Zebrafish arl6ip1 is required for neural crest development during embryogenesis.
Directory of Open Access Journals (Sweden)
Chi-Tang Tu
Full Text Available BACKGROUND: Although the embryonic expression pattern of ADP ribosylation factor-like 6 interacting protein 1 (Arl6ip1 has been reported, its function in neural crest development is unclear. METHODS/PRINCIPAL FINDINGS: We found that knockdown of Arl6ip1 caused defective embryonic neural crest derivatives that were particularly severe in craniofacial cartilages. Expressions of the ectodermal patterning factors msxb, dlx3b, and pax3 were normal, but the expressions of the neural crest specifier genes foxd3, snai1b, and sox10 were greatly reduced. These findings suggest that arl6ip1 is essential for specification of neural crest derivatives, but not neural crest induction. Furthermore, we revealed that the streams of crestin- and sox10-expressing neural crest cells, which migrate ventrally from neural tube into trunk, were disrupted in arl6ip1 morphants. This migration defect was not only in the trunk neural crest, but also in the enteric tract where the vagal-derived neural crest cells failed to populate the enteric nervous system. We found that this migration defect was induced by dampened Shh signaling, which may have resulted from defective cilia. These data further suggested that arl6ip1 is required for neural crest migration. Finally, by double-staining of TUNEL and crestin, we confirmed that the loss of neural crest cells could not be attributed to apoptosis. CONCLUSIONS/SIGNIFICANCE: Therefore, we concluded that arl6ip1 is required for neural crest migration and sublineage specification.
Genetic and bibliographic information: ARL6 [GenLibi
Lifescience Database Archive (English)
Full Text Available ARL6 ADP-ribosylation factor-like 6 human Bardet-Biedl Syndrome (MeSH) Nervous Syst...Diseases (C10.228.140.617) > Bardet-Biedl Syndrome (C10.228.140.617.200) Congenital, Hereditary, and Neonata...lities, Multiple (C16.131.077) > Bardet-Biedl Syndrome (C16.131.077.112) 99A0284114 ...
Institute of Scientific and Technical Information of China (English)
沈秋红; 汤颖; 乐砷; 程雁
2014-01-01
目的:研究小GTP酶Arl6对sonic hedgehog(Shh)信号通路的调控作用.方法:构建Arl6敲低稳转细胞株,检测Shh通路靶基因Glil及Ptch1的mRNA表达水平;激光共聚焦显微镜下观察Arl6在原纤毛的定位,并且检测Arl6敲低细胞中原纤毛的生成情况.结果:Arl6的敲低抑制Shh信号通路的完全激活,在高浓度Shh条件性培养基或Smo激动剂Purm刺激下,靶基因Gli1 mRNA表达水平明显低于对照shControl组(P＜0.01),Ptch1 mRNA的表达水平也明显降低(P＜ 0.05);Arl6定位于原纤毛的基部小体,Arl6的缺失会影响原纤毛的生成;同时,Shh信号会刺激Arl6的表达(P＜0.05).结论:小GTP酶Arl6的敲低抑制Shh通路的完全活化,与其抑制原纤毛生成有关.
Directory of Open Access Journals (Sweden)
Fedoua Gandia
2014-07-01
Full Text Available The study was carried out to investigate the effects of inhaled Mg alone and associated with F in the treatment of bronchial hyperresponsiveness. 43 male Wistar rats were randomly divided into four groups and exposed to inhaled NaCl 0.9%, MeCh, MgSO4 and MgF2. Pulmonary changes were assessed by means of functional tests and quantitative histological examination of lungs and trachea. Results revealed that delivery of inhaled Mg associated with F led to a significant decrease of total lung resistance better than inhaled Mg alone (p < 0.05. Histological examinations illustrated that inhaled Mg associated with F markedly suppressed muscular hypertrophy (p = 0.034 and bronchoconstriction (p = 0.006 in MeCh treated rats better than inhaled Mg alone. No histological changes were found in the trachea. This study showed that inhaled Mg associated with F attenuated the main principle of the central components of changes in MeCh provoked experimental asthma better than inhaled Mg alone, potentially providing a new therapeutic approach against asthma.
Sun, Ying
2011-01-01
This article proposes an informative exploratory tool, the functional boxplot, for visualizing functional data, as well as its generalization, the enhanced functional boxplot. Based on the center outward ordering induced by band depth for functional data, the descriptive statistics of a functional boxplot are: the envelope of the 50% central region, the median curve, and the maximum non-outlying envelope. In addition, outliers can be detected in a functional boxplot by the 1.5 times the 50% central region empirical rule, analogous to the rule for classical boxplots. The construction of a functional boxplot is illustrated on a series of sea surface temperatures related to the El Niño phenomenon and its outlier detection performance is explored by simulations. As applications, the functional boxplot and enhanced functional boxplot are demonstrated on children growth data and spatio-temporal U.S. precipitation data for nine climatic regions, respectively. This article has supplementary material online. © 2011 American Statistical Association.
DEFF Research Database (Denmark)
Vargas-Zúñiga, Gabriela; Sessler, Jonathan; Bähring, Steffen
2016-01-01
as the extraction and transport of anionic species and ion pairs including cesium halide and sulfate salts. It is divided into seven sections. The first section describes the synthetic methods employed to functionalized calix[4]pyrrole. The second section focuses on functionalized calix[4]pyrroles that display...... enhanced anion binding properties compared to the non-functionalized parent system, octamethylcalix[4]pyrrole. The use of functionalized calix[4]pyrroles containing a fluorescent group or functionalized calix[4]pyrroles as building blocks for the preparation of stimulus-responsive materials is discussed...... and the eventual development of therapeutics that function via the transport of anions across cell membranes, are discussed....
Markushevich, A I
1966-01-01
Entire Functions focuses on complex numbers and the algebraic operations on them and the basic principles of mathematical analysis.The book first elaborates on the concept of an entire function, including the natural generalization of the concept of a polynomial and power series. The text then takes a look at the maximum absolute value and the order of an entire function, as well as calculations for the coefficients of power series representing a given function, use of integrals, and complex numbers. The publication elaborates on the zeros of an entire function and the fundamen
DEFF Research Database (Denmark)
Della Pia, Eduardo Antonio; Hansen, Randi Westh; Zoonens, Manuela
2014-01-01
Amphipols are amphipathic polymers that stabilize membrane proteins isolated from their native membrane. They have been functionalized with various chemical groups in the past years for protein labeling and protein immobilization. This large toolbox of functionalized amphipols combined with their......Amphipols are amphipathic polymers that stabilize membrane proteins isolated from their native membrane. They have been functionalized with various chemical groups in the past years for protein labeling and protein immobilization. This large toolbox of functionalized amphipols combined...... surfaces for various applications in synthetic biology. This review summarizes the properties of functionalized amphipols suitable for synthetic biology approaches....
DEFF Research Database (Denmark)
Campi, Stefano; Gardner, Richard; Gronchi, Paolo;
2012-01-01
Variants of the brightness function of a convex body K in n-dimensional Euclidean are investigated. The Lambertian lightness function L(K; v , w ) gives the total reflected light resulting from illumination by a light source at infinity in the direction w that is visible when looking...... in the direction v . The partial brightness function R( K ; v , w ) gives the area of the projection orthogonal to v of the portion of the surface of K that is both illuminated by a light source from the direction w and visible when looking in the direction v . A class of functions called lightness functions...... is introduced that includes L(K;.) and R(K;.) as special cases. Much of the theory of the brightness function like uniqueness, stability, and the existence and properties of convex bodies of maximal and minimal volume with finitely many function values equal to those of a given convex body, is extended...
Institute of Scientific and Technical Information of China (English)
王雷
2008-01-01
<正>A power function of degree n is a function of the form f(x)=ax~n.For large n,it appears that the graph coincide with the x-axis near the origin,but it does not;the graph actually touches the x—axis only at the origin.
Burns, Daniel; Wang, Zuoqin
2008-01-01
In this article we discuss the role of stability functions in geometric invariant theory and apply stability function techniques to problems in toric geometry. In particular we show how one can use these techniques to recover results of Burns-Guillemin-Uribe and Shiffman-Tate-Zelditch on asymptotic properties of sections of holomorphic line bundles over toric varieties.
CARDINAL FUNCTIONS AND INTEGRAL FUNCTIONS
MIRCEA E. ŞELARIU; FLORENTIN SMARANDACHE; MARIAN NIŢU
2015-01-01
This paper presents the correspondences of the eccentric mathematics of cardinal and integral functions and centric mathematics, or ordinary mathematics. Centric functions will also be presented in the introductory section, because they are, although widely used in undulatory physics, little known.
DEFF Research Database (Denmark)
Danvy, Olivier
1998-01-01
A string-formatting function such as printf in C seemingly requires dependent types, because its control string determines the rest of its arguments. We show how changing the representation of the control string makes it possible to program printf in ML (which does not allow dependent types......). The result is well typed and perceptibly more efficient than the corresponding library functions in Standard ML of New Jersey and in Caml....
DEFF Research Database (Denmark)
Danvy, Olivier
2000-01-01
A string-formatting function such as printf in C seemingly requires dependent types, because its control string determines the rest of its arguments. Examples: formula here We show how changing the representation of the control string makes it possible to program printf in ML (which does not allow...... dependent types). The result is well typed and perceptibly more efficient than the corresponding library functions in Standard ML of New Jersey and in Caml....
Directory of Open Access Journals (Sweden)
J. A. Chatfield
1978-01-01
Full Text Available Suppose N is a Banach space of norm |•| and R is the set of real numbers. All integrals used are of the subdivision-refinement type. The main theorem [Theorem 3] gives a representation of TH where H is a function from R×R to N such that H(p+,p+, H(p,p+, H(p−,p−, and H(p−,p each exist for each p and T is a bounded linear operator on the space of all such functions H. In particular we show that TH=(I∫abfHdα+∑i=1∞[H(xi−1,xi−1+−H(xi−1+,xi−1+]β(xi−1+∑i=1∞[H(xi−,xi−H(xi−,xi−]Θ(xi−1,xiwhere each of α, β, and Θ depend only on T, α is of bounded variation, β and Θ are 0 except at a countable number of points, fH is a function from R to N depending on H and {xi}i=1∞ denotes the points P in [a,b]. for which [H(p,p+−H(p+,p+]≠0 or [H(p−,p−H(p−,p−]≠0. We also define an interior interval function integral and give a relationship between it and the standard interval function integral.
Nambudiripad, K B M
2014-01-01
After presenting the theory in engineers' language without the unfriendly abstraction of pure mathematics, several illustrative examples are discussed in great detail to see how the various functions of the Bessel family enter into the solution of technically important problems. Axisymmetric vibrations of a circular membrane, oscillations of a uniform chain, heat transfer in circular fins, buckling of columns of varying cross-section, vibrations of a circular plate and current density in a conductor of circular cross-section are considered. The problems are formulated purely from physical considerations (using, for example, Newton's law of motion, Fourier's law of heat conduction electromagnetic field equations, etc.) Infinite series expansions, recurrence relations, manipulation of expressions involving Bessel functions, orthogonality and expansion in Fourier-Bessel series are also covered in some detail. Some important topics such as asymptotic expansions, generating function and Sturm-Lioville theory are r...
Institute of Scientific and Technical Information of China (English)
王雷
2008-01-01
<正>Polynomial functions are among the sim- plest expressions in algebra.They are easy to evaluate:only addition and repeated multipli- cation are required.Because of this,they are often used to approximate other more compli-
Kleibeuker, JH; Thijs, JC
2004-01-01
Purpose of review Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic me
Institute of Scientific and Technical Information of China (English)
K.H.DTZ
2007-01-01
1 Results The lecture will address aspects of functional organometallics related to the development of novel organometallic materials.In chromium complexes of fused arenes-regio-and diastereoselectively accessible by chromium-templated benzannulation of arylcarbenes by alkynes[1]-a haptotropic migration of the chromium fragment along the π-face of fused arenes is controlled by both thermodynamics and the substitution pattern of the arene and the metal coligand sphere,and can be applied towards an organo...
Institute of Scientific and Technical Information of China (English)
2005-01-01
2005200 The effect of body position changes on lung function, lung CT imaging and pathology in an oleic acid induced acute lung injury model. JI Xin-ping (戢新平), et al. Dept Emergency, 1st Affili Hosp, China Med Univ, Shenyang 110001. Chin J Tuberc Respir Dis, 2005;28(1) :33-36. Objective: To study the effect of body position changes on lung mechanics, oxygenation, CT images and pathology in an oleic acid-induced acute lung injury (ALl) model. Methods: The study groups con-
Asadchy, V S; Vehmas, J; Tretyakov, S A
2014-01-01
Conventional mirrors obey Snell's reflection law: a plane wave is reflected as a plane wave, at the same angle. To engineer spatial distributions of fields reflected from a mirror, one can either shape the reflector (for example, creating a parabolic reflector) or position some phase-correcting elements on top of a mirror surface (for example, designing a reflectarray antenna). Here we show, both theoretically and experimentally, that full-power reflection with general control over reflected wave phase is possible with a single-layer array of deeply sub-wavelength inclusions. These proposed artificial surfaces, metamirrors, provide various functions of shaped or nonuniform reflectors without utilizing any mirror. This can be achieved only if the forward and backward scattering of the inclusions in the array can be engineered independently, and we prove that it is possible using electrically and magnetically polarizable inclusions. The proposed sub-wavelength inclusions possess desired reflecting properties at...
Functions of bounded variation
Lind, Martin
2006-01-01
The paper begins with a short survey of monotone functions. The functions of bounded variation are introduced and some basic properties of these functions are given. Finally the jump function of a function of bounded variation is defined.
Relations between Lipschitz functions and convex functions
Institute of Scientific and Technical Information of China (English)
RUAN Yingbin
2005-01-01
We discuss the relationship between Lipschitz functions and convex functions.By these relations, we give a sufficient condition for the set of points where Lipschitz functions on a Hilbert space is Frechet differentiable to be residual.
Gaussian Functions, Γ-Functions and Wavelets
Institute of Scientific and Technical Information of China (English)
蔡涛; 许天周
2003-01-01
The relations between Gaussian function and Γ-function is revealed first at one-dimensional situation. Then, the Fourier transformation of n-dimensional Gaussian function is deduced by a lemma. Following the train of thought in one-dimensional situation, the relation between n-dimensional Gaussian function and Γ-function is given. By these, the possibility of arbitrary derivative of an n-dimensional Gaussian function being a mother wavelet is indicated. The result will take some enlightening role in exploring the internal relations between Gaussian function and Γ-function as well as in finding high-dimensional mother wavelets.
On quasinearly subharmonic functions
Dovgoshey, O.; Riihentaus, J.
2016-01-01
We recall the definition of quasinearly subharmonic functions, point out that this function class includes, among others, subharmonic functions, quasisubharmonic functions, nearly subharmonic functions and essentially almost subharmonic functions. It is shown that the sum of two quasinearly subharmonic functions may not be quasinearly subharmonic. Moreover, we characterize the harmonicity via quasinearly subharmonicity.
Bayesian function-on-function regression for multilevel functional data.
Meyer, Mark J; Coull, Brent A; Versace, Francesco; Cinciripini, Paul; Morris, Jeffrey S
2015-09-01
Medical and public health research increasingly involves the collection of complex and high dimensional data. In particular, functional data-where the unit of observation is a curve or set of curves that are finely sampled over a grid-is frequently obtained. Moreover, researchers often sample multiple curves per person resulting in repeated functional measures. A common question is how to analyze the relationship between two functional variables. We propose a general function-on-function regression model for repeatedly sampled functional data on a fine grid, presenting a simple model as well as a more extensive mixed model framework, and introducing various functional Bayesian inferential procedures that account for multiple testing. We examine these models via simulation and a data analysis with data from a study that used event-related potentials to examine how the brain processes various types of images.
Modelling distribution functions and fragmentation functions
Rodrigues, J; Mulders, P J
1995-01-01
We present examples for the calculation of the distribution and fragmentation functions using the representation in terms of non-local matrix elements of quark field operators. As specific examples, we use a simple spectator model to estimate the leading twist quark distribution functions and the fragmentation functions for a quark into a nucleon or a pion.
Institute of Scientific and Technical Information of China (English)
华建文; 刘立人; 王宁
1997-01-01
A recipe to construct the exact dual self-Fourier-Fresnel-transform functions is shown, where the Dirac comb function and transformable even periodic function are used. The mathematical proof and examples are given Then this kind of self-transform function is extended to the feasible optical dual self-transform functions.
Kargın, Levent; Kurt, Veli
2015-01-01
In this study, obtaining the matrix analog of the Euler's reflection formula for the classical gamma function we expand the domain of the gamma matrix function and give a infinite product expansion of sinπxP. Furthermore we define Riemann zeta matrix function and evaluate some other matrix integrals. We prove a functional equation for Riemann zeta matrix function.
Functionality and homogeneity.
2011-01-01
Functionality and homogeneity are two of the five Sustainable Safety principles. The functionality principle aims for roads to have but one exclusive function and distinguishes between traffic function (flow) and access function (residence). The homogeneity principle aims at differences in mass, spe
Properties of Bourbaki's Function
McCollum, James
2010-01-01
We examine Bourbaki's function, an easily-constructed continuous but nowhere-differentiable function, and explore properties including functional identities, the antiderivative, and the Hausdorff dimension of the graph.
... be limited. Home Visit Global Sites Search Help? Platelet Function Tests Share this page: Was this page helpful? ... their patients by ordering one or more platelet function tests. Platelet function testing may include one or more of ...
Congenital platelet function defects
... storage pool disorder; Glanzmann's thrombasthenia; Bernard-Soulier syndrome; Platelet function defects - congenital ... Congenital platelet function defects are bleeding disorders that ... function, even though there are normal platelet numbers. Most ...
Random functions and turbulence
Panchev, S
1971-01-01
International Series of Monographs in Natural Philosophy, Volume 32: Random Functions and Turbulence focuses on the use of random functions as mathematical methods. The manuscript first offers information on the elements of the theory of random functions. Topics include determination of statistical moments by characteristic functions; functional transformations of random variables; multidimensional random variables with spherical symmetry; and random variables and distribution functions. The book then discusses random processes and random fields, including stationarity and ergodicity of random
Functional Maximum Autocorrelation Factors
DEFF Research Database (Denmark)
Larsen, Rasmus; Nielsen, Allan Aasbjerg
2005-01-01
Purpose. We aim at data where samples of an underlying function are observed in a spatial or temporal layout. Examples of underlying functions are reflectance spectra and biological shapes. We apply functional models based on smoothing splines and generalize the functional PCA in\\verb+~+\\$\\backsl......Purpose. We aim at data where samples of an underlying function are observed in a spatial or temporal layout. Examples of underlying functions are reflectance spectra and biological shapes. We apply functional models based on smoothing splines and generalize the functional PCA in...
Acquired platelet function defect
Acquired qualitative platelet disorders; Acquired disorders of platelet function ... blood clotting. Disorders that can cause problems in platelet function include: Idiopathic thrombocytopenic purpura Chronic myelogenous leukemia Multiple ...
Functional microorganisms for functional food quality.
Gobbetti, M; Cagno, R Di; De Angelis, M
2010-09-01
Functional microorganisms and health benefits represent a binomial with great potential for fermented functional foods. The health benefits of fermented functional foods are expressed either directly through the interactions of ingested live microorganisms with the host (probiotic effect) or indirectly as the result of the ingestion of microbial metabolites synthesized during fermentation (biogenic effect). Since the importance of high viability for probiotic effect, two major options are currently pursued for improving it--to enhance bacterial stress response and to use alternative products for incorporating probiotics (e.g., ice cream, cheeses, cereals, fruit juices, vegetables, and soy beans). Further, it seems that quorum sensing signal molecules released by probiotics may interact with human epithelial cells from intestine thus modulating several physiological functions. Under optimal processing conditions, functional microorganisms contribute to food functionality through their enzyme portfolio and the release of metabolites. Overproduction of free amino acids and vitamins are two classical examples. Besides, bioactive compounds (e.g., peptides, γ-amino butyric acid, and conjugated linoleic acid) may be released during food processing above the physiological threshold and they may exert various in vivo health benefits. Functional microorganisms are even more used in novel strategies for decreasing phenomenon of food intolerance (e.g., gluten intolerance) and allergy. By a critical approach, this review will aim at showing the potential of functional microorganisms for the quality of functional foods.
Rough function model and rough membership function
Institute of Scientific and Technical Information of China (English)
Wang Yun; Guan Yanyong; Huang Zhiqin
2008-01-01
Two pairs of approximation operators, which are the scale lower and upper approximations as well as the real line lower and upper approximations, are defined. Their properties and antithesis characteristics are analyzed. The rough function model is generalized based on rough set theory, and the scheme of rough function theory is made more distinct and complete. Therefore, the transformation of the real function analysis from real line to scale is achieved. A series of basic concepts in rough function model including rough numbers, rough intervals, and rough membership functions are defined in the new scheme of the rough function model. Operating properties of rough intervals similar to rough sets are obtained. The relationship of rough inclusion and rough equality of rough intervals is defined by two kinds of tools, known as the lower (upper) approximation operator in real numbers domain and rough membership functions. Their relative properties are analyzed and proved strictly, which provides necessary theoretical foundation and technical support for the further discussion of properties and practical application of the rough function model.
Entire functions sharing one small function
Institute of Scientific and Technical Information of China (English)
LI Yun-tong; CAO Yao
2007-01-01
The uniqueness problem of entire functions sharing one small function was studied. By Picard's Theorem, we proved that for two transcendental entire functions f (z) and g(z), a positive integer n≥9, and a(z) (not identically eaqual to zero) being a common small function related to f (z) and g(z), if f n(z)(f(z)-1)f'(z) and gn(z)(g'z)-1)g'(z) share a(z) CM, where CM is counting multiplicity, then g(z)≡f (z). This is an extended version of Fang and Hong's theorem [ Fang ML, Hong W, A unicity theorem for entire functions concerning differential polynomials, Journal of Indian Pure Applied Mathematics, 2001, 32 (9): 1343-1348].
Hepatic (Liver) Function Panel
... 1- to 2-Year-Old Blood Test: Hepatic (Liver) Function Panel KidsHealth > For Parents > Blood Test: Hepatic (Liver) Function Panel Print A A A What's in ... Is The hepatic function panel, also known as liver function tests, is a group of seven tests ...
Institute of Scientific and Technical Information of China (English)
丁夏畦; 罗佩珠
2004-01-01
In this paper the authors introduce some new ideas on generalized numbers and generalized weak functions. They prove that the product of any two weak functions is a generalized weak function. So in particular they solve the problem of the multiplication of two generalized functions.
DEFF Research Database (Denmark)
Bysted, Tommy Kristensen; Hamila, R.; Gabbouj, M.;
1998-01-01
A new correlation function called the Teager correlation function is introduced in this paper. The connection between this function, the Teager energy operator and the conventional correlation function is established. Two applications are presented. The first is the minimization of the Teager err...... norm and the second one is the use of the instantaneous Teager correlation function for simultaneous estimation of TDOA and FDOA (Time and Frequency Difference of Arrivals)....
Relations between Lipschitz functions and convex functions
Institute of Scientific and Technical Information of China (English)
无
2005-01-01
[1]Zajicek, J., On the differentation of convex functions in finite and infinite dimensional spaces, Czech J. Math.,1979, 29: 340-348.[2]Hu, T. C., Klee, V. L., Larman, D. G., Optimization of globally convex functions, SIAM J. Control Optim., 1989,27: 1026-1047.[3]Cepedello Boiso, M., Approximation of Lipschitz functions by △-convex functions in Banach spaces, Israel J.Math., 1998, 106: 269-284.[4]Asplund, E., Frechet differentiability of convex functions, Acta Math., 1968, 121: 31-47.[5]Johnson, J. A., Lipschitz spaces, Pacific J. Math, 1974, 51: 177-186.[6]Stromberg, T., The operation of infimal convolution, Dissert. Math., (Rozprawy Mat.), 1996, 325: 58.[7]Kadison, R. V., Ringrose, J. R., Fundamentals of the theory of operator algebras, volume Ⅰ: Elementary Theory,Graduate Studies in Math., vol. 15, Amer. Math. Soc., 1997.[8]Phelps, R. R., Convex functions,monotone operators and differentiability, Lect. Notes in Math., vol. 1364,Springer-Verlag, 1977.[9]Lindenstrauss, J., On operators which attain their norm, Israel J. Math., 1963, 1: 139-148.[10]Press, D., Gateaux differentiable functions are somewhere Frechet differentiable, Rend. Circ. Mat. Palermo,1984, 33: 122-133.[11]Press, D., Differentiability of Lipschitz functions on Banach spaces, J. Funct. Anal., 1990, 91:312-345.[12]Lindenstrauss, J., Press, D., On Frechet differentiability of Lipschitz maps between Banach spaces, Annals of Math., 2003, 157: 257-288.[13]Press, D., Gateaux differentiable Lipschitz functions need not be Frechet differentiable on a residual set, Supplemento Rend. Circ. Mat. Palermo, Serie Ⅱ, 1982, 2: 217-222.
Sampling functions for geophysics
Giacaglia, G. E. O.; Lunquist, C. A.
1972-01-01
A set of spherical sampling functions is defined such that they are related to spherical-harmonic functions in the same way that the sampling functions of information theory are related to sine and cosine functions. An orderly distribution of (N + 1) squared sampling points on a sphere is given, for which the (N + 1) squared spherical sampling functions span the same linear manifold as do the spherical-harmonic functions through degree N. The transformations between the spherical sampling functions and the spherical-harmonic functions are given by recurrence relations. The spherical sampling functions of two arguments are extended to three arguments and to nonspherical reference surfaces. Typical applications of this formalism to geophysical topics are sketched.
Filter function synthesis by Gegenbauer generating function
Directory of Open Access Journals (Sweden)
Pavlović Vlastimir D.
2006-01-01
Full Text Available Low-pass all-pole transfer functions with non-monotonic amplitude characteristic in the pass-band and at least (n -1 flatness conditions for ω = 0 are considered in this paper. A new class of filters in explicit form with one free parameter is obtained by applying generating functions of Gegenbauer polynomials. This class of filters has good selectivity and good shape of amplitude characteristics in the pass-band. The amplitude characteristics of these transfer functions have gain in the upper part of pass-band with respect to the gain for ω = 0. This way we have greater margin of attenuation in the upper part of the pass-band. This means a greater tolerance of elements or for elements with given tolerances, greater ambient temperature changes. The appropriate choice of the free parameter enables us to generate filter functions obtained with Chebyshev polynomials of the first and second kind and Legendre polynomials.
DEFF Research Database (Denmark)
Markvorsen, Steen
2007-01-01
We consider a specific function of two variables whose graph surface resembles a blue lagoon. The function has a saddle point $p$, but when the function is restricted to any given straight line through $p$ it has a {\\em{strict local minimum}} along that line at $p$.......We consider a specific function of two variables whose graph surface resembles a blue lagoon. The function has a saddle point $p$, but when the function is restricted to any given straight line through $p$ it has a {\\em{strict local minimum}} along that line at $p$....
Functionalized boron nitride nanotubes
Sainsbury, Toby; Ikuno, Takashi; Zettl, Alexander K
2014-04-22
A plasma treatment has been used to modify the surface of BNNTs. In one example, the surface of the BNNT has been modified using ammonia plasma to include amine functional groups. Amine functionalization allows BNNTs to be soluble in chloroform, which had not been possible previously. Further functionalization of amine-functionalized BNNTs with thiol-terminated organic molecules has also been demonstrated. Gold nanoparticles have been self-assembled at the surface of both amine- and thiol-functionalized boron nitride Nanotubes (BNNTs) in solution. This approach constitutes a basis for the preparation of highly functionalized BNNTs and for their utilization as nanoscale templates for assembly and integration with other nanoscale materials.
Grabisch, Michel
2008-01-01
We extend the notion of belief function to the case where the underlying structure is no more the Boolean lattice of subsets of some universal set, but any lattice, which we will endow with a minimal set of properties according to our needs. We show that all classical constructions and definitions (e.g., mass allocation, commonality function, plausibility functions, necessity measures with nested focal elements, possibility distributions, Dempster rule of combination, decomposition w.r.t. simple support functions, etc.) remain valid in this general setting. Moreover, our proof of decomposition of belief functions into simple support functions is much simpler and general than the original one by Shafer.
DEFF Research Database (Denmark)
Thomsen, Søren Steffen
2009-01-01
Cryptographic hash functions are commonly used in many different areas of cryptography: in digital signatures and in public-key cryptography, for password protection and message authentication, in key derivation functions, in pseudo-random number generators, etc. Recently, cryptographic hash...... functions have received a huge amount of attention due to new attacks on widely used hash functions. This PhD thesis, having the title "Cryptographic Hash Functions", contains both a general description of cryptographic hash functions, including their applications and expected properties as well as some...
Scaled density functional theory correlation functionals.
Ghouri, Mohammed M; Singh, Saurabh; Ramachandran, B
2007-10-18
We show that a simple one-parameter scaling of the dynamical correlation energy estimated by the density functional theory (DFT) correlation functionals helps increase the overall accuracy for several local and nonlocal functionals. The approach taken here has been described as the "scaled dynamical correlation" (SDC) method [Ramachandran, J. Phys. Chem. A 2006, 110, 396], and its justification is the same as that of the scaled external correlation (SEC) method of Brown and Truhlar. We examine five local and five nonlocal (hybrid) DFT functionals, the latter group including three functionals developed specifically for kinetics by the Truhlar group. The optimum scale factors are obtained by use of a set of 98 data values consisting of molecules, ions, and transition states. The optimum scale factors, found with a linear regression relationship, are found to differ from unity with a high degree of correlation in nearly every case, indicating that the deviation of calculated results from the experimental values are systematic and proportional to the dynamic correlation energy. As a consequence, the SDC scaling of dynamical correlation decreases the mean errors (signed and unsigned) by significant amounts in an overwhelming majority of cases. These results indicate that there are gains to be realized from further parametrization of several popular exchange-correlation functionals.
Sun, Ying
2012-08-03
This article proposes functional median polish, an extension of univariate median polish, for one-way and two-way functional analysis of variance (ANOVA). The functional median polish estimates the functional grand effect and functional main factor effects based on functional medians in an additive functional ANOVA model assuming no interaction among factors. A functional rank test is used to assess whether the functional main factor effects are significant. The robustness of the functional median polish is demonstrated by comparing its performance with the traditional functional ANOVA fitted by means under different outlier models in simulation studies. The functional median polish is illustrated on various applications in climate science, including one-way and two-way ANOVA when functional data are either curves or images. Specifically, Canadian temperature data, U. S. precipitation observations and outputs of global and regional climate models are considered, which can facilitate the research on the close link between local climate and the occurrence or severity of some diseases and other threats to human health. © 2012 International Biometric Society.
Functionalized diamond nanoparticles
Beaujuge, Pierre M.
2014-10-21
A diamond nanoparticle can be functionalized with a substituted dienophile under ambient conditions, and in the absence of catalysts or additional reagents. The functionalization is thought to proceed through an addition reaction.
Lott, Steven
2015-01-01
This book is for developers who want to use Python to write programs that lean heavily on functional programming design patterns. You should be comfortable with Python programming, but no knowledge of functional programming paradigms is needed.
DEFF Research Database (Denmark)
Gardner, Richard J.; Kiderlen, Markus
A structural theory of operations between real-valued (or extended-real-valued) functions on a nonempty subset A of Rn is initiated. It is shown, for example, that any operation ∗ on a cone of functions containing the constant functions, which is pointwise, positively homogeneous, monotonic......, and associative, must be one of 40 explicitly given types. In particular, this is the case for operations between pairs of arbitrary, or continuous, or differentiable functions. The term pointwise means that (f ∗g)(x) = F(f(x), g(x)), for all x ∈ A and some function F of two variables. Several results in the same...... spirit are obtained for operations between convex functions or between support functions. For example, it is shown that ordinary addition is the unique pointwise operation between convex functions satisfying the identity property, i.e., f ∗ 0 = 0 ∗ f = f, for all convex f, while other results classify Lp...
... food, store energy, and remove poisons. Liver function tests are blood tests that check to see how well your liver ... hepatitis and cirrhosis. You may have liver function tests as part of a regular checkup. Or you ...
Pseudolinear functions and optimization
Mishra, Shashi Kant
2015-01-01
Pseudolinear Functions and Optimization is the first book to focus exclusively on pseudolinear functions, a class of generalized convex functions. It discusses the properties, characterizations, and applications of pseudolinear functions in nonlinear optimization problems.The book describes the characterizations of solution sets of various optimization problems. It examines multiobjective pseudolinear, multiobjective fractional pseudolinear, static minmax pseudolinear, and static minmax fractional pseudolinear optimization problems and their results. The authors extend these results to locally
Distributed processing; distributed functions?
Fox, Peter T.; FRISTON, KARL J
2012-01-01
After more than twenty years busily mapping the human brain, what have we learned from neuroimaging? This review (coda) considers this question from the point of view of structure–function relationships and the two cornerstones of functional neuroimaging; functional segregation and integration. Despite remarkable advances and insights into the brain’s functional architecture, the earliest and simplest challenge in human brain mapping remains unresolved: We do not have a principled way to map ...
Flammer, Carson
2005-01-01
Intended to facilitate the use and calculation of spheroidal wave functions, this applications-oriented text features a detailed and unified account of the properties of these functions. Addressed to applied mathematicians, mathematical physicists, and mathematical engineers, it presents tables that provide a convenient means for handling wave problems in spheroidal coordinates.Topics include separation of the scalar wave equation in spheroidal coordinates, angle and radial functions, integral representations and relations, and expansions in spherical Bessel function products. Additional subje
Energy Technology Data Exchange (ETDEWEB)
Korshunov, A D [S.L. Sobolev Institute for Mathematics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk (Russian Federation)
2003-10-31
Monotone Boolean functions are an important object in discrete mathematics and mathematical cybernetics. Topics related to these functions have been actively studied for several decades. Many results have been obtained, and many papers published. However, until now there has been no sufficiently complete monograph or survey of results of investigations concerning monotone Boolean functions. The object of this survey is to present the main results on monotone Boolean functions obtained during the last 50 years.
2015-01-01
This work aims at the exposition of two different results we have obtained in Functional Data Analysis. The first is a variable selection method in Functional Regression which is an adaptation of the well known Lasso technique. The second is a brand new Random Walk test for Functional Time Series. Being the results afferent to different areas of Functional Data Analysis, as well as of general Statistics, the introduction will be divided in three parts. Firstly we expose the fundament...
Feldman, Carol Fleisher
1977-01-01
Author advocates the view that meaning is necessarily dependent upon the communicative function of language and examines the objections, particularly those of Noam Chomsky, to this view. Argues that while Chomsky disagrees with the idea that communication is the essential function of language, he implicitly agrees that it has a function.…
Diplomacy and diplomatic functions
2011-01-01
Through the main lines of this study we try to introduce specific approaches of diplomacy, diplomatic mission, diplomatic visits and diplomatic functions. Functions of diplomacy: representation, negotiation, information, diplomatic protection, international cooperation, consular function have been developed and analyzed more in depth
Bates, Elizabeth; MacWhinney, Brian
A defense of functionalism in linguistics, and more specifically the competition model of linguistic performance, examines six misconceptions about the functionalist approach. Functionalism is defined as the belief that the forms of natural languages are created, governed, constrained, acquired, and used for communicative functions. Functionalism…
Degenerate Euler zeta function
Kim, Taekyun
2015-01-01
Recently, T. Kim considered Euler zeta function which interpolates Euler polynomials at negative integer (see [3]). In this paper, we study degenerate Euler zeta function which is holomorphic function on complex s-plane associated with degenerate Euler polynomials at negative integers.
Shabat, A. B.
2016-12-01
We consider the class of entire functions of exponential type in relation to the scattering theory for the Schrödinger equation with a finite potential that is a finite Borel measure. These functions have a special self-similarity and satisfy q-difference functional equations. We study their asymptotic behavior and the distribution of zeros.
Expanding Pseudorandom Functions
DEFF Research Database (Denmark)
Damgård, Ivan Bjerre; Nielsen, Jesper Buus
2002-01-01
Given any weak pseudorandom function, we present a general and efficient technique transforming such a function to a new weak pseudorandom function with an arbitrary length output. This implies, among other things, an encryption mode for block ciphers. The mode is as efficient as known (and widely...
Clinical functional MRI. Presurgical functional neuroimaging
Energy Technology Data Exchange (ETDEWEB)
Stippich, C. (ed.) [Heidelberg Univ. (Germany). Div. of Neuroradiology
2007-07-01
Functional magnetic resonance imaging (fMRI) permits noninvasive imaging of the ''human brain at work'' under physiological conditions. This is the first textbook on clinical fMRI. It is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery. State of the art fMRI procedures are presented, with detailed consideration of the physiological and methodological background, imaging and data processing, normal and pathological findings, diagnostic possibilities and limitations, and other related techniques. All chapters are written by recognized experts in their fields, and the book is designed to be of value to beginners, trained clinicians and experts alike. (orig.)
Hall, Joanne L; Donovan, Diane
2012-01-01
In 1980 Alltop produced a family of cubic phase sequences that nearly meet the Welch bound for maximum non-peak correlation magnitude. This family of sequences were shown by Wooters and Fields to be useful for quantum state tomography. Alltop's construction used a function that is not planar, but whose difference function is planar. In this paper we show that Alltop type functions cannot exist in fields of characteristic 3 and that for a known class of planar functions, $x^3$ is the only Alltop type function.
DEFF Research Database (Denmark)
Rosenstand, Claus Andreas Foss; Laursen, Per Kyed
2013-01-01
How does one manage functional power relations between leading functions in vision driven digital media creation, and this from idea to master during the creation cycle? Functional power is informal, and it is understood as roles, e.g. project manager, that provide opportunities to contribute...... to the product quality. The area of interest is the vision driven digital media industry in general; however, the point of departure is the game industry due to its aesthetic complexity. The article's contribution to the area is a power graph, which shows the functional power of the leading functions according...
Introduction to functional equations
Sahoo, Prasanna K
2011-01-01
Introduction to Functional Equations grew out of a set of class notes from an introductory graduate level course at the University of Louisville. This introductory text communicates an elementary exposition of valued functional equations where the unknown functions take on real or complex values. In order to make the presentation as manageable as possible for students from a variety of disciplines, the book chooses not to focus on functional equations where the unknown functions take on values on algebraic structures such as groups, rings, or fields. However, each chapter includes sections hig
The Cosmological Mass Function
Monaco, P
1997-01-01
This thesis aims to review the cosmological mass function problem, both from the theoretical and the observational point of view, and to present a new mass function theory, based on realistic approximations for the dynamics of gravitational collapse. Chapter 1 gives a general introduction on gravitational dynamics in cosmological models. Chapter 2 gives a complete review of the mass function theory. Chapters 3 and 4 present the ``dynamical'' mass function theory, based on truncated Lagrangian dynamics and on the excursion set approach. Chapter 5 reviews the observational state-of-the-art and the main applications of the mass function theories described before. Finally, Chapter 6 gives conclusions and future prospects.
Transfer function combinations
Zhou, Liang
2012-10-01
Direct volume rendering has been an active area of research for over two decades. Transfer function design remains a difficult task since current methods, such as traditional 1D and 2D transfer functions, are not always effective for all data sets. Various 1D or 2D transfer function spaces have been proposed to improve classification exploiting different aspects, such as using the gradient magnitude for boundary location and statistical, occlusion, or size metrics. In this paper, we present a novel transfer function method which can provide more specificity for data classification by combining different transfer function spaces. In this work, a 2D transfer function can be combined with 1D transfer functions which improve the classification. Specifically, we use the traditional 2D scalar/gradient magnitude, 2D statistical, and 2D occlusion spectrum transfer functions and combine these with occlusion and/or size-based transfer functions to provide better specificity. We demonstrate the usefulness of the new method by comparing to the following previous techniques: 2D gradient magnitude, 2D occlusion spectrum, 2D statistical transfer functions and 2D size based transfer functions. © 2012 Elsevier Ltd.
Multistate nested canalizing functions
Adeyeye, J O; Laubenbacher, R; Li, Y
2013-01-01
The concept of a nested canalizing Boolean function has been studied over the course of the last decade in the context of understanding the regulatory logic of molecular interaction networks, such as gene regulatory networks. Such functions appear preferentially in published models of such networks. Recently, this concept has been generalized to include multi-state functions, and a recursive formula has been derived for their number, as a function of the number of variables. This paper carries out a detailed analysis of the class of nested canalizing functions over an arbitrary finite field. Furthermore, the paper generalizes the concept further, and derives a closed formula for the number of such generalized functions. The paper also derives a closed formula for the number of equivalence classes under permutation of variables. This is motivated by the fact that two nested canalizing functions that differ by a permutation of the variables share many important properties with each other. The paper contributes ...
