WorldWideScience

Sample records for array format 20khz

  1. 20 kHz main inverter unit. [for space station power supplies

    Science.gov (United States)

    Hussey, S.

    1989-01-01

    A proof-of-concept main inverter unit has demonstrated the operation of a pulse-width-modulated parallel resonant power stage topology as a 20-kHz ac power source driver, showing simple output regulation, parallel operation, power sharing and short-circuit operation. The use of a two-stage dc input filter controls the electromagnetic compatibility (EMC) characteristics of the dc power bus, and the use of an ac harmonic trap controls the EMC characteristics of the 20-kHz ac power bus.

  2. Plasma antennas driven by 5–20 kHz AC power supply

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Jiansen, E-mail: 67093058@qq.com; Chen, Yuli; Sun, Yang; Wu, Huafeng; Liu, Yue; Yuan, Qiumeng [Merchant Marine College, Shanghai Maritime University, Shanghai, 201306 (China)

    2015-12-15

    The experiments described in this work were performed with the aim of introducing a new plasma antenna that was excited by a 5–20 kHz alternating current (AC) power supply, where the antenna was transformed into a U-shape. The results show that the impedance, voltage standing-wave ratio (VSWR), radiation pattern and gain characteristics of the antenna can be controlled rapidly by varying not only the discharge power, but also by varying the discharge frequency in the range from 5 to 20 kHz. When the discharge frequency is adjusted from 10 to 12 kHz, the gain is higher within a relatively broad frequency band and the switch-on time is less than 1 ms when the discharge power is less than 5 W, meaning that the plasma antenna can be turned on and off rapidly.

  3. Characterization of the 20 kHz transient MHD burst at the fast U-3M confinement modification stage

    Science.gov (United States)

    Dreval, M. B.; Pavlichenko, R. O.; Shapoval, A. M.; Pashnev, V. K.; Sorokovoy, E. L.; Slavnyj, A. S.; Beletskii, A. A.; Mironov, Yu K.; Romanov, V. S.; Kulaga, A. E.; Zamanov, N. V.

    2018-05-01

    In the URAGAN-3M (U-3M) torsatron the low-frequency transient 20–30 kHz mode is observed during the plasma confinement transition that occurs at a plasma current value of about 1 kA. The burst of this mode is always accompanied by the fast jump of the Alfvén eigenmode frequency. The transient 20–30 kHz mode contains two parts. The non-rotating part of the mode has higher amplitude and is localized in the stochastic region of the plasma. It is observed only in the vicinity of the radio-frequency antenna used for plasma production and does not propagate along the torus because of fast losses. Its high amplitude indicates that the major part of the 20–30 kHz mode is excited in the stochastic region near the antenna. In contrast, the second rotating part of the mode is localized everywhere along the torus near the plasma edge (ρ = 0.8–1). This is the n/m = 1/2 mode that rotates in the electron diamagnetic direction. It is observed in different toroidal cross-sections by various diagnostics (magnetic probe array, optics, Langmuir probe). Appearance of the 1/2 rational surface at the stochastic magnetic field line region near the plasma edge at 1 kA plasma current stage can be responsible for the mode generation. Modification of electron component gradients in the mode generation region near the antenna and the drop of the fast ion concentration (above 1 keV) in this region are observed simultaneously with the mode generation. The mode can be exited by the strong transient plasma gradients generated in the vicinity of the rational surface by the antenna.

  4. 20 kHz, 25 kVA node power transformer

    Science.gov (United States)

    Hussey, S.

    1989-01-01

    The electrical and mechanical design information and the electrical and thermal testing performed on the 440-208-V rms, 20-kHz, 25-kVa prototype node transformer are summarized. The calculated efficiency of the node transformer is 99.3 percent based on core loss and copper loss test data, and its maximum calculated load regulation is 0.7 percent. The node transformer has a weight of 19.7 lb and has a power density of 0.8 lb/kW. The hot-spot temperature rise is estimated to be 33 C above the cold plate mounting base. This proof-of-concept transformer design is a viable candidate for the space station Freedom application.

  5. 1 kHz 2D Visual Motion Sensor Using 20 × 20 Silicon Retina Optical Sensor and DSP Microcontroller.

    Science.gov (United States)

    Liu, Shih-Chii; Yang, MinHao; Steiner, Andreas; Moeckel, Rico; Delbruck, Tobi

    2015-04-01

    Optical flow sensors have been a long running theme in neuromorphic vision sensors which include circuits that implement the local background intensity adaptation mechanism seen in biological retinas. This paper reports a bio-inspired optical motion sensor aimed towards miniature robotic and aerial platforms. It combines a 20 × 20 continuous-time CMOS silicon retina vision sensor with a DSP microcontroller. The retina sensor has pixels that have local gain control and adapt to background lighting. The system allows the user to validate various motion algorithms without building dedicated custom solutions. Measurements are presented to show that the system can compute global 2D translational motion from complex natural scenes using one particular algorithm: the image interpolation algorithm (I2A). With this algorithm, the system can compute global translational motion vectors at a sample rate of 1 kHz, for speeds up to ±1000 pixels/s, using less than 5 k instruction cycles (12 instructions per pixel) per frame. At 1 kHz sample rate the DSP is 12% occupied with motion computation. The sensor is implemented as a 6 g PCB consuming 170 mW of power.

  6. Precision Measurements of Wind Turbine Noise using a Large Aperture Microphone Array

    DEFF Research Database (Denmark)

    Bradley, Stuart; Mikkelsen, Torben Krogh; Hünerbein, Sabine Von

    2016-01-01

    Experiments are described with a large microphone array (40 m scale) recording wind turbine noise. The array comprised 42 purpose-designed low-noise microphones simultaneously sampled at 20 kHz. Very high quality, fast, meteorological profile data was available from nearby 80 m masts and from the...

  7. Computer simulation of a 20-kHz power system for advanced launch systems

    Science.gov (United States)

    Sudhoff, S. D.; Wasynczuk, O.; Krause, P. C.; Kenny, B. H.

    1993-01-01

    The performance of two 20-kHz actuator power systems being built for an advanced launch system are evaluated for typical launch senario using an end-to-end system simulation. Aspects of system performance ranging from the switching of the power electronic devices to the vehicle aerodynamics are represented in the simulation. It is shown that both systems adequately stabilize the vehicle against a wind gust during launch. However, it is also shown that in both cases there are bus voltage and current fluctuations which make system power quality a concern.

  8. 90 days bioassay in sprague-dawley rats exposed to 20KHz magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung-Ho [College of Veterinary Medicine, Chonnam National Univ. Kwangju (Korea, Republic of); Song, Ji-Eun; Lee, Yun-Sil [Korea Cancer Center Hospital, Seoul (Korea, Republic of); Pack, Jeong-Ki [ETRI, Daejon (Korea, Republic of); Yoo, Done-SIk [College of Engineering, Daejon (Korea, Republic of)

    2002-07-01

    Sprague Dawley rats (20 rats/group [10 males, 10 females] in sham and magnetic field exposed groups) were exposed in carrousel irradiator to an 20 KHz magnetic field for 8 hrs/day, 5 days/week, for 90 days. Urine analysis (pH, SG, protein, ketone body, RBC, WBC, glucose, bilirubin, and urobilinogen), blood analysis (WBC, RBC, HGB; henoglubin concentration, HCT; hematocrit, MCV; mean corpuscular volume, MCH; mean corpuscular hemoglobin, MCHC; mean corpuscular hemoglobin concentration, and PLT; platelet or thrombocyte count), blood biochemistry (total protein, blood urea nitrogen, creatinine, glucose, total bilirubin, total cholesterol, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lactate dehydrogenase), histopathological analysis for organs such as liver, kidney, testis, ovary, spleen, brain, heart, and lung were performed. When compared to the sham control rats, there were no significant differences in above analysis of magnetic field exposed rats. From the results, there were no significant differences between control and exposed fetus.

  9. Shallow water acoustic backscatter and reverberation measurements using a 68-kHz cylindrical array

    Science.gov (United States)

    Gallaudet, Timothy Cole

    2001-10-01

    The characterization of high frequency, shallow water acoustic backscatter and reverberation is important because acoustic systems are used in many scientific, commercial, and military applications. The approach taken is to use data collected by the Toroidal Volume Search Sonar (TVSS), a 68 kHz multibeam sonar capable of 360° imaging in a vertical plane perpendicular to its direction of travel. With this unique capability, acoustic backscatter imagery of the seafloor, sea surface, and horizontal and vertical planes in the volume are constructed from data obtained in 200m deep waters in the Northeastern Gulf of Mexico when the TVSS was towed 78m below the surface, 735m astern of a towship. The processed imagery provide a quasi-synoptic characterization of the spatial and temporal structure of boundary and volume acoustic backscatter and reverberation. Diffraction, element patterns, and high sidelobe levels are shown to be the most serious problems affecting cylindrical arrays such as the TVSS, and an amplitude shading method is presented for reducing the peak sidelobe levels of irregular-line and non-coplanar arrays. Errors in the towfish's attitude and motion sensor, and irregularities in the TVSS's transmitted beampattern produce artifacts in the TVSS-derived bathymetry and seafloor acoustic backscatter imagery. Correction strategies for these problems are described, which are unique in that they use environmental information extracted from both ocean boundaries. Sea surface and volume acoustic backscatter imagery are used to explore and characterize the structure of near-surface bubble clouds, schooling fish, and zooplankton. The simultaneous horizontal and vertical coverage provided by the TVSS is shown to be a primary advantage, motivating further use of multibeam sonars in these applications. Whereas boundary backscatter fluctuations are well described by Weibull, K, and Rayleigh mixture probability distributions, those corresponding to volume backscatter are

  10. Generating an AC amplitude magnetic flux density value up to 150 μT at a frequency up to 100 kHz

    Science.gov (United States)

    Ulvr, Michal; Polonský, Jakub

    2017-05-01

    AC magnetic field analyzers with a triaxial coil probe are widely used by health and safety professionals, in manufacturing, and in service industries. For traceable calibration of these analyzers, it is important to be able to generate a stable, homogeneous reference AC magnetic flux density (MFD). In this paper, the generating of AC amplitude MFD value of 150 μT by single-layer Helmholtz type solenoid, described in previous work, was expanded up to a frequency of 100 kHz using the effect of serial resonance. A programmable capacitor array has been developed with a range of adjustable values from 50 pF to 51225 pF. In addition, the multi-layer search coil with a nominal area turns value of 1.3m2, used for adjusting AC MFD in the solenoid, has been modified by a transimpedance amplifier for use in a wider frequency range than up to 3 kHz. The possibility of using the programmable capacitor array up to 150 kHz has also been tested. An AC amplitude MFD value of 150 μT can be generated with expanded uncertainty better than 0.6% up to 100 kHz.

  11. Introduction of a 20 kHz Nd:YVO4 laser into a hybrid quadrupole time-of-flight mass spectrometer for MALDI-MS imaging.

    Science.gov (United States)

    Trim, Paul J; Djidja, Marie-Claude; Atkinson, Sally J; Oakes, Keith; Cole, Laura M; Anderson, David M G; Hart, Philippa J; Francese, Simona; Clench, Malcolm R

    2010-08-01

    A commercial hybrid quadrupole time-of-flight mass spectrometer has been modified for high-speed matrix-assisted laser desorption ionisation (MALDI) imaging using a short-pulse optical technology Nd:YVO(4) laser. The laser operating in frequency-tripled mode (lambda = 355 nm) is capable of delivering 1.5-ns pulses of energy at up to 8 microJ at 5-10 kHz and 3 microJ at 20 kHz. Experiments to improve beam homogeneity and reduce laser speckle by mechanical vibration of the fibre-optic laser delivery system are reported along with data from trial and tissue imaging experiments using the modified instrument. The laser appeared to yield best results for MALDI-MS imaging experiments when operating at repetition rates 5-10 kHz. Combining this with raster imaging allowed images of rat brain sections to be recorded in 37 min. Similarly, images of the distribution of peptides in "on-tissue" digest experiments from tumour tissues were recorded in 1 h and 30 min rather than the 8-h acquisition time previously used. A brief investigation of targeted protein analysis/imaging by multiple reaction monitoring experiments "on-tissue" is reported. A total of 26 transitions were recorded over a 3-s cycle time and images of abundant proteins were successfully recorded.

  12. NASA Rat Acoustic Tolerance Test 1994-1995: 8 kHz, 16 kHz, 32 kHz Experiments

    Science.gov (United States)

    Mele, Gary D.; Holley, Daniel C.; Naidu, Sujata

    1996-01-01

    Adult male Sprague-Dawley rats were exposed to chronic applied sound (74 to 79 dB, SPL) with octave band center frequencies of either 8, 16 or 32 kHz for up to 60 days. Control cages had ambient sound levels of about 62 dB (SPL). Groups of rats (test vs. control; N=9 per group) were euthanized after 0. 5. 14, 30, and 60 days. On each euthanasia day, objective evaluation of their physiology and behavior was performed using a Stress Assessment Battery (SAB) of measures. In addition, rat hearing was assessed using the brain stem auditory evoked potential (BAER) method after 60 days of exposure. No statistically significant differences in mean daily food use could be attributed to the presence of the applied test sound. Test rats used 5% more water than control rats. In the 8 kHz and 32 kHz tests this amount was statistically significant(P less than .05). This is a minor difference of questionable physiological significance. However, it may be an indication of a small reaction to the constant applied sound. Across all test frequencies, day 5 test rats had 6% larger spleens than control rats. No other body or organ weight differences were found to be statistically significant with respect to the application of sound. This spleen effect may be a transient adaptive process related to adaptation to the constant applied noise. No significant test effect on differential white blood cell counts could be demonstrated. One group demonstrated a low eosinophil count (16 kHz experiment, day 14 test group). However this was highly suspect. Across all test frequencies studied, day 5 test rats had 17% fewer total leukocytes than day 5 control rats. Sound exposed test rats exhibited 44% lower plasma corticosterone concentrations than did control rats. Note that the plasma corticosterone concentration was lower in the sound exposed test animals than the control animals in every instance (frequency exposure and number of days exposed).

  13. Out-of-plane coercive field of Ni80Fe20 antidot arrays

    International Nuclear Information System (INIS)

    Gao Chunhong; Chen Ke; Lue Ling; Zhao Jianwei; Chen Peng

    2010-01-01

    The out-of-plane magnetic anisotropy and out-of-plane magnetization reversal process of nanoscale Ni 80 Fe 20 antidot arrays deposited by magnetron sputtering technique on an anodic aluminum oxide (AAO) membrane are investigated. The angular dependence of out-of-plane remanent magnetization of Ni 80 Fe 20 antidot arrays shows that the maximum remanence is in-plane and the squareness of the out-of-plane hysteresis loop follow a |cos θ| dependence. The angular dependence of out-of-plane coercivity of Ni 80 Fe 20 antidot arrays shows that the maximum coercivity lies on the surface of a cone with its symmetric axis normal to the sample plane, which indicates a transition of magnetic reversal from curling to coherent rotation when changing the angle between the applied magnetic field and the sample plane.

  14. Out-of-plane coercive field of Ni 80Fe 20 antidot arrays

    Science.gov (United States)

    Gao, Chunhong; Chen, Ke; Lü, Ling; Zhao, Jianwei; Chen, Peng

    2010-11-01

    The out-of-plane magnetic anisotropy and out-of-plane magnetization reversal process of nanoscale Ni 80Fe 20 antidot arrays deposited by magnetron sputtering technique on an anodic aluminum oxide (AAO) membrane are investigated. The angular dependence of out-of-plane remanent magnetization of Ni 80Fe 20 antidot arrays shows that the maximum remanence is in-plane and the squareness of the out-of-plane hysteresis loop follow a |cos θ| dependence. The angular dependence of out-of-plane coercivity of Ni 80Fe 20 antidot arrays shows that the maximum coercivity lies on the surface of a cone with its symmetric axis normal to the sample plane, which indicates a transition of magnetic reversal from curling to coherent rotation when changing the angle between the applied magnetic field and the sample plane.

  15. Comparing microbubble cavitation at 500 kHz and 70 kHz related to micellar drug delivery using ultrasound.

    Science.gov (United States)

    Diaz de la Rosa, Mario A; Husseini, Ghaleb A; Pitt, William G

    2013-02-01

    We have previously reported that ultrasonic drug release at 70kHz was found to correlate with the presence of subharmonic emissions. No evidence of drug release or of the subharmonic emissions were detected in experiments at 500kHz. In an attempt to understand the difference in drug release behavior between low- and mid-frequency ultrasound, a mathematical model of a bubble oscillator was developed to explore the difference in the behavior of a single 10-μm bubble under 500- and 70-kHz ultrasound. The dynamics were found to be fundamentally different; the 500-kHz bubble follows a period-doubling route to chaos while a 70-kHz bubble follows an intermittent route to chaos. We propose that this type of "intermittent subharmonic" oscillation behavior is associated with the drug release observed experimentally. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. 2- to 3-kHz continuum emissions as possible indications of global heliospheric 'breathing'

    Science.gov (United States)

    Grzedzielski, S.; Lazarus, A. J.

    1993-01-01

    The paper analyzes the main features of 2- to 3-kHz heliospheric emissions in the context of a general heliospheric 'breathing' as inferred from the Voyager 2 solar wind average ram pressure data. Triggers for the three 3-kHz emission events seen to date are suggested, and good agreement is obtained in timing and expected postshock frequency for termination shock distances of about 90 AU. It is suggested that the visibility of the individual 3-kHz events and their observed upward frequency drift are enhanced when the postulated global heliospheric expansion results in the formation of a transient, compressed external plasma barrier around the heliopause that prevents radiation escape for several months. The average termination shock distance is estimated to be in the range 80-90 AU.

  17. High-power, format-flexible, 885-nm vertical-cavity surface-emitting laser arrays

    Science.gov (United States)

    Wang, Chad; Talantov, Fedor; Garrett, Henry; Berdin, Glen; Cardellino, Terri; Millenheft, David; Geske, Jonathan

    2013-03-01

    High-power, format flexible, 885 nm vertical-cavity surface-emitting laser (VCSEL) arrays have been developed for solid-state pumping and illumination applications. In this approach, a common VCSEL size format was designed to enable tiling into flexible formats and operating configurations. The fabrication of a common chip size on ceramic submount enables low-cost volume manufacturing of high-power VCSEL arrays. This base VCSEL chip was designed to be 5x3.33 mm2, and produced up to 50 Watts of peak continuous wave (CW) power. To scale to higher powers, multiple chips can be tiled into a combination of series or parallel configurations tailored to the application driver conditions. In actively cooled CW operation, the VCSEL array chips were packaged onto a single water channel cooler, and we have demonstrated 0.5x1, 1x1, and 1x3 cm2 formats, producing 150, 250, and 500 Watts of peak power, respectively, in under 130 A operating current. In QCW operation, the 1x3 cm2 VCSEL module, which contains 18 VCSEL array chips packaged on a single water cooler, produced over 1.3 kW of peak power. In passively cooled packages, multiple chip configurations have been developed for illumination applications, producing over 300 Watts of peak power in QCW operating conditions. These VCSEL chips use a substrate-removed structure to allow for efficient thermal heatsinking to enable high-power operation. This scalable, format flexible VCSEL architecture can be applied to wavelengths ranging from 800 to 1100 nm, and can be used to tailor emission spectral widths and build high-power hyperspectral sources.

  18. Multiscale electrophysiology format: an open-source electrophysiology format using data compression, encryption, and cyclic redundancy check.

    Science.gov (United States)

    Brinkmann, Benjamin H; Bower, Mark R; Stengel, Keith A; Worrell, Gregory A; Stead, Matt

    2009-01-01

    Continuous, long-term (up to 10 days) electrophysiological monitoring using hybrid intracranial electrodes is an emerging tool for presurgical epilepsy evaluation and fundamental investigations of seizure generation. Detection of high-frequency oscillations and microseizures could provide valuable insights into causes and therapies for the treatment of epilepsy, but requires high spatial and temporal resolution. Our group is currently using hybrid arrays composed of up to 320 micro- and clinical macroelectrode arrays sampled at 32 kHz per channel with 18-bits of A/D resolution. Such recordings produce approximately 3 terabytes of data per day. Existing file formats have limited data compression capabilities, and do not offer mechanisms for protecting patient identifying information or detecting data corruption during transmission or storage. We present a novel file format that employs range encoding to provide a high degree of data compression, a three-tiered 128-bit encryption system for patient information and data security, and a 32-bit cyclic redundancy check to verify the integrity of compressed data blocks. Open-source software to read, write, and process these files are provided.

  19. Multi-pulse 20 kHz TV Thomson scattering with high spatial resolution on TEXTOR-94

    International Nuclear Information System (INIS)

    Meiden, H.J.V.D.; Barth, C.J.; Oyevaar, T.

    2001-01-01

    This article describes the first high repetition rate TVTS system in the world. It will be implemented on TEXTOR-94, with the aim to study the dynamic behaviour of meso scale plasma phenomena, like MHD modes, filaments, transport barriers and edge phenomena. To reach this, a 20 kHz intracavity laser system is combined with an ultra fast CCD camera. During one discharge of TEXTOR-94 three bursts of 40 pulses can be extracted from the laser system with a time separation of 0.5 s between the bursts. This new equipment will be implemented on the beam line and spectrometer of the present double pulse TVTS system of TEXTOR-94. The new TVTS system will be capable of producing three times 40 electron temperature- and density profiles along a laser chord of 900 mm with a spatial resolution of 7.5 mm for the full plasma diameter and 2 mm for the edge region, respectively. An observational error of 6% on T e and 3% on n e is expected for n e = 3.5x10 19 m -3 , using a laser pulse energy of typical 16 J. (author)

  20. Arabidopsis KHZ1 and KHZ2, two novel non-tandem CCCH zinc-finger and K-homolog domain proteins, have redundant roles in the regulation of flowering and senescence.

    Science.gov (United States)

    Yan, Zongyun; Jia, Jianheng; Yan, Xiaoyuan; Shi, Huiying; Han, Yuzhen

    2017-12-01

    The two novel CCCH zinc-finger and K-homolog (KH) proteins, KHZ1 and KHZ2, play important roles in regulating flowering and senescence redundantly in Arabidopsis. The CCCH zinc-finger proteins and K-homolog (KH) proteins play important roles in plant development and stress responses. However, the biological functions of many CCCH zinc-finger proteins and KH proteins remain uncharacterized. In Arabidopsis, KHZ1 and KHZ2 are characterized as two novel CCCH zinc-finger and KH domain proteins which belong to subfamily VII in CCCH family. We obtained khz1, khz2 mutants and khz1 khz2 double mutants, as well as overexpression (OE) lines of KHZ1 and KHZ2. Compared with the wild type (WT), the khz2 mutants displayed no defects in growth and development, and the khz1 mutants were slightly late flowering, whereas the khz1 khz2 double mutants showed a pronounced late flowering phenotype. In contrast, artificially overexpressing KHZ1 and KHZ2 led to the early flowering. Consistent with the late flowering phenotype, the expression of flowering repressor gene FLC was up-regulated, while the expression of flowering integrator and floral meristem identity (FMI) genes were down-regulated significantly in khz1 khz2. In addition, we also observed that the OE plants of KHZ1 and KHZ2 showed early leaf senescence significantly, whereas the khz1 khz2 double mutants showed delayed senescence of leaf and the whole plant. Both KHZ1 and KHZ2 were ubiquitously expressed throughout the tissues of Arabidopsis. KHZ1 and KHZ2 were localized to the nucleus, and possessed both transactivation activities and RNA-binding abilities. Taken together, we conclude that KHZ1 and KHZ2 have redundant roles in the regulation of flowering and senescence in Arabidopsis.

  1. CMOS Optoelectronic Lock-In Amplifier With Integrated Phototransistor Array.

    Science.gov (United States)

    An Hu; Chodavarapu, Vamsy P

    2010-10-01

    We describe the design and development of an optoelectronic lock-in amplifier (LIA) for optical sensing and spectroscopy applications. The prototype amplifier is fabricated using Taiwan Semiconductor Manufacturing Co. complementary metal-oxide semiconductor 0.35-μm technology and uses a phototransistor array (total active area is 400 μm × 640μm) to convert the incident optical signals into electrical currents. The photocurrents are then converted into voltage signals using a transimpedance amplifier for subsequent convenient signal processing by the LIA circuitry. The LIA is optimized to be operational at 20-kHz modulation frequency but is operational in the frequency range from 13 kHz to 25 kHz. The system is tested with a light-emitting diode (LED) as the light source. The noise and signal distortions are suppressed with filters and a phase-locked loop (PLL) implemented in the LIA. The output dc voltage of the LIA is proportional to the incident optical power. The minimum measured dynamic reserve and sensitivity are 1.31 dB and 34 mV/μW, respectively. The output versus input relationship has shown good linearity. The LIA consumes an average power of 12.79 mW with a 3.3-V dc power supply.

  2. Compact 4-kHz XeF-laser with multisectional discharge gap

    Science.gov (United States)

    Andramanov, A. V.; Kabaev, S. A.; Lazhintsev, Boris V.; Nor-Arevyan, Vladimir A.; Selemir, V. D.

    2005-03-01

    An electric-discharge XeF-laser with a pulse repetition rate up to 4 kHz was developed. The laser electrode unit was made on the basis of plate-like electrodes with inductive-capacity discharge stabilization. The narrow discharge width laser energy was 3 mJ by using He/Xe/NF3 and Ne/Xe/NF3 mixtures at the total pressure of 0.8 atm and 1.2 atm, respectively. The maximum laser efficiency was ~ 0.73% The gas flow was formed with the help of a diametrical fan rotated by the direct-current motor with 80 W power. The gas velocity of 20 m/s in the interelectrode gap was achieved. The laser pulse energy for a pulse repetition rate up to 3.5...4 kHz was virtually equal to the laser pulse energy in the infrequently-repeating-pulse regime. The average output power of 12 W at the pulse repetition rate of 4 kHz was achieved. The relative root-mean-square pulse-to-pulse variation of the output energy σ = 2.5% was reached.

  3. Electromagnetic Formation Flight (EMFF) for Sparse Aperture Arrays

    Science.gov (United States)

    Kwon, Daniel W.; Miller, David W.; Sedwick, Raymond J.

    2004-01-01

    Traditional methods of actuating spacecraft in sparse aperture arrays use propellant as a reaction mass. For formation flying systems, propellant becomes a critical consumable which can be quickly exhausted while maintaining relative orientation. Additional problems posed by propellant include optical contamination, plume impingement, thermal emission, and vibration excitation. For these missions where control of relative degrees of freedom is important, we consider using a system of electromagnets, in concert with reaction wheels, to replace the consumables. Electromagnetic Formation Flight sparse apertures, powered by solar energy, are designed differently from traditional propulsion systems, which are based on V. This paper investigates the design of sparse apertures both inside and outside the Earth's gravity field.

  4. Next-Generation Microshutter Arrays for Large-Format Imaging and Spectroscopy

    Science.gov (United States)

    Moseley, Samuel; Kutyrev, Alexander; Brown, Ari; Li, Mary

    2012-01-01

    A next-generation microshutter array, LArge Microshutter Array (LAMA), was developed as a multi-object field selector. LAMA consists of small-scaled microshutter arrays that can be combined to form large-scale microshutter array mosaics. Microshutter actuation is accomplished via electrostatic attraction between the shutter and a counter electrode, and 2D addressing can be accomplished by applying an electrostatic potential between a row of shutters and a column, orthogonal to the row, of counter electrodes. Microelectromechanical system (MEMS) technology is used to fabricate the microshutter arrays. The main feature of the microshutter device is to use a set of standard surface micromachining processes for device fabrication. Electrostatic actuation is used to eliminate the need for macromechanical magnet actuating components. A simplified electrostatic actuation with no macro components (e.g. moving magnets) required for actuation and latching of the shutters will make the microshutter arrays robust and less prone to mechanical failure. Smaller-size individual arrays will help to increase the yield and thus reduce the cost and improve robustness of the fabrication process. Reducing the size of the individual shutter array to about one square inch and building the large-scale mosaics by tiling these smaller-size arrays would further help to reduce the cost of the device due to the higher yield of smaller devices. The LAMA development is based on prior experience acquired while developing microshutter arrays for the James Webb Space Telescope (JWST), but it will have different features. The LAMA modular design permits large-format mosaicking to cover a field of view at least 50 times larger than JWST MSA. The LAMA electrostatic, instead of magnetic, actuation enables operation cycles at least 100 times faster and a mass significantly smaller compared to JWST MSA. Also, standard surface micromachining technology will simplify the fabrication process, increasing

  5. Passive cavitation imaging with ultrasound arrays.

    Science.gov (United States)

    Salgaonkar, Vasant A; Datta, Saurabh; Holland, Christy K; Mast, T Douglas

    2009-12-01

    A method is presented for passive imaging of cavitational acoustic emissions using an ultrasound array, with potential application in real-time monitoring of ultrasound ablation. To create such images, microbubble emissions were passively sensed by an imaging array and dynamically focused at multiple depths. In this paper, an analytic expression for a passive image is obtained by solving the Rayleigh-Sommerfield integral, under the Fresnel approximation, and passive images were simulated. A 192-element array was used to create passive images, in real time, from 520-kHz ultrasound scattered by a 1-mm steel wire. Azimuthal positions of this target were accurately estimated from the passive images. Next, stable and inertial cavitation was passively imaged in saline solution sonicated at 520 kHz. Bubble clusters formed in the saline samples were consistently located on both passive images and B-scans. Passive images were also created using broadband emissions from bovine liver sonicated at 2.2 MHz. Agreement was found between the images and source beam shape, indicating an ability to map therapeutic ultrasound beams in situ. The relation between these broadband emissions, sonication amplitude, and exposure conditions are discussed.

  6. Shallow water acoustic backscatter and reverberation measurements using a 68-kHz cylindrical array: a dissertation

    OpenAIRE

    Gallaudet, Timothy C. (Timothy Cole), 1967-

    2001-01-01

    The characterization of high frequency, shallow water acoustic backscatter and reverberation is important because acoustic systems are used in many scientific, commercial, and military applications. The approach taken is to use data collected by the Toroidal Volume Search Sonar (TVSS), a 68 kHz multibeam sonar capable of 360 deg imaging in a vertical plane perpendicular to its direction of travel. With this unique capability, acoustic backscatter imagery of the seafloor, sea surface, and hori...

  7. The effect of ultrasound at 256 KHz on Microcystis aeruginosa, with ...

    African Journals Online (AJOL)

    2012-10-31

    Oct 31, 2012 ... for 5 min inhibits the growth of the cyanobacterium Spirulina platensis for 3 d, while a sonication with 20 kHz showed no constant effect (Hao et al., 2004). Several mechanisms were discovered by which ultrasonic treatment affects the cells, of which the collapsing of gas vacu- oles during cavitation was ...

  8. Effects on atmospherics at 6 kHz and 9 kHz recorded at Tripura during the India-Pakistan Border earthquake

    Directory of Open Access Journals (Sweden)

    S. S. De

    2010-04-01

    Full Text Available The outcome of the results of some analyses of electromagnetic emissions recorded by VLF receivers at 6 kHz and 9 kHz over Agartala, Tripura, the North-Eastern state of India (Lat. 23° N, Long. 91.4° E during the large earthquake at Muzaffarabad (Lat. 34.53° N, Long. 73.58° E at Kashmir under Pakistan have been presented here. Spiky variations in integrated field intensity of atmospherics (IFIA at 6 and 9 kHz have been observed 10 days prior (from midnight of 28 September 2005 to the day of occurrence of the earthquake on 8 October 2005 and the effect continued, decayed gradually and eventually ceased on 16 October 2005. The spikes distinctly superimposed on the ambient level with mutual separation of 2–5 min. Occurrence number of spikes per hour and total duration of their occurrence have been found remarkably high on the day of occurrence of the earthquake. The spike heights are higher at 6 kHz than at 9 kHz. The results have been explained on the basis of generation of electromagnetic radiation associated with fracture of rocks, their subsequent penetration into the Earth's atmosphere and finally their propagation between Earth-ionosphere waveguide. The present observation shows that VLF anomaly is well-confined between 6 and 9 kHz.

  9. Large-format InGaAs focal plane arrays for SWIR imaging

    Science.gov (United States)

    Hood, Andrew D.; MacDougal, Michael H.; Manzo, Juan; Follman, David; Geske, Jonathan C.

    2012-06-01

    FLIR Electro Optical Components will present our latest developments in large InGaAs focal plane arrays, which are used for low light level imaging in the short wavelength infrared (SWIR) regime. FLIR will present imaging from their latest small pitch (15 μm) focal plane arrays in VGA and High Definition (HD) formats. FLIR will present characterization of the FPA including dark current measurements as well as the use of correlated double sampling to reduce read noise. FLIR will show imagery as well as FPA-level characterization data.

  10. Out-of-plane coercive field of Ni{sub 80}Fe{sub 20} antidot arrays

    Energy Technology Data Exchange (ETDEWEB)

    Chunhong, Gao [School of Physical Science and Technology, Southwest University, Chongqing 400715 (China); Ke, Chen [Chongqing Electric Power College, Chongqing (China); Ling, Lue; Jianwei, Zhao [School of Physical Science and Technology, Southwest University, Chongqing 400715 (China); Chen Peng, E-mail: pchen@swu.edu.c [School of Physical Science and Technology, Southwest University, Chongqing 400715 (China)

    2010-11-15

    The out-of-plane magnetic anisotropy and out-of-plane magnetization reversal process of nanoscale Ni{sub 80}Fe{sub 20} antidot arrays deposited by magnetron sputtering technique on an anodic aluminum oxide (AAO) membrane are investigated. The angular dependence of out-of-plane remanent magnetization of Ni{sub 80}Fe{sub 20} antidot arrays shows that the maximum remanence is in-plane and the squareness of the out-of-plane hysteresis loop follow a |cos {theta}| dependence. The angular dependence of out-of-plane coercivity of Ni{sub 80}Fe{sub 20} antidot arrays shows that the maximum coercivity lies on the surface of a cone with its symmetric axis normal to the sample plane, which indicates a transition of magnetic reversal from curling to coherent rotation when changing the angle between the applied magnetic field and the sample plane.

  11. Spontaneous Formation of Nanopillar Arrays in Ultrathin Viscous Films: Critical Role of Thermocapillary Stresses

    Science.gov (United States)

    Troian, Sandra; Dietzel, Mathias

    2010-03-01

    Nanoscale structures manifest exceedingly large surface to volume ratios and are therefore highly susceptible to control by surface stresses. Actuation techniques which can exploit this feature provide a key strategy for construction and self-organization of large area arrays. During the past decade, several groups have reported that molten polymer nanofilms subject to an ultra-large transverse thermal gradient undergo spontaneous formation of nanopillar arrays. The prevailing explanation is that coherent interfacial reflection of acoustic phonons causes periodic modulation of the radiation pressure leading to instability and pillar growth. We demonstrate instead that thermocapillary forces play a crucial if not dominant role in the formation process due to the strong modulation of surface tension with temperature. Any nanoscale viscous film is prone to such formations, not just polymeric films. Analysis of the governing interface equation reveals the mechanism controlling the growth, spacing and symmetry of these self-assembling arrays. We discuss how these findings are being used in our laboratory to construct nanoscale components for optical and photonic applications.

  12. Design and performance of single photon APD focal plane arrays for 3-D LADAR imaging

    Science.gov (United States)

    Itzler, Mark A.; Entwistle, Mark; Owens, Mark; Patel, Ketan; Jiang, Xudong; Slomkowski, Krystyna; Rangwala, Sabbir; Zalud, Peter F.; Senko, Tom; Tower, John; Ferraro, Joseph

    2010-08-01

    ×We describe the design, fabrication, and performance of focal plane arrays (FPAs) for use in 3-D LADAR imaging applications requiring single photon sensitivity. These 32 × 32 FPAs provide high-efficiency single photon sensitivity for three-dimensional LADAR imaging applications at 1064 nm. Our GmAPD arrays are designed using a planarpassivated avalanche photodiode device platform with buried p-n junctions that has demonstrated excellent performance uniformity, operational stability, and long-term reliability. The core of the FPA is a chip stack formed by hybridizing the GmAPD photodiode array to a custom CMOS read-out integrated circuit (ROIC) and attaching a precision-aligned GaP microlens array (MLA) to the back-illuminated detector array. Each ROIC pixel includes an active quenching circuit governing Geiger-mode operation of the corresponding avalanche photodiode pixel as well as a pseudo-random counter to capture per-pixel time-of-flight timestamps in each frame. The FPA has been designed to operate at frame rates as high as 186 kHz for 2 μs range gates. Effective single photon detection efficiencies as high as 40% (including all optical transmission and MLA losses) are achieved for dark count rates below 20 kHz. For these planar-geometry diffused-junction GmAPDs, isolation trenches are used to reduce crosstalk due to hot carrier luminescence effects during avalanche events, and we present details of the crosstalk performance for different operating conditions. Direct measurement of temporal probability distribution functions due to cumulative timing uncertainties of the GmAPDs and ROIC circuitry has demonstrated a FWHM timing jitter as low as 265 ps (standard deviation is ~100 ps).

  13. Formation of discrete solitons as a function of waveguide array geometry under the well-confined mode condition

    International Nuclear Information System (INIS)

    Vergara-Betancourt, A; Martí-Panameño, E; Luis-Ramos, A; Parada-Alfonso, R

    2013-01-01

    Based on numerical techniques, in this paper, we study light propagation in two types of waveguide arrays. One array contains hexagonal cells, and the second contains honeycomb cells. The waveguides demonstrate the well-confined mode condition and possess Kerr nonlinearity. The mathematical model is based on the modified discrete nonlinear Schrödinger equation, which allows us to evaluate the influence of the array geometry on nonlinear light propagation, primarily the process of discrete soliton formation. The main conclusion involves the role of the coupling length; the greater the coupling length, the lower the power threshold required for discrete soliton formation. (paper)

  14. Formation of precise 2D Au particle arrays via thermally induced dewetting on pre-patterned substrates

    Directory of Open Access Journals (Sweden)

    Dong Wang

    2011-06-01

    Full Text Available The fabrication of precise 2D Au nanoparticle arrays over a large area is presented. The technique was based on pre-patterning of the substrate before the deposition of a thin Au film, and the creation of periodic particle arrays by subsequent dewetting induced by annealing. Two types of pre-patterned substrates were used: The first comprised an array of pyramidal pits and the second an array of circular holes. For the dewetting of Au films on the pyramidal pit substrate, the structural curvature-driven diffusion cooperates with capillarity-driven diffusion, resulting in the formation of precise 2D particle arrays for films within a structure dependent thickness-window. For the dewetting of Au films on the circular hole substrate, the periodic discontinuities in the films, induced by the deposition, can limit the diffusion paths and lead to the formation of one particle per individual separated region (holes or mesas between holes, and thus, result in the evolution of precise 2D particle arrays. The influence of the pre-patterned structures and the film thickness is analyzed and discussed. For both types of pre-patterned substrate, the Au film thickness had to be adjusted in a certain thickness-window in order to achieve the precise 2D particle arrays.

  15. Formation of precise 2D Au particle arrays via thermally induced dewetting on pre-patterned substrates

    Science.gov (United States)

    Ji, Ran

    2011-01-01

    Summary The fabrication of precise 2D Au nanoparticle arrays over a large area is presented. The technique was based on pre-patterning of the substrate before the deposition of a thin Au film, and the creation of periodic particle arrays by subsequent dewetting induced by annealing. Two types of pre-patterned substrates were used: The first comprised an array of pyramidal pits and the second an array of circular holes. For the dewetting of Au films on the pyramidal pit substrate, the structural curvature-driven diffusion cooperates with capillarity-driven diffusion, resulting in the formation of precise 2D particle arrays for films within a structure dependent thickness-window. For the dewetting of Au films on the circular hole substrate, the periodic discontinuities in the films, induced by the deposition, can limit the diffusion paths and lead to the formation of one particle per individual separated region (holes or mesas between holes), and thus, result in the evolution of precise 2D particle arrays. The influence of the pre-patterned structures and the film thickness is analyzed and discussed. For both types of pre-patterned substrate, the Au film thickness had to be adjusted in a certain thickness-window in order to achieve the precise 2D particle arrays. PMID:21977445

  16. The Effect of General Corrosion on the Guided Wave Inspection of the Pipeline

    Directory of Open Access Journals (Sweden)

    Zhang Jin Heng

    2016-01-01

    Full Text Available The guided wave method can inspect pipelines very quickly and widely. For instance, it can inspect the overall pipelines by digging several detection pits or removing part of coating material to set the array ring. However, it will make the guided wave attenuate more seriously and make the signals hard to identify when setting the array ring on the general corrosion. In this study, the wave propagation will be discussed when the general corrosion is under the array ring and the severe localized corrosion is inside the general corrosion via experiment and finite element method. The results showed that the excitation energy will be lower when the array ring set on the pipe surface with the general corrosion. By two-dimensional Fourier transform analysis, its non-uniform contact surface will increase asymmetric modal and mix signals. The energy attenuation will increase when the corrosion depth is deepened or the inspection frequency is risen. For example, the 2 mm deep general corrosion will attenuate −1.09 dB/m at 20 kHz and attenuate −3.01 dB/m at 40 kHz; the 4 mm deep general corrosion will attenuation −5.76 dB/m at 20 kHz and attenuation −23.19 dB/m at 40 kHz. However, the coherent signals which were caused by the general corrosion will decay with increasing frequency. For example, the coherent signals of 2 mm deep general corrosion are −23.67 dB at 20 kHz and −35.44 dB at 40 kHz; then, the 20 mm long and 3.5 mm deep localized corrosion which signal is −26.34 dB at 20 kHz and −26.94 dB at 40 kHz will be detected easily at high frequency. It can provide detectors to understand the impact when the array ring set on the area of general corrosion and the way to distinguish the localized corrosion which is inside the area of general corrosion.

  17. Development of HgCdTe large format MBE arrays and noise-free high speed MOVPE EAPD arrays for ground based NIR astronomy

    Science.gov (United States)

    Finger, G.; Baker, I.; Downing, M.; Alvarez, D.; Ives, D.; Mehrgan, L.; Meyer, M.; Stegmeier, J.; Weller, H. J.

    2017-11-01

    Large format near infrared HgCdTe 2Kx2K and 4Kx4K MBE arrays have reached a level of maturity which meets most of the specifications required for near infrared (NIR) astronomy. The only remaining problem is the persistence effect which is device specific and not yet fully under control. For ground based multi-object spectroscopy on 40 meter class telescopes larger pixels would be advantageous. For high speed near infrared fringe tracking and wavefront sensing the only way to overcome the CMOS noise barrier is the amplification of the photoelectron signal inside the infrared pixel by means of the avalanche gain. A readout chip for a 320x256 pixel HgCdTe eAPD array will be presented which has 32 parallel video outputs being arranged in such a way that the full multiplex advantage is also available for small sub-windows. In combination with the high APD gain this allows reducing the readout noise to the subelectron level by applying nondestructive readout schemes with subpixel sampling. Arrays grown by MOVPE achieve subelectron readout noise and operate with superb cosmetic quality at high APD gain. Efforts are made to reduce the dark current of those arrays to make this technology also available for large format focal planes of NIR instruments offering noise free detectors for deep exposures. The dark current of the latest MOVPE eAPD arrays is already at a level adequate for noiseless broad and narrow band imaging in scientific instruments.

  18. ArrayBridge: Interweaving declarative array processing with high-performance computing

    Energy Technology Data Exchange (ETDEWEB)

    Xing, Haoyuan [The Ohio State Univ., Columbus, OH (United States); Floratos, Sofoklis [The Ohio State Univ., Columbus, OH (United States); Blanas, Spyros [The Ohio State Univ., Columbus, OH (United States); Byna, Suren [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Prabhat, Prabhat [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wu, Kesheng [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Brown, Paul [Paradigm4, Inc., Waltham, MA (United States)

    2017-05-04

    Scientists are increasingly turning to datacenter-scale computers to produce and analyze massive arrays. Despite decades of database research that extols the virtues of declarative query processing, scientists still write, debug and parallelize imperative HPC kernels even for the most mundane queries. This impedance mismatch has been partly attributed to the cumbersome data loading process; in response, the database community has proposed in situ mechanisms to access data in scientific file formats. Scientists, however, desire more than a passive access method that reads arrays from files. This paper describes ArrayBridge, a bi-directional array view mechanism for scientific file formats, that aims to make declarative array manipulations interoperable with imperative file-centric analyses. Our prototype implementation of ArrayBridge uses HDF5 as the underlying array storage library and seamlessly integrates into the SciDB open-source array database system. In addition to fast querying over external array objects, ArrayBridge produces arrays in the HDF5 file format just as easily as it can read from it. ArrayBridge also supports time travel queries from imperative kernels through the unmodified HDF5 API, and automatically deduplicates between array versions for space efficiency. Our extensive performance evaluation in NERSC, a large-scale scientific computing facility, shows that ArrayBridge exhibits statistically indistinguishable performance and I/O scalability to the native SciDB storage engine.

  19. Surveying Low-Mass Star Formation with the Submillimeter Array

    Science.gov (United States)

    Dunham, Michael

    2018-01-01

    Large astronomical surveys yield important statistical information that can’t be derived from single-object and small-number surveys. In this talk I will review two recent surveys in low-mass star formation undertaken by the Submillimeter Array (SMA): a millimeter continuum survey of disks surrounding variably accreting young stars, and a complete continuum and molecular line survey of all protostars in the nearby Perseus Molecular Cloud. I will highlight several new insights into the processes by which low-mass stars gain their mass that have resulted from the statistical power of these surveys.

  20. Air puff-induced 22-kHz calls in F344 rats.

    Science.gov (United States)

    Inagaki, Hideaki; Sato, Jun

    2016-03-01

    Air puff-induced ultrasonic vocalizations in adult rats, termed "22-kHz calls," have been applied as a useful animal model to develop psychoneurological and psychopharmacological studies focusing on human aversive affective disorders. To date, all previous studies on air puff-induced 22-kHz calls have used outbred rats. Furthermore, newly developed gene targeting technologies, which are essential for further advancement of biomedical experiments using air puff-induced 22-kHz calls, have enabled the production of genetically modified rats using inbred rat strains. Therefore, we considered it necessary to assess air puff-induced 22-kHz calls in inbred rats. In this study, we assessed differences in air puff-induced 22-kHz calls between inbred F344 rats and outbred Wistar rats. Male F344 rats displayed similar total (summed) duration of air puff-induced 22 kHz vocalizations to that of male Wistar rats, however, Wistar rats emitted fewer calls of longer duration, while F344 rats emitted higher number of vocalizations of shorter duration. Additionally, female F344 rats emitted fewer air puff-induced 22-kHz calls than did males, thus confirming the existence of a sex difference that was previously reported for outbred Wistar rats. The results of this study could confirm the reliability of air puff stimulus for induction of a similar amount of emissions of 22-kHz calls in different rat strains, enabling the use of air puff-induced 22-kHz calls in inbred F344 rats and derived genetically modified animals in future studies concerning human aversive affective disorders. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. A force sensor using nanowire arrays to understand biofilm formation (Conference Presentation)

    Science.gov (United States)

    Sahoo, Prasana K.; Cavalli, Alessandro; Pelegati, Vitor B.; Murillo, Duber M.; Souza, Alessandra A.; Cesar, Carlos L.; Bakkers, Erik P. A. M.; Cotta, Monica A.

    2016-03-01

    Understanding the cellular signaling and function at the nano-bio interface can pave the way towards developing next-generation smart diagnostic tools. From this perspective, limited reports detail so far the cellular and subcellular forces exerted by bacterial cells during the interaction with abiotic materials. Nanowire arrays with high aspect ratio have been used to detect such small forces. In this regard, live force measurements were performed ex-vivo during the interaction of Xylella fastidiosa bacterial cells with InP nanowire arrays. The influence of nanowire array topography and surface chemistry on the response and motion of bacterial cells was studied in detail. The nanowire arrays were also functionalized with different cell adhesive promoters, such as amines and XadA1, an afimbrial protein of X.fastidiosa. By employing the well-defined InP nanowire arrays platform, and single cell confocal imaging system, we were able to trace the bacterial growth pattern, and show that their initial attachment locations are strongly influenced by the surface chemistry and nanoscale surface topography. In addition, we measure the cellular forces down to few nanonewton range using these nanowire arrays. In case of nanowire functionalized with XadA1, the force exerted by vertically and horizontally attached single bacteria on the nanowire is in average 14% and 26% higher than for the pristine array, respectively. These results provide an excellent basis for live-cell force measurements as well as unravel the range of forces involved during the early stages of bacterial adhesion and biofilm formation.

  2. Alarm pheromone does not modulate 22-kHz calls in male rats.

    Science.gov (United States)

    Muyama, Hiromi; Kiyokawa, Yasushi; Inagaki, Hideaki; Takeuchi, Yukari; Mori, Yuji

    2016-03-15

    Rats are known to emit a series of ultrasonic vocalizations, termed 22-kHz calls, when exposed to distressing stimuli. Pharmacological studies have indicated that anxiety mediates 22-kHz calls in distressed rats. We previously found that exposure to the rat alarm pheromone increases anxiety in rats. Therefore, we hypothesized that the alarm pheromone would increase 22-kHz calls in pheromone-exposed rats. Accordingly, we tested whether exposure to the alarm pheromone induced 22-kHz calls, as well as whether the alarm pheromone increased 22-kHz calls in response to an aversive conditioned stimulus (CS). Rats were first fear-conditioned to an auditory and contextual CS. On the following day, the rats were either exposed to the alarm pheromone or a control odor that was released from the neck region of odor-donor rats. Then, the rats were re-exposed to the aversive CS. The alarm pheromone neither induced 22-kHz calls nor increased 22-kHz calls in response to the aversive CS. In contrast, the control odor unexpectedly reduced the total number and duration of 22-kHz calls elicited by the aversive CS, as well as the duration of freezing. These results suggest that the alarm pheromone does not affect 22-kHz calls in rats. However, we may have found evidence for an appeasing olfactory signal, released from the neck region of odor-donor rats. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Cryogenic and radiation-hard asic for interfacing large format NIR/SWIR detector arrays

    Science.gov (United States)

    Gao, Peng; Dupont, Benoit; Dierickx, Bart; Müller, Eric; Verbruggen, Geert; Gielis, Stijn; Valvekens, Ramses

    2017-11-01

    For scientific and earth observation space missions, weight and power consumption is usually a critical factor. In order to obtain better vehicle integration, efficiency and controllability for large format NIR/SWIR detector arrays, a prototype ASIC is designed. It performs multiple detector array interfacing, power regulation and data acquisition operations inside the cryogenic chambers. Both operation commands and imaging data are communicated via the SpaceWire interface which will significantly reduce the number of wire goes in and out the cryogenic chamber. This "ASIC" prototype is realized in 0.18um CMOS technology and is designed for radiation hardness.

  4. Two discharge modes of a repetitive nanosecond pulsed helium glow discharge under sub-atmospheric pressure in the repetition frequency range of 20 to 600 kHz

    Science.gov (United States)

    Kikuchi, Yusuke; Maegawa, Takuya; Otsubo, Akira; Nishimura, Yoshimi; Nagata, Masayoshi; Yatsuzuka, Mitsuyasu

    2018-05-01

    Two discharge modes, α and γ, of a repetitive nanosecond pulsed helium glow discharge at a gas pressure of 10 kPa in the repetition frequency range from 20 to 600 kHz are reported for the first time. The pulsed glow discharge is produced in a pair of parallel plate metal electrodes without insertion of dielectrics. The α mode discharge is volumetrically produced in the electrode gap at a low-repetition frequency, whereas the γ mode discharge is localized at the cathode surface at a high-repetition frequency. At high-repetition frequency, the time interval between voltage pulses is shorter than the lifetime of the afterglow produced by the preceding discharge. Then, the γ mode discharge is maintained by a large number of secondary electrons emitted from the cathode exposed to high-density ions and metastable helium atoms in the afterglow. In the α mode discharge with a low-repetition frequency operation, primary electrons due to gas ionization dominate the ionization process. Thus, a large discharge voltage is needed for the excitation of the α mode discharge. It is established that the bifurcation of α-γ discharge mode, accompanied by a decrease in the discharge voltage, occurs at the high-repetition frequency of ∼120 kHz.

  5. Preparation of Janus Particles and Alternating Current Electrokinetic Measurements with a Rapidly Fabricated Indium Tin Oxide Electrode Array.

    Science.gov (United States)

    Chen, Yu-Liang; Jiang, Hong-Ren

    2017-06-23

    This article provides a simple method to prepare partially or fully coated metallic particles and to perform the rapid fabrication of electrode arrays, which can facilitate electrical experiments in microfluidic devices. Janus particles are asymmetric particles that contain two different surface properties on their two sides. To prepare Janus particles, a monolayer of silica particles is prepared by a drying process. Gold (Au) is deposited on one side of each particle using a sputtering device. The fully coated metallic particles are completed after the second coating process. To analyze the electrical surface properties of Janus particles, alternating current (AC) electrokinetic measurements, such as dielectrophoresis (DEP) and electrorotation (EROT)- which require specifically designed electrode arrays in the experimental device- are performed. However, traditional methods to fabricate electrode arrays, such as the photolithographic technique, require a series of complicated procedures. Here, we introduce a flexible method to fabricate a designed electrode array. An indium tin oxide (ITO) glass is patterned by a fiber laser marking machine (1,064 nm, 20 W, 90 to 120 ns pulse-width, and 20 to 80 kHz pulse repetition frequency) to create a four-phase electrode array. To generate the four-phase electric field, the electrodes are connected to a 2-channel function generator and to two invertors. The phase shift between the adjacent electrodes is set at either 90° (for EROT) or 180° (for DEP). Representative results of AC electrokinetic measurements with a four-phase ITO electrode array are presented.

  6. Evidence of hexatic phase formation in two-dimensional Lennard-Jones binary arrays

    International Nuclear Information System (INIS)

    Li, M.; Johnson, W.L.; Goddard, W.A. III

    1996-01-01

    We report evidence of the hexatic phase formation in Lennard-Jones binary substitutional random arrays from isothermal-isobaric molecular-dynamics simulations. The hexatic phase is analogous to those predicted in Kosterlitz-Thouless theory of melting that is characterized by short-range translational order and quasi-long-range orientational order. At the crystal to hexatic phase transition, dislocation pairs are observed to unbind into isolated dislocations. Further disordering of the hexatic phase, however, does not lead to dissociation of dislocations into disclinations. Instead, the dislocations become clustered and form dislocation networks which results in formation of amorphous phases. copyright 1996 The American Physical Society

  7. THE SPECTRAL-TIMING PROPERTIES OF UPPER AND LOWER kHz QPOs

    Energy Technology Data Exchange (ETDEWEB)

    Peille, Philippe; Barret, Didier [Université de Toulouse, UPS-OMP, IRAP, Toulouse (France); Uttley, Phil, E-mail: philippe.peille@irap.omp.eu [Anton Pannekoek Institute, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands)

    2015-10-01

    Soft lags from the emission of the lower kilohertz quasi-periodic oscillations (kHz QPOs) of neutron star low-mass X-ray binaries have been reported from 4U1608-522 and 4U1636-536. Those lags hold prospects for constraining the origin of the QPO emission. In this paper, we investigate the spectral-timing properties of both the lower and upper kHz QPOs from the neutron star binary 4U1728-34, using the entire Rossi X-Ray Timing Explorer archive on this source. We show that the lag-energy spectra of the two QPOs are systematically different: while the lower kHz QPO shows soft lags, the upper kHz QPO shows either a flat lag-energy spectrum or hard variations lagging softer variations. This suggests two different QPO-generation mechanisms. We also performed the first spectral deconvolution of the covariance spectra of both kHz QPOs. The QPO spectra are consistent with Comptonized blackbody emission, similar to the one found in the time-averaged spectrum, but with a higher seed-photon temperature, suggesting that a more compact inner region of the Comptonization layer (boundary/spreading layer, corona) is responsible for the QPO emission. Considering our results together with other recent findings, this leads us to the hypothesis that the lower kHz QPO signal is generated by coherent oscillations of the compact boundary layer region itself. The upper kHz QPO signal may then be linked to less-coherent accretion-rate variations produced in the inner accretion disk, and is then detected when they reach the boundary layer.

  8. Inherent-opening-controlled pattern formation in carbon nanotube arrays

    International Nuclear Information System (INIS)

    Huang Xiao; Zhou, Jijie J; Sansom, Elijah; Gharib, Morteza; Haur, Sow Chorng

    2007-01-01

    We have introduced inherent openings into densely packed carbon nanotube arrays to study self-organized pattern formation when the arrays undergo a wetting-dewetting treatment from nanotube tips. These inherent openings, made of circular or elongated hollows in nanotube mats, serve as dewetting centres, from where liquid recedes from. As the dewetting centres initiate dry zones and the dry zones expand, surrounding nanotubes are pulled away from the dewetting centres by liquid surface tension. Among short nanotubes, the self-organized patterns are consistent with the shape of the inherent openings, i.e. slender openings lead to elongated trench-like structures, and circular holes result in relatively round nest-like arrangements. Nanotubes in a relatively high mat are more connected, like in an elastic body, than those in a short mat. Small cracks often initialize themselves in a relatively high mat, along two or more adjacent round openings; each of the cracks evolves into a trench as liquid dries up. Self-organized pattern control with inherent openings needs to initiate the dewetting process above the nanotube tips. If there is no liquid on top, inherent openings barely enlarge themselves after the wetting-dewetting treatment

  9. Effects of the India–Pakistan border earthquake on the atmospherics at 6 kHz and 9 kHz recorded at Tripura

    Directory of Open Access Journals (Sweden)

    Sudarsan Barui

    2011-04-01

    Full Text Available The unusual variations observed in the records of the integrated field intensity of the atmospherics (IFIA at 6 kHz and 9 kHz at Agartala, Tripura, in the north-eastern state of India (latitude, 23˚ N; longitude, 91.4˚ E during the large earthquake on October 8, 2005 at Muzaffarabad (latitude, 34.53˚ N; longitude, 73.58˚ E in Kashmir in Pakistan are here analyzed. Spiky variations in the IFIA at 6 kHz and 9 kHz were observed several days previous to the day of the earthquake (from midnight, September 28, 2005. The effects persisted for some days, decayed gradually, and eventually ceased on October 31, 2005. The spikes are distinctly superimposed on the ambient level

  10. Design, development and evaluation of a resistor-based multiplexing circuit for a 20×20 SiPM array

    International Nuclear Information System (INIS)

    Wang, Zhonghai; Sun, Xishan; Lou, Kai; Meier, Joseph; Zhou, Rong; Yang, Chaowen; Zhu, Xiaorong; Shao, Yiping

    2016-01-01

    One technical challenge in developing a large-size scintillator detector with multiple Silicon Photomultiplier (SiPM) arrays is to read out a large number of detector output channels. To achieve this, different signal multiplexing circuits have been studied and applied with different performances and cost-effective tradeoffs. Resistor-based multiplexing circuits exhibit simplicity and signal integrity, but also present the disadvantage of timing shift among different channels. In this study, a resistor-based multiplexing circuit for a large-sized SiPM array readout was developed and evaluated by simulation and experimental studies. Similarly to a multiplexing circuit used for multi-anode PMT, grounding and branching resistors were connected to each SiPM output channel. The grounding resistor was used to simultaneously reduce the signal crosstalk among different channels and to improve timing performance. Both grounding and branching resistor values were optimized to maintain a balanced performance of the event energy, timing, and positioning. A multiplexing circuit was implemented on a compact PCB and applied for a flat-panel detector which consisted of a 32×32 LYSO scintillator crystals optically coupled to 5×5 SiPM arrays for a total 20×20 output channels. Test results showed excellent crystal identification for all 1024 LYSO crystals (each with 2×2×30 mm"3 size) with "2"2Na flood-source irradiation. The measured peak-to-valley ratio from typical crystal map profile is around 3:1 to 6.6:1, an average single crystal energy resolution of about 17.3%, and an average single crystal timing resolution of about 2 ns. Timing shift among different crystals, as reported in some other resistor-based multiplexing circuit designs, was not observed. In summary, we have designed and implemented a practical resistor-based multiplexing circuit that can be readily applied for reading out a large SiPM array with good detector performance.

  11. Design, development and evaluation of a resistor-based multiplexing circuit for a 20×20 SiPM array

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhonghai [College of Physical Science and Technology, Key Laboratory of Radiation Physics and Technology, Ministry of Education, Sichuan University, Chengdu (China); Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tx (United States); Sun, Xishan [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tx (United States); Lou, Kai [Department of Electrical and Computer Engineering, Rice University, Houston, Tx (United States); Meier, Joseph [Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Tx (United States); Zhou, Rong; Yang, Chaowen [College of Physical Science and Technology, Key Laboratory of Radiation Physics and Technology, Ministry of Education, Sichuan University, Chengdu (China); Zhu, Xiaorong [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Tx (United States); Shao, Yiping [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tx (United States)

    2016-04-21

    One technical challenge in developing a large-size scintillator detector with multiple Silicon Photomultiplier (SiPM) arrays is to read out a large number of detector output channels. To achieve this, different signal multiplexing circuits have been studied and applied with different performances and cost-effective tradeoffs. Resistor-based multiplexing circuits exhibit simplicity and signal integrity, but also present the disadvantage of timing shift among different channels. In this study, a resistor-based multiplexing circuit for a large-sized SiPM array readout was developed and evaluated by simulation and experimental studies. Similarly to a multiplexing circuit used for multi-anode PMT, grounding and branching resistors were connected to each SiPM output channel. The grounding resistor was used to simultaneously reduce the signal crosstalk among different channels and to improve timing performance. Both grounding and branching resistor values were optimized to maintain a balanced performance of the event energy, timing, and positioning. A multiplexing circuit was implemented on a compact PCB and applied for a flat-panel detector which consisted of a 32×32 LYSO scintillator crystals optically coupled to 5×5 SiPM arrays for a total 20×20 output channels. Test results showed excellent crystal identification for all 1024 LYSO crystals (each with 2×2×30 mm{sup 3} size) with {sup 22}Na flood-source irradiation. The measured peak-to-valley ratio from typical crystal map profile is around 3:1 to 6.6:1, an average single crystal energy resolution of about 17.3%, and an average single crystal timing resolution of about 2 ns. Timing shift among different crystals, as reported in some other resistor-based multiplexing circuit designs, was not observed. In summary, we have designed and implemented a practical resistor-based multiplexing circuit that can be readily applied for reading out a large SiPM array with good detector performance.

  12. Transition-edge sensor arrays for UV-optical-IR astrophysics

    International Nuclear Information System (INIS)

    Burney, J.; Bay, T.J.; Barral, J.; Brink, P.L.; Cabrera, B.; Castle, J.P.; Miller, A.J.; Nam, S.; Rosenberg, D.; Romani, R.W.; Tomada, A.

    2006-01-01

    Our research group has developed and characterized transition-edge sensor (TES) arrays for near IR-optical-near UV astrophysical observations. These detectors have a time-stamp accuracy of 0.3μs and an energy resolution of 0.16eV for 2.33eV photons at very high rates (30kHz). We have installed a 6x6 array of these TESs in an adiabatic demagnetization refrigerator equipped with windows for direct imaging. We discuss new instrumentation progress and current data in all aspects related to successful operation of this camera system, including: detector and array performance, position dependence and cross-talk, low-temperature and readout electronics, quantum and system efficiency, IR filtering, and focus and imaging

  13. Antibody array in a multiwell plate format for the sensitive and multiplexed detection of important plant pathogens.

    Science.gov (United States)

    Charlermroj, Ratthaphol; Himananto, Orawan; Seepiban, Channarong; Kumpoosiri, Mallika; Warin, Nuchnard; Gajanandana, Oraprapai; Elliott, Christopher T; Karoonuthaisiri, Nitsara

    2014-07-15

    The global seed market is considered to be an important industry with a total value of $10,543 million US dollars in 2012. Because plant pathogens such as bacteria and viruses cause a significant economic loss to both producers and exporters, the seed export industry urgently requires rapid, sensitive, and inexpensive testing for the pathogens to prevent disease spreading worldwide. This study developed an antibody array in a multiwell plate format to simultaneously detect four crucial plant pathogens, namely, a bacterial fruit blotch bacterium Acidovorax avenae subsp. citrulli (Aac), Chilli veinal mottle virus (ChiVMV, potyvirus), Watermelon silver mottle virus (WSMoV, tospovirus serogroup IV), and Melon yellow spot virus (MYSV, tospovirus). The capture antibodies specific to the pathogens were immobilized on each well at preassigned positions by an automatic microarrayer. The antibodies on the arrays specifically captured the corresponding pathogens present in the sample extracts. The presence of pathogens bound on the capture antibodies was subsequently detected by a cocktail of fluorescently conjugated secondary antibodies. The limits of detection of the developed antibody array for the detection of Aac, ChiVMV, WSMoV, and MYSV were 5 × 10(5) CFU/mL, 30 ng/mL, 1000 ng/mL, and 160 ng/mL, respectively, which were very similar to those of the conventional ELISA method. The antibody array in a multiwell plate format accurately detected plant pathogens in single and multiple detections. Moreover, this format enables easy handling of the assay at a higher speed of operation.

  14. U 1608-52: a Cornerstone in Our Understanding of the Khz Qpos

    Science.gov (United States)

    Mendez, Mariano

    We propose a series of ASM-triggered TOO observations of the atoll source 4U 1608-52 in outburst for a total of 450 ksec. These triggers are planned to maximize the probability of observing kHz QPOs and type- I X-ray bursts in this source. This is one of only 2 sources where the separation between the 2 simultaneous kHz QPOs varies significantly as a function of mass accretion rate. The detection of near-coherent oscillations during the bursts will provide a strong clue to the nature of the kHz QPOs in LMXBs, as it would make clear at which mass accretion level, if any, the kHz peak separation does approach the inferred spin rate.

  15. Development of multi-frequency array induction logging (MAIL) tool. 3; Multi shuhasu array gata induction kenso tool (MAIL) no kaihatsu (genchi shiken data no ichijigen kaiseki). 3

    Energy Technology Data Exchange (ETDEWEB)

    Sato, T; Osato, K; Takasugi, S [Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Uchida, T [New Energy and Industrial Technology Development Organization, Tokyo, (Japan)

    1996-05-01

    A field test was carried out in 1995 on a deep-seated geothermal investigation and reduction well WDR (in Kakkonda, Shizuku-ishi, Iwate Prefecture) by utilizing a multi-frequency array induction logging tool which is under development by NEDO. This paper reports results of analyzing the acquired data. With the WDR wells, an investigation has been conducted to a drilling depth of 330 m. Three frequencies in a range from 3 to 24 kHz provided relatively good data, but data with 42 kHz had poor quality that cannot be utilized for the analysis. Precise device calibration is difficult on data acquired from three array type vertical component magnetometers (the difficulty may be due to a signal line from a transmitter passing on the magnetometer side). Because of this difficulty, analysis using one-dimensional inversion program was performed by using ratio of the amplitude for each frequency and phase difference as input data. The analysis allowed to have derived a result that corresponds to the ground bed structure. 5 refs., 8 figs., 3 tabs.

  16. Four-to-one power combiner for 20 GHz phased array antenna using RADC MMIC phase shifters

    Science.gov (United States)

    1991-01-01

    The design and microwave simulation of two-to-one microstrip power combiners is described. The power combiners were designed for use in a four element phase array receive antenna subarray at 20 GHz. Four test circuits are described which were designed to enable testing of the power combiner and the four element phased array antenna. Test Circuit 1 enables measurement of the two-to-one power combiner. Test Circuit 2 enables measurement of the four-to-one power combiner. Test Circuit 3 enables measurement of a four element antenna array without phase shifting MMIC's in order to characterize the power combiner with the antenna patch-to-microstrip coaxial feedthroughs. Test circuit 4 is the four element phased array antenna including the RADC MMIC phase shifters and appropriate interconnects to provide bias voltages and control phase bits.

  17. 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids.

    Science.gov (United States)

    Hsiao, Amy Y; Tung, Yi-Chung; Qu, Xianggui; Patel, Lalit R; Pienta, Kenneth J; Takayama, Shuichi

    2012-05-01

    We previously reported the development of a simple, user-friendly, and versatile 384 hanging drop array plate for 3D spheroid culture and the importance of utilizing 3D cellular models in anti-cancer drug sensitivity testing. The 384 hanging drop array plate allows for high-throughput capabilities and offers significant improvements over existing 3D spheroid culture methods. To allow for practical 3D cell-based high-throughput screening and enable broader use of the plate, we characterize the robustness of the 384 hanging drop array plate in terms of assay performance and demonstrate the versatility of the plate. We find that the 384 hanging drop array plate performance is robust in fluorescence- and colorimetric-based assays through Z-factor calculations. Finally, we demonstrate different plate capabilities and applications, including: spheroid transfer and retrieval for Janus spheroid formation, sequential addition of cells for concentric layer patterning of different cell types, and culture of a wide variety of cell types. Copyright © 2011 Wiley Periodicals, Inc.

  18. Adaptive lesion formation using dual mode ultrasound array system

    Science.gov (United States)

    Liu, Dalong; Casper, Andrew; Haritonova, Alyona; Ebbini, Emad S.

    2017-03-01

    We present the results from an ultrasound-guided focused ultrasound platform designed to perform real-time monitoring and control of lesion formation. Real-time signal processing of echogenicity changes during lesion formation allows for identification of signature events indicative of tissue damage. The detection of these events triggers the cessation or the reduction of the exposure (intensity and/or time) to prevent overexposure. A dual mode ultrasound array (DMUA) is used for forming single- and multiple-focus patterns in a variety of tissues. The DMUA approach allows for inherent registration between the therapeutic and imaging coordinate systems providing instantaneous, spatially-accurate feedback on lesion formation dynamics. The beamformed RF data has been shown to have high sensitivity and specificity to tissue changes during lesion formation, including in vivo. In particular, the beamformed echo data from the DMUA is very sensitive to cavitation activity in response to HIFU in a variety of modes, e.g. boiling cavitation. This form of feedback is characterized by sudden increase in echogenicity that could occur within milliseconds of the application of HIFU (see http://youtu.be/No2wh-ceTLs for an example). The real-time beamforming and signal processing allowing the adaptive control of lesion formation is enabled by a high performance GPU platform (response time within 10 msec). We present results from a series of experiments in bovine cardiac tissue demonstrating the robustness and increased speed of volumetric lesion formation for a range of clinically-relevant exposures. Gross histology demonstrate clearly that adaptive lesion formation results in tissue damage consistent with the size of the focal spot and the raster scan in 3 dimensions. In contrast, uncontrolled volumetric lesions exhibit significant pre-focal buildup due to excessive exposure from multiple full-exposure HIFU shots. Stopping or reducing the HIFU exposure upon the detection of such an

  19. Moderate high power 1 to 20μs and kHz Ho:YAG thin disk laser pulses for laser lithotripsy

    Science.gov (United States)

    Renz, Günther

    2015-02-01

    An acousto-optically or self-oscillation pulsed thin disk Ho:YAG laser system at 2.1 μm with an average power in the 10 W range will be presented for laser lithotripsy. In the case of cw operation the thin disk Ho:YAG is either pumped with InP diode stacks or with a thulium fiber laser which leads to a laser output power of 20 W at an optical-to-optical efficiency of 30%. For the gain switched mode of operation a modulated Tm-fiber laser is used to produce self-oscillation pulses. A favored pulse lengths for uric acid stone ablation is known to be at a few μs pulse duration which can be delivered by the thin disk laser technology. In the state of the art laser lithotripter, stone material is typically ablated with 250 to 750 μs pulses at 5 to 10 Hz and with pulse energies up to a few Joule. The ablation mechanism is performed in this case by vaporization into stone dust and fragmentation. With the thin disk laser technology, 1 to 20 μs-laser pulses with a repetition rate of a few kHz and with pulse energies in the mJ-range are available. The ablation mechanism is in this case due to a local heating of the stone material with a decomposition of the crystalline structure into calcium carbonate powder which can be handled by the human body. As a joint process to this thermal effect, imploding water vapor bubbles between the fiber end and the stone material produce sporadic shock waves which help clear out the stone dust and biological material.

  20. The Advanced Gamma-ray Imaging System (AGIS): Topological Array Trigger

    Science.gov (United States)

    Smith, Andrew W.

    2010-03-01

    AGIS is a concept for the next-generation ground-based gamma-ray observatory. It will be an array of 36 imaging atmospheric Cherenkov telescopes (IACTs) sensitive in the energy range from 50 GeV to 200 TeV. The required improvements in sensitivity, angular resolution, and reliability of operation relative to the present generation instruments imposes demanding technological and cost requirements on the design of the telescopes and on the triggering and readout systems for AGIS. To maximize the capabilities of large arrays of IACTs with a low energy threshold, a wide field of view and a low background rate, a sophisticated array trigger is required. We outline the status of the development of a stereoscopic array trigger that calculates image parameters and correlates them across a subset of telescopes. Field Programmable Gate Arrays (FPGAs) implement the real-time pattern recognition to suppress cosmic rays and night-sky background events. A proof of principle system is being developed to run at camera trigger rates up to 10MHz and array-level rates up to 10kHz.

  1. The utility of sparse 2D fully electronically steerable focused ultrasound phased arrays for thermal surgery: a simulation study

    International Nuclear Information System (INIS)

    Ellens, Nicholas; Pulkkinen, Aki; Song Junho; Hynynen, Kullervo

    2011-01-01

    Sparse arrays are widely used in diagnostic ultrasound for their strong performance and relative technical simplicity. This simulation study assessed the efficacy of phased arrays of varied sparseness for thermal surgery, especially with regard to power consumption and near-field heating. It employs a linear ultrasound propagation model and a semi-analytical solution to the Pennes' bioheat transfer equation. The basic design had 4912 cylindrical transducers (500 kHz) arranged on a flat 12 cm disk (1.5 mm spacing). This array was compared to randomly-thinned sparse arrays with 75%, 50% and 25% populations. Temperature elevations of 60 and 70 deg. C were induced in sonication times of 5-20 s, at foci spanning depths of 50-150 mm and radii of 0-60 mm. The sparse arrays produced nearly indistinguishable focal patterns but, averaged across the foci, required 132%, 200% and 393% of the power of the full array, respectively, applied through fewer transducer elements. Comparable results were found at 1 MHz from equivalent arrays. Simulated lesions were formed (thermal dose ≥ 240 equivalent minutes at 43 deg. C (T 43 )) and 'transition' and 'unsafe' regions (both defined as 5 min 43 < 240 min) were identified, the former immediately surrounding the lesion and the latter anywhere else. At a depth of 100 mm, sparse arrays were found to produce comparable lesions to the full array at the focus, but 'unsafe', over-heated near-field regions after some ablated lesion volume: about 12 mL for the 25% array, around 100 mL for the 50% array, while the 75% and full arrays produced 150 mL lesions safely.

  2. Tubular fluoropolymer arrays with high piezoelectric response

    Science.gov (United States)

    Zhukov, Sergey; Eder-Goy, Dagmar; Biethan, Corinna; Fedosov, Sergey; Xu, Bai-Xiang; von Seggern, Heinz

    2018-01-01

    Polymers with electrically charged internal air cavities called ferroelectrets exhibit a pronounced piezoelectric effect and are regarded as soft functional materials suitable for sensor and actuator applications. In this work, a simple method for fabricating piezoelectret arrays with open-tubular channels is introduced. A set of individual fluoroethylenepropylene (FEP) tubes is compressed between two heated metal plates. The squeezed FEP tubes are melted together at +270 °C. The resulting structure is a uniform, multi-tubular, flat array that reveals a strong piezoelectric response after a poling step. The fabricated arrays have a high ratio between piezoelectrically active and non-active areas. The optimal charging voltage and stability of the piezoelectric coefficients with pressures and frequency were experimentally investigated for two specific array structures with wall thickness of 50 and 120 μm. The array fabricated from 50 μm thick FEP tubes reveals a stable and high piezoelectric coefficient of {d}33 = 120-160 pC N-1 with a flat frequency response between 0.1 Hz and 10 kHz for pressures between 1 and 100 kPa. An increase of wall thickness to 120 μm is accompanied by a more than twofold decrease in the piezoelectric coefficient as a result of a simultaneously higher effective array stiffness and lower remanent polarization. The obtained experimental results can be used to optimize the array design with regard to the electromechanical performance.

