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Sample records for areva nc cadarache

  1. ITER at Cadarache; ITER a Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-06-15

    This public information document presents the ITER project (International Thermonuclear Experimental Reactor), the definition of the fusion, the international cooperation and the advantages of the project. It presents also the site of Cadarache, an appropriate scientifical and economical environment. The last part of the documentation recalls the historical aspect of the project and the today mobilization of all partners. (A.L.B.)

  2. Decision no. 2011-DC-0217 of the French nuclear safety authority from May 5, 2011, ordering the AREVA NC group to proceed to a complementary safety evaluation of some of its basic nuclear facilities in the eyes of the Fukushima Daiichi nuclear power plant accident; Decision no. 2011-DC-0217 de l'Autorite de surete nucleaire du 5 mai 2011 prescrivant a AREVA NC de proceder a une evaluation complementaire de la surete de certaines de ses installations nucleaires de base au regard de l'accident survenu a la centrale nucleaire de Fukushima Daiichi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    As a consequence of the accident of the Fukushima Daiichi nuclear power plant (Japan), the French Prime Minister entrusted the French nuclear safety authority (ASN) with the mission to carry out a safety analysis re-evaluation of the French nuclear facilities, and in particular the nuclear power plants. A decision has been addressed by the ASN to each nuclear operator with the specifications of this safety re-evaluation analysis and the list of facilities in concern. This document is the decision addressed to the AREVA NC group. (J.S.)

  3. Areva, annual report 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This annual report contains information on AREVA objectives, prospects and strategies, particularly in chapters 4 and 7. This information is a not meant as a presentation of past performance data and should not be interpreted as a guarantee that events or data set forth herein are assured or that objectives will be met. Forward looking statements made in this document also address known and unknown risks, uncertainties and other factors that could, were they to translate into fact, cause AREVA future financial performance, operating performance and production to differ significantly from the objectives presented or suggested herein. Those factors include, in particular, changes in international, economic or market conditions, as well as risk factors presented in Section 4.14.3. Neither AREVA nor the AREVA group is committing to updating forward looking statements or information contained in the annual report. This annual report contains information on the markets, market shares and competitive position of the AREVA group. Unless otherwise indicated, all historical data and forward looking information are based on Group estimates (source: AREVA) and are provided as examples only. To AREVA knowledge, no report is available on the AREVA group markets that is sufficiently complete or objective to serve as a sole reference source. The AREVA group developed estimates based on several sources, including in-house studies and reports, statistics provided by international organizations and professional associations, data published by competitors and information collected by AREVA subsidiaries. The main sources, studies and reports used include (i) the International Atomic Energy Agency (IAEA), the International Energy Agency (IEA), the World Nuclear Association (WNA), the Nuclear Energy Institute (NEA), Nuclear Assurance Corporation (NAC), the European Atomic Energy Community (Euratom) and the Commissariat a l'Energie Atomique (CEA) for the nuclear business; and (ii

  4. Tuumaenergeetikale tasub panustada Areva kaudu / Tarmo Tanilas

    Index Scriptorium Estoniae

    Tanilas, Tarmo

    2009-01-01

    Suurim tuumaenergia infrastruktuuride tootja, Prantsuse energeetikafirma Areva, sobib pikaajalisi invetseerimistrende otsivale investorile. Tabel: Areva turuosad tuumaenergia tootmisahelas. Graafik: Areva aktsia hind

  5. AREVA group overview; Presentation du groupe AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-02-08

    This document presents the Group Areva, a world nuclear industry leader, from a financial holding company to an industrial group, operating in two businesses: the nuclear energy and the components. The structure and the market of the group are discussed, as the financial assets. (A.L.B.)

  6. Areva, reference document 2006; Areva, document de reference 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains information on the markets, market shares and competitive position of the AREVA group. Content: - 1 Person responsible for the reference document and persons responsible for auditing the financial statements; - 2 Information pertaining to the transaction (Not applicable); - 3 General information on the company and its share capital: Information on AREVA, on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; - 4 Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts, The principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development programs, intellectual property and trademarks, Risk and insurance; - 5 Assets - Financial position - Financial performance: Analysis of and comments on the group's financial position and performance, 2006 Human Resources Report, Environmental Report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA financial statements, Notes to the corporate financial statements; 6 - Corporate Governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Combined General Meeting of Shareholders of May 3, 2007; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2006, Outlook; 8 - Glossary; 9 - Table of concordance.

  7. Areva in Niger

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-02-01

    Niger is the second poorest country in the world but it has natural resources underground in the form of uranium ores deposits. This uranium is currently mined by two companies incorporated under Nigerian law: Somair and Cominak, operated by the principal shareholder Areva (through its subsidiary Cogema). After a presentation of Somair and Cominak key figures, this document details the working conditions and radiological protection, the environmentally friendly operations, the production traceability, the local economic development, the strengthening of the health care system and the development of the infrastructure. (A.L.B.)

  8. Areva 2005 annual report; Areva rapport annuel 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This annual report contains information on AREVA's objectives, prospects and strategies, particularly in Chapters 4 and 7, as well as contains information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the annual report and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction; 3 - General information on the company and share capital: Information on AREVA, Information on share capital and voting rights, Investment certificate trading, Dividends, Organizational chart of the AREVA group, Equity interests, Shareholders' agreements; 4 - Information on company operations, 5 - New developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, AREVA group energy businesses, Front End Division, Reactors and Services Division, Back End Division, Transmission and Distribution Division, Major Contracts, The Group's principal sites, AREVA's customers and suppliers, Human resources, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development, intellectual property and brand name programs, Risk and insurance; 6 - Assets - Financial position - financial performance: Analysis of and comments on the Group's financial position and performance, Human Resources report 2005, Environmental report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA Financial statements 2005, Notes to the corporate financial statements; 7 - Corporate governance: Composition and functioning of administrative bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual General Meeting of Shareholders of May 2, 2006; 8 - Recent developments and outlook: Events subsequent to year-end closing for 2005, Outlook.

  9. Areva reference document 2007; Areva document de reference 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains also information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the reference document and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction (not applicable); 3 - General information on the company and its share capital: Information on Areva, Information on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; 4 - Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts 140 Principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and Development programs, Intellectual Property and Trademarks, Risk and insurance; 5 - Assets financial position financial performance: Analysis of and comments on the group's financial position and performance, Human Resources report, Environmental report, Consolidated financial statements 2007, Notes to the consolidated financial statements, Annual financial statements 2007, Notes to the corporate financial statements; 6 - Corporate governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Ordinary General Meeting of Shareholders of April 17, 2008; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2007, Outlook; Glossary; table of

  10. Report transparency and nuclear safety 2007 CEA Cadarache; Rapport transparence et securite nucleaire 2007 CEA Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report presents the activities of the CEA Center of Cadarache for the year 2007. The actions concerning the safety, the radiation protection, the significant events, the release control and the environmental impacts and the wastes stored on the center are discussed. More especially the report discusses the beginning of the RJH reactor construction, the fourth generation reactors research programs, the implementing of la Rotonde the new radioactive wastes management installation, the renovation of the LECA. (A.L.B.)

  11. The 2003 essential. AREVA; L'essentiel 2003. AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This document presents the essential activities of the Areva Group, a world nuclear industry leader. This group proposes technological solutions to produce the nuclear energy and to transport the electric power. It develops connection systems for the telecommunication, the computers and the automotive industry. Key data on the program management, the sustainable development activities and the different divisions are provided. (A.L.B.)

  12. Areva - 2008 results: yet another year of growth for AREVA; Areva - Resultats 2008: une nouvelle annee de croissance pour AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-02-15

    This paper summarizes the 2008 financial results of the Areva group: Backlog: 48.2 billion euros, up 21.1%; Revenue: 13.2 billion euros, up 10.4%; Operating income: - Operating income excluding provision on OL3 contract in Finland: 1,166 million euros, i.e. operating margin of 8.9%; - Additional provision on OL3 contract of 749 million euros; - Operating income: 417 million euros, i.e. operating margin of 3.2%. Net income attributable to equity holders of the parent: 589 million euros, i.e. euros 16.62 per share; Net debt of 3.45 billion euros before recognition of the SIEMENS put; Dividend of euros 7.05 to be proposed during the Annual General Meeting of Shareholders of April 30, 2009. After publication of these figures Siemens announced its decision to withdraw from AREVA NP.

  13. Areva: experiences in outage services; Areva: experiencias en servicios de recarga

    Energy Technology Data Exchange (ETDEWEB)

    Wiemeier, R.; Mueller, N.; Blanco, I. J.

    2010-07-01

    As the world leader in the nuclear industry, Areva is firmly committed to the safe and reliable operation of the Spanish nuclear power plants. Following this commitment, Areva has established the subsidiary Areva NP Services Spain as a local platform to provide nuclear services for the Spanish nuclear power plants. being integrated and supported by the global Areva Group, Areva NP Services Spain is able to offer services solutions to all customers demands while maintaining close and sustainable relationships with them. This integration also allows the Spanish personnel of Areva to employ their skills by working in multinational teams in international projects. This article will present the capacities, and the most important recent national and international project performed by Areva NP Services Spain in the field of outage services. (Author)

  14. Areva. 2005 half year report; Areva. Rapport semestriel 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    With manufacturing facilities in over 40 countries and a sales network in over 100, AREVA offers customers technological solutions for nuclear power generation and electricity transmission and distribution. The group also provides interconnect systems to the telecommunications, computer and automotive markets. This half-year report of Areva group presents the key financial data of the group for the first half of 2005: 1 - Highlights of the period; 2 - Transition to the International Financial Reporting Standards: Group's application of IFRS, Impact of IAS 32 and 39 adoption on the Group's financial statements; 3 - Key data: summary data, summary data by business Division, backlog, income statement, review by business Division, cash flow statement, balance sheet items; 4 - events subsequent to the half-year-end; 5 - consolidated financial statements: statutory Auditors' report on the 2005 half-year financial statements - period from January 1 to June 30, 2005, consolidated income statement, consolidated balance sheet, consolidated cash flow statement, change in consolidated shareholders' equity, data by business Division and region, notes to the consolidated financial statements; 6 - Outlook.

  15. Sharing Experiences within AREVA D and D Project Portfolio: Four Illustrations - 13049

    Energy Technology Data Exchange (ETDEWEB)

    Chabeuf, Jean-Michel; Varet, Thierry [AREVA Site Value Development Business Unit, La Hague Site (France); AREVA Site Value Development Business Unit, La Hague Site

    2013-07-01

    Over the past ten years, AREVA has performed D and D operations on a wide range of nuclear sites, such as Marcoule and La Hague recycling plants, to Cadarache MOX fuel fabrication plant or Veurey and Annecy metallic Uranium machining plants. Each site is different from the other but some lessons can be shared through this D and D portfolio. In that respect, knowledge management is one of AREVA D and D Technical Department main missions. Four illustrations demonstrate the interest of knowledge share. Waste management is one of the key activities in D and D; It requires a specific characterization methodology, adapted logistics, and optimized waste channels, all of which have been developed over the years by AREVA teams on the site of Marcoule while they are rather new to La Hague, whose main activity remains fuel reprocessing despite the launch of UP2 400 D and D program. The transfer of know how has thus been organized over the past two years. Plasma cutting has been used extensively in Marcoule for years, while prohibited on the site of La Hague following questions raised about the risks associated wit Ruthenium sublimation. La Hague Technical Department has thus developed an experimental protocol to quantify and contain the Ruthenium risk, the result of which will then be applied to Marcoule where the Ruthenium issue has appeared in recent operations. Commissioning and operating fission products evaporators is a rather standard activity on UP2 800 and UP3, while the associated experience has been decreasing in Marcoule following final shutdown in 1998. When the French atomic Energy commission decided to build and operate a new evaporator to concentrate rinsing effluents prior to vitrification in 2009, AREVA La Hague operators were mobilized to test and commission the new equipment, and train local operators. Concrete scabbling is the final stage prior to the free release of a nuclear facility. In the context of Veurey and Annecy final cleanup and declassification

  16. AREVA 2010 annual results; AREVA resultats annuels 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Areva's 44-billion euro backlog at the end of 2010 gives the group excellent visibility, enabling it to confirm its outlook for 2012: 12 billion euros in revenue, double-digit operating margin and significantly positive free operating cash flow. Revenue rose by 575 million euros in 2010, or 6.7%, in comparison to 2009 and operating income excluding particular items improved by 201 million euros, nearly 2 points of revenue. In the past two years, Areva has raised 7.1 billion euros and secured its liquidity to ensure its development. In 2011, Areva is going to simplify the group's capital structure by listing ordinary shares of AREVA. At that time, the group may launch the employee share-holding plan, something it has ardently sought for several years as a way for its employees to share in AREVA's growth. The consolidated backlog stood at 44.204 billion euros at December 31, 2010, up 2.0% compared with that at December 31, 2009. The group's consolidated revenue came to 9.104 billion euros in 2010, up 6.7% on a reported basis and 5.1% like-for-like compared with 2009. Excluding particular items, operating income rose by 1.9 point, going from 3.9% in 2009 to 5.8% in 2010, giving operating income of 532 million euros (331 million euros in 2009). Net income attributable to equity owners of the parent came to 883 million euros in 2010, an increase of 331 million euros compared with 2009. Operating cash flow before capex was 923 million euros, an increase of 548 million euros compared with 2009, when it was 375 million euros, due to the visible improvement in EBITDA and working capital requirement. The change in gross capex (excluding acquisitions) from 1.780 billion euros in 2009 to 1.966 billion euros in 2010 is due to the ramp-up of construction programs, particularly in Enrichment. In 2010, almost 60% of the group's capital spending was on sites in France. The acquisitions made in Renewable Energies in 2010 in the amount of 210 million euros

  17. Annual report 2001. A (AREVA) for..; Rapport annuel 2001. A (AREVA) comme..

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This annual report 2001, on the group Areva, provides data and information on the Areva emerges, overview of operations, sustainable development policy, research and development programs, nuclear power activities (front-end, reactors and services back-end divisions), components (connectors division and STMicroelectronics, human resources, share data and the financial report. (A.L.B.)

  18. Reference document 2001. A (AREVA) for..; Document de reference 2001. A (AREVA) comme..

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This reference document 2001, on the group Areva, provides data and information on the Areva emerges, overview of operations, sustainable development policy, research and development programs, nuclear power activities (front-end, reactors and services back-end divisions), components (connectors division and STMicroelectronics, human resources, share data and financial information (financial report 2001, financial report first-half 2002). (A.L.B.)

  19. The IRSN Institute of radiation protection and nuclear safety Cadarache Center; L'IRSN Institut de Radioprotection et de Surete Nucleaire Centre de Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The research programs of the IRSN in the Cadarache Center concern the nuclear safety (reactor safety, nuclear fuels behavior during accidents, fires in nuclear installations), the protection and the control of radioactive materials, the human and the environment protection. The programs are presented and discussed. This presentation includes also the regional impact of the Institute at Cadarache (economical impact, relations with the universities and international meetings). (A.L.B.)

  20. Areva and sustainable development 2003 summary report; Areva et le developpement durable abrege 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This document is a summary of the 2003 report on the sustainable development of the world nuclear industry leader, Areva. The 2002 report helped establish the status of Areva entities sustainable development performance and identity areas for improvement. The 2003 report presents the continuous improvement process, including accomplishments and projects initiated as well as difficulties encountered and ground yet to be covered. Two new tools support this process. The Areva Way self assessment model allows each unit to assess its own performance against the sustainable development commitments and the Areva values charter lays down ethical principles of action and rules of conduct. Over the coming months, the Group will devote considerable effort to extending the sustainable development initiative to the activities resulting from the acquisition of Alstom Transmission and Distribution operations in early 2004. (A.L.B.)

  1. AREVA and sustainable development - 2003 report; Rapport developpement durable 2003 - AREVA

    Energy Technology Data Exchange (ETDEWEB)

    Lauvergeon, A

    2003-07-01

    The first report helped establish the status of Areva entities sustainable development performance and identify areas for improvement. This second report will report on the continuous improvement process, including accomplishments and projects initiated as well as difficulties encountered and ground yet to be covered. It includes, the Areva role in key sustainable development issues, the commitments and the governance, the risk management, the economic responsibility, the social responsibility and the environmental responsibility. (A.L.B.)

  2. AREVA net income: 649 million euros

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-03-15

    This document presents the financial statements for 2006 of Areva group: net income: 649 million euros; backlog up by 24.6% to 25.6 billion euros; steady growth of sales revenue: + 7.3%1 to 10.863 billion euros; operating income of 407 million euros: excellent divisional performance and constitution of a significant provision for the OL3 project in Finland; dividend proposed to Annual General Meeting of Shareholders: 8.46 euros per share.

  3. 1. half results 2003 - AREVA group; Resultats du 1. semestre 2003 - groupe AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-10-01

    This financial presentation of the Areva group, the world nuclear industry leader, results for the first half 2003 highlights the good level of activity, the negotiations with URENCO in final stages concerning the enrichment, the revision of estimates and negotiations underway concerning the dismantling and the operating income positive in Q2 2003 concerning the connectors division. (A.L.B.)

  4. Areva group. Result, first half 2004; Resultats du 1. semestre 2004. Groupe Areva

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-09-01

    Areva, a world nuclear industry leader, provides by this document information and key data on the performance and detailed financial data of the first half 2004. The transmission and distribution integration plan 2004-2006 is also detailed. (A.L.B.)

  5. AREVA sustainable development indicators guidelines; Guide methodologique des indicateurs developpement durable AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-12-01

    These guidelines set out the procedures used to measure and report the sustainable development and continuous progress data and indicators used within the Areva Group. It defines the scope of the guide, the list of indicators, the measurement and calculation procedures, the internal and external audits. (A.L.B.)

  6. AREVA Technical Days (ATD) session 1: Energy outlook and presentation of the Areva Group; AREVA Technical Days (ATD) session 1: enjeux energetiques et presentation du groupe AREVA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    These technical days organized by the Areva Group aims to explain the group activities in a technological and economic point of view, to provide an outlook of worldwide energy trends and challenges and to present each of their businesses in a synthetic manner. This first session deals with energy challenges and nuclear, public acceptance of nuclear power, mining activities, chemistry activities, enrichment activities, fuel assembly, reactors and services activities, nuclear measurements activities, reprocessing and recycling activities, logistics activities and connectors activities. (A.L.B.)

  7. Areva: clinical trials for a new treatment to fight cancer; Areva: essais cliniques pour un nouveau traitement contre le cancer

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2011-01-15

    Areva Med, the branch of Areva dedicated to nuclear medicine, has been agreed by the American Food and Drug Administration to begin the validation of a new treatment to fight cancer. This treatment is called alpha radio-immunotherapy and is based on the use of Pb{sup 212}. The validation phase aims at testing its efficiency on patients and will start in 2011 and will last 2 years. Areva has developed a process to extract Pb{sup 212} from thorium coming from ancient industrial activities. (A.C.)

  8. The Areva Group back-end division - challenges and prospects; Le pole aval dans le groupe Areva - enjeux et perspectives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-06-01

    This document presents the Areva Group back-end division challenges and prospects. Areva, a world nuclear industry leader, analyzes in this document, the high-profile mix of complementary activities of the nuclear energy industry, concerning the back-end division the full range of services for the end of the fuel cycle, the fuel cycle back-end markets, the economic and financial associated considerations. (A.L.B.)

  9. Areva - Press release from the Supervisory Board; Areva - Communique de presse du Conseil de Surveillance

    Energy Technology Data Exchange (ETDEWEB)

    Marie, Patricia; Briand, Pauline; Floquet-Daubigeon, Fleur; Michaut, Maxime; Scorbiac, Marie de; Repaire, Philippine du

    2012-02-14

    During its meeting held on December 12, 2011, devoted in particular to the examination of the 2011 closing estimates, the AREVA Executive Board indicated that it expected to book a provision of 1.46 billion euros (2.025 billion US dollars) in the company's accounts for fiscal year 2011 for impairment of assets for the reporting entity UraMin, a mining company acquired by AREVA in 2007, which, given the provision booked in 2010 (426 million euros), brings the value of these assets on the AREVA balance sheet down to 410 million euros. Given the size of these provisions, the Supervisory Board decided to make three of its members, meeting as an ad hoc committee, in charge of analyzing the terms of acquisition of this company, as well as the key decisions made in this reporting entity up to 2011 and, based on the outcome of these analyses, to recommend to it any appropriate measures in AREVA's interest. This committee reported on its work during the Supervisory Board meeting held on February 14, 2012. In light of this report, the Supervisory Board found that the fairness and reliability of the financial statements of previous years were not in question. Nevertheless, considering the malfunctions raised, the Board considers it appropriate to thoroughly review AREVA's governance in order to ensure that decisions concerning large acquisitions or investments be reviewed and validated in the future under conditions ensuring better legal and financial security and enabling a more transparent dialogue between management and the Supervisory Board. It thus asked the Executive Board to recommend, at the next General Meeting of Shareholders, that the by-laws of the company be modified to make the Supervisory Board's prior approval of investments, stake acquisitions and acquisitions mandatory above a threshold of 20 million euros. It also decided to set up a business ethics committee within the Supervisory Board responsible for ensuring that rules of conduct are

  10. Areva as of December 31, 2011; Areva au 31 decembre 2011

    Energy Technology Data Exchange (ETDEWEB)

    Marie, Patricia; Briand, Pauline; Michaut, Maxime; Scorbiac, Marie de; Repaire, Philippine du

    2012-01-26

    In 2011, AREVA's consolidated revenue came to 8.872 billion euros, down slightly (-2.6%) compared with 2010 (-1.2% like for like). The decrease in revenue in nuclear operations was partially offset by significant growth in the renewable energies business. Foreign exchange and changes in the scope of consolidation had respectively a negative impact of 113 million euros and 16 million euros over the period. Revenue totaled 2.922 billion euros in the fourth quarter of 2011, stable compared with the fourth quarter of 2010 (-0.5% on a reported basis and -0.5% like for like). Foreign exchange had a negligible impact during the period. Led by nuclear operations, the group's backlog was 45.6 billion euros at December 31, 2011, up 3.1% year on year and 6.7% in relation to September 30, 2011. Order cancellations since Fukushima were limited to 464 million euros as of December 31, 2011. In accordance with the requirements of IFRS 8, AREVA's business segment information is presented for each operating Business Group (BG), which is the level of information examined by the group's governance bodies. Subsequent to the establishment of a subsidiary combining all of the group's mining operations, data for the Mining Business Group are now reported separately from those of the Front End Business Group. Data used for comparisons with 2010 were restated to reflect this new organization. The business segment information therefore corresponds to AREVA's five operating Business Groups: Mining, Front End, Reactors and Services, Back End and Renewable Energies

  11. AREVA and sustainable development. 2002 report; AREVA et le developpement durable. Rapport 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The performance indicators in this report reflect the major sustainable development impacts and challenges that Areva is facing as a group due to the very nature of its operations. They chose the calendar year as reporting period, from January 1 to December 31. This report covers all of the group operations in France and abroad. This report presents an overview of the major financial, social and environmental challenges facing the group. This report is a companion document to the annual activity report. (A.L.B.)

  12. Areva half-year report june 30, 2006; Areva rapport semestriel 30 juin 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document is the half-year financial report of the Areva group for 2006. It presents: 1 - Highlights of the period; 2 - Key data: Summary data, Segment reporting, Backlog, Income statement, Review by business division, Cash flow, Balance sheet data; 3 - Outlook; 4 - Events subsequent to the half-year end; 5 - Consolidated financial statements: Statutory auditors' report on the interim consolidated financial statements for the period January 1, 2006 to June 30, 2006, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of changes in equity, Segment reporting, Notes to the consolidated financial statements.

  13. Areva half-year report June 30, 2008; Areva rapport semestriel 30 juin 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This document is the half-year financial report of the Areva group for 2008. It presents: 1 - the highlights of the period: key data (Summary data, Segment reporting, Backlog, Income statement, Review by division, Cash flow, Balance sheet data); Outlook; 2 - the events subsequent to half-year closing; 3 - the consolidated financial statements: Statutory Auditors' report on half-year 2008 information for the period January 1, 2008 to June 30, 2008, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of change in equity, Segment reporting, Notes to the consolidated financial statements for the period ending June 30, 2008.

  14. AREVA in 2007, growth and profitability

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This document is the 2007 activity report of the Areva group, the nuclear division of which is Number 1 worldwide in the front end of the nuclear cycle, in pressurized water reactors (in terms of installed capacity), and in the treatment and recycling of used nuclear fuel. The Transmission and Distribution division is Number 1 worldwide in market management software and grid management software, number 2 in high voltage products, and number 3 in medium voltage products. Content: Message from the Chairman of the Supervisory Board; Message from the Chief Executive Officer; Key data; 2007 highlights; Corporate governance; Organization of the group; Share information and shareholder relations; Solutions for CO{sub 2}-free power generation; Solutions for reliable electricity transmission and distribution; Governance; Continuous improvement; Financial performance; Innovation; Customer satisfaction; Commitment to employees; Environmental protection; Risk management and prevention; Dialogue and consensus building; Community involvement; Auditors' report; Reporting methodology; Data verified in 2007; Glossary; and 'to learn more' references.

  15. T and D on sale, Areva on punishment; T and D a la vente, Areva a la peine

    Energy Technology Data Exchange (ETDEWEB)

    Maincent, G

    2009-05-15

    Areva group, the world leader of the nuclear industry, is looking for 5 billion euros to finance its investments. However, the French government which owns 90% of the group, mainly through the CEA, is not willing to supply this financial help. Therefore, about 40% of Areva group's turnover could change hands soon. In fact, the French government has asked Areva to consider the selling of its daughter company T and D (Transmission and Distribution) which is one of the major poles of the group's activity. Thanks to T and D, Areva can propose a complete range of products, services and systems from the low- to the extra-high voltage, and can be present on other energy markets, from the conventional to the renewable power generation. Already weakened by the departure of Siemens, Areva, without T and D would lose its full power in front of competitors like GE-Hitachi, Toshiba-Westinghouse or Rosatom-Siemens. (J.S.)

  16. Proceedings of the Areva Technical Days. Session 5

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This document presents the proceedings of the Areva technical days, presented during the session 5 the 9 and 10 december 2004, at Istanbul. It deals with the operations of the transmission and distribution division. With manufacturing facilities in over 40 countries and a sales network in over 100, Areva offers customers technological solutions for nuclear power generation and electricity transmission and distribution (the Group also provides interconnect systems to the telecommunications, computer and automotive markets). It provides five topics: a general presentation of Areva, the strategic stakes for transmission and distribution by world-zone, economic and strategic stakes of business unit products, business unit systems and business unit automation. (A.L.B.)

  17. Results of a large scale neutron spectrometry and dosimetry comparison exercise at the Cadarache moderator assembly

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, D.J.; Naismith, O.F.; Taylor, G.C. [National Physical Lab., Teddington (United Kingdom); Chartier, J.-L.; Posny, F. [CEA Centre d`Etudes de Fontenay-aux-Roses, 92 (France). Inst. de Protection et de Surete Nucleaire; Klein, H. [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany)

    1997-09-01

    Eurados Working Group 7 recently organised a large-scale comparison of neutron spectrometry and dosimetry measurements at the IPSN/SDOS laboratory of the CEA Cadarache Research Centre in France. A large number of participants took part with a range of instruments including spectrometers, tissue-equivalent proportional counters, personal dosemeters, and survey instruments. The neutron field used for the exercise was a primarily low energy neutron spectrum similar to those which have been measured recently around nuclear facilities. This paper presents the results of the measurements and attempts to draw conclusions about the accuracy attainable with the various devices, their advantages and drawbacks, and potential problems. (author).

  18. Areva - First half 2008 sales revenue; Areva - Chiffre d'affaires du 1. semestre 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    As of June 30, 2008, AREVA's backlog stood at 38.1 billion euro, for 13.6% growth since June 30, 2007, with 9.9% growth in Nuclear and 40.7% growth in Transmission and Distribution. In Nuclear, the backlog came to 32.3 billion euro as of the end of June 2008. In the front end of the cycle, AREVA signed multi-year contracts in the first half of the year with Japanese and American utilities and with EDF, for a combined total of more than 1 billion euro. Of note in the back end of the cycle is the contract AREVA signed with the U.S. Department of Energy to build a MOX fuel fabrication facility. In Transmission and Distribution, the backlog came to 5.8 billion euro as of the end of period. A total of 3.2 billion euro in orders was booked in the first half, an increase of 20.0% year-on-year. The division won several important contracts, most notably a contract with Dubai Electricity (more than 130 million euro), a contract with National Grid and RTE for the renovation of the IFA 2000 grid interconnection between France and Great Britain (more than 60 million euro), and, in the industrial field, a contract with Rio Tinto Alcan (close to 65 million euro). The group cleared revenue of 6.2 billion euro in the first half of 2008, up 14.8% (+16.4% like-for-like) compared with the first half of 2007. Sales outside France were up 14.3% to 4.2 billion euro or 68.6% of total sales; the latter were stable compared with the first half of 2007. All businesses were up, with growth of 15.9% in Nuclear operations (+19.1% LFL1) - particularly in Reactors and Services (+31.3% LFL1) - and 13.0% growth in Transmission and Distribution operations (+12.0% LFL T 1). Foreign exchange had a negative impact of 155 million euro, primarily due to the change in the U.S. dollar in relation to the euro. Changes in the consolidated group had a positive impact of 97 million euro, mainly reflecting acquisitions in the Transmission and Distribution division and in Renewable Energies. Sales revenue

  19. Areva half-year report june 30, 2007; Areva rapport semestriel 30 juin 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    Information provided in this document concerns the AREVA group as a whole. It presents the highlights and Key data of the first half of 2007, the outlook, the events subsequent to half-year closing, and the Consolidated financial statements. Contents: 1 - Highlights of the period; 2 - Key data: Summary data, Segment reporting, Backlog, Income statement, Review by division, Cash flow, Balance sheet data; 3 - Outlook; 4 - Events subsequent to half-year closing; 5 - Consolidated financial statements: Statutory Auditors' report on half-year information for the period January 1, 2007 to June 30, 2007, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of change in equity, Segment reporting, Notes to the consolidated financial statements for the period ending June 30, 2007.

  20. AREVA Technical Days (ATD) session 4: operations of the front-end division of the nuclear fuel cycle; AREVA Technical Days (ATD) session 4: les activites du pole Amont

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    These technical days organized by the Areva Group aims to explain the group activities in a technological and economic point of view, to provide an outlook of worldwide energy trends and challenges and to present each of their businesses in a synthetic manner. This fourth session deals with the strategic and financial significance of the Areva mining operations, the Areva chemistry business, the Areva enrichment business and the Areva fuel business. (A.L.B.)

  1. Influence of high permeability disks in an axisymmetric model of the Cadarache dynamo experiment

    CERN Document Server

    Giesecke, A; Stefani, F; Gerbeth, G; Léorat, J; Herreman, W; Luddens, F; Guermond, J -L

    2011-01-01

    Numerical simulations of the kinematic induction equation are performed on a model configuration of the Cadarache von-K\\'arm\\'an-Sodium dynamo experiment. The effect of a localized axisymmetric distribution of relative permeability {\\mu} that represents soft iron material within the conducting fluid flow is investigated. The critical magnetic Reynolds number Rm^c for dynamo action of the first non-axisymmetric mode roughly scales like Rm^c({\\mu})-Rm^c({\\mu}->infinity) ~ {\\mu}^(-1/2) i.e. the threshold decreases as {\\mu} increases. This scaling law suggests a skin effect mechanism in the soft iron disks. More important with regard to the Cadarache dynamo experiment, we observe a purely toroidal axisymmetric mode localized in the high permeability disks which becomes dominant for large {\\mu}. In this limit, the toroidal mode is close to the onset of dynamo action with a (negative) growth-rate that is rather independent of the magnetic Reynolds number. We qualitatively explain this effect by paramagnetic pumping...

  2. Nuclear renaissance in the reactor training of Areva

    Energy Technology Data Exchange (ETDEWEB)

    De Braquilanges, Bertrand [Reactor Training Center/France Manager, La Tour Areva - 1, place Jean Millier - 92084 Paris - La Defense (France); Napior, Amy [Reactor Training Center/USA Manager, 1300 Old Graves Mill Road - Lynchburg VA, 2450 (United States); Schoenfelder, Christian [Reactor Training Center/Germany Manager, Kaiserleistrasse 29 - 63067 Offenbach (Germany)

    2010-07-01

    Because of the perspectives of new builds, a significant increase in the number of design, construction and management personnel working in AREVA, their clients and sub-contractors has been estimated for the next future. In order to cope with the challenge to integrate newly hired people quickly and effectively into the AREVA workforce, a project - 'Training Task Force (TTF)' - was launched in 2008. The objective was to develop introductory and advanced courses and related tools harmonized between AREVA Training Centers in France, Germany and USA. First, a Global Plants Introductory Session (GPIS) was developed for newly hired employees. GPIS is a two weeks training course introducing in a modular way AREVA and specifically the activities and the reactors technical basics. As an example, design and operation of a nuclear power plant is illustrated on EPRTM. Since January 2009, these GPIS are held regularly in France, Germany and the US with a mixing of employees from these 3 regions. Next, advanced courses for more experienced employees were developed: - Advanced EPR{sup TM}, giving a detailed presentation of the EPR{sup TM} reactor design; - Codes and Standards; - Technical Nuclear Safety. Finally, feasibility studies on a Training Material Management (TMM) system, able to manage the training documentation, and on a worldwide training administration tool, were performed. The TTF project was completed mid of 2009; it transferred their recurrent activities to a new AREVA training department. This unit now consists of the French, German and US Reactors Training Centers. In particular, all courses developed by the TTF are now implemented worldwide with an opening to external trainees. The current worldwide course catalogue includes training courses for operation and maintenance personnel as well as for managers, engineers and non technical personnel of nuclear operators, suppliers, safety authorities and expert organizations. Training delivery is supported

  3. Areva - first half 2007 financial results; Areva - resultats du 1. semestre 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This document presents the financial statements of Areva group for the first half of 2007 as submitted by the Executive Board: Sales revenue: euro 5.373 billion, up by 6.7%; Operating income: euro 207 million, i.e. 3.9% operating margin, up 1.6 point compared with H1 2006; Consolidated net income: euro 295 million, i.e. euro 8.31 per share in H1 2007 against euro 6.92 per share in H1 2006, a 20% increase. All Group performance indicators were up the first half of 2007. Growth was robust and profitability strengthened significantly in terms of both operating income and net income. Consolidated sales revenue rose 6.7% for the first half of 2007 alone, after growth of more than 7% in 2006. This positive trend will continue: the backlog grew by 31% in the first half to more than euro 33 billion, compared with euro 26 billion six months ago and euro 21 billion at year-end 2005. Business is up sharply in the Transmission and Distribution division, which had operating margin of 8.7% in the first half of the year.

  4. AREVA - first half 2005 sales figures; AREVA - chiffre d'affaires du 1. semestre 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    First half 2005 sales for the AREVA group were up 1.1% to 5,396 million euros and 2.6% like-for-like, compared with 5,339 million euros for the same period in 2004.The change in foreign exchange rates had a negative impact of nearly (34) million euros between these two periods, which was much less than between the first half of 2003 and the same period in 2004. Sales are up 1.1% compared with the first half of 2004 (up 2.6% like-for-like); the euros (17.3) M impact of IFRS adoption is limited to the Front End division; Energy is up: Nuclear Power: up 4.4% (up 5.5% like-for-like), driven by the Front End and Reactors and Services divisions; T and D: down 3.9% (-2.1% like-for-like) due to the one time peak observed in early 2004; Connectors sales are stable (+0.3% like-for-like): Automotive performed well, while the communication market continued to be a difficult one.

  5. Large valve test facilities of AREVA NP GmbH

    Energy Technology Data Exchange (ETDEWEB)

    Beisiegel, A.; Wagner, T.; Stecher, W.

    2011-07-01

    As market leader in the field of nuclear power plant technology, AREVA runs an internationally-unique test and qualification infrastructure for power plant components. The associated Thermal-Hydraulic Platform with different test facilities in Karlstein and Erlangen has been recognized as a test body according to ISO 17025. The DAkkS the German Society for Accreditation has now also certified the Thermal-hydraulic Platorm as an independent inspection body Type C according to ISO 17020.

  6. Status of safety at Areva group facilities. 2007 annual report; Areva, etat de surete des installations nucleaires. Rapport annuel 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report describes the status of nuclear safety and radiation protection in the facilities of the AREVA group and gives information on radiation protection in the service operations, as observed through the inspection programs and analyses carried out by the General Inspectorate in 2007. Having been submitted to the group's Supervisory Board, this report is sent to the bodies representing the personnel. Content: 1 - A look back at 2007 by the AREVA General Inspector: Visible progress in 2007, Implementation of the Nuclear Safety Charter, Notable events; 2 - Status of nuclear safety and radiation protection in the nuclear facilities and service operations: Personnel radiation protection, Event tracking, Service operations, Criticality control, Radioactive waste and effluent management; 3 - Performance improvement actions; 4 - Description of the General Inspectorate; 5 - Glossary.

  7. Areva. 2007 figures economic, social, societal and environmental data; Areva. Chiffres 2007 donnees economiques, sociales, societales et environnementales

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This document presents the 2007 economic, social, societal and environmental data of the Areva Group. Content: 1 - Improvement initiative: Continuous improvement, Innovation; 2 - Financial performance: 2007 results; 3 - Commitment to employees: Stakeholder relations, Health and safety, Radiation protection, Radiological impacts, Technological risks, Workforce, Workforce and training; 4 - Environment: Water, Energy, Gaseous releases, Liquid releases, Conventional waste, Radioactive waste; 5 - Reporting and performance indicators: Reporting methodology, Auditors' report, Social indicators, Environmental indicators.

  8. Experience of Areva in fuel services for PWR and BWR; Experiencia de Areva en servicios de combustible para PWR y BWR

    Energy Technology Data Exchange (ETDEWEB)

    Morales, I.

    2015-07-01

    AREVA being an integrated supplier of fuel assemblies has included in its strategy to develop services and solutions to customers who desire to improve the performance and safety of their fuel. These services go beyond the simple 'after sale' services that can be expected from a fuel supplier: The portfolio of AREVA includes a wide variety of services, from scientific calculations to fuel handling services in a nuclear power plant. AREVA is committed to collaborate and to propose best-in-class solutions that really make the difference for the customer, based on 40 years of Fuel design and manufacturing experience. (Author)

  9. KROTOS FCI experimental programme at CEA Cadarache: new features and status

    Energy Technology Data Exchange (ETDEWEB)

    Bonnet, J.M.; Bullado, Y.; Journeau, C.; Fouquart, P.; Piluso, P.; Sergeant, C.; Magallon, D. [CEA-Cadarache, DTN/STRI/LMA, Bat 708, BP1, 13108 Saint Paul lez Durance cedex (France)

    2005-07-01

    Full text of publication follows: KROTOS facility has been operated by the European Commission at JRC-Ispra for many years until 1999 as part of the FARO/KROTOS programme. The programme had to be stopped at JRC due to new EC priorities, and an agreement was concluded with CEA to transfer the KROTOS facility and know-how to Cadarache to continue investigating the pending FCI issues. By this agreement, CEA became owner of the facility. The main objective of the KROTOS programme at CEA Cadarache is understanding the role of melt properties in steam explosion propagation and energetics and, in particular, steam explosion behaviour of prototypical corium melts. Possible influence of physicochemical processes on explosiveness will also be explored. Actually, analysis of alumina debris produced at Ispra have shown that formation of metastable phases and chemical reaction with water at high temperature may play a significant role in enhancing heat transfer to water in the explosion phase. In order to reach the objective, steam explosion experiments are performed in well characterised conditions for a large spectrum of conditions and melt compositions of interest for both in- and ex-vessel situations. A trigger is applied as a rule. Advanced technology and instrumentation is used to reduce uncertainties on initial conditions and characterise the various phases of an explosion, with emphasis on high energy X-ray cinematography to qualify pre-mixing. This advanced instrumentation will enable the measurement of detailed variables to consolidate the qualification of the FCI codes. The use of high energy X-rays made it necessary to construct a new building to house the facility and its components. The facility should newly become operative early 2005. Main improvements with respect to Ispra concern melt delivery, hydrogen measurement and X-ray imaging. Preliminary studies have demonstrated that identification of the pre-mixture-water interface and coherent melt jet core, and

  10. Status of safety at Areva group facilities. 2006 annual report; Etat de surete des installations nucleaires. Rapport annuel 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This report presents a snapshot of nuclear safety and radiation protection conditions in the AREVA group's nuclear installations in France and abroad, as well as of radiation protection aspects in service activities, as identified over the course of the annual inspections and analyses program carried out by the General Inspectorate in 2006. This report is presented to the AREVA Supervisory Board, communicated to the labor representation bodies concerned, and made public. In light of the inspections, appraisals and coordination missions it has performed, the General Inspectorate considers that the nuclear safety level of the AREVA group's nuclear installations is satisfactory. It particularly noted positive changes on numerous sites and efforts in the field of continuous improvement that have helped to strengthen nuclear safety. This has been possible through the full involvement of management teams, an improvement effort initiated by upper management, actions to increase personnel awareness of nuclear safety culture, and supervisors' heightened presence around operators. However, the occurrence of certain events in facilities has led us to question the nuclear safety repercussions that the changes to activities or organization on some sites have had. In these times of change, drifts in nuclear safety culture have been identified. The General Inspectorate considers that a preliminary analysis of the human and organizational factors of these changes, sized to match the impact the change has on nuclear safety, should be made to ensure that a guaranteed level of nuclear safety is maintained (allowance for changes to references, availability of the necessary skills, resources of the operating and support structures, etc.). Preparations should also be made to monitor the changes and spot any telltale signs of drift in the application phase. Managers should be extra vigilant and the occurrence of any drift should be systematically dealt with ahead of

  11. Web application for the control and management of radioprotection equipment in the Cadarache centre; Application WEB pour le controle et la gestion des appareils de radioprotection sur le centre de Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2010-07-01

    The author describes a web 2-type application which has been developed for the periodic calibration controls of radioprotection equipment in Cadarache. This application aims at offering an easy and immediate and even remote access to information, at selecting information with respect to uses (radioprotection department, administrator, and so on), at securing and safeguarding homogeneous data, at editing control statistics. The different functionalities are briefly presented with their displayed interface

  12. 78 FR 9431 - Shaw AREVA MOX Services, LLC (Mixed Oxide Fuel Fabrication Facility); Order Approving Indirect...

    Science.gov (United States)

    2013-02-08

    ... COMMISSION [NRC-2011-0081; Docket No. 70-3098; Construction Authorization No. CAMOX-001] Shaw AREVA MOX... Construction Authorization I Shaw AREVA MOX Services, LLC (MOX Services) holds Construction ] Authorization (CA) CAMOX-001 for construction of a Mixed Oxide (MOX) Fuel Fabrication Facility (MFFF) at the...

  13. 76 FR 22735 - Shaw AREVA MOX Services, Mixed Oxide Fuel Fabrication Facility; License Amendment Request, Notice...

    Science.gov (United States)

    2011-04-22

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Shaw AREVA MOX Services, Mixed Oxide Fuel Fabrication Facility; License Amendment Request, Notice.... Introduction The NRC has received, by letter dated February 8, 2011, an amendment request from Shaw AREVA...

  14. Вклад в атомную энергетику через Areva / Тармо Танилас

    Index Scriptorium Estoniae

    Танилас, Тармо

    2009-01-01

    Suurim tuumaenergia infrastruktuuride tootja, Prantsuse energeetikafirma Areva, sobib pikaajalisi invetseerimistrende otsivale investorile. Tabel: Areva turuosad tuumaenergia tootmisahelas. Graafik: Areva aktsia hind

  15. Rapport d'étude : La perception des risques majeurs par les riverains du CEA de Cadarache

    OpenAIRE

    Lopez, Alexia; Régner, Isabelle; Schleyer-Lindenmann, Alexandra

    2015-01-01

    Ce rapport d'étude vient répondre aux interrogations de son commanditaire, la CLI (Commission Local d'Information) du CEA (Commissariat à l'énergie Atomique) de Cadarache. Il s'organise en trois partie : une première partie établit un état des lieux des connaissances des risques majeurs par les habitants. Les risques majeurs officiellement recensés sont : le risque feu de forêt, le risque inondation, le risque sismique, le risque de mouvement de terrain, le risque de rupture de barrage, et le...

  16. The nuclear data, A key component for reactor studies, Overview of AREVA NP needs and applications

    Directory of Open Access Journals (Sweden)

    Ravaux Simon

    2016-01-01

    Full Text Available The quality of the nuclear data is essential for AREVA NP. Indeed, many AREVA NP activities such as reactor design, safety studies or reactor instrumentation use them as input data. So, the nuclear data can be considered as a key element for AREVA NP. REVA NP’s contribution in the improvement of the nuclear data consists in a joint effort with the CEA. It means a financing and a sharing of information which can give an orientation to the future research axis. The aim of this article is to present the industrial point of view from AREVA NP on the research on nuclear data. Several examples of collaborations with the CEA which have resulted in an improvement of the nuclear data are presented.

  17. Areva subcontracts in Japan the noble part of the Finnish EPR; Areva sous-traite au Japon la partie noble de l'EPR finlandais

    Energy Technology Data Exchange (ETDEWEB)

    Jemain, A

    2004-02-01

    Areva, the French energy group, will subcontract the manufacturing of the reactor vessel and cover of the European Pressurized Reactor (EPR) which will be built in Finland. These components will be manufactured in Japan by Mitsubishi and not by Areva's Chalon/Saint-Marcel factory. The reason is the overburden of work and the lack of room and of machining equipment in the French factory. Also, the turbine and alternator are not built by Alstom, but by Siemens (Germany). (J.S.)

  18. Web software for the control and management of radiation protection devices in the Cadarache site; Application WEB pour le controle et la gestion des appareils de radioprotection sur le centre de Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    Beltritti, F. [CEA Cadarache 13108 St Paul lez Durance Cedex (France)

    2010-07-01

    This series of slides presents how to use a new software dedicated to the management of the periodical controls that have to be performed on the equipment involved in radiation protection. This software is ready to be dispatched on the CEA site of Cadarache. This software gives information on: the device to be controlled, the controls that have to be performed, the procedures to follow to make the test, the equipment necessary for the test particularly the need for radioactive sources, the maintenance of the device, the previous measurements and in the end the device's conformity. An evaluation of the conformity of all the devices present in a building or an area or of a particular type can be easily obtained. (A.C.)

  19. Areva 2007 results: accelerated growth and significantly improved profitability; Areva resultats 2007: acceleration de la croissance et hausse significative de la profitabilite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-02-15

    The AREVA group recorded accelerated growth and increased profitability in 2007, meeting both of its objectives for the year. The group made strategic inroads in fast growing markets. AREVA's integrated model met with record success in China, where GGNPC acquired two EPR nuclear islands in a combined order including both the reactors and the fuel, and the creation of a joint venture in engineering. Its T and D division was awarded the largest contract of its history in Qatar, making it the leader in a region where T and D was not even present a few years ago. For more than three years, AREVA has built up its capacity to meet surging demand in the nuclear power and T and D markets through an active policy of research and development and by capitalizing on the diversity and strength of its partnerships. Areva hired 8,600 people in 2006 and 11,500 people in 2007; this represents an investment in recruitment, training and integration of approximately euro 200 million per year. For 2008, the group foresees a further increase in its backlog, sales revenue and operating income. The Areva Group financial statements for 2007 are summarized below: - Backlog: euro 39.8 billion, up 55%; - Sales revenue: euro 11.9 billion, up 9.8% (up 10.4% like-for-like); - Operating income: euro 751 million, i.e. 6.3% operating margin, up 2.6 points compared with 2006; - Net income attributable to equity holders of the parent: euro 743 million (euro 20.95 per share), up from euro 649 million in 2006 (euro 18.31 per share); - Net debt: euro 1.954 billion, linked to the acquisition of UraMin; - Dividend: euro 6.77, to be proposed to the Annual General Meeting of Shareholders convening on April 17, 2008.

  20. The AREVA's waste management strategy; La strategie de gestion des dechets radioactifs d'AREVA

    Energy Technology Data Exchange (ETDEWEB)

    Poncet, Ph. [AREVA NP, Tour AREVA, Direction surete, securite, sante environnement - D3SE, 92 - Paris La Defense (France)

    2011-02-15

    In accordance with its policy of sustainable development and continuous progress, AREVA is permanently seeking to reduce the impact of the management of its waste, of whatever type, and its radioactive waste in particular. This goal is taken into consideration very early in industrial projects and concerns all the phases in the life of the installations and all the activities of the Group. The resulting actions aim to guarantee that an exhaustive inventory is made of the radioactive materials and waste, to optimise how they are characterised, to ensure their traceability and to determine the best management methods. Past and future progress relies primarily on the effectiveness of zoning (in particular the concept of radiological cleanness), how work is organized, the account taken of operating experience feedback, the search for recycling solutions or appropriate removal routes, optimisation of waste storage and, whenever possible, online processing, plus of course the professionalism of all those involved. A participatory approach by the Group will enable the focus areas and required actions to be defined: networks and multidisciplinary working groups, whenever possible in association with other stake-holders or partners from the nuclear industry. (author)

  1. Press kit. Cooperation between Areva and South Africa in the nuclear energy field

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document presents the nuclear industry business developed by Areva in South Africa. The first part offers general information on the country (political context, economy which fuels African growth, social situation and South Africa in search of sustainable development). An other part deals with the electricity supply (predominance of coal and the issue of global warming, electricity for everyone. The last parts detail the nuclear energy development (the new PBMR reactor project, the exploitation of all nuclear technology) and how Areva consolidates its presence in South Africa. (A.L.B.)

  2. Monitoring of the radiological environmental impact of the AREVA site of Tricastin; Suivi de l'impact radiologique environnemental des activites du site AREVA du Tricastin

    Energy Technology Data Exchange (ETDEWEB)

    Mercat, C.; Brun, F.; Florens, P.; Petit, J. [AREVA NC Pierrelatte, Direction surete environnement du site du Tricastin, 26 (France); Garnier, F. [EURODIF Production, Direction qualite securite surete environnement, 26 (France); Devin, P. [AREVA NC Pierrelatte, Direction surete, sante, securite, environnement, 26 (France)

    2010-06-15

    Set up at the beginning of the site's operations, in 1962, the monitoring of the radiological environmental impact of the AREVA site of Tricastin has evolved over time to meet more specifically the multiple objectives of environmental monitoring: to prove the respect of the commitments required by the authorities, to be able to detect a dysfunction in the observed levels, to enable the assessment of impacts of industrial activities, to ensure the balance between environmental quality and the use made by the local population and to inform the public of the radiological state of the environment. Thousands of data were acquired on the radioactivity of all environmental compartments as well as on the functioning of local ecosystems. Today, the Network of Environmental Monitoring of AREVA Tricastin goes beyond the requirements of routine monitoring to provide innovative solutions for monitoring the radioactivity (especially for uranium) in the environment. (author)

  3. Areva. Nine-month 2007 sales revenue and data; Areva. Informations et chiffre d'affaires relatifs au neuf premiers mois de l'exercice 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-10-15

    The main information concerning the nine-month 2007 financial data of the Areva group is a steady growth of 9-month sales revenue, at euro 8.066 billion (+6.8% like-for-like), including euro 2.692 billion in the 3. quarter, i.e. +7.6% like-for-like. The group confirms its strong sales revenue growth objective for 2007.

  4. 75 FR 62895 - Notice of Availability of Safety Evaluation Report; AREVA Enrichment Services LLC, Eagle Rock...

    Science.gov (United States)

    2010-10-13

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Notice of Availability of Safety Evaluation Report; AREVA Enrichment Services LLC, Eagle Rock... special nuclear material. This proposed facility is known as the Eagle Rock Enrichment Facility (EREF)...

  5. Areva 2009 responsible growth report: more energy, less CO{sub 2}; Areva rapport de croissance responsable 2009: plus d'energie moins de CO{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    This document is the 2009 annual responsible growth report of AREVA which presents itself as having consolidated its leadership position in its original business of nuclear power while expanding considerably in renewable energies (wind, solar, bio-energies and hydrogen/storage) to become a leading provider of solutions for carbon-free power generation. The main chapters of the report are: the group and its strategy, Areva's nuclear power solutions (is nuclear a sustainable energy source?, supply, technological excellence, safety, recycling and waste, acceptability, non-proliferation), Areva's renewable energy solutions (how much of the energy mix should be renewable?, rising demand, competitiveness and efficiency, responsible development), Areva's human resources (gender balance, health and safety, diversity and opportunity, hiring and training). Data and balanced scorecard for sustainable development are also given

  6. Areva new fuel designs; increased reliability, operating margins and operating efficiency; Nuevos disenos de combustible Areva: aumento de fiabilidad, margenes operativos y eficiencia del funcionamiento

    Energy Technology Data Exchange (ETDEWEB)

    Mollard, P.; Vollmer, N.; Curca-Tivig, F.; Cole, S.; Louf, H. P.

    2015-07-01

    AREVA is continuously working on the improvement of the fuel design to address immediate and future needs of the utilities. This improvement process regularly leads to incremental changes but also to breakthrough changes addressing the next needs of the market. Since a few years now, the improvements of the fuel design and licensing benefit from the improvement and upgrade in codes and methods and computational capabilities. Changes in design are sustained by these more powerful and phenomenological tools which secure and fasten the fuel design optimization and its implementation. (Author)

  7. EPR construction at China's Taishan progressing well, Says Areva

    Energy Technology Data Exchange (ETDEWEB)

    Mitev, Lubomir [NucNet, Brussels (Belgium)

    2014-04-15

    Construction of two EPR units at the Taishan nuclear site in China's southern Guangdong province is 'progressing well', with 95 percent of procurement orders placed and 82 percent of engineering work completed, Areva has said. All primary heavy components have been delivered and installed for the first unit, Taishan-1, and the delivery of heavy components for Taishan-2 is under way. Areva is nuclear island supplier for the two 1,600 MW units. Its customer is the China Guangdong Nuclear Power Holding Corporation (CGNPC), represented by the Taishan Nuclear Power Company (TNPJVC). TNPJVC is a joint venture between CGNPC and France's EDF. Negotiations for Taishan-3 and -4 are expected to restart soon following the suspension of new-build authorisations after the Fukushima-Daiichi accident in March 2011. China plans to have 58,000 MW of installed nuclear capacity. (orig.)

  8. First half 2006 financial results; Resultats du 1er semestre 2006 Groupe Areva

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-09-15

    Areva provides technological solutions for highly reliable nuclear power generation and electricity transmission and distribution. The group is the world leader in nuclear power and the only company to cover all industrial activities in this field. This Press release presents the first half 2006 financial results: the overall performance and the performance by division (front end, reactors and services, back end, transmission and distribution). (A.L.B.)

  9. Waste Estimates for a Future Recycling Plant in the US Based Upon AREVA Operating Experience - 13206

    Energy Technology Data Exchange (ETDEWEB)

    Foare, Genevieve; Meze, Florian [AREVA E and P, SGN - 1, rue des Herons, 78182 Montigny-le-Bretonneux (France); Bader, Sven; McGee, Don; Murray, Paul [AREVA Federal Services LLC, 7207 IBM Drive, Mail Code CLT- 1D, Charlotte NC 28262 (United States); Prud' homme, Pascal [AREVA NC SA - 1, place Jean Millier, 92084 Paris La Defense CEDEX (France)

    2013-07-01

    Estimates of process and secondary wastes produced by a recycling plant built in the U.S., which is composed of a used nuclear fuel (UNF) reprocessing facility and a mixed oxide (MOX) fuel fabrication facility, are performed as part of a U.S. Department of Energy (DOE) sponsored study [1]. In this study, a set of common inputs, assumptions, and constraints were identified to allow for comparison of these wastes between different industrial teams. AREVA produced a model of a reprocessing facility, an associated fuel fabrication facility, and waste treatment facilities to develop the results for this study. These facilities were divided into a number of discrete functional areas for which inlet and outlet flow streams were clearly identified to allow for an accurate determination of the radionuclide balance throughout the facility and the waste streams. AREVA relied primarily on its decades of experience and feedback from its La Hague (reprocessing) and MELOX (MOX fuel fabrication) commercial operating facilities in France to support this assessment. However, to perform these estimates for a U.S. facility with different regulatory requirements and to take advantage of some technological advancements, such as in the potential treatment of off-gases, some deviations from this experience were necessary. A summary of AREVA's approach and results for the recycling of 800 metric tonnes of initial heavy metal (MTIHM) of LWR UNF per year into MOX fuel under the assumptions and constraints identified for this DOE study are presented. (authors)

  10. Our energies have a future. A future without CO{sub 2}. Areva in 2005; Nos energies ont de l'avenir. Un avenir sans CO{sub 2}. Areva en 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document is the sustainable development and 2005 annual report altogether of Areva group. It presents first the challenges of energy for economical development, the climate change threat and the sustainability of nuclear power in particular with respect to radioactive wastes management and power blackouts. Then follows a presentation of Areva's 10 commitments for sustainable development (governance and continuous improvement, financial performance, innovation, customer satisfaction, commitment to employees, risk management and prevention, environmental protection, dialogue and consensus building, community involvement). The annual report presents: the 2005 highlights, Areva around the world, key data, corporate governance, organisation of the group, share information and shareholder relations, business review (front end division, reactors and services division, back end division, transmission and distribution division), financial report and glossary. (J.S.)

  11. Benchmark Cea - AREVA NP - EDF of the corrosion facilities for VHTR material testing

    Energy Technology Data Exchange (ETDEWEB)

    Cabet, C. [CEA Saclay, Dept. de Physico-Chimie (DEN/DPC/SCCME), 91 - Gif sur Yvette (France); Terlain, A.; Seran, J.L.; Girardin, G.; Kaczorowski, D. [CEA Saclay, Dept. des Materiaux pour le Nucleaire (DEN/DMN), 91 - Gif-sur-Yvette (France); Blat, M. [AREVA NP - NTC-F, Technical Center Le Creusot, 71 - Le Creusot (France); Dubiez Le Goff, S. [Electricite de France (EDF R and D), Chemistry and Corrosion group, MMC Dept., 77 - Moret sur Loing (France)

    2007-07-01

    Within the framework of the ANTARES program, the French Cea, AREVA-NP and EDF have launched a joint program on metallic materials for application in innovative Very High Temperature Reactors (VHTR). Since corrosion is highly sensitive to environmental conditions, material studies require dedicated facilities that permit a strict control of the metallic specimen environment throughout the entire exposure. Cea, AREVA-NP and EDF have developed experimental setups respectively under the names CORALLINE and CORINTH, the Chemistry Loop and ESTEREL; these high temperature helium flow systems are fitted with hygrometers and gas analyzers. A benchmarking procedure was defined to inter-validate these lab devices. It is composed of two tests. The joint protocol has set the operating parameters. Process atmospheres are made of helium with 200 {mu}bar H{sub 2}, 20 {mu}bar CH{sub 4}; the CO content reaches 50 {mu}bar for test 1 while it is reduced to 5 {mu}bar CO in test 2. The residual water vapor concentration shall be lower than 3{mu}bar. Corrosion is assessed by mass change associated to observations and analyses of the corroded coupons considering the surface scales (nature, morphology and thickness), the internal oxidation (nature, distribution and depth) and the possible carburization/decarburization (type and depth). For benchmark test 1, Cea, AREVA-NP and EDF produced similar results in terms of operation of the tests as well as about the Inconel 617 corrosion criteria. On the other hand, benchmark test 2 showed a difference in the residual water vapor level between CORALLINE and the Chemistry Loop that was shown to strongly influence the specimen behavior.

  12. AREVA solutions to licensing challenges in PWR and BWR reload and safety analysis

    Energy Technology Data Exchange (ETDEWEB)

    Curca-Tivig, Florin [AREVA GmbH, Erlangen (Germany)

    2016-05-15

    Regulatory requirements for reload and safety analyses are evolving: new safety criteria, request for enlarged qualification databases, statistical applications, uncertainty propagation.. In order to address these challenges and access more predictable licensing processes, AVERA is implementing consistent code and methodology suites for PWR and BWR core design and safety analysis, based on first principles modeling and extremely broad verification and validation data base. Thanks to the high computational power increase in the last decades methods' development and application now include new capabilities. An overview of the main AREVA codes and methods developments is given covering PWR and BWR applications in different licensing environments.

  13. Joining the Nuclear Renaissance with the Engineering Business Unit of AREVA

    Energy Technology Data Exchange (ETDEWEB)

    Hubert, Nathalie; Menguy, Stephane [SGN, AREVA Group, 1 rue des Herons, 78182 Saint-Quentin en Yvelines Cedex (France); Valery, Jean-Francois [AREVA NC, AREVA Group, Tour AREVA, 1 place de la Coupole, 92084 Paris La Defense Cedex (France)

    2008-07-01

    The reality of the nuclear renaissance is no longer a question. All over the world, new nuclear plants are going to be deployed; the whole fuel cycle has to be adjusted to fulfil their needs, the front-end to produce the fuel and the back-end to properly manage radioactive waste. AREVA fuel cycle engineering teams have been involved in the design of a variety of industrial plants covering the entire fuel cycle for 50 years. The consistency of the French nuclear policy has been a major factor to acquire and renew the competencies and workforce of AREVA Engineering Business Unit. Our partnership with our customers, French ones but also Japanese, Americans and from other countries, has led us to develop a comprehensive approach of the services that we can deliver, in order to give them the best answer. SGN teams have been involved in the R and D phases in order to take into account the industrialisation aspects as early as possible, and our work does not end with the delivery of the plants; it includes assistance to the operators to optimise and keep their facilities in line with the changing rules and constraints, which ensures the integration of a wide operational experience feedback and the ability to design flexible facilities. This paper will present through our experience how this global approach has been developed and continuously improved and how we are preparing our teams to be ready to answer to the coming needs. (authors)

  14. Forward alliance. AREVA's initiative for NPP's LTO projects

    Energy Technology Data Exchange (ETDEWEB)

    Bergholz, Steffen; Heinz, Benedikt; Rudolph, Juergen [AREVA GmbH, Erlangen (Germany); Quist, Perry [EPZ - Elektriciteits-Productiemaatschappij Zuid-Nederland N.V., Borssele (Netherlands)

    2014-08-15

    Nowadays, the abbreviation LTO (Long Term Operation) is well known in the NPP's world. No other kind of projects can ensure the actual economic and environmental questions of the world of energy production with this high efficiency. Two-thirds of the actual international NPP fleet in operation has reached an age of more than 25 years. The former NPP's design life of normally 40 years has changed to 60 years for new plants. Furthermore, the existing fleet is nominally prepared for an operational period of more the 40 years. AREVA had launched the Forward Alliance initiative which offers different activities to ensure a support of customer's LTO projects. This article will give an overview on the Forward Alliance initiative followed by a technical example how the AREVA Fatigue Concept (AFC) can fulfill the fatigue monitoring topic within potential LTO projects. The successfully realized LTO project for NPP Borssele (Netherlands) shows as a customer example how the Forward Alliance blocks can work.

