WorldWideScience

Sample records for array electrophoresis system

  1. An integrated multiple capillary array electrophoresis system for high-throughput DNA sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Lu, X.

    1998-03-27

    A capillary array electrophoresis system was chosen to perform DNA sequencing because of several advantages such as rapid heat dissipation, multiplexing capabilities, gel matrix filling simplicity, and the mature nature of the associated manufacturing technologies. There are two major concerns for the multiple capillary systems. One concern is inter-capillary cross-talk, and the other concern is excitation and detection efficiency. Cross-talk is eliminated through proper optical coupling, good focusing and immersing capillary array into index matching fluid. A side-entry excitation scheme with orthogonal detection was established for large capillary array. Two 100 capillary array formats were used for DNA sequencing. One format is cylindrical capillary with 150 {micro}m o.d., 75 {micro}m i.d and the other format is square capillary with 300 {micro}m out edge and 75 {micro}m inner edge. This project is focused on the development of excitation and detection of DNA as well as performing DNA sequencing. The DNA injection schemes are discussed for the cases of single and bundled capillaries. An individual sampling device was designed. The base-calling was performed for a capillary from the capillary array with the accuracy of 98%.

  2. Determination of Enantiomeric Excess of Glutamic Acids by Lab-made Capillary Array Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    Jun WANG; Kai Ying LIU; Li WANG; Ji Ling BAI

    2006-01-01

    Simulated enantiomeric excess of glutamic acid was determined by a lab-made sixteen-channel capillary array electrophoresis with confocal fluorescent rotary scanner. The experimental results indicated that the capillary array electrophoresis method can accurately determine the enantiomeric excess of glutamic acid and can be used for high-throughput screening system for combinatorial asymmetric catalysis.

  3. Design of a fraction collector for capillary array electrophoresis

    Czech Academy of Sciences Publication Activity Database

    Minarik, M.; Klepárník, Karel; Gilar, M.; Foret, František; Miller, A. W.; Sosic, Z.; Karger, B. L.

    2002-01-01

    Roč. 23, č. 1 (2002), s. 35-42. ISSN 0173-0835 R&D Projects: GA ČR GA203/00/0772 Institutional research plan: CEZ:AV0Z4031919 Keywords : fraction collector * capillary array electrophoresis * DNA analysis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.325, year: 2002

  4. Design and operation of a portable scanner for high performance microchip capillary array electrophoresis

    Science.gov (United States)

    Scherer, James R.; Liu, Peng; Mathies, Richard A.

    2010-11-01

    We have developed a compact, laser-induced fluorescence detection scanner, the multichannel capillary array electrophoresis portable scanner (McCAEPs) as a platform for electrophoretic detection and control of high-throughput, integrated microfluidic devices for genetic and other analyses. The instrument contains a confocal optical system with a rotary objective for detecting four different fluorescence signals, a pneumatic system consisting of two pressure/vacuum pumps and 28 individual addressable solenoid valves for control of on-chip microvalves and micropumps, four Polymerase Chain Reaction (PCR) temperature control systems, and four high voltage power supplies for electrophoresis. The detection limit of the instrument is ˜20 pM for on-chip capillary electrophoresis of fluorescein dyes. To demonstrate the system performance for forensic short tandem repeat (STR) analysis, two experiments were conducted: (i) electrophoretic separation and detection of STR samples on a 96-lane microfabricated capillary array electrophoresis microchip. Fully resolved PowerPlex® 16 STR profiles amplified from 1 ng of 9947A female standard DNA were successfully obtained; (ii) nine-plex STR amplification, sample injection, separation, and fluorescence detection of 100-copy 9948 male standard DNA in a single integrated PCR- capillary electrophoresis microchip. These results demonstrate that the McCAEPs can be used as a versatile control and detection instrument that operates integrated microfluidic devices for high-performance forensic human identification.

  5. Automatic Combination of Microfluidic Nanoliter-Scale Droplet Array with High-Speed Capillary Electrophoresis

    Science.gov (United States)

    Li, Q.; Zhu, Y.; Zhang, N.-Q.; Fang, Q.

    2016-05-01

    In this paper, we developed a novel approach for interfacing a microfluidic two-dimensional droplet array to a high-speed capillary electrophoresis (HSCE) system. Picoliter-scale sample injection (ca. 200 pL) from a nanoliter-scale droplet array covered by nonvolatile oil was automatically achieved using the spontaneous injection mode, without the interference from the cover oil and the need of special droplet extraction interface as in previously reported systems. The system was applied in consecutive separations of 25 different samples of amino acids with a whole separation time less than 15 min, as well as on-line monitoring of in-droplet derivatizing reaction of amino acids by fluorescein isothiocyanate (FITC) over 3 hours. High separation speed (up to 100 samples per hour) and high separation efficiency (up to 9.22 × 105 N/m) were achieved.

  6. Automatic Combination of Microfluidic Nanoliter-Scale Droplet Array with High-Speed Capillary Electrophoresis.

    Science.gov (United States)

    Li, Q; Zhu, Y; Zhang, N-Q; Fang, Q

    2016-01-01

    In this paper, we developed a novel approach for interfacing a microfluidic two-dimensional droplet array to a high-speed capillary electrophoresis (HSCE) system. Picoliter-scale sample injection (ca. 200 pL) from a nanoliter-scale droplet array covered by nonvolatile oil was automatically achieved using the spontaneous injection mode, without the interference from the cover oil and the need of special droplet extraction interface as in previously reported systems. The system was applied in consecutive separations of 25 different samples of amino acids with a whole separation time less than 15 min, as well as on-line monitoring of in-droplet derivatizing reaction of amino acids by fluorescein isothiocyanate (FITC) over 3 hours. High separation speed (up to 100 samples per hour) and high separation efficiency (up to 9.22 × 10(5) N/m) were achieved. PMID:27230468

  7. CMOS absorbance detection system for capillary electrophoresis

    International Nuclear Information System (INIS)

    This paper presents a cost-effective portable photodetection system for capillary electrophoresis absorptiometry. By using a CMOS BDJ (buried double p-n junction) detector, a dual-wavelength method for absorbance measurement is implemented. This system includes associated electronics for low-noise pre-amplification and A/D conversion, followed by digital signal acquisition and processing. Two signal processing approaches are adopted to enhance the signal to noise ratio. One is variable time synchronous detection, which optimizes the sensitivity and measuring rate compared to a conventional synchronous detection technique. The other is a statistical approach based on principal component analysis, which allows optimal estimation of detected signal. This system has been designed and tested in capillary electrophoresis conditions. Its operation has been verified with performances comparable to those of a commercialized spectrophotometric system (HP-3D CE). With potential on-chip integration of associated electronics, it may be operated as an integrable detection module for microchip electrophoresis and other microanalysis systems

  8. Microfluidic-based metal enhanced fluorescence for capillary electrophoresis by Ag nanorod arrays

    Science.gov (United States)

    Xiao, Chenyu; Cao, Zhen; Deng, Junhong; Huang, Zhifeng; Xu, Zheng; Fu, Junxue; Yobas, Levent

    2014-06-01

    As metal nanorods show much higher metal enhanced fluorescence (MEF) than metal nanospheres, microfluidic-based MEF is first explored with Ag nanorod (ND) arrays made by oblique angle deposition. By measuring the fluorescein isothiocyanate (FITC) solution sandwiched between the Ag NDs and a piece of cover slip, the enhancement factors (EFs) are found as 3.7 ± 0.64 and 6.74 ± 2.04, for a solution thickness at 20.8 μm and 10 μm, respectively. Because of the strong plasmonic coupling between the adjacent Ag NDs, only the emission of the fluorophores present in the three-dimensional NDs array gets enhanced. Thus, the corresponding effective enhancement factors (EEFs) are revealed to be relatively close, 259 ± 92 and 340 ± 102, respectively. To demonstrate the application of MEF in microfluidic systems, a multilayer of SiO2 NDs/Ag NDs is integrated with a capillary electrophoresis device. At a microchannel depth of 10 μm, an enhancement of 6.5 fold is obtained for amino acids separation detection. These results are very encouraging and open the possibility of MEF applications for the Ag ND arrays decorated microchannels. With the miniaturization of microfluidic devices, microfluidic-based MEF by Ag ND arrays will likely find more applications with further enhancement.

  9. Micro-size polyacrylamide gel electrophoresis system

    Science.gov (United States)

    Hinson, W. G.; Pipkin, J. L.; Anson, J. F.; Casciano, D. A.; Burns, E. R.

    1987-09-01

    The development and characterization of a micro-size two-dimensional polyacrylamide gel electrophoresis system is described. Some of the techniques which have evolved with use of the system are also discussed. This apparatus has unique features which provide advantages over other small scale units. Up to ten first- and second-dimension gels can be processed simultaneously with excellent resolution of protein regions. Consistent reproducibility is possible from protein samples as small as 400 ng and individual protein regions as small as 1 pg can be visualized by silver staining of the two-dimensional gels. Similar sensitivities are achieved in autoradiographs of 3H-labeled proteins extracted from the nuclei of cultured cells. The application of this system in conjunction with flow cytometric examination of nuclear DNA and electrostatic cell sorting of specific cell nuclei to provide homogeneous sample populations, allows subtle variations in isotope incorporation in proteins to be detected; whereas many times in generalized tissue samples these changes are masked. Also, these techniques elucidate the effects of external stimuli (chemicals, drugs, or environment) on protein synthesis and phosphorylation for analyses and comparison. Fabrication drawings are available upon request.

  10. Development of micropump-actuated negative pressure pinched injection for parallel electrophoresis on array microfluidic chip.

    Science.gov (United States)

    Li, Bowei; Jiang, Lei; Xie, Hua; Gao, Yan; Qin, Jianhua; Lin, Bingcheng

    2009-09-01

    A micropump-actuated negative pressure pinched injection method is developed for parallel electrophoresis on a multi-channel LIF detection system. The system has a home-made device that could individually control 16-port solenoid valves and a high-voltage power supply. The laser beam is excitated and distributes to the array separation channels for detection. The hybrid Glass-PDMS microfluidic chip comprises two common reservoirs, four separation channels coupled to their respective pneumatic micropumps and two reference channels. Due to use of pressure as a driving force, the proposed method has no sample bias effect for separation. There is only one high-voltage supply needed for separation without relying on the number of channels, which is significant for high-throughput analysis, and the time for sample loading is shortened to 1 s. In addition, the integrated micropumps can provide the versatile interface for coupling with other function units to satisfy the complicated demands. The performance is verified by separation of DNA marker and Hepatitis B virus DNA samples. And this method is also expected to show the potential throughput for the DNA analysis in the field of disease diagnosis. PMID:19681052

  11. Planetary In Situ Capillary Electrophoresis System (PISCES)

    Science.gov (United States)

    Willis, P. A.; Stockton, A. M.; Mora, M. F.; Cable, M. L.; Bramall, N. E.; Jensen, E. C.; Jiao, H.; Lynch, E.; Mathies, R. A.

    2012-10-01

    We propose to develop PISCES, a 3-kg, 2W, flight-capable microfluidic lab-on-a-chip capillary electrophoresis analyzer capable of ingesting solid, liquid, or gas samples and performing a suite of chemical analyses with parts per trillion sensitivity.

  12. Design and experimental verification of low-voltage two-dimensional CMOS electrophoresis platform with 32 × 32 sample/hold cell array

    Science.gov (United States)

    Yamaji, Yuuki; Niitsu, Kiichi; Nakazato, Kazuo

    2016-03-01

    Electrophoresis is widely used in biomedical applications. However, conventional (centimeter-order) electrophoresis requires a high-voltage power supply, which is not suitable for point-of-care testing (POCT). Electrophoresis is driven by electric fields, and miniaturization (from the centimeter order to the micrometer order) is effective for low-voltage operation. A CMOS platform is a cost-competitive and promising candidate for miniaturization and enables the integration of biomolecule manipulation by electrophoresis and its electrochemical sensing. These features will contribute to the development of a biochemical analyzer called the micro-total analysis system (µ-TAS). To realize a truly portable electrophoresis system, we present the design and experimental verification of a low-voltage (<1 V), two-dimensional CMOS electrophoresis platform with 32 × 32 sample/hold cell array. Experimental results showed successful constant voltage outputs to each electrode. By miniaturizing the electrode structure to a 60 µm pitch, we achieved sufficient electric field strength even at low voltages.

  13. Multichannel microchip electrophoresis device fabricated in polycarbonate with an integrated contact conductivity sensor array.

    Science.gov (United States)

    Shadpour, Hamed; Hupert, Mateusz L; Patterson, Donald; Liu, Changgeng; Galloway, Michelle; Stryjewski, Wieslaw; Goettert, Jost; Soper, Steven A

    2007-02-01

    A 16-channel microfluidic chip with an integrated contact conductivity sensor array is presented. The microfluidic network consisted of 16 separation channels that were hot-embossed into polycarbonate (PC) using a high-precision micromilled metal master. All channels were 40 microm deep and 60 microm wide with an effective separation length of 40 mm. A gold (Au) sensor array was lithographically patterned onto a PC cover plate and assembled to the fluidic chip via thermal bonding in such a way that a pair of Au microelectrodes (60 microm wide with a 5 microm spacing) was incorporated into each of the 16 channels and served as independent contact conductivity detectors. The spacing between the corresponding fluidic reservoirs for each separation channel was set to 9 mm, which allowed for loading samples and buffers to all 40 reservoirs situated on the microchip in only five pipetting steps using an 8-channel pipettor. A printed circuit board (PCB) with platinum (Pt) wires was used to distribute the electrophoresis high-voltage to all reservoirs situated on the fluidic chip. Another PCB was used for collecting the conductivity signals from the patterned Au microelectrodes. The device performance was evaluated using microchip capillary zone electrophoresis (mu-CZE) of amino acid, peptide, and protein mixtures as well as oligonucleotides that were separated via microchip capillary electrochromatography (mu-CEC). The separations were performed with an electric field (E) of 90 V/cm and were completed in less than 4 min in all cases. The conductivity detection was carried out using a bipolar pulse voltage waveform with a pulse amplitude of +/-0.6 V and a frequency of 6.0 kHz. The conductivity sensor array concentration limit of detection (SNR = 3) was determined to be 7.1 microM for alanine. The separation efficiency was found to be 6.4 x 10(4), 2.0 x 10(3), 4.8 x 10(3), and 3.4 x 10(2) plates for the mu-CEC of the oligonucleotides and mu-CZE of the amino acids, peptides

  14. Determination of dissociation constants of pharmacologically active xanthones by capillary zone electrophoresis with diode array detection.

    Science.gov (United States)

    Wu, Xiaomu; Gong, Suxuan; Bo, Tao; Liao, Yiping; Liu, Huwei

    2004-12-24

    In this article, the dissociation constants (pKa) of 10 pharmacologically active xanthones isolated from herbal medicine Securidaca inappendiculata were determined by capillary zone electrophoresis with diode array detection. The pKa values determined by the method based on the electrophoretic mobilities (calculated from migration times) have been proved by the method based on UV absorbance calculated from the online spectra corresponding peaks. No conspicuous difference was observed between the two methods with acceptable reproducibility. Two pKa values (pKa1 and pKa2) were found for four xanthones while generally the 10 compounds possess the pKa values ranging from 6.4 to 9.2. PMID:15641365

  15. Simultaneous determination of melamine and 5-hydroxymethylfurfural in milk by capillary electrophoresis with diode array detection.

    Science.gov (United States)

    Chen, Zhijun; Yan, Xiaomei

    2009-10-14

    This article describes the development of a simple analytical approach for the simultaneous determination of melamine and 5-hydroxymethylfurfural (HMF) in milk samples using capillary electrophoresis (CE) with diode array detection (DAD) for the first time. Ultraviolet absorption at wavelengths of 214 and 280 nm was applied for the detection of melamine and HMF, respectively. Milk samples were extracted with 1% trichloroacetic acid using a high-speed blender and ultrasonication. After centrifugation and filtration, the extract was analyzed by CE-DAD directly. Micellar electrokinetic capillary chromatography was employed as the separation mode by adding sodium dodecyl sulfate (SDS) to the electrolyte. Under optimal separation conditions, melamine, HMF, and interferents were well resolved. The linear dynamic ranges were 0.05-100 microg/mL for melamine (R(2) = 0.9996) and 0.1-100 microg/mL for HMF (R(2) = 0.9997). The assay detection limits were 0.047 microg/mL and 0.067 microg/mL for melamine and HMF, respectively. Satisfactory results were obtained for the assay recovery rate and repeatability. The proposed method was successfully applied for the analysis of melamine and HMF in real milk samples, and the results of melamine were comparable to those obtained using HPLC-UV reference method. PMID:19761188

  16. Biased reptation model with electroosmosis for DNA electrophoresis in microchannels with a sub-micron pillar array

    Science.gov (United States)

    Wang, Wentao; Chuen Chan, Yick; Lee, Yi-Kuen

    2011-08-01

    A novel biased reptation model with electroosmosis (BRE) is proposed for a long-chain DNA electrophoresis separation mechanism in microchannels with a sub-micron pillar array. The BRE model incorporates effective electroosmosis into the classical biased reptation model (BRM). Initial investigation of the BRM with additional electroosmosis flow was conducted. In order to validate the proposed BRE model, the apparent electrophoretic mobilities of different sizes of long-chain DNA, T4 DNA and lambda DNA at different electric fields were measured in a microfabricated electrophoresis chip with an embedded sub-micron pillar array. The current-monitoring method was used to measure the electroosmotic mobility in the microfabricated electrophoresis chip. The proposed BRE model shows much better agreement with the experimental results compared to the classical BRM and the semi-empirical results based on the biased reptation with fluctuation (BRF). The average standard error between our proposed BRE model and experimental data is 8.13% without any fitting parameters, while the errors are 343.01% for the BRM and 17.54% for the BRF with one fitting parameter, respectively.

  17. High-Throughput Analysis With 96-Capillary Array Electrophoresis and Integrated Sample Preparation for DNA Sequencing Based on Laser Induced Fluorescence Detection

    Energy Technology Data Exchange (ETDEWEB)

    Gang Xue

    2001-12-31

    The purpose of this research was to improve the fluorescence detection for the multiplexed capillary array electrophoresis, extend its use beyond the genomic analysis, and to develop an integrated micro-sample preparation system for high-throughput DNA sequencing. The authors first demonstrated multiplexed capillary zone electrophoresis (CZE) and micellar electrokinetic chromatography (MEKC) separations in a 96-capillary array system with laser-induced fluorescence detection. Migration times of four kinds of fluoresceins and six polyaromatic hydrocarbons (PAHs) are normalized to one of the capillaries using two internal standards. The relative standard deviations (RSD) after normalization are 0.6-1.4% for the fluoresceins and 0.1-1.5% for the PAHs. Quantitative calibration of the separations based on peak areas is also performed, again with substantial improvement over the raw data. This opens up the possibility of performing massively parallel separations for high-throughput chemical analysis for process monitoring, combinatorial synthesis, and clinical diagnosis. The authors further improved the fluorescence detection by step laser scanning. A computer-controlled galvanometer scanner is adapted for scanning a focused laser beam across a 96-capillary array for laser-induced fluorescence detection. The signal at a single photomultiplier tube is temporally sorted to distinguish among the capillaries. The limit of detection for fluorescein is 3 x 10{sup -11} M (S/N = 3) for 5-mW of total laser power scanned at 4 Hz. The observed cross-talk among capillaries is 0.2%. Advantages include the efficient utilization of light due to the high duty-cycle of step scan, good detection performance due to the reduction of stray light, ruggedness due to the small mass of the galvanometer mirror, low cost due to the simplicity of components, and flexibility due to the independent paths for excitation and emission.

  18. A CCD-based system for the detection of DNA in electrophoresis gels by UV absorption

    International Nuclear Information System (INIS)

    A method and apparatus for the detection and quantification of large fragments of unlabelled nucleic acids in agarose gels is presented. The technique is based on ultraviolet (UV) absorption by nucleotides. A deuterium source illuminates individual sample lanes of an electrophoresis gel via an array of optical fibres. As DNA bands pass through the illuminated region of the gel the amount of UV light transmitted is reduced because of absorption by the DNA. During electrophoresis the regions of DNA are detected on-line using a UV-sensitive charge coupled device (CCD). As the absorption coefficient is proportional to the mass of DNA the technique is inherently quantitative. The mass of DNA in a region of the gel is approximately proportional to the integrated signal in the corresponding section of the CCD image. This system currently has a detection limit of less than 1.25 ng compared with 2-10 ng for the most popular conventional technique, ethidium bromide (EtBr) staining. In addition the DNA sample remains in its native state. The removal of the carcinogenic dye from the detection procedure greatly reduces associated biological hazards. (author)

  19. System for loading slab-gel holders for electrophoresis separation

    Science.gov (United States)

    Anderson, Norman G.; Anderson, Norman L.

    1979-01-01

    A slab-gel loading system includes a prismatic chamber for filling a plurality of slab-gel holders simultaneously. Each slab-gel holder comprises a pair of spaced apart plates defining an intermediate volume for gel containment. The holders are vertically positioned in the chamber with their major surfaces parallel to the chamber end walls. A liquid inlet is provided at the corner between the bottom and a side wall of the chamber for distributing a polymerizable monomer solution or a coagulable colloidal solution into each of the holders. The chamber is rotatably supported so that filling can begin with the corner having the liquid inlet directed downwardly such that the solution is gently funneled upwardly, without mixing, along the diverging side and bottom surfaces. As filling proceeds, the chamber is gradually rotated to position the bottom wall in a horizontal mode. The liquid filling means includes a plastic envelope with a septum dividing it into two compartments for intermixing two solutions of different density and thereby providing a liquid flow having a density gradient. The resulting gels have a density gradient between opposite edges for subsequent use in electrophoresis separations.

  20. Electronic imaging systems for quantitative electrophoresis of DNA

    International Nuclear Information System (INIS)

    Gel electrophoresis is one of the most powerful and widely used methods for the separation of DNA. During the last decade, instruments have been developed that accurately quantitate in digital form the distribution of materials in a gel or on a blot prepared from a gel. In this paper, I review the various physical properties that can be used to quantitate the distribution of DNA on gels or blots and the instrumentation that has been developed to perform these tasks. The emphasis here is on DNA, but much of what is said also applies to RNA, proteins and other molecules. 36 refs

  1. A New Dual-electrode and Multi-channel Electrochemical DetectionSystem for Capillary Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    Bing Yi YANG; Jin Yuan MO; Rong LAI

    2004-01-01

    A new type of dual-electrode and multi-channel electrochemical detection technology for capillary electrophoresis is described in this paper. Two detectors(the amperometric detector and the conductometric detector)or two conductometric detectors are connected to the same capillary electrophoresis system. The whole system possesses the advantages of the two electrochemical detectors including sparing time,improving the analytical speed and expanding the sample range.The working electrode and detector cell are handled easily.The system was applied to sample detection with satisfactory results.

  2. Protein Electrophoresis/Immunofixation Electrophoresis

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Protein Electrophoresis Immunofixation Electrophoresis Share this page: Was this page helpful? Also known as: Serum Protein Electrophoresis; Protein ELP; SPE; SPEP; Urine Protein Electrophoresis; ...

  3. Acoustic array systems theory, implementation, and application

    CERN Document Server

    Bai, Mingsian R; Benesty, Jacob

    2013-01-01

    Presents a unified framework of far-field and near-field array techniques for noise source identification and sound field visualization, from theory to application. Acoustic Array Systems: Theory, Implementation, and Application provides an overview of microphone array technology with applications in noise source identification and sound field visualization. In the comprehensive treatment of microphone arrays, the topics covered include an introduction to the theory, far-field and near-field array signal processing algorithms, practical implementations, and common applic

  4. Conductivity detection for conventional and miniaturised capillary electrophoresis systems.

    Science.gov (United States)

    Guijt, Rosanne M; Evenhuis, Christopher J; Macka, Miroslav; Haddad, Paul R

    2004-12-01

    Since the introduction of capillary electrophoresis (CE), conductivity detection has been an attractive means of detection. No additional chemical properties are required for detection, and no loss in sensitivity is expected when miniaturising the detector to scale with narrow-bore capillaries or even to the microchip format. Integration of conductivity and CE, however, involves a challenging combination of engineering issues. In conductivity detection the resistance of the solution is most frequently measured in an alternating current (AC) circuit. The influence of capacitors both in series and in parallel with the solution resistance should be minimised during conductivity measurements. For contact conductivity measurements, the positioning and alignment of the detection electrodes is crucial. A contact conductivity detector for CE has been commercially available, but was withdrawn from the market. Microfabrication technology enables integration and precise alignment of electrodes, resulting in the popularity of conductivity detection in microfluidic devices. In contactless conductivity detection, the alignment of the electrodes with respect to the capillary is less crucial. Contactless conductivity detection (CCD) was introduced in capillary CE, and similar electronics have been applied for CCD using planar electrodes in microfluidic devices. A contactless conductivity detector for capillaries has been commercialised recently. In this review, different approaches towards conductivity detection in capillaries and chip-based CE are discussed. In contrast to previous reviews, the focus of the present review is on the technological developments and challenges in conductivity detection in CE. PMID:15597418

  5. On-Line Multichannel Raman Spectroscopic Detection System For Capillary Zone Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    An on-line multichannel Raman spectroscopic detection system for capillary electrophoresis was established by using an Ar+ laser and a cryogenically cooled ICCD. Resonant excitation Raman spectra of methyl red and methyl orange were employed to test the system. The result shows that it could yield on-line electrophoretogram and time series of Raman spectra.

  6. The selective fabrication of large-area highly ordered TiO2 nanorod and nanotube arrays on conductive transparent substrates via sol-gel electrophoresis

    International Nuclear Information System (INIS)

    Large-area free-standing arrays of TiO2 nanorods and nanotubes were selectively synthesized on transparent conducting indium tin oxide substrates using sol-gel electrophoresis and anodic alumina (AAO) thin film templates. The effect of sol-gel ageing on the growth of TiO2 was explained, providing a tailored ability to produce nanotubes and nanorods. An annular tungsten base electrode, stemming from the anodization of the AAO template, was found to be crucial to the growth of nanotubes. This was supported by a study of substrate annealing in a reducing atmosphere. The work can be readily adapted for the fabrication of free-standing arrays of other metal, metal oxide, and complex oxide nanorod and nanotube arrays on conducting substrates.

  7. Comparative analyses of amplicon migration behavior in differing denaturing gradient gel electrophoresis (DGGE) systems

    Science.gov (United States)

    Thornhill, D. J.; Kemp, D. W.; Sampayo, E. M.; Schmidt, G. W.

    2010-03-01

    Denaturing gradient gel electrophoresis (DGGE) is commonly utilized to identify and quantify microbial diversity, but the conditions required for different electrophoretic systems to yield equivalent results and optimal resolution have not been assessed. Herein, the influence of different DGGE system configuration parameters on microbial diversity estimates was tested using Symbiodinium, a group of marine eukaryotic microbes that are important constituents of coral reef ecosystems. To accomplish this, bacterial clone libraries were constructed and sequenced from cultured isolates of Symbiodinium for the ribosomal DNA internal transcribed spacer 2 (ITS2) region. From these, 15 clones were subjected to PCR with a GC clamped primer set for DGGE analyses. Migration behaviors of the resulting amplicons were analyzed using a range of conditions, including variation in the composition of the denaturing gradient, electrophoresis time, and applied voltage. All tests were conducted in parallel on two commercial DGGE systems, a C.B.S. Scientific DGGE-2001, and the Bio-Rad DCode system. In this context, identical nucleotide fragments exhibited differing migration behaviors depending on the model of apparatus utilized, with fragments denaturing at a lower gradient concentration and applied voltage on the Bio-Rad DCode system than on the C.B.S. Scientific DGGE-2001 system. Although equivalent PCR-DGGE profiles could be achieved with both brands of DGGE system, the composition of the denaturing gradient and application of electrophoresis time × voltage must be appropriately optimized to achieve congruent results across platforms.

  8. Light emitting diode, photodiode-based fluorescence detection system for DNA analysis with microchip electrophoresis.

    Science.gov (United States)

    Hall, Gordon H; Glerum, D Moira; Backhouse, Christopher J

    2016-02-01

    Electrophoretic separation of fluorescently end-labeled DNA after a PCR serves as a gold standard in genetic diagnostics. Because of their size and cost, instruments for this type of analysis have had limited market uptake, particularly for point-of-care applications. This might be changed through a higher level of system integration and lower instrument costs that can be realized through the use of LEDs for excitation and photodiodes for detection--if they provide sufficient sensitivity. Here, we demonstrate an optimized microchip electrophoresis instrument using polymeric fluidic chips with fluorescence detection of end-labeled DNA with a LOD of 0.15 nM of Alexa Fluor 532. This represents orders of magnitude improvement over previously reported instruments of this type. We demonstrate the system with an electrophoretic separation of two PCR products and their respective primers. We believe that this is the first LED-induced fluorescence microchip electrophoresis system with photodiode-based detection that could be used for standard applications of PCR and electrophoresis. PMID:26412502

  9. Iso-array rewriting P systems with context-free iso-array rules

    OpenAIRE

    Bhuvaneswari, K; Kalyani, T.; Thomas, D G; Nagar, A. K.; Thamburaj, R.

    2014-01-01

    A new computing model called P system is a highly distributed and parallel theoretical model, which is proposed in the area of membrane computing. Ceterchi et al. initially proposed array rewriting P systems by extending the notion of string rewriting P systems to arrays (2003). A theoretical model for picture generation using context-free iso-array grammar rules and puzzle iso-array grammar rules are introduced by Kalyani et al. (2004, 2006). Also iso-array rewriting P...

  10. The template preparation and characterization of three new shapes of titania nanometer-array systems

    Institute of Scientific and Technical Information of China (English)

    TIAN Yuming; XU Mingxia; LIU Xiangzhi; GE Lei

    2006-01-01

    A two-step anodization process was used to prepare highly ordered porous anodic alumina template (PAA). The template method was combined with the sol-electrophoresis deposition and sol-gel method to synthesize three types of nanometer-array systems. The titania nano-arrays have a high specific surface area. The sol-gel template method was also applied to prepare the rod-shaped titania nanowire-arrays. The diameter of titania nanometer-array is about 50 nm; the length is about 20 μm; and the distance of neighboring two nanowires is about 100 nm. Through controlling the pore depth of the template, the membrane with periodical modulating titania nanodots was prepared. The diameter of the nanodots on the membrane surface was about 75 nm and the dot distance was about 100 nm. Also a compact structure has been found on the back face of the membrane. The sol-electrophoresis template method was used to prepare the nanowire-array system with the shape of string of candied haws. The diameter of nanowires was about 75 nm and the length was about 20 μm. The periodic concave-convex structures were found in each nanowire and the shape looked like string of candied haws. The three types of nano-array systems have a high specific surface area. It can be predicted that this type of surface modulating array system will have new properties and effects that are different from those of common membranes, nanodots and nanowires.

  11. New electrolyte systems for capillary zone electrophoresis of metal cations and non-ionic organic compounds

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Y.

    1995-06-19

    Excellent separations of metal ions can be obtained very quickly by capillary electrophoresis provided a weak complexing reagent is incorporated into the electrolyte to alter the effective mobilities of the sample ions. Indirect photometric detection is possible by also adding a UV-sensitive ion to the electrolyte. Separations are described using phthalate, tartrate, lactate or hydroxyisobutyrate as the complexing reagent. A separation of twenty-seven metal ions was achieved in only 6 min using a lactate system. A mechanism for the separation of lanthanides is proposed for the hydroxyisobutyrate system.

  12. Serum proteins analysis by capillary electrophoresis

    OpenAIRE

    Uji, Yoshinori; Okabe, Hiroaki

    2001-01-01

    The purpose of this study was to evaluate the efficacy of multi-capillary electrophoresis instrument in clinical laboratory. An automated clinical capillary electrophoresis system was evaluated for performing serum proteins electrophoresis and immuno-fixation electrophoresis by subtraction. In this study the performance of capillary electrophoresis was compared with the cellulose acetate membrane electrophoresis and agarose gel immunofixation electrophoresis for serum proteins. The results of...

  13. Future sensor system needs for staring arrays

    Science.gov (United States)

    Miller, John Lester

    2011-05-01

    This is a systems application paper regarding how sensor systems may use future technology FPAs. A historical perspective is discussed along with lessons learned from previous technologies. Future system requirements for strained super-lattice (SLS), quantum dots (QDOT) and traditional quantum well infrared photo-diodes (QWIP) arrays will be presented from both a commercial and military perspective. New potential markets will open up in the future if certain FPA technologies can reduce cost and provide higher sensitivities at higher operating temperatures.

  14. Superresolution character of array confocal system

    Institute of Scientific and Technical Information of China (English)

    HUANG Xiang-dong; TAN Jiu-bin

    2006-01-01

    For the incomplete theory of the array confocal system,the more accurate theoretical model is built, and the new type of three-zone amplitude pupil filter is presented to improve the 3D detecting ability of the array confocal system.The 3D imaging equation based on Kirchhoff's diffraction theory in the paper is more accurate,compared with the exciting theory,and it can describe the system imaging process more exactly.Using the evaluation criterion of 3D superresolution,the parameter of the filter pupil is optimized.It can reduce the axial and transversal FWHM of every detecting channel.The results of computer simulation and experiment prove that the filter can improve the axial and transversal resolution at the same time,which can increase the 3D measure capability.

  15. Utilization of antenna arrays in HF systems.

    OpenAIRE

    Louis Bertel; Nasir M. Abbasi; Stuart M. Feeney; Sana Salous; Yvon Erhel; Hal J. Strangeways; E. Michael Warrington; Salil D. Gunashekar; Dominique Lemur; François Marie; Martial Oger

    2009-01-01

    Different applications of radio systems are based on the implementation of antenna arrays. Classically, radio direction

    finding operates with a multi channel receiving system connected to an array of receiving antennas. More

    recently, MIMO architectures have been propos...

  16. Sensor Arrays and Electronic Tongue Systems

    Directory of Open Access Journals (Sweden)

    Manel del Valle

    2012-01-01

    Full Text Available This paper describes recent work performed with electronic tongue systems utilizing electrochemical sensors. The electronic tongues concept is a new trend in sensors that uses arrays of sensors together with chemometric tools to unravel the complex information generated. Initial contributions and also the most used variant employ conventional ion selective electrodes, in which it is named potentiometric electronic tongue. The second important variant is the one that employs voltammetry for its operation. As chemometric processing tool, the use of artificial neural networks as the preferred data processing variant will be described. The use of the sensor arrays inserted in flow injection or sequential injection systems will exemplify attempts made to automate the operation of electronic tongues. Significant use of biosensors, mainly enzyme-based, to form what is already named bioelectronic tongue will be also presented. Application examples will be illustrated with selected study cases from the Sensors and Biosensors Group at the Autonomous University of Barcelona.

  17. Utilization of antenna arrays in HF systems

    Directory of Open Access Journals (Sweden)

    Louis Bertel

    2009-06-01

    Full Text Available

    Different applications of radio systems are based on the implementation of antenna arrays. Classically, radio direction

    finding operates with a multi channel receiving system connected to an array of receiving antennas. More

    recently, MIMO architectures have been proposed to increase the capacity of radio links by the use of antenna

    arrays at both the transmitter and receiver.

    The first part of this paper describes some novel experimental work carried out to examine the feasibility of applying

    MIMO techniques for communications within the HF radio band. A detailed correlation analysis of a variety

    of different antenna array configurations is presented. The second section of the paper also deals with HF

    MIMO communications, focusing on the problem from a modelling point of view. The third part presents a sensitivity

    analysis of different antenna array structures for HF direction finding applications. The results demonstrate

    that when modelling errors, heterogeneous antenna arrays are more robust in comparison to homogeneous structures


  18. The Australian Square Kilometre Array Pathfinder: System Architecture and Specifications of the Boolardy Engineering Test Array

    OpenAIRE

    Hotan, A. W.; Bunton, J. D.; Harvey-Smith, L.; Humphreys, B.; Jeffs, B. D.; Shimwell, T.; Tuthill, J.; Voronkov, M.; G. Allen; Amy, S.; Ardern, K.; Axtens, P.; Ball, L; Bannister, K.; Barker, S.

    2014-01-01

    This paper describes the system architecture of a newly constructed radio telescope - the Boolardy Engineering Test Array, which is a prototype of the Australian Square Kilometre Array Pathfinder telescope. Phased array feed technology is used to form multiple simultaneous beams per antenna, providing astronomers with unprecedented survey speed. The test array described here is a 6-antenna interferometer, fitted with prototype signal processing hardware capable of forming at least 9 dual-pola...

  19. Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides

    Science.gov (United States)

    Wang, Joseph; Escarpa, Alberto; Pumera, Martin; Feldman, Jason; Svehla, D. (Principal Investigator)

    2002-01-01

    A microfluidic analytical system for the separation and detection of organic peroxides, based on a microchip capillary electrophoresis device with an integrated amperometric detector, was developed. The new microsystem relies on the reductive detection of both organic acid peroxides and hydroperoxides at -700 mV (vs. Ag wire/AgCl). Factors influencing the separation and detection processes were examined and optimized. The integrated microsystem offers rapid measurements (within 130 s) of these organic-peroxide compounds, down to micromolar levels. A highly stable response for repetitive injections (RSD 0.35-3.12%; n = 12) reflects the negligible electrode passivation. Such a "lab-on-a-chip" device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring.

  20. Review on the development of truly portable and in-situ capillary electrophoresis systems

    Science.gov (United States)

    Lewis, A. P.; Cranny, A.; Harris, N. R.; Green, N. G.; Wharton, J. A.; Wood, R. J. K.; Stokes, K. R.

    2013-04-01

    Capillary electrophoresis (CE) is a technique which uses an electric field to separate a mixed sample into its constituents. Portable CE systems enable this powerful analysis technique to be used in the field. Many of the challenges for portable systems are similar to those of autonomous in-situ analysis and therefore portable systems may be considered a stepping stone towards autonomous in-situ analysis. CE is widely used for biological and chemical analysis and example applications include: water quality analysis; drug development and quality control; proteomics and DNA analysis; counter-terrorism (explosive material identification) and corrosion monitoring. The technique is often limited to laboratory use, since it requires large electric fields, sensitive detection systems and fluidic control systems. All of these place restrictions in terms of: size, weight, cost, choice of operating solutions, choice of fabrication materials, electrical power and lifetime. In this review we bring together and critique the work by researchers addressing these issues. We emphasize the importance of a holistic approach for portable and in-situ CE systems and discuss all the aspects of the design. We identify gaps in the literature which require attention for the realization of both truly portable and in-situ CE systems.

  1. Review on the development of truly portable and in-situ capillary electrophoresis systems

    International Nuclear Information System (INIS)

    Capillary electrophoresis (CE) is a technique which uses an electric field to separate a mixed sample into its constituents. Portable CE systems enable this powerful analysis technique to be used in the field. Many of the challenges for portable systems are similar to those of autonomous in-situ analysis and therefore portable systems may be considered a stepping stone towards autonomous in-situ analysis. CE is widely used for biological and chemical analysis and example applications include: water quality analysis; drug development and quality control; proteomics and DNA analysis; counter-terrorism (explosive material identification) and corrosion monitoring. The technique is often limited to laboratory use, since it requires large electric fields, sensitive detection systems and fluidic control systems. All of these place restrictions in terms of: size, weight, cost, choice of operating solutions, choice of fabrication materials, electrical power and lifetime. In this review we bring together and critique the work by researchers addressing these issues. We emphasize the importance of a holistic approach for portable and in-situ CE systems and discuss all the aspects of the design. We identify gaps in the literature which require attention for the realization of both truly portable and in-situ CE systems. (topical review)

  2. Convergent strand array liquid pumping system

    Science.gov (United States)

    Collins, Earl R., Jr. (Inventor)

    1989-01-01

    A surface-tension liquid pumping system is provided by one or more arrays of converging solid monofilament fibers or metal wires (strands) spaced apart at an input end to gather liquid, and gathered close together at the opposite end where menisci forms between wetted strands to force liquid in the direction of convergence of the strands. The liquid pumping system is independent of gravity. It is illustrated as being used in a heat pump having a heating box to vaporize the liquid and a condensing chamber. Condensed liquid is returned by the pumping system to the heating box where it is again vaporized. A vapor tube carries the vapor to the condensing chamber. In that way, a closed system pumps heat from the heating box to the evaporating chamber and from there radiated to the atmosphere.

  3. The Allen Telescope Array Commensal Observing System

    CERN Document Server

    Williams, Peter K G

    2012-01-01

    This memo describes the system used to conduct commensal correlator and beamformer observations at the Allen Telescope Array (ATA). This system was deployed for ~2 years until the ATA hibernation in 2011 and was responsible for collecting >5 TB of data during thousands of hours of observations. The general system design is presented and the implementation is discussed in detail. I emphasize the rationale for various design decisions and attempt to document a few aspects of ATA operations that might not be obvious to non-insiders. I close with some recommendations from my experience developing the software infrastructure and managing the correlator observations. These include: reuse existing systems; solve, don't avoid, tensions between projects, and share infrastructure; plan to make standalone observations to complement the commensal ones; and be considerate of observatory staff when deploying new and unusual observing modes. The structure of the software codebase is documented.

  4. Application of multiplicative array techniques for multibeam sounder systems

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.

    Multiplicative array processing is well known for its narrow beamwidth and low sidelobe level, but the array gain is quite low. The effectiveness of such a system becomes lower, especially when the signal to noise ratio is low. Proposed some...

  5. A parylene-based dual channel micro-electrophoresis system for rapid mutation detection via heteroduplex analysis

    NARCIS (Netherlands)

    Sukas, Sertan; Erson, Ayse Elif; Sert, Cuneyt; Kulah, Haluk

    2008-01-01

    A new dual channel micro-electrophoresis system for rapid mutation detection based on heteroduplex analysis was designed and implemented. Mutation detection was successfully achieved in a total separation length of 250 μm in less than 3 min for a 590 bp DNA sample harboring a 3 bp mutation causing a

  6. Low Cost Phased Array Antenna System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — JEM Engineering proved the technical feasibility of the FlexScan array?a very low-cost, highly-efficient, wideband phased array antenna?in Phase I, and stands ready...

  7. Microfluidic System for Solution Array Based Bioassays

    Energy Technology Data Exchange (ETDEWEB)

    Dougherty, G M; Tok, J B; Pannu, S S; Rose, K A

    2006-02-10

    The objective of this project is to demonstrate new enabling technology for multiplex biodetection systems that are flexible, miniaturizable, highly automated, low cost, and high performance. It builds on prior successes at LLNL with particle-based solution arrays, such as those used in the Autonomous Pathogen Detection System (APDS) successfully field deployed to multiple locations nationwide. We report the development of a multiplex solution array immunoassay based upon engineered metallic nanorod particles. Nanobarcodes{reg_sign} particles are fabricated by sequential electrodeposition of dissimilar metals within porous alumina templates, yielding optically encoded striping patterns that can be read using standard laboratory microscope optics and PC-based image processing software. The addition of self-assembled monolayer (SAM) coatings and target-specific antibodies allows each encoded class of nanorod particles to be directed against a different antigen target. A prototype assay panel directed against bacterial, viral, and soluble protein targets demonstrates simultaneous detection at sensitivities comparable to state of the art immunoassays, with minimal cross-reactivity. Studies have been performed to characterize the colloidal properties (zeta potential) of the suspended nanorod particles as a function of pH, the ionic strength of the suspending solution, and surface functionalization state. Additional studies have produced means for the non-contact manipulation of the particles, including the insertion of magnetic nickel stripes within the encoding pattern, and control via externally applied electromagnetic fields. Using the results of these studies, the novel Nanobarcodes{reg_sign} based assay was implemented in a prototype automated system with the sample processing functions and optical readout performed on a microfluidic card. The unique physical properties of the nanorod particles enable the development of integrated microfluidic systems for

  8. A simple and highly stable free-flow electrophoresis device with thermoelectric cooling system.

    Science.gov (United States)

    Yan, Jian; Guo, Cheng-Gang; Liu, Xiao-Ping; Kong, Fan-Zhi; Shen, Qiao-Yi; Yang, Cheng-Zhang; Li, Jun; Cao, Cheng-Xi; Jin, Xin-Qiao

    2013-12-20

    Complex assembly, inconvenient operations, poor control of Joule heating and leakage of solution are still fundamental issues greatly hindering application of free-flow electrophoresis (FFE) for preparative purpose in bio-separation. To address these issues, a novel FFE device was developed based on our previous work. Firstly, a new mechanical structure was designed for compact assembly of separation chamber, fast removal of air bubble, and good anti-leakage performance. Secondly, a highly efficient thermoelectric cooling system was used for dispersing Joule heating for the first time. The systemic experiments revealed the three merits: (i) 3min assembly without any liquid leakage, 80 times faster than pervious FFE device designed by us or commercial device (4h); (ii) 5s removing of air bubble in chamber, 1000-fold faster than a normal one (2h or more) and (iii) good control of Joule heating by the cooling system. These merits endowed the device high stable thermo- and hydro-dynamic flow for long-term separation even under high electric field of 63V/cm. Finally, the developed device was used for up to 8h continuous separation of 5mg/mL fuchsin acid and purification of three model proteins of phycocyanin, myoglobin and cytochrome C, demonstrating the applicability of FFE. The developed FFE device has evident significance to the studies on stem cell, cell or organelle proteomics, and protein complex as well as micro- or nano-particles. PMID:24246174

  9. High performance electrophoresis system for site-specific entrapment of nanoparticles in a nanoarray

    Science.gov (United States)

    Han, Jin-Hee; Lakshmana, Sudheendra; Kim, Hee-Joo; Hass, Elizabeth A.; Gee, Shirley; Hammock, Bruce D.; Kennedy, Ian

    2010-02-01

    A nanoarray, integrated with an electrophoretic system, was developed to trap nanoparticles into their corresponding nanowells. This nanoarray overcomes the complications of losing the function and activity of the protein binding to the surface in conventional microarrays by using minimum amounts of sample. The nanoarray is also superior to other biosensors that use immunoassays in terms of lowering the limit of detection to the femto- or atto-molar level. In addition, our electrophoretic particle entrapment system (EPES) is able to effectively trap the nanoparticles using a low trapping force for a short duration. Therefore, good conditions for biological samples conjugated with particles can be maintained. The channels were patterned onto a bi-layer consisting of a PMMA and LOL coating on conductive indium tin oxide (ITO)-coated glass slide by using e-beam lithography. The suspensions of 170 nm-nanoparticles then were added to the chip that was connected to a positive voltage. On top of the droplet, another ITO-coated-glass slide was covered and connected to a ground terminal. Negatively charged fluorescent nanoparticles (blue emission) were selectively trapped onto the ITO surface at the bottom of the wells by following electric field lines. Numerical modeling was performed by using commercially available software, COMSOL Multiphysics to provide better understanding about the phenomenon of electrophoresis in a nanoarray. Simulation results are also useful for optimally designing a nanoarray for practical applications.

  10. System qualification of Digital Detector Array (DDA)

    Energy Technology Data Exchange (ETDEWEB)

    Azeredo, Soraia R.; Oliveira, Davi F.; Nascimento, Joseilson R.; Lopes, Ricardo T., E-mail: soraia@lin.ufrj.br [Coordenacao dos Programas de Pos-Graducao em Engenharia (LIN/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Lab. de Instrumentacao Nuclear

    2013-07-01

    Digital Detector Arrays (DDAs) should be characterized to establish the operating conditions of the system prior to perform a NDT (Nondestructive Testing). The image quality in digital radiography depends on the exposure conditions and the properties of the digital detectors. Quantitative definitions of DDA characterization parameters are important to discussions about achieved image quality of a particular type of DDA and also contribute to quantitative comparison of DDAs so that an appropriate digital detector is selected to meet NDT requirements. Evaluations of DDA factors were performed as defined by the standard practice for manufacturing characterization of DDAs, ASTM E2597-07. The evaluations provided quantitative results of some characteristic parameters. The factors evaluated were: basic spatial resolution, achievable contrast sensitivity, specific material thickness range and image lag. The results of measurements of characterization parameters are presented and related with the definitions in ASTM E2597-07. (author)

  11. Phase discriminating capacitive array sensor system

    Science.gov (United States)

    Vranish, John M. (Inventor); Rahim, Wadi (Inventor)

    1993-01-01

    A phase discriminating capacitive sensor array system which provides multiple sensor elements which are maintained at a phase and amplitude based on a frequency reference provided by a single frequency stabilized oscillator. Sensor signals provided by the multiple sensor elements are controlled by multiple phase control units, which correspond to the multiple sensor elements, to adjust the sensor signals from the multiple sensor elements based on the frequency reference. The adjustment made to the sensor signals is indicated by output signals which indicate the proximity of the object. The output signals may also indicate the closing speed of the object based on the rate of change of the adjustment made, and the edges of the object based on a sudden decrease in the adjustment made.

  12. Advances in Automation and Throughput of the Mars Organic Analyzer Microchip Capillary Electrophoresis System

    Science.gov (United States)

    Haldeman, B. J.; Skelley, A. M.; Scherer, J. R.; Jayarajah, C.; Mathies, R. A.

    2005-12-01

    We have previously demonstrated the design, construction and testing of a portable microchip capillary electrophoresis (CE) instrument called the Mars Organic Analyzer (MOA) for analysis of amino acids and amine containing organic molecules (1). This instrument is designed to accept organic compounds isolated from samples by sublimation or by subcritical water extraction, to label the amine groups with fluorescamine, and to perform high resolution electrophoretic analysis. The CE instrument has shown remarkable robustness during successful field tests last year in the Panoche Valley, CA (1) and more recently in the Atacama Desert, Chile (2). For successful operation on Mars, however, it is necessary to operate autonomously and to analyze large numbers of samples, blanks, and standards. Toward this end we present here two advances in the MOA system that test key aspects of an eventual flight prototype. First, we have developed an automated microfluidic system and method for the autonomous loading, running and cleaning of the CE chip on the single channel MOA instrument. The integration of microfabricated PDMS valves and pumps with all-glass separation channels in a multilayer design enabled creation of structures for complex fluidic routing. Twenty sequential analyses of an amino acid standard were performed with an automated cleaning procedure between runs. In addition, dilutions were performed on-chip, and blanks were run to demonstrate the elimination of carry-over from run to run. These results demonstrate an important advance of the technology readiness level of the MOA. Second, we have designed, constructed and successfully tested a lab version of the multichannel instrument we initially proposed for the MSL opportunity. The portable Multi-Channel Mars Organic Analyzer (McMOA, 25 by 30 by 15 cm), was designed to sequentially interrogate eight radially oriented CE separation channels on a single wafer. Since each channel can be used to analyze 20 or more

  13. Digital image processing software system using an array processor

    International Nuclear Information System (INIS)

    A versatile array processor-based system for general-purpose image processing was developed. At the heart of this system is an extensive, flexible software package that incorporates the array processor for effective interactive image processing. The software system is described in detail, and its application to a diverse set of applications at LLNL is briefly discussed. 4 figures, 1 table

  14. Dumand-array data-acquisition system

    International Nuclear Information System (INIS)

    An overall data acquisition approach for DUMAND is described. The scheme assumes one array to shore optical fiber transmission line for each string of the array. The basic event sampling period is approx. 13 μsec. All potentially interesting data is transmitted to shore where the major processing is performed

  15. Capillary electrophoresis

    International Nuclear Information System (INIS)

    After a short historical introduction, the different modes of separation in capillary electrophoresis are explained and illustrated by practical examples. In addition, the most important parameters that can be used to optimize the selectivity of the separation, are discussed. (author) 27 refs.; 8 figs

  16. Eigenbeamforming array systems for sound source localization

    DEFF Research Database (Denmark)

    Tiana Roig, Elisabet

    D study aims at enhancing the performance of uniform circular ar- rays, and to a lesser extent, spherical arrays, for two- and three-dimensional localization problems, respectively. These array geometries allow to perform eigenbeamforming, beamforming based on the decomposition of the sound field in a...... spherical scatterer is recommended instead. A better visualization in the entire frequency range can be achieved with deconvo- lution methods, as they allow the recovery of the sound source distribution from a given beamformed map. Three efficient methods based on spectral procedures, originally conceived...... for planar-sparse arrays, are adapted to circular arrays. They rely on the fact that uniform circular arrays present an azimuthal response that is rather independent on the focusing direction. Finally, a method based on the combination of beamforming and acoustic holog- raphy is introduced for both...

  17. The Australian Square Kilometre Array Pathfinder: System Architecture and Specifications of the Boolardy Engineering Test Array

    CERN Document Server

    Hotan, A W; Harvey-Smith, L; Humphreys, B; Jeffs, B D; Shimwell, T; Tuthill, J; Voronkov, M; Allen, G; Amy, S; Ardern, K; Axtens, P; Ball, L; Bannister, K; Barker, S; Bateman, T; Beresford, R; Bock, D; Bolton, R; Bowen, M; Boyle, B; Braun, R; Broadhurst, S; Brodrick, D; Brooks, K; Brothers, M; Brown, A; Cantrall, C; Carrad, G; Chapman, J; Cheng, W; Chippendale, A; Chung, Y; Cooray, F; Cornwell, T; Davis, E; de Souza, L; DeBoer, D; Diamond, P; Edwards, P; Ekers, R; Feain, I; Ferris, D; Forsyth, R; Gough, R; Grancea, A; Gupta, N; Guzman, JC; Hampson, G; Haskins, C; Hay, S; Hayman, D; Hoyle, S; Jacka, C; Jackson, C; Jackson, S; Jeganathan, K; Johnston, S; Joseph, J; Kendall, R; Kesteven, M; Kiraly, D; Koribalski, B; Leach, M; Lenc, E; Lensson, E; Li, L; Mackay, S; Macleod, A; Maher, T; Marquarding, M; McClure-Griffiths, N; McConnell, D; Mickle, S; Mirtschin, P; Norris, R; Neuhold, S; Ng, A; O'Sullivan, J; Pathikulangara, J; Pearce, S; Phillips, C; Qiao, RY; Reynolds, J E; Rispler, A; Roberts, P; Roxby, D; Schinckel, A; Shaw, R; Shields, M; Storey, M; Sweetnam, T; Troup, E; Turner, B; Tzioumis, A; Westmeier, T; Whiting, M; Wilson, C; Wilson, T; Wormnes, K; Wu, X

    2014-01-01

    This paper describes the system architecture of a newly constructed radio telescope - the Boolardy Engineering Test Array, which is a prototype of the Australian Square Kilometre Array Pathfinder telescope. Phased array feed technology is used to form multiple simultaneous beams per antenna, providing astronomers with unprecedented survey speed. The test array described here is a 6-antenna interferometer, fitted with prototype signal processing hardware capable of forming at least 9 dual-polarisation beams simultaneously, allowing several square degrees to be imaged in a single pointed observation. The main purpose of the test array is to develop beamforming and wide-field calibration methods for use with the full telescope, but it will also be capable of limited early science demonstrations.

  18. Automated dual capillary electrophoresis system with hydrodynamic injection for the concurrent determination of cations and anions

    International Nuclear Information System (INIS)

    Highlights: • Concurrent determination of cations and anions was carried out by electrophoretic separation. • Optimized conditions for each class of analystes was possible by using separate capillaries. • Simultaneous hydrodynamic injection was carried out. • Pneumatic actuation was used for flushing and sample handling. • The denitrification of drinking water was successfully demonstrated. - Abstract: The capillary electrophoresis instrument developed for the concurrent determination of cations and anions features two separate capillaries and individual detectors to allow independent optimization for each group of ions. The capillaries are joined in a common injector block. The sample is drawn into the injector with a small membrane pump and automated simultaneous injection into both capillaries is achieved by pressurization of the fluid with compressed air. Flushing of the injector and of the capillaries with the background electrolyte is also carried out automatically by the same means. The buffer consisted of 12 mM histidine and 2 mM 18-crown-6 adjusted to pH 4 with acetic acid and was suitable for the contactless conductivity detection employed. The system was optimized for the determination of cationic NH4+ and anionic NO3− and NO2−, and linear calibration curves from about 20 μM up to about 1.5 mM were obtained for these ions. In a test run over 8 h, the reproducibility for the peak areas was within ±7%. For demonstration, the instrument was successfully applied to the concurrent monitoring of the concentrations of the three ions during the biological removal of ammonium from contaminated groundwater in a sequencing batch reactor, where NO3− and NO2− are formed as intermediate products

  19. Automated dual capillary electrophoresis system with hydrodynamic injection for the concurrent determination of cations and anions

    Energy Technology Data Exchange (ETDEWEB)

    Pham, Thi Thanh Thuy; Mai, Thanh Duc [University of Basel, Department of Chemistry, Spitalstrasse 51, Basel 4056 (Switzerland); Centre for Environmental Technology and Sustainable Development (CETASD), Hanoi University of Science, Nguyen Trai Street 334, Hanoi (Viet Nam); Nguyen, Thanh Dam [Centre for Environmental Technology and Sustainable Development (CETASD), Hanoi University of Science, Nguyen Trai Street 334, Hanoi (Viet Nam); Sáiz, Jorge [Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering – University of Alcalá, Ctra. Madrid-Barcelona km 33.6, Alcalá de Henares, Madrid 28871 (Spain); Pham, Hung Viet, E-mail: phamhungviet@hus.edu.vn [Centre for Environmental Technology and Sustainable Development (CETASD), Hanoi University of Science, Nguyen Trai Street 334, Hanoi (Viet Nam); Hauser, Peter C., E-mail: Peter.Hauser@unibas.ch [University of Basel, Department of Chemistry, Spitalstrasse 51, Basel 4056 (Switzerland)

    2014-09-02

    Highlights: • Concurrent determination of cations and anions was carried out by electrophoretic separation. • Optimized conditions for each class of analystes was possible by using separate capillaries. • Simultaneous hydrodynamic injection was carried out. • Pneumatic actuation was used for flushing and sample handling. • The denitrification of drinking water was successfully demonstrated. - Abstract: The capillary electrophoresis instrument developed for the concurrent determination of cations and anions features two separate capillaries and individual detectors to allow independent optimization for each group of ions. The capillaries are joined in a common injector block. The sample is drawn into the injector with a small membrane pump and automated simultaneous injection into both capillaries is achieved by pressurization of the fluid with compressed air. Flushing of the injector and of the capillaries with the background electrolyte is also carried out automatically by the same means. The buffer consisted of 12 mM histidine and 2 mM 18-crown-6 adjusted to pH 4 with acetic acid and was suitable for the contactless conductivity detection employed. The system was optimized for the determination of cationic NH{sub 4}{sup +} and anionic NO{sub 3}{sup −} and NO{sub 2}{sup −}, and linear calibration curves from about 20 μM up to about 1.5 mM were obtained for these ions. In a test run over 8 h, the reproducibility for the peak areas was within ±7%. For demonstration, the instrument was successfully applied to the concurrent monitoring of the concentrations of the three ions during the biological removal of ammonium from contaminated groundwater in a sequencing batch reactor, where NO{sub 3}{sup −} and NO{sub 2}{sup −} are formed as intermediate products.

  20. Low Cost Phased Array Antenna System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A program is proposed to research the applicability of a unique phased array technology, dubbed FlexScan, to S-band and Ku-band communications links between...

  1. The Submillimeter Wave Astronomy Satellite (SWAS) solar array system

    Science.gov (United States)

    Sneiderman, Gary

    1993-01-01

    The SWAS (Submillimeter Wave Astronomy Satellite) solar array system is described. It is an innovative approach to meet the missions requirements. The SWAS satellite provides a three axis stabilized platform to survey a variety of galactic cloud structures. This system includes highly reliable, lightweight launch latch, deployment, and lock mechanisms, and solar array panels that provide the maximum solar cell area. The design of the solar arrays are the result of system trades that included instrument and spacecraft thermal constraints, attitude control system maneuvering rates and pointing accuracies, the power system, and the spacecraft structure.

  2. Status and Plans for the Array Control and Data Acquisition System of the Cherenkov Telescope Array

    CERN Document Server

    Oya, I; Schwanke, U; Wegner, P; Balzer, A; Berge, D; Borkowski, J; Camprecios, J; Colonges, S; Colome, J; Champion, C; Conforti, V; Gianotti, F; Flour, T Le; Lindemann, R; Lyard, E; Mayer, M; Melkumyan, D; Punch, M; Tanci, C; Schmidt, T; Schwarz, J; Tosti, G; Verma, K; Weinstein, A; Wiesand, S; Wischnewski, R

    2015-01-01

    The Cherenkov Telescope Array (CTA) is the next-generation atmospheric Cherenkov gamma-ray observatory. CTA will consist of two installations, one in the northern, and the other in the southern hemisphere, containing tens of telescopes of different sizes. The CTA performance requirements and the inherent complexity associated with the operation, control and monitoring of such a large distributed multi-telescope array leads to new challenges in the field of the gamma-ray astronomy. The ACTL (array control and data acquisition) system will consist of the hardware and software that is necessary to control and monitor the CTA arrays, as well as to time-stamp, read-out, filter and store -at aggregated rates of few GB/s- the scientific data. The ACTL system must be flexible enough to permit the simultaneous automatic operation of multiple sub-arrays of telescopes with a minimum personnel effort on site. One of the challenges of the system is to provide a reliable integration of the control of a large and heterogene...

  3. Photovoltaic array mounting apparatus, systems, and methods

    Science.gov (United States)

    West, Jack Raymond; Atchley, Brian; Hudson, Tyrus Hawkes; Johansen, Emil

    2015-04-14

    A photovoltaic array, including: (a) supports laid out on a surface in rows and columns; (b) photovoltaic modules positioned on top of the supports; and (c) fasteners connecting the photovoltaic modules to the supports, wherein the supports have an upper pedestal surface and a lower pedestal surface such that the photovoltaic modules are positioned at a non-horizontal angle when edges of the photovoltaic modules are positioned on top of the upper and lower pedestal surfaces, and wherein a portion of the fasteners rotate to lock the photovoltaic modules onto the supports.