  3. Magnetic properties of Fe20 Ni80 antidots: Pore size and array disorder

    International Nuclear Information System (INIS)

    Palma, J.L.; Gallardo, C.; Spinu, L.; Vargas, J.M.; Dorneles, L.S.; Denardin, J.C.; Escrig, J.

    2013-01-01

    Magnetic properties of nanoscale Fe 20 Ni 80 antidot arrays with different hole sizes prepared on top of nanoporous alumina membranes have been studied by means of magnetometry and micromagnetic simulations. The results show a significant increase of the coercivity as well as a reduction of the remanence of the antidot arrays, as compared with their parent continuous film, which depends on the hole size introduced in the Fe 20 Ni 80 thin film. When the external field is applied parallel to the antidots, the reversal of magnetization is achieved by free-core vortex propagation, whereas when the external field is applied perpendicular to the antidots, the reversal occurs through a process other than the coherent rotation (a maze-like pattern). Besides, in-plane hysteresis loops varying the angle show that the degree of disorder in the sample breaks the expected hexagonal symmetry. - Highlights: • Magnetic properties are strongly influenced by the pore diameter of the samples. • Coercive fields for antidots are higher than the values for the continuous film. • Disorder breaks the hexagonal symmetry of the sample. • Each hole acts as a vortex nucleation point. • Antidots have unique properties that allow them to be used in applications

  4. Structural control of ultra-fine CoPt nanodot arrays via electrodeposition process

    Energy Technology Data Exchange (ETDEWEB)

    Wodarz, Siggi [Department of Applied Chemistry, Waseda University, Shinjuku, Tokyo 169-8555 (Japan); Hasegawa, Takashi; Ishio, Shunji [Department of Materials Science, Akita University, Akita City 010-8502 (Japan); Homma, Takayuki, E-mail: t.homma@waseda.jp [Department of Applied Chemistry, Waseda University, Shinjuku, Tokyo 169-8555 (Japan)

    2017-05-15

    CoPt nanodot arrays were fabricated by combining electrodeposition and electron beam lithography (EBL) for the use of bit-patterned media (BPM). To achieve precise control of deposition uniformity and coercivity of the CoPt nanodot arrays, their crystal structure and magnetic properties were controlled by controlling the diffusion state of metal ions from the initial deposition stage with the application of bath agitation. Following bath agitation, the composition gradient of the CoPt alloy with thickness was mitigated to have a near-ideal alloy composition of Co:Pt =80:20, which induces epitaxial-like growth from Ru substrate, thus resulting in the improvement of the crystal orientation of the hcp (002) structure from its initial deposition stages. Furthermore, the cross-sectional transmission electron microscope (TEM) analysis of the nanodots deposited with bath agitation showed CoPt growth along its c-axis oriented in the perpendicular direction, having uniform lattice fringes on the hcp (002) plane from the Ru underlayer interface, which is a significant factor to induce perpendicular magnetic anisotropy. Magnetic characterization of the CoPt nanodot arrays showed increase in the perpendicular coercivity and squareness of the hysteresis loops from 2.0 kOe and 0.64 (without agitation) to 4.0 kOe and 0.87 with bath agitation. Based on the detailed characterization of nanodot arrays, the precise crystal structure control of the nanodot arrays with ultra-high recording density by electrochemical process was successfully demonstrated. - Highlights: • Ultra-fine CoPt nanodot arrays were fabricated by electrodeposition. • Crystallinity of hcp (002) was improved with uniform composition formation. • Uniform formation of hcp lattices leads to an increase in the coercivity.

  5. Use of Microtremor Array Recordings for Mapping Subsurface Soil Structure, Singapore

    Science.gov (United States)

    Walling, M.

    2012-12-01

    Microtremor array recordings are carried out in Singapore, for different geology, to study the influence of each site in modeling the subsurface structure. The Spatial Autocorrelation (SPAC) method is utilized for the computation of the soil profiles. The array configuration of the recording consists of 7 seismometers, recording the vertical component of the ground motion, and the recording at each site is carried out for 30 minutes. The results from the analysis show that the soil structure modeled for the young alluvial of Kallang Formation (KF), in terms of shear wave velocity (Vs), gives a good correlation with borehole information, while for the older geological formation of Jurong Formation (JF) (sedimentary rock sequence) and Old Alluvial (OA) (dense alluvium formation), the correlation is not very clear due to the lack of impedance contrast. The older formation of Bukit Timah Granite (BTG) show contrasting results within the formation, with the northern BTG suggesting a low Vs upper layer of about 20m - 30m while the southern BTG reveals a dense formation. The discrepancy in the variation within BTG is confirmed from borehole data that reveals the northern BTG to have undergone intense weathering while the southern BTG have not undergone noticeable weathering. Few sites with bad recording quality could not resolve the soil structure. Microtremor array recording is good for mapping sites with soft soil formation and weathered rock formation but can be limited in the absence of subsurface velocity contrast and bad quality of microtremor records.; The correlation between the Vs30 estimated from SPAC method and borehole data for the four major geological formations of Singapore. The encircled sites are the sites with recording error.

  6. Evaluation of high frequency ghost cavitation emissions for two different seismic air-gun arrays using numerical modelling

    Science.gov (United States)

    Khodabandeloo, Babak; Landrø, Martin

    2017-04-01

    Sound is deployed by marine mammals for variety of vital purposes such as finding food, communication, echolocation, etc. On the other hand human activities generate underwater noise. One major type of acoustic source is marine seismic acquisition which is carried out to image layers beneath the seabed exploiting reflected acoustic and elastic waves. Air-gun arrays are the most common and efficient marine seismic sources. Field measurements using broad band hydrophones have revealed that acoustic energies emitted by air-gun arrays contains frequencies from a few Hz up to tens of kHz. Frequencies below 200 Hz benefit seismic imaging and the rest is normally considered as wasted energy. On the other hand, the high frequency range (above 200 Hz) overlaps with hearing curves of many marine mammals and especially toothed whales and may have an impact on their behavior. A phenomenon called ghost cavitation is recently recognized to be responsible for a major part of these high frequencies (> 5 kHz). Acoustic pressure waves of individual air guns reflected from sea surface can cause the hydrostatic pressure to drop towards zero close to the source array. In these regions there is a high probability for water vapor cavity growth and subsequent collapse. We have simulated ghost cavitation cloud using numerical modelling and the results are validated by comparing with field measurements. The model is used to compare the amount of high frequency noise due to ghost cavitation for two different air gun arrays. Both of the arrays have three subarrays but the array distance for the one with 2730 in3 air volume is 6 meters and for the slightly bigger array (3250 in3 in air volume) the subarrays are separated by 8 meters. Simulation results indicate that the second array, despite larger subarray distance, generates stronger ghost cavitation signal.

  7. A novel high electrode count spike recording array using an 81,920 pixel transimpedance amplifier-based imaging chip.

    Science.gov (United States)

    Johnson, Lee J; Cohen, Ethan; Ilg, Doug; Klein, Richard; Skeath, Perry; Scribner, Dean A

    2012-04-15

    Microelectrode recording arrays of 60-100 electrodes are commonly used to record neuronal biopotentials, and these have aided our understanding of brain function, development and pathology. However, higher density microelectrode recording arrays of larger area are needed to study neuronal function over broader brain regions such as in cerebral cortex or hippocampal slices. Here, we present a novel design of a high electrode count picocurrent imaging array (PIA), based on an 81,920 pixel Indigo ISC9809 readout integrated circuit camera chip. While originally developed for interfacing to infrared photodetector arrays, we have adapted the chip for neuron recording by bonding it to microwire glass resulting in an array with an inter-electrode pixel spacing of 30 μm. In a high density electrode array, the ability to selectively record neural regions at high speed and with good signal to noise ratio are both functionally important. A critical feature of our PIA is that each pixel contains a dedicated low noise transimpedance amplifier (∼0.32 pA rms) which allows recording high signal to noise ratio biocurrents comparable to single electrode voltage amplifier recordings. Using selective sampling of 256 pixel subarray regions, we recorded the extracellular biocurrents of rabbit retinal ganglion cell spikes at sampling rates up to 7.2 kHz. Full array local electroretinogram currents could also be recorded at frame rates up to 100 Hz. A PIA with a full complement of 4 readout circuits would span 1cm and could acquire simultaneous data from selected regions of 1024 electrodes at sampling rates up to 9.3 kHz. Published by Elsevier B.V.

  8. Simulating satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds

    OpenAIRE

    M. Füllekrug; C. Hanuise; M. Parrot

    2010-01-01

    Relativistic electron beams above thunderclouds emit 100 kHz radio waves which illuminate the Earth's atmosphere and near-Earth space. This contribution aims to clarify the physical processes which are relevant for the spatial spreading of the radio wave energy below and above the ionosphere and thereby enables simulating satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds. The simulation uses the DEMETER satellite which observes 100 kHz ...

  9. Lessons Learned in the Flight Qualification of the S-NPP and NOAA-20 Solar Array Mechanisms

    Science.gov (United States)

    Helfrich, Daniel; Sexton, Adam

    2018-01-01

    Deployable solar arrays are the energy source used on almost all Earth orbiting spacecraft and their release and deployment are mission-critical; fully testing them on the ground is a challenging endeavor. The 8 meter long deployable arrays flown on two sequential NASA weather satellites were each comprised of three rigid panels almost 2 meters wide. These large panels were deployed by hinges comprised of stacked constant force springs, eddy current dampers, and were restrained through launch by a set of four releasable hold-downs using shape memory alloy release devices. The ground qualification testing of such unwieldy deployable solar arrays, whose design was optimized for orbital operations, proved to be quite challenging and provides numerous lessons learned. A paperwork review and follow-up inspection after hardware storage determined that there were negative torque margins and missing lubricant, this paper will explain how these unexpected issues were overcome. The paper will also provide details on how the hinge subassemblies, the fully-assembled array, and mechanical ground support equipment were subsequently improved and qualified for a follow-on flight with considerably less difficulty. The solar arrays built by Ball Aerospace Corp. for the Suomi National Polar Partnership (S-NPP) satellite and the Joint Polar Satellite System (JPSS-1) satellite (now NOAA-20) were both successfully deployed on-obit and are performing well.

  10. Seafloor multibeam backscatter calibration experiment: comparing 45°-tilted 38-kHz split-beam echosounder and 30-kHz multibeam data

    Science.gov (United States)

    Ladroit, Yoann; Lamarche, Geoffroy; Pallentin, Arne

    2018-06-01

    Obtaining absolute seafloor backscatter measurements from hydrographic multibeam echosounders is yet to be achieved. We propose a low-cost experiment to calibrate the various acquisition modes of a 30-kHz Kongsberg EM 302 multibeam echosounder in a range of water depths. We use a 38-kHz Simrad EK60 calibrated fisheries split-beam echosounder mounted at 45° angle on the vessel's hull as a reference for the calibration. The processing to extract seafloor backscatter from the EK60 requires bottom detection, ray tracing and motion compensation to obtain acceptable geo-referenced backscatter measurements from this non-hydrographic system. Our experiment was run in Cook Strait, New Zealand, on well-known seafloor patches in shallow, mid, and deep-water depths. Despite acquisition issues due to weather, our results demonstrate the strong potential of such an approach to obtain system's absolute calibration which is required for quantitative use of backscatter strength data.

  11. Titanium K-Shell X-Ray Production from High Velocity Wire Arrays Implosions on the 20-MA Z Accelerator

    International Nuclear Information System (INIS)

    Apruzese, J.P.; Beg, F.N.; Clark, R.C.; Coverdale, C.A.; Davis, J.; Deeney, C.; Douglas, M.R.; Nash, T.J.; Ruiz-Comacho, J.; Spielman, R.B.; Struve, K.W.; Thornhill, J.W.; Whitney, K.G.

    1999-01-01

    The advent of the 20-MA Z accelerator [R.B. Spielman, C. Deeney, G.A. Chandler, et al., Phys. Plasmas 5, 2105, (1997)] has enabled implosions of large diameter, high-wire-number arrays of titanium to begin testing Z-pinch K-shell scaling theories. The 2-cm long titanium arrays, which were mounted on a 40-mm diameter, produced between 75±15 to 125±20 kJ of K-shell x-rays. Mass scans indicate that, as predicted, higher velocity implosions in the series produced higher x-ray yields. Spectroscopic analyses indicate that these high velocity implosions achieved peak electron temperatures from 2.7±0.1 to 3.2±0.2 keV and obtained a K-shell emission mass participation of up to 12%

  12. RPPAML/RIMS: a metadata format and an information management system for reverse phase protein arrays.

    Science.gov (United States)

    Stanislaus, Romesh; Carey, Mark; Deus, Helena F; Coombes, Kevin; Hennessy, Bryan T; Mills, Gordon B; Almeida, Jonas S

    2008-12-22

    Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technologies, substantial amounts of analytical data are generated. Over 1,000 samples may be printed on a single nitrocellulose slide. Up to 100 different proteins may be assessed using immunoperoxidase or immunoflorescence techniques in order to determine relative amounts of protein expression in the samples of interest. In this report an RPPA Information Management System (RIMS) is described and made available with open source software. In order to implement the proposed system, we propose a metadata format known as reverse phase protein array markup language (RPPAML). RPPAML would enable researchers to describe, document and disseminate RPPA data. The complexity of the data structure needed to describe the results and the graphic tools necessary to visualize them require a software deployment distributed between a client and a server application. This was achieved without sacrificing interoperability between individual deployments through the use of an open source semantic database, S3DB. This data service backbone is available to multiple client side applications that can also access other server side deployments. The RIMS platform was designed to interoperate with other data analysis and data visualization tools such as Cytoscape. The proposed RPPAML data format hopes to standardize RPPA data. Standardization of data would result in diverse client applications being able to operate on the same set of data. Additionally, having data in a standard format would enable data dissemination and data analysis.

  13. RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays

    Directory of Open Access Journals (Sweden)

    Hennessy Bryan T

    2008-12-01

    Full Text Available Abstract Background Reverse Phase Protein Arrays (RPPA are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technologies, substantial amounts of analytical data are generated. Over 1000 samples may be printed on a single nitrocellulose slide. Up to 100 different proteins may be assessed using immunoperoxidase or immunoflorescence techniques in order to determine relative amounts of protein expression in the samples of interest. Results In this report an RPPA Information Management System (RIMS is described and made available with open source software. In order to implement the proposed system, we propose a metadata format known as reverse phase protein array markup language (RPPAML. RPPAML would enable researchers to describe, document and disseminate RPPA data. The complexity of the data structure needed to describe the results and the graphic tools necessary to visualize them require a software deployment distributed between a client and a server application. This was achieved without sacrificing interoperability between individual deployments through the use of an open source semantic database, S3DB. This data service backbone is available to multiple client side applications that can also access other server side deployments. The RIMS platform was designed to interoperate with other data analysis and data visualization tools such as Cytoscape. Conclusion The proposed RPPAML data format hopes to standardize RPPA data. Standardization of data would result in diverse client applications being able to operate on the same set of data. Additionally, having data in a standard format would enable data dissemination and data analysis.

  14. 'Optical' soft x-ray arrays for fluctuation diagnostics in magnetic fusion energy experiments

    International Nuclear Information System (INIS)

    Delgado-Aparicio, L.F.; Stutman, D.; Tritz, K.; Finkenthal, M.; Kaita, R.; Roquemore, L.; Johnson, D.; Majeski, R.

    2004-01-01

    We are developing large pixel count, fast (≥100 kHz) and continuously sampling soft x-ray (SXR) array for the diagnosis of magnetohydrodynamics (MHD) and turbulent fluctuations in magnetic fusion energy plasmas. The arrays are based on efficient scintillators, high thoughput multiclad fiber optics, and multichannel light amplification and integration. Compared to conventional x-ray diode arrays, such systems can provide vastly increased spatial coverage, and access to difficult locations with small neutron noise and damage. An eight-channel array has been built using columnar CsI:Tl as an SXR converter and a multianode photomultiplier tube as photoamplifier. The overall system efficiency is measured using laboratory SXR sources, while the time response and signal-to-noise performance have been evaluated by recording MHD activity from the spherical tori (ST) Current Drive Experiment-Upgrade and National Spherical Torus Experiment, both at Princeton Plasma Physics Laboratory

  15. Mechanical frequency selectivity of an artificial basilar membrane using a beam array with narrow supports

    International Nuclear Information System (INIS)

    Kim, Sangwon; Jang, Jongmoon; Choi, Hongsoo; Song, Won Joon; Jang, Jeong Hun

    2013-01-01

    The study presented in this paper assessed the frequency selectivity of an artificial basilar membrane (ABM) constructed using a piezoelectric beam array with narrow supports. Three ABM samples were constructed. Each ABM contained 16 beams with various lengths in a one-dimensional array. To experimentally assess the frequency selectivity of the ABM, mechanical vibration induced either by an electrical or an acoustic stimulus was measured with a scanning laser-Doppler vibrometer. The electro-mechanical and acousto-mechanical transfer functions were defined for the same purpose. The tonotopy of each beam array was visualized by post-processing the experimental results. Finite element analyses were conducted to numerically compute the resonance frequencies, identify the associated vibrational modes, and evaluate the harmonic responses of the beams. The influence of the residual stresses existing in the beams was reflected in the geometric models by introducing three different levels of arc-shaped lateral deformations in the beams. The harmonic analyses revealed that each beam of the ABM samples presented independent band-pass characteristics. The experiments and simulations commonly showed a frequency selectivity of the fabricated ABMs in the range of 2–20 kHz. Therefore, the device is suitable for development of a totally implantable artificial cochlea, implementing a mechanical frequency analyzer. This work is part of research to develop a prototype of a totally implantable artificial cochlea. (paper)

  16. Applications of KHZ-CW Lidar in Ecological Entomology

    Science.gov (United States)

    Malmqvist, Elin; Brydegaard, Mikkel

    2016-06-01

    The benefits of kHz lidar in ecological entomology are explained. Results from kHz-measurements on insects, carried out with a CW-lidar system, employing the Scheimpflug principle to obtain range resolution, are presented. A method to extract insect events and analyze the large amount of lidar data is also described.

  17. Development of high-performance phased-array UT system 'DYNARAY' and its application examples

    International Nuclear Information System (INIS)

    Ehara, Eiji

    2011-01-01

    This article outlined the history leading to develop high-performance phased-array (PA) UT system called DYNARAY, with up to 256 phased-array active channels and maximum 4096 focal laws, lowering the inspection time. As examples it was applied to in-service inspection of reactor pressure vessel welded joints using module of PA-UT probe or eddy-current probe, inspection of seal welds of dry storage containers using scanner of PA-UT, crack detection of end ring of generators using PA-UT probe and UT inspection of cast austenitic stainless steel using 500 kHz probe. Advanced data acquisition and analysis functions for PA-UT system had been developed. (T. Tanaka)

  18. Perancangan Prototipe Transmitter Beacon Black Box Locator Acoustic 37.5 kHz Pingers

    OpenAIRE

    RUSTAMAJI RUSTAMAJI; KANIA SAWITRI; RUDI GUNAWAN

    2016-01-01

    ABSTRAK Pingers transmitter berfungsi untuk memancarkan sinyal atau getaran pulsa akustik pada black box. Frekuensi sinyal yang dipancarkan sebesar 37,5 kHz yang dimodulasikan oleh pulsa dengan durasi 10 ms setiap interval 1 second. Modulasi yang digunakan adalah modulasi on off keying. Dalam penelitian ini dibuat perancangan pingers transmitter yang tersusun atas rangkaian osilator, timer, inverter, switch dan rangkaian amplifier. Frekuensi 37,5 kHz tersebut dibangkitkan oleh rangkaian osi...

  19. Far infrared through millimeter backshort-under-grid arrays

    Science.gov (United States)

    Allen, Christine A.; Abrahams, John; Benford, Dominic J.; Chervenak, James A.; Chuss, David T.; Staguhn, Johannes G.; Miller, Timothy M.; Moseley, S. Harvey; Wollack, Edward J.

    2006-06-01

    We are developing a large-format, versatile, bolometer array for a wide range of infrared through millimeter astronomical applications. The array design consists of three key components - superconducting transition edge sensor bolometer arrays, quarter-wave reflective backshort grids, and Superconducting Quantum Interference Device (SQUID) multiplexer readouts. The detector array is a filled, square grid of bolometers with superconducting sensors. The backshort arrays are fabricated separately and are positioned in the etch cavities behind the detector grid. The grids have unique three-dimensional interlocking features micromachined into the walls for positioning and mechanical stability. The ultimate goal of the program is to produce large-format arrays with background-limited sensitivity, suitable for a wide range of wavelengths and applications. Large-format (kilopixel) arrays will be directly indium bump bonded to a SQUID multiplexer circuit. We have produced and tested 8×8 arrays of 1 mm detectors to demonstrate proof of concept. 8×16 arrays of 2 mm detectors are being produced for a new Goddard Space Flight Center instrument. We have also produced models of a kilopixel detector grid and dummy multiplexer chip for bump bonding development. We present detector design overview, several unique fabrication highlights, and assembly technologies.

  20. kHz femtosecond laser-plasma hard X-ray and fast ion source

    International Nuclear Information System (INIS)

    Thoss, A.; Korn, G.; Stiel, H.; Voigt, U.; Elsaesser, T.; Richardson, M.C.; Siders, C.W.; Faubel, M.

    2002-01-01

    We describe the first demonstration of a new stable, kHz femtosecond laser-plasma source of hard x-ray continuum and K α emission using a thin liquid metallic jet target. kHz femtosecond x-ray sources will find many applications in time-resolved x-ray diffraction and microscopy studies. As high intensity lasers become more compact and operate at increasingly high repetition-rates, they require a target configuration that is both repeatable from shot-to-shot and is debris-free. We have solved this requirement with the use of a fine (10-30 μm diameter) liquid metal jet target that provides a pristine, unperturbed filament surface at rates >100 kHz. A number of liquid metal targets are considered. We will show hard x-ray spectra recorded from liquid Ga targets that show the generation of the 9.3 keV and 10.3 keV, K α and K β lines superimposed on a multi-keV Bremsstrahlung continuum. This source was generated by a 50fs duration, 1 kHz, 2W, high intensity Ti:Sapphire laser. We will discuss the extension of this source to higher powers and higher repetition rates, providing harder x-ray emission, with the incorporation of pulse-shaping and other techniques to enhance the x-ray conversion efficiency. Using the same liquid target technology, we have also demonstrated the generation of forward-going sub-MeV protons from a 10 μm liquid water target at 1 kHz repetition rates. kHz sources of high energy ions will find many applications in time-resolved particle interaction studies, as well as lead to the efficient generation of short-lived isotopes for use in nuclear medicine and other applications. The protons were detected with CR-39 track detectors both in the forward and backward directions up to energies of ∼500 keV. As the intensity of compact high repetition-rate lasers sources increase, we can expect improvements in the energy, conversion efficiency and directionality to occur. The impact of these developments on a number of fields will be discussed. As compact

  1. A High Power InGaN-Based Blue-Violet Laser Diode Array with a Broad-Area Stripe

    International Nuclear Information System (INIS)

    Chen Ping; Zhao De-Gang; Feng Mei-Xin; Jiang De-Sheng; Liu Zong-Shun; Yang Hui; Zhang Li-Qun; Li De-Yao; Liu Jian-Ping; Wang Hui; Zhu Jian-Jun; Zhang Shu-Ming; Zhang Bao-Shun

    2013-01-01

    An array of high power InGaN/GaN multi-quantum-well laser diodes with a broad waveguide is fabricated. The laser diode structure is grown on a GaN substrate by metal-organic chemical vapor deposition. The laser diode array consists of five emitter stripes which share common electrodes on one laser chip. The electrical and optical characteristics of the laser diode array are investigated under the pulse current injection with 10kHz frequency and 100 ns pulse width. The laser diode array emits at the wavelength of 409 nm, which is located in the blue-violet region, and the threshold current is 2.9 A. The maximum output light peak power is measured to be 7.5 W at the wavelength of 411.8 nm under the current of 25 A

  2. Residential photovoltaic module and array requirement study. Low-Cost Solar Array Project engineering area. Final report appendices

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-01

    This volume contains the appendices to a study to identify design requirements for photovoltaic modules and arrays used in residential applications. Appendices include: (1) codes, standards, and manuals of accepted practice-definition and importance; (2) regional code variations-impact; (3) model and city codes-review; (4) National Electric Code (NEC)-review; (5) types of standards-definition and importance; (6) federal standards-review; (7) standards review method; (8) manuals of accepted practice; (9) codes and referenced standards-summary; (10) public safety testing laboratories; (11) insurance review; (12) studies approach; (13) mounting configurations; (14) module/panel size and shape cost analysis; (15) grounding, wiring, terminal and voltage studies; (16) array installation cost summary; (17) photovoltaic shingle/module comparison; (18) retrofit application; (19) residential photovoltaic module performance criteria; (20) critique of JPL's solar cell module design and test specifications for residential applications; and (21) CSI format specification. (WHK)

  3. Formation of nano-sized pinholes array in thin Ni film on MgO(100) substrate

    Energy Technology Data Exchange (ETDEWEB)

    Lin Chuan; Naramoto, Hiroshi; Xu Yonghua; Kitazawa, Sin-iti; Narumi, Kazumasa; Sakai, Seiji

    2003-10-22

    We have grown thin Ni films with various thicknesses on polished MgO(100) single crystal substrates in an e-gun evaporation system. The morphology of the as-deposited films was characterized with atomic force microscopy. Pinholes with average diameter of 5-10 nm are found in the film with thickness from 1 to 15 nm, and pinholes array was observed in the film 10 nm thick. The origin of such structure formation is discussed in terms of the elastic strain energy.

  4. Magnetic properties of Fe{sub 20} Ni{sub 80} antidots: Pore size and array disorder

    Energy Technology Data Exchange (ETDEWEB)

    Palma, J.L., E-mail: juan.palma.s@usach.cl [Departamento de Física, Universidad de Santiago de Chile (USACH), Avda. Ecuador 3493, 917-0124 Santiago (Chile); Gallardo, C. [Departamento de Física, Universidad de Santiago de Chile (USACH), Avda. Ecuador 3493, 917-0124 Santiago (Chile); Spinu, L.; Vargas, J.M. [Advanced Material Research Institute (AMRI) and Department of Physics, University of New Orleans, New Orleans, LA 70148 (United States); Dorneles, L.S. [Departamento de Fisica, Universidade Federal de Santa Maria UFSM, Av. Roraima 1000, Camobi, Santa Maria, RS 97105-900 (Brazil); Denardin, J.C.; Escrig, J. [Departamento de Física, Universidad de Santiago de Chile (USACH), Avda. Ecuador 3493, 917-0124 Santiago (Chile); Center for the Development of Nanoscience and Nanotechnology (CEDENNA), Avda. Ecuador 3493, 917-0124 Santiago (Chile)

    2013-10-15

    Magnetic properties of nanoscale Fe{sub 20}Ni{sub 80} antidot arrays with different hole sizes prepared on top of nanoporous alumina membranes have been studied by means of magnetometry and micromagnetic simulations. The results show a significant increase of the coercivity as well as a reduction of the remanence of the antidot arrays, as compared with their parent continuous film, which depends on the hole size introduced in the Fe{sub 20}Ni{sub 80} thin film. When the external field is applied parallel to the antidots, the reversal of magnetization is achieved by free-core vortex propagation, whereas when the external field is applied perpendicular to the antidots, the reversal occurs through a process other than the coherent rotation (a maze-like pattern). Besides, in-plane hysteresis loops varying the angle show that the degree of disorder in the sample breaks the expected hexagonal symmetry. - Highlights: • Magnetic properties are strongly influenced by the pore diameter of the samples. • Coercive fields for antidots are higher than the values for the continuous film. • Disorder breaks the hexagonal symmetry of the sample. • Each hole acts as a vortex nucleation point. • Antidots have unique properties that allow them to be used in applications.

  5. Characteristics of a four element gyromagnetic nonlinear transmission line array high power microwave source

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, J. M., E-mail: jared.johnson@ttu.edu; Reale, D. V.; Garcia, R. S.; Cravey, W. H.; Neuber, A. A.; Dickens, J. C.; Mankowski, J. J. [Center for Pulsed Power and Power Electronics Department of Electrical and Computer Engineering, Texas Tech University, Lubbock, Texas 79409 (United States); Krile, J. T. [Department of Electromagnetics and Sensor Systems, Naval Surface Warfare Center - Dahlgren Division, Dahlgren, Virginia 22448 (United States)

    2016-05-15

    In this paper, a solid-state four element array gyromagnetic nonlinear transmission line high power microwave system is presented as well as a detailed description of its subsystems and general output capabilities. This frequency agile S-band source is easily adjusted from 2-4 GHz by way of a DC driven biasing magnetic field and is capable of generating electric fields of 7.8 kV/m at 10 m correlating to 4.2 MW of RF power with pulse repetition frequencies up to 1 kHz. Beam steering of the array at angles of ±16.7° is also demonstrated, and the associated general radiation pattern is detailed.

  6. Perancangan Prototipe Receiver Beacon Black Box Locator Acoustic 37,5 kHz Pingers

    OpenAIRE

    RUSTAMAJI RUSTAMAJI; PAULINE RAHMIATI; SARAH PERMATASARI

    2016-01-01

    ABSTRAK Ketika suatu pesawat terbang mengalami kecelakaan terjatuh ke dalam air, maka lokasi keberadaannya dapat dideteksi oleh alat yang disebut receiver beacon black box locator acoustic (pingers receiver). Pingers receiver berfungsi untuk menerima sinyal dengan frekuensi 37,5 kHz ± 1 kHz dari pingers transmitter atau Underwater Locator Beacon (ULB) yang berada pada black box pesawat. Dalam penelitian ini dibuat perancangan pingers receiver yang tersusun dari rangkaian Band Pass Filter (BPF...

  7. Pattern formation in arrays of chemical oscillators

    Indian Academy of Sciences (India)

    Chemical oscillators; phase flip; oscillation death. PACS No. 05.45 .... array oscillate (with varying amplitudes and frequencies), while the others experience oscillation death .... Barring the boundary cells, one observes near phase flip and near ...

  8. Tailoring the High-Q LC Filter Arrays for Readout of Kilo-Pixel TES Arrays in the SPICA-SAFARI Instrument

    Science.gov (United States)

    Bruijn, M. P.; Gottardi, L.; den Hartog, R. H.; van der Kuur, J.; van der Linden, A. J.; Jackson, B. D.

    2014-08-01

    Following earlier presentations of arrays of high quality factor (Q 10.000) superconducting resonators in the MHz regime, we report on improvement of the packing density of resonance frequencies to 160 in the 1-3 MHz band. Spread in the spacing of resonances is found to be limited to 1 kHz (1 with the present fabrication procedure. The present packing density of frequencies and chip area approaches the requirements for the SAFARI instrument on the SPICA mission (in preparation). The a-Si:H dielectric layer in the planar S-I-S capacitors shows a presently unexplained apparent negative effective series resistance, depending on operating temperature and applied testing voltage.

  9. 41 CFR 300-2.20 - What is the purpose of the question & answer format?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is the purpose of the question & answer format? 300-2.20 Section 300-2.20 Public Contracts and Property Management Federal Travel Regulation System GENERAL INTRODUCTION 2-HOW TO USE THE FTR Question & Answer Format § 300...

  10. MIRAGE WF infrared scene projector system, with 1536 x 768 wide format resistive array, performance data

    Science.gov (United States)

    Sparkman, Kevin; Laveigne, Joe; Oleson, Jim; Franks, Greg; McHugh, Steve; Lannon, John; Woode, Brian; Greer, Derek; Bui, Nicole

    2009-05-01

    MIRAGE WF is the latest high definition version of the MIRAGE infrared scene projector product line from Santa Barbara Infrared Inc. (SBIR). MIRAGE WF is being developed under the Wide Format Resistive Array (WFRA) program. The WFRA development is one of several efforts within the Infrared Sensor Simulator - Preplanned Product Improvement (IRSS P3I) umbrella funded by the Central Test and Evaluation Investment Program (CTEIP) and led by the US Navy at Patuxent River, MD. Three MIRAGE WF infrared scene projection systems are being delivered as part of the WFRA program. The main differences between the MIRAGE XL (1024x1024) and MIRAGE WF are a 1536x768 emitter array and 100Hz true raster capability. The key emitter requirements that have been measured and will be discussed include: Operability, Maximum Apparent Temperature, Rise Time and Array Uniformity. Key System specifications are: 1536x768 pixels, maximum apparent temperature of 600K, maximum frame rate of 100Hz, raster and snap shot updating, radiance rise and fall time less than 5 ms and windowed mode (1024x768) operation at up to 200 Hz.

  11. ZnO nano-array-based EGFET biosensor for glucose detection

    Science.gov (United States)

    Qi, Junjie; Zhang, Huihui; Ji, Zhaoxia; Xu, Minxuan; Zhang, Yue

    2015-06-01

    Electrochemical biosensors are normally based on enzymatic catalysis of a reaction that produces or consumes electrons and the sensing membranes dominate the performance. In this work, ZnO nano-array-based EGFETs were fabricated for pH and glucose detection. The ZnO nano-arrays prepared via low-temperature hydrothermal method were well-aligned, with an average length of 2 μm and diameter of 100-150 nm, and have a typical hexagonal wurtzite structure. The sensor performed with a sensitivity of 45 mV/pH and response time of about 6-7 s from pH = 4-12. UV irradiation can improve the Vref response as a result of the formation of a depletion region at the surface of ZnO nanomaterials. Due to its high specific surface area, the ZnO nano-array EGFET sensor showed a sensitivity of -0.395 mV/μM to the glucose detection in a concentration range between 20 and 100 μM. These EGFET glucose biosensors demonstrate a low detectable concentration (20 μM) with good linearity, therefore may be used to detect glucose in saliva and tears at much lower concentrations than that in blood.

  12. A dumbbell-shaped hybrid magnetometer operating in DC-10 kHz

    Science.gov (United States)

    Shi, Hongyu; Wang, Yanzhang; Chen, Siyu; Lin, Jun

    2017-12-01

    This study is motivated by the need to design a hybrid magnetometer operating in a wide-frequency band from DC to 10 kHz. To achieve this objective, a residence times difference fluxgate magnetometer (RTDFM) and an induction magnetometer (IM) have been integrated into a compact form. The hybrid magnetometer has a dumbbell-shaped structure in which the RTDFM transducer is partially inserted into the tube cores of the IM. Thus, the sensitivity of the RTDFM is significantly improved due to the flux amplification. The optimal structure, which has maximum sensitivity enhancement, was obtained through FEM analysis. To validate the theoretical analysis, the optimal hybrid magnetometer was manufactured, and its performance was evaluated. The device has a sensitivity of 45 mV/nT at 1 kHz in IM mode and 0.38 μs/nT in RTDFM mode, which is approximately 3.45 times as large as that of the single RTDFM structure. Furthermore, to obtain a lower noise performance in the entire frequency band, two operation modes switch at the cross frequency (0.16 Hz) of their noise levels. The noise level is 30 pT/√Hz in RTDFM mode and 0.07 pT/√Hz at 1 kHz in IM mode.

  13. 20 CFR 626.2 - Format of the Job Training Partnership Act regulations.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Format of the Job Training Partnership Act regulations. 626.2 Section 626.2 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INTRODUCTION TO THE REGULATIONS UNDER THE JOB TRAINING PARTNERSHIP ACT § 626.2 Format of the Job...

  14. Ultraino: An Open Phased-Array System for Narrowband Airborne Ultrasound Transmission.

    Science.gov (United States)

    Marzo, Asier; Corkett, Tom; Drinkwater, Bruce W

    2018-01-01

    Modern ultrasonic phased-array controllers are electronic systems capable of delaying the transmitted or received signals of multiple transducers. Configurable transmit-receive array systems, capable of electronic steering and shaping of the beam in near real-time, are available commercially, for example, for medical imaging. However, emerging applications, such as ultrasonic haptics, parametric audio, or ultrasonic levitation, require only a small subset of the capabilities provided by the existing controllers. To meet this need, we present Ultraino, a modular, inexpensive, and open platform that provides hardware, software, and example applications specifically aimed at controlling the transmission of narrowband airborne ultrasound. Our system is composed of software, driver boards, and arrays that enable users to quickly and efficiently perform research in various emerging applications. The software can be used to define array geometries, simulate the acoustic field in real time, and control the connected driver boards. The driver board design is based on an Arduino Mega and can control 64 channels with a square wave of up to 17 Vpp and /5 phase resolution. Multiple boards can be chained together to increase the number of channels. The 40-kHz arrays with flat and spherical geometries are demonstrated for parametric audio generation, acoustic levitation, and haptic feedback.

  15. Testing social acoustic memory in rats: effects of stimulus configuration and long-term memory on the induction of social approach behavior by appetitive 50-kHz ultrasonic vocalizations.

    Science.gov (United States)

    Wöhr, Markus; Schwarting, Rainer K W

    2012-09-01

    Rats emit distinct types of ultrasonic vocalizations (USVs), which serve as situation-dependent affective signals. In appetitive situations, such as rough-and-tumble-play, high-frequency 50-kHz USVs occur, whereas low-frequency 22-kHz USVs can be observed in aversive situations, such as social defeat. USVs serve distinct communicative functions and induce call-specific behavioral responses in the receiver. While aversive 22-kHz USVs serve as alarm calls and induce behavioral inhibition, appetitive 50-kHz USVs have a pro-social communicative function and elicit social approach behavior, supporting the notion that they serve as social contact calls to (re)establish or maintain contact among conspecifics. The aim of the present study was to use the rat's ability to communicate in the ultrasonic range via high-frequency 50-kHz USVs in order to develop a test for social acoustic memory in rats with relevance for human verbal memory. Verbal learning and memory is among the seven cognitive domains identified as commonly deficient in human schizophrenia patients, but particularly difficult to model. We therefore tested whether the induction of social approach behavior by playback of appetitive 50-kHz USVs is dependent on (1) acoustic stimulus configuration and (2) social long-term memory, and whether (3) social long-term memory effects can be blocked by the administration of scopolamine, a muscarinic acetylcholine antagonist producing amnesia. Results show that social approach behavior in response to playback of natural 50-kHz USVs depends on acoustic stimulus configuration and occurs only when sound energy is concentrated to a critical frequency band in the ultrasonic range. Social approach behavior was detected during the first exposure to playback of 50-kHz USVs, whereas no such response was observed during the second exposure 1week later, indicating a stable memory trace. In contrast, when memory formation was blocked by i.p. administration of scopolamine (0.5mg/kg or

  16. A method for the formation of Pt metal nanoparticle arrays using nanosecond pulsed laser dewetting

    Energy Technology Data Exchange (ETDEWEB)

    Owusu-Ansah, Ebenezer; Horwood, Corie A.; Birss, Viola I.; Shi, Yujun J., E-mail: shiy@ucalgary.ca [Department of Chemistry, University of Calgary, Calgary, Alberta T2N 1N4 (Canada); El-Sayed, Hany A. [Institute for Technical Electrochemistry, Technische Universität München, D-85748 Garching (Germany)

    2015-05-18

    Nanosecond pulsed laser dewetting of Pt thin films, deposited on a dimpled Ta (DT) surface, has been studied here in order to form ordered Pt nanoparticle (NP) arrays. The DT substrate was fabricated via a simple electrochemical anodization process in a highly concentrated H{sub 2}SO{sub 4} and HF solution. Pt thin films (3–5 nm) were sputter coated on DT and then dewetted under vacuum to generate NPs using a 355 nm laser radiation (6–9 ns, 10 Hz). The threshold laser fluence to fully dewet a 3.5 nm thick Pt film was determined to be 300 mJ/cm{sup 2}. Our experiments have shown that shorter irradiation times (≤60 s) produce smaller nanoparticles with more uniform sizes, while longer times (>60 s) give large nanoparticles with wider size distributions. The optimum laser irradiation time of 1 s (10 pulses) has led to the formation of highly ordered Pt nanoparticle arrays with an average nanoparticle size of 26 ± 3 nm with no substrate deformation. At the optimum condition of 1 s and 500 mJ/cm{sup 2}, as many as 85% of the dewetted NPs were found neatly in the well-defined dimples. This work has demonstrated that pulsed laser dewetting of Pt thin films on a pre-patterned dimpled substrate is an efficient and powerful technique to produce highly ordered Pt nanoparticle arrays. This method can thus be used to produce arrays of other high-melting-point metal nanoparticles for a range of applications, including electrocatalysis, functionalized nanomaterials, and analytical purposes.

  17. Performance assessments of vertically aligned carbon nanotubes multi-electrode arrays using Cath.a-differentiated (CAD) cells

    Science.gov (United States)

    Jeong, Du Won; Jung, Jongjin; Kim, Gook Hwa; Yang, Cheol-Soo; Kim, Ju Jin; Jung, Sang Don; Lee, Jeong-O.

    2015-08-01

    In this work, Cath.a-differentiated (CAD) cells were used in place of primary neuronal cells to assess the performance of vertically aligned carbon nanotubes (VACNTs) multi-electrode arrays (MEA). To fabricate high-performance MEA, VACNTs were directly grown on graphene/Pt electrodes via plasma enhanced chemical deposition technique. Here, graphene served as an intermediate layer lowering contact resistance between VACNTs and Pt electrode. In order to lower the electrode impedance and to enhance the cell adhesion, VACNTs-MEAs were treated with UV-ozone for 20 min. Impedance of VACNTs electrode at 1 kHz frequency exhibits a reasonable value (110 kΩ) for extracellular signal recording, and the signal to noise ratio the is good enough to measure low signal amplitude (15.7). Spontaneous firing events from CAD cells were successfully measured with VACNTs MEAs that were also found to be surprisingly robust toward the biological interactions.

  18. Performance assessments of vertically aligned carbon nanotubes multi-electrode arrays using Cath.a-differentiated (CAD) cells

    International Nuclear Information System (INIS)

    Jeong, Du Won; Jin Kim, Ju; Jung, Jongjin; Yang, Cheol-Soo; Lee, Jeong-O; Hwa Kim, Gook; Don Jung, Sang

    2015-01-01

    In this work, Cath.a-differentiated (CAD) cells were used in place of primary neuronal cells to assess the performance of vertically aligned carbon nanotubes (VACNTs) multi-electrode arrays (MEA). To fabricate high-performance MEA, VACNTs were directly grown on graphene/Pt electrodes via plasma enhanced chemical deposition technique. Here, graphene served as an intermediate layer lowering contact resistance between VACNTs and Pt electrode. In order to lower the electrode impedance and to enhance the cell adhesion, VACNTs-MEAs were treated with UV–ozone for 20 min. Impedance of VACNTs electrode at 1 kHz frequency exhibits a reasonable value (110 kΩ) for extracellular signal recording, and the signal to noise ratio the is good enough to measure low signal amplitude (15.7). Spontaneous firing events from CAD cells were successfully measured with VACNTs MEAs that were also found to be surprisingly robust toward the biological interactions. (paper)

  19. Readout of a 176 pixel FDM system for SAFARI TES arrays

    Science.gov (United States)

    Hijmering, R. A.; den Hartog, R.; Ridder, M.; van der Linden, A. J.; van der Kuur, J.; Gao, J. R.; Jackson, B.

    2016-07-01

    In this paper we present the results of our 176-pixel prototype of the FDM readout system for SAFARI, a TES-based focal-plane instrument for the far-IR SPICA mission. We have implemented the knowledge obtained from the detailed study on electrical crosstalk reported previously. The effect of carrier leakage is reduced by a factor two, mutual impedance is reduced to below 1 nH and mutual inductance is removed. The pixels are connected in stages, one quarter of the array half of the array and the full array, to resolve intermediate technical issues. A semi-automated procedure was incorporated to find all optimal settings for all pixels. And as a final step the complete array has been connected and 132 pixels have been read out simultaneously within the frequency range of 1-3.8MHz with an average frequency separation of 16kHz. The noise was found to be detector limited and was not affected by reading out all pixels in a FDM mode. With this result the concept of using FDM for multiplexed bolometer read out for the SAFARI instrument has been demonstrated.

  20. SPECTRAL-TIMING ANALYSIS OF THE LOWER kHz QPO IN THE LOW-MASS X-RAY BINARY AQUILA X-1

    Energy Technology Data Exchange (ETDEWEB)

    Troyer, Jon S.; Cackett, Edward M., E-mail: jon.troyer@wayne.edu [Department of Physics and Astronomy, Wayne State University, 666 W. Hancock St, Detroit, MI 48201 (United States)

    2017-01-10

    Spectral-timing products of kilohertz quasi-periodic oscillations (kHz QPOs) in low-mass X-ray binary (LMXB) systems, including energy- and frequency-dependent lags, have been analyzed previously in 4U 1608-52, 4U 1636-53, and 4U 1728-34. Here, we study the spectral-timing properties of the lower kHz QPO of the neutron star LMXB Aquila X-1 for the first time. We compute broadband energy lags as well as energy-dependent lags and the covariance spectrum using data from the Rossi X-ray Timing Explorer . We find characteristics similar to those of previously studied systems, including soft lags of ∼30 μ s between the 3.0–8.0 keV and 8.0–20.0 keV energy bands at the average QPO frequency. We also find lags that show a nearly monotonic trend with energy, with the highest-energy photons arriving first. The covariance spectrum of the lower kHz QPO is well fit by a thermal Comptonization model, though we find a seed photon temperature higher than that of the mean spectrum, which was also seen in Peille et al. and indicates the possibility of a composite boundary layer emitting region. Lastly, we see in one set of observations an Fe K component in the covariance spectrum at 2.4- σ confidence, which may raise questions about the role of reverberation in the production of lags.

  1. Use of a Microphone Phased Array to Determine Noise Sources in a Rocket Plume

    Science.gov (United States)

    Panda, J.; Mosher, R.

    2010-01-01

    A 70-element microphone phased array was used to identify noise sources in the plume of a solid rocket motor. An environment chamber was built and other precautions were taken to protect the sensitive condenser microphones from rain, thunderstorms and other environmental elements during prolonged stay in the outdoor test stand. A camera mounted at the center of the array was used to photograph the plume. In the first phase of the study the array was placed in an anechoic chamber for calibration, and validation of the indigenous Matlab(R) based beamform software. It was found that the "advanced" beamform methods, such as CLEAN-SC was partially successful in identifying speaker sources placed closer than the Rayleigh criteria. To participate in the field test all equipments were shipped to NASA Marshal Space Flight Center, where the elements of the array hardware were rebuilt around the test stand. The sensitive amplifiers and the data acquisition hardware were placed in a safe basement, and 100m long cables were used to connect the microphones, Kulites and the camera. The array chamber and the microphones were found to withstand the environmental elements as well as the shaking from the rocket plume generated noise. The beamform map was superimposed on a photo of the rocket plume to readily identify the source distribution. It was found that the plume made an exceptionally long, >30 diameter, noise source over a large frequency range. The shock pattern created spatial modulation of the noise source. Interestingly, the concrete pad of the horizontal test stand was found to be a good acoustic reflector: the beamform map showed two distinct source distributions- the plume and its reflection on the pad. The array was found to be most effective in the frequency range of 2kHz to 10kHz. As expected, the classical beamform method excessively smeared the noise sources at lower frequencies and produced excessive side-lobes at higher frequencies. The "advanced" beamform

  2. Phased Array Focusing for Acoustic Wireless Power Transfer.

    Science.gov (United States)

    Tseng, Victor Farm-Guoo; Bedair, Sarah S; Lazarus, Nathan

    2018-01-01

    Wireless power transfer (WPT) through acoustic waves can achieve higher efficiencies than inductive coupling when the distance is above several times the transducer size. This paper demonstrates the use of ultrasonic phased arrays to focus power to receivers at arbitrary locations to increase the power transfer efficiency. Using a phased array consisting of 37 elements at a distance nearly 5 times the receiver transducer diameter, a factor of 2.6 increase in efficiency was achieved when compared to a case equivalent to a single large transducer with the same peak efficiency distance. The array has a total diameter of 7 cm, and transmits through air at 40 kHz to a 1.1-cm diameter receiver, achieving a peak overall efficiency of 4% at a distance of 5 cm. By adjusting the focal distance, the efficiency can also be maintained relatively constant at distances up to 9 cm. Numerical models were developed and shown to closely match the experimental energy transfer behavior; modeling results indicate that the efficiency can be further doubled by increasing the number of elements. For comparison, an inductive WPT system was also built with the diameters of the transmitting and receiving coils equivalent to the dimensions of the transmitting ultrasonic phased array and receiver transducer, and the acoustic WPT system achieved higher efficiencies than the inductive WPT system when the transmit-to-receive distance is above 5 cm. In addition, beam angle steering was demonstrated by using a simplified seven-element 1-D array, achieving power transfer less dependent on receiver placement.

  3. Micromachined microphone array on a chip for turbulent boundary layer measurements

    Science.gov (United States)

    Krause, Joshua Steven

    A surface micromachined microphone array on a single chip has been successfully designed, fabricated, characterized, and tested for aeroacoustic purposes. The microphone was designed to have venting through the diaphragm, 64 elements (8x8) on the chip, and used a capacitive transduction scheme. The microphone was fabricated using the MEMSCAP PolyMUMPs process (a foundry polysilicon surface micromachining process) along with facilities at Tufts Micro and Nano Fabrication Facility (TMNF) where a Parylene-C passivation layer deposition and release of the microstructures were performed. The devices are packaged with low profile interconnects, presenting a maximum of 100 mum of surface topology. The design of an individual microphone was completed through the use of a lumped element model (LEM) to determine the theoretical performance of the microphone. Off-chip electronics were created to allow the microphone array outputs to be redirected to one of two channels, allowing dynamic reconfiguration of the effective transducer shape in software and provide 80 dB off isolation. The characterization was completed through the use of laser Doppler vibrometry (LDV), acoustic plane wave tube and free-field calibration, and electrical noise floor testing in a Faraday cage. Measured microphone sensitivity is 0.15 mV/Pa for an individual microphone and 8.7 mV/Pa for the entire array, in close agreement with model predictions. The microphones and electronics operate over the 200--40 000 Hz band. The dynamic range extends from 60 dB SPL in a 1 Hz band to greater than 150 dB SPL. Element variability was +/-0.05 mV/Pa in sensitivity with an array yield of 95%. Wind tunnel testing at flow rates of up to 205.8 m/s indicates that the devices continue to operate in flow without damage, and can be successfully reconfigured on the fly. Care has been taken to systematically remove contaminating signals (acoustic, vibration, and noise floor) from the wind tunnel data to determine actual

  4. Description of a 20 Kilohertz power distribution system

    Science.gov (United States)

    Hansen, I. G.

    1986-01-01

    A single phase, 440 VRMS, 20 kHz power distribution system with a regulated sinusoidal wave form is discussed. A single phase power system minimizes the wiring, sensing, and control complexities required in a multi-sourced redundantly distributed power system. The single phase addresses only the distribution link; mulitphase lower frequency inputs and outputs accommodation techniques are described. While the 440 V operating potential was initially selected for aircraft operating below 50,000 ft, this potential also appears suitable for space power systems. This voltage choice recognizes a reasonable upper limit for semiconductor ratings, yet will direct synthesis of 220 V, 3 power. A 20 kHz operating frequency was selected to be above the range of audibility, minimize the weight of reactive components, yet allow the construction of single power stages of 25 to 30 kW. The regulated sinusoidal distribution system has several advantages. With a regulated voltage, most ac/dc conversions involve rather simple transformer rectifier applications. A sinusoidal distribution system, when used in conjunction with zero crossing switching, represents a minimal source of EMI. The present state of 20 kHz power technology includes computer controls of voltage and/or frequency, low inductance cable, current limiting circuit protection, bi-directional power flow, and motor/generator operating using standard induction machines. A status update and description of each of these items and their significance is presented.

  5. High-throughput controllable generation of droplet arrays with low consumption

    Science.gov (United States)

    Lin, Yinyin; Wu, Zhongsheng; Gao, Yibo; Wu, Jinbo; Wen, Weijia

    2018-06-01

    We describe a controllable sliding method for fabricating millions of isolated femto- to nanoliter-sized droplets with defined volume, geometry and position and a speed of up to 375 kHz. In this work, without using a superhydrophobic or superoleophobic surface, arrays of droplets are instantly formed on the patterned substrate by sliding a strip of liquid, including water, low-surface-tension organic solvents and solution, along the substrate. To precisely control the volume of the droplets, we systemically investigate the effects of the size of the wettable pattern, the viscosity of the liquid and sliding speed, which were found to vary independently to tune the height and volume of the droplets. Through this method, we successfully fabricated an oriented single metal-organic framework crystal array with control over their XY positioning on the surface, as characterized by microscopy and X-ray diffraction (XRD) techniques.

  6. Removal of histone tails from nucleosome dissects the physical mechanisms of salt-induced aggregation, linker histone H1-induced compaction, and 30-nm fiber formation of the nucleosome array

    International Nuclear Information System (INIS)

    Hizume, Kohji; Nakai, Tonau; Araki, Sumiko; Prieto, Eloise; Yoshikawa, Kenichi; Takeyasu, Kunio

    2009-01-01

    In order to reveal the roles of histone tails in the formation of higher-order chromatin structures, we employed atomic force microscopy (AFM), and an in vitro reconstitution system to examine the properties of reconstituted chromatin composed of tail-less histones and a long DNA (106-kb plasmid) template. The tail-less nucleosomes did not aggregate at high salt concentrations or with an excess amount of core histones, in contrast with the behavior of nucleosomal arrays composed of nucleosomes containing normal, N-terminal tails. Analysis of our nucleosome distributions reveals that the attractive interaction between tail-less nucleosomes is weakened. Addition of linker histone H1 into the tail-less nucleosomal array failed to promote the formation of 30 nm chromatin fibers that are usually formed in the normal nucleosomal array. These results demonstrate that the attractive interaction between nucleosomes via histone tails plays a critical role in the formation of the uniform 30-nm chromatin fiber.

  7. Narrow linewidth short cavity Brillouin random laser based on Bragg grating array fiber and dynamical population inversion gratings

    Science.gov (United States)

    Popov, S. M.; Butov, O. V.; Chamorovski, Y. K.; Isaev, V. A.; Mégret, P.; Korobko, D. A.; Zolotovskii, I. O.; Fotiadi, A. A.

    2018-06-01

    We report on random lasing observed with 100-m-long fiber comprising an array of weak FBGs inscribed in the fiber core and uniformly distributed over the fiber length. Extended fluctuation-free oscilloscope traces highlight power dynamics typical for lasing. An additional piece of Er-doped fiber included into the laser cavity enables a stable laser generation with a linewidth narrower than 10 kHz.

  8. Perceptions of Pedagogical Formation Students about Web 2.0 Tools and Educational Practices

    Science.gov (United States)

    Avci Yücel, Ümmühan

    2017-01-01

    This study aims to examine pedagogical formation students' perceptions about Web 2.0 tools and educational practices. A case study approach forms the methodological framework of this study. This study was conducted with 42 pedagogical formation students of an Instructional Technology and Material Design course during the 2014-2015 spring semester.…

  9. Phase sensitive distributed vibration sensing based on ultraweak fiber Bragg grating array using double-pulse

    Science.gov (United States)

    Liu, Tao; Wang, Feng; Zhang, Xuping; Zhang, Lin; Yuan, Quan; Liu, Yu; Yan, Zhijun

    2017-08-01

    A distributed vibration sensing technique using double-optical-pulse based on phase-sensitive optical time-domain reflectometry (ϕ-OTDR) and an ultraweak fiber Bragg grating (UWFBG) array is proposed for the first time. The single-mode sensing fiber is integrated with the UWFBG array that has uniform spatial interval and ultraweak reflectivity. The relatively high reflectivity of the UWFBG, compared with the Rayleigh scattering, gains a high signal-to-noise ratio for the signal, which can make the system achieve the maximum detectable frequency limited by the round-trip time of the probe pulse in fiber. A corresponding experimental ϕ-OTDR system with a 4.5 km sensing fiber integrated with the UWFBG array was setup for the evaluation of the system performance. Distributed vibration sensing is successfully realized with spatial resolution of 50 m. The sensing range of the vibration frequency can cover from 3 Hz to 9 kHz.

  10. Optical tweezers with 2.5 kHz bandwidth video detection for single-colloid electrophoresis

    Science.gov (United States)

    Otto, Oliver; Gutsche, Christof; Kremer, Friedrich; Keyser, Ulrich F.

    2008-02-01

    We developed an optical tweezers setup to study the electrophoretic motion of colloids in an external electric field. The setup is based on standard components for illumination and video detection. Our video based optical tracking of the colloid motion has a time resolution of 0.2ms, resulting in a bandwidth of 2.5kHz. This enables calibration of the optical tweezers by Brownian motion without applying a quadrant photodetector. We demonstrate that our system has a spatial resolution of 0.5nm and a force sensitivity of 20fN using a Fourier algorithm to detect periodic oscillations of the trapped colloid caused by an external ac field. The electrophoretic mobility and zeta potential of a single colloid can be extracted in aqueous solution avoiding screening effects common for usual bulk measurements.

  11. Perancangan Prototipe Receiver Beacon Black Box Locator Acoustic 37,5 kHz Pingers

    Directory of Open Access Journals (Sweden)

    RUSTAMAJI RUSTAMAJI

    2016-01-01

    When an aircraft caught in an accident and crashes into the water, its location can be detected using a device called a receiver beacon black box locator acoustic (pingers receiver. The pingers receiver functioned as a reciever signal with 37,5 kHz ± 1 kHz frequency from trnasmitter pingers or Underwater Locator Beacon (ULB which is on air plane black blox. In this research made design pingers receiver composed of a series of  Band Pass Filter (BPF, envelope detector, audio amplifier, and loud speaker. The signal of 37,5 kHz ± 1 kHz  frequency sent by pingers transmitter will bereceived by pingers receiver, after which the signal will be processed by the Band Pass Filter (BPF circuit before being detected by envelope detector for take back the signal information which like pulse signal with 10ms width and 1 second interval as pingers signal tha can  be to  be heard by human ear. Based on the  design that  was made, the signal ouput generated by the prototype has a 14 ms width with 1 second interval. Keywords: pingers receiver, band pass filter (BPF, envelope detector, loud speaker.

  12. Fabrication of nanopore and nanoparticle arrays with high aspect ratio AAO masks

    Science.gov (United States)

    Li, Z. P.; Xu, Z. M.; Qu, X. P.; Wang, S. B.; Peng, J.; Mei, L. H.

    2017-03-01

    How to use high aspect ratio anodic aluminum oxide (AAO) membranes as an etching and evaporation mask is one of the unsolved problems in the application of nanostructured arrays. Here we describe the versatile utilizations of the highly ordered AAO membranes with a high aspect ratio of more than 20 used as universal masks for the formation of various nanostructure arrays on various substrates. The result shows that the fabricated nanopore and nanoparticle arrays of substrates inherit the regularity of the AAO membranes completely. The flat AAO substrates and uneven AAO frontages were attached to the Si substrates respectively as an etching mask, which demonstrates that the two kinds of replication, positive and negative, represent the replication of the mirroring of Si substrates relative to the flat AAO substrates and uneven AAO frontages. Our work is a breakthrough for the broad research field of surface nano-masking.

  13. High-channel-count, high-density microelectrode array for closed-loop investigation of neuronal networks.

    Science.gov (United States)

    Tsai, David; John, Esha; Chari, Tarun; Yuste, Rafael; Shepard, Kenneth

    2015-01-01

    We present a system for large-scale electrophysiological recording and stimulation of neural tissue with a planar topology. The recording system has 65,536 electrodes arranged in a 256 × 256 grid, with 25.5 μm pitch, and covering an area approximately 42.6 mm(2). The recording chain has 8.66 μV rms input-referred noise over a 100 ~ 10k Hz bandwidth while providing up to 66 dB of voltage gain. When recording from all electrodes in the array, it is capable of 10-kHz sampling per electrode. All electrodes can also perform patterned electrical microstimulation. The system produces ~ 1 GB/s of data when recording from the full array. To handle, store, and perform nearly real-time analyses of this large data stream, we developed a framework based around Xilinx FPGAs, Intel x86 CPUs and the NVIDIA Streaming Multiprocessors to interface with the electrode array.

  14. Stereoscopic Planar Laser-Induced Fluorescence Imaging at 500 kHz

    Science.gov (United States)

    Medford, Taylor L.; Danehy, Paul M.; Jones, Stephen B.; Jiang, N.; Webster, M.; Lempert, Walter; Miller, J.; Meyer, T.

    2011-01-01

    A new measurement technique for obtaining time- and spatially-resolved image sequences in hypersonic flows is developed. Nitric-oxide planar laser-induced fluorescence (NO PLIF) has previously been used to investigate transition from laminar to turbulent flow in hypersonic boundary layers using both planar and volumetric imaging capabilities. Low flow rates of NO were typically seeded into the flow, minimally perturbing the flow. The volumetric imaging was performed at a measurement rate of 10 Hz using a thick planar laser sheet that excited NO fluorescence. The fluorescence was captured by a pair of cameras having slightly different views of the flow. Subsequent stereoscopic reconstruction of these images allowed the three-dimensional flow structures to be viewed. In the current paper, this approach has been extended to 50,000 times higher repetition rates. A laser operating at 500 kHz excites the seeded NO molecules, and a camera, synchronized with the laser and fitted with a beam-splitting assembly, acquires two separate images of the flow. The resulting stereoscopic images provide three-dimensional flow visualizations at 500 kHz for the first time. The 200 ns exposure time in each frame is fast enough to freeze the flow while the 500 kHz repetition rate is fast enough to time-resolve changes in the flow being studied. This method is applied to visualize the evolving hypersonic flow structures that propagate downstream of a discrete protuberance attached to a flat plate. The technique was demonstrated in the NASA Langley Research Center s 31-Inch Mach 10 Air Tunnel facility. Different tunnel Reynolds number conditions, NO flow rates and two different cylindrical protuberance heights were investigated. The location of the onset of flow unsteadiness, an indicator of transition, was observed to move downstream during the tunnel runs, coinciding with an increase in the model temperature.

  15. A Spectroscopic Comparison of Femtosecond Laser Modified Fused Silica using kHz and MHz Laser Systems.

    Energy Technology Data Exchange (ETDEWEB)

    Reichman, W J; Krol, D M; Shah, L; Yoshino, F; Arai, A; Eaton, S M; Herman, P R

    2005-09-29

    Waveguides were written in fused silica using both a femtosecond fiber laser with a 1 MHz pulse repetition rate and a femtosecond amplified Ti:sapphire laser with a 1 kHz repetition rate. Confocal Raman and fluorescence microscopy were used to study structural changes in the waveguides written with both systems. A broad fluorescence band, centered at 650 nm, associated with non-bridging oxygen hole center (NBOHC) defects was observed after waveguide fabrication with the MHz laser. With the kHz laser system these defects were only observed for pulse energies above 1 {mu}J. Far fewer NBOHC defects were formed with the MHz laser than with kHz writing, possibly due to thermal annealing driven by heat accumulation effects at 1 MHz. When the kHz laser was used with pulse energies below 1 {mu}J, the predominant fluorescence was centered at 550 nm, a band assigned to the presence of silicon clusters (E{prime}{sub {delta}}). We also observed an increase in the intensity of the 605 cm{sup -1} Raman peak relative to the total Raman intensity, corresponding to an increase in the concentration of 3-membered rings in the lines fabricated with both laser systems.

  16. Gold nanoparticle array formation on dimpled Ta templates using pulsed laser-induced thin film dewetting.

    Science.gov (United States)

    El-Sayed, Hany A; Horwood, Corie A; Owusu-Ansah, Ebenezer; Shi, Yujun J; Birss, Viola I

    2015-04-28

    Here we show that pulsed laser-induced dewetting (PLiD) of a thin Au metallic film on a nano-scale ordered dimpled tantalum (DT) surface results in the formation of a high quality Au nanoparticle (NP) array. In contrast to thermal dewetting, PLiD does not result in deformation of the substrate, even when the Au film is heated to above its melting point. PLiD causes local heating of only the metal film and thus thermal oxidation of the Ta substrate can be avoided, also because of the high vacuum (low pO2) environment employed. Therefore, this technique can potentially be used to fabricate NP arrays composed of high melting point metals, such as Pt, not previously possible using conventional thermal annealing methods. We also show that the Au NPs formed by PLiD are more spherical in shape than those formed by thermal dewetting, likely demonstrating a different dewetting mechanism in the two cases. As the metallic NPs formed on DT templates are electrochemically addressable, a longer-term objective of this work is to determine the effect of NP size and shape (formed by laser vs. thermal dewetting) on their electrocatalytic properties.

  17. Voltage-Ratio Calibration System up to 50 kHz

    Science.gov (United States)

    Trigo, Leonardo; Slomovitz, Daniel; Faverio, Carlos; Kyriazis, Gregory

    2018-03-01

    This paper describes a voltage-ratio measuring system that can be used up to 50 kHz with high accuracy. It is based on two Keysight 3458A digital multimeters, working in DCV sampling mode. An external trigger based on a rubidium clock, drives both digital multimeters. It is applied to the calibration of a set of voltage dividers with primary voltages from 4 V to 1024 V.

  18. Predicting neutron star spins from twin kHz QPOs

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We briefly review the proposed relations between the frequencies of twin kilohertz quasi-periodic oscillations(kHz QPOs) and the spin frequencies in neutron star low-mass X-ray binaries(NSLMXBs).To test the validity of the proposed models,we estimate the spin frequencies under these theoretical relations and compare them with the measured ones.It seems that magnetohydrodynamic(MHD) oscillations are more promising to account for the kHz QPOs.

  19. Using bedding in a test environment critically affects 50-kHz ultrasonic vocalizations in laboratory rats.

    Science.gov (United States)

    Natusch, C; Schwarting, R K W

    2010-09-01

    Rats utter distinct classes of ultrasonic vocalizations depending on their developmental stage, current state, and situational factors. One class, comprising the so-called 50-kHz calls, is typical for situations where rats are anticipating or actually experiencing rewarding stimuli, like being tickled by an experimenter, or when treated with drugs of abuse, such as the psychostimulant amphetamine. Furthermore, rats emit 50-kHz calls when exposed to a clean housing cage. Here, we show that such vocalization effects can depend on subtle details of the testing situation, namely the presence of fresh rodent bedding. Actually, we found that adult males vocalize more in bedded cages than in bare ones. Also, two experiments showed that adult rats emitted more 50-kHz calls when tickled on fresh bedding. Furthermore, ip amphetamine led to more 50-kHz vocalization in activity boxes containing such bedding as compared to bare ones. The analysis of psychomotor activation did not yield such group differences in case of locomotion and centre time, except for rearing duration in rats tested on bedding. Also, the temporal profile of vocalization did not parallel that of behavioural activation, since the effects on vocalization peaked and started to decline again before those of psychomotor activation. Therefore, 50-kHz calls are not a simple correlate of psychomotor activation. A final experiment with a choice procedure showed that rats prefer bedded conditions. Overall, we assume that bedded environments induce a positive affective state, which increases the likelihood of 50-kHz calling. Based on these findings, we recommend that contextual factors, like bedding, should receive more research attention, since they can apparently decrease the aversiveness of a testing situation. Also, we recommend to more routinely measure rat ultrasonic vocalization, especially when studying emotion and motivation, since this analysis can provide information about the subject's status, which may

  20. Performance measurements of hybrid PIN diode arrays

    International Nuclear Information System (INIS)

    Jernigan, J.G.; Arens, J.F.; Collins, T.; Herring, J.; Shapiro, S.L.; Wilburn, C.D.

    1990-05-01

    We report on the successful effort to develop hybrid PIN diode arrays and to demonstrate their potential as components of vertex detectors. Hybrid pixel arrays have been fabricated by the Hughes Aircraft Co. by bump bonding readout chips developed by Hughes to an array of PIN diodes manufactured by Micron Semiconductor Inc. These hybrid pixel arrays were constructed in two configurations. One array format having 10 x 64 pixels, each 120 μm square, and the other format having 256 x 256 pixels, each 30 μm square. In both cases, the thickness of the PIN diode layer is 300 μm. Measurements of detector performance show that excellent position resolution can be achieved by interpolation. By determining the centroid of the charge cloud which spreads charge into a number of neighboring pixels, a spatial resolution of a few microns has been attained. The noise has been measured to be about 300 electrons (rms) at room temperature, as expected from KTC and dark current considerations, yielding a signal-to-noise ratio of about 100 for minimum ionizing particles. 4 refs., 13 figs

  1. High-frequency (8 to 16 kHz) reference thresholds and intrasubject threshold variability relative to ototoxicity criteria using a Sennheiser HDA 200 earphone.

    Science.gov (United States)

    Frank, T

    2001-04-01

    The first purpose of this study was to determine high-frequency (8 to 16 kHz) thresholds for standardizing reference equivalent threshold sound pressure levels (RETSPLs) for a Sennheiser HDA 200 earphone. The second and perhaps more important purpose of this study was to determine whether repeated high-frequency thresholds using a Sennheiser HDA 200 earphone had a lower intrasubject threshold variability than the ASHA 1994 significant threshold shift criteria for ototoxicity. High-frequency thresholds (8 to 16 kHz) were obtained for 100 (50 male, 50 female) normally hearing (0.25 to 8 kHz) young adults (mean age of 21.2 yr) in four separate test sessions using a Sennheiser HDA 200 earphone. The mean and median high-frequency thresholds were similar for each test session and increased as frequency increased. At each frequency, the high-frequency thresholds were not significantly (p > 0.05) different for gender, test ear, or test session. The median thresholds at each frequency were similar to the 1998 interim ISO RETSPLs; however, large standard deviations and wide threshold distributions indicated very high intersubject threshold variability, especially at 14 and 16 kHz. Threshold repeatability was determined by finding the threshold differences between each possible test session comparison (N = 6). About 98% of all of the threshold differences were within a clinically acceptable range of +/-10 dB from 8 to 14 kHz. The threshold differences between each subject's second, third, and fourth minus their first test session were also found to determine whether intrasubject threshold variability was less than the ASHA 1994 criteria for determining a significant threshold shift due to ototoxicity. The results indicated a false-positive rate of 0% for a threshold shift > or = 20 dB at any frequency and a false-positive rate of 2% for a threshold shift >10 dB at two consecutive frequencies. This study verified that the output of high-frequency audiometers at 0 dB HL using

  2. Plasma-assisted self-formation of nanotip arrays on the surface of Cu(In,Ga)Se{sub 2} thin films

    Energy Technology Data Exchange (ETDEWEB)

    Zimin, Sergey P.; Mokrov, Dmitry A. [Yaroslavl State University (Russian Federation); Gorlachev, Egor S.; Amirov, Ildar I.; Naumov, Viktor V. [Institute of Physics and Technology, Russian Academy of Sciences, Yaroslavl (Russian Federation); Gremenok, Valery F. [Scientific-Practical Materials Research Center, NAS of Belarus, Minsk (Belarus); Bente, Klaus [Applied Mineralogy, University Tuebingen (Germany); Kim, Woo Y. [Fusion Research Center, Hoseo University, Asan-City (Korea, Republic of)

    2017-06-15

    In this paper, we report on the phenomenon of nanostructure self-formation on the surface of Cu(In,Ga)Se{sub 2} (CIGS) thin films during inductively coupled argon plasma treatment with its duration varied from 10 to 120 s. The initial films were grown on glass substrates using the selenization technique. During the CIGS film surface treatment in the high-density low-pressure radio-frequency inductively coupled argon plasma there took place a formation of arrays of uniform vertical nanostructures, which shape with increasing processing duration changed from nanocones to nanorods and back to nanocones. A model of the nanotip plasma-assisted self-formation associated with the implementation of micromasking and vapor-liquid-solid mechanisms involving metallic In-Ga (In-Ga-Cu) liquid alloy droplets is proposed. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Magnetically-coupled microcalorimeter arrays for x-ray astrophysics

    Science.gov (United States)

    Bandler, Simon

    The "X-ray Surveyor" has been listed by NASA as one of the four major large mission concepts to be studied in the next Astrophysics Decadal Review in its preliminary list of large concepts. One of the key instruments on such a mission would be a very large format X-ray microcalorimeter array, with an array size of greater than 100 thousand pixels. Magnetically-coupled microcalorimeters (MCC) are one of the technologies with the greatest potential to meet the requirements of this mission, and this proposal is one to carry out research specifically to reach the goals of this vision. The "X-ray Surveyor" is a concept for a future mission that will make X-ray observations that are instrumental to understanding the quickly emerging population of galaxies and supermassive black holes at z ~10. The observations will trace the formation of galaxies and their assembly into large-scale structures starting from the earliest possible epochs. This mission would be observing baryons and large-scale physical processes outside of the very densest regions in the local Universe. This can be achieved with an X-ray observatory with similar angular resolution as Chandra but with significantly improved optic area and detector sensitivity. Chandra-scale angular resolution (1" or better) is essential in building more powerful, higher throughput observatories to avoid source confusion and remain photon-limited rather than background-limited. A prime consideration for the microcalorimeter camera on this type of mission is maintaining ~ 1 arcsec spatial resolution over the largest possible field of view, even if this means a slight trade-off against the spectral resolution. A uniform array of 1" pixels covering at least 5'x5' field of view is desired. To reduce the number of sensors read out, in geometries where extremely fine pitch (~50 microns) is desired, the most promising technologies are those in which a thermal sensor such an MCC can read out a sub-array of 20-25 individual 1'

  4. Guidelines for limiting exposure to time-varying electric and magnetic fields (1 Hz to 100 kHz)

    International Nuclear Information System (INIS)

    Anon.

    2011-01-01

    This paper is the French translation of an article from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) Guidelines, entitled 'Guidelines for Limiting Exposure to Time-Varying Electric and Magnetic Fields (1 Hz To 100 kHz)'. In This document, guidelines are established for the protection of humans exposed to electric and magnetic fields in the low-frequency range of the electromagnetic spectrum. The general principles for the development of ICNIRP guidelines are published elsewhere (ICNIRP 2002). For the purpose of this document, the low-frequency range extends from 1 Hz to 100 kHz. Above 100 kHz, effects such as heating need to be considered, which are covered by other ICNIRP guidelines. However, in the frequency range from 100 kHz up to approximately 10 MHz protection from both, low frequency effects on the nervous system as well as high frequency effects need to be considered depending on exposure conditions. Therefore, some guidance in this document is extended to 10 MHz to cover the nervous system effects in this frequency range. Guidelines for static magnetic fields have been issued in a separate document (ICNIRP 2009). Guidelines applicable to movement-induced electric fields or time-varying magnetic fields up to 1 Hz will be published separately. This publication replaces the low-frequency part of the 1998 guidelines (ICNIRP 1998). ICNIRP is currently revising the guidelines for the high-frequency portion of the spectrum (above 100 kHz). (authors)

  5. Monolithic blue LED series arrays for high-voltage AC operation

    Energy Technology Data Exchange (ETDEWEB)

    Ao, Jin-Ping [Satellite Venture Business Laboratory, University of Tokushima, Tokushima 770-8506 (Japan); Sato, Hisao; Mizobuchi, Takashi; Morioka, Kenji; Kawano, Shunsuke; Muramoto, Yoshihiko; Sato, Daisuke; Sakai, Shiro [Nitride Semiconductor Co. Ltd., Naruto, Tokushima 771-0360 (Japan); Lee, Young-Bae; Ohno, Yasuo [Department of Electrical and Electronic Engineering, University of Tokushima, Tokushima 770-8506 (Japan)

    2002-12-16

    Design and fabrication of monolithic blue LED series arrays that can be operated under high ac voltage are described. Several LEDs, such as 3, 7, and 20, are connected in series and in parallel to meet ac operation. The chip size of a single device is 150 {mu}m x 120 {mu}m and the total size is 1.1 mm x 1 mm for a 40(20+20) LED array. Deep dry etching was performed as device isolation. Two-layer interconnection and air bridge are utilized to connect the devices in an array. The monolithic series array exhibit the expected operation function under dc and ac bias. The output power and forward voltage are almost proportional to LED numbers connected in series. On-wafer measurement shows that the output power is 40 mW for 40(20+20) LED array under ac 72 V. (Abstract Copyright [2002], Wiley Periodicals, Inc.)

