WorldWideScience

Sample records for around-the-objective total internal

  1. Total internal reflection laser tools and methods

    Energy Technology Data Exchange (ETDEWEB)

    Zediker, Mark S.; Faircloth, Brian O.; Kolachalam, Sharath K.; Grubb, Daryl L.

    2016-02-02

    There is provided high power laser tools and laser heads that utilize total internal reflection ("TIR") structures to direct the laser beam along a laser beam path within the TIR structure. The TIR structures may be a TIR prism having its hypotenuse as a TIR surface.

  2. Total internal reflection tomography of small objects

    International Nuclear Information System (INIS)

    The multiple signal classification (MUSIC) imaging method is applied to determine the locations of a collection of small anisotropic spherical scatterers in the framework of the total internal reflection tomography. Multiple scattering between scatterers is considered and the inverse scattering problem is nonlinear, which, however, is solved by the proposed fast analytical approach where no associated forward problem is iteratively evaluated. The paper also discusses the role of the polarization of incidence waves, the incidence angle, the separation of scatterers from the surface of the substrate, and the level of noise on the resolution of imaging.

  3. Total Internal Reflection of Orbital Angular Momentum Beams

    OpenAIRE

    Loffler W.; Hermosa N.; Aiello A.; Woerdman J.P.

    2012-01-01

    We investigate how beams with orbital angular momentum (OAM) behave under total internal reflection. This is studied in two complementary experiments: In the first experiment, we study geometric shifts of OAM beams upon total internal reflection (Goos-H\\"anchen and Imbert-Fedorov shifts, for each the spatial and angular variant), and in the second experiment we determine changes in the OAM mode spectrum of a beam, again upon total internal reflection. As a result we find that in the first cas...

  4. Total internal reflection of orbital angular momentum beams

    International Nuclear Information System (INIS)

    We investigate how beams with orbital angular momentum (OAM) behave under total internal reflection. This is studied in two complementary experiments: in the first experiment, we study geometric shifts of OAM beams upon total internal reflection (Goos–Hänchen and Imbert–Fedorov shifts, for each the spatial and angular variant), and in the second experiment we determine changes in the OAM mode spectrum of a beam, again upon total internal reflection. As a result we find that, in the first case, the shifts are independent of OAM and beam focusing, while in the second case, modifications in the OAM spectrum occur which depend on the input OAM mode as well as on the beam focusing. This is investigated by experiment and theory. We also show how the two methods, beam shifts on the one hand, and OAM spectrum changes on the other, are related theoretically. (paper)

  5. Total Internal Reflection of Orbital Angular Momentum Beams

    CERN Document Server

    Löffler, W; Aiello, Andrea; Woerdman, J P

    2012-01-01

    We investigate how beams with orbital angular momentum (OAM) behave under total internal reflection. This is studied in two complementary experiments: In the first experiment, we study geometric shifts of OAM beams upon total internal reflection (Goos-H\\"anchen and Imbert-Fedorov shifts, for each the spatial and angular variant), and in the second experiment we determine changes in the OAM mode spectrum of a beam, again upon total internal reflection. As a result we find that in the first case, the shifts are independent of OAM and beam focussing, while in the second case, modifications in the OAM spectrum occur which depend on the input OAM mode as well as on the beam focussing. This is investigated by experiment and theory. We also show how the two methods, beam shifts on the one hand, and OAM spectrum changes on the other, are related theoretically.

  6. Breakthroughs in Photonics 2014: Relaxed Total Internal Reflection

    CERN Document Server

    Jahani, Saman

    2015-01-01

    Total internal reflection (TIR) is a ubiquitous phenomenon used in photonic devices ranging from waveguides and resonators to lasers and optical sensors. Controlling this phenomenon and light confinement are keys to the future integration of nanoelectronics and nanophotonics on the same silicon platform. We introduced the concept of relaxed total internal reflection in 2014 to control evanescent waves generated during TIR. These unchecked evanescent waves are the fundamental reason photonic devices are inevitably diffraction-limited and cannot be miniaturized. Our key design concept is the engineered anisotropy of the medium into which the evanescent wave extends thus allowing for skin depth engineering without any metallic components. In this article, we give an overview of our approach and compare it to key classes of photonic devices such as plasmonic waveguides, photonic crystal waveguides and slot waveguides. We show how our work can overcome a long standing issue in photonics nanoscale light confinement...

  7. Comment on 'Photonic tunneling time in frustrated total internal reflection'

    International Nuclear Information System (INIS)

    This is a comment on Stahlhofen's paper [Phys. Rev. A 62, 012112 (2000)]. It is shown by stationary-phase theory that the Goos-Haenchen shift in frustrated total internal reflection (FTIR) is not independent of the group delay (or phase time in the literature). The group delay involves the contribution of Goos-Haenchen shift and is always larger than zero in FTIR. It is also shown that the group delay in the two-dimensional (2D) optical FTIR can be written in the same form as that of the group delay in the 1D quantum tunneling in the sense that the group delay is the derivative of the total phase shift with respect to the angular frequency

  8. Frustrated total internal reflection and the illusion of superluminal propagation

    CERN Document Server

    Brudny, Vera L

    2008-01-01

    We analyze the propagation of a pulse across a vacuum gap separating opposite flat parallel faces of two transparent dielectrics by means of an explicitly causal and retarded propagator constructed directly from the free-space wave equation. Nevertheless, our approach yields apparently superluminal propagation for the case of frustrated total internal reflection (FTIR), that is, a transmitted wave packet appears on the far side of the gap at the same time that the corresponding incident packet crosses the front one. Thus, in this example superluminality is just an illusion, being consistent with both casuality and classical electrodynamics. We study the origin of the apparent superluminality in this case, which is inherent to light pulse propagation in free space and does not depend on the particulars of light-matter interaction, and find that it is due to propagation from the lateral wings of the incident pulse to the central part of the transmitted pulse. Thus, notwithstanding their similarities, FTIR is no...

  9. Single-Molecule Total Internal Reflection Fluorescence Microscopy.

    Science.gov (United States)

    Kudalkar, Emily M; Davis, Trisha N; Asbury, Charles L

    2016-01-01

    The advent of total internal reflection fluorescence (TIRF) microscopy has permitted visualization of biological events on an unprecedented scale: the single-molecule level. Using TIRF, it is now possible to view complex biological interactions such as cargo transport by a single molecular motor or DNA replication in real time. TIRF allows for visualization of single molecules by eliminating out-of-focus fluorescence and enhancing the signal-to-noise ratio. TIRF has been instrumental for studying in vitro interactions and has also been successfully implemented in live-cell imaging. Visualization of cytoskeletal structures and dynamics at the plasma membrane, such as endocytosis, exocytosis, and adhesion, has become much clearer using TIRF microscopy. Thanks to recent advances in optics and commercial availability, TIRF microscopy is becoming an increasingly popular and user-friendly technique. In this introduction, we describe the fundamental properties of TIRF microscopy and the advantages of using TIRF for single-molecule investigation. PMID:27140922

  10. Coverslip Cleaning and Functionalization for Total Internal Reflection Fluorescence Microscopy.

    Science.gov (United States)

    Kudalkar, Emily M; Deng, Yi; Davis, Trisha N; Asbury, Charles L

    2016-01-01

    Total internal reflection fluorescence (TIRF) microscopy allows visualization of biological events at the single-molecule level by restricting excitation to a precise focal plane near the coverslip and eliminating out-of-focus fluorescence. The quality of TIRF imaging relies on a high signal-to-noise ratio and therefore it is imperative to prevent adherence of molecules to the glass coverslip. Nonspecific interactions can make it difficult to distinguish true binding events and may also interfere with accurate quantification of background noise. In addition, nonspecific binding of the fluorescently tagged protein will lower the effective working concentration, thereby altering values used to calculate affinity constants. To prevent spurious interactions, we thoroughly clean the surface of the coverslip and then functionalize the glass either by applying a layer of silane or by coating with a lipid bilayer. PMID:27140911

  11. Absolute Position Total Internal Reflection Microscopy with an Optical Tweezer

    CERN Document Server

    Liu, Lulu; Rodriguez, Alejandro W; Capasso, Federico

    2014-01-01

    A non-invasive, in-situ calibration method for Total Internal Reflection Microscopy (TIRM) based on optical tweezing is presented which greatly expands the capabilities of this technique. We show that by making only simple modifications to the basic TIRM sensing setup and procedure, a probe particle's absolute position relative to a dielectric interface may be known with better than 10 nm precision out to a distance greater than 1 $\\mu$m from the surface. This represents an approximate 10x improvement in error and 3x improvement in measurement range over conventional TIRM methods. The technique's advantage is in the direct measurement of the probe particle's scattering intensity vs. height profile in-situ, rather than relying on calculations or inexact system analogs for calibration. To demonstrate the improved versatility of the TIRM method in terms of tunability, precision, and range, we show our results for the hindered near-wall diffusion coefficient for a spherical dielectric particle.

  12. Novel perspectives for the application of total internal reflection microscopy

    CERN Document Server

    Volpe, Giovanni; Helden, Laurent; Bechinger, Clemens

    2009-01-01

    Total Internal Reflection Microscopy (TIRM) is a sensitive non-invasive technique to measure the interaction potentials between a colloidal particle and a wall with femtonewton resolution. The equilibrium distribution of the particle-wall separation distance z is sampled monitoring the intensity I scattered by the Brownian particle under evanescent illumination. Central to the data analysis is the knowledge of the relation between I and the corresponding z, which typically must be known a priori. This poses considerable constraints to the experimental conditions where TIRM can be applied (short penetration depth of the evanescent wave, transparent surfaces). Here, we introduce a method to experimentally determine I(z) by relying only on the distance-dependent particle-wall hydrodynamic interactions. We demonstrate that this method largely extends the range of conditions accessible with TIRM, and even allows measurements on highly reflecting gold surfaces where multiple reflections lead to a complex I(z).

  13. Plasmonically amplified bioassay - Total internal reflection fluorescence vs. epifluorescence geometry.

    Science.gov (United States)

    Hageneder, Simone; Bauch, Martin; Dostalek, Jakub

    2016-08-15

    This paper investigates plasmonic amplification in two commonly used optical configurations for fluorescence readout of bioassays - epifluorescence (EPF) and total internal reflection fluorescence (TIRF). The plasmonic amplification in the EPF configuration was implemented by using crossed gold diffraction grating and Kretschmann geometry of attenuated total reflection method (ATR) was employed in the TIRF configuration. Identical assay, surface architecture for analyte capture, and optics for the excitation, collection and detection of emitted fluorescence light intensity were used in both TIRF and EPF configurations. Simulations predict that the crossed gold diffraction grating (EPF) can amplify the fluorescence signal by a factor of 10(2) by the combination of surface plasmon-enhanced excitation and directional surface plasmon-coupled emission in the red part of spectrum. This factor is about order of magnitude higher than that predicted for the Kretschmann geometry (TIRF) which only took advantage of the surface plasmon-enhanced excitation. When applied for the readout of sandwich interleukin 6 (IL-6) immunoassay, the plasmonically amplified EPF geometry designed for Alexa Fluor 647 labels offered 4-times higher fluorescence signal intensity compared to TIRF. Interestingly, both geometries allowed reaching the same detection limit of 0.4pM despite of the difference in the fluorescence signal enhancement. This is attributed to inherently lower background of fluorescence signal for TIRF geometry compared to that for EPF which compensates for the weaker fluorescence signal enhancement. The analysis of the inflammation biomarker IL-6 in serum at medically relevant concentrations and the utilization of plasmonic amplification for the fluorescence measurement of kinetics of surface affinity reactions are demonstrated for both EPF and TIRF readout. PMID:27260457

  14. Data Analysis for Total Internal Reflection Fluorescence Microscopy.

    Science.gov (United States)

    Asbury, Charles L

    2016-01-01

    In the microscopes we use to analyze total internal reflection fluorescence (TIRF), the emitted fluorescence is split chromatically, using dichroic filters, into either two or three different colors ("channels"). In our two-color instrument, the green emission wavelengths (405-488 nm; for imaging green fluorescent protein [GFP]-tagged proteins) and far-red emission wavelengths (650-800 nm; for imaging Alexa-647-labeled microtubules) are projected onto the upper and lower halves, respectively, of a single camera. A single filter can be swapped to collect near-red wavelengths (561-640 nm; for imaging mCherry, or Alexa-568-labeled microtubules) instead of far-red. Our three-color instrument is very similar except that the green, near-red, and far-red color ranges are projected onto three separate cameras. In either case, the different colors can be imaged simultaneously. Typically, we collect images at 10 frames/sec for ∼200 sec. We have developed a series of semiautomated image analysis programs, written in LabView, to obtain the brightness, residence time, and mobility of individual particles bound to single microtubules. The basic analysis steps are straightforward and could also be implemented using ImageJ or Matlab. For convenience, this protocol describes the analysis of a single microtubule. Data from many microtubules across many experimental trials are needed to obtain robust conclusions that are independent of stochastic and trial-to-trial variability. PMID:27140913

  15. Total internal reflection and dynamic light scattering microscopy of gels

    Science.gov (United States)

    Gregor, Brian F.

    Two different techniques which apply optical microscopy in novel ways to the study of biological systems and materials were built and applied to several samples. The first is a system for adapting the well-known technique of dynamic light scattering (DLS) to an optical microscope. This can detect and scatter light from very small volumes, as compared to standard DLS which studies light scattering from volumes 1000x larger. The small scattering volume also allows for the observation of nonergodic dynamics in appropriate samples. Porcine gastric mucin (PGM) forms a gel at low pH which lines the epithelial cell layer and acts as a protective barrier against the acidic stomach environment. The dynamics and microscopic viscosity of PGM at different pH levels is studied using polystyrene microspheres as tracer particles. The microscopic viscosity and microrheological properties of the commercial basement membrane Matrigel are also studied with this instrument. Matrigel is frequently used to culture cells and its properties remain poorly determined. Well-characterized and purely synthetic Matrigel substitutes will need to have the correct rheological and morphological characteristics. The second instrument designed and built is a microscope which uses an interferometry technique to achieve an improvement in resolution 2.5x better in one dimension than the Abbe diffraction limit. The technique is based upon the interference of the evanescent field generated on the surface of a prism by a laser in a total internal reflection geometry. The enhanced resolution is demonstrated with fluorescent samples. Additionally. Raman imaging microscopy is demonstrated using the evanescent field in resonant and non-resonant samples, although attempts at applying the enhanced resolution technique to the Raman images were ultimately unsuccessful. Applications of this instrument include high resolution imaging of cell membranes and macroscopic structures in gels and proteins. Finally, a third

  16. Dual economies and international total factor productivity differences

    DEFF Research Database (Denmark)

    Chanda, Areendam; Dalgaard, Carl-Johan Lars

    2008-01-01

    This paper provides a framework that decomposes aggregate total factor productivity (TFP) into a component reflecting relative efficiency across sectors, and another component that reflects the absolute level of efficiency. A development accounting analysis suggests that as much as 85% of the...

  17. A visual classroom demonstration of frustrated total internal reflection as an analogue to optical tunnelling

    Science.gov (United States)

    Salman, Rabiya; Rashid, Shama; Sabieh Anwar, Muhammad

    2013-11-01

    Frustrated total internal reflection is presented as a visually attractive and convenient classroom demonstration. Optical evanescent waves penetrating through a dielectric barrier is a classical analogue to quantum mechanical tunnelling. We use the traditional double prism arrangement to demonstrate the pickup and relaunching of the evanescent wave. Total internal reflection could be completely frustrated by the insertion of an index matching fluid.

  18. Rapid determination of total trans fat content--an attenuated total reflection infrared spectroscopy international collaborative study.

    Science.gov (United States)

    Mossoba, M M; Adam, M; Lee, T; Bastyr, J

    2001-01-01

    Interest in trans fat labeling has prompted efforts to develop new, more efficient methods for rapidly and accurately determining trans fat content of foods. A novel and rapid (5 min) attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopic procedure was recently developed and applied to food products. This procedure was voted official method AOCS Cd 14d-99 by the American Oil Chemists' Society in 1999 after testing in a 12 laboratory international collaborative study. The results of the study are described in this paper. Analytical ATR-FTIR results exhibited high accuracy in the range 5-40% trans; results tended to have internal reflection method was found to be superior to the precision of transmission infrared official methods. It is recommended that the applicability of the ATR-FTIR method be limited to trans levels of >5% (as percent of total fat). PMID:11501916

  19. CT image evaluation of the internal rotation limit prior to bony impingement after total hip arthroplasty

    International Nuclear Information System (INIS)

    This study evaluated the internal rotation limit prior to bony impingement of the proximal femur on the pelvis after total hip arthroplasty (THA). Reconstructed computed tomography (CT) images of 90 deg hip flexion were used to simulate the internal rotation limit against safety limits measured intraoperatively. Ninety joints in 86 subjects (12 men and 74 women) underwent THA for the treatment of secondary coxarthrosis. The correlation between the internal rotation limit prior to the bony impingement intraoperatively and the simulated internal rotation angle on the reconstructed CT image was statistically significant. We provide a new method to simulate the internal rotation limit prior to bony impingement based on postoperative CT. (author)

  20. Reliability and Validity of the Dutch Version of the International Physical Activity Questionnaire in Patients After Total Hip Arthroplasty or Total Knee Arthroplasty

    NARCIS (Netherlands)

    Blikman, Tim; Stevens, Martin; Bulstra, Sjoerd K.; van den Akker-Scheek, Inge; Reininga, Inge H. F.

    2013-01-01

    STUDY DESIGN: Psychometric assessment. OBJECTIVES: To determine test-retest reliability and concurrent validity of the International Physical Activity Questionnaire (IPAQ) in patients after total hip arthroplasty or total knee arthroplasty. BACKGROUND: Despite recognized benefits of regular physical

  1. Optical Waveguide Switches Employing Total-Internal-Reflection (TIR) Effect (Invited Paper)

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    In this paper, our recent research work on the total-internal-reflection optical switch is presented. The thermo-optic effect of polymeric materials and the photon-induced carrier effect of GaAlAs/GaAs are used in our devices.

  2. Total internal reflection fluorescence microscopy imaging-guided confocal single-molecule fluorescence spectroscopy

    OpenAIRE

    Zheng, Desheng; Kaldaras, Leonora; Lu, H. Peter

    2012-01-01

    We have developed an integrated spectroscopy system combining total internal reflection fluorescence microscopy imaging with confocal single-molecule fluorescence spectroscopy for two-dimensional interfaces. This spectroscopy approach is capable of both multiple molecules simultaneously sampling and in situ confocal fluorescence dynamics analyses of individual molecules of interest. We have demonstrated the calibration with fluorescent microspheres, and carried out single-molecule spectroscop...

  3. Internal Consistency and Power When Comparing Total Scores from Two Groups.

    Science.gov (United States)

    Barchard, Kimberly A; Brouwers, Vincent

    2016-01-01

    Researchers now know that when theoretical reliability increases, power can increase, decrease, or stay the same. However, no analytic research has examined the relationship of power to the most commonly used type of reliability-internal consistency-and the most commonly used measures of internal consistency, coefficient alpha and ICC(A,k). We examine the relationship between the power of independent samples t tests and internal consistency. We explicate the mathematical model upon which researchers usually calculate internal consistency, one in which total scores are calculated as the sum of observed scores on K measures. Using this model, we derive a new formula for effect size to show that power and internal consistency are influenced by many of the same parameters but not always in the same direction. Changing an experiment in one way (e.g., lengthening the measure) is likely to influence multiple parameters simultaneously; thus, there are no simple relationships between such changes and internal consistency or power. If researchers revise measures to increase internal consistency, this might not increase power. To increase power, researchers should increase sample size, select measures that assess areas where group differences are largest, and use more powerful statistical procedures (e.g., ANCOVA). PMID:27269041

  4. Magneto-optical effects in multilayers illuminated by total internal reflection

    Science.gov (United States)

    Richard, N.; Dereux, A.; David, T.; Bourillot, E.; Goudonnet, J. P.; Scheurer, F.; Beaurepaire, E.; Garreau, G.

    1999-02-01

    This paper describes the magneto-optical effects of metallic multilayers under the condition of total internal reflection. In the framework of Green's dyadic technique, we detail a practical and at time-consuming scheme to compute accurately the optical properties of anisotropic multilayers deposited on a substrate. We present numerical simulations which account for the variation of the angle of incidence at a fixed wavelength and for the variation of the wavelength at fixed angle of incidence. The Kerr rotation is found to increase significantly around the critical angle for total reflection. We also discuss the importance of plasmon effects in the structure of the Kerr rotation spectra.

  5. Frustrated Total Internal Reflection: Resonant and Negative Goos-H\\"anchen Shifts in Microwave Regime

    CERN Document Server

    Qu, Min

    2010-01-01

    It is well-known that the variations of Goos-H\\"anchen shifts (GHSs) are closely associated with the enengy-flux provided by evanescent states in the case of total internal reflection. However, when the frustrated internal total reflection (FTIR) is realized with a Polymethyl Methacrylate (PMMA) double-prism system operated in the microwave frequency range of 8.2 GHz to 12.4 GHz, we observe that the GH shifts for the reflected beam show periodic resonances with varying the operation frequency or the air layer thickness, which is different from the variation of the corresponding reflected energy. Moreover, in another FTIR based system introduced by a composite absorptive material slab with a two-dimensional top layer of frequency selective surface (FSS), the GHSs for reflected beam are discovered as not only resonant but also negative with the incidence of transverse electric that is TE polarized.

  6. Design of plasmonic nano-antenna for total internal reflection fluorescence microscopy.

    Science.gov (United States)

    Lee, Eun-Khwang; Song, Jung-Hwan; Jeong, Kwang-Yong; Seo, Min-Kyo

    2013-10-01

    We propose a gold modified bow-tie plasmonic nano-antenna, which can be suitably used in combination with total internal reflection fluorescence microscopy. The plasmonic nano-antenna, supporting well-separated multiple resonances, not only concentrates the total internal reflection evanescent field at the deep subwavelength scale, but also enhances fluorescence emission by the Purcell effect. Finite-difference time-domain computations show that the enhancement of the excitation light strongly correlates with the far-field radiation pattern radiated from the antenna. Depending on the antenna geometry, the resonant modes are widely tuned and their wavelengths can be easily matched to the diverse emission or excitation wavelengths of fluorophores. PMID:24104219

  7. MODALITY OF DETERMINING THE TOTAL SCORE OF RISKS IN INTERNAL AUDIT

    Directory of Open Access Journals (Sweden)

    FRANCA DUMITRU

    2012-11-01

    Full Text Available Risk analysis materializes in: applying to the weightings of risk factors the level of risk assessment, on risk factors, based on the assessments made by auditors regarding: the functionality of internal control, the influence of quantitative and qualitative elements; determination of the total risk score, which represents a sum of weights between the appreciation level of each risk and the weightings of risk factors.

  8. Investigation And Application Of The Frustrated-Total-Internal-Reflection Phenomenon in Optical Fibers

    OpenAIRE

    Rahnavardy, K.; Arya, Vivek; Wang, A.; Weiss, J.M.

    1997-01-01

    A detailed investigation of the frustrated-total-internal-reflection (FTIR) phenomenon in silica-glass-based optical fibers and its application to simple intensity-modulated strain and pressure sensors is presented. Such sensors may be readily fabricated with silica-based fibers and can be easily modified with sapphire fibers for high-temperature industrial applications where conventional silica-based fiber sensors are not feasible. We present the all-fiber FTIR sensor and show good correlati...

  9. Variable-angle total internal reflection fluorescence microscopy of intact cells of Arabidopsis thaliana

    OpenAIRE

    Kim Myung K; Hao Huaiqin; Fan Lusheng; Ash William M; Wan Yinglang; Lin Jinxing

    2011-01-01

    Abstract Background Total internal reflection fluorescence microscopy (TIRFM) is a powerful tool for observing fluorescently labeled molecules on the plasma membrane surface of animal cells. However, the utility of TIRFM in plant cell studies has been limited by the fact that plants have cell walls, thick peripheral layers surrounding the plasma membrane. Recently, a new technique known as variable-angle epifluorescence microscopy (VAEM) was developed to circumvent this problem. However, the ...

  10. Efficient optical path folding by using multiple total internal reflections in a microcavity

    CERN Document Server

    Shinohara, Susumu; Fukushima, Takehiro; Harayama, Takahisa; Arai, Kenichi; Yoshimura, Kazuyuki

    2014-01-01

    We propose using an asymmetric resonant microcavity for the efficient generation of an optical path that is much longer than the diameter of the cavity. The path is formed along a star polygonal periodic orbit within the cavity, which is stable and confined by total internal reflection. We fabricated a semiconductor device based on this idea with an average diameter of 0.3 mm, and achieved a path length of 2.79 mm experimentally.

  11. Proceedings of RITE international workshop on valuation; Total eko balance ni kansuru kokusai workshop hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The RITE International Workshop on Valuation was held in Tokyo and Osaka in February 1996, and eight papers on total ecobalance were reported. In The Field of Impact Assessment, described were constitution and methodology about impact assessment in a wide sense. In LCA Yesterday, Today and Tomorrow, discussed were the historical development and future outlook of LCA. In Standardization of Product Life Cycle Assessment, a survey of the present situation of LCA international standardization was made. In the Relationship between Product Life Cycle Assessment Methodology, considered was the relationship between the goal definition of the product life cycle assessment and the methodological choices. In Valuation in LCA, the present study of LCA was reviewed. Besides, reviews of the LCA study in Japan were made public.

  12. Theory of frustrated total internal reflection: Superluminal singularities of optical waveguides

    International Nuclear Information System (INIS)

    Classical approach to frustrated total internal reflection (FTIR) does not describe its temporal properties, that are additionally considered and their superluminal singularity is shown. The transition to quantum electrodynamics shows that momenta of photons are reduced at FTIR relative to energy, i.e. it is the tunnel process, the nonlocal manifestation of near field. The tunneling consists in the instantaneous jump of excitations (virtual photons) onto definite distance, and can be described by equation having certain instanton features. Thus, the possibility of signal transfer with superluminal group velocity via optical fibers is substantiated that conforms to certain supervisions. Such properties of FTIR near field may explain, in principle, some other observed phenomena

  13. Study of the interaction between HSA and oligo-DNA using total internal reflection ellipsometry

    Science.gov (United States)

    Jung, Y. W.; Byun, J. S.; Kim, Y. D.; Hemzal, D.; Humliček, J.

    2012-04-01

    Techniques of quantitative analysis are very important for studies of the interactions between bio-molecules in the field of biotechnology and drug development. The total internal reflection ellipsometry system (TIRE) is an attractive label-free procedure for the quantitative analysis of biomolecules because it combines the analytic ability of ellipsometry and the high surface sensitivity of surface plasmon resonance. In this work, we have used TIRE to study the optical properties of an aquatic monolayer of human serum albumin (HSA) and oligo-DNA. Also, we have monitored the adsorption and the interaction processes of protein layers.

  14. Integrated optic polarization splitter based on total internal reflection from a birefringent polymer.

    Science.gov (United States)

    Huang, Guanghao; Park, Tae-Hyun; Chu, Woo-Sung; Oh, Min-Cheol

    2016-09-01

    An integrated optic polarization splitter with large fabrication tolerance and high reliability is required for optical signal processing in quantum-encrypted communication systems. A polarization splitter based on total internal reflection from a highly birefringent polymer-reactive mesogen-is proposed and demonstrated in this work. The device consists of a mode expander for reducing the wave vector distribution of the guided mode, and an interface with a large birefringence. Several polymers with suitable refractive indexes were used for fabricating the device. We obtained a polarization splitter with a low crosstalk (less than -30 dB), and a large fabrication tolerance. PMID:27607704

  15. Microplate-compatible total internal reflection fluorescence microscopy for receptor pharmacology

    Science.gov (United States)

    Chen, Minghan; Zaytseva, Natalya V.; Wu, Qi; Li, Min; Fang, Ye

    2013-05-01

    We report the use of total internal reflection fluorescence (TIRF) microscopy for analyzing receptor pharmacology and the development of a microplate-compatible TIRF imaging system. Using stably expressed green fluorescence protein tagged β2-adrenergic receptor as the reporter, we found that the activation of different receptors results in distinct kinetic signatures of the TIRF intensity of cells. These TIRF signatures closely resemble the characteristics of their respective label-free dynamic mass redistribution signals in the same cells. This suggests that TIRF in microplate can be used for profiling and screening drugs.

  16. Frustrated total internal reflection and critical coupling in a thick plasmonic grating with narrow slits

    International Nuclear Information System (INIS)

    We demonstrate the possibility of critical coupling through frustrated total internal reflection in a thick plasmonic grating below the first diffraction order. Differently from conventional approaches relying on the excitation of surface plasmon-polaritons, here we exploit the light coupling with the leaky modes supported by the grating. This mechanism entails a wide-angle coupling and effectively access spectral bands that would otherwise be difficult to probe using conventional plasmonic critical coupling techniques, such as the Otto configuration. Our finding may pave the way to efficient plasmonic bio-sensor devices.

  17. Dynamical measurement of refractive index distribution using digital holographic interferometry based on total internal reflection.

    Science.gov (United States)

    Zhang, Jiwei; Di, Jianglei; Li, Ying; Xi, Teli; Zhao, Jianlin

    2015-10-19

    We present a method for dynamically measuring the refractive index distribution in a large range based on the combination of digital holographic interferometry and total internal reflection. A series of holograms, carrying the index information of mixed liquids adhered on a total reflection prism surface, are recorded with CCD during the diffusion process. Phase shift differences of the reflected light are reconstructed exploiting the principle of double-exposure holographic interferometry. According to the relationship between the reflection phase shift difference and the liquid index, two dimensional index distributions can be directly figured out, assuming that the index of air near the prism surface is constant. The proposed method can also be applied to measure the index of solid media and monitor the index variation during some chemical reaction processes. PMID:26480394

  18. Variable-angle total internal reflection fluorescence microscopy of intact cells of Arabidopsis thaliana

    Directory of Open Access Journals (Sweden)

    Kim Myung K

    2011-09-01

    Full Text Available Abstract Background Total internal reflection fluorescence microscopy (TIRFM is a powerful tool for observing fluorescently labeled molecules on the plasma membrane surface of animal cells. However, the utility of TIRFM in plant cell studies has been limited by the fact that plants have cell walls, thick peripheral layers surrounding the plasma membrane. Recently, a new technique known as variable-angle epifluorescence microscopy (VAEM was developed to circumvent this problem. However, the lack of a detailed analysis of the optical principles underlying VAEM has limited its applications in plant-cell biology. Results Here, we present theoretical and experimental evidence supporting the use of variable-angle TIRFM in observations of intact plant cells. We show that when total internal reflection occurs at the cell wall/cytosol interface with an appropriate angle of incidence, an evanescent wave field of constant depth is produced inside the cytosol. Results of experimental TIRFM observations of the dynamic behaviors of phototropin 1 (a membrane receptor protein and clathrin light chain (a vesicle coat protein support our theoretical analysis. Conclusions These findings demonstrate that variable-angle TIRFM is appropriate for quantitative live imaging of cells in intact tissues of Arabidopsis thaliana.

  19. Small-Angle Measurement of Laser Beam Steering Based on Total Internal-Reflection Effect

    International Nuclear Information System (INIS)

    A precision small-angle measurement system is introduced based on optical total internal reflection effect. When the incident angle of a polarized beam is larger than the critical angle, and the beam has a small steering angle in the vicinity of the critical angle, the total internal reflection will take place and a relative phased shift between the s- and the p-polarized components is produced. By utilizing the characteristics we could measure the small angle displacement of the incident beam. A differential optical system including four right-angle prisms is set up based on above, and we take the difference of the interference intensity of sand p-components divided by their sum as the output signal. A good linearity between the output signal and the angular displacement is proved by the theoretical simulation. The system result and error analysis are given as well. The experiment shows that the measurement range of this system is ±20, and a resolution of 10'' is achieved. This method has many advantages, such as simple configuration, high sensitivity, good linearity and high antinoise ability

  20. Smooth and rough Proteus mirabilis lipopolysaccharides studied by total internal reflection ellipsometry

    Energy Technology Data Exchange (ETDEWEB)

    Gleńska-Olender, J., E-mail: joannaglenska@wp.pl [Institute of Biology, Jan Kochanowski University, 25-406 Kielce (Poland); Świętokrzyski Biobank, Regional Science and Technology Center, 26-060 Chęciny (Poland); Dworecki, K. [Institute of Physics, Jan Kochanowski University, 25-406 Kielce (Poland); Sęk, S. [Department of Chemistry, University of Warsaw, 02-093 Warsaw (Poland); Kwinkowski, M.; Kaca, W. [Institute of Biology, Jan Kochanowski University, 25-406 Kielce (Poland)

    2013-12-02

    Total internal reflection ellipsometry (TIRE), a label-free optical detection technique for studying interactions between biomolecules, was used to examine the adsorption of various forms of lipopolysaccharides (LPSs) isolated from Proteus mirabilis S1959, R110, and R45 strains on a gold surface. The thickness of the adsorbed layers was determined by TIRE, with the average values for S1959, R110, and R45 LPS layers being 78 ± 5, 39 ± 3, and 12 ± 2 nm, respectively. The thickness of LPS layers corresponds to the presence and length of O-specific parts in P. mirabilis LPS molecules. Atomic force microscopy was used as a complementary technique for visualizing lipopolysaccharides on the surface. Force measurements seem to confirm the data obtained from TIRE experiments. - Highlights: • Proteus mirabilis lipopolysaccharides were adsorbed on the gold surface. • Thickness of adsorbed layers was determined by total internal reflection ellipsometry. • Atomic force microscopy was used to visualize lipopolysaccharide build-up on gold surface. • Time is important in the evolution of biomolecular film thickness created on gold surface.

  1. Smooth and rough Proteus mirabilis lipopolysaccharides studied by total internal reflection ellipsometry

    International Nuclear Information System (INIS)

    Total internal reflection ellipsometry (TIRE), a label-free optical detection technique for studying interactions between biomolecules, was used to examine the adsorption of various forms of lipopolysaccharides (LPSs) isolated from Proteus mirabilis S1959, R110, and R45 strains on a gold surface. The thickness of the adsorbed layers was determined by TIRE, with the average values for S1959, R110, and R45 LPS layers being 78 ± 5, 39 ± 3, and 12 ± 2 nm, respectively. The thickness of LPS layers corresponds to the presence and length of O-specific parts in P. mirabilis LPS molecules. Atomic force microscopy was used as a complementary technique for visualizing lipopolysaccharides on the surface. Force measurements seem to confirm the data obtained from TIRE experiments. - Highlights: • Proteus mirabilis lipopolysaccharides were adsorbed on the gold surface. • Thickness of adsorbed layers was determined by total internal reflection ellipsometry. • Atomic force microscopy was used to visualize lipopolysaccharide build-up on gold surface. • Time is important in the evolution of biomolecular film thickness created on gold surface

  2. International investigation into the relationship between social expenditure for family and total fertility rate.

    Science.gov (United States)

    Motoki, Airi; Shinohara, Ryoji; Yamagata, Zentaro

    2016-01-01

    Purpose Declining birth rates are an important social issue worldwide, and allocating resources to benefits for child-rearing households is a necessary countermeasure. In this study, we investigate and compare the relationship between child-related social security costs and total fertility rate internationally.Method In 2011, the ratios of family- and elderly-related social spending to gross domestic product (GDP) were recorded in 34 Organisation for Economic Co-operation and Development (OECD) member countries. The former was designated as the percentage allocated to members of the population between the ages of 0 and 14 (young population ratio), and the latter was designated as the percentage allocated to members of the population over the age of 65 (elderly population ratio). We compared these two factors for every country and performed correlation and partial correlation analyses of total fertility rates and family-related social spending to GDP adjusted by population proportion to examine the relationship between the two.Results The comparison of the youth and elderly populations' spending ratios in the total social spending to GDP ratio revealed that OECD countries had an average family-related social spending ratio of 0.13 and an average elderly-related social spending ratio of 0.47. Comparatively, Japan has a family-related social spending ratio of 0.10 and an elderly-related social spending ratio of 0.45. In the correlation analysis for total fertility rates and family-related social spending to GDP ratio, the benefits-in-kind to GDP ratio and total fertility rates indicated a trend toward correlation (r=0.32, P=0.06). In addition, the results for the partial correlation between family-related social spending to GDP ratio and total fertility rates showed a significant correlation between the two. When divided into cash benefits and benefits-in-kind, the partial correlation analysis of the GDP ratios and total fertility rates revealed a significant

  3. Novel Propagation Properties of Total Internal Reflection Photonic Crystal Fibres with Rhombic Air Holes

    Institute of Scientific and Technical Information of China (English)

    YAN Hai-Feng; YU Zhong-Yuan; LIU Yu-Min; TIAN Hong-Da; HAN Li-Hong

    2011-01-01

    We investigate the propagation properties of a multi-layer photonic crystal fiber with novel rhombic air holes using the finite element method,and calculate the dependence of the propagation properties on the wavelength in the fiber with different geometrical structural parameters,including the internal angle and the external arrangement of the rhombic air holes.Optimizing these parameters,we design a photonic crystal which exhibits both a small dispersion value and low loss near the wavelength of 1.55 μm.Photonic crystal fibers are known as microstructured optical fibers or multi-hole optical fibers,and their cross sections have periodic structures with hollows in the centers due to one or more missing air holes as shown in Fig.1.The light wave can propagate along this hollow structure,which can be considered as the core of the fiber.According to the light-guiding mechanism,there are two types of photonic crystal fibers:total internal reflection photonic crystal fibers and photonic bandgap photonic crystal fibers.[1] The propagation properties of total internal reflection photonic crystal fibers are determined by the arrangements of holes in the transverse field.[1,2] With the flexibility to control the arrangement,size and shape of the air holes,various photonic crystal fibers with different optical properties can be designed as desired.Recently the microstructural design of photonic crystal fibers has drawn extensive attention over the world.[3] As a novel kind of optical fiber,photonic crystal fibers have been widely used for optoelectronic devices.%We investigate the propagation properties of a multi-layer photonic crystal fiber with novel rhombic air holes using the finite element method, and calculate the dependence of the propagation properties on the wavelength in the fiber with different geometrical structural parameters, including the internal angle and the external arrangement of the rhombic air holes. Optimizing these parameters, we design a photonic

  4. Redistribution of fluorescent molecules at the solid/liquid interface with total internal reflection illumination.

    Science.gov (United States)

    Wei, Lin; Ye, Zhongju; Luo, Wenjuan; Chen, Bo; Xiao, Lehui

    2016-08-01

    Many intriguing physical and chemical processes commonly take place at the solid/liquid interface. Total internal reflection illumination, together with single molecule spectroscopy, provides a robust platform for the selective exploration of kinetic processes close the interface. With these techniques, it was observed that the distribution of Rhodamine B molecules close to a solid/liquid interface could be regulated in a photo-induced route. The laser-induced repulsion force at this interface is enough to compromise the Brownian diffusion of single molecules in a range of several hundred nanometers normal to the solid/liquid interface. This observation is fundamentally and practically interesting because moderate laser intensity is enough to initiate this repulsion effect. Therefore, it might display extensive applications in the development of photo-modulation technique with high throughput capability. PMID:27216678

  5. Goos-H\\"anchen shifts in frustrated total internal reflection studied with wave packet propagation

    CERN Document Server

    Chen, Xi; Wei, Rong-Rong; Zhang, Yan

    2009-01-01

    We have investigated that the Goos-H\\"anchen (GH) shifts in frustrated total internal reflection (FTIR) studied with wave packet propagation. In the first-order approximation of the transmission coefficient, the GH shift is exactly the expression given by stationary phase method, thus saturates an asymptotic constant in two different ways depending on the angle of incidence. Taking account into the second-order approximation, the GH shift always depends on the width of the air gap due to the modification of the beam width. It is further shown that the GH shift with second-order correction increases with decreasing the beam width at the small incidence angles, while for the large incidence angles it reveals a strong decrease with decreasing the beam width. These phenomena offers the better understanding of the tunneling delay time in FTIR.

  6. Watch your step! A frustrated total internal reflection approach to forensic footwear imaging

    Science.gov (United States)

    Needham, J. A.; Sharp, J. S.

    2016-02-01

    Forensic image retrieval and processing are vital tools in the fight against crime e.g. during fingerprint capture. However, despite recent advances in machine vision technology and image processing techniques (and contrary to the claims of popular fiction) forensic image retrieval is still widely being performed using outdated practices involving inkpads and paper. Ongoing changes in government policy, increasing crime rates and the reduction of forensic service budgets increasingly require that evidence be gathered and processed more rapidly and efficiently. A consequence of this is that new, low-cost imaging technologies are required to simultaneously increase the quality and throughput of the processing of evidence. This is particularly true in the burgeoning field of forensic footwear analysis, where images of shoe prints are being used to link individuals to crime scenes. Here we describe one such approach based upon frustrated total internal reflection imaging that can be used to acquire images of regions where shoes contact rigid surfaces.

  7. Observation of Insulin Exocytosis by a Pancreatic (3 Cell Line with Total Internal Reflection Fluorescence Microscopy

    Institute of Scientific and Technical Information of China (English)

    Zhao-ying Fu; Ya-ping Wang; Yu Chen

    2011-01-01

    @@ INSULIN secretion was traditionally measured with biochemical and immunological methods such as enzyme linked immunosorbant assay and radio-immunoassay.However,these methods can only tell the amount of insulin secreted; they give no information about the secretion process or mechanism of exocytosis.In recent years,an imaging technique known as total internal reflection fluorescence (TIRF) microscopy has been employed to study insulin secretion.1-4 This imaging technique can explore events taking place near or on live cell membrane,such as secretory granule movement,exocytosis,vesicle content release,and membrane fusion.5-10 In the present paper,we applied TIRF microscopy to the observation of insulin exocytosis by the pancreatic β cell line Ins-1.

  8. Super hydrophobic surface of polytetrafluoroethylene fabricated by picosecond laser and phenomenon of total internal reflection underwater

    Science.gov (United States)

    Jiang, Yijian; Cao, Wenshen; Zhao, Yan; Wu, Yan; Ji, Lingfei

    2015-03-01

    A groove-shaped array with average 25 μm interval, 25 μm wall thickness, 75 μm depth and a columnar array with average 30 μm side length, 25 μm interval, 43 μm depth are processed by 1064 nm picosecond laser on polytetrafluoroethylene (PTFE) surface at room temperature. The water contact angle of modified PTFE surface can reach 167°, which show super hydrophobic surface of PTFE is prepared. It is observed super hydrophobic surface reflects metal luster underwater through the glassware when super hydrophobic PTFE entirely immerses in pure water. The experiment conducts super hydrophobic surface will enhance intensity of reflection of visible light underwater, which is due to total internal reflection of super hydrophobic surface und erwater.