  4. Photovoltaic array mounting apparatus, systems, and methods

    Science.gov (United States)

    West, Jack Raymond; Atchley, Brian; Hudson, Tyrus Hawkes; Johansen, Emil

    2016-01-05

    A photovoltaic array, including: (a) supports laid out on a surface in rows and columns; (b) photovoltaic modules positioned on top of the supports; and (c) fasteners connecting the photovoltaic modules to the supports, wherein the supports have an upper pedestal surface and a lower pedestal surface such that the photovoltaic modules are positioned at a non-horizontal angle when edges of the photovoltaic modules are positioned on top of the upper and lower pedestal surfaces, and wherein a portion of the fasteners rotate to lock the photovoltaic modules onto the supports.

  5. Advanced reactor water cleanup system with high-temperature electrophoresis demineralization process as alternative to ion-exchange resin process

    International Nuclear Information System (INIS)

    The ion-exchange resin process has been widely applied to reactor water cleanup systems to remove impurities from the water used in boiling water reactors (BWRs). Toshiba has developed a high-temperature electrophoresis demineralization process as an alternative to the ion-exchange resin process for an advanced reactor water cleanup system. Since the new process uses only inorganic materials, high-temperature and high-pressure water can be fed directly to the system. The new system was confirmed to remove ions with high efficiency in a performance test using high-temperature and high-pressure water simulating BWR water. The advanced reactor water cleanup system will be greatly simplified because heat exchangers and resin-handling equipment are not required. It will also be economical due to reductions in heat loss and resin waste. (author)

  6. Performance of a sound card as data acquisition system and a lock-in emulated by software in capillary electrophoresis.

    Science.gov (United States)

    Mandaji, Marcos; Buckup, Tiago; Rech, Rafael; Correia, Ricardo Rego Bordalo; Kist, Tarso Ledur

    2007-03-30

    The performance of fluorescence detectors in capillary electrophoresis is maximized when the excitation light intensity is modulated in time with optimal frequencies. This is especially true when photomultiplier tubes are used to detect the fluorescent light. The photomultiplier tube amplified raw output signal can in principle be captured directly by a personal computer sound card (PCSC) and processed by a lock-in emulated by software. This possibility is demonstrated in the present work and the performance of this new setup is compared with a traditional data acquisition system. The results obtained with this "PCSC and lock-in emulated by software" were of the same quality or even better compared to that obtained by conventional time integrators (Boxcars) and data acquisition boards. With PCSC the limits of detection (LOD) found for both naphthalene-2,3-dicarboxaldehyde-derivatized tyrosine and alanine were 3.3 and 3.5fmol (injection of 5nL of samples at 0.66 and 0.70micromol/L), respectively. This is at least three times better compared to conventional systems when light emitting diodes (LEDs) are used as the excitation source in fluorescence detectors. The PCSC linear response range was also larger compared to conventional data acquisition boards. This scheme showed to be a practical and convenient alternative of data acquisition and signal processing for detection systems used in capillary electrophoresis. PMID:19071554

  7. A microelectromechanical system digital 3C array seismic cone penetrometer

    OpenAIRE

    Ghose, R.

    2012-01-01

    A digital 3C array seismic cone penetrometer has been developed for multidisciplinary geophysical and geotechnical applications. Seven digital triaxial microelectromechanical system accelerometers are installed at 0.25-m intervals to make a 1.5-m-long downhole seismic array. The accelerometers have a flat response up to 2 kHz. The seismic array is attached to a class 1 digital seismic cone, which measures cone tip resistance, sleeve friction, pore-pressure, and inclination. The downhole 3C ar...

  8. Attitude Determination System for a Phased Array Beamformer

    OpenAIRE

    Garrucho Moras, Lidia

    2015-01-01

    The project aims to design and build a control system for a new GNSS reflectometer. The instrument has two antenna arrays and it is needed to electronically steer the beams of these arrays (each array has two frequency bands and two beams per band) to point some satellites and the ground point where the transmitted signals from these satellites reflect. To achieve this, the instrument needs to determine the position and attitude of the sensor using GNSS receivers and IMUs and then it will cal...

  9. New multitarget constant modulus array for CDMA systems

    Institute of Scientific and Technical Information of China (English)

    Zhang Jidong; Zheng Baoyu

    2006-01-01

    A new multitarget constant modulus array is proposed for CDMA systems based on least squares constant modulus algorithm. The new algorithm is called pre-despreading decision directed least squares constant modulus algorithm (DDDLSCMA). In the new algorithm, the pre-despreading is first applied for multitarget arrays to remove some multiple access signals, then the despreaded signal is processed by the algorithm which united the constant modulus algorithm and decision directed method. Simulation results illustrate the good performance for the proposed algorithm.

  10. A Machine Vision System for Ball Grid Array Package Inspection

    Institute of Scientific and Technical Information of China (English)

    XIA Nian-jiong; CAO Qi-xin; LEE Jey

    2005-01-01

    An optical inspection method of the Ball Grid Array package (BGA) was proposed by using a machine vision system. The developed machine vision system could get main critical factors for BGA quality evaluation, such as the height of solder ball, diameter, pitch and coplanarity. The experiment has proved that this system is available for BGA failure detection.

  11. A data acquisition system for flat-panel imaging arrays

    International Nuclear Information System (INIS)

    An electronic data acquisition system for pixelated, two-dimensional, amorphous silicon x-ray imaging arrays has been developed. The system was designed in a modular fashion with digital control provided by field-programmable logic devices. This approach allows sections of the design to be upgraded with little impact on other aspects of the system. Good analog noise performance was obtained by matching the preamplifier design to the characteristics of the array outputs. The design of this system is presented and its performance quantified

  12. Non-denaturing gel electrophoresis system for the purification of membrane bound proteins

    International Nuclear Information System (INIS)

    A new method is described for the purification of a membrane bound glycoprotein, the kappa opioid receptor from human placental tissue. The method uses preparative slab-gel electrophoresis in the presence of the non-denaturing detergent CHAPS. A linear relationship between log molecular weight and SDS PAGE electrophoretic mobility of known molecular weight markers, in the presence of CHAPS, is observed. Using this method, we were able partially to purify an 3H-etorphine binding glycoprotein, from placental villus tissue, with an apparent molecular weight range of 60-70,000. The iodinated glycoprotein migrates in SDS PAGE with an apparent molecular weight of 63,000. This method may be useful for the isolation of membrane bound proteins, especially when an affinity ligand is not available

  13. Use of metal complexation in non-aqueous capillary electrophoresis systems for the separation and improved detection of tetracyclines.

    Science.gov (United States)

    Tjørnelund, J; Hansen, S H

    1997-08-29

    Metal complexation in non-aqueous capillary electrophoresis systems was evaluated for the separation and improved detection of tetracycline antibiotics using laser-induced fluorescence detection. It was found that three factors were important for the choice of complexing agent: (i) it should be soluble in the organic solvent used for the separation, (ii) it should have a sufficient fast complexing rate so as not to invalidate the electrophoretic separation and, (iii) it should give a large increase in the fluorescence intensity. Mg2+ ions were found to be the most suitable ions for the separation of the tetracyclines as the acetate salt of magnesium is very soluble in organic solvents and only a relatively low current was generated during electrophoresis making it possible to use high concentrations of the complexing metal ion. Metal complexation strongly intensified the fluorescence of tetracyclines and all organic solvents investigated further intensified the fluorescence, e.g. dimethylformamide improved the fluorescence of the oxytetracycline metal complex by a factor of 34 compared to water. However, magnesium acetate was not sufficiently soluble in dimethylformamide and therefore N-methylformamide, improving the fluorescence intensity by only a factor of 9, was used. It was demonstrated that the method can be used for the detection of tetracyclines at the ppb level in milk and plasma. PMID:9335125

  14. Phased-array antennas for future communication and sensor systems

    NARCIS (Netherlands)

    Vliet, F.E. van

    1998-01-01

    Traditionally, phased-array antenna systems have been exclusively used in radar systems. The development of these antennas has gained much momentum by the availability of integrated microwave components. Their flexibility and performance is reason to expect a much wider application in the coming yea

  15. A second level trigger system based on a microprocessor array

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, H.; Watase, Y. (National Laboratory for High Energy Physics, KEK, 1-1 Oho, Tsukuba, Ibaraki 305 (Japan)); Korhonen, T. (Department of High Energy Physics, Helsinki University, Siltavuorenpenger 20 D, 00170 Helsinki (Finland)); Taketani, A. (Department of Physics, Hiroshima University, Higashi-senda-machi, Naka-ku, Hiroshima 730 (Japan))

    1990-08-01

    A second level trigger system is being introduced to the KEK TRISTAN VENUS experiment. The system consists of a TRANSPUTER array of 2-dimensional lattice and several kinds of interfacing modulus. TRANSPUTER chips are mounted on these modules. Trigger data are all transferred using high speed serial links which connect the processors. The system is applied to the central drift chamber to perform track finding using its hit information. A data acquistion module attached to each FASTBUS crate gathers the hit wire pattern and transfers it to the processor array through its link. Track finding is performed in parallel form by sharing the data. The results is also transferred to a master FPI (FASTBUS Processor Interface) via a link. It takes less than 1 millisecond to distribute pattern data into the array and fast tracking less than 8 milliseconds was achieved.

  16. Application of capillary electrophoresis to the uranyl/citrate system in moderately acidic solutions

    International Nuclear Information System (INIS)

    The capillary electrophoresis method has been applied to the speciation study of uranium(VI) at room temperature, in 0.02M citrate buffer solutions, at pH values between 2.5 and 5.5 and at citrate/U ratios between 20 and 40. No negatively charged species have been pointed out at pH values lower than 3. For a pH value higher than 5, the electropherograms are ill-defined and the signals cannot be analyzed simply (owing to a high and rough baseline). In the pH range 3-5, up to 4 peaks can be attributed to U(VI) species. Two of them are likely due to the expected monomer [(UO2)(Cit)]- and dimer [(UO2)2(Cit)2]2- complex species and these species are shown to be in quasi-equilibrium with two other species possessing slightly lower migration velocities, [(UO2)H(Cit)(OH)]- and [(UO2)2H2(Cit)2(OH)2]2-, respectively. Speciation diagrams calculated by an exact analytical approach are proposed in order to explain the experimental results. A complete agreement between theoretical and experimental results needs to take into account kinetic and hydrolysis effects. (author)

  17. Fabrication and optical properties of TiO sub 2 nanowire arrays made by sol-gel electrophoresis deposition into anodic alumina membranes

    CERN Document Server

    Lin, Y; Yuan, X Y; Xie, T; Zhang, L D

    2003-01-01

    Ordered TiO sub 2 nanowire arrays have been successfully fabricated into the nanochannels of a porous anodic alumina membrane by sol-gel electrophoretic deposition. After annealing at 500 deg. C, the TiO sub 2 nanowire arrays and the individual nanowires were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), selected area electron diffraction (SAED) and x-ray diffraction (XRD). SEM and TEM images show that these nanowires are dense and continuous with a uniform diameter throughout their entire length. XRD and SAED analysis together indicate that these TiO sub 2 nanowires crystallize in the anatase polycrystalline structure. The optical absorption band edge of TiO sub 2 nanowire arrays exhibits a blue shift with respect of that of the bulk TiO sub 2 owing to the quantum size effect.

  18. Fabrication and optical properties of TiO2 nanowire arrays made by sol-gel electrophoresis deposition into anodic alumina membranes

    International Nuclear Information System (INIS)

    Ordered TiO2 nanowire arrays have been successfully fabricated into the nanochannels of a porous anodic alumina membrane by sol-gel electrophoretic deposition. After annealing at 500 deg. C, the TiO2 nanowire arrays and the individual nanowires were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), selected area electron diffraction (SAED) and x-ray diffraction (XRD). SEM and TEM images show that these nanowires are dense and continuous with a uniform diameter throughout their entire length. XRD and SAED analysis together indicate that these TiO2 nanowires crystallize in the anatase polycrystalline structure. The optical absorption band edge of TiO2 nanowire arrays exhibits a blue shift with respect of that of the bulk TiO2 owing to the quantum size effect

  19. Analysis of solar collector array systems using thermography

    Energy Technology Data Exchange (ETDEWEB)

    Eden, A.

    1980-01-01

    The use of thermography to analyze large solar collector array systems under dynamic operating conditions is discussed. The research has focused on thermographic techniques and equipment to determine temperature distributions, flow patterns, and air blockages in solar collectors. The results of this extensive study, covering many sites and types of collectors, illustrate the capabilities of infrared analysis as an analysis tool and operation and maintenance procedure when applied to large arrays. Thermographic analysis of most collector systems showed temperature distributions that indicated balanced flow patterns with both the thermographs and the hand-held unit. In three significant cases, blocked or broken collector arrays, which previously had gone undetected, were discovered. Using this analysis, validation studies of large computer codes could examine collector arrays for flow patterns or blockages that could cause disagreement between actual and predicted performance. Initial operation and balancing of large systems could be accomplished without complicated sensor systems not needed for normal operations. Maintenance personnel could quickly check their systems without climbing onto the roof and without complicated sensor systems.

  20. A Compact System of Capacitively Coupled Contactless Conductivity Detection Based on the Square Wave Excitation Signal for Capillary Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    Shui Feng ZHANG; Li Shi WANG; Zhi DANG

    2006-01-01

    This paper reported a compact system of capacitively coupled contactless conductivity detection (C4D) based on the square wave excitation voltage for capillary electrophoresis, and it exhibited excellent sensitivity at the optimal frequency of 198 kHz. The feasibility and sensitivity of this detector was demonstrated by simultaneous detection of thirteen ions including alkali,alkaline earth and heavy metal ions. And the detection limits (S/N 3) were in the range of 0.2-1μmol/L for Mn2+,K+,Na+,Mg2+,Ca2+ ,Li+ ,Ba2+ ,and 7-25μmol/L for Ni2+ ,Cu2+ ,Cd2+ ,Pb2+,Co2+ ,Zn2+.

  1. Code-modulated interferometric imaging system using phased arrays

    Science.gov (United States)

    Chauhan, Vikas; Greene, Kevin; Floyd, Brian

    2016-05-01

    Millimeter-wave (mm-wave) imaging provides compelling capabilities for security screening, navigation, and bio- medical applications. Traditional scanned or focal-plane mm-wave imagers are bulky and costly. In contrast, phased-array hardware developed for mass-market wireless communications and automotive radar promise to be extremely low cost. In this work, we present techniques which can allow low-cost phased-array receivers to be reconfigured or re-purposed as interferometric imagers, removing the need for custom hardware and thereby reducing cost. Since traditional phased arrays power combine incoming signals prior to digitization, orthogonal code-modulation is applied to each incoming signal using phase shifters within each front-end and two-bit codes. These code-modulated signals can then be combined and processed coherently through a shared hardware path. Once digitized, visibility functions can be recovered through squaring and code-demultiplexing operations. Pro- vided that codes are selected such that the product of two orthogonal codes is a third unique and orthogonal code, it is possible to demultiplex complex visibility functions directly. As such, the proposed system modulates incoming signals but demodulates desired correlations. In this work, we present the operation of the system, a validation of its operation using behavioral models of a traditional phased array, and a benchmarking of the code-modulated interferometer against traditional interferometer and focal-plane arrays.

  2. The Kepler DB, a Database Management System for Arrays, Sparse Arrays and Binary Data

    Science.gov (United States)

    McCauliff, Sean; Cote, Miles T.; Girouard, Forrest R.; Middour, Christopher; Klaus, Todd C.; Wohler, Bill

    2010-01-01

    The Kepler Science Operations Center stores pixel values on approximately six million pixels collected every 30-minutes, as well as data products that are generated as a result of running the Kepler science processing pipeline. The Kepler Database (Kepler DB) management system was created to act as the repository of this information. After one year of ight usage, Kepler DB is managing 3 TiB of data and is expected to grow to over 10 TiB over the course of the mission. Kepler DB is a non-relational, transactional database where data are represented as one dimensional arrays, sparse arrays or binary large objects. We will discuss Kepler DB's APIs, implementation, usage and deployment at the Kepler Science Operations Center.

  3. Biomedical applications of capillary electrophoresis

    Science.gov (United States)

    Kartsova, L. A.; Bessonova, E. A.

    2015-08-01

    The review deals with modern analytical approaches used in capillary electrophoresis for solving medical and biological problems: search for biomarkers of various diseases and rapid diagnosis based on characteristic profiles of biologically active compounds by capillary electrophoresis with mass spectrometric detection; monitoring of the residual drugs in biological fluids for evaluating the efficiency of drug therapy; testing of the enantiomeric purity of pharmaceutical products; the use of novel materials as components of stationary and pseudo-stationary phases in capillary electrophoresis and capillary electrochromatography to increase the selectivity of separation of components of complex matrices; and identification of various on-line preconcentration techniques to reduce the detection limits of biologically active analytes. A topical trend in capillary electrophoresis required in clinical practice, viz., the design of microfluidic systems, is discussed. The bibliography includes 173 references.

  4. Beam Switching Cylindrical Array Antenna System for Communication

    Directory of Open Access Journals (Sweden)

    V. C. Misra

    1998-10-01

    Full Text Available The beam switching cylindrical array, which is a unique system, has been designed and developed to cover 360° in azimuth plane by generating 16 beams with specified elevation coverage.In this design, the concept of fast aperture selection (4 x 4 in microseconds from the total cylindrical array has been realised successfully to meet the requirement of point-to-multipoint communication. The components of the array, viz., radiating elements, powder dividers, switches, etc., are designed in printed circuit type, and hence, objectives of lightweight and ease of reproducibility are achieved. The lightweight of the array makes it accessible for easy mounting at a specified height for achieving longer communication range. Finally, a low-loss radome is incorporated to protect the array from environmental conditions. The various parameters, viz., return loss, gain, and switched-beam radiation patterns were measured over a bandwidth of 300 MHz in L- band and typical measured results are presented in this paper.

  5. Application of high-resolution capillary array electrophoresis with automated fraction collection for GeneCalling analysis of the yeast genomic DNA

    Czech Academy of Sciences Publication Activity Database

    Berka, J.; Ruiz-Martinez, M. C.; Hammond, R.; Minarik, M.; Foret, František; Sosic, Z.; Klepárník, Karel; Karger, B. L.

    2003-01-01

    Roč. 24, č. 4 (2003), s. 639-647. ISSN 0173-0835 R&D Projects: GA ČR GA203/00/0772; GA ČR GA303/00/0928 Institutional research plan: CEZ:AV0Z4031919 Keywords : capillary array * fraction collection * gene expression profiling Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.040, year: 2003

  6. Investigation of six bioactive anthraquinones in slimming tea by accelerated solvent extraction and high performance capillary electrophoresis with diode-array detection.

    Science.gov (United States)

    Wang, Ning; Su, Ming; Liang, Shuxuan; Sun, Hanwen

    2016-05-15

    A rapid and effective method for effective separation and rapid simultaneous determination of six bioactive anthraquinones by capillary zone electrophoresis was developed. An accelerated solvent extraction procedure was used for the extraction of anthraquinones from slimming tea. Under the optimized conditions, the effective separation of six anthraquinones was achieved within 8 min. Good linearity was achieved, with a correlation coefficient (r) of ⩾ 0.999. The limit of detection ranged from 0.33 to 1.40 μg mL(-1). The intra- and inter-day relative standard deviation (RSD) of the six analytes was in the range of 2.3-3.9% and 3.2-4.9%, respectively. The average recovery of the six analytes from real tea samples was in the range of 86.15-98.30% with the RSD of 1.04-4.99%. The developed and validated method has speediness, high sensitivity, recovery and precision, and can be applied for the quality control of slimming tea. PMID:26775937

  7. A passive array antenna system for microwave imaging applications

    International Nuclear Information System (INIS)

    In this paper a 3-GHz imaging system based on a modulated scattering technique (MST) is described. By using a probe made of an array of (passive) dipoles rotating around a test area, it is possible to efficiently measure field-scattered data under approximately transverse-magnetic illumination conditions. In the paper, the functional description of system is provided together with some preliminary validation tests

  8. A nonlinear lumped model for ultrasound systems using CMUT arrays.

    Science.gov (United States)

    Satir, Sarp; Degertekin, F Levent

    2015-10-01

    We present a nonlinear lumped model that predicts the electrical input-output behavior of an ultrasonic system using CMUTs with arbitrary array/membrane/electrode geometry in different transmit-receive configurations and drive signals. The receive-only operation, where the electrical output signal of the CMUT array in response to incident pressure field is calculated, is included by modifying the boundary elementbased vibroacoustic formulation for a CMUT array in rigid baffle. Along with the accurate large signal transmit model, this formulation covers pitch-catch and pulse-echo operation when transmit and receive signals can be separated in time. In cases when this separation is not valid, such as CMUTs used in continuous wave transmit-receive mode, pulse-echo mode with a nearby hard or soft wall or in a bounded space such as in a microfluidic channel, an efficient formulation based on the method of images is used. Some of these particular applications and the overall modeling approach have been validated through comparison with finite element analysis on specific examples including CMUTs with multiple electrodes. To further demonstrate the capability of the model for imaging applications, the two-way response of a partial dual-ring intravascular ultrasound array is simulated using a parallel computing cluster, where the output currents of individual array elements are calculated for given input pulse and compared with experimental results. With its versatility, the presented model can be a useful tool for rapid iterative CMUT-based system design and simulation for a broad range of ultrasonic applications. PMID:26470049

  9. Developing infrared array controller with software real time operating system

    Science.gov (United States)

    Sako, Shigeyuki; Miyata, Takashi; Nakamura, Tomohiko; Motohara, Kentaro; Uchimoto, Yuka Katsuno; Onaka, Takashi; Kataza, Hirokazu

    2008-07-01

    Real-time capabilities are required for a controller of a large format array to reduce a dead-time attributed by readout and data transfer. The real-time processing has been achieved by dedicated processors including DSP, CPLD, and FPGA devices. However, the dedicated processors have problems with memory resources, inflexibility, and high cost. Meanwhile, a recent PC has sufficient resources of CPUs and memories to control the infrared array and to process a large amount of frame data in real-time. In this study, we have developed an infrared array controller with a software real-time operating system (RTOS) instead of the dedicated processors. A Linux PC equipped with a RTAI extension and a dual-core CPU is used as a main computer, and one of the CPU cores is allocated to the real-time processing. A digital I/O board with DMA functions is used for an I/O interface. The signal-processing cores are integrated in the OS kernel as a real-time driver module, which is composed of two virtual devices of the clock processor and the frame processor tasks. The array controller with the RTOS realizes complicated operations easily, flexibly, and at a low cost.

  10. VERITAS: Very energetic radiation imaging telescope array system

    International Nuclear Information System (INIS)

    The Very Energetic Radiation Imaging Telescope Array System (VERI-TAS) is a wide energy range (50 GeV-50 TeV) atmospheric Cherenkov detector and will start operation in 2004. The design is driven by a major scientific interest in jets of active galactic nuclei, probing the intergalactic IR fields with TeV γ-ray beams, measuring the high energy spectrum of γ-ray bursts and galactic sources of cosmic rays. Also γ-rays signatures of quantum gravity, neutralinos and primordial black holes constitute the exotic scientific motivations to built a highly versatile detector that can be operated in various modes. The technical concept and design of the seven-telescope array system is described

  11. Quantum Hall effect in bilayer system with array of antidots

    Science.gov (United States)

    Pagnossin, I. R.; Gusev, G. M.; Sotomayor, N. M.; Seabra, A. C.; Quivy, A. A.; Lamas, T. E.; Portal, J. C.

    2007-04-01

    We have studied the Quantum Hall effect in a bilayer system modulated by gate-controlled antidot lattice potential. The Hall resistance shows plateaus which are quantized to anomalous multiplies of h/e2. We suggest that this complex behavior is due to the nature of the edge-states in double quantum well (DQW) structures coupled to an array of antidots: these plateaus may be originated from the coexistence of normal and counter-rotating edge-states in different layers.

  12. Method and system for homogenizing diode laser pump arrays

    Energy Technology Data Exchange (ETDEWEB)

    Bayramian, Andrew James

    2016-05-03

    An optical amplifier system includes a diode pump array including a plurality of semiconductor diode laser bars disposed in an array configuration and characterized by a periodic distance between adjacent semiconductor diode laser bars. The periodic distance is measured in a first direction perpendicular to each of the plurality of semiconductor diode laser bars. The diode pump array provides a pump output propagating along an optical path and characterized by a first intensity profile measured as a function of the first direction and having a variation greater than 10%. The optical amplifier system also includes a diffractive optic disposed along the optical path. The diffractive optic includes a photo-thermo-refractive glass member. The optical amplifier system further includes an amplifier slab having an input face and position along the optical path and separated from the diffractive optic by a predetermined distance. A second intensity profile measured at the input face of the amplifier slab as a function of the first direction has a variation less than 10%.

  13. Method and system for homogenizing diode laser pump arrays

    Science.gov (United States)

    Bayramian, Andy J

    2013-10-01

    An optical amplifier system includes a diode pump array including a plurality of semiconductor diode laser bars disposed in an array configuration and characterized by a periodic distance between adjacent semiconductor diode laser bars. The periodic distance is measured in a first direction perpendicular to each of the plurality of semiconductor diode laser bars. The diode pump array provides a pump output propagating along an optical path and characterized by a first intensity profile measured as a function of the first direction and having a variation greater than 10%. The optical amplifier system also includes a diffractive optic disposed along the optical path. The diffractive optic includes a photo-thermo-refractive glass member. The optical amplifier system further includes an amplifier slab having an input face and position along the optical path and separated from the diffractive optic by a predetermined distance. A second intensity profile measured at the input face of the amplifier slab as a function of the first direction has a variation less than 10%.

  14. Development of a Fully Integrated Lab-on-a-Chip Electrophoresis System for ExoMars and Future Astrobiology Missions

    Science.gov (United States)

    Willis, P. A.; Fisher, A.; Greer, F.; Grunthaner, F. J.; Hoppe, D.; Chiesl, T.; Mathies, R. A.; Rolland, J. P.

    2009-04-01

    This paper will describe current and future development efforts in lab-on-a-chip instrumentation for astrobiological investigations underway at JPL. We will begin with a discussion of the current technology status of our autonomous microfluidic capillary electrophoresis (μCE) system integrated with on-chip perfluoropolyether (PFPE) membrane valves and pumps [1], as part of the Urey Instrument. This work builds on the μCE system developed by Skelley et al. [2], but extends the system capability through the use of bio- and spaceflight-compatible PFPE-membrane valves rather than utilizing a PDMS-based approach. The ultimate goal of this μCE system is to perform ultrasensitive compositional and chiral analysis of amino acids in order to determine if Mars harbors signatures of past or present life. An autonomously functioning flight version of this instrument will examine extracts from the Martian regolith as part of the Pasteur Payload of the 2016 ExoMars astrobiology mission. The four-layer wafer stack design utilizes independent CE channels patterned in glass, along with a PFPE membrane, a pneumatic manifold layer, and a fluidic bus layer. Three pneumatically driven on-chip diaphragm valves placed in series are used to peristaltically pump reagents, buffers, and samples to and from capillary electrophoresis electrode well positions. Electrophoretic separation occurs in the all-glass channels near the base of the structure. The valve geometries and layouts in our integrated two-channel PFPE system have been optimized for valve sealing characteristics and uniform device spacing across the wafer surface. This paper will discuss current experimental development work in our research group involving further integration of functionality into an autonomous multi-channel system with no human intervention, enabling CE analysis upon a dried sample after receipt of a single pre-programmed instruction set from the user. The key structure under current development is an

  15. Comparison of an Automated Repetitive-Sequence-Based PCR Microbial Typing System with Pulsed-Field Gel Electrophoresis for Molecular Typing of Vancomycin-Resistant Enterococcus faecium▿ †

    OpenAIRE

    Chuang, Yu-Chung; Wang, Jann-Tay; CHEN, MEI-LING; Chen, Yee-Chun

    2010-01-01

    Vancomycin-resistant Enterococcus faecium (VRE) has become an important health care-associated pathogen because of its rapid spread, limited therapeutic options, and possible transfer of vancomycin resistance to more-virulent pathogens. In this study, we compared the ability to detect clonal relationships among VRE isolates by an automated repetitive-sequence-based PCR (Rep-PCR) system (DiversiLab system) to pulsed-field gel electrophoresis (PFGE), the reference method for molecular typing of...

  16. Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow

    Directory of Open Access Journals (Sweden)

    Toda Tosifusa

    2006-10-01

    Full Text Available Abstract Background In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they are required to keep in formats suitable for subsequent data mining. Therefore, a well-developed open source laboratory information management system (LIMS should be available for their proteomics research studies. Results We developed an open source LIMS appropriately customized for 2-D gel electrophoresis-based proteomics workflow. The main features of its design are compactness, flexibility and connectivity to public databases. It supports the handling of data imported from mass spectrometry software and 2-D gel image analysis software. The LIMS is equipped with the same input interface for 2-D gel information as a clickable map on public 2DPAGE databases. The LIMS allows researchers to follow their own experimental procedures by reviewing the illustrations of 2-D gel maps and well layouts on the digestion plates and MS sample plates. Conclusion Our new open source LIMS is now available as a basic model for proteome informatics, and is accessible for further improvement. We hope that many research scientists working in the field of proteomics will evaluate our LIMS and suggest ways in which it can be improved.

  17. Restriction landmark cDNA scanning (RLCS): a novel cDNA display system using two-dimensional gel electrophoresis.

    Science.gov (United States)

    Suzuki, H; Yaoi, T; Kawai, J; Hara, A; Kuwajima, G; Wantanabe, S

    1996-01-01

    We have developed a new method, designated restriction landmark cDNA scanning (RLCS), which displays many cDNA species quantitatively and simultaneously as two-dimensional gel spots. In this method cDNA species of uniform length were prepared for each mRNA species using restriction enzymes. After the restriction enzyme sites were radiolabeled as landmarks, the labeled fragments were subjected to high resolution two-dimensional gel electrophoresis. In analyses of cDNA samples from adult mouse liver and brain (cerebral cortex, cerebellum and brain stem) we detected approximately 500 and >1000 discrete gel spots respectively of various intensities at a time. The spot patterns of the three brain regions were very similar, although not identical, but were quite different from the pattern for the liver. RNA blot hybridization analysis using several cloned spot DNAs as probes showed that differences in intensity of the spots among RLCS profiles correlated well with expression levels of the corresponding mRNA species in the brain regions. Because the spots and their intensities reflect distinct mRNA species and their expression level respectively, the RLCS is a novel cDNA display system which provides a great deal of information and should be useful for systematic documentation of differentially expressed genes. PMID:8628652

  18. A simple and compact fluorescence detection system for capillary electrophoresis and its application to food analysis.

    Science.gov (United States)

    Zhai, Haiyun; Yuan, Kaisong; Yu, Xiao; Chen, Zuanguang; Liu, Zhenping; Su, Zihao

    2015-10-01

    A novel fluorescence detection system for CE was described and evaluated. Two miniature laser pointers were used as the excitation source. A Y-style optical fiber was used to transmit the excitation light and a four-branch optical fiber was used to collect the fluorescence. The optical fiber and optical filter were imported into a photomultiplier tube without any extra fixing device. A simplified PDMS detection cell was designed with guide channels through which the optical fibers were easily aligned to the detection window of separation capillary. According to different requirements, laser pointers and different filters were selected by simple switching and replacement. The fluorescence from four different directions was collected at the same detecting point. Thus, the sensitivity was enhanced without peak broadening. The fluorescence detection system was simple, compact, low-cost, and highly sensitive, with its functionality demonstrated by the separation and determination of red dyes and fluorescent whitening agents. The detection limit of rhodamine 6G was 7.7 nM (S/N = 3). The system was further applied to determine illegal food dyes. The CE system is potentially eligible for food safety analysis. PMID:26109527

  19. The Detector Calibration System for the CUORE cryogenic bolometer array

    CERN Document Server

    Cushman, J S; Davis, C J; Ejzak, L; Lenz, D; Lim, K E; Heeger, K M; Maruyama, R H; Nucciotti, A; Sangiorgio, S; Wise, T

    2016-01-01

    The Cryogenic Underground Observatory for Rare Events (CUORE) is a ton-scale cryogenic experiment designed to search for neutrinoless double-beta decay of $^{130}$Te and other rare events. The CUORE detector consists of 988 TeO$_2$ bolometers operated underground at 10~mK in a dilution refrigerator at the Laboratori Nazionali del Gran Sasso. Candidate events are identified through a precise measurement of their energy. The absolute energy response of the detectors is established by the regular calibration of each individual bolometer using gamma sources. The close-packed configuration of the CUORE bolometer array combined with the extensive shielding surrounding the detectors requires the placement of calibration sources within the array itself. The CUORE Detector Calibration System is designed to insert radioactive sources into and remove them from the cryostat while respecting the stringent heat load, radiopurity, and operational requirements of the experiment. This paper describes the design, commissioning...

  20. Quantitative ultrasonic testing of pressure components using phased array systems

    International Nuclear Information System (INIS)

    For sufficiently accurate test results, ultrasonic testing must provide pictures of tomographic quality for the common test speeds and acceptable testing time and expenditure. This necessitates resconstruction of findings at all intromission angles if possible (-90 deg to +90 deg), high sensitivity and high resolution. Using phased array systems and reconstruction algorithms of ultrasonic migration and efficient, integer computer structures, ultrasonic pictures can be made at high speed from which the desired intromission angles and focusings can be calculated. This reconstruction technique makes it possible to deviate from the sampling theorem on which phased array techniques are based. Synthetic apertures can be produced which even at long sound transmission distances enable focusing with resolutions determined by the apertures of the individual elements. (orig.)

  1. Planar Microfluidic System Based on Electrophoresis for Detection of 130-nm Magnetic Labels for Biosensing

    Science.gov (United States)

    Takamura, Tsukasa; Morimoto, Yoshitaka; Sandhu, Adarsh

    2011-04-01

    Superparamagnetic beads (SPBs) used as magnetic labels offer potential for the realization of high sensitivity and low cost biosensors for point of care treatment (POCT). For better biomolecular affinity and higher sensitivity, it is desirable to use sub-200-nm-diameter SPBs comparable in size to actual biomolecules. However, the detection of small concentrations of such SPBs by magnetoresistive devices is extremely challenging due to small magnetic response of SPBs. As a solution to these limitations, we describe a simple detecting procedure where the capture of micro-SPBs by immobilized nano-target SPBs due to self-assembly induced by an external magnetic field, which was monitored under an optical microscope. Here we describe biosensing system based on self-assembly of micro-SPBs by nanoSPBs targets using a system without external pumps, thereby enabling greater miniaturization and portability.

  2. An interlaboratory comparison of ITS2-PCR for the identification of yeasts, using the ABI Prism 310 and CEQ8000 capillary electrophoresis systems

    Directory of Open Access Journals (Sweden)

    Verschraegen Gerda

    2005-03-01

    Full Text Available Abstract Background Currently, most laboratories identify yeasts routinely on the basis of morphology and biochemical reactivity. This approach has quite often limited discriminatory power and may require long incubation periods. Due to the increase of fungal infections and due to specific antifungal resistence patterns for different species, accurate and rapid identification has become more important. Several molecular techniques have been described for fast and reliable identification of yeast isolates, but interlaboratory exchangeability of identification schemes of molecular techniques has hardly been studied. Here, we compared amplified ITS2 fragment length determination by an ABI Prism 310 (Applied Biosystems, Foster City, Ca. capillary electrophoresis system with that obtained by a CEQ8000 (Beckman Coulter, Fullerton, Ca. capillary electrophoresis system. Results Although ITS2 size estimations on both systems differed and separate libraries had to be constructed for each system, both approaches had the same discriminatory power with regard to the 44 reference strains, identical identifications were obtained for 39/ 40 clinical isolates in both laboratories and strains from 51 samples were correctly identified using CEQ8000, when compared to phenotypic identification. Conclusion Identification of yeasts with ITS2-PCR followed by fragment analysis can be carried out on different capillary electrophoresis systems with comparable discriminatory power.

  3. PZT Network and Phased Array Lamb Wave Based SHM Systems

    International Nuclear Information System (INIS)

    With the application of newer materials, such as composite materials, and growing complexity and capacity of current aircraft structures, reliably and completely assess the condition of the total structures in real time is then of growing and utmost importance. PZT Network and Phased Array, Lamb wave based Structural Health Monitoring (SHM) systems were developed to be applied to thin panels. The selection of transducers, their size and selected locations for their installation are described. The development and selection of the signal generation and data acquisition systems is also presented in detail. The requirements conducing to the development and selection of these systems are laid and particularly the selection of the actuation signal applied is justified. The development of a damage detection algorithm based in the comparison of the current structural state to a reference state is described, to detect damage reflected Lamb waves. Such method was implemented in software and integrated in the SHM system developed. Subsequently the detection algorithm, based in discrete signals correlation, was further improved by incorporating statistical methods. For phased arrays, a novel damage location algorithm is presented based on the individual sensors response. A visualization method based concurrently in the statistical methods developed and superposition of the different results obtained from a test set was implemented. These tests conducted to the successful and repeatable detection of 1mm damages in a multiple damaged plate with great confidence. Finally, a brief comparison and a hybrid system implementation is presented.

  4. Quantification and speciation of technetium-99 in samples at low levels: contributions of capillary electrophoresis / ICP-MS system

    International Nuclear Information System (INIS)

    Given the low levels of 99Tc (long half-lived artificial radionuclide) in the environment (10-8 M to 10-12 M), its determination currently necessitates an enrichment and separation from the sample matrix prior to instrumental measurement. Therefore, nuclear safety monitoring requires the knowledge of the redox and chemical properties of this element in order to predict its behaviour and transfer in the environment. So, a separative and very sensitive measurement technique must thus be employed. We have developed a new environmental measurement method applied to the quantification and speciation of 99Tc in sample at environmental concentrations. Indeed, we have combined a Capillary Electrophoresis (CE) with an Inductively Coupled Plasma Mass Spectrometer (ICP-MS). The limit of detection of 99Tc is about 2.10-8 M by CE/ICP-MS system equipped with a PFA-50 nebuliser. In addition to the detection and measurement of technetium, we can separate online 99Tc(VII) of its interfering radionuclides like molybdenum and ruthenium by CE/ICP-MS. Indeed, due do the different migration time of each anions, it's possible to determinate a signal at m/z= 99 which is only given to 99Tc. Results obtained by this method have been compared to an usual radiochemical technique, extraction of Tc(VII) by a TEVA resin followed by ICP-MS measurement. Within the framework of storage of spent fuel, studies on the speciation of Tc(VII) by CE / ICP-MS iron-sulphide soils in anoxic conditions have shown that technetium VII is reduced by sulphured suspensions. (author)

  5. The ARCADE Raman Lidar System for the Cherenkov Telescope Array

    CERN Document Server

    Valore, Laura; Doro, Michele; Iarlori, Marco; Rizi, Vincenzo; Tonachini, Aurelio Siro; Vallania, Piero

    2015-01-01

    The Cherenkov Telescope Array (CTA) is the next generation of ground-based very high energy gamma-ray instruments; the facility will be organized in two arrays, one for each hemisphere. The atmospheric calibration of the CTA telescopes is a critical task. The atmosphere affects the measured Cherenkov yield in several ways: the air-shower development itself, the variation of the Cherenkov angle with altitude, the loss of photons due to scattering and absorption of Cherenkov light out of the camera field-of-view and the scattering of photons into the camera. In this scenario, aerosols are the most variable atmospheric component in time and space and therefore need a continuous monitoring. Lidars are among the most used instruments in atmospheric physics to measure the aerosol attenuation profiles of light. The ARCADE Lidar system is a very compact and portable Raman Lidar system that has been built within the FIRB 2010 grant and is currently taking data in Lamar, Colorado. The ARCADE Lidar is proposed to operat...

  6. Imaging MAMA detector systems. [Multi-Anode Microchannel Array

    Science.gov (United States)

    Slater, David C.; Timothy, J. G.; Morgan, Jeffrey S.; Kasle, David B.

    1990-01-01

    Imaging multianode microchannel array (MAMA) detector systems with 1024 x 1024 pixel formats have been produced for visible and UV wavelengths; the UV types employ 'solar blind' photocathodes whose detective quantum efficiencies are significantly higher than those of currently available CCDs operating at far-UV and EUV wavelengths. Attention is presently given to the configurations and performance capabilities of state-of-the-art MAMA detectors, with a view to the development requirements of the hybrid electronic circuits needed for forthcoming spacecraft-sensor applications. Gain, dark noise, uniformity, and dynamic range performance data are presented for the curved-channel 'chevron', 'Z-plate', and helical-channel high gain microchannel plate configurations that are currently under evaluation with MAMA detector systems.

  7. High-voltage and gel electrophoresis for the determination of radionuclidic impurities in fission molybdenum (Mo-99) including data processing, documentation- and information system

    International Nuclear Information System (INIS)

    The purpose of this work was to find a better method for the determination of radionuclidic impurities in fission molybdenum using high voltage - and gel electrophoresis. Using Whatman chromatography paper could be achieved good results under following conditions: voltage 20 V/cm, electric current 2 mA, electrolyte 0.1 M α-hydroxyisobutiric acid and separation time 30 minutes. Under these conditions, Ru-103 and Br-82 could be separated in 30 minutes. I-131 could be separated also but its separation using the distillation method showed better results. The separation of Ba-140 and La-140 needed 45 minutes. A gel electrophoresis vessel has been designed for the experiment using gel electrophoresis. The experiments have been carried out under following conditions: voltage 30 V/cm, electric current 5 mA, anode electrolyte 0.1 N HCl, cathode electrolyte 0.05 M (NH4)2H-citrate and separation time 4 hours. Under these conditions, Ru-103, Br-82 and I-131 could be separated but Ba-140 and La-140 could not be separated. Two computer programs have been made in this work namely 'Program for Radiochromatography Scanner' and 'Radionuclidic Impurities Determination of Fission Molybdenum'. Microsoft visual basic for MS-DOS and Windows have been used for making these computer programs. These computer programs were very useful for further experiments and they contain data processing, documentation- and information system. (author)

  8. Use of capillary electrophoresis as a method development tool for classical gel electrophoresis

    OpenAIRE

    Sutton, Richard M. C.; Gratz, Samuel R.; Stalcup, Apryll M.

    1998-01-01

    Capillary electrophoresis (CE) was used to optimize the buffer pH, ionic strength and sulfated cyclodextrin concentrations for enantiomeric separation of piperoxan. These enantioseparation conditions were then applied to a classical gel electrophoresis system. Binding constants of the sulfated beta-cyclodextrin–piperoxan couple were approximated using CE and the effects of organic solvents on the system were also investigated.

  9. MEMS Microshutter Array System for James Webb Space Telescope

    Science.gov (United States)

    Li, Mary J.; Adachi, Tomoko; Allen, Christine; Babu, Sachi; Bajikar, Sateesh; Beamesderfer, Michael; Bradley, Ruth; Denis, Kevin; Costen, Nick; Ewin, Audrey; Franz, Dave; Hess, Larry; Hu, Ron; Jackson, Kamili; Jhabvala, Murzy; Kelly, Dan; King, Todd; Kletetschka, Gunther; Kutyrev, Alexander; Lynch, Barney; Miller, Timothy; Moseley, Harvey; Mikula, Vilem; Mott. Brent; Oh, Lance

    2008-01-01

    A complex MEMS microshutter array system has been developed at NASA Goddard Space Flight Center (GSFC) for use as a multi-object aperture array for a Near-Infrared Spectrometer (NIRSpec). The NIRSpec is one of the four major instruments carried by the James Webb Space Telescope (JWST), the next generation of space telescope after the Hubble Space Telescope retires. The microshutter arrays (MSAs) are designed for the selective transmission of light with high efficiency and high contrast. It is demonstrated in Figure 1 how a MSA is used as a multiple object selector in deep space. The MSAs empower the NIRSpec instrument simultaneously collect spectra from more than 100 targets therefore increases the instrument efficiency 100 times or more. The MSA assembly is one of three major innovations on JWST and the first major MEMS devices serving observation missions in space. The MSA system developed at NASA GSFC is assembled with four quadrant fully addressable 365x171 shutter arrays that are actuated magnetically, latched and addressed electrostatically. As shown in Figure 2, each MSA is fabricated out of a 4' silicon-on-insulator (SOI) wafer using MEMS bulk-micromachining technology. Individual shutters are close-packed silicon nitride membranes with a pixel size close to 100x200 pm (Figure 3). Shutters are patterned with a torsion flexure permitting shutters to open 90 degrees with a minimized mechanical stress concentration. In order to prevent light leak, light shields are made on to the surrounding frame of each shutter to cover the gaps between the shutters and the Game (Figure 4). Micro-ribs and sub-micron bumps are tailored on hack walls and light shields, respectively, to prevent sticktion, shown in Figures 4 and 5. JWST instruments are required to operate at cryogenic temperatures as low as 35K, though they are to be subjected to various levels of ground tests at room temperature. The shutters should therefore maintain nearly flat in the entire temperature range

  10. A Capillary Electrophoresis Detection Scheme for Water-soluble Vitamins Based on Luminol - BrO- Chemiluminescence System

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A novel chemiluminescence detection scheme has been developed for detecting water-soluble vitamins following capillary electrophoresis (CE) separation. This detection was based on the inhibitory effect of vitamins on the CL reaction between luminol and BrO- in basic aqueous solution. Detection of vitamins was accomplished with a borate-based background electrolyte at pH 9.2. The luminol was used as a component of the separation carrier electrolyte.

  11. Electronic system for high power load control. [solar arrays

    Science.gov (United States)

    Miller, E. L. (Inventor)

    1980-01-01

    Parallel current paths are divided into two groups, with control devices in the current paths of one group each having a current limiting resistor, and the control devices in the other group each having no limiting resistor, so that when the control devices of the second group are turned fully on, a short circuit is achieved by the arrangement of parallel current paths. Separate but coordinated control signals are provided to turn on the control devices of the first group and increase their conduction toward saturation as a function of control input, and when fully on, or shortly before, to turn on the control devices of the second group and increase their conduction toward saturation as a function of the control input as that input continues to increase. Electronic means may be used to generate signals. The system may be used for 1-V characteristic measurements of solar arrays as well as for other load control purposes.

  12. The Digital Motion Control System for the Submillimeter Array Antennas

    Science.gov (United States)

    Hunter, T. R.; Wilson, R. W.; Kimberk, R.; Leiker, P. S.; Patel, N. A.; Blundell, R.; Christensen, R. D.; Diven, A. R.; Maute, J.; Plante, R. J.; Riddle, P.; Young, K. H.

    2013-09-01

    We describe the design and performance of the digital servo and motion control system for the 6-meter parabolic antennas of the Submillimeter Array (SMA) on Mauna Kea, Hawaii. The system is divided into three nested layers operating at a different, appropriate bandwidth. (1) A rack-mounted, real-time Unix system runs the position loop which reads the high resolution azimuth and elevation encoders and sends velocity and acceleration commands at 100 Hz to a custom-designed servo control board (SCB). (2) The microcontroller-based SCB reads the motor axis tachometers and implements the velocity loop by sending torque commands to the motor amplifiers at 558 Hz. (3) The motor amplifiers implement the torque loop by monitoring and sending current to the three-phase brushless drive motors at 20 kHz. The velocity loop uses a traditional proportional-integral-derivative (PID) control algorithm, while the position loop uses only a proportional term and implements a command shaper based on the Gauss error function. Calibration factors and software filters are applied to the tachometer feedback prior to the application of the servo gains in the torque computations. All of these parameters are remotely adjustable in the software. The three layers of the control system monitor each other and are capable of shutting down the system safely if a failure or anomaly occurs. The Unix system continuously relays the antenna status to the central observatory computer via reflective memory. In each antenna, a Palm Vx hand controller displays the complete system status and allows full local control of the drives in an intuitive touchscreen user interface. The hand controller can also be connected outside the cabin, a major convenience during the frequent reconfigurations of the interferometer. Excellent tracking performance ( 0.3‧‧ rms) is achieved with this system. It has been in reliable operation on 8 antennas for over 10 years and has required minimal maintenance.

  13. LLNL current meter array--concept and system description

    Energy Technology Data Exchange (ETDEWEB)

    Mantrom, D.D. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    A measurement capability using a horizontal array of 10 S4 current meters mounted on a stiff floating structure with 35 m aperture has been developed to support interpretation of radar imaging of surface effects associated with internal waves. This system has been fielded three times and most recently, has collected data alongside the sea-surface footprint of a land-fixed radar imaging ship-generated internal waves. The underlying need for this measurement capability is described. The specifications resulting from this need are presented and the engineering design and deployment procedures of the platform and systems that resulted are described The current meter data are multiplexed along with meteorological and system status data on board the floating platform and are telemetered to a shore station and on to a data acquisition system. The raw data are recorded, and are then processed to form space-time images of current and strain rate (a spatial derivative of the current field). Examples of raw and processed data associated with ship-generated internal waves are presented.

  14. A real time global seismic monitoring system at Gauribidanur array

    International Nuclear Information System (INIS)

    This paper presents the in-house development and results of a Windows application called GOD (Gauribidanur Online Detector) which detects seismic signals in real time from global earthquakes using Gauri Bidanur Array (GBA) data and provides the input to near real time reviewing software ViSWAS (Visual Seismic Waveform Analysis System). These two software systems together constitute a global seismic monitoring system, which facilitate real time detection, location and identification of all the relevant seismic events including the sub marine earthquakes.The signal detection software which is based on K-means clustering algorithm, an unsupervised learning method, uses eleven parameters to distinguish seismic signals from seismic noise and thereby detects the signals with negligible false triggers. The reviewing software ViSWAS on the other hand facilitates quick location and identification of seismic events. Both these software systems are meant for round the clock operation at the seismic data centre of BARC which estimates and communicates the event parameters in quickest possible time. The estimated parameters have been found to be in agreement with those reported by international seismological agencies like United States Geological Survey. (author)

  15. Receive channel architecture and transmission system for digital array radar

    OpenAIRE

    Yong, Yoke Chuang

    2005-01-01

    An â opportunistic arrayâ is a new digital antenna concept where phased array elements are placed at available open areas over the entire length of the platform. The elements are self-standing transmit-receive modules that require no hardwire connections other than prime power. All synchronization signals and data are passed wirelessly between the elements and a central signal processor. An opportunistic array that is integrated into the hull or superstructure of the warship is called an â...

  16. The Digital Motion Control System for the Submillimeter Array Antennas

    CERN Document Server

    Hunter, T R; Kimberk, R; Leiker, P S; Patel, N A; Blundell, R; Christensen, R D; Diven, A R; Maute, J; Plante, R J; Riddle, P; Young, K H

    2013-01-01

    We describe the design and performance of the digital servo and motion control system for the 6-meter diameter parabolic antennas of the Submillimeter Array (SMA) on Mauna Kea, Hawaii. The system is divided into three nested layers operating at a different, appropriate bandwidth. (1) A rack-mounted, real-time Unix system runs the position loop which reads the high resolution azimuth and elevation encoders and sends velocity and acceleration commands at 100 Hz to a custom-designed servo control board (SCB). (2) The microcontroller-based SCB reads the motor axis tachometers and implements the velocity loop by sending torque commands to the motor amplifiers at 558 Hz. (3) The motor amplifiers implement the torque loop by monitoring and sending current to the three-phase brushless drive motors at 20 kHz. The velocity loop uses a traditional proportional-integral-derivative (PID) control algorithm, while the position loop uses only a proportional term and implements a command shaper based on the Gauss error functi...

  17. 77 FR 52317 - Record of Decision for Surveillance Towed Array Sensor System Low Frequency Active Sonar

    Science.gov (United States)

    2012-08-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF DEFENSE Department of the Navy Record of Decision for Surveillance Towed Array Sensor System Low Frequency Active... Array Sensor System Low Frequency Active (SURTASS LFA) sonar systems with certain...

  18. Protein electrophoresis - serum

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003540.htm Protein electrophoresis - serum To use the sharing features on ... JavaScript. This lab test measures the types of protein in the fluid (serum) part of a blood ...

  19. Apertif - the focal-plane array system for the WSRT

    CERN Document Server

    Oosterloo, Tom; van Cappellen, Wim; Bakker, Laurens; Heald, George; Ivashina, Marianna

    2009-01-01

    We describe a focal plane array (FPA) system, called Apertif, that is being developed for the Westerbork Synthesis Radio Telescope (WSRT). The aim of Apertif is to increase the instantaneous field of view of the WSRT by a factor of 37 and its observing bandwidth to 300 MHz with high spectral resolution. This system will turn the WSRT into an effective survey telescope with scientific applications such as deep imaging surveys of the northern sky of HI and OH emission, of the polarised continuum and efficient searches for pulsars and transients. Such surveys will detect the HI in more than 100,000 galaxies out to z = 0.4, will allow to determine the detailed structure of the magnetic field of the Galaxy, and will discover more than 1,000 pulsars. We present experimental results obtained with a prototype FPA installed in one of the WSRT dishes. These results demonstrate that FPAs do have the performance that is required to make all these surveys possible.

  20. Non-destructive evaluation of welding part of stainless steels by phased array system

    International Nuclear Information System (INIS)

    Recently, more accurate and convenient Non-Destructive Evaluation techniques are required for flaw inspection of structural materials. Phased array ultrasonic transducers are expected as such as NDE technique but there are many subjects to be solved. Furthermore, commercial phased array systems with conventional scanning and imaging techniques have not fulfilled their maximum potential. The purpose of this paper is to improve the phased array system to be applicable to the inhomogeneity evaluation of welding part of stainless steels. (author)

  1. Performance Measurements of the Submillimeter Wave Astronomy Satellite (SWAS) Solar Array Deployment System

    OpenAIRE

    Sneiderman, Gary

    1995-01-01

    This paper discusses some unique features of the solar array deployment system used on the Submillimeter Wave Astronomy Satellite (SWAS). The mechanism system is highly optimized, incorporates no single-use components, and is fully testable in a one-"g" environment. A single High Output Paraffin (HOP) linear actuator drives the mechanisms used to deploy and lock each wing of solar array panels. The solar arrays open slowly, requiring only enough force to overcome inefficiencies and friction. ...

  2. Recent advances in preparative electrophoresis

    Science.gov (United States)

    Mosher, Richard A.; Thormann, Wolfgang; Egen, Ned B.; Couasnon, Pascal; Sammons, David W.

    1987-01-01

    Various approaches for preparative electrophoresis, and three new instruments for preparative electrophoresis are discussed. Consideration is given to isoelectric focusing, isotachophoresis, and zone electrophoresis, three gel-based electrophoresis methods. The design, functions, and performance of the Elphor VaP 21 device of Hannig (1982), the shear-stabilized BIOSTREAM separator of Thompson (1983), and the recycling isoelectric focusing device are described.

  3. A new sieving matrix for DNA sequencing, genotyping and mutation detection and high-throughput genotyping with a 96-capillary array system

    Energy Technology Data Exchange (ETDEWEB)

    Gao, David

    1999-11-08

    Capillary electrophoresis has been widely accepted as a fast separation technique in DNA analysis. In this dissertation, a new sieving matrix is described for DNA analysis, especially DNA sequencing, genetic typing and mutation detection. A high-throughput 96 capillary array electrophoresis system was also demonstrated for simultaneous multiple genotyping. The authors first evaluated the influence of different capillary coatings on the performance of DNA sequencing. A bare capillary was compared with a DB-wax, an FC-coated and a polyvinylpyrrolidone dynamically coated capillary with PEO as sieving matrix. It was found that covalently-coated capillaries had no better performance than bare capillaries while PVP coating provided excellent and reproducible results. The authors also developed a new sieving Matrix for DNA separation based on commercially available poly(vinylpyrrolidone) (PVP). This sieving matrix has a very low viscosity and an excellent self-coating effect. Successful separations were achieved in uncoated capillaries. Sequencing of M13mp18 showed good resolution up to 500 bases in treated PVP solution. Temperature gradient capillary electrophoresis and PVP solution was applied to mutation detection. A heteroduplex sample and a homoduplex reference were injected during a pair of continuous runs. A temperature gradient of 10 C with a ramp of 0.7 C/min was swept throughout the capillary. Detection was accomplished by laser induced fluorescence detection. Mutation detection was performed by comparing the pattern changes between the homoduplex and the heteroduplex samples. High throughput, high detection rate and easy operation were achieved in this system. They further demonstrated fast and reliable genotyping based on CTTv STR system by multiple-capillary array electrophoresis. The PCR products from individuals were mixed with pooled allelic ladder as an absolute standard and coinjected with a 96-vial tray. Simultaneous one-color laser-induced fluorescence

  4. Antenna Arrays for Tactical Communication Systems: A Comparative Study

    Directory of Open Access Journals (Sweden)

    L. Slama

    2011-12-01

    Full Text Available In this paper, we give a comparative study of several planar antenna concepts for reliable long range links in a tactical environment. The antenna elements are studied in terms of their electrical properties (bandwidth, reflection coefficient and radiation characteristics and construction (robustness and material consumption. First, we model single antenna elements to investigate if they meet the requirements. Second, we arrange the elements with the best features into 2x2 arrays. Computer simulations of the arrays are verified by measurements. Finally, we formulate recommendations for large array (8x8 or 16x16 elements synthesis to achieve the required properties.

  5. Cooling System for a Ka Band Transmit Antenna Array

    OpenAIRE

    Döring, Björn

    2006-01-01

    Active antenna arrays working at higher frequencies result in higher packaging densities. The antenna array under consideration operates at about 30 GHz and will be installed in an aircraft. Commercially available power amplifiers at these frequencies have an efficiency of typically 20 %, which results in high amounts of dissipated heat for the required high radiated power. The dissipated power, up to 9.5 kW as a worst case for a 50 × 50 element array, has to be transfered from the antenna to...

  6. Conducting Polymer Electrodes for Gel Electrophoresis

    OpenAIRE

    Bengtsson, Katarina; Nilsson, Sara; Robinson, Nathaniel D

    2014-01-01

    In nearly all cases, electrophoresis in gels is driven via the electrolysis of water at the electrodes, where the process consumes water and produces electrochemical by-products. We have previously demonstrated that p-conjugated polymers such as poly(3,4-ethylenedioxythiophene) (PEDOT) can be placed between traditional metal electrodes and an electrolyte to mitigate electrolysis in liquid (capillary electroosmosis/electrophoresis) systems. In this report, we extend our previous result to gel ...

  7. Multi-array control system for a wide-wavelength observation

    Science.gov (United States)

    Nakaya, Hidehiko; Sato, Shuji

    1998-08-01

    This paper presents an overview of the electronics multi- array control system design that can control several different types of focal plane arrays simultaneously. This system is used with the SUBARU standard data acquisition system MESIA. MACS2 and MESSIA materialize a wide wavelength observation at visible and near IR wavelengths that requires different types of arrays. MACS2 consists of four types of cards. An isolation card is required for one imaging system. A clock driver card and an ADC card are required for an array, and a preamp card is required for an ADC card. Each card is daisy-chained through differential signals. Every array does not have to be placed closely, and no more signal lines are required even when controlling more than one array and type. The bias voltages to operate arrays and the offset voltage at the analog input can be controlled and monitored form a host workstation. We can arrange various environments to evaluate focal plane arrays without any modifications of printed circuit boards or any wiring. MACS2 is very useful and powerful for evaluating different types of arrays. Also we could save time to swap a spare card when a card for whichever detector is broken, and the maintenance of a recent complex imaging system becomes easier. MACS2 will be installed in TRISPEC, two InSb, WFCT, SIRIUS.

  8. A logarithmic detection system suitable for a 4π array

    International Nuclear Information System (INIS)

    A low pressure multiwire proportional counter, a Bragg curve counter, and an array of CaF2/plastic scintillator telescope have been developed in a geometry suitable for close packing into a 4π detector designed to study nucleus-nucleus reactions at 100-200 MeV/nucleon. The multiwire counter is hexagonal in shape and gives X-Y position information using resistive charge division from nichrome-coated stretched polypropylene foils. The Bragg curve counter is a hexagonal pyramid with the charge taken from a Frisch gridded anode. A field shaping grid gives the Bragg curve counter a radial field. The scintillator telescopes are shaped as truncated triangular pyramids such that when stacked together they form a truncated hexagonal pyramid. The light signal of the CaF2-plastic combination is read with one phototube using a phoswich technique to seperate the ΔE signal from the E signal. The entire system has been tested so far for particles with 1<=Z<=18 and gives good position, charge, and time resolution. (orig.)

  9. Note: A resonating reflector-based optical system for motion measurement in micro-cantilever arrays

    Energy Technology Data Exchange (ETDEWEB)

    Sathishkumar, P.; Punyabrahma, P.; Sri Muthu Mrinalini, R.; Jayanth, G. R. [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India)

    2015-09-15

    A robust, compact optical measurement unit for motion measurement in micro-cantilever arrays enables development of portable micro-cantilever sensors. This paper reports on an optical beam deflection-based system to measure the deflection of micro-cantilevers in an array that employs a single laser source, a single detector, and a resonating reflector to scan the measurement laser across the array. A strategy is also proposed to extract the deflection of individual cantilevers from the acquired data. The proposed system and measurement strategy are experimentally evaluated and demonstrated to measure motion of multiple cantilevers in an array.

  10. Tensioned Rollable Ultra-light Solar array System (TRUSS) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — TRUSS is a structurally efficient solar array concept that utilizes a TRAC rollable boom and tension-stiffened structure to exceed the program requirements for very...

  11. Design and Analysis Tools for Deployable Solar Array Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Large, lightweight, deployable solar array structures have been identified as a key enabling technology for NASA with analysis and design of these structures being...