DEFF Research Database (Denmark)
Gauravaram, Praveen; Knudsen, Lars Ramkilde
2010-01-01
standard which will be referred to as SHA-3. This chapter studies hash functions. Several approaches to design hash functions are discussed. An overview of the generic attacks and short-cut attacks on the iterated hash functions is provided. Important hash function applications are described. Several hash......Cryptographic hash functions are an important tool of cryptography and play a fundamental role in efficient and secure information processing. A hash function processes an arbitrary finite length input message to a fixed length output referred to as the hash value. As a security requirement, a hash...... value should not serve as an image for two distinct input messages and it should be difficult to find the input message from a given hash value. Secure hash functions serve data integrity, non-repudiation and authenticity of the source in conjunction with the digital signature schemes. Keyed hash...
ALGEBROIDAL FUNCTION AND ITS DERIVED FUNCTION IN UNIT CIRCULAR DISC
Institute of Scientific and Technical Information of China (English)
Huo Yingying; Sun Daochun
2009-01-01
In this article, the authors define the derived function of an algeboidal function in the unit disc, prove it is an algabriodal function, and study the order of algebroidal function and that of its derived function in unit circular disc.
Directory of Open Access Journals (Sweden)
Anatoliy Klimyk
2007-02-01
Full Text Available In the paper, properties of antisymmetric orbit functions are reviewed and further developed. Antisymmetric orbit functions on the Euclidean space $E_n$ are antisymmetrized exponential functions. Antisymmetrization is fulfilled by a Weyl group, corresponding to a Coxeter-Dynkin diagram. Properties of such functions are described. These functions are closely related to irreducible characters of a compact semisimple Lie group $G$ of rank $n$. Up to a sign, values of antisymmetric orbit functions are repeated on copies of the fundamental domain $F$ of the affine Weyl group (determined by the initial Weyl group in the entire Euclidean space $E_n$. Antisymmetric orbit functions are solutions of the corresponding Laplace equation in $E_n$, vanishing on the boundary of the fundamental domain $F$. Antisymmetric orbit functions determine a so-called antisymmetrized Fourier transform which is closely related to expansions of central functions in characters of irreducible representations of the group $G$. They also determine a transform on a finite set of points of $F$ (the discrete antisymmetric orbit function transform. Symmetric and antisymmetric multivariate exponential, sine and cosine discrete transforms are given.
Counting with symmetric functions
Mendes, Anthony
2015-01-01
This monograph provides a self-contained introduction to symmetric functions and their use in enumerative combinatorics. It is the first book to explore many of the methods and results that the authors present. Numerous exercises are included throughout, along with full solutions, to illustrate concepts and also highlight many interesting mathematical ideas. The text begins by introducing fundamental combinatorial objects such as permutations and integer partitions, as well as generating functions. Symmetric functions are considered in the next chapter, with a unique emphasis on the combinatorics of the transition matrices between bases of symmetric functions. Chapter 3 uses this introductory material to describe how to find an assortment of generating functions for permutation statistics, and then these techniques are extended to find generating functions for a variety of objects in Chapter 4. The next two chapters present the Robinson-Schensted-Knuth algorithm and a method for proving Pólya’s enu...
Elliptic hypergeometric functions
Spiridonov, V P
2016-01-01
This is author's Habilitation Thesis (Dr. Sci. dissertation) submitted at the beginning of September 2004. It is written in Russian and is posted due to the continuing requests for the manuscript. The content: 1. Introduction, 2. Nonlinear chains with the discrete time and their self-similar solutions, 3. General theory of theta hypergeometric series, 4. Theta hypergeometric integrals, 5. Biorthogonal functions, 6. Elliptic hypergeometric functions with |q|=1, 7. Conclusion, 8. References. It contains an outline of a general heuristic scheme for building univariate special functions through self-similar reductions of spectral transformation chains, which allowed construction of the differential-difference q-Painleve equations, as well as of the most general known set of elliptic biorthogonal functions comprising all classical orthogonal polynomials and biorthogonal rational functions. One of the key results of the thesis consists in the discovery of genuinely transcendental elliptic hypergeometric functions d...
Engel, J
2006-01-01
The Hohenberg-Kohn theorem and Kohn-Sham procedure are extended to functionals of the localized intrinsic density of a self-bound system such as a nucleus. After defining the intrinsic-density functional, we modify the usual Kohn-Sham procedure slightly to evaluate the mean-field approximation to the functional, and carefully describe the construction of the leading corrections for a system of fermions in one dimension with a spin-degeneracy equal to the number of particles N. Despite the fact that the corrections are complicated and nonlocal, we are able to construct a local Skyrme-like intrinsic-density functional that, while different from the exact functional, shares with it a minimum value equal to the exact ground-state energy at the exact ground-state intrinsic density, to next-to-leading order in 1/N. We briefly discuss implications for real Skyrme functionals.
DEFF Research Database (Denmark)
Yazdani, Hossein; Ortiz-Arroyo, Daniel; Kwasnicka, Halina
2016-01-01
In data science, there are important parameters that affect the accuracy of the algorithms used. Some of these parameters are: the type of data objects, the membership assignments, and distance or similarity functions. This paper discusses similarity functions as fundamental elements in membership...... assignments. The paper introduces Weighted Feature Distance (WFD), and Prioritized Weighted Feature Distance (PWFD), two new distance functions that take into account the diversity in feature spaces. WFD functions perform better in supervised and unsupervised methods by comparing data objects on their feature...... spaces, in addition to their similarity in the vector space. Prioritized Weighted Feature Distance (PWFD) works similarly as WFD, but provides the ability to give priorities to desirable features. The accuracy of the proposed functions are compared with other similarity functions on several data sets...
1991-01-01
Researchers at the Balance Function Laboratory and Clinic at the Minneapolis (MN) Neuroscience Institute on the Abbot Northwestern Hospital Campus are using a rotational chair (technically a "sinusoidal harmonic acceleration system") originally developed by NASA to investigate vestibular (inner ear) function in weightlessness to diagnose and treat patients with balance function disorders. Manufactured by ICS Medical Corporation, Schaumberg, IL, the chair system turns a patient and monitors his or her responses to rotational stimulation.
Directory of Open Access Journals (Sweden)
Samo Drobne
2012-12-01
Full Text Available In the paper, we suggest an approach to evaluate the number and composition of functional regions. Suggested approach is based on basic characteristics of functional regions, that are (1 more intensive intra-regional than the inter-regional interactions and (2 internal social and economic heterogeneity. Those characteristics are measured by factors estimated in spatial interaction model. The approach to evaluate functional regions was applied to Slovenia for three time periods.
Pisani, Pablo
2015-01-01
We present a pedagogical exposition of some applications of functional methods in quantum field theory: we use heat-kernel and zeta-function techniques to study the Casimir effect, the pair production in strong electric fields, quantum fields at finite temperature and beta-functions for a self-interacting scalar field, QED and pure Yang-Mills theories. The more recent application to the UV/IR mixing phenomenon in noncommutative theories is also discussed in this framework.
DEFF Research Database (Denmark)
Rumessen, J J; Gudmand-Høyer, E
1988-01-01
Twenty-five patients with functional bowel disease were given fructose, sorbitol, fructose-sorbitol mixtures, and sucrose. The occurrence of malabsorption was evaluated by means of hydrogen breath tests and the gastrointestinal symptoms, if any, were recorded. One patient could not be evaluated...... with functional bowel disease. The findings may have direct influence on the dietary guidance given to a major group of patients with functional bowel disease and may make it possible to define separate entities in this disease complex....
Canteaut, Anne; Videau, Marion
2005-01-01
http://www.ieee.org/; We present an extensive study of symmetric Boolean functions, especially of their cryptographic properties. Our main result establishes the link between the periodicity of the simplified value vector of a symmetric Boolean function and its degree. Besides the reduction of the amount of memory required for representing a symmetric function, this property has some consequences from a cryptographic point of view. For instance, it leads to a new general bound on the order of...
Artin, Emil
2015-01-01
This brief monograph on the gamma function was designed by the author to fill what he perceived as a gap in the literature of mathematics, which often treated the gamma function in a manner he described as both sketchy and overly complicated. Author Emil Artin, one of the twentieth century's leading mathematicians, wrote in his Preface to this book, ""I feel that this monograph will help to show that the gamma function can be thought of as one of the elementary functions, and that all of its basic properties can be established using elementary methods of the calculus."" Generations of teachers
Institute of Scientific and Technical Information of China (English)
Ding Yi
2009-01-01
In this article, the author derives a functional equation η(s)=［(π/4)s-1/2√2/πг(1-s)sin(πs/2)]η(1-s) of the analytic function η(s) which is defined by η(s)=1-s-3-s-5-s+7-s…for complex variable s with Re s>1, and is defined by analytic continuation for other values of s. The author proves (1) by Ramanujan identity (see [1], [3]). Her method provides a new derivation of the functional equation of Riemann zeta function by using Poisson summation formula.
Quantum Iterated Function Systems
Lozinski, A; Slomczynski, W; Lozinski, Artur; Zyczkowski, Karol; Slomczynski, Wojciech
2003-01-01
Iterated functions system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on the initial point. In an analogous way, we define quantum iterated functions system (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting a QIFS consists of completely positive maps acting in the space of density operators. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant state.
DEFF Research Database (Denmark)
Raket, Lars Lau
-effect formulations, where the observed functional signal is assumed to consist of both fixed and random functional effects. This thesis takes the initial steps toward the development of likelihood-based methodology for functional objects. We first consider analysis of functional data defined on high......-dimensional Euclidean spaces under the effect of additive spatially correlated effects, and then move on to consider how to include data alignment in the statistical model as a nonlinear effect under additive correlated noise. In both cases, we will give directions on how to generalize the methodology to more complex...
Functional foods in pediatrics.
Van den Driessche, M; Veereman-Wauters, G
2002-01-01
The philosophy that food can be health promoting beyond its nutritional value is gaining acceptance. Known disease preventive aspects of nutrition have led to a new science, the 'functional food science'. Functional foods, first introduced in Japan, have no universally accepted definition but can be described as foods or food ingredients that may provide health benefits and prevent diseases. Currently, there is a growing interest in these products. However, not all regulatory issues have been settled yet. Five categories of foods can be classified as functional foods: dietary fibers, vitamins and minerals, bioactive substances, fatty acids and pro-, pre- and symbiotics. The latter are currently the main focus of research. Functional foods can be applied in pediatrics: during pregnancy, nutrition is 'functional' since it has prenatal influences on the intra-uterine development of the baby, after birth, 'functional' human milk supports adequate growth of infants and pro- and prebiotics can modulate the flora composition and as such confer certain health advantages. Functional foods have also been studied in pediatric diseases. The severity of necrotising enterocolitis (NEC), diarrhea, irritable bowel syndrome, intestinal allergy and lactose intolerance may be reduced by using functional foods. Functional foods have proven to be valuable contributors to the improvement of health and the prevention of diseases in pediatric populations.
DEFF Research Database (Denmark)
Törpel, Bettina
2006-01-01
The objective of this paper is the design of computer supported joint action spaces. It is argued against a view of functionality as residing in computer applications. In such a view the creation of functionality is equivalent to the creation of computer applications. Functionality, in the view...... advocated in this paper, emerges in the specific dynamic interplay of actors, objectives, structures, practices and means. In this view, functionality is the result of creating, harnessing and inhabiting computer supported joint action spaces. The successful creation and further development of a computer...
Functional Nausea in Children.
Kovacic, Katja; Di Lorenzo, Carlo
2016-03-01
Chronic nausea is a highly prevalent, bothersome, and difficult-to-treat symptom among adolescents. When chronic nausea presents as the predominant symptom and is not associated with any underlying disease, it may be considered a functional gastrointestinal disorder and named "functional nausea." The clinical features of functional nausea and its association with comorbid conditions provide clues to the underlying pathophysiological mechanisms. These may include gastrointestinal motor and sensory disturbances, autonomic imbalance, altered central nervous system pathways, or a combination of these. This review summarizes the current knowledge on mechanisms and treatment strategies for chronic, functional nausea in children.
DEFF Research Database (Denmark)
Lind, Morten
2011-01-01
Multilevel Flow Modeling (MFM) has been proposed as a tool for representing goals and functions of complex industrial plants and suggested as a basis for reasoning about control situations. Lind presents an introduction to MFM but do not describe how control functions are used in the modeling....... The purpose of the present paper is to serve as a companion paper to this introduction by explaining the basic principles used in MFM for representation of control functions. A theoretical foundation for modeling control functions is presented and modeling examples are given for illustration....
Perceptual Audio Hashing Functions
Directory of Open Access Journals (Sweden)
Emin Anarım
2005-07-01
Full Text Available Perceptual hash functions provide a tool for fast and reliable identification of content. We present new audio hash functions based on summarization of the time-frequency spectral characteristics of an audio document. The proposed hash functions are based on the periodicity series of the fundamental frequency and on singular-value description of the cepstral frequencies. They are found, on one hand, to perform very satisfactorily in identification and verification tests, and on the other hand, to be very resilient to a large variety of attacks. Moreover, we address the issue of security of hashes and propose a keying technique, and thereby a key-dependent hash function.
Knopp, Konrad
1996-01-01
This is a one-volume edition of Parts I and II of the classic five-volume set The Theory of Functions prepared by renowned mathematician Konrad Knopp. Concise, easy to follow, yet complete and rigorous, the work includes full demonstrations and detailed proofs.Part I stresses the general foundation of the theory of functions, providing the student with background for further books on a more advanced level.Part II places major emphasis on special functions and characteristic, important types of functions, selected from single-valued and multiple-valued classes.
Luten, J.B.
2009-01-01
This book reviews the research on seafood and health, the use and quality aspects of marine lipids and seafood proteins as ingredients in functional foods and consumer acceptance of (marine) functional food. The first chapter covers novel merging areas where seafood may prevent disease and improve h
Thyroid function in pregnancy☆
Leung, Angela M.
2012-01-01
Iodine is required for the production of thyroid hormones. Normal thyroid function during pregnancy is important for both the mother and developing fetus. This review discusses the changes in thyroid physiology that occur during pregnancy, the significance of thyroid function tests and thyroid antibody titers assessed during pregnancy, and the potential obstetric complications associated with maternal hypothyroidism.
Construction of Resilient Functions
Institute of Scientific and Technical Information of China (English)
ZHANG Jie; WEN Qiao-yan
2005-01-01
Based on the relationship between nonlinearity and resiliency of a multi-output function, we present a method for constructing nonintersecting linear codes from packing design. Through these linear codes, we obtain n-variable, moutput, t-resilient functions with very high nonlinearity.Their nonlinearities are currently the best results for most of cases.
Khimshiashvili, G.; Siersma, D.
2001-01-01
We describe the structure of minimal round functions on closed surfaces and three-folds. The minimal possible number of critical loops is determined and typical non-equisingular round function germs are interpreted in the spirit of isolated line singularities. We also discuss a version of Lusternik-
Institute of Scientific and Technical Information of China (English)
HAN You-fa; YAN Xin-ming; LV Li-li
2012-01-01
In this paper,we discuss the properties of the colored Jones function of knots.Particularly,we calculate the colored Jones function of some knots(31,41,51,52).Furthermore,one can compute the Kashaev's invariants and study some properties of the Kashaev's conjecture.
Functional and cognitive grammars
Institute of Scientific and Technical Information of China (English)
Anna Siewierska
2011-01-01
This paper presents a comprehensive review of the functional approach and cognitive approach to the nature of language and its relation to other aspects of human cognition. The paper starts with a brief discussion of the origins and the core tenets of the two approaches in Section 1. Section 2 discusses the similarities and differences between the three full-fledged structural functional grammars subsumed in the functional approach： Halliday＇s Systemic Functional Grammar （SFG）, Dik＇s Functional Grammar （FG）, and Van Valin＇s Role and Reference Grammar （RRG）. Section 3 deals with the major features of the three cognitive frameworks： Langacker＇s Cognitive Grammar （CG）, Goldberg＇s Cognitive Construction Grammar （CCG）, and Croft＇s Radical Construction Grammar （RCG）. Section 4 compares the two approaches and attempts to provide a unified functional-cognitive grammar. In the last section, the author concludes the paper with remarks on the unidirectional shift from functional grammar to cognitive grammar that may indicate a reinterpretation of the traditional relationship between functional and cognitive models of grammar.
Distribution Functions of Copulas
Institute of Scientific and Technical Information of China (English)
LI Yong-hong; He Ping
2007-01-01
A general method was proposed to evaluate the distribution function of 〈C1|C2〉 . Some examples were presented to validate the application of the method. Then the sufficient and necessary condition for that the distribution function ofis uniform was proved.
Pick, Luboš; John, Oldrich; Fucík, Svatopluk
2012-01-01
This is the first part of the second revised and extended edition of a well established monograph. It is an introduction to function spaces defined in terms of differentiability and integrability classes. It provides a catalogue of various spaces and benefits as a handbook for those who use function spaces to study other topics such as partial differential equations. Volum
DEFF Research Database (Denmark)
Yazdani, Hossein; Ortiz-Arroyo, Daniel; Kwasnicka, Halina
2016-01-01
In data science, there are important parameters that affect the accuracy of the algorithms used. Some of these parameters are: the type of data objects, the membership assignments, and distance or similarity functions. This paper discusses similarity functions as fundamental elements in membership...
Institute of Scientific and Technical Information of China (English)
王雷
2008-01-01
<正>EXAMPLE 1 Determining Wheth- er a Relation Represents a Function. Determining whether the following relation represent functions. (a)For this relation, the domain represents the employee of Saraxvs Pre -Owner Car Mart and the range repre- sents their base salary.
Ranu, H; Wilde, M.; Madden, B
2011-01-01
Pulmonary function tests are valuable investigations in the management of patients with suspected or previously diagnosed respiratory disease. They aid diagnosis, help monitor response to treatment and can guide decisions regarding further treatment and intervention. The interpretation of pulmonary functions tests requires knowledge of respiratory physiology. In this review we describe investigations routinely used and discuss their clinical implications.
Fundamentals of Functional Analysis
Kutateladze, S S; Slovák, Jan
2001-01-01
A concise guide to basic sections of modern functional analysis. Included are such topics as the principles of Banach and Hilbert spaces, the theory of multinormed and uniform spaces, the Riesz-Dunford holomorphic functional calculus, the Fredholm index theory, convex analysis and duality theory for locally convex spaces with applications to the Schwartz spaces of distributions and Radon measures.
Functional Magnetic Resonance Imaging
Voos, Avery; Pelphrey, Kevin
2013-01-01
Functional magnetic resonance imaging (fMRI), with its excellent spatial resolution and ability to visualize networks of neuroanatomical structures involved in complex information processing, has become the dominant technique for the study of brain function and its development. The accessibility of in-vivo pediatric brain-imaging techniques…
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
A new characterization of univalent Bloch functions is given by investigating the growth order of an essentially increasing function. Our contribution can be considered as a slight improvement of the well-known Pommerenke's result and its all generalizations, and the proof presented in this paper is independently developed.
Monadic Functional Reactive Programming
Ploeg, A.J. van der; Shan, C
2013-01-01
Functional Reactive Programming (FRP) is a way to program reactive systems in functional style, eliminating many of the problems that arise from imperative techniques. In this paper, we present an alternative FRP formulation that is based on the notion of a reactive computation: a monadic computatio
A Functional HAZOP Methodology
DEFF Research Database (Denmark)
Liin, Netta; Lind, Morten; Jensen, Niels;
2010-01-01
A HAZOP methodology is presented where a functional plant model assists in a goal oriented decomposition of the plant purpose into the means of achieving the purpose. This approach leads to nodes with simple functions from which the selection of process and deviation variables follow directly....... The functional HAZOP methodology lends itself directly for implementation into a computer aided reasoning tool to perform root cause and consequence analysis. Such a tool can facilitate finding causes and/or consequences far away from the site of the deviation. A functional HAZOP assistant is proposed...... and investigated in a HAZOP study of an industrial scale Indirect Vapor Recompression Distillation pilot Plant (IVaRDiP) at DTU-Chemical and Biochemical Engineering. The study shows that the functional HAZOP methodology provides a very efficient paradigm for facilitating HAZOP studies and for enabling reasoning...
Submodular functions and optimization
Fujishige, Satoru
2005-01-01
It has widely been recognized that submodular functions play essential roles in efficiently solvable combinatorial optimization problems. Since the publication of the 1st edition of this book fifteen years ago, submodular functions have been showing further increasing importance in optimization, combinatorics, discrete mathematics, algorithmic computer science, and algorithmic economics, and there have been made remarkable developments of theory and algorithms in submodular functions. The 2nd edition of the book supplements the 1st edition with a lot of remarks and with new two chapters: "Submodular Function Minimization" and "Discrete Convex Analysis." The present 2nd edition is still a unique book on submodular functions, which is essential to students and researchers interested in combinatorial optimization, discrete mathematics, and discrete algorithms in the fields of mathematics, operations research, computer science, and economics. Key features: - Self-contained exposition of the theory of submodular ...
Implementing function spreadsheets
DEFF Research Database (Denmark)
Sestoft, Peter
2008-01-01
A large amount of end-user development is done with spreadsheets. The spreadsheet metaphor is attractive because it is visual and accommodates interactive experimentation, but as observed by Peyton Jones, Blackwell and Burnett, the spreadsheet metaphor does not admit even the most basic abstraction......: that of turning an expression into a named function. Hence they proposed a way to define a function in terms of a worksheet with designated input and output cells; we shall call it a function sheet. The goal of our work is to develop implementations of function sheets and study their application to realistic...... examples. Therefore, we are also developing a simple yet comprehensive spreadsheet core implementation for experimentation with this technology. Here we report briefly on our experiments with function sheets as well as other uses of our spreadsheet core implementation....
Wu, Xiang-Yao; Yang, Jing-Hai; Liu, Xiao-Jing; Ba, Nuo; Wu, Yi-Heng; Wang, Qing-Cai; Li, Jing-Wu
2010-01-01
In the paper, we present a new kind of function photonic crystals, which refractive index is a function of space position. Unlike conventional PCs, which structure grow from two materials, A and B, with different dielectric constants $\\epsilon_{A}$ and $\\epsilon_{B}$. By Fermat principle, we give the motion equations of light in one-dimensional, two-dimensional and three-dimensional function photonic crystals. For one-dimensional function photonic crystals, we study the dispersion relation, band gap structure and transmissivity, and compare them with conventional photonic crystals. By choosing various refractive index distribution function $n(z)$, we can obtain more width or more narrow band gap structure than conventional photonic crystals.
properties and luminosity functions
Directory of Open Access Journals (Sweden)
Hektor Monteiro
2007-01-01
Full Text Available In this article, we present an investigation of a sample of 1072 stars extracted from the Villanova Catalog of Spectroscopically Identified White Dwarfs (2005 on-line version, studying their distribution in the Galaxy, their physical properties and their luminosity functions. The distances and physical properties of the white dwarfs are determined through interpolation of their (B-V or (b-y colors in model grids. The solar position relative to the Galactic plane, luminosity function, as well as separate functions for each white dwarf spectral type are derived and discussed. We show that the binary fraction does not vary significantly as a function of distance from the Galactic disk out to 100 pc. We propose that the formation rates of DA and non-DAs have changed over time and/or that DAs evolve into non-DA types. The luminosity functions for DAs and DBs have peaks possibly related to a star burst event.
Ramsay, J O
1997-01-01
Scientists today collect samples of curves and other functional observations. This monograph presents many ideas and techniques for such data. Included are expressions in the functional domain of such classics as linear regression, principal components analysis, linear modelling, and canonical correlation analysis, as well as specifically functional techniques such as curve registration and principal differential analysis. Data arising in real applications are used throughout for both motivation and illustration, showing how functional approaches allow us to see new things, especially by exploiting the smoothness of the processes generating the data. The data sets exemplify the wide scope of functional data analysis; they are drwan from growth analysis, meterology, biomechanics, equine science, economics, and medicine. The book presents novel statistical technology while keeping the mathematical level widely accessible. It is designed to appeal to students, to applied data analysts, and to experienced researc...
DEFF Research Database (Denmark)
Sørensen, A S; Hansen, H; Høgenhaven, H;
1988-01-01
served as controls: 15 patients with a non-neurological but relapsing disorder, psoriasis, and 15 healthy volunteers. Compared with the group of healthy volunteers, a decreased adaptive level of ego functioning was found in the epilepsy groups, regardless of seizure types and EEG findings, and......, to a lesser extent, compared with the psoriasis group. Areas of ego functioning most affected were "reality testing", "cognitive functioning", "integrative functioning" and "regulation and control of drives". Patients with more than one type of seizure were the most affected, as were patients who were younger...... than 15 years when the disease began. The number of anticonvulsants administered did not influence the results. No difference on adaptive level of ego functioning was found between the group with primary generalized epilepsy and the group with temporal lobe epilepsy. Similarly, the temporal lobe...
Minguzzi, E.
2010-09-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K + relation (Seifert’s relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg’s and Levin’s theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K + (or Seifert) relation which indeed turns out to be the intersection of the time or temporal orderings. This result tells us in which circumstances it is possible to recover the chronological or causal relation starting from the set of time or temporal functions allowed by the spacetime. Moreover, it is proved that a chronological spacetime in which the closure of the causal relation is transitive (for instance a reflective spacetime) admits a semi-time function. Along the way a new proof avoiding smoothing techniques is given that the existence of a time function implies stable causality, and a new short proof of the equivalence between K-causality and stable causality is given which takes advantage of Levin’s theorem and smoothing techniques.
Balcan, Maria-Florina
2010-01-01
There has recently been significant interest in the machine learning community on understanding and using submodular functions. Despite this recent interest, little is known about submodular functions from a learning theory perspective. Motivated by applications such as pricing goods in economics, this paper considers PAC-style learning of submodular functions in a distributional setting. A problem instance consists of a distribution on {0,1}^n and a real-valued function on {0,1}^n that is non-negative, monotone and submodular. We are given poly(n) samples from this distribution, along with the values of the function at those sample points. The task is to approximate the value of the function to within a multiplicative factor at subsequent sample points drawn from the same distribution, with sufficiently high probability. We prove several results for this problem. (1) If the function is Lipschitz and the distribution is a product distribution, such as the uniform distribution, then a good approximation is pos...
Minguzzi, E
2009-01-01
Every time function on spacetime gives a (continuous) total preordering of the spacetime events which respects the notion of causal precedence. The problem of the existence of a (semi-)time function on spacetime and the problem of recovering the causal structure starting from the set of time functions are studied. It is pointed out that these problems have an analog in the field of microeconomics known as utility theory. In a chronological spacetime the semi-time functions correspond to the utilities for the chronological relation, while in a K-causal (stably causal) spacetime the time functions correspond to the utilities for the K^+ relation (Seifert's relation). By exploiting this analogy, we are able to import some mathematical results, most notably Peleg's and Levin's theorems, to the spacetime framework. As a consequence, we prove that a K-causal (i.e. stably causal) spacetime admits a time function and that the time or temporal functions can be used to recover the K^+ (or Seifert) relation which indeed...
Unification of Filled Function and Tunnelling Function in Global Optimization
Institute of Scientific and Technical Information of China (English)
Wei Wang; Yong-jian Yang; Lian-sheng Zhang
2007-01-01
In this paper, two auxiliary functions for global optimization are proposed. These two auxiliary functions possess all characters of tunnelling functions and filled functions under certain general assumptions.Thus, they can be considered as the unification of filled function and tunnelling function. Moreover, the process of tunneling or filling for global optimization can be unified as the minimization of such auxiliary functions.Result of numerical experiments shows that such two auxiliary functions are effective.
Mathai, AM
2009-01-01
The two main topics emphasized in this book, special functions and fractional calculus, are currently under fast development in theory and application to many problems in statistics, physics, and engineering, particularly in condensed matter physics, plasma physics, and astrophysics. The book begins by setting forth definitions, contours, existence conditions, and particular cases of the H-function. The authors then deal with Laplace, Fourier, Hankel, and other transforms. As these relations are explored, fractional calculus and its relations to H-functions emerge with important results on fra
Luke, Yudell L
2014-01-01
Integrals of Bessel Functions concerns definite and indefinite integrals, the evaluation of which is necessary to numerous applied problems. A massive compendium of useful information, this volume represents a resource for applied mathematicians in many areas of academia and industry as well as an excellent text for advanced undergraduates and graduate students of mathematics.Starting with an extensive introductory chapter on basic formulas, the treatment advances to indefinite integrals, examining them in terms of Lommel and Bessel functions. Subsequent chapters explore airy functions, incomp
Quantum iterated function systems.
Łoziński, Artur; Zyczkowski, Karol; Słomczyński, Wojciech
2003-10-01
An iterated function system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on an initial point. In an analogous way, we define a quantum IFS (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting, a QIFS consists of completely positive maps acting in the space of density operators. This formalism is designed to describe certain problems of nonunitary quantum dynamics. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant states.
Directory of Open Access Journals (Sweden)
Carlos A. Berenstein
1980-01-01
Full Text Available We show that any mean-periodic function f can be represented in terms of exponential-polynomial solutions of the same convolution equation f satisfies, i.e., u∗f=0(μ∈E′(ℝn. This extends to n-variables the work of L. Schwartz on mean-periodicity and also extends L. Ehrenpreis' work on partial differential equations with constant coefficients to arbitrary convolutors. We also answer a number of open questions about mean-periodic functions of one variable. The basic ingredient is our work on interpolation by entire functions in one and several complex variables.
Correlation Functions and Spin
Tyc, T
2000-01-01
The k-electron correlation function of a free chaotic electron beam is derived with the spin degree of freedom taken into account. It is shown that it can be expressed with the help of correlation functions for a polarized electron beam of all orders up to k and the degree of spin polarization. The form of the correlation function suggests that if the electron beam is not highly polarized, observing multi-particle correlations should be difficult. The result can be applied also to chaotic photon beams, the degree of spin polarization being replaced by the degree of polarization.
DEFF Research Database (Denmark)
Sørensen, A S; Hansen, H; Høgenhaven, H;
1988-01-01
Two groups of epilepsy patients (28 patients with temporal lobe epilepsy and 15 patients with primary generalized epilepsy) entered a study of personality traits related to epilepsy, based on a modification of Bellak's semistructured interview for assessment of ego strength. Two groups of subjects......, to a lesser extent, compared with the psoriasis group. Areas of ego functioning most affected were "reality testing", "cognitive functioning", "integrative functioning" and "regulation and control of drives". Patients with more than one type of seizure were the most affected, as were patients who were younger...
Choice probability generating functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2010-01-01
This paper establishes that every random utility discrete choice model (RUM) has a representation that can be characterized by a choice-probability generating function (CPGF) with specific properties, and that every function with these specific properties is consistent with a RUM. The choice...... probabilities from the RUM are obtained from the gradient of the CPGF. Mixtures of RUM are characterized by logarithmic mixtures of their associated CPGF. The paper relates CPGF to multivariate extreme value distributions, and reviews and extends methods for constructing generating functions for applications...
Catalytic Functions of Standards
K. Blind (Knut)
2009-01-01
textabstractThe three different areas and the examples have illustrated several catalytic functions of standards for innovation. First, the standardisation process reduces the time to market of inventions, research results and innovative technologies. Second, standards themselves promote the diffusi
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Rechberger, Christian; Thomsen, Søren Steffen
2007-01-01
In this paper we propose the Grindahl hash functions, which are based on components of the Rijndael algorithm. To make collision search sufficiently difficult, this design has the important feature that no low-weight characteristics form collisions, and at the same time it limits access to the st......In this paper we propose the Grindahl hash functions, which are based on components of the Rijndael algorithm. To make collision search sufficiently difficult, this design has the important feature that no low-weight characteristics form collisions, and at the same time it limits access...... to the state. We propose two concrete hash functions, Grindahl-256 and Grindahl-512 with claimed security levels with respect to collision, preimage and second preimage attacks of 2^128 and 2^256, respectively. Both proposals have lower memory requirements than other hash functions at comparable speeds...
Campos, Cédric M.; Epstein, Marcelo; De León, Manuel
2007-01-01
The notions of uniformity and homogeneity of elastic materials are reviewed in terms of Lie groupoids and frame bundles. This framework is also extended to consider the case Functionally Graded Media, which allows us to obtain some homogeneity conditions.
... Spread the Word Shop AAP Find a Pediatrician Family Life Medical Home Family Dynamics Adoption & Foster Care ... Español Text Size Email Print Share Normal Functioning Family Page Content Article Body Is there any way ...
The methods used seem to be new, and the author feels that further work in this direction may eventually yield a proof of the conjecture in the case when one of the functions is of bounded variation . (Author)
Pair Correlation Function Integrals
DEFF Research Database (Denmark)
Wedberg, Nils Hejle Rasmus Ingemar; O'Connell, John P.; Peters, Günther H.J.;
2011-01-01
numerical tests complementing previous results. Pure molecular fluids are here studied in the isothermal-isobaric ensemble with isothermal compressibilities evaluated from the total correlation function integrals and compared with values derived from volume fluctuations. For systems where the radial......We describe a method for extending radial distribution functions obtained from molecular simulations of pure and mixed molecular fluids to arbitrary distances. The method allows total correlation function integrals to be reliably calculated from simulations of relatively small systems. The long......, and J. Abildskov, Mol. Simul. 36, 1243 (2010); Fluid Phase Equilib. 302, 32 (2011)], but describe here its theoretical basis more thoroughly and derive long-distance approximations for the direct correlation functions. We describe the numerical implementation of the method in detail, and report...
The Protostellar Luminosity Function
Offner, Stella
2011-01-01
The protostellar luminosity function (PLF) is the present-day luminosity function of the protostars in a region of star formation. It is determined using the protostellar mass function (PMF) in combination with a stellar evolutionary model that provides the luminosity as a function of instantaneous and final stellar mass. As in McKee & Offner (2010), we consider three main accretion models: the Isothermal Sphere model, the Turbulent Core model, and an approximation of the Competitive Accretion model. We also consider the effect of an accretion rate that tapers off linearly in time and an accelerating star formation rate. For each model, we characterize the luminosity distribution using the mean, median, maximum, ratio of the median to the mean, standard deviation of the logarithm of the luminosity, and the fraction of very low luminosity objects. We compare the models with bolometric luminosities observed in local star forming regions and find that models with an approximately constant accretion time, suc...
Fundamentals of functional analysis
Farenick, Douglas
2016-01-01
This book provides a unique path for graduate or advanced undergraduate students to begin studying the rich subject of functional analysis with fewer prerequisites than is normally required. The text begins with a self-contained and highly efficient introduction to topology and measure theory, which focuses on the essential notions required for the study of functional analysis, and which are often buried within full-length overviews of the subjects. This is particularly useful for those in applied mathematics, engineering, or physics who need to have a firm grasp of functional analysis, but not necessarily some of the more abstruse aspects of topology and measure theory normally encountered. The reader is assumed to only have knowledge of basic real analysis, complex analysis, and algebra. The latter part of the text provides an outstanding treatment of Banach space theory and operator theory, covering topics not usually found together in other books on functional analysis. Written in a clear, concise manner,...
Lectures on Functional Analysis
Kurepa, Svetozar; Kraljević, Hrvoje
1987-01-01
This volume consists of a long monographic paper by J. Hoffmann-Jorgensen and a number of shorter research papers and survey articles covering different aspects of functional analysis and its application to probability theory and differential equations.
1991-01-01
The concepts of source and quantum action principle are used to produce the phonon Green's function appropriate for an initial phonon vacuum state. An application to the Mossbauer effect is presented.
[Vascular endothelial Barrier Function].
Ivanov, A N; Puchinyan, D M; Norkin, I A
2015-01-01
Endothelium is an important regulator of selective permeability of the vascular wall for different molecules and cells. This review summarizes current data on endothelial barrier function. Endothelial glycocalyx structure, its function and role in the molecular transport and leukocytes migration across the endothelial barrier are discussed. The mechanisms of transcellular transport of macromolecules and cell migration through endothelial cells are reviewed. Special section of this article addresses the structure and function of tight and adherens endothelial junction, as well as their importance for the regulation of paracellular transport across the endothelial barrier. Particular attention is paid to the signaling mechanism of endothelial barrier function regulation and the factors that influence on the vascular permeability.
On Network Functional Compression
Feizi, Soheil
2010-01-01
In this paper, we consider different aspects of the network functional compression problem where computation of a function (or, some functions) of sources located at certain nodes in a network is desired at receiver(s). The rate region of this problem has been considered in the literature under certain restrictive assumptions, particularly in terms of the network topology, the functions and the characteristics of the sources. In this paper, we present results that significantly relax these assumptions. Firstly, we consider this problem for an arbitrary tree network and asymptotically lossless computation. We show that, for depth one trees with correlated sources, or for general trees with independent sources, a modularized coding scheme based on graph colorings and Slepian-Wolf compression performs arbitrarily closely to rate lower bounds. For a general tree network with independent sources, optimal computation to be performed at intermediate nodes is derived. We introduce a necessary and sufficient condition...
Kellerstein, M; Verbaarschot, J J M
2016-01-01
The behavior of quenched Dirac spectra of two-dimensional lattice QCD is consistent with spontaneous chiral symmetry breaking which is forbidden according to the Coleman-Mermin-Wagner theorem. One possible resolution of this paradox is that, because of the bosonic determinant in the partially quenched partition function, the conditions of this theorem are violated allowing for spontaneous symmetry breaking in two dimensions or less. This goes back to work by Niedermaier and Seiler on nonamenable symmetries of the hyperbolic spin chain and earlier work by two of the auhtors on bosonic partition functions at nonzero chemical potential. In this talk we discuss chiral symmetry breaking for the bosonic partition function of QCD at nonzero isospin chemical potential and a bosonic random matrix theory at imaginary chemical potential and compare the results with the fermionic counterpart. In both cases the chiral symmetry group of the bosonic partition function is noncompact.
Bioprinting: Functional droplet networks
Durmus, Naside Gozde; Tasoglu, Savas; Demirci, Utkan
2013-06-01
Tissue-mimicking printed networks of droplets separated by lipid bilayers that can be functionalized with membrane proteins are able to spontaneously fold and transmit electrical currents along predefined paths.
ON BANDLIMITED SCALING FUNCTION
Institute of Scientific and Technical Information of China (English)
Wei Chen; Qiao Yang; Wei-jun Jiang; Si-long Peng
2002-01-01
This paper discuss band-limited scaling function, especially on the interval band case and three interval bands case, its relationship to oversampling property and weakly translation invariance are also studied. At the end, we propose an open problem.
Holographic Three point Functions
DEFF Research Database (Denmark)
Bissi, Agnese
In this thesis it is addressed the problem of the computation of three point correlation functions within the AdS=CFT correspondence. In the context of the AdS 5=CFT4 correspondence we present three computations. First we compare the results of tree level three point functions of two giant...... gravitons and a point like graviton and its dual counterpart, namely two Schur polynomials and a single trace chiral primary. Secondly we compute the one loop correction to planar, non extremal three point functions of two heavy and one light operators, both from the gauge and string side in the Frolov......-Tseytlin regime. Finally we generalize the scalar product of two states belonging to the SO(6) sector of N = 4 SYM with implications on the construction of three point functions of 3 non-BPS operators from the gauge theory side. On the other hand in the AdS4=CFT3 correspondence we compare the computations...
Directory of Open Access Journals (Sweden)
N. Carella
2013-09-01
Full Text Available A new unconditional inequality of the totient function is contributed to the literature. This result is associated with various unsolved problems about the distribution of prime numbers.
Characterisation of Functional Surfaces
DEFF Research Database (Denmark)
Lonardo, P.M.; De Chiffre, Leonardo; Bruzzone, A.A.
2004-01-01
Characterisation of surfaces is of fundamental importance to control the manufacturing process and the functional performance of the part. Many applications concern contact and tribology problems, which include friction, wear and lubrication. This paper presents the techniques and instruments for...
Center for Functional Nanomaterials
Federal Laboratory Consortium — The Center for Functional Nanomaterials (CFN) explores the unique properties of materials and processes at the nanoscale. The CFN is a user-oriented research center...
Functional Task Test: Data Review
Cromwell, Ronita
2014-01-01
After space flight there are changes in multiple physiological systems including: Cardiovascular function; Sensorimotor function; and Muscle function. How do changes in these physiological system impact astronaut functional performance?
Roy D Sleator
2012-01-01
An overwhelming array of structural variants has evolved from a comparatively small number of protein structural domains; which has in turn facilitated an expanse of functional derivatives. Herein, I review the primary mechanisms which have contributed to the vastness of our existing, and expanding, protein repertoires. Protein function prediction strategies, both sequence and structure based, are also discussed and their associated strengths and weaknesses assessed.
