrester, the possibility of receiving multiple lightning strikes is not taken into account sometimes. In fact, in some places, the number of multiple strikes in short duration is quiet high in number. This condition makes the lightning arrester being stroked by multiple lightning strikes. Therefore, it may change the lightning arrester's properties, and then the arrester may not be able to provide good electrical equipment protection against lightning strike anymore. This condition will result in great loss to electrical companies and electrical consumers. Therefore, this research studied the effect of applying multiple lightning strikes to ZnO lightning arrester block. Every time a group of lightning impulse current is applied to the ZnO lightning arrester block, it is followed by the measuring of its 50 Hz voltage and current characteristic. The changing in the ZnO lightning arrester block 50 Hz characteristic then can be analyzed. It was found that by applying more numbers of lightning strikes which made the arrester becoming worse, even though, actually, the lightning impulse peak current was still under the rating of the lightning arrester current. In this ease for a 5 kA, 24 kV lightning arrester, even though the lightning impulse peak current flowing through the ZnO lightning arrester block was still 2500 A, the lightning arrester ZnO block had already been damaged. Having been

  12. Updated Performance Evaluation of the ISS Water Processor Multifiltration Beds

    Science.gov (United States)

    Bowman, Elizabeth M.; Carter, Layne; Carpenter, Joyce; Orozco, Nicole; Weir, Natalee; Wilson, Mark

    2014-01-01

    The ISS Water Processor Assembly (WPA) produces potable water from a waste stream containing humidity condensate and urine distillate. The primary treatment process is achieved in the Multifiltration Beds, which include adsorbent media and ion exchange resin for the removal of dissolved organic and inorganic contaminants. Two Multifiltration Beds (MF Beds) were replaced on ISS in July 2010 after initial indication of inorganic breakthrough of the first bed and an increasing Total Organic Carbon (TOC) trend in the product water. The first bed was sampled and analyzed Sept 2011 through March 2012. The second MF Bed was sampled and analyzed June 2012 through August 2012. The water resident in the both beds was analyzed for various parameters to evaluate adsorbent loading, performance of the ion exchange resin, microbial activity, and generation of leachates from the ion exchange resin. Portions of the adsorbent media and ion exchange resin were sampled and subsequently desorbed to identify the primary contaminants removed at various points in the bed in addition to microbial analysis. Analysis of the second bed will be compared to results from the first bed to provide a comprehensive overview of how the Multifiltration Beds function on orbit. New data from the second bed supplements the analysis of the first bed (previously reported) and gives a more complete picture of breakthrough compounds, resin breakdown products, microbial activity, and difficult to remove compounds. The results of these investigations and implications to the operation of the WPA on ISS are documented in this paper.

  13. Pulse Detonation Engine Test Bed Developed

    Science.gov (United States)

    Breisacher, Kevin J.

    2002-01-01

    A detonation is a supersonic combustion wave. A Pulse Detonation Engine (PDE) repetitively creates a series of detonation waves to take advantage of rapid burning and high peak pressures to efficiently produce thrust. NASA Glenn Research Center's Combustion Branch has developed a PDE test bed that can reproduce the operating conditions that might be encountered in an actual engine. It allows the rapid and cost-efficient evaluation of the technical issues and technologies associated with these engines. The test bed is modular in design. It consists of various length sections of both 2- and 2.6- in. internal-diameter combustor tubes. These tubes can be bolted together to create a variety of combustor configurations. A series of bosses allow instrumentation to be inserted on the tubes. Dynamic pressure sensors and heat flux gauges have been used to characterize the performance of the test bed. The PDE test bed is designed to utilize an existing calorimeter (for heat load measurement) and windowed (for optical access) combustor sections. It uses hydrogen as the fuel, and oxygen and nitrogen are mixed to simulate air. An electronic controller is used to open the hydrogen and air valves (or a continuous flow of air is used) and to fire the spark at the appropriate times. Scheduled tests on the test bed include an evaluation of the pumping ability of the train of detonation waves for use in an ejector and an evaluation of the pollutants formed in a PDE combustor. Glenn's Combustion Branch uses the National Combustor Code (NCC) to perform numerical analyses of PDE's as well as to evaluate alternative detonative combustion devices. Pulse Detonation Engine testbed.

  14. Potential for the G2/M arrest assay to predict patient susceptibility to severe reactions following radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Perez, A.; Grabenbauer, G.G.; Sauer, R.; Distel, L.V.R. [Dept. of Radiation Oncology, Friedrich Alexander Univ. Erlangen-Nuremberg (Germany); Sprung, C.N. [Div. of Research, Peter MacCallum Cancer Centre, and Dept. of Biochemistry and Molecular Biology, Melbourne Univ., VIC (Australia)

    2007-02-15

    Background and purpose: cell-cycle regulation and checkpoint activation are crucial factors for radiation-induced DNA damage processing. The G2/M phase arrest was assessed in lymphoblastoid cell lines and phytohemagglutinin-stimulated T-lymphocytes of different radiosensitivities to study the relationship of G2/M arrest to radiosensitivity. Material and methods: G2/M arrest was analyzed after in vitro irradiation by 2 and 5 Gy of ionizing radiation up to 6 days using 17 lymphoblastoid cell lines from healthy individuals, ataxia-telangiectasia (AT) patients, Nijmegen breakage syndrome (NBS) patients and cancer patients with clinically increased radiosensitivity. In a second approach, phytohemagglutinin-stimulated T-lymphocytes from 15 healthy individuals, twelve cancer patients, and five cancer patients hypersensitive to ionizing radiation were studied. Image cytometry was performed to analyze G2/M arrest. Results: two of the three AT cell lines showed markedly increased G2/M arrest compared to controls. NBS cells were comparable to controls up to day 3, but then demonstrated a slightly increased G2/M arrest. Two of the six radiosensitive lymphoblast cell lines and the five radiosensitive cancer patients' T-lymphocytes assayed showed a reduction in G2/M arrest, while healthy individuals showed no difference from cancer patients. Conclusion: the interrelation between G2/M arrest and radiosensitivity is not readily apparent since a variety of radiosensitive cells from patients with radiosensitive syndromes and patients identified as radiosensitive following radiation treatment showed inconsistent G2/M arrest dynamics. Secondary effects, like loss of clonogenicity, G1/S phase arrest and failure of G2/M arrest may contribute to variation of the G2/M arrest endpoint and obscure assessment of cellular radiosensitivity using this method. (orig.)

  15. A METHOD OF DETERMINING THE ABILITY OF THE ARRESTER TO ABSORB ENERGY WITHOUT BREAKING THE HEAT BALANCE

    Directory of Open Access Journals (Sweden)

    S.Yu. Shevchenko

    2015-08-01

    Full Text Available Purpose.The aim of this study is to obtain a method for determining the capacity surge arrester nonlinear absorb energy without breaking the heat balance in modes of long-term application of operating voltage, which allows for analysis of their work in terms of violations as electricity. Methodology. For values of the energy passing through the arrester must be able to determine the current value for the voltage value in the area of leakage current-voltage characteristics. We have carried out calculations of the energy passing everywhere arrester for certain periods of time based on the current-voltage characteristics obtained experimentally. Analysis of the experimental current-voltage characteristics of resistors and literature led to the important conclusion that the dielectric properties of the ceramic varistor affect the value of active power losses in the arrester only when the active component of the leakage current is very small. This is confirmed by the characteristics of different classes of varistor voltage. This property of varistors and surge arresters shows the need to consider how the dielectric and conductive properties of the varistor ceramics in the analysis of work in the area of the arrester leakage current-voltage characteristic. These results demonstrate the need to clarify the mathematical model and the method for determining the energy dissipates in the area of the arrester leakage current CVC with their account. Results. The study, an improved mathematical model for calculating energy affects surge arrester during its working life. The study obtained the method, of evaluation capacity surge arrester, maintains heat balance throughout working life. Based on experimentally obtained current-voltage characteristic of the varistors is defined voltage at which surge arrester starts conducting active current. This allowed to receive specified mathematical model for calculating energy affects surge arrester and develop a method

  16. DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

    OpenAIRE

    Marangos, P; Stevense, M.; Niaka, K.; Lagoudaki, M.; Nabti, I.; Jessberger, R.; Carroll, J.

    2015-01-01

    In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to infertility and developmental disorders. However, there is little known about the response of oocytes to DNA damage. Here we find that oocytes with DNA damage arrest at metaphase of the first meiosis (MI). The MI arrest is induced by the spindle assembly checkpoint (SAC) because inhibiting the SAC overrides the DNA damage-induced MI arrest. Furthermore, this MI checkpoint is compromised in oocytes fro...

  17. Smoking marijuana in public: the spatial and policy shift in New York City arrests, 1992–2003

    OpenAIRE

    Golub Andrew; Johnson Bruce D; Dunlap Eloise

    2006-01-01

    Abstract Background During the 1990s, the New York Police Department (NYPD) greatly expanded arrests for smoking marijuana in public view (MPV). By 2000, MPV accounted for 15% of all arrests. The NYPD's supporters report this arrest activity is just part of quality-of-life (QOL) policing, which seeks to promote order in public locations by aggressively patrolling for behaviors that offend the general population. The NYPD's critics contend the NYPD has disproportionately targeted poor, black a...

  18. Structural Characterization of RNA Polymerase II Complexes Arrested by a Cyclobutane Pyrimidine Dimer in the Transcribed Strand of Template DNA*

    OpenAIRE

    Tornaletti, Silvia; Reines, Daniel; Hanawalt, Philip C.

    1999-01-01

    We have characterized the properties of immunopurified transcription complexes arrested at a specifically located cyclobutane pyrimidine dimer (CPD) using enzymatic probes and an in vitro transcription system with purified RNA polymerase II (RNAP II) and initiation factors. To help understand how RNAP II distinguishes between a natural impediment and a lesion in the DNA to initiate a repair event, we have compared the conformation of RNAP II complexes arrested at a CPD with complexes arrested...

  19. Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthood.

    Directory of Open Access Journals (Sweden)

    John Paul Wright

    2008-05-01

    Full Text Available BACKGROUND: Childhood lead exposure is a purported risk factor for antisocial behavior, but prior studies either relied on indirect measures of exposure or did not follow participants into adulthood to examine the relationship between lead exposure and criminal activity in young adults. The objective of this study was to determine if prenatal and childhood blood lead concentrations are associated with arrests for criminal offenses. METHODS AND FINDINGS: Pregnant women were recruited from four prenatal clinics in Cincinnati, Ohio if they resided in areas of the city with a high concentration of older, lead-contaminated housing. We studied 250 individuals, 19 to 24 y of age, out of 376 children who were recruited at birth between 1979 and 1984. Prenatal maternal blood lead concentrations were measured during the first or early second trimester of pregnancy. Childhood blood lead concentrations were measured on a quarterly and biannual basis through 6.5 y. Study participants were examined at an inner-city pediatric clinic and the Cincinnati Children's Hospital Medical Center in Cincinnati, Ohio. Total arrests and arrests for offenses involving violence were collected from official Hamilton County, Ohio criminal justice records. Main outcomes were the covariate-adjusted rate ratios (RR for total arrests and arrests for violent crimes associated with each 5 microg/dl (0.24 micromol/l increase in blood lead concentration. Adjusted total arrest rates were greater for each 5 microg/dl (0.24 micromol/l increase in blood lead concentration: RR = 1.40 (95% confidence interval [CI] 1.07-1.85 for prenatal blood lead, 1.07 (95% CI 0.88-1.29 for average childhood blood lead, and 1.27 (95% CI 1.03-1.57 for 6-year blood lead. Adjusted arrest rates for violent crimes were also greater for each 5 microg/dl increase in blood lead: RR = 1.34 (95% CI 0.88-2.03 for prenatal blood lead, 1.30 (95% CI 1.03-1.64 for average childhood blood lead, and 1.48 (95% CI 1

  20. Centerline Bed Elevation Profile of Sand Bed Channel due to Bar Formation

    Science.gov (United States)

    Tholibon, D. A.; Ariffin, J.; Abdullah, J.; Muhamad, N. S.

    2016-07-01

    Numerous data on bar formation have been accumulated yet the methods to predict bar geometry especially bar height are still insufficient. Objectives of this study to determine the trend in term of a significant difference of centreline bed elevation profile along the longitudinal distance. This can be investigate by carried out an experimental work in an erodible sand bed channel using a large-scale physical river model. The study included the various hydraulic characteristics with steady flow rates and sediment supply. An experimental work consists of four matrices of flow rate and channel width with other variables namely grains size and bed slope were kept constant. Analysis have included the discussion on a significant difference of centreline bed elevation profile along the longitudinal distance. As a conclusion the higher velocity in the smaller channel width have induced erosion of the banks that resulted in elevation increase while the larger flow rates have contributed to higher elevation.

  1. EXPERIMENTAL RESEARCH OF CYLINDER-TO-BED HEAT TRANSFER IN AGITATED FLUIDIZED BEDS

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Cylinder-to-bed heat transfer in agitated fluidized beds was studied experimentally.In the experiments, the aluminum particles were used as bed material, the diameter of which ranges from 0.5mm to 2mm.The effects of gas velocity, particles size, and agitator rotary speed on heat transfer were studied.From the experimental results, we have come to the following conclusions: (1) There are optimal ranges for airflow velocity and rotary speed to get optimal heat transfer coefficient; (2) The cylinder-to-bed heat transfer is greatly affected by gas velocity, rotary speed and particles sizes and the effect of rotary speed on heat transfer is similar to that of gas velocity; (3) Higher heat transfer coefficient is obtained with smaller particles.

  2. Fluctuations and time scales for bed-load sediment motion over a smooth bed

    Institute of Scientific and Technical Information of China (English)

    Francesco Ballio n; Alessio Radice

    2015-01-01

    Results are presented for experiments of bed-load sediment transport over a plane, smooth bed. The smooth-bed configuration, though not adequate for mimicking natural streams, enables the effects of bed roughness to be filtered out, thus, highlighting the role of flow turbulence for particle dynamics. Sediments were individually tracked along their paths, measuring position and velocity of the individual grains. A number of analyses were then applied to the data: probability density function, auto-correla-tion, and spectra of the grain velocity. Several Lagrangian time scales of particle motion were obtained and compared to available data for the turbulent flow field to determine a phenomenological inter-pretation of the process.

  3. STUDY ON SURGE ARRESTER PERFORMANCE DUE TO LIGHTNING STROKE IN 20 KV DISTRIBUTION LINES

    Directory of Open Access Journals (Sweden)

    Agung Warsito

    2012-02-01

    Full Text Available Electric energy has been transmiting from power station to end user with transmission and distribution lines.Lightning strokes are problems that occure in transmission and distribution lines and make them fault when theelectric energy were transmited. Surge Diverter or Lightning Arrester has been installing to reduce these faults.In this paper the simulation of lightning stroke and lightning arrester performance on distribution lines 20 kVwere done using EMTP (Electromagnetic Transient Program. Some parameters such us impuls voltage andincreasing voltage on distribution line was inverstigated. As case study in this simulation, Mojosongo 1 mainfeeder 20 kV three phase lines were used.The simulation results show that the lightning stroke 20 kA in By1-61-61E-84-9I on S phase at 0,1 ms, makevoltage on S phase was increased about 1,3054 MV. For R phase and T phase will increase of induced voltagewere 0.79539 MV and 0.80484 MV. We also show the performance of MOV Arrester (Metal Oxide Varistor inovercoming lightning stroke trouble, where arrester can decrease voltage up to 15.198 kV on S phase, while atR phase and T phase arrester can decrease voltage up to 11.375 kV and 13.616 kV.

  4. A novel parameter estimation method for metal oxide surge arrester models

    Indian Academy of Sciences (India)

    Mehdi Nafar; Gevork B Gharehpetian; Taher Niknam

    2011-12-01

    Accurate modelling and exact determination of Metal Oxide (MO) surge arrester parameters are very important for arrester allocation, insulation coordination studies and systems reliability calculations. In this paper, a new technique, which is the combination of Adaptive Particle Swarm Optimization (APSO) and Ant Colony Optimization (ACO) algorithms and linking the MATLAB and EMTP, is proposed to estimate the parameters of MO surge arrester models. The proposed algorithm is named Modified Adaptive Particle Swarm Optimization (MAPSO). In the proposed algorithm, to overcome the drawback of the PSO algorithm (convergence to local optima), the inertia weight is tuned by using fuzzy rules and the cognitive and the social parameters are self-adaptively adjusted. Also, to improve the global search capability and prevent the convergence to local minima, ACO algorithm is combined to the proposed APSO algorithm. The transient models of MO surge arrester have been simulated by using ATP-EMTP. The results of simulations have been applied to the program, which is based on MAPSO algorithm and can determine the fitness and parameters of different models. The validity and the accuracy of estimated parameters of surge arrester models are assessed by comparing the predicted residual voltage with experimental results.