  12. Adaptive-array Electron Cyclotron Emission diagnostics using data streaming in a Software Defined Radio system

    International Nuclear Information System (INIS)

    Measurement of the Electron Cyclotron Emission (ECE) spectrum is one of the most popular electron temperature diagnostics in nuclear fusion plasma research. A 2-dimensional ECE imaging system was developed with an adaptive-array approach. A radio-frequency (RF) heterodyne detection system with Software Defined Radio (SDR) devices and a phased-array receiver antenna was used to measure the phase and amplitude of the ECE wave. The SDR heterodyne system could continuously measure the phase and amplitude with sufficient accuracy and time resolution while the previous digitizer system could only acquire data at specific times. Robust streaming phase measurements for adaptive-arrayed continuous ECE diagnostics were demonstrated using Fast Fourier Transform (FFT) analysis with the SDR system. The emission field pattern was reconstructed using adaptive-array analysis. The reconstructed profiles were discussed using profiles calculated from coherent single-frequency radiation from the phase array antenna

  13. Capillary electrophoresis study on segment/segment system for segments based on phase of mixed micelles and its role in transport of particles between the two segments.

    Science.gov (United States)

    Oszwałdowski, Sławomir; Kubáň, Pavel

    2015-09-18

    Capillary electrophoresis coupled with contactless conductivity detector was applied to characterize BGE/segment/segment/BGE and BGE/segment/electrolyte/segment/BGE systems, where segment is the phase of mixed micelles migrating surrounded by BGE and composition of the first segment≠second segment. It was established that both systems are subject of evolution during electrophoretic run induced by different electrophoretic mobilities of segments and the phenomenon that generates the evolution is exchange of micelles between the two segments. This leads to segments re-equilibration during a run, which generates sub-zones from the two segments in the form of a cumulative zone or two isolated zones, depending on the injection scheme applied. Further analysis based on the system BGE/segment/electrolyte/segment/BGE shows that electrolyte solution between segments can act as a spacer to isolate the two micellar segments, and thereby to control the exchange of micelles between the two segments. Established features for both systems were further implemented towards characterization of the transport of nanocrystals (NCs) between two segments using CE/UV-vis technique and two examples were discussed: (i) on-line coating of NCs with surfactants and (ii) distribution of NCs between segments. The former aspect was found to be useful to discuss the state of particle in micellar media, whereas the latter shows system ability for the transport of NCs from the first segment or BGE based sample to the second segment, controlled by the electrolyte characteristics. It was concluded that transport of micelles and NCs is the subject of the same phenomena since basic electrolyte characteristics, i.e. length and concentration, act in the same way. This means that NCs in these systems can play the role of pseudomicelles, which mimic behaviour of micelles. Definitely, the tools established in the present work can be used to examine dynamic phenomena for pseudophase during electrophoresis

  14. An accurate determination of human grawth hormone content in different pituitary extracts, using a radioimmunoassay with polyacrylamide gel electrophoresis as a bound-free separation system

    International Nuclear Information System (INIS)

    Human growth hormone was extracted and purified according to the method of Roos et al. A first control of its purification and integrity was performed through molecular weight determination by gel filtration on Sephadex G-100 and on plyacrylamide gel electrophoresis (PAGE). Its biological activity was confirmed by the growth promoted in non-hypophysectomized rats at plateau. The main object, however, was the setting up of an accurate, reproducible method that could furnish the more absolute and comparable value of rafioimmunoassayable HGH content in perfect agreement with the results obtained by other laboratories. This was accomplished through a radioimmunoassay system that uses HGH labelled with 125I, where the separation of the bound from the free antigen is achieved on polyacrylamide gel electrophoresis, by a modification introduced in the original method of Davis. The resulting values, extremely close to that stated by the KABI-Laboratories (Stockolm), through obtained in quite different conditions of incubation, antibody concentration and with no use of second antibody, represent a confident approach to a comparable measure of this hormone in extract, which can also be applied to plasma determinations

  15. Fast methods for analysis of neurotransmitters from single cell and monitoring their releases in central nervous system by capillary electrophoresis, fluorescence microscopy and luminescence imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Ziqiang

    1999-12-10

    Fast methods for separation and detection of important neurotransmitters and the releases in central nervous system (CNS) were developed. Enzyme based immunoassay combined with capillary electrophoresis was used to analyze the contents of amino acid neurotransmitters from single neuron cells. The release of amino acid neurotransmitters from neuron cultures was monitored by laser induced fluorescence imaging method. The release and signal transduction of adenosine triphosphate (ATP) in CNS was studied with sensitive luminescence imaging method. A new dual-enzyme on-column reaction method combined with capillary electrophoresis has been developed for determining the glutamate content in single cells. Detection was based on monitoring the laser-induced fluorescence of the reaction product NADH, and the measured fluorescence intensity was related to the concentration of glutamate in each cell. The detection limit of glutamate is down to 10{sup {minus}8} M level, which is 1 order of magnitude lower than the previously reported detection limit based on similar detection methods. The mass detection limit of a few attomoles is far superior to that of any other reports. Selectivity for glutamate is excellent over most of amino acids. The glutamate content in single human erythrocyte and baby rat brain neurons were determined with this method and results agreed well with literature values.

  16. Study of acoustic signal in the process of resistance spot welding based on array sensor system

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This investigation was performed to study acoustic field signal in order to improve RSW quality. Researchers firstly built an acoustic array sensor system, which included 8 MPA-416 acoustic sensors, data acquisition card and LabVIEW. The system obtained the acoustic field information in the process of nugget growing. Due to the nonlinearity field signal, array sensor algorithm was utilized to quantitatively analyze the characteristics of acoustic field and reduced noise. The experiment and calculation results show that array sensor system can acquire acoustic field signal of nugget growing in the RSW process and array processing algorithm based on acoustic field can extract characteristic parameters to evaluate RSW quality. It was concluded that the acoustic array sensor system offers a new methodology for RSW quality inspection.

  17. Advances in capillary electrophoresis

    International Nuclear Information System (INIS)

    In the 1980s, capillary electrophoresis (CE) developed rapidly into a first-class analytical separation technique. Its advances in instru-mentation and method development will not only enhance or complement existing mature separation techniques such as liquid chromatography and conventional slab gel electrophoresis, but will also severely challenge these separation methods. A brief overview of most striking achievement of CE in the 1980s is given, which illustrates the challenge to liquid chromatography and conventional slab gel electrophoresis, and some detailed discussions are presented to highlight the advantages of CE. New developments in CE that can be expected for the 1990s include especially column technology, separation chemistry and instrumentation, which will serve further to diversify and improve the applicability of this technique in areas which are poorly addressed by other separation methods. This paper considers and speculates on the technological advancements that can be expected to emerge for CE in the 1990s. (author). 95 refs.; 14 figs

  18. The systems impact of a concentrated solar array on a Jupiter orbiter

    Science.gov (United States)

    Rockey, D. E.; Bamford, R.; Hollars, M. G.; Klemetson, R. W.; Koerner, T. W.; Marsh, E. L.; Price, H.; Uphoff, C.

    1981-01-01

    Results of a study are presented suggesting that a Galileo Jupiter orbiting mission could be performed with a concentrated solar array power source. A baseline spacecraft design using concentrated arrays is given, and the overall spacecraft implications for attitude control, propulsion, power conditioning and the resultant spacecraft mass are examined. It is noted that while the concentrated array concept still requires extensive development effort, no insurmountable system level barriers preclude the use of a concentrated solar array on this difficult mission, with its stressing radiation environment, its lengthy periods of spacecraft shadowing as it passes behind Jupiter, and, finally, its large delta v burn required for orbital insertion.

  19. High-resolution imaging using a wideband MIMO radar system with two distributed arrays.

    Science.gov (United States)

    Wang, Dang-wei; Ma, Xiao-yan; Chen, A-Lei; Su, Yi

    2010-05-01

    Imaging a fast maneuvering target has been an active research area in past decades. Usually, an array antenna with multiple elements is implemented to avoid the motion compensations involved in the inverse synthetic aperture radar (ISAR) imaging. Nevertheless, there is a price dilemma due to the high level of hardware complexity compared to complex algorithm implemented in the ISAR imaging system with only one antenna. In this paper, a wideband multiple-input multiple-output (MIMO) radar system with two distributed arrays is proposed to reduce the hardware complexity of the system. Furthermore, the system model, the equivalent array production method and the imaging procedure are presented. As compared with the classical real aperture radar (RAR) imaging system, there is a very important contribution in our method that the lower hardware complexity can be involved in the imaging system since many additive virtual array elements can be obtained. Numerical simulations are provided for testing our system and imaging method. PMID:20051345

  20. W-band Phased Array Systems using Silicon Integrated Circuits

    Science.gov (United States)

    Kim, Sang Young

    This thesis presents the silicon-based on-chip W-band phased array systems. An improved quadrature all-pass filter (QAF) and its implementation in 60--80 GHz active phase shifter using 0.13 microm SiGe BiCMOS technology is presented. It is demonstrated that with the inclusion of an Rs/R in the high Q branches of C and L, the sensitivity to the loading capacitance, therefore the I/Q phase and amplitude errors are minimized. This technique is especially suited for wideband millimeter-wave circuits where the loading capacitance (CL) is comparable to the filter capacitance (C). A prototype 60--80 GHz active phased shifter using the improved QAF is demonstrated. The overall chip size is 1.15 x 0.92 mm2 with the power consumption of 108 mW. The measured S11 and S22 are switches is demonstrated. The phase shifter is based on a low-pass pi-network. The chip size is 0.45 x 0.3 mm2 without pads and consumes virtually no power. The measured S11 and S22 is 8 dBm and the simulated IIP3 is > 22 dBm. A low-power 76--84 GHz 4-element phased array receiver using the designed passive phase shifter is presented. The power consumption is minimized by using a single-ended design and alternating the amplifiers and phase shifter cells to result in a low noise figure at a low power consumption. A variable gain amplifier and the 11° phase shifter are used to correct for the rms gain and phase errors at different operating frequencies. The overall chip size is 2.0 x 2.7 mm2 with the current consumption of 18 mA/channel with 1.8 V supply voltage. The measured S11 and S 22 is chip coupling is circuits are designed differentially to result in less sensitivity to packaging effect and high channel-to-channel isolation. The overall chip size is 5.0 x 5.8 mm 2 with the power consumption of 500--600 mA from 2 V supply voltage. The measured S11 and S22 for all 16 phase states is 10 dB for 76.4--90 GHz with the rms gain error of -45 dB. The measured NF is 11.2--13 dB at 77--87 GHz at the maximum

  1. Microcomputer Based System to control the Load of a Capacitor Array in the TJ-1 Tokamak

    International Nuclear Information System (INIS)

    The power to create the magnetic fields in the TJ-1 Tokamak is provides by an array of 16 capacitor sets. The total capacity of this array is 8. 1F. This work describes a computer system based on the Motorola M-6800 micro- processor which controls the load of the capacitor set and stablished the conditions for the reactor trigger. (Author)

  2. Microcomputer based system to control the load of a capacitor array in the TJ-1 Tokamak

    International Nuclear Information System (INIS)

    The power to create the magnetic field in the TJ-1 TOKAMAK is provide by an array of 16 capacitor sets. The total capacity of this array is 8.1F. This work describes a computer system based on the Motorola M-6800 microprocessor which controls the load of the capacitor set-and establishes the conditions for the reactor trigger. (author)

  3. DNA ELECTROPHORESIS AT SURFACES

    Energy Technology Data Exchange (ETDEWEB)

    RAFAILOVICH, MIRIAM; SOKOLOV, JONATHAN; GERSAPPE, DILIP

    2003-09-01

    During this year we performed two major projects: I. We developed a detailed theoretical model which complements our experiments on surface DNA electrophoresis. We found that it was possible to enhance the separation of DNA chains by imposing a chemical nanoscale pattern on the surface. This approach utilized the surface interaction effect of the DNA chains with the substrate and is a refinement to our previous method in which DNA chains were separated on homogeneous flat surfaces. By introducing the nano-patterns on the surface, the conformational changes of DNA chains of different lengths can be amplified, which results in the different friction strengths with the substrate surface. Our results also show that, when compared to the DNA electrophoresis performed on homogeneous flat surfaces, nanopatterned surfaces offer a larger window in choosing different surface interactions to achieve separation. II. In collaboration with a large international manufacturer of skin care products we also embarked on a project involving photo toxicity of titanium dioxide nanoparticles, which are a key ingredient in sunscreen and cosmetic lotions. The results clearly implicated the nanoparticles in catalyzing damage to chromosomal DNA. We then used this knowledge to develop a polymer/anti-oxidant coating which prevented the photocatalytic reaction on DNA while still retaining the UV absorptive properties of the nanoparticles. The standard gel electrophoresis was not sufficient in determining the extent of the DNA damage. The conclusions of this study were based predominantly on analysis obtained with the surface electrophoresis method.

  4. Sensorless PV Array Diagnostic Method for Residential PV Systems

    DEFF Research Database (Denmark)

    Sera, Dezso; Spataru, Sergiu; Mathe, Laszlo; Kerekes, Tamas; Teodorescu, Remus

    This work proposes a temperature and irradiance sensorless diagnostic method suitable for small residential PV installations, focusing on detection of partial shadows. The method works by detection of failures in crystalline silicone PV arrays by concomitant monitoring of some of their key...

  5. VERITAS The Very Energetic Radiation Imaging Telescope Array System

    CERN Document Server

    Weekes, T C; Biller, S D; Breslin, A C; Buckley, J H; Carter-Lewis, D A; Catanese, M; Cawley, M F; Dingus, B L; Fazio, G G; Fegan, D J; Finley, J; Fishman, G; Gaidos, J A; Gillanders, G H; Gorham, P W; Grindlay, J E; Hillas, A M; Huchra, J P; Kaaret, P E; Kertzman, M P; Kieda, D B; Krennrich, F; Lamb, R C; Lang, M J; Marscher, A P; Matz, S; McKay, T; Müller, D; Ong, R; Purcell, W; Rose, J; Sembroski, G H; Seward, F D; Slane, P O; Swordy, S P; Tümer, T O; Ulmer, M P; Urban, M; Wilkes, B J

    1997-01-01

    A next generation atmospheric Cherenkov observatory is described based on the Whipple Observatory $\\gamma$-ray telescope. A total of nine such imaging telescopes will be deployed in an array that will permit the maximum versatility and give high sensitivity in the 50 GeV - 50 TeV band (with maximum sensitivity from 100 GeV to 10 TeV).

  6. Automated Non-Destructive Testing Array Evaluation System

    International Nuclear Information System (INIS)

    Utilities perform eddy current tests on nuclear power plant steam generator (SG) tubes to detect degradation. This report summarizes the status of ongoing research to develop signal processing algorithms that automate analysis of eddy current test data. The research focuses on analyzing array probe data for detecting, classifying, and characterizing degradation in SG tubes

  7. Automated Non-Destructive Testing Array Evaluation System

    Energy Technology Data Exchange (ETDEWEB)

    Wei, T.; Zavaljevski, N.; Bakhtiari, S.; Miron, A.; Jupperman, D.

    2004-12-31

    Utilities perform eddy current tests on nuclear power plant steam generator (SG) tubes to detect degradation. This report summarizes the status of ongoing research to develop signal processing algorithms that automate analysis of eddy current test data. The research focuses on analyzing array probe data for detecting, classifying, and characterizing degradation in SG tubes.

  8. A Circular aperture-array structure optical system for digital sun sensor

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Based on the first type of Rayleigh Sommerfeld diffraction formula, an imaging model of circular aperture-array structure digital sun sensor optical system is developed. Then a 6×6 circular aperture-array structure optical system is designed. The results of numerical simulation show that the optical system is designed well and is conformed to the requirements of miniaturization and high accuracy of sun sensor.

  9. Design and Realization of Phased Array Radar Optical Fiber Transmission System

    Institute of Scientific and Technical Information of China (English)

    HU Shan-qing; LIU Feng; LONG Teng

    2007-01-01

    One optical fiber transmission system is designed.The modularization optical fiber transmission adapters were utilized in the system,so the system structure could be flexibly scalable.The sub-array adapter and signal processor adapter were designed and realized utilizing the new field programmable gate array (FPGA) which could drive the optical transceiver.The transmission agreement was designed based on the data stream.In order to solve the signal synchronization problem of the optical fiber transmitted phased array radar,a method named synchronous clock was designed.The fiber transmission error code rate of the system was zero with an experimental transmission velocity of 800 Mbit/s.The phased array radar system has detected the airplane target,thus validated the feasibility of the design method.

  10. Microbeam-coupled capillary electrophoresis

    International Nuclear Information System (INIS)

    Within the first few microseconds following a charged particle traversal of a cell, numerous oxygen and nitrogen radicals are formed along the track. Presented here is a method, using capillary electrophoresis, for simultaneous measurement, within an individual cell, of specific reactive oxygen species, such as the superoxide radical (O2-*) as well as the native and oxidised forms of glutathione, an ubiquitous anti-oxidant that assists the cell in coping with these species. Preliminary data are presented as well as plans for integrating this system into the charged particle microbeam at Columbia University. (authors)

  11. Automation and integration of multiplexed on-line sample preparation with capillary electrophoresis for DNA sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Tan, H.

    1999-03-31

    The purpose of this research is to develop a multiplexed sample processing system in conjunction with multiplexed capillary electrophoresis for high-throughput DNA sequencing. The concept from DNA template to called bases was first demonstrated with a manually operated single capillary system. Later, an automated microfluidic system with 8 channels based on the same principle was successfully constructed. The instrument automatically processes 8 templates through reaction, purification, denaturation, pre-concentration, injection, separation and detection in a parallel fashion. A multiplexed freeze/thaw switching principle and a distribution network were implemented to manage flow direction and sample transportation. Dye-labeled terminator cycle-sequencing reactions are performed in an 8-capillary array in a hot air thermal cycler. Subsequently, the sequencing ladders are directly loaded into a corresponding size-exclusion chromatographic column operated at {approximately} 60 C for purification. On-line denaturation and stacking injection for capillary electrophoresis is simultaneously accomplished at a cross assembly set at {approximately} 70 C. Not only the separation capillary array but also the reaction capillary array and purification columns can be regenerated after every run. DNA sequencing data from this system allow base calling up to 460 bases with accuracy of 98%.

  12. Photovoltaic array with minimally penetrating rooftop support system

    Science.gov (United States)

    Lenox, Carl J.S.

    2012-10-23

    A photovoltaic array including a plurality of photovoltaic assemblies and a plurality of mounting units. The mounting units each include an elongate rail and a plurality of leg assemblies. The rail is sized and configured to maintain a portion of at least two of the photovoltaic assemblies, with the leg assemblies extending from the rail in a spaced-apart fashion and terminating in a foot for placement against a rooftop structure for minimally penetration installation. Further, at least one of the leg assemblies can include a retractable leg. When the photovoltaic array is installed to a rooftop structure including a membrane intermittently secured to a rooftop deck, the retractable leg accommodates upward billowing of the membrane under windy conditions.

  13. The Very Energetic Radiation Imaging Telescope Array System (VERITAS)

    CERN Document Server

    Bradbury, S M; Breslin, A C; Buckley, J H; Carter-Lewis, D A; Catanese, M; Criswell, S; Dingus, B L; Fegan, D J; Finley, J P; Gaidos, J A; Grindlay, J; Hillas, A M; Harris, K; Hermann, G; Kaaret, P E; Kieda, D B; Knapp, J; Krennrich, F; Le Bohec, S; Lessard, R W; Lloyd-Evans, J; McKernan, B; Müller, D; Ong, R; Quenby, J J; Quinn, J; Rochester, G D; Rose, H J; Salamon, M B; Sembroski, G H; Sumner, T J; Swordy, S P; Vasilev, V; Weekes, T C

    1999-01-01

    We give an overview of the current status and scientific goals of VERITAS, a proposed hexagonal array of seven 10 m aperture imaging Cherenkov telescopes. The selected site is Montosa Canyon (1390 m a.s.l.) at the Whipple Observatory, Arizona. Each telescope, of 12 m focal length, will initially be equipped with a 499 element photomultiplier camera covering a 3.5 degree field of view. A central station will initiate the readout of 500 MHz FADCs upon receipt of multiple telescope triggers. The minimum detectable flux sensitivity will be 0.5% of the Crab Nebula flux at 200 GeV. Detailed simulations of the array's performance are presented elsewhere at this meeting. VERITAS will operate primarily as a gamma-ray observatory in the 50 GeV to 50 TeV range for the study of active galaxies, supernova remnants, pulsars and gamma-ray bursts.

  14. Design and Performance of the ARIANNA Hexagonal Radio Array Systems

    CERN Document Server

    Barwick, S W; Besson, D Z; Cheim, E; Duffin, T; Hanson, J C; Klein, S R; Kleinfelder, S A; Prakash, T; Piasecki, M; Ratzlaff, K; Reed, C; Roumi, M; Samanta, A; Stezelberger, T; Tatar, J; Walker, J; Young, R; Zou, L

    2014-01-01

    We report on the development, installation and operation of the first three of seven stations deployed at the ARIANNA site's pilot Hexagonal Radio Array in Antarctica. The primary goal of the ARIANNA project is to observe ultra-high energy (>100 PeV) cosmogenic neutrino signatures using a large array of autonomous stations each dispersed 1 km apart on the surface of the Ross Ice Shelf. Sensing radio emissions of 100 MHz to 1 GHz, each station in the array contains RF antennas, amplifiers, 1.92 G-sample/s, 850 MHz bandwidth signal acquisition circuitry, pattern-matching trigger capabilities, an embedded CPU, 32 GB of solid-state data storage, and long-distance wireless and satellite communications. Power is provided by the sun and LiFePO4 storage batteries, and the stations consume an average of 7W of power. Operation on solar power has resulted in >=58% per calendar-year live-time. The station's pattern-trigger capabilities reduce the trigger rates to a few milli-Hertz with 4-sigma thresholds while retaining ...

  15. Plasma Interactions with High Voltage Solar Arrays for a Direct Drive Hall Effect Thruster System

    Science.gov (United States)

    Schneider, T.; Horvater, M. A.; Vaughn, J.; Carruth, M. R.; Jongeward, G. A.; Mikellides, I. G.

    2003-01-01

    The Environmental Effects Group of NASA s Marshall Space Flight Center (MSFC) is conducting research into the effects of plasma interaction with high voltage solar arrays. These high voltage solar arrays are being developed for a direct drive Hall Effect Thruster propulsion system. A direct drive system configuration will reduce power system mass by eliminating a conventional power-processing unit. The Environmental Effects Group has configured two large vacuum chambers to test different high-voltage array concepts in a plasma environment. Three types of solar arrays have so far been tested, an International Space Station (ISS) planar array, a Tecstar planar array, and a Tecstar solar concentrator array. The plasma environment was generated using a hollow cathode plasma source, which yielded densities between 10(exp 6) - 10(exp 7) per cubic centimeter and electron temperatures of 0.5-1 eV. Each array was positioned in this plasma and biased in the -500 to + 500 volt range. The current collection was monitored continuously. In addition, the characteristics of arcing, snap over, and other features, were recorded. Analysis of the array performance indicates a time dependence associated with the current collection as well as a tendency for "conditioning" over a large number of runs. Mitigation strategies, to reduce parasitic current collection, as well as arcing, include changing cover-glass geometry and layout as well as shielding the solar cell edges. High voltage performance data for each of the solar array types tested will be presented. In addition, data will be provided to indicate the effectiveness of the mitigation techniques.

  16. High-gain textile antenna array system for off-body communication

    OpenAIRE

    Dries Vande Ginste; Hendrik Rogier; Luigi Vallozzi; Maria Lucia Scarpello

    2012-01-01

    A novel high-gain textile antenna array system, fully integrated into a rescue-worker’s vest and operating in the Industrial, Scientific, and Medical wireless band (2.4–2.4835 GHz), is presented. The system comprises an array consisting of four tip-truncated equilateral triangular microstrip patch antennas (ETMPAs), a power divider, line stretchers, and coaxial cables. The array is vertically positioned on the human torso to produce a narrow beam in elevation, as such reducing fading and allo...

  17. The calibration system for the photomultiplier array of the SNO+ experiment

    OpenAIRE

    Alves, R; Andringa, S.; Bradbury, S; Carvalho, J.; Chauhan, D; Clark, K.; Coulter, I; Descamps, F.; Falk, E; Gurriana, L.; Kraus, C.; Lefeuvre, G.; Maio, A.; Maneira, J.; Mottram, M.

    2015-01-01

    A light injection system using LEDs and optical fibres was designed for the calibration and monitoring of the photomultiplier array of the SNO+ experiment at SNOLAB. Large volume, non-segmented, low-background detectors for rare event physics, such as the multi-purpose SNO+ experiment, need a calibration system that allow an accurate and regular measurement of the performance parameters of their photomultiplier arrays, while minimising the risk of radioactivity ingress. The design implemented...

  18. Miniaturized capillary electrophoresis system with ultraviolet photometric detection combined with flow injection sample introduction using a modified falling-drop interface

    International Nuclear Information System (INIS)

    A miniaturized capillary electrophoresis (CE) system with UV-Vis detection was coupled to a flow injection (FI) system for achieving high throughput continuous sample introduction. The cassette of a commercial CE instrument was modified to hold a 6.5 cm long silica capillary and a flow-through waste reservoir. The cassette was inserted into the flow-cell chamber of a commercial UV detector, with the light beam focused on the capillary and collected by two ball lenses on the cassette. The capillary inlet, left outside the cassette and detector, was positioned on the top of a vertical 3.5 mm diameter glass rod, in close contact with an electrode. Samples injected through the FI system dropped freely on top of the pillar, covering the capillary inlet and electrode. Continuous sample introduction was achieved for CE separations under non-interrupted separation voltage, which was isolated from the FI system through the discontinuity of droplets. The newly developed interface and UV detection system was used for fast separation of sulphamethoxazole (SMZ) and trimethoprim (TMP) in sulphatrim tablets, achieving a high throughput of over 48 h-1, and a low carryover of 2%. Separation efficiencies of 8 μm plate height and detection limits of 1.0 mg l-1 for SMZ and 0.5 mg l-1 (3σ) for TMP were obtained

  19. Design of a Solar Motor Drive System Fed by a Direct-Connected Photovoltaic Array

    Directory of Open Access Journals (Sweden)

    AYDOGMUS, O.

    2012-08-01

    Full Text Available A solar motor pump drive system is modeled and simulated. The proposed drive system does not require any kind of energy storage system and dc-dc converter. The system is connected directly to a photovoltaic (PV array. Thus, a low cost solar system can be achieved. A vector controlled Permanent Magnet Synchronous Motor (PMSM is used as a solar motor to increase the efficiency of system. The motor is designed for a low rated voltage level about 24V. The hill climbing MPPT method is used for balanced the motor power and PV power to obtain a high efficiency. The results are performed by using MATLAB/SimPowerSystem blocks. In addition, the PV array is modeled to allow for the possibility of running as on-line adjustable in simulation environment without using lookup table. The performances of motor, MPPT and drive system are analyzed in different conditions as temperature and irradiation of PV array.

  20. Advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) Small Spacecraft System

    Science.gov (United States)

    Lockett, Tiffany Russell; Martinez, Armando; Boyd, Darren; SanSouice, Michael; Farmer, Brandon; Schneider, Todd; Laue, Greg; Fabisinski, Leo; Johnson, Les; Carr, John A.

    2015-01-01

    This paper describes recent advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) currently being developed at NASA's Marshall Space Flight Center. The LISA-T array comprises a launch stowed, orbit deployed structure on which thin-film photovoltaic (PV) and antenna devices are embedded. The system provides significant electrical power generation at low weights, high stowage efficiency, and without the need for solar tracking. Leveraging high-volume terrestrial-market PVs also gives the potential for lower array costs. LISA-T is addressing the power starvation epidemic currently seen by many small-scale satellites while also enabling the application of deployable antenna arrays. Herein, an overview of the system and its applications are presented alongside sub-system development progress and environmental testing plans.

  1. Design and development of a brushless, direct drive solar array reorientation system

    Science.gov (United States)

    Jessee, R. D.

    1972-01-01

    This report covers the design and development of the laboratory model, and is essentially a compilation of reports covering the system and its various parts. To enhance completeness, the final report of Phase 1 covering circuit development of the controller is also included. A controller was developed for a brushless, direct-drive, single axis solar array reorientation system for earth-pointed, passively-stabilized spacecraft. A control systems was designed and breadboard circuits were built and tested for performance. The controller is designed to take over automatic control of the array on command after the spacecraft is stabilized in orbit. The controller will orient the solar array to the sun vector and automatically track to maintain proper orientation. So long as the orbit is circular, orientation toward the sun is maintained even though the spacecraft goes into the shadow of the earth. Particular attention was given in the design to limit reaction between the array and the spacecraft.

  2. A Logarithmic Detection System Suitable for a 4π Array

    OpenAIRE

    Westfall, G.D.; Yurkon, J.E.; Van der Plicht, J.; Koenig, Z.M.; Jacak, B. V.; Fox, R; Crawley, G.M.; Maier, M.R.; Hasselquist, B.E.; Tickle, R.S.; Horn, D.

    1985-01-01

    A low pressure multiwire proportional counter, a Bragg curve counter, and an array of CaF2/plastic scintillator telescopes have been developed in a geometry suitable for close packing into a 4π detector designed to study nucleus-nucleus reactions at 100-200 MeV/nucleon. The multiwire counter is hexagonal in shape and gives X-Y position information using resistive charge division from nichrome-coated stretched polypropylene foils. The Bragg curve counter is a hexagonal pyramid with the charge ...

  3. Development of Atmospheric Monitoring System at Akeno Observatory for the Telescope Array Project

    CERN Document Server

    Yamamoto, T; Chikawa, M; Hayashida, N; Kawakami, S; Minagawa, N; Morizane, Y; Sasano, M; Yasui, K

    2002-01-01

    We have developed an atmospheric monitoring system for the Telescope Array experiment at Akeno Observatory. It consists of a Nd:YAG laser with an alt-azimuth shooting system and a small light receiver. This system is installed inside an air conditioned weather-proof dome. All parts, including the dome, laser, shooter, receiver, and optical devices are fully controlled by a personal computer utilizing the Linux operating system. It is now operated as a back-scattering LIDAR System. For the Telescope Array experiment, to estimate energy reliably and to obtain the correct shower development profile, the light transmittance in the atmosphere needs to be calibrated with high accuracy. Based on observational results using this monitoring system, we consider this LIDAR to be a very powerful technique for Telescope Array experiments. The details of this system and its atmospheric monitoring technique will be discussed.

  4. Separation of native allophycocyanin and R-phycocyanin from marine red macroalga Polysiphonia urceolata by the polyacrylamide gel electrophoresis performed in novel buffer systems.

    Directory of Open Access Journals (Sweden)

    Yu Wang

    Full Text Available Three buffer systems of Imidazole-Acetic acid, HEPES-Imidazole/Bis-tris and Bis-tris-HEPES-MES were designed based on the principle of discontinuous polyacrylamide gel electrophoresis (PAGE for the native PAGE which could be performed in pH 7.0 and 6.5 in order to analyze and prepare the minor components of allophycocyanin (AP and R-phycocyanin (R-PC from marine red macroalga Polysiphonia urceolata. These AP and R-PC phycobiliproteins are easily denatured in alkaline environments. The obtained results demonstrated that the PAGE modes performed in the buffer systems of HEPES-Imidazole/Bis-tris and Bis-tris-HEPES-MES gave the satisfactory resolution and separation of AP and R-PC proteins. The absorption and fluorescence spectra of the AP and R-PC proteins which were prepared by the established PAGE modes proved that they maintained natural spectroscopic characteristics. The established PAGE modes may also provide useful references and selections for some other proteins that are sensitive to alkaline environments or are not effectively separated by the classical PAGE modes performed normally in alkaline buffer systems.

  5. Separation of Native Allophycocyanin and R-Phycocyanin from Marine Red Macroalga Polysiphonia urceolata by the Polyacrylamide Gel Electrophoresis Performed in Novel Buffer Systems

    Science.gov (United States)

    Wang, Yu; Gong, Xueqin; Wang, Shumei; Chen, Lixue; Sun, Li

    2014-01-01

    Three buffer systems of Imidazole−Acetic acid, HEPES−Imidazole/Bis-tris and Bis-tris−HEPES−MES were designed based on the principle of discontinuous polyacrylamide gel electrophoresis (PAGE) for the native PAGE which could be performed in pH 7.0 and 6.5 in order to analyze and prepare the minor components of allophycocyanin (AP) and R-phycocyanin (R-PC) from marine red macroalga Polysiphonia urceolata. These AP and R-PC phycobiliproteins are easily denatured in alkaline environments. The obtained results demonstrated that the PAGE modes performed in the buffer systems of HEPES−Imidazole/Bis-tris and Bis-tris−HEPES−MES gave the satisfactory resolution and separation of AP and R-PC proteins. The absorption and fluorescence spectra of the AP and R-PC proteins which were prepared by the established PAGE modes proved that they maintained natural spectroscopic characteristics. The established PAGE modes may also provide useful references and selections for some other proteins that are sensitive to alkaline environments or are not effectively separated by the classical PAGE modes performed normally in alkaline buffer systems. PMID:25166028

  6. Non-Aqueous Capillary Electrophoresis

    Science.gov (United States)

    Szumski, Michał; Buszewski, Bogusław

    Non-aqueous capillary electrophoresis and capillary electrochromatography are special variants of these techniques. Here, organic solvents or their mixtures with or without dissolved electrolytes are used as separation buffer or mobile phase, respectively. The most important features of non-aqueous systems are: better solubility of more hydrophobic ionic substances (many natural products) than in water, much less current and Joule heating allows for using highly concentrated buffers and/or larger capillary internal diameters, polar interactions are enhanced in organic solvents which is often highly advantageous in chiral separation systems. This chapter presents most frequently used solvents, their properties, as well as shows pH* scale which is often used in non-aqueous systems.

  7. Wide-viewing-angle three-dimensional display system using HOE lens array

    Science.gov (United States)

    Takahashi, Hideya; Fujinami, Hiromitsu; Yamada, Kenji

    2006-02-01

    Integral imaging has the problem of the limitation of viewing angle. This paper describes a wide-viewing-angle 3D display system using holographic optical element (HOE) lens array. This display system consists of a flat HOE lens array and a projector. However, the axis of each elemental HOE lens is eccentric. Since every axis of the elemental HOE lens is convergent, the flat HOE lens array works as a virtual curved lens array. Thus, this display system has a wide viewing angle. On the other hand, generally, in a integral imaging system each elemental lens has its corresponding area on the display panel. To prevent the image flipping, the elemental image that exceeds the corresponding area is discarded. Therefore, the number of the elemental images is limited and the viewing angle is limited. In the proposed system, since the HOE lens array is flat and the light rays from the projector are parallel, the elemental image does not exceed the corresponding area and the flipped images are not observed. Also, the configuration of this display system is simple. The principle of the proposed system is explained and the experimental result is presented.

  8. Proof of Concept of an Irradiance Estimation System for Reconfigurable Photovoltaic Arrays

    OpenAIRE

    Vincenzo Li Vigni; Damiano La Manna; Eleonora Riva Sanseverino; Vincenzo di Dio; Pietro Romano; Pietro di Buono; Maurizio Pinto; Rosario Miceli; Costantino Giaconia

    2015-01-01

    In order to reduce the mismatch effect caused by non-uniform shadows in PV arrays, reconfigurable interconnections approaches have been recently proposed in the literature. These systems usually require the knowledge of the solar radiation affecting every solar module. The aim of this work is to evaluate the effectiveness of three irradiance estimation approaches in order to define which can be well suited for reconfigurable PV arrays. It is presented a real-time solar irradiance estimation d...

  9. Detection of impulsive sources from an aerostat-based acoustic array data collection system

    Science.gov (United States)

    Prather, Wayne E.; Clark, Robert C.; Strickland, Joshua; Frazier, Wm. Garth; Singleton, Jere

    2009-05-01

    An aerostat based acoustic array data collection system was deployed at the NATO TG-53 "Acoustic Detection of Weapon Firing" Joint Field Experiment conducted in Bourges, France during the final two weeks of June 2008. A variety of impulsive sources including mortar, artillery, gunfire, RPG, and explosive devices were fired during the test. Results from the aerostat acoustic array will be presented against the entire range of sources.

  10. Novel microstrip antenna array for anti-jam satellite navigation system

    OpenAIRE

    Martynyuk, Sergiy Ye.; Vasylenko, Dmytro O.; Dubrovka, Fedor F.; Laush, Anatolii G.

    2015-01-01

    We present results of theoretical and experimental investigations of a novel dual band right hand circularly polarized microstrip antenna array with adaptive space-time processing capability for terminal of GPS/GLONASS/GALILEO satellite navigation systems. The array structure is composed from 10 microstrip radiators excited independently via separate coaxial input ports. Two central radiating elements for two frequency bands (L1 and L2) have got circular shapes with slits and are stacked to p...

  11. The 74MHz System on the Very Large Array

    CERN Document Server

    Kassim, N E; Erickson, W C; Perley, R A; Cotton, W D; Greisen, E W; Cohen, A S; Hicks, B; Schmitt, H R; Katz, D

    2007-01-01

    The Naval Research Laboratory and the National Radio Astronomy Observatory completed implementation of a low frequency capability on the VLA at 73.8 MHz in 1998. This frequency band offers unprecedented sensitivity (~25 mJy/beam) and resolution (~25 arcsec) for low-frequency observations. We review the hardware, the calibration and imaging strategies, comparing them to those at higher frequencies, including aspects of interference excision and wide-field imaging. Ionospheric phase fluctuations pose the major difficulty in calibrating the array. Over restricted fields of view or at times of extremely quiescent ionospheric ``weather'', an angle-invariant calibration strategy can be used. In this approach a single phase correction is devised for each antenna, typically via self-calibration. Over larger fields of view or at times of more normal ionospheric ``weather'' when the ionospheric isoplanatic patch size is smaller than the field of view, we adopt a field-based strategy in which the phase correction depend...

  12. A simple laser locking system based on a field-programmable gate array

    CERN Document Server

    Jørgensen, Nils B; Trelborg, Kristian; Wacker, Lars; Winter, Nils; Hilliard, Andrew J; Bason, Mark G; Arlt, Jan J

    2016-01-01

    Frequency stabilization of laser light is crucial in both scientific and industrial applications. Technological developments now allow analog laser stabilization systems to be replaced with digital electronics such as field-programmable gate arrays, which have recently been utilized to develop such locking systems. We have developed a frequency stabilization system based on a field-programmable gate array, with emphasis on hardware simplicity, which offers a user-friendly alternative to commercial and previous home-built solutions. Frequency modulation, lock-in detection and a proportional-integral-derivative controller are programmed on the field-programmable gate array and only minimal additional components are required to frequency stabilize a laser. The locking system is administered from a host-computer which provides comprehensive, long-distance control through a versatile interface. Various measurements were performed to characterize the system. The linewidth of the locked laser was measured to be $0.7...

  13. Comparative efficiency analysis of fiber-array and conventional beam director systems in volume turbulence.

    Science.gov (United States)

    Vorontsov, Mikhail; Filimonov, Grigory; Ovchinnikov, Vladimir; Polnau, Ernst; Lachinova, Svetlana; Weyrauch, Thomas; Mangano, Joseph

    2016-05-20

    The performance of two prominent laser beam projection system types is analyzed through wave-optics numerical simulations for various atmospheric turbulence conditions, propagation distances, and adaptive optics (AO) mitigation techniques. Comparisons are made between different configurations of both a conventional beam director (BD) using a monolithic-optics-based Cassegrain telescope and a fiber-array BD that uses an array of densely packed fiber collimators. The BD systems considered have equal input power and aperture diameters. The projected laser beam power inside the Airy size disk at the target plane is used as the performance metric. For the fiber-array system, both incoherent and coherent beam combining regimes are considered. We also present preliminary results of side-by-side atmospheric beam projection experiments over a 7-km propagation path using both the AO-enhanced beam projection system with a Cassegrain telescope and the coherent fiber-array BD composed of 21 densely packed fiber collimators. Both wave-optics numerical simulation and experimental results demonstrate that, for similar system architectures and turbulence conditions, coherent fiber-array systems are more efficient in mitigation of atmospheric turbulence effects and generation of a hit spot of the smallest possible size on a remotely located target. PMID:27411147

  14. Space Environment Testing of Photovoltaic Array Systems at NASA's Marshall Space Flight Center

    Science.gov (United States)

    Schneider, Todd A.; Vaughn, Jason A.; Wright, Kenneth H., Jr.; Phillips, Brandon S.

    2015-01-01

    CubeSats, Communication Satellites, and Outer Planet Science Satellites all share one thing in common: Mission success depends on maintaining power in the harsh space environment. For a vast majority of satellites, spacecraft power is sourced by a photovoltaic (PV) array system. Built around PV cells, the array systems also include wiring, substrates, connectors, and protection diodes. Each of these components must function properly throughout the mission in order for power production to remain at nominal levels. Failure of even one component can lead to a crippling loss of power. To help ensure PV array systems do not suffer failures on-orbit due to the space environment, NASA's Marshall Space Flight Center (MSFC) has developed a wide ranging test and evaluation capability. Key elements of this capability include: Testing: a. Ultraviolet (UV) Exposure b. Charged Particle Radiation (Electron and Proton) c. Thermal Cycling d. Plasma and Beam Environments Evaluation: a. Electrostatic Discharge (ESD) Screening b. Optical Inspection and easurement c. PV Power Output including Large Area Pulsed Solar Simulator (LAPSS) measurements This paper will describe the elements of the space environment which particularly impact PV array systems. MSFC test capabilities will be described to show how the relevant space environments can be applied to PV array systems in the laboratory. A discussion of MSFC evaluation capabilities will also be provided. The sample evaluation capabilities offer test engineers a means to quantify the effects of the space environment on their PV array system or component. Finally, examples will be shown of the effects of the space environment on actual PV array materials tested at MSFC.

  15. Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis.

    Science.gov (United States)

    Yu, Tao; Du, Yingxiang; Chen, Jiaquan; Xu, Guangfu; Yang, Ke; Zhang, Qi; Zhang, Jinjing; Du, Shuaijing; Feng, Zijie; Zhang, Yanjie

    2015-08-01

    In this paper, the use of clarithromycin lactobionate, a kind of antibiotic chiral selector, in combination with four neutral cyclodextrin derivatives (glucose-β-cyclodextrin, hydroxyethyl-β-cyclodextrin, methyl-β-cyclodextrin and hydroxypropyl-β-cyclodextrin) was reported for the first time. As a result, these dual systems gave much better resolution of nefopam (the Rs increased to 3.58, 2.72, 1.49 and 1.42, respectively) compared to the single systems. The effects of buffer pH and selector concentration on the separation of nefopam were also investigated. Additionally, some other basic drugs including metoprolol, atenolol, propranolol, bisoprolol, esmolol and ritodrine were tested for the investigation and evaluation of the enantiorecognition capability of the four dual systems. As expected, the synergistic effect was observed in four systems. Different results of these dual systems were also summarized. PMID:26097042

  16. Apparatus for electrophoresis separation

    Science.gov (United States)

    Anderson, Norman L.

    1978-01-01

    An apparatus is disclosed for simultaneously performing electrophoresis separations on a plurality of slab gels containing samples of protein, protein subunits or nucleic acids. A reservoir of buffer solution is divided into three compartments by two parallel partitions having vertical slots spaced along their length. A sheet of flexible, electrically insulative material is attached to each partition and is provided with vertical slits aligned with the slots. Slab-gel holders are received within the slots with the flexible material folded outwardly as flaps from the slits to overlay portions of the holder surfaces and thereby act as electrical and liquid seals. An elongated, spaghetti-like gel containing a sample of specimen that was previously separated by isoelectric focusing techniques is vertically positioned along a marginal edge portion of the slab gel. On application of an electrical potential between the two outer chambers of buffer solution, a second dimensional electrophoresis separation in accordance with molecular weight occurs as the specimen molecules migrate across the slab gel.

  17. A camac based data acquisition system for flat-panel image array readout

    International Nuclear Information System (INIS)

    A readout system has been developed to facilitate the digitization and subsequent display of image data from two-dimensional, pixellated, flat-panel, amorphous silicon imaging arrays. These arrays have been designed specifically for medical x-ray imaging applications. The readout system is based on hardware and software developed for various experiments at CERN and Fermi National Accelerator Laboratory. Additional analog signal processing and digital control electronics were constructed specifically for this application. The authors report on the form of the resulting data acquisition system, discuss aspects of its performance, and consider the compromises which were involved in its design

  18. Highly sensitive trivalent copper chelate–luminol chemiluminescence system for capillary electrophoresis chiral separation and determination of ofloxacin enantiomers in urine samples

    Directory of Open Access Journals (Sweden)

    Hao-Yue Xie

    2014-12-01

    Full Text Available A simple, fast and sensitive capillary electrophoresis (CE strategy combined with chemiluminescence (CL detection for analysis of ofloxacin (OF enantiomers was established in the present work. Sulfonated β-cyclodextrin (β-CD was used as the chiral additive being added into the running buffer of luminol–diperiodatocuprate (III (K5[Cu(HIO62], DPC chemiluminescence system. Under the optimum conditions, the proposed method was successfully applied to separation and analysis of OF enantiomers with the detection limits (S/N=3 of 8.0 nM and 7.0 nM for levofloxacin and dextrofloxacin, respectively. The linear ranges were both 0.010–100 μM. The method was utilized for analyzing OF in urine; the results obtained were satisfactory and recoveries were 89.5–110.8%, which demonstrated the reliability of this method. This approach can also be further extended to analyze different commercial OF medicines.

  19. Development of new chiral ligand exchange capillary electrophoresis system with amino acid ionic liquids ligands and its application in studying the kinetics of L-amino acid oxidase

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Bingbing [Beijing National Laboratory for Molecular Sciences, Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); College of Food Sciences and Engineering, Shandong Agricultural University, Tai’an, Shandong 271018 (China); Mu, Xiaoyu [Beijing National Laboratory for Molecular Sciences, Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Qi, Li, E-mail: qili@iccas.ac.cn [Beijing National Laboratory for Molecular Sciences, Key Lab of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-04-01

    Highlights: • Novel amino acid ionic liquids with pyridinium as cations and L-lysine as anion were synthesized. • These synthesized AAILs have been explored as the ligands coordinated with Zn(II) in CLE-CE system. • The developed CLE-CE method could be used for the enantioseparation of Dns-D, L-amino acids. • The kinetic contents of L-amino acid oxidase were investigated with the proposed CLE-CE system. - Abstract: New kinds of amino acid ionic liquids (AAILs) with pyridinium as cations and L-lysine (L-Lys) as anion have been developed as the available chiral ligands coordinated with Zn(II) in chiral ligand-exchange capillary electrophoresis (CLE-CE). Four kinds of AAILs, including [1-ethylpyridinium][L-lysine], 1-butylpyridinium][L-lysine], [1-hexylpyridinium][L-lysine] and 1-[octylpyridinium][L-lysine], were successfully synthesized and characterized by nuclear magnetic resonance and mass spectrometry. Compared with other AAILs, the best chiral separation of Dns-D, L-amino acids could be achieved when [1-ethylpyridinium][L-lysine] was chosen as the chiral ligand. It has been found that after investigating the influence of key factors on the separation efficiency, such as pH of buffer solution, the ratio of Zn(II) to ligand and complex concentration, eight pairs of Dns-D, L-AAs enantiomers could be baseline separated and three pairs were partly separated under the optimum conditions. The proposed CLE-CE method also exhibited favorable quantitative analysis property of Dns-D, L-Met with good linearity (r{sup 2} = 0.998) and favorable repeatability (RSD ≤ 1.5%). Furthermore, the CLE-CE system was applied in investigating the kinetic contents of L-amino acid oxidase, which implied that the proposed system has the potential in studying the enzymatic reaction mechanism.

  20. The design of a DAQ system for a GEM imaging detector based on FET array readout

    International Nuclear Information System (INIS)

    A data acquisition system was designed for a GEM imaging detector, which is readout by a FET switch array and can be used in real-time imaging. By using some advanced technologies, like FPGA and MCU, the designed DAQ system succeeds in multi-channel real-time readout with high-accuracy and high universality. (authors)

  1. Recombinant drugs-on-a-chip: The usage of capillary electrophoresis and trends in miniaturized systems - A review.

    Science.gov (United States)

    Morbioli, Giorgio Gianini; Mazzu-Nascimento, Thiago; Aquino, Adriano; Cervantes, Cesar; Carrilho, Emanuel

    2016-09-01

    We present here a critical review covering conventional analytical tools of recombinant drug analysis and discuss their evolution towards miniaturized systems foreseeing a possible unique recombinant drug-on-a-chip device. Recombinant protein drugs and/or pro-drug analysis require sensitive and reproducible analytical techniques for quality control to ensure safety and efficacy of drugs according to regulatory agencies. The versatility of miniaturized systems combined with their low-cost could become a major trend in recombinant drugs and bioprocess analysis. Miniaturized systems are capable of performing conventional analytical and proteomic tasks, allowing for interfaces with other powerful techniques, such as mass spectrometry. Microdevices can be applied during the different stages of recombinant drug processing, such as gene isolation, DNA amplification, cell culture, protein expression, protein separation, and analysis. In addition, organs-on-chips have appeared as a viable alternative to testing biodrug pharmacokinetics and pharmacodynamics, demonstrating the capabilities of the miniaturized systems. The integration of individual established microfluidic operations and analytical tools in a single device is a challenge to be overcome to achieve a unique recombinant drug-on-a-chip device. PMID:27543014

  2. A leading edge heating array and a flat surface heating array: Final design. [for testing the thermal protection system of the space shuttle

    Science.gov (United States)

    1975-01-01

    A heating array is described for testing full-scale sections of the leading edge and lower fuselage surfaces of the shuttle. The heating array was designed to provide a tool for development and acceptance testing of leading edge segments and large flat sections of the main body thermal protection system. The array was designed using a variable length module concept to meet test requirements using interchangeable components from one test configuration in another configuration. Heat generating modules and heat absorbing modules were employed to achieve the thermal gradient around the leading edge. A support was developed to hold the modules to form an envelope around a variety of leading edges; to supply coolant to each module; the support structure and to hold the modules in the flat surface heater configuration. An optical pyrometer system mounted within the array was designed to monitor specimen surface temperatures without altering the test article's surface.

  3. A Systematic Method of Interconnection Optimization for Dense-Array Concentrator Photovoltaic System

    Science.gov (United States)

    Siaw, Fei-Lu

    2013-01-01

    This paper presents a new systematic approach to analyze all possible array configurations in order to determine the most optimal dense-array configuration for concentrator photovoltaic (CPV) systems. The proposed method is fast, simple, reasonably accurate, and very useful as a preliminary study before constructing a dense-array CPV panel. Using measured flux distribution data, each CPV cells' voltage and current values at three critical points which are at short-circuit, open-circuit, and maximum power point are determined. From there, an algorithm groups the cells into basic modules. The next step is I-V curve prediction, to find the maximum output power of each array configuration. As a case study, twenty different I-V predictions are made for a prototype of nonimaging planar concentrator, and the array configuration that yields the highest output power is determined. The result is then verified by assembling and testing of an actual dense-array on the prototype. It was found that the I-V curve closely resembles simulated I-V prediction, and measured maximum output power varies by only 1.34%. PMID:24453823

  4. A Systematic Method of Interconnection Optimization for Dense-Array Concentrator Photovoltaic System

    Directory of Open Access Journals (Sweden)

    Fei-Lu Siaw

    2013-01-01

    Full Text Available This paper presents a new systematic approach to analyze all possible array configurations in order to determine the most optimal dense-array configuration for concentrator photovoltaic (CPV systems. The proposed method is fast, simple, reasonably accurate, and very useful as a preliminary study before constructing a dense-array CPV panel. Using measured flux distribution data, each CPV cells’ voltage and current values at three critical points which are at short-circuit, open-circuit, and maximum power point are determined. From there, an algorithm groups the cells into basic modules. The next step is I-V curve prediction, to find the maximum output power of each array configuration. As a case study, twenty different I-V predictions are made for a prototype of nonimaging planar concentrator, and the array configuration that yields the highest output power is determined. The result is then verified by assembling and testing of an actual dense-array on the prototype. It was found that the I-V curve closely resembles simulated I-V prediction, and measured maximum output power varies by only 1.34%.

  5. Efficient Analysis of Systems Biology Markup Language Models of Cellular Populations Using Arrays.

    Science.gov (United States)

    Watanabe, Leandro; Myers, Chris J

    2016-08-19

    The Systems Biology Markup Language (SBML) has been widely used for modeling biological systems. Although SBML has been successful in representing a wide variety of biochemical models, the core standard lacks the structure for representing large complex regular systems in a standard way, such as whole-cell and cellular population models. These models require a large number of variables to represent certain aspects of these types of models, such as the chromosome in the whole-cell model and the many identical cell models in a cellular population. While SBML core is not designed to handle these types of models efficiently, the proposed SBML arrays package can represent such regular structures more easily. However, in order to take full advantage of the package, analysis needs to be aware of the arrays structure. When expanding the array constructs within a model, some of the advantages of using arrays are lost. This paper describes a more efficient way to simulate arrayed models. To illustrate the proposed method, this paper uses a population of repressilator and genetic toggle switch circuits as examples. Results show that there are memory benefits using this approach with a modest cost in runtime. PMID:26912276

  6. The High-Level Interface Definitions in the ASTRI/CTA Mini Array Software System (MASS)

    Science.gov (United States)

    Conforti, V.; Tosti, G.; Schwarz, J.; Bruno, P.; Cefal‘A, M.; Paola, A. D.; Gianotti, F.; Grillo, A.; Russo, F.; Tanci, C.; Testa, V.; Antonelli, L. A.; Canestrari, R.; Catalano, O.; Fiorini, M.; Gallozzi, S.; Giro, E.; Palombara, N. L.; Leto, G.; Maccarone, M. C.; Pareschi, G.; Stringhetti, L.; Trifoglio, M.; Vercellone, S.; Astri Collaboration; Cta Consortium

    2015-09-01

    ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) is a Flagship Project funded by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. Within this framework, INAF is currently developing an end-to-end prototype, named ASTRI SST-2M, of a Small Size Dual-Mirror Telescope for the Cherenkov Telescope Array, CTA. A second goal of the project is the realization of the ASTRI/CTA mini-array, which will be composed of seven SST-2M telescopes placed at the CTA Southern Site. The ASTRI Mini Array Software System (MASS) is designed to support the ASTRI/CTA mini-array operations. MASS is being built on top of the ALMA Common Software (ACS) framework, which provides support for the implementation of distributed data acquisition and control systems, and functionality for log and alarm management, message driven communication and hardware devices management. The first version of the MASS system, which will comply with the CTA requirements and guidelines, will be tested on the ASTRI SST-2M prototype. In this contribution we present the interface definitions of the MASS high level components in charge of the ASTRI SST-2M observation scheduling, telescope control and monitoring, and data taking. Particular emphasis is given to their potential reuse for the ASTRI/CTA mini-array.

  7. Space Environment Testing of Photovoltaic Array Systems at NASA's Marshall Space Flight Center

    Science.gov (United States)

    Phillips, Brandon S.; Schneider, Todd A.; Vaughn, Jason A.; Wright, Kenneth H., Jr.

    2015-01-01

    To successfully operate a photovoltaic (PV) array system in space requires planning and testing to account for the effects of the space environment. It is critical to understand space environment interactions not only on the PV components, but also the array substrate materials, wiring harnesses, connectors, and protection circuitry (e.g. blocking diodes). Key elements of the space environment which must be accounted for in a PV system design include: Solar Photon Radiation, Charged Particle Radiation, Plasma, and Thermal Cycling. While solar photon radiation is central to generating power in PV systems, the complete spectrum includes short wavelength ultraviolet components, which photo-ionize materials, as well as long wavelength infrared which heat materials. High energy electron radiation has been demonstrated to significantly reduce the output power of III-V type PV cells; and proton radiation damages material surfaces - often impacting coverglasses and antireflective coatings. Plasma environments influence electrostatic charging of PV array materials, and must be understood to ensure that long duration arcs do not form and potentially destroy PV cells. Thermal cycling impacts all components on a PV array by inducing stresses due to thermal expansion and contraction. Given such demanding environments, and the complexity of structures and materials that form a PV array system, mission success can only be ensured through realistic testing in the laboratory. NASA's Marshall Space Flight Center has developed a broad space environment test capability to allow PV array designers and manufacturers to verify their system's integrity and avoid costly on-orbit failures. The Marshall Space Flight Center test capabilities are available to government, commercial, and university customers. Test solutions are tailored to meet the customer's needs, and can include performance assessments, such as flash testing in the case of PV cells.

  8. High Voltage Solar Array Arc Testing for a Direct Drive Hall Effect Thruster System

    Science.gov (United States)

    Schneider, Todd; Carruth, M. R., Jr.; Vaughn, J. A.; Jongeward, G. A.; Mikellides, I. G.; Ferguson, D.; Kerslake, T. W.; Peterson, T.; Snyder, D.; Hoskins, A.

    2004-01-01

    The deleterious effects of spacecraft charging are well known, particularly when the charging leads to arc events. The damage that results from arcing can severely reduce system lifetime and even cause critical system failures. On a primary spacecraft system such as a solar array, there is very little tolerance for arcing. Motivated by these concerns, an experimental investigation was undertaken to determine arc thresholds for a high voltage (200-500 V) solar array in a plasma environment. The investigation was in support of a NASA program to develop a Direct Drive Hall-Effect Thruster (D2HET) system. By directly coupling the solar array to a Hall-effect thruster, the D2HET program seeks to reduce mass, cost and complexity commonly associated with the power processing in conventional power systems. In the investigation, multiple solar array technologies and configurations were tested. The cell samples were biased to a negative voltage, with an applied potential difference between them, to imitate possible scenarios in solar array strings that could lead to damaging arcs. The samples were tested in an environment that emulated a low-energy, HET-induced plasma. Short duration trigger arcs as well as long duration sustained arcs were generated. Typical current and voltage waveforms associated with the arc events are presented. Arc thresholds are also defined in terms of voltage, current and power. The data will be used to propose a new, high-voltage (greater than 300 V) solar array design for which the likelihood of damage from arcing is minimal.

  9. DNA Sequencing Using capillary Electrophoresis

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Barry Karger

    2011-05-09

    The overall goal of this program was to develop capillary electrophoresis as the tool to be used to sequence for the first time the Human Genome. Our program was part of the Human Genome Project. In this work, we were highly successful and the replaceable polymer we developed, linear polyacrylamide, was used by the DOE sequencing lab in California to sequence a significant portion of the human genome using the MegaBase multiple capillary array electrophoresis instrument. In this final report, we summarize our efforts and success. We began our work by separating by capillary electrophoresis double strand oligonucleotides using cross-linked polyacrylamide gels in fused silica capillaries. This work showed the potential of the methodology. However, preparation of such cross-linked gel capillaries was difficult with poor reproducibility, and even more important, the columns were not very stable. We improved stability by using non-cross linked linear polyacrylamide. Here, the entangled linear chains could move when osmotic pressure (e.g. sample injection) was imposed on the polymer matrix. This relaxation of the polymer dissipated the stress in the column. Our next advance was to use significantly lower concentrations of the linear polyacrylamide that the polymer could be automatically blown out after each run and replaced with fresh linear polymer solution. In this way, a new column was available for each analytical run. Finally, while testing many linear polymers, we selected linear polyacrylamide as the best matrix as it was the most hydrophilic polymer available. Under our DOE program, we demonstrated initially the success of the linear polyacrylamide to separate double strand DNA. We note that the method is used even today to assay purity of double stranded DNA fragments. Our focus, of course, was on the separation of single stranded DNA for sequencing purposes. In one paper, we demonstrated the success of our approach in sequencing up to 500 bases. Other

  10. C-MOS array design techniques: SUMC multiprocessor system study

    Science.gov (United States)

    Clapp, W. A.; Helbig, W. A.; Merriam, A. S.

    1972-01-01

    The current capabilities of LSI techniques for speed and reliability, plus the possibilities of assembling large configurations of LSI logic and storage elements, have demanded the study of multiprocessors and multiprocessing techniques, problems, and potentialities. Evaluated are three previous systems studies for a space ultrareliable modular computer multiprocessing system, and a new multiprocessing system is proposed that is flexibly configured with up to four central processors, four 1/0 processors, and 16 main memory units, plus auxiliary memory and peripheral devices. This multiprocessor system features a multilevel interrupt, qualified S/360 compatibility for ground-based generation of programs, virtual memory management of a storage hierarchy through 1/0 processors, and multiport access to multiple and shared memory units.

  11. Tuning of Kilopixel Transition Edge Sensor Bolometer Arrays with a Digital Frequency Multiplexed Readout System

    CERN Document Server

    MacDermid, K; Aubin, F; Bissonnette, E; Dobbs, M; Hubmayr, J; Smecher, G; Warraich, S

    2009-01-01

    A digital frequency multiplexing (DfMUX) system has been developed and used to tune large arrays of transition edge sensor (TES) bolometers read out with SQUID arrays for mm-wavelength cosmology telescopes. The DfMUX system multiplexes the input bias voltages and output currents for several bolometers on a single set of cryogenic wires. Multiplexing reduces the heat load on the camera's sub-Kelvin cryogenic detector stage. In this paper we describe the algorithms and software used to set up and optimize the operation of the bolometric camera. The algorithms are implemented on soft processors embedded within FPGA devices operating on each backend readout board. The result is a fully parallelized implementation for which the setup time is independent of the array size.

