Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
Directory of Open Access Journals (Sweden)
Chi-Tang Tu
Full Text Available BACKGROUND: Although the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1 has been reported, its function in neural crest development is unclear. METHODS/PRINCIPAL FINDINGS: We found that knockdown of Arl6ip1 caused defective embryonic neural crest derivatives that were particularly severe in craniofacial cartilages. Expressions of the ectodermal patterning factors msxb, dlx3b, and pax3 were normal, but the expressions of the neural crest specifier genes foxd3, snai1b, and sox10 were greatly reduced. These findings suggest that arl6ip1 is essential for specification of neural crest derivatives, but not neural crest induction. Furthermore, we revealed that the streams of crestin- and sox10-expressing neural crest cells, which migrate ventrally from neural tube into trunk, were disrupted in arl6ip1 morphants. This migration defect was not only in the trunk neural crest, but also in the enteric tract where the vagal-derived neural crest cells failed to populate the enteric nervous system. We found that this migration defect was induced by dampened Shh signaling, which may have resulted from defective cilia. These data further suggested that arl6ip1 is required for neural crest migration. Finally, by double-staining of TUNEL and crestin, we confirmed that the loss of neural crest cells could not be attributed to apoptosis. CONCLUSIONS/SIGNIFICANCE: Therefore, we concluded that arl6ip1 is required for neural crest migration and sublineage specification.
Genetic and bibliographic information: ARL6 [GenLibi
Lifescience Database Archive (English)
Full Text Available ARL6 ADP-ribosylation factor-like 6 human Bardet-Biedl Syndrome (MeSH) Nervous Syst...Diseases (C10.228.140.617) > Bardet-Biedl Syndrome (C10.228.140.617.200) Congenital, Hereditary, and Neonata...lities, Multiple (C16.131.077) > Bardet-Biedl Syndrome (C16.131.077.112) 99A0284114 ...
Institute of Scientific and Technical Information of China (English)
GUO Qiao-Ling; GUO Jin-Chang; LI Si-Dian
2008-01-01
A density functional theory investigation on the geometries, electronic structures, and electron detachment energies of BS-, BS2-, B(BS)2- and B(BS)3- has been performed in this work. The linear ground-state structures of BS- (Ccov, 1∑+) and BS2- (D∞h, 1∑g+) prove to be similar to the previously reported BO- and BO2- with systematically lower electron detachment energies. Small boron sulfide clusters are found to favor the formation of-B=S groups which function basically as σ-radicals and dominate the ground-state structures of the systems. The perfect linear B(BS)2- (D∞h, 3∑g) and beautiful equilateral triangle B(BS)3- (D3h, 2A1") turn out to be analogous to the well-known C2v BH2 and D3h BH3, respectively. The electron affinities of BS, BS2, B(BS)2 and B(BS)3 are predicted to be 2.3, 3.69, 3.00 and 3.45 eV, respectively. The electron detachment energies calculated for BS-, BS2-, B(BS)2-, and B(BS)3- may facilitate future photoelectron spectroscopy measurements to characterize the geometrical and electronic structures of these anions.
Kathleen Zettergren
2011-01-01
A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1) The Timed up and go (TUG), 2) The Berg Balance scale (BBS), 3) Self selected gait speed, 4) Fall history, and 5) Geriatric Depression Scale (GDS). After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement), the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement), ...
KATHLEEN ZETTERGREN; JESSICA FRANCA; MICHAEL ANTUNES; CHRISTOPHER LAVALLEE
2011-01-01
A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1) The Timed up and go (TUG), 2) The Berg Balance scale (BBS), 3) Self selected gait speed, 4) Fall history, and 5) Geriatric Depression Scale (GDS). After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement), the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement), ...
Sun, Ying
2011-01-01
This article proposes an informative exploratory tool, the functional boxplot, for visualizing functional data, as well as its generalization, the enhanced functional boxplot. Based on the center outward ordering induced by band depth for functional data, the descriptive statistics of a functional boxplot are: the envelope of the 50% central region, the median curve, and the maximum non-outlying envelope. In addition, outliers can be detected in a functional boxplot by the 1.5 times the 50% central region empirical rule, analogous to the rule for classical boxplots. The construction of a functional boxplot is illustrated on a series of sea surface temperatures related to the El Niño phenomenon and its outlier detection performance is explored by simulations. As applications, the functional boxplot and enhanced functional boxplot are demonstrated on children growth data and spatio-temporal U.S. precipitation data for nine climatic regions, respectively. This article has supplementary material online. © 2011 American Statistical Association.
Markushevich, A I
1966-01-01
Entire Functions focuses on complex numbers and the algebraic operations on them and the basic principles of mathematical analysis.The book first elaborates on the concept of an entire function, including the natural generalization of the concept of a polynomial and power series. The text then takes a look at the maximum absolute value and the order of an entire function, as well as calculations for the coefficients of power series representing a given function, use of integrals, and complex numbers. The publication elaborates on the zeros of an entire function and the fundamen
DEFF Research Database (Denmark)
Campi, Stefano; Gardner, Richard; Gronchi, Paolo;
2012-01-01
Variants of the brightness function of a convex body K in n-dimensional Euclidean are investigated. The Lambertian lightness function L(K; v , w ) gives the total reflected light resulting from illumination by a light source at infinity in the direction w that is visible when looking...... in the direction v . The partial brightness function R( K ; v , w ) gives the area of the projection orthogonal to v of the portion of the surface of K that is both illuminated by a light source from the direction w and visible when looking in the direction v . A class of functions called lightness functions...... is introduced that includes L(K;.) and R(K;.) as special cases. Much of the theory of the brightness function like uniqueness, stability, and the existence and properties of convex bodies of maximal and minimal volume with finitely many function values equal to those of a given convex body, is extended...
DEFF Research Database (Denmark)
Della Pia, Eduardo Antonio; Hansen, Randi Westh; Zoonens, Manuela;
2014-01-01
Amphipols are amphipathic polymers that stabilize membrane proteins isolated from their native membrane. They have been functionalized with various chemical groups in the past years for protein labeling and protein immobilization. This large toolbox of functionalized amphipols combined...... with their interesting physico-chemical properties give opportunities to selectively add multiple functionalities to membrane proteins and to tune them according to the needs. This unique combination of properties makes them one of the most versatile strategies available today for exploiting membrane proteins onto...... surfaces for various applications in synthetic biology. This review summarizes the properties of functionalized amphipols suitable for synthetic biology approaches....
Institute of Scientific and Technical Information of China (English)
王雷
2008-01-01
<正>A power function of degree n is a function of the form f(x)=ax~n.For large n,it appears that the graph coincide with the x-axis near the origin,but it does not;the graph actually touches the x—axis only at the origin.
International Nuclear Information System (INIS)
It is a compilation of chapters written by active researchers and offer information and critical insights about semiconducting materials and devices, dielectric and ferroelectric materials, magnetic materials, composites and other functional materials. In the book, the functional materials are discussed from the mixed valences and stoichiometry points of view, to understand the structural evolution and transformation of different material systems - in particular, the role played by crystal structures in property control of functional materials using advanced characterization techniques. The book examines the properties, soft-chemistry preparations, electronic structures and crystal structures of transition and rare earth metals and their oxides. The book presents a strong argument that functional materials system is the future direction of the multidisciplinary research involving physics, chemistry, materials science and electrical engineering, with emphasis on device applications. Papers relevant to INIS are indexed separately
Hahn, M
1996-01-01
Based on empirical evidence from a free word order language (German) we propose a fundamental revision of the principles guiding the ordering of discourse entities in the forward-looking centers within the centering model. We claim that grammatical role criteria should be replaced by indicators of the functional information structure of the utterances, i.e., the distinction between context-bound and unbound discourse elements. This claim is backed up by an empirical evaluation of functional centering.
DEFF Research Database (Denmark)
Danvy, Olivier
1998-01-01
A string-formatting function such as printf in C seemingly requires dependent types, because its control string determines the rest of its arguments. We show how changing the representation of the control string makes it possible to program printf in ML (which does not allow dependent types......). The result is well typed and perceptibly more efficient than the corresponding library functions in Standard ML of New Jersey and in Caml....
DEFF Research Database (Denmark)
Danvy, Olivier
2000-01-01
A string-formatting function such as printf in C seemingly requires dependent types, because its control string determines the rest of its arguments. Examples: formula here We show how changing the representation of the control string makes it possible to program printf in ML (which does not allow...... dependent types). The result is well typed and perceptibly more efficient than the corresponding library functions in Standard ML of New Jersey and in Caml....
Nambudiripad, K B M
2014-01-01
After presenting the theory in engineers' language without the unfriendly abstraction of pure mathematics, several illustrative examples are discussed in great detail to see how the various functions of the Bessel family enter into the solution of technically important problems. Axisymmetric vibrations of a circular membrane, oscillations of a uniform chain, heat transfer in circular fins, buckling of columns of varying cross-section, vibrations of a circular plate and current density in a conductor of circular cross-section are considered. The problems are formulated purely from physical considerations (using, for example, Newton's law of motion, Fourier's law of heat conduction electromagnetic field equations, etc.) Infinite series expansions, recurrence relations, manipulation of expressions involving Bessel functions, orthogonality and expansion in Fourier-Bessel series are also covered in some detail. Some important topics such as asymptotic expansions, generating function and Sturm-Lioville theory are r...
Institute of Scientific and Technical Information of China (English)
王雷
2008-01-01
<正>Polynomial functions are among the sim- plest expressions in algebra.They are easy to evaluate:only addition and repeated multipli- cation are required.Because of this,they are often used to approximate other more compli-
Institute of Scientific and Technical Information of China (English)
K.H.DTZ
2007-01-01
1 Results The lecture will address aspects of functional organometallics related to the development of novel organometallic materials.In chromium complexes of fused arenes-regio-and diastereoselectively accessible by chromium-templated benzannulation of arylcarbenes by alkynes[1]-a haptotropic migration of the chromium fragment along the π-face of fused arenes is controlled by both thermodynamics and the substitution pattern of the arene and the metal coligand sphere,and can be applied towards an organo...
Brun, Rita; Kuo, Braden
2010-05-01
Dyspepsia is a common term used for a heterogeneous group of abdominal symptoms. Functional dyspepsia (FD) is the focus of this review. The 2006 Rome III criteria defined FD and its subgroups, postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). FD is a very common condition with a high prevalence throughout the world, adversely affecting the quality of life of patients. The pathophysiology of FD has been under investigation during the past two decades. Multiple mechanisms such as abnormal gastric emptying, visceral hypersensitivity, impaired gastric accommodation, and central nervous system factors are likely involved. Several tests are available for the assessment of various physiologic functions possibly involved in the pathogenesis of FD, and some of these could be used in clinical practice, helping to understand the abnormalities underlining patients' complaints. Currently, the possibilities of pharmacological therapy for FD are still limited, however, experience of using prokinetics, tricyclic antidepressants, selective serotonin-reuptake inhibitors (SSRIs), proton-pump inhibitors (PPIs), and several alternative techniques has been accumulated. The different combinations of alterations in physiologic gastrointestinal and central nervous system functions result in the very heterogeneous nature of FD so combined approaches to these patients could be beneficial in challenging cases. PMID:21180597
Institute of Scientific and Technical Information of China (English)
2005-01-01
2005200 The effect of body position changes on lung function, lung CT imaging and pathology in an oleic acid induced acute lung injury model. JI Xin-ping (戢新平), et al. Dept Emergency, 1st Affili Hosp, China Med Univ, Shenyang 110001. Chin J Tuberc Respir Dis, 2005;28(1) :33-36. Objective: To study the effect of body position changes on lung mechanics, oxygenation, CT images and pathology in an oleic acid-induced acute lung injury (ALl) model. Methods: The study groups con-
Is functional behavioral assessment functional?
2006-01-01
Abstract Traditional methods of discipline, like punishment, suspension, and expulsion have in the past seemed beneficial, on a short-term basis, against problem behavior in schools. Four schools in Norway have recently implemented Functional Behavior Assessment (FBA) as part of a pilot project, to test the School-Wide Positive Behavioral Support (SW-PBS). A completed FBA procedure reveals the setting events, the antecedents and the consequences around the problem behavior, which provides ...
International Nuclear Information System (INIS)
The term lung function is often restricted to the assessment of volume time curves measured at the mouth. Spirometry includes the assessment of lung volumes which can be mobilised with the corresponding flow-volume curves. In addition, lung volumes that can not be mobilised, such as the residual volume, or only partially as FRC and TLC can be measured by body plethysmography combined with the determination of the airway resistance. Body plethysmography allows the correct positioning of forced breathing manoeuvres on the volume-axis, e.g. before and after pharmacotherapy. Adding the CO single breath transfer factor (TLCO), which includes the measurement of the ventilated lung volume using He, enables a clear diagnosis of different obstructive, restrictive or mixed ventilatory defects with and without trapped air. Tests of reversibility and provocation, as well as the assessment of inspiratory mouth pressures (PImax, P0.1) help to classify the underlying disorder and to clarify treatment strategies. For further information and to complete the diagnostic of disturbances of the ventilation, diffusion and/or perfusion (capillar-)arterial bloodgases at rest and under physical strain sometimes amended by ergospirometry are recommended. Ideally, lung function measurements are amended by radiological and nuclear medicine techniques. (orig.)
Directory of Open Access Journals (Sweden)
Kathleen Zettergren
2011-11-01
Full Text Available A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1 The Timed up and go (TUG, 2 The Berg Balance scale (BBS, 3 Self selected gait speed, 4 Fall history, and 5 Geriatric Depression Scale (GDS. After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement, the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement, gait speed increased from .26 m/s to .37 m/s (42% improvement and GDS scores remained unchanged. The Nintendo Wii Fit may be a viable alternative to independent exercise programs for people diagnosed with idiopathic PD.
Directory of Open Access Journals (Sweden)
KATHLEEN ZETTERGREN
2011-11-01
Full Text Available A 69 year old male with idiopathic Parkinson’s disease participated in a 60-minute, bi-weekly training program using the Nintendo Wii fit gaming system. Pre-test/post-test assessments included: 1 The Timed up and go (TUG, 2 The Berg Balance scale (BBS, 3 Self selected gait speed, 4 Fall history, and 5 Geriatric Depression Scale (GDS. After 8 weeks, the subject’s BBS score increased from 31 to 42 (35% improvement, the TUG decreased from 36.5 seconds to 24.1 seconds (34% improvement, gait speed increased from .26 m/s to .37 m/s (42% improvement and GDS scores remained unchanged. The Nintendo Wii Fit may be a viable alternative to independent exercise programs for people diagnosed with idiopathic PD
Asadchy, V S; Vehmas, J; Tretyakov, S A
2014-01-01
Conventional mirrors obey Snell's reflection law: a plane wave is reflected as a plane wave, at the same angle. To engineer spatial distributions of fields reflected from a mirror, one can either shape the reflector (for example, creating a parabolic reflector) or position some phase-correcting elements on top of a mirror surface (for example, designing a reflectarray antenna). Here we show, both theoretically and experimentally, that full-power reflection with general control over reflected wave phase is possible with a single-layer array of deeply sub-wavelength inclusions. These proposed artificial surfaces, metamirrors, provide various functions of shaped or nonuniform reflectors without utilizing any mirror. This can be achieved only if the forward and backward scattering of the inclusions in the array can be engineered independently, and we prove that it is possible using electrically and magnetically polarizable inclusions. The proposed sub-wavelength inclusions possess desired reflecting properties at...
Energy Technology Data Exchange (ETDEWEB)
Lee, S. R.; Park, S. K.; Kim, J. J. [Hanyang University College of Medicine, Seoul (Korea, Republic of); Jeon, H. J.; Jeon, H. S.; Kim, D. Y. [Gang Nam Hospital, Seoul (Korea, Republic of)
1984-09-15
Morphologic changes of spinal canal and dural sac during spinal movement (flexion-extension) were analysed and reported with the base of cross sectional anatomy, as early as 1942. After that, this movement was emphasized and used in myelography in many countries under the name of functional myelography, for accurate diagnosis of spinal stenosis as herniated disc, but nor used commonly in Korea. Authors analysed functional myelographic findings of 78 cases, 37 of normal and 41 of surgically confirmed herniated disc, to intend to confirm the necessity of spinal movement during myelography. The results were as follows; 1. In normal group, anterior border of dural sac is stright with flexion, but indented in extension at the level of intervertebral space and this indentation is less prominent at L5-S1. 2. In normal group with extension, posterior indentation of dural sac is more prominent at the level of intervertebral space than body, A-P diameter of dural sac is narrowed all the level of intervertebral space except L5-S1,and dural sac moved anteriorly (near to the posterior portion of spinal body or intervertebral space) at the level L5-S1 and all spinal body. 3. In disc patient, anterior indentation of dural sac is persist in both views (flexion and extension) and much more exaggerated with extension, but less prominent at L5-S1. 4. In herniated disc patient with extension, anterior movement of anterior dural border at the level of L5-S1 is much decreased than normal.
Relations between Lipschitz functions and convex functions
Institute of Scientific and Technical Information of China (English)
RUAN Yingbin
2005-01-01
We discuss the relationship between Lipschitz functions and convex functions.By these relations, we give a sufficient condition for the set of points where Lipschitz functions on a Hilbert space is Frechet differentiable to be residual.
Gaussian Functions, Γ-Functions and Wavelets
Institute of Scientific and Technical Information of China (English)
蔡涛; 许天周
2003-01-01
The relations between Gaussian function and Γ-function is revealed first at one-dimensional situation. Then, the Fourier transformation of n-dimensional Gaussian function is deduced by a lemma. Following the train of thought in one-dimensional situation, the relation between n-dimensional Gaussian function and Γ-function is given. By these, the possibility of arbitrary derivative of an n-dimensional Gaussian function being a mother wavelet is indicated. The result will take some enlightening role in exploring the internal relations between Gaussian function and Γ-function as well as in finding high-dimensional mother wavelets.
Differential Privacy for Functions and Functional Data
Hall, Rob; Wasserman, Larry
2012-01-01
Differential privacy is a framework for privately releasing summaries of a database. Previous work has focused mainly on methods for which the output is a finite dimensional vector, or an element of some discrete set. We develop methods for releasing functions while preserving differential privacy. Specifically, we show that adding an appropriate Gaussian process to the function of interest yields differential privacy. When the functions lie in the same RKHS as the Gaussian process, then the correct noise level is established by measuring the "sensitivity" of the function in the RKHS norm. As examples we consider kernel density estimation, kernel support vector machines, and functions in reproducing kernel Hilbert spaces.
Functionality and homogeneity.
2011-01-01
Functionality and homogeneity are two of the five Sustainable Safety principles. The functionality principle aims for roads to have but one exclusive function and distinguishes between traffic function (flow) and access function (residence). The homogeneity principle aims at differences in mass, spe
Noncommutative Bessel symmetric functions
Novelli, Jean-Christophe; Thibon, Jean-Yves
2006-01-01
The consideration of tensor products of 0-Hecke algebra modules leads to natural analogs of the Bessel J-functions in the algebra of noncommutative symmetric functions. This provides a simple explanation of various combinatorial properties of Bessel functions.
International Nuclear Information System (INIS)
This invention relates to the investigation of body function, especially small bowel function but also liver function, using bile acids and bile salts or their metabolic precursors labelled with radio isotopes and selenium or tellurium. (author)
Random functions and turbulence
Panchev, S
1971-01-01
International Series of Monographs in Natural Philosophy, Volume 32: Random Functions and Turbulence focuses on the use of random functions as mathematical methods. The manuscript first offers information on the elements of the theory of random functions. Topics include determination of statistical moments by characteristic functions; functional transformations of random variables; multidimensional random variables with spherical symmetry; and random variables and distribution functions. The book then discusses random processes and random fields, including stationarity and ergodicity of random
Gersten, A.
1999-01-01
By applying projection operators to state vectors of coordinates we obtain subspaces in which these states are no longer normalized according to Dirac's delta function but normalized according to what we call "incomplete delta functions". We show that this class of functions satisfy identities similar to those satisfied by the Dirac delta function. The incomplete delta functions may be employed advantageously in projected subspaces and in the link between functions defined on the whole space ...
Functional microorganisms for functional food quality.
Gobbetti, M; Cagno, R Di; De Angelis, M
2010-09-01
Functional microorganisms and health benefits represent a binomial with great potential for fermented functional foods. The health benefits of fermented functional foods are expressed either directly through the interactions of ingested live microorganisms with the host (probiotic effect) or indirectly as the result of the ingestion of microbial metabolites synthesized during fermentation (biogenic effect). Since the importance of high viability for probiotic effect, two major options are currently pursued for improving it--to enhance bacterial stress response and to use alternative products for incorporating probiotics (e.g., ice cream, cheeses, cereals, fruit juices, vegetables, and soy beans). Further, it seems that quorum sensing signal molecules released by probiotics may interact with human epithelial cells from intestine thus modulating several physiological functions. Under optimal processing conditions, functional microorganisms contribute to food functionality through their enzyme portfolio and the release of metabolites. Overproduction of free amino acids and vitamins are two classical examples. Besides, bioactive compounds (e.g., peptides, γ-amino butyric acid, and conjugated linoleic acid) may be released during food processing above the physiological threshold and they may exert various in vivo health benefits. Functional microorganisms are even more used in novel strategies for decreasing phenomenon of food intolerance (e.g., gluten intolerance) and allergy. By a critical approach, this review will aim at showing the potential of functional microorganisms for the quality of functional foods. PMID:20830633
Rough function model and rough membership function
Institute of Scientific and Technical Information of China (English)
Wang Yun; Guan Yanyong; Huang Zhiqin
2008-01-01
Two pairs of approximation operators, which are the scale lower and upper approximations as well as the real line lower and upper approximations, are defined. Their properties and antithesis characteristics are analyzed. The rough function model is generalized based on rough set theory, and the scheme of rough function theory is made more distinct and complete. Therefore, the transformation of the real function analysis from real line to scale is achieved. A series of basic concepts in rough function model including rough numbers, rough intervals, and rough membership functions are defined in the new scheme of the rough function model. Operating properties of rough intervals similar to rough sets are obtained. The relationship of rough inclusion and rough equality of rough intervals is defined by two kinds of tools, known as the lower (upper) approximation operator in real numbers domain and rough membership functions. Their relative properties are analyzed and proved strictly, which provides necessary theoretical foundation and technical support for the further discussion of properties and practical application of the rough function model.
Entire functions sharing one small function
Institute of Scientific and Technical Information of China (English)
LI Yun-tong; CAO Yao
2007-01-01
The uniqueness problem of entire functions sharing one small function was studied. By Picard's Theorem, we proved that for two transcendental entire functions f (z) and g(z), a positive integer n≥9, and a(z) (not identically eaqual to zero) being a common small function related to f (z) and g(z), if f n(z)(f(z)-1)f'(z) and gn(z)(g'z)-1)g'(z) share a(z) CM, where CM is counting multiplicity, then g(z)≡f (z). This is an extended version of Fang and Hong's theorem [ Fang ML, Hong W, A unicity theorem for entire functions concerning differential polynomials, Journal of Indian Pure Applied Mathematics, 2001, 32 (9): 1343-1348].
On $ \\delta $-perfect functions
C. K. Basu
2004-01-01
$ \\delta $-continuous [6] and $ \\delta $-perfect [5] functions are both introduced by T.~Noiri in the similar fashion as continuous and perfect functions. The purpose of the present paper is to investigate several properties of $ \\delta$-perfect functions and also to determine some topological properties which are preserved by $ \\delta$-continuous $ \\delta$-perfect functions.
DEFF Research Database (Denmark)
Bysted, Tommy Kristensen; Hamila, R.; Gabbouj, M.;
1998-01-01
A new correlation function called the Teager correlation function is introduced in this paper. The connection between this function, the Teager energy operator and the conventional correlation function is established. Two applications are presented. The first is the minimization of the Teager err...... norm and the second one is the use of the instantaneous Teager correlation function for simultaneous estimation of TDOA and FDOA (Time and Frequency Difference of Arrivals)....
Relations between Lipschitz functions and convex functions
Institute of Scientific and Technical Information of China (English)
无
2005-01-01
[1]Zajicek, J., On the differentation of convex functions in finite and infinite dimensional spaces, Czech J. Math.,1979, 29: 340-348.[2]Hu, T. C., Klee, V. L., Larman, D. G., Optimization of globally convex functions, SIAM J. Control Optim., 1989,27: 1026-1047.[3]Cepedello Boiso, M., Approximation of Lipschitz functions by △-convex functions in Banach spaces, Israel J.Math., 1998, 106: 269-284.[4]Asplund, E., Frechet differentiability of convex functions, Acta Math., 1968, 121: 31-47.[5]Johnson, J. A., Lipschitz spaces, Pacific J. Math, 1974, 51: 177-186.[6]Stromberg, T., The operation of infimal convolution, Dissert. Math., (Rozprawy Mat.), 1996, 325: 58.[7]Kadison, R. V., Ringrose, J. R., Fundamentals of the theory of operator algebras, volume Ⅰ: Elementary Theory,Graduate Studies in Math., vol. 15, Amer. Math. Soc., 1997.[8]Phelps, R. R., Convex functions,monotone operators and differentiability, Lect. Notes in Math., vol. 1364,Springer-Verlag, 1977.[9]Lindenstrauss, J., On operators which attain their norm, Israel J. Math., 1963, 1: 139-148.[10]Press, D., Gateaux differentiable functions are somewhere Frechet differentiable, Rend. Circ. Mat. Palermo,1984, 33: 122-133.[11]Press, D., Differentiability of Lipschitz functions on Banach spaces, J. Funct. Anal., 1990, 91:312-345.[12]Lindenstrauss, J., Press, D., On Frechet differentiability of Lipschitz maps between Banach spaces, Annals of Math., 2003, 157: 257-288.[13]Press, D., Gateaux differentiable Lipschitz functions need not be Frechet differentiable on a residual set, Supplemento Rend. Circ. Mat. Palermo, Serie Ⅱ, 1982, 2: 217-222.
Generalised Elliptic Functions
England, Matthew
2011-01-01
We consider multiply periodic functions, sometimes called Abelian functions, defined with respect to the period matrices associated with classes of algebraic curves. We realise them as generalisations of the Weierstras P-function using two different approaches. These functions arise naturally as solutions to some of the important equations of mathematical physics and their differential equations, addition formulae, and applications have all been recent topics of study. The first approach discussed sees the functions defined as logarithmic derivatives of the sigma-function, a modified Riemann theta-function. We can make use of known properties of the sigma function to derive power series expansions and in turn the properties mentioned above. This approach has been extended to a wide range of non hyperelliptic and higher genus curves and an overview of recent results is given. The second approach defines the functions algebraically, after first modifying the curve into its equivariant form. This approach allows...
DEFF Research Database (Denmark)
Raket, Lars Lau
We propose a direction it the field of statistics which we will call functional object analysis. This subfields considers the analysis of functional objects defined on continuous domains. In this setting we will focus on model-based statistics, with a particularly emphasis on mixed......-effect formulations, where the observed functional signal is assumed to consist of both fixed and random functional effects. This thesis takes the initial steps toward the development of likelihood-based methodology for functional objects. We first consider analysis of functional data defined on high...
DEFF Research Database (Denmark)
Markvorsen, Steen
2007-01-01
We consider a specific function of two variables whose graph surface resembles a blue lagoon. The function has a saddle point $p$, but when the function is restricted to any given straight line through $p$ it has a {\\em{strict local minimum}} along that line at $p$.......We consider a specific function of two variables whose graph surface resembles a blue lagoon. The function has a saddle point $p$, but when the function is restricted to any given straight line through $p$ it has a {\\em{strict local minimum}} along that line at $p$....
Functionalized boron nitride nanotubes
Sainsbury, Toby; Ikuno, Takashi; Zettl, Alexander K
2014-04-22
A plasma treatment has been used to modify the surface of BNNTs. In one example, the surface of the BNNT has been modified using ammonia plasma to include amine functional groups. Amine functionalization allows BNNTs to be soluble in chloroform, which had not been possible previously. Further functionalization of amine-functionalized BNNTs with thiol-terminated organic molecules has also been demonstrated. Gold nanoparticles have been self-assembled at the surface of both amine- and thiol-functionalized boron nitride Nanotubes (BNNTs) in solution. This approach constitutes a basis for the preparation of highly functionalized BNNTs and for their utilization as nanoscale templates for assembly and integration with other nanoscale materials.
Sun, Ying
2012-08-03
This article proposes functional median polish, an extension of univariate median polish, for one-way and two-way functional analysis of variance (ANOVA). The functional median polish estimates the functional grand effect and functional main factor effects based on functional medians in an additive functional ANOVA model assuming no interaction among factors. A functional rank test is used to assess whether the functional main factor effects are significant. The robustness of the functional median polish is demonstrated by comparing its performance with the traditional functional ANOVA fitted by means under different outlier models in simulation studies. The functional median polish is illustrated on various applications in climate science, including one-way and two-way ANOVA when functional data are either curves or images. Specifically, Canadian temperature data, U. S. precipitation observations and outputs of global and regional climate models are considered, which can facilitate the research on the close link between local climate and the occurrence or severity of some diseases and other threats to human health. © 2012 International Biometric Society.
Babusci, D.; Dattoli, G.; Germano, B.; Martinelli, M. R.; Ricci, P. E.
2011-01-01
We use the operator method to evaluate a class of integrals involving Bessel or Bessel-type functions. The technique we propose is based on the formal reduction of these family of functions to Gaussians.
Lott, Steven
2015-01-01
This book is for developers who want to use Python to write programs that lean heavily on functional programming design patterns. You should be comfortable with Python programming, but no knowledge of functional programming paradigms is needed.
Functionalized diamond nanoparticles
Beaujuge, Pierre M.
2014-10-21
A diamond nanoparticle can be functionalized with a substituted dienophile under ambient conditions, and in the absence of catalysts or additional reagents. The functionalization is thought to proceed through an addition reaction.
Harmonic hypergeometric functions
Directory of Open Access Journals (Sweden)
R. A. Al-Khal
2006-09-01
Full Text Available In this paper we try to uncover some of the inequalities associating hypergeometric functions with planer harmonic mappings. Sharp coefficient relations, distortion theorems and neighborhood are given for these functions. Furthermore, convolution products are considered.
Dependence for functional data
Valencia García, Dalia Jazmín
2014-01-01
Measuring dependence is a basic question when dealing with functional observations. It is of great interest to know the effect that one or more functional variables can have on other ones, and even predict values of one variable from another. Although, in the functional context, this theory has not been as extensively studied,some techniques to measure dependence in functional data have already been implemented, providing a single value which represents the degree of relation between the sets...
Pseudolinear functions and optimization
Mishra, Shashi Kant
2015-01-01
Pseudolinear Functions and Optimization is the first book to focus exclusively on pseudolinear functions, a class of generalized convex functions. It discusses the properties, characterizations, and applications of pseudolinear functions in nonlinear optimization problems.The book describes the characterizations of solution sets of various optimization problems. It examines multiobjective pseudolinear, multiobjective fractional pseudolinear, static minmax pseudolinear, and static minmax fractional pseudolinear optimization problems and their results. The authors extend these results to locally
Parton Fragmentation Functions
Metz, Andreas
2016-01-01
The field of fragmentation functions of light quarks and gluons is reviewed. In addition to integrated fragmentation functions, attention is paid to the dependence of fragmentation functions on transverse momenta and on polarization degrees of freedom. Higher-twist and di-hadron fragmentation functions are considered as well. Moreover, the review covers both theoretical and experimental developments in single-inclusive hadron production in electron-positron annihilation, deep-inelastic lepton-nucleon scattering, and proton-proton collisions.
Chemical functionalization of graphene
Boukhvalov, D. W.; Katsnelson, M I
2008-01-01
Experimental and theoretical results on chemical functionalization of graphene are reviewed. Using hydrogenated graphene as a model system, general principles of the chemical functionalization are formulated and discussed. It is shown that, as a rule, 100% coverage of graphene by complex functional groups (in contrast with hydrogen and fluorine) is unreachable. A possible destruction of graphene nanoribbons by fluorine is considered. The functionalization of infinite graphene and graphene nan...
Montanaro, Ashley; Osborne, Tobias J.
2008-01-01
In this paper we introduce the study of quantum boolean functions, which are unitary operators f whose square is the identity: f^2 = I. We describe several generalisations of well-known results in the theory of boolean functions, including quantum property testing; a quantum version of the Goldreich-Levin algorithm for finding the large Fourier coefficients of boolean functions; and two quantum versions of a theorem of Friedgut, Kalai and Naor on the Fourier spectra of boolean functions. In o...
Phylogenetic molecular function annotation
Barbara E Engelhardt; Jordan, Michael I.; Repo, Susanna T; Brenner, Steven E
2009-01-01
It is now easier to discover thousands of protein sequences in a new microbial genome than it is to biochemically characterize the specific activity of a single protein of unknown function. The molecular functions of protein sequences have typically been predicted using homology-based computational methods, which rely on the principle that homologous proteins share a similar function. However, some protein families include groups of proteins with different molecular functions. A phylogenetic ...
Graphomania: learning function plots
Leskovšek, Gregor
2013-01-01
In the first part of our thesis Graphomania: learning function plots (hereinafter Graphomania) we present profesional applications of our current problem space and a drawing graphs of functions, manipulation of the current features: zoom in, zoom out, translate = pan add vertical poles and horizontal and oblique asymptotes in the following programs: (1) Draw Function Graphs (rechneronline.de/function-graphs/), (2) Derive (mathematical assistant for your PC, version 6.10), (3) GeoGebra 4.2 (ge...
Directory of Open Access Journals (Sweden)
Mohsen Razzaghi
2000-01-01
Full Text Available A direct method for finding the solution of variational problems using a hybrid function is discussed. The hybrid functions which consist of block-pulse functions plus Chebyshev polynomials are introduced. An operational matrix of integration and the integration of the cross product of two hybrid function vectors are presented and are utilized to reduce a variational problem to the solution of an algebraic equation. Illustrative examples are included to demonstrate the validity and applicability of the technique.
Feldman, Carol Fleisher
1977-01-01
Author advocates the view that meaning is necessarily dependent upon the communicative function of language and examines the objections, particularly those of Noam Chomsky, to this view. Argues that while Chomsky disagrees with the idea that communication is the essential function of language, he implicitly agrees that it has a function.…
Anderson, Deborah S.; Kristiansen, Connie M.
1990-01-01
Discusses the Attitude Functions Inventory (AFI), which assesses the extent to which a person's attitude fulfills each of four psychological functions. Reports findings of a study, involving 249 undergraduates, that tested the construct validity of the AFI. Suggests that the AFI provides conceptually meaningful measures of the functions of…
Bates, Elizabeth; MacWhinney, Brian
A defense of functionalism in linguistics, and more specifically the competition model of linguistic performance, examines six misconceptions about the functionalist approach. Functionalism is defined as the belief that the forms of natural languages are created, governed, constrained, acquired, and used for communicative functions. Functionalism…
Clinical functional MRI. Presurgical functional neuroimaging
Energy Technology Data Exchange (ETDEWEB)
Stippich, C. (ed.) [Heidelberg Univ. (Germany). Div. of Neuroradiology
2007-07-01
Functional magnetic resonance imaging (fMRI) permits noninvasive imaging of the ''human brain at work'' under physiological conditions. This is the first textbook on clinical fMRI. It is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery. State of the art fMRI procedures are presented, with detailed consideration of the physiological and methodological background, imaging and data processing, normal and pathological findings, diagnostic possibilities and limitations, and other related techniques. All chapters are written by recognized experts in their fields, and the book is designed to be of value to beginners, trained clinicians and experts alike. (orig.)
D'Hoker, Eric; Gurdogan, Omer; Vanhove, Pierre
2015-01-01
We consider properties of modular graph functions, which are non-holomorphic modular functions associated with the Feynman graphs for a conformal scalar field theory on a two-dimensional torus. Such functions arise, for example, in the low energy expansion of genus-one Type II superstring amplitudes. We demonstrate that these functions are sums, with rational coefficients, of special values of single-valued elliptic multiple polylogarithms, which will be introduced in this paper. This insight suggests the many interrelations between these modular graph functions (a few of which were motivated in an earlier paper) may be obtained as a consequence of identities involving elliptic polylogarithms.
The Cosmological Mass Function
Monaco, P
1997-01-01
This thesis aims to review the cosmological mass function problem, both from the theoretical and the observational point of view, and to present a new mass function theory, based on realistic approximations for the dynamics of gravitational collapse. Chapter 1 gives a general introduction on gravitational dynamics in cosmological models. Chapter 2 gives a complete review of the mass function theory. Chapters 3 and 4 present the ``dynamical'' mass function theory, based on truncated Lagrangian dynamics and on the excursion set approach. Chapter 5 reviews the observational state-of-the-art and the main applications of the mass function theories described before. Finally, Chapter 6 gives conclusions and future prospects.
DEFF Research Database (Denmark)
Rosenstand, Claus Andreas Foss; Laursen, Per Kyed
2013-01-01
How does one manage functional power relations between leading functions in vision driven digital media creation, and this from idea to master during the creation cycle? Functional power is informal, and it is understood as roles, e.g. project manager, that provide opportunities to contribute...... to the product quality. The area of interest is the vision driven digital media industry in general; however, the point of departure is the game industry due to its aesthetic complexity. The article's contribution to the area is a power graph, which shows the functional power of the leading functions according...
Hall, Joanne L; Donovan, Diane
2012-01-01
In 1980 Alltop produced a family of cubic phase sequences that nearly meet the Welch bound for maximum non-peak correlation magnitude. This family of sequences were shown by Wooters and Fields to be useful for quantum state tomography. Alltop's construction used a function that is not planar, but whose difference function is planar. In this paper we show that Alltop type functions cannot exist in fields of characteristic 3 and that for a known class of planar functions, $x^3$ is the only Alltop type function.
Transfer function combinations
Zhou, Liang
2012-10-01
Direct volume rendering has been an active area of research for over two decades. Transfer function design remains a difficult task since current methods, such as traditional 1D and 2D transfer functions, are not always effective for all data sets. Various 1D or 2D transfer function spaces have been proposed to improve classification exploiting different aspects, such as using the gradient magnitude for boundary location and statistical, occlusion, or size metrics. In this paper, we present a novel transfer function method which can provide more specificity for data classification by combining different transfer function spaces. In this work, a 2D transfer function can be combined with 1D transfer functions which improve the classification. Specifically, we use the traditional 2D scalar/gradient magnitude, 2D statistical, and 2D occlusion spectrum transfer functions and combine these with occlusion and/or size-based transfer functions to provide better specificity. We demonstrate the usefulness of the new method by comparing to the following previous techniques: 2D gradient magnitude, 2D occlusion spectrum, 2D statistical transfer functions and 2D size based transfer functions. © 2012 Elsevier Ltd.
ALGEBROIDAL FUNCTION AND ITS DERIVED FUNCTION IN UNIT CIRCULAR DISC
Institute of Scientific and Technical Information of China (English)
Huo Yingying; Sun Daochun
2009-01-01
In this article, the authors define the derived function of an algeboidal function in the unit disc, prove it is an algabriodal function, and study the order of algebroidal function and that of its derived function in unit circular disc.
Marine Functional Foods and Functional Ingredients
Hurst, D.
2006-01-01
This briefing paper gives insights into the issues surrounding marine functional foods and highlights opportunities for researchers in the marine sciences and food sciences areas to engage in collaborative research. It will be used as the basis for further consultation with the research community and firms in the marine and food sectors and to assist in exploring and prioritising research themes.
Directory of Open Access Journals (Sweden)
Jiri Patera
2008-01-01
Full Text Available We review and further develop the theory of $E$-orbit functions. They are functions on the Euclidean space $E_n$ obtained from the multivariate exponential function by symmetrization by means of an even part $W_{e}$ of a Weyl group $W$, corresponding to a Coxeter-Dynkin diagram. Properties of such functions are described. They are closely related to symmetric and antisymmetric orbit functions which are received from exponential functions by symmetrization and antisymmetrization procedure by means of a Weyl group $W$. The $E$-orbit functions, determined by integral parameters, are invariant withrespect to even part $W^{aff}_{e}$ of the affine Weyl group corresponding to $W$. The $E$-orbit functions determine a symmetrized Fourier transform, where these functions serve as a kernel of the transform. They also determine a transform on a finite set of points of the fundamental domain $F^{e}$ of the group $W^{aff}_{e}$ (the discrete $E$-orbit function transform.