  15. AREVA revenue and data for the first nine months of 2008; AREVA informations et chiffre d'affaires relatifs aux neuf premiers mois de l'exercice 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This public information sheet presents financing data of the group AREVA for the first nine months of 2008. It shows a high increase of the revenue (12,9%). The data are detailed for each activity sector, front end, reactors and services, back end, transmission and distribution. Consolidated revenue for the years 2007 are also provided. (A.L.B.)

  16. Phase 1A Final Report for the AREVA Team Enhanced Accident Tolerant Fuels Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Morrell, Mike E. [AREVA Federal Services LLC, Charlotte, NC (United States)

    2015-03-19

    In response to the Department of Energy (DOE) funded initiative to develop and deploy lead fuel assemblies (LFAs) of Enhanced Accident Tolerant Fuel (EATF) into a US reactor within 10 years, AREVA put together a team to develop promising technologies for improved fuel performance during off normal operations. This team consisted of the University of Florida (UF) and the University of Wisconsin (UW), Savannah River National Laboratory (SRNL), Duke Energy and Tennessee Valley Authority (TVA). This team brought broad experience and expertise to bear on EATF development. AREVA has been designing; manufacturing and testing nuclear fuel for over 50 years and is one of the 3 large international companies supplying fuel to the nuclear industry. The university and National Laboratory team members brought expertise in nuclear fuel concepts and materials development. Duke and TVA brought practical utility operating experience. This report documents the results from the initial “discovery phase” where the team explored options for EATF concepts that provide enhanced accident tolerance for both Design Basis (DB) and Beyond Design Basis Events (BDB). The main driver for the concepts under development were that they could be implemented in a 10 year time frame and be economically viable and acceptable to the nuclear fuel marketplace. The economics of fuel design make this DOE funded project very important to the nuclear industry. Even incremental changes to an existing fuel design can cost in the range of $100M to implement through to LFAs. If this money is invested evenly over 10 years then it can take the fuel vendor several decades after the start of the project to recover their initial investment and reach a breakeven point on the initial investment. Step or radical changes to a fuel assembly design can cost upwards of $500M and will take even longer for the fuel vendor to recover their investment. With the projected lifetimes of the current generation of nuclear power

  17. Teach NC Basics Step by Step.

    Science.gov (United States)

    Schroeder, Roger

    1978-01-01

    Rapid expansion of numerical control (NC) machining in industry has created the need for inclusion of NC basic concepts in the industrial education curriculum. The author describes an NC unit in an industrial technology class and the program sheet and NC worksheet that he developed for machining a product. (MF)

  18. 77 FR 70193 - Shaw Areva MOX Services (Mixed Oxide Fuel Fabrication Facility); Notice of Atomic Safety and...

    Science.gov (United States)

    2012-11-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Shaw Areva MOX Services (Mixed Oxide Fuel Fabrication Facility); Notice of Atomic Safety and Licensing Board Reconstitution Pursuant to 10 CFR 2.313(c) and 2.321(b), the Atomic Safety and...

  19. Areva revenue and data for the first quarter of 2008; Areva informations et chiffre d'affaires relatifs au 1. trimestre de l'exercice 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    First quarter 2008 revenue was up 12.1% year-on-year, to 2.769 billion euros. Like-for-like (at constant exchange rates and consolidation scope), growth came to 14.5%. Foreign exchange had a negative impact of 2.5%, or -69 million euros, mainly due to currency translation tied to the US dollar drop compared with the euro. The consolidation scope had a positive impact of +0.7% or 18 million euros, chiefly as a result of the consolidation of VEI Distribution (specializing in medium voltage distribution) and Passoni and Villa (world leader in the manufacture of high voltage bushings) in the Transmission and Distribution division. The main growth engines for first quarter revenue were the Reactors and Services division and the Back End division, with growth of 29.7% (+36.8% LFL1) and 13.8% (+14.1% LFL1) respectively. Outside France, revenue rose to 1.857 billion euros, compared with 1.753 billion euros in the first quarter of 2007. This represents 67% of total revenue. As a reminder, the group points out that: - revenue can vary significantly from one quarter to the next in the nuclear businesses, and quarterly operations should therefore not be taken as a reliable basis for annual projections; - the foreign exchange impact mentioned in this release comes from the translation of subsidiary accounts into the group's unit of account, and primarily reflects the US dollar in relation to the euro. AREVA also points out that its foreign exchange hedging policy for commercial operations aims to shield profitability from fluctuations in exchange rates in relation to the euro.

  20. Concept and operational experience of the Areva DMT process for preventive maintenance of steam generators; Concepto y experiencia operacional del proceso DMT de Areva para el mantenimiento preventivo de generadores de vapor

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, S.; Gaspar, J. D.; Potier, P.; Jones, D.

    2015-07-01

    The AREVAs DMT process is a preventive chemical cleaning of the steam generators (SG) that provides the required features to keep the SG in good operative conditions. -Very low carbon steel corrosion -Innocuous towards stainless steel and nickel base alloys -Inherently safe process -Efficient magnetite dissolution -No use of CMR (i.e Carcinogenic, Mutagenic and toxic to Reproduction) Chemicals (e. g. Hydrazine) -No ammonia emissions -Easy decomposition of waste Several applications have been performed world-wide over the last 5 years. The results were fully satisfying in all the above stated points. The removal of up to 800 kg of dry deposits per SG was realized. A positive effect on fouling factor was observed, showing that AREVAs DMT process is a safe, easy and successful way to maintain the steam generators in excellent operative conditions. (Author)

  1. AREVA: from speech to reality / The example uranium mines in Niger; AREVA: du discours a la realite / L'exemple des mines d'uranium du Niger

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-01-15

    This document presents the activities of AREVA in Niger in the field of uranium production on different sites. It recalls the interventions by the CRIIRAD in support of a local NGO, the reactions of AREVA and some means of intimidation used by this company. It outlines, criticizes and discusses the contamination of water resources and, therefore their degradation, the contamination of air by radioactive dusts and gases from the production sites, the retailing of contaminated scrap metals, and the dispersal of radioactive materials in the environment (including a hospital), and also the outdoor storage of radioactive materials. It mentions some accidents which occurred during radioactive material transport, relates uranium exploitation with the greenhouse gas effect. It stresses that public hygiene is insufficient. It discusses the current prospecting works, and finally identifies guarantees to be obtained and urgent actions to be undertaken

  2. AREVA Technical Days (ATD) session 3: operations of the reactors and services division, technical and economic aspects; AREVA Technical Days (ATD) session 3: les activites du pole reacteurs et services, aspects techniques et economiques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    These technical days organized by the Areva Group aims to explain the group activities in a technological and economic point of view, to provide an outlook of worldwide energy trends and challenges and to present each of their businesses in a synthetic manner. This third session deals with the reactors technologies basics, the EPR and SWR 1000 issues and outlook, the nuclear systems of the future, the business opportunities and business models. (A.L.B.)

  3. Radioactivity and radioprotection: the every day life in a nuclear installation. Press tour at CEA/GRENOBLE 18 november 1999; Radioactivite et radioprotection: la vie quotidienne dans une installation nucleaire. Voyage de presse au Centre CEA/CADARACHE 18 novembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    In the framework of the public information, this paper gives a general information on the radioactivity and the radioprotection at the CEA/Cadarache center. A first part is devoted to a presentation of the radioactivity with definitions and radiation effects on the human being and the environment. An other part presents the radioprotection activities and regulations. The last part deals with specific activities of the CEA/Cadarache: the CASCAD installations for spent fuels storage, the LECA Laboratory for the Examination of Active Fuels and a dismantling installation for big irradiated objects. Historical aspects of the CEA/Cadarache are also provided. (A.L.B.)

  4. EPZ and AREVA. A longstanding partnership for the safe and reliable operation of the Dutch Borssele nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Broy, Yvonne [AREVA GmbH, Erlangen (Germany); Linger, Monique [Elektriciteits-Productiemaatschappij Zuid-Nederland N.V., Borssele (Netherlands)

    2014-04-15

    After 40 years of service, it belongs to the safest 25 % of all light-water reactors in the western hemisphere thanks to continuous modernization. In doing so, Borssele is setting standards for maintenance and upgrades. In view of the continuation of operation until 2034, further comprehensive modernization projects are planned. The plant operator, the Dutch N.V. Elektriciteitsproduktiemaatschappij (EPZ), decided to tackle this challenge with the support of its long-standing partner AREVA. Another milestone is coming up soon: The safety I and C shall gradually be changed to digital technology in the next years. Apart from close cooperation in plant technology, EPZ and AREVA also cooperate in fuel supply, as well as in the area of service and maintenance work. (orig.)

  5. New Method for Hard Sludge Removal from Tube Plate Surfaces: The AREVA Enhanced Inner Bundle Lancing Process

    Energy Technology Data Exchange (ETDEWEB)

    Stoss, J.; Santibanez, M.

    2014-07-01

    AREVA is currently conducting the final steps to start-up an enhanced technology to remove hard sludge deposits from the inner bundle area of the tube sheets. This inner bundle area at the top of the tube plate is the location with the lowest flow velocity of the circulating water at the secondary closed loop. The reduced water speed causes increased accumulation of ferrite oxides at these locations. (Author)

  6. Inquiry in the public interest, held at Cadarache into the construction of the reactor 'Jules Horowitz' and the problems related to the public dialogue; L'enquete d'utilite publique sur la creation du 'reacteur Jules Horowitz' a Cadarache et la participation locale

    Energy Technology Data Exchange (ETDEWEB)

    Bottiglioni, F

    2007-07-15

    In this paper are presented the main points of the inquiry taken by an official board into the demand of the Cea to create a new research tool, the 'Jules Horowitz Reactor', in its research center of Cadarache. The increasing involvement of the people in the decision-making procedures dealing with important projects is summed up, so as the distinctive features of the different regulations that frame the public participation are stressed. Some improvements are suggested to carry through next inquiries faster and more easily. The participation of the public has been low: only 11 people or associations have left their remarks to the inquiry members despite the large audience that attended the different meetings and debates organized on the issue by the CNDP (national board for public debate)

  7. CEA and AREVA HTR fuel particles manufacturing and characterization R and D Program

    Energy Technology Data Exchange (ETDEWEB)

    Charollais, F.; Perez, M.; Fonquernie, S.; Ablitzer, C.; Duhart, A.; Perrais, C.; Dugne, O.; Guillermier, P.; Harbonnier, G

    2004-07-01

    Worldwide, renewal of interest for High Temperature Reactors (HTR) moderated by graphite, using helium gas as coolant is due to the possibility offered by HTR technology to build small competitive modular units (100-300 MWe) and to produce high temperature gas required for hydrogen production or heat production. In this context, Commissariat a l'Energie Atomique (CEA) supported by AREVA, conducts R and D projects on HTR, which one is the mastering of the UO{sub 2} TRISO fuel fabrication technology including innovating prospects. The first step of the work is to recover fabrication know-how and to improve fabrication processes (for preparing the erection of a fuel pilot manufacture line of HTR particles). The second step will be the manufacturing of HTR fuel elements in purpose of irradiation tests. This publication deals with the know-how recovery and improved processes of UO{sub 2} TRISO manufacture, i.e. kernel and coatings manufacturing, the development of innovative characterization methods, a modelling approach of CVD processes and the status of the future laboratory manufacture line. Alternative fuel designs are also investigated, for instance the way of manufacturing UCO and UC{sub x} kernels with higher refractory coating material such as ZrC. (authors)

  8. Task Order 22 – Engineering and Technical Support, Deep Borehole Field Test. AREVA Summary Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Denton, Mark A. [AREVA Federal Services, Charlotte, NC (United States)

    2016-01-19

    Under Task Order 22 of the industry Advisory and Assistance Services (A&AS) Contract to the Department of Energy (DOE) DE-NE0000291, AREVA has been tasked with providing assistance with engineering, analysis, cost estimating, and design support of a system for disposal of radioactive wastes in deep boreholes (without the use of radioactive waste). As part of this task order, AREVA was requested, through a letter of technical direction, to evaluate Sandia National Laboratory’s (SNL’s) waste package borehole emplacement system concept recommendation using input from DOE and SNL. This summary review report (SRR) documents this evaluation, with its focus on the primary input document titled: “Deep Borehole Field Test Specifications/M2FT-15SN0817091” Rev. 1 [1], hereafter referred to as the “M2 report.” The M2 report focuses on the conceptual design development for the Deep Borehole Field Test (DBFT), mainly the test waste packages (WPs) and the system for demonstrating emplacement and retrieval of those packages in the Field Test Borehole (FTB). This SRR follows the same outline as the M2 report, which allows for easy correlation between AREVA’s review comments, discussion, potential proposed alternatives, and path forward with information established in the M2 report. AREVA’s assessment focused on three primary elements of the M2 report: the conceptual design of the WPs proposed for deep borehole disposal (DBD), the mode of emplacement of the WP into DBD, and the conceptual design of the DBFT. AREVA concurs with the M2 report’s selection of the wireline emplacement mode specifically over the drill-string emplacement mode and generically over alternative emplacement modes. Table 5-1 of this SRR compares the pros and cons of each emplacement mode considered viable for DBD. The primary positive characteristics of the wireline emplacement mode include: (1) considered a mature technology; (2) operations are relatively simple; (3) probability of a

  9. Task Order 22 – Engineering and Technical Support, Deep Borehole Field Test. AREVA Summary Review Report

    Energy Technology Data Exchange (ETDEWEB)

    Denton, Mark A. [AREVA Federal Services, Charlotte, NC (United States)

    2016-01-19

    Under Task Order 22 of the industry Advisory and Assistance Services (A&AS) Contract to the Department of Energy (DOE) DE-NE0000291, AREVA has been tasked with providing assistance with engineering, analysis, cost estimating, and design support of a system for disposal of radioactive wastes in deep boreholes (without the use of radioactive waste). As part of this task order, AREVA was requested, through a letter of technical direction, to evaluate Sandia National Laboratory’s (SNL’s) waste package borehole emplacement system concept recommendation using input from DOE and SNL. This summary review report (SRR) documents this evaluation, with its focus on the primary input document titled: “Deep Borehole Field Test Specifications/M2FT-15SN0817091” Rev. 1 [1], hereafter referred to as the “M2 report.” The M2 report focuses on the conceptual design development for the Deep Borehole Field Test (DBFT), mainly the test waste packages (WPs) and the system for demonstrating emplacement and retrieval of those packages in the Field Test Borehole (FTB). This SRR follows the same outline as the M2 report, which allows for easy correlation between AREVA’s review comments, discussion, potential proposed alternatives, and path forward with information established in the M2 report. AREVA’s assessment focused on three primary elements of the M2 report: the conceptual design of the WPs proposed for deep borehole disposal (DBD), the mode of emplacement of the WP into DBD, and the conceptual design of the DBFT. AREVA concurs with the M2 report’s selection of the wireline emplacement mode specifically over the drill-string emplacement mode and generically over alternative emplacement modes. Table 5-1 of this SRR compares the pros and cons of each emplacement mode considered viable for DBD. The primary positive characteristics of the wireline emplacement mode include: (1) considered a mature technology; (2) operations are relatively simple; (3) probability of a

  10. Phase 1A Final Report for the AREVA Team Enhanced Accident Tolerant Fuels Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Morrell, Mike E. [AREVA Federal Services LLC, Charlotte, NC (United States)

    2015-03-19

    In response to the Department of Energy (DOE) funded initiative to develop and deploy lead fuel assemblies (LFAs) of Enhanced Accident Tolerant Fuel (EATF) into a US reactor within 10 years, AREVA put together a team to develop promising technologies for improved fuel performance during off normal operations. This team consisted of the University of Florida (UF) and the University of Wisconsin (UW), Savannah River National Laboratory (SRNL), Duke Energy and Tennessee Valley Authority (TVA). This team brought broad experience and expertise to bear on EATF development. AREVA has been designing; manufacturing and testing nuclear fuel for over 50 years and is one of the 3 large international companies supplying fuel to the nuclear industry. The university and National Laboratory team members brought expertise in nuclear fuel concepts and materials development. Duke and TVA brought practical utility operating experience. This report documents the results from the initial “discovery phase” where the team explored options for EATF concepts that provide enhanced accident tolerance for both Design Basis (DB) and Beyond Design Basis Events (BDB). The main driver for the concepts under development were that they could be implemented in a 10 year time frame and be economically viable and acceptable to the nuclear fuel marketplace. The economics of fuel design make this DOE funded project very important to the nuclear industry. Even incremental changes to an existing fuel design can cost in the range of $100M to implement through to LFAs. If this money is invested evenly over 10 years then it can take the fuel vendor several decades after the start of the project to recover their initial investment and reach a breakeven point on the initial investment. Step or radical changes to a fuel assembly design can cost upwards of $500M and will take even longer for the fuel vendor to recover their investment. With the projected lifetimes of the current generation of nuclear power

  11. AREVA Technical Days (ATD) session 2: operations of the back-end of the nuclear fuel cycle; AREVA Technical Days (ATD) session 2: les activites du pole Aval du cycle du combustible nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    These technical days organized by the Areva Group aims to explain the group activities in a technological and economic point of view, to provide an outlook of worldwide energy trends and challenges and to present each of their businesses in a synthetic manner. This second session deals with the reprocessing business, back-end financing mechanisms, technology transfer, environmental management, risk management programs, research and development contribution to waste volume reductions, issues and outlook of nuclear wastes, comparison of the open and closed cycles. (A.L.B.)

  12. AREVA announces US$ 7.75 Per share friendly cash offer for UraMin; Offre publique d'achat amicale d'AREVA sur UraMin sur la base d'un prix de 7,75US$ par action

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    AREVA and UraMin Inc. ('UraMin') entered on June 15, 2007 into an agreement in respect of AREVA's friendly cash offer for 100% of the share capital of UraMin. UraMin is listed in London (AIM) and Toronto (TSX). AREVA (Euronext Paris) already owns 5.5% of UraMin's share capital. This cash offer of AREVA will be made through its indirect wholly-owned subsidiary CFMM Development ('AREVA') based on a price of US$ 7.75 per UraMin share. The total offer consideration amounts to more than USD 2.5 billion for 100% of the fully diluted share capital of UraMin. This represents a premium of 21% over UraMin 20-day weighted average trading price ending on June 8, 2007. The UraMin Board of Directors, after consulting with its financial advisors, has determined that the offer is fair and in the best interest of the UraMin shareholders and it has resolved to recommend acceptance of the Offer. BMO Capital Markets has provided an opinion that the offer is fair, from a financial point of view, to the UraMin shareholders. In connection with the offer, all directors and certain other shareholders representing approximately 25% of the outstanding UraMin shares (calculated on a fully diluted basis) have entered into lock-up agreements with AREVA pursuant to which they have agreed to tender all their UraMin shares to AREVA's offer. The support agreement entered into between AREVA and UraMin provides for, among other things, in case a superior proposal is accepted by UraMin, a right to match in favour of AREVA. The support agreement also includes a break up fee in favour of AREVA of US$ 75 million under certain circumstances. Concurrently with the closing of the proposed offer, UraMin will declare a dividend payable in shares of the capital of Niger Uranium Limited held by UraMin (where permitted by law) or a cash equivalent of the value of such shares.

  13. Hemisphere jet mass distribution at finite Nc

    Directory of Open Access Journals (Sweden)

    Yoshikazu Hagiwara

    2016-05-01

    Full Text Available We perform the leading logarithmic resummation of nonglobal logarithms for the single-hemisphere jet mass distribution in e+e− annihilation including the finite-Nc corrections. The result is compared with the previous all-order result in the large-Nc limit as well as fixed-order perturbative calculations.

  14. The tele-robotics system MT200-TAO replaces mechanical tele-manipulators in COGEMA/AREVA-La Hague hot cells

    Energy Technology Data Exchange (ETDEWEB)

    Garrec, Philippe; Lamy-Perbal, Sylvie; Friconneau, Jean-Pierre [CEA France (France); Piolain, Gerard [COGEMA/AREVA-Hague (France)

    2006-07-01

    We present here for the first time the tele-robotics system for hot-cells MT200-TAO (TAO stands for Teleoperation Assistee par Ordinateur or Computer Assisted Tele-robotics), able to replace a conventional telescopic medium tele-manipulator (extension 4 m; capacity 20 kg). The system is currently under evaluation in COGEMA/AREVA- La Hague hot-cells. (authors)

  15. EnviroAtlas - Durham, NC - Demo (Parent)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset is the base layer for the Durham, NC EnviroAtlas Area. The block groups are from the US Census Bureau and are included/excluded based on...

  16. NC METHOD FOR GENERATION OF CONJUGATINGHYPOID GEARS BASED ON NC'S FLEXIBILITY

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    It is known that manufacture of hypoid gears is difficult and complicated, the reason lies on the limitation of traditional mechanical machine tools. With the development of NC machine tools, there should be new ways of cutting this kind of gear. Therefore, an idea to generate gears with conjugating tooth surfaces is proposed, based on the "flexibility" characteristic of NC that means various motions, in a sense, can be performed arbitrarily on NC machine tools. Using this method, the direction of the contact path on tooth surfaces can be controlled, and also, theoretically, the generated tooth surfaces can transmit motion at specific transmission ratio curve.

  17. NC/NG与ADN的相互作用%Interaction of NG/NC with ADN

    Institute of Scientific and Technical Information of China (English)

    张腊莹; 衡淑云; 刘子如; 张皋; 赵凤起; 谭惠民

    2009-01-01

    用高压差示扫描量热法(PDSC),热重-微商热重法(TG-DTG),研究了双基粘合剂(NC/NG体系)与二硝酰胺铵(ADN)之间的相互作用.结果表明,(NC/NG)/ADN体系中NG的分解峰由NC/NG中的207.0 ℃提前至159.8 ℃,在高压下该分解峰温提前至153.6 ℃.NC/ADN的分解峰温比NG/ADN提前了4.8 ℃,而且大部分的ADN没有被NG加速而提前分解,表明NC对ADN的作用比NG更强烈.此外,还用真空安定性试验(VST)评价了NC/NG与ADN的相容性,混合体系的净增放气量大于11 mL,属于严重不相容,证明在90 ℃下NC/NG与ADN之间也存在强烈的相互作用.

  18. Heavy ion irradiation induced dislocation loops in AREVA's M5 Registered-Sign alloy

    Energy Technology Data Exchange (ETDEWEB)

    Hengstler-Eger, R.M., E-mail: Rosmarie.Hengstler-Eger@areva.com [AREVA, AREVA NP GmbH, Paul-Gossen-Str. 100, 91052 Erlangen (Germany); Baldo, P. [Argonne National Laboratory, Materials Science Division, 9700 South Cass Avenue, 60439 Argonne IL (United States); Beck, L. [Maier-Leibnitz-Laboratorium (MLL), Am Coulombwall 6, 85748 Garching (Germany); Dorner, J.; Ertl, K. [Max-Planck-Institut fuer Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Hoffmann, P.B. [AREVA, AREVA NP GmbH, Paul-Gossen-Str. 100, 91052 Erlangen (Germany); Hugenschmidt, C. [Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II), Lichtenbergstr. 1, 85747 Garching (Germany); Kirk, M.A. [Argonne National Laboratory, Materials Science Division, 9700 South Cass Avenue, 60439 Argonne IL (United States); Petry, W.; Pikart, P. [Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II), Lichtenbergstr. 1, 85747 Garching (Germany); Rempel, A. [AREVA, AREVA NP GmbH, Paul-Gossen-Str. 100, 91052 Erlangen (Germany)

    2012-04-15

    Pressurized water reactor (PWR) Zr-based alloy structural materials show creep and growth under neutron irradiation as a consequence of the irradiation induced microstructural changes in the alloy. A better scientific understanding of these microstructural processes can improve simulation programs for structural component deformation and simplify the development of advanced deformation resistant alloys. As in-pile irradiation leads to high material activation and requires long irradiation times, the objective of this work was to study whether ion irradiation is an applicable method to simulate typical PWR neutron damage in Zr-based alloys, with AREVA's M5 Registered-Sign alloy as reference material. The irradiated specimens were studied by electron backscatter diffraction (EBSD), positron Doppler broadening spectroscopy (DBS) and in situ transmission electron microscopy (TEM) at different dose levels and temperatures. The irradiation induced microstructure consisted of - and -type dislocation loops with their characteristics corresponding to typical neutron damage in Zr-based alloys; it can thus be concluded that heavy ion irradiation under the chosen conditions is an excellent method to simulate PWR neutron damage.

  19. NC10 bacteria in marine oxygen minimum zones

    DEFF Research Database (Denmark)

    Padilla, Cory C; Bristow, Laura A; Sarode, Neha

    2016-01-01

    Bacteria of the NC10 phylum link anaerobic methane oxidation to nitrite denitrification through a unique O2-producing intra-aerobic methanotrophy pathway. A niche for NC10 in the pelagic ocean has not been confirmed. We show that NC10 bacteria are present and transcriptionally active in oceanic....... rRNA and mRNA transcripts assignable to NC10 peaked within the OMZ and included genes of the putative nitrite-dependent intra-aerobic pathway, with high representation of transcripts containing the unique motif structure of the nitric oxide (NO) reductase of NC10 bacteria, hypothesized...

  20. Narrow gap mechanised arc welding in nuclear components manufactured by AREVA NP; Le soudage mecanise a l'arc en chanfrein etroit dans les constructions nucleaires realisees par AREVA NP

    Energy Technology Data Exchange (ETDEWEB)

    Peigney, A. [Departement Soudage AREVA Centre Technique - 71380 Saint-Marcel (France)

    2007-07-01

    Nuclear components require welds of irreproachable and reproducible quality. Moreover, for a given welding process, productivity requirements lead to reduce the volume of deposited metal and thus to use narrow gap design. In the shop, narrow gap Submerged Arc Welding process (SAW) is currently used on rotating parts in flat position for thicknesses up to 300 mm. Welding is performed with one or two wires in two passes per layer. In Gas Tungsten Arc Welding process (GTAW), multiple applications can be found because this process presents the advantage of allowing welding in all positions. Welding is performed in one or two passes per layer. The process is used in factory and on the nuclear sites for assembling new components but also for replacing components and for repairs. Presently, an increase of productivity of the process is sought through the use of hot wire and/or two wires. Concerning Gas Metal Arc Welding process (GMAW), its use is growing for nuclear components, including narrow gap applications. This process, limited in its applications in the past on account of the defects it generated, draws benefit from the progress of the welding generators. Then it is possible to use this efficient process for high security components such as those of nuclear systems. It is to be noted that the process is applicable in the various welding positions as it is the case for GTAW, while being more efficient than the latter. This paper presents the state of the art in the use of narrow gap mechanised arc welding processes by AREVA NP units. (author) [French] Les constructions nucleaires necessitent des soudures de qualite irreprochable et reproductible. Par ailleurs les imperatifs de productivite conduisent, pour un procede donne, a reduire le volume de metal a deposer et donc a utiliser des chanfreins etroits. En atelier, le soudage fil-flux en chanfrein etroit est couramment utilise sur des pieces tournantes en position a plat pour des epaisseurs atteignant 300 mm. On

  1. DIWA trademark. AREVA's approach of intelligent computer-aided support of water chemistry monitoring in power plants

    Energy Technology Data Exchange (ETDEWEB)

    Fandrich, Joerg [AREVA NP GmbH, Erlangen (Germany)

    2011-07-01

    The complexity of power plant operation makes stringent demands on the chemical quality of the coolant in process systems and loops. Optimal water chemistry ensures high corrosion resistance of these systems and is thus essential for safe and economic long term plant operation. The market offers a huge variety of commercial software packages for water chemistry control. Most of these computer programs have to be considered as data analysis or, respectively, data acquisition programs. Some of them require manual data input (Laboratory Information Management Systems), others are capable of performing a fully automated data acquisition. However, the plant operator typically is left alone with the actual interpretation of all collected and validated data, which would be the main characteristic feature of an analysis (or monitoring) system. The data validation is typical being performed by means of numerical methods in the broadest sense. This activity requires a long working experience and specific skills by the plant chemistry operator. True diagnostic systems need to be significantly more advanced. They contain the capability of data interpretation and derivation of specific diagnoses. This is combined with additional explanations on how the diagnoses were derived. Additionally, further recommendations are offered on how to proceed to reach the normal operational behavior as soon as possible. AREVA's DIWA trademark system features a fuzzy logic expert system that is based on expert knowledge. It is built on symptoms, which are combined in rules as part of the fuzzy tool set. These components can be edited without programming knowledge, which significantly reduces training efforts. It makes the system more robust, more compact and simpler compared to other so-called expert systems. DIWA trademark represents the knowledge in a natural way, in which other conventional expert system may have difficulties or need a larger set of rule algorithms. (orig.)

  2. Dynamic characteristics of NC table with SVD

    Institute of Scientific and Technical Information of China (English)

    Linhong WANG; Bo WU; Runsheng DU; Shuzi YANG

    2008-01-01

    This paper employs the SVD (singular value decomposition) method to study dynamic characteristics of a numerical control (NC) table. Acceleration signals of the NC table at three directions are tested; the singular spectrum of the signals is acquired with SVD; principal components of the signals are found out; dynamic char-acteristics of the signals and their contributing factors are studied by extracting dynamic characteristics of principal components; and signals and principal components are quantitatively analyzed by calculating signal energy. Results indicate that signal characteristics of the previous two principal components are apparent, based on which dynamic characteristics of chaotic signal can be extracted. Signal at the perpendicular direction of the table is signifi-cantly correlated with that at the horizontal motion dir-ection, which indicates that they are excited from the same vibration source. However, signals perpendicular to each other in terms of the motion direction at the horizontal level are rarely correlated; the total signal energy is max-imum at the motion direction, minimum at the horizontal non-motion direction, and medium at the perpendicular non-motion direction. Bending vibration of the lead screw at the perpendicular direction is far more violent than that at the horizontal direction.

  3. 76 FR 49664 - Drawbridge Operation Regulation; Beaufort Channel, Beaufort, NC

    Science.gov (United States)

    2011-08-11

    ... deviation is necessary to accommodate racing participants for the ``Neuse Riverkeeper Foundation Sprint..., at Beaufort, NC. The bike route of the ``Neuse Riverkeeper Foundation Sprint Triathlon'' crosses...

  4. DRIVE AND CONTROL OF VIRTUAL-AXIS NC MACHINE TOOLS

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The structure features and driving modes of virtual-axis NC machine tools are studied.Accor- ding to different application requirements,the three-axis control method,the five-axis control method and the six-freedom control method are put forward.These results lay a foundation for the product development of the virtual-axis NC machine tools.

  5. On pseudorandom generators in NC0

    DEFF Research Database (Denmark)

    Cryan, Mary; Miltersen, Peter Bro

    2001-01-01

    In this paper we consider the question of whether NC 0 circuits can generate pseudorandom distributions. While we leave the general question unanswered, we show – • Generators computed by NC 0 circuits where each output bit depends on at most 3 input bits (i.e, DNC 3 0 circuits) and with stretch...

  6. ncRNA consensus secondary structure derivation using grammar strings.

    Science.gov (United States)

    Achawanantakun, Rujira; Sun, Yanni; Takyar, Seyedeh Shohreh

    2011-04-01

    Many noncoding RNAs (ncRNAs) function through both their sequences and secondary structures. Thus, secondary structure derivation is an important issue in today's RNA research. The state-of-the-art structure annotation tools are based on comparative analysis, which derives consensus structure of homologous ncRNAs. Despite promising results from existing ncRNA aligning and consensus structure derivation tools, there is a need for more efficient and accurate ncRNA secondary structure modeling and alignment methods. In this work, we introduce a consensus structure derivation approach based on grammar string, a novel ncRNA secondary structure representation that encodes an ncRNA's sequence and secondary structure in the parameter space of a context-free grammar (CFG) and a full RNA grammar including pseudoknots. Being a string defined on a special alphabet constructed from a grammar, grammar string converts ncRNA alignment into sequence alignment. We derive consensus secondary structures from hundreds of ncRNA families from BraliBase 2.1 and 25 families containing pseudoknots using grammar string alignment. Our experiments have shown that grammar string-based structure derivation competes favorably in consensus structure quality with Murlet and RNASampler. Source code and experimental data are available at http://www.cse.msu.edu/~yannisun/grammar-string.

  7. Advances and Future Issues for STEP-compliant NC Manufacture

    Institute of Scientific and Technical Information of China (English)

    LIU Riliang; ZHANG Chengrui; NEWMAN Stephen T

    2006-01-01

    Over the last years a new data model, known as STEP-NC, has been proposed and accepted as an international standard (ISO 14649) to replace ISO 6983 (G&M code programming). STEP-NC enables bi-directional communication of high-level geometric and manufacturing information, and provides a way of interoperable and adaptable NC manufacturing of mechanical components. This paper starts with an overview of the STEP-NC data model, provides a brief review of the global research and development activities, and tries to identify the issues and challenges for the application of the new standard and the implementation of related systems. This paper also provides a vision of the STEP-compliant NC manufacturing and the development trends of related technologies and systems, focusing on STEP-compliant CNCs.

  8. Non-leptonic kaon decays at large $N_c$

    CERN Document Server

    Donini, A; Pena, C; Romero-López, F

    2016-01-01

    We study the scaling with the number of colours, $N_c$, of the weak amplitudes mediating kaon mixing and decay. We evaluate the amplitudes of the two relevant current-current operators on the lattice for $N_c=3-7$. We conclude that the subleading $1/N_c$ corrections in $\\hat{B}_K$ are small, but those in the $K \\rightarrow \\pi\\pi$ amplitudes are large and fully anti-correlated in the $I=0, 2$ isospin channels. We briefly comment on the implications for the $\\Delta I=1/2$ rule.

  9. Lattice study of large $N_c$ QCD

    CERN Document Server

    DeGrand, Thomas

    2016-01-01

    We present a lattice simulation study of large $N_c$ regularities of meson and baryon spectroscopy in $SU(N_c)$ gauge theory with two flavors of dynamical fundamental representation fermions. Systems investigated include $N_c=2$, 3, 4, and 5, over a range of fermion masses parametrized by a squared pseudoscalar to vector meson mass ratio between about 0.2 to 0.7. Good agreement with large $N_c$ scaling is observed in the static potential, in meson masses and decay constants, and in baryon spectroscopy.

  10. Dynamic characteristics of an NC table with phase space reconstruction

    Institute of Scientific and Technical Information of China (English)

    Linhong WANG; Bo WU; Runsheng DU; Shuzi YANG

    2009-01-01

    The dynamic properties of a numerical control (NC) table directly interfere with the accuracy and surface quality of work pieces machined by a computer numerical control (CNC) machine. Phase space reconstruction is an effective approach for researching dynamic behaviors of a system with measured time series. Based on the theory and method for phase space reconstruction, the correlation dimension, maximum Lyapunov exponent, and dynamic time series measured from the NC table were analyzed. The characteristic quantities such as the power spectrum, phase trajectories, correlation dimension, and maximum Lyapunov exponent are extracted from the measured time series. The chaotic characteristic of the dynamic properties of the NC table is revealed via various approaches.Therefore, an NC table is a nonlinear dynamic system. This research establishes a basis for dynamic system discrimi-nation of a CNC machine.

  11. Research on Visual Virtual Design Platform for NC Machine Tools

    Institute of Scientific and Technical Information of China (English)

    HU Rufu; CHEN Xiaoping; SUN Qinghong

    2006-01-01

    The fundamental ideas on building the collaborative design platform of virtual visualization for NC machine tools are introduced. The platform is based on the globally shared product model conforming to the STEP Standard, and used PDM system to integrate and encapsulate CAD/CAE and other application software for the product development. The platform also integrated the expert system of NC machine tools design, analysis and estimation. This expert system utilized fuzzy estimation principle to evaluate the design and simulation analysis results and make decisions. The platform provides the collaborative intelligent environment for the design of virtual NC machine tools prototype aiming at integrated product design team. It also supports the customized development of NC machine tools.

  12. Large-Nc Gauge Theory and Chiral Random Matrix Theory

    Science.gov (United States)

    Hanada, Masanori; Lee, Jong-Wan; Yamada, Norikazu

    Effective theory approaches and the large-Nc limit are useful for studying the strongly coupled gauge theories. In this talk we consider how the chiral random matrix theory (χRMT) can be used in the study of large-Nc gauge theories. It turns out the parameter regions, in which each of these two approaches are valid, are different. Still, however, we show that the breakdown of chiral symmetry can be detected by combining the large-Nc argument and the χRMT with some cares. As a demonstration, we numerically study the four dimensional SU(Nc) gauge theory with Nf = 2 heavy adjoint fermions on a 24 lattice by using Monte-Carlo simulations, which is related to the infinite volume lattice through the Eguchi-Kawai equivalence.

  13. Observations of NC stop nets for bottlenose dolphin takes

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To observe the NC stop net fishery to document the entanglement of bottlenose dolphins and movement of dolphins around the nets.

  14. 77 FR 33997 - Television Broadcasting Services; Greenville, NC

    Science.gov (United States)

    2012-06-08

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Greenville, NC AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: The Commission has before it a petition for rulemaking filed...

  15. Synthesis, thermolysis, and sensitivities of HMX/NC energetic nanocomposites.

    Science.gov (United States)

    Wang, Yi; Song, Xiaolan; Song, Dan; Liang, Li; An, Chongwei; Wang, Jingyu

    2016-07-15

    1,3,5,7-Tetranittro-1,3,5,7-tetrazocane/nitrocellulose (HMX/NC) nanocomposites were successfully synthesized by an improved sol-gel-supercritical method. NC nanoparticles with a size of ∼30nm were cross-linked to form a network structure, and HMX nanoparticles were imbedded in the nano-NC matrix. The key factors, i.e., the selection of catalyst and solvent, were probed. No phase transformation of the HMX occurred before or after fabrication, and the molecular structures of the HMX and NC did not change. Thermal analyses were performed, and the kinetic and thermodynamic parameters, such as activation energy (EK), per-exponent factor (lnAK), rate constant (k), activation heat (ΔH(≠)), activation free energy (ΔG(≠)), activation entropy (ΔS(≠)), critical temperature of thermal explosion (Tb), and critical heating rate of thermal explosion (dT/dt)Tb, were calculated. The results indicate that HMX/NC presented a much lower activation energy (165.03kJ/mol) than raw HMX (282.5kJ/mol) or raw NC (175.51kJ/mol). The chemical potential (ΔG(≠)) for the thermal decomposition of HMX/NC has a positive value, which means that the activation of the molecules would not proceed spontaneously. The significantly lower ΔH(≠) value of HMX/NC, which represents the heat needed to be absorbed by an explosive molecule to change it from its initial state to an activated state, implies that the molecules of HMX/NC are much easier to be activated than those of raw HMX. Similarly, the HMX/NC presented a much lower Tb (168.2°C) than raw HMX (283.2°C). From the results of the sensitivity tests, the impact and friction sensitivities of HMX/NC were significantly decreased compared with those of raw HMX, but the thermal sensitivity was distinctly higher. The activation of the particles under external stimulation was simulated, and the mechanism was found to be crucial. Combining the thermodynamic parameters, the mechanism as determined from the results of the sensitivity tests was

  16. precision deburring using NC and robot equipment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1980-05-01

    Deburring precision miniature components is often time consuming and inconsistent. Although robots are available for deburring parts, they are not precise enough for precision miniature parts. Numerical control (NC) machining can provide edge break consistencies to meet requirements such as 76.2-..mu..m maximum edge break (chamfer). Although NC machining has a number of technical limitations which prohibits its use on many geometries, it can be an effective approach to features that are particularly difficult to deburr.

  17. Nonlinear Absorption Properties of nc-Si:H Thin Films

    Institute of Scientific and Technical Information of China (English)

    GUO Zhenning; GUO Hengqun; LI Shichen; HUANG Yongzhen; WANG Qiming

    2001-01-01

    It is reported in this paper that the phenomenon of the saturated absorption of the exciton in hydrogenated nanocrystalline silicon (nc-Si:H) thin film fabricated by plasma enhanced chemical vapor deposition (PECVD) without any post-processing is observed at room temperature using pump-probe technology. This nonlinear optical absorption property is induced by the surface effect of the silicon nanoparticles in nc-Si:H thin films.

  18. The charge storage of the nc-Si layer

    Institute of Scientific and Technical Information of China (English)

    戴敏; 张林; 鲍云; 石建军; 陈铠; 李伟; 黄信凡; 陈坤基

    2002-01-01

    Sandwiched structures (a-SiNx/a-Si/a-SiNx) have been fabricated by the plasma enhanced chemical vapour deposi-tion technique. A Si nanocrystal (nc-Si) layer was formed by crystallization of an a-Si layer according to the constrainedcrystallization principle after quasi-static thermal annealing at 1100℃ for 30min. Transmission electron microscopy(TEM) and Raman scattering spectroscopy clearly demonstrated that nc-Si grains were formed in the as-deoositeda-Si layer after annealing. The density of nc-Si grains is about 1011cm-2 as shown by TEM photograplasx Usingcapacitance-voltage (C-V) measurements we investigated the electrical characteristics of the sandwiched structures.The charge storage phenomenon of the nc-Si layer was observed from the shift of flat-band voltage (VFB) in C-V curvesat a high frequency (1 MHz). We estimated the density of nc-Si grains to be about 1011cm-2 from the shift value ofVFB, which is in agreement with the result of TEM photographs. At the same time, we found that the shift of VFBincreased with the increase of the applied constant dc voltage or the thickness of the nc-Si layer.

  19. Nc-Si Thin Film Deposited at Low Temperature and Nc-Si Heterojunction Solar Cell

    Institute of Scientific and Technical Information of China (English)

    赵占霞; 崔容强; 孟凡英; 于化丛; 周之斌

    2004-01-01

    This paper reported some results about intrinsic nanocrystalline silicon thin films deposited by high frequency (HF) sputtering on p-type c-Si substrates at low temperature. Samples were examined by atomic force microscopy (AFM), X-ray diffraction (XRD), infrared absorption, and ellipsometry. XRD measurements show that this film has a new microstructure, which is different from the films deposited by other methods. The ellipsometry result gives that the optical band gap of the film is about 2.63 eV. In addition, the n-type nc-Si ∶ H/p-type c-Si heterojunction solar cell, which has open circuit voltage (Uoc) of 558 mV and short circuit current intensity (Isc) of 29 mA/cm2, was obtained based on the nanocrystalline silicon thin film. Irradiated under AM1.5, 100 mW/cm2 light intensity, the Uoc, Isc, and FF can keep stable for 10 h.

  20. Change-management. From commercial power operation to post power operation and decommissioning; Change-Management. Vom Leistungsbetrieb ueber den Nachbetrieb zum Rueckbau. T. 1. Stilllegung und Rueckbau von Reaktoren und Anlagen im Brennstoffkreislauf durch AREVA

    Energy Technology Data Exchange (ETDEWEB)

    Wasinger, Karl [AREVA GmbH, Offenbach am Main (Germany)

    2015-02-15

    Transition from power generation to decommissioning challenges utilities. Power generation is mainly characterized by a stable working environment and constant workload, decommissioning and dismantling, however, by transformation and change. Also, changing requirements for the workforce's skills challenge the organization and its senior management. Ensuring effective and efficient performance, while maintaining motivation of staff, requires adjustment of management processes as well as of operational organization and human resources management. AREVA has more than 20 years of experience in decommissioning of own nuclear fuel cycle plants in France, as well as of other large plants and power reactors in Germany, the United Kingdom and the US. Therefore, the group has developed and successfully implemented integrated change management processes. The implementation of well-established and proven methods, developed by the productive industry and adjusted to the nuclear regulatory requirements, significantly improves the performance and efficiency of means and methods in use. The AREVA Performance Improvement Process defines concrete approaches to identify and improve potential deficits of productivity in six main areas (decommissioning scenarios and stra-tegies, waste treatment and logistics, operations management, supply chain, regulatory monitoring and controls as well as dismantling operation). Nuclear plant and facility owners around the world benefit from AREVA experts well experienced in execution of large and complex decommissioning projects.

  1. Non-global logarithms at finite Nc beyond leading order

    CERN Document Server

    Khelifa-Kerfa, Kamel

    2015-01-01

    We analytically compute non-global logarithms at finite Nc fully up to 4 loops and partially at 5 loops, for the hemisphere mass distribution in e+e- to di-jets to leading logarithmic accuracy. Our method of calculation relies solely on integrating the eikonal squared-amplitudes for the emission of soft energy-ordered real-virtual gluons over the appropriate phase space. We show that the series of non-global logarithms in the said distribution exhibits a pattern of exponentiation thus confirming - by means of brute force - previous findings. In the large-Nc limit, our results coincide with those recently reported in literature. A comparison of our proposed exponential form with all-orders numerical solutions is performed and the phenomenological impact of the finite-Nc corrections is discussed.

  2. Eikonal gluon bremsstrahlung at finite Nc beyond two loops

    Science.gov (United States)

    Delenda, Yazid; Khelifa-Kerfa, Kamel

    2016-03-01

    We present a general formalism for computing the matrix-element squared for the emission of soft energy-ordered gluons beyond two loops in QCD perturbation theory at finite Nc. Our formalism is valid in the eikonal approximation. A Mathematica program has been developed for the automated calculation of all real/virtual eikonal squared amplitudes needed at a given loop order. For the purpose of illustration, we show the explicit forms of the eikonal squared amplitudes up to the fifth-loop order. In the large-Nc limit, our results coincide with those previously reported in literature.

  3. Eikonal gluon radiation at finite-Nc beyond 2 loops

    CERN Document Server

    Khelifa-Kerfa, Kamel

    2015-01-01

    We present first calculations of QCD matrix-elements in perturbation theory at finite Nc beyond 2 loops in the eikonal approximation for e+ e- annihilation processes. For the emission of n soft energy-ordered gluons we solve both the colour and kinematic structures at a given order in perturbation theory by means of a Mathematica program that relies solely on a recently developed Mathematica code, ColorMath, that evaluates the trace of products of colour matrices. At large Nc, our squared amplitudes reduce to those already known in the literature.

  4. Exact symmetry of large $N_{c}$ QCD

    CERN Document Server

    Page, P R

    1999-01-01

    QCD and QED exhibit an infinite set of three-point Green's functions that contain only OZI rule violating contributions, and (for QCD) vanish exactly in the large N_c limit. This is due to symmetrization, do not follow from any Lagrangian symmetry, and constitutes the discovery of a new symmetry principle in QCD and QED. We prove that the amplitude for a neutral hybrid {1,3,5...}^{-+} exotic current to create eta pi0 vanishes exactly for QCD in the large N_c limit. Crystal Barrel's experimental claim of a resonant 1^{-+} decaying to eta pi0 suggests that the 1^{-+} is not a hybrid meson.

  5. Highly conducting and preferred oriented boron doped nc-Si films for window layers in nc-Si solar cells

    Science.gov (United States)

    Mondal, Praloy; Das, Debajyoti

    2016-05-01

    Growth and optimization of the boron dopednanocrystalline silicon (nc-Si) films have been studied by varyingthe gaspressure applied to the hydrogendiluted silane plasma in RF (13.56 MHz) plasma-enhanced chemical vapor deposition (PECVD) system, using diborane (B2H6) as the dopant gas. High magnitudeof electrical conductivity (~102 S cm-1) andorientedcrystallographic lattice planes have been obtained with high crystalline volume fraction (~86 %) at an optimum pressure of 2.5 Torr. XRD and Raman studies reveal good crystallinity with preferred orientation, suitable for applications in stacked layer devices, particularly in nc-Si solar cells.

  6. Post occupancy survey of the Arizona LEED NC population

    Science.gov (United States)

    Oates, Hugo Dixon

    Existing green building literature has not provided conclusive performance results for energy efficiency, water efficiency and the utilization and proper management of green building features. The few existing energy performance studies had not represented a significant portion of a population, were not random samples, did not included many structures from hot and dry climates and had generated heavily debated results. This thesis examines the fifty-three buildings comprising the Arizona Leadership in Energy and Environmental Design for New Construction (LEED NC) building population and in doing so hypothesizes that Arizona's LEED NC buildings achieve expected energy and water performance and exhibit various energy efficiency correlations. The thesis also establishes a baseline understanding of Arizona's LEED NC population characteristics. Data collection efforts were successful for all desired deliverables with the exception of water performance metrics. Energy analysis results rejected the energy efficiency hypotheses by returning greater energy use intensities than the non-LEED national building stock as well as the design and baseline energy use simulations. The energy correlation analysis returned statistically significant results for a single system attribute and several managerial attributes. The results suggest that the LEED NC rating system requires immediate reevaluation to ensure future green building success in Arizona.

  7. Large $N_{c}$ in chiral perturbation theory

    CERN Document Server

    Kaiser, R

    2000-01-01

    The construction of the effective Lagrangian relevant for the mesonic sector of QCD in the large N_c limit meets with a few rather subtle problems. We thoroughly examine these and show that, if the variables of the effective theory are chosen suitably, the known large N_c counting rules of QCD can unambiguously be translated into corresponding counting rules for the effective coupling constants. As an application, we demonstrate that the Kaplan-Manohar transformation is in conflict with these rules and is suppressed to all orders in 1/N_c. The anomalous dimension of the axial singlet current generates an additional complication: The corresponding external field undergoes nonmultiplicative renormalization. As a consequence, the Wess-Zumino-Witten term, which accounts for the U(3)_R x U(3)_L anomalies in the framework of the effective theory, contains pieces that depend on the running scale of QCD. The effect only shows up at nonleading order in 1/N_c, but requires specific unnatural parity contributions in the...

  8. 77 FR 56250 - North Carolina Disaster #NC-00044

    Science.gov (United States)

    2012-09-12

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION North Carolina Disaster NC-00044 AGENCY: U.S. Small Business Administration. ACTION: Notice... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  9. 76 FR 38018 - Safety Zone, Newport River; Morehead City, NC

    Science.gov (United States)

    2011-06-29

    ... standards are technical standards (e.g., specifications of materials, performance, design, or operation... in the Federal Register (33 FR 165). We received no comments on the proposed rule. No public meeting... Transportation awarded a contract to Astron General Contracting Company of Jacksonville, NC to perform...

  10. Large Nc volume reduction and chiral random matrix theory

    CERN Document Server

    Lee, Jong-Wan; Yamada, Norikazu

    2013-01-01

    Motivated by recent progress on the understanding of the Eguchi-Kawai (EK) volume equivalence and growing interest in conformal window, we simultaneously use the large-Nc volume reduction and Chiral Random Matrix Theory (chRMT) to study the chiral symmetry breaking of four dimensional SU(Nc) gauge theory with adjoint fermions in the large Nc limit. Although some cares are required because the chRMT limit and 't Hooft limit are not compatible in general, we show that the breakdown of the chiral symmetry can be detected in large-Nc gauge theories. As a first step, we mainly focus on the quenched approximation to establish the methodology. We first confirm that heavy adjoint fermions, introduced as the center symmetry preserver, work as expected and thanks to them the volume reduction holds. Using massless overlap fermion as a probe, we then calculate the low-lying Dirac spectrum for fermion in the adjoint representation to compare to that of chRMT, and find that chiral symmetry is indeed broken in the quenched ...

  11. TwNC: a Multifaceted Dutch News Corpus

    NARCIS (Netherlands)

    Ordelman, Roeland; Jong, de Franciska; Hessen, van Arjan; Hondorp, Hendri

    2007-01-01

    This contribution describes the Twente News Corpus (TwNC), a multifaceted corpus for Dutch that is being deployed in a number of NLP research projects among which tracks within the Dutch national research programme MultimediaN, the NWO programme CATCH, and the Dutch-Flemish programme STEVIN. The de

  12. 78 FR 72009 - Establishment of Class E Airspace; Star, NC

    Science.gov (United States)

    2013-12-02

    ... Federal Register a notice of proposed rulemaking to establish Class E airspace at Star, NC (78 FR 54413... Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565,...

  13. 77 FR 46631 - Television Broadcasting Services; Greenville, NC

    Science.gov (United States)

    2012-08-06

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Greenville, NC AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: The Commission has before it a petition for rulemaking filed by...

  14. The biodistribution of NC100668 and the effect of excess NC100668 on the biodistribution and kidney retention of {sup 99m}Tc-NC100668 in the rat

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, David [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom)]. E-mail: davidedwards@ge.com; Lewis, Joanne [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Battle, Mark [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Lear, Rochelle [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Farrar, Gill [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Barnett, David J. [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Godden, Vanessa [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Edwards, Catherine [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Oliveira, Alexandra [Research and Development, GE Healthcare Bio-Sciences, Grove Centre, HP7 9LL Amersham (United Kingdom); Ahlstroem, Hakan [Institution of Oncology, Radiology and Clinical Immunology, Section of Radiology, Uppsala University Hospital, SE-751 85 Uppsala (Sweden)

    2007-04-15

    Introduction: {sup 99m}Tc-NC100668 is being developed to aid the diagnosis of thromboemboli. The purpose of this study was to investigate if the presence of excess NC100668 interferes with the biodistribution and blood clot uptake of {sup 99m}Tc-NC100668. The secondary aim was to investigate the causes underlying the kidney retention of {sup 99m}Tc-NC100668. Methods: The uptake of a {sup 14}C-labelled analogue of NC100668, as well as {sup 99m}Tc-NC100668, into plasma (in vitro) and blood (in vivo) clots was determined. The biodistribution of {sup 99m}Tc-NC100668 at a range of NC100668 doses was studied in normal Wistar rats and those bearing experimentally induced deep venous thrombosis. The biodistribution of a negative control peptide and {sup 99m}Tc-NC100668 plus L-lysine was studied in healthy male Wistar rats. Results: The biodistribution as well as plasma clot uptake of [Asn-U-{sup 14}C]NC100668 and {sup 99m}Tc-NC100668 was similar. Apart from some reduction in kidney retention, the biodistribution and uptake of radioactivity into the blood clot were not significantly affected by the presence of up to 1000 times the clinical dose of NC100668. Kidney retention of radioactivity could be more effectively reduced by coadministration of 889 {mu}g/kg NC100668 than 450 mg/kg L-lysine. A negative control peptide with no affinity for FXIIIa demonstrated very little kidney retention. Conclusions: The biodistribution and blood clot uptake of {sup 99m}Tc-NC100668 and [Asn-U-{sup 14}C]NC100668 are similar. With the exception of the kidneys, {sup 99m}Tc-NC100668 biodistribution and blood clot uptake are unaffected by the presence of unlabelled NC100668. The kidney retention of radioactivity is probably due to transglutaminase activity and, to a lesser extent, nonspecific charge-mediated endocytosis.

  15. Topics on heavy baryon chiral perturbation theory in the large N_c limit

    CERN Document Server

    Flores-Mendieta, R

    2002-01-01

    We compute nonanalytical pion-loop corrections to baryon masses in a combined expansion in chiral symmetry breaking and 1/N_c, where N_c is the number of colors. Specifically, we compute flavor-27 baryon mass splittings at leading order in chiral perturbation theory. Our results, at the physical value N_c=3, are compared with the expressions obtained in heavy baryon chiral perturbation theory with no 1/N_c expansion.

  16. Series Design of Large-Scale NC Machine Tool

    Institute of Scientific and Technical Information of China (English)

    TANG Zhi

    2007-01-01

    Product system design is a mature concept in western developed countries. It has been applied in war industry during the last century. However, up until now, functional combination is still the main method for product system design in China. Therefore, in terms of a concept of product generation and product interaction we are in a weak position compared with the requirements of global markets. Today, the idea of serial product design has attracted much attention in the design field and the definition of product generation as well as its parameters has already become the standard in serial product designs. Although the design of a large-scale NC machine tool is complicated, it can be further optimized by the precise exercise of object design by placing the concept of platform establishment firmly into serial product design. The essence of a serial product design has been demonstrated by the design process of a large-scale NC machine tool.

  17. Large Nc from Seiberg–Witten curve and localization

    Directory of Open Access Journals (Sweden)

    Jorge G. Russo

    2015-09-01

    Full Text Available When N=2 gauge theories are compactified on S4, the large Nc limit then selects a unique vacuum of the theory determined by saddle-point equations, which remains determined even in the flat-theory limit. We show that exactly the same equations can be reproduced purely from Seiberg–Witten theory, describing a vacuum where magnetically charged particles become massless, and corresponding to a specific degenerating limit of the Seiberg–Witten spectral curve where 2Nc−2 branch points join pairwise giving aDn=0, n=1,…,Nc−1. We consider the specific case of N=2 SU(Nc SQCD coupled with 2Nf massive fundamental flavors. We show that the theory exhibits a quantum phase transition where the critical point describes a particular Argyres–Douglas point of the Riemann surface.

  18. NC-Audit: Auditing for Network Coding Storage

    CERN Document Server

    Le, Anh

    2012-01-01

    Network coding-based storage has recently received a lot of attention thanks to its ability to efficiently repair failed nodes. Independently, another body of work has proposed integrity checking schemes for cloud storage, none of which, however, is customized for network coding storage or can efficiently support repair. In this work, we bridge the gap between these currently disconnected bodies of work, and we focus on the (novel) advantage of network coding for integrity checking. We propose NC-Audit - a remote data integrity checking scheme, designed specifically for network coding-based storage cloud. NC-Audit provides a unique combination of desired properties: (i) efficient checking of data integrity (ii) efficient support for repairing failed nodes (iii) full support for modification of outsourced data and (iv) protection against information leakage when checking is performed by a third party. The key ingredient of the design of NC-Audit is a novel combination of SpaceMac, a homomorphic MAC scheme for ...

  19. Identification and characterization of a microneme protein (NcMIC6) in Neospora caninum.

    Science.gov (United States)

    Li, Wensheng; Liu, Jing; Wang, Jing; Fu, Yong; Nan, Huizhu; Liu, Qun

    2015-08-01

    Neospora caninum, an Apicomplexa parasite, is the causative agent of neosporosis. As described for other members of Apicomplexa, microneme proteins (MICs) play a key role in attachment and invasion of host cells by N. caninum. Herein we identified N. caninum microneme protein 6 (NcMIC6) that is orthologous to Toxoplasma gondii microneme protein 6 (TgMIC6). The open reading frame of the NcMIC6 gene is 984 bp and encodes a 327 amino acid peptide. Sequence analysis showed that NcMIC6 included a signal peptide, a transmembrane region, three epidermal growth factor-like (EGF) domains, and two low complexity regions. Antibodies raised against recombinant NcMIC6 recognized an approximately 35-kDa native MIC6 protein in Western blots of N. caninum tachyzoites. Immunofluorescence analysis showed that NcMIC6 had a polar labeling pattern, which was consistent with localization of micronemes in the apical region. Pulse invasion assays showed that NcMIC6 translocated from the apical tip to the posterior end of the parasites. Secretion assays demonstrated that NcMIC6 was released into the supernatants. Importantly, it was clearly revealed by co-immunoprecipitation that NcMIC6 formed a complex with other two soluble microneme proteins (NcMIC1 and NcMIC4). In conclusion, identification and characterization of the novel microneme protein NcMIC6 may contribute to understanding how this protein functions during the parasite motility and host cell invasion.

  20. Molecular Dynamics Simulation of NC/NG Blends%NC/NG共混体系的分子动力学模拟研究

    Institute of Scientific and Technical Information of China (English)

    齐晓飞; 张晓宏; 李吉祯; 刘芳莉; 宋振伟; 张军平

    2013-01-01

    为研究复合改性双基推进剂(CMDB)基体硝化纤维素(NC)与硝化甘油(NG)之间相互作用的实质,通过构建NC纯物质以及不同质量比的NC/NG共混体系模型,并采用分子动力学模拟的方法,对NC分子链的回转半径及模型中不同原子间的径向分布函数进行了分析.结果发现:NC分子链的回转半径随温度升高而增大的趋势并不明显;而随NG分子数量增多而增大的趋势非常显著.径向分布函数分析表明,NG分子可与NC分子形成氢键而替代NC分子内的氢键,使NC分子内的相互作用力减弱,从而导致NC分子链回转半径增大.%In order to explore the interaction between nitrocellulose (NC) and nitroglycerine (NG) of composite modified double-base (CMDB) propellants, the radius of gyration of NC molecules and radial distribution function for different atoms of NC and NC/NG blends were calculated by using molecular dynamics simulation ( MD) . It was found that the radius of gyration of NC molecules was independent on the temperature, while the number of NG molecules increased greatly with temperature. Besides, according to the radial distribution function of the models, it was revealed that the H-bond could be formed between NG and NC molecules instead of H-bond in the individual NC molecule, which could decrease the interaction force inside NC molecules, thus increase the radius of gyration of NC.

  1. Generation and immunity testing of a recombinant adenovirus expressing NcSRS2-NcGRA7 fusion protein of bovine Neospora caninum.

    Science.gov (United States)

    Jia, Li-Jun; Zhang, Shou-Fa; Qian, Nian-Chao; Xuan, Xue-Nan; Yu, Long-Zheng; Zhang, Xue-Mei; Liu, Ming-Ming

    2013-04-01

    Neospora caninum is the etiologic agent of bovine neosporosis, which affects the reproductive performance of cattle worldwide. The transmembrane protein, NcSRS2, and dense-granule protein, NcGRA7, were identified as protective antigens based on their ability to induce significant protective immune responses in murine neosporosis models. In the current study, NcSRS2 and NcGRA7 genes were spliced by overlap-extension PCR in a recombinant adenovirus termed Ad5-NcSRS2-NcGRA 7, expressing the NcSRS2-NcGRA7 gene, and the efficacy was evaluated in mice. The results showed that the titer of the recombinant adenovirus was 10(9)TCID50/ml. Three weeks post-boost immunization (w.p.b.i.), the IgG antibody titer in sera was as high as 1:4,096. IFN-γ and IL-4 levels were significantly different from the control group (P<0.01). This research established a solid foundation for the development of a recombinant adenovirus vaccine against bovine N. caninum.

  2. NC green roof stormwater quantity and quality field evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Moran, A.; Hunt, B.; Jennings, G. [North Carolina State Univ., Raleigh, NC (United States). Dept. of Biological and Agricultural Engineering

    2004-07-01

    A study was conducted in an effort to establish design standards for green roofs in North Carolina (NC). It was conducted in light of recent regulations that require stormwater runoff to be treated by structural controls in urban development. Two extensive green roofs were constructed within the Neuse River Basin in order to estimate the per cent of precipitation retained by the green roof; estimate the per cent peak flow reduction; determine whether green roofs can be used as nutrient reduction best management practices (BMPs) and if so, what removal efficiency should be assigned to green roofs; identify green roof vegetation types that thrive in central and eastern NC and find an optimal depth of soil for desirable plant growth. The determining factors for greater water retention were found to be soil depth and plant selection. BMPs such as bioretention areas, wet and dry detention ponds, constructed wetlands, and sand filters are commonly seen throughout NC. A new option for BMPs is the green roof to use thousands of square feet available on rooftops that would not otherwise be available on the ground. Each green roof in this study retained about 60 per cent of the total recorded rainfall during a nine-month observation period. The average peak flow reduction for both green roofs was about 85 per cent. Water quality data indicated that higher concentrations of total nitrogen and total phosphorous were present in the green roof runoff than in the control roof runoff and in the rainfall at each green roof site. This may be a result of N and P leaching from the soil media, which was composed of 15 per cent compost. It was suggested that leaching could be reduced with less organic matter present in the soil media. 12 refs., 1 tab., 8 figs.