  5. Effective Installations Technique of Grounding Conductors for Metal Oxide Surge Arresters

    Energy Technology Data Exchange (ETDEWEB)

    Lee, B.H.; Kang, S.M. [Inha University, Inchon (Korea); Ryu, I.S. [Korea Electric Power Corporation, Seoul (Korea)

    2002-06-01

    This paper deals with the effects of grounding conductors for metal oxide surge arresters. When surge arresters are improperly installed, the results can cause costly damage of electrical equipments. In particular, the route of surge arrester connection is very important because bends and links of leads increase the impedances to lightning surges and tend to nullify the effectiveness of a grounding conductor. Therefore, there is a need to know how effective installation of lightning surge arresters is made in order to control voltage and to absorb energy at high lightning currents. The effectiveness of a grounding conductor and 18 [kV] metal oxide distribution line arresters was experimentally investigated under the lightning and oscillatory impulse voltages. Thus, the results are as follows; (1) The induced voltage of a grounding conductor is drastically not affected by length of a connecting line, but it is very sensitive to types of grounding conductor. (2) The coaxial cable having a low characteristic impedance is suitable as a grounding conductor. (3) It is also clear from these results that bonding the metal raceway enclosing the grounding conductor to the grounding electrode is very effective because of skin effect. (4) The induced voltages of grounding conductors for the oscillatory impulse voltages are approximately twice as large as those for the lightning impulse voltages. (author). 9 refs., 12 figs., 2 tabs.

  6. A novel program focused on women survivors who were enrolled in a cardiac arrest pathway.

    Science.gov (United States)

    Herzog, Eyal; Tamis, Jacqueline; Aziz, Emad F; Shapiro, Janet M

    2013-03-01

    The number of cases of out-of-hospital cardiac arrest is estimated to be 300,000/year in the United States. Two landmark studies published in 2002 demonstrated that therapeutic hypothermia decreased mortality and improved neurological outcome after out-of-hospital cardiac arrest. Our institutional pathway for the management of survivors of cardiac arrest stresses teamwork involving multiple disciplines, including cardiology, critical care, nursing, neurology, infectious diseases, physical therapy, social work, and pastoral care. Involvement of the patients' families is critical in the understanding of the process and in the decision making and goals of care when neurological prognosis is poor. In a unique approach, we have included the survivors in the process. Our approach to quality improvement includes a yearly conference incorporating the voices of survivors and families. This conference serves as a means to review our experience, educate clinicians, involve all healthcare providers in the outcome, and provide a model of communication and professionalism to trainees. During review of our experience, we noted the small number of women undergoing therapeutic hypothermia, accounting for only 21% of all patients undergoing this therapy after cardiac arrest. This led to a conference that focused on cardiac disease and cardiac arrest in women.

  7. Abnormal mitosis triggers p53-dependent cell cycle arrest in human tetraploid cells.

    Science.gov (United States)

    Kuffer, Christian; Kuznetsova, Anastasia Yurievna; Storchová, Zuzana

    2013-08-01

    Erroneously arising tetraploid mammalian cells are chromosomally instable and may facilitate cell transformation. An increasing body of evidence shows that the propagation of mammalian tetraploid cells is limited by a p53-dependent arrest. The trigger of this arrest has not been identified so far. Here we show by live cell imaging of tetraploid cells generated by an induced cytokinesis failure that most tetraploids arrest and die in a p53-dependent manner after the first tetraploid mitosis. Furthermore, we found that the main trigger is a mitotic defect, in particular, chromosome missegregation during bipolar mitosis or spindle multipolarity. Both a transient multipolar spindle followed by efficient clustering in anaphase as well as a multipolar spindle followed by multipolar mitosis inhibited subsequent proliferation to a similar degree. We found that the tetraploid cells did not accumulate double-strand breaks that could cause the cell cycle arrest after tetraploid mitosis. In contrast, tetraploid cells showed increased levels of oxidative DNA damage coinciding with the p53 activation. To further elucidate the pathways involved in the proliferation control of tetraploid cells, we knocked down specific kinases that had been previously linked to the cell cycle arrest and p53 phosphorylation. Our results suggest that the checkpoint kinase ATM phosphorylates p53 in tetraploid cells after abnormal mitosis and thus contributes to proliferation control of human aberrantly arising tetraploids.

  8. Dimensional study of the dynamical arrest in a random Lorentz gas.

    Science.gov (United States)

    Jin, Yuliang; Charbonneau, Patrick

    2015-04-01

    The random Lorentz gas (RLG) is a minimal model for transport in heterogeneous media. Upon increasing the obstacle density, it exhibits a growing subdiffusive transport regime and then a dynamical arrest. Here, we study the dimensional dependence of the dynamical arrest, which can be mapped onto the void percolation transition for Poisson-distributed point obstacles. We numerically determine the arrest in dimensions d=2-6. Comparison of the results with standard mode-coupling theory reveals that the dynamical theory prediction grows increasingly worse with d. In an effort to clarify the origin of this discrepancy, we relate the dynamical arrest in the RLG to the dynamic glass transition of the infinite-range Mari-Kurchan-model glass former. Through a mixed static and dynamical analysis, we then extract an improved dimensional scaling form as well as a geometrical upper bound for the arrest. The results suggest that understanding the asymptotic behavior of the random Lorentz gas may be key to surmounting fundamental difficulties with the mode-coupling theory of glasses. PMID:25974497

  9. Arrester installations for improving the lightning performance of double circuits distribution lines

    Energy Technology Data Exchange (ETDEWEB)

    Thanasaksiri, T. [ChiangMai Univ., ChianMai (Thailand). Dept. of Electrical Engineering

    2007-07-01

    The Provincial Electricity Authority (PEA) of Thailand serves 99 per cent of the the country's power customers. The main power distribution lines used by PEA consist of 22 and 33 kV high voltage distribution systems and a 400/230 V low voltage system. In order to supply more energy and for economic reasons, distribution lines for industrial and commercial loads consist of double circuits. Lightning strikes on either circuit can affect the other. There are different methods that can be used to reduce the number of flashovers on lines and improve the lightning performance of lines. This paper presented a method for improving the lightning performance of 22 kV double circuit overhead distribution lines by means of arrester installations. The study focused both on partial and full arrester installations and considered arrester energy discharge. The paper discussed the electromagnetic transients program (EMTP) model of systems studied, including a pole and footing impedance model; a line model; an arrester model; an insulator model; a flashover model; and a lightning source model. The studied configurations included pole structure types; phase and ground wire conductors; lightning arresters; insulators; and ground rods. It was concluded that full installation provides better lightning performance compared to partial installation. 7 refs., 8 tabs.

  10. Management of survivors of cardiac arrest - the importance of genetic investigation.

    Science.gov (United States)

    Schwartz, Peter J; Dagradi, Federica

    2016-09-01

    Management of survivors of cardiac arrest is largely based on a traditional approach. However, during the past decade, arrhythmias of genetic origin have increasingly been recognized as contributing to many more cases than previously appreciated. This realization is forcing physicians managing the survivors of cardiac arrest also to consider family members. In this Perspectives article, we examine the appropriate management approaches for survivors of cardiac arrests related to channelopathies, cardiomyopathies, or ischaemic heart disease, and for their families. Important implications for families of individuals who have experienced sudden cardiac death as part of sudden infant death syndrome or during sport activity are also discussed. Congenital long QT syndrome provides a paradigm of the logical sequence of the steps that should be performed. When a diagnosis of the cause of the cardiac arrest is certain or probable, every effort should be made to identify the genetic basis of disease, because this approach will enable the identification and early protection of similarly affected family members. Accordingly, the availability in hospitals of at least one cardiologist with cardiovascular genetics expertise would improve the management of survivors of cardiac arrest as well as of their families. PMID:27383078

  11. [Ability of typical greenery shrubs of Beijing to adsorb and arrest PM2.5 ].

    Science.gov (United States)

    Liang, Dan; Wang, Bin; Wang, Yun-qi; Zhang, Hui-lan; Yang, Song-nan; Li, Ang

    2014-09-01

    Four typical types of green shrubs of Beijing (Euonymus japonicus, Buxus microphylla, Berberis thunbergii cv. atropurpurea, Taxus cuspidate cv. nana) were selected to study their capacities in adsorbing and arresting PM2.5 using both field observations and air chamber simulations. Concurrently, in order to analyze the pollution characteristics of Beijing in winter and spring, the PM2.5 concentrations of December 2012 to May 2013 were collected. Experimental results showed that: From the gas chamber experiments, the ability to adsorb and arrest PM2.5 was in the order of Berberis thunbergii cv. atropurpurea > Buxus microphylla > Taxus cuspidate cv. nana > Euonymus japonicus, mainly due to the differences in leaf characteristics; Outside measurement results showed that the ability to adsorb and arrest PM2.5 was ranked as Buxus microphylla > Berberis thunbergii cv. atropurpurea > Taxus cuspidate cv. nana > Euonymus japonicus. Chamber simulation and outdoor observation showed that Buxus microphylla and Berberis thunbergii cv. atropurpurea had strong ability to adsorb and arrest PM2.5; Meanwhile, the slight differences between the chamber simulation and outdoor observation results might be related to plant structure. Compared to tree species, the planting condition of shrub species was loose, and it greened quickly; By analyzing the Beijing PM2.5 concentration values in winter and spring, it was found that the PM2.5 concentration was particularly high in the winter of Beijing, and evergreen shrubs maintained the ability to adsorb and arrest PM2.5. PMID:25518685

  12. Main Complications of Mild Induced Hypothermia after Cardiac Arrest: A Review Article

    Directory of Open Access Journals (Sweden)

    Hassan Soleimanpour

    2014-03-01

    Full Text Available The aim of the present study is to assess the complications of mild induced hypothermia (MIH in patients with cardiac arrest. Presently, based on the guidelines of the American heart Association, MIH following successful cardiopulmonary resuscitation (CPR in unconscious adult patients due to ventricular fibrillation (VF with out-of-hospital cardiac arrest (OOHCA is essential and required. However, MIH could be associated with complications in Patients with cardiac arrest. Studies conducted on the precautions and care following cardiac arrest and MIH were included. Valid scientific data bases were used for data collection. The obtained results from different studies revealed that mild MIH could be associated with numerous complications and the knowledge and awareness of the medical staff from the complications is required to guarantee successful therapeutic approaches in MIH following cardiac arrest which is a novel medical facility with different styles and complications. Overall, further future studies are required to improve the quality of MIH, to increase survival and to decrease complications rates.

  13. Double Bolus Thrombolysis for Suspected Massive Pulmonary Embolism during Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Gerard O’Connor

    2015-01-01

    Full Text Available More than 70% of cardiac arrest cases are caused by acute myocardial infarction (AMI or pulmonary embolism (PE. Although thrombolytic therapy is a recognised therapy for both AMI and PE, its indiscriminate use is not routinely recommended during cardiopulmonary resuscitation (CPR. We present a case describing the successful use of double dose thrombolysis during cardiac arrest caused by pulmonary embolism. Notwithstanding the relative lack of high-level evidence, this case suggests a scenario in which recombinant tissue Plasminogen Activator (rtPA may be beneficial in cardiac arrest. In addition to the strong clinical suspicion of pulmonary embolism as the causative agent of the patient’s cardiac arrest, the extremely low end-tidal CO2 suggested a massive PE. The absence of dilatation of the right heart on subxiphoid ultrasound argued against the diagnosis of PE, but not conclusively so. In the context of the circulatory collapse induced by cardiac arrest, this aspect was relegated in terms of importance. The second dose of rtPA utilised in this case resulted in return of spontaneous circulation (ROSC and did not result in haemorrhage or an adverse effect.

  14. Double Bolus Thrombolysis for Suspected Massive Pulmonary Embolism during Cardiac Arrest.

    Science.gov (United States)

    O'Connor, Gerard; Fitzpatrick, Gareth; El-Gammal, Ayman; Gilligan, Peadar

    2015-01-01

    More than 70% of cardiac arrest cases are caused by acute myocardial infarction (AMI) or pulmonary embolism (PE). Although thrombolytic therapy is a recognised therapy for both AMI and PE, its indiscriminate use is not routinely recommended during cardiopulmonary resuscitation (CPR). We present a case describing the successful use of double dose thrombolysis during cardiac arrest caused by pulmonary embolism. Notwithstanding the relative lack of high-level evidence, this case suggests a scenario in which recombinant tissue Plasminogen Activator (rtPA) may be beneficial in cardiac arrest. In addition to the strong clinical suspicion of pulmonary embolism as the causative agent of the patient's cardiac arrest, the extremely low end-tidal CO2 suggested a massive PE. The absence of dilatation of the right heart on subxiphoid ultrasound argued against the diagnosis of PE, but not conclusively so. In the context of the circulatory collapse induced by cardiac arrest, this aspect was relegated in terms of importance. The second dose of rtPA utilised in this case resulted in return of spontaneous circulation (ROSC) and did not result in haemorrhage or an adverse effect. PMID:26664765

  15. Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution.

    Science.gov (United States)

    Masip, Martin E; Huebinger, Jan; Christmann, Jens; Sabet, Ola; Wehner, Frank; Konitsiotis, Antonios; Fuhr, Günther R; Bastiaens, Philippe I H

    2016-08-01

    The dynamics of molecules in living cells hampers precise imaging of molecular patterns by functional and super-resolution microscopy. We developed a method that circumvents lethal chemical fixation and allows on-stage cryo-arrest for consecutive imaging of molecular patterns within the same living, but arrested, cells. The reversibility of consecutive cryo-arrests was demonstrated by the high survival rate of different cell lines and by intact growth factor signaling that was not perturbed by stress response. Reversible cryo-arrest was applied to study the evolution of ligand-induced receptor tyrosine kinase activation at different scales. The nanoscale clustering of epidermal growth factor receptor (EGFR) in the plasma membrane was assessed by single-molecule localization microscopy, and endosomal microscale activity patterns of ephrin receptor A2 (EphA2) were assessed by fluorescence lifetime imaging microscopy. Reversible cryo-arrest allows the precise determination of molecular patterns while conserving the dynamic capabilities of living cells. PMID:27400419

  16. Measuring bed shear stress along vegetated river beds using FST-hemispheres.

    Science.gov (United States)

    Bockelmann-Evans, B N; Davies, R; Falconer, R A

    2008-09-01

    The measurement of the bed shear stress along vegetated river beds is essential for accurately predicting the water level, velocity and solute and sediment transport fluxes in computational hydroenvironmental models. Details are given herein of an experimental and theoretical study to determine the bed boundary shear stress along vegetated river beds introducing a novel field measuring method, namely the FliessWasserStammtisch (FST)-hemispheres. Although investigations have been conducted previously for sedimentary channels using the FST-hemispheres, this preliminary study is thought to be the first time that such hemispheres have been used to investigate the bed shear stresses in vegetated channels. FST-hemispheres were first developed by Statzner and Müller [1989. Standard hemispheres as indicators of flow characteristics in lotic benthos research. Freshwater Biology 21, 445-459] to act as an integrated indicator of the gross hydrodynamic stresses present near the bed. Test and validation data were found to be at least of the same order of magnitude for the stresses predicted from literature for sedimentary channels, with this study establishing the commencement of a database of calibrated FST-hemisphere laboratory data for vegetated channel beds. In a series of experiments, depths ranging from 0.1 to 0.28 m were considered, equating directly to comparable conditions in small rivers or streams. The results of this study provide a basis for enabling the FST-hemispheres to be used to evaluate the boundary shear stress for a wider range of applications in the future, including vegetated river beds.

  17. Comparison of packed bed and fluidized bed membrane reactors for methane reforming

    OpenAIRE

    Gallucci, Fausto; Sint Annaland, van, Martin; Kuipers, J.A.M.

    2009-01-01

    In this work the performance of different membrane reactor concepts, both fluidized bed and packed bed membrane reactors, have been compared for the reforming of methane for the production of ultra-pure hydrogen. Using detailed theoretical models, the required membrane area to reach a given conversion and the prevailing temperature profiles have been compared. The extent of mass and heat transfer limitations in the different reactors have been evaluated, and strategies to decrease (or avoid) ...

  18. Acute right ventricular myocardial injury and sudden cardiac arrest in a patient with persistent spontaneous coronary vasospasm

    Institute of Scientific and Technical Information of China (English)

    Hung Ming-Yow; Li Ju-Chi; Hao Wen-Rui; Wu Cheng-Hsueh; Hung Ming-Jui

    2011-01-01

    Coronary vasospasm is a rare diagnosis resulting in sudden arrhythmic cardiac arrest. We report a case of a healthy,non-smoking elderly woman resuscitated from arrhythmic cardiac arrest. She had persistent spontaneous coronaxy vasospasm, leading to right ventricular myocardial injury and failure, and shock. She responded quickly to intravenous normal saline bolus infusion, but had irreversible neurological sequelae. Additionally, she had atrial fibrillation preceding ischemic ventricular fibrillation, a rare finding in coronary vasospasm-related cardiac arrest. We suggest immediate coronary angiography of patients in sudden arrhythmic cardiac arrest with acute right ventricular failure for a prompt,accurate diagnosis and appropriate management of the coronary vasospasm.