Griffel, DH
2002-01-01
A stimulating introductory text, this volume examines many important applications of functional analysis to mechanics, fluid mechanics, diffusive growth, and approximation. Detailed enough to impart a thorough understanding, the text is also sufficiently straightforward for those unfamiliar with abstract analysis. Its four-part treatment begins with distribution theory and discussions of Green's functions. Essentially independent of the preceding material, the second and third parts deal with Banach spaces, Hilbert space, spectral theory, and variational techniques. The final part outlines the
Green's functions with applications
Duffy, Dean G
2015-01-01
This second edition systematically leads readers through the process of developing Green's functions for ordinary and partial differential equations. In addition to exploring the classical problems involving the wave, heat, and Helmholtz equations, the book includes special sections on leaky modes, water waves, and absolute/convective instability. The book helps readers develop an intuition about the behavior of Green's functions, and considers the questions of the computational efficiency and possible methods for accelerating the process.
Function, anticipation, representation
Bickhard, Mark. H.
2001-06-01
Function emerges in certain kinds of far-from-equilibrium systems. One important kind of function is that of interactive anticipation, an adaptedness to temporal complexity. Interactive anticipation is the locus of the emergence of normative representational content, and, thus, of representation in general: interactive anticipation is the naturalistic core of the evolution of cognition. Higher forms of such anticipation are involved in the subsequent macro-evolutionary sequence of learning, emotions, and reflexive consciousness.
Energy Technology Data Exchange (ETDEWEB)
McGraw, John T [Placitas, NM; Zimmer, Peter C [Albuquerque, NM; Ackermann, Mark R [Albuquerque, NM
2012-01-24
Methods and apparatus for a structure function monitor provide for generation of parameters characterizing a refractive medium. In an embodiment, a structure function monitor acquires images of a pupil plane and an image plane and, from these images, retrieves the phase over an aperture, unwraps the retrieved phase, and analyzes the unwrapped retrieved phase. In an embodiment, analysis yields atmospheric parameters measured at spatial scales from zero to the diameter of a telescope used to collect light from a source.
LDF (Lag Dependence Functions)
DEFF Research Database (Denmark)
2000-01-01
LDF (Lag Dependence Functions) is an S-PLUS library for identification of non-linear dependencies in univariate time series. The methods can be considered generalizations of the tools applicable for linear time series.......LDF (Lag Dependence Functions) is an S-PLUS library for identification of non-linear dependencies in univariate time series. The methods can be considered generalizations of the tools applicable for linear time series....
Inequalities for Humbert functions
Directory of Open Access Journals (Sweden)
Ayman Shehata
2014-04-01
Full Text Available This paper is motivated by an open problem of Luke’s theorem. We consider the problem of developing a unified point of view on the theory of inequalities of Humbert functions and of their general ratios are obtained. Some particular cases and refinements are given. Finally, we obtain some important results involving inequalities of Bessel and Whittaker’s functions as applications.
Mahamood, Rasheedat Modupe
2017-01-01
This book presents the concept of functionally graded materials as well as their use and different fabrication processes. The authors describe the use of additive manufacturing technology for the production of very complex parts directly from the three dimension computer aided design of the part by adding material layer after layer. A case study is also presented in the book on the experimental analysis of functionally graded material using laser metal deposition process.
Directory of Open Access Journals (Sweden)
W. L. Fouché
1983-03-01
Full Text Available In this article we discuss some aspects of nonlinear functional analysis. It included reviews of Banach’s contraction theorem, Schauder’s fixed point theorem, globalising techniques and applications of homotopy theory to nonlinear functional analysis. The author emphasises that fundamentally new ideas are required in order to achieve a better understanding of phenomena which contain both nonlinear and definite infinite dimensional features.
Purely Functional Structured Programming
Obua, Steven
2010-01-01
The idea of functional programming has played a big role in shaping today's landscape of mainstream programming languages. Another concept that dominates the current programming style is Dijkstra's structured programming. Both concepts have been successfully married, for example in the programming language Scala. This paper proposes how the same can be achieved for structured programming and PURELY functional programming via the notion of LINEAR SCOPE. One advantage of this proposal is that m...
Partly occupied Wannier functions
DEFF Research Database (Denmark)
Thygesen, Kristian Sommer; Hansen, Lars Bruno; Jacobsen, Karsten Wedel
2005-01-01
We introduce a scheme for constructing partly occupied, maximally localized Wannier functions (WFs) for both molecular and periodic systems. Compared to the traditional occupied WFs the partly occupied WFs possess improved symmetry and localization properties achieved through a bonding-antibondin......We introduce a scheme for constructing partly occupied, maximally localized Wannier functions (WFs) for both molecular and periodic systems. Compared to the traditional occupied WFs the partly occupied WFs possess improved symmetry and localization properties achieved through a bonding...
Production Functions Behaving Badly
DEFF Research Database (Denmark)
Fredholm, Thomas
This paper reconsiders Anwar Shaikh's critique of the neoclassical theory of growth and distribution based on its use of aggregate production functions. This is done by reconstructing and extending Franklin M. Fisher's 1971 computer simulations, which Shaikh used to support his critique. Together...... with other recent extensions to Shaikh's seminal work, my results support and strengthen the evidence against the use of aggregate production functions....
Functions & Features of Idioms
Institute of Scientific and Technical Information of China (English)
周来纳
2015-01-01
Idioms, or conventionalized multiword expressions, often but not always non-literal, are hardly marginal in English, though they have been relatively neglected in lexical studies of the language. This neglect is especially evident in respect of the functions of idioms. The aim of this article, accordingly, is to account for the functions of idioms by analyzing what they do with the features of idioms.
Handbook of functional equations functional inequalities
2014-01-01
As Richard Bellman has so elegantly stated at the Second International Conference on General Inequalities (Oberwolfach, 1978), “There are three reasons for the study of inequalities: practical, theoretical, and aesthetic.” On the aesthetic aspects, he said, “As has been pointed out, beauty is in the eye of the beholder. However, it is generally agreed that certain pieces of music, art, or mathematics are beautiful. There is an elegance to inequalities that makes them very attractive.” The content of the Handbook focuses mainly on both old and recent developments on approximate homomorphisms, on a relation between the Hardy–Hilbert and the Gabriel inequality, generalized Hardy–Hilbert type inequalities on multiple weighted Orlicz spaces, half-discrete Hilbert-type inequalities, on affine mappings, on contractive operators, on multiplicative Ostrowski and trapezoid inequalities, Ostrowski type inequalities for the Riemann–Stieltjes integral, means and related functional inequalities, Weighted G...
Directory of Open Access Journals (Sweden)
Parvin Raji
2012-12-01
Full Text Available Background and Aim: All activities of daily living need to balance control in static and dynamic movements. In recent years, a numerous increase can be seen in the functional balance assessment tools. Functional balance tests emphasize on static and dynamic balance, balance in weight transfer, the equilibrium response to the imbalances, and functional mobility. These standardized and available tests assess performance and require minimal or no equipment and short time to run. Functional balance is prerequisite for the most static and dynamic activities in daily life and needs sufficient interaction between sensory and motor systems. According to the critical role of balance in everyday life, and wide application of functional balance tests in the diagnosis and assessment of patients, a review of the functional balance tests was performed.Methods: The Google Scholar, PubMed, Science Direct, Scopus, Magiran, Iran Medex, and IranDoc databases were reviewed and the reliable and valid tests which were mostly used by Iranian researchers were assessed.Conclusion: It seems that Berg balance scale (BBS have been studied by Iranian and foreign researches more than the other tests. This test has high reliability and validity in elderly and in the most neurological disorders.
Functional neuroimaging of sleep.
Nofzinger, Eric A
2005-03-01
Sleep and sleep disorders have traditionally been viewed from a polysomnographic perspective. Although these methods provide information on the timing of various stages of sleep and wakefulness, they do not provide information regarding function in brain structures that have been implicated in the generation of sleep and that may be abnormal in different sleep disorders. Functional neuroimaging methods provide information regarding changes in brain function across the sleep-wake cycle that provides information for models of sleep dysregulation in a variety of sleep disorders. Early studies show reliable increases in function in limbic and anterior paralimbic cortex in rapid eye movement (REM) sleep and decreases in function in higher-order cortical regions in known thalamocortical networks during non-REM sleep. Although most of the early work in this area has been devoted to the study of normal sleep mechanisms, a collection of studies in diverse sleep disorders such as sleep deprivation, depression, insomnia, dyssomnias, narcolepsy, and sleep apnea suggest that functional neuroimaging methods have the potential to clarify the pathophysiology of sleep disorders and to guide treatment strategies.
Directory of Open Access Journals (Sweden)
Pankaj Talwar
2015-01-01
Full Text Available With absolute normal semen analysis parameters it may not be necessary to shift to specialized tests early but in cases with borderline parameters or with history of fertilization failure in past it becomes necessary to do a battery of tests to evaluate different parameters of spermatozoa. Various sperm function tests are proposed and endorsed by different researchers in addition to the routine evaluation of fertility. These tests detect function of a certain part of spermatozoon and give insight on the events in fertilization of the oocyte. The sperms need to get nutrition from the seminal plasma in the form of fructose and citrate (this can be assessed by fructose qualitative and quantitative estimation, citrate estimation. They should be protected from the bad effects of pus cells and reactive oxygen species (ROS (leukocyte detection test, ROS estimation. Their number should be in sufficient in terms of (count, structure normal to be able to fertilize eggs (semen morphology. Sperms should have intact and functioning membrane to survive harsh environment of vagina and uterine fluids (vitality and hypo-osmotic swelling test, should have good mitochondrial function to be able to provide energy (mitochondrial activity index test. They should also have satisfactory acrosome function to be able to burrow a hole in zona pellucida (acrosome intactness test, zona penetration test. Finally, they should have properly packed DNA in the nucleus to be able to transfer the male genes (nuclear chromatic decondensation test to the oocyte during fertilization.
Functional integration over geometries
Mottola, E
1995-01-01
The geometric construction of the functional integral over coset spaces {\\cal M}/{\\cal G} is reviewed. The inner product on the cotangent space of infinitesimal deformations of \\cal M defines an invariant distance and volume form, or functional integration measure on the full configuration space. Then, by a simple change of coordinates parameterizing the gauge fiber \\cal G, the functional measure on the coset space {\\cal M}/{\\cal G} is deduced. This change of integration variables leads to a Jacobian which is entirely equivalent to the Faddeev-Popov determinant of the more traditional gauge fixed approach in non-abelian gauge theory. If the general construction is applied to the case where \\cal G is the group of coordinate reparametrizations of spacetime, the continuum functional integral over geometries, {\\it i.e.} metrics modulo coordinate reparameterizations may be defined. The invariant functional integration measure is used to derive the trace anomaly and effective action for the conformal part of the me...
Space race functional responses.
Sjödin, Henrik; Brännström, Åke; Englund, Göran
2015-02-22
We derive functional responses under the assumption that predators and prey are engaged in a space race in which prey avoid patches with many predators and predators avoid patches with few or no prey. The resulting functional response models have a simple structure and include functions describing how the emigration of prey and predators depend on interspecific densities. As such, they provide a link between dispersal behaviours and community dynamics. The derived functional response is general but is here modelled in accordance with empirically documented emigration responses. We find that the prey emigration response to predators has stabilizing effects similar to that of the DeAngelis-Beddington functional response, and that the predator emigration response to prey has destabilizing effects similar to that of the Holling type II response. A stability criterion describing the net effect of the two emigration responses on a Lotka-Volterra predator-prey system is presented. The winner of the space race (i.e. whether predators or prey are favoured) is determined by the relationship between the slopes of the species' emigration responses. It is predicted that predators win the space race in poor habitats, where predator and prey densities are low, and that prey are more successful in richer habitats.
Directory of Open Access Journals (Sweden)
Samson Z Assefa
2015-08-01
Full Text Available Sleep is a ubiquitous component of animal life including birds and mammals. The exact function of sleep has been one of the mysteries of biology. A considerable number of theories have been put forward to explain the reason(s for the necessity of sleep. To date, while a great deal is known about what happens when animals sleep, there is no definitive comprehensive explanation as to the reason that sleep is an inevitable part of animal functioning. It is well known that sleep is a homeostatically regulated body process, and that prolonged sleep deprivation is fatal in animals. In this paper, we present some of the theories as to the functions of sleep and provide a review of some hypotheses as to the overall physiologic function of sleep. To better understand the purpose for sleeping, we review the effects of sleep deprivation on physical, neurocognitive and psychic function. A better understanding of the purpose for sleeping will be a great advance in our understanding of the nature of the animal kingdom, including our own.
Functional imaging and endoscopy
Institute of Scientific and Technical Information of China (English)
Jian-Guo Zhang; Hai-Feng Liu
2011-01-01
The emergence of endoscopy for the diagnosis of gastrointestinal diseases and the treatment of gastrointestinal diseases has brought great changes.The mere observation of anatomy with the imaging mode using modern endoscopy has played a significant role in this regard.However,increasing numbers of endoscopies have exposed additional deficiencies and defects such as anatomically similar diseases.Endoscopy can be used to examine lesions that are difficult to identify and diagnose.Early disease detection requires that substantive changes in biological function should be observed,but in the absence of marked morphological changes,endoscopic detection and diagnosis are difficult.Disease detection requires not only anatomic but also functional imaging to achieve a comprehensive interpretation and understanding.Therefore,we must ask if endoscopic examination can be integrated with both anatomic imaging and functional imaging.In recent years,as molecular biology and medical imaging technology have further developed,more functional imaging methods have emerged.This paper is a review of the literature related to endoscopic optical imaging methods in the hopes of initiating integration of functional imaging and anatomical imaging to yield a new and more effective type of endoscopy.
Learning View Generalization Functions
Breuel, Thomas M
2007-01-01
Learning object models from views in 3D visual object recognition is usually formulated either as a function approximation problem of a function describing the view-manifold of an object, or as that of learning a class-conditional density. This paper describes an alternative framework for learning in visual object recognition, that of learning the view-generalization function. Using the view-generalization function, an observer can perform Bayes-optimal 3D object recognition given one or more 2D training views directly, without the need for a separate model acquisition step. The paper shows that view generalization functions can be computationally practical by restating two widely-used methods, the eigenspace and linear combination of views approaches, in a view generalization framework. The paper relates the approach to recent methods for object recognition based on non-uniform blurring. The paper presents results both on simulated 3D ``paperclip'' objects and real-world images from the COIL-100 database sho...
Algal functional annotation tool
Energy Technology Data Exchange (ETDEWEB)
Lopez, D. [UCLA; Casero, D. [UCLA; Cokus, S. J. [UCLA; Merchant, S. S. [UCLA; Pellegrini, M. [UCLA
2012-07-01
The Algal Functional Annotation Tool is a web-based comprehensive analysis suite integrating annotation data from several pathway, ontology, and protein family databases. The current version provides annotation for the model alga Chlamydomonas reinhardtii, and in the future will include additional genomes. The site allows users to interpret large gene lists by identifying associated functional terms, and their enrichment. Additionally, expression data for several experimental conditions were compiled and analyzed to provide an expression-based enrichment search. A tool to search for functionally-related genes based on gene expression across these conditions is also provided. Other features include dynamic visualization of genes on KEGG pathway maps and batch gene identifier conversion.
Functional Programming Using F#
DEFF Research Database (Denmark)
Hansen, Michael Reichhardt; Rischel, Hans
This comprehensive introduction to the principles of functional programming using F# shows how to apply basic theoretical concepts to produce succinct and elegant programs. It demonstrates the role of functional programming in a wide spectrum of applications including databases and systems....... Coverage also includes advanced features in the .NET library, the imperative features of F# and topics such as text processing, sequences, computation expressions and asynchronous computation. With a broad spectrum of examples and exercises, the book is perfect for courses in functional programming...... and for self-study. Enhancing its use as a text is an accompanying website with downloadable programs, lecture slides, a mini-projects and links to further F# sources....
Ghrelin and Functional Dyspepsia
Directory of Open Access Journals (Sweden)
Takashi Akamizu
2010-01-01
Full Text Available The majority of patients with dyspepsia have no identifiable cause of their disease, leading to a diagnosis of functional dyspepsia (FD. While a number of different factors affect gut activity, components of the nervous and endocrine systems are essential for normal gut function. Communication between the brain and gut occurs via direct neural connections or endocrine signaling events. Ghrelin, a peptide produced by the stomach, affects gastric motility/emptying and secretion, suggesting it may play a pathophysiological role in FD. It is also possible that the functional abnormalities in FD may affect ghrelin production in the stomach. Plasma ghrelin levels are reported to be altered in FD, correlating with FD symptom score. Furthermore, some patients with FD suffer from anorexia with body-weight loss. As ghrelin increases gastric emptying and promotes feeding, ghrelin therapy may be a new approach to the treatment of FD.
Axler, Sheldon; Ramey, Wade
2013-01-01
This is a book about harmonic functions in Euclidean space. Readers with a background in real and complex analysis at the beginning graduate level will feel comfortable with the material presented here. The authors have taken unusual care to motivate concepts and simplify proofs. Topics include: basic properties of harmonic functions, Poisson integrals, the Kelvin transform, spherical harmonics, harmonic Hardy spaces, harmonic Bergman spaces, the decomposition theorem, Laurent expansions, isolated singularities, and the Dirichlet problem. The new edition contains a completely rewritten chapter on spherical harmonics, a new section on extensions of Bocher's Theorem, new exercises and proofs, as well as revisions throughout to improve the text. A unique software package-designed by the authors and available by e-mail - supplements the text for readers who wish to explore harmonic function theory on a computer.
[Functional mitral regurgitation].
Sade, Leyla Elif
2009-07-01
Functional mitral regurgitation (FMR) is the mitral regurgitation that occurs due to myocardial disease in the presence of normal mitral valve leaflets. This scenario has the different characteristics than the organic mitral regurgitation. Functional mitral regurgitation is a disease of the ventricle and occurs by the deformation of the mitral valve leaflets. This morbid entity is frequent and has bad prognosis. Functional mitral regurgitation is the result of complex pathophysiologic process including left ventricular local and global remodeling, mitral annular and papillary muscle dysfunction, and left ventricular dysfunction. The dynamic behavior of FMR complicates the quantification of the regurgitation. Exercise stress echocardiography is of particular importance in the evaluation of the hemodynamic burden of FMR. Particular pathophysiological properties of the FMR necessitate different therapeutic approaches than the current ones for classical mitral regurgitation.
DEFF Research Database (Denmark)
Nielsen, Line A.; Zois, Nora Elisabeth; Pedersen, Henrik D.
2007-01-01
Background: Clinical studies investigating platelet function in dogs have had conflicting results that may be caused by normal physiologic variation in platelet response to agonists. Objectives: The objective of this study was to investigate platelet function in clinically healthy dogs of 4...... different breeds by whole-blood aggregometry and with a point-of-care platelet function analyzer (PFA-100), and to evaluate the effect of acetylsalicylic acid (ASA) administration on the results from both methods. Methods: Forty-five clinically healthy dogs (12 Cavalier King Charles Spaniels [CKCS], 12...... applied. However, the importance of these breed differences remains to be investigated. The PFA-100 method with Col + Epi as agonists, and ADP-induced platelet aggregation appear to be sensitive to ASA in dogs....
Protein Functionalized Nanodiamond Arrays
Directory of Open Access Journals (Sweden)
Liu YL
2010-01-01
Full Text Available Abstract Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.
Quantal density functional theory
Sahni, Viraht
2016-01-01
This book deals with quantal density functional theory (QDFT) which is a time-dependent local effective potential theory of the electronic structure of matter. The treated time-independent QDFT constitutes a special case. In the 2nd edition, the theory is extended to include the presence of external magnetostatic fields. The theory is a description of matter based on the ‘quantal Newtonian’ first and second laws which is in terms of “classical” fields that pervade all space, and their quantal sources. The fields, which are explicitly defined, are separately representative of electron correlations due to the Pauli exclusion principle, Coulomb repulsion, correlation-kinetic, correlation-current-density, and correlation-magnetic effects. The book further describes Schrödinger theory from the new physical perspective of fields and quantal sources. It also describes traditional Hohenberg-Kohn-Sham DFT, and explains via QDFT the physics underlying the various energy functionals and functional derivatives o...
Spaces of continuous functions
Groenewegen, G L M
2016-01-01
The space C(X) of all continuous functions on a compact space X carries the structure of a normed vector space, an algebra and a lattice. On the one hand we study the relations between these structures and the topology of X, on the other hand we discuss a number of classical results according to which an algebra or a vector lattice can be represented as a C(X). Various applications of these theorems are given. Some attention is devoted to related theorems, e.g. the Stone Theorem for Boolean algebras and the Riesz Representation Theorem. The book is functional analytic in character. It does not presuppose much knowledge of functional analysis; it contains introductions into subjects such as the weak topology, vector lattices and (some) integration theory.
Generating functions for symmetric and shifted symmetric functions
Jing, Naihuan; Rozhkovskaya, Natasha
2016-01-01
We describe generating functions for several important families of classical symmetric functions and shifted Schur functions. The approach is originated from vertex operator realization of symmetric functions and offers a unified method to treat various families of symmetric functions and their shifted analogues.
Clocks and cardiovascular function
McLoughlin, Sarah C.; Haines, Philip; FitzGerald, Garret A.
2016-01-01
Circadian clocks in central and peripheral tissues enable the temporal synchronization and organization of molecular and physiological processes of rhythmic animals, allowing optimum functioning of cells and organisms at the most appropriate time of day. Disruption of circadian rhythms, from external or internal forces, leads to widespread biological disruption and is postulated to underlie many human conditions, such as the incidence and timing of cardiovascular disease. Here, we describe in vivo and in vitro methodology relevant to studying the role of circadian rhythms in cardiovascular function and dysfunction PMID:25707279
Lieber, Michael
1989-06-01
It is something of a miracle that the nonrelativistic Schrodinger equation with a Coulomb potential can be solved for the wavefunction in exact analytic form. Even more miraculous is the result of Schwinger which enables the Green's function to be solved in closed form, for this is in effect, an infinite sum of wavefunction products. In the relativistic case too the wavefunction can be found in closed form, but as yet no such result for the Green's function has been found. This lecture provides a brief overview of the situation with an emphasis on the ``hidden symmetry'' which underlies the nonrelativisitic problem and its degenerate form which carries over to the relativistic case.
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
@@ Genomics is a biology term appeared ten years ago, used to describe the researches of genomic mapping, sequencing, and structure analysis, etc. Genomics, the first journal for publishing papers on genomics research was born in 1986. In the past decade, the concept of genomics has been widely accepted by scientists who are engaging in biology research. Meanwhile, the research scope of genomics has been extended continuously, from simple gene mapping and sequencing to function genomics study. To reflect the change, genomics is divided into two parts now, the structure genomics and the function genomics.
Rarefied elliptic hypergeometric functions
Spiridonov, V P
2016-01-01
We prove exact evaluation formulae for two multiple rarefied elliptic beta integrals related to the simplest lens space. These integrals generalize the multiple type I and II van Diejen-Spiridonov integrals attached to the root system $C_n$. Symmetries of the rarefied elliptic analogue of the Euler-Gauss hypergeometric function are described and the corresponding generalization of the hypergeometric equation is constructed. An extension of the latter function to the root system $C_n$ and applications to some eigenvalue problems are briefly discussed.
Magnetosome production and functionalization
DEFF Research Database (Denmark)
Anyaogu, Diana Chinyere; Zhuang, Shiwen; Mortensen, Uffe Hasbro
as a model organism used to produce magnetosmes and is known to require a low dissolved oxygen (DO) concentration and iron during cultivation for magnetosome production. However, the relationship between these parameters and fermentation behavior is not well understood. We will present a study where we...... investigate how the addition of iron impacts the physiology of the MSR-1 cells and the expression of key genes involved in the production of mangetosomes. Furthermore, utilization of magnetosomes for applications as immunoassays requires the functionalization of the magnetsomes. Functionalization...
Sarason, Donald
2007-01-01
Complex Function Theory is a concise and rigorous introduction to the theory of functions of a complex variable. Written in a classical style, it is in the spirit of the books by Ahlfors and by Saks and Zygmund. Being designed for a one-semester course, it is much shorter than many of the standard texts. Sarason covers the basic material through Cauchy's theorem and applications, plus the Riemann mapping theorem. It is suitable for either an introductory graduate course or an undergraduate course for students with adequate preparation. The first edition was published with the title Notes on Co
A stabilized pairing functional
Erler, J; Reinhard, P --G
2008-01-01
We propose a modified pairing functional for nuclear structure calculations which avoids the abrupt phase transition between pairing and non-pairing states. The intended application is the description of nuclear collective motion where the smoothing of the transition is compulsory to remove singularities. The stabilized pairing functional allows a thoroughly variational formulation, unlike the Lipkin-Nogami (LN) scheme which is often used for the purpose of smoothing. First applications to nuclear ground states and collective excitations prove the reliability and efficiency of the proposed stabilized pairing.
Chromatin Structure and Function
Wolffe, Alan P
1999-01-01
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active
GADRAS Detector Response Function.
Energy Technology Data Exchange (ETDEWEB)
Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.
2014-11-01
The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.
Stability of Trigonometric Functional Equations in Generalized Functions
Directory of Open Access Journals (Sweden)
Jeongwook Chang
2010-01-01
Full Text Available We consider the Hyers-Ulam stability of a class of trigonometric functional equations in the spaces of generalized functions such as Schwartz distributions, Fourier hyperfunctions, and Gelfand generalized functions.
Executive functions in synesthesia
R. Rouw; J. van Driel; K. Knip; K.R. Ridderinkhof
2013-01-01
In grapheme-color synesthesia, a number or letter can evoke two different and possibly conflicting (real and synesthetic) color sensations at the same time. In this study, we investigate the relationship between synesthesia and executive control functions. First, no general skill differences were ob
Objectification and Semiotic Function
Santi, George
2011-01-01
The objective of this paper is to study students' difficulties when they have to ascribe the same meaning to different representations of the same mathematical object. We address two theoretical tools that are at the core of Radford's cultural semiotic and Godino's onto-semiotic approaches: objectification and the semiotic function. The analysis…
Choice probability generating functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel; Bierlaire, Michel
2013-01-01
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice prob...
Educational Production Functions.
Polachek, Solomon W.; And Others
1978-01-01
A constant partial elasticity of substitution production function for academic achievement is presented and estimated with nonlinear maximum likelihood methods. We find that ability and time devoted to various aspects of the learning process are the most important determinants of students' accomplishments. (Author/CTM)
functional-differential inequalities
Directory of Open Access Journals (Sweden)
Ludwik Byszewski
1995-01-01
Full Text Available A theorem about a system of strong impulsive degenerate nonlinear parabolic functional-differential inequalities in an arbitrary parabolic set is proved. As a consequence of the theorem, some theorems about impulsive degenerate nonlinear parabolic differential inequalities and the uniqueness of a classical solution of an impulsive degenerate nonlinear parabolic differential problem are established.
Thrombocyte and thrombocyte function
Institute of Scientific and Technical Information of China (English)
1997-01-01
970384 The mechanism of preserving platelet func-tion by aprotinin during cardiopulmonary bypass.YANG Tianyu(杨天宇), et al. Anesthesiol &Cardiòpulmon Bypass Lab, Cardiovasc Instit & FuwaiHosp, CAMS & PUMC, Beijing, 100037. Chin Cir J1996; 11(12): 739-742.
Directory of Open Access Journals (Sweden)
Ramesh Kalindri
2014-06-01
Full Text Available Currently, software engineers are increasingly turning to the option of automating functional tests, but not always have successful in this endeavor. Reasons range from low planning until over cost in the process. Some principles that can guide teams in automating these tests are described in this article.
Hantush Well Function Revisited
Veling, E.J.M.; Maas, C.
2010-01-01
In this paper we comment on some recent numerical and analytical work to evaluate the Hantush Well Function. We correct an expression found in a Comment by Nadarajah (J. of Hydrology, vol. 338, p. 152-153 (2007)) to a paper by Prodanoff et al. (J. of Hydrology, vol. 318, p. 173-183 (2006)). We subse
Brants, T; Krenn, B; Brants, Thorsten; Skut, Wojciech; Krenn, Brigitte
1997-01-01
This paper addresses issues in automated treebank construction. We show how standard part-of-speech tagging techniques extend to the more general problem of structural annotation, especially for determining grammatical functions and syntactic categories. Annotation is viewed as an interactive process where manual and automatic processing alternate. Efficiency and accuracy results are presented. We also discuss further automation steps.
Functional ingredients from microalgae
Buono, S.; Langellotti, A.L.; Martello, A.; Rinna, F.; Fogliano, V.
2014-01-01
A wide variety of natural sources are under investigation to evaluate their possible use for new functional ingredient formulation. Some records attested the traditional and ancient use of wild harvested microalgae as human food but their cultivation for different purposes started about 40 years ago
Laboratory Density Functionals
Giraud, B G
2007-01-01
We compare several definitions of the density of a self-bound system, such as a nucleus, in relation with its center-of-mass zero-point motion. A trivial deconvolution relates the internal density to the density defined in the laboratory frame. This result is useful for the practical definition of density functionals.
Empirical microeconomics action functionals
Baaquie, Belal E.; Du, Xin; Tanputraman, Winson
2015-06-01
A statistical generalization of microeconomics has been made in Baaquie (2013), where the market price of every traded commodity, at each instant of time, is considered to be an independent random variable. The dynamics of commodity market prices is modeled by an action functional-and the focus of this paper is to empirically determine the action functionals for different commodities. The correlation functions of the model are defined using a Feynman path integral. The model is calibrated using the unequal time correlation of the market commodity prices as well as their cubic and quartic moments using a perturbation expansion. The consistency of the perturbation expansion is verified by a numerical evaluation of the path integral. Nine commodities drawn from the energy, metal and grain sectors are studied and their market behavior is described by the model to an accuracy of over 90% using only six parameters. The paper empirically establishes the existence of the action functional for commodity prices that was postulated to exist in Baaquie (2013).
Deimling, Klaus
1985-01-01
topics. However, only a modest preliminary knowledge is needed. In the first chapter, where we introduce an important topological concept, the so-called topological degree for continuous maps from subsets ofRn into Rn, you need not know anything about functional analysis. Starting with Chapter 2, where infinite dimensions first appear, one should be familiar with the essential step of consider ing a sequence or a function of some sort as a point in the corresponding vector space of all such sequences or functions, whenever this abstraction is worthwhile. One should also work out the things which are proved in § 7 and accept certain basic principles of linear functional analysis quoted there for easier references, until they are applied in later chapters. In other words, even the 'completely linear' sections which we have included for your convenience serve only as a vehicle for progress in nonlinearity. Another point that makes the text introductory is the use of an essentially uniform mathematical languag...
Holographic Three point Functions
DEFF Research Database (Denmark)
Martirosyan, Ara
The main subject of this thesis is the computation of structure constants appearing in the three-point functions for certain type of states/operators in the context of the AdS/CFT correspondence, which is one of the important parts of the dynamical problem in the dual theories of the correspondence...
Choice Probability Generating Functions
DEFF Research Database (Denmark)
Fosgerau, Mogens; McFadden, Daniel L; Bierlaire, Michel
This paper considers discrete choice, with choice probabilities coming from maximization of preferences from a random utility field perturbed by additive location shifters (ARUM). Any ARUM can be characterized by a choice-probability generating function (CPGF) whose gradient gives the choice...
Enzyme design: Functional Frankensteins
Makhlynets, Olga V.; Korendovych, Ivan V.
2016-09-01
An artificial esterase with no known natural structural analogues has been formed via the homo-heptameric self-assembly of a designed peptide. This esterase represents the first report of a functional catalytic triad rationally engineered into a de novo protein framework.
Bayes Multiple Decision Functions
Wu, Wensong
2011-01-01
This paper deals with the problem of simultaneously making many (M) binary decisions based on one realization of a random data matrix X. M is typically large and X will usually have M rows associated with each of the M decisions to make, but for each row the data may be low dimensional. A Bayesian decision-theoretic approach for this problem is implemented with the overall loss function being a cost-weighted linear combination of Type I and Type II loss functions. The class of loss functions considered allows for the use of the false discovery rate (FDR), false nondiscovery rate (FNR), and missed discovery rate (MDR) in assessing the decision. Through this Bayesian paradigm, the Bayes multiple decision function (BMDF) is derived and an efficient algorithm to obtain the optimal Bayes action is described. In contrast to many works in the literature where the rows of the matrix X are assumed to be stochastically independent, we allow in this paper a dependent data structure with the associations obtained through...
Automatic Functional Harmonic Analysis
de Haas, W.B.; Magalhães, J.P.; Wiering, F.; Veltkamp, R.C.
2013-01-01
Music scholars have been studying tonal harmony intensively for centuries, yielding numerous theories and models. Unfortunately, a large number of these theories are formulated in a rather informal fashion and lack mathematical precision. In this article we present HarmTrace, a functional model of W
Predicatively computable functions on sets
Arai, Toshiyasu
2012-01-01
Inspired from a joint work by A. Beckmann, S. Buss and S. Friedman, we propose a class of set-theoretic functions, predicatively computable functions. Each function in this class is polynomial time computable when we restrict to finite binary strings. Moreover a fragment of set theory is given in which \\Sigma_1-definable functions are exactly the functions in the class.
Completely monotonic functions related to logarithmic derivatives of entire functions
DEFF Research Database (Denmark)
Pedersen, Henrik Laurberg
2011-01-01
The logarithmic derivative l(x) of an entire function of genus p and having only non-positive zeros is represented in terms of a Stieltjes function. As a consequence, (-1)p(xml(x))(m+p) is a completely monotonic function for all m ≥ 0. This generalizes earlier results on complete monotonicity...... of functions related to Euler's psi-function. Applications to Barnes' multiple gamma functions are given....
EXECUTIVE FUNCTIONING IN SCHIZOPHRENIA
Directory of Open Access Journals (Sweden)
Gricel eOrellana
2013-06-01
Full Text Available The executive function (EF is a set of abilities, which allows us to invoke voluntary control of our behavioral responses. These functions enable human beings to develop and carry out plans, make up analogies, obey social rules, solve problems, adapt to unexpected circumstances, do many tasks simultaneously and locate episodes in time and place. EF includes divided attention and sustained attention, working memory, set-shifting, flexibility, planning and the regulation of goal directed behavior and can be defined as a brain function underlying the human faculty to act or think not only in reaction to external events but also in relation with internal goals and states. EF is mostly associated with dorsolateral prefrontal cortex (PFC. Besides EF, PFC is involved in self-regulation of behavior, i.e. the ability to regulate behavior according to internal goals and constraints, particularly in less structured situations. Self-regulation of behavior is subtended by ventral medial /orbital PFC. Impairment of EF is one of the most commonly observed deficits in schizophrenia through the various disease stages. Impairment in tasks measuring conceptualization, planning, cognitive flexibility, verbal fluency, ability to solve complex problems and working memory occur in schizophrenia. Disorders detected by executive tests are consistent with evidence from functional neuroimaging, which have shown PFC dysfunction in patients while performing these kinds of tasks. Schizophrenics also exhibit deficit in odor identifying, decision-making and self-regulation of behavior suggesting dysfunction of the orbital PFC. However, impairment in executive tests is explained by dysfunction of prefronto-striato-thalamic, prefronto-parietal and prefronto-temporal neural networks mainly. Disorders in executive functions may be considered central facts with respect to schizophrenia and it has been suggested that negative symptoms may be explained by that executive dysfunction.
Partition density functional theory
Nafziger, Jonathan
Partition density functional theory (PDFT) is a method for dividing a molecular electronic structure calculation into fragment calculations. The molecular density and energy corresponding to Kohn Sham density-functional theory (KS-DFT) may be exactly recovered from these fragments. Each fragment acts as an isolated system except for the influence of a global one-body 'partition' potential which deforms the fragment densities. In this work, the developments of PDFT are put into the context of other fragment-based density functional methods. We developed three numerical implementations of PDFT: One within the NWChem computational chemistry package using basis sets, and the other two developed from scratch using real-space grids. It is shown that all three of these programs can exactly reproduce a KS-DFT calculation via fragment calculations. The first of our in-house codes handles non-interacting electrons in arbitrary one-dimensional potentials with any number of fragments. This code is used to explore how the exact partition potential changes for different partitionings of the same system and also to study features which determine which systems yield non-integer PDFT occupations and which systems are locked into integer PDFT occupations. The second in-house code, CADMium, performs real-space calculations of diatomic molecules. Features of the exact partition potential are studied for a variety of cases and an analytical formula determining singularities in the partition potential is derived. We introduce an approximation for the non-additive kinetic energy and show how this quantity can be computed exactly. Finally a PDFT functional is developed to address the issues of static correlation and delocalization errors in approximations within DFT. The functional is applied to the dissociation of H2 + and H2.
THE WAVELET TRANSFORM OF PERIODIC FUNCTION AND NONSTATIONARY PERIODIC FUNCTION
Institute of Scientific and Technical Information of China (English)
刘海峰; 周炜星; 王辅臣; 龚欣; 于遵宏
2002-01-01
Some properties of the wavelet transform of trigonometric function, periodic function and nonstationary periodic function have been investigated. The results show that the peak height and width in wavelet energy spectrum of a periodic function are in proportion to its period. At the same time, a new equation, which can truly reconstruct a trigonometric function with only one scale wavelet coefficient, is presented. The reconstructed wave shape of a periodic function with the equation is better than any term of its Fourier series. And the reconstructed wave shape of a class of nonstationary periodic function with this equation agrees well with the function.
Uniqueness property for quasiharmonic functions
Directory of Open Access Journals (Sweden)
Sevdiyor A. Imomkulov
2014-10-01
Full Text Available In this paper we consider a class of continuous functions, called quasiaharmonic functions, admitting best approximations by harmonic polynomials. In this class we prove a uniqueness theorem by analogy with the analytic functions.
Functional magnetic microspheres
Yen, Shiao-Ping S. (Inventor); Rembaum, Alan (Inventor); Landel, Robert F. (Inventor)
1981-01-01
Functional magnetic particles are formed by dissolving a mucopolysaccharide such as chitosan in acidified aqueous solution containing a mixture of ferrous chloride and ferric chloride. As the pH of the solution is raised magnetite is formed in situ in the solution by raising the pH. The dissolved chitosan is a polyelectrolyte and forms micelles surrounding the granules at pH of 8-9. The chitosan precipitates on the granules to form microspheres containing the magnetic granules. On addition of the microspheres to waste aqueous streams containing dissolved ions, the hydroxyl and amine functionality of the chitosan forms chelates binding heavy metal cations such as lead, copper, and mercury and the chelates in turn bind anions such as nitrate, fluoride, phosphate and borate.
Functional Biomimetic Architectures
Levine, Paul M.
N-substituted glycine oligomers, or 'peptoids,' are a class of sequence--specific foldamers composed of tertiary amide linkages, engendering proteolytic stability and enhanced cellular permeability. Peptoids are notable for their facile synthesis, sequence diversity, and ability to fold into distinct secondary structures. In an effort to establish new functional peptoid architectures, we utilize the copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC) reaction to generate peptidomimetic assemblies bearing bioactive ligands that specifically target and modulate Androgen Receptor (AR) activity, a major therapeutic target for prostate cancer. Additionally, we explore chemical ligation protocols to generate semi-synthetic hybrid biomacromolecules capable of exhibiting novel structures and functions not accessible to fully biosynthesized proteins.
Functionalization of Carbon Nanotubes
Khare, Bishun N. (Inventor); Meyyappan, Meyya (Inventor)
2009-01-01
Method and system for functionalizing a collection of carbon nanotubes (CNTs). A selected precursor gas (e.g., H2 or F2 or CnHm) is irradiated to provide a cold plasma of selected target species particles, such as atomic H or F, in a first chamber. The target species particles are d irected toward an array of CNTs located in a second chamber while suppressing transport of ultraviolet radiation to the second chamber. A CNT array is functionalized with the target species particles, at or below room temperature, to a point of saturation, in an exposure time interval no longer than about 30 sec. *Discrimination against non-target species is provided by (i) use of a target species having a lifetime that is much greater than a lifetime of a non-target species and/or (2) use of an applied magnetic field to discriminate between charged particle trajectories for target species and for non-target species.
Vestnorden. A functional region?
Directory of Open Access Journals (Sweden)
Grétar Þór Eyþórsson
2013-06-01
Full Text Available This article discusses the issue of what kind of a region Vestnorden is. The need for such a discussion arises from the challenges posed by globalisation for the idea and construction of the West Nordic space, and the need to observe how this regional unit counters these processes. The article is based on an analytical framework which presupposes that a functional region has to consist of four elements. First, whether the space has its own institutions for decision making; second, how far there is economic complementarities among the involved nations and territories; third, to what degree they have common economic interests; and finally, to what extent social, cultural and historical ties exist between the territories involved. The article argues that there is an urgent need to discuss and reorient the institutional functionality of Vestnorden as a regional unit.
DEFF Research Database (Denmark)
Bech-Larsen, Tino; Scholderer, Joachim
2007-01-01
reading of the main principles of the harmonized regulation COM/2003/0424, this situation is about to change. This article reviews the regulatory aspects, the results of consumer research and the marketing strategies regarding the use of health claims for functional foods in Europe, and it comments......The fact that the European markets for functional foods generally are less developed, compared to the US and the Japanese markets, has often been attributed to a restrictive and inconsistent health claim legislation in and between the European countries. With the European Parliament's second...... on the lack of correspondence between the new regulation and the marketing experiences and research as regard consumer reactions to health claims....