Directory of Open Access Journals (Sweden)
Anatoliy Klimyk
2007-02-01
Full Text Available In the paper, properties of antisymmetric orbit functions are reviewed and further developed. Antisymmetric orbit functions on the Euclidean space $E_n$ are antisymmetrized exponential functions. Antisymmetrization is fulfilled by a Weyl group, corresponding to a Coxeter-Dynkin diagram. Properties of such functions are described. These functions are closely related to irreducible characters of a compact semisimple Lie group $G$ of rank $n$. Up to a sign, values of antisymmetric orbit functions are repeated on copies of the fundamental domain $F$ of the affine Weyl group (determined by the initial Weyl group in the entire Euclidean space $E_n$. Antisymmetric orbit functions are solutions of the corresponding Laplace equation in $E_n$, vanishing on the boundary of the fundamental domain $F$. Antisymmetric orbit functions determine a so-called antisymmetrized Fourier transform which is closely related to expansions of central functions in characters of irreducible representations of the group $G$. They also determine a transform on a finite set of points of $F$ (the discrete antisymmetric orbit function transform. Symmetric and antisymmetric multivariate exponential, sine and cosine discrete transforms are given.
Elliptic hypergeometric functions
Spiridonov, V P
2016-01-01
This is author's Habilitation Thesis (Dr. Sci. dissertation) submitted at the beginning of September 2004. It is written in Russian and is posted due to the continuing requests for the manuscript. The content: 1. Introduction, 2. Nonlinear chains with the discrete time and their self-similar solutions, 3. General theory of theta hypergeometric series, 4. Theta hypergeometric integrals, 5. Biorthogonal functions, 6. Elliptic hypergeometric functions with |q|=1, 7. Conclusion, 8. References. It contains an outline of a general heuristic scheme for building univariate special functions through self-similar reductions of spectral transformation chains, which allowed construction of the differential-difference q-Painleve equations, as well as of the most general known set of elliptic biorthogonal functions comprising all classical orthogonal polynomials and biorthogonal rational functions. One of the key results of the thesis consists in the discovery of genuinely transcendental elliptic hypergeometric functions d...
Counting with symmetric functions
Mendes, Anthony
2015-01-01
This monograph provides a self-contained introduction to symmetric functions and their use in enumerative combinatorics. It is the first book to explore many of the methods and results that the authors present. Numerous exercises are included throughout, along with full solutions, to illustrate concepts and also highlight many interesting mathematical ideas. The text begins by introducing fundamental combinatorial objects such as permutations and integer partitions, as well as generating functions. Symmetric functions are considered in the next chapter, with a unique emphasis on the combinatorics of the transition matrices between bases of symmetric functions. Chapter 3 uses this introductory material to describe how to find an assortment of generating functions for permutation statistics, and then these techniques are extended to find generating functions for a variety of objects in Chapter 4. The next two chapters present the Robinson-Schensted-Knuth algorithm and a method for proving Pólya’s enu...
Pisani, Pablo
2015-01-01
We present a pedagogical exposition of some applications of functional methods in quantum field theory: we use heat-kernel and zeta-function techniques to study the Casimir effect, the pair production in strong electric fields, quantum fields at finite temperature and beta-functions for a self-interacting scalar field, QED and pure Yang-Mills theories. The more recent application to the UV/IR mixing phenomenon in noncommutative theories is also discussed in this framework.
Directory of Open Access Journals (Sweden)
Catalin Angelo Ioan
2013-04-01
Full Text Available The paper investigates some aspects of the behavior of homogeneous functions. Afterdetermining the degree of homogeneity of partial derivatives of a homogeneousfunction, it is determined their general form in the case of integer degree ofhomogeneity and they are defined in 0. It also generalizes the Euler relationfor homogeneous functions to the higher order partial derivatives. Finally, itis determined a necessary condition for concavity of these functions.
Broker, Reinier
2010-01-01
The moduli space of principally polarized abelian surfaces is parametrized by three Igusa functions. In this article we investigate a new way to evaluate these functions by using Siegel Eisenstein series. We explain how to compute the Fourier coefficients of certain Siegel modular forms using classical modular forms of half-integral weight. One of the results in this paper is an explicit algorithm to evaluate the Igusa functions to a prescribed precision.
Functional Capacity Evaluation & Disability
Chen, Joseph J.
2007-01-01
Function, Impairment, and Disability are words in which many physicians have little interest. Most physicians are trained to deal with structure and physiology and not function and disability. The purpose of this article is to address some of the common questions that many physicians have with the use of functional capacity evaluation and disability and also to provide a unifying model that can explain the medical and societal variables in predicting disability. We will first define the funct...
DEFF Research Database (Denmark)
Rumessen, J J; Gudmand-Høyer, E
1988-01-01
Twenty-five patients with functional bowel disease were given fructose, sorbitol, fructose-sorbitol mixtures, and sucrose. The occurrence of malabsorption was evaluated by means of hydrogen breath tests and the gastrointestinal symptoms, if any, were recorded. One patient could not be evaluated...... with functional bowel disease. The findings may have direct influence on the dietary guidance given to a major group of patients with functional bowel disease and may make it possible to define separate entities in this disease complex....
DEFF Research Database (Denmark)
Lind, Morten
2011-01-01
Multilevel Flow Modeling (MFM) has been proposed as a tool for representing goals and functions of complex industrial plants and suggested as a basis for reasoning about control situations. Lind presents an introduction to MFM but do not describe how control functions are used in the modeling....... The purpose of the present paper is to serve as a companion paper to this introduction by explaining the basic principles used in MFM for representation of control functions. A theoretical foundation for modeling control functions is presented and modeling examples are given for illustration....
Perceptual Audio Hashing Functions
Directory of Open Access Journals (Sweden)
Emin Anarım
2005-07-01
Full Text Available Perceptual hash functions provide a tool for fast and reliable identification of content. We present new audio hash functions based on summarization of the time-frequency spectral characteristics of an audio document. The proposed hash functions are based on the periodicity series of the fundamental frequency and on singular-value description of the cepstral frequencies. They are found, on one hand, to perform very satisfactorily in identification and verification tests, and on the other hand, to be very resilient to a large variety of attacks. Moreover, we address the issue of security of hashes and propose a keying technique, and thereby a key-dependent hash function.
Artin, Emil
2015-01-01
This brief monograph on the gamma function was designed by the author to fill what he perceived as a gap in the literature of mathematics, which often treated the gamma function in a manner he described as both sketchy and overly complicated. Author Emil Artin, one of the twentieth century's leading mathematicians, wrote in his Preface to this book, ""I feel that this monograph will help to show that the gamma function can be thought of as one of the elementary functions, and that all of its basic properties can be established using elementary methods of the calculus."" Generations of teachers
Knopp, Konrad
1996-01-01
This is a one-volume edition of Parts I and II of the classic five-volume set The Theory of Functions prepared by renowned mathematician Konrad Knopp. Concise, easy to follow, yet complete and rigorous, the work includes full demonstrations and detailed proofs.Part I stresses the general foundation of the theory of functions, providing the student with background for further books on a more advanced level.Part II places major emphasis on special functions and characteristic, important types of functions, selected from single-valued and multiple-valued classes.
Institute of Scientific and Technical Information of China (English)
Ding Yi
2009-01-01
In this article, the author derives a functional equation η(s)=［(π/4)s-1/2√2/πг(1-s)sin(πs/2)]η(1-s) of the analytic function η(s) which is defined by η(s)=1-s-3-s-5-s+7-s…for complex variable s with Re s>1, and is defined by analytic continuation for other values of s. The author proves (1) by Ramanujan identity (see [1], [3]). Her method provides a new derivation of the functional equation of Riemann zeta function by using Poisson summation formula.
Quantum Iterated Function Systems
Lozinski, A; Slomczynski, W; Lozinski, Artur; Zyczkowski, Karol; Slomczynski, Wojciech
2003-01-01
Iterated functions system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on the initial point. In an analogous way, we define quantum iterated functions system (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting a QIFS consists of completely positive maps acting in the space of density operators. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant state.
International Nuclear Information System (INIS)
The function of the lungs is primarily the function as a gas exchanger: the venous blood returning to the lungs is arterialized with oxygen in the lungs and the arterialized blood is sent back again to the peripheral tissues of the whole body to be utilized for metabolic oxygenation. Besides the gas exchanging function which we call ''respiratory lung function'' the lungs have functions that have little to do with gas exchange itself. We categorically call the latter function of the lungs as ''nonrespiratory lung function''. The lungs consist of the conductive airways, the gas exchanging units like the alveoli, and the interstitial space that surrounds the former two compartments. The interstitial space contains the blood and lymphatic capillaries, collagen and elastic fibers and cement substances. The conductive airways and the gas exchanging units are directly exposed to the atmosphere that contains various toxic and nontoxic gases, fume and biological or nonbiological particles. Because the conductive airways are equipped with defense mechanisms like mucociliary clearance or coughs to get rid of these toxic gases, particles or locally produced biological debris, we are usually free from being succumbed to ill effects of inhaled materials. By use of nuclear medicine techniques, we can now evaluate mucociliary clearance function, and other nonrespiratory lung functions as well in vivo
DEFF Research Database (Denmark)
Törpel, Bettina
2006-01-01
The objective of this paper is the design of computer supported joint action spaces. It is argued against a view of functionality as residing in computer applications. In such a view the creation of functionality is equivalent to the creation of computer applications. Functionality, in the view...... advocated in this paper, emerges in the specific dynamic interplay of actors, objectives, structures, practices and means. In this view, functionality is the result of creating, harnessing and inhabiting computer supported joint action spaces. The successful creation and further development of a computer...
Renormalization Group Functional Equations
Curtright, Thomas L
2011-01-01
Functional conjugation methods are used to analyze the global structure of various renormalization group trajectories. With minimal assumptions, the methods produce continuous flows from step-scaling {\\sigma} functions, and lead to exact functional relations for the local flow {\\beta} functions, whose solutions may have novel, exotic features, including multiple branches. As a result, fixed points of {\\sigma} are sometimes not true fixed points under continuous changes in scale, and zeroes of {\\beta} do not necessarily signal fixed points of the flow, but instead may only indicate turning points of the trajectories.
Functionalized surfaces and surface functionalization of nanomaterials
Tahir, Muhammad Nawaz
2006-01-01
Nature leads, we follow. But nanotechnologists are in hot pursuit, in designing controllable structures that can mimic naturally occurring and artificially synthesized materials on a common platform. The supramolecular chemistry concerns the investigation of nature principles to produce fascinating complexed and functional molecular assemblies, as well as the utilization of these principles to generate novel devices and materials, potentially useful for sensing, catalysis, transport and other...
Normal Functions As A New Way Of Defining Computable Functions
Directory of Open Access Journals (Sweden)
Leszek Dubiel
2004-01-01
Full Text Available Report sets new method of defining computable functions. This is formalization of traditional function descriptions, so it allows to define functions in very intuitive way. Discovery of Ackermann function proved that not all functions that can be easily computed can be so easily described with Hilbert’s system of recursive functions. Normal functions lack this disadvantage.
Normal Functions as a New Way of Defining Computable Functions
Directory of Open Access Journals (Sweden)
Leszek Dubiel
2004-01-01
Full Text Available Report sets new method of defining computable functions. This is formalization of traditional function descriptions, so it allows to define functions in very intuitive way. Discovery of Ackermann function proved that not all functions that can be easily computed can be so easily described with Hilbert's system of recursive functions. Normal functions lack this disadvantage.
Funkcionalna androgenizacija: Functional hyperandrogenism:
Kocijančič, Andreja; Legan, Mateja
2001-01-01
Functional hyperandrogenism is common endocrinological disorder of premenopausal women characterized by hyperandrogenism, hirsutism with or without androgenic alopecia and chronic anovulation. The controversy regardingthe pathophysiological mechanism underlying the disease still persists. Insulin resistance and hyperinsulinism are now well recognized features of obese women with functional hyperandrogenism and accepted pathogenetic factor of disorder in obese patients. Insulin enhances lutheo...
A Functional HAZOP Methodology
DEFF Research Database (Denmark)
Liin, Netta; Lind, Morten; Jensen, Niels;
2010-01-01
. The functional HAZOP methodology lends itself directly for implementation into a computer aided reasoning tool to perform root cause and consequence analysis. Such a tool can facilitate finding causes and/or consequences far away from the site of the deviation. A functional HAZOP assistant is proposed...
Thyroid function in pregnancy☆
Leung, Angela M.
2012-01-01
Iodine is required for the production of thyroid hormones. Normal thyroid function during pregnancy is important for both the mother and developing fetus. This review discusses the changes in thyroid physiology that occur during pregnancy, the significance of thyroid function tests and thyroid antibody titers assessed during pregnancy, and the potential obstetric complications associated with maternal hypothyroidism.
DEFF Research Database (Denmark)
Gardner, Richard J.; Kiderlen, Markus
, and associative, must be one of 40 explicitly given types. In particular, this is the case for operations between pairs of arbitrary, or continuous, or differentiable functions. The term pointwise means that (f ∗g)(x) = F(f(x), g(x)), for all x ∈ A and some function F of two variables. Several results in the same...
Construction of Resilient Functions
Institute of Scientific and Technical Information of China (English)
ZHANG Jie; WEN Qiao-yan
2005-01-01
Based on the relationship between nonlinearity and resiliency of a multi-output function, we present a method for constructing nonintersecting linear codes from packing design. Through these linear codes, we obtain n-variable, moutput, t-resilient functions with very high nonlinearity.Their nonlinearities are currently the best results for most of cases.
Functional and cognitive grammars
Institute of Scientific and Technical Information of China (English)
Anna Siewierska
2011-01-01
This paper presents a comprehensive review of the functional approach and cognitive approach to the nature of language and its relation to other aspects of human cognition. The paper starts with a brief discussion of the origins and the core tenets of the two approaches in Section 1. Section 2 discusses the similarities and differences between the three full-fledged structural functional grammars subsumed in the functional approach： Halliday＇s Systemic Functional Grammar （SFG）, Dik＇s Functional Grammar （FG）, and Van Valin＇s Role and Reference Grammar （RRG）. Section 3 deals with the major features of the three cognitive frameworks： Langacker＇s Cognitive Grammar （CG）, Goldberg＇s Cognitive Construction Grammar （CCG）, and Croft＇s Radical Construction Grammar （RCG）. Section 4 compares the two approaches and attempts to provide a unified functional-cognitive grammar. In the last section, the author concludes the paper with remarks on the unidirectional shift from functional grammar to cognitive grammar that may indicate a reinterpretation of the traditional relationship between functional and cognitive models of grammar.
... of the clotting process in the body ( in vivo ). A person with normal platelet function test results may still experience excessive bleeding or inappropriate clotting during and after a surgery. Most samples for platelet function testing are only stable for a very short period ...
2003-01-01
This interactive tutorial on MATLAB covers the following: Create M-files, scripts, and functions., Write HELP comments for the functions., Determine the order in which MATLAB chooses to execute entities with identical names.The interactions involve entering MATLAB instructions and observing the outcomes. Self-check questions are provided to help learners determine their level of understanding of the content presented.
Functional Magnetic Resonance Imaging
Voos, Avery; Pelphrey, Kevin
2013-01-01
Functional magnetic resonance imaging (fMRI), with its excellent spatial resolution and ability to visualize networks of neuroanatomical structures involved in complex information processing, has become the dominant technique for the study of brain function and its development. The accessibility of in-vivo pediatric brain-imaging techniques…
Group Contest Success Functions
Münster, Johannes
2008-01-01
Eine contest success function beschreibt, wie in einem Wettkampf die Gewinnwahrscheinlichkeiten von den Einsätzen der Beteiligten abhängen. Dieser Aufsatz verallgemeinert die auf Skaperdas (1996) und Clark und Riis (1998) zurückgehende axiomatische Fundierung von contest success functions, indem er Wettkämpfe zwischen Gruppen untersucht.
DEFF Research Database (Denmark)
Thomsen, Søren Steffen
2009-01-01
Cryptographic hash functions are commonly used in many different areas of cryptography: in digital signatures and in public-key cryptography, for password protection and message authentication, in key derivation functions, in pseudo-random number generators, etc. Recently, cryptographic hash func...
Modeling Protein Domain Function
Baker, William P.; Jones, Carleton "Buck"; Hull, Elizabeth
2007-01-01
This simple but effective laboratory exercise helps students understand the concept of protein domain function. They use foam beads, Styrofoam craft balls, and pipe cleaners to explore how domains within protein active sites interact to form a functional protein. The activity allows students to gain content mastery and an understanding of the…
Pick, Luboš; John, Oldrich; Fucík, Svatopluk
2012-01-01
This is the first part of the second revised and extended edition of a well established monograph. It is an introduction to function spaces defined in terms of differentiability and integrability classes. It provides a catalogue of various spaces and benefits as a handbook for those who use function spaces to study other topics such as partial differential equations. Volum
DEFF Research Database (Denmark)
Gauravaram, Praveen; Knudsen, Lars Ramkilde
2010-01-01
-Damg{\\aa}rd construction are followed in almost all widely used standard hash functions such as MD5 and SHA-1. In the last few years, collision attacks on the MD5 and SHA-1 hash functions have been demonstrated and weaknesses in the Merkle-Damg{\\aa}rd construction have been exposed. The impact of these attacks on some...
... like asthma, chronic obstructive lung disease (COPD), or cystic fibrosis on lung function. ■■ Identify early changes in lung function that might show a need for a change in treatment. ■■ Detect narrowing in the airways. ■■ Decide if a ...
DEFF Research Database (Denmark)
Yazdani, Hossein; Ortiz-Arroyo, Daniel; Kwasnicka, Halina
2016-01-01
In data science, there are important parameters that affect the accuracy of the algorithms used. Some of these parameters are: the type of data objects, the membership assignments, and distance or similarity functions. This paper discusses similarity functions as fundamental elements in membership...
Luten, J.B.
2009-01-01
This book reviews the research on seafood and health, the use and quality aspects of marine lipids and seafood proteins as ingredients in functional foods and consumer acceptance of (marine) functional food. The first chapter covers novel merging areas where seafood may prevent disease and improve h
properties and luminosity functions
Directory of Open Access Journals (Sweden)
Hektor Monteiro
2007-01-01
Full Text Available In this article, we present an investigation of a sample of 1072 stars extracted from the Villanova Catalog of Spectroscopically Identified White Dwarfs (2005 on-line version, studying their distribution in the Galaxy, their physical properties and their luminosity functions. The distances and physical properties of the white dwarfs are determined through interpolation of their (B-V or (b-y colors in model grids. The solar position relative to the Galactic plane, luminosity function, as well as separate functions for each white dwarf spectral type are derived and discussed. We show that the binary fraction does not vary significantly as a function of distance from the Galactic disk out to 100 pc. We propose that the formation rates of DA and non-DAs have changed over time and/or that DAs evolve into non-DA types. The luminosity functions for DAs and DBs have peaks possibly related to a star burst event.
Purely Functional Structured Programming
Obua, Steven
2010-01-01
The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that mainstream programmers can reap the benefits of purely functional programming like easily exploitable parallelism while using familiar structured programming syntax and without knowing concepts like monads. A second advantage is that professional purely functional programmers can often avoid hard to read functional code by using structured programming syntax that is often easier to parse mentally.
DEFF Research Database (Denmark)
Sørensen, A S; Hansen, H; Høgenhaven, H;
1988-01-01
served as controls: 15 patients with a non-neurological but relapsing disorder, psoriasis, and 15 healthy volunteers. Compared with the group of healthy volunteers, a decreased adaptive level of ego functioning was found in the epilepsy groups, regardless of seizure types and EEG findings, and......, to a lesser extent, compared with the psoriasis group. Areas of ego functioning most affected were "reality testing", "cognitive functioning", "integrative functioning" and "regulation and control of drives". Patients with more than one type of seizure were the most affected, as were patients who were younger...... than 15 years when the disease began. The number of anticonvulsants administered did not influence the results. No difference on adaptive level of ego functioning was found between the group with primary generalized epilepsy and the group with temporal lobe epilepsy. Similarly, the temporal lobe...
Ramsay, J O
1997-01-01
Scientists today collect samples of curves and other functional observations. This monograph presents many ideas and techniques for such data. Included are expressions in the functional domain of such classics as linear regression, principal components analysis, linear modelling, and canonical correlation analysis, as well as specifically functional techniques such as curve registration and principal differential analysis. Data arising in real applications are used throughout for both motivation and illustration, showing how functional approaches allow us to see new things, especially by exploiting the smoothness of the processes generating the data. The data sets exemplify the wide scope of functional data analysis; they are drwan from growth analysis, meterology, biomechanics, equine science, economics, and medicine. The book presents novel statistical technology while keeping the mathematical level widely accessible. It is designed to appeal to students, to applied data analysts, and to experienced researc...
Minguzzi, E.
2010-09-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K + relation (Seifert’s relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg’s and Levin’s theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K + (or Seifert) relation which indeed turns out to be the intersection of the time or temporal orderings. This result tells us in which circumstances it is possible to recover the chronological or causal relation starting from the set of time or temporal functions allowed by the spacetime. Moreover, it is proved that a chronological spacetime in which the closure of the causal relation is transitive (for instance a reflective spacetime) admits a semi-time function. Along the way a new proof avoiding smoothing techniques is given that the existence of a time function implies stable causality, and a new short proof of the equivalence between K-causality and stable causality is given which takes advantage of Levin’s theorem and smoothing techniques.
Minguzzi, E
2009-01-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K^+ relation (Seifert's relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg's and Levin's theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K^+ (or Seifert) relation which indeed...
Balcan, Maria-Florina
2010-01-01
There has recently been significant interest in the machine learning community on understanding and using submodular functions. Despite this recent interest, little is known about submodular functions from a learning theory perspective. Motivated by applications such as pricing goods in economics, this paper considers PAC-style learning of submodular functions in a distributional setting. A problem instance consists of a distribution on {0,1}^n and a real-valued function on {0,1}^n that is non-negative, monotone and submodular. We are given poly(n) samples from this distribution, along with the values of the function at those sample points. The task is to approximate the value of the function to within a multiplicative factor at subsequent sample points drawn from the same distribution, with sufficiently high probability. We prove several results for this problem. (1) If the function is Lipschitz and the distribution is a product distribution, such as the uniform distribution, then a good approximation is pos...
International Nuclear Information System (INIS)
The modulus squared of a class of wavefunctions defined on phase space is used to define a generalized family of Q or Husimi functions. A parameter λ specifies orderings in a mapping from the operator vertical bar ψ)(σ vertical bar to the corresponding phase space wavefunction, where σ is a given fiducial vector. The choice λ = 0 specifies the Weyl mapping and the Q-function so obtained is the usual one when vertical bar σ) is the vacuum state. More generally, any choice of λ in the range (-1, 1) corresponds to orderings varying between standard and anti-standard. For all such orderings the generalized Q-functions are non-negative by construction. They are shown to be proportional to the expectation of the system state ρ-hat with respect to a generalized displaced squeezed state which depends on λ and position (p, q) in phase space. Thus, when a system has been prepared in the state ρ-hat, a generalized Q-function is proportional to the probability of finding it in the generalized squeezed state. Any such Q-function can also be written as the smoothing of the Wigner function for the system state ρ-hat by convolution with the Wigner function for the generalized squeezed state
Unification of Filled Function and Tunnelling Function in Global Optimization
Institute of Scientific and Technical Information of China (English)
Wei Wang; Yong-jian Yang; Lian-sheng Zhang
2007-01-01
In this paper, two auxiliary functions for global optimization are proposed. These two auxiliary functions possess all characters of tunnelling functions and filled functions under certain general assumptions.Thus, they can be considered as the unification of filled function and tunnelling function. Moreover, the process of tunneling or filling for global optimization can be unified as the minimization of such auxiliary functions.Result of numerical experiments shows that such two auxiliary functions are effective.
Polysheroidal periodic functions
International Nuclear Information System (INIS)
Separation of variables in the Helmholtz N-dimensional (N≥4) equation in polyspheroidal coordinate systems leads to the necessity of solving equations going over into equations for polyspheroidal periodic functions used for solving the two-centre problem in quantum mechanics, the three-body problem with Coulomb interaction, etc. For these functions the expansions are derived in terms of the Jacobi polynomials and Bessel functions. Their basic properties, asymptotics are considered. The algorithm of their computer calculations is developed. The results of numerical calculations are given
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Rechberger, Christian; Thomsen, Søren Steffen
2007-01-01
In this paper we propose the Grindahl hash functions, which are based on components of the Rijndael algorithm. To make collision search sufficiently difficult, this design has the important feature that no low-weight characteristics form collisions, and at the same time it limits access...... to the state. We propose two concrete hash functions, Grindahl-256 and Grindahl-512 with claimed security levels with respect to collision, preimage and second preimage attacks of 2^128 and 2^256, respectively. Both proposals have lower memory requirements than other hash functions at comparable speeds...
Directory of Open Access Journals (Sweden)
Carlos A. Berenstein
1980-01-01
Full Text Available We show that any mean-periodic function f can be represented in terms of exponential-polynomial solutions of the same convolution equation f satisfies, i.e., u∗f=0(μ∈E′(ℝn. This extends to n-variables the work of L. Schwartz on mean-periodicity and also extends L. Ehrenpreis' work on partial differential equations with constant coefficients to arbitrary convolutors. We also answer a number of open questions about mean-periodic functions of one variable. The basic ingredient is our work on interpolation by entire functions in one and several complex variables.
Restoration of Shoulder Function.
Boe, Chelsea C; Elhassan, Bassem T
2016-08-01
Restoration of shoulder function in patients with brachial plexus injury can be challenging. Initial reported efforts were focused on stabilizing the shoulder, improving inferior subluxation and restoring abduction and flexion of the joint. Recent advancements and improved understanding of coordinated shoulder motion and the biomechanical properties of the muscles around the shoulder applicable to tendon transfer have expanded available surgical options to improve shoulder function, specifically external rotation. Despite the advances in reconstructive options, brachial plexus injury remains a serious problem that requires complex surgical solutions, prolonged recovery, and acceptance of functional loss. PMID:27387074
Quantum iterated function systems.
Łoziński, Artur; Zyczkowski, Karol; Słomczyński, Wojciech
2003-10-01
An iterated function system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on an initial point. In an analogous way, we define a quantum IFS (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting, a QIFS consists of completely positive maps acting in the space of density operators. This formalism is designed to describe certain problems of nonunitary quantum dynamics. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant states.
Mathai, AM
2009-01-01
The two main topics emphasized in this book, special functions and fractional calculus, are currently under fast development in theory and application to many problems in statistics, physics, and engineering, particularly in condensed matter physics, plasma physics, and astrophysics. The book begins by setting forth definitions, contours, existence conditions, and particular cases of the H-function. The authors then deal with Laplace, Fourier, Hankel, and other transforms. As these relations are explored, fractional calculus and its relations to H-functions emerge with important results on fra
[Vascular endothelial Barrier Function].
Ivanov, A N; Puchinyan, D M; Norkin, I A
2015-01-01
Endothelium is an important regulator of selective permeability of the vascular wall for different molecules and cells. This review summarizes current data on endothelial barrier function. Endothelial glycocalyx structure, its function and role in the molecular transport and leukocytes migration across the endothelial barrier are discussed. The mechanisms of transcellular transport of macromolecules and cell migration through endothelial cells are reviewed. Special section of this article addresses the structure and function of tight and adherens endothelial junction, as well as their importance for the regulation of paracellular transport across the endothelial barrier. Particular attention is paid to the signaling mechanism of endothelial barrier function regulation and the factors that influence on the vascular permeability.
Directory of Open Access Journals (Sweden)
N. Carella
2013-09-01
Full Text Available A new unconditional inequality of the totient function is contributed to the literature. This result is associated with various unsolved problems about the distribution of prime numbers.
Fundamentals of functional analysis
Farenick, Douglas
2016-01-01
This book provides a unique path for graduate or advanced undergraduate students to begin studying the rich subject of functional analysis with fewer prerequisites than is normally required. The text begins with a self-contained and highly efficient introduction to topology and measure theory, which focuses on the essential notions required for the study of functional analysis, and which are often buried within full-length overviews of the subjects. This is particularly useful for those in applied mathematics, engineering, or physics who need to have a firm grasp of functional analysis, but not necessarily some of the more abstruse aspects of topology and measure theory normally encountered. The reader is assumed to only have knowledge of basic real analysis, complex analysis, and algebra. The latter part of the text provides an outstanding treatment of Banach space theory and operator theory, covering topics not usually found together in other books on functional analysis. Written in a clear, concise manner,...
2011-01-01
This book reviews the results of recent research on new materials arising from progress in polymer, ceramic, sensor, and fuel cell technology, including advanced inorganic-organic-hybrid polymeric materials, high functional sensor, and microbial fuel cells.
Kellerstein, M; Verbaarschot, J J M
2016-01-01
The behavior of quenched Dirac spectra of two-dimensional lattice QCD is consistent with spontaneous chiral symmetry breaking which is forbidden according to the Coleman-Mermin-Wagner theorem. One possible resolution of this paradox is that, because of the bosonic determinant in the partially quenched partition function, the conditions of this theorem are violated allowing for spontaneous symmetry breaking in two dimensions or less. This goes back to work by Niedermaier and Seiler on nonamenable symmetries of the hyperbolic spin chain and earlier work by two of the auhtors on bosonic partition functions at nonzero chemical potential. In this talk we discuss chiral symmetry breaking for the bosonic partition function of QCD at nonzero isospin chemical potential and a bosonic random matrix theory at imaginary chemical potential and compare the results with the fermionic counterpart. In both cases the chiral symmetry group of the bosonic partition function is noncompact.
... Spread the Word Shop AAP Find a Pediatrician Family Life Medical Home Family Dynamics Adoption & Foster Care ... Español Text Size Email Print Share Normal Functioning Family Page Content Article Body Is there any way ...
Pair Correlation Function Integrals
DEFF Research Database (Denmark)
Wedberg, Nils Hejle Rasmus Ingemar; O'Connell, John P.; Peters, Günther H.J.;
2011-01-01
-distance behavior of radial distribution functions is determined by requiring that the corresponding direct correlation functions follow certain approximations at long distances. We have briefly described the method and tested its performance in previous communications [R. Wedberg, J. P. O’Connell, G. H. Peters......, and J. Abildskov, Mol. Simul. 36, 1243 (2010); Fluid Phase Equilib. 302, 32 (2011)], but describe here its theoretical basis more thoroughly and derive long-distance approximations for the direct correlation functions. We describe the numerical implementation of the method in detail, and report...... numerical tests complementing previous results. Pure molecular fluids are here studied in the isothermal-isobaric ensemble with isothermal compressibilities evaluated from the total correlation function integrals and compared with values derived from volume fluctuations. For systems where the radial...
Catalytic Functions of Standards
K. Blind (Knut)
2009-01-01
textabstractThe three different areas and the examples have illustrated several catalytic functions of standards for innovation. First, the standardisation process reduces the time to market of inventions, research results and innovative technologies. Second, standards themselves promote the diffusi
Reasoning about Function Objects
Nordio, Martin; Calcagno, Cristiano; Meyer, Bertrand; Müller, Peter; Tschannen, Julian
Modern object-oriented languages support higher-order implementations through function objects such as delegates in C#, agents in Eiffel, or closures in Scala. Function objects bring a new level of abstraction to the object-oriented programming model, and require a comparable extension to specification and verification techniques. We introduce a verification methodology that extends function objects with auxiliary side-effect free (pure) methods to model logical artifacts: preconditions, postconditions and modifies clauses. These pure methods can be used to specify client code abstractly, that is, independently from specific instantiations of the function objects. To demonstrate the feasibility of our approach, we have implemented an automatic prover, which verifies several non-trivial examples.
Center for Functional Nanomaterials
Federal Laboratory Consortium — The Center for Functional Nanomaterials (CFN) explores the unique properties of materials and processes at the nanoscale. The CFN is a user-oriented research center...
Ghrelin and Functional Dyspepsia
Takashi Akamizu; Hiroshi Iwakura; Hiroyuki Ariyasu; Kenji Kangawa
2010-01-01
The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD). While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it ...
Production Functions Behaving Badly
DEFF Research Database (Denmark)
Fredholm, Thomas
This paper reconsiders Anwar Shaikh's critique of the neoclassical theory of growth and distribution based on its use of aggregate production functions. This is done by reconstructing and extending Franklin M. Fisher's 1971 computer simulations, which Shaikh used to support his critique. Together...... with other recent extensions to Shaikh's seminal work, my results support and strengthen the evidence against the use of aggregate production functions....
Pankaj Talwar; Suryakant Hayatnagarkar
2015-01-01
With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give ins...
Griffel, DH
2002-01-01
A stimulating introductory text, this volume examines many important applications of functional analysis to mechanics, fluid mechanics, diffusive growth, and approximation. Detailed enough to impart a thorough understanding, the text is also sufficiently straightforward for those unfamiliar with abstract analysis. Its four-part treatment begins with distribution theory and discussions of Green's functions. Essentially independent of the preceding material, the second and third parts deal with Banach spaces, Hilbert space, spectral theory, and variational techniques. The final part outlines the
Purely Functional Structured Programming
Obua, Steven
2010-01-01
The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that m...
Instance based function learning
Ramon, Jan; De Raedt, Luc
1999-01-01
The principles of instance based function learning are presented. In IBFL one is given a set of positive examples of a functional predicate. These examples are true ground facts that illustrate the input output behaviour of the predicate. The purpose is then to predict the output of the predicate given a new input. Further assumptions are that there is no background theory and that the inputs and outputs of the predicate consist of structured terms. IBFL is a novel technique that addresses th...
Daniel A. Barone; Krieger, Ana C.
2015-01-01
The importance of sleep can be ascertained by noting the effects of its loss, which tends to be chronic and partial, on cognition, mood, alertness, and overall health. Many theories have been put forth to explain the function of sleep in humans, including proposals based on energy conservation, ecological adaptations, neurocognitive function, neural plasticity, nervous system and physical health, and performance. Most account for only a portion of sleep behavior and few are based on strong ex...
O'Farrell, Anthony G.
1991-01-01
Ever since the famous thesis of Frostman, capacities have been important in many areas of function theory. In this talk I shall be concerned only with one–variable function theory on arbitrary open subsets of the complex plane, C. It is important to stress that the open sets need not be connected. I will discuss the use of analytic capacities in connection with problems of removable singularities, holomorphic approximation, and boundary smoothness. A brief reference to the applications ...
Green's functions with applications
Duffy, Dean G
2015-01-01
This second edition systematically leads readers through the process of developing Green's functions for ordinary and partial differential equations. In addition to exploring the classical problems involving the wave, heat, and Helmholtz equations, the book includes special sections on leaky modes, water waves, and absolute/convective instability. The book helps readers develop an intuition about the behavior of Green's functions, and considers the questions of the computational efficiency and possible methods for accelerating the process.
Functions & Features of Idioms
Institute of Scientific and Technical Information of China (English)
周来纳
2015-01-01
Idioms, or conventionalized multiword expressions, often but not always non-literal, are hardly marginal in English, though they have been relatively neglected in lexical studies of the language. This neglect is especially evident in respect of the functions of idioms. The aim of this article, accordingly, is to account for the functions of idioms by analyzing what they do with the features of idioms.
International Nuclear Information System (INIS)
It is being argued that even in non-relativistic quantum mechanics the coordinate and momentum variables cannot be interpreted directly as observables. Only by defining these by suitable test bodies can we obtain verifiable predictions. When these arguments are implemented on a Wigner distribution it is shown that positive phase space probabilities always ensue, and hence this function can be used as a quantum mechanical phase space function. (author)
Handbook of functional equations functional inequalities
2014-01-01
As Richard Bellman has so elegantly stated at the Second International Conference on General Inequalities (Oberwolfach, 1978), “There are three reasons for the study of inequalities: practical, theoretical, and aesthetic.” On the aesthetic aspects, he said, “As has been pointed out, beauty is in the eye of the beholder. However, it is generally agreed that certain pieces of music, art, or mathematics are beautiful. There is an elegance to inequalities that makes them very attractive.” The content of the Handbook focuses mainly on both old and recent developments on approximate homomorphisms, on a relation between the Hardy–Hilbert and the Gabriel inequality, generalized Hardy–Hilbert type inequalities on multiple weighted Orlicz spaces, half-discrete Hilbert-type inequalities, on affine mappings, on contractive operators, on multiplicative Ostrowski and trapezoid inequalities, Ostrowski type inequalities for the Riemann–Stieltjes integral, means and related functional inequalities, Weighted G...
The Cosmological Time Function
Andersson, L; Howard, R
1998-01-01
Let $(M,g)$ be a time oriented Lorentzian manifold and $d$ the Lorentzian distance on $M$. The function $\\tau(q):=\\sup_{p< q} d(p,q)$ is the cosmological time function of $M$, where as usual $p< q$ means that $p$ is in the causal past of $q$. This function is called regular iff $\\tau(q) < \\infty$ for all $q$ and also $\\tau \\to 0$ along every past inextendible causal curve. If the cosmological time function $\\tau$ of a space time $(M,g)$ is regular it has several pleasant consequences: (1) It forces $(M,g)$ to be globally hyperbolic, (2) every point of $(M,g)$ can be connected to the initial singularity by a rest curve (i.e., a timelike geodesic ray that maximizes the distance to the singularity), (3) the function $\\tau$ is a time function in the usual sense, in particular (4) $\\tau$ is continuous, in fact locally Lipschitz and the second derivatives of $\\tau$ exist almost everywhere.
Space race functional responses.
Sjödin, Henrik; Brännström, Åke; Englund, Göran
2015-02-22
We derive functional responses under the assumption that predators and prey are engaged in a space race in which prey avoid patches with many predators and predators avoid patches with few or no prey. The resulting functional response models have a simple structure and include functions describing how the emigration of prey and predators depend on interspecific densities. As such, they provide a link between dispersal behaviours and community dynamics. The derived functional response is general but is here modelled in accordance with empirically documented emigration responses. We find that the prey emigration response to predators has stabilizing effects similar to that of the DeAngelis-Beddington functional response, and that the predator emigration response to prey has destabilizing effects similar to that of the Holling type II response. A stability criterion describing the net effect of the two emigration responses on a Lotka-Volterra predator-prey system is presented. The winner of the space race (i.e. whether predators or prey are favoured) is determined by the relationship between the slopes of the species' emigration responses. It is predicted that predators win the space race in poor habitats, where predator and prey densities are low, and that prey are more successful in richer habitats. PMID:25589602
Directory of Open Access Journals (Sweden)
Samson Z Assefa
2015-08-01
Full Text Available Sleep is a ubiquitous component of animal life including birds and mammals. The exact function of sleep has been one of the mysteries of biology. A considerable number of theories have been put forward to explain the reason(s for the necessity of sleep. To date, while a great deal is known about what happens when animals sleep, there is no definitive comprehensive explanation as to the reason that sleep is an inevitable part of animal functioning. It is well known that sleep is a homeostatically regulated body process, and that prolonged sleep deprivation is fatal in animals. In this paper, we present some of the theories as to the functions of sleep and provide a review of some hypotheses as to the overall physiologic function of sleep. To better understand the purpose for sleeping, we review the effects of sleep deprivation on physical, neurocognitive and psychic function. A better understanding of the purpose for sleeping will be a great advance in our understanding of the nature of the animal kingdom, including our own.
Space race functional responses.