  19. Protection against lightning surges provided by line arresters - Furnas' experience on 138 kV system

    Energy Technology Data Exchange (ETDEWEB)

    Camara, Alessandra S.B.; Esmeraldo, Paulo C.V.; Nigri, Armando [FURNAS Centrais Eletricas S.A., Rio de Janeiro, RJ (Brazil)

    1999-07-01

    Furnas is about to make use of the line surge arrester technology in its network, based on studies that have been developed regarding with line performance improvement. In association to such studies, Furnas has installed six line arresters units on a 138 kV line with an arrester manufacturer cooperation, in order to get some experience on installation and maintenance, besides lightning incidence monitoring and line arrester behavior analysis. This paper presents first results and conclusions related to this 138 kV experimental installation on Furnas system. (author)

  20. Prevention and Control of Bed Bugs in Residences

    Science.gov (United States)

    ... on a backpack Bed bugs along a mattress seam Bed bugs on the underside of a box ... Controlling an infestation requires very detailed work, much moving and disassembly of furniture, and specialty equipment. Careful ...

  1. Bed bugs (Cimex lectularius) as vectors of Trypanosoma cruzi.

    Science.gov (United States)

    Salazar, Renzo; Castillo-Neyra, Ricardo; Tustin, Aaron W; Borrini-Mayorí, Katty; Náquira, César; Levy, Michael Z

    2015-02-01

    Populations of the common bed bug, Cimex lectularius, have recently undergone explosive growth. Bed bugs share many important traits with triatomine insects, but it remains unclear whether these similarities include the ability to transmit Trypanosoma cruzi, the etiologic agent of Chagas disease. Here, we show efficient and bidirectional transmission of T. cruzi between hosts and bed bugs in a laboratory environment. Most bed bugs that fed on experimentally infected mice acquired the parasite. A majority of previously uninfected mice became infected after a period of cohabitation with exposed bed bugs. T. cruzi was also transmitted to mice after the feces of infected bed bugs were applied directly to broken host skin. Quantitative bed bug defecation measures were similar to those of important triatomine vectors. Our findings suggest that the common bed bug may be a competent vector of T. cruzi and could pose a risk for vector-borne transmission of Chagas disease. PMID:25404068

  2. Biomass ash - bed material interactions leading to agglomeration in fluidised bed combustion and gasification

    Energy Technology Data Exchange (ETDEWEB)

    Visser, H.J.M.; Hofmans, H.; Huijnen, R.; Kastelein, R.; Kiel, J.H.A. [ECN Biomass, Petten (Netherlands)

    2000-07-01

    The present study has been aimed at improving the fundamental understanding of mechanisms underlying agglomeration and defluidisation in fluidised bed combustion and gasification of biomass and waste. To this purpose dedicated lab-scale static heating and fluidisation experiments have been conducted with carefully selected and prepared ashes and bed materials, viz. straw ash/sand and willow ash/sand mixtures, mullite subjected to straw gasification and artificially coated mullite. The main conclusion is that ash/bed material interaction processes are very important and often determine the bed agglomeration and defluidisation tendency. In the static heating experiments with both ash/sand mixtures, partial melting-segregation of ash components and dissolution/reaction with the bed material are processes that determine the melt composition. This melt composition and behaviour can deviate considerably form expectations based on ash-only data. Artificially coated bed materials prove to be very useful for systematic studies on the influence of coating composition and thickness on agglomeration tendency. For the coated mullite samples, different stages in the defluidisation process are identified and the influence of coating properties (thickness, composition, morphology) and operating parameters is elucidated. The behaviour of the mullite appears to be dominated by a remnant glass phase. On the one hand, this glass phase accounts for an alkali-getter capability, while on the other hand it is mainly responsible for agglomeration at temperatures {>=} 800C. 3 refs.

  3. Deleterious Thermal Effects Due To Randomized Flow Paths in Pebble Bed, and Particle Bed Style Reactors

    Science.gov (United States)

    Moran, Robert P.

    2013-01-01

    A review of literature associated with Pebble Bed and Particle Bed reactor core research has revealed a systemic problem inherent to reactor core concepts which utilize randomized rather than structured coolant channel flow paths. For both the Pebble Bed and Particle Bed Reactor designs; case studies reveal that for indeterminate reasons, regions within the core would suffer from excessive heating leading to thermal runaway and localized fuel melting. A thermal Computational Fluid Dynamics model was utilized to verify that In both the Pebble Bed and Particle Bed Reactor concepts randomized coolant channel pathways combined with localized high temperature regions would work together to resist the flow of coolant diverting it away from where it is needed the most to cooler less resistive pathways where it is needed the least. In other words given the choice via randomized coolant pathways the reactor coolant will take the path of least resistance, and hot zones offer the highest resistance. Having identified the relationship between randomized coolant channel pathways and localized fuel melting it is now safe to assume that other reactor concepts that utilize randomized coolant pathways such as the foam core reactor are also susceptible to this phenomenon.

  4. Flow Pattern Identification of Fluidized Beds Using ECT

    Institute of Scientific and Technical Information of China (English)

    S. Liu; W.Q. Yang; H. Wang; G. Yan; Z. Pan

    2001-01-01

    Electrical capacitance tomography (ECT) was applied in measuring solids distribution in square circulating fluidized beds. The fluidization conditions varied from bubbling fluidized bed to circulating fluidized bed. In the whole range of fluidization conditions, ECT was able to instantaneously provide the solids concentration and voids distributions in the fluidized beds. According to the acquired data from ECT and reconstructed image,different fluidization regimes can also be identified.

  5. Model for the Evolving Bed Surface around an Offshore Monopile

    DEFF Research Database (Denmark)

    Hartvig, Peres Akrawi

    2012-01-01

    This paper presents a model for the bed surface around an offshore monopile. The model has been designed from measured laboratory bed surfaces and is shown to reproduce these satisfactorily for both scouring and backfilling. The local rate of the bed elevation is assumed to satisfy a certain...... general parametrized surface. The model also accounts for sliding of sediment particles when the angle of the local bed slope exceeds the angle of repose....

  6. Collecting aerosol in airflow with a magnetically stabilized fluidized bed

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A magnetically stabilized fluidized bed (MSB) is a highly efficient filter that takes the advantage of both fluidized beds and fixed beds. This paper presents the research to collect aerosol in airflow with a MSB. The filtering model of MSB is established with its parameters including magnetic field intensity,gas superficial velocity, average grain-size, and bed height on thecollection efficiency of MSB. The model is verified by experiments.

  7. Disturbances of sensation occasioned by experimental arrest of blood flow

    Directory of Open Access Journals (Sweden)

    Alfred Auersperg

    1949-12-01

    Full Text Available Disturbances of sensation in the hand were studied during and after experimental arrest of circulation to the arm. Blockage of circulation was performed as outlined by Lewis and Pochin, by putting the cuff of a sphygmomanometer on the upper arm and bringing the pressure rapidly up to 200 mm/Hg. The experiments listed below were intended to demonstrate the variability of a central reaction brought about by fairly definite disturbances of the ischaemic periphery. All experiments were made on the present writers and repeated on nine other subjects, none of whom had systolic pressure reaching 150 mm/Hg. I - Blockage of circulation in both arms led to symmetrical phenomena in both hands (thermal paresthesias, tingling and hyposthesia, both under symmetrical experimental circumstances, and under the following variations: So long as the cuff pressure on both arms was above the systolic blood pressure, differences as great as 300 mm/Hg in one cuff and 150 mm in the other did not alter the symmetry of the effects. Neither was symmetry and synchronism of paresthesias affected when compression on one side preceded equal compression on the other up to 20 seconds. II - When a punctate pressure is applied to the paresthetic field the paresthesias disappear around that point and the latter is clearly brought out from the indifferent background produced in the area of depressed skin. On the basis of Kugelberg's findings, it seems that this occurs because the impulses caused by pressure have a higher frequency and substitute the spontaneous abnormal discharges of the ischaemic nerve fibers. III - Repeated mechanical stimulation of a fingertip during the experiment failed to show any influence on sensory (touch thresholds, in contrast, therefore, to what would be expected on the basis of the physiologic experiments which show rapid fatigue of ischaemic structures. IV - In contrast to what might be expected from the intense changes undergone by receptors in the

  8. Fluidized Bed Asbestos Sampler Design and Testing

    Energy Technology Data Exchange (ETDEWEB)

    Karen E. Wright; Barry H. O' Brien

    2007-12-01

    A large number of samples are required to characterize a site contaminated with asbestos from previous mine or other industrial operations. Current methods, such as EPA Region 10’s glovebox method, or the Berman Elutriator method are time consuming and costly primarily because the equipment is difficult to decontaminate between samples. EPA desires a shorter and less costly method for characterizing soil samples for asbestos. The objective of this was to design and test a qualitative asbestos sampler that operates as a fluidized bed. The proposed sampler employs a conical spouted bed to vigorously mix the soil and separate fine particulate including asbestos fibers on filters. The filters are then analyzed using transmission electron microscopy for presence of asbestos. During initial testing of a glass prototype using ASTM 20/30 sand and clay fines as asbestos surrogates, fine particulate adhered to the sides of the glass vessel and the tubing to the collection filter – presumably due to static charge on the fine particulate. This limited the fines recovery to ~5% of the amount added to the sand surrogate. A second prototype was constructed of stainless steel, which improved fines recovery to about 10%. Fines recovery was increased to 15% by either humidifying the inlet air or introducing a voltage probe in the air space above the sample. Since this was not a substantial improvement, testing using the steel prototype proceeded without using these techniques. Final testing of the second prototype using asbestos suggests that the fluidized bed is considerably more sensitive than the Berman elutriator method. Using a sand/tremolite mixture with 0.005% tremolite, the Berman elutriator did not segregate any asbestos structures while the fluidized bed segregated an average of 11.7. The fluidized bed was also able to segregate structures in samples containing asbestos at a 0.0001% concentration, while the Berman elutriator method did not detect any fibers at this

  9. Experimental modelling of outburst flood - bed interactions

    Science.gov (United States)

    Carrivick, J. L.; Xie, Z.; Sleigh, A.; Hubbard, M.

    2009-04-01

    Outburst floods are a sudden release and advancing wave of water and sediment, with a peak discharge that is often several orders of magnitude greater than perennial flows. Common outburst floods from natural sources include those from glacial and moraine-impounded lakes, freshwater dyke and levee bursts, volcanic debris dams, landslides, avalanches, coastal bay-bars, and those from tree or vegetation dams. Outburst flood hazards are regularly incorporated into risk assessments for urban, coastal and mountainous areas, for example. Outburst flood hazards are primarily due to direct impacts, caused by a frontal surge wave, from debris within a flow body, and from the mass and consistency of the flows. A number of secondary impacts also pose hazards, including widespread deposition of sediment and blocked tributary streams. It is rapid landscape change, which is achieved the mobilization and redistribution of sediment that causes one of the greatest hazards due to outburst floods. The aim of this project is therefore to parameterise hydrodynamic - sedimentary interactions in experimental outburst floods. Specifically, this project applies laboratory flume modelling, which offers a hitherto untapped opportunity for examining complex interactions between water and sediment within outburst floods. The experimental set-up is of a tradition lock-gate design with a straight 4 m long tank. Hydraulics are scaled at 1:20 froude scale and the following controls on frontal wave flow-bed interactions and hence on rapid landscape change are being investigated: 1. Pre-existing mobile sediment effects, fixed bed roughness effects, sediment concentration effects, mobile bed effects. An emphasis is being maintained on examining the downstream temporal and spatial change in physical character of the water / sediment frontal wave. Facilities are state-of-the-art with a fully-automated laser bed-profiler to measure bed elevation after a run, Seatek arrays to measure transient flow

  10. Sudden Cardiac Arrest due to Brugada Syndrome: a Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    R Soleimanirad

    2013-04-01

    Full Text Available Brugada Syndrome is a rare cause of sudden cardiac arrest and has a unique ECG pattern. In fact, with ST-segment elevation down sloping in the right precordial leads (v1-v3, RBBB pattern in lateral leads and J-point elevation is revealed. We must notice and avoid trigger factors of this syndrome during general anesthesia. Patient is a 39 old man who attended to emergency department with sudden cardiac arrest and resuscitate. He was transferred to ICU for management of hypoxic ischemic encephalopathy. Complementary studies concluded the diagnosis of Brugada syndrome. We must consider Brugada syndrome within patients with family history of sudden cardiac arrest. Moreover, we must avoid trigger factors of this syndrome such as fever, bradicardia and electrolyte abnormality (specialy Na, Ca abnormalities during general anesthesia and if they appear, we should treat them.

  11. Arrested pneumatization of the sphenoid sinus mimicking intraosseous lesions of the skull base

    Energy Technology Data Exchange (ETDEWEB)

    Jalali, Elnaz; Tadinada, Aditya [Dept. of Oral and Maxillofacial Radiology, University of Connecticut School of Dental Medicine, Farmington (United States)

    2015-03-15

    Arrested pneumatization of the sphenoid sinus is a developmental variant that is not always well recognized and is often confused with other pathologies associated with the skull base. This report describes the case of a patient referred for cone-beam computed tomography (CBCT) imaging for dental implant therapy. CBCT demonstrated a well-defined incidental lesion in the left sphenoid sinus with soft tissue-like density and sclerotic borders with internal curvilinear opacifications. The differential diagnoses included intraosseous lipoma, arrested pneumatization of the sphenoid sinus, chondrosarcoma, chondroid chordoma, and ossifying fibroma. The radiographic diagnosis of arrested pneumatization was based on the location of the lesion, its well-defined nature, the presence of internal opacifications, and lack of expansion. Gray-scale CBCT imaging of the area demonstrated values similar to fatty tissue. This case highlighted the fact that benign developmental variants associated with the skull base share similar radiographic features with more serious pathological entities.

  12. Mandatory Arrest Law in domestic violence cases and its implementation in New York City

    Directory of Open Access Journals (Sweden)

    Milivojević Sanja K.

    2002-01-01

    Full Text Available This paper contains the analysis of the Mandatory Arrest Law in domestic violence cases in New York State. Introduction includes the subject and main goals of the paper. Second chapter starts with historical development of the police response in domestic violence cases in New York before and after the Mandatory Arrest Law is passed, than analysis of the Law, and ends with one of the programs which Safe Horizon, Victim Service organization, developed in New York City. Third chapter gives the analysis of pro et contra arguments for mandatory arrest provision and results of surveys and studies, which were conducted in United States. In fourth chapter we present the analysis of the research conducted in two police precincts in New York City this year. Paper also contains the list of main problems in implementation of this Law in New York City.

  13. Assessment of risks for employees of France Telecom regarding overvoltage arresters containing radio-elements

    International Nuclear Information System (INIS)

    As a great number of overvoltage arresters used by France Telecom to protect its telecommunication network against disturbing voltages (notably lightning) contain radio-elements, this report aims at assessing dose levels and associated risks for employees exposed to radioactive overvoltage arrester when setting them up, exploiting installations containing such arresters, or when removing them. After a presentation of these devices, a modelling of activities and geometries is proposed, as well as computation tools. Different scenarios and exposure situations are considered. As far as risks are concerned, after a recall on cancers and ionizing radiation, and on the exposure of France Telecom employees, the report comments the knowledge on radio-induced cancers; notably breast cancer, skin cancer, and mouth and pharynx cancers

  14. Barriers to recognition of out-of-hospital cardiac arrest during emergency medical calls

    DEFF Research Database (Denmark)

    Alfsen, David; Møller, Thea Palsgaard; Egerod, Ingrid;

    2015-01-01

    the dispatchers' recognition of OHCA, focusing on the communication during the emergency call. The purpose of this study is to identify factors affecting medical dispatchers' recognition of OHCA during emergency calls in a qualitative analysis of calls. METHODS: An investigator triangulated inductive thematic...... analysis of recordings of out-of-hospital cardiac arrest emergency calls from December 2012. Participants were the callers (bystanders) and the emergency medical dispatchers. Data were analysed using a hermeneutic approach. RESULTS: Based on the concept of data saturation, 13 recordings of not recognised...... cardiac arrest and 8 recordings of recognised cardiac arrests were analysed. Three main themes, six subthemes and an embedded theme emerged from the analysis: caller's physical distance (caller near patient, caller not near patient), caller's emotional distance (keeping calm, losing control), caller...

  15. Survival in patients without acute ST elevation after cardiac arrest and association with early coronary angiography

    DEFF Research Database (Denmark)

    Dankiewicz, J; Nielsen, N; Annborn, M;

    2015-01-01

    PURPOSE: To investigate whether early coronary angiography (CAG) after out-of-hospital cardiac arrest of a presumed cardiac cause is associated with improved outcomes in patients without acute ST elevation. METHODS: The target temperature management after out-of-hospital cardiac arrest (TTM) trial...... early CAG was not significantly associated with survival. CONCLUSIONS: In this post hoc observational study of a large randomized trial, early coronary angiography for patients without acute ST elevation after out-of-hospital cardiac arrest of a presumed cardiac cause was not associated with improved...... showed no difference in all-cause mortality or neurological outcome between an intervention of 33 and 36 °C. In this post hoc analysis, 544 patients where the admission electrocardiogram did not show acute ST elevation were included. Early CAG was defined as being performed on admission or within...