Directory of Open Access Journals (Sweden)
VEZURE OANA SABINA
2011-09-01
Full Text Available The emergence of public finances is due to objective causes needs and determined their main function being to obtain the financial resources it needs for the State to exercise its powers and on the way to intervene in the economy and society general. Public finances are necessary, subjectively and objectively, as it contributes to accomplishing the tasks and functions of the state, which could not be realized without financial leverage. Public finances are inextricably linked to the existence of the state, and public sector's role in the economy. Thus, they express "social relations, economic arising in the establishment and use of public funds between the state, on the one hand, and members of society on the other hand, to meet the needs of general interest of society" [1]. Thus, the role of public finance is to meet the needs of general interest or collective needs.
Subtypes of functional dyspepsia
Institute of Scientific and Technical Information of China (English)
Georgina Baker; Robert J Fraser; Graeme Young
2006-01-01
Functional dyspepsia is a common clinical condition characterised by chronic or recurrent upper abdominal pain or discomfort commonly associated with a variety of associated gastrointestinal symptoms and a normal endoscopy. To standardise research-based approaches,an initial categorisation of into sub groups was agreed to, based on clusters of symptoms. However the early expectation that these subgroups would be associated with distinct pathophysiologies amenable to specific therapy has not been realised. A classification based on the most troublesome symptom has been suggested but the utility of this is also unclear. More recent data suggest that some of the pathophysiologic dysfunctions may be associated with specific symptoms and so provide a better tool for grouping patients. But this approach remains incomplete as current insights into the pathogenesis are still too limited for this to be satisfactory. In conclusion, no classification provides for an adequate treatment-based approach to the syndrome of functional dyspepsia. As a consequence treatment remains largely empiric.
DEFF Research Database (Denmark)
2016-01-01
Renowned experts present the latest knowledge Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since...... the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information...... on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin...
Nuclear Parton Distribution Functions
Energy Technology Data Exchange (ETDEWEB)
I. Schienbein, J.Y. Yu, C. Keppel, J.G. Morfin, F. Olness, J.F. Owens
2009-06-01
We study nuclear effects of charged current deep inelastic neutrino-iron scattering in the framework of a {chi}{sup 2} analysis of parton distribution functions (PDFs). We extract a set of iron PDFs which are used to compute x{sub Bj}-dependent and Q{sup 2}-dependent nuclear correction factors for iron structure functions which are required in global analyses of free nucleon PDFs. We compare our results with nuclear correction factors from neutrino-nucleus scattering models and correction factors for charged-lepton--iron scattering. We find that, except for very high x{sub Bj}, our correction factors differ in both shape and magnitude from the correction factors of the models and charged-lepton scattering.
DEFF Research Database (Denmark)
Larsen, S H; Wagner, G; Heitmann, B L
2007-01-01
OBJECTIVE: To review the literature on the relationship between obesity and sexual function. METHOD: A search in the medical literature from 1966 and onwards was carried out through Medline and Embase for publications on obesity, in combination with Medical Subject Heading words related to sexual...... function and dysfunction. COMMENTS: Four prospective and seven cross-sectional studies were found describing association between obesity and erectile dysfunction (ED). One cross-sectional study was found describing obesity and female sexual dysfunction (FSD). The prospective studies on ED all demonstrated...... activity among both men and women after weight loss intervention. CONCLUSION: Support for the assumption that obesity is associated with ED was found in both prospective and cross-sectional studies. FSD was not adequately described in the literature and prospective studies are needed here. Results from...
Physically Functional Materials
Berg, Rolf Henrik; Hvilsted, Søren; Ramanujam, P.S.
2002-01-01
The invention relates to novel monodisperse or polydisperse compounds, in general named DNO (diamino acid Nalpha-substituted oligopeptides), preferably low molecular weight polypeptides, e.g., based on ornithine, lysine, diaminobutyric acid, diaminopropionic acid, aminoethylglycine or other amino acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techn...
Haque, S Shajidul
2016-01-01
We propose a simple and generic holographic $c$-function that is defined purely from geometry by using the non-affine expansion for null congruences. We examined the proposal for BPS black solutions in $\\mathcal{N}=2$ gauged supergravity that interpolate between two different dimensional AdS spacetimes and also for domain wall solutions. Moreover, we commented on the relation of this geometric proposal with the one from the holographic entanglement entropy.
Generalised twisted partition functions
Petkova, V B
2001-01-01
We consider the set of partition functions that result from the insertion of twist operators compatible with conformal invariance in a given 2D Conformal Field Theory (CFT). A consistency equation, which gives a classification of twists, is written and solved in particular cases. This generalises old results on twisted torus boundary conditions, gives a physical interpretation of Ocneanu's algebraic construction, and might offer a new route to the study of properties of CFT.
Design of Functional Metalloproteins
Lu, Yi; Yeung, Natasha; Sieracki, Nathan; Marshall, Nicholas M.
2009-01-01
Metalloproteins catalyze some of the most difficult and yet important functions in Nature, such as photosynthesis and water oxidation. An ultimate test of our knowledge of how metalloproteins work is by designing novel metalloproteins. Such design can not only reveal hidden structural features that may be missing from studies of native metalloproteins and their variants, but also result in new metalloenzymes for biotechnological and pharmaceutical applications. While it is much more challengi...
Which impulse response function?
2011-01-01
This paper compares standard and local projection techniques in the production of impulse response functions both theoretically and empirically. Through careful selection of a structural decomposition, the comparison continues to an application of US data to the textbook ISLM model. It is argued that local projection techniques offer a remedy to the bias of the conventional method especially at horizons longer than the vector autoregression's lag length. The application highlights that the te...
Analyzing Pseudophosphatase Function.
Hinton, Shantá D
2016-01-01
Pseudophosphatases regulate signal transduction cascades, but their mechanisms of action remain enigmatic. Reflecting this mystery, the prototypical pseudophosphatase STYX (phospho-serine-threonine/tyrosine-binding protein) was named with allusion to the river of the dead in Greek mythology to emphasize that these molecules are "dead" phosphatases. Although proteins with STYX domains do not catalyze dephosphorylation, this in no way precludes their having other functions as integral elements of signaling networks. Thus, understanding their roles in signaling pathways may mark them as potential novel drug targets. This chapter outlines common strategies used to characterize the functions of pseudophosphatases, using as an example MK-STYX [mitogen-activated protein kinase (MAPK) phospho-serine-threonine/tyrosine binding], which has been linked to tumorigenesis, apoptosis, and neuronal differentiation. We start with the importance of "restoring" (when possible) phosphatase activity in a pseudophosphatase so that the active mutant may be used as a comparison control throughout immunoprecipitation and mass spectrometry analyses. To this end, we provide protocols for site-directed mutagenesis, mammalian cell transfection, co-immunoprecipitation, phosphatase activity assays, and immunoblotting that we have used to investigate MK-STYX and the active mutant MK-STYXactive. We also highlight the importance of utilizing RNA interference (RNAi) "knockdown" technology to determine a cellular phenotype in various cell lines. Therefore, we outline our protocols for introducing short hairpin RNA (shRNA) expression plasmids into mammalians cells and quantifying knockdown of gene expression with real-time quantitative PCR (qPCR). A combination of cellular, molecular, biochemical, and proteomic techniques has served as powerful tools in identifying novel functions of the pseudophosphatase MK-STYX. Likewise, the information provided here should be a helpful guide to elucidating the
LENUS (Irish Health Repository)
Lang, E E
2010-06-01
Vestibular symptoms of vertigo, dizziness and dysequilibrium are common complaints which can be disabling both physically and psychologically. Routine examination of the ear nose and throat and neurological system are often normal in these patients. An accurate history and thorough clinical examination can provide a diagnosis in the majority of patients. However, in a subgroup of patients, vestibular function testing may be invaluable in arriving at a correct diagnosis and ultimately in the optimal treatment of these patients.
Heart function and hemodynamics
Institute of Scientific and Technical Information of China (English)
1993-01-01
930054 Clinical assessment of left ventricularfunction by equilibrium radionuclide ventriculo-graphy before and after mitral valve replace-ment.CHU Yinping(褚银平),et al.2nd Hosp,Shanxi Med Coll,Taiyuan.Chin Cir J 1992;7(5):457-458.Equilibrium radionuclide ventriculographywas used to estimate the left ventricular(LV)function in control subjects(Group 1;n=8)and in 24 patients of mitral valvular diseasesChina Medical Abstracts(Internal Medicine)
Oden, J Tinsley
2010-01-01
The textbook is designed to drive a crash course for beginning graduate students majoring in something besides mathematics, introducing mathematical foundations that lead to classical results in functional analysis. More specifically, Oden and Demkowicz want to prepare students to learn the variational theory of partial differential equations, distributions, and Sobolev spaces and numerical analysis with an emphasis on finite element methods. The 1996 first edition has been used in a rather intensive two-semester course. -Book News, June 2010
Notes on the ellipsoidal function
Liang, Chang-Hong
2017-01-01
This book focuses on the ellipsoidal function, which serves as an evolution and extension of the circular function (trigonometric function) and elliptic function. It presents an in-depth discussion of the ellipsoidal function (algebra) theory and the conformal mapping (geometry) theory of the ellipsoid function, demonstrating the outstanding performance of the ellipsoid function response filter. Applications of the ellipsoidal function include the capacitance of ellipsoidal conductors and the surface area of ellipsoids, which in turn correspond to ellipsoidal integrals of the first kind and the second kind, respectively. The book offers a valuable reference guide for undergraduates, graduate students and researchers in the related fields. .
Remarks on Shintani's zeta function
Wakayama, Masato
2005-01-01
We introduce a zeta function attached to a representation of a group. We show that the multi-dimensional zeta function due to Shintani [Sh 1], which is a generalization of the multiple Hurwitz zeta function, can be obtained in this framework. We also construct a gamma function from the zeta function attached to a representation via zeta regularization. We study then a $q$-analogue of the Shintani zeta function and the corresponding gamma function. A sine function defined via the reflection fo...
Posttraumatic functional movement disorders.
Ganos, C; Edwards, M J; Bhatia, K P
2017-01-01
Traumatic injury to the nervous system may account for a range of neurologic symptoms. Trauma location and severity are important determinants of the resulting symptoms. In severe head injury with structural brain abnormalities, the occurrence of trauma-induced movement disorders, most commonly hyperkinesias such as tremor and dystonia, is well recognized and its diagnosis straightforward. However, the association of minor traumatic events, which do not lead to significant persistent structural brain damage, with the onset of movement disorders is more contentious. The lack of clear clinical-neuroanatomic (or symptom lesion) correlations in these cases, the variable timing between traumatic event and symptom onset, but also the presence of unusual clinical features in a number of such patients, which overlap with signs encountered in patients with functional neurologic disorders, contribute to this controversy. The purpose of this chapter is to provide an overview of the movement disorders, most notably dystonia, that have been associated with peripheral trauma and focus on their unusual characteristics, as well as their overlap with functional neurologic disorders. We will then provide details on pathophysiologic views that relate minor peripheral injuries to the development of movement disorders and compare them to knowledge from primary organic and functional movement disorders. Finally, we will comment on the appropriate management of these disorders.
Functions of multivector variables.
Chappell, James M; Iqbal, Azhar; Gunn, Lachlan J; Abbott, Derek
2015-01-01
As is well known, the common elementary functions defined over the real numbers can be generalized to act not only over the complex number field but also over the skew (non-commuting) field of the quaternions. In this paper, we detail a number of elementary functions extended to act over the skew field of Clifford multivectors, in both two and three dimensions. Complex numbers, quaternions and Cartesian vectors can be described by the various components within a Clifford multivector and from our results we are able to demonstrate new inter-relationships between these algebraic systems. One key relationship that we discover is that a complex number raised to a vector power produces a quaternion thus combining these systems within a single equation. We also find a single formula that produces the square root, amplitude and inverse of a multivector over one, two and three dimensions. Finally, comparing the functions over different dimension we observe that Cl(R(3)) provides a particularly versatile algebraic framework.
Functions of multivector variables.
Directory of Open Access Journals (Sweden)
James M Chappell
Full Text Available As is well known, the common elementary functions defined over the real numbers can be generalized to act not only over the complex number field but also over the skew (non-commuting field of the quaternions. In this paper, we detail a number of elementary functions extended to act over the skew field of Clifford multivectors, in both two and three dimensions. Complex numbers, quaternions and Cartesian vectors can be described by the various components within a Clifford multivector and from our results we are able to demonstrate new inter-relationships between these algebraic systems. One key relationship that we discover is that a complex number raised to a vector power produces a quaternion thus combining these systems within a single equation. We also find a single formula that produces the square root, amplitude and inverse of a multivector over one, two and three dimensions. Finally, comparing the functions over different dimension we observe that Cl(R(3 provides a particularly versatile algebraic framework.
[Functional hypothalamic amenorrhea].
Stárka, Luboslav; Dušková, Michaela
2015-10-01
Functional hypothalamic amenorrhea (FHA) besides pregnancy and syndrome of polycystic ovary is one of the most common causes of secondary amenorrhea. FHA results from the aberrations in pulsatile gonadotropin-releasing hormone (GnRH) secretion, which in turn causes impairment of the gonadotropins (follicle-stimulating hormone and luteinizing hormone). FHA is a form of the defence of organism in situations where life functions are more important than reproductive function. FHA is reversible; it can be normalized after ceasing the stress situation. There are three types of FHA: weight loss related, stress-related, and exercise-related amenorrhea. The final consequences are complex hormonal changes manifested by profound hypoestrogenism. Additionally, these patients present mild hypercortisolemia, low serum insulin levels, low insulin-like growth factor 1 (IGF-1) and low total triiodothyronine. Women health in this disorder is disturbed in several aspects including the skeletal system, cardiovascular system, and mental problems. Patients manifest a decrease in bone mass density, which is related to an increase in fracture risk. Therefore, osteopenia and osteoporosis are the main long-term complications of FHA. Cardiovascular complications include endothelial dysfunction and abnormal changes in the lipid profile. FHA patients present significantly higher depression and anxiety and also sexual problems compared to healthy subjects.
Vitale, J J; Broitman, S A
1981-09-01
There is in vitro and in vivo evidence to suggest that dietary lipids play a role in modulating immune function. A review of the current literature on the interrelationships among dietary lipids, blood cholesterol levels, immunosuppression, and tumorigenesis makes for a very strong argument that (a) immunosuppression may be causally related to lymphoproliferative disorders, as well as to tumorigenesis and (b) diets high in polyunsaturated fat, relative to diets high in saturated fat, are more immunosuppressive and are better promotors of tumorigenesis. The effects of dietary fat on immune function seem to be mediated though its component parts, the unsaturated fatty acids, specially linoleic, linolenic, and arachidonic. It is not clear how these components affect immune function. Several studies suggest that one effect is mediated by altering the lipid component of the cell membrane and thus its fluidity; the more fluid the membrane, the less responsive it is. Thus, fluidity of both immune cells and those to be destroyed or protected may be affected. The effects of saturated as well as unsaturated fatty acids may be mediated by modulating serum lipoprotein levels, prostaglandin metabolism, and cholesterol concentrations and metabolism.
Composing decoherence functionals
Boes, Paul
2016-01-01
Quantum Measure Theory (QMT) is a generalization of quantum theory where physical predictions are computed from a matrix known as decoherence functional (DF). Previous works have noted that, in its original formulation, QMT exhibits a problem with composability, since the composition of two decoherence functionals is, in general, not a valid decoherence functional. This does not occur when the DFs in question happen to be positive semidefinite (a condition known as strong positivity). In this paper, we study the concept of composability of DFs and its consequences for QMT. First, using the notion of composability, we settle an old problem in QMT regarding the definition of decoherent histories. Then we show that the problem of composability is much deeper than originally envisaged, since, for any $n$, there exists a DF that can co-exist with $n-1$ copies of itself, but not with $n$. Finally, we prove that the set of strongly positive DFs cannot be enlarged while remaining closed under composition. Furthermore...
Functional neuropeptidomics in invertebrates.
De Haes, Wouter; Van Sinay, Elien; Detienne, Giel; Temmerman, Liesbet; Schoofs, Liliane; Boonen, Kurt
2015-07-01
Neuropeptides are key messengers in almost all physiological processes. They originate from larger precursors and are extensively processed to become bioactive. Neuropeptidomics aims to comprehensively identify the collection of neuropeptides in an organism, organ, tissue or cell. The neuropeptidome of several invertebrates is thoroughly explored since they are important model organisms (and models for human diseases), disease vectors and pest species. The charting of the neuropeptidome is the first step towards understanding peptidergic signaling. This review will first discuss the latest developments in exploring the neuropeptidome. The physiological roles and modes of action of neuropeptides can be explored in two ways, which are largely orthogonal and therefore complementary. The first way consists of inferring the functions of neuropeptides by a forward approach where neuropeptide profiles are compared under different physiological conditions. Second is the reverse approach were neuropeptide collections are used to screen for receptor-binding. This is followed by localization studies and functional tests. This review will focus on how these different functional screening methods contributed to the field of invertebrate neuropeptidomics and expanded our knowledge of peptidergic signaling. This article is part of a Special Issue entitled: Neuroproteomics: Applications in Neuroscience and Neurology.
Functionalized Amorphous Aluminosilicates
Mesgar, Milad
Alkali treated aluminosilicate (geopolymer) was functionalized by surfactant to increase the hydrophobicity for making Pickering emulsion for the first part of this work. In the first part of this study, alkali treated metakaolin was functionalized with cetyltrimethylammonium bromide ((C16H33)N(CH 3)3Br, CTAB). The electrostatic interaction between this quaternary ammonium and the surface of the aluminosilicate which has negative charge has taken place. The particles then were used to prepare Pickering emulsion. The resulting stable dispersions, obtained very fast at very simple conditions with low ratio of aluminosilicate to liquid phase. In the second part, the interaction between geopolymer and glycerol was studied to see the covalent grafting of the geopolymer for making geopolymer composite. The composite material would be the basis material to be used as support catalyst, thin coating reagent and flame retardant material and so on, Variety of techniques, Thermogravimetric (TGA), Particle-induced X-ray emission (PIXE), FTIR, Solid state NMR, Powder X-ray diffraction (PXRD), BET surface area, Elemental analysis (CHN), TEM, SEM and Optical microscopy were used to characterize the functionalized geopolymer.
Directory of Open Access Journals (Sweden)
John W. Erdman
2015-10-01
Full Text Available Lutein is one of the most prevalent carotenoids in nature and in the human diet. Together with zeaxanthin, it is highly concentrated as macular pigment in the foveal retina of primates, attenuating blue light exposure, providing protection from photo-oxidation and enhancing visual performance. Recently, interest in lutein has expanded beyond the retina to its possible contributions to brain development and function. Only primates accumulate lutein within the brain, but little is known about its distribution or physiological role. Our team has begun to utilize the rhesus macaque (Macaca mulatta model to study the uptake and bio-localization of lutein in the brain. Our overall goal has been to assess the association of lutein localization with brain function. In this review, we will first cover the evolution of the non-human primate model for lutein and brain studies, discuss prior association studies of lutein with retina and brain function, and review approaches that can be used to localize brain lutein. We also describe our approach to the biosynthesis of 13C-lutein, which will allow investigation of lutein flux, localization, metabolism and pharmacokinetics. Lastly, we describe potential future research opportunities.
Hexagonalization of Correlation Functions
Fleury, Thiago
2016-01-01
We propose a nonperturbative framework to study general correlation functions of single-trace operators in $\\mathcal{N}=4$ supersymmetric Yang-Mills theory at large $N$. The basic strategy is to decompose them into fundamental building blocks called the hexagon form factors, which were introduced earlier to study structure constants using integrability. The decomposition is akin to a triangulation of a Riemann surface, and we thus call it hexagonalization. We propose a set of rules to glue the hexagons together based on symmetry, which naturally incorporate the dependence on the conformal and the R-symmetry cross ratios. Our method is conceptually different from the conventional operator product expansion and automatically takes into account multi-trace operators exchanged in OPE channels. To illustrate the idea in simple set-ups, we compute four-point functions of BPS operators of arbitrary lengths and correlation functions of one Konishi operator and three short BPS operators, all at one loop. In all cases,...
A CLASS OF FUNCTIONAL EQUATION AND FRACTAL INTERPOLATION FUNCTIONS
Institute of Scientific and Technical Information of China (English)
ShaZhen
1999-01-01
A new class of functional equation in C0(I) is investigated. It is proved that some class of FIF satisfies the functional equation. Another functional equation is constructed. Theirsolutions can approximate FIF arbitrarily. And a new approximate estimate between FIF andinterpolated function is given.
[Functional pathophysiology of consciousness].
Jellinger, Kurt A
2009-01-01
Consciousness (Latin conscientia "moral conscience"), according to the English philosopher John Locke (1632-1704) [103], is the awareness of all that occurs in the mind of a person, whereas the American philosopher John Searle (2000) defined it as "inner qualitative, subjective states and processes of awareness". In modern science it is defined as a continuous state of full awareness of the Self and one's relationship to the external and internal environment, describing the degree of wakefulness in which an organism recognizes stimuli. This widely discussed biological term for complex neuronal processes that allow an individuum to recognize itself and its environment and to act accordingly, has been and still is the subject of much research in philosophy and natural/neuroscience. Its definition is often used for awareness and recognition, too. While the Egyptians in the papyrus Edwin Smith already recognized the brain as the seat of consciousness, René Descartes (1644 [36]) believed its special structure should be "a small gland in the middle", but the anatomical structures and physiological processes involved in consciousness were elucidated only in the middle of the 20th century. Neuronal substrates include several functional networks that are hierarchically organized and cooperate functionally. The lowest level is the mesencephalic formatio reticularis and its projections to the thalamus that were identified als ascending reticular system (ARAS) by the classical experiments of Moruzzi and Magoun, whereas later analyses of patients with impaired consciousness provided further insights. The mesencephalic ARAS as motor of the function of higher structures projects 1. via the reticular thalamus diffusely to the cortex, 2. via hypothalamus to the basal forebrain and limbic system, and 3. to the medial raphe of the brainstem and locus coeruleus and their diffuse cortical projections. The reticular system is stimulated directly and indirectly via numerous collaterals
Collision-resistant hash function based on composition of functions
Ndoundam, Rene
2011-01-01
cryptographic hash function is a deterministic procedure that compresses an arbitrary block of numerical data and returns a fixed-size bit string. There exist many hash functions: MD5, HAVAL, SHA, ... It was reported that these hash functions are not longer secure. Our work is focused in the construction of a new hash function based on composition of functions. The construction used the NP-completeness of Three-dimensional contingency tables and the relaxation of the constraint that a hash function should also be a compression function.
Log-supermodular functions, functional clones and counting CSPs
Bulatov, Andrei A; Goldberg, Leslie Ann; Jerrum, Mark
2011-01-01
Motivated by a desire to understand the computational complexity of counting constraint satisfaction problems (counting CSPs), particularly the complexity of approximation, we study functional clones of functions on the Boolean domain, which are analogous to the familiar relational clones constituting Post's lattice. One of these clones is the collection of log-supermodular (lsm) functions, which turns out to play a significant role in classifying counting CSPs. In our study, we assume that non-negative unary functions (weights) are available. Given this, we prove that there are no functional clones lying strictly between the clone of lsm functions and the total clone (containing all functions). Thus, any counting CSP that contains a single non-lsm function is computationally as hard as any problem in #P. Furthermore, any non-trivial functional clone (in a sense that will be made precise below) contains the binary function "implies". As a consequence, all non-trivial counting CSPs (with non-negative unary wei...
Gelfand, I M; Shnol, E E
2002-01-01
The second in a series of systematic studies by a celebrated mathematician I. M. Gelfand and colleagues, this volume presents students with a well-illustrated sequence of problems and exercises designed to illuminate the properties of functions and graphs. Since readers do not have the benefit of a blackboard on which a teacher constructs a graph, the authors abandoned the customary use of diagrams in which only the final form of the graph appears; instead, the book's margins feature step-by-step diagrams for the complete construction of each graph. The first part of the book employs simple fu
DEFF Research Database (Denmark)
Sinden, Richard R.; E. Pearson, Christopher; N. Potaman, Vladimir
1998-01-01
This chapter discusses the structure and function of DNA. DNA occupies a critical role in cells, because it is the source of all intrinsic genetic information. Chemically, DNA is a very stable molecule, a characteristic important for a macromolecule that may have to persist in an intact form...... for a long period of time before its information is accessed by the cell. Although DNA plays a critical role as an informational storage molecule, it is by no means as unexciting as a computer tape or disk drive. The structure of the DNA described by Watson and Crick in 1953 is a right handed helix of two...
Matrix string partition function
Kostov, Ivan K; Kostov, Ivan K.; Vanhove, Pierre
1998-01-01
We evaluate quasiclassically the Ramond partition function of Euclidean D=10 U(N) super Yang-Mills theory reduced to a two-dimensional torus. The result can be interpreted in terms of free strings wrapping the space-time torus, as expected from the point of view of Matrix string theory. We demonstrate that, when extrapolated to the ultraviolet limit (small area of the torus), the quasiclassical expressions reproduce exactly the recently obtained expression for the partition of the completely reduced SYM theory, including the overall numerical factor. This is an evidence that our quasiclassical calculation might be exact.
Functional properties of vinegar.
Budak, Nilgün H; Aykin, Elif; Seydim, Atif C; Greene, Annel K; Guzel-Seydim, Zeynep B
2014-05-01
A variety of natural vinegar products are found in civilizations around the world. A review of research on these fermented products indicates numerous reports of health benefits derived by consumption of vinegar components. Therapeutic effects of vinegar arising from consuming the inherent bioactive components including acetic acid, gallic acid, catechin, ephicatechin, chlorogenic acid, caffeic acid, p-coumaric acid, and ferulic acid cause antioxidative, antidiabetic, antimicrobial, antitumor, antiobesity, antihypertensive, and cholesterol-lowering responses. The aims of this article are to discuss vinegar history, production, varieties, acetic acid bacteria, and functional properties of vinegars.
Directory of Open Access Journals (Sweden)
A. Calver
1997-01-01
Full Text Available This paper explores the establishment of transfer functions for describing the annual oscillation of unconfined aquifer water levels in response to effective precipitation. A simple saturated zone representation is developed to accompany the unsaturated zone mechanism. Practical examples are drawn from a sample of sites from the chalk and the Permo-Triassic sandstones of England and Wales. Modelled water levels are in many cases good. The technique is most appropriate within the usual range of fluctuation of aquifer water level, with no great change in influence of abstractions, and when it is acceptable to approximate the complexity of unsaturated zone processes in practical analysis.
DEFF Research Database (Denmark)
Bang, Anne Louise
2007-01-01
to the establishment of an initial framework for the project it has a focus on how to explore costumers and users emotional experiences with fabrics. The three year research project is based on experimental design research and the textile designer's competences and knowledge. During the research project exploring...... sensing of fabrics in function. It is proposed that tactile and visual sensing of fabrics is a way to investigate and express emotional utility values. The further purpose is to use experiments with repertory grid models as part of the mapping of the entire research project and also as a basis...
Design of functional metalloproteins.
Lu, Yi; Yeung, Natasha; Sieracki, Nathan; Marshall, Nicholas M
2009-08-13
Metalloproteins catalyse some of the most complex and important processes in nature, such as photosynthesis and water oxidation. An ultimate test of our knowledge of how metalloproteins work is to design new metalloproteins. Doing so not only can reveal hidden structural features that may be missing from studies of native metalloproteins and their variants, but also can result in new metalloenzymes for biotechnological and pharmaceutical applications. Although it is much more challenging to design metalloproteins than non-metalloproteins, much progress has been made in this area, particularly in functional design, owing to recent advances in areas such as computational and structural biology.
Aumasson, Jean-Philippe; Phan, Raphael; Henzen, Luca
2014-01-01
This is a comprehensive description of the cryptographic hash function BLAKE, one of the five final contenders in the NIST SHA3 competition, and of BLAKE2, an improved version popular among developers. It describes how BLAKE was designed and why BLAKE2 was developed, and it offers guidelines on implementing and using BLAKE, with a focus on software implementation. In the first two chapters, the authors offer a short introduction to cryptographic hashing, the SHA3 competition, and BLAKE. They review applications of cryptographic hashing, they describe some basic notions such as security de
Bayes multiple decision functions.
Wu, Wensong; Peña, Edsel A
2013-01-01
This paper deals with the problem of simultaneously making many (M) binary decisions based on one realization of a random data matrix X. M is typically large and X will usually have M rows associated with each of the M decisions to make, but for each row the data may be low dimensional. Such problems arise in many practical areas such as the biological and medical sciences, where the available dataset is from microarrays or other high-throughput technology and with the goal being to decide which among of many genes are relevant with respect to some phenotype of interest; in the engineering and reliability sciences; in astronomy; in education; and in business. A Bayesian decision-theoretic approach to this problem is implemented with the overall loss function being a cost-weighted linear combination of Type I and Type II loss functions. The class of loss functions considered allows for use of the false discovery rate (FDR), false nondiscovery rate (FNR), and missed discovery rate (MDR) in assessing the quality of decision. Through this Bayesian paradigm, the Bayes multiple decision function (BMDF) is derived and an efficient algorithm to obtain the optimal Bayes action is described. In contrast to many works in the literature where the rows of the matrix X are assumed to be stochastically independent, we allow a dependent data structure with the associations obtained through a class of frailty-induced Archimedean copulas. In particular, non-Gaussian dependent data structure, which is typical with failure-time data, can be entertained. The numerical implementation of the determination of the Bayes optimal action is facilitated through sequential Monte Carlo techniques. The theory developed could also be extended to the problem of multiple hypotheses testing, multiple classification and prediction, and high-dimensional variable selection. The proposed procedure is illustrated for the simple versus simple hypotheses setting and for the composite hypotheses setting
Computing with Harmonic Functions
Axler, Sheldon
2015-01-01
This document is the manual for a free Mathematica package for computing with harmonic functions. This package allows the user to make calculations that would take a prohibitive amount of time if done without a computer. For example, the Poisson integral of any polynomial can be computed exactly. This software can find exact solutions to Dirichlet, Neumann, and biDirichlet problems in R^n with polynomial data on balls, ellipsoids, and annular regions. It can also find bases for spaces of sphe...
Billiards correlation functions
Pedro, G; Pedro, Garrido; Giovanni, Gallavotti
1993-01-01
Abstract: We discuss various experiments on the time decay of velocity autocorrelation functions in billiards. We perform new experiments and find results which are compatible with an exponential mixing hypothesis, first put forward by [FM]: they do not seem compatible with the stretched exponentials believed, in spite of [FM], to describe the mixing. The analysis led us to several byproducts: we obtain information about the normal diffusive nature of the motion and we consider the probability distribution of the number of collisions in time $t_m$ (as $t_m\\to\\io$) finding a strong dependence on some geometric characteristics of the locus of the billiards obstacles.
Some Properties of Bent Functions
Institute of Scientific and Technical Information of China (English)
Ying Zhao
2007-01-01
First, this paper discusses and sums up some properties of a pair of functions p(x), q(x) that makes (y + 1)p(x) + yq(x) into a bent function. Then it discusses the properties of bent functions. Also, the upper and lower bounds of the number of bent functions on GF(2)2k are discussed.
A Primer on Functional Analysis
Yoman, Jerome
2008-01-01
This article presents principles and basic steps for practitioners to complete a functional analysis of client behavior. The emphasis is on application of functional analysis to adult mental health clients. The article includes a detailed flow chart containing all major functional diagnoses and behavioral interventions, with functional assessment…
Functional Foods for Women's Health.
Lindeman, Alice K.
2002-01-01
Describes functional foods for women's health (foods or food ingredients that provide health benefits beyond basic nutrition), explaining that both whole and modified foods can be included as functional foods. The paper discusses the history, regulation, and promotion of functional foods; consumer interest in functional foods; how to incorporate…
Directory of Open Access Journals (Sweden)
SCARLAT Razvan
2016-05-01
Full Text Available The functional clothing represents a sustainable development direction of in the field of technical textiles, a bridge between various activity domains, a solution to user’s complex requirements. The research and development potential in the field is supported by the new fibers/ yarns generation, the new technologies and the market niches, as well. Protective clothing is now a major part of textile classified under technical textile. Protective clothing refers to the garment and other fabric related items designed to protect the wearer from harsh environmental effects that results in injuries or death. The innovation, as a result of convergence processing technologies, consumer demands and what is viable on the market, defines the personal protective equipment field. In this article, we present the work of an ESD protective clothing development. Therefore, it has been applied a modern knitting technology, on 7E and 12E STOLL machines, using cotton and wool yarns as base yarn and conductive yarns for plaiting structures. Also, the optimal parameters establishment and the functional requirements are aspects of the research activity performed. The experimental models have been conducted in order to demonstrate the design concept used and choosing the optimal variant. The characterization of the developed experimental variants took into account the evaluation of physico-mechanical and electrical characteristics. From the electrical point of view, the variants have been mainly evaluated through “point to point” method in terms of electrical isolation efficiency dimensional changes analysis.
Functional diversity of laminins.
Domogatskaya, Anna; Rodin, Sergey; Tryggvason, Karl
2012-01-01
Laminins are a large family of conserved, multidomain trimeric basement membrane proteins that contribute to the structure of extracellular matrix and influence the behavior of associated cells, such as adhesion, differentiation, migration, phenotype stability, and resistance to anoikis. In lower organisms such as Hydra there is only one isoform of laminin, but higher organisms have at least 16 trimeric isoforms with varying degrees of cell/tissue specificity. In vitro protein and cell culture studies, gene manipulation in animals, and laminin gene mutations in human diseases have provided insight into the specific functions of some laminins, but the biological roles of many isoforms are still largely unexplored, mainly owing to difficulties in isolating them in pure form from tissues or cells. In this review, we elucidate the evolution of laminins, describe their molecular complexity, and explore the current knowledge of their diversity and functional aspects, including laminin-mediated signaling via membrane receptors, in vitro cell biology, and involvement in various tissues gained from animal model and human disease studies. The potential use of laminins in cell biology research and biotechnology is discussed.
Chitosan functional properties.
Shepherd, R; Reader, S; Falshaw, A
1997-06-01
Chitosan is a partially deacetylated polymer of N-acetyl glucosamine. It is essentially a natural, water-soluble, derivative of cellulose with unique properties. Chitosan is usually prepared from chitin (2 acetamido-2-deoxy beta-1,4-D-glucan) and chitin has been found in a wide range of natural sources (crustaceans, fungi, insects, annelids, molluscs, coelenterata etc.) However chitosan is only manufactured from crustaceans (crab and crayfish) primarily because a large amount of the crustacean exoskeleton is available as a by product of food processing. Squid pens (a waste byproduct of New Zealand squid processing) are a novel, renewable source of chitin and chitosan. Squid pens are currently regarded as waste and so the raw material is relatively cheap. This study was intended to assess the functional properties of squid pen chitosan. Chitosan was extracted from squid pens and assessed for composition, rheology, flocculation, film formation and antimicrobial properties. Crustacean chitosans were also assessed for comparison. Squid chitosan was colourless, had a low ash content and had significantly improved thickening and suspending properties. The flocculation capacity of squid chitosan was low in comparison with the crustacean sourced chitosans. However it should be possible to increase the flocculation capacity of squid pen chitosan by decreasing the degree of acetylation. Films made with squid chitosan were more elastic than crustacean chitosan with improved functional properties. This high quality chitosan could prove particularly suitable for medical/analytical applications.
Functionalism and consciousness.
Shoemaker, S
1993-01-01
It is widely held that a mental state and the subject's introspective belief about it are always 'distinct existences' and only contingently connected. This suggests that for each sort of mental state there could be a creature that is introspectively 'blind' with respect to states of that sort, meaning that while it is capable of having such states, and of conceiving of itself as having them, it is totally without introspective access to its states of that sort. It is argued here that introspective blindness with respect to many sorts of mental states, in particular beliefs and sensory states, is not a possibility, because it is incompatible with requirements of rationality that are internal to the functional roles that are constitutive of these states. Introspective accessibility is essential to the functional roles of such mental states when the conceptual and cognitive resources of the subject of those states are sufficiently rich to make beliefs and thoughts about them a possibility. This is a version of the view that such states are necessarily self-intimating and is incompatible with the perceptual model of introspection favoured by some functionalists as well as by many non-functionalists.
From mechanistic to functional behaviorism.
Moxley, R A
1992-11-01
A shift from mechanistic behaviorism to functional behaviorism is presented against the background of two historical traditions, one with an emphasis on form, the other with an emphasis on function. Skinner's work, which made more contributions to a functional behaviorism than to a mechanistic behaviorism, exemplifies this shift. The two traditions and an account of Skinner's development of functional relations are presented in order to show Skinner's contributions to aligning modern behavior analysis with the functional tradition.
Construction of bent functions from near-bent functions
DEFF Research Database (Denmark)
Leander, Gregor; McGuire, G.
2009-01-01
We give a construction of bent functions in dimension 2m from near-bent functions in dimension 2m - 1. in particular, we give the first ever examples of non-weakly-normal bent functions in dimensions 10 and 12, which demonstrates the significance of our construction.......We give a construction of bent functions in dimension 2m from near-bent functions in dimension 2m - 1. in particular, we give the first ever examples of non-weakly-normal bent functions in dimensions 10 and 12, which demonstrates the significance of our construction....
Integration a functional approach
Bichteler, Klaus
1998-01-01
This book covers Lebesgue integration and its generalizations from Daniell's point of view, modified by the use of seminorms. Integrating functions rather than measuring sets is posited as the main purpose of measure theory. From this point of view Lebesgue's integral can be had as a rather straightforward, even simplistic, extension of Riemann's integral; and its aims, definitions, and procedures can be motivated at an elementary level. The notion of measurability, for example, is suggested by Littlewood's observations rather than being conveyed authoritatively through definitions of (sigma)-algebras and good-cut-conditions, the latter of which are hard to justify and thus appear mysterious, even nettlesome, to the beginner. The approach taken provides the additional benefit of cutting the labor in half. The use of seminorms, ubiquitous in modern analysis, speeds things up even further. The book is intended for the reader who has some experience with proofs, a beginning graduate student for example. It might...
Physically Functional Materials
DEFF Research Database (Denmark)
2002-01-01
of information (holographic data storage), nonlinear optics (NLO), as photoconductors, photonic band-gap materials, electrically conducting materials, electroluminescent materials, piezo-electric materials, pyroelectric materials, magnetic materials, ferromagnetic materials, ferroelectric materials...... acids or peptides having azobenzenes or other physicially functional groups, e.g., photoresponsive groups, as side chains. These compounds may be synthesized using solid phase peptide synthesis techniques. Materials, e.g., thin films, comprising such compounds may be used for optical storage......, photorefractive materials, or materials in which light-induced conformational changes can be produced. Optical anisotropy may reversibly be generated with polarized laser light whereby a hologram is formed. First order diffraction efficiencies of up to around 80% have been obtained....
Heart function and hemodynamics
Institute of Scientific and Technical Information of China (English)
1993-01-01
930469 The effects of different ventricular pac-ing rates on cardiac hemodynamics and theirclinical significance.WEI Meng(魏盟),et al.Zhongshan Hosp,Shanghai Med Univ,Shanghai,200032.Shanghai Med J 1993;16(3):125—126.Changes of hemodynamics were investigated in26 patients at ventricular pacing rate of 60 to120,and 160 bpm.Effects of increasing ventricu-lar pacing rate on EF which were determined bygated blood pool scintigraphy were also studiedin another 11 patients.It is concluded that:1)inpatients with normal cardiac function as well asmost patients with cardiac insufficiency,the rela-tion of CO with increasing pacing rate can be il-
[Iron function and carcinogenesis].
Akatsuka, Shinya; Toyokuni, Shinya
2016-07-01
Though iron is an essential micronutrient for humans, the excess state is acknowledged to be associated with oncogenesis. For example, iron overload in the liver of the patients with hereditary hemocromatosis highly increases the risk of hepatocellular carcinoma. Also, as to asbestos-related mesothelioma, such kinds of asbestos with a higher iron content are considered to be more carcinogenic. Iron is a useful element, which enables fundamental functions for life such as oxygen carrying and electron transport. However, in the situation where organisms are unable to have good control of it, iron turns into a dangerous element which catalyzes generation of reactive oxygen. In this review, I first outline the relationships between iron and cancer in general, then give an explanation about iron-related animal carcinogenesis models.
Nag, Nagendra; Goldman, Lee M.; Balasubramanian, Sreeram; Sastri, Suri
2013-06-01
The requirements for modern aircraft are driving the need for conformal windows for future sensor systems. However, limitations on optical systems and the physical properties of optically transparent materials currently limit the geometry of existing windows and window assemblies to faceted assemblies of flat windows held in weight bearing frames. Novel material systems will have to be developed which combine different materials (e.g. ductile metals with transparent ceramics) into structures that combine transparency with structural integrity. Surmet's demonstrated ability to produce novel transparent ceramic/metal structures will allow us to produce such structures in the types of conformal shapes required for future aircraft applications. Furthermore, the ability to incorporate transparencies into such structures also holds out the promise of creating multi-functional windows which provide a broad range of capabilities that might include RF antennas and de-icing in addition to transparency. Recent results in this area will be presented.