  6. Large aperture deformable mirror with a transferred single-crystal silicon membrane actuated using large-stroke PZT Unimorph Actuators

    Science.gov (United States)

    Hishinumat, Yoshikazu; Yang, Eui - Hyeok (EH)

    2005-01-01

    We have demonstrated a large aperture (50 mm x 50 mm) continuous membrane deformable mirror (DM) with a large-stroke piezoelectric unimorph actuator array. The DM consists of a continuous, large aperture, silicon membrane 'transferred' in its entirety onto a 20 x 20 piezoelectric unimorph actuator array. A PZT unimorph actuator, 2.5 mm in diameter with optimized PZT/Si thickness and design showed a deflection of 5.7 [m at 20V. An assembled DM showed an operating frequency bandwidth of 30 kHz and influence function of approximately 30%.

  7. Test-retest reliability of pure-tone thresholds from 0.5 to 16 kHz using Sennheiser HDA 200 and Etymotic Research ER-2 earphones.

    Science.gov (United States)

    Schmuziger, Nicolas; Probst, Rudolf; Smurzynski, Jacek

    2004-04-01

    The purposes of the study were: (1) To evaluate the intrasession test-retest reliability of pure-tone thresholds measured in the 0.5-16 kHz frequency range for a group of otologically healthy subjects using Sennheiser HDA 200 circumaural and Etymotic Research ER-2 insert earphones and (2) to compare the data with existing criteria of significant threshold shifts related to ototoxicity and noise-induced hearing loss. Auditory thresholds in the frequency range from 0.5 to 6 kHz and in the extended high-frequency range from 8 to 16 kHz were measured in one ear of 138 otologically healthy subjects (77 women, 61 men; mean age, 24.4 yr; range, 12-51 yr) using HDA 200 and ER-2 earphones. For each subject, measurements of thresholds were obtained twice for both transducers during the same test session. For analysis, the extended high-frequency range from 8 to 16 kHz was subdivided into 8 to 12.5 and 14 to 16 kHz ranges. Data for each frequency and frequency range were analyzed separately. There were no significant differences in repeatability for the two transducer types for all frequency ranges. The intrasession variability increased slightly, but significantly, as frequency increased with the greatest amount of variability in the 14 to 16 kHz range. Analyzing each individual frequency, variability was increased particularly at 16 kHz. At each individual frequency and for both transducer types, intrasession test-retest repeatability from 0.5 to 6 kHz and 8 to 16 kHz was within 10 dB for >99% and >94% of measurements, respectively. The results indicated a false-positive rate of HDA 200. Repeatability was similar for both transducer types. Intrasession test-retest repeatability from 0.5 to 12.5 kHz at each individual frequency including the frequency range susceptible to noise-induced hearing loss was excellent for both transducers. Repeatability was slightly, but significantly poorer in the frequency range from 14 to 16 kHz compared with the frequency ranges from 0.5 to 6

  8. Formation of patterned arrays of Au nanoparticles on SiC surface by template confined dewetting of normal and oblique deposited nanoscale films

    Energy Technology Data Exchange (ETDEWEB)

    Ruffino, F., E-mail: francesco.ruffino@ct.infn.it; Grimaldi, M.G.

    2013-06-01

    We report on the formation of patterned arrays of Au nanoparticles (NPs) on 6H SiC surface. To this end, we exploit the thermal-induced dewetting properties of a template confined deposited nanoscale Au film. In this approach, the Au surface pattern order, on the SiC substrate, is established by a template confined deposition using a micrometric template. Then, a dewetting process of the patterned Au film is induced by thermal processes. We compare the results, about the patterns formation, obtained for normal and oblique deposited Au films. We show that the normal and oblique depositions, through the same template, originate different patterns of the Au film. As a consequence of these different starting patterns, after the thermal processes, different patterns for the arrays of NPs originating from the dewetting mechanisms are obtained. For each fixed deposition angle α, the pattern evolution is analyzed, by scanning electron microscopy, as a function of the annealing time at 1173 K (900 °C). From these analyses, quantitative evaluations on the NPs size evolution are drawn. - Highlights: • Micrometric template-confined nanoscale gold films are deposited on silicon carbide. • The dewetting process of template-confined gold films on silicon carbide is studied. • Comparison of dewetting process of normal and oblique deposited gold films is drawn. • Patterned arrays of gold nanoparticles on silicon carbide surface are produced.

  9. Formation of patterned arrays of Au nanoparticles on SiC surface by template confined dewetting of normal and oblique deposited nanoscale films

    International Nuclear Information System (INIS)

    Ruffino, F.; Grimaldi, M.G.

    2013-01-01

    We report on the formation of patterned arrays of Au nanoparticles (NPs) on 6H SiC surface. To this end, we exploit the thermal-induced dewetting properties of a template confined deposited nanoscale Au film. In this approach, the Au surface pattern order, on the SiC substrate, is established by a template confined deposition using a micrometric template. Then, a dewetting process of the patterned Au film is induced by thermal processes. We compare the results, about the patterns formation, obtained for normal and oblique deposited Au films. We show that the normal and oblique depositions, through the same template, originate different patterns of the Au film. As a consequence of these different starting patterns, after the thermal processes, different patterns for the arrays of NPs originating from the dewetting mechanisms are obtained. For each fixed deposition angle α, the pattern evolution is analyzed, by scanning electron microscopy, as a function of the annealing time at 1173 K (900 °C). From these analyses, quantitative evaluations on the NPs size evolution are drawn. - Highlights: • Micrometric template-confined nanoscale gold films are deposited on silicon carbide. • The dewetting process of template-confined gold films on silicon carbide is studied. • Comparison of dewetting process of normal and oblique deposited gold films is drawn. • Patterned arrays of gold nanoparticles on silicon carbide surface are produced

  10. Dynamical formation of spatially localized arrays of aligned nanowires in plastic films with magnetic anisotropy.

    Science.gov (United States)

    Fragouli, Despina; Buonsanti, Raffaella; Bertoni, Giovanni; Sangregorio, Claudio; Innocenti, Claudia; Falqui, Andrea; Gatteschi, Dante; Cozzoli, Pantaleo Davide; Athanassiou, Athanassia; Cingolani, Roberto

    2010-04-27

    We present a simple technique for magnetic-field-induced formation, assembling, and positioning of magnetic nanowires in a polymer film. Starting from a polymer/iron oxide nanoparticle casted solution that is allowed to dry along with the application of a weak magnetic field, nanocomposite films incorporating aligned nanocrystal-built nanowire arrays are obtained. The control of the dimensions of the nanowires and of their localization across the polymer matrix is achieved by varying the duration of the applied magnetic field, in combination with the evaporation dynamics. These multifunctional anisotropic free-standing nanocomposite films, which demonstrate high magnetic anisotropy, can be used in a wide field of technological applications, ranging from sensors to microfluidics and magnetic devices.

  11. Functions of KLK4 and MMP-20 in dental enamel formation

    Science.gov (United States)

    Lu, Yuhe; Papagerakis, Petros; Yamakoshi, Yasuo; Hu, Jan C-C.; Bartlett, John D.; Simmer, James P.

    2009-01-01

    Two proteases are secreted into the enamel matrix of developing teeth. The early protease is enamelysin (MMP-20). The late protease is kallikrein 4 (KLK4). Mutations in MMP20 and KLK4 both cause autosomal recessive amelogenesis imperfecta, a condition featuring soft, porous enamel containing residual protein. MMP-20 is secreted along with enamel proteins by secretory stage ameloblasts. Enamel protein cleavage products accumulate in the space between the crystal ribbons, helping to support them. MMP-20 steadily cleaves accumulated enamel proteins, so their concentration decreases with depth. Kallikrein 4 is secreted by transition and maturation stage ameloblasts. KLK4 aggressively degrades the retained organic matrix following the termination of enamel protein secretion. The principle functions of MMP-20 and KLK4 in dental enamel formation are to facilitate the orderly replacement of organic matrix with mineral, generating an enamel layer that is harder, less porous, and unstained by retained enamel proteins. PMID:18627287

  12. Study of Plasma Flow Modes in Imploding Nested Arrays

    Science.gov (United States)

    Mitrofanov, K. N.; Aleksandrov, V. V.; Gritsuk, A. N.; Branitsky, A. V.; Frolov, I. N.; Grabovski, E. V.; Sasorov, P. V.; Ol'khovskaya, O. G.; Zaitsev, V. I.

    2018-02-01

    Results from experimental studies of implosion of nested wire and fiber arrays at currents of up to 4 MA at the Angara-5-1 facility are presented. Depending on the ratio between the radii of the inner and outer arrays, different modes of the plasma flow in the space between the inner and outer arrays were implemented: the sub-Alfvénic ( V r V A ) modes and a mode with the formation of the transition shock wave (SW) region between the cascades. By varying the material of the outer array (tungsten wires or kapron fibers), it is shown that the plasma flow mode between the inner and outer arrays depends on the ratio between the plasma production rates ṁ in / ṁ out in the inner and outer arrays. The obtained experimental results are compared with the results of one-dimensional MHD simulation of the plasma flow between the arrays. Stable implosion of the inner array plasma was observed in experiments with combined nested arrays consisting of a fiber outer array and a tungsten inner array. The growth rates of magnetic Rayleigh-Taylor (MRT) instability in the inner array plasma at different numbers of fibers in the outer array and different ratios between the radii of the inner and outer arrays are compared. Suppression of MRT instability during the implosion of the inner array plasma results in the formation of a stable compact Z-pinch and generation of a soft X-ray pulse. A possible scenario of interaction between the plasmas of the inner and outer arrays is offered. The stability of the inner array plasma in the stage of final compression depends on the character of interaction of plasma jets from the outer array with the magnetic field of the inner array.

  13. Circumferential lesion formation around the pulmonary veins in the left atrium with focused ultrasound using a 2D-array endoesophageal device: a numerical study

    Energy Technology Data Exchange (ETDEWEB)

    Pichardo, Samuel; Hynynen, Kullervo [Imaging Research-Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room C713, Toronto, ON M4N 3M5 (Canada)

    2007-08-21

    Atrial fibrillation (AF) is the most frequently sustained cardiac arrhythmia affecting humans. The electrical isolation by ablation of the pulmonary veins (PVs) in the left atrium (LA) of the heart has been proven as an effective cure of AF. The ablation consists mainly in the formation of a localized circumferential thermal coagulation of the cardiac tissue surrounding the PVs. In the present numerical study, the feasibility of producing the required circumferential lesion with an endoesophageal ultrasound probe is investigated. The probe operates at 1 MHz and consists of a 2D array with enough elements (114 x 20) to steer the acoustic field electronically in a volume comparable to the LA. Realistic anatomical conditions of the thorax were considered from the segmentation of histological images of the thorax. The cardiac muscle and the blood-filled cavities in the heart were identified and considered in the sound propagation and thermal models. The influence of different conditions of the thermal sinking in the LA chamber was also studied. The circumferential ablation of the PVs was achieved by the sum of individual lesions induced with the proposed device. Different scenarios of lesion formation were considered where ultrasound exposures (1, 2, 5 and 10 s) were combined with maximal peak temperatures (60, 70 and 80 {sup 0}C). The results of this numerical study allowed identifying the limits and best conditions for controlled lesion formation in the LA using the proposed device. A controlled situation for the lesion formation surrounding the PVs was obtained when the targets were located within a distance from the device in the range of 26 {+-} 7 mm. When combined with a maximal temperature of 70 {sup 0}C and an exposure time between 5 and 10 s, this distance ensured preservation of the esophageal structures, controlled lesion formation and delivery of an acoustic intensity at the transducer surface that is compatible with existing materials. With a peak

  14. Configurational Reassignment and Improved Preparation of the Competitive IL-6 Receptor Antagonist 20R,21R-Epoxyresibufogenin-3-formate

    Science.gov (United States)

    Boos, Terrence L.; Cheng, Kejun; Greiner, Elisabeth; Deschamps, Jeffrey R.; Jacobson, Arthur E.; Rice, Kenner C.

    2012-01-01

    20R,21R-Epoxyresibufogenin-3-formate (1) and 20S,21S-epoxyresibufogenin-3-formate (2) were synthesized from commercial resibufogenin (3) using known procedures. The major product (1) was dextrorotatory, as was the major product from the reported synthesis of epoxyresibufogenin-3-formate; however, the literature (+)-compound was assigned the 20S,21S-configuration based on NMR data. We have now unequivocally determined, using single-crystal X-ray structure analyses of the major and minor products of the synthesis and of their derivatives, that the major product from the synthesis was (+)-20R,21R-epoxyresibufogenin-3-formate (1). Our minor synthetic product was determined to have the (-)-20S,21S-configuration (2). The (+)-20R,21R-compound 1 has been found to have high affinity for the IL-6 receptor and to act as an IL-6 antagonist. A greatly improved synthesis of 1 was achieved through oxidation of preformed resibufogenin-3-formate. This has enabled us to prepare, from the very expensive commercial resibufogenin, considerably larger quantities of 1, the only known non-peptide small molecule IL-6 antagonist. PMID:22360661

  15. Polarization measurements made on LFRA and OASIS emitter arrays

    Science.gov (United States)

    Geske, Jon; Sparkman, Kevin; Oleson, Jim; Laveigne, Joe; Sieglinger, Breck; Marlow, Steve; Lowry, Heard; Burns, James

    2008-04-01

    Polarization is increasingly being considered as a method of discrimination in passive sensing applications. In this paper the degree of polarization of the thermal emission from the emitter arrays of two new Santa Barbara Infrared (SBIR) micro-bolometer resistor array scene projectors was characterized at ambient temperature and at 77 K. The emitter arrays characterized were from the Large Format Resistive Array (LFRA) and the Optimized Arrays for Space-Background Infrared Simulation (OASIS) scene projectors. This paper reports the results of this testing.

  16. Development of multi-channel gated integrator and PXI-DAQ system for nuclear detector arrays

    International Nuclear Information System (INIS)

    Kong Jie; Su Hong; Chen Zhiqiang; Dong Chengfu; Qian Yi; Gao Shanshan; Zhou Chaoyang; Lu Wan; Ye Ruiping; Ma Junbing

    2010-01-01

    A multi-channel gated integrator and PXI based data acquisition system have been developed for nuclear detector arrays with hundreds of detector units. The multi-channel gated integrator can be controlled by a programmable GI controller. The PXI-DAQ system consists of NI PXI-1033 chassis with several PXI-DAQ cards. The system software has a user-friendly GUI which is written in C language using LabWindows/CVI under Windows XP operating system. The performance of the PXI-DAQ system is very reliable and capable of handling event rate up to 40 kHz.

  17. Final report on the scientific and engineering design of a soft X-ray diode array diagnostic system for JET (KJ 1)

    International Nuclear Information System (INIS)

    Fahrbach, H.U.; Goss, H.; Harmeyer, E.; Schramm, G.

    1982-07-01

    This report describes the Soft-X-Ray Diode Array Diagnostic System for JET. It was designed by the IPP under an Article 14 contract for Phase I. The diagnostics will be capable of measuring the Soft-X-ray emission from H and D plasmas in JET with high resolution in space and time. Two slot-hole cameras with 150 detectors viewing the same toroidal cross-section of the plasma are foreseen. Thin beryllium and aluminium filters in the line of sight of the detectors allow simultaneous measurements within different limits of the X-ray spectrum. Heavy shielding against neutron and gamma radiation is provided in order to reduce radiation induced signals and to increase detector lifetimes. The signals of 100 detectors can be simultaneously sampled with a sampling rate variable up to 250 KHz and stored in 12 bit memories of about 20 Kwords size. (orig.)

  18. Burr formation detector for fiber laser cutting based on a photodiode sensor system

    Science.gov (United States)

    Schleier, Max; Adelmann, Benedikt; Neumeier, Benedikt; Hellmann, Ralf

    2017-11-01

    We report a unique sensor system based on a InGaAs photodiode to detect the formation of burr during near infrared fiber laser cutting. The sensor approach encompasses the measurement of the thermal radiation form the process zone, optical filtering, digitalized sampling at 20 kHz, digital filtering using an elliptical band-pass filter 12th order and calculation of the standard deviation. We find a linear correlation between the deduced sensor signal and the generated burr height with this functionality being experimentally confirmed for laser cutting of mild and stainless steel of different thicknesses. The underlying mechanism of this transducer concept is attributed to the melt flow dynamics inside the cut kerf.

  19. Application of phased array technology for identification of low frequency noise sources

    Energy Technology Data Exchange (ETDEWEB)

    Hugo E. Camargo; Patricio A. Ravetta; Ricardo A. Burdisso; Adam K. Smith [NIOSH (United States)

    2009-12-15

    A study conducted by the National Institute for Occupational Safety and Health (NIOSH) revealed that 90% of coal miners have hearing impairment by age 50, compared to only 10% of those not exposed to occupational noise. According to the Mine Safety and Health Administration (MSHA), Continuous Mining Machine (CM) operators account for 30% of workers exposed to noise doses exceeding the Permissible Exposure Level (PEL). In this context, NIOSH is conducting research to identify and control dominant noise sources in CMs. Previous noise source identification was performed using a Bruel & Kjaer (B&K) 1.92-m diameter, 42-microphone phased array. These measurements revealed that the impacts from the conveyor chain onto the tail roller, and the impacts from the conveyor chain onto the upper deck are the dominant noise sources at the tail-section of the CM. The objectives of the work presented in this paper were: (1) To rank the noise radiated by the different sections of the conveyor, and (2) to determine the effect of a urethane-coated tail roller on the noise radiated by the tail-section. This test was conducted using an Acoustical and Vibrations Engineering Consultants (AVEC) 3.5-m diameter, 121-microphone phased array. The results from this new test show that a urethane-coated tail roller yields reductions in the tail-section of 2 to 8 dB in Sound Pressure Level in the frequency range of 1 kHz to 5 kHz. However, integration of the acoustic maps shows that the front-section and mid-section of the conveyor also contain dominant noise sources. Therefore, a urethane-coated tail roller in combination with a chain with urethane-coated flights that reduces the noise sources in the front and mid sections of the conveyor is required to yield a significant noise reduction on the CM operator's overall exposure. These results show the applicability of phased array technology for low frequency noise source identification.

  20. High-energy kHz mid-IR tunable PPSLT-based OPO pumped at 1064 nm

    Energy Technology Data Exchange (ETDEWEB)

    Gaydardzhiev, A; Chuchumishev, D; Draganov, D; Buchvarov, I [Department of Physics, Sofia University, 5 James Bourchier Blvd., BG-1164, Sofia (Bulgaria)

    2012-06-30

    We report a single-frequency sub-nanosecond optical parametric oscillator (OPO) based on periodically poled stoichiometric lithium tantalate (PPSLT), pumped by a 1064-nm amplified microchip laser at a repetition rate of 0.5 kHz. Using a 11-mm-long PPSLT crystal polled with three different domain periods (30.2, 30.3, 30.4 {mu}m) and changing the temperature of the crystal from 20 Degree-Sign C to 265 Degree-Sign C, we have achieved wavelength tuning between 2990 nm and 3500 nm. The high nonlinearity of the used medium and the large aperture (2 mm) ensure the maximum idler output energy of {approx}0.5 mJ in the whole tuning range, corresponding to average {approx}10.5 % idler conversion efficiency and {approx}250 mW of average power. Sub-nanosecond pulse durations have been obtained for the idler at 0.88-ns pulse duration of the pump.

  1. Experimental studies of Z-pinches of mixed wire array with aluminum and tungsten

    International Nuclear Information System (INIS)

    Ning Cheng; Li Zhenghong; Hua Xinsheng; Xu Rongkun; Peng Xianjue; Xu Zeping; Yang Jianlun; Guo Cun; Jiang Shilun; Feng Shuping; Yang Libing; Yan Chengli; Song Fengjun; Smirnov, V.P.; Kalinin, Yu.G.; Kingsep, A.S.; Chernenko, A.S.; Grabovsky, E.V.

    2004-01-01

    In the form of joint experiment between China and Russia, the experimental studies of Z-pinches of mixed wire array of aluminum (A1) and tungsten (W) were carried out on S-300 generator, which was located on Kurchatov Institute of Russia. The experimental results were compared with those of single A1 array and single W array, respectively. There are obvious difference between mixed one and single one in their photon spectral distributions. The intensity of K-series emission lines from the mixed wire array Z-pinch is lower than that from single A1 array. The radiated lines with wavelengths less than 1.6 nm were not found in single W array Z-pinches. In the Z-pinch processes, the area radiating x-rays in mixed wire array is smaller than that of single A1 array, but is slightly lower than that from single W array. The FWHM of x-ray pulse with a maximal power 0.3-0.5 TW and total energy 10-20 kJ is about 25 ns, which radiated from Z-pinches with a radial convergence of 4-5 on S-300 generator. The shadow photograph of the mixed wire-array Z-pinch plasma by laser probe shows that the core-corona configuration was formed and the corona was moving toward the center axis during the wire-array plasma formation, that the interface of the plasma is not clear, and that there are a number structures inside. They also suggests that there was an obvious development of Magneto Rayleigh-Taylor instability in the Z-pinch process as well

  2. Modulation of Rat 50-kHz Ultrasonic Vocalizations by Glucocorticoid Signaling: Possible Relevance to Reward and Motivation.

    Science.gov (United States)

    Simola, Nicola; Paci, Elena; Serra, Marcello; Costa, Giulia; Morelli, Micaela

    2018-01-01

    Rats emit 50-kHz ultrasonic vocalizations (USVs) to communicate positive emotional states, and these USVs are increasingly being investigated in preclinical studies on reward and motivation. Although it is the activation of dopamine receptors that initiates the emission of 50-kHz USVs, non-dopaminergic mechanisms may modulate calling in the 50 kHz frequency band. To further elucidate these mechanisms, the present study investigated whether the pharmacological manipulation of glucocorticoid signaling influenced calling. Rats were administered corticosterone (1-5 mg/kg, s.c.), the glucocorticoid receptor antagonist mifepristone (40 or 100 mg/kg, s.c.), or the corticosterone synthesis inhibitor metyrapone (50 or 100 mg/kg, i.p.). The effects of these drugs on calling initiation and on calling recorded during nonaggressive social contacts or after the administration of amphetamine (0.25 or 1 mg/kg, i.p.) were then evaluated. Corticosterone failed to initiate the emission of 50-kHz USVs and did not influence pro-social and amphetamine-stimulated calling. Similarly, mifepristone and metyrapone did not initiate calling. However, metyrapone suppressed pro-social calling and calling stimulated by a moderate dose (1 mg/kg, i.p.) of amphetamine. Conversely, mifepristone attenuated calling stimulated by a low (0.25 mg/kg, i.p.), but not moderate (1 mg/kg, i.p.), dose of amphetamine and had no influence on pro-social calling. The present results demonstrate that glucocorticoid signaling modulates calling in the 50 kHz frequency band only in certain conditions and suggest that mechanisms different from the inhibition of corticosterone synthesis may participate in the suppression of calling by metyrapone. © The Author 2017. Published by Oxford University Press on behalf of CINP.

  3. Experimental simulation of satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds

    OpenAIRE

    Fullekrug, Martin; Hanuise, C; Parrot, M

    2011-01-01

    Relativistic electron beams above thunderclouds emit 100 kHz radio waves which illuminate the Earth's atmosphere and near-Earth space. This contribution aims to clarify the physical processes which are relevant for the spatial spreading of the radio wave energy below and above the ionosphere and thereby enables an experimental simulation of satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds. The simulation uses the DEMETER satellite which...

  4. arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays

    Directory of Open Access Journals (Sweden)

    Moreau Yves

    2005-05-01

    Full Text Available Abstract Background The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has triggered and accelerated the use of several platforms for analysis of DNA copy number changes, amongst others microarray comparative genomic hybridization (arrayCGH. One of the challenges inherent to this new technology is the management and analysis of large numbers of data points generated in each individual experiment. Results We have developed arrayCGHbase, a comprehensive analysis platform for arrayCGH experiments consisting of a MIAME (Minimal Information About a Microarray Experiment supportive database using MySQL underlying a data mining web tool, to store, analyze, interpret, compare, and visualize arrayCGH results in a uniform and user-friendly format. Following its flexible design, arrayCGHbase is compatible with all existing and forthcoming arrayCGH platforms. Data can be exported in a multitude of formats, including BED files to map copy number information on the genome using the Ensembl or UCSC genome browser. Conclusion ArrayCGHbase is a web based and platform independent arrayCGH data analysis tool, that allows users to access the analysis suite through the internet or a local intranet after installation on a private server. ArrayCGHbase is available at http://medgen.ugent.be/arrayCGHbase/.

  5. Development and validation of a 20K single nucleotide polymorphism (SNP) whole genome genotyping array for apple (Malus × domestica Borkh).

    Science.gov (United States)

    Bianco, Luca; Cestaro, Alessandro; Sargent, Daniel James; Banchi, Elisa; Derdak, Sophia; Di Guardo, Mario; Salvi, Silvio; Jansen, Johannes; Viola, Roberto; Gut, Ivo; Laurens, Francois; Chagné, David; Velasco, Riccardo; van de Weg, Eric; Troggio, Michela

    2014-01-01

    High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for screens of bi-parental populations. However, the number of robust and well-distributed markers contained on this array was not sufficient to perform genome-wide association analyses in wider germplasm sets, or Pedigree-Based Analysis at high precision, because of rapid decay of linkage disequilibrium. We describe the development of an Illumina Infinium array targeting 20K SNPs. The SNPs were predicted from re-sequencing data derived from the genomes of 13 Malus × domestica apple cultivars and one accession belonging to a crab apple species (M. micromalus). A pipeline for SNP selection was devised that avoided the pitfalls associated with the inclusion of paralogous sequence variants, supported the construction of robust multi-allelic SNP haploblocks and selected up to 11 entries within narrow genomic regions of ±5 kb, termed focal points (FPs). Broad genome coverage was attained by placing FPs at 1 cM intervals on a consensus genetic map, complementing them with FPs to enrich the ends of each of the chromosomes, and by bridging physical intervals greater than 400 Kbps. The selection also included ∼3.7K validated SNPs from the IRSC 8K array. The array has already been used in other studies where ∼15.8K SNP markers were mapped with an average of ∼6.8K SNPs per full-sib family. The newly developed array with its high density of polymorphic validated SNPs is expected to be of great utility for Pedigree-Based Analysis and Genomic Selection. It will also be a valuable tool to help dissect the genetic mechanisms controlling important fruit quality traits, and to aid the identification of marker-trait associations suitable for the application of Marker Assisted Selection in apple breeding programs.

  6. Development and validation of a 20K single nucleotide polymorphism (SNP whole genome genotyping array for apple (Malus × domestica Borkh.

    Directory of Open Access Journals (Sweden)

    Luca Bianco

    Full Text Available High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for screens of bi-parental populations. However, the number of robust and well-distributed markers contained on this array was not sufficient to perform genome-wide association analyses in wider germplasm sets, or Pedigree-Based Analysis at high precision, because of rapid decay of linkage disequilibrium. We describe the development of an Illumina Infinium array targeting 20K SNPs. The SNPs were predicted from re-sequencing data derived from the genomes of 13 Malus × domestica apple cultivars and one accession belonging to a crab apple species (M. micromalus. A pipeline for SNP selection was devised that avoided the pitfalls associated with the inclusion of paralogous sequence variants, supported the construction of robust multi-allelic SNP haploblocks and selected up to 11 entries within narrow genomic regions of ±5 kb, termed focal points (FPs. Broad genome coverage was attained by placing FPs at 1 cM intervals on a consensus genetic map, complementing them with FPs to enrich the ends of each of the chromosomes, and by bridging physical intervals greater than 400 Kbps. The selection also included ∼3.7K validated SNPs from the IRSC 8K array. The array has already been used in other studies where ∼15.8K SNP markers were mapped with an average of ∼6.8K SNPs per full-sib family. The newly developed array with its high density of polymorphic validated SNPs is expected to be of great utility for Pedigree-Based Analysis and Genomic Selection. It will also be a valuable tool to help dissect the genetic mechanisms controlling important fruit quality traits, and to aid the identification of marker-trait associations suitable for the application of Marker Assisted Selection in apple breeding programs.

  7. Development and Validation of a 20K Single Nucleotide Polymorphism (SNP) Whole Genome Genotyping Array for Apple (Malus × domestica Borkh)

    Science.gov (United States)

    Bianco, Luca; Cestaro, Alessandro; Sargent, Daniel James; Banchi, Elisa; Derdak, Sophia; Di Guardo, Mario; Salvi, Silvio; Jansen, Johannes; Viola, Roberto; Gut, Ivo; Laurens, Francois; Chagné, David; Velasco, Riccardo; van de Weg, Eric; Troggio, Michela

    2014-01-01

    High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for screens of bi-parental populations. However, the number of robust and well-distributed markers contained on this array was not sufficient to perform genome-wide association analyses in wider germplasm sets, or Pedigree-Based Analysis at high precision, because of rapid decay of linkage disequilibrium. We describe the development of an Illumina Infinium array targeting 20K SNPs. The SNPs were predicted from re-sequencing data derived from the genomes of 13 Malus × domestica apple cultivars and one accession belonging to a crab apple species (M. micromalus). A pipeline for SNP selection was devised that avoided the pitfalls associated with the inclusion of paralogous sequence variants, supported the construction of robust multi-allelic SNP haploblocks and selected up to 11 entries within narrow genomic regions of ±5 kb, termed focal points (FPs). Broad genome coverage was attained by placing FPs at 1 cM intervals on a consensus genetic map, complementing them with FPs to enrich the ends of each of the chromosomes, and by bridging physical intervals greater than 400 Kbps. The selection also included ∼3.7K validated SNPs from the IRSC 8K array. The array has already been used in other studies where ∼15.8K SNP markers were mapped with an average of ∼6.8K SNPs per full-sib family. The newly developed array with its high density of polymorphic validated SNPs is expected to be of great utility for Pedigree-Based Analysis and Genomic Selection. It will also be a valuable tool to help dissect the genetic mechanisms controlling important fruit quality traits, and to aid the identification of marker-trait associations suitable for the application of Marker Assisted Selection in apple breeding programs. PMID:25303088

  8. Seeded perturbations in wire array z-pinches

    International Nuclear Information System (INIS)

    Robinson, Allen Conrad; Kantsyrev, Victor Leonidovich; Wunsch, Scott Edward; Oliver, Bryan Velten; Lebedev, Sergey V.; Safronova, Alla S.; Maxwell, J.; McKenney, John Lee; Ampleford, David J.; Rapley, J.; Bott, S.C.; Palmer, J.B.A.; Bland, Simon Nicholas; Jones, Brent Manley; Chittenden, Jeremy Paul; Garasi, Christopher Joseph; Hall, Gareth Neville; Mehlhorn, Thomas Alan; Deeney, Christopher

    2004-01-01

    The impact of 3D structure on wire array z-pinch dynamics is a topic of current interest, and has been studied by the controlled seeding of wire perturbations. First, Al wires were etched at Sandia, creating 20% radial perturbations with variable axial wavelength. Observations of magnetic bubble formation in the etched regions during experiments on the MAGPIE accelerator are discussed and compared to 3D MHD modeling. Second, thin NaF coatings of 1 mm axial extent were deposited on Al wires and fielded on the Zebra accelerator. Little or no axial transport of the NaF spectroscopic dopant was observed in spatially resolved K-shell spectra, which places constraints on particle diffusivity in dense z-pinch plasmas. Finally, technology development for seeding perturbations is discussed

  9. Communicating global cardiovascular risk: are icon arrays better than numerical estimates in improving understanding, recall and perception of risk?

    Science.gov (United States)

    Ruiz, Jorge G; Andrade, Allen D; Garcia-Retamero, Rocio; Anam, Ramanakumar; Rodriguez, Remberto; Sharit, Joseph

    2013-12-01

    Experts recommend that adults have their global cardiovascular risk assessed. We investigated whether icon arrays increase understanding, recall, perception of CVR, and behavioral intent as compared with numerical information. Male outpatient veterans, at an intermediate to high cardiovascular risk participated in a randomized controlled trial of a computer tutorial presenting individualized risk. Message format was presented in 3 formats: percentages, frequencies, and frequencies with icon arrays. We assessed understanding immediately (T1) and recall at 20 min (T2) and 2 weeks (T3) after the intervention. We assessed perceptions of importance/seriousness, intent to adhere, and self-efficacy at T1. Self-reported adherence was assessed at T3. One-hundred and twenty male veterans participated. Age, education, race, health literacy and numeracy were comparable at baseline. There were no differences in understanding at T1 [p = .31] and recall at T3 [p = .10]. Accuracy was inferior with frequencies with icon arrays than percentages or frequencies at T2 [p ≤ .001]. There were no differences in perception of seriousness and importance for heart disease, behavioral intent, self-efficacy, actual adherence and satisfaction. Icon arrays may impair short-term recall of CVR. Icon arrays will not necessarily result in better understanding and recall of medical risk in all patients. Published by Elsevier Ireland Ltd.

  10. 256-pixel microcalorimeter array for high-resolution γ-ray spectroscopy of mixed-actinide materials

    Energy Technology Data Exchange (ETDEWEB)

    Winkler, R., E-mail: rwinkler@lanl.gov [Los Alamos National Laboratory, Los Alamos, NM (United States); Hoover, A.S.; Rabin, M.W. [Los Alamos National Laboratory, Los Alamos, NM (United States); Bennett, D.A.; Doriese, W.B.; Fowler, J.W.; Hays-Wehle, J.; Horansky, R.D.; Reintsema, C.D.; Schmidt, D.R.; Vale, L.R.; Ullom, J.N. [National Institute of Standards and Technology, Boulder, CO (United States)

    2015-01-11

    The application of cryogenic microcalorimeter detectors to γ-ray spectroscopy allows for measurements with unprecedented energy resolution. These detectors are ideally suited for γ-ray spectroscopy applications for which the measurement quality is limited by the spectral overlap of many closely spaced transitions using conventional detector technologies. The non-destructive analysis of mixed-isotope Pu materials is one such application where the precision can be potentially improved utilizing microcalorimeter detectors compared to current state-of-the-art high-purity Ge detectors (HPGe). The LANL-NIST γ-ray spectrometer, a 256-pixel microcalorimeter array based on transition-edge sensors (TESs), was recently commissioned and used to collect data on a variety of Pu isotopic standards to characterize the instrument performance. These measurements represent the first time the simultaneous readout of all 256 pixels for measurements of mixed-isotope Pu materials has been achieved. The LANL-NIST γ-ray spectrometer has demonstrated an average pixel resolution of 55 eV full-width-at-half-maximum at 100 keV, nearly an order of magnitude better than HPGe detectors. Some challenges of the analysis of many-channel ultra-high resolution data and the techniques used to produce quality spectra for isotopic analysis will be presented. The LANL-NIST γ-ray spectrometer has also demonstrated stable operation and obtained high resolution measurements at total array event rates beyond 1 kHz. For a total event rate of 1.25 kHz, approximately 5.6 cps/pixel, a 72.2 eV average FWHM for the 103 keV photopeak of {sup 153}Gd was achieved.

  11. Label-free silicon photonic biosensor system with integrated detector array

    Science.gov (United States)

    Yan, Rongjin; Mestas, Santano P.; Yuan, Guangwei; Safaisini, Rashid; Dandy, David S.

    2010-01-01

    An integrated, inexpensive, label-free photonic waveguide biosensor system with multi-analyte capability has been implemented on a silicon photonics integrated circuit from a commercial CMOS line and tested with nanofilms. The local evanescent array coupled (LEAC) biosensor is based on a new physical phenomenon that is fundamentally different from the mechanisms of other evanescent field sensors. Increased local refractive index at the waveguide’s upper surface due to the formation of a biological nanofilm causes local modulation of the evanescent field coupled into an array of photodetectors buried under the waveguide. The planar optical waveguide biosensor system exhibits sensitivity of 20%/nm photocurrent modulation in response to adsorbed bovine serum albumin (BSA) layers less than 3 nm thick. In addition to response to BSA, an experiment with patterned photoresist as well as beam propagation method simulations support the evanescent field shift principle. The sensing mechanism enables the integration of all optical and electronic components for a multi-analyte biosensor system on a chip. PMID:19606292

  12. Label-free silicon photonic biosensor system with integrated detector array.

    Science.gov (United States)

    Yan, Rongjin; Mestas, Santano P; Yuan, Guangwei; Safaisini, Rashid; Dandy, David S; Lear, Kevin L

    2009-08-07

    An integrated, inexpensive, label-free photonic waveguide biosensor system with multi-analyte capability has been implemented on a silicon photonics integrated circuit from a commercial CMOS line and tested with nanofilms. The local evanescent array coupled (LEAC) biosensor is based on a new physical phenomenon that is fundamentally different from the mechanisms of other evanescent field sensors. Increased local refractive index at the waveguide's upper surface due to the formation of a biological nanofilm causes local modulation of the evanescent field coupled into an array of photodetectors buried under the waveguide. The planar optical waveguide biosensor system exhibits sensitivity of 20%/nm photocurrent modulation in response to adsorbed bovine serum albumin (BSA) layers less than 3 nm thick. In addition to response to BSA, an experiment with patterned photoresist as well as beam propagation method simulations support the evanescent field shift principle. The sensing mechanism enables the integration of all optical and electronic components for a multi-analyte biosensor system on a chip.

  13. Electrowetting of liquid polymer on petal-mimetic microbowl-array surfaces for formation of microlens array with varying focus on a single substrate

    Science.gov (United States)

    Li, Xiangmeng; Shao, Jinyou; Li, Xiangming; Tian, Hongmiao

    2015-03-01

    In this paper, microlens array with varying focal lengths were fabricated on a single microbowl-array textured substrate. The solid microbowl-arrayed NOA61 (kind of polyurethane-based polymer with UV curablity) surface was resulted from nanoimprinting by polydimethylsiloxane (PDMS) mold. The PDMS mold was replicated from an SU-8 master which was generated by electron beam lithography. Such microbowl-arrayed surfaces demonstrate petal-mimetic highly adhesive hydrophobic wetting properties, which can promote an irreversible electrowetting (EW) effect and a dereased contact angle of water droplets as well as other liquid droplets by applying direct current (DC) voltage. To fabricate a microlens array with varying focal-lengths, liquid NOA61 was supplied from a syringe on the solid NOA61 microtextured film and DC voltage was applied succesively. After removing the DC voltage, these liquid NOA61 microdrops deposited on the solid microtextured NOA61 surface on tin-indium-oxide coated substrate could be solidified via UV irradiation, thus leading to microlens array with uneven numerical apertures on a single substrate. Numerical simulation was also done to verify the EW effect. Finally, optical imaging characterization was performed to confirm the varied focus of the NOA61 microdrops.

  14. The Applicability of Incoherent Array Processing to IMS Seismic Array Stations

    Science.gov (United States)

    Gibbons, S. J.

    2012-04-01

    The seismic arrays of the International Monitoring System for the CTBT differ greatly in size and geometry, with apertures ranging from below 1 km to over 60 km. Large and medium aperture arrays with large inter-site spacings complicate the detection and estimation of high frequency phases since signals are often incoherent between sensors. Many such phases, typically from events at regional distances, remain undetected since pipeline algorithms often consider only frequencies low enough to allow coherent array processing. High frequency phases that are detected are frequently attributed qualitatively incorrect backazimuth and slowness estimates and are consequently not associated with the correct event hypotheses. This can lead to missed events both due to a lack of contributing phase detections and by corruption of event hypotheses by spurious detections. Continuous spectral estimation can be used for phase detection and parameter estimation on the largest aperture arrays, with phase arrivals identified as local maxima on beams of transformed spectrograms. The estimation procedure in effect measures group velocity rather than phase velocity and the ability to estimate backazimuth and slowness requires that the spatial extent of the array is large enough to resolve time-delays between envelopes with a period of approximately 4 or 5 seconds. The NOA, AKASG, YKA, WRA, and KURK arrays have apertures in excess of 20 km and spectrogram beamforming on these stations provides high quality slowness estimates for regional phases without additional post-processing. Seven arrays with aperture between 10 and 20 km (MJAR, ESDC, ILAR, KSRS, CMAR, ASAR, and EKA) can provide robust parameter estimates subject to a smoothing of the resulting slowness grids, most effectively achieved by convolving the measured slowness grids with the array response function for a 4 or 5 second period signal. The MJAR array in Japan recorded high SNR Pn signals for both the 2006 and 2009 North Korea

  15. Wound healing with nonthermal microplasma jets generated in arrays of hourglass microcavity devices

    Science.gov (United States)

    Hum Park, Chan; Lee, Joong Seob; Heui Kim, Ji; Kim, Dong-Kyu; Lee, Ok Joo; Ju, Hyung Woo; Moon, Bo Mi; Cho, Jin Hoon; Kim, Min Hwan; Sun, Peter Peng; Park, Sung-Jin; Eden, J. Gary

    2014-10-01

    Clinical studies are reported in which artificial wounds in rat epidermal and dermal tissue have been treated by arrays of sub-500 µm diameter, low temperature plasma microjets. Fabricated in Al/nanoporous alumina (Al2O3) by wet chemical and microablation processes, each plasma jet device has a double parabolic (hourglass) structure, and arrays as large as 6  ×  6 devices with 500 µm diameter apertures have been tested to date. Treatment of 1 cm2 acute epidermal wounds for 20-40 s daily with an array of microplasma jets generated in He feedstock gas promoted wound recovery significantly, as evidenced by tissue histology and measured wound area. Seven days after wound formation, the wound area of the untreated control was 40  ±  2% of its initial value, whereas that for an identical wound treated twice daily for 20 s was 9  ±  2% of its original surface area. No histological distinctions were observed between wounds treated twice each day for 10 or 20 s - only the full recovery time differed. Spectra produced in the visible and ultraviolet by He jets in room air are dominated by atomic oxygen (3p 5P → 3s 5S) at 777 nm and violet fluorescence (391.4 nm) from N2+, a species produced when the He (2s 3S1) metastable is deactivated by Penning ionization of N2. Although the combined cross-sectional area of the jets in the array is only 7% of the wound area, the microplasma treatment results in spatially uniform, and accelerated, wound healing. Both effects are attributed to the increased surface area of the jet array (relative to a single jet having an equivalent diameter) and the concomitant enhancement in the generation of molecular radicals, and metastable atoms and molecules (such as {{\\text{N}}2}≤ft(A{}{}3 Σ \\text{u}+\\right) ).

  16. Wound healing with nonthermal microplasma jets generated in arrays of hourglass microcavity devices

    International Nuclear Information System (INIS)

    Park, Chan Hum; Lee, Joong Seob; Kim, Ji Heui; Kim, Dong-Kyu; Lee, Ok Joo; Ju, Hyung Woo; Moon, Bo Mi; Cho, Jin Hoon; Kim, Min Hwan; Sun, Peter Peng; Park, Sung-Jin; Eden, J Gary

    2014-01-01

    Clinical studies are reported in which artificial wounds in rat epidermal and dermal tissue have been treated by arrays of sub-500 µm diameter, low temperature plasma microjets. Fabricated in Al/nanoporous alumina (Al 2 O 3 ) by wet chemical and microablation processes, each plasma jet device has a double parabolic (hourglass) structure, and arrays as large as 6  ×  6 devices with 500 µm diameter apertures have been tested to date. Treatment of 1 cm 2 acute epidermal wounds for 20–40 s daily with an array of microplasma jets generated in He feedstock gas promoted wound recovery significantly, as evidenced by tissue histology and measured wound area. Seven days after wound formation, the wound area of the untreated control was 40  ±  2% of its initial value, whereas that for an identical wound treated twice daily for 20 s was 9  ±  2% of its original surface area. No histological distinctions were observed between wounds treated twice each day for 10 or 20 s – only the full recovery time differed. Spectra produced in the visible and ultraviolet by He jets in room air are dominated by atomic oxygen (3p 5 P → 3s 5 S) at 777 nm and violet fluorescence (391.4 nm) from N 2 + , a species produced when the He (2s 3 S 1 ) metastable is deactivated by Penning ionization of N 2 . Although the combined cross-sectional area of the jets in the array is only 7% of the wound area, the microplasma treatment results in spatially uniform, and accelerated, wound healing. Both effects are attributed to the increased surface area of the jet array (relative to a single jet having an equivalent diameter) and the concomitant enhancement in the generation of molecular radicals, and metastable atoms and molecules (such as N 2 (A 3 Σ u + )). (paper)

  17. A microfluidic chip with a U-shaped microstructure array for multicellular spheroid formation, culturing and analysis

    International Nuclear Information System (INIS)

    Fu, Chien-Yu; Chang, Hwan-You; Tseng, Sheng-Yang; Yang, Shih-Mo; Hsu, Long; Liu, Cheng-Hsien

    2014-01-01

    Multicellular spheroids (MCS), formed by self-assembly of single cells, are commonly used as a three-dimensional cell culture model to bridge the gap between in vitro monolayer culture and in vivo tissues. However, current methods for MCS generation and analysis still suffer drawbacks such as being labor-intensive and of poor controllability, and are not suitable for high-throughput applications. This study demonstrates a novel microfluidic chip to facilitate MCS formation, culturing and analysis. The chip contains an array of U-shaped microstructures fabricated by photopolymerizing the poly(ethylene glycol) diacrylate hydrogel through defining the ultraviolet light exposure pattern with a photomask. The geometry of the U-shaped microstructures allowed trapping cells into the pocket through the actions of fluid flow and the force of gravity. The hydrogel is non-adherent for cells, promoting the formation of MCS. Its permselective property also facilitates exchange of nutrients and waste for MCS, while providing protection of MCS from shearing stress during the medium perfusion. Heterotypic MCS can be formed easily by manipulating the cell trapping steps. Subsequent drug susceptibility analysis and long-term culture could also be achieved within the same chip. This MCS formation and culture platform can be used as a micro-scale bioreactor and applied in many cell biology and drug testing studies. (paper)

  18. OPTIMATION OF 48 KHZ ULTRASONIC WAVE DOSE FOR THE INACTIVATION OF SALMONELLA TYPHI

    Directory of Open Access Journals (Sweden)

    Dwi May Lestari

    2015-01-01

    Full Text Available This study was aimed to determine the effect of ultrasonic dose exposure which could decrease the viability of Salmonella typhi by using the variation of exposure time (15, 20, 25, and 30 minutes and volume of bacterial suspension (2, 4, 6, and 8 ml at constant power. The sample used was Salmonella typhi. Ultrasonic wave transmitter was a piezoelectric tweeter with 0,191 watts of power and 48 kHz frequency generated by the signal generator. Piezoelectric tweeter was a kind of transducer which converted electrical energy into ultrasonic energy. This research was an experimental laboratory with a completely randomized design. The decrease of bacterial percentage was calculated by using TPC (Total Plate Count. Data were analyzed by using One Way Anova. The results showed that the variation of exposure time and volume of bacterial suspension gave significant effect on the percentage of Salmonella typhi kill. The most optimal of ultrasonic dose exposure to kill Salmonella typhi was 281.87 J/ml with 100% bacterial kill.

  19. Analysis and modeling of low voltage electrical network at power line carrier frequencies (3-148.5 kHz); Analyse et modelisation du reseau basse tension aux frequences courants porteurs (3 KHZ-148,5 KHZ)

    Energy Technology Data Exchange (ETDEWEB)

    Duval, G.

    1998-07-01

    Electricite de France (EdF) wishes to establish a physical communication link between his clients and the EdF centres. The final link, i.e. between the high/low voltage transformation substation and the residential clients, being ensured by carrier currents. With this aim, an analysis and a modeling of the low voltage network at the carrier frequencies (3 kHz - 148.5 kHz) has been performed. This work has been carried out in parallel with an experiment involving 3500 apparatuses that use carrier currents. The diversity of the French low voltage networks and the limitations imposed by the EN50065-1 standard about the use of carrier currents in Europe do not favour the development of such carrier current systems. Disturbing voltages and localized impedances represent the main difficulties to get round. Inside accommodations, domotic carrier currents have a reduced range but a higher disturbance amplitude because of the proximity of appliances. A differential mode to common mode conversion phenomenon has been evidenced which generates network couplings and important electromagnetic fields. Energy lines and cables have been analyzed using numerical models. Load peaks have been analyzed using statistical tools in order to take into account the daily fluctuations. The modeling of the network is made in two steps: a double-wire model is considered first. Then a three-phase model is developed which analyzes the inter-phases coupling and the effect of the distribution of clients' loads on each phase. The results of this model are conformable with measurements except for underground networks. As perspectives of future works and beyond todays standard framework, the techniques that allow a sensible increase of communication flow rates have been reviewed. (J.S.)

  20. Lectin-Array Blotting.

    Science.gov (United States)

    Pazos, Raquel; Echevarria, Juan; Hernandez, Alvaro; Reichardt, Niels-Christian

    2017-09-01

    Aberrant protein glycosylation is a hallmark of cancer, infectious diseases, and autoimmune or neurodegenerative disorders. Unlocking the potential of glycans as disease markers will require rapid and unbiased glycoproteomics methods for glycan biomarker discovery. The present method is a facile and rapid protocol for qualitative analysis of protein glycosylation in complex biological mixtures. While traditional lectin arrays only provide an average signal for the glycans in the mixture, which is usually dominated by the most abundant proteins, our method provides individual lectin binding profiles for all proteins separated in the gel electrophoresis step. Proteins do not have to be excised from the gel for subsequent analysis via the lectin array but are transferred by contact diffusion from the gel to a glass slide presenting multiple copies of printed lectin arrays. Fluorescently marked glycoproteins are trapped by the printed lectins via specific carbohydrate-lectin interactions and after a washing step their binding profile with up to 20 lectin probes is analyzed with a fluorescent scanner. The method produces the equivalent of 20 lectin blots in a single experiment, giving detailed insight into the binding epitopes present in the fractionated proteins. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  1. Broadband 2D electronic spectrometer using white light and pulse shaping: noise and signal evaluation at 1 and 100 kHz.

    Science.gov (United States)

    Kearns, Nicholas M; Mehlenbacher, Randy D; Jones, Andrew C; Zanni, Martin T

    2017-04-03

    We have developed a broad bandwidth two-dimensional electronic spectrometer that operates shot-to-shot at repetition rates up to 100 kHz using an acousto-optic pulse shaper. It is called a two-dimensional white-light (2D-WL) spectrometer because the input is white-light supercontinuum. Methods for 100 kHz data collection are studied to understand how laser noise is incorporated into 2D spectra during measurement. At 100 kHz, shot-to-shot scanning of the delays and phases of the pulses in the pulse sequence produces a 2D spectrum 13-times faster and with the same signal-to-noise as using mechanical stages and a chopper. Comparing 100 to 1 kHz repetition rates, data acquisition time is decreased by a factor of 200, which is beyond the improvement expected by the repetition rates alone due to reduction in 1/f noise. These improvements arise because shot-to-shot readout and modulation of the pulse train at 100 kHz enables the electronic coherences to be measured faster than the decay in correlation between laser intensities. Using white light supercontinuum for the pump and probe pulses produces high signal-to-noise spectra on samples with optical densities 200 nm bandwidth.

  2. An Ultra-Wideband Millimeter-Wave Phased Array

    Science.gov (United States)

    Novak, Markus H.; Miranda, Felix A.; Volakis, John L.

    2016-01-01

    Wideband millimeter-wave arrays are of increasing importance due to their growing use in high data rate systems, including 5G communication networks. In this paper, we present a new class of ultra-wideband millimeter wave arrays that operate from nearly 20 GHz to 90 GHz. The array is based on tightly coupled dipoles. Feeding designs and fabrication challenges are presented, and a method for suppressing feed resonances is provided.

  3. Ordered arrays of nanoporous gold nanoparticles

    Directory of Open Access Journals (Sweden)

    Dong Wang

    2012-09-01

    Full Text Available A combination of a “top-down” approach (substrate-conformal imprint lithography and two “bottom-up” approaches (dewetting and dealloying enables fabrication of perfectly ordered 2-dimensional arrays of nanoporous gold nanoparticles. The dewetting of Au/Ag bilayers on the periodically prepatterned substrates leads to the interdiffusion of Au and Ag and the formation of an array of Au–Ag alloy nanoparticles. The array of alloy nanoparticles is transformed into an array of nanoporous gold nanoparticles by a following dealloying step. Large areas of this new type of material arrangement can be realized with this technique. In addition, this technique allows for the control of particle size, particle spacing, and ligament size (or pore size by varying the period of the structure, total metal layer thickness, and the thickness ratio of the as-deposited bilayers.

  4. Frequency-domain multiplexing of TES microcalorimeter array with CABBAGE

    International Nuclear Information System (INIS)

    Iyomoto, N.; Ichitsubo, T.; Mitsuda, K.; Yamasaki, N.Y.; Fujimoto, R.; Oshima, T.; Futamoto, K.; Takei, Y.; Fujimori, T.; Yoshida, K.; Ishisaki, Y.; Morita, U.; Koga, T.; Shinozaki, K.; Sato, K.; Takai, N.; Ohashi, T.; Miyazaki, T.; Nakayama, S.; Tanaka, K.; Morooka, T.; Chinone, K.

    2004-01-01

    Properties of Transition-Edge Sensor (TES) microcalorimeters operated with AC bias are studied utilizing the calorimeter Wheatstone bridge circuit called Calorimeter Bridge Biased by an AC Generator (CABBAGE). The CABBAGE eliminates the AC carrier significantly, thus enables us to study the AC responses of the TES with high sensitivity. We tested two kinds of TES devices operating at 110 and 440 mK, respectively. With the 110 mK device biased with 25 kHz, an energy resolution of 28 eV is obtained for Mn Kα line. On the other hand, we multiplexed the signals from two 440 mK device biased with 50 and 20 kHz, respectively, and obtained 167 and 271 eV energy resolutions. Even at the balance point of the bridge, AC signal did not disappear and odd-order harmonics were observed. They are considered to arise from the current dependence of the TES resistance, which is characterized by β≡d log R/d log I. Numerical solution for the CABBAGE response can reproduce the experimental results well if β=0.24±0.02. Since the harmonics may cause severe problem in the SQUID operation even after attenuated by a band-pass filter, especially at high bias frequency operation such as several hundred kHz, it is important to make β small

  5. Let's go formative: continuous student ratings with Web 2.0 application Twitter.

    Science.gov (United States)

    Stieger, Stefan; Burger, Christoph

    2010-04-01

    Student ratings have been a controversial but important method for the improvement of teaching quality during the past several decades. Most universities rely on summative evaluations conducted at the end of a term or course. A formative approach in which each course unit is evaluated may be beneficial for students and teachers but has rarely been applied. This is most probably due to the time constraints associated with various procedures inherent in formative evaluation (numerous evaluations, high amounts of aggregated data, high administrative investment). In order to circumvent these disadvantages, we chose the Web 2.0 Internet application Twitter as evaluation tool and tested whether it is useful for the implementation of a formative evaluation. After a first pilot and subsequent experimental study, the following conclusions were drawn: First, the formative evaluation did not come to the same results as the summative evaluation at the end of term, suggesting that formative evaluations tap into different aspects of course evaluation than summative evaluations do. Second, the results from an offline (i.e., paper-pencil) summative evaluation were identical with those from an online summative evaluation of the same course conducted a week later. Third, the formative evaluation did not influence the ratings of the summative evaluation at the end of the term. All in all, we can conclude that Twitter is a useful tool for evaluating a course formatively (i.e., on a weekly basis). Because of Twitter's simple use and the electronic handling of data, the administrative effort remains small.

  6. Far forward scattering on TOSCA tokamak using a detector array

    International Nuclear Information System (INIS)

    Cote, A.; Evans, D.E.

    1987-01-01

    A gaussian beam from a CW CO 2 , laser is directed across the vertical minor diameter of TOSCA tokamak where it undergoes collective scattering at angles within the beam divergence. Scattered radiation recombines with the unperturbed part of the beam on the detector, generating intensity oscillations whose spatial, temporal, and phase distributions convey information about the strength, scale length, frequency, and propagation direction of the plasma density fluctuations in which they originate. The distribution of these oscillations is measured across the diameter of the probe beam profile, either with a single photoconductive Ge:Hg detector over a sequence of plasma discharges, or with a 12-channel array of Ge:Hg detectors during a single discharge. A model describing counter-rotating waves, such as a poloidal structure encountered twice by the probe beam as it traverses the plasma, is able to furnish a satisfactory fit to the data. Use of the array provides a phase distribution from which the sense of rotation of the waves can be deduced. A dispersion relation with frequencies up to 250 kHz, wavenumbers in the range 60-300 m -1 , and a phase velocity of ≅ 6x10 3 ms -1 is found

  7. An integrated multiple capillary array electrophoresis system for high-throughput DNA sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Lu, X.

    1998-03-27

    A capillary array electrophoresis system was chosen to perform DNA sequencing because of several advantages such as rapid heat dissipation, multiplexing capabilities, gel matrix filling simplicity, and the mature nature of the associated manufacturing technologies. There are two major concerns for the multiple capillary systems. One concern is inter-capillary cross-talk, and the other concern is excitation and detection efficiency. Cross-talk is eliminated through proper optical coupling, good focusing and immersing capillary array into index matching fluid. A side-entry excitation scheme with orthogonal detection was established for large capillary array. Two 100 capillary array formats were used for DNA sequencing. One format is cylindrical capillary with 150 {micro}m o.d., 75 {micro}m i.d and the other format is square capillary with 300 {micro}m out edge and 75 {micro}m inner edge. This project is focused on the development of excitation and detection of DNA as well as performing DNA sequencing. The DNA injection schemes are discussed for the cases of single and bundled capillaries. An individual sampling device was designed. The base-calling was performed for a capillary from the capillary array with the accuracy of 98%.

  8. SOFT LAGS IN NEUTRON STAR kHz QUASI-PERIODIC OSCILLATIONS: EVIDENCE FOR REVERBERATION?

    Energy Technology Data Exchange (ETDEWEB)

    Barret, Didier, E-mail: didier.barret@irap.omp.eu [Universite de Toulouse, UPS-OMP, IRAP, F-31400 Toulouse (France); CNRS, Institut de Recherche en Astrophysique et Planetologie, 9 Av. colonel Roche, BP 44346, F-31028 Toulouse cedex 4 (France)

    2013-06-10

    High frequency soft reverberation lags have now been detected from stellar mass and supermassive black holes. Their interpretation involves reflection of a hard source of photons onto an accretion disk, producing a delayed reflected emission, with a time lag consistent with the light travel time between the irradiating source and the disk. Independently of the location of the clock, the kHz quasi-periodic oscillation (QPO) emission is thought to arise from the neutron star boundary layer. Here, we search for the signature of reverberation of the kHz QPO emission, by measuring the soft lags and the lag energy spectrum of the lower kHz QPOs from 4U1608-522. Soft lags, ranging from {approx}15 to {approx}40 {mu}s, between the 3-8 keV and 8-30 keV modulated emissions are detected between 565 and 890 Hz. The soft lags are not constant with frequency and show a smooth decrease between 680 Hz and 890 Hz. The broad band X-ray spectrum is modeled as the sum of a disk and a thermal Comptonized component, plus a broad iron line, expected from reflection. The spectral parameters follow a smooth relationship with the QPO frequency, in particular the fitted inner disk radius decreases steadily with frequency. Both the bump around the iron line in the lag energy spectrum and the consistency between the lag changes and the inferred changes of the inner disk radius, from either spectral fitting or the QPO frequency, suggest that the soft lags may indeed involve reverberation of the hard pulsating QPO source on the disk.

  9. Air-Coupled Low Frequency Ultrasonic Transducers and Arrays with PMN-32%PT Piezoelectric Crystals

    Directory of Open Access Journals (Sweden)

    Rymantas J. Kazys

    2017-01-01

    Full Text Available Air-coupled ultrasonic techniques are being increasingly used for material characterization, non-destructive evaluation of composite materials using guided waves as well as for distance measurements. Application of those techniques is mainly limited by the big losses of ultrasonic signals due to attenuation and mismatch of the acoustic impedances of ultrasonic transducers and air. One of the ways to solve this problem is by application of novel more efficient piezoelectric materials like lead magnesium niobate-lead titanate (PMN-PT type crystals. The objective of this research was the development and investigation of low frequency (<50 kHz wide band air-coupled ultrasonic transducers and arrays with an improved performance using PMN-32%PT crystals. Results of finite element modelling and experimental investigations of the developed transducers and arrays are presented. For improvement of the performance strip-like matching elements made of low acoustic impedance, materials such as polystyrene foams were applied. It allowed to achieve transduction losses for one single element transducer −11.4 dB, what is better than of commercially available air-coupled ultrasonic transducers. Theoretical and experimental investigations of the acoustic fields radiated by the eight element ultrasonic array demonstrated not only a good performance of the array in a pulse mode, but also very good possibilities to electronically focus and steer the ultrasonic beam in space.

  10. 3600 digital phase detector with 100-kHz bandwidth

    International Nuclear Information System (INIS)

    Reid, D.W.; Riggin, D.; Fazio, M.V.; Biddle, R.S.; Patton, R.D.; Jackson, H.A.

    1981-01-01

    The general availability of digital circuit components with propagation delay times of a few nanoseconds makes a digital phase detector with good bandwidth feasible. Such a circuit has a distinct advantage over its analog counterpart because of its linearity over wide range of phase shift. A phase detector that is being built at Los Alamos National Laboratory for the Fusion Materials Irradiation Test (FMIT) project is described. The specifications are 100-kHz bandwidth, linearity of +- 1 0 over +- 180 0 of phase shift, and 0.66 0 resolution. To date, the circuit has achieved the bandwidth and resolution. The linearity is approximately +- 3 0 over +- 180 0 phase shift

  11. Icon arrays help younger children's proportional reasoning.

    Science.gov (United States)

    Ruggeri, Azzurra; Vagharchakian, Laurianne; Xu, Fei

    2018-06-01

    We investigated the effects of two context variables, presentation format (icon arrays or numerical frequencies) and time limitation (limited or unlimited time), on the proportional reasoning abilities of children aged 7 and 10 years, as well as adults. Participants had to select, between two sets of tokens, the one that offered the highest likelihood of drawing a gold token, that is, the set of elements with the greater proportion of gold tokens. Results show that participants performed better in the unlimited time condition. Moreover, besides a general developmental improvement in accuracy, our results show that younger children performed better when proportions were presented as icon arrays, whereas older children and adults were similarly accurate in the two presentation format conditions. Statement of contribution What is already known on this subject? There is a developmental improvement in proportional reasoning accuracy. Icon arrays facilitate reasoning in adults with low numeracy. What does this study add? Participants were more accurate when they were given more time to make the proportional judgement. Younger children's proportional reasoning was more accurate when they were presented with icon arrays. Proportional reasoning abilities correlate with working memory, approximate number system, and subitizing skills. © 2018 The British Psychological Society.

  12. Spectroscopy of the hghest Rb2 bound states with 10 kHz precision

    NARCIS (Netherlands)

    Verhaar, B.J.; Kokkelmans, S.J.J.M.F.; van Kempen, E.G.M.; Freeland, R.S.; Wynar, R.; Comparat, D.; Ryu, C.; Heinzen, D.J.

    2001-01-01

    We have measured the binding energy of four of the highest bound vibrational levels of the ground electronic states of the ^87Rb2 molecule with a precision better than 10 kHz. The measurements were carried out using stimulated Raman photoassociation in an ^87Rb Bose-Einstein condensate. We have

  13. Post-Irradiation Examination of Array Targets - Part I

    Energy Technology Data Exchange (ETDEWEB)

    Icenhour, A.S.

    2004-01-23

    During FY 2001, two arrays, each containing seven neptunium-loaded targets, were irradiated at the Advanced Test Reactor in Idaho to examine the influence of multi-target self-shielding on {sup 236}Pu content and to evaluate fission product release data. One array consisted of seven targets that contained 10 vol% NpO{sub 2} pellets, while the other array consisted of seven targets that contained 20 vol % NpO{sub 2} pellets. The arrays were located in the same irradiation facility but were axially separated to minimize the influence of one array on the other. Each target also contained a dosimeter package, which consisted of a small NpO{sub 2} wire that was inside a vanadium container. After completion of irradiation and shipment back to the Oak Ridge National Laboratory, nine of the targets (four from the 10 vol% array and five from the 20 vol% array) were punctured for pressure measurement and measurement of {sup 85}Kr. These nine targets and the associated dosimeters were then chemically processed to measure the residual neptunium, total plutonium production, {sup 238}Pu production, and {sup 236}Pu concentration at discharge. The amount and isotopic composition of fission products were also measured. This report provides the results of the processing and analysis of the nine targets.

  14. All SiC Grid-Connected PV Supply with HF Link MPPT Converter: System Design Methodology and Development of a 20 kHz, 25 kVA Prototype

    Directory of Open Access Journals (Sweden)

    Serkan Öztürk

    2018-05-01

    Full Text Available Design methodology and implementation of an all SiC power semiconductor-based, grid-connected multi-string photovoltaic (PV supply with an isolated high frequency (HF link maximum power point tracker (MPPT have been described. This system configuration makes possible the use of a simple and reliable two-level voltage source inverter (VSI topology for grid connection, owing to the galvanic isolation provided by the HF transformer. This topology provides a viable alternative to the commonly used non-isolated PV supplies equipped with Si-based boost MPPT converters cascaded with relatively more complex inverter topologies, at competitive efficiency figures and a higher power density. A 20 kHz, 25 kVA prototype system was designed based on the dynamic model of the multi-string PV panels obtained from field tests. Design parameters such as input DC link capacitance, switching frequencies of MPPT converter and voltage source inverter, size and performance of HF transformer with nanocrystalline core, DC link voltage, and LCL filter of the VSI were optimized in view of the site dependent parameters such as the variation ranges of solar insolation, module surface temperature, and grid voltage. A modified synchronous reference frame control was implemented in the VSI by applying the grid voltage feedforward to the reference voltages in abc axes directly, so that zero-sequence components of grid voltages are taken into account in the case of an unbalanced grid. The system was implemented and the proposed design methodology verified satisfactorily in the field on a roof-mounted 23.7 kW multi-string PV system.

  15. Carbon nanotube array actuators

    International Nuclear Information System (INIS)

    Geier, S; Mahrholz, T; Wierach, P; Sinapius, M

    2013-01-01

    Experimental investigations of highly vertically aligned carbon nanotubes (CNTs), also known as CNT-arrays, are the main focus of this paper. The free strain as result of an active material behavior is analyzed via a novel experimental setup. Previous test experiences of papers made of randomly oriented CNTs, also called Bucky-papers, reveal comparably low free strain. The anisotropy of aligned CNTs promises better performance. Via synthesis techniques like chemical vapor deposition (CVD) or plasma enhanced CVD (PECVD), highly aligned arrays of multi-walled carbon nanotubes (MWCNTs) are synthesized. Two different types of CNT-arrays are analyzed, morphologically first, and optically tested for their active characteristics afterwards. One type of the analyzed arrays features tube lengths of 750–2000 μm with a large variety of diameters between 20 and 50 nm and a wave-like CNT-shape. The second type features a maximum, almost uniform, length of 12 μm and a constant diameter of 50 nm. Different CNT-lengths and array types are tested due to their active behavior. As result of the presented tests, it is reported that the quality of orientation is the most decisive property for excellent active behavior. Due to their alignment, CNT-arrays feature the opportunity to clarify the actuation mechanism of architectures made of CNTs. (paper)

  16. Engineering of highly ordered TiO2 nanopore arrays by anodization

    Science.gov (United States)

    Wang, Huijie; Huang, Zhennan; Zhang, Li; Ding, Jie; Ma, Zhaoxia; Liu, Yong; Kou, Shengzhong; Yang, Hangsheng

    2016-07-01

    Finite element analysis was used to simulate the current density distributions in the TiO2 barrier layer formed at the initial stage of Ti anodization. The morphology modification of the barrier layer was found to induce current density distribution change. By starting the anodization with proper TiO2 barrier layer morphology, the current density distribution can be adjusted to favor the formation of either nanotube arrays or nanopore arrays of anodic TiO2. We also found that the addition of sodium acetate into the electrolyte suppressed both the field-assisted chemical dissolution of TiO2 and the TiF62- hydrolysis induced TiO2 deposition during anodization, and thus further favored the nanopore formation. Accordingly, highly ordered anodic TiO2 nanopore arrays, similar to anodic aluminum oxide nanopore arrays, were successfully prepared.

  17. Stochastic synaptic plasticity with memristor crossbar arrays

    KAUST Repository

    Naous, Rawan

    2016-11-01

    Memristive devices have been shown to exhibit slow and stochastic resistive switching behavior under low-voltage, low-current operating conditions. Here we explore such mechanisms to emulate stochastic plasticity in memristor crossbar synapse arrays. Interfaced with integrate-and-fire spiking neurons, the memristive synapse arrays are capable of implementing stochastic forms of spike-timing dependent plasticity which parallel mean-rate models of stochastic learning with binary synapses. We present theory and experiments with spike-based stochastic learning in memristor crossbar arrays, including simplified modeling as well as detailed physical simulation of memristor stochastic resistive switching characteristics due to voltage and current induced filament formation and collapse. © 2016 IEEE.

  18. Stochastic synaptic plasticity with memristor crossbar arrays

    KAUST Repository

    Naous, Rawan; Al-Shedivat, Maruan; Neftci, Emre; Cauwenberghs, Gert; Salama, Khaled N.

    2016-01-01

    Memristive devices have been shown to exhibit slow and stochastic resistive switching behavior under low-voltage, low-current operating conditions. Here we explore such mechanisms to emulate stochastic plasticity in memristor crossbar synapse arrays. Interfaced with integrate-and-fire spiking neurons, the memristive synapse arrays are capable of implementing stochastic forms of spike-timing dependent plasticity which parallel mean-rate models of stochastic learning with binary synapses. We present theory and experiments with spike-based stochastic learning in memristor crossbar arrays, including simplified modeling as well as detailed physical simulation of memristor stochastic resistive switching characteristics due to voltage and current induced filament formation and collapse. © 2016 IEEE.

  19. Modulation of auroral electron fluxes in the frequency range 50 kHz to 10 MHz

    Science.gov (United States)

    Spiger, R. J.; Murphree, J. S.; Anderson, H. R.; Loewenstein, R. F.

    1976-01-01

    A sounding rocket-borne electron detector of high time resolution is used to search for modulation of auroral electron fluxes in the frequency range 50 kHz to 10 MHz and energy range 5-7 keV. Data were telemetered to ground via a 93-kHz subcarrier. A cross-correlation analysis of the data collected indicates low-level modulation near the detection threshold of the instrument. Two U-1 events are observed which are interpreted as indications of modulation. The two modulation events occur during a period of increasing flux for a region marking the boundary between two current sheets detected by the payload magnetometer. The strongest argument against interference contamination is the lack of any observable modulation at times other than those mentioned in the study.

  20. Ordered arrays of embedded Ga nanoparticles on patterned silicon substrates

    International Nuclear Information System (INIS)

    Bollani, M; Bietti, S; Sanguinetti, S; Frigeri, C; Chrastina, D; Reyes, K; Smereka, P; Millunchick, J M; Vanacore, G M; Tagliaferri, A; Burghammer, M

    2014-01-01

    We fabricate site-controlled, ordered arrays of embedded Ga nanoparticles on Si, using a combination of substrate patterning and molecular-beam epitaxial growth. The fabrication process consists of two steps. Ga droplets are initially nucleated in an ordered array of inverted pyramidal pits, and then partially crystallized by exposure to an As flux, which promotes the formation of a GaAs shell that seals the Ga nanoparticle within two semiconductor layers. The nanoparticle formation process has been investigated through a combination of extensive chemical and structural characterization and theoretical kinetic Monte Carlo simulations. (papers)

  1. Poor sensitization of 50-kHz vocalization response to amphetamine predicts rat susceptibility to self-administration of the drug

    OpenAIRE

    Taracha, Ewa; Kaniuga, Ewelina; Wyszogrodzka, Edyta; P?a?nik, Adam; Stefa?ski, Roman; Chrapusta, Stanis?aw J.

    2016-01-01

    Rationale Our previous studies showed promise for using sensitization of the frequency-modulated 50-kHz vocalization response to amphetamine (AMPH) as an index of rat vulnerability to AMPH addiction. Objective This study aimed to test the utility of sensitizing frequency-modulated (FM) 50-kHz vocalization in the AMPH self-administration paradigm as well as the ability of N-acetylcysteine to prevent self-administration relapse. Methods Rats were subjected to the so-called two-injection protoco...

  2. Backshort-Under-Grid arrays for infrared astronomy

    Science.gov (United States)

    Allen, C. A.; Benford, D. J.; Chervenak, J. A.; Chuss, D. T.; Miller, T. M.; Moseley, S. H.; Staguhn, J. G.; Wollack, E. J.

    2006-04-01

    We are developing a kilopixel, filled bolometer array for space infrared astronomy. The array consists of three individual components, to be merged into a single, working unit; (1) a transition edge sensor bolometer array, operating in the milliKelvin regime, (2) a quarter-wave backshort grid, and (3) superconducting quantum interference device multiplexer readout. The detector array is designed as a filled, square grid of suspended, silicon bolometers with superconducting sensors. The backshort arrays are fabricated separately and will be positioned in the cavities created behind each detector during fabrication. The grids have a unique interlocking feature machined into the walls for positioning and mechanical stability. The spacing of the backshort beneath the detector grid can be set from ˜30 300 μm, by independently adjusting two process parameters during fabrication. The ultimate goal is to develop a large-format array architecture with background-limited sensitivity, suitable for a wide range of wavelengths and applications, to be directly bump bonded to a multiplexer circuit. We have produced prototype two-dimensional arrays having 8×8 detector elements. We present detector design, fabrication overview, and assembly technologies.

  3. Dynamic array generation and pattern formation for optical tweezers

    DEFF Research Database (Denmark)

    Mogensen, P.C.; Glückstad, J.

    2000-01-01

    The generalised phase contrast approach is used for the generation of optical arrays of arbitrary beam shape, suitable for applications in optical tweezers for the manipulation of biological specimens. This approach offers numerous advantages over current techniques involving the use of computer......-generated holograms or diffractive optical elements. We demonstrate a low-loss system for generating intensity patterns suitable for the trapping and manipulation of small particles or specimens....

  4. A general melt-injection-decomposition route to oriented metal oxide nanowire arrays

    Science.gov (United States)

    Han, Dongqiang; Zhang, Xinwei; Hua, Zhenghe; Yang, Shaoguang

    2016-12-01

    In this manuscript, a general melt-injection-decomposition (MID) route has been proposed and realized for the fabrication of oriented metal oxide nanowire arrays. Nitrate was used as the starting materials, which was injected into the nanopores of the anodic aluminum oxide (AAO) membrane through the capillarity action in its liquid state. At higher temperature, the nitrate decomposed into corresponding metal oxide within the nanopores of the AAO membrane. Oriented metal oxide nanowire arrays were formed within the AAO membrane as a result of the confinement of the nanopores. Four kinds of metal oxide (CuO, Mn2O3, Co3O4 and Cr2O3) nanowire arrays are presented here as examples fabricated by this newly developed process. X-ray diffraction, scanning electron microscopy and transmission electron microscopy studies showed clear evidence of the formations of the oriented metal oxide nanowire arrays. Formation mechanism of the metal oxide nanowire arrays is discussed based on the Thermogravimetry and Differential Thermal Analysis measurement results.

  5. Characterization of TES bolometers used in 2-dimensional Backshort-Under-Grid (BUG) arrays for far-infrared astronomy

    International Nuclear Information System (INIS)

    Staguhn, J.G.; Allen, C.A.; Benford, D.J.; Chervenak, J.A.; Chuss, D.T.; Miller, T.M.; Moseley, S.H.; Wollack, E.J.