  16. Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest

    DEFF Research Database (Denmark)

    Nielsen, Niklas; Wetterslev, Jørn; Cronberg, Tobias;

    2013-01-01

    is unknown. Our objective was to compare two target temperatures, both intended to prevent fever. Methods In an international trial, we randomly assigned 950 unconscious adults after out-of-hospital cardiac arrest of presumed cardiac cause to targeted temperature management at either 33°C or 36°C...... (risk ratio, 1.01; 95% CI, 0.89 to 1.14; P=0.87). The results of analyses adjusted for known prognostic factors were similar. Conclusions In unconscious survivors of out-of-hospital cardiac arrest of presumed cardiac cause, hypothermia at a targeted temperature of 33°C did not confer a benefit......Background Unconscious survivors of out-of-hospital cardiac arrest have a high risk of death or poor neurologic function. Therapeutic hypothermia is recommended by international guidelines, but the supporting evidence is limited, and the target temperature associated with the best outcome...

  17. Identifying non-technical skills and barriers for improvement of teamwork in cardiac arrest teams

    DEFF Research Database (Denmark)

    Andersen, P.O.; Jensen, Michael Kammer; Lippert, A.;

    2010-01-01

    for improving team performance in multi-professional cardiac arrest teams, and to describe barriers to the use and implementation of such NTSs by using a qualitative method. Methods: Individual semi-structured interviews were conducted with 11 Danish Advanced Life Support instructors during the period April...... 2006 to November 2006. Interviews were focussed on barriers and recommendations for teamwork in the cardiac arrest team, optimal policy for improvement of resuscitation training and clinical practice, use of cognitive aids and adoption of European Resuscitation Council (ERC) Guidelines 2005. Interviews...... management. Important barriers that were identified were inexperienced team leaders, task overload and hierarchic structure in the teams' inability to maintain focus on chest compressions. Conclusion: Interview participants pointed out that NTSs of teams could improve the treatment of cardiac arrest...

  18. Evidence of kinetic arrest in Se doped CoS2

    Science.gov (United States)

    Mishra, Saroj Kumar; Rawat, R.

    2016-10-01

    Our systematic path dependent resistivity study in H-T space shows that paramagnetic (PM)-ferromagnetic (FM) transition in CoS1.76Se0.24 is kinetically arrested. The resistivity at low temperature depends on the path followed in H-T space and the critical field required for PM to FM transition varies non-monotonically with temperature. Measurements under CHUF (cooling and heating in unequal magnetic field) protocol show reentrant transition on warming under higher magnetic field (than that applied during cooling), which indicate that PM state is the non-equilibrium state. Among the growing list of diverse system showing glass like arrested magnetic states, the present system is the first example where, kinetic arrest is observed for a disordered (here PM) to ordered (here FM) magnetic transition.

  19. Spontaneous subarachnoid hemorrhage as a differential diagnosis of pre-hospital cardiac arrest

    Directory of Open Access Journals (Sweden)

    Sohil Pothiawala

    2012-01-01

    Full Text Available Spontaneous subarachnoid hemorrhage is the most common neurological disorder leading to pre-hospital cardiac arrest. ECG changes in SAH may mimic myocardial infarction or ischemia, and thus lead to delayed treatment of the primary problem. Early identification of SAH-induced cardiac arrest with the use of computed tomography scan of the brain obtained immediately after resuscitation will aid emergency physicians make further decisions. The overall prognosis of patients who are resuscitated is extremely poor. But, prompt neurosurgical referral and multidisciplinary intensive care management can improve the survival rate and the functional outcome. Thus, physicians should consider SAH as a differential diagnosis in patients presenting with pre-hospital cardiac arrest.

  20. Scale-up of fixed-bed chemical looping combustion

    NARCIS (Netherlands)

    Kimball, E.; Geerdink, P.; Goetheer, E.L.V.

    2011-01-01

    Fixed-bed chemical looping combustion is currently being studied experimentally with the optimization of systems up to 1 kW. One of the key advantages for using the fixed-bed configuration over fluidized-beds is the flexibility in operating parameters that allows for application of CLC not only to p

  1. Heat Transfer in a Fixed Biomass Char Bed

    DEFF Research Database (Denmark)

    Fjellerup, Jan Søren; Henriksen, Ulrik Birk; Glarborg, P.;

    2002-01-01

    A thermal conductivity model based on the Yagi and Kunii model together with a bed model was developed to describe the thermal conductivity of a straw char bed. The bed model describes the relationship between the distance between particles and the external porosity. To verify the model, thermal...

  2. Fluidization of potato starch in a stirred vibrating fluidized bed

    NARCIS (Netherlands)

    Kuipers, N.J M; Stamhuis, Eize; Beenackers, A.A C M

    1996-01-01

    A novel gas-solid reactor for cohesive C-powders such as potato starch is introduced, designed and characterized, the so-called stirred vibrating fluidized bed. The effects of a sinusoidal vibration of the gas distributor and/or stirring of the bed are investigated. The fluidization index, bed expan

  3. 21 CFR 890.5160 - Air-fluidized bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Air-fluidized bed. 890.5160 Section 890.5160 Food... DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Therapeutic Devices § 890.5160 Air-fluidized bed. (a) Identification. An air-fluidized bed is a device employing the circulation of filtered air through...

  4. 21 CFR 890.5225 - Powered patient rotation bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered patient rotation bed. 890.5225 Section 890.5225 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... rotation bed. (a) Identification. A powered patient rotation bed is a device that turns a patient who...

  5. 21 CFR 890.5180 - Manual patient rotation bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual patient rotation bed. 890.5180 Section 890.5180 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... rotation bed. (a) Identification. A manual patient rotation bed is a device that turns a patient who...

  6. 21 CFR 890.5170 - Powered flotation therapy bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered flotation therapy bed. 890.5170 Section 890.5170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Powered flotation therapy bed. (a) Identification. A powered flotation therapy bed is a device that...

  7. Core Physics of Pebble Bed High Temperature Nuclear Reactors

    NARCIS (Netherlands)

    Auwerda, G.J.

    2014-01-01

    To more accurately predict the temperature distribution inside the reactor core of pebble bed type high temperature reactors, in this thesis we investigated the stochastic properties of randomly stacked beds and the effects of the non-homogeneity of these beds on the neutronics and thermal-hydraulic

  8. Stochastic modeling in sediment dynamics: Exner equation for planar bed incipient bed load transport conditions

    Science.gov (United States)

    Ancey, Christophe

    2010-06-01

    Even under flow equilibrium conditions, river bed topography continuously evolves with time, producing trains of irregular bed forms. The idea has recently emerged that the variability in the bed form geometry results from some randomness in sediment flux. In this paper, we address this issue by using the Exner equation and a population exchange model derived in an earlier paper. In this model, particle entrainment and deposition are idealized as population exchanges between the stream and the bed, which makes it possible to use birth-death Markov process theory to track the number of moving grains. The paper focuses on nascent bed forms on initially planar beds, a situation in which the coupling between the stream and bed is weak. In a steady state, the number of moving particles follows a negative binomial distribution. Although this probability distribution does not enter the family of heavy-tailed distributions, it may give rise to large and frequent fluctuations because the standard deviation can be much larger than the mean, a feature that is not accounted for with classic probability laws (e.g., Hamamori's law) used so far for describing bed load fluctuations. In the large-system limit, the master equation of the birth-death Markov process can be transformed into a Fokker-Planck equation. This transformation is used here to show that the number of moving particles can be described as an Ornstein-Uhlenbeck process. An important consequence is that in the long term, the number of moving particles follows a Gaussian distribution. Laboratory experiments show that this approximation is correct when the mean number per unit length of stream, ?/L, is sufficiently large (typically two particles per centimeter in our experiments). The particle number fluctuations give rise to bed elevation fluctuations, whose spectrum falls off like ω-2 in the high-frequency regime (with ω the angular frequency) and variance grows linearly with time. These features are in agreement

  9. Modeling biomass gasification in circulating fluidized beds

    Science.gov (United States)

    Miao, Qi

    In this thesis, the modeling of biomass gasification in circulating fluidized beds was studied. The hydrodynamics of a circulating fluidized bed operating on biomass particles were first investigated, both experimentally and numerically. Then a comprehensive mathematical model was presented to predict the overall performance of a 1.2 MWe biomass gasification and power generation plant. A sensitivity analysis was conducted to test its response to several gasifier operating conditions. The model was validated using the experimental results obtained from the plant and two other circulating fluidized bed biomass gasifiers (CFBBGs). Finally, an ASPEN PLUS simulation model of biomass gasification was presented based on minimization of the Gibbs free energy of the reaction system at chemical equilibrium. Hydrodynamics plays a crucial role in defining the performance of gas-solid circulating fluidized beds (CFBs). A 2-dimensional mathematical model was developed considering the hydrodynamic behavior of CFB gasifiers. In the modeling, the CFB riser was divided into two regions: a dense region at the bottom and a dilute region at the top of the riser. Kunii and Levenspiel (1991)'s model was adopted to express the vertical solids distribution with some other assumptions. Radial distributions of bed voidage were taken into account in the upper zone by using Zhang et al. (1991)'s correlation. For model validation purposes, a cold model CFB was employed, in which sawdust was transported with air as the fluidizing agent. A comprehensive mathematical model was developed to predict the overall performance of a 1.2 MWe biomass gasification and power generation demonstration plant in China. Hydrodynamics as well as chemical reaction kinetics were considered. The fluidized bed riser was divided into two distinct sections: (a) a dense region at the bottom of the bed where biomass undergoes mainly heterogeneous reactions and (b) a dilute region at the top where most of homogeneous

  10. Endothelial activation/injury and associations with severity of post-cardiac arrest syndrome and mortality after out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Bro-Jeppesen, John; Johansson, Pär I; Hassager, Christian;

    2016-01-01

    BACKGROUND: Post-cardiac arrest syndrome (PCAS) is characterized by whole-body ischemia triggering systemic inflammation and damage of the endothelium. This study investigated the relationship between systemic inflammation, endothelial damage and severity of PCAS and the association between...... endothelial damage and outcome after out-of-hospital cardiac arrest (OHCA). METHODS: In this post hoc study, we analyzed 163 comatose patients included at a single center in the target temperature management (TTM) trial, randomly assigned to TTM at 33°C or 36°C for 24h. Endothelial biomarkers (syndecan-1......, thrombomodulin, sE-selectin, sVE-cadherin) and the inflammatory biomarker interleukin-6 (IL-6) were measured at admission (baseline) and 24, 48 and 72h after OHCA. Severity of PCAS was assessed by Sequential Organ Failure Assessment score. Mortality at 30-days was evaluated by Cox regression analysis. RESULTS...

  11. Temporal variation of out-of-hospital cardiac arrests in an equatorial climate

    Directory of Open Access Journals (Sweden)

    Marcus EH Ong

    2010-04-01

    Full Text Available Marcus EH Ong1, Faith SP Ng2, Susan Yap1, Kok Leong Yong1, Mary A Peberdy3, Joseph P Ornato41Department of Emergency Medicine, Singapore General Hospital, Singapore; 2Clinical Trials and Epidemiology Research Unit (now known as Singapore Clinical Research Institute, Singapore; 3Division of Cardiology, Virginia Commonwealth University – Medical College of Virginia, Richmond, VA, USA; 4Department of Emergency Medicine, Virginia Commonwealth University – Medical College of Virginia, Richmond, VA, USAObjective: We aimed to determine whether there is a seasonal variation of out-of-hospital cardiac arrests (OHCA in an equatorial climate, which does not experience seasonal environmental change.Methods: We conducted an observational prospective study looking at the occurrence of OHCA in Singapore. Included were all patients with OHCA presented to Emergency Departments across the country. We examined the monthly, daily, and hourly number of cases over a threeyear period. Data was analyzed using analysis of variance (ANOVA.Results: From October, 1st 2001 to October, 14th 2004, 2428 patients were enrolled in the study. Mean age for cardiac arrests was 60.6 years with 68.0% male. Ethnic distribution was 69.5% Chinese, 15.0% Malay, 11.0% Indian, and 4.4% Others. There was no significant seasonal variation (spring/summer/fall/winter of events (ANOVA P = 0.71, monthly variation (P = 0.88 or yearly variation (P = 0.26. We did find weekly peaks on Mondays and a circadian pattern with daily peaks from 9–10 am.Conclusions: We did not find any discernable seasonal pattern of cardiac arrests. This contrasts with findings from temperate countries and suggests a climatic influence on cardiac arrest occurrence. We also found that sudden cardiac arrests follow a circadian pattern.Keywords: cardiopulmonary resuscitation, cardiac arrest, seasonal pattern, circadian pattern

  12. Surviving Sudden Cardiac Arrest: A Pilot Qualitative Survey Study of Survivors.

    Science.gov (United States)

    Sawyer, Kelly N; Brown, Frances; Christensen, Roxanne; Damino, Colleen; Newman, Mary M; Kurz, Michael C

    2016-06-01

    Research describing survivors of sudden cardiac arrest (SCA) has centered on quantifying functional ability, perceived quality of life, and neurocognitive assessment. Many gaps remain, however, regarding survivors' psychosocial perceptions of life in the aftermath of cardiac arrest. An important influence upon those perceptions is the presence of support and its role in a survivor's life. An Internet-based pilot survey study was conducted to gather data from SCA survivors and friends and/or family members (FFMs) representing their support system. The survey was distributed to members of the Sudden Cardiac Arrest Foundation (SCAF) via the Internet by SCAF leadership. Questions included both discrete multiple-choice and open-ended formats. Inductive thematic analyses were completed by three independent researchers trained in qualitative research methodology to identify primary themes consistent among study participants until thematic saturation was achieved. No statistical inferences were made. A total of 205 surveys were returned over the 5-month study period (July to November 2013); nine were received blank, leaving 196 surveys available for review. Major themes identified for survivors (N = 157) include the significance of and desire to share experiences with others; subculture identification (unique experience from those suffering a heart attack); and the need to seek a new normal, both personally and inter-personally. Major themes identified for FFMs (N = 39) include recognition of loved one's memory loss; a lack of information at discharge, including expectations after discharge; and concern for the patient experiencing another cardiac arrest. This pilot, qualitative survey study suggests several common themes important to survivors, and FFMs, of cardiac arrest. These themes may serve as a basis for future patient-centered focus groups and the development of patient-centered guidelines for patients and support persons of those surviving cardiac arrest

  13. Cell cycle arrest by a gradient of Dpp signaling during Drosophila eye development

    Directory of Open Access Journals (Sweden)

    Bhattacharya Abhishek

    2010-03-01

    Full Text Available Abstract Background The secreted morphogen Dpp plays important roles in spatial regulation of gene expression and cell cycle progression in the developing Drosophila eye. Dpp signaling is required for timely cell cycle arrest ahead of the morphogenetic furrow as a prelude to differentiation, and is also important for eye disc growth. The dpp gene is expressed at multiple locations in the eye imaginal disc, including the morphogenetic furrow that sweeps across the eye disc as differentiation initiates. Results Studies of Brinker and Dad expression, and of Mad phosphorylation, establish that there is a gradient of Dpp signaling in the eye imaginal disc anterior to the morphogenetic furrow, predominantly in the anterior-posterior axis, and also Dpp signaling at the margins of the disc epithelium and in the dorsal peripodial membrane. Almost all signaling activity seems to spread through the plane of the epithelia, although peripodial epithelium cells can also respond to underlying disc cells. There is a graded requirement for Dpp signaling components for G1 arrest in the eye disc, with more stringent requirements further anteriorly where signaling is lower. The signaling level defines the cell cycle response, because elevated signaling through expression of an activated Thickveins receptor molecule arrested cells at more anterior locations. Very anterior regions of the eye disc were not arrested in response to activated receptor, however, and evidence is presented that expression of the Homothorax protein may contribute to this protection. By contrast to activated Thickveins, ectopic expression of processed Dpp leads to very high levels of Mad phosphorylation which appear to have non-physiological consequences. Conclusions G1 arrest occurs at a threshold level of Dpp signaling within a morphogen gradient in the anterior eye. G1 arrest is specific for one competent domain in the eye disc, allowing Dpp signaling to promote growth at earlier

  14. Surviving Sudden Cardiac Arrest: A Pilot Qualitative Survey Study of Survivors.

    Science.gov (United States)

    Sawyer, Kelly N; Brown, Frances; Christensen, Roxanne; Damino, Colleen; Newman, Mary M; Kurz, Michael C

    2016-06-01

    Research describing survivors of sudden cardiac arrest (SCA) has centered on quantifying functional ability, perceived quality of life, and neurocognitive assessment. Many gaps remain, however, regarding survivors' psychosocial perceptions of life in the aftermath of cardiac arrest. An important influence upon those perceptions is the presence of support and its role in a survivor's life. An Internet-based pilot survey study was conducted to gather data from SCA survivors and friends and/or family members (FFMs) representing their support system. The survey was distributed to members of the Sudden Cardiac Arrest Foundation (SCAF) via the Internet by SCAF leadership. Questions included both discrete multiple-choice and open-ended formats. Inductive thematic analyses were completed by three independent researchers trained in qualitative research methodology to identify primary themes consistent among study participants until thematic saturation was achieved. No statistical inferences were made. A total of 205 surveys were returned over the 5-month study period (July to November 2013); nine were received blank, leaving 196 surveys available for review. Major themes identified for survivors (N = 157) include the significance of and desire to share experiences with others; subculture identification (unique experience from those suffering a heart attack); and the need to seek a new normal, both personally and inter-personally. Major themes identified for FFMs (N = 39) include recognition of loved one's memory loss; a lack of information at discharge, including expectations after discharge; and concern for the patient experiencing another cardiac arrest. This pilot, qualitative survey study suggests several common themes important to survivors, and FFMs, of cardiac arrest. These themes may serve as a basis for future patient-centered focus groups and the development of patient-centered guidelines for patients and support persons of those surviving cardiac arrest.