  12. A fully automated in vitro diagnostic system based on magnetic tunnel junction arrays and superparamagnetic particles

    Science.gov (United States)

    Lian, Jie; Chen, Si; Qiu, Yuqin; Zhang, Suohui; Shi, Stone; Gao, Yunhua

    2012-04-01

    A fully automated in vitro diagnostic (IVD) system for diagnosing acute myocardial infarction was developed using high sensitivity MTJ array as sensors and nano-magnetic particles as tags. On the chip is an array of 12 × 106 MTJ devices integrated onto a 3 metal layer CMOS circuit. The array is divided into 48 detection areas, therefore 48 different types of bio targets can be analyzed simultaneously if needed. The chip is assembled with a micro-fluidic cartridge which contains all the reagents necessary for completing the assaying process. Integrated with electrical, mechanical and micro-fluidic pumping devices and with the reaction protocol programed in a microprocessor, the system only requires a simple one-step analyte application procedure to operate and yields results of the three major AMI bio-markers (cTnI, MYO, CK-MB) in 15 mins.

  13. Analysis and design of coupled-oscillator arrays for microwave systems

    Science.gov (United States)

    Moussounda, Renaud

    The concept of synchronized nonlinear coupled oscillators is applied to microwave and antenna engineering for the analysis and design of wireless communication and sensing systems operating at the microwave and/or millimeter (mm)-wave frequencies. The significance of such approach is justified from the potential gain in efficiency, weight, cost and functionality although technical challenges stand in the way. Unlike typical phased array systems, which are currently used to construct such systems, coupled-oscillator systems present additional challenges that mainly arise from maintaining stability and synchronization as the the coupled nonlinear system is operated. Linear systems do not present such stability issues and are consequently faster since they do not rely on any gradual synchronization mechanism in order to function. However, at significantly higher frequencies in the quasi-optical domain, coupled-oscillator systems can make up for the speed difference and present significant efficiency advantages over typical phased array architectures. In addition, coupled nonlinear systems possess inherent analog properties that can be used for a multitude of functions. This dissertation advances the topic of coupled-oscillator arrays by 1) developing an alternative set of techniques for designing the oscillating unit cells called active integrated antennas (AIAs) at microwave or mm-wave frequencies, 2) developing a more accurate description of the dynamics of the array, 3) developing and implementing a new topology for a coupling network that is able to extend stability, 4) implementing a fully non-reciprocally coupled array able to produce large scan angle without loss of stability, 5) proposing an architecture based on a single phase-locked loop (PLL) and containing a self-calibration mechanism, and finally 6) implementing a phase-boosting mechanism using simple circuits to amplify the phase difference between adjacent radiating antennas in order to increase

  14. A capillary electrophoresis system with dual capacitively coupled contactless conductivity detection and electrospray ionization tandem mass spectrometry.

    Science.gov (United States)

    Francisco, Kelliton José Mendonça; do Lago, Claudimir Lucio

    2016-07-01

    A commercial system that is comprised of a CE coupled to an ESI triple quadrupole mass spectrometer was equipped with two capacitively coupled contactless conductivity detectors (C(4) Ds). The first C(4) D was positioned inside the original cartridge, and the second C(4) D was positioned as close as possible to the ESI probe entrance by using a 3D-printed support. The C(4) Ds electropherograms were matched to the ESI-MS electropherogram by correcting their timescales by the factor LT /LD , where LT and LD are the total capillary length and the length until the C(4) D, respectively. A general approach for method development supporting the simultaneous conductivity and MS detection is discussed, while application examples are introduced. These examples include the use of C(4) D as a simple device that dismiss the use of an EOF marker, a low-selectivity detector that continuously provide information about unexpected features of the sample, and even a detector that can be more sensitive than ESI-MS. The C(4) D used in this setup proved to have a smaller contribution to the peak broadening than ESI-MS, which allowed that a C(4) D, positioned at 12 cm from the inlet of an 80-cm-long capillary, could be used to foresee position and shape of the peaks being formed 6.8 times slower at the ESI-MS electropherogram. PMID:27027468

  15. Performance study of solar cell arrays based on a Trough Concentrating Photovoltaic/Thermal system

    International Nuclear Information System (INIS)

    Highlights: → The performances of solar cell arrays based on a Trough Concentrating Photovoltaic/Thermal (TCPV/T) system have been studied. → The optimum concentration ratios for the single crystalline silicon cell, the Super cells and the GaAs cells were studied by experiments. → The influences between the solar cell's performance and the series resistances, the working temperature, solar irradiation intensity were explored. - Abstract: The performances of solar cell arrays based on a Trough Concentrating Photovoltaic/Thermal (TCPV/T) system have been studied via both experiment and theoretical calculation. The I-V characteristics of the solar cell arrays and the output performances of the TCPV/T system demonstrated that among the investigated four types of solar cell arrays, the triple junction GaAs cells possessed good performance characteristics and the polysilicon cells exhibited poor performance characteristics under concentrating conditions. The optimum concentration ratios for the single crystalline silicon cell, the Super cells and the GaAs cells were also studied by experiments. The optimum concentration ratios for the single crystalline silicon cells and Super cells were 4.23 and 8.46 respectively, and the triple junction GaAs cells could work well at higher concentration ratio. Besides, some theoretical calculations and experiments were performed to explore the influences of the series resistances and the working temperature. When the series resistances Rs changed from 0 Ω to 1 Ω, the maximum power Pm of the single crystalline silicon, the polycrystalline silicon, the Super cell and the GaAs cell arrays decreased by 67.78%, 74.93%, 77.30% and 58.07% respectively. When the cell temperature increased by 1 K, the short circuit current of the four types of solar cell arrays decreased by 0.11818 A, 0.05364 A, 0.01387 A and 0.00215 A respectively. The research results demonstrated that the output performance of the solar cell arrays with lower series

  16. 2D Active Antenna Array Design for FD-MIMO System and Antenna Virtualization Techniques

    Directory of Open Access Journals (Sweden)

    Ioannis Tzanidis

    2015-01-01

    Full Text Available Full dimension MIMO (FD-MIMO is one of the key technologies presently studied in the 3GPP for the next generation long-term evolution advanced (LTE-A systems. By incorporating FD-MIMO into LTE/LTE-A systems, it is expected that system throughput will be drastically improved beyond what is possible in conventional LTE systems. This paper presets details on the 2D active antenna array design for FD-MIMO systems supporting 32 antenna elements. The FD-MIMO system allows for dynamic and adaptive precoding to be performed jointly across all antennas thus achieving more directional transmissions in the azimuth and elevation domains simultaneously, to a larger number of users. Finally, we discuss 2D antenna array port virtualization techniques for creating beams with wide coverage, necessary for broadcasting signals to all users within a sector, such as the CRS (Common Reference Signal.

  17. DNA DAMAGE QUANTITATION BY ALKALINE GEL ELECTROPHORESIS.

    Energy Technology Data Exchange (ETDEWEB)

    SUTHERLAND,B.M.; BENNETT,P.V.; SUTHERLAND, J.C.

    2004-03-24

    Physical and chemical agents in the environment, those used in clinical applications, or encountered during recreational exposures to sunlight, induce damages in DNA. Understanding the biological impact of these agents requires quantitation of the levels of such damages in laboratory test systems as well as in field or clinical samples. Alkaline gel electrophoresis provides a sensitive (down to {approx} a few lesions/5Mb), rapid method of direct quantitation of a wide variety of DNA damages in nanogram quantities of non-radioactive DNAs from laboratory, field, or clinical specimens, including higher plants and animals. This method stems from velocity sedimentation studies of DNA populations, and from the simple methods of agarose gel electrophoresis. Our laboratories have developed quantitative agarose gel methods, analytical descriptions of DNA migration during electrophoresis on agarose gels (1-6), and electronic imaging for accurate determinations of DNA mass (7-9). Although all these components improve sensitivity and throughput of large numbers of samples (7,8,10), a simple version using only standard molecular biology equipment allows routine analysis of DNA damages at moderate frequencies. We present here a description of the methods, as well as a brief description of the underlying principles, required for a simplified approach to quantitation of DNA damages by alkaline gel electrophoresis.

  18. The design and application of large area intensive lens array focal spots measurement system

    Science.gov (United States)

    Chen, Bingzhen; Yao, Shun; Yang, Guanghui; Dai, Mingchong; Wang, Zhiyong

    2014-12-01

    Concentrating Photovoltaic (CPV) modules are getting thinner and using smaller cells now days. Correspondingly, large area intensive lens arrays with smaller unit dimension and shorter focal length are wanted. However, the size and power center of lens array focal spots usually differ from the design value and are hard to measure, especially under large area situation. It is because the machining error and deformation of material of the lens array are hard to simulate in the optical design process. Thus the alignment error between solar cells and focal spots in the module assembly process will be hard to control. Under this kind of situation, the efficiency of CPV module with thinner body and smaller cells is much lower than expected. In this paper, a design of large area lens array focal spots automatic measurement system is presented, as well as its prototype application results. In this system, a four-channel parallel light path and its corresponding image capture and process modules are designed. These modules can simulate focal spots under sunlight and have the spots image captured and processed using charge coupled devices and certain gray level algorithm. Thus the important information of focal spots such as spot size and location will be exported. Motion control module based on grating scale signal and interval measurement method are also employed in this system in order to get test results with high speed and high precision on large area lens array no less than 1m×0.8m. The repeatability of the system prototype measurement is +/-10μm with a velocity of 90 spot/min. Compared to the original module assembled using coordinates from optical design, modules assembled using data exported from the prototype is 18% higher in output power, reaching a conversion efficiency of over 31%. This system and its design can be used in the focal spot measurement of planoconvex lens array and Fresnel lens array, as well as other kinds of large area lens array application

  19. A position sensitive detector system consisting of an array of mini-proportional counters

    International Nuclear Information System (INIS)

    A new position sensitive detector system has been developed for the Hard X-ray Imaging Spectrometer launched aboard the NASA Solar Maximum Mission. The instrument operates in the energy range 3.5 - 30 keV. The Xe-gas filled detector system consists of a photon absorption compartment and an array of 900 mini-proportional counters. The detector lay-out and the system performance are described

  20. Virtual 3D interactive system with embedded multiwavelength optical sensor array and sequential devices

    Science.gov (United States)

    Wang, Guo-Zhen; Huang, Yi-Pai; Hu, Kuo-Jui

    2012-06-01

    We proposed a virtual 3D-touch system by bare finger, which can detect the 3-axis (x, y, z) information of finger. This system has multi-wavelength optical sensor array embedded on the backplane of TFT panel and sequentail devices on the border of TFT panel. We had developed reflecting mode which can be worked by bare finger for the 3D interaction. A 4-inch mobile 3D-LCD with this proposed system was successfully been demonstrated already.

  1. Development of an Efficient Design Technique for the Optimisation of Mooring Systems for Wave Energy Arrays

    OpenAIRE

    Kirrane, P.; Fabricius, P; Morvan, R.

    2011-01-01

    Research, funded by the Marine Institute, was carried out on mooring systems for wave energy arrays. An outline of the research results and outcomes are presented in this report. The objectives of the research were to: review the wave energy industry and define design parameters; establish a comprehensive set of design curves to facilitate the selection of a preliminary mooring system; develop trends in system response from the evaluation of a broad range of Wave Energy Converter (WEC) specif...

  2. Fast extraction control system based on field programmable gate array

    International Nuclear Information System (INIS)

    In order to realize the fast extraction of beam from the HIRFL-CSR (the Heavy Ion Research Facility at Lanzhou-Cooler Storage Ring) main ring, we adopt an extraction system based on FPGA technique. The digital multiplication of clock frequency method is employed in the design of FPGA, to accurately control the charging time and discharging time of Kicker magnet during a high-frequency period. Test results show that the time accuracy of the system reaches 5 ns for beam locating and beam adjusting in the storage ring. At the high-frequency of 1.4 MHz, triggering Kicker can be realized with phase accuracy of 2.5 degree in the scale of 0 to 360 degree. (authors)

  3. A compact and low-cost miniaturized analysis system composed of microchip electrophoresis and chemiluminescence detection manipulated by a simple subatmospheric pressure fluid-driven device.

    Science.gov (United States)

    Wang, Xiuzhong; Yin, Xuefeng; Cheng, Heyong; Shen, Hong

    2010-07-01

    A portable and low-cost miniaturized analysis system was proposed, in which microchip electrophoresis (MCE) and chemiluminescence (CL) were used as the separation and detection units, respectively. A porous monolithic plug was created in the separation channel of the microchip as a select valve, which prevented the pressure-driven CL reagents flowing back into the separation channel but allowed electrophoretic migration along the separation channel. The sensitivity was greatly enhanced by improving the mixing efficiency using a spiral detection channel with an increased length facing the photomultiplier tube (PMT). Peak width could be significantly reduced by increasing the flow rate of CL reagents. Putting grounding electrode before the detection channel significantly improved the reproducibility. A simple and compact subatmospheric pressure fluid-driven device was developed for manipulating the whole analytical process, including variable-volume sample loading, electrophoretic separation and CL reagents transportation. All miniaturized components for constructing a portable MCE-CL system are commercially available. This approach considerably simplified the operation and equipments for constructing an efficient MCE-CL system. Nine metal cations, such as Cr(III), Co(II), Cu(II), Ni(II), Au(III), Mn(II), Zn(II), Pt(II), Pb(II) were successfully separated within 200 s. Migration time precisions ranging from 0.39% for Cr(III) to 2.1% for Cu(II) were obtained for ten consecutive determinations with peak height precisions from 1.67% for Co(II) to 5.73% for Pb(II). Detection limits ranging from 7.5 x 10(-11) mol L(-1) for Co(II) to 8.3 x 10(-9) mol L(-1) for Pb(II) were achieved, which were about three orders lower than the present MCE-CL system. It has been applied for the determination of metals in tea. The results with the recoveries from 97.0% to 102.3% proved that the proposed MCE-CL system offers a number of benefits including miniaturization, high sensitivity and

  4. Implementation of USP antibody standard for system suitability in capillary electrophoresis sodium dodecyl sulfate (CE-SDS) for release and stability methods.

    Science.gov (United States)

    Esterman, Abbie L; Katiyar, Amit; Krishnamurthy, Girija

    2016-09-01

    Capillary electrophoresis sodium dodecyl sulfate (CE-SDS) is widely used for purity analysis of monoclonal antibody therapeutics for release and stability to demonstrate product consistency and shelf life during the manufacturing and life cycle of the product. CE-SDS method development is focused on exploring the method capability to provide the information about the product purity and product related degradants (fragmentation, aggregation etc.). In order to establish the functionality of the instrumentation, software, and sample preparation; system suitability criteria need to be defined for analytical methods using a well characterized reference standard run under the same protocol and analysis as the test articles. Typically the reference standard is produced using a manufacturing process representative of the clinical material. The qualification, control, and maintenance of in-house reference standards are established through rigorous quality and regulatory guidelines. The U.S. Pharmacopeia (USP) has developed a monoclonal IgG System Suitability Reference Standard to be utilized for assessment of system suitability in CE-SDS methods. In this communication, we evaluate the system suitability acceptance criteria performance of the USP IgG standard using two methods, the recommended USP protocol provided in monograph and a molecule specific Bristol-Myers Squibb (BMS) CE-SDS method. The results from USP IgG standard were compared with two in-house monoclonal antibody reference standards. The data suggest that the USP CE-SDS method may not be suitable for CE-SDS analysis for release and stability of monoclonal antibody therapeutics due to the high level of method induced partial reduction observed for all molecules tested. This high level of fragmentation observed utilizing the USP method will result in reporting lower purity levels, which will impact the overall quality assessment of the molecule. The system suitability criteria recommended by the USP method can be

  5. 10-channel fiber array fabrication technique for parallel optical coherence tomography system

    Science.gov (United States)

    Arauz, Lina J.; Luo, Yuan; Castillo, Jose E.; Kostuk, Raymond K.; Barton, Jennifer

    2007-02-01

    Optical Coherence Tomography (OCT) shows great promise for low intrusive biomedical imaging applications. A parallel OCT system is a novel technique that replaces mechanical transverse scanning with electronic scanning. This will reduce the time required to acquire image data. In this system an array of small diameter fibers is required to obtain an image in the transverse direction. Each fiber in the array is configured in an interferometer and is used to image one pixel in the transverse direction. In this paper we describe a technique to package 15μm diameter fibers on a siliconsilica substrate to be used in a 2mm endoscopic probe tip. Single mode fibers are etched to reduce the cladding diameter from 125μm to 15μm. Etched fibers are placed into a 4mm by 150μm trench in a silicon-silica substrate and secured with UV glue. Active alignment was used to simplify the lay out of the fibers and minimize unwanted horizontal displacement of the fibers. A 10-channel fiber array was built, tested and later incorporated into a parallel optical coherence system. This paper describes the packaging, testing, and operation of the array in a parallel OCT system.

  6. High-Gain Textile Antenna Array System for Off-Body Communication

    Directory of Open Access Journals (Sweden)

    Maria Lucia Scarpello

    2012-01-01

    Full Text Available A novel high-gain textile antenna array system, fully integrated into a rescue-worker’s vest and operating in the Industrial, Scientific, and Medical wireless band (2.4–2.4835 GHz, is presented. The system comprises an array consisting of four tip-truncated equilateral triangular microstrip patch antennas (ETMPAs, a power divider, line stretchers, and coaxial cables. The array is vertically positioned on the human torso to produce a narrow beam in elevation, as such reducing fading and allowing to steer the maximum gain in a small angular sector centered around the broadside direction. To allow simple low-cost beam steering, we specifically minimize mutual coupling by using a relative large distance between the patches and by selecting the ETMPA element as the most suited topology from three potential patch geometries. Moreover, we investigate the stability of return loss and mutual coupling characteristics under different relative humidity conditions, when bending the array, when placing the system on-body, and when covering it by different textile layers. Reflection coefficient and gain patterns are simulated and measured for the antenna system in free space and placed on the human body.

  7. How biological (fish) noise affects the performance of shallow water passive array system

    Digital Repository Service at National Institute of Oceanography (India)

    Fernandes, W.A.; Chakraborty, B.; Haris, K.; Vijayakumar, K.; Sundar, D.; Luis, R.A.A.; Mahanty, M.M.; Latha, G.

    Passive acoustic data off Grand Island, Goa were acquired using a single wideband hydrophone system deployed at the water depth of ~20.5 m during the month of April, 2014. The 4- elements hydrophone array with an aperture of 1.5 m having design...

  8. Validation and Verification of the Field Programmable Gate Array Based Charge Collection Efficiency Measurement System

    International Nuclear Information System (INIS)

    Based on field programmable gate array (FPGA), we propose a QA/ QC test procedures to validate and verify the operation and the data obtained from newly developed charge collection efficiency (CCE) measurement system. The QA/ QC test procedures were able to detected by a normal test run whilst the operation of the amplifier; counter; and timer were validated and verified. (author)

  9. Error Analysis of Two Round Plane Circular Sensors Arrays based Acoustic Positioning System

    Directory of Open Access Journals (Sweden)

    Lin Wu Song

    2015-01-01

    Full Text Available The passive acoustic locating technology is used widely in many fields. The lower locating accuracy of long distance targets location is one of the key problems that always affect its applications. In order to locate the long distance acoustic target passively, a scheme of two round plane circular arrays is presented. Each array is equate to a Vector-Sensor, could locate the direction of the target. The error source of the system is analyzed in detail. The effects of errors on the accuracy of the location are given, and then the simulation is made.

  10. Hybrid electron cyclotron emission imaging array system for Texas experimental tokamak upgrade

    International Nuclear Information System (INIS)

    A novel wide bandwidth, low-cost, 20 channel hybrid Schottky diode mixer array-based imaging system has been developed, tested and implemented for electron cyclotron emission diagnostics on the Texas experimental tokamak upgrade (TEXT-U). The array has been successfully utilized to measure 1D and 2D electron temperature profiles, to study sawteeth and magnetohydrodynamic phenomena, and to make measurements of the poloidal/radial correlation lengths and wave-number spectra of electron temperature fluctuations. Fabrication and laboratory characterization results are presented, together with details and test results from the actual implementation on TEXT-U. copyright 1997 American Institute of Physics

  11. Inspection system for welded tubular joint based on ultrasonic phased array

    Institute of Scientific and Technical Information of China (English)

    Hao Guangping; Deng Zongquan; Shan Baohua; Yu Weizhen; Li Lifang

    2010-01-01

    A manual inspection of large-diameter tubular joints is difficult. As a result a scanner with three degrees of freedom (DOFs) was developed based on the scanning principle of ultrasonic phased array. The weld tracing is realized by a 2D0F motion of scanner. The pose of ultrasonic probe is controlled by the third one. The control strategy is put forward based on a programmable multi-axis controller. Four kinds of scanning modes can be implemented simultaneously employing this ultrasonic inspection system. Experiments on reference blocks of tubular joints reveal that the automatic ultrasonic phased array inspection system has the same inspection accuracy as a manual ultrasonic inspection. This system is superior to the manual ultrasonic system in terms of reliability and repeatability. The artificial defects of weld at tubular joint can be detected accurately with the presented inspection system.

  12. Capillary electrophoresis study on segment/segment system for segments based on phase of mixed micelles and its role in transport of particles between the two segments

    Czech Academy of Sciences Publication Activity Database

    Oszwaldowski, S.; Kubáň, Pavel

    2015-01-01

    Roč. 1412, SEP (2015), s. 139-150. ISSN 0021-9673 R&D Projects: GA ČR(CZ) GA13-05762S Institutional support: RVO:68081715 Keywords : capillary electrophoresis * mixed micelles * nanocrystals Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 4.169, year: 2014

  13. Digital Spectro-Correlator System for the Atacama Compact Array of the Atacama Large Millimeter/submillimeter Array

    OpenAIRE

    Kamazaki, T.; Okumura, S. K.; Chikada, Y.; Okuda, T; Kurono, Y.; Iguchi, S.; Mitsuishi, S.; Murakami, Y.; Nishimuta, N.; Mita, H.; Sano, R.

    2011-01-01

    We have developed an FX-architecture digital spectro-correlator for the Atacama Compact Array (ACA) of the Atacama Large Millimeter/submillimeter Array. The correlator is able to simultaneously process four pairs of dual polarization signals with the bandwidth of 2 GHz, which are received by up to sixteen antennas. It can calculate auto- and cross-correlation spectra including cross-polarization in all combinations of all the antennas, and output correlation spectra with flexible spectral con...

  14. Gravitational waves from resolvable massive black hole binary systems and observations with Pulsar Timing Arrays

    CERN Document Server

    Sesana, A; Volonteri, M

    2008-01-01

    Massive black holes are key components of the assembly and evolution of cosmic structures and a number of surveys are currently on-going or planned to probe the demographics of these objects and to gain insight into the relevant physical processes. Pulsar Timing Arrays (PTAs) currently provide the only means to observe gravitational radiation from massive black hole binary systems with masses >10^7 solar masses. The whole cosmic population produces a stochastic background that could be detectable with upcoming Pulsar Timing Arrays. Sources sufficiently close and/or massive generate gravitational radiation that significantly exceeds the level of the background and could be individually resolved. We consider a wide range of massive black hole binary assembly scenarios, we investigate the distribution of the main physical parameters of the sources, such as masses and redshift, and explore the consequences for Pulsar Timing Arrays observations. Depending on the specific massive black hole population model, we est...

  15. The Failure Analysis of Paralleled Solar Array Regulator for Satellite Power System in Low Earth Orbit

    Science.gov (United States)

    Jang, Sung-Soo; Kim, Sung-Hoon; Lee, Sang-Ryool; Choi, Jaeho

    2011-06-01

    A satellite power system should generate and supply sufficient electric power to perform the satellite mission successfully during the satellite mission period, and it should be developed to be strong to the failure caused by the severe space environment. A satellite power system must have a high reliability with respect to failure. Since it cannot be repaired after launching, different from a ground system, the failures that may happen in space as well as the effect of the failures on the system should be considered in advance. However, it is difficult to use all the hardware to test the performance of the satellite power system to be developed in order to consider the failure mechanism of the electrical power system. Therefore, it is necessary to develop an accurate model for the main components of a power system and, based on that, to develop an accurate model for the entire power system. Through the power system modeling, the overall effect of failure on the main components of the power system can be considered and the protective design can be devised against the failure. In this study, to analyze the failure mode of the power system and the effects of the failure on the power system, we carried out modeling of the main power system components including the solar array regulator, and constituted the entire power system based on the modeling. Additionally, we investigated the effects of representative failures in the solar array regulator on the power system using the power system model.

  16. Design of a Solar Motor Drive System Fed by a Direct-Connected Photovoltaic Array

    OpenAIRE

    AYDOGMUS, O.

    2012-01-01

    A solar motor pump drive system is modeled and simulated. The proposed drive system does not require any kind of energy storage system and dc-dc converter. The system is connected directly to a photovoltaic (PV) array. Thus, a low cost solar system can be achieved. A vector controlled Permanent Magnet Synchronous Motor (PMSM) is used as a solar motor to increase the efficiency of system. The motor is designed for a low rated voltage level about 24V. The hill climbing MPPT method is used f...

  17. Denaturing gradient gel electrophoresis

    International Nuclear Information System (INIS)

    It is worthwhile considering that only some 30 species make up the bulk of the bacterial population in human faeces at any one time based on the classical cultivation-based approach. The situation in the rumen is similar. Thus, it is practical to focus on specific groups of interest within the complex community. These may be the predominant or the most active species, specific physiological groups or readily identifiable (genetic) clusters of phylogenetically related organisms. Several 16S rDNA fingerprinting techniques can be invaluable for selecting and monitoring sequences or phylogenetic groups of interest and are described below. Over the past few decades, considerable attention was focussed on the identification of pure cultures of microbes on the basis of genetic polymorphisms of DNA encoding rRNA such as ribotyping, amplified fragment length polymorphism and randomly amplified polymorphic DNA. However, many of these methods require prior cultivation and are less suitable for use in analysis of complex mixed populations although important in describing cultivated microbial diversity in molecular terms. Much less attention was given to molecular characterization of complex communities. In particular, research into diversity and community structure over time has been revolutionized by the advent of molecular fingerprinting techniques for complex communities. Denaturing or temperature gradient gel electrophoresis (DGGE/TGGE) methods have been successfully applied to the analysis of human, pig, cattle, dog and rodent intestinal populations

  18. A microfluidic distribution system for an array of hollow microneedles

    International Nuclear Information System (INIS)

    We report a microfluidic device able to control the ejection of fluid through a matrix of out-of-plane microneedles. The device comprises a matrix of open dispensing units connected to needles and filled by a common filling system. A deformable membrane (e.g. in PDMS) is brought into contact with the dispensing units. Pressure exerted on the deformable membrane closes (and thus individualizes) each dispensing unit and provokes the ejection of the dispensing unit content through the outlets. Sufficient pressure over the deformable membrane ensures that all dispensing units deliver a fixed volume (their content) irrespective of the hydrodynamic pressure outside the dispensing unit outlet. The size of the ensemble matrix of dispensing units, the number of liquid reservoirs, as well as the material can vary depending on the considered application of the device or on the conditions of use. In the present paper, the liquid reservoirs are geometrically identical. The geometrical parameters of the device are optimized to avoid as much dead volume as possible, as it was to handle plasmid DNA solutions which are very expensive. The conception, the fabrication and the experimental results are described in this paper. Our prototype is conceived to inject in a uniform way 10 µl of drug through 100 microneedles distributed over 1 cm2

  19. Self-Adaptive System based on Field Programmable Gate Array for Extreme Temperature Electronics

    Science.gov (United States)

    Keymeulen, Didier; Zebulum, Ricardo; Rajeshuni, Ramesham; Stoica, Adrian; Katkoori, Srinivas; Graves, Sharon; Novak, Frank; Antill, Charles

    2006-01-01

    In this work, we report the implementation of a self-adaptive system using a field programmable gate array (FPGA) and data converters. The self-adaptive system can autonomously recover the lost functionality of a reconfigurable analog array (RAA) integrated circuit (IC) [3]. Both the RAA IC and the self-adaptive system are operating in extreme temperatures (from 120 C down to -180 C). The RAA IC consists of reconfigurable analog blocks interconnected by several switches and programmable by bias voltages. It implements filters/amplifiers with bandwidth up to 20 MHz. The self-adaptive system controls the RAA IC and is realized on Commercial-Off-The-Shelf (COTS) parts. It implements a basic compensation algorithm that corrects a RAA IC in less than a few milliseconds. Experimental results for the cold temperature environment (down to -180 C) demonstrate the feasibility of this approach.

  20. An electrical impedance tomography system for gynecological application GIT with a tiny electrode array

    International Nuclear Information System (INIS)

    The paper describes the development of an electrical impedance tomography (EIT) system for gynecologic research. The GIT (gynecological impedance tomography) system has 48 electrodes and is embedded on a small space (30 mm diameter and 20 mm height) inside of the vaginal probe. The system provides real-time (one shot per second) 3D visualization of the spatial distribution of the static electrical properties of the cervix tissue. History, advantages, disadvantages and aspects of the system development are also described. The algorithm for the tiny measuring array organization is given. New details of the backprojection method on the non-regular electrode array are discussed. Some pictures reconstructed from numerical simulated data are offered. 3D visualization of the test object and cervix is presented. (paper)

  1. The calibration system for the photomultiplier array of the SNO+ experiment

    CERN Document Server

    Alves, R; Bradbury, S; Carvalho, J; Chauhan, D; Clark, K; Coulter, I; Descamps, F; Falk, E; Gurriana, L; Kraus, C; Lefeuvre, G; Maio, A; Maneira, J; Mottram, M; Peeters, S; Rose, J; Seabra, L; Sinclair, J; Skensved, P; Waterfield, J; White, R; Wilson, J R

    2014-01-01

    A light injection system using LEDs and optical fibres was designed for the calibration and monitoring of the photomultiplier array of the SNO+ experiment at SNOLAB. Large volume, non-segmented, low-background detectors for rare event physics, such as the multi-purpose SNO+ experiment, need a calibration system that allow an accurate and regular measurement of the performance parameters of their photomultiplier arrays, while minimising the risk of radioactivity ingress. The design implemented for SNO+ uses a set of optical fibres to inject light pulses from external LEDs into the detector. The design, fabrication and installation of this light injection system, as well as the first commissioning tests, are described in this paper. Monte Carlo simulations were compared with the commissioning test results, confirming that the system meets the performance requirements.

  2. The calibration system for the photomultiplier array of the SNO+ experiment

    Science.gov (United States)

    Alves, R.; Andringa, S.; Bradbury, S.; Carvalho, J.; Chauhan, D.; Clark, K.; Coulter, I.; Descamps, F.; Falk, E.; Gurriana, L.; Kraus, C.; Lefeuvre, G.; Maio, A.; Maneira, J.; Mottram, M.; Peeters, S.; Rose, J.; Seabra, L.; Sinclair, J.; Skensved, P.; Waterfield, J.; White, R.; Wilson, J. R.

    2015-03-01

    A light injection system using LEDs and optical fibres was designed for the calibration and monitoring of the photomultiplier array of the SNO+ experiment at SNOLAB. Large volume, non-segmented, low-background detectors for rare event physics, such as the multi-purpose SNO+ experiment, need a calibration system that allow an accurate and regular measurement of the performance parameters of their photomultiplier arrays, while minimising the risk of radioactivity ingress. The design implemented for SNO+ uses a set of optical fibres to inject light pulses from external LEDs into the detector. The design, fabrication and installation of this light injection system, as well as the first commissioning tests, are described in this paper. Monte Carlo simulations were compared with the commissioning test results, confirming that the system meets the performance requirements.

  3. Frequency Tunable Antennas and Novel Phased Array Feeding Networks for Next Generation Communication Systems

    Science.gov (United States)

    Avser, Bilgehan

    The thesis presents three dual-band frequency tunable antennas for carrier aggregation systems and two new feeding networks for reducing the number of phase shifters in limited-scan arrays. First, single- and dual-feed, dual-frequency, low-profile antennas with independent frequency tuning using varactor diodes are presented. The dual-feed planar inverted F-antenna (PIFA) has two operating frequencies which are independently tuned at 0.7--1.1 GHz and at 1.7--2.3 GHz with better than 10 dB impedance match. The isolation between the high-band and the low-band ports is > 13 dB; hence, one resonant frequency can be tuned without affecting the other. The single-feed contiguous-dual-band antenna has two resonant frequencies, which are independently tuned at 1.2--1.6 GHz at 1.6--2.3 GHz with better than 10 dB impedance match for most of the tuning range. And the single-feed dual-band antenna has two resonant frequencies, which are independently tuned at 0.7--1.0 GHz at 1.7--2.3 GHz with better than 10 dB impedance match for most of the tuning range. The tuning is done using varactor diodes with a capacitance range from 0.8 to 3.8 pF, which is compatible with RF MEMS devices. The antenna volumes are 63 x 100 x 3.15 mm3 on epsilon r = 3.55 substrates and the measured antenna efficiencies vary between 25% and 50% over the tuning range. The application areas are in carrier aggregation systems for fourth generation (4G) wireless systems. Next, a new phased array feeding network that employs random sequences of non-uniform sub-arrays (and a single phase shifter for each sub-array) is presented. When these sequences are optimized, the resulting phased arrays can scan over a wide region with low sidelobe levels. Equations for analyzing the random arrays and an algorithm for optimizing the array sequences are presented. Multiple random-solutions with different number of phase shifters and different set of sub-array groups are analyzed and design guidelines are presented. The

  4. Impacts on the Electrical System Economics from Critical Design Factors of Wave Energy Converters and Arrays

    OpenAIRE

    Sharkey, Fergus; Conlon, Michael; Gaughan, Kevin

    2013-01-01

    It is expected that ultimately, like offshore wind farms, electrical systems will make up to a quarter of the overall Capex of wave farms. This is a significant element of cost and consideration must be taken in the design of both individual wave energy converters (WECs) and arrays of WECs to ensure that these costs can be minimised. In a worst case scenario design decisions could increase the cost of the electrical system by several orders and ultimately make the technology uncompetitive. ...

  5. Proceedings of the flat-plate solar array project research forum on photovoltaic metallization systems

    Energy Technology Data Exchange (ETDEWEB)

    None

    1983-11-15

    A Photovoltaic Metallization Research Forum, under the sponsorship of the Jet Propulsion Laboratory's Flat-Plate Solar Array Project and the US Department of Energy, was held March 16-18, 1983 at Pine Mountain, Georgia. The Forum consisted of five sessions, covering (1) the current status of metallization systems, (2) system design, (3) thick-film metallization, (4) advanced techniques and (5) future metallization challenges. Twenty-three papers were presented.

  6. A control system based on field programmable gate array for papermaking sewage treatment

    Science.gov (United States)

    Zhang, Zi Sheng; Xie, Chang; Qing Xiong, Yan; Liu, Zhi Qiang; Li, Qing

    2013-03-01

    A sewage treatment control system is designed to improve the efficiency of papermaking wastewater treatment system. The automation control system is based on Field Programmable Gate Array (FPGA), coded with Very-High-Speed Integrate Circuit Hardware Description Language (VHDL), compiled and simulated with Quartus. In order to ensure the stability of the data used in FPGA, the data is collected through temperature sensors, water level sensor and online PH measurement system. The automatic control system is more sensitive, and both the treatment efficiency and processing power are increased. This work provides a new method for sewage treatment control.

  7. A control system based on field programmable gate array for papermaking sewage treatment

    International Nuclear Information System (INIS)

    A sewage treatment control system is designed to improve the efficiency of papermaking wastewater treatment system. The automation control system is based on Field Programmable Gate Array (FPGA), coded with Very-High-Speed Integrate Circuit Hardware Description Language (VHDL), compiled and simulated with Quartus. In order to ensure the stability of the data used in FPGA, the data is collected through temperature sensors, water level sensor and online PH measurement system. The automatic control system is more sensitive, and both the treatment efficiency and processing power are increased. This work provides a new method for sewage treatment control.

  8. Integration of amperometric sensors for microchip capillary electrophoresis application

    International Nuclear Information System (INIS)

    Capillary electrophoresis is a technique for the separation and analysis of chemical compounds. Techniques adopted from the microchip technology knowledge have led to recent developments of electrophoresis system with integration on microchip. Microchip Capillary Electrophoresis (μCE) systems offer a series of advantages as easy integration for Lab-on-a-chip applications, high performance, portability, speed, minimal solvent and sample requirements. A new technological challenge aims at the development of an economic modular microchip capillary electrophoresis systems using separable and independent units concerning the sensor. In this project we worked on the development of an interchangeable amperometric sensor in order to provide a solution to such electrode passivation and facilitating the use of tailored sensors for specific analyte detection besides. Fluidic chips have been machined from cyclic olefin polymer pallets (Zeonor) using a micro-injection molding machine.

  9. Detection of Volatile Organics Using a Surface Acoustic Wave Array System

    Energy Technology Data Exchange (ETDEWEB)

    ANDERSON, LAWRENCE F.; BARTHOLOMEW, JOHN W.; CERNOSEK, RICHARD W.; COLBURN, CHRISTOPHER W.; CROOKS, R.M.; MARTINEZ, R.F.; OSBOURN, GORDON C.; RICCO, A.J.; STATON, ALAN W.; YELTON, WILLIAM G.

    1999-10-14

    A chemical sensing system based on arrays of surface acoustic wave (SAW) delay lines has been developed for identification and quantification of volatile organic compounds (VOCs). The individual SAW chemical sensors consist of interdigital transducers patterned on the surface of an ST-cut quartz substrate to launch and detect the acoustic waves and a thin film coating in the SAW propagation path to perturb the acoustic wave velocity and attenuation during analyte sorption. A diverse set of material coatings gives the sensor arrays a degree of chemical sensitivity and selectivity. Materials examined for sensor application include the alkanethiol-based self-assembled monolayer, plasma-processed films, custom-synthesized conventional polymers, dendrimeric polymers, molecular recognition materials, electroplated metal thin films, and porous metal oxides. All of these materials target a specific chemical fi.mctionality and the enhancement of accessible film surface area. Since no one coating provides absolute analyte specificity, the array responses are further analyzed using a visual-empirical region-of-influence (VERI) pattern recognition algorithm. The chemical sensing system consists of a seven-element SAW array with accompanying drive and control electronics, sensor signal acquisition electronics, environmental vapor sampling hardware, and a notebook computer. Based on data gathered for individual sensor responses, greater than 93%-accurate identification can be achieved for any single analyte from a group of 17 VOCs and water.

  10. Linear CCD attitude measurement system based on the identification of the auxiliary array CCD

    Science.gov (United States)

    Hu, Yinghui; Yuan, Feng; Li, Kai; Wang, Yan

    2015-10-01

    Object to the high precision flying target attitude measurement issues of a large space and large field of view, comparing existing measurement methods, the idea is proposed of using two array CCD to assist in identifying the three linear CCD with multi-cooperative target attitude measurement system, and to address the existing nonlinear system errors and calibration parameters and more problems with nine linear CCD spectroscopic test system of too complicated constraints among camera position caused by excessive. The mathematical model of binocular vision and three linear CCD test system are established, co-spot composition triangle utilize three red LED position light, three points' coordinates are given in advance by Cooperate Measuring Machine, the red LED in the composition of the three sides of a triangle adds three blue LED light points as an auxiliary, so that array CCD is easier to identify three red LED light points, and linear CCD camera is installed of a red filter to filter out the blue LED light points while reducing stray light. Using array CCD to measure the spot, identifying and calculating the spatial coordinates solutions of red LED light points, while utilizing linear CCD to measure three red LED spot for solving linear CCD test system, which can be drawn from 27 solution. Measured with array CCD coordinates auxiliary linear CCD has achieved spot identification, and has solved the difficult problems of multi-objective linear CCD identification. Unique combination of linear CCD imaging features, linear CCD special cylindrical lens system is developed using telecentric optical design, the energy center of the spot position in the depth range of convergence in the direction is perpendicular to the optical axis of the small changes ensuring highprecision image quality, and the entire test system improves spatial object attitude measurement speed and precision.

  11. Fibre coupled micro-light emitting diode array light source with integrated band-pass filter for fluorescence detection in miniaturised analytical systems

    OpenAIRE

    Vaculovicova, Marketa; Akther, Mahbub; Maaskant, Pleun; Brabazon, Dermot

    2015-01-01

    In this work, a new type of miniaturized fibre-coupled solid-state light source is demonstrated as an excitation source for fluorescence detection in capillary electrophoresis. It is based on a parabolically shaped micro- light emitting diode (µ-LED) array with a custom band-pass optical interference filter (IF) deposited at the back of the LED substrate. The GaN µ-LED array consisted of 270 individual µ-LED elements with peak emission at 470nm, each about 14µm in diameter and operated as a s...

  12. The LED and fiber based calibration system for the photomultiplier array of SNO+

    International Nuclear Information System (INIS)

    A new external LED/fiber light injection calibration system was designed for the calibration and monitoring of the photomultiplier array of the SNO+ experiment at SNOLAB. The goal of the calibration system is to allow an accurate and regular measurement of the photomultiplier array's performance, while minimizing the risk of radioactivity ingress. The choice in SNO+ was to use a set of optical fiber cables to convey into the detector the light pulses produced by external LEDs. The quality control was carried out using a modified test bench that was used in QC of optical fibers for TileCal/ATLAS. The optical fibers were characterized for transmission, timing and angular dispersions. This article describes the setups used for the characterization and quality control of the system based on LEDs and optical fibers and their results

  13. Proof of Concept of an Irradiance Estimation System for Reconfigurable Photovoltaic Arrays

    Directory of Open Access Journals (Sweden)

    Vincenzo Li Vigni

    2015-06-01

    Full Text Available In order to reduce the mismatch effect caused by non-uniform shadows in PV arrays, reconfigurable interconnections approaches have been recently proposed in the literature. These systems usually require the knowledge of the solar radiation affecting every solar module. The aim of this work is to evaluate the effectiveness of three irradiance estimation approaches in order to define which can be well suited for reconfigurable PV arrays. It is presented a real-time solar irradiance estimation device (IrradEst, implementing the three different estimation methods. The proposed system is based on mathematical models of PV modules enabling to estimate irradiation values by sensing a combination of temperature, voltage and current of a PV module. Experimental results showed generally good agreement between the estimated irradiances and the measurements performed by a standard pyranometer taken as reference. Finally one of the three methods was selected as possible solution for a reconfigurable PV system.

  14. Stability Measurements for Alignment of the NIF Neutron Imaging System Pinhole Array

    International Nuclear Information System (INIS)

    The alignment system for the National Ignition Facility's neutron imaging system has been commissioned and measurements of the relative stability of the 90-315 DIM, the front and the back of the neutron imaging pinhole array and an exploding pusher target have been made using the 90-135 and the 90-258 opposite port alignment systems. Additionally, a laser beam shot from the neutron-imaging Annex and reflected from a mirror at the back of the pinhole array was used to monitor the pointing of the pinhole. Over a twelve hour period, the relative stability of these parts was found to be within ∼ ±18 (micro)m rms even when using manual methods for tracking the position of the objects. For highly visible features, use of basic particle tracking techniques found that the front of the pinhole array was stable relative to the 90-135 opposite port alignment camera to within ±3.4 (micro)m rms. Reregistration, however, of the opposite port alignment systems themselves using the target alignment sensor was found to change the expected position of target chamber center by up to 194 (micro)m.

  15. Considerations for Using Phased Array Ultrasonics in a Fully Automated Inspection System

    Science.gov (United States)

    Kramb, V. A.; Olding, R. B.; Sebastian, J. R.; Hoppe, W. C.; Petricola, D. L.; Hoeffel, J. D.; Gasper, D. A.; Stubbs, D. A.

    2004-02-01

    The University of Dayton Research Institute (UDRI) under contract by the US Air Force has designed and constructed a fully automated ultrasonic inspection system for the detection of embedded defects in rotating gas turbine engine components. The system performs automated inspections using the "scan plan" concept developed for the Air Force sponsored "Retirement For Cause" (RFC) automated eddy current system. Execution of the scan plan results in a fully automated inspection process producing engine component accept/reject decisions based on probability of detection (POD) information. Use of the phased-array ultrasonic instrument and probes allows for optimization of both the sensitivity and resolution for each inspection through electronic beamforming, scanning, and focusing processes. However, issues such as alignment of the array probe, calibration of individual elements and overall beam response prior to the inspection have not been addressed for an automated system. This paper will discuss current progress in the development of an automated alignment and calibration procedure for various phased array apertures and specimen geometries.

  16. Field inversion gel electrophoresis with different pulse time ramps.

    OpenAIRE

    Heller, C.(Fakultät für Physik, Ludwig-Maximilians-Universität München, München, Germany); Pohl, F M

    1990-01-01

    The influence of different pulse time ramps on the separation of yeast chromosomes with field inversion gel electrophoresis (FIGE) was investigated by the means of two dimensional gel electrophoresis. The problem of band inversion, which makes it difficult to distinguish DNA molecules of different size, has been solved by using double randomized pulse times. A major disadvantage of the field inversion technique is thereby overcome, making this system comparable to other pulsed field techniques.

  17. Field-portable Capillary Electrophoresis Instrument with Conductivity Detection

    International Nuclear Information System (INIS)

    In this paper a novel capillary electrophoresis chip (CEC) is presented with integrated platinum electrodes and simplified conductivity detector. CEC is fabricated by the method of mechanical modification with probe on organic glass. Capillary electrophoresis chip can rapidly completed ion separation by simulation of concentration distribution and zone-broadening. Detection circuit is simple which can detect pA order current. This system has those advantages such as small volume, low power consumption and linearity, and well suit for field analysis

  18. Sample volume misregistration in linear array-based dual beam Doppler ultrasound systems.

    Science.gov (United States)

    Steel, Robin; Fish, Peter J

    2003-07-01

    Large velocity estimation errors can occur in dual beam Doppler ultrasound velocity measurement systems when there is left/right sample volume misregistration, particularly when the interbeam angle is small. Such misregistration will occur when there is tissue inhomogeneity. This is investigated for a typical type of inhomogeneity--a layer of fat--by calculating the amount of both angle and translation misregistration occurring in such a system realized using a single linear array transducer. The complex sample volume sensitivity is calculated using a modified time domain approach, combining the spatial impulse response method with ray tracing. The effects on these misregistrations of altering the aperture sizes and their relative positions on the array is then investigated to derive an improved aperture configuration for dual beam velocity estimation. Arrangements with transmit apertures wider than the receive apertures are shown to be preferable in this context. PMID:12894917

  19. FPGA-Based Communications Receivers for Smart Antenna Array Embedded Systems

    Directory of Open Access Journals (Sweden)

    James Millar

    2006-10-01

    Full Text Available Field-programmable gate arrays (FPGAs are drawing ever increasing interest from designers of embedded wireless communications systems. They outpace digital signal processors (DSPs, through hardware execution of a wide range of parallelizable communications transceiver algorithms, at a fraction of the design and implementation effort and cost required for application-specific integrated circuits (ASICs. In our study, we employ an Altera Stratix FPGA development board, along with the DSP Builder software tool which acts as a high-level interface to the powerful Quartus II environment. We compare single- and multibranch FPGA-based receiver designs in terms of error rate performance and power consumption. We exploit FPGA operational flexibility and algorithm parallelism to design eigenmode-monitoring receivers that can adapt to variations in wireless channel statistics, for high-performing, inexpensive, smart antenna array embedded systems.

  20. Numerical Results for the System Noise Temperature of an Aperture Array Tile and Comparison with Measurements

    CERN Document Server

    Ivashina, M V; Bakker, L; Witvers, R H

    2011-01-01

    The purpose of this report is to document the noise performance of a complex beamforming array antenna system and to characterize the recently developed noise measurement facility called THACO, which was developed at ASTRON. The receiver system includes the array antenna of strongly coupled 144 TSA elements, 144 Low Noise Amplifiers (LNAs) (Tmin =35-40K) and the data recording/storing facilities of the initial test station that allow for off-line digital beamforming. The primary goal of this study is to compare the measured receiver noise temperatures with the simulated values for several practical beamformers, and to predict the associated receiver noise coupling contribution, antenna thermal noise and ground noise pick-up (due to the back radiation).

  1. FPGA-Based Communications Receivers for Smart Antenna Array Embedded Systems

    Directory of Open Access Journals (Sweden)

    Millar James

    2006-01-01

    Full Text Available Field-programmable gate arrays (FPGAs are drawing ever increasing interest from designers of embedded wireless communications systems. They outpace digital signal processors (DSPs, through hardware execution of a wide range of parallelizable communications transceiver algorithms, at a fraction of the design and implementation effort and cost required for application-specific integrated circuits (ASICs. In our study, we employ an Altera Stratix FPGA development board, along with the DSP Builder software tool which acts as a high-level interface to the powerful Quartus II environment. We compare single- and multibranch FPGA-based receiver designs in terms of error rate performance and power consumption. We exploit FPGA operational flexibility and algorithm parallelism to design eigenmode-monitoring receivers that can adapt to variations in wireless channel statistics, for high-performing, inexpensive, smart antenna array embedded systems.

  2. Detection of Crab Giant Pulses Using the Mileura Widefield Array Low Frequency Demonstrator Field Prototype System

    OpenAIRE

    Bhat, N. D. Ramesh; Wayth, Randall B.; Knight, Haydon S.; Bowman, Judd D.; Oberoi, Divya; Barnes, David G.; Briggs, Frank H.; Cappallo, Roger J.; Herne, David; Kocz, Jonathon; Lonsdale, Colin J.; Lynch, Mervyn J.; Stansby, Bruce; Stevens, Jamie; Torr, Glen

    2007-01-01

    We report on the detection of giant pulses from the Crab Nebula pulsar at a frequency of 200 MHz using the field deployment system designed for the Mileura Widefield Array's Low Frequency Demonstrator (MWA-LFD). Our observations are among the first high-quality detections at such low frequencies. The measured pulse shapes are deconvolved for interstellar pulse broadening, yielding a pulse-broadening time of 670$\\pm$100 $\\mu$s, and the implied strength of scattering (scattering measure) is the...

  3. Electrical PV array reconfiguration strategy for energy extraction improvement in grid-connected PV systems

    OpenAIRE

    Velasco Quesada, Guillermo; Guinjoan Gispert, Francisco; Piqué López, Robert; Román Lumbreras, Manuel; Alfonso, Conesa

    2009-01-01

    This paper applies a dynamical electrical array reconfiguration (EAR) strategy on the photovoltaic (PV) generator of a grid-connected PV system based on a plant-oriented configuration, in order to improve its energy production when the operating conditions of the solar panels are different. The EAR strategy is carried out by inserting a controllable switching matrix between the PV generator and the central inverter, which allows the electrical reconnection of the available PV modules. A...

  4. Concept of Bee-Eyes Array of Fresnel Lenses as a Solar Photovoltaic Concentrator System

    OpenAIRE

    Nura Liman Chiromawa; Kamarulazizi Ibrahim

    2015-01-01

    This paper presents a proposal of a new configuration of an optical concentrator for photovoltaic application which may enhance the efficiency of solar cells. Bee-eyes array Fresnel lenses concentrator proposed here provide high concentration factor which is greater than1000x at the 20th zone. In addition, the system also provides room for increasing the number of zones to achieve the high concentration factor if needs arise. The transmission efficiency greater than 90% has been achieved with...

  5. Performance Enhancement of Underwater Target Tracking by Fusing Data of Array of Global Positioning System Sonobuoys

    OpenAIRE

    Ahmed El-Shafie; Abdallah Osman; Aboelmagd Noureldin; Aini Hussien

    2009-01-01

    Problem statement: An accurate knowledge of geographic positions of sonobuoys is critical for the conduct of antisubmarine warfare operations and detected target localization. Deployed from an airborne platform or a surface vessel, arrays of sonobuoys could be used to efficiently track and localize submarines. Lastly, some sonobuoys were being equipped with GPS for improving system accuracy and potentially allowing networked Sonobuoy positioning. However, the computation of the range using th...

  6. FPGA-Based Communications Receivers for Smart Antenna Array Embedded Systems

    OpenAIRE

    James Millar; Steven D. Blostein; Constantin Siriteanu

    2006-01-01

    Field-programmable gate arrays (FPGAs) are drawing ever increasing interest from designers of embedded wireless communications systems. They outpace digital signal processors (DSPs), through hardware execution of a wide range of parallelizable communications transceiver algorithms, at a fraction of the design and implementation effort and cost required for application-specific integrated circuits (ASICs). In our study, we employ an Altera Stratix FPGA development board, along with the DSP Bu...

  7. Performance of Indian National Gamma Array (INGA) Coupled with a Fast Digital Data Acquisition System for Nuclear Structure Studies

    International Nuclear Information System (INIS)

    The Indian National Gamma Array (INGA) is set up at TIFR-BARC accelerator facility, as a part of a national collaboration between different research Institutes and Universities. The array is designed for 24 Compton suppressed clover detectors providing around 5% photo-peak efficiency. Recently, a digital data acquisition system with 96 channels (based on Pixie-16 modules developed by XIA LLC) has been implemented for this Compton suppressed clover array. The digital system provides higher throughput, better energy resolution and better stability for the multi-detector Compton suppressed clover array compared to its previous conventional system with analog shaping. A number of nuclear spectroscopic experiments have been carried out using the array. The results from the initial in-beam experiments of the complete set-up will be discussed in this paper.

  8. Testing System Based on Virtual Instrument for Readout Circuit of Infrared Focal Plane Array

    Institute of Scientific and Technical Information of China (English)

    XUE Lian; MENG Li-ya; YUAN Xiang-hui

    2008-01-01

    Readout integrated circuit(ROIC) is one of the most important components for hybrid-integrated infrared focal plane array(IRFPA). And it should be tested to ensure the product yield before bonding. This paper presents an on-wafer testing system based on Labview for ROIC of IRFPA. The quantitative measurement can be conducted after determining whether there is row crosstalk or not in this system. This low-cost system has the benefits of easy expansion, upgrading, and flexibility, and it has been employed in the testing of several kinds of IRFPA ROICs to measure the parameters of saturated output voltage, non-uniformity, dark noise and dynamic range, etc.

  9. A digital combining-weight estimation algorithm for broadband sources with the array feed compensation system

    Science.gov (United States)

    Vilnrotter, V. A.; Rodemich, E. R.

    1994-01-01

    An algorithm for estimating the optimum combining weights for the Ka-band (33.7-GHz) array feed compensation system was developed and analyzed. The input signal is assumed to be broadband radiation of thermal origin, generated by a distant radio source. Currently, seven video converters operating in conjunction with the real-time correlator are used to obtain these weight estimates. The algorithm described here requires only simple operations that can be implemented on a PC-based combining system, greatly reducing the amount of hardware. Therefore, system reliability and portability will be improved.

  10. [Study on UV-visible DOAS system based on photodiode array (PDA)].

    Science.gov (United States)

    Qin, Min; Xie, Pin-hua; Liu, Jian-guo; Liu, Wen-qing; Fang, Wu; Lu, Fan; Li, Ang; Lu, Yi-huai; Wei, Qing-nong; Dou, Ke

    2005-09-01

    A long-path differential optical absorption spectroscopy (DOAS) system is introduced. A photodiode array is employed as the detector to replace the complicated SD detector which consists of a PMT and a slotted disk. The properties of the detector and the spectrometer unit such as offset, dark current, noise, linearity, resolution, and wavelength range were measured. This system was also tested to measure SO2 and NO2 in the atmosphere. The detection limits of this system for SO2, and NO2 over a 713 m light path were determined. PMID:16379291

  11. Fault tolerant attitude control for small unmanned aircraft systems equipped with an airflow sensor array

    International Nuclear Information System (INIS)

    Inspired by sensing strategies observed in birds and bats, a new attitude control concept of directly using real-time pressure and shear stresses has recently been studied. It was shown that with an array of onboard airflow sensors, small unmanned aircraft systems can promptly respond to airflow changes and improve flight performances. In this paper, a mapping function is proposed to compute aerodynamic moments from the real-time pressure and shear data in a practical and computationally tractable formulation. Since many microscale airflow sensors are embedded on the small unmanned aircraft system surface, it is highly possible that certain sensors may fail. Here, an adaptive control system is developed that is robust to sensor failure as well as other numerical mismatches in calculating real-time aerodynamic moments. The advantages of the proposed method are shown in the following simulation cases: (i) feedback pressure and wall shear data from a distributed array of 45 airflow sensors; (ii) 50% failure of the symmetrically distributed airflow sensor array; and (iii) failure of all the airflow sensors on one wing. It is shown that even if 50% of the airflow sensors have failures, the aircraft is still stable and able to track the attitude commands. (paper)

  12. Flatbed-type omnidirectional three-dimensional display system using holographic lens array

    Science.gov (United States)

    Takahashi, Hideya; Chikayama, Manabu; Yamada, Kenji

    2008-02-01

    We propose an omnidirectional three-dimensional (3D) display system for multiple users as an improved version of our previous thin natural 3D display based on the ray reconstruction method. This is a tool for communication around a 3D image among a small number of people. It is a flatbed-type autostereoscopic 3D display system. It consists of some flat panel displays and some holographic lens array sheets. Its notable feature is the ability to display natural 3D images which are visible to multiple viewers at the same time. Moreover, 3D real images float over the proposed flatbed-type display. Thus, proposed display allows two or more people surrounding it to simultaneously observe floating 3D images from their own viewpoints. The prototype display consists of two DMD (digital micromirror device) projectors and two holographic lens array sheets. The number of the 3D pixels about one holographic lens array sheet is 48×96. Reconstructed 3D images are superimposed over the display. Therefore, this can display a floating 3D image which size is 108 mm ×80.8 mm ×80.8 mm. This paper describes a flatbed-type omnidirectional 3D display system, and also describes the experimental results.

  13. Spectral shifts of partially coherent radial array beams passing through ABCD optical systems

    Science.gov (United States)

    Pan, Leilei; Zhang, Bin

    2010-05-01

    The expressions for the spectral intensity of partially coherent Gaussian Schell-model (GSM) radial array beams for both the correlated and uncorrelated superpositions passing through ABCD optical systems have been derived by using the extended Huygens-Fresnel diffraction integral. The effects of the normalized radius R, the number of beamlets N, the spatial coherent parameter of array beamlets β and the optical system parameters on the on-axis and off-axis relative spectral shifts for the two types of superposition have been discussed in detail. The results show that for the correlated superposition, the on-axis spectral intensity in free space and the off-axis spectral intensity on the geometrical focal plane depends on the source spectral density S0( ω), the spatial coherent parameter of array beamlets β, the generalized Fresnel number of the system F, the normalized radius R and the number of beamlets N, whereas the spectral intensity for the uncorrelated superposition is independent of the number of beamlets N. Furthermore, as for on the actual focal plane, the off-axis spectral intensity for the two types of superposition is closely related to N.

  14. Microelectrode array with integrated nanowire FET switches for high-resolution retinal prosthetic systems

    International Nuclear Information System (INIS)

    In this paper, a novel microelectrode array integrated with nanowire field-effect transistor (FET) switches is developed for retinal prosthetic systems. Retinal prosthetic systems require many electrodes (generally more than several hundreds) and this paper presents a novel method of integrating silicon nanowire-FET switches with microelectrodes that can significantly reduce wiring complexity. Also, in order to fit the curvature of an eyeball, the silicon nanowire FETs are transferred to a flexible substrate. In order to demonstrate the concept of using FETs for switching collocated retinal microelectrodes, a microelectrode array with 32 × 32 pixels is fabricated, which has 1,024 microelectrodes. Using the FET switches in a two-dimensional array addressing configuration, 1,024 microelectrodes are addressed by only 64 lines (32 for scan and 32 for data), as compared to requiring 1,024 lines in the conventional one-to-one configuration. With the gate voltage of −5 V, the threshold voltage, current on/off ratio, and on-resistance of the fabricated silicon nanowire-FET switch are −0.4 V, 1 × 107, and 37–47 kΩ, respectively. The maximum allowable current injection limit of the silicon nanowire-FET switch integrated microelectrode is 44 μA with a pulse duration of 1 ms. These results show an excellent potential for high-resolution retinal prosthetic systems. (paper)

  15. Travelling Wave Electrophoresis Due To Selective Currents At Electrodes

    Science.gov (United States)

    Booth, William; Edwards, Boyd

    2015-03-01

    Abstract Using COMSOL finite element modeling software we simulate a 2D traveling-wave electrophoresis (TWE) device for microfluidic chromatography and electrolyte concentration. A periodic array of four electrodes each produce AC potentials shifted by a quarter-period from one another. This yields an electric wave which travels down the channel. Ions of varying mobilities in solution are carried along with the electric wave or left behind at different rates. We employ a simplified model for asymmetric reactions at the electrodes in order to solve the issue of electric double layer shielding at the electrodes. The selective reactions allow for the formation of diffusion layers of ions which attempt to follow the traveling electric wave. We examine the formation of these diffusion layers and how various system parameters affect motion of various ions through the system. With easy control over the traveling electric wave's frequency and direction one may employ this method for concentrating or separating bands of electrolytes. NSF Grant 1066730.

  16. GPS-Like Phasing Control of the Space Solar Power System Transmission Array

    Science.gov (United States)

    Psiaki, Mark L.

    2003-01-01

    The problem of phasing of the Space Solar Power System's transmission array has been addressed by developing a GPS-like radio navigation system. The goal of this system is to provide power transmission phasing control for each node of the array that causes the power signals to add constructively at the ground reception station. The phasing control system operates in a distributed manner, which makes it practical to implement. A leader node and two radio navigation beacons are used to control the power transmission phasing of multiple follower nodes. The necessary one-way communications to the follower nodes are implemented using the RF beacon signals. The phasing control system uses differential carrier phase relative navigation/timing techniques. A special feature of the system is an integer ambiguity resolution procedure that periodically resolves carrier phase cycle count ambiguities via encoding of pseudo-random number codes on the power transmission signals. The system is capable of achieving phasing accuracies on the order of 3 mm down to 0.4 mm depending on whether the radio navigation beacons operate in the L or C bands.