DEFF Research Database (Denmark)
Andersen, C K; Andersen, K; Kragh-Sørensen, P
2000-01-01
Statistical analysis of cost data is often difficult because of highly skewed data resulting from a few patients who incur high costs relative to the majority of patients. When the objective is to predict the cost for an individual patient, the literature suggests that one should choose...... a regression model based on the quality of its predictions. In exploring the econometric issues, the objective of this study was to estimate a cost function in order to estimate the annual health care cost of dementia. Using different models, health care costs were regressed on the degree of dementia, sex, age......, marital status and presence of any co-morbidity other than dementia. Models with a log-transformed dependent variable, where predicted health care costs were re-transformed to the unlogged original scale by multiplying the exponential of the expected response on the log-scale with the average...
Thermodynamic Function of Life
Michaelian, K
2009-01-01
Darwinian Theory depicts life as being overwhelmingly consumed by a fight for survival in a hostile environment. However, from a thermodynamic perspective, life is a dynamic, out of equilibrium process, stabilizing and coevolving in concert with its abiotic environment. The living component of the biosphere of greatest mass, the plants and cyanobacteria, are involved in the transpiration of vast amounts of water. Transpiration is part of the global water cycle, and it is this cycle that distinguishes Earth from its life barren neighboring planets, Venus and Mars. The water cycle, including the absorption of sunlight in the biosphere, is by far the greatest entropy producing process occurring on Earth. Life, from this perspective, can therefore be viewed as performing an important thermodynamic function; acting as a dynamic catalyst by aiding process such as the water cycle, hurricanes, and ocean and wind currents to produce entropy. The role of animals in this view is that of unwitting but dedicated servants ...
Billiards correlation functions
Energy Technology Data Exchange (ETDEWEB)
Garrido, P.L. [Universidad de Granada (Spain); Gallavotti, G. [Universita di Roma (Italy)
1994-07-01
We discuss various experiments on the time decay of velocity autocorrelation functions in billiards. We perform new experiments and find results which are compatible with an exponential mixing hypothesis first put forward by Friedman and Martin (GM): they do not seem compatible with the stretched exponentials believed, in spite of FM and more recently of Chernov, to describe the mixing. The analysis leads to several byproducts: we obtain information about the normal diffusive nature of the motion and we consider the probability distribution of the number of collisions in time t{sub m} (as t{sub m} {yields} {infinity}), finding a strong dependence on some geometric characteristics of the locus of the billiard obstacles.
Indirect photobiomodulation in functional networks
Liu, Timon Cheng-Yi; Zhu, Wei-Wei; Yang, Xiang-Bo
2012-12-01
Photobiomodulation (PBM) is a non-damaged modulation of laser irradiation or monochromatic light (LI) on a biosystem function. It depends on whether the function is in its function-specific homeostasis (FSH), a negative feedback response for the function to be performed perfectly. Many redundant pathways (RPs) maintain the same cellular function. The full activation of any of RPs can maintain a normal function in its FSH, but partial activation of all the RPs can only maintain a dysfunctional function far from its FSH. A PBM may self-adaptively modulate the activation of a partially activated RP of a normal function until it is fully activated and the normal function is then upgraded. This PBM is called indirect PBM (iPBM). The iPBM on cells such as tumor cells, myoblast cells and fibroblasts and other biosystems and their applications would be reviewed in this paper.
Tamoxifen and ovarian function.
Directory of Open Access Journals (Sweden)
Martine Berliere
Full Text Available BACKGROUND: Some studies suggest that the clinical parameter "amenorrhea" is insufficient to define the menopausal status of women treated with chemotherapy or tamoxifen. In this study, we investigated and compared the ovarian function defined either by clinical or biological parameters in pre-menopausal breast cancer patients treated with tamoxifen administered as adjuvant therapy. MATERIALS AND METHODS: Between 1999 and 2003, 138 premenopausal patients consecutively treated for early breast cancer were included. Sixty-eight received tamoxifen in monotherapy as the only adjuvant systemic treatment (Group I and 70 were treated with tamoxifen after adjuvant chemotherapy (Group II. All patients had a confirmed premenopausal status based on clinical parameters and hormonal values at study entry. They were followed prospectively every 3 months for 3 years: menses data, physical examination and blood tests (LH, FSH, 17-beta-estradiol. Vaginal ultrasonography was carried out every 6 months. After 3 years, prospective evaluation was completed and monitoring of ovarian function was performed as usual in our institution (1x/year. All data were retrospectively evaluated in 2011. RESULTS: Three patients were excluded from the study in group I and 2 were excluded in group II. Patients were divided into 4 subgroups according to clinical data, i.e. menses patterns. These patterns were assessed by questionnaires. a: Regular menses (>10 cycles/year b: Oligomenorrhea (5 to 9 cycles/year c: Severe oligomenorrhea (1 to 4 cycles/year d: Complete amenorrhea Estrogen levels did not appear to have any impact on disease-free survival rates after 3 or 8 years. FSH values were also documented and analyzed. They exhibited the same profile as estradiol values. CONCLUSIONS: Amenorrhea is an insufficient parameter to define menopausal status in patients receiving tamoxifen. Low estradiol levels must be coupled with other biological parameters to characterize endocrine status
[Functional histology of dermis].
Prost-Squarcioni, C; Fraitag, S; Heller, M; Boehm, N
2008-01-01
The skin is composed of epidermis, dermis and subcutaneous tissue that interconnect anatomically. The dermis is an integrated system of fibrous and amorphous connective tissue that accommodates nerve and vascular networks, epidermally derived appendages, fibroblasts, macrophages and mast cells. Elastic and collagen tissue are the main types of fibrous connective tissue. The elastic connective tissue is assembled in a continuous network including mature elastic fibers, immature elaunin fibers and oxytalan fibers. Mature elastic fibers and elaunin have microfibrillar and amorphous matrix components while oxytalan fibers only contain microfibrils. Several molecules have been identified as constituents of the elastic fibers. Among the most characterized of these molecules is elastin in amorphous matrix, fibrillins 1 and 2 and LTBP-2 (ligand of latent TGFbeta) in microfibrils and fibulins which interconnect elastin and fibrillins. Elastic fibers provides elasticity to the skin. Under electron microscope, collagen fibers appears as of bundles of periodically banded fibrils which are composed of collagens types I, III and V; type V collagen is believed to assist in regulating fibril diameter. They are associated with FACITs (fibril-associated collagen with interrupted triple helixes) collagens types XIV et XVI. Collagen fibers provide tensile strength to the skin. Non fibrous connective tissue molecules include finely filamentous glycoproteins, glycosaminoglycans and proteoglycans of "the ground substance" (hyaluronic acid and chondroitin sulphate, dermatan sulphate, versican, decorin). Fibroblasts, macrophages and mast cells are regular residents of the dermis. The main function of these cells are well known. Fibroblasts are responsible for the synthesis and the degradation of fibrous and non fibrous connective tissue matrix proteins. Macrophages are phagocytic; they process and present antigen to immunocompetent lymphoid cells. Mast cells are responsible for Ig
Lyapunov functionals and stability of stochastic functional differential equations
Shaikhet, Leonid
2013-01-01
Stability conditions for functional differential equations can be obtained using Lyapunov functionals. Lyapunov Functionals and Stability of Stochastic Functional Differential Equations describes the general method of construction of Lyapunov functionals to investigate the stability of differential equations with delays. This work continues and complements the author’s previous book Lyapunov Functionals and Stability of Stochastic Difference Equations, where this method is described for discrete- and continuous-time difference equations. The text begins with a description of the peculiarities of deterministic and stochastic functional differential equations. There follow basic definitions for stability theory of stochastic hereditary systems, and a formal procedure of Lyapunov functionals construction is presented. Stability investigation is conducted for stochastic linear and nonlinear differential equations with constant and distributed delays. The proposed method is used for stability investigation of di...
Generalized -deformed correlation functions as spectral functions of hyperbolic geometry
Bonora, L.; Bytsenko, A. A.; Guimarães, M. E. X.
2014-08-01
We analyze the role of vertex operator algebra and 2d amplitudes from the point of view of the representation theory of infinite-dimensional Lie algebras, MacMahon and Ruelle functions. By definition p-dimensional MacMahon function, with , is the generating function of p-dimensional partitions of integers. These functions can be represented as amplitudes of a two-dimensional c = 1 CFT, and, as such, they can be generalized to . With some abuse of language we call the latter amplitudes generalized MacMahon functions. In this paper we show that generalized p-dimensional MacMahon functions can be rewritten in terms of Ruelle spectral functions, whose spectrum is encoded in the Patterson-Selberg function of three-dimensional hyperbolic geometry.
On -Functions for Laguerre Function Expansions of Hermite Type
Indian Academy of Sciences (India)
Błażej Jan Wróbel
2011-02-01
We examine weighted $L^p$ boundedness of -functions based on semi-groups related to multi-dimensional Laguerre function expansions of Hermite type. A technique of vector-valued Calderón–Zygmund operators is used.
Directory of Open Access Journals (Sweden)
Lingjie Lei
2016-08-01
Full Text Available Increasing attention has recently been focused on the linkages between plant functional traits and ecosystem functioning. A comprehensive understanding of these linkages can facilitate to address the ecological consequences of plant species loss induced by human activities and climate change, and provide theoretical support for ecological restoration and ecosystem management. In recent twenty years, the evidence of strong correlations between plant functional traits and changes in ecosystem processes is growing. More importantly, ecosystem functioning can be predicted more precisely, using plant functional trait diversity (i.e., functional diversity than species diversity. In this paper, we first defined plant functional traits and their important roles in determining ecosystem processes. Then, we review recent advances in the relationships between ecosystem functions and plant functional traits and their diversity. Finally, we propose several important future research directions, including (1 exploration of the relationships between aboveground and belowground plant traits and their roles in determining ecosystem functioning, (2 incorporation of the impacts of consumer and global environmental change into the correlation between plant functional traits and ecosystem functioning, (3 effects of functional diversity on ecosystem multifunctionality, and (4 examination of the functional diversity-ecosystem functioning relationship at different temporal and spatial scales.
Methylmercury toxicity and functional programming
DEFF Research Database (Denmark)
Grandjean, Philippe
2007-01-01
PURPOSE: Adverse health effects of developmental toxicants may induce abnormal functional programming that leads to lasting functional deficits. This notion is considered from epidemiological evidence using developmental methylmercury neurotoxicity as an example. MOST IMPORTANT FINDINGS...... of certain brain functions, thereby causing confounding bias. The functional deficits caused by prenatal methylmercury exposure appear to be permanent, and their extent may depend on the joint effect of toxicants and nutrients. PRINCIPAL CONCLUSIONS: The lasting functional changes caused...... by neurodevelopmental methylmercury toxicity fit into the pattern of functional programming, with effects opposite to those linked to beneficial stimuli....
Generalization of Hopf Functional Equation
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
This paper generalizes the Hopf functional equation in order to apply it to a wider class of not necessarily incompressible fluid flows. We start by defining characteristic functionals of the velocity field, the density field and the temperature field of a compressible field. Using the continuity equation, the Navier-Stokes equations and the equation of energy we derive a functional equation governing the motion of an ideal gas flow and a van der Waals gas flow, and then give some general methods of deriving a functional equation governing the motion of any compressible fluid flow. These functional equations can be considered as the generalization of the Hopf functional equation.
Reflection algebra and functional equations
Energy Technology Data Exchange (ETDEWEB)
Galleas, W., E-mail: w.galleas@uu.nl; Lamers, J., E-mail: j.lamers@uu.nl
2014-09-15
In this work we investigate the possibility of using the reflection algebra as a source of functional equations. More precisely, we obtain functional relations determining the partition function of the six-vertex model with domain-wall boundary conditions and one reflecting end. The model's partition function is expressed as a multiple-contour integral that allows the homogeneous limit to be obtained straightforwardly. Our functional equations are also shown to give rise to a consistent set of partial differential equations satisfied by the partition function.
RELAXATION OF FUNCTIONALS INVOLVING HOMOGENEOUS FUNCTIONS AND INVARIANCE OF ENVELOPES
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
The authors compute the quasiconvex envelope of certain functions defined on the space Mmn of real m× n matrices via a homogeneous function on Mmn. They also deduce invariance properties for various convex envelopes from corresponding invariance properties satisfied by a function. Some applications related in particular to nonlinear elasticity are given.
THE BOREL DIRECTIONS OF ALGEBROIDAL FUNCTION AND ITS COEFFICIENT FUNCTIONS
Institute of Scientific and Technical Information of China (English)
张少华; 张晓梅; 孙道椿
2014-01-01
In this article, the relationship between the Borel direction of algebroidal function and its coefficient functions is studied for the first time. To begin with, several theorems of algebroidal functions in unit disk are proved. By these theorems, some interesting conclusions are obtained.
Convergence of Infinite Composition of Entire Functions
Kojima, Shota
2010-01-01
The purpose of the present article is to obtain the condition that the function defined by infinite composition of entire functions becomes an entire function. Moreover, as an example of such functions, we study a function called Poincare function.
Energy Technology Data Exchange (ETDEWEB)
Sorichter, S. [Universitaetsklinikum Freiburg, Abteilung Pneumologie, Freiburg (Germany)
2009-08-15
The term lung function is often restricted to the assessment of volume time curves measured at the mouth. Spirometry includes the assessment of lung volumes which can be mobilised with the corresponding flow-volume curves. In addition, lung volumes that can not be mobilised, such as the residual volume, or only partially as FRC and TLC can be measured by body plethysmography combined with the determination of the airway resistance. Body plethysmography allows the correct positioning of forced breathing manoeuvres on the volume-axis, e.g. before and after pharmacotherapy. Adding the CO single breath transfer factor (T{sub LCO}), which includes the measurement of the ventilated lung volume using He, enables a clear diagnosis of different obstructive, restrictive or mixed ventilatory defects with and without trapped air. Tests of reversibility and provocation, as well as the assessment of inspiratory mouth pressures (PI{sub max}, P{sub 0.1}) help to classify the underlying disorder and to clarify treatment strategies. For further information and to complete the diagnostic of disturbances of the ventilation, diffusion and/or perfusion (capillar-)arterial bloodgases at rest and under physical strain sometimes amended by ergospirometry are recommended. Ideally, lung function measurements are amended by radiological and nuclear medicine techniques. (orig.) [German] Unter dem Begriff Lungenfunktion wird die Bestimmung der Lungenvolumina am Mund verstanden. Dabei werden die mobilisierbaren Lungenvolumina mit den zugehoerigen Fluss-Volumen-Kurven mittels Spirometrie und Ganzkoerperplethysmographie (GKP) und die nicht (RV) und teilweise mobilisierbaren Lungenvolumina (FRC, TLC) einschliesslich der Atemwegswiderstaende bestimmt. Die GKP ermoeglicht zusaetzlich die korrekte (Volumenachsen-)Positionierung der forcierten Atemmanoever. Dieses erlaubt eine uebersichtlichere graphische Darstellung z. B. vor und nach der Applikation pharmakologisch wirksamer Substanzen. Wird die GKP
Cognition and brain functional aging
Directory of Open Access Journals (Sweden)
Hui-jie LI
2014-03-01
Full Text Available China has the largest population of elderly adults. Meanwhile, it is one of the countries showing fastest aging speed in the world. Aging processing is always companied with a series of brain structural and functional changes, which result in the decline of processing speed, working memory, long-term memory and executive function, etc. The studies based on functional magnetic resonance imaging (fMRI found certain aging effects on brain function activation, spontaneous activity and functional connectivity in old people. However, few studies have explored the brain functional curve during the aging process while most previous studies explored the differences in the brain function between young people and old people. Delineation of the human brain functional aging curve will promote the understanding of brain aging mechanisms and support the normal aging monitoring and early detection of abnormal aging changes. doi: 10.3969/j.issn.1672-6731.2014.03.005
Functional interpretation and inductive definitions
Avigad, Jeremy
2008-01-01
Extending G\\"odel's \\emph{Dialectica} interpretation, we provide a functional interpretation of classical theories of positive arithmetic inductive definitions, reducing them to theories of finite-type functionals defined using transfinite recursion on well-founded trees.
Interpolation in Spaces of Functions
Directory of Open Access Journals (Sweden)
K. Mosaleheh
2006-03-01
Full Text Available In this paper we consider the interpolation by certain functions such as trigonometric and rational functions for finite dimensional linear space X. Then we extend this to infinite dimensional linear spaces
Functional Abdominal Pain in Children
... functional abdominal pain. Functional abdominal pain can be intermittent (recurrent abdominal pain or RAP) or continuous. Although ... tests are needed or whether a trial of diet changes, stress management or medication may be started. ...
Cryptographic Hash functions - a review
Directory of Open Access Journals (Sweden)
Rajeev Sobti
2012-03-01
Full Text Available Cryptographic Hash functions are used to achieve a number of security objectives. In this paper, we bring out the importance of hash functions, its various structures, design techniques, attacks and the progressive recent development in this field.
DEFF Research Database (Denmark)
Elsmore, Matthew James
and trademark law – I have tried to weave a familiar legal discussion into a festive setting. Hence, I stage an office IP party and place it (and the legal discussion) loosely in the ‘happiest’ of settings, Denmark, and at Christmas time (well, just after). A promising start, perhaps. What emerges is a look...... at the main characters at ‘IP-World’ (where you work), and a special focus on trademark law through the office party. From there, you seek some counsel. The office party piece (Part I) is an entry point into a fuller discussion (which begins in Part II); hence acting as aperitif to a main course. (For those...... is an inherent work-in-progress, and hence labelled ‘Draft’. Moreover, this precise point, and my intended wider audience, also helps explain the inclusion of this essay on SSRN. Note: This draft essay has not been reviewed. Thus, any comments on its form and function are welcome, either via the IPKat post...
[Functional gastrointestinal disorders].
Vogt, W
2007-11-21
Functional gastrointestinal disorders particularly dyspepsia an irritable bowel syndrome are frequent problems for the general practitioner and also for the specialist. Both are diseases and not only a kind of discomfort. The high frequency of dispepsia and irritable bowel syndrome induces very high direct and indirect charges. Both diseases depend on a number of factors or causes, for whom the evidence is not good. But there are good experimental data for the visceral hypersensitivity as one of the main factors. Gastroscopy is the most important examination in the diagnosis of dyspepsia. Endoscopy has to be done in all patients with alarm symptoms an in all patients older than 45 years. The therapy of dyspepsia is an empirical one. The eradication of Helicobacter pylori is a therapeutical option, but only 8% of the patients will have benefit for a long time. Other therapeutical options are the use of proton-pump inhibitors, prokinetics or phytotherapeutics. The therapy of the irritable bowel syndrome depends on the subtype of the disease (diarrhea, constipation, abdominal pain, bloating). First of all a good doctor-patient relationship is mandatory. Furthermore the use of dietary fibre, antidiarrhoeics, laxatives and muscle relaxants may be beneficial. And phytotherapeutics can be an additional therapeutic approach.
Adolfsson, Oskar; Meydani, Simin Nikbin; Russell, Robert M
2004-08-01
In recent years, numerous studies have been published on the health effects of yogurt and the bacterial cultures used in the production of yogurt. In the United States, these lactic acid-producing bacteria (LAB) include Lactobacillus and Streptococcus species. The benefits of yogurt and LAB on gastrointestinal health have been investigated in animal models and, occasionally, in human subjects. Some studies using yogurt, individual LAB species, or both showed promising health benefits for certain gastrointestinal conditions, including lactose intolerance, constipation, diarrheal diseases, colon cancer, inflammatory bowel disease, Helicobacter pylori infection, and allergies. Patients with any of these conditions could possibly benefit from the consumption of yogurt. The benefits of yogurt consumption to gastrointestinal function are most likely due to effects mediated through the gut microflora, bowel transit, and enhancement of gastrointestinal innate and adaptive immune responses. Although substantial evidence currently exists to support a beneficial effect of yogurt consumption on gastrointestinal health, there is inconsistency in reported results, which may be due to differences in the strains of LAB used, in routes of administration, or in investigational procedures or to the lack of objective definition of "gut health." Further well-designed, controlled human studies of adequate duration are needed to confirm or extend these findings.
Cluster functional renormalization group
Reuther, Johannes; Thomale, Ronny
2014-01-01
Functional renormalization group (FRG) has become a diverse and powerful tool to derive effective low-energy scattering vertices of interacting many-body systems. Starting from a free expansion point of the action, the flow of the RG parameter Λ allows us to trace the evolution of the effective one- and two-particle vertices towards low energies by taking into account the vertex corrections between all parquet channels in an unbiased fashion. In this work, we generalize the expansion point at which the diagrammatic resummation procedure is initiated from a free UV limit to a cluster product state. We formulate a cluster FRG scheme where the noninteracting building blocks (i.e., decoupled spin clusters) are treated exactly, and the intercluster couplings are addressed via RG. As a benchmark study, we apply our cluster FRG scheme to the spin-1/2 bilayer Heisenberg model (BHM) on a square lattice where the neighboring sites in the two layers form the individual two-site clusters. Comparing with existing numerical evidence for the BHM, we obtain reasonable findings for the spin susceptibility, the spin-triplet excitation energy, and quasiparticle weight even in coupling regimes close to antiferromagnetic order. The concept of cluster FRG promises applications to a large class of interacting electron systems.
Weinstein, Steven
2016-01-01
Noise is widely understood to be something that interferes with a signal or process. Thus, it is generally thought to be destructive, obscuring signals and interfering with function. However, early in the 20th century, mechanical engineers found that mechanisms inducing additional vibration in mechanical systems could prevent sticking and hysteresis. This so-called "dither" noise was later introduced in an entirely different context at the advent of digital information transmission and recording in the early 1960s. Ironically, the addition of noise allows one to preserve information that would otherwise be lost when the signal or image is digitized. As we shall see, the benefits of added noise in these contexts are closely related to the phenomenon which has come to be known as stochastic resonance, the original version of which appealed to noise to explain how small periodic fluctuations in the eccentricity of the earth's orbit might be amplified in such a way as to bring about the observed periodic transiti...
Gracovetsky, S
1986-07-01
In spite of the considerable effort which has been invested in attempts to understand the mechanism of human spines, substantial controversy remains, particularly in connection with assumptions which have to be made by those engaged in biological modelling. The hypothesis presented here is that the living joint has stress sensors driving a feedback mechanism, an arrangement which could react to imposed loads by modifying muscular action in such a way as to minimize stress at the joints and therefore the risk of injury. A theory of this kind gives an image of the spine not in terms of a spatial picture, as would a CAT scan, but in terms of stresses, forces and moments acting at the intervertebral joints. Calculations show that the erectores spinae alone cannot support more than about 50 kg; there must be some other mechanism to explain man's ability substantially to exceed that load. It is suggested that the interaction between the erectores spinae and the abdominals are of fundamental importance in the function of the spine; how they are co-ordinated during the lifting of weights is examined in detail. The theory resulting from this hypothesis is used to relate spinal injury and an injured subject's posture and behaviour. A mathematical formulation permits an objective evaluation of the spine, and a procedure for determining an automatic diagnosis of lumbar spine disabilities is proposed.
COTTAGE CHEESE PRODUCTS FUNCTIONALITY
Directory of Open Access Journals (Sweden)
L. V. Golubeva
2015-01-01
Full Text Available Cottage cheese products holds a significant place among the dairy and milk-containing products. The range of products includes cheese: cheese, pastes, creams, cakes, etc. Such diversity can be attributed to their popularity among the population and benefit brought by the body from regular use. Curd protein is much better and easier to digest by the body than protein fish, meat or milk. Rich curd products lysine and methionine. Minerals contained in cheese products have a positive effect on bone formation and structure of tissues. The composition of curd products, in addition to cheese and dairy ingredients may include non-dairy ingredients origin. Today, for the production of cheese products use the most advanced technologies to further enrich its structure and significantly improve the nutritional value. Pine nut is widely used in the manufacture of many dairy products. But, in most cases, the production of dairy products as a filler used pine nut cake, which deprives the finished product valuable cedar oil. The authors proposed a technology for producing curd product with the addition of pine nuts and honey (pine nuts and fructose. Compatible with cream cheese filling insertion determined sensory organoleptic point scale. he optimum dosage of components: pine nuts – 5 %, honey – 10 % fructose – 7 %. Technological process of cottage cheese product is different from the traditional operations training components and their introduction into the finished cheese. Identify indicators of quality of the new product. Production of curd products thus expanding the range of dairy products functional orientation.
Functional neuroanatomy of tics.
Neuner, Irene; Schneider, Frank; Shah, N Jon
2013-01-01
The therapeutic success of haloperidol in the treatment of Tourette syndrome (TS) put an end to the discussion about a "hysteric" or "neurotic" origin of TS. The cortico-striato-thalamo-cortical circuit has been identified as an underlying neurobiological correlate of TS. In this review we explore the main findings of structural alterations in TS including cortical areas, basal ganglia, hippocampus, amygdala, midbrain, and cerebellum. Based on the structural changes we examine the functional pattern described by the findings of fMRI and (15)O-PET/(18)FDG PET investigations. From the neuroimaging findings a cortical origin of the generation of tics is indicated. Future research on the neuronal footprint of TS should be directed towards addressing the question of which patterns of connectivity distinguish individuals in whom tics disappear during early adulthood from those in whom the tics persist. The understanding of this pathomechanism could provide a key on how to influence dysconnectivity in TS, for example, by more specific pharmaceutical intervention or by individually adopted EEG and/or fMRI neurofeedback.
Topics on nonlinear generalized functions
Colombeau, J F
2011-01-01
The aim of this paper is to give the text of a recent introduction to nonlinear generalized functions exposed in my talk in the congress gf2011, which was asked by several participants. Three representative topics were presented: two recalls "Nonlinear generalized functions and their connections with distribution theory", "Examples of applications", and a recent development: "Locally convex topologies and compactness: a functional analysis of nonlinear generalized functions".
Structure functions at large x
Zhang, Z
2002-01-01
Structure function data together with other measurements from fixed-target deep inelastic scattering and hadron-hadron collider experiments which contribute to our knowledge of the parton density functions are reviewed. The inclusive cross-section measurements of neutral and charged current interactions at HERA are presented and their impact on the parton density functions is discussed. Future prospects for an improved knowledge of the parton density functions at large x are briefly mentioned.
Functional neuroimaging of sleep disorders.
Nofzinger, Eric A
2008-01-01
Functional neuroimaging methods provide a means to understand brain function in patients with sleep disorders. This paper summarizes functional neuroimaging findings in sleep disorders patients, and studies addressing the pharmacology of sleep and sleep disorders. Areas in which functional neuroimaging methods may be helpful in sleep medicine, and in which future development is advised, include: 1) clarification of pathophysiology; 2) aid in differential diagnosis; 3) assessment of treatment response; 4) guiding new drug development; and 5) monitoring treatment response.
DEFF Research Database (Denmark)
Henglein, Fritz
2009-01-01
What is a sorting function—not a sorting function for a given ordering relation, but a sorting function with nothing given? Formulating four basic properties of sorting algorithms as defining requirements, we arrive at intrinsic notions of sorting and stable sorting: A function is a sorting funct...... are derivable without compromising data abstraction. Finally we point out that stable sorting functions as default representations of ordering relations have the advantage of permitting linear-time sorting algorithms; inequality tests forfeit this possibility....
Protein Functionality in Food Systems
Institute of Scientific and Technical Information of China (English)
WANG Panpan
2010-01-01
The structure,shape,color,smell and taste of food were decided by protein functionality.The utilization of protein will improve by changing the protein functionality.Protein functionality is also advantage to maintain and utilize the nutrition of food.This paper summarized the nature,classification,factors and prospect of protein functionality.It ccn provide a theoretical basis for application of protein in food industry.
A functional RG equation for the c-function
DEFF Research Database (Denmark)
Codello, A.; D'Odorico, G.; Pagani, C.
2014-01-01
After showing how to prove the integrated c-theorem within the functional RG framework based on the effective average action, we derive an exact RG flow equation for Zamolodchikov's c-function in two dimensions by relating it to the flow of the effective average action. In order to obtain a non......-trivial flow for the c-function, we will need to understand the general form of the effective average action away from criticality, where nonlocal invariants, with beta functions as coefficients, must be included in the ansatz to be consistent. Then we apply our construction to several examples: exact results......, local potential approximation and loop expansion. In each case we construct the relative approximate c-function and find it to be consistent with Zamolodchikov's c-theorem. Finally, we present a relation between the c-function and the (matter induced) beta function of Newton's constant, allowing us...
Building indifferentiable compression functions from the PGV compression functions
DEFF Research Database (Denmark)
Gauravaram, P.; Bagheri, Nasour; Knudsen, Lars Ramkilde
2016-01-01
Preneel, Govaerts and Vandewalle (PGV) analysed the security of single-block-length block cipher based compression functions assuming that the underlying block cipher has no weaknesses. They showed that 12 out of 64 possible compression functions are collision and (second) preimage resistant. Black...... cipher is ideal. We address the problem of building indifferentiable compression functions from the PGV compression functions. We consider a general form of 64 PGV compression functions and replace the linear feed-forward operation in this generic PGV compression function with an ideal block cipher...... independent of the one used in the generic PGV construction. This modified construction is called a generic modified PGV (MPGV). We analyse indifferentiability of the generic MPGV construction in the ideal cipher model and show that 12 out of 64 MPGV compression functions in this framework...
Reflection algebra and functional equations
Galleas, W.; Lamers, J.
2014-01-01
In this work we investigate the possibility of using the reflection algebra as a source of functional equations. More precisely, we obtain functional relations determining the partition function of the six-vertex model with domain-wall boundary conditions and one reflecting end. The model's partitio
[Diagnosis of functional bowel diseases].
Kruis, W
2007-02-28
Functional bowel disorders cause frequent doctor visits. The term comprises various disease entities. Most frequent are the irritable bowel syndrome, functional constipation and functional diarrhea. An exact history plays an outstanding role for the diagnosis of all these entities. History either confirms a positive diagnosis or initiates some complementary investigations. Redundant and dangerous technical procedures should be avoided in the diagnostic work up.
Applications of functionalized ionic liquids
Institute of Scientific and Technical Information of China (English)
LI; Xuehui; ZHAO; Dongbin; FEI; Zhaofu; WANG; Lefu
2006-01-01
Recent developments of the synthesis and applications of functionalized ionic liquids(including dual-functionalized ionic liquids) have been highlighted in this review. Ionic liquids are attracting attention as alternative solvents in green chemistry, but as more functionalized ILs are prepared, a greater number of applications in increasingly diverse fields are found.
DEFF Research Database (Denmark)
Madsen, Per Printz
1999-01-01
The purpose of this paper is to describe a neural network (SNN), that is based on Shannons ideas of reconstruction of a real continuous function from its samples. The basic function, used in this network, is the Sinc-function. Two learning algorithms are described. A simple one called IM...
Ecological Correlates of Family Functioning.
Meyers, Steven A.; Varkey, Soji; Aguirre, Angela M.
2002-01-01
Explores how parents' psychological functioning, social relationships, and demographic characteristics relate to family functioning with a sample of 197 participants. Significant associations between predictor variables and family functioning were found as rated by mothers, caseworkers, and coders of family interaction tasks. (JDM)
Comments on the slope function
Kim, Minkyoo
2016-01-01
The exact slope function was first proposed in $SL(2)$ sector and generalized to $SU(2)$ sector later. In this note, we consider the slope function in $SU(1|1)$ sector of ${\\cal N}=4$ SYM. We derive the quantity through the method invented by N. Gromov and discuss about its validity. Further, we give comments on the slope function in deformed SYM.
A lung function information system
A.F.M. Verbraak (Anton); E.J. Hoorn (Ewout); J. de Vries (Julius); J.M. Bogaard (Jan); A. Versprille (Adrian)
1991-01-01
markdownabstractAbstract A lung function information system (LFIS) was developed for the data analysis of pulmonary function tests at different locations. This system was connected to the hospital information system (HIS) for the retrieval of patient data and the storage of the lung function varia
Functional Similarity and Interpersonal Attraction.
Neimeyer, Greg J.; Neimeyer, Robert A.
1981-01-01
Students participated in dyadic disclosure exercises over a five-week period. Results indicated members of high functional similarity dyads evidenced greater attraction to one another than did members of low functional similarity dyads. "Friendship" pairs of male undergraduates displayed greater functional similarity than did "nominal" pairs from…
Normal Families and Shared Functions
Institute of Scientific and Technical Information of China (English)
WANG Xue-qin; LEI Chun-lin
2015-01-01
Let k be a positive integer, let h be a holomorphic function in a domain D, h 6≡0 and let F be a family of nonvanishing meromorphic functions in D. If each pair of functions f and g in F , f (k) and g(k) share h in D, then F is normal in D.
Simulation Methods for Functional Materials
Institute of Scientific and Technical Information of China (English)
Youqi Yang
2004-01-01
@@ Functional materials embrace a broad area, ranging from functional information materials to special polymers, from special chemicals for printing to materials used in making paints. Inasmuch as most functional materials are particulate, the present contribution is considered pertinent to the present FORUM.
Evolutionary Design of Boolean Functions
Institute of Scientific and Technical Information of China (English)
WANG Zhang-yi; ZHANG Huan-guo; QIN Zhong-ping; MENG Qing-shu
2005-01-01
We use evolutionary computing to synthesize Boolean functions randomly. By using specific crossover and mutation operator in evolving process and modifying search space and fitness function, we get some high non-linearity functions which have other good cryptography characteristics such as autocorrelation etc. Comparing to other heuristic search techniques, evolutionary computing approach is more effective because of global search strategy and implicit parallelism.
Construction of optimized Boolean functions
Institute of Scientific and Technical Information of China (English)
CHEN Wei; YANG Yi-xian; NIU Xin-xin
2006-01-01
Considering connections of characteristics,this paper is aimed at the construction of optimized Boolean functions.A new method based on the Bent function,discrete Walsh spectrum and characteristics matrices are presented by concatenating,breaking,and revising output sequences conditionally.This new construction can be used to construct different kinds of functions satisfying different design criteria.
Staircase and Fractional Part Functions
Amram, Meirav; Dagan, Miriam; Ioshpe, Michael; Satianov, Pavel
2016-01-01
The staircase and fractional part functions are basic examples of real functions. They can be applied in several parts of mathematics, such as analysis, number theory, formulas for primes, and so on; in computer programming, the floor and ceiling functions are provided by a significant number of programming languages--they have some basic uses in…
Proposals for iterated hash functions
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Thomsen, Søren Steffen
2006-01-01
The past few years have seen an increase in the number of attacks on cryptographic hash functions. These include attacks directed at specific hash functions, and generic attacks on the typical method of constructing hash functions. In this paper we discuss possible methods for protecting against...... some generic attacks. We also give a concrete proposal for a new hash function construction, given a secure compression function which, unlike in typical existing constructions, is not required to be resistant to all types of collisions. Finally, we show how members of the SHA-family can be turned...
Proposals for Iterated Hash Functions
DEFF Research Database (Denmark)
Knudsen, Lars Ramkilde; Thomsen, Søren Steffen
2008-01-01
The past few years have seen an increase in the number of attacks on cryptographic hash functions. These include attacks directed at specific hash functions, and generic attacks on the typical method of constructing hash functions. In this paper we discuss possible methods for protecting against...... some generic attacks. We also give a concrete proposal for a new hash function construction, given a secure compression function which, unlike in typical existing constructions, is not required to be resistant to all types of collisions. Finally, we show how members of the SHA-family can be turned...
Banach spaces of analytic functions
Hoffman, Kenneth
2007-01-01
A classic of pure mathematics, this advanced graduate-level text explores the intersection of functional analysis and analytic function theory. Close in spirit to abstract harmonic analysis, it is confined to Banach spaces of analytic functions in the unit disc.The author devotes the first four chapters to proofs of classical theorems on boundary values and boundary integral representations of analytic functions in the unit disc, including generalizations to Dirichlet algebras. The fifth chapter contains the factorization theory of Hp functions, a discussion of some partial extensions of the f
Nongenetic functions of the genome.
Bustin, Michael; Misteli, Tom
2016-05-01
The primary function of the genome is to store, propagate, and express the genetic information that gives rise to a cell's architectural and functional machinery. However, the genome is also a major structural component of the cell. Besides its genetic roles, the genome affects cellular functions by nongenetic means through its physical and structural properties, particularly by exerting mechanical forces and by serving as a scaffold for binding of cellular components. Major cellular processes affected by nongenetic functions of the genome include establishment of nuclear structure, signal transduction, mechanoresponses, cell migration, and vision in nocturnal animals. We discuss the concept, mechanisms, and implications of nongenetic functions of the genome.
Density Functional Approach Based on Numerically Obtained Bridge Functional
Institute of Scientific and Technical Information of China (English)
ZHOUShi－Qi
2002-01-01
The ornstein-zenike equation is solved with the Rogers-Young approximation for bulk hard sphere fluid and Lennard-Jones fluid for several state points.Then the resulted bulk fluid radial distribution function combined with the test particle method is employed to determine numerically the function relationship of bridge functional as a function of indirect correlation function.It is found that all of the calculated points from different phase space state points for a same type of fluid collapse onto a same smooth curve.Then the numerically obtained curve is used to substitute the analytic expression of the bridge functional as a function of indirect correlation function required in the methodology [J.Chem.Phys,112(2000)8079] to determine the density distribution of non-uniform hard sphere fluid and Lennard-Jones fluid.The good agreement of theoretical predictions with the computer simulation data is obtained.The present numerical procedure incroporates the knowledge of bulk fluid radial distribution function into the constructing of the density functional approximation and makes the original methodology more accurate and more filexible for various interaction potential fluid.
Bilinear Expansion For Redistribution Functions
Harutyunian, Haik; Alecian, Georges; Khachatryan, Knarik; Vardanyan, Ani
2016-11-01
We suggest here a method for construction of a bilinear expansion for an angle-averaged redistribution function. This function describes the elementary act of a photon scattering by a model two-level atom with the upper level broadened due to radiation damping. An eigenvalue and eigenvector determination problem is formulated and the relevant matrices are found analytically. Numerical procedures for their computations are elaborated as well. A simple method for the numerical calculations accuracy evaluation is suggested. It is shown that a family of redistribution functions describing the light scattering process within the spectral line frequencies can be constructed if the eigenvalue problem for the considered function is solved. It becomes possible if the eigenvalues and eigenvectors with the appropriate basic functions are used. The Voigt function and its derivatives used as basic functions are studied in detail as well.
On hash functions using checksums
DEFF Research Database (Denmark)
Gauravaram, Praveen; Kelsey, John; Knudsen, Lars Ramkilde;
2010-01-01
We analyse the security of iterated hash functions that compute an input dependent checksum which is processed as part of the hash computation. We show that a large class of such schemes, including those using non-linear or even one-way checksum functions, is not secure against the second preimage...... attack of Kelsey and Schneier, the herding attack of Kelsey and Kohno and the multicollision attack of Joux. Our attacks also apply to a large class of cascaded hash functions. Our second preimage attacks on the cascaded hash functions improve the results of Joux presented at Crypto'04. We also apply our...... attacks to the MD2 and GOST hash functions. Our second preimage attacks on the MD2 and GOST hash functions improve the previous best known short-cut second preimage attacks on these hash functions by factors of at least 226 and 254, respectively. Our herding and multicollision attacks on the hash...
Functional Programming in Computer Science
Energy Technology Data Exchange (ETDEWEB)
Anderson, Loren James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Davis, Marion Kei [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
2016-01-19
We explore functional programming through a 16-week internship at Los Alamos National Laboratory. Functional programming is a branch of computer science that has exploded in popularity over the past decade due to its high-level syntax, ease of parallelization, and abundant applications. First, we summarize functional programming by listing the advantages of functional programming languages over the usual imperative languages, and we introduce the concept of parsing. Second, we discuss the importance of lambda calculus in the theory of functional programming. Lambda calculus was invented by Alonzo Church in the 1930s to formalize the concept of effective computability, and every functional language is essentially some implementation of lambda calculus. Finally, we display the lasting products of the internship: additions to a compiler and runtime system for the pure functional language STG, including both a set of tests that indicate the validity of updates to the compiler and a compiler pass that checks for illegal instances of duplicate names.
Generalizing Single Variable Functions to Two-Variable Functions, Function Machine and APOS
Kabael, Tangul Uygur
2011-01-01
The focus of this study in which the theoretical framework of APOS was used is students' generalizing function notion from single variable to two-variable function concepts in Analysis II course in the elementary mathematics education program. In the teaching process, teaching activities that support generalizing the function notion with multiple…
Radial basis function networks and complexity regularization in function learning.