  15. Survival to admission after out-of-hospital cardiac arrest in Seoul, South Korea

    Directory of Open Access Journals (Sweden)

    Kim JH

    2014-09-01

    Full Text Available Jin-Hue Kim,1 Tai-Hwan Uhm2 1Department of Emergency Medical Technology, Sun Moon University, Asan-si, Chungnam, South Korea; 2Department of Emergency Medical Services, Eulji University, Seongnam-si, Gyeonggi-do, South Korea Purpose: Out-of-hospital cardiac arrest (OHCA data derived according to the Utstein Style guidelines was used to try to determine factors influencing survival to admission (STA and epidemiological rates of OHCA. Patients and methods: This was an observational study of all age groups based on data from prehospital care reports in Seoul, South Korea. The collected data were reported according to the Utstein Style template for OHCA and analyzed in order to compare STA with non-STA. Univariate analysis was conducted using a binomial logistic regression model to identify predictors associated with trauma patients. Results: Eighty-three (4.8% OHCA survivors were admitted to the emergency department with carotid pulse. The median time from arrest to emergency medical personnel defibrillation was statistically significantly shorter in STA cases (8.0 minutes than in non-STA cases (12.0 minutes; P<0.001. Factors independently associated with better prognosis in terms of trauma patients were female sex (odds ratio [OR]: 0.67; 95% confidence interval [95% CI]: 0.50–0.91; P=0.01, arrest at home (OR: 0.36; 95% CI: 0.27–0.49; P<0.001, and witnessed arrest (OR: 2.64; 95% CI: 1.94–3.39; P<0.001. Conclusion: Early basic life support, performed by either a layperson or emergency medical personnel, had a positive effect on STA. Male sex, arrest outside of the home, and witnessed arrest are significantly associated with trauma. Keywords: Utstein Style, prehospital, defibrillation, basic life support

  16. Flow resistance of gravel bed channels

    Institute of Scientific and Technical Information of China (English)

    Wen C. WANG; David R. DAWDY

    2014-01-01

    Existing resistance formulas produce a wide range of friction-factor estimates for gravel bed streams. The purpose of this paper is to develop a reliable resistance formula in terms of the Darcy-Weisbach friction factor f. Published data were screened and used to establish the formula. The existing formulas have considered that f is a function of relative roughness D84/R only, where R is the hydraulic radius and D84 is the particle size referred to the intermediate diameter that equals or exceeds that of 84 percent of bed sediments. In this paper, f is considered as a function of Froude number in addition to the relative roughness. f for D84/R>1 displays a different trend than that for D84/R1. An f formula for D84/R<1 has been established.

  17. Boiling Heat Transfer in Circulating Fluidized Beds

    Institute of Scientific and Technical Information of China (English)

    张利斌; 李修伦

    2001-01-01

    A model is proposed to predict boiling heat transfer coefficient in a three-phase circulating fluidized bed (CFB), which is a new type of evaporation boiling means for enhancing heat transfer and preventing fouling. To verify the model, experiments are conducted in a stainless steel column with 39 mm ID and 2.0 m height, in which the heat transfer coefficient is measured for different superficial velocities, steam pressures, particle concentrations and materials of particle. As the steam pressure and particle concentrations increase, the heat transfer coefficient in the bed increases. The heat transfer coefficient increases with the liquid velocity but it exhibits a local minimum.The heat transfer coefficient is correlated with cluster renewed model and two-mechanism method. The prediction of the model is in good agreement with experimental data.

  18. Boiling Heat Transfer in Circulating Fluidized Beds

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A model is proposed to predict boiling heat transfer coefficient in a three-phase circulating fluidized bed (CFB), which is a new type of evaporation boiling means for enhancing heat transfer and preventing fouling. To verify the model, experiments are conducted in a stainless steel column with 39mm ID and 2.0m height, in which the heat transfer coefficient is measured for different superficial velocities, steam pressures, particle concentrations and materials of particle. As the steam pressure and particle concentrations increase, the heat transfer coefficient in the bed increases. The heat transfer coefficient increases with the liquid velocity but it exhibits a local minimum. The heat transfer coefficient is correlated with cluster renewed model and two-mechanism method. The prediction of the model is in good agreement with experimental data.

  19. Experimental installation with pressurized fluidized bed boiler

    Energy Technology Data Exchange (ETDEWEB)

    Dobrzanski, W.; Szwarc, W.; Jurek, K.; Prokop, A. (Politechnika Warszawska (Poland). Instytut Techniki Cieplnej)

    1990-01-01

    Describes a test installation with a 3 MW pressurized fluidized bed boiler. The installation was commissioned at the Institute of Heat Engineering at the Technical University in Warsaw. Predesign assumptions and the lay-out of the installation are given. A schematic diagram of the pressurized (0.6 MPa) fluidized bed boiler with an inner diameter of 1.4 m and a total height of 5.45 m is shown. The fuel feeding system consists of a coal and adsorbent container, two feeders and an air jet pump for pneumatic transport. A water type boiler is integrated into the pressure vessel. Flue gas cyclones are also integrated into a separate pressure vessel. The computerized control system and instrumentation are described. Temperatures, pressures, pressure differences, rotational speeds and the chemical composition of gases are monitored.

  20. Cardiac arrest in intensive care unit: Case report and future recommendations

    Directory of Open Access Journals (Sweden)

    Mohammad A

    2010-01-01

    Full Text Available Initiation of hemofiltration in a patient in septic shock can cause hemodynamic compromise potentially leading to cardiac arrest. We propose that the standard ′4Hs and 4Ts′ approach to the differential diagnosis of a cardiac arrest should be supplemented in critically ill patients with anaphylaxis and human and technical errors involving drug administration (the 5 th H and T. To illustrate the point, we report a case where norepinephrine infused through a central venous catheter (CVC was being removed by the central venovenous hemofiltration (CVVH catheter causing the hemodynamic instability. CVVH has this potential of interfering with the systemic availability of drugs infused via a closely located CVC.

  1. Withaferin-A induces mitotic catastrophe and growth arrest in prostate cancer cells

    OpenAIRE

    Roy, Ram V; Suman, Suman; Das, Trinath P; Luevano, Joe; Damodaran, Chendil

    2013-01-01

    Cell cycle deregulation is strongly associated with the pathogenesis of prostate cancer (CaP). Clinical trials of cell cycle regulators that target either the G0/G1 or G2/M phase to inhibit the growth of cancers including CaP are increasing. In this study, we determined the cell-cycle regulatory potential of the herbal molecule Withaferin-A (WA) on CaP cells. WA induced irreversible G2/M arrest in both CaP cell lines (PC3 and DU145) for 48 h. The G2/M arrest was accompanied by upregulation of...

  2. p53-Induced Growth Arrest Is Regulated by the Mitochondrial SirT3 Deacetylase

    OpenAIRE

    SiDe Li; Michaela Banck; Shiraz Mujtaba; Ming-Ming Zhou; Mary M Sugrue; Walsh, Martin J

    2010-01-01

    A hallmark of p53 function is to regulate a transcriptional program in response to extracellular and intracellular stress that directs cell cycle arrest, apoptosis, and cellular senescence. Independent of the role of p53 in the nucleus, some of the anti-proliferative functions of p53 reside within the mitochondria [1]. p53 can arrest cell growth in response to mitochondrial p53 in an EJ bladder carcinoma cell environment that is naïve of p53 function until induced to express p53 [2]. TP53 can...

  3. Modeling and Simulation of Arresting Gear System with Multibody Dynamic Approach

    OpenAIRE

    Wenhou Shen; Zhihua Zhao; Gexue Ren; Jiapeng Liu

    2013-01-01

    The arresting dynamics of the aircraft on the aircraft carrier involves both a transient wave propagation process in rope and a smooth decelerating of aircraft. This brings great challenge on simulating the whole process since the former one needs small time-step to guarantee the stability, while the later needs large time-step to reduce calculation time. To solve this problem, this paper proposes a full-scale multibody dynamics model of arresting gear system making use of variable time-step ...

  4. Genetic, clinical and pharmacological determinants of out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Blom, M T; van Hoeijen, D A; Bardai, A;

    2014-01-01

    victims since June 2005, we prospectively collect medical history (through hospital and general practitioner), and current and previous medication use (through community pharmacy). In addition, we include DNA samples from OHCA victims with documented ventricular tachycardia/fibrillation during...... the resuscitation attempt since July 2007. Various study designs are employed to analyse the data of the ARREST registry, including case-control, cohort, case only and case-cross over designs. ETHICS AND DISSEMINATION: We describe the rationale, outline and potential results of the ARREST registry. The design...

  5. Survival after out-of-hospital cardiac arrest in relation to sex

    DEFF Research Database (Denmark)

    Wissenberg, Mads; Hansen, Carolina Malta; Folke, Fredrik;

    2014-01-01

    AIM: Crude survival has increased following an out-of-hospital cardiac arrest (OHCA). We aimed to study sex-related differences in patient characteristics and survival during a 10-year study period. METHODS: Patients≥12 years old with OHCA of a presumed cardiac cause, and in whom resuscitation...... was attempted, were identified through the Danish Cardiac Arrest Registry 2001-2010. A total of 19,372 patients were included. RESULTS: One-third were female, with a median age of 75 years (IQR 65-83). Compared to females, males were five years younger; and less likely to have severe comorbidities, e...

  6. Association between prehospital physician involvement and survival after out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Hamilton, Annika; Steinmetz, Jacob; Wissenberg, Mads;

    2016-01-01

    involvement and 30-day survival. METHODS: Observational study including persons registered with first-time OHCA of any cause in the Danish Cardiac Arrest Registry during 2005-2012. We used logistic regression analysis to assess the association between 30-day survival and involvement of a physician at any time......AIM: Sudden out-of-hospital cardiac arrest (OHCA) is an important public health problem. While several interventions are known to improve survival, the impact of physician-delivered advanced cardiac life support for OHCA is unclear. We aimed to assess the association between prehospital physician...

  7. Out-of-Hospital Cardiac Arrests and Outdoor Air Pollution Exposure in Copenhagen, Denmark

    DEFF Research Database (Denmark)

    Wichmann, Janine; Folke, Fredrik; Torp-Pedersen, Christian;

    2013-01-01

    Cardiovascular disease is the number one cause of death globally and air pollution can be a contributing cause. Acute myocardial infarction and cardiac arrest are frequent manifestations of coronary heart disease. The objectives of the study were to investigate the association between 4 657 out......-of-hospital cardiac arrests (OHCA) and hourly and daily outdoor levels of PM(10), PM(2.5), coarse fraction of PM (PM(10-2.5)), ultrafine particle proxies, NO(x), NO(2), O(3) and CO in Copenhagen, Denmark, for the period 2000-2010. Susceptible groups by age and sex was also investigated. A case-crossover design...

  8. Prehospital therapeutic hypothermia after cardiac arrest--from current concepts to a future standard.

    Science.gov (United States)

    Kämäräinen, Antti; Hoppu, Sanna; Silfvast, Tom; Virkkunen, Ilkka

    2009-01-01

    Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects. PMID:19821967

  9. Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

    Directory of Open Access Journals (Sweden)

    Hoppu Sanna

    2009-10-01

    Full Text Available Abstract Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects.

  10. Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

    Science.gov (United States)

    Kämäräinen, Antti; Hoppu, Sanna; Silfvast, Tom; Virkkunen, Ilkka

    2009-01-01

    Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects. PMID:19821967

  11. Technology-facilitated Organized Abuse: An Examination of Law Enforcement Arrest Cases

    Directory of Open Access Journals (Sweden)

    Janis Wolak

    2015-07-01

    Full Text Available This paper looks at cases of organized abuse (that is, two or more offenders working in concert and having two or more victims, not solely familial reported by law enforcement respondents during the three waves of the National Juvenile Online Victimization (NJOV Study (n=29. The NJOV Study collected data from a national US sample of law enforcement agencies about technology-facilitated crimes ending in arrest at three time points: mid-2000 to mid-2001, 2005 and 2009. The paper reports on the prevalence of technology-facilitated organized abuse ending in arrest, contexts of cases and characteristics of offenders and victims. 

  12. The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.

    Directory of Open Access Journals (Sweden)

    Sarai Pacheco

    2015-03-01

    Full Text Available Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the double-strand breaks (DSBs that initiate meiotic recombination, and another activated by persistent recombination intermediates. Mechanisms underlying the recombination-dependent arrest response are not well understood, so we sought to identify factors involved by examining mutants deficient for TRIP13, a conserved AAA+ ATPase required for the completion of meiotic DSB repair. We find that spermatocytes with a hypomorphic Trip13 mutation (Trip13mod/mod arrest with features characteristic of early pachynema in wild type, namely, fully synapsed chromosomes without incorporation of the histone variant H1t into chromatin. These cells then undergo apoptosis, possibly in response to the arrest or in response to a defect in sex body formation. However, TRIP13-deficient cells that additionally lack the DSB-responsive kinase ATM progress further, reaching an H1t-positive stage (i.e., similar to mid/late pachynema in wild type despite the presence of unrepaired DSBs. TRIP13-deficient spermatocytes also progress to an H1t-positive stage if ATM activity is attenuated by hypomorphic mutations in Mre11 or Nbs1 or by elimination of the ATM-effector kinase CHK2. These mutant backgrounds nonetheless experience an apoptotic block to further spermatogenic progression, most likely caused by failure to form a sex body. DSB numbers are elevated in Mre11 and Nbs1 hypomorphs but not Chk2 mutants, thus delineating genetic requirements for the ATM-dependent negative feedback loop that regulates DSB numbers. The findings demonstrate for the first time that ATM-dependent signaling enforces the normal pachytene response to persistent recombination intermediates. Our work supports the conclusion that recombination defects trigger

  13. Crack arrest model for a piezoelectric strip subjected to Model loadings

    OpenAIRE

    R.R. Bhargava; A. Setia

    2007-01-01

    Purpose: The present paper aims at proposing a crack arrest model for an infinitely long narrow, poled ceramic strip weakened by a finite hairline straight crack when the edges of the strip are subjected to combined mechanical and electrical loads.Design/methodology/approach: (Model) As a consequence of loads the rims of crack open forming a yield zone ahead of each tip of the crack. To arrest the crack from further opening the rims of the yield zones are subjected to normal cohesive quadra...

  14. Cardiac arrest after sugammadex administration in a patient with variant angina: a case report

    Science.gov (United States)

    Kim, Yong Han; Kang, Eunsu; Lee, Byeong-Cheol; Lee, Sujung

    2016-01-01

    A 76-year-old man with no notable medical history was scheduled for a robot-assisted radical prostatectomy. After the operation, he was given sugammadex. Two minutes later, ventricular premature contraction bigeminy began, followed by cardiac arrest. Cardiac arrest occurred three times and cardiopulmonary resuscitation was done. The patient recovered after the third cardiopulmonary resuscitation and was transferred to the intensive care unit. Coronary angiography was done on postoperative day 1. The patient was diagnosed with variant angina and discharged uneventfully on postoperative day 8.

  15. Recovery of brain function after cardiac arrest, case report and review.

    Science.gov (United States)

    Nekoui, A; Tresierra, del Carmen Escalante; Abdolmohammadi, S; Charbonneau, S; Blaise, G

    2016-01-01

    Cerebral hypoxia during cardiac arrest is the leading cause of mortality and morbidity in survival victims. To reduce cerebral damage, studies focus on finding effective treatments during the resuscitation period. Our report focuses on a 36-year-old police officer who had had two cardiac arrests (one at home and one at the hospital). After acute treatment, his cardiac and brain functions recovered impressively. Neuropsychological results were normal except for mild anomia. He also reported some retrograde memory loss. Surprisingly, he also reported an improvement in a very specific capacity, his episodic memory. We here review the possible causes and mechanisms that may have affected his memory abilities.

  16. Women's perspectives on the context of violence and role of police in their intimate partner violence arrest experiences.

    Science.gov (United States)

    Li, Simiao; Levick, Ani; Eichman, Adelaide; Chang, Judy C

    2015-02-01

    Intimate partner violence (IPV) accounts for up to 50% of all calls to police. In an effort to standardize arrest criteria, mandatory arrest laws were established. It is unclear whether subsequent increased rates of female arrest are due to greater recognition of female IPV perpetrators or of women acting in self-defense. This study aims to understand the context and consequences of IPV-related arrest from perspectives of women arrested in a single metropolitan area. Semi-structured qualitative interviews were conducted with women arrested and court-ordered to attend IPV education groups at a women's shelter in the Northeast United States. Interviews addressed circumstances surrounding arrest, experience with past violence, and reasoning regarding use of partner violence. Two researchers independently coded transcripts and met to iteratively refine the code and review transcripts for themes. Eighteen women were interviewed. Major themes that emerged were as follows: (a) Women's use of violence occurred within the context of their own victimization; (b) the arrest included a complex interplay between subject, partner, and police; (c) women perceived police arrest decisions to be based on a limited understanding of context; and (d) women experienced both positive and negative consequences of arrest. Many relationships did not fall under the traditional victim/perpetrator construct. Rather, women's use of violence evolved, influenced by prior experiences with violence. More appropriate methods must be developed for making arrest decisions, guiding justice system responses, and developing interventions for couples experiencing IPV. Recognition that women's use of partner violence often represented either a retaliatory or self-defensive gesture within the context of prior victimization suggests that victims' interventions should not only focus on empowerment but also provide skills and strategies to avoid temptation to adopt aggression as a primary method of self-protection.