  9. Calibration method for measurement of linear nanometric distances by scattered total internal reflection

    International Nuclear Information System (INIS)

    Scattered total internal reflection of visible light is used to measure linear nanometric distance to as small as 10 nm. Specifically, we measure the height of magnetic transducer heads above a rotating glass disk. A breakthrough in the approach to calibration, based on combining the second derivative of the transmittance of the scattered light and parameter fitting, substantially improves the quality of the measurement relative to previous demonstrations of this method. The results agree to 1 nm with an industry-standard three-color interferometer to and including the lowest values measured. The technique in principle remains robust to as low as the zero height. Furthermore the calibration point can be as low as 10 nm, which is especially attractive in practice

  10. Nanoscale characterization of vesicle adhesion by normalized total internal reflection fluorescence microscopy.

    Science.gov (United States)

    Cardoso Dos Santos, Marcelina; Vézy, Cyrille; Jaffiol, Rodolphe

    2016-06-01

    We recently proposed a straightforward fluorescence microscopy technique to study adhesion of Giant Unilamellar Vesicles. This technique is based on dual observations which combine epi-fluorescence microscopy and total internal reflection fluorescence (TIRF) microscopy: TIRF images are normalized by epi-fluorescence ones. By this way, it is possible to map the membrane/substrate separation distance with a nanometric resolution, typically ~20nm, with a maximal working range of 300-400nm. The purpose of this paper is to demonstrate that this technique is useful to quantify vesicle adhesion from ultra-weak to strong membrane-surface interactions. Thus, we have examined unspecific and specific adhesion conditions. Concerning unspecific adhesion, we have controlled the strength of electrostatic forces between negatively charged vesicles and various functionalized surfaces which exhibit a positive or a negative effective charge. Specific adhesion was highlighted with lock-and-key forces mediated by the well defined biotin/streptavidin recognition. PMID:26972045

  11. Total-internal-reflection-based photomask for large-area photolithography

    Science.gov (United States)

    Hung, Shao-Kang; Lin, Kung-Hsuan; Chen, Cheng-Lung; Chou, Chen-Hsun; Lin, You-Chuan

    2016-05-01

    Photolithography has been widely implemented with a photomask in contact or in close proximity to the photoresist layer. The flatness of the substrates is a crucial factor to guarantee the quality of the entire patterned photoresist (PR) layer especially for large-area photolithography. However, some substrates, such as sapphire wafers, do not possess highly uniform thickness as silicon wafer does. In this work, we demonstrate that a flexible polydimethylsiloxane (PDMS) photomask with optical total-internal-reflection structure can effectively circumvent this problem for mass production. Different from conventional photomask that the light is blocked by the patterned reflective/absorbing materials, the distributions of light intensity on the PR is engineered by the geometric structure of the transparent PDMS photomask. We demonstrate that 4 in. patterned sapphire wafers can be successfully fabricated by using this PDMS photomask, which can be easily integrated into the present techniques in industry for mass production of substrates for GaN-based optoelectronic devices.

  12. Total-Internal-Reflection Platforms for Chemical and Biological Sensing Applications

    Science.gov (United States)

    Sapsford, Kim E.

    Sensing platforms based on the principle of total internal reflection (TIR) represent a fairly mature yet still expanding and exciting field of research. Sensor development has mainly been driven by the need for rapid, stand-alone, automated devices for application in the fields of clinical diagnosis and screening, food and water safety, environmental monitoring, and chemical and biological warfare agent detection. The technologies highlighted in this chapter are continually evolving, taking advantage of emerging advances in microfabrication, lab-on-a-chip, excitation, and detection techniques. This chapter describes many of the underlying principles of TIR-based sensing platforms and additionally focusses on planar TIR fluorescence (TIRF)-based chemical and biological sensors.

  13. Development of the Second Generation International Space Station (ISS) Total Organic Carbon Analyzer (TOCA)

    Science.gov (United States)

    Clements, Anna L.; Stinson, Richard G.; VanWie, Michael; Warren, Eric

    2009-01-01

    The second generation International Space Station (ISS) Total Organic Carbon Analyzer s (TOCA) function is to monitor concentrations of Total Organic Carbon (TOC) in ISS water samples. TOC is one measurement that provides a general indication of overall water quality by indicating the potential presence of hazardous chemicals. The data generated from the TOCA is used as a hazard control to assess the quality of the reclaimed and stored water supplies on-orbit and their suitability for crew consumption. This paper details the unique ISS Program requirements, the design of the ISS TOCA, and a brief description of the on-orbit concept-of-operations. The TOCA schematic will be discussed in detail along with specific information regarding key components. The ISS TOCA was designed as a non-toxic TOC analyzer that could be deployed in a flight ready package. This basic concept was developed through laboratory component level testing, two moderate fidelity integrated system breadboard prototypes, a flight-like full scale prototype, as well as lessons learned from the inadequacies of the first unit. The result: a new TOCA unit that is robust in design and includes special considerations to microgravity and the on-orbit ISS environment. TOCA meets the accuracy needs of the ISS Program with a 1,000 to 25,000 g/L range, accurate to within +/-25%.

  14. Optical absorption under total internal reflection in the characterization of soot in diesel engine oils

    International Nuclear Information System (INIS)

    Optical absorption of infrared radiation under total internal reflection in a novel sensor has been utilized to investigate the soot contamination of diesel engine oil by response surface methodology in factorial experiments. Sensor response showed highly significant dependence on oil soot concentration and temperature, in which the effect of the soot was greatest. The soot contamination of the optical rod in engine oil was found to be a surface phenomenon which showed little or no dependence on bulk oil shearing displacement below 500 rpm. The quadratic effect of sensor response to soot concentration was very high due to the agglomeration of soot particles, derived from the high surface energy of carbon soot. Test results of this optical absorption technique were in conformance with those other oil analysis techniques such as UV spectrophotometry, total acid number, viscosimetry, optical microscopy and EPMA. The technique proved to be more reliable than RDE emission spectrometry which showed ambiguous results due to colloidal suspension of soot particles in oil. Optical absorption proved to be an effective criterion in characterizing the soot contamination of diesel engine oil

  15. Outcome of total hip arthroplasty as a salvage procedure for failed infected internal fixation of hip fractures

    OpenAIRE

    Shubhranshu S Mohanty; Agashe, Mandar V.; Sheth, Binoti A; Kumar K. Dash

    2013-01-01

    Background: Failed infected internal fixation produces significant pain and functional disability. In infected internal fixation of hip fractures with partial or complete head destruction, total hip arthroplasty (THA) can be technically challenging; however, it restores hip biomechanics. The present study is to evaluate the results and assess the complications of THA following failed infected internal fixation of these fractures. Materials and Methods: A retrospective review of prospectiv...

  16. The Total System Performance Assessment/Site Recommendation. International Peer Review

    International Nuclear Information System (INIS)

    Abe van Luik (US DOE-YM, USA) presented the preliminary results of the Yucca Mountain international peer review of the Total System performance Assessments (TSPA) and a few preliminary indications of the issues. The peer review by 10 experts was organised by a joint secretariat formed by the NEA and the IAEA. Two meetings and three exchanges of questions and answers by E-mail between the meetings provided preliminary results that were orally presented at the end of August. The final report is due to the DOE by the end of January 2002. Abe Van Luik presented some unofficial examples of preliminary observations. As an example, he mentioned the reviewers' observation that uncertainties need an overall strategy for their evaluation and reduction. It was also mentioned that the documentation is not yet sufficiently transparent. An important issue for the review team was the ability to compare the safety evaluations of different nations' potential repositories. Finally, the reviewers made it clear that although the applicable regulation for this phase had been competently addressed, the documentation was not a safety case. Several shortcomings kept it from being a safety case, noteworthy being the lack of a statement on confidence, and a description of the basis of that confidence

  17. Visualizing substructure of Ca2+ waves by total internal reflection fluorescence microscopy

    Science.gov (United States)

    Bai, Yongqiang; Tang, Aihui; Wang, Shiqiang; Zhu, Xing

    2005-02-01

    Total internal reflection fluorescence microscope is a new optical microscopic system based on near-field optical theory. Its character of illumination by evanescent wave, together with the great signal-to-noise ratio and temporal resolution achieved by high quality CCD, allows us to analyze the spatiotemporal details of local Ca2+ dynamics within the nanoscale microdomain surrounding different Ca2+ channels. We have recently constructed a versatile objective TIRFM equipped with a high numerical aperture (NA=1.45) objective. Using fluo-4 as the Ca2+ indicator, we visualized the near-membrane profiles of Ca2+ waves and elementary Ca2+ sparks generated by Ca2+ release channels in rat ventricular myocytes. Different from those detected using conventional and confocal microscopy, Ca2+ waves observed with TIRFM exhibited fine inhomogenous substructures composed of fluctuating Ca2+ sparks. The anfractuous routes of spark recruitment suggested that the propagation of Ca2+ waves is much more complicated than previously imagined. We believe that TIRFM will provide a unique tool for dissecting the microscopic mechanisms of intracellular Ca2+ signaling.

  18. Near-wall nanovelocimetry based on Total Internal Reflection Fluorescence with continuous tracking

    CERN Document Server

    Li, Zhenzhen; Lee, Choongyeop; Monti, Fabrice; Yonger, Marc; Chollet, Benjamin; Bresson, Bruno; Tran, Yvette; Tabeling, Patrick

    2014-01-01

    The goal of this work is to make progress in the domain of near-wall velocimetry. The technique we use is based on the tracking of nanoparticles in an evanescent field, close to a wall, a technique called TIRF (Total Internal Reflection Fluorescence)-based velocimetry. At variance with the methods developed in the literature, we permanently keep track of the light emitted by each particle during the time the measurements of their positions ('altitudes') and speeds are performed. By performing the Langevin simulation, we quantified effect of biases such as Brownian motion, heterogeneities induced by the walls, statistical biases, photo bleaching, polydispersivity and limited depth of field. Using this method, we obtained slip length on hydrophilic surfaces of 1$ \\pm $5 nm for sucrose solution, and 9$ \\pm $10 nm for water; On hydrophobic surface, 32$ \\pm $5 nm for sucrose solution, and 55$ \\pm $9 nm for water. The errors (based on 95% confidence intervals) are significantly smaller than the state-of-the-art, bu...

  19. Preparation of Reactions for Imaging with Total Internal Reflection Fluorescence Microscopy.

    Science.gov (United States)

    Kudalkar, Emily M; Davis, Trisha N; Asbury, Charles L

    2016-01-01

    Here we present our standard protocol for studying the binding of kinetochore proteins to microtubules as a paradigm for designing single-molecule total internal reflection fluorescence (TIRF) microscopy experiments. Several aspects of this protocol require empirical optimization, including the method for anchoring the polymer or substrate to the coverslip, the type and amount of blocking protein to prevent nonspecific protein adsorption to the glass, the appropriate protein concentration, the laser power, and the duration of imaging. Our method uses bovine serum albumin and κ-casein as blocking agents to coat any imperfections in the coverslip silanization and thereby prevent protein adsorption to the coverslip. Protein concentration and duration of imaging must be optimized for each experiment and protein of interest. Ideally, a range is determined that allows for resolution of single complexes binding to microtubules to ensure proper measurement of kinetic off rates and diffusion along microtubules. Excessively high concentrations may lead to overlapping binding of proteins on microtubules, making it impossible to resolve single binding events. The duration of imaging must be long enough to capture very low off rates (long residence time on microtubules) and we typically image at 10 frames/sec for 200 sec. The laser power can be adjusted to prevent photobleaching, but must be high enough to achieve a sufficient signal/noise ratio. PMID:27140912

  20. Optical design and laser ablation of surface textures: demonstrating total internal reflection

    Science.gov (United States)

    Gommans, Hans; Booij, Silvia; Pijlman, Fetze; Krijn, Marcel; de Zwart, Siebe; Sepkhanov, Ruslan; Beaumont, Dave; van der Schaft, Hans; Sanders, Rene

    2015-09-01

    In lighting applications key drivers for optical design of surface textures are integration of optical elements, the disentanglement of optical functionality and appearance and late stage configuration. We investigated excimer laser ablation as a mastering technology for micro textured surfaces, where we targeted an increase in correspondence between surface design and ablated surface for high aspect ratio structures. To achieve this we have improved the photo mask design using a heuristic algorithm that corrects for the angular dependence of the ablation process and the loss of image resolution at ablation depths that exceed the depth of field. Using this approach we have been able to demonstrate close correspondence between designed and ablated facet structures up to 75° inclination at 75 μm depth. These facet design parameters allow for total internal reflection (TIR) as a means of beam deflection which is demonstrated in a range of mono shaped cone arrays in hexagonal tessellation. BSDF analysis was used to characterize the narrow TIR deflection beams that matched the peak positions of the design down to 28° apex. In addition, a single surface TIR-Fresnel lens design with focal distance 5 mm has been manufactured using this photo mask design algorithm and beam collimation up to 12° beam angle and 32° field angle is shown. These outcomes demonstrate that the laser ablation process intrinsically yields sufficient small dispersion in structure and fillet radii for lighting applications.

  1. Use of liposomal amplifiers in total internal reflection fluorescence fiber-optic biosensors for protein detection.

    Science.gov (United States)

    Chang, Ying-Feng; Fu, Chen; Chen, Yi-Ting; Fang-Ju Jou, Amily; Chen, Chii-Chang; Chou, Chien; Annie Ho, Ja-An

    2016-03-15

    Evanescent-wave excited fluorescence technology has been demonstrated to enhance sensitivity and reduce matrix effects, making it suitable for biosensor development. In this study, we developed a liposome-based, total internal reflection fluorescence, fiber-optic biosensor (TIRF-FOB) for protein detection, which integrates a liposomal amplifier and sandwich immunoassay format with TIRF-FOB. In addition, the antibody-tagged and fluorophore-entrapped liposomes for heterogeneous detection of target molecules were designed and synthesized. This biosensor successfully detected the target protein (model analyzed here is IgG) with a limit of detection (LOD) of 2.0 attomoles for the target protein (equivalent to 2.0 pg/mL of protein presented in 150 μL of sample solution). The features of this ultra-sensitive liposomal TIRF-FOB are (i) fluorescence is excited via evanescent waves and amplified via liposomes; (ii) the use of two polyclonal antibodies in the sandwich assay format increases the specificity and lowers the cost of our assay. Based on the exceptional detection sensitivity and cost-effectiveness, we believe that the proposed biosensor has great potential as a practical, clinical diagnostic tool in the near future. PMID:26595485

  2. Deconstructing the late phase of vimentin assembly by total internal reflection fluorescence microscopy (TIRFM.

    Directory of Open Access Journals (Sweden)

    Stefan Winheim

    Full Text Available Quantitative imaging of intermediate filaments (IF during the advanced phase of the assembly process is technically difficult, since the structures are several µm long and therefore they exceed the field of view of many electron (EM or atomic force microscopy (AFM techniques. Thereby quantitative studies become extremely laborious and time-consuming. To overcome these difficulties, we prepared fluorescently labeled vimentin for visualization by total internal reflection fluorescence microscopy (TIRFM. In order to investigate if the labeling influences the assembly properties of the protein, we first determined the association state of unlabeled vimentin mixed with increasing amounts of labeled vimentin under low ionic conditions by analytical ultracentrifugation. We found that bona fide tetrameric complexes were formed even when half of the vimentin was labeled. Moreover, we demonstrate by quantitative atomic force microscopy and electron microscopy that the morphology and the assembly properties of filaments were not affected when the fraction of labeled vimentin was below 10%. Using fast frame rates we observed the rapid deposition of fluorescently labeled IFs on glass supports by TIRFM in real time. By tracing their contours, we have calculated the persistence length of long immobilized vimentin IFs to 1 µm, a value that is identical to those determined for shorter unlabeled vimentin. These results indicate that the structural properties of the filaments were not affected significantly by the dye. Furthermore, in order to analyze the late elongation phase, we mixed long filaments containing either Alexa 488- or Alexa 647-labeled vimentin. The 'patchy' structure of the filaments obtained unambiguously showed the elongation of long IFs through direct end-to-end annealing of individual filaments.

  3. “Remotion” Total Wrist Arthroplasty: Preliminary Results of a Prospective International Multicenter Study of 215 Cases

    DEFF Research Database (Denmark)

    Herzberg, Guillaume; Boeckstyns, Michel Ernest Henri; Sorensen, Allan Ibsen;

    2012-01-01

    This study reports the current results of an international multicenter study of one last generation total wrist arthroplasty (TWA) ("ReMotion," Small Bone Innovation, Morristown, PA). The two first authors (G.H. and M.B.) built a Web-based prospective database including clinical and radiological ...

  4. A plastic total internal reflection-based photoluminescence device for enzymatic biosensors

    Science.gov (United States)

    Thakkar, Ishan G.

    Growing concerns for quality of water, food and beverages in developing and developed countries drive sizeable markets for mass-producible, low cost devices that can measure the concentration of contaminant chemicals in water, food, and beverages rapidly and accurately. Several fiber-optic enzymatic biosensors have been reported for these applications, but they exhibit very strong presence of scattered excitation light in the signal for sensing, requiring expensive thin-film filters, and their non-planar structure makes them challenging to mass-produce. Several other planar optical waveguide-based biosensors prove to be relatively costly and more fragile due to constituent materials and the techniques involved in their fabrication. So, a plastic total internal reflection (TIR)-based low cost, low scatter, field-portable device for enzymatic biosensors is fabricated and demonstrated. The design concept of the TIR-based photoluminescent enzymatic biosensor device is explained. An analysis of economical materials with appropriate optical and chemical properties is presented. PMMA and PDMS are found to be appropriate due to their high chemical resistance, low cost, high optical transmittance and low auto-fluorescence. The techniques and procedures used for device fabrication are discussed. The device incorporated a PMMA-based optical waveguide core and PDMS-based fluid cell with simple multi-mode fiber-optics using cost-effective fabrication techniques like molding and surface modification. Several techniques of robustly depositing photoluminescent dyes on PMMA core surface are discussed. A pH-sensitive fluorescent dye, fluoresceinamine, and an O2-sensitive phosphorescent dye, Ru(dpp) both are successfully deposited using Si-adhesive gel-based as well as HydroThane-based deposition methods. Two different types of pH-sensors using two different techniques of depositing fluoresceinamine are demonstrated. Also, the effect of concentration of fluoresceinamine-dye molecules

  5. Treatment of a slaughterhouse wastewater: effect of internal recycle rate on chemical oxygen demand, total Kjeldahl nitrogen and total phosphorus removal.

    Science.gov (United States)

    Fongsatitkul, P; Wareham, D G; Elefsiniotis, P; Charoensuk, P

    2011-12-01

    This study investigated the ability of an anaerobic/anoxic/oxic (A2/O) system to treat a slaughterhouse wastewater. The system employed two identical continuous-flow reactors (101 total liquid volume each) running in parallel with the main operational variable, being the internal recycle (IR) rate. The chemical oxygen demand (COD), total Kjeldahl nitrogen (TKN) and total phosphorus (TP) performance was evaluated as the IR flowrate was increased from a Q of 151d(-1) to 4Q at a system hydraulic retention time of 16 h and a solids retention time of 10 d. The COD:TKN and COD:TP ratios were 8.2:1 and 54:1, which supported both nitrogen and phosphorus removal. For all IR multiples of Q, the COD removal was in excess of 90%. The TKN removal showed a modest improvement (a 4-5% increase, depending on the dissolved oxygen (DO)) as the IR doubled from Q to 2Q, but no further increase was observed at the 4Q IR rate. The TP removal reached its optimum (around 85%-89% (again depending on the DO)) at the 2Q rate. PMID:22439562

  6. Blood volume, blood pressure and total body sodium: internal signalling and output control

    DEFF Research Database (Denmark)

    Bie, P

    2009-01-01

    . Plasma renin is log-linearly related to salt intake, and normally, decreases in renin secretion are a precondition of natriuresis after increases in total body sodium. Renin secretion is controlled by renal ABP, renal nerve activity and the tubular chloride concentrations at the macula densa (MD). Renal...

  7. 2002 results: TotalFinaElf makes a ''much better performance'' than the overall international oil groups

    International Nuclear Information System (INIS)

    T. Desmarest, head of TotalFinaElf oil and gas company, has presented the 2002 results of his company in the particular context of a moving international oil situation (the Iraq crisis and the situation in Venezuela) with important consequences on markets. At the same time, the company decided to change its name into 'Total' and to adopt a new logo. The results show a 17% drop with respect to 2001 but a 10% increase of the production. The high rate of exploration successes has led to the discovery of about 1 billion of bpe with a 0.8 US$ cost per bpe, which represents the best performance of the 5 world oil majors. The rate of reserves renewal reached 151% (11.2 billions of bpe at the end of 2002). The downstream activities (refining/distribution and basic chemistry) encountered much more problems for various reasons: low economic growth, climate warmth, international instability etc.. (J.S.)

  8. Methods for the measurement of the refractive index of MeV photons using total internal and external reflection

    International Nuclear Information System (INIS)

    Recently it has been theoretically and experimentally shown that for 1-10 MeV and 1-2 MeV photons, respectively, the refractive index of Si is greater than 1. Taking into account the difficulties of the carried out experiment it is proposed to measure directly the refractive index of Si and other materials detecting the total internal and external reflections.

  9. Status and trends in the development of Total Productive Maintenance (TPM) - a review of international articles

    DEFF Research Database (Denmark)

    Andreassen, Mads; Gertsen, Frank; Christiansen, Thomas Bøhm;

    2004-01-01

    maintenance and high efficiency of the production facilities. However, during the last ten years, the concepthas been developed into a company wide (management)concept, also compromising efficiency in the administrative part of a company, safety and environmental aspects, as well as product quality. Based on......Corporate continuous innovation efforts are often guided by (more or less) customized standard management concepts such as "TQM", "BPR" or "Lean". The focus of this article, Total Productive Maintenance (TPM), is a contemporary example of such a concept. Although the concept first appeared more...

  10. Status and trends in the development of Total Productive Maintenance (TPM) - a review of international articles

    DEFF Research Database (Denmark)

    Andreassen, Mads; Gertsen, Frank; Christiansen, Thomas Bøhm;

    2004-01-01

    Corporate continuous innovation efforts are often guided by (more or less) customized standard management concepts such as "TQM", "BPR" or "Lean". The focus of this article, Total Productive Maintenance (TPM), is a contemporary example of such a concept. Although the concept first appeared more...... maintenance and high efficiency of the production facilities. However, during the last ten years, the concepthas been developed into a company wide (management)concept, also compromising efficiency in the administrative part of a company, safety and environmental aspects, as well as product quality. Based on...

  11. Influence of Valve's Characteristic on Total Performance of Three Cylinders Internal Combustion Water Pump

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hongxin; ZHANG Tiezhu; WANG Weichao

    2009-01-01

    lntenal combustion pump (ICP) is a new type power device turning the thermal energy from fuel combustion into fluid pressure energy. Three cylinders prototype has just been developed. The study on the influence of valve's characteristic on ICP's total performance will found the base for its optimum design. Based on the theoretical and testing fruits of single cylinder prototype, the performance of the valves and complete appliance of the latest is simulated. When the natural frequency of valves is approximately to the round number times of the working frequency, volumetric efficiency is seriously low. The nominal rotational speed of the prototype is nearly to the speed where the volumetric efficiency is lowest, which is harmful to the normal work of ICP, so further structure optimization of valves should be carried out. The change of volumetric efficiency has great influence on the fuel consumption rate,output flow, effective thermal efficiency, effective power, and so on, but little on output pressure.

  12. Total internal reflection fluorescence (TIRF) microscopy for real-time imaging of nanoparticle-cell plasma membrane interaction

    DEFF Research Database (Denmark)

    Parhamifar, Ladan; Moghimi, Seyed Moien

    2012-01-01

    Nanoparticulate systems are widely used for site-specific drug and gene delivery as well as for medical imaging. The mode of nanoparticle-cell interaction may have a significant effect on the pathway of nanoparticle internalization and subsequent intracellular trafficking. Total internal reflecti...... effect by lasers in TIRF microscopy is considerably less when using fluorescent nanoparticles and it reduces photo-induced cytotoxicity during visualization of live-cell events since it only illuminates the specific area near or at the plasma membrane....... fluorescence (TIRF) microscopy allows for real-time monitoring of nanoparticle-membrane interaction events, which can provide vital information in relation to design and surface engineering of therapeutic nanoparticles for cell-specific targeting. In contrast to other microscopy techniques, the bleaching...

  13. High accuracy subwavelength distance measurements: A variable-angle standing-wave total-internal-reflection optical microscope

    International Nuclear Information System (INIS)

    We describe an extension of the total-internal-reflection microscopy technique that permits direct in-plane distance measurements with high accuracy (<10 nm) over a wide range of separations. This high position accuracy arises from the creation of a standing evanescent wave and the ability to sweep the nodal positions (intensity minima of the standing wave) in a controlled manner via both the incident angle and the relative phase of the incoming laser beams. Some control over the vertical resolution is available through the ability to scan the incoming angle and with it the evanescent penetration depth.

  14. Second Generation International Space Station (ISS) Total Organic Carbon Analyzer (TOCA) Verification Testing and On-Orbit Performance Results

    Science.gov (United States)

    Bentley, Nicole L.; Thomas, Evan A.; VanWie, Michael; Morrison, Chad; Stinson, Richard G.

    2010-01-01

    The Total Organic Carbon Analyzer (TOGA) is designed to autonomously determine recovered water quality as a function of TOC. The current TOGA has been on the International Space Station since November 2008. Functional checkout and operations revealed complex operating considerations. Specifically, failure of the hydrogen catalyst resulted in the development of an innovative oxidation analysis method. This method reduces the activation time and limits the hydrogen produced during analysis, while retaining the ability to indicate TOC concentrations within 25% accuracy. Subsequent testing and comparison to archived samples returned from the Station and tested on the ground yield high confidence in this method, and in the quality of the recovered water.

  15. Multiplex detection of histone-modifying enzymes by total internal reflection fluorescence-based single-molecule detection.

    Science.gov (United States)

    Ma, Fei; Liu, Meng; Wang, Zi-yue; Zhang, Chun-yang

    2016-01-21

    We develop a sensitive and selective method for the multiplex detection of histone-modifying enzymes (HMEs) through the integration of antibody-based fluorescence labeling with total internal reflection fluorescence (TIRF)-based single-molecule detection. This method exhibits excellent specificity and high sensitivity with a detection limit of 21 pM for histone acetyltransferase GcN5 and 12 pM for histone methyltransferase G9a, and it can be applied for the screening of HME inhibitors as well. PMID:26608941

  16. Is the Internal Rotation Lag Sign a Sensitive Test for Detecting Hip Abductor Tendon Ruptures after Total Hip Arthroplasty?

    Directory of Open Access Journals (Sweden)

    Simmen Hans-Peter

    2011-04-01

    Full Text Available Abstract Introduction Total hip arthroplasty (THA is one of the most frequently performed procedures in orthopaedics and weakness of external rotators is often recognized thereafter. However, the etiology of lateral hip pain is multifaceted. For the diagnosis of abductor tendon rupture, magnetic resonance imaging (MRI is the gold standard. As not every patient can be subjected to MRI, a clinical diagnostic test for easy detection of lesions of the abductor tendon is missing. Here, we present the internal rotation lack sign indicating abductor tendon pathology. Methods The patient is placed in lateral position on a stretcher with hips and knees in neutral position. The knee is flexed to 45° and the hip passively abducted and elevated by the investigator. With the foot passively abducted, the patient is then asked to bring his knee in direction to the examination table. This motion is also tested passively. The test is regarded positive, if no internal rotation is possible and/or if this is painful. If groin pain is elicited during either of the exercises, the test is also rated positive. Results We evaluated this test in 20 patients clinically and by magnetic resonance imaging (MRI. All patients demonstrated a positive internal rotation lag sign. Twelve of them lag of internal rotation and evidence of anterior abductor tendon rupture on MRI, 8 with lag of internal rotation and no evidence of abductor tendon rupture. Conclusion The new clinical diagnostic sign presented here may improve the diagnosis of abductor tendon rupture in the future. Level of Evidence: Diagnostic study, level I.

  17. Fluorescently-Labeled Estradiol Internalization and Membrane Trafficking in Live N-38 Neuronal Cells Visualized with Total Internal Reflection Fluorescence Microscopy.

    Science.gov (United States)

    Kisler, Kassandra; Chow, Robert H; Dominguez, Reymundo

    2013-04-20

    Estradiol is a steroid hormone that binds and activates estradiol receptors. Activation of these receptors is known to modulate neuronal physiology and provide neuroprotection, but it is not completely understood how estradiol mediates these actions on the nervous system. Activation of a sub-population of estradiol receptor-α (ERα), originally identified as a nuclear protein, localizes to the plasma membrane and appears to be a critical step in neuroprotection against brain injury and disease. Previously we showed that estradiol stimulates the rapid and transient trafficking of plasma membrane ERα in primary hypothalamic neurons, and internalization of membrane-impermeant estradiol (E6BSA-FITC) into cortical neuron endosomes in vitro. These findings support the concept that estradiol activates and down-regulates plasma membrane ERα by triggering endocytosis. Here, we use TIRFM (total internal reflection fluorescence microscopy) to image the trafficking of E6BSA-FITC, and GFP-labeled ERα, in live cells in real time. We show that activation of plasma membrane ERs by E6BSA-FITC result in internalization of the fluorescent ligand in live N-38 neurons, an immortalized hypothalamic cell line. Pretreatment with ER antagonist ICI 182,780 decreased the number of E6BSA-FITC labeled puncta observed. We also observed in live N-38 neurons that E6BSA-FITC co-localized with FM4-64 and LysoTracker fluorescent dyes that label endosomes and lysosomes. Our results provide further evidence that plasma membrane ERα activation results in endocytosis of the receptor. PMID:24353903

  18. In-situ analysis of fruit anthocyanins by means of total internal reflectance, continuous wave and time-resolved spectroscopy

    Science.gov (United States)

    Zude, Manuela; Spinelli, Lorenzo; Dosche, Carsten; Torricelli, Alessandro

    2009-08-01

    In sweet cherry (Prunus avium), the red pigmentation is correlated with the fruit maturity stage and can be measured by non-invasive spectroscopy. In the present study, the influence of varying fruit scattering coefficients on the fruit remittance spectrum (cw) were corrected with the effective pathlength and refractive index in the fruit tissue obtained with distribution of time-of-flight (DTOF) readings and total internal reflection fluorescence (TIRF) analysis, respectively. The approach was validated on fruits providing variation in the scattering coefficient outside the calibration sample set. In the validation, the measuring uncertainty when non-invasively analyzing fruits with cw method in comparison with combined application of cw, DTOF, and TIRF measurements showed an increase in r2 up to 22.7 % with, however, high errors in all approaches.

  19. A total internal reflection fluorescence microscopy study of mass diffusion enhancement in water-based alumina nanofluids

    Science.gov (United States)

    Veilleux, Jocelyn; Coulombe, Sylvain

    2010-11-01

    Mass diffusion of rhodamine 6G (R6G) in water-based alumina nanofluids is studied by means of total internal reflection fluorescence (TIRF) microscopy. We report a mass diffusivity enhancement that reaches an order of magnitude in a 2 vol % nanofluid when compared to the value in deionized water. Since experiments were performed with positively charged R6G, interfacial complexation between the dye and the nanoparticles was not observed. The effect of local density variations on mass diffusivity measurements is also addressed. An explanation for the enhancement of mass diffusion is presented using arguments based on dispersion, and it is shown that it correctly describes the order of magnitude differences between the thermal conductivity and mass diffusivity enhancements reported in the literature.

  20. International Review Team (IRT) Safety Case Recommendations for the Yucca Mountain Total System Performance Assessment (TSPA) Supporting the Site Recommendation

    International Nuclear Information System (INIS)

    The session started with Abe Van Luik (IGSC Chair, US-DOE-YM, USA) who presented the feedback of the international peer review of the US-DOE Yucca Mountain TSPA (Total System Performance Assessment) supporting the successful designation of the site by the Congress and the President of the U.S. In particular, he listed key implications of the IRT (International Review team) recommendations on the forthcoming US-DOE documentation of its case for safety to be submitted to the regulator, the U.S. Nuclear Regulatory Commission, mainly: - The documentation submitted to the licensing authority should address technical aspects and compliance with regulatory criteria. - That documentation should reflect sound science and good engineering practice; it should present detailed and rigorous modelling. - In addition, it should present both quantitative and qualitative arguments, make a statement on why there can be confidence in the face of uncertainty, acknowledge remaining issues and provide the strategy to resolve them. - Demonstrating understanding is as important as demonstrating compliance. - There is a need to provide a clear explanation of the case made to the regulator for more general audiences to complement the large amount of technical documents that will be produced. The US-DOE response to these recommendations for the License Application, which is under preparation, is that the recommendations will be implemented to the maximum extent possible. In subsequent discussion, with respect to the License Application, it was acknowledged that detailed guidance from the U.S. regulator was very useful, and guidance of this type would be generally useful. At the current time, the words 'safety case' are not mentioned in U.S. regulations, but if one reads both the regulation and guidance documents it becomes evident that all aspects of a safety case need to be provided in the License Application and its accompanying documents

  1. Pharmacokinetic detection of penicillin excreted in urine using a totally internally reflected resonance light scattering technique with cetyltrimethylammonium bromide.

    Science.gov (United States)

    Huang, Cheng Zhi; Feng, Ping; Li, Yuan Fang; Tan, Ke Jun

    2005-05-01

    A quantitative analysis method for penicillins including ampicillin (AmP), benzyl penicillin (BP), oxacillin (OA) and amoxycillin (AmO) is proposed that makes use of the totally internally reflected resonance light scattering (TIR-RLS) signal from the penicillin at the H2O/CCl4 interface in the presence of cetyltrimethylammonium bromide (CTMAB), and enables the pharmacokinetics of penicillin taken orally and excreted through urine to be monitored. Penicillin is coadsorbed with CTMAB at the H2O/CCl4 interface in neutral solution, resulting in the formation of ion associates that display greatly enhanced TIR-RLS signals (maximum at 368-372 nm). This enhanced TIR-RLS intensity was found to be proportional to the penicillin concentration over the range 0.2 x 10(-6) to 2.2 x 10(-6) mol L(-1), with limits of determination (3sigma) of 5.0 x 10(-8) to 7.0 x 10(-8) mol L(-1). Pharmacokinetics studies performed using the present method show that the excretion of orally-taken ampicillin through urine has a half-time of 1.05 h and an excremental quantum over 8 h of 49.3%, respectively. PMID:15900456

  2. Characterization of GLUT4-containing vesicles in 3T3-L1 adipocytes by total internal reflection fluorescence microscopy

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Insulin-responsive GLUT4(glucose transporter 4) translocation plays a major role in regulating glucose uptake in adipose tissue and muscle.Whether or not there is a specialized secretory GSV(GLUT4 storage vesicle) pool,and more importantly how GSVs are translocated to the PM(plasma membrane) under insulin stimulation is still under debate.In the present study,we systematically analyzed the dynamics of a large number of single GLUT4-containing vesicles in 3T3-L1 adipocytes by TIRFM(total internal reflection fluorescence microscopy).We found that GLUT4-containing vesicles can be classified into three groups according to their mobility,namely vertical,stable,and lateral GLUT4-containing vesicles.Among these groups,vertical GLUT4-containing vesicles exclude transferrin receptors and move towards the PM specifically in response to insulin stimulation,while stable and lateral GLUT4-containing vesicles contain transferrin receptors and show no insulin responsiveness.These data demonstrate that vertical GLUT4-containing vesicles correspond to specialized secretory GSVs,which approach the PM directly and bypass the constitutive recycling pathway.

  3. Planar solar concentrator featuring alignment-free total-internal-reflection collectors and an innovative compound tracker.

    Science.gov (United States)

    Teng, Tun-Chien; Lai, Wei-Che

    2014-12-15

    This study proposed a planar solar concentrator featuring alignment-free total-internal-reflection (TIR) collectors and an innovative compound tracker. The compound tracker, combining a mechanical single-axis tracker and scrollable prism sheets, can achieve a performance on a par with dual-axis tracking while reducing the cost of the tracking system and increasing its robustness. The alignment-free TIR collectors are assembled on the waveguide without requiring alignment, so the planar concentrator is relatively easily manufactured and markedly increases the feasibility for use in large concentrators. Further, the identical TIR collector is applicable to various-sized waveguide slab without requiring modification, which facilitates flexibility regarding the size of the waveguide slab. In the simulation model, the thickness of the slab was 2 mm, and its maximal length reached 6 m. With an average angular tolerance of ±0.6°, and after considering both the Fresnel loss and the angular spread of the sun, the simulation indicates that the waveguide concentrator of a 1000-mm length provides the optical efficiencies of 62-77% at the irradiance concentrations of 387-688, and the one of a 2000-mm length provides the optical efficiencies of 52-64.5% at the irradiance concentrations of 645-1148. Alternatively, if a 100-mm horizontally staggered waveguide slab is collocated with the alignment-free TIR collectors, the optical efficiency would be greatly improved up to 91.5% at an irradiance concentration of 1098 (C(geo) = 1200X). PMID:25607496

  4. Exact Space-Time Gauge Symmetry of Gravity, Its Couplings and Approximate Internal Symmetries in a Total-Unified Model

    CERN Document Server

    Hsu, Jong-Ping

    2013-01-01

    Gravitational field is the manifestation of space-time translational ($T_4$) gauge symmetry, which enables gravitational interaction to be unified with the strong and the electroweak interactions. Such a total-unified model is based on a generalized Yang-Mills framework in flat space-time. Following the idea of Glashow-Salam-Ward-Weinberg, we gauge the groups $T_4 \\times (SU_3)_{color} \\times SU_2 \\times U_1\\times U_{1b}$ on equal-footing, so that we have the total-unified gauge covariant derivative ${\\bf \\d}_{\\mu} = \\p_{\\mu} - ig\\phi_{\\mu}^{\

  5. Development and Improvement of Internal Audit in the Perspective of Total Quality Management%论内部审计的全面质量管理

    Institute of Scientific and Technical Information of China (English)

    周燕; 侯翠婷

    2012-01-01

    从全面质量管理理论基础入手,利用现代管理学相关的观点,结合内部审计的质量和质量管理,从高度关注顾客、坚持持续改进、重视全过程改进组织各项工作的质量、遵照执行明确的质量标准、全员参与质量管理这五个维度详细论述了内部审计全面质量管理的内容与方法,提出了人力资源、责任制度及作业技术水平是内部审计全面质量管理的三大保障要素。%From the theoretical basis of Total Quality Management, combined with the view ot moaern manage- ment, internal audit,. From the theory of total quality management foundation, using the modern management science point of view, combining with the internal audit quality and quality management, the article detailed dis- cussed the content and the method of Total Quality Management from the highly pay attention to the customer, adhering to continuous improvement, thinking highly of the entire process improvement of the organization's work quality, conforming to specific quality standard, full participation in quality management, and put forward the three security elements of manpower resource, responsibility system and operation technical level to carry out Total Quality Management of internal audit.

  6. The Achilles tendon total rupture score: a study of responsiveness, internal consistency and convergent validity on patients with acute Achilles tendon ruptures

    Directory of Open Access Journals (Sweden)

    Kearney Rebecca S

    2012-02-01

    Full Text Available Abstract Background The Achilles tendon Total Rupture Score was developed by a research group in 2007 in response to the need for a patient reported outcome measure for this patient population. Beyond this original development paper, no further validation studies have been published. Consequently the purpose of this study was to evaluate internal consistency, convergent validity and responsiveness of this newly developed patient reported outcome measure within patients who have sustained an isolated acute Achilles tendon rupture. Methods Sixty-four eligible patients with an acute rupture of their Achilles tendon completed the Achilles tendon Total Rupture Score alongside two further patient reported outcome measures (Disability Rating Index and EQ 5D. These were completed at baseline, six weeks, three months, six months and nine months post injury. The Achilles tendon Total Rupture Score was evaluated for internal consistency, using Cronbach's alpha, convergent validity, through correlation analysis and responsiveness, by analysing floor and ceiling effects and calculating its relative efficiency in comparison to the Disability Rating Index and EQ 5D scores. Results The Achilles tendon Total Rupture Score demonstrated high internal consistency (Cronbachs alpha > 0.8 and correlated significantly (p Conclusions A universally accepted outcome measure is imperative to allow comparisons to be made across practice. This is the first study to evaluate aspects of validity of this newly developed outcome measure, outside of the developing centre. The ATRS demonstrated high internal consistency and responsiveness, with limited convergent validity. This research provides further support for the use of this outcome measure, however further research is required to advocate its universal use in patients with acute Achilles tendon ruptures. Such areas include inter-rater reliability and research to determine the minimally clinically important difference

  7. News and Views: A total solar eclipse over Rapa Nui; ESA's vision; International team wins first Ambartsumian Prize; Thinner thermosphere; ESA funds games; Team finds starspots

    Science.gov (United States)

    2010-10-01

    Francisco Diego recorded spectacular images of the 11 July 2010 total solar eclipse from Rapa Nui (Easter Island), making the most of modern digital technology - much of which originated from astronomical research - in taking and processing the images. The European Space Agency has set out its priorities for the decade starting in 2015, in a report entitled Cosmic Vision. The first Viktor Ambartsumian International Prize, in memory of the distinguished Armenian theorist, goes to the team led by Prof. Michel Mayor of the Observatory of Geneva, for ``their important contribution in the study of relation between planetary systems and their host stars''.

  8. Novel Folding Large-Scale Optical Switch Matrix with Total Internal Reflection Mirrors on Silicon-on-Insulator by Anisotropy Chemical Etching

    Institute of Scientific and Technical Information of China (English)

    LIU Jing-Wei; YU Jin-Zhong; CHEN Shao-Wu

    2005-01-01

    A compact optical switch matrix was designed, in which light circuits were folded by total internal reflective (TIR) mirrors. Two key elements, 2 × 2 switch and TIR mirror, have been fabricated on silicon-on-insulator wafer by anisotropy chemical etching. The 2 × 2 switch showed very low power consumption of 140mW and avery high speed of 8 ± 1 μs. An improved design for the TIR mirror was developed, and the fabricated mirror with smooth and vertical reflective facet showed low excess loss of 0.7 ± 0.3 dB at 1.55μm.

  9. Use of total internal reflection Raman (TIR) and attenuated total reflection infrared (ATR-IR) spectroscopy to analyze component separation in thin offset ink films after setting on coated paper surfaces.