    2006-01-01

    We have produced a laboratory demonstration of our new Backshort-Under-Grid (BUG) bolometer array architecture in a monolithic, 2-dimensional, 8x8 format. The detector array is designed as a square grid of suspended, 1μm thick silicon bolometers with superconducting molybdium/gold bilayer TESs. These detectors use an additional layer of gold bars deposited on top of the bilayer, oriented transverse to the direction of the current flow, for the suppression of excess noise. This detector design has earlier been shown to provide near fundamental noise limited device performance. We present results from performance measurements of witness devices. In particular we demonstrate that the inband excess noise level of the TES detectors is less than 20% above the thermodynamic phonon noise limit and not significantly higher out of band at frequencies that cannot be attenuated by the Nyquist filter. Our 8x8 BUG arrays will be used in the near future for astronomical observations in several (sub-)millimeter instruments

  6. Low Frequency Phased Array Application for Crack Detection in Cast Austenitic Piping

    International Nuclear Information System (INIS)

    Anderson, Michael T.; Cumblidge, Stephen E.; Doctor, Steven R.

    2006-01-01

    As part of a multi-year program funded by the United States Nuclear Regulatory Commission (US NRC) to address nondestructive examination (NDE) reliability of inservice inspection (ISI) programs, studies conducted at the Pacific Northwest National Laboratory (PNNL) in Richland, Washington, have focused on assessing novel NDE approaches for the inspection of coarse-grained, cast stainless steel reactor components. The primary objective of this work is to provide information to the US NRC on the utility, effectiveness and reliability of ultrasonic testing (UT) as related to the ISI of primary piping components in US commercial nuclear power plants. This paper describes progress, recent developments and results from an assessment of a portion of the work relating to the ultrasonic low frequency phased array inspection technique. Westinghouse Owner's Group (WOG) cast stainless steel pipe segments with thermal and mechanical fatigue cracks, PNNL samples containing thermal fatigue cracks and several blank vintage specimens having very coarse grains that are representative of early centrifugally cast piping installed in PWRs, were used for assessing the inspection method. The phased array approach was implemented using an R/D Tech Tomoscan III system operating at 1.0 MHz and 500 kHz, providing composite volumetric images of the samples. Several dual, transmit-receive, custom designed low-frequency arrays were employed in laboratory trials. Results from laboratory studies for assessing detection, localization and length sizing effectiveness are discussed.

  7. Auditory stream formation affects comodulation masking release retroactively

    DEFF Research Database (Denmark)

    Dau, Torsten; Ewert, Stephan; Oxenham, A. J.

    2009-01-01

    . Detection thresholds for a 1-kHz sinusoidal signal were measured in the presence of a narrowband (20-Hz-wide) on-frequency masker with or without four comodulated or independent flanking bands that were spaced apart by either 1/6 (narrow spacing) or 1 octave (wide spacing). As expected, CMR was observed...

  8. Kerr hysteresis loop tracer with alternate driving magnetic field up to 10 kHz

    Science.gov (United States)

    Callegaro, Luca; Fiorini, Carlo; Triggiani, Giacomo; Puppin, Ezio

    1997-07-01

    A magneto-optical Kerr loop tracer for hysteresis loop measurements in thin films with field excitation frequency f0 from 10 mHz to 10 kHz is described. A very high sensitivity is obtained by using an ultrabright light-emitting diode as a low-noise light source and a novel acquisition process. The field is generated with a coil driven by an audio amplifier connected to a free-running oscillator. The conditioned detector output constitutes the magnetization signal (M); the magnetic field (H) is measured with a fast Hall probe. The acquisition electronics are based on a set of sample-and-hold amplifiers which allow the simultaneous sampling of M, H, and dH/dt. Acquisition is driven by a personal computer equipped with a multifunction I/O board. Test results on a 120 nm Fe film on Si substrate are shown. The coercive field of the film increases with frequency and nearly doubles at 10 kHz with respect to dc.

  9. Ultradense, Deep Subwavelength Nanowire Array Photovoltaics As Engineered Optical Thin Films

    KAUST Repository

    Tham, Douglas; Heath, James R.

    2010-01-01

    A photovoltaic device comprised of an array of 20 nm wide, 32 nm pitch array of silicon nanowires is modeled as an optical material. The nanowire array (NWA) has characteristic device features that are deep in the subwavelength regime for light

  10. Optimal array factor radiation pattern synthesis for linear antenna array using cat swarm optimization: validation by an electromagnetic simulator

    Institute of Scientific and Technical Information of China (English)

    Gopi RAM; Durbadal MANDAL; Sakti Prasad GHOSHAL; Rajib KAR

    2017-01-01

    In this paper, an optimal design of linear antenna arrays having microstrip patch antenna elements has been carried out. Cat swarm optimization (CSO) has been applied for the optimization of the control parameters of radiation pattern of an antenna array. The optimal radiation patterns of isotropic antenna elements are obtained by optimizing the current excitation weight of each element and the inter-element spacing. The antenna arrays of 12, 16, and 20 elements are taken as examples. The arrays are de-signed by using MATLAB computation and are validated through Computer Simulation Technology-Microwave Studio (CST-MWS). From the simulation results it is evident that CSO is able to yield the optimal design of linear antenna arrays of patch antenna elements.

  11. Phased laser diode array permits selective excitation of ultrasonic guided waves in coated bone-mimicking tubes

    Science.gov (United States)

    Moilanen, Petro; Salmi, Ari; Kilappa, Vantte; Zhao, Zuomin; Timonen, Jussi; Hæggström, Edward

    2017-10-01

    This paper validates simulation predictions, which state that specific modes could be enhanced in quantitative ultrasonic bone testing. Tunable selection of ultrasonic guided wave excitation is useful in non-destructive testing since it permits the mediation of energy into diagnostically useful modes while reducing the energy mediated into disturbing contributions. For instance, it is often challenging to distinguish and extract the useful modes from ultrasound signals measured in bone covered by a soft tissue. We show that a laser diode array can selectively excite ultrasound in bone mimicking phantoms. A fiber-coupled diode array (4 elements) illuminated two solid tubes (2-3 mm wall thickness) embraced by an opaque soft-tissue mimicking elastomer coating (5 mm thick). A predetermined time delay matching the selected mode and frequency was employed between the outputs of the elements. The generated ultrasound was detected by a 215 kHz piezo receiver. Our results suggest that this array reduces the disturbances caused by the elastomer cover and so pave way to permit non-contacting in vivo guided wave ultrasound assessment of human bones. The implementation is small, inexpensive, and robust in comparison with the conventional pulsed lasers.

  12. Biomimetic hydrogels for biosensor implant biocompatibility: electrochemical characterization using micro-disc electrode arrays (MDEAs).

    Science.gov (United States)

    Justin, Gusphyl; Finley, Stephen; Abdur Rahman, Abdur Rub; Guiseppi-Elie, Anthony

    2009-02-01

    Our interest is in the development of engineered microdevices for continuous remote monitoring of intramuscular lactate, glucose, pH and temperature during post-traumatic hemorrhaging. Two important design considerations in the development of such devices for in vivo diagnostics are discussed; the utility of micro-disc electrode arrays (MDEAs) for electrochemical biosensing and the application of biomimetic, bioactive poly(HEMA)-based hydrogel composites for implant biocompatibility. A poly(HEMA)-based hydrogel membrane containing polyethylene glycol (PEG) was UV cross-linked with tetraethyleneglycol diacrylate following application to MDEAs (50 mum discs) and to 250 mum diameter gold electrodes within 8-well culture ware. Cyclic voltammetry (CV) of the MDEAs revealed a reduction in the apparent diffusion coefficient of ferrocenemonocarboxylic acid (FcCO(2)H), from 6.68 x 10(-5) to 6.74 x 10(-6) cm(2)/s for the uncoated and 6 mum thick hydrogel coated devices, respectively. Single frequency (4 kHz) temporal impedance measurements of the hydrogels in the 8-well culture ware showed a reversible 5% change in the absolute impedance of the hydrogels when exposed to a pH change between 6.1 to 7.2 and a 20% drop between pH 6.1 and 8.8.

  13. Development of FIR arrays with integrating amplifiers

    Science.gov (United States)

    Young, Erick T.

    1988-08-01

    The development of optimized photoconductor arrays suitable for far infrared space astronomical applications are described. Although the primary impetus is the production of a 16 by 16 element Ge:Ga demonstration array for SIRTF, the extension of this technology to Large Deployable Reflector (LDR) is considered. The optimization of Ge:Ga and Ge:Be photoconductor materials is discussed. In collaboration with Lawrence Berkeley Laboratory, measurements of FIR photoconductors with quantum efficiencies greater than 20 percent at 100 micrometers, and dark currents below 300 electrons/s are presented. Integrating J-FET amplifier technology is discussed. The current generation of integrating amplifiers has a demonstrated read noise of less than 20 electrons for an integration time of 100 s. The design is shown for a stackable 16 x n Ge:Ga array that utilizes a 16-channel monolithic version of the J-FET integrator. A part of the design is the use of a thin, thermally insulating substrate that allows the electronics to operate at the optimum temperature of 50 K while maintaining thermal and optical isolation from the detectors at 2 K. The power dissipation for the array is less than 16 mW. The array design may particularly be applicable to high resolution imaging spectrometers for LDR.

  14. Anodic Fabrication of Ti-Ni-O Nanotube Arrays on Shape Memory Alloy

    Directory of Open Access Journals (Sweden)

    Qiang Liu

    2014-04-01

    Full Text Available Surface modification with oxide nanostructures is one of the efficient ways to improve physical or biomedical properties of shape memory alloys. This work reports a fabrication of highly ordered Ti-Ni-O nanotube arrays on Ti-Ni alloy substrates through pulse anodization in glycerol-based electrolytes. The effects of anodization parameters and the annealing process on the microstructures and surface morphology of Ti-Ni-O were studied using scanning electron microscope and Raman spectroscopy. The electrolyte type greatly affected the formation of nanotube arrays. A formation of anatase phase was found with the Ti-Ni-O nanotube arrays annealed at 450 °C. The oxide nanotubes could be crystallized to rutile phase after annealing treatment at 650 °C. The Ti-Ni-O nanotube arrays demonstrated an excellent thermal stability by keeping their nanotubular structures up to 650 °C.

  15. Thermoelastic expansion vs. piezoelectricity for high-frequency, 2-D arrays.

    Science.gov (United States)

    Buma, Takashi; Spisar, Monica; O'Donnell, Matthew

    2003-08-01

    Optical generation using the thermoelastic effect has traditionally suffered from low conversion efficiency. We previously demonstrated increased efficiency of nearly 20 dB with an optical absorbing layer consisting of a mixture of polydimethylsiloxane (PDMS) and carbon black spin coated onto a glass microscope slide. In this paper we show that the radiated power from a black PDMS film is comparable to a 20 MHz piezoelectric two-dimensional (2-D) array element. Furthermore, we predict that a thermoelastic array element can produce similar acoustic power levels compared to ideal piezoelectric 2-D array elements at frequencies in the 100 MHz regime. We believe these results show that thermoelastic generation of ultrasound is a promising alternative to piezoelectricity for high-frequency, 2-D arrays.

  16. Alcohol enhances unprovoked 22–28 kHz USVs and suppresses USV mean frequency in High Alcohol Drinking (HAD-1) male rats

    Science.gov (United States)

    Thakore, Neha; Reno, James M.; Gonzales, Rueben A.; Schallert, Timothy; Bell, Richard L.; Maddox, W. Todd; Duvauchelle, Christine L.

    2016-01-01

    Heightened emotional states increase impulsive behaviors such as excessive ethanol consumption in humans. Though positive and negative affective states in rodents can be monitored in real-time through ultrasonic vocalization (USV) emissions, few animal studies have focused on the role of emotional status as a stimulus for initial ethanol drinking. Our laboratory has recently developed reliable, high-speed analysis techniques to compile USV data during multiple-hour drinking sessions. Since High Alcohol Drinking (HAD-1) rats are selectively bred to voluntarily consume intoxicating levels of alcohol, we hypothesized that USVs emitted by HAD-1 rats would reveal unique emotional phenotypes predictive of alcohol intake and sensitive to alcohol experience. In this study, male HAD-1 rats had access to water, 15% and 30% EtOH or water only (i.e., Controls) during 8 weeks of daily 7-hr drinking-in-the-dark (DID) sessions. USVs, associated with both positive (i.e., 50–55 kHz frequency-modulated or FM) and negative (i.e., 22–28 kHz) emotional states, emitted during these daily DID sessions were examined. Findings showed basal 22–28 kHz USVs were emitted by both EtOH-Naïve (Control) and EtOH-experienced rats, alcohol experience enhanced 22–28 kHz USV emissions, and USV acoustic parameters (i.e., mean frequency in kHz) of both positive and negative USVs were significantly suppressed by chronic alcohol experience. These data suggest that negative affective status initiates and maintains excessive alcohol intake in selectively bred HAD-1 rats and support the notion that unprovoked emissions of negative affect-associated USVs (i.e., 22–28 kHz) predict vulnerability to excessive alcohol intake in distinct rodent models. PMID:26802730

  17. Borehole Array Observations of Non-Volcanic Tremor at SAFOD

    Science.gov (United States)

    Ellsworth, W. L.; Luetgert, J. H.; Oppenheimer, D. H.

    2005-12-01

    We report on the observation of non-volcanic tremor made in the San Andreas Fault Observatory at Depth in May, 2005 during the deployment of a multi-level borehole seismic array in the SAFOD main hole. The seismic array consisted of 80 levels of hydraulically-clamped 3-component, 15 Hz omni-directional geophones spaced 15.24 m apart along a 1200 m section of the inclined borehole between 1538 and 2363 m below the ground surface. The array was provided by Paulsson Geophysical Services, Inc. (P/GSI), and recorded at a sample rate of 4000 sps on 24-bit Geode digital recorders provided by Geometrics, Inc. More than 2 TB of continuous data were recorded during the 2-week deployment. Selected local earthquakes and explosions recorded by the array are available at the Northern California Earthquake Data Center, and the entire unedited data set is available as assembled data at the IRIS Data Management Center. Both data sets are currently in the industry standard SEG2 format. Episodes of non-volcanic tremor are common along this reach of the San Andreas Fault according to Nadeau and Dolenc [2004, DOI: 10.1126/science.1107142], with many originating about 30 km southeast of SAFOD beneath the southern end of the Parkfield segment and northern end of the Simmler segment of the fault. We identified tremor episodes using spectrograms routinely produced by the Northern California Seismic Network (http://quake.usgs.gov/cgi-bin/sgrampark.pl) on which they appear as periods of elevated noise relative to the background. A particularly strong tremor episode occurred on May 10, 2005 between 19:39 and 20:00 UTC. In SAFOD, tremor spectral levels exceed the instrumental noise floor to at least 40 Hz. The spatially unaliased recording of the tremor wavefield on the P/GSI array reveal individual phases that can be tracked continuously across the array. The wavefield is composed of both up- and down-going shear waves that form quasi-stationary interference patterns in which areas of

  18. Customizable PCR-microplate array for differential identification of multiple pathogens.

    Science.gov (United States)

    Woubit, Abdela; Yehualaeshet, Teshome; Roberts, Sherrelle; Graham, Martha; Kim, Moonil; Samuel, Temesgen

    2013-11-01

    Customizable PCR-microplate arrays were developed for the rapid identification of Salmonella Typhimurium, Salmonella Saintpaul, Salmonella Typhi, Shigella dysenteriae, Escherichia coli O157:H7, Francisella tularensis subsp. tularensis, Francisella tularensis subsp. novicida, Vibrio cholerae, Vibrio parahaemolyticus, Yersinia pestis, and Yersinia pseudotuberculosis. Previously, we identified highly specific primers targeting each of these pathogens. Here, we report the development of customizable PCR-microplate arrays for simultaneous identification of the pathogens using the primers identified. A mixed aliquot of genomic DNA from 38 strains was used to validate three PCR-microplate array formats. Identical PCR conditions were used to run all the samples on the three formats. Specific amplifications were obtained on all three custom plates. In preliminary tests performed to evaluate the sensitivity of these assays in samples inoculated in the laboratory with Salmonella Typhimurium, amplifications were obtained from 1 g of beef hot dog inoculated at as low as 9 CFU/ml or from milk inoculated at as low as 78 CFU/ml. Such microplate arrays could be valuable tools for initial identification or secondary confirmation of contamination by these pathogens.

  19. A Multi-Functional Microelectrode Array Featuring 59760 Electrodes, 2048 Electrophysiology Channels, Stimulation, Impedance Measurement and Neurotransmitter Detection Channels.

    Science.gov (United States)

    Dragas, Jelena; Viswam, Vijay; Shadmani, Amir; Chen, Yihui; Bounik, Raziyeh; Stettler, Alexander; Radivojevic, Milos; Geissler, Sydney; Obien, Marie; Müller, Jan; Hierlemann, Andreas

    2017-06-01

    Biological cells are characterized by highly complex phenomena and processes that are, to a great extent, interdependent. To gain detailed insights, devices designed to study cellular phenomena need to enable tracking and manipulation of multiple cell parameters in parallel; they have to provide high signal quality and high spatiotemporal resolution. To this end, we have developed a CMOS-based microelectrode array system that integrates six measurement and stimulation functions, the largest number to date. Moreover, the system features the largest active electrode array area to date (4.48×2.43 mm 2 ) to accommodate 59,760 electrodes, while its power consumption, noise characteristics, and spatial resolution (13.5 μm electrode pitch) are comparable to the best state-of-the-art devices. The system includes: 2,048 action-potential (AP, bandwidth: 300 Hz to 10 kHz) recording units, 32 local-field-potential (LFP, bandwidth: 1 Hz to 300 Hz) recording units, 32 current recording units, 32 impedance measurement units, and 28 neurotransmitter detection units, in addition to the 16 dual-mode voltage-only or current/voltage-controlled stimulation units. The electrode array architecture is based on a switch matrix, which allows for connecting any measurement/stimulation unit to any electrode in the array and for performing different measurement/stimulation functions in parallel.

  20. Self-assembled ordered carbon-nanotube arrays and membranes.

    Energy Technology Data Exchange (ETDEWEB)

    Overmyer, Donald L.; Siegal, Michael P.; Yelton, William Graham

    2004-11-01

    Imagine free-standing flexible membranes with highly-aligned arrays of carbon nanotubes (CNTs) running through their thickness. Perhaps with both ends of the CNTs open for highly controlled nanofiltration? Or CNTs at heights uniformly above a polymer membrane for a flexible array of nanoelectrodes or field-emitters? How about CNT films with incredible amounts of accessible surface area for analyte adsorption? These self-assembled crystalline nanotubes consist of multiple layers of graphene sheets rolled into concentric cylinders. Tube diameters (3-300 nm), inner-bore diameters (2-15 nm), and lengths (nanometers - microns) are controlled to tailor physical, mechanical, and chemical properties. We proposed to explore growth and characterize nanotube arrays to help determine their exciting functionality for Sandia applications. Thermal chemical vapor deposition growth in a furnace nucleates from a metal catalyst. Ordered arrays grow using templates from self-assembled hexagonal arrays of nanopores in anodized-aluminum oxide. Polymeric-binders can mechanically hold the CNTs in place for polishing, lift-off, and membrane formation. The stiffness, electrical and thermal conductivities of CNTs make them ideally suited for a wide-variety of possible applications. Large-area, highly-accessible gas-adsorbing carbon surfaces, superb cold-cathode field-emission, and unique nanoscale geometries can lead to advanced microsensors using analyte adsorption, arrays of functionalized nanoelectrodes for enhanced electrochemical detection of biological/explosive compounds, or mass-ionizers for gas-phase detection. Materials studies involving membrane formation may lead to exciting breakthroughs in nanofiltration/nanochromatography for the separation of chemical and biological agents. With controlled nanofilter sizes, ultrafiltration will be viable to separate and preconcentrate viruses and many strains of bacteria for 'down-stream' analysis.

  1. Determination of flavonoids in plant material by HPLC with diode-array and electro-array detections.

    Science.gov (United States)

    Mattila, P; Astola, J; Kumpulainen, J

    2000-12-01

    A high-performance liquid chromatographic (HPLC) method with in-line connected diode-array (DAD) and electro-array (EC) detection to identify and quantify 17 flavonoids in plant-derived foods is described. Catechins were extracted from the samples using ethyl acetate, and quantification of these compounds was performed with the EC detector. Other flavonoids were quantified with DAD after acid hydrolysis. The methods developed were effective for the determination of catechins and other flavonoids in plant-derived foods. Responses of the detection systems were linear within the range evaluated, 20-200 ng/injection (DAD) and 20-100 ng/injection (EC), with correlation coefficients exceeding 0.999. Coefficient of variation was under 10.5%, and recoveries of flavonoids ranged from 70 to 124%. Purity of the flavonoid peaks was confirmed by combining the spectral and voltammetric data.

  2. Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2.

    Science.gov (United States)

    Cai, Xiaoqiang; Nomura-Kitabayashi, Aya; Cai, Weibin; Yan, Jianyun; Christoffels, Vincent M; Cai, Chen-Leng

    2011-12-15

    During early embryogenesis, the formation of the cardiac atrioventricular canal (AVC) facilitates the transition of the heart from a linear tube into a chambered organ. However, the genetic pathways underlying this developmental process are poorly understood. The T-box transcription factor Tbx20 is expressed predominantly in the AVC of early heart tube. It was shown that Tbx20 activates Nmyc1 and suppresses Tbx2 expression to promote proliferation and specification of the atrial and ventricular chambers, yet it is not known if Tbx20 is involved in early AVC development. Here, we report that mice lacking Tbx20 in the AVC myocardium fail to form the AVC constriction, and the endocardial epithelial-mesenchymal transition (EMT) is severely perturbed. Tbx20 maintains expression of a variety of genes, including Bmp2, Tbx3 and Hand1 in the AVC myocardium. Intriguingly, we found Bmp2 downstream genes involved in the EMT initiation are also downregulated. In addition, re-expression of Bmp2 in the AVC myocardium substantially rescues the EMT defects resulting from the lack of Tbx20, suggesting Bmp2 is one of the key downstream targets of Tbx20 in AVC development. Our data support a complex signaling network with Tbx20 suppressing Tbx2 in the AVC myocardium but also indirectly promoting Tbx2 expression through Bmp2. The spatiotemporal expression of Tbx2 in the AVC appears to be balanced between these two opposing signals. Overall, our study provides genetic evidence that Tbx20 has essential roles in regulating AVC development that coordinate early cardiac chamber formation. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Structural anomalies induced by the metal deposition methods in 2D silver nanoparticle arrays prepared by nanosphere lithography

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Shengli, E-mail: huangsl@xmu.edu.cn [Fujian Provincial Key Lab of Semiconductors and Applications, Department of Physics, Xiamen University, Xiamen, Fujian 361005 (China); State Key Lab of Silicon Materials, Zhejiang University, Hangzhou 310027 (China); Yang, Qianqian [Fujian Provincial Key Lab of Semiconductors and Applications, Department of Physics, Xiamen University, Xiamen, Fujian 361005 (China); State Key Lab of Silicon Materials, Zhejiang University, Hangzhou 310027 (China); Zhang, Chunjing; Kong, Lingqi; Li, Shuping; Kang, Junyong [Fujian Provincial Key Lab of Semiconductors and Applications, Department of Physics, Xiamen University, Xiamen, Fujian 361005 (China)

    2013-06-01

    Silver nanoparticle arrays with 2-dimensional hexagonal arrangement were fabricated on the silicon substrates by nanosphere lithography. The silver film was deposited either by thermal evaporation or by magnetron sputtering under different conditions. The nanostructures of the achieved sphere template and the array units were characterized by scanning electron microscopy and atomic force microscopy, and were found to be anomalous under different deposition parameters. Comparative study indicated that the formation of the various 2-dimensional silver nanoparticle array structures was dominated by the thermal energy (temperature), kinetic energy and deposition direction of the deposited metal atoms as well as the size and nanocurvature of the colloidal particles and the metal clusters. - Highlights: • Silver nanoparticle arrays with different nanostructures on silicon substrates. • Various deposition parameters in arrays formation systematically examined. • Possible mechanisms and optimization of nanostructures formation addressed.

  4. Design of UAVs-Based 3D Antenna Arrays for a Maximum Performance in Terms of Directivity and SLL

    Directory of Open Access Journals (Sweden)

    Jesus Garza

    2016-01-01

    Full Text Available This paper presents a design of UAVs-based 3D antenna arrays for a maximum performance in terms of directivity and side lobe level (SLL. This paper illustrates how to model the UAVs formation flight using 3D nonuniform antenna arrays. This design of 3D antenna arrays considers the optimization of the positions of the antenna elements to model the UAVs formation flight. In this case, a disk patch antenna is chosen to be used as element in each UAV. The disk patch antenna is formulated by the well-known cavity model. The synthesis process is carried out by the method of Differential Evolution for Multiobjective Optimization (DEMO. Furthermore, a comparison of the performance of 3D nonuniform antenna arrays is provided with respect to the most conventional arrays (circular, planar, linear, and the cubic for UAVs formation flight.

  5. Laser-induced superhydrophobic grid patterns on PDMS for droplet arrays formation

    Energy Technology Data Exchange (ETDEWEB)

    Farshchian, Bahador [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Gatabi, Javad R. [Materials Science, Engineering and Commercialization, Texas State University, San Marcos, TX 78666 (United States); Bernick, Steven M.; Park, Sooyeon [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Lee, Gwan-Hyoung [Department of Materials Science and Engineering, Yonsei University, Seoul 03722 (Korea, Republic of); Droopad, Ravindranath [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States); Materials Science, Engineering and Commercialization, Texas State University, San Marcos, TX 78666 (United States); Kim, Namwon, E-mail: n_k43@txstate.edu [Ingram School of Engineering, Texas State University, San Marcos, TX 78666 (United States)

    2017-02-28

    Highlights: • Superhydrophobic grid patterns were processed on the surface of PDMS using a pulsed nanosecond laser. • Droplet arrays form instantly on the laser-patterned PDMS with the superhydrophobic grid pattern when the PDMS sample is simply immersed in and withdrawn from water. • Droplet size can be controlled by controlling the pitch size of superhydrophobic grid and the withdrawal speed. - Abstract: We demonstrate a facile single step laser treatment process to render a polydimethylsiloxane (PDMS) surface superhydrophobic. By synchronizing a pulsed nanosecond laser source with a motorized stage, superhydrophobic grid patterns were written on the surface of PDMS. Hierarchical micro and nanostructures were formed in the irradiated areas while non-irradiated areas were covered by nanostructures due to deposition of ablated particles. Arrays of droplets form spontaneously on the laser-patterned PDMS with superhydrophobic grid pattern when the PDMS sample is simply immersed in and withdrawn from water due to different wetting properties of the irradiated and non-irradiated areas. The effects of withdrawal speed and pitch size of superhydrophobic grid on the size of formed droplets were investigated experimentally. The droplet size increases initially with increasing the withdrawal speed and then does not change significantly beyond certain points. Moreover, larger droplets are formed by increasing the pitch size of the superhydrophobic grid. The droplet arrays formed on the laser-patterned PDMS with wettability contrast can be used potentially for patterning of particles, chemicals, and bio-molecules and also for cell screening applications.

  6. Non-lift-off block copolymer lithography of 25 nm magnetic nanodot arrays.

    Science.gov (United States)

    Baruth, A; Rodwogin, Marc D; Shankar, A; Erickson, M J; Hillmyer, Marc A; Leighton, C

    2011-09-01

    Although nanolithographic techniques based on self-assembled block copolymer templates offer tremendous potential for fabrication of large-area nanostructure arrays, significant difficulties arise with both the lift-off and etch processes typically used for pattern transfer. These become progressively more important in the limit of extreme feature sizes. The few techniques that have been developed to avoid these issues are quite complex. Here, we demonstrate successful execution of a nanolithographic process based on solvent annealed, cylinder-forming, easily degradable, polystyrene-b-polylactide block copolymer films that completely avoids lift-off in addition to the most challenging aspects of etching. We report a "Damascene-type" process that overfills the polystyrene template with magnetic metal, employs ion beam milling to planarize the metal surface down to the underlying polystyrene template, then exploits the large etch rate contrast between polystyrene and typical metals to generate pattern reversal of the original template into the magnetic metal. The process is demonstrated via formation of a large-area array of 25 nm diameter ferromagnetic Ni(80)Fe(20) nanodots with hexagonally close-packed order. Extensive microscopy, magnetometry, and electrical measurements provide detailed characterization of the pattern formation. We argue that the approach is generalizable to a wide variety of materials, is scalable to smaller feature sizes, and critically, minimizes etch damage, thus preserving the essential functionality of the patterned material.

  7. Development of high sensitivity eight-element multiplexed fiber laser acoustic pressure hydrophone array and interrogation system

    Science.gov (United States)

    Li, Ming; Sun, Zhihui; Zhang, Xiaolei; Li, Shujuan; Song, Zhiqiang; Wang, Meng; Guo, Jian; Ni, Jiasheng; Wang, Chang; Peng, Gangding; Xu, Xiangang

    2017-09-01

    Fiber laser hydrophones have got widespread concerns due to the unique advantages and broad application prospects. In this paper, the research results of the eight-element multiplexed fiber laser acoustic pressure array and the interrogation system are introduced, containing low-noise distributed feedback fiber laser (DFB-FL) fabrication, sensitivity enhancement packaging, and interferometric signal demodulation. The frequency response range of the system is 10Hz-10kHz, the laser frequency acoustic pressure sensitivity reaches 115 dB re Hz/Pa, and the equivalent noise acoustic pressure is less than 60μPa/Hz1/2. The dynamic range of the system is greater than 120 dB.

  8. Type I X-ray bursts, burst oscillations and kHz quasi-periodic oscillations in the neutron star system IGR J17191−2821

    NARCIS (Netherlands)

    Altamirano, D.; Linares, M.; Patruno, A.; Degenaar, N.; Wijnands, R.; Klein-Wolt, M.; van der Klis, M.; Markwardt, C.; Swank, J.

    2010-01-01

    We present a detailed study of the X-ray energy and power spectral properties of the neutron star transient IGR J17191−2821. We discovered four instances of pairs of simultaneous kilohertz quasi-periodic oscillations (kHz QPOs). The frequency difference between these kHz QPOs is between 315 and 362

  9. Recrystallized arrays of bismuth nanowires with trigonal orientation.

    Science.gov (United States)

    Limmer, Steven J; Yelton, W Graham; Erickson, Kristopher J; Medlin, Douglas L; Siegal, Michael P

    2014-01-01

    We demonstrate methods to improve the crystalline-quality of free-standing Bi nanowires arrays on a Si substrate and enhance the preferred trigonal orientation for thermoelectric performance by annealing the arrays above the 271.4 °C Bi melting point. The nanowires maintain their geometry during melting due to the formation of a thin Bi-oxide protective shell that contains the molten Bi. Recrystallizing nanowires from the melt improves crystallinity; those cooled rapidly demonstrate a strong trigonal orientation preference.

  10. Fully Integrated Linear Single Photon Avalanche Diode (SPAD) Array with Parallel Readout Circuit in a Standard 180 nm CMOS Process

    Science.gov (United States)

    Isaak, S.; Bull, S.; Pitter, M. C.; Harrison, Ian.

    2011-05-01

    This paper reports on the development of a SPAD device and its subsequent use in an actively quenched single photon counting imaging system, and was fabricated in a UMC 0.18 μm CMOS process. A low-doped p- guard ring (t-well layer) encircling the active area to prevent the premature reverse breakdown. The array is a 16×1 parallel output SPAD array, which comprises of an active quenched SPAD circuit in each pixel with the current value being set by an external resistor RRef = 300 kΩ. The SPAD I-V response, ID was found to slowly increase until VBD was reached at excess bias voltage, Ve = 11.03 V, and then rapidly increase due to avalanche multiplication. Digital circuitry to control the SPAD array and perform the necessary data processing was designed in VHDL and implemented on a FPGA chip. At room temperature, the dark count was found to be approximately 13 KHz for most of the 16 SPAD pixels and the dead time was estimated to be 40 ns.

  11. Micropatterned arrays of porous silicon: toward sensory biointerfaces.

    Science.gov (United States)

    Flavel, Benjamin S; Sweetman, Martin J; Shearer, Cameron J; Shapter, Joseph G; Voelcker, Nicolas H

    2011-07-01

    We describe the fabrication of arrays of porous silicon spots by means of photolithography where a positive photoresist serves as a mask during the anodization process. In particular, photoluminescent arrays and porous silicon spots suitable for further chemical modification and the attachment of human cells were created. The produced arrays of porous silicon were chemically modified by means of a thermal hydrosilylation reaction that facilitated immobilization of the fluorescent dye lissamine, and alternatively, the cell adhesion peptide arginine-glycine-aspartic acid-serine. The latter modification enabled the selective attachment of human lens epithelial cells on the peptide functionalized regions of the patterns. This type of surface patterning, using etched porous silicon arrays functionalized with biological recognition elements, presents a new format of interfacing porous silicon with mammalian cells. Porous silicon arrays with photoluminescent properties produced by this patterning strategy also have potential applications as platforms for in situ monitoring of cell behavior.

  12. ArrayExpress update--trends in database growth and links to data analysis tools.

    Science.gov (United States)

    Rustici, Gabriella; Kolesnikov, Nikolay; Brandizi, Marco; Burdett, Tony; Dylag, Miroslaw; Emam, Ibrahim; Farne, Anna; Hastings, Emma; Ison, Jon; Keays, Maria; Kurbatova, Natalja; Malone, James; Mani, Roby; Mupo, Annalisa; Pedro Pereira, Rui; Pilicheva, Ekaterina; Rung, Johan; Sharma, Anjan; Tang, Y Amy; Ternent, Tobias; Tikhonov, Andrew; Welter, Danielle; Williams, Eleanor; Brazma, Alvis; Parkinson, Helen; Sarkans, Ugis

    2013-01-01

    The ArrayExpress Archive of Functional Genomics Data (http://www.ebi.ac.uk/arrayexpress) is one of three international functional genomics public data repositories, alongside the Gene Expression Omnibus at NCBI and the DDBJ Omics Archive, supporting peer-reviewed publications. It accepts data generated by sequencing or array-based technologies and currently contains data from almost a million assays, from over 30 000 experiments. The proportion of sequencing-based submissions has grown significantly over the last 2 years and has reached, in 2012, 15% of all new data. All data are available from ArrayExpress in MAGE-TAB format, which allows robust linking to data analysis and visualization tools, including Bioconductor and GenomeSpace. Additionally, R objects, for microarray data, and binary alignment format files, for sequencing data, have been generated for a significant proportion of ArrayExpress data.

  13. High power all-solid-state fourth harmonic generation of 266 nm at the pulse repetition rate of 100 kHz

    International Nuclear Information System (INIS)

    Liu, Q; Yan, X P; Fu, X; Gong, M; Wang, D S

    2009-01-01

    14.8 W UV laser at 266 nm was reported with the extra cavity frequency quartered configuration. The fundamental frequency IR source is a high-power high-beam-quality acoustic-optic Q-switched Nd:YVO 4 master-oscillator-power-amplifier laser. The type-I phase-matched LBO and type-I phase-matched BBO crystals were used as the extra-cavity frequency doubled and quartered crystal respectively. 14.8 W UV laser of 266 nm was obtained at the pulse repetition rate of 100 kHz with the conversion efficiency of 18.3% from green to UV, and the pulse duration of the UV laser was 10 ns corresponding to the pulse peak power of 14.8 kW. At 150 kHz, 11.5 W power output was obtained. The highest peak power of 21 kW was also achieved at 80 kHz with the average output power of 14.5 W

  14. Densities and Kinematic Viscosities for the Systems Benzene + Methyl Formate, Benzene + Ethyl Formate, Benzene + Propyl Formate, and Benzene + Butyl Formate

    DEFF Research Database (Denmark)

    Emmerling, Uwe; Rasmussen, Peter

    1998-01-01

    a Redlich-Kister type of expression with temperature-independent parameters and the data for the systems benzene + ethyl formate, benzene + propyl formate, and benzene + butyl formate with temperature-dependent parameters. The viscosities have furthermore been compared to values predicted by means of the GC......Densities and kinematic viscosities have been measured for the system benzene + methyl formate at 20°C and for the systems benzene + ethyl formate, benzene + propyl formate, and benzene + butyl formate from 20°C to 50°C. The results for the system benzene + methyl formate have been correlated using...

  15. Laser-filamentation-induced condensation and snow formation in a cloud chamber.

    Science.gov (United States)

    Ju, Jingjing; Liu, Jiansheng; Wang, Cheng; Sun, Haiyi; Wang, Wentao; Ge, Xiaochun; Li, Chuang; Chin, See Leang; Li, Ruxin; Xu, Zhizhan

    2012-04-01

    Using 1 kHz, 9 mJ femtosecond laser pulses, we demonstrate laser-filamentation-induced spectacular snow formation in a cloud chamber. An intense updraft of warm moist air is generated owing to the continuous heating by the high-repetition filamentation. As it encounters the cold air above, water condensation and large-sized particles spread unevenly across the whole cloud chamber via convection and cyclone like action on a macroscopic scale. This indicates that high-repetition filamentation plays a significant role in macroscopic laser-induced water condensation and snow formation.

  16. Single-Step Fabrication of High-Density Microdroplet Arrays of Low-Surface-Tension Liquids.

    Science.gov (United States)

    Feng, Wenqian; Li, Linxian; Du, Xin; Welle, Alexander; Levkin, Pavel A

    2016-04-01

    A facile approach for surface patterning that enables single-step fabrication of high-density arrays of low-surface-tension organic-liquid microdroplets is described. This approach enables miniaturized and parallel high-throughput screenings in organic solvents, formation of homogeneous arrays of hydrophobic nanoparticles, polymer micropads of specific shapes, and polymer microlens arrays. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Self-organized criticality paradigm

    International Nuclear Information System (INIS)

    Duran, I.; Stoeckel, J.; Hron, M.; Horacek, J.; Jakubka, K.; Kryska, L.

    2000-01-01

    According to the paradigm of the Self-Organized Criticality (SOC), the anomalous transport in tokamaks is caused by fast transient processes - avalanches. One of the manifestations of these phenomena should be 1/f decay of electrostatic fluctuations power spectra in a certain frequency range. In this paper, the frequency spectra of floating potential, density and fluctuation-induced flux, measured by poloidal and radial arrays of Langmuir probes on the CASTOR tokamak, are presented. The floating potential and the fluctuation-induced flux decay from 30 kHz up to 100 kHz as f -1 . The plasma density decays as f -1 in a more narrow band, 20 to 40 kHz. The possible limitation of SOC behavior for frequencies higher than 100 kHz due to intermittency is stressed. For this reason the Probability Distribution Functions (PDFs) of floating potential fluctuations were computed at different time scales using wavelet transform. A clear departure of the computed PDFs from Gaussianity, which is a classical signature of intermittency, is observed at time scales under 10 μs (100 kHz). (author)

  18. Configuration Considerations for Low Frequency Arrays

    Science.gov (United States)

    Lonsdale, C. J.

    2005-12-01

    The advance of digital signal processing capabilities has spurred a new effort to exploit the lowest radio frequencies observable from the ground, from ˜10 MHz to a few hundred MHz. Multiple scientifically and technically complementary instruments are planned, including the Mileura Widefield Array (MWA) in the 80-300 MHz range, and the Long Wavelength Array (LWA) in the 20-80 MHz range. The latter instrument will target relatively high angular resolution, and baselines up to a few hundred km. An important practical question for the design of such an array is how to distribute the collecting area on the ground. The answer to this question profoundly affects both cost and performance. In this contribution, the factors which determine the anticipated performance of any such array are examined, paying particular attention to the viability and accuracy of array calibration. It is argued that due to the severity of ionospheric effects in particular, it will be difficult or impossible to achieve routine, high dynamic range imaging with a geographically large low frequency array, unless a large number of physically separate array stations is built. This conclusion is general, is based on the need for adequate sampling of ionospheric irregularities, and is independent of the calibration algorithms and techniques that might be employed. It is further argued that array configuration figures of merit that are traditionally used for higher frequency arrays are inappropriate, and a different set of criteria are proposed.

  19. Development of an automation technique for the establishment of functional lipid bilayer arrays

    International Nuclear Information System (INIS)

    Hansen, J S; Vogel, J; Geschke, O; Emnéus, J; Nielsen, C H; Perry, M; Vissing, T; Hansen, C R

    2009-01-01

    In the present work, a technique for establishing multiple black lipid membranes (BLMs) in arrays of micro structured ethylene tetrafluoroethylene (ETFE) films, and supported by a micro porous material was developed. Rectangular 8 × 8 arrays with apertures having diameters of 301 ± 5 µm were fabricated in ETFE Teflon film by laser ablation using a carbon dioxide laser. Multiple lipid membranes could be formed across the micro structured 8 × 8 array ETFE partitions. Success rates for the establishment of cellulose-supported BLMs across the multiple aperture arrays were above 95%. However, the time course of the membrane thinning process was found to vary considerably between multiple aperture bilayer experiments. An airbrush partition pretreatment technique was developed to increase the reproducibility of the multiple lipid bilayers formation during the time course from the establishment of the lipid membranes to the formation of bilayers. The results showed that multiple lipid bilayers could be reproducible formed across the airbrush-pretreated 8 × 8 rectangular arrays. The ionophoric peptide valinomycin was incorporated into established membrane arrays, resulting in ionic currents that could be effectively blocked by tetraethylammonium. This shows that functional bimolecular lipid membranes were established, and furthermore outlines that the established lipid membrane arrays could host functional membrane-spanning molecules

  20. Low-cost solar array progress and plans

    Science.gov (United States)

    Callaghan, W. T.

    It is pointed out that significant redirection has occurred in the U.S. Department of Energy (DOE) Photovoltaics Program, and thus in the Flat-Plate Solar Array Project (FSA), since the 3rd European Communities Conference. The Silicon Materials Task has now the objective to sponsor theoretical and experimental research on silicon material refinement technology suitable for photovoltaic flat-plate solar arrays. With respect to the hydrochlorination reaction, a process proof of concept was completed through definition of reaction kinetics, catalyst, and reaction characteristics. In connection with the dichlorosilane chemical vapor desposition process, a preliminary design was completed of an experimental process system development unit with a capacity of 100 to 200 MT/yr of Si.Attention is also given to the silicon-sheet formation research area, environmental isolation research, the cell and module formation task, the engineering sciences area, and the module performance and failure analysis area.

  1. Feedhorn-Coupled Transition-Edge Superconducting Bolometer Arrays for Cosmic Microwave Background Polarimetry

    Science.gov (United States)

    Hubmayr, J.; Austermann, J.; Beall, J.; Becker, D.; Cho, H.-M.; Datta, R.; Duff, S. M.; Grace, E.; Halverson, N.; Henderson, S. W.; hide

    2015-01-01

    NIST produces large-format, dual-polarization-sensitive detector arrays for a broad range of frequencies (30-1400 GHz). Such arrays enable a host of astrophysical measurements. Detectors optimized for cosmic microwave background observations are monolithic, polarization-sensitive arrays based on feedhorn and planar Nb antenna-coupled transition-edge superconducting (TES) bolometers. Recent designs achieve multiband, polarimetric sensing within each spatial pixel. In this proceeding, we describe our multichroic, feedhorn-coupled design; demonstrate performance at 70-380 GHz; and comment on current developments for implementation of these detector arrays in the advanced Atacama Cosmology Telescope receiver

  2. High-resolution SNP array analysis of patients with developmental disorder and normal array CGH results

    Directory of Open Access Journals (Sweden)

    Siggberg Linda

    2012-09-01

    Full Text Available Abstract Background Diagnostic analysis of patients with developmental disorders has improved over recent years largely due to the use of microarray technology. Array methods that facilitate copy number analysis have enabled the diagnosis of up to 20% more patients with previously normal karyotyping results. A substantial number of patients remain undiagnosed, however. Methods and Results Using the Genome-Wide Human SNP array 6.0, we analyzed 35 patients with a developmental disorder of unknown cause and normal array comparative genomic hybridization (array CGH results, in order to characterize previously undefined genomic aberrations. We detected no seemingly pathogenic copy number aberrations. Most of the vast amount of data produced by the array was polymorphic and non-informative. Filtering of this data, based on copy number variant (CNV population frequencies as well as phenotypically relevant genes, enabled pinpointing regions of allelic homozygosity that included candidate genes correlating to the phenotypic features in four patients, but results could not be confirmed. Conclusions In this study, the use of an ultra high-resolution SNP array did not contribute to further diagnose patients with developmental disorders of unknown cause. The statistical power of these results is limited by the small size of the patient cohort, and interpretation of these negative results can only be applied to the patients studied here. We present the results of our study and the recurrence of clustered allelic homozygosity present in this material, as detected by the SNP 6.0 array.

  3. Optical Sensing with Simultaneous Electrochemical Control in Metal Nanowire Arrays

    Directory of Open Access Journals (Sweden)

    Janos Vörös

    2010-11-01

    Full Text Available This work explores the alternative use of noble metal nanowire systems in large-scale array configurations to exploit both the nanowires’ conductive nature and localized surface plasmon resonance (LSPR. The first known nanowire-based system has been constructed, with which optical signals are influenced by the simultaneous application of electrochemical potentials. Optical characterization of nanowire arrays was performed by measuring the bulk refractive index sensitivity and the limit of detection. The formation of an electrical double layer was controlled in NaCl solutions to study the effect of local refractive index changes on the spectral response. Resonance peak shifts of over 4 nm, a bulk refractive index sensitivity up to 115 nm/RIU and a limit of detection as low as 4.5 × 10−4 RIU were obtained for gold nanowire arrays. Simulations with the Multiple Multipole Program (MMP confirm such bulk refractive index sensitivities. Initial experiments demonstrated successful optical biosensing using a novel form of particle-based nanowire arrays. In addition, the formation of an ionic layer (Stern-layer upon applying an electrochemical potential was also monitored by the shift of the plasmon resonance.

  4. Inhibition of Steptococcus mutans biofilm formation by extracts of Tenacibaculum sp. 20J, a bacterium with wide-spectrum quorum quenching activity

    Science.gov (United States)

    Muras, Andrea; Mayer, Celia; Romero, Manuel; Camino, Tamara; Ferrer, Maria D.; Mira, Alex; Otero, Ana

    2018-01-01

    ABSTRACT Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhibitory activity was tested with the biosensors Vibrio harveyi BB170 and JMH597. S. mutans ATCC25175 biofilm formation was monitored using impedance real-time measurements with the xCELLigence system®, confocal laser microscopy, and the crystal violet quantification method. Results: The addition of the cell extract from Tenacibaculum sp. 20J reduced biofilm formation in S. mutans ATCC25175 by 40–50% compared to the control without significantly affecting growth. A decrease of almost 40% was also observed in S. oralis DSM20627 and S. dentisani 7747 biofilms. Conclusions: The ability of Tenacibaculum sp. 20J to interfere with AI-2 and inhibit biofilm formation in S. mutans was demonstrated. The results indicate that the inhibition of quorum sensing processes may constitute a suitable strategy for inhibiting dental plaque formation, although additional experiments using mixed biofilm models would be required. PMID:29410771

  5. ANALYSIS OF CHIP FORMATION DURING HARD TURNING THROUGH ACOUSTIC EMISSION

    Directory of Open Access Journals (Sweden)

    Miroslav Neslušan

    2012-01-01

    Full Text Available The paper deals with analysis of chip formation and related aspects of the chip formation during turning hardened steel 100Cr6. The paper draws a comparison of some aspects of the chip formation between turning annealed and hardened roll bearing steel. The results of the analysis show that there is the formation of a segmented chip in the case of hard turning. Frequency of segmentation is very high. A conventional piezoelectric dynamometer limits the frequency response to about 3.5 kHz. On the other hand, the frequency of process fluctuation may by obtained by using accelerometers or acoustic emission. This paper reports about the dynamic character of cutting process when hard turning and correlation among the calculated segmentation frequencies and the experimental analysis.

  6. Biofilm formation on a TiO2 nanotube with controlled pore diameter and surface wettability

    International Nuclear Information System (INIS)

    Anitha, V C; Narayan Banerjee, Arghya; Woo Joo, Sang; Lee, Jin-Hyung; Lee, Jintae; Ki Min, Bong

    2015-01-01

    Titania (TiO 2 ) nanotube arrays (TNAs) with different pore diameters (140 − 20 nm) are fabricated via anodization using hydrofluoric acid (HF) containing ethylene glycol (EG) by changing the HF-to-EG volume ratio and the anodization voltage. To evaluate the effects of different pore diameters of TiO 2 nanotubes on bacterial biofilm formation, Shewanella oneidensis (S. oneidensis) MR-1 cells and a crystal-violet biofilm assay are used. The surface roughness and wettability of the TNA surfaces as a function of pore diameter, measured via the contact angle and AFM techniques, are correlated with the controlled biofilm formation. Biofilm formation increases with the decreasing nanotube pore diameter, and a 20 nm TiO 2 nanotube shows the maximum biofilm formation. The measurements revealed that 20 nm surfaces have the least hydrophilicity with the highest surface roughness of ∼17 nm and that they show almost a 90% increase in the effective surface area relative to the 140 nm TNAs, which stimulate the cells more effectively to produce the pili to attach to the surface for more biofilm formation. The results demonstrate that bacterial cell adhesion (and hence, biofilm formation) can effectively be controlled by tuning the roughness and wettability of TNAs via controlling the pore diameters of TNA surfaces. This biofilm formation as a function of the surface properties of TNAs can be a potential candidate for both medical applications and as electrodes in microbial fuel cells. (paper)

  7. Active Sensor for Microwave Tissue Imaging with Bias-Switched Arrays.

    Science.gov (United States)

    Foroutan, Farzad; Nikolova, Natalia K

    2018-05-06

    A prototype of a bias-switched active sensor was developed and measured to establish the achievable dynamic range in a new generation of active arrays for microwave tissue imaging. The sensor integrates a printed slot antenna, a low-noise amplifier (LNA) and an active mixer in a single unit, which is sufficiently small to enable inter-sensor separation distance as small as 12 mm. The sensor’s input covers the bandwidth from 3 GHz to 7.5 GHz. Its output intermediate frequency (IF) is 30 MHz. The sensor is controlled by a simple bias-switching circuit, which switches ON and OFF the bias of the LNA and the mixer simultaneously. It was demonstrated experimentally that the dynamic range of the sensor, as determined by its ON and OFF states, is 109 dB and 118 dB at resolution bandwidths of 1 kHz and 100 Hz, respectively.

  8. Array capabilities and future arrays

    International Nuclear Information System (INIS)

    Radford, D.

    1993-01-01

    Early results from the new third-generation instruments GAMMASPHERE and EUROGAM are confirming the expectation that such arrays will have a revolutionary effect on the field of high-spin nuclear structure. When completed, GAMMASHPERE will have a resolving power am order of magnitude greater that of the best second-generation arrays. When combined with other instruments such as particle-detector arrays and fragment mass analysers, the capabilites of the arrays for the study of more exotic nuclei will be further enhanced. In order to better understand the limitations of these instruments, and to design improved future detector systems, it is important to have some intelligible and reliable calculation for the relative resolving power of different instrument designs. The derivation of such a figure of merit will be briefly presented, and the relative sensitivities of arrays currently proposed or under construction presented. The design of TRIGAM, a new third-generation array proposed for Chalk River, will also be discussed. It is instructive to consider how far arrays of Compton-suppressed Ge detectors could be taken. For example, it will be shown that an idealised open-quote perfectclose quotes third-generation array of 1000 detectors has a sensitivity an order of magnitude higher again than that of GAMMASPHERE. Less conventional options for new arrays will also be explored

  9. Array processors: an introduction to their architecture, software, and applications in nuclear medicine

    International Nuclear Information System (INIS)

    King, M.A.; Doherty, P.W.; Rosenberg, R.J.; Cool, S.L.

    1983-01-01

    Array processors are ''number crunchers'' that dramatically enhance the processing power of nuclear medicine computer systems for applicatons dealing with the repetitive operations involved in digital image processing of large segments of data. The general architecture and the programming of array processors are introduced, along with some applications of array processors to the reconstruction of emission tomographic images, digital image enhancement, and functional image formation

  10. Real time processor for array speckle interferometry

    International Nuclear Information System (INIS)

    Chin, G.; Florez, J.; Borelli, R.; Fong, W.; Miko, J.; Trujillo, C.

    1989-01-01

    With the construction of several new large aperture telescopes and the development of large format array detectors in the near IR, the ability to obtain diffraction limited seeing via IR array speckle interferometry offers a powerful tool. We are constructing a real-time processor to acquire image frames, perform array flat-fielding, execute a 64 x 64 element 2D complex FFT, and to average the power spectrum all within the 25 msec coherence time for speckles at near IR wavelength. The processor is a compact unit controlled by a PC with real time display and data storage capability. It provides the ability to optimize observations and obtain results on the telescope rather than waiting several weeks before the data can be analyzed and viewed with off-line methods

  11. Making the invisible visible: improved electrospray ion formation of metalloporphyrins/-phthalocyanines by attachment of the formate anion (HCOO(-)).

    Science.gov (United States)

    Hitzenberger, Jakob Felix; Dammann, Claudia; Lang, Nina; Lungerich, Dominik; García-Iglesias, Miguel; Bottari, Giovanni; Torres, Tomás; Jux, Norbert; Drewello, Thomas

    2016-02-21

    A protocol is developed for the coordination of the formate anion (HCOO(-)) to neutral metalloporphyrins (Pors) and -phthalocyanines (Pcs) containing divalent metals as a means to improve their ion formation in electrospray ionization (ESI). This method is particularly useful when the oxidation of the neutral metallomacrocycle fails. While focusing on Zn(II)Pors and Zn(II)Pcs, we show that formate is also readily attached to Mn(II), Mg(II) and Co(II)Pcs. However, for the Co(II)Pc secondary reactions can be observed. Upon collision-induced dissociation (CID), Zn(II)Por/Pc·formate supramolecular complexes can undergo the loss of CO2 in combination with transfer of a hydride anion (H(-)) to the zinc metal center. Further dissociation leads to electron transfer and hydrogen atom loss, generating a route to the radical anion of the Zn(II)Por/Pc without the need for electrochemical reduction, although the Zn(II)Por/Pc may have a too low electron affinity to allow electron transfer directly from the formate anion. In addition to single Por molecules, multi Por arrays were successfully analyzed by this method. In this case, multiple addition of formate occurs, giving rise to multiply charged species. In these multi Por arrays, complexation of the formate anion occurs by two surrounding Por units (sandwich). Therefore, the maximum attainment of formate anions in these arrays corresponds to the number of such sandwich complexes rather than the number of porphyrin moieties. The same bonding motif leads to dimers of the composition [(Zn(II)Por/Pc)2·HCOO](-). In these, the formate anion can act as a structural probe, allowing the distinction of isomeric ions with the formate bridging two macrocycles or being attached to a dimer of directly connected macrocycles.

  12. A High Power Boost Converter for PV Systems Operating up to 300 kHz using SiC Devices

    DEFF Research Database (Denmark)

    Anthon, Alexander; Zhang, Zhe; Andersen, Michael A. E.

    2014-01-01

    In this paper, a 3kW boost converter for PV applications using SiC devices is introduced. Main focus is to operate the converter over a wide range of switching frequency and to analyze the main loss distributors as well as the efficiency. The switching element is a recently introduced normally...... be operated at full power for a switching frequency of 100 kHz using natural cooling. At 200 kHz the boost converter is capable of operating at full power when forced air cooling is applied having a JFET case temperature of less than 90 C. The case temperature of the JFET increases up to 110 C at a switching...

  13. Fabrication and characterization of CaP-coated nanotube arrays

    International Nuclear Information System (INIS)

    Kung, Kuan-Chen; Chen, Jia-Ling; Liu, Yen-Ting; Lee, Tzer-Min

    2015-01-01

    Modified anodization techniques have been shown to improve the biocompatibility of titanium. This study demonstrated the anodic formation of self-organized nanotube arrays on titanium from an electrolyte solution containing 1 M H 3 PO 4 and 1 wt% hydrofluoric acid (HF). Our aim was to investigate the effects of sputter-deposited CaP on nanotube arrays. SEM images revealed a surface with uniform morphology and an average pore diameter of 29 nm. XRD results indicated that the phase of the nanotube arrays was amorphous. Electron spectroscopy for chemical analysis (ESCA) confirmed that the nanotube arrays were coated with calcium and phosphorus. Cell culture experiments using human osteosarcoma (HOS) cells demonstrated that the CaP/nanotube arrays had a pronounced effect on initial cell attachment as well as on the number of cells at 1, 7, and 14 days. Compared to as-polished titanium, the CaP/nanotube arrays accelerated cell proliferation, attachment, and spreading. Our results demonstrate the pronounced effects of CaP/nanotube arrays on the biological responses of HOS cells. - Highlights: • Self-organized nanotube arrays were anodically formed on titanium. • Surfaces of nanotube arrays exhibited uniform morphology and pore size. • According to ESCA results, Ca and P were successfully coated on nanotube arrays. • CaP/nanotube arrays accelerated the attachment and spreading of cells. • CaP/nanotube arrays were shown to affect biological responses of cells

  14. Fabrication and characterization of CaP-coated nanotube arrays

    Energy Technology Data Exchange (ETDEWEB)

    Kung, Kuan-Chen; Chen, Jia-Ling [Institute of Oral Medicine, National Cheng Kung University, Tainan 701, Taiwan (China); Liu, Yen-Ting [Department of Materials Science and Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Lee, Tzer-Min, E-mail: tmlee@mail.ncku.edu.tw [Institute of Oral Medicine, National Cheng Kung University, Tainan 701, Taiwan (China); Medical Device Innovation Center, National Cheng Kung University, Tainan 701, Taiwan (China); School of Dentistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan (China)

    2015-03-01

    Modified anodization techniques have been shown to improve the biocompatibility of titanium. This study demonstrated the anodic formation of self-organized nanotube arrays on titanium from an electrolyte solution containing 1 M H{sub 3}PO{sub 4} and 1 wt% hydrofluoric acid (HF). Our aim was to investigate the effects of sputter-deposited CaP on nanotube arrays. SEM images revealed a surface with uniform morphology and an average pore diameter of 29 nm. XRD results indicated that the phase of the nanotube arrays was amorphous. Electron spectroscopy for chemical analysis (ESCA) confirmed that the nanotube arrays were coated with calcium and phosphorus. Cell culture experiments using human osteosarcoma (HOS) cells demonstrated that the CaP/nanotube arrays had a pronounced effect on initial cell attachment as well as on the number of cells at 1, 7, and 14 days. Compared to as-polished titanium, the CaP/nanotube arrays accelerated cell proliferation, attachment, and spreading. Our results demonstrate the pronounced effects of CaP/nanotube arrays on the biological responses of HOS cells. - Highlights: • Self-organized nanotube arrays were anodically formed on titanium. • Surfaces of nanotube arrays exhibited uniform morphology and pore size. • According to ESCA results, Ca and P were successfully coated on nanotube arrays. • CaP/nanotube arrays accelerated the attachment and spreading of cells. • CaP/nanotube arrays were shown to affect biological responses of cells.

  15. A 1372-element Large Scale Hemispherical Ultrasound Phased Array Transducer for Noninvasive Transcranial Therapy

    International Nuclear Information System (INIS)

    Song, Junho; Hynynen, Kullervo

    2009-01-01

    Noninvasive transcranial therapy using high intensity focused ultrasound transducers has attracted high interest as a promising new modality for the treatments of brain related diseases. We describe the development of a 1372 element large scale hemispherical ultrasound phased array transducer operating at a resonant frequency of 306 kHz. The hemispherical array has a diameter of 31 cm and a 15.5 cm radius of curvature. It is constructed with piezoelectric (PZT-4) tube elements of a 10 mm in diameter, 6 mm in length and 1.4 mm wall thickness. Each element is quasi-air backed by attaching a cork-rubber membrane on the back of the element. The acoustic efficiency of the element is determined to be approximately 50%. The large number of the elements delivers high power ultrasound and offers better beam steering and focusing capability. Comparisons of sound pressure-squared field measurements with theoretical calculations in water show that the array provides good beam steering and tight focusing capability over an efficient volume of approximately 100x100x80 mm 3 with nominal focal spot size of approximately 2.3 mm in diameter at -6 dB. We also present its beam steering and focusing capability through an ex vivo human skull by measuring pressure-squared amplitude after phase corrections. These measurements show the same efficient volume range and focal spot sizes at -6 dB as the ones in water without the skull present. These results indicate that the array is sufficient for use in noninvasive transcranial ultrasound therapy.

  16. Suppression of 3D coherent noise by areal geophone array; Menteki jushinki array ni yoru sanjigen coherent noise no yokusei

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, R; Nakagami, K; Tanaka, H [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1996-05-01

    For improving the quality of data collected by reflection seismic exploration, a lattice was deployed at one point of a traverse line, and the data therefrom were used to study the 3D coherent noise suppression effect of the areal array. The test was conducted at a Japan National Oil Corporation test field in Kashiwazaki City, Niigata Prefecture. The deployed lattice had 144 vibration receiving points arrayed at intervals of 8m composing an areal array, and 187 vibration generating points arrayed at intervals of 20m extending over 6.5km. Data was collected at the vibration receiving points in the lattice, each point acting independently from the others, and processed for the composition of a large areal array, with the said data from plural vibration receiving points added up therein. As the result of analysis of the records covering the data collected at the receiving points in the lattice, it is noted that an enlarged areal array leads to a higher S/N ratio and that different reflection waves are emphasized when the array direction is changed. 1 ref., 6 figs.

  17. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    International Nuclear Information System (INIS)

    Sanford, T.W.; Mock, R.C.; Spielman, R.B.; Peterson, D.L.; Mosher, D.; Roderick, N.F.

    1998-01-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. 77, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh - Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of ∼40 TW and energy of ∼325 kJ show little change outside of a ±15% shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak K-shell (lines plus continuum) power of ∼8 TW and energy of ∼70 kJ show little change with radius. The minimal change in K-shell yield is in agreement with simple K-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh - Taylor instability observed in small-wire-number imploding loads. copyright 1998 American Institute of Physics

  18. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    Science.gov (United States)

    Sanford, T. W. L.; Mock, R. C.; Spielman, R. B.; Peterson, D. L.; Mosher, D.; Roderick, N. F.

    1998-10-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. 77, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh-Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of ˜40 TW and energy of ˜325 kJ show little change outside of a ±15% shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak K-shell (lines plus continuum) power of ˜8 TW and energy of ˜70 kJ show little change with radius. The minimal change in K-shell yield is in agreement with simple K-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh-Taylor instability observed in small-wire-number imploding loads.

  19. Seismometer array station processors

    International Nuclear Information System (INIS)

    Key, F.A.; Lea, T.G.; Douglas, A.

    1977-01-01

    A description is given of the design, construction and initial testing of two types of Seismometer Array Station Processor (SASP), one to work with data stored on magnetic tape in analogue form, the other with data in digital form. The purpose of a SASP is to detect the short period P waves recorded by a UK-type array of 20 seismometers and to edit these on to a a digital library tape or disc. The edited data are then processed to obtain a rough location for the source and to produce seismograms (after optimum processing) for analysis by a seismologist. SASPs are an important component in the scheme for monitoring underground explosions advocated by the UK in the Conference of the Committee on Disarmament. With digital input a SASP can operate at 30 times real time using a linear detection process and at 20 times real time using the log detector of Weichert. Although the log detector is slower, it has the advantage over the linear detector that signals with lower signal-to-noise ratio can be detected and spurious large amplitudes are less likely to produce a detection. It is recommended, therefore, that where possible array data should be recorded in digital form for input to a SASP and that the log detector of Weichert be used. Trial runs show that a SASP is capable of detecting signals down to signal-to-noise ratios of about two with very few false detections, and at mid-continental array sites it should be capable of detecting most, if not all, the signals with magnitude above msub(b) 4.5; the UK argues that, given a suitable network, it is realistic to hope that sources of this magnitude and above can be detected and identified by seismological means alone. (author)

  20. Bi-Component Nanostructured Arrays of Co Dots Embedded in Ni80Fe20 Antidot Matrix: Synthesis by Self-Assembling of Polystyrene Nanospheres and Magnetic Properties.

    Science.gov (United States)

    Coïsson, Marco; Celegato, Federica; Barrera, Gabriele; Conta, Gianluca; Magni, Alessandro; Tiberto, Paola

    2017-08-23

    A bi-component nanostructured system composed by a Co dot array embedded in a Ni 80 Fe 20 antidot matrix has been prepared by means of the self-assembling polystyrene nanospheres lithography technique. Reference samples constituted by the sole Co dots or Ni 80 Fe 20 antidots have also been prepared, in order to compare their properties with those of the bi-component material. The coupling between the two ferromagnetic elements has been studied by means of magnetic and magneto-transport measurements. The Ni 80 Fe 20 matrix turned out to affect the vortex nucleation field of the Co dots, which in turn modifies the magneto-resistance behaviour of the system and its spinwave properties.

  1. Ferrite-free high power electrodeless fluorescent lamp operated at a frequency of 160-1000 kHz

    International Nuclear Information System (INIS)

    Popov, Oleg A; Chandler, Robert

    2002-01-01

    An electrodeless ferrite-free fluorescent lamp of a closed-loop type ('tokamak') was studied at a driving frequency, f = 160-1000 kHz, and power of 100-250 W. The inductive discharge was ignited in the mercury-argon mixture with the help of an induction coil of several (7-15) turns made from multiple-strand (Litz) wire. The discharge parameters - current, resistance, and electric field - were calculated using the transformer model of an RF inductive discharge. They were found to be close to those measured in a plasma of a 'tokamak'-type lamp operated at the same frequency and RF power but with the use of the ferrite cores. The ferrite-free lamp had high luminous efficacy as high as 85 LPW at a frequency, f>200 kHz, and power of 100-200 W. Such a high efficacy is attributed to low coil power losses ( 90%

  2. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes.

    Directory of Open Access Journals (Sweden)

    Kaitlin M Stimpson

    2010-08-01

    Full Text Available Genome rearrangement often produces chromosomes with two centromeres (dicentrics that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly those in humans, can be quite stable, usually because one centromere is functionally silenced. Molecular mechanisms of centromere inactivation are poorly understood since there are few systems to experimentally create dicentric human chromosomes. Here, we describe a human cell culture model that enriches for de novo dicentrics. We demonstrate that transient disruption of human telomere structure non-randomly produces dicentric fusions involving acrocentric chromosomes. The induced dicentrics vary in structure near fusion breakpoints and like naturally-occurring dicentrics, exhibit various inter-centromeric distances. Many functional dicentrics persist for months after formation. Even those with distantly spaced centromeres remain functionally dicentric for 20 cell generations. Other dicentrics within the population reflect centromere inactivation. In some cases, centromere inactivation occurs by an apparently epigenetic mechanism. In other dicentrics, the size of the alpha-satellite DNA array associated with CENP-A is reduced compared to the same array before dicentric formation. Extra-chromosomal fragments that contained CENP-A often appear in the same cells as dicentrics. Some of these fragments are derived from the same alpha-satellite DNA array as inactivated centromeres. Our results indicate that dicentric human chromosomes undergo alternative fates after formation. Many retain two active centromeres and are stable through multiple cell divisions. Others undergo centromere inactivation. This event occurs within a broad temporal window and can involve deletion of chromatin that marks the locus as a site for CENP-A maintenance/replenishment.

  3. Frequency drift of 3-kHz interplanetary radio emissions: evidence of Fermi accelerated trapped radiation in a small heliosphere?

    International Nuclear Information System (INIS)

    Czechowski, A.; Grzedzielski, S.

    1990-01-01

    Neither the termination shock wave formed where the solar wind ceases to be supersonic, nor the slightly more distant heliopause, where the wind runs into the interstellar medium, have been directly observed, but estimates based on observed cosmic-ray modulations and on pressure balance between the two media suggest that they are 50-200 AU from the Sun. We argue here that the well-known interplanetary radio emission of 2-3 kHz in frequency is trapped in the electromagnetic cavity formed by the heliopause, and furthermore that the fluctuating solar wind will cause the frequency of this trapped radiation to increase at a rate dependent on the geometry of the cavity. Applying this interpretation to the previously unexplained frequency drift, amounting to ∼ 1 kHz yr -1 , of the 3-kHz burst, we estimate an average heliopause distance of 60-100 AU. This agrees with recent data from Pioneer 10 and Voyager 2, suggesting that the termination shock is located at a distance of ∼50 AU, and implies that Voyager 1 may reach the shock in about 1993 and the heliopause as early as 1996. (author)

  4. Model-Based Spectrum Management. Part 1: Modeling and Computation Manual, Version 2.0

    Science.gov (United States)

    2013-12-01

    Frequency list : ( 790.0125, 790.0375, 790.0525, … , 794.9875) (i.e. signals spaced every 25 kHz starting at 790.0125 MHz and ending at 794.9875...20 dB below peak. When a frequency list is used, this bandwidth is applied for every signal within the range. When a signal falls partially in the...power is 0 2 dBm Hz m⋅ . System 1 Spectrum mask: (-0.0125, -20, -0.0075, 0, 0.00750, 0, 0.0125, -20) Frequency list : ( 190.0125, 190.0375

  5. The formation mechanism of mechanically alloyed Fe-20 at% Al powder

    Energy Technology Data Exchange (ETDEWEB)

    Hadef, F., E-mail: hadef77@yahoo.fr [Laboratoire de Recherche sur la Physico-Chimie des Surfaces et Interfaces, LRPCSI, Universite 20 Aout 1955, BP 26, Route d' El-Hadaiek, Skikda 21000 (Algeria); Otmani, A. [Laboratoire de Recherche sur la Physico-Chimie des Surfaces et Interfaces, LRPCSI, Universite 20 Aout 1955, BP 26, Route d' El-Hadaiek, Skikda 21000 (Algeria); Djekoun, A. [Laboratoire de Magnetisme et Spectroscopie des Solides, LM2S, Universite Badji Mokhtar, BP 12 Annaba 23000 (Algeria); Greneche, J.M. [LUNAM, Universite du Maine, Institut des Molecules et Materiaux du Mans, UMR CNRS 6283, 72085 Le Mans (France)

    2013-01-15

    The formation mechanism of the mechanically alloyed Fe-20 at% Al, from elemental Fe and Al powders, has been investigated. The experimental results indicate the formation of a nanocrystalline bcc {alpha}-Fe(Al) solid solution with a lattice parameter close to a{sub {alpha}-Fe(Al)}=0.2890 nm, where each Fe atom is surrounded by (6Fe+2Al) in the first coordination sphere. The reaction mechanism of MA process seems to be controlled by a diffusion phenomenon. Aluminum particles undergo an important refinement to the nanometer scale and then they stick on Fe particles of large sizes. A large number of clear Al/Fe interface areas were generated. The short diffusion path and the presence of high concentration of defects accelerated the solid state reaction. - Highlights: Black-Right-Pointing-Pointer A nanocrystalline bcc {alpha}-Fe(Al) solid solution is formed from elemental Fe and Al powders. Black-Right-Pointing-Pointer The reaction mechanism of MA process seems to be controlled by a diffusion phenomenon. Black-Right-Pointing-Pointer Each Fe atom is surrounded by (6Fe+2Al) in the first coordination sphere.

  6. A general melt-injection-decomposition route to oriented metal oxide nanowire arrays

    International Nuclear Information System (INIS)

    Han, Dongqiang; Zhang, Xinwei; Hua, Zhenghe; Yang, Shaoguang

    2016-01-01

    Highlights: • A general melt-injection-decomposition (MID) route is proposed for the fabrication of oriented metal oxide nanowire arrays. • Four kinds of metal oxide (CuO, Mn_2O_3, Co_3O_4 and Cr_2O_3) nanowire arrays have been realized as examples through the developed MID route. • The mechanism of the developed MID route is discussed using Thermogravimetry and Differential Thermal Analysis technique. • The MID route is a versatile, simple, facile and effective way to prepare different kinds of oriented metal oxide nanowire arrays in the future. - Abstract: In this manuscript, a general melt-injection-decomposition (MID) route has been proposed and realized for the fabrication of oriented metal oxide nanowire arrays. Nitrate was used as the starting materials, which was injected into the nanopores of the anodic aluminum oxide (AAO) membrane through the capillarity action in its liquid state. At higher temperature, the nitrate decomposed into corresponding metal oxide within the nanopores of the AAO membrane. Oriented metal oxide nanowire arrays were formed within the AAO membrane as a result of the confinement of the nanopores. Four kinds of metal oxide (CuO, Mn_2O_3, Co_3O_4 and Cr_2O_3) nanowire arrays are presented here as examples fabricated by this newly developed process. X-ray diffraction, scanning electron microscopy and transmission electron microscopy studies showed clear evidence of the formations of the oriented metal oxide nanowire arrays. Formation mechanism of the metal oxide nanowire arrays is discussed based on the Thermogravimetry and Differential Thermal Analysis measurement results.

  7. Argus: A W-band 16-pixel focal plane array for the Green Bank Telescope

    Science.gov (United States)

    Devaraj, Kiruthika; Church, Sarah; Cleary, Kieran; Frayer, David; Gawande, Rohit; Goldsmith, Paul; Gundersen, Joshua; Harris, Andrew; Kangaslahti, Pekka; Readhead, Tony; Reeves, Rodrigo; Samoska, Lorene; Sieth, Matt; Voll, Patricia

    2015-05-01

    We are building Argus, a 16-pixel square-packed focal plane array that will cover the 75-115.3 GHz frequency range on the Robert C. Byrd Green Bank Telescope (GBT). The primary research area for Argus is the study of star formation within our Galaxy and nearby galaxies. Argus will map key molecules that trace star formation, including carbon monoxide (CO) and hydrogen cyanide (HCN). An additional key science area is astrochemistry, which will be addressed by observing complex molecules in the interstellar medium, and the study of formation of solar systems, which will be addressed by identifying dense pre-stellar cores and by observing comets in our solar system. Argus has a highly scalable architecture and will be a technology path finder for larger arrays. The array is modular in construction, which will allow easy replacement of malfunctioning and poorly performing components.

  8. Experimental investigation of the ribbon-array ablation process

    International Nuclear Information System (INIS)

    Li Zhenghong; Xu Rongkun; Chu Yanyun; Yang Jianlun; Xu Zeping; Ye Fan; Chen Faxin; Xue Feibiao; Ning Jiamin; Qin Yi; Meng Shijian; Hu Qingyuan; Si Fenni; Feng Jinghua; Zhang Faqiang; Chen Jinchuan; Li Linbo; Chen Dingyang; Ding Ning; Zhou Xiuwen

    2013-01-01

    Ablation processes of ribbon-array loads, as well as wire-array loads for comparison, were investigated on Qiangguang-1 accelerator. The ultraviolet framing images indicate that the ribbon-array loads have stable passages of currents, which produce axially uniform ablated plasma. The end-on x-ray framing camera observed the azimuthally modulated distribution of the early ablated ribbon-array plasma and the shrink process of the x-ray radiation region. Magnetic probes measured the total and precursor currents of ribbon-array and wire-array loads, and there exists no evident difference between the precursor currents of the two types of loads. The proportion of the precursor current to the total current is 15% to 20%, and the start time of the precursor current is about 25 ns later than that of the total current. The melting time of the load material is about 16 ns, when the inward drift velocity of the ablated plasma is taken to be 1.5 × 10 7 cm/s.