  17. Two-dimensional imaging via a narrowband MIMO radar system with two perpendicular linear arrays.

    Science.gov (United States)

    Wang, Dang-wei; Ma, Xiao-yan; Su, Yi

    2010-05-01

    This paper presents a system model and method for the 2-D imaging application via a narrowband multiple-input multiple-output (MIMO) radar system with two perpendicular linear arrays. Furthermore, the imaging formulation for our method is developed through a Fourier integral processing, and the parameters of antenna array including the cross-range resolution, required size, and sampling interval are also examined. Different from the spatial sequential procedure sampling the scattered echoes during multiple snapshot illuminations in inverse synthetic aperture radar (ISAR) imaging, the proposed method utilizes a spatial parallel procedure to sample the scattered echoes during a single snapshot illumination. Consequently, the complex motion compensation in ISAR imaging can be avoided. Moreover, in our array configuration, multiple narrowband spectrum-shared waveforms coded with orthogonal polyphase sequences are employed. The mainlobes of the compressed echoes from the different filter band could be located in the same range bin, and thus, the range alignment in classical ISAR imaging is not necessary. Numerical simulations based on synthetic data are provided for testing our proposed method. PMID:20040416

  18. Basic research for development of the beam profile monitor based on a Faraday cup array system

    Science.gov (United States)

    Park, Mook-Kwang

    2015-10-01

    The basic design used to develop a beam profile monitor based on a Faraday cup array (FCA), which has the advantages of high robustness, reliability, and long-term stability, along with the ability to measure the ion current over a wide dynamic range, was developed. The total system is divided into three parts: i.e., a faraday cup, measuring electronics, and a display program part. The FCA was considered to consist of a collimator, suppressor, insulator frame, and 64 (8 × 8 array) tiny Faraday cups (FC). An electronic circuit using a multiplexer was applied to effectively address many signal lines and the printed circuit board (PCB) was designed to be divided into three parts, i.e., an electrode PCB (ELEC PCB), capacitance PCB (CAP PCB), and control PCB (CON PCB).

  19. A subtle calculation method for nanoparticle’s molar extinction coefficient: The gift from discrete protein-nanoparticle system on agarose gel electrophoresis

    Science.gov (United States)

    Zhong, Ruibo; Yuan, Ming; Gao, Haiyang; Bai, Zhijun; Guo, Jun; Zhao, Xinmin; Zhang, Feng

    2016-03-01

    Discrete biomolecule-nanoparticle (NP) conjugates play paramount roles in nanofabrication, in which the key is to get the precise molar extinction coefficient of NPs. By making best use of the gift from a specific separation phenomenon of agarose gel electrophoresis (GE), amphiphilic polymer coated NP with exact number of bovine serum albumin (BSA) proteins can be extracted and further experimentally employed to precisely calculate the molar extinction coefficient of the NPs. This method could further benefit the evaluation and extraction of any other dual-component NP-containing bio-conjugates.

  20. Development of a stationary chest tomosynthesis system using carbon nanotube x-ray source array

    Science.gov (United States)

    Shan, Jing

    X-ray imaging system has shown its usefulness for providing quick and easy access of imaging in both clinic settings and emergency situations. It greatly improves the workflow in hospitals. However, the conventional radiography systems, lacks 3D information in the images. The tissue overlapping issue in the 2D projection image result in low sensitivity and specificity. Both computed tomography and digital tomosynthesis, the two conventional 3D imaging modalities, requires a complex gantry to mechanically translate the x-ray source to various positions. Over the past decade, our research group has developed a carbon nanotube (CNT) based x-ray source technology. The CNT x-ray sources allows compacting multiple x-ray sources into a single x-ray tube. Each individual x-ray source in the source array can be electronically switched. This technology allows development of stationary tomographic imaging modalities without any complex mechanical gantries. The goal of this work is to develop a stationary digital chest tomosynthesis (s-DCT) system, and implement it for a clinical trial. The feasibility of s-DCT was investigated. It is found that the CNT source array can provide sufficient x-ray output for chest imaging. Phantom images have shown comparable image qualities as conventional DCT. The s-DBT system was then used to study the effects of source array configurations and tomosynthesis image quality, and the feasibility of a physiological gated s-DCT. Using physical measures for spatial resolution, the 2D source configuration was shown to have improved depth resolution and comparable in-plane resolution. The prospective gated tomosynthesis images have shown substantially reduction of image blur associated with lung motions. The system was also used to investigate the feasibility of using s-DCT as a diagnosis and monitoring tools for cystic fibrosis patients. A new scatter reduction methods for s-DCT was also studied. Finally, a s-DCT system was constructed by

  1. Interference mitigation for simultaneous transmit and receive applications on digital phased array systems

    Science.gov (United States)

    Snow, Trevor M.

    As analog-to-digital (ADC) and digital-to-analog conversion (DAC) technologies become cheaper and digital processing capabilities improve, phased array systems with digital transceivers at every element will become more commonplace. These architectures offer greater capability over traditional analog systems and enable advanced applications such as multiple-input, multiple-output (MIMO) communications, adaptive beamforming, space-time adaptive processing (STAP), and MIMO for radar. Capabilities for such systems are still limited by the need for isolating self-interference from transmitters at co-located receivers. The typical approach of time-sharing the antenna aperture between transmitters and receivers works but leaves the receivers blind for a period of time. For full-duplex operation, some systems use separate frequency bands for transmission and reception, but these require fixed filtering which reduces the system's ability to adapt to its environment and is also an inefficient use of spectral resources. To that end, tunable, high quality-factor filters are used for sub-band isolation and protect receivers while allowing open reception at other frequencies. For more flexibility, another emergent area of related research has focused on co-located spatial isolation using multiple antennas and direct injection of interference cancellation signals into receivers, which enables same-frequency full-duplex operation. With all these methods, self-interference must be reduced by an amount that prevents saturation of the ADC. Intermodulation products generated in the receiver in this process can potentially be problematic, as certain intermodulation products may appear to come from a particular angle and cohere in the beamformer. This work explores various digital phased array architectures and the how the flexibility afforded by an all-digital beamforming architecture, layered with other methods of isolation, can be used to reduce self-interference within the system

  2. Development of a Small Phased Array SAR-MTI System for Tactical UAV

    OpenAIRE

    Rossum, W.L. van; Grooters, R.; Halsema, D. van; Lorga, J.F.M.; Otten, M.P.G.; Vermeulen, B.C.B.; Vlothuizen, W.J.

    2005-01-01

    A small SAR-MTI system is being developed at TNO, aimed at deployment on tactical UAV, such as the SPERWER, in use with the Royal Netherlands Army. The system makes use of modern front-end technology, to provide flexible SAR imaging and MTI modes. Major design goals are 40 kg weight, 500 W power consumption and 50 cm resolution in order to comply with typical tactical UAV constraints and applications. The use of an active phased array antenna has several distinct advantages, not yet found in ...

  3. Theory and investigation of acoustic multiple-input multiple-output systems based on spherical arrays in a room.

    Science.gov (United States)

    Morgenstern, Hai; Rafaely, Boaz; Zotter, Franz

    2015-11-01

    Spatial attributes of room acoustics have been widely studied using microphone and loudspeaker arrays. However, systems that combine both arrays, referred to as multiple-input multiple-output (MIMO) systems, have only been studied to a limited degree in this context. These systems can potentially provide a powerful tool for room acoustics analysis due to the ability to simultaneously control both arrays. This paper offers a theoretical framework for the spatial analysis of enclosed sound fields using a MIMO system comprising spherical loudspeaker and microphone arrays. A system transfer function is formulated in matrix form for free-field conditions, and its properties are studied using tools from linear algebra. The system is shown to have unit-rank, regardless of the array types, and its singular vectors are related to the directions of arrival and radiation at the microphone and loudspeaker arrays, respectively. The formulation is then generalized to apply to rooms, using an image source method. In this case, the rank of the system is related to the number of significant reflections. The paper ends with simulation studies, which support the developed theory, and with an extensive reflection analysis of a room impulse response, using the platform of a MIMO system. PMID:26627773

  4. Establishment of Two-Dimensional Gel Electrophoresis System for Rat Cortex Mitochondria%大鼠皮层线粒体双向凝胶电泳体系的建立

    Institute of Scientific and Technical Information of China (English)

    杨涌涛; 谢鹏; 陈康宁; 黄河清; 贺伟峰

    2013-01-01

    Objective To establish two-dimensional gel electrophoresis system for rat cortex mitochondria. Methods The adult male SD rats were sacrificed by cervical dislocation , the brain tissues quickly harvested and thecortex isolated on ice. The mitochondria were extracted and purified twice by density gradient centrifugation. Two-dimensional gel electrophoresis was performed. Immobilized pH gradient isoelectric focusing (IPG-IEF) was modified and carried out. The gels were focused at 3500 V for a total of 14000Vh and then subjected to SDS-PAGE and silver staining. Results Electrophoregram of rat cerebral cortex mitochondria was obtained with high resolu -tion by using the established two -dimensional gel electrophoresis system. Conclusion The two-dimensional gel electrophoresis system for rat cortex mitochondria was successfully established , which provides a theoretical basis and a technical support for research of cerebral cortex mitochondrion pro -teins in diseases.%目的 构建稳定的大鼠皮层线粒体双向凝胶电泳体系.方法 SD大鼠在规定的时间内快速断头取脑,冰上分离大脑皮层组织,两次密度梯度离心纯化线粒体.利用双向凝胶电泳技术改良等电聚焦的电压在3 500V聚焦,总伏小时固定为14 000 Vh.以12%的SDS-PAGE进行第二向电泳,银染显色.结果得到了分辨率较高的皮层线粒体蛋白双向凝胶电泳图谱.结论 利用改进的方法构建了高质量的双向电泳图谱,为各种疾病状态下皮层线粒体差异蛋白的研究提供了实验基础.

  5. Design of Frame-transferred Surface Array CCD Imaging System for Dark Objects

    Science.gov (United States)

    Zhang, Yu-heng; Yan, Yi-hua

    2016-01-01

    In order to realize the requirement of low-noise observations of dark objects in deep-space explorations, the design method for a simple and stable space camera imaging system is proposed in this paper. Based on the back-illuminated frame-transferred surface array CCD (CCD47-20AIMO) produced by the British E2V company, the circuitry design is given for the every part of the system. In which the applications of the correlated double-sampling analog-digital converter (AD) and the synchronous dynamic random access memory (SDRAM) can effectively suppress the correlated noise in the image signal. In addition, a drive control method favorable to the adjustment of exposure time is proposed, in the light-sensing stage it provides the exposure time with an independent and adjustable time delay to make the imaging system satisfy the requirement of long exposure time setting. The imaging system adopts the Cyclone III-series EP3C25Q240C8 field programable gate array produced by the Altera company as the kernel control device, and the drives are programmed in modules according to the function of the every device, in favor of transplantation. The simulative and experimental results indicate that the drive circuitry works normally, and that the system design can satisfy the preset requirement.

  6. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA)

    Science.gov (United States)

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  7. Design and Application of Wuhan Ionospheric Oblique Backscattering Sounding System with the Addition of an Antenna Array (WIOBSS-AA).

    Science.gov (United States)

    Cui, Xiao; Chen, Gang; Wang, Jin; Song, Huan; Gong, Wanlin

    2016-01-01

    The Wuhan Ionospheric Oblique Backscattering Sounding System with the addition of an antenna array (WIOBSS-AA) is the newest member of the WIOBSS family. It is a multi-channel radio system using phased-array antenna technology. The transmitting part of this radio system applies an array composed of five log-periodic antennas to form five beams that span an area to the northwest of the radar site. The hardware and the antenna array of the first multi-channel ionosonde in the WIOBSS family are introduced in detail in this paper. An ionospheric detection experiment was carried out in Chongyang, Hubei province, China on 16 March 2015 to examine the performance of WIOBSS-AA. The radio system demonstrated its ability to obtain ionospheric electron density information over a wide area. The observations indicate that during the experiment, the monitored large-area ionospheric F2-layer was calm and electron density increased with decreasing latitude. PMID:27314360

  8. Signal-Conditioning Block of a 1 × 200 CMOS Detector Array for a Terahertz Real-Time Imaging System

    OpenAIRE

    Jong-Ryul Yang; Woo-Jae Lee; Seong-Tae Han

    2016-01-01

    A signal conditioning block of a 1 × 200 Complementary Metal-Oxide-Semiconductor (CMOS) detector array is proposed to be employed with a real-time 0.2 THz imaging system for inspecting large areas. The plasmonic CMOS detector array whose pixel size including an integrated antenna is comparable to the wavelength of the THz wave for the imaging system, inevitably carries wide pixel-to-pixel variation. To make the variant outputs from the array uniform, the proposed signal conditioning block cal...

  9. Backward Reachability of Array-based Systems by SMT solving: Termination and Invariant Synthesis

    CERN Document Server

    Ghilardi, Silvio

    2010-01-01

    The safety of infinite state systems can be checked by a backward reachability procedure. For certain classes of systems, it is possible to prove the termination of the procedure and hence conclude the decidability of the safety problem. Although backward reachability is property-directed, it can unnecessarily explore (large) portions of the state space of a system which are not required to verify the safety property under consideration. To avoid this, invariants can be used to dramatically prune the search space. Indeed, the problem is to guess such appropriate invariants. In this paper, we present a fully declarative and symbolic approach to the mechanization of backward reachability of infinite state systems manipulating arrays by Satisfiability Modulo Theories solving. Theories are used to specify the topology and the data manipulated by the system. We identify sufficient conditions on the theories to ensure the termination of backward reachability and we show the completeness of a method for invariant sy...

  10. Application of Field Programmable Gate Arrays in Instrumentation and Control Systems of Nuclear Power Plants

    International Nuclear Information System (INIS)

    Field programmable gate arrays (FPGAs) are gaining increased attention worldwide for application in nuclear power plant (NPP) instrumentation and control (I&C) systems, particularly for safety and safety related applications, but also for non-safety ones. NPP operators and equipment suppliers see potential advantages of FPGA based digital I&C systems as compared to microprocessor based applications. This is because FPGA based systems can be made simpler, more testable and less reliant on complex software (e.g. operating systems), and are easier to qualify for safety and safety related applications. This publication results from IAEA consultancy meetings covering the various aspects, including design, qualification, implementation, licensing, and operation, of FPGA based I&C systems in NPPs

  11. The Effect of Mutual Coupling on a High Altitude Platform Diversity System Using Compact Antenna Arrays

    Directory of Open Access Journals (Sweden)

    Tommy Hult

    2010-01-01

    Full Text Available We analyze the destructive effects of mutual coupling and spatial correlation between the separate antenna elements on a combined diversity system consisting of multiple HAPs (High-Altitude Platforms employing various compact MIMO (Multiple-Input Multiple-Output antenna array configurations, in order to enhance the mutual information in HAP communication links. In addition, we assess the influence of the separation angle between HAPs on system performance, and determine the optimal separation angles that maximize the total mutual information of the system for various compact MIMO antennas. Simulation results show that although the mutual information is degraded by mutual coupling and spatial correlation, the proposed HAP diversity system still provides better performance compared to a nondiversity system for all tested scenarios.

  12. A compact system for single site atom loading of a neutral atom qubit array

    Science.gov (United States)

    Dinardo, Brad; Hughes, Steven; McBride, Sterling; Michalchuk, Joey; Anderson, Dana Z.

    2015-05-01

    We present progress towards single atom loading from a magneto optical trap reservoir to a bottle beam (BoB) array trap site for use in quantum computation. Our procedure involves vertically transporting cesium atoms via a moving molasses MOT from a 3D MOT chamber into a six sided, AR-coated, high optical access UHV science chamber. The cesium atoms are to be horizontally displaced 100 μm to a 7 × 7 array of blue-detuned BoB traps. Displacement of the atoms will be accomplished by means of a moving standing wave dipole trap. The single-site loading experiment will take place in the Atomic Qubit Array Cell (AQuA Cell) which is a compact, high performance UHV system that utilizes new miniature silicon and glass ion pump technology. The entire AQuA Cell is 0.6 liters. The cell, cooling, and transport optomechanics is incorporated in a package occupying about 0.028 cubic meters. Funding provided by IARPA MQCO.

  13. Single-feed superconducting circularly polarized microstrip array antenna for direct-to-home receiving system

    International Nuclear Information System (INIS)

    Single-feed circularly polarized microstrip patch and patch array antennas for 'direct-to-home' receiving system at around 12 GHz are studied by theoretical analysis and experiments. A full-wave microwave circuit simulator (Em), based on the method of moments and capable of handling the microwave surface impedance, has been used in the theoretical analysis of the antennas. Antennas have been fabricated from both normal conductor (gold) and YBa2Cu3O7-x (YBCO) superconductor for comparison. Measured results on resonant frequency (fr), return loss, gain, bandwidth, and axial ratio are presented. The antennas are found to show a very low axial ratio and a moderate bandwidth. In the comparison of gain, the superconducting antennas showed a remarkable improvement over their gold counterparts. The receiving power of a four-element array fabricated from a single-side YBCO thin film on (100) MgO single crystal substrate is found to be 1.8 dB higher than that of a gold array with identical configuration and both measured at 77 K. (author)

  14. Single-feed superconducting circularly polarized microstrip array antenna for direct-to-home receiving system

    Energy Technology Data Exchange (ETDEWEB)

    Ali, M.I.; Ehata, K.; Ohshima, S. [Faculty of Engineering, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510 (Japan)

    2000-07-01

    Single-feed circularly polarized microstrip patch and patch array antennas for 'direct-to-home' receiving system at around 12 GHz are studied by theoretical analysis and experiments. A full-wave microwave circuit simulator (Em), based on the method of moments and capable of handling the microwave surface impedance, has been used in the theoretical analysis of the antennas. Antennas have been fabricated from both normal conductor (gold) and YBa{sub 2}Cu{sub 3}O{sub 7-x} (YBCO) superconductor for comparison. Measured results on resonant frequency (f{sub r}), return loss, gain, bandwidth, and axial ratio are presented. The antennas are found to show a very low axial ratio and a moderate bandwidth. In the comparison of gain, the superconducting antennas showed a remarkable improvement over their gold counterparts. The receiving power of a four-element array fabricated from a single-side YBCO thin film on (100) MgO single crystal substrate is found to be 1.8 dB higher than that of a gold array with identical configuration and both measured at 77 K. (author)

  15. Cell-based drug combination screening with a microfluidic droplet array system.

    Science.gov (United States)

    Du, Guan-Sheng; Pan, Jian-Zhang; Zhao, Shi-Ping; Zhu, Ying; den Toonder, Jaap M J; Fang, Qun

    2013-07-16

    We performed cell-based drug combination screening using an integrated droplet-based microfluidic system based on the sequential operation droplet array (SODA) technique. In the system, a tapered capillary connected with a syringe pump was used for multistep droplet manipulations. An oil-covered two-dimensional droplet array chip fixed in an x-y-z translation stage was used as the platform for cell culture and analysis. Complex multistep operations for drug combination screening involving long-term cell culture, medium changing, schedule-dependent drug dosage and stimulation, and cell viability testing were achieved in parallel in the semiopen droplet array, using multiple droplet manipulations including liquid metering, aspirating, depositing, mixing, and transferring. Long-term cell culture as long as 11 days was performed in oil-covered 500 nL droplets by changing the culture medium in each droplet every 24 h. The present system was applied in parallel schedule-dependent drug combination screening for A549 nonsmall lung cancer cells with the cell cycle-dependent drug flavopiridol and two anticancer drugs of paclitaxel and 5-fluorouracil. The highest inhibition efficiency was obtained with a schedule combination of 200 nM flavopiridol followed by 100 μM 5-fluorouracil. The drug consumption for each screening test was substantially decreased to 5 ng-5 μg, corresponding to 10-1000-fold reductions compared with traditional drug screening systems with 96-well or 384-well plates. The present work provides a novel and flexible droplet-based microfluidic approach for performing cell-based screening with complex and multistep operation procedures. PMID:23786644

  16. Signal Detection of Multi-Channel Capillary Electrophoresis Chip Based on CCD

    Science.gov (United States)

    Lv, Hongfeng; Yan, Weiping; Yang, Xiaobo; Li, Jiechao; Zhu, Jieying

    2012-12-01

    A kind of multi-channel capillary electrophoresis (CE) chip signal detection system based on CCD was developed. The output signal of the CCD sensor was processed by a series of pre-processing circuits and ADC, and then it was collected by the Field Programmable Gate Array (FPGA) chip which communicated with a host computer. The core in FPGA was designed to control the signal flow of the CCD and transfer the data to PC based on a Nios II embedded soft-processor. The application of PC was used to store the data and demonstrate the curve. The measurement of the fluorescent signals for different concentration Rhodamine B dyes is presented and the comparison with other detection systems is also discussed.

  17. A new active array MST radar system with enhanced capabilities for high resolution atmospheric observations

    Science.gov (United States)

    Durga rao, Meka; Jayaraman, Achuthan; Patra, Amit; Venkat Ratnam, Madineni; Narayana Rao, T.; Kamaraj, Pandian; Jayaraj, Katta; Kmv, Prasad; Kamal Kumar, J.; Raghavendra, J.; Prasad, T. Rajendra; Thriveni, A.; Yasodha, Polisetti

    2016-07-01

    A new version of the 53-MHz MST Radar, using the 1024 solid state Transmit-Receive Modules (TRM), necessary feeder network, multi-channel receiver and a modified radar controller has been established using the existing antenna array of 1024 crossed Yagis. The new system has been configured for steering the beam on a pulse-to-pulse basis in all 360o azimuth and 20o zenith angle, providing enhanced capability to study the Mesosphere-Stratosphere-Troposphere and Ionosphere. The multi channel receiver system has been designed for Spaced Antenna (SA) and Interferometry/ Iamging applications. The new system has also been configured for radiating in circular polarization for its application in the Ionosphere Incoherent Scatter mode. The new active array MST radar at Very-High-Frequency (53-MHz) located at Gadanki (13.45°N, 79.18°E), a tropical station in India, will be used to enhance the observations of winds, turbulence during the passage of convective events over the radar site as deep convection occurs very often at tropical latitudes. The new configuration with enhanced average power, beam agility with multi-channel experiments will be a potential source for studying middle atmosphere and ionosphere. In this paper, we present the system configuration, new capabilities and the first results obtained using the new version of the MST Radar.

  18. Computationally Efficient Blind Code Synchronization for Asynchronous DS-CDMA Systems with Adaptive Antenna Arrays

    Directory of Open Access Journals (Sweden)

    Chia-Chang Hu

    2005-04-01

    Full Text Available A novel space-time adaptive near-far robust code-synchronization array detector for asynchronous DS-CDMA systems is developed in this paper. There are the same basic requirements that are needed by the conventional matched filter of an asynchronous DS-CDMA system. For the real-time applicability, a computationally efficient architecture of the proposed detector is developed that is based on the concept of the multistage Wiener filter (MWF of Goldstein and Reed. This multistage technique results in a self-synchronizing detection criterion that requires no inversion or eigendecomposition of a covariance matrix. As a consequence, this detector achieves a complexity that is only a linear function of the size of antenna array (J, the rank of the MWF (M, the system processing gain (N, and the number of samples in a chip interval (S, that is, 𝒪(JMNS. The complexity of the equivalent detector based on the minimum mean-squared error (MMSE or the subspace-based eigenstructure analysis is a function of 𝒪((JNS3. Moreover, this multistage scheme provides a rapid adaptive convergence under limited observation-data support. Simulations are conducted to evaluate the performance and convergence behavior of the proposed detector with the size of the J-element antenna array, the amount of the L-sample support, and the rank of the M-stage MWF. The performance advantage of the proposed detector over other DS-CDMA detectors is investigated as well.

  19. MicroArray Facility: a laboratory information management system with extended support for Nylon based technologies

    Directory of Open Access Journals (Sweden)

    Beaudoing Emmanuel

    2006-09-01

    Full Text Available Abstract Background High throughput gene expression profiling (GEP is becoming a routine technique in life science laboratories. With experimental designs that repeatedly span thousands of genes and hundreds of samples, relying on a dedicated database infrastructure is no longer an option. GEP technology is a fast moving target, with new approaches constantly broadening the field diversity. This technology heterogeneity, compounded by the informatics complexity of GEP databases, means that software developments have so far focused on mainstream techniques, leaving less typical yet established techniques such as Nylon microarrays at best partially supported. Results MAF (MicroArray Facility is the laboratory database system we have developed for managing the design, production and hybridization of spotted microarrays. Although it can support the widely used glass microarrays and oligo-chips, MAF was designed with the specific idiosyncrasies of Nylon based microarrays in mind. Notably single channel radioactive probes, microarray stripping and reuse, vector control hybridizations and spike-in controls are all natively supported by the software suite. MicroArray Facility is MIAME supportive and dynamically provides feedback on missing annotations to help users estimate effective MIAME compliance. Genomic data such as clone identifiers and gene symbols are also directly annotated by MAF software using standard public resources. The MAGE-ML data format is implemented for full data export. Journalized database operations (audit tracking, data anonymization, material traceability and user/project level confidentiality policies are also managed by MAF. Conclusion MicroArray Facility is a complete data management system for microarray producers and end-users. Particular care has been devoted to adequately model Nylon based microarrays. The MAF system, developed and implemented in both private and academic environments, has proved a robust solution for

  20. Design of novel digital reactor protection system based on field programmable gate array

    International Nuclear Information System (INIS)

    A novel design of reactor protection system (RPS) based on field programmable gate array (FPGA) is introduced. It is aided by micro-controller to achieve a kind of device diversity. The 2-out-of-3 voting mechanism is applied. FPGA modules perform the primary protection functions to accelerate the response speed, and avoid the common-mode-failures in software programming. Micro-controllers are able to enhance the communication ability and man-machine interface (MMI), they also accomplish the secondary protection functions

  1. Information theory analysis of sensor-array imaging systems for computer vision

    Science.gov (United States)

    Huck, F. O.; Fales, C. L.; Park, S. K.; Samms, R. W.; Self, M. O.

    1983-01-01

    Information theory is used to assess the performance of sensor-array imaging systems, with emphasis on the performance obtained with image-plane signal processing. By electronically controlling the spatial response of the imaging system, as suggested by the mechanism of human vision, it is possible to trade-off edge enhancement for sensitivity, increase dynamic range, and reduce data transmission. Computational results show that: signal information density varies little with large variations in the statistical properties of random radiance fields; most information (generally about 85 to 95 percent) is contained in the signal intensity transitions rather than levels; and performance is optimized when the OTF of the imaging system is nearly limited to the sampling passband to minimize aliasing at the cost of blurring, and the SNR is very high to permit the retrieval of small spatial detail from the extensively blurred signal. Shading the lens aperture transmittance to increase depth of field and using a regular hexagonal sensor-array instead of square lattice to decrease sensitivity to edge orientation also improves the signal information density up to about 30 percent at high SNRs.

  2. Phototherapeutic treatment of patients with peripheral nervous system diseases by means of LED arrays

    Science.gov (United States)

    Zharov, Vladimir P.; Kalinin, Konstantin L.; Menyaev, Yulian A.; Zmievskoy, Gregory N.; Savin, Alexei A.; Stulin, Igor D.; Shihkerimov, Raphiz K.; Shapkina, Alla V.; Velsher, Leonid Z.; Stakhanov, Mikhail L.

    2001-05-01

    The further development of new method of phototherapy based on use of light-emitting diodes (LED) arrays has been presented. LEDs array distribution is side of cylindrical surface, covering pathology region, was used for treatment group of patients with an affected peripheral nervous system. The main group consisted of patients with humeral plexopathy - one of possible neurological manifestation of postmastectomic syndrome as result of breast cancer radical treatment. This disease was accompanied also by some other peripheral nervous system diseases: diabetic polyneuropathy, compression ischemic mononeuropathy, festering wounds and others. The phototherapeutic method is just directed on improvement of patient's conditions in combination with other traditional methods of treatment. The main parameters of photomatrix therapeutic system: wavelength - 660 nm, line width - no more than 20 nm, intensity of radiation on the surface of edema - 0.5-3 mW/cm2 (in dependence of apparatuses type). To control and study efficiency of phototreatment ultrasonic dopplerography, thermography, electromyography and viscosimetry have been used.

  3. Lightweight Inflatable Solar Array: Providing a Flexible, Efficient Solution to Space Power Systems for Small Spacecraft

    Science.gov (United States)

    Johnson, Les; Fabisinski, Leo; Justice, Stefanie

    2014-01-01

    Affordable and convenient access to electrical power is critical to consumers, spacecraft, military and other applications alike. In the aerospace industry, an increased emphasis on small satellite flights and a move toward CubeSat and NanoSat technologies, the need for systems that could package into a small stowage volume while still being able to power robust space missions has become more critical. As a result, the Marshall Space Flight Center's Advanced Concepts Office identified a need for more efficient, affordable, and smaller space power systems to trade in performing design and feasibility studies. The Lightweight Inflatable Solar Array (LISA), a concept designed, prototyped, and tested at the NASA Marshall Space Flight Center (MSFC) in Huntsville, Alabama provides an affordable, lightweight, scalable, and easily manufactured approach for power generation in space or on Earth. This flexible technology has many wide-ranging applications from serving small satellites to soldiers in the field. By using very thin, ultraflexible solar arrays adhered to an inflatable structure, a large area (and thus large amount of power) can be folded and packaged into a relatively small volume (shown in artist rendering in Figure 1 below). The proposed presentation will provide an overview of the progress to date on the LISA project as well as a look at its potential, with continued development, to revolutionize small spacecraft and portable terrestrial power systems.

  4. Development of an Experimental Phased Array Feed System and Algorithms for Radio Astronomy

    Science.gov (United States)

    Landon, Jonathan C.

    . Results are given for simulated and experimental data, demonstrating deeper beampattern nulls by 6 to 30dB. To increase the system bandwidth toward the hundreds of MHz bandwidth required by astronomers for a fully science-ready instrument, an FPGA digital backend is introduced using a 64-input analog-to-digital converter running at 50 Msamp/sec and the ROACH processing board developed at the University of California, Berkeley. International efforts to develop digital back ends for large antenna arrays are considered, and a road map is proposed for development of a hardware correlator/beamformer at BYU using three ROACH boards communicating over 10 gigabit Ethernet.

  5. The in-capillary DPPH-capillary electrophoresis-the diode array detector combined with reversed-electrode polarity stacking mode for screening and quantifying major antioxidants in Cuscuta chinensis Lam.

    Science.gov (United States)

    Liu, Jiao; Tian, Ji; Li, Jin; Azietaku, John Teye; Zhang, Bo-Li; Gao, Xiu-Mei; Chang, Yan-Xu

    2016-07-01

    An in-capillary 2, 2-diphenyl-1-picrylhydrazyl (DPPH)-CE-the DAD (in-capillary DPPH-CE-DAD) combined with reversed-electrode polarity stacking mode has been developed to screen and quantify the active antioxidant components of Cuscuta chinensis Lam. The operation parameters were optimized with regard to the pH and concentration of buffer solution, SDS, β-CDs, organic modifier, as well as separation voltage and temperature. Six antioxidants including chlorogenic acid, p-coumaric acid, rutin, hyperin, isoquercitrin, and astragalin were screened and the total antioxidant activity of the complex matrix was successfully evaluated based on the decreased peak area of DPPH by the established DPPH-CE-DAD method. Sensitivity was enhanced under reversed-electrode polarity stacking mode and 10- to 31-fold of magnitude improvement in detection sensitivity for each analyte was attained. The results demonstrated that the newly established in-capillary DPPH-CE-DAD method combined with reversed-electrode polarity stacking mode could integrate sample concentration, the oxidizing reaction, separation, and detection into one capillary to fully automate the system. It was considered a suitable technique for the separation, screening, and determination of trace antioxidants in natural products. PMID:26955793

  6. Ultra-broadband IF/LO system of NTU W-band interferometer array

    Science.gov (United States)

    Teng, Hsiao-Feng; Wu, Jing-Cheng; Li, Huan-Hsin; Chiueh, Tzi-Hong; Niu, Dou-Chih; Hu, Robert

    2010-07-01

    NTU-Array is designed for W-band (78-113Ghz) interferometric observations of Sunyaev-Zeldovich effects. The first phase operation of the telescope with 6 receivers had its first light in 2008 with single-polarization and half the full bandwidth. The second-phase operation of NTU-Array in Nevada will begin the dual-polarization, full-band observation in 2010. One-bit sampling at 18Ghz and digital correlation are in use in this telescope. Due to the ultra broadband coverage, the IF system divides the 35GHz full-band into four 8.7GHz sub-bands. The first stage of IF module containing a 35GHz broadband amplifier with fairly flat-gain performance over 25db gain divides the first-stage IF into two outputs. The 2nd-stage IF module further divides the two input IF signals and down-converts them to four basebands of DC-8.7Ghz. An LO module with 8.7Ghz input is to generate outputs with x2, x3 and x9 harmonics for the down-conversion. The Walsh function is injected into the x9 LO via an IQ mixer. Each IF baseband is transmitted through an optical link to the 18Ghz, 1-bit sampling ADC located in the control room. The analog optical link contains a driver and equalizer to compensate for the path loss. Considering the limited size of the telescope mount, the entire IF/LO system of each receiver has a compact size about 20cm cubed. This physical size can be further reduced to fit the future 19-pixel-receiver upgrade of NTU-Array

  7. Microfluidic free-flow electrophoresis for proteomics-on-a-chip

    OpenAIRE

    Kohlheyer, Dietrich

    2008-01-01

    A new free-flow electrophoresis microchip with integrated permeable membranes was developed, and different substances were separated by free-flow zone electrophoresis, free-flow isoelectric focusing and free-flow field step electrophoresis. This chip contained a new type of membranes enabling a stable carrier flow with a perpendicular electrical current. Due to this chip configuration, the device performance and efficiency were superior to recenty published alternative systems in terms of sep...

  8. Photonic Routing Systems Using All-optical, Hybrid Integrated Wavelength Converter Arrays

    Directory of Open Access Journals (Sweden)

    Leontios Stampoulidis

    2010-02-01

    Full Text Available The integration of a new generation of all-optical wavelength converters within European project ISTMUFINS has enabled the development of compact and multi-functional photonic processing systems. Here we present the realization of demanding functionalities required in high-capacity photonic routers using these highly integrated components including: Clock recovery, data/label recovery, wavelength routing and contention resolution; all implemented with multi-signal processing using a single photonic chip – a quadruple array of SOAMZI wavelength converters which occupies a chip area of only 15 x 58 mm2. In addition, we present the capability of the technology to build WDM signal processing systems with the simultaneous operation of four quad devices in a four wavelength burst-mode regenerator. Finally, the potential of the technology to provide photonic systems-onchip is demonstrated with the first hybrid integrated alloptical burst-mode receiver prototype.

  9. A VMEbus based data acquisition system for a multi-element detector array

    International Nuclear Information System (INIS)

    A data acquisition system based on VME standard modules has been designed for MULTICS, a multi-element detector array. The system is composed of a master crate housing CPUs, Memories, Interface and Pattern boards. Up to 15 VME slave crates can be connected using the VMV vertical bus for ADC and TDC boards. A Macintosh Quadra is used as a console to provide a user friendly environment to send commands to the CPUs. Tools in the system include collecting and storing data, displaying histograms, handling all hardware parameters (high and low thresholds, rise time protection etc.). Diagnostic functions and error messages are also available to detect hardware failures or incorrect settings for the modules

  10. Effects of Spatial Characteristics on Smart Antenna System with Uniform Linear Antenna Array

    Institute of Scientific and Technical Information of China (English)

    CAO Wei-feng; WANG Wen-bo

    2005-01-01

    The effect of the spatial characteristics of antenna array on smart antenna systems can not be neglected. In the paper, the relation between spatial correlation and inter-antenna distance, impinging angle, angle spread is first investigated. With the same beamforming algorithm, we simulate the performance of smart antenna system with different Angle Spread (AS) values on the conditions of ideal and real Angle of Arrival (AOA) estimation. The results show that with the ideal AOA estimation, the AOA is enough accurate to guarantee that the system only has little performance degradation even in the case of 20 degreee AS value while the real AOA estimation influenced by channel environment degrades the performance very obviously, up to about 7 dB.

  11. MIXED EVOLUTIONARY TECHNIQUES TO REDUCE ORDER OF LINEAR INTERVAL SYSTEMS USING GENERLIZED ROUTH ARRAY

    Directory of Open Access Journals (Sweden)

    DEVENDER KUMAR SAINI

    2010-10-01

    Full Text Available Recently, genetic algorithms (GA and particle swarm optimization (PSO technique have attracted considerable attention among various modern heuristic optimization techniques. In this paper both PSO and GA optimization are employed for finding stable reduced order models of large-scale linear Interval systems. Both the techniques guarantee stability of reduced order model if the original high order model is stable. In both methods interval arithmetic is used to construct generalized Routh array for determining the denominator polynomials of reduced system. The reduced numerator polynomials are determined by minimizing Integral Square Error (ISE between original and reduced system using GA in first technique and using PSO in second technique pertaining to a unit step input. Both techniques are simple rugged and computer oriented. Both the methods are illustrated through a numerical example and the results are compared with recently published conventional model reduction technique.

  12. End-pumped coupling system based on large-aperture laser diode array

    International Nuclear Information System (INIS)

    In order to meet the pump power density requirements of room-temperature Yb: YAG laser amplifier, a coupling system of high contraction coefficient has been designed. Laser diode (LD) arrays of 80 kW output power are arranged to be spherical. Orthogonal cylindrical lenses and a hollow duct are used for pump-coupling according to luminescence properties of LD. The contraction coefficient is up to 86:1. Simulations show that the coupling efficiency of the coupling system depends weakly on the reflectivity of the reflectors of the hollow duct. The pump light can transport over a distance of at least 8.5 mm with its shape maintained. The coupling system can meet the requirements of the end-pumped room-temperature Yb: YAG slab amplifier. (authors)

  13. Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Level

    Directory of Open Access Journals (Sweden)

    Riggio Cristina

    2009-01-01

    Full Text Available Abstract In this article, a carbon nanotube (CNT array-based system combined with a polymer thin film is proposed as an effective drug release device directly at cellular level. The polymeric film embedded in the CNT array is described and characterized in terms of release kinetics, while in vitro assays on PC12 cell line have been performed in order to assess the efficiency and functionality of the entrapped agent (neural growth factor, NGF. PC12 cell differentiation, following incubation on the CNT array embedding the alginate delivery film, demonstrated the effectiveness of the proposed solution. The achieved results indicate that polymeric technology could be efficiently embedded in CNT array acting as drug delivery system at cellular level. The implication of this study opens several perspectives in particular in the field of neurointerfaces, combining several functions into a single platform.

  14. 915 MHz phased-array system for treating tumors on cylindrical structures

    International Nuclear Information System (INIS)

    A phased-array system using four 915 MHz square applicators (13 x 13 cm) previously developed in the author's laboratory was tested for heating both deep and superficial tumors of cylindrical structures such as arms, legs, or neck. Theoretical calculations using a superposition of four plane waves incident on a cylindrical tissue were conducted. The SAR patterns in the cylinder can be controlled by changing the orientation of the E field (either parallel) or perpendicular to the axis of the cylinder), and the phase and amplitude of the incident waves from each applicator. Experimental verifications using phantom tissues and a digitized computer thermographic system show good agreement. Longer sections of cylindrical structures such as an entire arm or leg can be treated by placing two groups of four applicators in series. The whole array of applicators were mounted on a mechanical oscillator driven back and forth along the arm or leg to smooth out nonuniform heating along its axis. Similar considerations were also given toward theoretical calculations and experimental verifications of this arrangement

  15. Integrated Antenna/Solar Array Cell (IA/SAC) System for Flexible Access Communications

    Science.gov (United States)

    Lee, Ricard Q.; Clark, Eric B.; Pal, Anna Maria T.; Wilt, David M.; Mueller, Carl H.

    2004-01-01

    Present satellite communications systems normally use separate solar cells and antennas. Since solar cells generally account for the largest surface area of the spacecraft, co-locating the antenna and solar cells on the same substrate opens the possibility for a number of data-rate-enhancing communications link architecture that would have minimal impact on spacecraft weight and size. The idea of integrating printed planar antenna and solar array cells on the same surface has been reported in the literature. The early work merely attempted to demonstrate the feasibility by placing commercial solar cells besides a patch antenna. Recently, Integrating multiple antenna elements and solar cell arrays on the same surface was reported for both space and terrestrial applications. The application of photovoltaic solar cell in a planar antenna structure where the radiating patch antenna is replaced by a Si solar cell has been demonstrated in wireless communication systems (C. Bendel, J. Kirchhof and N. Henze, 3rd Would Photovotaic Congress, Osaka, Japan, May 2003). Based on a hybrid approach, a 6x1 slot array with circularly polarized crossdipole elements co-located on the same surface of the solar cells array has been demonstrated (S. Vaccaro, J. R. Mosig and P. de Maagt, IEEE Trans. Ant. and Propag., Vol. 5 1, No. 8, Aug. 2003). Amorphous silicon solar cells with about 5-10% efficiency were used in these demonstrations. This paper describes recent effort to integrate advanced solar cells with printed planar antennas. Compared to prior art, the proposed WSAC concept is unique in the following ways: 1) Active antenna element will be used to achieve dynamic beam steering; 2) High efficiency (30%) GaAs multi-junction solar cells will be used instead of Si, which has an efficiency of about 15%; 3) Antenna and solar cells are integrated on a common GaAs substrate; and 4) Higher data rate capability. The IA/SAC is designed to operate at X-band (8-12 GH) and higher frequencies

  16. Nano-based chemical sensor array systems for uninhabited ground and airborne vehicles

    Science.gov (United States)

    Brantley, Christina; Ruffin, Paul B.; Edwards, Eugene

    2009-03-01

    In a time when homemade explosive devices are being used against soldiers and in the homeland security environment, it is becoming increasingly evident that there is an urgent need for high-tech chemical sensor packages to be mounted aboard ground and air vehicles to aid soldiers in determining the location of explosive devices and the origin of bio-chemical warfare agents associated with terrorist activities from a safe distance. Current technologies utilize relatively large handheld detection systems that are housed on sizeable robotic vehicles. Research and development efforts are underway at the Army Aviation & Missile Research, Development, and Engineering Center (AMRDEC) to develop novel and less expensive nano-based chemical sensors for detecting explosives and chemical agents used against the soldier. More specifically, an array of chemical sensors integrated with an electronics control module on a flexible substrate that can conform to and be surface-mounted to manned or unmanned vehicles to detect harmful species from bio-chemical warfare and other explosive devices is being developed. The sensor system under development is a voltammetry-based sensor system capable of aiding in the detection of any chemical agent and in the optimization of sensor microarray geometry to provide nonlinear Fourier algorithms to characterize target area background (e.g., footprint areas). The status of the research project is reviewed in this paper. Critical technical challenges associated with achieving system cost, size, and performance requirements are discussed. The results obtained from field tests using an unmanned remote controlled vehicle that houses a CO2/chemical sensor, which detects harmful chemical agents and wirelessly transmits warning signals back to the warfighter, are presented. Finally, the technical barriers associated with employing the sensor array system aboard small air vehicles will be discussed.

  17. Improved Protein Arrays for Quantitative Systems Analysis of the Dynamics of Signaling Pathway Interactions

    Energy Technology Data Exchange (ETDEWEB)

    YANG, CHIN-RANG [NHLBI, NIH

    2013-12-11

    Astronauts and workers in nuclear plants who repeatedly exposed to low doses of ionizing radiation (IR, <10 cGy) are likely to incur specific changes in signal transduction and gene expression in various tissues of their body. Remarkable advances in high throughput genomics and proteomics technologies enable researchers to broaden their focus from examining single gene/protein kinetics to better understanding global gene/protein expression profiling and biological pathway analyses, namely Systems Biology. An ultimate goal of systems biology is to develop dynamic mathematical models of interacting biological systems capable of simulating living systems in a computer. This Glue Grant is to complement Dr. Boothman’s existing DOE grant (No. DE-FG02-06ER64186) entitled “The IGF1/IGF-1R-MAPK-Secretory Clusterin (sCLU) Pathway: Mediator of a Low Dose IR-Inducible Bystander Effect” to develop sensitive and quantitative proteomic technology that suitable for low dose radiobiology researches. An improved version of quantitative protein array platform utilizing linear Quantum dot signaling for systematically measuring protein levels and phosphorylation states for systems biology modeling is presented. The signals are amplified by a confocal laser Quantum dot scanner resulting in ~1000-fold more sensitivity than traditional Western blots and show the good linearity that is impossible for the signals of HRP-amplification. Therefore this improved protein array technology is suitable to detect weak responses of low dose radiation. Software is developed to facilitate the quantitative readout of signaling network activities. Kinetics of EGFRvIII mutant signaling was analyzed to quantify cross-talks between EGFR and other signaling pathways.

  18. Fast and robust control of nanopositioning systems: Performance limits enabled by field programmable analog arrays

    Science.gov (United States)

    Baranwal, Mayank; Gorugantu, Ram S.; Salapaka, Srinivasa M.

    2015-08-01

    This paper aims at control design and its implementation for robust high-bandwidth precision (nanoscale) positioning systems. Even though modern model-based control theoretic designs for robust broadband high-resolution positioning have enabled orders of magnitude improvement in performance over existing model independent designs, their scope is severely limited by the inefficacies of digital implementation of the control designs. High-order control laws that result from model-based designs typically have to be approximated with reduced-order systems to facilitate digital implementation. Digital systems, even those that have very high sampling frequencies, provide low effective control bandwidth when implementing high-order systems. In this context, field programmable analog arrays (FPAAs) provide a good alternative to the use of digital-logic based processors since they enable very high implementation speeds, moreover with cheaper resources. The superior flexibility of digital systems in terms of the implementable mathematical and logical functions does not give significant edge over FPAAs when implementing linear dynamic control laws. In this paper, we pose the control design objectives for positioning systems in different configurations as optimal control problems and demonstrate significant improvements in performance when the resulting control laws are applied using FPAAs as opposed to their digital counterparts. An improvement of over 200% in positioning bandwidth is achieved over an earlier digital signal processor (DSP) based implementation for the same system and same control design, even when for the DSP-based system, the sampling frequency is about 100 times the desired positioning bandwidth.

  19. Nonlinear waves in capillary electrophoresis

    OpenAIRE

    Ghosal, Sandip; Chen, Zhen

    2012-01-01

    Electrophoretic separation of a mixture of chemical species is a fundamental technique of great usefulness in biology, health care and forensics. In capillary electrophoresis the sample migrates in a microcapillary in the presence of a background electrolyte. When the ionic concentration of the sample is sufficiently high, the signal is known to exhibit features reminiscent of nonlinear waves including sharp concentration ‘shocks’. In this paper we consider a simplified model consisting of a ...

  20. Development of Radar Control system for Multi-mode Active Phased Array Radar for atmospheric probing

    Science.gov (United States)

    Yasodha, Polisetti; Jayaraman, Achuthan; Thriveni, A.

    2016-07-01

    Modern multi-mode active phased array radars require highly efficient radar control system for hassle free real time radar operation. The requirement comes due to the distributed architecture of the active phased array radar, where each antenna element in the array is connected to a dedicated Transmit-Receive (TR) module. Controlling the TR modules, which are generally few hundreds in number, and functioning them in synchronisation, is a huge task during real time radar operation and should be handled with utmost care. Indian MST Radar, located at NARL, Gadanki, which is established during early 90's, as an outcome of the middle atmospheric program, is a remote sensing instrument for probing the atmosphere. This radar has a semi-active array, consisting of 1024 antenna elements, with limited beam steering, possible only along the principle planes. To overcome the limitations and difficulties, the radar is being augmented into fully active phased array, to accomplish beam agility and multi-mode operations. Each antenna element is excited with a dedicated 1 kW TR module, located in the field and enables to position the radar beam within 20° conical volume. A multi-channel receiver makes the radar to operate in various modes like Doppler Beam Swinging (DBS), Spaced Antenna (SA), Frequency Domain Interferometry (FDI) etc. Present work describes the real-time radar control (RC) system for the above described active phased array radar. The radar control system consists of a Spartan 6 FPGA based Timing and Control Signal Generator (TCSG), and a computer containing the software for controlling all the subsystems of the radar during real-time radar operation and also for calibrating the radar. The main function of the TCSG is to generate the control and timing waveforms required for various subsystems of the radar. Important components of the RC system software are (i) TR module configuring software which does programming, controlling and health parameter monitoring of the

  1. Schwarzschild-Couder telescope for the Cherenkov Telescope Array: Development of the Optical System

    CERN Document Server

    Rousselle, Julien; Errando, Manel; Humensky, Brian; Mukherjee, Reshmi; Nieto, Daniel; Okumura, Akira; Vassiliev, Vladimir

    2013-01-01

    The CTA (Cherenkov Telescope Array) is the next generation ground-based experiment for very high-energy (VHE) gamma-ray observations. It will integrate several tens of imaging atmospheric Cherenkov telescopes (IACTs) with different apertures into a single astronomical instrument. The US part of the CTA collaboration has proposed and is developing a novel IACT design with a Schwarzschild-Couder (SC) aplanatic two mirror optical system. In comparison with the traditional single mirror Davies-Cotton IACT the SC telescope, by design, can accommodate a wide field-of-view, with significantly improved imaging resolution. In addition, the reduced plate scale of an SC telescope makes it compatible with highly integrated cameras assembled from silicon photo multipliers. In this submission we report on the status of the development of the SC optical system, which is part of the effort to construct a full-scale prototype telescope of this type at the Fred Lawrence Whipple Observatory in southern Arizona.

  2. Michrohole Arrays Drilled with Advanced Abrasive Slurry Jet Technology to Efficiently Exploit Enhanced Geothermal Systems

    Energy Technology Data Exchange (ETDEWEB)

    Oglesby, Kenneth [Impact Technologies, Tulsa, OK (United States); Finsterle, Stefan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Zhang, Yingqi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Pan, Lehua [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dobson, Parick [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mohan, Ram [Univ. of Tulsa, OK (United States); Shoham, Ovadia [Univ. of Tulsa, OK (United States); Felber, Betty [Impact Technologies, Tulsa, OK (United States); Rychel, Dwight [Impact Technologies, Tulsa, OK (United States)

    2014-03-12

    This project had two major areas of research for Engineered/ Enhanced Geothermal System (EGS) development - 1) study the potential benefits from using microholes (i.e., bores with diameters less than 10.16 centimeters/ 4 inches) and 2) study FLASH ASJ to drill/ install those microbores between a well and a fracture system. This included the methods and benefits of drilling vertical microholes for exploring the EGS reservoir and for installing multiple (forming an array of) laterals/ directional microholes for creating the in-reservoir heat exchange flow paths. Significant benefit was found in utilizing small microbore sized connecting bores for EGS efficiency and project life. FLASH ASJ was deemed too complicated to optimally work in such deep reservoirs at this time.

  3. The fluid mechanics of continuous flow electrophoresis

    Science.gov (United States)

    Saville, D. A.

    1990-01-01

    The overall objective is to establish theoretically and confirm experimentally the ultimate capabilities of continuous flow electrophoresis chambers operating in an environment essentially free of particle sedimentation and buoyancy. The efforts are devoted to: (1) studying the effects of particle concentration on sample conductivity and dielectric constant. The dielectric constant and conductivity were identified as playing crucial roles in the behavior of the sample and on the resolving power and throughput of continuous flow devices; and (2) improving the extant mathematical models to predict flow fields and particle trajectories in continuous flow electrophoresis. A dielectric spectrometer was designed and built to measure the complex dielectric constant of a colloidal dispersion as a function of frequency between 500 Hz and 200 kHz. The real part of the signal can be related to the sample's conductivity and the imaginary part to its dielectric constant. Measurements of the dielectric constants of several different dispersions disclosed that the dielectric constants of dilute systems of the sort encountered in particle electrophoresis are much larger than would be expected based on the extant theory. Experiments were carried out to show that, in many cases, this behavior is due to the presence of a filamentary structure of small hairs on the particle surface. A technique for producing electrokinetically ideal synthetic latex particles by heat treating was developed. Given the ubiquitous nature of hairy surfaces with both cells and synthetic particles, it was deemed necessary to develop a theory to explain their behavior. A theory for electrophoretic mobility of hairy particles was developed. Finally, the extant computer programs for predicting the structure of electro-osmotically driven flows were extended to encompass flow channels with variable wall mobilities.

  4. Water experiment on phased array acoustic leak detection system for sodium-heated steam generator

    International Nuclear Information System (INIS)

    Highlights: • An acoustic leak detection system for sodium heated steam generator is proposed. • The new system can separate leak source from steam generator background noise. • Performance of the new system has been confirmed in water experiments. - Abstract: A phased array acoustic leak detection system for sodium heated steam generator has been proposed. The major advantage of the new system is it could provide information of acoustic source direction. An acoustic source of a sodium–water reaction is supposed to be localized while the background noise of the steam generator operation is uniformly distributed in the steam generator tube region. Therefore the new system could separate the target leak source from steam generator background noise. In the previous study, the methodology was proposed and basic performance was confirmed by numerical analysis. However, in the numerical analysis, acoustic transportation through the SG tube bundle was not modeled. In the present study, performance the proposed system has been confirmed in water experiments with mockup tube bundles

  5. Combining transverse field detectors and color filter arrays to improve multispectral imaging systems.

    Science.gov (United States)

    Martínez, Miguel A; Valero, Eva M; Hernández-Andrés, Javier; Romero, Javier; Langfelder, Giacomo

    2014-05-01

    This work focuses on the improvement of a multispectral imaging sensor based on transverse field detectors (TFDs). We aimed to achieve a higher color and spectral accuracy in the estimation of spectral reflectances from sensor responses. Such an improvement was done by combining these recently developed silicon-based sensors with color filter arrays (CFAs). Consequently, we sacrificed the filter-less full spatial resolution property of TFDs to narrow down the spectrally broad sensitivities of these sensors. We designed and performed several experiments to test the influence of different design features on the estimation quality (type of sensor, tunability, interleaved polarization, use of CFAs, type of CFAs, number of shots), some of which are exclusive to TFDs. We compared systems that use a TFD with systems that use normal monochrome sensors, both combined with multispectral CFAs as well as common RGB filters present in commercial digital color cameras. Results showed that a system that combines TFDs and CFAs performs better than systems with the same type of multispectral CFA and other sensors, or even the same TFDs combined with different kinds of filters used in common imaging systems. We propose CFA+TFD-based systems with one or two shots, depending on the possibility of using longer capturing times or not. Improved TFD systems thus emerge as an interesting possibility for multispectral acquisition, which overcomes the limited accuracy found in previous studies. PMID:24921886

  6. Prototype of a production system for Cherenkov Telescope Array with DIRAC

    CERN Document Server

    Arrabito, L; Haupt, A; Graciani Diaz, R; Stagni, F; Tsaregorodtsev, A

    2015-01-01

    The Cherenkov Telescope Array (CTA) — an array of many tens of Imaging Atmospheric Cherenkov Telescopes deployed on an unprecedented scale — is the next generation instrument in the field of very high energy gamma-ray astronomy. CTA will operate as an open observatory providing data products to the scientific community. An average data stream of about 10 GB/s for about 1000 hours of observation per year, thus producing several PB/year, is expected. Large CPU time is required for data-processing as well for massive Monte Carlo simulations needed for detector calibration purposes. The current CTA computing model is based on a distributed infrastructure for the archive and the data off-line processing. In order to manage the off-line data-processing in a distributed environment, CTA has evaluated the DIRAC (Distributed Infrastructure with Remote Agent Control) system, which is a general framework for the management of tasks over distributed heterogeneous computing environments. In particular, a production sy...

  7. An Ultrasonic Imaging System Using a Matrix-Type Transducer Array

    Science.gov (United States)

    Noguchi, Michitoshi; Mizutani, Koichi; Nagai, Keinosuke; Yamashita, Yoshinari

    1999-05-01

    We propose a method for imaging an object's surface using a matrix-type transducer array. The matrix-type transducer array has a simple structure with some line-electrode fingers on both sides of a piezoelectric ceramic plate. By a combination of electrical-mechanical scanning, we image of an object's surface using data of distance between the transducer and the object. The ultrasonic probe used in the present system requires without beam forming and no signal processing for focusing. We measure two objects: one has a multilayered structure consisting of three differently sized aluminum plates, the biggest plate having an area of 150 mm × 80 mm and 0.8 1.5 mm thickness; and the other is a radio-wave-absorbent block 100.5 mm × 100.5 mm × 18.5 mm in size with 5 × 5 holes in a grid made of ferrite. The ultrasonic probe operates at a frequency of 3.5 MHz and the sensing distance between the transducer and the measured object is about 80 mm. At this distance, the diameter of the ultrasonic beam launched from the transducer is about 13 mm. We obtained a height resolution of ±0.2 mm and a spatial resolution of about 3.0 mm.

  8. Computation of strain and rotation tensor as well as their uncertainties for small arrays in spherical coordinate system

    Institute of Scientific and Technical Information of China (English)

    MENG Guo-jie; REN Jin-wei; WU Ji-cang; SHEN Xu-hui

    2008-01-01

    Based on Taylor series expansion and strain components expressions of elastic mechanics, we derive formulae of strain and rotation tensor for small arrays in spherical coordinates system. By linearization process of the formulae, we also derive expressions of strain components and Euler vector uncertainties respectively for subnets using the law of error propagation. Taking GPS velocity field in Sichuan-Yunnan area as an example, we compute dilation rate and maximum shear strain rate field using the above procedure, and their characteristics are preliminarily carried on. Limits of the strain model for small array are also discussed. We make detailed explanations on small array method and the choice of small arrays. How to set weights of GPS observations are further discussed. Moreover relationship between strain and radius of GPS subnets is also analyzed.

  9. Simulation on spatial resolution of scintillator arrays based on neutron penumbral imaging system

    International Nuclear Information System (INIS)

    In order to compare three kinds of scintillation detectors, the Monte Carlo method is introduced to calculate the spatial resolution and energy deposition of scintillator arrays with different fiber diameters. According to simulation results, the resolution of standard liquid scintillator array is better than that of plastic scintillator array, and the resolution of deuterated liquid scintillator array is almost half that of standard liquid scintillator array. The energy deposition of hydrogen-rich scintillator is higher than that of deuterated scintillator. Moreover, smaller fiber diameter leads to better spatial resolution, and thicker scintillator leads to higher energy deposition. (authors)

  10. Small-animal whole-body imaging using a photoacoustic full ring array system

    Science.gov (United States)

    Xia, Jun; Guo, Zijian; Aguirre, Andres; Zhu, Quing; Wang, Lihong V.

    2011-03-01

    In this report, we present a novel 3D photoacoustic computed tomography (PACT) system for small-animal whole-body imaging. The PACT system, based on a 512-element full-ring transducer array, received photoacoustic signals primarily from a 2-mm-thick slice. The light was generated by a pulse laser, and can either illuminate from the top or be reshaped to illuminate the sample from the side, using a conical lens and an optical condenser. The PACT system was capable of acquiring an in-plane image in 1.6 s; by scanning the sample in the elevational direction, a 3D tomographic image could be constructed. We tested the system by imaging a cylindrical phantom made of human hairs immersed in a scattering medium. The reconstructed image achieved an in-plane resolution of 0.1 mm and an elevational resolution of 1 mm. After deconvolution in the elevational direction, the 3D image was found to match well with the phantom. The system was also used to image a baby mouse in situ; the spinal cord and ribs can be seen easily in the reconstructed image. Our results demonstrate that the PACT system has the potential to be used for fast small-animal whole-body tomographic imaging.

  11. The application of scintillating fiber optics in a diode array digital radiography system

    International Nuclear Information System (INIS)

    This paper presents research to evaluate the use of scintillating fiber optics (SFO) to replace traditional phosphor screens as an imaging detector in a digital radiographic system. A SFO-based detector was constructed for a Diode Array Digital Radiography (DADR) system. System image quality was evaluated with five characterization criteria: spatial resolution, signal-to noise ratio (SNR), large-area contrast detectability, responsivity, and inspection task performance. It has been concluded from this evaluation that the spatial resolution, SNR and large-area contrast detectability to that observed with phosphor screens. Spatial resolution is typically 8-9 line-pairs/mm (lp/mm) for SFO, while the phosphor screen resolution typically 2-6 lp/mm. However, responsivity (i.e., the system sensitivity), with SFO is much lower than measured with phosphor screens. In this energy range, although the x-ray absorption efficiency of SFO is high, the overall efficiency is low than for phosphor screens. By adjusting the gains of an image intensifier and an electronic amplifier, and adequately large signal output for a feasible x-ray dose input was obtained with the SFO system. The SFO system has produced images of electronic assemblies and met the requirements of the ASTM 801E No. 4. The experimental results indicate that the SFO detector is comparable to phosphor screens at low x-ray energies (p)

  12. In vivo visualization of robotically implemented synthetic tracked aperture ultrasound (STRATUS) imaging system using curvilinear array

    Science.gov (United States)

    Zhang, Haichong K.; Aalamifar, Fereshteh; Boctor, Emad M.

    2016-04-01

    Synthetic aperture for ultrasound is a technique utilizing a wide aperture in both transmit and receive to enhance the ultrasound image quality. The limitation of synthetic aperture is the maximum available aperture size limit determined by the physical size of ultrasound probe. We propose Synthetic-Tracked Aperture Ultrasound (STRATUS) imaging system to overcome the limitation by extending the beamforming aperture size through ultrasound probe tracking. With a setup involving a robotic arm, the ultrasound probe is moved using the robotic arm, while the positions on a scanning trajectory are tracked in real-time. Data from each pose are synthesized to construct a high resolution image. In previous studies, we have demonstrated the feasibility through phantom experiments. However, various additional factors such as real-time data collection or motion artifacts should be taken into account when the in vivo target becomes the subject. In this work, we build a robot-based STRATUS imaging system with continuous data collection capability considering the practical implementation. A curvilinear array is used instead of a linear array to benefit from its wider capture angle. We scanned human forearms under two scenarios: one submerged the arm in the water tank under 10 cm depth, and the other directly scanned the arm from the surface. The image contrast improved 5.51 dB, and 9.96 dB for the underwater scan and the direct scan, respectively. The result indicates the practical feasibility of STRATUS imaging system, and the technique can be potentially applied to the wide range of human body.