    Science.gov (United States)

    Kivioja, Antti; Hartus, Timo; Vuorinen, Tapani; Gane, Patrick; Jääskeläinen, Anna-Stiina

    2013-06-01

    The interactive behavior of ink constituents with porous substrates during and after the offset print process has an important effect on the quality of printed products. To help elucidate the distribution of ink components between the retained ink layer and the substrate, a variety of spectroscopic and microscopic analysis techniques have been developed. This paper describes for the first time the use of total internal reflection (TIR) Raman spectroscopy to analyze the penetration behavior of separated offset ink components (linseed oil, solid color pigment) in coated papers providing chemically intrinsic information rapidly, nondestructively, and with minimal sample preparation. In addition, the already widely applied technique of attenuated total reflection infrared spectroscopy (ATR-IR) was evaluated in parallel and compared. The results of the ATR-IR Raman clearly revealed an improvement in uppermost depth resolution compared with values previously published from other nondestructive techniques, and the method is shown to be capable of providing new knowledge of the setting of thin (0.25-2 μm) offset ink films, allowing the spreading and the penetration behavior on physically different paper coating surfaces to be studied. PMID:23735252

  10. Optical interrupter based in the internal total reflection of spatial solitons at nonlinear saturable interfaces; Interruptores opticos basados en reflexion interna total de solitones espaciales en interfaces no lineales saturables

    Energy Technology Data Exchange (ETDEWEB)

    Alvarado-Mendez, E.; Torres-Cisneros, M.; Gutierrez-Hernandez, D. A.; Andrade-Lucio, J. A.; Rojas-Lagunas, R.; Pedraza-Ortega, J. C.; Torres Cisneros, G. E. [Universidad de Guanajuato, Guanajuato (Mexico); Sanchez Mondragon, J. J. [Universidad Autonoma del Estado de Morelos, Morelos (Mexico); Flores-Alvarado, G. [Preparatoria por Cooperacion Domingo Arenas, Tlaxcala (Mexico)

    2001-06-01

    We study the reflection of one-dimensional spatial soliton at the nonlinear interface between a saturable type medium and linear medium. Our study makes emphasis on determining the physical conditions under which the beam reflected by the interface is still a spatial soliton. Depended the incidence angle we find three critical regions for spatial solitons in the interface. We observed nonlinear Goos- Haechen shift is determined if reflection angle are conserved. Finally, we present preliminary experimental results in SBN61:Ce of the total internal reflection of one dimensional beam. [Spanish] Estudiamos la reflexion de un soliton espacial unidimensional en una interfase formada por un medio no lineal saturable y un medio lineal. Nuestros estudios hacen enfasis en determinar las condiciones fisicas bajo las cuales el haz reflejado por la interfase no lineal sigue siendo soliton. Encontramos tres regiones criticas para un soliton especial en la interfase, dependiendo del valor que tome el angulo de incidencia. Asi mismo observamos corrimiento Goos-Haechen no lineal que es determinante para la conservacion del angulo de reflexion. Finalmente, presentamos resultados preliminares experimentales en SBN61:Ce de la reflexion interna total de un haz unidimensional.

  11. International

    International Nuclear Information System (INIS)

    This rubric reports on 10 short notes about international economical facts about nuclear power: Electricite de France (EdF) and its assistance and management contracts with Eastern Europe countries (Poland, Hungary, Bulgaria); Transnuclear Inc. company (a 100% Cogema daughter company) acquired the US Vectra Technologies company; the construction of the Khumo nuclear power plant in Northern Korea plays in favour of the reconciliation between Northern and Southern Korea; the delivery of two VVER 1000 Russian reactors to China; the enforcement of the cooperation agreement between Euratom and Argentina; Japan requested for the financing of a Russian fast breeder reactor; Russia has planned to sell a floating barge-type nuclear power plant to Indonesia; the control of the Swedish reactor vessels of Sydkraft AB company committed to Tractebel (Belgium); the renewal of the nuclear cooperation agreement between Swiss and USA; the call for bids from the Turkish TEAS electric power company for the building of the Akkuyu nuclear power plant answered by three candidates: Atomic Energy of Canada Limited (AECL), Westinghouse (US) and the French-German NPI company. (J.S.)

  12. Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy

    International Nuclear Information System (INIS)

    To analyze the exocytosis of glucagon-like peptide-1 (GLP-1) granules, we imaged the motion of GLP-1 granules labeled with enhanced yellow fluorescent protein (Venus) fused to human growth hormone (hGH-Venus) in an enteroendocrine cell line, STC-1 cells, by total internal reflection fluorescent (TIRF) microscopy. We found glucose stimulation caused biphasic GLP-1 granule exocytosis: during the first phase, fusion events occurred from two types of granules (previously docked granules and newcomers), and thereafter continuous fusion was observed mostly from newcomers during the second phase. Closely similar to the insulin granule fusion from pancreatic β cells, the regulated biphasic exocytosis from two types of granules may be a common mechanism in glucose-evoked hormone release from endocrine cells.

  13. Three-dimensional particle tracking around microstructures in water via total internal reflection fluorescence microscopy and refractive-index-matching method

    Science.gov (United States)

    Unno, Noriyuki; Nakata, Shuichiro; Satake, Shin-ichi; Taniguchi, Jun

    2016-07-01

    Multilayer nanoparticle image velocimetry (MnPIV) with a refractive-index-matching method is powerful technique for x- y- z (3D) flow measurement, because it can detect the 3D position of fluorescent particles with submicron resolution. In MnPIV, the intensity of fluorescence of a particle is used to estimate its z-position. However, it has been difficult to measure 3D flows around microstructures in water by total internal reflection fluorescence microscopy because of light scattering caused by the different refractive indices of the structures and the working fluid. By using a thermal nanoimprinting technique, we succeeded in fabricating microstructures from a polymer resin whose refractive index is equal to that of water, and we used these microstructures to perform MnPIV in water. As a result of the match between the refractive index of water and that of the microstructures, we were able to perform 3D tracking of nanoparticles around the microstructures in water.

  14. Fermat's Principle in Curved Space-time, No Emission from Schwarzschild Black Holes as Total Internal Reflection and Black Hole Unruh effect

    CERN Document Server

    Mitra, Soma

    2015-01-01

    Using the Fermat's principle in curved space-time with stationary type metric, we have obtained the speed of light as a function of spatial coordinates and hence the corresponding refractive index. The whole region with space dependent gravity is divided into a number of overlapping transparent refracting media with varying refractive index. The refractive index is found to be increasing with the strength of gravitational field. Hence using the laws of refraction, we have explained the gravitational bending of light. Further using the conventional idea of total internal reflection of light while going from denser to rarer medium, in the present scenario it is the propagation of light from the region of ultra-strong gravitational field to relatively weaker gravitational field region, we have proposed an alternative approach for no emission of any kind of electromagnetic radiation from the surface of a classical Schwarzschild Black Hole. We have further noticed that for an observer in a uniformly accelerated fr...

  15. Total internal reflection without change of polarization using a right-angle prism with half-wavelength-thick optical interference coating.

    Science.gov (United States)

    Azzam, R M A

    2009-02-01

    Monochromatic light, which is polarized in an arbitrary state, is totally internally reflected at angle of incidence phi=45 degrees without change of polarization by a right-angle prism of refractive index n0=1+1/Square root of 2=1.70711 (e.g., N-LAK8 Schott glass at wavelength lambda=706 nm), which is coated with a transparent thin film of refractive index n1=(1+1/2)1/2=1.30656 (e.g., vacuum-deposited fluoride material) and of metric thickness equal to half of the vacuum wavelength of incident light, d=lambda/2. The ambient medium of evanescent refraction is assumed to be vacuum, air, or an inert gas. Wavelength shifts of +/-50 nm, or changes of the internal angle of incidence of +/-1 degrees around 45 degrees, cause phase errors of only a few degrees. The reflected and incident polarization states are nearly identical in the presence of such small phase errors. PMID:19183662

  16. Determination of Proteins by Measuring Total Internal-reflected Resonance Light Scattering Signals on Water/Tetrachloromethane Interface with Evans Blue and Cetyltrimethylammonium Bromide

    Institute of Scientific and Technical Information of China (English)

    HUANG Cheng-zhi; FENG Ping; LI Yuan-fang; ZHAO Hua-wen

    2005-01-01

    A sensitive and selective assay of proteins is proposed based on measuring the total internal-reflected resonance light scattering(TIR-RLS) signals produced on the water/tetrachloromethane(H2O/CCl4) interface. In an aqueous medium with pH value in the range of 3.29-3.78, electrostatic attraction occurs between the negatively charged Evans Blue(EB) and positively charged proteins, forming hydrophobic ion associates and resulting in EB-protein adsorption on H2O/CCl4 interface. The presence of cetyltrimethylammonium bromide prompts this adsorption, resulting in strongly enhanced TIR-RLS signals. The intensity of the enhanced TIR-RLS at 360-370 nm was found to be proportional to the concentration of proteins. For bovine serum albumin and human serum albumin, the linear range of detection is 0.07-1.2 μg/mL and the limits of detection are 6.68 and 6.30 ng/mL(3σ), respectively, while for lysozyme, the linear range of detection is 0.06-1.0 μg/mL and the limit of detection is 6.0 ng/mL(3σ). The content of the total albumin in a human urine sample could be directly determined by using the standard addition method with a percent recovery of 97.6%-104.1%, and the RSD ranging from 1.9% to 4.2%.

  17. Total internal reflection plasmonic scattering-based fluorescence-free nanoimmunosensor probe for ultra-sensitive detection of cancer antigen 125.

    Science.gov (United States)

    Chakkarapani, Suresh Kumar; Zhang, Peng; Ahn, Sujin; Kang, Seong Ho

    2016-07-15

    Highly sensitive detection of cancer antigen 125 (CA125) on nanoarray chips was carried out by means of total internal reflection (TIR) microscopy based on fluorescent labeling (i.e., TIR fluorescence microscopy; TIRFM) and fluorescent-free labeling (TIR scattering microscopy; TIRSM). TIR plasmonic scattering of nanoparticles (NPs) as a fluorescence-free immunosensor probe potentially superior to fluorescent probes was applied to quantify CA125 on a nanoarray chip. NP-labeled CA125 (NP-CA125) was immunoreacted on chips, and the TIR scattering illumination of NP-CA125 allowed quantitative TIRSM measurement of wavelength-dependent plasmonic scattering detection of CA125. In addition, Alexafluor 488-labeled CA125 was immunoreacted on the same chips for comparison of detection sensitivity. TIRSM showed less photobleaching and higher photostability and detection sensitivity than TIRFM, as well as a lower limit of detection (LOD), 0.0018U/mL. This LOD was ~144 times lower than that of previously reported detection methods. These results demonstrated that the wavelength-dependent TIR plasmon NPs can be used as an enhanced nanoimmunosensor probe, providing ultra-sensitive fluorescence-free biomolecule detection to enable earliest-stage disease diagnosis. PMID:26913504

  18. Single molecule investigations of DNA looping using the tethered particle method and translocation by acto-myosin using polarized total internal reflection fluorescence microscopy

    Science.gov (United States)

    Beausang, John F.

    Single molecule biophysics aims to understand biological processes by studying them at the single molecule level in real time. The proteins and nucleic acids under investigation typically exist in an aqueous environment within ˜ ten degrees of room temperature. These seemingly benign conditions are actually quite chaotic at the nanoscale, where single bio-molecules perform their function. As a result, sensitive experiments and statistical analyses are required to separate the weak single molecule signal from its background. Protein-DNA interactions were investigated by monitoring DNA looping events in tethered particle experiments. A new analysis technique, called the Diffusive hidden Markov method, was developed to extract kinetic rate constants from experimental data without any filtering of the raw data; a common step that improves the signal to noise ratio, but at the expense of lower time resolution. In the second system, translocation of the molecular motor myosin along its actin filament track was studied using polarized total internal reflection (polTIRF) microscopy, a technique that determines the orientation and wobble of a single fluorophore attached to the bio-molecule of interest. The range of resolvable angles was increased 4-fold to include a hemisphere of possible orientations. As a result, the handedness of actin filament twirling as it translocated along a myosin-coated surface was determined to be left-handed. The maximum time resolution of a polTIRF setup was increased 50-fold, in part by recording the arrival times and polarization state of single photons using a modified time-correlated single photon counting device. A new analysis, the Multiple Intensity Change Point algorithm, was developed to detect changes in molecular orientation and wobble using the raw time-stamped data with no user-defined bins or thresholds. The analysis objectively identified changes in the orientation of a bifunctional-rhodamine labeled calmodulin that was attached

  19. Total protein

    Science.gov (United States)

    The total protein test measures the total amount of two classes of proteins found in the fluid portion of your ... nutritional problems, kidney disease or liver disease . If total protein is abnormal, you will need to have more ...

  20. Total protein

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003483.htm Total protein To use the sharing features on this page, please enable JavaScript. The total protein test measures the total amount of two classes ...

  1. Total ‘rib’-preservation technique of internal mammary vessel exposure for free flap breast reconstruction: A 5-year prospective cohort study and instructional video

    Directory of Open Access Journals (Sweden)

    Anais Rosich-Medina

    2015-09-01

    Discussion & conclusion: The total ‘rib’-preservation technique of IMV exposure is a safe, reliable and versatile method for microvascular breast reconstruction and should be considered as a valid alternative to the ‘rib’-sacrificing techniques.

  2. Multi-institutional Feasibility Study of a Fast Patient Localization Method in Total Marrow Irradiation With Helical Tomotherapy: A Global Health Initiative by the International Consortium of Total Marrow Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Yutaka [Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota (United States); Vagge, Stefano; Agostinelli, Stefano [Department of Radiation Oncology, Instituto Nazionale per la Ricerca sul Cancro–National Institute for Cancer Research and University of Genoa, Genoa (Italy); Han, Eunyoung [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Matulewicz, Lukasz [Department of Radiation Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice (Poland); Schubert, Kai [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Chityala, Ravishankar [Department of Therapeutic Radiology, University of Minnesota, Minneapolis, Minnesota (United States); Minnesota Super Computer Institute, University of Minnesota, Minneapolis, Minnesota (United States); Ratanatharathorn, Vaneerat [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Tournel, Koen [Department of Radiotherapy, Universitair Ziekenhuis Brussel, Brussels (Belgium); Penagaricano, Jose A. [Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Florian, Sterzing [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Mahe, Marc-Andre [Department of Radiation Oncology, Integrated Center of Oncology–René Gauducheau, Saint-Herblain Cédex (France); Verneris, Michael R. [Divisions of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota (United States); Weisdorf, Daniel J. [Department of Medicine, University of Minnesota, Minneapolis, Minnesota (United States); and others

    2015-01-01

    Purpose: To develop, characterize, and implement a fast patient localization method for total marrow irradiation. Methods and Materials: Topographic images were acquired using megavoltage computed tomography (MVCT) detector data by delivering static orthogonal beams while the couch traversed through the gantry. Geometric and detector response corrections were performed to generate a megavoltage topogram (MVtopo). We also generated kilovoltage topograms (kVtopo) from the projection data of 3-dimensional CT images to reproduce the same geometry as helical tomotherapy. The MVtopo imaging dose and the optimal image acquisition parameters were investigated. A multi-institutional phantom study was performed to verify the image registration uncertainty. Forty-five MVtopo images were acquired and analyzed with in-house image registration software. Results: The smallest jaw size (front and backup jaws of 0) provided the best image contrast and longitudinal resolution. Couch velocity did not affect the image quality or geometric accuracy. The MVtopo dose was less than the MVCT dose. The image registration uncertainty from the multi-institutional study was within 2.8 mm. In patient localization, the differences in calculated couch shift between the registration with MVtopo-kVtopo and MVCT-kVCT images in lateral, cranial–caudal, and vertical directions were 2.2 ± 1.7 mm, 2.6 ± 1.4 mm, and 2.7 ± 1.1 mm, respectively. The imaging time in MVtopo acquisition at the couch speed of 3 cm/s was <1 minute, compared with ≥15 minutes in MVCT for all patients. Conclusion: Whole-body MVtopo imaging could be an effective alternative to time-consuming MVCT for total marrow irradiation patient localization.

  3. Multi-institutional Feasibility Study of a Fast Patient Localization Method in Total Marrow Irradiation With Helical Tomotherapy: A Global Health Initiative by the International Consortium of Total Marrow Irradiation

    International Nuclear Information System (INIS)

    Purpose: To develop, characterize, and implement a fast patient localization method for total marrow irradiation. Methods and Materials: Topographic images were acquired using megavoltage computed tomography (MVCT) detector data by delivering static orthogonal beams while the couch traversed through the gantry. Geometric and detector response corrections were performed to generate a megavoltage topogram (MVtopo). We also generated kilovoltage topograms (kVtopo) from the projection data of 3-dimensional CT images to reproduce the same geometry as helical tomotherapy. The MVtopo imaging dose and the optimal image acquisition parameters were investigated. A multi-institutional phantom study was performed to verify the image registration uncertainty. Forty-five MVtopo images were acquired and analyzed with in-house image registration software. Results: The smallest jaw size (front and backup jaws of 0) provided the best image contrast and longitudinal resolution. Couch velocity did not affect the image quality or geometric accuracy. The MVtopo dose was less than the MVCT dose. The image registration uncertainty from the multi-institutional study was within 2.8 mm. In patient localization, the differences in calculated couch shift between the registration with MVtopo-kVtopo and MVCT-kVCT images in lateral, cranial–caudal, and vertical directions were 2.2 ± 1.7 mm, 2.6 ± 1.4 mm, and 2.7 ± 1.1 mm, respectively. The imaging time in MVtopo acquisition at the couch speed of 3 cm/s was <1 minute, compared with ≥15 minutes in MVCT for all patients. Conclusion: Whole-body MVtopo imaging could be an effective alternative to time-consuming MVCT for total marrow irradiation patient localization

  4. Total algorithms

    NARCIS (Netherlands)

    Tel, G.

    1993-01-01

    We define the notion of total algorithms for networks of processes. A total algorithm enforces that a "decision" is taken by a subset of the processes, and that participation of all processes is required to reach this decision. Total algorithms are an important building block in the design of distri

  5. Microarchitecture and Peripheral BMD are Impaired in Postmenopausal White Women With Fracture Independently of Total Hip T-Score: An International Multicenter Study.

    Science.gov (United States)

    Boutroy, Stephanie; Khosla, Sundeep; Sornay-Rendu, Elisabeth; Zanchetta, Maria Belen; McMahon, Donald J; Zhang, Chiyuan A; Chapurlat, Roland D; Zanchetta, Jose; Stein, Emily M; Bogado, Cesar; Majumdar, Sharmila; Burghardt, Andrew J; Shane, Elizabeth

    2016-06-01

    Because single-center studies have reported conflicting associations between microarchitecture and fracture prevalence, we included high-resolution peripheral quantitative computed tomography (HR-pQCT) data from five centers worldwide into a large multicenter analysis of postmenopausal women with and without fracture. Volumetric BMD (vBMD) and microarchitecture were assessed at the distal radius and tibia in 1379 white postmenopausal women (age 67 ± 8 years); 470 (34%) had at least one fracture including 349 with a major fragility fracture. Age, height, weight, and total hip T-score differed across centers and were employed as covariates in analyses. Women with fracture had higher BMI, were older, and had lower total hip T-score, but lumbar spine T-score was similar between groups. At the radius, total and trabecular vBMD and cortical thickness were significantly lower in fractured women in three out of five centers, and trabecular number in two centers. Similar results were found at the tibia. When data from five centers were combined, however, women with fracture had significantly lower total, trabecular, and cortical vBMD (2% to 7%), lower trabecular number (4% to 5%), and thinner cortices (5% to 6%) than women without fracture after adjustment for covariates. Results were similar at the radius and tibia. Similar results were observed with analysis restricted to major fragility fracture, vertebral and hip fractures, and peripheral fracture (at the radius). When focusing on osteopenic women, each SD decrease of total and trabecular vBMD was associated with a significantly increased risk of major fragility fracture (OR = 1.55 to 1.88, p data were pooled across centers and the sample size increased, we observed significant and consistent deficits in vBMD and microarchitecture independent of total hip T-score in all postmenopausal white women with fracture and in the subgroup of osteopenic women, compared to women who never had a fracture. © 2016 American

  6. Outcomes of total hip arthroplasty, as a salvage procedure, following failed internal fixation of intracapsular fractures of the femoral neck:a systematic review and meta-analysis

    OpenAIRE

    Mahmoud, Samer; Pearse, Eyiyemi; Smith, Toby; Hing, Caroline

    2016-01-01

    The management of intracapsular femoral neck fractures in independently mobile patients remains controversial. Successful fixation obviates the limitations of arthroplasty for this group of patients, however with fixation failure rates as high as 30%, the outcome of revision surgery to salvage total hip replacement (THR) must be considered. We carried out this review to determine the outcome of salvage THR and how this compares to primary THR for fracture. We performed a PRISMA compliant syst...

  7. PERENCANAAN STRATEGI DALAM UPAYA MENYELARASKAN TUJUAN ORGANISASI DAN TUJUAN KARYAWAN DENGAN PENDEKATAN TOTAL PERFORMANCE SCORECARD (Studi Kasus Departemen Internal Audit Perusahaan Minyak dan Gas Bumi

    Directory of Open Access Journals (Sweden)

    T. Yuri Zagloel puslit

    2008-01-01

    Full Text Available The competition in industry is getting harder, where companies face changes in their environment. So that organization must increase their performance and show their ability to win the competition. This tight competition makes organization has to own innovation where employees grow according to change. In the effort of improving organization performance, it must be an harmony between organization and individual objectives. This research in the oil company Indonesia aims to harmonize it based on Total Performance Scorecard (TPS. This harmonization is done through several phases with the results of a communication among organizational Balance scorecard, scorecard section and Individual Performance plan. These things become a integrated strategic planning of the company. This integrated plan means in the process of planning, it involves departments, sections, and all employees. The advantages are to make sure all employees understand the objective of their departments and their sections, whereas they involve in the process and the implementation of the strategy. Abstract in Bahasa Indonesia: Untuk menghadapi persaingan, umumnya kalangan industri terus berupaya untuk melakukan perbaikan dan peningkatan kinerja. Dalam upaya peningkatan kinerja organisasi, keselarasan antara tujuan organisasi dengan tujuan setiap individu yang ada dalam organisasi merupakan hal yang penting. Penelitian di sebuah perusahaan minyak dan gas bumi ini bertujuan untuk menyelaraskan tujuan organisasi dengan tujuan individu dengan menggunakan pendekatan Total Performance Scorecard. Pendekatan ini mempunyai kekhasan yaitu menyelaraskan tujuan organisasi dengan tujuan individu yang tergambar dalam hubungan antara Organizational Balanced Scorecard, Scorecard Section dan rencana kinerja individu. Hubungan tersebut dapat menjadi rancangan strategi yang terintegrasi bagi perusahaan, yang dalam perumusannya melibatkan pihak departemen, seksi, serta seluruh karyawan yang berada

  8. A review of the internal components of the second generation of Swedish BWRs in perspective of their importance for the total safety. A diploma work in reactor technology

    International Nuclear Information System (INIS)

    An investigation has been done of the second generation of Swedish BWRs, Barsebaeck 1 and 2, and Oskarshamn 2, concerning the vessel internals and theirs significance for the reactor safety. The purpose with this pilot study has been to produce a support for the course of action and to be a source of information for more detailed analyses of the vessel internals. A number of accident scenarios have been depicted and discussed regarding how they might occur and what the consequences might be. It is postulated that they start on account of some vessel internals failing. To be able to develop these scenarios it was necessary to collect and go through a relative large number of analyses and calculations. These have consisted of design conditions, calculation of stress and damage reports. In design conditions are included the maximum loads that a component expect to be subjected to in the course of different postulated averages. The design conditions are the input to the calculation of stress. The damage reports treat and analyse the damages that the internals have been exposed to during the years. For each scenario that has been treated, a judgement has been done about why or why not it is probable to happen. The authors do not claim to have made a probability study along the lines that are commonly accepted. The internal parts that have been the subject for the study are the core head, the feed water spargers, the steam dryers, the core shroud and the core shroud support. Below are the results with argumentations and recommendations. Core head: the core head has the behaviour that contribute most to the complexity of the scenarios. Initiators of this kind of scenarios are postulated weaknesses in the extensions of the bolts fastening the shroud head to the core shroud. A collapse of the extensions of the bolts fastening the shroud head to the core shroud will have a great impact on the reactor safety. Very likely it would lead to absent core cooling and absent

  9. Proposta do uso de pool de sangue total como controle interno de qualidade em hematologia Proposal for the use of a pool of whole blood as internal quality control in hematology

    Directory of Open Access Journals (Sweden)

    Carina Daniele Schons

    2010-06-01

    Full Text Available INTRODUÇÃO: A confiabilidade dos resultados do laboratório é garantida pela realização do controle de qualidade, que tem como funções básicas análise, pesquisa e prevenção da ocorrência de erros laboratoriais por meio de programas que abrangem tanto o controle interno quanto o externo. OBJETIVO: Propor a padronização de utilização de pool de sangue total como controle interno de qualidade no setor de hematologia. MÉTODO: Foram selecionadas amostras de sangue total, colhidas com ácido etilenodiaminotetracético (EDTA, de mesmos grupo sanguíneo e fator Rh, livres de interferentes, como hemólise, lipemia e icterícia. De um total de 30 ml de sangue total, obtiveram-se três alíquotas de 10 ml cada, às quais foram adicionados, respectivamente, 0 ml (sem adição, 1 ml e 5 ml de glicerol (conservante. As amostras foram avaliadas em contador automático ADVIA® 60. Após determinação dos valores de média e DP, todas as amostras foram avaliadas por um período de 45 dias úteis para confecção do gráfico de Levey-Jennings e verificação da estabilidade da amostra. RESULTADO E CONCLUSÃO: Podemos verificar que o pool de sangue total, preparado de acordo com a metodologia proposta, não apresenta estabilidade necessária para sua utilização, como controle interno alternativo no setor de hematologia.INTRODUCTION: The reliability of laboratory results is ensured by the implementation of quality control, which has basic functions, such as analysis, research and prevention of laboratory errors through programs that encompass both internal and external control. OBJECTIVE: To propose a standard method to use pooled whole blood as internal quality control in the Hematology division. METHOD: The selected whole blood samples were collected with EDTA, belonged to the same blood group and Rh factor and did not present interfering factors, such as hemolysis, lipemia and icterus. From a total of 30 ml of whole blood it was obtained 3

  10. The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacement

    DEFF Research Database (Denmark)

    Gossec, L; Paternotte, S; Maillefert, J F; Pelissier Combescure, Helene C; Conaghan, P G; Davis, Tamara Maree; Gunther, K-P; Hawker, G; Hochberg, M; Katz, J N; Kloppenburg, M; Lim, K; Lohmander, L S; Mahomed, N N; March, L; Pavelka, K; Punzi, L; Roos, Ewa M.; Sanchez-Riera, L; Singh, J A; Suarez-Almazor, M E; Dougados, M

    2011-01-01

    OBJECTIVE: To assess the pain and functional disability levels corresponding to an indication for total joint replacement (TJR) in hip and knee osteoarthritis (OA). METHODS: Design: International cross-sectional study in 10 countries. Patients: Consecutive outpatients with definite hip or knee OA......: In all, 1909 patients were included (1130 knee/779 hip OA). Mean age was 66.4 [standard deviation (SD) 10.9] years, 58.1% were women; 628/1130 (55.6%) knee OA and 574/779 (73.7%) hip OA patients were recommended for TJR. Although patients recommended for TJR (yes vs no) had worse symptom levels [pain......, 55.5 (95% confidence interval 54.2, 56.8) vs. 44.9 (43.2, 46.6), and functional impairment, 59.8 (58.7, 60.9) vs. 50.9 (49.3, 52.4), respectively, both P...

  11. TOTAL annual report 2003

    International Nuclear Information System (INIS)

    This 2003 annual report of the Group Total provides economical results and information of the society on the following topics: keys data, the corporate governance (Directors charter, board of directors, audit committee, nomination and remuneration committee, internal control procedures, compensation of directors and executive officers), the corporate social responsibility (environmental stewardship, the future of energy management, the safety enhancement, the human resources, ethics and local development), the investor relations, the management report, the upstream exploration and production, the downstream refining, marketing, trading and shipping, the chemicals and financial and legal information. (A.L.B.)

  12. Total process surveillance (TOPS)

    International Nuclear Information System (INIS)

    Understanding the current operating behaviour of a process or power plant is the key to maximizing the efficiency and safety of operation and the quality of the product. Early detection of plant component or sensor degradation and failure improves operating safety, product quality and plant availability. This paper describes the design and development of a Total Process Surveillance system which assimilates all the sensor information available on a plant to provide the operators with a succinct report on the status of the plant behaviour. The heart of the system is a robust model-based observer which can estimate internal plant states, and provides a residual signal with powerful fault detection and isolation features. Several results are presented which illustrate the performance of the system in detecting and isolating multiple fault scenarios in a fast reactor plant. A structure for the practical implementation of the system is described, and comments are given on its contribution to the final experimental work planned for AEA Technology's Prototype Fast Reactor (PFR). (Author)

  13. Correlates of Total Sedentary Time and Screen Time in 9–11 Year-Old Children around the World: The International Study of Childhood Obesity, Lifestyle and the Environment

    OpenAIRE

    LeBlanc, Allana G.; Katzmarzyk, Peter T.; Barreira, Tiago V.; Broyles, Stephanie T.; Chaput, Jean-Philippe; Church, Timothy S.; Fogelholm, Mikael; Harrington, Deirdre M.; Hu, Gang; Kuriyan, Rebecca; Kurpad, Anura; Lambert, Estelle V.; Maher, Carol; Maia, José; Matsudo, Victor

    2015-01-01

    Purpose Previously, studies examining correlates of sedentary behavior have been limited by small sample size, restricted geographic area, and little socio-cultural variability. Further, few studies have examined correlates of total sedentary time (SED) and screen time (ST) in the same population. This study aimed to investigate correlates of SED and ST in children around the world. Methods The sample included 5,844 children (45.6% boys, mean age = 10.4 years) from study sites in Australia, B...

  14. Total parenteral nutrition

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000177.htm Total parenteral nutrition To use the sharing features on this page, please enable JavaScript. Total parenteral nutrition (TPN) will help you or your child get ...

  15. Total Knee Replacement

    Science.gov (United States)

    ... following total knee replacement include unlimited walking, swimming, golf, driving, light hiking, biking, ballroom dancing, and other ... to the final success of your surgery. To learn more about the full value of total knee ...

  16. Total iron binding capacity

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003489.htm Total iron binding capacity To use the sharing features on this page, please enable JavaScript. Total iron binding capacity (TIBC) is a blood test to ...

  17. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available GLOBAL AP ANATOMIC TOTAL SHOULDER SYSTEM METHODIST HOSPITAL PHILADELPHIA, PA April 17, 2008 00:00:10 ANNOUNCER: ... you'll be able to watch a live global AP anatomic total shoulder surgery from Methodist Hospital ...

  18. Total well dominated trees

    DEFF Research Database (Denmark)

    Finbow, Arthur; Frendrup, Allan; Vestergaard, Preben D.

    cardinality then G is a total well dominated graph. In this paper we study composition and decomposition of total well dominated trees. By a reversible process we prove that any total well dominated tree can both be reduced to and constructed from a family of three small trees....

  19. Controversy Total War

    OpenAIRE

    Segesser, Daniel Marc

    2014-01-01

    Total war is a controversial term used in the past by politicians, publicists and military officers as well as by computer specialists and academics in the present. Since its conception by French politicians during the First World War in a time of severe crisis (1916/17), it has become a term used by historians and other academics to cover a wide array of elements when looking at wars of the past. A real total war was and is impossible. Elements of total war – total war aims, total methods of...

  20. International Clean Energy System Using Hydrogen Conversion (WE-NET). subtask 3. Conceptual design of the total system; Suiso riyo kokusai clean energy system gijutsu (WE-NET). subtask 3. Zentai system gainen sekkei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This paper describes the research result on the conceptual design of the total system for the WE-NET project in 1996. Basic conditions are as follows: solid polymer water electrolysis, hydrogen combustion turbine power generation, hydrogen transport/storage through ammonia medium, power generation scale of 1000-4000MW (2-5 yen/kWh), and transport distance of 5000-20000km between supply and consumption places. The system efficiency was estimated to be 68% and 23% at an ammonia arrival time and power sending end, respectively, and it was dependent on a transport distance, while no power generation scale. The power cost was estimated to be 7 yen/Mcal and 33 yen/kWh, respectively. The system efficiency at a sending end was lower by 15% and 2% than that of the liquid hydrogen and methanol system, while the power cost was higher by 0 and 8 yen/kWh, respectively. It was necessary for loss reduction of this ammonia system to develop a new high-efficiency ammonia synthesis process, and hydrogen separation (decomposition/refining) process. 80 figs., 52 tabs.

  1. Correlates of Total Sedentary Time and Screen Time in 9-11 Year-Old Children around the World: The International Study of Childhood Obesity, Lifestyle and the Environment.

    Directory of Open Access Journals (Sweden)

    Allana G LeBlanc

    Full Text Available Previously, studies examining correlates of sedentary behavior have been limited by small sample size, restricted geographic area, and little socio-cultural variability. Further, few studies have examined correlates of total sedentary time (SED and screen time (ST in the same population. This study aimed to investigate correlates of SED and ST in children around the world.The sample included 5,844 children (45.6% boys, mean age = 10.4 years from study sites in Australia, Brazil, Canada, China, Colombia, Finland, India, Kenya, Portugal, South Africa, the United Kingdom, and the United States. Child- and parent-reported behavioral, household, and neighborhood characteristics and directly measured anthropometric and accelerometer data were obtained. Twenty-one potential correlates of SED and ST were examined using multilevel models, adjusting for sex, age, and highest parental education, with school and study site as random effects. Variables that were moderately associated with SED and/or ST in univariate analyses (p<0.10 were included in the final models. Variables that remained significant in the final models (p<0.05 were considered correlates of SED and/or ST.Children averaged 8.6 hours of daily SED, and 54.2% of children failed to meet ST guidelines. In all study sites, boys reported higher ST, were less likely to meet ST guidelines, and had higher BMI z-scores than girls. In 9 of 12 sites, girls engaged in significantly more SED than boys. Common correlates of higher SED and ST included poor weight status, not meeting physical activity guidelines, and having a TV or a computer in the bedroom.In this global sample many common correlates of SED and ST were identified, some of which are easily modifiable (e.g., removing TV from the bedroom, and others that may require more intense behavioral interventions (e.g., increasing physical activity. Future work should incorporate these findings into the development of culturally meaningful public health

  2. Genoptraening efter total knaealloplastik

    DEFF Research Database (Denmark)

    Holm, Bente; Kehlet, Henrik

    2009-01-01

    The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty rehabilitat......The short- and long-term benefits of post-discharge physiotherapy regimens after total knee arthroplasty are debatable. A national survey including hospitals in Denmark that perform total knee arthroplasty showed a large variability in indication and regimen for post-knee arthroplasty...

  3. Totalization Data Exchange (TDEX)

    Data.gov (United States)

    Social Security Administration — The Totalization Data Exchange (TDEX) process is an exchange between SSA and its foreign country partners to identify deaths of beneficiaries residing abroad. The...

  4. Total Process Surveillance (TOPS)

    International Nuclear Information System (INIS)

    analytical redundancy is of significant importance in order to obtain the maximum amount of information as to the state of the plant. A further logical step in this theory is the accommodation of failed or damaged transducers by deriving their measurement information from the available remaining transducers. A system capable of providing a clear and improved picture of the plant's behaviour under a range of normal and off-normal operating conditions would thus be of significant economical and safety benefit. In summary: A Total Process Surveillance system is under development which can provide, in real-time, additional process information from a limited number of raw measurement signals. This is achieved by using a robust model based observer to generate estimates of the process' internal states. The observer utilises the analytical redundancy among a diverse range of transducers and can thus accommodate off-normal conditions which lead to transducer loss or damage. The modular hierarchical structure of the system enables the maximum amount of information to be assimilated from the available instrument signals no matter how diverse. This structure also constitutes a data reduction path thus reducing operator cognitive overload from a large number of varying, and possibly contradictory, raw plant signals. The TOPS system provides a structured and complete means for plant data management under both normal and off-normal operating conditions and thus will significantly assist the operator during severe accident management

  5. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... with regard to longevity of total shoulders versus hips and knees. 00:46:20 GERALD WILLIAMS, MD: ... is almost ten years younger than the average hip or knee replacement patient. But if you look ...

  6. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available GLOBAL AP ANATOMIC TOTAL SHOULDER SYSTEM METHODIST HOSPITAL PHILADELPHIA, PA April 17, 2008 00:00:10 ANNOUNCER: DePuy Orthopedics is continually advancing the standard of orthopedic patient care. In a few ...

  7. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... MD: This is Doug Boardman from Richmond, Virginia. We're here at Methodist Hospital in Philadelphia, where ... will be performing a total shoulder arthroplasty. Before we go to Dr. Williams, I'd like to ...

  8. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... you look anyplace, there's probably six or eight articles in the literature right now that have compared ... Dr. Rockwood, my friend and mentor, published an article that showed pain relief was better in totals. ...

  9. Total parenteral nutrition - infants

    Science.gov (United States)

    Total parenteral nutrition (TPN) is a method of feeding that bypasses the gastrointestinal tract. Fluids are given into a vein to ... babies. It can provide a better level of nutrition than regular intravenous (IV) feedings, which provide only ...

  10. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... We had a question with regard to physical therapy after total shoulder arthroplasty: expectations and limitations. 00: ... opposite. We don't -- we do hardly any therapy at all to reverse. With reverse patients, they ...

  11. Total 2004 results

    International Nuclear Information System (INIS)

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  12. Total Ecosystem Carbon Stock

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Total ecosystem carbon includes above- and below-ground live plant components (such as leaf, branch, stem and root), dead biomass (such as standing dead wood, down...

  13. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... And we have Dr. Song visiting us from South Korea. This patient is a 78-year-old male ... there's probably six or eight articles in the literature right now that have compared hemis to totals. ...

  14. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... be performing a total shoulder arthroplasty. Before we go to Dr. Williams, I'd like to encourage ... It's always a question about how deep we go with this osteotomy. I tend to go almost ...

  15. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available GLOBAL AP ANATOMIC TOTAL SHOULDER SYSTEM METHODIST HOSPITAL PHILADELPHIA, PA April 17, 2008 00:00:10 ANNOUNCER: DePuy Orthopedics is continually advancing the standard of orthopedic patient ...

  16. Total 2004 results

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-01

    This document presents the 2004 results of Total Group: consolidated account, special items, number of shares, market environment, adjustment for amortization of Sanofi-Aventis merger-related intangibles, 4. quarter 2004 results (operating and net incomes, cash flow), upstream (results, production, reserves, recent highlights), downstream (results, refinery throughput, recent highlights), chemicals (results, recent highlights), Total's full year 2004 results (operating and net income, cash flow), 2005 sensitivities, Total SA parent company accounts and proposed dividend, adoption of IFRS accounting, summary and outlook, main operating information by segment for the 4. quarter and full year 2004: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refined product sales by region, chemicals), Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  17. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... WILLIAMS, MD: The patients that have a total shoulder replacement will come in on their first postoperative visit and tell you their pain's gone. The hemi arthroplasty without interposition will come ...

  18. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... compared hemis to totals. Even Dr. Rockwood, my friend and mentor, published an article that showed pain ... reasonably good cortices, I get a little more aggressive, but not a lot. This is not a ...

  19. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... to longevity of total shoulders versus hips and knees. 00:46:20 GERALD WILLIAMS, MD: Well, obviously, ... ten years younger than the average hip or knee replacement patient. But if you look at the ...

  20. Total parenteral nutrition

    Science.gov (United States)

    Total parenteral nutrition (TPN) will help you or your child get nutrition from a special formula through a vein in the ... you can also eat and drink while getting nutrition from TPN. Your nurse will teach you how ...

  1. Total Grid Estimation

    OpenAIRE

    R. Kelley Pace

    1998-01-01

    This article provides a matrix representation of the adjustment grid estimator. From this representation, one can invoke the Gauss-Mrkov theorem to examine the efficiency of ordinary least squares (OLS) and the grid estimator that uses OLS estimates of the adjustments (the "plug-in" grid method). In addition, this matrix representation suggests a generalized least squares version of the grid method, labeled herin as the total grid estimator. Based on the empirical experiments, the total grid ...

  2. Total PET Recycling

    Czech Academy of Sciences Publication Activity Database

    Veselý, Václav; Punčochář, Miroslav

    Bratislava : Slovak University of Technology, 2004 - (Markoš, J.; Štefuca, V.), s. 222 ISBN 80-227-2052-6. [International Conference of Slovak Society of Chemical Engineering /31./. Tatranské Matliare (SK), 24.05.2004-28.05.2004] Institutional research plan: CEZ:AV0Z4072921 Keywords : recycling * waste management * pet Subject RIV: CI - Industrial Chemistry, Chemical Engineering

  3. Guiding light by and beyond the total internal reflection mechanism

    NARCIS (Netherlands)

    Uranus, Henri Putra

    2005-01-01

    This thesis reports a series of techniques the author has developed to model various waveguiding structures, including the conventional planar and channel waveguides working by, and the advanced structures working beyond the TIR mechanism. Hence, this thesis contains both the methods and their appli

  4. Internal Control Organization Procedure

    OpenAIRE

    Radu Dorin Lenghel

    2013-01-01

    Internal control represents the totality of policies and procedures adopted by management, which contribute: to the fulfilment of managerial objectives, to the prevention and detection of frauds or errors, to the accuracy and exhaustiveness of accounting entries, as well as to the preparation in due course of financial accounting information. Internal control represents a managerial instrument which assures the fulfilment of objectives of the entity, being an ongoing process in which administ...

  5. Total Energy Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, S

    2008-08-11

    The total energy monitor (TE) is a thermal sensor that determines the total energy of each FEL pulse based on the temperature rise induced in a silicon wafer upon absorption of the FEL. The TE provides a destructive measurement of the FEL pulse energy in real-time on a pulse-by-pulse basis. As a thermal detector, the TE is expected to suffer least from ultra-fast non-linear effects and to be easy to calibrate. It will therefore primarily be used to cross-calibrate other detectors such as the Gas Detector or the Direct Imager during LCLS commissioning. This document describes the design of the TE and summarizes the considerations and calculations that have led to it. This document summarizes the physics behind the operation of the Total Energy Monitor at LCLS and derives associated engineering specifications.

  6. A total safety management model

    International Nuclear Information System (INIS)

    In nuclear organizations, quality and safety are inextricably linked. Therefore, the search for excellence means reaching excellence in nuclear safety. The International Atomic Energy Agency, IAEA, developed, after the Chernobyl accident, the organizational approach for improving nuclear safety based on the safety culture, which requires a framework necessary to provide modifications in personnel attitudes and behaviors in situations related to safety. This work presents a Total Safety Management Model, based on the Model of Excellence of the Brazilian Quality Award and on the safety culture approach, which represents an alternative to this framework. The Model is currently under validation at the Nuclear Engineering Institute, in Rio de Janeiro, Brazil, and the results of its initial safety culture self assessment are also presented and discussed. (author)

  7. Total Cost of Ownership Considerations in Global Sourcing Processes

    OpenAIRE

    Alard, Robert; Bremen, Philipp; Oehmen, Josef; Schneider, Christian

    2010-01-01

    International audience Even within the financial crisis Global Sourcing is gaining more and more importance. Although a lot of European companies have already a long experience with international supply markets, uncertainties about the consequences and the costs related to a specific international supplier selection still remain. The Total Cost of Ownership concept is an interesting approach in order to cope with this problem. In the present paper key requirements for a Total Cost of Owner...

  8. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... AP ANATOMIC TOTAL SHOULDER SYSTEM METHODIST HOSPITAL PHILADELPHIA, PA April 17, 2008 00:00:10 ANNOUNCER: DePuy ... you don't make a bunch of small passes at the lesser tuberosity and make it a ...