  9. Estudio de la bioacústica del zorzal andino (Turdus chiguanco con la aplicación del software Audacity, v. 2.0

    Directory of Open Access Journals (Sweden)

    Aldo Hugo Miguel Orellana

    2014-12-01

    Full Text Available Objetivos: Determinar las características bioacústicas del Turdus chiguanco; entre estas, la amplitud, la frecuencia y la duración en las distintas voces. Métodos: Investigación descriptiva en la cual se recolectaron datos bioacústicos durante los años 2011-2012, luego fueron procesados con el software Audacity versión 2.0. Resultados: Se identificaron cuatro tipos de voces: Voz de huida, voz estacionaria, voz de contacto y voz de canto. En la voz de huida, se determinaron valores promedio: amplitud máxima 52,82 dB; amplitud media 0,05 dB; amplitud mínima -13,91 dB; frecuencia máxima 6,8 kHz; frecuencia media 0,63 kHz; frecuencia mínima 0,27 kHz; la duración 1,05 segundos. En la voz estacionaria: amplitud máxima 31,22 dB; amplitud media -0,19 dB; amplitud mínima -16,45 dB; frecuencia máxima 4,31 kHz; frecuencia media 1,63 kHz; frecuencia mínima 0,52 kHz; duración de 0,29 segundos. En la voz de contacto: amplitud máxima 55,22 dB; amplitud media 0,8 dB; amplitud mínima -16,33 dB; frecuencia máxima 2,87 kHz; frecuencia media 0,41 kHz; frecuencia mínima 0,2 kHz; duración 1,28 segundos. Y en la voz de canto: amplitud máxima 50,22 dB; amplitud media 0,08 dB; amplitud mínima -7,38 dB; frecuencia máxima 3,85 kHz; frecuencia media 0,71 kHz; frecuencia mínima 0,33 kHz; duración 1,34 segundos. Conclusiones: El Turdus chiguanco emite cuatro tipos de voces: de huida, estacionaria, de contacto y de canto. Los valores de las variables bioacústicas: amplitud, frecuencia y duración, varían entre los cuatro tipos de voces.

  10. Clinical Outcomes of 1 kHz Subperception Spinal Cord Stimulation in Implanted Patients With Failed Paresthesia-Based Stimulation: Results of a Prospective Randomized Controlled Trial.

    Science.gov (United States)

    North, James M; Hong, Kyung-Soo Jason; Cho, Philip Young

    2016-10-01

    Pain relief via spinal cord stimulation (SCS) has historically revolved around producing paresthesia to replace pain, with success measured by the extent of paresthesia-pain overlap. In a recent murine study, by Shechter et al., showed the superior efficacy of high frequency SCS (1 kHz and 10 kHz) at inhibiting the effects of mechanical hypersensitivity compared to sham or 50 Hz stimulation. In the same study, authors report there were no differences in efficacy between 1 kHz and 10 kHz delivered at subperception stimulation strength (80% of motor threshold). Therefore, we designed a randomized, 2 × 2 crossover study of low frequency supra-perception SCS vs. subperception SCS at 1 kHz frequency in order to test whether subperception stimulation at 1 kHz was sufficient to provide effective pain relief in human subjects. Twenty-two subjects with SCS, and inadequate pain relief based on numeric pain rating scale (NPRS) scores (>5) were enrolled, and observed for total of seven weeks (three weeks of treatment, one week wash off, and another three weeks of treatment). Subjects were asked to rate their pain on NPRS as a primary efficacy variable, and complete the Oswestry Disability Index (ODI) and Patient's Global Impression of Change (PGIC) as secondary outcome measures. Out of 22 subjects that completed the study, 21 subjects (95%) reported improvements in average, best, and worst pain NPRS scores. All NPRS scores were significantly lower with subperception stimulation compared to paresthesia-based stimulation (p paresthesia based stimulation on ODI scores (p = 3.9737 × 10 -5 ) and PGIC scores (p = 3.0396 × 10 -5 ). © 2016 International Neuromodulation Society.

  11. Deposit formation by 20 % (V/V) FAME fuels in premix burner systems; Ablagerungsbildung durch 20% (V/V) FAME-Brennstoffe in Vormischbrennersystemen

    Energy Technology Data Exchange (ETDEWEB)

    Jaschinski, Christian; Rheinberg, Oliver van [OWI Oel-Waerme-Institut GmbH, Aachen (Germany); RWTH Aachen (Germany). An-Institut

    2012-09-15

    In the domestic heating market the development and use of fuels with an increasing share of biogenic or alternative fuels is propagated. Due to the fact, that modern fuel oil burner feature a complex carburation techniques and combustion, changes on the fuel properties and composition can lead to increased emissions or deposit formation therein. Furthermore, the different fuel properties may result in decreased storage stability, which has to be evaluated before introducing them into the market. The scope of the project was to investigate the performance of low-sulfur domestic heating oil (DHO) with up to 20 % v/v FAME on the storage stability and on the use in oil-fired heating systems. The project was split into two major parts. The first part covered a two-year storage of the fuels including sampling and analysis of the fuels every half year. The analysis was conducted according to DIN 51603-1 for the pure DHO and according to DIN SPEC 51603-6 for the blends. It has been shown, that low sulphur domestic heating oil with up to 20 % (V/V) of FAME after two years of storage fits the parameter of the corresponding standards. Furthermore, a new testing method, called 'DGMK-714' derived from the PetroOxy-test (EN 16091) has been defined. With this method for the determination of oxidation stability the fuels can be characterized being comparable to the standardized testing methods of modified Rancimat or PetroOxy. The higher sample volume of the method allows further analysis of the fuel sample after testing for characterization of the fuels. The second part of the project investigated the deposit formation tendencies of the fuels in an idealized testing apparatus and in three different kinds of oil burners. Using the idealized testing apparatus proved an increased tendency of deposit formation during evaporation for an increasing FAME content. However, this tendency could not be observed in the three commercial oil-fired heating systems. A precise fuel

  12. Inflow of atomic gas fuelling star formation

    DEFF Research Database (Denmark)

    Michałowski, M. J.; Gentile, G.; Hjorth, Jeppe

    2016-01-01

    Gamma-ray burst host galaxies are deficient in molecular gas, and show anomalous metal-poor regions close to GRB positions. Using recent Australia Telescope Compact Array (ATCA) Hi observations we show that they have substantial atomic gas reservoirs. This suggests that star formation in these ga......Gamma-ray burst host galaxies are deficient in molecular gas, and show anomalous metal-poor regions close to GRB positions. Using recent Australia Telescope Compact Array (ATCA) Hi observations we show that they have substantial atomic gas reservoirs. This suggests that star formation...... in these galaxies may be fuelled by recent inflow of metal-poor atomic gas. While this process is debated, it can happen in low-metallicity gas near the onset of star formation because gas cooling (necessary for star formation) is faster than the Hi-to-H2 conversion....

  13. Self-organized voids revisited: Experimental verification of the formation mechanism

    International Nuclear Information System (INIS)

    Song Juan; Jiang Yan; Ye Jun-Yi; Qian Meng-Di; Lin Xian; Bian Hua-Dong; Dai Ye; Ma Guo-Hong; Luo Fang-Fang; Chen Qing-Xi; Zhao Quan-Zhong; Qiu Jian-Rong

    2014-01-01

    We conduct several experiments to further clarify the formation mechanism of a self-organized void array induced by a single laser beam, including energy-related experiments, refractive-index-contrast-related experiments, depth-related experiments, and effective-numerical-aperture experiment. These experiments indicate that the interface spherical aberration is indeed responsible for the formation of void arrays. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  14. Using Low-Frequency Phased Arrays to Detect Cracks in Cast Austenitic Piping Components

    International Nuclear Information System (INIS)

    Anderson, Michael T.; Cumblidge, Stephen E.; Doctor, Steven R.

    2005-01-01

    As part of a multi-year program funded by the United States Nuclear Regulatory Commission (US NRC) to address NDE reliability of inservice inspection (ISI) programs, recent studies conducted at the Pacific Northwest National Laboratory (PNNL) in Richland, Washington, have focused on assessing novel NDE approaches for the inspection of coarse-grained, cast stainless steel reactor components. The primary objective of this work is to provide information to the US NRC on the utility, effectiveness and reliability of ultrasonic testing (UT) and eddy current testing (ET) inspection techniques as related to the ISI of primary piping components in pressurized water reactors (PWRs). This paper describes progress, recent developments and early results from an assessment of a portion of this work relating to the ultrasonic low frequency phased array inspection technique. Westinghouse Owner's Group (WOG) cast stainless steel pipe segments with thermal and mechanical fatigue cracks, PNNL samples containing thermal fatigue cracks and several blank vintage specimens having very coarse grains that are representative of early centrifugally cast piping installed in PWRs, are being used for assessing the inspection method. The phased array approach was implemented using an R/D Tech Tomoscan III system operating at 1.0 MHz and 500 kHz, providing composite volumetric images of the samples. Several dual, transmit-receive, custom designed low-frequency arrays are employed in laboratory trials. Results from laboratory studies for assessing detection of thermal and mechanical fatigue cracks in cast stainless steel piping welds are discussed

  15. Synthesis and electrical characterization of Ca2Nd4Ti6O20 ceramics

    Directory of Open Access Journals (Sweden)

    Muhammad Raz

    2016-03-01

    Full Text Available Ca2Nd4Ti6O20, a layered perov skite structured material was synthesized via a chemical (citrate sol-gel route for the first time using nitrates and alkoxide precursors. Phase analysis of a sample sintered at 1625 °C revealed the formation of an orthorhombic (Pbn21 symmetry. The microstructure of the sample after sintering comprised rod-shaped grains of a size of 1.5 to 6.5µm. The room temperature dielectric constant of the sintered sample was 38 at 100 kHz. The remnant polarization (Pr and the coercive field (Ec were about 400 μC/cm2 and 8.4 kV/cm, respectively. Impedance spectroscopy revealed that the capacitance (13.7 pF and activation energy (1.39 eV of the grain boundary was greater than the capacitance (5.7 pF and activation energy (1.13 eV of the grain.

  16. Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2

    NARCIS (Netherlands)

    Cai, Xiaoqiang; Nomura-Kitabayashi, Aya; Cai, Weibin; Yan, Jianyun; Christoffels, Vincent M.; Cai, Chen-Leng

    2011-01-01

    During early embryogenesis, the formation of the cardiac atrioventricular canal (AVC) facilitates the transition of the heart from a linear tube into a chambered organ. However, the genetic pathways underlying this developmental process are poorly understood. The T-box transcription factor Tbx20 is

  17. Micromirror array nanostructures for anticounterfeiting applications

    Science.gov (United States)

    Lee, Robert A.

    2004-06-01

    The optical characteristics of pixellated passive micro mirror arrays are derived and applied in the context of their use as reflective optically variable device (OVD) nanostructures for the protection of documents from counterfeiting. The traditional design variables of foil based diffractive OVDs are shown to be able to be mapped to a corresponding set of design parameters for reflective optical micro mirror array (OMMA) devices. The greatly increased depth characteristics of micro mirror array OVDs provides an opportunity for directly printing the OVD microstructure onto the security document in-line with the normal printing process. The micro mirror array OVD architecture therefore eliminates the need for hot stamping foil as the carrier of the OVD information, thereby reducing costs. The origination of micro mirror array devices via a palette based data format and a combination electron beam lithography and photolithography techniques is discussed via an artwork example and experimental tests. Finally the application of the technology to the design of a generic class of devices which have the interesting property of allowing for both application and customer specific OVD image encoding and data encoding at the end user stage of production is described. Because of the end user nature of the image and data encoding process these devices are particularly well suited to ID document applications and for this reason we refer this new OVD concept as biometric OVD technology.

  18. Preliminary experimental results of tungsten wire-array Z-pinches on primary test stand

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xian-Bin; Zhou, Shao-Tong; Dan, Jia-Kun; Ren, Xiao-Dong, E-mail: amosrxd@163.com; Wang, Kun-Lun; Zhang, Si-Qun; Li, Jing; Xu, Qiang; Cai, Hong-Chun; Duan, Shu-Chao; Ouyang, Kai; Chen, Guang-Hua; Ji, Ce; Wei, Bing; Feng, Shu-Ping; Wang, Meng; Xie, Wei-Ping; Deng, Jian-Jun [Key Laboratory of Pulsed Power, Institute of Fluid Physics, China Academy of Engineering Physics, P.O. Box 919-108, Mianyang, Sichuan 621999 (China); Zhou, Xiu-Wen; Yang, Yi [Research Center of Laser Fusion, China Academy of Engineering Physics, P.O. Box 919-987, Mianyang, Sichuan 621999 (China)

    2015-07-15

    The Primary Test Stand (PTS) developed at the China Academy of Engineering Physics is a 20 TW pulsed power driver, which can deliver a ∼10 MA, 70 ns rise-time (10%–90%) current to a short-circuit load and has important applications in Z-pinch driven inertial confinement fusion and high energy density physics. Preliminary results of tungsten wire-array Z-pinch experiments on PTS are presented. The load geometries investigated include 15-mm-tall cylindrical single and nested arrays with diameter ranging from 13 mm to 30 mm, consisting of 132–300 tungsten wires with 5–10 μm in diameter. Multiple diagnostics were fielded to characterize the x-ray radiation from wire-array Z pinches. The x-ray peak power (∼50 TW) and total radiated energy (∼500 kJ) were obtained from a single 20-mm-diam array with 80-ns stagnation time. The highest x-ray peak power up to 80 TW with 2.4 ns FWHM was achieved by using a nested array with 20-mm outer diameter, and the total x-ray energy from the nested array is comparable to that of single array. Implosion velocity estimated from the time-resolved image measurement exceeds 30 cm/μs. The detailed experimental results and other findings are presented and discussed.

  19. Effects of array arrangements in nano-patterned thin film media

    International Nuclear Information System (INIS)

    El-Hilo, M.

    2010-01-01

    In this work, the effect of different arrays arrangements on the magnetic behaviour of patterned thin film media is simulated. The modeled films consist of 80x80 cobalt grains of uniform diameter (20 nm) distributed into two different array arrangement: hexagonal (triangular) or square arrays. In addition to that, for each array arrangement, two cases of anisotropy orientations, random and textured films are considered. For both array arrangements and media orientations, hysteresis loops at different array separation (d) were simulated. Predictions show that for closely packed films, the shearing effects on the magnetization loop are much larger for the square array arrangement than the hexagonal one. According to these predictions, the bit switching field distribution in interacting 2D systems is much narrower for the hexagonal array arrangement. This result could be very important for high-density magnetic recording where a narrow bit switching field distribution is required.

  20. LINAC DESIGN FOR AN ARRAY OF SOFT X-RAY FREE ELECTRON LASERS

    International Nuclear Information System (INIS)

    Zholents, Alexander A.; Kur, E.; Penn, G.; Qiang, Ji; Venturini, M.; Wells, R. P.

    2008-01-01

    The design of the linac delivering electron bunches into ten independent soft x-ray free electron lasers (FELs) producing light at 1 nm and longer wavelengths is presented. The bunch repetition rate in the linac is 1 MHz and 100 kHz in each of ten FEL beam lines. Various issues regarding machine layout and lattice, bunch compression, collimation, and the beam switch yard are discussed. Particular attention is given to collective effects. A demanding goal is to preserve both a low beam slice emittance and low slice energy spread during acceleration, bunch compression and distribution of the electron bunches into the array of FEL beamlines. Detailed studies of the effect of the electron beam microbunching caused by longitudinal space-charge forces and coherent synchrotron radiation (CSR) have been carried out and their results are presented

  1. Symmetric aluminum-wire arrays generate high-quality Z pinches at large array radii

    Energy Technology Data Exchange (ETDEWEB)

    Sanford, T.W.; Mock, R.C.; Spielman, R.B. [Sandia National Laboratories, P.O. Box 5800, Albuquerque, New Mexico 87185 (United States); Peterson, D.L. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545-0010 (United States); Mosher, D. [Naval Research Laboratory, Pulsed Power Physics Branch, Washington, DC 20375 (United States); Roderick, N.F. [University of New Mexico, Albuquerque, New Mexico 87131 (United States)

    1998-10-01

    A Saturn-accelerator study of annular, aluminum-wire array, Z-pinch implosions, in the calculated high-wire-number plasma-shell regime [Phys. Rev. Lett. {bold 77}, 5063 (1996)], shows that the radiated x-ray pulse width increases from about 4 nsec to about 7 nsec, when the radius of the array is increased from 8.75 to 20 mm at a fixed array mass of 0.6 mg. Eulerian radiation- magnetohydrodynamic code (E-RMHC) simulations in the r-z plane suggest that this pulse-width increase with radius is due to the faster growth of the shell thickness (that arises from a two-stage development in the magnetic Rayleigh{endash}Taylor instability) relative to the increase in the shell implosion velocity. Over the array radii explored, the measured peak total x-ray power of {approximately}40 TW and energy of {approximately}325 kJ show little change outside of a {plus_minus}15{percent} shot-to-shot fluctuation and are consistent with the E-RMHC simulations. Similarly, the measured peak {ital K}-shell (lines plus continuum) power of {approximately}8 TW and energy of {approximately}70 kJ show little change with radius. The minimal change in {ital K}-shell yield is in agreement with simple {ital K}-shell radiation scaling models that assume a fixed radial compression for all initial array radii. These results suggest that the improved uniformity provided by the large number of wires in the initial array reduces the disruptive effects of the Rayleigh{endash}Taylor instability observed in small-wire-number imploding loads. {copyright} {ital 1998 American Institute of Physics.}

  2. Human exposure standards in the frequency range 1 Hz To 100 kHz: the case for adoption of the IEEE standard.

    Science.gov (United States)

    Patrick Reilly, J

    2014-10-01

    Differences between IEEE C95 Standards (C95.6-2002 and C95.1-2005) in the low-frequency (1 Hz-100 kHz) and the ICNIRP-2010 guidelines appear across the frequency spectrum. Factors accounting for lack of convergence include: differences between the IEEE standards and the ICNIRP guidelines with respect to biological induction models, stated objectives, data trail from experimentally derived thresholds through physical and biological principles, selection and justification of safety/reduction factors, use of probability models, compliance standards for the limbs as distinct from the whole body, defined population categories, strategies for central nervous system protection below 20 Hz, and correspondence of environmental electric field limits with contact currents. This paper discusses these factors and makes the case for adoption of the limits in the IEEE standards.

  3. Development of a poly(dimethylacrylamide) based matrix material for solid phase high density peptide array synthesis employing a laser based material transfer

    International Nuclear Information System (INIS)

    Ridder, Barbara; Foertsch, Tobias C.; Welle, Alexander; Mattes, Daniela S.; Bojnicic-Kninski, Clemens M. von; Loeffler, Felix F.; Nesterov-Mueller, Alexander; Meier, Michael A.R.; Breitling, Frank

    2016-01-01

    Highlights: • New matrix material for peptide array synthesis from a ‘solid solvent’. • Resolution was increased with possible spot densities of up to 20.000 spots per cm"2. • The coupling depth and the effectiveness of washing steps analyzed by ToF-SIMS. • Adaptations and custom changes of the matrix material are possible. - Abstract: Poly(dimethylacrylamide) (PDMA) based matrix materials were developed for laser-based in situ solid phase peptide synthesis to produce high density arrays. In this specific array synthesis approach, amino acid derivatives are embedded into a matrix material, serving as a “solid” solvent material at room temperature. Then, a laser pulse transfers this mixture to the target position on a synthesis slide, where the peptide array is synthesized. Upon heating above the glass transition temperature of the matrix material, it softens, allowing diffusion of the amino acid derivatives to the synthesis surface and serving as a solvent for peptide bond formation. Here, we synthesized PDMA six-arm star polymers, offering the desired matrix material properties, using atom transfer radical polymerization. With the synthesized polymers as matrix material, we structured and synthesized arrays with combinatorial laser transfer. With densities of up to 20,000 peptide spots per cm"2, the resolution could be increased compared to the commercially available standard matrix material. Time-of-Flight Secondary Ion Mass Spectrometry experiments revealed the penetration behavior of an amino acid derivative into the prepared acceptor synthesis surface and the effectiveness of the washing protocols.

  4. Development of a poly(dimethylacrylamide) based matrix material for solid phase high density peptide array synthesis employing a laser based material transfer

    Energy Technology Data Exchange (ETDEWEB)

    Ridder, Barbara [Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe (Germany); Foertsch, Tobias C. [Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Welle, Alexander [Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Mattes, Daniela S. [Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe (Germany); Bojnicic-Kninski, Clemens M. von; Loeffler, Felix F.; Nesterov-Mueller, Alexander [Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Meier, Michael A.R., E-mail: m.a.r.meier@kit.edu [Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe (Germany); Breitling, Frank, E-mail: frank.breitling@kit.edu [Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)

    2016-12-15

    Highlights: • New matrix material for peptide array synthesis from a ‘solid solvent’. • Resolution was increased with possible spot densities of up to 20.000 spots per cm{sup 2}. • The coupling depth and the effectiveness of washing steps analyzed by ToF-SIMS. • Adaptations and custom changes of the matrix material are possible. - Abstract: Poly(dimethylacrylamide) (PDMA) based matrix materials were developed for laser-based in situ solid phase peptide synthesis to produce high density arrays. In this specific array synthesis approach, amino acid derivatives are embedded into a matrix material, serving as a “solid” solvent material at room temperature. Then, a laser pulse transfers this mixture to the target position on a synthesis slide, where the peptide array is synthesized. Upon heating above the glass transition temperature of the matrix material, it softens, allowing diffusion of the amino acid derivatives to the synthesis surface and serving as a solvent for peptide bond formation. Here, we synthesized PDMA six-arm star polymers, offering the desired matrix material properties, using atom transfer radical polymerization. With the synthesized polymers as matrix material, we structured and synthesized arrays with combinatorial laser transfer. With densities of up to 20,000 peptide spots per cm{sup 2}, the resolution could be increased compared to the commercially available standard matrix material. Time-of-Flight Secondary Ion Mass Spectrometry experiments revealed the penetration behavior of an amino acid derivative into the prepared acceptor synthesis surface and the effectiveness of the washing protocols.

  5. Managing digitally formatted diagnostic image data

    International Nuclear Information System (INIS)

    Templeton, A.W.; Dwyer, S.J.

    1985-01-01

    Diagnostic radiologists are very comfortable using analog radiographic film and interpreting its recorded images. To improve patient care, the radiologist has sought the finest quality radiographic film for use with the best radiographic imaging systems. The proper choice and use of x-ray tubes, generators, film-screen combinations, and contrast media has occupied the professional attention of the radiologist since the inception of radiology. Image quality can be significantly improved with digitally formatted diagnostic imaging systems by providing dynamic ranges in excess of those possible with analog x-ray films. In a CT scanner, the digital acquisition and reconstruction system can obtain a dynamic range (contrast resolution) of 10,000 to 1. Digital subtraction angiography systems achieve 10-bit dynamic ranges for each of the acquired television frames. Increases in the dynamic ranges of the various imaging modalities have been coupled with improved spatial resolution. A digitally formatted image is a two-dimensional, numerical array of discrete image elements. Each picture element is called a pixel. Each pixel has a discrete size. Figure 15.1 illustrates a digitally formatted image depicting the spatial resolution, array size, and quantization or numerical range of the pixel values. Currently, 512 x 512 image arrays are standard. Development of 1024 x 1024 digital arrays are underway. Significant improvements have also been achieved in the rates at which digital diagnostic imaging data can be acquired, manipulated, and archived

  6. Phased Array Ultrasonic Examination of Reactor Coolant System (Carbon Steel-to-CASS) Dissimilar Metal Weld Mockup Specimen

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, S. L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cinson, A. D. [US Nuclear Regulatory Commission (NRC), Washington, DC (United States); Diaz, A. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Anderson, M. T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-11-23

    In the summer of 2009, Pacific Northwest National Laboratory (PNNL) staff traveled to the Electric Power Research Institute (EPRI) NDE Center in Charlotte, North Carolina, to conduct phased-array ultrasonic testing on a large bore, reactor coolant pump nozzle-to-safe-end mockup. This mockup was fabricated by FlawTech, Inc. and the configuration originated from the Port St. Lucie nuclear power plant. These plants are Combustion Engineering-designed reactors. This mockup consists of a carbon steel elbow with stainless steel cladding joined to a cast austenitic stainless steel (CASS) safe-end with a dissimilar metal weld and is owned by Florida Power & Light. The objective of this study, and the data acquisition exercise held at the EPRI NDE Center, were focused on evaluating the capabilities of advanced, low-frequency phased-array ultrasonic testing (PA-UT) examination techniques for detection and characterization of implanted circumferential flaws and machined reflectors in a thick-section CASS dissimilar metal weld component. This work was limited to PA-UT assessments using 500 kHz and 800 kHz probes on circumferential flaws only, and evaluated detection and characterization of these flaws and machined reflectors from the CASS safe-end side only. All data were obtained using spatially encoded, manual scanning techniques. The effects of such factors as line-scan versus raster-scan examination approaches were evaluated, and PA-UT detection and characterization performance as a function of inspection frequency/wavelength, were also assessed. A comparative assessment of the data is provided, using length-sizing root-mean-square-error and position/localization results (flaw start/stop information) as the key criteria for flaw characterization performance. In addition, flaw signal-to-noise ratio was identified as the key criterion for detection performance.

  7. Recent achievements on the development of the HERSCHEL/PACS bolometer arrays

    International Nuclear Information System (INIS)

    Billot, N.; Agnese, P.; Boulade, O.; Cigna, C.; Doumayrou, E.; Horeau, B.; Lepennec, J.; Martignac, J.; Pornin, J.-L.; Reveret, V.; Rodriguez, L.; Sauvage, M.; Simoens, F.; Vigroux, L.

    2006-01-01

    A new type of bolometer arrays sensitive in the far Infrared and Submillimeter range has been developed and manufactured by CEA/LETI/SLIR since 1997. These arrays will be integrated in the PACS instrument (Photodetector Array Camera and Spectrometer) of ESA's Herschel Space Observatory (launch date 2007). The main innovations of CEA bolometers are their collective manufacturing technique (production of 3-side buttable 16x16 arrays) and their high mapping efficiency (large format detector and instantaneous Nyquist sampling). The measured NEP is 2.10 -16 W/Hz and the thermometric passband about 4-5Hz. In this article we describe CEA bolometers and present the results obtained during the last test campaign

  8. Recent achievements on the development of the HERSCHEL/PACS bolometer arrays

    Energy Technology Data Exchange (ETDEWEB)

    Billot, N. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France)]. E-mail: nbillot@cea.fr; Agnese, P. [CEA/LETI Grenoble, 17 Avenue des Martyrs, 38054 Grenoble (France); Boulade, O. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Cigna, C. [CEA/LETI Grenoble, 17 Avenue des Martyrs, 38054 Grenoble (France); Doumayrou, E. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Horeau, B. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Lepennec, J. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Martignac, J. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Pornin, J.-L. [CEA/LETI Grenoble, 17 Avenue des Martyrs, 38054 Grenoble (France); Reveret, V. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Rodriguez, L. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Sauvage, M. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Simoens, F. [CEA/LETI Grenoble, 17 Avenue des Martyrs, 38054 Grenoble (France); Vigroux, L. [CEA/Saclay/SAp, UMR CEA/CNRS/UP7 Laboratoire AIM, Bat. 709, l' Orme des merisiers, 91191 Gif-sur-Yvette (France); Institut d' Astrophysique de Paris, 75014 Paris (France)

    2006-11-01

    A new type of bolometer arrays sensitive in the far Infrared and Submillimeter range has been developed and manufactured by CEA/LETI/SLIR since 1997. These arrays will be integrated in the PACS instrument (Photodetector Array Camera and Spectrometer) of ESA's Herschel Space Observatory (launch date 2007). The main innovations of CEA bolometers are their collective manufacturing technique (production of 3-side buttable 16x16 arrays) and their high mapping efficiency (large format detector and instantaneous Nyquist sampling). The measured NEP is 2.10{sup -16}W/Hz and the thermometric passband about 4-5Hz. In this article we describe CEA bolometers and present the results obtained during the last test campaign.

  9. Intracranial inertial cavitation threshold and thermal ablation lesion creation using MRI-guided 220-kHz focused ultrasound surgery: preclinical investigation.

    Science.gov (United States)

    Xu, Zhiyuan; Carlson, Carissa; Snell, John; Eames, Matt; Hananel, Arik; Lopes, M Beatriz; Raghavan, Prashant; Lee, Cheng-Chia; Yen, Chun-Po; Schlesinger, David; Kassell, Neal F; Aubry, Jean-Francois; Sheehan, Jason

    2015-01-01

    In biological tissues, it is known that the creation of gas bubbles (cavitation) during ultrasound exposure is more likely to occur at lower rather than higher frequencies. Upon collapsing, such bubbles can induce hemorrhage. Thus, acoustic inertial cavitation secondary to a 220-kHz MRI-guided focused ultrasound (MRgFUS) surgery is a serious safety issue, and animal studies are mandatory for laying the groundwork for the use of low-frequency systems in future clinical trials. The authors investigate here the in vivo potential thresholds of MRgFUS-induced inertial cavitation and MRgFUS-induced thermal coagulation using MRI, acoustic spectroscopy, and histology. Ten female piglets that had undergone a craniectomy were sonicated using a 220-kHz transcranial MRgFUS system over an acoustic energy range of 5600-14,000 J. For each piglet, a long-duration sonication (40-second duration) was performed on the right thalamus, and a short sonication (20-second duration) was performed on the left thalamus. An acoustic power range of 140-300 W was used for long-duration sonications and 300-700 W for short-duration sonications. Signals collected by 2 passive cavitation detectors were stored in memory during each sonication, and any subsequent cavitation activity was integrated within the bandwidth of the detectors. Real-time 2D MR thermometry was performed during the sonications. T1-weighted, T2-weighted, gradient-recalled echo, and diffusion-weighted imaging MRI was performed after treatment to assess the lesions. The piglets were killed immediately after the last series of posttreatment MR images were obtained. Their brains were harvested, and histological examinations were then performed to further evaluate the lesions. Two types of lesions were induced: thermal ablation lesions, as evidenced by an acute ischemic infarction on MRI and histology, and hemorrhagic lesions, associated with inertial cavitation. Passive cavitation signals exhibited 3 main patterns identified as

  10. THE KILOPARSEC-SCALE STAR FORMATION LAW AT REDSHIFT 4: WIDESPREAD, HIGHLY EFFICIENT STAR FORMATION IN THE DUST-OBSCURED STARBURST GALAXY GN20

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, J. A. [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Riechers, D. [Department of Astronomy, Cornell University, Ithaca, New York, NY 14853 (United States); Decarli, R.; Walter, F. [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Carilli, C. L. [National Radio Astronomy Observatory, P.O. Box 0, Socorro, NM 87801-0387 (United States); Daddi, E. [CEA, Laboratoire AIM-CNRS-Université Paris Diderot, Irfu/SAp, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Dannerbauer, H., E-mail: jhodge@nrao.edu [Universität Wien, Institut für Astrophysik, Türkenschanzstraße 17, 1180 Wien (Austria)

    2015-01-01

    We present high-resolution observations of the 880 μm (rest-frame FIR) continuum emission in the z = 4.05 submillimeter galaxy GN20 from the IRAM Plateau de Bure Interferometer (PdBI). These data resolve the obscured star formation (SF) in this unlensed galaxy on scales of 0.''3 × 0.''2 (∼2.1 × 1.3 kpc). The observations reveal a bright (16 ± 1 mJy) dusty starburst centered on the cold molecular gas reservoir and showing a bar-like extension along the major axis. The striking anti-correlation with the Hubble Space Telescope/Wide Field Camera 3 imaging suggests that the copious dust surrounding the starburst heavily obscures the rest-frame UV/optical emission. A comparison with 1.2 mm PdBI continuum data reveals no evidence for variations in the dust properties across the source within the uncertainties, consistent with extended SF, and the peak star formation rate surface density (119 ± 8 M {sub ☉} yr{sup –1} kpc{sup –2}) implies that the SF in GN20 remains sub-Eddington on scales down to 3 kpc{sup 2}. We find that the SF efficiency (SFE) is highest in the central regions of GN20, leading to a resolved SF law with a power-law slope of Σ{sub SFR} ∼ Σ{sub H{sub 2}{sup 2.1±1.0}}, and that GN20 lies above the sequence of normal star-forming disks, implying that the dispersion in the SF law is not due solely to morphology or choice of conversion factor. These data extend previous evidence for a fixed SFE per free-fall time to include the star-forming medium on ∼kiloparsec scales in a galaxy 12 Gyr ago.

  11. A general melt-injection-decomposition route to oriented metal oxide nanowire arrays

    Energy Technology Data Exchange (ETDEWEB)

    Han, Dongqiang; Zhang, Xinwei; Hua, Zhenghe; Yang, Shaoguang, E-mail: sgyang@nju.edu.cn

    2016-12-30

    Highlights: • A general melt-injection-decomposition (MID) route is proposed for the fabrication of oriented metal oxide nanowire arrays. • Four kinds of metal oxide (CuO, Mn{sub 2}O{sub 3}, Co{sub 3}O{sub 4} and Cr{sub 2}O{sub 3}) nanowire arrays have been realized as examples through the developed MID route. • The mechanism of the developed MID route is discussed using Thermogravimetry and Differential Thermal Analysis technique. • The MID route is a versatile, simple, facile and effective way to prepare different kinds of oriented metal oxide nanowire arrays in the future. - Abstract: In this manuscript, a general melt-injection-decomposition (MID) route has been proposed and realized for the fabrication of oriented metal oxide nanowire arrays. Nitrate was used as the starting materials, which was injected into the nanopores of the anodic aluminum oxide (AAO) membrane through the capillarity action in its liquid state. At higher temperature, the nitrate decomposed into corresponding metal oxide within the nanopores of the AAO membrane. Oriented metal oxide nanowire arrays were formed within the AAO membrane as a result of the confinement of the nanopores. Four kinds of metal oxide (CuO, Mn{sub 2}O{sub 3}, Co{sub 3}O{sub 4} and Cr{sub 2}O{sub 3}) nanowire arrays are presented here as examples fabricated by this newly developed process. X-ray diffraction, scanning electron microscopy and transmission electron microscopy studies showed clear evidence of the formations of the oriented metal oxide nanowire arrays. Formation mechanism of the metal oxide nanowire arrays is discussed based on the Thermogravimetry and Differential Thermal Analysis measurement results.

  12. A contribution from dielectric analysis to the study of the formation of multi-wall carbon nanotubes percolated networks in epoxy resin under an electric field

    International Nuclear Information System (INIS)

    Risi, Celso L.S.; Hattenhauer, Irineu; Ramos, Airton; Coelho, Luiz A.F.; Pezzin, Sérgio H.

    2015-01-01

    The formation of percolation networks in epoxy matrix nanocomposites reinforced with multi-wall carbon nanotubes (MWNT) during the curing process, at different MWNT contents, was studied by using a parallel plate cell subjected to a 300 V/cm AC electric field at 1 kHz. The percolation was verified by the electrical current output measured during and after the resin curing. The behavior of electric dipoles was characterized by impedance spectroscopy and followed the Debye first order dispersion model, by which an average relaxation time of 6.0 × 10 −4 s and a cut-off frequency of 1.7 kHz were experimentally found. By applying the theory of percolation, a critical probability, p c , equal to 0.038 vol% and an exponent of conductivity of 2.0 were found. Both aligned and random samples showed dipole relaxation times typical of interfacial and/or charge-hopping polarization, while the permittivity exhibited an exponential decrease with frequency. This behavior can be related to the increased ability to trap electrical charges due to the formation of the carbon nanotubes network. Optical and electron microscopies confirm the theoretical prediction that the application of an electric field during cure helps the process of MWNT debundling in epoxy resin. - Highlights: • We report the formation of percolating networks of MWNTs under AC electric field. • MWNT/epoxy dielectric properties were measured by impedance spectroscopy. • Lower percolation thresholds were obtained for composites with aligned CNTs. • Application of AC electric field helps the debundling of CNTs. • CNT/Epoxy with percolated networks presents interfacial and hopping polarizations

  13. Two siblings with alternate unbalanced recombinants derived from a large cryptic maternal pericentric inversion of chromosome 20.

    Science.gov (United States)

    Descipio, Cheryl; Morrissette, Jennifer D; Conlin, Laura K; Clark, Dinah; Kaur, Maninder; Coplan, James; Riethman, Harold; Spinner, Nancy B; Krantz, Ian D

    2010-02-01

    Two brothers, with dissimilar clinical features, were each found to have different abnormalities of chromosome 20 by subtelomere fluorescence in situ hybridization (FISH). The proband had deletion of 20p subtelomere and duplication of 20q subtelomere, while his brother was found to have a duplication of 20p subtelomere and deletion of 20q subtelomere. Parental cytogenetic studies were initially thought to be normal, both by G-banding and by subtelomere FISH analysis. Since chromosome 20 is a metacentric chromosome and an inversion was suspected, we used anchored FISH to assist in identifying a possible inversion. This approach employed concomitant hybridization of a FISH probe to the short (p) arm of chromosome 20 with the 20q subtelomere probe. We identified a cytogenetically non-visible, mosaic pericentric inversion of one of the maternal chromosome 20 homologs, providing a mechanistic explanation for the chromosomal abnormalities present in these brothers. Array comparative genomic hybridization (CGH) with both a custom-made BAC and cosmid-based subtelomere specific array (TEL array) and a commercially available SNP-based array confirmed and further characterized these rearrangements, identifying this as the largest pericentric inversion of chromosome 20 described to date. TEL array data indicate that the 20p breakpoint is defined by BAC RP11-978M13, approximately 900 kb from the pter; SNP array data reveal this breakpoint to occur within BAC RP11-978M13. The 20q breakpoint is defined by BAC RP11-93B14, approximately 1.7 Mb from the qter, by TEL array; SNP array data refine this breakpoint to within a gap between BACs on the TEL array (i.e., between RP11-93B14 and proximal BAC RP11-765G16). Copyright 2010 Wiley-Liss, Inc.

  14. 5 kW, 5 kHz class-A inverter for DC accelerator in CAT, Indore (Paper No. CP 19)

    International Nuclear Information System (INIS)

    Thakurta, A.C.; Krishnaswamy, B.

    1990-01-01

    The 5 kHz, 5kW inverter described here is meant for energizing a high voltage transformer feeding a 2-stage Cockcroft-Walton multipliers with 100 kVDC output. This output is to be used as the acceleration voltage in DC accelerator at CAT, Indore. The load is expected to draw few tens of mA current, which means that with the values of the capacitors readily available with voltage ratings of 50 kVDC and above, there will be considerable drop in multiplier output voltage and ripple voltage also will be quite high, if one goes in for line-frequency operation. The frequency of 5 kHz suggests a good compromise between low ripple and DC drop, and the availability of devices switching at high frequency and handling kilowatts of power. The class A type of inverter which has reasonably good load regulation and tolerance to reactive loads was deemed suitable for generating this 5 kHz AC voltage. The DC voltage needed for the inverter was obtained from a phase-controlled supply which was put in closed loop to achieve regulation with respect to line and load variation. The output could be varied with external setting of a reference voltage. (author). 3 figs

  15. Wide-range frequency selectivity in an acoustic sensor fabricated using a microbeam array with non-uniform thickness

    International Nuclear Information System (INIS)

    Shintaku, Hirofumi; Kotera, Hidetoshi; Kobayashi, Takayuki; Zusho, Kazuki; Kawano, Satoyuki

    2013-01-01

    In this study, we have demonstrated the fabrication of a microbeam array (MBA) with various thicknesses and investigated the suitability it for an acoustic sensor with wide-range frequency selectivity. For this, an MBA composed of 64 beams, with thicknesses varying from 2.99–142 µm, was fabricated by using single gray-scale lithography and a thick negative photoresist. The vibration of the beams in air was measured using a laser Doppler vibrometer; the resonant frequencies of the beams were measured to be from 11.5 to 290 kHz. Lastly, the frequency range of the MBA with non-uniform thickness was 10.9 times that of the MBA with uniform thickness. (paper)

  16. Experimental simulation of satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds

    Directory of Open Access Journals (Sweden)

    M. Füllekrug

    2011-01-01

    Full Text Available Relativistic electron beams above thunderclouds emit 100 kHz radio waves which illuminate the Earth's atmosphere and near-Earth space. This contribution aims to clarify the physical processes which are relevant for the spatial spreading of the radio wave energy below and above the ionosphere and thereby enables an experimental simulation of satellite observations of 100 kHz radio waves from relativistic electron beams above thunderclouds. The simulation uses the DEMETER satellite which observes 100 kHz radio waves from fifty terrestrial Long Range Aid to Navigation (LORAN transmitters. Their mean luminosity patch in the plasmasphere is a circular area with a radius of 300 km and a power density of 22 μW/Hz as observed at 660 km height above the ground. The luminosity patches exhibit a southward displacement of 450 km with respect to the locations of the LORAN transmitters. The displacement is reduced to 150 km when an upward propagation of the radio waves along the geomagnetic field line is assumed. This residual displacement indicates that the radio waves undergo 150 km sub-ionospheric propagation prior to entering a magnetospheric duct and escaping into near-Earth space. The residual displacement at low (L < 2.14 and high (L > 2.14 geomagnetic latitudes ranges from 100 km to 200 km which suggests that the smaller inclination of the geomagnetic field lines at low latitudes helps to trap the radio waves and to keep them in the magnetospheric duct. Diffuse luminosity areas are observed northward of the magnetic conjugate locations of LORAN transmitters at extremely low geomagnetic latitudes (L < 1.36 in Southeast Asia. This result suggests that the propagation along the geomagnetic field lines results in a spatial spreading of the radio wave energy over distances of 1 Mm. The summative assessment of the electric field intensities measured in space show that nadir observations of terrestrial 100 kHz radio waves, e.g., from

  17. Overexposure effects of a 1-kHz tone on the distortion product otoacoustic emission in humans

    DEFF Research Database (Denmark)

    Reuter, Karen; Ordoñez, Rodrigo Pizarro; Hammershøi, Dorte

    2007-01-01

    The effects of overexposure on the properties of distortion product otoacoustic emissions (DPOAEs) are investigated. In total, 39 normal-hearing humans were monaurally exposed to a 1-kHz tone lasting for 3 min at an equivalent threshold sound-pressure level of 105.5 dB. The effects of overexposure...

  18. Surface Modifications of Support Partitions for Stabilizing Biomimetic Membrane Arrays

    DEFF Research Database (Denmark)

    Perry, Mark; Hansen, Jesper Schmidt; Jensen, Karin Bagger Stibius

    2011-01-01

    with a high signal-to-noise (s/n) ratio. We demonstratesd this by reconstituting gA and α-hemolysin (α-HL) into BLM arrays. The improvement in membrane array lifetime and s/n ratio demonstrates that surface plasma polymerization of the supporting partition can be used to increase the stability of biomimetic......Black lipid membrane (BLM) formation across apertures in an ethylene tetra-fluoroethylene (ETFE) partition separating two aqueous compartments is an established technique for the creation of biomimetic membranes. Recently multi-aperture BLM arrays have attracted interest and in order to increase...... BLM array stability we studied the effect of covalently modifying the partition substrate using surface plasma polymerization with hydrophobic n-hexene, 1-decene and hexamethyldisiloxane (HMDSO) as modification groups. Average lifetimes across singlesided HMDSO modified partitions or using 1-decene...

  19. IDENTIFIKASI PROFIL DASAR LAUT MENGGUNAKAN INSTRUMEN SIDE SCAN SONAR DENGAN METODE BEAM PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY

    Directory of Open Access Journals (Sweden)

    Muhammad Zainuddin Lubis

    2017-05-01

    Full Text Available Laut Punggur merupakan laut yang terletak di Batam, Kepulauan Riau yang mempunyai beragam habitat objek,dan bentuk struktur bawah laut yang memiliki dinamika laut yang sangat tinggi. Side scan sonar (SSS merupakan instrumen pengembangan sistem sonar yang mampu menunjukkan dalam gambar dua dimensional permukaan dasar laut dengan kondisi kontur, topografi, dan target secara bersamaan. Metode Beam Pattern Discrete-Equi-Spaced Unshaded Line Array digunakan untuk menghitung beam pattern dua dimensi yang tergantung pada sudut dari gelombang suara yang masuk dari sumbu array yang diterima tergantung pada sudut di mana sinar suara pada array. Penelitian ini dilakukan pada Desember 2016 di laut Punggur,Batam, Kepulauan Riau-Indonesia, dengan koordinat 104 ° 08,7102 E dan 1° 03,2448 N sampai 1 ° 03.3977 N dan 104 ° 08,8133 E, menggunakan instrumen Side Scan Sonar C-Max CM2 Tow fish dengan frekuensi 325 kHz. Hasil yang diperoleh dari perekaman terdapat 7 target, dan Beam pattern dari metode Beam Discrete-Equi-Spaced Unshaded Line Array target 4 memiliki nilai tertinggi pada directivity Pattern yaitu 21.08 dB. Hasil model beam pattern ini memiliki nilai pusat pada incidence angle (o terhadap Directivity pattern (dB tidak berada di nilai 0 ataupun pada pusat beam pattern yang dihasilkan pada target 6 dengan nilai incident angle -1.5 o dan 1.5o mengalami penurunan hingga -40 dB. Karakteristik sedimen dasar perairan di laut punggur ditemukan lebih banyak pasir. Hasil metode Beam Discrete-Equi-Spaced Unshaded Line Array ditemukan bangkai kapal tenggelam.Kata Kunci: Side Scan Sonar, Beam Pattern Discrete-Equi-Spaced Unshaded Line Array, Incidence angle, Directivity pattern IDENTIFICATION OF SEABED PROFILE USING SIDE SCAN SONAR INSTRUMENT WITH PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY METHODRiau Islands is an island that has a variety of habitat objects, and forms of submarine structures that have a very high ocean dynamics, Punggur Sea is the sea

  20. Behavioral Correlates of 50-kHz Ultrasonic Vocalizations in Rats: Progressive Operant Discrimination Learning Reduces Frequency Modulation and Increases Overall Amplitude

    Directory of Open Access Journals (Sweden)

    Shoko Yuki

    2014-11-01

    Full Text Available Ultrasonic vocalizations (USVs in rats are thought to contain ecological signals reflecting emotional states. These USVs are centered on 50-kHz, and frequency modulation (FM is hypothesized to indicate positive emotion; however, results from recent studies are inconsistent with this hypothesis. We suspected that such inconsistencies might result from ambiguity in defining frequency modulation, and problems with acoustic analyses and behavioral protocols. We addressed these problems by applying quantitative methods for USV analyses and using a food reward operant paradigm. Our results revealed that frequency modulation varied according to the degree of positive outcomes, but the direction of change was opposite to what had been observed in previous studies. The FM in 50-kHz USVs decreased as animals learned the task and obtained more reinforcement, while USV amplitude increased as learning progressed. To reconcile these results with those from prior studies, we suggest that FM in 50-kHz USVs should be taken as an index of reward prediction errors, and USV amplitude should be considered as an index of positive emotion.

  1. 360/degree/ digital phase detector with 100-kHz bandwidth

    International Nuclear Information System (INIS)

    Reid, D.W.; Riggin, D.; Fazio, M.V.; Biddle, R.S.; Patton, R.D.; Jackson, H.A.

    1981-01-01

    The general availability of digital circuit components with propagation delay times of a few nanoseconds makes a digital phase detector with good bandwidth feasible. Such a circuit has a distinct advantage over its analog counterpart because of its linearity over a wide range of phase shift. A description is given of a phase detector that is being built at Los Alamos National Laboratory for the Fusion Materials Irradiation Test (FMIT) project. The specifications are 100-kHz bandwidth, linearity of /plus or minus/1/degree/ over /plus or minus/180/degree/ of phase shift, and 0.66/degree/ resolution. To date, the circuit has achieved the bandwidth and resolution. The linearity is approximately /plus or minus/3/degree/ over /plus or minus/180/degree/ phase shift. 3 refs

  2. A Wavelet-Modified ESPRIT Hybrid Method for Assessment of Spectral Components from 0 to 150 kHz

    Directory of Open Access Journals (Sweden)

    Luisa Alfieri

    2017-01-01

    Full Text Available Waveform distortions are an important issue in distribution systems. In particular, the assessment of very wide spectra, that include also components in the 2–150 kHz range, has recently become an issue of great interest. This is due to the increasing presence of high-spectral emission devices like end-user devices and distributed generation systems. This study proposed a new sliding-window wavelet-modified estimation of signal parameters by rotational invariance technique (ESPRIT method, particularly suitable for the spectral analysis of waveforms that have very wide spectra. The method is very accurate and requires reduced computational effort. It can be applied successfully to detect spectral components in the range of 0–150 kHz introduced both by distributed power plants, such as wind and photovoltaic generation systems, and by end-user equipment connected to grids through static converters, such as fluorescent lamps.

  3. Field Emission of ITO-Coated Vertically Aligned Nanowire Array.

    KAUST Repository

    Lee, Changhwa

    2010-04-29

    An indium tin oxide (ITO)-coated vertically aligned nanowire array is fabricated, and the field emission characteristics of the nanowire array are investigated. An array of vertically aligned nanowires is considered an ideal structure for a field emitter because of its parallel orientation to the applied electric field. In this letter, a vertically aligned nanowire array is fabricated by modified conventional UV lithography and coated with 0.1-μm-thick ITO. The turn-on electric field intensity is about 2.0 V/μm, and the field enhancement factor, β, is approximately 3,078 when the gap for field emission is 0.6 μm, as measured with a nanomanipulator in a scanning electron microscope.

  4. Field Emission of ITO-Coated Vertically Aligned Nanowire Array.

    KAUST Repository

    Lee, Changhwa; Lee, Seokwoo; Lee, Seung S

    2010-01-01

    An indium tin oxide (ITO)-coated vertically aligned nanowire array is fabricated, and the field emission characteristics of the nanowire array are investigated. An array of vertically aligned nanowires is considered an ideal structure for a field emitter because of its parallel orientation to the applied electric field. In this letter, a vertically aligned nanowire array is fabricated by modified conventional UV lithography and coated with 0.1-μm-thick ITO. The turn-on electric field intensity is about 2.0 V/μm, and the field enhancement factor, β, is approximately 3,078 when the gap for field emission is 0.6 μm, as measured with a nanomanipulator in a scanning electron microscope.

  5. Upgrading a high-throughput spectrometer for high-frequency (<400 kHz) measurements

    Science.gov (United States)

    Nishizawa, T.; Nornberg, M. D.; Den Hartog, D. J.; Craig, D.

    2016-11-01

    The upgraded spectrometer used for charge exchange recombination spectroscopy on the Madison Symmetric Torus resolves emission fluctuations up to 400 kHz. The transimpedance amplifier's cutoff frequency was increased based upon simulations comparing the change in the measured photon counts for time-dynamic signals. We modeled each signal-processing stage of the diagnostic and scanned the filtering frequency to quantify the uncertainty in the photon counting rate. This modeling showed that uncertainties can be calculated based on assuming each amplification stage is a Poisson process and by calibrating the photon counting rate with a DC light source to address additional variation.

  6. Upgrading a high-throughput spectrometer for high-frequency (<400 kHz) measurements

    International Nuclear Information System (INIS)

    Nishizawa, T.; Nornberg, M. D.; Den Hartog, D. J.; Craig, D.

    2016-01-01

    The upgraded spectrometer used for charge exchange recombination spectroscopy on the Madison Symmetric Torus resolves emission fluctuations up to 400 kHz. The transimpedance amplifier’s cutoff frequency was increased based upon simulations comparing the change in the measured photon counts for time-dynamic signals. We modeled each signal-processing stage of the diagnostic and scanned the filtering frequency to quantify the uncertainty in the photon counting rate. This modeling showed that uncertainties can be calculated based on assuming each amplification stage is a Poisson process and by calibrating the photon counting rate with a DC light source to address additional variation.

  7. Upgrading a high-throughput spectrometer for high-frequency (<400 kHz) measurements

    Energy Technology Data Exchange (ETDEWEB)

    Nishizawa, T., E-mail: nishizawa@wisc.edu; Nornberg, M. D.; Den Hartog, D. J. [University of Wisconsin–Madison, Madison, Wisconsin 53706 (United States); Craig, D. [Wheaton College, Wheaton, Illinois 60187 (United States)

    2016-11-15

    The upgraded spectrometer used for charge exchange recombination spectroscopy on the Madison Symmetric Torus resolves emission fluctuations up to 400 kHz. The transimpedance amplifier’s cutoff frequency was increased based upon simulations comparing the change in the measured photon counts for time-dynamic signals. We modeled each signal-processing stage of the diagnostic and scanned the filtering frequency to quantify the uncertainty in the photon counting rate. This modeling showed that uncertainties can be calculated based on assuming each amplification stage is a Poisson process and by calibrating the photon counting rate with a DC light source to address additional variation.

  8. Fabrication of plasmonic cavity arrays for SERS analysis

    Science.gov (United States)

    Li, Ning; Feng, Lei; Teng, Fei; Lu, Nan

    2017-05-01

    The plasmonic cavity arrays are ideal substrates for surface enhanced Raman scattering analysis because they can provide hot spots with large volume for analyte molecules. The large area increases the probability to make more analyte molecules on hot spots and leads to a high reproducibility. Therefore, to develop a simple method for creating cavity arrays is important. Herein, we demonstrate how to fabricate a V and W shape cavity arrays by a simple method based on self-assembly. Briefly, the V and W shape cavity arrays are respectively fabricated by taking KOH etching on a nanohole and a nanoring array patterned silicon (Si) slides. The nanohole array is generated by taking a reactive ion etching on a Si slide assembled with monolayer of polystyrene (PS) spheres. The nanoring array is generated by taking a reactive ion etching on a Si slide covered with a monolayer of octadecyltrichlorosilane before self-assembling PS spheres. Both plasmonic V and W cavity arrays can provide large hot area, which increases the probability for analyte molecules to deposit on the hot spots. Taking 4-Mercaptopyridine as analyte probe, the enhancement factor can reach 2.99 × 105 and 9.97 × 105 for plasmonic V cavity and W cavity array, respectively. The relative standard deviations of the plasmonic V and W cavity arrays are 6.5% and 10.2% respectively according to the spectra collected on 20 random spots.

  9. Volumetric display using a roof mirror grid array

    Science.gov (United States)

    Miyazaki, Daisuke; Hirano, Noboru; Maeda, Yuuki; Ohno, Keisuke; Maekawa, Satoshi

    2010-02-01

    A volumetric display system using a roof mirror grid array (RMGA) is proposed. The RMGA consists of a two-dimensional array of dihedral corner reflectors and forms a real image at a plane-symmetric position. A two-dimensional image formed with a RMGA is moved at thigh speed by a mirror scanner. Cross-sectional images of a three-dimensional object are displayed in accordance with the position of the image plane. A volumetric image can be observed as a stack of the cross-sectional images by high-speed scanning. Image formation by a RMGA is free from aberrations. Moreover, a compact optical system can be constructed because a RMGA doesn't have a focal length. An experimental volumetric display system using a galvanometer mirror and a digital micromirror device was constructed. The formation of a three-dimensional image consisting of 1024 × 768 × 400 voxels is confirmed by the experimental system.

  10. Progress report on the use of hybrid silicon pin diode arrays in high energy physics

    International Nuclear Information System (INIS)

    Shapiro, S.L.; Jernigan, J.G.; Arens, J.F.

    1990-05-01

    We report on the successful effort to develop hybrid PIN diode arrays and to demonstrate their potential as components of vertex detectors. Hybrid pixel arrays have been fabricated by the Hughes Aircraft Co. by bump-bonding readout chips developed by Hughes to an array of PIN diodes manufactured by Micron Semiconductor Inc. These hybrid pixel arrays were constructed in two configurations. One array format has 10 x 64 pixels, each 120 μm square; and the other format has 256 x 156 pixels, each 30 μm square. In both cases, the thickness of the PIN diode layer is 300 μm. Measurements of detector performance show that excellent position resolution can be achieved by interpolation. By determining the centroid of the charge cloud which spreads charge into a number of neighboring pixels, a spatial resolution of a few microns has been attained. The noise has been measured to be about 300 electrons (rms) at room temperature, as expected from KTC and dark current considerations, yielding a signal-to-noise ratio of about 100 for minimum ionizing particles. 4 refs., 17 figs

  11. Stochastic model explains formation of cell arrays on H/O-diamond patterns

    Czech Academy of Sciences Publication Activity Database

    Ukraintsev, Egor; Brož, A.; Hubálek Kalbáčová, M.; Kromka, Alexander; Rezek, Bohuslav

    2015-01-01

    Roč. 10, č. 4 (2015), "041006-1"-"041006-9" ISSN 1934-8630 R&D Projects: GA ČR GA15-01687S Institutional support: RVO:68378271 Keywords : cell migration * biofilm array * diamond surface * stochastic simulations Subject RIV: BO - Biophysics Impact factor: 2.105, year: 2015

  12. The signature of the first stars in atomic hydrogen at redshift 20.

    Science.gov (United States)

    Visbal, Eli; Barkana, Rennan; Fialkov, Anastasia; Tseliakhovich, Dmitriy; Hirata, Christopher M

    2012-07-05

    Dark and baryonic matter moved at different velocities in the early Universe, which strongly suppressed star formation in some regions. This was estimated to imprint a large-scale fluctuation signal of about two millikelvin in the 21-centimetre spectral line of atomic hydrogen associated with stars at a redshift of 20, although this estimate ignored the critical contribution of gas heating due to X-rays and major enhancements of the suppression. A large velocity difference reduces the abundance of haloes and requires the first stars to form in haloes of about a million solar masses, substantially greater than previously expected. Here we report a simulation of the distribution of the first stars at redshift 20 (cosmic age of around 180 million years), incorporating all these ingredients within a 400-megaparsec box. We find that the 21-centimetre hydrogen signature of these stars is an enhanced (ten millikelvin) fluctuation signal on the hundred-megaparsec scale, characterized by a flat power spectrum with prominent baryon acoustic oscillations. The required sensitivity to see this signal is achievable with an integration time of a thousand hours with an instrument like the Murchison Wide-field Array or the Low Frequency Array but designed to operate in the range of 50-100 megahertz.

  13. Surface plasmon enhanced quantum transport in a hybrid metal nanoparticle array

    International Nuclear Information System (INIS)

    Sun, Lin; Nan, Yali; Xu, Shang; Zhang, Sishi; Han, Min

    2014-01-01

    Hybrid Pd–Ag nanoparticle arrays composed of randomly distributed Pd nanoparticles in dense packing and a small number of dispersed Ag nanoparticles were fabricated with controlled coverage. Photo-enhanced conductance was observed in the nanoparticle arrays. Largest enhancement, which can be higher than 20 folds, was obtained with 450 nm light illumination. This wavelength was found to correlate with the surface plasmon resonance of the Ag nanoparticles. Electron transport measurements showed there were significant Coulomb blockade in the nanoparticle arrays and the blockade could be overcome with the surface plasmon enhanced local field of Ag nanoparticles induced by light illumination. - Highlights: • We study photo-enhanced electron conductance of a hybrid Pd–Ag nanoparticle array. • The light-induced conductance enhancement is as high as 20 folds at 10 K. • The enhancement is correlate with the surface plasmon resonance of Ag nanoparticles. • Coulomb blockades is overcome with the surface plasmon enhanced local field

  14. Design of Hybrid Nanostructural Arrays to Manipulate SERS-Active Substrates by Nanosphere Lithography.

    Science.gov (United States)

    Zhao, Xiaoyu; Wen, Jiahong; Zhang, Mengning; Wang, Dunhui; Wang, Yaxin; Chen, Lei; Zhang, Yongjun; Yang, Jinghai; Du, Youwei

    2017-03-01

    An easy-handling and low-cost method is utilized to controllably fabricate nanopattern arrays as the surface-enhanced Raman scattering (SERS) active substrates with high density of SERS-active areas (hot spots). A hybrid silver array of nanocaps and nanotriangles are prepared by combining magnetron sputtering and plasma etching. By adjusting the etching time of polystyrene (PS) colloid spheres array in silver nanobowls, the morphology of the arrays can be easily manipulated to control the formation and distribution of hot spots. The experimental results show that the hybrid nanostructural arrays have large enhancement factor, which is estimated to be seven times larger than that in the array of nanocaps and three times larger than that in the array of nanorings and nanoparticles. According to the results of finite-difference time-domain simulation, the excellent SERS performance of this array is ascribed to the high density of hot spots and enhanced electromagnetic field.

  15. Formation of a silicon micropore array of a two-dimension electron multiplier by photo electrochemical etching

    International Nuclear Information System (INIS)

    Gao Yanjun; Duanmu Qingduo; Wang Guozheng; Li Ye; Tian Jingquan

    2009-01-01

    A semiconductor PEC etching method is applied to fabricate the n-type silicon deep micropore channel array. In this method, it is important to arrange the direction of the micropore array along the crystal orientation of the Si substrate. Otherwise, serious lateral erosion will happen. The etching process is also relative to the light intensity and HF concentration. 5% HF concentration and 10-15 cm distance between the light source and the silicon wafer are demonstrated to be the best in our experiments. The n-type silicon deep micropore channel array with aperture of 3 μm and aspect ratio of 40-60, whose inner walls are smooth, is finally obtained.

  16. Joint formation of dissimilar steels in pressure welding with superposition of ultrasonic oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Surovtsev, A P; Golovanenko, S A; Sukhanov, V E; Kazantsev, V F

    1983-12-01

    Investigation results of kinetics and quality of carbon steel joints with the steel 12Kh18N10T, obtained by pressure welding with superposition of ultrasonic oscillations with the frequency 16.5-18.0 kHz are given. The effect of ultrasonic oscillations on the process of physical contact development of the surfaces welded, formation of microstructure and impact viscosity of the compound, is shown.

  17. Enhanced lubricant film formation through micro-dimpled hard-on-hard artificial hip joint: An in-situ observation of dimple shape effects.

    Science.gov (United States)

    Choudhury, Dipankar; Rebenda, David; Sasaki, Shinya; Hekrle, Pavel; Vrbka, Martin; Zou, Min

    2018-05-01

    This study evaluates the impact of dimple shapes on lubricant film formation in artificial hip joints. Micro-dimples with 20-50 µm lateral size and 1 ± 0.2 µm depths were fabricated on CrCoMo hip joint femoral heads using a picosecond laser. Tribological studies were performed using a pendulum hip joint simulator to apply continuous swing flexion-extension motions. The results revealed a significantly enhanced lubricant film thickness (≥ 500 nm) with micro-dimpled prosthesis heads at equilibrium position after the lubricant film has fully developed. The average lubricant film thickness of dimpled prostheses with square- and triangular-shaped dimple arrays over time is about 3.5 that of the non-dimpled prosthesis (204 nm). Remarkably, the prosthesis with square-shaped dimple arrays showed a very fast lubricant film formation reaching their peak values within 0.5 s of pendulum movement, followed by prosthesis with triangular-shaped dimple arrays with a transition period of 42.4 s. The fully developed lubricant film thicknesses (≥ 700 nm) are significantly higher than the surface roughness (≈ 25 nm) demonstrating a hydrodynamic lubrication. Hardly any scratches appeared on the post-experimental prosthesis with square-shaped dimple array and only a few scratches were found on the post-experimental prosthesis with triangular-shaped dimple arrays. Thus, prostheses with square-shaped dimple arrays could be a potential solution for durable artificial hip joints. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Innovative optical power detection array system for relative positioning of inner-formation flying system

    Science.gov (United States)

    Hou, Zhendong; Wang, Zhaokui; Zhang, Yulin

    2016-09-01

    The Inner-formation flying system (IFFS) is conceived to feature a spherical proof mass falling freely within a large cavity for space gravity detection, of which first application focuses on the Earth's gravity field recovery. For the IFFS, it is the relative position of the proof mass to its surrounding cavity that is feedback into thrusters for tracking control, even as part of data to detect gravity. Since the demonstration and verification of demanding technologies using small satellite platforms is a very sensible choice prior to detection mission, an optical power detection array system (OPDAS) is proposed to measure the relative position with advantages of low cost and high adaptability. Besides that, its large dynamic range can reduce the requirement for satellite platform and releasing mechanism, which is also an attracting trait for small satellite application. The concept of the OPDAS is firstly presented, followed by the algorithm to position the proof mass. Then the radiation pressure caused by the measuring beam is modeled, and its disturbance on the proof mass is simulated. The experimental system to test the performance of a prototype of the OPDAS is established, and the preliminary results show that a precision of less than 0.4 mm across a dynamic range of several centimeters can be reached by the prototype of the OPDAS.

  19. Monitoring the lesion formation during histotripsy treatment using shear wave imaging

    Science.gov (United States)

    Arnal, Bastien; Lee, Wei-Ning; Pernot, Mathieu; Fink, Mathias; Tanter, Mickael

    2012-11-01

    Monitoring the lesion formation induced by histotripsy has mainly relied on the quantitative change in backscatter intensity using ultrasound B-mode imaging. However, how the mechanical properties of the histotripsy-treated tissue region alter during the procedure is yet to be fully investigated. We thus proposed here to monitor such a therapeutic process based on shear modulus estimated by shear wave imaging (SWI). In the therapeutic procedure, a single-element piezo-composite focused transducer (Imasonic, Besançon, France) with a center frequency of 660 kHz, a focal length of 45 mm, and an fnumber of 1 was driven by a function generator (AFG 3101, Tektronix, Beaverton, OR) and a gated RF power amplifier (GA-2500A, RITEC Inc., USA) to generate ultrasound histotripsy pulses. Histotripsy pulses were delivered for 20 seconds and then followed by a 30-second pause and a rapid monitoring step. Such a treatment and monitoring scheme was repeated for 10 mins. Both the reference measurement and monitoring were realized by SWI, where plane shear waves were generated by an 8 MHz linear array probe connected to a prototype ultrasound scanner, and acquired at a frame rate of 10000 Hz. Shear modulus was estimated and mapped in 2D through a time-of-flight algorithm. Gelatin (8%)-agar (2%) phantoms and ex-vivo porcine liver samples were tested. Regions of interests (ROI's) of 2 mm-by-2 mm in both untreated and treated regions were selected to compute the contrast-to-noise ratio (CNR). In all three scenarios where different PD's and PRF's were implemented, during the first 100 seconds of the treatment, 50% decrease in the shear modulus within the histotripsy-targeted zone was already observed, and the CNR of the shear modulus increased by 18 dB. In contrast, the backscatter intensity began to reduce and the corresponding CNR was found to increase by 6 dB only after 120 seconds of treatment. The results demonstrated that SWI can map quantitatively the change of mechanical

  20. Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications

    Directory of Open Access Journals (Sweden)

    Raja Sufi

    2011-01-01

    Full Text Available Abstract A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N, N-dimethylformamide and hydrofluoric acid, which essentially leads to the formation of macroporous silicon templates. A reasonable control over the dimensions of the structures could be achieved by tailoring the formation parameters, primarily the wafer resistivity. For a micro test tube, the cross-section (i.e., the pore size as well as the distance of separation between two adjacent test tubes (i.e., inter-pore distance is typically approximately 1 μm, whereas, for a microbeaker the pore size exceeds 1.5 μm and the inter-pore distance could be less than 100 nm. We successfully synthesized superparamagnetic iron oxide nanoparticles (SPIONs, with average particle size approximately 20 nm and attached them on the porous silicon chip surface as well as on the pore walls. Such SPION-coated arrays of micro test tubes and microbeakers are potential candidates for biosensors because of the biocompatibility of both silicon and SPIONs. As acquisition of data via microarray is an essential attribute of high throughput bio-sensing, the proposed nanostructured array may be a promising step in this direction.

  1. Double-walled ZrO{sub 2} nanotube array. Preparation and enhanced photocatalytic activity

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Chaorui; Hu, Shengliang; Chang, Qing; Wang, Yanzhong [School of Materials Science and Engineering, North University of China, Taiyuan (China); Yang, Jinlong [School of Materials Science and Engineering, North University of China, Taiyuan (China); School of Materials Science and Engineering, Tsinghua University, Beijing (China)

    2017-11-15

    This work demonstrates the formation of self-ordered double-walled ZrO{sub 2} nanotube array via electrochemical anodization in glycerol-based electrolyte. Compared with its counterpart of single-walled ZrO{sub 2} nanotube array, the tube wall of double-walled ZrO{sub 2} nanotube split into outer and inner layers for the decomposition of glycerol during anodization process. Moreover, the double-walled structure showed its advantage of achieving improved utilization of light and higher specific surface area of nanotube array. Due to the unique double-walled structure, the double-walled ZrO{sub 2} nanotube array exhibited better photocatalytic activity than the single-walled ZrO{sub 2} nanotube array. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  2. Recepcion of Rousseau in formation initial of primary school teachers (Spain, 20th century

    Directory of Open Access Journals (Sweden)

    Antonio Viñao, España.

    2013-08-01

    Full Text Available Este artigo aborda a imagem e idéias de e sobre Rousseau transmitidas na Espanha ao magistério primário durante o século 20, através dos manuais de História da Educação e outras fontes similares. Após analisar as fontes utilizadas e seus destinatários, se expõe a imagem e a idéia de Rousseau como pai da pedagogia moderna, predominante nos escritos pedagógicos da época para, em seguida, e a modo de contraste, examinar o lugar e o tratamento dado à Rousseau nos mencionados manuais. Esse exame se divide em duas épocas: a anterior à guerra civil e a posterior, com o fim de mostrar o predomínio, sobre tudo durante o franquismo, de uma visão católica, conservadora, moralizante e crítica do genebriano. Palavras-chave: Rousseau, manuais escolares, educação primária, formação do magistério primário, Espanha (século 20.   Recepcion of Rousseau in formation initial of primary school teachers (Spain, 20th century Abstract This article deals with Rousseau’s images and ideas present in the school books of History of Education, and other similar sources, used in the training of primary school teachers in Spain during the 20th century. After analyzing the sources used and their addresses, the predominance of Rousseau’s ideas and image as the father of modern pedagogy in the pedagogical literature of this period is explained. Immediately after, by way of contrast, Rousseau’s place and the way of considering him in the above mentioned school books are examined. The above analysis is divided into two periods, before and after the civil war, in order to show the predominance of the catholic-conservative moralizing and critical approach, particularly during francoism. Key-words: Rousseau, school books, primary education, teacher’s training, Spain (20th century.   La recepción de Rousseau en la formación inicial del magisterio primario (España, siglo 20 Resumen Este artículo versa sobre la imagen e ideas de y sobre Rousseau

  3. Manipulation and Investigation of Uniformly-Spaced Nanowire Array on a Substrate via Dielectrophoresis and Electrostatic Interaction

    Directory of Open Access Journals (Sweden)

    U Hyeok Choi

    2018-06-01

    Full Text Available Directed-assembly of nanowires on the dielectrics-covered parallel electrode structure is capable of producing uniformly-spaced nanowire array at the electrode gap due to dielectrophoretic nanowire attraction and electrostatic nanowire repulsion. Beyond uniformly-spaced nanowire array formation, the control of spacing in the array is beneficial in that it should be the experimental basis of the precise positioning of functional nanowires on a circuit. Here, we investigate the material parameters and bias conditions to modulate the nanowire spacing in the ordered array, where the nanowire array formation is readily attained due to the electrostatic nanowire interaction. A theoretical model for the force calculation and the simulation of the induced charge in the assembled nanowire verifies that the longer nanowires on thicker dielectric layer tend to be assembled with a larger pitch due to the stronger nanowire-nanowire electrostatic repulsion, which is consistent with the experimental results. It was claimed that the stronger dielectrophoretic force is likely to attract more nanowires that are suspended in solution at the electrode gap, causing them to be less-spaced. Thus, we propose a generic mechanism, competition of dielectrophoretic and electrostatic force, to determine the nanowire pitch in an ordered array. Furthermore, this spacing-controlled nanowire array offers a way to fabricate the high-density nanodevice array without nanowire registration.

  4. Update-in-Place Analysis for True Multidimensional Arrays

    Directory of Open Access Journals (Sweden)

    Steven M. Fitzgerald

    1996-01-01

    Full Text Available Applicative languages have been proposed for defining algorithms for parallel architectures because they are implicitly parallel and lack side effects. However, straightforward implementations of applicative-language compilers may induce large amounts of copying to preserve program semantics. The unnecessary copying of data can increase both the execution time and the memory requirements of an application. To eliminate the unnecessary copying of data, the Sisal compiler uses both build-in-place and update-in-place analyses. These optimizations remove unnecessary array copy operations through compile-time analysis. Both build-in-place and update-in-place are based on hierarchical ragged arrays, i.e., the vector-of-vectors array model. Although this array model is convenient for certain applications, many optimizations are precluded, e.g., vectorization. To compensate for this deficiency, new languages, such as Sisal 2.0, have extended array models that allow for both high-level array operations to be performed and efficient implementations to be devised. In this article, we introduce a new method to perform update-in-place analysis that is applicable to arrays stored either in hierarchical or in contiguous storage. Consequently, the array model that is appropriate for an application can be selected without the loss of performance. Moreover, our analysis is more amenable for distributed memory and large software systems.

  5. Synergism of Dewetting and Self-Wrinkling To Create Two-Dimensional Ordered Arrays of Functional Microspheres.

    Science.gov (United States)

    Han, Xue; Hou, Jing; Xie, Jixun; Yin, Jian; Tong, Yi; Lu, Conghua; Möhwald, Helmuth

    2016-06-29

    Here we report a simple, novel, yet robust nonlithographic method for the controlled fabrication of two-dimensional (2-D) ordered arrays of polyethylene glycol (PEG) microspheres. It is based on the synergistic combination of two bottom-up processes enabling periodic structure formation for the first time: dewetting and the mechanical wrinkle formation. The deterministic dewetting results from the hydrophilic polymer PEG on an incompatible polystyrene (PS) film bound to a polydimethylsiloxane (PDMS) substrate, which is directed both by a wrinkled template and by the template-directed in-situ self-wrinkling PS/PDMS substrate. Two strategies have been introduced to achieve synergism to enhance the 2-D ordering, i.e., employing 2-D in-situ self-wrinkling substrates and boundary conditions. As a result, we achieve highly ordered 2-D arrays of PEG microspheres with desired self-organized microstructures, such as the array location (e.g., selectively on the crest/in the valley of the wrinkles), diameter, spacing of the microspheres, and array direction. Additionally, the coordination of PEG with HAuCl4 is utilized to fabricate 2-D ordered arrays of functional PEG-HAuCl4 composite microspheres, which are further converted into different Au nanoparticle arrays. This simple versatile combined strategy could be extended to fabricate highly ordered 2-D arrays of other functional materials and achieve desirable properties and functionalities.

  6. Critical ratios in harbor porpoises (Phocoena phocoena) for tonal signals between 0.315 and 150 kHz in random Gaussian white noise.

    Science.gov (United States)

    Kastelein, Ronald A; Wensveen, Paul J; Hoek, Lean; Au, Whitlow W L; Terhune, John M; de Jong, Christ A F

    2009-09-01

    A psychoacoustic behavioral technique was used to determine the critical ratios (CRs) of two harbor porpoises for tonal signals with frequencies between 0.315 and 150 kHz, in random Gaussian white noise. The masked 50% detection hearing thresholds were measured using a "go/no-go" response paradigm and an up-down staircase psychometric method. CRs were determined at one masking noise level for each test frequency and were similar in both animals. For signals between 0.315 and 4 kHz, the CRs were relatively constant at around 18 dB. Between 4 and 150 kHz the CR increased gradually from 18 to 39 dB ( approximately 3.3 dB/octave). Generally harbor porpoises can detect tonal signals in Gaussian white noise slightly better than most odontocetes tested so far. By combining the mean CRs found in the present study with the spectrum level of the background noise levels at sea, the basic audiogram, and the directivity index, the detection threshold levels of harbor porpoises for tonal signals in various sea states can be calculated.

  7. Infrared focal plane array producibility and related materials; Proceedings of the Meeting, Orlando, FL, Apr. 20, 21, 1992

    Science.gov (United States)

    Balcerak, Ray; Pellegrini, Paul W.; Scribner, Dean A.

    The present conference discusses the commercial diversification of the U.S. IR detector industry's commercial diversification, HgCdTe focal-plane array (FPAs) manufacture, LPE of (Hg,Cd)Te FPAs, uncooled IR FPA detector producibility, a high performance staring IR camera, and novel technologies for FPA dewars. Also discussed are hybridizing FPAs, cryoprober test development, HgCdTe on Si for monolithic focal plane arrays, popcorn noise in linear InGaAs detector arrays, and the use of narrowband laser speckle for MTF characterization of CCDs. (No individual items are abstracted in this volume)

  8. Radiation-hardened optically reconfigurable gate array exploiting holographic memory characteristics

    Science.gov (United States)

    Seto, Daisaku; Watanabe, Minoru

    2015-09-01

    In this paper, we present a proposal for a radiation-hardened optically reconfigurable gate array (ORGA). The ORGA is a type of field programmable gate array (FPGA). The ORGA configuration can be executed by the exploitation of holographic memory characteristics even if 20% of the configuration data are damaged. Moreover, the optoelectronic technology enables the high-speed reconfiguration of the programmable gate array. Such a high-speed reconfiguration can increase the radiation tolerance of its programmable gate array to 9.3 × 104 times higher than that of current FPGAs. Through experimentation, this study clarified the configuration dependability using the impulse-noise emulation and high-speed configuration capabilities of the ORGA with corrupt configuration contexts. Moreover, the radiation tolerance of the programmable gate array was confirmed theoretically through probabilistic calculation.