  13. Nonlinear electrophoresis for purification of soil DNA for metagenomics.

    Science.gov (United States)

    Engel, Katja; Pinnell, Lee; Cheng, Jiujun; Charles, Trevor C; Neufeld, Josh D

    2012-01-01

    Purification of microbial DNA from soil is challenging due to the co-extraction of humic acids and associated phenolic compounds that inhibit subsequent cloning, amplification or sequencing. Removal of these contaminants is critical for the success of metagenomic library construction and high-throughput sequencing of extracted DNA. Using three different composite soil samples, we compared a novel DNA purification technique using nonlinear electrophoresis on the synchronous coefficient of drag alteration (SCODA) instrument with alternate purification methods such as direct current (DC) agarose gel electrophoresis followed by gel filtration or anion exchange chromatography, Wizard DNA Clean-Up System, and the PowerSoil DNA Isolation kit. Both nonlinear and DC electrophoresis were effective at retrieving high-molecular weight DNA with high purity, suitable for construction of large-insert libraries. The PowerSoil DNA Isolation kit and the nonlinear electrophoresis had high recovery of high purity DNA suitable for sequencing purposes. All methods demonstrated high consistency in the bacterial community profiles generated from the DNA extracts. Nonlinear electrophoresis using the SCODA instrument was the ideal methodology for the preparation of soil DNA samples suitable for both high-throughput sequencing and large-insert cloning applications. PMID:22056233

  14. A chemical-detecting system based on a cross-reactive optical sensor array

    Science.gov (United States)

    Dickinson, Todd A.; White, Joel; Kauer, John S.; Walt, David R.

    1996-08-01

    THE vertebrate olfactory system has long been recognized for its extraordinary sensitivity and selectivity for odours. Chemical sensors have been developed recently that are based on analogous distributed sensing properties1-4, but although an association between artificial devices and the olfactory system has been made explicit in some previous studies4,5, none has incorporated comparable mechanisms into the mode of detection. Here we describe a multi-analyte fibre-optic sensor modelled directly on the olfactory system, in the sense that complex, time-dependent signals from an array of sensors provide a 'signature' of each analyte. In our system, polymer-immobilized dye molecules on the fibre tips give different fluorescent response patterns (including spectral shifts, intensity changes, spectral shape variations6 and temporal responses) on exposure to organic vapours, depending on the physical and chemical nature (for example, polarity, shape and size) of both the vapour and the polymer. We use video images of temporal responses of the multi-fibre tip as the input signals to train a neural network for vapour recognition. The system is able to identify individual vapours at different concentrations with great accuracy. 'Artificial noses' such as this should have wide potential application, most notably in environmental and medical monitoring.

  15. A Prototype for the Cherenkov Telescope Array Pipelines Framework: Modular Efficiency Simple System (MESS)

    CERN Document Server

    ,

    2015-01-01

    The Cherenkov Telescope Array (CTA) is a ground-based $\\gamma$-ray observatory that will observe the full sky in the energy range from 20 GeV to 100 TeV from facilities in both hemispheres. It is proposed to consist of more than 100 telescopes, producing large amounts of data. Apart from the storage system, there are also requirements on the software framework to allow efficient data processing, i.e. robustness, execution speed and coding efficiency. This contribution will present a plain and simple pipeline framework design prototype for CTA that builds upon well-known tools, allowing the users to focus on physics problems without learning complicated software paradigms.

  16. Large-area, high-intensity PV arrays for systems using dish concentrating optics

    Energy Technology Data Exchange (ETDEWEB)

    Ward, J.S.; Duda, A.; Zweibel, K.; Coutts, T.J. [National Renewable Energy Lab., Golden, CO (United States)

    1998-09-01

    In this paper, the authors report on efforts to fabricate monolithic interconnected modules (MIMs) using III-V semiconductors with bandgaps appropriate for the terrestrial solar spectrum. The small size of the component cells comprising the MIM allows for operation at extremely high flux densities and relaxes the requirement for a small spot size to be generated by the optics. This makes possible a PV option for the large dish concentrator systems that have been developed by the solar thermal community for use with Stirling engines. Additionally, the highly effective back-surface reflector integrated into the MIM design is an effective tool for thermal management of the array. Development of this technology would radically alter the projections for PV manufacturing capacity because of the potential for extremely high power generation per unit area of semiconductor material.

  17. A performance analysis of multi-hop ad hoc networks with adaptive antenna array systems

    CERN Document Server

    Ali, Olfa Ben Sik; Gagnon, Francois

    2010-01-01

    Based on a stochastic geometry framework, we establish an analysis of the multi-hop spatial reuse aloha protocol (MSR-Aloha) in ad hoc networks. We compare MSR-Aloha to a simple routing strategy, where a node selects the next relay of the treated packet as to be its nearest receiver with a forward progress toward the final destination (NFP). In addition, performance gains achieved by employing adaptive antenna array systems are quantified in this paper. We derive a tight upper bound on the spatial density of progress of MSR-Aloha. Our analytical results demonstrate that the spatial density of progress scales as the square root of the density of users, and the optimal contention density (that maximizes the spatial density of progress) is independent of the density of users. These two facts are consistent with the observations of Baccelli et al., established through an analytical lower bound and through simulations.

  18. Towards a full Atmospheric Calibration system for the Cherenkov Telescope Array

    CERN Document Server

    Doro, M; Blanch, O; Font, LL; Garrido, D; Lopez-Oramas, A

    2013-01-01

    The current generation of Cherenkov telescopes is mainly limited in their gamma-ray energy and flux reconstruction by uncertainties in the determination of atmospheric parameters. The Cherenkov Telescope Array (CTA) aims to provide high-precision data extending the duty cycle as much as possible. To reach this goal, it is necessary to continuously and precisely monitor the atmosphere by means of remote-sensing devices, which are able to provide altitude-resolved and wavelength-dependent extinction factors, sensitive up to the tropopause and higher. Raman LIDARs are currently the best suited technology to achieve this goal with one single instrument. However, the synergy with other instruments like radiometers, solar and stellar photometers, all-sky cameras, and possibly radio-sondes is desirable in order to provide more precise and accurate results, and allows for weather forecasts and now-casts. In this contribution, we will discuss the need and features of such multifaceted atmospheric calibration systems.

  19. 2D-DOA and Mutual Coupling Estimation in Vehicle Communication System via Conformal Array

    Directory of Open Access Journals (Sweden)

    Yan Zou

    2015-01-01

    Full Text Available Many direction-of-arrival (DOA estimation algorithms have been proposed recently. However, the effect of mutual coupling among antenna elements has not been taken into consideration. In this paper, a novel DOA and mutual coupling coefficient estimation algorithm is proposed in intelligent transportation systems (ITS via conformal array. By constructing the spectial mutual coupling matrix (MCM, the effect of mutual coupling can be eliminated via instrumental element method. Then the DOA of incident signals can be estimated based on parallel factor (PARAFAC theory. The PARAFAC model is constructed in cumulant domain using covariance matrices. The mutual coupling coefficients are estimated based on the former DOA estimation and the matrix transformation between MCM and the steering vector. Finally, due to the drawback of the parameter pairing method in Wan et al., 2014, a novel method is given to improve the performance of parameter pairing. The computer simulation verifies the effectiveness of the proposed algorithm.

  20. Joint Angle and Delay Estimation (JADE) in Antenna Array CDMA Systems

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The estimate of signals parameters is very important in wireless communications. In this paper, we combine subspace-based blind channel estimation algorithm with the extension of the JADE-WSF algorithm to jointly estimate the Angles-of-Arrival (AOAs) and delays of multipath signals arriving at an antenna array in Code Division Multiple Access (CDMA) systems. Our approach uses a collection of estimates of a consistent chip-sample of space-time vector channel. The channel estimates are assumed to have constant path AOA and delay over a finite number of symbols. Unlike the traditional MUltiple SIgnal Classification (MUSIC) and Estimation of Signal Parameters via Rotational Invariance Techniques (ESPRIT) algorithms for the estimation of signals parameters, the proposed method can work when the number of paths exceeds the number of antennas. The Cramer-Rao Bound (CRB) and simulations are provided.

  1. A micro-pillar array to trap magnetic beads in microfluidic systems

    KAUST Repository

    Gooneratne, Chinthaka Pasan

    2012-12-01

    A micro-pillar array (MPA) is proposed in this paper to trap and separate magnetic beads (MBs) in microfluidic systems. MBs are used in many biomedical applications due to being compatible in dimension to biomolecules, the large surface area available to attach biomolecules, and the fact that they can be controlled by a magnetic field. Trapping and separating these labeled biomolecules is an important step toward achieving reliable and accurate quantification for disease diagnostics. Nickel Iron (Ni50Fe 50) micro-pillars were fabricated on a Silicon (Si) substrate by standard microfabrication techniques. Experimental results showed that MBs could be trapped on the MPA at the single bead level and separated from other non-target particles. This principle can easily be extended to trap and separate target biomolecules in heterogeneous biological samples. © 2012 IEEE.

  2. Enhancing resolution properties of array antennas via field extrapolation: application to MIMO systems

    Science.gov (United States)

    Reggiannini, Ruggero

    2015-12-01

    This paper is concerned with spatial properties of linear arrays of antennas spaced less than half wavelength. Possible applications are in multiple-input multiple-output (MIMO) wireless links for the purpose of increasing the spatial multiplexing gain in a scattering environment, as well as in other areas such as sonar and radar. With reference to a receiving array, we show that knowledge of the received field can be extrapolated beyond the actual array size by exploiting the finiteness of the interval of real directions from which the field components impinge on the array. This property permits to increase the performance of the array in terms of angular resolution. A simple signal processing technique is proposed allowing formation of a set of beams capable to cover uniformly the entire horizon with an angular resolution better than that achievable by a classical uniform-weighing half-wavelength-spaced linear array. Results are also applicable to active arrays. As the above approach leads to arrays operating in super-directive regime, we discuss all related critical aspects, such as sensitivity to external and internal noises and to array imperfections, and bandwidth, so as to identify the basic design criteria ensuring the array feasibility.

  3. Strain identification in Rhizobium by starch gel electrophoresis of isoenzymes

    DEFF Research Database (Denmark)

    Engvild, Kjeld Christensen; Nielsen, G.

    1985-01-01

    Sonieated extracts of rhizobia, especiaUy Rhizobium leguminosarum from pea and vetch, were run in horizontal starch gel electrophoresis in the cold. The rhizobia were grown on agar on a slime suppressing substrate of tryptone-yeast extract-CaCl2 with small amounts of mannitol, sorbitol and...... arabinose and other sugars as enzyme inducers. After electrophoresis the gels were separated into several slabs by a gel cutter. Each slab was stained for a particular enzyme. Among numerous enzyme systems tested we found useful variation in esterases (EC 3.1.1.1, EC 3.1.1.2), 3-hydroxybutyrate...

  4. Fabrication technology of integrated fiber microfluidic electrophoresis chip

    Institute of Scientific and Technical Information of China (English)

    LI MengChun

    2007-01-01

    The technology of PCB was used to fabricate the chip mould, and the microfluidic electrophoresis chip was fabricated with PDMS material. The fiber integrated on the chip was used as the transmission medium, so the light spot size was near the depth of microchannel. The detection sensitivity was improved, and the optical focusing system was spared. The fabrication process, sealing methods and structure characteristic of PDMS microfluidic electrophoresis chips were discussed. The experiment was achieved by using the fabricated chip to separate FITC fluorescein and FITC-labeled amino acid mixture reagent, and the feasibility of the chip was validated.

  5. RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays

    Science.gov (United States)

    Stanislaus, Romesh; Carey, Mark; Deus, Helena F; Coombes, Kevin; Hennessy, Bryan T; Mills, Gordon B; Almeida, Jonas S

    2008-01-01

    Background Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technologies, substantial amounts of analytical data are generated. Over 1000 samples may be printed on a single nitrocellulose slide. Up to 100 different proteins may be assessed using immunoperoxidase or immunoflorescence techniques in order to determine relative amounts of protein expression in the samples of interest. Results In this report an RPPA Information Management System (RIMS) is described and made available with open source software. In order to implement the proposed system, we propose a metadata format known as reverse phase protein array markup language (RPPAML). RPPAML would enable researchers to describe, document and disseminate RPPA data. The complexity of the data structure needed to describe the results and the graphic tools necessary to visualize them require a software deployment distributed between a client and a server application. This was achieved without sacrificing interoperability between individual deployments through the use of an open source semantic database, S3DB. This data service backbone is available to multiple client side applications that can also access other server side deployments. The RIMS platform was designed to interoperate with other data analysis and data visualization tools such as Cytoscape. Conclusion The proposed RPPAML data format hopes to standardize RPPA data. Standardization of data would result in diverse client applications being able to operate on the same set of data. Additionally, having data in a standard format would enable data dissemination and data analysis. PMID:19102773

  6. Potentials and Method Improvements of Capillary Zone Electrophoresis for Use in Spelt Breeding Programs

    Science.gov (United States)

    Capillary zone electrophoresis (CZE) in acidic buffer systems is capable of separating cereal storage proteins based on similar separation principles as classical acidic polyacrylamide gel electrophoresis. However, it is faster, its resolution is distinctly higher and data evaluation is much simpler...

  7. Carbon Fiber-gold/mercury Dual-electrode Detection for Capillary Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A carbon fiber-gold/mercury dual-electrode for capillary electrophoresis is constructed. Cysteine, glutathione, ascorbic acid and uric acid can be detected simultaneously and selectively at the dual-electrode, respectively. The capillary electrophoresis / dual-electrode detection system has been used to determine these compounds in human blood samples.

  8. Study of retro reflector array for the polarimeter-interferometer system on EAST Tokamak

    Science.gov (United States)

    Lan, T.; Wang, S. X.; Liu, H. Q.; Liu, J.; Jie, Y. X.; Zou, Z. Y.; Li, W. M.; Gao, X.; Qin, H.

    2015-12-01

    In this paper, we experimentally verify the feasibility of replacing individual retro reflectors (RRs) with retro reflector array (RRA) in EAST POlarimeter/INTerferometer (POINT) system, by considering mode transformation and power wastage. Being exposed to plasma environment directly, RRs have risks of deformation, erosion and deposition. RRA is preferable because it can be installed within a smaller space and provide a gap of several centimeters for the shutter design. This protective structure can reduce the cost of device maintenance and bring down system errors. According to Helmholtz-Kirchhoff integral theorem, the optimized incident diameter for the RRA, constituted by seven hexagonal RR cells, is 40 mm in POINT system. The corresponding bench tests are carried out by measuring the propagation properties of reflected beams by plane RRA for perpendicular incidence and reflected beams by terrace RRA for oblique incidence. The experimental results illustrate that RRA can be satisfactorily applied in POINT system at the optimized incident diameter. In view of the energy wastage caused by plasma film coating, it is found that RRA has more advantages for diagnostics using shorter wavelengths, such as the case in ITER.

  9. Study of retro reflector array for the polarimeter-interferometer system on EAST Tokamak

    International Nuclear Information System (INIS)

    In this paper, we experimentally verify the feasibility of replacing individual retro reflectors (RRs) with retro reflector array (RRA) in EAST POlarimeter/INTerferometer (POINT) system, by considering mode transformation and power wastage. Being exposed to plasma environment directly, RRs have risks of deformation, erosion and deposition. RRA is preferable because it can be installed within a smaller space and provide a gap of several centimeters for the shutter design. This protective structure can reduce the cost of device maintenance and bring down system errors. According to Helmholtz-Kirchhoff integral theorem, the optimized incident diameter for the RRA, constituted by seven hexagonal RR cells, is 40 mm in POINT system. The corresponding bench tests are carried out by measuring the propagation properties of reflected beams by plane RRA for perpendicular incidence and reflected beams by terrace RRA for oblique incidence. The experimental results illustrate that RRA can be satisfactorily applied in POINT system at the optimized incident diameter. In view of the energy wastage caused by plasma film coating, it is found that RRA has more advantages for diagnostics using shorter wavelengths, such as the case in ITER

  10. Electromigration dispersion in Capillary Electrophoresis

    CERN Document Server

    Chen, Zhen; 10.1007/s11538-011-9708-7

    2012-01-01

    In a previous paper (S. Ghosal and Z. Chen Bull. Math. Biol. 2010, vol. 72, pg. 2047) it was shown that the evolution of the solute concentration in capillary electrophoresis is described by a nonlinear wave equation that reduced to Burger's equation if the nonlinearity was weak. It was assumed that only strong electrolytes (fully dissociated) were present. In the present paper it is shown that the same governing equation also describes the situation where the electrolytic buffer consists of a single weak acid (or base). A simple approximate formula is derived for the dimensionless peak variance which is shown to agree well with published experimental data.

  11. Capillary electrophoresis theory and practice

    CERN Document Server

    Grossman, Paul D

    1992-01-01

    This book is designed to be a practical guide, used by wide audience, including those new to CE, those more experienced, routine users, those interested in technology development, and those involved with applications research. References have been emphasized to allow the reader to explore the detailed specifics and theoretical foundations.This book draws together the rapidly evolving, diverse, and multidisciplinary subject of capillary electrophoresis (CE). It is designed as a practical guide to be used by a wide audience, including those new to CE as well as more experienced users. T

  12. Fiber Bragg Grating Sensor Array System Based on Digital Phase Generated Carrier Demodulation and Reference Compensation Method

    Institute of Scientific and Technical Information of China (English)

    Jun He; Fang Li; Hao Xiao; Yu-Liang Liu

    2008-01-01

    A novel fiber Bragg grating (FBG) sensor array system based on digital phase generated carrier (PGC) demodulation and reference compensation method is proposed and set up. Experimental results confirm that the digital PGC demodulation can be used for wavelength-division-multiplexed FBG sensor array and the reference compensation method can reduce the environmental interference by approximately 40 dB in the frequency range from 20 Hz to 2 kHz. The minimum detectable wavelength-shift of the sensor system is 1×10-3 pm/Hz1/2.

  13. Development of a Microelectrode Array Sensing System for Water Quality Monitoring

    OpenAIRE

    Gardner, Robert D

    2008-01-01

    This thesis reports the design and fabrication of a low-cost reliable microelectrode array sensing platform and its application toward water quality monitoring, including heavy metal ion detection. Individually addressable microelectrodes were designed in a planar array on a nonconductive glass substrate by a photolithography method. The size, shape, composition, and functionality of the microelectrodes were theoretically explored in order to maximize performance. The microelectrode array se...

  14. Radiation profile measurements for edge transport barrier discharges in Compact Helical System using AXUV photodiode arrays

    International Nuclear Information System (INIS)

    The formation of edge transport barrier (ETB) has recently been found in Compact Helical System (CHS) plasmas heated by co-injected neutral beam injection (NBI) with strong gas puffing. This regime is characterized by the appearance of the steep gradient of the electron density near the edge following the abrupt drop of hydrogen Balmer alpha (Hα) line intensity. In addition to single channel pyroelectric detector as a conventional bolometer, we have employed unfiltered absolute extreme ultraviolet (AXUV) photodiode arrays as a simple and low-cost diagnostic to investigate spatial and temporal variations of radiation emissivity in the ETB discharges. A compact mounting module for a 20 channel AXUV photodiode array including an in-vacuum preamplifier for immediate current-voltage conversion has successfully been designed and fabricated. Two identical modules installed in the upper and lower viewports provide 40 lines of sight covering the inboard and outboard sides within the horizontally elongated cross section of the CHS plasma with wide viewing angle. Although spectral uniformity of the detector sensitivity of the AXUV photodiode is unsatisfied for photon energies lower than 200 eV, it has been confirmed that the signals of AXUV photodiode and pyroelectric detector in the ETB discharges show roughly the same behavior except for the very beginning and end of the discharges. The results of the measurements in typical ETB discharges show that the signals of all the channels of the AXUV photodiode arrays begin to increase more rapidly at the moment of the transition than before. The rate of the increase is larger for the edge viewing chords than for the center viewing ones, which indicates the flattening of the radiation profile following the change in the electron density profile after the formation of the ETB. However, the signals for the edge chords tend to saturate after several tens of milliseconds, while they still continue to increase for the central chords

  15. Preliminary results from a novel CdZnTe linear pad detector array x-ray imaging system

    International Nuclear Information System (INIS)

    The excellent energy-resolution and short charge collection time, especially the possibility of room temperature operation, make CdZnTe semiconductor detectors an excellent candidate for x-ray imaging and spectroscopic application in nuclear physics. Because of these characteristics, CdZnTe pad detectors with a novel geometry and approximately 1 mm2 pad area have been developed. These pad type linear arrays are new and important for many scanning type applications using a wide energy range from about 10 to 300 keV energies. A prototype x-ray imaging system has been developed consisting of a state-of-the-art pad type linear array of CdZnTe detectors manufactured by eV Products and low noise readout electronics developed by NOVA R and D, Inc. A series of measurements on the temperature dependence of the performance of CdZnTe linear pad detector arrays has been performed at NOVA R and D, Inc. The changes in dark (leakage) current against temperature have been studied. High resolution x-ray spectra has been obtained using 57Co source at different temperatures. A low noise front-end electronics ASIC chip for reading out the detector array was developed that can achieve fast data acquisition with dual energy imaging capability. Several prototype CdZnTe pad detector arrays are placed next to each other to form an approximately 30 cm long linear array. This array is used to make preliminary dual energy scanned images of complex objects using a 90 kV x-ray generator. Some of the images will be presented. The results show that the system is excellent for applications in industrial and medical imaging

  16. Numerical study of point spread function of a fast neutron radiography system based on scintillating-fiber array

    Institute of Scientific and Technical Information of China (English)

    ZHANG; FaQiang

    2007-01-01

    For a scintillating-fiber array fast-neutron radiography system, a point-spread- function computing model was introduced, and the simulation code was developed. The results of calculation show that fast-neutron radiographs vary with the size of fast neutron sources, the size of fiber cross-section and the imaging geometry. The results suggest that the following qualifications are helpful for a good point spread function: The cross-section of scintillating fibers not greater than 200μm×200μm, the size of neutron source as small as a few millimeters, the distance between the source and the scintillating fiber array greater than 1 m, and inspected samples placed as close as possible to the array. The results give suggestions not only to experiment considerations but also to the estimation of spatial resolution for a specific system.……

  17. Numerical study of point spread function of a fast neutron radiography system based on scintillating-fiber array

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ For a scintillating-fiber array fast-neutron radiography system, a point-spread- function computing model was introduced, and the simulation code was developed. The results of calculation show that fast-neutron radiographs vary with the size of fast neutron sources, the size of fiber cross-section and the imaging geometry. The results suggest that the following qualifications are helpful for a good point spread function: The cross-section of scintillating fibers not greater than 200μm×200μm, the size of neutron source as small as a few millimeters, the distance between the source and the scintillating fiber array greater than 1 m, and inspected samples placed as close as possible to the array. The results give suggestions not only to experiment considerations but also to the estimation of spatial resolution for a specific system.

  18. Detection of Crab Giant Pulses Using the Mileura Widefield Array Low Frequency Demonstrator Field Prototype System

    CERN Document Server

    Bhat, N D Ramesh; Knight, Haydon S; Bowman, Judd D; Oberoi, Divya; Barnes, David G; Briggs, Frank H; Cappallo, Roger J; Herne, David; Kocz, Jonathon; Lonsdale, Colin J; Lynch, Mervyn J; Stansby, Bruce; Stevens, Jamie; Torr, Glen; Webster, Rachel L; Wyithe, J Stuart B

    2007-01-01

    We report on the detection of giant pulses from the Crab Nebula pulsar at a frequency of 200 MHz using the field deployment system designed for the Mileura Widefield Array's Low Frequency Demonstrator (MWA-LFD). Our observations are among the first high-quality detections at such low frequencies. The measured pulse shapes are deconvolved for interstellar pulse broadening, yielding a pulse-broadening time of 670$\\pm$100 $\\mu$s, and the implied strength of scattering (scattering measure) is the lowest that is estimated towards the Crab nebula from observations made so far. The sensitivity of the system is largely dictated by the sky background, and our simple equipment is capable of detecting pulses that are brighter than $\\sim$9 kJy in amplitude. The brightest giant pulse detected in our data has a peak amplitude of $\\sim$50 kJy, and the implied brightness temperature is $10^{31.6}$ K. We discuss the giant pulse detection prospects with the full MWA-LFD system. With a sensitivity over two orders of magnitude l...

  19. A novel sub-camera array model for calibrating multi-mirror catadioptric systems

    International Nuclear Information System (INIS)

    The omni-directional catadioptric camera composed of multiple mirrors is a powerful tool that can acquire multiple wide field-of-view images and reconstruct the scene in a single shot. However, the non-central nature of the system poses significant challenges to the task of calibration. A novel off-center spherical projection (OCSP)-based sub-camera array model is proposed in this paper to address this problem. By inducing a movable spherical projection center in the traditional unified model, the OCSP sub-camera can efficiently deal with large misalignments that exist in multi-mirror systems. An efficient calibration method and the initialization algorithm are also presented. With the new model, calibration can be completed conveniently without the aid of a priori information on the mirrors and camera. The model is also compatible with traditional multi-view geometry, making 3D reconstruction straightforward for non-central systems. Experiments based on synthetic and real data on various types of mirrors show promising calibration results and thus verify the effectiveness of the method. (paper)

  20. Simultaneous multi-element atomic absorption system using photodiode array detector

    International Nuclear Information System (INIS)

    A photodiode array (PDA) detector-multichannel analyser (MCA) system has been coupled to a flame and a graphite furnace atomiser and tested for simultaneous multielement atomic absorption analysis. Multielement hollow cathode lamps (HCL) are used as light source. Spectral lines are dispersed through a spectrograph with triple gratings and detected by a 25.4 mm PDA detector consisting of 1024 elements. The optical MCA system is capable of recording multiple spectra spanned by the spectrograph/PDA. The transmitted intensity spectra obtained for the standard and analyte solutions during flame or graphite furnace atomisation are converted to absorbance spectra using the MCA software provided. Results from the comparison studies show that the linear range and sensitivities for Ni-Co-Fe and Cu-Cr obtained from the simultaneous measurements are within the same order of magnitudes as those from conventional single element determinations using photomultiplier tube detection. The study also shows that non-atomic absorption can be readily corrected by a two-line method where non-atomic absorption lines can be chosen from the spectra recorded simultaneously. The proposed system has been evaluated for the determination of trace elements using NBS standard reference water SRM 1643b

  1. Very low noise AC/DC power supply systems for large detector arrays

    Science.gov (United States)

    Arnaboldi, C.; Baù, A.; Carniti, P.; Cassina, L.; Giachero, A.; Gotti, C.; Maino, M.; Passerini, A.; Pessina, G.

    2015-12-01

    In this work, we present the first part of the power supply system for the CUORE and LUCIFER arrays of bolometric detectors. For CUORE, it consists of AC/DC commercial power supplies (0-60 V output) followed by custom DC/DC modules (48 V input, ±5 V to ±13.5 V outputs). Each module has 3 floating and independently configurable output voltages. In LUCIFER, the AC/DC + DC/DC stages are combined into a commercial medium-power AC/DC source. At the outputs of both setups, we introduced filters with the aim of lowering the noise and to protect the following stages from high voltage spikes that can be generated by the energy stored in the cables after the release of accidental short circuits. Output noise is very low, as required: in the 100 MHz bandwidth the RMS level is about 37 μVRMS (CUORE setup) and 90 μVRMS (LUCIFER setup) at a load of 7 A, with a negligible dependence on the load current. Even more importantly, high frequency switching disturbances are almost completely suppressed. The efficiency of both systems is above 85%. Both systems are completely programmable and monitored via CAN bus (optically coupled).

  2. JOINT SPACE-FREQUENCY MULTIUSER SYMBOL DETECTOR FOR MC-CDMA SYSTEM WITH UNIFORM LINEAR ARRAY

    Institute of Scientific and Technical Information of China (English)

    Wu Xiaojun; Yin Qinye; Feng Aigang; Zhao Zheng; Zhang Jianguo

    2002-01-01

    The MultiCarrier Code Division Multiple Access (MC-CDMA) scheme is promising for relieving capacity limit problems of Direct Sequence (DS-) CDMA systems due to serious InterChip Interference (ICI) and MultiUser Interference (MUI) in high-data-rate wireless communication systems. In this paper, the Uniform Linear Array (ULA) is applied to the base station of macrocellular MC-CDMA systems in a frequency-selective fading channel environment. A joint space-frequency multiuser symbol sequence detector is developed for all active users within one macrocell without space-frequency channel estimation. Simultaneously, Directions-Of-Arrivals (DOAs) of all active users can also be estimated. By dividing the ULA into two identical overlapping subarrays, a specific auxiliary matrix is constructed, which includes both symbol sequence and DOA information of all active users. Then, based on the subspace method, performing the eigen decomposition on such auxiliary matrix, the closed-form solution of symbol sequences and DOAs for all active users can be obtained. In comparison with schemes based on channel estimation, our algorithm need not explicitly estimate the space-frequency channel for each active user,so it has lower computation complexity. Extensive computer simulations demonstrate the overall performance of this novel scheme.

  3. JOINT SPACE-FREQUENCY MULTIUSER SYMBOL DETECTOR FOR MC-CDMA SYSTEM WITH UNIFORM LINEAR ARRAY

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The MultiCarrier COde Division Multiple Access (MC-CDMA) scheme is promising for relieving capacity limit problems of Direct Sequence(DS-CDMA systems due to serious InterCip Interference(ICI) and MultiUser Interference(MUI)in high-data-rate wireless communication systems.In this paper the Uniform Linear Array(ULA) is applied to the base station of macrocellular MC-CDMA systems in a frequency-selective fading channel environment.A joint space-frequency multiuser symblo sequence detector is developed for all active users within one macrocell without space-frequency channel estimation.Simultaneously,Directions-of -Arrivals (ODAs)of all active users can also be estimated.By dividing the ULA into two identical overlapping subarrays,a specific auxiliary matrix is constructed,which includes both symbol sequence and DOA information of all active users,Then,based on the subspace method,performing the eigen decomposition on such auxiliary matrix,the closed-form solution of symbol sequences and DOAs for all active users can be obtained.In comparison with schemes based on channel estimation,our algorithm need not explicitly estimate the space-frequency channel for each active user,so it has lower computation complexity,Extensive computer simulations demonstrate the overall performance of this novel scheme.

  4. Array-based DNA methylation profiling of primary lymphomas of the central nervous system

    International Nuclear Information System (INIS)

    Although primary lymphomas of the central nervous system (PCNSL) and extracerebral diffuse large B-cell lymphoma (DLBCL) cannot be distinguished histologically, it is still a matter of debate whether PCNSL differ from systemic DLBCL with respect to their molecular features and pathogenesis. Analysis of the DNA methylation pattern might provide further data distinguishing these entities at a molecular level. Using an array-based technology we have assessed the DNA methylation status of 1,505 individual CpG loci in five PCNSL and compared the results to DNA methylation profiles of 49 DLBCL and ten hematopoietic controls. We identified 194 genes differentially methylated between PCNSL and normal controls. Interestingly, Polycomb target genes and genes with promoters showing a high CpG content were significantly enriched in the group of genes hypermethylated in PCNSL. However, PCNSL and systemic DLBCL did not differ in their methylation pattern. Based on the data presented here, PCNSL and DLBCL do not differ in their DNA methylation pattern. Thus, DNA methylation analysis does not support a separation of PCNSL and DLBCL into individual entities. However, PCNSL and DLBCL differ in their DNA methylation pattern from non- malignant controls

  5. The Design of FPGA-based Array CCD Sensor Drive System

    Directory of Open Access Journals (Sweden)

    Chengtao Cai

    2014-01-01

    Full Text Available CCD Sensor is the crutial equipment for environment perception which is widely used in various fields such as surveilliance,vision navigation and machine vision. The commercial CCD device has been encapsulated the sensor driver inside which is not opened for secondary development. Even this mode facilitate the usage but it really can not content the customizable need. For solving this challenging but imperative issue, we designed a novel CCD sensor driver system which implement the efficient and effective image acquisition task in customizing approach. The working principle and driving timing sequence about ICX625AQA the interline CCD image sensor used in our system are discussed in detail. For handling with this data intensive task, a high performance Field Programmable GateArray (FPGA controller is used for data allocation and translation, the peripheral circuits including AD9974 and CXD3400 drive interface which process the horizontal signal and vertical signal, respectively. The designed system proposed at the end of this paper.

  6. Performance study of an OFDM visible light communication system based on white LED array

    Science.gov (United States)

    Tian, Chong-Wen; Li, Yan-Ting; Ye, Wei-Lin; Quan, Xiang-Yin; Song, Zhanwei; Zheng, Chuan-Tao

    2011-11-01

    By introducing orthogonal frequency division multiplexing (OFDM) technology, a visible light communication (VLC) system using a 5×5 white LED array is studied in this paper. The OFDM transmitter and receiver are modeled through MATLAB/Simulink tool. The electrical-optical-electrical (EOE) response of the VLC channel, which is also the response of the detector, is derived based on Lambert's lighting model. Then the modeling on the overall OFDM/VLC system is established by combining the above three models together. The effects of the factors which include the digital modulation, Reed-Solomon (RS) coding, pilot form, pilot ratio (PR) and communication distance on the bit error rate (BER) of the system are discussed. The results show that through the use of RS coding, block pilot, quadrate phase shift keying (QPSK) modulation and a suitable pilot ratio about 1/3, under the communication rate about 550 kbit/s, the BER can be dropped to below 10-5, and the communication distance can reach 0.9 m.

  7. On the control and prediction of the heating patterns of the annular phased array hyperthermia system

    International Nuclear Information System (INIS)

    In previous publications the authors examined the electromagnetic (EM) power deposition and heating of the Annular Phased Array (APA) system developed by BSD Medical Corporation, using numerical EM and thermodynamics modeling. In this paper the results of recent efforts to vary and control the heating patterns produced by this system are described. in particular, data from several numerical simulations and experimental measurements are presented which illustrate the effect on the heating patterns achieved by varying the phase difference between the different ports of the APA system. Other heating patterns, produced by inactivating some of the APA ports, are also discussed. The remainder of the paper focuses on the feasibility of predicting the EM power depositions patterns of the APA solely through monitoring the E-field in the water bolus around the patient's body. In particular, it is shown that this E-field distribution depends primarily upon the outer geometry of the human body and is largely insensitive to the detailed distribution of inner tissues. Specific suggestions regarding the types, number, and location of E-field probes that can be used for such measurements are also given

  8. Performance Enhancement of Underwater Target Tracking by Fusing Data of Array of Global Positioning System Sonobuoys

    Directory of Open Access Journals (Sweden)

    Ahmed El-Shafie

    2009-01-01

    Full Text Available Problem statement: An accurate knowledge of geographic positions of sonobuoys is critical for the conduct of antisubmarine warfare operations and detected target localization. Deployed from an airborne platform or a surface vessel, arrays of sonobuoys could be used to efficiently track and localize submarines. Lastly, some sonobuoys were being equipped with GPS for improving system accuracy and potentially allowing networked Sonobuoy positioning. However, the computation of the range using the propagation loss profile and the data of one sonobuoy usually leads to inaccurate target localization due to several effects and uncertainties. It was, alternatively, reported that if the target is within the detection rage of two or more sonobuoys, greatly improved target localization can be achieved. Approach: Aim of this research was to investigate the feasibility of fusing data from a distributed field of GPS sonobuoys to create an Artificial Intelligence (AI based model for the error of the range computation in case of the target being detected by only one sonobuoy. Proposed module was designed utilizing Adaptive Neuron-Fuzzy Inference Systems (ANFIS to estimate the range error associated with the computation using the propagation loss profile when the target is within the detection range of only one sonobuoy. The architecture of the proposed ANFIS system had two unique features. First was the real-time cross-validation applied during the update (training procedure of the ANFIS-based module while the target was detected by two sonobuoys and the range was computed. Second feature was the use of non-overlapping and moving window for the real-time implementation of the ANFIS-based data fusion module. Results: Performance of the proposed system was examined with simulation data considering different scenarios for both the array of GPS sonobuoys and the target. Results showed that the corrected positioning by one sonobuoy is completely following the

  9. A Customized Metal Oxide Semiconductor-Based Gas Sensor Array for Onion Quality Evaluation: System Development and Characterization

    Directory of Open Access Journals (Sweden)

    Tharun Konduru

    2015-01-01

    Full Text Available A gas sensor array, consisting of seven Metal Oxide Semiconductor (MOS sensors that are sensitive to a wide range of organic volatile compounds was developed to detect rotten onions during storage. These MOS sensors were enclosed in a specially designed Teflon chamber equipped with a gas delivery system to pump volatiles from the onion samples into the chamber. The electronic circuit mainly comprised a microcontroller, non-volatile memory chip, and trickle-charge real time clock chip, serial communication chip, and parallel LCD panel. User preferences are communicated with the on-board microcontroller through a graphical user interface developed using LabVIEW. The developed gas sensor array was characterized and the discrimination potential was tested by exposing it to three different concentrations of acetone (ketone, acetonitrile (nitrile, ethyl acetate (ester, and ethanol (alcohol. The gas sensor array could differentiate the four chemicals of same concentrations and different concentrations within the chemical with significant difference. Experiment results also showed that the system was able to discriminate two concentrations (196 and 1964 ppm of methlypropyl sulfide and two concentrations (145 and 1452 ppm of 2-nonanone, two key volatile compounds emitted by rotten onions. As a proof of concept, the gas sensor array was able to achieve 89% correct classification of sour skin infected onions. The customized low-cost gas sensor array could be a useful tool to detect onion postharvest diseases in storage.

  10. Statistical analysis of storm electrical discharges reconstituted from a lightning mapping system, a lightning location system, and an acoustic array

    Science.gov (United States)

    Gallin, Louis-Jonardan; Farges, Thomas; Marchiano, Régis; Coulouvrat, François; Defer, Eric; Rison, William; Schulz, Wolfgang; Nuret, Mathieu

    2016-04-01

    In the framework of the European Hydrological Cycle in the Mediterranean Experiment project, a field campaign devoted to the study of electrical activity during storms took place in the south of France in 2012. An acoustic station composed of four microphones and four microbarometers was deployed within the coverage of a Lightning Mapping Array network. On the 26 October 2012, a thunderstorm passed just over the acoustic station. Fifty-six natural thunder events, due to cloud-to-ground and intracloud flashes, were recorded. This paper studies the acoustic reconstruction, in the low frequency range from 1 to 40 Hz, of the recorded flashes and their comparison with detections from electromagnetic networks. Concurrent detections from the European Cooperation for Lightning Detection lightning location system were also used. Some case studies show clearly that acoustic signal from thunder comes from the return stroke but also from the horizontal discharges which occur inside the clouds. The huge amount of observation data leads to a statistical analysis of lightning discharges acoustically recorded. Especially, the distributions of altitudes of reconstructed acoustic detections are explored in detail. The impact of the distance to the source on these distributions is established. The capacity of the acoustic method to describe precisely the lower part of nearby cloud-to-ground discharges, where the Lightning Mapping Array network is not effective, is also highlighted.

  11. Systems impact of a concentrated solar array on a Jupiter orbiter

    Energy Technology Data Exchange (ETDEWEB)

    Rockey, D.E.; Bamford, R.; Hollars, M.G.; Klemetson, R.W.; Koerner, T.W.; Marsh, E.L.; Price, H.; Uphoff, C.

    1981-01-01

    Study results in this paper indicate that a Galileo Jupiter orbiting mission could be performed with a concentrated solar array power source. A baseline spacecraft design using concentrated arrays is presented and the overall spacecraft implications for attitude control, propulsion, power conditioning and the resultant spacecraft mass are examined. 4 refs.

  12. System and method for generating a deselect mapping for a focal plane array

    Science.gov (United States)

    Bixler, Jay V; Brandt, Timothy G; Conger, James L; Lawson, Janice K

    2013-05-21

    A method for generating a deselect mapping for a focal plane array according to one embodiment includes gathering a data set for a focal plane array when exposed to light or radiation from a first known target; analyzing the data set for determining which pixels or subpixels of the focal plane array to add to a deselect mapping; adding the pixels or subpixels to the deselect mapping based on the analysis; and storing the deselect mapping. A method for gathering data using a focal plane array according to another embodiment includes deselecting pixels or subpixels based on a deselect mapping; gathering a data set using pixels or subpixels in a focal plane array that are not deselected upon exposure thereof to light or radiation from a target of interest; and outputting the data set.

  13. SU-E-T-111: Development of Proton Dosimetry System Using Fiber-Optic Cerenkov Radiation Sensor Array

    International Nuclear Information System (INIS)

    Purpose: We had developed and evaluated a new dosimetric system for proton therapy using array of fiber-optic Cerenkov radiation sensor (FOCRS) which can measure a percent depth dose (PDD) instantly. In this study, the Bragg peaks and spread out Bragg peak (SOBP) of the proton beams measured by FOCRS array were compared with those measured by an ion chamber. Methods and Method: We fabricated an optical fiber array of FOCRS in a handmade phantom which is composed of poly-methyl methacrylate (PMMA). There are 75 holes of 1mm diameter inside the phantom which is designed to be exposed in direction of beam when it is emerged in water phantom. The proton beam irradiation was carried out using IBA cyclotron PROTEUS 235 at national cancer center in Korea and a commercial data acquisition system was used to digitize the analog signal. Results: The measured Bragg peak and SOBP for the proton ranges of 7∼ 20 cm were well matched with the result from ion chamber. The comparison results show that the depth of proton beam ranges and the width of SOBP measured by array of FOCRS are comparable with the measurement from multi-layer ion chamber (MLIC) although there are some uncertainty in the measurement of FOCRS array for some specific beam ranges. Conclusion: The newly developed FOCRS array based dosimetric system for proton therapy can efficiently reduce the time and effort needed for proton beam range measurement compared to the conventional method and has the potential to be used for the proton pencil beam application

  14. SU-E-T-111: Development of Proton Dosimetry System Using Fiber-Optic Cerenkov Radiation Sensor Array

    Energy Technology Data Exchange (ETDEWEB)

    Son, J [National Cancer Center, Ilsan, Gyeonggi-do, Korea University, Seoul (Korea, Republic of); Kim, M; Shin, D; Lim, Y; Lee, S; Kim, J; Kim, J [National Cancer Center, Goyangsi, Gyeonggi-do (Korea, Republic of); Hwang, U [National Medical Center in Korea, Seoul, Seoul (Korea, Republic of); Yoon, M [Korea University, Seoul (Korea, Republic of)

    2014-06-01

    Purpose: We had developed and evaluated a new dosimetric system for proton therapy using array of fiber-optic Cerenkov radiation sensor (FOCRS) which can measure a percent depth dose (PDD) instantly. In this study, the Bragg peaks and spread out Bragg peak (SOBP) of the proton beams measured by FOCRS array were compared with those measured by an ion chamber. Methods and Method: We fabricated an optical fiber array of FOCRS in a handmade phantom which is composed of poly-methyl methacrylate (PMMA). There are 75 holes of 1mm diameter inside the phantom which is designed to be exposed in direction of beam when it is emerged in water phantom. The proton beam irradiation was carried out using IBA cyclotron PROTEUS 235 at national cancer center in Korea and a commercial data acquisition system was used to digitize the analog signal. Results: The measured Bragg peak and SOBP for the proton ranges of 7∼ 20 cm were well matched with the result from ion chamber. The comparison results show that the depth of proton beam ranges and the width of SOBP measured by array of FOCRS are comparable with the measurement from multi-layer ion chamber (MLIC) although there are some uncertainty in the measurement of FOCRS array for some specific beam ranges. Conclusion: The newly developed FOCRS array based dosimetric system for proton therapy can efficiently reduce the time and effort needed for proton beam range measurement compared to the conventional method and has the potential to be used for the proton pencil beam application.

  15. A preliminary evaluation work on a 3D ultrasound imaging system for 2D array transducer

    Science.gov (United States)

    Zhong, Xiaoli; Li, Xu; Yang, Jiali; Li, Chunyu; Song, Junjie; Ding, Mingyue; Yuchi, Ming

    2016-04-01

    This paper presents a preliminary evaluation work on a pre-designed 3-D ultrasound imaging system. The system mainly consists of four parts, a 7.5MHz, 24×24 2-D array transducer, the transmit/receive circuit, power supply, data acquisition and real-time imaging module. The row-column addressing scheme is adopted for the transducer fabrication, which greatly reduces the number of active channels . The element area of the transducer is 4.6mm by 4.6mm. Four kinds of tests were carried out to evaluate the imaging performance, including the penetration depth range, axial and lateral resolution, positioning accuracy and 3-D imaging frame rate. Several strong reflection metal objects , fixed in a water tank, were selected for the purpose of imaging due to a low signal-to-noise ratio of the transducer. The distance between the transducer and the tested objects , the thickness of aluminum, and the seam width of the aluminum sheet were measured by a calibrated micrometer to evaluate the penetration depth, the axial and lateral resolution, respectively. The experiment al results showed that the imaging penetration depth range was from 1.0cm to 6.2cm, the axial and lateral resolution were 0.32mm and 1.37mm respectively, the imaging speed was up to 27 frames per second and the positioning accuracy was 9.2%.

  16. In vivo imaging of inducible tyrosinase gene expression with an ultrasound array-based photoacoustic system

    Science.gov (United States)

    Harrison, Tyler; Paproski, Robert J.; Zemp, Roger J.

    2012-02-01

    Tyrosinase, a key enzyme in the production of melanin, has shown promise as a reporter of genetic activity. While green fluorescent protein has been used extensively in this capacity, it is limited in its ability to provide information deep in tissue at a reasonable resolution. As melanin is a strong absorber of light, it is possible to image gene expression using tyrosinase with photoacoustic imaging technologies, resulting in excellent resolutions at multiple-centimeter depths. While our previous work has focused on creating and imaging MCF-7 cells with doxycycline-controlled tyrosinase expression, we have now established the viability of these cells in a murine model. Using an array-based photoacoustic imaging system with 5 MHz center frequency, we capture interleaved ultrasound and photoacoustic images of tyrosinase-expressing MCF-7 tumors both in a tissue mimicking phantom, and in vivo. Images of both the tyrosinase-expressing tumor and a control tumor are presented as both coregistered ultrasound-photoacoustic B-scan images and 3-dimensional photoacoustic volumes created by mechanically scanning the transducer. We find that the tyrosinase-expressing tumor is visible with a signal level 12dB greater than that of the control tumor in vivo. Phantom studies with excised tumors show that the tyrosinase-expressing tumor is visible at depths in excess of 2cm, and have suggested that our imaging system is sensitive to a transfection rate of less than 1%.

  17. Performance optimization of dense-array concentrator photovoltaic system considering effects of circumsolar radiation and slope error.

    Science.gov (United States)

    Wong, Chee-Woon; Chong, Kok-Keong; Tan, Ming-Hui

    2015-07-27

    This paper presents an approach to optimize the electrical performance of dense-array concentrator photovoltaic system comprised of non-imaging dish concentrator by considering the circumsolar radiation and slope error effects. Based on the simulated flux distribution, a systematic methodology to optimize the layout configuration of solar cells interconnection circuit in dense array concentrator photovoltaic module has been proposed by minimizing the current mismatch caused by non-uniformity of concentrated sunlight. An optimized layout of interconnection solar cells circuit with minimum electrical power loss of 6.5% can be achieved by minimizing the effects of both circumsolar radiation and slope error. PMID:26367685

  18. On the recognition of compromise in sensing systems: rewired acoustic arrays and distorted route estimation and classification

    Science.gov (United States)

    Thornley, David J.; Damarla, Thyagaraju; Srivastava, Mani B.; Mylaraswami, Dinkar

    2009-09-01

    A group of acoustic arrays that provide direction of approach estimates also support classification of vehicles using the beams formed during that estimation. Successful simultaneous tracking and classification has demonstrated the value of such a sensing resource as a UGS installation. We now consider potential attacks on the integrity of such an installation, describing the effect of compromised acoustic arrays in the data analysis and tracking and classification results. We indicate how these can be automatically recognized, and note that calibration methods intended for deployment time can be used for recovery during operation, which opens the door to methods for recovery from the compromise without re-configuring the equipment, using abductive reasoning to discover the necessary re-processing structure. By rotating an acoustic array, the tracking stability and implied path of a tracked entity can be distorted while leaving the data and analysis from individual arrays self-consistent. Less structured modifications, such as unstructured re-ordering of microphone connections, impact the basic data analysis. We examine the effect of these classes of attack on the integrity of a set of unattended acoustic arrays, and consider the steps necessary for detection, diagnosis, and recovering an effective sensing system. Understaning these steps plays an important part in reasoning in support of balance of investment, planning, operation and post-hoc analysis.

  19. Low Cost Em Signal Spectral Analysis with Two Element Time Modulated Array System by Multiple Signal Classification Algorithms

    Directory of Open Access Journals (Sweden)

    G. Balagurappa,

    2014-03-01

    Full Text Available Today homeland security is a big matter of concern. The present day wireless technology is available to anti-social elements, who are using this in several undesirable manners. By knowing the direction of the source of electromagnetic waves it becomes possible to locate such anti-social groups and take offensive action. In military applications also finding the direction of the signal source becomes very valuable information. The direction finding systems can achieve this goal. Conventional radio direction finding (RDF systems often use an array of two or more antennas and use either phase-comparison or amplitude-comparison of the received signals to determine direction of arrival information. In both of these techniques directional information is derived by processing array data at the receive signal frequency. In this project an alternative approach to direction finding using the concept of a time-switched array is proposed. The time-switched array system uses simple signal processing techniques to provide a directional main beam and pattern nulls at harmonic frequencies. To determine two dimensional angles is three elements, the system cost has been mostly minimised. we now consider the problem of using our low cost system to detect and estimate the direction of arrival of a desired signal in the presence of array antenna. The proposed scheme is cost effective technique in comparison with the existing schemes. MATLAB/GNU OCTAVE simulation tool will be used for simulation. The simulation results, applications, merits and demerits of proposed approach will be analyzed and will be documented.

  20. Electrophoresis-mass spectrometry probe

    Science.gov (United States)

    Andresen, Brian D.; Fought, Eric R.

    1987-01-01

    The invention involves a new technique for the separation of complex mixtures of chemicals, which utilizes a unique interface probe for conventional mass spectrometers which allows the electrophoretically separated compounds to be analyzed in real-time by a mass spectrometer. This new chemical analysis interface, which couples electrophoresis with mass spectrometry, allows complex mixtures to be analyzed very rapidly, with much greater specificity, and with greater sensitivity. The interface or probe provides a means whereby large and/or polar molecules in complex mixtures to be completely characterized. The preferred embodiment of the probe utilizes a double capillary tip which allows the probe tip to be continually wetted by the buffer, which provides for increased heat dissipation, and results in a continually operating interface which is more durable and electronically stable than the illustrated single capillary tip probe interface.

  1. Analytical biotechnology: Capillary electrophoresis and chromatography

    International Nuclear Information System (INIS)

    The papers describe the separation, characterization, and equipment required for the electrophoresis or chromatography of cyclic nucleotides, pharmaceuticals, therapeutic proteins, recombinant DNA products, pheromones, peptides, and other biological materials. One paper, On-column radioisotope detection for capillary electrophoresis, has been indexed separately for inclusion on the data base

  2. Signal-Conditioning Block of a 1 × 200 CMOS Detector Array for a Terahertz Real-Time Imaging System

    Directory of Open Access Journals (Sweden)

    Jong-Ryul Yang

    2016-03-01

    Full Text Available A signal conditioning block of a 1 × 200 Complementary Metal-Oxide-Semiconductor (CMOS detector array is proposed to be employed with a real-time 0.2 THz imaging system for inspecting large areas. The plasmonic CMOS detector array whose pixel size including an integrated antenna is comparable to the wavelength of the THz wave for the imaging system, inevitably carries wide pixel-to-pixel variation. To make the variant outputs from the array uniform, the proposed signal conditioning block calibrates the responsivity of each pixel by controlling the gate bias of each detector and the voltage gain of the lock-in amplifiers in the block. The gate bias of each detector is modulated to 1 MHz to improve the signal-to-noise ratio of the imaging system via the electrical modulation by the conditioning block. In addition, direct current (DC offsets of the detectors in the array are cancelled by initializing the output voltage level from the block. Real-time imaging using the proposed signal conditioning block is demonstrated by obtaining images at the rate of 19.2 frame-per-sec of an object moving on the conveyor belt with a scan width of 20 cm and a scan speed of 25 cm/s.

  3. Signal-Conditioning Block of a 1 × 200 CMOS Detector Array for a Terahertz Real-Time Imaging System.

    Science.gov (United States)

    Yang, Jong-Ryul; Lee, Woo-Jae; Han, Seong-Tae

    2016-01-01

    A signal conditioning block of a 1 × 200 Complementary Metal-Oxide-Semiconductor (CMOS) detector array is proposed to be employed with a real-time 0.2 THz imaging system for inspecting large areas. The plasmonic CMOS detector array whose pixel size including an integrated antenna is comparable to the wavelength of the THz wave for the imaging system, inevitably carries wide pixel-to-pixel variation. To make the variant outputs from the array uniform, the proposed signal conditioning block calibrates the responsivity of each pixel by controlling the gate bias of each detector and the voltage gain of the lock-in amplifiers in the block. The gate bias of each detector is modulated to 1 MHz to improve the signal-to-noise ratio of the imaging system via the electrical modulation by the conditioning block. In addition, direct current (DC) offsets of the detectors in the array are cancelled by initializing the output voltage level from the block. Real-time imaging using the proposed signal conditioning block is demonstrated by obtaining images at the rate of 19.2 frame-per-sec of an object moving on the conveyor belt with a scan width of 20 cm and a scan speed of 25 cm/s. PMID:26950128

  4. Research on pre-staining gel electrophoresis

    International Nuclear Information System (INIS)

    Background: Gel electrophoresis is a powerful biochemical separation technique. Most biological molecules are completely transparent in the visible region of light, so it is necessary to use staining to show the results after gel electrophoresis, and the general steps of conventional staining methods are time-consuming. Purpose: We try to develop a novel approach to simplify the gel electrophoresis: Pre-Staining Gel Electrophoresis (PSGE), which can make the gel electrophoresis results monitored in real time. Methods: Pre-stain the protein samples with Coomassie Brilliant Blue (CBB) for 30 min before loading the sample into the gel well. Results and Conclusion: PSGE can be successfully used to analyze the binding efficiency of Bovine Serum Albumin (BSA) and amphiphilic polymer via chemical coupling and physical absorption, and the double PSGE also shows a great potential in bio-analytical chemistry. (authors)

  5. A 32x32 pixel focal plane array ladar system using chirped amplitude modulation

    Science.gov (United States)

    Stann, Barry L.; Aliberti, Keith; Carothers, Daniel; Dammann, John; Dang, Gerard; Giza, Mark M.; Lawler, William B.; Redman, Brian C.; Simon, Deborah R.

    2004-09-01

    The Army Research Laboratory is researching system architectures and components required to build a 32x32 pixel scannerless ladar breadboard. The 32x32 pixel architecture achieves ranging based on a frequency modulation/continuous wave (FM/cw) technique implemented by directly amplitude modulating a near-IR diode laser transmitter with a radio frequency (RF) subcarrier that is linearly frequency modulated (i.e. chirped amplitude modulation). The backscattered light is focused onto an array of metal-semiconductor-metal (MSM) detectors where it is detected and mixed with a delayed replica of the laser modulation signal that modulates the responsivity of each detector. The output of each detector is an intermediate frequency (IF) signal (a product of the mixing process) whose frequency is proportional to the target range. Pixel read-out is achieved using code division multiple access techniques as opposed to the usual time-multiplexed techniques to attain high effective frame rates. The raw data is captured with analog-to-digital converters and fed into a PC to demux the pixel data, compute the target ranges, and display the imagery. Last year we demonstrated system proof-of-principle for the first time and displayed an image of a scene collected in the lab that was somewhat corrupted by pixel-to-pixel cross-talk. This year we report on system modifications that reduced pixel-to-pixel cross-talk and new hardware and display codes that enable near real-time stereo display of imagery on the ladar's control computer. The results of imaging tests in the laboratory will also be presented.

  6. Development of Frequency-Division Multiplexing Readout System for Large-Format TES X-ray Microcalorimeter Arrays

    Science.gov (United States)

    Sakai, K.; Yamamoto, R.; Takei, Y.; Mitsuda, K.; Yamasaki, N. Y.; Hidaka, M.; Nagasawa, S.; Kohjiro, S.; Miyazaki, T.

    2016-07-01

    We are developing the frequency-division multiplexing (FDM) readout system aimed to realize the 400-pixel transition edge sensor (TES) microcalorimeter array for the DIOS mission as well as large-format arrays with more than a thousand of TES for future space missions such as the ATHENA mission. The developed system consists of the low-power superconducting quantum interference device (SQUID), the digital FDM electronics, and the analog front-end to bridge the SQUID and the digital electronics. Using the developed readout system, we performed a TES readout experiment and succeeded to multiplex four TES signals with the single-staged cryogenic setup. We have experienced two issues during the experiment: an excess noise and crosstalk. The brief overview of the developed system and the details, results, and issues of the TES multiplexing readout experiment is discussed.

  7. Development of Frequency-Division Multiplexing Readout System for Large-Format TES X-ray Microcalorimeter Arrays

    Science.gov (United States)

    Sakai, K.; Yamamoto, R.; Takei, Y.; Mitsuda, K.; Yamasaki, N. Y.; Hidaka, M.; Nagasawa, S.; Kohjiro, S.; Miyazaki, T.

    2016-03-01

    We are developing the frequency-division multiplexing (FDM) readout system aimed to realize the 400-pixel transition edge sensor (TES) microcalorimeter array for the DIOS mission as well as large-format arrays with more than a thousand of TES for future space missions such as the ATHENA mission. The developed system consists of the low-power superconducting quantum interference device (SQUID), the digital FDM electronics, and the analog front-end to bridge the SQUID and the digital electronics. Using the developed readout system, we performed a TES readout experiment and succeeded to multiplex four TES signals with the single-staged cryogenic setup. We have experienced two issues during the experiment: an excess noise and crosstalk. The brief overview of the developed system and the details, results, and issues of the TES multiplexing readout experiment is discussed.

  8. The Optical System for the Large Size Telescope of the Cherenkov Telescope Array

    CERN Document Server

    Hayashida, M; Teshima, M; de Almeida, U Barres; Chikawa, M; Cho, N; Fukami, S; Gadola, A; Hanabata, Y; Horns, D; Jablonski, C; Katagiri, H; Kagaya, M; Ogino, M; Okumura, A; Saito, T; Stadler, R; Steiner, S; Straumann, U; Vollhardt, A; Wetteskind, H; Yamamoto, T; Yoshida, T

    2015-01-01

    The Large Size Telescope (LST) of the Cherenkov Telescope Array (CTA) is designed to achieve a threshold energy of 20 GeV. The LST optics is composed of one parabolic primary mirror 23 m in diameter and 28 m focal length. The reflector dish is segmented in 198 hexagonal, 1.51 m flat to flat mirrors. The total effective reflective area, taking into account the shadow of the mechanical structure, is about 368 m$^2$. The mirrors have a sandwich structure consisting of a glass sheet of 2.7 mm thickness, aluminum honeycomb of 60 mm thickness, and another glass sheet on the rear, and have a total weight about 47 kg. The mirror surface is produced using a sputtering deposition technique to apply a 5-layer coating, and the mirrors reach a reflectivity of $\\sim$94% at peak. The mirror facets are actively aligned during operations by an active mirror control system, using actuators, CMOS cameras and a reference laser. Each mirror facet carries a CMOS camera, which measures the position of the light spot of the optical ...

  9. Simultaneous Detection of Different MicroRNA Types Using the ZIP-Code Array System

    Science.gov (United States)

    Weishaupt, Sonja U.; Rupp, Steffen

    2013-01-01

    MicroRNAs (miRNAs) are important negative regulators of gene expression. Their implication in tumorigenesis is based on their dysregulation in many human cancer diseases. Interestingly, in tumor cells, an altered ratio of precursor and mature miRNA levels has been described. Consequently, differences in miRNA type levels have a high potential as biomarkers and comparative high-throughput-based detection might permit a more accurate characterization of subtypes, especially in the case of very heterogeneous tumor entities. Several molecular methods exist for the detection of mature and precursor miRNAs. DNA microarrays are predestinated as a high-throughput method for comprehensive miRNA detection in tumors. However, the simultaneous array-based detection of both these miRNA types is limited because the mature miRNA sequence is identically present in both forms. Here we present a ZIP-code DNA microarray-based system in combination with a novel labeling approach, which enables the simultaneous detection of precursor and mature miRNAs in one single experiment. Using synthetic miRNA templates, we demonstrate the specificity of the method for the different miRNA types, as well as the detection range up to four orders of magnitude. Moreover, mature and precursor miRNAs were detected and validated in human tumor cells. PMID:24078866

  10. An advanced Ka band phased array communication system at commercial frequencies

    Science.gov (United States)

    Wald, Lawrence; Kacpura, Thomas; Kershner, Dennis

    2000-01-01

    The Glenn Research Center (GRC) Direct Data Distribution (D3) project will demonstrate an advanced, high-performance communication system that transmits information from a technology payload carried by the Space Shuttle in low-Earth orbit (LEO) to a small receiving terminal on the Earth. The Shuttle-based communications package will utilize a solid-state, Ka-band phased array antenna that electronically steers the 19.05 Ghz RF signal toward a low-cost, tracking ground terminal, thereby providing agile, vibration-free, electronic steering at reduced size and weight with increased reliability. The project will also demonstrate new digital modulation and processing technology that will allow transmission of user/platform data at rates up to 1200 Mbits per second. This capability will enable the management of the substantially increased amounts of data to be collected from the International Space Station (ISS) or other LEO platforms directly to NASA field centers, principal investigators, or into the commercial terrestrial communications network. .