  3. CNC LATHE MACHINE PRODUCING NC CODE BY USING DIALOG METHOD

    Directory of Open Access Journals (Sweden)

    Yakup TURGUT

    2004-03-01

    Full Text Available In this study, an NC code generation program utilising Dialog Method was developed for turning centres. Initially, CNC lathes turning methods and tool path development techniques were reviewed briefly. By using geometric definition methods, tool path was generated and CNC part program was developed for FANUC control unit. The developed program made CNC part program generation process easy. The program was developed using BASIC 6.0 programming language while the material and cutting tool database were and supported with the help of ACCESS 7.0.

  4. Contaminant-mobilizing capability of fullerene nanoparticles (nC60): Effect of solvent-exchange process in nC60 formation.

    Science.gov (United States)

    Wang, Lilin; Fortner, John D; Hou, Lei; Zhang, Chengdong; Kan, Amy T; Tomson, Mason B; Chen, Wei

    2013-02-01

    Fullerene nanoparticles (nC(60)) in aqueous environments can significantly enhance the transport of hydrophobic organic contaminants by serving as a contaminant carrier. In the present study, the authors examine the effect of the solvent-exchange process on nC(60) aggregate formation and, subsequently, on nC(60) 's contaminant-mobilizing capability. A series of nC(60) samples were prepared using a modified toluene-water solvent-exchange method through the inclusion of a secondary organic solvent in the phase transfer of molecular C(60) in toluene to nC(60) in water. Two groups of solvents--a water-miscible group and a non-water-miscible group-of varied polarity were selected as secondary solvents. The involvement of a secondary solvent in the phase transfer process had only small effects on the particle size and distribution, ζ potential, and mobility of the nC(60) products but significantly influenced the capability of nC(60) to enhance the transport of 2,2',5,5'-polychlorinated biphenyl (PCB) in a saturated sandy soil column, regardless of whether the secondary solvent was water-miscible or non-water-miscible. The two groups of secondary solvents appear to affect the aggregation properties of nC(60) in water via different mechanisms. In general, nC(60) products made with a secondary water-miscible solvent have stronger capabilities to enhance PCB transport. Taken together, the results indicate that according to formation conditions and solvent constituents, nC(60) will vary significantly in its interactions with organic contaminants, specifically as related to adsorption or desorption as well as transport in porous media.

  5. smyRNA: a novel Ab initio ncRNA gene finder.

    Directory of Open Access Journals (Sweden)

    Raheleh Salari

    Full Text Available BACKGROUND: Non-coding RNAs (ncRNAs have important functional roles in the cell: for example, they regulate gene expression by means of establishing stable joint structures with target mRNAs via complementary sequence motifs. Sequence motifs are also important determinants of the structure of ncRNAs. Although ncRNAs are abundant, discovering novel ncRNAs on genome sequences has proven to be a hard task; in particular past attempts for ab initio ncRNA search mostly failed with the exception of tools that can identify micro RNAs. METHODOLOGY/PRINCIPAL FINDINGS: We present a very general ab initio ncRNA gene finder that exploits differential distributions of sequence motifs between ncRNAs and background genome sequences. CONCLUSIONS/SIGNIFICANCE: Our method, once trained on a set of ncRNAs from a given species, can be applied to a genome sequences of other organisms to find not only ncRNAs homologous to those in the training set but also others that potentially belong to novel (and perhaps unknown ncRNA families. AVAILABILITY: (http://compbio.cs.sfu.ca/taverna/smyrna.

  6. ISO 14649 (STEP-NC: New Standards for CNC Machining

    Directory of Open Access Journals (Sweden)

    Yusri Yusof

    2010-06-01

    Full Text Available The changing economic climate has made global manufacturing a growing reality over the last decade, forcing companies from east and west and all over the world to collaborate beyond geographic boundaries in the design, manufacture and assemble of products. The ISO10303 and ISO14649 Standards (STEP and STEP-NC have been developed to introduce interoperability into manufacturing enterprises so as to meet the challenge of responding to production on demand. The paper focuses on the use of this new standard to address the process planning and machining of turn/mill discrete components. Due to the complexity of programming these machines there is a need to model their process capability to improve the interoperable manufacturing capability in places such as turning centres. Finally a proposed computational environment for a STEP-NC compliant system for turning operations (SCSTO is described. And supported by the specification of information models and constructed using a structured methodology and object-oriented methods. SCSTO was developed to generate a Part 21 file based on machining features to support the interactive generation of process plans utilizing feature extraction. A case study component has been developed to prove the concept for using the milling and turning parts of ISO14649 to provide a turn-mill CAD/CAPP/CAM environment.

  7. Study of an NC system of machining crown gears

    Science.gov (United States)

    Xu, Xiaogang; Wang, Huaqing; Yan, Jian; Gao, Shenyou

    2005-12-01

    Crown gear couplings are usually used in metallurgy and steel rolling equipments, which is manufactured by duplicating processing in common. The method makes the manipulator work hard, and the efficiency is low. The machining precision is limited to the shape of the mold and it is difficult to control the movement of machines table. This work stated an NC system to use hobbing machine. It consists of an industrial control computer, grating sensor, servo- motor and its driver source, servo driver card and other I/O equipments of inputting and outputting. The grating sensor was installed in the axial direction to trace the instantaneous position of gob rest. The radial movement of the machine table was controlled by a servomotor. When the computer captures the axial signal, this system controls the machine table by moving ahead or backwards according to the calculated value of interpolation theory. Thus, two dimensions (axial and radial) associated movement was realized while the crown gear was processed. The feature of the system is that a grating sensor used in the axial direction replaces the servomotor. By making a little change in the mechanism of the machine, NC can be implement and its redesign cost is very low. The design software has an interpolation function for a circular arc and line. The system has been used on a Y1380 gear hobbing machine, and the correlative software of machining crown gear has been designed as well. Satisfactory results have been obtained, showing facility and reliability in practical operation.

  8. 牛源犬新孢子虫NcSRS2-NcGRA7融合基因的克隆与生物信息学分析%Cloning and bioinformatics analysis of NcSRS2-NcGRA7 fusion gene of bovine Neospora caninum

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发; 谷振甲

    2013-01-01

    为了解牛源犬新孢子虫NcSRS2-NcGRA7融合基因的生物学特性,本试验提取牛源犬新孢子虫基因组DNA,应用PCR技术扩增犬新孢子虫表面蛋白基因NcSRS2和致密颗粒蛋白基因NcGRA7,SOE-PCR技术拼接NcSRS2和NcGRA7基因,构建NcSRS2-NcGRA7融合基因重组克隆质粒,并进行PCR鉴定、双酶切鉴定及生物信息学分析.结果,NcSRS2基因扩增片段大小为1 061 bp,NcGRA7基因扩增片段大小为364 bp,NcSRS2-NcGRA7融合基因扩增片段大小为1 482 bp;获得重组克隆质粒pMD18-NcSRS2-NcGRA7经PCR鉴定、双酶切鉴定正确;测序分析表明,与Gen-Bank中已发表的美国株犬新孢子虫(AF061249、AF176649)核苷酸序列同源性为99%;经DNAman等软件分析,预测NcSRS2-NcGRA7融合蛋白抗原指数较高,融合蛋白二级结构以α-螺旋和β-折叠为主,三级结构中2种蛋白独立折叠,并借助Linker互相连接,功能互不影响.本试验为牛源犬新孢子虫NcSRS2-NcGRA7融合蛋白的免疫学研究奠定了基础.%In order to understand the biological characteristic of NcSRS2-NcGRA7 fusion gene of bovine Neospora Caninum,genomic DNA of N.caninum was extracted.The surface protein gene NcSRS2 and granule protein gene NcGRA7 were amplified by PCR,respectively.Nc-SRS2-NcGRA7 fusion gene was synthesized by SOE-PCR.The NcSRS2-NcGRA7 cloning vector was constructed and identified by PCR amplification,double digestion and bioinformatic analysis.The results showed that the sizes of NcSRS2,NcGRA7 and NcSRS2-NcGRA7 were 1061 bp,364 bp and 1482 bp,respectively.The cloning vector was demonstrated to be correct by PCR and double digestion.Sequencing analysis showed that the nucleotide sequences of NcSRS2 and NcGRA7 shared 99% homology with those published in GenBank (AF061249,AF176649).Prediction analysis by DNAman software indicated that the antigen index of NcSRS2-NcGRA7 was high.The main secondary structure of the fusion protein was mainly composed of α-helix and

  9. Construction of the Active Site of Metalloenzyme on Au NC Micelles

    Institute of Scientific and Technical Information of China (English)

    ZHANG, Zhiming; FU, Qiuan; HUANG, Xin; XU, Jiayun; LIU, Junqiu; SHEN, Jiacong

    2009-01-01

    For developing an efficient nanoenzyme system with self-assembly strategy, gold nanocrystal micelles (Au NC micelles) with inserted catalytic Zn(Ⅱ) centers were constructed by self-assembly of a catalytic ligand [N,N-bis(2-aminoethyl)-N'dodecylethylenediamine] Zn(Ⅱ) complexes (Zn(Ⅱ)L) on the surface of Au NC via hy- drophobic interaction. The functionalized Au NC micelles acted as an excellent nanoenzyme model for imitating ribonuclease. The catalytic capability of the Au NC micelles was evaluated by accelerating the cleavage of 2-hydroxypropyl p-nitrophenyl phosphate (HPNP). These functionalized Au NC micelles exhibited considerable ri- bonuclease-like activities by a factor of 4.9×104 (kcat/kuncat) for the cleavage of HPNP in comparison to the sponta- neous cleavage of HPNP at 37℃. The catalytic capability of the functionalized Au NC micelles can be considera- bly compared to other models reported previously as nanoenzymes under the comparable conditions.

  10. The Nc dependencies of baryon masses: Analysis with Lattice QCD and Effective Theory

    Energy Technology Data Exchange (ETDEWEB)

    Calle Cordon, Alvaro C. [JLAB; DeGrand, Thomas A. [University of Colorado; Goity, Jose L. [JLAB

    2014-07-01

    Baryon masses at varying values of Nc and light quark masses are studied with Lattice QCD and the results are analyzed in a low energy effective theory based on a combined framework of the 1/Nc and Heavy Baryon Chiral Perturbation Theory expansions. Lattice QCD results for Nc=3, 5 and 7 obtained in quenched calculations, as well as results for unquenched calculations for Nc=3, are used for the analysis. The results are consistent with a previous analysis of Nc=3 LQCD results, and in addition permit the determination of sub-leading in 1/Nc effects in the spin-flavor singlet component of the baryon masses as well as in the hyperfine splittings.

  11. Characterizing ncRNAs in human pathogenic protists using high-throughput sequencing technology

    Directory of Open Access Journals (Sweden)

    Lesley Joan Collins

    2011-12-01

    Full Text Available ncRNAs are key genes in many human diseases including cancer and viral infection, as well as providing critical functions in pathogenic organisms such as fungi, bacteria, viruses and protists. Until now the identification and characterization of ncRNAs associated with disease has been slow or inaccurate requiring many years of testing to understand complicated RNA and protein gene relationships. High-throughput sequencing now offers the opportunity to characterize miRNAs, siRNAs, snoRNAs and long ncRNAs on a genomic scale making it faster and easier to clarify how these ncRNAs contribute to the disease state. However, this technology is still relatively new, and ncRNA discovery is not an application of high priority for streamlined bioinformatics. Here we summarize background concepts and practical approaches for ncRNA analysis using high-throughput sequencing, and how it relates to understanding human disease. As a case study, we focus on the parasitic protists Giardia lamblia and Trichomonas vaginalis, where large evolutionary distance has meant difficulties in comparing ncRNAs with those from model eukaryotes. A combination of biological, computational and sequencing approaches has enabled easier classification of ncRNA classes such as snoRNAs, but has also aided the identification of novel classes. It is hoped that a higher level of understanding of ncRNA expression and interaction may aid in the development of less harsh treatment for protist-based diseases.

  12. NC flame pipe cutting machine tool based on open architecture CNC system

    Institute of Scientific and Technical Information of China (English)

    Xiaogen NIE; Yanbing LIU

    2009-01-01

    Based on the analysis of the principle and flame movement of a pipe cutting machine tool, a retrofit NC flame pipe cutting machine tool (NFPCM) that can meet the demands of cutting various pipes is proposed. The paper deals with the design and implementation of an open architecture CNC system for the NFPCM, many of whose aspects are similar to milling machines; however, different from their machining processes and control strategies. The paper emphasizes on the NC system structure and the method for directly creating the NC file according to the cutting type and parameters. Further, the paper develops the program and sets up the open and module NC system.

  13. A New Approach For FEM Simulation of NC Machining Processes

    Science.gov (United States)

    Wang, Sheng Ping; Padmanaban, Shivakumar

    2004-06-01

    The paper describes a new method for a finite element based pseudo-simulation of Numerically Controlled (NC) machining (material removal) processes. Industrial machining of a component usually results in warping or distortion due to the re-establishment of equilibrium in the retained part along with the relief of the insitu residual stresses in the removed part. In many cases, these distortions can be so large that the part may no longer be able to serve its designated functionality. Considering that the machining process is fundamentally a material removal process, a new method based on an automated removal of finite elements in the cutting area has been developed in the finite element analysis (FEA) software MSC.Marc to conduct pseudo-simulation of the NC machining process., A number of key software enhancements have been made to facilitate the pseudo-simulation of the NC machining process. First, a seamless interface has been developed to import APT/CL data generated by CAD/CAM systems. Then, the cutting paths have been generated based on information in the APT/CL files and used for the automatic detection of the intersection between the cutter and the finite element mesh. With each incremental motion of the cutter, the FEA solver detects all the elements that are located within the cutting path. Such elements are then deactivated in a step-by-step manner that is consistent with the actual machining process. In order to improve the fidelity of the cut area, local adaptive mesh refinement in the vicinity of the cutting tool is undertaken. This enables relatively coarser meshes away from the cut area and provides more accurate representation of the actual volume that is removed. As demonstrated by an industrial example, the enhanced software features in MSC.Marc have made it possible to practically and efficiently analyze complex machining processes of 3D production parts and provide an elegant tool for predicting distortions in large structures due to the relief

  14. ncISO Facilitating Metadata and Scientific Data Discovery

    Science.gov (United States)

    Neufeld, D.; Habermann, T.

    2011-12-01

    Increasing the usability and availability climate and oceanographic datasets for environmental research requires improved metadata and tools to rapidly locate and access relevant information for an area of interest. Because of the distributed nature of most environmental geospatial data, a common approach is to use catalog services that support queries on metadata harvested from remote map and data services. A key component to effectively using these catalog services is the availability of high quality metadata associated with the underlying data sets. In this presentation, we examine the use of ncISO, and Geoportal as open source tools that can be used to document and facilitate access to ocean and climate data available from Thematic Realtime Environmental Distributed Data Services (THREDDS) data services. Many atmospheric and oceanographic spatial data sets are stored in the Network Common Data Format (netCDF) and served through the Unidata THREDDS Data Server (TDS). NetCDF and THREDDS are becoming increasingly accepted in both the scientific and geographic research communities as demonstrated by the recent adoption of netCDF as an Open Geospatial Consortium (OGC) standard. One important source for ocean and atmospheric based data sets is NOAA's Unified Access Framework (UAF) which serves over 3000 gridded data sets from across NOAA and NOAA-affiliated partners. Due to the large number of datasets, browsing the data holdings to locate data is impractical. Working with Unidata, we have created a new service for the TDS called "ncISO", which allows automatic generation of ISO 19115-2 metadata from attributes and variables in TDS datasets. The ncISO metadata records can be harvested by catalog services such as ESSI-labs GI-Cat catalog service, and ESRI's Geoportal which supports query through a number of services, including OpenSearch and Catalog Services for the Web (CSW). ESRI's Geoportal Server provides a number of user friendly search capabilities for end users

  15. An NC algorithm for recognizing tree adjoining languages

    Energy Technology Data Exchange (ETDEWEB)

    Pali, M.A. (New Jersey Institute of Technology, Newark, NJ (United States)); Shende, S.M. (Univ. of Nebraska, Lincoln, NE (United States))

    1992-04-01

    A parallel algorithm is presented for recognizing the class of languages generated by tree adjoining grammars, a tree rewriting system which has applications in natural language processing. This class of languages is known to properly include all context-free languages; for example, the noncontext-free sets [l brace]a'b'c[r brace] and [l brace]ww[r brace] are in this class. It is shown that the recognition problem for tree adjoining languages can be solved by a concurrent read, concurrent write parallel random-assess machine (CRCW PRAM) in O(log n) time using polynomially many processors. Thus, the class of tree adjoining languages is in AC[sup 1] and hence in NC. This extends a previous result for context-free languages.

  16. Study of Machining Error Forecast in NC Lathe

    Institute of Scientific and Technical Information of China (English)

    LIU Jiwei; ZHANG Ying; YANG Zheqing

    2006-01-01

    This paper brings forward a kind of machining error forecast principle in NC lathe simulation system. It combines the method of math, dynamic, material and mechanism, etc, sums up the factors which can affect the machining error, coalescent knowledge of mechanism manufacture technique and interconvert characteristic, mapped the change of physics factor in cutting process into virtual manufacture system by mathematical model. On the platform of Windows 2000 and Visual C++, applying program is developed by use of C++. The lean warehouse of MATLAB is transferred in order to command MATLAB on the language platform of MATLAB, and then the curve of the results is drawn by the outcome of calculation, which is based on the mathematical model in order to manifest the simulation results in the pattern of data and curve.

  17. NC-3智能快速充电器

    Institute of Scientific and Technical Information of China (English)

    于左

    2001-01-01

    @@ 使用数字照相机的人特别关心其电池充电设备的好坏.由于现在的可充电池的容量成倍增长,用老式的固定电流式充电器往往需要很长时间才能将电池充满;一般的快速充电器又容易将小容量的可充电池过量充电.笔者向大家介绍"三洋"公司出品的NC-3智能快速充电器.

  18. ncDNA and drift drive binding site accumulation

    Directory of Open Access Journals (Sweden)

    Ruths Troy

    2012-08-01

    Full Text Available Abstract Background The amount of transcription factor binding sites (TFBS in an organism’s genome positively correlates with the complexity of the regulatory network of the organism. However, the manner by which TFBS arise and accumulate in genomes and the effects of regulatory network complexity on the organism’s fitness are far from being known. The availability of TFBS data from many organisms provides an opportunity to explore these issues, particularly from an evolutionary perspective. Results We analyzed TFBS data from five model organisms – E. coli K12, S. cerevisiae, C. elegans, D. melanogaster, A. thaliana – and found a positive correlation between the amount of non-coding DNA (ncDNA in the organism’s genome and regulatory complexity. Based on this finding, we hypothesize that the amount of ncDNA, combined with the population size, can explain the patterns of regulatory complexity across organisms. To test this hypothesis, we devised a genome-based regulatory pathway model and subjected it to the forces of evolution through population genetic simulations. The results support our hypothesis, showing neutral evolutionary forces alone can explain TFBS patterns, and that selection on the regulatory network function does not alter this finding. Conclusions The cis-regulome is not a clean functional network crafted by adaptive forces alone, but instead a data source filled with the noise of non-adaptive forces. From a regulatory perspective, this evolutionary noise manifests as complexity on both the binding site and pathway level, which has significant implications on many directions in microbiology, genetics, and synthetic biology.

  19. Study on Interaction of ADN and (NC+NG) by Gasometric Method%量气法研究ADN与(NC+NG)的相互作用

    Institute of Scientific and Technical Information of China (English)

    何少蓉; 张林军; 衡淑云; 刘子如

    2008-01-01

    用 NBK型"拉瓦"量气测试系统研究了较高温度下二硝酰胺铵(ADN)与双基吸收药(NC+NG)体系的相互作用,从动力学角度阐述了二者的相互作用.结果表明: ADN与(NC+NG)混合物加热分解的最终放气量在标准状态下为626.8 mL·g-1,与ADN和(NC+NG)最大放气量之和相比并没有增加,但分解速度显著提高,活化能显著降低至82.58 kJ·mol-1,ADN与(NC+NG)之间存在强烈的相互作用.

  20. Study on Intelligent NC Programming for Complex Components of Marine Diesel Based on KBE and UG NX

    Institute of Scientific and Technical Information of China (English)

    ZHANG Liang; ZHANG Shengwen; FANG Xifeng

    2006-01-01

    The NC programming for complex components has lots drawbacks such as excessive repetitious labors, heavy workload and lack of optimization, which are especially serious in NC programming for complex components of marine diesel. Based on the key technologies of applying KBE(Knowledge Based Engineering)to NC programming--knowledge representation, generalized knowledge base, knowledge acquisition and knowledge reasoning, the system of intelligent NC programming for complex components of marine diesel has been built by means of the knowledge template and the UG/Open. The experiment results indicate that the NC program generated with high efficiency of NC programming by the system is accurate enough to meet the need of NC machining. Consequently, the automatization and intelligentization of NC programming has been presented, and the study is proved to be a successful attempt in the area of applying KBE to NC programming.

  1. NC++: a NOW-Based Object-Oriented Distributed Programming Language%基于NOW的对象式分布式程序设计语言NC++

    Institute of Scientific and Technical Information of China (English)

    顾庆; 谢立; 陈道蓄; 吴迎红; 孙钟秀

    2001-01-01

    An object-oriented distributed programming language NC++ which is based on NOW (network of workstations) environment is introduced in this paper. It is an extension of DC++. NC++ gives a rather complete programming environment, including NC++ pre-compiler, visual-programming interface, multicast communicating facility and a test system. It improves the process group management and inter-process communication facilities, and puts forth a DSM (distributed shared memory) subsystem based on belief network, which is used to manipulate C++ global variables. In practice, NC++ offers simplicity for distributed program design without sacrificing the performance.%提出了一个基于工作站网(network of workstations,简称NOW)的分布式程序设计语言NC++(NOW C++).它是DC++语言的扩充.NC++提供了一个完备的编程环境,包括NC++预编译器、图视编程界面、多目通信机制和测试系统.它完善了组管理机制和进程通信机制,提出了一个基于信度推理网络的分布共享内存(distributed shared memory,简称DSM)机制以管理C++公共变量.实践证明,NC++语言在确保编程方便性的前提下保证了分布式程序的性能.

  2. Concept of automatic programming of NC machine for metal plate cutting by genetic algorithm method

    Directory of Open Access Journals (Sweden)

    B. Vaupotic

    2005-12-01

    Full Text Available Purpose: In this paper the concept of automatic programs of the NC machine for metal plate cutting by genetic algorithm method has been presented.Design/methodology/approach: The paper was limited to automatic creation of NC programs for two-dimensional cutting of material by means of adaptive heuristic search algorithms.Findings: Automatic creation of NC programs in laser cutting of materials combines the CAD concepts, the recognition of features and creation and optimization of NC programs. The proposed intelligent system is capable to recognize automatically the nesting of products in the layout, to determine the incisions and sequences of cuts forming the laid out products. Position of incisions is determined at the relevant places on the cut. The system is capable to find the shortest path between individual cuts and to record the NC program.Research limitations/implications: It would be appropriate to orient future researches towards conceiving an improved system for three-dimensional cutting with optional determination of positions of incisions, with the capability to sense collisions and with optimization of the speed and acceleration during cutting.Practical implications: The proposed system assures automatic preparation of NC program without NC programer.Originality/value: The proposed concept shows a high degree of universality, efficiency and reliability and it can be simply adapted to other NC-machines.

  3. Anion-Dependent Aggregate Formation and Charge Behavior of Colloidal Fullerenes (n-C60)

    Science.gov (United States)

    The fate and transport of colloidal fullerenes (n-C60) in the environment is likely to be guided by electrokinetic and aggregation behavior. In natural water bodies inorganic ions exert significant effects in determining the size and charge of n-C60 nanoparticles. Although the ef...

  4. Process design for NC machining%数控加工的工艺设计

    Institute of Scientific and Technical Information of China (English)

    杨毅

    2001-01-01

    The steps of process design, details and main points of NC machining are introduced. The method of NC machining process design is presented.%重点介绍了数控加工工艺设计的步骤、内容和要点,提供了数控加工工艺设计的方法。

  5. 33 CFR 110.170 - Lockwoods Folly Inlet, N.C.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lockwoods Folly Inlet, N.C. 110.170 Section 110.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.170 Lockwoods Folly Inlet, N.C. (a)...

  6. Eta' Mass and Chiral Symmetry Breaking at Large Nc and Nf

    CERN Document Server

    Girlanda, L; Talavera, P

    2001-01-01

    We propose a method for implementing the large-Nc, large-Nf limit of QCD at the effective Lagrangian level. Depending on the value of the ratio Nf/Nc, different patterns of chiral symmetry breaking can arise, leading in particular to different behaviors of the eta-prime mass in the combined large-N limit.

  7. Thermal Safety Study on TEGDN/NG/NC Gun Propellant

    Science.gov (United States)

    Yi, J. H.; Zhao, F. Q.; Hu, R. Z.; Xue, L.; Xu, S. Y.

    2010-10-01

    The self-accelerating decomposition temperature (TSADT), critical temperature of thermal explosion (Tb), adiabatic time to explosion (tTIad), 50% drop height of impact sensitivity (H50), critical temperature of hot spot initiation caused by impact (Tcr,hotspot), safety degree (Sd), critical thermal explosion ambient temperature (Tacr), and thermal explosion probability (PTE) of the gun propellant composed of triethyleneglycol dinitrate (TEGDN), nitroglycerin (NG), and nitrocellulose (NC) were studied. The results of thermal safety evaluation on the gun propellant were obtained: (1) T00 = 433.4 K, TSADT = Te0 = 441.1 K, Tb = Tbp0 = 468.4 K; (2) when Ek = 205.3 × 103 J mol -1 and Ak = 1020.62 s -1, tTIad = 48.3 s, H50 = 17.93 cm, Tcr, hotspot = 634.9 K; for a sphere sample, TS(T)max = 369.0K, Tacr = 364.2 K, Sd = 65.03%, PTE = 34.96%.

  8. The NC16A domain of collagen XVII plays a role in triple helix assembly and stability.

    Science.gov (United States)

    Van den Bergh, Françoise; Fu, Chang-Ling; Olague-Marchan, Monica; Giudice, George J

    2006-12-01

    Collagen XVII/BP180 is a transmembrane constituent of the epidermal anchoring complex. To study the role of its non-collagenous linker domain, NC16A, in protein assembly and stability, we analyzed the following recombinant proteins: the collagen XVII extracellular domain with or without NC16A, and a pair of truncated proteins comprising the COL15-NC15 stretch expressed with or without NC16A. All four proteins were found to exist as stable collagen triple helices; however, the two missing NC16A exhibited melting temperatures significantly lower than their NC16A-containing counterparts. Protein refolding experiments revealed that the rate of triple helix assembly of the collagen model peptide GPP(10) is greatly increased by the addition of an upstream NC16A domain. In summary, the NC16A linker domain of collagen XVII exhibits a positive effect on both the rate of assembly and the stability of the adjoining collagen structure.

  9. Computational approaches for the analysis of ncRNA through Deep Sequencing techniques

    Directory of Open Access Journals (Sweden)

    Dario eVeneziano

    2015-06-01

    Full Text Available The majority of the human transcriptome is defined as non-coding RNA (ncRNA, since only a small fraction of human DNA encodes for proteins, as reported by the ENCODE project. Several distinct classes of ncRNAs, such as transfer RNA (tRNA, microRNA (miRNA, and long non-coding RNA (lncRNA, have been classified, each with its own three-dimensional folding and specific function. As ncRNAs are highly abundant in living organisms and have been discovered to play important roles in many biological processes, there has been an ever increasing need to investigate the entire ncRNAome in further unbiased detail.Recently, the advent of Next-Generation Sequencing (NGS technologies has substantially increased the throughput of transcriptome studies, allowing an unprecedented investigation of ncRNAs, as regulatory pathways and novel functions involving ncRNAs are now also emerging. The huge amount of transcript data produced by NGS has progressively required the development and implementation of suitable bioinformatics workflows, complemented by knowledge-based approaches, to identify, classify, and evaluate the expression of hundreds of ncRNAs in normal and pathological states, such as cancer.In this mini-review, we present and discuss current bioinformatics advances in the development of such computational approaches to analyze and classify the non-coding RNA component of human transcriptome sequence data obtained from NGS technologies.

  10. Springback of thin-walled tube NC precision bending and its numerical simulation

    Institute of Scientific and Technical Information of China (English)

    GU Rui-jie; YANG He; ZHAN Mei; LI Heng

    2006-01-01

    The springback is one of the key factors which affect the forming quality of thin-walled tube NC precision bending. The elastic-plastic finite element method was proposed to study the springback process of thin-walled tube NC precision bending and the combination of dynamic explicit algorithm and the static implicit algorithm was proposed to solve the whole process of thin-walled tube NC precision bending. Then,the 3D elastic-plastic finite element model was established based on the DYNAFORM platform,and the model was verified to be reasonable. At last,the springback rule of thin-walled tube NC precision bending and the effect of geometry and material parameters on the springback rule of thin-walled tube NC precision bending were studied,which is useful to controlling the springback of thin-walled tube NC precision bending,and the numerical simulation method can be used to study other effect of parameters on the forming quality of thin-walled tube NC precision bending.

  11. Process-scheme-driven automatic construction of NC machining cell for aircraft structural parts

    Institute of Scientific and Technical Information of China (English)

    Chen Shulin; Zheng Guolei; Zhou Min; Du Baorui; Chu Hongzhen

    2013-01-01

    In order to enhance the NC programming efficiency and quality of aircraft structural parts (ASPs), an intelligent NC programming pattern driven by process schemes is presented. In this pattern, the NC machining cell is the minimal organizational structure in the technological process, consisting of an operation machining volume cell, and the type and parameters of the machining operation. After the machining cell construction, the final NC program can be easily obtained in a CAD/CAM system by instantiating the machining operation for each machining cell. Accord-ingly, how to automatically establish the machining cells is a key issue in intelligent NC program-ming. On the basis of the NC machining craft of ASP, the paper aims to make an in-depth research on this issue. Firstly, some new terms about the residual volume and the machinable volume are defined, and then, the technological process is modeled with a process scheme. Secondly, the approach to building the machining cells is introduced, in which real-time complement machining is mainly considered to avoid interference and overcutting. Thirdly, the implementing algorithm is designed and applied to the Intelligent NC Programming System of ASP. Finally, the developed algorithm is validated through two case studies.

  12. Long ncRNA expression associates with tissue-specific enhancers.

    Science.gov (United States)

    Vučićević, Dubravka; Corradin, Olivia; Ntini, Evgenia; Scacheri, Peter C; Ørom, Ulf Andersson

    2015-01-01

    Long non-coding RNAs (ncRNA) have recently been demonstrated to be expressed from a subset of enhancers and to be required for the distant regulation of gene expression. Several approaches to predict enhancers have been developed based on various chromatin marks and occupancy of enhancer-binding proteins. Despite the rapid advances in the field, no consensus how to define tissue specific enhancers yet exists. Here, we identify 2,695 long ncRNAs annotated by ENCODE (corresponding to 28% of all ENCODE annotated long ncRNAs) that overlap tissue-specific enhancers. We use a recently developed algorithm to predict tissue-specific enhancers, PreSTIGE, that is based on the H3K4me1 mark and tissue specific expression of mRNAs. The expression of the long ncRNAs overlapping enhancers is significantly higher when the enhancer is predicted as active in a specific cell line, suggesting a general interdependency of active enhancers and expression of long ncRNAs. This dependency is not identified using previous enhancer prediction algorithms that do not account for expression of their downstream targets. The predicted enhancers that overlap annotated long ncRNAs generally have a lower ratio of H3K4me1 to H3K4me3, suggesting that enhancers expressing long ncRNAs might be associated with specific epigenetic marks. In conclusion, we demonstrate the tissue-specific predictive power of PreSTIGE and provide evidence for thousands of long ncRNAs that are expressed from active tissue-specific enhancers, suggesting a particularly important functional relationship between long ncRNAs and enhancer activity in determining tissue-specific gene expression.

  13. Directly Generating the NC Machining Program from AutoCAD Graph

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    One kind of auto-programming method directly gener at ing the NC machining program by AutoCAD graph is discussed in this article. Firs tly, the article discusses the open type graphic interface of AutoCAD. Then the graphic export among the AutoCAD, the adding of process information and the data storage, as well as technology of generating NC program has been introduced . Finally, a NC auto-programming system GAPS based on AutoCAD graph is develope d. The tendency of auto-programming is graphic auto-pro...

  14. The total nucleon-nucleon cross section at large N_c

    CERN Document Server

    Cohen, Thomas D

    2012-01-01

    It is shown that at sufficiently large $N_c$ for incident momenta which are much larger than the QCD, the total nucleon-nucleon cross section is independent of incident momentum and given by $\\sigma^{\\rm total}=2 \\pi \\log^2(N_c) / (m^2_{\\pi})$. This result is valid in the extreme large $N_c$ regime of $\\log(N_c) \\gg 1$ and has corrections of relative order $\\log (\\log(N_c))/\\log(N_c)$. A possible connection of this result to the Froissart-Martin bound is discussed.

  15. The origin of blue photoluminescence from nc-Si/SiO2 multilayers

    Institute of Scientific and Technical Information of China (English)

    Ma Zhong-Yuan; Xu Ling; Huang Xin-Fan; Chen Kun-Ji; Feng Duan; Guo Si-Hua; Chen De-Yuan; Wei De-Yuan; Yao Yao; Zhou Jiang; Huang Rui; Li Wei; Xu Jun

    2008-01-01

    Intensive blue photoluminescence (PL) was observed at room temperature from the nanocrystalline-Si/SiO2 (ncSi/SiO2) multilayers (MLs) obtained by thermal annealing of SiO/SiO2 MLs for the first time.By controlling the size of nc-Si formed in SiO sublayer from 3.5 to 1.5 nm,the PL peak blueshifts from 457 to 411 nm.Combining the analysis of TEM,Raman and absorption measurement,this paper attributes the blue PL to multiple luminescent centres at the interface of nc-Si and SiO2.

  16. Curie Transition of NC Nickel by Mechanical Spectroscopy and Magnetization Study

    Institute of Scientific and Technical Information of China (English)

    LI Ping-Yun; CAO Zhen-Hua; ZHANG Xi-Yan; WU Xiao-Lei; HUANG Yi-Neng; MENG Xiang-Kang

    2009-01-01

    Mechanical spectroscopy measurement is performed to study the internal friction of nanocrystalline (NC) nickel with an average grain size of 23 nm from room temperature to 610 K.An internal friction peak is observed at about 550 K,which corresponds to the Curie transition process of the NC nickel according to the result of magnetization test.Moreover,the fact that the Curie temperature of NC nickel is lower than that of coarse-grained nickel is explained by an analytical model based on the weakening of cohesive energy.

  17. Preparation and characterization of polymer blends of NC and GAP-TPE%NC/GAP-TPE共混聚合物的制备和性能研究

    Institute of Scientific and Technical Information of China (English)

    左海丽; 肖乐勤; 菅晓霞; 周伟良

    2011-01-01

    A series of blends of energetic thermoplastic polyurethane( GAP-TPE)and Nitrocellulose( NC) were prepared by the way of chain extension,blend and aging. The structures of the blends were analyzed by means of FT1R spectroscopy, wide-angle Xray diffraction,and scanning electron microscopy. The compatibility and properties of the blends were characterized by dynamic mechanical analysis( DMA)and tensile testing. It suggests that nitrocellulose molecules penetrate into the polyurethane and interrupt the intra-hydrogen bonding between the hard and soft segments. The results indicate that the blended sheets exhibited good miscibility. The tensile strength increased with an increase of NC content. The blends NC/GAP-TPE having 5%~20% NC exhibited a significant increase from 10.4 Mpa to 20.4 Mpa for tensile strength ,49% increased.%采用扩链后共混再熟化的方法,制备了1组不同组成的硝化棉(NC)/含能热塑性弹性体(GAP-TPE)共混聚合物.采用红外光谱(FTIR)和X射线衍射(XRD)表征NC/GAP-TPE共混物的结构,扫描电镜(SEM)观察共混物的断面,动态热机械分析(DMA)测定共混物的玻璃化转变,运用拉伸实验研究不同配比NC/GAP-TPE共混物的力学性能.结果表明,NC和GAP-TPE分子间存在氢键相互作用.NC均匀分散在GAP-TPE基体中,不同配比的NC/GAP-TPE共混物均存在1个玻璃化温度,二者之间具有较好的相容性.当NC含量从5%到20%变化时,共混试样的拉伸强度从10.4 MPa增加至20.4 MPa,提高了49%.

  18. First ITER Council convened in Cadarache - historic step in the quest for clean Energy 28 November 2007 Cadarache

    CERN Multimedia

    Hay, Jennifer

    2007-01-01

    "On 27 November 2007, the ITER Council convened for the first time in the history of the new International Organization. Opening the meeting, Dr Werner Burkart, Deputy Director of the International Atomic Energy Agency (AIEA), said: "Let me congratulate all who have contributed to the achievements of the ITER initiative to date.... (1,5 page)

  19. MACHINING OPTIMISATION AND OPERATION ALLOCATION FOR NC LATHE MACHINES IN A JOB SHOP MANUFACTURING SYSTEM

    Directory of Open Access Journals (Sweden)

    MUSSA I. MGWATU

    2013-08-01

    Full Text Available Numerical control (NC machines in a job shop may not be cost and time effective if the assignment of cutting operations and optimisation of machining parameters are overlooked. In order to justify better utilisation and higher productivity of invested NC machine tools, it is necessary to determine the optimum machining parameters and realize effective assignment of cutting operations on machines. This paper presents two mathematical models for optimising machining parameters and effectively allocating turning operations on NC lathe machines in a job shop manufacturing system. The models are developed as non-linear programming problems and solved using a commercial LINGO software package. The results show that the decisions of machining optimisation and operation allocation on NC lathe machines can be simultaneously made while minimising both production cost and cycle time. In addition, the results indicate that production cost and cycle time can be minimised while significantly reducing or totally eliminating idle times among machines.

  20. Fabrication and characteristics of the nc-Si/c-Si heterojunction MAGFET

    Institute of Scientific and Technical Information of China (English)

    Zhao Xiaofeng; Wen Dianzhong

    2009-01-01

    A MAGFET using an nc-Si/c-Si heterojunction as source and drain was fabricated by CMOS technology, using two ohm-contact electrodes as Hall outputs on double sides of the channel situated 0.7L from the source. The experimental results show that when V_(DS) = -7.0 V, the magnetic sensitivity of the single nc-Si/c-Si heterojunction magnetic metal oxide semiconductor field effect transistor (MAGFET) with an L : W ratio of 2 : 1 is 21.26 mV/T,and that with an L : W ratio of 4 : 1 is 13.88 mV/T. When the outputs of double nc-Si/c-Si heterojunction MAGFETs with an L : W ratio of 4 : 1 are in series, their magnetic sensitivity is 22.74 mV/T, which is an improvement of about 64% compared with that of a single nc-Si/c-Si heterojunction MAGFET.

  1. Investigation on the foaming behaviors of NC-based gun propellants

    Directory of Open Access Journals (Sweden)

    Yu-xiang Li

    2014-09-01

    Full Text Available To prepare the porous NC-based (nitrocellulose-based gun propellants, the batch foaming process of using supercritical CO2 as the physical blowing agent is used. The solubilities of CO2 in the single-base propellants and TEGDN (trimethyleneglycol dinitrate propellants are measured by the gravimetric method, and SEM (scanning electron microscope is used to observe the morphology of foamed propellants. The result shows that a large amount of CO2 could be dissolved in NC-based propellants. The experimental results also reveal that the energetic plasticizer TEGDN exerts an important influence on the pore structure. The triaxial tensile failure mechanism for solid-state nucleation is used to explain the nucleation of NC-based propellants in the solid state. Since some specific foaming behaviors of NC-based propellants can not be explained by the failure mechanism, a solid-state nucleation mechanism which revises the triaxial tensile failure mechanism is proposed and discussed.

  2. EnviroAtlas -Durham, NC- One Meter Resolution Urban Area Land Cover Map (2010)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EnviroAtlas Durham, NC land cover map was generated from USDA NAIP (National Agricultural Imagery Program) four band (red, green, blue and near infrared) aerial...

  3. EnviroAtlas -Durham, NC- One Meter Resolution Urban Area Land Cover Map (2010) Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas web service supports research and online mapping activities related to EnviroAtlas (https://www.epa.gov/enviroatlas ). The EnviroAtlas Durham, NC...

  4. THE ROLE OF STEP-NC IN IMPROVING THE PERFORMANCE OF SUPPLY CHAIN

    Directory of Open Access Journals (Sweden)

    The Jaya Suteja

    2005-01-01

    Full Text Available The success of supply chain implementation in producing manufactured product heavily relies on the development of CAD system, CAM system, and CNC machine tool. However, current CAD system, CAM system, and CNC machine tool have some weaknesses in supporting supply chain implementation. This paper presents an overview of STEP-NC and its role in supply chain of manufactured product. STEP-NC is a new interface standard for CAD-CAM-CNC chain, which is developed by International Standards Organization (ISO to extend STEP model data to define data for NC machine tools. By using STEP-NC, the link of all information in supply chain of manufactured product will be more flexible, faster, easier, safer, and more reliable.

  5. Complete Genome Sequence of NC983, a Live Attenuated Strain of Salmonella enterica Serovar Typhimurium

    Science.gov (United States)

    Troxell, Bryan; Fink, Ryan C.; Dickey, Allison N.; Scholl, Elizabeth H.

    2016-01-01

    Foodborne infections caused by Salmonella enterica serovars are a significant problem worldwide. Presented here is the genome sequence of the nontyphoidal S. enterica serovar Typhimurium mutant strain NC983, a potential vaccine candidate. PMID:27738027

  6. Evolution of twist-three parton distributions in QCD beyond the large $N_{c}$ limit

    CERN Document Server

    Braun, V M; Manashov, A N

    2000-01-01

    We formulate a consistent 1/N_c^2 expansion of the QCD evolution equations for the twist-three quark distributions g_2(x,Q^2), h_L(x,Q^2) and e(x,Q^2) based on the interpretation of the evolution as a three-particle quantum-mechanical problem with hermitian Hamiltonian. Each distribution amplitude can be decomposed in contributions of partonic components with DGLAP-type scale dependence. We calculate the 1/N_c^2 corrections to the evolution of the dominant component with the lowest anomalous dimension - the only one that survives in the large-N_c limit - and observe a good agreement with the exact numerical results for N_c=3. The 1/N_c^2 admixture of operators with higher anomalous dimensions is shown to be concentrated at a few lowest partonic components and in general is rather weak.

  7. 75 FR 71463 - Woodland Mills Corporation Mill Spring, NC; Notice of Revised Determination on Reconsideration

    Science.gov (United States)

    2010-11-23

    ... Employment and Training Administration Woodland Mills Corporation Mill Spring, NC; Notice of Revised... of Woodland Mills Corporation, Mill Spring, North Carolina, to apply for Trade Adjustment Assistance... yarn produced by Woodland Mills Corporation, Mill Spring, North Carolina Woodland Mills...

  8. 75 FR 49524 - Woodland Mills Corporation, Mill Spring, NC; Notice of Affirmative Determination Regarding...

    Science.gov (United States)

    2010-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Woodland Mills Corporation, Mill Spring, NC; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated July 22, 2010,...

  9. SIMULATION SYSTEM FOR FIVE-AXIS NC MACHINING USING GENERAL CUTTING TOOL

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A simulation system for five-axis NC machining using general cutting tools is presented. This system differs from other simulation system in that it not only focuses on the geometric simulation but also focuses on the collision detection which is usually not included in NC machining simulation. Besides all of these, estimating cutting forces is also discussed. In order to obtain high efficiency, all algorithms use swept volume modeling technique, so the simulation system is compact and can be performed efficiently.

  10. Removal of aqueous nC60 fullerene from water by low pressure membrane filtration.

    Science.gov (United States)

    Floris, R; Nijmeijer, K; Cornelissen, E R

    2016-03-15

    The potential environmental and health risks of engineered nanoparticles such as buckminsterfullerene C60 in water require their removal during the production of drinking water. We present a study focusing on (i) the removal mechanism and (ii) the elucidation of the role of the membrane pore size during removal of nC60 fullerene nanoparticle suspensions in dead-end microfiltration and ultrafiltration mimicking separation in real industrial water treatment plants. Membranes were selected with pore sizes ranging from 18 nm to 500 nm to determine the significance of the nC60 to membrane pore size ratio and the adsorption affinity between nC60 and membrane material during filtration. Experiments were carried out with a dead-end bench-scale system operated at constant flux conditions including a hydraulic backwash cleaning procedure. nC60 nanoparticles can be efficiently removed by low pressure membrane technology with smaller and, unexpectedly, also by mostly similar or larger pores than the particle size, although the nC60 filtration behaviour appeared to be different. The nC60 size to membrane pore size ratio and the ratio of the cake-layer deposition resistance to the clean membrane resistance, both play an important role on the nC60 filtration behaviour and on the efficiency of the backwash procedure recovering the initial membrane filtration conditions. These results become specifically significant in the context of drinking water production, for which they provide relevant information for an accurate selection between membrane processes and operational parameters for the removal of nC60 in the drinking water treatment.

  11. A novel denitrifying methanotroph of the NC10 phylum and its microcolony

    Science.gov (United States)

    He, Zhanfei; Cai, Chaoyang; Wang, Jiaqi; Xu, Xinhua; Zheng, Ping; Jetten, Mike S. M.; Hu, Baolan

    2016-09-01

    The NC10 phylum is a candidate phylum of prokaryotes and is considered important in biogeochemical cycles and evolutionary history. NC10 members are as-yet-uncultured and are difficult to enrich, and our knowledge regarding this phylum is largely limited to the first species ‘Candidatus Methylomirabilis oxyfera’ (M. oxyfera). Here, we enriched NC10 members from paddy soil and obtained a novel species of the NC10 phylum that mediates the anaerobic oxidation of methane (AOM) coupled to nitrite reduction. By comparing the new 16S rRNA gene sequences with those already in the database, this new species was found to be widely distributed in various habitats in China. Therefore, we tentatively named it ‘Candidatus Methylomirabilis sinica’ (M. sinica). Cells of M. sinica are roughly coccus-shaped (0.7–1.2 μm), distinct from M. oxyfera (rod-shaped; 0.25–0.5 × 0.8–1.1 μm). Notably, microscopic inspections revealed that M. sinica grew in honeycomb-shaped microcolonies, which was the first discovery of microcolony of the NC10 phylum. This finding opens the possibility to isolate NC10 members using microcolony-dependent isolation strategies.

  12. The baryon vector current in the combined chiral and 1/Nc expansions

    Energy Technology Data Exchange (ETDEWEB)

    Flores-Mendieta, Ruben; Goity, Jose L [JLAB

    2014-12-01

    The baryon vector current is computed at one-loop order in large-Nc baryon chiral perturbation theory, where Nc is the number of colors. Loop graphs with octet and decuplet intermediate states are systematically incorporated into the analysis and the effects of the decuplet-octet mass difference and SU(3) flavor symmetry breaking are accounted for. There are large-Nc cancellations between different one-loop graphs as a consequence of the large-Nc spin-flavor symmetry of QCD baryons. The results are compared against the available experimental data through several fits in order to extract information about the unknown parameters. The large-Nc baryon chiral perturbation theory predictions are in very good agreement both with the expectations from the 1/Nc expansion and with the experimental data. The effect of SU(3) flavor symmetry breaking for the |Delta S|=1 vector current form factors f1(0) results in a reduction by a few percent with respect to the corresponding SU(3) symmetric values.

  13. Comparative Analysis on the Evaluating Indicators of Building Energy Efficiency in LEED-NC4.0 and LEED-NC2009%LEED-NC4.0与LEED-NC2009建筑节能评价指标对比研究

    Institute of Scientific and Technical Information of China (English)

    周同; 刘丛红

    2014-01-01

    LEED-NC是美国建筑绿色评价体系,适用于新建建筑和旧建筑重大改造项目。以该体系中建筑节能评价指标为研究对象,在建立LEED-NC4.0版本和LEED-NC2009版本相关评价指标对应关系的基础上,对新旧版本中建筑节能评价指标进行了对比分析,总结LEED-NC4.0在建筑节能评价方面的变化,包括进一步降低建筑的运行能耗、加强性能计量、注重系统调试、鼓励智能电网计数的应用,并对LEED-NC建筑节能评价指标的发展趋势进行了分析。通过分析,加深对LEED-NC建筑节能评价的理解,为我国绿色建筑评价标准的发展提供借鉴。%LEED-NC is a U.S. green building rating system applying for new construction and major renovation. Taking the evaluating indicators of building energy efficiency as objective of study, the paper develops the correspondence between energy saving relative indicators in new and old versions of LEED-NC. Main changes of LEED-NC4.0 on building energy efficiency are summarized through the comparative analysis on the evaluating indicators in LEED-NC2009 and LEED-NC4.0, including reducing building op-eration energy use, strengthening performance metering, emphasizing system commissioning and encourag-ing use of the smart grid. It can deepen the understanding of LEED-NC and provides reference meaning to our green building assessment criteria development.

  14. Polarized photoluminescence of nc-Si–SiO{sub x} nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Michailovska, E. V.; Indutnyi, I. Z.; Shepeliavyi, P. E.; Sopinskii, N. V., E-mail: sopinsky@isp.kiev.ua, E-mail: sopinskyy@ua.fm [National Academy of Sciences of Ukraine, Lashkarev Institute of Semiconductor Physics (Ukraine)

    2016-01-15

    The effect of photoluminescence polarization memory in nc-Si–SiO{sub x} light-emitting structures containing Si nanoparticles (nc-Si) in an oxide matrix is for the first time studied. The polarization properties of continuous and porous nanostructures passivated in HF vapors (or solutions) are studied. It is established that the polarization memory effect is manifested only after treatment of the structures in HF. The effect is also accompanied by a shift of the photoluminescence peak to shorter wavelengths and by a substantial increase in the photoluminescence intensity. It is found that, in anisotropic nc-Si–SiO{sub x} samples produced by oblique deposition in vacuum, the degree of linear photoluminescence polarization in the sample plane exhibits a noticeable orientation dependence and correlates with the orientation of SiO{sub x} nanocolumns forming the structure of the porous layer. These effects are attributed to the transformation of symmetrically shaped Si nanoparticles into asymmetric elongated nc-Si particles upon etching in HF. In continuous layers, nc-Si particles are oriented randomly, whereas in porous structures, their preferential orientation coincides with the orientation of oxide nanocolumns.

  15. Link between the Potentially Hazardous Asteroid (86039) 1999 NC43 and the Chelyabinsk meteoroid tenuous

    CERN Document Server

    Reddy, Vishnu; Bottke, William F; Pravec, Petr; Sanchez, Juan A; Gary, Bruce L; Klima, Rachel; Cloutis, Edward A; Galád, Adrián; Guan, Tan Thiam; Hornoch, Kamil; Izawa, Matthew R M; Kušnirák, Peter; Corre, Lucille Le; Mann, Paul; Moskovitz, Nicholas; Skiff, Brian; Vraštil, Jan

    2015-01-01

    We explored the statistical and compositional link between Chelyabinsk meteoroid and potentially hazardous asteroid (86039) 1999 NC43 to investigate their proposed relation proposed by Borovi\\v{c}ka et al. (2013). Using detailed computation we confirm that the orbit of the Chelyabinsk impactor is anomalously close to 1999 NC43. We find about (1-3) x 10-4 likelihood of that to happen by chance. Taking the standpoint that the Chelyabinsk impactor indeed separated from 1999 NC43 by a cratering or rotational fission event, we run a forward probability calculation, which is an independent statistical test. However, we find this scenario is unlikely at the about (10-3 -10-2) level. We also verified compositional link between Chelyabinska and 1999NC43. Mineralogical analysis of Chelyabinsk (LL chondrite) and (8) Flora (the largest member of the presumed LL chondrite parent family) shows that their olivine and pyroxene chemistries are similar to LL chondrites. Similar analysis of 1999 NC43 shows that its olivine and ...

  16. Thin-walled aluminum alloy tube NC precision bending based on finite element simulation

    Institute of Scientific and Technical Information of China (English)

    GU Rui-jie; YANG He; ZHAN Mei; LI Heng

    2006-01-01

    Elongation and springback are the bottleneck problems of thin-walled aluminum alloy tube NC precision bending. So thin-walled aluminum alloy tube NC precision bending based on finite element simulation is put forward. The finite element model of thin-walled aluminum alloy tube NC bending is established based on the DYNAFORM platform. The process of thin-walled aluminum alloy tube NC precision bending is simulated with the model and the elongation and springback of tube bending can be is put forward and the computing equations of bending angle, bending radius, blanking length and initial bending section based on elongation and springback angle are derived. The bending angle, bending radius, blanking length and initial bending section of tube bending can be gained with these equations based on the elongation and springback angle from the simulation. The study can be used to control the quality of thin-walled aluminum alloy tube NC bending so that precision bending without redundance can be realized.

  17. Polarization memory effect in the photoluminescence of nc-Si-SiOx light-emitting structures

    Science.gov (United States)

    Michailovska, Katerina; Indutnyi, Ivan; Shepeliavyi, Petro; Sopinskyy, Mykola

    2016-06-01

    The polarization memory (PM) effect in the photoluminescence (PL) of the porous nc-Si-SiOx light-emitting structures, containing nanoparticles of silicon (nc-Si) in the oxide matrix and passivated in a solution of hydrofluoric acid (HF), has been investigated. The studied nc-Si-SiOx structures were produced by evaporation of Si monoxide (SiO) powder in vacuum and oblique deposition on Si wafer, and then the deposited silicon oxide (SiOx) films were annealed in the vacuum at 975 °C to grow nc-Si. It was found that the PM effect in the PL is observed only after passivation of nanostructures: during etching in HF solution, the initial symmetric nc-Si becomes asymmetric elongated. It was also found that in investigated nanostructures, there is a defined orientational dependence of the PL polarization degree ( ρ) in the sample plane which correlates with the orientation of SiOx nanocolumns, forming the structure of the porous layer. The increase of the ρ values in the long-wavelength spectral range with time of HF treatment can be associated with increasing of the anisotropy of large Si nanoparticles. The PM effect for this spectral interval can be described by the dielectric model. In the short-wavelength spectral range, the dependence of the ρ values agrees qualitatively with the quantum confinement effect.

  18. Baryons and baryonic matter in the large Nc and heavy quark limits

    CERN Document Server

    Cohen, Thomas D; Ndousse, Kamal K

    2011-01-01

    This paper explores properties of baryons and finite density baryonic matter in an artificial world in which Nc, the number of colors, is large and the quarks of all species are degenerate and much larger than {\\Lambda}_QCD. It has long been known that in large Nc QCD, baryons composed entirely of heavy quarks are accurately described in the mean-field approximation. However, the detailed properties of baryons in the combined large Nc and heavy quark limits have not been fully explored. Here some basic properties of baryons are computed using a variational approach. At leading order in both the large Nc and heavy quark expansions the baryon mass is computed explicitly as is the baryon form factor. Baryonic matter, the analog of nuclear matter in this artificial world, should also be well described in the mean-field approximation. In the special case where all baryons have an identical spin flavor structure, it is shown that in the formal heavy quark and large Nc limit interactions between baryons are strictly...

  19. Polarization memory effect in the photoluminescence of nc-Si-SiOx light-emitting structures.

    Science.gov (United States)

    Michailovska, Katerina; Indutnyi, Ivan; Shepeliavyi, Petro; Sopinskyy, Mykola

    2016-12-01

    The polarization memory (PM) effect in the photoluminescence (PL) of the porous nc-Si-SiOx light-emitting structures, containing nanoparticles of silicon (nc-Si) in the oxide matrix and passivated in a solution of hydrofluoric acid (HF), has been investigated. The studied nc-Si-SiOx structures were produced by evaporation of Si monoxide (SiO) powder in vacuum and oblique deposition on Si wafer, and then the deposited silicon oxide (SiOx) films were annealed in the vacuum at 975 °C to grow nc-Si. It was found that the PM effect in the PL is observed only after passivation of nanostructures: during etching in HF solution, the initial symmetric nc-Si becomes asymmetric elongated. It was also found that in investigated nanostructures, there is a defined orientational dependence of the PL polarization degree (ρ) in the sample plane which correlates with the orientation of SiOx nanocolumns, forming the structure of the porous layer. The increase of the ρ values in the long-wavelength spectral range with time of HF treatment can be associated with increasing of the anisotropy of large Si nanoparticles. The PM effect for this spectral interval can be described by the dielectric model. In the short-wavelength spectral range, the dependence of the ρ values agrees qualitatively with the quantum confinement effect.

  20. Noise in NC-AFM measurements with significant tip–sample interaction

    Science.gov (United States)

    Lübbe, Jannis; Temmen, Matthias

    2016-01-01

    Summary The frequency shift noise in non-contact atomic force microscopy (NC-AFM) imaging and spectroscopy consists of thermal noise and detection system noise with an additional contribution from amplitude noise if there are significant tip–sample interactions. The total noise power spectral density D Δ f(f m) is, however, not just the sum of these noise contributions. Instead its magnitude and spectral characteristics are determined by the strongly non-linear tip–sample interaction, by the coupling between the amplitude and tip–sample distance control loops of the NC-AFM system as well as by the characteristics of the phase locked loop (PLL) detector used for frequency demodulation. Here, we measure D Δ f(f m) for various NC-AFM parameter settings representing realistic measurement conditions and compare experimental data to simulations based on a model of the NC-AFM system that includes the tip–sample interaction. The good agreement between predicted and measured noise spectra confirms that the model covers the relevant noise contributions and interactions. Results yield a general understanding of noise generation and propagation in the NC-AFM and provide a quantitative prediction of noise for given experimental parameters. We derive strategies for noise-optimised imaging and spectroscopy and outline a full optimisation procedure for the instrumentation and control loops.

  1. Nuclear Quadrupole Hyperfine Structure in HC14N/H14NC and DC15N/D15NC Isomerization: A Diagnostic Tool for Characterizing Vibrational Localization

    CERN Document Server

    Wong, Bryan M

    2010-01-01

    Large-amplitude molecular motions which occur during isomerization can cause significant changes in electronic structure. These variations in electronic properties can be used to identify vibrationally-excited eigenstates which are localized along the potential energy surface. This work demonstrates that nuclear quadrupole hyperfine interactions can be used as a diagnostic marker of progress along the isomerization path in both the HC14N/H14NC and DC15N/D15NC chemical systems. Ab initio calculations at the CCSD(T)/cc-pCVQZ level indicate that the hyperfine interaction is extremely sensitive to the chemical bonding of the quadrupolar 14N nucleus and can therefore be used to determine in which potential well the vibrational wavefunction is localized. A natural bonding orbital analysis along the isomerization path further demonstrates that hyperfine interactions arise from the asphericity of the electron density at the quadrupolar nucleus. Using the CCSD(T) potential surface, the quadrupole coupling constants of...

  2. Multi-agent System for Process Planning in Step-nc Based Manufacturing

    Directory of Open Access Journals (Sweden)

    Juan Du

    2012-09-01

    Full Text Available In order to realize STEP-NC-oriented computer numerical control machining and achieve optimal performance in manufacturing, a multi-agent system for process planning in STEP-NC based manufacturing was designed. By analyzing the characteristic of STEP-NC data model, a manufacturing feature-oriented process planning method was proposed in this study and the distributed artificial intelligence methods, namely collaborative multi-agent was employed to accomplish process planning of part. The proposed multi-agent system consists of three types of autonomous agents, which are global manager agents, planning agents and manufacturing resource agents, respectively. Process planning can be automatically completed by multiple agents’ cooperation. Each agent is capable of communicating to each other through improved Knowledge Query and Manipulation Language (KQML. At last, one test part was designed and simulated to demonstrate the capabilities of this research in the study.

  3. Non-convex prior image constrained compressed sensing (NC-PICCS)

    Science.gov (United States)

    Ramírez Giraldo, Juan Carlos; Trzasko, Joshua D.; Leng, Shuai; McCollough, Cynthia H.; Manduca, Armando

    2010-04-01

    The purpose of this paper is to present a new image reconstruction algorithm for dynamic data, termed non-convex prior image constrained compressed sensing (NC-PICCS). It generalizes the prior image constrained compressed sensing (PICCS) algorithm with the use of non-convex priors. Here, we concentrate on perfusion studies using computed tomography examples in simulated phantoms (with and without added noise) and in vivo data, to show how the NC-PICCS method holds potential for dramatic reductions in radiation dose for time-resolved CT imaging. We show that NC-PICCS can provide additional undersampling compared to conventional convex compressed sensing and PICCS, as well as, faster convergence under a quasi-Newton numerical solver.

  4. Large Nc deconfinement transition in the presence of a magnetic field

    Science.gov (United States)

    Fraga, Eduardo S.; Noronha, Jorge; Palhares, Letícia F.

    2013-06-01

    We investigate the effect of a homogeneous magnetic field on the thermal deconfinement transition of QCD in the large Nc limit. First we discuss how the critical temperature decreases due to the inclusion of Nf≪Nc flavors of massless quarks in comparison to the pure glue case. Then we study the equivalent correction in the presence of an external Abelian magnetic field. To leading order in Nf/Nc, the deconfinement critical temperature decreases with the magnetic field if the flavor contribution to the pressure behaves paramagnetically, with a sufficiently large magnetization as to overcome any possible magnetic effects in the string tension. Finally, we discuss the effects from a finite quark mass and its competition with magnetic effects.

  5. The NC Power Supply Design of Large Current and Wide Frequency Pulse in SEAM

    Directory of Open Access Journals (Sweden)

    Jianping Zhou

    2013-07-01

    Full Text Available There are a lot of ways to achieve large current pulse power supply, and the more common way is to adopt the inverter switching circuit to achieve pulse power supply. The core of the NC power supply design of large current and wide frequency pulse in SEAM is using two-stage modulation. Combined with inverter technology, DC chopper technology and NC technology, it not only can achieve the adjustability of the output pulse amplitude, but also can realize continuous adjustment of the output pulses and the duty cycle. The front stage of power supply uses DC/DC transformation circuit with the UC3879 integrated control chip as the core. With the microcontroller as the control core, the backward stage uses DC chopper circuit to achieve the NC power supply of multi-parameter adjustable output large current pulse.

  6. NC INCREMENTAL SHEET METAL FORMING PROCESS AND VERTICAL WALL SQUARE BOX FORMING

    Institute of Scientific and Technical Information of China (English)

    Zhou Liuru; Mo Jianhua; Xiao Xiangzhi

    2004-01-01

    The forming principle and deformation analysis of NC incremental sheet metal forming process as well as the process planning, experiment and key process parameters of vertical wall square box forming are presented. Because the deformation of sheet metal only occurs around the tool head and the deformed region is subjected to stretch deformation, the deformed region of sheet metal thins, and surface area increases. Sheet metal forming stepwise is to lead to the whole sheet metal deformation. The forming half-apex angle θ and corner radius R are the main process parameters in NC incremental forming of vertical wall square box. According to sine law, a vertical wall square box can't be formed by NC incremental sheet metal forming process in a single process, rather, it must be formed in multi processes. Thus, the parallel line type tool path process method is presented to form the vertical wall square box, and the experiment and analysis are made to verify it.