Sjödin, Henrik; Brännström, Åke; Englund, Göran
2015-02-22
We derive functional responses under the assumption that predators and prey are engaged in a space race in which prey avoid patches with many predators and predators avoid patches with few or no prey. The resulting functional response models have a simple structure and include functions describing how the emigration of prey and predators depend on interspecific densities. As such, they provide a link between dispersal behaviours and community dynamics. The derived functional response is general but is here modelled in accordance with empirically documented emigration responses. We find that the prey emigration response to predators has stabilizing effects similar to that of the DeAngelis-Beddington functional response, and that the predator emigration response to prey has destabilizing effects similar to that of the Holling type II response. A stability criterion describing the net effect of the two emigration responses on a Lotka-Volterra predator-prey system is presented. The winner of the space race (i.e. whether predators or prey are favoured) is determined by the relationship between the slopes of the species' emigration responses. It is predicted that predators win the space race in poor habitats, where predator and prey densities are low, and that prey are more successful in richer habitats.
Renal Function in Hypothyroidism
International Nuclear Information System (INIS)
Background Hypothyroidism induces significant changes in the function of organ systems such as the heart, muscles and brain. Renal function is also influenced by thyroid status. Physiological effects include changes in water and electrolyte metabolism, notably hyponatremia, and reliable alterations of renal hemodynamics, including decrements in renal blood flow, renal plasma flow, glomerular filtration rate (GFR). Objective Renal function is profoundly influenced by thyroid status; the purpose of the present study was to determine the relationship between renal function and thyroid status of patients with hypothyroidism. Design and Patients In 5 patients with primary hypothyroidism and control group renal functions are measured by serum creatinine and glomerular filtration rate (GFR) using modified in diet renal disease (MDRD) formula. Result In hypothyroidism, mean serum creatinine increased and mean estimated GFR decreased, compared to the control group mean serum creatinine decreased and mean estimated GFR Increased. The hypothyroid patients showed elevated serum creatinine levels (> 1.1mg/dl) compared to control group (p value .000). In patients mean estimated GFR decreased, compared to mean estimated GFR increased in the control group (p value= .002).
Talwar, Pankaj; Hayatnagarkar, Suryakant
2015-01-01
With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give insight on the events in fertilization of the oocyte. The sperms need to get nutrition from the seminal plasma in the form of fructose and citrate (this can be assessed by fructose qualitative and quantitative estimation, citrate estimation). They should be protected from the bad effects of pus cells and reactive oxygen species (ROS) (leukocyte detection test, ROS estimation). Their number should be in sufficient in terms of (count), structure normal to be able to fertilize eggs (semen morphology). Sperms should have intact and functioning membrane to survive harsh environment of vagina and uterine fluids (vitality and hypo-osmotic swelling test), should have good mitochondrial function to be able to provide energy (mitochondrial activity index test). They should also have satisfactory acrosome function to be able to burrow a hole in zona pellucida (acrosome intactness test, zona penetration test). Finally, they should have properly packed DNA in the nucleus to be able to transfer the male genes (nuclear chromatic decondensation test) to the oocyte during fertilization. PMID:26157295
Directory of Open Access Journals (Sweden)
Pankaj Talwar
2015-01-01
Full Text Available With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give insight on the events in fertilization of the oocyte. The sperms need to get nutrition from the seminal plasma in the form of fructose and citrate (this can be assessed by fructose qualitative and quantitative estimation, citrate estimation. They should be protected from the bad effects of pus cells and reactive oxygen species (ROS (leukocyte detection test, ROS estimation. Their number should be in sufficient in terms of (count, structure normal to be able to fertilize eggs (semen morphology. Sperms should have intact and functioning membrane to survive harsh environment of vagina and uterine fluids (vitality and hypo-osmotic swelling test, should have good mitochondrial function to be able to provide energy (mitochondrial activity index test. They should also have satisfactory acrosome function to be able to burrow a hole in zona pellucida (acrosome intactness test, zona penetration test. Finally, they should have properly packed DNA in the nucleus to be able to transfer the male genes (nuclear chromatic decondensation test to the oocyte during fertilization.
DEFF Research Database (Denmark)
Nielsen, Line A.; Zois, Nora Elisabeth; Pedersen, Henrik D.;
2007-01-01
Background: Clinical studies investigating platelet function in dogs have had conflicting results that may be caused by normal physiologic variation in platelet response to agonists. Objectives: The objective of this study was to investigate platelet function in clinically healthy dogs of 4...... different breeds by whole-blood aggregometry and with a point-of-care platelet function analyzer (PFA-100), and to evaluate the effect of acetylsalicylic acid (ASA) administration on the results from both methods. Methods: Forty-five clinically healthy dogs (12 Cavalier King Charles Spaniels [CKCS], 12...... applied. However, the importance of these breed differences remains to be investigated. The PFA-100 method with Col + Epi as agonists, and ADP-induced platelet aggregation appear to be sensitive to ASA in dogs....
Ghrelin and Functional Dyspepsia
Directory of Open Access Journals (Sweden)
Takashi Akamizu
2010-01-01
Full Text Available The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD. While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it may play a pathophysiological role in FD. It is also possible that the functional abnormalities in FD may affect ghrelin production in the stomach. Plasma ghrelin levels are reported to be altered in FD, correlating with FD symptom score. Furthermore, some patients with FD suffer from anorexia with body-weight loss. As ghrelin increases gastric emptying and promotes feeding, ghrelin therapy may be a new approach to the treatment of FD.
Spaces of continuous functions
Groenewegen, G L M
2016-01-01
The space C(X) of all continuous functions on a compact space X carries the structure of a normed vector space, an algebra and a lattice. On the one hand we study the relations between these structures and the topology of X, on the other hand we discuss a number of classical results according to which an algebra or a vector lattice can be represented as a C(X). Various applications of these theorems are given. Some attention is devoted to related theorems, e.g. the Stone Theorem for Boolean algebras and the Riesz Representation Theorem. The book is functional analytic in character. It does not presuppose much knowledge of functional analysis; it contains introductions into subjects such as the weak topology, vector lattices and (some) integration theory.
Algal functional annotation tool
Energy Technology Data Exchange (ETDEWEB)
Lopez, D. [UCLA; Casero, D. [UCLA; Cokus, S. J. [UCLA; Merchant, S. S. [UCLA; Pellegrini, M. [UCLA
2012-07-01
The Algal Functional Annotation Tool is a web-based comprehensive analysis suite integrating annotation data from several pathway, ontology, and protein family databases. The current version provides annotation for the model alga Chlamydomonas reinhardtii, and in the future will include additional genomes. The site allows users to interpret large gene lists by identifying associated functional terms, and their enrichment. Additionally, expression data for several experimental conditions were compiled and analyzed to provide an expression-based enrichment search. A tool to search for functionally-related genes based on gene expression across these conditions is also provided. Other features include dynamic visualization of genes on KEGG pathway maps and batch gene identifier conversion.
Choice probability generating functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2010-01-01
This paper establishes that every random utility discrete choice model (RUM) has a representation that can be characterized by a choice-probability generating function (CPGF) with specific properties, and that every function with these specific properties is consistent with a RUM. The choice...... probabilities from the RUM are obtained from the gradient of the CPGF. Mixtures of RUM are characterized by logarithmic mixtures of their associated CPGF. The paper relates CPGF to multivariate extreme value distributions, and reviews and extends methods for constructing generating functions for applications....... The choice probabilities of any ARUM may be approximated by a cross-nested logit model. The results for ARUM are extended to competing risk survival models....
Functional Programming Using F#
DEFF Research Database (Denmark)
Hansen, Michael Reichhardt; Rischel, Hans
. Coverage also includes advanced features in the .NET library, the imperative features of F# and topics such as text processing, sequences, computation expressions and asynchronous computation. With a broad spectrum of examples and exercises, the book is perfect for courses in functional programming......This comprehensive introduction to the principles of functional programming using F# shows how to apply basic theoretical concepts to produce succinct and elegant programs. It demonstrates the role of functional programming in a wide spectrum of applications including databases and systems...... and for self-study. Enhancing its use as a text is an accompanying website with downloadable programs, lecture slides, a mini-projects and links to further F# sources....
Quantal density functional theory
Sahni, Viraht
2016-01-01
This book deals with quantal density functional theory (QDFT) which is a time-dependent local effective potential theory of the electronic structure of matter. The treated time-independent QDFT constitutes a special case. In the 2nd edition, the theory is extended to include the presence of external magnetostatic fields. The theory is a description of matter based on the ‘quantal Newtonian’ first and second laws which is in terms of “classical” fields that pervade all space, and their quantal sources. The fields, which are explicitly defined, are separately representative of electron correlations due to the Pauli exclusion principle, Coulomb repulsion, correlation-kinetic, correlation-current-density, and correlation-magnetic effects. The book further describes Schrödinger theory from the new physical perspective of fields and quantal sources. It also describes traditional Hohenberg-Kohn-Sham DFT, and explains via QDFT the physics underlying the various energy functionals and functional derivatives o...
Protein Functionalized Nanodiamond Arrays
Directory of Open Access Journals (Sweden)
Liu YL
2010-01-01
Full Text Available Abstract Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.
International Nuclear Information System (INIS)
Dynamic function studies can be defined as a measure of the variation of a quantity of a substance in an organ with time. Such studies are clinically useful only when the underlying physiological model is realistic. Usually the measurements are of three kinds: the uptake function, the transit function and the removal function. Sensitivity of these measurements can be enhanced in several clinical situations by intervention, such as exercise or drugs. It is possible to display a nuclear image in a variety of ways through computer manipulations which are justified only if based on a valid physiological model. The newer radiopharmaceuticals have also increased the range of functions that can be studied, especially in the case of the heart and the brain. Positron emission tomography (PET) images are fascinating but they are prohibitively expensive and routine clinical nuclear medicine will have to rely on information obtained with single photon emission computer tomography (SPECT). In the diagnosis of cancer, the instrument alone would not improve the diagnosis. It is necessary to have radiopharmaceuticals with a high degree of specificity of uptake. This can possibly be achieved with immunoscintigraphy. There also, the kinetics of uptake of the labelled antibody enable one to differentiate specific from non-specific uptake. The need for good reliable dynamic function studies is as great in the developing as in the developed countries, but a nuclear medicine specialist in a developing country would need more skills and experience because of the heavy odds against which one would be working. (author). 43 refs, 2 figs
Chromatin Structure and Function
Wolffe, Alan P
1999-01-01
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active
Block, Ned
1996-01-01
What is Functionalism? Functionalism is one of the major proposals that have been offered as solutions to the mind/body problem. Solutions to the mind/body problem usually try to answer questions such as: What is the ultimate nature of the mental? At the most general level, what makes a mental state mental? Or more specifically, What do thoughts have in common in virtue of which they are thoughts? That is, what makes a thought a thought? What makes a pain a pain? Cartesian Dualism said the ul...
Sarason, Donald
2007-01-01
Complex Function Theory is a concise and rigorous introduction to the theory of functions of a complex variable. Written in a classical style, it is in the spirit of the books by Ahlfors and by Saks and Zygmund. Being designed for a one-semester course, it is much shorter than many of the standard texts. Sarason covers the basic material through Cauchy's theorem and applications, plus the Riemann mapping theorem. It is suitable for either an introductory graduate course or an undergraduate course for students with adequate preparation. The first edition was published with the title Notes on Co
Clocks and cardiovascular function
McLoughlin, Sarah C.; Haines, Philip; FitzGerald, Garret A.
2016-01-01
Circadian clocks in central and peripheral tissues enable the temporal synchronization and organization of molecular and physiological processes of rhythmic animals, allowing optimum functioning of cells and organisms at the most appropriate time of day. Disruption of circadian rhythms, from external or internal forces, leads to widespread biological disruption and is postulated to underlie many human conditions, such as the incidence and timing of cardiovascular disease. Here, we describe in vivo and in vitro methodology relevant to studying the role of circadian rhythms in cardiovascular function and dysfunction PMID:25707279
Algal functional annotation tool
Energy Technology Data Exchange (ETDEWEB)
2012-07-12
Abstract BACKGROUND: Progress in genome sequencing is proceeding at an exponential pace, and several new algal genomes are becoming available every year. One of the challenges facing the community is the association of protein sequences encoded in the genomes with biological function. While most genome assembly projects generate annotations for predicted protein sequences, they are usually limited and integrate functional terms from a limited number of databases. Another challenge is the use of annotations to interpret large lists of 'interesting' genes generated by genome-scale datasets. Previously, these gene lists had to be analyzed across several independent biological databases, often on a gene-by-gene basis. In contrast, several annotation databases, such as DAVID, integrate data from multiple functional databases and reveal underlying biological themes of large gene lists. While several such databases have been constructed for animals, none is currently available for the study of algae. Due to renewed interest in algae as potential sources of biofuels and the emergence of multiple algal genome sequences, a significant need has arisen for such a database to process the growing compendiums of algal genomic data. DESCRIPTION: The Algal Functional Annotation Tool is a web-based comprehensive analysis suite integrating annotation data from several pathway, ontology, and protein family databases. The current version provides annotation for the model alga Chlamydomonas reinhardtii, and in the future will include additional genomes. The site allows users to interpret large gene lists by identifying associated functional terms, and their enrichment. Additionally, expression data for several experimental conditions were compiled and analyzed to provide an expression-based enrichment search. A tool to search for functionally-related genes based on gene expression across these conditions is also provided. Other features include dynamic visualization of genes
Rarefied elliptic hypergeometric functions
Spiridonov, V P
2016-01-01
We prove exact evaluation formulae for two multiple rarefied elliptic beta integrals related to the simplest lens space. These integrals generalize the multiple type I and II van Diejen-Spiridonov integrals attached to the root system $C_n$. Symmetries of the rarefied elliptic analogue of the Euler-Gauss hypergeometric function are described and the corresponding generalization of the hypergeometric equation is constructed. An extension of the latter function to the root system $C_n$ and applications to some eigenvalue problems are briefly discussed.
Gómez-Romero, Pedro; Sanchez, Clément
2004-04-01
Functional Hybrid Materials consist of both organic and inorganic components, assembled for the purpose of generating desirable properties and functionalities. The aim is twofold: to bring out or enhance advantageous chemical, electrochemical, magnetic or electronic characteristics and at the same time to reduce or wholly suppress undesirable properties or effects. Another target is the creation of entirely new material behavior. The vast number of hybrid material components available has opened up a wide and diversified field of fascinating research. In this book, a team of highly renowned experts gives an in-depth overview, illustrating the superiority of well-designed hybrid materials and their potential applications.
Neurally augmented sexual function.
Meloy, S
2007-01-01
Neurally Augmented Sexual Function (NASF) is a technique utilizing epidural electrodes to restore and improve sexual function. Orgasmic dysfunction is common in adult women, affecting roughly one quarter of populations studied. Many male patients suffering from erectile dysfunction are not candidates for phosphdiesterase therapy due to concomitant nitrate therapy. Positioning the electrodes at roughly the level of the cauda equina allows for stimulation of somatic efferents and afferents as well as modifying sympathetic and parasympathetic activity. Our series of women treated by NASF is described. Our experience shows that the evaluation of potential candidates for both correctable causes and psychological screening are important considerations. PMID:17691397
DEFF Research Database (Denmark)
Glaveanu, Vlad Petre
2014-01-01
of their manifold functions that integrates aesthetic and utilitarian, individual and social roles. Ornaments help us to identify and locate, tell or communicate, remind and organise our action, they guide our attention, express and individualise, can generate an experience, beautify as well as re......-present. These functions are illustrated with examples from a study of Easter egg decoration practices in northern Romania. In the end, the ‘meta-function’ of emergence is discussed and consideration is given to the spatial and temporal contexts of ornaments. Future opportunities for theorising ornamentation...
GADRAS Detector Response Function.
Energy Technology Data Exchange (ETDEWEB)
Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.
2014-11-01
The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
@@ Genomics is a biology term appeared ten years ago, used to describe the researches of genomic mapping, sequencing, and structure analysis, etc. Genomics, the first journal for publishing papers on genomics research was born in 1986. In the past decade, the concept of genomics has been widely accepted by scientists who are engaging in biology research. Meanwhile, the research scope of genomics has been extended continuously, from simple gene mapping and sequencing to function genomics study. To reflect the change, genomics is divided into two parts now, the structure genomics and the function genomics.
Bayes Multiple Decision Functions
Wu, Wensong
2011-01-01
This paper deals with the problem of simultaneously making many (M) binary decisions based on one realization of a random data matrix X. M is typically large and X will usually have M rows associated with each of the M decisions to make, but for each row the data may be low dimensional. A Bayesian decision-theoretic approach for this problem is implemented with the overall loss function being a cost-weighted linear combination of Type I and Type II loss functions. The class of loss functions considered allows for the use of the false discovery rate (FDR), false nondiscovery rate (FNR), and missed discovery rate (MDR) in assessing the decision. Through this Bayesian paradigm, the Bayes multiple decision function (BMDF) is derived and an efficient algorithm to obtain the optimal Bayes action is described. In contrast to many works in the literature where the rows of the matrix X are assumed to be stochastically independent, we allow in this paper a dependent data structure with the associations obtained through...
Empirical microeconomics action functionals
Baaquie, Belal E.; Du, Xin; Tanputraman, Winson
2015-06-01
A statistical generalization of microeconomics has been made in Baaquie (2013), where the market price of every traded commodity, at each instant of time, is considered to be an independent random variable. The dynamics of commodity market prices is modeled by an action functional-and the focus of this paper is to empirically determine the action functionals for different commodities. The correlation functions of the model are defined using a Feynman path integral. The model is calibrated using the unequal time correlation of the market commodity prices as well as their cubic and quartic moments using a perturbation expansion. The consistency of the perturbation expansion is verified by a numerical evaluation of the path integral. Nine commodities drawn from the energy, metal and grain sectors are studied and their market behavior is described by the model to an accuracy of over 90% using only six parameters. The paper empirically establishes the existence of the action functional for commodity prices that was postulated to exist in Baaquie (2013).
Deimling, Klaus
1985-01-01
topics. However, only a modest preliminary knowledge is needed. In the first chapter, where we introduce an important topological concept, the so-called topological degree for continuous maps from subsets ofRn into Rn, you need not know anything about functional analysis. Starting with Chapter 2, where infinite dimensions first appear, one should be familiar with the essential step of consider ing a sequence or a function of some sort as a point in the corresponding vector space of all such sequences or functions, whenever this abstraction is worthwhile. One should also work out the things which are proved in § 7 and accept certain basic principles of linear functional analysis quoted there for easier references, until they are applied in later chapters. In other words, even the 'completely linear' sections which we have included for your convenience serve only as a vehicle for progress in nonlinearity. Another point that makes the text introductory is the use of an essentially uniform mathematical languag...
Functional ingredients from microalgae
Buono, S.; Langellotti, A.L.; Martello, A.; Rinna, F.; Fogliano, V.
2014-01-01
A wide variety of natural sources are under investigation to evaluate their possible use for new functional ingredient formulation. Some records attested the traditional and ancient use of wild harvested microalgae as human food but their cultivation for different purposes started about 40 years ago
Holographic Three point Functions
DEFF Research Database (Denmark)
Bissi, Agnese
gravitons and a point like graviton and its dual counterpart, namely two Schur polynomials and a single trace chiral primary. Secondly we compute the one loop correction to planar, non extremal three point functions of two heavy and one light operators, both from the gauge and string side in the Frolov......In this thesis it is addressed the problem of the computation of three point correlation functions within the AdS=CFT correspondence. In the context of the AdS 5=CFT4 correspondence we present three computations. First we compare the results of tree level three point functions of two giant......-Tseytlin regime. Finally we generalize the scalar product of two states belonging to the SO(6) sector of N = 4 SYM with implications on the construction of three point functions of 3 non-BPS operators from the gauge theory side. On the other hand in the AdS4=CFT3 correspondence we compare the computations...
Biggs, William D.
1987-01-01
Defines computerized functional business games as those focusing on decision making and integration in the areas of accounting/finance, marketing, personnel/human resources, and production/operations. Nine currently available games are reviewed and evaluated in the context of a learning model. (Author/LRW)
DEFF Research Database (Denmark)
Sinden, Richard R.; E. Pearson, Christopher; N. Potaman, Vladimir;
1998-01-01
This chapter discusses the structure and function of DNA. DNA occupies a critical role in cells, because it is the source of all intrinsic genetic information. Chemically, DNA is a very stable molecule, a characteristic important for a macromolecule that may have to persist in an intact form...
Functional Maximum Autocorrelation Factors
DEFF Research Database (Denmark)
Larsen, Rasmus; Nielsen, Allan Aasbjerg
2005-01-01
\\verb+~+\\$\\backslash\\$cite{ramsay97} to functional maximum autocorrelation factors (MAF)\\verb+~+\\$\\backslash\\$cite{switzer85,larsen2001d}. We apply the method to biological shapes as well as reflectance spectra. {\\$\\backslash\\$bf Methods}. MAF seeks linear combination of the original variables that maximize autocorrelation between...
functional-differential inequalities
Directory of Open Access Journals (Sweden)
Ludwik Byszewski
1995-01-01
Full Text Available A theorem about a system of strong impulsive degenerate nonlinear parabolic functional-differential inequalities in an arbitrary parabolic set is proved. As a consequence of the theorem, some theorems about impulsive degenerate nonlinear parabolic differential inequalities and the uniqueness of a classical solution of an impulsive degenerate nonlinear parabolic differential problem are established.
Directory of Open Access Journals (Sweden)
Ramesh Kalindri
2014-06-01
Full Text Available Currently, software engineers are increasingly turning to the option of automating functional tests, but not always have successful in this endeavor. Reasons range from low planning until over cost in the process. Some principles that can guide teams in automating these tests are described in this article.
Executive functions in synesthesia
R. Rouw; J. van Driel; K. Knip; K.R. Ridderinkhof
2013-01-01
In grapheme-color synesthesia, a number or letter can evoke two different and possibly conflicting (real and synesthetic) color sensations at the same time. In this study, we investigate the relationship between synesthesia and executive control functions. First, no general skill differences were ob
Laboratory Density Functionals
Giraud, B. G.
2007-01-01
We compare several definitions of the density of a self-bound system, such as a nucleus, in relation with its center-of-mass zero-point motion. A trivial deconvolution relates the internal density to the density defined in the laboratory frame. This result is useful for the practical definition of density functionals.
On Dupree's resonance function
International Nuclear Information System (INIS)
It is shown that Dupree's resonance function has a negative real asymptotic tail, so that the dispersion relation of the renormalized weak turbulence theory leads to unstable high phase velocity waves, even when the average distribution is a Gaussian. A possible explanation of this paradox is proposed
Enzyme design: Functional Frankensteins
Makhlynets, Olga V.; Korendovych, Ivan V.
2016-09-01
An artificial esterase with no known natural structural analogues has been formed via the homo-heptameric self-assembly of a designed peptide. This esterase represents the first report of a functional catalytic triad rationally engineered into a de novo protein framework.
Automatic Functional Harmonic Analysis
de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.
2013-01-01
Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of W
Objectification and Semiotic Function
Santi, George
2011-01-01
The objective of this paper is to study students' difficulties when they have to ascribe the same meaning to different representations of the same mathematical object. We address two theoretical tools that are at the core of Radford's cultural semiotic and Godino's onto-semiotic approaches: objectification and the semiotic function. The analysis…
Smith, Walter T., Jr.; Patterson, John M.
1984-01-01
Literature on analytical methods related to the functional groups of 17 chemical compounds is reviewed. These compounds include acids, acid azides, alcohols, aldehydes, ketones, amino acids, aromatic hydrocarbons, carbodiimides, carbohydrates, ethers, nitro compounds, nitrosamines, organometallic compounds, peroxides, phenols, silicon compounds,…
Thrombocyte and thrombocyte function
Institute of Scientific and Technical Information of China (English)
1997-01-01
970384 The mechanism of preserving platelet func-tion by aprotinin during cardiopulmonary bypass.YANG Tianyu(杨天宇), et al. Anesthesiol &Cardiòpulmon Bypass Lab, Cardiovasc Instit & FuwaiHosp, CAMS & PUMC, Beijing, 100037. Chin Cir J1996; 11(12): 739-742.
Partition density functional theory
Nafziger, Jonathan
Partition density functional theory (PDFT) is a method for dividing a molecular electronic structure calculation into fragment calculations. The molecular density and energy corresponding to Kohn Sham density-functional theory (KS-DFT) may be exactly recovered from these fragments. Each fragment acts as an isolated system except for the influence of a global one-body 'partition' potential which deforms the fragment densities. In this work, the developments of PDFT are put into the context of other fragment-based density functional methods. We developed three numerical implementations of PDFT: One within the NWChem computational chemistry package using basis sets, and the other two developed from scratch using real-space grids. It is shown that all three of these programs can exactly reproduce a KS-DFT calculation via fragment calculations. The first of our in-house codes handles non-interacting electrons in arbitrary one-dimensional potentials with any number of fragments. This code is used to explore how the exact partition potential changes for different partitionings of the same system and also to study features which determine which systems yield non-integer PDFT occupations and which systems are locked into integer PDFT occupations. The second in-house code, CADMium, performs real-space calculations of diatomic molecules. Features of the exact partition potential are studied for a variety of cases and an analytical formula determining singularities in the partition potential is derived. We introduce an approximation for the non-additive kinetic energy and show how this quantity can be computed exactly. Finally a PDFT functional is developed to address the issues of static correlation and delocalization errors in approximations within DFT. The functional is applied to the dissociation of H2 + and H2.
West, J. B.; Elliott, A. R.; Guy, H. J.; Prisk, G. K.
1997-01-01
The lung is exquisitely sensitive to gravity, and so it is of interest to know how its function is altered in the weightlessness of space. Studies on National Aeronautics and Space Administration (NASA) Spacelabs during the last 4 years have provided the first comprehensive data on the extensive changes in pulmonary function that occur in sustained microgravity. Measurements of pulmonary function were made on astronauts during space shuttle flights lasting 9 and 14 days and were compared with extensive ground-based measurements before and after the flights. Compared with preflight measurements, cardiac output increased by 18% during space flight, and stroke volume increased by 46%. Paradoxically, the increase in stroke volume occurred in the face of reductions in central venous pressure and circulating blood volume. Diffusing capacity increased by 28%, and the increase in the diffusing capacity of the alveolar membrane was unexpectedly large based on findings in normal gravity. The change in the alveolar membrane may reflect the effects of uniform filling of the pulmonary capillary bed. Distributions of blood flow and ventilation throughout the lung were more uniform in space, but some unevenness remained, indicating the importance of nongravitational factors. A surprising finding was that airway closing volume was approximately the same in microgravity and in normal gravity, emphasizing the importance of mechanical properties of the airways in determining whether they close. Residual volume was unexpectedly reduced by 18% in microgravity, possibly because of uniform alveolar expansion. The findings indicate that pulmonary function is greatly altered in microgravity, but none of the changes observed so far will apparently limit long-term space flight. In addition, the data help to clarify how gravity affects pulmonary function in the normal gravity environment on Earth.
EXECUTIVE FUNCTIONING IN SCHIZOPHRENIA
Directory of Open Access Journals (Sweden)
Gricel eOrellana
2013-06-01
Full Text Available The executive function (EF is a set of abilities, which allows us to invoke voluntary control of our behavioral responses. These functions enable human beings to develop and carry out plans, make up analogies, obey social rules, solve problems, adapt to unexpected circumstances, do many tasks simultaneously and locate episodes in time and place. EF includes divided attention and sustained attention, working memory, set-shifting, flexibility, planning and the regulation of goal directed behavior and can be defined as a brain function underlying the human faculty to act or think not only in reaction to external events but also in relation with internal goals and states. EF is mostly associated with dorsolateral prefrontal cortex (PFC. Besides EF, PFC is involved in self-regulation of behavior, i.e. the ability to regulate behavior according to internal goals and constraints, particularly in less structured situations. Self-regulation of behavior is subtended by ventral medial /orbital PFC. Impairment of EF is one of the most commonly observed deficits in schizophrenia through the various disease stages. Impairment in tasks measuring conceptualization, planning, cognitive flexibility, verbal fluency, ability to solve complex problems and working memory occur in schizophrenia. Disorders detected by executive tests are consistent with evidence from functional neuroimaging, which have shown PFC dysfunction in patients while performing these kinds of tasks. Schizophrenics also exhibit deficit in odor identifying, decision-making and self-regulation of behavior suggesting dysfunction of the orbital PFC. However, impairment in executive tests is explained by dysfunction of prefronto-striato-thalamic, prefronto-parietal and prefronto-temporal neural networks mainly. Disorders in executive functions may be considered central facts with respect to schizophrenia and it has been suggested that negative symptoms may be explained by that executive dysfunction.
Quasi-extended asymptotic functions
International Nuclear Information System (INIS)
The class F of ''quasi-extended asymptotic functions'' is introduced. It contains all extended asymptotic functions as well as some new asymptotic functions very similar to the Schwartz distributions. On the other hand, every two quasiextended asymptotic functions can be multiplied as opposed to the Schwartz distributions; in particular, the square delta2 of an asymptotic function delta similar to Dirac's delta-function, is constructed as an example
Vestnorden. A functional region?
Directory of Open Access Journals (Sweden)
Grétar Þór Eyþórsson
2013-06-01
Full Text Available This article discusses the issue of what kind of a region Vestnorden is. The need for such a discussion arises from the challenges posed by globalisation for the idea and construction of the West Nordic space, and the need to observe how this regional unit counters these processes. The article is based on an analytical framework which presupposes that a functional region has to consist of four elements. First, whether the space has its own institutions for decision making; second, how far there is economic complementarities among the involved nations and territories; third, to what degree they have common economic interests; and finally, to what extent social, cultural and historical ties exist between the territories involved. The article argues that there is an urgent need to discuss and reorient the institutional functionality of Vestnorden as a regional unit.
DEFF Research Database (Denmark)
Larsen, S H; Wagner, G; Heitmann, B L
2007-01-01
OBJECTIVE: To review the literature on the relationship between obesity and sexual function. METHOD: A search in the medical literature from 1966 and onwards was carried out through Medline and Embase for publications on obesity, in combination with Medical Subject Heading words related to sexual...... function and dysfunction. COMMENTS: Four prospective and seven cross-sectional studies were found describing association between obesity and erectile dysfunction (ED). One cross-sectional study was found describing obesity and female sexual dysfunction (FSD). The prospective studies on ED all demonstrated...... activity among both men and women after weight loss intervention. CONCLUSION: Support for the assumption that obesity is associated with ED was found in both prospective and cross-sectional studies. FSD was not adequately described in the literature and prospective studies are needed here. Results from...
Directory of Open Access Journals (Sweden)
Daniel A. Barone
2015-06-01
Full Text Available The importance of sleep can be ascertained by noting the effects of its loss, which tends to be chronic and partial, on cognition, mood, alertness, and overall health. Many theories have been put forth to explain the function of sleep in humans, including proposals based on energy conservation, ecological adaptations, neurocognitive function, neural plasticity, nervous system and physical health, and performance. Most account for only a portion of sleep behavior and few are based on strong experimental support. In this review, we present theories proposing why sleep is necessary and supporting data demonstrating the effects of inadequate sleep, with the intention of gleaning further information as to its necessity, which remains one of the most perplexing mysteries in biology.
Functional Biomimetic Architectures
Levine, Paul M.
N-substituted glycine oligomers, or 'peptoids,' are a class of sequence--specific foldamers composed of tertiary amide linkages, engendering proteolytic stability and enhanced cellular permeability. Peptoids are notable for their facile synthesis, sequence diversity, and ability to fold into distinct secondary structures. In an effort to establish new functional peptoid architectures, we utilize the copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC) reaction to generate peptidomimetic assemblies bearing bioactive ligands that specifically target and modulate Androgen Receptor (AR) activity, a major therapeutic target for prostate cancer. Additionally, we explore chemical ligation protocols to generate semi-synthetic hybrid biomacromolecules capable of exhibiting novel structures and functions not accessible to fully biosynthesized proteins.
Functionalization of Carbon Nanotubes
Khare, Bishun N. (Inventor); Meyyappan, Meyya (Inventor)
2009-01-01
Method and system for functionalizing a collection of carbon nanotubes (CNTs). A selected precursor gas (e.g., H2 or F2 or CnHm) is irradiated to provide a cold plasma of selected target species particles, such as atomic H or F, in a first chamber. The target species particles are d irected toward an array of CNTs located in a second chamber while suppressing transport of ultraviolet radiation to the second chamber. A CNT array is functionalized with the target species particles, at or below room temperature, to a point of saturation, in an exposure time interval no longer than about 30 sec. *Discrimination against non-target species is provided by (i) use of a target species having a lifetime that is much greater than a lifetime of a non-target species and/or (2) use of an applied magnetic field to discriminate between charged particle trajectories for target species and for non-target species.
DEFF Research Database (Denmark)
Sørensen, A S; Hansen, H; Høgenhaven, H;
1988-01-01
Two groups of epilepsy patients (28 patients with temporal lobe epilepsy and 15 patients with primary generalized epilepsy) entered a study of personality traits related to epilepsy, based on a modification of Bellak's semistructured interview for assessment of ego strength. Two groups of subjects...... served as controls: 15 patients with a non-neurological but relapsing disorder, psoriasis, and 15 healthy volunteers. Compared with the group of healthy volunteers, a decreased adaptive level of ego functioning was found in the epilepsy groups, regardless of seizure types and EEG findings, and...... than 15 years when the disease began. The number of anticonvulsants administered did not influence the results. No difference on adaptive level of ego functioning was found between the group with primary generalized epilepsy and the group with temporal lobe epilepsy. Similarly, the temporal lobe...
DEFF Research Database (Denmark)
Bech-Larsen, Tino; Scholderer, Joachim
2007-01-01
reading of the main principles of the harmonized regulation COM/2003/0424, this situation is about to change. This article reviews the regulatory aspects, the results of consumer research and the marketing strategies regarding the use of health claims for functional foods in Europe, and it comments...... on the lack of correspondence between the new regulation and the marketing experiences and research as regard consumer reactions to health claims.......The fact that the European markets for functional foods generally are less developed, compared to the US and the Japanese markets, has often been attributed to a restrictive and inconsistent health claim legislation in and between the European countries. With the European Parliament's second...
Nuclear Parton Distribution Functions
Energy Technology Data Exchange (ETDEWEB)
I. Schienbein, J.Y. Yu, C. Keppel, J.G. Morfin, F. Olness, J.F. Owens
2009-06-01
We study nuclear effects of charged current deep inelastic neutrino-iron scattering in the framework of a {chi}{sup 2} analysis of parton distribution functions (PDFs). We extract a set of iron PDFs which are used to compute x{sub Bj}-dependent and Q{sup 2}-dependent nuclear correction factors for iron structure functions which are required in global analyses of free nucleon PDFs. We compare our results with nuclear correction factors from neutrino-nucleus scattering models and correction factors for charged-lepton--iron scattering. We find that, except for very high x{sub Bj}, our correction factors differ in both shape and magnitude from the correction factors of the models and charged-lepton scattering.
Morselli, Lisa L.; Guyon, Aurore; Spiegel, Karine
2011-01-01
Evidence for the role of sleep on metabolic and endocrine function has been reported more than four decades ago. In the past 30 years, the prevalence of obesity and diabetes has greatly increased in industrialized countries, and self-imposed sleep curtailment, now very common, is starting to be recognized as a contributing factor, alongside with increased caloric intake and decreased physical activity. Furthermore, obstructive sleep apnea, a chronic condition characterized by recurrent upper ...
Analyzing Pseudophosphatase Function.
Hinton, Shantá D
2016-01-01
Pseudophosphatases regulate signal transduction cascades, but their mechanisms of action remain enigmatic. Reflecting this mystery, the prototypical pseudophosphatase STYX (phospho-serine-threonine/tyrosine-binding protein) was named with allusion to the river of the dead in Greek mythology to emphasize that these molecules are "dead" phosphatases. Although proteins with STYX domains do not catalyze dephosphorylation, this in no way precludes their having other functions as integral elements of signaling networks. Thus, understanding their roles in signaling pathways may mark them as potential novel drug targets. This chapter outlines common strategies used to characterize the functions of pseudophosphatases, using as an example MK-STYX [mitogen-activated protein kinase (MAPK) phospho-serine-threonine/tyrosine binding], which has been linked to tumorigenesis, apoptosis, and neuronal differentiation. We start with the importance of "restoring" (when possible) phosphatase activity in a pseudophosphatase so that the active mutant may be used as a comparison control throughout immunoprecipitation and mass spectrometry analyses. To this end, we provide protocols for site-directed mutagenesis, mammalian cell transfection, co-immunoprecipitation, phosphatase activity assays, and immunoblotting that we have used to investigate MK-STYX and the active mutant MK-STYXactive. We also highlight the importance of utilizing RNA interference (RNAi) "knockdown" technology to determine a cellular phenotype in various cell lines. Therefore, we outline our protocols for introducing short hairpin RNA (shRNA) expression plasmids into mammalians cells and quantifying knockdown of gene expression with real-time quantitative PCR (qPCR). A combination of cellular, molecular, biochemical, and proteomic techniques has served as powerful tools in identifying novel functions of the pseudophosphatase MK-STYX. Likewise, the information provided here should be a helpful guide to elucidating the
Reducible functional differential equations
Directory of Open Access Journals (Sweden)
S. M. Shah
1985-01-01
Full Text Available This is the first part of a survey on analytic solutions of functional differential equations (FDE. Some classes of FDE that can be reduced to ordinary differential equations are considered since they often provide an insight into the structure of analytic solutions to equations with more general argument deviations. Reducible FDE also find important applications in the study of stability of differential-difference equations and arise in a number of biological models.
Reserve Function in Enterprise
Agnieszka Duraj
2003-01-01
Reserves occupy an important place and play a big part at the enterprise.s financial management system. Problem of reserves also belongs to principle matter of strategic management.they expresses through creating the enterprises competitive position. Reserves fulfill many of various functions in the enterprises. Reserves permit to avoid the risk accompanying the economic activity of each enterprise; they create to the firm a chance of effective development and opportunities of protection of o...
Analyzing Pseudophosphatase Function.
Hinton, Shantá D
2016-01-01
Pseudophosphatases regulate signal transduction cascades, but their mechanisms of action remain enigmatic. Reflecting this mystery, the prototypical pseudophosphatase STYX (phospho-serine-threonine/tyrosine-binding protein) was named with allusion to the river of the dead in Greek mythology to emphasize that these molecules are "dead" phosphatases. Although proteins with STYX domains do not catalyze dephosphorylation, this in no way precludes their having other functions as integral elements of signaling networks. Thus, understanding their roles in signaling pathways may mark them as potential novel drug targets. This chapter outlines common strategies used to characterize the functions of pseudophosphatases, using as an example MK-STYX [mitogen-activated protein kinase (MAPK) phospho-serine-threonine/tyrosine binding], which has been linked to tumorigenesis, apoptosis, and neuronal differentiation. We start with the importance of "restoring" (when possible) phosphatase activity in a pseudophosphatase so that the active mutant may be used as a comparison control throughout immunoprecipitation and mass spectrometry analyses. To this end, we provide protocols for site-directed mutagenesis, mammalian cell transfection, co-immunoprecipitation, phosphatase activity assays, and immunoblotting that we have used to investigate MK-STYX and the active mutant MK-STYXactive. We also highlight the importance of utilizing RNA interference (RNAi) "knockdown" technology to determine a cellular phenotype in various cell lines. Therefore, we outline our protocols for introducing short hairpin RNA (shRNA) expression plasmids into mammalians cells and quantifying knockdown of gene expression with real-time quantitative PCR (qPCR). A combination of cellular, molecular, biochemical, and proteomic techniques has served as powerful tools in identifying novel functions of the pseudophosphatase MK-STYX. Likewise, the information provided here should be a helpful guide to elucidating the
Mitochondria and Endothelial Function
Kluge, Matthew A.; Fetterman, Jessica L.; Vita, Joseph A.
2013-01-01
In contrast to their role in other cell types with higher energy demands, mitochondria in endothelial cells primarily function in signaling cellular responses to environmental cues. This article provides an overview of key aspects of mitochondrial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, ROS production and signaling, calcium homeostasis, regulated cell death, and heme biosynthesis. In each section, we introduce key concepts and then review...