  9. Distributed Acoustic Sensing (DAS) Array near a Highway for Traffic Monitoring and Near-Surface Shear-Wave Velocity Profiles

    Science.gov (United States)

    Wang, H. F.; Fratta, D.; Lancelle, C.; Ak, E. Ms; Lord, N. E.

    2017-12-01

    Monitoring traffic is important for many technical reasons. It allows for better design of future roads and assessment of the state of current roads. The number, size, weight, and speed of vehicles control deterioration rate. Also, real-time information supplies data to intelligent information systems to help control traffic. Recently there have been studies looking at monitoring traffic seismically as vibrations from traffic are not sensitive to weather and poor visibility. Furthermore, traffic noise can be used to image S-wave velocity distribution in the near surface by capturing and interpreting Rayleigh and Love waves (Nakata, 2016; Zeng et al. 2016). The capability of DAS for high spatial sampling (1 m), temporal sampling (up to 10 kHz), and distributed nature (tens of kilometers) allows for a closer look at the traffic as it passes and how the speed of the vehicle may change over the length of the array. The potential and difficulties of using DAS for these objectives were studied using two DAS arrays. One at Garner Valley in Southern California (a 700-meter array adjacent to CA Highway 74) and another in Brady Hot Springs, Nevada (an 8700-meter array adjacent to Interstate 80). These studies experimentally evaluated the use of DAS data for monitoring traffic and assessing the use of traffic vibration as non-localized sources for seismic imaging. DAS arrays should also be resilient to issues with lighting conditions that are problematic for video monitoring and it may be sensitive to the weight of a vehicle. This study along a major interstate provides a basis for examining DAS' potential and limitations as a key component of intelligent highway systems.

  10. Brazilian Decimetric Array (BDA) project - Phase II

    Science.gov (United States)

    Faria, C.; Stephany, S.; Sawant, H. S.; Cecatto, J. R.; Fernandes, F. C. R.

    2010-02-01

    The configuration of the second phase of the Brazilian Decimetric Array (BDA), installed at Cachoeira Paulista, Brazil (Longitude 45° 0‧ 20″ W and Latitude 22° 41‧ 19″ S), is a T-shaped array where 21 antennas are being added to existing 5 antennas of the first phase. In the third phase, in each arm of the T array, four more antennas will be added and baselines will be increased to 2.5 × 1.25 km in east-west and south directions, respectively. The antennas will be equally spaced at the distances of 250 meters from the central antenna of the T-array. Also, the frequency range will be increased to 1.2-1.7, 2.8 and 5.6 GHz. The Second phase of the BDA should be operational by the middle of 2010 and will operate in the frequency range of (1.2-1.7) GHz for solar and non solar observations. Here, we present the characteristics of the second phase of the BDA project, details of the array configuration, the u-v coverage, the synthesized beam obtained for the proposed configuration.

  11. One-step synthesis of CdTe branched nanowires and nanorod arrays

    International Nuclear Information System (INIS)

    Hou Junwei; Yang Xiuchun; Lv Xiaoyi; Peng Dengfeng; Huang Min; Wang Qingyao

    2011-01-01

    Single crystalline CdTe branched nanowires and well-aligned nanorod arrays were simultaneously synthesized by a simple chemical vapor deposition (CVD) technique. X-ray diffraction (XRD), scanning electronic microscopy (SEM), transmission electronic microscopy (TEM) and selected area electronic diffraction (SAED) were used to study the crystalline structure, composition and morphology of different samples. Vapor-liquid-solid (VLS) and vapor-solid (VS) processes were proposed for the formation of the CdTe branched nanowires and nanorod arrays, respectively. As-grown CdTe nanorod arrays show a strong red emission band centered at about 620 nm, which can be well fitted by two Gaussian curves centered at 610 nm and 635 nm, respectively.

  12. Topic 2.0: Tropical cyclone formation and extratropical transition

    OpenAIRE

    Harr, Patrick A.

    2010-01-01

    Approved for public release; distribution is unlimited In this section, progress since ITWC-VI on research, observations and forecasting of tropical cyclone formation and extratropical transition is summarized. While tropical cyclone formation and extratropical transition are stages at opposite ends of the tropical cyclone lifecycle, significant lack of understanding remains in relation to processes associated with each stage. Formation and extratropical transition involve interactions a...

  13. Profiles of zonal flows and turbulence mode numbers and probe system in the HL-2A tokamak

    International Nuclear Information System (INIS)

    Hong Wenyu; Zhao Kaijun; Yan Longwen; Dong Jiaqi; Cheng Jun; Qian Jun

    2009-01-01

    The toroidal and poloidal symmetries (m-0, n-0) of the measured low frequency zonal flows (f=0-5 kHz) and geodesic acoustic mode zonal flow (f=16 kHz) electric potential and radial promulgate features were unambiguously identified with displaced Langmuir probe arrays in the edge plasma of the HL-2A tokamak for the first time. The finite radial wave vector (K r-LF =0.6 cm -1 , K r-GAM =2 cm -1 ) of the flows was simultaneously estimated. The formation mechanism of the flows is identified to be nonlinear three wave coupling between high frequency turbulent fluctuations and the flows. Changes of zonal flow amplitude bring by ECRH power and the boundary safety factors were simply studied. Moreover, change of zonal flow amplitude in radial direction was too observed. (authors)

  14. Geometrical optics, electrostatics, and nanophotonic resonances in absorbing nanowire arrays.

    Science.gov (United States)

    Anttu, Nicklas

    2013-03-01

    Semiconductor nanowire arrays have shown promise for next-generation photovoltaics and photodetection, but enhanced understanding of the light-nanowire interaction is still needed. Here, we study theoretically the absorption of light in an array of vertical InP nanowires by moving continuously, first from the electrostatic limit to the nanophotonic regime and then to the geometrical optics limit. We show how the absorption per volume of semiconductor material in the array can be varied by a factor of 200, ranging from 10 times weaker to 20 times stronger than in a bulk semiconductor sample.

  15. Wafer-scale fabrication of uniform Si nanowire arrays using the Si wafer with UV/Ozone pretreatment

    International Nuclear Information System (INIS)

    Bai, Fan; Li, Meicheng; Huang, Rui; Yu, Yue; Gu, Tiansheng; Chen, Zhao; Fan, Huiyang; Jiang, Bing

    2013-01-01

    The electroless etching technique combined with the process of UV/Ozone pretreatment is presented for wafer-scale fabrication of the silicon nanowire (SiNW) arrays. The high-level uniformity of the SiNW arrays is estimated by the value below 0.2 of the relative standard deviation of the reflection spectra on the 4-in. wafer. Influence of the UV/Ozone pretreatment on the formation of SiNW arrays is investigated. It is seen that a very thin SiO 2 produced by the UV/Ozone pretreatment improves the uniform nucleation of Ag nanoparticles (NPs) on the Si surface because of the effective surface passivation. Meanwhile, the SiO 2 located among the adjacent Ag NPs can obstruct the assimilation growth of Ag NPs, facilitating the deposition of the uniform and dense Ag NPs catalysts, which induces the formation of the SiNW arrays with good uniformity and high filling ratio. Furthermore, the remarkable antireflective and hydrophobic properties are observed for the SiNW arrays which display great potential in self-cleaning antireflection applications

  16. Visualization and characterization of interfacial polymerization layer formation

    NARCIS (Netherlands)

    Zhang, Yali; Benes, Nieck Edwin; Lammertink, Rob G.H.

    2015-01-01

    We present a microfluidic platform to visualize the formation of free-standing films by interfacial polymerization. A microfluidic device is fabricated, with an array of micropillars to stabilize an aqueous–organic interface that allows a direct observation of the films formation process via optical

  17. Apertif: A new phased-array feed for WSRT

    Science.gov (United States)

    Adams, Elizabeth; Adebahr, Björn; de Blok, Willem J. G.; Hess, Kelley M.; Lucero, Danielle M.; Maccagni, Filippo; Morganti, Raffaella; Oosterloo, Tom A.; Ponomareva, Anastasia; Staveley-Smith, Lister; van der Hulst, J. M.; Verheijen, Marc A. W.; Verstappen, Joris

    2018-01-01

    Apertif is a phased-array feed for the Westerbork Synthesis Radio Telescope (WSRT), increasing the field of view of the telescope by a factor of twenty-five to 6.8 square degrees. In 2018, three legacy surveys will commence: a shallow imaging survey, a medium-deep imaging survey, and a pulsars and fast transients survey. The imaging surveys will be done in full polarization over the frequency range 1130-1430 MHz, which corresponds to redshifts of z=0-0.256 for neutral hydrogen (HI). The spectral resolution is 12.2 kHz, or an HI velocity resolution of 2.6 km/s at z=0 and 3.2 km/s at z=0.256. The full resolution images will have a beam size of 15"x15"/sin(declination), and tapered data products (i.e., 30" resolution images) will also be available. The footprints of the imaging surveys are chosen to maximize coverage of multi-wavelength datasets, including the Herschel Atlas North Galactic Pole field, HetDex region, plus coordination with MaNGA and planned WEAVE follow-up. The survey footprints were also chosen to probe different regions of interest, including the CVn region, Coma cluster, and Perseus-Pisces supercluster. The key science cases for the imaging surveys include understanding how galaxy properties depend on environment, the role of interactions and gas accretion and removal, understanding the smallest gas-rich galaxies, connecting cold gas to AGN, understanding the history of star formation and AGN activity in the faint radio continuum population, and studying magnetic fields in galaxies and large-scale structure. After a proprietary period, the survey data products will be publicly available through the Apertif Long Term Archive (ALTA). Up-to-date information on Apertif and the planned surveys can be found at www.apertif.nl.Commissioning of the Apertif instrument is underway. Here we will present results from the imaging commissioning, highlighting the capabilities of the instrument as related to the key science cases of the imaging surveys.

  18. Design and operational experience and testing of 50 kW/120 kHz oscillator for 3 MeV, 30 kW DC accelerator

    International Nuclear Information System (INIS)

    Srivastava, S.K.; Bakhtsingh, R.I.; Saroj, P.C.

    2011-01-01

    A 3 MeV, 30 kW dc industrial electron beam Accelerator is being developed at EBC, Kharghar, Navi Mumbai. The 3 MV dc is generated by parallel coupled voltage multiplier operating at 120 kHz. This requires an input voltage of 150 kV-0-150 kV at 120 kHz. This is achieved by 50 kW/120 kHz power oscillator in conjunction with a tuned air-core step-up transformer. Input primary voltage of 6 kV-0-6 kV at 120 kHz is generated by an oscillator using BW1121J2 water cooled triodes in push-pull Colpitts configuration. The tank circuit for the oscillator is formed by the secondary winding inductance of the step-up transformer and capacitance formed by RF feeder electrodes of the voltage multiplier column. Grid feedback for the oscillator is derived by arranging a set of electrodes in the feeder assembly in a capacitive divider configuration. The oscillator is operated in class-C mode with grid leak bias for better efficiency which also has the advantages of self-adjustment with varying load conditions. High power test has been conducted in a simulated test set-up on dummy load up to 30kW. Subsequently, the power oscillator has been tested with HV multiplier at 1MeV level satisfactorily. This paper describes the design, test results and operational experiences of the oscillator. (author)

  19. Micromachined capacitive ultrasonic immersion transducer array

    Science.gov (United States)

    Jin, Xuecheng

    Capacitive micromachined ultrasonic transducers (cMUTs) have emerged as an attractive alternative to conventional piezoelectric ultrasonic transducers. They offer performance advantages of wide bandwidth and sensitivity that have heretofore been attainable. In addition, micromachining technology, which has benefited from the fast-growing microelectronics industry, enables cMUT array fabrication and electronics integration. This thesis describes the design and fabrication of micromachined capacitive ultrasonic immersion transducer arrays. The basic transducer electrical equivalent circuit is derived from Mason's theory. The effects of Lamb waves and Stoneley waves on cross coupling and acoustic losses are discussed. Electrical parasitics such as series resistance and shunt capacitance are also included in the model of the transducer. Transducer fabrication technology is systematically studied. Device dimension control in both vertical and horizontal directions, process alternatives and variations in membrane formation, via etch and cavity sealing, and metalization as well as their impact on transducer performance are summarized. Both 64 and 128 element 1-D array transducers are fabricated. Transducers are characterized in terms of electrical input impedance, bandwidth, sensitivity, dynamic range, impulse response and angular response, and their performance is compared with theoretical simulation. Various schemes for cross coupling reduction is analyzed, implemented, and verified with both experiments and theory. Preliminary results of immersion imaging are presented using 64 elements 1-D array transducers for active source imaging.

  20. GaN Nanowire Arrays for High-Output Nanogenerators

    KAUST Repository

    Huang, Chi-Te

    2010-04-07

    Three-fold symmetrically distributed GaN nanowire (NW) arrays have been epitaxially grown on GaN/sapphire substrates. The GaN NW possesses a triangular cross section enclosed by (0001), (2112), and (2112) planes, and the angle between the GaN NW and the substrate surface is ∼62°. The GaN NW arrays produce negative output voltage pulses when scanned by a conductive atomic force microscope in contact mode. The average of piezoelectric output voltage was about -20 mV, while 5-10% of the NWs had piezoelectric output voltages exceeding -(0.15-0.35) V. The GaN NW arrays are highly stable and highly tolerate to moisture in the atmosphere. The GaN NW arrays demonstrate an outstanding potential to be utilized for piezoelectric energy generation with a performance probably better than that of ZnO NWs. © 2010 American Chemical Society.

  1. The Argonne silicon strip-detector array

    Energy Technology Data Exchange (ETDEWEB)

    Wuosmaa, A H; Back, B B; Betts, R R; Freer, M; Gehring, J; Glagola, B G; Happ, Th; Henderson, D J; Wilt, P [Argonne National Lab., IL (United States); Bearden, I G [Purdue Univ., Lafayette, IN (United States). Dept. of Physics

    1992-08-01

    Many nuclear physics experiments require the ability to analyze events in which large numbers of charged particles are detected and identified simultaneously, with good resolution and high efficiency, either alone, or in coincidence with gamma rays. The authors have constructed a compact large-area detector array to measure these processes efficiently and with excellent energy resolution. The array consists of four double-sided silicon strip detectors, each 5x5 cm{sup 2} in area, with front and back sides divided into 16 strips. To exploit the capability of the device fully, a system to read each strip-detector segment has been designed and constructed, based around a custom-built multi-channel preamplifier. The remainder of the system consists of high-density CAMAC modules, including multi-channel discriminators, charge-sensing analog-to-digital converters, and time-to-digital converters. The array`s performance has been evaluated using alpha-particle sources, and in a number of experiments conducted at Argonne and elsewhere. Energy resolutions of {Delta}E {approx} 20-30 keV have been observed for 5 to 8 MeV alpha particles, as well as time resolutions {Delta}T {<=} 500 ps. 4 figs.

  2. Tipe Dry Cell dan Wet Cell berdimensi 80 x 80 mm dengan Penambahan PWM E-3 FF (1 kHz

    Directory of Open Access Journals (Sweden)

    Yanur Arzaqa Ghiffari

    2013-09-01

    Full Text Available Ketersediaan bahan bakar minyak semakin terbatas dan hasil pembakarannya berdampak pada pencemaran lingkungan, salah satu solusinya dengan memanfaatkan gas HHO pada kendaraan bermotor. Penelitian dengan sistem direct connection, temperatur mencapai lebih dari 90oC menyebabkan  generator HHO menjadi rusak dan meleleh, maka penelitian ini menambahan alat untuk mengkontrol besarnya arus, frekuensi, dan duty cycle. Pengembangan generator HHO menggunakan tipe kering (dry cell dan tipe basah (wet cell dengan penambahan PWM (Pulse Width Modulation E-3 Fixed Frequency 1 kHz divariasikan berupa duty cycle: 20%, 40%, 60%, 80%  dan direct connection. Pengujian dilakukan di Laboratorium Teknik Pembakaran dan Bahan Bakar - Teknik Mesin ITS.  Dari hasil penelitian didapatkan karakteristik unjuk kerja terbaik pada kedua tipe generator HHO dengan penambahan PWM. Nilai arus dan tegangan lebih stabil dibandingkan dengan tanpa penambahan PWM (direct connection, namun arus cenderung meningkat seiring dengan kenaikan temperatur mencapai 70oC. Efisiensi terbaik pada generator tipe wet dengan duty cycle 80%,  yaitu 27,7 %.

  3. Design of DSP-based high-power digital solar array simulator

    Science.gov (United States)

    Zhang, Yang; Liu, Zhilong; Tong, Weichao; Feng, Jian; Ji, Yibo

    2013-12-01

    To satisfy rigid performance specifications, a feedback control was presented for zoom optical lens plants. With the increasing of global energy consumption, research of the photovoltaic(PV) systems get more and more attention. Research of the digital high-power solar array simulator provides technical support for high-power grid-connected PV systems research.This paper introduces a design scheme of the high-power digital solar array simulator based on TMS320F28335. A DC-DC full-bridge topology was used in the system's main circuit. The switching frequency of IGBT is 25kHz.Maximum output voltage is 900V. Maximum output current is 20A. Simulator can be pre-stored solar panel IV curves.The curve is composed of 128 discrete points .When the system was running, the main circuit voltage and current values was feedback to the DSP by the voltage and current sensors in real-time. Through incremental PI,DSP control the simulator in the closed-loop control system. Experimental data show that Simulator output voltage and current follow a preset solar panels IV curve. In connection with the formation of high-power inverter, the system becomes gridconnected PV system. The inverter can find the simulator's maximum power point and the output power can be stabilized at the maximum power point (MPP).

  4. Performance analysis of solar cell arrays in concentrating light intensity

    International Nuclear Information System (INIS)

    Xu Yongfeng; Li Ming; Lin Wenxian; Wang Liuling; Xiang Ming; Zhang Xinghua; Wang Yunfeng; Wei Shengxian

    2009-01-01

    Performance of concentrating photovoltaic/thermal system is researched by experiment and simulation calculation. The results show that the I-V curve of the GaAs cell array is better than that of crystal silicon solar cell arrays and the exergy produced by 9.51% electrical efficiency of the GaAs solar cell array can reach 68.93% of the photovoltaic/thermal system. So improving the efficiency of solar cell arrays can introduce more exergy and the system value can be upgraded. At the same time, affecting factors of solar cell arrays such as series resistance, temperature and solar irradiance also have been analyzed. The output performance of a solar cell array with lower series resistance is better and the working temperature has a negative impact on the voltage in concentrating light intensity. The output power has a -20 W/V coefficient and so cooling fluid must be used. Both heat energy and electrical power are then obtained with a solar trough concentrating photovoltaic/thermal system. (semiconductor devices)

  5. Chemistry and Star Formation: A Love-Hate Relationship

    Science.gov (United States)

    Jiménez-Serra, Izaskun; Zhang, Qizhou; Patel, Nimesh; Lu, Xing; Wang, Ke; Testi, Leonardo; Caselli, Paola; Martin-Pintado, Jesus

    2014-06-01

    The development of the broad bandwidth receivers at the Submillimeter Array (SMA) a decade ago opened up the possibility to observe tens of molecular lines at high angular resolution simultaneously. The unprecedented wealth of molecular line data provided by the SMA allowed for the first time detailed studies of the chemistry in star-forming regions. These studies have revealed that chemistry is a useful tool to pin down the internal physical structure and the physical processes involved in the process of low-mass and high-mass star formation. In this talk, I will review the most important advances in our understanding of the star-formation process through chemistry thanks to the SMA, and I will present the challenges that will be faced in the next decade in this field of research thanks to the advent of new instrumentation such as the Atacama Large Millimeter/Submillimeter Array and the Square Kilometer Array.

  6. Ku-Band Traveling Wave Slot Array Using Simple Scanning Control

    Science.gov (United States)

    Host, Nicholas K.; Chen, Chi-Chih; Volakis, John L.; Miranda, Felix A.

    2015-01-01

    This paper introduces a feeding concept aimed at simplifying the backend (phase shifters) of traditional phased arrays. As an alternative to traditional phased arrays, we employ a traveling wave array (TWA) using a single feedline whose propagation constant is controlled via a single, small mechanical movement without a need for phase shifters to enable scanning. Specifically, a dielectric plunger is positioned within a parallel plate waveguide (PPW) transmission line (TL) that feeds the TWA. By adjusting the position of the dielectric plunger within the PPW feeding the TWA, beam steering is achieved. A 20 element array is designed at 13GHz shown to give stable realized gain across the angular range of -25 deg. less than or equal to theta less than or equal to 25 deg. A proof of concept array is fabricated and measured to demonstrate and validate the concept's operation.

  7. Focal plane array with modular pixel array components for scalability

    Science.gov (United States)

    Kay, Randolph R; Campbell, David V; Shinde, Subhash L; Rienstra, Jeffrey L; Serkland, Darwin K; Holmes, Michael L

    2014-12-09

    A modular, scalable focal plane array is provided as an array of integrated circuit dice, wherein each die includes a given amount of modular pixel array circuitry. The array of dice effectively multiplies the amount of modular pixel array circuitry to produce a larger pixel array without increasing die size. Desired pixel pitch across the enlarged pixel array is preserved by forming die stacks with each pixel array circuitry die stacked on a separate die that contains the corresponding signal processing circuitry. Techniques for die stack interconnections and die stack placement are implemented to ensure that the desired pixel pitch is preserved across the enlarged pixel array.

  8. Vibrational sum-frequency generation spectroscopy of lipid bilayers at repetition rates up to 100 kHz

    Science.gov (United States)

    Yesudas, Freeda; Mero, Mark; Kneipp, Janina; Heiner, Zsuzsanna

    2018-03-01

    Broadband vibrational sum-frequency generation (BB-VSFG) spectroscopy has become a well-established surface analytical tool capable of identifying the orientation and structure of molecular layers. A straightforward way to boost the sensitivity of the technique could be to increase the laser repetition rate beyond that of standard BB-VSFG spectrometers, which rely on Ti:sapphire lasers operating at repetition rates of 1-5 kHz. Nevertheless, possible thermally induced artifacts in the vibrational spectra due to higher laser average powers are unexplored. Here, we discuss laser power induced temperature accumulation effects that distort the BB-VSFG spectra of 1,2-diacyl-sn-glycero-3-phosphocholine at an interface between two transparent phases at repetition rates of 5, 10, 50, and 100 kHz at constant pulse energy. No heat-induced distortions were found in the spectra, suggesting that the increase in the laser repetition rate provides a feasible route to an improved signal-to-noise ratio or shorter data acquisition times in BB-VSFG spectroscopy for thin films on transparent substrates. The results have implications for future BB-VSFG spectrometers pushing the detection limit for molecular layers with low surface coverage.

  9. Modification of the ultrasound induced activity by the presence of an electrode in a sono-reactor working at two low frequencies (20 and 40 kHz). Part II: Mapping flow velocities by particle image velocimetry (PIV).

    Science.gov (United States)

    Mandroyan, A; Doche, M L; Hihn, J Y; Viennet, R; Bailly, Y; Simonin, L

    2009-01-01

    Sonoelectrochemical experiments differ from sonochemical ones by the introduction of electrodes in the sonicated reaction vessel. The aim of the study is to characterize the changes in the ultrasonic activity induced by the presence of an electrode located in front of the transducer. The scope of our investigations concerns two low frequency vibration modes: 20 and 40 kHz. For this purpose, two laser visualization techniques have been used. The first part of the study, described in a previous paper (Part I), deals with the laser tomography technique which provides an accurate picture of the reactor active zones, related to numerous cavitation events. The second part of the paper (Part II) will describe the particle image velocimetry (PIV) technique used to measure the velocity vector field in the fluid portion between the horn and the electrode. As for the previous study, two parameters were studied: the electrical power supplied to the transducer and the electrode/transducer distance. The velocity vector fields show a main flow in the reactor axis. This flow seems to correspond to the conical cavitation bubbles structure which is observed on the laser tomography pictures. When an electrode is introduced into the reactor, two additional symmetric transversal flows can be quantified on both sides of the electrode.

  10. Timed arrays wideband and time varying antenna arrays

    CERN Document Server

    Haupt, Randy L

    2015-01-01

    Introduces timed arrays and design approaches to meet the new high performance standards The author concentrates on any aspect of an antenna array that must be viewed from a time perspective. The first chapters briefly introduce antenna arrays and explain the difference between phased and timed arrays. Since timed arrays are designed for realistic time-varying signals and scenarios, the book also reviews wideband signals, baseband and passband RF signals, polarization and signal bandwidth. Other topics covered include time domain, mutual coupling, wideband elements, and dispersion. The auth

  11. Cavitation thresholds of contrast agents in an in vitro human clot model exposed to 120-kHz ultrasound.

    Science.gov (United States)

    Gruber, Matthew J; Bader, Kenneth B; Holland, Christy K

    2014-02-01

    Ultrasound contrast agents (UCAs) can be employed to nucleate cavitation to achieve desired bioeffects, such as thrombolysis, in therapeutic ultrasound applications. Effective methods of enhancing thrombolysis with ultrasound have been examined at low frequencies (cavitation thresholds for two UCAs exposed to 120-kHz ultrasound. A commercial ultrasound contrast agent (Definity(®)) and echogenic liposomes were investigated to determine the acoustic pressure threshold for ultraharmonic (UH) and broadband (BB) generation using an in vitro flow model perfused with human plasma. Cavitation emissions were detected using two passive receivers over a narrow frequency bandwidth (540-900 kHz) and a broad frequency bandwidth (0.54-1.74 MHz). UH and BB cavitation thresholds occurred at the same acoustic pressure (0.3 ± 0.1 MPa, peak to peak) and were found to depend on the sensitivity of the cavitation detector but not on the nucleating contrast agent or ultrasound duty cycle.

  12. Endogenous vasopressin, innate anxiety, and the emission of pro-social 50-kHz ultrasonic vocalizations during social play behavior in juvenile rats.

    Science.gov (United States)

    Lukas, Michael; Wöhr, Markus

    2015-06-01

    Although the involvement of the neuropeptide arginine vasopressin (AVP) in rodent social interaction is already extensively characterized, little is known about its role in social communication. Rats communicate in the ultrasonic range by means of ultrasonic vocalizations (USV). Depending on developmental stage and affective state, rats emit various distinct types of USV, with appetitive 50-kHz USV being induced by positive social interactions, like juvenile social play, probably serving an affiliative communicative function, namely to (re)establish or induce social proximity. In rats and mice selectively bred for low (LAB) and high (HAB) anxiety-related behavior, the emission of isolation-induced distress USV during maternal deprivation as pups correlates with innate high levels of hypothalamic AVP availability. Moreover, male LAB and HAB rats express deficits in social approach towards conspecifics, together with high and/or abnormal forms of aggression when confronted with harmless opponents, possibly due to a lack of social communication skills. The aim of this study was therefore (1) to investigate and characterize social play behavior and concomitant pro-social 50-kHz USV emission in male and female, juvenile LAB and HAB rats and to compare them to non-selected Wistar (NAB) rats; and (2) to link these findings pharmacologically to the central AVP system via applying an AVP 1a receptor (V1aR) antagonist (0.75 μg; Manning compound) or synthetic AVP (1 ng) into the lateral ventricle of male juvenile NAB rats. Our results show that reduced social play behavior in highly anxious male and female, juvenile HAB rats is accompanied by low amounts of pro-social 50-kHz USV, as compared to respective LAB and NAB rats, possibly reflecting a lack of positive affective states in expectation of or following social interactions in these individuals. Secondly, although synthetic AVP did not alter social play behavior and pro-social 50-kHz USV, we demonstrated for the first

  13. Signal Processing for a Lunar Array: Minimizing Power Consumption

    Science.gov (United States)

    D'Addario, Larry; Simmons, Samuel

    2011-01-01

    Motivation for the study is: (1) Lunar Radio Array for low frequency, high redshift Dark Ages/Epoch of Reionization observations (z =6-50, f=30-200 MHz) (2) High precision cosmological measurements of 21 cm H I line fluctuations (3) Probe universe before first star formation and provide information about the Intergalactic Medium and evolution of large scale structures (5) Does the current cosmological model accurately describe the Universe before reionization? Lunar Radio Array is for (1) Radio interferometer based on the far side of the moon (1a) Necessary for precision measurements, (1b) Shielding from earth-based and solar RFI (12) No permanent ionosphere, (2) Minimum collecting area of approximately 1 square km and brightness sensitivity 10 mK (3)Several technologies must be developed before deployment The power needed to process signals from a large array of nonsteerable elements is not prohibitive, even for the Moon, and even in current technology. Two different concepts have been proposed: (1) Dark Ages Radio Interferometer (DALI) (2)( Lunar Array for Radio Cosmology (LARC)

  14. Carbon Nanofiber Electrode Array for Neurochemical Monitoring

    Science.gov (United States)

    Koehne, Jessica E.

    2017-01-01

    A sensor platform based on vertically aligned carbon nanofibers (CNFs) has been developed. Their inherent nanometer scale, high conductivity, wide potential window, good biocompatibility and well-defined surface chemistry make them ideal candidates as biosensor electrodes. Here, we report using vertically aligned CNF as neurotransmitter recording electrodes for application in a smart deep brain stimulation (DBS) device. Our approach combines a multiplexed CNF electrode chip, developed at NASA Ames Research Center, with the Wireless Instantaneous Neurotransmitter Concentration Sensor (WINCS) system, developed at the Mayo Clinic. Preliminary results indicate that the CNF nanoelectrode arrays are easily integrated with WINCS for neurotransmitter detection in a multiplexed array format. In the future, combining CNF based stimulating and recording electrodes with WINCS may lay the foundation for an implantable smart therapeutic system that utilizes neurochemical feedback control while likely resulting in increased DBS application in various neuropsychiatric disorders. In total, our goal is to take advantage of the nanostructure of CNF arrays for biosensing studies requiring ultrahigh sensitivity, high-degree of miniaturization, and selective biofunctionalization.

  15. Preparation and characterization of CuO nanowire arrays

    International Nuclear Information System (INIS)

    Yu Dongliang; Ge Chuannan; Du Youwei

    2009-01-01

    CuO nanowire arrays were prepared by oxidation of copper nanowires embedded in anodic aluminum oxide (AAO) membranes. The AAO was fabricated in an oxalic acid at a constant voltage. Copper nanowires were formed in the nanopores of the AAO membranes in an electrochemical deposition process. The oxidized copper nanowires at different temperatures were studied. X-ray diffraction patterns confirmed the formation of a CuO phase after calcining at 500 0 C in air for 30 h. A transmission electron microscopy was used to characterize the nanowire morphologies. Raman spectra were performed to study the CuO nanowire arrays. After measuring, we found that the current-voltage curve of the CuO nanowires is nonlinear.

  16. Formation of array microstructures on silicon by multibeam interfered femtosecond laser pulses

    International Nuclear Information System (INIS)

    Zhao Quanzhong; Qiu Jianrong; Zhao Chongjun; Jiang Xiongwei; Zhu Congshan

    2005-01-01

    We report on an optical interference method to fabricate array microstructures on the surface of silicon wafers by means of five-beam interference of femtosecond laser pulses. Optical microscope and scanning electron microscope observations revealed microstructures with micrometer-order were fabricated. The diffraction characteristics of the fabricated structures were evaluated. The present technique allows one-step realization of functional optoelectronic devices on silicon surface

  17. DUAL POLARIZATION ANTENNA ARRAY WITH VERY LOW CROSS POLARIZATION AND LOW SIDE LOBES

    DEFF Research Database (Denmark)

    1997-01-01

    The present invention relates to an antenna array adapted to radiate or receive electromagnetic waves of one or two polarizations with very low cross polarization and low side lobes. An antenna array comprising many antenna elements, e.g. more than ten antenna elements, is provided in which...... formation of grating lobes are inhibited in selected directions of the radiation and cross polarization within the main lobe is suppressed at least 30 dB below the main lobe peak value. According to a preferred embodiment of the invention, the antenna elements of the antenna array comprise probe-fed patches...

  18. Opal-like Multicolor Appearance of Self-Assembled Photonic Array.

    Science.gov (United States)

    Arnon, Zohar A; Pinotsi, Dorothea; Schmidt, Matthias; Gilead, Sharon; Guterman, Tom; Sadhanala, Aditya; Ahmad, Shahab; Levin, Aviad; Walther, Paul; Kaminski, Clemens F; Fändrich, Marcus; Kaminski Schierle, Gabriele S; Adler-Abramovich, Lihi; Shimon, Linda J W; Gazit, Ehud

    2018-06-20

    Molecular self-assembly of short peptide building blocks leads to the formation of various material architectures that may possess unique physical properties. Recent studies had confirmed the key role of biaromaticity in peptide self-assembly, with the diphenylalanine (FF) structural family as an archetypal model. Another significant direction in the molecular engineering of peptide building blocks is the use of fluorenylmethoxycarbonyl (Fmoc) modification, which promotes the assembly process and may result in nanostructures with distinctive features and macroscopic hydrogel with supramolecular features and nanoscale order. Here, we explored the self-assembly of the protected, noncoded fluorenylmethoxycarbonyl-β,β-diphenyl-Ala-OH (Fmoc-Dip) amino acid. This process results in the formation of elongated needle-like crystals with notable aromatic continuity. By altering the assembly conditions, arrays of spherical particles were formed that exhibit strong light scattering. These arrays display vivid coloration, strongly resembling the appearance of opal gemstones. However, unlike the Rayleigh scattering effect produced by the arrangement of opal, the described optical phenomenon is attributed to Mie scattering. Moreover, by controlling the solution evaporation rate, i.e., the assembly kinetics, we were able to manipulate the resulting coloration. This work demonstrates a bottom-up approach, utilizing self-assembly of a protected amino acid minimal building block, to create arrays of organic, light-scattering colorful surfaces.

  19. Grammar-Based Specification and Parsing of Binary File Formats

    Directory of Open Access Journals (Sweden)

    William Underwood

    2012-03-01

    Full Text Available The capability to validate and view or play binary file formats, as well as to convert binary file formats to standard or current file formats, is critically important to the preservation of digital data and records. This paper describes the extension of context-free grammars from strings to binary files. Binary files are arrays of data types, such as long and short integers, floating-point numbers and pointers, as well as characters. The concept of an attribute grammar is extended to these context-free array grammars. This attribute grammar has been used to define a number of chunk-based and directory-based binary file formats. A parser generator has been used with some of these grammars to generate syntax checkers (recognizers for validating binary file formats. Among the potential benefits of an attribute grammar-based approach to specification and parsing of binary file formats is that attribute grammars not only support format validation, but support generation of error messages during validation of format, validation of semantic constraints, attribute value extraction (characterization, generation of viewers or players for file formats, and conversion to current or standard file formats. The significance of these results is that with these extensions to core computer science concepts, traditional parser/compiler technologies can potentially be used as a part of a general, cost effective curation strategy for binary file formats.

  20. Oligonucleotide arrays vs. metaphase-comparative genomic hybridisation and BAC arrays for single-cell analysis: first applications to preimplantation genetic diagnosis for Robertsonian translocation carriers.

    Science.gov (United States)

    Ramos, Laia; del Rey, Javier; Daina, Gemma; García-Aragonés, Manel; Armengol, Lluís; Fernandez-Encinas, Alba; Parriego, Mònica; Boada, Montserrat; Martinez-Passarell, Olga; Martorell, Maria Rosa; Casagran, Oriol; Benet, Jordi; Navarro, Joaquima

    2014-01-01

    Comprehensive chromosome analysis techniques such as metaphase-Comparative Genomic Hybridisation (CGH) and array-CGH are available for single-cell analysis. However, while metaphase-CGH and BAC array-CGH have been widely used for Preimplantation Genetic Diagnosis, oligonucleotide array-CGH has not been used in an extensive way. A comparison between oligonucleotide array-CGH and metaphase-CGH has been performed analysing 15 single fibroblasts from aneuploid cell-lines and 18 single blastomeres from human cleavage-stage embryos. Afterwards, oligonucleotide array-CGH and BAC array-CGH were also compared analysing 16 single blastomeres from human cleavage-stage embryos. All three comprehensive analysis techniques provided broadly similar cytogenetic profiles; however, non-identical profiles appeared when extensive aneuploidies were present in a cell. Both array techniques provided an optimised analysis procedure and a higher resolution than metaphase-CGH. Moreover, oligonucleotide array-CGH was able to define extra segmental imbalances in 14.7% of the blastomeres and it better determined the specific unbalanced chromosome regions due to a higher resolution of the technique (≈ 20 kb). Applicability of oligonucleotide array-CGH for Preimplantation Genetic Diagnosis has been demonstrated in two cases of Robertsonian translocation carriers 45,XY,der(13;14)(q10;q10). Transfer of euploid embryos was performed in both cases and pregnancy was achieved by one of the couples. This is the first time that an oligonucleotide array-CGH approach has been successfully applied to Preimplantation Genetic Diagnosis for balanced chromosome rearrangement carriers.

  1. Oligonucleotide arrays vs. metaphase-comparative genomic hybridisation and BAC arrays for single-cell analysis: first applications to preimplantation genetic diagnosis for Robertsonian translocation carriers.

    Directory of Open Access Journals (Sweden)

    Laia Ramos

    Full Text Available Comprehensive chromosome analysis techniques such as metaphase-Comparative Genomic Hybridisation (CGH and array-CGH are available for single-cell analysis. However, while metaphase-CGH and BAC array-CGH have been widely used for Preimplantation Genetic Diagnosis, oligonucleotide array-CGH has not been used in an extensive way. A comparison between oligonucleotide array-CGH and metaphase-CGH has been performed analysing 15 single fibroblasts from aneuploid cell-lines and 18 single blastomeres from human cleavage-stage embryos. Afterwards, oligonucleotide array-CGH and BAC array-CGH were also compared analysing 16 single blastomeres from human cleavage-stage embryos. All three comprehensive analysis techniques provided broadly similar cytogenetic profiles; however, non-identical profiles appeared when extensive aneuploidies were present in a cell. Both array techniques provided an optimised analysis procedure and a higher resolution than metaphase-CGH. Moreover, oligonucleotide array-CGH was able to define extra segmental imbalances in 14.7% of the blastomeres and it better determined the specific unbalanced chromosome regions due to a higher resolution of the technique (≈ 20 kb. Applicability of oligonucleotide array-CGH for Preimplantation Genetic Diagnosis has been demonstrated in two cases of Robertsonian translocation carriers 45,XY,der(13;14(q10;q10. Transfer of euploid embryos was performed in both cases and pregnancy was achieved by one of the couples. This is the first time that an oligonucleotide array-CGH approach has been successfully applied to Preimplantation Genetic Diagnosis for balanced chromosome rearrangement carriers.

  2. Oligonucleotide Arrays vs. Metaphase-Comparative Genomic Hybridisation and BAC Arrays for Single-Cell Analysis: First Applications to Preimplantation Genetic Diagnosis for Robertsonian Translocation Carriers

    Science.gov (United States)

    Ramos, Laia; del Rey, Javier; Daina, Gemma; García-Aragonés, Manel; Armengol, Lluís; Fernandez-Encinas, Alba; Parriego, Mònica; Boada, Montserrat; Martinez-Passarell, Olga; Martorell, Maria Rosa; Casagran, Oriol; Benet, Jordi; Navarro, Joaquima

    2014-01-01

    Comprehensive chromosome analysis techniques such as metaphase-Comparative Genomic Hybridisation (CGH) and array-CGH are available for single-cell analysis. However, while metaphase-CGH and BAC array-CGH have been widely used for Preimplantation Genetic Diagnosis, oligonucleotide array-CGH has not been used in an extensive way. A comparison between oligonucleotide array-CGH and metaphase-CGH has been performed analysing 15 single fibroblasts from aneuploid cell-lines and 18 single blastomeres from human cleavage-stage embryos. Afterwards, oligonucleotide array-CGH and BAC array-CGH were also compared analysing 16 single blastomeres from human cleavage-stage embryos. All three comprehensive analysis techniques provided broadly similar cytogenetic profiles; however, non-identical profiles appeared when extensive aneuploidies were present in a cell. Both array techniques provided an optimised analysis procedure and a higher resolution than metaphase-CGH. Moreover, oligonucleotide array-CGH was able to define extra segmental imbalances in 14.7% of the blastomeres and it better determined the specific unbalanced chromosome regions due to a higher resolution of the technique (≈20 kb). Applicability of oligonucleotide array-CGH for Preimplantation Genetic Diagnosis has been demonstrated in two cases of Robertsonian translocation carriers 45,XY,der(13;14)(q10;q10). Transfer of euploid embryos was performed in both cases and pregnancy was achieved by one of the couples. This is the first time that an oligonucleotide array-CGH approach has been successfully applied to Preimplantation Genetic Diagnosis for balanced chromosome rearrangement carriers. PMID:25415307

  3. Fabrication of graphene/titanium carbide nanorod arrays for chemical sensor application

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Chong [Tianjin Key Laboratory of Film Electronic and Communicate Devices, School of Electronics Information Engineering, Tianjin University of Technology, Tianjin 300384 (China); Li, Mingji, E-mail: limingji@163.com [Tianjin Key Laboratory of Film Electronic and Communicate Devices, School of Electronics Information Engineering, Tianjin University of Technology, Tianjin 300384 (China); Li, Hongji, E-mail: hongjili@yeah.net [Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry & Chemical Engineering, Tianjin University of Technology, Tianjin 300384 (China); Li, Cuiping; Qu, Changqing; Yang, Baohe [Tianjin Key Laboratory of Film Electronic and Communicate Devices, School of Electronics Information Engineering, Tianjin University of Technology, Tianjin 300384 (China)

    2017-03-01

    Vertically stacked graphene nanosheet/titanium carbide nanorod array/titanium (graphene/TiC nanorod array) wires were fabricated using a direct current arc plasma jet chemical vapor deposition (DC arc plasma jet CVD) method. The graphene/TiC nanorod arrays were characterized by scanning electron microscopy, transmission electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction spectroscopy. The TiO{sub 2} nanotube array was reduced to the TiC nanorod array, and using those TiC nanorods as nucleation sites, the vertical graphene layer was formed on the TiC nanorod surface. The multi-target response mechanisms of the graphene/TiC nanorod array were investigated for ascorbic acid (AA), dopamine (DA), uric acid (UA), and hydrochlorothiazide (HCTZ). The vertically stacked graphene sheets facilitated the electron transfer and reactant transport with a unique porous surface, high surface area, and high electron transport network of CVD graphene sheets. The TiC nanorod array facilitated the electron transfer and firmly held the graphene layer. Thus, the graphene/TiC nanorod arrays could simultaneously respond to trace biomarkers and antihypertensive drugs. - Highlights: • Vertical graphene sheets were prepared with Ti as the catalyst via a CVD method. • TiO{sub 2} nanotubes were key transition layers in the formation of the TiC nanorods. • Vertical growth mechanism of graphene products was discussed. • Biomolecules were detected to be a chemical sensor. • Response mechanism for analytes at the graphene/TiC nanorod array was discussed.

  4. Fabrication of graphene/titanium carbide nanorod arrays for chemical sensor application

    International Nuclear Information System (INIS)

    Fu, Chong; Li, Mingji; Li, Hongji; Li, Cuiping; Qu, Changqing; Yang, Baohe

    2017-01-01

    Vertically stacked graphene nanosheet/titanium carbide nanorod array/titanium (graphene/TiC nanorod array) wires were fabricated using a direct current arc plasma jet chemical vapor deposition (DC arc plasma jet CVD) method. The graphene/TiC nanorod arrays were characterized by scanning electron microscopy, transmission electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction spectroscopy. The TiO 2 nanotube array was reduced to the TiC nanorod array, and using those TiC nanorods as nucleation sites, the vertical graphene layer was formed on the TiC nanorod surface. The multi-target response mechanisms of the graphene/TiC nanorod array were investigated for ascorbic acid (AA), dopamine (DA), uric acid (UA), and hydrochlorothiazide (HCTZ). The vertically stacked graphene sheets facilitated the electron transfer and reactant transport with a unique porous surface, high surface area, and high electron transport network of CVD graphene sheets. The TiC nanorod array facilitated the electron transfer and firmly held the graphene layer. Thus, the graphene/TiC nanorod arrays could simultaneously respond to trace biomarkers and antihypertensive drugs. - Highlights: • Vertical graphene sheets were prepared with Ti as the catalyst via a CVD method. • TiO 2 nanotubes were key transition layers in the formation of the TiC nanorods. • Vertical growth mechanism of graphene products was discussed. • Biomolecules were detected to be a chemical sensor. • Response mechanism for analytes at the graphene/TiC nanorod array was discussed.

  5. A coherent polarimeter array for the Large Scale Polarization Explorer balloon experiment

    OpenAIRE

    Bersanelli, M.; Mennella, A.; Morgante, G.; Zannoni, M.; Addamo, G.; Baschirotto, A.; Battaglia, P.; Baù, A.; Cappellini, B.; Cavaliere, F.; Cuttaia, F.; Del Torto, F.; Donzelli, S.; Farooqui, Z.; Frailis, M.

    2012-01-01

    We discuss the design and expected performance of STRIP (STRatospheric Italian Polarimeter), an array of coherent receivers designed to fly on board the LSPE (Large Scale Polarization Explorer) balloon experiment. The STRIP focal plane array comprises 49 elements in Q band and 7 elements in W-band using cryogenic HEMT low noise amplifiers and high performance waveguide components. In operation, the array will be cooled to 20 K and placed in the focal plane of a $\\sim 0.6$ meter telescope prov...

  6. Status of LOFAR Data in HDF5 Format

    NARCIS (Netherlands)

    Alexov, A.; Schellart, P.; ter Veen, S.; van den Akker, M.; Bähren, L.; Grießmeier, J.M.; Hessels, J.W.T.; Mol, J.D.; Renting, G.A.; Swinbank, J.; Wise, M.

    2012-01-01

    The Hierarchical Data Format, version 5 (HDF5) is a data model, library, and file format for storing and managing data. It is designed for flexible and efficient I/O and for high volume, complex data. The Low Frequency Array (LOFAR) project is solving the challenge of data size and complexity using

  7. APD arrays and large-area APDs via a new planar process

    CERN Document Server

    Farrell, R; Vanderpuye, K; Grazioso, R; Myers, R; Entine, G

    2000-01-01

    A fabrication process has been developed which allows the beveled-edge-type of avalanche photodiode (APD) to be made without the need for the artful bevel formation steps. This new process, applicable to both APD arrays and to discrete detectors, greatly simplifies manufacture and should lead to significant cost reduction for such photodetectors. This is achieved through a simple innovation that allows isolation around the device or array pixel to be brought into the plane of the surface of the silicon wafer, hence a planar process. A description of the new process is presented along with performance data for a variety of APD device and array configurations. APD array pixel gains in excess of 10 000 have been measured. Array pixel coincidence timing resolution of less than 5 ns has been demonstrated. An energy resolution of 6% for 662 keV gamma-rays using a CsI(T1) scintillator on a planar processed large-area APD has been recorded. Discrete APDs with active areas up to 13 cm sup 2 have been operated.

  8. Ultra-wideband WDM VCSEL arrays by lateral heterogeneous integration

    Science.gov (United States)

    Geske, Jon

    Advancements in heterogeneous integration are a driving factor in the development of evermore sophisticated and functional electronic and photonic devices. Such advancements will merge the optical and electronic capabilities of different material systems onto a common integrated device platform. This thesis presents a new lateral heterogeneous integration technology called nonplanar wafer bonding. The technique is capable of integrating multiple dissimilar semiconductor device structures on the surface of a substrate in a single wafer bond step, leaving different integrated device structures adjacent to each other on the wafer surface. Material characterization and numerical simulations confirm that the material quality is not compromised during the process. Nonplanar wafer bonding is used to fabricate ultra-wideband wavelength division multiplexed (WDM) vertical-cavity surface-emitting laser (VCSEL) arrays. The optically-pumped VCSEL arrays span 140 nm from 1470 to 1610 nm, a record wavelength span for devices operating in this wavelength range. The array uses eight wavelength channels to span the 140 nm with all channels separated by precisely 20 nm. All channels in the array operate single mode to at least 65°C with output power uniformity of +/- 1 dB. The ultra-wideband WDM VCSEL arrays are a significant first step toward the development of a single-chip source for optical networks based on coarse WDM (CWDM), a low-cost alternative to traditional dense WDM. The CWDM VCSEL arrays make use of fully-oxidized distributed Bragg reflectors (DBRs) to provide the wideband reflectivity required for optical feedback and lasing across 140 rim. In addition, a novel optically-pumped active region design is presented. It is demonstrated, with an analytical model and experimental results, that the new active-region design significantly improves the carrier uniformity in the quantum wells and results in a 50% lasing threshold reduction and a 20°C improvement in the peak

  9. Investigating the Trade-Off Between Power Generation and Environmental Impact of Tidal-Turbine Arrays Using Array Layout Optimisation and Habitat Sustainability Modelling.

    Science.gov (United States)

    du Feu, R. J.; Funke, S. W.; Kramer, S. C.; Hill, J.; Piggott, M. D.

    2016-12-01

    studied, a range of array formations is found expressing varying preferences for either functional. Further analyses then allow for the identification of trade-offs between the two key societal objectives of energy production and conservation. This in turn produces information valuable to stakeholders and policymakers when making decisions on array design.

  10. Extending the frequency range of free-field reciprocity calibration of measurement microphones to frequencies up to 150 kHz

    DEFF Research Database (Denmark)

    Barrera Figueroa, Salvador; Torras Rosell, Antoni; Jacobsen, Finn

    2013-01-01

    Measurement microphones are typically calibrated in a free field at frequencies up to 50 kHz. This is a sufficiently high frequency for the most sound measurement applications related with noise assessment. However, other applications such as the measurement of noise emitted by ultrasound cleanin...

  11. Transition-edge sensor imaging arrays for astrophysics applications

    Science.gov (United States)

    Burney, Jennifer Anne

    Many interesting objects in our universe currently elude observation in the optical band: they are too faint or they vary rapidly and thus any structure in their radiation is lost over the period of an exposure. Conventional photon detectors cannot simultaneously provide energy resolution and time-stamping of individual photons at fast rates. Superconducting detectors have recently made the possibility of simultaneous photon counting, imaging, and energy resolution a reality. Our research group has pioneered the use of one such detector, the Transition-Edge Sensor (TES). TES physics is simple and elegant. A thin superconducting film, biased at its critical temperature, can act as a particle detector: an incident particle deposits energy and drives the film into its superconducting-normal transition. By inductively coupling the detector to a SQUID amplifier circuit, this resistance change can be read out as a current pulse, and its energy deduced by integrating over the pulse. TESs can be used to accurately time-stamp (to 0.1 [mu]s) and energy-resolve (0.15 eV at 1.6 eV) near-IR/visible/near-UV photons at rates of 30~kHz. The first astronomical observations using fiber-coupled detectors were made at the Stanford Student Observatory 0.6~m telescope in 1999. Further observations of the Crab Pulsar from the 107" telescope at the University of Texas McDonald Observatory showed rapid phase variations over the near-IR/visible/near-UV band. These preliminary observations provided a glimpse into a new realm of observations of pulsars, binary systems, and accreting black holes promised by TES arrays. This thesis describes the development, characterization, and preliminary use of the first camera system based on Transition-Edge Sensors. While single-device operation is relatively well-understood, the operation of a full imaging array poses significant challenges. This thesis addresses all aspects related to the creation and characterization of this cryogenic imaging

  12. Microelectrode array fabrication for electrochemical detection with carbon nanotubes

    Science.gov (United States)

    Clark, James

    Understanding how the brain works remains one of the key challenges for scientists. To further this understanding a wide variety of technologies and research methods have been developed. One such technology is conductive electrodes, used to measure the electrical signals elicited from neuronal cells and tissues. These electrodes can be fabricated as a singular electrode or as a multi-electrode array (MEA). This permits bio-electrical measurements from one particular area or simultaneous measurements from multiple areas, respectively. Studying electrical and chemical signals of individual cells in situ requires the use of electrodes with ≤20 µm diameter. However, electrodes of this size generally produce high impedance, perturbing recording of the small signals generated from individual cells. Nanomaterials, such as carbon nanotubes (CNTs), can be deposited to increase the real surface area of these electrodes, producing higher sensitivity measurements. This thesis investigates the potential for using photo-thermal chemical vapour deposition grown CNTs as the electrode material for a de novo fabricated MEA. This device aimed to measure electrochemical signals in the form of dopamine, an important mammalian neurotransmitter, as well as conventional bio-electrical signals that the device is designed for. Realising this aim began with improving CNT aqueous wetting behaviour via oxygen plasma functionalisation. This procedure demonstrated grafting of oxygen functional groups to the CNT structure, and dramatic improvements in aqueous wetting behaviour, with CNTs attached to the device. Subsequently, oxygen plasma functionalised CNT-based MEAs were fabricated and tested, allowing comparisons with a non-functionalised CNT MEA and a state-of-the-art commercial MEA. The functionalised CNT MEA demonstrated an order of magnitude improvement compared to commercial MEAs (2.75 kΩ vs. 25.6 kΩ), at the biologically relevant frequency of 1 kHz. This was followed by measurement

  13. Reverse Phase Protein Arrays for High-Throughput Protein Measurements in Mammospheres

    DEFF Research Database (Denmark)

    Pedersen, Marlene Lemvig; Block, Ines; List, Markus

    Protein Array (RPPA)-based readout format integrated into robotic siRNA screening. This technique would allow post-screening high-throughput quantification of protein changes. Recently, breast cancer stem cells (BCSCs) have attracted much attention, as a tumor- and metastasis-driving subpopulation...

  14. Two's complement array multiplier using true values of the operands

    Energy Technology Data Exchange (ETDEWEB)

    Bandeira, N.; Voccaro, K.; Howard, J.A.

    1983-08-01

    A new algorithm for implementing the two's complement multiplication of an m*n bit number is described. By interpreting certain positive partial product bits as negative, a parallel array is developed which has the advantage of using only one type of adder cell. A comparison with the Pezaris and Baugh-Wooley arrays is presented, showing that the new array is as fast as the Pezaris array and uses less hardware than the Baugh-Wooley implementation (see S.D. Pezaris ibid., vol.C-20, p.442-7, 1971, and C.R. Baugh and B.A. Wooley, ibid., vol.C22, p.1045-7, 1973). 18 references.

  15. Analysis of X-ray iron and nickel radiation and jets from planar wire arrays and X-pinches

    International Nuclear Information System (INIS)

    Safronova, A S; Kantsyrev, V L; Esaulov, A A; Ouart, N D; Shlyaptseva, V; Williamson, K M; Shrestha, I; Osborne, G C; Weller, M E

    2010-01-01

    University-scale Z-pinch devices are able to produce plasmas with a broad range of sizes, temperatures, densities, their gradients, and opacity properties. Radiative properties of such plasmas depend on material, mass, and configuration of the wire array loads. Experiments with two different types of loads, double planar wire arrays (DPWA) and X-pinches, performed on the 1 MA Zebra generator at UNR are analyzed. X-pinches are made from Stainless Steel (69% Fe, 20% Cr, and 9% Ni) wires. Combined DPWAs consist of one plane from SS wires and another plane from Alumel (95% Ni, 2% Al, 2% Si) wires. The main focus of this work is on the analysis of plasma jets at the early phase of plasma formation and the K-and L-shell radiation generation at the implosion and stagnation phases in experiments with the two aforementioned wire loads. The relevant theoretical tools that guide the data analysis include non-LTE collisional-radiative and wire ablation dynamics models. The astrophysical relevance of the plasma jets as well as of spectroscopic and imaging studies are demonstrated.

  16. High-speed imaging at high x-ray energy: CdTe sensors coupled to charge-integrating pixel array detectors

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Julian; Tate, Mark W.; Shanks, Katherine S.; Philipp, Hugh T.; Weiss, Joel T.; Purohit, Prafull [Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, NY 14853 (United States); Chamberlain, Darol [Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, NY 14853 (United States); Gruner, Sol M., E-mail: smg26@cornell.edu [Laboratory of Atomic and Solid State Physics, Cornell University, Ithaca, NY 14853 (United States); Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, NY 14853 (United States)

    2016-07-27

    Pixel Array Detectors (PADs) consist of an x-ray sensor layer bonded pixel-by-pixel to an underlying readout chip. This approach allows both the sensor and the custom pixel electronics to be tailored independently to best match the x-ray imaging requirements. Here we describe the hybridization of CdTe sensors to two different charge-integrating readout chips, the Keck PAD and the Mixed-Mode PAD (MM-PAD), both developed previously in our laboratory. The charge-integrating architecture of each of these PADs extends the instantaneous counting rate by many orders of magnitude beyond that obtainable with photon counting architectures. The Keck PAD chip consists of rapid, 8-frame, in-pixel storage elements with framing periods <150 ns. The second detector, the MM-PAD, has an extended dynamic range by utilizing an in-pixel overflow counter coupled with charge removal circuitry activated at each overflow. This allows the recording of signals from the single-photon level to tens of millions of x-rays/pixel/frame while framing at 1 kHz. Both detector chips consist of a 128×128 pixel array with (150 µm){sup 2} pixels.

  17. High Discharge Energy Density at Low Electric Field Using an Aligned Titanium Dioxide/Lead Zirconate Titanate Nanowire Array.

    Science.gov (United States)

    Zhang, Dou; Liu, Weiwei; Guo, Ru; Zhou, Kechao; Luo, Hang

    2018-02-01

    Polymer-based capacitors with high energy density have attracted significant attention in recent years due to their wide range of potential applications in electronic devices. However, the obtained high energy density is predominantly dependent on high applied electric field, e.g., 400-600 kV mm -1 , which may bring more challenges relating to the failure probability. Here, a simple two-step method for synthesizing titanium dioxide/lead zirconate titanate nanowire arrays is exploited and a demonstration of their ability to achieve high discharge energy density capacitors for low operating voltage applications is provided. A high discharge energy density of 6.9 J cm -3 is achieved at low electric fields, i.e., 143 kV mm -1 , which is attributed to the high relative permittivity of 218.9 at 1 kHz and high polarization of 23.35 µC cm -2 at this electric field. The discharge energy density obtained in this work is the highest known for a ceramic/polymer nanocomposite at such a low electric field. The novel nanowire arrays used in this work are applicable to a wide range of fields, such as energy harvesting, energy storage, and photocatalysis.

  18. Simple and robust phase-locking of optical cavities with > 200 KHz servo-bandwidth using a piezo-actuated mirror mounted in soft materials.

    Science.gov (United States)

    Goldovsky, David; Jouravsky, Valery; Pe'er, Avi

    2016-12-12

    We present an approach to locking of optical cavities with piezoelectric actuated mirrors based on a simple and effective mechanical decoupling of the mirror and actuator from the surrounding mount. Using simple elastic materials (e.g. rubber or soft silicone gel pads) as mechanical dampers between the piezo-mirror compound and the surrounding mount, a firm and stable mounting of a relatively large mirror (8mm diameter) can be maintained that is isolated from external mechanical resonances, and is limited only by the internal piezo-mirror resonance of > 330 KHz. Our piezo lock showed positive servo gain up to 208 KHz, and a temporal response to a step interference within < 3 μs.

  19. A colorimetric sensor array for identification of toxic gases below permissible exposure limits†

    OpenAIRE

    Feng, Liang; Musto, Christopher J.; Kemling, Jonathan W.; Lim, Sung H.; Suslick, Kenneth S.

    2010-01-01

    A colorimetric sensor array has been developed for the rapid and sensitive detection of 20 toxic industrial chemicals (TICs) at their PELs (permissible exposure limits). The color changes in an array of chemically responsive nanoporous pigments provide facile identification of the TICs with an error rate below 0.7%.

  20. Pro-social 50-kHz ultrasonic communication in rats: post-weaning but not post-adolescent social isolation leads to social impairments—phenotypic rescue by re-socialization

    Science.gov (United States)

    Seffer, Dominik; Rippberger, Henrike; Schwarting, Rainer K. W.; Wöhr, Markus

    2015-01-01

    Rats are highly social animals and social play during adolescence has an important role for social development, hence post-weaning social isolation is widely used to study the adverse effects of juvenile social deprivation and to induce behavioral phenotypes relevant to neuropsychiatric disorders, like schizophrenia. Communication is an important component of the rat's social behavior repertoire, with ultrasonic vocalizations (USV) serving as situation-dependent affective signals. High-frequency 50-kHz USV occur in appetitive situations and induce approach behavior, supporting the notion that they serve as social contact calls; however, post-weaning isolation effects on the behavioral changes displayed by the receiver in response to USV have yet to be studied. We therefore investigated the impact of post-weaning isolation on socio-affective information processing as assessed by means of our established 50-kHz USV radial maze playback paradigm. We showed that post-weaning social isolation specifically affected the behavioral response to playback of pro-social 50-kHz but not alarm 22-kHz USV. While group-housed rats showed the expected preference, i.e., approach, toward 50-kHz USV, the response was even stronger in short-term isolated rats (i.e., 1 day), possibly due to a higher level of social motivation. In contrast, no approach was observed in long-term isolated rats (i.e., 4 weeks). Importantly, deficits in approach were reversed by peer-mediated re-socialization and could not be observed after post-adolescent social isolation, indicating a critical period for social development during adolescence. Together, these results highlight the importance of social experience for affiliative behavior, suggesting a critical involvement of play behavior on socio-affective information processing in rats. PMID:25983681

  1. Design of a new electrode array for cochlear implants

    International Nuclear Information System (INIS)

    Kha, H.; Chen, B.

    2010-01-01

    Full text: This study aims to design a new electrode array which can be precisely located beneath the basilar membrane within the cochlear scala tympani. This placement of the electrode array is beneficial for increasing the effectiveness of the electrical stimulation of the audi tory nerves and maximising the growth factors delivered into the cochlea for regenerating the progressively lost auditory neurons, thereby significantly improving performance of the cochlear implant systems. Methods The design process involved two steps. First, the biocom patible nitinol-based shape memory alloy, of which mechanical deformation can be controlled using electrical cUTents/fields act vated by body temperature, was selected. Second, five different designs of the electrode array with embedded nitinol actuators were studied (Table I). The finite element method was employed to predict final positions of these electrode arrays. Results The electrode array with three 6 mm actuators at 2-8, 8-J4 and 14-20 mm from the tip (Fig. I) was found to be located most closely to the basilar membrane, compared with those in the other four cases. Conclusions A new nitinol cochlear implant electrode array with three embedded nitinol actuators has been designed. This electrode array is expected to be located beneath the basilar membrane for maximising the delivery of growth factors. Future research will involve the manufacturing of a prototype of this electrode array for use in insertion experiments and neurotrophin release tests.

  2. Globally Stable Microresonator Turing Pattern Formation for Coherent High-Power THz Radiation On-Chip

    Science.gov (United States)

    Huang, Shu-Wei; Yang, Jinghui; Yang, Shang-Hua; Yu, Mingbin; Kwong, Dim-Lee; Zelevinsky, T.; Jarrahi, Mona; Wong, Chee Wei

    2017-10-01

    In nonlinear microresonators driven by continuous-wave (cw) lasers, Turing patterns have been studied in the formalism of the Lugiato-Lefever equation with emphasis on their high coherence and exceptional robustness against perturbations. Destabilization of Turing patterns and the transition to spatiotemporal chaos, however, limit the available energy carried in the Turing rolls and prevent further harvest of their high coherence and robustness to noise. Here, we report a novel scheme to circumvent such destabilization, by incorporating the effect of local mode hybridizations, and we attain globally stable Turing pattern formation in chip-scale nonlinear oscillators with significantly enlarged parameter space, achieving a record-high power-conversion efficiency of 45% and an elevated peak-to-valley contrast of 100. The stationary Turing pattern is discretely tunable across 430 GHz on a THz carrier, with a fractional frequency sideband nonuniformity measured at 7.3 ×10-14 . We demonstrate the simultaneous microwave and optical coherence of the Turing rolls at different evolution stages through ultrafast optical correlation techniques. The free-running Turing-roll coherence, 9 kHz in 200 ms and 160 kHz in 20 minutes, is transferred onto a plasmonic photomixer for one of the highest-power THz coherent generations at room temperature, with 1.1% optical-to-THz power conversion. Its long-term stability can be further improved by more than 2 orders of magnitude, reaching an Allan deviation of 6 ×10-10 at 100 s, with a simple computer-aided slow feedback control. The demonstrated on-chip coherent high-power Turing-THz system is promising to find applications in astrophysics, medical imaging, and wireless communications.

  3. 200 kHz Sonication of Mixed-Algae Suspension from a Eutrophic Lake: The Effect on the Caution vs. Outbreak Bloom Alert Levels

    Directory of Open Access Journals (Sweden)

    Andinet Tekile

    2017-11-01

    Full Text Available For effective ultrasonic algae removal, several studies have considered the ultrasound equipment linked factors, such as power and frequency. However, studies on the response of mixed algal cultures and associated water quality parameters to ultrasound are limited. In this lab-scale sonication, the removal of cyanobacteria at a pre-set frequency of 200 kHz on mixed algae suspensions collected from a eutrophic lake was investigated. The caution (17.5 µg/L and outbreak (1450 µg/L alert levels in terms of chlorophyll-a (Chl-a concentrations of the initial samples were each sonicated for 10, 15, and 20 min, and then kept in an incubator. Fifteen minutes of sonication resulted in best removal efficiency of 0.94 and 0.77, at an ultrasonic dose of 30 kWh/m3 at the outbreak and caution level concentrations, respectively. Immediately after 15 min sonication, and after standing in the incubator for a day, chlorophyll-a removal efficiencies of 0.28 and 0.90 were achieved in the outbreak level, respectively, and the matching removal efficiencies for the caution level were 0.23 and 0.64. Even though the removal was substantial in both cases, the final 147 µg/L chlorophyll-a concentration of the outbreak, which is itself still in the outbreak level range, shows that ultrasonication is not effective to satisfactorily remove algae from a concentrated suspension. Total dissolved nitrogen and chemical oxygen demand were reduced, overall, due to sonication. However, total dissolved phosphorus of the concentrated level was increased during the treatment. Although sonication needs further replicated experimental testing in whole-lake systems, our results show that 200 kHz sonication was able to reduce chlorophyll-a concentrations in small-scale laboratory tests.

  4. Fabrication of Slanted Cu Nanopillars with Uniform Arrays

    Directory of Open Access Journals (Sweden)

    Sung-Woon Cho

    2016-02-01

    Full Text Available Slanted Cu nanopillars with uniform arrays were fabricat‐ ed using slanted Si channel structures as templates. A slanted plasma etching technique was employed, utilizing a Faraday cage system for the formation of these slanted channel structures. The angle of the slanted channel structures was accurately controlled because ions entering the Faraday cage maintained their direction. After the slanted channel structures were formed, they were filled with Cu by electroless deposition. Chemical mechanical polishing was then used to remove the excess Cu film and the SiO2 masks. Finally, the remaining poly Si of the channel structures was removed by wet chemical etching. This work offers a novel method for the fabrication of slanted metal nanostructures with uniform arrays covering a large area.

  5. The Pierre Auger Research and Development Array (RDA in southeastern Colorado – R&D for a giant ground array

    Directory of Open Access Journals (Sweden)

    Thompson J.

    2013-06-01

    Full Text Available The Pierre Auger Research and Development Array (RDA was originally designed to be the precursor of the northern Auger observatory, a hybrid array of 4400 surface detector stations and 39 fluorescence telescopes deployed over 20,000 square kilometers. It is conceived as a test bed aiming at validating an improved and more cost-effective 1-PMT surface detector design and a new peer-to-peer communication system. The array of ten surface detector stations and ten communication-only stations is currently being deployed in southeastern Colorado and will be operated at least until late 2013. It is configured in such a way that it allows testing of a new peer-to-peer communication protocol, as well as a new surface detector electronics design with a larger dynamic range aiming at reducing the distance from the shower core where saturation is observed. All these developments are expected in the short term to improve the performance of the Pierre Auger Observatory and enable future enhancements. In the longer term, it is hoped that some of these new developments may contribute to the design of a next-generation giant ground array.

  6. Equation of State Dependent Dynamics and Multi-messenger Signals from Stellar-mass Black Hole Formation

    Science.gov (United States)

    Pan, Kuo-Chuan; Liebendörfer, Matthias; Couch, Sean M.; Thielemann, Friedrich-Karl

    2018-04-01

    We investigate axisymmetric black hole (BH) formation and its gravitational wave (GW) and neutrino signals with self-consistent core-collapse supernova simulations of a non-rotating 40 M ⊙ progenitor star using the isotropic diffusion source approximation for the neutrino transport and a modified gravitational potential for general relativistic effects. We consider four different neutron star (NS) equations of state (EoS): LS220, SFHo, BHBΛϕ, and DD2, and study the impact of the EoS on BH formation dynamics and GW emission. We find that the BH formation time is sensitive to the EoS from 460 to >1300 ms and is delayed in multiple dimensions for ∼100–250 ms due to the finite entropy effects. Depending on the EoS, our simulations show the possibility that shock revival can occur along with the collapse of the proto-neutron star (PNS) to a BH. The gravitational waveforms contain four major features that are similar to previous studies but show extreme values: (1) a low-frequency signal (∼300–500 Hz) from core-bounce and prompt convection, (2) a strong signal from the PNS g-mode oscillation among other features, (3) a high-frequency signal from the PNS inner-core convection, and (4) signals from the standing accretion shock instability and convection. The peak frequency at the onset of BH formation reaches to ∼2.3 kHz. The characteristic amplitude of a 10 kpc object at peak frequency is detectable but close to the noise threshold of the Advanced LIGO and KAGRA, suggesting that the next-generation GW detector will need to improve the sensitivity at the kHz domain to better observe stellar-mass BH formation from core-collapse supernovae or failed supernovae.

  7. Rapid recognition of volatile organic compounds with colorimetric sensor arrays for lung cancer screening.

    Science.gov (United States)

    Zhong, Xianhua; Li, Dan; Du, Wei; Yan, Mengqiu; Wang, You; Huo, Danqun; Hou, Changjun

    2018-06-01

    Volatile organic compounds (VOCs) in breath can be used as biomarkers to identify early stages of lung cancer. Herein, we report a disposable colorimetric array that has been constructed from diverse chemo-responsive colorants. Distinguishable difference maps were plotted within 4 min for specifically targeted VOCs. Through the consideration of various chemical interactions with VOCs, the arrays successfully discriminate between 20 different volatile organic compounds in breath that are related to lung cancer. VOCs were identified either with the visualized difference maps or through pattern recognition with an accuracy of at least 90%. No uncertainties or errors were observed in the hierarchical cluster analysis (HCA). Finally, good reproducibility and stability of the array was achieved against changes in humidity. Generally, this work provides fundamental support for construction of simple and rapid VOC sensors. More importantly, this approach provides a hypothesis-free array method for breath testing via VOC profiling. Therefore, this small, rapid, non-invasive, inexpensive, and visualized sensor array is a powerful and promising tool for early screening of lung cancer. Graphical abstract A disposable colorimetric array has been developed with broadly chemo-responsive dyes to incorporate various chemical interactions, through which the arrays successfully discriminate 20 VOCs that are related to lung cancer via difference maps alone or chemometrics within 4 min. The hydrophobic porous matrix provides good stability against changes in humidity.

  8. A Next Generation Light Source Facility at LBNL

    Energy Technology Data Exchange (ETDEWEB)

    Corlett, J.N.; Austin, B.; Baptiste, K.M.; Byrd, J.M.; Denes, P.; Donahue, R.; Doolittle, L.; Falcone, R.W.; Filippetto, D.; Fournier, S.; Li, D.; Padmore, H.A.; Papadopoulos, C.; Pappas, C.; Penn, G.; Placidi, M.; Prestemon, S.; Prosnitz, D.; Qiang, J.; Ratti, A.; Reinsch, M.; Sannibale, F.; Schlueter, R.; Schoenlein, R.W.; Staples, J.W.; Vecchione, T.; Venturini, M.; Wells, R.; Wilcox, R.; Wurtele, J.; Charman, A.; Kur, E.; Zholents, A.A.

    2011-03-23

    The Next Generation Light Source (NGLS) is a design concept, under development at LBNL, for a multibeamline soft x-ray FEL array powered by a ~;;2 GeV superconducting linear accelerator, operating with a 1 MHz bunch repetition rate. The CW superconducting linear accelerator is supplied by a high-brightness, highrepetition- rate photocathode electron gun. Electron bunches are distributed from the linac to the array of independently configurable FEL beamlines with nominal bunch rates up to 100 kHz in each FEL, and with even pulse spacing. Individual FELs may be configured for EEHG, HGHG, SASE, or oscillator mode of operation, and will produce high peak and average brightness x-rays with a flexible pulse format, with pulse durations ranging from sub-femtoseconds to hundreds of femtoseconds.

  9. MEMS-Based Solid Propellant Rocket Array Thruster

    Science.gov (United States)

    Tanaka, Shuji; Hosokawa, Ryuichiro; Tokudome, Shin-Ichiro; Hori, Keiichi; Saito, Hirobumi; Watanabe, Masashi; Esashi, Masayoshi

    The prototype of a solid propellant rocket array thruster for simple attitude control of a 10 kg class micro-spacecraft was completed and tested. The prototype has 10×10 φ0.8 mm solid propellant micro-rockets arrayed at a pitch of 1.2 mm on a 20×22 mm substrate. To realize such a dense array of micro-rockets, each ignition heater is powered from the backside of the thruster through an electrical feedthrough which passes along a propellant cylinder wall. Boron/potassium nitrate propellant (NAB) is used with/without lead rhodanide/potassium chlorate/nitrocellulose ignition aid (RK). Impulse thrust was measured by a pendulum method in air. Ignition required electric power of at least 3 4 W with RK and 4 6 W without RK. Measured impulse thrusts were from 2×10-5 Ns to 3×10-4 Ns after the calculation of compensation for air dumping.

  10. Network centrality based team formation: A case study on T-20 cricket

    Directory of Open Access Journals (Sweden)

    Paramita Dey

    2017-07-01

    Full Text Available This paper proposes and evaluates the novel utilization of small world network properties for the formation of team of players with both best performances and best belongingness within the team network. To verify this concept, this methodology is applied to T-20 cricket teams. The players are treated as nodes of the network, whereas the number of interactions between team members is denoted as the edges between those nodes. All intra country networks form the cricket network for this case study. Analysis of the networks depicts that T-20 cricket network inherits all characteristics of small world network. Making a quantitative measure for an individual performance in the team sports is important with respect to the fact that for team selection of an International match, from pool of best players, only eleven players can be selected for the team. The statistical record of each player considered as a traditional way of quantifying the performance of a player. But the other criteria such as performing against a strong opponent or performance as an effective team member such as fielding, running between the wickets, good partnership deserves more credential. In this paper a revised method based on social networking is presented to quantify the quality of team belongingness and efficiency of each player. The application of Social Network Analysis (SNA is explored to measure performances and the rank of the players. A bidirectional weighted network of players is generated using the information collected from T-20 cricket (2014–2016 and used for network analysis. Thus team was formed based on that ranking and compared with their IPL (Indian Premier League performances of 2016.

  11. Characterization of a large-format, fine-pitch CdZnTe pixel detector for the HEFT balloon-Borne experiment

    OpenAIRE

    Chen, C. M. Hubert; Cook, Walter R.; Harrison, Fiona A.; Lin, Jiao Y. Y.

    2004-01-01

    We have developed a large-format CdZnTe pixel detector with custom, low-noise ASIC readout, for astrophysical applications. In particular, this detector is targeted for use in the High-Energy Focusing Telescope (HEFT), a balloon-borne experiment with focusing optics for 20-70 keV. The detector is a 24 X 44 pixel array of 498-µm pitch. As a focal plane detector, uniformity from pixel to pixel is very desirable. In this paper, we present the characterization of some detector properties for the ...