  9. Total Synthesis of (-)-Cardiopetaline.

    Science.gov (United States)

    Nishiyama, Yoshitake; Yokoshima, Satoshi; Fukuyama, Tohru

    2016-05-20

    The total synthesis of (-)-cardiopetaline, an aconitine-type natural product, has been accomplished. Our synthesis involved a Wagner-Meerwein rearrangement of a sulfonyloxirane that enabled, in a single step, the construction of the bicyclo[3.2.1] system in the aconitine skeleton and effective introduction of oxygen functional groups at the appropriate positions. PMID:27166640

  10. Supravaginal eller total hysterektomi?

    DEFF Research Database (Denmark)

    Edvardsen, L; Madsen, E M

    1994-01-01

    There has been a decline in the rate of hysterectomies in Denmark in general over the last thirteen years, together with a rise in the number of supravaginal operations over the last two years. The literature concerning the relative merits of the supravaginal and the total abdominal operation is ...... indicate a reduced frequency of orgasm after the total hysterectomy compared with the supravaginal operation. When there are technical problems peroperatively with an increased urologic risk the supravaginal operation is recommended....... examined. It is concluded that the risk of developing carcinoma of the cervical stump is low, and no longer a weighty indication for the total in preference to the supravaginal hysterectomy as long as subsequent screening of the cervix is performed. At the same time it is important to inform the women......There has been a decline in the rate of hysterectomies in Denmark in general over the last thirteen years, together with a rise in the number of supravaginal operations over the last two years. The literature concerning the relative merits of the supravaginal and the total abdominal operation is...

  11. Total Cost of Ownership

    DEFF Research Database (Denmark)

    Zachariassen, Frederik

    2007-01-01

    Total Cost of Ownership (TCO), som giver et bud på, hvordan virksomheder kan opnå en bedre indsigt i, hvilke leverandører der forårsager hvilke omkostninger og dermed danne et forbedret beslutningsgrundlag for besparelser i leverandørleddet. I artiklen argumenteres først og fremmest for, hvorfor TCO er...

  12. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... to longevity of total shoulders versus hips and knees. 00:46:20 GERALD WILLIAMS, MD: Well, obviously, if you look at -- it depends upon who you put them in. First of all, the young-- the youngest patient population for joint replacement in the United States by far, by ...

  13. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... Anatomic Total Shoulder surgery, which featured the latest innovation in shoulder surgery from DePuy Orthopedics. OR-Live makes it easy for you to learn more. Just click on the "Request Information" button on your webcast screen and open the door to informed medical care. 01:21: ...

  14. "Total Deposition (TDEP) Maps"

    Science.gov (United States)

    The presentation provides an update on the use of a hybrid methodology that relies on measured values from national monitoring networks and modeled values from CMAQ to produce of maps of total deposition for use in critical loads and other ecological assessments. Additionally, c...

  15. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... put totals in unless they're under the age of 50. But as the patient gets older, ... I'll give you an example: 26-year-old juvenile rheumatoid arthritic. You can pulse-irrigate that, ...

  16. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... advancing the standard of orthopedic patient care. In a few moments, you'll be able to watch a live global AP anatomic total shoulder surgery from Methodist Hospital in Philadelphia. A revolution in shoulder orthopedics, the Global AP gives ...

  17. Total versus subtotal hysterectomy

    DEFF Research Database (Denmark)

    Gimbel, Helga; Zobbe, Vibeke; Andersen, Anna Birthe; Gluud, Christian; Ottesen, Bent S; Tabor, Ann

    2005-01-01

    The aim of this study was to compare total and subtotal abdominal hysterectomy for benign indications, with regard to urinary incontinence, postoperative complications, quality of life (SF-36), constipation, prolapse, satisfaction with sexual life, and pelvic pain at 1-year postoperative. Eighty...

  18. Anatomic Total Shoulder System

    Medline Plus

    Full Text Available ... by almost ten years, is shoulders. So by definition, the average shoulder-replacement patient is almost ten ... Anatomic Total Shoulder surgery, which featured the latest innovation in shoulder surgery from DePuy Orthopedics. OR-Live ...

  19. Total Cross Sections

    OpenAIRE

    G. GiacomelliBologna University and INFN

    2014-01-01

    The measurements of the hadron-hadron total cross sections are the first measurements performed when a new hadron accelerator opens up a new energy region; the measurements were made as function of the incoming beam momentum or c.m. energy and have often been repeated with improved accuracy and finer energy spacing.

  20. CSF total protein

    Science.gov (United States)

    CSF total protein is a test to determine the amount of protein in your spinal fluid, also called cerebrospinal fluid (CSF). ... The normal protein range varies from lab to lab, but is typically about 15 to 60 mg/dL. Note: mg/dL = ...

  1. Total 2004 annual report

    International Nuclear Information System (INIS)

    This annual report of the Group Total brings information and economic data on the following topics, for the year 2004: the corporate governance, the corporate social responsibility, the shareholder notebook, the management report, the activities, the upstream (exploration and production) and downstream (refining and marketing) operating, chemicals and other matters. (A.L.B.)

  2. Total Quality Management Seminar.

    Science.gov (United States)

    Massachusetts Career Development Inst., Springfield.

    This booklet is one of six texts from a workplace literacy curriculum designed to assist learners in facing the increased demands of the workplace. The booklet contains seven sections that cover the following topics: (1) meaning of total quality management (TQM); (2) the customer; (3) the organization's culture; (4) comparison of management…

  3. Total Quality Management Simplified.

    Science.gov (United States)

    Arias, Pam

    1995-01-01

    Maintains that Total Quality Management (TQM) is one method that helps to monitor and improve the quality of child care. Lists four steps for a child-care center to design and implement its own TQM program. Suggests that quality assurance in child-care settings is an ongoing process, and that TQM programs help in providing consistent, high-quality…

  4. International arbejdsdeling

    DEFF Research Database (Denmark)

    Henten, Anders

    1998-01-01

    Article dealing with the implications of informátion and communication technologies on the international division of labour.......Article dealing with the implications of informátion and communication technologies on the international division of labour....

  5. International safeguards

    International Nuclear Information System (INIS)

    The following topics are covered in this chapter: basis for international safeguards; basis for applying international safeguards in US facilities; application of international safeguards at the facility level; and example of application of international safeguards at a low-enriched uranium fuel fabrication facility including material balance area structure and key measurement points, inspection activities, auditing operator's measurement system, verifying nuclear material, containment and surveillance measures, and inspector's conclusions

  6. Total 2003 Results

    International Nuclear Information System (INIS)

    This document presents the 2003 results of Total Group: consolidated account, special items, number of shares, market environment, 4. quarter 2003 results, full year 2003 results, upstream (key figures, proved reserves), downstream key figures, chemicals key figures, parent company accounts and proposed dividends, 2004 sensitivities, summary and outlook, operating information by segment for the 4. quarter and full year 2003: upstream (combined liquids and gas production by region, liquids production by region, gas production by region), downstream (refinery throughput by region, refined product sales by region, chemicals), impact of allocating contribution of Cepsa to net operating income by business segment: equity in income (loss) and affiliates and other items, Total financial statements: consolidated statement of income, consolidated balance sheet (assets, liabilities and shareholder's equity), consolidated statements of cash flows, business segments information. (J.S.)

  7. Total - annual report 2005

    International Nuclear Information System (INIS)

    This annual report presents the activities and results of TOTAL S.A., french society on oil and gas. It deals with statistics, the managers, key information on financial data and risk factors, information on the Company, unresolved Staff Comments, employees, major Shareholders, consolidated statements, markets, security, financial risks, defaults dividend arrearages and delinquencies, controls and procedures, code of ethics and financial statements. (A.L.B.)

  8. Total Synthesis of Millingtonine.

    Science.gov (United States)

    Brown, Patrick D; Lawrence, Andrew L

    2016-07-11

    Millingtonine is a glycosidic alkaloid that exists as a pair of pseudo-enantiomeric diastereomers. Consideration of the likely biosynthetic origins of this unusual natural product has resulted in the development of a seven-step total synthesis. Results from this synthetic work provide evidence in support of a proposed network of biosynthetic pathways that can account for the formation of several phenylethanoid natural products. PMID:27249628

  9. Total synthesis of teixobactin.

    Science.gov (United States)

    Jin, Kang; Sam, Iek Hou; Po, Kathy Hiu Laam; Lin, Du'an; Ghazvini Zadeh, Ebrahim H; Chen, Sheng; Yuan, Yu; Li, Xuechen

    2016-01-01

    To cope with the global bacterial multidrug resistance, scientific communities have devoted significant efforts to develop novel antibiotics, particularly those with new modes of actions. Teixobactin, recently isolated from uncultured bacteria, is considered as a promising first-in-class drug candidate for clinical development. Herein, we report its total synthesis by a highly convergent Ser ligation approach and this strategy allows us to prepare several analogues of the natural product. PMID:27484680

  10. Total synthesis of ochnaflavone

    OpenAIRE

    Monica M. Ndoile; van Heerden, Fanie R

    2013-01-01

    The first total syntheses of ochnaflavone, an asymmetric biflavone consisting of apigenin and luteolin moieties, and the permethyl ether of 2,3,2'',3''-tetrahydroochnaflavone have been achieved. The key steps in the synthesis of ochnaflavone were the formation of a diaryl ether and ring cyclization of an ether-linked dimeric chalcone to assemble the two flavone nuclei. Optimal experimental conditions for the oxidative cyclization to form ochnaflavone were established.

  11. Total synthesis of ochnaflavone

    Directory of Open Access Journals (Sweden)

    Monica M. Ndoile

    2013-07-01

    Full Text Available The first total syntheses of ochnaflavone, an asymmetric biflavone consisting of apigenin and luteolin moieties, and the permethyl ether of 2,3,2'',3''-tetrahydroochnaflavone have been achieved. The key steps in the synthesis of ochnaflavone were the formation of a diaryl ether and ring cyclization of an ether-linked dimeric chalcone to assemble the two flavone nuclei. Optimal experimental conditions for the oxidative cyclization to form ochnaflavone were established.

  12. Boosting Total Relationship Marketing

    OpenAIRE

    Aykut, Arslan

    2008-01-01

    This paper explores the track of marketing, by referring to the literature, through the advancements in digitalized technological systems particularly Information Technologies (IT), the emergence of a more broadly educated and more discerning consumer with increasing discretionary spending and purchasing power, the adoption of Total Quality Management (TQM) as the biggest competitive issue of 1990s, the growth of the service economy, the increase of competitive intensity and its impact on cus...

  13. Total Logistic Plant Solutions

    Directory of Open Access Journals (Sweden)

    Dusan Dorcak

    2016-02-01

    Full Text Available The Total Logistics Plant Solutions, plant logistics system - TLPS, based on the philosophy of advanced control processes enables complex coordination of business processes and flows and the management and scheduling of production in the appropriate production plans and planning periods. Main attributes of TLPS is to create a comprehensive, multi-level, enterprise logistics information system, with a certain degree of intelligence, which accepts the latest science and research results in the field of production technology and logistics. Logistic model of company understands as a system of mutually transforming flows of materials, energy, information, finance, which is realized by chain activities and operations

  14. Total Synthesis of Teixobactin.

    Science.gov (United States)

    Giltrap, Andrew M; Dowman, Luke J; Nagalingam, Gayathri; Ochoa, Jessica L; Linington, Roger G; Britton, Warwick J; Payne, Richard J

    2016-06-01

    The first total synthesis of the cyclic depsipeptide natural product teixobactin is described. Synthesis was achieved by solid-phase peptide synthesis, incorporating the unusual l-allo-enduracididine as a suitably protected synthetic cassette and employing a key on-resin esterification and solution-phase macrolactamization. The synthetic natural product was shown to possess potent antibacterial activity against a range of Gram-positive pathogenic bacteria, including a virulent strain of Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus (MRSA). PMID:27191730

  15. Total quality accounting

    Directory of Open Access Journals (Sweden)

    Andrijašević Maja

    2008-01-01

    Full Text Available The focus of competitive "battle" shifted from the price towards non-price instruments, above all, towards quality that became the key variable for profitability increase and achievement of better comparative position of a company. Under such conditions, management of a company, which, according to the established and certified system of total quality, strives towards achieving of a better market position, faces the problem of quality cost measurement and determination. Management, above all, cost accounting can help in solving of this problem, but the question is how much of its potential is being used for that purpose.

  16. Total Factbook 2003

    International Nuclear Information System (INIS)

    This report presents the activities and results of the Group Total-Fina-Elf for the year 2003. It brings information and economic data on the following topics: the corporate and business; the upstream activities with the reserves, the costs, standardized measure and changes of discounted future net cash flow,oil and gas acreage, drilling, liquefied natural gas, pipelines; downstream activities with refining and marketing maps, refinery, petroleum products, sales, retail gasoline outlets; chemicals with sales and operating income by sector, major applications, base chemicals and polymers, intermediates and performance polymers. (A.L.B.)

  17. Total 2004 fact book

    International Nuclear Information System (INIS)

    This report presents the activities and results of the Group Total-Fina-Elf for the year 2004. It brings information and economic data on the following topics: the corporate and business; the upstream activities with the reserves, the costs, standardized measure and changes of discounted future net cash flow,oil and gas acreage, drilling, liquefied natural gas, pipelines; downstream activities with refining and marketing maps, refinery, petroleum products, sales, retail gasoline outlets; chemicals with sales and operating income by sector, major applications, base chemicals and polymers, intermediates and performance polymers. (A.L.B.)

  18. Total quality is people

    International Nuclear Information System (INIS)

    Confronted by changing market conditions and increased global competition, in 1983 the Commercial Nuclear Fuel Division (CNFD) of Westinghouse Electric embarked on an ambitious plan to make total quality the centerpiece of its long-term business strategy. Five years later, the division's efforts in making continuous quality improvement a way of life among its more than 2,000 employees gained national recognition when it was named a charter recipient of the Malcolm Baldridge National Quality Award. What CNFD achieved during the 1980s was a cultural transformation, characterized by an empowered work force committed to a common vision. The company's quality program development strategy is described

  19. Immediate total tooth replacement.

    Science.gov (United States)

    Garber, D A; Salama, M A; Salama, H

    2001-03-01

    Successful implant placement at the time of extraction has been documented. Implant placement at the time of extraction was initially performed as a two-stage procedure often with barrier membranes and sophisticated second-stage surgical uncoverings. The authors describe the next generation of this technique, including atraumatic tooth removal with simultaneous root form, implant placement, and temporization at one appointment. This technique of "Immediate Total Tooth Replacement" allows for the maintenance of the bony housing and soft-tissue form that existed before extraction, while at the same time establishing a root form anchor in the bone for an esthetic restoration. PMID:11913258

  20. Total Synthesis of (-)-Daphenylline.

    Science.gov (United States)

    Yamada, Ryosuke; Adachi, Yohei; Yokoshima, Satoshi; Fukuyama, Tohru

    2016-05-10

    Total synthesis of (-)-daphenylline, a hexacyclic Daphniphyllum alkaloid, was achieved. Construction of the tricyclic DEF ring system was initiated by asymmetric Negishi coupling followed by an intramolecular Friedel-Crafts reaction. Installation of a side chain onto the tricyclic core was carried out through Sonogashira coupling, stereocontrolled Claisen rearrangement by taking advantage of the characteristic conformation of the tricyclic DEF core, and the stereoselective alkylation of a lactone. After the introduction of a glycine unit, the ABC ring system was stereoselectively constructed through intramolecular cycloaddition of the cyclic azomethine ylide. PMID:27062676

  1. Internal branding

    OpenAIRE

    Rai, Anu; omanga, josphat

    2015-01-01

    The project report provides an insight into internal branding of two different leading firms – Coca-Cola and Google. The aim of this project report is to study how these two companies use internal branding to promote or build brand performance of the company. This report follows a qualitative research method. The report is deductive in nature and hence, it is guided by the literatures of internal branding. The project report conducted research on brand identity, brand commitment and brand...

  2. International marketing

    OpenAIRE

    Cateora, Philip R.

    2012-01-01

    The international marketplace has been transformed in recent years by shifts in trading patterns and practices. These changes have been reinforced by new technologies and evolving economic relationships. This paper is an attempt to integrate these developments into the burgeoning literature on international marketing as well as recent research findings. The research emphasis within the subject has evolved alongside changes in the stress given to key aspects of international trade. The preoccu...

  3. Internal audit

    OpenAIRE

    Topor, Peter

    2011-01-01

    Master's thesis is referring the importance and requirement of internal audit in middle sized enterprises. It summarizes theoretical basis for the implementation of internal audit's profession and its legislative environment. Thesis is focused on the analysis of the processes of administration and record keeping of leasing agreements in corporation. Based on the analysis, solutions and measures concerning internal controls are proposed. Goal of the Master's thesis is to refer the importance o...

  4. CNN International

    OpenAIRE

    Swann, David

    2013-01-01

    Dr David Swann interviewed by CNN International for a special programme series profiling international designers- 90 seconds vignette showcased innovative solutions from around the world. A theme week on CNN International and CNN.com concluded with a half hour program special in September. The campaign was played to CNN’s television and online audiences with a global reach of 2 billion in 200 countries and 271 million households around the world.

  5. International Perspectives.

    Science.gov (United States)

    Allen, Kenn; Habermann, Ulla; Chowdhury, Omar Faruque; Guerra, Iraida Manzanilla

    1998-01-01

    Includes "Introduction to International Perspectives" (Allen); "Volunteerism in the Welfare State: The Case of Denmark" (Habermann); "Grassroots Organizing in Bangladesh" (Chowdhury); and "Volunteerism in Latin America" (Guerra). (SK)

  6. Total synthesis of atropurpuran.

    Science.gov (United States)

    Gong, Jing; Chen, Huan; Liu, Xiao-Yu; Wang, Zhi-Xiu; Nie, Wei; Qin, Yong

    2016-01-01

    Due to their architectural intricacy and biological significance, the synthesis of polycyclic diterpenes and their biogenetically related alkaloids have been the subject of considerable interest over the last few decades, with progress including the impressive synthesis of several elusive targets. Despite tremendous efforts, conquering the unique structural types of this large natural product family remains a long-term challenge. The arcutane diterpenes and related alkaloids, bearing a congested tetracyclo[5.3.3.0(4,9).0(4,12)]tridecane unit, are included in these unsolved enigmas. Here we report a concise approach to the construction of the core structure of these molecules and the first total synthesis of (±)-atropurpuran. Pivotal features of the synthesis include an oxidative dearomatization/intramolecular Diels-Alder cycloaddition cascade, sequential aldol and ketyl-olefin cyclizations to assemble the highly caged framework, and a chemoselective and stereoselective reduction to install the requisite allylic hydroxyl group in the target molecule. PMID:27387707

  7. Total organic carbon analyzer

    Science.gov (United States)

    Godec, Richard G.; Kosenka, Paul P.; Smith, Brian D.; Hutte, Richard S.; Webb, Johanna V.; Sauer, Richard L.

    1991-01-01

    The development and testing of a breadboard version of a highly sensitive total-organic-carbon (TOC) analyzer are reported. Attention is given to the system components including the CO2 sensor, oxidation reactor, acidification module, and the sample-inlet system. Research is reported for an experimental reagentless oxidation reactor, and good results are reported for linearity, sensitivity, and selectivity in the CO2 sensor. The TOC analyzer is developed with gravity-independent components and is designed for minimal additions of chemical reagents. The reagentless oxidation reactor is based on electrolysis and UV photolysis and is shown to be potentially useful. The stability of the breadboard instrument is shown to be good on a day-to-day basis, and the analyzer is capable of 5 sample analyses per day for a period of about 80 days. The instrument can provide accurate TOC and TIC measurements over a concentration range of 20 ppb to 50 ppm C.

  8. Total ankle joint replacement.

    Science.gov (United States)

    2016-02-01

    Ankle arthritis results in a stiff and painful ankle and can be a major cause of disability. For people with end-stage ankle arthritis, arthrodesis (ankle fusion) is effective at reducing pain in the shorter term, but results in a fixed joint, and over time the loss of mobility places stress on other joints in the foot that may lead to arthritis, pain and dysfunction. Another option is to perform a total ankle joint replacement, with the aim of giving the patient a mobile and pain-free ankle. In this article we review the efficacy of this procedure, including how it compares to ankle arthrodesis, and consider the indications and complications. PMID:26868932

  9. Total quality at source

    International Nuclear Information System (INIS)

    The Total Quality at Source philosophy is based on optimizing the effectiveness of people in achieving ZERO-DEFECT results. In this paper a philosophy of what, I have come to perceive, it takes to get people to perform to the very best of their abilities and thereby achieve the best results they can, is presented. In the examples I shall describe I have played an instrumental role since it has become my belief that any job can always be done better provided that the people doing it can themselves become convinced that they can do better. Clearly there are many ideas on how to do this. The philosophy that I am presenting in this paper is based on my own experience, where I have both participated and observed it being applied; its effectiveness may be judged by the results. (author)

  10. Total Integrative Evolutionary Communication

    DEFF Research Database (Denmark)

    Nedergaard Thomsen, Ole; Brier, Søren

    2014-01-01

    and, on the other, Peircean biosemiotics. According to Cybersemiotics, language is primarily a creative process of total integrative evolutionary communication. It comprises three evolutionary stages: (1) biological reflexive languaging (the reflexive foundation of social coordination), (2......). In this inclusive hierarchy language games subsume the other stages, and thus human evolutionary communication is primarily a symbolic-conventional practice. It is intertwined with the practice of living, that is, with different life forms, including other forms of semiotic behavior. Together they form a coherent...... biological and socio-cultural practice. The basic “molecule” of the cybersemiotic model of human communication is a dyad between two linguistic cyborgs, alias natural language users. Single human communicators are thus “atoms”. They are hybrids between nature and nurture, manipulating all sorts...

  11. Dosimetry of total body irradiation

    International Nuclear Information System (INIS)

    In the treatment of disseminated malignancies an improvement in the curability and reduction of complication rates require high precision total body irradiation (TBI) and correct reporting of relevant treatment parameters. Optimal TBI dosimetry is the basis. Radiooncological and radiobiological requirements as well as the special physical situation have to be considered. To review the efforts of medical physicists, highlights from TBI workshops and publications are summarized. Additionally, dosimetric data from 34 European radiooncological centres contributing to the recent ESTRO inquiry on TBI are analysed. The topics are: absorbed dose and dose monitor calibration, determination of absolute and relative doses, dose ratios, attenuation data and heterogeneity corrections; TBI dose calculation methods regarding patient position, beam incidence, body shape and thickness, lung size and density; methods of TBI treatment planning including calculated dose modification and of TBI quality assurance. In conclusion, the following recommendations can be given: TBI dosimetry shall be performed under TBI conditions, close to the real treatment situation. The absorbed dose to water must be determined. The dose monitor should be calibrated against dose measurements at the centre of a water equivalent phantom of TBI equivalent size and typical thickness. Photon fluence profiles have to be measured with small phantoms. Influences on the local dose must be investigated systematically. A reproducible AP/PA TBI technique should be used. The TBI dose shall be specified to mid-abdomen and reported in units of gray. The single and total dose and the dose rate to the lungs, the number of fractions and the treatment time schedule must be stated. In vivo dosimetry is required if non-reliable TBI techniques are used. An international TBI dosimetry intercomparison could assist these efforts to improve the treatment of acute leukaemia. (author). 89 refs, 3 figs, 13 tabs

  12. International Curriculums.

    Science.gov (United States)

    Neal, Larry L.

    This workshop presentation on international curriculums in the field of parks, recreation, leisure, cultural services, and travel/tourism comments that the literature is replete with articles addressing what the field is about, but not about curriculum issues, models, and structure. It reports an international survey of 12 college educators…

  13. International indsats

    DEFF Research Database (Denmark)

    Sachs, Therese

    En analyse af Beredskabsstyrelsens internationale engagement og muligheder for international indsats fremover. Forslag til struktur logistisk og materielt samt til udvikling af personel-kompetencer......En analyse af Beredskabsstyrelsens internationale engagement og muligheder for international indsats fremover. Forslag til struktur logistisk og materielt samt til udvikling af personel-kompetencer...

  14. International skatteret

    DEFF Research Database (Denmark)

    Winther-Sørensen, Niels; Wittendorff, Jens

    1996-01-01

    De seneste 6 måneders udvikling indenfor international skatteret beskrives. NW-S har skrevet artiklens afsnit om udvalgte afgørelser og om EU-skatteret.......De seneste 6 måneders udvikling indenfor international skatteret beskrives. NW-S har skrevet artiklens afsnit om udvalgte afgørelser og om EU-skatteret....

  15. International Specialization

    DEFF Research Database (Denmark)

    Kleindienst, Ingo; Geisler Asmussen, Christian; Hutzschenreuter, Thomas;

    2012-01-01

    Whether and how international diversification and cross-border arbitrage affects firm performance remains one of the major unresolved research questions in the strategy and international business literatures. We propose that knowing how much a firm has internationally diversified tells us very...... little about performance implications, if we do not know, and do not ask, how the firm has diversified. Therefore, building on the two broad arguments of operating flexibility and location-specific commitment, we develop a theoretical framework that focuses on the extent to which a firm's international...... arbitrage strategy is characterized by specialization versus replication and argue that these different strategies may have differential impact on profitability and risk reduction. Developing a sophisticated measure of international specialization and using a unique panel data set of 92 German MNEs to test...

  16. PRIVATE EQUITY INVESTING AND TOTAL QUALITY - UPDATED

    Directory of Open Access Journals (Sweden)

    Nikola Stefanovic

    2013-03-01

    Full Text Available Private equity funds invest money into companies and, in return, receive stakes in the companies' equity, thus becoming the partners who share the business risk. Because of that, private equity funds increase the value of their portfolio companies, by, among other things, improving their internal processes and strengthening their market positions. While doing that, private equity funds place a special emphasis on the implementation of the total quality. In order to do that, they focus on the three key elements for the successful implementation of the total quality: strategy-based organization, focus on consumers, and obsession with quality.

  17. Total disc replacement.

    Science.gov (United States)

    Vital, J-M; Boissière, L

    2014-02-01

    Total disc replacement (TDR) (partial disc replacement will not be described) has been used in the lumbar spine since the 1980s, and more recently in the cervical spine. Although the biomechanical concepts are the same and both are inserted through an anterior approach, lumbar TDR is conventionally indicated for chronic low back pain, whereas cervical TDR is used for soft discal hernia resulting in cervicobrachial neuralgia. The insertion technique must be rigorous, with precise centering in the disc space, taking account of vascular anatomy, which is more complex in the lumbar region, particularly proximally to L5-S1. All of the numerous studies, including prospective randomized comparative trials, have demonstrated non-inferiority to fusion, or even short-term superiority regarding speed of improvement. The main implant-related complication is bridging heterotopic ossification with resulting loss of range of motion and increased rates of adjacent segment degeneration, although with an incidence lower than after arthrodesis. A sufficiently long follow-up, which has not yet been reached, will be necessary to establish definitively an advantage for TDR, particularly in the cervical spine. PMID:24412045

  18. First Total Synthesis of Gliomasolide C and Formal Total Synthesis of Sch-725674.

    Science.gov (United States)

    Seetharamsingh, B; Khairnar, Pankaj V; Reddy, D Srinivasa

    2016-01-01

    Syntheses of two 14-membered macrolides Sch-725674 and Gliomasolide C are described here. The first total synthesis of Gliomasolide C, the short synthesis of Sch-725674, and regioselective Wacker oxidation of internal olefin are the highlights of this disclosure. In addition, a key macrocycle with orthogonal functionalities was designed and synthesized on a gram scale for the generation of analogues. PMID:26633579

  19. Total quality management

    OpenAIRE

    Цветкова, Наталья

    1993-01-01

    В статье рассматриваются пути улучшения качества образования вообще и лингвистического образования в частности посредством использования системы качества Total Quality Management. Охарактеризованы ее четыре этапа - планирование, управление, обеспечение и улучшение. Анализируются основные направления использования системы качества в обучении иностранному языку....

  20. Minimally Invasive Total Knee Arthroplasty

    Medline Plus

    Full Text Available ... central point, allowing its full rotation into both internal and external rotation, I don't have to ... base plate just a bit to allow maximum internal and external rotation without hitting the stops, we ...

  1. Juris International

    CERN Document Server

    A database on international trade law aimed at lawyers and legal counsel in developing and transition economies. Juris International is a multilingual collection (English, Spanish, and French) of legal information on international trade. Juris International aims to facilitate and reduce the work involved in research for business lawyers, advisers and in-house counsel, and state organizations in developing nd transition economies, by providing access to texts which have often been difficult to obtain. Its objective is to gather a large quantity of basic information at one site (favoring complete legal texts), without the need to send for the information, and consequently without excessive communication costs for users who d benefit from an efficient and cheap telecommunications network.

  2. Internal Bleeding

    Science.gov (United States)

    ... 2 Diabetes, Heart Disease a Dangerous Combo Are 'Workaholics' Prone to OCD, Anxiety? ALL NEWS > Resources First ... pelvis, that are broken. Initially, internal bleeding may cause no symptoms, although an injured organ that is ...

  3. International Health

    Science.gov (United States)

    ... create refugee populations with immediate and long-term health problems. Some of the major diseases currently affecting ... also an international problem which can affect people's health. Many countries and health organizations are working together ...

  4. Internal marketing

    OpenAIRE

    Potter, Ned

    2012-01-01

    This chapter from The Library Marketing Toolkit focuses on Internal stakeholders. They often hold the purse-strings to our libraries, so marketing successfully to them is absolutely essential. The first part of this chapter covers language, telling stories, using statistics, marketing upwards and communicating your message well. The second part covers marketing with internal stakeholders, such as a parent company within whose branding guidelines you must promote the library, or marketing as p...

  5. International oil law

    International Nuclear Information System (INIS)

    The 1973 energy crisis demonstrated that the international petroleum industry is not totally free. Very often it has been the object of an organization, even during the domination of international oil companies which have established a petroleum international system with a system of concession rights. This system is based on an oligopolistic structure which had the characteristics of a monopoly. This vertically integrated structure of the world petroleum industry during the 1920-1950 era was more or less locked up by the system of concessions. The incompatibility of this system of excessively long concession contracts with the economical development needs of oil exporting countries has led to their abolishment. They have been replaced by new agreements. As soon as the creation of stable and permanent international oil organizations (OPEC, OAPEC, IEA), an institutional right has been established which has generated international rights and principles governing the contractual relations between oil exporting and oil importing countries. This international petroleum right is both original and specific, it is evolutive, contractual and normative. (J.S.)

  6. Hardness Results for Total Rainbow Connection of Graphs

    Directory of Open Access Journals (Sweden)

    Chen Lily

    2016-05-01

    Full Text Available A total-colored path is total rainbow if both its edges and internal vertices have distinct colors. The total rainbow connection number of a connected graph G, denoted by trc(G, is the smallest number of colors that are needed in a total-coloring of G in order to make G total rainbow connected, that is, any two vertices of G are connected by a total rainbow path. In this paper, we study the computational complexity of total rainbow connection of graphs. We show that deciding whether a given total-coloring of a graph G makes it total rainbow connected is NP-Complete. We also prove that given a graph G, deciding whether trc(G = 3 is NP-Complete.

  7. Total Knee Replacement for Women

    Medline Plus

    Full Text Available ... ll be moderating a Zimmer Gender Solutions total knee, performed by my partner, Dr. Ken Gustke. At ... I’m going to be doing a total knee replacement utilizing the Gender Flex implants on a ...

  8. Transparency International

    NARCIS (Netherlands)

    Hulten, van M. (Michel)

    2009-01-01

    Established in 1993, Transparency International (TI) defines itself as “the global civil society organization leading the fight against corruption, that brings people together in a powerful worldwide coalition to end the devastating impact of corruption on men, women and children around the wo

  9. International safeguards

    International Nuclear Information System (INIS)

    Since the start of the post-war era, international safeguards were considered essential to ensure that nuclear materials should not be diverted to unauthorised uses. In parallel, it was proposed to set up an international atomic energy agency within the United Nations through which international cooperation in nuclear matters would be channelled and controlled. Created in 1957, the IAEA was authorized to administer safeguards in connection with any assistance it provided as well as at the request of Member State and of any party to bilateral or multilateral arrangements in its ambit. Today, there are two international treaties requiring that its parties should accept Agency safeguards unilaterally, the Latin America Tlatelolco Treaty of 1967, and the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), operative since 1970, which requires in particular that non-nuclear weapon states should accept Agency safeguards on its peaceful nuclear activities. Thus while NPT covers peaceful nuclear activities indiscriminately in a country, the Agency's original safeguards system is applied according to specific agreements and to given facilities. A basic conflict has now emerged between commercial interests and the increasing wish that transfer of nuclear equipment and know-how should not result in proliferation of military nuclear capacity; however, serious efforts are currently in progress to ensure universal application of IAEA safeguards and to develop them in step with the uses of nuclear energy. (N.E.A.)

  10. International Standards.

    Science.gov (United States)

    Havard-Williams, Peter

    1982-01-01

    Discussion of standardization on an international scale for resource sharing--cooperation, coordination, interlibrary loans, cooperative acquisition and cataloging--focuses on a definition of standards; the development of standards for cataloging; public, school, and university libraries; and library education. A 60-item bibliography is included.…

  11. Ascott International

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    "Heart-to-Heart" Charity Event for Hearing-Impaired Children in Beijing On June 12, Ascott International North China held a "heart-to-heart" charity event for hearing-impaired children in the Heritage Room at the Ascott Beijing.

  12. International librarianship

    OpenAIRE

    Hopkinson, Alan

    2011-01-01

    Librarianship is international and librarians can go to other countries promoting what we do in Europe with funding from ERASMUS or TEMPUS, EU programmes, and with that and other funds such as Commonwealth fellowships, librarians can be invited from overseas to learn from us in the UK

  13. Minimally Invasive Total Knee Arthroplasty

    Medline Plus

    Full Text Available ... central point, allowing its full rotation into both internal and external rotation, I don't have to worry about ... base plate just a bit to allow maximum internal and external rotation without hitting the stops, we can adjust ...

  14. Teaching International Law: Concepts in International Relations

    Science.gov (United States)

    Starbird, Caroline; Pettit, Jenny; Singleton, Laurel

    2004-01-01

    This book is designed to introduce students to public international law. Topics covered include international public organizations, such as the United Nations and World Trade Organization, international courts, international human rights law, international trade law, and international environmental law. The goal of each study is to examine how…

  15. International Trade

    OpenAIRE

    Bonfiglioli, Alessandra

    2011-01-01

    International trade has been one of the most dynamic sub-fields of economics in recent years, with exciting new work on trade under imperfect competition as well as important extensions of existing models. This two volume set of readings synthesizes these contributions, including some rare classic articles as well as a representative selection of the best modern work. The editor’s introductions to the volumes, which contain extensive bibliographies, put the readings in perspective and in the ...

  16. INTERNAL ENVELOPES

    CERN Multimedia

    Mail Office

    2001-01-01

    Internal mail envelopes often finish up in large piles in certain offices, thus creating a shortage for other users of the mail service, who would be grateful if everyone with an unused stock could deposit them in their mail box, after attaching them together with an elastic band or piece of string. The messengers will then collect them so that the Mail Office can put them back in circulation. Thank you for your understanding and collaboration.

  17. Fostering internalization

    DEFF Research Database (Denmark)

    Baernholdt, Marianne; Drake, Emily; Maron, Frederic;

    2013-01-01

    Aim: This paper describes the development, implementation and evaluation of a semester-long exchange program between two Bachelor of Science in Nursing programs in the USA and Denmark. Background: Nurses globally need to provide culturally sensitive care for an ethnically diverse population. Comp......, flexibility and open communication are key components when setting up a 360 degrees exchange program. Keywords: Cultural Competence, Exchanges, International Collaboration, Undergraduate Education...

  18. International cooperation

    International Nuclear Information System (INIS)

    Europe is certainly the part of the world where the largest number of international arrangements have been established for dealing with international cooperation in cases of major oil spills at sea. Let me list the most important of these multilateral arrangements: Bonn Agreement: covers the North Sea Contracting Parties: riparian states and the EEC Barcelona Convention: (protocol for emergency situations) covers the Mediterranean Sea Contracting Parties: riparian states and the EEC; Helsinki Convention: covers the Baltic Sea Contracting Parties: riparian states and (soon) the EEC; Lisbon Agreement: covers the NE Atlantic Contracting Parties: France, Spain, Portugal, Morocco and the EEC; Community Action Plan: covers the whole community waters; EEC; Members States participate in this plan. It should be underlined that, in addition to these large multilateral agreements a number of bilateral or trilateral arrangements have been set up, such as the Copenhagen Agreement, Denger Plan, Manche Plan, etc. The Commission involvement in these international frameworks is very important: as an example, it is presently chairing the Bonn Agreement Contracting Parties meeting. In addition, being the only contracting party to all these agreements, it is able to play a unique role of coordination and information to avoid duplications and contradictions. Having given this overview, I would now focus on the Community Action Plan

  19. Internal corrosion

    Energy Technology Data Exchange (ETDEWEB)

    Joosten, M. [ConocoPhillips, Bartlesville, OK (United States); Anderson, W. [Spectra Energy Transmission, Vancouver, BC (Canada)

    2007-07-01

    Working Group 11 identified internal corrosion issues in both upstream and downstream oil and gas pipelines and suggested ways to address them through integrity management, modeling, and monitoring. Three sessions were held in an effort to provided a better understanding between integrity professionals engaged in different aspects of pipeline management. Opportunities for reducing cost or improving integrity performance of the whole system were also identified. It was determined that management support is needed in order to monitor and mitigate internal corrosion of pipelines. The role of regulations in ensuring pipeline integrity was also discussed along with rules for pigging and batching of inhibitors. In-line inspections have identified under-deposit corrosion and solids/water deposition as two key problems facing pipeline operators. It was noted that an internal corrosion course offered by the National Association of Corrosion Engineers (NACE) is being well attended and is providing worthwhile training. Other issues discussed by this working group were: bacteria with upstream problems; effects of carbon dioxide, hydrogen sulphide and partial pressures on corrosion; and, procedures and guidelines to maintain clean pipelines. tabs., figs.

  20. Vascular injuries during total hip revision

    International Nuclear Information System (INIS)

    Although most patients undergoing a revision total hip replacement (THR) will have an uneventful procedure, in others the potential of serous vascular injuries is real. Migrating prosthesis or excessive cement may be in compromising positions adjacent or adherent to vessels and pose a particular danger at surgery with inadvertent lacerations of vessels such as the internal and external iliac arteries. In out study of 20 patients with THR, CT with two-dimensional reconstructions is used to define vessel position. In eight of these patients, the hip prosthesis or displaced cement lies within 5 mm of major vessels. In patients with dislocation of the acetabular cup, the potential of vascular injury is highest

  1. Asymptotic Behaviour of Total Generalised Variation

    KAUST Repository

    Papafitsoros, Konstantinos

    2015-01-01

    © Springer International Publishing Switzerland 2015. The recently introduced second order total generalised variation functional TGV2 β,α has been a successful regulariser for image processing purposes. Its definition involves two positive parameters α and β whose values determine the amount and the quality of the regularisation. In this paper we report on the behaviour of TGV2 β,α in the cases where the parameters α, β as well as their ratio β/α becomes very large or very small. Among others, we prove that for sufficiently symmetric two dimensional data and large ratio β/α, TGV2 β,α regularisation coincides with total variation (TV) regularization

  2. An unusual case of total ophthalmoplegia

    Directory of Open Access Journals (Sweden)

    Chowdhury Ravindra

    2009-01-01

    Full Text Available An eight-year-old male child presented with drooping of the left eyelid with a history of penetrating injury of hard palate by an iron spoon seven days ago, which had already been removed by the neurosurgeon as the computed tomography scan revealed a spoon in the left posterior ethmoid and sphenoid bone penetrating into the middle cranial fossa. On examination, visual acuity was 20/20 in each eye and left eye showed total ophthalmoplegia. Oral cavity revealed a hole in the left lateral part of the hard palate. We managed the case with tapering dose of systemic prednisolone. The total ophthalmoplegia was markedly improved in one month. Cases of foreign bodies in the orbit with intracranial extension are not unusual, but the path this foreign body traveled through the hard palate without affecting the optic nerve, internal carotid artery or cavernous sinus makes an interesting variation.

  3. Regular Totally Separable Sphere Packings

    OpenAIRE

    Reid, Samuel

    2015-01-01

    The topic of totally separable sphere packings is surveyed with a focus on regular constructions, uniform tilings, and contact number problems. An enumeration of all regular totally separable sphere packings in $\\mathbb{R}^2$, $\\mathbb{R}^3$, and $\\mathbb{R}^4$ which are based on convex uniform tessellations, honeycombs, and tetracombs, respectively, is presented, as well as a construction of a family of regular totally separable sphere packings in $\\mathbb{R}^d$ that is not based on a convex...

  4. Radiological findings in total colonic aganglionosis

    International Nuclear Information System (INIS)

    The radiological findings pathognomonic of Hirschsprung's disease have been known for quite a long time. However, in addition to those diseases characterized by rectum or rectum-sigmoid aganglionosis (as in the classic form of Hirschsprung's disease), in pediatric pathology of surgical interest severe affections exist characterized by aganglionosis extending from the rectum to the entire colon, and exceptionally as far as the small bowel (ultra-long Hirschsprung's disease). The authors report on the results they obtained in radiological studies of 6 cases of total colonic aganglionosis by means of the current radiological procedures, i.e. plain abdominal films and barium enema. As for total colonic aganglionosis, no diagnostic radiological parameters have been assessed yet. The authors compare their results with those taken from international literature: microcolon with reflux into megaileum (2 out of 6 cases) appears to be the most suggestive X-ray finding for total colonic aganglionosis. Finally, the role is discussed of radiological studies in the diagnostic approach to total colonic aganglionosis. The authors conclude that, even though radiological investigations are indispensable, they are often not conclusive. Therefore, an accurate evaluation of the proximal extension of aganglionosis can be made only at surgery

  5. Signed Total Domination in Graphs

    Institute of Scientific and Technical Information of China (English)

    邢化明; 孙良; 陈学刚

    2003-01-01

    Let G=(V,E) be a simple graph. For any real valued function f:V→R, the weight of f is f(V)=∑f(v) over all vertices v∈V. A signed total dominating function is a function f:V→{-1,1} such that f(N(v))≥1 for every vertex v∈V. The signed total domination number of a graph G equals the minimum weight of a signed total dominating function on G. In this paper, some properties of the signed total domination number of a graph G are discussed.

  6. International energy outlook 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This International Energy Outlook presents historical data from 1970 to 1993 and EIA`s projections of energy consumption and carbon emissions through 2015 for 6 country groups. Prospects for individual fuels are discussed. Summary tables of the IEO96 world energy consumption, oil production, and carbon emissions projections are provided in Appendix A. The reference case projections of total foreign energy consumption and of natural gas, coal, and renewable energy were prepared using EIA`s World Energy Projection System (WEPS) model. Reference case projections of foreign oil production and consumption were prepared using the International Energy Module of the National Energy Modeling System (NEMS). Nuclear consumption projections were derived from the International Nuclear Model, PC Version (PC-INM). Alternatively, nuclear capacity projections were developed using two methods: the lower reference case projections were based on analysts` knowledge of the nuclear programs in different countries; the upper reference case was generated by the World Integrated Nuclear Evaluation System (WINES)--a demand-driven model. In addition, the NEMS Coal Export Submodule (CES) was used to derive flows in international coal trade. As noted above, foreign projections of electricity demand are now projected as part of the WEPS. 64 figs., 62 tabs.