  17. Cluster Dynamics in a Circulating Fluidized Bed

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, C.P.; Breault, R.W.

    2006-11-01

    A common hydrodynamic feature in industrial scale circulating fluidized beds is the presence of clusters. The continuous formation and destruction of clusters strongly influences particle hold-up, pressure drop, heat transfer at the wall, and mixing. In this paper fiber optic data is analyzed using discrete wavelet analysis to characterize the dynamic behavior of clusters. Five radial positions at three different axial locations under five different operating were analyzed using discrete wavelets. Results are summarized with respect to cluster size and frequency.

  18. A multistage model of hospital bed requirements.

    OpenAIRE

    Pendergast, J F; Vogel, W B

    1988-01-01

    This article presents a model for projecting future hospital bed requirements, based on clinical judgment and basic probability theory. Clinical judgment is used to define various categories of care, including a category for patients who are inappropriately hospitalized, for a large teaching hospital with a heavy indigent and psychiatric workload. Survey results and discharge abstract data are then used to calculate expected discharges and patient days for each clinical category. These expect...

  19. A Primer on Wound Bed Preparation

    OpenAIRE

    Gokoo, Chuck

    2009-01-01

    Successful wound closure and healing are a major concern for today's clinician. Determining if the wound will progress or not relies on a comprehensive assessment, recognition of wound characteristics that will promote or impede the healing process and preparing the wound bed such that pathological features are removed allowing the healing cascade to occur. When complications are no longer a roadblock the wound will achieve a stable microenvironment and progress through the normal repairative...

  20. Susceptibility of Bed Bugs to Insecticides

    Directory of Open Access Journals (Sweden)

    P. Damodar

    1964-04-01

    Full Text Available The susceptibility of a normal laboratory strain of the bed bug, cimex hemipterus fabricius to certain synthetic insecticides, viz. dieldrin, diazinon and malathion was investigated in relation to DDT and lindance. The data were subjected to probit analysis. It was found that diazinon was the most effective insecticide, as residual films on filter papers, and was followed by malathion, lindane and DDT/dieldrin. It was also found that c. hemipterus was fairly susceptible to all the insecticides investigated.

  1. Circulating fluidized bed boilers design and operations

    CERN Document Server

    Basu, Prabir

    1991-01-01

    This book provides practicing engineers and students with insight into the design and operation of circulating fluidized bed (CFB) boilers. Through a combination of theoretical concepts and practical experience, this book gives the reader a basic understanding of the many aspects of this subject.Important environmental considerations, including solid waste disposal and predicted emissions, are addressed individually in separate chapters. This book places an emphasis on combustion, hydrodynamics, heat transfer, and material issues, and illustrates these concepts with numerous examples of pres

  2. Reference repository design concept for bedded salt

    International Nuclear Information System (INIS)

    A reference design concept is presented for the subsurface portions of a nuclear waste repository in bedded salt. General geologic, geotechnical, hydrologic and geochemical data as well as descriptions of the physical systems are provided for use on generic analyses of the pre- and post-sealing performance of repositories in this geologic medium. The geology of bedded salt deposits and the regional and repository horizon stratigraphy are discussed. Structural features of salt beds including discontinuities and dissolution features are presented and their effect on repository performance is discussed. Seismic hazards and the potential effects of earthquakes on underground repositories are presented. The effect on structural stability and worker safety during construction from hydrocarbon and inorganic gases is described. Geohydrologic considerations including regional hydrology, repository scale hydrology and several hydrological failure modes are presented in detail as well as the hydrological considerations that effect repository design. Operational phase performance is discussed with respect to operations, ventilation system, shaft conveyances, waste handling and retrieval systems and receival rates of nuclear waste. Performance analysis of the post sealing period of a nuclear repository is discussed, and parameters to be used in such an analysis are presented along with regulatory constraints. Some judgements are made regarding hydrologic failure scenarios. Finally, the design and licensing process, consistent with the current licensing procedure is described in a format that can be easily understood

  3. Single-stage fluidized-bed gasification

    Science.gov (United States)

    Lau, F. S.; Rue, D. M.; Weil, S. A.; Punwani, D. V.

    1982-04-01

    The single-stage fluidized-bed gasification process, in addition to being a simple system, maximizes gas production and allows the economic exploitation of small peat deposits. The objective of this gasification project is to conduct experiments in order to obtain data for designing a single-stage fluidized-bed gasifier, and to evaluate the economics of converting peat to synthesis gas and to SNG by this process. An existing high-temperature and high-pressure process development unit (PDU) was modified to permit the direct feeding of peat to the fluidized bed. Peat flows by gravity from the feed hopper through a 6-inch line to the screw-feeder conveyor. From there, it is fed to the bottom tee section of the reactor and transported into the gasification zone. Oxygen and steam are fed through a distributing ring into the reactor. Gasification reactions occur in the annulus formed by the reactor tube and a central standpipe. Peat ash is discharged from the reactor by overflowing into the standpipe and is collected in a solids receiver.

  4. Status of the fluidized bed unit

    Energy Technology Data Exchange (ETDEWEB)

    Williams, P.M.; Wade, J.F.

    1994-06-01

    Rocky Flats has a serious mixed waste problem. No technology or company has a license and available facilities to remedy this dilemma. One solution under study is to use a catalytic fluidized bed unit to destroy the combustible portion of the mixed waste. The fluidized bed thermal treatment program at Rocky Flats is building on knowledge gained over twenty years of successful development activity. The FBU has numerous technical advantages over other thermal technologies to treat Rocky Flats` mixed waste, the largest being the lower temperature (700{degrees}C versus 1000{degrees}C) which reduces acid corrosion and mechanical failures and obviates the need for ceramic lining. Successful demonstrations have taken place on bench, pilot, and full-scale tests using radioactive mixed wastes. The program is approaching implementation and licensing of a production-scale fluidized bed system for the safe treatment of mixed waste. The measure for success on this project is the ability to work closely with the community to jointly solve problems and respond to concerns of mixed waste treatment at Rocky Flats.

  5. Trykfald over en bed af fliskoks

    DEFF Research Database (Denmark)

    Hindsgaul, Claus; Henriksen, Ulrik Birk

    En (atmosfærisk) luftstrøm ledtes gennem en fast bed af delvist forgasset fliskoks med en binær partikelstørrelsesfordeling (8 og 16 mm). Under variation af størrelsesfordeling og strømningshastighed registreredes det resulterende trykfald gennem bedden. Eksisterende estimationsformler for trykfa......En (atmosfærisk) luftstrøm ledtes gennem en fast bed af delvist forgasset fliskoks med en binær partikelstørrelsesfordeling (8 og 16 mm). Under variation af størrelsesfordeling og strømningshastighed registreredes det resulterende trykfald gennem bedden. Eksisterende estimationsformler...... for trykfaldet blev valideret for de givne kokspartikler. Note: Dette er en bearbejdning af rapporten “Trykfald over en Bed af Fliskoks” ved Donovan og Hindsgaul 1997 [1]. I nogle tilfælde er brugen af symboler ændret i forhold til rapporten for at opnå bedre konsistens ligesom fundne fejl er rettet. Både den...

  6. Direct contact condensation in packed beds

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yi; Klausner, James F.; Mei, Renwei; Knight, Jessica [Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611 (United States)

    2006-12-15

    A diffusion driven desalination process was recently described where a very effective direct contact condenser with a packed bed is used to condense water vapor out of an air/vapor mixture. A laboratory scale direct contact condenser has been fabricated as a twin tower structure with two stages, co-current and countercurrent. Experiments have been operated in each stage with respective saturated air inlet temperatures of 36, 40 and 43{sup o}C. The temperature and humidity data have been collected at the inlet and exit of the packed bed for different water to air mass flow ratios that vary between 0 and 2.5. A one-dimensional model based on conservation principles has been developed, which predicts the variation of temperature, humidity, and condensation rate through the condenser stages. Agreement between the model and experiments is very good. It is observed that the countercurrent flow stage condensation effectiveness is significantly higher than that for the co-current stage. The condensation heat and mass transfer rates were found to decrease when water blockages occur within the packed bed. Using high-speed digital cinematography, it was observed that this problem can occur at any operating condition, and is dependent on the packing surface wetting characteristics. This observation is used to explain the requirement for two different empirical constants, depending on packing diameter, suggested by Onda for the air side mass transfer coefficient correlation. (author)

  7. Reference repository design concept for bedded salt

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, D.W.; Martin, R.W.

    1980-10-08

    A reference design concept is presented for the subsurface portions of a nuclear waste repository in bedded salt. General geologic, geotechnical, hydrologic and geochemical data as well as descriptions of the physical systems are provided for use on generic analyses of the pre- and post-sealing performance of repositories in this geologic medium. The geology of bedded salt deposits and the regional and repository horizon stratigraphy are discussed. Structural features of salt beds including discontinuities and dissolution features are presented and their effect on repository performance is discussed. Seismic hazards and the potential effects of earthquakes on underground repositories are presented. The effect on structural stability and worker safety during construction from hydrocarbon and inorganic gases is described. Geohydrologic considerations including regional hydrology, repository scale hydrology and several hydrological failure modes are presented in detail as well as the hydrological considerations that effect repository design. Operational phase performance is discussed with respect to operations, ventilation system, shaft conveyances, waste handling and retrieval systems and receival rates of nuclear waste. Performance analysis of the post sealing period of a nuclear repository is discussed, and parameters to be used in such an analysis are presented along with regulatory constraints. Some judgements are made regarding hydrologic failure scenarios. Finally, the design and licensing process, consistent with the current licensing procedure is described in a format that can be easily understood.

  8. Fluidized-bed reactors processes and operating conditions

    CERN Document Server

    Yates, John G

    2016-01-01

    The fluidized-bed reactor is the centerpiece of industrial fluidization processes. This book focuses on the design and operation of fluidized beds in many different industrial processes, emphasizing the rationale for choosing fluidized beds for each particular process. The book starts with a brief history of fluidization from its inception in the 1940’s. The authors present both the fluid dynamics of gas-solid fluidized beds and the extensive experimental studies of operating systems and they set them in the context of operating processes that use fluid-bed reactors. Chemical engineering students and postdocs as well as practicing engineers will find great interest in this book.

  9. Some hydrodynamic aspects of 3-phase inverse fluidized bed

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Hydrodynamics of 3-phase inverse fluidized bed is studied experimentally using low density particles for different liquid and gas velocities.The hydrodynamic characteristics studied include pressure drop, minimum liquid and gas fluidization velocities and phase holdups. The minimum liquid fluidization velocity determined using the bed pressure gradient, decreases with increase in gas velocity. The axial profiles of phase holdups shows that the liquid holdup increases along the bed height, whereas the solid holdup decreases down the bed. However, the gas holdup is almost uniform in the bed.

  10. Kinetic behavior of solid particles in fluidized beds

    Energy Technology Data Exchange (ETDEWEB)

    Kono, H.O.

    1990-06-01

    The overall objectives of this project are to develop experimental techniques for measuring the forces of fluidized particles, and to predict the solid-gas performance in fluidized beds by using data analysis system, and by elucidating the intrinsic mechanism of erosion and attrition phenomena in fluidized beds. The reduction of erosion and attrition rates is one of the critical engineering problems for the design and operation of fluidized bed combustors. Specifically, the objectives are to: (1) develop the experimental techniques to measure the forces of solid particles prevailing in fluidized beds: (2) measure and characterize the forces of solid particles in various types of fluidized beds with various configurations (conventional and spouted fluidized beds) and with different scales (10, 20, and 30cm) under various fluidization conditions (particle size, bed aspect ratio and gas velocity); (3) find and verify the mechanism of erosion rates of in-bed tubes and attrition rates of fluidized particles by forces of solid particles in fluidized beds. We developed three different kinds of measurement methods, i.e., fracture sensitive sensor, piezoelectric sensor and gas pressure fluctuation method. By using these methods the exact forces of solid particles, including the transient corporate in fluidized beds, were systematically measured. Simultaneously, the erosion rates of in-bed tubes and attrition rates of fluidized particles were measured. 69 figs., 9 tabs.

  11. Bed-To-Wall Heat Transfer in a Supercritical Circulating Fluidised Bed Boiler

    Directory of Open Access Journals (Sweden)

    Błaszczuk Artur

    2014-06-01

    Full Text Available The purpose of this work is to find a correlation for heat transfer to walls in a 1296 t/h supercritical circulating fluidised bed (CFB boiler. The effect of bed-to-wall heat transfer coefficient in a long active heat transfer surface was discussed, excluding the radiation component. Experiments for four different unit loads (i.e. 100% MCR, 80% MCR, 60% MCR and 40% MCR were conducted at a constant excess air ratio and high level of bed pressure (ca. 6 kPa in each test run. The empirical correlation of the heat transfer coefficient in a large-scale CFB boiler was mainly determined by two key operating parameters, suspension density and bed temperature. Furthermore, data processing was used in order to develop empirical correlation ranges between 3.05 to 5.35 m·s-1 for gas superficial velocity, 0.25 to 0.51 for the ratio of the secondary to the primary air, 1028 to 1137K for bed temperature inside the furnace chamber of a commercial CFB boiler, and 1.20 to 553 kg·m-3 for suspension density. The suspension density was specified on the base of pressure measurements inside the boiler’s combustion chamber using pressure sensors. Pressure measurements were collected at the measuring ports situated on the front wall of the combustion chamber. The obtained correlation of the heat transfer coefficient is in agreement with the data obtained from typical industrial CFB boilers.

  12. A review on packed bed solar energy storage systems

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Harmeet; Saini, R.P. [Alternate Hydro Energy Centre, Indian Institute of Technology Roorkee, Roorkee 247667 (India); Saini, J.S. [Mechanical and Industrial Engineering Department, Indian Institute of Technology Roorkee, Roorkee 247667 (India)

    2010-04-15

    Because of intermittent nature of solar energy, storage is required for uninterrupted supply in order to match the needs. Packed beds are generally used for storage of thermal energy from solar air heaters. A packed bed is a volume of porus media obtained by packing particles of selected material into a container. A number of studies carried out on packed beds for their performance analysis were reported in the literature. These studies included the design of packed beds, materials used for storage, heat transfer enhancement, flow phenomenon and pressure drop through packed beds. This paper presents an extensive review on the research carried out on packed beds. Based on the literature review, it is concluded that most of the studies carried out are on rocks and pebbles as packing material. A very few studies were conducted on large sized packing materials. Further no study has been reported so far on medium sized storage elements in packed beds. (author)

  13. Bed mixing dryer for high moisture content fuels

    Energy Technology Data Exchange (ETDEWEB)

    Hulkkonen, S.; Heinonen, O. [Imatran Voima Oy, Vantaa (Finland)

    1997-07-01

    A bed mixing dryer is a new fuel drying technology used with fluidized bed combustion. Hot bed material is extracted from the fluidized bed and used directly as a heat source to dry the fuel. Imatran Voima Oy (IVO) in Finland has been developing the bed mixing drying technology since the early 1990s. The first pilot plant was built in 1994 at IVO's Kuusamo peat- and wood-fired power plant. The capacity of the plant is 6 MW of electricity and 20 MW of district heat. In Kuusamo the dryer is connected to a bubbling fluidized bed. Since its commissioning in 1994, the pilot dryer has been used successfully for about 3000 hours during the winter heating seasons. The next application of the bed mixing dryer will be a demonstration project in Orebro in Sweden. The fuel to be dried there is sawdust. (author)

  14. Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

    NARCIS (Netherlands)

    Agami, R.; Bernards, R.A.

    2000-01-01

    DNA damage causes stabilization of p53, leading to G1 arrest through induction of p21cip1. As this process requires transcription, several hours are needed to exert this response. We show that DNA damage causes an immediate and p53-independent G1 arrest, caused by rapid proteolysis of cyclin D1. Deg

  15. POST-OPERATIVE VENTRICULAR TACHYCARDIA LEADING TO CARDIAC ARREST IN AN ASAG- I PATIENT OF CHOLECYSTECTOMY: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Pradip

    2014-03-01

    Full Text Available We here present our experience with ventricular tachycardia (VT leading to cardiac arrest in a patient with American Society of Anesthesiologists grade-I (ASA-I 11 hours after cholecystectomy. Excessive fluid overload and hypoxemia due to lung congestion may lead to cardiac arrest in this case. Immediate diagnosis and appropriate intervention saved the life of the patient.

  16. Complex Systems Analysis of Arrested Neural Cell Differentiation during Development and Analogous Cell Cycling Models in Carcinogenesis

    OpenAIRE

    Baianu, Professor I.C.; Prisecaru, M.S. V

    2004-01-01

    A new approach to the modular, complex systems analysis of nonlinear dynamics of arrested neural cell Differentiation--induced cell proliferation during organismic development and the analogous cell cycling network transformations involved in carcinogenesis is proposed. Neural tissue arrested differentiation that induces cell proliferation during perturbed development and Carcinogenesis are complex processes that involve dynamically inter-connected biomolecules in the intercellular, membrane...