  11. Feasibility of MatriXX 2D detector array for HDR brachytherapy planning system assessment

    International Nuclear Information System (INIS)

    IBA Dosimetry GmbH participated in the Joint Research Project 'Increasing cancer treatment efficacy using 3D brachytherapy' as a non-funded partner in the work package which was mostly dedicated to the determination of dose-to-water distribution from a high-dose-rate (HDR) brachytherapy source. The dose distribution was measured with a MatriXX (MXX) 2D detector array and compared with Dose Cube Data, calculated by treatment planning systems (TPS). All measurements and calculations were performed in cooperation with OUSA, Bratislava and FNB, Prague. The comparison has been carried out for three irradiation geometries: single source position, single line and four line motions of the source, and with the effective point of measurement in a plane at 6 mm, 10 mm and 20 mm distance from the source position. The comparison of the MXX measurements and the TPS calculations was evaluated by the commercial IBA Dosimetry software OmniPro I'mRT (1) as the difference between maximum of measured and calculated values and (2) as the maximum difference between the two-dimensional distributions of measured and calculated values. The dose distribution was evaluated by the gamma method with parameters 3 mm and 3%. All differences of comparison of the MXX measurements and TPS calculations were within the range ±10% and the γ -index was less than 1 for 96% (or 97%, respectively) of the dose distribution in the plane at 10 mm distance from the source position. (authors)

  12. Simultaneous Detection of Different MicroRNA Types Using the ZIP-Code Array System

    Directory of Open Access Journals (Sweden)

    Sonja U. Weishaupt

    2013-01-01

    Full Text Available MicroRNAs (miRNAs are important negative regulators of gene expression. Their implication in tumorigenesis is based on their dysregulation in many human cancer diseases. Interestingly, in tumor cells, an altered ratio of precursor and mature miRNA levels has been described. Consequently, differences in miRNA type levels have a high potential as biomarkers and comparative high-throughput-based detection might permit a more accurate characterization of subtypes, especially in the case of very heterogeneous tumor entities. Several molecular methods exist for the detection of mature and precursor miRNAs. DNA microarrays are predestinated as a high-throughput method for comprehensive miRNA detection in tumors. However, the simultaneous array-based detection of both these miRNA types is limited because the mature miRNA sequence is identically present in both forms. Here we present a ZIP-code DNA microarray-based system in combination with a novel labeling approach, which enables the simultaneous detection of precursor and mature miRNAs in one single experiment. Using synthetic miRNA templates, we demonstrate the specificity of the method for the different miRNA types, as well as the detection range up to four orders of magnitude. Moreover, mature and precursor miRNAs were detected and validated in human tumor cells.

  13. Detection of mitochondrial DNA with the compact bead array sensor system (cBASS)

    Science.gov (United States)

    Mulvaney, Shawn P.; Ibe, Carol N.; Caldwell, Jane M.; Levine, Jay F.; Whitman, Lloyd J.; Tamanaha, Cy R.

    2009-02-01

    Enteric pathogens are a significant contaminant in surface waters used for recreation, fish and shellfish harvesting, crop irrigation, and human consumption. The need for water monitoring becomes more pronounced when industrial, agricultural, and residential lands are found in close proximity. Fecal contamination is particularly problematic and identification of the pollution source essential to remediation efforts. Standard monitoring for fecal contamination relies on indicator organisms, but the technique is too broad to identify the source of contamination. Instead, real-time PCR of mitochondrial DNA (mtDNA) is an emerging method for identification of the contamination source. Presented herein, we evaluate an alternative technology, the compact Bead Array Sensor System (cBASS®) and its assay approach Fluidic Force Discrimination (FFD), for the detection of mtDNA. Previously, we achieved multiplexed, attomolar detection of toxins and femtomolar detection of nucleic acids in minutes with FFD assays. More importantly, FFD assays are compatible with a variety of complex matrices and therefore potentially applicable for samples where the matrix would interfere with PCR amplification. We have designed a triplex assay for the NADH gene found in human, swine, and bovine mtDNA and demonstrated the specific detection of human mtDNA spiked into a waste water sample.

  14. Theoretical thermal dosimetry produced by an annular phased array system in CT-based patient models

    International Nuclear Information System (INIS)

    Theoretical calculations for the specific absorption rate (SAR) and the resulting temperature distributions produced by an annular phased array (APA) type system are made. The finite element numerical method is used in the formulation of both the electromagnetic (EM) and the thermal boundary value problems. A number of detailed patient models based on CT-scan data from the pelvic, visceral, and thoracic regions are generated to stimulate a variety of tumor locations and surrounding normal tissues. The SAR values from the EM solution are input into the bioheat transfer equation, and steady-rate temperature distributions are calculated for a wide variety of blood flow rates. Based on theoretical modeling, the APA shows no preferential heating of superficial over deep-seated tumors. However, in most cases satisfactory thermal profiles (therapeutic volume near 60%) are obtained in all three regions of the human trunk only for tumors with little or no blood flow. Unsatisfactory temperature patterns (therapeutic volume <50%) are found for tumors with moderate to high perfusion rates. These theoretical calculations should aid the clinician in the evaluation of the effectiveness of APA type devices in heating tumors located in the trunk region

  15. A temperature-based feedback control system for electromagnetic phased-array hyperthermia: theory and simulation

    International Nuclear Information System (INIS)

    A hybrid proportional-integral-in-time and cost-minimizing-in-space feedback control system for electromagnetic, deep regional hyperthermia is proposed. The unique features of this controller are that (1) it uses temperature, not specific absorption rate, as the criterion for selecting the relative phases and amplitudes with which to drive the electromagnetic phased-array used for hyperthermia and (2) it requires on-line computations that are all deterministic in duration. The former feature, in addition to optimizing the treatment directly on the basis of a clinically relevant quantity, also allows the controller to sense and react to time- and temperature-dependent changes in local blood perfusion rates and other factors that can significantly impact the temperature distribution quality of the delivered treatment. The latter feature makes it feasible to implement the scheme on-line in a real-time feedback control loop. This is in sharp contrast to other temperature optimization techniques proposed in the literature that generally involve an iterative approximation that cannot be guaranteed to terminate in a fixed amount of computational time. An example of its application is presented to illustrate the properties and demonstrate the capability of the controller to sense and compensate for local, time-dependent changes in blood perfusion rates

  16. Brain Computer Interface Learning for Systems Based on Electrocorticography and Intracortical Microelectrode Arrays

    Directory of Open Access Journals (Sweden)

    Shivayogi V Hiremath

    2015-06-01

    Full Text Available A brain-computer interface (BCI system transforms neural activity into control signals for external devices in real time. A BCI user needs to learn to generate specific cortical activity patterns to control external devices effectively. We call this process BCI learning, and it often requires significant effort and time. Therefore, it is important to study this process and develop novel and efficient approaches to accelerate BCI learning. This article reviews major approaches that have been used for BCI learning, including computer-assisted learning, co-adaptive learning, operant conditioning, and sensory feedback. We focus on BCIs based on electrocorticography and intracortical microelectrode arrays for restoring motor function. This article also explores the possibility of brain modulation techniques in promoting BCI learning, such as electrical cortical stimulation, transcranial magnetic stimulation, and optogenetics. Furthermore, as proposed by recent BCI studies, we suggest that BCI learning is in many ways analogous to motor and cognitive skill learning, and therefore skill learning should be a useful metaphor to model BCI learning.

  17. Real-time monitoring of cellular dynamics using a microfluidic cell culture system with integrated electrode array and potentiostat

    DEFF Research Database (Denmark)

    Zor, Kinga; Vergani, M.; Heiskanen, Arto;

    2011-01-01

    A versatile microfluidic, multichamber cell culture and analysis system with an integrated electrode array and potentiostat suitable for electrochemical detection and microscopic imaging is presented in this paper. The system, which allows on-line electrode cleaning and modification, was developed...... for real-time monitoring of cellular dynamics, exemplified in this work by monitoring of redox metabolism inside living yeast cells and dopamine release from PC12 cells....

  18. System for tunerless operation of a four-element phased array antenna for fast wave current drive

    International Nuclear Information System (INIS)

    A simple transmission line configuration for powering a four-element phased antenna array is described. This system, called the balanced feed configuration (BFC) is suitable for co- or counter- Fast Wave Current Drive (FWCD) applications. It has the property of presenting a constant matched load to the transmitter despite wide variations in the antenna load impedance without the use of variable tuning elements. This system has been implemented on a 2 MW 60 MHz FWCD antenna on the DIII-D tokamak

  19. Adaption of the Magnetometer Towed Array geophysical system to meet Department of Energy needs for hazardous waste site characterization

    International Nuclear Information System (INIS)

    This report documents US Department of Energy (DOE)-funded activities that have adapted the US Navy's Surface Towed Ordnance Locator System (STOLS) to meet DOE needs for a ''... better, faster, safer and cheaper ...'' system for characterizing inactive hazardous waste sites. These activities were undertaken by Sandia National Laboratories (Sandia), the Naval Research Laboratory, Geo-Centers Inc., New Mexico State University and others under the title of the Magnetometer Towed Array (MTA)

  20. Adaption of the Magnetometer Towed Array geophysical system to meet Department of Energy needs for hazardous waste site characterization

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, J.R. [Sandia National Labs., Albuquerque, NM (United States); McDonald, J.R. [Naval Research Lab., Washington, DC (United States); Russell, R.J. [Geo-Centers, Inc., Newton, MA (United States); Robertson, R. [Hughes Associates, Inc., Washington, DC (United States); Hensel, E. [New Mexico State Univ., Las Cruces, NM (United States). Dept. of Mechanical Engineering

    1995-10-01

    This report documents US Department of Energy (DOE)-funded activities that have adapted the US Navy`s Surface Towed Ordnance Locator System (STOLS) to meet DOE needs for a ``... better, faster, safer and cheaper ...`` system for characterizing inactive hazardous waste sites. These activities were undertaken by Sandia National Laboratories (Sandia), the Naval Research Laboratory, Geo-Centers Inc., New Mexico State University and others under the title of the Magnetometer Towed Array (MTA).

  1. Next Generation Extremely Large Solar Array System for NASA Exploration Missions Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed technology is a revolutionary solar array advancement that relies on a structurally optimized platform to provide unparalleled specific-performance and...

  2. Corporate array of micromachined dipoles on silicon wafer for 60 GHz communication systems

    KAUST Repository

    Sallam, M. O.

    2013-03-01

    In this paper, an antenna array operating at 60 GHz and realized on 0.675 mm thick silicon substrate is presented. The array is constructed using four micromachined half-wavelength dipoles fed by a corporate feeding network. Isolation between the antenna array and its feeding network is achieved via a ground plane. This arrangement leads to maximizing the broadside radiation with relatively high front-to-back ratio. Simulations have been carried out using both HFSS and CST, which showed very good agreement. Results reveal that the proposed antenna array has good radiation characteristics, where the directivity, gain, and radiation efficiency are around 10.5 dBi, 9.5 dBi, and 79%, respectively. © 2013 IEEE.

  3. System Realization of Broad Band Digital Beam Forming for Digital Array Radar

    Directory of Open Access Journals (Sweden)

    Wang Feng

    2013-09-01

    Full Text Available Broad band Digital Beam Forming (DBF is the key technique for the realization of Digital Array Radar (DAR. We propose the method of combination realization of the channel equalization and DBF time delay filter function by using adaptive Sample Matrix Inversion algorithm. The broad band DBF function is realized on a new DBF module based on parallel fiber optic engines and Field Program Gate Array (FPGA. Good performance is achieved when it is used to some radar products.

  4. Optical SideBand Filtering in an optical beam forming system for phased-array antennas

    OpenAIRE

    Peña Hevilla, J.

    2007-01-01

    Directionally controlled antennas — or phased array antennas — are widely used in many mobile telecom markets and recently they have a space in consumer products and transport vehicles, as an aircraft, ships, etcetera. In this project, the field of interest will be the satellite comunications between a satellite transmitter and an aircraft using a DVB-S signal. Smart antennas in either transmission or reception have a directionally controlled radiation beam based on multiple antenna array ele...

  5. A high speed digital data acquisition system for the Indian National Gamma Array at Tata Institute of Fundamental Research

    Science.gov (United States)

    Palit, R.; Saha, S.; Sethi, J.; Trivedi, T.; Sharma, S.; Naidu, B. S.; Jadhav, S.; Donthi, R.; Chavan, P. B.; Tan, H.; Hennig, W.

    2012-07-01

    A digital data acquisition system for the Compton suppressed clover detector array has been implemented at the TIFR-BARC accelerator facility for the high resolution gamma ray spectroscopy using the Pixie-16 Digital Gamma Finder modules by XIA LLC. This system has a provision for simultaneous digitization of 96 preamplifier signals of high purity germanium crystals. The energy and timing characteristics of the clover detectors have been investigated in detail. In-beam data has been collected both in singles and in the coincidence mode. The system has been tested with 64 channels with each of the 64 crystals having an event rate up to 5 kHz and 2-fold clover coincidence rate up to 15 kHz. The use of the digital data acquisition system has improved the high counting rate handling capabilities for the clover array. Conventional systems with analog shaping are being replaced by digital system that provides higher throughput, better energy resolution and better stability for the multi-detector Compton suppressed clover array.

  6. A high speed digital data acquisition system for the Indian National Gamma Array at Tata Institute of Fundamental Research

    International Nuclear Information System (INIS)

    A digital data acquisition system for the Compton suppressed clover detector array has been implemented at the TIFR-BARC accelerator facility for the high resolution gamma ray spectroscopy using the Pixie-16 Digital Gamma Finder modules by XIA LLC. This system has a provision for simultaneous digitization of 96 preamplifier signals of high purity germanium crystals. The energy and timing characteristics of the clover detectors have been investigated in detail. In-beam data has been collected both in singles and in the coincidence mode. The system has been tested with 64 channels with each of the 64 crystals having an event rate up to 5 kHz and 2-fold clover coincidence rate up to 15 kHz. The use of the digital data acquisition system has improved the high counting rate handling capabilities for the clover array. Conventional systems with analog shaping are being replaced by digital system that provides higher throughput, better energy resolution and better stability for the multi-detector Compton suppressed clover array.

  7. Electronics and data acquisition system of the extensive air shower detector array at the University of Puebla

    Science.gov (United States)

    Perez, E.; Salazar, H.; Villasenor, L.; Martinez, O.; Conde, R.; Murrieta, T.

    Field programmable gate arrays (FPGAs) are playing an increasing role in DAQ systems in cosmic ray experiments due to their high speed and integration and their low cost and low power comsumption. In this paper we describe in detail the new electronics and data acquisition system based on FPGA boards of the extensive air shower detector array built in the Campus of the University of Puebla. The purpose of this detector array is to measure the energy and arrival direction of primary cosmic rays with energies around 1015 eV. The array consists of 10 liquid scintillator detectors and 6 water Cherenkov detectors (of 1.86 m2 cross section), distributed in a square grid with a detector spacing of 20 m over an area of 4000 m2. The electronics described also makes use of analog to digital converters with a resolution of 10 bits and sampling speeds of 100 MS/s to digitize the PMT signals. We also discuss the advantages of discriminating the PMT signals inside the FPGAs with respect to the conventional use of dedicated discrimination circuits.

  8. The Fermilab Advanced Computer Program Multi-Array Processor System (ACPMAPS): A site oriented supercomputer for theoretical physics

    International Nuclear Information System (INIS)

    The ACP Multi-Array Processor System (ACPMAPS) is a highly cost effective, local memory parallel computer designed for floating point intensive grid based problems. The processing nodes of the system are single board array processors based on the FORTRAN and C programmable Weitek XL chip set. The nodes are connected by a network of very high bandwidth 16 port crossbar switches. The architecture is designed to achieve the highest possible cost effectiveness while maintaining a high level of programmability. The primary application of the machine at Fermilab will be lattice gauge theory. The hardware is supported by a transparent site oriented software system called CANOPY which shields theorist users from the underlying node structure. (author). 4 refs, 2 figs

  9. Development of measurement system for radiation effect on static random access memory based field programmable gate array

    International Nuclear Information System (INIS)

    Based on the detailed investigation in field programmable gate array(FPGA) radiation effects theory, a measurement system for radiation effects on static random access memory(SRAM)-based FPGA was developed. The testing principle of internal memory, function and power current was introduced. The hardware and software implement means of system were presented. Some important parameters for radiation effects on SRAM-based FPGA, such as configuration RAM upset section, block RAM upset section, function fault section and single event latchup section can be gained with this system. The transmission distance of the system can be over 50 m and the maximum number of tested gates can reach one million. (authors)

  10. Anion analysis using capillary electrophoresis in the Halden reactor

    International Nuclear Information System (INIS)

    A significant investment has been made over the last decade in water chemistry analysis capability at the Halden Reactor, reflecting both the need to maintain system reliability and to provide chemical analyses for the increasing number of corrosion and chemistry-related experiments being performed in the reactor. Control of concentrations of anionic species (chloride, sulphate and nitrate) is of crucial importance in reducing the potential of stainless steel components to undergo stress corrosion cracking. Currently at Halden, samples must be taken from the coolant in the reactor itself, several auxiliary systems and approximately 10 test loop systems. Previously, anion analyses were performed using ion chromatography. In 1996, this technique was superseded by capillary electrophoresis since the latter has several advantages over the former, including speed of analysis. This paper will present operational experience of using capillary electrophoresis from two different suppliers. A discussion of the advantages and disadvantages of the technique over ion chromatography is included. (author)

  11. Tissue matrix arrays for high-throughput screening and systems analysis of cell function.

    Science.gov (United States)

    Beachley, Vince Z; Wolf, Matthew T; Sadtler, Kaitlyn; Manda, Srikanth S; Jacobs, Heather; Blatchley, Michael R; Bader, Joel S; Pandey, Akhilesh; Pardoll, Drew; Elisseeff, Jennifer H

    2015-12-01

    Cell and protein arrays have demonstrated remarkable utility in the high-throughput evaluation of biological responses; however, they lack the complexity of native tissue and organs. Here we spotted tissue extracellular matrix (ECM) particles as two-dimensional (2D) arrays or incorporated them with cells to generate three-dimensional (3D) cell-matrix microtissue arrays. We then investigated the responses of human stem, cancer and immune cells to tissue ECM arrays originating from 11 different tissues. We validated the 2D and 3D arrays as representative of the in vivo microenvironment by means of quantitative analysis of tissue-specific cellular responses, including matrix production, adhesion and proliferation, and morphological changes after culture. The biological outputs correlated with tissue proteomics, and network analysis identified several proteins linked to cell function. Our methodology enables broad screening of ECMs to connect tissue-specific composition with biological activity, providing a new resource for biomaterials research and further understanding of regeneration and disease mechanisms. PMID:26480475

  12. Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study.

    Science.gov (United States)

    Wu, Tianfu; Ding, Huihua; Han, Jie; Arriens, Cristina; Wei, Chungwen; Han, Weilu; Pedroza, Claudia; Jiang, Shan; Anolik, Jennifer; Petri, Michelle; Sanz, Ignacio; Saxena, Ramesh; Mohan, Chandra

    2016-07-01

    A discovery study was carried out where serum samples from 22 systemic lupus erythematosus (SLE) patients and matched healthy controls were hybridized to antibody-coated glass slide arrays that interrogated the level of 274 human proteins. On the basis of these screens, 48 proteins were selected for ELISA-based validation in an independent cohort of 28 SLE patients. Whereas AXL, ferritin, and sTNFRII were significantly elevated in patients with active lupus nephritis (LN) relative to SLE patients who were quiescent, other molecules such as OPN, sTNFRI, sTNFRII, IGFBP2, SIGLEC5, FAS, and MMP10 exhibited the capacity to distinguish SLE from healthy controls with ROC AUC exceeding 90%, all with p serum markers were next tested in a cohort of 45 LN patients, where serum was obtained at the time of renal biopsy. In these patients, sTNFRII exhibited the strongest correlation with eGFR (r = -0.50, p = 0.0014) and serum creatinine (r = 0.57, p = 0.0001), although AXL, FAS, and IGFBP2 also correlated with these clinical measures of renal function. When concurrent renal biopsies from these patients were examined, serum FAS, IGFBP2, and TNFRII showed significant positive correlations with renal pathology activity index, while sTNFRII displayed the highest correlation with concurrently scored renal pathology chronicity index (r = 0.57, p = 0.001). Finally, in a longitudinal cohort of seven SLE patients examined at ∼3 month intervals, AXL, ICAM-1, IGFBP2, SIGLEC5, sTNFRII, and VCAM-1 demonstrated the ability to track with concurrent disease flare, with significant subject to subject variation. In summary, serum proteins have the capacity to identify patients with active nephritis, flares, and renal pathology activity or chronicity changes, although larger longitudinal cohort studies are warranted. PMID:27211902

  13. Portable capillary electrophoresis-system for on-site food analysis with lab-on-a-chip based contactless conductivity detection

    Science.gov (United States)

    Gärtner, Claudia; Sewart, René; Klemm, Richard; Becker, Holger

    2014-06-01

    A portable analytical system for the characterization of liquid environmental samples and beverages in food control was realized. The key element is the implementation of contactless conductivity detection on lab-on-a-chip basis ensuring the system to be operated in a label free mode. Typical target molecules such as small ionic species like Li+, Na+, K+, SO4 2- or NO3-, organic acids in wine whose concentration and ratio to each other documents the wine quality, or caffeine or phosphate in coke were detected. Results from sample matrices like various beverages as water, cola, tea, wine and milk, water from heaters, environmental samples and blood will be presented.

  14. Photovoltaic properties of the copper-phthalocyanine and ZnO nanorod array system affected by ethanol

    International Nuclear Information System (INIS)

    Well-aligned ZnO nanorod array, fabricated on conductive indium-tin-oxide (ITO) substrate by wet chemical bath deposition (CBD) method, was characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD). Surface photovoltage (SPV) technique was employed to study the photovoltaic properties of the copper-phthalocyanine (CuPc) and ZnO nanorod array system affected by ethanol. Prior to ethanol adsorption, two pronounced SPV response bands were exhibited for this system in the range 300-410 and 540-760 nm, respectively. Post-adsorption measurements reveal that the SPV intensity of the former band is enhanced, while that of the latter band is suppressed if ethanol was used to modify CuPc surface. Moreover, both of the SPV intensity of two response bands is enhanced if ethanol was used to modify ZnO and CuPc interface. Mechanisms of these phenomena were suggested.

  15. Contactless conductivity detector for microchip capillary electrophoresis

    Science.gov (United States)

    Pumera, Martin; Wang, Joseph; Opekar, Frantisek; Jelinek, Ivan; Feldman, Jason; Lowe, Holger; Hardt, Steffen; Svehla, D. (Principal Investigator)

    2002-01-01

    A microfabricated electrophoresis chip with an integrated contactless conductivity detection system is described. The new contactless conductivity microchip detector is based on placing two planar sensing aluminum film electrodes on the outer side of a poly(methyl methacrylate) (PMMA) microchip (without contacting the solution) and measuring the impedance of the solution in the separation channel. The contactless route obviates problems (e.g., fouling, unwanted reactions) associated with the electrode-solution contact, offers isolation of the detection system from high separation fields, does not compromise the separation efficiency, and greatly simplifies the detector fabrication. Relevant experimental variables, such as the frequency and amplitude of the applied ac voltage or the separation voltage, were examined and optimized. The detector performance was illustrated by the separation of potassium, sodium, barium, and lithium cations and the chloride, sulfate, fluoride, acetate, and phosphate anions. The response was linear (over the 20 microM-7 mM range) and reproducible (RSD = 3.4-4.9%; n = 10), with detection limits of 2.8 and 6.4 microM (for potassium and chloride, respectively). The advantages associated with the contactless conductivity detection, along with the low cost of the integrated PMMA chip/detection system, should enhance the power and scope of microfluidic analytical devices.

  16. Estimating the DNA strand breakage using a fuzzy inference system and agarose gel electrophoresis, a case study with toothed carp Aphanius sophiae exposed to cypermethrin.

    Science.gov (United States)

    Poorbagher, Hadi; Moghaddam, Maryam Nasrollahpour; Eagderi, Soheil; Farahmand, Hamid

    2016-07-01

    The DNA breakage has been widely used in ecotoxicological studies to investigate effects of pesticides in fishes. The present study used a fuzzy inference system to quantify the breakage of DNA double strand in Aphanius sophiae exposed to the cypermethrin. The specimens were adapted to different temperatures and salinity for 14 days and then exposed to cypermethrin. DNA of each specimens were extracted, electrophoresed and photographed. A fuzzy system with three input variables and 27 rules were defined. The pixel value curve of DNA on each gel lane was obtained using ImageJ. The DNA breakage was quantified using the pixel value curve and fuzzy system. The defuzzified values were analyzed using a three-way analysis of variance. Cypermethrin had significant effects on DNA breakage. Fuzzy inference systems can be used as a tool to quantify the breakage of double strand DNA. DNA double strand of the gill of A. sophiae is sensitive enough to be used to detect cypermethrin in surface waters in concentrations much lower than those reported in previous studies. PMID:27000282

  17. Single Event Test Methodologies and System Error Rate Analysis for Triple Modular Redundant Field Programmable Gate Arrays

    Science.gov (United States)

    Allen, Gregory; Edmonds, Larry D.; Swift, Gary; Carmichael, Carl; Tseng, Chen Wei; Heldt, Kevin; Anderson, Scott Arlo; Coe, Michael

    2010-01-01

    We present a test methodology for estimating system error rates of Field Programmable Gate Arrays (FPGAs) mitigated with Triple Modular Redundancy (TMR). The test methodology is founded in a mathematical model, which is also presented. Accelerator data from 90 nm Xilins Military/Aerospace grade FPGA are shown to fit the model. Fault injection (FI) results are discussed and related to the test data. Design implementation and the corresponding impact of multiple bit upset (MBU) are also discussed.

  18. Analytical Model of Non-Imaging Planar Concentrator for the Application in Dense-Array Concentrator Photovoltaic System

    OpenAIRE

    Wong, Chee Woon; Chong, Kok Keong; Yew, Tiong Keat

    2014-01-01

    Instead of using numerical simulation method that is relatively slow if accuracy is required, an analytical model has been proposed to analyze the optical characteristic of Non-Imaging Planar Concentrator (NIPC) for the application in dense-array concentrator photovoltaic (DACPV) system. Several trigonometry equations have been solved to determine the maximum solar concentration ratio, uniform illumination area and energy within the uniform area by varying the focal distance. The concentratio...

  19. 20-element HgI2 energy dispersive x-ray array detector system

    International Nuclear Information System (INIS)

    This paper describes recent progress in the development of HgI2 energy dispersive x-ray arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20-element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-Kalpha) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken form diluted samples simulating proteins with nickel

  20. 20 element HgI sub 2 energy dispersive x-ray array detector system

    Energy Technology Data Exchange (ETDEWEB)

    Iwanczyk, J.A.; Dorri, N.; Wang, M.; Szczebiot, R.W.; Dabrowski, A.J. (Xsirius, Inc., Marina Del Rey, CA (United States)); Hedman, B.; Hodgson, K.O. (Stanford Univ., CA (United States). Stanford Synchrotron Radiation Lab.); Patt, B.E. (EG and G Energy Measurements, Inc., Goleta, CA (United States))

    1991-01-01

    This paper describes recent progress in the development of HgI{sub 2} energy dispersive x-ray detector arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20 element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-K{sub a}) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken from diluted samples simulating proteins with nickel.

  1. 20 element HgI{sub 2} energy dispersive x-ray array detector system

    Energy Technology Data Exchange (ETDEWEB)

    Iwanczyk, J.A.; Dorri, N.; Wang, M.; Szczebiot, R.W.; Dabrowski, A.J. [Xsirius, Inc., Marina Del Rey, CA (United States); Hedman, B.; Hodgson, K.O. [Stanford Univ., CA (United States). Stanford Synchrotron Radiation Lab.; Patt, B.E. [EG and G Energy Measurements, Inc., Goleta, CA (United States)

    1991-12-31

    This paper describes recent progress in the development of HgI{sub 2} energy dispersive x-ray detector arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20 element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-K{sub a}) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken from diluted samples simulating proteins with nickel.

  2. 20-element HgI[sub 2] energy dispersive x-ray array detector system

    Energy Technology Data Exchange (ETDEWEB)

    Iwanczyk, J.S.; Dorri, N.; Wang, M.; Szczebiot, R.W.; Dabrowski, A.J. (Xsirius, Inc., Marina del Ray, CA (United States)); Hedman, B.; Hodgson, K.O. (Stanford Univ., CA (United States). Stanford Synchrotron Radiation Lab.); Patt, B.E. (EG and G Energy Measurements, Inc., Goleta, CA (United States))

    1992-10-01

    This paper describes recent progress in the development of HgI[sub 2] energy dispersive x-ray arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20-element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-K[sub alpha]) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken form diluted samples simulating proteins with nickel.

  3. 20 element HgI2 energy dispersive x-ray array detector system

    International Nuclear Information System (INIS)

    This paper describes recent progress in the development of HgI2 energy dispersive x-ray detector arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20 element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-Ka) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken from diluted samples simulating proteins with nickel

  4. The 20 element HgI2 energy dispersive x ray array detector system

    Science.gov (United States)

    Iwanczyk, J. A.; Dorri, N.; Wang, M.; Szczebiot, R. W.; Dabrowski, A. J.; Hedman, B.; Hodgson, K. O.; Patt, B. E.

    1991-11-01

    This paper describes recent progress in the development of HgI2 energy dispersive x-ray detector arrays and associated miniaturized processing electronics for synchrotron radiation research applications. The experimental results with a 20 element array detector were obtained under realistic synchrotron beam conditions at SSRL. An energy resolution of 250 eV (FWHM) at 5.9 keV (Mn-K(sub a)) was achieved. Energy resolution and throughput measurements versus input count rate and energy of incoming radiation have been measured. Extended X-ray Absorption Fine Structure (EXAFS) spectra were taken from diluted samples simulating proteins with nickel.

  5. Space satellite power system. [conversion of solar energy by photovoltaic solar cell arrays

    Science.gov (United States)

    Glaser, P. E.

    1974-01-01

    The concept of a satellite solar power station was studied. It is shown that it offers the potential to meet a significant portion of future energy needs, is pollution free, and is sparing of irreplaceable earth resources. Solar energy is converted by photovoltaic solar cell arrays to dc energy which in turn is converted into microwave energy in a large active phased array. The microwave energy is beamed to earth with little attenuation and is converted back to dc energy on the earth. Economic factors are considered.

  6. Microcomputer Based System to control the Load of a Capacitor Array in the TJ-1 Tokamak; Sistema de Control de Carga de Condensadores del TJ-1

    Energy Technology Data Exchange (ETDEWEB)

    Alberdi, J.; Asenso, L.; Sanz, J. A.

    1990-07-01

    The power to create the magnetic fields in the TJ-1 Tokamak is provides by an array of 16 capacitor sets. The total capacity of this array is 8. 1F. This work describes a computer system based on the Motorola M-6800 micro- processor which controls the load of the capacitor set and stablished the conditions for the reactor trigger. (Author)

  7. An ultra-wideband radar imaging system using a two-dimensional multiple-input multiple-output (MIMO) transducer array

    NARCIS (Netherlands)

    Fortuny-Guasch, J.; Martinez, A.; Yarovoy, A.; Zhuge, X.; Lerat, J.M.; Duchesne, L.

    2011-01-01

    A radar transducer array (12) for an ultra-wideband imaging radar system (10) operating at a reference wavelength ?c comprises transmission antenna elements (14) or reception antenna elements and reception antenna elements (16), which are located at specific locations of the array plane in such a wa

  8. Array for detecting microbes

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, Gary L.; DeSantis, Todd D.

    2014-07-08

    The present embodiments relate to an array system for detecting and identifying biomolecules and organisms. More specifically, the present embodiments relate to an array system comprising a microarray configured to simultaneously detect a plurality of organisms in a sample at a high confidence level.

  9. Capillary electrophoresis microchip coupled with on-line chemiluminescence detection

    International Nuclear Information System (INIS)

    In the present work, chemiluminescence detection was integrated with capillary electrophoresis microchip. The microchip was designed on the principle of flow-injection chemiluminescence system and capillary electrophoresis. It has three main channels, five reservoirs and a detection cell. As model samples, dopamine and catechol were separated and detected using a permanganate chemiluminescent system on the prepared microchip. The samples were electrokinetically injected into the double-T cross section, separated in the separation channel, and then oxidized by chemiluminescent reagent delivered by a home-made micropump to produce light in the detection cell. The electroosmotic flow could be smoothly coupled with the micropump flow. The detection limits for dopamine and catechol were 20.0 and 10.0 μM, respectively. Successful separation and detection of dopamine and catechol demonstrated the distinct advantages of integration of chemiluminescent detection on a microchip for rapid and sensitive analysis

  10. Capillary electrophoresis electrospray ionization mass spectrometry interface

    Science.gov (United States)

    Smith, Richard D.; Severs, Joanne C.

    1999-01-01

    The present invention is an interface between a capillary electrophoresis separation capillary end and an electrospray ionization mass spectrometry emitter capillary end, for transporting an anolyte sample from a capillary electrophoresis separation capillary to a electrospray ionization mass spectrometry emitter capillary. The interface of the present invention has: (a) a charge transfer fitting enclosing both of the capillary electrophoresis capillary end and the electrospray ionization mass spectrometry emitter capillary end; (b) a reservoir containing an electrolyte surrounding the charge transfer fitting; and (c) an electrode immersed into the electrolyte, the electrode closing a capillary electrophoresis circuit and providing charge transfer across the charge transfer fitting while avoiding substantial bulk fluid transfer across the charge transfer fitting. Advantages of the present invention have been demonstrated as effective in providing high sensitivity and efficient analyses.

  11. Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation

    OpenAIRE

    Roghaye Khodadadi; Azim Khajeali; Alireza Farajollahi; Parisa Hajalioghli; Noorallah Raeisi

    2015-01-01

    Introduction: The main objective of this study was to investigate the possibility of replacing electrophoresis cross-linker with non-electrophoresis N, N′-methylenebisacrylamide (BIS) in N-isopropyl acrylamide (NIPAM) polymer gel and its possible effect on dose response. Methods: NIPAM polymer gel was prepared from non-electrophoresis grade BIS and the relaxation rate (R2) was measured by MR imaging after exposing the gel to gamma radiation from Co-60 source. To compare the response of t...

  12. Preprocessing of 1D gel electrophoresis image

    OpenAIRE

    Hlavatý, Matej

    2015-01-01

    Gel electrophoresis is an important method used for separation and analysis of macromolecules with electric potential. This well-established method has a big potential in medicine and science, however, the output images often suffer from distortion. This work describes several known sources of distortion and elaborates on existing methods of the track detection in gel electrophoresis. The core of this thesis introduces a new method to detect individual tracks and image pre-processing based on...

  13. Capillary Electrophoresis coupled with Automated Fraction Collection

    OpenAIRE

    Huge, Bonnie Jaskowski; Flaherty, Ryan; Dada, Oluwatosin O.; Dovichi, Norman J.

    2014-01-01

    A fraction collector based on a drop-on-demand ink-jet printer was developed to interface capillary zone electrophoresis with a 96 well microtiter plate. We first evaluated the performance of the collector by using capillary zone electrophoresis to analyze a 1 mM solution of tetramethylrhodamine; a fluorescent microtiter plate reader was then used to detect the analyte and characterize fraction carryover between wells. Relative standard deviation in peak height was 20% and the relative standa...

  14. Polyacrylamide gel electrophoresis of isoenzymes from Entamoeba species.

    OpenAIRE

    Mathews, H M; Moss, D M; Healy, G R; Visvesvara, G S

    1983-01-01

    In this preliminary report, we describe a polyacrylamide gel electrophoresis technique for the resolution of isoenzyme patterns of four isolates of Entamoeba histolytica and one isolate of Entamoeba coli. Our findings were similar to previous findings for three enzyme systems: maleic enzyme (malate dehydrogenase [EC 1.1.1.40]), hexokinase (EC 2.7.1.1), and phosphoglucomutase (EC 2.7.5.1). We found preliminary evidence that glucosephosphate isomerase (EC 5.3.1.9) may also differentiate invasiv...

  15. Optimized photonic crystal fibers supporting efficient capillary electrophoresis

    Science.gov (United States)

    Calcerrada, M.; García-Ruiz, C.; Roy, P.; Gonzalez-Herraez, M.

    2013-05-01

    In this paper we present preliminary results on the use of Photonic Crystal Fibers (PCFs) in a conventional capillary electrophoresis system to separate and detect fluorescent species. PCFs show interesting advantages over conventional capillaries for this application, including larger surface-to-volume ratio and potential for higher resolution with comparable sensitivity. Our results illustrate some of these advantages, and we point out the need for stringent tolerances in the fabrication of specific PCFs for this application.

  16. The readout and control system of the mid-size telescope prototype of the Cherenkov telescope array

    International Nuclear Information System (INIS)

    The Cherenkov Telescope Array (CTA) is one of the major ground-based astronomy projects being pursued and will be the largest facility for ground-based y-ray observations ever built. CTA will consist of two arrays: one in the Northern hemisphere composed of about 20 telescopes, and the other one in the Southern hemisphere composed of about 100 telescopes, both arrays containing telescopes of different type and size. A prototype for the Mid-Size Telescope (MST) with a diameter of 12 m has been installed in Berlin and is currently being commissioned. This prototype is composed of a mechanical structure, a drive system and mirror facets mounted with powered actuators to enable active control. Five Charge-Coupled Device (CCD) cameras, and a wide set of sensors allow the evaluation of the performance of the instrument. The design of the control software is following concepts and tools under evaluation within the CTA consortium in order to provide a realistic test-bed for the middleware: 1) The readout and control system for the MST prototype is implemented with the Atacama Large Millimeter/submillimeter Array (ALMA) Common Software (ACS) distributed control middleware; 2) the OPen Connectivity-Unified Architecture (OPC UA) is used for hardware access; 3) the document oriented MongoDB database is used for an efficient storage of CCD images, logging and alarm information: and 4) MySQL and MongoDB databases are used for archiving the slow control monitoring data and for storing the operation configuration parameters. In this contribution, the details of the implementation of the control system for the MST prototype telescope are described.

  17. The readout and control system of the mid-size telescope prototype of the Cherenkov Telescope Array

    Science.gov (United States)

    Oya, I.; Anguner, O.; Behera, B.; Birsin, E.; Fuessling, M.; Melkumyan, D.; Schmidt, T.; Schwanke, U.; Sternberger, R.; Wegner, P.; Wiesand, S.; Cta Consortium,the

    2014-06-01

    The Cherenkov Telescope Array (CTA) is one of the major ground-based astronomy projects being pursued and will be the largest facility for ground-based y-ray observations ever built. CTA will consist of two arrays: one in the Northern hemisphere composed of about 20 telescopes, and the other one in the Southern hemisphere composed of about 100 telescopes, both arrays containing telescopes of different type and size. A prototype for the Mid-Size Telescope (MST) with a diameter of 12 m has been installed in Berlin and is currently being commissioned. This prototype is composed of a mechanical structure, a drive system and mirror facets mounted with powered actuators to enable active control. Five Charge-Coupled Device (CCD) cameras, and a wide set of sensors allow the evaluation of the performance of the instrument. The design of the control software is following concepts and tools under evaluation within the CTA consortium in order to provide a realistic test-bed for the middleware: 1) The readout and control system for the MST prototype is implemented with the Atacama Large Millimeter/submillimeter Array (ALMA) Common Software (ACS) distributed control middleware; 2) the OPen Connectivity-Unified Architecture (OPC UA) is used for hardware access; 3) the document oriented MongoDB database is used for an efficient storage of CCD images, logging and alarm information: and 4) MySQL and MongoDB databases are used for archiving the slow control monitoring data and for storing the operation configuration parameters. In this contribution, the details of the implementation of the control system for the MST prototype telescope are described.

  18. An Array-based Approach to Modelling Production Management System Architectures

    DEFF Research Database (Denmark)

    Falster, Peter

    geometrical thinking. Accordingly, elements from measurement and array theory are introduced, but in a more abstract way than traditionally connected with 3D-geometry. The paper concludes that a few set of concepts, like products, resources, activities, events, stages, etc. can be synthesized and analogies...

  19. Procedures for two-dimensional electrophoresis of proteins

    Energy Technology Data Exchange (ETDEWEB)

    Tollaksen, S.L.; Giometti, C.S.

    1996-10-01

    High-resolution two-dimensional gel electrophoresis (2DE) of proteins, using isoelectric focusing in the first dimension and sodium dodecyl sulfate/polyacrylamide gel electrophoresis (SDS-PAGE) in the second, was first described in 1975. In the 20 years since those publications, numerous modifications of the original method have evolved. The ISO-DALT system of 2DE is a high-throughput approach that has stood the test of time. The problem of casting many isoelectric focusing gels and SDS-PAGE slab gels (up to 20) in a reproducible manner has been solved by the use of the techniques and equipment described in this manual. The ISO-DALT system of two-dimensional gel electrophoresis originated in the late 1970s and has been modified many times to improve its high-resolution, high-throughput capabilities. This report provides the detailed procedures used with the current ISO-DALT system to prepare, run, stain, and photograph two-dimensional gels for protein analysis.

  20. Software design for the control system for Small-Size Telescopes with single-mirror of the Cherenkov Telescope Array

    CERN Document Server

    :,; Błocki, J; Bogacz, L; Borkowski, J; Bulik, T; Cadoux, F; Christov, A; Curyło, M; della Volpe, D; Dyrda, M; Favre, Y; Frankowski, A; Grudnik, Ł; Grudzińska, M; Heller, M; Idźkowski, B; Jamrozy, M; Janiak, M; Kasperek, J; Lalik, K; Lyard, E; Mach, E; Mandat, D; Marszałek, A; Michałowski, J; Moderski, R; Rameez, M; Montaruli, T; Neronov, A; Niemiec, J; Ostrowski, M; Paśko, P; Pech, M; Porcelli, A; Prandini, E; Rajda, P; Schioppa, E jr; Schovanek, P; Seweryn, K; Skowron, K; Sliusar, V; Sowiński, M; Stawarz, Ł; Stodulska, M; Stodulski, M; Pujadas, I Troyano; Toscano, S; Walter, R; Wiȩcek, M; Zagdański, A; Ziȩtara, K; Zychowski, P

    2015-01-01

    The Small-Size Telescope with single-mirror (SST-1M) is a 4 m Davies-Cotton telescope and is among the proposed telescope designs for the Cherenkov Telescope Array (CTA). It is conceived to provide the high-energy ($>$ few TeV) coverage. The SST-1M contains proven technology for the telescope structure and innovative electronics and photosensors for the camera. Its design is meant to be simple, low-budget and easy-to-build industrially. Each device subsystem of an SST-1M telescope is made visible to CTA through a dedicated industrial standard server. The software is being developed in collaboration with the CTA Medium-Size Telescopes to ensure compatibility and uniformity of the array control. Early operations of the SST-1M prototype will be performed with a subset of the CTA central array control system based on the Alma Common Software (ACS). The triggered event data are time stamped, formatted and finally transmitted to the CTA data acquisition. The software system developed to control the devices of an SS...

  1. OpenADAM: an open source genome-wide association data management system for Affymetrix SNP arrays

    Directory of Open Access Journals (Sweden)

    Sham P C

    2008-12-01

    Full Text Available Abstract Background Large scale genome-wide association studies have become popular since the introduction of high throughput genotyping platforms. Efficient management of the vast array of data generated poses many challenges. Description We have developed an open source web-based data management system for the large amount of genotype data generated from the Affymetrix GeneChip® Mapping Array and Affymetrix Genome-Wide Human SNP Array platforms. The database supports genotype calling using DM, BRLMM, BRLMM-P or Birdseed algorithms provided by the Affymetrix Power Tools. The genotype and corresponding pedigree data are stored in a relational database for efficient downstream data manipulation and analysis, such as calculation of allele and genotype frequencies, sample identity checking, and export of genotype data in various file formats for analysis using commonly-available software. A novel method for genotyping error estimation is implemented using linkage disequilibrium information from the HapMap project. All functionalities are accessible via a web-based user interface. Conclusion OpenADAM provides an open source database system for management of Affymetrix genome-wide association SNP data.

  2. Triggered mesa-top single photon emitter arrays and on-chip integration with dielectric nanoantenna-waveguide systems

    CERN Document Server

    Zhang, Jiefei; Lu, Siyuan; Madhukar, Anupam

    2016-01-01

    Nanophotonic quantum information processing systems require spatially ordered, spectrally uniform single photon sources (SPSs), integrated on-chip with co-designed light manipulating elements providing emission rate enhancement, emitted photon guidance, and lossless propagation. Towards this objective, we introduce and report on systems comprising an SPS array with each SPS surrounded by a dielectric building block (DBB) based multifunctional light manipulation unit (LMU). For the SPS array, we report triggered single photon emission at 77K from GaAs(001)/InGaAs single quantum dots (SQDs) grown selectively on top of nanomesas using the approach of substrate-encoded size-reducing epitaxy (SESRE). Systematic temperature and power dependent photoluminescence (PL), PL excitation, time-resolved PL, and emission statistics studies reveal high spectral uniformity and single photon emission at 77.4K with $g^{(2)}$(0) of 0.24 $\\pm$ 0.07. The SESRE based SPS arrays, following growth of a planarizing overlayer, are read...

  3. A charge-coupled-device camera image analysis system for quantifying DNA distributions in agarose gels after pulsed-field gel electrophoresis

    International Nuclear Information System (INIS)

    A charge-coupled-device camera system was coupled to a personal computer and, with uniformity in illumination and detection (within 4-8%) along each lane, was used for quantifying the distribution of DNA molecules that migrate from the PFGE well (plug) into the lane at distances varying from 1 to 50 mm (with 0.5 mm/pixel). By using a specially designed transmission filter for transmitting 470-725 nm fluorescence from ethidium bromide-stained DNA while eliminating most of the fluorescence (3H]dThd. However, scattering of fluorescence from one lane into an adjacent lane 3 mm away and as far as 10 mm from the plug into the lane presented a problem. This problem was overcome by using a form with slots to cover every other lane when the images were obtained and either (1) cutting the lane from the plug and moving it 15 mm away or (2) imaging the intact gel and applying a correction for ∼ 7% of the fluorescence from the plug tailing out ∼ 10 mm beyond the first 1 mm in the lane. In addition, the following were required: (1) carefully controlled staining and destaining procedures, and (2) a low background that is obtained as an average uniform background in each lane 5 mm beyond where DNA migration stops. 31 refs., 7 figs

  4. Using the polymerase chain reaction coupled with denaturing gradient gel electrophoresis to investigate the association between bacterial translocation and systemic inflammatory response syndrome in predicted acute severe pancreatitis

    Institute of Scientific and Technical Information of China (English)

    Callum B Pearce; Vitaly Zinkevich; Iwona Beech; Viera Funjika; Ana Garcia Ruiz; Afraa Aladawi; Hamish D Duncan

    2005-01-01

    AIM: To investigate the use of PCR and DGGE to investigate the association between bacterial translocation and systemic inflammatory response syndrome in predicted severe AP.METHODS: Patients with biochemical and clinical evidence of acute pancreatitis and an APACHE Ⅱ score ≥8 were enrolled. PCR and DGGE were employed to detect bacterial translocation in blood samples collected on d1,3, and 8 after the admission. Standard microbial blood cultures were taken when there was clinical evidence of sepsis or when felt to be clinically indicated by the supervising team.RESULTS: Six patients were included. Of all the patients investigated, only one developed septic complications;the others had uneventful illness. Bacteria were detected using PCR in 4 of the 17 collected blood samples. The patient with sepsis was PCR-positive in two samples (taken on d 1 and 3), despite three negative blood cultures. Using DGGE and specific primers, the bacteria in all blood specimens which tested positive for the presence of bacterial DNA were identified as E coli.CONCLUSION: Our study confirmed thatunlike traditional microbiological techniques, PCR can detect the presence of bacteria in the blood of patients with severe AP. Therefore, this latter method in conjunction with DGGE is potentially an extremely useful tool in predicting septic morbidity and evaluating patients with the disease. Further research using increased numbers of patients, in particular those patients with necrosis and sepsis, is required to assess the reliability of PCR and DGGE in the rapid diagnosis of infection in AP.

  5. Analysis and Performance Evaluation of an All-Fiber Wide Range Interrogation System for a Bragg Grating Sensor Array

    OpenAIRE

    Rajan, Ginu; Semenova, Yuliya; Farrell, Gerald

    2009-01-01

    Analysis and performance evaluation of a macro-bend ¯ber based interrogation system for a Bragg grating sensor array is presented. Due to the characteristic properties of the macro-bend ¯ber ¯lter such as polarization and temperature dependence and the total noise associated with the ratiometric system, a best ¯t ratio slope is required to interrogate multiple FBGs whose peak wavelengths are spread over a wide wavelength range, rather than the optimal slope for individual FBG. In this paper f...

  6. Separation of Trivalent Actinides from Lanthanides Using a Capillary Electrophoresis

    International Nuclear Information System (INIS)

    A separation of 241Am(III) from 152,154Eu(III) was carried out using a capillary electrophoresis technique in a mixed solvent (CH3OH/H2O) system containing thiocyanate ion. First, the formation constants (βn) between thiocyanate ion and Eu(III) or Am(III) were investigated in the mixed solvent solutions by a back-extraction technique using bis (2-ethylhexyl) hydrogen phosphate-toluene. The mean charges calculated on the basis of the data of βn for Eu(III) were comparatively higher than those for Am(III). Based on the differences between the mean charges of Eu(III) and Am(III), separations for Am(III)/Eu(III) by means of capillary electrophoresis technique were tried in the (H+, Na+)(SCN-, ClO4-) mixed solvent solutions. It was proved that Am(III) was completely separated from Eu(III). (authors)

  7. Optimizing Chemical Sensor Array Sizes

    International Nuclear Information System (INIS)

    Optimal selection of array sensors for a chemical sensing application is a nontrivial task. It is commonly believed that ''more is better'' when choosing the number of sensors required to achieve good chemical selectivity. However, cost and system complexity issues point towards the choice of small arrays. A quantitative array optimization is carried out to explore the selectivity of arrays of partially-selective chemical sensors as a function of array size. It is shown that modest numbers (dozens) of target analytes are completely distinguished with a range of arrays sizes. However, the array selectivity and the robustness against sensor sensitivity variability are significantly degraded if the array size is increased above a certain number of sensors, so that relatively small arrays provide the best performance. The results also suggest that data analyses for very large arrays of partially-selective sensors will be optimized by separately anal yzing small sensor subsets

  8. Microfabricated capillary electrophoresis amino acid chirality analyzer for extraterrestrial exploration

    Science.gov (United States)

    Hutt, L. D.; Glavin, D. P.; Bada, J. L.; Mathies, R. A.

    1999-01-01

    Chiral separations of fluorescein isothiocyanate-labeled amino acids have been performed on a microfabricated capillary electrophoresis chip to explore the feasibility of using such devices to analyze for extinct or extant life signs in extraterrestrial environments. The test system consists of a folded electrophoresis channel (19.0 cm long x 150 microns wide x 20 microns deep) that was photolithographically fabricated in a 10-cm-diameter glass wafer sandwich, coupled to a laser-excited confocal fluorescence detection apparatus providing subattomole sensitivity. Using a sodium dodecyl sulfate/gamma-cyclodextrin pH 10.0 carbonate electrophoresis buffer and a separation voltage of 550 V/cm at 10 degrees C, baseline resolution was observed for Val, Ala, Glu, and Asp enantiomers and Gly in only 4 min. Enantiomeric ratios were determined for amino acids extracted from the Murchison meteorite, and these values closely matched values determined by HPLC. These results demonstrate the feasibility of using microfabricated lab-on-a-chip systems to analyze extraterrestrial samples for amino acids.

  9. Detecção eletroquímica em eletroforese capilar Electrochemical detection in capillary electrophoresis

    OpenAIRE

    José Alberto Fracassi da Silva

    2003-01-01

    This review focuses the development of electrochemical detection systems coupled to capillary electrophoresis. Conductometric, amperometric, voltametric, and potentiometric modes of detection are reviewed. The positioning of the electrodes, interferences of high electric field, and the materials employed in the fabrication and modification of the electrodes are discussed. The advantages of the use of electrochemical detection with capillary electrophoresis, regarding to the sensitivity and se...

  10. Techniques for heating eccentrically located tumors with the BSD annular phased array system (APAS): Clinical experience

    International Nuclear Information System (INIS)

    The authors are currently investigating the potential for treatment optimization with the BSD APAS in tumors which are eccentrically located within the lower abdomen and pelvis. Attempts have been made to manipulate electric field (E-field) distribution during treatments through frequency changes and partial array activation (driving less than all four quadrants). Field shifts are qualitatively documented using the manufacturer's supplied diode array probes located at the patient/bolus interface in anterior, posterior and bilateral positions. Preliminary findings indicate that the internal E-field distributions can be manipulated to result in better treatment tolerance and better temperature distributions in selected target volumes. Phantom and clinical data are presented demonstrating the utility of these approaches

  11. Energy-efficient population coding constrains network size of a neuronal array system

    Science.gov (United States)

    Yu, Lianchun; Zhang, Chi; Liu, Liwei; Yu, Yuguo

    2016-01-01

    We consider the open issue of how the energy efficiency of the neural information transmission process, in a general neuronal array, constrains the network size, and how well this network size ensures the reliable transmission of neural information in a noisy environment. By direct mathematical analysis, we have obtained general solutions proving that there exists an optimal number of neurons in the network, where the average coding energy cost (defined as energy consumption divided by mutual information) per neuron passes through a global minimum for both subthreshold and superthreshold signals. With increases in background noise intensity, the optimal neuronal number decreases for subthreshold signals and increases for suprathreshold signals. The existence of an optimal number of neurons in an array network reveals a general rule for population coding that states that the neuronal number should be large enough to ensure reliable information transmission that is robust to the noisy environment but small enough to minimize energy cost.

  12. Contact charge electrophoresis: experiment and theory.

    Science.gov (United States)

    Drews, Aaron M; Cartier, Charles A; Bishop, Kyle J M

    2015-04-01

    Contact charge electrophoresis (CCEP) uses steady electric fields to drive the continuous, oscillatory motion of conductive particles and droplets between two or more electrodes. These rapid oscillations can be rectified to direct the motion of objects within microfluidic environments using low-power, dc voltage. Here, we compare high precision experimental measurements of CCEP within a microfluidic system to equally detailed theoretical predictions on the motion of a conductive particle between parallel electrodes. We use a simple, capillary microfluidic platform that combines high-speed imaging with precision electrical measurements to enable the synchronized acquisition of both the particle location and the electric current due to particle motion. The experimental results are compared to those of a theoretical model, which relies on a Stokesian dynamics approach to accurately describe both the electrostatic and hydrodynamic problems governing particle motion. We find remarkable agreement between theory and experiment, suggesting that particle motion can be accurately captured by a combination of classical electrostatics and low-Reynolds number hydrodynamics. Building on this agreement, we offer new insight into the charge transfer process that occurs when the particle nears contact with an electrode surface. In particular, we find that the particle does not make mechanical contact with the electrode but rather that charge transfer occurs at finite surface separations of >0.1 μm by means of an electric discharge through a thin lubricating film. We discuss the implications of these findings on the charging of the particle and its subsequent dynamics. PMID:25785396

  13. Differentiation of enantiomers by capillary electrophoresis.

    Science.gov (United States)

    Scriba, Gerhard K E

    2013-01-01

    Capillary electrophoresis (CE) has matured to one of the major liquid phase enantiodifferentiation techniques since the first report in 1985. This can be primarily attributed to the flexibility as well as the various modes available including electrokinetic chromatography (EKC), micellar electrokinetic chromatography (MEKC), and microemulsion electrokinetic chromatography (MEEKC). In contrast to chromatographic techniques, the chiral selector is mobile in the background electrolyte. Furthermore, a large variety of chiral selectors are available that can be easily combined in the same separation system. In addition, the migration order of the enantiomers can be adjusted by a number of approaches. In CE enantiodifferentiations the separation principle is comparable to chromatography while the principle of the movement of the analytes in the capillary is based on electrophoretic phenomena. The present chapter will focus on mechanistic aspects of CE enantioseparations including enantiomer migration order and the current understanding of selector-selectand structures. Selected examples of the basic enantioseparation modes EKC, MEKC, and MEEKC will be discussed. PMID:23666080

  14. Dynamic Experiment Design Regularization Approach to Adaptive Imaging with Array Radar/SAR Sensor Systems

    OpenAIRE

    Stewart Santos; José Tuxpan; Yuriy Shkvarko

    2011-01-01

    We consider a problem of high-resolution array radar/SAR imaging formalized in terms of a nonlinear ill-posed inverse problem of nonparametric estimation of the power spatial spectrum pattern (SSP) of the random wavefield scattered from a remotely sensed scene observed through a kernel signal formation operator and contaminated with random Gaussian noise. First, the Sobolev-type solution space is constructed to specify the class of consistent kernel SSP estimators with the reproducing kernel ...

  15. Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

    OpenAIRE

    Larraneta Landa, Eneko; Lutton, Rebecca E.M.; Woolfson, A. David; Ryan F Donnelly

    2016-01-01

    Transdermal drug delivery offers a number of advantages for the patient, due not only its non-invasive and convenient nature, but also factors such as avoidance of first pass metabolism and prevention of gastrointestinal degradation. It has been demonstrated that microneedle arrays can increase the number of compounds amenable to transdermal delivery by penetrating the skin's protective barrier, the stratum corneum, and creating a pathway for drug permeation to the dermal tissue below. Micron...

  16. Advanced integrated optical beam forming networks for broadband phased array antenna systems

    OpenAIRE

    Burla, Maurizio

    2013-01-01

    Since the first half of the twentieth century, a large interest has been addressed by the scientific and engineering community to the world of phased arrays antennas. Their technology started to be developed during the Second World War for early warning radar techniques to identify threats from the skies. Those capable antennas have been deployed over the years in a number of diversified fields to address different applications needs. First employed almost exclusively in the defense and space...

  17. Coupling and tuning of modal frequencies in direct current biased microelectromechanical systems arrays

    Energy Technology Data Exchange (ETDEWEB)

    Kambali, Prashant N.; Swain, Gyanadutta; Pandey, Ashok Kumar, E-mail: ashok@iith.ac.in [Department of Mechanical and Aerospace Engineering, IIT Hyderabad, Yeddumailaram 502205 (India); Buks, Eyal [Faculty of Electrical Engineering, Technion-Israel Institute of Technology, Haifa 32000 (Israel); Gottlieb, Oded [Faculty of Mechanical Engineering, Technion-Israel Institute of Technology, Haifa 32000 (Israel)

    2015-08-10

    Understanding the coupling of different modal frequencies and their tuning mechanisms has become essential to design multi-frequency MEMS devices. In this work, we fabricate a MEMS beam with fixed boundaries separated from two side electrodes and a bottom electrode. Subsequently, we perform experiments to obtain the frequency variation of in-plane and out-of-plane mechanical modes of the microbeam with respect to both DC bias and laser heating. We show that the frequencies of the two modes coincide at a certain DC bias, which in turn can also be varied due to temperature. Subsequently, we develop a theoretical model to predict the variation of the two modes and their coupling due to a variable gap between the microbeam and electrodes, initial tension, and fringing field coefficients. Finally, we discuss the influence of frequency tuning parameters in arrays of 3, 33, and 40 microbeams, respectively. It is also found that the frequency bandwidth of a microbeam array can be increased to as high as 25 kHz for a 40 microbeam array with a DC bias of 80 V.

  18. P25 nanoparticles decorated on titania nanotubes arrays as effective drug delivery system for ibuprofen

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhang; Xie, Chunlin; Luo, Fei; Li, Ping; Xiao, Xiufeng, E-mail: xfxiao@fjnu.edu.cn

    2015-01-01

    Highlights: • P25 nanoparticles decorated on titania nanotube arrays were prepared by hydrothermal treatment. • P25 nanoparticles were conducive to improve the loading effect of ibuprofen into nanotube arrays. • The diameters of the decorated nanotubes were decrease markedly which led to an effective and prolonged drug release. - Abstract: In this study, uniformly distributed layer of P25 nanoparticles (NPs) decorated on titania (TiO{sub 2}) nanotubes (TNTs) arrays was prepared in a teflon-lined stainless steel autoclave by the hydrothermal treatment. To investigate the influence of the P25 concentration, different concentrations of P25 NPs were added into the solution to obtain the optimal decorative effect. TNTs decorated with P25 (TNTs–P25) and TNTs without P25 decorated on its surface were loaded with ibuprofen (IBU) via vacuum drying and its release properties were investigated. The samples were characterized by field emission scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy. The results indicated that P25 NPs were successfully decorated on the surface of TNTs by hydrothermal method and the optimal concentration was found to be 7.5 × 10{sup −4} M. P25 NPs decorated on TNTs led to a significant increase in the specific surface area of TNTs which was conducive to improve the loading effect of IBU. Importantly, the diameters of the decorated nanotubes were reduced to 100 ± 10 nm and the increase in roughness led to an effective and prolonged drug release.