  7. Max-Flow Problem in Undirected Planar Networks with Node Capacities Being in NC

    Institute of Scientific and Technical Information of China (English)

    Xian-Chao Zhang; Ying-Yu Wan; Guo-Liang Chen

    2004-01-01

    The max-flow problem in planar networks with only edge capacities has been proved to be in NC (Nickle's Class). This paper considers a more general version of the problem when the nodes as well as the edges have capacities. In a general network, the node-edge-capacity problem can be easily reduced to the edge-capacity problem. But in the case of planar network this reduction may destroy the planarity, and reduces the problem to the edge-capacity problem in a general network, which is P-complete. A recent contribution presents a new reduction for planar networks, that maintains the planarity. In this paper, it is proved that this reduction is in NC and thus the node-edge-capacity problem in undirected planar networks is in NC.

  8. Role of the NC-loop in catalytic activity and stability in lipase from Fervidobacterium changbaicum.

    Directory of Open Access Journals (Sweden)

    Binchun Li

    Full Text Available Flexible NC-loops between the catalytic domain and the cap domain of the α/β hydrolase fold enzymes show remarkable diversity in length, sequence, and configuration. Recent investigations have suggested that the NC-loop might be involved in catalysis and substrate recognition in many enzymes from the α/β hydrolase fold superfamily. To foster a deep understanding of its role in catalysis, stability, and divergent evolution, we here systemically investigated the function of the NC-loop (residues 131-151 in a lipase (FClip1 from thermophilic bacterium Fervidobacterium changbaicum by loop deletion, alanine-scanning mutagenesis and site-directed mutagenesis. We found that the upper part of the NC-loop (residues 131-138 was of great importance to enzyme catalysis. Single substitutions in this region could fine-tune the activity of FClip1 as much as 41-fold, and any deletions from this region rendered the enzyme completely inactive. The lower part of the NC-loop (residues 139-151 was capable of enduring extensive deletions without loss of activity. The shortened mutants in this region were found to show both improved activity and increased stability simultaneously. We therefore speculated that the NC-loop, especially the lower part, would be a perfect target for enzyme engineering to optimize the enzymatic properties, and might present a hot zone for the divergent evolution of α/β hydrolases. Our findings may provide an opportunity for better understanding of the mechanism of divergent evolution in the α/β hydrolase fold superfamily, and may also guide the design of novel biocatalysts for industrial applications.

  9. Tricolor microcavity OLEDs based on P-nc-Si:H films as the complex anodes

    Institute of Scientific and Technical Information of China (English)

    Li Yang; Liu Xingyuan; Wu Chunya; Meng Zhiguo; Wang Yi; Xiong Shaozhen

    2009-01-01

    A P+-nc-Si:H film (boron-doped nc-Si:H thin film) was used as a complex anode of an OLED. As an ideal candidate for the composite anode, the P+-nc-Si:H thin film has a good conductivity with a high work function (~5.7 eV) and outstanding optical properties of high reflectivity, transmission, and a very low absorption. As a result, the combination of the relatively high reflectivity of a P+-nc-Si:H film/ITO complex anode with the very high reflectivity of an Al cathode could form a micro-cavity structure with a certain Q to improve the efficiency of the OLED fabricated on it. An RGB pixel generated by microcavity OLEDs is beneficial for both the reduction of the light loss and the improvement of the color purity and the efficiency. The small molecule Alq would be useful for the emitting light layer (EML) of the MOLED, and the P+-nc-Si film would be used as a complex anode of the MOLED, whose configuration can be constructed as Glass/LTO/P+-nc-Si:H/ITO/MoO3/NPB/Alq/LiF/Al. By adjusting the thickness of the organic layer NPB/Alq, the optical length of the microcavity and the REB colors of the device can be obtained. The peak wavelengths of an OLED are located at 486, 550, and 608 nm, respectively.The CIE coordinates are (0.21,0.45), (0.33,0.63), and (0.54,0.54), and the full widths at half maximum (FWHM)are 35, 32, and 39 nm for red, green, and blue, respectively.

  10. NC plane waves, Casimir effect and flux tube potential with L\\"uscher terms

    CERN Document Server

    Kováčik, Samuel

    2016-01-01

    We analyze plane waves in a model of quantum mechanics in a three dimensional noncommutative (NC) space $R^3_{\\lambda}$. Signature features of NC models are impossibility of probing distances smaller than a certain length scale {\\lambda} and a presence of natural energetic cut-off at energy scale of order $1/{\\lambda}^2$ (in convenient units). We analyze consequences of such restrictions on a 1 dimensional Casimir effect. The result shows resemblance to flux tube potential for quark-antiquark pairs and to effective bosonic string theories with L\\"uscher terms. Such behavior might effect the radius of possible compact (fuzzy) dimensions.

  11. A Search for Neutrino Induced Coherent NC($\\pi^{0}$) Production in the MINOS Near Detector

    Energy Technology Data Exchange (ETDEWEB)

    Cherdack, Daniel David [Tufts Univ., Medford, MA (United States)

    2011-02-01

    The production of single, highly forward π0 mesons by NC coherent neutrino-nucleus interactions (νμ + N → νμ + N + π0) is a process which probes fundamental aspects of the weak interaction. This reaction may also pose as a limiting background for long baseline searches for νμ → νe oscillations if the neutrino mixing angle θ13 is very small. The high-statistics sample of neutrino interactions recorded by the MINOS Near Detector provides an opportunity to measure the cross section of this coherent reaction on a relatively large-A nucleus at an average Ev = 4.9 GeV. A major challenge for this measurement is the isolation of forward-going electromagnetic (EM) showers produced by the relatively rare coherent NC0) process amidst an abundant rate of incoherently produced EM showers. The backgrounds arise from single π0 dominated NC events and also from quasi-elastic-like CC scattering of electron neutrinos. In this Thesis the theory of coherent interactions is summarized, and previous measurements of the coherent NC0) cross section are reviewed. Then, methods for selecting a sample of coherent NC0) like events, extracting the coherent NC0) event rate from that sample, estimating the analysis uncertainties, and calculating a cross section, are presented. A signal for neutrino-induced NC0) production is observed in the relevant kinematic regime as an excess of events of three standard deviations above background. The reaction cross sections, averaged over an energy window of 2.5 ≤ Ev ≤ 9.0 GeV is determined to be (31.6±10.5) x 10-40 cm2/nucleus. The result is the first evidence obtained for neutrino-nucleus coherent NC0) scattering on iron, and is the first measurement on an average nuclear target above A = 30. The cross section measurement

  12. Large Nc Deconfinement Transition in the Presence of a Magnetic Field

    CERN Document Server

    Fraga, Eduardo S; Palhares, Leticia F

    2013-01-01

    We investigate the effect of a homogeneous magnetic field on the thermal deconfinement transition of QCD in the large $N_c$ limit. First we discuss how the critical temperature decreases due to the inclusion of $N_f \\ll N_c$ flavors of massless quarks. Then we study the equivalent correction in the presence of an external Abelian magnetic field. To leading order in $N_{f}/N_{c}$, the fact that the deconfinement critical temperature decreases with the magnetic field depends solely on quarks behaving paramagnetically. Finally, we discuss the effects from a finite quark mass and its competition with magnetic effects.

  13. Temperature variation of optical parameters in nc-CdSe thin films

    Science.gov (United States)

    Sharma, Kriti; Al-Kabbi, Alaa S.; Saini, G. S. S.; Tripathi, S. K.

    2012-06-01

    The nanocrystalline thin films of Cd30Se70 are prepared by thermal vaccum evaporation technique using Inert Gas Condensation method at room temperature. The transmission spectra are recorded using Monochromator-spectrograph [SOLAR TII, MS 2004] in the transmission range 400-850 nm for nc-CdSe thin films. Temperature dependence of energy gap (Eg), refractive index (n) for nc-CdSe thin films have been studied from 290 K to 370 K through the transmission spectra using Swanepoel method. It has been observed that energy gap decreases and refractive index increases with increase in temperature.

  14. Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins

    Directory of Open Access Journals (Sweden)

    Skogerbø Geir

    2008-06-01

    Full Text Available Abstract Background Short non-coding RNAs (ncRNAs perform their cellular functions in ribonucleoprotein (RNP complexes, which are also essential for maintaining the stability of the ncRNAs. Depletion of individual protein components of non-coding ribonucleoprotein (ncRNP particles by RNA interference (RNAi may therefore affect expression levels of the corresponding ncRNA, and depletion of candidate associated proteins may constitute an alternative strategy when investigating ncRNA-protein interactions and ncRNA functions. Therefore, we carried out a pilot study in which the effects of RNAi against protein components of small nucleolar RNPs (snoRNPs in Caenorhabditis elegans were observed on an ncRNA microarray. Results RNAi against individual C. elegans protein components of snoRNPs produced strongly reduced mRNA levels and distinct phenotypes for all targeted proteins. For each type of snoRNP, individual depletion of at least three of the four protein components produced significant (P ≦ 1.2 × 10-5 reductions in the expression levels of the corresponding small nucleolar RNAs (snoRNAs, whereas the expression levels of other ncRNAs were largely unaffected. The effects of depletion of individual proteins were in accordance with snoRNP structure analyses obtained in other species for all but two of the eight targeted proteins. Variations in snoRNA size, sequence and secondary structure characteristics were not systematically reflected in the affinity for individual protein component of snoRNPs. The data supported the classification of nearly all annotated snoRNAs and suggested the presence of several novel snoRNAs among unclassified short ncRNA transcripts. A number of transcripts containing canonical Sm binding element sequences (Sm Y RNAs also showed reduced expression after depletion of protein components of C/D box snoRNPs, whereas the expression of some stem-bulge RNAs (sbRNAs was increased after depletion of the same proteins. Conclusion

  15. Areva excellent business volume: backlog as of december 31, 2008: + 21.1% to 48.2 billion euros. 2008 revenue: + 10.4% to 13.2 billion euros; Areva excellent niveau d'activite: carnet de commandes au 31/12/2008: + 21,1% a 48,2 Mds d'euros. Chiffre d'affaires de l'exercice 2008: + 10,4% a 13,2 Mds d'euros

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    AREVA's backlog stood at 48.2 billion euros as of December 31, 2008, for 21.1% growth year-on-year, including 21.8% growth in Nuclear and 16.5% growth in Transmission and Distribution. The Nuclear backlog came to 42.5 billion euros at December 31, 2008. The Transmission and Distribution backlog came to 5.7 billion euros at year-end. The group recognized revenue of 13.2 billion euros in 2008, for year-on-year growth of 10.4% (+9.8% like-for-like). Revenue outside France was up 10.5% to 9.5 billion euros, representing 72% of total revenue. Revenue was up 6.5% in the Nuclear businesses (up 6.3% LFL), with strong performance in the Reactors and Services division (+10.9% LFL) and the Front End division (+7.2% LFL). The Transmission and Distribution division recorded growth of 17% (+15.8% LFL). Revenue for the fourth quarter of 2008 rose to 4.1 billion euros, up 5.2% (+1.6% LFL) from that of the fourth quarter of 2007. Revenue for the Front End division rose to 3.363 billion euros in 2008, up 7.1% over 2007 (+7.2% LFL). Foreign exchange (currency translations) had a negative impact of 53 million euros. Revenue for the Reactors and Services division rose to 3.037 billion euros, up 11.8% over 2007 (+10.9% LFL). Foreign exchange (currency translations) had a negative impact of 47 million euros. Revenue for the Back End division came to 1.692 billion euros, a drop of 2.7% (-2.5% LFL). Foreign exchange (currency translations) had a negative impact of 3.5 million euros. Revenue for the Transmission and Distribution division rose to 5.065 billion euros in 2008, up 17.0% (+15.8% LFL)

  16. Cloning and Prokaryotic Expression of NcSRS2 Gene of Neospora caninum%犬新孢子虫NcSRS2基因片段的克隆及原核表达

    Institute of Scientific and Technical Information of China (English)

    丁德; 贾立军; 其木格; 薛书江; 张守发

    2008-01-01

    以含有犬新孢子虫NcSRS2基因的质粒pMD18-NcSRS2为模板,应用PCR方法扩增NcSRS2基因,将该基因片段克隆至原核表达栽体pGEX-4T-2,构建了重组表达质粒pGEX-NcSRS2,转化大肠杆菌BL21中并诱导表达.结果显示,克隆的基因片段长1100bp,SDS-PAGE、Western blotting分析显示,重组质粒pGEX-NcSRS2在大肠杆菌中得到了高效表达.

  17. 76 FR 14970 - National Starch and Chemical Company, Salisbury, Rowan County, NC; Notice of Settlement

    Science.gov (United States)

    2011-03-18

    ... AGENCY National Starch and Chemical Company, Salisbury, Rowan County, NC; Notice of Settlement AGENCY... National Starch and Chemical Company Site located in Mobile, Mobile County, Alabama for publication. DATES..., identified by Docket ID No. EPA-RO4- SFUND-2011-0278 or Site name National Starch and Chemical...

  18. SYNTHESIS AND THERMAL STABILITY OF NANOCOMPOSITE nc-TiN/a-TiB2 THIN FILMS

    Institute of Scientific and Technical Information of China (English)

    Y.H. Lu; Z.F. Zhou; P. Sit; Y.G. Shen; K.Y. Li; H. Chen

    2005-01-01

    Several nc-TiN/a-TiB2 thin films comprised of nanocrystalline (nc-) TiN and amorphous (a-) TiB2phases were deposited on Si(100)at room temperature by reactive unbalanced dc magnetron sputtering, followed by vacuum annealed at 400, 600, 800 and 1000℃ for 1h, respectively. Effects of B content on microstructure, mechanical behaviors and thermal microstructure stability have been investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and nanoindentation measurements. The results indicated that B addition greatly affected both microstructure and mechanieal behavior of nc-TiN/a-TiB2 thin films. With increasing B content the grain size decreased. A maximum hardness value of about 33GPa was obtained at B content of about 19at. %. The improved mechanical properties of nc-TiN/a-TiB2films with the addition of B into TiN were attributed to their densified microstructure with development of fine grain size. Only addition of sufficient B could restrain grain growth during annealing. High B content resulted in high microstructure stability. The crystallization of amorphous matrix occurred at about 800℃, forming TiB or TiB2 crystallite, depending on B content. Before that no change in bonding configuration was found.

  19. 77 FR 50444 - Safety Zone, Atlantic Intracoastal Waterway; Carolina Beach, NC

    Science.gov (United States)

    2012-08-21

    ... Beach, NC AGENCY: Coast Guard, DHS. ACTION: Notice of Proposed Rulemaking. SUMMARY: The Coast Guard... Carolina Beach, North Carolina. The safety zone is necessary to provide for the safety of mariners on..., mile 295.6, at Carolina Beach, North Carolina. The safety zone will temporarily restrict...

  20. CyNC - towards a General Tool for Performance Analysis of Complex Distributed Real Time Systems

    DEFF Research Database (Denmark)

    Schiøler, Henrik; Jessen, Jan Jakob; Nielsen, Jens F. Dalsgaard

    2005-01-01

    The paper addresses the current state and the ongoing activities of a tool for performance analysis of complex real time systems. The tool named CyNC is based on network calculus allowing for the computation of backlogs and delays in a system from specified lower and upper bounds of external...

  1. Cloning and prokaryotic expression of the NcSRS2 gene from Xinjiang Nc-1 strain of Neospora caninum%犬新孢子虫新疆Nc-1株NcSRS2基因的克隆及原核表达

    Institute of Scientific and Technical Information of China (English)

    杨帆; 陈亮; 王莲芳; 巴音查汗

    2010-01-01

    根据GenBank中犬新孢子虫NcSRS2基因序列设计了1对引物,从新孢子虫病阳性牛血液中提取总DNA,经PCR扩增NcSRS2基因,将其插入原核表达质粒pGEX-4T-2中,重组质粒pGEX-4T-NcSRS2经测序确定后,转入表达菌株BL21,优化其表达条件,并探讨了GST-NcSRS2蛋白的生物活性.结果显示,在37℃条件下,经终浓度为0.5 mmol/L的IPTG诱导表达4 h后,获得融合蛋白.Western-blot分析表明该融合蛋白可与相应抗体发生特异性结合,rELISA检测与弓形虫和布鲁氏菌阳性血清无交叉反应.

  2. Ni-toughened nc-TiN/a-SiNx nanocomposite thin films

    NARCIS (Netherlands)

    Zhang, Sam; Sun, Deen; Fu, Yongqing; Pei, Y.T.; Hosson, J.Th.M. De

    2005-01-01

    Nanocomposite nc-TiN/a-SiNx thin films containing Ni up to similar to 40 at.% were prepared by co-sputtering of Ti, TiNi and Si3N4 targets in ArN2 gas atmosphere. Adjusting TiNi/(Ti+TiNi) target power ratio altered chemical composition, microstructure and consequently mechanical properties. X-ray ph

  3. 75 FR 54024 - Drawbridge Operation Regulation; Trent River, New Bern, NC

    Science.gov (United States)

    2010-09-03

    ... water. On behalf of the National Multiple Sclerosis (MS) Society and the City of New Bern NC, the North... Bern Ride and the City of New Bern Heritage Parade. Under this deviation, the drawbridge would be..., 2010 and Sunday, September 12, 2010, respectively; and for the City of New Bern Heritage Parade from...

  4. The parity-violating nucleon-nucleon force in the 1/N_c expansion

    CERN Document Server

    Phillips, Daniel R; Schat, Carlos

    2014-01-01

    Several experimental investigations have observed parity violation in nuclear systems-a consequence of the weak force between quarks. We apply the $1/N_c$ expansion of QCD to the P-violating T-conserving component of the nucleon-nucleon (NN) potential. We show there are two leading-order operators, both of which affect $\\vec{p}p$ scattering at order $N_c$. We find an additional four operators at $O(N_c^0 \\sin^2 \\theta_W)$ and six at $O(1/N_c)$. Pion exchange in the PV NN force is suppressed by $1/N_c$ and $\\sin^2 \\theta_W$, providing a quantitative explanation for its non-observation up to this time. The large-$N_c$ hierarchy of other PV NN force mechanisms is consistent with estimates of the couplings in phenomenological models. The PV observed in $\\vec{p}p$ scattering data is compatible with natural values for the strong and weak coupling constants: there is no evidence of fine tuning.

  5. 78 FR 79726 - Norfolk Southern Railway Company-Abandonment Exemption-in Gaston County, NC

    Science.gov (United States)

    2013-12-31

    ...-Exempt Abandonments to abandon approximately 0.5 miles of rail line between milepost HG 37.50 (near the line's crossing of Brooks Road) and milepost HG 38.00 (north of Robinson Road), in Crowders (Gastonia), Gaston County, N.C.\\1\\ The line traverses United States Postal Service Zip Code 28052. \\1\\ NSR...

  6. 75 FR 65278 - Pamlico Sound and Adjacent Waters, NC; Danger Zones for Marine Corps Operations

    Science.gov (United States)

    2010-10-22

    ... of Engineers, Department of the Army 33 CFR Part 334 Pamlico Sound and Adjacent Waters, NC; Danger... its regulations to establish one new danger zone in Pamlico Sound near Marine Corps Air Station Cherry Point, North Carolina. Establishment of this danger zone will enable the Marine Corps to control...

  7. 76 FR 30023 - Pamlico Sound and Adjacent Waters, NC; Danger Zones for Marine Corps Operations

    Science.gov (United States)

    2011-05-24

    ... of Engineers, Department of the Army 33 CFR Part 334 Pamlico Sound and Adjacent Waters, NC; Danger.... SUMMARY: The U.S. Army Corps of Engineers is amending its regulations to establish a new danger zone. This danger zone will enable the Marine Corps to control access and movement of persons, vessels and...

  8. 33 CFR 165.T05-0091 - Safety Zone; Alligator River, NC.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone; Alligator River, NC. 165.T05-0091 Section 165.T05-0091 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS Specific Regulated Navigation Areas and...

  9. Alternate 1/N_c Expansions and SU(3) Breaking from Baryon Lattice Results

    CERN Document Server

    Cherman, Aleksey; Lebed, Richard F

    2012-01-01

    A combined expansion in the number of QCD colors 1/N_c and SU(3) flavor breaking parameter epsilon has long been known to provide an excellent accounting for the mass spectrum of the lightest spin-1/2, 3/2 baryons when the quarks are taken to transform under the fundamental SU(N_c) representation, and in the final step N_c \\to 3 and epsilon is set to its physical value ~0.3. Subsequent work shows that placing quarks in the two-index antisymmetric SU(N_c) representation leads to quantitatively equally successful mass relations. Recent lattice simulations allow for varying the value of epsilon and confirm the robustness of the original 1/N_c relations. In this paper we show that the same conclusion holds for the antisymmetric quarks, and demonstrate that the mass relations also hold under alternate prescriptions for identifying physical baryons with particular members of the large N_c multiplets.

  10. 77 FR 44463 - Safety Zone, Atlantic Intracoastal Waterway; Emerald Isle, NC

    Science.gov (United States)

    2012-07-30

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone, Atlantic Intracoastal Waterway; Emerald... establishing a temporary safety zone on the waters of the Atlantic Intracoastal Waterway at Emerald Isle, North... maintenance of the NC 58 Fixed Bridge crossing the Atlantic Intracoastal Waterway, mile 226, at Emerald...

  11. Investigation on the foaming behaviors of NC-based gun propellants

    Institute of Scientific and Technical Information of China (English)

    Yu-xiang LI; Wei-tao YANG; San-jiu YING

    2014-01-01

    To prepare the porous NC-based (nitrocellulose-based) gun propellants, the batch foaming process of using supercritical CO2 as the physical blowing agent is used. The solubilities of CO2 in the single-base propellants and TEGDN (trimethyleneglycol dinitrate) propellants are measured by the gravimetric method, and SEM (scanning electron microscope) is used to observe the morphology of foamed propellants. The result shows that a large amount of CO2 could be dissolved in NC-based propellants. The experimental results also reveal that the energetic plasticizer TEGDN exerts an important influence on the pore structure. The triaxial tensile failure mechanism for solid-state nucleation is used to explain the nucleation of NC-based propellants in the solid state. Since some specific foaming behaviors of NC-based propellants can not be explained by the failure mechanism, a solid-state nucleation mechanism which revises the triaxial tensile failure mechanism is proposed and discussed. Copyright © 2014, China Ordnance Society. Production and hosting by Elsevier B.V. All rights reserved.

  12. 77 FR 4559 - Ecusta Mill Site, Pisgah Forest, Transylvania County, NC; Notice of Amended Settlement

    Science.gov (United States)

    2012-01-30

    ... AGENCY Ecusta Mill Site, Pisgah Forest, Transylvania County, NC; Notice of Amended Settlement AGENCY... Ecusta Mill Superfund Site located in Pisgah Forest, Transylvania County, North Carolina. DATES: The... by Site name Ecusta Mill Superfund Site by one of the following methods:...

  13. Data of evolutionary structure change: 1D5NC-1UNFX [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available msd> 1.0891029834747314 EVID> 1 1UNF...1D5NC-1UNFX 1D5N 1UNF C X ----SYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYV...NNANAALESL----PEFANLPVEELITKLDQLPADKKTVL---------RNNAGGHANHSLFWKGLKKGT--TLQGDLKAAIERDFGSVDNFKAEFEKAAASRFGSGW...HH EVID> 0 TRP CA 380 1UNF X 1UNF

  14. Hickory, N.C., Receives $200,000 EPA Brownfield Grants to Revitalize, Strengthen Local Economy

    Science.gov (United States)

    ATLANTA - At a press conference in Huntington, W.Va., today, the U.S. Environmental Protection Agency (EPA) announced a $200,000 Brownfields Area-Wide Planning (AWP) grant to the City of Hickory, N.C., for reuse planning that includes residential an

  15. 75 FR 81269 - Ward Transformer Superfund Site Raleigh, Wake County, NC; Notice of Settlements

    Science.gov (United States)

    2010-12-27

    ... AGENCY Ward Transformer Superfund Site Raleigh, Wake County, NC; Notice of Settlements AGENCY... Ward Transformer Superfund Site located in Raleigh, Wake County, North Carolina for publication. DATES... your comments, identified by Docket ID No. EPA-RO4- SFUND-2010-1053 or Site name Ward...

  16. 78 FR 14543 - Ward Transformer Superfund Site; Raleigh, Wake County, NC; Notice of Settlement

    Science.gov (United States)

    2013-03-06

    ... AGENCY Ward Transformer Superfund Site; Raleigh, Wake County, NC; Notice of Settlement AGENCY... Agency has entered into a settlement at the Ward Transformer Superfund Site located in Raleigh, Wake... EPA Region 4 contact Ms. Paula V. Painter. Submit your comments by Site name Ward...

  17. 33 CFR 334.412 - Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area.

    Science.gov (United States)

    2010-07-01

    ..., Harvey Point and adjacent waters, NC; restricted area. 334.412 Section 334.412 Navigation and Navigable... REGULATIONS § 334.412 Albemarle Sound, Pamlico Sound, Harvey Point and adjacent waters, NC; restricted area. (a) The area. Beginning on the north shore of Albemarle Sound and the easternmost tip of Harvey...

  18. 33 CFR 334.420 - Pamlico Sound and adjacent waters, N.C.; danger zones for Marine Corps operations.

    Science.gov (United States)

    2010-07-01

    ..., N.C.; danger zones for Marine Corps operations. 334.420 Section 334.420 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.420 Pamlico Sound and adjacent waters, N.C.; danger zones for Marine Corps operations....

  19. The End of Akıncı Corps in The Ottoman Empire

    Directory of Open Access Journals (Sweden)

    Mustafa Alkan

    2013-12-01

    Full Text Available It has been known that the Akıncıs were in the Ottoman Empire an extention of the corps which provided the border security of the Turkish states. They were named in the Seljuki period as “margraves”. Even the Ottomans were one of these margraves. Adopting a more centralist policy, the Ottoman Empire didn’t leave the border security to margraves as it was the case in Seljuks, but they assigned this job to some akıncı families. Evrenesoğulları in Albania and Dalmatia, Mihal-oğulları in Bosnia, Semendire and Serbia, Malkoç-oğulları in Silistre and Turhan-oğulları in Mora were the most famous ones among these families. The missions of the Akıncıs was to ensure the frontier security, to undertake reconnaissance mission in the regions which would be conquered, to gather intelligence, to raid the enemy territories and to act advanced guards, which was called as the fifth column activities at that time. It is assumed that Evranos Bey established the Akıncı corps. They were the light cavalry forces and had a certain organizational structure. Those with manor were registered in the account book with their descriptions. Their number exceeded fifty thousand during the period of Suleyman the Magnificient. The number of Akıncıs continued to increase until the 16th Century. In 1595, during the attacks carried out against Walachia Voivodina Mihail, who rebelled, the Akıncıs which stayed behind the Ottoman army, which was retreating over the wooden bridge, were nearly destroyed due to the inconsiderate act of Grand Vizier Sinan Pasha. After that incident the Akıncıs could not recover and their mission was undertaken by the Akkerman, Dobruca and Bucak Tatars and Crimea Khanate’s forces. With the exception of the short research of İ. Hakkı Uzunçarşılı, which is based on secondary sources, no serious study has been produced on the guild of Akıncıs by benefiting from the manorial books, muhimme books and local registry books

  20. Ground State Reactions of nC60 with Free Chlorine in Water.

    Science.gov (United States)

    Wu, Jiewei; Benoit, Denise; Lee, Seung Soo; Li, Wenlu; Fortner, John D

    2016-01-19

    Facile, photoenhanced transformations of water-stable C60 aggregates (nC60) to oxidized, soluble fullerene derivatives, have been described as key processes in understanding the ultimate environmental fate of fullerene based materials. In contrast, fewer studies have evaluated the aqueous reactivity of nC60 during ground-state conditions (i.e., dark conditions). Herein, this study identifies and characterizes the physicochemical transformations of C60 (as nC60 suspensions) in the presence of free chlorine, a globally used chemical oxidant, in the absence of light under environmentally relevant conditions. Results show that nC60 undergoes significant oxidation in the presence of free chlorine and the oxidation reaction rates increase with free chlorine concentration while being inversely related to solution pH. Product characterization by FTIR, XPS, Raman Spectroscopy, TEM, XRD, TOC, collectively demonstrates that oxidized C60 derivatives are readily formed in the presence of free chlorine with extensive covalent oxygen and even chlorine additions, and behave as soft (or loose) clusters in solution. Aggregation kinetics, as a function of pH and ionic strength/type, show a significant increase in product stabilities for all cases evaluated, even at pH values approaching 1. As expected with increased (surface) oxidation, classic Kow partitioning studies indicate that product clusters are relatively more hydrophilic than parent (reactant) nC60. Taken together, this work highlights the importance of understanding nanomaterial reactivity and the identification of corresponding stable daughter products, which are likely to differ significantly from parent material properties and behaviors.

  1. Determination of dispersive optical constants of nanocrystalline CdSe (nc-CdSe) thin films

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Kriti; Al-Kabbi, Alaa S.; Saini, G.S.S. [Centre of Advanced Study in Physics, Department of Physics, Panjab University, Chandigarh 160014 (India); Tripathi, S.K., E-mail: surya@pu.ac.in [Centre of Advanced Study in Physics, Department of Physics, Panjab University, Chandigarh 160014 (India)

    2012-06-15

    Highlights: ► nc-CdSe thin films are prepared by thermal vacuum evaporation technique. ► TEM analysis shows NCs are spherical in shape. ► XRD reveals the hexagonal (wurtzite) crystal structure of nc-CdSe thin films. ► The direct optical bandgap of nc-CdSe is 2.25 eV in contrast to bulk (1.7 eV). ► Dispersion of refractive index is discussed in terms of Wemple–DiDomenico single oscillator model. -- Abstract: The nanocrystalline thin films of CdSe are prepared by thermal evaporation technique at room temperature. These thin films are characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) and photoluminescence spectroscopy (PL). The transmission spectra are recorded in the transmission range 400–3300 nm for nc-CdSe thin films. Transmittance measurements are used to calculate the refractive index (n) and absorption coefficient (α) using Swanepoel's method. The optical band gap (E{sub g}{sup opt}) has been determined from the absorption coefficient values using Tauc's procedure. The optical constants such as extinction coefficient (k), real (ε{sub 1}) and imaginary (ε{sub 2}) dielectric constants, dielectric loss (tan δ), optical conductivity (σ{sub opt}), Urbach energy (E{sub u}) and steepness parameter (σ) are also calculated for nc-CdSe thin films. The normal dispersion of refractive index is described using Wemple–DiDomenico single-oscillator model. Refractive index dispersion is further analysed to calculate lattice dielectric constant (ε{sub L}).

  2. Cloning and bioinformatics analysis of Neospora caninum NcGRA2t gene%新孢子虫NcGRA2t基因的克隆与生物信息学分析

    Institute of Scientific and Technical Information of China (English)

    金春梅; 于龙政; 张守发

    2013-01-01

    为研究新孢子虫的血清学诊断方法,参照GenBank中已发表的新孢子虫NcGRA2基因序列设计了1对特异引物,扩增去掉新孢子虫NcGRA2基因N-末端信号肽的基因(NcGRA2t).根据NcGRA2t蛋白基因序列和推导的氨基酸序列进行同源性和抗原决定簇分析.结果表明,扩增得到的NcGRA2t基因与Nc-1株同源性为100%,与弓形虫的同源性为49%,NcGRA2t氨基酸有很强抗原性.

  3. The importance of neck circumference to thyromental distance ratio (NC/TM as a predictor of difficult intubation in obstructive sleep apnea (OSA patients

    Directory of Open Access Journals (Sweden)

    Hala Ezzat Abdel Naim

    2014-07-01

    Conclusion: Difficult intubation in OSA obese patients was independently associated with a Mallampati score of III or IV, and NC/TM ⩾5.15. Moreover, NC/TM yielded a high sensitivity, specificity and a negative predictive value.

  4. 四代核电NC-DCS产品解决方案简介%Brief Product Solution of 4th Generation of Nuclear NC-DCS

    Institute of Scientific and Technical Information of China (English)

    高景斌

    2014-01-01

    经历了福岛事件,核电的安全性更加被重视,四代核电因更安全性和经济性更加受到重视,是未来核电的发展方向。本文描述了具有我国自主知识产权的四代核电核心控制系统NC-DCS的产品解决方案,包括了解决方案的系统架构、网络、功能分配、主控制室设计、安全性冗余设计、通讯设计、校时设计等部分的内容。%After Fukushima, nuclear safety has been attached more attentions. Due to the more attentions on safety and economy, the four generation of nuclear power is the direction of development of nuclear power in the future. This paper describes the product solutions of NC-DCS with independent intellectual property rights of China's nuclear power core control system, including system architecture, solution of the network, function distribution, main control room design, safety redundancy design, communication design, time correction design and other parts design.

  5. Effect of combined treatment with micelle-incorporated cisplatin (NC-6004) and S-1 on human gastric cancer xenografts.

    Science.gov (United States)

    Kudo, Masahisa; Yamamoto, Yoshiyuki; Koga, Yoshikatsu; Hamaguchi, Tetsuya; Akimoto, Tetsuo; Yasunaga, Masahiro; Matsumura, Yasuhiro

    2016-12-01

    Combination therapy with S-1 and cisplatin (CDDP) is the standard chemotherapy for advanced gastric cancer in Japan; however, its administration requires hospitalization for hydration to prevent nephrotoxicity from CDDP. By contrast, NC-6004 appears to reduce the renal toxicity of CDDP and may be used on an outpatient basis. Thus, the effects of combined treatment with S-1 and NC-6004 were compared with those of S-1 and CDDP in a human gastric cancer model. In vitro cytotoxic effects were investigated in 44As3Luc, MKN45 and MKN74 human gastric cancer cell lines. The effects of NC-6004 and 5-fluorouracil (5-FU) were compared with the effects of CDDP and 5-FU using the combination index method. The in vivo antitumor effects of S-1/NC-6004 and S-1/CDDP were evaluated in mice bearing 44As3Luc xenografts. Both combinations exhibited synergistic activity in MKN45 and MKN74 cells and additive effects in 44As3Luc cells. Moreover, the in vivo antitumor effects did not differ between the S-1/NC-6004 and S-1/CDDP treatment groups. However, a significantly lower body weight loss was observed in S-1/NC-6004-treated mice compared with the S-1/CDDP-treated mice. Our data warrant a clinical evaluation of S-1/NC-6004 combination therapy.

  6. Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR.

    Science.gov (United States)

    Calderon, Brenda M; Conn, Graeme L

    2017-04-01

    The double-stranded RNA (dsRNA)-activated protein kinase (PKR) senses dsRNA produced during viral infection and halts cellular protein synthesis to block viral replication. How basal PKR activity is controlled in the absence of infection was unclear until the recent identification of a potential endogenous regulator, the cellular noncoding RNA 886 (nc886). However, nc886 adopts two distinct conformations for which the structural details and potential functional differences remain unclear. Here, we isolated and separately dissected the function of each form of nc886 to more clearly define the molecular mechanism of nc886-mediated PKR inhibition. We show that nc886 adopts two stable, noninterconverting RNA conformers that are functionally nonequivalent using complementary RNA structure probing and mutational analyses combined with PKR binding and activity assays. One conformer acts as a potent inhibitor, while the other is a pseudoinhibitor capable of weakly activating the kinase. We mapped the nc886 region necessary for high affinity binding and potent inhibition of PKR to an apical stem-loop structure present in only one conformer of the RNA. This structural feature is not only critical for inhibiting PKR autophosphorylation, but also the phosphorylation of its cellular substrate, the eukaryotic translation initiation factor 2α subunit. The identification of different activities of the nc886 conformers suggests a potential mechanism for producing a gradient of PKR regulation within the cell and reveals a way by which a cellular noncoding RNA can mask or present a structural feature to PKR for inhibition.

  7. Integrated CAD/CAM/CNC system based on STEP-NC and intelligent manufacturing

    Science.gov (United States)

    Du, Juan; Tian, Xitian; Zhang, Zhenming; Xu, Jianxin; Zhu, Mingquan

    2005-12-01

    In order to realize bi-direction exchange of information and knowledge sharing between CAD/CAM systems and CNC machines, a method of information integration was proposed based on process data model and STEP-NC neutral file. A frame of integrated CAD/CAM/CNC systems was established, and the key integration techniques including process data modeling based on XML form and automatic feature recognition were studied. Since the STEP-NC based CNC (STEP- CNC) system can undertake various intelligent functions that cannot be performed by the conventional CNC based on ISO 6983, the intelligent manufacturing functions of STEP- CNC system was also discussed. The presented methodology combining with the modern net and communication technologies provides an effective means for developing intelligent, integrated manufacturing systems for the 21 century.

  8. Assessment Method of Heavy NC Machine Reliability Based on Bayes Theory

    Institute of Scientific and Technical Information of China (English)

    张雷; 王太勇; 胡占齐

    2016-01-01

    It is difficult to collect the prior information for small-sample machinery products when their reliability is assessed by using Bayes method. In this study, an improved Bayes method with gradient reliability (GR) results as prior information was proposed to solve the problem. A certain type of heavy NC boring and milling machine was considered as the research subject, and its reliability model was established on the basis of its functional and structural characteristics and working principle. According to the stress-intensity interference theory and the reli-ability model theory, the GR results of the host machine and its key components were obtained. Then the GR results were deemed as prior information to estimate the probabilistic reliability (PR) of the spindle box, the column and the host machine in the present method. The comparative studies demonstrated that the improved Bayes method was applicable in the reliability assessment of heavy NC machine tools.

  9. 数控专用主板设计%The design of NC special motherboard

    Institute of Scientific and Technical Information of China (English)

    张赞秋; 高岩; 罗迪; 杨松山; 苏升力

    2012-01-01

    Application of NC system based on the harsh environment, presents a special CNC design of the motherboard, the motherboard integrated design. For vibration, dust, strong electromagnetic interference and other issues put forward a solution, discussed a number of ways so as to meet NC System requirements.%根据数控系统应用的严酷环境,介绍了一种数控专用主板的设计.该主板一体化设计,并针对振动、粉尘、强烈电磁干扰等问题提出了一个解决方案,讨论了一些方法使之满足数控系统要求.

  10. Entanglement Entropy Renormalization for the NC scalar field coupled to classical BTZ geometry

    CERN Document Server

    Jurić, Tajron

    2016-01-01

    In this work, we consider a noncommutative (NC) massless scalar field coupled to the classical nonrotational BTZ geometry. In a manner of the theories where the gravity emerges from the underlying scalar field theory, we study the effective action and the entropy derived from this noncommutative model. In particular, the entropy is calculated by making use of the two different approaches, the brick wall method and the heat kernel method designed for spaces with conical singularity. We show that the UV divergent structures of the entropy, obtained through these two different methods, agree with each other. It is also shown that the same renormalization condition that removes the infinities from the effective action can also be used to renormalize the entanglement entropy for the same system. Besides, the interesting feature of the NC model considered here is that it allows an interpretation in terms of an equivalent system comprising of a commutative massive scalar field, but in a modified geometry; that of th...

  11. Sublimation of the endohedral fullerene Er(3)N@C(80).

    Science.gov (United States)

    Stibor, Alexander; Schefzyk, Hannah; Fortágh, József

    2010-10-28

    The heat of sublimation of the endohedral metallofullerene Er(3)N@C(80) was measured via Knudsen effusion mass spectrometry. The large molecule consists of a C(80) fullerene cage which is stabilized by a complex of three erbium atoms bounded to a nitrogen atom and has a mass of 1475 amu. The mass spectrum at a temperature of 1045 K and the relative intensities of the thermal fractions of Er(3)N@C(80) are provided. We also discuss possible thermal decomposition processes for these particles. By measuring the quantity of evaporated molecules in thermal equilibrium using a quadrupole mass spectrometer in a temperature range between 782 K and 1128 K, a value for the sublimation enthalpy of ΔH(sub) = 237 ± 7 kJ mol(-1) is obtained via the second-law method.

  12. An automatic 3D CAD model errors detection method of aircraft structural part for NC machining

    Directory of Open Access Journals (Sweden)

    Bo Huang

    2015-10-01

    Full Text Available Feature-based NC machining, which requires high quality of 3D CAD model, is widely used in machining aircraft structural part. However, there has been little research on how to automatically detect the CAD model errors. As a result, the user has to manually check the errors with great effort before NC programming. This paper proposes an automatic CAD model errors detection approach for aircraft structural part. First, the base faces are identified based on the reference directions corresponding to machining coordinate systems. Then, the CAD models are partitioned into multiple local regions based on the base faces. Finally, the CAD model error types are evaluated based on the heuristic rules. A prototype system based on CATIA has been developed to verify the effectiveness of the proposed approach.

  13. Resonant tunnelling in nc-Si/SiO2 multilayers at room temperature

    Institute of Scientific and Technical Information of China (English)

    Chen Deyuan

    2011-01-01

    Nc-Si/SiO2 multilayers were fabricated on silicon wafers in a plasma enhanced chemical vapour deposition system using in situ oxidation technology,followed by three-step thermal treatments.Carrier transportation at room temperature is characterized by current voltage measurement,and negative different conductances can be observed both under forward and negative biases,which is explained by resonant tunnelling.The resonant tunnelling peak voltage is related to the thicknesses of the nc-Si and SiO2 sublayers.And the resonant tunnelling peak voltage under negative bias is larger than that under forward bias.An energy band diagram and an equivalent circuit diagram were constructed to analyze and explain the above transportation process and properties.

  14. DYNAMIC CHARACTERISTICS ON PRECISION NC LATHE BASED ON MULTI-BODY SYSTEM THEORY

    Institute of Scientific and Technical Information of China (English)

    Wu Nanxing; Sun Qinghong; Zhang Yonghong; Yu Dongling

    2005-01-01

    Based on multi-body system theory and the mainshaft system of precision NC lathe as object investigated, it is treated as a coupled rigid-flexible multi-body system which is made up of some rigid and elastic bodies in an especial linking mode. And a dynamic model is established. The problems of computing vibration characteristics are resolved by using multi-body system transfer matrix method. Results show that the mainshaft system of NC lathe is in the stable and reliable working area all the time. The method is simple and easy, the idea is clear. In addition, the method can be easily used and popularized in the other multi-body system.

  15. $1/N_C$ Corrections to $g_A$ in the Light of PCAC

    CERN Document Server

    Alkofer, R

    1993-01-01

    We comment on recently discovered $1/N_C$ corrections to the ` nucleon axial current in the framework of the Nambu--Jona-Lasinio soliton. This kind of corrections arises only for a special treatment of ordering ambiguities of collective coordinates and operators in the semiclassical quantization. In addition to the missing derivation of this special quantization scheme from first principles its na\\"\\i ve application violates partial conservation of the axial current (PCAC). We show how within this scheme PCAC can be restored and determine the corresponding $1/N_C$ corrections to the equation of motion for the chiral soliton. The resulting self-consistent solution allows to evaluate the nucleon axial coupling constant $g_A$ directly as a matrix element of the axial current as well as indirectly from the pion profile function. Enhancement is found for those baryon properties which are sensitive to the long range behavior of the pion profile.

  16. Research on cubic polynomial acceleration and deceleration control model for high speed NC machining

    Institute of Scientific and Technical Information of China (English)

    Hong-bin LENG; Yi-jie WU; Xiao-hong PAN

    2008-01-01

    To satisfy the need of high speed NC (numerical control) machining, an acceleration and deceleration (aec/dec) control model is proposed, and the speed curve is also constructed by the cubic polynomial. The proposed control model provides continuity of acceleration, which avoids the intense vibration in high speed NC machining. Based on the discrete characteristic of the data sampling interpolation, the acc/dec control discrete mathematical model is also set up and the discrete expression of the theoretical deceleration length is obtained furthermore. Aiming at the question of hardly predetermining the deceleration point in acc/dec control before interpolation, the adaptive acc/dec control algorithm is deduced from the expressions of the theoretical deceleration length. The experimental result proves that the acc/dec control model has the characteristic of easy implementation, stable movement and low impact. The model has been applied in multi-axes high speed micro fabrication machining successfully.

  17. Aerobic oxidation of hydroxymethylfurfural and furfural by using heterogeneous Cox Oy -N@C catalysts.

    Science.gov (United States)

    Deng, Jin; Song, Hai-Jie; Cui, Min-Shu; Du, Yi-Ping; Fu, Yao

    2014-12-01

    2,5-Furandicarboxylic acid (FDCA) is considered to be a promising replacement for terephthalic acid since they share similar structures and properties. In contrast to FDCA, 2,5-furandicarboxylic acid methyl (FDCAM) has properties that allow it to be easily purified. In this work, we reported an oxidative esterification of 5-hydroxymethylfurfural (HMF) and furfural to prepare corresponding esters over Cox Oy -N@C catalysts using O2 as benign oxidant. High yield and selectivity of FDCAM and methyl 2-furoate were obtained under optimized conditions. Factors which influenced the product distribution were examined thoroughly. The Cox Oy -N@C catalysts were recycled five times and no significant loss of activity was detected. Characterization of the catalysts could explain such phenomena. Using XPS and TGA, we made a thorough investigation of the effects of ligand and pyrolysis temperature on catalyst activity.

  18. The NC2 domain of type IX collagen determines the chain register of the triple helix.

    Science.gov (United States)

    Boudko, Sergei P; Bächinger, Hans Peter

    2012-12-28

    Precise mapping and unraveling the mechanism of interaction or degradation of a certain type of collagen triple helix requires the generation of short and stable collagenous fragments. This is a great challenge especially for hetero-trimeric collagens, where chain composition and register (stagger) are important factors. No system has been reported that can be efficiently used to generate a natural collagenous fragment with exact chain composition and desired chain register. The NC2 domain (only 35-50 residues) of FACIT collagens is a potent trimerization domain. In the case of type IX collagen it provides the efficient selection and hetero-trimerization of three distinct chains. The ability of the NC2 domain to determine the chain register of the triple helix is studied. We generated three possible sequence combinations (α1α1α2, α1α2α1, α2α1α1) of a type I collagen fragment (the binding region for the von Willebrand factor A3 domain) attached to the NC2 domain. In addition, two control combinations were produced that constitute homo-trimers of (α1)(3) or (α2)(3). For the hetero-trimeric constructs, α1α1α2 demonstrated a higher melting temperature than the other two. Binding experiments with the von Willebrand factor A3 domain revealed the homo-trimer of (α1)(3) as the strongest binding construct, whereas the homo-trimer of (α2)(3) showed no binding. For hetero-trimers, α1α1α2 was found to be the strongest binding construct. Differences in thermal stability and binding to the A3 domain unambiguously demonstrate that the NC2 domain of type IX collagen determines not only the chain composition but also the chain register of the adjacent triple helix.

  19. Discretization effects in $N_c=2$ QCD and Random Matrix Theory

    CERN Document Server

    Kieburg, Mario; Zafeiropoulos, Savvas

    2015-01-01

    We summarize the analytical solution of the Chiral Perturbation Theory for the Hermitian Wilson Dirac operator of $N_c=2$ QCD with quarks in the fundamental representation. Results have been obtained for the quenched microscopic spectral density, the distribution of the chiralities over the real modes and the chiral condensate. The analytical results are compared with results from a Monte Carlo simulation of the corresponding Random Matrix Theory.

  20. Electromagnetic Form Factors of Hadrons in Dual-Large $N_c$ QCD

    CERN Document Server

    Dominguez, C A

    2010-01-01

    In this talk, results are presented of determinations of electromagnetic form factors of hadrons (pion, proton, and $\\Delta(1236)$) in the framework of Dual-Large $N_c$ QCD (Dual-$QCD_\\infty$). This framework improves considerably tree-level VMD results by incorporating an infinite number of zero-width resonances, with masses and couplings fixed by the dual-resonance (Veneziano-type) model.

  1. Development of a community cancer education program: the Forsyth County, NC cervical cancer prevention project.

    OpenAIRE

    Michielutte, R; Dignan, M B; Wells, H B; Young, L. D.; Jackson, D S; Sharp, P C

    1989-01-01

    The authors outline the development and implementation of a public health education program for cervical cancer screening among black women in Forsyth County, NC. The educational program includes distributing electronic and printed information media messages, a program of direct education for women, and providing information on current issues in cervical screening to primary-care physicians. Program development was based on social marketing principles, the PRECEDE model, and the communication...

  2. STUDY ON NEW METHOD OF IDENTIFYING GEOMETRIC ERROR PARAMETERS FOR NC MACHINE TOOLS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The methods of identifying geometric error parameters for NC machine tools are introduced. According to analyzing and comparing the different methods, a new method-displacement method with 9 lines is developed based on the theories of the movement errors of multibody system (MBS). A lot of experiments are also made to obtain 21 terms geometric error parameters by using the error identification software based on the new method.

  3. 长虹NC-2机心通病检修

    Institute of Scientific and Technical Information of China (English)

    何金华

    2001-01-01

    @@ 长虹NC-2机心是九十年代初长虹公司和日本东芝公司联合研制并成功开发的机心.该机心已陪同用户走过了近十个春秋,也大批量陆续进入了故障期.在维修中,发现该机心有如下六种通病.

  4. $(\\alpha')^4$ Corrections in Holographic Large $N_c$ QCD and $\\pi - \\pi$ Scattering

    CERN Document Server

    Parthasarathy, R

    2007-01-01

    We calculate the ${\\alpha'}^4$ corrections to the non-Abelian DBI action on the $D8$-brane in the holographic dual of large $N_c$ QCD proposed by Sakai and Sugimoto. These give rise to higher derivative terms, in particular, four derivative contact terms for the pion field with the coupling uniquely determined. We calculate the pion-pion scattering amplitude near threshold. The results respecting unitarity are in agreement with the experimental curves.

  5. Resonance sum rules from large $N_C$ and partial wave dispersive analysis

    CERN Document Server

    Guo, Zhi-Hui

    2008-01-01

    Combining large $N_C$ techniques and partial wave dispersion theory to analyze the $\\pi\\pi$ scattering, without relying on any explicit resonance lagrangian, some interesting results are derived: (a) a general KSRF relation including the scalar meson contribution; (b) a new relation between resonance couplings, with which we have made an intensive analysis in several specific models; (c) low energy constants in chiral perturbation theory related with $\\pi\\pi$ scattering in terms of the mass and decay width of resonances.

  6. Density of Saturated Nuclear Matter at Large $N_{c}$ and Heavy Quark Mass Limits

    CERN Document Server

    Adhikari, Prabal; Datta, Ishaun

    2013-01-01

    We exhibit the existence of stable, saturated nuclear matter in the large $N_{c}$ and heavy quark mass limits of QCD. In this limit, baryons (with the same spin flavor structure) interact at leading order in $N_{c}$ via a repulsive interaction due to the Pauli exclusion principle and at subleading order in $1/N_c$ via the exchange of glueballs. Assuming that the lightest glueball is a scalar, which implies that the subleading baryon interaction is attractive, we find that nuclear matter saturates since the subleading attractive interaction is longer ranged than the leading order repulsive one. We find that the saturated matter is in the form of a crystal with either a face-centered cubic or a hexagonal-close-packed symmetry with baryon densities of $\\mathcal{O}((\\, \\tilde{\\alpha}_{s} m_q (\\ln (N_{c}m_{q}\\Lambda_{\\textrm{QCD}}^{-1}))^{-1})^3 )$. Remarkably, the leading order expression for the density of saturated nuclear matter is independent of the lighest glueball mass and scalar-glueball-baryon coupling in...

  7. Bayesian Reliability Modeling and Assessment Solution for NC Machine Tools under Small-sample Data

    Institute of Scientific and Technical Information of China (English)

    YANG Zhaojun; KAN Yingnan; CHEN Fei; XU Binbin; CHEN Chuanhai; YANG Chuangui

    2015-01-01

    Although Markov chain Monte Carlo(MCMC) algorithms are accurate, many factors may cause instability when they are utilized in reliability analysis; such instability makes these algorithms unsuitable for widespread engineering applications. Thus, a reliability modeling and assessment solution aimed at small-sample data of numerical control(NC) machine tools is proposed on the basis of Bayes theories. An expert-judgment process of fusing multi-source prior information is developed to obtain the Weibull parameters’ prior distributions and reduce the subjective bias of usual expert-judgment methods. The grid approximation method is applied to two-parameter Weibull distribution to derive the formulas for the parameters’ posterior distributions and solve the calculation difficulty of high-dimensional integration. The method is then applied to the real data of a type of NC machine tool to implement a reliability assessment and obtain the mean time between failures(MTBF). The relative error of the proposed method is 5.8020×10-4 compared with the MTBF obtained by the MCMC algorithm. This result indicates that the proposed method is as accurate as MCMC. The newly developed solution for reliability modeling and assessment of NC machine tools under small-sample data is easy, practical, and highly suitable for widespread application in the engineering field; in addition, the solution does not reduce accuracy.

  8. Joint NC-ARQ and AMC for QoS-Guaranteed Mobile Multicast

    Directory of Open Access Journals (Sweden)

    Schwefel Hans-Peter

    2010-01-01

    Full Text Available In mobile multicast transmissions, the receiver with the worst instantaneous channel condition limits the transmission data rate under the desired Quality-of-Service (QoS constraints. If Automatic Repeat reQuest (ARQ schemes are applied, the selection of Adaptive Modulation and Coding (AMC mode will not necessarily be limited by the worst channel anymore, and improved spectral efficiency may be obtained in the efficiency-reliability tradeoff. In this paper, we first propose a Network-Coding-based ARQ (NC-ARQ scheme in its optimal form and suboptimal form (denoted as Opt-ARQ and SubOpt-ARQ, resp. to solve the scalability problem of applying ARQ in multicast. Then we propose two joint NC-ARQ-AMC schemes, namely, the Average PER-based AMC (AvgPER-AMC with Opt-ARQ and AvgPER-AMC with SubOpt-ARQ in a cross-layer design framework to maximize the average spectral efficiency per receiver under specific QoS constraints. The performance is analyzed under Rayleigh fading channels for different group sizes, and numerical results show that significant gains in spectral efficiency can be achieved with the proposed joint NC-ARQ-AMC schemes compared with the existing multicast ARQ and/or AMC schemes.

  9. The C$^{14}$N/C$^{15}$N Ratio in Diffuse Molecular Clouds

    CERN Document Server

    Ritchey, Adam M; Lambert, David L

    2015-01-01

    We report the first detection of C$^{15}$N in diffuse molecular gas from a detailed examination of CN absorption lines in archival VLT/UVES spectra of stars probing local diffuse clouds. Absorption from the C$^{15}$N isotopologue is confidently detected (at $\\gtrsim4\\sigma$) in three out of the four directions studied and appears as a very weak feature between the main $^{12}$CN and $^{13}$CN absorption components. Column densities for each CN isotopologue are determined through profile fitting, after accounting for weak additional line-of-sight components of $^{12}$CN, which are seen in the absorption profiles of CH and CH$^+$ as well. The weighted mean value of C$^{14}$N/C$^{15}$N for the three sight lines with detections of C$^{15}$N is $274\\pm18$. Since the diffuse molecular clouds toward our target stars have relatively high gas kinetic temperatures and relatively low visual extinctions, their C$^{14}$N/C$^{15}$N ratios should not be affected by chemical fractionation. The mean C$^{14}$N/C$^{15}$N ratio ...

  10. l3a81nc.m77t - MGD77 data file for Geophysical data from field activity L-3A-81-NC in Central Coast, Northern California from 04/16/1981 to 04/26/1981

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry, gravity, and magnetic data along with DGPS navigation data was collected as part of field activity L-3A-81-NC in Central Coast, Northern...

  11. 新孢子虫NcSAG4基因克隆及原核表达%Cloning and prokaryotic expression of the Neospora caninum NcSAG4 gene in Escherichia coli

    Institute of Scientific and Technical Information of China (English)

    李赫; 丁鹤; 李建华; 刘畅; 宫鹏涛; 王伟利; 杨举; 张国才; 张西臣

    2012-01-01

    Objective To construct a prokaryotic expression vector of the Neospora caninum NcSAG4 gene and express it in Escherichia coli. Methods Special primers were designed on the basis of the reported Neosporosis NcSAG4 gene. The NcSAG4 gene was amplified by PCR from the total DNA of N. caninum and was cloned into pMD-18-T to construct pMD-NcSAG4. The plasmid pMD-NcSAG4 was then digested with restriction ribozymes and subcloned into prokaryotic expression plasmid pGEX-T to construct pGEX-NcSAG4. It was then expressed in E. coli BL21 (DE3) induced with IPTG. The fusion product was identified by SDS-PAGE and Western blot. Results A prokaryotic expression vector of the NcSAG4 gene was constructed and expressed in E. coli. Induced with IPTG, the expressed recombinant protein was detected as a band of 18. 79 ku by SDS-PAGE. A special reaction band to anti-NcSAG4 sera was observed in Western blot. Conclusion The fusion protein of NcSAG4 gene was successfully expressed in prokaryotic cells and it has the potential to facilitate diagnosis via ELISA.%目的 构建新孢子虫NcSAG4基因原核表达载体,并在大肠埃希菌BL21 (DE3)中表达.方法 根据新孢子虫NcSAG4基因序列设计特异性引物,以新孢子虫总核酸为模板PCR扩增目的片段,与pMD-18-T连接,构建克隆载体pMD-NcSAG4,经双酶切后回收目的片段,与表达载体pGEX-T连接,构建原核表达载体pGEX-NcSAG4,用IPTG诱导,通过SDS-PAGE及Western blot进行鉴定.结果 成功构建了新孢子虫NcSAG4基因原核表达载体pGEX-Nc-SAG4;SDS-PAGE电泳显示,在IPTG诱导下阳性菌高效表达了分子质量单位为18.79 ku的蛋白质;Western blot显示表达产物可被抗新孢子虫的多克隆血清识别.结论 成功构建了NcSAG4基因原核表达载体,并在大肠埃希菌BL21(DE3)中高效表达,为建立经济、实用的诊断新孢子虫病的ELISA方法奠定了基础.

  12. l477nc.m77t - MGD77 data file for Geophysical data from field activity L-4-77-NC in Northern California from 05/10/1977 to 05/21/1977

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry, gravity, and magnetic data along with DGPS navigation data was collected as part of field activity L-4-77-NC in Northern California from...

  13. l382nc.m77t - MGD77 data file for Geophysical data from field activity L-3-82-NC in Off San Mateo County, Northern California from 02/27/1982 to 03/01/1982

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry, gravity, and magnetic data along with DGPS navigation data was collected as part of field activity L-3-82-NC in Off San Mateo County,...

  14. l282nc.m77t - MGD77 data file for Geophysical data from field activity L-2-82-NC in Off San Mateo, Northern California from 02/07/1982 to 02/12/1982

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry, gravity, and magnetic data along with DGPS navigation data was collected as part of field activity L-2-82-NC in Off San Mateo, Northern...

  15. c180nc.m77t - MGD77 data file for Geophysical data from field activity C-1-80-NC in Monterey Bay, Northern California from 05/21/1980 to 05/22/1980

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with transit satellite navigation data was collected as part of field activity C-1-80-NC in Monterey Bay, Northern California from...

  16. Molecular Dynamics Simulation and Experimental Study of DNTF on Plasticizing Properties of NC%DNTF 对 NC 塑化特性的分子动力学模拟及实验研究

    Institute of Scientific and Technical Information of China (English)

    孟玲玲; 齐晓飞; 王江宁; 樊学忠

    2015-01-01

    为研究 DNTF 对 CMDB 推进剂力学性能的作用机理,通过分子动力学模拟方法建立了 NC 纯物质和 NC/DNTF 共混物分子模型,研究了 DNTF 对 NC 塑化过程中微观结构的影响,采用拉伸试验研究了 DNTF 对 CMDB推进剂力学性能的影响。结果表明,DNTF 与 NC 分子形成氢键,使 NC 内分子的氢键减弱,NC 分子的刚性降低;加入 DNTF 后,DNTF-CMDB 推进剂的抗拉强度降低、延伸率增加;20℃时延伸率由8.69%增加到33.6%,50℃时延伸率由14.86%增加到45.6%。分子动力学模拟计算结果与拉伸试验结果一致。%To investigate the acting mechanism of 3,4-dinitrofurazanfuroxan (DNTF)on the mechanical properties of CMDB propellants,the molecular models of nitrocellulose (NC)pure substance and NC/ DNTF blends were established by molecular dynamics simulation method.The effects of DNTF on the microstructure of NC in plastici-zing process were studied.The effects of DNTF on the mechanical properties of CMDB propellants were explored using the tensile test.Results show that DNTF and NC molecules form hydrogen bonds,which make the inner-molecule hydrogen bonds for NC weaken and the rigidity of NC molecules reduce.After addition of DNTF in CMDB propellants,the elongation of the DNTF-CMDB propellant increases,while the tensile strength decreases.The elongation increases from 8.69% to 33.6% at 20℃ and increases from 14.86 to 45.6% at 50℃.The results of molecular dynamics simulation are in agreement with those of tensile test.

  17. Cloning and prokaryotic expression of bovine Neospora caninum NcGRA7 gene%牛源犬新孢子虫NcGRA7基因的克隆及原核表达分析

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发; 李男礼

    2013-01-01

    为了解牛源犬新孢子虫NcGRA7基因的生物学特性,本实验采用PCR技术扩增牛源犬新孢子虫NcGRA7基因,并连接至pMD-18T载体中,构建重组质粒pMD 18-NcGRA7,经PCR、酶切鉴定及测序分析,将NcGRA7基因连接到原核表达载体pGEX-4T-1中,构建重组表达质粒pGEX-NcGRA7,转化大肠杆菌BL21,筛选阳性克隆,将PCR和酶切鉴定正确的重组质粒进行IPTG诱导表达,SDS-PAGE和westem blot分析表达产物.结果表明,扩增的NcGRA7基因片段大小为701 bp,编码233个氨基酸,与GenBank中登录的NcGRA7(AF176649)核苷酸序列同源性为98.7%;western blot分析表达蛋白的分子量为52 ku,具有较好的反应原性.本实验为犬新孢子虫NcGRA7基因疫苗研究奠定了基础.

  18. 新孢子虫NcGRA2t基因的原核表达及鉴定%Prokaryotic expression of Neospora caninum NcGRA2t and identification of the bioactivity of expressed product

    Institute of Scientific and Technical Information of China (English)

    金春梅; 于龙政; 张守发

    2015-01-01

    为研究新孢子虫GRA2t基因的原核表达及其表达产物的免疫活性,用EcoRI和XhoI限制性内切酶从pMD20-NcGRA2t上切下NcGRA2t基因,克隆入pGEX-4T1中构建NcGRA2t-GST融合蛋白基因的重组表达载体pGEX-4T1-Nc-GRA2t.经测序验证后,在大肠杆菌BL-21 (DE3)中诱导表达,表达产物采用谷胱甘肽-琼脂糖层析柱进行纯化.用Western blotting方法,以犬感染新孢子虫Nc1株的血清鉴定表达产物的活性.结果,构建了pGEX-4T1-NcGRA2t原核表达质粒,并在大肠杆菌BL-21(DE3)中诱导表达分子量为46 ku的NcGRA2t-GST融合蛋白,表达产物经谷胱甘肽-琼脂糖层析柱纯化后,得到N端带有GST标签的NcGAR2t蛋白.Western blotting结果显示,表达产物具有生物学活性.