  7. International energy outlook 1996

    International Nuclear Information System (INIS)

    This International Energy Outlook presents historical data from 1970 to 1993 and EIA's projections of energy consumption and carbon emissions through 2015 for 6 country groups. Prospects for individual fuels are discussed. Summary tables of the IEO96 world energy consumption, oil production, and carbon emissions projections are provided in Appendix A. The reference case projections of total foreign energy consumption and of natural gas, coal, and renewable energy were prepared using EIA's World Energy Projection System (WEPS) model. Reference case projections of foreign oil production and consumption were prepared using the International Energy Module of the National Energy Modeling System (NEMS). Nuclear consumption projections were derived from the International Nuclear Model, PC Version (PC-INM). Alternatively, nuclear capacity projections were developed using two methods: the lower reference case projections were based on analysts' knowledge of the nuclear programs in different countries; the upper reference case was generated by the World Integrated Nuclear Evaluation System (WINES)--a demand-driven model. In addition, the NEMS Coal Export Submodule (CES) was used to derive flows in international coal trade. As noted above, foreign projections of electricity demand are now projected as part of the WEPS. 64 figs., 62 tabs

  8. Conceptualizing international education: From international student to international study

    OpenAIRE

    Madge, C.; P Raghuram; Noxolo, P.

    2015-01-01

    In a rapidly changing transnational eduscape, it is timely to consider how best to conceptualize international education. Here we argue for a conceptual relocation from international student to international study as a means to bridge the diverse literatures on international education. International study also enables recognition of the multiple contributions (and resistances) of international students as agents of knowledge formation; it facilitates consideration of the mobility of students ...

  9. FLUORESCENCE CHARACTERIZATION OF IHSS HUMIC SUBSTANCES: TOTAL LUMINESCENCE SPECTRA WITH ABSORBANCE CORRECTION. (R822251)

    Science.gov (United States)

    Total luminescence spectroscopy was applied to the fluorescence characterization of humic substances obtained from the International Humic Substances Society (IHSS). Results show that total luminescence spectra, represented as excitation-emission matrices (EEMs), may be used to d...

  10. Cogema acquires TOTAL's uranium assets

    International Nuclear Information System (INIS)

    On April 28, France's nuclear fuel cycle conglomerate Cogema and petroleum group TOTAL announced a plan in which Cogema will assume ownership of TOTAL's uranium assets worldwide, and as part of the deal, each firm will acquire shares of the other. On June 2, the agreement will be submitted to shareholders and, assuming it is approved, will go into effect this year. The agreement calls for TOTAL to acquire a 10.8-percent share in Cogema, thus becoming its first private sector shareholder, by underwriting a reserve capital increase of FF1.5 billion (approximately US$283 million). In return, Cogema will pay FF2.52 billion for approximately 4.3 percent of TOTAL, as part of a reserve capital increase totalling FF4.07 billion

  11. INTERNAL ENVIRONMENT ANALYSIS TECHNIQUES

    Directory of Open Access Journals (Sweden)

    Caescu Stefan Claudiu

    2011-12-01

    Full Text Available Theme The situation analysis, as a separate component of the strategic planning, involves collecting and analysing relevant types of information on the components of the marketing environment and their evolution on the one hand and also on the organization’s resources and capabilities on the other. Objectives of the Research The main purpose of the study of the analysis techniques of the internal environment is to provide insight on those aspects that are of strategic importance to the organization. Literature Review The marketing environment consists of two distinct components, the internal environment that is made from specific variables within the organization and the external environment that is made from variables external to the organization. Although analysing the external environment is essential for corporate success, it is not enough unless it is backed by a detailed analysis of the internal environment of the organization. The internal environment includes all elements that are endogenous to the organization, which are influenced to a great extent and totally controlled by it. The study of the internal environment must answer all resource related questions, solve all resource management issues and represents the first step in drawing up the marketing strategy. Research Methodology The present paper accomplished a documentary study of the main techniques used for the analysis of the internal environment. Results The special literature emphasizes that the differences in performance from one organization to another is primarily dependant not on the differences between the fields of activity, but especially on the differences between the resources and capabilities and the ways these are capitalized on. The main methods of analysing the internal environment addressed in this paper are: the analysis of the organizational resources, the performance analysis, the value chain analysis and the functional analysis. Implications Basically such

  12. China and IEC international standardization activities

    Institute of Scientific and Technical Information of China (English)

    Su Zhongmin; Guo Chenguang

    2006-01-01

    @@ International Electrotechnical Commission (IEC), one of the currently worlswide largest and most authoritative international standardization organizations,is specialized in developing and promulgating international standards for the electric and electronic fields, which are widespread adopted through out the world and play an important role in the international trade of electric and electronic products. Moreover, according to the 2005 statistics by the World Bank, the population of countries participating in the IEC activities accounts for 92% of the world total and their trade volume accounts for 95% of the global total.

  13. Totality eclipses of the Sun

    CERN Document Server

    Littmann, Mark; Willcox, Ken

    2008-01-01

    A total eclipse of the Sun is the most awesome sight in the heavens. Totality: Eclipses of the Sun takes you to eclipses of the past, present, and future, and lets you see - and feel - why people travel to the ends of the Earth to observe them. - ;A total eclipse of the Sun is the most awesome sight in the heavens. Totality: Eclipses of the Sun takes you to eclipses of the past, present, and future, and lets you see - and feel - why people travel to the ends of the Earth to observe them. Totality: Eclipses of the Sun is the best guide and reference book on solar eclipses ever written. It explains: how to observe them; how to photograph and videotape them; why they occur; their history and mythology; and future eclipses - when and where to see them. Totality also tells the remarkable story of how eclipses shocked scientists, revealed the workings of the Sun, and made Einstein famous. And the book shares the experiences and advice of many veteran eclipse observers. Totality: Eclipses of the Sun is profusely ill...

  14. The first Polish total laryngectomies

    OpenAIRE

    Kierzek, Andrzej; Paprocka-Borowicz, Małgorzata; Pozowski, Andrzej; Kuciel-Lewandowska, Jadwiga

    2013-01-01

    The total removal of the larynx (total laryngectomy), performed in 1872 by the well-known Viennese surgeon Christian A. Theodor Billroth (1829–1894), was an epoch-making event in the history of surgery and laryngology. This paper presents the first surgeons who performed this operation. The first Pole who performed a total laryngectomy (1877) was Julian Kosiński (1833–1914), head of the Surgical Clinic of Imperial University Warsaw. It was the 14th operation of this kind in the world. Several...

  15. Anterior Approach Total Hip Replacement

    Medline Plus

    Full Text Available ... an anterior approach total hip replacement with the patient on a regular OR table supine. My name ... less invasive without being small incision surgery. Obese patients can be easier due to less distribution of ...

  16. Total anomalous pulmonary venous return

    Science.gov (United States)

    TAPVR; Total veins; Congenital heart defect - TAPVR; Cyanotic heart disease - TAPVR ... Fraser CD, Carberry KE. Congenital heart disease. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery . 19th ed. Philadelphia, PA: Elsevier ...

  17. Total Knee Replacement for Women

    Medline Plus

    Full Text Available ... at Florida Orthopedic Institute in Tampa, Florida. Tonight I’ll be moderating a Zimmer Gender Solutions total ... the e-mail seen on your screen, and I’ll do my best to sift through those ...

  18. Total Knee Replacement for Women

    Medline Plus

    Full Text Available ... that we feel because of their health and age has the potential for a total knee to ... I can evaluate? Is there any cut-off age that you would put in regular polyethylene or ...

  19. Minimally Invasive Total Knee Arthroplasty

    Medline Plus

    Full Text Available ... Institute. We're going to be doing an MIS total knee arthroplasty with the Zimmer mobile bearing ... this point. And there is many recipes for MIS knee surgery as there are surgeons. What’s kind ...

  20. Total Product Life Cycle (TPLC)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Total Product Life Cycle (TPLC) database integrates premarket and postmarket data about medical devices. It includes information pulled from CDRH databases...

  1. A Choir for Total Communication.

    Science.gov (United States)

    Knapp, Ruth Ann

    1980-01-01

    The Total Communication Choir of the Saginaw, Michigan, public schools integrates deaf and hearing elementary and junior high students in music performance. All students both sign and sing. Methods used to instruct the choir are described. (SJL)

  2. Qualità totale e mobilità totale

    Directory of Open Access Journals (Sweden)

    Giuseppe Trieste

    2010-04-01

    Full Text Available FIABA ONLUS (Italian Fund for Elimination of Architectural Barriers was founded in 2000 with the aim of promoting a culture of equal opportunities and, above all, it has as its main goal to involve public and private institutions to create a really accessible and usable environment for everyone. Total accessibility, Total usability and Total mobility are key indicators to define quality of life within cities. A supportive environment that is free of architectural, cultural and psychological barriers allows everyone to live with ease and universality. In fact, people who access to goods and services in the urban context can use to their advantage time and space, so they can do their activities and can maintain relationships that are deemed significant for their social life. The main aim of urban accessibility is to raise the comfort of space for citizens, eliminating all barriers that discriminate people, and prevent from an equality of opportunity. “FIABA FUND - City of ... for the removal of architectural barriers” is an idea of FIABA that has already affected many regions of Italy as Lazio, Lombardy, Campania, Abruzzi and Calabria. It is a National project which provides for opening a bank account in the cities of referring, in which for the first time, all together, individuals and private and public institutions can make a donation to fund initiatives for the removal of architectural barriers within its own territory for a real and effective total accessibility. Last February the fund was launched in Rome with the aim of achieving a Capital without barriers and a Town European model of accessibility and usability. Urban mobility is a prerequisite to access to goods and services, and to organize activities related to daily life. FIABA promotes the concept of sustainable mobility for all, supported by the European Commission’s White Paper. We need a cultural change in management and organization of public means, which might focus on

  3. International recommendations

    International Nuclear Information System (INIS)

    Full text: This short presentation will indicate the general radiation protection background to protective measures against foodstuffs contaminated with radioactive substances. A number of international organizations are involved in various aspects of radiation protection, for example, the International Atomic Energy Agency (IAEA), the United Nations Food and Agriculture Organization (FAO), the United Nations Environment Programme (UNEP), and the World Health Organization (WHO). Two international organizations, however, provide the basic background. These are the International Commission on Radiological Protection (ICRP) and the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). UNSCEAR provides the scientific information on radiation levels and effects. It consists of 21 member countries, with truly international coverage. It issues reports to the UN General Assembly, including comprehensive scientific annexes. Its latest comprehensive report was issued in 1982, the next is expected to be published in 1988. That report will include an assessment of the radiological consequences of the Chernobyl accident. The ICRP is a non-governmental organization. It has issued recommendations on radiation protection since 1928. The postulated biological basis for radiation protection recommendations involves two types of biological effects. The so-called non-stochastic effects, mainly due to cell death, appear only when the radiation doses exceed a certain threshold value. These effects, therefore, can only appear after high accidental exposures. After the Chernobyl accident, they only affected about 200 individuals involved in fire extinction and rescue work at the damaged nuclear power plant. Stochastic effects, with some simplification, may be seen as the result of initial changes in the genetic code of some surviving cells. If these cells are germ cells, this may lead to hereditary harm. If they are somatic cells, the result could be cancer

  4. Total Liability for Excessive Harm

    OpenAIRE

    Cooter, Robert D; Porat, Ariel

    2005-01-01

    The harm that each individual causes others is unverifiable in some circumstances where the total harm caused by everyone is verifiable. For example, the environmental agency can often measure the total harm caused by pollution much easier than it can measure the harm caused by each individual polluter. In these circumstances, implementing the usual liability rules or externality taxes is impossible. We propose a novel solution: Hold each participant in the activity responsible for all of the...

  5. Total Liability for Excessive Harm

    OpenAIRE

    Cooter, Robert D; Porat, Ariel

    2004-01-01

    In many circumstances, the total harm caused by everyone is verifiable, and the harm caused by each individual is unverifiable. For example, the environmental agency can measure the total harm caused by pollution much easier than it can measure the harm caused by each individual polluter. In these circumstances, implementing the usual liability rules or externality taxes is impossible. We propose a novel solution: Hold each participant in the activity responsible for all of the excessive harm...

  6. Total synthesis of (-)-spinosyn A.

    Science.gov (United States)

    Mergott, Dustin J; Frank, Scott A; Roush, William R

    2004-08-17

    A convergent, highly stereoselective total synthesis of (-)-spinosyn A (1) is described. Key features of the synthesis include the transannular Diels-Alder reaction of macrocyclic pentaene 11 and the transannular Morita-Baylis-Hillman cyclization of 12 that generates tetracycle 26. The total synthesis of (-)-spinosyn A was completed by a sequence involving the highly beta-selective glycosidation reaction of 13 and glycosyl imidate 30. PMID:15173590

  7. The total charm cross section

    OpenAIRE

    R. Vogt

    2007-01-01

    We assess the theoretical uncertainties on the total charm cross section. We discuss the importance of the quark mass, the scale choice and the parton densities on the estimate of the uncertainty. We conclude that due to the small charm quark mass, which amplifies the effect of the other parameters in the calculation, the uncertainty on the total charm cross section is difficult to quantify.

  8. International relations

    International Nuclear Information System (INIS)

    The French nuclear safety authority (A.S.N.) has participated at different meeting in European Union as nuclear decommissioning assistance programme(N.D.A.P.), Regulatory assistance management group (R.A.M.G.) and Instrument for nuclear safety cooperation (I.N.S.C.). The members of Western European nuclear regulator association (W.E.N.R.A.) met and discussed about the future of W.E.N.R.A. and its representativeness and its cooperation with European nuclear safety regulator group (E.N.S.R.E.G.) and head of European radiation control authorities (H.E.R.C.A.). About International relations it is to noticed a meeting at the invitation of IAEA to discuss about the possibility to resort to the Ines scale for medical events. An audit mission under the IAEA aegis stood at Fessenheim, O.S.A.R.T. for operational safety review team. Two years and a half passed by between the audit mission Integrated regulatory review service (I.R.S.S.) welcome by A.S.N. in november 2006 and the audit mission follow up in 2009, 12 experts from 11 different countries and coordinated by three representatives of IAEA worked, the conclusions were that 90% of recommendations made to A.S.N. in 2006 were treated in a satisfying way; the evaluation gives three new recommendations, 7 new suggestions and 11 new correct practices. A meeting of the commission on safety standards (C.S.S.) stood in april 2009. Some others meeting are to be noticed: nuclear safety and security group (N.S.S.G.), expert group on nuclear and radiation safety (E.G.N.R.S.) instituted by the council of the Baltic sea states (C.B.S.S.) treats data exchange on the national networks of dose rates and surveillance of radioactivity in air. International nuclear regulator association (I.N.R.A.) held its first meeting in april 2009 at Seoul (Korea). Bilateral relations with Poland, Italy, Ukraine and Germany planed cooperation or information exchange in the field of nuclear safety. Participation to conference in Usa, meetings with United

  9. UHMWPE wear particles in different zones around total hip replacements

    Czech Academy of Sciences Publication Activity Database

    Šlouf, Miroslav; Pokorný, D.; Entlicher, G.; Fejfarková, Z.; Synková, Hana; Lapčíková, Monika; Veselý, F.; Sosna, A.

    Madrid: Facultad de Medicina , Universidad Autónoma de Madrid, 2007. s. 27. [UHMWPE International Meeting /3./ "Polyethylene in total joint replacement systems: Concerns and solutions". 14.09.2007-15.09.2007, Madrid] R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : UHMWPE * total joint replacements * polyethylene Subject RIV: CD - Macromolecular Chemistry

  10. Rheology and wear of crosslinked UHMWPE for total joint replacements

    Czech Academy of Sciences Publication Activity Database

    Horák, Zdeněk; Mikešová, Jana; Šlouf, Miroslav; Fencl, J.

    Madrid: Facultad de Medicina , Universidad Autónoma de Madrid, 2007. s. 23. [UHMWPE International Meeting /3./ "Polyethylene in total joint replacement systems: Concerns and solutions". 14.09.2007-15.09.2007, Madrid] R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : UHMWPE * total joint replacements * rheology Subject RIV: CD - Macromolecular Chemistry

  11. Total Quality Management : Aspects of implementation and human resource

    OpenAIRE

    Brynnum, Niels

    2006-01-01

    Problem Discussion Total quality management has become a frequently used term in discussions concerning quality. The international and national competitive environment is in a proces of constant change by the globalisation of markets and increased interdependence of economic agents. This process of change has brought increased demands on the organizations compettiveness and the customers have gained a central role in the organizations focus. Total quality management is considered to be an imp...

  12. Healthcare Professionals’ Perception and Related Factors About Total Quality Management

    OpenAIRE

    Birkan TAPAN; Gayef, Albena; Adem SEZEN; ALICI, Selin; YILDIRIM, Nurdan

    2015-01-01

    Quality defied as extent of features of any product or service to meet expectations of consumers enjoying such product or service. Although it was a concept fist emerged in manufacturing industry, today, it has become an important competitive factor for service institutions as well. Total Quality Management approach is drawing more and more interest as international borders start to fade out in parallel with globalization and increasing competition. Total Quality Management is a management st...

  13. Healthcare Professionals’ Perception and Related Factors About Total Quality Management

    OpenAIRE

    TAPAN, Birkan; Selin ALICI; Gayef, Albena; YILDIRIM, Nurdan; Sezen, Adem

    2015-01-01

    Quality defined as extent of features of any product or service to meet expectations of consumers enjoying such product or service. Although it was a concept first emerged in manufacturing industry, today, it has become an important competitive factor for service institutions as well. Total Quality Management approach is drawing more and more interest as international borders start to fade out in parallel with globalization and increasing competition. Total Quality Management is a ma...

  14. Analysis of internal conversion coefficients

    International Nuclear Information System (INIS)

    An extensive database has been assembled that contains the three most widely used sets of calculated internal conversion coefficients (ICC): [Hager R.S., Seltzer E.C., 1968. Internal conversion tables. K-, L-, M-shell Conversion coefficients for Z=30 to Z=103, Nucl. Data Tables A4, 1-237; Band I.M., Trzhaskovskaya M.B., 1978. Tables of gamma-ray internal conversion coefficients for the K-, L- and M-shells, 10≤Z≤104, Special Report of Leningrad Nuclear Physics Institute; Roesel F., Fries H.M., Alder K., Pauli H.C., 1978. Internal conversion coefficients for all atomic shells, At. Data Nucl. Data Tables 21, 91-289] and also includes new Dirac-Fock calculations [Band I.M. and Trzhaskovskaya M.B., 1993. Internal conversion coefficients for low-energy nuclear transitions, At. Data Nucl. Data Tables 55, 43-61]. This database is linked to a computer program to plot ICCs and their combinations (sums and ratios) as a function of Z and energy, as well as relative deviations of ICC or their combinations for any pair of tabulated data. Examples of these analyses are presented for the K-shell and total ICCs of the gamma-ray standards [Hansen H.H., 1985. Evaluation of K-shell and total internal conversion coefficients for some selected nuclear transitions, Eur. Appl. Res. Rept. Nucl. Sci. Tech. 11.6 (4) 777-816] and for the K-shell and total ICCs of high multipolarity transitions (total, K-, L-, M-shells of E3 and M3 and K-shell of M4). Experimental data sets are also compared with the theoretical values of these specific calculations

  15. Internal audit

    OpenAIRE

    Švandrlíková, Monika

    2011-01-01

    Diplomová práce se zabývá interním auditem procesu nákupu ve společnosti Slovácké strojírny, a.s. Uherský Brod. Cílem je zhodnotit stávající situaci a nabídnout doporučení přinášející přidanou hodnotu organizaci. Analýza současného stavu nákupu byla podkladem pro identifikaci rizik pomocí metody „What can go wrongs“. Na základě těchto poznatků jsou navrženy kontroly a nápravná opatření vedoucí ke snížení rizik. Následná implementace zajistí zlepšení fungování nákupního oddělení a zefektivnění...

  16. Total body water and total body potassium in anorexia nervosa

    International Nuclear Information System (INIS)

    In the ill hospitalized patient with clinically relevant malnutrition, there is a measurable decrease in the ratio of the total body potassium to total body water (TBK/TBW) and a detectable increase in the ratio of total exchangeable sodium to total exchangeable potassium (Nae/Ke). To evaluate body composition analyses in anorexia nervosa patients with chronic uncomplicated semistarvation, TBK and TBW were measured by whole body K40 counting and deuterium oxide dilution in 10 females with stable anorexia nervosa and 10 age-matched female controls. The ratio of TBK/TBW was significantly (p less than 0.05) higher in anorexia nervosa patients than controls. The close inverse correlation found in published studies between TBK/TBW and Nae/Ke together with our results suggest that in anorexia nervosa, Nae/Ke may be low or normal. A decreased TBK/TBW is not a good indicator of malnutrition in the anorexia nervosa patient. The use of a decreased TBK/TBW ratio or an elevated Nae/Ke ratio as a definition of malnutrition may result in inappropriate nutritional management in the patient with severe nonstressed chronic semistarvation

  17. Total body water and total body potassium in anorexia nervosa

    Energy Technology Data Exchange (ETDEWEB)

    Dempsey, D.T.; Crosby, L.O.; Lusk, E.; Oberlander, J.L.; Pertschuk, M.J.; Mullen, J.L.

    1984-08-01

    In the ill hospitalized patient with clinically relevant malnutrition, there is a measurable decrease in the ratio of the total body potassium to total body water (TBK/TBW) and a detectable increase in the ratio of total exchangeable sodium to total exchangeable potassium (Nae/Ke). To evaluate body composition analyses in anorexia nervosa patients with chronic uncomplicated semistarvation, TBK and TBW were measured by whole body K40 counting and deuterium oxide dilution in 10 females with stable anorexia nervosa and 10 age-matched female controls. The ratio of TBK/TBW was significantly (p less than 0.05) higher in anorexia nervosa patients than controls. The close inverse correlation found in published studies between TBK/TBW and Nae/Ke together with our results suggest that in anorexia nervosa, Nae/Ke may be low or normal. A decreased TBK/TBW is not a good indicator of malnutrition in the anorexia nervosa patient. The use of a decreased TBK/TBW ratio or an elevated Nae/Ke ratio as a definition of malnutrition may result in inappropriate nutritional management in the patient with severe nonstressed chronic semistarvation.

  18. Total 2004 annual report; TOTAL 2004 rapport annuel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This annual report of the Group Total brings information and economic data on the following topics, for the year 2004: the corporate governance, the corporate social responsibility, the shareholder notebook, the management report, the activities, the upstream (exploration and production) and downstream (refining and marketing) operating, chemicals and other matters. (A.L.B.)

  19. Elective hemithyroidectomy during total laryngectomy

    Directory of Open Access Journals (Sweden)

    Soheyla Nikakhlagh

    2009-01-01

    Full Text Available Introduction: Routine hemithyroidectomy during total laryngectomy in the setting of advanced stage of laryngeal carcinoma without clear thyroid involvement remains a controversial issue. This study was conducted to assess the rate of thyroid gland involvement in the patients without obvious clinical involvement who were candidates for total laryngectomy. Materials and Methods: In this cross-sectional study, between 1994 and 2007, 186 patients who underwent total laryngectomy with ipsilateral hemithyroidectomy at Imam Khomeini hospital of Ahwaz Jondishapour university, were investigated for thyroid gland involvement. Results: Of 186 patients, 169 cases were men and 17 were women, with mean age of 63 years. Microscopic tissue study revealed tumor invasion to thyroid gland in 7 patients, all of them had clinically advanced disease. Among these patients, 5 cases had transglottic cancer and 2 cases had subglottic cancer. Moreover, 4 patients had thyroid cartilage invasion and in one patient pyriform sinus was involved. Conclusion: There may be no need for thyroidectomy in all total laryngectomy cases. We recommend hemithyroidectomy with isthmectomy during total laryngectomy only in cases with subglottic tumor extension, thyroid cartilage invasion, and pyriform sinus involvement.    

  20. TOTAL THYROIDECTOMY USING CAPSULAR DISSECTION

    Directory of Open Access Journals (Sweden)

    R. Moldovanu

    2008-01-01

    Full Text Available Total thyroidectomy can be performed with low rate of injuries of the recurrent laryngeal nerves and parathyroid glands, with appropriate techniques. The paper describes the technique of total thyroidectomy using capsular dissection and the indications of this operation. There are some steps which should be respected: good exposure of the thyroid gland, careful dissection of the superior pole using the avascular plane between superior pole and cricothyroid muscle, medial retraction of the gland, ligating the tertiary (third order branches of the inferior thyroid artery, near the surface of thyroid parenchyma. Using this type of dissection, the recurrent laryngeal nerves are protected, as well as the blood supply of the parathyroid glands. Conclusions: Total thyroidectomy using capsular dissection is the procedure of choice for multinodular goiter, because avoid the completion thyroidectomy for recurrence or occult thyroid cancer.

  1. International co-operation

    International Nuclear Information System (INIS)

    In 1996, Nuclear Regulatory Authority of the Slovak Republic (NRA SR) ensured the Slovak Republic (SR) obligations with relation to the international agreements and with the SR membership in the IAEA.International co-operation has been ensured on the basis of the bilateral international agreements. With the Ministry of Foreign Affairs co-operation, the SR fulfilled its financial obligations to this organization in due time and in the full scope. Representing Central and Eastern Europe interest in the Board of Governors, the SR participation in the highest executive in the highest executive authority was finished in 1996.The Board of Governors Vice-chairman position was executed by NRA SR Chairman. 5 national and 6 regional technical co-operation and assistance projects were realized in 1996. 12 organizations participated in these projects and accordingly 104 experts took part in training programmes, scientific visits or as the mission members abroad. Besides, Slovak experts participated at work of technical advisory and consultation groups with the significant assistance. In the framework of IAEA co-operation, the SR was visited by 11 expert missions formed by 28 experts from 19 countries including IAEA. Slovak organizations, namely institutes of the Academy of Sciences, Slovak research centres and universities participated in IAEA scientific and research activities through NRA SR. 15 scientific contracts in total were approved and realized and these contracts are utilized as supplementary financing of the own scientific and research projects. Other international co-operation and regional co-operation activities of the NRA SR in 1996 are reviewed

  2. Stereoselective Total Synthesis of Mycalamides

    Institute of Scientific and Technical Information of China (English)

    Masahiro Toyota

    2005-01-01

    @@ 1Introduction Mycalamides A (1a) and B (1b) are potent antiviral compounds from a New Zealand sponge of the genus Mycale. Apart from their antitumor property, mycalamide A (1a) exhibits immunosuppressive action by blocking T-cell activation in mice and is significantly more potent than FK-506 and cyclosporine A. Because of their intriguing biological activity, unique structures and scarce supply of these natural products, mycalamides A (1a) and B (1b) have attracted considerable attention as target molecules for total synthesis, and total, formal, or partial syntheses of this family of compounds have been reported[1,2].

  3. VOICE REHABILITATION FOLLOWING TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Balasubramanian Thiagarajan

    2015-03-01

    Full Text Available Despite continuing advances in surgical management of laryngeal malignancy, total laryngectomy is still the treatment of choice in advanced laryngeal malignancies. Considering the longevity of the patient following total laryngectomy, various measures have been adopted in order to provide voice function to the patient. Significant advancements have taken place in voice rehabilitation of post laryngectomy patients. Advancements in oncological surgical techniques and irradiation techniques have literally cured laryngeal malignancies. Among the various voice rehabilitation techniques available TEP (Tracheo oesophageal puncture is considered to be the gold standard. This article attempts to explore the various voice rehabilitation technique available with primary focus on TEP.

  4. Neck after total laryngectomy: CT study

    Energy Technology Data Exchange (ETDEWEB)

    DiSantis, D.J.; Balfe, D.M.; Hayden, R.E.; Sagel, S.S.; Sessions, D.; Lee, J.K.T.

    1984-12-01

    Computed tomographic scans in 23 patients who had undergone total laryngectomy were analyzed retrospectively to determine normal postoperative appearance and to evaluate the role of CT in assessing recurrent neoplasm. Nine patients without clinical evidence of recurrence illustrated the normal postoperative changes: a round or ovoid neopharynx connecting the base of the tongue with the cervical esophagus and intact fat planes surrounding the neopharynx, neurovascular bundles, and sternocleidomastoid muscles. In the 12 patients with recurrent neoplasm, the CT manifestations included masses involving the internal jugular lymph node chain, tracheostomy site, or paratracheal region. CT supplemented physical examination and indirect mirror examination, providing data regarding presence and extent of recurrent tumor and aiding in planning the mode and scope of therapy.

  5. BUILDING A TOTAL QUALITY CULTURE

    OpenAIRE

    ÖZGENER, Şevki

    2001-01-01

    Continuous cost reduction, productivity and quality improvement have proved essential for organizations tos tay in operation. Managers cannot avoid seeing how quality has developed into the most important competitive weeapon. Many organizations have realized that TQM is the way of managing fort he future TQM is far wider in its application than assuring product or service quality-it i a way of managing business processes to ensure complete customer satisfaction at every stage, internally and ...

  6. Worldwide experience with a totally subcutaneous implantable defibrillator

    DEFF Research Database (Denmark)

    Lambiase, Pier D; Barr, Craig; Theuns, Dominic A M J;

    2014-01-01

    AIMS: The totally subcutaneous implantable-defibrillator (S-ICD) is a new alternative to the conventional transvenous ICD system to minimize intravascular lead complications. There are limited data describing the long-term performance of the S-ICD. This paper presents the first large international...

  7. Anterior Approach Total Hip Replacement

    Medline Plus

    Full Text Available ... and E-poly antioxidant-infused technology during a hip replacement through the anterior supine intramuscular approach. “OR- ... Dr. Keith Berend perform an anterior approach total hip replacement with the patient on a regular OR ...

  8. Total Synthesis of Propolisbenzofuran B†

    OpenAIRE

    Jones, Brian T.; Avetta, Christopher T.; Thomson, Regan J.

    2014-01-01

    The first total synthesis of propolisbenzofuran B, a bioactive natural product isolated from honeybee propolis resin, is reported. The convergent synthesis makes use of a silicon-tether controlled oxidative ketone–ketone cross-coupling and a novel benzofuran-generating cascade reaction to deliver the core structure of the natural product from readily prepared precursors.

  9. Minimally Invasive Total Knee Arthroplasty

    Medline Plus

    Full Text Available ... the NexGen® LPS-Flex Mobile and LPS-Mobile Bearing Knees March 5, 2009 Welcome to this "OR ... MIS total knee arthroplasty with the Zimmer mobile bearing knee. We invite all of you who have ...

  10. Total Knee Replacement for Women

    Medline Plus

    Full Text Available Zimmer Combines Gender Solutions technology May 27, 2009 Good evening. Welcome to “OR-Live” at Tampa General Hospital. My name is Steve Lyons, ... Tonight I’ll be moderating a Zimmer Gender Solutions total knee, performed by my partner, Dr. Ken ...

  11. Total Knee Replacement for Women

    Medline Plus

    Full Text Available Zimmer Combines Gender Solutions technology May 27, 2009 Good evening. Welcome to “OR-Live” at Tampa General Hospital. My name is ... Florida. Tonight I’ll be moderating a Zimmer Gender Solutions total knee, performed by my partner, Dr. ...

  12. Total Knee Replacement for Women

    Medline Plus

    Full Text Available ... Ken, here’s another question. “Do you utilize highly cross linked polyethylene for all your total knees or just in younger patients? I use the highly cross linked polyethylene in all the knees. I think ...

  13. Totally indefinite Euclidean quaternion fields

    OpenAIRE

    Cerri, Jean-Paul; Chaubert, Jérôme; Lezowski, Pierre

    2014-01-01

    We study the Euclidean property for totally indefinite quaternion fields. In particular, we establish the complete list of norm-Euclidean such fields over imaginary quadratic number fields. This enables us to exhibit an example which gives a negative answer to a question asked by Eichler. The proofs are both theoretical and algorithmic.

  14. Minimally Invasive Total Knee Arthroplasty

    Medline Plus

    Full Text Available ... NexGen® LPS-Flex Mobile and LPS-Mobile Bearing Knees March 5, 2009 Welcome to this "OR Live" ... re going to be doing an MIS total knee arthroplasty with the Zimmer mobile bearing knee. We ...

  15. III. Biological effects of radiation from external and internal sources

    Energy Technology Data Exchange (ETDEWEB)

    Stone, R.S.

    1948-05-24

    This report focuses on the hemotological effects of total body irradiation from external and internal sources observed in patients treated for arthritis with radioactive phosphorus administered intravenously.

  16. Edge colouring by total labellings

    DEFF Research Database (Denmark)

    Brandt, Stephan; Rautenbach, D.; Stiebitz, M.;

    2010-01-01

    We introduce the concept of an edge-colouring total k-labelling. This is a labelling of the vertices and the edges of a graph G with labels 1, 2, ..., k such that the weights of the edges define a proper edge colouring of G. Here the weight of an edge is the sum of its label and the labels of its...... two endvertices. We define χ (G) to be the smallest integer k for which G has an edge-colouring total k-labelling. This parameter has natural upper and lower bounds in terms of the maximum degree Δ of G : ⌈ (Δ + 1) / 2 ⌉ ≤ χ (G) ≤ Δ + 1. We improve the upper bound by 1 for every graph and prove χ (G...

  17. CYPRINIDS TOTAL BLOOD PROTEINS DETERMINATION

    Directory of Open Access Journals (Sweden)

    TANŢI PATRICHE

    2013-07-01

    Full Text Available In aquaculture to get a high production is conditioned by awareness and keeping of an unaltered health condition of the biological material. To be aware of the health condition of the biological material in a fish farm allows us to establish the preventive measures required to prevent spreading of a disease and the treatment to be applied in case that a mass disease occurs. The level of the total protein in serum is, first of all, a synthetically indicator of the nutritional condition of the organism, presenting, at the same time, ample qualitative and quantitative variations depending on species, age, sex, stage of sexual maturity, water temperature and especially in correlation with the health condition of fish. Modification in value of the total protein point out some metabolic perturbations in fish body.

  18. Total sternectomy for malignant disease.

    Science.gov (United States)

    París, F; Blasco, E; Tarazona, V; Pastor, J; Zarza, A G; Padilla, J

    1980-09-01

    From 1972 to 1978, six total sternectomies for malignant disease of the sternum were carried out. The clinical data are summarized and the surgical technique is described. After sternectomy, the area of chest wall resection was repaired by suturing a sheet of silicone rubber to the edges of the defect and chest wall stability was assured by using one or two stainless steel struts. Finally the defect was covered with methylmethacrylate prepared and applied inthe operative field. The prosthetic material was shaped until curing by polymerization was complete. We discuss the advantages of this type of reconstruction, the technical details, the use of antibiotics, the surgical drainage, and the need for biopsy prior to carrying out a total sternectomy. PMID:7412352

  19. Outcome after total elbow arthroplasty

    DEFF Research Database (Denmark)

    Plaschke, Hans Christian; Thillemann, Theis M; Brorson, Stig;

    2015-01-01

    BACKGROUND: Total elbow arthroplasties (TEAs) are traditionally grouped into linked and unlinked design. The aim was to analyze the difference in clinical outcomes after TEA based on implant design and indication for surgery and to evaluate primary and revision TEAs. METHODS: A total of 167 TEAs...... (126 primary and 41 revision TEAs) in 141 patients were evaluated with patient-reported outcome measure by the Oxford Elbow Score (OES) and clinically assessed with the Mayo Elbow Performance Score (MEPS), range of motion (ROM), and standard radiographs. RESULTS: The mean follow-up was 10.5 years for...... primary and 7.5 years for revision TEAs. There was no difference in OES or MEPS between linked and unlinked primary TEAs. The OES score in the social-psychological domain was significantly lower in TEAs performed due to fracture (67) compared with rheumatoid arthritis (81; P = .025). ROM in extension...

  20. Total positivity in Markov structures

    OpenAIRE

    Fallat, Shaun; Lauritzen, Steffen; Sadeghi, Kayvan; Uhler, Caroline; Wermuth, Nanny; Zwiernik, Piotr

    2015-01-01

    We discuss properties of distributions that are multivariate totally positive of order two (MTP2) related to conditional independence. In particular, we show that any independence model generated by an MTP2 distribution is a compositional semigraphoid which is upward-stable and singleton-transitive. In addition, we prove that any MTP2 distribution satisfying an appropriate support condition is faithful to its concentration graph. Finally, we analyze factorization properties of MTP2 distributi...

  1. Diastereoselective Total Synthesis of (-)-Galiellalactone.

    Science.gov (United States)

    Kim, Taewoo; Han, Young Taek; An, Hongchan; Kim, Kyeojin; Lee, Jeeyeon; Suh, Young-Ger

    2015-12-18

    An enantioselective total synthesis of (-)-galiellalactone has been accomplished. The key features of the synthesis involve the highly stereoselective construction of the cis-trisubstituted cyclopentane intermediate by a Pd(0)-catalyzed cyclization, the stereospecific introduction of an angular hydroxyl group by Riley oxidation, and the efficient construction of the tricyclic system of (-)-galiellalactone via a combination of diastereoselective Hosomi-Sakurai crotylation and ring-closing metathesis (RCM). PMID:26544529

  2. Total solar eclipse 2001 - Angola

    Czech Academy of Sciences Publication Activity Database

    Marková, E.; Kotrč, Pavel; Křivský, L.; Bělík, M.; Dušek, J.

    Noordwijk : ESA Publication Division, 2002 - (Sawaya-Lacoste, H.), s. 245-248 [Solar Cycle and Space Weather Euroconference /2./. Vico Equense (IT), 24.09.2001-29.09.2001] R&D Projects: GA ČR GA205/01/0420 Institutional research plan: CEZ:AV0Z1003909 Keywords : total solar eclipse * white-light corona Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  3. 78 FR 22530 - Agency Information Collection Activities; Comment Request; Program for International Student...

    Science.gov (United States)

    2013-04-16

    ... Agency Information Collection Activities; Comment Request; Program for International Student Assessment... of Collection: Program for International Student Assessment (PISA 2015) Recruitment and Field Test.... Total Estimated Number of Annual Burden Hours: 6,313. Abstract: The Program for International...

  4. 78 FR 42761 - Agency Information Collection Activities; Comment Request; Program for International Student...

    Science.gov (United States)

    2013-07-17

    ... Agency Information Collection Activities; Comment Request; Program for International Student Assessments... notice will be considered public records. Title of Collection: Program for International Student.... Total Estimated Number of Annual Burden Hours: 2,240. Abstract: PISA (Program for International...

  5. Community College Internal Auditors: Internal Audit Guidebook.

    Science.gov (United States)

    Jones, Ronna; And Others

    This guidebook includes information compiled by the "Audit Manual" committee of Community College Internal Auditors (CCIA) from several California community college districts regarding their internal auditing practices. The first section of the guidebook discusses the purpose of internal audits, indicating that audits assist members of the…

  6. Diverticulosis in total colonic aganglionosis

    International Nuclear Information System (INIS)

    Two infants with total colonic aganglionosis (TCA) extending into the distal part of the ileum are described. Considerable diagnostic delay occurred with the correct diagnosis established first at 3 and 8 months, respectively. Radiologic findings compatible with TCA such as prolonged barium retention, reflux into ileum following barium enema, and foreshortening of colon were not clearly evident initially. Both patients demonstrated multiple acquired colon diverticula which increased both in number and size during the period of observation. These diverticula are probably a late manifestation of the spastic state of the anganglionic colon. Thus demonstration of diverticula supplies a strong evidence of TCA in infants with intestinal obstruction. (orig.)

  7. Total Synthesis of the Ammosamides

    Science.gov (United States)

    Hughes, Chambers C.; Fenical, William

    2010-01-01

    The ammosamides A-C are chlorinated pyrrolo[4,3,2-de]quinoline metabolites isolated from the marine-derived Streptomyces strain CNR-698. The natural products, which possess a dense array of heteroatoms, were synthesized in 17–19 steps from 4-chloroisatin. That the five nitrogen atoms were introduced at the appropriate time and in a suitable oxidation state was key to the success of the total synthesis. Compared to synthetic deschloro ammosamide B, natural ammosamide B is much less susceptible to oxidative degradation. PMID:20131899

  8. Total eclipses of the sun

    CERN Document Server

    Zirker, Jack B

    2014-01-01

    Eclipses have captured attention and sparked curiosity about the cosmos since the first appearance of humankind. Having been blamed for everything from natural disasters to the fall of kings, they are now invaluable tools for understanding many celestial as well as terrestrial phenomena. This clear, easy-to-understand guide explains what causes total eclipses and how they can be used in experiments to examine everything from the dust between the planets to general relativity. A new chapter has been added on the eclipse of July 11, 1991 (the great Hawaiian eclipse). Originally published in 19

  9. Total filmless digital radiology service

    International Nuclear Information System (INIS)

    The completion of a comprehensive picture archiving and communication system (PACS) at Georgetown University Hospital has allowed us to identify a number of technical, administrative, personnel, and operational issues that will affect a total digital radiology service. With a hospital-wide digital imaging network system, computer simulation of communications and storage options, and economic modeling, we have developed a feasibility study and implementation strategy for the smooth transition to a nearly filmless radiology service over the next several years. This paper describes the technical and operational requirements for various database operations, workstations (used in diagnosis, review, and education), and communications. Site and installation planning, personnel training, and transition operations are discussed

  10. First total synthesis of Boehmenan

    Indian Academy of Sciences (India)

    Yamu Xia; Xiaoli Dai; Haixin Liu; Chen Chai

    2014-05-01

    The first total synthesis of dilignan Boehmenan has been achieved. A biomimetic oxidative coupling of the ferulic acid methyl ester in the presence of silver oxide is the crucial step in the synthesis sequence, generating the dihydrobenzofuran skeleton. Hydroxyl group was protected with DHP and reducted with LiAlH4 to afford the intermediate diol. The diol was condensated with the derivative of ferulic acid, then removed the protecting groups, to get Boehmenan. Meanwhile, a study on the ring-opening reaction of the intermediate dihydrobenzofuran neolignan under base conditions was described.

  11. Radiology of total hip replacement

    Energy Technology Data Exchange (ETDEWEB)

    Griffiths, H.J.; Lovelock, J.E.; McCollister Evarts, C.; Geyer, D.

    1984-06-01

    The radiology of total hip replacement (THR) and its complications is reviewed in conjunction with a long-term follow-up study on 402 patients with 501 prostheses. The indications, contraindications, biomechanics, and operative management of these patients is discussed. Clinical complications such as deep vein thrombosis, pulmonary embolism, and hemorrhage are mentioned. Postoperative infections including granulomatous pseudotumors, dislocations and fractures, true loosening of the prosthesis, and heterotopic bone formation (HBF) are discussed and illustrated. The importance of differentiating the lucent line from true loosening is stressed. Mechanical and other clinical complications which are largely ignored by radiologists are also discussed. The uses of arthrography and bone scanning are included.