  19. Coupling and tuning of modal frequencies in direct current biased microelectromechanical systems arrays

    International Nuclear Information System (INIS)

    Understanding the coupling of different modal frequencies and their tuning mechanisms has become essential to design multi-frequency MEMS devices. In this work, we fabricate a MEMS beam with fixed boundaries separated from two side electrodes and a bottom electrode. Subsequently, we perform experiments to obtain the frequency variation of in-plane and out-of-plane mechanical modes of the microbeam with respect to both DC bias and laser heating. We show that the frequencies of the two modes coincide at a certain DC bias, which in turn can also be varied due to temperature. Subsequently, we develop a theoretical model to predict the variation of the two modes and their coupling due to a variable gap between the microbeam and electrodes, initial tension, and fringing field coefficients. Finally, we discuss the influence of frequency tuning parameters in arrays of 3, 33, and 40 microbeams, respectively. It is also found that the frequency bandwidth of a microbeam array can be increased to as high as 25 kHz for a 40 microbeam array with a DC bias of 80 V

  20. [Development of online conventional array-based two-dimensional liquid chromatographic system for proteins separation in human plasma].

    Science.gov (United States)

    Huang, Zhi; Hong, Guangfeng; Gao, Mingxia; Zhang, Xiangmin

    2014-04-01

    Human plasma is one of the proteins-containing samples most difficult to characterize on account of the wide dynamic concentration range of its intact proteins. Herein, we developed a high-throughput conventional array-based two-dimensional liquid chromatographic system for proteins separation in human plasma in online mode. In the system, a conventional strong-anion exchange chromatographic column was used as the first separation dimension and eight parallel conventional reversed-phase liquid chromatographic columns were integrated as the second separation dimension. The fractions from the first dimension were sequentially transferred into the corresponding reversed-phase liquid chromatographic precolumns for retention and enrichment using a 10-port electrically actuated multi-position valve. The second dimensional solvent flow was directly and identically split into 8 channels. The fractions were concurrently back-flushed from the precolumns into the 8 conventional RP columns and were separated simultaneously. An 8-channel fraction collector was refitted to collect the reversed-phase liquid chromatographic fractions for further investigation. Bicinchoninic acid (BCA) dyein solution was conveniently used for high-abundance protein location. Two separation dimensions were relatively independent parts, as well as each channel of the second dimensional array separation. Therefore, the new system could improve the separation throughput and total peak capacity. The system was successfully applied for the separation of human plasma intact proteins. The results indicated the established system is an effective method for removing high abundance proteins in plasma and in-depth research in plasma proteomics. PMID:25069321

  1. Solid-State Multi-Sensor Array System for Real Time Imaging of Magnetic Fields and Ferrous Objects

    Science.gov (United States)

    Benitez, D.; Gaydecki, P.; Quek, S.; Torres, V.

    2008-02-01

    In this paper the development of a solid-state sensors based system for real-time imaging of magnetic fields and ferrous objects is described. The system comprises 1089 magneto inductive solid state sensors arranged in a 2D array matrix of 33×33 files and columns, equally spaced in order to cover an approximate area of 300 by 300 mm. The sensor array is located within a large current-carrying coil. Data is sampled from the sensors by several DSP controlling units and finally streamed to a host computer via a USB 2.0 interface and the image generated and displayed at a rate of 20 frames per minute. The development of the instrumentation has been complemented by extensive numerical modeling of field distribution patterns using boundary element methods. The system was originally intended for deployment in the non-destructive evaluation (NDE) of reinforced concrete. Nevertheless, the system is not only capable of producing real-time, live video images of the metal target embedded within any opaque medium, it also allows the real-time visualization and determination of the magnetic field distribution emitted by either permanent magnets or geometries carrying current. Although this system was initially developed for the NDE arena, it could also have many potential applications in many other fields, including medicine, security, manufacturing, quality assurance and design involving magnetic fields.

  2. Combining the switched-beam and beam-steering capabilities in a 2-D phased array antenna system

    Science.gov (United States)

    Tsai, Yi-Che; Chen, Yin-Bing; Hwang, Ruey-Bing

    2016-01-01

    This paper presents the development, fabrication, and measurement of a novel beam-forming system consisting of 16 subarray antennas, each containing four aperture-coupled patch antennas, and the application of this system in smart wireless communication systems. The beam patterns of each of the subarray antennas can be switched toward one of nine zones over a half space by adjusting the specific phase delay angles among the four antenna elements. Furthermore, when all subarrays are pointed at the same zone, slightly continuous beam steering in around 1° increments can be achieved by dynamically altering the progressive phase delay angle among the subarrays. Phase angle calibration was implemented by coupling each transmitter output and down converter into the in-phase/quadrature baseband to calculate the correction factor to the weight. In addition, to validate the proposed concepts and the fabricated 2-D phased array antenna system, this study measured the far-field radiation patterns of the aperture-coupled patch array integrated with feeding networks and a phase-calibration system to carefully verify its spatially switched-beam and beam-steering characteristics at a center frequency of 2.4 GHz which can cover the industrial, scientific, and medical band and some long-term evolution applications. In addition, measured results were compared with calculated results, and agreement between them was observed.

  3. Commissioning of a 3D pretreatment quality-assurance system in volumetric techniques based in 2D detector arrays

    International Nuclear Information System (INIS)

    The present experience about intensity-modulated radiation therapy pre-treatment QA points to a paradigm shift oriented to metrics based in clinically relevant parameters. This work shows the commissioning of a QA system used in the verification of volumetric treatments based in 2D ion chamber arrays. This system accomplishes with the initial hypothesis making the dose calculation and reconstruction in actual patient anatomy possible from measurements taken during the verification process. Beam reference parameters are compared with those obtained with the system: absolute dose, output factors and relative dose distributions. Simple test cases are evaluated comparing dose-volume parameters and ion chamber-based measurements. Finally the system is applied to the verification of 12 actual clinical test cases, comparing ion chamber measurements, usual planar dose distributions analysis, dose-volume parameters from each anatomic site and 3D gamma tests. Results make the potential advantage of these systems clear compared with those based in traditional metrics. (Author)

  4. Gimbals Drive and Control Electronics Design, Development and Testing of the LRO High Gain Antenna and Solar Array Systems

    Science.gov (United States)

    Chernyakov, Boris; Thakore, Kamal

    2010-01-01

    Launched June 18, 2009 on an Atlas V rocket, NASA's Lunar Reconnaissance Orbiter (LRO) is the first step in NASA's Vision for Space Exploration program and for a human return to the Moon. The spacecraft (SC) carries a wide variety of scientific instruments and provides an extraordinary opportunity to study the lunar landscape at resolutions and over time scales never achieved before. The spacecraft systems are designed to enable achievement of LRO's mission requirements. To that end, LRO's mechanical system employed two two-axis gimbal assemblies used to drive the deployment and articulation of the Solar Array System (SAS) and the High Gain Antenna System (HGAS). This paper describes the design, development, integration, and testing of Gimbal Control Electronics (GCE) and Actuators for both the HGAS and SAS systems, as well as flight testing during the on-orbit commissioning phase and lessons learned.

  5. All-Optical Modulation of Localized Surface Plasmon Coupling in a Hybrid System Composed of Photo-Switchable Gratings and Au Nanodisk Arrays

    OpenAIRE

    Liu, Yan Jun; Zheng, Yue Bing; Liou, Justin; Chiang, I-Kao; Khoo, Iam Choon; Huang, Tony Jun

    2011-01-01

    We conduct a real-time study of all-optical modulation of localized surface plasmon resonance (LSPR) coupling in a hybrid system that integrates a photo-switchable optical grating with a gold nanodisk array. This hybrid system enables us to investigate two important interactions: 1) LSPR-enhanced grating diffraction, and 2) diffraction-mediated LSPR in the Au nanodisk array. The physical mechanism underlying these interactions was analyzed and experimentally confirmed. With its advantages in ...

  6. Development of an Ultrasonic Phased Array System for Wellbore Integrity Evaluation and Near-Wellbore Fracture Network Mapping of Injection and Production Wells in Geothermal Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Almansouri, Hani [Purdue University; Foster, Benjamin [Purdue University; Kisner, Roger A [ORNL; Polsky, Yarom [ORNL; Bouman, Charlie [Purdue University

    2016-01-01

    This paper documents our progress developing an ultrasound phased array system in combination with a model-based iterative reconstruction (MBIR) algorithm to inspect the health of and characterize the composition of the near-wellbore region for geothermal reservoirs. The main goal for this system is to provide a near-wellbore in-situ characterization capability that will significantly improve wellbore integrity evaluation and near well-bore fracture network mapping. A more detailed image of the fracture network near the wellbore in particular will enable the selection of optimal locations for stimulation along the wellbore, provide critical data that can be used to improve stimulation design, and provide a means for measuring evolution of the fracture network to support long term management of reservoir operations. Development of such a measurement capability supports current hydrothermal operations as well as the successful demonstration of Engineered Geothermal Systems (EGS). The paper will include the design of the phased array system, the performance specifications, and characterization methodology. In addition, we will describe the MBIR forward model derived for the phased array system and the propagation of compressional waves through a pseudo-homogenous medium.

  7. An Automated Sensing System for Steel Bridge Inspection Using GMR Sensor Array and Magnetic Wheels of Climbing Robot

    Directory of Open Access Journals (Sweden)

    Rui Wang

    2016-01-01

    Full Text Available Corrosion is one of the main causes of deterioration of steel bridges. It may cause metal loss and fatigue cracks in the steel components, which would lead to the collapse of steel bridges. This paper presents an automated sensing system to detect corrosion, crack, and other kinds of defects using a GMR (Giant Magnetoresistance sensor array. Defects will change the relative permeability and electrical conductivity of the material. As a result, magnetic field density generated by ferromagnetic material and the magnetic wheels will be changed. The defects are able to be detected by using GMR sensor array to measure the changes of magnetic flux density. In this study, magnetic wheels are used not only as the adhesion device of the robot, but also as an excitation source to provide the exciting magnetic field for the sensing system. Furthermore, compared to the eddy current method and the MFL (magnetic flux leakage method, this sensing system suppresses the noise from lift-off value fluctuation by measuring the vertical component of induced magnetic field that is perpendicular to the surface of the specimen in the corrosion inspection. Simulations and experimental results validated the feasibility of the system for the automated defect inspection.

  8. A Wireless Electronic Nose System Using a Fe2O3 Gas Sensing Array and Least Squares Support Vector Regression

    Directory of Open Access Journals (Sweden)

    Yingguo Cheng

    2011-01-01

    Full Text Available This paper describes the design and implementation of a wireless electronic nose (WEN system which can online detect the combustible gases methane and hydrogen (CH4/H2 and estimate their concentrations, either singly or in mixtures. The system is composed of two wireless sensor nodes—a slave node and a master node. The former comprises a Fe2O3 gas sensing array for the combustible gas detection, a digital signal processor (DSP system for real-time sampling and processing the sensor array data and a wireless transceiver unit (WTU by which the detection results can be transmitted to the master node connected with a computer. A type of Fe2O3 gas sensor insensitive to humidity is developed for resistance to environmental influences. A threshold-based least square support vector regression (LS-SVR estimator is implemented on a DSP for classification and concentration measurements. Experimental results confirm that LS-SVR produces higher accuracy compared with artificial neural networks (ANNs and a faster convergence rate than the standard support vector regression (SVR. The designed WEN system effectively achieves gas mixture analysis in a real-time process.

  9. Microcavity arrays as an in vitro model system of the bone marrow niche for hematopoietic stem cells.

    Science.gov (United States)

    Wuchter, Patrick; Saffrich, Rainer; Giselbrecht, Stefan; Nies, Cordula; Lorig, Hanna; Kolb, Stephanie; Ho, Anthony D; Gottwald, Eric

    2016-06-01

    In previous studies human mesenchymal stromal cells (MSCs) maintained the "stemness" of human hematopoietic progenitor cells (HPCs) through direct cell-cell contact in two-dimensional co-culture systems. We establish a three-dimensional (3D) co-culture system based on a custom-made chip, the 3(D)-KITChip, as an in vitro model system of the human hematopoietic stem cell niche. This array of up to 625 microcavities, with 300 μm size in each orientation, was inserted into a microfluidic bioreactor. The microcavities of the 3(D)-KITChip were inoculated with human bone marrow MSCs together with umbilical cord blood HPCs. MSCs used the microcavities as a scaffold to build a complex 3D mesh. HPCs were distributed three-dimensionally inside this MSC network and formed ß-catenin- and N-cadherin-based intercellular junctions to the surrounding MSCs. Using RT(2)-PCR and western blots, we demonstrate that a proportion of HPCs maintained the expression of CD34 throughout a culture period of 14 days. In colony-forming unit assays, the hematopoietic stem cell plasticity remained similar after 14 days of bioreactor co-culture, whereas monolayer co-cultures showed increasing signs of HPC differentiation and loss of stemness. These data support the notion that the 3D microenvironment created within the microcavity array preserves vital stem cell functions of HPCs more efficiently than conventional co-culture systems. PMID:26829941

  10. High-Throughput Genetic Analysis and Combinatorial Chiral Separations Based on Capillary Electrophoresis

    Energy Technology Data Exchange (ETDEWEB)

    Wenwan Zhong

    2003-08-05

    Capillary electrophoresis (CE) offers many advantages over conventional analytical methods, such as speed, simplicity, high resolution, low cost, and small sample consumption, especially for the separation of enantiomers. However, chiral method developments still can be time consuming and tedious. They designed a comprehensive enantioseparation protocol employing neutral and sulfated cyclodextrins as chiral selectors for common basic, neutral, and acidic compounds with a 96-capillary array system. By using only four judiciously chosen separation buffers, successful enantioseparations were achieved for 49 out of 54 test compounds spanning a large variety of pKs and structures. Therefore, unknown compounds can be screened in this manner to identify optimal enantioselective conditions in just one rn. In addition to superior separation efficiency for small molecules, CE is also the most powerful technique for DNA separations. Using the same multiplexed capillary system with UV absorption detection, the sequence of a short DNA template can be acquired without any dye-labels. Two internal standards were utilized to adjust the migration time variations among capillaries, so that the four electropherograms for the A, T, C, G Sanger reactions can be aligned and base calling can be completed with a high level of confidence. the CE separation of DNA can be applied to study differential gene expression as well. Combined with pattern recognition techniques, small variations among electropherograms obtained by the separation of cDNA fragments produced from the total RNA samples of different human tissues can be revealed. These variations reflect the differences in total RNA expression among tissues. Thus, this Ce-based approach can serve as an alternative to the DNA array techniques in gene expression analysis.

  11. Introduction to adaptive arrays

    CERN Document Server

    Monzingo, Bob; Haupt, Randy

    2011-01-01

    This second edition is an extensive modernization of the bestselling introduction to the subject of adaptive array sensor systems. With the number of applications of adaptive array sensor systems growing each year, this look at the principles and fundamental techniques that are critical to these systems is more important than ever before. Introduction to Adaptive Arrays, 2nd Edition is organized as a tutorial, taking the reader by the hand and leading them through the maze of jargon that often surrounds this highly technical subject. It is easy to read and easy to follow as fundamental concept

  12. The atmospheric transparency measured with a LIDAR system at the Telescope Array experiment

    CERN Document Server

    Tomida, Takayuki; Arai, Takahito; Benno, Takuya; Chikawa, Michiyuki; Doura, Koji; Fukushima, Masaki; Hiyama, Kazunori; Honda, Ken; Ikeda, Daisuke; Matthews, John N; Nakamura, Toru; Oku, Daisuke; Sagawa, Hiroyuki; Tokuno, Hisao; Tameda, Yuichiro; Thomson, Gordon B; Tsunesada, Yoshiki; Udo, Shigeharu; Ukai, Hisashi; 10.1016/j.nima.2011.07.012

    2011-01-01

    An atmospheric transparency was measured using a LIDAR with a pulsed UV laser (355nm) at the observation site of Telescope Array in Utah, USA. The measurement at night for two years in $2007\\sim 2009$ revealed that the extinction coefficient by aerosol at the ground level is $0.033^{+0.016}_{-0.012} \\rm km^{-1}$ and the vertical aerosol optical depth at 5km above the ground is $0.035^{+0.019}_{-0.013}$. A model of the altitudinal aerosol distribution was built based on these measurements for the analysis of atmospheric attenuation of the fluorescence light generated by ultra high energy cosmic rays.

  13. The atmospheric transparency measured with a LIDAR system at the Telescope Array experiment

    International Nuclear Information System (INIS)

    An atmospheric transparency was measured using a LIDAR with a pulsed UV laser (355 nm) at the observation site of Telescope Array in Utah, USA. The measurement at night for two years in 2007-2009 revealed that the extinction coefficient by aerosol at the ground level is 0.033-0.012+0.016km-1 and the vertical aerosol optical depth at 5 km above the ground is 0.035-0.013+0.019. A model of the altitudinal aerosol distribution was built based on these measurements for the analysis of atmospheric attenuation of the fluorescence light generated by ultra high energy cosmic rays.

  14. Frequency sweep for a beam system with local unilateral contact modeling satellite solar arrays

    CERN Document Server

    Hazim, Hamad

    2009-01-01

    In order to save mass of satellite solar arrays, the flexibility of the panels becomes not negligible and they may strike each other; this may damage the structure. To prevent this, rubber snubbers are mounted at well chosen points of the structure and they act as one sided linear spring; as a negative consequence, the dynamic of these panels becomes nonlinear. The finite element approximation is used to solve partial differential equations governing the structural dynamic. Frequency sweep has been performed numerically to study the dynamic behavior. Non linear normal modes are under study

  15. Numerical and Experimental Study for a Beam System with Local Unilateral Contact Modeling Satellite Solar Arrays

    CERN Document Server

    Hazim, Hamad; Ferguson, Neil

    2009-01-01

    The mass reduction of satellite solar arrays results in significant panel flexibility, so possibly striking one another dynamically leading ultimately to structural damage. To prevent this, rubber snubbers are mounted at well chosen points of the structure and they act as one sided linear spring; as a negative consequence, the dynamic of these panels becomes nonlinear. The finite element approximation is used to solve partial differential equations governing the structural dynamic. The models are validated and adjusted with experiments done in the ISVR laboratory, Southampton university.

  16. Application of Global Dynamic Reconfiguration in Artificial Neural Network System based on Field Programmable Gate Array

    Institute of Scientific and Technical Information of China (English)

    LI Wei; WANG Wei; MA Yi-mei; WANG Jin-hai

    2008-01-01

    Presented is a global dynamic reconfiguration design of an artificial neural network based on field programmable gate array(FPGA). Discussed are the dynamic reconfiguration principles and methods. Proposed is a global dynamic reconfiguration scheme using Xilinx FPGA and platform flash. Using the revision capabilities of Xilinx XCF32P platform flash, an artificial neural network based on Xilinx XC2V30P Virtex-Ⅱ can be reconfigured dynamically from back propagation(BP) learning algorithms to BP network testing algorithms. The experimental results indicate that the scheme is feasible, and that, using dynamic reconfiguration technology, FPGA resource utilization can be reduced remarkably.

  17. Preparative electrophoresis of industrial fission product solutions

    International Nuclear Information System (INIS)

    The aim of this work is to contribute to the development of the continuous electrophoresis technique while studying its application in the preparative electrophoresis of industrial fission product solutions. The apparatus described is original. It was built for the purposes of the investigation and proved very reliable in operation. The experimental conditions necessary to maintain and supervise the apparatus in a state of equilibrium are examined in detail; their stability is an important factor, indispensable to the correct performance of an experiment. By subjecting an industrial solution of fission products to preparative electrophoresis it is possible, according to the experimental conditions, to prepare carrier-free radioelements of radiochemical purity (from 5 to 7 radioelements): 137Cs, 90Sr, 141+144Ce, 91Y, 95Nb, 95Zr, 103+106Ru. (author)

  18. Fiber-optic liquid level monitoring system using microstructured polymer fiber Bragg grating array sensors: performance analysis

    DEFF Research Database (Denmark)

    Marques, C. A. F.; Pospori, A.; Saez-Rodriguez, D.;

    2015-01-01

    A highly sensitive liquid level monitoring system based on microstructured polymer optical fiber Bragg grating (mPOFBG) array sensors is reported for the first time. The configuration is based on five mPOFBGs inscribed in the same fiber in the 850 nm spectral region, showing the potential...... to interrogate liquid level by measuring the strain induced in each mPOFBG embedded in a silicone rubber (SR) diaphragm, which deforms due to hydrostatic pressure variations. The sensor exhibits a highly linear response over the sensing range, a good repeatability, and a high resolution. The sensitivity...... of temperature and the liquid density....

  19. Multichannel arrays on polymer substrates: toward a disposable proteomics chip

    Science.gov (United States)

    Becker, Holger; Ehrfeld, Wolfgang; Pommersheim, Rainer

    1999-03-01

    Miniaturization is dramatically changing the shape of biotechnology. After the first wave of discoveries inventions in the field of analytical methods and DNA-probes on silicon chips, the trend in recent years has been to more complex and integrated systems in terms of microfabrication for production purposes mainly focused on polymer substrates. Additionally, an increased complexity in the biochemical functionality for tasks like cell handling, cell lysis, polymerase chain reaction, DNA-sequencing and recently in the field of proteomics research can be observed. In this paper we describe the practical approach to a polymer substrate based, microfabricated chip-based multichannel array for 2D capillary electrophoresis. This chip can be fabricated by classical mass production techniques like hot embossing or injection modeling, and has the potential for on-chip-integration of electrodes and detection system.

  20. Microfabricated ion trap array

    Science.gov (United States)

    Blain, Matthew G.; Fleming, James G.

    2006-12-26

    A microfabricated ion trap array, comprising a plurality of ion traps having an inner radius of order one micron, can be fabricated using surface micromachining techniques and materials known to the integrated circuits manufacturing and microelectromechanical systems industries. Micromachining methods enable batch fabrication, reduced manufacturing costs, dimensional and positional precision, and monolithic integration of massive arrays of ion traps with microscale ion generation and detection devices. Massive arraying enables the microscale ion traps to retain the resolution, sensitivity, and mass range advantages necessary for high chemical selectivity. The reduced electrode voltage enables integration of the microfabricated ion trap array with on-chip circuit-based rf operation and detection electronics (i.e., cell phone electronics). Therefore, the full performance advantages of the microfabricated ion trap array can be realized in truly field portable, handheld microanalysis systems.

  1. Synchronization sampling method based on delta-sigma analog-digital converter for underwater towed array system.

    Science.gov (United States)

    Jiang, Jia-Jia; Duan, Fa-Jie; Li, Yan-Chao; Hua, Xiang-Ning

    2014-03-01

    Synchronization sampling is very important in underwater towed array system where every acquisition node (AN) samples analog signals by its own analog-digital converter (ADC). In this paper, a simple and effective synchronization sampling method is proposed to ensure synchronized operation among different ANs of the underwater towed array system. We first present a master-slave synchronization sampling model, and then design a high accuracy phase-locked loop to synchronize all delta-sigma ADCs to a reference clock. However, when the master-slave synchronization sampling model is used, both the time-delay (TD) of messages traveling along the wired transmission medium and the jitter of the clocks will bring out synchronization sampling error (SSE). Therefore, a simple method is proposed to estimate and compensate the TD of the messages transmission, and then another effective method is presented to overcome the SSE caused by the jitter of the clocks. An experimental system with three ANs is set up, and the related experimental results verify the validity of the synchronization sampling method proposed in this paper. PMID:24689606

  2. Undergraduate physics laboratory: Electrophoresis in chromatography paper

    Science.gov (United States)

    Hyde, Alexander; Batishchev, Oleg

    2015-12-01

    An experiment studying the physical principles of electrophoresis in liquids was developed for an undergraduate laboratory. We have improved upon the standard agarose gel electrophoresis experimental regime with a straightforward and cost-effective procedure, in which drops of widely available black food coloring were separated by electric field into their dye components on strips of chromatography paper soaked in a baking soda/water solution. Terminal velocities of seven student-safe dyes were measured as a function of the electric potential applied along the strips. The molecular mobility was introduced and calculated by analyzing data for a single dye. Sources of systematic and random errors were investigated.

  3. Multilocus enzyme electrophoresis study of Bacillus sphaericus

    Directory of Open Access Journals (Sweden)

    Viviane Zahner

    1995-02-01

    Full Text Available Multilocus enzyme electrophoresis (MLEE has been used in the study of some Bacillus species. In this work we applied MLEE and numerical analysis in the study of the Bacillus sphaericus group. B. sphaericus can be distinguished from other entomopathogenic Bacillus by a unique allele (NP-4. Within the species, all insect pathogens were recovered in the same phenetic cluster and all of these strains have the same band position (electrophoresis migration on the agarose gel (ADH-2. The entomopathogenic group of B. sphaericus seems to be a clonal population, having two widespread frequent genotypes (zymovar 59 and zymovar 119.

  4. Microfluidic chip-capillary electrophoresis devices

    CERN Document Server

    Fung, Ying Sing; Du, Fuying; Guo, Wenpeng; Ma, Tongmei; Nie, Zhou; Sun, Hui; Wu, Ruige; Zhao, Wenfeng

    2015-01-01

    Capillary electrophoresis (CE) and microfluidic chip (MC) devices are relatively mature technologies, but this book demonstrates how they can be integrated into a single, revolutionary device that can provide on-site analysis of samples when laboratory services are unavailable. By introducing the combination of CE and MC technology, Microfluidic Chip-Capillary Electrophoresis Devices broadens the scope of chemical analysis, particularly in the biomedical, food, and environmental sciences.The book gives an overview of the development of MC and CE technology as well as technology that now allows

  5. Dynamic experiment design regularization approach to adaptive imaging with array radar/SAR sensor systems.

    Science.gov (United States)

    Shkvarko, Yuriy; Tuxpan, José; Santos, Stewart

    2011-01-01

    We consider a problem of high-resolution array radar/SAR imaging formalized in terms of a nonlinear ill-posed inverse problem of nonparametric estimation of the power spatial spectrum pattern (SSP) of the random wavefield scattered from a remotely sensed scene observed through a kernel signal formation operator and contaminated with random Gaussian noise. First, the Sobolev-type solution space is constructed to specify the class of consistent kernel SSP estimators with the reproducing kernel structures adapted to the metrics in such the solution space. Next, the "model-free" variational analysis (VA)-based image enhancement approach and the "model-based" descriptive experiment design (DEED) regularization paradigm are unified into a new dynamic experiment design (DYED) regularization framework. Application of the proposed DYED framework to the adaptive array radar/SAR imaging problem leads to a class of two-level (DEED-VA) regularized SSP reconstruction techniques that aggregate the kernel adaptive anisotropic windowing with the projections onto convex sets to enforce the consistency and robustness of the overall iterative SSP estimators. We also show how the proposed DYED regularization method may be considered as a generalization of the MVDR, APES and other high-resolution nonparametric adaptive radar sensing techniques. A family of the DYED-related algorithms is constructed and their effectiveness is finally illustrated via numerical simulations. PMID:22163859

  6. Dynamic Experiment Design Regularization Approach to Adaptive Imaging with Array Radar/SAR Sensor Systems

    Directory of Open Access Journals (Sweden)

    Stewart Santos

    2011-04-01

    Full Text Available We consider a problem of high-resolution array radar/SAR imaging formalized in terms of a nonlinear ill-posed inverse problem of nonparametric estimation of the power spatial spectrum pattern (SSP of the random wavefield scattered from a remotely sensed scene observed through a kernel signal formation operator and contaminated with random Gaussian noise. First, the Sobolev-type solution space is constructed to specify the class of consistent kernel SSP estimators with the reproducing kernel structures adapted to the metrics in such the solution space. Next, the “model-free” variational analysis (VA-based image enhancement approach and the “model-based” descriptive experiment design (DEED regularization paradigm are unified into a new dynamic experiment design (DYED regularization framework. Application of the proposed DYED framework to the adaptive array radar/SAR imaging problem leads to a class of two-level (DEED-VA regularized SSP reconstruction techniques that aggregate the kernel adaptive anisotropic windowing with the projections onto convex sets to enforce the consistency and robustness of the overall iterative SSP estimators. We also show how the proposed DYED regularization method may be considered as a generalization of the MVDR, APES and other high-resolution nonparametric adaptive radar sensing techniques. A family of the DYED-related algorithms is constructed and their effectiveness is finally illustrated via numerical simulations.

  7. A flexible touch-pressure sensor array with wireless transmission system for robotic skin

    Science.gov (United States)

    Huang, Ying; Fang, Ding; Wu, Can; Wang, Weihua; Guo, Xiaohui; Liu, Ping

    2016-06-01

    Human skin contains multiple receptors and is able to sense various stimuli such as temperature, touch, pressure, and deformation, with high sensitivity and resolution. The development of skin-like sensors capable of sensing these stimuli is of great importance for various applications such as robots, touch detection, temperature monitoring, and strain gauges. Great efforts have been made to develop high performance touch sensor and pressure sensor. Compared with general sensor, the touch-pressure sensor which is reported in this paper not only can measure large pressure but also has a high resolution in the small range so that it can feel slight touch. The sensor has a vertical structure. The upper layer is made of silicone rubber as the capacitive layer and the lower layer employs multiwall carbon nanotubes and carbon black filled silicone rubber as the resistive layer. The electrodes are made by conductive silver adhesives. In addition, the electrodes are connected to the pads on the top surface of the flexible printed circuit board by enamelled wires which made it easier to fabricate sensor array. The resolution of the touch-pressure sensor in the range of 0-10 N and 10-100 N are 0.1 N and 1 N, respectively. The experimental data of the sensor are sent by ZigBee wireless technology which reduces the complexity of the wiring and provides a convenient way to apply and maintain the sensor array.

  8. High-precision Measurements of Ionospheric TEC Gradients with the Very Large Array VHF System

    CERN Document Server

    Helmboldt, J F; Intema, H T; Dymond, K F

    2012-01-01

    We have used a relatively long, contiguous VHF observation of a bright cosmic radio source (Cygnus A) with the Very Large Array (VLA) to demonstrate the capability of this instrument to study the ionosphere. This interferometer, and others like it, can observe ionospheric total electron content (TEC) fluctuations on a much wider range of scales than is possible with many other instruments. We have shown that with a bright source, the VLA can measure differential TEC values between pairs of antennas (delta-TEC) with an precision of 0.0003 TECU. Here, we detail the data reduction and processing techniques used to achieve this level of precision. In addition, we demonstrate techniques for exploiting these high-precision delta-TEC measurements to compute the TEC gradient observed by the array as well as small-scale fluctuations within the TEC gradient surface. A companion paper details specialized spectral analysis techniques used to characterize the properties of wave-like fluctuations within this data.

  9. Development of the optical system for the SST-1M telescope of the Cherenkov Telescope Array observatory

    CERN Document Server

    Seweryn, K; Błocki, J.; Bogacz, L.; Bulik, T.; Cadoux, F.; Christov, A.; Chruślińska, M.; Curyło, M.; della Volpe, D.; Dyrda, M.; Favre, Y.; Frankowski, A.; Grudnik, Ł.; Grudzińska, M.; Heller, M.; Idźkowski, B.; Jamrozy, M.; Janiak, M.; Kasperek, J.; Lalik, K.; Lyard, E.; Mach, E.; Mandat, D.; Marszałek, A.; Michałowski, J.; Moderski, R.; Montaruli, T.; Neronov, A.; Niemiec, J.; Ostrowski, M.; Paśko, P.; Pech, M.; Porcelli, A.; Prandini, E.; Pueschel, E.; Rajda, P.; Rameez, M.; Rozwadowski, P.; Schioppa, E. jr; Schovanek, P.; Skowron, K.; Sliusar, V.; Sowiński, M.; Stawarz, Ł.; Stodulska, M.; Stodulski, M.; Toscano, S.; Pujadas, I. Troyano; Walter, R.; Wiȩcek, M.; Zagdański, A.; Ziȩtara, K.; Żychowski, P.; Barciński, T.; Karczewski, M.; Kukliński, J. Nicolau; Płatos, Ł.; Rataj, M.; Wawer, P.; Wawrzaszek, R.

    2015-01-01

    The prototype of a Davies-Cotton small size telescope (SST-1M) has been designed and developed by a consortium of Polish and Swiss institutions and proposed for the Cherenkov Telescope Array (CTA) observatory. The main purpose of the optical system is to focus the Cherenkov light emitted by extensive air showers in the atmosphere onto the focal plane detectors. The main component of the system is a dish consisting of 18 hexagonal mirrors with a total effective collection area of 6.47 m2 (including the shadowing and estimated mirror reflectivity). Such a solution was chosen taking into account the analysis of the Cherenkov light propagation and based on optical simulations. The proper curvature and stability of the dish is ensured by the mirror alignment system and the isostatic interface to the telescope structure. Here we present the design of the optical subsystem together with the performance measurements of its components.

  10. Development of a nano-technology based low-LET multi-microbeam array single cell irradiation system

    International Nuclear Information System (INIS)

    A novel single cell irradiation system using carbon nano-tube (CNT) based field emission technology is proposed. The system can produce electron microbeam at a large range of pulsation frequencies and dose rates with energy between 20 and 60 keV. Different from any existing single beam microbeam device, the CNT-based system can have 10,000 microbeam pixels, each is ∼10 μm in size and individually controlled. Microscope imaging will be used for targeting cell(s) and the coordinate(s) identification. A single cell or large number of individually selected cells can be simultaneously irradiated under real time microscope observation. This poster reports our preliminary results in the initial stage of the CNT multi-pixel microbeam array development - prototype single pixel CNT microbeam device development. (authors)

  11. High-speed, automatic controller design considerations for integrating array processor, multi-microprocessor, and host computer system architectures

    Science.gov (United States)

    Jacklin, S. A.; Leyland, J. A.; Warmbrodt, W.

    1985-01-01

    Modern control systems must typically perform real-time identification and control, as well as coordinate a host of other activities related to user interaction, online graphics, and file management. This paper discusses five global design considerations which are useful to integrate array processor, multimicroprocessor, and host computer system architectures into versatile, high-speed controllers. Such controllers are capable of very high control throughput, and can maintain constant interaction with the nonreal-time or user environment. As an application example, the architecture of a high-speed, closed-loop controller used to actively control helicopter vibration is briefly discussed. Although this system has been designed for use as the controller for real-time rotorcraft dynamics and control studies in a wind tunnel environment, the controller architecture can generally be applied to a wide range of automatic control applications.

  12. Passive microfluidic array card and reader

    Energy Technology Data Exchange (ETDEWEB)

    Dugan, Lawrence Christopher (Modesto, CA); Coleman, Matthew A. (Oakland, CA)

    2011-08-09

    A microfluidic array card and reader system for analyzing a sample. The microfluidic array card includes a sample loading section for loading the sample onto the microfluidic array card, a multiplicity of array windows, and a transport section or sections for transporting the sample from the sample loading section to the array windows. The microfluidic array card reader includes a housing, a receiving section for receiving the microfluidic array card, a viewing section, and a light source that directs light to the array window of the microfluidic array card and to the viewing section.

  13. Determination of salbutamol in human plasma and urine by high-performance liquid chromatography with a coulometric electrode array system.

    Science.gov (United States)

    Zhang, X Z; Gan, Y R; Zhao, F N

    2004-01-01

    A method is developed to determine salbutamol in human plasma and urine using high-performance liquid chromatography (HPLC) with a coulometric electrode array system, based on the electrochemical behavior of salbutamol at graphite electrode. The mobile phase component A is 30 mM sodium dihydroxy phosphate-30 mM triethylamine and is adjusted to pH 6.0 with 20% phosphate acid. The mobile phase component B is methanol. The optimized mobile phase composition was A and B in the proportion of 90:10 (v/v). Paracetamol is selected as the external standard. The human plasma and urine samples are pretreated using solid-phase extraction cartridges (Sep-Pak Silica), and the eluting solution is monitored by the coulometric electrode array system. The electrode potentials are set at 300, 400, 550, and 650 mV, respectively. Calibration curves show good linearity, and the recovery of salbutamol proves to be constant and unaffected by the concentration of the drug. This method, developed using HPLC-electrochemical detection, is reproducible and sensitive enough for the determination of salbutamol in human plasma and urine. PMID:15189600

  14. Numerical Simulation of Refractive-Microlensed HgCdTe Infrared Focal Plane Arrays Operating in Optical Systems

    Science.gov (United States)

    Li, Yang; Ye, Zhen-Hua; Hu, Wei-Da; Lei, Wen; Gao, Yan-Lin; He, Kai; Hua, Hua; Zhang, Peng; Chen, Yi-Yu; Lin, Chun; Hu, Xiao-Ning; Ding, Rui-Jun; He, Li

    2014-08-01

    The optoelectronic performance of the mid-wavelength HgCdTe infrared focal plane array (IRFPA) with refractive microlenses integrated on its CdZnTe substrate has been numerically simulated. A reduced light-distribution model based on scalar Kirchhoff diffraction theory was adopted to reveal the true behavior of IRFPAs operating in an optical system under imaging conditions. The pixel crosstalk obtained and the energy-gathering characteristics demonstrated that the microlenses can delay the rise in crosstalk when the image point shifts toward pixel boundaries, and can restrict the major optical absorption process in any case within a narrow region around the pixel center. The dependence of the microlenses' effects on the system's properties was also analyzed; this showed that intermediate relative aperture and small microlens radius are required for optimized device performance. Simulation results also indicated that for detectors farther from the center of the field of view, the efficacy of microlenses in crosstalk suppression and energy gathering is still maintained, except for a negligible difference in the lateral magnification from an ordinary array without microlenses.

  15. Utilization of a cryo-prober system for operation of a pulse-driven josephson junction array

    Science.gov (United States)

    Maruyama, M.; Urano, C.; Kaneko, N.; Yamamori, H.; Shoji, A.; Maezawa, M.; Hashimoto, Y.; Suzuki, H.; Nagasawa, S.; Satoh, T.; Hidaka, M.; Kiryu, S.

    2010-06-01

    We demonstrated the operation of pulse-driven Josephson junction arrays (JJAs) for AC voltage standard using a wideband cryo-prober system with a 4-K Gifford-MacMahon (GM) cooler. This unique system was originally developed for high-speed network switch applications of rapid-single-flux-quantum (RSFQ) circuits and enables wideband data transmission at bit rates of higher than 10 Gbps between room-temperature and cryogenic environments. JJA chips were fabricated using NbN-based superconductor-normal metal-superconductor (SNS) junctions. A 5-mm chip was mounted on a 16-mm chip carrier using flip-chip bonding technology for probe contact. To obtain bipolar output voltages, we tried two types of testing based on the AC coupling technique proposed by the National Institute of Standards and Technology (NIST). A pulse pattern generator (PPG) with a large memory of 134 Mbit was used for covering a wide frequency range of output signals. As a result, we succeeded in bipolar operation of the JJA, generating waveforms at frequencies from 60 Hz to several tens of kilo hertz. The maximum rms voltage obtained for a single array was 12.7 mV. The observed spurious level was lower than -93 dBc at 16 kHz.

  16. Design for the correction system of the real time nonuniformity of large area-array CCD image

    Science.gov (United States)

    Wang, Yan; Li, Chunmei; Lei, Ning

    2012-10-01

    With the robust thriving of aviation cameras and remote sensing technology, the linear-array CCD (charge-coupled device) and area CCD have developed toward large area CCD, which has a broad coverage and avoids the difficulty in jointing small area CCDs in addition to improving time resolution. However, due to the high amount of pixels and channels of large area CCD, photo-response non-uniformity (PRNU) is severe. In this paper, a real time non-uniformity correction system is introduced for a sort of large area full frame transfer CCD. First, the correction algorithm is elaborated according to CCD's working principle. Secondly, due to the high number of pixels and correction coefficient, ordinary chip memory cannot meet the requirement. The combination of external flash memory and DDR described in the paper satisfies large capacity memory and rapid real time correction. The methods and measurement steps for obtaining correction factors are provided simultaneously. At the end, an imaging test is made. The non-uniformity of the image is reduced to 0.38 % from the pre-correction 2.96 %, achieving an obvious reduction of non-uniformity. The result shows that the real time non-uniformity correction system can meet the demands of large area-array CCD.

  17. Utilization of a cryo-prober system for operation of a pulse-driven josephson junction array

    International Nuclear Information System (INIS)

    We demonstrated the operation of pulse-driven Josephson junction arrays (JJAs) for AC voltage standard using a wideband cryo-prober system with a 4-K Gifford-MacMahon (GM) cooler. This unique system was originally developed for high-speed network switch applications of rapid-single-flux-quantum (RSFQ) circuits and enables wideband data transmission at bit rates of higher than 10 Gbps between room-temperature and cryogenic environments. JJA chips were fabricated using NbN-based superconductor-normal metal-superconductor (SNS) junctions. A 5-mm chip was mounted on a 16-mm chip carrier using flip-chip bonding technology for probe contact. To obtain bipolar output voltages, we tried two types of testing based on the AC coupling technique proposed by the National Institute of Standards and Technology (NIST). A pulse pattern generator (PPG) with a large memory of 134 Mbit was used for covering a wide frequency range of output signals. As a result, we succeeded in bipolar operation of the JJA, generating waveforms at frequencies from 60 Hz to several tens of kilo hertz. The maximum rms voltage obtained for a single array was 12.7 mV. The observed spurious level was lower than -93 dBc at 16 kHz.

  18. An ultra-wideband radar imaging system using a two-dimensional multiple-input multiple-output (MIMO) transducer array

    OpenAIRE

    Fortuny-Guasch, J.; Martinez, A.; Yarovoy, A.; Zhuge, X.; Lerat, J.M.; Duchesne, L

    2011-01-01

    A radar transducer array (12) for an ultra-wideband imaging radar system (10) operating at a reference wavelength ?c comprises transmission antenna elements (14) or reception antenna elements and reception antenna elements (16), which are located at specific locations of the array plane in such a way that high image quality is achieved with a minimum number of antenna elements (14, 16), resulting in less complex hardware as well as significantly reduced computational effort.

  19. Local Oscillator Sub-Systems for Array Receivers in the 1-3 THz Range

    Science.gov (United States)

    Mehdi, Imran; Siles, Jose V.; Maestrini, Alain; Lin, Robert; Lee, Choonsup; Schlecht, Erich; Chattopadhyay, Goutam

    2012-01-01

    Recent results from the Heterodyne Instrument for the Far-Infrared (HIFI) on the Herschel Space Telescope have confirmed the usefulness of high resolution spectroscopic data for a better understanding of our Universe. This paper will explore the current status of tunable local oscillator sources with emphasis on building a multi-pixel LO subsystem for the scientifically important CII line around 1908 GHz. Recent results have shown that over 50 microwatts of output power at 1.9 THz are possible with an optimized single pixel LO chain. These power levels are now sufficient to pump array receivers in this frequency range. Further power enhancement can be obtained by cooling the chain to 120 K or by utilizing in-phase power combining technology.

  20. Development of a Photovoltaic Array Emulator System in Real Time Considering Climatic Conditions Variations

    Directory of Open Access Journals (Sweden)

    Camilo E. Ardila-Franco

    2013-11-01

    Full Text Available This paper presents the development of an emulator that has the ability to replicate, in real time, the behavior of photovoltaic panels (PV arrays considering different conditions of irradiation and temperature for each one. The emulator consists of a data acquisition card, a programmable source and a computer. It is based on the bypass diode model that provides a better approximation to real operating conditions. The solution is computed by a simplified equation that uses the Lambert W function, which reduces the computation time. After that, it generates a solution table of values of current as a function of voltage on terminals, temperature and irradiation. Real-time emulation is performed by means of a search algorithm in the solutions table of the closest value to the voltage imposed on the terminals.

  1. Polyacrylamide gel electrophoresis of soybean seed proteins

    OpenAIRE

    W. Lassocińsk; J. S. Knypl

    2015-01-01

    Four major and 14 minor protein bands were detected when total salt soluble proteins of soybean (Glycine max cultivar Warszawska) seed were subjected to polyacrylamide gel electrophoresis under nondissociating conditions, and 16 protein bands were detected under dissociating conditions. Molecular weights of three major protein fractions in PAGE SDS were determined for around 18 500, 36 000 and 80 000 daltons.

  2. The repton model of gel electrophoresis

    OpenAIRE

    Barkema, G. T.; Newman, M. E. J.

    1996-01-01

    We discuss the repton model of agarose gel electrophoresis of DNA. We review previous results, both analytic and numerical, as well as presenting a new numerical algorithm for the efficient simulation of the model, and suggesting a new approach to the model's analytic solution.

  3. Matching Two-dimensional Gel Electrophoresis' Spots

    DEFF Research Database (Denmark)

    Dos Anjos, António; AL-Tam, Faroq; Shahbazkia, Hamid Reza;

    2012-01-01

    This paper describes an approach for matching Two-Dimensional Electrophoresis (2-DE) gels' spots, involving the use of image registration. The number of false positive matches produced by the proposed approach is small, when compared to academic and commercial state-of-the-art approaches. This ar...

  4. Contemporary sample stacking in analytical electrophoresis

    Czech Academy of Sciences Publication Activity Database

    Malá, Zdeňka; Šlampová, Andrea; Křivánková, Ludmila; Gebauer, Petr; Boček, Petr

    2015-01-01

    Roč. 36, č. 1 (2015), s. 15-35. ISSN 0173-0835 R&D Projects: GA ČR(CZ) GA13-05762S Institutional support: RVO:68081715 Keywords : biological samples * stacking * trace analysis * zone electrophoresis Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.028, year: 2014

  5. Analysis and development of a low-cost permanent magnet brushless DC motor drive for PV-array fed water pumping system

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Bhim; Swamy, C.L. Putta; Singh, B.P. [Department of Electrical Engineering, Indian Institute of Technology, Delhi, New Delhi (India)

    1997-12-19

    This paper deals with the analysis and development of a permanent magnet brushless DC (PMBLDC) motor drive coupled to a pump load powered by solar photovoltaic (PV) array for water pumping system. A simple low-cost prototype controller has been designed and developed without current and position sensors which reduces drastically the overall cost of the drive system. This controller is used to test the dynamic behavior of the PMBLDC motor drive system. The mathematical model of the system is developed with a view to carry out a comparison between experimental and simulated response of the drive system. A simple filter circuit is incorporated in between PV-array and an inverter to reduce ripples and to improve the performance of the PV-array. The necessary computer algorithm is developed to analyze the performance under different conditions of varying solar insolation for a pump load

  6. Diode Laser Arrays

    Science.gov (United States)

    Botez, Dan; Scifres, Don R.

    1994-08-01

    This book provides a comprehensive overview of the fundamental principles and applications of semiconductor diode laser arrays. All of the major types of arrays are discussed in detail, including coherent, incoherent, edge- and surface-emitting, horizontal- and vertical-cavity, individually addressed, lattice- matched and strained-layer systems. The initial chapters cover such topics as lasers, amplifiers, external-cavity control, theoretical modeling, and operational dynamics. Spatially incoherent arrays are then described in detail, and the uses of vertical-cavity surface emitter and edge-emitting arrays in parallel optical-signal processing and multi-channel optical recording are discussed. Researchers and graduate students in solid state physics and electrical engineering studying the properties and applications of such arrays will find this book invaluable.

  7. Radar techniques using array antennas

    CERN Document Server

    Wirth, Wulf-Dieter

    2013-01-01

    Radar Techniques Using Array Antennas is a thorough introduction to the possibilities of radar technology based on electronic steerable and active array antennas. Topics covered include array signal processing, array calibration, adaptive digital beamforming, adaptive monopulse, superresolution, pulse compression, sequential detection, target detection with long pulse series, space-time adaptive processing (STAP), moving target detection using synthetic aperture radar (SAR), target imaging, energy management and system parameter relations. The discussed methods are confirmed by simulation stud

  8. A new data acquisition and imaging system for nuclear microscopy based on a Field Programmable Gate Array card

    Energy Technology Data Exchange (ETDEWEB)

    Bettiol, A.A. [Centre for Ion Beam Applications, Department of Physics, National University of Singapore, Blk S7 2 Science Dr. 3, Singapore 117542 (Singapore)], E-mail: phybaa@nus.edu.sg; Udalagama, C.; Watt, F. [Centre for Ion Beam Applications, Department of Physics, National University of Singapore, Blk S7 2 Science Dr. 3, Singapore 117542 (Singapore)

    2009-06-15

    The introduction of the new Field Programmable Gate Array (FPGA) cards by National Instruments has made it possible for the first time to develop reconfigurable custom data acquisition hardware easily with the LabVIEW programming environment. Data acquisition issues such as precise timing for scanning and operating system latencies can now be easily overcome using this new technology because the data acquisition software is embedded in the FPGA chip on the card. In this paper we present the first results of the new data acquisition system developed at the Centre for Ion Beam Applications (CIBA), National University of Singapore using the new National Instruments cards in conjunction with rack mountable Wilkinson type ADCs.

  9. Develop silicone encapsulation systems for terrestrial silicon solar arrays. First quarterly progress report, February 15, 1978--June 30, 1978

    Energy Technology Data Exchange (ETDEWEB)

    1978-07-10

    This study is directed toward the development of a cost effective encapsulation system for photovoltaic modules using silicone based materials. This is a cooperative effort between Dow Corning, the major supplier of silicones and silicone intermediates, and Spectrolab a leading photovoltaic array manufacturer. The total contract effort has been divided into four tasks: technology review, generation of screening concepts, assessment of encapsulation concepts, and evaluation of encapsulation concepts. A review of technology pertinent to the use and weatherability of silicone based materials and a plan for screening encapsulation concepts are presented. The technology review covered: the performance of clear silicones in weathering and stress environments, photovoltaic industry experience with silicone materials used in photovoltaic systems, and silicones used in the protection of electronic devices.

  10. Using Gel Electrophoresis To Illustrate Protein Diversity and Isoelectric Point.

    Science.gov (United States)

    Browning, Mark; Vanable, Joseph

    2002-01-01

    Demonstrates the differences in protein structures by focusing on isoelectric point with an experiment that is observable under certain pH levels in gel electrophoresis. Explains the electrophoresis procedure and reports results of the experiments. (YDS)

  11. A decentralized procedure for structural health monitoring of uncertain nonlinear systems provided with dense active sensor arrays

    International Nuclear Information System (INIS)

    A numerical simulation study is conducted to evaluate the feasibility of a proposed algorithm for testing and analyzing the vibration signature of complex, nonlinear and uncertain structural systems provided with dense, active sensor arrays that have the capability to generate local probing signals. The proposed algorithm for 'decentralized' identification of the parameters of a highly reduced-order model can be easily embedded in simple processors that are incorporated in modern wireless sensors, without the need for demanding computational resources or inter-sensor communications. It is shown that the proposed estimation approach, in which a reduced-order equivalent single-degree-of-freedom linear system is identified to match the observed response of a specific sensor/actuator pair, is capable of detecting relatively small changes in the estimated system parameters. These parameters can be directly correlated with physically meaningful measures of the structural dynamic properties of the system being monitored. A parametric study is conducted to determine the robustness of the proposed approach with regard to variation in 'damage' location relative to the sensor location, 'damage' magnitude, scatter in the estimated system parameters due to the stochastic nature of the nonlinear system and variability (uncertainty) in the reference system parameters. It is shown that the proposed approach is viable for implementations involving sensor 'motes' with limited storage and computational resources

  12. ISS Solar Array Management

    Science.gov (United States)

    Williams, James P.; Martin, Keith D.; Thomas, Justin R.; Caro, Samuel

    2010-01-01

    The International Space Station (ISS) Solar Array Management (SAM) software toolset provides the capabilities necessary to operate a spacecraft with complex solar array constraints. It monitors spacecraft telemetry and provides interpretations of solar array constraint data in an intuitive manner. The toolset provides extensive situational awareness to ensure mission success by analyzing power generation needs, array motion constraints, and structural loading situations. The software suite consists of several components including samCS (constraint set selector), samShadyTimers (array shadowing timers), samWin (visualization GUI), samLock (array motion constraint computation), and samJet (attitude control system configuration selector). It provides high availability and uptime for extended and continuous mission support. It is able to support two-degrees-of-freedom (DOF) array positioning and supports up to ten simultaneous constraints with intuitive 1D and 2D decision support visualizations of constraint data. Display synchronization is enabled across a networked control center and multiple methods for constraint data interpolation are supported. Use of this software toolset increases flight safety, reduces mission support effort, optimizes solar array operation for achieving mission goals, and has run for weeks at a time without issues. The SAM toolset is currently used in ISS real-time mission operations.

  13. High Throughput Sample Preparation and Analysis for DNA Sequencing, PCR and Combinatorial Screening of Catalysis Based on Capillary Array Technique

    Energy Technology Data Exchange (ETDEWEB)

    Yonghua Zhang

    2002-05-27

    Sample preparation has been one of the major bottlenecks for many high throughput analyses. The purpose of this research was to develop new sample preparation and integration approach for DNA sequencing, PCR based DNA analysis and combinatorial screening of homogeneous catalysis based on multiplexed capillary electrophoresis with laser induced fluorescence or imaging UV absorption detection. The author first introduced a method to integrate the front-end tasks to DNA capillary-array sequencers. protocols for directly sequencing the plasmids from a single bacterial colony in fused-silica capillaries were developed. After the colony was picked, lysis was accomplished in situ in the plastic sample tube using either a thermocycler or heating block. Upon heating, the plasmids were released while chromsomal DNA and membrane proteins were denatured and precipitated to the bottom of the tube. After adding enzyme and Sanger reagents, the resulting solution was aspirated into the reaction capillaries by a syringe pump, and cycle sequencing was initiated. No deleterious effect upon the reaction efficiency, the on-line purification system, or the capillary electrophoresis separation was observed, even though the crude lysate was used as the template. Multiplexed on-line DNA sequencing data from 8 parallel channels allowed base calling up to 620 bp with an accuracy of 98%. The entire system can be automatically regenerated for repeated operation. For PCR based DNA analysis, they demonstrated that capillary electrophoresis with UV detection can be used for DNA analysis starting from clinical sample without purification. After PCR reaction using cheek cell, blood or HIV-1 gag DNA, the reaction mixtures was injected into the capillary either on-line or off-line by base stacking. The protocol was also applied to capillary array electrophoresis. The use of cheaper detection, and the elimination of purification of DNA sample before or after PCR reaction, will make this approach an

  14. Anti-cas spacers in orphan CRISPR4 arrays prevent uptake of active CRISPR-Cas I-F systems.

    Science.gov (United States)

    Almendros, Cristóbal; Guzmán, Noemí M; García-Martínez, Jesús; Mojica, Francisco J M

    2016-01-01

    Archaea and bacteria harbour clustered regularly interspaced short palindromic repeats (CRISPR) loci. These arrays encode RNA molecules (crRNA), each containing a sequence of a single repeat-intervening spacer. The crRNAs guide CRISPR-associated (Cas) proteins to cleave nucleic acids complementary to the crRNA spacer, thus interfering with targeted foreign elements. Notably, pre-existing spacers may trigger the acquisition of new spacers from the target molecule by means of a primed adaptation mechanism. Here, we show that naturally occurring orphan CRISPR arrays that contain spacers matching sequences of the cognate (absent) cas genes are able to elicit both primed adaptation and direct interference against genetic elements carrying those genes. Our findings show the existence of an anti-cas mechanism that prevents the transfer of a fully equipped CRISPR-Cas system. Hence, they suggest that CRISPR immunity may be undesired by particular prokaryotes, potentially because they could limit possibilities for gaining favourable sequences by lateral transfer. PMID:27573106

  15. Ligand-assisted capillary electrophoresis separations of the lanthanides

    International Nuclear Information System (INIS)

    Capillary electrophoresis is used with simple organic ligands added to the electrolyte matrix to achieve separation of the individual lanthanide cations. Results for acetate (AC-) and malonate (MA-) yield good resolution for the lighter lanthanides, but not the heavier lanthanides. In contrast, α-hydroxyisobutyrate (HIB-) gives complete resolution for all of the lanthanide cations. These results are related to the complexation chemistry between the lanthanides and the ligands across the lanthanide series. In addition, preliminary results for lanthanide separations using AC- in mixed methanol:water solvent systems are provided. The presence of methanol improves resolution but slows the separation. (author)

  16. STUDY OF CAPILLARY ELECTROPHORESIS ON MICROCHIP BASED ON MEMS

    Institute of Scientific and Technical Information of China (English)

    WangMing; LiWei; 等

    2002-01-01

    Using a standard photolithographical procedure,chenmical wet etching and thermal diffusion bonding technology,a chemical analysis device for Capillary Electrophoresis(CE) has been microfabricated on a planar glass substrate with a cross-column geometry.The channels on the microchip substrate are about 50um deep and 150um wide.By employing amino acids derived from 2,4-DiNitroFluoroBenzen(DNFB) on CE chip channels,the sample manipulating system is studied based on the principle of electrodynamics.

  17. All-Optical Modulation of Localized Surface Plasmon Coupling in a Hybrid System Composed of Photo-Switchable Gratings and Au Nanodisk Arrays

    Science.gov (United States)

    Liu, Yan Jun; Zheng, Yue Bing; Liou, Justin; Chiang, I-Kao; Khoo, Iam Choon; Huang, Tony Jun

    2011-01-01

    We conduct a real-time study of all-optical modulation of localized surface plasmon resonance (LSPR) coupling in a hybrid system that integrates a photo-switchable optical grating with a gold nanodisk array. This hybrid system enables us to investigate two important interactions: 1) LSPR-enhanced grating diffraction, and 2) diffraction-mediated LSPR in the Au nanodisk array. The physical mechanism underlying these interactions was analyzed and experimentally confirmed. With its advantages in cost-effective fabrication, easy integration, and all-optical control, the hybrid system described in this work could be valuable in many nanophotonic applications. PMID:21643480

  18. The Alignment System for a Medium-Sized Schwarzschild-Couder Telescope Prototype for the Cherenkov Telescope Array

    Science.gov (United States)

    Ribeiro, Deivid; Humensky, Brian; Nieto, Daniel; V Vassiliev Group in UCLA division of Astronomy and Astrophysics, P Kaaret Group at Iowa University Department of Physics and Astronomy, CTA Consortium

    2016-01-01

    The Cherenkov Telescope Array (CTA) is an international project for a next-generation ground-based gamma-ray observatory. CTA, conceived as an array of tens of imaging atmospheric Cherenkov telescopes, comprising small, medium and large-size telescopes, is aiming to improve on the sensitivity of current-generation experiments by an order of magnitude and provide energy coverage from 20 GeV to more than 300 TeV. The Schwarzschild-Couder design is a candidate 9-m diameter medium-sized telescope featuring a novel aplanatic two-mirror optical design capable of a wide field of view with significantly improved imaging resolution as compared to the traditional Davies-Cotton optical design. Achieving this imaging resolution imposes strict mirror alignment requirements that necessitate a sophisticated alignment system. This system uses a collection of position sensors between panels to determine the relative position of adjacent panels; each panel is mounted on a Stewart platform to allow motion control with six degrees of freedom, facilitating the alignment of the optical surface for the segmented primary and secondary mirrors. Alignments of the primary and secondary mirrors and the camera focal plane with respect to each other are performed utilizing a set of CCD cameras which image LEDs placed on the mirror panels to measure relative translation, and custom-built auto-collimators to measure relative tilt between the primary and secondary mirrors along the optical axis of the telescope. In this contribution we present the status of the development of the SC optical alignment system, soon to be materialized in a full-scale prototype SC medium-size telescope (pSCT) at the Fred Lawrence Whipple Observatory in southern Arizona.

  19. Dense-array concentrator photovoltaic system using non-imaging dish concentrator and crossed compound parabolic concentrator

    Science.gov (United States)

    Chong, Kok-Keong; Yew, Tiong-Keat; Wong, Chee-Woon; Tan, Ming-Hui; Tan, Woei-Chong; Lai, An-Chow; Lim, Boon-Han; Lau, Sing-Liong; Rahman, Faidz Abdul

    2015-04-01

    Solar concentrating device plays an important role by making use of optical technology in the design, which can be either reflector or lens to deliver high flux of sunlight onto the Concentrator Photovoltaic (CPV) module receiver ranging from hundreds to thousand suns. To be more competitive compared with fossil fuel, the current CPV systems using Fresnel lens and Parabolic dish as solar concentrator that are widely deployed in United States, Australia and Europe are facing great challenge to produce uniformly focused sunlight on the solar cells as to reduce the cost of electrical power generation. The concept of non-imaging optics is not new, but it has not fully explored by the researchers over the world especially in solving the problem of high concentration solar energy, which application is only limited to be a secondary focusing device or low concentration device using Compound Parabolic Concentrator. With the current advancement in the computer processing power, we has successfully invented the non-imaging dish concentrator (NIDC) using numerical simulation method to replace the current parabolic dish as primary focusing device with high solar concentration ratio (more than 400 suns) and large collective area (from 25 to 125 m2). In this paper, we disclose our research and development on dense array CPV system based on non-imaging optics. The geometry of the NIDC is determined using a special computational method. In addition, an array of secondary concentrators, namely crossed compound parabolic concentrators, is also proposed to further focus the concentrated sunlight by the NIDC onto active area of solar cells of the concentrator photovoltaic receiver. The invention maximizes the absorption of concentrated sunlight for the electric power generation system.

  20. Concurrent array-based queue

    Energy Technology Data Exchange (ETDEWEB)

    Heidelberger, Philip; Steinmacher-Burow, Burkhard

    2015-01-06

    According to one embodiment, a method for implementing an array-based queue in memory of a memory system that includes a controller includes configuring, in the memory, metadata of the array-based queue. The configuring comprises defining, in metadata, an array start location in the memory for the array-based queue, defining, in the metadata, an array size for the array-based queue, defining, in the metadata, a queue top for the array-based queue and defining, in the metadata, a queue bottom for the array-based queue. The method also includes the controller serving a request for an operation on the queue, the request providing the location in the memory of the metadata of the queue.