  12. Sperm whales reduce foraging effort during exposure to 1-2 kHz sonar and killer whale sounds.

    Science.gov (United States)

    Isojunno, Saana; Cure, Charlotte; Kvadsheim, Petter Helgevold; Lam, Frans-Peter Alexander; Tyack, Peter Lloyd; Wensveen, Paul Jacobus; Miller, Patrick James O'Malley

    2016-01-01

    The time and energetic costs of behavioral responses to incidental and experimental sonar exposures, as well as control stimuli, were quantified using hidden state analysis of time series of acoustic and movement data recorded by tags (DTAG) attached to 12 sperm whales (Physeter macrocephalus) using suction cups. Behavioral state transition modeling showed that tagged whales switched to a non-foraging, non-resting state during both experimental transmissions of low-frequency active sonar from an approaching vessel (LFAS; 1-2 kHz, source level 214 dB re 1 µPa m, four tag records) and playbacks of potential predator (killer whale, Orcinus orca) sounds broadcast at naturally occurring sound levels as a positive control from a drifting boat (five tag records). Time spent in foraging states and the probability of prey capture attempts were reduced during these two types of exposures with little change in overall locomotion activity, suggesting an effect on energy intake with no immediate compensation. Whales switched to the active non-foraging state over received sound pressure levels of 131-165 dB re 1 µPa during LFAS exposure. In contrast, no changes in foraging behavior were detected in response to experimental negative controls (no-sonar ship approach or noise control playback) or to experimental medium-frequency active sonar exposures (MFAS; 6-7 kHz, source level 199 re 1 µPa m, received sound pressure level [SPL] = 73-158 dB re 1 µPa). Similarly, there was no reduction in foraging effort for three whales exposed to incidental, unidentified 4.7-5.1 kHz sonar signals received at lower levels (SPL = 89-133 dB re 1 µPa). These results demonstrate that similar to predation risk, exposure to sonar can affect functional behaviors, and indicate that increased perception of risk with higher source level or lower frequency may modulate how sperm whales respond to anthropogenic sound.

  13. Wire array z-pinch insights for high X-ray power generation

    International Nuclear Information System (INIS)

    Sanford, T.W.L.; Marder, B.M.; Desjarlais, M.P.

    1998-01-01

    The discovery that the use of very large numbers of wires enables high x-ray power to be generated from wire-array z-pinches represents a breakthrough in load design for large pulsed power generators, and has permitted high temperatures to be generated in radiation cavities on Saturn and Z. In this paper, changes in x-ray emission characteristics as a function of wire number, array mass, and load radius, for 20-mm-long aluminum arrays on Saturn that led to these breakthrough hohlraum results, are discussed and compared with a few related emission characteristics of high-wire-number aluminum and tungsten arrays on Z. X-ray measurement comparisons with analytic models and 2-D radiation-magnetohydrodynamic (RMHC) code simulations in the x-y and r-z planes provide confidence in the ability of the models and codes to predict future x-ray performance with very-large-number wire arrays

  14. Wire array z-pinch insights for high X-ray power generation

    Energy Technology Data Exchange (ETDEWEB)

    Sanford, T.W.L.; Marder, B.M.; Desjarlais, M.P. [and others

    1998-12-31

    The discovery that the use of very large numbers of wires enables high x-ray power to be generated from wire-array z-pinches represents a breakthrough in load design for large pulsed power generators, and has permitted high temperatures to be generated in radiation cavities on Saturn and Z. In this paper, changes in x-ray emission characteristics as a function of wire number, array mass, and load radius, for 20-mm-long aluminum arrays on Saturn that led to these breakthrough hohlraum results, are discussed and compared with a few related emission characteristics of high-wire-number aluminum and tungsten arrays on Z. X-ray measurement comparisons with analytic models and 2-D radiation-magnetohydrodynamic (RMHC) code simulations in the x-y and r-z planes provide confidence in the ability of the models and codes to predict future x-ray performance with very-large-number wire arrays.

  15. Wire array z-pinch insights for high x-ray power generation

    Energy Technology Data Exchange (ETDEWEB)

    Sanford, T.W.L.; Mock, R.C.; Marder, B.M. [and others

    1997-12-31

    The discovery that the use of very large numbers of wires enables high x-ray power to be generated from wire-array z-pinches represents a breakthrough in load design for large pulsed power generators, and has permitted high temperatures to be generated in radiation cavities on Saturn and Z. In this paper, changes in x-ray emission characteristics as a function of wire number, array mass, and load radius, for 20-mm-long aluminum arrays on Saturn that led to these breakthrough hohlraum results, are discussed and compared with a few related emission characteristics of high-wire-number aluminum and tungsten arrays on Z. X-ray measurement comparisons with analytic models and 2-D radiation-magnetohydrodynamic (RMHC) code simulations in the x-y and r-z planes provide confidence in the ability of the models and codes to predict future x-ray performance with very-large-number wire arrays.

  16. Wire array z-pinch insights for high x-ray power generation

    Energy Technology Data Exchange (ETDEWEB)

    Sanford, T.W.L.; Mock, R.C.; Nash, T.J. [and others

    1998-08-01

    The discovery that the use of very large numbers of wires enables high x-ray power to be generated from wire-array z-pinches represents a breakthrough in load design for large pulsed power generators, and has permitted high temperatures to be generated in radiation cavities on Saturn. In this paper, changes in x-ray emission characteristics as a function of wire number, array mass, and load radius, for 20-mm-long aluminum arrays on Saturn that led to these breakthrough hohlraum results, are discussed and compared with a few related emission characteristics of high-wire-number aluminum and tungsten arrays on Z. X=ray measurement comparisons with analytic models and 2-D radiation-magnetohydrodynamic (RMHC) code simulations in the x-y and r-z planes provide confidence in the ability of the models and codes to predict future x-ray performance with very-large-number wire arrays.

  17. Wire array z-pinch insights for high x-ray power generation

    International Nuclear Information System (INIS)

    Sanford, T.W.L.; Mock, R.C.; Marder, B.M.

    1998-08-01

    The discovery that the use of very large numbers of wires enables high x-ray power to be generated from wire-array z-pinches represents a breakthrough in load design for large pulsed power generators, and has permitted high temperatures to be generated in radiation cavities on Saturn and Z. In this paper, changes in x-ray emission characteristics as a function of wire number, array mass, and load radius, for 20-mm-long aluminum arrays on Saturn that led to these breakthrough hohlraum results, are discussed and compared with a few related emission characteristics of high-wire-number aluminum and tungsten arrays on Z. X=ray measurement comparisons with analytic models and 2-D radiation-magnetohydrodynamic (RMHC) code simulations in the x-y and r-z planes provide confidence in the ability of the models and codes to predict future x-ray performance with very-large-number wire arrays

  18. Monolithic Microwave Integrated Circuit (MMIC) Phased Array Demonstrated With ACTS

    Science.gov (United States)

    1996-01-01

    Monolithic Microwave Integrated Circuit (MMIC) arrays developed by the NASA Lewis Research Center and the Air Force Rome Laboratory were demonstrated in aeronautical terminals and in mobile or fixed Earth terminals linked with NASA's Advanced Communications Technology Satellite (ACTS). Four K/Ka-band experimental arrays were demonstrated between May 1994 and May 1995. Each array had GaAs MMIC devices at each radiating element for electronic beam steering and distributed power amplification. The 30-GHz transmit array used in uplinks to ACTS was developed by Lewis and Texas Instruments. The three 20-GHz receive arrays used in downlinks from ACTS were developed in cooperation with the Air Force Rome Laboratory, taking advantage of existing Air Force integrated-circuit, active-phased-array development contracts with the Boeing Company and Lockheed Martin Corporation. Four demonstrations, each related to an application of high interest to both commercial and Department of Defense organizations, were conducted. The location, type of link, and the data rate achieved for each of the applications is shown. In one demonstration-- an aeronautical terminal experiment called AERO-X--a duplex voice link between an aeronautical terminal on the Lewis Learjet and ACTS was achieved. Two others demonstrated duplex voice links (and in one case, interactive video links as well) between ACTS and an Army high-mobility, multipurpose wheeled vehicle (HMMWV, or "humvee"). In the fourth demonstration, the array was on a fixed mount and was electronically steered toward ACTS. Lewis served as project manager for all demonstrations and as overall system integrator. Lewis engineers developed the array system including a controller for open-loop tracking of ACTS during flight and HMMWV motion, as well as a laptop data display and recording system used in all demonstrations. The Jet Propulsion Laboratory supported the AERO-X program, providing elements of the ACTS Mobile Terminal. The successful

  19. Hydrothermal-synthesized NiO nanowall array for lithium ion batteries

    International Nuclear Information System (INIS)

    Yan, Xiaoyan; Tong, Xili; Wang, Jian; Gong, Changwei; Zhang, Mingang; Liang, Liping

    2013-01-01

    Graphical abstract: Freestanding NiO nanowall array is prepared via a hydrothermal synthesis method and shows noticeable Li battery performance with good cycle life and high capacity. Highlights: ► NiO nanowall array is prepared by a hydrothermal synthesis method. ► NiO nanowall array with high capacity as anode material for Li ion battery. ► Nanowall array structure is favorable for fast ion/electron transfer. -- Abstract: We report a self-supported NiO nanowall array prepared by a facile hydrothermal synthesis method. The microstructure and morphology of the sample are characterized by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The hydrothermal-synthesized NiO nanowalls with thicknesses of ∼20 nm arrange vertically to the substrate forming a net-like nanowall array structure. As anode material for lithium ion batteries, the NiO nanowall array exhibits better electrochemical performances with higher coulombic efficiency and better cycling performance as compared to the dense NiO film. The NiO nanowall array shows an initial coulombic efficiency of 76%, as well as good cycling stability with a capacity of 567 mAh g −1 at 0.3 A g −1 after 50 cycles, higher than those of the dense polycrystalline NiO film (361 mAh g −1 ). The superior electrochemical performance is mainly due to the unique nanowall array structure with shorter diffusion length for mass and charge transport

  20. An HDF5-based framework for the distribution and analysis of ultrasonic concrete data

    Science.gov (United States)

    Prince, Luke; Clayton, Dwight; Santos-Villalobos, Hector

    2017-02-01

    There are many commercial ultrasonic tomography devices (UTDs) available for use in nondestructive evaluation (NDE) of reinforced concrete structures. These devices emit, measure, and store ultrasonic signals typically in the 25 kHz to 5 MHz frequency range. UTDs are characterized by a composition of multiple transducers, also known as a transducer array or phased array. Often, UTDs data are in a proprietary format. Consequently, NDE research data is limited to those who have prior non-disclosure agreements or the appropriate licenses. Thus, there is a need for a proper universal data framework to exist such that proprietary file datasets for different concrete specimens can be converted, organized, and stored with relative metadata for individual or collaborative NDE research. Building upon the Hierarchical Data Format (HDF5) model, we have developed a UTD data management framework and Graphic User Interface (GUI) to promote the algorithmic reconstruction of ultrasonic data in a controlled environment for easily reproducible and publishable results.

  1. Preparation and elementary research on electrocatalytic hydrogen evolution of highly ordered titanium dioxide nanotube arrays

    International Nuclear Information System (INIS)

    Wu Qinglong; Liao Junsheng; Bai Yun

    2010-01-01

    Well ordered and uniform titanium dioxide nanotube arrays were fabricated by anodiaing process from a bath containing 1% NaF, 1mol/L Na 2 SO 4 , 0.5 mol/L H 2 SO 4 at room temperature. Surface morphology of titanium dioxide nanotube arrays were observed with SEM. The formation process of titanium dioxide nanotube arrays was suggested by current-time transient. Its catalytic hydrogen evolution behavior was studied by electrochemical measurements in a 5%(mass fraction) H 2 SO 4 solution. The results showed that the titanium dioxide nanotube arrays on titanium had better hydrogen evolution activity and trace palladium lead to the maximum electrocatalytic activity of hydrogen production. (authors)

  2. A novel, flat, electronically-steered phased array transducer for tissue ablation: preliminary results

    International Nuclear Information System (INIS)

    Ellens, Nicholas P K; Lucht, Benjamin B C; Gunaseelan, Samuel T; Hudson, John M; Hynynen, Kullervo H

    2015-01-01

    Flat, λ/2-spaced phased arrays for therapeutic ultrasound were examined in silico and in vitro. All arrays were made by combining modules made of 64 square elements with 1.5 mm inter-element spacing along both major axes. The arrays were designed to accommodate integrated, co-aligned diagnostic transducers for targeting and monitoring. Six arrays of 1024 elements (16 modules) and four arrays of 6144 elements (96 modules) were modelled and compared according to metrics such as peak pressure amplitude, focal size, ability to be electronically-steered far off-axis and grating lobe amplitude. Two 1024 element prototypes were built and measured in vitro, producing over 100 W of acoustic power. In both cases, the simulation model of the pressure amplitude field was in good agreement with values measured by hydrophone. Using one of the arrays, it was shown that the peak pressure amplitude dropped by only 24% and 25% of the on-axis peak pressure amplitude when steered to the edge of the array (40 mm) at depths of 30 mm and 50 mm. For the 6144 element arrays studied in in silico only, similarly high steerability was found: even when steered 100 mm off-axis, the pressure amplitude decrease at the focus was less than 20%, while the maximum pressure grating lobe was only 20%. Thermal simulations indicate that the modules produce more than enough acoustic power to perform rapid ablations at physiologically relevant depths and steering angles. Arrays such as proposed and tested in this study have enormous potential: their high electronic steerability suggests that they will be able to perform ablations of large volumes without the need for any mechanical translation. (paper)

  3. Single and nested tungsten-wire-array dynamics and applications to inertial confinement fusion

    Science.gov (United States)

    Cuneo, Michael

    2005-10-01

    Wire array z-pinches show great promise as x-ray sources for indirect-drive inertial confinement fusion (ICF). The double z-pinch hohlraum, for example, has produced capsule radiation drive symmetric to within 3%. This ICF concept will require that each of two 20-mm-diam arrays scale to x-ray powers ˜1 PW, to drive high-yield (>0.2 GJ) capsules to ignition. High-yield fusion will also require a temporally shaped radiation pulse to drive a low-entropy capsule implosion. Recently, improved understanding of high current (11-19 MA) single and nested wire-array dynamics has enabled significant progress towards these goals. As at lower currents, a single wire array (and both the outer and inner arrays of a nested system) shows a wire ablation phase, axial modulation of the ablation rate, a larger ablation rate for larger diameter wires, trailing mass and trailing current. These processes and others produce a broad mass profile that may impact the optimization of x-ray output for single and nested arrays. Our new insights into wire array physics have led to 20-mm-diam single and nested arrays with peak powers of 150-190 TW at implosion times of 55-90 ns, increased from 60-120 TW at 95-110 ns, improving power scaling. Radiation pulse shapes required for 3-shock isentropic compression of high-yield ICF capsules have also been demonstrated with nested wire arrays operating in current-transfer mode. In collaboration with: D.B. Sinars, R.A. Vesey, E.M. Waisman, W.A. Stygar, D.E. Bliss, S.V. Lebedev, J.P. Chittenden, P.V. Sasorov, R.W. Lemke, E.P. Yu, B.B. Afeyan, G.R. Bennett, M.G. Mazarakis, M.R. Lopez, M.E. Savage, J.L. Porter, T.A. Mehlhorn.

  4. Passive Acoustic Source Localization at a Low Sampling Rate Based on a Five-Element Cross Microphone Array

    Directory of Open Access Journals (Sweden)

    Yue Kan

    2015-06-01

    Full Text Available Accurate acoustic source localization at a low sampling rate (less than 10 kHz is still a challenging problem for small portable systems, especially for a multitasking micro-embedded system. A modification of the generalized cross-correlation (GCC method with the up-sampling (US theory is proposed and defined as the US-GCC method, which can improve the accuracy of the time delay of arrival (TDOA and source location at a low sampling rate. In this work, through the US operation, an input signal with a certain sampling rate can be converted into another signal with a higher frequency. Furthermore, the optimal interpolation factor for the US operation is derived according to localization computation time and the standard deviation (SD of target location estimations. On the one hand, simulation results show that absolute errors of the source locations based on the US-GCC method with an interpolation factor of 15 are approximately from 1/15- to 1/12-times those based on the GCC method, when the initial same sampling rates of both methods are 8 kHz. On the other hand, a simple and small portable passive acoustic source localization platform composed of a five-element cross microphone array has been designed and set up in this paper. The experiments on the established platform, which accurately locates a three-dimensional (3D near-field target at a low sampling rate demonstrate that the proposed method is workable.

  5. Children 2.O, a formative experience in attitudes and values for teachers to Web 2.0 and TIC

    Directory of Open Access Journals (Sweden)

    Fernando GONZÁLEZ ALONSO

    2011-12-01

    Full Text Available 0 0 1 129 715 Instituto Universitario de Ciencias de la Educación 5 1 843 14.0 Normal 0 21 false false false ES JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} Children 2.0 is a formative experience for teachers working with children, based on attitudes and values that encourage the use of the tools of Web 2.0 and ICT. Attitudes which worked relate to overcome fears, undertake the culture 2.0 and becoming a teacher presumer; know, incorporate, and interact on the Web 2.0; unlearn, updated, and switch to new methodologies of collaborative learning with learning and knowledge technology; protect and monitor as educators access by minors to the network; create and contribute by exercising in workshop 2.0, focusing on services and Web applications, social networks, educational video, Wikis, blogs, mashups, folksonomy, and whiteboard. This formative action took place in a Conference in April 2011, in the UPSA, with the participation of experts, and with the good assessment of the participants.

  6. Growth of carbon nanocone arrays on a metal catalyst: The effect of carbon flux ionization

    International Nuclear Information System (INIS)

    Levchenko, I.; Khachan, J.; Vladimirov, S. V.; Ostrikov, K.

    2008-01-01

    The growth of carbon nanocone arrays on metal catalyst particles by deposition from a low-temperature plasma is studied by multiscale Monte Carlo/surface diffusion numerical simulation. It is demonstrated that the variation in the degree of ionization of the carbon flux provides an effective control of the growth kinetics of the carbon nanocones, and leads to the formation of more uniform arrays of nanostructures. In the case of zero degree of ionization (neutral gas process), a width of the distribution of nanocone heights reaches 360 nm with the nanocone mean height of 150 nm. When the carbon flux of 75% ionization is used, the width of the distribution of nanocone heights decreases to 100 nm, i.e., by a factor of 3.6. A higher degree of ionization leads to a better uniformity of the metal catalyst saturation and the nanocone growth, thus contributing to the formation of more height-uniform arrays of carbon nanostructures.

  7. Precisely Assembled Nanofiber Arrays as a Platform to Engineer Aligned Cell Sheets for Biofabrication

    Directory of Open Access Journals (Sweden)

    Vince Beachley

    2014-08-01

    Full Text Available A hybrid cell sheet engineering approach was developed using ultra-thin nanofiber arrays to host the formation of composite nanofiber/cell sheets. It was found that confluent aligned cell sheets could grow on uniaxially-aligned and crisscrossed nanofiber arrays with extremely low fiber densities. The porosity of the nanofiber sheets was sufficient to allow aligned linear myotube formation from differentiated myoblasts on both sides of the nanofiber sheets, in spite of single-side cell seeding. The nanofiber content of the composite cell sheets is minimized to reduce the hindrance to cell migration, cell-cell contacts, mass transport, as well as the foreign body response or inflammatory response associated with the biomaterial. Even at extremely low densities, the nanofiber component significantly enhanced the stability and mechanical properties of the composite cell sheets. In addition, the aligned nanofiber arrays imparted excellent handling properties to the composite cell sheets, which allowed easy processing into more complex, thick 3D structures of higher hierarchy. Aligned nanofiber array-based composite cell sheet engineering combines several advantages of material-free cell sheet engineering and polymer scaffold-based cell sheet engineering; and it represents a new direction in aligned cell sheet engineering for a multitude of tissue engineering applications.

  8. SNP Arrays

    Directory of Open Access Journals (Sweden)

    Jari Louhelainen

    2016-10-01

    Full Text Available The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands that focus to include areas such as rare conditions, animal breeding and bioinformatics tools. Given the limited scope, the spectrum of papers is nothing short of remarkable and even from a technical point of view these papers will contribute to the field at a general level. Three of the papers published in this Special Issue focus on the use of various SNP array approaches in the analysis of three different cancer types. Two of the papers concentrate on two very different rare conditions, applying the SNP arrays slightly differently. Finally, two other papers evaluate the use of the SNP arrays in the context of genetic analysis of livestock. The findings reported in these papers help to close gaps in the current literature and also to give guidelines for future applications of SNP arrays.

  9. Khz-cp (crude polysaccharide extract obtained from the fusion of Ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis by increasing intracellular calcium levels and activating P38 and NADPH oxidase-dependent generation of reactive oxygen species in SNU-1 cells.

    Science.gov (United States)

    Kim, Tae Hwan; Kim, Ju Sung; Kim, Zoo Haye; Huang, Ren Bin; Chae, Young Lye; Wang, Ren Sheng

    2014-07-10

    Khz-cp is a crude polysaccharide extract that is obtained after nuclear fusion in Ganoderma lucidum and Polyporus umbellatus mycelia (Khz). It inhibits the growth of cancer cells. Khz-cp was extracted by solvent extraction. The anti-proliferative activity of Khz-cp was confirmed by using Annexin-V/PI-flow cytometry analysis. Intracellular calcium increase and measurement of intracellular reactive oxygen species (ROS) were performed by using flow cytometry and inverted microscope. SNU-1 cells were treated with p38, Bcl-2 and Nox family siRNA. siRNA transfected cells was employed to investigate the expression of apoptotic, growth and survival genes in SNU-1 cells. Western blot analysis was performed to confirm the expression of the genes. In the present study, Khz-cp induced apoptosis preferentially in transformed cells and had only minimal effects on non-transformed cells. Furthermore, Khz-cp was found to induce apoptosis by increasing the intracellular Ca2+ concentration ([Ca2+]i) and activating P38 to generate reactive oxygen species (ROS) via NADPH oxidase and the mitochondria. Khz-cp-induced apoptosis was caspase dependent and occurred via a mitochondrial pathway. ROS generation by NADPH oxidase was critical for Khz-cp-induced apoptosis, and although mitochondrial ROS production was also required, it appeared to occur secondary to ROS generation by NADPH oxidase. Activation of NADPH oxidase was shown by the translocation of the regulatory subunits p47phox and p67phox to the cell membrane and was necessary for ROS generation by Khz-cp. Khz-cp triggered a rapid and sustained increase in [Ca2+]i that activated P38. P38 was considered to play a key role in the activation of NADPH oxidase because inhibition of its expression or activity abrogated membrane translocation of the p47phox and p67phox subunits and ROS generation. In summary, these data indicate that Khz-cp preferentially induces apoptosis in cancer cells and that the signaling mechanisms involve an

  10. A superconducting quadrupole array for transport of multiple high current beams

    International Nuclear Information System (INIS)

    Faltens, A.; Shuman, D.

    1999-01-01

    We present a conceptual design of a superconducting quadrupole magnet array for the side-by-side transport of multiple high current particle beams in induction linear accelerators. The magnetic design uses a modified cosine 20 current distribution inside a square cell boundary. Each interior magnet's neighbors serve as the return flux paths and the poles are placed as close as possible to each other to facilitate this. No iron is present in the basic 2-D magnetic design; it will work at any current level without correction windings. Special 1/8th quadrupoles are used along the transverse periphery of the array to contain and channel flux back into the array, making every channel look as part of an infinite array. This design provides a fixed dimension array boundary equal to the quadrupole radius that can be used for arrays of any number of quadrupole channels, at any field level. More importantly, the design provides magnetic field separation between the array and the induction cores which may be surrounding it. Flux linkage between these two components can seriously affect the operation of both of them

  11. L-ASPARAGINASE FROM BACILLUS SP. RKS-20: PROCESS OPTIMIZATION AND APPLICATION IN THE INHIBITION OF ACRYLAMIDE FORMATION IN FRIED FOODS

    Directory of Open Access Journals (Sweden)

    Richi V. Mahajan

    2014-08-01

    Full Text Available Reports of presence of acrylamide in wide range of fried and baked foods, most notably potato chips and French fries, by Swedish researchers in 2002 has raised a worldwide concern. However, the enzyme Lasparaginase reduces the formation of acrylamide in fried foods by pre-amidohydrolase of L-asparagine present. In this context, we report the hyper production of L-asparaginase from Bacillus sp. RKS-20, by process optimization involving statistical modeling approach. A maximum of 15.10 IU/ml of L-asparaginase were obtained in 18h under statistically optimized conditions wherein KH2 PO4 (3.0 g/L, NaCl (1.0 g/L, L-asparagine (14.0 g/L and glucose (2.0 g/L were the influential factors. This was an approximately 10-fold increase as compared to the initial un-optimized activity of 1.50 IU/ml. The potential of this enzyme for the inhibition of acrylamide formation was confirmed when the potato slices treated with L-asparaginase (40 IU/mg of dry potatoes, showed reduction of 69.80% in acrylamide formation upon frying as compared to untreated potato slices. Hence, this enzyme is potential candidate for healthier production of food.

  12. Pro-social 50-kHz ultrasonic communication in rats: Post-weaning but not post-adolescent social isolation leads to social impairments – phenotypic rescue by re-socialization

    Directory of Open Access Journals (Sweden)

    Dominik eSeffer

    2015-05-01

    Full Text Available Rats are highly social animals and social play during adolescence has an important role for social development, hence post-weaning social isolation is widely used to study the adverse effects of juvenile social deprivation and to induce behavioral phenotypes relevant to neuropsychiatric disorders, like schizophrenia. Communication is an important component of the rat’s social behavior repertoire, with ultrasonic vocalizations (USV serving as situation-dependent affective signals. High-frequency 50-kHz USV occur in appetitive situations and induce approach behavior, supporting the notion that they serve as social contact calls; however, post-weaning isolation effects on the behavioral changes displayed by the receiver in response to USV have yet to be studied. We therefore investigated the impact of post-weaning isolation on socio-affective information processing as assessed by means of our established 50-kHz USV radial maze playback paradigm. We showed that post-weaning social isolation specifically affected the behavioral response to playback of pro-social 50-kHz but not alarm 22-kHz USV. While group-housed rats showed the expected preference, i.e. approach, towards 50-kHz USV, the response was even stronger in short-term isolated rats (i.e. 1 day, possibly due to a higher level of social motivation. In contrast, no approach was observed in long-term isolated rats (i.e. 4 weeks. Importantly, deficits in approach were reversed by peer-mediated re-socialization and could not be observed after post-adolescent social isolation, indicating a critical period for social development during adolescence. Together, these results highlight the importance of social experience for affiliative behavior, suggesting a critical involvement of play behavior on socio-affective information processing in rats.

  13. A novel method to design sparse linear arrays for ultrasonic phased array.

    Science.gov (United States)

    Yang, Ping; Chen, Bin; Shi, Ke-Ren

    2006-12-22

    In ultrasonic phased array testing, a sparse array can increase the resolution by enlarging the aperture without adding system complexity. Designing a sparse array involves choosing the best or a better configuration from a large number of candidate arrays. We firstly designed sparse arrays by using a genetic algorithm, but found that the arrays have poor performance and poor consistency. So, a method based on the Minimum Redundancy Linear Array was then adopted. Some elements are determined by the minimum-redundancy array firstly in order to ensure spatial resolution and then a genetic algorithm is used to optimize the remaining elements. Sparse arrays designed by this method have much better performance and consistency compared to the arrays designed only by a genetic algorithm. Both simulation and experiment confirm the effectiveness.

  14. The potential of TaqMan Array Cards for detection of multiple biological agents by real-time PCR.

    Directory of Open Access Journals (Sweden)

    Phillip A Rachwal

    Full Text Available The TaqMan Array Card architecture, normally used for gene expression studies, was evaluated for its potential to detect multiple bacterial agents by real-time PCR. Ten PCR assays targeting five biological agents (Bacillus anthracis, Burkholderia mallei, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis were incorporated onto Array Cards. A comparison of PCR performance of each PCR in Array Card and singleplex format was conducted using DNA extracted from pure bacterial cultures. When 100 fg of agent DNA was added to Array Card channels the following levels of agent detection (where at least one agent PCR replicate returned a positive result were observed: Y. pestis 100%, B. mallei & F. tularensis 93%; B. anthracis 71%; B. pseudomallei 43%. For B. mallei & pseudomallei detection the BPM2 PCR, which detects both species, outperformed PCR assays specific to each organism indicating identification of the respective species would not be reproducible at the 100 fg level. Near 100% levels of detection were observed when 100 fg of DNA was added to each PCR in singleplex format with singleplex PCRs also returning sporadic positives at the 10 fg per PCR level. Before evaluating the use of Array Cards for the testing of environmental and clinical sample types, with potential levels of background DNA and PCR inhibitors, users would therefore have to accept a 10-fold reduction in sensitivity of PCR assays on the Array Card format, in order to benefit for the capacity to test multiple samples for multiple agents. A two PCR per agent strategy would allow the testing of 7 samples for the presence of 11 biological agents or 3 samples for 23 biological agents per card (with negative control channels.

  15. Reducing mechanical cross-coupling in phased array transducers using stop band material as backing

    Science.gov (United States)

    Henneberg, J.; Gerlach, A.; Storck, H.; Cebulla, H.; Marburg, S.

    2018-06-01

    Phased array transducers are widely used for acoustic imaging and surround sensing applications. A major design challenge is the achievement of low mechanical cross-coupling between the single transducer elements. Cross-coupling induces a loss of imaging resolution. In this work, the mechanical cross-coupling between acoustic transducers is investigated for a generic model. The model contains a common backing with two bending elements bonded on top. The dimensions of the backing are small; thus, wave reflections on the backing edges have to be considered. This is different to other researches. The operating frequency in the generic model is set to a low kHz range. Low operating frequencies are typical for surround sensing applications. The influence of the backing on cross-coupling is investigated numerically. In order to reduce mechanical cross-coupling a stop band material is designed. It is shown numerically that a reduction in mechanical cross-coupling can be achieved by using stop band material as backing. The effect is validated with experimental testing.

  16. A Study of Array Direction HDPE Fiber Reinforced Mortar

    Science.gov (United States)

    Kamsuwan, Trithos

    2018-02-01

    This paper presents the effect of array direction HDPE fiber using as the reinforced material in cement mortar. The experimental data were created reference to the efficiency of using HDPE fiber reinforced on the tensile properties of cement mortar with different high drawn ratio of HDPE fibers. The fiber with the different drawn ratio 25x (d25 with E xx), and 35x (d35 with E xx) fiber volume fraction (0%, 1.0%, 1.5%) and fiber length 20 mm. were used to compare between random direction and array direction of HDPE fibers and the stress - strain displacement relationship behavior of HDPE short fiber reinforced cement mortar were investigated. It was found that the array direction with HDPE fibers show more improved in tensile strength and toughness when reinforced in cement mortar.

  17. A compact and continuously driven supersonic plasma and neutral source

    Energy Technology Data Exchange (ETDEWEB)

    Asai, T.; Itagaki, H.; Numasawa, H.; Terashima, Y.; Hirano, Y. [Department of Physics, College of Science and Technology, Nihon University, Tokyo 101-8308 (Japan); Hirose, A. [Plasma Physics Laboratory, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E2 (Canada)

    2010-10-15

    A compact and repetitively driven plasma source has been developed by utilizing a magnetized coaxial plasma gun (MCPG) for diagnostics requiring deep penetration of a large amount of neutral flux. The system consists of a MCPG 95mm in length with a DN16 ConFlat connection port and an insulated gate bipolar transistor (IGBT) inverter power unit. The power supply consists of an array of eight IGBT units and is able to switch the discharge on and off at up to 10 kV and 600 A with a maximum repetitive frequency of 10 kHz. Multiple short duration discharge pulses maximize acceleration efficiency of the plasmoid. In the case of a 10 kHz operating frequency, helium-plasmoids in the velocity range of 20 km/s can be achieved.

  18. A compact and continuously driven supersonic plasma and neutral source.

    Science.gov (United States)

    Asai, T; Itagaki, H; Numasawa, H; Terashima, Y; Hirano, Y; Hirose, A

    2010-10-01

    A compact and repetitively driven plasma source has been developed by utilizing a magnetized coaxial plasma gun (MCPG) for diagnostics requiring deep penetration of a large amount of neutral flux. The system consists of a MCPG 95mm in length with a DN16 ConFlat connection port and an insulated gate bipolar transistor (IGBT) inverter power unit. The power supply consists of an array of eight IGBT units and is able to switch the discharge on and off at up to 10 kV and 600 A with a maximum repetitive frequency of 10 kHz. Multiple short duration discharge pulses maximize acceleration efficiency of the plasmoid. In the case of a 10 kHz operating frequency, helium-plasmoids in the velocity range of 20 km/s can be achieved.

  19. Continuous single pulse resolved measurement of beam diameters at 200 kHz using optical transmission filters

    Science.gov (United States)

    Fruechtenicht, Johannes; Letsch, Andreas; Voss, Andreas; Abdou Ahmed, Marwan; Graf, Thomas

    2012-02-01

    We present a novel laser beam measurement setup which allows the determination of the beam diameter for each single pulse of a pulsed laser beam at repetition rates of up to 200 kHz. This is useful for online process-parameter control e.g. in micromachining or for laser source characterization. Basically, the developed instrument combines spatial transmission filters specially designed for instantaneous optical determination of the second order moments of the lateral intensity distribution of the light beam and photodiodes coupled to customized electronics. The acquisition is computer-based, enabling real-time operation for online monitoring or control. It also allows data storage for a later analysis and visualization of the measurement results. The single-pulse resolved beam diameter can be measured and recorded without any interruption for an unlimited number of pulses. It is only limited by the capacity of the data storage means. In our setup a standard PC and hard-disk provided 2 hours uninterrupted operation and recording of varying beam diameters at 200 kHz. This is about three orders of magnitude faster than other systems. To calibrate our device we performed experiments in cw and pulsed regimes and the obtained results were compared to those obtained with a commercial camera based system. Only minor deviations of the beam diameter values between the two instruments were observed, proving the reliability of our approach.

  20. A general technique for characterizing x-ray position sensitive arrays

    International Nuclear Information System (INIS)

    Dufresne, E.; Bruning, R.; Sutton, M.; Stephenson, G.B.

    1994-03-01

    We present a general statistical technique for characterizing x-ray sensitive linear diode arrays and CCD arrays. We apply this technique to characterize the response of a linear diode array, Princeton Instrument model X-PDA, and a virtual phase CCD array, TI 4849, to direct illumination by x-rays. We find that the response of the linear array is linearly proportional to the incident intensity and uniform over its length to within 2 %. Its quantum efficiency is 38 % for Cu K α x-rays. The resolution function is evaluated from the spatial autocorrelation function and falls to 10 % of its peak value after one pixel. On the other hand, the response of the CCD detecting system to direct x-ray exposure is non-linear. To properly quantify the scattered x-rays, one must correct for the non- linearity. The resolution is two pixels along the serial transfer direction. We characterize the noise of the CCD and propose a model that takes into account the non-linearity and the resolution function to estimate the quantum efficiency of the detector. The quantum efficiency is 20 %

  1. TiO2 nanocrystals decorated Z-schemed core-shell CdS-CdO nanorod arrays as high efficiency anodes for photoelectrochemical hydrogen generation.

    Science.gov (United States)

    Li, Chia-Hsun; Hsu, Chan-Wei; Lu, Shih-Yuan

    2018-07-01

    TiO 2 nanocrystals decorated core-shell CdS-CdO nanorod arrays, TiO 2 @CdO/CdS NR, were fabricated as high efficiency anodes for photoelctrochemical hydrogen generation. The novel sandwich heterostructure was constructed from first growth of CdS nanorod arrays on a fluorine doped tin oxide (FTO) substrate with a hydrothermal process, followed by in situ generation of CdO thin films of single digit nanometers from the CdS nanorod surfaces through thermal oxidation, and final decoration of TiO 2 nanocrystals of 10-20 nm via a successive ionic layer absorption and reaction process. The core-shell CdS-CdO heterostructure possesses a Z-scheme band structure to enhance interfacial charge transfer, facilitating effective charge separation to suppress electron-hole recombination within CdS for much improved current density generation. The final decoration of TiO 2 nanocrystals passivates surface defects and trap states of CdO, further suppressing surface charge recombination for even higher photovoltaic conversion efficiencies. The photoelectrochemical performances of the plain CdS nanorod array were significantly improved with the formation of the sandwich heterostructure, achieving a photo current density of 3.2 mA/cm 2 at 1.23 V (vs. RHE), a 141% improvement over the plain CdS nanorod array and a 32% improvement over the CdO/CdS nanorod array. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. A design concept for an MMIC (Monolithic Microwave Integrated Circuit) microstrip phased array

    Science.gov (United States)

    Lee, Richard Q.; Smetana, Jerry; Acosta, Roberto

    1987-01-01

    A conceptual design for a microstrip phased array with monolithic microwave integrated circuit (MMIC) amplitude and phase controls is described. The MMIC devices used are 20 GHz variable power amplifiers and variable phase shifters recently developed by NASA contractors for applications in future Ka proposed design, which concept is for a general NxN element array of rectangular lattice geometry. Subarray excitation is incorporated in the MMIC phased array design to reduce the complexity of the beam forming network and the number of MMIC components required.

  3. Removing Background Noise with Phased Array Signal Processing

    Science.gov (United States)

    Podboy, Gary; Stephens, David

    2015-01-01

    Preliminary results are presented from a test conducted to determine how well microphone phased array processing software could pull an acoustic signal out of background noise. The array consisted of 24 microphones in an aerodynamic fairing designed to be mounted in-flow. The processing was conducted using Functional Beam forming software developed by Optinav combined with cross spectral matrix subtraction. The test was conducted in the free-jet of the Nozzle Acoustic Test Rig at NASA GRC. The background noise was produced by the interaction of the free-jet flow with the solid surfaces in the flow. The acoustic signals were produced by acoustic drivers. The results show that the phased array processing was able to pull the acoustic signal out of the background noise provided the signal was no more than 20 dB below the background noise level measured using a conventional single microphone equipped with an aerodynamic forebody.

  4. Dendrite Array Disruption by Bubbles during Re-melting in a Microgravity Environment

    Science.gov (United States)

    Grugel, Richard N.

    2012-01-01

    As part of the Pore Formation and Mobility Investigation (PFMI), Succinonitrile Water alloys consisting of aligned dendritic arrays were re-melted prior to conducting directional solidification experiments in the microgravity environment aboard the International Space Station. Thermocapillary convection initiated by bubbles at the solid-liquid interface during controlled melt back of the alloy was observed to disrupt the initial dendritic alignment. Disruption ranged from detaching large arrays to the transport of small dendrite fragments at the interface. The role of bubble size and origin is discussed along with subsequent consequences upon reinitiating controlled solidification.

  5. Rectangular Full Packed Format for Cholesky's Algorithm: Factorization, Solution, and Inversion

    DEFF Research Database (Denmark)

    Gustavson, Fred G.; Wasniewski, Jerzy; Dongarra, Jack J

    2010-01-01

    of the storage space but provide high performance via the use of Level 3 BLAS. Standard packed format arrays fully utilize storage (array space) but provide low performance as there is no Level 3 packed BLAS. We combine the good features of packed and full storage using RFPF to obtain high performance via using...... Level 3 BLAS as RFPF is a standard full-format representation. Also, RFPF requires exactly the same minimal storage as packed the format. Each LAPACK full and/or packed triangular, symmetric, and Hermitian routine becomes a single new RFPF routine based on eight possible data layouts of RFPF. This new...... RFPF routine usually consists of two calls to the corresponding LAPACK full-format routine and two calls to Level 3 BLAS routines. This means no new software is required. As examples, we present LAPACK routines for Cholesky factorization, Cholesky solution, and Cholesky inverse computation in RFPF...

  6. Compression dynamics of quasi-spherical wire arrays with different linear mass profiles

    International Nuclear Information System (INIS)

    Mitrofanov, K. N.; Aleksandrov, V. V.; Gritsuk, A. N.; Grabovski, E. V.; Frolov, I. N.; Laukhin, Ya. N.; Oleinik, G. M.; Ol’khovskaya, O. G.

    2016-01-01

    Results of experimental studies of the implosion of quasi-spherical wire (or metalized fiber) arrays are presented. The goal of the experiments was to achieve synchronous three-dimensional compression of the plasma produced in different regions of a quasi-spherical array into its geometrical center. To search for optimal synchronization conditions, quasi-spherical arrays with different initial profiles of the linear mass were used. The following dependences of the linear mass on the poloidal angle were used: m_l(θ) ∝ sin"–"1θ and m_l(θ) ∝ sin"–"2θ. The compression dynamics of such arrays was compared with that of quasi-spherical arrays without linear mass profiling, m_l(θ) = const. To verify the experimental data, the spatiotemporal dynamics of plasma compression in quasi-spherical arrays was studied using various diagnostics. The experiments on three-dimensional implosion of quasi-spherical arrays made it possible to study how the frozen-in magnetic field of the discharge current penetrates into the array. By measuring the magnetic field in the plasma of a quasi-spherical array, information is obtained on the processes of plasma production and formation of plasma flows from the wire/fiber regions with and without an additionally deposited mass. It is found that penetration of the magnetic flux depends on the initial linear mass profile m_l(θ) of the quasi-spherical array. From space-resolved spectral measurements and frame imaging of plasma X-ray emission, information is obtained on the dimensions and shape of the X-ray source formed during the implosion of a quasi-spherical array. The intensity of this source is estimated and compared with that of the Z-pinch formed during the implosion of a cylindrical array.

  7. A tentative opinion of modeling plasma formation in metallic wire Z pinch

    International Nuclear Information System (INIS)

    Ding Ning

    2002-01-01

    Numerous experiments in both single wire and in wire arrays have attracted much attention. For the wire array Z-pinch implosions the plasma formation in the metallic wire Z pinches is a key question. By means of analyzing a number of single-wire and multi-wire experiments, two models to describe the behavior of a wire array Z-pinch in initial phase are suggested. In this phase each wire carries a rising current and behaves independently in a way similar to that found in single wire Z-pinch experiments in which a comparable current in one wire is employed. Based on one- or/and two-dimensional magnetohydrodynamics (MHD) theory, one model is used to simulate the electrical explosion stage of the metallic wire, another is used to simulate the wire-plasma formation stage

  8. Design and testing of 45 kV, 50 kHz pulse power supply for dielectric barrier discharges

    Science.gov (United States)

    Sharma, Surender Kumar; Shyam, Anurag

    2016-10-01

    The design, construction, and testing of high frequency, high voltage pulse power supply are reported. The purpose of the power supply is to generate dielectric barrier discharges for industrial applications. The power supply is compact and has the advantage of low cost, over current protection, and convenient control for voltage and frequency selection. The power supply can generate high voltage pulses of up to 45 kV at the repetitive frequency range of 1 kHz-50 kHz with 1.2 kW input power. The output current of the power supply is limited to 500 mA. The pulse rise time and fall time are less than 2 μs and the pulse width is 2 μs. The power supply is short circuit proof and can withstand variable plasma load conditions. The power supply mainly consists of a half bridge series resonant converter to charge an intermediate capacitor, which discharges through a step-up transformer at high frequency to generate high voltage pulses. Semiconductor switches and amorphous cores are used for power modulation at higher frequencies. The power supply is tested with quartz tube dielectric barrier discharge load and worked stably. The design details and the performance of the power supply on no load and dielectric barrier discharge load are presented.

  9. Linear-array systems for aerospace NDE

    International Nuclear Information System (INIS)

    Smith, Robert A.; Willsher, Stephen J.; Bending, Jamie M.

    1999-01-01

    Rapid large-area inspection of composite structures for impact damage and multi-layered aluminum skins for corrosion has been a recognized priority for several years in both military and civil aerospace applications. Approaches to this requirement have followed two clearly different routes: the development of novel large-area inspection systems, and the enhancement of current ultrasonic or eddy-current methods to reduce inspection times. Ultrasonic inspection is possible with standard flaw detection equipment but the addition of a linear ultrasonic array could reduce inspection times considerably. In order to investigate their potential, 9-element and 17-element linear ultrasonic arrays for composites, and 64-element arrays for aluminum skins, have been developed to DERA specifications for use with the ANDSCAN area scanning system. A 5 m 2 composite wing surface has been scanned with a scan resolution of approximately 3 mm in 6 hours. With subsequent software and hardware improvements all four composite wing surfaces (top/bottom, left/right) of a military fighter aircraft can potentially be inspected in less than a day. Array technology has been very widely used in the medical ultrasound field although rarely above 10 MHz, whereas lap-joint inspection requires a pulse center-frequency of 12 to 20 MHz in order to resolve the separate interfaces in the lap joint. A 128 mm-long multi-element array of 5 mmx2 mm ultrasonic elements for use with the ANDSCAN scanning software was produced to a DERA specification by an NDT manufacturer with experience in the medical imaging field. This paper analyses the performance of the transducers that have been produced and evaluates their use in scanning systems of different configurations

  10. Optimal Chunking of Large Multidimensional Arrays for Data Warehousing

    Energy Technology Data Exchange (ETDEWEB)

    Otoo, Ekow J; Otoo, Ekow J.; Rotem, Doron; Seshadri, Sridhar

    2008-02-15

    Very large multidimensional arrays are commonly used in data intensive scientific computations as well as on-line analytical processingapplications referred to as MOLAP. The storage organization of such arrays on disks is done by partitioning the large global array into fixed size sub-arrays called chunks or tiles that form the units of data transfer between disk and memory. Typical queries involve the retrieval of sub-arrays in a manner that access all chunks that overlap the query results. An important metric of the storage efficiency is the expected number of chunks retrieved over all such queries. The question that immediately arises is"what shapes of array chunks give the minimum expected number of chunks over a query workload?" The problem of optimal chunking was first introduced by Sarawagi and Stonebraker who gave an approximate solution. In this paper we develop exact mathematical models of the problem and provide exact solutions using steepest descent and geometric programming methods. Experimental results, using synthetic and real life workloads, show that our solutions are consistently within than 2.0percent of the true number of chunks retrieved for any number of dimensions. In contrast, the approximate solution of Sarawagi and Stonebraker can deviate considerably from the true result with increasing number of dimensions and also may lead to suboptimal chunk shapes.

  11. Calibration of the pressure sensitivity of microphones by a free-field method at frequencies up to 80 khz.

    Science.gov (United States)

    Zuckerwar, Allan J; Herring, G C; Elbing, Brian R

    2006-01-01

    A free-field (FF) substitution method for calibrating the pressure sensitivity of microphones at frequencies up to 80 kHz is demonstrated with both grazing and normal-incidence geometries. The substitution-based method, as opposed to a simultaneous method, avoids problems associated with the nonuniformity of the sound field and, as applied here, uses a 1/4-in. air-condenser pressure microphone as a known reference. Best results were obtained with a centrifugal fan, which is used as a random, broadband sound source. A broadband source minimizes reflection-related interferences that can plague FF measurements. Calibrations were performed on 1/4-in. FF air-condenser, electret, and microelectromechanical systems (MEMS) microphones in an anechoic chamber. The uncertainty of this FF method is estimated by comparing the pressure sensitivity of an air-condenser FF microphone, as derived from the FF measurement, with that of an electrostatic actuator calibration. The root-mean-square difference is found to be +/- 0.3 dB over the range 1-80 kHz, and the combined standard uncertainty of the FF method, including other significant contributions, is +/- 0.41 dB.

  12. Efficient oligonucleotide probe selection for pan-genomic tiling arrays

    Directory of Open Access Journals (Sweden)

    Zhang Wei

    2009-09-01

    Full Text Available Abstract Background Array comparative genomic hybridization is a fast and cost-effective method for detecting, genotyping, and comparing the genomic sequence of unknown bacterial isolates. This method, as with all microarray applications, requires adequate coverage of probes targeting the regions of interest. An unbiased tiling of probes across the entire length of the genome is the most flexible design approach. However, such a whole-genome tiling requires that the genome sequence is known in advance. For the accurate analysis of uncharacterized bacteria, an array must query a fully representative set of sequences from the species' pan-genome. Prior microarrays have included only a single strain per array or the conserved sequences of gene families. These arrays omit potentially important genes and sequence variants from the pan-genome. Results This paper presents a new probe selection algorithm (PanArray that can tile multiple whole genomes using a minimal number of probes. Unlike arrays built on clustered gene families, PanArray uses an unbiased, probe-centric approach that does not rely on annotations, gene clustering, or multi-alignments. Instead, probes are evenly tiled across all sequences of the pan-genome at a consistent level of coverage. To minimize the required number of probes, probes conserved across multiple strains in the pan-genome are selected first, and additional probes are used only where necessary to span polymorphic regions of the genome. The viability of the algorithm is demonstrated by array designs for seven different bacterial pan-genomes and, in particular, the design of a 385,000 probe array that fully tiles the genomes of 20 different Listeria monocytogenes strains with overlapping probes at greater than twofold coverage. Conclusion PanArray is an oligonucleotide probe selection algorithm for tiling multiple genome sequences using a minimal number of probes. It is capable of fully tiling all genomes of a species on

  13. Paper-based immune-affinity arrays for detection of multiple mycotoxins in cereals.

    Science.gov (United States)

    Li, Li; Chen, Hongpu; Lv, Xiaolan; Wang, Min; Jiang, Xizhi; Jiang, Yifei; Wang, Heye; Zhao, Yongfu; Xia, Liru

    2018-03-01

    Mycotoxins produced by different species of fungi may coexist in cereals and feedstuffs, and could be highly toxic for humans and animals. For quantification of multiple mycotoxins in cereals, we developed a paper-based mycotoxin immune-affinity array. First, paper-based microzone arrays were fabricated by photolithography. Then, monoclonal mycotoxin antibodies were added in a copolymerization reaction with a cross-linker to form an immune-affinity monolith on the paper-based microzone array. With use of a competitive immune-response format, paper-based mycotoxin immune-affinity arrays were successfully applied to detect mycotoxins in samples. The detection limits for deoxynivalenol, zearalenone, T-2 toxin, and HT-2 toxin were 62.7, 10.8, 0.36, and 0.23 μg·kg -1 , respectively, which meet relevant requirements for these compounds in food. The recovery rates were 81-86% for deoxynivalenol, 89-117% for zearalenone, 79-86% for T-2 toxin, and 78-83% for HT-2 toxin, and showed the paper-based immune-affinity arrays had good reproducibility. In summary, the paper-based mycotoxin immune-affinity array provides a sensitive, rapid, accurate, stable, and convenient platform for detection of multiple mycotoxins in agro-foods. Graphical abstract Paper-based immune-affinity monolithic array. DON deoxynivalenol, HT-2 HT-2 toxin, T-2 T-2 toxin, PEGDA polyethylene glycol diacrylate, ZEN zearalenone.

  14. Detector array for measurement of high-frequency fluctuations in visible and near-UV emission from tokamaks

    International Nuclear Information System (INIS)

    Hurwitz, P.D.; Hall, B.F.; Rowan, W.L.

    1992-01-01

    We developed an imaging detector to measure high-frequency fluctuations in visible and near-UV emission from tokamaks. The detector is intended for the study of plasma turbulence, mhd phenomena, and edge-localized modes. Particularly in the first two applications, it will complement existing techniques by providing higher spatial resolution as well as measurement capability in otherwise inaccessible regions of the plasma. The device consists of an optical system, a linear array of 32 photodiodes, and an amplifier for each photodiode. The amplifiers have a transimpedance gain of 10 5 --10 6 and the frequency response is flat to 100 kHz. Experience with this device has shown that optical imaging systems can be easily designed and tailored to a specific measurement because of the small size and close spacing of the individual light-sensitive elements. The device has been successfully tested on TEXT-U in measurements of H α fluctuations

  15. BOREAS TE-20 Soils Data Over the NSA-MSA and Tower Sites in Raster Format

    Science.gov (United States)

    Hall, Forrest G. (Editor); Veldhuis, Hugo; Knapp, David; Veldhuis, Hugo

    2000-01-01

    The BOREAS TE-20 team collected several data sets for use in developing and testing models of forest ecosystem dynamics. This data set was gridded from vector layers of soil maps that were received from Dr. Hugo Veldhuis, who did the original mapping in the field during 1994. The vector layers were gridded into raster files that cover the NSA-MSA and tower sites. The data are stored in binary, image format files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Center (DAAC).

  16. QSpike Tools: a Generic Framework for Parallel Batch Preprocessing of Extracellular Neuronal Signals Recorded by Substrate Microelectrode Arrays

    Directory of Open Access Journals (Sweden)

    Mufti eMahmud

    2014-03-01

    Full Text Available Micro-Electrode Arrays (MEAs have emerged as a mature technique to investigate brain (dysfunctions in vivo and in in vitro animal models. Often referred to as smart Petri dishes, MEAs has demonstrated a great potential particularly for medium-throughput studies in vitro, both in academic and pharmaceutical industrial contexts. Enabling rapid comparison of ionic/pharmacological/genetic manipulations with control conditions, MEAs are often employed to screen compounds by monitoring non-invasively the spontaneous and evoked neuronal electrical activity in longitudinal studies, with relatively inexpensive equipment. However, in order to acquire sufficient statistical significance, recordings last up to tens of minutes and generate large amount of raw data (e.g., 60 channels/MEA, 16 bits A/D conversion, 20kHz sampling rate: ~8GB/MEA,h uncompressed. Thus, when the experimental conditions to be tested are numerous, the availability of fast, standardized, and automated signal preprocessing becomes pivotal for any subsequent analysis and data archiving. To this aim, we developed an in-house cloud-computing system, named QSpike Tools, where CPU-intensive operations, required for preprocessing of each recorded channel (e.g., filtering, multi-unit activity detection, spike-sorting, etc., are decomposed and batch-queued to a multi-core architecture or to computer cluster. With the commercial availability of new and inexpensive high-density MEAs, we believe that disseminating QSpike Tools might facilitate its wide adoption and customization, and possibly inspire the creation of community-supported cloud-computing facilities for MEAs users.

  17. QSpike tools: a generic framework for parallel batch preprocessing of extracellular neuronal signals recorded by substrate microelectrode arrays.

    Science.gov (United States)

    Mahmud, Mufti; Pulizzi, Rocco; Vasilaki, Eleni; Giugliano, Michele

    2014-01-01

    Micro-Electrode Arrays (MEAs) have emerged as a mature technique to investigate brain (dys)functions in vivo and in in vitro animal models. Often referred to as "smart" Petri dishes, MEAs have demonstrated a great potential particularly for medium-throughput studies in vitro, both in academic and pharmaceutical industrial contexts. Enabling rapid comparison of ionic/pharmacological/genetic manipulations with control conditions, MEAs are employed to screen compounds by monitoring non-invasively the spontaneous and evoked neuronal electrical activity in longitudinal studies, with relatively inexpensive equipment. However, in order to acquire sufficient statistical significance, recordings last up to tens of minutes and generate large amount of raw data (e.g., 60 channels/MEA, 16 bits A/D conversion, 20 kHz sampling rate: approximately 8 GB/MEA,h uncompressed). Thus, when the experimental conditions to be tested are numerous, the availability of fast, standardized, and automated signal preprocessing becomes pivotal for any subsequent analysis and data archiving. To this aim, we developed an in-house cloud-computing system, named QSpike Tools, where CPU-intensive operations, required for preprocessing of each recorded channel (e.g., filtering, multi-unit activity detection, spike-sorting, etc.), are decomposed and batch-queued to a multi-core architecture or to a computers cluster. With the commercial availability of new and inexpensive high-density MEAs, we believe that disseminating QSpike Tools might facilitate its wide adoption and customization, and inspire the creation of community-supported cloud-computing facilities for MEAs users.

  18. A Novel Self-aligned and Maskless Process for Formation of Highly Uniform Arrays of Nanoholes and Nanopillars

    Directory of Open Access Journals (Sweden)

    Wu Wei

    2008-01-01

    Full Text Available AbstractFabrication of a large area of periodic structures with deep sub-wavelength features is required in many applications such as solar cells, photonic crystals, and artificial kidneys. We present a low-cost and high-throughput process for realization of 2D arrays of deep sub-wavelength features using a self-assembled monolayer of hexagonally close packed (HCP silica and polystyrene microspheres. This method utilizes the microspheres as super-lenses to fabricate nanohole and pillar arrays over large areas on conventional positive and negative photoresist, and with a high aspect ratio. The period and diameter of the holes and pillars formed with this technique can be controlled precisely and independently. We demonstrate that the method can produce HCP arrays of hole of sub-250 nm size using a conventional photolithography system with a broadband UV source centered at 400 nm. We also present our 3D FDTD modeling, which shows a good agreement with the experimental results.

  19. Colorimetric sensor array for determination and identification of toxic industrial chemicals.

    Science.gov (United States)

    Feng, Liang; Musto, Christopher J; Kemling, Jonathan W; Lim, Sung H; Zhong, Wenxuan; Suslick, Kenneth S

    2010-11-15

    A low-cost yet highly sensitive colorimetric sensor array for the detection and identification of toxic industrial chemicals (TICs) has been developed. The sensor consists of a disposable array of cross-responsive nanoporous pigments whose colors are changed by diverse chemical interactions with analytes. Clear differentiation among 20 different TICs has been easily achieved at both their IDLH (immediately dangerous to life or health) concentration within 2 min of exposure and PEL (permissible exposure limit) concentration within 5 min of exposure with no errors or misclassifications. Detection limits are generally well below the PEL (in most cases below 5% of PEL) and are typically in the low ppb range. The colorimetric sensor array is not responsive to changes in humidity or temperature over a substantial range. The printed arrays show excellent batch to batch reproducibility and long shelf life (greater than 3 months).

  20. The oxidized porous silicon field emission array

    International Nuclear Information System (INIS)

    Smith, D.D.; Demroff, H.P.; Elliott, T.S.; Kasprowicz, T.B.; Lee, B.; Mazumdar, T.K.; McIntyre, P.M.; Pang, Y.; Trost, H.J.

    1993-01-01

    The goal of developing a highly efficient microwave power source has led the authors to investigate new methods of electron field emission. One method presently under consideration involves the use of oxidized porous silicon thin films. The authors have used this technology to fabricate the first working field emission arrays from this substance. This approach reduces the diameter of an individual emitter to the nanometer scale. Tests of the first samples are encouraging, with extracted electron currents to nearly 1 mA resulting from less than 20 V of pulsed DC gate voltage. Modulated emission at 5 MHz was also observed. Developments of a full-scale emission array capable of delivering an electron beam at 18 GHz of minimum density 100 A/cm 2 is in progress

  1. Behavioral avoidance threshold level of a harbor porpoise (Phocoena phocoena) for a continuous 50 kHz pure tone (L)

    NARCIS (Netherlands)

    Kastelein, R.A.; Verboom, W.C.; Jennings, N.; Haan, D. de

    2008-01-01

    The use of ultrasonic sounds in alarms for gillnets may be advantageous, but the deterring effects of ultrasound on porpoises are not well understood. Therefore a harbor porpoise in a large floating pen was subjected to a continuous 50 kHz pure tone with a source level of 122 +/- 3dB (re 1uPa, rms).

  2. Behavioral avoidance threshold level of a harbor porpoise (Phocoena phocoena) for a continuous 50 kHz pure tone (L)

    NARCIS (Netherlands)

    Kastelein, R.A.; Verboom, W.C.; Jennings, N.; Haan, de D.

    2008-01-01

    The use of ultrasonic sounds in alarms for gillnets may be advantageous, but the deterring effects of ultrasound on porpoises are not well understood. Therefore a harbor porpoise in a large floating pen was subjected to a continuous 50 kHz pure tone with a source level of 122±3 dB (re 1 ¿Pa, rms).

  3. Developing infrared array controller with software real time operating system

    Science.gov (United States)

    Sako, Shigeyuki; Miyata, Takashi; Nakamura, Tomohiko; Motohara, Kentaro; Uchimoto, Yuka Katsuno; Onaka, Takashi; Kataza, Hirokazu

    2008-07-01

    Real-time capabilities are required for a controller of a large format array to reduce a dead-time attributed by readout and data transfer. The real-time processing has been achieved by dedicated processors including DSP, CPLD, and FPGA devices. However, the dedicated processors have problems with memory resources, inflexibility, and high cost. Meanwhile, a recent PC has sufficient resources of CPUs and memories to control the infrared array and to process a large amount of frame data in real-time. In this study, we have developed an infrared array controller with a software real-time operating system (RTOS) instead of the dedicated processors. A Linux PC equipped with a RTAI extension and a dual-core CPU is used as a main computer, and one of the CPU cores is allocated to the real-time processing. A digital I/O board with DMA functions is used for an I/O interface. The signal-processing cores are integrated in the OS kernel as a real-time driver module, which is composed of two virtual devices of the clock processor and the frame processor tasks. The array controller with the RTOS realizes complicated operations easily, flexibly, and at a low cost.

  4. Biophotofuel cell anode containing self-organized titanium dioxide nanotube array

    Energy Technology Data Exchange (ETDEWEB)

    Gan, Yong X., E-mail: yong.gan@utoledo.edu [Mechanical, Industrial and Manufacturing Engineering, College of Engineering, University of Toledo, 2801 W Bancroft Street, Toledo, OH 43606 (United States); Gan, Bo J. [Ottawa Hills High School, 2532 Evergreen Road, Toledo, OH 43606 (United States); Su Lusheng [Mechanical, Industrial and Manufacturing Engineering, College of Engineering, University of Toledo, 2801 W Bancroft Street, Toledo, OH 43606 (United States)

    2011-09-15

    Graphical abstract: Highlights: {center_dot} A photoactive anode containing highly ordered TiO{sub 2} nanotube array was made and the formation mechanism of self-organized TiO{sub 2} nanotube array on Ti was revealed. {center_dot} Effect of electrolyte concentration and voltage on the size distribution of the nanotubes was investigated. {center_dot} Self-organized TiO{sub 2} nanotube array anode possesses good photo-catalytic behavior of biomass decomposition under ultraviolet (UV) radiation. {center_dot} The fuel cell generates electricity and hydrogen via photoelectrochemical decomposition of ethanol, apple vinegar, sugar and tissue paper. - Abstract: We made a biophotofuel cell consisting of a titanium dioxide nanotube array photosensitive anode for biomass decomposition, and a low-hydrogen overpotential metal, Pt, as the cathode for hydrogen production. The titanium dioxide nanotubes (TiO{sub 2} NTs) were prepared via electrochemical oxidation of pure Ti in NaF solutions. Scanning electron microscopy was used to analyze the morphology of the nanotubes. The average diameter, wall thickness and length of the as-prepared TiO{sub 2} NTs were 88 {+-} 16 nm, 10 {+-} 2 nm and 491 {+-} 56 nm, respectively. Such dimensions are affected by the NaF concentration and the applied voltage during processing. Higher NaF concentrations result in the formation of longer and thicker nanotubes. The higher the voltage is, the thicker the nanotubes. The photosensitive anode made from the highly ordered TiO{sub 2} NTs has good photo-catalytic property, as can be seen from the test results of ethanol, apple vinegar, sugar and tissue paper decomposition under ultraviolet (UV) radiation. It is concluded that the biophotofuel cell with the TiO{sub 2} nanotube photoanode and a Pt cathode can generate electricity, hydrogen and clean water depending on the pH value and the oxygen presence in the solutions.

  5. AN OPPORTUNISTIC SEARCH FOR EXTRATERRESTRIAL INTELLIGENCE (SETI) WITH THE MURCHISON WIDEFIELD ARRAY

    Energy Technology Data Exchange (ETDEWEB)

    Tingay, S. J.; Tremblay, C.; Walsh, A.; Urquhart, R. [International Centre for Radio Astronomy Research (ICRAR), Curtin University, Bentley, WA 6102 (Australia)

    2016-08-20

    A spectral line image cube generated from 115 minutes of MWA data that covers a field of view of 400 sq, deg. around the Galactic Center is used to perform the first Search for ExtraTerrestrial Intelligence (SETI) with the Murchison Widefield Array (MWA). Our work constitutes the first modern SETI experiment at low radio frequencies, here between 103 and 133 MHz, paving the way for large-scale searches with the MWA and, in the future, the low-frequency Square Kilometre Array. Limits of a few hundred mJy beam{sup −1} for narrowband emission (10 kHz) are derived from our data, across our 400 sq. deg. field of view. Within this field, 45 exoplanets in 38 planetary systems are known. We extract spectra at the locations of these systems from our image cube to place limits on the presence of narrow line emission from these systems. We then derive minimum isotropic transmitter powers for these exoplanets; a small handful of the closest objects (10 s of pc) yield our best limits of order 10{sup 14} W (Equivalent Isotropic Radiated Power). These limits lie above the highest power directional transmitters near these frequencies currently operational on Earth. A SETI experiment with the MWA covering the full accessible sky and its full frequency range would require approximately one month of observing time. The MWA frequency range, its southern hemisphere location on an extraordinarily radio quiet site, its very large field of view, and its high sensitivity make it a unique facility for SETI.

  6. Seeded perturbations in wire array Z-Pinches

    International Nuclear Information System (INIS)

    Robinson, Allen Conrad; Fedin, Dmitry; Kantsyrev, Victor Leonidovich; Wunsch, Scott Edward; Oliver, Bryan Velten; Lebedev, Sergey V.; Coverdale, Christine Anne; Ouart, Nicholas D.; LePell, Paul David; Safronova, Alla S.; Shrestha, I.; McKenney, John Lee; Ampleford, David J.; Rapley, J.; Bott, S.C.; Palmer, J.B.A.; Sotnikov, Vladimir Isaakovich; Bland, Simon Nicholas; Ivanov, Vladimir V.; Chittenden, Jeremy Paul; Jones, B.; Garasi, Christopher Joseph; Hall, Gareth Neville; Yilmaz, M. Faith; Mehlhorn, Thomas Alan; Deeney, Christopher; Pokala, S.; Nalajala, V.

    2005-01-01

    Controlled seeding of perturbations is employed to study the evolution of wire array z-pinch implosion instabilities which strongly impact x-ray production when the 3D plasma stagnates on axis. Wires modulated in radius exhibit locally enhanced magnetic field and imploding bubble formation at discontinuities in wire radius due to the perturbed current path. Wires coated with localized spectroscopic dopants are used to track turbulent material flow. Experiments and MHD modeling offer insight into the behavior of z-pinch instabilities.

  7. Coupling in reflector arrays

    DEFF Research Database (Denmark)

    Appel-Hansen, Jørgen

    1968-01-01

    In order to reduce the space occupied by a reflector array, it is desirable to arrange the array antennas as close to each other as possible; however, in this case coupling between the array antennas will reduce the reflecting properties of the reflector array. The purpose of the present communic......In order to reduce the space occupied by a reflector array, it is desirable to arrange the array antennas as close to each other as possible; however, in this case coupling between the array antennas will reduce the reflecting properties of the reflector array. The purpose of the present...

  8. Surface-conduction electron-emitter characteristics and fabrication based on vertically aligned carbon nanotube arrays

    Energy Technology Data Exchange (ETDEWEB)

    Shih, Yi-Ting [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Li, Kuan-Wei [Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Honda, Shin-ichi [Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2280 (Japan); Lin, Pao-Hung; Huang, Ying-Sheng [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Lee, Kuei-Yi, E-mail: kylee@mail.ntust.edu.tw [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, No. 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China)

    2017-06-01

    Graphical abstract: The pattern design provides a new structure of surface-conduction electron-emitter display (SED). Delta-star shaped vertically aligned CNT (VACNT) arrays with 20o tips can simultaneously provide three emitters to bombard the sides of equilateral triangles pattern of VACNT, which produces numerous secondary electrons and enhance the SED efficiency. - Highlights: • The carbon nanotube (CNT) has replaced palladium oxide (PdO) as the electrode material for surface-conduction electron-emitter (SCE) applications. • The vertically aligned CNT (VACNT) arrays with 20° tips of the delta-star arrangement are used as cathodes that easily emit electrons. The cathode pattern simultaneously provides three emitters to bombard the sides of equilateral triangles pattern of VACNT. • The VACNT arrays were covered with magnesium oxide (MgO) nanostructures to promote the surface-conduction electron-emitter display (SED) efficiency (η). • The η was stably maintained in the 75–85% range. The proposed design provides a facile new method for developing SED applications. - Abstract: The carbon nanotube (CNT) has replaced palladium oxide (PdO) as the electrode material for surface-conduction electron-emitter (SCE) applications. Vertically aligned CNT arrays with a delta-star arrangement were patterned and synthesized onto a quartz substrate using photolithography and thermal chemical vapor deposition. Delta-star shaped VACNT arrays with 20° tips are used as cathodes that easily emit electrons because of their high electrical field gradient. In order to improve the field emission and secondary electrons (SEs) in SCE applications, magnesium oxide (MgO) nanostructures were coated onto the VACNT arrays to promote the surface-conduction electron-emitter display (SED) efficiency (η). According to the definition of η in SCE applications, in this study, the η was stably maintained in the 75–85% range. The proposed design provides a facile new method for

  9. The radio-X-ray relation as a star formation indicator: results from the Very Large Array-Extended Chandra Deep Field-South

    Science.gov (United States)

    Vattakunnel, S.; Tozzi, P.; Matteucci, F.; Padovani, P.; Miller, N.; Bonzini, M.; Mainieri, V.; Paolillo, M.; Vincoletto, L.; Brandt, W. N.; Luo, B.; Kellermann, K. I.; Xue, Y. Q.

    2012-03-01

    In order to trace the instantaneous star formation rate (SFR) at high redshift, and thus help in understanding the relation between the different emission mechanisms related to star formation, we combine the recent 4-Ms Chandra X-ray data and the deep Very Large Array radio data in the Extended Chandra Deep Field-South region. We find 268 sources detected both in the X-ray and radio bands. The availability of redshifts for ˜95 per cent of the sources in our sample allows us to derive reliable luminosity estimates and the intrinsic properties from X-ray analysis for the majority of the objects. With the aim of selecting sources powered by star formation in both bands, we adopt classification criteria based on X-ray and radio data, exploiting the X-ray spectral features and time variability, taking advantage of observations scattered across more than 10 years. We identify 43 objects consistent with being powered by star formation. We also add another 111 and 70 star-forming candidates detected only in the radio and X-ray bands, respectively. We find a clear linear correlation between radio and X-ray luminosity in star-forming galaxies over three orders of magnitude and up to z˜ 1.5. We also measure a significant scatter of the order of 0.4 dex, higher than that observed at low redshift, implying an intrinsic scatter component. The correlation is consistent with that measured locally, and no evolution with redshift is observed. Using a locally calibrated relation between the SFR and the radio luminosity, we investigate the LX(2-10 keV)-SFR relation at high redshift. The comparison of the SFR measured in our sample with some theoretical models for the Milky Way and M31, two typical spiral galaxies, indicates that, with current data, we can trace typical spirals only at z≤ 0.2, and strong starburst galaxies with SFRs as high as ˜100 M⊙ yr-1, up to z˜ 1.5.

  10. Nanodiamond arrays on glass for quantification and fluorescence characterisation.

    Science.gov (United States)

    Heffernan, Ashleigh H; Greentree, Andrew D; Gibson, Brant C

    2017-08-23

    Quantifying the variation in emission properties of fluorescent nanodiamonds is important for developing their wide-ranging applicability. Directed self-assembly techniques show promise for positioning nanodiamonds precisely enabling such quantification. Here we show an approach for depositing nanodiamonds in pre-determined arrays which are used to gather statistical information about fluorescent lifetimes. The arrays were created via a layer of photoresist patterned with grids of apertures using electron beam lithography and then drop-cast with nanodiamonds. Electron microscopy revealed a 90% average deposition yield across 3,376 populated array sites, with an average of 20 nanodiamonds per site. Confocal microscopy, optimised for nitrogen vacancy fluorescence collection, revealed a broad distribution of fluorescent lifetimes in agreement with literature. This method for statistically quantifying fluorescent nanoparticles provides a step towards fabrication of hybrid photonic devices for applications from quantum cryptography to sensing.

  11. Ge quantum dot arrays grown by ultrahigh vacuum molecular-beam epitaxy on the Si(001) surface: nucleation, morphology, and CMOS compatibility.

    Science.gov (United States)

    Yuryev, Vladimir A; Arapkina, Larisa V

    2011-09-05

    Issues of morphology, nucleation, and growth of Ge cluster arrays deposited by ultrahigh vacuum molecular beam epitaxy on the Si(001) surface are considered. Difference in nucleation of quantum dots during Ge deposition at low (≲600°C) and high (≳600°C) temperatures is studied by high resolution scanning tunneling microscopy. The atomic models of growth of both species of Ge huts--pyramids and wedges-- are proposed. The growth cycle of Ge QD arrays at low temperatures is explored. A problem of lowering of the array formation temperature is discussed with the focus on CMOS compatibility of the entire process; a special attention is paid upon approaches to reduction of treatment temperature during the Si(001) surface pre-growth cleaning, which is at once a key and the highest-temperature phase of the Ge/Si(001) quantum dot dense array formation process. The temperature of the Si clean surface preparation, the final high-temperature step of which is, as a rule, carried out directly in the MBE chamber just before the structure deposition, determines the compatibility of formation process of Ge-QD-array based devices with the CMOS manufacturing cycle. Silicon surface hydrogenation at the final stage of its wet chemical etching during the preliminary cleaning is proposed as a possible way of efficient reduction of the Si wafer pre-growth annealing temperature.

  12. Ge quantum dot arrays grown by ultrahigh vacuum molecular-beam epitaxy on the Si(001 surface: nucleation, morphology, and CMOS compatibility

    Directory of Open Access Journals (Sweden)

    Yuryev Vladimir

    2011-01-01

    Full Text Available Abstract Issues of morphology, nucleation, and growth of Ge cluster arrays deposited by ultrahigh vacuum molecular beam epitaxy on the Si(001 surface are considered. Difference in nucleation of quantum dots during Ge deposition at low (≲600°C and high (≳600°C temperatures is studied by high resolution scanning tunneling microscopy. The atomic models of growth of both species of Ge huts--pyramids and wedges-- are proposed. The growth cycle of Ge QD arrays at low temperatures is explored. A problem of lowering of the array formation temperature is discussed with the focus on CMOS compatibility of the entire process; a special attention is paid upon approaches to reduction of treatment temperature during the Si(001 surface pre-growth cleaning, which is at once a key and the highest-temperature phase of the Ge/Si(001 quantum dot dense array formation process. The temperature of the Si clean surface preparation, the final high-temperature step of which is, as a rule, carried out directly in the MBE chamber just before the structure deposition, determines the compatibility of formation process of Ge-QD-array based devices with the CMOS manufacturing cycle. Silicon surface hydrogenation at the final stage of its wet chemical etching during the preliminary cleaning is proposed as a possible way of efficient reduction of the Si wafer pre-growth annealing temperature.

  13. Inhibition of Steptococcus mutans biofilm formation by extracts of Tenacibaculum sp. 20J, a bacterium with wide-spectrum quorum quenching activity

    OpenAIRE

    Muras, Andrea; Mayer, Celia; Romero, Manuel; Camino, Tamara; Ferrer, Maria D.; Mira, Alex; Otero, Ana

    2018-01-01

    ABSTRACT Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhibitory activity was tested with the biosensors Vibrio harveyi BB170 and JMH597. S. mutans AT...

  14. SQUID multiplexing using baseband feedback for space application of transition-edge sensor microcalorimeters

    Energy Technology Data Exchange (ETDEWEB)

    Takei, Y; Yamasaki, N Y; Hirakoso, W; Kimura, S; Mitsuda, K, E-mail: takei@astro.isas.jaxa.j [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 3-1-1 Yoshinodai, Sagamihara, 229-8510 (Japan)

    2009-11-15

    A microcalorimeter array based on a transition-edge sensor (TES) thermometer is a promising imaging spectrometer for use in future x-ray astronomy missions. A TES microcalorimeter achieves {approx}<5 eV energy resolution and an array of >100 pixels also provides a moderate imaging capability. For a large format array, signal multiplexing at the low temperature stage is mandatory in order to reduce heat loads from cold stage preamplifiers and through wirings. We are developing frequency division multiplexing (FDM). In FDM, each TES is ac-biased with a different carrier frequency. Signals from several pixels are summed and then read out by one dc SQUID (superconducting quantum interference device). The maximum number of multiplexed pixels is limited by the bandwidth of a SQUID in a flux-locked loop. Assuming 1 m cable length between the room temperature and the cold stage, the bandwidth is only <1 MHz with a standard flux-locked loop, due to the delay and phase shift of wirings. We report our development of baseband feedback, a new feedback scheme that overcomes the bandwidth limitation. In baseband feedback, the signal ({approx}<10 kHz) from the TES is sent back to the SQUID after the phase of carrier frequency ({approx}1 MHz) has been adjusted. We demonstrated open-loop gain of 8 for 10 kHz signal at 5 MHz carrier frequency, which indicates the possibility of {approx}40-pixel multiplexing of the TES signal.