Krzyzak, A; Linder, T
1998-01-01
In this paper we apply the method of complexity regularization to derive estimation bounds for nonlinear function estimation using a single hidden layer radial basis function network. Our approach differs from previous complexity regularization neural-network function learning schemes in that we operate with random covering numbers and l(1) metric entropy, making it possible to consider much broader families of activation functions, namely functions of bounded variation. Some constraints previously imposed on the network parameters are also eliminated this way. The network is trained by means of complexity regularization involving empirical risk minimization. Bounds on the expected risk in terms of the sample size are obtained for a large class of loss functions. Rates of convergence to the optimal loss are also derived.
Family of Subharmonic Functions and Separately Subharmonic Functions
Kalantar, Mansour
2016-01-01
We prove that a separately subharmonic function is subharmonic outside a closed set whose projections are closed nowhere dense with no bounded components. It generalizes a result due to U. Cegerell and A. Sadullaev. Then, given such a set, we construct a separately subharmonic function that is subharmonic everywhere outside that set. We start by proving similar results for the supremum of a family of subharmonic functions that is finite everywhere.
Function Analysis and Decomposistion using Function Analysis Systems Technique
Energy Technology Data Exchange (ETDEWEB)
Wixson, James Robert
1999-06-01
The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Technique (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.
Function Analysis and Decomposistion using Function Analysis Systems Technique
Energy Technology Data Exchange (ETDEWEB)
J. R. Wixson
1999-06-01
The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Techniques (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.
Cell functional enviromics: Unravelling the function of environmental factors
Directory of Open Access Journals (Sweden)
Alves Paula M
2011-06-01
Full Text Available Abstract Background While functional genomics, focused on gene functions and gene-gene interactions, has become a very active field of research in molecular biology, equivalent methodologies embracing the environment and gene-environment interactions are relatively less developed. Understanding the function of environmental factors is, however, of paramount importance given the complex, interactive nature of environmental and genetic factors across multiple time scales. Results Here, we propose a systems biology framework, where the function of environmental factors is set at its core. We set forth a "reverse" functional analysis approach, whereby cellular functions are reconstructed from the analysis of dynamic envirome data. Our results show these data sets can be mapped to less than 20 core cellular functions in a typical mammalian cell culture, while explaining over 90% of flux data variance. A functional enviromics map can be created, which provides a template for manipulating the environmental factors to induce a desired phenotypic trait. Conclusion Our results support the feasibility of cellular function reconstruction guided by the analysis and manipulation of dynamic envirome data.
Self stigmatization, cognitive functions and social functioning in mood disorders
Directory of Open Access Journals (Sweden)
Gulsum Ozge Doganavsargil Baysal
2013-06-01
Full Text Available Purpose: Internalized stigmatization (IS generally has a negative effect on diagnosis, treatment, rehabilitation and prognosis of diseases. The purpose of this study is to compare patients with bipolar disorder and unipolar depression both are in remission in terms of IS and social functioning (SF, cognitive function and secondly to consider relationship between IS, cognitive functions and SF. Methods: This cross-sectional study is carried out with bipolar (BD and unipolar depression (UD patients in remission, admitted to the psychiatry outpatient clinics of Akdeniz University Hospital. The sample size is estimated as 35 patients. Basic independent variable is the type of disease and dependent variables are; IS, cognitive functions and SF. Performed scales are: The internalized stigma of mental ilness scale, the social functioning scale and for the assesment of cognitive functions: Wisconsin card sorting, stroop test, test of verbal memory process. Results.Concerning the results there was negative corelation between IS and SF scores in all groups. There was only significant relationship between verbal memory and IS in UD patients. There was not any significant relationship between IS and cognitive function in BD patients. Conclusion: This study indicates that in terms of cognitive functions, patients with unipolar depression are effected as much as the patients with bipolar disorder also manifesting the inverse relation between IS and SF, however cognitive functions were relevant to IS only in UD patients. [Cukurova Med J 2013; 38(3.000: 390-402
Density Functional Approach Based on Numerically Obtained Bridge Functional
Institute of Scientific and Technical Information of China (English)
ZHOU Shi-Qi
2002-01-01
The Ornstein Zernike equation is solved with the Rogers Young approximation for bulk hard sphere fluidand Lennard-Jones fluid for several state points. Then the resulted bulk fluid radial distribution function combinedwith the test particle method is employed to determine numerically the function relationship of bridge functional as afunction of indirect correlation function. It is found that all of the calculated points from different phase space statepoints for a same type of fluid collapse onto a same smooth curve. Then the numerically obtained curve is used tosubstitute the analytic expression of the bridge functional as a function of indirect correlation function required in themethodology [J. Chem. Phys. 112 (2000) 8079] to deterrnine the density distribution of non-uniform hard spherefluid and Lennard Jones fluid. The good agreement of theoretical predictions with the computer simulation data isobtained. The present numerical procedure incorporates the knowledge of bulk fluid radial distribution function intothe constructing of the density functional approximation and makes the original methodology more accurate and moreflexible for various interaction potential fluid.
CHARACTERISTIC OF COMPOSITION MEROMORPHIC FUNCTIONS WITH DEFICIENT FUNCTIONS
Institute of Scientific and Technical Information of China (English)
SUN Jian-wu
2004-01-01
In this paper, we obtain the following result: Let f(z) be a meromorphic function of order ρ and lower order λ , let ai (z) ( I = 1,2,… n, n ≤ ∞ ) be entire function, which satisying T( r, ai (z) = o ( T( r ,f) ) with ∑ni=1δ(ai(z),f) = 1 andδ(ai(z),f) ＞ 0 (ai(z) (≠)∞).If lim T r→∞( r,f(z + 1))/ T(r,f(z)) = ∞.Then ρ=λ= ∞.We solved problem due to C. C. Yang concerning the characteristic functions of the composite functions.
Transfer Function Identification Using Orthogonal Fourier Transform Modeling Functions
Morelli, Eugene A.
2013-01-01
A method for transfer function identification, including both model structure determination and parameter estimation, was developed and demonstrated. The approach uses orthogonal modeling functions generated from frequency domain data obtained by Fourier transformation of time series data. The method was applied to simulation data to identify continuous-time transfer function models and unsteady aerodynamic models. Model fit error, estimated model parameters, and the associated uncertainties were used to show the effectiveness of the method for identifying accurate transfer function models from noisy data.
Staircase and fractional part functions
Amram, Meirav; Dagan, Miriam; Ioshpe, Michael; Satianov, Pavel
2016-10-01
The staircase and fractional part functions are basic examples of real functions. They can be applied in several parts of mathematics, such as analysis, number theory, formulas for primes, and so on; in computer programming, the floor and ceiling functions are provided by a significant number of programming languages - they have some basic uses in various programming tasks. In this paper, we view the staircase and fractional part functions as a classical example of non-continuous real functions. We introduce some of their basic properties, present some interesting constructions concerning them, and explore some intriguing interpretations of such functions. Throughout the paper, we use these functions in order to explain basic concepts in a first calculus course, such as domain of definition, discontinuity, and oddness of functions. We also explain in detail how, after researching the properties of such functions, one can draw their graph; this is a crucial part in the process of understanding their nature. In the paper, we present some subjects that the first-year student in the exact sciences may not encounter. We try to clarify those subjects and show that such ideas are important in the understanding of non-continuous functions, as a part of studying analysis in general.
BROKEN LINES SIGNALS AND SMARANDACHE STEPPED FUNCTIONS
Şelariu, Mircea
2012-01-01
The evolutive supermathematical functions (FSM ─ Ev) are discussed in the papers [1], [2], [3], [4], [5], [6], [7], [8]. They are combinations of the four types of FSM (centric functions (FC), excentric functions (FE), elevated functions (FEl) and exotic functions (FEx), taken by two, called centricoexcentric functions, elevatoexotic functions, centricoelevated functions, and so forth).
Functional annotation of hierarchical modularity.
Directory of Open Access Journals (Sweden)
Kanchana Padmanabhan
Full Text Available In biological networks of molecular interactions in a cell, network motifs that are biologically relevant are also functionally coherent, or form functional modules. These functionally coherent modules combine in a hierarchical manner into larger, less cohesive subsystems, thus revealing one of the essential design principles of system-level cellular organization and function-hierarchical modularity. Arguably, hierarchical modularity has not been explicitly taken into consideration by most, if not all, functional annotation systems. As a result, the existing methods would often fail to assign a statistically significant functional coherence score to biologically relevant molecular machines. We developed a methodology for hierarchical functional annotation. Given the hierarchical taxonomy of functional concepts (e.g., Gene Ontology and the association of individual genes or proteins with these concepts (e.g., GO terms, our method will assign a Hierarchical Modularity Score (HMS to each node in the hierarchy of functional modules; the HMS score and its p-value measure functional coherence of each module in the hierarchy. While existing methods annotate each module with a set of "enriched" functional terms in a bag of genes, our complementary method provides the hierarchical functional annotation of the modules and their hierarchically organized components. A hierarchical organization of functional modules often comes as a bi-product of cluster analysis of gene expression data or protein interaction data. Otherwise, our method will automatically build such a hierarchy by directly incorporating the functional taxonomy information into the hierarchy search process and by allowing multi-functional genes to be part of more than one component in the hierarchy. In addition, its underlying HMS scoring metric ensures that functional specificity of the terms across different levels of the hierarchical taxonomy is properly treated. We have evaluated our
Interpolating function and Stokes Phenomena
Honda, Masazumi
2015-01-01
When we have two expansions of physical quantity around two different points in parameter space, we can usually construct a family of functions, which interpolates the both expansions. In this paper we study analytic structures of such interpolating functions and discuss their physical implications. We propose that the analytic structures of the interpolating functions provide information on analytic property and Stokes phenomena of the physical quantity, which we approximate by the interpolating functions. We explicitly check our proposal for partition functions of zero-dimensional $\\varphi^4$ theory and Sine-Gordon model. In the zero dimensional Sine-Gordon model, we compare our result with a recent result from resurgence analysis. We also comment on construction of interpolating function in Borel plane.
An introduction to special functions
Viola, Carlo
2016-01-01
The subjects treated in this book have been especially chosen to represent a bridge connecting the content of a first course on the elementary theory of analytic functions with a rigorous treatment of some of the most important special functions: the Euler gamma function, the Gauss hypergeometric function, and the Kummer confluent hypergeometric function. Such special functions are indispensable tools in "higher calculus" and are frequently encountered in almost all branches of pure and applied mathematics. The only knowledge assumed on the part of the reader is an understanding of basic concepts to the level of an elementary course covering the residue theorem, Cauchy's integral formula, the Taylor and Laurent series expansions, poles and essential singularities, branch points, etc. The book addresses the needs of advanced undergraduate and graduate students in mathematics or physics.
Markers of renal function tests
Directory of Open Access Journals (Sweden)
Shivaraj Gowda
2010-04-01
Full Text Available Background: The markers of renal function test assess the normal functioning of kidneys. These markers may be radioactive and non radioactive. They indicate the glomerular filtration rate, concentrating and diluting capacity of kidneys (tubular function. If there is an increase or decrease in the valves of these markers it indicates dysfunction of kidney. Aim: The aim of this review is to compare and analyze the present and newer markers of renal function tests which help in diagnosis of clinical disorders. Material & Methods: An extensive literature survey was done aiming to compare and compile renal function tests makers required in diagnosis of diseases. Results: Creatinine, urea, uric acid and electrolytes are makers for routine analysis whereas several studies have confirmed and consolidated the usefulness of markers such as cystatin C and β-Trace Protein. Conclusion: We conclude that further investigation is necessary to define these biomarkers in terms of usefulness in assessing renal function.
Curvature function and coarse graining
Diaz-Marin, Homero G; 10.1063/1.3521553
2011-01-01
A classic theorem in the theory of connections on principal fiber bundles states that the evaluation of all holonomy functions gives enough information to characterize the bundle structure (among those sharing the same structure group and base manifold) and the connection up to a bundle equivalence map. This result and other important properties of holonomy functions has encouraged their use as the primary ingredient for the construction of families of quantum gauge theories. However, in these applications often the set of holonomy functions used is a discrete proper subset of the set of holonomy functions needed for the characterization theorem to hold. We show that the evaluation of a discrete set of holonomy functions does not characterize the bundle and does not constrain the connection modulo gauge appropriately. We exhibit a discrete set of functions of the connection and prove that in the abelian case their evaluation characterizes the bundle structure (up to equivalence), and constrains the connection...
Biomolecule-functionalized polymer brushes.
Jiang, Hui; Xu, Fu-Jian
2013-04-21
Functional polymer brushes have been utilized extensively for the immobilization of biomolecules, which is of crucial importance for the development of biosensors and biotechnology. Recent progress in polymerization methods, in particular surface-initiated atom transfer radical polymerization (ATRP), has provided a unique means for the design and synthesis of new biomolecule-functionalized polymer brushes. This current review summarizes such recent research activities. The different preparation strategies for biomolecule immobilization through polymer brush spacers are described in detail. The functional groups of the polymer brushes used for biomolecule immobilization include epoxide, carboxylic acid, hydroxyl, aldehyde, and amine groups. The recent research activities indicate that functional polymer brushes become versatile and powerful spacers for immobilization of various biomolecules to maximize their functionalities. This review also demonstrates that surface-initiated ATRP is used more frequently than other polymerization methods in the designs of new biomolecule-functionalized polymer brushes.
CMAC with General Basis Functions.
Chun-Shin, Lin; Ching-Tsan, Chiang
1996-10-01
The cerebellar model articulation controller (CMAC) is often used in learning control. It can be viewed as a basis function network (BFN). The conventional CMAC uses local constant basis functions. A disadvantage is that its output is constant within each quantized state and the derivative information is not preserved. If the constant basis functions are replaced by non-constant differentiable basis functions, the derivative information will be able to be stored into the structure as well. In this paper, the generalized scheme that uses general basis functions is investigated. The conventional CMAC is a special case of the generalized technique. The mathematical foundation for the modified scheme is derived and the convergence of learning is proved. Simulations for the CMAC with Gaussian basis functions (GBFs) are performed to demonstrate the improvement of accuracy in modeling, and the capability in providing derivative information. Copyright 1996 Elsevier Science Ltd
Mechanics of advanced functional materials
Wang, Biao
2013-01-01
Mechanics of Advanced Functional Materials emphasizes the coupling effect between the electric and mechanical field in the piezoelectric, ferroelectric and other functional materials. It also discusses the size effect on the ferroelectric domain instability and phase transition behaviors using the continuum micro-structural evolution models. Functional materials usually have a very wide application in engineering due to their unique thermal, electric, magnetic, optoelectronic, etc., functions. Almost all the applications demand that the material should have reasonable stiffness, strength, fracture toughness and the other mechanical properties. Furthermore, usually the stress and strain fields on the functional materials and devices have some important coupling effect on the functionality of the materials. Much progress has been made concerning the coupling electric and mechanical behaviors such as the coupled electric and stress field distribution in piezoelectric solids, ferroelectric domain patterns in ferr...
The relativity of biological function.
Laubichler, Manfred D; Stadler, Peter F; Prohaska, Sonja J; Nowick, Katja
2015-12-01
Function is a central concept in biological theories and explanations. Yet discussions about function are often based on a narrow understanding of biological systems and processes, such as idealized molecular systems or simple evolutionary, i.e., selective, dynamics. Conflicting conceptions of function continue to be used in the scientific literature to support certain claims, for instance about the fraction of "functional DNA" in the human genome. Here we argue that all biologically meaningful interpretations of function are necessarily context dependent. This implies that they derive their meaning as well as their range of applicability only within a specific theoretical and measurement context. We use this framework to shed light on the current debate about functional DNA and argue that without considering explicitly the theoretical and measurement contexts all attempts to integrate biological theories are prone to fail.
Probabilistic aspects of Wigner function
Usenko, C V
2004-01-01
The Wigner function of quantum systems is an effective instrument to construct the approximate classical description of the systems for which the classical approximation is possible. During the last time, the Wigner function formalism is applied as well to seek indications of specific quantum properties of quantum systems leading to impossibility of the classical approximation construction. Most of all, as such an indication the existence of negative values in Wigner function for specific states of the quantum system being studied is used. The existence of such values itself prejudices the probabilistic interpretation of the Wigner function, though for an arbitrary observable depending jointly on the coordinate and the momentum of the quantum system just the Wigner function gives an effective instrument to calculate the average value and the other statistical characteristics. In this paper probabilistic interpretation of the Wigner function based on coordination of theoretical-probabilistic definition of the ...
Optimality Functions and Lopsided Convergence
2015-03-16
Problems involving functions defined in terms of integrals or optimization problems (as the maxi - mization in Example 3), functions defined on infinite...optimization methods in finite time. The key technical challenge associate with the above scheme is to establish ( weak ) consistency. In the next...Theorem 4.3. In view of this result, it is clear that ( weak ) consistency will be ensured by epi-convergence of the approximating objective functions and
On functions of bounded variation
Aistleitner, Christoph; Pausinger, Florian; Svane, Anne Marie; Tichy, Robert F.
2015-01-01
The recently introduced concept of $\\mathcal{D}$-variation unifies previous concepts of variation of multivariate functions. In this paper, we give an affirmative answer to the open question from Pausinger \\& Svane (J. Complexity, 2014) whether every function of bounded Hardy--Krause variation is Borel measurable and has bounded $\\mathcal{D}$-variation. Moreover, we show that the space of functions of bounded $\\mathcal{D}$-variation can be turned into a commutative Banach algebra.
Allaart, Pieter
2011-01-01
This paper sketches the history of the Takagi function T and surveys known properties of T, including its nowhere-differentiability, modulus of continuity, graphical properties and level sets. Several generalizations of the Takagi function, in as far as they are based on the "tent map", are also discussed. The final section reviews a number of applications of the Takagi function to various areas of mathematics, including number theory, combinatorics and classical real analysis.
Reliable Function Approximation and Estimation
2016-08-16
AFRL-AFOSR-VA-TR-2016-0293 Reliable Function Approximation and Estimation Rachel Ward UNIVERSITY OF TEXAS AT AUSTIN 101 EAST 27TH STREET STE 4308...orthogonal polynomial bases from a minimal number of pointwise function evaluations. Based on a model of weighted sparsity which we in- troduced, we...Institution name University of Texas at Austin Grant/Contract Title The full title of the funded effort. (YIP): Reliable function approximation and estimation
Complement Activation Alters Platelet Function
2015-12-01
Award Number: W81XWH-12-1-0523 TITLE: Complement Activation Alters Platelet Function PRINCIPAL INVESTIGATOR: George Tsokos, M.D. CONTRACTING...Activation Alters Platelet Function 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-12-1-0523 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) George Tsokos, M.D...a decreased level of disease. Further studies will expand upon these observations better outlining the function of platelets in the injury associated
Dansk skepsis mod "functional foods"
DEFF Research Database (Denmark)
Bech-Larsen, Tino
2000-01-01
MAPP Centret har undersøgt danske, finske og amerikanske forbrugeres holdninger til functional foods og til genmodificerede fødevarer. Undersøgelsen er baseret på personlige interviews med 1500 danske, finske og nordamerikanske forbrugere. På trods af den store udbredelse af functional foods i USA......, viste undersøgelsen, at finnerne faktisk var mere positive over for functional foods end amerikanerne. De danske forbrugere var klart de mest skeptiske....
Bilateral zeta functions and their applications
Shibukawa, Genki
2011-01-01
We introduce a new type of multiple zeta functions, which we call bilateral zeta functions, analogous to the Barnes zeta functions. The bilateral zeta function is a periodic function and shares certain basic properties of Barnes zeta function. Especially, we prove that the bilateral zeta function has a nice Fourier series expansion and the Barnes zeta function can be expressed as a finite sum of bilateral zeta functions. By these properties of the bilateral zeta functions, We obtain simple pr...
Iterated Function Systems on Functions of Bounded Variation
La Torre, Davide; Mendivil, Franklin; Vrscay, Edward R.
2016-04-01
We show that under certain hypotheses, an iterated function system on mappings (IFSM) is a contraction on the complete space of functions of bounded variation (BV). It then possesses a unique attractor of BV. Some BV-based inverse problems based on the Collage Theorem for contraction maps are considered.
Derivatives of Meromorphic functions with multiple zeros and elliptic functions
Yang, Pai; Pang, Xuecheng
2011-01-01
Let f be a nonconstant meromorphic function in the plane and h be a nonconstant elliptic function. We show that if all zeros of f are multiple exept finitely many and T(r,h)=o{T(r,f)} as r tends to infinity, then f'=h has infinitely many solutions (including poles).
The Relationship between Mathematical Induction, Proposition Functions, and Implication Functions
Andrew, Lane
2010-01-01
In this study, I explored the relationship between mathematical induction ability and proposition and implication functions through a mixed methods approach. Students from three universities (N = 78) and 6 classrooms completed a written assessment testing their conceptual and procedural capabilities with induction and functions. In addition, I…
Functional model realizations for Schur functions on C+
Kurula, Mikael; Ball, Joseph A.; Staffans, Olof J.; Zwart, Hans
2014-01-01
For an arbitrary given operator Schur function defined on the complex right-half plane, we give a controllable energy-preserving and an observable co-energy-preserving de Branges-Rovnyak functional model realization. Topics appearing only in the right-half-plane setting, such as the extrapolation sp
Prestarlike functions with negative coefficients
Directory of Open Access Journals (Sweden)
H. Silverman
1979-01-01
Full Text Available The extreme points for prestarlike functions having negative coefficients are determined. Coefficient, distortion and radii of univalence, starlikeness, and convexity theorems are also obtained.
Localized functionalization of single nanopores
Energy Technology Data Exchange (ETDEWEB)
Nilsson, J; Lee, J I; Ratto, T V; Letant, S E
2005-09-12
We demonstrate the localization of chemical functionality at the entrance of single nanopores for the first time by using the controlled growth of an oxide ring. Nanopores were fabricated by Focused Ion Beam machining on silicon platforms, locally derivatized by ion beam assisted oxide deposition, and further functionalized with DNA probes via silane chemistry. Ionic current recorded through single nanopores at various stages of the fabrication process demonstrated that the apertures can be locally functionalized with DNA probes. Future applications for this functional platform include the selective detection of biological organisms and molecules by ionic current blockade measurements.
Center for Functional Nanomaterials (CFN)
Federal Laboratory Consortium — The CFN at Brookhaven National Laboratory focuses on understanding the chemical and physical response of nanomaterials to make functional materials such as sensors,...
Value Distribution of Meromorphic Functions
Zheng, Jianhua
2011-01-01
"Value Distribution of Meromorphic Functions" focuses on functions meromorphic in an angle or on the complex plane, T directions, deficient values, singular values, potential theory in value distribution and the proof of the celebrated Nevanlinna conjecture. The book introduces various characteristics of meromorphic functions and their connections, several aspects of new singular directions, new results on estimates of the number of deficient values, new results on singular values and behaviours of subharmonic functions which are the foundation for further discussion on the proof of
DEFF Research Database (Denmark)
Dahl, Jens Peder; Varro, S.; Wolf, A.
2007-01-01
We derive explicit expressions for the Wigner function of wave functions in D dimensions which depend on the hyperradius-that is, of s waves. They are based either on the position or the momentum representation of the s wave. The corresponding Wigner function depends on three variables......: the absolute value of the D-dimensional position and momentum vectors and the angle between them. We illustrate these expressions by calculating and discussing the Wigner functions of an elementary s wave and the energy eigenfunction of a free particle....
Communication Complexities of XOR functions
Shi, Yaoyun; Zhang,Zhiqiang
2008-01-01
We call $F:\\{0, 1\\}^n\\times \\{0, 1\\}^n\\to\\{0, 1\\}$ a symmetric XOR function if for a function $S:\\{0, 1, ..., n\\}\\to\\{0, 1\\}$, $F(x, y)=S(|x\\oplus y|)$, for any $x, y\\in\\{0, 1\\}^n$, where $|x\\oplus y|$ is the Hamming weight of the bit-wise XOR of $x$ and $y$. We show that for any such function, (a) the deterministic communication complexity is always $\\Theta(n)$ except for four simple functions that have a constant complexity, and (b) up to a polylog factor, the error-bounded randomized and q...
Harmonic functions with varying coefficients
Directory of Open Access Journals (Sweden)
Jacek Dziok
2016-05-01
Full Text Available Abstract Complex-valued harmonic functions that are univalent and sense preserving in the open unit disk can be written in the form f = h + g ‾ $f=h+\\overline{g}$ , where h and g are analytic. In this paper we investigate some classes of univalent harmonic functions with varying coefficients related to Janowski functions. By using the extreme points theory we obtain necessary and sufficient convolution conditions, coefficients estimates, distortion theorems, and integral mean inequalities for these classes of functions. The radii of starlikeness and convexity for these classes are also determined.
Generalized functionals of Brownian motion
Directory of Open Access Journals (Sweden)
N. U. Ahmed
1994-01-01
Full Text Available In this paper we discuss some recent developments in the theory of generalized functionals of Brownian motion. First we give a brief summary of the Wiener-Ito multiple Integrals. We discuss some of their basic properties, and related functional analysis on Wiener measure space. then we discuss the generalized functionals constructed by Hida. The generalized functionals of Hida are based on L2-Sobolev spaces, thereby, admitting only Hs, s∈R valued kernels in the multiple stochastic integrals. These functionals are much more general than the classical Wiener-Ito class. The more recent development, due to the author, introduces a much more broad class of generalized functionals which are based on Lp-Sobolev spaces admitting kernels from the spaces p,s, s∈R. This allows analysis of a very broad class of nonlinear functionals of Brownian motion, which can not be handled by either the Wiener-Ito class or the Hida class. For s≤0, they represent generalized functionals on the Wiener measure space like Schwarz distributions on finite dimensional spaces. In this paper we also introduce some further generalizations, and construct a locally convex topological vector space of generalized functionals. We also present some discussion on the applications of these results.
Television and children's executive function.
Lillard, Angeline S; Li, Hui; Boguszewski, Katie
2015-01-01
Children spend a lot of time watching television on its many platforms: directly, online, and via videos and DVDs. Many researchers are concerned that some types of television content appear to negatively influence children's executive function. Because (1) executive function predicts key developmental outcomes, (2) executive function appears to be influenced by some television content, and (3) American children watch large quantities of television (including the content of concern), the issues discussed here comprise a crucial public health issue. Further research is needed to reveal exactly what television content is implicated, what underlies television's effect on executive function, how long the effect lasts, and who is affected.
Molecular calculations with B functions
Steinborn, E O; Ema, I; López, R; Ramírez, G
1998-01-01
A program for molecular calculations with B functions is reported and its performance is analyzed. All the one- and two-center integrals, and the three-center nuclear attraction integrals are computed by direct procedures, using previously developed algorithms. The three- and four-center electron repulsion integrals are computed by means of Gaussian expansions of the B functions. A new procedure for obtaining these expansions is also reported. Some results on full molecular calculations are included to show the capabilities of the program and the quality of the B functions to represent the electronic functions in molecules.
A deterministic width function model
Directory of Open Access Journals (Sweden)
C. E. Puente
2003-01-01
Full Text Available Use of a deterministic fractal-multifractal (FM geometric method to model width functions of natural river networks, as derived distributions of simple multifractal measures via fractal interpolating functions, is reported. It is first demonstrated that the FM procedure may be used to simulate natural width functions, preserving their most relevant features like their overall shape and texture and their observed power-law scaling on their power spectra. It is then shown, via two natural river networks (Racoon and Brushy creeks in the United States, that the FM approach may also be used to closely approximate existing width functions.
Pakeman, Robin J; Stockan, Jenni A
2014-05-01
Understanding how community assembly is controlled by the balance of abiotic drivers (environment or management) and biotic drivers (community composition of other groups) is important in predicting the response of ecosystems to environmental change. If there are strong links between plant assemblage structure and carabid beetle functional traits and functional diversity, then it is possible to predict the impact of environmental change propagating through different functional and trophic groups. Vegetation and pitfall trap beetle surveys were carried out across twenty four sites contrasting in land use, and hence productivity and disturbance regime. Plant functional traits were very successful at explaining the distribution of carabid functional traits across the habitats studied. Key carabid response traits appeared to be body length and wing type. Carabid functional richness was significantly smaller than expected, indicating strong environmental filtering, modulated by management, soil characteristics, and by plant response traits. Carabid functional divergence was negatively related to plant functional evenness, while carabid functional evenness was positively correlated to plant functional evenness and richness. The study shows that there are clear trait linkages between the plant and the carabid assemblage that act not only through the mean traits displayed, but also via their distribution in trait space; powerful evidence that both the mean and variance of traits in one trophic group structure the assemblage of another.
O'Rourke, Norm; King, David B; Cappeliez, Philippe
2017-03-01
The current study examines the temporal stability of the tripartite model of reminiscence functions in which eight separate reminiscence functions map onto three second-order factors which contribute significantly to measurement of an overarching reminiscence latent construct. We collected online responses from 411 adults 50+ years of age. Confirmatory factor analytic models were computed at three points of data collection over 16 months. Invariance analyses were next undertaken to simultaneously compare the measurement properties to assess within-person stability of reminiscence functions over time. The tripartite structure of reminiscence functions was replicated at each point of data collection. As hypothesised, self-positive and self-negative functions are consistent across points of data collection, whereas prosocial functions vary over time. The temporal stability of the self functions may be attributed to enduring characteristics of the individual such as personality traits and life attitudes, as well as their solitary nature. Previous research indicates that consistency of self-positive reminiscence functions has ensuing benefits for physical health and psychological well-being; the opposite is true for self-negative functions. The temporal variation of prosocial functions may be due to the varying availability of others to share memories and their responsiveness to the emotional context.
Technical Rebuilding of Movement Function Using Functional Electrical Stimulation
Gföhler, Margit
To rebuild lost movement functions, neuroprostheses based on functional electrical stimulation (FES) artificially activate skeletal muscles in corresponding sequences, using both residual body functions and artificial signals for control. Besides the functional gain, FES training also brings physiological and psychological benefits for spinal cord-injured subjects. In this chapter, current stimulation technology and the main components of FES-based neuroprostheses including enhanced control systems are presented. Technology and application of FES cycling and rowing, both approaches that enable spinal cord-injured subjects to participate in mainstream activities and improve their health and fitness by exercising like able-bodied subjects, are discussed in detail, and an overview of neuroprostheses that aim at restoring movement functions for daily life as walking or grasping is given.
Density Functionals of Chemical Bonding
Directory of Open Access Journals (Sweden)
Mihai V. Putz
2008-06-01
Full Text Available The behavior of electrons in general many-electronic systems throughout the density functionals of energy is reviewed. The basic physico-chemical concepts of density functional theory are employed to highlight the energy role in chemical structure while its extended influence in electronic localization function helps in chemical bonding understanding. In this context the energy functionals accompanied by electronic localization functions may provide a comprehensive description of the global-local levels electronic structures in general and of chemical bonds in special. Becke-Edgecombe and authorÃ¢Â€Â™s Markovian electronic localization functions are discussed at atomic, molecular and solid state levels. Then, the analytical survey of the main workable kinetic, exchange, and correlation density functionals within local and gradient density approximations is undertaken. The hierarchy of various energy functionals is formulated by employing both the parabolic and statistical correlation degree of them with the electronegativity and chemical hardness indices by means of quantitative structure-property relationship (QSPR analysis for basic atomic and molecular systems.
Decompositions of cascaded GMW functions
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
In this paper, the inner GMW-type factors of any shifted GMW function are determined. As a consequence, the criterion given in related work of Gong et al. for any two shifted GMW functions to be equal is re-obtained as a special case.
Erectile function after radical prostatectomy
DEFF Research Database (Denmark)
Fode, Mikkel; Frey, Anders; Jakobsen, Henrik;
2016-01-01
OBJECTIVE: The aim of this study was to assess postprostatectomy erectile function compared to preoperative status by subjective patient perception and the abbreviated International Index of Erectile Function (IIEF-5) questionnaire. MATERIALS AND METHODS: The study used data from a prospectively ...
Functions in Biological Kind Classification
Lombrozo, Tania; Rehder, Bob
2012-01-01
Biological traits that serve functions, such as a zebra's coloration (for camouflage) or a kangaroo's tail (for balance), seem to have a special role in conceptual representations for biological kinds. In five experiments, we investigate whether and why functional features are privileged in biological kind classification. Experiment 1…
Pharmacologic Effects on Mitochondrial Function
Cohen, Bruce H.
2010-01-01
The vast majority of energy necessary for cellular function is produced in mitochondria. Free-radical production and apoptosis are other critical mitochondrial functions. The complex structure, electrochemical properties of the inner mitochondrial membrane (IMM), and genetic control from both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) are…
Microencapsulation and functional bioactive foods
Food, the essential unit of human nutrition has been both wholesome and safe through human history ensuring the continuity of the human race. Functionalized foods are the rediscovery of the need to provide all nutrients through foods without adulteration. The functional components of foods include...
Computation of hyperspherical Bessel functions
Tram, Thomas
2013-01-01
In this paper we present a fast and accurate numerical algorithm for the computation of hyperspherical Bessel functions of high order and real arguments. For the hyperspherical Bessel functions of closed type, no stable algorithm existed so far due to the lack of a backwards recurrence. All our algorithms are written in C and are publicly available, see the conclusion for web page.
Developmental Changes in Executive Functioning
Lee, Kerry; Bull, Rebecca; Ho, Ringo M. H.
2013-01-01
Although early studies of executive functioning in children supported Miyake et al.'s (2000) three-factor model, more recent findings supported a variety of undifferentiated or two-factor structures. Using a cohort-sequential design, this study examined whether there were age-related differences in the structure of executive functioning among…
Classification of current scoring functions.
Liu, Jie; Wang, Renxiao
2015-03-23
Scoring functions are a class of computational methods widely applied in structure-based drug design for evaluating protein-ligand interactions. Dozens of scoring functions have been published since the early 1990s. In literature, scoring functions are typically classified as force-field-based, empirical, and knowledge-based. This classification scheme has been quoted for more than a decade and is still repeatedly quoted by some recent publications. Unfortunately, it does not reflect the recent progress in this field. Besides, the naming convention used for describing different types of scoring functions has been somewhat jumbled in literature, which could be confusing for newcomers to this field. Here, we express our viewpoint on an up-to-date classification scheme and appropriate naming convention for current scoring functions. We propose that they can be classified into physics-based methods, empirical scoring functions, knowledge-based potentials, and descriptor-based scoring functions. We also outline the major difference and connections between different categories of scoring functions.
Functional Equations and Fourier Analysis
2010-01-01
By exploring the relations among functional equations, harmonic analysis and representation theory, we give a unified and very accessible approach to solve three important functional equations -- the d'Alembert equation, the Wilson equation, and the d'Alembert long equation, on compact groups.
Weights of Exact Threshold Functions
DEFF Research Database (Denmark)
Babai, László; Hansen, Kristoffer Arnsfelt; Podolskii, Vladimir V.;
2010-01-01
We consider Boolean exact threshold functions defined by linear equations, and in general degree d polynomials. We give upper and lower bounds on the maximum magnitude (absolute value) of the coefficients required to represent such functions. These bounds are very close and in the linear case...
Gordon, Sheldon P.; Gordon, Florence S.
2010-01-01
One of the most important applications of the definite integral in a modern calculus course is the mean value of a function. Thus, if a function "f" is defined on an interval ["a", "b"], then the mean, or average value, of "f" is given by [image omitted]. In this note, we will investigate the meaning of other statistics associated with a function…
Fourier Series and Elliptic Functions
Fay, Temple H.
2003-01-01
Non-linear second-order differential equations whose solutions are the elliptic functions "sn"("t, k"), "cn"("t, k") and "dn"("t, k") are investigated. Using "Mathematica", high precision numerical solutions are generated. From these data, Fourier coefficients are determined yielding approximate formulas for these non-elementary functions that are…
Beta Function and Anomalous Dimensions
DEFF Research Database (Denmark)
Pica, Claudio; Sannino, Francesco
2011-01-01
We demonstrate that it is possible to determine the coefficients of an all-order beta function linear in the anomalous dimensions using as data the two-loop coefficients together with the first one of the anomalous dimensions which are universal. The beta function allows to determine the anomalou...
University Students' Conceptions of Function
Evangelidou, Anastasia; Spyrou, Panayiotis; Elia, Iliada; Gagatsis, Athanasios
2004-01-01
"Function", as it is understood today, formulates one of the most important concepts of mathematics. Nevertheless, many students do not sufficiently understand the abstract but comprehensive meaning of function and problems concerning its didactical metaphor are often confronted. The present study examines the interpretation of the…
The Luminosity Function and Mass Function in the Galactic Bulge
Holtzmann, J A; Baum, W A; Grillmair, C J; Groth, E J; Light, R M; Lynds, R; O'Neil, E J; Holtzman, Jon A.; Watson, Alan M.; Baum, William A.; Grillmair, Carl J.; Groth, Edward J.; Light, Robert M.; Lynds, Roger; Neil, Earl J. O'
1998-01-01
We present deep photometry obtained with the Hubble Space Telescope (HST) in a field in Baade's Window in the Galactic bulge. We derive a luminosity function down to I ~ 24.3, or V ~ 27.5, corresponding to M ~ 0.3 Msun. The luminosity function from the turnoff down to this level appears remarkably similar to that observed in the solar neighborhood. We derive a mass function using both an empirical local mass-luminosity relation and a mass-luminosity relation from recent stellar model calculations, allowing for the presence of binaries and photometric errors. The mass function has a power law form with dN/dM proportional to M^{-2.2} for M >~ 0.7 Msun. However, we find strong evidence for a break in the mass function slope around 0.5-0.7 Msun, with a significantly shallower slope at lower masses. The value of the slope for the low masses depends on the assumed binary fraction and the accuracy of our completeness correction. This mass function should directly reflect the initial mass function.
Hexagon functions and the three-loop remainder function
Energy Technology Data Exchange (ETDEWEB)
Dixon, Lance J.; Drummond, James M.; von Hippel, Matt; Pennington, Jeffrey
2013-12-01
We present the three-loop remainder function, which describes the scattering of six gluons in the maximally-helicity-violating configuration in planar NN = 4 super-Yang-Mills theory, as a function of the three dual conformal cross ratios. The result can be expressed in terms of multiple Goncharov polylogarithms. We also employ a more restricted class of hexagon functions which have the correct branch cuts and certain other restrictions on their symbols. We classify all the hexagon functions through transcendental weight five, using the coproduct for their Hopf algebra iteratively, which amounts to a set of first-order differential equations. The three-loop remainder function is a particular weight-six hexagon function, whose symbol was determined previously. The differential equations can be integrated numerically for generic values of the cross ratios, or analytically in certain kinematic limits, including the near-collinear and multi-Regge limits. These limits allow us to impose constraints from the operator product expansion and multi-Regge factorization directly at the function level, and thereby to fix uniquely a set of Riemann ζ valued constants that could not be fixed at the level of the symbol. The near-collinear limits agree precisely with recent predictions by Basso, Sever and Vieira based on integrability. The multi-Regge limits agree with the factorization formula of Fadin and Lipatov, and determine three constants entering the impact factor at this order. We plot the three-loop remainder function for various slices of the Euclidean region of positive cross ratios, and compare it to the two-loop one. For large ranges of the cross ratios, the ratio of the three-loop to the two-loop remainder function is relatively constant, and close to -7.
Invariant probabilities of transition functions
Zaharopol, Radu
2014-01-01
The structure of the set of all the invariant probabilities and the structure of various types of individual invariant probabilities of a transition function are two topics of significant interest in the theory of transition functions, and are studied in this book. The results obtained are useful in ergodic theory and the theory of dynamical systems, which, in turn, can be applied in various other areas (like number theory). They are illustrated using transition functions defined by flows, semiflows, and one-parameter convolution semigroups of probability measures. In this book, all results on transition probabilities that have been published by the author between 2004 and 2008 are extended to transition functions. The proofs of the results obtained are new. For transition functions that satisfy very general conditions the book describes an ergodic decomposition that provides relevant information on the structure of the corresponding set of invariant probabilities. Ergodic decomposition means a splitting of t...
Elementary functions algorithms and implementation
Muller, Jean-Michel
2016-01-01
This textbook presents the concepts and tools necessary to understand, build, and implement algorithms for computing elementary functions (e.g., logarithms, exponentials, and the trigonometric functions). Both hardware- and software-oriented algorithms are included, along with issues related to accurate floating-point implementation. This third edition has been updated and expanded to incorporate the most recent advances in the field, new elementary function algorithms, and function software. After a preliminary chapter that briefly introduces some fundamental concepts of computer arithmetic, such as floating-point arithmetic and redundant number systems, the text is divided into three main parts. Part I considers the computation of elementary functions using algorithms based on polynomial or rational approximations and using table-based methods; the final chapter in this section deals with basic principles of multiple-precision arithmetic. Part II is devoted to a presentation of “shift-and-add” algorithm...
Occlusal function. Beyond centric relation.