Generalized Network Externality Function
A. Paothong; G.S. Ladde
2012-01-01
In this work, we focus on the development of mathematical modeling of network externality processes. The introduction of the generalized network externality function provides a unified source of a tool for developing and analyzing the planning, policy and performance of the network externality process and network goods/services in a systematic way. This leads to fulfill all existing network externality assumptions as special cases. We study its properties and applications. This study provides...
Choice Probability Generating Functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel L; Bierlaire, Michel
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice...... probabilities, and every CPGF is consistent with an ARUM. We relate CPGF to multivariate extreme value distributions, and review and extend methods for constructing CPGF for applications....
Gunn, Teresa M.
2012-01-01
Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout Mouse Consortium (IKMC) plans to mutate every protein-coding gene, using a combination of gene trapping and gene targeting in embryonic stem cells. Many other groups are performing using the chemical mutagen ethylnitrosourea (ENU) or transpon-based systems to induce mutations, screening ...
Oden, J Tinsley
2010-01-01
The textbook is designed to drive a crash course for beginning graduate students majoring in something besides mathematics, introducing mathematical foundations that lead to classical results in functional analysis. More specifically, Oden and Demkowicz want to prepare students to learn the variational theory of partial differential equations, distributions, and Sobolev spaces and numerical analysis with an emphasis on finite element methods. The 1996 first edition has been used in a rather intensive two-semester course. -Book News, June 2010
LENUS (Irish Health Repository)
Lang, E E
2010-06-01
Vestibular symptoms of vertigo, dizziness and dysequilibrium are common complaints which can be disabling both physically and psychologically. Routine examination of the ear nose and throat and neurological system are often normal in these patients. An accurate history and thorough clinical examination can provide a diagnosis in the majority of patients. However, in a subgroup of patients, vestibular function testing may be invaluable in arriving at a correct diagnosis and ultimately in the optimal treatment of these patients.
Automatic Functional Harmonic Analysis
de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.
2013-01-01
Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of Western tonal harmony that builds on well-known theories of tonal harmony. In contrast to other approaches that remain purely theoretical, we present an implemented system that is evaluated empirica...
Super Fractal Interpolation Functions
G. P. Kapoor; Prasad, Srijanani Anurag
2012-01-01
In the present work, the notion of Super Fractal Interpolation Function (SFIF) is introduced for finer simulation of the objects of the nature or outcomes of scientific experiments that reveal one or more structures embedded in to another. In the construction of SFIF, an IFS is chosen from a pool of several IFS at each level of iteration leading to implementation of the desired randomness and variability in fractal interpolation of the given data. Further, an expository description of our inv...
Green, L
1998-01-01
We often think of law as fulfilling certain social functions; for instance, it is said to guide behaviour, maintain order, settle disputes, and provide benefits and services. In the social sciences, more general claims are also made that law stabilizes the dominant mode of production, promotes economic efficiency, secures patriarchy, and so on. 1 What do these claims mean, and what do they contribute to our understanding of law as a social institution? Those are the questions I want to explor...
Lymphocyte Functions in Microgravity
Pellis, Neal R.; Risin, Diane; Sundaresan, A.; Cooper, D.; Dawson, David L. (Technical Monitor)
1999-01-01
To understand the mechanism of immunity impairment in space it is important to analyze the direct effects of space-related conditions on different lymphocytes functions. Since 1992, we are investigating the effect of modeled and true microgravity (MG) on numerous lymphocyte functions. We had shown that modeled (MMG) and true microgravity inhibit lymphocyte locomotion through type I collagen. Modeled microgravity also suppresses polyclonal and antigen-specific lymphocyte activation. Polyclonal activation of lymphocytes prior to exposure to MMG abrogates the MG-induced inhibition of lymphocyte locomotion. The relationship between activation deficits and the loss of locomotion in MG was investigated using PKC activation by phorbol ester (PMA) and calcium ionophore (ionomycin). Direct activation of PKC by PMA substantially restored the MMG-inhibited lymphocyte locomotion and PHA-induced lymphocyte activation lonomycin by itself did not restore either locomotion or activation of the lymphocytes, indicating that these changes are not related to the impairment in the calcium flux in MMG. Treatment of lymphocytes with PMA before exposure to MMG prevented the loss of locomotion. It was observed that DNA synthesis is not necessary for restoration of locomotion since mitomicin C treated and untreated cells recovered their locomotion to the same level after PKC activation. Our recent data indicate that microgravity may selectively effect the expression of novel Ca2+ independent isoforms of PKC, in particularly PKC sigma and delta. This provides a new insight in understanding of the mechanisms of MG-sensitive cellular functions.
Transporting Functions across Ornaments
Pierre-Evariste, Dagand
2012-01-01
Programming with dependent types is a blessing and a curse. It is a blessing to be able to bake invariants into the definition of data-types: we can finally write correct-by-construction software. However, this extreme accuracy is also a curse: a data-type is the combination of a structuring medium together with a special purpose logic. These domain-specific logics hamper any effort of code reuse among similarly structured data. In this paper, we exorcise our data-types by adapting the notion of ornament to our universe of inductive families. We then show how code reuse can be achieved by ornamenting functions. Using these functional ornament, we capture the relationship between functions such as the addition of natural numbers and the concatenation of lists. With this knowledge, we demonstrate how the implementation of the former informs the implementation of the latter: the user can ask the definition of addition to be lifted to lists and she will only be asked the details necessary to carry on adding lists...
Development of functional foods.
Mitsuoka, Tomotari
2014-01-01
Recent advances in intestinal microbiota research are the background for the appearance of functional foods. Lactic fermentation products are included in the functional foods and classified into 3 groups based on their mechanisms of action: probiotics, prebiotics and biogenics. Probiotics are viable microorganisms, such as lactobacilli and bifidobacteria, that beneficially affect the host by improving the intestinal bacterial balance. Prebiotics are nondigestible food ingredients, such as oligosaccharides and dietary fiber, that beneficially affect the host by selectively stimulating the growth or activities of beneficial intestinal bacteria in the colon and thus improve the health of the hosts. Biogenics are biologically active peptides, including immunopotentiators (biological response modifier: BRM), plant flavonoids, etc. They act directly or indirectly through modulation of intestinal microbiota on the health of the hosts. Thus, functional foods enhance bioregulation such as stresses, appetite and absorption; biodefence, such as immunity and suppression of allergies; prevent diseases, including diarrhea, constipation, cancer, cholesterolemia and diabetes; and suppress aging through immunostimulation as well as suppression of mutagenesis, carcinogenesis, oxidation processes, intestinal putrefaction, and cholesterolemia. PMID:25032085
Functional magnetic resonance imaging.
Buchbinder, Bradley R
2016-01-01
Functional magnetic resonance imaging (fMRI) maps the spatiotemporal distribution of neural activity in the brain under varying cognitive conditions. Since its inception in 1991, blood oxygen level-dependent (BOLD) fMRI has rapidly become a vital methodology in basic and applied neuroscience research. In the clinical realm, it has become an established tool for presurgical functional brain mapping. This chapter has three principal aims. First, we review key physiologic, biophysical, and methodologic principles that underlie BOLD fMRI, regardless of its particular area of application. These principles inform a nuanced interpretation of the BOLD fMRI signal, along with its neurophysiologic significance and pitfalls. Second, we illustrate the clinical application of task-based fMRI to presurgical motor, language, and memory mapping in patients with lesions near eloquent brain areas. Integration of BOLD fMRI and diffusion tensor white-matter tractography provides a road map for presurgical planning and intraoperative navigation that helps to maximize the extent of lesion resection while minimizing the risk of postoperative neurologic deficits. Finally, we highlight several basic principles of resting-state fMRI and its emerging translational clinical applications. Resting-state fMRI represents an important paradigm shift, focusing attention on functional connectivity within intrinsic cognitive networks. PMID:27432660
[Visuospatial functions and prematurity].
Miranda-Herrero, M C; Pascual-Pascual, S I; Barredo-Valderrama, E; Vazquez-Lopez, M; de Castro-De Castro, P
2014-11-01
Visuospatial functions are very important in learning process and development of abstract thought during childhood. Several studies show that preterm and low birth weight infants obtain lower scores in test that assess cognitive functions, specially in the first year of life. These differences are attenuated over time, but a developmental delay that affects working memory and visuospatial process still persists. It is unclear what factors are involved in development of these functions, and pre- or perinatal factors may interfere with the proper conduct of the same, but have been described anatomical and physiological differences between the preterm and term brain that could explain somewhere in these alterations. The different selective vulnerability to hypoxia between immature brain in which preoligodendrocytes and subplate neurons predominate, and mature brain, determine differences in the pattern of injury from hypoxia with greater involvement of the periventricular white matter in preterm children. This lesional pattern leaves to a dysfunction in attentional and visuospatial process, due to the increased vulnerability of the regions involved in the dorsal pathway of visual processing. PMID:25342055
Nicotinamide and neurocognitive function.
Rennie, George; Chen, Andrew C; Dhillon, Haryana; Vardy, Janette; Damian, Diona L
2015-07-01
Nicotinamide, or vitamin B3, is a precursor of nicotinamide adenine dinucleotide (NAD(+)) and is involved in a multitude of intra- and inter-cellular processes, which regulate some of the cell's metabolic, stress, and immune responses to physiological or pathological signals. As a precursor of NAD(+), which is a key coenzyme in the production of adenosine triphosphate or cellular energy, nicotinamide has been investigated for potential neuroprotective effects in cellular, animal, and human studies. Objectives We aimed to summarize the current evidence on the effect of dietary and supplemental nicotinamide on cognitive function. Methods A literature review was conducted on the effects of nicotinamide and its derivatives as a preventive and therapeutic agent for disorders of neurocognitive function. Specific conditions examined include age-related cognitive decline, Alzheimer's disease, Parkinson's disease, and ischaemic and traumatic brain injury. Results Data from animal and human interventional studies and epidemiological research suggests that nicotinamide may be beneficial in preserving and enhancing neurocognitive function. Discussion Nicotinamide is non-toxic, inexpensive and widely available, and interventional studies in humans, using supplemental doses of nicotinamide, are now warranted. PMID:24559077
Composing decoherence functionals
Boes, Paul
2016-01-01
Quantum Measure Theory (QMT) is a generalization of quantum theory where physical predictions are computed from a matrix known as decoherence functional (DF). Previous works have noted that, in its original formulation, QMT exhibits a problem with composability, since the composition of two decoherence functionals is, in general, not a valid decoherence functional. This does not occur when the DFs in question happen to be positive semidefinite (a condition known as strong positivity). In this paper, we study the concept of composability of DFs and its consequences for QMT. First, using the notion of composability, we settle an old problem in QMT regarding the definition of decoherent histories. Then we show that the problem of composability is much deeper than originally envisaged, since, for any $n$, there exists a DF that can co-exist with $n-1$ copies of itself, but not with $n$. Finally, we prove that the set of strongly positive DFs cannot be enlarged while remaining closed under composition. Furthermore...
A CLASS OF FUNCTIONAL EQUATION AND FRACTAL INTERPOLATION FUNCTIONS
Institute of Scientific and Technical Information of China (English)
ShaZhen
1999-01-01
A new class of functional equation in C0(I) is investigated. It is proved that some class of FIF satisfies the functional equation. Another functional equation is constructed. Theirsolutions can approximate FIF arbitrarily. And a new approximate estimate between FIF andinterpolated function is given.
Kidney function decline and physical function in women
Lin, Julie; Curhan, Gary C.
2008-01-01
Background. Cross-sectional analyses of kidney function and physical function have identified profound quality of life impairments in people with advanced kidney dysfunction. No data are currently available, however, on how kidney function decline may be associated with physical function.
[Functional pathophysiology of consciousness].
Jellinger, Kurt A
2009-01-01
Consciousness (Latin conscientia "moral conscience"), according to the English philosopher John Locke (1632-1704) [103], is the awareness of all that occurs in the mind of a person, whereas the American philosopher John Searle (2000) defined it as "inner qualitative, subjective states and processes of awareness". In modern science it is defined as a continuous state of full awareness of the Self and one's relationship to the external and internal environment, describing the degree of wakefulness in which an organism recognizes stimuli. This widely discussed biological term for complex neuronal processes that allow an individuum to recognize itself and its environment and to act accordingly, has been and still is the subject of much research in philosophy and natural/neuroscience. Its definition is often used for awareness and recognition, too. While the Egyptians in the papyrus Edwin Smith already recognized the brain as the seat of consciousness, René Descartes (1644 [36]) believed its special structure should be "a small gland in the middle", but the anatomical structures and physiological processes involved in consciousness were elucidated only in the middle of the 20th century. Neuronal substrates include several functional networks that are hierarchically organized and cooperate functionally. The lowest level is the mesencephalic formatio reticularis and its projections to the thalamus that were identified als ascending reticular system (ARAS) by the classical experiments of Moruzzi and Magoun, whereas later analyses of patients with impaired consciousness provided further insights. The mesencephalic ARAS as motor of the function of higher structures projects 1. via the reticular thalamus diffusely to the cortex, 2. via hypothalamus to the basal forebrain and limbic system, and 3. to the medial raphe of the brainstem and locus coeruleus and their diffuse cortical projections. The reticular system is stimulated directly and indirectly via numerous collaterals
[Functional pathophysiology of consciousness].
Jellinger, Kurt A
2009-01-01
Consciousness (Latin conscientia "moral conscience"), according to the English philosopher John Locke (1632-1704) [103], is the awareness of all that occurs in the mind of a person, whereas the American philosopher John Searle (2000) defined it as "inner qualitative, subjective states and processes of awareness". In modern science it is defined as a continuous state of full awareness of the Self and one's relationship to the external and internal environment, describing the degree of wakefulness in which an organism recognizes stimuli. This widely discussed biological term for complex neuronal processes that allow an individuum to recognize itself and its environment and to act accordingly, has been and still is the subject of much research in philosophy and natural/neuroscience. Its definition is often used for awareness and recognition, too. While the Egyptians in the papyrus Edwin Smith already recognized the brain as the seat of consciousness, René Descartes (1644 [36]) believed its special structure should be "a small gland in the middle", but the anatomical structures and physiological processes involved in consciousness were elucidated only in the middle of the 20th century. Neuronal substrates include several functional networks that are hierarchically organized and cooperate functionally. The lowest level is the mesencephalic formatio reticularis and its projections to the thalamus that were identified als ascending reticular system (ARAS) by the classical experiments of Moruzzi and Magoun, whereas later analyses of patients with impaired consciousness provided further insights. The mesencephalic ARAS as motor of the function of higher structures projects 1. via the reticular thalamus diffusely to the cortex, 2. via hypothalamus to the basal forebrain and limbic system, and 3. to the medial raphe of the brainstem and locus coeruleus and their diffuse cortical projections. The reticular system is stimulated directly and indirectly via numerous collaterals
Collision-resistant hash function based on composition of functions
Ndoundam, Rene
2011-01-01
cryptographic hash function is a deterministic procedure that compresses an arbitrary block of numerical data and returns a fixed-size bit string. There exist many hash functions: MD5, HAVAL, SHA, ... It was reported that these hash functions are not longer secure. Our work is focused in the construction of a new hash function based on composition of functions. The construction used the NP-completeness of Three-dimensional contingency tables and the relaxation of the constraint that a hash function should also be a compression function.
Strange functions in real analysis
Kharazishvili, AB
2005-01-01
Weierstrass and Blancmange nowhere differentiable functions, Lebesgue integrable functions with everywhere divergent Fourier series, and various nonintegrable Lebesgue measurable functions. While dubbed strange or "pathological," these functions are ubiquitous throughout mathematics and play an important role in analysis, not only as counterexamples of seemingly true and natural statements, but also to stimulate and inspire the further development of real analysis.Strange Functions in Real Analysis explores a number of important examples and constructions of pathological functions. After introducing the basic concepts, the author begins with Cantor and Peano-type functions, then moves to functions whose constructions require essentially noneffective methods. These include functions without the Baire property, functions associated with a Hamel basis of the real line, and Sierpinski-Zygmund functions that are discontinuous on each subset of the real line having the cardinality continuum. Finally, he considers e...
Log-supermodular functions, functional clones and counting CSPs
Bulatov, Andrei A; Goldberg, Leslie Ann; Jerrum, Mark
2011-01-01
Motivated by a desire to understand the computational complexity of counting constraint satisfaction problems (counting CSPs), particularly the complexity of approximation, we study functional clones of functions on the Boolean domain, which are analogous to the familiar relational clones constituting Post's lattice. One of these clones is the collection of log-supermodular (lsm) functions, which turns out to play a significant role in classifying counting CSPs. In our study, we assume that non-negative unary functions (weights) are available. Given this, we prove that there are no functional clones lying strictly between the clone of lsm functions and the total clone (containing all functions). Thus, any counting CSP that contains a single non-lsm function is computationally as hard as any problem in #P. Furthermore, any non-trivial functional clone (in a sense that will be made precise below) contains the binary function "implies". As a consequence, all non-trivial counting CSPs (with non-negative unary wei...
Indefinite theta functions and black hole partition functions
International Nuclear Information System (INIS)
We explore various aspects of supersymmetric black hole partition functions in four-dimensional toroidally compactified heterotic string theory. These functions suffer from divergences owing to the hyperbolic nature of the charge lattice in this theory, which prevents them from having well-defined modular transformation properties. In order to rectify this, we regularize these functions by converting the divergent series into indefinite theta functions, thereby obtaining fully regulated single-centered black hole partitions functions
Indefinite theta functions and black hole partition functions
Energy Technology Data Exchange (ETDEWEB)
Cardoso, Gabriel Lopes; Cirafici, Michele [Center for Mathematical Analysis, Geometry, and Dynamical Systems,Departamento de Matemática and LARSyS, Instituto Superior Técnico,1049-001 Lisboa (Portugal); Jorge, Rogério [Instituto Superior Técnico,1049-001 Lisboa (Portugal); Nampuri, Suresh [Laboratoire de Physique Théorique, École Normale Supérieure,24 rue Lhomond, 75231 Paris Cedex 05 (France)
2014-02-05
We explore various aspects of supersymmetric black hole partition functions in four-dimensional toroidally compactified heterotic string theory. These functions suffer from divergences owing to the hyperbolic nature of the charge lattice in this theory, which prevents them from having well-defined modular transformation properties. In order to rectify this, we regularize these functions by converting the divergent series into indefinite theta functions, thereby obtaining fully regulated single-centered black hole partitions functions.
Bioinspired, functional nanoscale materials
Jun, In-Kook
Functional nanomaterials in nature exhibit many unique functions and optical and mechanical properties. Examples of this include the dry adhesion of a gecko's foot, the reduced drag on a shark's skin, the high strength and toughness of nacre, and the superhydrophobic self-cleaning of a lotus leaf. This dissertation is devoted to creating unique and enhanced properties by mimicking such functional materials. We have developed a novel self-pumping membrane, which does not require an applied voltage. The self-pumping membrane harvests chemical energy from a surrounding fluid and uses it for accelerated mass transport across the membrane. A device such as this has promising applications in implantable or remotely operating autonomous devices and membrane-based purification systems. Reproducible and highly active surface enhanced Raman scattering (SERS) substrates were developed using a bottom-up self-assembly technology. With their high sensitivity and good reproducibility, the developed nanostructures (gold nanoparticle and nanohole arrays) as SERS substrates are very promising for applications such as ultra-sensitive detectors for chemicals and reproducible sensors for chemical and biological molecules. Binary colloidal crystals were created using a simple, fast, and scalable spin-coating technology. Although further investigation of the procedure is needed to improve the ordering of particles in the individual layers, the developed assembly technology has a promising outlook in applications such as optical integrated circuits and high-speed optical computing. Inorganic-organic nanocomposites were realized by assembling synthesized gibbsite nanoplatelets using the electrophoretic deposition and infiltration of a monomer followed by polymerization. Via surface modifications of gibbsite nanoplatelets, nanocomposites were further reinforced with covalent linkages between the inorganic platelets and organic matrix.
Housset, Chantal; Chrétien, Yues; Debray, Dominique; Chignard, Nicolas
2016-01-01
The gallbladder stores and concentrates bile between meals. Gallbladder motor function is regulated by bile acids via the membrane bile acid receptor, TGR5, and by neurohormonal signals linked to digestion, for example, cholecystokinin and FGF15/19 intestinal hormones, which trigger gallbladder emptying and refilling, respectively. The cycle of gallbladder filling and emptying controls the flow of bile into the intestine and thereby the enterohepatic circulation of bile acids. The gallbladder also largely contributes to the regulation of bile composition by unique absorptive and secretory capacities. The gallbladder epithelium secretes bicarbonate and mucins, which both provide cytoprotection against bile acids. The reversal of fluid transport from absorption to secretion occurs together with bicarbonate secretion after feeding, predominantly in response to an adenosine 3',5'-cyclic monophosphate (cAMP)-dependent pathway triggered by neurohormonal factors, such as vasoactive intestinal peptide. Mucin secretion in the gallbladder is stimulated predominantly by calcium-dependent pathways that are activated by ATP present in bile, and bile acids. The gallbladder epithelium has the capacity to absorb cholesterol and provides a cholecystohepatic shunt pathway for bile acids. Changes in gallbladder motor function not only can contribute to gallstone disease, but also subserve protective functions in multiple pathological settings through the sequestration of bile acids and changes in the bile acid composition. Cholecystectomy increases the enterohepatic recirculation rates of bile acids leading to metabolic effects and an increased risk of nonalcoholic fatty liver disease, cirrhosis, and small-intestine carcinoid, independently of cholelithiasis. Among subjects with gallstones, cholecystectomy remains a priority in those at risk of gallbladder cancer, while others could benefit from gallbladder-preserving strategies. © 2016 American Physiological Society. Compr Physiol
Perioperative functional residual capacity.
Wahba, R W
1991-04-01
The literature dealing with the magnitude, mechanism and effects of reduced FRC in the perioperative period is reviewed. During general anaesthesia FRC is reduced by approximately 20%. The reduction is greater in the obese and in patients with COPD. The most likely mechanism is the loss of inspiratory muscle tone of the muscles acting on the rib cage. Gas trapping is an additional mechanism. Lung compliance decreases and airways resistance increases, in large part, due to decreased FRC. The larynx is displaced anteriorly and elongated, making laryngoscopy and intubation more difficult. The change in FRC creates or increases intrapulmonary shunt and areas of low ventilation to perfusion. This is due to the occurrence of compression atelectasis, and to regional changes in mechanics and airway closure which tend to reduce ventilation to dependent lung zones which are still well perfused. Abdominal and thoracic operations tend to increase shunting further. Large tidal volume but not PEEP will improve oxygenation, although both increase FRC. Both FRC and vital capacity are reduced following abdominal and thoracic surgery in a predictable pattern. The mechanism is the combined effect of incisional pain and reflex dysfunction of the diaphragm. Additional effects of thoracic surgery include pleural effusion, cooling of the phrenic nerve and mediastinal widening. Postoperative hypoxaemia is a function of reduced FRC and airway closure. There is no real difference among the various methods of active lung expansion in terms of the speed of restoration of lung function, or in preventing postoperative atelectasis/pneumonia. Epidural analgesia does not influence the rate of recovery of lung function, nor does it prevent atelectasis/pneumonia. PMID:2036700
Aumasson, Jean-Philippe; Phan, Raphael; Henzen, Luca
2014-01-01
This is a comprehensive description of the cryptographic hash function BLAKE, one of the five final contenders in the NIST SHA3 competition, and of BLAKE2, an improved version popular among developers. It describes how BLAKE was designed and why BLAKE2 was developed, and it offers guidelines on implementing and using BLAKE, with a focus on software implementation. In the first two chapters, the authors offer a short introduction to cryptographic hashing, the SHA3 competition, and BLAKE. They review applications of cryptographic hashing, they describe some basic notions such as security de
Hathaway, Dan
2014-01-01
For each $a \\in {^\\omega \\omega}$, we define a Baire class one function $f_a : {^\\omega \\omega} \\to {^\\omega \\omega}$ which encodes $a$ in a certain sense. We show that for each Borel $g : {^\\omega \\omega} \\to {^\\omega \\omega}$, $f_a \\cap g = \\emptyset$ implies $a \\in \\Delta^1_1(c)$ where $c$ is any code for $g$. We generalize this theorem for $g$ in a larger pointclass $\\Gamma$. Specifically, when $\\Gamma = \\mathbf{\\Delta}^1_2$, $a \\in L[c]$. Also for all $n \\in \\omega$, when $\\Gamma = \\math...
Gelfand, I M; Shnol, E E
2002-01-01
The second in a series of systematic studies by a celebrated mathematician I. M. Gelfand and colleagues, this volume presents students with a well-illustrated sequence of problems and exercises designed to illuminate the properties of functions and graphs. Since readers do not have the benefit of a blackboard on which a teacher constructs a graph, the authors abandoned the customary use of diagrams in which only the final form of the graph appears; instead, the book's margins feature step-by-step diagrams for the complete construction of each graph. The first part of the book employs simple fu
International Nuclear Information System (INIS)
Effective and rigorous controls over highly enriched uranium and plutonium, the essential ingredients of nuclear weapons, are critical if we are to reduce nuclear arms, bring a halt to nuclear proliferation, and to avoid large-scale nuclear violence. Currently an unfortunate and simplistic 'one-size-fits-all' attitude about nuclear security is prominent. We have identified seven basic and decidedly distinct nuclear husbandry functions. The analysis leads to some predictions for effective nuclear arms control and nonproliferation, including the idea that domestic nuclear security and safeguards personnel, hardware, approaches, and auditing techniques are not automatically applicable to international arms control efforts. (author)
Matrix string partition function
Kostov, Ivan K; Kostov, Ivan K.; Vanhove, Pierre
1998-01-01
We evaluate quasiclassically the Ramond partition function of Euclidean D=10 U(N) super Yang-Mills theory reduced to a two-dimensional torus. The result can be interpreted in terms of free strings wrapping the space-time torus, as expected from the point of view of Matrix string theory. We demonstrate that, when extrapolated to the ultraviolet limit (small area of the torus), the quasiclassical expressions reproduce exactly the recently obtained expression for the partition of the completely reduced SYM theory, including the overall numerical factor. This is an evidence that our quasiclassical calculation might be exact.
Choice probability generating functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2013-01-01
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice...... probabilities, and every CPGF is consistent with an ARUM. We relate CPGF to multivariate extreme value distributions, and review and extend methods for constructing CPGF for applications. The choice probabilities of any ARUM may be approximated by a cross-nested logit model. The results for ARUM are extended...
Indicators and their functions
DEFF Research Database (Denmark)
Gudmundsson, Henrik; Joumard, Robert; Aschemann, Ralf
2010-01-01
indicators? How can several indicators be jointly considered? And how can indicators be used in planning and decision making? Firstly we provide definition of 'indicator of environmental sustainability in transport'. The functions, strengths and weaknesses of indicators as measurement tools, and as decision...... in transport, in terms of measurement, monitoring and management. The methods and the criteria are exemplified for seven chains of causality. Methods for a comprehensive joint consideration of environmentally sustainable indicators are analyzed and evaluated. They concerned aggregated or composite indicators...
Design of functional metalloproteins.
Lu, Yi; Yeung, Natasha; Sieracki, Nathan; Marshall, Nicholas M
2009-08-13
Metalloproteins catalyse some of the most complex and important processes in nature, such as photosynthesis and water oxidation. An ultimate test of our knowledge of how metalloproteins work is to design new metalloproteins. Doing so not only can reveal hidden structural features that may be missing from studies of native metalloproteins and their variants, but also can result in new metalloenzymes for biotechnological and pharmaceutical applications. Although it is much more challenging to design metalloproteins than non-metalloproteins, much progress has been made in this area, particularly in functional design, owing to recent advances in areas such as computational and structural biology.
Bayes multiple decision functions.
Wu, Wensong; Peña, Edsel A
2013-01-01
This paper deals with the problem of simultaneously making many (M) binary decisions based on one realization of a random data matrix X. M is typically large and X will usually have M rows associated with each of the M decisions to make, but for each row the data may be low dimensional. Such problems arise in many practical areas such as the biological and medical sciences, where the available dataset is from microarrays or other high-throughput technology and with the goal being to decide which among of many genes are relevant with respect to some phenotype of interest; in the engineering and reliability sciences; in astronomy; in education; and in business. A Bayesian decision-theoretic approach to this problem is implemented with the overall loss function being a cost-weighted linear combination of Type I and Type II loss functions. The class of loss functions considered allows for use of the false discovery rate (FDR), false nondiscovery rate (FNR), and missed discovery rate (MDR) in assessing the quality of decision. Through this Bayesian paradigm, the Bayes multiple decision function (BMDF) is derived and an efficient algorithm to obtain the optimal Bayes action is described. In contrast to many works in the literature where the rows of the matrix X are assumed to be stochastically independent, we allow a dependent data structure with the associations obtained through a class of frailty-induced Archimedean copulas. In particular, non-Gaussian dependent data structure, which is typical with failure-time data, can be entertained. The numerical implementation of the determination of the Bayes optimal action is facilitated through sequential Monte Carlo techniques. The theory developed could also be extended to the problem of multiple hypotheses testing, multiple classification and prediction, and high-dimensional variable selection. The proposed procedure is illustrated for the simple versus simple hypotheses setting and for the composite hypotheses setting
Functional and Operatorial Statistics
Dabo-niang, Sophie
2008-01-01
An increasing number of statistical problems and methods involve infinite-dimensional aspects. This is due to the progress of technologies which allow us to store more and more information while modern instruments are able to collect data much more effectively due to their increasingly sophisticated design. This evolution directly concerns statisticians, who have to propose new methodologies while taking into account such high-dimensional data (e.g. continuous processes, functional data, etc.). The numerous applications (micro-arrays, paleo- ecological data, radar waveforms, spectrometric curv
Some integrals involving Bessel functions
Glasser, M. Lawrence; Montaldi, Emilio
1993-01-01
A number of new definite integrals involving Bessel functions are presented. These have been derived by finding new integral representations for the product of two Bessel functions of different order and argument in terms of the generalized hypergeometric function with subsequent reduction to special cases. Connection is made with Weber's second exponential integral and Laplace transforms of products of three Bessel functions.
Functional Foods for Women's Health.
Lindeman, Alice K.
2002-01-01
Describes functional foods for women's health (foods or food ingredients that provide health benefits beyond basic nutrition), explaining that both whole and modified foods can be included as functional foods. The paper discusses the history, regulation, and promotion of functional foods; consumer interest in functional foods; how to incorporate…
Some Properties of Bent Functions
Institute of Scientific and Technical Information of China (English)
Ying Zhao
2007-01-01
First, this paper discusses and sums up some properties of a pair of functions p(x), q(x) that makes (y + 1)p(x) + yq(x) into a bent function. Then it discusses the properties of bent functions. Also, the upper and lower bounds of the number of bent functions on GF(2)2k are discussed.
A Primer on Functional Analysis
Yoman, Jerome
2008-01-01
This article presents principles and basic steps for practitioners to complete a functional analysis of client behavior. The emphasis is on application of functional analysis to adult mental health clients. The article includes a detailed flow chart containing all major functional diagnoses and behavioral interventions, with functional assessment…
Pfaffian and Determinantal Tau Functions
van de Leur, Johan W.; Orlov, Alexander Yu.
2015-11-01
Adler, Shiota and van Moerbeke observed that a tau function of the Pfaff lattice is a square root of a tau function of the Toda lattice hierarchy of Ueno and Takasaki. In this paper, we give a representation theoretical explanation for this phenomenon. We consider 2-BKP and two-component 2-KP tau functions. We shall show that a square of a BKP tau function is equal to a certain two-component KP tau function and a square of a 2-BKP tau function is equal to a certain two-component 2-KP tau function.
Hypertension and cognitive function.
Paglieri, Cristina; Bisbocci, Daniela; Caserta, Mimma; Rabbia, Franco; Bertello, Chiara; Canadè, Antonella; Veglio, Franco
2008-11-01
Arterial hypertension, cerebrovascular disease, and dementia are related pathologies. This paper has reviewed comparatively the incidence of arterial hypertension and adult-onset dementia disorders. Hypertension is associated with cerebrovascular disease, which is in turn associated with dementia. It is the most important modifiable risk factor for stroke, which is a recognized cause of vascular dementia. In terms of pathophysiology of hypertensive brain damage, several hypotheses were developed, such as that vascular alterations induced by hypertension can induce lacunar or cortical infarcts and leucoaraiosis, that hypertension is responsible for cerebrovascular disease and acts into the contest of a pre-existing subclinic Alzheimer's disease (AD), that hypertension determines neurobiologic alterations (such as beta-amyloid accumulation) resulting in neuropathologic damage, and that aging and cerebrovascular risk factors act together to cause cerebral capillary degeneration, mitochondrial disruption, reduced glucose oxidation, and reduced ATP synthesis. The consequence of these alterations are neuronal death and dementia. Macroscopic results of these mechanisms are the so-called white matter lesions (WML), the significance of which is analyzed. Increasing clinical evidence suggests a close relationship between the reduction of elevated blood pressure and countering of both vascular dementia and AD. Antihypertensive treatment probably influences cognitive performances and prevents cognitive function alterations and the development of dementia. It is therefore important to evaluate as soon as possible cognitive functions of hypertensive patients. PMID:19021021
Chitosan functional properties.
Shepherd, R; Reader, S; Falshaw, A
1997-06-01
Chitosan is a partially deacetylated polymer of N-acetyl glucosamine. It is essentially a natural, water-soluble, derivative of cellulose with unique properties. Chitosan is usually prepared from chitin (2 acetamido-2-deoxy beta-1,4-D-glucan) and chitin has been found in a wide range of natural sources (crustaceans, fungi, insects, annelids, molluscs, coelenterata etc.) However chitosan is only manufactured from crustaceans (crab and crayfish) primarily because a large amount of the crustacean exoskeleton is available as a by product of food processing. Squid pens (a waste byproduct of New Zealand squid processing) are a novel, renewable source of chitin and chitosan. Squid pens are currently regarded as waste and so the raw material is relatively cheap. This study was intended to assess the functional properties of squid pen chitosan. Chitosan was extracted from squid pens and assessed for composition, rheology, flocculation, film formation and antimicrobial properties. Crustacean chitosans were also assessed for comparison. Squid chitosan was colourless, had a low ash content and had significantly improved thickening and suspending properties. The flocculation capacity of squid chitosan was low in comparison with the crustacean sourced chitosans. However it should be possible to increase the flocculation capacity of squid pen chitosan by decreasing the degree of acetylation. Films made with squid chitosan were more elastic than crustacean chitosan with improved functional properties. This high quality chitosan could prove particularly suitable for medical/analytical applications.
Directory of Open Access Journals (Sweden)
SCARLAT Razvan
2016-05-01
Full Text Available The functional clothing represents a sustainable development direction of in the field of technical textiles, a bridge between various activity domains, a solution to user’s complex requirements. The research and development potential in the field is supported by the new fibers/ yarns generation, the new technologies and the market niches, as well. Protective clothing is now a major part of textile classified under technical textile. Protective clothing refers to the garment and other fabric related items designed to protect the wearer from harsh environmental effects that results in injuries or death. The innovation, as a result of convergence processing technologies, consumer demands and what is viable on the market, defines the personal protective equipment field. In this article, we present the work of an ESD protective clothing development. Therefore, it has been applied a modern knitting technology, on 7E and 12E STOLL machines, using cotton and wool yarns as base yarn and conductive yarns for plaiting structures. Also, the optimal parameters establishment and the functional requirements are aspects of the research activity performed. The experimental models have been conducted in order to demonstrate the design concept used and choosing the optimal variant. The characterization of the developed experimental variants took into account the evaluation of physico-mechanical and electrical characteristics. From the electrical point of view, the variants have been mainly evaluated through “point to point” method in terms of electrical isolation efficiency dimensional changes analysis.
Functionalism and consciousness.
Shoemaker, S
1993-01-01
It is widely held that a mental state and the subject's introspective belief about it are always 'distinct existences' and only contingently connected. This suggests that for each sort of mental state there could be a creature that is introspectively 'blind' with respect to states of that sort, meaning that while it is capable of having such states, and of conceiving of itself as having them, it is totally without introspective access to its states of that sort. It is argued here that introspective blindness with respect to many sorts of mental states, in particular beliefs and sensory states, is not a possibility, because it is incompatible with requirements of rationality that are internal to the functional roles that are constitutive of these states. Introspective accessibility is essential to the functional roles of such mental states when the conceptual and cognitive resources of the subject of those states are sufficiently rich to make beliefs and thoughts about them a possibility. This is a version of the view that such states are necessarily self-intimating and is incompatible with the perceptual model of introspection favoured by some functionalists as well as by many non-functionalists.
Construction of bent functions from near-bent functions
DEFF Research Database (Denmark)
Leander, Gregor; McGuire, G.
2009-01-01
We give a construction of bent functions in dimension 2m from near-bent functions in dimension 2m - 1. in particular, we give the first ever examples of non-weakly-normal bent functions in dimensions 10 and 12, which demonstrates the significance of our construction.......We give a construction of bent functions in dimension 2m from near-bent functions in dimension 2m - 1. in particular, we give the first ever examples of non-weakly-normal bent functions in dimensions 10 and 12, which demonstrates the significance of our construction....
Nag, Nagendra; Goldman, Lee M.; Balasubramanian, Sreeram; Sastri, Suri
2013-06-01
The requirements for modern aircraft are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the physical properties of optically transparent materials currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows held in weight bearing frames. Novel material systems will have to be developed which combine different materials (e.g. ductile metals with transparent ceramics) into structures that combine transparency with structural integrity. Surmet's demonstrated ability to produce novel transparent ceramic/metal structures will allow us to produce such structures in the types of conformal shapes required for future aircraft applications. Furthermore, the ability to incorporate transparencies into such structures also holds out the promise of creating multi-functional windows which provide a broad range of capabilities that might include RF antennas and de-icing in addition to transparency. Recent results in this area will be presented.
International Nuclear Information System (INIS)
A short revision of thyroid physiology is done. The radioisotopes of common use in thyroid investigation and the choice of the most appropriated ones are discussed. A table showing radioisotopes frequently used in this study, with their main characteristics is presented. Among several isotopic assays in thyroid propaedeutics, those that refer to the function study, topographic studies and tests 'in vitro' are pointed out. Exploration methods 'in vivo' are treated, such as: thyroid uptake; urinary excretion; thyroid scintigraphy, with scintigraphic imagings; stimulation test by TSH; suppression test; pbi; clearance test with perchlorate; iodine deficiency test and thyroid study with technetium. 'In vitro' proofs like triiodothyronine (T3) and thyroxine (T4) assays, as well as free thyroxine index, are treated. At last, the therapeutics by Iodine 131 is commented and emphasis is given to its application on the treatment of hyperthyroidism and thyroid carcinoma
Directory of Open Access Journals (Sweden)
Naito Yuji
2006-06-01
Full Text Available Abstract Appropriate nutrition is an essential prerequisite for effective improvement of athletic performance, conditioning, recovery from fatigue after exercise, and avoidance of injury. Nutritional supplements containing carbohydrates, proteins, vitamins, and minerals have been widely used in various sporting fields to provide a boost to the recommended daily allowance. In addition, several natural food components have been found to show physiological effects, and some of them are considered to be useful for promoting exercise performance or for prevention of injury. However, these foods should only be used when there is clear scientific evidence and with understanding of the physiological changes caused by exercise. This article describes various "functional foods" that have been reported to be effective for improving exercise performance or health promotion, along with the relevant physiological changes that occur during exercise.
Thermodynamic Function of Life
Michaelian, K
2009-01-01
Darwinian Theory depicts life as being overwhelmingly consumed by a fight for survival in a hostile environment. However, from a thermodynamic perspective, life is a dynamic, out of equilibrium process, stabilizing and coevolving in concert with its abiotic environment. The living component of the biosphere of greatest mass, the plants and cyanobacteria, are involved in the transpiration of vast amounts of water. Transpiration is part of the global water cycle, and it is this cycle that distinguishes Earth from its life barren neighboring planets, Venus and Mars. The water cycle, including the absorption of sunlight in the biosphere, is by far the greatest entropy producing process occurring on Earth. Life, from this perspective, can therefore be viewed as performing an important thermodynamic function; acting as a dynamic catalyst by aiding process such as the water cycle, hurricanes, and ocean and wind currents to produce entropy. The role of animals in this view is that of unwitting but dedicated servants ...