  15. Ordered alternating binary polymer nanodroplet array by sequential spin dewetting.

    Science.gov (United States)

    Bhandaru, Nandini; Das, Anuja; Salunke, Namrata; Mukherjee, Rabibrata

    2014-12-10

    We report a facile technique for fabricating an ordered array of nearly equal-sized mesoscale polymer droplets of two constituent polymers (polystyrene, PS and poly(methyl methacrylate), PMMA) arranged in an alternating manner on a topographically patterned substrate. The self-organized array of binary polymers is realized by sequential spin dewetting. First, a dilute solution of PMMA is spin-dewetted on a patterned substrate, resulting in an array of isolated PMMA droplets arranged along the substrate grooves due to self-organization during spin coating itself. The sample is then silanized with octadecyltrichlorosilane (OTS), and subsequently, a dilute solution of PS is spin-coated on to it, which also undergoes spin dewetting. The spin-dewetted PS drops having a size nearly equal to the pre-existing PMMA droplets position themselves between two adjacent PMMA drops under appropriate conditions, forming an alternating binary polymer droplet array. The alternating array formation takes place for a narrow range of solution concentration for both the polymers and depends on the geometry of the substrate. The size of the droplets depends on the extent of confinement, and droplets as small as 100 nm can be obtained by this method, on a suitable template. The findings open up the possibility of creating novel surfaces having ordered multimaterial domains with a potential multifunctional capability.

  16. Fan array wind tunnel: a multifunctional, complex environmental flow manipulator

    Science.gov (United States)

    Dougherty, Christopher; Veismann, Marcel; Gharib, Morteza

    2017-11-01

    The recent emergence of small unmanned aerial vehicles (UAVs) has reshaped the aerospace testing environment. Traditional closed-loop wind tunnels are not particularly suited nor easily retrofit to take advantage of these coordinated, controls-based rotorcraft. As such, a highly configurable, novel wind tunnel aimed at addressing the unmet technical challenges associated with single or formation flight performance of autonomous drone systems is presented. The open-loop fan array wind tunnel features 1296 individually controllable DC fans arranged in a 2.88m x 2.88m array. The fan array can operate with and without a tunnel enclosure and is able to rotate between horizontal and vertical testing configurations. In addition to standard variable speed uniform flow, the fan array can generate both unsteady and shear flows. Through the aid of smaller side fan array units, vortex flows are also possible. Conceptual design, fabrication, and validation of the tunnel performance will be presented, including theoretical and computational predictions of flow speed and turbulence intensity. Validation of these parameters is accomplished through standard pitot-static and hot-wire techniques. Particle image velocimetry (PIV) of various complex flows will also be shown. This material is based upon work supported by the Center for Autonomous Systems and Technologies (CAST) at the Graduate Aerospace Laboratories of the California Institute of Technology (GALCIT).

  17. Directional antenna array (DAA) for communications, control, and data link protection

    Science.gov (United States)

    Molchanov, Pavlo A.; Contarino, Vincent M.

    2013-06-01

    A next generation of Smart antennas with point-to-point communication and jam, spoof protection capability by verification of spatial position is offered. A directional antenna array (DAA) with narrow irradiation beam provides counter terrorism protection for communications, data link, control and GPS. Communications are "invisible" to guided missiles because of 20 dB smaller irradiation outside the beam and spatial separation. This solution can be implemented with current technology. Directional antennas have higher gain and can be multi-frequency or have wide frequency band in contrast to phase antenna arrays. This multi-directional antenna array provides a multi-functional communication network and simultaneously can be used for command control, data link and GPS.

  18. A Next Generation Light Source Facility at LBNL

    International Nuclear Information System (INIS)

    Corlett, J.N.; Austin, B.; Baptiste, K.M.; Byrd, J.M.; Denes, P.; Donahue, R.; Doolittle, L.; Falcone, R.W.; Filippetto, D.; Fournier, S.; Li, D.; Padmore, H.A.; Papadopoulos, C.; Pappas, C.; Penn, G.; Placidi, M.; Prestemon, S.; Prosnitz, D.; Qiang, J.; Ratti, A.; Reinsch, M.; Sannibale, F.; Schlueter, R.; Schoenlein, R.W.; Staples, J.W.; Vecchione, T.; Venturini, M.; Wells, R.; Wilcox, R.; Wurtele, J.; Charman, A.; Kur, E.; Zholents, A.A.

    2011-01-01

    The Next Generation Light Source (NGLS) is a design concept, under development at LBNL, for a multibeamline soft x-ray FEL array powered by a ∼2 GeV superconducting linear accelerator, operating with a 1 MHz bunch repetition rate. The CW superconducting linear accelerator is supplied by a high-brightness, high-repetition-rate photocathode electron gun. Electron bunches are distributed from the linac to the array of independently configurable FEL beamlines with nominal bunch rates up to 100 kHz in each FEL, and with even pulse spacing. Individual FELs may be configured for EEHG, HGHG, SASE, or oscillator mode of operation, and will produce high peak and average brightness x-rays with a flexible pulse format, with pulse durations ranging from sub-femtoseconds to hundreds of femtoseconds.

  19. Synthesis of ultrawideband radiation of combined antenna arrays excited by nanosecond bipolar voltage pulses

    International Nuclear Information System (INIS)

    Koshelev, V I; Plisko, V V; Sevostyanov, E A

    2017-01-01

    To broaden the spectrum of high-power ultrawideband radiation, it is suggested to synthesize an electromagnetic pulse summing the pulses of different length in free space. On the example of model pulses corresponding to radiation of combined antennas excited by bipolar voltage pulses of the length of 2 and 3 ns, the possibility of twofold broadening of the radiation spectrum was demonstrated. Radiation pulses with the spectrum width exceeding three octaves were obtained. Pattern formation by the arrays of different geometry excited by the pulses having different time shifts was considered. Optimum array structure with the pattern maximum in the main direction was demonstrated on the example of a 2×2 array. (paper)

  20. Compact and multi-view solid state neutral particle analyzer arrays on National Spherical Torus Experiment-Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Liu, D., E-mail: deyongl@uci.edu; Heidbrink, W. W.; Hao, G. Z.; Zhu, Y. B. [Departments of Physics and Astronomy, University of California, Irvine, California 92697 (United States); Tritz, K. [Departments of Physics and Astronomy, Johns Hopkins University, Baltimore, Maryland 21218 (United States); Fredrickson, E. D. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States)

    2016-11-15

    A compact and multi-view solid state neutral particle analyzer (SSNPA) diagnostic based on silicon photodiode arrays has been successfully tested on the National Spherical Torus Experiment-Upgrade. The SSNPA diagnostic provides spatially, temporally, and pitch-angle resolved measurements of fast-ion distribution by detecting fast neutral flux resulting from the charge exchange (CX) reactions. The system consists of three 16-channel subsystems: t-SSNPA viewing the plasma mid-radius and neutral beam (NB) line #2 tangentially, r-SSNPA viewing the plasma core and NB line #1 radially, and p-SSNPA with no intersection with any NB lines. Due to the setup geometry, the active CX signals of t-SSNPA and r-SSNPA are mainly sensitive to passing and trapped particles, respectively. In addition, both t-SSNPA and r-SSNPA utilize three vertically stacked arrays with different filter thicknesses to obtain coarse energy information. The experimental data show that all channels are operational. The signal to noise ratio is typically larger than 10, and the main noise is x-ray induced signal. The active and passive CX signals are clearly observed on t-SSNPA and r-SSNPA during NB modulation. The SSNPA data also indicate significant losses of passing particles during sawteeth, while trapped particles are weakly affected. Fluctuations up to 120 kHz have been observed on SSNPA, and they are strongly correlated with magnetohydrodynamics instabilities.

  1. Concurrent array-based queue

    Science.gov (United States)

    Heidelberger, Philip; Steinmacher-Burow, Burkhard

    2015-01-06

    According to one embodiment, a method for implementing an array-based queue in memory of a memory system that includes a controller includes configuring, in the memory, metadata of the array-based queue. The configuring comprises defining, in metadata, an array start location in the memory for the array-based queue, defining, in the metadata, an array size for the array-based queue, defining, in the metadata, a queue top for the array-based queue and defining, in the metadata, a queue bottom for the array-based queue. The method also includes the controller serving a request for an operation on the queue, the request providing the location in the memory of the metadata of the queue.

  2. West Texas array experiment: Noise and source characterization of short-range infrasound and acoustic signals, along with lab and field evaluation of Intermountain Laboratories infrasound microphones

    Science.gov (United States)

    Fisher, Aileen

    The term infrasound describes atmospheric sound waves with frequencies below 20 Hz, while acoustics are classified within the audible range of 20 Hz to 20 kHz. Infrasound and acoustic monitoring in the scientific community is hampered by low signal-to-noise ratios and a limited number of studies on regional and short-range noise and source characterization. The JASON Report (2005) suggests the infrasound community focus on more broad-frequency, observational studies within a tactical distance of 10 km. In keeping with that recommendation, this paper presents a study of regional and short-range atmospheric acoustic and infrasonic noise characterization, at a desert site in West Texas, covering a broad frequency range of 0.2 to 100 Hz. To spatially sample the band, a large number of infrasound gauges was needed. A laboratory instrument analysis is presented of the set of low-cost infrasound sensors used in this study, manufactured by Inter-Mountain Laboratories (IML). Analysis includes spectra, transfer functions and coherences to assess the stability and range of the gauges, and complements additional instrument testing by Sandia National Laboratories. The IMLs documented here have been found reliably coherent from 0.1 to 7 Hz without instrument correction. Corrections were built using corresponding time series from the commercially available and more expensive Chaparral infrasound gauge, so that the corrected IML outputs were able to closely mimic the Chaparral output. Arrays of gauges are needed for atmospheric sound signal processing. Our West Texas experiment consisted of a 1.5 km aperture, 23-gauge infrasound/acoustic array of IMLs, with a compact, 12 m diameter grid-array of rented IMLs at the center. To optimize signal recording, signal-to-noise ratio needs to be quantified with respect to both frequency band and coherence length. The higher-frequency grid array consisted of 25 microphones arranged in a five by five pattern with 3 meter spacing, without

  3. Modulation infrared thermometry of caloric effects at up to kHz frequencies

    Science.gov (United States)

    Döntgen, Jago; Rudolph, Jörg; Waske, Anja; Hägele, Daniel

    2018-03-01

    We present a novel non-contact method for the direct measurement of caloric effects in low volume samples. The adiabatic temperature change ΔT of a magnetocaloric sample is very sensitively determined from thermal radiation. Rapid modulation of ΔT is induced by an oscillating external magnetic field. Detection of thermal radiation with a mercury-cadmium-telluride detector allows for measurements at field frequencies exceeding 1 kHz. In contrast to thermoacoustic methods, our method can be employed in vacuum which enhances adiabatic conditions especially in the case of small volume samples. Systematic measurements of the magnetocaloric effect as a function of temperature, magnetic field amplitude, and modulation frequency give a detailed picture of the thermal behavior of the sample. Highly sensitive measurements of the magnetocaloric effect are demonstrated on a 2 mm thick sample of gadolinium and a 60 μm thick Fe80B12Nb8 ribbon.

  4. Effects of fin pitch and array of the frost layer growth on extended surface of a heat exchanger

    International Nuclear Information System (INIS)

    Yang, Dong Keun; Lee, Kwan Soo

    2003-01-01

    This paper presents the effects of the fin array and pitch on the frost layer growth of a heat exchanger. The numerical results are compared with experimental data of a cold plate to validate the present model, and agree well with experimental data within a maximum error of 8%. The characteristics of the frost formation on staggered fin array are somewhat different from those of in-line array. For fin pitch below 10 mm, the frost layer growth of second fin in the staggered array is affected by that of first fin. The heat transfer of single fin deteriorate with decreasing fin pitch regardless of fin array, however, the thermal performance of a heat exchanger, considering increase of heat surface area, becomes better

  5. Low-Noise, UV-to-SWIR Broadband Photodiodes for Large-Format Focal Plane Array Sensors, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Broadband focal plane arrays, operating in UV-to-SWIR wavelength range, are required for atmospheric monitoring of greenhouse gases. Currently, separate image...

  6. Linear array of photodiodes to track a human speaker for video recording

    International Nuclear Information System (INIS)

    DeTone, D; Neal, H; Lougheed, R

    2012-01-01

    Communication and collaboration using stored digital media has garnered more interest by many areas of business, government and education in recent years. This is due primarily to improvements in the quality of cameras and speed of computers. An advantage of digital media is that it can serve as an effective alternative when physical interaction is not possible. Video recordings that allow for viewers to discern a presenter's facial features, lips and hand motions are more effective than videos that do not. To attain this, one must maintain a video capture in which the speaker occupies a significant portion of the captured pixels. However, camera operators are costly, and often do an imperfect job of tracking presenters in unrehearsed situations. This creates motivation for a robust, automated system that directs a video camera to follow a presenter as he or she walks anywhere in the front of a lecture hall or large conference room. Such a system is presented. The system consists of a commercial, off-the-shelf pan/tilt/zoom (PTZ) color video camera, a necklace of infrared LEDs and a linear photodiode array detector. Electronic output from the photodiode array is processed to generate the location of the LED necklace, which is worn by a human speaker. The computer controls the video camera movements to record video of the speaker. The speaker's vertical position and depth are assumed to remain relatively constant– the video camera is sent only panning (horizontal) movement commands. The LED necklace is flashed at 70Hz at a 50% duty cycle to provide noise-filtering capability. The benefit to using a photodiode array versus a standard video camera is its higher frame rate (4kHz vs. 60Hz). The higher frame rate allows for the filtering of infrared noise such as sunlight and indoor lighting–a capability absent from other tracking technologies. The system has been tested in a large lecture hall and is shown to be effective.

  7. Linear array of photodiodes to track a human speaker for video recording

    Science.gov (United States)

    DeTone, D.; Neal, H.; Lougheed, R.

    2012-12-01

    Communication and collaboration using stored digital media has garnered more interest by many areas of business, government and education in recent years. This is due primarily to improvements in the quality of cameras and speed of computers. An advantage of digital media is that it can serve as an effective alternative when physical interaction is not possible. Video recordings that allow for viewers to discern a presenter's facial features, lips and hand motions are more effective than videos that do not. To attain this, one must maintain a video capture in which the speaker occupies a significant portion of the captured pixels. However, camera operators are costly, and often do an imperfect job of tracking presenters in unrehearsed situations. This creates motivation for a robust, automated system that directs a video camera to follow a presenter as he or she walks anywhere in the front of a lecture hall or large conference room. Such a system is presented. The system consists of a commercial, off-the-shelf pan/tilt/zoom (PTZ) color video camera, a necklace of infrared LEDs and a linear photodiode array detector. Electronic output from the photodiode array is processed to generate the location of the LED necklace, which is worn by a human speaker. The computer controls the video camera movements to record video of the speaker. The speaker's vertical position and depth are assumed to remain relatively constant- the video camera is sent only panning (horizontal) movement commands. The LED necklace is flashed at 70Hz at a 50% duty cycle to provide noise-filtering capability. The benefit to using a photodiode array versus a standard video camera is its higher frame rate (4kHz vs. 60Hz). The higher frame rate allows for the filtering of infrared noise such as sunlight and indoor lighting-a capability absent from other tracking technologies. The system has been tested in a large lecture hall and is shown to be effective.

  8. Design and Assembly of DNA Nano-Objects and 2D DNA Origami Arrays

    Science.gov (United States)

    Liu, Wenyan

    DNA, which plays a central role in biology as the carrier of genetic information, is also an excellent candidate for structural nanotechnology. Researches have proven that a variety of complicated DNA assemblies, such as objects, 2D & 3D crystals, and nanomechanical devices, can be fabricated through the combination of robust branched DNA motifs and sticky ends. This dissertation focuses on the design and construction of DNA nano--objects and 2D DNA origami arrays. In this dissertation, we first describe the formation of a triangular species that has four strands per edge, held together by PX interactions. We demonstrate by nondenaturing gel electrophoresis and by atomic force microscopy (AFM) that we can combine a partial triangle with other strands to form a robust four--stranded molecule. By combining them with a novel three--domain molecule, we also demonstrate by AFM that these triangles can be self--assembled into a linear array. Second, we demonstrate our attempts to design and self--assemble 2D DNA origami arrays using several different strategies. Specifically, we introduce the self--assembly of 2D DNA origami lattices using a symmetric cross--like design. This design strategy resulted in a well--ordered woven latticework array with edge dimensions of 2--3 mum. This size is likely to be large enough to connect bottom-up methods of patterning with top--down approaches. Third, we illustrate the design and construction of DNA nano--objects for exploring the substrate preferences of topoisomerase (topo) II. We designed and fabricated four double rhombus--like DNA molecules, each of which contains a different conformation of crossover in the middle, as possible substrates to establish the structural preferences for topo II. We characterized the formation of each substrate molecule by gel electrophoresis. Finally, we study the effect of M13 DNA knotting on the formation of the DNA origami tiles. We demonstrate by atomic force microscopy (AFM) that knotted M13

  9. Frontiers of Radio Astronomy in the 2020s: The Next Generation Very Large Array

    Science.gov (United States)

    Murphy, Eric Joseph; ngVLA Project Office, ngVLA Science and Technical Advisory Councils, ngVLA Science Working Groups

    2018-01-01

    This talk will describe the current community-driven science goals, design, and planning status of a future large centimeter radio array: the ‘Next Generation Very Large Array’ (ngVLA). The ngVLA is being developed to observe at wavelengths between ALMA at submm wavelengths, and the future SKA-1 at few centimeter and longer wavelengths, opening a new window on the Universe through ultra-sensitive imaging of thermal line and continuum emission down to milliarcsecond resolution, and unprecedented broad band continuum polarimetric imaging of non-thermal processes. The current design for the array includes 10x more effective collecting area and 10x higher spatial resolution than the current JVLA or ALMA, carefully optimized for operation in the frequency range 10GHz to 50GHz, while still delivering world-leading sensitivity over the entire 1.2GHz to 116 GHz spectrum.With this array, new frontiers in modern astronomy can be reached, including direct imaging and chemical analysis of planet formation in the terrestrial-zone of nearby stars, studies of dust-obscured star formation and the cosmic baryon cycle down to pc-scales in the local Universe, and detailed imaging of molecular gas and galaxy formation into the epoch of reionization. Novel techniques for exploring temporal phenomena on timescales from milliseconds to years will also be implemented. The ngVLA will be situated in the desert southwest of the United States, centered on the current JVLA infrastructure, with multiple antennas anticipated in states/regions adjacent to NM, and in northern Mexico.A recently formed Project Office is working closely with the U.S. and international research community to design the array, and plan its construction beginning mid next decade. Recent significant funding for design and development brought forward by the NSF will enable detailed science case development and technology prototyping/risk reduction before the next U.S astronomy Decadal Survey.

  10. Realistic full wave modeling of focal plane array pixels.

    Energy Technology Data Exchange (ETDEWEB)

    Campione, Salvatore [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States). Electromagnetic Theory Dept.; Warne, Larry K. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States). Electromagnetic Theory Dept.; Jorgenson, Roy E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States). Electromagnetic Theory Dept.; Davids, Paul [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States). Applied Photonic Microsystems Dept.; Peters, David W. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States). Applied Photonic Microsystems Dept.

    2017-11-01

    Here, we investigate full-wave simulations of realistic implementations of multifunctional nanoantenna enabled detectors (NEDs). We focus on a 2x2 pixelated array structure that supports two wavelengths of operation. We design each resonating structure independently using full-wave simulations with periodic boundary conditions mimicking the whole infinite array. We then construct a supercell made of a 2x2 pixelated array with periodic boundary conditions mimicking the full NED; in this case, however, each pixel comprises 10-20 antennas per side. In this way, the cross-talk between contiguous pixels is accounted for in our simulations. We observe that, even though there are finite extent effects, the pixels work as designed, each responding at the respective wavelength of operation. This allows us to stress that realistic simulations of multifunctional NEDs need to be performed to verify the design functionality by taking into account finite extent and cross-talk effects.

  11. Flat-plate solar array project. Volume 1: Executive summary

    Science.gov (United States)

    Callaghan, W.; Mcdonald, R.

    1986-01-01

    In 1975, the U.S. Government contracted the Jet Propulsion Lab. to develop, by 1985, in conjunction with industry, the photovoltaics (PV) module and array technology required for widespread use of photovoltaics as a significant terrestrial energy source. As a result, a project that eventually became known as the Flat Plate Solar Array (FSA) Project was formed to manage an industry, university, and Government team to perform the necessary research and development. The original goals were to achieve widespread commercial use of PV modules and arrays through the development of technology that would allow them to be profitably sold for $1.07/peak watts (1985 dollars). A 10% module conversion efficiency and a 20 year lifetime were also goals. It is intended that the executive summary provide the means by which one can gain a perspective on 11 years of terrestrial photovoltaic research and development conducted by the FSA Project.

  12. Programmable cellular arrays. Faults testing and correcting in cellular arrays

    International Nuclear Information System (INIS)

    Cercel, L.

    1978-03-01

    A review of some recent researches about programmable cellular arrays in computing and digital processing of information systems is presented, and includes both combinational and sequential arrays, with full arbitrary behaviour, or which can realize better implementations of specialized blocks as: arithmetic units, counters, comparators, control systems, memory blocks, etc. Also, the paper presents applications of cellular arrays in microprogramming, in implementing of a specialized computer for matrix operations, in modeling of universal computing systems. The last section deals with problems of fault testing and correcting in cellular arrays. (author)

  13. Noiseless imaging detector for adaptive optics with kHz frame rates

    CERN Document Server

    Vallerga, J V; Mikulec, Bettina; Tremsin, A; Clark, Allan G; Siegmund, O H W; CERN. Geneva

    2004-01-01

    A new hybrid optical detector is described that has many of the attributes desired for the next generation AO wavefront sensors. The detector consists of a proximity focused MCP read out by four multi-pixel application specific integrated circuit (ASIC) chips developed at CERN (â€ワMedipix2”) with individual pixels that amplify, discriminate and count input events. The detector has 512 x 512 pixels, zero readout noise (photon counting) and can be read out at 1 kHz frame rates. The Medipix2 readout chips can be electronically shuttered down to a temporal window of a few microseconds with an accuracy of 10 nanoseconds. When used in a Shack-Hartman style wavefront sensor, it should be able to centroid approximately 5000 spots using 7 x 7 pixel sub-apertures resulting in very linear, off-null error correction terms. The quantum efficiency depends on the optical photocathode chosen for the bandpass of interest. A three year development effort for this detector technology has just been funded as part of the...

  14. Pulse-echo phased array ultrasonic inspection of pultruded rod stitched efficient unitized structure (PRSEUS)

    International Nuclear Information System (INIS)

    Johnston, P. H.

    2011-01-01

    A PRSEUS test article was subjected to controlled impact on the skin face followed by static and cyclic axial compressions. Phased array ultrasonic inspection was conducted before impact, and after each of the test conditions. A linear phased array probe with a manual X-Y scanner was used for interrogation. Ultrasound showed a delamination between the skin and stringer flange adjacent to the impact. As designed, the stitching in the flange arrested the lateral flaw formation. Subsequent ultrasonic data showed no delamination growth due to continued loading.

  15. Aligned gold nanoneedle arrays for surface-enhanced Raman scattering

    International Nuclear Information System (INIS)

    Yang Yong; Huang Zhengren; Jiang Dongliang; Tanemura, Masaki; Yamaguchi, Kohei; Li Zhiyuan; Huang Yingping; Kawamura, Go; Nogami, Masayuki

    2010-01-01

    A simple Ar + -ion irradiation route has been developed to prepare gold nanoneedle arrays on glass substrates for surface-enhanced Raman scattering (SERS)-active substrates. The nanoneedles exhibited very sharp tips with an apex diameter of 20 nm. These arrays were evaluated as potential SERS substrates using malachite green molecules and exhibited a SERS enhancement factor of greater than 10 8 , which is attributed to the localized electron field enhancement around the apex of the needle and the surface plasmon coupling originating from the periodic structure. This work demonstrates a new technique for producing controllable and reproducible SERS substrates potentially applicable for chemical and biological assays.

  16. NEMO-SMO acoustic array: A deep-sea test of a novel acoustic positioning system for a km3-scale underwater neutrino telescope

    Science.gov (United States)

    Viola, S.; Ardid, M.; Bertin, V.; Enzenhöfer, A.; Keller, P.; Lahmann, R.; Larosa, G.; Llorens, C. D.; NEMO Collaboration; SMO Collaboration

    2013-10-01

    Within the activities of the NEMO project, the installation of a 8-floors tower (NEMO-Phase II) at a depth of 3500 m is foreseen in 2012. The tower will be installed about 80 km off-shore Capo Passero, in Sicily. On board the NEMO tower, an array of 18 acoustic sensors will be installed, permitting acoustic detection of biological sources, studies for acoustic neutrino detection and primarily acoustic positioning of the underwater structures. For the latter purpose, the sensors register acoustic signals emitted by five acoustic beacons anchored on the sea-floor. The data acquisition system of the acoustic sensors is fully integrated with the detector data transport system and is based on an “all data to shore” philosophy. Signals coming from hydrophones are continuously sampled underwater at 192 kHz/24 bit and transmitted to shore through an electro-optical cable for real-time analysis. A novel technology for underwater GPS time-stamping of data has been implemented and tested. The operation of the acoustic array will permit long-term test of sensors and electronics technologies that are proposed for the acoustic positioning system of KM3NeT.

  17. Effect of discrete wires on the implosion dynamics of wire array Z pinches

    International Nuclear Information System (INIS)

    Lebedev, S. V.; Beg, F. N.; Bland, S. N.; Chittenden, J. P.; Dangor, A. E.; Haines, M. G.; Kwek, K. H.; Pikuz, S. A.; Shelkovenko, T. A.

    2001-01-01

    A phenomenological model of wire array Z-pinch implosions, based on the analysis of experimental data obtained on the mega-ampere generator for plasma implosion experiments (MAGPIE) generator [I. H. Mitchell , Rev. Sci. Instrum. 67, 1533 (1996)], is described. The data show that during the first ∼80% of the implosion the wire cores remain stationary in their initial positions, while the coronal plasma is continuously jetting from the wire cores to the array axis. This phase ends by the formation of gaps in the wire cores, which occurs due to the nonuniformity of the ablation rate along the wires. The final phase of the implosion starting at this time occurs as a rapid snowplow-like implosion of the radially distributed precursor plasma, previously injected in the interior of the array. The density distribution of the precursor plasma, being peaked on the array axis, could be a key factor providing stability of the wire array implosions operating in the regime of discrete wires. The modified ''initial'' conditions for simulations of wire array Z-pinch implosions with one-dimension (1D) and two-dimensions (2D) in the r--z plane, radiation-magnetohydrodynamic (MHD) codes, and a possible scaling to a larger drive current are discussed

  18. Colloidal silica films for high-capacity DNA arrays

    Science.gov (United States)

    Glazer, Marc Irving

    The human genome project has greatly expanded the amount of genetic information available to researchers, but before this vast new source of data can be fully utilized, techniques for rapid, large-scale analysis of DNA and RNA must continue to develop. DNA arrays have emerged as a powerful new technology for analyzing genomic samples in a highly parallel format. The detection sensitivity of these arrays is dependent on the quantity and density of immobilized probe molecules. We have investigated substrates with a porous, "three-dimensional" surface layer as a means of increasing the surface area available for the synthesis of oligonucleotide probes, thereby increasing the number of available probes and the amount of detectable bound target. Porous colloidal silica films were created by two techniques. In the first approach, films were deposited by spin-coating silica colloid suspensions onto flat glass substrates, with the pores being formed by the natural voids between the solid particles (typically 23nm pores, 35% porosity). In the second approach, latex particles were co-deposited with the silica and then pyrolyzed, creating films with larger pores (36 nm), higher porosity (65%), and higher surface area. For 0.3 mum films, enhancements of eight to ten-fold and 12- to 14-fold were achieved with the pure silica films and the films "templated" with polymer latex, respectively. In gene expression assays for up to 7,000 genes using complex biological samples, the high-capacity films provided enhanced signals and performed equivalently or better than planar glass on all other functional measures, confirming that colloidal silica films are a promising platform for high-capacity DNA arrays. We have also investigated the kinetics of hybridization on planar glass and high-capacity substrates. Adsorption on planar arrays is similar to ideal Langmuir-type adsorption, although with an "overshoot" at high solution concentration. Hybridization on high-capacity films is

  19. Genetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array--comparative genomic hybridization

    DEFF Research Database (Denmark)

    Isinger-Ekstrand, Anna; Johansson, Jan; Ohlsson, Mattias

    2010-01-01

    15, 13q34, and 12q13, whereas different profiles with gains at 5p15, 7p22, 2q35, and 13q34 characterized gastric cancers. CDK6 and EGFR were identified as putative target genes in cancers of the esophagus and the gastroesophageal junction, with upregulation in one quarter of the tumors. Gains......We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high......-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative target genes were validated in an extended series. Adenocarcinomas in the distal esophagus and the gastroesophageal junction showed strong similarities with the most common gains at 20q13, 8q24, 1q21-23, 5p...

  20. Ultradense, Deep Subwavelength Nanowire Array Photovoltaics As Engineered Optical Thin Films

    KAUST Repository

    Tham, Douglas

    2010-11-10

    A photovoltaic device comprised of an array of 20 nm wide, 32 nm pitch array of silicon nanowires is modeled as an optical material. The nanowire array (NWA) has characteristic device features that are deep in the subwavelength regime for light, which permits a number of simplifying approximations. Using photocurrent measurements as a probe of the absorptance, we show that the NWA optical properties can be accurately modeled with rigorous coupled-wave analysis. The densely structured NWAs behave as homogeneous birefringent materials into the ultraviolet with effective optical properties that are accurately modeled using the dielectric functions of bulk Si and SiO 2, coupled with a physical model for the NWA derived from ellipsometry and transmission electron microscopy. © 2010 American Chemical Society.

  1. Decreased interleukin-20 expression in scleroderma skin contributes to cutaneous fibrosis.

    Science.gov (United States)

    Kudo, Hideo; Jinnin, Masatoshi; Asano, Yoshihide; Trojanowska, Maria; Nakayama, Wakana; Inoue, Kuniko; Honda, Noritoshi; Kajihara, Ikko; Makino, Katsunari; Fukushima, Satoshi; Ihn, Hironobu

    2014-06-01

    To clarify the role of interleukin-20 (IL-20) in the regulatory mechanism of extracellular matrix expression and to determine the contribution of IL-20 to the phenotype of systemic sclerosis (SSc). Protein and messenger RNA (mRNA) levels of collagen, Fli-1, IL-20, and IL-20 receptor (IL-20R) were analyzed using polymerase chain reaction (PCR) array, immunoblotting, immunohistochemical staining, enzyme-linked immunosorbent assay, and real-time PCR. PCR array revealed that IL-20 decreased gene expression of α2(I) collagen (0.03-fold), Smad3 (0.02-fold), and endoglin (0.05-fold) in cultured normal dermal fibroblasts. Fli-1 protein expression was induced by IL-20 (~2-fold). The inhibition of collagen by IL-20, the induction of Fli-1 by IL-20, and the reduction of Smad3 and endoglin by IL-20 were also observed in SSc fibroblasts. Serum IL-20 levels were reduced only slightly in SSc patients but were significantly decreased in patients with scleroderma spectrum disorders (the prodromal stage of SSc) compared with those in normal subjects (111.3 pg/ml versus 180.4 pg/ml; P value of IL-20 and IL-20R, their function and expression in vivo should be further studied. Copyright © 2014 by the American College of Rheumatology.

  2. CGHPRO – A comprehensive data analysis tool for array CGH

    Directory of Open Access Journals (Sweden)

    Lenzner Steffen

    2005-04-01

    Full Text Available Abstract Background Array CGH (Comparative Genomic Hybridisation is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the co-hybridisation of differentially labelled test and reference DNA onto arrays of genomic BAC clones, cDNAs or oligonucleotides, and after correction for various intervening variables, loss or gain in the test DNA can be indicated from spots showing aberrant signal intensity ratios. Now that this technique is no longer confined to highly specialized laboratories and is entering the realm of clinical application, there is a need for a user-friendly software package that facilitates estimates of DNA dosage from raw signal intensities obtained by array CGH experiments, and which does not depend on a sophisticated computational environment. Results We have developed a user-friendly and versatile tool for the normalization, visualization, breakpoint detection and comparative analysis of array-CGH data. CGHPRO is a stand-alone JAVA application that guides the user through the whole process of data analysis. The import option for image analysis data covers several data formats, but users can also customize their own data formats. Several graphical representation tools assist in the selection of the appropriate normalization method. Intensity ratios of each clone can be plotted in a size-dependent manner along the chromosome ideograms. The interactive graphical interface offers the chance to explore the characteristics of each clone, such as the involvement of the clones sequence in segmental duplications. Circular Binary Segmentation and unsupervised Hidden Markov Model algorithms facilitate objective detection of chromosomal breakpoints. The storage of all essential data in a back-end database allows the simultaneously comparative analysis of different cases. The various display options facilitate also the definition of shortest regions of overlap and simplify the

  3. Airfoil-based electromagnetic energy harvester containing parallel array motion between moving coil and multi-pole magnets towards enhanced power density.

    Science.gov (United States)

    Leung, Chung Ming; Wang, Ya; Chen, Wusi

    2016-11-01

    In this letter, the airfoil-based electromagnetic energy harvester containing parallel array motion between moving coil and trajectory matching multi-pole magnets was investigated. The magnets were aligned in an alternatively magnetized formation of 6 magnets to explore enhanced power density. In particular, the magnet array was positioned in parallel to the trajectory of the tip coil within its tip deflection span. The finite element simulations of the magnetic flux density and induced voltages at an open circuit condition were studied to find the maximum number of alternatively magnetized magnets that was required for the proposed energy harvester. Experimental results showed that the energy harvester with a pair of 6 alternatively magnetized linear magnet arrays was able to generate an induced voltage (V o ) of 20 V, with an open circuit condition, and 475 mW, under a 30 Ω optimal resistance load operating with the wind speed (U) at 7 m/s and a natural bending frequency of 3.54 Hz. Compared to the traditional electromagnetic energy harvester with a single magnet moving through a coil, the proposed energy harvester, containing multi-pole magnets and parallel array motion, enables the moving coil to accumulate a stronger magnetic flux in each period of the swinging motion. In addition to the comparison made with the airfoil-based piezoelectric energy harvester of the same size, our proposed electromagnetic energy harvester generates 11 times more power output, which is more suitable for high-power-density energy harvesting applications at regions with low environmental frequency.

  4. Micromirror Arrays for Adaptive Optics; TOPICAL

    International Nuclear Information System (INIS)

    Carr, E.J.

    2000-01-01

    The long-range goal of this project is to develop the optical and mechanical design of a micromirror array for adaptive optics that will meet the following criteria: flat mirror surface ((lambda)/20), high fill factor ( and gt; 95%), large stroke (5-10(micro)m), and pixel size(approx)-200(micro)m. This will be accomplished by optimizing the mirror surface and actuators independently and then combining them using bonding technologies that are currently being developed

  5. Patterned Array of Poly(ethylene glycol Silane Monolayer for Label-Free Detection of Dengue

    Directory of Open Access Journals (Sweden)

    Nor Zida Rosly

    2016-08-01

    Full Text Available In the present study, the construction of arrays on silicon for naked-eye detection of DNA dengue was demonstrated. The array was created by exposing a polyethylene glycol (PEG silane monolayer to 254 nm ultraviolet (UV light through a photomask. Formation of the PEG silane monolayer and photomodifed surface properties was thoroughly characterized by using atomic force microscopy (AFM, X-ray photoelectron spectroscopy (XPS, and contact angle measurements. The results of XPS confirmed that irradiation of ultraviolet (UV light generates an aldehyde functional group that offers conjugation sites of amino DNA probe for detection of a specific dengue virus target DNA. Employing a gold enhancement process after inducing the electrostatic interaction between positively charged gold nanoparticles and the negatively charged target DNA hybridized to the DNA capture probe allowed to visualize the array with naked eye. The developed arrays demonstrated excellent performance in diagnosis of dengue with a detection limit as low as 10 pM. The selectivity of DNA arrays was also examined using a single base mismatch and noncomplementary target DNA.

  6. Riems influenza a typing array (RITA): An RT-qPCR-based low density array for subtyping avian and mammalian influenza a viruses.

    Science.gov (United States)

    Hoffmann, Bernd; Hoffmann, Donata; Henritzi, Dinah; Beer, Martin; Harder, Timm C

    2016-06-03

    Rapid and sensitive diagnostic approaches are of the utmost importance for the detection of humans and animals infected by specific influenza virus subtype(s). Cascade-like diagnostics starting with the use of pan-influenza assays and subsequent subtyping devices are normally used. Here, we demonstrated a novel low density array combining 32 TaqMan(®) real-time RT-PCR systems in parallel for the specific detection of the haemagglutinin (HA) and neuraminidase (NA) subtypes of avian and porcine hosts. The sensitivity of the newly developed system was compared with that of the pan-influenza assay, and the specificity of all RT-qPCRs was examined using a broad panel of 404 different influenza A virus isolates representing 45 different subtypes. Furthermore, we analysed the performance of the RT-qPCR assays with diagnostic samples obtained from wild birds and swine. Due to the open format of the array, adaptations to detect newly emerging influenza A virus strains can easily be integrated. The RITA array represents a competitive, fast and sensitive subtyping tool that requires neither new machinery nor additional training of staff in a lab where RT-qPCR is already established.

  7. The Digital Motion Control System for the Submillimeter Array Antennas

    Science.gov (United States)

    Hunter, T. R.; Wilson, R. W.; Kimberk, R.; Leiker, P. S.; Patel, N. A.; Blundell, R.; Christensen, R. D.; Diven, A. R.; Maute, J.; Plante, R. J.; Riddle, P.; Young, K. H.

    2013-09-01

    We describe the design and performance of the digital servo and motion control system for the 6-meter parabolic antennas of the Submillimeter Array (SMA) on Mauna Kea, Hawaii. The system is divided into three nested layers operating at a different, appropriate bandwidth. (1) A rack-mounted, real-time Unix system runs the position loop which reads the high resolution azimuth and elevation encoders and sends velocity and acceleration commands at 100 Hz to a custom-designed servo control board (SCB). (2) The microcontroller-based SCB reads the motor axis tachometers and implements the velocity loop by sending torque commands to the motor amplifiers at 558 Hz. (3) The motor amplifiers implement the torque loop by monitoring and sending current to the three-phase brushless drive motors at 20 kHz. The velocity loop uses a traditional proportional-integral-derivative (PID) control algorithm, while the position loop uses only a proportional term and implements a command shaper based on the Gauss error function. Calibration factors and software filters are applied to the tachometer feedback prior to the application of the servo gains in the torque computations. All of these parameters are remotely adjustable in the software. The three layers of the control system monitor each other and are capable of shutting down the system safely if a failure or anomaly occurs. The Unix system continuously relays the antenna status to the central observatory computer via reflective memory. In each antenna, a Palm Vx hand controller displays the complete system status and allows full local control of the drives in an intuitive touchscreen user interface. The hand controller can also be connected outside the cabin, a major convenience during the frequent reconfigurations of the interferometer. Excellent tracking performance ( 0.3‧‧ rms) is achieved with this system. It has been in reliable operation on 8 antennas for over 10 years and has required minimal maintenance.

  8. Primary Dendrite Array Morphology: Observations from Ground-based and Space Station Processed Samples

    Science.gov (United States)

    Tewari, Surendra; Rajamure, Ravi; Grugel, Richard; Erdmann, Robert; Poirier, David

    2012-01-01

    Influence of natural convection on primary dendrite array morphology during directional solidification is being investigated under a collaborative European Space Agency-NASA joint research program, "Microstructure Formation in Castings of Technical Alloys under Diffusive and Magnetically Controlled Convective Conditions (MICAST)". Two Aluminum-7 wt pct Silicon alloy samples, MICAST6 and MICAST7, were directionally solidified in microgravity on the International Space Station. Terrestrially grown dendritic monocrystal cylindrical samples were remelted and directionally solidified at 18 K/cm (MICAST6) and 28 K/cm (MICAST7). Directional solidification involved a growth speed step increase (MICAST6-from 5 to 50 micron/s) and a speed decrease (MICAST7-from 20 to 10 micron/s). Distribution and morphology of primary dendrites is currently being characterized in these samples, and also in samples solidified on earth under nominally similar thermal gradients and growth speeds. Primary dendrite spacing and trunk diameter measurements from this investigation will be presented.

  9. The Milano-Gran Sasso double beta decay experiment: toward a 20-crystal array

    International Nuclear Information System (INIS)

    Alessandrello, A.; Brofferio, C.; Bucci, C.; Cremonesi, O.; Fiorini, E.; Giuliani, A.; Nucciotti, A.; Pavan, M.; Pessina, G.; Previtali, E.; Zanotti, L.

    1996-01-01

    TeO 2 thermal detectors are being used by the Milano group to search for neutrinoless double beta decay of 130 Te. An upper limit for neutrinoless decay half life of 2.1 x 10 22 yr at 90% CL obtained with a 334 g TeO 2 detector has been previously reported. To improve the sensitivity of the experiment an array of twenty 340 g TeO 2 crystals will be realised in the next future. As a first step toward the realisation of that experiment a 4 crystal detector has been tested in the Gran Sasso refrigerator. Detector performances, data acquisition and analysis are discussed. (orig.)

  10. MIMO Communication Using Single Feed Antenna Arrays

    DEFF Research Database (Denmark)

    Alrabadi, Osama

    Multi-input-multi-output (MIMO) communication has emerged as a promis- ing technology for meeting the increasing demand on higher data rates. The technology exploits the spatial resource dimension by sending the datas- treams to different locations in the multi element array (MEA) domain while...... conventionally to a single antenna element while mod- ulating the other datastreams in the analogue RF domain, using simple switched antenna systems (SAS) or sophisticated reactance-assisted antenna systems. The use of a SAS is found simple to implement, but can hardly handle high order signal formats...

  11. Protein kinase substrate identification on functional protein arrays

    Directory of Open Access Journals (Sweden)

    Zhou Fang

    2008-02-01

    Full Text Available Abstract Background Over the last decade, kinases have emerged as attractive therapeutic targets for a number of different diseases, and numerous high throughput screening efforts in the pharmaceutical community are directed towards discovery of compounds that regulate kinase function. The emerging utility of systems biology approaches has necessitated the development of multiplex tools suitable for proteomic-scale experiments to replace lower throughput technologies such as mass spectroscopy for the study of protein phosphorylation. Recently, a new approach for identifying substrates of protein kinases has applied the miniaturized format of functional protein arrays to characterize phosphorylation for thousands of candidate protein substrates in a single experiment. This method involves the addition of protein kinases in solution to arrays of immobilized proteins to identify substrates using highly sensitive radioactive detection and hit identification algorithms. Results To date, the factors required for optimal performance of protein array-based kinase substrate identification have not been described. In the current study, we have carried out a detailed characterization of the protein array-based method for kinase substrate identification, including an examination of the effects of time, buffer compositions, and protein concentration on the results. The protein array approach was compared to standard solution-based assays for assessing substrate phosphorylation, and a correlation of greater than 80% was observed. The results presented here demonstrate how novel substrates for protein kinases can be quickly identified from arrays containing thousands of human proteins to provide new clues to protein kinase function. In addition, a pooling-deconvolution strategy was developed and applied that enhances characterization of specific kinase-substrate relationships and decreases reagent consumption. Conclusion Functional protein microarrays are an

  12. Fabrication of three-dimensional ordered nanodot array structures by a thermal dewetting method

    International Nuclear Information System (INIS)

    Li Zhenxing; Yoshino, Masahiko; Yamanaka, Akinori

    2012-01-01

    A new fabrication method for three-dimensional nanodot arrays with low cost and high throughput is developed in this paper. In this process, firstly a 2D nanodot array is fabricated by combination of top-down and bottom-up approaches. A nanoplastic forming technique is utilized as the top-down approach to fabricate a groove grid pattern on an Au layer deposited on a substrate, and self-organization by thermal dewetting is employed as the bottom-up approach. On the first-layer nanodot array, SiO 2 is deposited as a spacer layer. Au is then deposited on the spacer layer and thermal dewetting is conducted to fabricate a second-layer nanodot array. The effective parameters influencing dot formation on the second layer, including Au layer thickness and SiO 2 layer thickness, are studied. It is demonstrated that a 3D nanodot array of good vertical alignment is obtained by repeating the SiO 2 deposition, Au deposition and thermal dewetting. The mechanism of the dot agglomeration process is studied based on geometrical models. The effects of the spacer layer thickness and Au layer thickness on the morphology and alignment of the second-layer dots are discussed. (paper)

  13. Computer-assisted time-averaged holograms of the motion of the surface of the mammalian tympanic membrane with sound stimuli of 0.4-25 kHz.

    Science.gov (United States)

    Rosowski, John J; Cheng, Jeffrey Tao; Ravicz, Michael E; Hulli, Nesim; Hernandez-Montes, Maria; Harrington, Ellery; Furlong, Cosme

    2009-07-01

    Time-averaged holograms describing the sound-induced motion of the tympanic membrane (TM) in cadaveric preparations from three mammalian species and one live ear were measured using opto-electronic holography. This technique allows rapid measurements of the magnitude of motion of the tympanic membrane surface at frequencies as high as 25 kHz. The holograms measured in response to low and middle-frequency sound stimuli are similar to previously reported time-averaged holograms. However, at higher frequencies (f>4 kHz), our holograms reveal unique TM surface displacement patterns that consist of highly-ordered arrangements of multiple local displacement magnitude maxima, each of which is surrounded by nodal areas of low displacement magnitude. These patterns are similar to modal patterns (two-dimensional standing waves) produced by either the interaction of surface waves traveling in multiple directions or the uniform stimulation of modes of motion that are determined by the structural properties and boundary conditions of the TM. From the ratio of the displacement magnitude peaks to nodal valleys in these apparent surface waves, we estimate a Standing Wave Ratio of at least 4 that is consistent with energy reflection coefficients at the TM boundaries of at least 0.35. It is also consistent with small losses within the uniformly stimulated modal surface waves. We also estimate possible TM surface wave speeds that vary with frequency and species from 20 to 65 m/s, consistent with other estimates in the literature. The presence of standing wave or modal phenomena has previously been intuited from measurements of TM function, but is ignored in some models of tympanic membrane function. Whether these standing waves result either from the interactions of multiple surface waves that travel along the membrane, or by uniformly excited modal displacement patterns of the entire TM surface is still to be determined.

  14. Glass formation ability, structure and magnetocaloric effect of a heavy rare-earth bulk metallic glassy Gd{sub 55}Co{sub 20}Fe{sub 5}Al{sub 20} alloy

    Energy Technology Data Exchange (ETDEWEB)

    Jo, C.-L. [Shanghai University, School of Materials Science and Engineering, Yanchang Road 149, Zhabei District, 200072 Shanghai (China)], E-mail: jochollong@163.com; Xia Lei; Ding Ding; Dong Yuanda; Gracien, Ekoko [Shanghai University, School of Materials Science and Engineering, Yanchang Road 149, Zhabei District, 200072 Shanghai (China)

    2008-06-30

    The glass formation ability, the structure and the magnetocaloric effect of the bulk metallic glassy Gd{sub 55}Co{sub 20}Fe{sub 5}Al{sub 20} alloy were investigated. Bulk metallic glassy (BMGs) alloys were prepared by a copper-mold casting method. The glass forming ability and their structure were studied by using X-ray diffraction (XRD) and differential scanning calorimeter (DSC). The XRD analysis revealed that the as-cast cylinder of Gd{sub 55}Co{sub 20}Fe{sub 5}Al{sub 20} alloy showed fully amorphous structure in 2 mm diameter. The DSC revealed that the bulk cylinder of the Gd{sub 55}Co{sub 20}Fe{sub 5}Al{sub 20} alloy showed a distinct glass transition temperature and a relatively wide supercooled liquid region before crystallization. SQUID investigated the magnetic properties and the entropy changes. The Curie temperature of Gd{sub 55}Co{sub 20}Fe{sub 5}Al{sub 20} BMGs alloy was about 130 K, but the maximum magnetic entropy changes(-{delta}S{sub M}) showed at about 125 K, a little lower than the Curie temperature 130 K. The reason could probably be due to the presence of a little amount of nanocrystalline particles between amorphous phases. The BMG alloy has the characteristic of second-order transition (SOT) on Arrott plots. The results showed that the amorphous sample had a relatively improved magnetocaloric effect, indicating that the amorphous alloy could be considered as a candidate for magnetic refrigeration applications in the temperature interval range of 100-200 K.

  15. Demonstration of Millimeter Wave 5G Setup Employing High-Gain Vivaldi Array

    Directory of Open Access Journals (Sweden)

    Waleed Tariq Sethi

    2018-01-01

    Full Text Available We present a 4 × 4 slot-coupled Vivaldi antenna (SCVA array unit cell, which offers wide bandwidth and high gain (~23 dBi at the millimeter wave (mmW frequencies of 28 GHz and 38 GHz. A single SCVA element is first presented, which has a bandwidth of 25–40 GHz with an average gain of ~13 dBi at the frequencies of interest. This antenna element is then used to design a 1 × 4 linear SCVA array matched to a 50 Ω impedance via a modified Wilkinson power divider (WPD. Next, the 1 × 4 linear array is used to construct a 4 × 4 antenna array unit cell. The proposed 4 × 4 antenna array unit cell is fabricated, and the characteristics of its elements (i.e., the single SCVA, 1 × 4 linear array, and WPD are thoroughly investigated. Further, the 4 × 4 array is tested for signal reception of various digital modulation formats at lab environment using high-speed digital signal oscilloscope. In particular, a 2.5 Gbps data rate is successfully transmitted achieving receiver sensitivity of −50 dBm at 2 × 10−3 bit error rate (BER for 32 quadrature amplitude modulation (QAM with a system baud rate of 500 MHz. The wide bandwidth and high gain along with the excellent performance of the proposed 4 × 4 antenna array unit cell makes it an excellent candidate for future 5G wireless communication applications.

  16. Silicon PIN diode hybrid arrays for charged particle detection: Building blocks for vertex detectors at the SSC

    International Nuclear Information System (INIS)

    Kramer, G.; Gaalema, S.; Shapiro, S.L.; Dunwoodie, W.M.; Arens, J.F.; Jernigan, J.G.

    1989-05-01

    Two-dimensional arrays of solid state detectors have long been used in visible and infrared systems. Hybrid arrays with separately optimized detector and readout substrates have been extensively developed for infrared sensors. The characteristics and use of these infrared readout chips with silicon PIN diode arrays produced by MICRON SEMICONDUCTOR for detecting high-energy particles are reported. Some of these arrays have been produced in formats as large as 512 /times/ 512 pixels; others have been radiation hardened to total dose levels beyond 1 Mrad. Data generation rates of 380 megasamples/second have been achieved. Analog and digital signal transmission and processing techniques have also been developed to accept and reduce these high data rates. 9 refs., 15 figs., 2 tabs

  17. Electromagnetic field measurements in ULF-ELF-VLF [0.001 Hz─100 KHz] bands

    Directory of Open Access Journals (Sweden)

    C. Di Lorenzo

    2008-01-01

    Full Text Available We are reporting the technological and scientific objectives of the MEM project. The MEM project has been activated in the INGV Observatory of L'Aquila to create in Central Italy a network of observatories in order to monitoring the electromagnetic signals in the frequency band [0.001 Hz–100 kHz]. Some examples of the instrumentation developed in the frame of the project are reported. An innovative technique, based on the wide band interferometry is proposed to obtain detailed information concerning the several detected electromagnetic sources. Moreover, data from each station will be elaborated to investigate different sectors as the structure of ground electric conductibility, the electromagnetic phenomena connected with seismic activity, the separation of the electromagnetic fields originated in the Earth's interior and the electromagnetic phenomena originated in the magnetosphere, in the ionosphere and in the Earth-ionosphere cavity.

  18. Megapixel mercury cadmium telluride focal plane arrays for infrared imaging out to 12 microns, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose the fabrication of large format, long wave infrared (LWIR) mercury cadmium telluride (HgCdTe or MCT) detector arrays where the cutoff wavelength is...

  19. All-dielectric rod antenna array for terahertz communications

    Science.gov (United States)

    Withayachumnankul, Withawat; Yamada, Ryoumei; Fujita, Masayuki; Nagatsuma, Tadao

    2018-05-01

    The terahertz band holds a potential for point-to-point short-range wireless communications at sub-terabit speed. To realize this potential, supporting antennas must have a wide bandwidth to sustain high data rate and must have high gain and low dissipation to compensate for the free space path loss that scales quadratically with frequency. Here we propose an all-dielectric rod antenna array with high radiation efficiency, high gain, and wide bandwidth. The proposed array is integral to a low-loss photonic crystal waveguide platform, and intrinsic silicon is the only constituent material for both the antenna and the feed to maintain the simplicity, compactness, and efficiency. Effective medium theory plays a key role in the antenna performance and integrability. An experimental validation with continuous-wave terahertz electronic systems confirms the minimum gain of 20 dBi across 315-390 GHz. A demonstration shows that a pair of such identical rod array antennas can handle bit-error-free transmission at the speed up to 10 Gbit/s. Further development of this antenna will build critical components for future terahertz communication systems.

  20. An investigation of homogeneous and heterogeneous sonochemistry for the destruction of hazardous substances. Progress report, 1996 - 1997

    International Nuclear Information System (INIS)

    Hua, I.

    1997-01-01

    'The primary objective of this research project is to acquire a deeper fundamental knowledge of acoustic cavitation and cavitation chemistry, and in doing so, to ascertain how ultrasonic irradiation can be more effectively applied to environmental problems. Four on-going projects will be described in this progress report, The first project is the destruction of carbofuran in a Near-Field Acoustical Processor (NAP), and the hydrodynamic characterization of the reactor. The second project is a comprehensive study of how ultrasonic frequency influences sonochemical reaction rates; the substrate it, the preliminary portion of this study has been hydrogen peroxide formation. The third project in progress is destruction of four polychlorinated biphenyls at 20 kHz. Work so far has been at 20 kHz, but the most significant portion of this project will involve a multi-frequency (ultrasonic frequency) study. Finally, the destruction of a pesticide, dichlorvos, during sonication at 500 kHz will be described. Preliminary work during the first year has emphasized determination of kinetics; further work (years 2--3) will be focused upon closing mass balances and identifying transformation products.'

  1. Cantilever arrayed blood pressure sensor for arterial applanation tonometry.

    Science.gov (United States)

    Lee, Byeungleul; Jeong, Jinwoo; Kim, Jinseok; Kim, Bonghwan; Chun, Kukjin

    2014-03-01

    The authors developed a cantilever-arrayed blood pressure sensor array fabricated by (111) silicon bulk-micromachining for the non-invasive and continuous measurement of blood pressure. The blood pressure sensor measures the blood pressure based on the change in the resistance of the piezoresistor on a 5-microm-thick-arrayed perforated membrane and 20-microm-thick metal pads. The length and the width of the unit membrane are 210 and 310 microm, respectively. The width of the insensible zone between the adjacent units is only 10 microm. The resistance change over contact force was measured to verify the performance. The good linearity of the result confirmed that the polydimethylsiloxane package transfers the forces appropriately. The measured sensitivity was about 4.5%/N. The maximum measurement range and the resolution of the fabricated blood pressure sensor were greater than 900 mmHg (= 120 kPa) and less than 1 mmHg (= 133.3 Pa), respectively.

  2. Solar observations with the prototype of the Brazilian Decimetric Array

    Science.gov (United States)

    Sawant, H. S.; Ramesh, R.; Faria, C.; Cecatto, J. R.; Fernandes, F. C. R.; Madsen, F. H. R.; Subramanian, K. R.; Sundararajan, M. S.

    The prototype of the Brazilian Decimetric Array BDA consists of 5 element alt-az mounted parabolic mesh type dishes of 4-meter diameter having base lines up to 220 meters in the E--W direction The array was put into regular operation at Cachoeira Paulista Brazil longitude 45 r 00 20 W and latitude 22 r 41 19 S This array operates in the frequency range of 1 2 -- 1 7 GHz Solar observations are carried at sim 1 4 GHz in transit and tracking modes Spatial fine structures superimposed on the one dimensional brightness map of the sun associated with active regions and or with solar activity and their time evolution will be presented In the second phase of the project the frequency range will be increased to 1 2 - 1 7 2 8 and 5 6 GHz Central part of the array will consist of 26 antennas with 4-meter diameter laid out randomically in the square of 256 by 256 meter with minimum and maximum base lines of 8 and 256 meters respectively Details of this array with imaging capabilities in snap shot mode for solar observations and procedure of the phase and amplitude calibrations will be presented The development of instrument will be completed by the beginning of 2008

  3. 1024x1024 resistive emitter array design and fabrication status

    Science.gov (United States)

    Bryant, Paul T.; Oleson, Jim; McHugh, Stephen W.; Beuville, Eric; Schlesselmann, John D.; Woolaway, James T.; Barskey, Steve; Solomon, Steven L.; Joyner, Thomas W.

    2002-07-01

    Santa Barbara Infrared (SBIR) is producing a high performance 1,024 x 1,024 Large Format Resistive emitter Array (LFRA) for use in the next generation of IR Scene Projectors (IRSPs). LFRA requirements were developed through close cooperation with the Tri-Service IR Scene Projector working group, and through detailed trade studies sponsored by the OSD Central T&E Investment Program (CTEIP) and a Phase I US Navy Small Business Innovative Research (SBIR) contract. The CMOS Read-In Integrated Circuit (RIIC) is being designed by SBIR and Indigo Systems under a Small Business Innovative Research (SBIR) contract. Performance and features include 750 K MWIR maximum apparent temperature, 5 ms radiance rise time, 200 Hz full frame update, and 400 Hz window mode operation. Ten 8-inch CMOS wafers will be fabricated and characterized in mid-2002, followed by emitter fabrication in late 2002. This paper discusses array performance, requirements flow-down, array design, fabrication of 2 X 2-inch CMOS devices, and plans for subsequent RIIC wafer test and emitter pixel fabrication.

  4. Cyclotron-Resonance-Maser Arrays

    International Nuclear Information System (INIS)

    Kesar, A.; Lei, L.; Dikhtyar, V.; Korol, M.; Jerby, E.

    1999-01-01

    The cyclotron-resonance-maser (CRM) array [1] is a radiation source which consists of CRM elements coupled together under a common magnetic field. Each CRM-element employs a low-energy electron-beam which performs a cyclotron interaction with the local electromagnetic wave. These waves can be coupled together among the CRM elements, hence the interaction is coherently synchronized in the entire array. The implementation of the CRM-array approach may alleviate several technological difficulties which impede the development of single-beam gyro-devices. Furthermore, it proposes new features, such as the phased-array antenna incorporated in the CRM-array itself. The CRM-array studies may lead to the development of compact, high-power radiation sources operating at low-voltages. This paper introduces new conceptual schemes of CRM-arrays, and presents the progress in related theoretical and experimental studies in our laboratory. These include a multi-mode analysis of a CRM-array, and a first operation of this device with five carbon-fiber cathodes

  5. Optical Fiber Array Assemblies for Space Flight on the Lunar Reconnaissance Orbiter

    Science.gov (United States)

    Ott, Jelanie; Matuszeski, Adam

    2011-01-01

    Custom fiber optic bundle array assemblies developed by the Photonics Group at NASA Goddard Space Flight Center were an enabling technology for both the Lunar Orbiter Laser Altimeter (LOLA) and the Laser Ranging (LR) Investigation on the Lunar Reconnaissance Orbiter (LRO) currently in operation. The unique assembly array designs provided considerable decrease in size and weight and met stringent system level requirements. This is the first time optical fiber array bundle assemblies were used in a high performance space flight application. This innovation was achieved using customized Diamond Switzerland AVIM optical connectors. For LOLA, a five fiber array was developed for the receiver telescope to maintain precise alignment for each of the 200/220 micron optical fibers collecting 1,064 nm wavelength light being reflected back from the moon. The array splits to five separate detectors replacing the need for multiple telescopes. An image illustration of the LOLA instrument can be found at the top of the figure. For the laser ranging, a seven-optical-fiber array of 400/440 micron fibers was developed to transmit light from behind the LR receiver telescope located on the end of the high gain antenna system (HGAS). The bundle was routed across two moving gimbals, down the HGAS boom arm, over a deployable mandrel and across the spacecraft to a detector on the LOLA instrument. The routing of the optical fiber bundle and its end locations is identified in the figure. The Laser Ranging array and bundle is currently accepting light at a wavelength of 532 nm sent to the moon from laser stations at Greenbelt MD and other stations around the world to gather precision ranging information from the Earth to the LRO spacecraft. The LR bundle assembly is capable of withstanding temperatures down to -55 C at the connectors, and 20,000 mechanical gimbal cycles at temperatures as cold as -20 C along the length of the seven-fiber bundle (that is packaged into the gimbals). The total

  6. Degree-of-Freedom Strengthened Cascade Array for DOD-DOA Estimation in MIMO Array Systems.

    Science.gov (United States)

    Yao, Bobin; Dong, Zhi; Zhang, Weile; Wang, Wei; Wu, Qisheng

    2018-05-14

    In spatial spectrum estimation, difference co-array can provide extra degrees-of-freedom (DOFs) for promoting parameter identifiability and parameter estimation accuracy. For the sake of acquiring as more DOFs as possible with a given number of physical sensors, we herein design a novel sensor array geometry named cascade array. This structure is generated by systematically connecting a uniform linear array (ULA) and a non-uniform linear array, and can provide more DOFs than some exist array structures but less than the upper-bound indicated by minimum redundant array (MRA). We further apply this cascade array into multiple input multiple output (MIMO) array systems, and propose a novel joint direction of departure (DOD) and direction of arrival (DOA) estimation algorithm, which is based on a reduced-dimensional weighted subspace fitting technique. The algorithm is angle auto-paired and computationally efficient. Theoretical analysis and numerical simulations prove the advantages and effectiveness of the proposed array structure and the related algorithm.

  7. A Preliminary Formation Flying Orbit Dynamics Analysis for Leonardo-BRDF

    Science.gov (United States)

    Hughes, Steven P.; Mailhe, Laurie M.

    2001-01-01

    Leonardo-BRDF is a NASA mission concept proposed to allow the investigation of radiative transfer and its effect on the Earth's climate and atmospheric phenomenon. Enabled by the recent developments in small-satellite and formation flying technology, the mission is envisioned to be composed of an array of spacecraft in carefully designed orbits. The different perspectives provided by a distributed array of spacecraft offer a unique advantage to study the Earth's albedo. This paper presents the orbit dynamics analysis performed in the context of the Leonardo-BRDF science requirements. First, the albedo integral is investigated and the effect of viewing geometry on science return is studied. The method used in this paper, based on Gauss quadrature, provides the optimal formation geometry to ensure that the value of the integral is accurately approximated. An orbit design approach is presented to achieve specific relative orbit geometries while simultaneously satisfying orbit dynamics constraints to reduce formation-keeping fuel expenditure. The relative geometry afforded by the design is discussed in terms of mission requirements. An optimal two-burn initialization scheme is presented with the required delta-V to distribute all spacecraft from a common parking orbit into their appropriate orbits in the formation. Finally, formation-keeping strategies are developed and the associated delta-V's are calculated to maintain the formation in the presence of perturbations.

  8. Application of Schlumberger array of vertical electric sounding to ...

    African Journals Online (AJOL)

    The water bearing formations are probably sands, sandstones, gravels and or sands with clay intercalation. The resistivity values for the water bearing layers detected vary from 100 ohm-m to 20,000 ohm-m. Depths to probable water tables vary from 20m to 217m while the thicknesses of water bearing formations vary from ...

  9. Visualisation of air–water bubbly column flow using array Ultrasonic Velocity Profiler

    Directory of Open Access Journals (Sweden)

    Munkhbat Batsaikhan

    2017-11-01

    Full Text Available In the present work, an experimental study of bubbly two-phase flow in a rectangular bubble column was performed using two ultrasonic array sensors, which can measure the instantaneous velocity of gas bubbles on multiple measurement lines. After the sound pressure distribution of sensors had been evaluated with a needle hydrophone technique, the array sensors were applied to two-phase bubble column. To assess the accuracy of the measurement system with array sensors for one and two-dimensional velocity, a simultaneous measurement was performed with an optical measurement technique called particle image velocimetry (PIV. Experimental results showed that accuracy of the measurement system with array sensors is under 10% for one-dimensional velocity profile measurement compared with PIV technique. The accuracy of the system was estimated to be under 20% along the mean flow direction in the case of two-dimensional vector mapping.

  10. A review of array radars

    Science.gov (United States)

    Brookner, E.

    1981-10-01

    Achievements in the area of array radars are illustrated by such activities as the operational deployment of the large high-power, high-range-resolution Cobra Dane; the operational deployment of two all-solid-state high-power, large UHF Pave Paws radars; and the development of the SAM multifunction Patriot radar. This paper reviews the following topics: array radars steered in azimuth and elevation by phase shifting (phase-phase steered arrays); arrays steered + or - 60 deg, limited scan arrays, hemispherical coverage, and omnidirectional coverage arrays; array radars steering electronically in only one dimension, either by frequency or by phase steering; and array radar antennas which use no electronic scanning but instead use array antennas for achieving low antenna sidelobes.

  11. Anomalous enhancement in daytime 40-kHz signal amplitude accompanied by geomagnetic storms, earthquakes and meteor showers

    Directory of Open Access Journals (Sweden)

    B. K. De

    Full Text Available Anomalous propagational characteristics, daytime signal levels greater than night-time, were observed. The amplitude records of a 40-kHz signal propagated over a distance of 5100 km from Sanwa, Japan to Calcutta along a low-latitude path show higher signal strength at midday compared to the midnight level on days preceded by principal geomagnetic storms, earthquakes and major meteor showers. This is explained by the increased ionization in the D-region following geophysical events. The storm after-effects only have a duration of a single day in this low-latitude path.

  12. Anomalous enhancement in daytime 40-kHz signal amplitude accompanied by geomagnetic storms, earthquakes and meteor showers

    Directory of Open Access Journals (Sweden)

    B. K. De

    1995-10-01

    Full Text Available Anomalous propagational characteristics, daytime signal levels greater than night-time, were observed. The amplitude records of a 40-kHz signal propagated over a distance of 5100 km from Sanwa, Japan to Calcutta along a low-latitude path show higher signal strength at midday compared to the midnight level on days preceded by principal geomagnetic storms, earthquakes and major meteor showers. This is explained by the increased ionization in the D-region following geophysical events. The storm after-effects only have a duration of a single day in this low-latitude path.

  13. Direct observation of two-step crystallization in nanoparticle superlattice formation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jungwon; Zheng, Haimei; Lee, Won Chul; Geissler, Phillip L.; Rabani, Eran; Alivisatos, A. Paul

    2011-10-06

    Direct imaging of nanoparticle solutions by liquid phase transmission electron microscopy has enabled unique in-situ studies of nanoparticle motion and growth. In the present work, we report on real-time formation of two-dimensional nanoparticle arrays in the very low diffusive limit, where nanoparticles are mainly driven by capillary forces and solvent fluctuations. We find that superlattice formation appears to be segregated into multiple regimes. Initially, the solvent front drags the nanoparticles, condensing them into an amorphous agglomerate. Subsequently, the nanoparticle crystallization into an array is driven by local fluctuations. Following the crystallization event, superlattice growth can also occur via the addition of individual nanoparticles drawn from outlying regions by different solvent fronts. The dragging mechanism is consistent with simulations based on a coarse-grained lattice gas model at the same limit.

  14. Side-Chain Supramolecular Polymers Employing Conformer Independent Triple Hydrogen Bonding Arrays

    OpenAIRE

    Gooch, Adam; Murphy, Natasha S.; Thomson, Neil H.; Wilson, Andrew J.

    2013-01-01

    Derivatives of thymine have been extensively used to promote supramolecular materials assembly. Such derivatives can be synthetically challenging to access and may be susceptible to degradation. The current article uses a conformer-independent acceptor-donor-acceptor array (ureidopyrimidine) which forms moderate affinity interactions with diamidopyridine derivatives to effect supramolecular blend formation between polystyrene and poly(methyl methacrylate) polymers obtained by RAFT which have ...

  15. Neurodevelopmental disorders associated with dosage imbalance of ZBTB20 correlate with the morbidity spectrum of ZBTB20 candidate target genes

    DEFF Research Database (Denmark)

    Rasmussen, Malene B; Nielsen, Jakob V; Lourenço, Charles M

    2014-01-01

    (SRO) involved five RefSeq genes, including the transcription factor gene ZBTB20 and the dopamine receptor gene DRD3, considered as candidate genes for the syndrome. METHODS AND RESULTS: We used array comparative genomic hybridization and next-generation mate-pair sequencing to identify key structural...... patient with developmental delay and autism, we detected the first microdeletion at 3q13.31, which truncated ZBTB20 but did not involve DRD3 or the other genes within the previously defined SRO. Zbtb20 directly represses 346 genes in the developing murine brain. Of the 342 human orthologous ZBTB20...

  16. The EUROBALL array

    International Nuclear Information System (INIS)

    Rossi Alvarez, C.

    1998-01-01

    The quality of the multidetector array EUROBALL is described, with emphasis on the history and formal organization of the related European collaboration. The detector layout is presented together with the electronics and Data Acquisition capabilities. The status of the instrument, its performances and the main features of some recently developed ancillary detectors will also be described. The EUROBALL array is operational in Legnaro National Laboratory (Italy) since April 1997 and is expected to run up to November 1998. The array represents a significant improvement in detector efficiency and sensitivity with respect to the previous generation of multidetector arrays

  17. The standardized EEG electrode array of the IFCN.

    Science.gov (United States)

    Seeck, Margitta; Koessler, Laurent; Bast, Thomas; Leijten, Frans; Michel, Christoph; Baumgartner, Christoph; He, Bin; Beniczky, Sándor

    2017-10-01

    Standardized EEG electrode positions are essential for both clinical applications and research. The aim of this guideline is to update and expand the unifying nomenclature and standardized positioning for EEG scalp electrodes. Electrode positions were based on 20% and 10% of standardized measurements from anatomical landmarks on the skull. However, standard recordings do not cover the anterior and basal temporal lobes, which is the most frequent source of epileptogenic activity. Here, we propose a basic array of 25 electrodes including the inferior temporal chain, which should be used for all standard clinical recordings. The nomenclature in the basic array is consistent with the 10-10-system. High-density scalp EEG arrays (64-256 electrodes) allow source imaging with even sub-lobar precision. This supplementary exam should be requested whenever necessary, e.g. search for epileptogenic activity in negative standard EEG or for presurgical evaluation. In the near future, nomenclature for high density electrodes arrays beyond the 10-10 system needs to be defined, to allow comparison and standardized recordings across centers. Contrary to the established belief that smaller heads needs less electrodes, in young children at least as many electrodes as in adults should be applied due to smaller skull thickness and the risk of spatial aliasing. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  18. Applicability and safety of dual-frequency ultrasonic treatment for the transdermal delivery of drugs

    Science.gov (United States)

    Schoellhammer, Carl M.; Srinivasan, Sharanya; Barman, Ross; Mo, Stacy H.; Polat, Baris E.; Langer, Robert; Blankschtein, Daniel

    2016-01-01

    Low-frequency ultrasound presents an attractive method for transdermal drug delivery. The controlled, yet nonspecific nature of enhancement broadens the range of therapeutics that can be delivered, while minimizing necessary reformulation efforts for differing compounds. Long and inconsistent treatment times, however, have partially limited the attractiveness of this method. Building on recent advances made in this area, the simultaneous use of low- and high-frequency ultrasound is explored in a physiologically relevant experimental setup to enable the translation of this treatment to testing in vivo. Dual-frequency ultrasound, utilizing 20 kHz and 1 MHz wavelengths simultaneously, was found to significantly enhance the size of localized transport regions (LTRs) in both in vitro and in vivo models while decreasing the necessary treatment time compared to 20 kHz alone. Additionally, LTRs generated by treatment with 20 kHz + 1 MHz were found to be more permeable than those generated with 20 kHz alone. This was further corroborated with pore-size estimates utilizing hindered-transport theory, in which the pores in skin treated with 20 kHz + 1 MHz were calculated to be significantly larger than the pores in skin treated with 20 kHz alone. This demonstrates for the first time that LTRs generated with 20 kHz + 1 MHz are also more permeable than those generated with 20 kHz alone, which could broaden the range of therapeutics and doses administered transdermally. With regard to safety, treatment with 20 kHz + 1 MHz both in vitro and in vivo appeared to result in no greater skin disruption than that observed in skin treated with 20 kHz alone, an FDA-approved modality. This study demonstrates that dual-frequency ultrasound is more efficient and effective than single-frequency ultrasound and is well-tolerated in vivo. PMID:25662228

  19. Hybrid CMOS-Graphene Sensor Array for Subsecond Dopamine Detection.

    Science.gov (United States)

    Nasri, Bayan; Wu, Ting; Alharbi, Abdullah; You, Kae-Dyi; Gupta, Mayank; Sebastian, Sunit P; Kiani, Roozbeh; Shahrjerdi, Davood

    2017-12-01

    We introduce a hybrid CMOS-graphene sensor array for subsecond measurement of dopamine via fast-scan cyclic voltammetry (FSCV). The prototype chip has four independent CMOS readout channels, fabricated in a 65-nm process. Using planar multilayer graphene as biologically compatible sensing material enables integration of miniaturized sensing electrodes directly above the readout channels. Taking advantage of the chemical specificity of FSCV, we introduce a region of interest technique, which subtracts a large portion of the background current using a programmable low-noise constant current at about the redox potentials. We demonstrate the utility of this feature for enhancing the sensitivity by measuring the sensor response to a known dopamine concentration in vitro at three different scan rates. This strategy further allows us to significantly reduce the dynamic range requirements of the analog-to-digital converter (ADC) without compromising the measurement accuracy. We show that an integrating dual-slope ADC is adequate for digitizing the background-subtracted current. The ADC operates at a sampling frequency of 5-10 kHz and has an effective resolution of about 60 pA, which corresponds to a theoretical dopamine detection limit of about 6 nM. Our hybrid sensing platform offers an effective solution for implementing next-generation FSCV devices that can enable precise recording of dopamine signaling in vivo on a large scale.

  20. Structure and dye-sensitized solar cell application of TiO2 nanotube arrays fabricated by the anodic oxidation method

    Science.gov (United States)

    Ok, Seon-Yeong; Cho, Kwon-Koo; Kim, Ki-Won; Ryu, Kwang-Sun

    2010-05-01

    Well-ordered TiO2 nanotube arrays were fabricated by the potentiostatic anodic oxidation method using pure Ti foil as a working electrode and ethylene glycol solution as an electrolyte with the small addition of NH4F and H2O. The influence of anodization temperature and time on the morphology and formation of TiO2 nanotube arrays was examined. The TiO2 nanotube arrays were applied as a photoelectrode to dye-sensitized solar cells. Regardless of anodizing temperature and time, the average diameter and wall thickness of TiO2 nanotube arrays show a similar value, whereas the length increases with decreasing reaction temperature. The conversion efficiency is very low, which is due to a morphology breaking of the TiO2 nanotube arrays in the manufacturing process of a photoelectrode.