McIntyre, F M; Jureyda, O
2001-01-01
With the emphasis placed on esthetics today, anterior guidance has an important role in the development of a stable, anatomic, functional, and esthetic result. To develop a predictable and stable result requires a multidisciplinary approach to esthetics and function. The orthodontist is a major contributor in helping the restorative dentist achieve the anatomic and functional harmony that is needed for long-term stable function and esthetics. Harmony in function creates long-lasting smiles. In their continued quest for optimal results, and as members of their interdisciplinary teams, orthodontists should remind themselves of what Gottlieb wrote in 1986 in an editorial in the Journal of Clinical Orthodontics: "There is a difference between a beautiful alignment of teeth and an alignment of beautiful teeth. The orthodontist's job is not complete until there is a beautiful alignment of beautiful teeth."
A functional perspective on personality.
Perugini, Marco; Costantini, Giulio; Hughes, Sean; De Houwer, Jan
2016-02-01
Personality psychology has made enormous progresses over the years by accumulating empirical evidence on how patterns of stable individual differences in behaviours can be clustered systematically at different levels of abstraction (i.e. traits and facets) and how they can predict important consequential outcomes. At the same time, functionally orientated researchers have accumulated a vast body of knowledge on environment-behaviour relations and the underlying behavioural principles, that is, abstract descriptions of the way in which behaviour is a function of elements in the past and present environment. We explore a functional perspective on personality that attempts to bridge the two domains and to exploit the best of both worlds. From this functional perspective, personality refers to the impact of the individual on different types of environment-behaviour relations as well as on the way other factors moderate those relations. We discuss the potential of this functional perspective on personality to organise existing scientific knowledge and inspire future research.
Normality Criteria of Meromorphic Functions
Institute of Scientific and Technical Information of China (English)
Wang Qiong; Yuan Wen-jun; Chen Wei; Tian Hong-gen
2016-01-01
In this paper, we consider normality criteria for a family of meromorphic functions concerning shared values. Let F be a family of meromorphic functions defined in a domain D, m, n, k and d be four positive integers satisfying m≥n+2 and d≥ k+1m−n−1 , and a(̸=0), b be two finite constants. Suppose that every f ∈F has all its zeros and poles of multiplicity at least k and d, respectively. If (fn)(k)−afm and (gn)(k)−agm share the value b for every pair of functions (f, g) of F, then F is normal in D. Our results improve the related theorems of Schwick (Schwick W. Normality criteria for families of meromorphic function. J. Anal. Math., 1989, 52:241–289), Li and Gu (Li Y T, Gu Y X. On normal families of meromorphic functions. J. Math. Anal. Appl., 2009, 354: 421–425).
A Generalized Cubic Functional Equation
Institute of Scientific and Technical Information of China (English)
P. K. SAHOO
2005-01-01
In this paper, we determine the general solution of the functional equation f1 (2x + y) +f2(2x - y) ＝ f3(x + y) + f4(x - y) + f5(x) without assuming any regularity condition on the unknown functions f1,f2,f3, f4,f5: R → R. The general solution of this equation is obtained by finding the general solution of the functional equations f(2x + y) + f(2x - y) = g(x + y) + g(x - y) + h(x) and f(2x + y) - f(2x - y) ＝ g(x + y) - g(x - y). The method used for solving these functional equations is elementary but exploits an important result due to Hosszu. The solution of this functional equation can also be determined in certain type of groups using two important results due to Székelyhidi.
Diagnostic approach to functional recovery
DEFF Research Database (Denmark)
Havsteen, Inger; Madsen, Kristoffer H; Christensen, Hanne Krarup;
2013-01-01
Stroke remains the most frequent cause of handicap in adult life and according to the WHO the second cause of death in the Western world. In the peracute phase, intravenous thrombolysis and in some cases endovascular therapy may induce early revascularization and hereby improve prognosis. However...... a substantial capacity to reorganize after a focal ischemic (or hemorrhagic) brain lesion. This functional reorganization contributes to functional recovery after stroke. Functional magnetic resonance imaging (fMRI) provides a valuable tool to capture the spatial and temporal activity changes in response...... available and does not pose any adverse effects, repeated fMRI measurements provide unprecedented possibilities to prospectively assess the time course of reorganization in functional neural networks after stroke and relate the temporospatial dynamics of reorganization at the systems level to functional...
Clinical evaluation of functional dysphonia.
Monday, L A
1983-10-01
Functional dysphonia is a voice impairment without any organic lesion of the phonating system. It may be classified into two categories: functional dysphonia itself where no lesions are found and functional laryngopathies where vocal cord lesions may be attributed to vocal abuse or misuse. The clinical evaluation of a dysphonic patient is performed in three steps: history taking, vocal evaluation, and examination. History taking helps the diagnosis and may be considered also as a therapeutic procedure. Vocal evaluation is oriented toward the voice itself and how it is produced. Then an ENT examination is performed with special attention to the larynx. In functional dysphonia, usually, everything looks normal but there may be signs of inflammation, hyperkinetism, hypokinetism, excessive laryngeal movements, etc. Functional laryngopathies include vocal nodules, laryngitis, polyps, and contact ulcer.
Global approximation of convex functions
Azagra, D
2011-01-01
We show that for every (not necessarily bounded) open convex subset $U$ of $\\R^n$, every (not necessarily Lipschitz or strongly) convex function $f:U\\to\\R$ can be approximated by real analytic convex functions, uniformly on all of $U$. In doing so we provide a technique which transfers results on uniform approximation on bounded sets to results on uniform approximation on unbounded sets, in such a way that not only convexity and $C^k$ smoothness, but also local Lipschitz constants, minimizers, order, and strict or strong convexity, are preserved. This transfer method is quite general and it can also be used to obtain new results on approximation of convex functions defined on Riemannian manifolds or Banach spaces. We also provide a characterization of the class of convex functions which can be uniformly approximated on $\\R^n$ by strongly convex functions.
Cryptographic Boolean functions and applications
Cusick, Thomas W
2009-01-01
Boolean functions are the building blocks of symmetric cryptographic systems. Symmetrical cryptographic algorithms are fundamental tools in the design of all types of digital security systems (i.e. communications, financial and e-commerce).Cryptographic Boolean Functions and Applications is a concise reference that shows how Boolean functions are used in cryptography. Currently, practitioners who need to apply Boolean functions in the design of cryptographic algorithms and protocols need to patch together needed information from a variety of resources (books, journal articles and other sources). This book compiles the key essential information in one easy to use, step-by-step reference. Beginning with the basics of the necessary theory the book goes on to examine more technical topics, some of which are at the frontier of current research.-Serves as a complete resource for the successful design or implementation of cryptographic algorithms or protocols using Boolean functions -Provides engineers and scient...
Correlation Functions and Power Spectra
DEFF Research Database (Denmark)
Larsen, Jan
2006-01-01
The present lecture note is a supplement to the textbook Digital Signal Processing by J. Proakis and D.G. Manolakis used in the IMM/DTU course 02451 Digital Signal Processing and provides an extended discussion of correlation functions and power spectra. The definitions of correlation functions...... and spectra for discrete-time and continuous-time (analog) signals are pretty similar. Consequently, we confine the discussion mainly to real discrete-time signals. The Appendix contains detailed definitions and properties of correlation functions and spectra for analog as well as discrete-time signals....... It is possible to define correlation functions and associated spectra for aperiodic, periodic and random signals although the interpretation is different. Moreover, we will discuss correlation functions when mixing these basic signal types. In addition, the note include several examples for the purpose...
Source time-function as discriminant using empirical Green's function
Institute of Scientific and Technical Information of China (English)
HE Yongfeng; CHEN Xiaofei
2005-01-01
The source mechanism of underground nuclear explosions is remarkably different from that of earthquakes in both spatial radiation pattern and source time-function (STF). Small underground nuclear explosions can be used as empirical Green's functions (EGF) to isolate the source-time spectrum of a large suspected earthquake occurred in a Nuclear Test Site (target area) by the spectral division method. As this study shows, with high-quality data, the quotient spectrum can be transformed to the time domain, yielding the apparent far-field source-time function of the large suspected event. The relative source time-function (RSTF) of a nuclear explosion is usually a simple pulse with a duration of about 1 s., while an earthquake's is more complicated with a series of pulses and a longer duration. The RSTF can be used as a nice discriminant to distinguish the nature earthquakes from underground nuclear explosions in target areas.
Triebel, Hans
1992-01-01
Theory of Function Spaces II deals with the theory of function spaces of type Bspq and Fspq as it stands at the present. These two scales of spaces cover many well-known function spaces such as Hölder-Zygmund spaces, (fractional) Sobolev spaces, Besov spaces, inhomogeneous Hardy spaces, spaces of BMO-type and local approximation spaces which are closely connected with Morrey-Campanato spaces. Theory of Function Spaces II is self-contained, although it may be considered an update of the author’s earlier book of the same title. The book’s 7 chapters start with a historical survey of the subject, and then analyze the theory of function spaces in Rn and in domains, applications to (exotic) pseudo-differential operators, and function spaces on Riemannian manifolds. ------ Reviews The first chapter deserves special attention. This chapter is both an outstanding historical survey of function spaces treated in the book and a remarkable survey of rather different techniques developed in the last 50 years. It is s...
Functional genomics of intracellular bacteria.
de Barsy, Marie; Greub, Gilbert
2013-07-01
During the genomic era, a large amount of whole-genome sequences accumulated, which identified many hypothetical proteins of unknown function. Rapidly, functional genomics, which is the research domain that assign a function to a given gene product, has thus been developed. Functional genomics of intracellular pathogenic bacteria exhibit specific peculiarities due to the fastidious growth of most of these intracellular micro-organisms, due to the close interaction with the host cell, due to the risk of contamination of experiments with host cell proteins and, for some strict intracellular bacteria such as Chlamydia, due to the absence of simple genetic system to manipulate the bacterial genome. To identify virulence factors of intracellular pathogenic bacteria, functional genomics often rely on bioinformatic analyses compared with model organisms such as Escherichia coli and Bacillus subtilis. The use of heterologous expression is another common approach. Given the intracellular lifestyle and the many effectors that are used by the intracellular bacteria to corrupt host cell functions, functional genomics is also often targeting the identification of new effectors such as those of the T4SS of Brucella and Legionella.
Spectral functions and transport coefficients from the functional renormalization group
Energy Technology Data Exchange (ETDEWEB)
Tripolt, Ralf-Arno
2015-06-03
In this thesis we present a new method to obtain real-time quantities like spectral functions and transport coefficients at finite temperature and density using the Functional Renormalization Group approach. Our non-perturbative method is thermodynamically consistent, symmetry preserving and based on an analytic continuation from imaginary to real time on the level of the flow equations. We demonstrate the applicability of this method by calculating mesonic spectral functions as well as the shear viscosity for the quark-meson model. In particular, results are presented for the pion and sigma spectral function at finite temperature and chemical potential, with a focus on the regime near the critical endpoint in the phase diagram of the quark-meson model. Moreover, the different time-like and space-like processes, which give rise to a complex structure of the spectral functions, are discussed. Finally, based on the momentum dependence of the spectral functions, we calculate the shear viscosity and the shear viscosity to entropy density ratio using the corresponding Green-Kubo formula.
2D Toda \\tau-functions as combinatorial generating functions
Guay-Paquet, Mathieu
2014-01-01
Two methods of constructing 2D Toda $\\tau$-functions that are generating functions for certain geometrical invariants of a combinatorial nature are related. The first involves generation of paths in the Cayley graph of the symmetric group $S_n$ by multiplication of the conjugacy class sums $C_\\lambda \\in C[S_n]$ in the group algebra by elements of an abelian group of central elements. Extending the characteristic map to the tensor product $C[S_n]\\otimes C[S_n]$ leads to double expansions in terms of power sum symmetric functions, in which the coefficients count the number of such paths. Applying the same map to sums over the orthogonal idempotents leads to diagonal double Schur function expansions that are identified as $\\tau$-functions of hypergeometric type. The second method is the standard construction of $\\tau$-functions as vacuum state matrix elements of products of vertex operators in a fermionic Fock space with elements of the abelian group of convolution symmetries. A homomorphism between these two g...
Intergenerational transmission of reflective functioning
Directory of Open Access Journals (Sweden)
Anna Maria Rosso
2016-12-01
Full Text Available The present study investigated whether, and to what extent, reflective functioning (RF during preadolescence is associated with maternal attachment security and reflective functioning, and with the child’s attachment security. Thirty-nine mother-preadolescent child dyads from a non clinical population participated in the study. Maternal and child RF were assessed by applying the Reflective Functioning Scale (RFS to the Adult Attachment Interview (AAI and to the Child Attachment Interview (CAI transcripts. Children of mothers who showed a secure attachment model regarding the relationship with their parents during childhood reported higher levels of RF than the children of mothers who were classified as insecure on the AAI. Child RF was positively associated with maternal Coherence of the Mind on the AAI and negatively associated with maternal derogation of attachment.A strong, significant association was also found between child attachment security and child reflective functioning. Children who were rated as being more emotionally open, more able to balance positive and negative descriptions of their parents, more prone to support their assertions through examples, and more able to positively resolve conflicts with their parents showed higher reflective functioning. On the contrary, children who resorted to a higher extent to idealization and dismissal towards their parents showed a lesser degree of reflective functioning. Notably, a very strong association was found between the score on the Overall coherence subscale and the child’s ability to mentalise mixed-ambivalent mental states in the context of their family relationships.As expected, child and maternal reflective functioning resulted significantly positively correlated with each other. In particular, only maternal reflective functioning (and not maternal attachment security predicted child reflective functioning, and only maternal ability to mentalise mixed-ambivalent mental states
Functional Food Science in Europe.
Contor, L
2001-08-01
The goal of the Functional Food Science in Europe (FUFOSE) concerted action was to reach consensus on scientific concepts of functional foods in Europe by using the science base that supports evidence that specific nutrients positively affect physiological functions. The outcome proposes "a working definition" of functional foods: foods can be regarded as functional if they can be satisfactorily demonstrated to affect beneficially one or more target functions in the body, beyond adequate nutritional effects, in a way relevant to an improved state of health and well-being and/or reduction of risk of disease. Functional foods must remain foods and they must achieve their effects in amounts normally consumed in a diet. Evidence from human studies, based on markers relating to biological response or on intermediate endpoint markers of disease, could provide a sound scientific basis for messages and claims about the functional food products. Two types of claims are proposed that relate directly to these two categories of markers: Enhanced function claims (type A) and reduced risk of disease claims (type B). A new EU Concerted Action will start with, and build upon, the principles defined within FUFOSE. This project PASSCLAIM will (i) produce a consensus on principles for the scientific substantiation of health-related claims for food and food components, (ii) select common criteria for how markers should be identified, validated and used in well-designed studies to explore the links between diet and health and (iii) to evaluate critically the existing schemes which assess the scientific substantiation of claims.
Quasisymmetric functions and Heisenberg doubles
Directory of Open Access Journals (Sweden)
Jie Sun
2016-09-01
Full Text Available The ring of quasisymmetric functions is free over the ring of symmetric functions. This result waspreviously proved by M. Hazewinkel combinatorially through constructing a polynomial basis forquasisymmetric functions. The recent work by A. Savage and O. Yacobi on representation theoryprovides a new proof to this result. In this paper, we proved that under certain conditions, thepositive part of a Heisenberg double is free over the positive part of the corresponding projectiveHeisenberg double. Examples satisfying the above conditions are discussed.
The mythic function of narcissism.
Aversa, G Luigi; Baldieri, Vittoria; Marozza, Maria Ilena
2004-09-01
The paper makes some critical comments on the use Freud makes of myth and examines some of the inconsistencies and contradictions in his conceptualization of narcissism. Using some of the ideas of Bachelard and Hillman on the role of the imaginary, the authors theorize a function of myth that is independent of and not subordinated to the reality function. They suggest that narcissism must be seen not only in terms of individual history but that it has a mythic function; narcissism facilitates the creation of a relationship between the ego and the Self through the mediation of the imaginal world and through the prospective value of images.
Normal families of meromorphic functions
Institute of Scientific and Technical Information of China (English)
MA Chao-wei; WANG Yong-jun
2007-01-01
A normal theorem concerning meromorphic functions sharing values was proved with the method of Zalcman-Pang.The theorem is as follows.If for each f in F,all zeros of f-a have multiplicity at least k(k≥2),f and its k-th derivative function share a,and if f=b whenever its k-th denvative equal b,then F is normal in D.This theorem improved the result of Chen and Fang[Chen HH,Fang ML,Shared values and normal families of meromorphic functions,Journal of Mathematical Analysis and Applications,2001,260:124-1 32].
Various Shades of Blue's Functions
Janik, R A; Papp, G; Zahed, I; Janik, Romuald A.; Nowak, Maciej A.; Papp, Gabor; Zahed, Ismail
1997-01-01
We discuss random matrix models in terms of elementary operations on Blue's functions (functional inverse of Green's functions). We show that such operations embody the essence of a number of physical phenomena whether at/or away from the critical points. We illustrate these assertions by borrowing on a number of recent results in effective QCD in vacuum and matter. We provide simple physical arguments in favor of the universality of the continuum QCD spectral oscillations, whether at zero virtuality, in the bulk of the spectrum or at the chiral critical points. We also discuss effective quantum systems of disorder with strong or weak dissipation (Hatano-Nelson localization).
Geometric Operators on Boolean Functions
DEFF Research Database (Denmark)
Frisvad, Jeppe Revall; Falster, Peter
function. With this image of a Boolean function corresponding to a propositional formula, we prove that the orthogonal projection operator leads to a theorem describing all rules of inference in propositional reasoning. In other words, we can capture all kinds of inference in propositional logic by means...... independent of representation such that we no longer need to be much concerned with the form of the Boolean functions. Knowing that the operators can easily be implemented (as they have been in array-based logic), shows the advantage they give with respect to automated reasoning....
Function spaces on local fields
Institute of Scientific and Technical Information of China (English)
SU; Weiyi; XU; Qiang
2006-01-01
We study the function spaces on local fields in this paper, such as Triebel Btype and F-type spaces, Holder type spaces, Sobolev type spaces, and so on, moreover,study the relationship between the p-type derivatives and the Holder type spaces. Our obtained results show that there exists quite difference between the functions defined on Euclidean spaces and local fields, respectively. Furthermore, many properties of functions defined on local fields motivate the new idea of solving some important topics on fractal analysis.
Accurate computation of Mathieu functions
Bibby, Malcolm M
2013-01-01
This lecture presents a modern approach for the computation of Mathieu functions. These functions find application in boundary value analysis such as electromagnetic scattering from elliptic cylinders and flat strips, as well as the analogous acoustic and optical problems, and many other applications in science and engineering. The authors review the traditional approach used for these functions, show its limitations, and provide an alternative ""tuned"" approach enabling improved accuracy and convergence. The performance of this approach is investigated for a wide range of parameters and mach
Recursive Definitions of Monadic Functions
Krauss, Alexander
2010-01-01
Using standard domain-theoretic fixed-points, we present an approach for defining recursive functions that are formulated in monadic style. The method works both in the simple option monad and the state-exception monad of Isabelle/HOL's imperative programming extension, which results in a convenient definition principle for imperative programs, which were previously hard to define. For such monadic functions, the recursion equation can always be derived without preconditions, even if the function is partial. The construction is easy to automate, and convenient induction principles can be derived automatically.
Incentives in Supply Function Equilibrium
DEFF Research Database (Denmark)
Vetter, Henrik
2014-01-01
The author analyses delegation in homogenous duopoly under the assumption that the firm-managers compete in supply functions. In supply function equilibrium, managers’ decisions are strategic complements. This reverses earlier findings in that the author finds that owners give managers incentives...... to act in an accommodating way. As a result, optimal delegation reduces per-firm output and increases profits to above-Cournot profits. Moreover, in supply function equilibrium the mode of competition is endogenous. This means that the author avoids results that are sensitive with respect to assuming...
Functional observer and state feedback
Energy Technology Data Exchange (ETDEWEB)
Zhang, S.Y.
1986-01-01
In this paper, we show the relation between state space approach and transfer function approach for functional observer and state feedback design. Two approaches can be transformed into each other, based on this result. More importantly, we find that the state space approach introduces some severe, unnecessary restrictions in solving the problem. The restrictions are, however, reduced to be a trivial condition in transfer function approach. It is believed that the result presented in this paper will be useful in developing both approaches, and motivate some new results for solving the problem.
Recursive Definitions of Monadic Functions
Directory of Open Access Journals (Sweden)
Alexander Krauss
2010-12-01
Full Text Available Using standard domain-theoretic fixed-points, we present an approach for defining recursive functions that are formulated in monadic style. The method works both in the simple option monad and the state-exception monad of Isabelle/HOL's imperative programming extension, which results in a convenient definition principle for imperative programs, which were previously hard to define. For such monadic functions, the recursion equation can always be derived without preconditions, even if the function is partial. The construction is easy to automate, and convenient induction principles can be derived automatically.
Theta functions and mirror symmetry
Gross, Mark
2012-01-01
This is a survey covering aspects of varied work of the authors with Mohammed Abouzaid, Paul Hacking, and Sean Keel. While theta functions are traditionally canonical sections of ample line bundles on abelian varieties, we motivate, using mirror symmetry, the idea that theta functions exist in much greater generality. This suggestion originates with the work of the late Andrei Tyurin. We outline how to construct theta functions on the degenerations of varieties constructed in previous work of the authors, and then explain applications of this construction to homological mirror symmetry and constructions of broad classes of mirror varieties.
Hilbertian kernels and spline functions
Atteia, M
1992-01-01
In this monograph, which is an extensive study of Hilbertian approximation, the emphasis is placed on spline functions theory. The origin of the book was an effort to show that spline theory parallels Hilbertian Kernel theory, not only for splines derived from minimization of a quadratic functional but more generally for splines considered as piecewise functions type. Being as far as possible self-contained, the book may be used as a reference, with information about developments in linear approximation, convex optimization, mechanics and partial differential equations.
Function Concepts for Machine Parts
DEFF Research Database (Denmark)
Mortensen, Niels Henrik
1999-01-01
The majority of resources, like time and costs, consumed in industrial product development can be related to detailed design, i.e. the materialisation of machine parts (German Maschinenteile). Existing design theories based on a systems approach, e.g. Haberfellner [5] all have function, i.......e. transformation from input to output or ability to deliver purposeful effects as the core concept. The units in a product which posses functions are the organs (German: Funktionsträgern). Because individual parts do not posses functions, one could argue that the design theories based on a systems approach...... to be identification of a purposeful behaviour concept, i.e. function for a machine part. The contribution is based on the theory of technical systems, Hubka and the domain theory, Andreasen....
Functions and Mechanisms of Sleep
Directory of Open Access Journals (Sweden)
Mark R. Zielinski
2016-04-01
Full Text Available Sleep is a complex physiological process that is regulated globally, regionally, and locally by both cellular and molecular mechanisms. It occurs to some extent in all animals, although sleep expression in lower animals may be co-extensive with rest. Sleep regulation plays an intrinsic part in many behavioral and physiological functions. Currently, all researchers agree there is no single physiological role sleep serves. Nevertheless, it is quite evident that sleep is essential for many vital functions including development, energy conservation, brain waste clearance, modulation of immune responses, cognition, performance, vigilance, disease, and psychological state. This review details the physiological processes involved in sleep regulation and the possible functions that sleep may serve. This description of the brain circuitry, cell types, and molecules involved in sleep regulation is intended to further the reader’s understanding of the functions of sleep.
Functionalized carbon nanotubes: biomedical applications.
Vardharajula, Sandhya; Ali, Sk Z; Tiwari, Pooja M; Eroğlu, Erdal; Vig, Komal; Dennis, Vida A; Singh, Shree R
2012-01-01
Carbon nanotubes (CNTs) are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs limits their use in humans and many biological systems. The biocompatibility and low cytotoxicity of CNTs are attributed to size, dose, duration, testing systems, and surface functionalization. The functionalization of CNTs improves their solubility and biocompatibility and alters their cellular interaction pathways, resulting in much-reduced cytotoxic effects. Functionalized CNTs are promising novel materials for a variety of biomedical applications. These potential applications are particularly enhanced by their ability to penetrate biological membranes with relatively low cytotoxicity. This review is directed towards the overview of CNTs and their functionalization for biomedical applications with minimal cytotoxicity.
Hot topics in functional neuroradiology.
Faro, S H; Mohamed, F B; Helpern, J A; Jensen, J H; Thulborn, K R; Atkinson, I C; Sair, H I; Mikulis, D J
2013-12-01
Functional neuroradiology represents a relatively new and ever-growing subspecialty in the field of neuroradiology. Neuroradiology has evolved beyond anatomy and basic tissue signal characteristics and strives to understand the underlying physiologic processes of central nervous system disease. The American Society of Functional Neuroradiology sponsors a yearly educational and scientific meeting, and the educational committee was asked to suggest a few cutting-edge functional neuroradiology techniques (hot topics). The following is a review of several of these topics and includes "Diffusion Tensor Imaging of the Pediatric Spinal Cord"; "Diffusional Kurtosis Imaging"; "From Standardization to Quantification: Beyond Biomarkers toward Bioscales as Neuro MR Imaging Surrogates of Clinical End Points"; Resting-State Functional MR Imaging"; and "Current Use of Cerebrovascular Reserve Imaging."
Flat affect and social functioning
DEFF Research Database (Denmark)
Simonsen, Erik; Evensen, Julie; Røsberg, Jan Ivar;
2012-01-01
, predictors and outcome factors including social functioning. Methods: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped...... as having never-present, improving, deteriorating, fluctuating or enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period. Results: Twenty nine percent never displayed FA, 66% had improving, deteriorating...... or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring, fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning...
Selective Functionalization of Tailored Nanostructures
Slingenbergh, Winand; Boer, Sanne K. de; Cordes, Thorben; Browne, Wesley R.; Feringa, Ben L.; Hoogenboom, Jacob P.; Hosson, Jeff Th.M. De; Dorp, Willem F. van
2012-01-01
The controlled positioning of nanostructures with active molecular components is of importance throughout nanoscience and nanotechnology. We present a novel three-step method to produce nanostructures that are selectively decorated with functional molecules. We use fluorophores and nanoparticles to
Cell elasticity determines macrophage function.
Directory of Open Access Journals (Sweden)
Naimish R Patel
Full Text Available Macrophages serve to maintain organ homeostasis in response to challenges from injury, inflammation, malignancy, particulate exposure, or infection. Until now, receptor ligation has been understood as being the central mechanism that regulates macrophage function. Using macrophages of different origins and species, we report that macrophage elasticity is a major determinant of innate macrophage function. Macrophage elasticity is modulated not only by classical biologic activators such as LPS and IFN-γ, but to an equal extent by substrate rigidity and substrate stretch. Macrophage elasticity is dependent upon actin polymerization and small rhoGTPase activation, but functional effects of elasticity are not predicted by examination of gene expression profiles alone. Taken together, these data demonstrate an unanticipated role for cell elasticity as a common pathway by which mechanical and biologic factors determine macrophage function.
Functional genomics by mass spectrometry
DEFF Research Database (Denmark)
Andersen, Jens S.; Mann, M
2000-01-01
Systematic analysis of the function of genes can take place at the oligonucleotide or protein level. The latter has the advantage of being closest to function, since it is proteins that perform most of the reactions necessary for the cell. For most protein based ('proteomic') approaches to gene...... function, mass spectrometry is the method of choice. Mass spectrometry can now identify proteins with very high sensitivity and medium to high throughput. New instrumentation for the analysis of the proteome has been developed including a MALDI hybrid quadrupole time of flight instrument which combines...... numbers of intact proteins by mass spectrometry directly. Examples from this laboratory illustrate biological problem solving by modern mass spectrometric techniques. These include the analysis of the structure and function of the nucleolus and the analysis of signaling complexes....
Density functionals from deep learning
McMahon, Jeffrey M
2016-01-01
Density-functional theory is a formally exact description of a many-body quantum system in terms of its density; in practice, however, approximations to the universal density functional are required. In this work, a model based on deep learning is developed to approximate this functional. Deep learning allows computational models that are capable of naturally discovering intricate structure in large and/or high-dimensional data sets, with multiple levels of abstraction. As no assumptions are made as to the form of this structure, this approach is much more powerful and flexible than traditional approaches. As an example application, the model is shown to perform well on approximating the kinetic-energy density functional for noninteracting electrons. The model is analyzed in detail, and its advantages over conventional machine learning are discussed.
On some positive definite functions
Bhatia, Rajendra; Jain, Tanvi
2014-01-01
We study the function $(1 - \\|x\\|)\\slash (1 - \\|x\\|^r),$ and its reciprocal, on the Euclidean space $\\mathbb{R}^n,$ with respect to properties like being positive definite, conditionally positive definite, and infinitely divisible.
Functional aspects of protein flexibility
DEFF Research Database (Denmark)
Teilum, Kaare; Olsen, Johan G; Kragelund, Birthe B
2009-01-01
Proteins are dynamic entities, and they possess an inherent flexibility that allows them to function through molecular interactions within the cell, among cells and even between organisms. Appreciation of the non-static nature of proteins is emerging, but to describe and incorporate...... this into an intuitive perception of protein function is challenging. Flexibility is of overwhelming importance for protein function, and the changes in protein structure during interactions with binding partners can be dramatic. The present review addresses protein flexibility, focusing on protein-ligand interactions....... The thermodynamics involved are reviewed, and examples of structure-function studies involving experimentally determined flexibility descriptions are presented. While much remains to be understood about protein flexibility, it is clear that it is encoded within their amino acid sequence and should be viewed...
Lacking power impairs executive functions
Smith, P.K.; Jostmann, N.B.; Galinsky, A.D.; Dijk, W.W. van
2008-01-01
Four experiments explored whether lacking power impairs executive functioning, testing the hypothesis that the cognitive presses of powerlessness increase vulnerability to performance decrements during complex executive tasks. In the first three experiments, low power impaired performance on executi
Simple fixed functional space maintainer.
Goenka, Puneet; Sarawgi, Aditi; Marwah, Nikhil; Gumber, Parvind; Dutta, Samir
2014-01-01
Premature loss of a primary tooth is one of the most common etiology for malocclusion. Space maintainers are employed to prevent this complication. In anterior region, esthetics is an important concern along with function and space management. Fiber-reinforced composite (FRC) retained space maintainer solves all these purposes ef ficiently and ef fectively. In addition, the technique is simple and the appliance is very comfortable inside the oral cavity. Here is a case of premature loss of anterior primary tooth which was replaced by FRC retained esthetic functional space maintainer. The appliance was found to be functioning satisfactorily inside the oral cavity till the last visit (1 Year). How to cite this article: Goenka P, Sarawgi A, Marwah N, Gumber P, Dutta S. Simple Fixed Functional Space Maintainer. Int J Clin Pediatr Dent 2014;7(3):225-228.
Towards a reversible functional language
DEFF Research Database (Denmark)
Yokoyama, Tetsuo; Axelsen, Holger Bock; Glück, Robert
2012-01-01
first-match policy for case expressions, we can write overlapping patterns in case branches, as is customary in ordinary functional languages, and also in leaf expressions, unlike existing inverse interpreter methods, which enables concise programs. In patterns, the use of a duplication......We identify concepts of reversibility for a functional language by means of a set of semantic rules with specific properties. These properties include injectivity along with local backward determinism, an important operational property for an efficient reversible language. We define a concise...... reversible first-order functional language in which access to the backward semantics is provided to the programmer by inverse function calls. Reversibility guarantees that in this language a backward run (inverse interpretation) is as fast as the corresponding forward run itself. By adopting a symmetric...
COMPARING EXTRACTIONS OF SIVERS FUNCTIONS.
Energy Technology Data Exchange (ETDEWEB)
VOGELSANG, W.
2005-09-07
A comparison is given of the various recently published extractions of the Sivers functions from the HERMES and COMPASS data on single-transverse spin asymmetries in semi-inclusive deeply inelastic scattering.
Functionalized silica materials for electrocatalysis
Indian Academy of Sciences (India)
Vellaichamy Ganesan
2015-02-01
Electrocatalysis is an important phenomenon which is utilized in metal–air batteries, fuel cells, electrochemical sensors, etc. To increase the efficiency of the electrocatalytic process and to increase the electrochemical accessibility of the immobilized electrocatalysts, functionalized and non-functionalized mesoporous organo-silica (MCM41-type-materials) are used in this study. These materials possess several suitable properties to be durable catalysts and/or catalyst supports. Owing to the uniform dispersion of electrocatalysts (metal complex and/or metal nanoparticles (NPs)) on the functionalized and non-functionalized silica, an enormous increase in the redox current is observed. Long range channels of silica materials with pore diameter of 15–100 Å allowed metal NPs to accommodate in a specified manner in addition to other catalysts. The usefulness of MCM-41-type silica in increasing the efficiency of electrocatalysisis demonstrated by selecting oxygen, carbon dioxide and nitrite reduction reactions as examples
Caustic ingestion and esophageal function
Energy Technology Data Exchange (ETDEWEB)
Cadranel, S.; Di Lorenzo, C.; Rodesch, P.; Piepsz, A.; Ham, H.R. (Children University Hospital, Brussels (Belgium))
1990-02-01
The aim of the present study was to investigate esophageal motor function by means of krypton-81m esophageal transit scintigraphy and to compare the results with the functional and morphological data obtained by means of triple lumen manometry and endoscopy. In acute and subacute stages of the disease, all clinical, anatomical, and functional parameters were in good agreement, revealing significant impairment. In chronic stages, the severity of the dysphagia was not correlated to the importance of the residual stenosis. Conversely, 81mKr esophageal transit and manometric's findings were in good agreement with the clinical symptoms, during the entire follow-up period ranging between 3 months to 7 years. The 81mKr test is undoubtedly the easiest and probably the most physiological technique currently available for long-term functional evaluation of caustic esophagitis.
On Local Integrated Cosine Functions
Institute of Scientific and Technical Information of China (English)
SHI Jin-e; ZHENG Wei-xing
2001-01-01
Suppose X is a Banach space, and A is a closed operator. We give some equivalent conditions between A generating a local integrated cosine functions and the existence of solutions of abstract Cauchy problems.
Covering Numbers for Convex Functions
Guntuboyina, Adityanand
2012-01-01
In this paper we study the covering numbers of the space of convex and uniformly bounded functions in multi-dimension. We find optimal upper and lower bounds for the $\\epsilon$-covering number of $\\C([a, b]^d, B)$, in the $L_p$-metric, $1 \\le p 0$, and $\\C([a,b]^d, B)$ denotes the set of all convex functions on $[a, b]^d$ that are uniformly bounded by $B$. We summarize previously known results on covering numbers for convex functions and also provide alternate proofs of some known results. Our results have direct implications in the study of rates of convergence of empirical minimization procedures as well as optimal convergence rates in the numerous convexity constrained function estimation problems.
Functional methods in differential equations
Hokkanen, Veli-Matti
2002-01-01
In recent years, functional methods have become central to the study of theoretical and applied mathematical problems. As demonstrated in this Research Note, functional methods can not only provide more generality, but they can also unify results and techniques and lead to better results than those obtained by classical methods. Presenting entirely original results, the authors use functional methods to explore a broad range of elliptic, parabolic, and hyperbolic boundary value problems and various classes of abstract differential and integral equations. They show that while it is crucial to choose an appropriate functional framework, this approach can lead to mathematical models that better describe concrete physical phenomena. In particular, they reach a concordance between the physical sense and the mathematical sense for the solutions of some special models. Beyond its importance as a survey of the primary techniques used in the area, the results illuminated in this volume will prove valuable in a wealth ...
Willingness to use functional breads
DEFF Research Database (Denmark)
Vassallo, Marco; Saba, Anna; Arvola, Anna
2009-01-01
which was significant only in Finland. Young consumers seemed more interested in the functional bread with a health claim promoting health rather than in reducing risk of disease, whereas the opposite was true for older people. However, functional staple foods, such as bread in this European study...... characteristics due to the addition of the functional ingredients. The importance of health motivation in willingness to use products with health claims implies that there is an opening for developing better models for explaining health-promoting food choices that take into account both food and health......The present study focused on the role of the Health Belief Model (HBM) in predicting willingness to use functional breads, across four European countries: UK (N = 552), Italy (N = 504), Germany (N = 525) and Finland (N = 513). The behavioural evaluation components of the HBM (the perceived benefits...
Emotional Profile and Intellectual Functioning
Directory of Open Access Journals (Sweden)
Marianna Alesi
2015-07-01
Full Text Available Insufficient literature has been produced addressing children with borderline intellectual functioning (BIF and gifted intellectual functioning (GIF. The goal of this work is to compare levels of self-esteem, depression, anxiety at school, and insecurity among children with BIF and GIF, and a control group of average intellectual functioning (AIF. There were participants of 104 children (fourth grade of primary school. Analyses revealed that children with BIF showed a lower level of self-esteem and higher levels of depression and school anxiety. Moreover, our findings highlight the co-occurrence of school anxiety, depressed mood, and insecurity among the BIF and AIF groups. One of the issues that emerge from this study is the need to implement prevention programs aimed at identifying children with lower or higher levels of intellectual functioning. These findings highlight the importance of establishing what the most appropriate educational and clinical interventions are in reducing the risks of mental disorders in this population.
Sexual function after transvaginal cholecystectomy
DEFF Research Database (Denmark)
Donatsky, Anders M; Jørgensen, Lars N; Meisner, Søren;
2014-01-01
INTRODUCTION: Despite several benefits, patients are concerned that transvaginal cholecystectomy has a negative impact on sexual health. The objective of this systematic review was to assess the impact of transvaginal cholecystectomy on postoperative dyspareunia and sexual function. METHOD......: A literature search was performed in the PubMed and EMBASE databases. Papers reporting on postoperative dyspareunia, vaginal pain or discomfort, and sexual function were included. RESULTS: Seventeen papers reported on dyspareunia and vaginal pain or discomfort. Two papers reported a rate of de novo dyspareunia...... of 3.8% and 12.5%, respectively. One study reported a nonsignificant reduction in painful sexual intercourse and the remaining 14 reported no incidents of dyspareunia. Eight papers reported on sexual function. One paper using a nonvalidated questionnaire found impaired sexual function. The papers...
Making the Tent Function Complex
Sprows, David J.
2010-01-01
This note can be used to illustrate to the student such concepts as periodicity in the complex plane. The basic construction makes use of the Tent function which requires only that the student have some working knowledge of binary arithmetic.
Special Functions for Applied Scientists
Mathai, A M
2008-01-01
Special Functions for Applied Scientists provides the required mathematical tools for researchers active in the physical sciences. The book presents a full suit of elementary functions for scholars at the PhD level and covers a wide-array of topics and begins by introducing elementary classical special functions. From there, differential equations and some applications into statistical distribution theory are examined. The fractional calculus chapter covers fractional integrals and fractional derivatives as well as their applications to reaction-diffusion problems in physics, input-output analysis, Mittag-Leffler stochastic processes and related topics. The authors then cover q-hypergeometric functions, Ramanujan's work and Lie groups. The latter half of this volume presents applications into stochastic processes, random variables, Mittag-Leffler processes, density estimation, order statistics, and problems in astrophysics. Professor Dr. A.M. Mathai is Emeritus Professor of Mathematics and Statistics, McGill ...
Interference in discrete Wigner functions
Cormick, C; Cormick, Cecilia; Paz, Juan Pablo
2006-01-01
We analyse some features of the class of discrete Wigner functions that was recently introduced by Gibbons et al. to represent quantum states of systems with power-of-prime dimensional Hilbert spaces [Phys. Rev. A 70, 062101 (2004)]. We consider "cat" states obtained as coherent superpositions of states with positive Wigner function; for such states we show that the oscillations of the discrete Wigner function typically spread over the entire discrete phase-space (including the regions where the two interfering states are localized). This is a generic property which is in sharp contrast with the usual attributes of Wigner functions that make them useful candidates to display the existence of quantum coherence through oscillations. However, it is possible to find subsets of cat states with a natural phase-space representation, in which the oscillatory regions remain localized. We show that this can be done for interesting families of stabilizer states used in quantum error-correcting codes, and illustrate this...
Monogenic Functions in Conformal Geometry
Directory of Open Access Journals (Sweden)
Michael Eastwood
2007-08-01
Full Text Available Monogenic functions are basic to Clifford analysis. On Euclidean space they are defined as smooth functions with values in the corresponding Clifford algebra satisfying a certain system of first order differential equations, usually referred to as the Dirac equation. There are two equally natural extensions of these equations to a Riemannian spin manifold only one of which is conformally invariant. We present a straightforward exposition.
Selective functionalization of carbon nanotubes
Strano, Michael S. (Inventor); Usrey, Monica (Inventor); Barone, Paul (Inventor); Dyke, Christopher A. (Inventor); Tour, James M. (Inventor); Kittrell, W. Carter (Inventor); Hauge, Robert H. (Inventor); Smalley, Richard E. (Inventor)
2009-01-01
The present invention is directed toward methods of selectively functionalizing carbon nanotubes of a specific type or range of types, based on their electronic properties, using diazonium chemistry. The present invention is also directed toward methods of separating carbon nanotubes into populations of specific types or range(s) of types via selective functionalization and electrophoresis, and also to the novel compositions generated by such separations.