DEFF Research Database (Denmark)
Bang, Anne Louise
2007-01-01
sensing of fabrics in function. It is proposed that tactile and visual sensing of fabrics is a way to investigate and express emotional utility values. The further purpose is to use experiments with repertory grid models as part of the mapping of the entire research project and also as a basis...... to the establishment of an initial framework for the project it has a focus on how to explore costumers and users emotional experiences with fabrics. The three year research project is based on experimental design research and the textile designer's competences and knowledge. During the research project exploring...... approaches will be developed and carried out with he intention to involve specific stakeholders within an industrial value chain in the design process. More specifically this paper reports on a pilot experiment initiated to explore if repertory grid models could be a way to investigate tactile and visual...
[Iron function and carcinogenesis].
Akatsuka, Shinya; Toyokuni, Shinya
2016-07-01
Though iron is an essential micronutrient for humans, the excess state is acknowledged to be associated with oncogenesis. For example, iron overload in the liver of the patients with hereditary hemocromatosis highly increases the risk of hepatocellular carcinoma. Also, as to asbestos-related mesothelioma, such kinds of asbestos with a higher iron content are considered to be more carcinogenic. Iron is a useful element, which enables fundamental functions for life such as oxygen carrying and electron transport. However, in the situation where organisms are unable to have good control of it, iron turns into a dangerous element which catalyzes generation of reactive oxygen. In this review, I first outline the relationships between iron and cancer in general, then give an explanation about iron-related animal carcinogenesis models.
Integration a functional approach
Bichteler, Klaus
1998-01-01
This book covers Lebesgue integration and its generalizations from Daniell's point of view, modified by the use of seminorms. Integrating functions rather than measuring sets is posited as the main purpose of measure theory. From this point of view Lebesgue's integral can be had as a rather straightforward, even simplistic, extension of Riemann's integral; and its aims, definitions, and procedures can be motivated at an elementary level. The notion of measurability, for example, is suggested by Littlewood's observations rather than being conveyed authoritatively through definitions of (sigma)-algebras and good-cut-conditions, the latter of which are hard to justify and thus appear mysterious, even nettlesome, to the beginner. The approach taken provides the additional benefit of cutting the labor in half. The use of seminorms, ubiquitous in modern analysis, speeds things up even further. The book is intended for the reader who has some experience with proofs, a beginning graduate student for example. It might...
Physically Functional Materials
DEFF Research Database (Denmark)
2002-01-01
of information (holographic data storage), nonlinear optics (NLO), as photoconductors, photonic band-gap materials, electrically conducting materials, electroluminescent materials, piezo-electric materials, pyroelectric materials, magnetic materials, ferromagnetic materials, ferroelectric materials...... acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techniques. Materials, e.g., thin films, comprising such compounds may be used for optical storage......, photorefractive materials, or materials in which light-induced conformational changes can be produced. Optical anisotropy may reversibly be generated with polarized laser light whereby a hologram is formed. First order diffraction efficiencies of up to around 80% have been obtained....
Triebel, Hans
1983-01-01
The book deals with the two scales Bsp,q and Fsp,q of spaces of distributions, where -8functions, Fourier multipliers and interpolation assertions. These topics are treated in Chapter 2, which is the heart
Heart function and hemodynamics
Institute of Scientific and Technical Information of China (English)
1993-01-01
930469 The effects of different ventricular pac-ing rates on cardiac hemodynamics and theirclinical significance.WEI Meng(魏盟),et al.Zhongshan Hosp,Shanghai Med Univ,Shanghai,200032.Shanghai Med J 1993;16(3):125—126.Changes of hemodynamics were investigated in26 patients at ventricular pacing rate of 60 to120,and 160 bpm.Effects of increasing ventricu-lar pacing rate on EF which were determined bygated blood pool scintigraphy were also studiedin another 11 patients.It is concluded that:1)inpatients with normal cardiac function as well asmost patients with cardiac insufficiency,the rela-tion of CO with increasing pacing rate can be il-
Exercise and autonomic function.
Goldsmith, R L; Bloomfield, D M; Rosenwinkel, E T
2000-03-01
The complex interplay between the dichotomous subdivisions of the autonomic nervous system establishes and maintains a delicately tuned homeostasis in spite of an ever-changing environment. Aerobic exercise training can increase activity of the parasympathetic nervous system and decrease sympathetic activity. Conversely, it is well-documented that cardiac disease is often characterized by attenuated parasympathetic activity and heightened sympathetic tone. A correlation between autonomic disequilibrium and disease has led to the hypothesis that exercise training, as a therapy that restores the autonomic nervous system towards normal function, may be associated with, and possibly responsible for, outcome improvements in various populations. This is merely one of the many benefits that is conferred by chronic exercise training and reviewed in this issue. PMID:10758814
International Nuclear Information System (INIS)
Functional magnetic resonance imaging (fMRI) is a non-invasive method that has become one of the major tools for understanding human brain function and in recent years has also been developed for clinical applications. Changes in hemodynamic signals correspond to changes in neuronal activity with good spatial and temporal resolution in fMRI. Using high-field MR systems and increasingly dedicated statistics and postprocessing, activated brain areas can be detected and superimposed on anatomical images. Currently, fMRI data are often combined in multimodal imaging, e. g. with diffusion tensor imaging (DTI) sequences. This method is helping to further understand the physiology of cognitive brain processes and is also being used in a number of clinical applications. In addition to the blood oxygenation level-dependent (BOLD) signals, this article deals with the construction of fMRI investigations, selection of paradigms and evaluation in the clinical routine. Clinically, this method is mainly used in the planning of brain surgery, analyzing the location of brain tumors in relation to eloquent brain areas and the lateralization of language processing. As the BOLD signal is dependent on the strength of the magnetic field as well as other limitations, an overview of recent developments is given. Increases of magnetic field strength (7 T), available head coils and advances in MRI analytical methods have led to constant improvement in fMRI signals and experimental design. Especially the depiction of eloquent brain regions can be done easily and quickly and has become an essential part of presurgical planning. (orig.)
Pulmonary function in microgravity
Guy, H. J.; Prisk, G. K.; West, J. B.
1992-01-01
We report the successful collection of a large quantity of human resting pulmonary function data on the SLS-1 mission. Preliminary analysis suggests that cardiac stroke volumes are high on orbit, and that an adaptive reduction takes at least several days, and in fact may still be in progress after 9 days on orbit. It also suggests that pulmonary capillary blood volumes are high, and remain high on orbit, but that the pulmonary interstitium is not significantly impacted. The data further suggest that the known large gravitational gradients of lung function have only a modest influence on single breath tests such as the SBN washout. They account for only approximately 25% of the phase III slope of nitrogen, on vital capacity SBN washouts. These gradients are only a moderate source of the cardiogenic oscillations seen in argon (bolus gas) and nitrogen (resident gas), on such tests. They may have a greater role in generating the normal CO2 oscillations, as here the phase relationship to argon and nitrogen reverses in microgravity, at least at mid exhalation in those subjects studied to date. Microgravity may become a useful tool in establishing the nature of the non-gravitational mechanisms that can now be seen to play such a large part in the generation of intra-breath gradients and oscillations of expired gas concentration. Analysis of microgravity multibreath nitrogen washouts, single breath washouts from more physiological pre-inspiratory volumes, both using our existing SLS-1 data, and data from the upcoming D-2 and SLS-2 missions, should be very fruitful in this regard.(ABSTRACT TRUNCATED AT 250 WORDS).
Tamoxifen and ovarian function.
Directory of Open Access Journals (Sweden)
Martine Berliere
Full Text Available BACKGROUND: Some studies suggest that the clinical parameter "amenorrhea" is insufficient to define the menopausal status of women treated with chemotherapy or tamoxifen. In this study, we investigated and compared the ovarian function defined either by clinical or biological parameters in pre-menopausal breast cancer patients treated with tamoxifen administered as adjuvant therapy. MATERIALS AND METHODS: Between 1999 and 2003, 138 premenopausal patients consecutively treated for early breast cancer were included. Sixty-eight received tamoxifen in monotherapy as the only adjuvant systemic treatment (Group I and 70 were treated with tamoxifen after adjuvant chemotherapy (Group II. All patients had a confirmed premenopausal status based on clinical parameters and hormonal values at study entry. They were followed prospectively every 3 months for 3 years: menses data, physical examination and blood tests (LH, FSH, 17-beta-estradiol. Vaginal ultrasonography was carried out every 6 months. After 3 years, prospective evaluation was completed and monitoring of ovarian function was performed as usual in our institution (1x/year. All data were retrospectively evaluated in 2011. RESULTS: Three patients were excluded from the study in group I and 2 were excluded in group II. Patients were divided into 4 subgroups according to clinical data, i.e. menses patterns. These patterns were assessed by questionnaires. a: Regular menses (>10 cycles/year b: Oligomenorrhea (5 to 9 cycles/year c: Severe oligomenorrhea (1 to 4 cycles/year d: Complete amenorrhea Estrogen levels did not appear to have any impact on disease-free survival rates after 3 or 8 years. FSH values were also documented and analyzed. They exhibited the same profile as estradiol values. CONCLUSIONS: Amenorrhea is an insufficient parameter to define menopausal status in patients receiving tamoxifen. Low estradiol levels must be coupled with other biological parameters to characterize endocrine status
Directory of Open Access Journals (Sweden)
K. Vessal
2005-08-01
Full Text Available Introduction & Background: The historical evolution of concepts of the mind has had a tremendous impact on human civilization. Aside from Smith’s surgical papyrus, there exists practically no documentation down to the era of Hippocrates. While in Corpus, the seat of all sensations is put in the brain, there is an amazing regression, for many centuries thereafter notably influenced by Aristotle, to displace it to the heart. This erroneous diversion promulgated in De Anima with minor corrections by Galen, has per-petuated to our time when we say, for example, that we love something with our very hearts or “knowing by heart” when we mean to memorize something. Avicenna challenged many of Aristotle’s ideas in El-monnafs (psychology section of Al Shafa, paving the road for the later European Renaissance. Cartesian choice of pineal body as the seat of soul in the first half of the 7th century was a fundamental departure from brain-soul dichotomy. It was followed by Gall’s pseudo-science, phrenology, as the first attempt of brain mapping in ascribing “mental faculties” to the speculative “organs” of the brain. Brain mapping through Functional Brain Imaging has flourished ex-tensively in the past decades -starting from PET with later substitution by fMRI- as robust tools for interro-gating mysteries of the brain. With a surprising pace of development, Functional Brain Imaging heralds a welcome adjunct to the science of radiology in ex-ploring mind and human behavior. Given the multi-tude of appropriate MRI machines operating across the country, attention to this aspect of imaging can invigorate research in radiology and boost generation of knowledge in this rapidly growing field. Recent advances in MRI fast imaging, fMRI, as well as clini-cal and spectroscopic imaging with present clinical application and future trends are discussed.
Exponential generating functions for the associated Bessel functions
Energy Technology Data Exchange (ETDEWEB)
Fakhri, H [Department of Theoretical Physics and Astrophysics, Physics Faculty, University of Tabriz, PO Box 51666-16471, Tabriz (Iran, Islamic Republic of); Mojaveri, B; Nobary, M A Gomshi [Department of Physics, Faculty of Science, Razi University, Kermanshah (Iran, Islamic Republic of)], E-mail: hfakhri@tabrizu.ac.ir, E-mail: bmojaveri@raziu.ac.ir, E-mail: mnobary@razi.ac.ir
2008-09-26
Similar to the associated Legendre functions, the differential equation for the associated Bessel functions B{sub l,m}(x) is introduced so that its form remains invariant under the transformation l {yields} -l - 1. A Rodrigues formula for the associated Bessel functions as squared integrable solutions in both regions l < 0 and l {>=} 0 is presented. The functions with the same m but with different positive and negative values of l are not independent of each other, while the functions with the same l + m (l - m) but with different values of l and m are independent of each other. So, all the functions B{sub l,m}(x) may be taken into account as the union of the increasing (decreasing) infinite sequences with respect to l. It is shown that two new different types of exponential generating functions are attributed to the associated Bessel functions corresponding to these rearranged sequences.
Exponential generating functions for the associated Bessel functions
Fakhri, H.; Mojaveri, B.; Gomshi Nobary, M. A.
2008-09-01
Similar to the associated Legendre functions, the differential equation for the associated Bessel functions Bl,m(x) is introduced so that its form remains invariant under the transformation l → -l - 1. A Rodrigues formula for the associated Bessel functions as squared integrable solutions in both regions l = 0 is presented. The functions with the same m but with different positive and negative values of l are not independent of each other, while the functions with the same l + m (l - m) but with different values of l and m are independent of each other. So, all the functions Bl,m(x) may be taken into account as the union of the increasing (decreasing) infinite sequences with respect to l. It is shown that two new different types of exponential generating functions are attributed to the associated Bessel functions corresponding to these rearranged sequences.
Lyapunov functionals and stability of stochastic functional differential equations
Shaikhet, Leonid
2013-01-01
Stability conditions for functional differential equations can be obtained using Lyapunov functionals. Lyapunov Functionals and Stability of Stochastic Functional Differential Equations describes the general method of construction of Lyapunov functionals to investigate the stability of differential equations with delays. This work continues and complements the author’s previous book Lyapunov Functionals and Stability of Stochastic Difference Equations, where this method is described for discrete- and continuous-time difference equations. The text begins with a description of the peculiarities of deterministic and stochastic functional differential equations. There follow basic definitions for stability theory of stochastic hereditary systems, and a formal procedure of Lyapunov functionals construction is presented. Stability investigation is conducted for stochastic linear and nonlinear differential equations with constant and distributed delays. The proposed method is used for stability investigation of di...
Applications of Smarandache Function, and Prime and Coprime Functions
Ruiz, Sebastián Martín
2002-01-01
A book for people who love numbers: Smarandache Function applied to perfect numbers, congruences. Also, the Smarandache Prime and Coprime functions in connection with the expressions of the prime numbers.
Generalized -deformed correlation functions as spectral functions of hyperbolic geometry
Bonora, L.; Bytsenko, A. A.; Guimarães, M. E. X.
2014-08-01
We analyze the role of vertex operator algebra and 2d amplitudes from the point of view of the representation theory of infinite-dimensional Lie algebras, MacMahon and Ruelle functions. By definition p-dimensional MacMahon function, with , is the generating function of p-dimensional partitions of integers. These functions can be represented as amplitudes of a two-dimensional c = 1 CFT, and, as such, they can be generalized to . With some abuse of language we call the latter amplitudes generalized MacMahon functions. In this paper we show that generalized p-dimensional MacMahon functions can be rewritten in terms of Ruelle spectral functions, whose spectrum is encoded in the Patterson-Selberg function of three-dimensional hyperbolic geometry.
On -Functions for Laguerre Function Expansions of Hermite Type
Indian Academy of Sciences (India)
Błażej Jan Wróbel
2011-02-01
We examine weighted $L^p$ boundedness of -functions based on semi-groups related to multi-dimensional Laguerre function expansions of Hermite type. A technique of vector-valued Calderón–Zygmund operators is used.
Normality of Composite Analytic Functions and Sharing an Analytic Function
Xiao Bing; Yuan Wenjun; Wu Qifeng
2010-01-01
A result of Hinchliffe (2003) is extended to transcendental entire function, and an alternative proof is given in this paper. Our main result is as follows: let be an analytic function, a family of analytic functions in a domain , and a transcendental entire function. If and share IM for each pair , and one of the following conditions holds: (1) has at least two distinct zeros for any ; (2) is nonconstant, and there exists such that has only one distinct zero , and su...
Van der Waals density functional: an appropriate exchange functional
Cooper, Valentino R.
2009-01-01
In this paper, an exchange functional which is compatible with the non-local Rutgers-Chalmers correlation functional (vdW-DF) is presented. This functional, when employed with vdW-DF, demonstrates remarkable improvements on intermolecular separation distances while further improving the accuracy of vdW-DF interaction energies. The key to the success of this three parameter functional is its reduction of short range exchange repulsion through matching to the gradient exchange approximation in ...
International Nuclear Information System (INIS)
We have written a library of function classes in C++, which is distributed as part of the CLHEP foundation class libraries for High Energy Physics. The main goals of the library are to provide objects having all the mathematical behavior of functions, and to provide a mechanism for parameterizing these functions. Our functions support all the normal function operations such as addition, subtraction, multiplication, division, composition, et. cetera. The library allows programmers to compose complicated one-or multi-dimensional functions with great economy and natural semantics
Directory of Open Access Journals (Sweden)
Giuseppe Dattoli
1996-05-01
Full Text Available q analog of bessel functions, symmetric under the interchange of q and q^ −1 are introduced. The definition is based on the generating function realized as product of symmetric q-exponential functions with appropriate arguments. Symmetric q-Bessel function are shown to satisfy various identities as well as second-order q-differential equations, which in the limit q → 1 reproduce those obeyed by the usual cylindrical Bessel functions. A brief discussion on the possible algebraic setting for symmetric q-Bessel functions is also provided.
Reflection algebra and functional equations
Energy Technology Data Exchange (ETDEWEB)
Galleas, W., E-mail: w.galleas@uu.nl; Lamers, J., E-mail: j.lamers@uu.nl
2014-09-15
In this work we investigate the possibility of using the reflection algebra as a source of functional equations. More precisely, we obtain functional relations determining the partition function of the six-vertex model with domain-wall boundary conditions and one reflecting end. The model's partition function is expressed as a multiple-contour integral that allows the homogeneous limit to be obtained straightforwardly. Our functional equations are also shown to give rise to a consistent set of partial differential equations satisfied by the partition function.
Generalization of Hopf Functional Equation
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
This paper generalizes the Hopf functional equation in order to apply it to a wider class of not necessarily incompressible fluid flows. We start by defining characteristic functionals of the velocity field, the density field and the temperature field of a compressible field. Using the continuity equation, the Navier-Stokes equations and the equation of energy we derive a functional equation governing the motion of an ideal gas flow and a van der Waals gas flow, and then give some general methods of deriving a functional equation governing the motion of any compressible fluid flow. These functional equations can be considered as the generalization of the Hopf functional equation.
Completely monotonic functions related to logarithmic derivatives of entire functions
DEFF Research Database (Denmark)
Pedersen, Henrik Laurberg
2011-01-01
The logarithmic derivative l(x) of an entire function of genus p and having only non-positive zeros is represented in terms of a Stieltjes function. As a consequence, (-1)p(xml(x))(m+p) is a completely monotonic function for all m ≥ 0. This generalizes earlier results on complete monotonicity...
THE BOREL DIRECTIONS OF ALGEBROIDAL FUNCTION AND ITS COEFFICIENT FUNCTIONS
Institute of Scientific and Technical Information of China (English)
张少华; 张晓梅; 孙道椿
2014-01-01
In this article, the relationship between the Borel direction of algebroidal function and its coefficient functions is studied for the first time. To begin with, several theorems of algebroidal functions in unit disk are proved. By these theorems, some interesting conclusions are obtained.
RELAXATION OF FUNCTIONALS INVOLVING HOMOGENEOUS FUNCTIONS AND INVARIANCE OF ENVELOPES
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
The authors compute the quasiconvex envelope of certain functions defined on the space Mmn of real m× n matrices via a homogeneous function on Mmn. They also deduce invariance properties for various convex envelopes from corresponding invariance properties satisfied by a function. Some applications related in particular to nonlinear elasticity are given.
Energy Technology Data Exchange (ETDEWEB)
Sorichter, S. [Universitaetsklinikum Freiburg, Abteilung Pneumologie, Freiburg (Germany)
2009-08-15
The term lung function is often restricted to the assessment of volume time curves measured at the mouth. Spirometry includes the assessment of lung volumes which can be mobilised with the corresponding flow-volume curves. In addition, lung volumes that can not be mobilised, such as the residual volume, or only partially as FRC and TLC can be measured by body plethysmography combined with the determination of the airway resistance. Body plethysmography allows the correct positioning of forced breathing manoeuvres on the volume-axis, e.g. before and after pharmacotherapy. Adding the CO single breath transfer factor (T{sub LCO}), which includes the measurement of the ventilated lung volume using He, enables a clear diagnosis of different obstructive, restrictive or mixed ventilatory defects with and without trapped air. Tests of reversibility and provocation, as well as the assessment of inspiratory mouth pressures (PI{sub max}, P{sub 0.1}) help to classify the underlying disorder and to clarify treatment strategies. For further information and to complete the diagnostic of disturbances of the ventilation, diffusion and/or perfusion (capillar-)arterial bloodgases at rest and under physical strain sometimes amended by ergospirometry are recommended. Ideally, lung function measurements are amended by radiological and nuclear medicine techniques. (orig.) [German] Unter dem Begriff Lungenfunktion wird die Bestimmung der Lungenvolumina am Mund verstanden. Dabei werden die mobilisierbaren Lungenvolumina mit den zugehoerigen Fluss-Volumen-Kurven mittels Spirometrie und Ganzkoerperplethysmographie (GKP) und die nicht (RV) und teilweise mobilisierbaren Lungenvolumina (FRC, TLC) einschliesslich der Atemwegswiderstaende bestimmt. Die GKP ermoeglicht zusaetzlich die korrekte (Volumenachsen-)Positionierung der forcierten Atemmanoever. Dieses erlaubt eine uebersichtlichere graphische Darstellung z. B. vor und nach der Applikation pharmakologisch wirksamer Substanzen. Wird die GKP
Functional organic nanomaterials
Kohlmeyer, Ryan R.
focused on passive material properties such as mechanical, electrical, and thermal, there is growing interest in harnessing active material functions such as actuation, sensing, and power generation in designed CNT-polymer materials. The synergy between CNTs and the polymer matrix has been judiciously exploited to create highly desirable active material functions in smart material systems. By incorporating CNTs in a Nafion matrix, multi-shape memory healable composites capable of reversible remote, local, and chemical programming have been developed.
Cognition and brain functional aging
Directory of Open Access Journals (Sweden)
Hui-jie LI
2014-03-01
Full Text Available China has the largest population of elderly adults. Meanwhile, it is one of the countries showing fastest aging speed in the world. Aging processing is always companied with a series of brain structural and functional changes, which result in the decline of processing speed, working memory, long-term memory and executive function, etc. The studies based on functional magnetic resonance imaging (fMRI found certain aging effects on brain function activation, spontaneous activity and functional connectivity in old people. However, few studies have explored the brain functional curve during the aging process while most previous studies explored the differences in the brain function between young people and old people. Delineation of the human brain functional aging curve will promote the understanding of brain aging mechanisms and support the normal aging monitoring and early detection of abnormal aging changes. doi: 10.3969/j.issn.1672-6731.2014.03.005
Weakly $omega$-continuos functions
Directory of Open Access Journals (Sweden)
H. Al-Jarah
2010-07-01
Full Text Available The purpose of this paper is to introduce a new class of functions called weakly w-continous which contains the class of w-continuous functions and investigate their basic properties.
Vairo Antonio
2014-01-01
We discuss divergences of loop functions in thermal QCD and compute perturbatively the Polyakov loop, the Polyakov loop correlator and the cyclic Wilson loop. We show how these functions get mixed under renormalization.
Directory of Open Access Journals (Sweden)
Vairo Antonio
2014-01-01
Full Text Available We discuss divergences of loop functions in thermal QCD and compute perturbatively the Polyakov loop, the Polyakov loop correlator and the cyclic Wilson loop. We show how these functions get mixed under renormalization.
Cranial functional (psychogenic) movement disorders.
Kaski, Diego; Bronstein, Adolfo M; Edwards, Mark J; Stone, Jon
2015-12-01
Functional (psychogenic) neurological symptoms are frequently encountered in neurological practice. Cranial movement disorders--affecting the eyes, face, jaw, tongue, or palate--are an under-recognised feature of patients with functional symptoms. They can present in isolation or in the context of other functional symptoms; in particular, for functional eye movements, positive clinical signs such as convergence spasms can be triggered by the clinical examination. Although the specialty of functional neurological disorders has expanded, appreciation of cranial functional movement disorders is still insufficient. Identification of the positive features of cranial functional movement disorders such as convergence and unilateral platysmal spasm might lend diagnostic weight to a suspected functional neurological disorder. Understanding of the differential diagnosis, which is broad and includes many organic causes (eg, stroke), is essential to make an early and accurate diagnosis to prevent complications and initiate appropriate management. Increased understanding of these disorders is also crucial to drive clinical trials and studies of individually tailored therapies. PMID:26581970
More About Donsker's Delta Function
Lascheck, Angelika; Leukert, Peter; Streit, Ludwig; Westerkamp, Werner
2003-01-01
We discuss Donsker's delta function within the framework of White Noise Analysis, in particular its extension to complex arguments. With a view towards applications to quantum physics we also study sums and products of Donsker's delta functions.
Cryptographic Hash functions - a review
Directory of Open Access Journals (Sweden)
Rajeev Sobti
2012-03-01
Full Text Available Cryptographic Hash functions are used to achieve a number of security objectives. In this paper, we bring out the importance of hash functions, its various structures, design techniques, attacks and the progressive recent development in this field.
Exponential generating functions for the associated Bessel functions
International Nuclear Information System (INIS)
Similar to the associated Legendre functions, the differential equation for the associated Bessel functions Bl,m(x) is introduced so that its form remains invariant under the transformation l → -l - 1. A Rodrigues formula for the associated Bessel functions as squared integrable solutions in both regions l l,m(x) may be taken into account as the union of the increasing (decreasing) infinite sequences with respect to l. It is shown that two new different types of exponential generating functions are attributed to the associated Bessel functions corresponding to these rearranged sequences
Changes in gastrointestinal tract function and structure in functional dyspepsia.
Vanheel, Hanne; Farré, Ricard
2013-03-01
Functional dyspepsia is an extremely common disorder of gastrointestinal function. The disorder is thought to be heterogeneous, with different pathophysiological mechanisms underlying varied symptom patterns. A diversity of changes in gastrointestinal tract function and structure has been described in functional dyspepsia. These involve alterations in the stomach, such as impaired accommodation, delayed gastric emptying and hypersensitivity, and alterations in the duodenum, such as increased sensitivity to duodenal acid and/or lipids and low-grade inflammation. In this Review, we summarize all these abnormalities in an attempt to provide an integrated overview of the pathophysiological mechanisms in functional dyspepsia. PMID:23318268
International Nuclear Information System (INIS)
Despite the differences, traditionally domestic safeguards approaches have often been used for international safeguards, sometimes with a few modest changes. Given the extreme discrepancies between the goals, operational context and potential adversaries of the two, such easy solutions may be detrimental to long-term nuclear security. Domestic MPC and A personnel and hardware are not automatically appropriate for international treaty monitoring or for international auditing. International inspectors, such as used by the IAEA, need tools and training specific for their treaty monitoring mission, not just duplicated from (U.S.) domestic MPC and A approaches. Domestic 'cost-effective' solutions may turn out to be highly ineffective and thus expensive and detrimental to long-term nuclear security when applied in new contextual settings. Emphasis should be given to optimize approaches and hardware specifically designed for international safeguards and for future treaty monitoring (e.g. under a Fissile Material Cut-Off Treaty). To the extent international applications are to be borrowed from domestic approaches, much caution should be given to assess all aspects of the unique nuclear husbandry function in question (objective, obstacles to implementation, potential adversaries etc.), before any fielding of devices or systems
Weinstein, Steven
2016-01-01
Noise is widely understood to be something that interferes with a signal or process. Thus, it is generally thought to be destructive, obscuring signals and interfering with function. However, early in the 20th century, mechanical engineers found that mechanisms inducing additional vibration in mechanical systems could prevent sticking and hysteresis. This so-called "dither" noise was later introduced in an entirely different context at the advent of digital information transmission and recording in the early 1960s. Ironically, the addition of noise allows one to preserve information that would otherwise be lost when the signal or image is digitized. As we shall see, the benefits of added noise in these contexts are closely related to the phenomenon which has come to be known as stochastic resonance, the original version of which appealed to noise to explain how small periodic fluctuations in the eccentricity of the earth's orbit might be amplified in such a way as to bring about the observed periodic transiti...
DEFF Research Database (Denmark)
Andersen, C K; Andersen, K; Kragh-Sørensen, P
2000-01-01
a regression model based on the quality of its predictions. In exploring the econometric issues, the objective of this study was to estimate a cost function in order to estimate the annual health care cost of dementia. Using different models, health care costs were regressed on the degree of dementia, sex, age...... on these criteria, a two-part model was chosen. In this model, the probability of incurring any costs was estimated using a logistic regression, while the level of the costs was estimated in the second part of the model. The choice of model had a substantial impact on the predicted health care costs, e.......g. for a mildly demented patient, the estimated annual health care costs varied from DKK 71 273 to DKK 90 940 (US$ 1 = DKK 7) depending on which model was chosen. For the two-part model, the estimated health care costs ranged from DKK 44714, for a very mildly demented patient, to DKK 197 840, for a severely...
Holographic Three point Functions
DEFF Research Database (Denmark)
Martirosyan, Ara
. In the spirit of understanding this problem better, the thesis discusses the divergences appearing in the calculation of structure constants involving two giant and one point-like gravitons in the string theories on AdS_5 x S^5 and AdS_4 x S^7/Z_k backgrounds. Coherent state approach for the tree......The main subject of this thesis is the computation of structure constants appearing in the three-point functions for certain type of states/operators in the context of the AdS/CFT correspondence, which is one of the important parts of the dynamical problem in the dual theories of the correspondence......-level calculation of structure constants for heavy-heavy-light operators in the SU(2) x SU(2) sector of the ABJM theory is carried out both on weak and strong coupling sides of the theory. Another remarkable determinant-result is obtained in the same sector of ABJM theory using integrability techniques...
Bulte, Daniel
2016-01-01
Oxygen plays a fundamental role in functional magnetic resonance imaging (FMRI). Blood oxygenation level-dependent (BOLD) imaging is the foundation stone of all FMRI and is still the essential workhorse of the vast majority of FMRI procedures. Hemoglobin may provide the magnetic properties that allow the technique to work, but it is oxygen that allows the contrast to effectively be switched on or off, and it is oxygen that we are interested in tracking in order to observe the oxygen metabolism changes. In general the changes in venous oxygen saturation are observed in order to infer changes in the correlated mechanisms, which can include changes in cerebral blood flow, metabolism, and the fraction of inspired oxygen. By independently manipulating the fraction of inspired oxygen it is possible to alter the amount of dissolved oxygen in the plasma, the venous saturation, or even the blood flow. The effects that these changes have on the observed MRI signal can be either a help or a hindrance depending on how well the changes induced are understood. The administration of supplemental inspired oxygen is in a unique position to provide a flexible, noninvasive, inexpensive, patient-friendly addition to the MRI toolkit to enable investigations to look beyond statistics and regions of interest, and actually produce calibrated, targeted measurements of blood flow, metabolism or pathology. PMID:27343097
Functional modular contact lens
Shum, Angela J.; Cowan, Melissa; Lähdesmäki, Ilkka; Lingley, Andrew; Otis, Brian; Parviz, Babak A.
2009-08-01
Tear fluid offers a potential route for non-invasive sensing of physiological parameters. Utilization of this potential depends on the ability to manufacture sensors that can be placed on the surface of the eye. A contact lens makes a natural platform for such sensors, but contact lens polymers present a challenge for sensor fabrication. This paper describes a microfabrication process for constructing sensors that can be integrated into the structure of a functional contact lens in the future. To demonstrate the capabilities of the process, an amperometric glucose sensor was fabricated on a polymer substrate. The sensor consists of platinum working and counter electrodes, as well as a region of indium-tin oxide (ITO) for glucose oxidase immobilization. An external silver-silver chloride electrode was used as the reference electrode during the characterization experiments. Sensor operation was validated by hydrogen peroxide measurements in the 10- 20 μM range and glucose measurements in the 0.125-20 mM range.
Functional neuroanatomy of tics.
Neuner, Irene; Schneider, Frank; Shah, N Jon
2013-01-01
The therapeutic success of haloperidol in the treatment of Tourette syndrome (TS) put an end to the discussion about a "hysteric" or "neurotic" origin of TS. The cortico-striato-thalamo-cortical circuit has been identified as an underlying neurobiological correlate of TS. In this review we explore the main findings of structural alterations in TS including cortical areas, basal ganglia, hippocampus, amygdala, midbrain, and cerebellum. Based on the structural changes we examine the functional pattern described by the findings of fMRI and (15)O-PET/(18)FDG PET investigations. From the neuroimaging findings a cortical origin of the generation of tics is indicated. Future research on the neuronal footprint of TS should be directed towards addressing the question of which patterns of connectivity distinguish individuals in whom tics disappear during early adulthood from those in whom the tics persist. The understanding of this pathomechanism could provide a key on how to influence dysconnectivity in TS, for example, by more specific pharmaceutical intervention or by individually adopted EEG and/or fMRI neurofeedback.
Muniz, R.; Martinez, El; Szafran, J.; Dalton, A.
2011-01-01
The Function Point Analysis (FPA) Depot is a web application originally designed by one of the NE-C3 branch's engineers, Jamie Szafran, and created specifically for the Software Development team of the Launch Control Systems (LCS) project. The application consists of evaluating the work of each developer to be able to get a real estimate of the hours that is going to be assigned to a specific task of development. The Architect Team had made design change requests for the depot to change the schema of the application's information; that information, changed in the database, needed to be changed in the graphical user interface (GUI) (written in Ruby on Rails (RoR and the web service/server side in Java to match the database changes. These changes were made by two interns from NE-C, Ricardo Muniz from NE-C3, who made all the schema changes for the GUI in RoR and Edwin Martinez, from NE-C2, who made all the changes in the Java side.
Functional electrospun membranes
Ognibene, G.; Fragalà, M. E.; Cristaldi, D. A.; Blanco, I.; Cicala, G.
2016-05-01
In this study we combined electrospun PES nanofibers with ZnO nanostructures in order to obtain a hierarchical nanostructured hybrid material to be use for active water filtration membranes. It benefits of flexibility and high surface area of the polymeric nanofibers as well as of additional functionalities of ZnOnanostructures. First, randomly oriented nanofibers with diameters of 716nm ±365 nm were electrospun on a glass fibers substrate from a solution of PES and DMF-TOL(1:1). ZnO nanorods were grown onto the surface of electrospun PES fibers by a Chemical Bath Deposition (CBD) process. It was preceed by a seeding process necessary to form nucleation sites for the subsequent radially aligned growth of ZnO nanowires. The morfology of the fibers and the effect of the seeding time have been analysed by SEM. The amount of ZnO nanowires grown over electrospun nanofibers was determined as 45% by weight. The high purity and crystallinity of the asobtained products are confirmed by XRD since all reflection peaks can be indexed to hexagonal wurtzite ZnO.
Geometric Operators on Boolean Functions
Frisvad, Jeppe Revall; Falster, Peter
2007-01-01
In truth-functional propositional logic, any propositional formula represents a Boolean function (according to some valuation of the formula). We describe operators based on Decartes' concept of constructing coordinate systems, for translation of a propositional formula to the image of a Boolean function. With this image of a Boolean function corresponding to a propositional formula, we prove that the orthogonal projection operator leads to a theorem describing all rules of inference in propo...
Periodic functions with variable period
Pryjmak, M. V
2010-01-01
The examples of rhythmical signals with variable period are considered. The definition of periodic function with the variable period is given as a model of such signals. The examples of such functions are given and their variable periods are written in the explicit form. The system of trigonometric functions with the variable period is considered and its orthogonality is proved. The generalized system of trigonometric functions with the variable period is also suggested; some conditions of it...
Protein Functionality in Food Systems
Institute of Scientific and Technical Information of China (English)
WANG Panpan
2010-01-01
The structure,shape,color,smell and taste of food were decided by protein functionality.The utilization of protein will improve by changing the protein functionality.Protein functionality is also advantage to maintain and utilize the nutrition of food.This paper summarized the nature,classification,factors and prospect of protein functionality.It ccn provide a theoretical basis for application of protein in food industry.
Nonlinear potentials in function spaces
Rao, Murali; Vondraček, Zoran
2002-01-01
We introduce a framework for a nonlinear potential theory without a kernel on a reflexive, strictly convex and smooth Banach space of functions. Nonlinear potentials are defined as images of nonnegative continuous linear functionals on that space under the duality mapping. We study potentials and reduced functions by using a variant of the Gauss-Frostman quadratic functional. The framework allows a development of other main concepts of nonlinear potential theory such as capa...
INTEGRATIVE FASCIAL RELEASE & FUNCTIONAL TESTING
Hammer, Warren
2000-01-01
Soft tissue techniques, including Integrative Myofascial Release (IFR) can be more effective if the area of treatment can be determined by functional testing. The patient’s source of pain may not necessarily be located at the area of complaint and functional testing helps in pinpointing the source. Post-treatment functional testing will provide feedback to both the patient and the doctor as to whether the technique was effective. This paper will describe some typical functional tests and trea...
Van der Waals density functional: an appropriate exchange functional
Cooper, Valentino R
2009-01-01
In this paper, an exchange functional which is compatible with the non-local Rutgers-Chalmers correlation functional (vdW-DF) is presented. This functional, when employed with vdW-DF, demonstrates remarkable improvements on intermolecular separation distances while further improving the accuracy of vdW-DF interaction energies. The key to the success of this three parameter functional is its reduction of short range exchange repulsion through matching to the gradient exchange approximation in the slowly varying/high density limit while recovering the large reduced gradient, s, limit set in the revised PBE exchange functional. This augmented exchange functional could be a solution to long-standing issues of vdW-DF lending to further applicability of density functional theory to the study of relatively large, dispersion bound (van der Waals) complexes.
A functional RG equation for the c-function
DEFF Research Database (Denmark)
Codello, A.; D'Odorico, G.; Pagani, C.
2014-01-01
After showing how to prove the integrated c-theorem within the functional RG framework based on the effective average action, we derive an exact RG flow equation for Zamolodchikov's c-function in two dimensions by relating it to the flow of the effective average action. In order to obtain a non......-trivial flow for the c-function, we will need to understand the general form of the effective average action away from criticality, where nonlocal invariants, with beta functions as coefficients, must be included in the ansatz to be consistent. Then we apply our construction to several examples: exact results......, local potential approximation and loop expansion. In each case we construct the relative approximate c-function and find it to be consistent with Zamolodchikov's c-theorem. Finally, we present a relation between the c-function and the (matter induced) beta function of Newton's constant, allowing us...
Proposals for iterated hash functions
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Thomsen, Søren Steffen
2006-01-01
The past few years have seen an increase in the number of attacks on cryptographic hash functions. These include attacks directed at specific hash functions, and generic attacks on the typical method of constructing hash functions. In this paper we discuss possible methods for protecting against ...
Construction of optimized Boolean functions
Institute of Scientific and Technical Information of China (English)
CHEN Wei; YANG Yi-xian; NIU Xin-xin
2006-01-01
Considering connections of characteristics,this paper is aimed at the construction of optimized Boolean functions.A new method based on the Bent function,discrete Walsh spectrum and characteristics matrices are presented by concatenating,breaking,and revising output sequences conditionally.This new construction can be used to construct different kinds of functions satisfying different design criteria.
Cohomology and Bessel functions Theory
Mekhfi, Mustapha
2002-01-01
By studying cohomological quantum mechanics on the punctured plane,we were led to identify (reduced) Bessel functions with homotopic loops living on the plane.This identification led us to correspondence rules between exponentials and Bessel functions.The use of these rules makes us retrieve known but also new formulas in Bessel functions theory.
Rogov, V. -B. K.
2000-01-01
The modified q-Bessel functions and the q-Bessel-Macdonald functions of the first and second kind are introduced. Their definition is based on representations as power series. Recurrence relations, the q-Wronskians, asymptotic decompositions and q-integral representations are received. In addition, the q-Bessel-Macdonald function of kind 3 is determined by its q-integral representation.