  19. Rheological properties of gamma irradiated [Me3NC2H4OH]+[Zn2Cl5]- and [Me3NC2H4OH]+[Zn3Cl7]- ionic liquids

    Institute of Scientific and Technical Information of China (English)

    李倩妹; 罗迎社; 吴国忠; 陈仕谋

    2008-01-01

    The objective of this work is to verify the rheological behavior of irradiated [Me3NC2H4OH]+[Zn2Cl5]-and [Me3NC2H4OH]+[Zn3Cl7]-ionic liquids in comparison to the unirradiated ones,the viscosities were measured by a strain-control experiment under different irradiation doses’ samples(0,10,20,50,100 kGy) at different shear rates and temperatures.The curves of shear stress against shear rate present that the viscosity of ionic liquid is insensitive to shear rate;the viscosity of ionic liquids decreases with increasing temperature,and can be fitted by Arrhenius equation very well.Gamma radiation causes a decrease of viscosity of [Me3NC2H4OH]+[Zn3Cl7]-by greater than 10%,but it does not impair the viscosity of [Me3NC2H4OH]+[Zn2Cl5]-(within the experimental error) except 20 kGy irradiated sample.The results show that the radiation stability of [Me3NC2H4OH]+[Zn2Cl5]-is higher than that of [Me3NC2H4OH]+[Zn3Cl7]-.

  20. Generating SU(Nc) pure gauge lattice QCD configurations on GPUs with CUDA and OpenMP

    CERN Document Server

    Cardoso, Nuno

    2011-01-01

    The starting point of any lattice QCD computation is the generation of a Markov chain of gauge field configurations. Due to the large number of lattice links and due to the matrix multiplications, generating SU(Nc) lattice QCD configurations is a highly demanding computational task, requiring advanced computer parallel architectures such as clusters of several Central Processing Units (CPUs) or Graphics Processing Units (GPUs). In this paper we present and explore the performance of CUDA codes for NVIDIA GPUs to generate SU(Nc) lattice QCD pure gauge configurations. Our implementation in one GPU uses CUDA and in multiple GPUs uses OpenMP and CUDA. We present optimized CUDA codes SU(2), SU(3) and SU(4). We also show a generic SU(Nc) code for Nc$\\,\\geq 4$ and compare it with the optimized version of SU(4). Our codes are publicly available for free use by the lattice QCD community.

  1. Correlation between Light Emissions from Amorphous-Si:H/SiO2 and nc-Si/SiO2 Multilayers

    Institute of Scientific and Technical Information of China (English)

    MA Zhong-Yuan; HUANG Xin-Fan; CHEN Kun-Ji; FENG Duan; HAN Pei-Gao; LI Wei; CHEN De-Yuan; WEI De-Yuan; QIAN Bo; LI Wei; XU Jun; XU Ling

    2007-01-01

    We investigate the properties of light emission from amorphous-Si:H/SiO2 and nc-Si/SiO2 multilayers (MLs). The size dependence of light emission is well exhibited when the a-Si:H sublayer thickness is thinner than 4nm and the interface states are well passivated by hydrogen. For the nc-Si/SiO2 MLs, the oxygen modified interface states and nanocrystalline silicon play a predominant role in the properties of light emission. It is found that the light emission from nc-Si/SiO2 is in agreement with the model of interface state combining with quantum confinement when the size of nc-Si is smaller than 4 nm. The role of hydrogen and oxygen is discussed in detail.

  2. Resonant Tunnelling and Storage of Electrons in Si Nanocrystals within a-SiNx/nc-Si/a-SiNx Structures

    Institute of Scientific and Technical Information of China (English)

    WANG Xiang; HUANG Jian; ZHANG Xian-Gao; DING Hong-Lin; YU Lin-Wei; HUANG Xin-Fan; LI Wei; XU Jun; CHEN Kun-Ji

    2008-01-01

    @@ The a-SiNx/nanocrystalline silicon (nc-Si)/a-SiNx sandwiched structures with asymmetric double-barrier are fabricated in a plasma enhanced chemical vapour deposition (PECVD) system on p-type Si substrates. The nc-Si layer in thickness 5nm is fabricated from a hydrogen-diluted silane gas by the layer-by-layer deposition technique. The thicknesses of tunnel and control SiNx layers are 3nm and 20nm,respectively. Frequency-dependent capacitance spectroscopy is used to study the electron tunnelling and the storage in the sandwiched structures.Distinct frequency-dependent capacitance peaks due to electrons tunnelling into the nc-Si dots and capacitance-voltage (C- V) hysteresis characteristic due to electrons storage in the nc-Si dots are observed with the same sample.

  3. Error Analysis and Its Offset on the NC Lathe Machine in Cutting a Semi-Sphere Surface

    Institute of Scientific and Technical Information of China (English)

    ZHENG Yu-cai; LI Cheng-zhi; LIU Chang-rong; LIU Tao; GUO Xiu-hua

    2007-01-01

    This paper analyzed the errors that occurred by leaving the shape of the cutting edge out of consideration on a NC lathe machine in cutting a semi-sphere surface and brought forward a method to offset these errors and the correct calculated formula for some parameters on the basis of experiments. It has increased the manufacturing accuracy of the semi-sphere surface on the NC lathe machine.

  4. Implementation of Real-Time Machining Process Control Based on Fuzzy Logic in a New STEP-NC Compatible System

    Directory of Open Access Journals (Sweden)

    Po Hu

    2016-01-01

    Full Text Available Implementing real-time machining process control at shop floor has great significance on raising the efficiency and quality of product manufacturing. A framework and implementation methods of real-time machining process control based on STEP-NC are presented in this paper. Data model compatible with ISO 14649 standard is built to transfer high-level real-time machining process control information between CAPP systems and CNC systems, in which EXPRESS language is used to define new STEP-NC entities. Methods for implementing real-time machining process control at shop floor are studied and realized on an open STEP-NC controller, which is developed using object-oriented, multithread, and shared memory technologies conjunctively. Cutting force at specific direction of machining feature in side mill is chosen to be controlled object, and a fuzzy control algorithm with self-adjusting factor is designed and embedded in the software CNC kernel of STEP-NC controller. Experiments are carried out to verify the proposed framework, STEP-NC data model, and implementation methods for real-time machining process control. The results of experiments prove that real-time machining process control tasks can be interpreted and executed correctly by the STEP-NC controller at shop floor, in which actual cutting force is kept around ideal value, whether axial cutting depth changes suddenly or continuously.

  5. AREVA-Aging Management Concepts and Tools

    Energy Technology Data Exchange (ETDEWEB)

    Zander, A.; Nopper, H.

    2014-07-01

    n case of long term operation (LTO) it is necessary to ensure that safety and safety relevant systems, structures and components continue to perform their intended functions during long term operation. In order to fulfill these requirements a plant-wide and systematic Aging and Plant Life Management is essential. (Author)

  6. First Industrial Tests of a Matrix Monitor Correction for the Differential Die-away Technique of Historical Waste Drums

    Energy Technology Data Exchange (ETDEWEB)

    Antoni, Rodolphe; Passard, Christian; Perot, Bertrand [CEA Cadarache DEN/Nuclear Measurement Laboratory, 13108 Saint-Paul lez Durance (France); Batifol, Marc; Vandamme, Jean-Christophe [Nuclear Measurement Team, AREVA NC, La Hague plant F-50444 Beaumont-Hague (France); Grassi, Gabriele [AREVA NC, 1 place Jean-Millier, 92084 Paris-La-Defense cedex (France)

    2015-07-01

    The fissile mass in radioactive waste drums filled with compacted metallic residues (spent fuel hulls and nozzles) produced at AREVA NC La Hague reprocessing plant is measured by neutron interrogation with the Differential Die-away measurement Technique (DDT). In the next years, old hulls and nozzles mixed with Ion-Exchange Resins will be measured. The ion-exchange resins increase neutron moderation in the matrix, compared to the waste measured in the current process. In this context, the Nuclear Measurement Laboratory (LMN) of CEA Cadarache has studied a matrix effect correction method, based on a drum monitor, namely a 3He proportional counter located inside the measurement cavity. After feasibility studies performed with LMN's PROMETHEE 6 laboratory measurement cell and with MCNPX simulations, this paper presents first experimental tests performed on the industrial ACC (hulls and nozzles compaction facility) measurement system. A calculation vs. experiment benchmark has been carried out by performing dedicated calibration measurements with a representative drum and {sup 235}U samples. The comparison between calculation and experiment shows a satisfactory agreement for the drum monitor. The final objective of this work is to confirm the reliability of the modeling approach and the industrial feasibility of the method, which will be implemented on the industrial station for the measurement of historical wastes. (authors)

  7. Dimerized Translationally Controlled Tumor Protein-Binding Peptide Ameliorates Atopic Dermatitis in NC/Nga Mice

    Directory of Open Access Journals (Sweden)

    Xing-Hai Jin

    2017-01-01

    Full Text Available Our previous study showed that dimerized translationally controlled tumor protein (dTCTP plays a role in the pathogenesis of allergic diseases, such as asthma and allergic rhinitis. A 7-mer peptide, called dTCTP-binding peptide 2 (dTBP2, binds to dTCTP and inhibits its cytokine-like effects. We therefore examined the protective effects of dTBP2 in house dust mite-induced atopic dermatitis (AD-like skin lesions in Nishiki-nezumi Cinnamon/Nagoya (NC/Nga mice. We found that topical administration of dTBP2 significantly reduced the AD-like skin lesions formation and mast cell infiltration in NC/Nga mice, similarly to the response seen in the Protopic (tacrolimus-treated group. Treatment with dTBP2 also decreased the serum levels of IgE and reduced IL-17A content in skin lesions and inhibited the expression of mRNAs of interleukin IL-4, IL-5, IL-6, IL-13, macrophage-derived chemokine (MDC, thymus and activation-regulated chemokine (TARC and thymic stromal lymphopoietin (TSLP. These findings indicate that dTBP2 not only inhibits the release of Th2 cytokine but also suppresses the production of proinflammatory cytokines in AD-like skin lesions in NC/Nga mice, by inhibiting TCTP dimer, in allergic responses. Therefore, dTCTP is a therapeutic target for AD and dTBP2 appears to have a potential role in the treatment of AD.

  8. Eikonal gluon bremsstrahlung at finite N_c beyond two loops

    CERN Document Server

    Delenda, Yazid

    2015-01-01

    We present a general formalism for computing the matrix-element squared for the emission of soft energy-ordered gluons beyond two loops in QCD perturbation theory at finite $N_c$. Our formalism is valid in the eikonal approximation. A Mathematica program has been developed for the automated calculation of all real/virtual eikonal squared amplitudes needed at a given loop order. For the purpose of illustration we show the explicit forms of the eikonal squared amplitudes up to the fifth-loop order. In the large-$N_c$ limit our results coincide with those previously reported in literature.

  9. Conformal invariance and QCD Pomeron vertices in the $1/N_{c}$ limit

    CERN Document Server

    Janik, R A

    1999-01-01

    Using the dipole framework for QCD at small x in the 1/N_c limit, we derive the expression of the 1 -> p dipole multiplicity density in momentum space. This gives an analytical expression for the 1 -> p QCD Pomeron amplitudes in terms of one-loop integration of effective vertices in transverse momentum. Conformal invariance and a Hilbert space construction for dipole correlation functions are the main tools of the derivation. Relations with conformal field theories in the classical limit are discussed.

  10. The twist-3 parton distribution function e(x) in large-Nc chiral theory

    CERN Document Server

    Cebulla, C; Schweitzer, P; Urbano, D

    2007-01-01

    The chirally-odd twist-3 parton distribution function e(x) of the nucleon is studied in the large-Nc limit in the framework of the chiral quark-soliton model. It is demonstrated that in spite of properties not shared by other distribution functions, namely the appearance of a delta(x)-singularity and quadratic divergences in e(x), an equally reliable calculation is possible. Among the most remarkable results obtained in this work is the fact that the coefficient of the delta(x)-singularity can be computed exactly in this model, avoiding involved numerics. Our results complete existing studies in literature.

  11. Developing the Navy’s NC Flying Boats: Transforming Aeronautical Engineering for the First Transatlantic Flight

    Science.gov (United States)

    2011-12-01

    ft. Max Gross Weight 28,0001b Cruising Speed 84kts Range 1,278 nm Crew 6 Engines (4) 400 hp Liberty L-12 Figure 7. The NC flying boat. In...of the hull. The keel of the hull is built up from spruce while the bottom planking is laid up from two plies of cedar separated by a waterproofing...pilots could remain below decks and out of the weather if desired. The aircraft commander even had enough space to lie down on the planking that made up

  12. The NC11 domain of human collagen XVI induces vasculogenic mimicry in oral squamous cell carcinoma cells.

    Science.gov (United States)

    Bedal, Konstanze B; Grässel, Susanne; Spanier, Gerrit; Reichert, Torsten E; Bauer, Richard J

    2015-11-01

    Collagen XVI, a fibril-associated collagen with interrupted triple helix (FACIT) collagen, is involved in oral squamous cell carcinoma (OSCC) and glioblastoma progression. The NC11 domain of collagen XVI has been described previously with a strong implication in physiological processes. We detected the non-collagenous (NC) 11-domain in supernatants of OSCC cells after recombinant expression of full-length collagen XVI and in sera from OSCC patients and healthy individuals. Stable expression of NC11-green fluorescent protein (GFP) fusion protein in OSCC cells initiated proliferation control and block of anchorage-independent growth. Moreover, the NC11 domain triggered the generation of tubular-like net structures on laminin-rich matrix in contrast to mock-GFP control cells and cells expressing full-length collagen XVI. Taqman® quantitative PCR and diaminobenzidine staining in 2D- and 3D cell culture revealed a significantly increased gene and protein expression of VEGFR1, VEGFR2 and uPAR in recombinant NC11-GFP-expressing cells. Specific VEGF receptor inhibition with Axitinib or fetal calf serum heat inactivation prevented formation of tubular-like net structures. Accordantly, NC11-GFP coated culture slides led to an increase of focal adhesion contact formation and the upregulation of VEGFR1 and uPAR in three different non-transfected OSCC cell lines. In summary, we suggest that the NC11 domain of collagen XVI is a potential biomarker for OSCC and triggers vasculogenic mimicry via upregulation of endothelial receptors VEGFR1, VEGFR2 and uPAR in 2D- and 3D OSCC cell culture conditions.

  13. Measurement of one and two bond N-C couplings in large proteins by TROSY-based J-modulation experiments.

    Science.gov (United States)

    Liu, Yizhou; Prestegard, James H

    2009-09-01

    Residual dipolar couplings (RDCs) between NC' and NC(alpha) atoms in polypeptide backbones of proteins contain information on the orientation of bond vectors that is complementary to that contained in NH RDCs. The (1)J(NC)(alpha) and (2)J(NC)(alpha) scalar couplings between these atoms also display a Karplus relation with the backbone torsion angles and report on secondary structure. However, these N-C couplings tend to be small and they are frequently unresolvable in frequency domain spectra having the broad lines characteristic of large proteins. Here a TROSY-based J-modulated approach for the measurement of small (15)N-(13)C couplings in large proteins is described. The cross-correlation interference effects inherent in TROSY methods improve resolution and signal to noise ratios for large proteins, and the use of J-modulation to encode couplings eliminates the need to remove frequency distortions from overlapping peaks during data analysis. The utility of the method is demonstrated by measurement of (1)J(NC'), (1)J(NC)(alpha) , and (2)J(NC)(alpha) scalar couplings and (1)D(NC') and D(NC)(alpha) residual dipolar couplings for the myristoylated yeast ARF1.GTPgammas protein bound to small lipid bicelles, a system with an effective molecule weight of approximately 70kDa.

  14. The baryon axial current in large $N_c$ chiral perturbation theory

    CERN Document Server

    Hernandez-Ruiz, Maria A

    2014-01-01

    In this thesis we calculate the baryon axial current within the combined framework of the $1/N_c$ expansion and chiral perturbation theory, where $N_c$ is the number of colors. This calculation shall consider Feynman diagrams to order of one-loop, octet and decuplet intermediaries states. We obtain corrections due to one-loop and perturbative SU(3) symmetry breaking. The first corrections come from Feynman diagrams, then talk about a broken chiral symmetry in the implicit limit $m_q \\rightarrow 0$, where $m_q$ is the quark mass and the second corrections are obtained by ignoring isospin breaking and in that case the SU(3) symmetry breaking a first-order perturbation is included, leading an explicit break symmetry. The matrix elements of the spatial components of the axial operator between the states of the spin flavor symmetry, give the typical values of the axial vector coupling. For the baryon octet, links axial vector are $g_A$, just as they are defined in experiments of baryon semileptonic decays, where $...

  15. Effect of frictions on cross section quality of thin-walled tube NC bending

    Institute of Scientific and Technical Information of China (English)

    YANG He; GU Rui-jie; ZHAN Mei; LI Heng

    2006-01-01

    The effect of frictions between dies and tube on the cross section quality of thin-walled tube numerical controlled(NC) bending was studied by numerical simulation method, combined with theoretical analysis and experiment. The results show that the frictions between mandrel, wiper, pressure die, bending die and tube have a significant and complicate effect on the section quality of thin-walled tube NC bending. To improve the section quality, frictions between mandrel, wiper and tube should be decreased, but the frictions between the pressure die, bending die and tube increase. The effect on the section distortion is more significant from mandrel, wiper, pressure die to bending die and the effect on the wall thinning more significant from mandrel, pressure die, wiper, to bending die. The effects of frictions between all dies and tube on wall thinning are smaller than their effects on section distortion.Mandrel and wiper should be lubricated well and drawing oil is used to lubricate them in actual production. The frictions between pressure die, bending die and tube should be increased and the dry friction is used between pressure die, bending die and tube in actual production.

  16. Topical Application of Eupatilin Ameliorates Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

    Science.gov (United States)

    Lee, Ji Hyun; Lee, Ye Jin; Lee, Jun Young

    2017-01-01

    Background Atopic dermatitis (AD) is an inflammatory skin disorder with severe pruritus. Despite advancements in medicine, therapeutic treatments for AD are still limited. Eupatilin (5,7-dihydroxy-30,40,6-trimethoxyflavone) is one of the lipophilic flavonoids from Artemisia umbelliformis Lam. and Artemisia genipi Weber. Objective Although it has been reported to act a role in improving inflammation, its action on AD is uncertain. In this study, we examined the role of eupatilin on AD-like skin lesions in NC/Nga mice. Methods 2,4-dinitrochlorobenzene was repeatedly applied to the ear of NC/Nga mice to produce AD-like skin lesions. Eupatilin (1%, once a day for 5 consecutive days/week) was applied topically for four weeks for the evaluation of its therapeutic effects. Results 1% eupatilin cream significantly reduced the clinical severity score of AD-like lesions, compared to the vehicle (p<0.005). A histopathological analysis revealed that 1% eupatilin cream significantly decreased the mast cell infiltration as well as inflammatory cell infiltration, compared to the vehicle (p<0.005). We showed that 1% eupatilin cream significantly reduced the expression of thymic stromal lymphopoietin, tumor necrosis factor-α, interleukin-4, and interleukin-19, but not interferon-γ, compared to the vehicle (p<0.005). Conclusion Considering the therapeutic reaction of eupatilin on AD-like lesions as in this study, the substance has a promising to be an adjuvant topical agent for the control of AD.

  17. Spin-flavor structure of chiral-odd generalized parton distributions in the large-Nc limit

    Science.gov (United States)

    Schweitzer, P.; Weiss, C.

    2016-10-01

    We study the spin-flavor structure of the nucleon's chiral-odd generalized parton distributions (transversity GPDs) in the large-Nc limit of QCD. In contrast to the chiral-even case, only three combinations of the four chiral-odd GPDs are nonzero in the leading order of the 1 /Nc expansion: E¯T=ET+2 H˜T,HT , and E˜T. The degeneracy is explained by the absence of spin-orbit interactions correlating the transverse momentum transfer with the transverse quark spin. It can also be deduced from the natural Nc scaling of the quark-nucleon helicity amplitudes associated with the GPDs. In the GPD E¯T the flavor-singlet component u +d is leading in the 1 /Nc expansion, while in HT and E˜T it is the flavor-nonsinglet components u -d . The large-Nc relations are consistent with the spin-flavor structure extracted from hard exclusive π0 and η electroproduction data, if it is assumed that the processes are mediated by twist-3 amplitudes involving the chiral-odd GPDs and the chiral-odd pseudoscalar meson distribution amplitudes.

  18. Prediction of the Spectroscopic Parameters of New Iron Compounds: Hydride of Iron Cyanide/Isocyanide, HFeCN/HFeNC

    Science.gov (United States)

    Redondo, Pilar; Barrientos, Carmen; Largo, Antonio

    2016-09-01

    Iron is the most abundant transition metal in space. Its abundance is similar to that of magnesium, and until today only, FeO and FeCN have been detected. However, magnesium-bearing compounds such as MgCN, MgNC, and HMgNC are found in IRC+10216. It seems that the hydrides of iron cyanide/isocyanide could be good candidates to be present in space. In the present work we carried out a characterization of the different minima on the quintet and triplet [C, Fe, H, N] potential energy surfaces, employing several theoretical approaches. The most stable isomers are predicted to be hydride of iron cyanide HFeCN, and isocyanide HFeNC, in their 5Δ states. Both isomers are found to be quasi-isoenergetics. The HFeNC isomer is predicted to lie about 0.5 kcal/mol below HFeCN. The barrier for the interconversion process is estimated to be around 6.0 kcal/mol, making this process unfeasible under low temperature conditions, such as those in the interstellar medium. Therefore, both HFeCN and HFeNC could be candidates for their detection. We report geometrical parameters, vibrational frequencies, and rotational constants that could help with their experimental characterization.

  19. Subcloning and expression of the NcSRS2 gene fragment of Neospora caninum%新孢子虫NcSRS2基因的亚克隆和表达

    Institute of Scientific and Technical Information of China (English)

    余劲术; 刘群; 汪明

    2006-01-01

    本研究根据NcSRS2基因序列设计合成一对引物,将上、下游引物分别引入EcoRI,XhoI酶切位点,用PCR技术从pGEX-NcSRS2重组质粒扩增截去N端疏水氨基酸序列NcSRS2的基因片段(以下称dNcSRS2),插入到pGEX-6p-1质粒的多克隆位点,转化大肠杆菌BL21感受态细胞,于氨苄阳性LB培养平板上筛选阳性克隆,酶切及PCR鉴定;经IPTG诱导在E.coli中表达,用SDS-PAGE和免疫印迹分析表达产物并纯化.结果表明,新孢子虫dNcSRS2基因体外扩增产物与预期值相符,约1041bp;所构建pGEX-dNcSRS2重组质粒经双酶切与PCR鉴定,与预期结果一致;SDS-PAGE和免疫印迹显示,表达融合蛋白的分子量约为62.6 kD,表达效率为32.3%,该蛋白具有特异的免疫反应性,为新孢子虫病诊断试剂盒的研制和疫苗的研制奠定了基础.

  20. Study of geometric errors detection method for NC machine tools based on non-contact circular track

    Science.gov (United States)

    Yan, Kejun; Liu, Jun; Gao, Feng; Wang, Huan

    2008-12-01

    This paper presents a non-contact measuring method of geometric errors for NC machine tools based on circular track testing method. Let the machine spindle move along a circular path, the position error of every tested position in the circle can be obtained using two laser interferometers. With a volumetric error model, the 12 components of geometric error apart from angular error components can be derived. It has characteristics of wide detection range and high precision. Being obtained geometric errors respectively, it is of great significance for the error compensation of NC machine tools. This method has been tested on a MCV-510 NC machine tool. The experiment result has been proved to be feasible for this method.

  1. 2D-DOA estimation of noncircular signals for uniform rectangular array via NC-PARAFAC method

    Science.gov (United States)

    Zhang, Licen; Lv, Weihua; Zhang, Xiaofei; Li, Shu

    2016-11-01

    In this paper, we propose a two-dimensional direction of arrival (2D-DOA) estimation algorithm for uniform rectangular array via noncircular-parallel factor (NC-PARAFAC) method. Compared to the conventional parallel factor (PARAFAC) algorithm, the proposed algorithm exploits the property of noncircular signals to double the array aperture. Therefore, the angle estimation performance of the proposed algorithm is better than the conventional PARAFAC method. The proposed algorithm achieves automatically paired two-dimensional angle estimates, and has better 2D-DOA estimation performance than some conventional algorithms, which include estimation of signal parameters via rotational invariance technique (ESPRIT), propagator method (PM), PARAFAC algorithm, noncircular-ESPRIT (NC-ESPRIT) and noncircular-PM (NC-PM). We also derive the Cramér-Rao bound for the 2D-DOA estimation of noncircular signals with uniform rectangular array. Simulation results verify the effectiveness and improvement of the proposed algorithm.

  2. 叠氮侧链支化NC的合成和表征%Synthesis and Properties of Azido-sidechain Branched NC

    Institute of Scientific and Technical Information of China (English)

    杨斐霏; 邵自强; 王飞俊; 王文俊; 张有德; 王慧庆

    2011-01-01

    In order to break the energy limitation of nitrocellulose(NC) and improve its low-temperature mechanical properties by decreasing the glass transition temperature, NC with azide side chains called PA-IPDI branching NC was synthesised. Via isophorone diisocyanate (IPDI) first reacted with residual hydroxyl on NC, and then reacted with the introduced 2,2-bis azido methyl 1 ,3-propanediol (PA). Its molecular structure, energy performance, thermal stability and dynamic mechanical properties of PA-IPDI branching NC were studied by IR, elemental analysis, TG, DSC and DMA, respectively. The results show that the released heat per mass unit of modified NC of 1466 J · G"' is nearly two times more than unmodified NC with 11. 75% N. The calculated value of heat of detonation of modified NC ( 4434 kJ · Kg-1) is higher than that of 1 · NC (4152 kJ · Kg-1). The glass transition temperature of modified NC (117.3 ℃) is lower than that of unmodified NC with 11. 75% N (140. 2 ℃), the tensile modulus of modified NC is higher than that of unmodified NC within ± 60 ℃. It is suggested that PA-IPDI modified NC is an excellent substitute of NC.%为突破硝化纤维素(NC)的能量限制,降低玻璃化温度以提高NC的低温力学性能,通过异佛尔酮二异氰酸酯(IPDI)与NC上残余的羟基反应,然后与2,2-二叠氮甲基-1,3-丙二醇(PA)反应,合成了一种叠氮侧链NC,称为支化NC的叠氮侧链NC(即PA-IPDI改性NC).用红外(IR)、元素分析、热重分析(TG)、差示扫描量热分析(DSC)和动态力学分析(DMA)等方法研究了产物的分子结构、能量性能、热稳定性及动态力学性能.结果表明,改性NC单位质量的放热量接近改性前NC(含氮量11.75%)的2倍,计算爆热为4434 kJ·kg-1,超过1#NC(4152 kJ·kg-1)的水平,改性后玻璃化转变温度(117.3 ℃)低于改性前NC(140.2℃),并且在±60℃范围内,改性NC的抗拉模量也高于改性前NC,认为PA-IPDI改性NC是一种性能优良的NC替代品.

  3. Silencing nc886, a Non-Coding RNA, Induces Apoptosis of Human Endometrial Cancer Cells-1A In Vitro

    Science.gov (United States)

    Hu, Zhuoying; Zhang, Hongyu; Tang, Liangdan; Lou, Meng; Geng, Yanqing

    2017-01-01

    Background The role that nc886, a non-coding microRNA, plays in human endometrial cancer is unknown. The present study aimed to describe the functional role of nc886 in human endometrial cancer-1A (HEC-1A) cell line, which may provide another target for human endometrial cancer treatment. Material/Methods The expression levels of nv886 in normal human endometrial tissue and the early phase and late phase of human endometrial cancer tissues were determined and compared by fluorescence in situ hybridization (FISH). Small interference RNA (siRNA) was used to inhibit nc886, and cell proliferation was evaluated with the MTT test. mRNA levels of PKR, NF-κB, vascular endothelial growth factor (VEGF), and caspase-3 were determined against glyceraldehyde 3-phosphate dehydrogenase (GAPDH between the HEC-1A control group and the silenced group (nc886 silenced with siRNA) by real-time reverse transcription polymerase chain reaction (RT-PCR). The protein levels of PKR (total and phosphorylated form), NF-κB, VEGF, and caspase-3 were determined against GAPDH by Western blotting, and cell apoptosis was determined by flow cytometry. Results Our results indicated that a higher level of nc886 was expressed in the late phase of human endometrial cancer tissue, less than in the early phase but still higher than in normal human endometrial tissue. After nc886 was silenced, protein levels of p-PKR (phosphorylated PKR) and caspase-3 were increased, whereas NF-κB and VEGF were decreased. Conclusions The rate of apoptosis in the silenced group was increased and the rate of cell proliferation was slower in comparison to the control. PMID:28298621

  4. Large N$_{c}$ universality of the baryon Isgur-Wise form factor the group theoretical approach

    CERN Document Server

    Chow, C K

    1996-01-01

    In a previous article, it has been proved under the framework of chiral soliton model that the same Isgur--Wise form factor describes the semileptonic \\Lambda_b\\to\\Lambda_c and \\Sigma^{(*)}_b\\to\\Sigma^{(* )}_c decays in the large N_c limit. It is shown here that this result is in fact independent of the chiral soliton model and is solely the consequence of the spin-flavor SU(4) symmetry which arises in the baryon sector in the large N_c limit.

  5. Review of the Development of NC Woodworking Machinery%数控木工机床发展综述

    Institute of Scientific and Technical Information of China (English)

    汪子卜; 朱兴微; 何盛; 卫佩行

    2012-01-01

      The development of NC technology in wood processing industry is stated, a five-axis NC machine to be developed is introduced and the development prospect of CN technology in the woodworking machinery field is analyzed.%  阐述了数控技术在木材加工行业的发展,介绍了目前亟待发展的五轴数控机床,分析了数控技术在木材加工机械领域的发展前景。

  6. 数控机床产业强势增长%Robust growth of NC machine tool industry

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ The machine tool industry is an industry which provides production equipment for the equipment manufacturing industry, and the machine tool is the parent machine for equipment manufacturing, playing a key part in the industry.The equipment manufacturing industry, for example, the automobile industry, uses more than 60% of its fixed asset investment in the purchase of machine tools.The numerical control (NC)machine tool, as a mainstream product of the machine tool sector, has become a key piece of equipment for achieving modernisation of equipment manufacturing.It is the realistic requirement to speed up development of NC machine production for the development of China's equipment manufacturing industry.

  7. INTERFERENCE-FREE TOOL POSTURE GENERATION FOR 5-AXIS NC MILLING FREE-FORM SURFACES WITH CYLINDRICAL MILL

    Institute of Scientific and Technical Information of China (English)

    Chen Liping; Chen Yan; Hu Dejin

    2004-01-01

    The 5-axis NC machining offers the potential of efficient and accurate machining. However, the present CAM system for 5-axis control is still an unsolved problem due to interference between tool and surrounding objects. A new method is presented. There are two steps in this procedure. First, it detects the interference by calculating the shortest distance between the tool-axis and the surrounding surfaces. Then upon the maximum gouging, the interference-free tool posture for 5-axis NC cylindrical milling free-form surfaces is obtained by adjusting tool. The validity of the proposed method has been confirmed by machining an impeller.

  8. N=2 supersymmetric QCD and integrable spin chains rational case N$_{f}<$2N$_{c}$

    CERN Document Server

    Gorsky, A S; Mironov, A E; Morozov, A

    1996-01-01

    The form of the spectral curve for 4d N=2 supersymmetric Yang-Mills theory with matter fields in the fundamental representation of the gauge group suggests that its 1d integrable counterpart should be looked for among (inhomogeneous) sl(2) spin chains with the length of the chain being equal to the number of colours N_c. For N_f < 2N_c the relevant spin chain is the simplest XXX-model, and this identification is in agreement with the known results in Seiberg-Witten theory.

  9. Wholly smoothing cutter orientations for five-axis NC machining based on cutter contact point mesh

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Cutting forces with respect to different cutter orientations are analyzed for five-axis NC machining of a ball-end cutter.A measure is then defined to quantify the effects of cutter orientation variation.According to the measure,a novel model and algorithm are proposed to wholly optimize cutter orientations based on a cutter contact(CC) point mesh.The method has two advantages.One is that the cutter orientation smoothnesses along the feed direction and pick-feed direction are both wholly optimized.The other is that only the accessibility cones of mesh points are required to compute and the computation efficiency is improved.These advantages are shown by simulating the machining efficiency,the stability of feed velocities and the smoothness of cutting force.A computational example and a cutting experiment are finally given to illustrate the validity of the proposed method.

  10. Kinematic modelling of a 3-axis NC machine tool in linear and circular interpolation

    CERN Document Server

    Pessoles, Xavier; Rubio, Walter; 10.1007/s00170-009-2236-z

    2010-01-01

    Machining time is a major performance criterion when it comes to high-speed machining. CAM software can help in estimating that time for a given strategy. But in practice, CAM-programmed feed rates are rarely achieved, especially where complex surface finishing is concerned. This means that machining time forecasts are often more than one step removed from reality. The reason behind this is that CAM routines do not take either the dynamic performances of the machines or their specific machining tolerances into account. The present article seeks to improve simulation of high-speed NC machine dynamic behaviour and machining time prediction, offering two models. The first contributes through enhanced simulation of three-axis paths in linear and circular interpolation, taking high-speed machine accelerations and jerks into account. The second model allows transition passages between blocks to be integrated in the simulation by adding in a polynomial transition path that caters for the true machining environment t...

  11. Quantitative multichannel NC-AFM data analysis of graphene growth on SiC(0001

    Directory of Open Access Journals (Sweden)

    Christian Held

    2012-02-01

    Full Text Available Noncontact atomic force microscopy provides access to several complementary signals, such as topography, damping, and contact potential. The traditional presentation of such data sets in adjacent figures or in colour-coded pseudo-three-dimensional plots gives only a qualitative impression. We introduce two-dimensional histograms for the representation of multichannel NC-AFM data sets in a quantitative fashion. Presentation and analysis are exemplified for topography and contact-potential data for graphene grown epitaxially on 6H-SiC(0001, as recorded by Kelvin probe force microscopy in ultrahigh vacuum. Sample preparations by thermal decomposition in ultrahigh vacuum and in an argon atmosphere are compared and the respective growth mechanisms discussed.

  12. Vector meson masses in two-dimensional SU(NC) lattice gauge theory with massive quarks

    Institute of Scientific and Technical Information of China (English)

    JIANG Jun-Qin

    2008-01-01

    Using an improved lattice Hamiltonian with massive Wilson quarks a variational method is applied to study the dependence of the vector meson mass Mv on the quark mass m and the Wilson parameter r in in the scaling window 1 ≤ 1/g2 ≤ 2, Mv/g is approximately linear in m, but Mv/g obviously does not depend on r (this differs from the quark condensate). Particularly for m → 0 our numerical results agree very well with Bhattacharya's analytical strong coupling result in the continuum, and the value of ((e)Mv/(e)m) |mm=0 in two-dimensional SU(NC) lattice gauge theory is very close to that in Schwinger model.

  13. Plastic deformation analysis and forming quality prediction of tube NC bending

    Institute of Scientific and Technical Information of China (English)

    Lu Shiqiang; Fang Jun; Wang Kelu

    2016-01-01

    Plane strain assumption and exponent hardening law are used to investigate the plastic deformation in tube bending. Some theoretical formulae including stress, curvature radius of neu-tral layer, angle of neutral layer deviation, bending moment, wall thickness variation and cross-section distortion, are developed to explain the phenomena in tube bending and their magnitudes are also determined. During unloading process, the springback angle is deduced using the virtual work principle, and springback radius is also given according to the length of the neutral layer which remains unchanged before and after springback. The theoretical formulae are validated by the experimental results or the validated simulation results in literature, which can be used to quickly predict the forming quality of tube numerical control (NC) bending.

  14. Negative parity baryons in the $1/N_c$ expansion: the three towers of states revisited

    CERN Document Server

    Matagne, N

    2012-01-01

    We discuss the compatibility between the quark-shell picture and the meson-nucleon scattering picture in large $N_c$ QCD for mixed symmetric $\\ell$ = 1 states previously analyzed by using a simple Hamiltonian including operators up to order $\\mathcal{O}(N^0_c)$ defined in the standard ground state symmetric core + excited quark procedure. Here we introduce a Hamiltonian of order $\\mathcal{O}(N^0_c)$ defined in a new approach where the separation of the system into two parts is not required. Three degenerate sets of states (towers) with the same quantum numbers as in the scattering picture and in the standard procedure are obtained. Thus the 0 is equally achieved. The eigenvalues of the presently chosen Hamiltonian also have simple analytic expressions, depending linearly on the three dynamical coefficients entering the Hamiltonian. This reinforces the validity of the new approach which had already 0 described excited negative parity baryons in a large energy range.

  15. Measurement of airborne fission products in Chapel Hill, NC, USA from the Fukushima I reactor accident

    CERN Document Server

    MacMullin, S; Green, M P; Henning, R; Holmes, R; Vorren, K; Wilkerson, J F

    2011-01-01

    We present measurements of airborne fission products in Chapel Hill, NC, USA, from 62 days following the March 11, 2011, accident at the Fukushima I Nuclear Power Plant. Airborne particle samples were collected daily in air filters and radio-assayed with two high-purity germanium (HPGe) detectors. The fission products I-131 and Cs-137 were measured with maximum activities of 4.2 +/- 0.6 mBq/m^2 and 0.42 +/- 0.07 mBq/m^2 respectively. Additional activity from I-131, I-132, Cs-134, Cs-136, Cs-137 and Te-132 were measured in the same air filters using a low-background HPGe detector at the Kimballton Underground Research Facility (KURF).

  16. Time-reversal-invariance-violating nucleon-nucleon potential in the 1/N_c expansion

    CERN Document Server

    Samart, Daris; Schindler, Matthias R; Phillips, Daniel R

    2016-01-01

    We apply the large-$N_c$ expansion to the time-reversal-invariance-violating (TV) nucleon-nucleon potential. The operator structures contributing to next-to-next-to-leading order in the large-$N_c$ counting are constructed. For the TV and parity-violating case we find a single operator structure at leading order. The TV but parity-conserving potential contains two leading-order terms, which however are suppressed by 1/$N_c$ compared to the parity-violating potential. Comparison with phenomenological potentials, including the chiral EFT potential in the TV parity-violating case, leads to large-$N_c$ scaling relations for TV meson-nucleon and nucleon-nucleon couplings.

  17. l585nc.m77t - MGD77 data file for Geophysical data from field activity L-5-85-NC in Northern California from 08/10/1985 to 08/31/1985

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetics data along with DGPS navigation data was collected as part of field activity L-5-85-NC in Northern California from 08/10/1985...

  18. l585nc.m77t - MGD77 data file for Geophysical data from field activity L-5-85-NC in Northern California from 08/10/1985 to 08/31/1985

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetics data along with DGPS navigation data was collected as part of field activity L-5-85-NC in Northern California from 08/10/1985 to...

  19. l785nc.m77t - MGD77 data file for Geophysical data from field activity l-7-85-nc in Southern Pacific from 12/28/1983 to 01/03/1984

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with transit satellite navigation data was collected as part of field activity L-7-85-NC in Northern California from 09/23/1985 to...

  20. Construction of an Eukaryotic Expression Plasmid for NcSRS2 Gene of Neospora caninum%犬新孢子虫NcSRS2基因真核表达质粒的构建

    Institute of Scientific and Technical Information of China (English)

    赵占中; 刘群; 汪明

    2005-01-01

    根据犬新孢子虫NcSRS2基因序列,设计了1对含有Kozak序列、PstⅠ和XbaⅠ酶切位点的引物,以含有NcSRS2基因的质粒P43为模板,经PCR扩增获得NcSRS2 ORF基因片段,用PstⅠ和XbaⅠ双酶切该片段,回收得到含有以上2个酶切位点黏端的NcSR2 ORF基因,将此基因片段克隆至相同酶切回收后的pcDNA3.1(+)真核表达载体中,获得重组质粒pcNCSRS2.经PCR鉴定、限制性内切酶分析和克隆片段序列测定、比较,证实了重组质粒的正确性.

  1. Construction of Prokaryotic Expression Plasmid of NcSRS2 Gene of Neospora caninum%犬新孢子虫NcSRS2基因原核表达质粒的构建

    Institute of Scientific and Technical Information of China (English)

    丁德; 梁晚枫; 田野; 田万年; 贾立军; 张守发

    2008-01-01

    根据已发表的犬新孢子虫NcSRS2基因序列,设计1对含有EcoRⅠ和NotⅠ酶切位点的引物.以提取犬新孢子虫虫体基因组DNA为模板,应用PCR扩增获得NcSRS2 ORF基因片段,将此基因片段克隆到pMD18-T Simple载体上,用EcoRⅠ和NotⅠ双酶切该片段,回收得到含有两个酶切位点黏端的NcSRS2 ORF基因,将此基因片段克隆至相同酶切回收后的PGEM-4T-2原核表达载体中,获得重组质粒pGEX-NcSRS2,经PCR鉴定,限制性内切酶分析和克隆片段序列测定比较,证实了重组质粒的正确性.

  2. l1381nc.m77t - MGD77 data file for Geophysical data from field activity L-13-81-NC in Northern California from 10/09/1981 to 10/23/1981

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with DGPS navigation data was collected as part of field activity L-13-81-NC in Northern California from 10/09/1981 to 10/23/1981,...

  3. l182nc.m77t - MGD77 data file for Geophysical data from field activity L-1-82-NC in Northern California from 02/02/1982 to 02/03/1982

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetic data along with DGPS navigation data was collected as part of field activity L-1-82-NC in Northern California from 02/02/1982 to...

  4. l685nc.m77t - MGD77 data file for Geophysical data from field activity L-6-85-NC in Northern California from 09/03/1985 to 09/20/1985

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetics data along with DGPS navigation data was collected as part of field activity L-6-85-NC in Northern California from 09/03/1985 to...

  5. l385nc.m77t - MGD77 data file for Geophysical data from field activity L-3-85-NC in Northern California from 07/15/1985 to 07/17/1985

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with DGPS navigation data was collected as part of field activity L-3-85-NC in Northern California from 07/15/1985 to 07/17/1985,...

  6. l285nc.m77t - MGD77 data file for Geophysical data from field activity L-2-85-NC in Northern California from 04/03/1985 to 04/04/1985

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with DGPS navigation data was collected as part of field activity L-2-85-NC in Northern California from 04/03/1985 to 04/04/1985,...

  7. f384nc.m77t - MGD77 data file for Geophysical data for field activity F-3-84-NC in Northern California from 06/15/1984 to 07/08/1984

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetics data along with DGPS navigation data was collected as part of field activity F-3-84-NC in Northern California from 06/15/1984...

  8. {sup 99m}Tc-NC100668, a new tracer for imaging venous thromboemboli: pre-clinical biodistribution and incorporation into plasma clots in vivo and in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, David [Grove Centre, Research and Development, GE Healthcare Bio-Sciences, Little Chalfont (United Kingdom); Uppsala University Hospital, Institution of Oncology, Radiology and Clinical Immunology, Section of Radiology, Uppsala (Sweden); Lewis, Joanne; Battle, Mark; Lear, Rochelle; Farrar, Gill; Barnett, D.J.; Godden, Vanessa; Oliveira, Alexandra; Coombes, Catherine [Grove Centre, Research and Development, GE Healthcare Bio-Sciences, Little Chalfont (United Kingdom); Ahlstroem, Haakan [Uppsala University Hospital, Institution of Oncology, Radiology and Clinical Immunology, Section of Radiology, Uppsala (Sweden)

    2006-11-15

    {sup 99m}Tc-NC100668 is a new radiotracer being developed to aid the diagnosis of thromboembolism. The structure of NC100668 is similar to a region of human {alpha}{sub 2}-antiplasmin, which is a substrate for factor XIIIa (FXIIIa). The purpose of this study was to confirm the uptake of {sup 99m}Tc-NC100668 into forming plasma clot and to establish the biodistribution of {sup 99m}Tc-NC100668 in Wistar rats. The in vitro plasma clot uptake of {sup 99m}Tc-NC100668 and other compounds with known affinities to FXIIIa was measured using a plasma clot assay. The biodistribution and blood clot uptake of radioactivity of {sup 99m}Tc-NC100668 in normal Wistar rats and those bearing experimentally induced deep vein thrombi were investigated. The in vitro uptake of {sup 99m}Tc-NC100668 was greater than that for [{sup 14}C]dansyl cadaverine, a known substrate of FXIIIa in the plasma clot assay. The biodistribution of {sup 99m}Tc-NC100668 in male and female Wistar rats up to 24 h p.i. showed that radioactivity was rapidly excreted, predominantly into the urine, with very little background tissue retention. In vivo the uptake and retention of {sup 99m}Tc-NC100668 into the blood clot was greater than could be accounted for by non-specific accumulation of the radiotracer within the blood clot. {sup 99m}Tc-NC100668 was retained by plasma clots in vitro and blood clots in vivo. No significant tissue retention which could interfere with the ability to image thrombi in vivo was observed. This evidence suggests that {sup 99m}Tc-NC100668 might be useful in the detection of thromboembolism. (orig.)

  9. Immunity assay of the NcSAG1 subunit vaccine against bovine Neospora caninum%牛新孢子虫NcSAG1基因工程亚单位疫苗的免疫试验

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发; 栾杨; 焦石

    2010-01-01

    为了解新孢子虫NcSAG1表面蛋白基因工程亚单位疫苗对实验动物的免疫效果,本试验提取延边黄牛新孢子虫野毒株基因组DNA,用PCR技术扩增新孢子虫NcSAG1表面蛋白基因,并在大肠杆菌中进行原核表达,将Western-blot鉴定具有免疫活性的重组蛋白与弗氏佐剂混合制备NcSAG1基因工程亚单位疫苗,免疫BALB/c小鼠,应用间接ELISA方法测定体液免疫水平,应用流式细胞技术测定细胞免疫水平,以此评价疫苗对实验动物的免疫应答反应.结果显示,制备的NcSAG1基因工程亚单位疫苗免疫BALB/c小鼠后,在三免后第3天时,检测抗体的OD450nm值达0.688;CD4+/CD8+值达3.650,均显著高于重组蛋白免疫组和PBS对照组,说明制备的基因工程亚单位疫苗能够提高实验动物的体液免疫和细胞免疫水平.本试验为牛新孢子虫NcSAG1表面蛋白基因工程亚单位疫苗的深入研究奠定了基础.

  10. 牛新孢子虫NcSRS2基因腺病毒穿梭载体的构建及在293细胞中的表达%Construction of bovine Neospora caninum NcSRS2 adenovirus shuttle vector and expression of NcSRS2 gene in 293 cells

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发; 刘明明

    2012-01-01

    应用PCR技术扩增牛新孢子虫NcSRS2基因,纯化PCR产物后与克隆载体pMD18-T Simple Vector连接,将PCR、酶切鉴定及测序分析正确的pMD-18T-NcSRS2重组质粒进行EcoRⅠ和XbaⅠ双酶切,克隆至相同酶切回收后的腺病毒穿梭载体pCR259中,再将PCR、酶切鉴定正确的pCR259-NcSRS2重组质粒转染293细胞,应用IF-AT和Western-blotting技术检测重组质粒在293细胞中的表达情况。结果显示,扩增的牛新孢子虫NcSRS2基因长度为1 227bp,与GenBank中发表的NcSRS2(AF061249)核苷酸序列同源性为99%,构建的pCR259-NcSRS2重组质粒在293细胞中得到瞬时表达,表达蛋白的相对分子质量为43 000,具有较好的反应原性。本试验为新孢子虫病腺病毒载体疫苗的构建奠定了基础。%In this research,bovine Neospora caninum NcSRS2 gene was amplified by PCR.The purified PCR products were ligated with pMD18-T simple vector.After enzyme digestion and sequence analysis,the correct pMD-18T-NcSRS2 gene was digested by EcoRⅠand XbaⅠ,and cloned into the adenovirus shuttle vector pCR259 which was digested by the same enzymes.The correct pCR259-NcSRS2 recombinant plasmid was transfected into 293 cells.The expression of recombinant plasmid in 293 cells was detected by IFAT and Western-blotting.The result shows that the length of bovine Neospora caninum NcSRS2 gene is 1 227 bp.which has 99% homology with sequence and sequence in GenBank.The pCR259-NcSRS2 recombinant plasmid could transiently express in 293 cells.The molecular weight of the expressed protein which has good reactionogenicity is 43 000.This research laid the foundation for the construction of Neospora caninum vector-adenovirus vaccine

  11. First-principles investigation of quantum transport through an endohedral N@C60 in the Coulomb blockade regime.

    Science.gov (United States)

    Yu, Zhizhou; Chen, Jian; Zhang, Lei; Wang, Jian

    2013-12-11

    We report an investigation of Coulomb blockade transport through an endohedral N@C60 weakly coupled with aluminum leads, employing the first-principles method combined with the Keldysh non-equilibrium Green's function derived from the equation of motion beyond the Hartree-Fock approximation. The differential conductance characteristics of the molecular device are calculated within the Coulomb blockade regime, which shows the Coulomb diamond as observed experimentally. When the gate voltage is less than that of the degeneracy point, there are two peaks in the differential conductance with an excited state induced by the change of the exchange interaction between the spin of C60 and the encapsulated nitrogen atom due to the transition from N@C(1-)(60) to N@C(2-)(60), while for a gate voltage larger than that of the degeneracy point, no excited state is available due to the quenching of exchange energy. As a result, there is only one Coulomb blockade peak in the differential conductance from the electron tunneling through the highest energy level below the Fermi level. Our first-principles results are in good agreement with experimental data obtained by an endohedral N@C60 molecular device.

  12. The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex

    Energy Technology Data Exchange (ETDEWEB)

    Blanc, Guillaume; Duncan, Garry A.; Agarakova, Irina; Borodovsky, Mark; Gurnon, James; Kuo, Alan; Lindquist, Erika; Lucas, Susan; Pangailinan, Jasmyn; Polle, Juergen; Salamov, Asaf; Terry, Astrid; Yamada, Takashi; Dunigan, David D.; Grigoriev, Igor V.; Claverie, Jean-Michel; Etten, James L. Van

    2010-05-06

    Chlorella variabilis NC64A, a unicellular photosynthetic green alga (Trebouxiophyceae), is an intracellular photobiont of Paramecium bursaria and a model system for studying virus/algal interactions. We sequenced its 46-Mb nuclear genome, revealing an expansion of protein families that could have participated in adaptation to symbiosis. NC64A exhibits variations in GC content across its genome that correlate with global expression level, average intron size, and codon usage bias. Although Chlorella species have been assumed to be asexual and nonmotile, the NC64A genome encodes all the known meiosis-specific proteins and a subset of proteins found in flagella. We hypothesize that Chlorella might have retained a flagella-derived structure that could be involved in sexual reproduction. Furthermore, a survey of phytohormone pathways in chlorophyte algae identified algal orthologs of Arabidopsis thaliana genes involved in hormone biosynthesis and signaling, suggesting that these functions were established prior to the evolution of land plants. We show that the ability of Chlorella to produce chitinous cell walls likely resulted from the capture of metabolic genes by horizontal gene transfer from algal viruses, prokaryotes, or fungi. Analysis of the NC64A genome substantially advances our understanding of the green lineage evolution, including the genomic interplay with viruses and symbiosis between eukaryotes.

  13. 76 FR 39155 - R.J. Corman Railroad Property, LLC-Acquisition Exemption-NC Railroad, Inc

    Science.gov (United States)

    2011-07-05

    ... Surface Transportation Board R.J. Corman Railroad Property, LLC--Acquisition Exemption--NC Railroad, Inc R... acquisition transaction is related to the notice of exemption in Docket No. FD 35364, R. J. Corman Railroad Company/Bardstown Line-- Lease and Operation Exemption--R. J. Corman Railroad Property, LLC, in which R....

  14. The Application of the GM (1,1) Metabolism Model to Error Data Processing of NC Machine Tools

    Institute of Scientific and Technical Information of China (English)

    LIAO De-gang; XIONG Xiao-hong

    2003-01-01

    This paper applied the gray system theory to error data processing of NC machine tools ac cording to the characteristic. It presented the gray metabolism model of error data processing. The test method for the model needs less capacity. Practice proved that the method is simple, calculation is easy, and results are exact.

  15. Old nuclear symmetries and large N(c) as long distance symmetries in the two nucleon system

    CERN Document Server

    Arriola, E Ruiz

    2009-01-01

    Wigner and Serber symmetries for the two-nucleon system provide unique examples of long distance symmetries in Nuclear Physics, i.e. symmetries of the meson exchange forces broken only at arbitrarily small distances. We analyze the large Nc picture as a key ingredient to understand these, so far accidental, symmetries from a more fundamental viewpoint. A set of sum rules for NN phase-shifts, NN potentials and coarse grained V_lowk NN potentials can be derived showing Wigner SU(4) and Serber symmetries not to be fully compatible everywhere. The symmetry breaking pattern found from the partial wave analysis data, high quality potentials in coordinate space at long distances and their V_lowk relatives is analyzed on the light of large N(c) contracted SU(4) symmetry. Our results suggest using large Nc potentials as long distance ones for the two-nucleon system where the meson exchange potential picture is justified and known to be consistent with large Nc counting rules. We also show that potentials based on chir...

  16. 33 CFR 334.410 - Albemarle Sound, Pamlico Sound, and adjacent waters, NC; danger zones for naval aircraft operations.

    Science.gov (United States)

    2010-07-01

    ..., and adjacent waters, NC; danger zones for naval aircraft operations. 334.410 Section 334.410 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE...; danger zones for naval aircraft operations. (a) Target areas—(1) North Landing River (Currituck...

  17. Tracking Neospora caninum parasites using chimera monoclonal antibodies against its surface antigen-related sequences (rNcSRS2).

    Science.gov (United States)

    Dong, Jinhua; Otsuki, Takahiro; Kato, Tatsuya; Park, Enoch Y

    2014-03-01

    Neosporosis, an infectious disease of cattle and dogs, causes an abortion in cattle, which has a major damage on the dairy industry worldwide. Tracking of Neospora caninum parasite that is responsible for neosporosis is required for the prevention of this infectious disease. We developed three chimera monoclonal antibodies consist of variable regions of murine antibody and constant regions of human antibody against N. caninum. Recombinant surface antigen-related sequence 2 (rNcSRS2) of N. caninum was expressed in silkworm larvae, and immunized in mice to obtain phage displaying antibody library. Through three rounds of selection, three antibodies, A6, E1 and H3, were isolated and bound to rNcSRS2 with nanomolar to micromolar affinity. In immunofluorescent staining assays, A6 and E1 bound to N. caninum strain Nc-Liv, demonstrating a successful tracking of the parasite. H3 clone bound to rNcSRS2 but not to a truncated protein without glycosylphosphatidylinositol (GPI) anchor domain in the carboxyl terminal. Amino acid sequences of A6 and E1 were similar, but that of H3 differed in the CDR-H1 region, which might be the reason of their difference of affinity. These antibodies are thought to be useful for prevention of cattle from neosporosis.

  18. Two-phase nc-TiN/a-(C,CNx) nanocomposite films: A HRTEM and MC simulation study

    Science.gov (United States)

    Guo, J.; Lu, Y. H.; Hu, X. J.; Shen, Y. G.

    2013-06-01

    The grain growth in two-phase nanocomposite Ti-Cx-Ny thin films grown by reactive close-field unbalanced magnetron sputtering in an Ar-N2 gas mixture with microstructures comprising of nanocrystalline (nc-) Ti(N,C) phase surrounded by amorphous (a-) (C,CNx) phase was investigated by a combination of high-resolution transmission electron microscopy (HRTEM) and Monte Carlo (MC) simulations. The HRTEM results revealed that amorphous-free solid solution Ti(C,N) thin films exhibited polycrystallites with different sizes, orientations and irregular shapes. The grain size varied in the range between several nanometers and several decade nanometers. Further increase of C content (up to ˜19 at.% C) made the amorphous phase wet nanocrystallites, which strongly hindered the growth of nanocrystallites. As a result, more regular Ti(C,N) nanocrystallites with an average size of ˜5 nm were found to be separated by ˜0.5-nm amorphous phases. When C content was further increased (up to ˜48 at.% in this study), thicker amorphous matrices were produced and followed by the formation of smaller sized grains with lognormal distribution. Our MC analysis indicated that with increasing amorphous volume fraction (i.e. increasing C content), the transformation from nc/nc grain boundary (GB)-curvature-driven growth to a/nc GB-curvature-driven growth is directly responsible for the observed grain growth from great inhomogeneity to homogeneity process.

  19. Investigation of the vertical electrical transport in a-Si:H/nc-Si:H superlattice thin films.

    Science.gov (United States)

    Das, Debajyoti; Kar, Debjit

    2015-07-14

    Tuning the size of silicon nano-crystallites (Si-ncs) has been realized simply by controlling the thickness of the nc-Si:H sub-layer (tnc) in the a-Si:H/nc-Si:H superlattice thin films grown by low temperature plasma processing in PE-CVD. The vertical electrical transport phenomena accomplished in superlattice films have been investigated in order to identify their effective utilization in practical device configuration. The reduced size of the Si-ncs at thinner tnc and the associated band gap widening due to quantum confinement effects generates the Coulomb potential barrier at the a-Si/nc-Si interface which in turn obstructs the transport of charge carriers to the allowed energy states in Si-ncs, leading to the Poole-Frenkel tunneling as the prevailing charge transport mechanism in force. The advantages of the conduction process governed by the Poole-Frenkel mechanism are two-fold. The lower barrier height caused by the a-Si:H sub-layer in the superlattice than the silicon oxide sub-layer in conventional structures enhances the conduction current. Moreover, increasing trapped charges in the a-Si:H sub-layer can arbitrarily increase the current conduction. Accordingly, a-Si:H/nc-Si:H superlattice structures could provide superior electrical transport in stacked layer devices e.g., multi-junction all silicon solar cells.

  20. Psych NP-NC: a benchmark graduate nurse practitioner program for meeting the mental health needs in North Carolina.

    Science.gov (United States)

    Soltis-Jarrett, Victoria

    2011-01-01

    UNC-Chapel Hill's Psych NP-NC program prepares clinically and culturally proficient nurse practitioners to provide psychiatric and mental health care in North Carolina areas that are medically underserved and have a greater number of health disparities. This article reviews the program and the role of its graduates and makes policy recommendations for improving mental health care in the state.

  1. Skill for machining worm screw with NC lathe%数控车床上蜗杆的加工技巧

    Institute of Scientific and Technical Information of China (English)

    赵健

    2001-01-01

    介绍了一种在数控车床上加工大螺距蜗杆的切削技巧以及相应的数控程序。%The machining skill and relevant NC program of machining worm screw with large pitch using a NC lathe are introduced.

  2. RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules

    Directory of Open Access Journals (Sweden)

    Michaeli Shulamit

    2007-10-01

    Full Text Available Abstract Background In recent years, RNA molecules that are not translated into proteins (ncRNAs have drawn a great deal of attention, as they were shown to be involved in many cellular functions. One of the most important computational problems regarding ncRNA is to predict the secondary structure of a molecule from its sequence. In particular, we attempted to predict the secondary structure for a set of unaligned ncRNA molecules that are taken from the same family, and thus presumably have a similar structure. Results We developed the RNAspa program, which comparatively predicts the secondary structure for a set of ncRNA molecules in linear time in the number of molecules. We observed that in a list of several hundred suboptimal minimal free energy (MFE predictions, as provided by the RNAsubopt program of the Vienna package, it is likely that at least one suggested structure would be similar to the true, correct one. The suboptimal solutions of each molecule are represented as a layer of vertices in a graph. The shortest path in this graph is the basis for structural predictions for the molecule. We also show that RNA secondary structures can be compared very rapidly by a simple string Edit-Distance algorithm with a minimal loss of accuracy. We show that this approach allows us to more deeply explore the suboptimal structure space. Conclusion The algorithm was tested on three datasets which include several ncRNA families taken from the Rfam database. These datasets allowed for comparison of the algorithm with other methods. In these tests, RNAspa performed better than four other programs.

  3. Areva first half 2008 financial results; Areva - Resultats du 1. semestre 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    Operating income: 539 million euros; net income attributable to equity holders of the parent: up 465 million euros to 760 million euros, i.e. 21.45 euros per share; net debt of 2.385 billion euros, i.e. 30.1% of equity (26.2% at 12/31/2007). For 2008 as a whole, the group confirms its outlook for a sharp increase in backlog and in revenue and rising operating income. The backlog rose to 38.123 billion euros at June 30, 2008, up 13.6% compared with the 33.553 billion euros recognized at June 30, 2007. In Nuclear, contributors to growth were the Reactors and Services division (+36%) and the Front End division (+11%). The Transmission and Distribution division posted growth of 41%. First half 2008 revenue rose to 6.168 billion euros, for 14.8% reported growth and 16.0% organic growth. In the nuclear businesses, organic growth was 18.6%, including 31.3% growth in Reactors and Services as new power plant construction projects moved forward and 12.0% growth in Transmission and Distribution business. The group's operating income rose to 539 million euros in the first half of 2008, for a margin rate of 8.7%, compared with 207 million euros in the first half of 2007 and a margin rate of 3.9%. This 332 million euro increase includes: - the strong volume increase in our commercial and industrial operations and the positive impact this had on profitability for all of our divisions; - a substantial operational gain in the Front End division, including a significant dilution gain related to acquisition by Suez of an equity interest in the GB II enrichment plant; - an additional provision on the OL3 contract, made necessary by: cost overruns generated by the use of additional resources needed to meet the schedule and offset the customer's operating practices; and the difficulties and risks on operations managed by some subcontractors. Operating income for the Back End division rose to 400 million euros, an increase of 177 million euros compared with the first half of 2007. The Reactors and Services division had an operating loss of 258 million euros, compared with a loss of 230 million euros in the first half of 2007. The Back End division recorded operating income of 175 million euros up from 95 million euros in the first half of 2007. Operating income for the Transmission and Distribution division was up sharply, by 45%, from 175 million euros in the first half of 2007 to 253 million euros in the first half of 2008. The group's consolidated net income rose to 760 million euros in the first half of 2008, up 465 million euros from the 295 million euros of the first half of 2007. The group's free operating cash flow came to -521 million euros in the first half of 2008. The group's net debt rose to 2.385 billion euros from 1.953 billion euros at the end of 2007. For the full year of 2008, the group confirms its perspectives: A strong increase in revenue and backlog; Increased operating income; Continuation of its capital expenditure program.

  4. f890nc.m77t and f890nc.h77t: MGD77T data and header files for single-beam bathymetry data for field activity F-8-90-NC in Gulf of Farallones, Northern California from 08/05/1990 to 08/17/1990

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with Loran-C RHO-RHO and GPS navigation data was collected as part of the U.S. Geological Survey cruise F-8-90-NC. The cruise was...

  5. f790nc.m77t and f790nc.h77t: MGD77T data and header files for single-beam bathymetry data for field activity F-7-90-NC in the Gulf of Farallones, Northern California from 07/19/1990 to 08/03/1990

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with Loran-C RHO-RHO and GPS navigation data was collected as part of the U.S. Geological Survey cruise F-7-90-NC. The cruise was...