  12. Solar total energy project Shenandoah

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-10

    This document presents the description of the final design for the Solar Total Energy System (STES) to be installed at the Shenandoah, Georgia, site for utilization by the Bleyle knitwear plant. The system is a fully cascaded total energy system design featuring high temperature paraboloidal dish solar collectors with a 235 concentration ratio, a steam Rankine cycle power conversion system capable of supplying 100 to 400 kW(e) output with an intermediate process steam take-off point, and a back pressure condenser for heating and cooling. The design also includes an integrated control system employing the supervisory control concept to allow maximum experimental flexibility. The system design criteria and requirements are presented including the performance criteria and operating requirements, environmental conditions of operation; interface requirements with the Bleyle plant and the Georgia Power Company lines; maintenance, reliability, and testing requirements; health and safety requirements; and other applicable ordinances and codes. The major subsystems of the STES are described including the Solar Collection Subysystem (SCS), the Power Conversion Subsystem (PCS), the Thermal Utilization Subsystem (TUS), the Control and Instrumentation Subsystem (CAIS), and the Electrical Subsystem (ES). Each of these sections include design criteria and operational requirements specific to the subsystem, including interface requirements with the other subsystems, maintenance and reliability requirements, and testing and acceptance criteria. (WHK)

  13. Employees in Total Quality Management

    Directory of Open Access Journals (Sweden)

    M. G. Matlhape

    2002-12-01

    Full Text Available Companies have become very disillusioned with Total Quality Management (TQM as a solution to their quality related problems. Part of the problem has been that companies' expectations from TQM is as a solution to their existing problems rather than as a new philosophy towards creating value for shareholders, employees, and customers. Employee involvement is usually the element in the TQM philosophy that is most difficult to manage. Central to employee participation within the TQM philosophy is teamwork. In the attempt to facilitate total quality management, this article explores specific South African challenges to achieving this. These areaffirmative action and divers ity management skills shortages, training and development low levels of employee well-being. Working with people requires fundamental understanding of the uniqueness of each individual with their own identity and set of preferences. It also requires an understanding of teams and the mechanisms of making a group of individuals work well or poorly together. This will assist managers to realise active participation, quality output from their workers through individualised, and team based motivational processes.

  14. Qualidade total: Um novo paradigma?

    Directory of Open Access Journals (Sweden)

    Suzana da Rosa Tolfo

    1999-01-01

    Full Text Available Nos últimos anos, o movimento para a implantação da Gestão da Qualidade Total vem crescendo ao redor do mundo. Em razão disso, há uma diversidade de ações realizadas com o nome de "Qualidade Total'. Uma revisão da teoria é complexa, porque existem muitos autores que tratam da questão. Eles escolhem diferentes perspectivas de análises (teóricas e empíricas e há dificuldades em se identificar um corpo conceitual. Há uma ampla difusão de modelos, ferramentas, técnicas, mercado e consultores. Essa popularidade, muitas vezes, faz com que determinadas organizações adotem essa forma de gestão do trabalho sem o conhecimento necessário das implicações que um modelo dessa ordem representa; especialmente no caso brasileiro, suscetível a proposições importadas. O presente artigo propõe um exame daquilo que os fundadores têm articulado sobre TQM, as principais críticas nesta direção e a avaliação de como vem sendo aplicadono nosso país.

  15. Total Value of Phosphorus Recovery.

    Science.gov (United States)

    Mayer, Brooke K; Baker, Lawrence A; Boyer, Treavor H; Drechsel, Pay; Gifford, Mac; Hanjra, Munir A; Parameswaran, Prathap; Stoltzfus, Jared; Westerhoff, Paul; Rittmann, Bruce E

    2016-07-01

    Phosphorus (P) is a critical, geographically concentrated, nonrenewable resource necessary to support global food production. In excess (e.g., due to runoff or wastewater discharges), P is also a primary cause of eutrophication. To reconcile the simultaneous shortage and overabundance of P, lost P flows must be recovered and reused, alongside improvements in P-use efficiency. While this motivation is increasingly being recognized, little P recovery is practiced today, as recovered P generally cannot compete with the relatively low cost of mined P. Therefore, P is often captured to prevent its release into the environment without beneficial recovery and reuse. However, additional incentives for P recovery emerge when accounting for the total value of P recovery. This article provides a comprehensive overview of the range of benefits of recovering P from waste streams, i.e., the total value of recovering P. This approach accounts for P products, as well as other assets that are associated with P and can be recovered in parallel, such as energy, nitrogen, metals and minerals, and water. Additionally, P recovery provides valuable services to society and the environment by protecting and improving environmental quality, enhancing efficiency of waste treatment facilities, and improving food security and social equity. The needs to make P recovery a reality are also discussed, including business models, bottlenecks, and policy and education strategies. PMID:27214029

  16. Bilateral internal laryngoceles mimicking asthma.

    Science.gov (United States)

    Aksoy, Elif A; Elsürer, Cağdaş; Serin, Gediz M; Unal, O Faruk

    2013-05-01

    Laryngocele is an air-filled, abnormal dilation of the laryngeal saccule that extends upward within the false vocal fold, in communication with the laryngeal lumen. A case of 43-year-old male with bilateral internal laryngoceles, who has been treated as asthma for 4 years, is presented. The patient had dyspnea, cough, and excessive phlegm for a month and a late onset stridor. Flexible nasopharyngolaryngoscopy showed bilateral cystic enlargements of the false vocal folds and true vocal folds could not be visualized. Laryngeal CT without contrast enhancement showed bilateral internal laryngoceles. Submucosal total excision of bilateral cystic masses including parts of false vocal folds was performed. The symptoms resolved immediately after surgery. Although the incidence of internal laryngocele is rare, it should be remembered in the differential diagnosis of upper airway problems and diagnostic flexible nasopharnygolaryngoscopy is routinely indicated for airway evaluation in at-risk patients. PMID:24174956

  17. Bilateral internal laryngoceles mimicking asthma

    Directory of Open Access Journals (Sweden)

    Elif A Aksoy

    2013-01-01

    Full Text Available Laryngocele is an air-filled, abnormal dilation of the laryngeal saccule that extends upward within the false vocal fold, in communication with the laryngeal lumen. A case of 43-year-old male with bilateral internal laryngoceles, who has been treated as asthma for 4 years, is presented. The patient had dyspnea, cough, and excessive phlegm for a month and a late onset stridor. Flexible nasopharyngolaryngoscopy showed bilateral cystic enlargements of the false vocal folds and true vocal folds could not be visualized. Laryngeal CT without contrast enhancement showed bilateral internal laryngoceles. Submucosal total excision of bilateral cystic masses including parts of false vocal folds was performed. The symptoms resolved immediately after surgery. Although the incidence of internal laryngocele is rare, it should be remembered in the differential diagnosis of upper airway problems and diagnostic flexible nasopharnygolaryngoscopy is routinely indicated for airway evaluation in at-risk patients.

  18. Internal Control System

    OpenAIRE

    Pavésková, Ivana

    2009-01-01

    This thesis is focused on internal control system. The aim of this thesis is to analyse the development and elements of internal control system, and then demonstrate the possible form of the internal control system in practice. The thesis is divided into two parts -- theoretical and practical. The beginning of the theoretical part is devoted to characteristics of internal controls and their relation to internal control, attention is also paid to economic crimes which the internal control syst...

  19. Application Of Total Quality Management In Library

    OpenAIRE

    Vilas A. Kale

    2013-01-01

    The paper focuses on the application of Total Quality Management in Library in different sub-titles such as Need for Quality Management, Total Quantity Management, Basic components of Total Quality Management, Key Elements in Total Quality Management, Total Quality Management and Libraries, Implementation of Total Quality Management in Library. Application of Total Quality Management in Libraries will provide a vital link for managerial decision makers.

  20. Demand: a total nuclear disarmament

    International Nuclear Information System (INIS)

    This bibliographical note presents a book, in which the authors make a plea for a total nuclear disarmament. They think that humanity cannot be found in competition, but in emulation, and examine how we can get rid of the nuclear bomb. They discuss the background of nuclear energy, state that nuclear weapons have always been useless and extremely dangerous, consider arms race as crazy and as a crime against humanity, recall that nuclear weapons already made numerous victims (Hiroshima, Nagasaki, nuclear tests), that they are a sword of Damocles over 7 billions human beings, that nuclear winter would be an apocalypse, that the Non Proliferation Treaty is a decoy. They discuss the political role of nuclear weapons, and outline that the only solution is their abolition. They discuss what has already been done and what is still to be done, and formulate a strategy for the future

  1. Complications after total hip replacement

    International Nuclear Information System (INIS)

    Complications seen after long-term follow-up examinations of total hip replacement should be treated immediately and completely. In the past decade a considerable increase in revisions has been noted. Radiographic assessment may be regarded as an effective means in diagnosing prosthetic complications from the surgeon's point of view. Examples are given. The difficulties in radiographic assessment of complications after cementless implanation or cemented prostheses without contrast media are mentioned. Prosthesis-related complications, such as mechanical loosening, infection with and without loosening, fatigue fractures and wear, fractures of the femur or pelvis, dislocations and surgical failures, are illustrated, as are clinical courses with gross loss of bone stock after repeated surgery and delayed revisions. Complications not related to the prosthesis such as periarticular ossification, muscle deficiencies, and nervous and vascular lesions are also explained using examples. (orig.)

  2. Sociologist in the total institution

    Directory of Open Access Journals (Sweden)

    Krstić Željko

    2010-01-01

    Full Text Available On the basis of empirical experience from practical work this paper discusses the real place and role of the sociologist in the prison, as a total institution, where sociologists are employed as educators, along with other professions (psychologists, educationalists, social workers, etc., and usually closely cooperating with lawyers. According to the current work regulations, and on the basis of practice so far, the sociologist can work as classical educator, to be in charge of educational groups of inmates, work in the reception department on assessing incoming inmates, and to organize inmates' leisure time by directing them towards pro-social and creative activities (music, painting, reading, etc.. New reform trends in working with inmates suggest new work methods, such as creative workshops, counselling in the sphere of substance abuse and dependency, or expert teams in working with minors. In the prison, the sociologist is indispensable as a researcher of criminal activities.

  3. Total quality management implementation guidelines

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    These Guidelines were designed by the Energy Quality Council to help managers and supervisors in the Department of Energy Complex bring Total Quality Management to their organizations. Because the Department is composed of a rich mixture of diverse organizations, each with its own distinctive culture and quality history, these Guidelines are intended to be adapted by users to meet the particular needs of their organizations. For example, for organizations that are well along on their quality journeys and may already have achieved quality results, these Guidelines will provide a consistent methodology and terminology reference to foster their alignment with the overall Energy quality initiative. For organizations that are just beginning their quality journeys, these Guidelines will serve as a startup manual on quality principles applied in the Energy context.

  4. Total quality management program planning

    Energy Technology Data Exchange (ETDEWEB)

    Thornton, P.T.; Spence, K.

    1994-05-01

    As government funding grows scarce, competition between the national laboratories is increasing dramatically. In this era of tougher competition, there is no for resistance to change. There must instead be a uniform commitment to improving the overall quality of our products (research and technology) and an increased focus on our customers` needs. There has been an ongoing effort to bring the principles of total quality management (TQM) to all Energy Systems employees to help them better prepare for future changes while responding to the pressures on federal budgets. The need exists for instituting a vigorous program of education and training to an understanding of the techniques needed to improve and initiate a change in organizational culture. The TQM facilitator is responsible for educating the work force on the benefits of self-managed work teams, designing a program of instruction for implementation, and thus getting TQM off the ground at the worker and first-line supervisory levels so that the benefits can flow back up. This program plan presents a conceptual model for TQM in the form of a hot air balloon. In this model, there are numerous factors which can individually and collectively impede the progress of TQM within the division and the Laboratory. When these factors are addressed and corrected, the benefits of TQM become more visible. As this occurs, it is hoped that workers and management alike will grasp the ``total quality`` concept as an acceptable agent for change and continual improvement. TQM can then rise to the occasion and take its rightful place as an integral and valid step in the Laboratory`s formula for survival.

  5. Total sleep time severely drops during adolescence.

    Directory of Open Access Journals (Sweden)

    Damien Leger

    Full Text Available UNLABELLED: Restricted sleep duration among young adults and adolescents has been shown to increase the risk of morbidities such as obesity, diabetes or accidents. However there are few epidemiological studies on normal total sleep time (TST in representative groups of teen-agers which allow to get normative data. PURPOSE: To explore perceived total sleep time on schooldays (TSTS and non schooldays (TSTN and the prevalence of sleep initiating insomnia among a nationally representative sample of teenagers. METHODS: Data from 9,251 children aged 11 to 15 years-old, 50.7% of which were boys, as part of the cross-national study 2011 HBSC were analyzed. Self-completion questionnaires were administered in classrooms. An estimate of TSTS and TSTN (week-ends and vacations was calculated based on specifically designed sleep habits report. Sleep deprivation was estimated by a TSTN - TSTS difference >2 hours. Sleep initiating nsomnia was assessed according to International classification of sleep disorders (ICSD 2. Children who reported sleeping 7 hours or less per night were considered as short sleepers. RESULTS: A serious drop of TST was observed between 11 yo and 15 yo, both during the schooldays (9 hours 26 minutes vs. 7 h 55 min.; p<0.001 and at a lesser extent during week-ends (10 h 17 min. vs. 9 h 44 min.; p<0.001. Sleep deprivation concerned 16.0% of chidren aged of 11 yo vs. 40.5% of those of 15 yo (p<0.001. Too short sleep was reported by 2.6% of the 11 yo vs. 24.6% of the 15 yo (p<0.001. CONCLUSION: Despite the obvious need for sleep in adolescence, TST drastically decreases with age among children from 11 to 15 yo which creates significant sleep debt increasing with age.

  6. INTERNATIONAL FRAMEWORK OF INTERNAL AUDIT PROFESSIONAL PRACTICE

    OpenAIRE

    Tomas Hrebik

    2015-01-01

    This article deals with the significance of internal audit and explains that implementation of an internal audit unit into a company organisational structures is going to significantly influence the company business success in the future. Further, it focuses on the strategies, procedures and all organisational processes but also on the methods for reaching the intention on the individual operational levels. Nevertheless the internal audit position depends mainly on the utilisation of the unit...

  7. Penerapan Pengendalian Intern Pada Heifer International Indonesia

    OpenAIRE

    Harianja, Hertauli R

    2010-01-01

    The aim of this research is to find out how Heifer International Indonesia applicate the Internal Control as a International Non Government Organization (INGO) The type of this research is descriptive research using primary data i.e : result of interviews with a related organization staff. Secondary data i.e organization structure, audited financial report, implementing partner list. Data collecting technic is done using interview, observation, documentation techniques. This research is...

  8. Total quality management in blood transfusion.

    Science.gov (United States)

    Smit-Sibinga, C T

    2000-01-01

    Quality management is an ongoing development resulting in consistency products and services and ever increasing customer satisfaction. The ultimum is Total Quality Management. Quality systems and quality management in transfusion medicine have gained considerable attention since the outbreak of the AIDS epidemic. Where product orientation has long been applied through quality control, Good Manufacturing Practice (GMP) principles were introduced, shifting the developments in the direction of process orientation. Globally, and particularly in the more industrialised world people and system orientation has come along with the introduction of the ISO9001 concept. Harmonisation and a degree of uniformity are needed to implement a universally applicable Quality System and related Quality Management. Where the American Association of Blood Banks (AABB) is the professional organisation with the most extensive experience in quality systems in blood transfusion, the European Union and the Council of Europe now are in the process to design a quality system and management applicable to a larger variety of countries, based on a hybrid of current GMP and ISO9001 principles. The International Federation of Red Cross and Red Crescent Societies has developed a more universally to implement Quality Manual, with a pilot project in Honduras. It is recommendable to harmonise the various designs and bring the approaches under one common denominator. PMID:10938970

  9. International migration: a global challenge.

    Science.gov (United States)

    Martin, P; Widgren, J

    1996-04-01

    Trends in international migration are presented in this multiregional analysis. Seven of the world's wealthiest countries have about 33% of the world's migrant population, but under 16% of the total world population. Population growth in these countries is substantially affected by the migrant population. The migration challenge is external and internal. The external challenge is to balance the need for foreign labor and the commitment to human rights for those migrants seeking economic opportunity and political freedom. The internal challenge is to assure the social adjustment of immigrants and their children and to integrate them into society as citizens and future leaders. Why people cross national borders and how migration flows are likely to evolve over the next decades are explained. This report also presents some ways that countries can manage migration or reduce the pressures which force people to migrate. It is recommended that receiving nations control immigration by accelerating global economic growth and reducing wars and human rights violations. This report examines the impact of immigration on international trade, aid, and direct intervention policies. Although migration is one of the most important international economic issues, it is not coordinated by an international group. The European experience indicates that it is not easy to secure international cooperation on issues that affect national sovereignty. It is suggested that countries desiring control of their borders should remember that most people never cross national borders to live or work in another country, that 50% of the world's migrants move among developing countries, and that countries can shift from being emigration to immigration countries. The author suggests that sustained reductions in migration pressure are a better alternative than the "quick fixes" that may invite the very much feared mass and unpredictable movements. PMID:12320315

  10. Hypermnesia and total retrieval time.

    Science.gov (United States)

    Mulligan, Neil W

    2006-05-01

    Recall performance sometimes improves over repeated recall attempts, a phenomenon dubbed hypermnesia. A critical theoretical issue is whether hypermnesia is due to repeated testing per se or increased retrieval time. The present experiments investigated by contrasting five testing conditions. All participants were presented with the same study list followed by either two shorter recall tests or a single longer test. In the multiple test conditions, the tests were either separated by a (filled) 7-minute interval (the multiple-split condition), or presented consecutively, with no break (the multiple-immediate condition). In the single test conditions, the test either began at the start of the recall session, after a (filled) 7-minute delay, or with a 7-minute interruption inserted in the middle. The multiple-split condition produced more reminiscence and hypermnesia than the multiple-immediate condition. More importantly, the multiple-split condition produced greater cumulative recall than any of the other conditions (which did not differ among themselves). That is, single and repeated recall tests of equal total duration are not functionally equivalent. PMID:16766451

  11. The Internal Audit Outsourcing

    OpenAIRE

    Grzegorz Gołębiowski

    2010-01-01

    The article explores an issue of the internal audit outsourcing. It indicates the differences between internal audit, outsourcing and cosourcing of this service as well as their advantages and disadvantages. Drawing from the research on internal audit outsourcing the recent market trends were identified as well as motivations for choosing different forms of internal auditing.

  12. The Internal Audit Outsourcing

    Directory of Open Access Journals (Sweden)

    Grzegorz Gołębiowski

    2010-06-01

    Full Text Available The article explores an issue of the internal audit outsourcing. It indicates the differences between internal audit, outsourcing and cosourcing of this service as well as their advantages and disadvantages. Drawing from the research on internal audit outsourcing the recent market trends were identified as well as motivations for choosing different forms of internal auditing.

  13. Models og International Entrepreneurship

    DEFF Research Database (Denmark)

    Rask, Morten; Servais, Per

    2015-01-01

    International Entrepreneurship, and specifically but not exclusively, International New Ventures (INVs). The three resulting ‘meta-models’ depict the activities and loci of such firms, the motivating factors that give rise to such firms and their growth modalities and strategies. These models reflect the merger...... of entrepreneurship and international business into the field of international entrepreneurship....

  14. Neurology and international organizations

    OpenAIRE

    Mateen, Farrah J.

    2013-01-01

    A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private–public partnerships, commercial interests, armed forces, and universities and c...

  15. Total Petroleum Hydrocarbons (TPH): ToxFAQs

    Science.gov (United States)

    ... a state: This map displays locations where Total Petroleum Hydrocarbons (TPH) is known to be present. On ... I get more information? ToxFAQs TM for Total Petroleum Hydrocarbons (TPH) ( Hidrocarburos Totales de Petróleo (TPH) ) August ...

  16. Total Quality Management as a Paradigm of Business Success

    Directory of Open Access Journals (Sweden)

    Luburić Radoica

    2014-01-01

    Full Text Available Total Quality Management denotes a path by which - both in a stable and a transitional environment, in a professional and scientific way and by applying a variety of methods and techniques, through constant improvements and involvement of all employees - one could get to a model that enables a simultaneous achievement of the top quality level on one hand, and the top management level, on the other. Total Quality Management is a paradigm of business success in the entire world because its set up, inter alia, improves internal functions of an organisation, instils confidence in customers and triggers improvement chain reactions with suppliers and stakeholders. Quality is the foundation and client orientation is the base of the entire concept of total quality management. Placing customers at the centre is the main idea behind the entire quality concept around which everything is built. Improving the capacity of an organization to understand and meet the actual customer needs, both stated and implied, is the main objective of the total quality management. Teamwork and team leadership play a specific role in the total quality management, top managers have the key responsibilities, and activities of the medium and lower level managers together with all employees are of immeasurable significance. Managing the teamwork within the total quality management is not only a requirement for its set up, development and implementation, but also for its survival. Total Quality Management is a managerial philosophy and a mode of running a business in order to achieve success.

  17. Comment on Frank Wilczek's essay "Total Relativity: Mach 2004"

    OpenAIRE

    Hahne, G. E.

    2005-01-01

    Frank Wilczek's essay "Total Relativity: Mach 2004" (PHYSICS TODAY April, 2004, p. 10) cogently updates the status of the intuitively compelling, but partly unrealized, theory of Mach's Principle. I think, however, that an important consequence of the Principle has been skipped: that is, the possibility of linear deformations of the internal structure of elementary particles from the Minkowski structure imposed by the local gravitational (metric) field. [Note: This Comment is similar to one s...

  18. Theorising international environmental law

    OpenAIRE

    Humphreys, Stephen; Otomo, Yoriko

    2014-01-01

    From The Oxford Handbook of International Legal Theory (Florian Hoffmann and Anne Orford, eds, Oxford UP, forthcoming 2014). --- This paper, part of a larger work on international law theory, sketches some early lines of inquiry towards a theoretical understanding of international environmental law. As the body of international law regulating human interaction with the natural world, one might expect this branch of law to be a cornerstone of the international system. Yet in practice,...

  19. Interní audit

    OpenAIRE

    Samuelová, Barbora

    2011-01-01

    The diploma thesis deals with the internal audit, its function and status in a particular organization. The passages look into the development of the profession, relation to the external audit and their comparison, demands on the internal auditor, internal audit structure and the procedure itself. A part of the thesis deals thoroughly with the internal audit in connection with a risk, fraudulent conduct and the importance of the internal control. At the end of the thesis, there are some pract...

  20. Events - France. Stock exchange. International; Actualite - France. Bourse. International

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2000-10-01

    These columns made of short articles report on facts and events in the oil and gas industry in France and worldwide: 1 - France: increase of the production capacity of the ethylene oxide unit of BP's Lavera plant; the 'Plateaux-du-Vexin' gas pipeline crosses the Seine river; completion of the pumping of the front wreckage of the Erika tanker ship; Total inaugurates a vapor recovery unit at the Gonfreville l'Orcher refinery; a national energy saving plan for the abatement of the greenhouse effect; Sercel, a daughter company of Compagnie Generale de Geophysique (CGG), acquires Mark Products division of Shaw industries; the oil prices shoot the international trade; 2 - stock exchange: trend of market values in the context of oil crisis; 3 - international: important oil and gas strike made by TotalFinaElf and OKIOC (Offshore Kazakhstan International Operating Company) in Kazakhstan; communication: a new look for BP; status of Lukoil reserves in Russia; next round for the exploration of the Norwegian North Sea; Transocean Sedco Forex absorbs R and B Falcon Corp and becomes the first drilling contractor; ENI (Italy) becomes operator on the development of South Pars gas field (Iran) for the phases 4 and 5; Shell Overseas Investments BV, BP and Exxon Mobil have signed strategic alliance agreements with China Petroleum and Chemical Corp (Sinopec); first exploration permits for the Faeroe islands; different gas pricing rules for the industrialists in the different European countries. (J.S.)

  1. Magnetic Field - Total Field Intensity for the Epoch 2010.0 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer shows isodynamic lines (lines of equal total intensity of the Earth's magnetic field), derived from the International Geomagnetic Reference Field...

  2. Total abstinence or harm reduction – different strategies of alcohol treatment in research studies and international guidelines [Całkowita abstynencja czy redukcja szkód – różne strategie terapii uzależnienia od alkoholu w świetle badań i międzynarodowych zaleceń

    Directory of Open Access Journals (Sweden)

    Jakubczyk, Andrzej

    2012-06-01

    Full Text Available Alcohol use is considered to be one of the major factors contributing to global health burden as well as social and economic harm. Only about 16% of alcohol dependent individuals enter addiction treatment programs in Poland, with only a few more in Western Europe. The aim of the paper was to present two main treatment strategies of alcohol dependence: total abstinence and harm reduction. The advantages and disadvantages of both treatment goals are presented, pointing to a possibility of treating them as complementary strategies. A need to choose a proper, personalised patient-oriented aim of a treatment program is emphasised, with an option to revise the objective during long-term therapy.. The paper describes implications from investigating the problem of alcohol dependence from a population health perspective. The surprisingly high amount of individuals remitting spontaneously from alcohol dependence without treatment is also discussed, and a possible bias resulting from analysing data on alcoholic subjects coming only from addiction centres, not from general population is taken into consideration. In the second part of the paper, American as well as British alcohol treatment guidelines are presented.

  3. Influence of extraction type on the total phenolics, total flavonoids and total colour change of different varieties of fig extracts

    OpenAIRE

    Jokić, Stela; MUJIĆ, Ibrahim; Bucić-Kojić, Ana; Velić, Darko; Bilić, Mate; Planinić, Mirela; Lukinac, Jasmina

    2014-01-01

    The study examined the influence of ultrasound-assisted extraction and solid-liquid extraction with 80% of aqueous ethanol solution on the total phenolics, total flavonoids and total colour change of extracts from five different varieties of figs (Bjelica, Termenjača, Crnica, Bružetka bijela and Šaraguja). The total phenolic content was determined by using Folin Ciocalteau assay. The content of total flavonoids was measured spectrophotometrically by using the aluminium chloride colourimetric ...

  4. Cataractogenesis after total body irradiation

    International Nuclear Information System (INIS)

    Purpose: To evaluate the prognostic factors and the ophthalmologic follow-up on cataract formation following total body irradiation (TBI) prior to bone marrow transplantation (BMT). Methods and Materials: Between 1980 and 1992, 494 patients were referred to our department for TBI prior to BMT. The mean age was 32 ± 11 (median: 32, range: 2-63) years and the male to female ratio was 1.6 (304:190). The majority of patients were treated for acute leukemia (lymphoblastic, n = 177, 36%; or nonlymphoblastic, n = 139, 28%); 80 (16%) for chronic myeloid leukemia, 60 (12%) for non-Hodgkin's lymphoma, 23 (5%) for multiple myeloma, and 15 (3%) for other malignancies. Two hundred and fifty-four (51%) patients were grafted in the first complete remission (CR), 118 (24%) in second CR. Allogeneic BMT was performed in 210 (43%) patients, and autologous BMT in 284 (57%). Methotrexate combined to steroids (n = 47, 22%) or to cyclosporine (n = 163, 78%) was administered for graft-versus-host disease (GvHD) prophylaxis. In 188 patients (38%), heparin was used in the prevention of veno-occlusive disease (VOD) of the liver. Furthermore, steroid administration was registered in 223 patients (45%). The conditioning chemotherapy consisted of cyclophosphamide (Cy) alone in 332 (67%) patients. Total-body irradiation was administered either in single dose (STBI; 10 Gy in 1 day, n = 291) or in six fractions (FTBI; 12 Gy over 3 consecutive days, n = 203) before BMT. The mean instantaneous dose rate was 0.0574 ± 0.0289 Gy/min (0.024-0.1783). It was < 0.048 Gy/min in 157 patients (LOW group), ≥ 0.048 Gy/min and < 0.09 Gy/min in 301 patients (MEDIUM group), and ≥ 0.09 Gy/min in 36 patients (HIGH group). Results: When considering all patients, 42 (8.5%) patients developed cataracts after 13 to 72 months (median: 42 months) with a 5-year estimated cataract incidence (ECI) of 23%. Thirty-three (11.3%) out of 291 patients in the STBI group, and 9 (4.4%) out of 203 patients in the FTBI group

  5. CONCEPT OF OPERATIONS PLANS for Phase I the INTERNATIONAL PILOT FOR Global Radiological source SORTING, Tracking, AND MONITORING (GradSStraM) Using eMERGING RFID AND WEB 2.0 TECHNOLOGIES TO PROVIDE TOTAL ASSET AND INFORMATION VISUALIZATIONA United States-European Union Lighthouse Priority Project for fostering trade and reducing regulatory burden

    International Nuclear Information System (INIS)

    Thousands of shipments of radioisotopes developed in the United States (US) are transported domestically and internationally for medical and industrial applications, including to partner laboratories in European Union (EU) countries. Over the past five years, the Environmental Protection Agency (EPA), the Department of Energy (DOE), and Oak Ridge National Laboratory (ORNL) have worked with state regulatory compliance personnel, key private sector shippers and carriers, the Department of Homeland Security (DHS), the Department of Transportation (DOT), the Department of Defense (DoD) and the Nuclear Regulatory Commission (NRC) on Radio Frequency Identification (RFID) tracking and monitoring of medical and industrial radioisotopes in commerce. The EPA Radiological Source Tracking and Monitoring (RadSTraM) project tested, evaluated, and integrated RFID technologies in laboratory settings, and at multiple private-sector shipping and distribution facilities (Perkin Elmer and DHL) using common radioisotopes used in everyday commerce. The RFID tracking was also tested in association with other deployed technologies including radiation detection, chemical/explosives detection, advanced imaging, lasers, and infrared scanning. At the 2007 EU-US Summit, the leaders of the US Department of Commerce (DOC) and EU European Commission (EC) committed to pursue jointly directed Lighthouse Priority Projects. These projects are intended to 'foster cooperation' and 'reduce regulatory burdens' with respect to transatlantic commerce. The Transatlantic Economic Council (TEC) Lighthouse Project on Radio Frequency Identification (RFID) has been directed to 'develop a joint framework for cooperation on identification and development of best practices for Radio Frequency Identification (RFID) technologies.' The RFID Lighthouse Priority Project commits both sides to endeavor to align U.S. and EU regulatory and policy approaches on RFID technologies, including pilot projects in the public sector

  6. CONCEPT OF OPERATIONS PLANS for Phase I the INTERNATIONAL PILOT FOR Global Radiological source SORTING, Tracking, AND MONITORING (GradSStraM) Using eMERGING RFID AND WEB 2.0 TECHNOLOGIES TO PROVIDE TOTAL ASSET AND INFORMATION VISUALIZATIONA United states- European Union Lighthouse Priority Project for fostering trade and reducing regulatory burden

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Randy M [ORNL

    2009-01-01

    Thousands of shipments of radioisotopes developed in the United States (US) are transported domestically and internationally for medical and industrial applications, including to partner laboratories in European Union (EU) countries. Over the past five years, the Environmental Protection Agency (EPA), the Department of Energy (DOE), and Oak Ridge National Laboratory (ORNL) have worked with state regulatory compliance personnel, key private sector shippers and carriers, the Department of Homeland Security (DHS), the Department of Transportation (DOT), the Department of Defense (DoD) and the Nuclear Regulatory Commission (NRC) on Radio Frequency Identification (RFID) tracking and monitoring of medical and industrial radioisotopes in commerce. The EPA Radiological Source Tracking and Monitoring (RadSTraM) project tested, evaluated, and integrated RFID technologies in laboratory settings, and at multiple private-sector shipping and distribution facilities (Perkin Elmer and DHL) using common radioisotopes used in everyday commerce. The RFID tracking was also tested in association with other deployed technologies including radiation detection, chemical/explosives detection, advanced imaging, lasers, and infrared scanning. At the 2007 EU-US Summit, the leaders of the US Department of Commerce (DOC) and EU European Commission (EC) committed to pursue jointly directed Lighthouse Priority Projects. These projects are intended to 'foster cooperation' and 'reduce regulatory burdens' with respect to transatlantic commerce. The Transatlantic Economic Council (TEC) Lighthouse Project on Radio Frequency Identification (RFID) has been directed to 'develop a joint framework for cooperation on identification and development of best practices for Radio Frequency Identification (RFID) technologies.' The RFID Lighthouse Priority Project commits both sides to endeavor to align U.S. and EU regulatory and policy approaches on RFID technologies, including pilot

  7. Models of international entrepreneurship

    DEFF Research Database (Denmark)

    Rask, Morten; Servais, Per

    2012-01-01

    ). These models reflect the merger of entrepreneurship and international business into the field of international entrepreneurship. Managers in international entrepreneurial firms and students in international business and entrepreneurship can use the models as framework for understanding international......The purpose with this article is to review models used to describe and explain the establishment and development of international new ventures in order to investigate how and why international new ventures are established and developed. This article attempts an integration of extant theory on...... International Entrepreneurship, and specifically but not exclusively, International New Ventures (INVs). The three resulting ‘meta-models’ depict the activities and loci of such firms (Figure 1), the motivating factors that give rise to such firms (Figure 2) and their growth modalities and strategies (Figure 3...

  8. Internal migration and income of immigrant families

    OpenAIRE

    Rashid, Saman

    2004-01-01

    Using a longitudinal dataset from the years 1995 and 2000, respectively, this study examines whether migration within the host country of Sweden generates higher total annual income for (two-earner) immigrant families. The empirical findings indicate that internal migration generates a positive outcome in terms of higher family income for newly arrived refugee-immigrant families. Further, with the length of residence in the host country, the monetary gain accruing from internal migration decr...

  9. The Risk-Return Attributes of International Real Estate Equities

    OpenAIRE

    Paul K. Asabere; Robert Kleiman; Carl McGowan

    1991-01-01

    This paper examines the risk and return attributes of international real estate equities over the 1980-1988 time period. The empirical results indicate that international real estate equities offer higher returns as well as greater total and systematic risk than U.S.-based REITs. The results also indicate that international real estate equities are weakly positively correlated with the return on REITs. International real estate equities achieve higher values for both the Treynor and Jensen me...

  10. Effective Form of Reproducing the Total Financial Potential of Ukraine

    Directory of Open Access Journals (Sweden)

    Portna Oksana V.

    2015-03-01

    Full Text Available Development of scientific principles of reproducing the total financial potential of the country and its effective form is an urgent problem both in theoretical and practical aspects of the study, the solution of which is intended to ensure the active mobilization and effective use of the total financial potential of Ukraine, and as a result — its expanded reproduction as well, which would contribute to realization of the internal capacities for stabilization of the national economy. The purpose of the article is disclosing the essence of the effective form of reproducing the total financial potential of the country, analyzing the results of reproducing the total financial potential of Ukraine. It has been proved that the basis for the effective form of reproducing the total financial potential of the country is the volume and flow of resources, which are associated with the «real» economy, affect the dynamics of GDP and define it, i.e. resource and process forms of reproducing the total financial potential of Ukraine (which precede the effective one. The analysis of reproducing the total financial potential of Ukraine has shown that in the analyzed period there was an increase in the financial possibilities of the country, but steady dynamics of reduction of the total financial potential was observed. If we consider the amount of resources involved in production, creating a net value added and GDP, it occurs on a restricted basis. Growth of the total financial potential of Ukraine is connected only with extensive quantitative factors rather than intensive qualitative changes.

  11. Cutaneous manifestations of internal malignancy

    Directory of Open Access Journals (Sweden)

    A Ayyamperumal

    2012-01-01

    Full Text Available Background: Many malignancies affecting the internal organs display cutaneous manifestations which may be either specific (tumor metastases or nonspecific lesions. Aims: The study is aimed at determining the frequency and significance of cutaneous manifestations among patients with internal malignancy. Materials and Methods: 750 cases of proven internal malignancy, who attended a cancer chemotherapy center in South India, were studied. Specific infiltrates were confirmed by histopathology, fine needle aspiration cytology (FNAC and marker studies. Results: Out of the 750 patients with internal malignancy, skin changes were seen in a total of 52 (6.93% patients. Conclusion: Cutaneous metastases (specific lesions were seen in 20 patients (2.66%: contiguous in 6 (0.8%, and non-contiguous in 14 (1.86%. Nonspecific skin changes were seen in 32 patients (4.26%. None of our patients presented with more than one type of skin lesions. Herpes zoster was the most common nonspecific lesion noticed in our patients, followed by generalized pruritus, multiple eruptive seborrheic keratoses, bullous disorder, erythroderma, flushing, purpura, pyoderma gangrenosum, insect bite allergy and lichenoid dermatitis.

  12. Nordic Seas total alkalinity data in CARINA

    Directory of Open Access Journals (Sweden)

    A. Olsen

    2009-08-01

    Full Text Available Water column data of carbon and carbon relevant hydrographic and hydrochemical parameters from 188 previously non-publicly available cruises in the Arctic, Atlantic, and Southern Ocean have been retrieved and merged into a new database: CARINA (CARbon IN the Atlantic. The data have been subject to rigorous quality control (QC in order to ensure highest possible quality and consistency. The data for most of the parameters included were examined in order to quantify systematic biases in the reported values, i.e. secondary quality control. Significant biases have been corrected for in the data products, i.e. the three merged files with measured, calculated and interpolated values for each of the three CARINA regions; the Arctic Mediterranean Seas (AMS, the Atlantic (ATL and the Southern Ocean (SO. With the adjustments the CARINA database is consistent both internally as well as with GLODAP (Key et al., 2004 and is suitable for accurate assessments of, for example, oceanic carbon inventories and uptake rates and for model validation. The Arctic Mediterranean Seas includes the Arctic Ocean and the Nordic Seas, and the quality control was carried out separately in these two areas. This contribution presents an account of the quality control of the total alkalinity (ALK data from the Nordic Seas in CARINA. Out of the 35 cruises from the Nordic Seas included in CARINA, 21 had ALK data. The data from 6 of these were found to be of low quality and should not be used. Of the others, 3 were found to be biased low and were subject to adjustment. Thus the final CARINA data product contains ALK data from 15 cruises from the Nordic Seas, and these data appear consistent to ±3 μmol kg−1.

  13. Fifth International Conference KSE 2013

    CERN Document Server

    Denoeux, Thierry; Tran, Dang; Le, Anh; Pham, Son; Knowledge and Systems Engineering

    2014-01-01

    The field of Knowledge and Systems Engineering (KSE) has experienced rapid development and inspired many applications in the world of information technology during the last decade. The KSE conference aims at providing an open international forum for presentation, discussion and exchange of the latest advances and challenges in research of the field. These proceedings contain papers presented at the Fifth International Conference on Knowledge and Systems Engineering (KSE 2013), which was held in Hanoi, Vietnam, during 17–19 October, 2013. Besides the main track of contributed papers, which are compiled into the first volume, the conference also featured several special sessions focusing on specific topics of interest as well as included one workshop, of which the papers form the second volume of these proceedings. The book gathers a total of 68 papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intell...

  14. International Transplant Nurses Society

    Science.gov (United States)

    ... 25th Annual ITNS Symposium The International Transplant Nurses Society (ITNS) cordially invites transplant nurses and other transplant ... pocket guide, developed by the International Transplant Nurses Society (ITNS), provides an overview of the interventions used ...

  15. Hepatitis Foundation International

    Science.gov (United States)

    ... partner – it's your best friend. Welcome. The Hepatitis Foundation International (HFI) is a 501 (c) 3 non- ... and cures is your participation in the Hepatitis Foundation International Registry. Whether you are affected, a caregiver, ...

  16. International diversification and Microfinance

    NARCIS (Netherlands)

    Galema, Rients; Lensink, Robert; Spierdijk, Laura

    2011-01-01

    International commercial banks, institutional investors, and private investors have become increasingly interested in financing microfinance institutions (MFIs). This paper investigates whether adding microfinance funds to a portfolio of risky international assets yields diversification gains. By us

  17. Generalized internal multiple imaging

    KAUST Repository

    Zuberi, Mohammad Akbar Hosain

    2014-12-04

    Various examples are provided for generalized internal multiple imaging (GIMI). In one example, among others, a method includes generating a higher order internal multiple image using a background Green\\'s function and rendering the higher order internal multiple image for presentation. In another example, a system includes a computing device and a generalized internal multiple imaging (GIMI) application executable in the computing device. The GIMI application includes logic that generates a higher order internal multiple image using a background Green\\'s function and logic that renders the higher order internal multiple image for display on a display device. In another example, a non-transitory computer readable medium has a program executable by processing circuitry that generates a higher order internal multiple image using a background Green\\'s function and renders the higher order internal multiple image for display on a display device.

  18. International OCD Foundation

    Science.gov (United States)

    ... and productive lives. Join Donate Volunteer Events International OCD Foundation Our mission is to help all individuals ... to the IOCDF. Learn More Order a Bouquet OCD Awareness Week #OCDweek International OCD Awareness Week is ...

  19. International trade in uranium

    International Nuclear Information System (INIS)

    The subject is discussed under the following headings: need for security of uranium supply; pressures on international trade; mechanism of international trade; non-proliferation and uranium trade; means of increasing security of supply. (U.K.)

  20. International Map Year 2015

    OpenAIRE

    Miljenko Lapaine; Dražen Tutić

    2012-01-01

    The International Cartographic Association (ICA) decided to establish the International Map Year (IMY) during the year 2015. The working group was formed and terms of reference accepted by the ICA Executive Committee.

  1. Developments in international bioenergy trade

    International Nuclear Information System (INIS)

    The aim of this paper is to present a synthesis of the main developments and drivers of international bioenergy trade in IEA Bioenergy Task 40 member countries, based on various country reports written by Task 40 members. Special attention is given to pellet and ethanol trade. In many European countries such as Belgium, Finland, the Netherlands, Sweden and the UK, imported biomass contributes already significantly (between 21% and 43%) to total biomass use. Wood pellets are currently exported by Canada, Finland and (to a small extent) Brazil and Norway, and imported by Sweden, Belgium, the Netherlands, and the UK. In the Netherlands and Belgium, pellet imports nowadays contribute to a major share to total renewable electricity production. Trade in bio-ethanol is another example of a rapidly growing international market. With the EU-wide target of 5.75% biofuels for transportation in 2010 (and 10% in 2020), exports from Brazil and other countries to Europe are likely to rise as well. Major drivers for international bioenergy trade in general are the large resource potentials and relatively low production costs in producing countries such as Canada and Brazil, and high fossil fuel prices and various policy incentives to stimulate biomass use in importing countries. However, the logistic infrastructure both in exporting and importing countries needs to be developed to access larger physical biomass volumes and to reach other (i.e. smaller) end-consumers. It is concluded that international bioenergy trade is growing rapidly, far beyond what was deemed possible only a few years ago, and may in the future in some Task 40 countries surpass domestic biomass use, especially for specific applications (e.g. transport fuels). (author)

  2. conflicts in international teams

    OpenAIRE

    Kurdovanidze, Salome

    2014-01-01

    This thesis aims to define international team and conflicts and identify the essential competencies for a manager and employee of international teams. It is argued that everyone in an international team should possess more skills and competencies than those who belong to homogeneous teams. As a result, representatives of international team must be able to understand culturally diverse backgrounds manage conflicts constructively, and comprehend different strategies to handle sensitive cases. T...