[Diagnosis of functional bowel diseases].
Kruis, W
2007-02-28
Functional bowel disorders cause frequent doctor visits. The term comprises various disease entities. Most frequent are the irritable bowel syndrome, functional constipation and functional diarrhea. An exact history plays an outstanding role for the diagnosis of all these entities. History either confirms a positive diagnosis or initiates some complementary investigations. Redundant and dangerous technical procedures should be avoided in the diagnostic work up.
Simulation Methods for Functional Materials
Institute of Scientific and Technical Information of China (English)
Youqi Yang
2004-01-01
@@ Functional materials embrace a broad area, ranging from functional information materials to special polymers, from special chemicals for printing to materials used in making paints. Inasmuch as most functional materials are particulate, the present contribution is considered pertinent to the present FORUM.
Differentiability of functions of matrices
Grabovsky, Yury; Hijab, Omar; Rivin, Igor
2003-01-01
Given a function on diagonal matrices, there is a unique way to extend this to an invariant (by conjugation) function on symmetric matrices. We show that the extension preserves regularity -- that is, if the original function is k times differentiable so is the extension (likewise for analyticity and the class k+alpha).
Bernstein functions theory and applications
Schilling, René L; Vondracek, Zoran
2010-01-01
This text is a self-contained and unified approach to Bernstein functions and their subclasses, bringing together old and establishing new connections. Applications of Bernstein functions in different fields of mathematics are given, with special attention to interpretations in probability theory. An extensive list of complete Bernstein functions with their representations is provided.
Functional Similarity and Interpersonal Attraction.
Neimeyer, Greg J.; Neimeyer, Robert A.
1981-01-01
Students participated in dyadic disclosure exercises over a five-week period. Results indicated members of high functional similarity dyads evidenced greater attraction to one another than did members of low functional similarity dyads. "Friendship" pairs of male undergraduates displayed greater functional similarity than did "nominal" pairs from…
DEFF Research Database (Denmark)
Madsen, Per Printz
1999-01-01
The purpose of this paper is to describe a neural network (SNN), that is based on Shannons ideas of reconstruction of a real continuous function from its samples. The basic function, used in this network, is the Sinc-function. Two learning algorithms are described. A simple one called IM...
Applications of functionalized ionic liquids
Institute of Scientific and Technical Information of China (English)
LI Xuehui; ZHAO Dongbin; FEI Zhaofu; WANG Lefu
2006-01-01
Recent developments of the synthesis and applications of functionalized ionic liquids(including dual-functionalized ionic liquids) have been highlighted in this review. Ionic liquids are attracting attention as alternative solvents in green chemistry, but as more functionalized ILs are prepared, a greater number of applications in increasingly diverse fields are found.
Proposals for Iterated Hash Functions
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Thomsen, Søren Steffen
2008-01-01
The past few years have seen an increase in the number of attacks on cryptographic hash functions. These include attacks directed at specific hash functions, and generic attacks on the typical method of constructing hash functions. In this paper we discuss possible methods for protecting against ...
A lung function information system
A.F.M. Verbraak (Anton); E.J. Hoorn (Ewout); J. de Vries (Julius); J.M. Bogaard (Jan); A. Versprille (Adrian)
1991-01-01
markdownabstractAbstract A lung function information system (LFIS) was developed for the data analysis of pulmonary function tests at different locations. This system was connected to the hospital information system (HIS) for the retrieval of patient data and the storage of the lung function varia
Staircase and Fractional Part Functions
Amram, Meirav; Dagan, Miriam; Ioshpe, Michael; Satianov, Pavel
2016-01-01
The staircase and fractional part functions are basic examples of real functions. They can be applied in several parts of mathematics, such as analysis, number theory, formulas for primes, and so on; in computer programming, the floor and ceiling functions are provided by a significant number of programming languages--they have some basic uses in…
DEFF Research Database (Denmark)
Henglein, Fritz
2009-01-01
What is a sorting function—not a sorting function for a given ordering relation, but a sorting function with nothing given? Formulating four basic properties of sorting algorithms as defining requirements, we arrive at intrinsic notions of sorting and stable sorting: A function is a sorting funct...
DEFF Research Database (Denmark)
Madsen, Per Printz
1998-01-01
The purpose of this paper is to describe a neural network (SNN), that is based on Shannons ideas of reconstruction of a real continuous function from its samples. The basic function, used in this network, is the Sinc-function. Two learning algorithms are described. A simple one called IM...
Evolutionary Design of Boolean Functions
Institute of Scientific and Technical Information of China (English)
WANG Zhang-yi; ZHANG Huan-guo; QIN Zhong-ping; MENG Qing-shu
2005-01-01
We use evolutionary computing to synthesize Boolean functions randomly. By using specific crossover and mutation operator in evolving process and modifying search space and fitness function, we get some high non-linearity functions which have other good cryptography characteristics such as autocorrelation etc. Comparing to other heuristic search techniques, evolutionary computing approach is more effective because of global search strategy and implicit parallelism.
Banach spaces of analytic functions
Hoffman, Kenneth
2007-01-01
A classic of pure mathematics, this advanced graduate-level text explores the intersection of functional analysis and analytic function theory. Close in spirit to abstract harmonic analysis, it is confined to Banach spaces of analytic functions in the unit disc.The author devotes the first four chapters to proofs of classical theorems on boundary values and boundary integral representations of analytic functions in the unit disc, including generalizations to Dirichlet algebras. The fifth chapter contains the factorization theory of Hp functions, a discussion of some partial extensions of the f
Methylmercury toxicity and functional programming
DEFF Research Database (Denmark)
Grandjean, Philippe
2007-01-01
PURPOSE: Adverse health effects of developmental toxicants may induce abnormal functional programming that leads to lasting functional deficits. This notion is considered from epidemiological evidence using developmental methylmercury neurotoxicity as an example. MOST IMPORTANT FINDINGS: Accumula......PURPOSE: Adverse health effects of developmental toxicants may induce abnormal functional programming that leads to lasting functional deficits. This notion is considered from epidemiological evidence using developmental methylmercury neurotoxicity as an example. MOST IMPORTANT FINDINGS...... by neurodevelopmental methylmercury toxicity fit into the pattern of functional programming, with effects opposite to those linked to beneficial stimuli....
Nongenetic functions of the genome.
Bustin, Michael; Misteli, Tom
2016-05-01
The primary function of the genome is to store, propagate, and express the genetic information that gives rise to a cell's architectural and functional machinery. However, the genome is also a major structural component of the cell. Besides its genetic roles, the genome affects cellular functions by nongenetic means through its physical and structural properties, particularly by exerting mechanical forces and by serving as a scaffold for binding of cellular components. Major cellular processes affected by nongenetic functions of the genome include establishment of nuclear structure, signal transduction, mechanoresponses, cell migration, and vision in nocturnal animals. We discuss the concept, mechanisms, and implications of nongenetic functions of the genome.
Density Functional Approach Based on Numerically Obtained Bridge Functional
Institute of Scientific and Technical Information of China (English)
ZHOUShi－Qi
2002-01-01
The ornstein-zenike equation is solved with the Rogers-Young approximation for bulk hard sphere fluid and Lennard-Jones fluid for several state points.Then the resulted bulk fluid radial distribution function combined with the test particle method is employed to determine numerically the function relationship of bridge functional as a function of indirect correlation function.It is found that all of the calculated points from different phase space state points for a same type of fluid collapse onto a same smooth curve.Then the numerically obtained curve is used to substitute the analytic expression of the bridge functional as a function of indirect correlation function required in the methodology [J.Chem.Phys,112(2000)8079] to determine the density distribution of non-uniform hard sphere fluid and Lennard-Jones fluid.The good agreement of theoretical predictions with the computer simulation data is obtained.The present numerical procedure incroporates the knowledge of bulk fluid radial distribution function into the constructing of the density functional approximation and makes the original methodology more accurate and more filexible for various interaction potential fluid.
Functional Programming in Computer Science
Energy Technology Data Exchange (ETDEWEB)
Anderson, Loren James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Davis, Marion Kei [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2016-01-19
We explore functional programming through a 16-week internship at Los Alamos National Laboratory. Functional programming is a branch of computer science that has exploded in popularity over the past decade due to its high-level syntax, ease of parallelization, and abundant applications. First, we summarize functional programming by listing the advantages of functional programming languages over the usual imperative languages, and we introduce the concept of parsing. Second, we discuss the importance of lambda calculus in the theory of functional programming. Lambda calculus was invented by Alonzo Church in the 1930s to formalize the concept of effective computability, and every functional language is essentially some implementation of lambda calculus. Finally, we display the lasting products of the internship: additions to a compiler and runtime system for the pure functional language STG, including both a set of tests that indicate the validity of updates to the compiler and a compiler pass that checks for illegal instances of duplicate names.
Radial basis function networks and complexity regularization in function learning.
Krzyzak, A; Linder, T
1998-01-01
In this paper we apply the method of complexity regularization to derive estimation bounds for nonlinear function estimation using a single hidden layer radial basis function network. Our approach differs from previous complexity regularization neural-network function learning schemes in that we operate with random covering numbers and l(1) metric entropy, making it possible to consider much broader families of activation functions, namely functions of bounded variation. Some constraints previously imposed on the network parameters are also eliminated this way. The network is trained by means of complexity regularization involving empirical risk minimization. Bounds on the expected risk in terms of the sample size are obtained for a large class of loss functions. Rates of convergence to the optimal loss are also derived.
Prediction Error During Functional and Non-Functional Action Sequences
DEFF Research Database (Denmark)
Nielbo, Kristoffer Laigaard; Sørensen, Jesper
2013-01-01
recurrent networks were made and the results are presented in this article. The simulations show that non-functional action sequences do indeed increase prediction error, but that context representations, such as abstract goal information, can modulate the error signal considerably. It is also shown......By means of the computational approach the present study investigates the difference between observation of functional behavior (i.e. actions involving necessary integration of subparts) and non-functional behavior (i.e. actions lacking necessary integration of subparts) in terms of prediction...... behavioral study has shown that human subjects segment non-functional behavior in a more fine-grained way than functional behavior. This increase in segmentation rate implies that non-functionality elicits a stronger error signal. To further explore the implications, two computer simulations using simple...
Functional principal components analysis of workload capacity functions
Burns, Devin M.; Houpt, Joseph W.; Townsend, James T.; Endres, Michael J.
2013-01-01
Workload capacity, an important concept in many areas of psychology, describes processing efficiency across changes in workload. The capacity coefficient is a function across time that provides a useful measure of this construct. Until now, most analyses of the capacity coefficient have focused on the magnitude of this function, and often only in terms of a qualitative comparison (greater than or less than one). This work explains how a functional extension of principal components analysis ca...
CHARACTERISTIC OF COMPOSITION MEROMORPHIC FUNCTIONS WITH DEFICIENT FUNCTIONS
Institute of Scientific and Technical Information of China (English)
SUN Jian-wu
2004-01-01
In this paper, we obtain the following result: Let f(z) be a meromorphic function of order ρ and lower order λ , let ai (z) ( I = 1,2,… n, n ≤ ∞ ) be entire function, which satisying T( r, ai (z) = o ( T( r ,f) ) with ∑ni=1δ(ai(z),f) = 1 andδ(ai(z),f) ＞ 0 (ai(z) (≠)∞).If lim T r→∞( r,f(z + 1))/ T(r,f(z)) = ∞.Then ρ=λ= ∞.We solved problem due to C. C. Yang concerning the characteristic functions of the composite functions.
Free Functional Muscle Transfers to Restore Upper Extremity Function.
Krauss, Emily M; Tung, Thomas H; Moore, Amy M
2016-05-01
Free functional muscle transfer provides an option for functional restoration when nerve reconstruction and tendon transfers are not feasible. To ensure a successful outcome, many factors need to be optimized, including proper patient selection, timing of intervention, donor muscle and motor nerve selection, optimal microneurovascular technique and tension setting, proper postoperative management, and appropriate rehabilitation. Functional outcomes of various applications to the upper extremity and the authors' algorithm for the use of free functional muscle transfer are also included in this article. PMID:27094895
Density Functional Approach Based on Numerically Obtained Bridge Functional
Institute of Scientific and Technical Information of China (English)
ZHOU Shi-Qi
2002-01-01
The Ornstein Zernike equation is solved with the Rogers Young approximation for bulk hard sphere fluidand Lennard-Jones fluid for several state points. Then the resulted bulk fluid radial distribution function combinedwith the test particle method is employed to determine numerically the function relationship of bridge functional as afunction of indirect correlation function. It is found that all of the calculated points from different phase space statepoints for a same type of fluid collapse onto a same smooth curve. Then the numerically obtained curve is used tosubstitute the analytic expression of the bridge functional as a function of indirect correlation function required in themethodology [J. Chem. Phys. 112 (2000) 8079] to deterrnine the density distribution of non-uniform hard spherefluid and Lennard Jones fluid. The good agreement of theoretical predictions with the computer simulation data isobtained. The present numerical procedure incorporates the knowledge of bulk fluid radial distribution function intothe constructing of the density functional approximation and makes the original methodology more accurate and moreflexible for various interaction potential fluid.
Staircase and fractional part functions
Amram, Meirav; Dagan, Miriam; Ioshpe, Michael; Satianov, Pavel
2016-10-01
The staircase and fractional part functions are basic examples of real functions. They can be applied in several parts of mathematics, such as analysis, number theory, formulas for primes, and so on; in computer programming, the floor and ceiling functions are provided by a significant number of programming languages - they have some basic uses in various programming tasks. In this paper, we view the staircase and fractional part functions as a classical example of non-continuous real functions. We introduce some of their basic properties, present some interesting constructions concerning them, and explore some intriguing interpretations of such functions. Throughout the paper, we use these functions in order to explain basic concepts in a first calculus course, such as domain of definition, discontinuity, and oddness of functions. We also explain in detail how, after researching the properties of such functions, one can draw their graph; this is a crucial part in the process of understanding their nature. In the paper, we present some subjects that the first-year student in the exact sciences may not encounter. We try to clarify those subjects and show that such ideas are important in the understanding of non-continuous functions, as a part of studying analysis in general.
Probabilistic aspects of Wigner function
Usenko, C V
2004-01-01
The Wigner function of quantum systems is an effective instrument to construct the approximate classical description of the systems for which the classical approximation is possible. During the last time, the Wigner function formalism is applied as well to seek indications of specific quantum properties of quantum systems leading to impossibility of the classical approximation construction. Most of all, as such an indication the existence of negative values in Wigner function for specific states of the quantum system being studied is used. The existence of such values itself prejudices the probabilistic interpretation of the Wigner function, though for an arbitrary observable depending jointly on the coordinate and the momentum of the quantum system just the Wigner function gives an effective instrument to calculate the average value and the other statistical characteristics. In this paper probabilistic interpretation of the Wigner function based on coordination of theoretical-probabilistic definition of the ...
Geometric Operators on Boolean Functions
DEFF Research Database (Denmark)
Frisvad, Jeppe Revall; Falster, Peter
In truth-functional propositional logic, any propositional formula represents a Boolean function (according to some valuation of the formula). We describe operators based on Decartes' concept of constructing coordinate systems, for translation of a propositional formula to the image of a Boolean...... function. With this image of a Boolean function corresponding to a propositional formula, we prove that the orthogonal projection operator leads to a theorem describing all rules of inference in propositional reasoning. In other words, we can capture all kinds of inference in propositional logic by means...... of a few geometric operators working on the images of Boolean functions. The operators we describe, arise from the niche area of array-based logic and have previously been tightly bound to an array-based representation of Boolean functions. We redefine the operators in an abstract form to make them...
Mechanics of advanced functional materials
Wang, Biao
2013-01-01
Mechanics of Advanced Functional Materials emphasizes the coupling effect between the electric and mechanical field in the piezoelectric, ferroelectric and other functional materials. It also discusses the size effect on the ferroelectric domain instability and phase transition behaviors using the continuum micro-structural evolution models. Functional materials usually have a very wide application in engineering due to their unique thermal, electric, magnetic, optoelectronic, etc., functions. Almost all the applications demand that the material should have reasonable stiffness, strength, fracture toughness and the other mechanical properties. Furthermore, usually the stress and strain fields on the functional materials and devices have some important coupling effect on the functionality of the materials. Much progress has been made concerning the coupling electric and mechanical behaviors such as the coupled electric and stress field distribution in piezoelectric solids, ferroelectric domain patterns in ferr...
The relativity of biological function.
Laubichler, Manfred D; Stadler, Peter F; Prohaska, Sonja J; Nowick, Katja
2015-12-01
Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics. Conflicting conceptions of function continue to be used in the scientific literature to support certain claims, for instance about the fraction of "functional DNA" in the human genome. Here we argue that all biologically meaningful interpretations of function are necessarily context dependent. This implies that they derive their meaning as well as their range of applicability only within a specific theoretical and measurement context. We use this framework to shed light on the current debate about functional DNA and argue that without considering explicitly the theoretical and measurement contexts all attempts to integrate biological theories are prone to fail. PMID:26449352
Markers of renal function tests
Directory of Open Access Journals (Sweden)
Shivaraj Gowda
2010-04-01
Full Text Available Background: The markers of renal function test assess the normal functioning of kidneys. These markers may be radioactive and non radioactive. They indicate the glomerular filtration rate, concentrating and diluting capacity of kidneys (tubular function. If there is an increase or decrease in the valves of these markers it indicates dysfunction of kidney. Aim: The aim of this review is to compare and analyze the present and newer markers of renal function tests which help in diagnosis of clinical disorders. Material & Methods: An extensive literature survey was done aiming to compare and compile renal function tests makers required in diagnosis of diseases. Results: Creatinine, urea, uric acid and electrolytes are makers for routine analysis whereas several studies have confirmed and consolidated the usefulness of markers such as cystatin C and β-Trace Protein. Conclusion: We conclude that further investigation is necessary to define these biomarkers in terms of usefulness in assessing renal function.
The relativity of biological function.
Laubichler, Manfred D; Stadler, Peter F; Prohaska, Sonja J; Nowick, Katja
2015-12-01
Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics. Conflicting conceptions of function continue to be used in the scientific literature to support certain claims, for instance about the fraction of "functional DNA" in the human genome. Here we argue that all biologically meaningful interpretations of function are necessarily context dependent. This implies that they derive their meaning as well as their range of applicability only within a specific theoretical and measurement context. We use this framework to shed light on the current debate about functional DNA and argue that without considering explicitly the theoretical and measurement contexts all attempts to integrate biological theories are prone to fail.
Clinical needs in functional imaging
Energy Technology Data Exchange (ETDEWEB)
Atkins, H.L.; Fairchild, R.G.; Richards, P.; Pate, H.
1979-01-01
Emission tomography, with positron or single photon emitting radionuclides, offers the possibility of quantitation, a necessary ingredient for functional studies. A figure of merit has been devised as an aid in selecting radionuclides that offer the greatest photon yield for the lowest radiation dose because emission tomography requires a greater information density than conventional imaging. Alterations in function generally precede anatomical alterations and functional imaging may therefore be a more sensitive method of investigating disease processes.
Dansk skepsis mod "functional foods"
DEFF Research Database (Denmark)
Bech-Larsen, Tino
2000-01-01
MAPP Centret har undersøgt danske, finske og amerikanske forbrugeres holdninger til functional foods og til genmodificerede fødevarer. Undersøgelsen er baseret på personlige interviews med 1500 danske, finske og nordamerikanske forbrugere. På trods af den store udbredelse af functional foods i USA......, viste undersøgelsen, at finnerne faktisk var mere positive over for functional foods end amerikanerne. De danske forbrugere var klart de mest skeptiske....
Gaussian Processes for Functional Autoregression
Kowal, Daniel R.; David S. Matteson; Ruppert, David
2016-01-01
We develop a hierarchical Gaussian process model for forecasting and inference of functional time series data. Unlike existing methods, our approach is especially suited for sparsely or irregularly sampled curves and for curves sampled with non-negligible measurement error. The latent process is dynamically modeled as a functional autoregression (FAR) with Gaussian process innovations. We propose a fully nonparametric dynamic functional factor model for the dynamic innovation process, with br...
Pulmonary Function Tests in Hypertension
Dr Swati Shah; Dr Mohiuddin Shaikh; Dr Yogesh Gupta; Dr Pradeep Nahar; Dr Urjita Zingade; Dr Arun Kowale
2014-01-01
Background: Many studies have shown that Hypertension is a chronic disease affecting many organs in the body. However, very few studies have been done to analyze the association between lung function and hypertension. It must be considered that antihypertensive treatment might have an effect on lung function, too. With this background the study was undertaken. Objectives: To assess and compare the pulmonary function tests (PFTs) in controlled hypertensive patients and; age and gender matched ...
Linear Processes for Functional Data
Mas, André; Pumo, Besnik
2009-01-01
International audience Linear processes on functional spaces were born about fifteen years ago. And this original topic went through the same fast development as the other areas of functional data modeling such as PCA or regression. They aim at generalizing to random curves the classical ARMA models widely known in time series analysis. They offer a wide spectrum of models suited to the statistical inference on continuous time stochastic processes within the paradigm of functional data. Es...
Functional polymer blends and nanocomposites
Weder, Christoph
2010-01-01
The broad class of (multi)functional polymers with unusual combinations of optical, electronic, mechanical and other properties is attracting significant interest, because it conceptually combines the advantages of polymers - low cost, ease of processing and a range of attractive mechanical characteristics - with the specific, tailorable properties of functional organic molecules. The caveat is that the synthesis of functional polymers is frequently complex and involves many steps, which make...
Erectile function after urethral reconstruction
Institute of Scientific and Technical Information of China (English)
Joshua Carlton; Maharshi Patel; Allen F. Morey
2008-01-01
Advances in urogenital plastic surgical tissue transfer techniques have enabled urethral reconstruction surgery to become the new gold-standard for treatment of refractory urethral stricture disease. Questions remain, however,regarding the long-term implications on sexual function after major genital reconstructive surgery. In this article, we review the pathologic features of urethral stricture disease and urologic trauma that may affect erectile function (EF) and assess the impact of various specific contemporary urethroplasty surgical techniques on male sexual function.
Functional foods in human nutrition
ZEVLOVÁ, Veronika
2013-01-01
Bachelor thesis deals with functional food and their role in human nutrition. The history of functional food, their characteristics, components, evaluation of individual species and the impact on the health of the consumer is described here. A lot of researches are focused on the topic of functional food, but no legally definition have been established yet. Even in the Czech Republic or the EU. Only the certain designations are used, which have a small deviations in different countries. Funct...
CAMAC modular programmable function generator
International Nuclear Information System (INIS)
A CAMAC modular programmable function generator has been developed. The device contains a 1024 word by 12-bit memory, a 12-bit digital-to-analog converter with a 600 ns settling time, an 18-bit programmable frequency register, and two programmable trigger output registers. The trigger registers can produce programmed output logic transitions at various (binary) points in the output function curve, and are used to synchronize various other data acquisition devices with the function curve
Executive functions in anorexia nervosa
Ignacio Jauregui-Lobera
2014-01-01
Introduction: The pathophysiologic mechanisms that account for the development and persistence of anorexia nervosa (AN) remain unclear. With respect to the neuropsychological functioning, the executive functions have been reported to be altered, especially cognitive flexibility and decision-making processes. Objectives: The aim of this study was to review the current state of the neuropsychological studies focused on anorexia nervosa, especially those highlighting the executive functions. Met...
Functionalizing Designer DNA Crystals
Chandrasekaran, Arun Richard
nucleotides is usually pH dependent (pH match the expected position of the TFO on the triangle motif. Since the additional density did not correspond to the entire binding region, 2Fo-Fc, 3Fo-2Fc and 4Fo-3Fc maps were done to check for missing pieces of the electron density. From the resulting 2Fo-Fc map, the asymmetric unit from the 3-turn triangle (31-bp duplex model based on previous structure 3UBI) was inserted into the density as a reference. However, the electron density corresponding to the TFO was still not continuous throughout the 13-nt triplex binding region and allowed only a partial fit of the TFO. The third nucleotide in positions 1, 3, 4, 6, 7 were fit into the density in the major groove of the underlying duplex with proper triplex configuration. The third chapter describes the triplex approach to position a functional group (the UV cross-linking agent psoralen) within a pre-formed DNA motif. Triplex formation and psoralen cross-linking of the motif were analyzed by native and denaturing gel electrophoresis respectively. Motifs containing the Psoralen-TFO were also successfully crystallized and the crosslinking shown by analyzing the denatured crystals on a gel. The end goal would be to form a crosslinked designed DNA crystal that can diffract to a higher resolution. The fourth chapter describes the use of serial femtosecond crystallography for structure determination of designed DNA lattices. X-ray diffraction data from self-assembled 3D DNA microcrystals were collected from a stream of crystals in solution. Serial femtosecond crystallography eliminates the need for large crystals and the need for freezing, thus overcoming any associated crystal defects and radiation damage. Self-assembled nano/microcrystals were successfully made and were diffracted at room temperature. The best diffraction was from the 1-nt SE motif to an extent of 3.5 A in resolution.
Functionalizing Designer DNA Crystals
Chandrasekaran, Arun Richard
nucleotides is usually pH dependent (pH < 6) four different TFOs were examined: TFO-1 was unmodified while TFOs 2-4 contained additional stabilizing analogues capable of extending triplex formation to pH 7. In addition, each of the TFOs contained a Cy5 dye at the 5'-end of the oligonucleotide to aid in characterization of TFO binding - crystals were obtained with all four variations of TFOs. Formation of DNA triplex in the motif was characterized by an electrophoretic mobility shift assay (EMSA), UV melting studies and FRET. Crystals containing TFO-1 (unmodified) and TFO-2 (with 2'-amino ethoxy modification) were isolated and flash-frozen in liquid nitrogen for X-ray data collection at beam line NSLS-X25. X-ray data was also collected for crystals of the 3-turn triangle without any TFO bound to it. Difference maps were done between the crystals with TFO against the one without to identify any additional electron density corresponding to the third strand in the triplex binding region. The data from the crystal containing TFO-2 was used to further analyze if the additional density can match the expected position of the TFO on the triangle motif. Since the additional density did not correspond to the entire binding region, 2Fo-Fc, 3Fo-2Fc and 4Fo-3Fc maps were done to check for missing pieces of the electron density. From the resulting 2Fo-Fc map, the asymmetric unit from the 3-turn triangle (31-bp duplex model based on previous structure 3UBI) was inserted into the density as a reference. However, the electron density corresponding to the TFO was still not continuous throughout the 13-nt triplex binding region and allowed only a partial fit of the TFO. The third nucleotide in positions 1, 3, 4, 6, 7 were fit into the density in the major groove of the underlying duplex with proper triplex configuration. The third chapter describes the triplex approach to position a functional group (the UV cross-linking agent psoralen) within a pre-formed DNA motif. Triplex formation and
Functional model realizations for Schur functions on C+
Kurula, Mikael; Ball, Joseph A.; Staffans, Olof J.; Zwart, Hans
2014-01-01
For an arbitrary given operator Schur function defined on the complex right-half plane, we give a controllable energy-preserving and an observable co-energy-preserving de Branges-Rovnyak functional model realization. Topics appearing only in the right-half-plane setting, such as the extrapolation sp
Approximation of Analytic Functions by Bessel's Functions of Fractional Order
Directory of Open Access Journals (Sweden)
Soon-Mo Jung
2011-01-01
Full Text Available We will solve the inhomogeneous Bessel's differential equation x2y″(x+xy′(x+(x2-ν2y(x=∑m=0∞amxm, where ν is a positive nonintegral number and apply this result for approximating analytic functions of a special type by the Bessel functions of fractional order.
Approximation of Analytic Functions by Bessel's Functions of Fractional Order
Soon-Mo Jung
2011-01-01
We will solve the inhomogeneous Bessel's differential equation x2y″(x)+xy′(x)+(x2-ν2)y(x)=∑m=0∞amxm, where ν is a positive nonintegral number and apply this result for approximating analytic functions of a special type by the Bessel functions of fractional order.
Speech and Language Functions that Require a Functioning Broca's Area
Davis, Cameron; Kleinman, Jonathan T.; Newhart, Melissa; Gingis, Leila; Pawlak, Mikolaj; Hillis, Argye E.
2008-01-01
A number of previous studies have indicated that Broca's area has an important role in understanding and producing syntactically complex sentences and other language functions. If Broca's area is critical for these functions, then either infarction of Broca's area or temporary hypoperfusion within this region should cause impairment of these…
Harmonic Morphisms Projecting Harmonic Functions to Harmonic Functions
Directory of Open Access Journals (Sweden)
M. T. Mustafa
2012-01-01
horizontal and vertical components. By comparing the Laplacians on M and N, we determine conditions under which a harmonic function on U=ϕ−1(V⊂M projects down, via its horizontal component, to a harmonic function on V⊂N.
Towards a comprehensive Functional Capacity Evaluation for hand function
Hollak, N; Soer, R; van der Woude, L H; Reneman, M F
2014-01-01
The aim of this study was to develop a more efficient (i.e. shortened) protocol for hand function capacity evaluation and to test the agreement of the protocol compared to the original protocol. 643 Healthy subjects performed tests for hand function. Agreement between two shortened protocols was com
Deriving bases for Abelian functions
England, Matthew
2011-01-01
We present a new method to explicitly define Abelian functions on algebraic curves, for the purpose of finding bases for the relevant vector spaces of such functions. We demonstrate the procedure with the functions associated to a trigonal curve of genus four. The main motivation for the construction of such bases is that it allows systematic methods for the derivation of the addition formulae and differential equations satis?ed by the functions. We present a new 3-term 2-variable addition formulae and a complete set of differential equations to generalise the classic Weierstrass identities for the case of the trigonal curve of genus four.
Molecular calculations with B functions
Steinborn, E O; Ema, I; López, R; Ramírez, G
1998-01-01
A program for molecular calculations with B functions is reported and its performance is analyzed. All the one- and two-center integrals, and the three-center nuclear attraction integrals are computed by direct procedures, using previously developed algorithms. The three- and four-center electron repulsion integrals are computed by means of Gaussian expansions of the B functions. A new procedure for obtaining these expansions is also reported. Some results on full molecular calculations are included to show the capabilities of the program and the quality of the B functions to represent the electronic functions in molecules.
Prestarlike functions with negative coefficients
Directory of Open Access Journals (Sweden)
H. Silverman
1979-01-01
Full Text Available The extreme points for prestarlike functions having negative coefficients are determined. Coefficient, distortion and radii of univalence, starlikeness, and convexity theorems are also obtained.
A deterministic width function model
Directory of Open Access Journals (Sweden)
C. E. Puente
2003-01-01
Full Text Available Use of a deterministic fractal-multifractal (FM geometric method to model width functions of natural river networks, as derived distributions of simple multifractal measures via fractal interpolating functions, is reported. It is first demonstrated that the FM procedure may be used to simulate natural width functions, preserving their most relevant features like their overall shape and texture and their observed power-law scaling on their power spectra. It is then shown, via two natural river networks (Racoon and Brushy creeks in the United States, that the FM approach may also be used to closely approximate existing width functions.
DEFF Research Database (Denmark)
Dahl, Jens Peder; Varro, S.; Wolf, A.;
2007-01-01
We derive explicit expressions for the Wigner function of wave functions in D dimensions which depend on the hyperradius-that is, of s waves. They are based either on the position or the momentum representation of the s wave. The corresponding Wigner function depends on three variables......: the absolute value of the D-dimensional position and momentum vectors and the angle between them. We illustrate these expressions by calculating and discussing the Wigner functions of an elementary s wave and the energy eigenfunction of a free particle....
Free Flap Functional Muscle Transfers.
Garcia, Ryan M; Ruch, David S
2016-08-01
Free functional muscle transfers remain a powerful reconstructive tool to restore upper extremity function when other options such as tendon or nerve transfers are not available. This reconstructive technique is commonly used for patients following trauma, ischemic contractures, and brachial plexopathies. Variable outcomes have been reported following free functional muscle transfers that are related to motor nerve availability and reinnervation. This article highlights considerations around donor motor nerve selection, dissection, and use of the gracilis muscle, and the surgical approach to performing a free functional muscle transfer to restore elbow flexion and/or digit flexion. PMID:27387083
Center for Functional Nanomaterials (CFN)
Federal Laboratory Consortium — The CFN at Brookhaven National Laboratory focuses on understanding the chemical and physical response of nanomaterials to make functional materials such as sensors,...
Pakeman, Robin J; Stockan, Jenni A
2014-05-01
Understanding how community assembly is controlled by the balance of abiotic drivers (environment or management) and biotic drivers (community composition of other groups) is important in predicting the response of ecosystems to environmental change. If there are strong links between plant assemblage structure and carabid beetle functional traits and functional diversity, then it is possible to predict the impact of environmental change propagating through different functional and trophic groups. Vegetation and pitfall trap beetle surveys were carried out across twenty four sites contrasting in land use, and hence productivity and disturbance regime. Plant functional traits were very successful at explaining the distribution of carabid functional traits across the habitats studied. Key carabid response traits appeared to be body length and wing type. Carabid functional richness was significantly smaller than expected, indicating strong environmental filtering, modulated by management, soil characteristics, and by plant response traits. Carabid functional divergence was negatively related to plant functional evenness, while carabid functional evenness was positively correlated to plant functional evenness and richness. The study shows that there are clear trait linkages between the plant and the carabid assemblage that act not only through the mean traits displayed, but also via their distribution in trait space; powerful evidence that both the mean and variance of traits in one trophic group structure the assemblage of another.
Technical Rebuilding of Movement Function Using Functional Electrical Stimulation
Gföhler, Margit
To rebuild lost movement functions, neuroprostheses based on functional electrical stimulation (FES) artificially activate skeletal muscles in corresponding sequences, using both residual body functions and artificial signals for control. Besides the functional gain, FES training also brings physiological and psychological benefits for spinal cord-injured subjects. In this chapter, current stimulation technology and the main components of FES-based neuroprostheses including enhanced control systems are presented. Technology and application of FES cycling and rowing, both approaches that enable spinal cord-injured subjects to participate in mainstream activities and improve their health and fitness by exercising like able-bodied subjects, are discussed in detail, and an overview of neuroprostheses that aim at restoring movement functions for daily life as walking or grasping is given.
Spontaneous processing of functional and non-functional action sequences
DEFF Research Database (Denmark)
Nielbo, Kristoffer Laigaard; Sørensen, Jesper
2011-01-01
have chosen to focus on the derivedness from instrumental behavior, intentional underspecification and goal-demotion. In contrast to instrumental or functional behavior (i.e., actions that cohere causally and have a necessary integration of subparts), we propose to view ritual and ritualized action...... as sub-categories of non-functional behavior (i.e., actions lacking causal coherence and a necessary integration between subparts). New insights in human action processing can help us explain how cognition might vary depending on the type of behavior processed. Using an event segmentation paradigm, we...... conducted two experiments eliciting differences in participants' response patterns to functional and non-functional actions. Participants consistently segmented non-functional action sequences into smaller units indicating either an attentional shift to the level of gesture analysis or a problem...
Multi-functional composite structures
Energy Technology Data Exchange (ETDEWEB)
Mulligan, Anthony C.; Halloran, John; Popovich, Dragan; Rigali, Mark J.; Sutaria, Manish P.; Vaidyanathan, K. Ranji; Fulcher, Michael L.; Knittel, Kenneth L.
2010-04-27
Fibrous monolith processing techniques to fabricate multifunctional structures capable of performing more than one discrete function such as structures capable of bearing structural loads and mechanical stresses in service and also capable of performing at least one additional non-structural function.
Multi-functional composite structures
Energy Technology Data Exchange (ETDEWEB)
Mulligan, Anthony C.; Halloran, John; Popovich, Dragan; Rigali, Mark J.; Sutaria, Manish P.; Vaidyanathan, K. Ranji; Fulcher, Michael L.; Knittel, Kenneth L.
2004-10-19
Fibrous monolith processing techniques to fabricate multifunctional structures capable of performing more than one discrete function such as structures capable of bearing structural loads and mechanical stresses in service and also capable of performing at least one additional non-structural function.
Beta Function and Anomalous Dimensions
DEFF Research Database (Denmark)
Pica, Claudio; Sannino, Francesco
2011-01-01
We demonstrate that it is possible to determine the coefficients of an all-order beta function linear in the anomalous dimensions using as data the two-loop coefficients together with the first one of the anomalous dimensions which are universal. The beta function allows to determine the anomalous...
INTERPOLATION BY LOOP'S SUBDIVISION FUNCTIONS
Institute of Scientific and Technical Information of China (English)
Guo-liang Xu
2005-01-01
For the problem of constructing smooth functions over arbitrary surfaces from discrete data, we propose to use Loop's subdivision functions as the interpolants. Results on the existence, uniqueness and error bound of the interpolants are established. An efficient progressive computation algorithm for the interpolants is also presented.
Functions in Biological Kind Classification
Lombrozo, Tania; Rehder, Bob
2012-01-01
Biological traits that serve functions, such as a zebra's coloration (for camouflage) or a kangaroo's tail (for balance), seem to have a special role in conceptual representations for biological kinds. In five experiments, we investigate whether and why functional features are privileged in biological kind classification. Experiment 1…
Functional programming through the curriculum
Thompson, Simon; Hill, Steve
1995-01-01
This paper discusses our experience in using a functional language in topics across the computer science curriculum. After examining the arguments for taking a functional approach, we look in detail at four case studies from different areas: programming language semantics, machine architectures, graphics and formal languages.
Functional genomics by mass spectrometry
DEFF Research Database (Denmark)
Andersen, Jens S.; Mann, M
2000-01-01
Systematic analysis of the function of genes can take place at the oligonucleotide or protein level. The latter has the advantage of being closest to function, since it is proteins that perform most of the reactions necessary for the cell. For most protein based ('proteomic') approaches to gene...
Asymptotic expansions of Jacobi functions
International Nuclear Information System (INIS)
The author presents an asymptotic expansion of the Jacobi polynomials which is based on the fact, that these polynomials are special hypergeometric functions. He uses an integral representation of these functions and expands the integrand in a power series. He derives explicit error bounds on this expansion. (HSI)
Correlation Functions and Power Spectra
DEFF Research Database (Denmark)
Larsen, Jan
2006-01-01
The present lecture note is a supplement to the textbook Digital Signal Processing by J. Proakis and D.G. Manolakis used in the IMM/DTU course 02451 Digital Signal Processing and provides an extended discussion of correlation functions and power spectra. The definitions of correlation functions...
Functional End Groups in Polytetrahydrofuran
Caroli, Giuseppe; Loos, Katja
2013-01-01
Polytetrahydrofuran (PTHF) is a very widespread polymer, which is used in numerous applications. Very frequently, its functional end groups play a key role, in that they are exploited to perform further reactions. However, only limited work is available to date on the preparation of functionalized P
Duality Unary Convex Functions Programming
Institute of Scientific and Technical Information of China (English)
朱德通
1993-01-01
Most nonliner programming problems consist of functions which are sums of unary convex functions of linear fuctions.In this paper,we derive the duality forms of the unary convex optimization,and these technuques are applied to the geometric programming and minimum discriminaiton information problems.
Function variational principles and coercivity
Turinici, Mihai
2005-04-01
The function type extension of Ekeland's variational principle [J. Math. Anal. Appl. 47 (1974) 324-353] due to Zhong [Nonlinear Anal. 29 (1997) 1421-1431] is deductible in a simplified manner and in a larger functional context. This is also true for his (normed) coercivity result, based on Palais-Smale techniques.
Decompositions of cascaded GMW functions
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
In this paper, the inner GMW-type factors of any shifted GMW function are determined. As a consequence, the criterion given in related work of Gong et al. for any two shifted GMW functions to be equal is re-obtained as a special case.
A Functional Hodrick Prescott Filter
Djehiche, Boualem; Nassar, Hiba
2013-01-01
We propose a functional version of the Hodrick-Prescott fi?lter for functional data which take values in an in?finite dimensional separable Hilbert space. We further characterize the associated optimal smoothing parameter when the associated linear operator is compact and the underlying distribution of the data is Gaussian.