  6. j281nc.m77t and j281nc.h77t: MGD77T data and header files for single-beam bathymetry data for field activity J-2-81-NC in Carmel Bay, Monterey Bay, Northern California from 06/23/1981 to 06/30/1981

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with miniranger navigation data was collected as part of the U.S. Geological Survey cruise J-2-81-NC. The cruise was conducted in...

  7. c179nc.m77t and c179nc.h77t: MGD77T data and header file for single-beam bathymetry data for field activity C-1-79-NC in Northern California from 05/01/1979 to 05/02/1979

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry data along with miniranger navigation data was collected as part of the U.S. Geological Survey cruise C-1-79-NC. The cruise was conducted in...

  8. 硝化棉气凝胶的微结构及热分解特性%Microstructure and Thermal Behavior of NC Aerogel

    Institute of Scientific and Technical Information of China (English)

    于宪峰; 晋苗苗

    2014-01-01

    为研究硝化棉( NC)气凝胶的微结构及其与热性能的关系,用溶胶-凝胶法以及超临界干燥法制备了硝化棉气凝胶。用扫描电子显微镜( SEM)、X射线衍射( XRD)、热重-红外联用( TG-FTIR)表征了其微观结构、结晶性及热性能。结果表明:NC 气凝胶的微观结构为纳米颗粒堆积成的纳米多孔结构。其结晶遭到破坏,呈非晶无序特征。与 NC 相比,NC 气凝胶的 DTG 峰温及 DSC放热峰温度分别提前7℃和11℃,分解热由1429.87 J·g-1提高至1689.21 J·g-1。%To study the microstructure of nitrocellulose( NC)aerogel and its relationship with thermal properties,NC aerogel was prepared by sol-gel method and supercritical drying. The microstructure,crystallizability and thermal properties of the aerogel were characterized by SEM,XRD and TG/DSC-FTIR methods. Results show that:the microstructure of NC aerogel is nano-porous structure accumulated by nano-particles. The crystallization of NC is destroyed in NC aerogel,presenting amorphous disordered state. In comparison with NC,the DTG peak temperature and DSC exothermic peak temperature of NC aerogel shift 7 ℃ and 12 ℃ downwards,respectively,and the decomposition heat increases from 1429.87 J·g-1 to 1689.21 J·g-1.

  9. A Numerical Simulation of the Effect of Buffer Layer Band Gap on the Performances of nc-Si : H Based Solar Cells

    Directory of Open Access Journals (Sweden)

    H. Touati

    2016-06-01

    Full Text Available This paper describes an investigation, by using numerical simulation, into the impacts of i-nc-Si : H buffer layer band gap on the photovoltaic parameters of n-i-p hydrogenated nanocrystalline silicon (nc-Si : H solar cells. The output external cell parameters, like, the short-circuit current (JSC, the open circuit voltage (VOC, the fill factor (FF and efficiency (Eff are simulated by varying the mobility band gap (Eg of i-nc-Si : H buffer layer. Also, the band diagram of nc-Si : H n-i-p solar cell, the electric field and the traped hole density at i/p interface, and the external quantum efficiency, with different values of buffer layer band gap where optimized. The simulation result shows that in valence band and for both interfaces, the band offsets ΔEV1 at p-nc-Si : H (window layer / i-nc-Si : H (buffer layer and ΔEV2 at i-nc-Si : H (buffer layer / i-nc-Si : H (absorber layer can be affected by varying Eg. It is obtained that the values efficiency are 10.89 % and 11.33 % when the value of i-nc-Si : H buffer layer band gap are 1.4 eV and 1.55 eV, respectively. However, the i-nc-Si : H buffer layer band gap of 1.55 eV was optimized for obtaining a better efficiency for n-i-p solar cell based on hydrogenated nanocrystalline silicon.

  10. Transcriptional landscape of ncRNA and Repeat elements in somatic cells

    KAUST Repository

    Ghosheh, Yanal

    2016-12-01

    The advancement of Nucleic acids (DNA and RNA) sequencing technology has enabled many projects targeted towards the identification of genome structure and transcriptome complexity of organisms. The first conclusions of the human and mouse projects have underscored two important, yet unexpected, findings. First, while almost the entire genome is transcribed, only 5% of it encodes for proteins. Thereby, most transcripts are noncoding RNA. This includes both short RNA (<200 nucleotides (nt)) comprising piRNAs; microRNAs (miRNAs); endogenous Short Interfering RNAs (siRNAs) among others, and includes lncRNA (>200nt). Second, a significant portion of the mammalian genome (45%) is composed of Repeat Elements (REs). RE are mostly relics of ancestral viruses that during evolution have invaded the host genome by producing thousands of copies. Their roles within their host genomes have yet to be fully explored considering that they sometimes produce lncRNA, and have been shown to influence expression at the transcriptional and post-transcriptional levels. Moreover, because some REs can still mobilize within host genomes, host genomes have evolved mechanisms, mainly epigenetic, to maintain REs under tight control. Recent reports indicate that REs activity is regulated in somatic cells, particularily in the brain, suggesting a physiological role of RE mobilization during normal development. In this thesis, I focus on the analysis of ncRNAs, specifically REs; piRNAs; lncRNAs in human and mouse post-mitotic somatic cells. The main aspects of this analysis are: Using sRNA-Seq, I show that piRNAs, a class of ncRNAs responsible for the silencing of Transposable elements (TEs) in testes, are present also in adult mouse brain. Furthermore, their regulation shows only a subset of testes piRNAs are expressed in the brain and may be controlled by known neurogenesis factors. To investigate the dynamics of the transcriptome during cellular differentiation, I examined deep RNA-Seq and Cap

  11. Renormalization of local quark-bilinear operators for Nf=3 flavors of SLiNC fermions

    CERN Document Server

    Constantinou, M; Panagopoulos, H; Perlt, H; Rakow, P E L; Schierholz, G; Schiller, A; Zanotti, J M

    2014-01-01

    The renormalization factors of local quark-bilinear operators are computed non-perturbatively for $N_f=3$ flavors of SLiNC fermions, with emphasis on the various procedures for the chiral and continuum extrapolations. The simulations are performed at a lattice spacing $a=0.074$ fm, and for five values of the pion mass in the range of 290-465 MeV, allowing a safe and stable chiral extrapolation. Emphasis is given in the subtraction of the well-known pion pole which affects the renormalization factor of the pseudoscalar current. We also compute the inverse propagator and the Green's functions of the local bilinears to one loop in perturbation theory. We investigate lattice artifacts by computing them perturbatively to second order as well as to all orders in the lattice spacing. The renormalization conditions are defined in the RI$'$-MOM scheme, for both the perturbative and non-perturbative results. The renormalization factors, obtained at different values of the renormalization scale, are translated to the ${...

  12. NC Material Management Module Development%NC系统物料管理模块开发

    Institute of Scientific and Technical Information of China (English)

    梁卫东

    2012-01-01

    介绍如何系统化地进行有线电视的物料管理,并通过对NC供应链系统物料管理模块的开发,利用财务结算的材料费用和仓库管理的材料数量,应用到规划建设的物料管理上,从而实现有线电视工程预算与财务结算数据的对接,更有效地把控工程材料用量,提高了工程物料管理工作的效率。%This paper introduces how to systematically cable material management, and through the NC supply chain system material management module development, the financial settlement of material cost and ware- house management quantity of material, applied to the planning and construction material management. In or- der to achieve CATV project budget and financial settlement data docking, more effectively to control the engi- neering material, for complicated engineering materials management to improve efficiency.

  13. Variable Capacitance Diodes of (p) nc-Si: H/(n) c-Si Heterojunction%(p)nc-Si:H/(n)c-Si异质结变容二极管

    Institute of Scientific and Technical Information of China (English)

    韦文生; 王天民; 张春熹; 李国华; 卢励吾

    2005-01-01

    采用等离子体增强化学气相沉积技术和电子束蒸发技术制备了一种新型的线性缓变异质结变容二极管--Au/Cr合金(电极)/multi-layer(p)nc-Si:H/(n)c-Si/(电极)Au/Ge合金结构.I-V,C-V,G-f以及DLTS的测试结果表明:其电容变化系数远大于单晶硅线性缓变异质结的电容变化系数,正向导电机制符合隧穿辅助辐射-复合模型,这是nc-Si:H层中nc-Si晶粒的量子效应所致;反向电流主要由异质结中空间电荷区的产生电流决定,且反向漏电流小,反向击穿电压高,表现出较好的整流特性.

  14. 基于FANUC数控系统前馈控制提高数控机床控制精度的研究%Research on Machining Precision of NC Machine Based on Feedforward of FANUC NC System

    Institute of Scientific and Technical Information of China (English)

    朱仕学

    2011-01-01

    常规的数控伺服系统的指令滞后问题导致加工指令轨迹同实际轨迹存在形状误差.通过理论计算和实际应用认为:在数控伺服系统中引进前馈控制(即把前馈控制器置于系统的输入端)方法是消除这种不稳定和精度误差最有效的方法.阐述了伺服系统前馈控制技术的设计原理和具体方法.%The routine log of NC servo system' s instruction will cause the form error of the machining instruction to real machining trajectory. The author considers that using feed forward of NC servo system can effectively solve the problem and raise machining precision. The article expounds the design principle and method of how to use NC servo system feed forward.

  15. Study on the catalytic effect of NiO nanoparticles on the thermal decomposition of TEGDN/NC propellant.

    Science.gov (United States)

    Wei, Wenxian; Jiang, Xiaohong; Lu, Lude; Yang, Xujie; Wang, Xin

    2009-09-15

    The catalytic effect of NiO nanoparticles on the thermal decomposition of double-base propellant composed of nitrocellulose (NC) and triethylene glycol dinitrate (TEGDN) has been investigated by thermogravimetry-mass spectrometry (TG-MS) coupling technique. It was shown that adding 2% of NiO nanoparticles to TEGDN/NC propellant can accelerate the thermal decomposition process after around 188 degrees C TG-MS analysis indicated that NiO nanoparticles have resulted in the increase in intensity (peak area) of m/z=27, 28, and 29 MS signals, but the decrease in the intensity of m/z=18, 30, 44 and 46 (peak 2) MS signals during the thermal decompsition. The catalytic mechanism was also discussed in this paper.

  16. 数控车床中的椭圆宏程序%Ellipse Macro Program in NC Lathe

    Institute of Scientific and Technical Information of China (English)

    宣志勇

    2012-01-01

    对于数控专业的初学者学习数控编程,特别是宏程序的编程是比较困难.通过分析数控车床中的椭圆宏程序和论述坐标法,让初学者能够以此作为宏程序学习的一个入门,掌握各种不同曲线宏程序的编辑方法.%For beginners to learn professional NC,NC programming,especially the macro program programming is difficult.Through the analysis of CNC lathe in the ellipse macro program and discussion of the method of coordinate,beginners can learn as an introductory in the macro program,to master various macro program editing method of the curve.

  17. Angelicae Dahuricae Radix Inhibits Dust Mite Extract-Induced Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

    Directory of Open Access Journals (Sweden)

    Hoyoung Lee

    2012-01-01

    Full Text Available We examined whether Angelicae Dahuricae Radix (AR suppresses the development of atopic dermatitis (AD-like skin lesions induced by Dermatophagoides farinae in NC/Nga mice. To investigate the effect of AR, we measured the AD severity score, measured plasma levels of IgE and histamine, and performed histological analysis in NC/Nga mice. We also confirmed the anti-inflammatory effects of AR by measuring TARC/CCL17 production from LPS-treated RAW 264.7 cells and mRNA levels of TARC and MDC/CCL22 in TNF-α/IFN-γ-treated HaCaT cells. 10 mg/day of AR extract was applied for 4 weeks to NC/Nga mice. Both the AR extract and 0.1% tacrolimus suppressed the development of AD-like skin lesions and reduced dermatitis scores of the back and ear skin. AR extracts caused an inhibition of histological changes induced by repeated application of D. farinae and a reduction of IgE and histamine levels in plasma (P<0.05. Furthermore, NO production in LPS-treated RAW 264.7 cells was diminished in a dose-dependent manner, and hTARC production and TARC and MDC mRNA levels in TNF-α/IFN-γ-treated HaCaT cells were diminished by AR. The inhibitory effect of AR on NO, TARC and MDC production may be associated with the suppression of AD-like skin lesions in D. farinae-induced NC/Nga mice.

  18. Superscaling in electron-nucleus scattering and its link to CC and NC QE neutrino-nucleus scattering

    CERN Document Server

    Barbaro, M B; Caballero, J A; Donnelly, T W; Gonzalez-Jimenez, R; Ivanov, M; Udias, J M

    2013-01-01

    The superscaling approach (SuSA) to neutrino-nucleus scattering, based on the assumed universality of the scaling function for electromagnetic and weak interactions, is reviewed. The predictions of the SuSA model for bot CC and NC differential and total cross sections are presented and compared with the MiniBooNE data. The role of scaling violations, in particular the contribution of meson exchange currents in the two-particle two-hole sector, is explored.

  19. A Study on 3D FE Simulation Method of NC Bending Process of Thin-walled Tube

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The numerical control (NC) precision bending process of thin-walled tube is on e of advanced plastic forming processes with high efficiency, forming precision, strength/weight ratio and low cost, thus it is playing more and more important role in manufacturing parts in aerospace and automobile industries. However, the determination of parameters crucial to make sure tube parts qualified is heavil y experience-based and involves repeated trial-and-errors in practice, which makes the production efficiency...

  20. Superscaling in electron-nucleus scattering and its link to CC and NC QE neutrino-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Barbaro, M. B. [Università di Torino and INFN, Sezione di Torino, 10125 Torino (Italy); Amaro, J. E. [Universidad de Granada, 18071 Granada (Spain); Caballero, J. A.; González-Jiménez, R. [Universidad de Sevilla, 41080 Sevilla (Spain); Donnelly, T. W. [CTP, LNS and Department of Physics, MIT, Cambridge, MA 02139 (United States); Ivanov, M. [Institute for Nuclear Research and Nuclear Energy, Sofia 1784 (Bulgaria); Udías, J. M. [Universidad Complutense de Madrid, 28040 Madrid (Spain)

    2015-05-15

    The superscaling approach (SuSA) to neutrino-nucleus scattering, based on the assumed universality of the scaling function for electromagnetic and weak interactions, is reviewed. The predictions of the SuSA model for bot CC and NC differential and total cross sections are presented and compared with the MiniBooNE data. The role of scaling violations, in particular the contribution of meson exchange currents in the two-particle two-hole sector, is explored.

  1. Neospora caninum NC-6 Argentina induces fetopathy in both serologically positive and negative experimentally inoculated pregnant dams.

    Science.gov (United States)

    Bacigalupe, D; Basso, W; Caspe, S G; Moré, G; Lischinsky, L; Gos, M L; Leunda, M; Campero, L; Moore, D P; Schares, G; Campero, C M; Venturini, M C

    2013-07-01

    Neospora caninum infection is a major cause of abortion in cattle. The objectives of this study were to genetically characterize the N. caninum NC-6 Argentina isolate using a multilocus microsatellite analysis approach and to study its biological behavior by experimental inoculations into seronegative and seropositive pregnant cattle, evaluating the humoral and cellular immune response elicited and the occurrence of transplacental transmission and fetopathy. Pregnant cows (65 days of gestation) seropositive and seronegative to N. caninum were intravenously inoculated with tachyzoites of the NC-6 Argentina N. caninum strain and slaughtered at 108 ± 2 days of gestation. Serum samples were analyzed for N. caninum antibodies by indirect fluorescent antibody test. The cellular immune response was analyzed by detection of gamma interferon (γIFN) production in blood cells. Tissue samples from dams, fetuses, and placental cotyledons were processed by histopathological and immunohistochemical techniques and examined for N. caninum DNA by PCR. Positive DNA samples were further analyzed by multilocus microsatellite typing for N. caninum. Inoculated animals had significantly higher N. caninum antibody titers and γIFN production than control animals. One seropositive inoculated cow aborted, one seronegative cow had a non-viable fetus, and the remaining fetuses from the experimentally inoculated dams had histopathologic lesions. The PCR was positive in 3/4 fetuses from seronegative inoculated cows and in 2/3 fetuses from seropositive inoculated cows. Multilocus microsatellite analysis revealed that the N. caninum DNA present in fetuses and placentas had an identical pattern to NC-6 Argentina strain. The NC-6 Argentina strain proved to be able to cross the placenta and to induce fetopathy in both the seropositive and seronegative dams.

  2. Development of maskless electron-beam lithography using nc-Si electron-emitter array

    Science.gov (United States)

    Kojima, A.; Ikegami, N.; Yoshida, T.; Miyaguchi, H.; Muroyama, M.; Nishino, H.; Yoshida, S.; Sugata, M.; Cakir, S.; Ohyi, H.; Koshida, N.; Esashi, M.

    2013-03-01

    This study demonstrated our prototyped Micro Electro Mechanical System (MEMS) electron emitter which is a nc-Si (nanocrystalline silicon) ballistic electron emitter array integrated with an active-matrix driving LSI for high-speed Massively Parallel Electron Beam Direct Writing (MPEBDW) system. The MPEBDW system consists of the multi-column, and each column provides multi-beam. Each column consists of emitter array, a MEMS condenser lens array, an MEMS anode array, a stigmator, three-stage deflectors to align and to scan the multi beams, and a reduction lens as an objective lens. The emitter array generates 100x100 electron beams with binary patterns. The pattern exposed on a target is stored in one of the duplicate memories in the active matrix LSI. After the emission, each electron beam is condensed into narrow beam in parallel to the axis of electron optics of the system with the condenser lens array. The electrons of the beams are accelerated and pass through the anode array. The stigmator and deflectors make fine adjustments to the position of the beams. The reduction lens in the final stage focuses all parallel beams on the surface of the target wafer. The lens reduces the electron image to 1%-10% in size. Electron source in this system is nc-Si ballistic surface electron emitter. The characteristics of the emitter of 1:1 projection of e-beam have been demonstrated in our previous work. We developed a Crestec Surface Electron emission Lithography (CSEL) for mass production of semiconductor devices. CSEL system is 1:1 electron projection lithography using surface electron emitter. In first report, we confirmed that a test bench of CSEL resolved below 30 nm pattern over 0.2 um square area. Practical resolution of the system is limited by the chromatic aberration. We also demonstrated the CSEL system exposed deep sub-micron pattern over full-field for practical use. As an interim report of our development of MPEBDW system, we evaluated characteristics of the

  3. Fabrication Technology and Characteristics of a Magnetic Sensitive Transistor with nc-Si:H/c-Si Heterojunction.

    Science.gov (United States)

    Zhao, Xiaofeng; Li, Baozeng; Wen, Dianzhong

    2017-01-22

    This paper presents a magnetically sensitive transistor using a nc-Si:H/c-Si heterojunction as an emitter junction. By adopting micro electro-mechanical systems (MEMS) technology and chemical vapor deposition (CVD) method, the nc-Si:H/c-Si heterojunction silicon magnetically sensitive transistor (HSMST) chips were designed and fabricated on a p-type orientation double-side polished silicon wafer with high resistivity. In addition, a collector load resistor ( R L ) was integrated on the chip, and the resistor converted the collector current ( I C ) to a collector output voltage ( V out ). When I B = 8.0 mA, V DD = 10.0 V, and R L = 4.1 kΩ, the magnetic sensitivity ( S V ) at room temperature and temperature coefficient ( α C ) of the collector current for HSMST were 181 mV/T and -0.11%/°C, respectively. The experimental results show that the magnetic sensitivity and temperature characteristics of the proposed transistor can be obviously improved by the use of a nc-Si:H/c-Si heterojunction as an emitter junction.

  4. Baryons and Low-Density Baryonic Matter in 1+1 Dimensional Large N_c QCD with Heavy Quarks

    CERN Document Server

    Adhikari, Prabal; Jamgochian, Arec; Kumar, Nilay

    2012-01-01

    This paper studies baryons and baryonic matter in the combined large N_c and heavy quark mass limits of QCD in 1+1 dimension. In this non-relativistic limit, baryons are composed of N_c quarks that interact, at leading order in N_c, through a color Coulomb potential. Using variational techniques, very accurate calculations of single baryon masses and interaction energies of low-density baryon crystal are performed. These results are used to cross-check a general numerical approach applicable for arbitrary quark masses and baryon densities recently proposed by Bringoltz, which is based on a lattice in a finite box with periodic boundary conditions. The Bringoltz method differs from a previous approach of Salcedo, et al. in its treatment of a finite box effect - namely gauge configurations that wind around the box. One might expect these effects to be small for large enough boxes, in which the baryon density approaches zero to high accuracy at the edges. However, the effects of these windings appear to be quite...

  5. Enhancing Parent Involvement in NC-CCSS for K-2 Mathematics

    Science.gov (United States)

    Johnson, D.

    2014-12-01

    Key Terms:Parent Involvement, Common Core State Standards, Homework, K - 2 Mathematics In this study, the 2014 REU math team developed and provided a workshop that assisted parents in understanding the North Carolina Common Core State Standards for K-2 Mathematics to assist with student homework assignments. Parent involvement is defined as parent participating in the educational processes and experiences of their children. A chi-square analysis was used to analyze data collected from the pre survey and the post survey administered to participants in the workshop. The study revealed all of the individual components of parent involvement were positively and significantly related to educational goals. The study identified various aspects of parent involvement that yielded statistically significant results in affirming that parent involvement attributed to urban student achievement. These findings were particularly helpful for indicating which kinds of parent involvement influenced academic success. Most notably, parent expectations and styles demonstrated a strong relationship with scholastic outcomes. Parent expectations and styles created an educationally oriented ambience that established an understanding of the certain level of support the child needed to succeed academically. The REU mathematics team focused on three essential questions in this study: (1) What practices will increase parent awareness of K-2 NC-CCSS for mathematics at P. W. Moore Elementary School? (2) What methods can be used to strengthen parent skills in assisting with mathematics homework assignments at P. W. Moore Elementary School? (3) What actions can be taken to motivate parent involvement in the school improvement process focusing on mathematics at P. W. Moore Elementary School?

  6. A benthic carbon budget for the continental slope off Cape Hatteras, N.C.

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, C.J.; Blair, N.E.; DeMaster, D.J.; Jahnke, R.A.; Martens, C.S.

    1999-01-31

    The continental slope off Cape Hatteras, N.C. from approximately 36{degree} 00 minutes N to 35{degree} 20 minutes N is a region of relatively rapid sediment accumulation, organic matter deposition and subsequent remineralization. The measured fluxes are the highest reported for the slope off the eastern US Sediment accumulation rates range from 40 to 140 cm ky{sup -1}. Organic carbon deposition rates range from 3.5 to 7.4 moles C m{sup -2} yr{sup -1}. The areal coverage of this ''depocenter'' is probably controlled by interactions between physical oceanographic processes and the rugged topography of the seafloor. The organic matter deposited on the seafloor is primarily marine in origin and a mix of old and fresh particles. 73-93% of the depositing detritus is rapidly oxidized near the sediment/water interface. The controls on subsurface remineralization appear to be a complex function of the relative amount of metabolizable carbon delivered to the seabed both now and in the distant past (>=500ybp) and the extent of seabed irrigation. The age of DIC and CH{sub 4} produced within the seabed indicates that relatively young, reactive carbon is advected below the sediment surface and fuels subsurface remineralization. The stable isotopic composition of DIC produced within the seabed indicates the selective degradation of {sup 13}C-enriched fractions of the organic matter. The metabolizable fraction has a carbon isotopic signature of approx. -18{per_thousand};, while the organic matter that survives degradation and is buried has a d{sup 13}C closer to -20{per_thousand}.

  7. Clinical significance of anti-ds-DNA-NcX-ELISA detection in the diagnosis of systemic lupus erythematosus%NcX-ELISA法检测抗ds-DNA在系统性红斑狼疮中的诊断价值

    Institute of Scientific and Technical Information of China (English)

    戴伟良; 蔡早育; 郑雪莲

    2011-01-01

    目的 探讨双链DNA抗体(抗ds-DNA)的检测方法,寻找1种高特异性、高敏感性的检测方法,为临床诊断及治疗系统性红斑狼疮(SLE)提供可靠的实验依据.方法 分别采用间接荧光免疫法(IIFA)、普通ELISA 法、放射免疫法(RIA)及NcX-ELISA法,测定50例SLE患者、60例非SLE风湿病患者及30例健康对照者血清中抗ds-DNA.结果 采用IIFA法、普通ELISA 法、RIA法及NcX-ELISA法测定抗ds-DNA,诊断特异性分别为96.7%、93.3%、95.0%、98.3%,其中以NcX-ELISA法特异性最高,普通ELISA法最低;诊断率分别为71.8%、73.6%、76.4%、86.4%,其中以NcX- ELISA法诊断效率最高,IIFA 法最低;检测的敏感性分别为42.0%、50.0%、54.0%、72.0%,以NcX- ELISA法检测敏感性最高,与RIA法相比差异无统计学意义(P>0.05),与普通ELISA法比较差异有统计学意义(P<0.05),与IIFA法比较差异有统计学意义(P<0.005).结论 普通ELISA 法特异性低,IIFA法敏感性低,RIA法虽然敏感性、特异性较高,但是容易污染环境;NcX-ELISA法具有高特异性、高敏感性、高诊断率及可批量检测的优点,是检测抗ds-DNA的理想方法.%Objective To investigate suitable method with high sensitivity and specificity for the detection of anti double stranded DNA(anti ds DNA) antibody and provide credible basis for diagnosing and monitoring systemic lupus erythematosus (SLE).Methods Serum anti ds DNA antibody in patients with SLE (n 50) ,patients with other autoimmune diseases(n 60) and healthy controls (n = 30) were measured by indirect immunofluorescent assay (IIFA), common enzyme linked immunosorbent assay (ELISA) ,radioimmunoassay(RIA) and anti ds DNA NcX ELISA respectively. Results The diagnostic specificity of IIFA,common ELISA,RIA and anti ds DNA NcX ELISA in the detection of serum anti ds DNA antibody was 96. 7%, 93. 3%, 95. 0% and 98.3 % respectively. The diagnostic efficiency of them was 71.8 %, 73.6 %, 76.4 % and 86.4

  8. Effects of Nitrogen Rates on Growth and Yield of Tobacco NC102%施氮量对NC102品种生长发育及产质量的影响

    Institute of Scientific and Technical Information of China (English)

    谭炳昱; 吕平; 刘莉; 杨永花; 刘勇; 朱先志; 王滨; 徐蕊; 王梅勋; 牛纪军

    2015-01-01

    为探讨NC102品种的良种良法配套技术,满足工业卷烟配方需求,采用田间试验的方法,研究了施氮量对NC102品种生长发育及产质量的影响。结果表明,施氮量对NC102品种的株高、叶面积、产量等有显著影响。在中等肥力(碱解氮50~80 mg/kg)条件下,施氮量为75、90 kg/hm2处理明显好于60、105 kg/hm2处理,其大田整齐度高,田间病害发生较轻,产值效益较高。其中,施氮量为75 kg/hm2的均价及产值效益最高。从烤后烟叶化学成分来看,施氮量为90、75 kg/hm2时,糖碱比更协调,更容易被目前卷烟工业所接受。综合分析,施氮量为75 kg/hm2,NC102品种的烟叶产质量最好。%In order to explore the supporting technologies on fine seed and fine method of NC102 suitable for local natural conditions, and meet the need of industrial cigarette formula, effects of nitrogen rate on plants growth and yield of NC102 were studied by field experiment. The experiment set three replicates and four different nitrogen rate levels (60, 75, 90, 105 kg/ha). The results showed that nitrogen rate had significant effect on plant height, leaf area and yield. According to comprehensive analysis, higher field uniformity, lighter incidence of field diseases and higher production efficiency were recorded in the treatment of 75 and 90 kg/ha nitrogen rate, compared with the treatments of 60 and 105 kg/ha under moderate fertility (alkaline hydrolysis nitrogen 50-80 mg/kg). The highest average price and production efficiency were observed in the treatment of 75 kg/ha nitrogen rate. Based on chemical composition of flue cured tobacco leaves, when nitrogen rates were 75 and 90 kg/ha, sugar alkali ratios of the leaves were more harmonious, and they were accepted more easily by the cigarette industry. On the consideration of comprehensive analysis, the treatment of 75 kg/ha nitrogen rate was best on growth and yield of tobacco NC102.

  9. 牛源犬新孢子虫NcSAG1基因重组腺病毒株的构建及动物免疫试验%Construction and Animal Experiment of a Recombinant Adenovirus Expressing NcSAG1 Protein of Bovine Neospora caninum

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发

    2012-01-01

    [目的]构建表达牛源犬新孢子虫NcSAG1基因的重组腺病毒株,并接种Ba1b/c小鼠,评价重组腺病毒株对Ba1b/c小鼠的体液免疫和细胞免疫应答水平.[方法]PCR扩增牛源犬新孢子虫NcSAG1基因,构建pMD18-T-NcSAG1克隆质粒和pCR259-NcSAG1重组腺病毒穿梭质粒;将鉴定正确的pCR259-NcSAG1重组腺病毒穿梭质粒依次转化HighQ-1 Transpose-Ad 294和HighQ-1 感受态细胞,构建Transpose-Ad-NcSAG1重组腺病毒表达质粒;PacI酶切线性化后,脂质体介导转染QBI-HEK 293细胞包装重组腺病毒Ad5-NcSAG1,应用PCR和Western blotting技术检测Ad5-NcSAG1及其表达蛋白产物.测定Ad5-NcSAG1重组腺病毒滴度后,接种Balb/c小鼠,测定小鼠血清中IgG特异性抗体和细胞因子IFN-γ、IL-4水平,以此评价重组腺病毒株的免疫应答效果.[结果]扩增的牛源犬新孢子虫NcSAG1基因大小为982bp,与GenBank中发表的NcSAG1(AF132217)核苷酸序列的同源性为99.2%;经PCR和Western blotting检测,重组腺病毒Ad5-NcSAG1在QBI-HEK 293细胞中包装成功,表达蛋白的分子量为33kD,具有较好的反应原性;测得重组腺病毒Ad5-NcSAG1滴度为1010TCID50/mL,Ad5-NcSAG1接种Ba1b/c小鼠后,能够诱导产生高水平的IgG特异性抗体和IFN-γ、IL-4细胞因子.说明Ad5-NcSAG1重组腺病毒对Ba1b/c小鼠产生了较强的体液免疫和细胞免疫应答.[结论]成功构建了牛源犬新孢子虫NcSAG1基因的重组腺病毒株,该毒株能够诱导Ba1b/c小鼠产生高水平的体液免疫和细胞免疫应答,为犬新孢子虫新型疫苗的临床试验奠定了基础.%[Objective] A recombinant adenovirus expressing NcSAG1 protein of bovine N. caninum was constructed. Balb/c mice were immunized with the recombinant adenovirus to evaluate the levels of humoral and cellular immune responses. [Method] NcSAGI gene of bovine N. caninum was amplified by PCR. pMD18-T-NcSAGl and pCR259- NcSAGI were constructed. The correct pCR259-NcSAGl was transformed

  10. Integrated Analysis of Dysregulated ncRNA and mRNA Expression Profiles in Humans Exposed to Carbon Nanotubes.

    Directory of Open Access Journals (Sweden)

    Anna A Shvedova

    Full Text Available As the application of carbon nanotubes (CNT in consumer products continues to rise, studies have expanded to determine the associated risks of exposure on human and environmental health. In particular, several lines of evidence indicate that exposure to multi-walled carbon nanotubes (MWCNT could pose a carcinogenic risk similar to asbestos fibers. However, to date the potential markers of MWCNT exposure are not yet explored in humans.In the present study, global mRNA and ncRNA expression profiles in the blood of exposed workers, having direct contact with MWCNT aerosol for at least 6 months (n = 8, were compared with expression profiles of non-exposed (n = 7 workers (e.g., professional and/or technical staff from the same manufacturing facility.Significant changes in the ncRNA and mRNA expression profiles were observed between exposed and non-exposed worker groups. An integrative analysis of ncRNA-mRNA correlations was performed to identify target genes, functional relationships, and regulatory networks in MWCNT-exposed workers. The coordinated changes in ncRNA and mRNA expression profiles revealed a set of miRNAs and their target genes with roles in cell cycle regulation/progression/control, apoptosis and proliferation. Further, the identified pathways and signaling networks also revealed MWCNT potential to trigger pulmonary and cardiovascular effects as well as carcinogenic outcomes in humans, similar to those previously described in rodents exposed to MWCNTs.This study is the first to investigate aberrant changes in mRNA and ncRNA expression profiles in the blood of humans exposed to MWCNT. The significant changes in several miRNAs and mRNAs expression as well as their regulatory networks are important for getting molecular insights into the MWCNT-induced toxicity and pathogenesis in humans. Further large-scale prospective studies are necessary to validate the potential applicability of such changes in mRNAs and miRNAs as prognostic markers

  11. 提高数控加工质量的工艺措施%Improve the Quality of NC Machining Process Measures

    Institute of Scientific and Technical Information of China (English)

    窦金平

    2012-01-01

    在数控加工中,除了受机床、刀具、夹具的制造误差和安装误差的影响外,加工质量还与数控加工中所采取的工艺措施密切相关.从加工工艺角度出发,论述了提高数控加工精度和零件表面加工质量的若干措施,以利于高效地使用数控机床.%In NC machining, in addition to effected by manufacture errors and installation errors of machine tool, tool, fixture, machining quality is closely related to process measures taken in NC machining. From the process point of view, a number of measures for improving NC machining accuracy and surface quality of parts were discussed so as to use NC machine tools efficiently.

  12. 500-Year Floodplains, NC Floodplain Mapping Program data, Published in 2007, 1:12000 (1in=1000ft) scale, Iredell County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 500-Year Floodplains dataset, published at 1:12000 (1in=1000ft) scale, was produced all or in part from LIDAR information as of 2007. It is described as 'NC...

  13. Index Grids, NC Stateplane 5000' Index Grid, Published in 2009, 1:2400 (1in=200ft) scale, Iredell County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Index Grids dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Other information as of 2009. It is described as 'NC Stateplane...

  14. 100-Year Floodplains, NC Floodplain Mapping Program data, Published in 2007, 1:12000 (1in=1000ft) scale, Iredell County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This 100-Year Floodplains dataset, published at 1:12000 (1in=1000ft) scale, was produced all or in part from LIDAR information as of 2007. It is described as 'NC...

  15. Work on probability distribution of breakdown of NC press%数控压力机故障概率分布研究

    Institute of Scientific and Technical Information of China (English)

    张强; 马立强; 贾亚洲

    2001-01-01

    开发了分析数控机床可靠性的专用软件。建立了数控压力机的操作和维修数据库。故障数据验证了数控压力机故障分布符合指数分布,并给出了数控压力机可靠性特性的计算方法。%Special software of reliability analysis of NC machine-tool has been developed with establishment of operation and maintenance database of NC press. The distribution of breakdown of NC press has been proved to accord with exponent distribution. Calculating method of reliability characteristics of NC press has been offered.

  16. 我国数控产业发展政策研究%Study on the Policies of National NC Development

    Institute of Scientific and Technical Information of China (English)

    杨皖苏; 严鸿和

    2001-01-01

    针对我国数控产业发展所面临的规模小、产业集中度低、资金投入不足、技术改造乏力、技术创新能力不强,数控机床配套件生产落后、数控专业人才缺乏等主要问题,提出国家在扶持数控产业发展方面应采取的具体政策。%In the view of NC industry development in China, there are many problems such as small scale, low centralization, slow industrialization, lack of bankroll support, single investment channel, weak technical innovation and reconstruction, under-developed NC functional components, lack of NC professional etc. The paper points out that the state should take concrete policies in supporting the development of NC industry.

  17. Inhibition of Triton X-100/n-C5H11OH/H2O System on Hydrolysis of Cephanone

    Institute of Scientific and Technical Information of China (English)

    QIAN Jun-hong; GUO Rong; ZHU Jun

    2004-01-01

    The hydrolysis of cephanone in Triton X-100 micelle and Triton X-100/n-C5H11OH/H2O(O/W) microemulsion were studied by means of UV-Vis absorption spectroscopy. The results show that compared with water, Triton X-100 micelle and Triton X-100/n-C5H11OH/H2O(O/W) microemulsion can inhibit the hydrolysis of cephanone. The inhibition effects of Triton X-100 micelle and Triton X-100/n-C5H11OH/H2O(O/W) microemulsion on the hydrolysis of cephanone are related to the location of cephanone in the interphases of Triton X-100 micelles and Triton X-100/n-C5H11OH/H2O(O/W) microemulsion droplets.

  18. PROGRAM TECHNOLOGY OF NC TURNING DRUM-TYPE SHAFTS%腰鼓形轴类零件数控车削加工的编程技术

    Institute of Scientific and Technical Information of China (English)

    樊琳

    2001-01-01

    介绍数控车床加工腰鼓形轴类零件的编程技术,阐述其编程原理及数据处理方法。%This paper presents the programming technique on machining drum-type shaft in NC lathe.The methods of data processing and the principles of NC machining are discussed in detail.

  19. 提高数控效率,加快新支线飞机研制%Raising NC Efficiency, Speeding Development of New Regional Airliner

    Institute of Scientific and Technical Information of China (English)

    易志斌

    2001-01-01

    The status quo of the domestic NC technology and the gap between domestic and international levels are analyzed. The aim and tactics for developing the NC technology in China are presented.%分析了国内数控技术的现状及其与国际水平的差距,提出了发展我国数控技术的目标和策略。

  20. Étude du comportement structural de l'alliage NC 19 Fe Nb (Inconel 718)

    Science.gov (United States)

    Slama, C.; Cizeron, G.

    1997-03-01

    In the as-received state (following a double treatment at 720 and 620 °C), the structure of INC 718 consists of a γ matrix, intergranular β precipitates and (Nb,Ti)C carbides; moreover, γ{'} and γ{''} phases have precipitated in the matrix. Using different methods, the structural behaviour was analyzed which led to distinguish the temperature ranges in which occurs precipitation or dissolution of β, γ{'} and γ{''} phases on heating and to define the optimum conditions of homogeneization. Furthermore a CCT diagram for INC 718 has been drawn showing the respective precipitation of γ{'}, γ{''} and β phases as a function of the cooling rate applied from 990 °C. L'étude de l'alliage Inconel 718 (NC 19 Fe Nb) a permis de montrer que sa structure, dans l'état de livraison (après double revenu à 720 puis 620 °C), consiste en une matrice γ avec des précipités β intergranulaires et des carbures du type (Nb,Ti) C ; en outre, la matrice contient des précipités des phases γ{''} et γ{'}. L'analyse du comportement structural de l'alliage à l'aide de différentes méthodes physiques a conduit à délimiter les domaines de température dans lesquels interviennent, au chauffage, la précipitation ou la dissolution des phases β, γ{'}, γ{''} et de définir les conditions optimales d'homogénéisation. Le diagramme T.R.C. de l'Inconel 718 a ensuite été tracé : les intervalles de température dans lesquels interviennent les précipitations respectives des phases γ{'}, γ{''} et β en fonction de la vitesse de refroidissement imposée depuis 990 °C, ont ainsi pu être précisés.

  1. Optimal Parameters Design of NC-OFDM Systems with the Consideration of HPA Nonlinearity%考虑HPA非线性的NC-OFDM系统最优参数设计

    Institute of Scientific and Technical Information of China (English)

    朱春华; 韩力; 杨守义

    2011-01-01

    给出了计算非连续OFDM(NC-OFDM)系统带外功率泄漏和主用户(PU)频带干扰功率的数学模型,在此基础上,把NC-OFDM系统参数设计问题转化为次用户(SU)频谱开销和主用户(PU)干扰温度限制下的非线性规划问题的优化求解.给出了NC-OFDM系统最优参数与高功率放大器(HPA)的输入回退(IBO)参数、PU频带占用率和PU干扰温度容限之间的关系.仿真结果表明,当PU频带占用率和干扰容限给定的条件下,求解所建立的优化问题可以为SU设计最佳的系统参数:最少的保护载波数及系统对功率放大器IBO参数的要求.%A mathematical model for computing the out-of-band (OOB) leakage radiation in NC OFDM systems and the interference to the adjacent primary users (Pus) is presented in this paper. Based on this mathematical model, the optimal parameters could be obtained by solving the nonlinear programming (NLP) problem subject to secondary users(Sus)' spectrum overhead and Pus' occupancy rate r. The results showed the close relationship between the number of guard subcarriers and the parameters of input back off (IBO) as well as PU occupancy r and interference temperature tolerance. The simulation results have shown that, under the conditions of given PU occupancy r and PU interference temperature limit, the solution of proposed programming problem can be used to design the optimal system parameters for secondary users with the smallest number of guard subcarriers and the demand of system to the parameters of IBO.

  2. 表达牛源犬新孢子虫NcSRS2基因重组腺病毒的构建及免疫原性分析%Construction of a Recombinant Adenovirus Expressing NcSRS2 Protein of Bovine Neospora Caninum and Immunogenicity Analysis of the Protein

    Institute of Scientific and Technical Information of China (English)

    贾立军; 于龙政; 张守发

    2012-01-01

    为构建牛源犬新孢子虫NcSRS2基因重组腺病毒,并分析其免疫原性,PCR扩增牛源犬新孢子虫NcSRS2基因,构建克隆质粒pMD18-T-NcSRS2、重组腺病毒穿梭质粒pCR259-NcSRS2及表达质粒Transpose-AdNcSRS2,脂质体介导转染QBI-HEK293细胞,包装重组腺病毒Ad5-NcSRS2,PCR检测重组腺病毒NcSRS2基因,IFAT和Western blotting检测NcSRS2基因在QBI-HEK293细胞中的表达,测定病毒滴度后,收集病毒液免疫BALB/c小鼠,间接ELISA检测小鼠血清IgG抗体水平.结果显示,扩增的牛源犬新孢子虫NcSRS2基因大小为1 227 bp,与GenBank中发表的NcSRS2( AF061249)核苷酸序列相似性为99%;重组腺病毒Ad5-NcSRS2在293细胞中包装成功,表达蛋白的相对分子质量为43 ku,具有较好的反应原性;测得重组腺病毒Ad5-NcSRS2滴度为109TCID50·mL-1,间接ELISA检测二免后3周BALB/c小鼠血清中IgG抗体效价达1 ∶ 2 048.本研究成功构建了具有良好免疫原性的重组腺病毒Ad5-NcSRS2,为牛源犬新孢子虫NcSRS2基因重组腺病毒载体疫苗的研制奠定了基础.%In order to construct a recombinant adenovirus expressing NcSRS2 protein of bovine Neospora Caninum, NcSRS2 gene of bovine Neospora Caninum was amplified by PCR, pMD18-T-NcSRS2, pCR259-NcSRS2 and Transpose-Ad-NcSRS2 were constructed in this research. Coated with liposome, Transpose-Ad-NcSRS2 was transfected into QBI-HEK293 cells to package recombinant adenovirus Ad5-NcSRS2. Recombinant adenovirus NcSRS2 gene was detected by PCR. The expression of NcSRS2 gene in QBI-HEK293 cells was detected by IFAT and Western blotting. After the virus titer was determined, the virus fluid was collected to inoculate BALB/c mice and IgG antibody levels in the sera were measured by indirect ELISA. The size of NcSRS2 gene was 1 227 bp. The nucleotide sequence of the gene shared 99% homology with that in GenBank (AF061249). Recombinant adenovirus Ad5-NcSRS2 was successfully packaged in 293 cells. The protein

  3. Optimization of flask culture medium and conditions for hyaluronic acid production by a streptococcus equisimilis mutant nc2168

    Directory of Open Access Journals (Sweden)

    Yong-Hao Chen

    2012-12-01

    Full Text Available A mutant designated NC2168, which was selected from wild-type Streptococcus equisimilis CVCC55116by ultraviolet ray combined with60Co-γ ray treatment and does not produce streptolysin, was employed to produce hyaluronic acid (HA. In order to increase the output of HA in a flask, the culture medium and conditions for NC2168 were optimized in this study. The influence of culture medium ingredients including carbon sources, nitrogen sources and metal ions on HA production was evaluated using factional factorial design. The mathematical model, which represented the effect of each medium component and their interaction on the yield of HA, was established by the quadratic rotary combination design and response surface method. The model estimated that, a maximal yield of HA could be obtained when the concentrations of yeast extract, peptone, glucose, and MgSO4 were set at 3 g/100 mL, 2 g/100 mL, 0.5 g/100 mL and 0.15 g/100 mL, respectively. Compared with the values obtained by other runs in the experimental design, the optimized medium resulted in a remarkable increase in the output of HA and the maximum of the predicted HA production was 174.76 mg/L. The model developed was accurate and reliable for predicting the production of HA by NC2168.Cultivation conditions were optimized by an orthogonal experimental design and the optimal conditions were as follows: temperature 33ºC, pH 7.8, agitation speed 200 rpm, medium volume 20 mL.

  4. 犬新孢子虫NcAMA1基因重组腺病毒穿梭质粒的构建及其真核表达%Construction and eukaryotic expression of the recombinant adenovirus shuttle plasmid with NcAMA1 gene of Neospora caninum

    Institute of Scientific and Technical Information of China (English)

    郭焕平; 贾立军; 于龙政; 薛书江; 高洋; 李男礼; 张守发

    2014-01-01

    为构建犬新孢子虫NcAMA1基因重组腺病毒穿梭质粒,并在真核细胞中表达,以重组质粒pVAX1-NcAMA1为模板,PCR扩增了NcAMA1基因,以此构建了pMD18T-NcAMA1重组克隆质粒;对该重组克隆质粒进行双酶切鉴定后,将其亚克隆至腺病毒穿梭载体pCR259中.应用脂质体介导转染法将经PCR鉴定和酶切鉴定正确的pCR259-NcAMA1重组穿梭质粒转染293细胞,应用IFAT和Western-blot技术检测了AMA1基因在293细胞中的表达情况.结果显示,扩增的NcAMA1基因长度为1 695 bp,构建的重组腺病毒穿梭质粒pCR259-NcAMA1能在293细胞中获得瞬时表达,表达蛋白的分子质量约为68 ku.

  5. 高档数控装备的发展趋势%Development Trends of High-end NC Equipment

    Institute of Scientific and Technical Information of China (English)

    王太勇; 乔志峰; 韩志国; 董靖川; 支劲章

    2011-01-01

    综合介绍了现今高档数控装备各关键技术的发展趋势,首先,结合机床关键功能部件的发展状况,讲述了数控机床在高速、高精度、高效率、高可靠性方面的主流发展动态,并进一步指出机床的可靠性是影响我国机床企业市场竞争能力的关键因素;然后,结合当前高档数控系统在智能化、开放式、网络化等方面的发展,阐述了最新的数字化控制技术对高档数控技术的重要影响及其未来发展方向,并介绍了国内外最新的相关研究成果;最后,结合国内数控技术的发展现状,提出了关于高档数控装备发展的相关建议.%This paper introduced the key technology's development trend of a modern high grade NC equipment.Firstly, according with the development of the key functional units in a machine tool,the paper discussed the mainstream development of the NC machine tool in the aspect of high speed,high precision,high efficiency and high reliability, and further pointed out the reliability of machine tool was the key factor that affected the market competitiveness of China machine tool companies.Secondly, with the continuous development of high—grade NC system in intelligence, open, networking and other aspects, the future development direction and important impact on the CNC technology of the latest digital control technology were described and the latest research results both at home and abroad were also introduced.Finally, combining with the current development situation of domestic NC industry, the relevant individual recommendations about the development of high—grade digital equipment were proposed.

  6. Current development of the ENTSO-E NC RfG in the light of European wind integration

    Energy Technology Data Exchange (ETDEWEB)

    Duddy, Joe [RES Ltd., Belfast (United Kingdom); Martin, Frank; Skrypalle, Inga [Siemens Wind Power A/S, Brande (Denmark); Hulle, Frans van [EWEA, Brussels (Belgium); Wachtel, Stephan [GE Energy, Hamburg (Germany)

    2012-07-01

    Over the entire development of the NC RfG EWEA has been in dialogue with ENTSO-E. EWEA is concerned that network operators tend to increase the compulsory minimum technical connection requirements for wind power plants without clearly explaining the needs (system planning and analyses results, cost-benefit-analyses, etc.) in a transparent way. Grid codes in Europe should at first consider ancillary services market options instead of compulsory requirements to be fulfilled without specific remuneration. The compulsory technical requirements for all generators must therefore focus on the essential aspects of technical performances, leaving an opening for ancillary services within adequately implemented markets. (orig.)

  7. Influence of Neutron Shell Closure (Nc=126) on Prescission Particle Emission of Fissioning Systems 216,224Th

    Institute of Scientific and Technical Information of China (English)

    叶巍

    2003-01-01

    The effect of neutron shell closure Nc = 126 on the prescission-particle emission of 216Th and 224Th nuclei is investigated within the framework of an extensive Smoluchowski equation. It is found that there is a large difference in the prescission neutron multiplicity for the two Th nuclei, indicating a strong shell effect in neutron emission. Moreover, shell effects on particle emission are also investigated as functions of excitation energy,angular momentum and nuclear viscosity. The results show that with increasing excitation energy shell effects in prefission neutron evolve from continual strength to gradual weakness. Both high angular momenta and low viscosity weaken the shell effects on the particle emission.

  8. Construction of a eukaryotic expression vector and its expression of NcSAG1-NcSRS2 fusion gene of Neospora caninum%新孢子虫SAG1-SRS2融合基因真核表达质粒的构建及表达

    Institute of Scientific and Technical Information of China (English)

    卢计委; 刘群; 汪明

    2007-01-01

    根据犬新孢子虫NcSAG1-NcSRS2融合基因序列,设计了1对含有Kozak序列、终止密码子、BamH Ⅰ和XhoⅠ酶切位点的引物,以含有NcSAG1-NcSRS2融合基因的质粒pGEX-tNcP43-P36为模板,经PCR 扩增获得NcSAG1-NcSRS2融合基因片段,用BamH Ⅰ和XhoⅠ双酶切该片段,回收得到含有以上2 个酶切位点黏端的NcSAG1-NcSRS2融合基因,将此基因片段克隆至相同酶切回收后的pcDNA3.1 (+) 真核表达载体中,获得重组质粒pcNCSAG1-SRS2.经PCR 鉴定、限制性内切酶酶切分析和克隆片段序列测定、比较,证实了重组质粒的正确性.将构建好的真核表达质粒转染到COS-7细胞中进行瞬时表达,经免疫荧光检测,证实了该载体能在细胞内进行蛋白表达.

  9. Investigation on the Compatibility of NC/PEG Blended System%NC/PEG共混体系的相容性研究

    Institute of Scientific and Technical Information of China (English)

    康冰; 王利刚; 李笑江; 宋振伟; 丁黎

    2014-01-01

    The compatibility of nitrocellulose/polyethylene glycol (NC/PEG)blended system with different mass ratio was studied by DSC and DMA.Results show that with increasing the content of NC in NC/PEG blended system,the melting point,crystallinity and entropy of crystallization of PEG decrease obviously.The value of interaction parameterχ1,2 of the blended component is negative,i.e.the blended system possesses the compatibility on thermodynamics.With increasing the content of NC,the glass transition temperature of the blended system shifts downwards.When the mass ratio of NC and PEG in the blended system is 1∶1 ,the blended system reveals a single glass transition temperature.%采用差示扫描量热法(DSC)和动态力学分析法(DMA)研究了不同质量比的硝化棉/聚乙二醇(NC/PEG)共混体系的相容性。结果表明,NC/PEG共混体系中PEG 的熔点、结晶度和结晶熵随 NC 含量的增加明显降低,共混组分相互作用参数χ1,2为负值,即共混体系在热力学上具有相容性。共混体系的玻璃化转变温度随 NC 含量的增加均向低温移动,并且当共混体系中NC与PEG质量比为1∶1时,共混体系呈现单一的玻璃化转变温度。

  10. ncRNA-class Web Tool: Non-coding RNA feature extraction and pre-miRNA classification web tool

    KAUST Repository

    Kleftogiannis, Dimitrios A.

    2012-01-01

    Until recently, it was commonly accepted that most genetic information is transacted by proteins. Recent evidence suggests that the majority of the genomes of mammals and other complex organisms are in fact transcribed into non-coding RNAs (ncRNAs), many of which are alternatively spliced and/or processed into smaller products. Non coding RNA genes analysis requires the calculation of several sequential, thermodynamical and structural features. Many independent tools have already been developed for the efficient calculation of such features but to the best of our knowledge there does not exist any integrative approach for this task. The most significant amount of existing work is related to the miRNA class of non-coding RNAs. MicroRNAs (miRNAs) are small non-coding RNAs that play a significant role in gene regulation and their prediction is a challenging bioinformatics problem. Non-coding RNA feature extraction and pre-miRNA classification Web Tool (ncRNA-class Web Tool) is a publicly available web tool ( http://150.140.142.24:82/Default.aspx ) which provides a user friendly and efficient environment for the effective calculation of a set of 58 sequential, thermodynamical and structural features of non-coding RNAs, plus a tool for the accurate prediction of miRNAs. © 2012 IFIP International Federation for Information Processing.

  11. Modification of structure and optical band-gap of nc-Si:H films with ion irradiation

    Science.gov (United States)

    Zhu, Yabin; Wang, Zhiguang; Sun, Jianrong; Yao, Cunfeng; Shen, Tielong; Li, Bingsheng; Wei, Kongfang; Pang, Lilong; Sheng, Yanbin; Cui, Minghuan; Li, Yuanfei; Wang, Ji; Zhu, Huiping

    2012-09-01

    Hydrogenated nano-crystalline silicon (nc-Si:H) films fabricated by using hot-wire chemical vapor deposition are irradiated at room temperature with 6.0 MeV Xe-ions. The irradiation fluences are 1.0 × 1013, 5.0 × 1013 and 1.0 × 1014 Xe-ions/cm2. The structure and optical band-gap of the irradiated films varying with ion fluence are investigated by means of X-ray diffraction, Raman and UV-Vis-NIR spectroscopes, as well as transmission electron microscopy. It is found that the crystallite size, the crystalline fraction and the optical band-gap decrease continuously with increasing the ion fluence. The crystalline fraction of the films irradiated to the fluences from 0 to 1.0 × 1014 Xe-ions/cm2 decreases from about 65.7% to 2.9% and the optical band-gap decreases from about 2.1 to 1.6 eV. Possible origins of the modification of the nc-Si:H films under 6.0 MeV Xe-ions irradiation are briefly discussed.

  12. Reconstruction of neutrino induced NC-1π{sup 0} using the T2K-ND280 tracker

    Energy Technology Data Exchange (ETDEWEB)

    O’Keeffe, H. M.; Vacheret, A.; Barr, G. D.; Jacob, A.; Williamson, Z. [University of Oxford, Department of Physics, Denys Wilkinson Building, Keble Road, Oxford, OX1 3RH (United Kingdom); Weber, A. [University of Oxford, Department of Physics, Denys Wilkinson Building, Keble Road, Oxford, OX1 3RH (United Kingdom); STFC Rutherford Appleton Laboratory, Harwell, Oxford (United Kingdom)

    2015-05-15

    Single π{sup 0} production is the one of the most important backgrounds in the υ{sub e} appearance measurement in T2K. Large uncertainties in this production make it difficult to predict. Measurement at the near detector (ND280) is required both to constrain the background prediction at the far detector (Super-K) and also at the near detector to improve knowledge of beam υ{sub e} contamination. We present an analysis based on Monte Carlo simulation of neutral current (NC) single π{sup 0} in the tracker region. NC-1π{sup 0} events are selected using a specific two-gamma signature in the tracker region. One decay gamma is reconstructed by selecting an e+/e− pair starting in the Fine-Grained target Detector (FGD) and extending into the TPC, where the leptons can be identified and their momentum measured accurately. The second gamma is then selected in-time in the Calorimeter modules surrounding the tracker. Selections cuts, efficiency and purity of the selection are presented and projection of the expected number of single π{sup 0} candidates for 3 × 10{sup 20} protons on target (PoT) exposure is made.

  13. Mandibuler üçüncü molar dişte idiyopatik kök rezorpsiyonu: vaka raporu

    Directory of Open Access Journals (Sweden)

    Fahrettin Goze

    2011-11-01

    Full Text Available

    Idiopathic resorption is rare form of external resorption, usually with no sign and was generally diagnosed as a chance finding during radiographic examination. This paper describes a rare case of idiopathic external root resorption at apical region of mesial root of mandibular third molar tooth. No significant systemic, dental, or familial findings could be identified as a possible cause.

    ÖZET

    İdiyopatik rezorpsiyon, eksternal rezorpsiyonun nadir görülen bir formudur, genellikle semptomsuzdur ve radyografide tesadüfen teşhis edilir. Bu makalede mandibuler üçüncü molar dişin mezial kökünün apikal bölgesinde gelişen idiyopatik kök rezorpsiyonu vakası sunulmaktadır. Hastanın dişinde rezorpsiyona sebep olabilecek dental veya sistemik bir patolojik durum tespit edilemedi. Ailede böyle bir patolojiye rastlanmadı.

    Anahtar kelimeler: İdiyopatik kök rezorpsiyonu, mandibuler üçüncü molar diş, eksternal rezorpsiyon

  14. Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA

    Directory of Open Access Journals (Sweden)

    Lori Zboray

    2015-12-01

    Full Text Available Spinal and bulbar muscular atrophy (SBMA is a neurodegenerative disease caused by a polyglutamine expansion in the androgen receptor (AR and is associated with misfolding and aggregation of the mutant AR. We investigated the role of an interdomain interaction between the amino (N-terminal FxxLF motif and carboxyl (C-terminal AF-2 domain in a mouse model of SBMA. Male transgenic mice expressing polyQ-expanded AR with a mutation in the FxxLF motif (F23A to prevent the N/C interaction displayed substantially improved motor function compared with N/C-intact AR-expressing mice and showed reduced pathological features of SBMA. Serine 16 phosphorylation was substantially enhanced by the F23A mutation; moreover, the protective effect of AR F23A was dependent on this phosphorylation. These results reveal an important role for the N/C interaction on disease onset in mice and suggest that targeting AR conformation could be a therapeutic strategy for patients with SBMA.

  15. Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.

    Science.gov (United States)

    Zboray, Lori; Pluciennik, Anna; Curtis, Dana; Liu, Yuhong; Berman-Booty, Lisa D; Orr, Christopher; Kesler, Cristina T; Berger, Tamar; Gioeli, Daniel; Paschal, Bryce M; Merry, Diane E

    2015-12-15

    Spinal and bulbar muscular atrophy (SBMA) is a neurodegenerative disease caused by a polyglutamine expansion in the androgen receptor (AR) and is associated with misfolding and aggregation of the mutant AR. We investigated the role of an interdomain interaction between the amino (N)-terminal FxxLF motif and carboxyl (C)-terminal AF-2 domain in a mouse model of SBMA. Male transgenic mice expressing polyQ-expanded AR with a mutation in the FxxLF motif (F23A) to prevent the N/C interaction displayed substantially improved motor function compared with N/C-intact AR-expressing mice and showed reduced pathological features of SBMA. Serine 16 phosphorylation was substantially enhanced by the F23A mutation; moreover, the protective effect of AR F23A was dependent on this phosphorylation. These results reveal an important role for the N/C interaction on disease onset in mice and suggest that targeting AR conformation could be a therapeutic strategy for patients with SBMA.

  16. Topical application of rapamycin ointment ameliorates Dermatophagoides farina body extract-induced atopic dermatitis in NC/Nga mice.

    Science.gov (United States)

    Yang, Fei; Tanaka, Mari; Wataya-Kaneda, Mari; Yang, Lingli; Nakamura, Ayumi; Matsumoto, Shoji; Attia, Mostafa; Murota, Hiroyuki; Katayama, Ichiro

    2014-08-01

    Atopic dermatitis (AD), a chronic inflammatory skin disease characterized by relapsing eczema and intense prurigo, requires effective and safe pharmacological therapy. Recently, rapamycin, an mTOR (mammalian target of rapamycin) inhibitor, has been reported to play a critical role in immune responses and has emerged as an effective immunosuppressive drug. In this study, we assessed whether inhibition of mTOR signalling could suppress dermatitis in mice. Rapamycin was topically applied to inflamed skin in a murine AD model that was developed by repeated topical application of Dermatophagoides farina body (Dfb) extract antigen twice weekly for 7 weeks in NC/Nga mice. The efficacy of topical rapamycin treatment was evaluated immunologically and serologically. Topical application of rapamycin reduced inflammatory cell infiltration in the dermis, alleviated the increase of serum IgE levels and resulted in a significant reduction in clinical skin condition score and marked improvement of histological findings. In addition, increased mTOR phosphorylation in the lesional skin was observed in our murine AD model. Topical application of rapamycin ointment inhibited Dfb antigen-induced dermatitis in NC/Nga mice, promising a new therapy for atopic dermatitis.

  17. Immunosuppressive effects of fisetin against dinitrofluorobenzene-induced atopic dermatitis-like symptoms in NC/Nga mice.

    Science.gov (United States)

    Kim, Gun-Dong; Lee, Seung Eun; Park, Yong Seek; Shin, Dong-Hoon; Park, Gwi Gun; Park, Cheung-Seog

    2014-04-01

    Atopic dermatitis (AD) is a multifactorial chronic skin disorder that is increasing in prevalence globally. In NC/Nga mice, repetitive epicutaneous applications of 2-4-dinitrofluorobenzene (DNFB) induces AD-like clinical symptoms. Bioflanonol fisetin (3,7,3',4'-tetrahydroxyflavone) is a dietary component found in plants, fruits and vegetables. Fisetin has various physiological effects that include anti-oxidation, anti-angiogenesis, anti-carcinogenesis and anti-inflammation. In this study, we investigated whether fisetin relieves AD-like clinical symptoms induced by repeated DNFB treatment in NC/Nga mice. Fisetin significantly inhibited infiltration of inflammatory cells including eosinophils, mast cells and CD4(+) T and CD8(+) T cells, and suppressed the expressions of cytokines and chemokines associated with dermal infiltrates in AD-like skin lesions. Total serum immunoglobulin E (IgE) levels and the ratio of phospho-NF-κB p65 to total NF-κB p65 were markedly reduced by fisetin. Fisetin also reduced the production of interferon-gamma and interleukin-4 by activated CD4(+) T cells in a dose-dependent manner, whereas the anti-inflammatory cytokine, interleukin-10 was increased. These results implicate fisetin as a potential therapeutic for AD.

  18. Pseudoscalar Meson Decay Constants and Couplings, the Witten-Veneziano Formula beyond large N_c, and the Topological Susceptibility

    CERN Document Server

    Shore, G M

    2006-01-01

    The QCD formulae for the radiative decays $\\eta,\\eta'\\to\\c\\c$, and the corresponding Dashen--Gell-Mann--Oakes--Renner relations, differ from conventional PCAC results due to the gluonic $U(1)_A$ axial anomaly. This introduces a critical dependence on the gluon topological susceptibility. In this paper, we revisit our earlier theoretical analysis of radiative pseudoscalar decays and the DGMOR relations and extract explicit experimental values for the decay constants. This is our main result. The flavour singlet DGMOR relation is the generalisation of the Witten-Veneziano formula beyond large $N_c$, so we are able to give a quantitative assessment of the realisation of the $1/N_c$ expansion in the $U(1)_A$ sector of QCD. Applications to other aspects of $\\eta'$ physics, including the relation with the first moment sum rule for the polarised photon structure function $g_1^\\c$, are highlighted. The $U(1)_A$ Goldberger-Treiman relation is extended to accommodate SU(3) flavour breaking and the implications of a mor...