  3. Essays on international economics

    OpenAIRE

    Özer, Seda Köymen

    2015-01-01

    In these essays, I examine quantitatively some of the classic questions in the field of International Economics: What is the impact of international trade on consumption and productivity? How does international trade affect income inequality? How do exchange rates movements affect real output and productivity? This dissertation is composed of three chapters, each covering one of these topics.The first chapter, based on my paper "Measured Gains from International Trade" with Ariel Burstein, r...

  4. External and internal audit

    OpenAIRE

    Froňková, Hana

    2011-01-01

    Dissertation includes problems of internal and external audit. The goal of this work is on the basis teoretical knowledge and information got from experience, to do internal and external audit of fulfilment by drawings of financial subvence. The result of both made audits is final report.Work is composed from three parts, first part- theoretical-describes progress of internal audit, its essence and definitions, regulation frame, which characteristics ought to fulfil an internal auditor, then ...

  5. International telecommunications market regulation

    OpenAIRE

    Productivity Commission

    2001-01-01

    On 23 February 1999 the Assistant Treasurer referred international telecommunic-ations market regulation for inquiry and report within six months. The report focused on the reform of international telecommunications markets, in particular on the payment arrangements between providers of international telecommunications services.

  6. Petroleum and international policy

    International Nuclear Information System (INIS)

    To illustrate the relation between the petroleum and the international policy, the author presents the place of the petroleum industry in the international relations by an analysis of the historical aspects, the states and international organizations interventions and the prices evolution. (A.L.B.)

  7. International Week '13

    OpenAIRE

    Kirchhübel, Nicola; Fattoul, Soufian

    2012-01-01

    This project deals with planning the event International Week 2013 - to raise awareness about the international standing of RUC and what it has to offer both international and Danish students. The project features a discussion of potential collaborative partners that could be involved, the marketing strategies that could be used, and the mechanics of achieving the end goal.

  8. Windows® Internals

    CERN Document Server

    Russinovich, Mark E; Ionescu, Alex

    2009-01-01

    See how the core components of the Windows operating system work behind the scenes-guided by a team of internationally renowned internals experts. Fully updated for Windows Server 2008 and Windows Vista, this classic guide delivers key architectural insights on system design, debugging, performance, and support-along with hands-on experiments to experience Windows internal behavior firsthand.Delve inside Windows architecture and internals:Understand how the core system and management mechanisms work-from the object manager to services to the registryExplore internal system data structures usin

  9. Determination of thorium and uranium in total diet samples by inductively coupled plasma mass spectrometry

    International Nuclear Information System (INIS)

    The Th and U contents in total diet samples were determined by inductively coupled plasma mass spectrometry (ICP-MS). The internal standardization method was adopted to compensate for non-spectral interferences arising from matrix elements in the sample solutions. Concentration levels of the order of pg ml-1 of Th and U in the total diet sample were determined easily and rapidly by using Bi as an internal standard. The mean concentrations and standard deviations of Th and U in the total diet samples were found to be 25 ± 12 and 44 ± 20 ng g-1 of ash, respectively (for n = 62). (author)

  10. A Hierarchy of Totally Ordered Multicasts

    OpenAIRE

    Wilhelm, U. G.; Schiper, A

    1995-01-01

    The increased interest in protocols that provide a total order on message delivery has led to several different definitions of total order. In this paper we investigate these different definitions and propose a hierarchy that helps to better understand the implications of the different possibilities in terms of guarantees and communication cost. We identify two definitions: {\\em weak total order} and {\\em strong total order}, which are at the extremes of the proposed hierarchy, and incorpor...

  11. International atomic laboratory

    International Nuclear Information System (INIS)

    Some thirty kilometers to the south-east of Vienna, in the village of Seibersdorf, the International Atomic Energy Agency will have its functional laboratory, the first atomic laboratory to be built by peaceful world-wide co-operation. The building is expected to be completed around the middle of 1960 and the scientific installations will start immediately thereafter. The staff (14 Professional and 24 of the General Service category) for the laboratory are also expected to be engaged at that time and it should be possible to start operating the laboratory in the last quarter of 1960. It is estimated that the construction work will cost about US $400 000 and the total equipment will be worth between $200 000 and $300 000. The United States Government is donating $600 000 for this purpose. The operating costs during 1961, the first full year of operation, will be a little over $240 000. The scope of the laboratory should be limited to certain broad functions. The maximum functions envisaged were: (a) standardization of isotopes and preparation of radioactive standards; (b) calibration and adaptation of measuring equipment; (c) quality control of special materials for nuclear technology; (d) measurements and analysis in connexion with the Agency's safeguards and health and safety programme; and (e) services for Member States which can be undertaken with the facilities needed for the former activities. The idea behind this recommendation will be clear if it is remembered that the research functions of the Agency are governed mostly by its other activities, by its Statutory obligation to encourage and assist peaceful atomic energy work in Member States and establish standards for health and safety and for safeguards against military use

  12. International health care spending.

    Science.gov (United States)

    Schieber, G J; Puollier, J P

    1986-01-01

    Trends in health are reviewed for the member countries of the Organization for Economic Cooperation and Development (OECD) covering the following: the basic difficulties inherent in international comparative studies; the absolute levels of health expenditures in 1984; the levels and rates of growth of the health share in the gross domestic product (GDP) and the public share of total health expenditures; the elasticities of real health expenditures to real GDP for the 1960-75, 1975-84, and 1960-84 time periods; growth in health expenditures for the largest 7 OECD countries in terms of growth in population, health prices, health care prices in excess of overall prices, and utilization/intensity of services per person. International comparisons are a problem due to differences in defining the boundaries of the health sector, the heterogeneity of data, and methodological problems arising from comparing different economic, demographic, cultural, and institutional structures. The most difficult problem in international comparisons of health expenditures is lack of appropriate measures of health outcome. Exhibit 1 contains per capita health expenditures denominated in US dollars based on GDP purchasing power parities for 21 OECD countries for 1984. Per capita health expenditures ranged from less than $500 in Greece, Portugal, and Spain to over $1400 in Sweden and the US, with an OECD average of $871. After adjusting for price level differences, there still appears to be a greater than 3-fold difference in the "volume" of services consumed across the OECD countries. To determine if per capita health expenditures are related to a country's wealth as measured by its per capita GDP, the relationship between per capita health expenditures and per capita GDP for the 21 countries were examined for 1984. The data points and the "best fitting" trend line indicate a statistically significant relationship in which each $100 difference in per capita GDP is associated with a $10

  13. 12 CFR 613.3200 - International lending.

    Science.gov (United States)

    2010-01-01

    ... transaction with a voting stockholder of the bank for the substantial benefit of the shareholder; and (3) Any... eligible cooperatives hold in such entity multiplied by the value of the total assets of such entity; and... 12 Banks and Banking 6 2010-01-01 2010-01-01 false International lending. 613.3200 Section...

  14. TECAB - Totally Endoscopic Coronary Artery Bypass

    Medline Plus

    Full Text Available ... And the bypass vessel is the so-called “internal mammary artery.” That’s an artery, as opposed to ... you very much. -- while I’m preparing the internal mammary artery for bypass. Good. All right. We ...

  15. TECAB - Totally Endoscopic Coronary Artery Bypass

    Medline Plus

    Full Text Available ... and we also like that aspect of this new type of surgery. The internal mammary artery is ... when it’s needed. Internal mammary artery. That’s a new word. That’s a new word, huh? Naked or ...

  16. TOTAL GLOBAL DOMINATION IN FUZZY GRAPH

    OpenAIRE

    Rohini, R.; P.Gladyis; C. V. R. Harinarayanan

    2014-01-01

    Let G be a fuzzy graph without isolated nodes. A subset D of V is said to be a total dominating set if every node in V is dominated by a node in D. A total dominating set D of a graph G= (V,E ) is a total global fuzzy dominating set (t.g.f.d. set) if D is also a total dominating set of G . The total global fuzzy domination number γtgf(G) of G is the minimum cardinality of a t.g.f.d. set for some classes of fuzzy graphs and obtain bounds for the same.

  17. Computer-Navigated Total Knee Arthroplasty Utilization.

    Science.gov (United States)

    Bala, Abiram; Penrose, Colin Thomas; Seyler, Thorsten Markus; Mather, Richard Chad; Wellman, Samuel Secord; Bolognesi, Michael Paul

    2016-07-01

    Computer-navigated total knee arthroplasty (CN-TKA) has been used to improve component alignment, though the evidence is currently mixed on whether there are clinically significant differences in long-term outcomes. Given the established increased costs and operative time, we hypothesized that the utilization rate of CN-TKA would be decreasing relative to standard TKA in the Medicare population given the current health care economic environment. We queried 1,914,514 primary TKAs performed in the entire Medicare database from 2005 to 2012. Current Procedural Terminology (CPT) and International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes were used to identify and separate CN-TKAs. Utilization of TKA was compared by year, gender, and region. Average change in cases per year and compound annual growth rate (CAGR) were used to evaluate trends in utilization of the procedure. We identified 30,773 CN-TKAs performed over this time period. There was an increase in utilization of CN-TKA per year from 984 to 5,352 (average = 572/year, R (2) = 0.85, CAGR = 23.58%) from 2005 to 2012. In contrast, there was a slight decrease in overall TKA utilization from 264,345 to 230,654 (average = 4297/year, R (2) = 0.74, CAGR = - 1.69%). When comparing proportion of CN-TKA to all TKAs, there was an increase from 0.37 to 2.32% (average 0.26%/year, R (2) = 0.88, CAGR = 25.70%). CN-TKA growth in males and females was comparable at 24.42 and 23.11%, respectively. The South region had the highest growth rate at 28.76%, whereas the Midwest had the lowest growth rate at 15.51%. The Midwest was the only region that peaked (2008) with a slow decline in utilization until 2012. Despite increased costs with unclear clinical benefit, CN-TKA is increasing in utilization among Medicare patients. Reasons could include patient preference, advertising, proper of coding the procedure, and increased publicly available information about

  18. Determination of the total inductance of TPF-I

    Science.gov (United States)

    Kunamaspakorn, T.; Poolyarat, N.; Picha, R.; Promping, J.; Onjun, T.

    2015-05-01

    Thailand Plasma Focus I (TPF-I) is a dense plasma focus device which was developed as a collaborative project among Thailand Institute of Nuclear Technology, Sirindhorn International Institute of Technology and Thammasat university. It aims to be a radiation source for academic research. This device has a power of 6 kJ. In this work, a Rogowski coils was used for measuring high speed current pulse to capture electric signal during operation TPF-I. By determining period of the discharge, it was found that the total inductance of TPF-I is about 216±12 nH, which is in agreement with Lee model.

  19. Unifying Least Squares, Total Least Squares and Data Least Squares

    Czech Academy of Sciences Publication Activity Database

    Paige, C. C.; Strakoš, Zdeněk

    Dordrecht : Kluwer Academic Publishers, 2002 - (van Huffel, S.; Lemmerling, P.), s. 25-34 ISBN 1-4020-0476-1. [International Workshop on TLS and Errore-in-Variables Modelling. Leuven (BE), 27.08.2001-29.08.2001] R&D Projects: GA AV ČR IAA2030801 Grant ostatní: NSERC(CA) OGP0009236 Institutional research plan: AV0Z1030915 Keywords : scaled total least squares * ordinary least squares * data least squares * core problem * orthogonal reduction * singular value decomposition Subject RIV: BA - General Mathematics

  20. International Banking in Cyprus

    OpenAIRE

    Yiallouros, Kristie

    2009-01-01

    The purpose of this dissertation is to analyze the sector of the Cyprus economy that deals with the International Banking or Offshore Banking as otherwise is being called in Cyprus. During the last two decades the island of Cyprus has managed to establish itself as a reputable international financial centre. Therefore the literature review of this paper examines the research theme from two different aspects. First it examines the financial system of Cyprus as related to international ban...

  1. Determinants of International Competiveness

    OpenAIRE

    Hojjat Mehdi

    2014-01-01

    International competitiveness is a main source of economic advancement which results in higher standards of living. This paper examines the determinants of international competitiveness as it defines international competitiveness and discusses two common conceptions that are required to achieve higher level of economic competitiveness: government policies and culture. It further explains a research methodology which is known as Innovation Matrix. Data is collected from two areas: competitiven...

  2. Determinants of International Competiveness

    OpenAIRE

    Hojjat Mehdi

    2014-01-01

    International competitiveness is a main source of economic advancement which results in higher standards of living. This paper examines the determinants of international competitiveness as it defines international competitiveness and discusses two common conceptions that are required to achieve higher level of economic competitiveness: government policies and culture. It further explains a research methodology which is known as “Innovation Matrix”. Data is collected from two areas:  competiti...

  3. Rotor internal friction instability

    Science.gov (United States)

    Bently, D. E.; Muszynska, A.

    1985-01-01

    Two aspects of internal friction affecting stability of rotating machines are discussed. The first role of internal friction consists of decreasing the level of effective damping during rotor subsynchronous and backward precessional vibrations caused by some other instability mechanisms. The second role of internal frication consists of creating rotor instability, i.e., causing self-excited subsynchronous vibrations. Experimental test results document both of these aspects.

  4. Currency Wars & International Trade

    OpenAIRE

    Punabantu, Siize

    2010-01-01

    This paper examines the contemporary international trade and currency system to determine whether the system is appropriate for the level of knowledge, development and maturity of countries today. International trade and currencies are a key mechanism by which governments manage the livelihoods, standard of living and well-being of national economies including the relationship between countries and their peoples. Therefore, understanding how the international trade and currency system works ...

  5. International Macro-Finance

    OpenAIRE

    Pavlova, Anna; Rigobon, Roberto

    2011-01-01

    International macro-finance is a new area of open economy macroeconomics that brings portfolio choice and asset pricing considerations into models of international macroeconomics. The importance of these considerations--typically relegated to Finance and largely overlooked in traditional macroeconomics--for the international macroeconomy have been underscored by a series of recent financial crises and by unprecedented global imbalances. In this paper, we survey recent developments in this are...

  6. International safeguards data authentication

    Energy Technology Data Exchange (ETDEWEB)

    Melton, R.B.; Smith, C.E.; DeLand, S.M.; Manatt, D.R.

    1996-07-01

    The International Safeguards community is becoming increasingly reliant on information stored in electronic form. In international monitoring and related activities it must be possible to verify and maintain the integrity of this electronic information. This paper discusses the use of data authentication technology to assist in accomplishing this task. The paper provides background information, identifies the relevance to international safeguards, discusses issues related to export controls, algorithm patents, key management and the use of commercial vs. custom software.

  7. Internal Audit in Practice

    OpenAIRE

    Havelík, Petr

    2011-01-01

    This thesis deals with the audit and its part is also a execution of own audit. The theoretical part is devoted to the internal audit requirements, to the basic types of the internal audits and other significant characteristics of this discipline, as is especially the code of ethics and the basic methodology of the performing of internal audit. Are also taken into account the specific requirements of the state administration, because the practical part of this thesis deals with the practical ...

  8. Health Care International

    OpenAIRE

    2006-01-01

    This is an interactive quiz for the team representing the Health Care International (HCI) in an educational game to clarify its role and relationship with other provincial reconstruction teams (PRTs), non-governmental organizations (NGOs), and international organizations (IOs) involved in the broad area of humanitarian assistance, relief operations, development and reconstruction in Afghanistan. The educational game involves the following organizations: Health Care International (HCI), Afghan...

  9. Ethics of international collaboration.

    Science.gov (United States)

    Mandal, Jharna; Dinoop, Kp; Parija, Subhash Chandra

    2015-01-01

    Education and research together are vital components of academic institutions and globalization has improved health care education and research in numerous ways, one of which is multinational/transnational research/international collaboration. Usually academic institutions of high-income countries and institutions in low-income countries participate in collaboration. These collaborative research are guided by international ethics codes proposed by the international ethics committee to avoid stringent follow/unethical practices. PMID:25709946

  10. Ethics of international collaboration

    OpenAIRE

    Mandal, Jharna; Dinoop, KP; Parija, Subhash Chandra

    2015-01-01

    Education and research together are vital components of academic institutions and globalization has improved health care education and research in numerous ways, one of which is multinational/transnational research/international collaboration. Usually academic institutions of high-income countries and institutions in low-income countries participate in collaboration. These collaborative research are guided by international ethics codes proposed by the international ethics committee to avoid s...

  11. Editorial: International Entrepreneurial Orientation

    OpenAIRE

    Krzysztof Wach

    2015-01-01

    In recent decades, both the theory of internationalisation of the firm and/or the theory of international business have developed. Recent developments in international business studies prove that entrepreneurial orientation (EO) emerges as one of the important potential factors contributing to the intensification of the processes of internationalisation of the firm (Etemad, 2015; Gupta & Gupta, 2015). It seems that international entrepreneurship (IE) has been flourishing. The general theory o...

  12. International safeguards data authentication

    International Nuclear Information System (INIS)

    The International Safeguards community is becoming increasingly reliant on information stored in electronic form. In international monitoring and related activities it must be possible to verify and maintain the integrity of this electronic information. This paper discusses the use of data authentication technology to assist in accomplishing this task. The paper provides background information, identifies the relevance to international safeguards, discusses issues related to export controls, algorithm patents, key management and the use of commercial vs. custom software

  13. International Trade Price Indices

    OpenAIRE

    Guillaume Gaulier; Julien Martin; Isabelle Méjean; Soledad Zignago

    2008-01-01

    Export and import price indices are useful instruments in international economics. We document here TradePrices, our database of aggregated and sectoral trade price indices for all countries, computed using unit values given by BACI, the CEPII’s database of international trade at the product-level covering the period 1995-2004. Its rich country dimension allow an international comparison of prices evolutions. We compute “common” Laspeyres and Paasche indices but also “superlative” Fisher and ...

  14. Vaccination and Malaria Prevention among International Travelers Departing from Athens International Airport to African Destinations

    OpenAIRE

    Androula Pavli; Athina Spilioti; Paraskevi Smeti; Stavros Patrinos; Maltezou, Helena C.

    2014-01-01

    Background. International travel to Africa has grown dramatically over the last decade along with an increasing need to understand the health issues for travelers. The current survey aimed to assess vaccination and malaria prevention of travelers visiting Africa. Methods. A questionnaire-based survey was conducted from of November 1, 2011 to of April 30, 2013 at Athens International Airport. Results. A total of 360 travelers were studied; 68% were men. Their mean age was 39.9 years. Previous ...

  15. Using the Missing Pin to Challenge Concepts of Refraction and Total Internal Reflection

    Science.gov (United States)

    Tamang, Sushmika; Nopparatjamjomras, Suchai; Chitaree, Ratchapak; Nopparatjamjomras, Thasaneeya R.

    2015-01-01

    A container was placed on top of a piece of white paper, and a pin positioned so that it vertically touched an outside wall of the container. Students were asked to predict the image of the pin when it was observed from the top of the container. Two scenarios of either an empty container or a container completely filled with water were considered…

  16. EM International. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

  17. The Human Genome Project: An Imperative for International Collaboration.

    Science.gov (United States)

    Allende, J. E.

    1989-01-01

    Discussed is the Human Genome Project which aims to decipher the totality of the human genetic information. The historical background, the objectives, international cooperation, ethical discussion, and the role of UNESCO are included. (KR)

  18. Total Productive Maintenance at Paccar INC

    OpenAIRE

    Ştefan Farkas

    2010-01-01

    This paper reports the application of total productive maintenance method at Paccar Inc. truck’s plant in Victoria, Australia. The total productive maintenance method and total productive maintenance house are presented. The global equipment effectiveness is computed and exemplified. The production structure and organising maintenance are presented. Resultas of the variation of global equipment effectiveness and autonomous maintenance in a two weeks period of time are reported.

  19. Total Productive Maintenance at Paccar INC

    Directory of Open Access Journals (Sweden)

    Ştefan Farkas

    2010-06-01

    Full Text Available This paper reports the application of total productive maintenance method at Paccar Inc. truck’s plant in Victoria, Australia. The total productive maintenance method and total productive maintenance house are presented. The global equipment effectiveness is computed and exemplified. The production structure and organising maintenance are presented. Resultas of the variation of global equipment effectiveness and autonomous maintenance in a two weeks period of time are reported.

  20. Development of total-skin electron therapy at two energies

    International Nuclear Information System (INIS)

    Total-Skin Electron Therapy (TSET) modalities have been developed at two energies on a Varian Clinac 1800. The physical criteria for the beams were determined mainly from the requirement of continuing the Stanford treatment technique, which was 12 Total-Skin Electron Therapy portals combined in six pairs. The penetration of the lower energy mode matches that previously obtained at Stanford on the Varian Clinac 10, (about 4 mm for the 80% isodose contour in the 12-field treatment). The penetration of the higher energy mode is about 8 mm at the 80% contour. The Total-Skin Electron Therapy modes necessarily use electrons produced by the two standard electron-beam modes of lowest energy, nominally 6 and 9 MeV. Measurements to verify the beam specifications were carried out with diodes, a variety of ionization chambers, and a specially constructed circular phantom for film dosimetry. Initially, the penetration of the Total-Skin Electron Therapy beams was too large to match our criteria, so two methods of reducing it were explored: (a) the energies of the electron beams produced by the machine were reduced (which also reduced the energies of the corresponding standard electron modes) and (b) a large polymethylmethacrylate degrader (2.4 m X 1.2 m) 1 cm thick was placed just in front of the patient plane. Acceptable Total-Skin Electron Therapy beams could be produced by either method and the latter was finally used. The use of the standard dose monitoring system for the Total-Skin Electron Therapy modes considerably simplifies the daily treatment delivery as well as the implementation. However, the need for reasonable dose rates at the treatment plane (3.5 meters beyond the isocenter) requires dose rates of 24 Gy/min at the isocenter. Nevertheless, it is possible to use the internal dose monitor provided the problems associated with high dose rates are addressed

  1. Patient Matched Instruments and Total Knee System

    Medline Plus

    Full Text Available Smith & Nephew Technologies: VISIONAIRE™ Patient Matched Instruments and LEGION™ Total Knee System You must have Javascript enabled in your web browser. View Program Transcript Click ...

  2. Total pollution effect of urban surface runoff.

    Science.gov (United States)

    Luo, Hongbing; Luo, Lin; Huang, Gu; Liu, Ping; Li, Jingxian; Hu, Sheng; Wang, Fuxiang; Xu, Rui; Huang, Xiaoxue

    2009-01-01

    For pollution research with regard to urban surface runoff, most sampling strategies to date have focused on differences in land usage. With single land-use sampling, total surface runoff pollution effect cannot be evaluated unless every land usage spot is monitored. Through a new sampling strategy known as mixed stormwater sampling for a street community at discharge outlet adjacent to river, this study assessed the total urban surface runoff pollution effect caused by a variety of land uses and the pollutants washed off from the rain pipe system in the Futian River watershed in Shenzhen City of China. The water quality monitoring indices were COD (chemical oxygen demand), TSS (total suspend solid), TP (total phosphorus), TN (total nitrogen) and BOD (biochemical oxygen demand). The sums of total pollution loads discharged into the river for the four indices of COD, TSS, TN, and TP over all seven rainfall events were very different. The mathematical model for simulating total pollution loads was established from discharge outlet mixed stormwater sampling of total pollution loads on the basis of four parameters: rainfall intensity, total land area, impervious land area, and pervious land area. In order to treat surface runoff pollution, the values of MFF30 (mass first flush ratio) and FF30 (first 30% of runoff volume) can be considered as split-flow control criteria to obtain more effective and economical design of structural BMPs (best management practices) facilities. PMID:19999964

  3. Generalized gravitational entropy from total derivative action

    Science.gov (United States)

    Dong, Xi; Miao, Rong-Xin

    2015-12-01

    We investigate the generalized gravitational entropy from total derivative terms in the gravitational action. Following the method of Lewkowycz and Maldacena, we find that the generalized gravitational entropy from total derivatives vanishes. We compare our results with the work of Astaneh, Patrushev, and Solodukhin. We find that if total derivatives produced nonzero entropy, the holographic and the field-theoretic universal terms of entanglement entropy would not match. Furthermore, the second law of thermodynamics could be violated if the entropy of total derivatives did not vanish.

  4. Generalized Gravitational Entropy from Total Derivative Action

    CERN Document Server

    Dong, Xi

    2015-01-01

    We investigate the generalized gravitational entropy from total derivative terms in the gravitational action. Following the method of Lewkowycz and Maldacena, we find that the generalized gravitational entropy from total derivatives vanishes. We compare our results with the work of Astaneh, Patrushev, and Solodukhin. We find that if total derivatives produced nonzero entropy, the holographic and the field-theoretic universal terms of entanglement entropy would not match. Furthermore, the second law of thermodynamics could be violated if the entropy of total derivatives did not vanish.

  5. WHO International EMF Project

    International Nuclear Information System (INIS)

    WHO International EMF Project is to Review the scientific literature on health effects of EMF exposure and formally assess health risks; Promote a focused agenda of high quality EMF research; Encourage internationally acceptable harmonized standards; Provide information on risk perception, risk communication, risk management

  6. Developing Productive International Teams.

    Science.gov (United States)

    Hanson, Diane C.

    1999-01-01

    Describes ways to develop productive international teams in the international marketplace. Discusses obstacles, including language and distance; a model for effective global team performance; cultural differences; shared goals; communication; lack of information; leadership; work procedures; compensation; lack of knowledge or skills; and hindered…

  7. Sovereignty in International Law

    Directory of Open Access Journals (Sweden)

    Jana MAFTEI

    2015-03-01

    Full Text Available We aimed at highlighting in this paper, after analyzing the transformations that took place in the international society, the importance of a particularly sensitive and current topic for public international law, namely the sovereignty. A political and legal concept at the same time, the state sovereignty remains permanently into the attention of researchers in an attempt to determine its role in international relations governed by the international law. The concept of sovereignty is complex, it can be analyzed in terms of the national law, but as a member of international society, a State participates in international relations on the basis of sovereign equality principle, which causes another meaning of sovereignty, which completes the one specific to the internal life. We have analyzed the evolution of the concept of sovereignty and we have identified the causes that led to changes in its characteristics, in order to predict the tendencies in its development. We have highlighted the aspects of the exercise of sovereignty as a result of limiting the powers of state in the favor of international bodies. In preparing this article we have used as research methods the analysis of the problems generated by mentioned subject with reference to the doctrinal views expressed in specialized papers, documentary research, and interpretation of legal norms in the field.

  8. Microinertia and internal variables

    CERN Document Server

    Berezovski, A

    2015-01-01

    The origin of microinertia of micromorphic theories is investigated from the point of view of non-equilibrium thermodynamics. In the framework of dual internal variables microinertia stems from a thermodynamic equation of state related to the internal variable with the properties of mechanical momentum.

  9. Internal Audit Classification

    OpenAIRE

    Mirela Claudia MITAC

    2007-01-01

    The intern audit has an important role in economy. There is any institution without a risky activity. The goal of this paper is to show the importance of intern audit in providing an independent evaluation of risk management, of controlling and of process management.

  10. BWR internal cracking issues

    International Nuclear Information System (INIS)

    The regulatory issues associated with cracking of boiling water reactor (BWR) internals is being addressed by the Nuclear Regulatory Commission (NRC) staff and is the subject of a voluntary industry initiative. The lessons learned from this effort will be applied to pressurized water reactor (PWR) internals cracking issues

  11. Research in International Education

    Science.gov (United States)

    Dolby, Nadine; Rahman, Aliya

    2008-01-01

    Until recently, international education has existed at the margins of educational research. However, in the current context of globalization, international education has moved closer to the center of educational research throughout the world. In this article, the authors identify, describe, and analyze six distinct research approaches to…

  12. Publishing International Counseling Articles

    Science.gov (United States)

    Hohenshil, Thomas H.; Amundson, Norman E.

    2011-01-01

    This article begins with a rationale for including international articles in the "Journal of Counseling & Development." Then, 2 general categories of international articles are described. First are articles that provide a general overview of counseling in a particular country. The 2nd category is more general and might involve international…

  13. International Entrepreneurship and Sourcing

    DEFF Research Database (Denmark)

    Servais, Per; Zucchella, Antonella; Palamera, Giada

    2006-01-01

    This contribution focuses on international sourcing as an entrepreneurial act and aims at demonstrating that it is actually at the core of internationalization processes of small firms, both established and international new ventures. Another issue of this research is to understand how these firm...

  14. International Geomagnetic Reference Field

    DEFF Research Database (Denmark)

    Finlay, Chris; Maus, S.; Beggan, C. D.;

    2010-01-01

    The eleventh generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2009 by the International Association of Geomagnetism and Aeronomy Working Group V‐MOD. It updates the previous IGRF generation with a definitive main field model for epoch 2005.0, a main field...

  15. Interne eller eksterne ledere?

    DEFF Research Database (Denmark)

    Boyd, Britta; Royer, Susanne

    2013-01-01

    used internal successors for the last 12 successions. We argue that in industries where tacit knowledge forms the basis for competitive advantage, the use of internal successors can help family firms excel after a transition of power has occurred. Theoretical and practical implications are discussed to...

  16. Embracing an International Board

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A new international stock board will soon be established in Shanghai,allowing foreign companies to list their businesses and tap into the China market China is moving closer to launching its own international stock board,a market for foreign companies to list their stocks in China,said Shang Fulin,

  17. Unilateralism in International Law

    DEFF Research Database (Denmark)

    Hartmann, Jacques

    2015-01-01

    international law. This note considers when and how a State or a regional organisation may legitimately take unilateral measures to protect the environment. The note will does not consider the legality of including foreign aircraft within the ETS, which has been dealt with elsewhere. Instead, it will focus on...... the legality and importance of unilateral acts for the development of international law....

  18. FINANCING OF INTERNATIONAL TRANSACTIONS

    Directory of Open Access Journals (Sweden)

    RADU NICOLAE BĂLUNĂ

    2013-02-01

    Full Text Available Financing (funding is essentially the purchase of funds necessary for a business. This can be done from internal sources (company’s own funds or external (borrowed funds. The high value of goods traded in international trade makes revenues generated from internal resources not sufficient to settle the value of the goods. Thus, it is frequent to resort to borrowed funds. In International Business Transactions, external financing is done both by classical techniques of credit (credit supplier and buyer credit and modern techniques of financing (factoring, forfeiting, leasing all trade tailored. In terms of the length of financing, accounting funding is short-term (1-12 months and long-term financing (over a year. In principle, export and import operations prevailing short-term financing techniques, while international investment and industrial cooperation actions are specific long-term funding

  19. International Fisheries Agreements

    DEFF Research Database (Denmark)

    Pintassilgo, Pedro; Kronbak, Lone Grønbæk; Lindroos, Marko

    2015-01-01

    This paper surveys the application of game theory to the economic analysis of international fisheries agreements. The relevance of this study comes not only from the existence of a vast literature on the topic but especially from the specific features of these agreements. The emphasis of the survey...... is on coalition games, an approach that has become prominent in the fisheries economics literature over the last decade. It is shown that coalition games were first applied to international fisheries agreements in the late 1990s addressing cooperative issues under the framework of characteristic...... formation and stability of international fisheries agreements. A key message that emerges from this literature strand is that self-enforcing cooperative management of internationally shared fish stocks is generally difficult to achieve. Hence, the international legal framework and regulations play a...

  20. Attracting International Hotels

    DEFF Research Database (Denmark)

    Assaf, A. George; Josiassen, Alexander; Agbola, Frank Wogbe

    2015-01-01

    their presence has several positive effects. Using, for the first time, actual on-location data we investigate the factors that matter most for international hotels when selecting host destinations. Specifically, we identify 23 factors that make a destination an attractive (or unattractive) location......With the increased international competition facing hotel chains, it is essential that the next destination they enter is the most attractive option possible. The host destinations too have a keen interest in strategically positioning themselves in order to attract international hotels since...... for international hotels. We then rank these. The results show that welcomeness, infrastructure, and crime rate are the three most important factors that influence the location of international hotels in host destinations....

  1. Internal pump monitoring device

    International Nuclear Information System (INIS)

    In the present invention, a thermometer is disposed at the upper end of an internal pump casing of a coolant recycling system in a BWR type reactor to detect leakage of reactor water thereby ensuring the improvement of reliability of the internal pump. Namely, a thermometer is disposed, which can detect temperature elevation occurred when water in the internal pump leaked from a reactor pressure vessel passes through the gap between a stretch tube and an upper end of the pump casing. Signals from the thermometer are transmitted to a signal processing device by an instrumentation cable. The signal processing device generates an alarm when the temperature signal exceeds a predetermined value and announces that leakage of reactor water occurs in the internal pump. Since the present invention can detect the leakage of the reactor water in the pump casing in an early stage, it can contribute to the improvement of the safety and reliability of the internal pump. (I.S.)

  2. Cancer from internal emitters

    International Nuclear Information System (INIS)

    Irradiation from internal emitters, or internally deposited radionuclides, is an important component of radiation exposures encountered in the workplace, home, or general environment. Long-term studies of human populations exposed to various internal emitters by different routes of exposure are producing critical information for the protection of workers and members of the general public. The purpose of this report is to examine recent developments and discuss their potential importance for understanding lifetime cancer risks from internal emitters. The major populations of persons being studied for lifetime health effects from internally deposited radionuclides are well known: Lung cancer in underground miners who inhaled Rn progeny, liver cancer from persons injected with the Th-containing radiographic contrast medium Thorotrast, bone cancer from occupational or medical intakes of 226Ra or medical injections of 224Ra, and thyroid cancer from exposures to iodine radionuclides in the environment or for medical purposes

  3. Immunity of international organizations

    CERN Document Server

    Schrijver, Nico

    2015-01-01

    Immunity rules are part and parcel of the law of international organizations. It has long been accepted that international organizations and their staff need to enjoy immunity from the jurisdiction of national courts. However, it is the application of these rules in practice that increasingly causes controversy. Claims against international organizations are brought before national courts by those who allegedly suffer from their activities. These can be both natural and legal persons such as companies. National courts, in particular lower courts, have often been less willing to recognize the immunity of the organization concerned than the organization s founding fathers. Likewise, public opinion and legal writings frequently criticize international organizations for invoking their immunity and for the lack of adequate means of redress for claimants. It is against this background that an international conference was organized at Leiden University in June 2013. A number of highly qualified academics and practit...

  4. Minority International Research Training Program: Global Collaboration in Nursing Research.

    Science.gov (United States)

    McElmurry, Beverly J.; Misner, Susan J.; Buseh, Aaron G.

    2003-01-01

    The Minority International Research Training Program pairs minority nursing students with faculty mentors at international sites for short-term research. A total of 26 undergraduate, 22 graduate, and 6 postdoctoral students have participated. Challenges include recruitment, orientation, and preparation of students; identification and preparation…

  5. Timing the total reflection of light

    International Nuclear Information System (INIS)

    We have identified for the first time the absolute delay at total reflection, envisioned by Newton. We show that there are in fact two divergent Wigner delays, depending on the polarisation of the incident light. These measurements give a new insight on the passage from total reflection to refraction

  6. Total cardiovascular disease risk assessment: a review.

    LENUS (Irish Health Repository)

    Cooney, Marie Therese

    2011-09-01

    The high risk strategy for the prevention of cardiovascular disease (CVD) requires an assessment of an individual\\'s total CVD risk so that the most intensive risk factor management can be directed towards those at highest risk. Here we review developments in the assessment and estimation of total CVD risk.

  7. Sexuality after total vs. subtotal hysterectomy

    DEFF Research Database (Denmark)

    Zobbe, Vibeke Bahn; Gimbel, Helga Margrethe Elisabeth; Andersen, Birthe Margrethe;

    2004-01-01

    The effect of hysterectomy on sexuality is not fully elucidated and until recently total and subtotal hysterectomies have only been compared in observational studies.......The effect of hysterectomy on sexuality is not fully elucidated and until recently total and subtotal hysterectomies have only been compared in observational studies....

  8. A note on totally normal spaces

    International Nuclear Information System (INIS)

    In this note we give the necessary and sufficient condition for a topological space X such that the product space X x Y is totally normal for any (non discrete) metric space Y, and we show that a totally normal p-space need not be a perfectly normal in general, which makes Theorem 2 doubtful. (author). 6 refs

  9. Simultaneous and staged bilateral total hip arthroplasty

    DEFF Research Database (Denmark)

    Lindberg-Larsen, Martin; Joergensen, Christoffer Calov; Husted, Henrik;

    2013-01-01

    Bilateral total hip arthroplasty (BTHA) and bilateral simultaneous total hip arthroplasty (BSTHA) are done increasingly. Previous studies evaluating outcomes after bilateral procedures have found different results. The aim of this study was to investigate length of hospital stay (LOS), 30 days...

  10. 75 FR 22418 - FHA TOTAL Mortgage Scorecard

    Science.gov (United States)

    2010-04-28

    ... URBAN DEVELOPMENT FHA TOTAL Mortgage Scorecard AGENCY: Office of the Chief Information Officer, HUD... samples at FHA's request, and appeals in writing for loss of privilege to use the scorecard. DATES... following information: Title of Proposal: FHA TOTAL Mortgage Scorecard. OMB Approval Number: 2502-0556....

  11. Comparison of Recent Total Irradiance Measurements

    Science.gov (United States)

    Helizon, R.; Pap, J.

    2002-12-01

    Total solar irradiance has been measured since 1978 from various satellites. Since the absolute accuracy of the current irradiance measurements is about 0.2%, one needs to compile composite irradiance time series to study long-term changes and to establish whether there are any secular variations over the last two and half decades. In this paper we compare the UARS/ACRIM II and SOHO/VIRGO total irradiance data as well as the SOHO/VIRGO and ACRIM III total irradiance. Our main goal is to validate the newly processed ACRIM II total irradiance. Comparison of the SOHO/VIRGO and ACRIM III data will also help to establish whether the high total irradiance values for the maximum of solar cycle 23 represent real solar, rather than, instrumental events.

  12. Perspectives of Turkish Intern and Non-Intern Students towards Sport Management Internship within the Context of Field Experience

    Science.gov (United States)

    Coknaz, Dilsad

    2014-01-01

    The purpose of this study was to examine differences between intern and non-intern students in terms of their perspectives on sport management internship within the context of field experience. The subjects of the study were a total of 189 students. They were 4th year students who completed their internship and 3rd year students who were yet to…

  13. Development of an Electrohydraulic Total Artificial Heart System

    Science.gov (United States)

    Homma, Akihiko; Taenaka, Yoshiyuki; Tatsumi, Eisuke; Takewa, Yoshiaki; Mizuno, Toshihide; Shioya, Kyoko; Lee, Hwan Sung; Tsukiya, Tomonori; Kakuta, Yukihide; Katagiri, Nobumasa; Nishinaka, Tomohiro; Koshiji, Kohji

    An electrohydraulic total artificial heart (EHTAH) system has been developed. The EHTAH system consists of diaphragm-type blood pumps, an electrohydraulic actuator, an internal control unit, a transcutaneous energy transfer system (TETS), a transcutaneous optical telemetry system (TOTS), and an internal battery. The reciprocating rotation of the impeller generates oil pressure which drives the blood pumps at alternating intervals. The blood pumps and the actuator were successfully integrated into the pump unit without oil conduits. As a result of miniaturizing the blood pumps and the actuator, the displacement volume and weight of the EHTAH system decreased to 872 ml and 2492g, respectively. Furthermore, the maximum flow rate and efficiency increased up to 12 L/min and 15.4%. The pump units and the EHTAH systems were successfully implanted in 36 calves weighing from 55 to 87kg. In the longest case, the ca1f with the pump unit survived for 87 days and the calf with the EHTAH system survived for 70 days. The EHTAH system was powered by the TETS, and was powered everyday by the internal battery for 40 minutes. These results indicate that the EHTAH system has the potential to become a fully implantable cardiac replacement system.

  14. NASA International Environmental Partnerships

    Science.gov (United States)

    Lewis, Pattie; Valek, Susan

    2010-01-01

    For nearly five decades, the National Aeronautics and Space Administration (NASA) has been preeminent in space exploration. NASA has landed Americans on the moon, robotic rovers on Mars, and led cooperative scientific endeavors among nations aboard the International Space Station. But as Earth's population increases, the environment is subject to increasing challenges and requires more efficient use of resources. International partnerships give NASA the opportunity to share its scientific and engineering expertise. They also enable NASA to stay aware of continually changing international environmental regulations and global markets for materials that NASA uses to accomplish its mission. Through international partnerships, NASA and this nation have taken the opportunity to look globally for solutions to challenges we face here on Earth. Working with other nations provides NASA with collaborative opportunities with the global science/engineering community to explore ways in which to protect our natural resources, conserve energy, reduce the use of hazardous materials in space and earthly applications, and reduce greenhouse gases that potentially affect all of Earth's inhabitants. NASA is working with an ever-expanding list of international partners including the European Union, the European Space Agency and, especially, the nation of Portugal. Our common goal is to foster a sustainable future in which partners continue to explore the universe while protecting our home planet's resources for future generations. This brochure highlights past, current, and future initiatives in several important areas of international collaboration that can bring environmental, economic, and other benefits to NASA and the wider international space community.

  15. Pharyngocutaneous fistula onset after total laryngectomy: scintigraphic analysis.

    Science.gov (United States)

    Galli, J; Valenza, V; Parrilla, C; Galla, S; Marchese, M R; Castaldi, P; Almadori, G; Paludetti, G

    2009-10-01

    Pharyngocutaneous fistula is the most common non-fatal complication following total laryngectomy. To start oral feeding and exclude the presence of a pharyngocutaneous fistula, a subjective test and instrumental assessments using videofluoroscopy, have been described. The aim of this study was to evaluate the effectiveness of oral-pharyngo-oesophageal scintigraphy as an objective and non-invasive tool to establish presence, site and dimensions of the fistula. Observations were performed on 3 male patients, mean age 65 years, who underwent total laryngectomy and mono or bilateral neck dissection after failure of radiotherapy in 2 cases and of conservative laryngeal surgery in the third case, complicated by post-operative pharyngocutaneous fistula. Oral-pharyngo-oesophageal scintigraphy dynamic study with sequential images were obtained during the swallowing phases. In case 1, the test showed a wide pharyngocutaneous fistula the internal orifice of which was at the level of the base of the tongue: on the scintigraphic images, the radiomarked water bolus, from the fistulous orifice, descended along the stoma walls and only a small part reached the oesophagus. In the other two patients, the pharyngocutaneous fistula was small and the internal fistulous orifice was detected in the lower part of T-suture line. In conclusion, scintigraphy offered the possibility to precisely identify presence of pharyngocutaneous fistula and location of its internal orifice and to monitor its spontaneous closure. Therefore, important information could be obtained regarding the suture line status and the possibility of deciding whether to remove the nasogastric tube or to leave it in place. Finally, these data showed that oral-pharyngo-oesophageal scintigraphy could be performed in the early post-operative period to optimize starting safe oral feeding. PMID:20162023

  16. Generalized internal multiple imaging

    KAUST Repository

    Zuberi, M. A. H.