  17. Importance of the First Link Description and Recognition of an Out-of-Hospital Cardiac Arrest in an Emergency Call

    NARCIS (Netherlands)

    J. Berdowski; F. Beekhuis; A.H. Zwinderman; J.G.P. Tijssen; R.W. Koster

    2009-01-01

    Background-The content of emergency calls for suspected cardiac arrest is rarely analyzed. This study investigated the recognition of a cardiac arrest by dispatchers and its influence on survival rates. Methods and Results-During 8 months, voice recordings of 14 800 consecutive emergency calls were

  18. Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1

    NARCIS (Netherlands)

    Collado, M.; Medema, R.H.; Garcia-Cao, I.; Dubuisson, M.L.N.; Barradas, M.; Glassford, J.; Rivas, C.; Burgering, B.M.T.; Serrano, M.; Lam, E.W.-F.

    2000-01-01

    A senescence-like growth arrest is induced in mouse primary embryo fibroblasts by inhibitors of phosphoinositide 3-kinase (PI3K). We observed that senescence-like growth arrest is correlated with an increase in p27Kip1 but that down-regulation of other cyclin-dependent kinase (CDK) inhibitors, inclu

  19. Efficacy analysis of intravenous thrombolysis after cardiopulmonary resuscitation for patients with acute myocardial infarction and cardiac arrest

    Institute of Scientific and Technical Information of China (English)

    张晓丽

    2014-01-01

    Objective To explore the clinical value of intravenous thrombolysis in the treatment of patients with acute myocardial infarction(AMI)and cardiac arrest after cardiopulmonary resuscitation.Methods 120 patients with AMI and cardiac arrest admitted in our hospital from Mar2009 to Mar 2013 were divided into thrombolytic group(n=50)and control group(n=70)according to the

  20. Automated external defibrillators inaccessible to more than half of nearby cardiac arrests in public locations during evening, nighttime, and weekends

    DEFF Research Database (Denmark)

    Hansen, Carolina Malta; Wissenberg, Mads; Weeke, Peter;

    2013-01-01

    BACKGROUND: Despite wide dissemination, use of automated external defibrillators (AEDs) in community settings is limited. We assessed how AED accessibility affected coverage of cardiac arrests in public locations. METHODS AND RESULTS: We identified cardiac arrests in public locations (1994-2011) ...

  1. Survival of male patients with spinal cord injury after cardiac arrest in Department of Veterans Affairs hospital: Pilot study

    Directory of Open Access Journals (Sweden)

    Deborah Caruso, MD

    2014-11-01

    Full Text Available Survivability characteristics after cardiopulmonary resuscitation in the population with spinal cord injury (SCI are unclear but may be useful for advanced care planning discussions with patients. Retrospective evaluation from records of all SCI patients over 10 yr at a Department of Veterans Affairs medical center who experienced in-hospital cardiac arrest was performed. Demographic data and other common measurements were recorded. Thirty-six male subjects were identified, and only two patients survived to discharge (5.5% survival rate, both of whom were admitted for nonacute issues and were asymptomatic shortly before the cardiac arrest. The mean age at the time of cardiopulmonary arrest was 62.4 yr, with a mean time from cardiac arrest to death of 3.02 d. No significant demographic parameters were identified. Overall, SCI likely portends worse outcome for acutely ill patients in the situation of a cardiac arrest. Conclusions are limited by sample size.

  2. Microvascular hemodynamics in human hypothermic circulatory arrest and selective antegrade cerebral perfusion

    NARCIS (Netherlands)

    P.W.G. Elbers; A. Ozdemir; R.H. Heijmen; J. Heeren; M. van Iterson; E.P.A. van Dongen; C. Ince

    2010-01-01

    Objective: The behavior of the human microcirculation in the setting of cardiac arrest is largely unknown. Animal experiments have consistently revealed that global hemodynamics do not necessarily reflect microvascular perfusion. In addition, the time it takes for capillary blood flow to stop after

  3. Time-differentiated target temperature management after out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Kirkegaard, Hans; Rasmussen, Bodil S; de Haas, Inge;

    2016-01-01

    24 or 48 hours. Inclusion criteria are: age older than 17 and below 80 years; presumed cardiac origin of arrest; and Glasgow Coma Score (GCS) <8, on admission. The primary outcome is neurological outcome at 6 months using the Cerebral Performance Category score (CPC) by an assessor blinded to...

  4. Quantifying police officers' arrest and self-defence skills : Does performance decrease under pressure?

    NARCIS (Netherlands)

    Nieuwenhuys, Arne; Caljouw, Simone R.; Leijsen, Maaike R.; Schmeits, Bart A. J.; Oudejans, Raoul R. D.

    2009-01-01

    This study investigated police officers' performance on five selected arrest and self-defence skills that are regularly used in the line of duty. In Experiment 1 a 5-point scale to measure skill performance was developed and tested with 14 police instructors. Results showed that the new scale has sa

  5. Respiratory arrest due to nitrofurantoin treatment in the absence of pulmonary pathology

    OpenAIRE

    Çoban, Hikmet

    2015-01-01

    In the case we present, an elderly female patient developed respiratory arrest in the absence of pulmonary pathology after using nitrofurantoin (NF). To our current knowledge, this case is the first in the literature. The patient was monitored on mechanical ventilation, and her condition improved only after discontinuing NF treatment.

  6. Requirement of ultra-high voltage GIS arrester to voltage gradient of metal-oxide varistor

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The surge arrester with excellent protection characteristics would decrease the overvoltage level ap- plied on the power apparatus to reduce their insulation levels and manufacturing bottleneck. The arrester for the 1000-kV ultra-high voltage ac power transmission system is designed as tank-type structure. The field-circuit combination numerical method combining the three-dimensional finite element method with circuit is proposed to analyze the potential distribution of GIS arrester. By comparing several design schemes, the most effective method to improve the potential distribution along the varistor column is to increase the voltage gradient of the ZnO varistor. Synthesizing several influential factors, the suitable voltage gradient of ZnO varistor should be controlled to 435 V/mm, and the resulted nonuniform degree of the potential distribution along the varistor column inside the GIS arrester would be controlled smaller than 10%. The result in this paper provides the fundamental technical index for the study of the high voltage gradient ZnO varistors.

  7. "The Day They Came to Arrest the Book": Censorship and a Civil Debate.

    Science.gov (United States)

    Berger, Peter N.

    1998-01-01

    Describes the book "The Day They Came to Arrest the Book," which tells the story of a controversy involving a teacher, students, parents, administrators, and school board regarding the attempt to ban in one school district Mark Twain's book "The Adventures of Huckleberry Finn." Lists 10 activities intended to stimulate student response. (SR)

  8. 14 CFR 1203b.105 - Use of non-deadly physical force when making an arrest.

    Science.gov (United States)

    2010-01-01

    ... believes to be the use or threat of imminent use of non-deadly physical force by the offender. Verbal abuse... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Use of non-deadly physical force when... Use of non-deadly physical force when making an arrest. When a security force officer has the right...

  9. 10 CFR 1047.6 - Use of physical force when making an arrest.

    Science.gov (United States)

    2010-01-01

    ... physical force by the offender. It should be noted that verbal abuse alone by the offender cannot be the... 10 Energy 4 2010-01-01 2010-01-01 false Use of physical force when making an arrest. 1047.6... BY PROTECTIVE FORCE OFFICERS General Provisions § 1047.6 Use of physical force when making an...

  10. Evaluation of an Innovative Post-Arrest Diversion Program: 12-Month Recidivism Analysis

    Science.gov (United States)

    Dembo, Richard; Walters, Wansley; Wareham, Jennifer; Burgos, Catherimarty; Schmeidler, James; Hoge, Robert; Underwood, Lee

    2008-01-01

    We report the results of an evaluation study of a diversion program, operated by the Miami-Dade County Juvenile Assessment Center in Florida. The Post-Arrest Diversion (PAD) program represents an innovative approach to treatment and intervention within the juvenile justice system that utilizes standardized psychosocial risks and needs assessment…

  11. Cardiac arrest during treatment of Pneumocystis carinii pneumonia with intravenous pentamidine isethionate

    DEFF Research Database (Denmark)

    Balslev, U; Berild, D; Nielsen, T L

    1992-01-01

    A 27-year-old man, HIV-positive for 4 years, developed ventricular fibrillation and cardiac arrest during treatment of Pneumocystis carinii pneumonia with intravenous pentamidine isethionate. The dosage was 4 mg/kg/day for 18 days. Nephrotoxicity occurred and raised serum potassium. The plasma...

  12. Central origin of respiratory arrest in beta-blocker intoxication in rats

    NARCIS (Netherlands)

    Langemeijer, J.J.M.; Wildt, D.J. de; Groot, G. de; Sangster, B.

    1987-01-01

    Propranolol HCl (7.5 mg·kg−1), timolol maleate (7.0 mg·kg−1), and sotalol HCl (10 mg·kg−1) were administered intracerebroventricularly (icv) to spontaneously breathing (SB) rats. The respiratory rate declined until the rats all died from respiratory arrest. Artificial ventilation resulted in surviva

  13. Role of micronised progesterone in maintenance therapy following arrested preterm labor: a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Gitika Shankar Mishra

    2014-08-01

    Conclusions: We conclude that, maintenance tocolytic therapy with micronised progesterone (400 mg up-to 37 weeks of gestation in patients with arrested preterm labor significantly prolongs the latency period and results in better perinatal outcome. [Int J Reprod Contracept Obstet Gynecol 2014; 3(4.000: 1050-1055

  14. Sinus bradycardia during hypothermia in comatose survivors of out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Hassager, Christian; Bro-Jeppesen, John;

    2015-01-01

    BACKGROUND: Bradycardia is a common finding in patients undergoing therapeutic hypothermia (TH) following out-of-hospital cardiac arrest (OHCA), presumably as a normal physiological response to low body temperature. We hypothesized that a normal physiological response with sinus bradycardia (SB) ...

  15. The role of peer arrests on the development of youths' attitudes towards the justice system.

    Science.gov (United States)

    Fine, Adam; Cavanagh, Caitlin; Donley, Sachiko; Steinberg, Laurence; Frick, Paul J; Cauffman, Elizabeth

    2016-04-01

    During adolescence, youths develop attitudes about the justice system. Although there is consistent evidence that personal experiences with legal actors contribute to attitudes toward the justice system, adolescents' attitudes may also be influenced vicariously through their friends' experiences with the justice system. Using data from a sample of 1,216 first-time male adolescent offenders, the present study examines how attitudes toward the justice system develop over 24 months following the adolescent's first arrest. Even after accounting for personal justice system experiences, including self-reported offending, time on the streets, and contacts with the police, results indicate that adolescents with friends who were arrested report more negative attitudes toward the justice system than those without friends who were arrested. Further, experiencing a friend's arrest has a larger impact on the attitudes of youths who are experiencing it for the first time. We provide evidence that attitudes toward the justice system are a product of accumulated social experiences-both personal and vicarious-with the justice system. (PsycINFO Database Record PMID:26595702

  16. [Heart and vascular surgery interventions with hypothermic circulatory arrest in adults].

    Science.gov (United States)

    Kipfer, B; Leupi, F; Althaus, U

    1990-10-01

    In the period between 1981 and 1988, 51 patients were operated on the thoracic aorta using the hypothermic circulatory arrest technique. 31 patients had a dissection of the thoracic aorta, in 16 cases, an aneurysm was the reason for the intervention. In addition, we used the hypothermic circulatory arrest for a thrombectomy in the aortic arch and two mitral-valve replacements. The following operations were performed: 14 x composite graft, 19 x supracoronar prosthesis (6 x with aortic valve replacement, 3 x with partial replacement of aortic arch), 17 operations were performed either for aortic arch or aorta descendens replacement. In our retrospective study, 7 courses were fata (14%), 3 patients had complications with residuals. Compared with a group of 105 patients operated on the thoracic aorta in the same period without circulatory arrest, we found no difference with regard to the lethality and morbidity. We conclude that the hypothermic circulatory arrest is a safe technique for selected problems in cardiovascular surgery in adults. PMID:2074178

  17. A case of sinus arrest caused by opening the mouth under general anesthesia.

    OpenAIRE

    Seo, K; Takayama, H.; Araya, Y.; Miura, K; Someya, G.

    1994-01-01

    We report a case in which transient sinus arrest was observed under general anesthesia. This was associated with opening the mouth and was thought to be caused by a trigeminovagal reflex. The reflex was interrupted by blocking bilaterally the third division of trigeminal nerve.

  18. Total triterpenoids from Ganoderma Lucidum suppresses prostate cancer cell growth by inducing growth arrest and apoptosis.

    Science.gov (United States)

    Wang, Tao; Xie, Zi-ping; Huang, Zhan-sen; Li, Hao; Wei, An-yang; Di, Jin-ming; Xiao, Heng-jun; Zhang, Zhi-gang; Cai, Liu-hong; Tao, Xin; Qi, Tao; Chen, Di-ling; Chen, Jun

    2015-10-01

    In this study, one immortalized human normal prostatic epithelial cell line (BPH) and four human prostate cancer cell lines (LNCaP, 22Rv1, PC-3, and DU-145) were treated with Ganoderma Lucidum triterpenoids (GLT) at different doses and for different time periods. Cell viability, apoptosis, and cell cycle were analyzed using flow cytometry and chemical assays. Gene expression and binding to DNA were assessed using real-time PCR and Western blotting. It was found that GLT dose-dependently inhibited prostate cancer cell growth through induction of apoptosis and cell cycle arrest at G1 phase. GLT-induced apoptosis was due to activation of Caspases-9 and -3 and turning on the downstream apoptotic events. GLT-induced cell cycle arrest (mainly G1 arrest) was due to up-regulation of p21 expression at the early time and down-regulation of cyclin-dependent kinase 4 (CDK4) and E2F1 expression at the late time. These findings demonstrate that GLT suppresses prostate cancer cell growth by inducing growth arrest and apoptosis, which might suggest that GLT or Ganoderma Lucidum could be used as a potential therapeutic drug for prostate cancer.

  19. Sudden cardiac arrest as a presentation of Brugada syndrome unmasked by thyroid storm

    NARCIS (Netherlands)

    Korte, Anna K M; Derde, Lennie; van Wijk, Jeroen; Tjan, David H

    2015-01-01

    An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was treated with radioactive iodine. Recently, block-a

  20. Willingness to Perform Chest Compression Only in Witnessed Cardiac Arrest Victims versus Cardiopulmonary Resuscitation in Iran

    Directory of Open Access Journals (Sweden)

    Nesreen Yaghmour

    2015-03-01

    Full Text Available Background: Performing immediate bystander Cardio Pulmonary Resuscitation (CPR is the most important factor that determines survival from cardiac arrest. Recommended mouth to mouth ventilation maneuver during CPR has led to lower rate of CPR performance in the population. Objectives: The present survey aimed to evaluate the willingness of nurses at Shiraz University of Medical Sciences for performing CPR versus chest-compression-only CPR. Patients and Methods: During a CPR course, we performed a survey on 25 nurses from Shiraz University of Medical Sciences, Iran. This survey included age and gender of the participants. In the first question, they were asked about their willingness to perform CPR with mouth to mouth breathing for witnessed cardiac arrest victims. In the second question, they were asked about their willingness to perform chest compression only for cardiac arrest victims. Results: Among the participating nurses, 96% were female with a mean age of 31 years. Only 40% were willing to perform CPR that requires mouth to mouth ventilation. On the other hand, 92% were willing to perform chest compression only without mouth to mouth ventilation. The mean age of the nurses who would do CPR was lower compared to those who would not. Conclusions: In this survey, we demonstrated that eliminating mouth to mouth ventilation maneuver could lead to markedly higher willingness to perform CPR for witnessed cardiac arrest victims in CPR trained nursing personnel. Our study is in agreement with other studies advocating that chest-compression-only CPR could lead to higher bystander resuscitation efforts.

  1. 39 CFR 230.4 - Arrest and investigative powers of criminal investigators.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Arrest and investigative powers of criminal... criminal investigators. (a) Under the authority of 18 U.S.C. 3061, criminal investigators employed by the...) Carry firearms; and (5) Make seizures of property as provided by law. (b) Administrative subpoenas...

  2. The impact of therapeutic hypothermia on neurological function and quality of life after cardiac arrest

    DEFF Research Database (Denmark)

    Bro-Jeppesen, John; Kjaergaard, Jesper; Horsted, Tina I;

    2008-01-01

    AIMS: To assess the impact of therapeutic hypothermia on cognitive function and quality of life in comatose survivors of out of Hospital Cardiac arrest (OHCA). METHODS: We prospectively studied comatose survivors of OHCA consecutively admitted in a 4-year period. Therapeutic hypothermia was imple...