Radial distribution function in polymers
Przygocki, Wladyslaw
1997-02-01
Radial distribution function is a very useful tool for determination of the polymer structure. The connection between the scattered X-ray intensity and radial distribution function is presented. Some examples of RDF for polyethylene and for poly(ethylene terephtalate).
Spectral characterization of abstract functions
International Nuclear Information System (INIS)
Let G be locally compact abelian group and GAMMA its dual group. Let X be locally convex complete space and X* its dual space. In this paper we give spectral characterization of bounded uniformly continuous functions from G to X. Also, we give applications to the characterization of solutions of functional differential equations. (author)
Functional Equations and Fourier Analysis
Yang, Dilian
2010-01-01
By exploring the relations among functional equations, harmonic analysis and representation theory, we give a unified and very accessible approach to solve three important functional equations -- the d'Alembert equation, the Wilson equation, and the d'Alembert long equation, on compact groups.
Gordon, Sheldon P.; Gordon, Florence S.
2010-01-01
One of the most important applications of the definite integral in a modern calculus course is the mean value of a function. Thus, if a function "f" is defined on an interval ["a", "b"], then the mean, or average value, of "f" is given by [image omitted]. In this note, we will investigate the meaning of other statistics associated with a function…
Cosmetic and Functional Nasal Deformities
... nasal complaints. Nasal deformity can be categorized as “cosmetic” or “functional.” Cosmetic deformity of the nose results in a less ... taste , nose bleeds and/or recurrent sinusitis . A cosmetic or functional nasal deformity may occur secondary to ...
Rho GTPase function in development
DEFF Research Database (Denmark)
Pedersen, Esben; Brakebusch, Cord
2012-01-01
Rho GTPase functions have been carefully investigated for many years using cell biological models. In recent years, mouse models with targeted mutations in Rho GTPase genes enabled the study of Rho GTPase function in vivo, partially confirming and partially contradicting expectations based on ear...
Incentives in Supply Function Equilibrium
DEFF Research Database (Denmark)
Vetter, Henrik
2014-01-01
The author analyses delegation in homogenous duopoly under the assumption that the firm-managers compete in supply functions. In supply function equilibrium, managers’ decisions are strategic complements. This reverses earlier findings in that the author finds that owners give managers incentives...
Chain functions and scoring functions in genetic networks.
Gat-Viks, I; Shamir, R
2003-01-01
One of the grand challenges of system biology is to reconstruct the network of regulatory control among genes and proteins. High throughput data, particularly from expression experiments, may gradually make this possible in the future. Here we address two key ingredients in any such 'reverse engineering' effort: The choice of a biologically relevant, yet restricted, set of potential regulation functions, and the appropriate score to evaluate candidate regulatory relations. We propose a set of regulation functions which we call chain functions, and argue for their ubiquity in biological networks. We analyze their complexity and show that their number is exponentially smaller than all boolean functions of the same dimension. We define two new scores: one evaluating the fitness of a candidate set of regulators of a particular gene, and the other evaluating a candidate function. Both scores use established statistical methods. Finally, we test our methods on experimental gene expression data from the yeast galactose pathway. We show the utility of using chain functions and the improved inference using our scores in comparison to several extant scores. We demonstrate that the combined use of the two scores gives an extra advantage. We expect both chain functions and the new scores to be helpful in future attempts to infer regulatory networks. PMID:12855446
Characterizing extremal coefficient functions and extremal correlation functions
Strokorb, Kirstin
2012-01-01
We focus on two dependency quantities of a max-stable random field $X$ on some space $T$: the extremal coefficient function $\\theta$ which we define on finite sets of $T$ and the extremal correlation function $\\chi(s,t)=\\lim_{x \\uparrow \\infty} \\PP(X_s \\geq x \\mid X_t \\geq x)$. We fully characterize extremal coefficient functions $\\theta$ by a property called complete alternation and construct a corresponding max-stable random field. Simple properties and consequences concerning the convex geometry of extremal coefficients are derived. We study how the continuity of $X$, $\\theta$ and $\\chi$ are linked to each other, and we show that extremal correlation functions $\\chi$ allow for convex combinations in general, and for products and pointwise limits if the resulting function is continuous. These are operations which are well-known for positive definite functions, but the latter are non-trivial for extremal correlation functions. Finally, we regard some additional implications, when the random field $X$ on $T=\\...
A functional perspective on personality.
Perugini, Marco; Costantini, Giulio; Hughes, Sean; De Houwer, Jan
2016-02-01
Personality psychology has made enormous progresses over the years by accumulating empirical evidence on how patterns of stable individual differences in behaviours can be clustered systematically at different levels of abstraction (i.e. traits and facets) and how they can predict important consequential outcomes. At the same time, functionally orientated researchers have accumulated a vast body of knowledge on environment-behaviour relations and the underlying behavioural principles, that is, abstract descriptions of the way in which behaviour is a function of elements in the past and present environment. We explore a functional perspective on personality that attempts to bridge the two domains and to exploit the best of both worlds. From this functional perspective, personality refers to the impact of the individual on different types of environment-behaviour relations as well as on the way other factors moderate those relations. We discuss the potential of this functional perspective on personality to organise existing scientific knowledge and inspire future research.
Normality Criteria of Meromorphic Functions
Institute of Scientific and Technical Information of China (English)
Wang Qiong; Yuan Wen-jun; Chen Wei; Tian Hong-gen
2016-01-01
In this paper, we consider normality criteria for a family of meromorphic functions concerning shared values. Let F be a family of meromorphic functions defined in a domain D, m, n, k and d be four positive integers satisfying m≥n+2 and d≥ k+1m−n−1 , and a(̸=0), b be two finite constants. Suppose that every f ∈F has all its zeros and poles of multiplicity at least k and d, respectively. If (fn)(k)−afm and (gn)(k)−agm share the value b for every pair of functions (f, g) of F, then F is normal in D. Our results improve the related theorems of Schwick (Schwick W. Normality criteria for families of meromorphic function. J. Anal. Math., 1989, 52:241–289), Li and Gu (Li Y T, Gu Y X. On normal families of meromorphic functions. J. Math. Anal. Appl., 2009, 354: 421–425).
A Generalized Cubic Functional Equation
Institute of Scientific and Technical Information of China (English)
P. K. SAHOO
2005-01-01
In this paper, we determine the general solution of the functional equation f1 (2x + y) +f2(2x - y) ＝ f3(x + y) + f4(x - y) + f5(x) without assuming any regularity condition on the unknown functions f1,f2,f3, f4,f5: R → R. The general solution of this equation is obtained by finding the general solution of the functional equations f(2x + y) + f(2x - y) = g(x + y) + g(x - y) + h(x) and f(2x + y) - f(2x - y) ＝ g(x + y) - g(x - y). The method used for solving these functional equations is elementary but exploits an important result due to Hosszu. The solution of this functional equation can also be determined in certain type of groups using two important results due to Székelyhidi.
Clinical evaluation of functional dysphonia.
Monday, L A
1983-10-01
Functional dysphonia is a voice impairment without any organic lesion of the phonating system. It may be classified into two categories: functional dysphonia itself where no lesions are found and functional laryngopathies where vocal cord lesions may be attributed to vocal abuse or misuse. The clinical evaluation of a dysphonic patient is performed in three steps: history taking, vocal evaluation, and examination. History taking helps the diagnosis and may be considered also as a therapeutic procedure. Vocal evaluation is oriented toward the voice itself and how it is produced. Then an ENT examination is performed with special attention to the larynx. In functional dysphonia, usually, everything looks normal but there may be signs of inflammation, hyperkinetism, hypokinetism, excessive laryngeal movements, etc. Functional laryngopathies include vocal nodules, laryngitis, polyps, and contact ulcer.
Asymptotic behavior of generalized functions
Pilipović, Stevan; Vindas, Jasson
2012-01-01
The asymptotic analysis has obtained new impulses with the general development of various branches of mathematical analysis and their applications. In this book, such impulses originate from the use of slowly varying functions and the asymptotic behavior of generalized functions. The most developed approaches related to generalized functions are those of Vladimirov, Drozhinov and Zavyalov, and that of Kanwal and Estrada. The first approach is followed by the authors of this book and extended in the direction of the S-asymptotics. The second approach — of Estrada, Kanwal and Vindas — is related to moment asymptotic expansions of generalized functions and the Ces'aro behavior. The main features of this book are the uses of strong methods of functional analysis and applications to the analysis of asymptotic behavior of solutions to partial differential equations, Abelian and Tauberian type theorems for integral transforms as well as for the summability of Fourier series and integrals. The book can be used by...
Cryptographic Boolean functions and applications
Cusick, Thomas W
2009-01-01
Boolean functions are the building blocks of symmetric cryptographic systems. Symmetrical cryptographic algorithms are fundamental tools in the design of all types of digital security systems (i.e. communications, financial and e-commerce).Cryptographic Boolean Functions and Applications is a concise reference that shows how Boolean functions are used in cryptography. Currently, practitioners who need to apply Boolean functions in the design of cryptographic algorithms and protocols need to patch together needed information from a variety of resources (books, journal articles and other sources). This book compiles the key essential information in one easy to use, step-by-step reference. Beginning with the basics of the necessary theory the book goes on to examine more technical topics, some of which are at the frontier of current research.-Serves as a complete resource for the successful design or implementation of cryptographic algorithms or protocols using Boolean functions -Provides engineers and scient...
The Conditional Sequence Information Function
Directory of Open Access Journals (Sweden)
Osman Guzide
2010-01-01
Full Text Available Problem statement: A great deal of attention has been given to the theory of information. It has found its applications in science especially in the area of Biothecnology. Previous studies on the subject has been limited to either conditional or sequence problem solving. This study combines both conditional and sequence properties of the information function. By doing this, researchers can find solutions to more problems that are applicable in real life. Approach: First, properties of the dynamical systems and the information function defined by Shannon has been provided, Then, the conditional sequence information function of a dynamical system together with its proof was presented. Result: This new function now exists now and ready for the use in many real life problems such as finding solutions to DNA sequence with conditional sickness. Conclusion: This new function created opens a new avenue to researches in solving more complex problems by using its developed properties.
Diagnostic Approach to Functional Recovery
DEFF Research Database (Denmark)
Havsteen, Inger; Madsen, Kristoffer H; Christensen, Hanne Krarup;
2013-01-01
to an acute ischemic lesion. Task-related as well as resting-state fMRI have been successfully applied to elucidate post-stroke remodeling of functional brain networks. This includes regional changes in neuronal activation as well as distributed changes in functional brain connectivity. Since fMRI is readily...... available and does not pose any adverse effects, repeated fMRI measurements provide unprecedented possibilities to prospectively assess the time course of reorganization in functional neural networks after stroke and relate the temporospatial dynamics of reorganization at the systems level to functional......, only up to 20-25% of patients are eligible to causal treatment. Further, care in a specialized stroke unit improves prognosis in all patients independent of age and stroke severity. Even when it is not possible to prevent tissue loss, the surviving brain areas of functional brain networks have...
Invariant probabilities of transition functions
Zaharopol, Radu
2014-01-01
The structure of the set of all the invariant probabilities and the structure of various types of individual invariant probabilities of a transition function are two topics of significant interest in the theory of transition functions, and are studied in this book. The results obtained are useful in ergodic theory and the theory of dynamical systems, which, in turn, can be applied in various other areas (like number theory). They are illustrated using transition functions defined by flows, semiflows, and one-parameter convolution semigroups of probability measures. In this book, all results on transition probabilities that have been published by the author between 2004 and 2008 are extended to transition functions. The proofs of the results obtained are new. For transition functions that satisfy very general conditions the book describes an ergodic decomposition that provides relevant information on the structure of the corresponding set of invariant probabilities. Ergodic decomposition means a splitting of t...
Fractal calculus involving gauge function
Golmankhaneh, Alireza K.; Baleanu, Dumitru
2016-08-01
Henstock-Kurzweil integral or gauge integral is the generalization of the Riemann integral. The functions which are not integrable because of singularity in the senses of Lebesgue or Riemann are gauge integrable. In this manuscript, we have generalized Fα-calculus using the gauge integral method for the integrating of the functions on fractal set subset of real-line where they have singularities. The suggested new method leads to the wider class of functions on the fractal subset of real-line that are *Fα-integrable. Using gauge function we define *Fα-derivative of functions their Fα-derivative is not exist. The reported results can be used for generalizing the fundamental theorem of Fα-calculus.
Functional images of the lungs
International Nuclear Information System (INIS)
The objective of ''functional imaging'' is to portray, in a single image, the relative function of various regions of an organ, or system of organs. The basic data on which such images are based are obtained from serial quantitative images of the organ's function (functions) obtained at various times after administering one or more radioactive tracers. The studies are carried out using the scintillation camera and 133Xe gas for measuring ventilation and a particulate agent such as sup(99m)Tc-labelled albumin microspheres for measuring regional perfusion. To measure regional ventilation, the patient is first allowed to breathe and equilibrate throughout his lungs xenon from a spirometer; he is then allowed to breathe normally room air which washes the xenon from his lungs. During equilibrium and washout, serial quantized image frames are recorded. To measure regional perfusion, the patient is administered sup(99m)Tc microspheres intravenously and a single image frame is recorded. From the serial images of the 133Xe washout frames, after spatial averaging, a parameter proportional to the washout times is computed for each image cell element. These washout parameters are then used to construct a ''ventilation functional image''. The spatial resolution of the study is adequate to provide structural as well as regional function information in a single image. The functional image provides an easily interpretable image of regional function that would be difficult to interpret if presented to the physician in the form of a mass of numerical data, or as a time sequence of multiple serial images. The functional image contains, in one image, all the information from the time serial images representing the washout of the radioactive gas. The ventilation and perfusion images can be combined in a single image by using colour. Use of colour is quite effective in viewing multiple functions and their spatial relations in the same image. (author)
Functional principal components analysis of workload capacity functions.
Burns, Devin M; Houpt, Joseph W; Townsend, James T; Endres, Michael J
2013-12-01
Workload capacity, an important concept in many areas of psychology, describes processing efficiency across changes in workload. The capacity coefficient is a function across time that provides a useful measure of this construct. Until now, most analyses of the capacity coefficient have focused on the magnitude of this function, and often only in terms of a qualitative comparison (greater than or less than one). This work explains how a functional extension of principal components analysis can capture the time-extended information of these functional data, using a small number of scalar values chosen to emphasize the variance between participants and conditions. This approach provides many possibilities for a more fine-grained study of differences in workload capacity across tasks and individuals. PMID:23475829
Source time-function as discriminant using empirical Green's function
Institute of Scientific and Technical Information of China (English)
HE Yongfeng; CHEN Xiaofei
2005-01-01
The source mechanism of underground nuclear explosions is remarkably different from that of earthquakes in both spatial radiation pattern and source time-function (STF). Small underground nuclear explosions can be used as empirical Green's functions (EGF) to isolate the source-time spectrum of a large suspected earthquake occurred in a Nuclear Test Site (target area) by the spectral division method. As this study shows, with high-quality data, the quotient spectrum can be transformed to the time domain, yielding the apparent far-field source-time function of the large suspected event. The relative source time-function (RSTF) of a nuclear explosion is usually a simple pulse with a duration of about 1 s., while an earthquake's is more complicated with a series of pulses and a longer duration. The RSTF can be used as a nice discriminant to distinguish the nature earthquakes from underground nuclear explosions in target areas.
Functional Abdominal Pain: "Get" the Function, Loose the Pain.
Draeger-Muenke, Reinhild
2015-07-01
Functional abdominal pain is a mind-body, psychosocial, and self-reinforcing experience with significant consequences for the sufferer and the surrounding support network. The occurrence of unpredictable symptoms and their severity add an element of dread and feeling out-of-control to daily life and often reduce overall functioning in a downward spiral. Two clinical presentations of functional abdominal pain are offered in this article (composites to protect confidentiality) dealing with abdominal pain syndrome and abdominal migraines. The treatment demonstrates the use of hypnotic principles for self-regulation, exploration, and meaning-making. Hypnosis treatment is conducted in combination with mindfulness-based interventions and Traditional Chinese Medicine's (TCM) teachings regarding abdominal health and illness. The clinical examples illustrate medical findings that suggest children with early life stress and an early onset of gastrointestinal somatization may not simply outgrow their functional abdominal pain but may suffer into adulthood. PMID:26046716
Intercepting Functions for Memoization: A Case Study Using Transcendental Functions
Suresh, Arjun; Narasimha Swamy, Bharath; Rohou, Erven; Seznec, André
2015-01-01
Memoization is the technique of saving result of executions so that future executions can be omitted when the input set repeats. Memoization has been proposed in previous literature at the instruction level, basic block level and function level using hardware as well as pure software level approaches including changes to programming language.In this paper, we focus on software memoization for procedural languages like C and Fortran, at the granularity of a function. We propose a simple linker...
Triebel, Hans
1992-01-01
Theory of Function Spaces II deals with the theory of function spaces of type Bspq and Fspq as it stands at the present. These two scales of spaces cover many well-known function spaces such as Hölder-Zygmund spaces, (fractional) Sobolev spaces, Besov spaces, inhomogeneous Hardy spaces, spaces of BMO-type and local approximation spaces which are closely connected with Morrey-Campanato spaces. Theory of Function Spaces II is self-contained, although it may be considered an update of the author’s earlier book of the same title. The book’s 7 chapters start with a historical survey of the subject, and then analyze the theory of function spaces in Rn and in domains, applications to (exotic) pseudo-differential operators, and function spaces on Riemannian manifolds. ------ Reviews The first chapter deserves special attention. This chapter is both an outstanding historical survey of function spaces treated in the book and a remarkable survey of rather different techniques developed in the last 50 years. It is s...
Spectral functions and transport coefficients from the functional renormalization group
Energy Technology Data Exchange (ETDEWEB)
Tripolt, Ralf-Arno
2015-06-03
In this thesis we present a new method to obtain real-time quantities like spectral functions and transport coefficients at finite temperature and density using the Functional Renormalization Group approach. Our non-perturbative method is thermodynamically consistent, symmetry preserving and based on an analytic continuation from imaginary to real time on the level of the flow equations. We demonstrate the applicability of this method by calculating mesonic spectral functions as well as the shear viscosity for the quark-meson model. In particular, results are presented for the pion and sigma spectral function at finite temperature and chemical potential, with a focus on the regime near the critical endpoint in the phase diagram of the quark-meson model. Moreover, the different time-like and space-like processes, which give rise to a complex structure of the spectral functions, are discussed. Finally, based on the momentum dependence of the spectral functions, we calculate the shear viscosity and the shear viscosity to entropy density ratio using the corresponding Green-Kubo formula.
2D Toda \\tau-functions as combinatorial generating functions
Guay-Paquet, Mathieu
2014-01-01
Two methods of constructing 2D Toda $\\tau$-functions that are generating functions for certain geometrical invariants of a combinatorial nature are related. The first involves generation of paths in the Cayley graph of the symmetric group $S_n$ by multiplication of the conjugacy class sums $C_\\lambda \\in C[S_n]$ in the group algebra by elements of an abelian group of central elements. Extending the characteristic map to the tensor product $C[S_n]\\otimes C[S_n]$ leads to double expansions in terms of power sum symmetric functions, in which the coefficients count the number of such paths. Applying the same map to sums over the orthogonal idempotents leads to diagonal double Schur function expansions that are identified as $\\tau$-functions of hypergeometric type. The second method is the standard construction of $\\tau$-functions as vacuum state matrix elements of products of vertex operators in a fermionic Fock space with elements of the abelian group of convolution symmetries. A homomorphism between these two g...
Functional Food Science in Europe.
Contor, L
2001-08-01
The goal of the Functional Food Science in Europe (FUFOSE) concerted action was to reach consensus on scientific concepts of functional foods in Europe by using the science base that supports evidence that specific nutrients positively affect physiological functions. The outcome proposes "a working definition" of functional foods: foods can be regarded as functional if they can be satisfactorily demonstrated to affect beneficially one or more target functions in the body, beyond adequate nutritional effects, in a way relevant to an improved state of health and well-being and/or reduction of risk of disease. Functional foods must remain foods and they must achieve their effects in amounts normally consumed in a diet. Evidence from human studies, based on markers relating to biological response or on intermediate endpoint markers of disease, could provide a sound scientific basis for messages and claims about the functional food products. Two types of claims are proposed that relate directly to these two categories of markers: Enhanced function claims (type A) and reduced risk of disease claims (type B). A new EU Concerted Action will start with, and build upon, the principles defined within FUFOSE. This project PASSCLAIM will (i) produce a consensus on principles for the scientific substantiation of health-related claims for food and food components, (ii) select common criteria for how markers should be identified, validated and used in well-designed studies to explore the links between diet and health and (iii) to evaluate critically the existing schemes which assess the scientific substantiation of claims.
Heavy quark fragmenting jet functions
International Nuclear Information System (INIS)
Heavy quark fragmenting jet functions describe the fragmentation of a parton into a jet containing a heavy quark, carrying a fraction of the jet momentum. They are two-scale objects, sensitive to the heavy quark mass, mQ, and to a jet resolution variable, τN. We discuss how cross sections for heavy flavor production at high transverse momentum can be expressed in terms of heavy quark fragmenting jet functions, and how the properties of these functions can be used to achieve a simultaneous resummation of logarithms of the jet resolution variable, and logarithms of the quark mass. We calculate the heavy quark fragmenting jet function GQQ at O(αs), and the gluon and light quark fragmenting jet functions into a heavy quark, GgQ and GlQ, at O(αs2). We verify that, in the limit in which the jet invariant mass is much larger than mQ, the logarithmic dependence of the fragmenting jet functions on the quark mass is reproduced by the heavy quark fragmentation functions. The fragmenting jet functions can thus be written as convolutions of the fragmentation functions with the matching coefficients Jij, which depend only on dynamics at the jet scale. We reproduce the known matching coefficients Jij at O(αs), and we obtain the expressions of the coefficients JgQ and JlQ at O(αs2). Our calculation provides all the perturbative ingredients for the simultaneous resummation of logarithms of mQ and τN
Various Shades of Blue's Functions
Janik, R A; Papp, G; Zahed, I; Janik, Romuald A.; Nowak, Maciej A.; Papp, Gabor; Zahed, Ismail
1997-01-01
We discuss random matrix models in terms of elementary operations on Blue's functions (functional inverse of Green's functions). We show that such operations embody the essence of a number of physical phenomena whether at/or away from the critical points. We illustrate these assertions by borrowing on a number of recent results in effective QCD in vacuum and matter. We provide simple physical arguments in favor of the universality of the continuum QCD spectral oscillations, whether at zero virtuality, in the bulk of the spectrum or at the chiral critical points. We also discuss effective quantum systems of disorder with strong or weak dissipation (Hatano-Nelson localization).
Functional units for natural numbers
Bergstra, J A
2009-01-01
Interaction with services provided by an execution environment forms part of the behaviours exhibited by instruction sequences under execution. Mechanisms related to the kind of interaction in question have been proposed in the setting of thread algebra. Like thread, service is an abstract behavioural concept. The concept of a functional unit is similar to the concept of a service, but more concrete. A state space is inherent in the concept of a functional unit, whereas it is not inherent in the concept of a service. In this paper, we establish the existence of a universal computable functional unit for natural numbers and related results.
Hypnosis for functional abdominal pain.
Gottsegen, David
2011-07-01
Chronic abdominal pain is a common pediatric condition affecting 20% of the pediatric population worldwide. Most children with this disorder are found to have no specific organic etiology and are given the diagnosis of functional abdominal pain. Well-designed clinical trials have found hypnotherapy and guided imagery to be the most efficacious treatments for this condition. Hypnotic techniques used for other somatic symptoms are easily adaptable for use with functional abdominal pain. The author discusses 2 contrasting hypnotic approaches to functional abdominal pain and provides implications for further research. These approaches may provide new insights into this common and complex disorder. PMID:21922712
Normal families of meromorphic functions
Institute of Scientific and Technical Information of China (English)
MA Chao-wei; WANG Yong-jun
2007-01-01
A normal theorem concerning meromorphic functions sharing values was proved with the method of Zalcman-Pang.The theorem is as follows.If for each f in F,all zeros of f-a have multiplicity at least k(k≥2),f and its k-th derivative function share a,and if f=b whenever its k-th denvative equal b,then F is normal in D.This theorem improved the result of Chen and Fang[Chen HH,Fang ML,Shared values and normal families of meromorphic functions,Journal of Mathematical Analysis and Applications,2001,260:124-1 32].
Accurate computation of Mathieu functions
Bibby, Malcolm M
2013-01-01
This lecture presents a modern approach for the computation of Mathieu functions. These functions find application in boundary value analysis such as electromagnetic scattering from elliptic cylinders and flat strips, as well as the analogous acoustic and optical problems, and many other applications in science and engineering. The authors review the traditional approach used for these functions, show its limitations, and provide an alternative ""tuned"" approach enabling improved accuracy and convergence. The performance of this approach is investigated for a wide range of parameters and mach
Crystal engineering using functionalized adamantane
Garcia, J. C.; Assali, L. V. C.; Machado, W. V. M.; Justo, J. F.
2010-08-01
We performed a first-principles investigation on the structural, electronic and optical properties of crystals made of chemically functionalized adamantane molecules. Several molecular building blocks, formed by boron and nitrogen substitutional functionalizations, were considered to build zinc blende and wurtzite crystals, and the resulting structures presented large bulk moduli and cohesive energies, wide and direct bandgaps, and low dielectric constants (low-κ materials). Those properties provide stability for such structures up to room temperature, superior to those of typical molecular crystals. This indicates a possible road map for crystal engineering using functionalized diamondoids, with potential applications ranging from space filling between conducting wires in nanodevices to nano-electromechanical systems.
Fragmentation Function in Thermofield Dynamics
Ladrem, M.; Chekerker, M.; Khanna, F. C.; Santana, A. E.
2013-04-01
The fragmentation function at high energy experiments is introduced by using thermofield dynamics (TFD), a real-time finite-temperature quantum field formalism. Due to the structure of TFD, the results at T = 0 and T ≠ 0 are split in a direct way. As an application, we consider the temperature effect on the fragmentation function of a hadron leading to quark-antiquark pairs. Using a definition of Wilson-loop in real-time, we find that the fragmentation function decreases in magnitude with an increase in the temperature.
Elliptic patching of harmonic functions
Giannotti, Cristina
2008-01-01
Given two harmonic functions $u_{+}(x,y)$, $u_{-}(x,y)$ defined on opposite sides of the $y$-axis in $\\mathbb{R}^2$ and periodic in $y$, we consider the problem of constructing a {\\it family of gluing elliptic functions}, i.e. a family of functions $u_{\\epsilon}(x,y)$ of class ${\\mathcal C}^{1,1}$ that coincide with $u_+$ and $u_-$ outside neighborhoods of the $y$-axis of width less than $\\epsilon$ and are solutions to linear, uniformly elliptic equations without zero order ...
Function spaces on local fields
Institute of Scientific and Technical Information of China (English)
SU; Weiyi; XU; Qiang
2006-01-01
We study the function spaces on local fields in this paper, such as Triebel Btype and F-type spaces, Holder type spaces, Sobolev type spaces, and so on, moreover,study the relationship between the p-type derivatives and the Holder type spaces. Our obtained results show that there exists quite difference between the functions defined on Euclidean spaces and local fields, respectively. Furthermore, many properties of functions defined on local fields motivate the new idea of solving some important topics on fractal analysis.
Zeta functions of quantum graphs
Harrison, J M
2009-01-01
Spectral problems on quantum graphs are a topic of current interest. Progress has been made with questions of spectral statistics, the spectral determinant, inverse problems, the relationship with operators on thin manifolds, Anderson localization, manipulation of the graph spectrum and many other important areas. In this article, however, we turn to a relatively untouched area of the spectral theory of quantum graphs and construct and analyze the spectral zeta function. Understanding the spectral zeta function has been a notable omission from the analysis of quantum graphs which is particularly striking as the Ihara-Selberg zeta function is known to play a fundamental role in the understanding of the spectral theory of combinatorial graphs and it is known that quantum and combinatorial graph spectra are related. In this article we construct zeta functions of quantum graphs using a contour integral technique based on the argument principle. We start by considering the special case of the star graph with Neuma...
Selective Functionalization of Tailored Nanostructures
Slingenbergh, Winand; Boer, Sanne K. de; Cordes, Thorben; Browne, Wesley R.; Feringa, Ben L.; Hoogenboom, Jacob P.; Hosson, Jeff Th.M. De; Dorp, Willem F. van
2012-01-01
The controlled positioning of nanostructures with active molecular components is of importance throughout nanoscience and nanotechnology. We present a novel three-step method to produce nanostructures that are selectively decorated with functional molecules. We use fluorophores and nanoparticles to
Functional Scaling of Musculoskeletal Models
DEFF Research Database (Denmark)
Lund, Morten Enemark; Andersen, Michael Skipper; de Zee, Mark;
specific to the patient. This is accomplished using optimisation methods to determine patient-specific joint positions and orientations, which minimise the least-squares error between model markers and the recorded markers from a motion capture experiment. Functional joint positions and joint axis...... orientations are then used to morph/scale a cadaver based musculoskeletal model using a set of radial basis functions (RBFs). Using the functional joint axes to scale musculoskeletal models provides a better fit to the marker data, and allows for representation of patients with considerable difference in bone...... geometry, without the need for MR/CT scans. However, more validation activities are needed to better understand the effect of morphing musculoskeletal models based on functional joint parameters....
Density functionals from deep learning
McMahon, Jeffrey M
2016-01-01
Density-functional theory is a formally exact description of a many-body quantum system in terms of its density; in practice, however, approximations to the universal density functional are required. In this work, a model based on deep learning is developed to approximate this functional. Deep learning allows computational models that are capable of naturally discovering intricate structure in large and/or high-dimensional data sets, with multiple levels of abstraction. As no assumptions are made as to the form of this structure, this approach is much more powerful and flexible than traditional approaches. As an example application, the model is shown to perform well on approximating the kinetic-energy density functional for noninteracting electrons. The model is analyzed in detail, and its advantages over conventional machine learning are discussed.
On Local Integrated Cosine Functions
Institute of Scientific and Technical Information of China (English)
SHI Jin-e; ZHENG Wei-xing
2001-01-01
Suppose X is a Banach space, and A is a closed operator. We give some equivalent conditions between A generating a local integrated cosine functions and the existence of solutions of abstract Cauchy problems.
Simple fixed functional space maintainer.
Goenka, Puneet; Sarawgi, Aditi; Marwah, Nikhil; Gumber, Parvind; Dutta, Samir
2014-01-01
Premature loss of a primary tooth is one of the most common etiology for malocclusion. Space maintainers are employed to prevent this complication. In anterior region, esthetics is an important concern along with function and space management. Fiber-reinforced composite (FRC) retained space maintainer solves all these purposes ef ficiently and ef fectively. In addition, the technique is simple and the appliance is very comfortable inside the oral cavity. Here is a case of premature loss of anterior primary tooth which was replaced by FRC retained esthetic functional space maintainer. The appliance was found to be functioning satisfactorily inside the oral cavity till the last visit (1 Year). How to cite this article: Goenka P, Sarawgi A, Marwah N, Gumber P, Dutta S. Simple Fixed Functional Space Maintainer. Int J Clin Pediatr Dent 2014;7(3):225-228.
Belowground biodiversity and ecosystem functioning
Bardgett, R.D.; Putten, van der W.H.
2014-01-01
Evidence is mounting that the immense diversity of microorganisms and animals that live belowground contributes significantly to shaping aboveground biodiversity and the functioning of terrestrial ecosystems. Our understanding of how this belowground biodiversity is distributed, and how it regulates
Functionalized silica materials for electrocatalysis
Indian Academy of Sciences (India)
Vellaichamy Ganesan
2015-02-01
Electrocatalysis is an important phenomenon which is utilized in metal–air batteries, fuel cells, electrochemical sensors, etc. To increase the efficiency of the electrocatalytic process and to increase the electrochemical accessibility of the immobilized electrocatalysts, functionalized and non-functionalized mesoporous organo-silica (MCM41-type-materials) are used in this study. These materials possess several suitable properties to be durable catalysts and/or catalyst supports. Owing to the uniform dispersion of electrocatalysts (metal complex and/or metal nanoparticles (NPs)) on the functionalized and non-functionalized silica, an enormous increase in the redox current is observed. Long range channels of silica materials with pore diameter of 15–100 Å allowed metal NPs to accommodate in a specified manner in addition to other catalysts. The usefulness of MCM-41-type silica in increasing the efficiency of electrocatalysisis demonstrated by selecting oxygen, carbon dioxide and nitrite reduction reactions as examples
Sexual function after transvaginal cholecystectomy
DEFF Research Database (Denmark)
Donatsky, Anders M; Jørgensen, Lars N; Meisner, Søren;
2014-01-01
INTRODUCTION: Despite several benefits, patients are concerned that transvaginal cholecystectomy has a negative impact on sexual health. The objective of this systematic review was to assess the impact of transvaginal cholecystectomy on postoperative dyspareunia and sexual function. METHOD: A...... literature search was performed in the PubMed and EMBASE databases. Papers reporting on postoperative dyspareunia, vaginal pain or discomfort, and sexual function were included. RESULTS: Seventeen papers reported on dyspareunia and vaginal pain or discomfort. Two papers reported a rate of de novo dyspareunia...... of 3.8% and 12.5%, respectively. One study reported a nonsignificant reduction in painful sexual intercourse and the remaining 14 reported no incidents of dyspareunia. Eight papers reported on sexual function. One paper using a nonvalidated questionnaire found impaired sexual function. The papers...
Functional neuroimaging of sleep disorders
International Nuclear Information System (INIS)
Sleep disorders may affect the health and normal life of human badly. However, the pathophysiology underlying adult sleep disorders is still unclear. Functional neuroimaging can be used to investigate whether sleep disorders are associated with specific changes in brain structure or regional activity. This paper reviews functional brain imaging findings in major intrinsic sleep disorders (i.e., idiopathic insomnia, narcolepsy, and obstructive sleep apnea) and in abnormal motor behavior during sleep (i.e., periodic limb movement disorder and REM sleep behavior disorder). Metabolic/functional investigations (positron emission tomography, single photon emission computed tomography, functional magnetic resonance imaging) are mainly reviewed, as well as neuroanatomical assessments (voxel-based morphometry, magnetic resonance spectroscopy). Meanwhile, here are some brief introduction of different kinds of sleep disorders. (authors)
Functional aspects of protein flexibility
DEFF Research Database (Denmark)
Teilum, Kaare; Olsen, Johan G; Kragelund, Birthe B
2009-01-01
Proteins are dynamic entities, and they possess an inherent flexibility that allows them to function through molecular interactions within the cell, among cells and even between organisms. Appreciation of the non-static nature of proteins is emerging, but to describe and incorporate...... this into an intuitive perception of protein function is challenging. Flexibility is of overwhelming importance for protein function, and the changes in protein structure during interactions with binding partners can be dramatic. The present review addresses protein flexibility, focusing on protein-ligand interactions....... The thermodynamics involved are reviewed, and examples of structure-function studies involving experimentally determined flexibility descriptions are presented. While much remains to be understood about protein flexibility, it is clear that it is encoded within their amino acid sequence and should be viewed...
Special Functions for Applied Scientists
Mathai, A M
2008-01-01
Special Functions for Applied Scientists provides the required mathematical tools for researchers active in the physical sciences. The book presents a full suit of elementary functions for scholars at the PhD level and covers a wide-array of topics and begins by introducing elementary classical special functions. From there, differential equations and some applications into statistical distribution theory are examined. The fractional calculus chapter covers fractional integrals and fractional derivatives as well as their applications to reaction-diffusion problems in physics, input-output analysis, Mittag-Leffler stochastic processes and related topics. The authors then cover q-hypergeometric functions, Ramanujan's work and Lie groups. The latter half of this volume presents applications into stochastic processes, random variables, Mittag-Leffler processes, density estimation, order statistics, and problems in astrophysics. Professor Dr. A.M. Mathai is Emeritus Professor of Mathematics and Statistics, McGill ...
Remote functionalization through alkene isomerization
Vasseur, Alexandre; Bruffaerts, Jeffrey; Marek, Ilan
2016-03-01
Exploiting the reactivity of one functional group within a molecule to generate a reaction at a different position is an ongoing challenge in organic synthesis. Effective remote functionalization protocols have the potential to provide access to almost any derivatives but are difficult to achieve. The difficulty is more pronounced for acyclic systems where flexible alkyl chains are present between the initiating functional group and the desired reactive centres. In this Review, we discuss the concept of remote functionalization of alkenes using metal complexes, leading to a selective reaction at a position distal to the initial double bond. We aim to show the vast opportunity provided by this growing field through selected and representative examples. Our aim is to demonstrate that using a double bond as a chemical handle, metal-assisted long-distance activation could be used as a powerful synthetic strategy.
Emotional Profile and Intellectual Functioning
Directory of Open Access Journals (Sweden)
Marianna Alesi
2015-07-01
Full Text Available Insufficient literature has been produced addressing children with borderline intellectual functioning (BIF and gifted intellectual functioning (GIF. The goal of this work is to compare levels of self-esteem, depression, anxiety at school, and insecurity among children with BIF and GIF, and a control group of average intellectual functioning (AIF. There were participants of 104 children (fourth grade of primary school. Analyses revealed that children with BIF showed a lower level of self-esteem and higher levels of depression and school anxiety. Moreover, our findings highlight the co-occurrence of school anxiety, depressed mood, and insecurity among the BIF and AIF groups. One of the issues that emerge from this study is the need to implement prevention programs aimed at identifying children with lower or higher levels of intellectual functioning. These findings highlight the importance of establishing what the most appropriate educational and clinical interventions are in reducing the risks of mental disorders in this population.
Pulmonary Function Testing in Children
... are s pirometry and airway resistance tests . What is spirometry? Spirometry is the most common lung function test done. ... follow very specific instructions. Most children can do spirometry by age 6, though some preschoolers are able ...
Teacher Praise: A Functional Analysis.
Brophy, Jere
1981-01-01
Teacher praise typically does not function as a reinforcer. Rather, it is reactive to and under the control of student behavior. Its effects must be understood using concepts from attribution and social learning/reinforcement theories. (Author/GK)
Functions Of Land Administration System
Oksana Sakal
2012-01-01
The theoretical basis and essence of some common and specific functions of land administration system as an integral mechanism of effective land use and land administration levels (case-study for forest and other land available for afforestation) are analysed.
Some Anisotropic Viscoelastic Green Functions
Bretin, Elie
2011-01-01
In this paper, we compute the closed form expressions of elastody- namic Green functions for three different viscoelastic media with simple type of anisotropy. We follow Burridge et al. [Proc. Royal Soc. of London. 440(1910): (1993)] to express unknown Green function in terms of three scalar functions $\\phi_i$, by using the spectral decomposition of the Christoffel tensor associated with the medium. The problem of computing Green function is, thus reduced to the resolution of three scalar wave equations satisfied by $\\phi_i$, and subsequent equations with $\\phi_i$ as source terms. To describe viscosity effects, we choose an empirical power law model which becomes well known Voigt model for quadratic frequency losses.
... Risks Links Related Topics Asthma COPD How the Lungs Work Idiopathic Pulmonary Fibrosis Sarcoidosis Send a link to ... mun-ary) function tests, measure how well your lungs work. These tests are used to look for the ...
Unitarity Corrections and Structure Functions
Gay-Ducati, M B
2002-01-01
We have studied the color dipole picture for the description of the deep inelastic process, mainly the structure functions which are driven directly by the gluon distribution. Estimates for those functions are obtained using the effective dipole cross section given by the Glauber-Mueller approach in QCD, encoding the corrections due to the unitarity effects associated with the saturation phenomenon. Frame invariance is verified in the calculations of the observables when analysing the experimental data.
Inductance and hypergeometric functions. II
DEFF Research Database (Denmark)
Karlsson, Per W.