Normal Functions Concerning Shared Values
Institute of Scientific and Technical Information of China (English)
WANG XIAO-JING
2009-01-01
In this paper we discuss normal functions concerning shared values. We obtain the follow result. Let F be a family of meromorphic functions in the unit disc △, and a be a nonzero finite complex number. If for any f ∈ F, the zeros of f are of multiplicity, f and f' share a, then there exists a positive number M such that for any f ∈ F, (1 -|z|~2)(|f'(z)|)/(1+|f(z)|~2)≤ M.
Rho GTPase function in development
DEFF Research Database (Denmark)
Pedersen, Esben; Brakebusch, Cord
2012-01-01
Rho GTPase functions have been carefully investigated for many years using cell biological models. In recent years, mouse models with targeted mutations in Rho GTPase genes enabled the study of Rho GTPase function in vivo, partially confirming and partially contradicting expectations based...... on earlier in vitro experiments. This review sums up recent findings on the role of Rho GTPases in development, underlining the importance of in vivo research for our understanding of Rho GTPases in living organisms, and describing challenges for the future....
Beta Function and Anomalous Dimensions
Pica, Claudio
2010-01-01
We demonstrate that it is possible to determine the coefficients of an all-order beta function linear in the anomalous dimensions using as data the two-loop coefficients together with the first one of the anomalous dimensions which are universal. The beta function allows to determine the anomalous dimension of the fermion masses at the infrared fixed point, and the resulting values compare well with the lattice determinations.
Functionalized magnetic nanoparticle analyte sensor
Yantasee, Wassana; Warner, Maryin G; Warner, Cynthia L; Addleman, Raymond S; Fryxell, Glen E; Timchalk, Charles; Toloczko, Mychailo B
2014-03-25
A method and system for simply and efficiently determining quantities of a preselected material in a particular solution by the placement of at least one superparamagnetic nanoparticle having a specified functionalized organic material connected thereto into a particular sample solution, wherein preselected analytes attach to the functionalized organic groups, these superparamagnetic nanoparticles are then collected at a collection site and analyzed for the presence of a particular analyte.
Operational calculus and generalized functions
Erdelyi, Arthur
2013-01-01
This brief monograph by a distinguished professor is based on a mathematics course offered at the California Institute of Technology. The majority of students taking this course were advanced undergraduates and graduate students of engineering. A solid background in advanced calculus is a prerequisite.Topics include elementary and convergence theories of convolution quotients, differential equations involving operator functions, and exponential functions of operators. Tools developed in the preceding chapters are then applied to problems in partial differential equations. Solutions to selected
DEFF Research Database (Denmark)
Dawes, C; Pedersen, Anne Marie Lynge; Villa, A
2015-01-01
a moist oral mucosa which is less susceptible to abrasion, and removal of micro-organisms, desquamated epithelial cells, leucocytes and food debris by swallowing. The mucins form a slimy coating on all surfaces in the mouth and act as a lubricant during such processes as mastication, formation of a food...... of oral wounds. Clearly, saliva has many functions which are needed for proper protection and functioning of the human body....
Drug treatment of functional dyspepsia
Institute of Scientific and Technical Information of China (English)
Klaus M(o)nkemüller; Peter Malfertheiner
2006-01-01
Symptomatic improvement of patients with functional dyspepsia after drug therapy is often incomplete and obtained in not more than 60% of patients. This is likely because functional dyspepsia is a heterogeneous disease.Although great advance has been achieved with the consensus definitions of the Rome Ⅰ and Ⅱ criteria, there are still some aspects about the definition of functional dyspepsia that require clarification. The Rome criteria explicitly recognise that epigastric pain or discomfort must be the predominant complaint in patients labelled as suffering from functional dyspepsia. However, this strict definition can create problems in the daily primary care clinical practice, where the patient with functional dyspepsia presents with multiple symptoms. Before starting drug therapy it is recommended to provide the patient with an explanation of the disease process and reassurance. A thorough physical examination and judicious use of laboratory data and endoscopy are also indicated. In general, the approach to treat patients with functional dyspepsia based on their main symptom is practical and effective. Generally, patients should be treated with acid suppressive therapy using proton-pump inhibitors if the predominant symptoms are epigastric pain or gastroesophageal reflux symptoms. Although the role of Helicobacter pylori(H pylori) in functional dyspepsia continues to be a matter of debate, recent data indicate that there is modest but clear benefit of eradication of H pylori in patients with functional dyspepsia. In addition,H pylori is a gastric carcinogen arid if found it should be eliminated. Although there are no specific diets for patients with FD, it may be helpful to guide the patients on healthy exercise and eating habits.
Inductance and hypergeometric functions. II
DEFF Research Database (Denmark)
Karlsson, Per W.
2000-01-01
A previously obtained integral for the self-inductance of a solenoid is further transformed. The resulting formula involves double Kampé de Fériet functions which are analytic continuations rather than power series.......A previously obtained integral for the self-inductance of a solenoid is further transformed. The resulting formula involves double Kampé de Fériet functions which are analytic continuations rather than power series....
Automatic computation of transfer functions
Atcitty, Stanley; Watson, Luke Dale
2015-04-14
Technologies pertaining to the automatic computation of transfer functions for a physical system are described herein. The physical system is one of an electrical system, a mechanical system, an electromechanical system, an electrochemical system, or an electromagnetic system. A netlist in the form of a matrix comprises data that is indicative of elements in the physical system, values for the elements in the physical system, and structure of the physical system. Transfer functions for the physical system are computed based upon the netlist.
Formalism and functionalism in linguistics.
Newmeyer, Frederick J
2010-05-01
Formalism and functionalism in linguistics are often taken to be diametrically opposed approaches. However, close examination of the relevant phenomena reveals that the two are complementary, rather than being irrevocably in opposition to each other. One can be a formal linguist and a functional linguist at the same time, without there being any contradiction. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.
Functional Coatings with Polymer Brushes
König, Meike
2013-01-01
The scope of this work is to fathom different possibilities to create functional coatings with polymer brushes. The immobilization of nanoparticles and enzymes is investigated, as well as the affection of their properties by the stimuli-responsiveness of the brushes. Another aspect is the coating of 3D-nanostructures by polymer brushes and the investigation of the resulting functional properties of the hybrid material. The polymer brush coatings are characterized by a variety of microscopic a...
Functional neuroimaging and childhood autism
Energy Technology Data Exchange (ETDEWEB)
Boddaert, Nathalie [Service de Radiologie Pediatrique, Necker-Enfants Malades Hospital, Paris (France); Service Hospitalier Frederic Joliot, DRM, DSV, CEA, Orsay (France); Zilbovicius, Monica [Service Hospitalier Frederic Joliot, DRM, DSV, CEA, Orsay (France); INSERM, Tours (France)
2002-01-01
Childhood autism is now widely viewed as being of developmental neurobiological origin. Yet, localised structural and functional brain correlates of autism have to be established. Structural brain-imaging studies performed in autistic patients have reported abnormalities such as increased total brain volume and cerebellar abnormalities. However, none of these abnormalities fully account for the full range of autistic symptoms. Functional brain imaging, such as positron emission tomography (PET), single photon emission computed tomography (SPECT) and functional MRI (fMRI) have added a new perspective to the study of normal and pathological brain functions. In autism, functional studies have been performed at rest or during activation. However, first-generation functional imaging devices were not sensitive enough to detect any consistent dysfunction. Recently, with improved technology, two independent groups have reported bilateral hypoperfusion of the temporal lobes in autistic children. In addition, activation studies, using perceptive and cognitive paradigms, have shown an abnormal pattern of cortical activation in autistic patients. These results suggest that different connections between particular cortical regions could exist in autism. The purpose of this review is to present the main results of rest and activation studies performed in autism. (orig.)
Boolean networks with veto functions
Ebadi, Haleh; Klemm, Konstantin
2014-08-01
Boolean networks are discrete dynamical systems for modeling regulation and signaling in living cells. We investigate a particular class of Boolean functions with inhibiting inputs exerting a veto (forced zero) on the output. We give analytical expressions for the sensitivity of these functions and provide evidence for their role in natural systems. In an intracellular signal transduction network [Helikar et al., Proc. Natl. Acad. Sci. USA 105, 1913 (2008), 10.1073/pnas.0705088105], the functions with veto are over-represented by a factor exceeding the over-representation of threshold functions and canalyzing functions in the same system. In Boolean networks for control of the yeast cell cycle [Li et al., Proc. Natl. Acad. Sci. USA 101, 4781 (2004), 10.1073/pnas.0305937101; Davidich et al., PLoS ONE 3, e1672 (2008), 10.1371/journal.pone.0001672], no or minimal changes to the wiring diagrams are necessary to formulate their dynamics in terms of the veto functions introduced here.
Streamflow forecasting using functional regression
Masselot, Pierre; Dabo-Niang, Sophie; Chebana, Fateh; Ouarda, Taha B. M. J.
2016-07-01
Streamflow, as a natural phenomenon, is continuous in time and so are the meteorological variables which influence its variability. In practice, it can be of interest to forecast the whole flow curve instead of points (daily or hourly). To this end, this paper introduces the functional linear models and adapts it to hydrological forecasting. More precisely, functional linear models are regression models based on curves instead of single values. They allow to consider the whole process instead of a limited number of time points or features. We apply these models to analyse the flow volume and the whole streamflow curve during a given period by using precipitations curves. The functional model is shown to lead to encouraging results. The potential of functional linear models to detect special features that would have been hard to see otherwise is pointed out. The functional model is also compared to the artificial neural network approach and the advantages and disadvantages of both models are discussed. Finally, future research directions involving the functional model in hydrology are presented.
Elementary Functions, Student's Text, Unit 21.
Allen, Frank B.; And Others
Unit 21 in the SMSG secondary school mathematics series is a student text covering the following topics in elementary functions: functions, polynomial functions, tangents to graphs of polynomial functions, exponential and logarithmic functions, and circular functions. Appendices discuss set notation, mathematical induction, significance of…
Network-based functional enrichment
Directory of Open Access Journals (Sweden)
Poirel Christopher L
2011-11-01
Full Text Available Abstract Background Many methods have been developed to infer and reason about molecular interaction networks. These approaches often yield networks with hundreds or thousands of nodes and up to an order of magnitude more edges. It is often desirable to summarize the biological information in such networks. A very common approach is to use gene function enrichment analysis for this task. A major drawback of this method is that it ignores information about the edges in the network being analyzed, i.e., it treats the network simply as a set of genes. In this paper, we introduce a novel method for functional enrichment that explicitly takes network interactions into account. Results Our approach naturally generalizes Fisher’s exact test, a gene set-based technique. Given a function of interest, we compute the subgraph of the network induced by genes annotated to this function. We use the sequence of sizes of the connected components of this sub-network to estimate its connectivity. We estimate the statistical significance of the connectivity empirically by a permutation test. We present three applications of our method: i determine which functions are enriched in a given network, ii given a network and an interesting sub-network of genes within that network, determine which functions are enriched in the sub-network, and iii given two networks, determine the functions for which the connectivity improves when we merge the second network into the first. Through these applications, we show that our approach is a natural alternative to network clustering algorithms. Conclusions We presented a novel approach to functional enrichment that takes into account the pairwise relationships among genes annotated by a particular function. Each of the three applications discovers highly relevant functions. We used our methods to study biological data from three different organisms. Our results demonstrate the wide applicability of our methods. Our algorithms are
Nitrogenase structure and function relationships by density functional theory.
Harris, Travis V; Szilagyi, Robert K
2011-01-01
Modern density functional theory has tremendous potential with matching popularity in metalloenzymology to reveal the unseen atomic and molecular details of structural data, spectroscopic measurements, and biochemical experiments by providing insights into unobservable structures and states, while also offering theoretical justifications for observed trends and differences. An often untapped potential of this theoretical approach is to bring together diverse experimental structural and reactivity information and allow for these to be critically evaluated at the same level. This is particularly applicable for the tantalizingly complex problem of the structure and molecular mechanism of biological nitrogen fixation. In this chapter we provide a review with extensive practical details of the compilation and evaluation of experimental data for an unbiased and systematic density functional theory analysis that can lead to remarkable new insights about the structure-function relationships of the iron-sulfur clusters of nitrogenase.
Fold modulating function: Bacterial toxins to functional amyloids
Directory of Open Access Journals (Sweden)
Adnan Khawaja Syed
2014-08-01
Full Text Available Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is well known that environmental factors control toxin expression, however recent work suggests that some bacteria manipulate the fold of these protein toxins to control their function. The β-sheet rich amyloid fold is a highly stable ordered aggregate that many toxins form in response to specific environmental conditions. When in the amyloid state, toxins become inert, losing the cytolytic activity they display in the soluble form. Emerging evidence suggest that some amyloids function as toxin storage systems until they are again needed, while other bacteria utilize amyloids as a structural matrix component of biofilms. This amyloid matrix component facilitates resistance to biofilm disruptive challenges. The bacterial amyloids discussed in this review reveal an elegant system where changes in protein fold and solubility dictate the function of proteins in response to the environment.
Cephalometric analysis for functional occlusion
Directory of Open Access Journals (Sweden)
Ashok Karad
2016-01-01
Full Text Available Background: Various elements contributing to good functional occlusion have not been clearly assessed with cephalometrics for the diagnosis of functional problems and their application in clinical practice. The aim of this study, therefore, was to analyze different components of functional occlusion to formulate concise functional cephalometric analysis. Materials and Methods: Eighty-two cases (38 males and 44 females, with class I occlusion and balanced facial profile, were examined based on the selection criteria, and cephalograms were taken in natural head position. All the radiographs were then analyzed using various functional parameters. Results: The mean values of condylar path angle and incisal path angle were 55.83° and 65.67°, respectively, with large deviations. However, both showed positive correlation. The value of the angle of long axis of mandibular incisor with respect to the line joining center of condyle and lower incisor tip was 88.04°. Moreover, the angle between the occlusal plane and horizontal plane was 12.88°. In vertical plane, lower face height (LFH was found to be slightly less than the upper face height. Maxilla contributed around 45% of the LFH while mandible formed about 60%. Furthermore, upper alveolar component (maxillary alveolar height formed more than half of the maxilla (53.79% whereas lower alveolar component (mandibular alveolar height was 74.8% of the mandible. Conclusion: This study has analyzed various components of functional occlusion and formulated a concise functional cephalometric analysis for diagnosis, treatment planning, and assessment of treatment results.
Functional brain imaging across development.
Rubia, Katya
2013-12-01
The developmental cognitive neuroscience literature has grown exponentially over the last decade. This paper reviews the functional magnetic resonance imaging (fMRI) literature on brain function development of typically late developing functions of cognitive and motivation control, timing and attention as well as of resting state neural networks. Evidence shows that between childhood and adulthood, concomitant with cognitive maturation, there is progressively increased functional activation in task-relevant lateral and medial frontal, striatal and parieto-temporal brain regions that mediate these higher level control functions. This is accompanied by progressively stronger functional inter-regional connectivity within task-relevant fronto-striatal and fronto-parieto-temporal networks. Negative age associations are observed in earlier developing posterior and limbic regions, suggesting a shift with age from the recruitment of "bottom-up" processing regions towards "top-down" fronto-cortical and fronto-subcortical connections, leading to a more mature, supervised cognition. The resting state fMRI literature further complements this evidence by showing progressively stronger deactivation with age in anti-correlated task-negative resting state networks, which is associated with better task performance. Furthermore, connectivity analyses during the resting state show that with development increasingly stronger long-range connections are being formed, for example, between fronto-parietal and fronto-cerebellar connections, in both task-positive networks and in task-negative default mode networks, together with progressively lesser short-range connections, suggesting progressive functional integration and segregation with age. Overall, evidence suggests that throughout development between childhood and adulthood, there is progressive refinement and integration of both task-positive fronto-cortical and fronto-subcortical activation and task-negative deactivation, leading to
[Functional cramps or functional dystonias in writers and musicians].
Chamagne, P
1986-01-01
The clinical evaluation in the "dystonies of function" or "impaired dexterity" reveals certain physical anomalies which either appear spontaneously or are triggered by specific tests: abnormal postures involving the trunck, head, and upper limb. During the professional gesture the physiological "pulley effect" on flexor tendons is accompanied with an interference effect produced by the displacement of the segments; this, adds up to an unbalance of the digital kinetic chain, building a locked functional system. The antagonist muscles begin to supply the deficiency of the agonist muscles. In addition, patients with a characteristic psychological ground suffer a more acute "disorganization" or a performing career.
Whitenack, Daniel L; Wasserman, Adam
2012-04-28
Aspects of density functional resonance theory (DFRT) [D. L. Whitenack and A. Wasserman, Phys. Rev. Lett. 107, 163002 (2011)], a recently developed complex-scaled version of ground-state density functional theory (DFT), are studied in detail. The asymptotic behavior of the complex density function is related to the complex resonance energy and system's threshold energy, and the function's local oscillatory behavior is connected with preferential directions of electron decay. Practical considerations for implementation of the theory are addressed including sensitivity to the complex-scaling parameter, θ. In Kohn-Sham DFRT, it is shown that almost all θ-dependence in the calculated energies and lifetimes can be extinguished via use of a proper basis set or fine grid. The highest occupied Kohn-Sham orbital energy and lifetime are related to physical affinity and width, and the threshold energy of the Kohn-Sham system is shown to be equal to the threshold energy of the interacting system shifted by a well-defined functional. Finally, various complex-scaling conditions are derived which relate the functionals of ground-state DFT to those of DFRT via proper scaling factors and a non-Hermitian coupling-constant system.
Functional Prions in the Brain.
Rayman, Joseph B; Kandel, Eric R
2017-01-03
Prions are proteins that can adopt self-perpetuating conformations and are traditionally regarded as etiological agents of infectious neurodegenerative diseases in humans, such as Creutzfeldt-Jakob disease, kuru, and transmissible encephalopathies. More recently, a growing consensus has emerged that prion-like, self-templating mechanisms also underlie a variety of neurodegenerative disorders, including amyotrophic lateral sclerosis, Alzheimer's disease, and Huntington's disease. Perhaps most surprising, not all prion-like aggregates are associated with pathological changes. There are now several examples of prion-like proteins in mammals that serve positive biological functions in their aggregated state. In this review, we discuss functional prions in the nervous system, with particular emphasis on the cytoplasmic polyadenylation element-binding protein (CPEB) and the role of its prion-like aggregates in synaptic plasticity and memory. We also mention a more recent example of a functional prion-like protein in the brain, TIA-1, and its role during stress. These studies of functional prion-like proteins have provided a number of generalizable insights on how prion-based protein switches may operate to serve physiological functions in higher eukaryotes.
Functional theories of thermoelectric phenomena
Eich, F. G.; Di Ventra, M.; Vignale, G.
2017-02-01
We review the progress that has been recently made in the application of time-dependent density functional theory to thermoelectric phenomena. As the field is very young, we emphasize open problems and fundamental issues. We begin by introducing the formal structure of thermal density functional theory, a density functional theory with two basic variables—the density and the energy density—and two conjugate fields—the ordinary scalar potential and Luttinger’s thermomechanical potential. The static version of this theory is contrasted with the familiar finite-temperature density functional theory, in which only the density is a variable. We then proceed to constructing the full time-dependent non equilibrium theory, including the practically important Kohn-Sham equations that go with it. The theory is shown to recover standard results of the Landauer theory for thermal transport in the steady state, while showing greater flexibility by allowing a description of fast thermal response, temperature oscillations and related phenomena. Several results are presented here for the first time, i.e. the proof of invertibility of the thermal response function in the linear regime, the full expression of the thermal currents in the presence of Luttinger’s thermomechanical potential, an explicit prescription for the evaluation of the Kohn-Sham potentials in the adiabatic local density approximation, a detailed discussion of the leading dissipative corrections to the adiabatic local density approximation and the thermal corrections to the resistivity that follow from it.
GRID INFORMATION SECURITY FUNCTIONAL REQUIREMENT
Directory of Open Access Journals (Sweden)
Amy Poh Ai Ling
2011-07-01
Full Text Available This paper describes the background of smart information infrastructure and the needs for smart grid information security. It introduces the conceptual analysis to the methodology with the application ofhermeneutic circle and information security functional requirement identification. Information security for the grid market cover matters includes automation and communications industry that affects the operation of electric power systems and the functioning of the utilities that manage them and its awareness of this information infrastructure has become critical to the reliability of the power system. Community benefits from of cost savings, flexibility and deployment along with the establishment of wireless communications. However, concern revolves around the security protections for easily accessible devices such as the smart meter and the related communications hardware. On the other hand, the changing points between traditional versus smart grid networking trend and the information security importance on the communication field reflects the criticality of grid information security functional requirement identification. The goal of this paper is to identify the functional requirement and relate its significance addresses to the consumer requirement of an information security of a smart grid. Vulnerabilities may bring forth possibility for an attacker to penetrate a network, make headway admission to control software, alter it to load conditions that destabilize the grid in unpredictable ways. Focusing on the grid information security functional requirement is stepping ahead in developing consumer trust and satisfaction towardsmart grid completeness.
``Backpack'' Functionalized Living Immune Cells
Swiston, Albert; Um, Soong Ho; Irvine, Darrell; Cohen, Robert; Rubner, Michael
2009-03-01
We demonstrate that functional polymeric ``backpacks'' built from polyelectrolyte multilayers (PEMs) can be attached to a fraction of the surface area of living, individual lymphocytes. Backpacks containing fluorescent polymers, superparamagnetic nanoparticles, and commercially available quantum dots have been attached to B and T-cells, which may be spatially manipulated using a magnetic field. Since the backpack does not occlude the entire cellular surface from the environment, this technique allows functional synthetic payloads to be attached to a cell that is free to perform its native functions, thereby synergistically utilizing both biological and synthetic functionalities. For instance, we have shown that backpack-modified T-cells are able to migrate on surfaces for several hours following backpack attachment. Possible payloads within the PEM backpack include drugs, vaccine antigens, thermally responsive polymers, nanoparticles, and imaging agents. We will discuss how this approach has broad potential for applications in bioimaging, single-cell functionalization, immune system and tissue engineering, and cell-based therapeutics where cell-environment interactions are critical.
Bernoulli numbers and zeta functions
Arakawa, Tsuneo; Kaneko, Masanobu
2014-01-01
Two major subjects are treated in this book. The main one is the theory of Bernoulli numbers and the other is the theory of zeta functions. Historically, Bernoulli numbers were introduced to give formulas for the sums of powers of consecutive integers. The real reason that they are indispensable for number theory, however, lies in the fact that special values of the Riemann zeta function can be written by using Bernoulli numbers. This leads to more advanced topics, a number of which are treated in this book: Historical remarks on Bernoulli numbers and the formula for the sum of powers of consecutive integers; a formula for Bernoulli numbers by Stirling numbers; the Clausen–von Staudt theorem on the denominators of Bernoulli numbers; Kummer's congruence between Bernoulli numbers and a related theory of p-adic measures; the Euler–Maclaurin summation formula; the functional equation of the Riemann zeta function and the Dirichlet L functions, and their special values at suitable integers; various formulas of ...
Functionalized carbon nanotubes: biomedical applications
Directory of Open Access Journals (Sweden)
Vardharajula S
2012-10-01
Full Text Available Sandhya Vardharajula,1 Sk Z Ali,2 Pooja M Tiwari,1 Erdal Eroğlu,1 Komal Vig,1 Vida A Dennis,1 Shree R Singh11Center for NanoBiotechnology and Life Sciences Research, Alabama State University, Montgomery, AL, USA; 2Department of Microbiology, Osmania University, Hyderabad, IndiaAbstract: Carbon nanotubes (CNTs are emerging as novel nanomaterials for various biomedical applications. CNTs can be used to deliver a variety of therapeutic agents, including biomolecules, to the target disease sites. In addition, their unparalleled optical and electrical properties make them excellent candidates for bioimaging and other biomedical applications. However, the high cytotoxicity of CNTs limits their use in humans and many biological systems. The biocompatibility and low cytotoxicity of CNTs are attributed to size, dose, duration, testing systems, and surface functionalization. The functionalization of CNTs improves their solubility and biocompatibility and alters their cellular interaction pathways, resulting in much-reduced cytotoxic effects. Functionalized CNTs are promising novel materials for a variety of biomedical applications. These potential applications are particularly enhanced by their ability to penetrate biological membranes with relatively low cytotoxicity. This review is directed towards the overview of CNTs and their functionalization for biomedical applications with minimal cytotoxicity.Keywords: carbon nanotubes, cytotoxicity, functionalization, biomedical applications
Mitochondria: isolation, structure and function.
Picard, Martin; Taivassalo, Tanja; Gouspillou, Gilles; Hepple, Russell T
2011-09-15
Mitochondria are complex organelles constantly undergoing processes of fusion and fission, processes that not only modulate their morphology, but also their function. Yet the assessment of mitochondrial function in skeletal muscle often involves mechanical isolation of the mitochondria, a process which disrupts their normally heterogeneous branching structure and yields relatively homogeneous spherical organelles. Alternatively, methods have been used where the sarcolemma is permeabilized and mitochondrial morphology is preserved, but both methods face the downside that they remove potential influences of the intracellular milieu on mitochondrial function. Importantly, recent evidence shows that the fragmented mitochondrial morphology resulting from routine mitochondrial isolation procedures used with skeletal muscle alters key indices of function in a manner qualitatively similar to mitochondria undergoing fission in vivo. Although these results warrant caution when interpreting data obtained with mitochondria isolated from skeletal muscle, they also suggest that isolated mitochondrial preparations might present a useful way of interrogating the stress resistance of mitochondria. More importantly, these new findings underscore the empirical value of studying mitochondrial function in minimally disruptive experimental preparations. In this review, we briefly discuss several considerations and hypotheses emerging from this work.
Functional and motor gastrointestinal disorders.
Mearin, Fermín; Rey, Enrique; Balboa, Agustín
2016-09-01
This article discusses the most interesting presentations at Digestive Disease Week, held in San Diego, in the field of functional and motor gastrointestinal disorders. One of the most important contributions was undoubtedly the presentation of the new Rome IV diagnostic criteria for functional gastrointestinal disorders. We therefore devote some space in this article to explaining these new criteria in the most common functional disorders. In fact, there has already been discussion of data comparing Rome IV and Rome III criteria in the diagnosis of irritable bowel syndrome, confirming that the new criteria are somewhat more restrictive. From the physiopathological point of view, several studies have shown that the aggregation of physiopathological alterations increases symptom severity in distinct functional disorders. From the therapeutic point of view, more data were presented on the efficacy of acotiamide and its mechanisms of action in functional dyspepsia, the safety and efficacy of domperidone in patients with gastroparesis, and the efficacy of linaclotide both in irritable bowel syndrome and constipation. In irritable bowel syndrome, more data have come to light on the favourable results of a low FODMAP diet, with emphasis on its role in modifying the microbiota. Finally, long-term efficacy data were presented on the distinct treatment options in achalasia.
Melatonin, immune function and aging
Directory of Open Access Journals (Sweden)
Perumal SR Pandi
2005-11-01
Full Text Available Abstract Aging is associated with a decline in immune function (immunosenescence, a situation known to correlate with increased incidence of cancer, infectious and degenerative diseases. Innate, cellular and humoral immunity all exhibit increased deterioration with age. A decrease in functional competence of individual natural killer (NK cells is found with advancing age. Macrophages and granulocytes show functional decline in aging as evidenced by their diminished phagocytic activity and impairment of superoxide generation. There is also marked shift in cytokine profile as age advances, e.g., CD3+ and CD4+ cells decline in number whereas CD8+ cells increase in elderly individuals. A decline in organ specific antibodies occurs causing reduced humoral responsiveness. Circulating melatonin decreases with age and in recent years much interest has been focused on its immunomodulatory effect. Melatonin stimulates the production of progenitor cells for granulocytes-macrophages. It also stimulates the production of NK cells and CD4+ cells and inhibits CD8+ cells. The production and release of various cytokines from NK cells and T-helper lymphocytes also are enhanced by melatonin. Melatonin presumably regulates immune function by acting on the immune-opioid network, by affecting G protein-cAMP signal pathway and by regulating intracellular glutathione levels. Melatonin has the potential therapeutic value to enhance immune function in aged individuals and in patients in an immunocompromised state.
Aging and functional brain networks
Energy Technology Data Exchange (ETDEWEB)
Tomasi D.; Tomasi, D.; Volkow, N.D.
2011-07-11
Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the 'default-mode' network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging would be associated with a decline of short- and long-range functional connectivity density (FCD) hubs in the DMN. To test this hypothesis, we evaluated resting-state data sets corresponding to 913 healthy subjects from a public magnetic resonance imaging database using functional connectivity density mapping (FCDM), a voxelwise and data-driven approach, together with parallel computing. Aging was associated with pronounced long-range FCD decreases in DMN and dorsal attention network (DAN) and with increases in somatosensory and subcortical networks. Aging effects in these networks were stronger for long-range than for short-range FCD and were also detected at the level of the main functional hubs. Females had higher short- and long-range FCD in DMN and lower FCD in the somatosensory network than males, but the gender by age interaction effects were not significant for any of the networks or hubs. These findings suggest that long-range connections may be more vulnerable to aging effects than short-range connections and that, in addition to the DMN, the DAN is also sensitive to aging effects, which could underlie the deterioration of attention processes that occurs with aging.
Functional food science and behaviour and psychological functions.
Bellisle, F; Blundell, J E; Dye, L; Fantino, M; Fern, E; Fletcher, R J; Lambert, J; Roberfroid, M; Specter, S; Westenhöfer, J; Westerterp-Plantenga, M S
1998-08-01
The impact of ingesting various foods on psychological and behavioural functions is a topic of both interest and concern to the general public. In this article, the scientific literature concerning demonstrated cause-and-effect relationships is reviewed, beginning with methodological considerations specific to the quantification of particular behaviours and psychological events. The essential function of food is to satisfy hunger and the need for essential nutrients. The contributions of macronutrients to appetite and satiety are described, as well as their impact on metabolism and energy balance. Functional properties of macronutrient substitutes (high-intensity sweeteners, fat replacers) and flavour enhancers are examined in relation to their contribution to hunger, satiety, and energy balance. The effects of foods and individual nutrients on the performance of diverse psychomotor tasks are studied with consideration given to the various validated quantitative tools used to assess behaviour. The effects of food components on activation, sedation, and affective states such as dysphoria are also reviewed, with special attention given to brain function and neuroactive substances such as serotonin and the endorphins. The case of hyperactivity in children is given special emphasis with reference to the potential influence of sugar and food additives. Safety issues related to food constituents and additives are discussed. Finally, a set of criteria is proposed for the evaluation and elaboration of studies in the behavioural and psychological fields, along with suggestions for future research.
Apathy, cognitive function and motor function in Alzheimer's disease
Directory of Open Access Journals (Sweden)
Salma S. Soleman Hernandez
Full Text Available Abstract The aims of this study were to characterize the presence of apathy in patients with AD, determine the relationship between apathy, motor function and cognitive function, and to verify differences among patients stratified by level of apathy in relation to cognitive and motor abilities. Methods: A cross-sectional study was conducted of 37 patients with AD. The following tests were used: MoCA, the Frontal Assessment Battery, Verbal Fluency, Clock Drawing Test, Andreotti & Okuma Battery Tests, Sit and Reach, Resistance of Upper Limbs - AAHPERD Battery Test, Sit and Lift Chair and the Apathy domain of the Neuropsychiatric Inventory. After verifying the normality of the data distribution, comparisons were made using Student's t-test and the U Mann Whitney test; relationships were also assessed using Pearson's and Spearman's correlation coefficients. All analyses were considered to be statistically significant at a p-value of 0.05. Results: 46% of participants in this study showed mild symptoms of apathy. Significant and weak associations were found (p=0.04 between apathy and the attention domain on the MoCA and between apathy and the Walk Test. Analysis of differences in cognitive and motor functions according to participants' level of apathy revealed no significant differences for any of the variables. Conclusion: Apathy was reflected in attention and the Walk Test, suggesting these variables may be related to cognitive and functional decline in AD patients.
A partition function approximation using elementary symmetric functions.
Directory of Open Access Journals (Sweden)
Ramu Anandakrishnan
Full Text Available In statistical mechanics, the canonical partition function [Formula: see text] can be used to compute equilibrium properties of a physical system. Calculating [Formula: see text] however, is in general computationally intractable, since the computation scales exponentially with the number of particles [Formula: see text] in the system. A commonly used method for approximating equilibrium properties, is the Monte Carlo (MC method. For some problems the MC method converges slowly, requiring a very large number of MC steps. For such problems the computational cost of the Monte Carlo method can be prohibitive. Presented here is a deterministic algorithm - the direct interaction algorithm (DIA - for approximating the canonical partition function [Formula: see text] in [Formula: see text] operations. The DIA approximates the partition function as a combinatorial sum of products known as elementary symmetric functions (ESFs, which can be computed in [Formula: see text] operations. The DIA was used to compute equilibrium properties for the isotropic 2D Ising model, and the accuracy of the DIA was compared to that of the basic Metropolis Monte Carlo method. Our results show that the DIA may be a practical alternative for some problems where the Monte Carlo method converge slowly, and computational speed is a critical constraint, such as for very large systems or web-based applications.
EMERGENCE FROM LOCAL EVALUATION FUNCTION
Institute of Scientific and Technical Information of China (English)
HAN Jing; CAI Qingsheng
2003-01-01
This paper presents a new look on emergence from the aspect of locality and globality of evaluation functions for solving traditional computer problems. We first translate the Constraint Satisfaction Problem (CSP) into the multi-agent system, and then show how a global solution emerges from the system in which every agent uses a local evaluation function to decide its action, while comparing to other traditional algorithms, such as Local search and Simulated Annealing which use global evaluation functions. We also give some computer experimental results on large-scale N-queen problems and k-Coloring problems, and show that emergence only depends on problem instance, not details of agent settings, i.e. in some CSPs, the system can self-organize to a global solution, but can not in some other CSPs no matter what settings of agents have.
Estimating Functions and Semiparametric Models
DEFF Research Database (Denmark)
Labouriau, Rodrigo
1996-01-01
The thesis is divided in two parts. The first part treats some topics of the estimation theory for semiparametric models in general. There the classic optimality theory is reviewed and exposed in a suitable way for the further developments given after. Further the theory of estimating functions...... contained in this part of the thesis constitutes an original contribution. There can be found the detailed characterization of the class of regular estimating functions, a calculation of efficient regular asymptotic linear estimating sequences (\\ie the classical optimality theory) and a discussion...... of the attainability of the bounds for the concentration of regular asymptotic linear estimating sequences by estimators derived from estimating functions. The main class of models considered in the second part of the thesis (chapter 5) are constructed by assuming that the expectation of a number of given square...
Functional foods: an ecologic perspective.
Marriott, B M
2000-06-01
A functional food is defined as any food or food ingredient that may provide a health benefit beyond that conferred by the nutrients the food contains. As nutrition scientists move into this arena, they must build on the wealth of information that already exists in plant biology. In particular, the evolutionary and physiologic bases for the production of secondary plant chemicals in plants must be considered in order to plan meaningful experiments for testing the functionality of these chemical compounds for humans. One problem that may arise is that in using the term functional food, the meaning may be lost in the continued proliferation of related terms used in product marketing. The new National Institutes of Health Office of Dietary Supplements addressed some of these issues as it developed the operating definitions described in this report.
Functionally Graded Mo sintered steels
Directory of Open Access Journals (Sweden)
Manuel Cisneros-Belmonte
2016-12-01
Full Text Available Functionally graded materials (FGM, the multi-materials, strive to satisfy the numerous requirements demanded of parts in a given combination of compositions and microstructures. The required material compatibility lead the manufacturing process and the achieving of an interface, not always diffuse. Powder metallurgy is one of the techniques used in manufacturing functionally graded materials, in particular the compaction matrix of the possible techniques for forming these materials. In this paper, a process of forming a functionally graded steel based on the use of a high molybdenum steel with cooper and other steel with copper, without molybdenum, is proposed with the aim of concentrating this element to the surface of the workpiece, increasing the mechanical strength. The study is completed with the evaluation of physical properties (density and porosity distribution, mechanical properties (hardness, tensile strength and elongation and microstructural analysis by optical and scanning electron microscopy.
Function Spaces for Liquid Crystals
Bedford, Stephen
2016-02-01
We consider the relationship between three continuum liquid crystal theories: Oseen-Frank, Ericksen and Landau-de Gennes. It is known that the function space is an important part of the mathematical model and by considering various function space choices for the order parameters s, n, and Q, we establish connections between the variational formulations of these theories. We use these results to justify a version of the Oseen-Frank theory using special functions of bounded variation. This proposed model can describe both orientable and non-orientable defects. Finally we study a number of frustrated nematic and cholesteric liquid crystal systems and show that the model predicts the existence of point and surface discontinuities in the director.
Ruzsa's Constant on Additive Functions
Institute of Scientific and Technical Information of China (English)
Jin Hui FANG; Yong Gao CHEN
2013-01-01
A function f:N → R is called additive if f(mn) =f(m)+f(n) for all m,n with (m,n) =1.Let μ(x) =maxn≤x(f(n)-f(n + 1)) and v(x) =maxn≤x(f(n + 1)-f(n)).In 1979,Ruzsa proved that there exists a constant c such that for any additive function f,μ(x) ≤ cv(x2) + cf,where cf is a constant depending only on f.Denote by Raf the least such constant c.We call Raf Ruzsa's constant on additive functions.In this paper,we prove that Raf ≤ 20.
Statistical modelling with quantile functions
Gilchrist, Warren
2000-01-01
Galton used quantiles more than a hundred years ago in describing data. Tukey and Parzen used them in the 60s and 70s in describing populations. Since then, the authors of many papers, both theoretical and practical, have used various aspects of quantiles in their work. Until now, however, no one put all the ideas together to form what turns out to be a general approach to statistics.Statistical Modelling with Quantile Functions does just that. It systematically examines the entire process of statistical modelling, starting with using the quantile function to define continuous distributions. The author shows that by using this approach, it becomes possible to develop complex distributional models from simple components. A modelling kit can be developed that applies to the whole model - deterministic and stochastic components - and this kit operates by adding, multiplying, and transforming distributions rather than data.Statistical Modelling with Quantile Functions adds a new dimension to the practice of stati...
Green function for hyperbolic media
Potemkin, Andrey S; Belov, Pavel A; Kivshar, Yuri S
2012-01-01
We revisit the problem of the electromagnetic Green function for homogeneous hyperbolic media, where longitudinal and transverse components of the dielectric permittivity tensor have different signs. We analyze the dipole emission patterns for both dipole orientations with respect to the symmetry axis and for different signs of dielectric constants, and show that the emission pattern is highly anisotropic and has a characteristic cross-like shape: the waves are propagating within a certain cone and are evanescent outside this cone. We demonstrate the coexistence of the cone-like pattern due to emission of the extraordinary TM-polarized waves and elliptical pattern due to emission of ordinary TE-polarized waves. We find a singular complex term in the Green function, proportional to the $\\delta-$function and governing the photonic density of states and Purcell effect in hyperbolic media.
SCATTERING FUNCTION OF POLYMER BLENDS
Institute of Scientific and Technical Information of China (English)
Lin-ping Ke; Mei-li Guo; De-lu Zhao
2004-01-01
For a system of flexible polymer molecules, the concepts of two concentrations, namely the segmental and the molecular concentrations, have been proposed in this paper. The former is equivalent to the volume fraction. The latter can be defined as the number of the gravity centers of macromolecules in a unit volume. The two concentrations should be correlated with each other by the conformational function of the polymer chain and should be discussed in different thermodynamic equations. On the basis of these concepts it has been proved that the Flory-Huggins entropy of mixing should be the result of the mixing "ideal gases of the gravity centers of macromolecules". The general correlation between the free energy of mixing and the scattering function (structural factor) of polymer blends has been studied based on the general fluctuation theory. When the Flory-Huggins free energy of mixing is adopted, the de Gennes scattering function of a polymer blend can be derived.
Iacovacci, Jacopo; Arenas, Alex; Bianconi, Ginestra
2016-01-01
Recently it has been recognized that many complex social, technological and biological networks have a multilayer nature and can be described by multiplex networks. Multiplex networks are formed by a set of nodes connected by links having different connotations forming the different layers of the multiplex. Characterizing the centrality of the nodes in a multiplex network is a challenging task since the centrality of the node naturally depends on the importance associated to links of a certain type. Here we propose to assign to each node of a multiplex network a centrality called Functional Multiplex PageRank that is a function of the weights given to every different pattern of connections (multilinks) existent in the multiplex network between any two nodes. Since multilinks distinguish all the possible ways in which the links in different layers can overlap, the Functional Multiplex PageRank can describe important non-linear effects when large relevance or small relevance is assigned to multilinks with overl...