  3. Long-term neuropsychological outcomes in children and adolescents after cardiac arrest

    NARCIS (Netherlands)

    L. van Zellem (Lennart); C.M.P. Buysse (Corinne); M.J. Madderom (Marlous); J.S. Legerstee (Jeroen); F.K. Aarsen (Femke); D. Tibboel (Dick); E.M.W.J. Utens (Elisabeth)

    2015-01-01

    textabstractPurpose: Research into neuropsychological functioning of survivors of cardiac arrest (CA) in childhood is scarce. We sought to assess long-term neuropsychological functioning in children and adolescents surviving CA. Methods: Neuropsychological follow-up study involving all consecutive c

  4. Adverse Childhood Experiences and Arrest Patterns in a Sample of Sexual Offenders.

    Science.gov (United States)

    Levenson, Jill S; Socia, Kelly M

    2016-06-01

    Developmental psychopathology theories suggest that childhood adversity can contribute to antisocial conduct and delinquent activities. The purpose of this study was to explore the influence of adverse childhood experiences (ACE) on arrest patterns in a sample of sexual offenders (N = 740). Higher ACE scores were associated with a variety of arrest outcomes, indicating that the accumulation of early trauma increased the likelihood of versatility and persistence of criminal behavior. Rapists of adults had higher ACE scores, lower levels of specialization, and higher levels of persistence than sex offenders with minor victims only. Child sexual abuse, emotional neglect, and domestic violence in the childhood home were significant predictors of a higher number of sex crime arrests. For measures of nonsexual arrests and criminal versatility, it was the household dysfunction factors-substance abuse, unmarried parents, and incarceration of a family member-that were predictive, suggesting that family dysfunction and a chaotic home environment contributed significantly to increased risk of general criminal behavior. Sex offenders inspire little sympathy in our society but may be among those most in need of trauma-informed models of treatment that recognize the influence of early adversity on maladaptive schema and self-regulation deficits related to criminal behavior. PMID:25711615

  5. A synthetic circuit for selectively arresting daughter cells to create aging populations.

    Science.gov (United States)

    Afonso, Bruno; Silver, Pamela A; Ajo-Franklin, Caroline M

    2010-05-01

    The ability to engineer genetic programs governing cell fate will permit new safeguards for engineered organisms and will further the biological understanding of differentiation and aging. Here, we have designed, built and implemented a genetic device in the budding yeast Saccharomyces cerevisiae that controls cell-cycle progression selectively in daughter cells. The synthetic device was built in a modular fashion by combining timing elements that are coupled to the cell cycle, i.e. cell-cycle specific promoters and protein degradation domains, and an enzymatic domain which conditionally confers cell arrest. Thus, in the presence of a drug, the device is designed to arrest growth of only newly-divided daughter cells in the population. Indeed, while the engineered cells grow normally in the absence of drug, with the drug the engineered cells display reduced, linear growth on the population level. Fluorescence microscopy of single cells shows that the device induces cell arrest exclusively in daughter cells and radically shifts the age distribution of the resulting population towards older cells. This device, termed the 'daughter arrester', provides a blueprint for more advanced devices that mimic developmental processes by having control over cell growth and death.

  6. Response interval is important for survival until admission after prehospital cardiac arrest

    DEFF Research Database (Denmark)

    Do, Hien Quoc; Nielsen, Søren Loumann; Rasmussen, Lars Simon

    2010-01-01

    An increasing distance to the nearest hospital must be expected as a result of centralization of acute care at a small number of hospitals. This may have important consequences in emergency situations, such as prehospital or out-of-hospital cardiac arrest (OHCA) where the aim is to obtain return...

  7. Total triterpenoids from Ganoderma Lucidum suppresses prostate cancer cell growth by inducing growth arrest and apoptosis.

    Science.gov (United States)

    Wang, Tao; Xie, Zi-ping; Huang, Zhan-sen; Li, Hao; Wei, An-yang; Di, Jin-ming; Xiao, Heng-jun; Zhang, Zhi-gang; Cai, Liu-hong; Tao, Xin; Qi, Tao; Chen, Di-ling; Chen, Jun

    2015-10-01

    In this study, one immortalized human normal prostatic epithelial cell line (BPH) and four human prostate cancer cell lines (LNCaP, 22Rv1, PC-3, and DU-145) were treated with Ganoderma Lucidum triterpenoids (GLT) at different doses and for different time periods. Cell viability, apoptosis, and cell cycle were analyzed using flow cytometry and chemical assays. Gene expression and binding to DNA were assessed using real-time PCR and Western blotting. It was found that GLT dose-dependently inhibited prostate cancer cell growth through induction of apoptosis and cell cycle arrest at G1 phase. GLT-induced apoptosis was due to activation of Caspases-9 and -3 and turning on the downstream apoptotic events. GLT-induced cell cycle arrest (mainly G1 arrest) was due to up-regulation of p21 expression at the early time and down-regulation of cyclin-dependent kinase 4 (CDK4) and E2F1 expression at the late time. These findings demonstrate that GLT suppresses prostate cancer cell growth by inducing growth arrest and apoptosis, which might suggest that GLT or Ganoderma Lucidum could be used as a potential therapeutic drug for prostate cancer. PMID:26489631

  8. Pharmacotherapy and hospital admissions before out-of-hospital cardiac arrest: a nationwide study

    DEFF Research Database (Denmark)

    Weeke, Peter; Folke, Fredrik; Gislason, Gunnar H;

    2010-01-01

    For out-of-hospital cardiac arrest (OHCA) to be predicted and prevented, it is imperative the healthcare system has access to those vulnerable before the event occurs. We aimed to determine the extent of contact to the healthcare system before OHCA....

  9. Glucose restriction induces transient G2 cell cycle arrest extending cellular chronological lifespan.

    Science.gov (United States)

    Masuda, Fumie; Ishii, Mahiro; Mori, Ayaka; Uehara, Lisa; Yanagida, Mitsuhiro; Takeda, Kojiro; Saitoh, Shigeaki

    2016-01-01

    While glucose is the fundamental source of energy in most eukaryotes, it is not always abundantly available in natural environments, including within the human body. Eukaryotic cells are therefore thought to possess adaptive mechanisms to survive glucose-limited conditions, which remain unclear. Here, we report a novel mechanism regulating cell cycle progression in response to abrupt changes in extracellular glucose concentration. Upon reduction of glucose in the medium, wild-type fission yeast cells undergo transient arrest specifically at G2 phase. This cell cycle arrest is dependent on the Wee1 tyrosine kinase inhibiting the key cell cycle regulator, CDK1/Cdc2. Mutant cells lacking Wee1 are not arrested at G2 upon glucose limitation and lose viability faster than the wild-type cells under glucose-depleted quiescent conditions, suggesting that this cell cycle arrest is required for extension of chronological lifespan. Our findings indicate the presence of a novel cell cycle checkpoint monitoring glucose availability, which may be a good molecular target for cancer therapy. PMID:26804466

  10. Teenagers' High Arrest Rates: Features of Young Age or Youth Poverty?

    Science.gov (United States)

    Males, Mike A.; Brown, Elizabeth A.

    2014-01-01

    The association of more crime with youthful age is widely accepted in social science. However, a literature search revealed no studies of the age-crime relationship that controlled for young ages' economic disadvantage. This research gap is addressed using the California Criminal Justice Statistics Center's arrest detail and Census…

  11. Airway Delivery of Mesenchymal Stem Cells Prevents Arrested Alveolar Growth in Neonatal Lung Injury in Rats

    OpenAIRE

    van Haaften, Timothy; Byrne, Roisin; Bonnet, Sebastien; Rochefort, Gael Y.; Akabutu, John; Bouchentouf, Manaf; Rey-Parra, Gloria J.; Galipeau, Jacques; Haromy, Alois; Eaton, Farah; Chen, Ming; Hashimoto, Kyoko; Abley, Doris; Korbutt, Greg; Archer, Stephen L.

    2009-01-01

    Rationale: Bronchopulmonary dysplasia (BPD) and emphysema are characterized by arrested alveolar development or loss of alveoli; both are significant global health problems and currently lack effective therapy. Bone marrow–derived mesenchymal stem cells (BMSCs) prevent adult lung injury, but their therapeutic potential in neonatal lung disease is unknown.

  12. F-MARC: promoting the prevention and management of sudden cardiac arrest in football.

    Science.gov (United States)

    Kramer, Efraim Benjamin; Dvorak, J; Schmied, C; Meyer, T

    2015-05-01

    Sudden cardiac death is the most common cause of unnatural death in football. To prevent and urgently manage sudden cardiac arrest on the football field-of-play, F-MARC (FIFA Medical and Research Centre) has been fully committed to a programme of research, education, standardisation and practical implementation. This strategy has detected football players at medical risk during mandatory precompetition medical assessments. Additionally, FIFA has (1) sponsored internationally accepted guidelines for the interpretation of an athlete's ECG, (2) developed field-of-play-specific protocols for the recognition, response, resuscitation and removal of a football player having sudden cardiac arrest and (3) introduced and distributed the FIFA medical emergency bag which has already resulted in the successful resuscitation of a football player who had a sudden cardiac arrest on the field-of-play. Recently FIFA, in association with the Institute of Sports and Preventive Medicine in Saarbrücken, Germany, established a worldwide Sudden Death Registry with a view to documenting fatal events on the football field-of-play. These activities by F-MARC are testimony to FIFA's continued commitment to minimising sudden cardiac arrest while playing football. PMID:25878076

  13. Dux4 induces cell cycle arrest at G1 phase through upregulation of p21 expression

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Hongliang; Wang, Zhaoxia; Jin, Suqin; Hao, Hongjun [Department of Neurology, Peking University First Hospital, Beijing 100034 (China); Zheng, Lemin [The Institute of Cardiovascular Sciences, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Sciences of Education Ministry, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides of Health Ministry, Beijing 100191 (China); Zhou, Boda [The Department of Cardiology, Peking University Third Hospital, Beijing 100191 (China); Zhang, Wei; Lv, He [Department of Neurology, Peking University First Hospital, Beijing 100034 (China); Yuan, Yun, E-mail: yuanyun2002@sohu.com [Department of Neurology, Peking University First Hospital, Beijing 100034 (China)

    2014-03-28

    Highlights: • Dux4 induced TE671 cell proliferation defect and G1 phase arrest. • Dux4 upregulated p21 expression without activating p53. • Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. • Sp1 binding site was required for Dux4-induced p21 promoter activation. - Abstract: It has been implicated that Dux4 plays crucial roles in development of facioscapulohumeral dystrophy. But the underlying myopathic mechanisms and related down-stream events of this retrogene were far from clear. Here, we reported that overexpression of Dux4 in a cell model TE671 reduced cell proliferation rate, and increased G1 phase accumulation. We also determined the impact of Dux4 on p53/p21 signal pathway, which controls the checkpoint in cell cycle progression. Overexpression of Dux4 increased p21 mRNA and protein level, while expression of p53, phospho-p53 remained unchanged. Silencing p21 rescued Dux4 mediated proliferation defect and cell cycle arrest. Furthermore, we demonstrated that enhanced Dux4 expression increased p21 promoter activity and elevated expression of Sp1 transcription factor. Mutation of Sp1 binding site decreased dux4 induced p21 promoter activation. Chromatin immunoprecipitation (ChIP) assays confirmed the Dux4-induced binding of Sp1 to p21 promoter in vivo. These results suggest that Dux4 might induce proliferation inhibition and G1 phase arrest through upregulation of p21.

  14. Gene expression signature in organized and growth arrested mammaryacini predicts good outcome in breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Fournier, Marcia V.; Martin, Katherine J.; Kenny, Paraic A.; Xhaja, Kris; Bosch, Irene; Yaswen, Paul; Bissell, Mina J.

    2006-02-08

    To understand how non-malignant human mammary epithelial cells (HMEC) transit from a disorganized proliferating to an organized growth arrested state, and to relate this process to the changes that occur in breast cancer, we studied gene expression changes in non-malignant HMEC grown in three-dimensional cultures, and in a previously published panel of microarray data for 295 breast cancer samples. We hypothesized that the gene expression pattern of organized and growth arrested mammary acini would share similarities with breast tumors with good prognoses. Using Affymetrix HG-U133A microarrays, we analyzed the expression of 22,283 gene transcripts in two HMEC cell lines, 184 (finite life span) and HMT3522 S1 (immortal non-malignant), on successive days post-seeding in a laminin-rich extracellular matrix assay. Both HMECs underwent growth arrest in G0/G1 and differentiated into polarized acini between days 5 and 7. We identified gene expression changes with the same temporal pattern in both lines. We show that genes that are significantly lower in the organized, growth arrested HMEC than in their proliferating counterparts can be used to classify breast cancer patients into poor and good prognosis groups with high accuracy. This study represents a novel unsupervised approach to identifying breast cancer markers that may be of use clinically.

  15. 4-Formylaminooxyvinylglycine, an Herbicidal Germination-Arrest Factor (GAF) from Pseudomonas Rhizosphere Bacteria

    Science.gov (United States)

    A new oxyvinylglycine has been identified as a naturally occurring herbicide that irreversibly arrests germination of the seeds of grassy weeds; such as annual bluegrass (Poa annua), without significantly affecting the growth of established grass seedlings and mature plants, or germination of the se...

  16. Active explosion protection by lightning arresting systems; Aktiver Explosionsschutz durch Blitzschutz

    Energy Technology Data Exchange (ETDEWEB)

    Gmelch, L.; Pfister, N. [Dehn und Soehne GmbH und Co.KG, Neumarkt (Germany)

    2008-07-01

    A good active explosion protection can minimize the ignition risk. To achieve this, lightning has to be taken into account as a potential ignition source when protection measures are taken. So lightning arresting components, proved according to the most advanced product standards, help to realize a good active protection against explosion. (orig./GL)

  17. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

    DEFF Research Database (Denmark)

    Suzuki, Harukazu; Forrest, Alistair R R; van Nimwegen, Erik;

    2009-01-01

    Using deep sequencing (deepCAGE), the FANTOM4 study measured the genome-wide dynamics of transcription-start-site usage in the human monocytic cell line THP-1 throughout a time course of growth arrest and differentiation. Modeling the expression dynamics in terms of predicted cis-regulatory sites...

  18. Out-of-Hospital Perimortem Cesarean Section as Resuscitative Hysterotomy in Maternal Posttraumatic Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Francesca Gatti

    2014-01-01

    Full Text Available The optimal treatment of a severe hemodynamic instability from shock to cardiac arrest in late term pregnant women is subject to ongoing studies. However, there is an increasing evidence that early “separation” between the mother and the foetus may increase the restoration of the hemodynamic status and, in the cardiac arrest setting, it may raise the likelihood of a return of spontaneous circulation (ROSC in the mother. This treatment, called Perimortem Cesarean Section (PMCS, is now termed as Resuscitative Hysterotomy (RH to better address the issue of an early Cesarean section (C-section. This strategy is in contrast with the traditional treatment of cardiac arrest characterized by the maintenance of cardiopulmonary resuscitation (CPR maneuvers without any emergent surgical intervention. We report the case of a prehospital perimortem delivery by Caesarean (C section of a foetus at 36 weeks of gestation after the mother’s traumatic cardiac arrest. Despite the negative outcome of the mother, the choice of performing a RH seems to represent up to date the most appropriate intervention to improve the outcome in both mother and foetus.

  19. Indicators for intervention during the expulsive second-stage arrest of labour

    NARCIS (Netherlands)

    E. Leushuis; M. Tromp; A.C.J. Ravelli; A.M. van Huis; B.W. Mol; G.H.A. Visser; J.A.M. van der Post

    2009-01-01

    Objective To identify antepartum and intrapartum indicators of obstetric interventions during the expulsive second-stage arrest of labour. Design Retrospective cohort study. Setting The Netherlands. Population A cohort of 389 086 women with singleton, cephalic, term, live-birth deliveries from 2002

  20. INVESTIGATION OF FUEL CHEMISTRY AND BED PERFORMANCE IN A FLUIDIZED BED BLACK LIQUOR STEAM REFORMER

    Energy Technology Data Exchange (ETDEWEB)

    Kevin Whitty

    2003-12-01

    The University of Utah project ''Investigation of Fuel Chemistry and Bed Performance in a Fluidized Bed Black Liquor Steam Reformer'' (DOE award number DE-FC26-02NT41490) was developed in response to a solicitation for projects to provide technical support for black liquor and biomass gasification. The primary focus of the project is to provide support for a DOE-sponsored demonstration of MTCI's black liquor steam reforming technology at Georgia-Pacific's paper mill in Big Island, Virginia. A more overarching goal is to improve the understanding of phenomena that take place during low temperature black liquor gasification. This is achieved through five complementary technical tasks: (1) construction of a fluidized bed black liquor gasification test system, (2) investigation of bed performance, (3) evaluation of product gas quality, (4) black liquor conversion analysis and modeling and (5) computational modeling of the Big Island gasifier. Four experimental devices have been constructed under this project. The largest facility, which is the heart of the experimental effort, is a pressurized fluidized bed gasification test system. The system is designed to be able to reproduce conditions near the black liquor injectors in the Big Island steam reformer, so the behavior of black liquor pyrolysis and char gasification can be quantified in a representative environment. The gasification test system comprises five subsystems: steam generation and superheating, black liquor feed, fluidized bed reactor, afterburner for syngas combustion and a flue gas cooler/condenser. The three-story system is located at University of Utah's Industrial Combustion and Gasification Research Facility, and all resources there are available to support the research.