2000-01-01
A previously obtained integral for the self-inductance of a solenoid is further transformed. The resulting formula involves double Kampé de Fériet functions which are analytic continuations rather than power series.......A previously obtained integral for the self-inductance of a solenoid is further transformed. The resulting formula involves double Kampé de Fériet functions which are analytic continuations rather than power series....
DYADIC METHOD FOR TENSOR FUNCTIONS
Institute of Scientific and Technical Information of China (English)
黄永念; 鲁昊
2002-01-01
In this paper, we discuss tensor functions by dyadic representation of tensor. Two different cases of scalar invariants and two different cases of tensor invariants are calculated. It is concluded that there are six independent scale invariants for a symmetrical tensor and an antisymmetrical tensor, and there are twelve invariants for two symmetrical tensors and an antisymmetrical tensor. And we present a new list of tensor invariants for the tensor-valued isotropic function.
Personality functioning and psychotherapy outcome
Lindfors, Olavi
2014-01-01
Personality functioning and psychotherapy outcome Personality dysfunction is manifested in interpersonal interactions and self-concept. It generates vulnerability to psychopathology and increases the risk of recurring symptoms and impaired work ability. Change in personality functioning is considered a major goal of psychotherapy, but published studies comparing different psychotherapeutic treatments on the subject are scarce. Likewise, the suitability of short-term and long-term therapy...
Executive functions in elderly men
Liu, Mu-En; Chang, Yun-Hsuan; Ku, Yan-Chiou; Lee, Sheng-Yu; Huang, Chih-Chung; Chen, Shiou-Lan; Chen, Shih-Heng; Chu, Chun-Hsien; Liu, Wen-Chien; Lu, Ru-Band
2011-01-01
The executive function deficit is greater in depressed patients with cardiovascular disease than in depressed patients without cardiovascular disease. Late-life depression is said to have a vascular etiology and would worsen the executive function. A cross-sectional design was used for this study. The study was done in outpatient clinics of Kaohsiung Veterans General Hospital and National Cheng Kung University Hospital, Taiwan. Three hundred thirty-five older elderly men (>75 years old) were ...
Function Concepts for Machine Parts
DEFF Research Database (Denmark)
Mortensen, Niels Henrik
1999-01-01
The majority of resources, like time and costs, consumed in industrial product development can be related to detailed design, i.e. the materialisation of machine parts (German Maschinenteile). Existing design theories based on a systems approach, e.g. Haberfellner [5] all have function, i...... to be identification of a purposeful behaviour concept, i.e. function for a machine part. The contribution is based on the theory of technical systems, Hubka and the domain theory, Andreasen....
Pulmonary function in Parkinson's disease.
Hovestadt, A.; Bogaard, J. M.; Meerwaldt, J D; van der Meché, F G; Van Stigt, J.
1989-01-01
Pulmonary function was investigated in 31 consecutive patients with relatively severe Parkinson's disease. Clinical disability was assessed by Hoehn and Yahr scale, Northwestern University Disability Scale and Websterscore. All patients were on levodopa substitution therapy and used anticholinergics. Pulmonary function was investigated by spirography, determination of a maximal inspiratory and expiratory flow-volume curve and, when possible, maximal static mouth pressures were determined. Pea...
Promiscuous enzymes from functional metagenomics
Colin, Pierre-Yves; Kintses, Balint; Gielen, Fabrice; Miton, Charlotte; Fischer, Gerhard; Mahomed, Mark; HYVONEN, Marko; Morgavi, Diego P.; Janssen, Dick B.; Hollfelder, Florian
2015-01-01
Unculturable bacterial communities provide a rich source of biocatalysts, but their experimental discovery by functional metagenomics is difficult, because the odds are stacked against the experimentor. Here we demonstrate functional screening of a million-membered metagenomic library in microfluidic picolitre droplet compartments. Using bait substrates, new hydrolases for sulfate monoesters and phosphotriesters were identified, mostly based on promiscuous activities presumed not to be under ...
Securitization and bank intermediation function
Zagonov, Maxim
2011-01-01
The move from the originate-to-hold to originate-to-distribute model of lending profoundly transformed the functioning of credit markets and weakened the natural asset transformation function performed by financial intermediaries for centuries. This shift also compromised the role of banks in channeling monetary policy initiatives, and undermined the importance of traditional asset-liability practices of interest rate risk management. The question is, therefore, whether securitisation is cond...
Optogenetic dissection of amygdala functioning
LaLumiere, Ryan T
2014-01-01
Studies of amygdala functioning have occupied a significant place in the history of understanding how the brain controls behavior and cognition. Early work on the amygdala placed this small structure as a key component in the regulation of emotion and affective behavior. Over time, our understanding of its role in brain processes has expanded, as we have uncovered amygdala influences on memory, reward behavior, and overall functioning in many other brain regions. Studies have indicated that t...
Occupation numbers from functional integral
Wetterich, C.
2007-01-01
Occupation numbers for non-relativistic interacting particles are discussed within a functional integral formulation. We concentrate on zero temperature, where the Bogoliubov theory breaks down for strong couplings as well as for low dimensional models. We find that the leading behavior of the occupation numbers for small momentum is governed by a quadratic time derivative in the inverse propagator that is not contained in the Bogoliubov theory. We propose to use a functional renormalization ...
Implied Volatility Functions: Empirical Tests
Dumas, Bernard J; Fleming, Jeff; Robert E. Whaley
1996-01-01
Black and Scholes (1973) implied volatilities tend to be systematically related to the option's exercise price and time to expiration. Derman and Kani (1994), Dupire (1994), and Rubinstein (1994) attribute this behavior to the fact that the Black-Scholes constant volatility assumption is violated in practice. These authors hypothesize that the volatility of the underlying asset's return is a deterministic function of the asset price and time and develop the deterministic volatility function (...
Statistical Challenges in Functional Genomics
Sebastiani, Paola; Gussoni, Emanuela; Kohane, Isaac S.; Ramoni, Marco F
2003-01-01
On February 12, 2001 the Human Genome Project announced the completion of a draft physical map of the human genome---the genetic blueprint for a human being. Now the challenge is to annotate this map by understanding the functions of genes and their interplay with proteins and the environment to create complex, dynamic living systems. This is the goal of functional genomics. Recent technological advances enable biomedical investigators to observe the genome of entire orga...
GRID INFORMATION SECURITY FUNCTIONAL REQUIREMENT
Amy Poh Ai Ling; Mukaidono Masao
2011-01-01
This paper describes the background of smart information infrastructure and the needs for smart grid information security. It introduces the conceptual analysis to the methodology with the application ofhermeneutic circle and information security functional requirement identification. Information security for the grid market cover matters includes automation and communications industry that affects the operation of electric power systems and the functioning of the utilities that manage them ...
Selective functionalization of carbon nanotubes
Strano, Michael S. (Inventor); Usrey, Monica (Inventor); Barone, Paul (Inventor); Dyke, Christopher A. (Inventor); Tour, James M. (Inventor); Kittrell, W. Carter (Inventor); Hauge, Robert H. (Inventor); Smalley, Richard E. (Inventor)
2009-01-01
The present invention is directed toward methods of selectively functionalizing carbon nanotubes of a specific type or range of types, based on their electronic properties, using diazonium chemistry. The present invention is also directed toward methods of separating carbon nanotubes into populations of specific types or range(s) of types via selective functionalization and electrophoresis, and also to the novel compositions generated by such separations.
Operational calculus and generalized functions
Erdelyi, Arthur
2013-01-01
This brief monograph by a distinguished professor is based on a mathematics course offered at the California Institute of Technology. The majority of students taking this course were advanced undergraduates and graduate students of engineering. A solid background in advanced calculus is a prerequisite.Topics include elementary and convergence theories of convolution quotients, differential equations involving operator functions, and exponential functions of operators. Tools developed in the preceding chapters are then applied to problems in partial differential equations. Solutions to selected
Functional Foods as Differentiated Products
Bonanno, Alessandro
2009-01-01
Food products providing health benefits beyond nutrition, or functional foods, draw consumers’ attention and promise growth opportunities for innovator food manufacturers. European functional food manufacturers may be facing future challenges, mainly due to the European Union Regulation (EC) No.1924/2006 regulating food products’ health-claims. However, in spite of the interest shown by academics to understand the acceptance of these products no study exists that analyzes the profitability of...
Drug treatment of functional dyspepsia
Institute of Scientific and Technical Information of China (English)
Klaus M(o)nkemüller; Peter Malfertheiner
2006-01-01
Symptomatic improvement of patients with functional dyspepsia after drug therapy is often incomplete and obtained in not more than 60% of patients. This is likely because functional dyspepsia is a heterogeneous disease.Although great advance has been achieved with the consensus definitions of the Rome Ⅰ and Ⅱ criteria, there are still some aspects about the definition of functional dyspepsia that require clarification. The Rome criteria explicitly recognise that epigastric pain or discomfort must be the predominant complaint in patients labelled as suffering from functional dyspepsia. However, this strict definition can create problems in the daily primary care clinical practice, where the patient with functional dyspepsia presents with multiple symptoms. Before starting drug therapy it is recommended to provide the patient with an explanation of the disease process and reassurance. A thorough physical examination and judicious use of laboratory data and endoscopy are also indicated. In general, the approach to treat patients with functional dyspepsia based on their main symptom is practical and effective. Generally, patients should be treated with acid suppressive therapy using proton-pump inhibitors if the predominant symptoms are epigastric pain or gastroesophageal reflux symptoms. Although the role of Helicobacter pylori(H pylori) in functional dyspepsia continues to be a matter of debate, recent data indicate that there is modest but clear benefit of eradication of H pylori in patients with functional dyspepsia. In addition,H pylori is a gastric carcinogen arid if found it should be eliminated. Although there are no specific diets for patients with FD, it may be helpful to guide the patients on healthy exercise and eating habits.
What dentition assures oral function?
DEFF Research Database (Denmark)
Gotfredsen, Klaus; Walls, Angus W G
2007-01-01
OBJECTIVE: To evaluate the relationship between dentition and oral function. MATERIAL AND METHODS: A search of the English literature was undertaken using PubMed and appropriate keywords. Citations were identified and hand sorted to confirm their validity against our inclusion criteria. Four spec...... for the year 2000, namely to maintain a natural dentition of not less than 20 teeth throughout life, is substantiated by the current literature review as this proposed dentition will assure an acceptable level of oral function....
Functional brain mapping of psychopathology
Honey, G.; Fletcher, P.; BULLMORE, E.
2002-01-01
In this paper, we consider the impact that the novel functional neuroimaging techniques may have upon psychiatric illness. Functional neuroimaging has rapidly developed as a powerful tool in cognitive neuroscience and, in recent years, has seen widespread application in psychiatry. Although such studies have produced evidence for abnormal patterns of brain response in association with some pathological conditions, the core pathophysiologies remain unresolved. Although imaging techniques provi...
Formalism and functionalism in linguistics.
Newmeyer, Frederick J
2010-05-01
Formalism and functionalism in linguistics are often taken to be diametrically opposed approaches. However, close examination of the relevant phenomena reveals that the two are complementary, rather than being irrevocably in opposition to each other. One can be a formal linguist and a functional linguist at the same time, without there being any contradiction. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.
Gastrointestinal function development and microbiota
Di Mauro, Antonio; Neu, Josef; Riezzo, Giuseppe; Raimondi, Francesco; Martinelli, Domenico; Francavilla, Ruggiero; Indrio, Flavia
2013-01-01
The intestinal microbiota plays an important role in the development of post-natal gastrointestinal functions of the host. Recent advances in our capability to identify microbes and their function offer exciting opportunities to evaluate the complex cross talk between microbiota, intestinal barrier, immune system and the gut-brain axis. This review summarizes these interactions in the early colonization of gastrointestinal tract with a major focus on the role of intestinal microbiota in the p...
Functional imaging for regenerative medicine
Leahy, Martin; Thompson, Kerry; Zafar, Haroon; Alexandrov, Sergey; Foley, Mark; O’Flatharta, Cathal; Dockery, Peter
2016-01-01
In vivo imaging is a platform technology with the power to put function in its natural structural context. With the drive to translate stem cell therapies into pre-clinical and clinical trials, early selection of the right imaging techniques is paramount to success. There are many instances in regenerative medicine where the biological, biochemical, and biomechanical mechanisms behind the proposed function of stem cell therapies can be elucidated by appropriate imaging. Imaging techniques can...
Functional models for Nevanlinna families
Directory of Open Access Journals (Sweden)
Jussi Behrndt
2008-01-01
Full Text Available The class of Nevanlinna families consists of \\(\\mathbb{R}\\-symmetric holomorphic multivalued functions on \\(\\mathbb{C} \\setminus \\mathbb{R}\\ with maximal dissipative (maximal accumulative values on \\(\\mathbb{C}_{+}\\ (\\(\\mathbb{C}_{-}\\, respectively and is a generalization of the class of operator-valued Nevanlinna functions. In this note Nevanlinna families are realized as Weyl families of boundary relations induced by multiplication operators with the independent variable in reproducing kernel Hilbert spaces.
Cardiopulmonary function and laparoscopic cholecystectomy.
Wahba, R W; Béïque, F; Kleiman, S J
1995-01-01
This review analyzes the literature dealing with cardiopulmonary function during and pulmonary function following laparoscopic cholecystectomy in order to describe the patterns of changes in these functions and the mechanisms involved as well as to identify areas of concern and lacunae in our knowledge. Information was obtained from a Medline literature search and the annual meeting supplements of Anesthesiology, Anesth Analg, Br J Anaesth, and Can J Anaesth. The principal findings were that changes in cardiovascular function due to the insufflation are characterized by an immediate decrease in cardiac index and an increase in mean arterial blood pressure and systemic vascular resistance. In the next few minutes there is partial restoration of cardiac index and resistance but blood pressure and heart rate do not change. The pattern is the result of the interaction between increased abdominal pressure, neurohumoral responses and absorbed CO2. Pulmonary function changes are characterized by reduced compliance without large alterations in PaO2, but tissue oxygenation can be adversely affected due to reduced O2 delivery. A major difficulty in maintaining normocarbia is due to the abdominal distention reducing pulmonary compliance and to CO2 absorption. End tidal CO2 tension is not a reliable index of PaCO2, particularly in ASA III-IV patients. The pattern of lung function following LC is characterized by a transient reduction in lung volumes and capacities with a restrictive breathing pattern and the loss of the abdominal contribution to breathing. Atelectasis also occurs. These changes are qualitatively similar to but of a lesser magnitude than those following "open" abdominal operations. It is concluded that the changes in cardiopulmonary function during laparoscopic upper abdominal surgery lead us to suggest judicious invasive monitoring and careful interpretation in ASA III-IV patients. Lung function following extensive procedures in sick patients has not been
Normal Functions Concerning Shared Values
Institute of Scientific and Technical Information of China (English)
WANG XIAO-JING
2009-01-01
In this paper we discuss normal functions concerning shared values. We obtain the follow result. Let F be a family of meromorphic functions in the unit disc △, and a be a nonzero finite complex number. If for any f ∈ F, the zeros of f are of multiplicity, f and f' share a, then there exists a positive number M such that for any f ∈ F, (1 -|z|~2)(|f'(z)|)/(1+|f(z)|~2)≤ M.
Functional neuroimaging and childhood autism
Energy Technology Data Exchange (ETDEWEB)
Boddaert, Nathalie [Service de Radiologie Pediatrique, Necker-Enfants Malades Hospital, Paris (France); Service Hospitalier Frederic Joliot, DRM, DSV, CEA, Orsay (France); Zilbovicius, Monica [Service Hospitalier Frederic Joliot, DRM, DSV, CEA, Orsay (France); INSERM, Tours (France)
2002-01-01
Childhood autism is now widely viewed as being of developmental neurobiological origin. Yet, localised structural and functional brain correlates of autism have to be established. Structural brain-imaging studies performed in autistic patients have reported abnormalities such as increased total brain volume and cerebellar abnormalities. However, none of these abnormalities fully account for the full range of autistic symptoms. Functional brain imaging, such as positron emission tomography (PET), single photon emission computed tomography (SPECT) and functional MRI (fMRI) have added a new perspective to the study of normal and pathological brain functions. In autism, functional studies have been performed at rest or during activation. However, first-generation functional imaging devices were not sensitive enough to detect any consistent dysfunction. Recently, with improved technology, two independent groups have reported bilateral hypoperfusion of the temporal lobes in autistic children. In addition, activation studies, using perceptive and cognitive paradigms, have shown an abnormal pattern of cortical activation in autistic patients. These results suggest that different connections between particular cortical regions could exist in autism. The purpose of this review is to present the main results of rest and activation studies performed in autism. (orig.)
Functional neuroimaging and childhood autism
International Nuclear Information System (INIS)
Childhood autism is now widely viewed as being of developmental neurobiological origin. Yet, localised structural and functional brain correlates of autism have to be established. Structural brain-imaging studies performed in autistic patients have reported abnormalities such as increased total brain volume and cerebellar abnormalities. However, none of these abnormalities fully account for the full range of autistic symptoms. Functional brain imaging, such as positron emission tomography (PET), single photon emission computed tomography (SPECT) and functional MRI (fMRI) have added a new perspective to the study of normal and pathological brain functions. In autism, functional studies have been performed at rest or during activation. However, first-generation functional imaging devices were not sensitive enough to detect any consistent dysfunction. Recently, with improved technology, two independent groups have reported bilateral hypoperfusion of the temporal lobes in autistic children. In addition, activation studies, using perceptive and cognitive paradigms, have shown an abnormal pattern of cortical activation in autistic patients. These results suggest that different connections between particular cortical regions could exist in autism. The purpose of this review is to present the main results of rest and activation studies performed in autism. (orig.)
Boolean networks with veto functions
Ebadi, Haleh; Klemm, Konstantin
2014-08-01
Boolean networks are discrete dynamical systems for modeling regulation and signaling in living cells. We investigate a particular class of Boolean functions with inhibiting inputs exerting a veto (forced zero) on the output. We give analytical expressions for the sensitivity of these functions and provide evidence for their role in natural systems. In an intracellular signal transduction network [Helikar et al., Proc. Natl. Acad. Sci. USA 105, 1913 (2008), 10.1073/pnas.0705088105], the functions with veto are over-represented by a factor exceeding the over-representation of threshold functions and canalyzing functions in the same system. In Boolean networks for control of the yeast cell cycle [Li et al., Proc. Natl. Acad. Sci. USA 101, 4781 (2004), 10.1073/pnas.0305937101; Davidich et al., PLoS ONE 3, e1672 (2008), 10.1371/journal.pone.0001672], no or minimal changes to the wiring diagrams are necessary to formulate their dynamics in terms of the veto functions introduced here.
Differential Subordinations for Nonanalytic Functions
Directory of Open Access Journals (Sweden)
Georgia Irina Oros
2014-01-01
Full Text Available In the paper by Mocanu (1980, Mocanu has obtained sufficient conditions for a function in the classes C1(U, respectively, and C2(U to be univalent and to map U onto a domain which is starlike (with respect to origin, respectively, and convex. Those conditions are similar to those in the analytic case. In the paper by Mocanu (1981, Mocanu has obtained sufficient conditions of univalency for complex functions in the class C1 which are also similar to those in the analytic case. Having those papers as inspiration, we try to introduce the notion of subordination for nonanalytic functions of classes C1 and C2 following the classical theory of differential subordination for analytic functions introduced by Miller and Mocanu in their papers (1978 and 1981 and developed in their book (2000. Let Ω be any set in the complex plane C, let p be a nonanalytic function in the unit disc U, p∈C2(U, and let ψ(r,s,t;z:C3×U→C. In this paper, we consider the problem of determining properties of the function p, nonanalytic in the unit disc U, such that p satisfies the differential subordination ψ(p(z,Dp(z,D2p(z-Dp(z;z⊂Ω⇒p(U⊂Δ.
Elementary Functions, Student's Text, Unit 21.
Allen, Frank B.; And Others
Unit 21 in the SMSG secondary school mathematics series is a student text covering the following topics in elementary functions: functions, polynomial functions, tangents to graphs of polynomial functions, exponential and logarithmic functions, and circular functions. Appendices discuss set notation, mathematical induction, significance of…
Fold modulating function: Bacterial toxins to functional amyloids
Directory of Open Access Journals (Sweden)
Adnan Khawaja Syed
2014-08-01
Full Text Available Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is well known that environmental factors control toxin expression, however recent work suggests that some bacteria manipulate the fold of these protein toxins to control their function. The β-sheet rich amyloid fold is a highly stable ordered aggregate that many toxins form in response to specific environmental conditions. When in the amyloid state, toxins become inert, losing the cytolytic activity they display in the soluble form. Emerging evidence suggest that some amyloids function as toxin storage systems until they are again needed, while other bacteria utilize amyloids as a structural matrix component of biofilms. This amyloid matrix component facilitates resistance to biofilm disruptive challenges. The bacterial amyloids discussed in this review reveal an elegant system where changes in protein fold and solubility dictate the function of proteins in response to the environment.
Singular and Plural Functions for Functional Logic Programming
Riesco, Adrián
2012-01-01
Functional logic programming (FLP) languages use non-terminating and non-confluent constructor systems (CS's) as programs in order to define non-strict non-determi-nistic functions. Two semantic alternatives have been usually considered for parameter passing with this kind of functions: call-time choice and run-time choice. While the former is the standard choice of modern FLP languages, the latter lacks some properties---mainly compositionality---that have prevented its use in practical FLP systems. Traditionally it has been considered that call-time choice induces a singular denotational semantics, while run-time choice induces a plural semantics. We have discovered that this latter identification is wrong when pattern matching is involved, and thus we propose two novel compositional plural semantics for CS's that are different from run-time choice. We study the basic properties of our plural semantics---compositionality, polarity, monotonicity for substitutions, and a restricted form of the bubbling proper...
Computing the Adler function from the vacuum polarization function
Horch, Hanno; Herdoíza, Gregorio; Jäger, Benjamin; Jüttner, Andreas; Wittig, Hartmut
2013-01-01
We use a lattice determination of the hadronic vacuum polarization tensor to study the associated Ward identities and compute the Adler function. The vacuum polarization tensor is computed from a combination of point-split and local vector currents, using two flavours of O($a$)-improved Wilson fermions. Partially twisted boundary conditions are employed to obtain a fine momentum resolution. The modifications of the Ward identities by lattice artifacts and by the use of twisted boundary conditions are monitored. We determine the Adler function from the derivative of the vacuum polarization function over a large region of momentum transfer $q^2$. As a first account of systematic effects, a continuum limit scaling analysis is performed in the large $q^2$ regime.
Building indifferentiable compression functions from the PGV compression functions
DEFF Research Database (Denmark)
Gauravaram, P.; Bagheri, Nasour; Knudsen, Lars Ramkilde
2016-01-01
Preneel, Govaerts and Vandewalle (PGV) analysed the security of single-block-length block cipher based compression functions assuming that the underlying block cipher has no weaknesses. They showed that 12 out of 64 possible compression functions are collision and (second) preimage resistant. Black......, Rogaway and Shrimpton formally proved this result in the ideal cipher model. However, in the indifferentiability security framework introduced by Maurer, Renner and Holenstein, all these 12 schemes are easily differentiable from a fixed input-length random oracle (FIL-RO) even when their underlying block...
[Functional cramps or functional dystonias in writers and musicians].
Chamagne, P
1986-01-01
The clinical evaluation in the "dystonies of function" or "impaired dexterity" reveals certain physical anomalies which either appear spontaneously or are triggered by specific tests: abnormal postures involving the trunck, head, and upper limb. During the professional gesture the physiological "pulley effect" on flexor tendons is accompanied with an interference effect produced by the displacement of the segments; this, adds up to an unbalance of the digital kinetic chain, building a locked functional system. The antagonist muscles begin to supply the deficiency of the agonist muscles. In addition, patients with a characteristic psychological ground suffer a more acute "disorganization" or a performing career.
GRID INFORMATION SECURITY FUNCTIONAL REQUIREMENT
Directory of Open Access Journals (Sweden)
Amy Poh Ai Ling
2011-07-01
Full Text Available This paper describes the background of smart information infrastructure and the needs for smart grid information security. It introduces the conceptual analysis to the methodology with the application ofhermeneutic circle and information security functional requirement identification. Information security for the grid market cover matters includes automation and communications industry that affects the operation of electric power systems and the functioning of the utilities that manage them and its awareness of this information infrastructure has become critical to the reliability of the power system. Community benefits from of cost savings, flexibility and deployment along with the establishment of wireless communications. However, concern revolves around the security protections for easily accessible devices such as the smart meter and the related communications hardware. On the other hand, the changing points between traditional versus smart grid networking trend and the information security importance on the communication field reflects the criticality of grid information security functional requirement identification. The goal of this paper is to identify the functional requirement and relate its significance addresses to the consumer requirement of an information security of a smart grid. Vulnerabilities may bring forth possibility for an attacker to penetrate a network, make headway admission to control software, alter it to load conditions that destabilize the grid in unpredictable ways. Focusing on the grid information security functional requirement is stepping ahead in developing consumer trust and satisfaction towardsmart grid completeness.
Consequences of CKD on Functioning.
Kittiskulnam, Piyawan; Sheshadri, Anoop; Johansen, Kirsten L
2016-07-01
Chronic kidney disease (CKD) is highly prevalent in the United States and throughout the world,(1) with approximately 13% of adults affected.(2) In addition, according to recent estimates, almost half of patients with CKD stages 3 to 5 are 70 years of age and older.(2) In the United States, the number of prevalent end-stage renal disease cases continues to increase in patients older than age 65. In light of the demographic characteristics of patients with CKD and ESRD, there has been considerable focus on associations between CKD and cardiovascular outcomes.(3) Until recently, less attention had been paid to other consequences of CKD in general and among older individuals with CKD in particular, but there is now solid evidence linking CKD with impairments of physical function, cognitive function, and emotional function and quality of life. This review summarizes available literature on these topics, focusing specifically on physical functioning and frailty, cognitive function, emotional health, including depression and anxiety, and health-related quality of life. PMID:27475661
Functionalized carbon nanotubes: biomedical applications
Directory of Open Access Journals (Sweden)
Vardharajula S
2012-10-01
Full Text Available Sandhya Vardharajula,1 Sk Z Ali,2 Pooja M Tiwari,1 Erdal Eroğlu,1 Komal Vig,1 Vida A Dennis,1 Shree R Singh11Center for NanoBiotechnology and Life Sciences Research, Alabama State University, Montgomery, AL, USA; 2Department of Microbiology, Osmania University, Hyderabad, IndiaAbstract: Carbon nanotubes (CNTs are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs limits their use in humans and many biological systems. The biocompatibility and low cytotoxicity of CNTs are attributed to size, dose, duration, testing systems, and surface functionalization. The functionalization of CNTs improves their solubility and biocompatibility and alters their cellular interaction pathways, resulting in much-reduced cytotoxic effects. Functionalized CNTs are promising novel materials for a variety of biomedical applications. These potential applications are particularly enhanced by their ability to penetrate biological membranes with relatively low cytotoxicity. This review is directed towards the overview of CNTs and their functionalization for biomedical applications with minimal cytotoxicity.Keywords: carbon nanotubes, cytotoxicity, functionalization, biomedical applications
Bernoulli numbers and zeta functions
Arakawa, Tsuneo; Kaneko, Masanobu
2014-01-01
Two major subjects are treated in this book. The main one is the theory of Bernoulli numbers and the other is the theory of zeta functions. Historically, Bernoulli numbers were introduced to give formulas for the sums of powers of consecutive integers. The real reason that they are indispensable for number theory, however, lies in the fact that special values of the Riemann zeta function can be written by using Bernoulli numbers. This leads to more advanced topics, a number of which are treated in this book: Historical remarks on Bernoulli numbers and the formula for the sum of powers of consecutive integers; a formula for Bernoulli numbers by Stirling numbers; the Clausen–von Staudt theorem on the denominators of Bernoulli numbers; Kummer's congruence between Bernoulli numbers and a related theory of p-adic measures; the Euler–Maclaurin summation formula; the functional equation of the Riemann zeta function and the Dirichlet L functions, and their special values at suitable integers; various formulas of ...
Factor XIII: Structure and Function.
Schroeder, Verena; Kohler, Hans P
2016-06-01
Over the last two decades, it became evident that factor XIII (FXIII) is not only a crucial determinant of clot characteristics but also has potentially important functions in many various fields such as bone biology, immunity, and adipogenesis. In this review, we aim to summarize the latest findings regarding structure and function of FXIII. In regard to FXIII structure, much progress has been made recently to understand how its subunits are held together. In the A subunit, the activation peptide has a crucial role in the formation of FXIII-A2 dimers. In the B subunit, Sushi domains that are involved in binding to the A subunit and in B2 dimer formation have been identified. In regard to FXIII function, interactions with immune cells and the complement system have been described. A novel function of FXIII-A in adipogenesis has been suggested. The role of FXIII-A in osteoblast differentiation has been further investigated; however, a novel double knockout mouse deficient in both FXIII-A and transglutaminase 2 showed normal bone formation. Thus, more research, in particular, into the cellular functions of FXIII-A is still required. PMID:27019464
Detecting aquaporin function and regulation
Madeira, Ana; Moura, Teresa; Soveral, Graça
2016-02-01
Water is the major component of cells and tissues throughout all forms of life. Fluxes of water and solutes through cell membranes and epithelia are essential for osmoregulation and energy homeostasis. Aquaporins are membrane channels expressed in almost every organism and involved in the bidirectional transfer of water and small solutes across cell membranes. Aquaporins have important biological roles and have been implicated in several pathophysiological conditions suggesting a great translational potential in aquaporin-based diagnostic and therapeutics. Detecting aquaporin function is critical for assessing regulation and screening for new activity modulators that can prompt the development of efficient medicines. Appropriate methods for functional analysis comprising suitable cell models and techniques to accurately evaluate water and solute membrane permeability are essential to validate aquaporin function and assess short-term regulation. The present review describes established assays commonly used to assess aquaporin function in cells and tissues, as well as the experimental biophysical strategies required to reveal functional regulation and identify modulators, the first step for aquaporin drug discovery.
``Backpack'' Functionalized Living Immune Cells
Swiston, Albert; Um, Soong Ho; Irvine, Darrell; Cohen, Robert; Rubner, Michael
2009-03-01
We demonstrate that functional polymeric ``backpacks'' built from polyelectrolyte multilayers (PEMs) can be attached to a fraction of the surface area of living, individual lymphocytes. Backpacks containing fluorescent polymers, superparamagnetic nanoparticles, and commercially available quantum dots have been attached to B and T-cells, which may be spatially manipulated using a magnetic field. Since the backpack does not occlude the entire cellular surface from the environment, this technique allows functional synthetic payloads to be attached to a cell that is free to perform its native functions, thereby synergistically utilizing both biological and synthetic functionalities. For instance, we have shown that backpack-modified T-cells are able to migrate on surfaces for several hours following backpack attachment. Possible payloads within the PEM backpack include drugs, vaccine antigens, thermally responsive polymers, nanoparticles, and imaging agents. We will discuss how this approach has broad potential for applications in bioimaging, single-cell functionalization, immune system and tissue engineering, and cell-based therapeutics where cell-environment interactions are critical.
Functional food science and behaviour and psychological functions.
Bellisle, F; Blundell, J E; Dye, L; Fantino, M; Fern, E; Fletcher, R J; Lambert, J; Roberfroid, M; Specter, S; Westenhöfer, J; Westerterp-Plantenga, M S
1998-08-01
The impact of ingesting various foods on psychological and behavioural functions is a topic of both interest and concern to the general public. In this article, the scientific literature concerning demonstrated cause-and-effect relationships is reviewed, beginning with methodological considerations specific to the quantification of particular behaviours and psychological events. The essential function of food is to satisfy hunger and the need for essential nutrients. The contributions of macronutrients to appetite and satiety are described, as well as their impact on metabolism and energy balance. Functional properties of macronutrient substitutes (high-intensity sweeteners, fat replacers) and flavour enhancers are examined in relation to their contribution to hunger, satiety, and energy balance. The effects of foods and individual nutrients on the performance of diverse psychomotor tasks are studied with consideration given to the various validated quantitative tools used to assess behaviour. The effects of food components on activation, sedation, and affective states such as dysphoria are also reviewed, with special attention given to brain function and neuroactive substances such as serotonin and the endorphins. The case of hyperactivity in children is given special emphasis with reference to the potential influence of sugar and food additives. Safety issues related to food constituents and additives are discussed. Finally, a set of criteria is proposed for the evaluation and elaboration of studies in the behavioural and psychological fields, along with suggestions for future research.
Functional tasks exercise improves daily function in older women
Vreede, P.L. de
2006-01-01
Ageing is characterised by a reduction in physical reserve, the physiological capacity in excess of that needed for daily activities, that provides a margin of safety that absorbs age- or disease-related changes without a loss in function. When physical capacity falls below the ability required for
ON STEIN-WEISS CONJUGATEHARMONIC FUNCTION ANDOCTONION ANALYTIC FUNCTION
Institute of Scientific and Technical Information of China (English)
Li Xingmin; Peng Lizhong
2000-01-01
It is shown that the Stein-Weiss conjugate harmonic funciton is the Quarternion and the Octonion analytic function. We find a counter example to show the converse is not ture in the Octonion case, by which we have answered the question proposed in [1].
High throughout reproducible cantilever functionalization
Evans, Barbara R; Lee, Ida
2014-11-25
A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.
High throughput reproducible cantilever functionalization
Evans, Barbara R; Lee, Ida
2014-01-21
A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.
Orthogonal Polynomials and Special Functions
Assche, Walter
2003-01-01
The set of lectures from the Summer School held in Leuven in 2002 provide an up-to-date account of recent developments in orthogonal polynomials and special functions, in particular for algorithms for computer algebra packages, 3nj-symbols in representation theory of Lie groups, enumeration, multivariable special functions and Dunkl operators, asymptotics via the Riemann-Hilbert method, exponential asymptotics and the Stokes phenomenon. The volume aims at graduate students and post-docs working in the field of orthogonal polynomials and special functions, and in related fields interacting with orthogonal polynomials, such as combinatorics, computer algebra, asymptotics, representation theory, harmonic analysis, differential equations, physics. The lectures are self-contained requiring only a basic knowledge of analysis and algebra, and each includes many exercises.
SCATTERING FUNCTION OF POLYMER BLENDS
Institute of Scientific and Technical Information of China (English)
Lin-ping Ke; Mei-li Guo; De-lu Zhao
2004-01-01
For a system of flexible polymer molecules, the concepts of two concentrations, namely the segmental and the molecular concentrations, have been proposed in this paper. The former is equivalent to the volume fraction. The latter can be defined as the number of the gravity centers of macromolecules in a unit volume. The two concentrations should be correlated with each other by the conformational function of the polymer chain and should be discussed in different thermodynamic equations. On the basis of these concepts it has been proved that the Flory-Huggins entropy of mixing should be the result of the mixing "ideal gases of the gravity centers of macromolecules". The general correlation between the free energy of mixing and the scattering function (structural factor) of polymer blends has been studied based on the general fluctuation theory. When the Flory-Huggins free energy of mixing is adopted, the de Gennes scattering function of a polymer blend can be derived.
Breast cancer and sexual function.
Boswell, Erica N; Dizon, Don S
2015-04-01
As the most common malignancy affecting women within the United States, breast cancer can bring about multiple physical and psychological challenges. Among the greatest challenges are those associated with female sexual function. Chemotherapy, endocrine therapy, surgeries and radiation can all have a large effect in altering a woman's sexual health and function. Sexual concerns result in significant emotional distress, including sadness/depression, issues related to personal appearance, stigma, and negative impacts on personal relationships. In this article, we discuss some of the specific challenges that present with each type of treatment and the socio-physical impact they have on survivorship. Among the most detrimental to sexual function, are the use of chemotherapy and endocrine therapy. Additionally, anatomical changes that transpire in patients who have undergone surgery or radiation therapy (RT), disrupt perceptions of body image. Here we will discuss and also review the contemporary literature to determine effective management and treatment of sexual dysfunction. PMID:26816822
Iacovacci, Jacopo; Arenas, Alex; Bianconi, Ginestra
2016-01-01
Recently it has been recognized that many complex social, technological and biological networks have a multilayer nature and can be described by multiplex networks. Multiplex networks are formed by a set of nodes connected by links having different connotations forming the different layers of the multiplex. Characterizing the centrality of the nodes in a multiplex network is a challenging task since the centrality of the node naturally depends on the importance associated to links of a certain type. Here we propose to assign to each node of a multiplex network a centrality called Functional Multiplex PageRank that is a function of the weights given to every different pattern of connections (multilinks) existent in the multiplex network between any two nodes. Since multilinks distinguish all the possible ways in which the links in different layers can overlap, the Functional Multiplex PageRank can describe important non-linear effects when large relevance or small relevance is assigned to multilinks with overl...
Web platform for functional design
Dijmarescu, M. R.; Dijmarescu, M. C.
2015-11-01
Today's global competitive trends, especially those related to industries, determine a much higher degree of pressure and demands for substantial innovation driven improvements, flexible and time sensitive solutions. Improving and optimizing the design activity by shortening its timeline and maintaining a high quality level for its output have become the main success factors. The evolution of design activity is strongly related to the evolution of education and research made in the design field. Thus, the development of web tools which can contain knowledge about mechanical products functionality and structure may be an important achievement for the education and industry. This paper presents a web platform which contains functional-constructive knowledge in the area of mechanical design field and was developed to support design activity. The proposed web tool can provide any user, even one without background in design theory, information about the functionality of products and the way it is related to the product structure.
Distributed anonymous discrete function computation
Hendrickx, Julien M; Tsitsiklis, John N
2010-01-01
We propose a model for deterministic distributed function computation by a network of identical and anonymous nodes. In this model, each node has bounded computation and storage capabilities that do not grow with the network size. Furthermore, each node only knows its neighbors, not the entire graph. Our goal is to characterize the class of functions that can be computed within this model. In our main result, we provide a necessary condition for computability which we show to be nearly sufficient, in the sense that every function that violates this condition can at least be approximated. The problem of computing suitably rounded averages in a distributed manner plays a central role in our development; we provide an algorithm that solves it in time that grows quadratically with the size of the network.
Functional foods: an ecologic perspective.
Marriott, B M
2000-06-01
A functional food is defined as any food or food ingredient that may provide a health benefit beyond that conferred by the nutrients the food contains. As nutrition scientists move into this arena, they must build on the wealth of information that already exists in plant biology. In particular, the evolutionary and physiologic bases for the production of secondary plant chemicals in plants must be considered in order to plan meaningful experiments for testing the functionality of these chemical compounds for humans. One problem that may arise is that in using the term functional food, the meaning may be lost in the continued proliferation of related terms used in product marketing. The new National Institutes of Health Office of Dietary Supplements addressed some of these issues as it developed the operating definitions described in this report.
Estimating Functions and Semiparametric Models
DEFF Research Database (Denmark)
Labouriau, Rodrigo
1996-01-01
of the attainability of the bounds for the concentration of regular asymptotic linear estimating sequences by estimators derived from estimating functions. The main class of models considered in the second part of the thesis (chapter 5) are constructed by assuming that the expectation of a number of given square...... is developed in details in a context of semiparametric models. There does not to the knowledge of the author, exist any such systematic treatment of estimating functions for semiparametric models in the literature. The second part studies some classes of semiparametric models described below. The material...... contained in this part of the thesis constitutes an original contribution. There can be found the detailed characterization of the class of regular estimating functions, a calculation of efficient regular asymptotic linear estimating sequences (\\ie the classical optimality theory) and a discussion...
Generating functions for Hecke operators
Shehadeh, Hala Hajj; Jaafar, Samar; Khuri-Makdisi, Kamal
2006-01-01
Fix a prime N, and consider the action of the Hecke operator T_N on the space M_k(SL(2,Z)) of modular forms of full level and varying weight k. The coefficients of the matrix of T_N with respect to the basis {E_4^i E_6^j | 4i + 6j = k} for M_k(SL(2,Z)) can be combined for varying k into a generating function F_N. We show that this generating function is a rational function for all N, and present a systematic method for computing F_N. We carry out the computations for N = 2, 3, 5, and indicate...