  19. Aspartame Attenuates 2, 4-Dinitrofluorobenzene-Induced Atopic Dermatitis-Like Clinical Symptoms in NC/Nga Mice.

    Science.gov (United States)

    Kim, Gun-Dong; Park, Yong Seek; Ahn, Hyun-Jong; Cho, Jeong-Je; Park, Cheung-Seog

    2015-11-01

    Atopic dermatitis (AD) is a common multifactorial chronic skin disease that has a multiple and complex pathogenesis. AD is gradually increasing in prevalence globally. In NC/Nga mice, repetitive applications of 2, 4-dinitrofluorobenzene (DNFB) evoke AD-like clinical symptoms similar to human AD. Aspartame (N-L-α-aspartyl-L-phenylalanine 1-methyl ester) is a methyl ester of a dipeptide, which is used as an artificial non-nutritive sweetener. Aspartame has analgesic and anti-inflammatory functions that are similar to the function of nonsteroidal anti-inflammatory drugs such as aspirin. We investigated whether aspartame can relieve AD-like clinical symptoms induced by DNFB treatment in NC/Nga mice. Sucrose did not relieve AD-like symptoms, whereas aspartame at doses of 0.5 μg kg(-1) and 0.5 mg kg(-1) inhibited ear swelling and relieved AD-like clinical symptoms. Aspartame inhibited infiltration of inflammatory cells including eosinophils, mast cells, and CD4(+) T cells, and suppressed the expression of cytokines including IL-4 and IFN-γ, and total serum IgE levels. Aspartame may have therapeutic value in the treatment of AD.

  20. The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice

    Directory of Open Access Journals (Sweden)

    Rosa Mistica C. Ignacio

    2013-01-01

    Full Text Available Hydrogen water (HW produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP value and high dissolved hydrogen (DH. It has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, HW effect on atopic dermatitis (AD, an inflammatory skin disorder, is poorly documented. In the present study, we examined the immunological effect of drinking HW on Dermatophagoides farinae-induced AD-like skin in NC/Nga mice. Mice were administered with HW and purified water (PW for 25 days. We evaluated the serum concentration of pro-inflammatory (TNF-α, Th1 (IFN-γ, IL-2, and IL-12p70, Th2 (IL-4, IL-5, and IL-10, and cytokine expressed by both subsets (GM-CSF to assess their possible relationship to the severity of AD. The serum levels of cytokines such as IL-10, TNF-α, IL-12p70, and GM-CSF of mice administered with HW was significantly reduced as compared to PW group. The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice. This is the first note on the drinking effect of HW on AD, clinically implying a promising potential remedy for treatment of AD.

  1. 3-D Flow Field of Cathode Design for NC Precision Electrochemical Machining Integer Impeller Based on CFD

    Directory of Open Access Journals (Sweden)

    Rui Wu

    2011-09-01

    Full Text Available In order to achieve high efficiency and low cost cathode designing, improve stability of process in NC precision electrochemical machining of integer impeller, a method of applying Computational Fluid Dynamics (CFD to aid designing flow field structure of cathode and parameters for NC-ECM has been proposed in this study. The designing of flow field is the key point in cathode design and a suitable flow field design guarantees the process stability in electrochemical machining. A numerical model of the three-dimension flow field was built according to the geometrical model of interelectrode gap and cathode outline. Then the numerical simulation of 3-D flow field was performed by using the standard k-, turbulence model when the turbulence state in electrochemical machining had been determined. The effect of cathode’s structure and initial electrolyte pressure on the electrolyte flow field was analyzed according to the results of numerical simulation. A series of results similar to the actual experimental results are obtained. The method deduced in this paper could be used to achieve high efficiency and low cost cathode design, select of initial electrolyte pressure, and consequently a lot of “trial and error” cycles will be deduced.

  2. 稳定剂对ADN和NC初期相互作用的影响%Influences of Stabilizers on the Nascent Interaction between ADN and NC

    Institute of Scientific and Technical Information of China (English)

    李吉祯; 王祎; 刘芳莉; 付小龙; 樊学忠; 张腊莹; 王琼

    2011-01-01

    在研究二硝酰胺铵(ADN)的热行为特性及其与硝化纤维素(NC)相互作用的基础上,利用差示扫描量热法(DSC)研究了稳定剂N-甲基对硝基苯胺(MNA)、二号中定剂(C2)、2-硝基二苯胺(2-NDPA)、六次甲基四胺(HMT)及其复配体系(MNA/C2、MNA/2-NDPA、MNA/HMT)对ADN与NC之间初期相互作用的影响.结果表明,稳定剂MNA和C2可使ADN与NC之间的相互作用得到一定程度的减弱,MNA与C2、2-NDPA和HMT的复配协同作用对ADN与NC之间的初期相互作用产生了较为明显的抑制作用,与NC/ADN二元混合体系相比,NC/(ADN/稳定剂)体系的DSC峰温提前量可由19.2℃缩减至11.9℃.%On the basis of the study of thermal behavior of ammonium dinitramide (ADN) and the interaction between ADN and NC, the influences of stabilizers, such as N-methyl-p-nitroaniline(MNA), 1,3-dimethyl-1,3-diphenylurea(C2 ) ,2-nitrodianiline(2-NDPA) ,hexamethylenetetramine(HMT) and its complex MNA/C2, MNA/2-NDPA and MNA/HMT, on the nascent interactions between ADN and NC were investigated by using the method of DSC.The results show that the interaction between ADN and NC can be decreased to a certain extent by mixing MNA and C2, and the nascent interaction between ADN and NC can be inhibited obviously by mixing the complex of MNA/C2, MNA/2-NDPA and MNA/HMT. Comparing the binary system of ADN/NC, the value of △Tp,which is the DSC exothermic peak temperature different between ADN/stabilizer and NC, can be decreased from 19. 2℃ to 11.9 ℃ by using the mixtures of stabilizers.

  3. Effects of stable aqueous fullerene nanocrystal (nC60) on Daphnia magna:Evaluation of hop frequency and accumulations under different conditions

    Institute of Scientific and Technical Information of China (English)

    Xianji Tao; Yiliang He; Bo Zhang; Yongsheng Chen; Joseph B. Hughes

    2011-01-01

    We investigated the effects of environmental factors and properties of water-stable crystal fullerene (nC60) on the uptake of nC60 by Daphnia magna based on known accumulation in our laboratory. This study was performed for seven days using different environmental factors including temperature, pH, water hardness, concentration (density of particle), and particle size. Results demonstrated that body burden of C60 increased with time in all experiments. Body burden of C60 increased with increasing concentration and particle size, and uptake of particles >100 nm reached their maximums more quickly than those <100 nm. Under high hardness in aqueous systems with lower pH and high temperature, uptake was higher than those under opposite conditions. Uptake in all batch tests reached balance within five days. Both nC60 properties and environmental factors influenced uptake of nC60 by D.magna in an aqueous system. Additionally, environmental factors may have affected accumulation by changing nC60 properties, which are critical to understand the accumulation of fullerenes in aqueous systems.

  4. Quantification of Valleys of Randomly Textured Substrates as a Function of Opening Angle: Correlation to the Defect Density in Intrinsic nc-Si:H.

    Science.gov (United States)

    Kim, Do Yun; Hänni, Simon; Schüttauf, Jan-Willem; van Swaaij, René A C M M; Zeman, Miro

    2016-08-17

    Optical and electrical properties of hydrogenated nanocrystalline silicon (nc-Si:H) solar cells are strongly influenced by the morphology of underlying substrates. By texturing the substrates, the photogenerated current of nc-Si:H solar cells can increase due to enhanced light scattering. These textured substrates are, however, often incompatible with defect-less nc-Si:H growth resulting in lower Voc and FF. In this study we investigate the correlation between the substrate morphology, the nc-Si:H solar-cell performance, and the defect density in the intrinsic layer of the solar cells (i-nc-Si:H). Statistical surface parameters representing the substrate morphology do not show a strong correlation with the solar-cell parameters. Thus, we first quantify the line density of potentially defective valleys of randomly textured ZnO substrates where the opening angle is smaller than 130° (ρSi:H (ρdefect), which is obtained by fitting external photovoltaic parameters from experimental results and simulations. We confirm that when ρ<130 increases the Voc and FF significantly drops. It is also observed that ρdefect increases following a power law dependence of ρ<130. This result is attributed to more frequently formed defective regions for substrates having higher ρ<130.

  5. Study on the Ecological Adaptability of Flue-cured Tobacco Variety NC297 from American in Different Altitude%美引烤烟品种NC297不同海拔生态适应性研究

    Institute of Scientific and Technical Information of China (English)

    徐益群; 田育天; 张留臣; 普云飞; 常剑; 胡保文; 瞿兴; 李迪秦

    2013-01-01

      为探究美引烤烟品种NC297不同海拔高度的生态适应性,展开连续多年多点的试验示范研究。结果表明,NC297在不同海拔的适应性广,烟叶产量(其产量为2016~2562 kg/hm2)、抗性、品质等主要农艺性状较为协调兼顾,与其原生地表现相似。该品种具有耐肥性较好、抗病性较强、优质适产和易烘烤等特点,烟叶外观质量综合评分高,糖碱比和两糖差值较为合理。在香气的甜韵感和丰富性方面表现优于对照品种K326和‘云烟87’,吸食品质彰显清香型风格,是适宜于在1600~1800 m中海拔地区的中等肥力以上土壤种植和大面积推广的优良品种,最适宜种植密度为15000~16500株/hm2,最佳施肥比例为N:P2O5:K2O=1:1:3,施氮量田烟N 105~135 kg/hm2、地烟N 75~105 kg/hm2。%In order to explore the ecological adaptability of the variety tobacco NC297 in different altitude, the continuous many years of the demonstration experiments with multiple spots were carried. The results showed that the NC297 had an extensive ecological adaptability in different altitude, and it had only better tobacco coordination with its leaves output from 2016 to 2562 kg/hm2, resistance, quality and other agronomic traits similar to the performance of their original habitat, but a better resistance to fertilizers, strong disease resistance, high quality and appropriate output, easy to baking, high synthetic score of the appearance quality, a ratio of sugar and nicotine and a better radio of total sugar and reducing sugar also. It had better aroma of sweet rhyme and richness than that of the check varieties K326 and‘Yunyan 87’. It was a better suck quality with its qing scent style deserving to popularization in the medium or above fertility soil from altitude 1600 to 1800 m. The most suitable planting density was from 15000 to 16500 plants/hm2, the suitable fertilizer ratio of N, P2O5 and K2O was one to one to

  6. Design and Implementation of VC-based NC Code Interpreter and Its Extension for Open NC System%基于VC的开放式数控系统NC代码解释器及扩展功能的设计及实现

    Institute of Scientific and Technical Information of China (English)

    高静远; 张鹏; 周金瑞

    2012-01-01

    以Microsoft Visual C++6.0为工具开发出一款NC代码解释器,实现了NC代码读取、检错、解释、基本插补计算和刀路显示等功能,阐述了其设计及实现方法,添加了控制信号输出功能,并通过实验检验了NC代码解释器的可行性.%A kind of NC code interpreter developed on Microsoft Visual C + +6.0 and its designing method were introduced. This VC-based NC code interpreter could be used to read NC file, check NC code and translate NC code into corresponding data. Besides, elementary interpolation calculation function and tool path displaying function were included in this software. A control signal output module was added to the software and the feasibility of the NC code interpreter was tested through experiment.

  7. Tat peptide-admixed elastic liposomal formulation of hirsutenone for the treatment of atopic dermatitis in Nc/Nga mice

    Directory of Open Access Journals (Sweden)

    Kang MJ

    2011-10-01

    Full Text Available Myung Joo Kang1, Jae Yoon Eum1, Mi Sook Jeong2, Sang Han Park1, Ki Young Moon1, Mean Hyung Kang1, Min Soo Kim1, Sun Eun Choi1, Min Won Lee1, Do Ik Lee1, Hyoweon Bang2, Chung Soo Lee2, Seong Soo Joo3, Kapsok Li2, Mi-Kyung Lee2, Seong Jun Seo2, Young Wook Choi11College of Pharmacy, ChungAng University, Heuksuk-dong, Dongjak-gu, Seoul, 2College of Medicine, Chung-Ang University, Heuksukdong, Dongjak-gu, Seoul, 3Division of Marine Molecular Biotechnology, Gangneung-Wonju National University, Gangneung, South KoreaBackground: The aim of the present study was to enhance a topical delivery of hirsutenone (HST, a naturally occuring immunomodulator, employing Tat peptide-admixed elastic liposomes (EL/T.Methods: HST-loaded EL, consisting of phosphatidylcholine and Tween 80 (85:15 w/w%, were prepared using thin film hydration method. By adding Tat peptide to EL (0.16 w/w%, EL/T were formulated. The in vitro skin permeation of HST was examined using a Franz diffusion cell mounted with depilated mouse skin. Lesions for atopic dermatitis (AD were induced by a topical application of diphenylcyclopropenone to NC/Nga mice. Therapeutic improvements of AD were evaluated by clinical skin severity scores. Immunological analyses on inducible nitric oxide synthase and cyclooxygenase-2 levels in the skin and interleukin (IL-4, IL-13, immunoglobulin E, and eosinophil levels in the blood were also performed.Results: EL systems were superior to conventional cream, revealing greater flux values in a permeation study. The addition of Tat peptide further increased the skin permeation of HST. In an efficacy study with AD-induced NC/Nga mice, an HST-containing EL/T formulation brought a significant improvement in both skin severity score and immune-related responses for the levels of nitric oxide synthase, cyclooxygenase-2, IL-4, IL-13, immunoglobulin E, and eosinophils.Conclusion: A novel EL/T formulation was successfully developed for topical delivery of HST to treat AD

  8. Reversal Effect and Mechanisms of Recombinant Human Tumor Necrosis Factor-NC Against the Doxorubicin Resistance in Leukemia K562/Doxorubicin Cells

    Institute of Scientific and Technical Information of China (English)

    ZHOU Jing-hong; CHEN Bo-hua

    2015-01-01

    Objective: To explore the reversal effect and mechanisms of recombinant human tumor necrosis factor-NC (rhTNF-NC) against the doxorubicin (Dox) resistance in chronic myelogenous leukemia (CML) K562/Dox cells. Methods: The chemo-sensitivity of tumor cells dealt with different concentrations of rhTNF-NC to Dox was detected by tetrazolium dye assay (MTT). The intra-cellular Dox accumulation represented by lfuorescence intensity was determined by lfow cytometry (FCM) at the excitation wave length of 488 nm and emission wave length of 550 nm. The expression of multidrug resistance (MDR)-related genes and proteins was analyzed by reverse transcription polymerase chain reaction (RT-PCR) and Western blot assays. Results:After being exposed to gradually increasing concentrations of Dox for 10 consecutive months, K562/Dox cells were more resistant to Dox (nearly 132 times) than Dox-sensitive K562 cells. The IC50 of Dox for K562 and K562/Dox cells were (0.04±0.01) and (5.55±0.08) μmol/L, respectively. When K562/Dox cells were treated with rhTNF-NC at 500, 2 500 or 5 000U/mL, the IC50 of Dox was decreased to (2.22±0.34), (1.41±0.13) and (1.04±0.09) μmol/L, respectively. The concentration-response curves were moved upward by the treatment of rhTNF-NC (P Conclusion: rhTNF-NC can effectively augment the drug accumulation in tumor cells. This is due to the up-regulation of TopoIIα and down-regulation of MDR1, MRP and GSTπ at mRNA expression as well as reduction of P-gp and PKCα expression.

  9. Effect of vaccination of cattle with the low virulence Nc-Spain 1H isolate of Neospora caninum against a heterologous challenge in early and mid-gestation.

    Science.gov (United States)

    Rojo-Montejo, Silvia; Collantes-Fernández, Esther; Pérez-Zaballos, Francisco; Rodríguez-Marcos, Sonia; Blanco-Murcia, Javier; Rodríguez-Bertos, Antonio; Prenafeta, Antoni; Ortega-Mora, Luis Miguel

    2013-11-01

    Live vaccines have emerged as one of the most potentially cost-effective measures for the control of bovine neosporosis. Previous studies have shown that Nc-Spain 1H is a naturally attenuated isolate of Neospora caninum and that immunisation with live Nc-Spain 1H tachyzoites generated a protective immune response in mice. The aim of this study was to evaluate the safety and efficacy of immunisation in cattle. N. caninum-seronegative heifers were immunised subcutaneously twice with 107 live Nc-Spain 1H tachyzoites prior to artificial insemination. No adverse reactions or negative effects on reproductive parameters were recorded following immunisation. In immunised and non-challenged heifers, no foetal deaths were observed, and none of the calves was congenitally infected. The efficacy against N. caninum-associated foetal death and vertical transmission was determined after challenge with high doses of the Nc-1 isolate at 70 and 135 days of gestation, respectively. After the challenge in early gestation, the immunisation induced a protection of 50% against foetal death. In addition, the microsatellite analysis performed in PCR-positive tissue samples from foetuses that died after challenge infection showed that the profiles corresponded to the challenge isolate Nc-1. A degree of protection against vertical transmission was observed after challenge at mid-gestation; calves from immunised heifers showed significantly lower pre-colostral Neospora-specific antibody titres than calves from the non-immunised/challenge group (P < 0.05). Strong antibody and interferon gamma responses were induced in the immunised heifers. This study indicates that the immunisation before pregnancy with the Nc-Spain 1H vaccine isolate appeared to be safe and reduced the occurrence of N. caninum-associated abortion and vertical transmission in experimentally infected cattle. In light of these encouraging results, the next step for testing this live attenuated candidate should be the assessment

  10. Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis.

    Science.gov (United States)

    Netzer, K O; Suzuki, K; Itoh, Y; Hudson, B G; Khalifah, R G

    1998-06-01

    Type IV collagen alpha1-alpha6 chains have important roles in the assembly of basement membranes and are implicated in the pathogenesis of Goodpasture syndrome, an autoimmune disorder, and Alport syndrome, a hereditary renal disease. We report comparative sequence analyses and structural predictions of the noncollagenous C-terminal globular NC1 domain (28 sequences). The inferred tree verified that type IV collagen sequences fall into two groups, alpha1-like and alpha2-like, and suggested that vertebrate alpha3/alpha4 sequences evolved before alpha1/alpha2 and alpha5/alpha6. About one fifth of NC1 residues were identified to confer either the alpha1 or alpha2 group-specificity. These residues accumulate opposite charge in subdomain B of alpha1 (positive) and alpha2 (negative) sequences and may play a role in the stoichiometric chain selection upon type IV collagen assembly. Neural network secondary structure prediction on multiple aligned sequences revealed a subdomain core structure consisting of six hydrophobic beta-strands and one short alpha-helix with a significant hydrophobic moment. The existence of opposite charges in the alpha-helices may carry implications for intersubdomain interactions. The results provide a rationale for defining the epitope that binds Goodpasture autoantibodies and a framework for understanding how certain NC1 mutations may lead to Alport syndrome. A search algorithm, based entirely on amino acid properties, yielded a possible similarity of NC1 to tissue inhibitor of metalloproteinases (TIMP) and prompted an investigation of a possible functional relationship. The results indicate that NC1 preparations decrease the activity of matrix metalloproteinases 2 and 3 (MMP-2, MMP-3) toward a peptide substrate, though not to [14C]-gelatin. We suggest that an ancestral NC1 may have been incorporated into type IV collagen as an evolutionarily mobile domain carrying proteinase inhibitor function.

  11. Theoretical maximum performance evaluation of third generation silicon solar cell consisting of nc-Si:H/a-Si:H quantum wells

    Science.gov (United States)

    Tripathi, Brijesh; Sircar, Ratna

    2016-09-01

    The maximum performance of nc-Si:H/a-Si:H quantum well solar cell is theoretically evaluated by studying the spectral absorption of incident radiation with respect to the number of inserted nc-Si:H quantum well layers. Fundamental intrinsic properties of a-Si:H and nc-Si:H materials reported in literature have been used to evaluate the performance parameters. Enhanced spectral absorption is recorded due to insertion of nc-Si:H quantum well layers in the intrinsic region of a-Si:H solar cell. By inserting 50 QW layers of nc-Si:H in the intrinsic region of the a-Si:H solar cell, the short-circuit current density (JSC) increases by ∼100% as compared to the baseline whereas the open-circuit voltage (VOC) decreases by ∼38%. The decrease in VOC is explained on the basis of quasi-Fermi level separation under the illuminated state of solar cell. Theoretical maximum efficiency, having the combined effect of the increase in JSC and decrease in VOC, has increased by ∼24% in comparison with the baseline due to the use of QW as calculated using ideal carrier lifetime value. With a realistic carrier lifetime of the state-of-the-art a-Si:H solar cells, the addition of QWs do not yield any significant gain. From this study, it is concluded that a high carrier lifetime is required to gain a noteworthy benefit from the nc-Si:H/a-Si:H QWs.

  12. Sputtered neutral Si nC m clusters as a monitor for carbon implantation during C 60 bombardment of silicon

    Science.gov (United States)

    Wucher, A.; Kucher, A.; Winograd, N.; Briner, C. A.; Krantzman, K. D.

    2011-06-01

    The incorporation of carbon atoms into a silicon surface under bombardment with 40-keV C60+ ions is investigated using time-of-flight mass spectrometry of sputtered neutral and ionized Si nC m clusters. The neutral particles emitted from the surface are post-ionized by strong field infrared photoionization using a femtosecond laser system operated at a wavelength of 1400/1700 nm. From the comparison of secondary ion and neutral spectra, it is found that the secondary ion signals do not reflect the true partial sputter yields of the emitted clusters. The measured yield distribution is interpreted in terms of the accumulating carbon surface concentration with increasing C 60 fluence. The experimental results are compared with those from recent molecular dynamics simulations of C 60 bombardment of silicon.

  13. Mechano-chemical manipulation of Sn chains on Si(1 0 0) by NC-AFM

    Science.gov (United States)

    Sweetman, A.; Lekkas, I.; Moriarty, P.

    2017-02-01

    We investigate the atomic structure of Sn dimer chains grown on the Si(1 0 0) surface using non-contact atomic force microscopy (NC-AFM) at cryogenic temperatures. We find that similar to the native Si(1 0 0) dimer structure, the ground state of the Sn dimer structure is buckled at low temperature. At 5 K we show that the buckling state of the Sn dimers may be controllably, and reversibly, manipulated with atomic precision by close approach of the tip, without modification of the underlying substrate buckling structure. At intermediate cryogenic temperatures we observe changes in the configuration of the dimer chains in the region where the tip-sample interaction is very weak, suggesting that the energy barrier to transit between configurations is sufficiently small to be surmounted at 78 K.

  14. Structural Characterization of N-Alkylated Twisted Amides: Consequences for Amide Bond Resonance and N-C Cleavage.

    Science.gov (United States)

    Hu, Feng; Lalancette, Roger; Szostak, Michal

    2016-04-11

    Herein, we describe the first structural characterization of N-alkylated twisted amides prepared directly by N-alkylation of the corresponding non-planar lactams. This study provides the first experimental evidence that N-alkylation results in a dramatic increase of non-planarity around the amide N-C(O) bond. Moreover, we report a rare example of a molecular wire supported by the same amide C=O-Ag bonds. Reactivity studies demonstrate rapid nucleophilic addition to the N-C(O) moiety of N-alkylated amides, indicating the lack of n(N) to π*(C=O) conjugation. Most crucially, we demonstrate that N-alkylation activates the otherwise unreactive amide bond towards σ N-C cleavage by switchable coordination.

  15. Seroprevalence of antibody to NcSAG1 antigen of Neospora caninum in cattle from Western Java, Indonesia.

    Science.gov (United States)

    Ichikawa-Seki, Madoka; Guswanto, Azirwan; Allamanda, Puttik; Mariamah, Euis Siti; Wibowo, Putut Eko; Nishikawa, Yoshifumi

    2016-01-01

    Neospora caninum can cause fetal abortion and neonatal mortality in cattle, and is a cause of economic concern worldwide. This study aimed to determine the prevalence of Neospora caninum-specific antibodies in cattle from Western Java, Indonesia. Serum samples from 991 cattle from 21 locations were tested for antibodies to N. caninum by using an enzyme-linked immunosorbent assay (ELISA) on the basis of recombinant NcSAG1. The overall seroprevalence was 16.6%, ranging from 0 to 87.5% in the sampled locations. The results of this study indicate latent infection rates of sampled animals were different in each location. Further studies are necessary to elucidate the relationship between N. caninum infection and abortion in cattle, and to identify risk factors for infection in high-prevalence environments.

  16. Allergic airway inflammation by nasal inoculation of particulate matter (PM2.5 in NC/Nga mice.

    Directory of Open Access Journals (Sweden)

    Keiki Ogino

    Full Text Available To evaluate the effect of airborne particulate matter 2.5 (PM2.5 in winter on airway inflammation, water-soluble supernatant (Sup and water-insoluble precipitate (Pre in PM2.5 were inoculated in NC/Nga mice with high sensitivity to mite allergens. Sup with aluminum oxide was injected intraperitoneally for sensitization. Five days later, Sup, Pre or both Sup and Pre were inoculated via the nasal route five times for more sensitization and a challenge inoculation on the 11th day in NC/Nga mice. On the 12th day, mice were examined for airway hyperresponsiveness (AHR, BALF cell count and IL-1β concentration, mRNA expression of Th1 and Th2 cytokines, chemokines such as eotaxin 1 and eotaxin 2, inflammasomal complex molecules such as IL-1β, caspase 1 and the nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3 in lung tissue as well as histopathology. The synergistic effect of Sup and Pre was observed in terms of increases in AHR, BALF cells, the mRNA expression of IL-13, eotaxin1 and IL-1β, and the IL-1β concentration in BALF. Intracellular deposits of insoluble particulates were observed in macrophages around inflammatory granulation of the mouse group treated with Sup and Pre. These results suggest that PM2.5 can induce airway hyperresponsiveness in mice with genetically high sensitivity to mite allergens by an inflammasome-associated mechanism and synergistic action of insoluble particulates and soluble components.

  17. Is distance to chemotherapy an obstacle to adjuvant care among the N.C. Medicaid—enrolled colon cancer patients?

    Science.gov (United States)

    Song, Eunyoung; Klepin, Heidi D.; Foley, Kristie L.

    2016-01-01

    Background Adjuvant chemotherapy for colon cancer has been linked to patient and provider characteristics but little is known about whether distance to chemotherapy providers constitutes an obstacle to chemotherapy. Methods A total of 1,184 Medicaid patients diagnosed with colon cancer in North Carolina in 1999–2002 comprised the sample. Data from the N.C. Central Cancer Registry, N.C. Medicaid Claims, American Hospital Directory and US Census were merged. Logistic regression models were used to estimate the association between chemotherapy receipt and the distance to nearest chemotherapy provider. Results Compared to the referent group of SEER-staged II (local) cancer patients living less than 2 miles from the nearest chemotherapy provider, the odds of receiving chemotherapy fell as the distance to the nearest provider increased. The odds ratio (OR) for those living ≥5 to <15 miles away was 0.13 [95% confidence intervals (CI), 0.04–0.39], and OR for those living ≥15 miles away was 0.06 (95% CI, 0.01–0.52). Patients diagnosed with regional, SEER-staged III (regional) cancer were less likely to receive chemotherapy if they lived in rural areas more than 20 miles away from the nearest provider (OR =0.08; 95% CI, 0.01–0.72). However, we found no evidence of association between chemotherapy receipt and distance to the nearest provider for regional cancer patients living in urban areas and those living in rural areas within 20 miles from the nearest chemotherapy provider. Conclusions Distance to provider may be an obstacle to chemotherapy for some groups of low-income colon cancer patients. Relieving travel burdens of rural patients living far from providers may help Medicaid increase guideline-consistent adjuvant care for regional cancer patients. PMID:27284464

  18. Effect of 750 keV Argon ion irradiation on nc ZnO−SiO{sub x} thin films

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, V.V. Siva, E-mail: vvsk@iuac.res.in

    2015-10-01

    Nanocomposite (nc) ZnO−SiO{sub x} thin films were grown using rf magnetron sputter deposition technique and post-deposition annealing at 750 °C. These films were irradiated with 750 keV Argon ions at fluences in the range from 1 × 10{sup 15} to 1 × 10{sup 17} ions/cm{sup 2}, using Low Energy Ion Beam Facility (LEIBF) at IUAC. X-ray diffraction (XRD) patterns of the as-deposited irradiated films show decrease in intensity of ZnO peaks relative to pristine film. Fourier transform infrared (FT-IR) spectroscopy measurements of the as-deposited irradiated films indicate the breakage of Zn−O, Zn−O−Si and Si−O−Si bonds in them, which is substantiated by FT-IR measurements of 750 °C annealed films that were irradiated at a fluence of 10{sup 16} ions/cm{sup 2}. Photoluminescence (PL) measurements show drastic decrease of visible PL emission from as-deposited irradiated films. Current−Voltage (I–V) measurements show decrease in surface resistance of irradiated films by three orders of magnitude. The results suggest that 750 keV argon ion irradiation of nc ZnO−SiO{sub x} films has resulted in the formation of non-radiative defects in ZnO phase and damage in SiO{sub x}, and amorphization in Zinc silicate phase. These results are explained on the basis of the dominant energy loss mechanism of low energy ions in materials.

  19. Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

    Directory of Open Access Journals (Sweden)

    In Jun Yang

    2016-01-01

    Full Text Available Valencene (VAL isolated from Cyperus rotundus possesses various biological effects such as antiallergic and antimelanogenesis activity. We investigated the effect of VAL on atopic dermatitis (AD skin lesions and their molecular mechanisms. We topically applied VAL to 1-chloro-2,4-dinitrobenzene (DNCB sensitized NC/Nga mice. Modified scoring atopic dermatitis index, scratching behavior, and histological/immunohistochemical staining were used to monitor disease severity. RT-PCR, western blotting, and enzyme-linked immunosorbent assay were used to determine the level of IgE, proinflammatory cytokines/chemokines production, and skin barrier proteins expression. Topical application of VAL significantly reduced AD-like symptoms and recovered decreased expression of filaggrin in DNCB-sensitized NC/Nga mice. The levels of serum IgE, IL-1β, IL-6, and IL-13 in skin/splenic tissue were reduced. In vitro studies using TNF-α and IFN-γ treated HaCaT cells revealed that VAL inhibited the exaggerated expression of Th2 chemokines including TARC/CCL17, MDC/CCL22, and proinflammatory chemokines such as CXCL8, GM-CSF, and I-CAM through blockade of the NF-κB pathway. In addition, expression of the skin barrier protein, involucrin, was also increased by VAL treatment. VAL inhibited the production and expression of proinflammatory cytokines IL-1β and IL-6 in LPS-stimulated RAW 264.7 cells. These results suggest that VAL may serve as a potential therapeutic option for AD.

  20. An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs.

    Directory of Open Access Journals (Sweden)

    Ru Huang

    Full Text Available Imprinted macro non-protein-coding (nc RNAs are cis-repressor transcripts that silence multiple genes in at least three imprinted gene clusters in the mouse genome. Similar macro or long ncRNAs are abundant in the mammalian genome. Here we present the full coding and non-coding transcriptome of two mouse tissues: differentiated ES cells and fetal head using an optimized RNA-Seq strategy. The data produced is highly reproducible in different sequencing locations and is able to detect the full length of imprinted macro ncRNAs such as Airn and Kcnq1ot1, whose length ranges between 80-118 kb. Transcripts show a more uniform read coverage when RNA is fragmented with RNA hydrolysis compared with cDNA fragmentation by shearing. Irrespective of the fragmentation method, all coding and non-coding transcripts longer than 8 kb show a gradual loss of sequencing tags towards the 3' end. Comparisons to published RNA-Seq datasets show that the strategy presented here is more efficient in detecting known functional imprinted macro ncRNAs and also indicate that standardization of RNA preparation protocols would increase the comparability of the transcriptome between different RNA-Seq datasets.

  1. 复杂曲面的数控加工误差分析%Error Analysis of the Complex Surface NC Machining

    Institute of Scientific and Technical Information of China (English)

    王振; 韩祥凤

    2011-01-01

    针对复杂曲面的多轴数控加工,应用数学知识建模,从理论上分析了平底铣刀刀具加工复杂曲面时的误差,得出了影响数控加工精度的主要因素并提出了误差补偿方法,为控制多轴数控加工的误兰提供了理论依据与补偿算法,对高精度复杂曲面的数控加工具有借鉴意义.%Complex surfaces are normally manufactured with multi-axis NC machining tools, This paper has applied the mathematical modeling and analyzed the occurring error when the flat milling cutter machining the complex surface in theory. The author found the main reasons affecting the accuracy of NC machining, proposed the method to compensate the error and provided a theoretical basis and the compensation algorithm for the control of multi-axis NC machining, which has the enlightenment to NC machining of the complex curve surface.

  2. Combined TEM and NC-AFM study of Al2O3-supported Pt nanoparticles

    DEFF Research Database (Denmark)

    Jensen, Thomas Nørregaard; Simonsen, Søren Bredmose; Chorkendorff, Ib

    on planar, amorphous Al2O3. Characterization of the size and shape of the Pt nanoparticles has been done by combining transmission electron microscopy (TEM) and non-contact atomic force microscopy (NC-AFM), because of the great complementarity between these techniques. TEM measurements very accurately give...

  3. NC Sharpening of Cutter with Space Angles%空间复合角度刀具的数控刃磨

    Institute of Scientific and Technical Information of China (English)

    张渤; 李国琴; 张世昌

    2001-01-01

    本文以气门口锪铰刀为例,介绍了空间复合角度刀具数控刃磨的一般方法。%Taking the double cone hole reamer as an example,the general method for NC sharpening of cuter with space angles is introduced in this paper

  4. Improved large $N_c$ parametrizations of the $\\gamma^\\ast N \\to \\Delta(1232)$ quadrupole form factors and the Siegert's theorem

    CERN Document Server

    Ramalho, G

    2016-01-01

    The large $N_c$ limit provides relations that can be used to calculate the $\\gamma^\\ast N \\to \\Delta(1232)$ quadrupole form factors at low and intermediate $Q^2$ under the assumption of the pion cloud dominance. There are two limitations in those parametrizations. First, the parametrization of the Coulomb quadrupole form factor underestimate the low $Q^2$ data. Second, when extrapolated for the timelike region, the form factors violate the Siegert's theorem by terms of the order $1/N_c^2$. We propose here corrections to the parametrization of the electric quadrupole form factor, which violate the Siegert's theorem only by terms of the order $1/N_c^4$. Combining the improved large $N_c$ pion cloud parametrizations with the valence quark contributions based on a covariant quark model for the quadrupole transition form factors, we obtain an extrapolation to the timelike region consistent with the Siegert's theorem, and accomplish also a very good description of the data.

  5. Electronic Publishing, Scientific Communication and Libraries Elektronik Yayıncılık, Bilimsel İletişim ve Kütüphaneler

    Directory of Open Access Journals (Sweden)

    Yaşar Tonta

    1997-12-01

    Full Text Available This article deals with the electronic publishing and scientific communication and discusses, from various aspects, the impact of electronic publishing on libraries. It examines the technological, economic and legal problems which impede the implementation of a totally electronic environment for scientific communication. The impact of electronic publishing on libraries is discussed from the view points of, inter alia, information retrieval, indexing, dissemination of information through secondary reference sources and archiving. Bu makalede elektronik yayıncılık ve bilimsel iletişim konusu incelenmekte ve elektronik yayıncılığın kütüphaneler üzerindeki etkileri tartışılmaktadır. Elektronik yayıncılığın tarihçesine kısaca değinilmekte ve tamamen elektronik olarak bilimsel iletişimin sağlanmasını engelleyen teknolojik, ekonomik ve yasal sorunlar gözden geçirilmektedir. Elektronik yayıncılığın kütüphaneler üzerindeki muhtemel etkileri ise bilgi erişim, dizinleme, ikincil kaynaklar aracılığıyla duyurma ve arşivleme gibi yönlerden ele alınarak incelenmektedir.

  6. 基于数控加工的三维仿真系统设计%3D Simulation System Design Based on NC Machining

    Institute of Scientific and Technical Information of China (English)

    王秋鹏; 刘宏利

    2012-01-01

    Taking Windows system as the development platform, and with the auxiliary tool of OpenGL, the NC, CNC milling, drilling and processing of 3D simulation system were realized. The system was composed of NC program edit, real-ized NC program examination and interpretation, and also realized the simulation calculation and simulation display module, the specific features of NC code of the reverse simulation, and the actual turning, milling and drilling process is very close, and has strong practical significance and function.%以Windows系统为研发平台,辅助OpenGL工具,实现了数控车、数控铣、钻加工的三维仿真系统.该系统由数控程序编辑而成,建立了数控程序的检查和解释、仿真计算以及仿真显示等模块,具有数控代码反向仿真的特点,与实际的车削、铣削以及钻削加工过程十分贴近,具有较强的现实意义和作用.

  7. Tribological properties of nc-TiC/a-C : H coatings prepared by magnetron sputtering at low and high ion bombardment of the growing film

    NARCIS (Netherlands)

    Souček, Pavel; Schmidtová, Tereza; Buršíková, Vilma; Vašina, Petr; Pei, Y.T.; Hosson, J.Th.M. De; Caha, Ondřej; Peřina, Vratislav; Mikšová, Romana; Malinský, Petr

    2014-01-01

    Two series of nc-TiC/a-C:H coatings were deposited by a hybrid PVD–PECVD process of titanium sputtering in argon/acetylene atmosphere at two configurations of magnetic field resulting in different impinging ion fluxes on the growing film. The composition of the coatings was varied by changing the ac

  8. Quark-Antiquark and Diquark Condensates in Vacuum in Two-Flavor Four-Fermion Interaction Models with Any Color Number Nc

    Institute of Scientific and Technical Information of China (English)

    ZHOU Bang-Rong

    2009-01-01

    The color number No-dependence of the interplay between quark-antiquark condensates and diquark condensates in vacuum in two-flavor four-fermion interaction models is researched. The results show that the Gs-Hs (the coupling constant of scalar (qq)2-scalar (qq)2 channel) phase diagrams will be qualitatively consistent with the case of Nc = 3 as Nc varies in 4D Nambu-Jona-Lasinio model and 2D Gross-Neveu (GN) model. However, in 3D GN model, the behavior of the Gs-Hp (the coupling constant of pseudoscalar (qq)2 channel) phase diagram will obviously depend on No. The known characteristic that a 3D GN model does not have the coexistence phase of the eondensates and is proven to appear only in the ease of Nc≤ 4. In all the models, the regions occupied by the phases containing the diquark condensates in corresponding phase diagrams will gradually decrease as Nc grows up and finally go to zero if Nc →∞, i.e. in this limit only the pure phase could exist.

  9. NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo

    Directory of Open Access Journals (Sweden)

    Harada M

    2012-05-01

    Full Text Available Mitsunori Harada,1 Caname Iwata,2 Hiroyuki Saito,1 Kenta Ishii,1 Tatsuyuki Hayashi,1 Masakazu Yashiro,3 Kosei Hirakawa,3 Kohei Miyazono,2 Yasuki Kato,1 Mitsunobu R Kano21Research Division, NanoCarrier Co, Ltd, Chiba, Japan; 2Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; 3Department of Surgical Oncology, Osaka City University, Osaka, JapanAbstract: Drug release rate is an important factor in determining efficacy and toxicity of nanoscale drug delivery systems. However, optimization of the release rate in polymeric micellar nanoscale drug delivery systems has not been fully investigated. In this study NC-6301, a poly(ethylene glycol-poly(aspartate block copolymer with docetaxel (DTX covalently bound via ester link, was synthesized with various numbers of DTX molecules bound to the polymer backbone. The number of DTX molecules was determined up to 14 to achieve an optimal release rate, based upon the authors' own pharmacokinetic model using known patient data. Efficacy and toxicity of the formulation was then tested in animals. When administered three times at 4-day intervals, the maximum tolerated doses of NC-6301 and native DTX were 50 and 10 mg/kg, respectively, in nude mice. Tissue distribution studies of NC-6301 in mice at 50 mg/kg revealed prolonged release of free DTX in the tumor for at least 120 hours, thus supporting its effectiveness. Furthermore, in cynomolgus monkeys, NC-6301 at 6 mg/kg three times at 2-week intervals showed marginal toxicity, whereas native DTX, at 3 mg/kg with the same schedule, induced significant decrease of food consumption and neutrophil count. NC-6301 at 50 mg/kg in mice also regressed a xenografted tumor of MDA-MB-231 human breast cancer. Native DTX, on the other hand, produced only transient and slight regression of the same tumor xenograft. NC-6301 also significantly inhibited growth of OCUM-2MLN human scirrhous gastric carcinoma in an orthotopic mouse

  10. Sequential interactions of silver-silica nanocomposite (Ag-SiO2 NC) with cell wall, metabolism and genetic stability of Pseudomonas aeruginosa, a multiple antibiotic-resistant bacterium

    Digital Repository Service at National Institute of Oceanography (India)

    Anas, A.; Jiya, J.; Rameez, M.J.; Anand, P.B.; Anantharaman, M.R.; Nair, S.

    in the proportion of fatty acids after the treatment. Inside the cytoplasm, a complete inhibition of electron transport system was achieved with 100 mu g ml sup(-1) Ag-SiO sub(2)NC, followed by DNA breakage. The study thus demonstrates that Ag-SiO sub(2)NC invades...

  11. Highly conducting phosphorous doped Nc-Si:H thin films deposited at high deposition rate by hot-wire chemical vapor deposition method.

    Science.gov (United States)

    Waman, V S; Kamble, M M; Ghosh, S S; Mayabadi, Azam; Sathe, V G; Amalnekar, D P; Pathan, H M; Jadkar, S R

    2012-11-01

    In this paper, we report the synthesis of highly conducting phosphorous doped hydrogenated nanocrystalline silicon (nc-Si:H) films at substantially low substrate temperature (200 degrees C) by hot-wire chemical vapor deposition (HW-CVD) method using pure silane (SiH4) and phosphine (PH3) gas mixture without hydrogen dilution. Structural, optical and electrical properties of these films were investigated as a function of PH3 gas-phase ratio. The characterization of these films by low-angle X-ray diffraction, Raman spectroscopy and atomic force microscopy revealed that, the incorporation of phosphorous in nc-Si:H induces an amorphization in the nc-Si:H film structure. Fourier transform infrared spectroscopy analysis indicates that hydrogen predominately incorporated in phosphorous doped n-type nc-Si:H films mainly in di-hydrogen species (Si-H2) and poly-hydrogen (Si-H2)n bonded species signifying that the films become porous, and micro-void rich. We have observed high band gap (1.97-2.37 eV) in the films, though the hydrogen content is low (< 1.4 at.%) over the entire range of PH3 gas-phase ratio studied. Under the optimum deposition conditions, phosphorous doped nc-Si:H films with high dark conductivity (sigma Dark -5.3 S/cm), low charge-carrier activation energy (E(act) - 132 meV) and high band gap (- 2.01 eV), low hydrogen content (- 0.74 at.%) were obtained at high deposition rate (12.9 angstroms/s).

  12. Dependence of Microstructure and Hardness of Nanocomposite Coatings of nc-(Ti1-xAlxN)/a-Si3N4 on Aluminum Contents

    Institute of Scientific and Technical Information of China (English)

    MA Sheng-li; MA Da-yan; XU Ke-wei

    2004-01-01

    Super-hard nanocomposite coatings have been received a great attention during recent years. Based on our previous investigations onto the several super-hard nanocomposite coating systems including nc-TiN/a-Si3N4,nc-TiN/a-BN. This paper reports on the nc-(Ti1-xAlxN)/a-Si3N4 nanocomposite coatings prepared by direct current plasma enhanced chemical vapor deposition (PECVD). And the effect of aluminum contents on the microstructure and hardness of the coatings have been mainly investigated. The coatings were characterized by means of X-ray diffraction (XRD),X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) equipped with energy dispersive analysis of X-rays (EDX), and the hardness measurements were done by means of the automated load-depth sensing technique using Vickers diamond indenter. The thermal stability of nanocomposite coatings of TiN/a-Si3N4 was evaluated by annealing at elevated temperatures up to 1000℃. The results shows that super hardness of nc-(Ti1-xAlxN)/a-Si3N4 could be obtained with a wide aluminum content from 10at.% to 86at.% in (Ti1-xAlx)N phase, while the silicon content can be kept at 4~5 at.%. These nanocomposite coatings shows a relatively better thermal stability of nanocrystallite size and therefore high hardness up to 1000℃, which further support our earlier concept for the design of super-hard nanocomposite coatings. These results are suggested mainly due to the formation of nanostructure, and this indicates that the aluminum has also the role of controlling the crystallite size within nc-(Ti1-xAlxN)/a-Si3N4 besides its known well property of the super anti-oxidation.

  13. Dependence of Microstructure and Hardness of Nanocomposite Coatings of nc-(Ti1-xAlxN)/a-Si3N4 on Aluminum Contents

    Institute of Scientific and Technical Information of China (English)

    MASheng-li; MADa-yan; XUKe-wei

    2004-01-01

    Super-hard nanocomposite coatings have been received a great attention during recent years. Based on our previous investigations onto the several super-hard nanocomposite coating systems including nc-TiN/a-Si3N4,nc-TiN/a-BN. This paper reports on the nc-(Ti1-xAlxN)/a-Si3N4 nanocomposite coatings prepared by direct current plasma enhanced chemical vapor deposition (PECVD). And the effect of aluminum contents on the microstructure and hardness of the coatings have been mainly investigated. The coatings were characterized by means of X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) equipped with energy dispersive analysis of X-rays (EDX), and the hardness measurements were done by means of the automated load-depth sensing technique using Vickers diamond indenter. The thermal stability of nanocomposite coatings of TiN/a-Si3N4 was evaluated by annealing at elevated temperatures up to 1000~C. The results shows that super hardness of nc-(Til_xAlxN)/a-Si3N4 could be obtained with a wide aluminum content from 10at.% to 86at.% in (Til-xAlx)N phase, while the silicon content can be kept at 4-5 at.%. These nanocomposite coatings shows a relatively better thermal stability of nanocrystallite size and therefore high hardness up to 1000~C, which further support our earlier concept for the design of super-hard nanocomposite coatings. These results are suggested mainly due to the formation of nanostructure, and this indicates that the aluminum has also the role of controlling the crystallite size within nc-(Ti1-xAlxN)/a-Si3N4 besides its known well property of the super anti-oxidation.

  14. Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene.

    Directory of Open Access Journals (Sweden)

    Tewarit Sarachana

    Full Text Available Hemophilia A (HA is a bleeding disorder caused by deficiency of functional plasma clotting factor VIII (FVIII. Genetic mutations in the gene encoding FVIII (F8 have been extensively studied. Over a thousand different mutations have been reported in the F8 gene. These span a diverse range of mutation types, namely, missense, splice-site, deletions of single and multiple exons, inversions, etc. There is nonetheless evidence that other molecular mechanisms, in addition to mutations in the gene encoding the FVIII protein, may be involved in the pathobiology of HA. In this study, global small ncRNA expression profiling analysis of whole blood from HA patients, and controls, was performed using high-throughput ncRNA microarrays. Patients were further sub-divided into those that developed neutralizing-anti-FVIII antibodies (inhibitors and those that did not. Selected differentially expressed ncRNAs were validated by quantitative reverse transcription-polymerase chain reaction (qRT-PCR analysis. We identified several ncRNAs, and among them hsa-miR-1246 was significantly up-regulated in HA patients. In addition, miR-1246 showed a six-fold higher expression in HA patients without inhibitors. We have identified an miR-1246 target site in the noncoding region of F8 mRNA and were able to confirm the suppressory role of hsa-miR-1246 on F8 expression in a stable lymphoblastoid cell line expressing FVIII. These findings suggest several testable hypotheses vis-à-vis the role of nc-RNAs in the regulation of F8 expression. These hypotheses have not been exhaustively tested in this study as they require carefully curated clinical samples.

  15. Mechanical Properties of NC/NG/AP/Al Composite Modified Double-Base Propellant%NC/NG/AP/Al复合改性双基推进剂力学性能研究

    Institute of Scientific and Technical Information of China (English)

    李吉祯; 樊学忠; 钟雷; 刘小刚

    2007-01-01

    研究了硝化棉含量、固体组分粒度级配和固化剂对NC/NG/AP/Al复合改性双基(CMDB)推进剂的力学性能的影响.结果表明,随NC含量的降低,CMDB推进剂+20 ℃和+50 ℃下的抗拉强度降低,硝化棉的质量百分含量为20%时,推进剂的伸长率出现最大值;固体组分的粒度级配对CMDB推进剂的力学性能有较大的影响,AP(96.8 μm)、RDX(44.9 μm)和Al(10.8 μm)质量百分含量的比值为1:1:1时,该推进剂力学性能为最佳;硝化棉含量较少的CMDB推进剂体系,进行适度交联固化可在一定程度上提高抗拉强度,明显提高推进剂的伸长率.

  16. 75 FR 77675 - AREVA NP, Inc.; Confirmatory Order (Effective Immediately)

    Science.gov (United States)

    2010-12-13

    ... Exchange (EIE), users will be required to install a Web browser plug-in from the NRC Web site. Further information on the Web-based submission form, including the installation of the Web browser plug-in, is... be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The...

  17. ERVA - AREVAs Alternative Way for Spare Parts Management

    Energy Technology Data Exchange (ETDEWEB)

    Hoppe, H.

    2014-07-01

    The availability of equipment and systems in power plants throughout the life of the plant is a key challenge for plant operators. Therefore, the management of spare parts during the entire life cycle of a plant is of particular importance. In order to maintain the functionality of the equipment without retrofit or re-design it is important to have original parts available for use or to ensure there is adequate stock available for the future. (Author)

  18. Discuss of the Fault of Paranormal Dew Point Temperature for NC-1A/B General Air Compressor%NC-1A/B型通用空气压缩机车露点温度超差故障探讨

    Institute of Scientific and Technical Information of China (English)

    王为奎; 李涛

    2012-01-01

    The NC-1A/B general air compressor is a kind of high-pressure gas equipment and a macro-equipment largely used in army. It ofen comes forth the paranormal dew point tenperature issue. The causes of paranormal dew point tenperature issue are discussed and the concrete improvemnet measures are given in this paper.%NC-1A/B型通用空气压缩机车是部队大量使用的高压气体设备,是一种通用气源设备,在使用中经常出现露点温度超差问题.针对NC-1A/B型通用空气压缩机车露点温度超差问题的原因进行了初步探讨,并给出具体改进措施.

  19. Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice

    Directory of Open Access Journals (Sweden)

    Heerim Kang

    2015-09-01

    Full Text Available Atopic dermatitis (AD is a chronic and inflammatory skin disease that can place a significant burden on quality of life for patients. AD most frequently appears under the age of six and although its prevalence is increasing worldwide, therapeutic treatment options are limited. Chlorella vulgaris (CV is a species of the freshwater green algae genus chlorella, and has been reported to modulate allergy-inducible factors when ingested. Here, we examined the effect of CV supplementation on AD-like symptoms in NC/Nga mice. CV was orally administrated for six weeks while AD-like symptoms were induced via topical application of Dermatophagoides farinae extract (DFE. CV treatment reduced dermatitis scores, epidermal thickness, and skin hydration. Histological analysis also revealed that CV treatment reduced DFE-induced eosinophil and mast cell infiltration into the skin, while analysis of serum chemokine levels indicated that CV treatment downregulated thymus- and activation-regulated chemokine (TARC and macrophage-derived chemokine (MDC levels. In addition, CV treatment downregulated mRNA expression levels of IL-4 and IFN-γ. Taken together, these results suggest that CV extract may have potential as a nutraceutical ingredient for the prevention of AD.

  20. Uncertainty analysis of a spatially-explicit annual water-balance model: case study of the Cape Fear catchment, NC

    Directory of Open Access Journals (Sweden)

    P. Hamel

    2014-10-01

    Full Text Available There is an increasing demand for assessment of water provisioning ecosystem services. While simple models with low data and expertise requirements are attractive, their use as decision-aid tools should be supported by uncertainty characterization. We assessed the performance of the InVEST annual water yield model, a popular tool for ecosystem service assessment based on the Budyko framework. Our study involved the comparison of ten subcatchments in the Cape Fear watershed, NC, ranging in size and land use configuration. We analyzed the model sensitivity to the eco-hydrological parameters and the effect of extrapolating a lumped theory to a fully distributed model. Comparison of the model predictions with observations and with a lumped water balance model confirmed that the model is able to represent differences in land uses. Our results also emphasize the effect of climate input errors, especially annual precipitation, and errors in the eco-hydrological parameter Z, which are both comparable to the model structure uncertainties. In practice, our case study supports the use of the model for predicting land use change effect on water provisioning, although its use for identifying areas of high water yield will be influenced by precipitation errors. While the results are inherently local, analysis of the model structure suggests that many insights from this study will hold globally. Further work toward characterization of uncertainties in such simple models will help identify the regions and decision contexts where the model predictions may be used with confidence.

  1. An NC-AFM and KPFM study of the adsorption of a triphenylene derivative on KBr(001

    Directory of Open Access Journals (Sweden)

    Antoine Hinaut

    2012-03-01

    Full Text Available The adsorption on KBr(001 of a specially designed molecule, consisting of a flat aromatic triphenylene core equipped with six flexible propyl chains ending with polar cyano groups, is investigated by using atomic force microscopy in the noncontact mode (NC-AFM coupled to Kelvin probe force microscopy (KPFM in ultrahigh vacuum at room temperature. Two types of monolayers are identified, one in which the molecules lie flat on the surface (MLh and another in which they stand approximately upright (MLv. The Kelvin voltage on these two structures is negatively shifted relative to that of the clean KBr surface, revealing the presence of surface dipoles with a component pointing along the normal to the surface. These findings are interpreted with the help of numerical simulations. It is shown that the surface–molecule interaction is dominated by the electrostatic interaction of the cyano groups with the K+ ions of the substrate. The molecule is strongly adsorbed in the MLh structure with an adsorption energy of 1.8 eV. In the MLv layer, the molecules form π-stacked rows aligned along the polar directions of the KBr surface. In these rows, the molecules are less strongly bound to the substrate, but the structure is stabilized by the strong intermolecular interaction due to π-stacking.

  2. Simple estimation of electron correlation energy for multi-atomic strong ionic compounds KX and (KX)2 (X = OH, NC)

    Institute of Scientific and Technical Information of China (English)

    禚淑苹; 韦吉崇; 陈德展; 居冠之

    2002-01-01

    On the basis of the calculations and analyses of the intrapair and interpair correlation energy of KX (X = OH, NC) molecules and the results of the transferability of both the innermost intrapair correlation energy and the inner core effect of K and X in KX molecules, we defined and calculated the Kδ+ and Xδ-correlation contributions to the total correlation energy of KX molecules. With the comparison of the pair correlation energy of K+, X-and KX systems, we present a simple estimation method to estimate the electron correlation energy of strong ionic compound by summarizing the correlation energy of its constituent ion and ionic group. By using this simple method, the reasonable estimation results of the correlation energy of (KOH)2 and (KNC)2 have been obtained at mp2/6-311++G(d) level with Gaussian98 program, and the deviations are very small. Applying the scheme of "Separate Large System into Smaller Ones" to the calculation of electron correlation energy of large ionic compounds, it can not only save lot of computation work but also reach the chemical accuracy.

  3. Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice.

    Science.gov (United States)

    Kang, Heerim; Lee, Chang Hyung; Kim, Jong Rhan; Kwon, Jung Yeon; Seo, Sang Gwon; Han, Jae Gab; Kim, Byung Gon; Kim, Jong-Eun; Lee, Ki Won

    2015-09-02

    Atopic dermatitis (AD) is a chronic and inflammatory skin disease that can place a significant burden on quality of life for patients. AD most frequently appears under the age of six and although its prevalence is increasing worldwide, therapeutic treatment options are limited. Chlorella vulgaris (CV) is a species of the freshwater green algae genus chlorella, and has been reported to modulate allergy-inducible factors when ingested. Here, we examined the effect of CV supplementation on AD-like symptoms in NC/Nga mice. CV was orally administrated for six weeks while AD-like symptoms were induced via topical application of Dermatophagoides farinae extract (DFE). CV treatment reduced dermatitis scores, epidermal thickness, and skin hydration. Histological analysis also revealed that CV treatment reduced DFE-induced eosinophil and mast cell infiltration into the skin, while analysis of serum chemokine levels indicated that CV treatment downregulated thymus- and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) levels. In addition, CV treatment downregulated mRNA expression levels of IL-4 and IFN-γ. Taken together, these results suggest that CV extract may have potential as a nutraceutical ingredient for the prevention of AD.

  4. Therapeutic Effects of Fermented Flax Seed Oil on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

    Science.gov (United States)

    Yang, Joonhyoung; Min, Sangyeon

    2017-01-01

    Background. Atopic Dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Objective. This experiment aimed to study the effects of Fermented Flax Seed Oil (FFSO) on symptoms such as redness, eczema, and pruritus induced by AD. Materials and Methods. AD-induced NC/Nga mice were used to observe the immunological and therapeutic effects of FFSO on skin in vivo. Raw 264.7 cells were used to investigate the effects of FFSO in cells. Fc receptor expression and concentration of beta-hexosaminidase were measured. Nitric oxide assay, Western blotting, real-time PCR, image analysis, and statistical analysis were performed in vitro. Results. In the immunohistochemical results, p-ERK 1/2 expression decreased, fibrogenesis strongly increased, and distribution reduction is observed. Distribution of IL-4-positive cells in the corium near the basal portion of the epithelium in the AT group was reduced. FFSO treatment reduced the number of cells showing NF-κB p65 and iNOS expression. The level of LXR in the AT group was higher than that in the AE group, and elevation of PKC expression was significantly reduced by FFSO treatment. Conclusion. FFSO could alleviate symptoms of AD such as epithelial damage, redness, swelling, and pruritus.

  5. C-fos protein expression in the anterior amygdaloid area and nc. accumbens in the hypoxic rat brain

    Directory of Open Access Journals (Sweden)

    Babović Siniša S.

    2014-01-01

    Full Text Available Introduction. By examining the production of c-Fos protein, we analyzed the response to the ischemic attack in different brain tissue, two of which are regions of the limbic system: the anterior amygdaloid area and nc. accumbens. Material and Methods. We used the model of rat brain ischemia - four-vessel occlusion, and Pulsinelli’s method. The rats were treated in two ways, according to which they were divided into two groups: a total ischemia (ligation of four blood vessels, i.e. electrocauterization of the vertebral artery with bilateral ligation of the carotid artery - the so-called R-group rats, and transient ischemic attack (ligation of four blood vessels, i.e. electrocauterization of the vertebral artery, with mutual re-ligation of the carotid arteries in the form of transient ischemia - the so-called T-group rats, which can also be called “pre-conditioned group”. Both groups had their own control group. Conclusion. We have concluded that parts of the brain with an important role for the survival have a strong expression of c-fos gene.

  6. A Novel Protein Elicitor (PeBA1) from Bacillus amyloliquefaciens NC6 Induces Systemic Resistance in Tobacco.

    Science.gov (United States)

    Wang, Ningbo; Liu, Mengjie; Guo, Lihua; Yang, Xiufen; Qiu, Dewen

    2016-01-01

    Here we reported a novel protein elicitor from Bacillus amyloliquefaciens NC6 induced systemic resistance (ISR) in tobacco. The purification was executed by ion-exchange chromatography, native-page extraction and HPLC, and the amino acid sequence was identified by mass spectrometry. This recombinant elicitor protein, expressed in Escherichia coli by an E1 expression vector, had good thermal stability, and the elicitor caused a clearly defined hypersensitive response (HR) necrosis in tobacco leaves. It could also trigger early defence events, including generation of reactive oxygen species (H2O2 and O2 (-)) and phenolic-compound accumulation. Quantitative real-time PCR (Q-RT-PCR) results indicated that several plant defence genes, including the salicylic acid (SA)-responsive PR1a, PR1b, PR5, and phenylalanine ammonia lyase (PAL), as well as the jasmonic acid (JA)-responsive PDF1.2 and CORONATINE INSENSITIVE 1 (COI1), were all up-regulated. Moreover, infiltration conferred systemic resistance against a broad spectrum of pathogens, including Tobacco mosaic virus (TMV) and the fungal pathogen Botrytis cinerea.

  7. Foetal death in naive heifers inoculated with Neospora caninum isolate Nc-Spain7 at 110 days of pregnancy.

    Science.gov (United States)

    Almería, Sonia; Serrano-Perez, Beatriz; Darwich, Laila; Domingo, Mariano; Mur-Novales, Ramon; Regidor-Cerrillo, Javier; Cabezón, Oscar; Pérez-Maillo, Mónica; Lopez-Helguera, Irene; Fernández-Aguilar, Xavier; Puig-Ribas, Maria; Ortega-Mora, Luis Miguel; García-Ispierto, Irina; Dubey, Jitender P; López-Gatius, Fernando

    2016-09-01

    Neospora caninum infection is a leading cause of abortion in cattle worldwide. The pathogenesis of bovine neosporosis, particularly during the second term of gestation when most abortions occur in naturally infected dams, is poorly understood. In the present study foetal death was observed in 3 of 6 experimentally infected dams at 110 days of gestation after 6 weeks of experimental period. All experimental heifers were febrile between 3 and 5 days post infection (dpi). Inoculated dams seroconverted by 3-4 weeks post-infection with higher mean antibody titres in aborting dams compared to non-aborting heifers, although not significantly (p > 0.05). Neospora caninum DNA was detected in all infected foetuses and placentas, and three infected foetuses also had N. caninum antibodies. The parasite burden was higher in the brain of dead/aborted foetuses than in live foetuses. Interestingly, high IFN-γ production was detected in foetal fluids of a dead foetus found upon euthanasia of its dam, while no IFN-γ was observed in amniotic, allantoic and/or foetal fluids in the three infected foetuses that were alive upon maternal euthanasia. The present study confirms that the infection of dams on gestation day 110 with 10(7) tachyzoites of the Nc-Spain7 isolate causes abortion. The fact that some infected dams aborted and some did not is relevant to the understanding of N. caninum pathogenesis of abortion in naturally infected cows.

  8. Influence of surface heterogeneities on reversibility of fullerene (nC60) nanoparticle attachment in saturated porous media.

    Science.gov (United States)

    Shen, Chongyang; Zhang, Mengjia; Zhang, Shuzhen; Wang, Zhan; Zhang, Hongyan; Li, Baoguo; Huang, Yuanfang

    2015-06-15

    This study systematically investigated influence of surface roughness and surface chemical heterogeneity on attachment and detachment of nC60 nanoparticles in saturated porous media by conducting laboratory column experiments. Sand and glass beads were employed as a model collectors to represent a different surface roughness. The two collectors were treated by washing with only deionized water or by using acids to extensively remove chemical heterogeneities. Results show that both attachment and detachment were more in the acid-treated sand than those in the acid-treated glass beads. The greater attachment and detachment were attributed to the reason that sand surfaces have much more nanoscale asperities, which facilitates particle attachment atop of them at primary minima and subsequent detachment upon reduction of ionic strength. No detachment was observed if the water-washed collectors were employed, demonstrating that the couple of chemical heterogeneity with nanoscale roughness causes irreversible attachment in primary minima. Whereas existing studies frequently represented surface rough asperities as regular geometries (e.g., hemisphere, cone, pillar) for estimating influence of surface roughness on Derjaguin-Landau-Verwey-Overbeek (DLVO) interaction energies, our theoretical calculations indicate that the assumptions could underestimate both attachment and detachment because these geometries cannot account for surface curvature effects.