    2014-08-05

    Internal multiples deteriorate the image when the imaging procedure assumes only single scattering, especially if the velocity model does not have sharp contrasts to reproduce such scattering in the Green’s function through forward modeling. If properly imaged, internal multiples (internally scattered energy) can enhance the seismic image. Conventionally, to image internal multiples, accurate, sharp contrasts in the velocity model are required to construct a Green’s function with all the scattered energy. As an alternative, we have developed a generalized internal multiple imaging procedure that images any order internal scattering using the background Green’s function (from the surface to each image point), constructed from a smooth velocity model, usually used for conventional imaging. For the first-order internal multiples, the approach consisted of three steps, in which we first back propagated the recorded surface seismic data using the background Green’s function, then crosscorrelated the back-propagated data with the recorded data, and finally crosscorrelated the result with the original background Green’s function. This procedure images the contribution of the recorded first-order internal multiples, and it is almost free of the single-scattering recorded energy. The cost includes one additional crosscorrelation over the conventional single-scattering imaging application. We generalized this method to image internal multiples of any order separately. The resulting images can be added to the conventional single-scattering image, obtained, e.g., from Kirchhoff or reverse-time migration, to enhance the image. Application to synthetic data with reflectors illuminated by multiple scattering (double scattering) demonstrated the effectiveness of the approach.

  17. Radiation survey in the International Space Station

    OpenAIRE

    Narici Livio; Casolino Marco; Di Fino Luca; Larosa Marianna; Picozza Piergiorgio; Zaconte Veronica

    2015-01-01

    The project ALTEA-shield/survey is part of an European Space Agency (ESA) – ILSRA (International Life Science Research Announcement) program and provides a detailed study of the International Space Station (ISS) (USLab and partly Columbus) radiation environment. The experiment spans over 2 years, from September 20, 2010 to September 30, 2012, for a total of about 1.5 years of effective measurements. The ALTEA detector system measures all heavy ions above helium and, to a limited extent, hydro...

  18. International Institutions and GHG

    Institute of Scientific and Technical Information of China (English)

    Jin Jiyong

    2008-01-01

    Globalization is pushing public health crises beyond traditional national boundaries. It has also transformed international health governance into global health governance. Health security is one aspect of global public welfare. International institutions, such as the WHO, the WTO, the World Bank, and the BWC, are main providers of global public welfare for health. However, those institutions' role in global health governance is not optimized. An analysis of the shortcomings of the international institutions concerned with global heath can contribute to better global health governance. Some tentative solutions to such problems are put forward in this paper.

  19. International energy annual 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power, geothermal, solar, and wind electric power, biofuels energy for the US, and biofuels electric power for Brazil. New in the 1996 edition are estimates of carbon dioxide emissions from the consumption of petroleum and coal, and the consumption and flaring of natural gas. 72 tabs.

  20. The international development challenge

    International Nuclear Information System (INIS)

    Markets are opening up to international competition and new opportunities will arise for companies. The first part of this international round table of the French gas association's annual conference was devoted to whether they have all necessary assets, especially in terms of know-how and new technologies. In the second part of this round table, gas industry leaders presented their ambitions and strategies on the international scene. The questions discussed related to the main areas of development from both business and geographic viewpoints; to the underlying factors such as expertise, technological know-how, market risks and potential, strategic alliances. (authors)

  1. International petroleum statistics report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report presents data on international oil production, demand, imports, exports and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). Section 2 presents an oil supply/demand balance for the world, in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries.

  2. Society - Totally Dependent upon ICT? Introduction to the CIP-2010 Conference Proceedings

    OpenAIRE

    Caelli, William

    2010-01-01

    At the 50 th anniversary of the formation of the International Federation for Information Processing the simple fact that national economies and international commerce alike have become totally dependent upon the reliable and secure operation of national and global information infrastructures has been accepted. Moreover, the realization that societies are moving towards so-called "digital economies" has been acknowledged by all, from the citizen to the highest leader of a nation. From the ear...

  3. Integration of Public Finance Administration into ISO 9001 Total Quality Management

    OpenAIRE

    KİTAPÇI, Hakan; ERDOĞAN, ÖMER

    2012-01-01

    In Chronology; although they show different progress from each others, today Total Quality Management (TQM) and Internal Auditing are two management concepts that are in mutual interaction and provide help for development of each other. TQM is a human based management concept that aims to increase customer satisfaction and enhance quality with decreasing cost in organizations. Internal Auditing is an independent, objective assurance and consultancy action on organization’s efficiency, product...

  4. Total dominator chromatic number of a graph

    Directory of Open Access Journals (Sweden)

    Adel P. Kazemi

    2015-06-01

    Full Text Available Given a graph $G$, the total dominator coloring problem seeks a proper coloring of $G$ with the additional property that every vertex in the graph is adjacent to all vertices of a color class. We seek to minimize the number of color classes. We initiate to study this problem on several classes of graphs, as well as finding general bounds and characterizations. We also compare the total dominator chromatic number of a graph with the chromatic number and the total domination number of it.

  5. (d,1)-total labelling of graphs

    OpenAIRE

    Havet, Frédéric; Yu, Min-Li

    2002-01-01

    A $(d,1)$-total labelling of a graph $G$ is an assignment of integers to $V(G)\\cup E(G)$ such that: (i) any two adjacent vertices of $G$ receive distinct integers, (ii) any two adjacent edges of $G$ receive distinct integers, and (iii) a vertex and its incident edge receive integers that differ by at least $d$ in absolute value. The {\\it span} of a $(d,1)$-total labelling is the maximum difference between two labels. The minimum span of a $(d,1)$-total labelling of $G$ is denoted by $\\lambda_...

  6. International petroleum statistics report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    This report presents data on international oil production, demand, imports, and stocks. World oil production and OECD demand data are for the years 1970 through 1995; stocks from 1973 through 1995, and trade from 1985 through 1995.

  7. Galaxy International Mall Unveiled

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    An agreement between Galaxy International Mall (hereinafter referred to as Galaxy) and its three main partners was signed on January 12, 2011, in the city of Tianjin. The partners are Lotte Department

  8. International Committee expands structure

    Science.gov (United States)

    Bush, Susan

    AGU's Committee on International Participation has recently undergone a restructuring, or “perestroika,” according to International Secretary Juan Roederer. By establishing the new ad hoc Regional Advisory Committees (RACs) and Corresponding Members, AGU will help assure that it is serving its worldwide membership and strengthening its international relations.The CIP, through the new RACs, will identify the needs of geophysicists outside the United States and Canada and add services not currently available and enhance existing services. The International Secretary will then make recommendations to the appropriate AGU program and administrative committees. The CIP may also propose special activities such as the ongoing Berkner Membership Program for developing countries and the Latin America Visiting Scientist Program.

  9. Travelers' Health: International Adoption

    Science.gov (United States)

    ... any child with fever and bloody diarrhea. Unlike refugees, internationally adopted children are not treated for parasites ... disease is endemic throughout much of Mexico, Central America, and South America (Chapter 3, Trypanosomiasis, American (Chagas ...

  10. Intern kommunikation under forandring

    DEFF Research Database (Denmark)

    Aggerholm, Helle; Asmuss, Birte; Ditlevsen, Marianne Grove;

    Intern kommunikation under forandring giver en teoretisk og praktisk indføring i de tekster, genrer og kommunikationsformer, som den interne kommunikation i private og offentlige virksomheder eller organisationer typisk omfatter. Dertil kommer en indføring i opfattelser af kommunikation......, organisation og ledelse, som er relevante for arbejdet med den interne kommunikation. Bogen beskæftiger sig med intern kommunikation i bred forstand, dvs. med tekster og genrer, der ikke kun produceres af kommunikationsafdelingen, men også af ledelse, medarbejdere og HR-afdeling. Blandt bogens emner kan nævnes......: mission og vision statements, kommunikationspolitik, kommunikationsplanlægning, linjekommunikation, personalebladet, intranettet, årsrapporten og kommunikation i forbindelse med rekruttering, medarbejderudvikling og afskedigelse. Bogen henvender sig til kommunikationsstuderende på BA- og kandidatniveau...

  11. Melanoma International Foundation

    Science.gov (United States)

    ... 501(c)(3) charity, also registered as a non-profit charity in the state of Pennsylvania, certificate #29498 © 2013 Melanoma International Foundation. All Rights Reserved. Privacy Policy | Terms of Use ...

  12. International Baccalaureate Physics

    Science.gov (United States)

    Votta, P.

    1993-05-01

    The International Baccalaureate has long been recognized for providing breadth in 16-18 education. This article examines whether it can also provide the depth to match A-levels by comparing IB Higher Physics with A-level Physics.

  13. International Lymphoma Epidemiology Consortium

    Science.gov (United States)

    The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

  14. International Myeloma Foundation

    Science.gov (United States)

    ... voices • about imf about us people of IMF international partners imf funded ... of the IMWG Tackle Soaring Costs of Care >> Takeda Receives Marketing Authorization in Canada for NINLARO™ (ixazomib) in Relapsed/ ...

  15. CNPC International Research Center

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ CNPC International Research Center (CNPCIRC), jointly managed by CNODC and RIPED of China National Petroleum Corporation (CNPC), was established in 1999 for providing technical research support to all the overseas oil and gas projects of CNPC.

  16. NCEP Internal Office Notes

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Centers for Environmental Prediction (NCEP) and its predecessors have produced internal publications, known as Office Notes, since the mid-1950's. In...

  17. International standards in metallurgy

    Institute of Scientific and Technical Information of China (English)

    Fomina; O.; N.

    2005-01-01

    The existence of incompatible standards in many technical fields represents a technical barrier to international cooperation between enterprises in different countries in the manufacture of high technology products.……

  18. Office of International Research, Education, and Development garners $30 million from U.S. Agency for International Development for two global projects

    OpenAIRE

    Rich, Miriam Sommers

    2009-01-01

    S.K. De Datta, associate vice president for international affairs and director of Virginia Tech's Office of International Research, Education, and Development, has announced that the U.S. Agency for International Development (USAID) has renewed two five-year grants totaling $30 million.

  19. Magnetic Field - Secular Variation of the Total Field Component for the Epoch 2010.0 - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer shows lines of equal annual change (secular variation), in the total field intensity of the Earth's magnetic field, derived from the International...

  20. International cooperation and exchange

    International Nuclear Information System (INIS)

    To draw extensively the international experience for application and enhance the surveillance level on nuclear safety in the country, the NNSA dispatched abroad 30 delegations including 56 person-time and invited 9 delegations in 1999. The dispatched items included mainly the international meetings on nuclear safety, the surveillance on foreign equipment and the personnel technical training; the invited items included mainly the consultation and lectures on regulatory techniques and the consultation with the review and assessment on the experimental fast reactor

  1. International petroleum statistics report

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    This monthly publication provides current international oil data. The Report presents data on international oil production, demand, imports, exports, and stocks. Section 1 contains time series data on world oil production, and on oil demand and stocks in the OECD. Section 2 presents an oil supply/demand balance for the world. Section 3 presents data on oil imports by OECD countries. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries.

  2. International energy outlook, 1993

    International Nuclear Information System (INIS)

    This report presents the current Energy Information Administration (EIA) assessment of the long-term outlook for international energy markets. This and other EIA reports are provided as a statistical service for use by managers and international energy analysts, not as a Government energy plan. Current US Government policies and foreign government policies are assumed to hold over the projection interval, which extends to the year 2010

  3. China's International Responsibility Examined

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    International responsibility falls upon the shoulders of every country. China's growing contributions to world peace and development have surpassed the view of her as a "threat. "Instead, it was, among world mainstream opinion, expected to shoulder a still-bigger burden. Such external expectations, together with internal yearnings for a higher profile abroad, urge a response in terms of Chinese diplomacy. What is to be done? This paper explores the answer.

  4. International Comparisons of GDP

    OpenAIRE

    Ian Castles; David Henderson

    2005-01-01

    When it comes to making international comparisons of real GDP, different views, conventions and practices are still in evidence. The authors set out the case for using purchasing power parity (PPP) converters for this purpose, rather than conversions based on exchange rates, and give reasons for rejecting various arguments that are still widely made to the contrary. In doing so, they provide instances of the differing current practices of international agencies, and argue the case for greater...

  5. International Production and Employment

    OpenAIRE

    Anca-Mihaela TEAU; Cristina Elena PROTOPOPESCU

    2013-01-01

    The present article analyses the impact of an integrated international production system on the quantity and quality of employment, human resource development and, more generally, to the organization of work. As created assets have become more and more important in international competitiveness, employment effects (e.g., human resource development, industrial relations) associated with transnational corporations are of great interest to all host countries, in particular developing countries.

  6. Hiboo International Football Cup

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The Hiboo International Cup Soccer Friendly, sponsored by the Hiboo International Group, kicked off on May 13 in Dongguangtou, Fengtai District, Beijing. The event will last until June 10 when the first whistle blows at the FIFA 2006 World Cup games in Germany, and provides the perfect teaser for local soccer fans to get in the World Cup mood. The Hiboo Cup is played between teams from China and seven foreign embassies' representatives, from the United States, Mexico, France, the African Union, Malaysia,...

  7. Marketing Consulting Services Internationally

    OpenAIRE

    Waltz, L E

    1986-01-01

    This paper seeks to examine most of the following types of concerns that an independent consultant would have to face up to in seeking to market his services in the international arena: the nature of independent consulting for international organizations; how the services may be marketed; how they may be packaged; how to finance them; how to price aggressively but competitively and how to use the available marketing tools of the related professions. Additionally, how to assess risks, risk ave...

  8. EFFEKTIVISERING AV INTERN MATERIALHANTERING

    OpenAIRE

    Ishak, Martin; Andersson, Andreas

    2013-01-01

    Considering that the current technology is constantly improving, it becomes increasingly important to have an efficient logistics in a company to maintain profitability while achieving a competitive business. Efficient logistics may be accomplished by improving the internal materials handling. In this thesis the internal material handling of steel frames has been studied at a factory in Vaggeryd. The goal of this study is to investigate the problems that exist with the current production flow...

  9. Risk in International Business

    OpenAIRE

    Canavan, Deirdre; Sharkey Scott, Pamela

    2012-01-01

    Risk in international business can stress risk adverse behaviour to counteract foreign market uncertainty or individual entrepreneurial risk taking behaviour dependent on the characteristics of both the business sector and the individual. International business theory would suggest that the perception of risk may differ in situations including where new market entry is incremental, is taken in larger or earlier stages, or indeed whether it may be experienced in a continually fluctuating manne...

  10. The International Heliophysical Year

    OpenAIRE

    Davila, Joseph M.; Thompson, Barbara J.; Gopalswamy, Nat

    2009-01-01

    The International Geophysical Year (IGY) of 1957, a broad-based and all-encompassing effort to push the frontiers of geophysics, resulted in a tremendous increase of knowledge in space physics, Sun-Earth Connection, planetary science and the heliosphere in general. Now, 50 years later, we have the unique opportunity advance our knowledge of the global heliosphere and its interaction with planetary bodies and the interstellar medium through the International Heliophysical Year (IHY) in 2007. T...

  11. Marketing CANDU internationally

    International Nuclear Information System (INIS)

    The market for CANDU reactor sales, both international and domestic, is reviewed. It is reasonable to expect that between five and ten reactors can be sold outside Canada before the end of the centry, and new domestic orders should be forthcoming as well. AECL International has been created to market CANDU, and is working together with the Canadian nuclear industry to promote the reactor and to assemble an attractive package that can be offered abroad. (L.L.)

  12. Waardenburg's syndrome associated with total aganglionosis.

    OpenAIRE

    Farndon, P A; Bianchi, A.

    1983-01-01

    A Pakistani child of consanguineous parents had signs of Waardenburg's syndrome and total intestinal aganglionosis. This association seems to be a distinct clinical entity with an autosomal recessive mode of inheritance.

  13. Patient Matched Instruments and Total Knee System

    Medline Plus

    Full Text Available Smith & Nephew Technologies: VISIONAIRE™ Patient Matched Instruments and LEGION™ Total Knee System You must have Javascript enabled in your web browser. View Program Transcript Click Here to view the OR-Live, Inc. Privacy Policy and Legal ...

  14. Enantioselective Total Synthesis of (+)-Gliocladin C

    OpenAIRE

    Overman, Larry E.; Shin, Youseung

    2007-01-01

    The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product.

  15. Concise Enantiospecific Total Synthesis of Tubingensin A

    OpenAIRE

    Goetz, Adam E.; Silberstein, Amanda L.; Corsello, Michael A.; Garg, Neil K.

    2014-01-01

    We report the enantiospecific total synthesis of (+)-tubingensin A. Our synthesis features an aryne cyclization to efficiently introduce the vicinal quaternary stereocenters of the natural product and proceeds in only nine steps (longest linear sequence) from known compounds.

  16. Total Knee System with Patient Matched Instrumentation

    Medline Plus

    Full Text Available LEGION™ Total Knee System with VISIONAIRE™ Patient Matched Instrumentation You must have Javascript enabled in your web browser. View Program Transcript Click Here to view the OR-Live, Inc. ...

  17. Total Synthesis of (±)-Hibiscone C

    OpenAIRE

    Ungureanu, Sinziana; Meadows, Maggie; Smith, Joel; Duff, David B.; Burgess, James M.; Goess, Brian C.

    2011-01-01

    A total synthesis of (±)- hibiscone C, one member of the furanosteroid family of natural products that also includes viridin and wortmannin, is reported. Two new pathways for formation of the key diacyl furan subunit are described.

  18. US-Total Electron Content Product (USTEC)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The US Total Electron Content (US-TEC) product is designed to specify TEC over the Continental US (CONUS) in near real-time. The product uses a Kalman Filter data...

  19. Total Hip Replacement (Arthroplasty) (Beyond the Basics)

    Science.gov (United States)

    ... stiffening caused by extra bone formation, also called heterotopic ossification, is a process in which some soft ... replacement (prosthetic) parts, with the goal of relieving pain and improving function. ● Most patients require total hip ...

  20. NESDIS Blended Total Precipitable Water (TPW) Products

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The blended Total Precipitable Water (TPW) product is derived from multiple sensors/satellites. The Percentage of TPW normal (PCT), or TPW anomaly, shows the...

  1. Total renewable energy self-sufficiency strategy

    International Nuclear Information System (INIS)

    To meet required electrical power and transportation fuel, a total renewable energy self-sufficiency strategy needs to be envisaged that will not add to the degradation of our environment. (author). 6 refs., 2 tabs

  2. The total plasmatic estriol on normal gestation

    International Nuclear Information System (INIS)

    The total plasmatic estriol in normal pregnants was determinated by radioimmunological method using estriol labelled with sup(125)I. The obtained results presented similar results in comparison with methods using sup(19)C and sup(3)H. (author)

  3. TOTAL REWARDS MODEL IN ROMANIAN COMPANIES

    Directory of Open Access Journals (Sweden)

    Elena-Sabina HODOR

    2014-04-01

    Full Text Available Total Rewards Management is a subject of major importance for companies, because, by using models for this, firms can achieve their objectives of high performance. In order to analyse a validated total rewards model in Romanian Accounting and Consulting Companies, it is used The WorldatWork Total Rewards Model, which depict what contributes to applicant attraction and employee motivation and retention. Thus, the methodology of the previous survey is adjusted to the local context. The conclusions for the methodological aspects illustrate that the present research involves three strategic steps in order to achieve the objectives presented: the analysis of organizational environment of the companies from the sample, checking if Total Rewards Model proposed in the previous research is applicable for the same romanian companies from the previous survey, the analysing of the differences between results, and, if necessary, the adaptation of the model for Romania.

  4. The First Total Synthesis of Isoliquiritin

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A first total synthesis of isoliquiritin was accomplished starting from p-hydroxy- benzaldehyde and 2,4-dihydroxyacetylphenone. The key step is condensation reaction. In synthetic process need not protect the hydroxy group of reacting substance.

  5. ROE Total Nitrogen Deposition 1989-1991

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset identifies the amount of wet, dry, and total deposition of nitrogen in kilograms per hectare from 1989 to 1991 at a set of point locations across the...

  6. Total lymphoid irradiation in alloimmunity and autoimmunity

    Energy Technology Data Exchange (ETDEWEB)

    Strober, S.

    1987-12-01

    Total lymphoid irradiation has been used as an immunosuppressive regimen in autoimmune disease and organ transplantation. The rationale for its use originated from studies of patients with Hodgkin disease, in whom this radiotherapy regimen was noted to induce profound and long-lasting immune suppression and yet was well tolerated, with few long-term side effects. Total lymphoid irradiation is a unique immunosuppressive regimen that produces a selective (and long-lasting) reduction in the number and function of helper T cells and certain subsets of B cells. Conventional immunosuppressive drugs show little selectivity, and their effects are short-lived. The most important aspect of total lymphoid irradiation is the potential for achieving transplantation tolerance and permanent remissions in autoimmune disease in laboratory animals. Attempts are being made to achieve similar goals in humans given total lymphoid irradiation, so that immunosuppressive drugs can be ultimately withdrawn from transplant recipients and patients with lupus nephritis. 28 references.

  7. ROE Total Nitrogen Deposition 2011-2013

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset identifies the amount of wet, dry, and total deposition of nitrogen in kilograms per hectare from 2011 to 2013 at a set of point locations across the...

  8. ROE Total Sulfur Deposition 1989-1991

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset identifies the amount of wet, dry, and total deposition of sulfur in kilograms per hectare from 1989 to 1991 at a set of point locations across the...

  9. A scheme for total quantum teleportation

    OpenAIRE

    DelRe, E.; Crosignani, B.; Di Porto, P.

    1999-01-01

    We address the issue of totally teleporting the quantum state of an external particle, as opposed to studies on partial teleportation of external single-particle states, total teleportation of coherent states and encoded single-particle states, and intramolecular teleportation of nuclear spin states. We find a set of commuting observables whose measurement directly projects onto the Bell-basis and discuss a possible experiment, based on two-photon absorption, allowing, for the first time, tot...

  10. A strategic zone for Total's future

    International Nuclear Information System (INIS)

    In 1997, the Total company investments in the Middle East reached 1.2 billions of French Francs. This region is considered as a major growth zone by the French group. This paper summarizes the Total's participations in oil and gas activities and partnerships of Middle East countries (Abu Dhabi, Dubai, Oman, Qatar, Yemen): exploration, production, development, contracts, permits, technical assistance etc.. (J.S.)

  11. Postoperative Autologous Reinfusion in Total Knee Replacement

    OpenAIRE

    A. Crescibene; Martire, F.; Gigliotti, P.; Rende, A.; Candela, M

    2015-01-01

    Surgeries for total knee replacement (TKR) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy. Autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and the clinical efficacy. An observational retrospective study has been conducted on 124 patients, undergoing cemented total knee prosthesis replacement. Observed population was stratified into two g...

  12. The Error in Total Error Reduction

    OpenAIRE

    Witnauer, James E.; Urcelay, Gonzalo P.; Miller, Ralph R.

    2013-01-01

    Most models of human and animal learning assume that learning is proportional to the discrepancy between a delivered outcome and the outcome predicted by all cues present during that trial (i.e., total error across a stimulus compound). This total error reduction (TER) view has been implemented in connectionist and artificial neural network models to describe the conditions under which weights between units change. Electrophysiological work has revealed that the activity of dopamine neurons i...

  13. Total Quality Service and the Business College

    OpenAIRE

    James Perotti

    1995-01-01

    Moving a business college to commit to a total quality service approach is much more difficult than the literature suggests. The commitment to customer satisfaction is the essential focus of total quality service. It is unlikely to occur in business colleges. While small incremental change is readily possible, the values and culture of the faculty and administration prevent the requisite acceptance by the faculty of students as their customers, and acceptance of the faculty as customers of th...

  14. Severe Heterotopic Ossification following Total Knee Replacement

    OpenAIRE

    Dodds, Alexander L.; Keene, Gregory C. R.

    2014-01-01

    Although the incidence of minor heterotopic ossification is probably higher than what is usually expected, severe heterotopic ossification (HO) is an extremely rare event following total knee replacement surgery. We present the case of a 66-year-old woman who initially had achieved an excellent range of motion following bilateral uncemented rotating platform total knee replacement, before presenting with pain and loss of range of motion at 2 months after surgery. Severe HO was diagnosed on X-...

  15. Photoproduction total cross section and shower development

    Science.gov (United States)

    Cornet, F.; García Canal, C. A.; Grau, A.; Pancheri, G.; Sciutto, S. J.

    2015-12-01

    The total photoproduction cross section at ultrahigh energies is obtained using a model based on QCD minijets and soft-gluon resummation and the ansatz that infrared gluons limit the rise of total cross sections. This cross section is introduced into the Monte Carlo system AIRES to simulate extended air showers initiated by cosmic ray photons. The impact of the new photoproduction cross section on common shower observables, especially those related to muon production, is compared with previous results.

  16. Photoproduction total cross section and shower development

    CERN Document Server

    Cornet, F; Grau, A; Pancheri, G; Sciutto, S J

    2015-01-01

    The total photoproduction cross section at ultra-high energies is obtained using a model based on QCD minijets and soft-gluon resummation and the ansatz that infrared gluons limit the rise of total cross sections. This cross section is introduced into the Monte Carlo system AIRES to simulate extended air-showers initiated by cosmic ray photons. The impact of the new photoproduction cross section on common shower observables, especially those related to muon production, is compared with previous results.

  17. Analysis and Accounting of Total Cash Flow

    OpenAIRE

    MELANIA ELENA MICULEAC

    2012-01-01

    In order to reach the objective of supplying some relevant information regarding the liquidity inflows and outflows during a financial exercise, the total cash flow analysis must include the analysis of result cashable from operation, of payments and receipts related to the investment and of financing decisions of the last exercise, as well as the analysis of treasury variation (of cash items). The management of total cash flows ensures the correlation of current liquidness flows as consequen...

  18. Effects of xenobiotics on total antioxidant capacity

    OpenAIRE

    Ferrari, Carlos Kusano Bucalen

    2012-01-01

    The objective of this article was to review the effects of xenobiotics on total antioxidant capacity (TAC). Measurement of TAC is appropriate for evaluation of the total antioxidant defenses of blood, cells, and different kinds of tissues and organs. TAC is reduced by alcoholism, smoking, and exposure to radiation, herbicides, carbon monoxide, carbon tetrachloride, lead, arsenic, mercury, cadmium, aluminum, and other toxic elements. The test is also an important tool in evaluating environment...

  19. Total Ownership Cost -- Tools and Discipline

    OpenAIRE

    Boudreau, Mike; Naegle, Brad

    2011-01-01

    Sponsored Report (for Acquisition Research Program) Control of total ownership cost (TOC) is a continuing initiative to manage costs over the entire life cycle of a weapon system. There are several major categories of costs that contribute to Total Ownership Cost but the principal categories are (1) R&D, (2) Production, (3) Operating and Support, and (4) Disposal. System TOC is the same as Life Cycle Cost (LCC) and must be planned and controlled from requirements definition, system develop...

  20. Management of complications after total shoulder arthroplasty

    OpenAIRE

    Josef K Eichinger; Galvin, Joseph W.

    2015-01-01

    The outcomes of total shoulder arthroplasty (TSA) for painful arthritis of the glenohumeral joint are excellent with significant improvement in pain and function. Increased use of total shoulder arthroplasty over the past decade has led to identification of common complications. Although the complication rate is low, accurate and timely diagnosis, appropriate management, and implementation of methods for prevention are critical to a successful long-term outcome. The most common complications ...

  1. Discrete Total Variation: New Definition and Minimization

    OpenAIRE

    Condat, Laurent

    2016-01-01

    We propose a new definition for the gradient field of a discrete image, defined on a twice finer grid. The differentiation process from the image to its gradient field is viewed as the inverse operation of linear integration, and the proposed mapping is nonlinear. Then, we define the total variation of an image as the l1 norm of its gradient field amplitude. This new definition of the total variation yields sharp edges and has better isotropy than the classical definition.

  2. The Challenge of Total Factor Productivity

    OpenAIRE

    Erwin Diewert

    2000-01-01

    In this article, as part of the symposium on total factor productivity, Erwin Diewert of the University of British Columbia provides a comprehensive discussion of what is needed to develop reliable measures of total factor productivity in terms of output and the different classes of inputs. He concludes that the current system of industry statistics in all advanced countries has not kept up with the evolution of the economy from primary and manufacturing production to the production of servic...

  3. The International Double Taxation – Avoiding Methods

    Directory of Open Access Journals (Sweden)

    Nicoleta Barbuta-Misu

    2009-06-01

    Full Text Available The paper presents the main causes that determine double taxation, its forms, i.e. the economicdouble taxation and the international legal double taxation, the need for eliminating the double taxation andavoiding methods. In the presentation of the avoidance methods have been used practical examples forcomparison of the tax advantages for income beneficiary between: the total exemption method andprogressive exemption method, on the one hand, and total crediting method and ordinary crediting method,on the other hand, but the comparing of tax reduction between methods of exemption and crediting.

  4. Brauer-Thrall for totally reflexive modules

    CERN Document Server

    Christensen, Lars Winther; Rahmati, Hamidreza; Striuli, Janet; Wiegand, Roger

    2010-01-01

    Let R be a commutative noetherian local ring that is not Gorenstein. It was recently discovered that the category of totally reflexive modules over R is representation infinite, provided that it contains a non-free module. The main goal of this paper is to understand how complex the category of totally reflexive modules can be in this situation. Local rings (R,m) with m^3=0 are commonly regarded as the structurally simplest rings to admit diverse categorical and homological characteristics. For such rings we obtain conclusive results about the category of totally reflexive modules, modeled on the Brauer-Thrall conjectures. Starting from a non-free cyclic totally reflexive module, we construct a family of indecomposable totally reflexive R-modules that contains, for every n in N, a module that is minimally generated by n elements. Moreover, if the residue field R/m is algebraically closed, then we construct for every n in N an infinite family of indecomposable and pairwise non-isomorphic totally reflexive R-mo...

  5. Total lymphoid irradiation and discordant cardiac xenografts

    International Nuclear Information System (INIS)

    Total lymphoid irradiation can prolong concordant cardiac xenografts. The effects of total lymphoid irradiation in a discordant xenograft model (guinea pig to rat) were studied with and without adjuvant pharmacologic immunosuppression. Inbred Lewis rats were randomly allocated to one of four groups. Group 1 (n = 6) served as a control group and rats received no immunosuppression. Group 2 (n = 5) received triple-drug therapy that consisted of intraperitoneal azathioprine (2 mg/kg), cyclosporine (20 mg/kg), and methylprednisolone (1 mg/kg) for 1 week before transplantation. Group 3 animals (n = 5) received 15 Gy of total lymphoid irradiation in 12 divided doses over a 3-week period. Group 4 (n = 6) received both triple-drug therapy and total lymphoid irradiation as described for groups 2 and 3. Complement-dependent cytotoxicity assay was performed to determine if a correlation between complement-dependent cytotoxicity and rejection-free interval existed. Rejection was defined as cessation of graft pulsation and was confirmed by histologic test results. Only groups 1 and 2 showed a difference in survival (group 1, 6.9 +/- 1.0 minutes; group 2, 14.2 +/- 2.7 minutes, p = 0.02). Although total lymphoid irradiation did decrease complement-dependent cytotoxicity, linear regression revealed no correlation between complement-dependent cytotoxicity and graft survival (coefficient of correlation, 0.30). Unlike concordant cardiac xenografts, total lymphoid irradiation with or without triple-drug therapy does not prolong graft survival

  6. Total lymphoid irradiation and discordant cardiac xenografts

    Energy Technology Data Exchange (ETDEWEB)

    Kaplan, E.; Dresdale, A.R.; Diehl, J.T.; Katzen, N.A.; Aronovitz, M.J.; Konstam, M.A.; Payne, D.D.; Cleveland, R.J. (Tufts Univ. School of Medicine, Boston, MA (USA))

    1990-01-01

    Total lymphoid irradiation can prolong concordant cardiac xenografts. The effects of total lymphoid irradiation in a discordant xenograft model (guinea pig to rat) were studied with and without adjuvant pharmacologic immunosuppression. Inbred Lewis rats were randomly allocated to one of four groups. Group 1 (n = 6) served as a control group and rats received no immunosuppression. Group 2 (n = 5) received triple-drug therapy that consisted of intraperitoneal azathioprine (2 mg/kg), cyclosporine (20 mg/kg), and methylprednisolone (1 mg/kg) for 1 week before transplantation. Group 3 animals (n = 5) received 15 Gy of total lymphoid irradiation in 12 divided doses over a 3-week period. Group 4 (n = 6) received both triple-drug therapy and total lymphoid irradiation as described for groups 2 and 3. Complement-dependent cytotoxicity assay was performed to determine if a correlation between complement-dependent cytotoxicity and rejection-free interval existed. Rejection was defined as cessation of graft pulsation and was confirmed by histologic test results. Only groups 1 and 2 showed a difference in survival (group 1, 6.9 +/- 1.0 minutes; group 2, 14.2 +/- 2.7 minutes, p = 0.02). Although total lymphoid irradiation did decrease complement-dependent cytotoxicity, linear regression revealed no correlation between complement-dependent cytotoxicity and graft survival (coefficient of correlation, 0.30). Unlike concordant cardiac xenografts, total lymphoid irradiation with or without triple-drug therapy does not prolong graft survival.

  7. IAEA International Missions in Lithuania

    International Nuclear Information System (INIS)

    Description of international missions during the period of 1999-2001 is presented. At that period three IAEA international missions took place: Mission of International Physical Protection Advisor Service in 1999, Mission of International Probabilistic Safety Assessment Review Team in 2000 and Mission of International Regulatory Review Team in 2001. Topics addressed during the missions are presented

  8. THE EXISTING BARRIERS IN IMPLEMENTING TOTAL QUALITY MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Salagean Horatiu Catalin

    2014-07-01

    Full Text Available In the current market economy, companies are constantly struggling to achieve a sustained competitive advantage that will enable them to improve performance, which results in increased competitiveness, and of course, profit. Among the few competitive advantages that can become sustainable competitive advantages, quality plays a crucial role. Recent research shows that about 90% of buyers in the international market, consider quality as having at least equal importance with price in making the decision to purchase. In the opinion of some specialists in economic theory and practice, total quality refers to the holistic approach of quality, which actually means, addressing all aspects of economic and social development and technical of quality. Thus, the holistic approach of quality at organisation-wide involves procedural approach of quality, in this respect, the study focuses on this type of quality approach, i.e. the procedural approach, taking into account the strategic aspects of the continuous improvement of quality, which means in fact, the quality management. Total Quality Management is seen as a way to transform the economies of some countries to be more competitive than others. However, Total Quality Management brings not and will not produce results overnight, it is not a panacea for all the problems facing the organization. Total Quality Management requires a change in organizational culture, which must focus on meeting customer expectations and increasing the involvement of all employees to meet this objective, as an expression of the ethics of continuous improvement. In general, research on quality aiming identify why an organization should adopt the principles of total quality management, but attempts to identify the failing companies' attempts to implement total quality management principles are not so visible. Concerns companies to introduce quality management systems are becoming more pronounced, therefore, in this study we try to

  9. Effects of Human Capital and Trade Orientation on Output and Total Factor Productivity in Pakistan

    OpenAIRE

    Liaqat Ali; Muhammad Ismaeel Ramay

    2014-01-01

    The objectives of this paper were to study effects of human capital and international trade orientation on the output and total factor productivity in Pakistan. The output and Total factor productivity have been estimated using Cobb-Douglas Production function linking per worker output, per worker capital as well as labor force including and excluding the human capital stock for the period of more than five decades from 1961 to 2013. The data was taken from various secondary sources including...

  10. The total real capital structure analysis in the profits mass relevant for turnover

    OpenAIRE

    CONSTANTIN CĂRUNTU; LOREDANA MIHAELA LĂPĂDUŞI

    2009-01-01

    The mechanism operator of total actual capital on profit afferent turnover in the synthesizer manner is an important tool in assessing the economic and financial performance of the company both internally and in the diagnostic tests performed outside. Addressed the overall level of business, real capital - fixed and circulating - appears as part of operating capital; with all other forms of total capital operated in the frame of business activity, actual capital is involved in a specific circ...

  11. International Law and International Relations: Norm and reality or viceversa

    OpenAIRE

    Fred Grunfeld

    2011-01-01

    The fields of Public International Law (PIL) and International Relations (IR) share the same research area: international politics.This article focuses on the differences between social scientists (especially political scientists studying International Relations) and legal researchers (specifically in the fields of Public International Law and human rights) in terms of research methods. The focus on methodology will highlight the difference between the researchers of Public International Law ...

  12. Planning and organizing the International Week for international students

    OpenAIRE

    Johansson, Milja

    2013-01-01

    The subject of this thesis was to plan and organize an international event for students in Deggendorf Institute of Technology. The event was made for the International Office and it was implemented together with the staff of the International Office and voluntary international students. The International Week is implemented by the International Office twice a year, in winter and summer semesters. Each year the event is assumed to be a bit different and offer variable and interesting cultural ...

  13. THE CAPACITY OF INTERNATIONAL ORGANIZATIONS TO BEAR INTERNATIONAL RESPONSIBILITY

    OpenAIRE

    Ovidiu-Emilian IVANESCU

    2015-01-01

    The status of international personality is not exclusively reserved for states. In modern days, the international organizations have legal international personality and also have the capacity to be internationally responsible for their conduct. Some particularities of the legal personality of international organizations are decisive in determining their international responsibility. The study will establish the connection between the foundations of the personality and responsibility of an int...

  14. International organizations as subjects of international private law

    OpenAIRE

    Чевичалова, Ж. В.

    2016-01-01

    An integral part of the international legal functioning of international organizations is their participation in civil and economic relations. Participation of international organizations, both intergovernmental and non-governmental, in international relations of powerless character has a certain specificity and raises a number of theoretical and practical issues. An international organization in such relations is a foreign element, the presence of which qualifies relations as international p...

  15. 38 CFR 3.340 - Total and permanent total ratings and unemployability.

    Science.gov (United States)

    2010-07-01

    ... impairment of mind or body which is sufficient to render it impossible for the average person to follow a... Evaluations; Service Connection § 3.340 Total and permanent total ratings and unemployability. (a)...

  16. THE CAPACITY OF INTERNATIONAL ORGANIZATIONS TO BEAR INTERNATIONAL RESPONSIBILITY

    Directory of Open Access Journals (Sweden)

    Ovidiu-Emilian IVANESCU

    2015-07-01

    Full Text Available The status of international personality is not exclusively reserved for states. In modern days, the international organizations have legal international personality and also have the capacity to be internationally responsible for their conduct. Some particularities of the legal personality of international organizations are decisive in determining their international responsibility. The study will establish the connection between the foundations of the personality and responsibility of an international organization. It will be also analysed the situation of third parties in establishing the responsibility of an international organization.

  17. [International project--MGTX study].

    Science.gov (United States)

    Yoshikawa, Hiroaki

    2007-11-01

    MGTX Study is a multi-center, international, single-blinded, randomized trial to determine whether extended transsternal thymectomy (ETTX) for patients with myasthenia gravis receiving the prednisone protocol confers added benefits to the prednisone protocol alone. The aims of the study are answering following three questions. 1) Does ETTX combined with prednisone result in a greater improvement in myasthenic weakness, compared to prednisone alone? 2) Does ETTX combined with prednisone result in a lower total dose of prednisone, thus decreasing the likelihood of concurrent and long-term toxic effects, compared to prednisone alone? 3) Does ETTX combined with prednisone enhance quality of life by reducing adverse events and symptoms associated with the therapies, compared to prednisone alone? Primary outcome measure is consists with 1) Comparison of the prednisone protocol alone to prednisone protocol plus ETTX, based on the clinical response to therapy measured over the 3 year trial period by the Area Under the Quantitative Myasthenia Gravis (QMG) Weakness Score (AUQMG), and 2) Testing the difference in the total prednisone used over the 3 year trial period measured by pill count from blister packs (Area Under the Prednisone Dose Time Curve, AUDTC), conditional on the results of comparing AUQMG. PMID:18210825

  18. International Energy Market

    International Nuclear Information System (INIS)

    The paper analyzes recent market trends in the oil and natural gas sector. For the latter, a focus on the European gas market is then presented, whose consumption has grown considerably in these last ten years. As for the oil sector this paper investigates the key elements that have shaped its market in these years. As for oil consumption, we show that in these last 15 years China, India and the Middle East are the main responsible for the increase in World consumption. On the other hand, European OECD Countries have consistently reduced (almost 9%) their oil demand. This is due both to the dematerialization of their economy and their significant improvements in energy efficiency. As for energy intensity, in fact, Europe by far is the most efficient region in the World. On the other hand, OPEC has drastically raised its share of total production: at present the cartel accounts for more than 40% of overall production. OPEC members were the only producers to meet World's needs as oil demand expanded. The difficulties of other producers to keep up with the demand originated in the nineties, when no investment in new production capacity was brought about due to low oil prices. In the end of 2008, anyway, recession has eased the situation: for the first time in fifteen years, demand has not grown, compared to 2007 consumption. Recession has also shrunk prices, which, as soon as the demand started decreasing, have collapsed by almost 70%. As for the gas sector, the paper focuses on the European market where, after ten years from the beginning of the liberalization process, competition is still missing. In particular, the paper discusses whether LNG can bring about the competition so desperately needed. Unlike investments in pipelines, those in the LNG chain present a much lower degree of specificity, since the importer is not physically tied with the producer; moreover, it is getting increasingly common that part of the plant capacity is made available for spot

  19. Toward cleaner, quieter skies: An international debate

    Energy Technology Data Exchange (ETDEWEB)

    Aylesworth, H. Jr.

    1997-12-31

    The paper summarizes infrastructure and technology changes in the aerospace industry aimed at reducing fuel consumption and nitrous oxide emissions. Growth of total air traffic is predicted over the next 20 years; however, emissions are predicted to grow less rapidly due to increased fuel efficiency and operational productivity. Engine technology leading to fuel efficiency, reduced emissions, and noise reduction is described. Regulations pertinent to these issues are outlined, and international efforts in these areas are also briefly described. 4 figs.

  20. Third international handbook of mathematics education

    CERN Document Server

    Bishop, Alan; Keitel, Christine; Kilpatrick, Jeremy; Leung, Frederick

    2013-01-01

    This entirely new Third International Handbook of Mathematics Education comprises 31 chapters which have been written by a total of 84 different authors representing 26 nations, each a recognized expert in the field.   Comprised of four sections: Social, Political and Cultural Dimensions in Mathematics Education; Mathematics Education as a Field of Study; Technology in the Mathematics Curriculum; and International Perspectives on Mathematics Education, this Third Handbook offers essential reading for all persons interested in the future of mathematics education. The authors present challenging international perspectives on the history of mathematics education, current issues, and future directions.   What makes this Handbook unique is its structure. Each section covers past, present and future aspects of mathematics education.   The first chapter in each section identifies and analyzes historical antecedents The “middle” chapters draw attention to present-day key issues and themes The final chapter in ...