  9. Treatment system for contaminated water in Fukushima of Areva; Sistema de tratamiento de agua contaminada en Fukushima de Areva

    Energy Technology Data Exchange (ETDEWEB)

    Guillet, P.

    2012-07-01

    The Great East Japan earthquake and following tsunami that occurred on March 11, 2011 resulted in a very difficult situation on the site of the Fukushima Dai-Ichi NPP, TEPCO was facing a very difficult challenge to cool down the reactors. Following the implementation of an open circuit reactor cooling using seawater mixed seawater and freshwater began to accumulate in the basements of the reactors and turbine building on site. This eater was highly contaminated at different levels, due to contact with damaged fuel elements and contaminated elements. Despite efforts to increase water storage capacity, it was estimated that in end of June 2011, water would ever flow as storage capacity would be reached. The site was urgently in needed of a water decontamination system that would greatly reduce the activity of the water. This would allow a recirculation to cool the reactors, reduce the water storage needs and facilitate access for other site remediation operations by decreasing the activity on site. Quality of water to be processed was estimated at about 100,000 tons with contamination level reaching 1Ci/L. (Author)

  10. 抗BP180NC16A IgG亚型检测方法的建立以及在大疱性类天疱疮中的意义%Development of a method to detect anti-BP180NC16A IgG subclasses and the significance of antiBP180NC16A IgG in bullous pemphigoid

    Institute of Scientific and Technical Information of China (English)

    左亚刚; LIU Zhi

    2012-01-01

    目的 建立抗BP180NC16A IgG亚型的检测方法,并探讨其在大疱性类天疱疮(BP)中的意义.方法 原核表达GST-NC16A融合蛋白,并采用亲和层析法纯化.优化ELISA关键环节,建立抗BP180NC16A IgG各亚型的ELISA检测方法,并对10例未经治疗的BP、5例妊娠疱疹、1例成人线状IgA大疱性皮病、2例天疱疮患者血清分别进行检测.结果 通过方阵测定法确定GST-NC16A融合蛋白的包被浓度为500 μg/L,包被条件为4℃12h,血清稀释倍数为1∶100,酶标二抗为1∶2000,孵育条件为37℃1h,底物反应条件37℃20 min.10例大疱性类天疱疮患者10例IgG1阳性,9例IgG2阳性,5例IgG3阳性,9例IgG4阳性.2例寻常型天疱疮、1例成人线状IgA大疱性皮病均阴性.5例妊娠疱疹所有亚型均阳性,以IgG1和IgG3亚型为主.结论 抗BPI80NCI6A ELISA检测法特异性强、重复性好,是检测BP和妊娠疱疹患者抗BP180NC 16A抗体亚型的半定量方法.%Objective To develop an assay to quantitatively detect anti-BP180NC16A IgG subclasses and to assess the significance of anti-BP180NC16A lgG in bullous pemphigoid (BP).Methods The Glutathione S-transferase (GST)-BPI80NC16A fusion protein was expressed in E.coli system and purified by affinity chromatography.An improved enzyme-linked immunoabsorbent assay (ELISA) was developed and used to detect anti-BP180NCI6A IgG subclasses in serum samples from 10 patients with BP,5 patients with pemphigoid gestationis (PG),1 patient with linear IgA bullous dermatosis (LIBD) and 2 patients with pemphigus.Results The optimal condition for the ELISA was determined by cross assay as follows:the concentration of GSTBP180NC16A fusion protein for coating,500 μg/L; the condition for coating,4 ℃ for 12 hours; the dilution ratio of sera and secondary antibody,1∶ 100 and 1 ∶ 2000 respectively; the condition for incubation,37 ℃ for 1 hour;,the condition for the enzyme-substrate reaction,37 ℃ for 20 minutes.Of the 10 patients with BP

  11. Transform Ability and Individual Characteristics of an Atrazine-degrading Consortium NC1%阿特拉津降解群落NC1的降解特性和个体特性研究

    Institute of Scientific and Technical Information of China (English)

    叶金宇; 李艳华; 张金波; 高继国; 李海涛; 梁栋; 刘荣梅

    2015-01-01

    为筛选阿特拉津高效降解菌落和菌种资源,本研究利用富集培养法,从黑龙江省伊春市南岔区长期施用阿特拉津(2-氯-4-乙胺基-6-异丙胺基-1,3,5-三嗪,Atrazine)的玉米(Zea mays L.)地中筛选出阿特拉津降解群落NC1,此群落可以在36h内将100 mg/L阿特拉津降解为无毒的氰尿酸.通过无机盐平板直接分离法,分离出4株形态、颜色各不相同的菌株.通过生理生化和16S rDNA鉴定,菌株YJY1、YJY2、YJY3、和YJY5分别鉴定为肠道杆菌(Enterobacter sp.)、无色杆菌(Achromobacter xylosoxidans)、铜绿假单胞菌(Pseudomonas aeruginosa)和克雷白氏肺炎菌(Klebsiella pneumoniae).其中菌株YJY5可以以阿特拉津为唯一氮源生长.降解研究表明,该群落具有良好的阿特拉津降解效果,而且群落各成员间协同作用更接近于自然界阿特拉津的降解方式.本研究结果对阿特拉津污染的生物修复工作提供参考和借鉴意义.

  12. The Theory and Designing of Hand Economic Lathe NC Tool Carriage%手动经济型数控刀架的原理与设计

    Institute of Scientific and Technical Information of China (English)

    谭伟; 张济生; 张根保

    2000-01-01

    This text is subjected on “Hand Economic Lathe NC Tool Carriage”. Guided by this new idea. Through using the layout of tool carriage similar to Copying manufacture. Adding to a set new NC interpolation manner presented and completed specially and single coordinate control to the guilder this tool carriage the co-movement of tool carriage crisscross two coordinates is achieved.%手动经济型数控刀架采用类似于仿行刀架的布局形式,提出了一种新的数控插补方法,通过对单坐标的控制实现了两坐标联动的功能。

  13. The Theory and Designing of Hand Economic Lathe NC Tool Carriage%手动经济型数控刀架的原理与设计

    Institute of Scientific and Technical Information of China (English)

    谭伟; 张济生; 张根保

    2001-01-01

    This text is subjected on “Hand Economic Lathe NC Tool Carriage”.Guided by this new idea. Through using the layout of tool carriage similar to Copying manufacture. Adding to a set new NC interpolation manner presented and completed specially and single coordinate control to the guilder this tool carriage the co-movement of tool carriage crisscross two coordinates is achieved.%手动经济型数控刀架采用类似于仿行刀架的布局形式,提出了一种新的数控插补方法,通过对单坐标的控制实现了两坐标联动的功能。

  14. Structure аnd Physical-Mechanical Properties of nc-TiN Coatings Obtained by Vacuum-Arc Deposition and Deposition of HF Discharge

    Directory of Open Access Journals (Sweden)

    A.P. Sypylenko

    2011-01-01

    Full Text Available Using scanning electron microscopy (SEM, rengen-structural analysis (RSA, adhesion strength, friction coefficient and wear rate of the material and studied the properties of the coatings nc – TiN. Depending on the bias potential applied to the substrate and the chamber pressure, the inclusion of HF discharge, it is shown that the combination of different parameters recorded during scratching, allows us to distinguish the threshold of critical loads that are linked to different types of cohesive and adhesive fracture coatings in tribological tests. Sizes were determined nanograins nc – TiN stoichiometry of coatings, as well as the phase of elemental composition and morphology of the surface flooring.

  15. 回转体零件的数控加工工艺性分析%NC Machining Processing Analysis of Rotary Part

    Institute of Scientific and Technical Information of China (English)

    王娟平

    2011-01-01

    以典型的回转体类零件为例,介绍零件的数控加工工艺性分析方法.根据零件的结构特点选择机床,然后进行零件的图样分析、结构工艺性分析和安装方式的选择,为后续的数控加工工艺路线的设计研究做好准备.%The way of NC machining processing analysis was introduced by an example of rotary part. According to part featere, machine tool was chosen. Then part chawing analysis, analysis of structure process, selection rf fixed way were made. All of above provides hasis tat the design of NC machining process path.

  16. Nuclear magnetic resonance study of the ferroelastic phase transition of order-disorder type in [N(C2H5)4]2CdCl4

    Science.gov (United States)

    Lim, Ae Ran; Kim, Min Soo; Lim, Kye-Young

    2016-08-01

    This study uses nuclear magnetic resonance (NMR) techniques to examine the detailed changes in [N(C2H5)4]2CdCl4 around its phase transition at the temperature TC = 284 K. The chemical shifts and spin-lattice relaxation times in the rotating frame (T1ρ) were determined from 1H magic angle spinning (MAS) NMR and 13C cross-polarization (CP)/MAS NMR spectra. The two sets of inequivalent 1H and 13C nuclei in CH3 and CH2 were distinguished. A ferroelastic phase transition was observed at TC, without structural symmetry change. The phase transition is mainly attributed to the orientational ordering of the [N(C2H5)4]+ cations, and the spectral splitting at low temperature is associated with different ferroelastic domains.

  17. 基于XSLT的通用STEP-NC后置处理器开发%Development of universal STEP-NC post processor based on XSLT

    Institute of Scientific and Technical Information of China (English)

    肖文磊; 郇极

    2012-01-01

    To make STandard for the Exchange of Product model data-Numerical Control(STEP-NC)was compatible with traditional NC systems,the special STEP-NC post-processor was necessary for each traditional NC system.Thus,a general post-processor was created to reduce the development workloads and difficulties in constructing the special STEP-NC post-processor.By using STEP-NC code in eXtensible Markup Language(XML)mode as the post-processor input and the eXtensible Stylesheet Language Transformations(XSLT)based transformation mechanism,the post processing oriented to unification of different NC machining equipments was realized.According to transfer principle and requirement of XSLT,the data converters for EXPRESS-X and P21-P28 were individually developed.A general post-processor was constructed which took P28 file as data input and XSLT style sheet as machine equipment interface format.A cutting robot and a 3-Axis NC machining were taken as application examples,which accepted robot language and G-code respectively as the cutter location data.The results testified and verified the functionality and feasibility of the proposed post-processor.%为了使STEP-NC兼容传统的数控系统,需要在传统数控系统上构建专用的STEP-NC后置处理器。为此,建立了一个通用的后置处理器,以降低构建专用STEP后置处理器的开发工作量和开发难度。采用可扩展标记语言模式下的STEP-NC代码作为输入和基于可扩展样式表语言转换的转换机制,实现面向不同数控加工设备统一化的后置处理过程。根据可扩展样式表语言转换原理和要求,分别开发了EXPRESS-X和P21-P28的文件格式转换器。构建了以P28格式作为输入和以XSLT样式表语言定义机床设备接口格式的通用后置处理器。以一台切削加工机器人和一台三轴数控铣床为应用实例,分别以机器人语言和G代码作为后置处理结果,对后置处理器的功能性和可行性进行了验证。

  18. Glutamine Assimilation and Feedback Regulation of L-acetyl-N-glutamate Kinase Activity in Chlorella variabilis NC64A Results in Changes in Arginine Pools.

    Science.gov (United States)

    Minaeva, Ekaterina; Forchhammer, Karl; Ermilova, Elena

    2015-11-01

    Glutamine is a metabolite of central importance in nitrogen metabolism of microorganisms and plants. The Chlorella PII signaling protein controls, in a glutamine-dependent manner, the key enzyme of the ornithine/arginine biosynthesis pathway, N-acetyl-L-glutamate kinase (NAGK) that leads to arginine formation. We provide evidence that glutamine promotes effective growth of C. variabilis strain NC64A. The present study shows that externally supplied glutamine directly influences the internal pool of arginine in NC64A. Glutamine synthetase (GS) catalyzes the ATP-dependent conversion of glutamate and ammonium to glutamine. The results of this study demonstrate that glutamine acts as a negative effector of GS activity. These data emphasize the importance of glutamine-dependent coupling of metabolism and signaling as components of an efficient pathway allowing the maintenance of metabolic homeostasis and sustaining growth of Chlorella.

  19. 数据驱动的NC代码自动生成方法研究%Study in NC code generating automatically based on data driving

    Institute of Scientific and Technical Information of China (English)

    李克天; 何汉武; 王志坚; 郑德涛; 陈统坚

    2001-01-01

    提出了以数据驱动方式来代替常规的人机交互方式对制造模型进行处理,最终可自动生成NC代码。论述了数据驱动文件原理、表达规则、运行方式以及生成NC代码的过程。%It was presented that data driving method used in manufacturing model instead of the method of manually, and NC code could be generated automatically. Its principle, expressing rules, and NC code creating of the data driving file were discussed step by step.

  20. Structural and Spectroscopic Properties of Linear Carbon Chains NC2nN and HC2n+1N (n = 1~10)

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jing-Lai; WU Wen-Peng; WANG Lian-Bin; CAO Ze-Xing

    2005-01-01

    Using density functional theory, geometries and vibrational frequencies of linear chains NC2nN and HC2n+1N (n = 1~ 10) have been investigated.Time-dependent density functional theory (TD-DFT) has been used to calculate the vertical transition energies and oscillator strengths for the X 1∑+k → 11∑+u transition in NC2nN (n = 1 ~10) and X1∑+ → 11∑+ transition in HC2n+1N (n =1 ~7).On the basis of present calculations, the explicit expressions for the size dependence of the excitation energy and the first adiabatic ionization energy in both carbon chains have been suggested.

  1. Rates of volcanic deposition, facies changes and movements in a dynamic basin: the Nuussuaq Basin, West Greenland, around the C27n-C26r transition

    DEFF Research Database (Denmark)

    Pedersen, A. K.; Larsen, L. M.; Riisager, P.

    2002-01-01

    the C27n-C26r transition (estimated duration less than 10 ka and here assumed to be 5 ka) as a c. 170 m thick zone within a succession of thin picritic lava flows. Multimodel photogrammetry combined with chemical and lithological analysis of the volcanic rocks has allowed detailed 3D analysis...... a record of synvolcanic differential movement of extensional fault blocks. The following parameters are estimated for the volcanism within the Nuussuaq Basin during the C27n-C26r transition: Production rate c. 0.042 km3 a−1, productivity c. 1.2 × 10−3 km3 a−1 km−1 (rift), volcanic aggradation c. 33 m ka−1...

  2. Structures of Highly Twisted Amides Relevant to Amide N-C Cross-Coupling: Evidence for Ground-State Amide Destabilization.

    Science.gov (United States)

    Pace, Vittorio; Holzer, Wolfgang; Meng, Guangrong; Shi, Shicheng; Lalancette, Roger; Szostak, Roman; Szostak, Michal

    2016-10-04

    Herein, we show that acyclic amides that have recently enabled a series of elusive transition-metal-catalyzed N-C activation/cross-coupling reactions are highly twisted around the N-C(O) axis by a new destabilization mechanism of the amide bond. A unique effect of the N-glutarimide substituent, leading to uniformly high twist (ca. 90°) irrespective of the steric effect at the carbon side of the amide bond has been found. This represents the first example of a twisted amide that does not bear significant steric hindrance at the α-carbon atom. The (15) N NMR data show linear correlations between electron density at nitrogen and amide bond twist. This study strongly supports the concept of amide bond ground-state twist as a blueprint for activation of amides toward N-C bond cleavage. The new mechanism offers considerable opportunities for organic synthesis and biological processes involving non-planar amide bonds.

  3. Temperature dependence of the spin Hall angle and switching current in the nc-W(O)/CoFeB/MgO system with perpendicular magnetic anisotropy

    Science.gov (United States)

    Neumann, L.; Meier, D.; Schmalhorst, J.; Rott, K.; Reiss, G.; Meinert, M.

    2016-10-01

    We investigated the temperature dependence of the switching current for a perpendicularly magnetized CoFeB film deposited on a nanocrystalline tungsten film with large oxygen content: nc-W(O). The effective spin Hall angle | ΘSH eff | ≈ 0.22 is independent of temperature, whereas the switching current increases strongly at low temperature. The increase indicates that the current induced switching itself is thermally activated, in agreement with a recent theoretical prediction. The dependence of the switching current on the in-plane assist field suggests the presence of an interfacial Dzyaloshinskii-Moriya interaction with D ≈ 0.23 mJ/m2, intermediate between the Pt/CoFe and Ta/CoFe systems. We show that the nc-W(O) is insensitive to annealing, which makes this system a good choice for the integration into magnetic memory or logic devices that require a high-temperature annealing process during fabrication.

  4. Fluorescence Quenching of Anthracene by N,N-Diethylaniline and Phenothiazine in Triton X-100/n-C10H21OH/H2O Microemulsion

    Institute of Scientific and Technical Information of China (English)

    GUO Xia; XU Hui; GUO Rong

    2003-01-01

    The photo-induced electron transfer reactions of anthracene with N,N-diethylaniline(DEA) and phenothiazine(PTZ) occur in the membrane phase of a Triton X-100/n-C10H21OH(1-decanol)/H2O microemulsion. DEA and PTZ exist in the membrane phase of the microemulsion. Anthracene exists in the oil continuous phase of the W/O microemulsion and in the oil core and membrane phase of the O/W microemulsion.

  5. TK42200 NC Boring and Milling Machine to Increase Transformation Tool%TK42200数控镗铣床增加刀库的改造

    Institute of Scientific and Technical Information of China (English)

    范芳洪

    2014-01-01

    In order to solve the TK42200 NC boring and milling machine to realize the automatic tool change, will increase in Machine Tool Retrofit techniques applied to the NC machine tool function expan-sion. Analysis of the method to control the tool change, proposed by NC and PLC combined control method of tool change, design the fixed cycle and the PLC control program NC changer. After debugging tool li-brary transformation can reliably tool change, tool change and product processing of experiment, the experi-mental results show that:the tool changing high repeat precision, the product quality, reducing the labor in-tensity of operators, by modifying the system variables to repair tool table the knife has the advantages of simple operation.%为了解决TK42200数控镗铣床实现自动换刀的问题,将在机床上增加刀库的改造技术应用到数控机床功能扩展中。开展了换刀控制方法的分析,提出了NC和PLC相结合共同控制换刀的方法,设计了NC换刀固定循环程序和PLC控制程序。刀库改造调试后能够稳定可靠地换刀,进行换刀和产品加工的实验,实验结果表明:换刀重复精度高,产品质量合格,减轻了操作人员劳动强度,通过修改系统变量来修复刀具表使刀库操作简单了。

  6. Selection of NC Milling Cutters for Prismatic Parts%非回转体零件数控铣刀的选择

    Institute of Scientific and Technical Information of China (English)

    王书建; 冯显英

    2012-01-01

    数控加工中刀具的选择除需遵循传统加工的选择规则外,还应遵循一些特殊的原则.基于MasterCAM和Vericut软件,从数控用铣刀的分类、刀具材料、工艺参数等几个方面研究数控加工中刀具选择的问题,给出刀具选择一般规则.同时考虑到软件中提供的刀具不符合车间实际的情况,提出建立刀具库的策略,可提高数控加工的编程效率,对数控技术的运用起到积极的促进作用.%Some special principles of selecting tools in NC manufacturing process should be followed in addition to that of the traditional manufacturing. The question of tool selection in NC process was researched from the tool classification, tool material and technics parameters based on MasterCAM and Vericut software. The general principles about tool selection were presented. At the same time concerning about the differences between tools provided by the software and the practical producing, the method of creating a tool library was put forward. The programming efficiency of NC machining can be enhanced, and the application of the NC technique can be promoted actively.

  7. Isolation and characterization of symbiotic mutants of bradyrhizobium sp. (Arachis) strain NC92: mutants with host-specific defects in nodulation and nitrogen fixation.

    OpenAIRE

    Wilson, K. J.; Anjaiah, V; Nambiar, P T; Ausubel, F M

    1987-01-01

    Random transposon Tn5 mutagenesis of Bradyrhizobium sp. (Arachis) strain NC92, a member of the cowpea cross-inoculation group, was carried out, and kanamycin-resistant transconjugants were tested for their symbiotic phenotype on three host plants: groundnut, siratro, and pigeonpea. Two nodulation (Nod- phenotype) mutants were isolated. One is unable to nodulate all three hosts and appears to contain an insertion in one of the common nodulation genes (nodABCD); the other is a host-specific nod...

  8. 长虹NC-2机芯同一功能元件损坏后两种故障表现

    Institute of Scientific and Technical Information of China (English)

    刘安明

    2001-01-01

    @@ 长虹NC-2机芯彩电电源电路设计复杂,各种保护电路齐全,这虽然提高电源的可靠性,但也给检修带来了麻烦,遇到疑难故障时,使人无从下手检修.现把从前检修过的两个实例整理出来,供同行参考.

  9. Effects of Lavender, Lemon and Eucalyptus Essential Oil on Th2 related Factors of DNCB-induced Atopy dermatitis in NC/Nga Mice Model

    Directory of Open Access Journals (Sweden)

    Kim, Hyeon-Ah

    2010-03-01

    Full Text Available Purpose : To investigate the effects of the lavender, lemon and eucalyptus oil mixture on the atopy dermatitis skin lesions induced on NC/Nga Mice by dinitrochlorobenzene (DNCB. Material and Method : For this purpose, we fabricated the oil mixture blending three essential oils (lavender, lemon, eucalyptus : ELL with one carrier oil (jojoba and apply it on the atopic dermatitis skin lesions of NC/Nga Mice. Atopic dermatitis in NC/Nga Mice was induced by DNCB treatment on the dorsal skin of mice for 8 weeks. The mixture of ratio of each essential oil drop was 1 (eucalyptus : 2 (lemon : 2 (lavender and this mixture was blended with jojoba oil 50ml (0.025%. The ELL-ointment was supplied for 8 weeks. We evaluated the effects of ELL on cell viability of mouse lung fibroblast, clinical skin features and severity, the level of serum Immunoglobulin (Ig E & Ig G1, Interleukin (IL-4, IL-13 and Interferon (IFN-. Results : ELL showed safety on the cell viability of mouse lung fibroblast compared with control group. The cell viability was measured by SRB method. The effects of ELL on clinical skin features and severity in DNCB-induced dermatitis model of NC/Nga mice was significant compared with control group. EEL also showed significant effects on clinical symptom score compared with control group. Serum IgE & IgG1 level and development of atopy dermatitis skin lesions were evaluated. Serum IgE & IgG1 production was significantly down-regulated in EEL group compared with control group. ELL also down-regulated the levels of IL-4 and IL-13, and up-regulated the level of IFN- compared with control group significantly. Conclusion : ELL was effective on atopy dermatitis by modulating Th2 related factors.

  10. Comparative analysis of the noncollagenous NC1 domain of type IV collagen: identification of structural features important for assembly, function, and pathogenesis.

    OpenAIRE

    Netzer, K. O.; Suzuki, K; Itoh, Y.; Hudson, B.G.; Khalifah, R. G.

    1998-01-01

    Type IV collagen alpha1-alpha6 chains have important roles in the assembly of basement membranes and are implicated in the pathogenesis of Goodpasture syndrome, an autoimmune disorder, and Alport syndrome, a hereditary renal disease. We report comparative sequence analyses and structural predictions of the noncollagenous C-terminal globular NC1 domain (28 sequences). The inferred tree verified that type IV collagen sequences fall into two groups, alpha1-like and alpha2-like, and suggested tha...

  11. 面向离散制造的混杂数控自治系统设计%Design of autonomous system for hybrid NC of discrete manufacturing

    Institute of Scientific and Technical Information of China (English)

    钱峰; 王德伦; 杜广宇

    2014-01-01

    研究离散制造中混杂数控生产线的智能化控制问题。引入智能感知、智能决策与智能执行等智能制造技术,构建生产线数控设备的联网协同机制,实现类似流程制造中自动化生产及无人值守的自治控制。基于信息物理融合系统(cyber physical systems,CPS)设计混杂数控自治系统(autonomous system for hybrid NC,ASHNC),提出具体架构与分层模型。采用WPF技术开发原型系统,并且在多个知名企业所构建的数控生产线中得到应用。实际效果验证了系统的可行性。%The intelligent control for hybrid NC production line in discrete manufacturing is studied. IntelliSense,smart decision-making and implementation of intelligent technologies are introduced,a networked-collaborative mechanism for hybrid NC production line is built,and a kind of autonomous control of unmanned production is implemented.Based on cyber physical systems,an autonomous system for hybrid NC is designed,a specific structure and a hierarchical model are proposed.A prototype system is developed using WPF technology.By the application of this research in some well-known enterprises,feasibility of the system has been well verified through practical effects.

  12. The launching of the construction of the Jules Horowitz Reactor; Lancement de la construction du reacteur de recherche Jules Horowitz

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2007-03-15

    In March 2007 the French deputy minister of industry has officially launched the construction of the new research reactor called Jules Horowitz (RJH) on the Cea site of Cadarache. RJH, that is due to operate in 2014, will be used to study the aging process of irradiated materials in any type of reactors, the behaviour of new nuclear fuels irradiated in different configurations and scenarios, and to produce radionuclides for nuclear medicine and high-quality doped silicon for the electronics industry. The investment that reaches 500 million euros is dispatched between Cea (50%), EDF (20%), Areva (10%) and foreign contributors (20%). (A.C.)

  13. 基于PMAC的开放式数控系统研究与应用%Study and Application on Open NC System Based on PMAC

    Institute of Scientific and Technical Information of China (English)

    李淑萍; 张筱云

    2009-01-01

    Summarized the states of NC system, enumerated several open NC system medals, further analyzed a kind of open NC system based on PC and PMAC motion cntroller. Introduced the characteris-tic of PMAC. As a research of application, Discussed the hardware structure and software design of LSWEDM (Low Speed Wire Cutting Electrical Discharge Machining). Approach is supplied that can be referenced by other similar research.%阐述了数控系统的发展概况.针对开放式数控系统,列举了目前已经出现的几种模式,并对基于PC+PMAC的开放式数控系统模式进行了分析研究.介绍了PMAC运动控制器的性能.作为实例应用,对慢走丝线切割机床开放武数控系统的硬件结构和软件设计进行了分析,为同类应用研究提供了有效的途径.

  14. Synthesis and Crystal Structure of an Ionic Compound [Fe(CN)6(phCH2NC5H5)3]·(H2O)4

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A novel ionic compound [Fe(CN)6(phCH2NC5H5)3]·(H2O)4(Mr = 794.71) has been synthesized and its structure was characterized by IR, elemental analysis and X-ray diffraction. The compound crystallizes in monoclinic, space group P21/c with a = 10.837(2), b = 16.551(3), c = 23.402(5) (A), β = 97.531(4)°V = 4161.0(15)(A)3, Z = 4, Dc = 1.269 g/cm3, F(000) = 1668, μ = 0.414 mm-1, R = 0.0479 and wR = 0.1232. The building unit of the title compound consists of three (phCH2N+C5H5) ions, one [Fe(CN)6]3- anion and four water molecules. According to the structural analysis, [Fe(CN)6]3- are linked together by O-H…N and O-H…O hydrogen bonds, but [Fe(CN)6]3- and [(phCH2N+C5H5)3] ions are bound by electrostatic force to form an ionic compound.Keywords: N-benzyl-pyridine, ferricyanic anion, crystal structure, supramolecular, ionic compound.

  15. Hydrogen insertion in titanium carbide based thin films (nc-TiC{sub x}/a-C:H) - comparison with bulk TiC{sub x}

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Julien; Jaoul, Cédric, E-mail: jaoul@ensil.unilim.fr; Glandut, Nicolas; Lefort, Pierre

    2016-08-01

    Nanocomposites composed of titanium carbide nanosized grains embedded in an amorphous hydrogenated carbon matrix (nc-TiC{sub x}/a-C:H) are prepared by hybrid Magnetron Sputtering - PECVD process using a titanium metal target and gaseous C{sub 6}H{sub 6}. By controlling the benzene flow rate, thin films with different carbon content are obtained. The structures of nc-TiC{sub x}/a-C:H materials are analyzed by X-ray diffraction, X-ray photoelectron and Raman spectroscopic methods. The electrochemical hydrogen insertion, as studied by cyclic voltammetry, strongly depends on the carbon content in the thin films. The correlation between the hydrogen insertion ability and the structure of materials are discussed. Furthermore, we show that the hydrogen insertion in these thin films reaches values much more significant than in bulk substoichiometric titanium carbide obtained by reactive sintering. - Highlights: • nc-TiC{sub x}/a-C:H thin films are prepared hybrid Magnetron Sputtering - PECVD process. • Different carbon contents are obtained by changing the hydrocarbon flowrate. • Expanded lattice parameter of the TiC{sub x} phase and a-C:H phase are observed. • Electrochemical hydrogen insertion strongly depends on the carbon content. • The maximum insertion is 22 times more important than bulk TiC{sub x}.

  16. Palladium-catalyzed Suzuki-Miyaura coupling of amides by carbon-nitrogen cleavage: general strategy for amide N-C bond activation.

    Science.gov (United States)

    Meng, Guangrong; Szostak, Michal

    2016-06-15

    The first palladium-catalyzed Suzuki-Miyaura cross-coupling of amides with boronic acids for the synthesis of ketones by sterically-controlled N-C bond activation is reported. The transformation is characterized by operational simplicity using bench-stable, commercial reagents and catalysts, and a broad substrate scope, including substrates with electron-donating and withdrawing groups on both coupling partners, steric-hindrance, heterocycles, halides, esters and ketones. The scope and limitations are presented in the synthesis of >60 functionalized ketones. Mechanistic studies provide insight into the catalytic cycle of the cross-coupling, including the first experimental evidence for Pd insertion into the amide N-C bond. The synthetic utility is showcased by a gram-scale cross-coupling and cross-coupling at room temperature. Most importantly, this process provides a blueprint for the development of a plethora of metal catalyzed reactions of typically inert amide bonds via acyl-metal intermediates. A unified strategy for amide bond activation to enable metal insertion into N-C amide bond is outlined ().

  17. Pioneering better science through the 3Rs: an introduction to the national centre for the replacement, refinement, and reduction of animals in research (NC3Rs).

    Science.gov (United States)

    Burden, Natalie; Chapman, Kathryn; Sewell, Fiona; Robinson, Vicky

    2015-03-01

    The National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) is an independent scientific organization that is based in the United Kingdom, which was set up by the government to lead the discovery and application of new technologies and approaches that minimize the use of animals in research and improve animal welfare. The NC3Rs uses a range of strategies to improve and advance science through application of the 3Rs. These include funding basic research, open innovation (CRACK IT), and programs run by inhouse scientists. We present several case studies from the NC3Rs portfolio, featuring asthma research, the use of nonhuman primates in monoclonal antibody development, and CRACK IT. Finally, we anticipate the future, as we use our experience to move into new research fields and expand toward international collaboration. Here we highlight how equipping scientists with relevant and emerging 3Rs tools can help overcome the challenges and limitations of the use of animals in research to the benefit of the whole bioscience community.

  18. Manual Implementation Scheme for NC Class B Macro%一种数控B类宏指令手工实现方案

    Institute of Scientific and Technical Information of China (English)

    彭云春

    2011-01-01

    从编译原理角度出发,采取确定有穷自动机的词法分析、自顶向下的语法分析,产生数控伪指令,通过数据栈来进行语义分析,手工实现数控B类宏指令.该方案思路清晰,简化程序设计,方便代码重用.其为国内数控系统对B类宏指令的编译实现,提供了一种行之有效的解决方案.%From the compilation theory point of view, deterministic finite state automata was used in lexieal analysis, top-down grammatical analysis to generate NC pseudo-instruction. Semantic analysis was carried out through data stack, then NC-B class macro was manually generated. The scheme has clear ideas, simplified programming and increased reusability of code. For the domestic numerical control system, an effective solution in compilation of NC-B class macro is provided.

  19. Quantification of Dune Response over the Course of a 6-Day Nor'Easter, Outer Banks, NC

    Science.gov (United States)

    Brodie, K. L.; Spore, N.; Swann, C.

    2014-12-01

    The amount and type of foredune morphologic change during a storm event primarily scales with the level of inundation during that event. Specifically, external hydrodynamic forcing (total water level) can be compared with antecedent beach and foredune morphology to predict an impact regime that relates to the type of expected morphologic evolution of the system. For example, when total water levels are above the dune toe, but below the dune crest, the impact regime is classified as "collision" and the expected morphology response is slumping or scarping of the dune face. While the amount of dune retreat scales largely with the duration of wave attack to the dune face, characteristics of the dune other than its crest or toe elevation may also enhance or impede rates of morphologic change. The aftermath of Hurricane Sandy provided a unique opportunity to observe alongshore variations in dune response to a 6-day Nor'Easter (Hs >4 m in 6 m depth), as a variety of dunes were constructed (or not) by individual home owners in preparation for the winter storm season. Daily terrestrial lidar scans were conducted along 20 km of coastline in Duck, NC using Coastal Lidar And Radar Imaging System (CLARIS) during the first dune collision event following Sandy. Foredunes were grouped by their pre-storm form (e.g. vegetated, pushed, scarped, etc) using automated feature extraction tools based on surface curvature and slope, and daily rates of morphologic volume change were calculated. The highest dune retreat rates were focused along a 1.5 km region where cross-shore erosion of recently pushed, un-vegetated dunes reached 2 m/day. Variations in dune response were analyzed in relation to their pre-storm morphology, with care taken to normalize for alongshore variations in hydrodynamic forcing. Ongoing research is focused on identifying specific metrics that can be easily extracted from topographic DEMs to aid in dune retreat predictions.

  20. A Study on Multi-defect Constrained Bendability of Thin-walled Tube NC Bending Under Different Clearance

    Institute of Scientific and Technical Information of China (English)

    LI Heng; YANG He

    2011-01-01

    Thin-walled tube numerical control (NC) bending is a tri-nonlinear physical process with multi-defect and multi-die constraints. The clearance on each contact interface is the major factor to indicate the contact conditions. A three-dimensional-finite element (3D-FE) model is established to consider the realistic dynamic boundary conditions of multiple dies under ABAQUS/Explicit platform. Combined with experiment, numerical study on bending behavior and bendability under different clearance between tube and various dies is conducted in terms of wrinkling, wall thinning and cross section deformation. The results show that (1)with smaller clearance of tube-wiper die and tube-mandrel, the wrinkling can be restrained while the wall thinning It and cross-section deformation Id increase; while excessive small clearance blocks tube materials to flow past tangent point and causes piles up, the onset of wrinkling enhances It and Id. (2)Both It and Id decrease with smaller clearance of tube-pressure die; the wrinkling possibility rises with larger clearance on this interface if the mandrel's freedom along Y-axis is opened; smaller clearance of tube-bend die prevents wrinkling while increases It, and the clearance on this interface has little effect on Id. (3)A modified Yoshida buckling test (YBT) is used to address the wrinkling mechanisms under normal constraints in tube bending: the smaller clearance may restrain wrinkling efficiently; the smaller wall thickness, the less critical clearance needed; the critical clearance for tube bending 38 mm× 1 mm×57 mm (tube outer diameter×wall thickness×centerline bending radius) equals about 20% of initial wall thickness.

  1. Forming limits under multi-index constraints in NC bending of aluminum alloy thin-walled tubes with large diameters

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    With increasing diameters of aluminum alloy thin-walled tubes (AATTs), the tube forming limits, i.e. the minimum bending factors, and their predictions under multi-index constraints including wrinkling, thinning and flattening have been being a key problem to be urgently solved for improving tube forming potential in numerical control (NC) bending processes of AATTs with large diameters. Thus in this paper, a search algorithm of the forming limits is put forward based on a 3D elastic-plastic finite element (FE) model and a wrinkling energy prediction model for the bending processes under axial compression loading (ACL) or not. This algorithm enables to be considered the effects of process parameter combinations including die, friction parameters on the multi-indices. Based on this algorithm, the forming limits of the different size tubes are obtained, and the roles of the process parameter combinations in enabling the limit bending processes are also revealed. The followings are found: the first, within the appropriate ranges of friction and clearances between the different dies and the tubes enabling the bending processes with smaller bending factors, the ACL enables the tube limit bending processes after a decrease of the mandrel ball thickness and diameters; then, without considering the effects of the tube geometry sizes on the tube constitutive equations, the forming limits will be decided by the limit thinning values for the tubes with diameters smaller than 80 mm, while the wrinkling for the tubes with diameters no less than 80 mm. The forming limits obtained from this algorithm are smaller than the analytical results, and reduced by 57.39%; the last, the roles of the process parameter combinations in enabling the limit bending processes are verified by experimental results.

  2. Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework

    Directory of Open Access Journals (Sweden)

    Toh Hiroyuki

    2008-04-01

    Full Text Available Abstract Background Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs. Recent studies, mainly based on various approximations of the Sankoff algorithm, have resulted in considerable improvement in the accuracy of pairwise structural alignment. In contrast, for the cases with more than two sequences, the practical merit of structural alignment remains unclear as compared to traditional sequence-based methods, although the importance of multiple structural alignment is widely recognized. Results We took a different approach from a straightforward extension of the Sankoff algorithm to the multiple alignments from the viewpoints of accuracy and time complexity. As a new option of the MAFFT alignment program, we developed a multiple RNA alignment framework, X-INS-i, which builds a multiple alignment with an iterative method incorporating structural information through two components: (1 pairwise structural alignments by an external pairwise alignment method such as SCARNA or LaRA and (2 a new objective function, Four-way Consistency, derived from the base-pairing probability of every sub-aligned group at every multiple alignment stage. Conclusion The BRAliBASE benchmark showed that X-INS-i outperforms other methods currently available in the sum-of-pairs score (SPS criterion. As a basis for predicting common secondary structure, the accuracy of the present method is comparable to or rather higher than those of the current leading methods such as RNA Sampler. The X-INS-i framework can be used for building a multiple RNA alignment from any combination of algorithms for pairwise RNA alignment and base-pairing probability. The source code is available at the webpage found in the Availability and requirements section.

  3. Preliminary Study on Mass Flow Rate in Passive Cooling Experimental Simulation During Transient Using NC-Queen Apparatus

    Directory of Open Access Journals (Sweden)

    M. Juarsa

    2014-12-01

    Full Text Available The research related to thermal management has been significantly inreased, especially for NPP safety. The use of passive cooling systems both during the accident and operation become reliable in the advanced reactor safety systems. Therefore it should be enhanced through experimental studies to investigate heat transfer phenomenon of the heat decay in transient cooling condition.An investigation has been performed through experiment using an NC-Queen apparatusconstructed with rectangular loop. Piping were consisting of tubes of SS316L with diameter, length, and width of 3/4 inch, 2.7 m, and 0.5 m respectively. The height between heater and cooler was 1.4 m. The experiment used initial water temperature at 70oC, 80oC, and 90oC in heater area. Transient temperature was used as experimental data to calculate water mass flow rate. The results showed that the temperature in heater area and cooler area were decreasing of about 90.6% and 95.7% at initial temperatur of 80oC, and of about 71.1% and 59.4% at initial temperature of 70oC. Those results were at higher initial temperature of 90oC compared with the initial temperature of 90oC. The average of water mass flow rate increased 81.03% from initial temperatur of 70oC. It was shown that the averages of removed heat in every second from water due to heat loss and cooler,were 3.51 watts, 5.06 watts and 6.85 watts respectively. The initial condition of heat stored in the water was quite different, but to the cooler heat removal capacity and heat loss was almost the same.

  4. 7,8,4'-Trihydroxyisoflavone attenuates DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice.

    Directory of Open Access Journals (Sweden)

    Heejung Kim

    Full Text Available Atopic dermatitis (AD is characterized by chronic highly pruritic and relapsing inflammatory skin lesions. Despite its growing prevalence, therapeutic treatments remain limited. Natural immune modulators from herbal extracts or derivatives may be useful for treating AD symptoms. This study examined the effect of 7,8,4'-trihydroxyisoflavone (7,8,4'-THIF, a metabolite of soy isoflavone daidzin, on AD-like symptoms. Repeated epicutaneous application of 2,4-dinitrochlorobenzene (DNCB was performed on the ear and dorsal skin of NC/Nga mice to induce AD-like symptoms and skin lesions, and 7,8,4'-THIF (200 and 400 nmol or tacrolimus (100 µg was applied topically for 3 weeks to assess their anti-pruritic effects. We found that 7,8,4'-THIF alleviated DNCB-induced AD-like symptoms as quantified by skin lesion, dermatitis score, ear thickness, and scratching behavior. Histopathological analysis demonstrated that 7,8,4'-THIF decreased DNCB-induced eosinophil and mast cell infiltration into skin lesions. We also found that 7,8,4'-THIF significantly alleviated DNCB-induced loss of water through the epidermal layer. In addition to reducing the DNCB-induced increase in serum IgE, 7,8,4'-THIF also lowered skin lesion levels of the chemokine thymus and activation regulated chemokine; Th2 cytokines interleukin (IL-4, IL-5, and IL-13; and Th1 cytokines IL-12 and interferon-γ. These results suggest that 7,8,4'-THIF might be a potential therapeutic candidate for the treatment of atopic dermatitis.

  5. Preparation and Thermochemistrg of Crystalline Compound( n-C12 H25 NH3 ) 2 CdCl4 ( s)%晶体化合物( n-C12 H25 NH3 ) 2 CdCl4 ( s )的制备及热化学研究

    Institute of Scientific and Technical Information of China (English)

    王晓兰; 王建军; 范妮; 张静; 倪俊超; 陈经涛

    2015-01-01

    The crystal compounds synthesized by the hydrothermal synthesis of (n-C12H25NH3)2 CdCl4(s);compound were calculated based on the thermochemical principle ( n-C12 H25 NH3 ) 2 CdCl4 ( s) of the lattice energy of 889. 81 kJ·mol-1 . Using isothermal solution reaction calorimeter,the standard molar enthalpy of the compound was obtained:[n-C12H25NH3)2 CdCl4,S] = - (1 836. 23 + 7. 95) kJ David mol-1.%用水热合成法合成了晶体化合物 (n-C12H25NH3)2 CdCl4(s);根据热化学原理计算了化合物(n-C12H25 NH3)2 CdCl4(s)的晶格能为889. 81 kJ·mol-1. 利用等温溶解-反应热量计,得到了该化合物的标准的摩尔焓: [(n-C12H25NH3)2 CdCl4,s] = -(1836.23 ±7.95) kJ·mol-1.

  6. TERRAIN, Mecklenburg County, NC

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix M: Data Capture Standards, describes the digital topographic data that was used to create...

  7. BASEMAP, MECKLENBURG, NC, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — FEMA Framework Basemap datasets comprise six of the seven FGDC themes of geospatial data that are used by most GIS applications (Note: the seventh framework theme,...

  8. Hydraulics, MECKLENBURG COUNTY, NC

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  9. Hydrology, MECKLENBURG COUNTY, NC

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  10. Comparison of indirect ELISA based on recombinant protein NcSRS2 and IFAT for detection of Neospora caninum antibodies in sheep Comparação entre ELISA baseado no antígeno recombinante NcSRS2 e RIFI para detecção de anticorpos de Neospora caninum em ovinos

    Directory of Open Access Journals (Sweden)

    Renato Andreotti

    2009-06-01

    Full Text Available Neospora caninum, an Apicomplexan parasite that can causes abortion, is responsible for considerable economic and reproductive losses in livestock. The purpose of the present study was to determine whether recombinant NcSRS2 is a suitable indirect ELISA antigen for determining specific immune response to N. caninum in sheep. A total of 441 serum samples were subjected to IFAT and rNcSRS2 based-ELISA, with both tests performing similarly. The sensitivity and specificity of indirect ELISA were 98.6 and 98.3%, respectively. The kappa index shows 0.98 concordance between the two tests, which is considered excellent. Seroprevalences of 30.8 and 32.0% were detected by IFAT and indirect ELISA, respectively, showing these tests did not differ significantly on this measure (p > 0.05. Serological analysis showed that HisG tag was detected by Western Blotting recognizing rNcSRS2 protein. The potential value of rNcSRS2-based ELISA as a highly specific and sensitive tool for serological diagnosis is also supported by the strong agreement found between IFAT and ELISA. The results support the potential use of recombinant protein NcSRS2 as an antigen in indirect ELISA in sheep.Neospora caninum é um parasito Apicomplexa que pode causar abortos e é reconhecido como agente importante responsável por perdas econômicas e reprodutivas. Este estudo avaliou a proteína recombinante NcSRS2 como antígeno para ELISA indireto na determinação de resposta imune para N. caninum em ovinos. 441 amostras de soro foram analisadas por IFAT e ELISA indireto com rNcSRS2 e ambos os testes revelaram comportamento similar. A sensibilidade e especificidade de ELISA indireto foram 98,6 e 98,3%, respectivamente. O índice kappa mostrou uma concordância entre os dois testes com valor de 0,98, que é considerado excelente. Prevalências de 30,8 e 32,0% detectadas por IFAT e ELISA indireto, respectivamente, mostraram que os testes não diferiram significativamente nesse aspecto (P

  11. Opto-electronic properties of P-doped nc-Si-QD/a-SiC:H thin films as foundation layer for all-Si solar cells in superstrate configuration

    Science.gov (United States)

    Kar, Debjit; Das, Debajyoti

    2016-07-01

    With the advent of nc-Si solar cells having improved stability, the efficient growth of nc-Si i-layer of the top cell of an efficient all-Si solar cell in the superstrate configuration prefers nc-Si n-layer as its substrate. Accordingly, a wide band gap and high conducting nc-Si alloy material is a basic requirement at the n-layer. Present investigation deals with the development of phosphorous doped n-type nanocrystalline silicon quantum dots embedded in hydrogenated amorphous silicon carbide (nc-Si-QD/a-SiC:H) hetero-structure films, wherein the optical band gap can be widened by the presence of Si-C bonds in the amorphous matrix and the embedded high density tiny nc-Si-QDs could provide high electrical conductivity, particularly in P-doped condition. The nc-Si-QDs simultaneously facilitate further widening of the optical band gap by virtue of the associated quantum confinement effect. A complete investigation has been made on the electrical transport phenomena involving charge transfer by tunneling and thermionic emission prevailing in n-type nc-Si-QD/a-SiC:H thin films. Their correlation with different phases of the specific heterostructure has been carried out for detailed understanding of the material, in order to improve its device applicability. The n-type nc-Si-QD/a-SiC:H films exhibit a thermally activated electrical transport above room temperature and multi-phonon hopping (MPH) below room temperature, involving defects in the amorphous phase and the grain-boundary region. The n-type nc-Si-QD/a-SiC:H films grown at ˜300 °C, demonstrating wide optical gap ˜1.86-1.96 eV and corresponding high electrical conductivity ˜4.5 × 10-1-1.4 × 10-2 S cm-1, deserve to be an effective foundation layer for the top nc-Si sub-cell of all-Si solar cells in n-i-p structure with superstrate configuration.

  12. Effects of anti-inflammatory and Rehmanniae radix pharmacopuncture on atopic dermatitis in NC/Nga mice.

    Science.gov (United States)

    Kim, Min-Chul; Lee, Chang-Hyun; Yook, Tae-Han

    2013-04-01

    Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritic and erythematous skin lesions. The purpose of this study was to investigate the suppressive effects of anti-inflammatory and Rehmanniae radix pharmacopuncture on the development of AD-like skin lesions in NC/Nga mice. The AD was induced on the mice's back skin by using biostir AD. The experimental groups were divided into three groups, PPI (anti-inflammatory pharmacopuncture), PPII (Rehmanniae radix pharmacopuncture, hydrodistillation extraction) and PPIII (Rehmanniae radix pharmacopuncture, MeOH extraction). All mice were treated using a 1-mL syringe to inject 0.1 mL of pharmacopuncture at right and left acupoints (BL13) on alternate days. In the control group, normal saline was used instead of pharmacopuncture. The following factors were investigated: (1) optical observations made with a handscope and clinical skin scores were evaluated; (2) tissue (general/immune) mast cells and CCR3(+) eosinophils, as well as vascular endothelial growth factor, fibroblast growth factor, and epidermal growth factor immunoreactive changes were evaluated; (3) CD4(+) and CD8(+) cells in the spleen were immunohistochemically examined; and, (4) the serum immunoglobulin (Ig)E level and lymphokines [interleukin (IL)-2, IL-4] were measured. In the PPI and the PPIII groups, the clinical skin score, total number of mast cells, CCR3(+) eosinophils immunoreaction, and total serum IgE, IL-2, and IL-4 levels were lower than the control group. The PPI and the PPIII groups also showed strong immunohistochemical reactions for vascular endothelial growth factor and fibroblast growth factor. The PPI group particularly showed a very strong immunohistochemical reaction for epidermal growth factor. All groups showed strong immune activity for CD8(+). The PPIII group showed strong immunity for both CD4(+) and CD8(+). From the above results, Rehmanniae radix pharmacopuncture (MeOH extraction) and anti

  13. 4. European forum of radiation protection sciences. Proceedings; 4e Forum Europeen de radioprotectique. Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    This 4. European forum of radiation protection sciences was the occasion for nuclear professionals to share their experience and to present the tools and techniques implemented in dismantling operations in the respect of radiation protection rules. This document brings together the abstracts and the available presentations given at this forum: 1 - Dismantling organisation and management - regulations: dismantling environment (A. Gay, Areva NC); Dismantling at the CEA (Ph. Guiberteau, DEN-Saclay); Optimisation of future dismantlement at the design and operation stage of facilities (P. Poncet, Areva); Action of the labour Ministry for workers radiation protection (T. Lahaye, DGT); 2 - Dismantling experience feedbacks 1: Radiation protection and dismantlement at Marcoule (J. Chardin, Areva NC); INB 106 dismantling (N. Pauwels, UDIL); Dismantling wastes management and valorisation of ALS and Saturne accelerators at Saclay (C. Salmon, CEA-Saclay); Chooz power plant deconstruction (L. Bardou, EDF); 3-4 - Dismantling projects: Phenix power plant dismantling (C. Beretti, CEA-Marcoule); Radiological characterization impact on the DGB project (H.C. Turbatte, F. Lemperiere, DGB Eurodif); Contribution of scientific calculations to reactor dismantling studies (A. Van Lauwe, CEA-Saclay); Acceptance committee of radiological cleansing companies (S. Faure, DPSN); Externalizing of the radiation protection skilled person (J.P. Piferrer, ATSR); International network of radiation protection professionals (G. Abela, EDF); 5 - Dismantling experience feedback 2: gloveboxes dismounting at La Hague plant (R. Choquet, P. Mougnard, Areva NC); Nuclear submarines dismantling in Russia (C. Deregel, Topp-Decide); Radioactive waste management of CERN accelerators (Y. Algoet, CERN); Nuclear facilities decommissioning (M. Berton, CEA, B. Marc, DRIM Sogeris); Asbestos removal in radiological environment (R. Blanc, Areva NC); 6-7-8 - Tools and methods: Aspilaser, decontamination by laser ablation (F

  14. 数控系统中混合型网络化通信系统研究%The reaserch on hybird network communication system in NC system

    Institute of Scientific and Technical Information of China (English)

    王鹏; 王琨琦

    2011-01-01

    提出了一种由有线通信与无线通信相结合的并应用于数控系统的混合型网络通信系统.利用上位机与下位机结合的操作方式来实现组网,上下位机以基于TCP/IP协议的工业以太网平台连接;另外,数控系统通过虚拟串口技术与外围设备PDA组建蓝牙微微网,PDA可实现数控系统无报警信号的故障诊断功能.上下位机网络通信程序利用Winsock控件在C++Builder6环境中设计;在evb3.0环境中编写了PDA接收数据程序.通过上述方法下位机在正常运行时,CAD、CAM、刀具轨迹、NC代码等信息可以发送给上位机.当数控系统正常运行时,下位机可将加工信息发送给PDA.数控系统中混合型网络通信系统的应用扩大了数控系统的功能同时提高了加工效率.%Wire communication network combiningwireless communication ,a hybrid network communication system applied in NC system is proposed,in which the operation mode of the upper computer combining the lower computer is adopted to create wire communication network. The lower computer is connected with the upper computer by the network cables and Ethernet switchboard which is adopted as the platform based on TCP/IP protocol. Besides, NC system is connected with PDA by virtual serial port technology to create Piconet and diagnose the no-alarm fault in virtual of Bluetooth technology. The communication program for Upper computer and the lower computer is designed in virtual of Winsock technology in C++Builder6.while the PDA receiving data module program is compiled by evb3.0.ln the experiment based on the method above,many functions, including CAD,CAM,cutter location calculating, NC code generation and so on,are achieved in upper computer to increase functions in NC system while the lower computer normally running. When the lower computer is connected with PDA,process information is successfully transferred to PDA to increase maintainable efficiency while NC system is running. The

  15. Taxonomic revision of the Malagasy members of the Nesomyrmex angulatus species group using the automated morphological species delineation protocol NC-PART-clustering

    Directory of Open Access Journals (Sweden)

    Sándor Csősz

    2016-03-01

    Full Text Available Background. Applying quantitative morphological approaches in systematics research is a promising way to discover cryptic biological diversity. Information obtained through twenty-first century science poses new challenges to taxonomy by offering the possibility of increased objectivity in independent and automated hypothesis formation. In recent years a number of promising new algorithmic approaches have been developed to recognize morphological diversity among insects based on multivariate morphometric analyses. These algorithms objectively delimit components in the data by automatically assigning objects into clusters. Method. In this paper, hypotheses on the diversity of the Malagasy Nesomyrmex angulatus group are formulated via a highly automated protocol involving a fusion of two algorithms, (1 Nest Centroid clustering (NC clustering and (2 Partitioning Algorithm based on Recursive Thresholding (PART. Both algorithms assign samples into clusters, making the class assignment results of different algorithms readily inferable. The results were tested by confirmatory cross-validated Linear Discriminant Analysis (LOOCV-LDA. Results. Here we reveal the diversity of a unique and largely unexplored fragment of the Malagasy ant fauna using NC-PART-clustering on continuous morphological data, an approach that brings increased objectivity to taxonomy. We describe eight morphologically distinct species, including seven new species: Nesomyrmex angulatus (Mayr, 1862, N. bidentatus sp. n., N. clypeatus sp. n., N. devius sp. n., N. exiguus sp. n., N. fragilis sp. n., N. gracilis sp. n., and N. hirtellus sp. n.. An identification key for their worker castes using morphometric data is provided. Conclusions. Combining the dimensionality reduction feature of NC clustering with the assignment of samples into clusters by PART advances the automatization of morphometry-based alpha taxonomy.

  16. C60 and Sc3N@C80(TMB-PPO derivatives as constituents of singlet oxygen generating, thiol-ene polymer nanocomposites

    Directory of Open Access Journals (Sweden)

    Ashli R. Toles

    2016-07-01

    Full Text Available Numerous functionalization methods have been employed to increase the solubility, and therefore, the processability of fullerenes in composite structures, and of these radical addition reactions continue to be an important methodology. C60 and Sc3N@C80 derivatives were prepared via radical addition of the photodecomposition products from the commercial photoinitiator TMB-PPO, yielding C60(TMB-PPO5 and Sc3N@C80(TMB-PPO3 as preferred soluble derivatives obtained in high yields. Characterization of the mixture of isomers using standard techniques suggests an overall 1PPO:6TMB ratio of addends, reflecting the increased reactivity of the carbon radical. Although, a higher percentage of PPO is observed in the Sc3N@C80(TMB-PPO3 population, perhaps due to reverse electronic requirements of the substrate. Visually dispersed thiol-ene nanocomposites with low extractables were prepared using two monomer compositions (PETMP:TTT and TMPMP:TMPDE with increasing fullerene derivative loading to probe network structure-property relationships. Thermal stability of the derivatives and the resulting networks decreased with increased functionality and at high fullerene loadings, respectively. TMPMP:TMPDE composite networks show well-dispersed derivatives via TEM imaging, and increasing Tg’s with fullerene loading, as expected for the incorporation of a more rigid network component. PETMP:TTT composites show phase separation in TEM, which is supported by the observed Tg’s. Singlet oxygen generation of the derivatives decreases with increased functionality; however, this is compensated for by the tremendous increase in solubility in organic solvents and miscibility with monomers. Most importantly, singlet oxygen generation from the composites increased with fullerene derivative loading, with good photostability of the networks.

  17. Integration of seismic interpretation and petrophysical studies on Hawaz Formation in J-field NC-186 concession, Northwest Murzuq basin, Libya

    Science.gov (United States)

    Mohamed, A. K.; Selim, E. I.; Kashlaf, A.

    2016-12-01

    This study has been carried out by the integration of seismic interpretations and the well-logging analysis of ten wells distributed in J-field of concession NC-186, Murzuq basin, Libya. Twenty (3D) seismic lines and ten wells have been analyzed. The results of this study indicated that, the main reservoir in this concession is Hawaz Formation. Hawaz has been split into 8 units with a subdivision of Hawaz H4 into three subunits with the objective of better characterization of the three general fine upward intervals. The lower interval of H4 zone presents the better reservoir properties. The depth of reflector H4 ranges from 4100 ft in the northwestern part of the study area and increases to 4600 ft in the southeastern part of the study area. In this study, the outline of the Hawaz paleohighs which is NC-186 Field "J" is generally trending in the NW-SE direction. The well logging analysis particularly quick look interpretation indicates that Hawaz Formation in the studied wells is mainly oil-bearing with some water-bearing sand levels at the horizons from H4 to and H6 which are potentially the main reservoirs. The water bearing zones are beyond these horizons starting from the sub-horizon H6c and the oil water contact is probably at depth 4495 ft. The crossplot of porosity-saturation for H5 and H6b indicates firmly that these horizons are indeed at irreducible state and will produce mainly oil as indicated in J4-NC186 well, while the crossplot of H8 shows wide scattering of points which is the main characteristic for water producing horizon. The depth of Hawaz Formation H4 is more than 4160 ft in J4, J12 and J16 wells in the northwestern parts of this field and increases to 4400 in the central part of the concession at well J1.

  18. 火药吸收药中硝化棉含量快速检测方法%A Rapid Detection Method of the NC Contentin Gunpowder Intermediate

    Institute of Scientific and Technical Information of China (English)

    尹作柱; 邓国栋; 朱陈森; 汪庆华

    2014-01-01

    For rapid detection of the nitrocellulose (NC)content in gunpowder intermediate,the near-infrared spectrograms of intermediate mixture system were collected by an optical fiber probe.The quantitative calibration model of component NC was established by Partial Least Squares (PLS)method through analyzing the spectral characteristics of pure NC and gunpowder intermediate,selecting 5 960-6 340 cm-1 and 7 665-9 193 cm-1 as modeling spectral region.The results show that the determination coefficient (R2 )of the model is 0.988 1 and root-mean-square error of prediction (RMSEP)is 0.2238,the predicted average relative error of the prediction set samples is 1 .23% and the detection time is less than 20 seconds,which can meet the need for continuous and automatic production of gunpowder.%为了快速检测火药吸收药中硝化棉的含量,采用光纤探头采集吸收药混合液体系的近红外光谱图,通过分析纯NC和吸收药混合体系的光谱图特性,选择5965~6340 cm-1和7665~9193 cm-1为建模区域,用偏最小二乘法对NC组分建立了定量校正模型。结果表明,模型的决定系数R2为0.9881,预测根方差RMSEP 为0.2238,预测集样本的预测平均相对误差为1.23%,检测时间小于20s,能够满足火药连续自动化生产的需要。

  19. Taxonomic revision of the Malagasy members of the Nesomyrmex angulatus species group using the automated morphological species delineation protocol NC-PART-clustering

    Science.gov (United States)

    Fisher, Brian L.

    2016-01-01

    Background. Applying quantitative morphological approaches in systematics research is a promising way to discover cryptic biological diversity. Information obtained through twenty-first century science poses new challenges to taxonomy by offering the possibility of increased objectivity in independent and automated hypothesis formation. In recent years a number of promising new algorithmic approaches have been developed to recognize morphological diversity among insects based on multivariate morphometric analyses. These algorithms objectively delimit components in the data by automatically assigning objects into clusters. Method. In this paper, hypotheses on the diversity of the Malagasy Nesomyrmex angulatus group are formulated via a highly automated protocol involving a fusion of two algorithms, (1) Nest Centroid clustering (NC clustering) and (2) Partitioning Algorithm based on Recursive Thresholding (PART). Both algorithms assign samples into clusters, making the class assignment results of different algorithms readily inferable. The results were tested by confirmatory cross-validated Linear Discriminant Analysis (LOOCV-LDA). Results. Here we reveal the diversity of a unique and largely unexplored fragment of the Malagasy ant fauna using NC-PART-clustering on continuous morphological data, an approach that brings increased objectivity to taxonomy. We describe eight morphologically distinct species, including seven new species: Nesomyrmex angulatus (Mayr, 1862), N. bidentatus sp. n., N. clypeatus sp. n., N. devius sp. n., N. exiguus sp. n., N. fragilis sp. n., N. gracilis sp. n., and N. hirtellus sp. n.. An identification key for their worker castes using morphometric data is provided. Conclusions. Combining the dimensionality reduction feature of NC clustering with the assignment of samples into clusters by PART advances the automatization of morphometry-based alpha taxonomy. PMID:26989630

  20. A novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagen

    Science.gov (United States)

    Gale, Daniel P.; Oygar, D. Deren; Lin, Fujun; Oygar, P. Derin; Khan, Nadia; Connor, Thomas M.F.; Lapsley, Marta; Maxwell, Patrick H.; Neild, Guy H.

    2016-01-01

    Background Hereditary microscopic haematuria often segregates with mutations of COL4A3, COL4A4 or COL4A5 but in half of families a gene is not identified. We investigated a Cypriot family with autosomal dominant microscopic haematuria with renal failure and kidney cysts. Methods We used genome-wide linkage analysis, whole exome sequencing and cosegregation analyses. Results We identified a novel frameshift mutation, c.4611_4612insG:p.T1537fs, in exon 49 of COL4A1. This mutation predicts truncation of the protein with disruption of the C-terminal part of the NC1 domain. We confirmed its presence in 20 family members, 17 with confirmed haematuria, 5 of whom also had stage 4 or 5 chronic kidney disease. Eleven family members exhibited kidney cysts (55% of those with the mutation), but muscle cramps or cerebral aneurysms were not observed and serum creatine kinase was normal in all individuals tested. Conclusions Missense mutations of COL4A1 that encode the CB3 [IV] segment of the triple helical domain (exons 24 and 25) are associated with HANAC syndrome (hereditary angiopathy, nephropathy, aneurysms and cramps). Missense mutations of COL4A1 that disrupt the NC1 domain are associated with antenatal cerebral haemorrhage and porencephaly, but not kidney disease. Our findings extend the spectrum of COL4A1 mutations linked with renal disease and demonstrate that the highly conserved C-terminal part of the NC1 domain of the α1 chain of type IV collagen is important in the integrity of glomerular basement membrane in humans. PMID:27190376